{"pmid": "4345158", "title": "Insulin secretion during hemorrhagic shock in dogs.", "content": "Insulin secretion during hemorrhagic shock in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345158"}
{"pmid": "4345159", "title": "A new technique of counting ( 32 P) phospholipids in liquid scintillation counter without added scintillator.", "content": "A new technique of counting ( 32 P) phospholipids in liquid scintillation counter without added scintillator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345159"}
{"pmid": "4345160", "title": "The electron spin resonance spectra of radical intermediates in the oxidation of ascorbic acid and related substances.", "content": "The electron spin resonance spectra of radical intermediates in the oxidation of ascorbic acid and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345160"}
{"pmid": "4345161", "title": "Interactions of divalent metal ions with inorganic and nucleoside phosphates. II. Kinetics of magnesium(II) with HP 3 O 10  4- ,ATP, CTP, HP 2 O 7  3- , ADP, and CDP.", "content": "Interactions of divalent metal ions with inorganic and nucleoside phosphates. II. Kinetics of magnesium(II) with HP 3 O 10  4- ,ATP, CTP, HP 2 O 7  3- , ADP, and CDP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345161"}
{"pmid": "4345162", "title": "Isolation and reactivation of the axostyle. Evidence for a dynein-like ATPase in the axostyle.", "content": "Isolation and reactivation of the axostyle. Evidence for a dynein-like ATPase in the axostyle. The contractile axostyle is a ribbon-shaped organelle present in certain species of flagellates found in the hindgut of wood eating insects. This organelle propagates an undulatory wave whose motion, like flagella and cilia, is related to microtubules. Unlike the axoneme of cilia and flagella, however, the axostyle is composed of singlet microtubules linked together in parallel rows. Axostyles were isolated from Cryptocercus gut protozoa with Triton X-100. Normal motility of the isolated axostyle could be restored with adenosine triphosphate (ATP); the specific conditions necessary for this reactivation were essentially identical with those reported for the reactivation of isolated flagella or whole sperm. ATPase activity of the isolated axostyle was comparable to the values reported for ciliary or flagellar axonemes. The axostyle was reasonably specific for ATP. Most of the proteins of the isolated axostyle comigrated with proteins of the ciliary axoneme on sodium dodecyl sulfate (SDS) polyacrylamide gels (i e. equivalent molecular weights). These included the following: the higher molecular weight component of dynein, tubulin, linkage protein (nexin), and various secondary proteins. Evidence for dynein in the axostyle is presented and a model proposed to explain how repeated propagated waves can be generated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345162"}
{"pmid": "4345163", "title": "Regulation of protein synthesis in the venom gland of viperid snakes.", "content": "Regulation of protein synthesis in the venom gland of viperid snakes. Morphological changes in the venom gland of V. ammodytes were studied after the removal of the venom from the gland lumina (milking) It was found that the height of the secretory cells was changed during the secretory cycle. The patterns of the rough endoplasmic reticulum and of the Golgi complex were changed as well Milking induced an increased incorporation of [(14)C]amino acids into total and venom proteins In V ammodytes, during the first day after milking, 25% of the total counts in protein were precipitable by anti-venom serum, while at 8 days, 80% of the proteins synthesized were venom proteins At this stage, the incorporation was 10- and 20-fold that of unmilked glands for total and venom proteins, respectively. Venom was accumulated (secreted) in the gland lumina of V. ammodytes at a relatively high rate up to 2 wk after milking and leveled off afterwards. Intact glands and gland slices of V ammodytes and V palaestinae, taken from snakes a few days after milking, incorporated [(14)C]amino acids into proteins in vitro at a rate higher than that of unmilked glands. The activity of two exportable enzymes (phosphodiesterase and benzoyl arginyl ethyl esterase) was assayed in gland homogenates of V. ammodytes. It was found that 2-3 wk after milking, the intracellular level of these enzymes was up to 2-fold that of unmilked glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345163"}
{"pmid": "4345164", "title": "An improved cell fractionation procedure for the preparation of rat liver membrane-bound ribosomes.", "content": "An improved cell fractionation procedure for the preparation of rat liver membrane-bound ribosomes. A cell fractionation procedure is described which allows the preparation from rat liver of a rough microsome population containing almost 50% of the membrane-bound ribosomes of the tissue. The fraction is not contaminated with free ribosomes or smooth microsomes, and, by various other criteria, is suitable for studies of ribosome-membrane interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345164"}
{"pmid": "4345165", "title": "Single strand-containing replicating molecules of circular mitochondrial DNA.", "content": "Single strand-containing replicating molecules of circular mitochondrial DNA. Mitochondrial DNAs (mtDNAs) from Chang rat solid hepatomas and Novikoff rat ascites hepatomas were examined in the electron microscope after preparation by the aqueous and by the formamide protein monolayer techniques. MtDNAs from both tumors were found to include double-forked circular molecules with a form and size suggesting they were replicative intermediates. These molecules were of two classes. In molecules of one class, all three segments were apparently totally double stranded. Molecules of the second class were distinguished by the fact that one of the segments spanning the region between the forks in which replication had occurred (the daughter segments) was either totally single stranded, or contained a single-stranded region associated with one of the forks. Daughter segments of both totally double-stranded and single strand-containing replicating molecules varied in length from about 3 to about 80% of the circular contour length of the molecule. Similar classes of replicating molecules were found in mtDNA from regenerating rat liver and chick embryos, indicating them to be normal intermediates in the replication of mtDNA All of the mtDNAs examined included partially single-stranded simple (nonforked) circular molecules. A possible scheme for the replication of mtDNA is presented, based on the different molecular forms observed", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345165"}
{"pmid": "4345166", "title": "Adenine nucleotide-induced contraction of the inner mitochondrial membrane. I. General characterization.", "content": "Adenine nucleotide-induced contraction of the inner mitochondrial membrane. I. General characterization. The inner membranes of isolated bovine heart mitochondria undergo pronounced contraction upon being exposed to exogenous adenosine diphosphate (ADP), adenosine triphosphate (ATP), and certain other high-energy phosphate compounds. Contraction results in decrease of inner membrane expanse which in turn results in decrease of intracristal space and increase of mitochondrial optical density (OD). The magnitude of the OD change appears to be proportional to the degree of contraction Half-maximal contraction can be achieved with ADP or ATP at concentrations as low as about 0 3 microM. Atractyloside at concentrations as low as about 1.2 nmol/mg mitochondrial protein completely inhibits the contraction. It is concluded from these and other observations that inner membrane contraction occurs as a result of adenine nucleotide binding to the carrier involved in the exchange of adenine nucleotides across the inner mitochondrial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345166"}
{"pmid": "4345167", "title": "Adenine nucleotide-induced contraction on the inner mitochondrial membrane. II. Effect of bongkrekic acid.", "content": "Adenine nucleotide-induced contraction on the inner mitochondrial membrane. II. Effect of bongkrekic acid. In bovine heart mitochondria bongkrekic acid at concentrations as low as about 4 nmol/mg protein (a) completely inhibits phosphorylation of exogenous adenosine diphosphate (ADP) and dephosphorylation of exogenous adenosine triphosphate (ATP), (b) completely reverses atractyloside inhibition of inner membrane contraction induced by exogenous adenine nucleotides, and (c) decreases the amount of adenine nucleotide required to elicit maximal exogenous adenine nucleotide-induced inner membrane contraction to a level which appears to correspond closely with the concentration of contractile, exogenous adenine nucleotide binding sites Bongkrekic acid at concentrations greater than 4 nmol/mg protein induces inner membrane contraction which seems to depend on the presence of endogenous ADP and/or ATP. The findings appear to be consistent with the interpretations (a) that the inner mitochondrial membrane contains two types of contractile, adenine nucleotide binding sites, (b) that the two sites differ markedly with regard to adenine nucleotide affinity, (c) that the high affinity site is identical with the adenine nucleotide exchange carrier, (d) that the low affinity site is accessible exclusively to endogenous adenine nucleotides and is largely unoccupied in the absence of bongkrekic acid, and (e) that bongkrekic acid increases the affinity of both sites in proportion to the amount of the antibiotic bound to the inner membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345167"}
{"pmid": "4345168", "title": "Role of the cerebellum in the control of gastro-intestinal motility.", "content": "Role of the cerebellum in the control of gastro-intestinal motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345168"}
{"pmid": "4345169", "title": "Effects of p-chlorophenylalanine and a monoamine oxidase inhibitor on the 5-hydroxytryptamine in the spinal cord and transection.", "content": "Effects of p-chlorophenylalanine and a monoamine oxidase inhibitor on the 5-hydroxytryptamine in the spinal cord and transection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345169"}
{"pmid": "4345171", "title": "Reovirus-induced aqueductal stenosis in hamsters. Phase contrast and electron microscopic studies.", "content": "Reovirus-induced aqueductal stenosis in hamsters. Phase contrast and electron microscopic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345171"}
{"pmid": "4345170", "title": "Disorders of growth hormone and corticotropin regulation in patients with empty sella.", "content": "Disorders of growth hormone and corticotropin regulation in patients with empty sella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345170"}
{"pmid": "4345172", "title": "The induction of thrombosis in guinea pigs by a brain tumor.", "content": "The induction of thrombosis in guinea pigs by a brain tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345172"}
{"pmid": "4345173", "title": "Storage of catecholamines in neuroblastoma and ganglioneuroma. A biochemical, immunologic, and morphologic study.", "content": "Storage of catecholamines in neuroblastoma and ganglioneuroma. A biochemical, immunologic, and morphologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345173"}
{"pmid": "4345177", "title": "Neuropathic arthropathy (Charcot forefeet) in alcoholics.", "content": "Neuropathic arthropathy (Charcot forefeet) in alcoholics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345177"}
{"pmid": "4345178", "title": "REM sleep and central monoamine oxidase inhibition.", "content": "REM sleep and central monoamine oxidase inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345178"}
{"pmid": "4345180", "title": "Observations on roentgen features of benign and malignant gastric ulcers.", "content": "Observations on roentgen features of benign and malignant gastric ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345180"}
{"pmid": "4345188", "title": "Osteoclasts and their relationship to bone as studied by electron microscopy.", "content": "Osteoclasts and their relationship to bone as studied by electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345188"}
{"pmid": "4345189", "title": "Cytoplasmic vacuoles and bodies of the osteoclast. An electron microscope study.", "content": "Cytoplasmic vacuoles and bodies of the osteoclast. An electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345189"}
{"pmid": "4345196", "title": "Regional differentiation of the axon: a review with special reference to the concept of the multiplex neuron.", "content": "Regional differentiation of the axon: a review with special reference to the concept of the multiplex neuron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345196"}
{"pmid": "4345191", "title": "The ultrastructure of oösorption in Locusta migratoria migratorioides.", "content": "The ultrastructure of oösorption in Locusta migratoria migratorioides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345191"}
{"pmid": "4345194", "title": "Juvenile nasopharyngeal angiofibroma: report of a case.", "content": "Juvenile nasopharyngeal angiofibroma: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345194"}
{"pmid": "4345192", "title": "Isolation and classification of feline picornavirus and herpesvirus in Denmark.", "content": "Isolation and classification of feline picornavirus and herpesvirus in Denmark.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345192"}
{"pmid": "4345193", "title": "Theophylline-induced hypocalcemia in sheep.", "content": "Theophylline-induced hypocalcemia in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345193"}
{"pmid": "4345197", "title": "Response patterns of single units in the olfactory bulb of the rat to odor.", "content": "Response patterns of single units in the olfactory bulb of the rat to odor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345197"}
{"pmid": "4345198", "title": "Repetitive firing in dorsal spinocerebellar tract neurones.", "content": "Repetitive firing in dorsal spinocerebellar tract neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345198"}
{"pmid": "4345200", "title": "Roentgenologic changes in hypothyroidism (a study of 40 cases).", "content": "Roentgenologic changes in hypothyroidism (a study of 40 cases).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345200"}
{"pmid": "4345190", "title": "Tissue culture of rat adult decapsulated adrenal glands. A methodological, ultrastructural and morphometric investigation.", "content": "Tissue culture of rat adult decapsulated adrenal glands. A methodological, ultrastructural and morphometric investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345190"}
{"pmid": "4345201", "title": "Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ responsiveness to parathyroid hormone, impaired parathyroid gland function.", "content": "Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ responsiveness to parathyroid hormone, impaired parathyroid gland function. Hypocalcemia is a frequent feature of hypomagnesemia in man and several other species. To elucidate the cause of this hypocalcemia, we have studied a child with primary hypomagnesemia and secondary hypocalcemia during magnesium supplementation when he was normomagnesemic and normocalcemic and after magnesium restriction for 16 days when he quickly became hypomagnesemic (0.5 meq/liter) and hypocalcemic (3.4 meq/liter) and had positive Chvostek's and Trousseau's signs. Whether in the normomagnesemic or hypomagnesemic state, intravenous bovine parathyroid extract (PTE) 8 U. S. P. U/kg promptly caused transient increases in the urinary phosphate excretion, renal phosphate clearance and cyclic AMP excretion. The magnitudes of these responses were similar in the two states, and similar to those observed in a hypoparathyroid patient. When the patient was hypomagnesemic and hypocalcemic, intramuscular PTE, 8 U/kg at 8-h intervals for four doses promptly caused hypercalcemia. The findings indicate that the end-organs were responsive to parathyroid hormone. The concentrations of serum parathyroid hormone (PTH) were normal in the normomagnesemic state ranging from 0.15 ng/ml to 0.40 ng/ml. Serum PTH did not increase in the hypomagnesemic state in spite of hypocalcemia. Indeed, PTH became unmeasurable in four consecutive samples at the end of the period of magnesium restriction. The concentrations of serum calcitonin remained unmeasurable (< 0.10 ng/ml) throughout the study, implying that excess calcitonin was not the cause of hypocalcemia in magnesium depletion. The findings in this study support our thesis that magnesium depletion causes impaired synthesis or secretion of parathyroid hormone. This impairment would account for the hypocalcemia observed in the hypomagnesemic state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345201"}
{"pmid": "4345202", "title": "Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man.", "content": "Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man. Apolipoproteins of the \"C\" group in human blood plasma, which contain the activator of the lipoprotein lipase-substrate interaction, were found to be transferred specifically from serum to phospholipid-stabilized fat emulsion. Content and distribution of apoprotein activator were measured in healthy men in the postabsorptive state and 4 h after ingestion of meals containing 100 g fat. Content of activator protein in whole serum did not change after ingestion of the fat-rich meals but that contained in triglyceride-rich lipoproteins of density (d) <1.006 approximately doubled whereas that of high density lipoproteins fell by half. The increased activator content of triglyceride-rich lipoproteins was virtually confined to chylomicrons and its concentration in chylomicron apoprotein was substantially greater than that in very low density lipoproteins. This difference could be ascribed largely to a higher content of C apoproteins in chylomicron protein since both the concentration of C apoproteins and of apoprotein activator were directly proportional to particle diameter while the pattern of fast-migrating C apoproteins in polyacrylamide gels was similar among chylomicrons and subfractions of very low density lipoproteins. Apparent concentration of activator protein was much greater in the high density lipoprotein subfraction of d 1.063-1.125 than in the subfraction of d 1.125-1.21. In the subfraction of d 1.063-1.125, the concentration of activator protein and of fast-migrating C apoproteins in polyacrylamide gels decreased after the fat-rich meal. Concentration of phospholipids in this fraction increased gradually to a peak 43% above the basal value 6 h after the meal. The results obtained demonstrate that high density lipoproteins contribute certain functionally important polar constituents to chylomicrons during alimentary lipemia in man and suggest that they also receive surface constituents from chylomicrons during the course of their metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345202"}
{"pmid": "4345203", "title": "Estrogen receptors in human breast cancer.", "content": "Estrogen receptors in human breast cancer. Specific quantitative techniques have been used to measure the cytoplasmic estradiol-binding protein (EBP) in human mammary carcinoma tissue specimens. Sucrose gradient centrifugation reveals EBP to sediment at 8S and 4S. Variable quantities of non-specific estradiol binding occurs in the 4S region of the sucrose gradient necessitating controls to insure specificity of the estradiol protein interaction. Using dextran-coated charcoal to separate bound from free estradiol Scatchard analysis finds the dissociation constant of the estradiol EBP interaction to be approximately 2.6x10(-10) M, indicative of the very high affinity of the ligand for the EBP. Quantitation of EBP sites in 64 primary and metastatic human breast tumors demonstrates a continuous spectrum of values from 0 to 612 fmol per mg of cytoplasmic protein. Specific 8S binding in the sucrose gradient centrifugation was not detected in specimens containing less than 9.0 fmol EBP per mg cytoplasmic protein. Since data from animal breast tumors and preliminary evidence from human breast tumors indicates an excellent correlation between the presence of abundant tumor EBP and endocrine-induced breast cancer regressions, precise quantitation of EBP in all human primary tumors may prove to be an excellent prognosticator of endocrine therapy in metastatic breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345203"}
{"pmid": "4345206", "title": "Pseudopodia formation by secretory granules.", "content": "Pseudopodia formation by secretory granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345206"}
{"pmid": "4345208", "title": "Characteristics of two strains of avian sarcoma virus B77.", "content": "Characteristics of two strains of avian sarcoma virus B77.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345208"}
{"pmid": "4345207", "title": "Cyclic adenosine monophosphate-mediated stabilization of mouse neuroblastoma cell neuritis microtubules exposed to low temperature.", "content": "Cyclic adenosine monophosphate-mediated stabilization of mouse neuroblastoma cell neuritis microtubules exposed to low temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345207"}
{"pmid": "4345209", "title": "Clonal analysis of RBI rat tumour cells producing chicken sarcoma virus.", "content": "Clonal analysis of RBI rat tumour cells producing chicken sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345209"}
{"pmid": "4345211", "title": "On the presence of ribosome-like particles in avian myeloblastosis virions (AMV) and unusual ultrastructure of their nucleoid.", "content": "On the presence of ribosome-like particles in avian myeloblastosis virions (AMV) and unusual ultrastructure of their nucleoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345211"}
{"pmid": "4345212", "title": "Toward control of tumour and virus growth by helical RNA. I. Effect of poly I:C on tumour transplantation resistance in animals bearing tumours of viral and non-viral origin.", "content": "Toward control of tumour and virus growth by helical RNA. I. Effect of poly I:C on tumour transplantation resistance in animals bearing tumours of viral and non-viral origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345212"}
{"pmid": "4345210", "title": "Different tumorigenicity of avian RNA sarcoma viruses for some mammalian species.", "content": "Different tumorigenicity of avian RNA sarcoma viruses for some mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345210"}
{"pmid": "4345214", "title": "Polynucleotidases in mouse ascitic tumour cells.", "content": "Polynucleotidases in mouse ascitic tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345214"}
{"pmid": "4345213", "title": "Inactivation of papovavirus SV 40 by cis-dichlorodiammine platinum(II).", "content": "Inactivation of papovavirus SV 40 by cis-dichlorodiammine platinum(II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345213"}
{"pmid": "4345218", "title": "Non beta cell tumors of the pancreas. A review with report of four cases.", "content": "Non beta cell tumors of the pancreas. A review with report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345218"}
{"pmid": "4345219", "title": "Effects of norepinephrine, angiotensin, dihydroergotamine, papaverine, isoproterenol, histamine, nicotinic acid, and xanthinol nicotinate on retinal oxygen tension in cats.", "content": "Effects of norepinephrine, angiotensin, dihydroergotamine, papaverine, isoproterenol, histamine, nicotinic acid, and xanthinol nicotinate on retinal oxygen tension in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345219"}
{"pmid": "4345229", "title": "Enzyme activity patterns in gas gland tissue of the swimbladder of the cod (Gadus morrhua).", "content": "Enzyme activity patterns in gas gland tissue of the swimbladder of the cod (Gadus morrhua).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345229"}
{"pmid": "4345230", "title": "The development of lipolytic sensitivity in the isolated fat cells of Gallus domesticus during the foetal and neonatal period.", "content": "The development of lipolytic sensitivity in the isolated fat cells of Gallus domesticus during the foetal and neonatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345230"}
{"pmid": "4345233", "title": "Enzyme markers: their linkage with proteins and use in immuno-histochemistry.", "content": "Enzyme markers: their linkage with proteins and use in immuno-histochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345233"}
{"pmid": "4345237", "title": "Potentiation of phenothiazines by  -methyltyrosine in treatment of chronic schizophrenia.", "content": "Potentiation of phenothiazines by  -methyltyrosine in treatment of chronic schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345237"}
{"pmid": "4345239", "title": "Cytomegalovirus infection in a newborn dizygous twin.", "content": "Cytomegalovirus infection in a newborn dizygous twin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345239"}
{"pmid": "4345238", "title": "Effect of methionine on liver lipid content and lipid metabolism of rats fed a protein-free diet.", "content": "Effect of methionine on liver lipid content and lipid metabolism of rats fed a protein-free diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345238"}
{"pmid": "4345240", "title": "Wilms' tumor in the newborn period.", "content": "Wilms' tumor in the newborn period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345240"}
{"pmid": "4345242", "title": "Mechanism of noradrenaline action in cat cerebral cortex.", "content": "Mechanism of noradrenaline action in cat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345242"}
{"pmid": "4345241", "title": "Discontinuous DNA replication in vitro. I. Two distinct size classes of intermediates.", "content": "Discontinuous DNA replication in vitro. I. Two distinct size classes of intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345241"}
{"pmid": "4345243", "title": "Size requirement of polyinosinic acid for DNA synthesis, viral resistance, and increased survival of leukaemic mice.", "content": "Size requirement of polyinosinic acid for DNA synthesis, viral resistance, and increased survival of leukaemic mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345243"}
{"pmid": "4345244", "title": "Regulation of normal and leukaemic lymphocyte transformation and recirculation by sodium periodate oxidation and sodium borohydride reduction.", "content": "Regulation of normal and leukaemic lymphocyte transformation and recirculation by sodium periodate oxidation and sodium borohydride reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345244"}
{"pmid": "4345246", "title": "Photoreaction of FMN-tricine and its participation in photophosphorylation.", "content": "Photoreaction of FMN-tricine and its participation in photophosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345246"}
{"pmid": "4345247", "title": "Characterisation of staphylococci isolated from poultry.", "content": "Characterisation of staphylococci isolated from poultry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345247"}
{"pmid": "4345249", "title": "Intestinal alkaline phosphatase and phytase of chicks: effect of dietary magnesium, calcium, phosphorus and thyroactive casein.", "content": "Intestinal alkaline phosphatase and phytase of chicks: effect of dietary magnesium, calcium, phosphorus and thyroactive casein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345249"}
{"pmid": "4345250", "title": "The effect of vitamin A on tumour development and regression in chickens infected with Marek's disease and Rous sarcoma virus.", "content": "The effect of vitamin A on tumour development and regression in chickens infected with Marek's disease and Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345250"}
{"pmid": "4345248", "title": "Properties of chick intestinal phytase.", "content": "Properties of chick intestinal phytase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345248"}
{"pmid": "4345257", "title": "Electron microscopic study on nuclear changes in multiple sclerosis brain biopsies.", "content": "Electron microscopic study on nuclear changes in multiple sclerosis brain biopsies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345257"}
{"pmid": "4345256", "title": "On the phosphorylation of Escherichia coli ribosomes. II. Reaction in cell-free system.", "content": "On the phosphorylation of Escherichia coli ribosomes. II. Reaction in cell-free system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345256"}
{"pmid": "4345258", "title": "Electron microscopic studies of rabbit central and peripheral nervous system in experimental Borna disease.", "content": "Electron microscopic studies of rabbit central and peripheral nervous system in experimental Borna disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345258"}
{"pmid": "4345259", "title": "Effect of TOCP poisoning on the Pacinian corpuscles of slow loris.", "content": "Effect of TOCP poisoning on the Pacinian corpuscles of slow loris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345259"}
{"pmid": "4345260", "title": "Age determination of swine foetuses.", "content": "Age determination of swine foetuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345260"}
{"pmid": "4345262", "title": "Aspergillosis complicating neoplastic disease.", "content": "Aspergillosis complicating neoplastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345262"}
{"pmid": "4345261", "title": "Recent contributions to the study of diabetic angiopathy and neuropathy.", "content": "Recent contributions to the study of diabetic angiopathy and neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345261"}
{"pmid": "4345263", "title": "Low molecular weight glycogen as a cause of generalized glycogen storage disease.", "content": "Low molecular weight glycogen as a cause of generalized glycogen storage disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345263"}
{"pmid": "4345264", "title": "Unilateral total renal dysplasia in children.", "content": "Unilateral total renal dysplasia in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345264"}
{"pmid": "4345265", "title": "Disappearance of disseminated pancreatic carcinoma with combined chemotherapy.", "content": "Disappearance of disseminated pancreatic carcinoma with combined chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345265"}
{"pmid": "4345266", "title": "Angiotensin-receptor interaction: influence of pH on angiotensin inhibition by Phe 4 -Tyr 8 -angiotensin II in rat uterine smooth muscle.", "content": "Angiotensin-receptor interaction: influence of pH on angiotensin inhibition by Phe 4 -Tyr 8 -angiotensin II in rat uterine smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345266"}
{"pmid": "4345268", "title": "Factors affecting cholesterol esterase and cholesterol side-chain-cleavage activities in rat adrenal.", "content": "Factors affecting cholesterol esterase and cholesterol side-chain-cleavage activities in rat adrenal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345268"}
{"pmid": "4345269", "title": "The synthesis of beta corticotrophin-(1-24)-tetracosapeptide (synacthen) of high specific radioactivity.", "content": "The synthesis of beta corticotrophin-(1-24)-tetracosapeptide (synacthen) of high specific radioactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345269"}
{"pmid": "4345270", "title": "Observations on the fate of adrenocorticotrophin in isolated rat adrenal-cell suspensions and the separation of an enriched adrenocorticotrophin-sensitive steroidogenic cell fraction.", "content": "Observations on the fate of adrenocorticotrophin in isolated rat adrenal-cell suspensions and the separation of an enriched adrenocorticotrophin-sensitive steroidogenic cell fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345270"}
{"pmid": "4345271", "title": "Structure-activity relations for the nicotinamide-adenine-dinucleotide-linked 3-hydroxysteroid oxidoreductase activity of cortisone reductase with special reference to the ring A-B junction and ring D.", "content": "Structure-activity relations for the nicotinamide-adenine-dinucleotide-linked 3-hydroxysteroid oxidoreductase activity of cortisone reductase with special reference to the ring A-B junction and ring D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345271"}
{"pmid": "4345272", "title": "Structure-activity relations for the nicotinamide-adenine dinucleotide-linked 20beta-hydroxysteroid oxidoreductase activity of cortisone reductase with special reference to ring B.", "content": "Structure-activity relations for the nicotinamide-adenine dinucleotide-linked 20beta-hydroxysteroid oxidoreductase activity of cortisone reductase with special reference to ring B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345272"}
{"pmid": "4345273", "title": "Insulin release from mouse islets. Effect of glucose and hormones on adenylate cyclase.", "content": "Insulin release from mouse islets. Effect of glucose and hormones on adenylate cyclase. The adenylate cyclase system of normal mouse islets was characterized. The pH optimum of the system was 7.6. The enzyme preparation contained particulate phosphodiesterase activity. This could be removed by treatment with 0.4% (v/v) Triton X-100 or inhibited by 8mm-theophylline in the presence of 2mm-cyclic AMP (adenosine 3':5'-cyclic monophosphate). ATP at 0.32mm produced one-half maximal enzyme activity. The enzyme was stimulated in the presence of F(-) and strongly inhibited by Ca(2+). The isolated enzyme retained hormonal sensitivity and was stimulated by glucagon, pancreozymin and secretin at physiological concentrations. Glucose at 17mm, 8mm and 2mm had no direct effect on the activity of the enzyme; neither did galactose at the same concentrations. Groups of islets incubated in 17mm- or 2mm-glucose for 5 or 15min and then homogenized and assayed for adenylate cyclase activity showed no differences in adenylate cyclase activity. The results suggest that the mechanism of glucose-mediated insulin release is not via the adenylate cyclase system. Hormones, however, could mediate insulin secretion via their effects on the adenylate cyclase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345273"}
{"pmid": "4345274", "title": "Microbial metabolism of alkylbenzene sulphonates. Bacterial metabolism of undecylbenzene-p-sulphonate and dodecylbenzene-p-sulphonate.", "content": "Microbial metabolism of alkylbenzene sulphonates. Bacterial metabolism of undecylbenzene-p-sulphonate and dodecylbenzene-p-sulphonate. 1. A study was made of the biodegradation of alkylbenzene sulphonate homologues, one of the major components of commercially marketed detergents. A Bacillus species was elected for growth on alkylbenzene sulphonate homologues as the sole source of carbon and sulphur. 2. The results from both whole-cell and cell-free systems indicated that the alkyl, aryl and sulphonate moieties of alkylbenzene sulphonate homologues were all further metabolized by the Bacillus species. 3. The alkyl side chain, after a presumed initial oxidation of the terminal methyl group, was subsequently oxidized by a beta-oxidation pathway. Three enzymes of the beta-oxidation pathway, i.e. acyl-CoA synthetase, acyl-CoA dehydrogenase and beta-hydroxyacyl-CoA dehydrogenase, were identified in cell-free extracts of the detergent-grown Bacillus species. The substrate specificity of acyl-CoA synthetase indicated activity towards several alkylbenzene sulphonate homologues. 4. The sulphonate moiety was released as sulphite by a desulphonating enzyme. Some kinetic properties of this enzyme were determined. The sulphite was subsequently metabolized to either sulphate or adenosine 5'-sulphatophosphate. Two enzymes involved in sulphite metabolism, i.e. sulphite-cytochrome c reductase and adenosine 5'-sulphatophosphate-cytochrome c reductase were detected in cell-free extracts of undecylbenzene-p-sulphonate-grown Bacillus species. 5. The combined results of continuous sampling programmes monitored by both t.l.c. and sulphite appearance in the growth medium indicated that desulphonation of the aromatic moiety was the likely first step in the overall biodegradation of several alkylbenzene sulphonate homologues. 6. The presence of p-hydroxyphenylpropionate, p-hydroxybenzoate and 3,4-dihydroxybenzoate in cells after growth on several alkylbenzene sulphonate homologues containing an odd number of carbon atoms in the side chain was confirmed by g.l.c. and t.l.c. analysis. Cells grown on several homologues containing an even number of carbon atoms in the side chain were shown to contain p-hydroxyphenylacetate and 3,4-dihydroxyphenylacetate. 7. The aromatic nucleus obtained from undecylbenzene-p-sulphonate was further metabolized by an oxidation sequence involving an ;ortho-cleavage' route. 8. An overall metabolic pathway for the biodegradation of various alkylbenzene sulphonate homologues by this Bacillus species is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345274"}
{"pmid": "4345275", "title": "The role of histidine residues in glutamate dehydrogenase.", "content": "The role of histidine residues in glutamate dehydrogenase. 1. Glutamate dehydrogenase was subject to rapid inactivation when irradiated in the presence of Rose Bengal or incubated in the presence of ethoxyformic anhydride. 2. Inactivation in the presence of Rose Bengal led to the photo-oxidation of four histidine residues. Oxidation of three histidine residues had little effect on enzyme activity, but oxidation of the fourth residue led to the almost total loss of activity. 3. Acylation of glutamate dehydrogenase with ethoxyformic anhydride at pH6.1 led to the modification of three histidine residues with a corresponding loss of half the original activity. Acylation at pH7.5 led to the modification of two histidine residues and a total loss of enzyme activity. 4. One of the histidine residues undergoing reaction at pH6.1 also undergoes reaction at pH7.5. 5. The presence of either glutamate or NAD(+) in the reaction mixtures at pH6.1 had no appreciable effect. At pH7.5 glutamate caused a marked decrease in both the degree of alkylation and degree of inactivation. NAD(+) had no effect on the degree of inactivation at pH7.5 but did modify the extent of acylation. 6. The normal response of the enzyme towards ADP was unaffected by acylation at pH6.1 or 7.5. 7. The normal response of the enzyme towards GTP was altered by treatment at both pH6.1 and 7.5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345275"}
{"pmid": "4345278", "title": "The mode of adrenocorticotrophin action in stimulating steroidogenesis: the obligatory role of adenosine 3':5'-cyclic monophosphate and the involvement of rapidly-turning-over protein.", "content": "The mode of adrenocorticotrophin action in stimulating steroidogenesis: the obligatory role of adenosine 3':5'-cyclic monophosphate and the involvement of rapidly-turning-over protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345278"}
{"pmid": "4345277", "title": "The location of adrenocorticotrophin receptors in the adrenal cortex.", "content": "The location of adrenocorticotrophin receptors in the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345277"}
{"pmid": "4345276", "title": "Studies on the light-dependent synthesis of inorganic pyrophosphate by Rhodospirillum rubrum chromatophores.", "content": "Studies on the light-dependent synthesis of inorganic pyrophosphate by Rhodospirillum rubrum chromatophores. Characteristics of inorganic pyrophosphate synthesis from inorganic orthophosphate were examined in chromatophores of Rhodospirillum rubrum. The application of an ADP-glucose pyrophosphorylase-trapping system has shown in an unequivocal fashion that pyrophosphate is a product of a light-dependent reaction utilizing P(i) as the substrate. Only very limited pyrophosphate synthesis takes place in the dark. The rates of synthesis of both ATP and pyrophosphate were studied under conditions in which the membrane-bound adenosine triphosphatase and pyrophosphatase activities would normally make these substances unstable. The maximum rate of pyrophosphate synthesis was 25% of that for ATP synthesis, with maximum activation of pyrophosphate synthesis occurring at a lower light-intensity than that required for ATP synthesis. As a result, at low light-intensity the rate of pyrophosphate formation approached that of ATP. Maximal rates of synthesis of both pyrophosphate and ATP were attained only on the addition of an exogenous reducing agent. Conditions for optimum pyrophosphate synthesis required about one-half of the concentration of the reductant required for maximum ATP synthesis. Consistent with previous reports, oligomycin inhibited ATP synthesis, but had little influence on the rate of pyrophosphate synthesis. In membrane particles that retained pyrophosphatase activity but were treated to remove adenosine triphosphatase activity and the ability to photophosphorylate ADP, oligomycin stimulated light-dependent pyrophosphate synthesis by nearly 250%. The influence of Mg(2+) concentration, pH and various inhibitors and uncouplers on pyrophosphate synthesis was studied. The results are discussed with respect to the mechanism and function of electron-transport-coupled energy conservation in R. rubrum chromatophores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345276"}
{"pmid": "4345279", "title": "The effect of adrenocorticotrophin in vivo on pregnenolone synthesis by adrenal mitochondria.", "content": "The effect of adrenocorticotrophin in vivo on pregnenolone synthesis by adrenal mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345279"}
{"pmid": "4345280", "title": "The I-O-galactosylceramide fatty acid esters from hog stomach.", "content": "The I-O-galactosylceramide fatty acid esters from hog stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345280"}
{"pmid": "4345281", "title": "Metabolism of prostaglandin F 1   in the guinea pig.", "content": "Metabolism of prostaglandin F 1   in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345281"}
{"pmid": "4345282", "title": "The effects on cytochrome b-559HP and P546 of treatments that inhibit oxygen evolution by chloroplasts.", "content": "The effects on cytochrome b-559HP and P546 of treatments that inhibit oxygen evolution by chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345282"}
{"pmid": "4345283", "title": "Oxidative phosphorylation in yeast. X. Phosphorylation ability of mutants deficient in cytochromes a and b.", "content": "Oxidative phosphorylation in yeast. X. Phosphorylation ability of mutants deficient in cytochromes a and b.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345283"}
{"pmid": "4345285", "title": "Conformation changes in cytochrome oxidase as studied by sedimentation difference.", "content": "Conformation changes in cytochrome oxidase as studied by sedimentation difference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345285"}
{"pmid": "4345284", "title": "Solubilization and purification of cytochrome   1  from Nitrosomonas.", "content": "Solubilization and purification of cytochrome   1  from Nitrosomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345284"}
{"pmid": "4345286", "title": "Biochemical and biophysical studies on cytochrome aa 3 . IX. Reaction of cytochrome aa 3  with hydrazine.", "content": "Biochemical and biophysical studies on cytochrome aa 3 . IX. Reaction of cytochrome aa 3  with hydrazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345286"}
{"pmid": "4345288", "title": "Some peculiarities of the steady-state kinetics of electron transfer in submitochondrial particles. A kinetic model based on the idea of activation on the respiratory chain induced by electron transfer.", "content": "Some peculiarities of the steady-state kinetics of electron transfer in submitochondrial particles. A kinetic model based on the idea of activation on the respiratory chain induced by electron transfer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345288"}
{"pmid": "4345287", "title": "Reduction and oxidation of longer-wavelength cytochrome b (b 566 ) in rat liver mitochondria under the influence of external oxidants.", "content": "Reduction and oxidation of longer-wavelength cytochrome b (b 566 ) in rat liver mitochondria under the influence of external oxidants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345287"}
{"pmid": "4345294", "title": "Phenytoin treatment of thalamic pain.", "content": "Phenytoin treatment of thalamic pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345294"}
{"pmid": "4345296", "title": "Anticholinergic action of aminophylline in isolated guinea-pig atria.", "content": "Anticholinergic action of aminophylline in isolated guinea-pig atria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345296"}
{"pmid": "4345295", "title": "Studies on the mechanism of activation and deactivation of histidine decarboxylase.", "content": "Studies on the mechanism of activation and deactivation of histidine decarboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345295"}
{"pmid": "4345297", "title": "Effects of a carbodiimide on neuromuscular transmission in frog.", "content": "Effects of a carbodiimide on neuromuscular transmission in frog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345297"}
{"pmid": "4345298", "title": "Mechanism of noradrenaline depression of cortical neurones: a species comparison.", "content": "Mechanism of noradrenaline depression of cortical neurones: a species comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345298"}
{"pmid": "4345299", "title": "Lysosomal hydrolase alterations in the postphagocytic liver.", "content": "Lysosomal hydrolase alterations in the postphagocytic liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345299"}
{"pmid": "4345305", "title": "Intestinal helminths in inbred strains of mice.", "content": "Intestinal helminths in inbred strains of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345305"}
{"pmid": "4345303", "title": "Methods of anesthesia in nonhuman primates.", "content": "Methods of anesthesia in nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345303"}
{"pmid": "4345302", "title": "Demonstration of adenosin 3',5'-monophosphate dependent protein-phosphokinase in human platelets.", "content": "Demonstration of adenosin 3',5'-monophosphate dependent protein-phosphokinase in human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345302"}
{"pmid": "4345304", "title": "The pathology and pathogenesis of Bordetella bronchiseptica and Pasteurella pneumotropica infection in conventional and germfree rats.", "content": "The pathology and pathogenesis of Bordetella bronchiseptica and Pasteurella pneumotropica infection in conventional and germfree rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345304"}
{"pmid": "4345306", "title": "Pulmonary function measurements of large animals using the capacitance respirometer.", "content": "Pulmonary function measurements of large animals using the capacitance respirometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345306"}
{"pmid": "4345307", "title": "An evaluation of the effects of various degrees of long-term confinement on adult beagle dogs.", "content": "An evaluation of the effects of various degrees of long-term confinement on adult beagle dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345307"}
{"pmid": "4345309", "title": "Dissociative anesthesia in dogs and primates: clinical evaluation of CI 744.", "content": "Dissociative anesthesia in dogs and primates: clinical evaluation of CI 744.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345309"}
{"pmid": "4345308", "title": "A diagnostic skin test for encephalitozoonosis (nosematosis) in rabbits.", "content": "A diagnostic skin test for encephalitozoonosis (nosematosis) in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345308"}
{"pmid": "4345310", "title": "Induced aortic insufficiency in the canine. The tearing of a semilunar cusp for the study of experimental endocarditis.", "content": "Induced aortic insufficiency in the canine. The tearing of a semilunar cusp for the study of experimental endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345310"}
{"pmid": "4345311", "title": "A restraint system for squirrel monkeys.", "content": "A restraint system for squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345311"}
{"pmid": "4345312", "title": "Induction of methoxyflurane anesthesia in the rabbit after ketamine hydrochloride and endotracheal intubation.", "content": "Induction of methoxyflurane anesthesia in the rabbit after ketamine hydrochloride and endotracheal intubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345312"}
{"pmid": "4345313", "title": "Design for a chronic right ventricular catheter for dogs.", "content": "Design for a chronic right ventricular catheter for dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345313"}
{"pmid": "4345314", "title": "Use of ketamine hybrochloride as an anesthetic in laboratory rabbits, rats, mice, and guinea pigs.", "content": "Use of ketamine hybrochloride as an anesthetic in laboratory rabbits, rats, mice, and guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345314"}
{"pmid": "4345315", "title": "A safe and versatile rabbit restrainer.", "content": "A safe and versatile rabbit restrainer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345315"}
{"pmid": "4345316", "title": "Nymphal Porocephalus clavatus in the brain of a squirrel monkey, Saimiri sciureus.", "content": "Nymphal Porocephalus clavatus in the brain of a squirrel monkey, Saimiri sciureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345316"}
{"pmid": "4345317", "title": "Traumatic pericarditis in a miniature pig.", "content": "Traumatic pericarditis in a miniature pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345317"}
{"pmid": "4345318", "title": "A method of bandaging queens to prevent nursing by newborn kittens until blood samples are collected.", "content": "A method of bandaging queens to prevent nursing by newborn kittens until blood samples are collected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345318"}
{"pmid": "4345319", "title": "A versatile liquid diet for nonhuman primates.", "content": "A versatile liquid diet for nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345319"}
{"pmid": "4345320", "title": "Scleral dermoid in a guinea pig.", "content": "Scleral dermoid in a guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345320"}
{"pmid": "4345321", "title": "A simple apparatus for inducing and maintaining halothane anesthesia of the rabbit.", "content": "A simple apparatus for inducing and maintaining halothane anesthesia of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345321"}
{"pmid": "4345322", "title": "A mixture for chemical restraint in the dog.", "content": "A mixture for chemical restraint in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345322"}
{"pmid": "4345326", "title": "The effect of non-nicotinic drugs on the cat's adrenal medulla during block by nicotine.", "content": "The effect of non-nicotinic drugs on the cat's adrenal medulla during block by nicotine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345326"}
{"pmid": "4345327", "title": "Effects of some inhibitors of phosphodiesterase on neuromuscular transmission.", "content": "Effects of some inhibitors of phosphodiesterase on neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345327"}
{"pmid": "4345328", "title": "Calcium metabolism in tumors--its relationship with chromium complex accumulation. V. The interaction nucleic acid-calcium and the calcification of tumors.", "content": "Calcium metabolism in tumors--its relationship with chromium complex accumulation. V. The interaction nucleic acid-calcium and the calcification of tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345328"}
{"pmid": "4345330", "title": "Genetic control of susceptibility to the avian leukosis complex. I. The leukosis-sarcoma virus group.", "content": "Genetic control of susceptibility to the avian leukosis complex. I. The leukosis-sarcoma virus group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345330"}
{"pmid": "4345329", "title": "Erythrocyte lipids in childhood.", "content": "Erythrocyte lipids in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345329"}
{"pmid": "4345331", "title": "Changes in fowl plasma  -lipoproteins caused by starvation.", "content": "Changes in fowl plasma  -lipoproteins caused by starvation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345331"}
{"pmid": "4345333", "title": "Cortisol, growth hormone response, and pain following tetracosactrin depot and ACTH gel.", "content": "Cortisol, growth hormone response, and pain following tetracosactrin depot and ACTH gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345333"}
{"pmid": "4345335", "title": "Independent effects of maternal age and birth order on the incidence of selected congenital malformations.", "content": "Independent effects of maternal age and birth order on the incidence of selected congenital malformations. Incidence rates, specific for maternal age and birth order, were calculated for 16 categories of congenital malformations reported on birth certificates from a population of more than 8 million registered, white, single livebirths.  With maternal age held constant, none of the malformations showed increasing incidence as birth order increased.  Hypospadias, esophageal defects, omphalocele, and Down syndrome showed evidence of decreasing incidence as birth order increased.  Some of the other malformation categories showed an excess of 1st births in most age groups, while no relation to birth order was observed in the incidence of other malformations.  By contrast, most of the malformations analyzed exhibited increasing incidence as maternal age increased.  Especially high rates of several malformations were observed among 1st births to women over age 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345335"}
{"pmid": "4345336", "title": "The production of congenital malformations using tissue antisera. XI. Antisera to acellular visceral yolk sac.", "content": "The production of congenital malformations using tissue antisera. XI. Antisera to acellular visceral yolk sac.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345336"}
{"pmid": "4345337", "title": "Malignant tumors arising de novo in immunosuppressed organ transplant recipients.", "content": "Malignant tumors arising de novo in immunosuppressed organ transplant recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345337"}
{"pmid": "4345341", "title": "A method for aging the female Os pubis.", "content": "A method for aging the female Os pubis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345341"}
{"pmid": "4345340", "title": "Seroepidemiologic studies of herpesvirus type 2 and carcinoma of the cervix. 3. Houston, Texas.", "content": "Seroepidemiologic studies of herpesvirus type 2 and carcinoma of the cervix. 3. Houston, Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345340"}
{"pmid": "4345342", "title": "Misapplication to females of the standard for aging the male Os pubis.", "content": "Misapplication to females of the standard for aging the male Os pubis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345342"}
{"pmid": "4345343", "title": "The in vivo development of the hamster periodontium and implications for the chin's evolution.", "content": "The in vivo development of the hamster periodontium and implications for the chin's evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345343"}
{"pmid": "4345344", "title": "Lansing man: a half century later.", "content": "Lansing man: a half century later.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345344"}
{"pmid": "4345345", "title": "Individualized predictive index for cancer of the rectum and colon.", "content": "Individualized predictive index for cancer of the rectum and colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345345"}
{"pmid": "4345346", "title": "Tubular apocrine adenoma.", "content": "Tubular apocrine adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345346"}
{"pmid": "4345347", "title": "Defects and deficiency of adenyl cyclase in psoriatic skin.", "content": "Defects and deficiency of adenyl cyclase in psoriatic skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345347"}
{"pmid": "4345348", "title": "Surface characteristics of SV40 transformed transplantable and non-transplantable mouse cells.", "content": "Surface characteristics of SV40 transformed transplantable and non-transplantable mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345348"}
{"pmid": "4345349", "title": "Comparison of mammalian mitochondrial ribosomal ribonucleic acid from different species.", "content": "Comparison of mammalian mitochondrial ribosomal ribonucleic acid from different species. Mitochondrial ribosomal RNA species from mouse L cells, rat liver, rat hepatoma, hamster BHK-21 cells and human KB cells were examined by electrophoresis on polyacrylamide-agarose gels and sedimentation in sucrose density gradients. The S(E) (electrophoretic mobility) and S values of mitochondrial rRNA of all species were highly dependent on temperature and ionic strength of the medium; the S(E) values increased and the S values decreased with an increase in temperature at a low ionic strength. At an ionic strength of 0.3 at 23-25 degrees C or an ionic strength of 0.01 at 3-4 degrees C the S and S(E) values were almost the same being about 16.2-18.0 and 12.3-13.6 for human and mouse mitochondrial rRNA. The molecular weights under these conditions were calculated to be 3.8x10(5)-4.3x10(5) and 5.9x10(5)-6.8x10(5), depending on the technique used. At 25 degrees C in buffers of low ionic strength mouse mitochondrial rRNA species had a lower electrophoretic mobility than those of human and hamster. Under these conditions the smaller mitochondrial rRNA species of hamster had a lower electrophoretic mobility than that of human but the larger component had an identical mobility. Mouse and rat mitochondrial rRNA species had identical electrophoretic mobilities. Complex differences between human and mouse mitochondrial rRNA species were observed on sedimentation in sucrose density gradients under various conditions of temperature and ionic strength. Mouse L-cell mitochondrial rRNA was eluted after cytoplasmic rRNA on a column of methylated albumin-kieselguhr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345349"}
{"pmid": "4345350", "title": "The utilization of iron and its complexes by mammalian mitochondria.", "content": "The utilization of iron and its complexes by mammalian mitochondria. Sonicated mitochondria catalyse the reduction of ferric salts, and the subsequent incorporation of Fe(2+) into haem, when provided with a reducing substrate such as succinate or NADH. The rate of haem synthesis was low under aerobic conditions and, after a short lag period, accelerated once anaerobic conditions were achieved; it was insensitive to antimycin A. The lag period was decreased by preincubating the mitochondria with NADH and Fe(3+). Newly formed Fe(2+) was autoxidized rapidly and the consequent O(2) uptake was measured with an oxygen electrode to determine the rate of enzymic formation of Fe(2+) from FeCl(3); this reaction was rapid in sonicated mitochondria provided with NADH or succinate and was insensitive to antimycin A. The reaction was very slow in intact mitochondria, suggesting a permeability barrier to Fe(3+) ions. This system was used to test the permeability of the mitochondrial membrane to various iron complexes of biological importance. Of the compounds tested only ferrioxamine G appeared to penetrate readily and the iron of this complex was reduced when intact mitochondria were supplied with succinate or NADH-linked substrates. The reduction was insensitive to rotenone or antimycin A. Both ferrioxamine G and ferrioxamine B were, however, reduced by particles. The membrane fraction of sonicated mitochondria was necessary for the reduction. The rate of ferrioxamine B reduction by sonicated mitochondria was measured by a dual-wavelength spectrophotometric assay and was found to be stimulated in conditions where the Fe(2+) produced was utilized for haem synthesis. The addition of FeCl(3) to anaerobic particles caused an oxidation of cytochrome b when this region of the respiratory chain was isolated by treatment with rotenone and antimycin A. These results suggest that the reduction of ferric iron and its complexes occurs inside the inner mitochondrial membrane in proximity to ferrochelatase. Possible sites for this reduction are the flavoproteins, succinate and NADH dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345350"}
{"pmid": "4345352", "title": "Coproporphyrinogenase activities in extracts of Rhodopseudomonas spheroides and Chromatium strain D.", "content": "Coproporphyrinogenase activities in extracts of Rhodopseudomonas spheroides and Chromatium strain D. 1. The anaerobic coproporphyrinogenase activity in an extract of Rhodopseudomonas spheroides is inhibited by 1,10-phenanthroline, alphaalpha'-bipyridyl, flavins, 2,4-dinitrophenol and 1,4-naphthaquinone. These compounds have no effect on the aerobic coproporphyrinogenase activity. 2. On removal of small-molecular-weight material from a crude extract, the anaerobic system becomes very unstable; it can be stabilized by adding succinate. Now nicotinamide nucleotides, in addition to Mg(2+), ATP and methionine, are required for protoporphyrin to be formed. 3. A mechanism for the anaerobic reaction is proposed, based on the cofactor requirements and the effect of inhibitors. 4. The enzyme responsible for aerobic activity has been partially purified and some of its properties are reported. 5. A crude extract of Chromatium strain D also exhibits coproporphyrinogenase activity under anaerobic conditions in the presence of S-adenosylmethionine or ATP plus methionine. The requirement for other cofactors is variable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345352"}
{"pmid": "4345353", "title": "The cytochromes of mitochondria from Tetrahymena pyriformis strain ST.", "content": "The cytochromes of mitochondria from Tetrahymena pyriformis strain ST. 1. Mitochondria of the obligately aerobic ciliate protozoon, Tetrahymena pyriformis strain ST, are unusual in that they possess a cytochrome oxidase system that does not react with reduced mammalian cytochrome c; the presence of cytochromes a(603)+a(3) is masked in the alpha-band region of spectra by the broad absorption band of cytochrome a(620). 2. Other haemoproteins present include cytochromes b(560), b(556), c(553) and c(549). 3. The reaction of reduced cytochrome a(3) with CO is reversed by flash photolysis, and in the presence of O(2) the subsequent oxidation of this cytochrome is followed by that of cytochrome a(603). 4. Cytochromes a(620) and b(560) also react with CO and with KCN; the latter cytochrome corresponds with that designated cytochrome o by other workers. 5. The contribution of cytochrome a(603) to difference spectra is revealed by making use of the fact that it does not react with KCN. 6. Cytochrome a(620) is unstable, and its alpha-absorption band is lost from spectra of mitochondria which have been aged or treated with ultrasound, detergents or organic solvents. 7. Possible pathways of electron transport via the several different terminal oxidases in Tetrahymena mitochondria are proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345353"}
{"pmid": "4345351", "title": "The regulation of glyceride synthesis in isolated white-fat cells. The effects of palmitate and lipolytic agents.", "content": "The regulation of glyceride synthesis in isolated white-fat cells. The effects of palmitate and lipolytic agents. 1. 0.5mm-Palmitate stimulated incorporation of [U-(14)C]glucose into glyceride glycerol and fatty acids in normal fat cells in a manner dependent upon the glucose concentration. 2. In the presence of insulin the incorporation of 5mm-glucose into glyceride fatty acids was increased by concentrations of palmitate, adrenaline and 6-N-2'-O-dibutyryladenosine 3':5'-cyclic monophosphate up to 0.5mm, 0.5mum and 0.5mm respectively. Higher concentrations of these agents produced progressive decreases in the rate of glucose incorporation into fatty acids. 3. The effects of palmitate and lipolytic agents upon the measured parameters of glucose utilization were similar, suggesting that the effects of lipolytic agents are mediated through increased concentrations of free fatty acids. 4. In fat cells from 24h-starved rats, maximal stimulation of glucose incorporation into fatty acids was achieved with 0.25mm-palmitate. Higher concentrations of palmitate were inhibitory. In fat cells from 72h-starved rats, palmitate only stimulated glucose incorporation into fatty acids at high concentrations of palmitate (1mm and above). 5. The ability of fat cells to incorporate glucose into glyceride glycerol in the presence of palmitate decreased with increasing periods of starvation. 6. It is suggested that low concentrations of free fatty acids stimulate fatty acid synthesis from glucose by increasing the utilization of ATP and cytoplasmic NADH for esterification of these free fatty acids. When esterification of free fatty acids does not keep pace with their provision, inhibition of fatty acid synthesis occurs. Provision of free fatty acids far in excess of the esterification capacity of the cells leads to uncoupling of oxidative phosphorylation and a secondary stimulation of fatty acid synthesis from glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345351"}
{"pmid": "4345354", "title": "Glycine formation during growth of Pseudomonas AM1 on methanol and succinate.", "content": "Glycine formation during growth of Pseudomonas AM1 on methanol and succinate. 1. The mechanism of regeneration of glycine during the growth of Pseudomonas AM1 on C(1) compounds has been investigated by brief incubation of bacterial suspensions with [2,3-(14)C(2)]succinate and observing the incorporation of radioactivity into various metabolites. 2. With the wild-type organism growing on methanol, radioactivity appeared rapidly in glycine and tricarboxylic acid-cycle intermediates, but there was a relatively slow labelling of serine and phosphorylated compounds. Serine became labelled predominantly in the C-2 position. 3. The proportion of radioactivity incorporated into glycine at earliest times was greatly diminished when succinate-grown cells were used. 4. Radioactivity was also incorporated from [2,3-(14)C(2)]succinate into glycine and serine by methanol-grown mutant 20S, which lacks phosphoserine phosphohydrolase. Both the glycine and serine were labelled mainly in C-2. 5. The formation of predominantly [2-(14)C]serine from [2,3-(14)C(2)]succinate in wild-type Pseudomonas AM1, and of [2-(14)C]serine and [2-(14)C]glycine in the mutant lacking the phosphorylated pathway from succinate to serine, is taken as strong evidence for a mechanism of glycine regeneration involving cleavage of a C(4) skeleton between C-2 and C-3, rather than by a direct combination of two C(1) units derived from the growth substrate. 6. The cleavage mechanism is quantitatively more significant during growth on methanol than on succinate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345354"}
{"pmid": "4345355", "title": "A study of the cell surface of tumour, foetal and lymph-node cells by cell electrophoresis after antibody and enzymic treatment.", "content": "A study of the cell surface of tumour, foetal and lymph-node cells by cell electrophoresis after antibody and enzymic treatment. 1. Rabbit anti-(rat foetal liver) serum, absorbed with adult rat liver cells, decreased the electrophoretic mobility of foetal liver cells by 51% and rat hepatoma cells by 45%, indicating the presence of a foetal-type antigen on the hepatoma cell membrane. 2. The chemical nature of the surface antigen was investigated. Incubation with neuraminidase had no effect on adult liver cells but decreased the electrophoretic mobility of foetal liver cells by 51% and of hepatoma cells by 34%; the effect of antiserum was decreased to one-fifth. 3. Sialic acid, or the supernatant from neuraminidase-treated cells, partially blocked the decrease in electrophoretic mobility induced by antiserum. 4. The pH-electrophoretic mobility curves of hepatoma cells treated with antisera were consistent with a sialic acidcontaining antigen on the surface of the tumour cells. 5. Treatment with ribonuclease did not decrease the electrophoretic mobility of adult-liver cells, but decreased that of the foetal liver cells by 17% and hepatoma cells by 29%. 6. In parallel studies made with mouse BP8 ascites-tumour cells ribonuclease decreased the electrophoretic mobility by 39%, that of normal mouse lymph-node cells by 4.8% and allergized mouse lymph-node cells by 13.3%. 7. Trypsin treatment also decreased the electrophoretic mobility of hepatoma cells by 22%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345355"}
{"pmid": "4345356", "title": "Evaluation of the rate-limiting steps in the pathway of glucose metabolism in kidney cortex of normal, diabetic, cortisone-treated and growth hormone-treated rats.", "content": "Evaluation of the rate-limiting steps in the pathway of glucose metabolism in kidney cortex of normal, diabetic, cortisone-treated and growth hormone-treated rats. 1. The activities of gluconeogenic and glycolytic enzymes and the concentrations of citrate, ammonia, amino acids, glycogen, glucose 6-phosphate, acetyl-CoA, lactate and pyruvate were measured in kidney cortex of normal, diabetic, cortisone-treated and growth hormone-treated rats. 2. In kidney cortex of diabetic, cortisone-treated and growth hormone-treated rats the activities of glucose 6-phosphatase (EC 3.1.3.9), fructose 1,6-diphosphatase (EC 3.1.3.11) and phosphopyruvate carboxylase (EC 4.1.1.32) were increased. 3. The activities of glutamate dehydrogenase (EC 1.4.1.3), alanine aminotransferase (EC 2.6.1.2), aspartate aminotransferase (EC 2.6.1.10) and pyruvate carboxylase (EC 6.4.1.1) were increased in diabetic and cortisone-treated rats. In growth hormone-treated rats the activity of aspartate aminotransferase was depressed but those of the other three enzymes were unchanged. 4. The activity of hexokinase (EC 2.7.1.1) was not altered in any of these conditions. Phosphofructokinase (EC 2.7.1.11) activity was depressed only in growth hormone-treated rats. Pyruvate kinase (EC 2.7.1.40) activity was depressed in cortisone-treated and growth hormone-treated rats but unchanged in diabetic rats. 5. Amino acids, acetyl-CoA and glucose 6-phosphate contents were increased in rat kidneys in all these three conditions. Ammonia content was increased in diabetic and cortisone-treated rats but was markedly diminished in growth hormone-treated rats. 6. The [lactate]/[pyruvate] ratio was elevated in diabetic and cortisone-treated rats but unchanged in growth hormone-treated rats. Citrate content was increased in the kidney cortex of diabetic and growth hormone-treated rats but was unchanged in cortisone-treated rats. The activity of ATP citrate lyase (EC 4.1.3.8) was depressed in diabetic and growth hormone-treated rats but was increased in cortisone-treated rats. 7. Glycogen content was moderately elevated in growth hormone-treated rats and markedly elevated in diabetic rats, whereas no change in glycogen content was observed in cortisone-treated rats. Glycogen synthetase (EC 2.4.1.11) activity was unchanged in all these three conditions. Phosphorylase (EC 2.4.1.1) activity was not affected in cortisone-treated rats but was depressed in diabetic and growth hormone-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345356"}
{"pmid": "4345358", "title": "Inducible phosphoenolpyruvate-dependent hexose phosphotransferase activities in Escherichia coli.", "content": "Inducible phosphoenolpyruvate-dependent hexose phosphotransferase activities in Escherichia coli. 1. A method is described for measuring the rate of phosphoenolpyruvate-dependent phosphotransferase activity for a variety of hexoses in toluene-treated suspensions of Escherichia coli. 2. The specific activities of the phosphotransferases that catalyse the phosphorylation of hexoses are greatly affected by the carbon source for growth. 3. In all strains of E. coli tested, fructose phosphotransferase activity is induced by growth on fructose. 4. Strains of E. coli differ greatly in the rate at which they phosphorylate glucose, but all strains possess at least a low glucose phosphotransferase activity under any tested condition of growth. Glucose phosphotransferase activity is further induced by growth on glucose; this does not occur in a mutant that lacks the ability to take up methyl alpha-d-[(14)C]glucopyranoside and hence grows poorly on glucose. 5. When growing on fructose, two strains of E. coli synthesize the inducible glucose phosphotransferase system gratuitously, and to specific activities higher than observed during growth on glucose. A phosphotransferase catalysing the phosphorylation of mannose is similarly induced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345358"}
{"pmid": "4345357", "title": "Effects of starvation on intermediary metabolism in the lactating cow. A comparison with metabolic changes occurring during bovine ketosis.", "content": "Effects of starvation on intermediary metabolism in the lactating cow. A comparison with metabolic changes occurring during bovine ketosis. 1. The purpose of this study was to determine the nature of the metabolic changes associated with carbohydrate and fat metabolism that occurred in the blood and liver of lactating dairy cows during starvation for 6 days. 2. During starvation, the blood concentrations of the free fatty acids and ketone bodies increased, whereas that of citrate decreased. After an initial increase, the blood concentration of glucose subsequently declined as starvation progressed. Starvation caused a significant decrease in the plasma concentration of serine and a significant increase in that of leucine. 3. After 6 days of starvation the hepatic concentrations of oxaloacetate, citrate, phosphoenolpyruvate, 2-phosphoglycerate, 3-phosphoglycerate, glucose, glycogen, ATP and NAD(+) had all decreased, as had the hepatic activities of phosphopyruvate carboxylase (EC 4.1.1.32) and pyruvate kinase (EC 2.7.1.40). 4. The above metabolic changes are similar to those previously found to occur in cows suffering from spontaneous ketosis (Baird et al., 1968; Baird & Heitzman, 1971). 5. Milk yield decreased progressively during starvation. 6. There were marked differences in the ability of individual animals to resist the onset of severe starvation ketosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345357"}
{"pmid": "4345371", "title": "The value of hydroxyurea in assessing repair synthesis of DNA in HeLa cells.", "content": "The value of hydroxyurea in assessing repair synthesis of DNA in HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345371"}
{"pmid": "4345376", "title": "Osteopathic manipulation for syndromes of the brachial plexus.", "content": "Osteopathic manipulation for syndromes of the brachial plexus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345376"}
{"pmid": "4345377", "title": "Alterations of blood sugar and plasma insulin after cryosurgery of functioning islet-cell tumor.", "content": "Alterations of blood sugar and plasma insulin after cryosurgery of functioning islet-cell tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345377"}
{"pmid": "4345380", "title": "Isolation and characterization of temperature-sensitive mutants in a Chinese hamster cell line.", "content": "Isolation and characterization of temperature-sensitive mutants in a Chinese hamster cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345380"}
{"pmid": "4345382", "title": "Clinical and cytologic responses of postmenopausal women to estrogen.", "content": "Clinical and cytologic responses of postmenopausal women to estrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345382"}
{"pmid": "4345384", "title": "Central cholinergic mechanisms in the thermoregulation of the rat.", "content": "Central cholinergic mechanisms in the thermoregulation of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345384"}
{"pmid": "4345383", "title": "Long-distance, \"sensory-bombardment\" ESP in dreams: a failure to replicate.", "content": "Long-distance, \"sensory-bombardment\" ESP in dreams: a failure to replicate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345383"}
{"pmid": "4345387", "title": "Pulmonary contribution to angiotensin I conversion in children.", "content": "Pulmonary contribution to angiotensin I conversion in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345387"}
{"pmid": "4345388", "title": "Some ideas of a neurosurgeon about the necessity of organising the rehabilitation work.", "content": "Some ideas of a neurosurgeon about the necessity of organising the rehabilitation work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345388"}
{"pmid": "4345389", "title": "A new method for quantitative evaluation of bladder sensibility.", "content": "A new method for quantitative evaluation of bladder sensibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345389"}
{"pmid": "4345390", "title": "Review of the present state of assessment and treatment of reno-vascular hypertension.", "content": "Review of the present state of assessment and treatment of reno-vascular hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345390"}
{"pmid": "4345391", "title": "Are some of the connective tissue diseases due to infectious agents?", "content": "Are some of the connective tissue diseases due to infectious agents?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345391"}
{"pmid": "4345392", "title": "The management of abdominal malignancy in children.", "content": "The management of abdominal malignancy in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345392"}
{"pmid": "4345395", "title": "A micrometabolic inhibition test for the estimation of poliovirus neutralizing antibodies.", "content": "A micrometabolic inhibition test for the estimation of poliovirus neutralizing antibodies. A modified micrometabolic inhibition test for the titration of poliovirus neutralizing antibodies is described. The effects of varying both the duration and the temperature of incubation of the serum-virus mixtures were examined. Overnight incubation resulted in a 2-3-fold increase in the titre of the hyperimmune sera tested. The method is simple and economical and appears to be suitable for antibody surveys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345395"}
{"pmid": "4345385", "title": "Paradoxic temperature sensations and the problem of modality-specificity of nerve fibres in the anterolateral tract of the spinal cord.", "content": "Paradoxic temperature sensations and the problem of modality-specificity of nerve fibres in the anterolateral tract of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345385"}
{"pmid": "4345399", "title": "Cyclic 3',5'-nucleotide monophosphate phosphodiesterase activity in hepatomas of different growth rates.", "content": "Cyclic 3',5'-nucleotide monophosphate phosphodiesterase activity in hepatomas of different growth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345399"}
{"pmid": "4345400", "title": "Quantitative aspects of transplacental tumor induction with ethylnitrosourea in rats.", "content": "Quantitative aspects of transplacental tumor induction with ethylnitrosourea in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345400"}
{"pmid": "4345401", "title": "Ultramorphological and ultracytochemical studies on tubuloreticular structures in lymphoid cells.", "content": "Ultramorphological and ultracytochemical studies on tubuloreticular structures in lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345401"}
{"pmid": "4345402", "title": "Electrophoretic analysis of microsomal smooth membrane proteins in rat liver and in Morris hepatoma 5123C.", "content": "Electrophoretic analysis of microsomal smooth membrane proteins in rat liver and in Morris hepatoma 5123C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345402"}
{"pmid": "4345403", "title": "Ultrastructural study of liver invasion by Novikoff hepatoma.", "content": "Ultrastructural study of liver invasion by Novikoff hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345403"}
{"pmid": "4345404", "title": "Urethan and x-ray effects on mice of a tumor-resistant strain, X-Gf.", "content": "Urethan and x-ray effects on mice of a tumor-resistant strain, X-Gf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345404"}
{"pmid": "4345405", "title": "Electron microscopic study of neoplasms induced by urethan and x-rays in X-Gf mice.", "content": "Electron microscopic study of neoplasms induced by urethan and x-rays in X-Gf mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345405"}
{"pmid": "4345407", "title": "Ultrastructural characterization of hamster cells transformed following exposure to ultraviolet-irradiated herpes simplex virus type 2.", "content": "Ultrastructural characterization of hamster cells transformed following exposure to ultraviolet-irradiated herpes simplex virus type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345407"}
{"pmid": "4345408", "title": "Morphological studies of angiosarcomas induced by 1,2-dimethylhydrazine dihydrochloride in Syrian golden hamsters.", "content": "Morphological studies of angiosarcomas induced by 1,2-dimethylhydrazine dihydrochloride in Syrian golden hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345408"}
{"pmid": "4345406", "title": "Regulation of the Embden-Meyerhof pathway in a transplantable rat thyroid tumor.", "content": "Regulation of the Embden-Meyerhof pathway in a transplantable rat thyroid tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345406"}
{"pmid": "4345409", "title": "Elevation of peptidylproline hydroxylase activity and collagen synthesis in spontaneous primary mammary cancers of inbred mice.", "content": "Elevation of peptidylproline hydroxylase activity and collagen synthesis in spontaneous primary mammary cancers of inbred mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345409"}
{"pmid": "4345410", "title": "Workshop in human tumor immunology.", "content": "Workshop in human tumor immunology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345410"}
{"pmid": "4345411", "title": "Intestinal alkaline phoshatase and phytase of chicks: separation of isoenzymes, zinc contents and in vitro effects of zinc.", "content": "Intestinal alkaline phoshatase and phytase of chicks: separation of isoenzymes, zinc contents and in vitro effects of zinc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345411"}
{"pmid": "4345412", "title": "Subcellular localization of thyroglobulin taken up by pig thyroid slices.", "content": "Subcellular localization of thyroglobulin taken up by pig thyroid slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345412"}
{"pmid": "4345413", "title": "A 6-hour bioassay for pituitary gonadotrophins based on radioactive phosphorus uptake by chick testes.", "content": "A 6-hour bioassay for pituitary gonadotrophins based on radioactive phosphorus uptake by chick testes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345413"}
{"pmid": "4345414", "title": "Hormonal regulation of uridine diphosphatase during spermatogenesis in the rat.", "content": "Hormonal regulation of uridine diphosphatase during spermatogenesis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345414"}
{"pmid": "4345415", "title": "Alterations in lipolysis, adenylate cyclase and adenosine 3', 5'-monophosphate levels in isolated fat cells following adrenalectomy.", "content": "Alterations in lipolysis, adenylate cyclase and adenosine 3', 5'-monophosphate levels in isolated fat cells following adrenalectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345415"}
{"pmid": "4345416", "title": "Phosphatidic acid as a precursor of phosphoinositide in the thyroid.", "content": "Phosphatidic acid as a precursor of phosphoinositide in the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345416"}
{"pmid": "4345417", "title": "In vivo effect of GH, ACTH, TSH on thymic anaerobic glycolysis.", "content": "In vivo effect of GH, ACTH, TSH on thymic anaerobic glycolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345417"}
{"pmid": "4345418", "title": "Changing patterns of circulating corticosteroids in rabbits following prolonged treatment with ACTH.", "content": "Changing patterns of circulating corticosteroids in rabbits following prolonged treatment with ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345418"}
{"pmid": "4345419", "title": "Role of bristle-coated membrane in the uptake of ferritin by rat macrophages.", "content": "Role of bristle-coated membrane in the uptake of ferritin by rat macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345419"}
{"pmid": "4345420", "title": "Bovine luteal cells in tissue culture.", "content": "Bovine luteal cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345420"}
{"pmid": "4345421", "title": "Modified distribution of some cyclic AMP phosphodiesterase activities following growth of L cell fibroblasts in presence of prostaglandin E 1 .", "content": "Modified distribution of some cyclic AMP phosphodiesterase activities following growth of L cell fibroblasts in presence of prostaglandin E 1 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345421"}
{"pmid": "4345422", "title": "Alterations of mouse embryo cells during in vitro aging.", "content": "Alterations of mouse embryo cells during in vitro aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345422"}
{"pmid": "4345423", "title": "Effect of chloramphenicol on mitochondrial and extramitochondrial systems in the isolated perfused rat heart.", "content": "Effect of chloramphenicol on mitochondrial and extramitochondrial systems in the isolated perfused rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345423"}
{"pmid": "4345425", "title": "The influence of cell hybridization between B77 virus producing RBI rat cells and L cells on B77 virus and avian Gs antigen production.", "content": "The influence of cell hybridization between B77 virus producing RBI rat cells and L cells on B77 virus and avian Gs antigen production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345425"}
{"pmid": "4345426", "title": "Tumour cell surface specialization in the uptake of nutrients evidenced by cinemicrography as a phenotypic condition for density independent growth.", "content": "Tumour cell surface specialization in the uptake of nutrients evidenced by cinemicrography as a phenotypic condition for density independent growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345426"}
{"pmid": "4345424", "title": "Nucleo-cytoplasmic protein migration during the activation of chick erythrocyte nuclei in heterokaryons.", "content": "Nucleo-cytoplasmic protein migration during the activation of chick erythrocyte nuclei in heterokaryons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345424"}
{"pmid": "4345427", "title": "Thymus and other lymphoid structures in chickens with Rous sarcoma.", "content": "Thymus and other lymphoid structures in chickens with Rous sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345427"}
{"pmid": "4345429", "title": "The redox reactions in propionic acid fermentation. II. Purification of NAD-independent glycerolphosphate dehydrogenase bound to minute particles from supernatant fraction of Propionibacterium arabinosumm.", "content": "The redox reactions in propionic acid fermentation. II. Purification of NAD-independent glycerolphosphate dehydrogenase bound to minute particles from supernatant fraction of Propionibacterium arabinosumm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345429"}
{"pmid": "4345428", "title": "AMP nucleosidase from Azotobacter vinelandii. 3. Kinetics of allosteric interactions.", "content": "AMP nucleosidase from Azotobacter vinelandii. 3. Kinetics of allosteric interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345428"}
{"pmid": "4345430", "title": "Guanosine triphosphate-dependent enzymatic binding of amino-acyl-transfer ribonucleic acid to silk gland ribosomes.", "content": "Guanosine triphosphate-dependent enzymatic binding of amino-acyl-transfer ribonucleic acid to silk gland ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345430"}
{"pmid": "4345431", "title": "Studies on a nuclear petite.", "content": "Studies on a nuclear petite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345431"}
{"pmid": "4345432", "title": "An NAD-linked  -glycerophosphate dehydrogenase in rat liver mitochondria and its response to thyroid hormone.", "content": "An NAD-linked  -glycerophosphate dehydrogenase in rat liver mitochondria and its response to thyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345432"}
{"pmid": "4345433", "title": "Isolation and analysis of glycopeptides from microsomes of an ascites hepatoma, AH 66.", "content": "Isolation and analysis of glycopeptides from microsomes of an ascites hepatoma, AH 66.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345433"}
{"pmid": "4345435", "title": "Ligand size-dependent conformational difference in spin-labeled hemoglobin-nitrosobenzene derivatives.", "content": "Ligand size-dependent conformational difference in spin-labeled hemoglobin-nitrosobenzene derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345435"}
{"pmid": "4345434", "title": "Multimolecular forms of pyruvate kinase. II. Purification of M 2 -type pyruvate kinase from Yoshida ascites hepatoma 130 cells and comparative studies on the enzymological and immunological properties of the three types of pyruvate kinases, L, M 1 , and M 2 .", "content": "Multimolecular forms of pyruvate kinase. II. Purification of M 2 -type pyruvate kinase from Yoshida ascites hepatoma 130 cells and comparative studies on the enzymological and immunological properties of the three types of pyruvate kinases, L, M 1 , and M 2 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345434"}
{"pmid": "4345436", "title": "Studies on polypeptide elongation factor from E. coli. I. Crystalline factor G.", "content": "Studies on polypeptide elongation factor from E. coli. I. Crystalline factor G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345436"}
{"pmid": "4345437", "title": "Interactions between NADH-cytochrome b5 reductase and cytochrome b5 preparations purified from liver microsomes.", "content": "Interactions between NADH-cytochrome b5 reductase and cytochrome b5 preparations purified from liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345437"}
{"pmid": "4345438", "title": "Mode of operation of ampullae of Lorenzini of the skate, Raja.", "content": "Mode of operation of ampullae of Lorenzini of the skate, Raja. Ampullae of Lorenzini are sensitive electroreceptors. Applied potentials affect receptor cells which transmit synaptically to afferent fibers. Cathodal stimuli in the ampullary lumen sometimes evoke all-or-none \"receptor spikes,\" which are negative-going recorded in the lumen, but more frequently they evoke graded damped oscillations. Cathodal stimuli evoke nerve discharge, usually at stimulus strengths subthreshold for obvious receptor oscillations or spikes. Anodal stimuli decrease any ongoing spontaneous nerve activity. Cathodal stimuli evoke long-lasting depolarizations (generator or postsynaptic potentials) in afferent fibers. Superimposed antidromic spikes are reduced in amplitude, suggesting that the postsynaptic potentials are generated similarly to other excitatory postsynaptic potentials. Anodal stimuli evoke hyperpolarizations of nerves in preparations with tonic activity and in occasional silent preparations; presumably tonic release of excitatory transmitter is decreased. These data are explicable as follows: lumenal faces of receptor cells are tonically (but asynchronously) active generating depolarizing responses. Cathodal stimuli increase this activity, thereby leading to increased depolarization of and increased release of transmitter from serosal faces, which are inexcitable. Anodal stimuli act oppositely. Receptor spikes result from synchronized receptor cell activity. Since cathodal stimuli act directly to hyperpolarize serosal faces, strong cathodal stimuli overcome depolarizing effects of lumenal face activity and are inhibitory. Conversely, strong anodal stimuli depolarize serosal faces, thereby causing release of transmitter, and are excitatory. These properties explain several anomalous features of responses of ampullae of Lorenzini.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345438"}
{"pmid": "4345439", "title": "Cyclic adenosine monophosphate in the nervous system of Aplysia californica. I. Increased synthesis in response to synaptic stimulation.", "content": "Cyclic adenosine monophosphate in the nervous system of Aplysia californica. I. Increased synthesis in response to synaptic stimulation. In the isolated abdominal ganglion of Aplysia, previously incubated in adenine-(3)H, the amount of (3)H-labeled adenosine-3',5' monophosphate (cAMP) doubled after electrical stimulation of nerves at a physiological rate (1/sec). No change was detected after 4 min of stimulation. An increase in cAMP was first seen after 15 min; lengthening the period of stimulation to 1 hr did not increase the extent of the effect. ATP contained 50% of the total radioactivity taken up from adenine-(3)H, cAMP about 0.1%. During stimulation both the total amount and the specific radioactivity of adenosine triphosphate (ATP) did not change. Thus, the increased amount of radioactivity found in cAMP after stimulation represented an increase in its rate of synthesis. During stimulation formation of cAMP-(3)H was not altered in nerves or in the cell body of an identified neuron (R2). In addition, no changes were detected in the total amounts of cAMP in the ganglion and in the cell body of R2. It seems likely that the increase was initiated by synaptic activity rather than by action potentials. It was blocked by elevating the concentration of Mg, which also blocks synaptic activity without impairing conduction of impulses. Moreover, impulse activity induced by ouabain and glutamate did not result in increased formation of cAMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345439"}
{"pmid": "4345440", "title": "Cyclic adenosine monophosphate in the nervous system of Aplysia californica. II. Effect of serotonin and dopamine.", "content": "Cyclic adenosine monophosphate in the nervous system of Aplysia californica. II. Effect of serotonin and dopamine. Serotonin and dopamine, both likely transmitter substances in Aplysia, stimulated formation of adenosine-3',5' monophosphate (cAMP) in ganglia, connectives, and identified nerve cell bodies. This widespread distribution suggests that receptors for the response are localized throughout the nervous system, as is adenyl cyclase. Both synthesis of cAMP-(3)H from precursor previously labeled in incubations with adenine-(3)H and total content of cAMP were stimulated up to 15-fold. The acetylcholine analogue carbachol, glutamate, norepinephrine, and histamine were inactive. Full stimulation occurred within 2-4 min of applying serotonin; the extent of the effect was half maximal at 6micro serotonin. Even in the continued presence of serotonin, the increased cAMP diminished with time. When serotonin was removed, tissue remained refractory for 15-20 min; sensitivity returned after 25 min. Serotonin stimulated cAMP after removal of extracellular Na, K, or Cl and in isotonic sucrose, with all extracellular ions removed. Elevating Mg, which blocked the stimulation of cAMP caused by synaptic activity, did not affect the response to serotonin. Thus the response appeared to be independent of transmitter release and of changes in synaptic potentials and current flow. The role of cAMP in neuronal functioning remains to be determined. Conditions which markedly increased cAMP in neurons, however, did not affect the rate of RNA synthesis, nor did they alter the distribution of phosphorylated adenine or uridine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345440"}
{"pmid": "4345445", "title": "Arthritis in viral hepatitis. Report of two cases and review of the literature.", "content": "Arthritis in viral hepatitis. Report of two cases and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345445"}
{"pmid": "4345443", "title": "On the site of action of reserpine on ACTH secretion.", "content": "On the site of action of reserpine on ACTH secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345443"}
{"pmid": "4345447", "title": "Oat-cell carcinoma and severe hypouricemia.", "content": "Oat-cell carcinoma and severe hypouricemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345447"}
{"pmid": "4345449", "title": "Angiotensin I assays.", "content": "Angiotensin I assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345449"}
{"pmid": "4345441", "title": "Variation of alcohol dehydrogenase levels in Drosophila species hybrids.", "content": "Variation of alcohol dehydrogenase levels in Drosophila species hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345441"}
{"pmid": "4345450", "title": "Calcium hypochlorite for disinfection of hydrotherapy equipment.", "content": "Calcium hypochlorite for disinfection of hydrotherapy equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345450"}
{"pmid": "4345453", "title": "Sympathetic ganglia in culture. II. Accessory cells.", "content": "Sympathetic ganglia in culture. II. Accessory cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345453"}
{"pmid": "4345454", "title": "Fibroblasts as a part of the contractile system in duodenal villi of rat.", "content": "Fibroblasts as a part of the contractile system in duodenal villi of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345454"}
{"pmid": "4345458", "title": "Studies on biosynthesis of polymyxin E (colistin). I. Isolation and characteristics of mucoidless R-mutants of Bacillus polymyxa K-1.", "content": "Studies on biosynthesis of polymyxin E (colistin). I. Isolation and characteristics of mucoidless R-mutants of Bacillus polymyxa K-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345458"}
{"pmid": "4345460", "title": "The inner ear in experimental diabetes mellitus.", "content": "The inner ear in experimental diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345460"}
{"pmid": "4345459", "title": "Analysis of taxonomic characteristics of highly active viomycin-producing mutants of Streptomyces griseus var. purpureus.", "content": "Analysis of taxonomic characteristics of highly active viomycin-producing mutants of Streptomyces griseus var. purpureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345459"}
{"pmid": "4345461", "title": "Electron microscopic study of the Auer body.", "content": "Electron microscopic study of the Auer body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345461"}
{"pmid": "4345457", "title": "The effect of bronchoscopic anesthesia upon the yield, accuracy, and cell typing ability of bronchial washing cytology.", "content": "The effect of bronchoscopic anesthesia upon the yield, accuracy, and cell typing ability of bronchial washing cytology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345457"}
{"pmid": "4345462", "title": "Carcinoid tumors--review of literature with special references to sites of origin and humoral substances produced.", "content": "Carcinoid tumors--review of literature with special references to sites of origin and humoral substances produced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345462"}
{"pmid": "4345463", "title": "Primary mixed carcinomas of the bronchus.", "content": "Primary mixed carcinomas of the bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345463"}
{"pmid": "4345464", "title": "Dumping of patients: funding and statistics a problem.", "content": "Dumping of patients: funding and statistics a problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345464"}
{"pmid": "4345465", "title": "Amphetamine psychosis: a \"model\" schizophrenia mediated by catecholamines.", "content": "Amphetamine psychosis: a \"model\" schizophrenia mediated by catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345465"}
{"pmid": "4345466", "title": "Cerebrospinal fluid amine metabolites in affective illness: the probenecid technique.", "content": "Cerebrospinal fluid amine metabolites in affective illness: the probenecid technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345466"}
{"pmid": "4345467", "title": "Dorsal column stimulator implant.", "content": "Dorsal column stimulator implant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345467"}
{"pmid": "4345473", "title": "Management of insomnia.", "content": "Management of insomnia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345473"}
{"pmid": "4345475", "title": "Some recent developments in the physiology of the thyroid gland.", "content": "Some recent developments in the physiology of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345475"}
{"pmid": "4345476", "title": "Progress in neurobiology and its implications for society.", "content": "Progress in neurobiology and its implications for society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345476"}
{"pmid": "4345477", "title": "Modifications of human spermatozoa glycolysis by cyclic adenosine monophosphate (cAMP), estrogens, and follicular fluid.", "content": "Modifications of human spermatozoa glycolysis by cyclic adenosine monophosphate (cAMP), estrogens, and follicular fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345477"}
{"pmid": "4345478", "title": "Tissue distribution of labelled material in vitamin C-deficient guinea pigs after intravenous injection of 1- 14 C) ascorbic acid or (1- 14 C) dehydroascorbic acid.", "content": "Tissue distribution of labelled material in vitamin C-deficient guinea pigs after intravenous injection of 1- 14 C) ascorbic acid or (1- 14 C) dehydroascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345478"}
{"pmid": "4345480", "title": "The forgotten patient.", "content": "The forgotten patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345480"}
{"pmid": "4345488", "title": "Transient inhibition of polyoma virus synthesis by Sendai virus (parainfluenza I). I. Demonstration and nature of the inhibition by inactivated virus.", "content": "Transient inhibition of polyoma virus synthesis by Sendai virus (parainfluenza I). I. Demonstration and nature of the inhibition by inactivated virus. Superinfection of polyoma virus-infected mouse embryo cells by beta-propiolactone-inactivated Sendai virus resulted in a 90% inhibition of the synthesis of infectious polyoma progeny. The interference is dependent upon the time of superinfection and the concentration of the inactivated virus. The inhibition of polyoma virus synthesis is transient in nature since normal synthesis of polyoma progeny virus is seen upon prolonged incubation. Interferon does not appear to be implicated in the interference. Various aspects of the biological and synthetic capabilities of beta-propiolactone-inactivated Sendai virus are also described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345488"}
{"pmid": "4345481", "title": "Psychiatric aides in transition.", "content": "Psychiatric aides in transition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345481"}
{"pmid": "4345479", "title": "A quantitative follow up-study of nursing student reactions to an interactional group experience.", "content": "A quantitative follow up-study of nursing student reactions to an interactional group experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345479"}
{"pmid": "4345490", "title": "Transcription and transport of virus-specific ribonucleic acids in African green monkey kidney cells abortively infected with type 2 adenovirus.", "content": "Transcription and transport of virus-specific ribonucleic acids in African green monkey kidney cells abortively infected with type 2 adenovirus. The techniques of deoxyribonucleic acid-ribonucleic acid (DNA-RNA) hybridization and immunological precipitation were used to compare the synthesis of adenovirus-specific macromolecules in African green monkey kidney (AGMK) cells infected with adenovirus, an abortive infection, and coinfected with both adenovirus and simian virus 40 (SV40), which renders the cells permissive for adenovirus replication. When viral protein synthesis was proceeding at its maximum rate, the incorporation of (14)C-amino acids into adenovirus structural proteins was about 90 times greater in the doubly infected cells than in cells infected only with adenovirus. However, the rates of synthesis of virus-specific ribonucleic acid appeared to be comparable in the two infections at all times measured. A time-dependent increase in the rate of RNA synthesis observed late in the abortive infection was dependent upon the prior replication of viral DNA. Moreover, all virus-specific RNA species that are normally made late in a productive adenovirus infection (i.e., the true late and class II early RNA species) were also detected in the abortive infection. Adenovirus-specific RNA was detected by molecular hybridization in both the cytoplasm and nuclei of abortively infected cells. Comparable amounts of viral RNA were found in the cytoplasmic fractions of AGMK cells infected either with adenovirus or with both adenovirus and SV40. The results of hybridization-inhibition experiments clearly showed that there was a class of virus-specific RNA molecules, representing about 30% of the total, in the nucleus that was not transported to the cytoplasm. This class of RNA was also identified in similar amounts in productively infected human KB cells. The difference in the abilities of cytoplasmic and nuclear RNA to inhibit the hybridization of virus-specific RNA from whole cells was shown not to be due to a difference in the molecular size of the RNA species from the two cell fractions or to the specific loss of a cytoplasmic species during RNA extraction procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345490"}
{"pmid": "4345489", "title": "Transient inhibition of polyoma virus synthesis by sendai virus (parainfluenza I). II. Mechanism of the interference by inactivated virus.", "content": "Transient inhibition of polyoma virus synthesis by sendai virus (parainfluenza I). II. Mechanism of the interference by inactivated virus. The mechanism of the transient inhibition of polyoma virus synthesis by betapropiolactone-inactivated Sendai virus was studied. Polyoma virus early functions did not appear to be affected, although deoxyribonucleic acid (DNA) and structural protein synthesis were inhibited 60 and 35% respectively. The inhibition of macromolecular synthesis was not sufficient to account for the 90% inhibition of infectious progeny formation. Encapsidation of polyoma DNA into mature virions appears to be completely inhibited after superinfection by beta-propiolactone-inactivated Sendai virus. Ultraviolet irradiation of live or beta-propiolactone-inactivated Sendai virus preparations abolishes the interfering capacity, indicating that a functional Sendai virus ribonucleic acid molecule is the interfering component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345489"}
{"pmid": "4345485", "title": "Increase in benefits for the elderly.", "content": "Increase in benefits for the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345485"}
{"pmid": "4345491", "title": "Adenovirus-associated virus multiplication. IX. Extent of transcription of the viral genome in vivo.", "content": "Adenovirus-associated virus multiplication. IX. Extent of transcription of the viral genome in vivo. Nucleic acid hybridization procedures were used to measure the extent of transcription of adenovirus-associated virus (AAV) deoxyribonucleic acid (DNA) in KB cells in the presence of either adenovirus or herpes simplex virus as the helper. Annealing of AAV ribonucleic acid to AAV DNA was monitored by a hybridization inhibition assay on nitrocellulose filters or by hydroxyapatite chromatography. These experiments confirmed the previous observation that, in the presence of either type of helper virus, only one strand of AAV DNA (the thymidine-rich or \"minus\" strand) is transcribed in vivo. However, it was found that only 70 to 80% of this strand appears to be transcribed in vivo. Furthermore, studies with minus strands employing hydroxyapatite chromatography and nuclease S(1), which specifically degrades single-stranded DNA, indicated that up to 20% of the minus strand is self-complementary. It seems likely that these self-complementary sequences account for the bulk of that portion of the minus strand (20 to 30%) which is not transcribed in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345491"}
{"pmid": "4345492", "title": "Temperature-sensitive mutants of vesicular stomatitis virus: in vitro studies of virion-associated polymerase.", "content": "Temperature-sensitive mutants of vesicular stomatitis virus: in vitro studies of virion-associated polymerase. The temperature dependence of the virion-associated polymerase activity of six temperature-sensitive (ts) mutants of vesicular stomatitis virus (tsW10, 11, 14, 16B, 28, and 29) has been examined in vitro and compared to the heat-resistant parent (HR). The polymerase of five of the mutants (tsW10, 11, 14, 16B, and 28) appears to be significantly more ts than that of HR. Because certain pairs of these five mutants can complement each other's in vitro polymerase activity, it appears that in vitro some components involved in the polymerase of one virion can be utilized by another virion. Examination of 19 revertants of tsW11 and tsW16B which had regained their ability to replicate at 38 C showed that their in vitro polymerase activity had also become less ts. Furthermore, it was found that the pairs of mutants which showed in vitro complementation of polymerase activity at 38 C were those which had shown complementation in yielding infectious progeny in mixedly infected cells. These two observations suggest that the ts behavior of the in vitro polymerase activity of the five mutants is related to their inability to replicate at the nonpermissive temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345492"}
{"pmid": "4345486", "title": "Crisis-intervention concepts: implications for nursing practices.", "content": "Crisis-intervention concepts: implications for nursing practices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345486"}
{"pmid": "4345482", "title": "Sensitivity training in psychiatric nursing: evolution and evaluation of a student group experience.", "content": "Sensitivity training in psychiatric nursing: evolution and evaluation of a student group experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345482"}
{"pmid": "4345493", "title": "Thermosensitive block of the Sabin strain of poliovirus type I.", "content": "Thermosensitive block of the Sabin strain of poliovirus type I. The thermosensitive defect of the Sabin LSc2ab strain of poliovirus type I was studied. Transfer of infected KB cells from 36 to 38.5 C resulted in 30% inhibition of viral RNA replication but in 90% inhibition of formation of virions. Neither 74S procapsids nor 14S particles were detected in the cells transferred to the non-permissive temperature. However, procapsids, once accumulated at 36 C, were normally stable at 38.5 C and could transform into virions at that temperature. Viral proteins synthesized at the nonpermissive temperature were not different from those synthesized at permissive temperature, as judged from their pattern in polyacrylamide gel electrophoresis and from the fact that they normally matured into virions when the infected cells were brought back to permissive temperature, even under conditions of inhibition of protein synthesis. This leads to the conclusion that the defect in the Sabin strain studied lies in the assembly of its viral capsid proteins into capsomeres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345493"}
{"pmid": "4345483", "title": "Drug dependence: some aspects of prevention and control. Report of a WHO European Regional Seminar.", "content": "Drug dependence: some aspects of prevention and control. Report of a WHO European Regional Seminar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345483"}
{"pmid": "4345494", "title": "Mechanism of interferon action: inhibition of viral messenger ribonucleic acid translation in L-cell extracts.", "content": "Mechanism of interferon action: inhibition of viral messenger ribonucleic acid translation in L-cell extracts. Encephalomyocarditis (EMC) virus ribonucleic acid (RNA) stimulated the incorporation of (14)C-amino acids into polypeptides in cell-free systems using preincubated S10 extracts from L cells. Incorporation was linear for over 2 hr. Analysis of the tryptic peptides derived from the polypeptide products formed in response to EMC RNA showed them to be virus specific. The major product, a polypeptide of 140,000 in molecular weight, migrated on sodium dodecyl sulfate-polyacrylamide gels with one of the virus-specific polypeptides present in EMC-infected cells. A minor component of molecular weight about 230,000 may correspond to the product of complete translation of the EMC virus genome. Little or no effect of interferon or vaccinia virus infection was observed in the preincubated, cell-free system. The EMC RNA-stimulated incorporation of (14)C-amino acids into polypeptides was not inhibited in extracts derived from L cells early in virus infection, from interferon-treated cells, or from cells subjected to both treatments. Interferon treatment did appear to have a slight inhibitory effect on chain elongation in this system. However, treatment of cells with highly purified interferon before virus infection caused a decrease of about 80% in the capacity of non-preincubated cell extracts to translate added EMC RNA. This effect did not extend to the translation of polyuridylic acid and could be reversed by preincubation of the extracts at 37 C for 20 min. The inhibition of translation was manifest at interferon concentrations as low as 5IU/ml, and in this respect closely paralleled the inhibition of virus growth. Inactivation of the antiviral activity of the interferon by heating or digestion with trypsin also abolished the effect on cell-free protein synthesis. The EMC-specific polypeptides formed in reduced amounts in extracts of interferon-treated vaccinia-infected cells were smaller than those formed in extracts of untreated, vaccinia-infected cells. Thus, inhibition of initiation or elongation of polypeptides, or both, can be demonstrated in cell-free systems employing non-preincubated extracts from interferon-treated, virus-infected cells. These results indicate that antiviral activity of interferon is directed against the translation of viral messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345494"}
{"pmid": "4345484", "title": "The \"Brand Name\" game.", "content": "The \"Brand Name\" game.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345484"}
{"pmid": "4345487", "title": "Do perceptual changes occur in crisis? A case study.", "content": "Do perceptual changes occur in crisis? A case study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345487"}
{"pmid": "4345497", "title": "Genetic studies on inbreeding in some Japanese populations. VII. The effects of parental consanguinity on skeletal age in Shizuoka children.", "content": "Genetic studies on inbreeding in some Japanese populations. VII. The effects of parental consanguinity on skeletal age in Shizuoka children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345497"}
{"pmid": "4345495", "title": "Classification of rhabdovirus proteins: a proposal.", "content": "Classification of rhabdovirus proteins: a proposal. A simple alphabetical classification is offered as a means to codify the proteins of rhabdoviruses, using vesicular stomatitis virus as the prototype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345495"}
{"pmid": "4345496", "title": "Density heterogeneity of simian virus 40 ribonucleic acid late after infection of permissive cells.", "content": "Density heterogeneity of simian virus 40 ribonucleic acid late after infection of permissive cells. Ribonucleic acid (RNA) was isolated from CV-1 cells 44 hr after simian virus 40 (SV40) infection. The molecules containing SV40 base sequences were characterized with respect to their buoyant density distribution. The density of these molecules was compared to that of single- and double-stranded RNA synthesized by using SV40 DNA and Escherichia coli RNA polymerase. The results suggest that about 20% of the SV40 RNA in the infected cells consisted of partially double-stranded molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345496"}
{"pmid": "4345498", "title": "The role of alpha-toxin of Clostridium perfringens in experimental gas gangrene in guinea pigs.", "content": "The role of alpha-toxin of Clostridium perfringens in experimental gas gangrene in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345498"}
{"pmid": "4345499", "title": "Where we are and where are we going?", "content": "Where we are and where are we going?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345499"}
{"pmid": "4345500", "title": "Organization man: a study in rigor mortis.", "content": "Organization man: a study in rigor mortis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345500"}
{"pmid": "4345501", "title": "Possibility that angiotensin resulting from unilateral kidney disease affects contralateral renal function.", "content": "Possibility that angiotensin resulting from unilateral kidney disease affects contralateral renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345501"}
{"pmid": "4345502", "title": "Control of the synthesis of fatty-acid synthetase in rat liver by insulin, glucagon, and adenosine 3':5' cyclic monophosphate.", "content": "Control of the synthesis of fatty-acid synthetase in rat liver by insulin, glucagon, and adenosine 3':5' cyclic monophosphate. The usual increase in the activity of liver fatty-acid synthetase that occurs on refeeding of a fat-free diet to previously fasted rats is abolished in diabetic animals. Insulin specifically restores this increase by enhancement of the rate of synthesis of fatty-acid synthetase. However, glucagon and cyclic AMP inhibit the increase in the activity of fatty-acid synthetase. Therefore, the concentration of fatty-acid synthetase in rat liver is under the control of the relative concentrations of insulin and glucagon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345502"}
{"pmid": "4345503", "title": "Luteinizing hormone receptors: specific binding of human luteinizing hormone to homogenates of luteinized rat ovaries.", "content": "Luteinizing hormone receptors: specific binding of human luteinizing hormone to homogenates of luteinized rat ovaries. Binding of human [(125)I]luteinizing hormone to homogenates of luteinized rat ovaries is dependent upon time, temperature, and pH and is saturable. Injection of human chorionic gonadotropin in vivo or addition of unlabeled human chorionic gonadotropin or human or ovine luteinizing hormone in vitro inhibits binding, whereas follicle stimulating hormone or prolactin is without effect. The dissociation constant for binding of luteinizing hormone receptor is 0.79 nM. The number of binding sites is 94 femtomol/mg of wet weight. NaCl, KCl, MgSO(4), and CaCl(2) at concentrations below 10 mM have no effect on binding, while all salts significantly inhibit binding at 150 mM. Binding of [(125)I]luteinizing hormone to its receptors is destroyed by proteolytic enzymes and by phospholipase C and D. The total binding activity is quantitatively recovered in the 2000 x g pellet of the homogenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345503"}
{"pmid": "4345504", "title": "Alteration of nucleoside transport of Chinese hamster cells by dibutyryl adenosine 3':5'-cyclic monophosphate.", "content": "Alteration of nucleoside transport of Chinese hamster cells by dibutyryl adenosine 3':5'-cyclic monophosphate. Cultured Chinese hamster ovary cells showed no significant change in generation time or fraction in the S-phase in the presence of 1 mM N(6),O(2')-dibutyryl adenosine 3':5'-cyclic monophosphate. Growth continued for at least two generations after expression of the morphological transformation induced by this cyclic AMP analog. Despite identical growth rates, apparent rates of DNA and RNA synthesis (incorporation of [(3)H]-thymidine or [(3)H]uridine) were reduced up to 15-fold in log phase by 1 mM cyclic nucleotide. [(3)H]Deoxycytidine incorporation was much less sensitive to dibutyryl cyclic AMP. Uptake studies with [(3)H]thymidine demonstrated an inhibition of transport rate dependent on the concentration of dibutyryl cyclic AMP in the growth medium. The rate of thymidine uptake at 1 degrees was decreased 21-fold by 1 mM cyclic nucleotide; half-maximal inhibition occurred at 6 muM. At 37 degrees , the pool size of acid-soluble thymidylate was strongly reduced by 1 mM cyclic nucleotide, and synergistic reduction of the pool size was found with 0.5 mM aminophylline. Phosphorylation of the acid-soluble intracellular label was unaffected by dibutyryl cyclic AMP. Inhibition of thymidine uptake is attributed to an observed decrease in thymidine kinase activity caused by growth in 1 mM dibutyryl cyclic AMP, and possibly to a simultaneous alteration in membrane permeability. Kinase-facilitated uptake of other metabolites may be regulated in a similar fashion by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345504"}
{"pmid": "4345506", "title": "Translation of encephalomyocarditis viral RNA in oocytes of Xenopus laevis.", "content": "Translation of encephalomyocarditis viral RNA in oocytes of Xenopus laevis. RNA from encephalomyocarditis virus was injected into oocytes of Xenopus laevis. After incubation of the oocytes in [(35)S]methionine, polyacrylamide gel electrophoresis showed that a new series of polypeptides had been synthesized. They were identical in size to the polypeptides that appeared in ascites cells after infection with this virus. Electrophoretic and chromatographic analysis of the methionine-containing tryptic peptides from three of the induced polypeptides confirmed that they were virus-specific. All of the bands that appeared in ascites cells after infection also appeared in oocytes after injection of RNA from the virus. We conclude that Xenopus oocytes translate a mammalian viral mRNA faithfully and extensively, and perform normal post-translational modifications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345506"}
{"pmid": "4345505", "title": "Initiation of picornavirus protein synthesis in ascites cell extracts.", "content": "Initiation of picornavirus protein synthesis in ascites cell extracts. The current model of picornavirus protein formation implies that initiation of protein synthesis occurs at a single site on the viral RNA, and that the large polypeptide formed is later cleaved. A direct test of this model was made in vitro by studying the incorporation of [(35)S]methionine from rabbit liver Met-tRNA(M) (Met) and fMet-tRNA(F) (Met) into encephalomyocarditis virus RNA-coded proteins in extracts of Ehrlich ascites cells. The incorporation of N-formylmethionine was complete within 5 min, while utilization of Met-tRNA(M) (Met) continued for 20 min. Tryptic digests of [(35)S]methionine-labeled products from Met-tRNA(M) (Met) analyzed by anion-exchange chromatography yielded more than 30 peptides, as compared to about 15 [(35)S]methionine-labeled peptides from purified encephalomyocarditis virus. In contrast, products labeled with fMet-tRNA(F) (Met) yielded one major (26)S-labeled tryptic peptide. The N-terminal location of methionine in this peptide was verified by Edman degradation. One predominant N-terminal tryptic peptide was also obtained with fMet-tRNA(F) (Met) when mouse Elberfeld and mengo-virus RNAs were used as messengers. On the basis of N-terminal compared with internal labeling of the products, no evidence for in vitro post-translational cleavage was found. The results are consistent with a single initiation site for synthesis of picornavirus proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345505"}
{"pmid": "4345507", "title": "Hormonal interactions in the uterus: inhibition of isoproterenol-induced accumulation of adenosine 3':5'-cyclic monophosphate by oxytocin and prostaglandins.", "content": "Hormonal interactions in the uterus: inhibition of isoproterenol-induced accumulation of adenosine 3':5'-cyclic monophosphate by oxytocin and prostaglandins. Interactions of hormones stimulating and inhibiting uterine contraction were studied in vitro in uteri from oophorectomized rats. The beta-adrenergic effector, isoproterenol, a potent inhibitor of contraction, produced a dose-related increase of adenylate cyclase and accumulation of adenosine 3':5'-cyclic monophosphate (cAMP) that was inhibitable by propranolol. Oxytocin, which stimulates contraction, effectively inhibited accumulation of uterine cAMP induced by isoproterenol in the presence or absence of theophylline. Prostaglandins E(2) and F(2alpha), each at a maximum effective concentration of 0.5 muM, also inhibited accumulation of cAMP induced by isoproterenol, consistent with their effect in stimulation of uterine contraction. Prostaglandin E(2), but not prostaglandin F(2alpha), stimulated cAMP accumulation in a dose-related manner at concentrations in excess of 0.5 muM. Neither propranolol nor oxytocin inhibited that response. Bovine endometrial adenylate cyclase failed to respond to isoproterenol but was stimulated by prostaglandins E(1) and E(2). When myometrial preparations were studied, isoproterenol stimulation and prostaglandin effects were observed as for whole castrate uterus. The competitive physiological actions of beta-adrenergic effectors on the one hand, and oxytocin and prostaglandins on the other hand, are based on their influences on a myometrial adenylate cyclase. Stimulation of uterine cAMP accumulation by prostaglandin E(2) is due to action at a different and unrelated site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345507"}
{"pmid": "4345508", "title": "A DNA fragment of Herpes simplex 2 and its transcription in human cervical cancer tissue.", "content": "A DNA fragment of Herpes simplex 2 and its transcription in human cervical cancer tissue. A human cervical tumor, free of detectable infectious herpes simplex 2 virus, contained a fragment comprising 39% of herpes viral DNA. Renaturation kinetics indicate that an average of 1 to 3.5 DNA fragments of herpes simplex virus are present per cell, depending on the ploidy of the cells in this particular tumor. Virus-specific sequences were found linked to highly repetitive sequences of host DNA, which reassociated under conditions designed to preclude reassociation of viral sequences. The tumor also contained RNA transcripts complementary to 5% of the viral DNA. The fraction of viral DNA template transcribed in the cervical tumor is considerably less than that transcribed in productively infected cells (50%).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345508"}
{"pmid": "4345510", "title": "Selective inhibition of growth of transformed cells by protease inhibitors.", "content": "Selective inhibition of growth of transformed cells by protease inhibitors. Five protease inhibitors with different modes of action were found to reduce the growth of transformed mouse (Py3T3, SV3T3, and 3T12) and hamster (PyBHK) cells. Some of these inhibitors caused the transformed cells to cease growth at saturation densities characteristic for nontransformed cells. The protease inhibitors were strikingly selective with regard to the transformed cells; they had essentially no effect on the growth of the nontransformed cells. From this result, it is concluded that the inhibitors block a protease-like activity that is required for the unrestrained growth of transformed cells. The inhibitors exerted their effect directly on the cells; they did not affect growth by interacting with serum components of the medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345510"}
{"pmid": "4345511", "title": "Pararticular soft tissue changes in systemic diseases.", "content": "Pararticular soft tissue changes in systemic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345511"}
{"pmid": "4345509", "title": "Isolation and subunit structure of polycytidylate-dependent RNA polymerase of encephalomyocarditis virus.", "content": "Isolation and subunit structure of polycytidylate-dependent RNA polymerase of encephalomyocarditis virus. A polycytidylate-dependent RNA polymerase of encephalomyocarditis virus was isolated from infected BHK 21 cells. The enzyme was associated with a smooth-membrane fraction, from which it was extracted by a mixture of sodium dodecyl sulfate, Triton X-100, and dithiothreitol, and further purified by chromatography on a Dowex-1 column and by glycerol gradient sedimentation. Analysis of a 6S glycerol gradient peak of RNA polymerase activity by sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed the presence of five polypeptides, of molecular weights 72,000, 65,000, 57,000, 45,000, and 35,000. The molecular weights of four of the polypeptides (72,000, 65,000, 45,000, and 35,000) are almost identical to the reported molecular weights of the four subunits of Qbeta replicase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345509"}
{"pmid": "4345512", "title": "Tumors of the soft tissues of the extremities.", "content": "Tumors of the soft tissues of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345512"}
{"pmid": "4345514", "title": "Effects of adrenal cortical hormones on carbohydrate, protein, and fat metabolism.", "content": "Effects of adrenal cortical hormones on carbohydrate, protein, and fat metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345514"}
{"pmid": "4345516", "title": "Evaluation of optic neuropathy with B-scan ultrasonography.", "content": "Evaluation of optic neuropathy with B-scan ultrasonography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345516"}
{"pmid": "4345515", "title": "Phosphoenolpyruvate carboxykinase. II. Hormonal controls.", "content": "Phosphoenolpyruvate carboxykinase. II. Hormonal controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345515"}
{"pmid": "4345518", "title": "Issues raised in a group setting by patients recovering from myocardial infarction.", "content": "Issues raised in a group setting by patients recovering from myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345518"}
{"pmid": "4345517", "title": "A follow-up study of narcotic addicts in the NARA program.", "content": "A follow-up study of narcotic addicts in the NARA program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345517"}
{"pmid": "4345520", "title": "Uptake of Adenovirus by intestinal absorptive cells of the suckling rat. I. The neonatal ileum.", "content": "Uptake of Adenovirus by intestinal absorptive cells of the suckling rat. I. The neonatal ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345520"}
{"pmid": "4345519", "title": "Multivesicular bodies and related structures of the syncytiotrophoblast of human term placenta.", "content": "Multivesicular bodies and related structures of the syncytiotrophoblast of human term placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345519"}
{"pmid": "4345521", "title": "Uptake of adenovirus by intestinal absorptive cells of the suckling rat. II. The neonatal jejunum.", "content": "Uptake of adenovirus by intestinal absorptive cells of the suckling rat. II. The neonatal jejunum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345521"}
{"pmid": "4345522", "title": "Trout hepatoma: fibrosis and lymphocytosis as suppressive mechanisms in the rainbow trout (Salmo gairdneri).", "content": "Trout hepatoma: fibrosis and lymphocytosis as suppressive mechanisms in the rainbow trout (Salmo gairdneri).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345522"}
{"pmid": "4345523", "title": "Neutrophil proteases in inflammation.", "content": "Neutrophil proteases in inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345523"}
{"pmid": "4345524", "title": "Abetalipoproteinemia.", "content": "Abetalipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345524"}
{"pmid": "4345525", "title": "Epstein-Barr virus infection in relation to infectious mononucleosis and Burkitt's lymphoma.", "content": "Epstein-Barr virus infection in relation to infectious mononucleosis and Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345525"}
{"pmid": "4345527", "title": "Structure-melanotropic activity relationship in synthetic polypeptides related to ACTH.", "content": "Structure-melanotropic activity relationship in synthetic polypeptides related to ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345527"}
{"pmid": "4345526", "title": "Transsulfuration in fetal and postnatal mammalian liver and brain. Cystathionine synthase, its relation to hormonal influences, and cystathionine.", "content": "Transsulfuration in fetal and postnatal mammalian liver and brain. Cystathionine synthase, its relation to hormonal influences, and cystathionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345526"}
{"pmid": "4345528", "title": "Some aspects of the relationship between N-terminal structure and MSH activity of three decapeptides related to ACTH: a comparative study of gly 1 -ACTH(1-10)OH, ibu 1 -ACTH(1-10)OH and  -ala 1 -ACTH(1-10)OH.", "content": "Some aspects of the relationship between N-terminal structure and MSH activity of three decapeptides related to ACTH: a comparative study of gly 1 -ACTH(1-10)OH, ibu 1 -ACTH(1-10)OH and  -ala 1 -ACTH(1-10)OH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345528"}
{"pmid": "4345529", "title": "Isolation of prolactin granules from rat anterior pituitary glands.", "content": "Isolation of prolactin granules from rat anterior pituitary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345529"}
{"pmid": "4345530", "title": "Thyrotropin and thyroidal peroxidase activity.", "content": "Thyrotropin and thyroidal peroxidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345530"}
{"pmid": "4345531", "title": "The initiation of fetal adrenocorticotrophic activity in the rat.", "content": "The initiation of fetal adrenocorticotrophic activity in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345531"}
{"pmid": "4345532", "title": "ACTH and MSH production by a single cloned mouse pituitary tumor cell line.", "content": "ACTH and MSH production by a single cloned mouse pituitary tumor cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345532"}
{"pmid": "4345533", "title": "Biological activity of 1,25-dihydroxyvitamin D3 in the rat.", "content": "Biological activity of 1,25-dihydroxyvitamin D3 in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345533"}
{"pmid": "4345534", "title": "A chick bioassay for parathyroid hormone.", "content": "A chick bioassay for parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345534"}
{"pmid": "4345535", "title": "Avian bioassay method for parathyroid hormone.", "content": "Avian bioassay method for parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345535"}
{"pmid": "4345536", "title": "Use of a modified radioligand assay to measure the effect of estradiol on uterine adenosine 3',5'-cyclic monophosphate.", "content": "Use of a modified radioligand assay to measure the effect of estradiol on uterine adenosine 3',5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345536"}
{"pmid": "4345537", "title": "Effects of methylxanthines on adenosine 3',5'-monophosphate and corticosterone in the rat adrenal.", "content": "Effects of methylxanthines on adenosine 3',5'-monophosphate and corticosterone in the rat adrenal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345537"}
{"pmid": "4345538", "title": "Effects of cholera and E. coli enterotoxins on cyclic adenosine 3',5'-monophosphate levels and intermediary metabolism in the thyroid.", "content": "Effects of cholera and E. coli enterotoxins on cyclic adenosine 3',5'-monophosphate levels and intermediary metabolism in the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345538"}
{"pmid": "4345539", "title": "Adenosine 3',5'-cyclic monophosphate and phosphodiesterase activities in isolated fetal and neonatal rat pancreatic islets.", "content": "Adenosine 3',5'-cyclic monophosphate and phosphodiesterase activities in isolated fetal and neonatal rat pancreatic islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345539"}
{"pmid": "4345540", "title": "Effects of subunits of TSH and LH on TSH stimulation of cyclic AMP accumulation in dog thyroid slices.", "content": "Effects of subunits of TSH and LH on TSH stimulation of cyclic AMP accumulation in dog thyroid slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345540"}
{"pmid": "4345541", "title": "Stereoisomerism in adrenergic drugs.", "content": "Stereoisomerism in adrenergic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345541"}
{"pmid": "4345545", "title": "Islet cell tumour in the newborn.", "content": "Islet cell tumour in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345545"}
{"pmid": "4345546", "title": "Autoimmune hemolytic anemia and cytomegalovirus infection in a six-months-old child, treated with azathioprine.", "content": "Autoimmune hemolytic anemia and cytomegalovirus infection in a six-months-old child, treated with azathioprine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345546"}
{"pmid": "4345547", "title": "Studies on invasiveness of polyoma virus transformed BHK cells on chorioallantoic membrane of chick.", "content": "Studies on invasiveness of polyoma virus transformed BHK cells on chorioallantoic membrane of chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345547"}
{"pmid": "4345548", "title": "The role of viruses in the pathogenesis of ocular tumors.", "content": "The role of viruses in the pathogenesis of ocular tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345548"}
{"pmid": "4345549", "title": "Trapping of radicals formed in the photochemical reaction between hydrogen peroxide and some pyrimidine bases, nucleosides, nucleotides, and yeast nucleic acid.", "content": "Trapping of radicals formed in the photochemical reaction between hydrogen peroxide and some pyrimidine bases, nucleosides, nucleotides, and yeast nucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345549"}
{"pmid": "4345550", "title": "Oxidation of heme proteins by alkyl halides.", "content": "Oxidation of heme proteins by alkyl halides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345550"}
{"pmid": "4345551", "title": "Reversible disaggregation of myofilaments in vertebrate smooth muscle.", "content": "Reversible disaggregation of myofilaments in vertebrate smooth muscle. Strips of taenia coli from guinea pigs were incubated under isometric conditions in Krebs-Ringer bicarbonate saline (MKR) containing various concentrations of Ca(+2) and/or Mg(+2). Spontaneous or chemically induced contractile activity was abolished within 15 min of exposure to MKR containing Ca(+2) at concentrations below 10(-6) M; contractile activity was restored by reincubation in normal MKR after 1-2 h. Exposure of taenia coli to MKR containing Ca(+2) at concentrations below 10(-6) M for 1 h or more led to loss of thick and thin myofilaments from the sarcoplasm as observed with the electron microscope. Except for the loss of these two filament types, the cells contained all other structural features observed in preparations incubated in MKR containing Ca(+2) at its normal level (1.3 x 10(-3) M). The loss of thick and thin myofilaments in strips exposed to a Ca(+2) concentration below 10(-6) M was reversed by reincubation for 30 min in MKR containing normal Ca(+2) levels. The observed loss of thick and thin myofilaments in response to low Ca(+2) is interpreted as resulting from the disaggregation of some or all of the molecular components of these two filament types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345551"}
{"pmid": "4345552", "title": "Contact-inhibited revertant cell lines isolated from SV 40-transformed cells. IV. Microfilament distribution and cell shape in untransformed, transformed, and revertant Balb-c 3T3 cells.", "content": "Contact-inhibited revertant cell lines isolated from SV 40-transformed cells. IV. Microfilament distribution and cell shape in untransformed, transformed, and revertant Balb-c 3T3 cells. A COMPARISON IS MADE OF THE ULTRASTRUCTURE OF THE CELL PERIPHERY IN THREE CLONED CELL LINES: untransformed Balb/c 3T3 cells, SV40-transformed Balb/c 3T3 cells, and revertant cells obtained from the transformed cell line by a selection technique utilizing concanavalin A. Both thin-section and surface replication techniques are used for in situ examination of the cell lines. Microfilaments, 70 A in diameter (called alpha filaments), are abundant in untransformed and revertant cell lines, particularly in the anterior expansions of the cells, which tend to have many microvilli and small pseudopodia. Alpha filaments are diminished in the anterior expansions of transformed cells, which contain large blunt pseudopodia and relatively few microvilli. Surface replicas confirm the impression gained from thin sections that transformed cells have a greater proportion of their cell surface involved in bulging pseudopodia than either untransformed or revertant cells. Since alpha filaments are shown to bind heavy meromyosin and are similar to F-actin, these filaments are thought to be important in cell motility. These observations suggest that a close relationship exists between decreased alpha filaments, bulging pseudopodia, and loss of contact inhibition of movement in transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345552"}
{"pmid": "4345553", "title": "Regulation of microtubules in Tetrahymena. I. Electron microscopy of oral replacement.", "content": "Regulation of microtubules in Tetrahymena. I. Electron microscopy of oral replacement. The coupled resorption and redifferentiation of oral structures which occurs in Tetrahymena pyriformis under conditions of amino acid deprivation has been studied by transmission electron microscopy. Two patterns of ciliary resorption have been found, (a) in situ, and (b) after withdrawal into the cytoplasm. No autophagic vacuoles containing cilia or ciliary axonemes have been seen. Stomatogenic field basal bodies arise by a process of rapid sequential nucleation, with new ones always appearing next to more mature ones, even though the latter may not be fully differentiated. Accessory radial ribbons of microtubules develop immediately adjacent to oral field basal bodies as a late step in their maturation. It can be seen that the formation of basal bodies and their orientation within the oral complex are separate processes. This is true for about 130 of the approximately 170 oral basal bodies; the remaining 40 or so form within the patterned groups of ciliary units as a later event. Clusters of randomly oriented thin-walled microtubules are found surrounding oral basal bodies at all times during stomatogenesis. They may either represent stores of microtubule subunit protein, or serve as effectors of basal body movement during their orientation into pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345553"}
{"pmid": "4345554", "title": "Rapid degeneration of ampullary electroreceptor organs after denervation.", "content": "Rapid degeneration of ampullary electroreceptor organs after denervation. Electroreceptors (ampullary organs) of the transparent catfish (Kryptopterus bicirrhus) lie in the epidermis, and contain spherical receptor cells that receive purely afferent innervation from the lateral line nerve. Section of this nerve causes rapid degenerative changes to occur in the receptors. Fine structural alterations occur in the receptor cell synapses and nerve fiber 6-12 h postoperatively. Disruption of the receptor cells begins by 18 h and most are lost by 48 h. By 72 h supporting cells and secretory cells also show marked degeneration, and by 96 h they may be totally lost. The rapid degeneration of the electroreceptor organs of Kryptopterus should make them a useful preparation for analysis of neurotrophic functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345554"}
{"pmid": "4345557", "title": "Chicken cardiac muscle: its elusive extended junctional sarcoplasmic reticulum and sarcoplasmic reticulum fenestrations.", "content": "Chicken cardiac muscle: its elusive extended junctional sarcoplasmic reticulum and sarcoplasmic reticulum fenestrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345557"}
{"pmid": "4345555", "title": "Dibutyryl cyclic adenosine 3'5' monophosphate, sugar transport, and regulatory control of cell division in normal and transformed cells.", "content": "Dibutyryl cyclic adenosine 3'5' monophosphate, sugar transport, and regulatory control of cell division in normal and transformed cells. Swiss 3T3 cells exhibit contact-regulated cell growth and have a lower ability to transport 2-deoxyglucose than polyoma (Py)-transformed 3T3 cells. Py3T3 cells treated with dibutyryl cyclic adenosine 3'5' monophosphate (dBcAMP) and theophylline have reduced cell growth and transport 2-deoxyglucose at the same rate as normal 3T3 cells. Evidence that the cessation of cell growth and reduced transport abilities in Py3T3 cells does not represent a return to contact-regulated growth comes from the following observations. First, treating high density Py3T3 cells with dBcAMP allows more than two doublings of cell number, even though ability to transport 2-deoxyglucose is returned to levels equal to those of normal 3T3 cells. Second, dBcAMP prevents serum-stimulated increases in 2-deoxyglucose transport in Py3T3 but not in 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345555"}
{"pmid": "4345556", "title": "Secretion and endocytosis in insulin-stimulated rat adrenal medulla cells.", "content": "Secretion and endocytosis in insulin-stimulated rat adrenal medulla cells. Insulin was used to deplete the adrenalin stores of rat adrenal medulla cells. Release of secretion was observed to occur by exocytosis. In addition, during the stages of massive release of secretory granules, the insulin-treated preparations showed greatly enhanced endocytic uptake of horseradish peroxidase. The tracer was taken up within vesicles, tubules, multivesicular bodies, and dense bodies. From acid phosphatase studies and from previous work it appears that many of the structures in which peroxidase accumulates are lysosomes or are destined to fuse with lysosomes. Subsequent to the period of intense exocytosis and endocytosis, there is a transient accumulation of lipid droplets in the adrenalin cells. The cells then regranulate, with new granules forming near the Golgi region. These results suggest that under the conditions used, much of the membrane that initially surrounds secretory granules is degraded after release of the granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345556"}
{"pmid": "4345559", "title": "Determination of vitamins D by gas-liquid chromatography. II. Rapid assay for vitamin  D2  in the presence of vitamin A and E.", "content": "Determination of vitamins D by gas-liquid chromatography. II. Rapid assay for vitamin  D2  in the presence of vitamin A and E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345559"}
{"pmid": "4345561", "title": "Observations on the quantitative analysis of fatty acids in bovine blood serum.", "content": "Observations on the quantitative analysis of fatty acids in bovine blood serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345561"}
{"pmid": "4345567", "title": "Liver adaptation and injury in alcoholism.", "content": "Liver adaptation and injury in alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345567"}
{"pmid": "4345566", "title": "Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain.", "content": "Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345566"}
{"pmid": "4345568", "title": "[Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-1973].", "content": "[Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-1973].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345568"}
{"pmid": "4345569", "title": "Therapeutic value of vitamin D metabolites.", "content": "Therapeutic value of vitamin D metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345569"}
{"pmid": "4345571", "title": "Embryonic chick intestine in organ culture: response to vitamin D 3  and its metabolites.", "content": "Embryonic chick intestine in organ culture: response to vitamin D 3  and its metabolites. Embryonic chick intestine maintained in organ culture responded to vitamin D(3) and its metabolites 25-hydroxycholecalciferol and 1,25-dihydroxycholecalciferol by synthesis of calcium-binding protein and enchanced calcium-45 uptake. The dihydroxy metabolite was by far the most potent inducer of the protein and also acted more rapidly than vitamin D(3) to stimulate isotope uptake. Despite its lower potency, vitamin D(3) itself was effective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345571"}
{"pmid": "4345570", "title": "Hypothalamic regulatory hormones.", "content": "Hypothalamic regulatory hormones. The molecular structures of several polypeptides isolated from hypothalamic tissue have been established and the synthesis of these compounds has been achieved. These polypeptides selectively stimulate or inhibit the release of anterior pituitary hormones and melanocyte-stimulating hormone. Various studies indicate their important physiological role and support the concept that some of these polypeptides are hormones. Some synthetic hypothalamic hormones and their derivatives may find important clinical and veterinary applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345570"}
{"pmid": "4345562", "title": "Investigation of the structure of a model iron-sulfur protein by spin and luminescence label methods.", "content": "Investigation of the structure of a model iron-sulfur protein by spin and luminescence label methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345562"}
{"pmid": "4345576", "title": "Bowel control.", "content": "Bowel control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345576"}
{"pmid": "4345565", "title": "Study of the kinetics of formation of ternary complex lactate dehydrogenase-NAD-pyruvate.", "content": "Study of the kinetics of formation of ternary complex lactate dehydrogenase-NAD-pyruvate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345565"}
{"pmid": "4345577", "title": "Suppression of periodic fever with estrogen.", "content": "Suppression of periodic fever with estrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345577"}
{"pmid": "4345563", "title": "The origin of mitochondrial RNA of animal tissues studied by hybridization with mitochondrial DNA.", "content": "The origin of mitochondrial RNA of animal tissues studied by hybridization with mitochondrial DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345563"}
{"pmid": "4345578", "title": "Respiration of homogenates and crude mitochondrial fractions of bovine attached gingiva.", "content": "Respiration of homogenates and crude mitochondrial fractions of bovine attached gingiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345578"}
{"pmid": "4345564", "title": "EPR investigation of various nitroxide free radicals in biological and artificial membranes.", "content": "EPR investigation of various nitroxide free radicals in biological and artificial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345564"}
{"pmid": "4345583", "title": "Composition and structure of the O-specific side chain of endotoxin from Serratia marcescens Bizio.", "content": "Composition and structure of the O-specific side chain of endotoxin from Serratia marcescens Bizio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345583"}
{"pmid": "4345584", "title": "Substrate stereochemical requirements in the reductive inactivation of uridine diphosphate galactose 4-epimerase by sugar and 5'-uridine monophosphate.", "content": "Substrate stereochemical requirements in the reductive inactivation of uridine diphosphate galactose 4-epimerase by sugar and 5'-uridine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345584"}
{"pmid": "4345585", "title": "Effects of photooxidation of histidine-38 on the various catalytic activities of glyceraldehyde-3-phosphate dehydrogenase.", "content": "Effects of photooxidation of histidine-38 on the various catalytic activities of glyceraldehyde-3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345585"}
{"pmid": "4345586", "title": "Effects of photooxidation of histidine-38 on the acetylphosphatase activity of glyceraldehyde-3-phosphate dehydrogenase.", "content": "Effects of photooxidation of histidine-38 on the acetylphosphatase activity of glyceraldehyde-3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345586"}
{"pmid": "4345591", "title": "Comparison of a selective and a non-selective medium in the diagnosis of gonorrhoea to ascertain the sensitivity of Neisseria gonorrhoeae to vancomycin.", "content": "Comparison of a selective and a non-selective medium in the diagnosis of gonorrhoea to ascertain the sensitivity of Neisseria gonorrhoeae to vancomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345591"}
{"pmid": "4345592", "title": "Dynamic ultrastructure of presynaptic membranes at nerve terminals in the spinal cord of rats. Anesthetized and unanesthetized preparations compared.", "content": "Dynamic ultrastructure of presynaptic membranes at nerve terminals in the spinal cord of rats. Anesthetized and unanesthetized preparations compared.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345592"}
{"pmid": "4345593", "title": "Centrifugal control of the avian retina. IV. Effects of reversible cold block of the isthmo-optic tract on the receptive field properties of cells in the retina and isthmo-optic nucleus.", "content": "Centrifugal control of the avian retina. IV. Effects of reversible cold block of the isthmo-optic tract on the receptive field properties of cells in the retina and isthmo-optic nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345593"}
{"pmid": "4345594", "title": "Intracellular study of the cat's primary auditory cortex.", "content": "Intracellular study of the cat's primary auditory cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345594"}
{"pmid": "4345595", "title": "The role of acetylcholine in the intracerebellar nuclei of the cat.", "content": "The role of acetylcholine in the intracerebellar nuclei of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345595"}
{"pmid": "4345596", "title": "Anatomical studies of the organization of the spinal V nucleus: the deep bundles and the spinal V tract.", "content": "Anatomical studies of the organization of the spinal V nucleus: the deep bundles and the spinal V tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345596"}
{"pmid": "4345598", "title": "The effects of reticular stimulation on the firing rate of neurons in the pericruciate cortex of cats.", "content": "The effects of reticular stimulation on the firing rate of neurons in the pericruciate cortex of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345598"}
{"pmid": "4345599", "title": "Electrophysiological properties of neuronal circuits in the frog cerebellum in vitro.", "content": "Electrophysiological properties of neuronal circuits in the frog cerebellum in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345599"}
{"pmid": "4345600", "title": "Motor cortex modulation of knee flexor and extensor fusimotor neurons in the 'pyramidal' cat.", "content": "Motor cortex modulation of knee flexor and extensor fusimotor neurons in the 'pyramidal' cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345600"}
{"pmid": "4345601", "title": "Neurochemical bases of the PGO wave.", "content": "Neurochemical bases of the PGO wave.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345601"}
{"pmid": "4345602", "title": "Dependence of REM sleep PGO waves on cholinergic mechanisms.", "content": "Dependence of REM sleep PGO waves on cholinergic mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345602"}
{"pmid": "4345603", "title": "Evidence of cholinergic mediation of ingestive responses elicited by dibutyryladenosine-3',5'-monophosphate in rat hypothalamus.", "content": "Evidence of cholinergic mediation of ingestive responses elicited by dibutyryladenosine-3',5'-monophosphate in rat hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345603"}
{"pmid": "4345604", "title": "Serotonin turnover in cultured raphe nuclei from newborn rat: in vitro development and drug effects.", "content": "Serotonin turnover in cultured raphe nuclei from newborn rat: in vitro development and drug effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345604"}
{"pmid": "4345605", "title": "Infiltrating lobular carcinoma of the breast.", "content": "Infiltrating lobular carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345605"}
{"pmid": "4345606", "title": "Tumors of minor salivary origin. A clinicopathologic study of 492 cases.", "content": "Tumors of minor salivary origin. A clinicopathologic study of 492 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345606"}
{"pmid": "4345607", "title": "Mammary duct proliferation in the elderly. A histopathologic study.", "content": "Mammary duct proliferation in the elderly. A histopathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345607"}
{"pmid": "4345608", "title": "Familial occurrence of extramammary Paget's disease.", "content": "Familial occurrence of extramammary Paget's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345608"}
{"pmid": "4345609", "title": "Electrocoagulation and curettage for carcinoma involving the skin of the face, nose, eyelids, and ears.", "content": "Electrocoagulation and curettage for carcinoma involving the skin of the face, nose, eyelids, and ears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345609"}
{"pmid": "4345610", "title": "Adenocarcinoma of Bartholin's gland associated with Paget's disease of vulvar area.", "content": "Adenocarcinoma of Bartholin's gland associated with Paget's disease of vulvar area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345610"}
{"pmid": "4345611", "title": "Carcinoma of large intestine in patients irradiated for carcinoma of cervix and uterus.", "content": "Carcinoma of large intestine in patients irradiated for carcinoma of cervix and uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345611"}
{"pmid": "4345612", "title": "Reappraisal of surgical management of sarcoma of the buttock.", "content": "Reappraisal of surgical management of sarcoma of the buttock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345612"}
{"pmid": "4345615", "title": "A study of serum lipoprotein electrophoresis on cellogel: normal values, comparison with SML profiling and ultracentrifugation.", "content": "A study of serum lipoprotein electrophoresis on cellogel: normal values, comparison with SML profiling and ultracentrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345615"}
{"pmid": "4345616", "title": "Determination of serum guanase by means of a NADH-linked reaction.", "content": "Determination of serum guanase by means of a NADH-linked reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345616"}
{"pmid": "4345618", "title": "Enzymatic determination of ammonia in blood plasma.", "content": "Enzymatic determination of ammonia in blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345618"}
{"pmid": "4345617", "title": "A non-mercurimetric automated method for serum chloride.", "content": "A non-mercurimetric automated method for serum chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345617"}
{"pmid": "4345621", "title": "A short, retarded child with a deletion of the short arm of chromosome 18 (18p-).", "content": "A short, retarded child with a deletion of the short arm of chromosome 18 (18p-).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345621"}
{"pmid": "4345623", "title": "Polygraphic study of dyssynergia cerebellaris myoclonica (Ramsay-Hunt syndrome) and of the intention myoclonus (Lance-Adams syndrome) during sleep.", "content": "Polygraphic study of dyssynergia cerebellaris myoclonica (Ramsay-Hunt syndrome) and of the intention myoclonus (Lance-Adams syndrome) during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345623"}
{"pmid": "4345620", "title": "The phospholipids of the thyroid gland.", "content": "The phospholipids of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345620"}
{"pmid": "4345625", "title": "An evaluation of the course of peripheral neuropathies based on clinical and neurographical re-examinations.", "content": "An evaluation of the course of peripheral neuropathies based on clinical and neurographical re-examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345625"}
{"pmid": "4345624", "title": "Neuro-Behçet's syndrome in the United Arab Republic.", "content": "Neuro-Behçet's syndrome in the United Arab Republic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345624"}
{"pmid": "4345626", "title": "Determination of human chronological age by study of a collagen sample.", "content": "Determination of human chronological age by study of a collagen sample.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345626"}
{"pmid": "4345627", "title": "Changes in collagen with age. IV. The extraction of soluble collagen from human lung.", "content": "Changes in collagen with age. IV. The extraction of soluble collagen from human lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345627"}
{"pmid": "4345628", "title": "Intracisternal A-type and C-type particles observed in pulmonary tumors in mice.", "content": "Intracisternal A-type and C-type particles observed in pulmonary tumors in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345628"}
{"pmid": "4345629", "title": "High yield of hepatic tumors in rats by cycasin.", "content": "High yield of hepatic tumors in rats by cycasin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345629"}
{"pmid": "4345622", "title": "Ampicillin and hetacillin pharmacokinetics in normal and anephric subjects.", "content": "Ampicillin and hetacillin pharmacokinetics in normal and anephric subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345622"}
{"pmid": "4345631", "title": "Serum glycoprotein levels in the rat bearing ascites hepatoma 109A.", "content": "Serum glycoprotein levels in the rat bearing ascites hepatoma 109A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345631"}
{"pmid": "4345630", "title": "A hetero-organic antigen of a rat ascites hepatoma.", "content": "A hetero-organic antigen of a rat ascites hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345630"}
{"pmid": "4345632", "title": "An immuno-electron microscopic analysis of Epstein-Barr virus-related antigens in Burkitt lymphoma cells.", "content": "An immuno-electron microscopic analysis of Epstein-Barr virus-related antigens in Burkitt lymphoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345632"}
{"pmid": "4345634", "title": "Predicting the course of adenoid cystic carcinoma.", "content": "Predicting the course of adenoid cystic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345634"}
{"pmid": "4345638", "title": "Fine-needle aspiration biopsy of the liver in hepatic malignancy.", "content": "Fine-needle aspiration biopsy of the liver in hepatic malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345638"}
{"pmid": "4345637", "title": "The effect of hypertonic media on water permeability of frog urinary bladder. Inhibition by catecholamines and prostaglandin E 1 .", "content": "The effect of hypertonic media on water permeability of frog urinary bladder. Inhibition by catecholamines and prostaglandin E 1 . The frog urinary bladder undergoes, in some conditions, a marked increase of its water permeability when incubated in hypertonic media. This increase was observed with various nonpermeant solutes. It seems to result from the shrinkage of an osmo-sensitive compartment of the tissue, probably the epithelial cells. Many similarities were found between this effect and the physiological increase in water permeability (hydrosmotic response) elicited by antidiuretic hormone (ADH): both were dependent on the physiological state of the animals, and although the response was slower after hyperosmolar than after hormonal challenge, the patterns of response were similar, and in both cases markedly dependent on bathing solution temperature. Norepinephrine and prostaglandin E(1), which in this tissue reduce the hydrosmotic action of ADH, presumably by inhibiting the adenyl cylase also reduced the effect of hyperosmolarity. Conversely this effect was potentiated by incubation in the presence of oxytocin, exogenous cyclic AMP, and theophylline, conditions in which the intracellular concentration of cyclic AMP is increased. These data demonstrate that the response to hyperosmolarity is elicited, at least partly, by mechanisms also involved in the physiological hydrosmotic response to ADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345637"}
{"pmid": "4345639", "title": "Antimetabolites of coenzyme Q. 16. New alkylmercaptoquinones having antimalarial curative activity.", "content": "Antimetabolites of coenzyme Q. 16. New alkylmercaptoquinones having antimalarial curative activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345639"}
{"pmid": "4345640", "title": "Isolation and renin-inhibitory activity of phosphoglyceride from shark kidney.", "content": "Isolation and renin-inhibitory activity of phosphoglyceride from shark kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345640"}
{"pmid": "4345641", "title": "A working hypothesis explaining the maintenance of the transformed state by SV40 and polyoma.", "content": "A working hypothesis explaining the maintenance of the transformed state by SV40 and polyoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345641"}
{"pmid": "4345643", "title": "Instability of a layer of chemotactic cells, attractant and degrading enzyme.", "content": "Instability of a layer of chemotactic cells, attractant and degrading enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345643"}
{"pmid": "4345644", "title": "Oral carcinoma in the first three decades of life.", "content": "Oral carcinoma in the first three decades of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345644"}
{"pmid": "4345642", "title": "The prostatic cell DNA-steroid association: a hypothesis of nuclear events and cytoplasmic consequences.", "content": "The prostatic cell DNA-steroid association: a hypothesis of nuclear events and cytoplasmic consequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345642"}
{"pmid": "4345645", "title": "Antibodies to EBV related antigens in West Malaysian children.", "content": "Antibodies to EBV related antigens in West Malaysian children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345645"}
{"pmid": "4345647", "title": "A case of glomus jugulare tumour.", "content": "A case of glomus jugulare tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345647"}
{"pmid": "4345646", "title": "Cellular and hormonal control in glycogen metabolism--recent advances.", "content": "Cellular and hormonal control in glycogen metabolism--recent advances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345646"}
{"pmid": "4345648", "title": "Electron microscopic studies on various types of inclusions found in autopsy cases. I. A new type of nuclear inclusion in the liver of polyradiculoneuritis.", "content": "Electron microscopic studies on various types of inclusions found in autopsy cases. I. A new type of nuclear inclusion in the liver of polyradiculoneuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345648"}
{"pmid": "4345653", "title": "Physical studies of membrane structure.", "content": "Physical studies of membrane structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345653"}
{"pmid": "4345654", "title": "Efficacy of psychiatric rehabilitation.", "content": "Efficacy of psychiatric rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345654"}
{"pmid": "4345657", "title": "Sleep and memory.", "content": "Sleep and memory. Two experiments demonstrated that memory over an interval with relatively high amounts of rapid eye movement (REM) sleep was inferior to memory over an interval with relatively high amounts of stage 4 sleep. The results suggest that, at least for humans, REM sleep does not facilitate memory consolidation and that stage 4 sleep may be beneficial to memory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345657"}
{"pmid": "4345658", "title": "A theory and physical model for chochlear mechanics.", "content": "A theory and physical model for chochlear mechanics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345658"}
{"pmid": "4345650", "title": "Absorption of \"penetrating\" anions by hydrophobic parts of macromolecules.", "content": "Absorption of \"penetrating\" anions by hydrophobic parts of macromolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345650"}
{"pmid": "4345659", "title": "Tablet sensitivity testing: a comparison of different methods.", "content": "Tablet sensitivity testing: a comparison of different methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345659"}
{"pmid": "4345660", "title": "Some characteristics of the A antigen in Marek's disease virus--infected cell cultures.", "content": "Some characteristics of the A antigen in Marek's disease virus--infected cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345660"}
{"pmid": "4345661", "title": "A micro assay for mouse and human interferon.", "content": "A micro assay for mouse and human interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345661"}
{"pmid": "4345662", "title": "Fine structure of melanin-producing aeromonads.", "content": "Fine structure of melanin-producing aeromonads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345662"}
{"pmid": "4345663", "title": "On the adsorption of Australia antigen to a colloidal silica, and some possible applications.", "content": "On the adsorption of Australia antigen to a colloidal silica, and some possible applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345663"}
{"pmid": "4345664", "title": "Drug and sociotherapy in the aftercare of schizophrenic patients. One-year relapse rates.", "content": "Drug and sociotherapy in the aftercare of schizophrenic patients. One-year relapse rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345664"}
{"pmid": "4345651", "title": "Investigation of the conformational properties of aspartate aminotransferase molecules by the spin-tag method.", "content": "Investigation of the conformational properties of aspartate aminotransferase molecules by the spin-tag method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345651"}
{"pmid": "4345665", "title": "Faliure to demonstrate desmosterol in spinal fluid of brain tumor patients.", "content": "Faliure to demonstrate desmosterol in spinal fluid of brain tumor patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345665"}
{"pmid": "4345666", "title": "Granular cells in tumors and in nontumorous tissue.", "content": "Granular cells in tumors and in nontumorous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345666"}
{"pmid": "4345668", "title": "The effect of cholera toxin on the phosphorylation of protein in epithelial cells and their brush borders.", "content": "The effect of cholera toxin on the phosphorylation of protein in epithelial cells and their brush borders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345668"}
{"pmid": "4345667", "title": "Subacute sclerosing panencephalitis. Immunoultrastructural localization of measles-virus antigen.", "content": "Subacute sclerosing panencephalitis. Immunoultrastructural localization of measles-virus antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345667"}
{"pmid": "4345669", "title": "The \"oxygenated complex\" of cytochrome c oxidase.", "content": "The \"oxygenated complex\" of cytochrome c oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345669"}
{"pmid": "4345670", "title": "Increases in rat liver cyclic AMP concentrations prior to the initiation of DNA synthesis following partial hepatectomy or hormone infusion.", "content": "Increases in rat liver cyclic AMP concentrations prior to the initiation of DNA synthesis following partial hepatectomy or hormone infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345670"}
{"pmid": "4345671", "title": "Kinetics of reconstitutioin of polyphenoloxidase from apoenzyme and copper.", "content": "Kinetics of reconstitutioin of polyphenoloxidase from apoenzyme and copper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345671"}
{"pmid": "4345652", "title": "Investigation of photoprocesses in aromatic peptides by the method of electron paramagnetic resonance.", "content": "Investigation of photoprocesses in aromatic peptides by the method of electron paramagnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345652"}
{"pmid": "4345672", "title": "The identification and characterization of a cyclic AMP dependent protein kinase on rabbit reticulocyte ribosomes.", "content": "The identification and characterization of a cyclic AMP dependent protein kinase on rabbit reticulocyte ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345672"}
{"pmid": "4345673", "title": "Sialyl transferase activity in normal and RNA- and DNA-virus transformed cells utilizing desialyzed, trypsinized cell plasma membrane external surface glycoproteins as exogenous acceptors.", "content": "Sialyl transferase activity in normal and RNA- and DNA-virus transformed cells utilizing desialyzed, trypsinized cell plasma membrane external surface glycoproteins as exogenous acceptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345673"}
{"pmid": "4345674", "title": "The fluorescence behaviour of 1-anilino-8-naphthalene sulphonate in phospholipid and natural membranes.", "content": "The fluorescence behaviour of 1-anilino-8-naphthalene sulphonate in phospholipid and natural membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345674"}
{"pmid": "4345675", "title": "Isolated adrenal cortex cells: (Trp(Dnps) 9 )ACTH 5  -24 , an inhibitor of ACTH 1-24 -induced cyclic AMP and corticosterone production.", "content": "Isolated adrenal cortex cells: (Trp(Dnps) 9 )ACTH 5  -24 , an inhibitor of ACTH 1-24 -induced cyclic AMP and corticosterone production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345675"}
{"pmid": "4345676", "title": "Transmural and subcellular localization of monoamine oxidase and catechol-0-methyl transferase in rabbit aorta.", "content": "Transmural and subcellular localization of monoamine oxidase and catechol-0-methyl transferase in rabbit aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345676"}
{"pmid": "4345677", "title": "Interaction of chloropromazine with adrenochrome and interference of a possible endogenous psychotogenic agent with some synaptic enzyme activities.", "content": "Interaction of chloropromazine with adrenochrome and interference of a possible endogenous psychotogenic agent with some synaptic enzyme activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345677"}
{"pmid": "4345678", "title": "Isolation and identification of a renin inhibitor form ox bile.", "content": "Isolation and identification of a renin inhibitor form ox bile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345678"}
{"pmid": "4345685", "title": "Assisting patients with posthospitalization plans.", "content": "Assisting patients with posthospitalization plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345685"}
{"pmid": "4345686", "title": "Coupled layers: a new technique for the two-dimensional thin-layer chromatography of carbohydrates.", "content": "Coupled layers: a new technique for the two-dimensional thin-layer chromatography of carbohydrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345686"}
{"pmid": "4345689", "title": "A method for the determination of Venzar (3-cyclohexyl-5,6-trimethyluracil) on silica gel layers.", "content": "A method for the determination of Venzar (3-cyclohexyl-5,6-trimethyluracil) on silica gel layers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345689"}
{"pmid": "4345690", "title": "Effect of upright posture and isoproterenol infusion on cyclic adenosine monophosphate excretion in control subjects and patients with labile hypertension.", "content": "Effect of upright posture and isoproterenol infusion on cyclic adenosine monophosphate excretion in control subjects and patients with labile hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345690"}
{"pmid": "4345691", "title": "Lack of responsiveness to L-dopa in Cushing's disease.", "content": "Lack of responsiveness to L-dopa in Cushing's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345691"}
{"pmid": "4345692", "title": "Control of hypoglycemia with L-asparaginase in a patient with islet cell cancer.", "content": "Control of hypoglycemia with L-asparaginase in a patient with islet cell cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345692"}
{"pmid": "4345693", "title": "Peroxidase defect in congenital goiter with complete organification block.", "content": "Peroxidase defect in congenital goiter with complete organification block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345693"}
{"pmid": "4345694", "title": "Control of aldosterone secretion in hyperthyroidism.", "content": "Control of aldosterone secretion in hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345694"}
{"pmid": "4345696", "title": "Thickness and area measurements as parameters of skeletal involution of the humerus, femur, and tibia.", "content": "Thickness and area measurements as parameters of skeletal involution of the humerus, femur, and tibia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345696"}
{"pmid": "4345697", "title": "Relationship of radiographic cortical thickness vs. age in thirteen bones of the hand.", "content": "Relationship of radiographic cortical thickness vs. age in thirteen bones of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345697"}
{"pmid": "4345698", "title": "Studies on nitroxide spin-labeled poly- -benzyl- ,L-glutamate.", "content": "Studies on nitroxide spin-labeled poly- -benzyl- ,L-glutamate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345698"}
{"pmid": "4345695", "title": "Serotonin and inhibition in Limulus lateral eye.", "content": "Serotonin and inhibition in Limulus lateral eye. The response to light of one ommatidium is reduced or suppressed by simultaneous illumination of neighboring ommatidia. The mechanism of this lateral inhibition may be chemical synaptic transmission, based on the physiological findings of a number of investigators and on the following evidence. The fine structure of the neuropil of the lateral plexus exhibits numerous clear vesicles (ca. 400 A), dense-core vesicles (ca. 700-1400 A), Golgi regions, and other morphological features of neurochemical synapses. The indolealkylamine, serotonin (5-HT), even in nanomolar concentrations, has a potent inhibitory action. An initial, potent inhibitory dose of 5-HT produces a long lasting densensitization to subsequent doses. The desensitization affects lateral inhibition evoked by light stimulation of neighboring receptors, i.e. crossed-desensitization. Eye tissue extracts contain 5-HT and melatonin (MLT) at a level greater than 1 microg/g wet tissue and perhaps as high as 20-30 microg/g, as determined by two-dimensional thin-layer chromatography (TLC) and o-phthaldialdehyde fluorescence assay techniques. Subcellular fractionation on sucrose gradient indicates a peak in 5-HT and MLT content associated with an intermediate density fraction. 5-HT may be an inhibitory transmitter for lateral inhibition. One pathway for metabolism of 5-HT in the lateral eye may be via N-acetylserotonin and melatonin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345695"}
{"pmid": "4345699", "title": "Follow-up care after hospitalization. Health center vs hospital.", "content": "Follow-up care after hospitalization. Health center vs hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345699"}
{"pmid": "4345701", "title": "Effects of dibutyryl cyclic adenosine phosphate plus theophylline on murine sarcoma virus transformed non-producer cells.", "content": "Effects of dibutyryl cyclic adenosine phosphate plus theophylline on murine sarcoma virus transformed non-producer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345701"}
{"pmid": "4345703", "title": "Induction of antinuclear antibodies in (CxB6) F1 mice inoculated with Graffi and Rauscher leukemogenic viruses.", "content": "Induction of antinuclear antibodies in (CxB6) F1 mice inoculated with Graffi and Rauscher leukemogenic viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345703"}
{"pmid": "4345702", "title": "Some aspects of the tubular locus of the natriuretic action of vasoactive drugs.", "content": "Some aspects of the tubular locus of the natriuretic action of vasoactive drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345702"}
{"pmid": "4345705", "title": "Study of immune cytotoxicity with Herpesvirus hominis infected cells.", "content": "Study of immune cytotoxicity with Herpesvirus hominis infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345705"}
{"pmid": "4345704", "title": "Herpes simplex virus replication in human lymphocyte cultures stimulated with phytomitogens and anti-lymphocyte globulin.", "content": "Herpes simplex virus replication in human lymphocyte cultures stimulated with phytomitogens and anti-lymphocyte globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345704"}
{"pmid": "4345706", "title": "Interferon induction in normal leukemic human lymphocyte cultures by tilorone hydrochloride.", "content": "Interferon induction in normal leukemic human lymphocyte cultures by tilorone hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345706"}
{"pmid": "4345707", "title": "Variations in the interferogenic responses of two strains of mice.", "content": "Variations in the interferogenic responses of two strains of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345707"}
{"pmid": "4345708", "title": "The form of absorption of lipids in the chicken, Gallus domesticus.", "content": "The form of absorption of lipids in the chicken, Gallus domesticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345708"}
{"pmid": "4345709", "title": "Heterogeneity of human plasma high density lipoprotein.", "content": "Heterogeneity of human plasma high density lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345709"}
{"pmid": "4345710", "title": "Roles of aortic and carotid chemoreceptors in activating the hypothalamo-hypophyseal-adrenocortical system during hypoxia.", "content": "Roles of aortic and carotid chemoreceptors in activating the hypothalamo-hypophyseal-adrenocortical system during hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345710"}
{"pmid": "4345711", "title": "Comparative effects of hypoxia, adrenocorticotropin and methylcholine on adrenocortical secretory rates.", "content": "Comparative effects of hypoxia, adrenocorticotropin and methylcholine on adrenocortical secretory rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345711"}
{"pmid": "4345712", "title": "Effect of methylprednisolone in epinephrine-thyroxine induced arteriosclerosis.", "content": "Effect of methylprednisolone in epinephrine-thyroxine induced arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345712"}
{"pmid": "4345713", "title": "Interferon inhibition by narcotic analgesics.", "content": "Interferon inhibition by narcotic analgesics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345713"}
{"pmid": "4345714", "title": "Blocking of interferon production by chromatographically purified L cell interferon.", "content": "Blocking of interferon production by chromatographically purified L cell interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345714"}
{"pmid": "4345716", "title": "Effect of a converting enzyme inhibitor (SQ 20,881) on angiotensin-induced drinking.", "content": "Effect of a converting enzyme inhibitor (SQ 20,881) on angiotensin-induced drinking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345716"}
{"pmid": "4345715", "title": "A simple method for the growth of mouse neuron monolayer cultures.", "content": "A simple method for the growth of mouse neuron monolayer cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345715"}
{"pmid": "4345717", "title": "Adipose and liver tissue enzyme profiles in obese hyperglycemic mice.", "content": "Adipose and liver tissue enzyme profiles in obese hyperglycemic mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345717"}
{"pmid": "4345718", "title": "Inhibition of protocollagen proline hydroxylase by Dilantin.", "content": "Inhibition of protocollagen proline hydroxylase by Dilantin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345718"}
{"pmid": "4345719", "title": "Interferon antagonists induced by Newcastle disease virus (NDV).", "content": "Interferon antagonists induced by Newcastle disease virus (NDV).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345719"}
{"pmid": "4345720", "title": "Differentiation of types 1 and 2 herpes simplex virus by plaque inhibition with sulfated polyanions.", "content": "Differentiation of types 1 and 2 herpes simplex virus by plaque inhibition with sulfated polyanions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345720"}
{"pmid": "4345721", "title": "Binding of angiotensin I and angiotensin II to plasma proteins precipitated by ammonium sulfate.", "content": "Binding of angiotensin I and angiotensin II to plasma proteins precipitated by ammonium sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345721"}
{"pmid": "4345722", "title": "The role of angiotensin II in a pressor response to nicotine after phenoxybenzamine.", "content": "The role of angiotensin II in a pressor response to nicotine after phenoxybenzamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345722"}
{"pmid": "4345723", "title": "Stimulation of angiotensinogen formation by renin and angiotensin.", "content": "Stimulation of angiotensinogen formation by renin and angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345723"}
{"pmid": "4345724", "title": "The production of human leukocyte interferon in a serum-free medium.", "content": "The production of human leukocyte interferon in a serum-free medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345724"}
{"pmid": "4345725", "title": "Interferon and cell division. VII. Inhibitory effect of highly purified interferon preparations on the multiplication of leukemia L 1210 cells.", "content": "Interferon and cell division. VII. Inhibitory effect of highly purified interferon preparations on the multiplication of leukemia L 1210 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345725"}
{"pmid": "4345726", "title": "Histochemical study of the effect of a deuteron beam on the dental germ.", "content": "Histochemical study of the effect of a deuteron beam on the dental germ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345726"}
{"pmid": "4345727", "title": "In vitro evaluation of enzymatic debridement of burn wound eschar.", "content": "In vitro evaluation of enzymatic debridement of burn wound eschar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345727"}
{"pmid": "4345728", "title": "Aspiration cytology in carcinoma of the pancreas.", "content": "Aspiration cytology in carcinoma of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345728"}
{"pmid": "4345730", "title": "A summary of the status of de novo cancer in transplant recipients.", "content": "A summary of the status of de novo cancer in transplant recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345730"}
{"pmid": "4345729", "title": "The effect of ACTH on corticosteroid concentration in monkey bile, as measured by competitive protein-binding analysis.", "content": "The effect of ACTH on corticosteroid concentration in monkey bile, as measured by competitive protein-binding analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345729"}
{"pmid": "4345732", "title": "Liver transplantation.", "content": "Liver transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345732"}
{"pmid": "4345731", "title": "Personal experience with orthotopic liver transplantation.", "content": "Personal experience with orthotopic liver transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345731"}
{"pmid": "4345736", "title": "Cyclic AMP in the regulation of gastric secretion in dogs and humans.", "content": "Cyclic AMP in the regulation of gastric secretion in dogs and humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345736"}
{"pmid": "4345738", "title": "Reinforcement of reflex epinephrine release by angiotensin II.", "content": "Reinforcement of reflex epinephrine release by angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345738"}
{"pmid": "4345737", "title": "Amino acid transport in bone: stimulation by cyclic AMP.", "content": "Amino acid transport in bone: stimulation by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345737"}
{"pmid": "4345739", "title": "Carboxylate modification of neuromuscular transmission in the frog.", "content": "Carboxylate modification of neuromuscular transmission in the frog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345739"}
{"pmid": "4345744", "title": "Responses of isolated monkey umbilical veins to biogenic amines and polypeptides.", "content": "Responses of isolated monkey umbilical veins to biogenic amines and polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345744"}
{"pmid": "4345743", "title": "A comparison of influenza and parainfluenza and RNP properties.", "content": "A comparison of influenza and parainfluenza and RNP properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345743"}
{"pmid": "4345742", "title": "Induction of interferon and host resistance in vivo by double-stranded complexes of copolyribonucleotide of isosinic and guanylic with polyribocytidylic acid.", "content": "Induction of interferon and host resistance in vivo by double-stranded complexes of copolyribonucleotide of isosinic and guanylic with polyribocytidylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345742"}
{"pmid": "4345745", "title": "Action of angiotensin and plasmakinins on blood flow through the mammary artery in lactating small ruminants.", "content": "Action of angiotensin and plasmakinins on blood flow through the mammary artery in lactating small ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345745"}
{"pmid": "4345747", "title": "(2- 14 C) ethanol as a precursor of glutamine, glutamate, -aminobutyric acid and aspartate in hamster brain in vivo.", "content": "(2- 14 C) ethanol as a precursor of glutamine, glutamate, -aminobutyric acid and aspartate in hamster brain in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345747"}
{"pmid": "4345748", "title": "Mode of action of 5,5'-diphenylthiohydantoin-sites of action of 5,5'-diphenylthiohydantoin in mitochondria in relationship to thyroxine-stimulated responses.", "content": "Mode of action of 5,5'-diphenylthiohydantoin-sites of action of 5,5'-diphenylthiohydantoin in mitochondria in relationship to thyroxine-stimulated responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345748"}
{"pmid": "4345750", "title": "Significance of the LP-X test in differential diagnosis of jaundice.", "content": "Significance of the LP-X test in differential diagnosis of jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345750"}
{"pmid": "4345752", "title": "Effect of diazoxide on golden hamsters with chronic hypoglycemia due to a transplantable islet-cell tumor.", "content": "Effect of diazoxide on golden hamsters with chronic hypoglycemia due to a transplantable islet-cell tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345752"}
{"pmid": "4345753", "title": "The influence of blood glucose on ACTH secretion in man.", "content": "The influence of blood glucose on ACTH secretion in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345753"}
{"pmid": "4345754", "title": "Effects of metopirone on urinary excretion of adrenaline, noradrenaline and vanylmandelic acid in different physiological conditions. The possible role of adrenal cortex in catecholamine degradation.", "content": "Effects of metopirone on urinary excretion of adrenaline, noradrenaline and vanylmandelic acid in different physiological conditions. The possible role of adrenal cortex in catecholamine degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345754"}
{"pmid": "4345756", "title": "Calcitonin secretion in medullary carcinoma of the thyroid.", "content": "Calcitonin secretion in medullary carcinoma of the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345756"}
{"pmid": "4345755", "title": "On the effect of synthetic LH-releasing hormone on the blood levels of LH, FSH, HGH, TSH, ACTH, insulin and blood sugar in man.", "content": "On the effect of synthetic LH-releasing hormone on the blood levels of LH, FSH, HGH, TSH, ACTH, insulin and blood sugar in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345755"}
{"pmid": "4345757", "title": "The formation and distribution of cyclic 3',5'-adenosine monophosphate in the everted guinea pig seminal vesicle sac.", "content": "The formation and distribution of cyclic 3',5'-adenosine monophosphate in the everted guinea pig seminal vesicle sac.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345757"}
{"pmid": "4345758", "title": "Virus-induced genitourinary malignancy. Macromolecular identity.", "content": "Virus-induced genitourinary malignancy. Macromolecular identity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345758"}
{"pmid": "4345759", "title": "Laboratory production and  14 C-labelling of viomycin.", "content": "Laboratory production and  14 C-labelling of viomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345759"}
{"pmid": "4345761", "title": "Regulation of insulin secretion in the ovine foetus in utero. Effects of sodium valerate on secretion and of adrenocorticotrophin-induced premature parturition on the insulin secretory response to glucose.", "content": "Regulation of insulin secretion in the ovine foetus in utero. Effects of sodium valerate on secretion and of adrenocorticotrophin-induced premature parturition on the insulin secretory response to glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345761"}
{"pmid": "4345762", "title": "Lipolysis and adenosine 3',5'-cyclic monophosphate in adipose tissue of the New Zealand obese mouse.", "content": "Lipolysis and adenosine 3',5'-cyclic monophosphate in adipose tissue of the New Zealand obese mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345762"}
{"pmid": "4345763", "title": "Effect of sleep on memory. 3. Controlling for time-of-day effects.", "content": "Effect of sleep on memory. 3. Controlling for time-of-day effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345763"}
{"pmid": "4345764", "title": "The hyperphosphatemic effect of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP TM ): renal handling of phosphorus and the renal response to parathyroid hormone.", "content": "The hyperphosphatemic effect of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP TM ): renal handling of phosphorus and the renal response to parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345764"}
{"pmid": "4345765", "title": "The pathology and immunology of Bordetella pertussis infection.", "content": "The pathology and immunology of Bordetella pertussis infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345765"}
{"pmid": "4345766", "title": "The prevention of experimental Clostridium novyi and Cl. perfringens gas gangrene in high-velocity missile wounds by active immunisation.", "content": "The prevention of experimental Clostridium novyi and Cl. perfringens gas gangrene in high-velocity missile wounds by active immunisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345766"}
{"pmid": "4345760", "title": "Petrographic study of the refractory performance of high-fusing dental alloy investments. I. High-fired, phosphate-bonded investments.", "content": "Petrographic study of the refractory performance of high-fusing dental alloy investments. I. High-fired, phosphate-bonded investments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345760"}
{"pmid": "4345767", "title": "The effect of the medium and source of growth factors on the satellitism test for Haemophilus species.", "content": "The effect of the medium and source of growth factors on the satellitism test for Haemophilus species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345767"}
{"pmid": "4345769", "title": "The epidemiology of tanapox and yaba virus infections.", "content": "The epidemiology of tanapox and yaba virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345769"}
{"pmid": "4345768", "title": "An electron-microscopic study of intracerebral infection of mice with low-virulence Bordetella pertussis.", "content": "An electron-microscopic study of intracerebral infection of mice with low-virulence Bordetella pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345768"}
{"pmid": "4345770", "title": "Steroid metabolism in the adrenals of fetal sheep in relation to natural and corticotrophin-induced parturition.", "content": "Steroid metabolism in the adrenals of fetal sheep in relation to natural and corticotrophin-induced parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345770"}
{"pmid": "4345771", "title": "Parturition in the goat and sheep: changes in corticosteroids, progesterone, oestrogens and prostaglandin F.", "content": "Parturition in the goat and sheep: changes in corticosteroids, progesterone, oestrogens and prostaglandin F.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345771"}
{"pmid": "4345772", "title": "The physiological rôles of progesterone, oestradiol-17  and prostaglandin F 2   in the control of ovine parturition.", "content": "The physiological rôles of progesterone, oestradiol-17  and prostaglandin F 2   in the control of ovine parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345772"}
{"pmid": "4345788", "title": "Determination of steady-state concentrations of adenine nucleotides in growing C. kluyveri cells by biosynthetic labeling.", "content": "Determination of steady-state concentrations of adenine nucleotides in growing C. kluyveri cells by biosynthetic labeling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345788"}
{"pmid": "4345786", "title": "Chronic active hepatitis and Graves' disease.", "content": "Chronic active hepatitis and Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345786"}
{"pmid": "4345787", "title": "Determination of N-(9-( -D-ribofuranosyl)purin-6-ylcarbamoly)threonine at the picomole level in transfer-RNA.", "content": "Determination of N-(9-( -D-ribofuranosyl)purin-6-ylcarbamoly)threonine at the picomole level in transfer-RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345787"}
{"pmid": "4345789", "title": "Advantages of the use of Cerenkov vounting for determination of P 32  in photophosphorylation research.", "content": "Advantages of the use of Cerenkov vounting for determination of P 32  in photophosphorylation research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345789"}
{"pmid": "4345790", "title": "Method for rapid isolation of free aminoacyl-transfer RNA.", "content": "Method for rapid isolation of free aminoacyl-transfer RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345790"}
{"pmid": "4345791", "title": "Agarose gel electrophoresis of serum lipoproteins: determination of true mobility, isoelectric point, and molecular size.", "content": "Agarose gel electrophoresis of serum lipoproteins: determination of true mobility, isoelectric point, and molecular size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345791"}
{"pmid": "4345792", "title": "Simple and sensitive photometric recycling assay for nicotinamide-adenine dinucleotide.", "content": "Simple and sensitive photometric recycling assay for nicotinamide-adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345792"}
{"pmid": "4345801", "title": "The effect of cyclic adenosine- and guanosine 3',5'-monophosphate on the normal and drug-increased coronary blood flow.", "content": "The effect of cyclic adenosine- and guanosine 3',5'-monophosphate on the normal and drug-increased coronary blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345801"}
{"pmid": "4345802", "title": "Phosphodiesterase inhibition by papaverine and structurally related compounds.", "content": "Phosphodiesterase inhibition by papaverine and structurally related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345802"}
{"pmid": "4345804", "title": "Transcription of ribonucleic acid by the ribonucleic acid directed deoxyribonucleic acid polymerase of Rous sarcoma virus and deoxyribonucleic acid polymerase I of Escherichia coli.", "content": "Transcription of ribonucleic acid by the ribonucleic acid directed deoxyribonucleic acid polymerase of Rous sarcoma virus and deoxyribonucleic acid polymerase I of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345804"}
{"pmid": "4345803", "title": "Butyl isocyanate, an active-site-specific reagent for yeast alcohol dehydrogenase.", "content": "Butyl isocyanate, an active-site-specific reagent for yeast alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345803"}
{"pmid": "4345806", "title": "Heterogeneity of human plasma very low density lipoproteins. Separation of species differing in protein components.", "content": "Heterogeneity of human plasma very low density lipoproteins. Separation of species differing in protein components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345806"}
{"pmid": "4345805", "title": "Purification and kinetic properties of Neurospora transfer ribonucleic acid nucleotidyltransferase.", "content": "Purification and kinetic properties of Neurospora transfer ribonucleic acid nucleotidyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345805"}
{"pmid": "4345807", "title": "The role of phospholipid in succinate cytochrome c reductase.", "content": "The role of phospholipid in succinate cytochrome c reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345807"}
{"pmid": "4345808", "title": "Phosphate transfer from adenosine triphosphate in a model system.", "content": "Phosphate transfer from adenosine triphosphate in a model system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345808"}
{"pmid": "4345809", "title": "Tissue reactions to the three root canal medicaments.", "content": "Tissue reactions to the three root canal medicaments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345809"}
{"pmid": "4345811", "title": "The effects of polyvinyl pyridine-N-oxide (P204) on the cytopathogenic action of chrysotile asbestos in vivo and in vitro.", "content": "The effects of polyvinyl pyridine-N-oxide (P204) on the cytopathogenic action of chrysotile asbestos in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345811"}
{"pmid": "4345810", "title": "Sendai (parainfluenza 1) infection of mouse eggs.", "content": "Sendai (parainfluenza 1) infection of mouse eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345810"}
{"pmid": "4345812", "title": "A quantitative investigation of the effects on the growth of calcium oxalate crystals on potential inhibitors.", "content": "A quantitative investigation of the effects on the growth of calcium oxalate crystals on potential inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345812"}
{"pmid": "4345813", "title": "Biochemical changes in intestinal mucosa after experimental small bowel by-pass in the rat.", "content": "Biochemical changes in intestinal mucosa after experimental small bowel by-pass in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345813"}
{"pmid": "4345814", "title": "Pressor response to angiotensin I and angiotensin II: the site of conversion of angiotensin I.", "content": "Pressor response to angiotensin I and angiotensin II: the site of conversion of angiotensin I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345814"}
{"pmid": "4345815", "title": "Protocollagen proline hydroxylase in the eye, cartilage and skin of chicken embryo.", "content": "Protocollagen proline hydroxylase in the eye, cartilage and skin of chicken embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345815"}
{"pmid": "4345816", "title": "Immunofluorescence for routine diagnosis of respiratory syncytial virus infection.", "content": "Immunofluorescence for routine diagnosis of respiratory syncytial virus infection. A comparison of immunofluorescent tests for the diagnosis of respiratory syncytial (RS) virus infections was carried out on 42 hospitalized cases of respiratory infection in childhood. Respiratory syncytial virus was detected in 22 (52%) cases, the most sensitive method of detection being by indirect immunofluorescence of Bristol HeLa tissue cultures inoculated with nasopharyngeal aspirates. The highest detection rate was in bronchiolitis cases (92%). Detection of antibody rises in paired sera, eight days apart, confirmed RS virus infection in 13 of 16 cases, the most sensitive test being detection of a specific rise in IgG antibody by indirect immunofluorescence. A serodiagnosis was made in all 10 non-bronchiolitis cases. Recommendations are made for the application ofimmunofluorescence to routine diagnosis of RS virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345816"}
{"pmid": "4345824", "title": "Electron spin resonance study of radicals produced by one-electron reduction of pyridines.", "content": "Electron spin resonance study of radicals produced by one-electron reduction of pyridines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345824"}
{"pmid": "4345829", "title": "Antitumor activity of polyinosinic-polycytidylic acid in combination with some biologically active compounds.", "content": "Antitumor activity of polyinosinic-polycytidylic acid in combination with some biologically active compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345829"}
{"pmid": "4345830", "title": "Differences in the primary structure of nucleolar and ribosomal high molecular weight RNA of the novikoff hepatoma and rat liver, and possible therapeutic implications.", "content": "Differences in the primary structure of nucleolar and ribosomal high molecular weight RNA of the novikoff hepatoma and rat liver, and possible therapeutic implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345830"}
{"pmid": "4345833", "title": "Nuclear magnetic resonance studies of rat serum lipoproteins.", "content": "Nuclear magnetic resonance studies of rat serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345833"}
{"pmid": "4345831", "title": "Relations between metabolic increase of plasma free fatty acids and the occurrence of arteriosclerotic thromboarteritis in rabbits.", "content": "Relations between metabolic increase of plasma free fatty acids and the occurrence of arteriosclerotic thromboarteritis in rabbits. Rabbits maintained for several weeks on a regimen of modest amounts of vitamin D and dietary cholesterol were placed in three groups in accordance with their response to repeated subcutaneous injections of nicotine in mineral oil. The group that had the greatest increase in plasma FFA following nicotine injections gradually developed, over a period of about 12 weeks, severe calcific atheroarteriosclerosis with peripheral thromboarteritis. Those that had a moderate increase in plasma FFA following nicotine injections developed calcific atheroarteriosclerosis but no thromboarteritis. Those that had the least increase in plasma FFA following nicotine injections developed no arterial lesions. Comparable or much greater increases in plasma FFA occurred in rabbits on the vitamin D-cholesterol regimen when adrenalin, ACTH or heparin was injected rather than nicotine. These animals did not develop calcific atheroarteriosclerotic thromboarteritis or any other lesions which could be correlated with the increased levels of plasma FFA. Inasmuch as nicotine, vitamin D or dietary cholesterol in the amounts used were innocuous when used alone, the interactions between the effects of at least these three factors need to be known in individual animals before the pathogenesis of the calcific atheroarteriosclerotic lesions with thrombosis can eventually be understood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345831"}
{"pmid": "4345834", "title": "A serologic survey of veterinarians for antibody to feline leukemia virus.", "content": "A serologic survey of veterinarians for antibody to feline leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345834"}
{"pmid": "4345835", "title": "Synopsis of vaccination procedures for dogs.", "content": "Synopsis of vaccination procedures for dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345835"}
{"pmid": "4345832", "title": "Plasma renin activity and blood pressure in 89 patients receiving maintenance haemodialysis therapy.", "content": "Plasma renin activity and blood pressure in 89 patients receiving maintenance haemodialysis therapy. Blood pressure, plasma renin activity, plasma sodium concentration, plasma potassium concentration, dietary sodium intake, and duration of dialysis have been measured under standard conditions in 89 patients on maintenance haemodialysis. No significant relation was found between plasma renin activity and blood pressure. Statistically significant correlations were found between plasma renin activity and plasma sodium concentration and between plasma renin activity and dietary sodium intake.Only one patient was found to have uncontrollable hypertension associated with a markedly raised plasma renin activity. Reasons are given for not performing bilateral nephrectomy in this patient. We believe the low incidence of uncontrollable hypertension and hyperreninaemia in our patients to be due to their slow introduction to haemodialysis, thus preventing violent swings in body weight, blood pressure, and renin secretion.Although plasma renin activity did fall with duration of dialysis, all 15 patients who have been on maintenance dialysis for longer than five years have normal levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345832"}
{"pmid": "4345836", "title": "Oxidative phosphorylation in mitochondria during embryonic development.", "content": "Oxidative phosphorylation in mitochondria during embryonic development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345836"}
{"pmid": "4345838", "title": "Changes in plasma insulin during ethanol-induced hypoglycemia.", "content": "Changes in plasma insulin during ethanol-induced hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345838"}
{"pmid": "4345839", "title": "Thiazide diuretics and calcium metabolism.", "content": "Thiazide diuretics and calcium metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345839"}
{"pmid": "4345842", "title": "The effect of initial body weight on the response of the rat to treatment with gonadotrophins.", "content": "The effect of initial body weight on the response of the rat to treatment with gonadotrophins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345842"}
{"pmid": "4345841", "title": "The effect of initial age on the response of the rat to treatment with gonadotrophins.", "content": "The effect of initial age on the response of the rat to treatment with gonadotrophins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345841"}
{"pmid": "4345843", "title": "Response of plasma aldosterone to angiotensin II, ACTH and potassium in man.", "content": "Response of plasma aldosterone to angiotensin II, ACTH and potassium in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345843"}
{"pmid": "4345844", "title": "Familial poly-endocrinopathy.", "content": "Familial poly-endocrinopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345844"}
{"pmid": "4345847", "title": "Respiration of homogenates and mitochondrial fractions of bovine dental pulp.", "content": "Respiration of homogenates and mitochondrial fractions of bovine dental pulp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345847"}
{"pmid": "4345850", "title": "Genetics of human-mouse somatic cell hybrids: linkage of human genes for isocitrate dehydrogenase and malate dehydrogenase.", "content": "Genetics of human-mouse somatic cell hybrids: linkage of human genes for isocitrate dehydrogenase and malate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345850"}
{"pmid": "4345851", "title": "Mitochondrial polymorphism. IV. Phospholipid composition of mitochondria of a wheat hybrid and its parents.", "content": "Mitochondrial polymorphism. IV. Phospholipid composition of mitochondria of a wheat hybrid and its parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345851"}
{"pmid": "4345852", "title": "Determination of adenosine 3':5'-cyclic monophosphate in cerebral tissues by saturation analysis. Assessment of a method using a binding protein from ox muscle.", "content": "Determination of adenosine 3':5'-cyclic monophosphate in cerebral tissues by saturation analysis. Assessment of a method using a binding protein from ox muscle. 1. The Gilman (1970) procedure for determining cyclic AMP (adenosine 3':5'-cyclic monophosphate) by saturation analysis gave erroneous results when applied to the analysis of extracts of whole brain or preparations of membrane fragments from brain. 2. The extracts contained a non-diffusible factor, which enhanced the binding of cyclic AMP by the muscle protein fraction. 3. Extracts also contained material which inhibited binding, but net inhibition of binding was only observed when relatively concentrated extracts were analysed. 4. The error introduced by the factors modifying binding could be eliminated by incorporation of unlabelled internal standards in the unknowns. The design adopted enables a statistical estimate to be made of the standard error of a single assay. 5. The modified assay was used to determine bound cyclic AMP and adenylate cyclase activity in cerebral membrane fragments. Five preparations of synaptic membrane fragments contained less than 3.5pmol of cyclic AMP/mg of protein; a microsomal fraction from rat contained 65pmol of cyclic AMP/mg of protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345852"}
{"pmid": "4345848", "title": "Cell biology of the mycoplasmas.", "content": "Cell biology of the mycoplasmas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345848"}
{"pmid": "4345855", "title": "The polyamine content in two slow-growing rat hepatomas.", "content": "The polyamine content in two slow-growing rat hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345855"}
{"pmid": "4345853", "title": "A heat-stable nicotinamide-adenine dinucleotide glycohydrolase from Pseudomonas putida KB1. Partial purification and some properties of the enzyme and an inhibitory protein.", "content": "A heat-stable nicotinamide-adenine dinucleotide glycohydrolase from Pseudomonas putida KB1. Partial purification and some properties of the enzyme and an inhibitory protein. A thermostable NAD(P)(+) glycohydrolase (EC 3.2.2.6) detected in cell-free extracts of Pseudomonas putida KB1 was purified to a single component on polyacrylamide-gel electrophoresis. A heat-labile inhibitor of the enzyme was also partially purified. Enzyme free of inhibitor is present in culture supernatants. After an ultrasonic treatment enzyme-inhibitor complex and excess of inhibitor are present in both the cell-debris and soluble fractions. The general properties of the enzyme and inhibitor are described. The molecular weights of enzyme, inhibitor and enzyme-inhibitor complex, determined by gel filtration are about 23500, 15000 and 35000 respectively. The binding of inhibitor and enzyme is inhibited by the presence of substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345853"}
{"pmid": "4345854", "title": "The structure of a glycerylphosphoryldiglucosyl diglyceride from the lipids of Acholeplasma laidlawii strain B.", "content": "The structure of a glycerylphosphoryldiglucosyl diglyceride from the lipids of Acholeplasma laidlawii strain B. 1. The phosphatidylglucose structure proposed previously (Smith & Henrikson, 1965) for the glucose-containing phospholipid from Acholeplasma laidlawii is incorrect. 2. The structure now proposed is 3-(sn-glycerol-3-phosphoryl-6'-[O-alpha-d-glucopyranosyl-(1-->2)-O-alpha-d-glucopyranosyl])- sn-1,2-diglyceride, a new type of bacterial lipid. 3. Deacylation of the lipid gave a single water-soluble phosphate ester which could be distinguished on chromatography from synthetic samples of glucosylphosphorylglycerols. 4. Hydrolysis of the lipid with alkali gave a mixture of fatty acids, glycerol 2-phosphate, sn-glycerol 3-phosphate and O-alpha-d-glucopyranosyl-(1-->2)-O-alpha- d-glucopyranosyl-(1-->1)-d-glycerol. 5. The lipid was unaffected on incubation with phospholipases A, C and D. 6. Diglucosyl diglyceride was isolated after treatment of the lipid with 60% HF, establishing the location of the fatty acid residues. 7. Periodate oxidation studies showed that the sn-glycerol 3-phosphate was esterified to the 6-hydroxyl group of one of the glucose residues in diglucosyl diglyceride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345854"}
{"pmid": "4345856", "title": "The chemistry of the collagen cross-links. A convenient synthesis of the reduction products of several collagen cross-links and cross-link precursors.", "content": "The chemistry of the collagen cross-links. A convenient synthesis of the reduction products of several collagen cross-links and cross-link precursors. New synthetic routes to the reduction products of several collagen cross-links and cross-link precursors are described. By the use of these routes hydroxynorleucine, 5,6-dihydroxynorleucine, hydroxylysinonorleucine and hydroxylysinohydroxynorleucine can be synthesized via one common synthetic intermediate. The synthetic routes provide a convenient source of these unusual amino acids, as well as confirming the structure of hydroxylysinohydroxynorleucine and the other lysine-derived residues found in borohydride-reduced collagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345856"}
{"pmid": "4345849", "title": "Molecular structure of bacterial plasmids.", "content": "Molecular structure of bacterial plasmids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345849"}
{"pmid": "4345857", "title": "Effect of oxidative phosphorylation inhibitors on cyclic adenosine monophosphate synthesis in rat adipose tissue.", "content": "Effect of oxidative phosphorylation inhibitors on cyclic adenosine monophosphate synthesis in rat adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345857"}
{"pmid": "4345858", "title": "Biochemical lesion in rat liver mitochondria induced by hexachlorophene.", "content": "Biochemical lesion in rat liver mitochondria induced by hexachlorophene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345858"}
{"pmid": "4345859", "title": "1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic 3',5'-nucleotide phosphodiesterases.", "content": "1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic 3',5'-nucleotide phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345859"}
{"pmid": "4345861", "title": "Metabolic action of urethan on protein synthesis and drug oxidation in normal and regenerating liver.", "content": "Metabolic action of urethan on protein synthesis and drug oxidation in normal and regenerating liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345861"}
{"pmid": "4345860", "title": "Control of prostaglandin biosynthesis in rat brain homogenates by adenine nucleotides.", "content": "Control of prostaglandin biosynthesis in rat brain homogenates by adenine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345860"}
{"pmid": "4345862", "title": "Cyclic 3',5'-adenosine monophosphate response in the rabbit lung--adult properties and development.", "content": "Cyclic 3',5'-adenosine monophosphate response in the rabbit lung--adult properties and development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345862"}
{"pmid": "4345864", "title": "NaF inhibition of phosphorylation and dephosphorylation involved in  -methyl-D glucoside transport in E. coli K 12. A pH dependant phenomenon sensitive to uncoupling agents.", "content": "NaF inhibition of phosphorylation and dephosphorylation involved in  -methyl-D glucoside transport in E. coli K 12. A pH dependant phenomenon sensitive to uncoupling agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345864"}
{"pmid": "4345866", "title": "On the determination of the molecular weight of lactate dehydrogenase by gel filtration on Sephadex G-200.", "content": "On the determination of the molecular weight of lactate dehydrogenase by gel filtration on Sephadex G-200.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345866"}
{"pmid": "4345867", "title": "Inheritance of syndactyly.", "content": "Inheritance of syndactyly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345867"}
{"pmid": "4345869", "title": "Follow-up of hydatidiform mole by radioimmunoassay of human chorionic gonadotrophin.", "content": "Follow-up of hydatidiform mole by radioimmunoassay of human chorionic gonadotrophin. An improved method for the follow-up of patients delivered of a hydatidiform mole using radioimmunoassay of human chorionic gonadotrophin is employed to ensure adequate sensitivity. Four illustrative case histories are described. Their HCG findings are presented to show that this is the principal basis on which decisions should be made.There are three aspects to the work of the laboratory. The technical work of the assay, the clerical effort of patient follow-up, and the clinical interpretation of results. The laboratory keeps a close check on follow-up (one of its most important functions) and receives specimens direct from patients. Overall control of all three aspects is by a clinician. It has been found useful to organize a special clinic for these patients to be seen. In this region it has been possible for this to be run by the same clinician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345869"}
{"pmid": "4345868", "title": "Changes of blood pressure, renin, and angiotensin after bilateral nephrectomy in patients with chronic renal failure.", "content": "Changes of blood pressure, renin, and angiotensin after bilateral nephrectomy in patients with chronic renal failure. Circulating levels of renin, angiotensin I, and angiotensin II were increased in six patients with chronic renal failure and hypertension uncontrolled by dialysis and hypotensive drugs. Lower and often normal levels were found in 10 patients whose blood pressure was controlled by dialysis treatment. For a variety of reasons all patients were subjected to bilateral nephrectomy. The logarithm of the decrease in plasma concentrations of renin and angiotensin II was significantly related to the fall of blood pressure after operation. Plasma renin concentration correlated significantly with blood angiotensin I concentration and with plasma angiotensin II in samples taken before and after nephrectomy. Renin, angiotensin I, and angiotensin II were measurable in samples of blood taken 48 hours or more after the operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345868"}
{"pmid": "4345870", "title": "Kinetic measurements with monocarboxylic acids as substrates and effectors of glutamate dehydrogenase.", "content": "Kinetic measurements with monocarboxylic acids as substrates and effectors of glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345870"}
{"pmid": "4345871", "title": "Interaction of hydrogen peroxide with superoxide dismutase from erythrocytes.", "content": "Interaction of hydrogen peroxide with superoxide dismutase from erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345871"}
{"pmid": "4345872", "title": "Myeloproliferative disease in a turtle.", "content": "Myeloproliferative disease in a turtle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345872"}
{"pmid": "4345873", "title": "Morbidity in post-myelogram patients--a survey of 100 patients.", "content": "Morbidity in post-myelogram patients--a survey of 100 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345873"}
{"pmid": "4345874", "title": "Congenital syphilitic deafness.", "content": "Congenital syphilitic deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345874"}
{"pmid": "4345876", "title": "Adolescent anorexia nervosa: the patient; an approach.", "content": "Adolescent anorexia nervosa: the patient; an approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345876"}
{"pmid": "4345884", "title": "Rehabilitation and health visitor follow-up.", "content": "Rehabilitation and health visitor follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345884"}
{"pmid": "4345875", "title": "Instant pudding.", "content": "Instant pudding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345875"}
{"pmid": "4345877", "title": "Trends in psychiatric care in Europe.", "content": "Trends in psychiatric care in Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345877"}
{"pmid": "4345880", "title": "Nursing management of feelings, thoughts and behavior.", "content": "Nursing management of feelings, thoughts and behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345880"}
{"pmid": "4345879", "title": "Hydrotherapy--is it all washed up?", "content": "Hydrotherapy--is it all washed up?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345879"}
{"pmid": "4345878", "title": "The financial plight of the elderly.", "content": "The financial plight of the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345878"}
{"pmid": "4345890", "title": "Malignant nonchromaffin paraganglioma.", "content": "Malignant nonchromaffin paraganglioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345890"}
{"pmid": "4345891", "title": "Electron paramagnetic resonance studies on the selenium-replaced derivatives of adrenodoxin: the presence of the one selenium-one sulfur compound.", "content": "Electron paramagnetic resonance studies on the selenium-replaced derivatives of adrenodoxin: the presence of the one selenium-one sulfur compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345891"}
{"pmid": "4345892", "title": "Hormone-treated CHO cells exit the cell cycle in the G2 phase.", "content": "Hormone-treated CHO cells exit the cell cycle in the G2 phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345892"}
{"pmid": "4345893", "title": "Cycl AMP in Gl-arrested BHK21 cells infected with adenovirus type 12.", "content": "Cycl AMP in Gl-arrested BHK21 cells infected with adenovirus type 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345893"}
{"pmid": "4345894", "title": "The effect of hydration of lecithin-water lamellar phases: a comparative study of solute diffusion and ESR spectroscopic measurements.", "content": "The effect of hydration of lecithin-water lamellar phases: a comparative study of solute diffusion and ESR spectroscopic measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345894"}
{"pmid": "4345895", "title": "Isolation and preliminary characterization of corticosterone-receptor complexes in mouse placental tissue.", "content": "Isolation and preliminary characterization of corticosterone-receptor complexes in mouse placental tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345895"}
{"pmid": "4345896", "title": "Effect of glycolysis inhibitors on cyclic AMP synthesis in rat adipose tissue.", "content": "Effect of glycolysis inhibitors on cyclic AMP synthesis in rat adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345896"}
{"pmid": "4345897", "title": "Partial purification and characterization of a renin-like enzyme from rat submandibular gland.", "content": "Partial purification and characterization of a renin-like enzyme from rat submandibular gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345897"}
{"pmid": "4345899", "title": "Effects of acute hypocapnia and hypercapnia on neuromuscular transmission and on monosynaptic spinal reflex in wakeful man.", "content": "Effects of acute hypocapnia and hypercapnia on neuromuscular transmission and on monosynaptic spinal reflex in wakeful man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345899"}
{"pmid": "4345900", "title": "The \"wheat-stubble sarcoid granuloma\": a new epithelioid granuloma of the skin.", "content": "The \"wheat-stubble sarcoid granuloma\": a new epithelioid granuloma of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345900"}
{"pmid": "4345901", "title": "Retrobulbar granular cell myoblastoma.", "content": "Retrobulbar granular cell myoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345901"}
{"pmid": "4345902", "title": "Results of early mobilization and discharge after myocardial infarction.", "content": "Results of early mobilization and discharge after myocardial infarction. A total of 342 patients with acute myocardial infarction who were admitted to a coronary care unit are reviewed to assess the results of early mobilization and discharge. The mean duration of admission was 8.4 days and 89% of the survivors were discharged from hospital by the tenth day. The inpatient mortality was 15.5%. An additional 6.7% died during the six weeks' follow-up period, giving a total mortality of 22.2%. Altogether, 7.6% of patients were readmitted. Venous thromboembolic phenomena occurred in 3.5% during the inpatient period. Of patients who were eligible 62% were back at work five months after their myocardial infarction. We think the results justify a short hospital admission period for acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345902"}
{"pmid": "4345904", "title": "Triglyceride storage disease: a disorder of lipolysis in adipose tissue in two patients.", "content": "Triglyceride storage disease: a disorder of lipolysis in adipose tissue in two patients. An obese patient was studied whose adipose tissue showed a significant reduction in release of glycerol (P < 0.05) when stimulated by isoprenaline despite normal rises in tissue levels of cyclic-AMP. However, lipolysis was stimulated by a fast of 14 days as judged by weight loss and a rise in plasma fatty acids from 0.4 to 1.2 mM. The defect in this patient may be familial since her obese daughter also showed diminished release of glycerol from adipose tissue on three occasions when stimulated by isoprenaline, despite normal rises in levels of cyclic-AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345904"}
{"pmid": "4345903", "title": "Immunological studies in Ugandan patients with hepatocellular carcinoma.", "content": "Immunological studies in Ugandan patients with hepatocellular carcinoma. Immunological studies were performed on Ugandan patients with hepatocellular carcinoma to test the hypothesis that the high rate of persistence of hepatitis-associated antigen in these patients is the result of defects in host immune response. The responses to 1-chloro-2,4-dinitrobenzene sensitization and to a battery of recall skin test antigens were normal, as was the humoral antibody response to tularaemia antigen. Neither hypogammaglobulinaemia nor specific immunoglobulin deficiencies were found. Thus it appears unlikely that generalized defects in host immune responses can account for the high incidence of persistent hepatitis B virus infection found in Ugandan patients with hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345903"}
{"pmid": "4345905", "title": "Zollinger-Ellison syndrome revisited.", "content": "Zollinger-Ellison syndrome revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345905"}
{"pmid": "4345906", "title": "Where to die.", "content": "Where to die.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345906"}
{"pmid": "4345907", "title": "Monkeypox.", "content": "Monkeypox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345907"}
{"pmid": "4345908", "title": "Four recurring themes.", "content": "Four recurring themes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345908"}
{"pmid": "4345909", "title": "Ocular dyskinesia in cerebellar disease. Evidence for the similarity of opsoclonus, ocular dysmetria and flutter-like oscillations.", "content": "Ocular dyskinesia in cerebellar disease. Evidence for the similarity of opsoclonus, ocular dysmetria and flutter-like oscillations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345909"}
{"pmid": "4345910", "title": "Hereditary neuropathy with liability to pressure palsies. Electrophysiological and histopathological aspects.", "content": "Hereditary neuropathy with liability to pressure palsies. Electrophysiological and histopathological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345910"}
{"pmid": "4345911", "title": "Purification and properties of rat liver nuclear protein kinases.", "content": "Purification and properties of rat liver nuclear protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345911"}
{"pmid": "4345912", "title": "Lipid composition and synthesis in the muscles of normal and dystrophic chickens.", "content": "Lipid composition and synthesis in the muscles of normal and dystrophic chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345912"}
{"pmid": "4345913", "title": "The amino acid sequence of cytochrome c-553 from the Chrysophycean alga Monochrysis lutheri.", "content": "The amino acid sequence of cytochrome c-553 from the Chrysophycean alga Monochrysis lutheri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345913"}
{"pmid": "4345914", "title": "Purification of isoenzyme and coenzymes for kinetic study of horse liver alcohol dehydrogenase.", "content": "Purification of isoenzyme and coenzymes for kinetic study of horse liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345914"}
{"pmid": "4345915", "title": "Kinetic mechanism for the major isoenzyme of horse liver alcohol dehydrogenase.", "content": "Kinetic mechanism for the major isoenzyme of horse liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345915"}
{"pmid": "4345916", "title": "Adenylate cyclase and insulin action. Effect of insulin, nonsuppressible insulin-like material, and diabetes on adenylate-cyclase activity in mouse liver.", "content": "Adenylate cyclase and insulin action. Effect of insulin, nonsuppressible insulin-like material, and diabetes on adenylate-cyclase activity in mouse liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345916"}
{"pmid": "4345917", "title": "Bicuculline and thalamic inhibition.", "content": "Bicuculline and thalamic inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345917"}
{"pmid": "4345918", "title": "Secondary antibody-forming potential of aged mice, with special reference to the influence of adjuvant on priming.", "content": "Secondary antibody-forming potential of aged mice, with special reference to the influence of adjuvant on priming.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345918"}
{"pmid": "4345919", "title": "The activation of chloride transport by epinephrine and Db cyclic-AMP in the cornea of the rabbit.", "content": "The activation of chloride transport by epinephrine and Db cyclic-AMP in the cornea of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345919"}
{"pmid": "4345921", "title": "Survival of Arthrobacter crystallopoietes during prolonged periods of extreme desiccation.", "content": "Survival of Arthrobacter crystallopoietes during prolonged periods of extreme desiccation. Cells of Arthrobacter crystallopoietes mixed in sand and air-dried have survived for up to 6 months after an initial period in which approximately half the cells lost their viability. Comparative survival curves have been obtained from inoculated sands maintained under CaSO(4) or P(2)O(5). Selections for more desiccation-resistant progeny capable of surviving the initial period were unsuccessful. Both the coccoid and rod-shaped forms are equally resistant to several months of desiccation. Desiccated spherical cells converted 0.0005% of their cell carbon to carbon dioxide per hr, which corresponds to a half-life for self-consumption of approximately 12 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345921"}
{"pmid": "4345920", "title": "Ultraviolet-sensitive mutator strain of Escherichia coli K-12.", "content": "Ultraviolet-sensitive mutator strain of Escherichia coli K-12. An ultraviolet (UV)-sensitive mutator gene, mutU, was identified in Escherichia coli K-12. The mutation mutU4 is very close to uvrD, between metE and ilv, on the E. coli chromosome. It was recessive as a mutator and as a UV-sensitive mutation. The frequency of reversion of trpA46 on an F episome was increased by mutU4 on the chromosome. The mutator gene did not increase mutation frequencies in virulent phages or in lytically grown phage lambda. The mutU4 mutation predominantly induced transitional base changes. Mutator strains were normal for recombination and host-cell reactivation of UV-irradiated phage T1. They were normally resistant to methyl methanesulfonate and were slightly more sensitive to gamma irradiation than Mut(+) strains. UV irradiation induced mutations in a mutU4 strain, and phage lambda was UV-inducible. Double mutants containing mutU4 and recA, B, or C were extremely sensitive to UV irradiation; a mutU4 uvrA6 double mutant was only slightly more sensitive than a uvrA6 strain. The mutU4 uvrA6 and mutU4 recA, B, or C double mutants had mutation rates similar to that of a mutU4 strain. Two UV-sensitive mutators, mut-9 and mut-10, isolated by Liberfarb and Bryson in E. coli B/UV, were found to be co-transducible with ilv in the same general region as mutU4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345920"}
{"pmid": "4345923", "title": "Acute renal failure followed by protracted, slowly resolving chronic uremia.", "content": "Acute renal failure followed by protracted, slowly resolving chronic uremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345923"}
{"pmid": "4345922", "title": "Specialized subregions of the bifunctional hisB gene of Salmonella typhimurium.", "content": "Specialized subregions of the bifunctional hisB gene of Salmonella typhimurium. Forty-three hisB mutants of Salmonella typhimurium have been screened to determine the molecular size of the resulting histidinol phosphate phosphatase activity, one of the activities of a bifunctional enzyme produced by this gene which also controls imidazole glycerol phosphate dehydrase activity. Mutation in hisB can lead to the loss of both phosphatase and dehydrase activities, or only of dehydrase activity. Through the use of nonsense mutants lacking dehydrase activity, a distinct point of transition was detected near the middle of hisB at which a dramatic change occurs in the size of the phosphatase enzyme that is synthesized. A missense mutant with a lesion in this region has a high-molecular-weight enzyme which is eluted in the void volume of a Sephadex G-200 column. The enzyme from nonsense mutants near the transition point have molecular weights near 40,000. Even though the buffer conditions are designed to favor the stabilization of the high-molecular-weight form, some mutants have both high- and low-molecular-weight forms. The polypeptide chain specified by the operator proximal part of hisB is sufficient to allow the expression of phosphatase activity. The synthesis of substantially less than the complete product of hisB resulted in association into a form similar to the native enzyme which was found in the void volume of a Sephadex G-200 column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345922"}
{"pmid": "4345924", "title": "Electron-microscope observations on the formation of the cytoplasmic lamellar inclusion bodies in murine pulmonary tumours induced in vitro.", "content": "Electron-microscope observations on the formation of the cytoplasmic lamellar inclusion bodies in murine pulmonary tumours induced in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345924"}
{"pmid": "4345925", "title": "Membrane depolarization, cyclic AMP and glycerol release by brown fat in vitro.", "content": "Membrane depolarization, cyclic AMP and glycerol release by brown fat in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345925"}
{"pmid": "4345926", "title": "Inhibition of post-ganglionic motor transmission in vas deferens by indirectly acting sympathomimetic drugs.", "content": "Inhibition of post-ganglionic motor transmission in vas deferens by indirectly acting sympathomimetic drugs. 1. Using field stimulation with short trains of pulses (< 10 per train), the post-ganglionic motor transmission in the mammalian vas deferens has been further analysed pharmacologically.2. In preparations taken from guinea-pigs, rats and rabbits the effects of the indirectly sympathomimetic drugs, tyramine and cocaine, could be explained entirely on the basis of the actions of released, endogenous noradrenaline.3. Tyramine produced a contraction in vasa taken from normal rats but not from normal guinea-pigs. The tyramine contraction was due to release of endogenous noradrenaline because it was not seen in preparations taken from reserpinized rats and because it was abolished in normal vasa by phenoxybenzamine or phentolamine, thus denying the supposed inaccessibility, to alpha-blockers, of the motor alpha-adrenoceptors activated by endogenous noradrenaline.4. Phenoxybenzamine or phentolamine failed to block post-ganglionic motor transmission in rat and in guinea-pig vasa.5. Tyramine strongly inhibited motor transmission in vasa taken from normal but not from reserpinized guinea-pigs.6. Tyramine produced inhibition of motor transmission in phenoxybenzamine-treated preparations taken from normal but not from reserpinized rats.7. Cocaine inhibited motor transmission in guinea-pig and in rat vasa. This effect was not due to a local anaesthetic or to a smooth-muscle depressant action because it did not occur in preparations taken from reserpinized animals.8. The inhibitory effect of tyramine or cocaine was not abolished by beta-adrenoceptor blockade with propranolol.9. Whereas reserpinization abolished the tyramine- and cocaine-inhibitions, it did not affect the inhibitory actions of noradrenaline or of PGE(2).10. Indomethacin and sodium meclofenamate, which suppress prostaglandin synthesis, did not affect the twitch-inhibiting actions of noradrenaline, tyramine or cocaine.11. These results provide further support for the conclusion that post-ganglionic motor transmission to the vas deferens is non-adrenergic in these species and assign to endogenously released noradrenaline an inhibitory role upon motor transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345926"}
{"pmid": "4345927", "title": "Transmitter release from insect excitatory motor nerve terminals.", "content": "Transmitter release from insect excitatory motor nerve terminals. 1. Intracellular and extracellular electrodes were used to study spontaneous and impulse-linked release of transmitter at locust retractor unguis nerve-muscle synapses.2. At most extracellular recording sites the amplitude distributions of the excitatory post-synaptic potentials (e.p.s.p.s) were apparently non-Poisson. However, interpretation of these amplitude distributions was complicated by the effect on the extracellular recordings of the complex structural organization of the retractor unguis nerve terminal with its spatially distinct transmitter release sites extending over distances of 15-30 mum.3. The spontaneous miniature excitatory post-synaptic potentials (min e.p.s.p.s) did not occur at random intervals, bursts of min e.p.s.p.s being frequently recorded. As a result the spontaneous release of transmitter rarely approximated a Poisson process.4. For a period of at least 390 msec following a conditioning nerve impulse a test e.p.s.p. was facilitated and the probability of spontaneous transmitter release was enhanced. A large primary phase of facilitation of impulse-linked and spontaneous release was invariably followed by one or more secondary phases of smaller magnitude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345927"}
{"pmid": "4345928", "title": "Historical vignette. Calomel and the American medical sects during the nineteenth century.", "content": "Historical vignette. Calomel and the American medical sects during the nineteenth century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345928"}
{"pmid": "4345929", "title": "Experience with radioisotope scanning of the pancreas.", "content": "Experience with radioisotope scanning of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345929"}
{"pmid": "4345930", "title": "Properties of a temperature sensitive plasmid in Citrobacter freundii.", "content": "Properties of a temperature sensitive plasmid in Citrobacter freundii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345930"}
{"pmid": "4345934", "title": "Symptomatic hypoglycemia in adults: a protocol for clinical and laboratory evaluation.", "content": "Symptomatic hypoglycemia in adults: a protocol for clinical and laboratory evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345934"}
{"pmid": "4345935", "title": "Plasmodial ultrastructure of the myxomycete Physarum polycephalum.", "content": "Plasmodial ultrastructure of the myxomycete Physarum polycephalum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345935"}
{"pmid": "4345936", "title": "Fine structural studies on digestion of bacterial species in the rumen ciliate, Entodinium caudatum.", "content": "Fine structural studies on digestion of bacterial species in the rumen ciliate, Entodinium caudatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345936"}
{"pmid": "4345937", "title": "Morphology and behaviour of cultured aëdes aegypti mosquito cells.", "content": "Morphology and behaviour of cultured aëdes aegypti mosquito cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345937"}
{"pmid": "4345940", "title": "The fine structure of the human oocyte. I. Oval granulo-vesicular bodies.", "content": "The fine structure of the human oocyte. I. Oval granulo-vesicular bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345940"}
{"pmid": "4345941", "title": "Immunocytological observations on the localization of ACTH in the hypophysis of the dog.", "content": "Immunocytological observations on the localization of ACTH in the hypophysis of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345941"}
{"pmid": "4345942", "title": "Structural studies on the synapsis of the toad, Bufo arenarum, Hensel. I. Special forms of dendro-dendritic, dendro-somatic and axo-somatic contacts.", "content": "Structural studies on the synapsis of the toad, Bufo arenarum, Hensel. I. Special forms of dendro-dendritic, dendro-somatic and axo-somatic contacts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345942"}
{"pmid": "4345944", "title": "Mononucleosis with heterophil antibodies and EB virus infection. Acquisition by an elderly patient in hospital.", "content": "Mononucleosis with heterophil antibodies and EB virus infection. Acquisition by an elderly patient in hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345944"}
{"pmid": "4345943", "title": "Serial lipid and lipoprotein responses to the American Heart Association fat-controlled diet.", "content": "Serial lipid and lipoprotein responses to the American Heart Association fat-controlled diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345943"}
{"pmid": "4345945", "title": "Recurrent lacrimal gland tumor.", "content": "Recurrent lacrimal gland tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345945"}
{"pmid": "4345946", "title": "Electron microscope study of the morphogenesis of a new canine herpesvirus in dog kidney cells.", "content": "Electron microscope study of the morphogenesis of a new canine herpesvirus in dog kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345946"}
{"pmid": "4345947", "title": "Induction of DNase activity in monkey cell cultures infected by simian virus 40.", "content": "Induction of DNase activity in monkey cell cultures infected by simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345947"}
{"pmid": "4345948", "title": "Effect of panosialin on myxoviruses.", "content": "Effect of panosialin on myxoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345948"}
{"pmid": "4345949", "title": "Some aspects of the morphogenesis of myxoma virus in vivo.", "content": "Some aspects of the morphogenesis of myxoma virus in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345949"}
{"pmid": "4345950", "title": "Viral replication in mouse macrophages.", "content": "Viral replication in mouse macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345950"}
{"pmid": "4345952", "title": "Role of spleen in production of virus induced interferon in rabbits. Brief report.", "content": "Role of spleen in production of virus induced interferon in rabbits. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345952"}
{"pmid": "4345951", "title": "Comparison of SV 40 RNA from infected cells and SV 40 cRNA made by RNA polymerase from Escherichia coli.", "content": "Comparison of SV 40 RNA from infected cells and SV 40 cRNA made by RNA polymerase from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345951"}
{"pmid": "4345953", "title": "Oestrogen metabolism in cultured human breast tumours.", "content": "Oestrogen metabolism in cultured human breast tumours. The interconversion of tritium labelled oestrone and oestradiol-17β has been investigated in human breast tumours maintained in organ culture for 3 days. Benign tumours were significantly different from scirrhous carcinomata both in the concentration of radioactivity taken up by the tissue and in the ratios of oestradiol-17β/oestrone achieved. The fact that malignant tumours were able to convert oestrone to oestradiol-17β is of interest in view of the relatively high plasma levels of oestrone in post-menopausal women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345953"}
{"pmid": "4345955", "title": "Why women form their own professional organizations.", "content": "Why women form their own professional organizations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345955"}
{"pmid": "4345956", "title": "M.D.? Mrs.?--PM&R.", "content": "M.D.? Mrs.?--PM&R.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345956"}
{"pmid": "4345958", "title": "Rehabilitation in modern medicine.", "content": "Rehabilitation in modern medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345958"}
{"pmid": "4345957", "title": "The incidence and curability of cancer of the uterine cervix in El Paso County 1944-1967.", "content": "The incidence and curability of cancer of the uterine cervix in El Paso County 1944-1967.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345957"}
{"pmid": "4345959", "title": "Characteristics of fast feedback control of corticotrophin release by corticosteroids.", "content": "Characteristics of fast feedback control of corticotrophin release by corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345959"}
{"pmid": "4345960", "title": "A chemostat study of the effect of fixed nitrogen sources on nitrogen fixation, membranes and free amino acids in Azotobacter chroococcum.", "content": "A chemostat study of the effect of fixed nitrogen sources on nitrogen fixation, membranes and free amino acids in Azotobacter chroococcum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345960"}
{"pmid": "4345961", "title": "The polar lipids of some species of Nocardia.", "content": "The polar lipids of some species of Nocardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345961"}
{"pmid": "4345962", "title": "Chemodectoma of larynx.", "content": "Chemodectoma of larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345962"}
{"pmid": "4345963", "title": "The ultrastructure of chemodectoma of the larynx.", "content": "The ultrastructure of chemodectoma of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345963"}
{"pmid": "4345964", "title": "[Radioimmunoassay of alpha-fetoprotein in primary and secondary cancer of the liver].", "content": "[Radioimmunoassay of alpha-fetoprotein in primary and secondary cancer of the liver].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345964"}
{"pmid": "4345966", "title": "Chronic poliovirus infection of cocultivated monkey cells harboring the Mason-Pfizer monkey virus.", "content": "Chronic poliovirus infection of cocultivated monkey cells harboring the Mason-Pfizer monkey virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345966"}
{"pmid": "4345967", "title": "Cell-mediated tumor immunity measured in vitro and in vivo with soluble tumor-specific antigens.", "content": "Cell-mediated tumor immunity measured in vitro and in vivo with soluble tumor-specific antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345967"}
{"pmid": "4345968", "title": "Mammary gland tumors in substrains C57BL-M and C57BL-He mice.", "content": "Mammary gland tumors in substrains C57BL-M and C57BL-He mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345968"}
{"pmid": "4345970", "title": "Carcinoembryonic antigen: synthesis by a continuous line of adenocarcinoma cells.", "content": "Carcinoembryonic antigen: synthesis by a continuous line of adenocarcinoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345970"}
{"pmid": "4345971", "title": "Growth of Rous sarcomas in bursectomized chickens.", "content": "Growth of Rous sarcomas in bursectomized chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345971"}
{"pmid": "4345969", "title": "An anemia-inducing virus derived from tumors caused by murine sarcoma virus--Moloney.", "content": "An anemia-inducing virus derived from tumors caused by murine sarcoma virus--Moloney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345969"}
{"pmid": "4345972", "title": "Differential enhancement of R-type virus particles in polyoma-transformed BHK-21 cells by dimethyl sulfoxide.", "content": "Differential enhancement of R-type virus particles in polyoma-transformed BHK-21 cells by dimethyl sulfoxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345972"}
{"pmid": "4345973", "title": "Spontaneous disseminated squirrel fibroma.", "content": "Spontaneous disseminated squirrel fibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345973"}
{"pmid": "4345974", "title": "Siegler R:Proposed classification of the murine leukemia-sarcoma viruses.", "content": "Siegler R:Proposed classification of the murine leukemia-sarcoma viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345974"}
{"pmid": "4345975", "title": "The mechanism of enhanced clearance of colloidal carbon from the blood of rabbits stimulated with a tubercle bacillary lipid.", "content": "The mechanism of enhanced clearance of colloidal carbon from the blood of rabbits stimulated with a tubercle bacillary lipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345975"}
{"pmid": "4345977", "title": "Bovine respiratory syncytial virus. Studies on an outbreak in Japan, 1968-1969.", "content": "Bovine respiratory syncytial virus. Studies on an outbreak in Japan, 1968-1969.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345977"}
{"pmid": "4345978", "title": "Distribution of antibodies in dogs against adenosatellite viruses.", "content": "Distribution of antibodies in dogs against adenosatellite viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345978"}
{"pmid": "4345979", "title": "Distribution of complement-requiring neutralizing antibody against herpes simplex virus in human population.", "content": "Distribution of complement-requiring neutralizing antibody against herpes simplex virus in human population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345979"}
{"pmid": "4345980", "title": "Sphingolipids of the fungi Phycomycetes blakesleeanus and Fusarium lini.", "content": "Sphingolipids of the fungi Phycomycetes blakesleeanus and Fusarium lini.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345980"}
{"pmid": "4345981", "title": "Effects of parathion on lipolysis in isolated rat adipose tissue cells.", "content": "Effects of parathion on lipolysis in isolated rat adipose tissue cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345981"}
{"pmid": "4345984", "title": "Benign and malignant mixed tumours of the lung.", "content": "Benign and malignant mixed tumours of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345984"}
{"pmid": "4345985", "title": "Elephantiasis and silicates.", "content": "Elephantiasis and silicates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345985"}
{"pmid": "4345986", "title": "Ultrastructural changes in the rat liver following protracted treatment with pregnenolone-16 -carbonitrile and digitoxin.", "content": "Ultrastructural changes in the rat liver following protracted treatment with pregnenolone-16 -carbonitrile and digitoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345986"}
{"pmid": "4345987", "title": "Nucleoside triphosphatase activity in induced mammary tumours in rats.", "content": "Nucleoside triphosphatase activity in induced mammary tumours in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345987"}
{"pmid": "4345988", "title": "Open tubular heterogeneous enzyme reactors: preparation and kinetic behavior.", "content": "Open tubular heterogeneous enzyme reactors: preparation and kinetic behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345988"}
{"pmid": "4345989", "title": "A survey of the viruses of farm animals in Northern Ireland.", "content": "A survey of the viruses of farm animals in Northern Ireland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345989"}
{"pmid": "4345990", "title": "An abnormality of adrenaline, phentolamine stimulated lipolysis in adipose tissue from obese, maturity-onset diabetics.", "content": "An abnormality of adrenaline, phentolamine stimulated lipolysis in adipose tissue from obese, maturity-onset diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345990"}
{"pmid": "4345991", "title": "The mechanism of insulin secretion after oral glucose administration. 3. Investigations on the mechanism of a reflectoric insulin mobilization after oral stimulation.", "content": "The mechanism of insulin secretion after oral glucose administration. 3. Investigations on the mechanism of a reflectoric insulin mobilization after oral stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345991"}
{"pmid": "4345994", "title": "Retinal fine structure after long term anaesthesia.", "content": "Retinal fine structure after long term anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345994"}
{"pmid": "4345993", "title": "The concentration of lactic acid in rabbit lenses of various ages.", "content": "The concentration of lactic acid in rabbit lenses of various ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345993"}
{"pmid": "4345997", "title": "The effect of cyclic AMP on the production of single-strand breaks in DNA of x-irradiated E. coli B-r.", "content": "The effect of cyclic AMP on the production of single-strand breaks in DNA of x-irradiated E. coli B-r.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345997"}
{"pmid": "4345996", "title": "8-Azaguanine resistance in mammalian cells. I. Hypoxanthine-guanine phosphoribosyltransferase.", "content": "8-Azaguanine resistance in mammalian cells. I. Hypoxanthine-guanine phosphoribosyltransferase. Chinese hamster cells were treated with ethyl methanesulfonate or N-methyl-N'-nitro-N-nitrosoguanidine, and mutants resistant to 8-azaguanine were selected and characterized. Hypoxanthine-guanine phosphoribosyltransferase activity of sixteen mutants is extremely negative, making them suitable for reversion to HGPRTase(+). Ten of the extremely negative mutants revert at a frequency higher than 10(-7) suggesting their point mutational character. The remaining mutants have demonstrable HGPRTase activity and are not useful for reversion analysis. Five of these mutants have < 2% HGPRTase and are presumably also HGPRTase point mutants. The remaining 14 mutants utilize exogenous hypoxanthine for nucleic acid synthesis poorly, and possess 20-150% of wild-type HGPRTase activity in in vitro. Their mechanism of 8-azaguanine resistance is not yet defined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345996"}
{"pmid": "4345998", "title": "Ultrastructural examination of ageing and radiation-induced life-span shortening in adult Drosophila melanogaster.", "content": "Ultrastructural examination of ageing and radiation-induced life-span shortening in adult Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345998"}
{"pmid": "4345999", "title": "Comparative effects of electron and neutron irradiation on the release of enzymes from isolated rat-spleen lysosomes.", "content": "Comparative effects of electron and neutron irradiation on the release of enzymes from isolated rat-spleen lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4345999"}
{"pmid": "4346005", "title": "The interaction of serum and arterial lipoproteins with elastin of the arterial intima and its role in the lipid accumulation in atherosclerotic plaques.", "content": "The interaction of serum and arterial lipoproteins with elastin of the arterial intima and its role in the lipid accumulation in atherosclerotic plaques. Arterial elastin appears to be a proteinlipid complex with the lipid component being bound to elastin peptide groups. In atherosclerotic lesions the lipid content of elastin increases progressively with increasing severity of atherosclerosis. The increases in the lipid content of plaque elastin are mainly due to large increases in cholesterol with about 80% of the cholesterol being cholesterol ester. This deposition of cholesterol in elastin accounts for a substantial part of the total cholesterol accumulation in atherosclerotic lesions of all stages. The present in vitro study suggests that the mechanism involved in the deposition of lipids in arterial elastin may be an interaction of the elastin protein with serum or arterial low density or very low density lipoproteins (LDL and VLDL) resulting in a transfer of lipids, but not of lipoprotein protein to the elastin. No significant lipid transfer occurred from the high density lipoproteins or chylomicrons. The amount of lipid taken up by plaque elastin was strikingly higher than by normal elastin and consisted mainly of cholesterol with over 80% of the cholesterol being cholesterol ester. The precondition for the lipid accumulation in plaque elastin appeared to be an altered amino acid composition of the elastin protein consisting of an increase in polar amino acids and a reduction in cross-linking amino acids. Subsequent treatment of lipoprotein-incubated arterial elastin with hot alkali and apolipoproteins did not reverse the binding of lipoprotein lipid to diseased elastin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346005"}
{"pmid": "4346000", "title": "Rifampicin, an antitrachoma antibiotic.", "content": "Rifampicin, an antitrachoma antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346000"}
{"pmid": "4346006", "title": "Direct measurement of osteolysis in man.", "content": "Direct measurement of osteolysis in man. Precise, direct measurement of bone calcium release (v(o-)) has been accomplished using a continuous tracer administration (CTA) technique. Dietary calcium (96.97% (40)Ca) is replaced by (40)Ca (99.991% (40)Ca) and blood levels of the naturally occuring isotope (48)Ca are monitored by neutron activation analysis as a function of time. (48)Ca abundance falls as this isotope is excreted and only partially replaced by release from bone. After a suitable period, an asymptotic abundance of (48)Ca in serum, E, is approached which is the fraction of the turnover rate of the rapidly exchangeable calcium pools coming from the skeleton (E = v(o-)/v(t)). E is determined with a standard error of 2%, providing a precise, sensitive index of v(o-). 13 studies in three normal men and one postmenopausal woman receiving maintenance estrogen show large intersubject variations in parameters of calcium metabolism using both CTA and pulse tracer administration (PTA) plus balance techniques. Induced hypercalcemia results in a prolonged decrease in v(o-). Glucocorticoid therapy initially and consistently induces a marked hypercalciuria while effects on most other parameters of calcium kinetics are variable. In two men E fell when testosterone was added to glucocorticoid treatment, consistent with the known antiosteolytic effect of androgens, despite the short period of study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346006"}
{"pmid": "4346007", "title": "Mechanism of the lower esophageal sphincter relaxation. Action of prostaglandin E 1  and theophylline.", "content": "Mechanism of the lower esophageal sphincter relaxation. Action of prostaglandin E 1  and theophylline. The intravenous injection of prostaglandin E(1) (PGE(1)) causes a dose-dependent relaxation of the lower esophageal sphincter (LES) in the intact, lightly anesthetized opossum. The action of PGE(1) is not inhibited by the drugs that produce muscarinic or nicotinic cholinergic antagonism or alpha and beta adrenergic antagonism in the doses that inhibited the action of respective agonists. Moreover, this action is not affected by exogenous gastrin pentapeptide. The action of PGE(1) on the LES is mimicked by isoproterenol, theophylline ethylenediamine, and dibutyryl cyclic AMP. Both theophylline, a phosphodiesterase inhibitor, and isoproterenol, an adenyl cyclase stimulator, added to the action of PGE(1). On the other hand, adenyl cyclase inhibitor nicotinic acid, as well as phosphodiesterase stimulator, imidazole inhibited its action. Further, both nicotinic acid and imidazole inhibited the degree of LES relaxation produced by esophageal distension. These studies suggest that intracellular cyclic AMP may act as the \"second messenger\" in the regulation of the lower esophageal sphincter relaxation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346007"}
{"pmid": "4346008", "title": "Activation of renal cortical adenylate cyclase by circulating immunoreactive parathyroid hormone fragments.", "content": "Activation of renal cortical adenylate cyclase by circulating immunoreactive parathyroid hormone fragments. Three distinct immunoreactive species of parathyroid hormone (PTH) are present in human serum. One has an estimated mol wt of 9,500 and probably represents glandular hormone, the second 7,000-7,500 mol wt, and the third 4,500-5,000 mol wt. In order to assess the biological activity of these circulating forms of PTH, we determined their ability to activate renal cortical adenylate cyclase. The 9,500 mol wt and 4,500-5,000 mol wt fractions produced four- to sixfold increases in cyclic 3',5'-AMP accumulation above control; the 7,000-7,500 mol wt fraction was inactive. None of the fragments had any effects on phosphodiesterase activity. Antiserum to bovine PTH did not block the activation of adenylate cyclase by either the gragments or bovine PTH. The data suggest that a large proportion of circulating immunoreactive human PTH is biologically active and that the biologically and immunologically active sites of the hormone are distinct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346008"}
{"pmid": "4346009", "title": "Studies on respiratory immunization with tetanus toxoid: the role of adjuvants.", "content": "Studies on respiratory immunization with tetanus toxoid: the role of adjuvants. Aerosol vaccination of mice with purified plain tetanus toxoid does not induce an immune response unless a suitable adjuvant is added.Aluminium phosphate is without effect by aerosol treatment. Killed cells of Klebsiella pneumoniae, although effective, are unsatisfactory owing to the long inhalation period needed.Killed Bordetella perussis cells were found to be an excellent adjuvant. A single aerosol treatment with a toxoid-B. pertussis mixture during a moderate exposure period evoked a considerable immune response. With repeated aerosol treatment of primed mice the addition of adjuvant is not required; booster treatment with plain toxoid is at least as effective.Extracts from B. pertussis cells exert as good an adjuvant effect as the whole-cell vaccine. The remaining cell-wall debris also appears to be an active adjuvant.In combination with constant doses of adjuvant (10(8)B. pertussis cells), the 50% protective doses (ED 50) of toxoid were determined by inhalation and by s.c. injection and were found to be 0.1875 and 0.0625 LFU respectively. This would imply that, as a result of the adjuvant action, the s.c. ED 50 is reduced by approximately a factor of 20; whereas the respiratory ED 50 is decreased by at least a factor of 100.It is suggested that the much more pronounced adjuvant activity in aerosol immunization is associated with the induction of strong cell-mediated hypersensitivity in the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346009"}
{"pmid": "4346010", "title": "Serological studies in a student population prone to infection with human papilloma virus.", "content": "Serological studies in a student population prone to infection with human papilloma virus. Four hundred and sixty-seven serum specimens from the female students at a residential college were examined for the presence of circulating antibody to human wart virus using the technique of counter-current immunoelectroosmophoresis. A significantly higher incidence of antibodies was found in students with a past history of plantar warts than in any other group. Antibody took several months to develop and was detectable in 20-30% of the students up to 9 years after infection. From a few cases of multiple infection, it was shown that reinfection could occur in spite of the presence of circulating antibodies probably of the IgG class. The sensitivity of the test was compared with two recognized techniques for detection of wart virus antibodies, namely gel diffusion and passive haemagglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346010"}
{"pmid": "4346011", "title": "Passive protection of mice against intracerebral infections with Bordetella pertussis.", "content": "Passive protection of mice against intracerebral infections with Bordetella pertussis. The passive protection of mice against an intracerebral infection with Bordetella pertussis, by antiserum introduced directly into the brain with the infecting organisms, was compared with the protection afforded by intraperitoneal antiserum. The antibody effective by the intracerebral route is that which is adsorbed onto the infecting organisms, although it does not affect the viability of the organisms in vitro in the absence of complement.PASSIVE PROTECTION AGAINST ORGANISMS INTRODUCED INTRACEREBRALLY TAKES PLACE IN ONE OF TWO WAYS, DEPENDING ON THE SIZE OF THE CHALLENGE: (1) after 3-4 days' growth, the growth rate declines so that the number of organisms does not reach the figure lethal for the mouse; (2) the organisms do not appear to multiply, as their numbers decline from the moment of injection, so that the brain is sterile after 2 days.Many of the mice protected against a challenge of 50,000 organisms (ca. 100 LD 50) by intraperitoneal or intracerebral antiserum recover by the first mechanism. The second mechanism operates after a smaller challenge of 5000 organisms (ca. 10 LD 50), irrespective of whether the antiserum is given intracerebrally with the challenge, or intraperitoneally within several hours of challenge. Too much antiserum given intracerebrally with a 50,000 challenge, but not with a 5000 challenge, inhibits protection.In some mice, virulent antibody-treated organisms which have not been killed, grow very slowly over a long period, but are eventually eliminated from the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346011"}
{"pmid": "4346003", "title": "The effect of the antibiotics distamycin A and congocidine on the replication of herpes simplex virus.", "content": "The effect of the antibiotics distamycin A and congocidine on the replication of herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346003"}
{"pmid": "4346012", "title": "Routine administration of oral polio vaccine in a subtropical area. Factors possibly influencing sero-conversion rates.", "content": "Routine administration of oral polio vaccine in a subtropical area. Factors possibly influencing sero-conversion rates. Poliomyelitis is an important problem of public health in warm-climate countries. Studies of serological responses to vaccination in these countries have given conflicting results but in many investigations the rates have been considerably less than in countries with temperate climates. In this study three possible factors influencing sero-conversion were investigated - the season of the year when vaccine was given, the social status of the mother (as indicated by the number of years of schooling) and the presence of non-poliomyelitis viruses (NPV) in the gut when vaccine was given.Over 200 children about 2 months of age were included in the study. Each was given three doses of trivalent vaccine at 6-week intervals.The sero-conversion rates of the groups fed in winter were excellent but were slightly less good in summer. The differences were greatest in children in the lower socio-economic groups and in children excreting other enteroviruses.The conclusions are that, provided a potent vaccine is used, the factors which diminish the effectiveness of immunization in warm-climate countries can be overcome: (1) by giving three doses of trivalent vaccine; (2) by beginning vaccination at the earliest possible age (when enteroviruses are fewest); (3) by concentrating special attention on the lower socio-economic groups and if necessary by giving a reinforcing dose several months after the third dose has been given - preferably in the colder months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346012"}
{"pmid": "4346013", "title": "Filamentous particles in human alveolar cell carcinomas: electron microscopy studies of six cases (preliminary report).", "content": "Filamentous particles in human alveolar cell carcinomas: electron microscopy studies of six cases (preliminary report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346013"}
{"pmid": "4346001", "title": "The natural history and diagnosis of herpes cornea.", "content": "The natural history and diagnosis of herpes cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346001"}
{"pmid": "4346002", "title": "Studies on the molecular biology of herpes simplex virus.", "content": "Studies on the molecular biology of herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346002"}
{"pmid": "4346014", "title": "Kaposi's sarcoma: a new model in the search for viruses associated with human malignancies.", "content": "Kaposi's sarcoma: a new model in the search for viruses associated with human malignancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346014"}
{"pmid": "4346015", "title": "Myoepithelioma with a leukemoid reaction in BALB-c mice.", "content": "Myoepithelioma with a leukemoid reaction in BALB-c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346015"}
{"pmid": "4346016", "title": "Isolation and properties of cells releasing C-type particles from BALB-c embryo cell cultures.", "content": "Isolation and properties of cells releasing C-type particles from BALB-c embryo cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346016"}
{"pmid": "4346004", "title": "Collagenolytic enzymes in corneal pathology.", "content": "Collagenolytic enzymes in corneal pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346004"}
{"pmid": "4346017", "title": "Fate of chromatin of interphase nuclei subjected to \"phosphasing\" in virus-fused cells.", "content": "Fate of chromatin of interphase nuclei subjected to \"phosphasing\" in virus-fused cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346017"}
{"pmid": "4346018", "title": "Impaired inflammatory response in tumor-bearing guinea pigs.", "content": "Impaired inflammatory response in tumor-bearing guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346018"}
{"pmid": "4346019", "title": "Virus-specific nucleic acids in simian virus 40-transformed hamster cell clones varying in oncogenic potential.", "content": "Virus-specific nucleic acids in simian virus 40-transformed hamster cell clones varying in oncogenic potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346019"}
{"pmid": "4346020", "title": "Feline malignant mammary tumors. I. Morphology and biology: some comparisons with human and canine mammary carcinomas.", "content": "Feline malignant mammary tumors. I. Morphology and biology: some comparisons with human and canine mammary carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346020"}
{"pmid": "4346021", "title": "Polygraphic sleep study in craniopagus twins (where is the sleep transmitter?).", "content": "Polygraphic sleep study in craniopagus twins (where is the sleep transmitter?). By means of polygraphic recordings complete independence of the sequence of sleeping and waking and of the two sleep states (REM and NREM) could be demonstrated in twins extensively conjoined at the skulls. Functionally important connections in the circulation of the two babies were found during subsequent preoperative investigations. These observations are at variance with the hypothesis of an extraneuronal humoral sleep-inducing factor based on crossed-circulation experiments in animals; moreover they raise a new question about the transportation of the sleepregulating biogenic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346021"}
{"pmid": "4346022", "title": "Interval analysis of repetitive denervation potentials of human skeletal muscle.", "content": "Interval analysis of repetitive denervation potentials of human skeletal muscle. Interval analyses of denervation potentials (fibrillation-potentials and positive sharp waves) in human skeletal muscles were performed using a DEC PDP-12 computer. Extremely small differences between consecutive intervals (usually less than 1%) and slow up and down drifts in the spontaneous discharge frequency were found to be characteristic of repetitive denervation potentials. These two findings are safe criteria for the clinical diagnosis of denervation and they may be superior to the more commonly used criteria based upon the shapes, amplitudes, and durations of the potentials. Physiological data from the literature as well as hypotheses relating to spontaneous activity are reviewed. Generator potentials across the muscle fibre membrane, lowered firing threshold, and constant-sized after-potentials are considered the basic factors relevant to spontaneous and rhythmical firing and to the slow drift observed in the firing frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346022"}
{"pmid": "4346023", "title": "Interaction between voluntary contraction and tonic stretch reflex transmission in normal and spastic patients.", "content": "Interaction between voluntary contraction and tonic stretch reflex transmission in normal and spastic patients. Transmission characteristics of tonic stretch reflex (TSR) pathways in both normal and spastic patients have been measured during different levels of sustained voluntary contraction of the biceps brachii muscle. A cross-correlation technique of analysis was used to separate reflex responses from the total electromyographic activity. TSR transmission in normal subjects was observed to change with the level of voluntary contraction; sensitivity to stretch increased approximately three-fold as the subject stiffened the arm by simultaneously contracting flexor and extensor muscles. In contrast, TSR transmission did not alter during voluntary contraction in spastic patients. It is proposed that in spastic patients supraspinal modulation of reflex transmission is impaired because hypersensitive spinal reflexes short-circuit long loop pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346023"}
{"pmid": "4346024", "title": "Nerve potentials and afferent conduction velocities in the differential diagnosis of amyotrophy of the hand.", "content": "Nerve potentials and afferent conduction velocities in the differential diagnosis of amyotrophy of the hand. Nerve action potentials recorded over the elbow after stimulation of the wrist were studied in patients with hand amyotrophy of different origin. In amyotrophic lateral sclerosis the amplitude of nerve action potentials does not change significantly even with extreme muscle wasting and loss of motor units.Studies of multisegmental afferent conduction velocities may demonstrate a strictly localized lesion with normal values above the compression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346024"}
{"pmid": "4346025", "title": "Corneal reflex in hemisphere disease.", "content": "Corneal reflex in hemisphere disease. The contralateral corneal reflex may be absent in patients with a deep lesion of the parietal lobe. Frontal and temporal lobe lesions apparently do not interfere with this reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346025"}
{"pmid": "4346026", "title": "Subacute spongiform encephalopathy. Electron microscopic studies.", "content": "Subacute spongiform encephalopathy. Electron microscopic studies. Electron microscopic changes in brain biopsies from two cases of subacute spongiform encephalopathy are described. Large vacuoles seen in astrocytic and neuronal processes were surrounded by one or more concentric membranes. Dense-core vesicles were found in axonal endings and in nerve cell perikarya; these particles could represent catecholamine-containing vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346026"}
{"pmid": "4346027", "title": "A method for the quantitative determination of urinary estriol conjugates in human pregnancy.", "content": "A method for the quantitative determination of urinary estriol conjugates in human pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346027"}
{"pmid": "4346028", "title": "Possible mechanisms of anesthesia.", "content": "Possible mechanisms of anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346028"}
{"pmid": "4346029", "title": "Alpha-fetoprotein as an aid for diagnosis of primary hepatoma.", "content": "Alpha-fetoprotein as an aid for diagnosis of primary hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346029"}
{"pmid": "4346030", "title": "Requirement of proteins S5 and S9 from 30S subunits for the ribosome-dependent GTPase activity of elongation factor G.", "content": "Requirement of proteins S5 and S9 from 30S subunits for the ribosome-dependent GTPase activity of elongation factor G. During CsCl isopycnic centrifugation at 20 mM Mg(++), Escherichia coli 30S ribosomal subunits specifically lose proteins S1, S2, S3, S5, S9, S10, and S14. The resultant 30S core is unable to stimulate the GTPase activity of EF-G in the presence of 50S subunits. Activity could be restored to a small extent by adding back S2, S5, or S9. However, when S5 and S9 were added together, they cooperatively produced 30S particles 1.5 times more active than the original native 30S subunits. The small amount of activity restored by S2 was simply additive to that restored by S5 or S9. None of the other split proteins showed any restoring capability. Ability of the various protein-deficient 30S particles to couple with 50S subunits corresponded closely to their activity in the EF-G GTPase reaction. It is concluded that S5 and S9 together enable the 30S subunit to participate in the formation of a GTPase-active 30S-50S-EF-G complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346030"}
{"pmid": "4346031", "title": "Malignant lymphomas of African children.", "content": "Malignant lymphomas of African children. Clinical, pathologic, and epidemiologic observations of malignant tumors of children in sub-Sahara Africa suggest alternative theories of causation, and give insight into environmental influences that may play a large role in the etiology and form of malignant lymphatic tumors and cerebral neoplasms of infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346031"}
{"pmid": "4346032", "title": "Prevention of simian virus 40 tumors by hamster fetal tissue: influence of parity status of donor females on immunogenicity of fetal tissue and on immune cell cytotoxicity.", "content": "Prevention of simian virus 40 tumors by hamster fetal tissue: influence of parity status of donor females on immunogenicity of fetal tissue and on immune cell cytotoxicity. Fetal tissue from primiparous hamsters prevented simian virus 40 (SV40) tumorigenesis in male hamsters, whereas fetal tissue from multiparous hamsters did not. The parity status of normal (uninoculated) hamsters also influenced the cytotoxicity of their lymphoid cells against tumor cells. Lymph node cells from nonpregnant primiparous and multiparous animals were cytotoxic in microcytotoxicity tests against SV40, polyoma, and adenovirus 7 tumor cells, but were not active against control BHK cells. Lymph node cells from virgin female donors were inactive. Peritoneal exudate cells from these donors reacted in similar fashion against SV40 tumor cells in vitro and in adoptive transfer tests in vivo. However, the cytotoxicity of peritoneal exudate cells from multiparous hamsters was greatly reduced during pregnancy, a time when noncytotoxic humoral antibody reactive with surface antigen of SV40 tumor cells is present. This humoral antibody is not detected during first pregnancy, and peritoneal exudate cells obtained from pregnant primiparous hamsters demonstrated a high degree of cytotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346032"}
{"pmid": "4346033", "title": "Release of infectious Epstein-Barr virus by transformed marmoset leukocytes.", "content": "Release of infectious Epstein-Barr virus by transformed marmoset leukocytes. Marmoset blood leukocytes transformed in vitro by Epstein-Barr virus regularly release extracellular infectious Epstein-Barr virus with high titers of transforming activity. By comparison, human umbilical cord leukocytes and adult human leukocytes transformed by Epstein-Barr virus release either no extracellular infectious virus or small amounts, irregularly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346033"}
{"pmid": "4346035", "title": "Mutagenic DNA polymerase in human leukemic cells.", "content": "Mutagenic DNA polymerase in human leukemic cells. Evidence is presented that DNA polymerases from human leukemic cells are mutagenic. Nucleic acid-free extracts of acute lymphoblastic leukemic cells polymerized about 10-times more dCTP using poly(dA-dT).poly(dA-dT) as a template than did extracts from normal lymphocytes. Mutagenic DNA polymerases could perhaps play an important role in tumor progression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346035"}
{"pmid": "4346034", "title": "Double-stranded RNA as an inhibitor of protein synthesis and as a substrate for a nuclease in extracts of Krebs II ascites cells.", "content": "Double-stranded RNA as an inhibitor of protein synthesis and as a substrate for a nuclease in extracts of Krebs II ascites cells. Concentrations of double-stranded RNA above about 0.1 mug/ml inhibit translation of encephalo-myocarditis viral RNA and mouse globin messenger RNA in extracts of Krebs II ascites cells. Protein synthesis initially proceeds at the control rate, then abruptly shuts off in a manner similar to that observed in reticulocyte lysates [Hunt, T. & Ehrenfeld, E. (1971) Nature New Biol. 230, 91-94]. Substantially higher concentrations of double-stranded RNA are required to give this effect in ascites extracts. Subcellular fractions of Krebs II ascites cells contain a nucleolytic activity capable of digesting several natural and synthetic double-stranded RNAs. This nuclease is most active under conditions of protein synthesis, and part of the activity remains associated with ribosomes upon sedimentation. It is probably because of digestion of double-stranded RNA by this nuclease that higher concentrations of double-stranded RNA are required for inhibition of protein synthesis in Krebs cell extracts than in reticulocyte lysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346034"}
{"pmid": "4346036", "title": "Structural characteristics of some murine RNA tumor viruses studied by lactoperoxidase iodination.", "content": "Structural characteristics of some murine RNA tumor viruses studied by lactoperoxidase iodination. Iodination by the noninvasive enzymatic lactoperoxidase technique has been used to study the enzyme-accessible and enzyme-inaccessible proteins of three oncorna viruses (radiation leukemia virus, Moloney leukemia virus, and mouse mammary tumor virus). The number and relative molecular weight of proteins associated with virion preparations purified on sucrose gradients were characterized by scans of Coomassie blue-stained bands after dodecyl sulfate-polyacrylamide gel electrophoresis. Gel scans from the leukemia viruses are similar, each showing six distinct major protein bands on stained gels. The mammary tumor virus proteins by this analysis are not similar to those of the leukemia viruses. Enzymatic iodination of intact virion preparations led to the solitary labeling of one of the major proteins of each virus-the 80,000-dalton protein of the leukemia viruses and the 52,500-dalton protein of the mammary tumor virus. These are tentatively positioned as surface (enzyme-accessible) moieties in the virions. Disruption of each virus with a nonionic nonionic detergent before enzymatic iodination led to the labeling of the remaining stainable bands. The four lower molecular weight bands of the leukemia viruses are tentatively positioned as internal (enzyme-inaccessible) components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346036"}
{"pmid": "4346037", "title": "Malignant transformation of BHK21 clone 13 cells in vitro by nitrosamines--a conditional state.", "content": "Malignant transformation of BHK21 clone 13 cells in vitro by nitrosamines--a conditional state. All the BHK(21) Clone 13 cells transformed by dimethylnitrosamine or nitrosomethylurea, and a single \"spontaneously\" transformed clone obtained in our laboratory, exhibit a conditional state of the transformed phenotype. Upon growth at 38.5 degrees , they have a transformed phenotype (clonal morphology and the ability to plate in soft agar); when grown at 32 degrees , their phenotype is normal. The conditional state of these cells, however, does not extend to their growth characteristics; their plating efficiency at the two temperatures in liquid medium is similar. Conversion from the normal to the transformed phenotype and the reverse is possible by temperature shifts. A working hypothesis is proposed suggesting that this phenomenon may be caused by a temperature-sensitive mutation of a cellular gene whose product is responsible for maintaining the normal phenotype. The high temperature would then affect either the synthesis or the function of the protein carrying the temperature-sensitive alteration and, as a consequence, the transformed phenotype would be expressed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346037"}
{"pmid": "4346038", "title": "Production of mucopolysaccharides by normal and transformed cells.", "content": "Production of mucopolysaccharides by normal and transformed cells. The rate of hyaluronic acid and sulfated mucopolysaccharide production was measured for hamster embryo fibroblasts and for general oncogenic lines derived by virus transformation. A striking increase in both the rate of hyaluronic acid synthesis and the amount of cell-associated polymer was observed after transformation by herpes simplex type-2 or SV40 virus. Although no corresponding change was observed for the sulfated polysaccharides, the proportion of heparan sulfate increased significantly after transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346038"}
{"pmid": "4346039", "title": "RNA related to that of a murine leukemia virus in Burkitt's tumors and nasopharyngeal carcinomas.", "content": "RNA related to that of a murine leukemia virus in Burkitt's tumors and nasopharyngeal carcinomas. RNA homologous to that of the Rauscher leukemia virus has been detected in Burkitt's lymphomas and nasopharyngeal carcinomas. Earlier excellent experimental evidence has linked these two human tumors with the Epstein-Barr virus, a DNA-containing agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346039"}
{"pmid": "4346040", "title": "Electron spin resonance studies of spin-labeled mammalian cells by detection of surface-membrane signals.", "content": "Electron spin resonance studies of spin-labeled mammalian cells by detection of surface-membrane signals. Lipid-soluble spin labels were incorporated into human lymphocytes and mouse L-cells and the resulting electron spin resonance spectra were compared with spectra obtained from similarly labeled human erythrocytes. Spin labels were found in all subcellular fractions of the nucleated cells that contained membranes. Spinlabeled cells remained viable and capable of replicating in vitro. Electron spin resonance signals from spin-labeled nucleated cells underwent a time- and temperature-dependent decay that was reversed by bathing the cells in K(3)Fe(CN)(6). The demonstration of a relative cell impermeability to ferricyanide, as measured by both colorimetric and radioisotopic label methods, indicated that only spin-labeled molecules in the surface membrane were reactivated when ferricyanide was added to spin-labeled cells after the electron spin resonance signal had decayed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346040"}
{"pmid": "4346041", "title": "Induction of cytolysis of cultured lymphoma cells by adenosine 3':5'-cyclic monophosphate and the isolation of resistant variants.", "content": "Induction of cytolysis of cultured lymphoma cells by adenosine 3':5'-cyclic monophosphate and the isolation of resistant variants. Cultured mouse lymphosarcoma cells are killed on exposure to 0.1 mM N(6),O(2')-dibutyryl-adenosine 3':5'-cyclic monophosphate. A population of cells resistant to the killing effect of dibutyryl cyclic AMP at concentrations as high as 1 mM was selected. The growth characteristics of the resistant cells were similar to those of the sensitive parental line. However, the resistant cells contain less cytoplasmic cyclic AMP-binding proteins and decreased cyclic AMP-stimulated protein kinase activity. It is proposed that transition from sensitivity to resistance to dibutyryl cyclic AMP in lymphoma cells is connected with a modification of the cyclic AMP-binding protein, which appears to be the regulatory subunit of the cyclic AMP-activated protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346041"}
{"pmid": "4346042", "title": "Pharmacology of the brain: the hippocampus, learning and seizures.", "content": "Pharmacology of the brain: the hippocampus, learning and seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346042"}
{"pmid": "4346045", "title": "Adenosine 3',5'-monophosphate: electrophysiological evidence for a role in synaptic transmission.", "content": "Adenosine 3',5'-monophosphate: electrophysiological evidence for a role in synaptic transmission. Synaptic potentials and changes in resting membrane potentials of superior cervical ganglia of the rabbit were measured in the presence of adenosine 3',5'-monophosphate and agents that affect its metabolism. Adenosine 3',5'-monophosphate and its mono- and dibutyryl derivatives caused a hyperpolarization of the postganglionic neurons. Theophylline potentiated the slow inhibitory postsynaptic potential that follows synaptic transmission, as well as the hyperpolarization of postganglionic neurons caused by exogenous dopamine. Conversely, prostaglandin E(1) inhibited both the slow inhibitory postsynaptic potential and the dopamine-induced hyperpolarization. We hypothesize that the slow inhibitory postsynaptic potential as well as the dopamine-induced hyperpolarization result from increased amounts of adenosine 3'5'-monophosphate in the postganglionic neurons. The dibutyryl derivative of guanosine 3'5'-monophosphate caused a depolarization of the postganglionic neurons, which is consistent with the possibility that guanosine 3'5'-monophosphate mediates synaptic transmission at muscarinic cholinergic synapses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346045"}
{"pmid": "4346046", "title": "Anaesthesia of fish.", "content": "Anaesthesia of fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346046"}
{"pmid": "4346051", "title": "Amounts of gonadotrophins required for normal follicular growth in hypophysectomized adult rats.", "content": "Amounts of gonadotrophins required for normal follicular growth in hypophysectomized adult rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346051"}
{"pmid": "4346052", "title": "Effect of progesterone on the time of ovulation in immature rats pretreated with pregnant mare's serum gonadotrophin (PMSG).", "content": "Effect of progesterone on the time of ovulation in immature rats pretreated with pregnant mare's serum gonadotrophin (PMSG). 21-day-old female rats maintained under 14 hours light and 10 hours darkness were used to determine if there is any effect of progesterone on the time of ovulation, time of release of pituitary gonadotropins (critical period), and the change  in plasma LH levels in immature rats pretreated with pregnant mare's serum gonadotropin (PMSG).  3 OR 12 IU PMSG was injected on Day 22, 7:00 - 8:00 A.M. Colony Time.  3 IU PMSG-treated rats were injected at 10:00 A.M. Day 24 with either .5 mg progesterone or 10 mcg estrone.  2 groups of 3 IU PMSG rats were given .5 or 2 mg progesterone at 5:30 A.M., Day 24.  Time of ovulation was determined by sacrificing rats every 30 minutes from midnight - 4:00 A.M. and at 8:00 A.M. on Day 25.  In 2 experiments rats primed with 3 or 12 IU PMSG were injected with 2 mg progesterone at 5:30 A.M. on Day 24 followed by 4.5 mg phenobarbital from 5:30 - 4:00 P.M.  Samples for LH assay were taken at 6:00 A.M., 10:00 A.M., 3:00 P.M., and 8:00 P.M. Day 24 and 9:00 A.M., Day 25.  23-day-old Holtzman rats were used for LH assay.  50 IU PMSG and 25 IU HCG were given between 10:00 and 11:00 A.M., Day 25, or 4:00 and 5:00 P.M., Day 27, respectively, with daily injections of 10 mcg estradiol-3-benzoate Days 30-38.  Assay was performed when rats were 39 days old by the method of bogdanove and Gay.  The concentration of ascorbin acid was determined by the method of Mindlin and Butler.  Duncan's multiple range was used to calculate significance.  Ovulation time of 3 IU PMSG-primed rats was between 1:00 and 4:00 A.M. on Day 25 as determined by presence of ova in the oviducts.  Time of ovulation was 1:00 - 2:00 A.M., Day 25, when .5 mg progesterone was given at 10:00 A.M., Day 24.  Ovulation occurred at 11:00 P.M., Day 24 when .5 or 2 mg progesterone was injected at 5:30 A.M., Day 24.  12 IU PMSG-treated rats had ovulation occur 10:00 P.M., Day 24 - 2:00 A.M., Day 25 when 2 mg progesterone was given 5:30 A.M., Day 24.  4.5 mg phenobarbital given at 10:30 or 11:00 A.M. Day 24 in rats treated with 3 or 12 IU PMSG respectively inhibited ovulation, indicating the critical period had been shifted forward by 3 hours.  Highest level of LH was present in 3:00 and 8:00 P.M. plasma, Day 24 in rats primed with 3 IU PMSG alone and at 10:00 A.M. and 3:00 P.M., Day 24 when progesterone was also given.  Progesterone advanced the time of ovulation by shifting the critical period and causing an adequate release of ovulatory gonadotropins 10:00 - 3:00 P.M. on the day preceding ovulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346052"}
{"pmid": "4346053", "title": "C 21  steroid metabolism and conjugation in the human premature neonate. 2. Tissue metabolism and conjugation of exogenous cortisol, 11-deoxycortisol, corticosterone and pregnenolone in the presence and absence of ACTH in vitro.", "content": "C 21  steroid metabolism and conjugation in the human premature neonate. 2. Tissue metabolism and conjugation of exogenous cortisol, 11-deoxycortisol, corticosterone and pregnenolone in the presence and absence of ACTH in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346053"}
{"pmid": "4346054", "title": "Imitation of the adreno-cortical response to surgery by intravenous infusion of synthetic human ACTH.", "content": "Imitation of the adreno-cortical response to surgery by intravenous infusion of synthetic human ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346054"}
{"pmid": "4346056", "title": "Reduction malformations and chromosome anomalies.", "content": "Reduction malformations and chromosome anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346056"}
{"pmid": "4346057", "title": "Undifferentiated lymphoma, non-Burkitt's type. Meningeal and bone marrow involvement in children.", "content": "Undifferentiated lymphoma, non-Burkitt's type. Meningeal and bone marrow involvement in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346057"}
{"pmid": "4346058", "title": "Estrogen treatment of tall girls.", "content": "Estrogen treatment of tall girls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346058"}
{"pmid": "4346059", "title": "Development of hip dysplasia in dogs.", "content": "Development of hip dysplasia in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346059"}
{"pmid": "4346060", "title": "Mechanisms of platelet function as revealed by the retention of platelets in glass bead columns.", "content": "Mechanisms of platelet function as revealed by the retention of platelets in glass bead columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346060"}
{"pmid": "4346061", "title": "Adhesion of platelets to subendothelium.", "content": "Adhesion of platelets to subendothelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346061"}
{"pmid": "4346062", "title": "The control of platelet responsiveness by agents that influence cyclic AMP metabolism.", "content": "The control of platelet responsiveness by agents that influence cyclic AMP metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346062"}
{"pmid": "4346050", "title": "Psammoma bodies found in cervico-vaginal smears.", "content": "Psammoma bodies found in cervico-vaginal smears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346050"}
{"pmid": "4346063", "title": "Cyclic 3',5'-adenosine monophosphate in human blood platelets. IV. Regulatory role of cyclic amp in platelet function.", "content": "Cyclic 3',5'-adenosine monophosphate in human blood platelets. IV. Regulatory role of cyclic amp in platelet function. Evidence which bears on the hypothesis that agents that increase platelet cyclic adenosine 3',5' monophosphate (cAMP) tend to inhibit platelet aggregation, whereas agents whose action is to induce or augment platelet aggregation are associated with a decrease in platelet content of this cyclic nucleotide is reviewed.  Using radiolabeled cAMP in incubation with various agents, it was found that caffeine, colagen, thrombin, prostaglandins E1 and E2, and phosphodiesterase inhibitors are all agents that increase platelet cAMP and inhibit platelet aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346063"}
{"pmid": "4346065", "title": "Purification and properties of cytochrome c (550: Hemispora stellata).", "content": "Purification and properties of cytochrome c (550: Hemispora stellata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346065"}
{"pmid": "4346067", "title": "Rapid single-step kinetic colorimetric assay for lactate dehydrogenase in serum.", "content": "Rapid single-step kinetic colorimetric assay for lactate dehydrogenase in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346067"}
{"pmid": "4346068", "title": "Polyacrylamide-gel disc-electrophoresis as a screening procedure for serum lipoprotein abnormalities.", "content": "Polyacrylamide-gel disc-electrophoresis as a screening procedure for serum lipoprotein abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346068"}
{"pmid": "4346069", "title": "Polyacrylamide-gel block-electrophoresis of plasma lipoproteins.", "content": "Polyacrylamide-gel block-electrophoresis of plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346069"}
{"pmid": "4346070", "title": "Automated kinetic spectrophotometric assays of enzyme activities of human cerebrospinal fluid: methods and reference values.", "content": "Automated kinetic spectrophotometric assays of enzyme activities of human cerebrospinal fluid: methods and reference values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346070"}
{"pmid": "4346072", "title": "Additional observations on hydrochlorothiazide interference with measurement of total urinary placental estrogens.", "content": "Additional observations on hydrochlorothiazide interference with measurement of total urinary placental estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346072"}
{"pmid": "4346071", "title": "Identification of lithocholic acid and measurement of other bile acids in serum of healthy humans.", "content": "Identification of lithocholic acid and measurement of other bile acids in serum of healthy humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346071"}
{"pmid": "4346073", "title": "Enzyme determinations: criticisms of some recent reports.", "content": "Enzyme determinations: criticisms of some recent reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346073"}
{"pmid": "4346074", "title": "The lipid composition of the larval nervous system of Musca domestica. A comparison between insects susceptible and resistant to cyclodiene insecticides.", "content": "The lipid composition of the larval nervous system of Musca domestica. A comparison between insects susceptible and resistant to cyclodiene insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346074"}
{"pmid": "4346077", "title": "Experimental ocular studies with polyinosinic acid: polycytidylic acid.", "content": "Experimental ocular studies with polyinosinic acid: polycytidylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346077"}
{"pmid": "4346080", "title": "Subcellular localization of avian leucosis group-specific complement-fixing antigens in mouse ascites sarcoma cells (SR-C3H-He cells) induced by Schmidt-Ruppin strain of Rous sarcoma virus.", "content": "Subcellular localization of avian leucosis group-specific complement-fixing antigens in mouse ascites sarcoma cells (SR-C3H-He cells) induced by Schmidt-Ruppin strain of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346080"}
{"pmid": "4346081", "title": "Mitochondrial oxidation of 3,3'-diaminobenzidine and related compounds, and their possible relation to carcinogenesis.", "content": "Mitochondrial oxidation of 3,3'-diaminobenzidine and related compounds, and their possible relation to carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346081"}
{"pmid": "4346082", "title": "Mechanism of antitumor action of dimethanesulfonylthiopentane.", "content": "Mechanism of antitumor action of dimethanesulfonylthiopentane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346082"}
{"pmid": "4346083", "title": "Transplacental carcinogenesis by urethan in mice: teratogenesis and carcinogenesis in relation to organogenesis.", "content": "Transplacental carcinogenesis by urethan in mice: teratogenesis and carcinogenesis in relation to organogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346083"}
{"pmid": "4346084", "title": "Immunohistological studies on mucosal glycoprotein in rectal carcinoma.", "content": "Immunohistological studies on mucosal glycoprotein in rectal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346084"}
{"pmid": "4346086", "title": "Hepatocarcinogenicity of polychlorinated biphenyls in mice.", "content": "Hepatocarcinogenicity of polychlorinated biphenyls in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346086"}
{"pmid": "4346085", "title": "Deviations in isozyme patterns of acid phosphatase and esterase, and in ultrastructures of Yoshida ascites hepatomas from rat hepatocytes.", "content": "Deviations in isozyme patterns of acid phosphatase and esterase, and in ultrastructures of Yoshida ascites hepatomas from rat hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346085"}
{"pmid": "4346088", "title": "Effects of crystalline environment on pyrimidine free-radical formation: barbital crystal polymorphs and sodium barbital.", "content": "Effects of crystalline environment on pyrimidine free-radical formation: barbital crystal polymorphs and sodium barbital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346088"}
{"pmid": "4346089", "title": "Aquaculture and associated diseases of fish of public health importance.", "content": "Aquaculture and associated diseases of fish of public health importance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346089"}
{"pmid": "4346076", "title": "Inhibition in vitro of cyclic 3',5' nucleotide phosphodiesterase activity by drugs.", "content": "Inhibition in vitro of cyclic 3',5' nucleotide phosphodiesterase activity by drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346076"}
{"pmid": "4346090", "title": "Calcium-mediated effects of calcitonin on cyclic AMP formation and lymphoblast proliferation in thymocyte populations exposed to prostaglandin E 1 .", "content": "Calcium-mediated effects of calcitonin on cyclic AMP formation and lymphoblast proliferation in thymocyte populations exposed to prostaglandin E 1 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346090"}
{"pmid": "4346091", "title": "Ammonia effects in cultures of normal and transformed 3T3 cells.", "content": "Ammonia effects in cultures of normal and transformed 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346091"}
{"pmid": "4346092", "title": "Biochemical characteristics of normal and virally transformed mouse cell lines.", "content": "Biochemical characteristics of normal and virally transformed mouse cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346092"}
{"pmid": "4346094", "title": "Induction of reagin synthesis in the rat with associated and dissociated hemocyanin: effect of antilymphocyte serum.", "content": "Induction of reagin synthesis in the rat with associated and dissociated hemocyanin: effect of antilymphocyte serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346094"}
{"pmid": "4346096", "title": "Infection of thymus cells in vivo and in vitro with a guinea pig herpes-like virus and the effect of antibody on virus replication in organ culture.", "content": "Infection of thymus cells in vivo and in vitro with a guinea pig herpes-like virus and the effect of antibody on virus replication in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346096"}
{"pmid": "4346095", "title": "Proportion of T and B lymphocytes in lesions of Marek's disease: theoretical implications for pathogenesis.", "content": "Proportion of T and B lymphocytes in lesions of Marek's disease: theoretical implications for pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346095"}
{"pmid": "4346097", "title": "In vitro assay of cellular immunity to tumor-specific antigen(s) of virus-induced tumors by macrophage migration inhibition.", "content": "In vitro assay of cellular immunity to tumor-specific antigen(s) of virus-induced tumors by macrophage migration inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346097"}
{"pmid": "4346098", "title": "Preliminary x-ray studies of a cytochrome c from Micrococcus dentrificans.", "content": "Preliminary x-ray studies of a cytochrome c from Micrococcus dentrificans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346098"}
{"pmid": "4346099", "title": "Circularity and cross-linking in preparations of replicative form of encephalomyocarditis virus RNA.", "content": "Circularity and cross-linking in preparations of replicative form of encephalomyocarditis virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346099"}
{"pmid": "4346101", "title": "Cytokinesis in the stratum intermedium of the rat molar enamel organ.", "content": "Cytokinesis in the stratum intermedium of the rat molar enamel organ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346101"}
{"pmid": "4346100", "title": "Ultrastructural changes in Osmunda regalis Prothalli induced by X-irradiation.", "content": "Ultrastructural changes in Osmunda regalis Prothalli induced by X-irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346100"}
{"pmid": "4346102", "title": "Crystalline inclusion bodies in the epididymis of the nine-banded armadillo.", "content": "Crystalline inclusion bodies in the epididymis of the nine-banded armadillo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346102"}
{"pmid": "4346093", "title": "Acute herpetic gingivostomatitis in children.", "content": "Acute herpetic gingivostomatitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346093"}
{"pmid": "4346103", "title": "Electron microscopy of artichoke mottled crinkle virus in leaves of Chenopodium quinoa Willd.", "content": "Electron microscopy of artichoke mottled crinkle virus in leaves of Chenopodium quinoa Willd.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346103"}
{"pmid": "4346104", "title": "Contribution of polysynaptic pathways to the tonic vibration reflex.", "content": "Contribution of polysynaptic pathways to the tonic vibration reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346104"}
{"pmid": "4346105", "title": "The positive after-potential following the orthodromic and antidromic propagated impulses in the frog muscle spindle.", "content": "The positive after-potential following the orthodromic and antidromic propagated impulses in the frog muscle spindle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346105"}
{"pmid": "4346107", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 8-1973.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 8-1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346107"}
{"pmid": "4346108", "title": "Ski-boot neuropathy.", "content": "Ski-boot neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346108"}
{"pmid": "4346109", "title": "West Germany's geriatric patients: community care and after-care.", "content": "West Germany's geriatric patients: community care and after-care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346109"}
{"pmid": "4346110", "title": "Actions of adrenal, hypophysial and renal hormones on the renal excretion of water and electrolytes.", "content": "Actions of adrenal, hypophysial and renal hormones on the renal excretion of water and electrolytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346110"}
{"pmid": "4346118", "title": "Effect of colchicine on the fine structure of the neuromuscular junction.", "content": "Effect of colchicine on the fine structure of the neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346118"}
{"pmid": "4346120", "title": "Nervous system of the snail Helix aspersa. 3. Electron microscopic study of neurosecretory nerves and endings in the ganglionic sheath.", "content": "Nervous system of the snail Helix aspersa. 3. Electron microscopic study of neurosecretory nerves and endings in the ganglionic sheath.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346120"}
{"pmid": "4346119", "title": "Fine structure of the neural sheath, glia and neurons in the brain of the housefly, Musca domestica.", "content": "Fine structure of the neural sheath, glia and neurons in the brain of the housefly, Musca domestica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346119"}
{"pmid": "4346122", "title": "Studies of the fine structure of ovarian interstitial tissue. 7. The postnatal evolution of the thecal gland in the domestic fowl.", "content": "Studies of the fine structure of ovarian interstitial tissue. 7. The postnatal evolution of the thecal gland in the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346122"}
{"pmid": "4346124", "title": "Intrinsic autoregulatory control of heart rate and its applied and clinical implications.", "content": "Intrinsic autoregulatory control of heart rate and its applied and clinical implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346124"}
{"pmid": "4346123", "title": "Neuro-epithelial bodies in the respiratory mucosa of various mammals. A light optical, histochemical and ultrastructural investigation.", "content": "Neuro-epithelial bodies in the respiratory mucosa of various mammals. A light optical, histochemical and ultrastructural investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346123"}
{"pmid": "4346125", "title": "Histochemical studies on the morphology of the Golgi apparatus and on the distribution of hexokinase and some enzymes concerning vitamin C synthesis in the substantia nigra of the rabbit.", "content": "Histochemical studies on the morphology of the Golgi apparatus and on the distribution of hexokinase and some enzymes concerning vitamin C synthesis in the substantia nigra of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346125"}
{"pmid": "4346126", "title": "The dynamics of histochemical changes in the epithelium of the small intestine of mice after experimental intraperitoneal intoxication with benzene.", "content": "The dynamics of histochemical changes in the epithelium of the small intestine of mice after experimental intraperitoneal intoxication with benzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346126"}
{"pmid": "4346128", "title": "The avian intestinal flora with particular reference to the possible ecological significance of the cecal anaerobic bacteria.", "content": "The avian intestinal flora with particular reference to the possible ecological significance of the cecal anaerobic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346128"}
{"pmid": "4346131", "title": "Home hemodialysis.", "content": "Home hemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346131"}
{"pmid": "4346130", "title": "The etiology of respiratory tract infections in a tropical country.", "content": "The etiology of respiratory tract infections in a tropical country.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346130"}
{"pmid": "4346132", "title": "Chlorpropamide in diabetes insipidus.", "content": "Chlorpropamide in diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346132"}
{"pmid": "4346133", "title": "The isolation and chemical composition of premelanosomes and melanosomes: human and mouse melanomas.", "content": "The isolation and chemical composition of premelanosomes and melanosomes: human and mouse melanomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346133"}
{"pmid": "4346134", "title": "Abnormal tryptophan metabolism in patients with scurvy-type skin.", "content": "Abnormal tryptophan metabolism in patients with scurvy-type skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346134"}
{"pmid": "4346135", "title": "The group estimation of urinary 11-oxy-17-hydroxy-corticosteroids using gas-liquid chromatography.", "content": "The group estimation of urinary 11-oxy-17-hydroxy-corticosteroids using gas-liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346135"}
{"pmid": "4346137", "title": "Insulin from individual isolated mouse islets of Langerhans.", "content": "Insulin from individual isolated mouse islets of Langerhans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346137"}
{"pmid": "4346136", "title": "Atachment of normal and transformed hamster kidney cells to substrata varying in chemical composition.", "content": "Atachment of normal and transformed hamster kidney cells to substrata varying in chemical composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346136"}
{"pmid": "4346144", "title": "Effects of angiotensin I and antiotensin II on canine hepatic vascular resistance.", "content": "Effects of angiotensin I and antiotensin II on canine hepatic vascular resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346144"}
{"pmid": "4346145", "title": "Trypanosoma gambiense: cytopathologic changes in guinea pig hepatocytes.", "content": "Trypanosoma gambiense: cytopathologic changes in guinea pig hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346145"}
{"pmid": "4346146", "title": "Enzymes of coccidia: purification and properties of L-lactate dehydrogenase from Eimeria stiedae.", "content": "Enzymes of coccidia: purification and properties of L-lactate dehydrogenase from Eimeria stiedae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346146"}
{"pmid": "4346150", "title": "Comparative studies of lipid content and lipid metabolism of normal and transformed mouse cells.", "content": "Comparative studies of lipid content and lipid metabolism of normal and transformed mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346150"}
{"pmid": "4346151", "title": "Kinetics of incorporation of ( 32 P)phosphate into phospholipids of a SV 40 transformed mouse cell during logarithmic growth.", "content": "Kinetics of incorporation of ( 32 P)phosphate into phospholipids of a SV 40 transformed mouse cell during logarithmic growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346151"}
{"pmid": "4346152", "title": "Glycolipids of mouse fibroblasts and virus transformed mouse cell lines.", "content": "Glycolipids of mouse fibroblasts and virus transformed mouse cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346152"}
{"pmid": "4346153", "title": "Steroidglucuronyltransferases. 3. Oestradiol-17  3-glucuronyltransferase of the mitochondria of pig intestine.", "content": "Steroidglucuronyltransferases. 3. Oestradiol-17  3-glucuronyltransferase of the mitochondria of pig intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346153"}
{"pmid": "4346155", "title": "Comparison of the biological, biophysical and antigenic properties of four strains of infectious bovine rhinotracheitis herpesvirus.", "content": "Comparison of the biological, biophysical and antigenic properties of four strains of infectious bovine rhinotracheitis herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346155"}
{"pmid": "4346154", "title": "Steroidglucuronyltransferases. IV. Localization of the oestradiol-17 -glucuronyltransferase in the outer membrane of the mitochondria of pig intestine.", "content": "Steroidglucuronyltransferases. IV. Localization of the oestradiol-17 -glucuronyltransferase in the outer membrane of the mitochondria of pig intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346154"}
{"pmid": "4346156", "title": "Pathogenesis of meningo-encephalitis produced in calves by infectious bovine rhinotracheitis herpesvirus.", "content": "Pathogenesis of meningo-encephalitis produced in calves by infectious bovine rhinotracheitis herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346156"}
{"pmid": "4346157", "title": "Pathogenicity of Talfan and Konratice strains of Teschen virus in gnotobiotic pigs.", "content": "Pathogenicity of Talfan and Konratice strains of Teschen virus in gnotobiotic pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346157"}
{"pmid": "4346159", "title": "The Merkel cell.", "content": "The Merkel cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346159"}
{"pmid": "4346158", "title": "Infection of some species of African wild life with foot-and-mouth disease virus.", "content": "Infection of some species of African wild life with foot-and-mouth disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346158"}
{"pmid": "4346160", "title": "A preliminary crystallographic investigation of rice cytochrome c.", "content": "A preliminary crystallographic investigation of rice cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346160"}
{"pmid": "4346163", "title": "Effects of oral contraceptives on the renin-angiotensin system and on blood pressure of normal young women.", "content": "Effects of oral contraceptives on the renin-angiotensin system and on blood pressure of normal young women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346163"}
{"pmid": "4346164", "title": "Epidemiology of acute lower respiratory disease in children.", "content": "Epidemiology of acute lower respiratory disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346164"}
{"pmid": "4346165", "title": "Acute promyelocytic leukemia in pregnancy.", "content": "Acute promyelocytic leukemia in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346165"}
{"pmid": "4346167", "title": "EEG delta activity during human sleep as a damped ultradian rhythm.", "content": "EEG delta activity during human sleep as a damped ultradian rhythm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346167"}
{"pmid": "4346168", "title": "Haematemesis caused by oesophageal varices.", "content": "Haematemesis caused by oesophageal varices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346168"}
{"pmid": "4346166", "title": "Diagnosis and treatment of hirsutism in women.", "content": "Diagnosis and treatment of hirsutism in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346166"}
{"pmid": "4346169", "title": "Serum lipoprotein patterns in Bantu and Indian patients with nephrotic syndrome.", "content": "Serum lipoprotein patterns in Bantu and Indian patients with nephrotic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346169"}
{"pmid": "4346170", "title": "Cyclic adenosine monophosphate and hypertension in rats.", "content": "Cyclic adenosine monophosphate and hypertension in rats. Aortas from spontaneously hypertensive and stress hypertensive rats contained significantly lower intracellular concentrations of cyclic adenosine monophosphate than did their respective controls. Adenylate cyclase activity was normal but was less responsive to stimulation, while phosphodiesterase activity (especially the low Michaelis-Menten constant form) was significantly elevated. Human aortas contained two forms of phosphodiesterase that were similar to those in rat aortas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346170"}
{"pmid": "4346171", "title": "Virologic studies of generalized herpes zoster.", "content": "Virologic studies of generalized herpes zoster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346171"}
{"pmid": "4346185", "title": "A psychophysiological study of nightmares and night terrors. The suppression of stage 4 night terrors with diazepam.", "content": "A psychophysiological study of nightmares and night terrors. The suppression of stage 4 night terrors with diazepam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346185"}
{"pmid": "4346187", "title": "Determination of plasma renin activity by radioimmunoassay of angiotensin I.", "content": "Determination of plasma renin activity by radioimmunoassay of angiotensin I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346187"}
{"pmid": "4346186", "title": "Monkeypox virus (MPV). I. Propagation, purification, and further characterization.", "content": "Monkeypox virus (MPV). I. Propagation, purification, and further characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346186"}
{"pmid": "4346188", "title": "Increase of plasma renin-substrate concentration after infusion of angiotensin in the rat.", "content": "Increase of plasma renin-substrate concentration after infusion of angiotensin in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346188"}
{"pmid": "4346183", "title": "Monitoring of neuromuscular transmission in anesthetized man by a bulb-transducer assembly.", "content": "Monitoring of neuromuscular transmission in anesthetized man by a bulb-transducer assembly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346183"}
{"pmid": "4346189", "title": "Evidence for free radical involvement in the hydroxylation of proline: inhibition by nitro blue tetrazolium.", "content": "Evidence for free radical involvement in the hydroxylation of proline: inhibition by nitro blue tetrazolium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346189"}
{"pmid": "4346207", "title": "Computer evaluation to the x-ray densitometry method for the diagnosis of calcipenic osteopathy.", "content": "Computer evaluation to the x-ray densitometry method for the diagnosis of calcipenic osteopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346207"}
{"pmid": "4346215", "title": "The responses in culture of human tumour astrocytes and neuroblasts to N 6 , O 2' -dibutyryl adenosine 3',5'-monophosphoric acid.", "content": "The responses in culture of human tumour astrocytes and neuroblasts to N 6 , O 2' -dibutyryl adenosine 3',5'-monophosphoric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346215"}
{"pmid": "4346216", "title": "Thiamin deficiency: liver metabolite levels and redox and phosphorylation states in thiamin-deficient rats.", "content": "Thiamin deficiency: liver metabolite levels and redox and phosphorylation states in thiamin-deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346216"}
{"pmid": "4346218", "title": "Malignant lymphoma and nephrotic syndrome. A clinicopathologic analysis with light, immunofluorescence, and electron microscopy of the renal lesions.", "content": "Malignant lymphoma and nephrotic syndrome. A clinicopathologic analysis with light, immunofluorescence, and electron microscopy of the renal lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346218"}
{"pmid": "4346217", "title": "Vitamin A and bone metabolism in the rat.", "content": "Vitamin A and bone metabolism in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346217"}
{"pmid": "4346219", "title": "Malignant mixed mullerian tumor of the cervix following cyclophosphamide therapy for nephrotic syndrome.", "content": "Malignant mixed mullerian tumor of the cervix following cyclophosphamide therapy for nephrotic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346219"}
{"pmid": "4346220", "title": "Hyperthyroidism induced by trophoblastic thyrotropin.", "content": "Hyperthyroidism induced by trophoblastic thyrotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346220"}
{"pmid": "4346221", "title": "New drugs for treatment of Paget's disease.", "content": "New drugs for treatment of Paget's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346221"}
{"pmid": "4346222", "title": "Diplovax. A new oral polio vaccine.", "content": "Diplovax. A new oral polio vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346222"}
{"pmid": "4346223", "title": "Inactivation of Q beta RNA by electrophiles.", "content": "Inactivation of Q beta RNA by electrophiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346223"}
{"pmid": "4346224", "title": "Genetical behaviour of vesicular stomatitis virus during successive passages at high and low temperatures.", "content": "Genetical behaviour of vesicular stomatitis virus during successive passages at high and low temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346224"}
{"pmid": "4346225", "title": "Genetic analysis of replicating instabilities in yeast.", "content": "Genetic analysis of replicating instabilities in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346225"}
{"pmid": "4346227", "title": "Cytogenetic effects of hycanthone in the rat.", "content": "Cytogenetic effects of hycanthone in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346227"}
{"pmid": "4346226", "title": "Cytogenetic and mutagenic effects of DDT and DDE in a Chinese hamster cell line.", "content": "Cytogenetic and mutagenic effects of DDT and DDE in a Chinese hamster cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346226"}
{"pmid": "4346228", "title": "Demonstration by electron microscopy of viruses in cells found by light microscopy to contain inclusion bodies.", "content": "Demonstration by electron microscopy of viruses in cells found by light microscopy to contain inclusion bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346228"}
{"pmid": "4346229", "title": "Long survival in a male with 18-trisomy syndrome and Wilms' tumor: a subsequent report.", "content": "Long survival in a male with 18-trisomy syndrome and Wilms' tumor: a subsequent report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346229"}
{"pmid": "4346230", "title": "Role of adenosine 3',5'-monophosphate (cyclic AMP) in actions of catecholamines.", "content": "Role of adenosine 3',5'-monophosphate (cyclic AMP) in actions of catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346230"}
{"pmid": "4346231", "title": "Effect of angiotensin II on arterial blood pressure, glomerular filtration rate and urinary sodium excretion in normal, pregnant and hypertensive rats.", "content": "Effect of angiotensin II on arterial blood pressure, glomerular filtration rate and urinary sodium excretion in normal, pregnant and hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346231"}
{"pmid": "4346233", "title": "Percutaneous adrenal venography in the dog.", "content": "Percutaneous adrenal venography in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346233"}
{"pmid": "4346234", "title": "The all-ulnar hand.", "content": "The all-ulnar hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346234"}
{"pmid": "4346235", "title": "Parametric evaluation of the prevalence of Entamoeba histolytica infections in Ibadan.", "content": "Parametric evaluation of the prevalence of Entamoeba histolytica infections in Ibadan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346235"}
{"pmid": "4346237", "title": "The fine structure of the sporozoites of Isospora canis.", "content": "The fine structure of the sporozoites of Isospora canis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346237"}
{"pmid": "4346238", "title": "Ultrastructural study of microsporidian invasion into cells.", "content": "Ultrastructural study of microsporidian invasion into cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346238"}
{"pmid": "4346239", "title": "Study on parainfluenza virus type 1 isolated from pigs.", "content": "Study on parainfluenza virus type 1 isolated from pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346239"}
{"pmid": "4346240", "title": "Vitamin D-resistant rickets and hemophilia A--lack of close linkage on the X chromosome.", "content": "Vitamin D-resistant rickets and hemophilia A--lack of close linkage on the X chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346240"}
{"pmid": "4346242", "title": "The effects of gallamine on nerve terminals and endplates.", "content": "The effects of gallamine on nerve terminals and endplates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346242"}
{"pmid": "4346241", "title": "Variability of  -galactosidase A and B in different tissues of man.", "content": "Variability of  -galactosidase A and B in different tissues of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346241"}
{"pmid": "4346247", "title": "The mechanism of inhibition by fluoride of mitochondrial fatty acid oxidation.", "content": "The mechanism of inhibition by fluoride of mitochondrial fatty acid oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346247"}
{"pmid": "4346249", "title": "Cyclic 3',5'-adenosine monophosphate-dependent protein kinase of skin. I. Measurement and properties.", "content": "Cyclic 3',5'-adenosine monophosphate-dependent protein kinase of skin. I. Measurement and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346249"}
{"pmid": "4346250", "title": "Cyclic 3',5'-adenosine monophosphate-dependent protein kinase of skin. II. Levels in atopic dermatitis and psoriasis.", "content": "Cyclic 3',5'-adenosine monophosphate-dependent protein kinase of skin. II. Levels in atopic dermatitis and psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346250"}
{"pmid": "4346248", "title": "Factors controlling the rate of fatty acid  -oxidation in rat liver mitochondria.", "content": "Factors controlling the rate of fatty acid  -oxidation in rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346248"}
{"pmid": "4346254", "title": "Virus studies in the treatment of congenital cytomegalovirus infections by cytosine arabinoside.", "content": "Virus studies in the treatment of congenital cytomegalovirus infections by cytosine arabinoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346254"}
{"pmid": "4346255", "title": "Determination of the molecular weight of human gamma-3 chains by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate.", "content": "Determination of the molecular weight of human gamma-3 chains by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346255"}
{"pmid": "4346257", "title": "The persistence of tissue-specific antigen in muscle cells growing in vitro.", "content": "The persistence of tissue-specific antigen in muscle cells growing in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346257"}
{"pmid": "4346256", "title": "The effect of anti-lymphocytic antibody on the humoral immune response in different strains of mice. I. The response to bovine serum albumin.", "content": "The effect of anti-lymphocytic antibody on the humoral immune response in different strains of mice. I. The response to bovine serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346256"}
{"pmid": "4346260", "title": "Adrenocorticotropin. 43. The synthesis and steroidogenic activity of (2-N-methylphenylalanine)-adrenocorticotropin-(1-19).", "content": "Adrenocorticotropin. 43. The synthesis and steroidogenic activity of (2-N-methylphenylalanine)-adrenocorticotropin-(1-19).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346260"}
{"pmid": "4346261", "title": "Studies on L-glycerol-3-phosphate dehydrogenases in Japanese quail, Coturnix coturnix japonica. I. Multiple components and some enzymatic properties of nicotinamide adenine dinucleotide-linked L-glycerol-3-phosphate dehydrogenase from liver and testes.", "content": "Studies on L-glycerol-3-phosphate dehydrogenases in Japanese quail, Coturnix coturnix japonica. I. Multiple components and some enzymatic properties of nicotinamide adenine dinucleotide-linked L-glycerol-3-phosphate dehydrogenase from liver and testes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346261"}
{"pmid": "4346262", "title": "The purification and properties of geranylgeranyl pyrophosphate synthetase from pumpkin fruit.", "content": "The purification and properties of geranylgeranyl pyrophosphate synthetase from pumpkin fruit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346262"}
{"pmid": "4346263", "title": "Vertebrate collagenase: direct extraction from animal skin and human synovial membrane.", "content": "Vertebrate collagenase: direct extraction from animal skin and human synovial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346263"}
{"pmid": "4346265", "title": "Studies on N-Acetyl- -D-glucosaminidase of Aspergillus oryzae. 3. Transglycosylation by the enzyme and preparation of crystalline phenyl N, N'-diacetyl- -chitobioside.", "content": "Studies on N-Acetyl- -D-glucosaminidase of Aspergillus oryzae. 3. Transglycosylation by the enzyme and preparation of crystalline phenyl N, N'-diacetyl- -chitobioside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346265"}
{"pmid": "4346264", "title": "Reconstitution of hepatic microsomal stearoyl-coenzyme A desaturase system from solubilized components.", "content": "Reconstitution of hepatic microsomal stearoyl-coenzyme A desaturase system from solubilized components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346264"}
{"pmid": "4346266", "title": "Acetanilide-hydrolyzing esterase of rat liver microsomes. I. Solubilization, purification, and intramicrosomal localization.", "content": "Acetanilide-hydrolyzing esterase of rat liver microsomes. I. Solubilization, purification, and intramicrosomal localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346266"}
{"pmid": "4346267", "title": "Enzyme kinetics and its relevance to enzyme assay.", "content": "Enzyme kinetics and its relevance to enzyme assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346267"}
{"pmid": "4346259", "title": "A simple interferon assay as an adjunct for determining the genus of origin of cell cultures.", "content": "A simple interferon assay as an adjunct for determining the genus of origin of cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346259"}
{"pmid": "4346258", "title": "Dissociation of single cells from lung or kidney tissue with elastase.", "content": "Dissociation of single cells from lung or kidney tissue with elastase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346258"}
{"pmid": "4346269", "title": "The effect of neonatal and adult thymectomy on the inflammatory response.", "content": "The effect of neonatal and adult thymectomy on the inflammatory response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346269"}
{"pmid": "4346270", "title": "The digestion of cellular fragments within phagolysosomes in carcinoma cells.", "content": "The digestion of cellular fragments within phagolysosomes in carcinoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346270"}
{"pmid": "4346271", "title": "A comparative histochemical study of rat livers in alpha-naphthyl-iso-thiocyanate (ANIT) and DL-ethionine intoxication.", "content": "A comparative histochemical study of rat livers in alpha-naphthyl-iso-thiocyanate (ANIT) and DL-ethionine intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346271"}
{"pmid": "4346272", "title": "Prostaglandins and reproduction.", "content": "Prostaglandins and reproduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346272"}
{"pmid": "4346273", "title": "Multilocular renal cystic disease in children.", "content": "Multilocular renal cystic disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346273"}
{"pmid": "4346274", "title": "An approach to metastatic nephroblastoma.", "content": "An approach to metastatic nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346274"}
{"pmid": "4346275", "title": "The radiologic discrimination of abdominal masses in infants.", "content": "The radiologic discrimination of abdominal masses in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346275"}
{"pmid": "4346276", "title": "Localization of adrenal tumors by photoscanning.", "content": "Localization of adrenal tumors by photoscanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346276"}
{"pmid": "4346277", "title": "Aspects of the encapsidation of simian virus 40 deoxyribonucleic acid.", "content": "Aspects of the encapsidation of simian virus 40 deoxyribonucleic acid. Growing subcloned CV1-cells were infected with simian virus 40, and the time course of virus formation was determined. When infected cells were fractionated into cytoplasmic and nuclear fractions, most of the progeny virus particles were recovered in the cytoplasmic extract and not in the nuclei. This result was independent of the technique used for the preparation of nuclei and of the time after infection at which the extracts were prepared. Leakage of the virions from the nucleus occurred during the course of cell fractionation, suggesting that the nuclear membrane of the infected cells is damaged. Virions were found to accumulate in a nonlinear fashion, at the time when the number of viral deoxyribonucleic acid (DNA) molecules increases linearly with time after infection. This suggests that the size of the intracellular pool of capsid proteins increases constantly during the late phase of virus replication. Progeny viral DNA to become encapsidated is withdrawn at random from the pool of replicated DNA molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346277"}
{"pmid": "4346278", "title": "Viruses of Entamoeba histolytica. 3. Properties of the polyhedral virus of the HB-301 strain.", "content": "Viruses of Entamoeba histolytica. 3. Properties of the polyhedral virus of the HB-301 strain. Some biological characteristics and bioassay of a polyhedral virus isolated from normal-appearing strain HB-301 of Entamoeba histolytica are described. The virus produced lysis of susceptible strains of E. histolytica, yet it caused no cytopathological effect in the host strain, HB-301. The virus and host amoeba existed in an equilibrium; approximately 10(4) mean infective dose units of virus were produced per million HB-301 amoebae. Superinfection and antiviral antiserum treatment failed to disturb this equilibrium permanently. The mechanism of viral persistence in strain HB-301 amoebae remains to be determined. Purification of the virus was attempted. Ninety-nine percent of the viral infectivity was associated with a low-speed pellet which consisted of complexes of virus and cellular membranes. Various treatments of this low-speed pellet failed to release virus. Biologically active, membrane-free virus of low titer was prepared by differential centrifugation of supernatant solutions and employed in electron microscopy and other studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346278"}
{"pmid": "4346279", "title": "Molecular weights of vesicular stomatitis virus and its defective particles by laser light-scattering spectroscopy.", "content": "Molecular weights of vesicular stomatitis virus and its defective particles by laser light-scattering spectroscopy. Laser light-scattering spectroscopy has been used to determine the diffusion coefficients of vesicular stomatitis virus and three of its defective particles in order to calculate their molecular weights.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346279"}
{"pmid": "4346280", "title": "Replication of the Moloney murine sarcoma-leukemia virus in XC cells.", "content": "Replication of the Moloney murine sarcoma-leukemia virus in XC cells. The XC rat cell line was found to support the replication of a strain of the Moloney murine sarcoma-leukemia virus. In growth curve experiments cytopathology was paralleled by the production of murine sarcoma virus and leukemia virus progeny having the biologic, antigenic, and biophysical properties of the infecting virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346280"}
{"pmid": "4346281", "title": "Patterns of simian virus 40 deoxyribonucleic acid transcription. II. In transformed cells.", "content": "Patterns of simian virus 40 deoxyribonucleic acid transcription. II. In transformed cells. The pattern of simian virus 40 (SV40) deoxyribonucleic acid transcription has been examined in 11 SV40-transformed cell lines. In all cases, substantial regions of the minus strand (35-75%) appeared to be transcribed. In the lines tested, these regions included the \"early\" gene sequences. The SV40-specific ribonucleic acid from at least two of the transformed cell lines represented significantly greater portions of the minus strand than are represented in \"early\" lytic ribonucleic acid. Small regions of the plus strand appeared to be transcribed in only two of the transformed cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346281"}
{"pmid": "4346283", "title": "Oral contraceptives and breast histology.", "content": "Oral contraceptives and breast histology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346283"}
{"pmid": "4346282", "title": "Replication of simian virus 40 deoxyribonucleic acid: analysis of the one-step growth cycle.", "content": "Replication of simian virus 40 deoxyribonucleic acid: analysis of the one-step growth cycle. The time course of replication of simian virus 40 deoxyribonucleic acid (DNA) was investigated in growing monolayer cultures of subcloned CV1 cells. At multiplicities of infection of 30 to 60 plaque-forming units (PFU)/cell, first progeny DNA molecules (component 1) were detected by 10 hr after infection. During the following 10 to 12 hr, accumulation of virus DNA proceeded at ever increasing rates, albeit in a non-exponential fashion. The rate of synthesis then remained constant, until approximately the 40th hour postinfection, when DNA replication stopped. Under these conditions, the duration of the virus growth cycle was approximately 50 hr. The time needed for the synthesis of one DNA molecule was found to be approximately 15 min. At multiplicities of infection of 1 or less than 1 PFU/cell, the onset of the linear phase of DNA accumulation was delayed, but the final rate of DNA synthesis was the same, independent of the input multiplicity. This was taken as a proof that templates for the synthesis of viral DNA multiply in the cell during the early phase of replication. However, the probability for every replicated DNA molecule to become in turn replicative decreased constantly during that phase. This could be accounted for by assuming a limited number of replication sites in the infected cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346282"}
{"pmid": "4346287", "title": "Denmark's geriatric patients: community care and after-care.", "content": "Denmark's geriatric patients: community care and after-care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346287"}
{"pmid": "4346288", "title": "I-cell disease: biochemical studies.", "content": "I-cell disease: biochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346288"}
{"pmid": "4346292", "title": "A case of encephalopathic, myelopathic, and peripheral nerve dysfunction in folate deficient megaloblastic anemia.", "content": "A case of encephalopathic, myelopathic, and peripheral nerve dysfunction in folate deficient megaloblastic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346292"}
{"pmid": "4346293", "title": "Mycoplasma species in association with feline viruses.", "content": "Mycoplasma species in association with feline viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346293"}
{"pmid": "4346294", "title": "Studies of the mechanism of induction of infectious murine leukemia virus from AKR mouse embryo cell lines by 5-iododeoxyuridine and 5-bromodeoxyuridine.", "content": "Studies of the mechanism of induction of infectious murine leukemia virus from AKR mouse embryo cell lines by 5-iododeoxyuridine and 5-bromodeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346294"}
{"pmid": "4346295", "title": "The induction of interferon by temperature-sensitive mutants of reovirus, UV-irradiated reovirus, and subviral reovirus particles.", "content": "The induction of interferon by temperature-sensitive mutants of reovirus, UV-irradiated reovirus, and subviral reovirus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346295"}
{"pmid": "4346296", "title": "Enucleation of cells made simple and rescue of SV40 by enucleated cells made even simpler.", "content": "Enucleation of cells made simple and rescue of SV40 by enucleated cells made even simpler.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346296"}
{"pmid": "4346297", "title": "The effect of dibutyryl cyclic AMP on transformation by oncogenic viruses.", "content": "The effect of dibutyryl cyclic AMP on transformation by oncogenic viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346297"}
{"pmid": "4346298", "title": "Isolation of leukosis-type virus from pheasant embryo cells: possible presence of viral genes in cells.", "content": "Isolation of leukosis-type virus from pheasant embryo cells: possible presence of viral genes in cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346298"}
{"pmid": "4346299", "title": "Characterization of the SV40 T antigen.", "content": "Characterization of the SV40 T antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346299"}
{"pmid": "4346303", "title": "Effects of aircraft noise on human sleep.", "content": "Effects of aircraft noise on human sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346303"}
{"pmid": "4346304", "title": "Active transport of calcium ion in sarcoplasmic membranes.", "content": "Active transport of calcium ion in sarcoplasmic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346304"}
{"pmid": "4346305", "title": "Linear analysis of the dynamics of neural masses.", "content": "Linear analysis of the dynamics of neural masses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346305"}
{"pmid": "4346306", "title": "The mechanism of signal transmission in nerve axons.", "content": "The mechanism of signal transmission in nerve axons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346306"}
{"pmid": "4346307", "title": "Plasticity of biological membranes.", "content": "Plasticity of biological membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346307"}
{"pmid": "4346309", "title": "Isolation and characterization of agglutinin receptor sites. 3. Studies on the interaction with other lectins.", "content": "Isolation and characterization of agglutinin receptor sites. 3. Studies on the interaction with other lectins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346309"}
{"pmid": "4346310", "title": "The interaction of a lytic peptide, melittin, with spin-labeled membranes.", "content": "The interaction of a lytic peptide, melittin, with spin-labeled membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346310"}
{"pmid": "4346311", "title": "Binding and aggregate formation of phospholipid liposomes containing phosphatidic acid with ovalbumin.", "content": "Binding and aggregate formation of phospholipid liposomes containing phosphatidic acid with ovalbumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346311"}
{"pmid": "4346312", "title": "Turnover of rat liver plasma membrane phospholipids comparison with microsomal membranes.", "content": "Turnover of rat liver plasma membrane phospholipids comparison with microsomal membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346312"}
{"pmid": "4346313", "title": "Subcellular fractionation of human lymphocytes. Isolation of two plasma membrane fractions and comparison of the protein components of the various lymphocytic organelles.", "content": "Subcellular fractionation of human lymphocytes. Isolation of two plasma membrane fractions and comparison of the protein components of the various lymphocytic organelles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346313"}
{"pmid": "4346315", "title": "Herpes zoster of the vulva.", "content": "Herpes zoster of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346315"}
{"pmid": "4346316", "title": "Effect of systemic maternal virus infections on the fetus and newborn.", "content": "Effect of systemic maternal virus infections on the fetus and newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346316"}
{"pmid": "4346314", "title": "Immunity of Epstein-Barr virus in Hodgkin's disease preceded by infectious mononucleosis.", "content": "Immunity of Epstein-Barr virus in Hodgkin's disease preceded by infectious mononucleosis. A patient who developed Hodgkin's disease four years after infectious mononucleosis had elevated serum antibody titres to Epstein-Barr virus and delayed hypersensitivity reactions to membrane antigens prepared from fresh autologous spleen, from spleen cells of another Hodgkin's patient, and from cell lines known to carry the Epstein-Barr virus genome. Additional studies in more lymphoma patients will be needed to determine the significance of the reactivity against tumour and virus-associated antigens which has been documented in this patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346314"}
{"pmid": "4346317", "title": "The laboratory diagnosis of virus infections in gynecology and obstetrics.", "content": "The laboratory diagnosis of virus infections in gynecology and obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346317"}
{"pmid": "4346318", "title": "Herpes genitalis: clinical features.", "content": "Herpes genitalis: clinical features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346318"}
{"pmid": "4346319", "title": "Herpes genitalis: venereal aspects.", "content": "Herpes genitalis: venereal aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346319"}
{"pmid": "4346320", "title": "Relation of herpesvirus type 2 to carcinoma of the cervix.", "content": "Relation of herpesvirus type 2 to carcinoma of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346320"}
{"pmid": "4346321", "title": "Significance of herpes simplex virus infection during pregnancy.", "content": "Significance of herpes simplex virus infection during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346321"}
{"pmid": "4346322", "title": "Herpes genitalis: management--present and predicted.", "content": "Herpes genitalis: management--present and predicted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346322"}
{"pmid": "4346323", "title": "Cytomegalovirus infections in the pregnant female and the newborn infant.", "content": "Cytomegalovirus infections in the pregnant female and the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346323"}
{"pmid": "4346325", "title": "Membrane components and enzymes in virally transformed cells.", "content": "Membrane components and enzymes in virally transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346325"}
{"pmid": "4346326", "title": "Surface glycoproteins of cells before and after transformation by oncogenic viruses.", "content": "Surface glycoproteins of cells before and after transformation by oncogenic viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346326"}
{"pmid": "4346328", "title": "Surface changes in transformed cells detected by lectins.", "content": "Surface changes in transformed cells detected by lectins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346328"}
{"pmid": "4346327", "title": "Glycolipid synthesis and tumorigenicity of clones isolated from the Nil 2 line of hamster embryo fibroblasts.", "content": "Glycolipid synthesis and tumorigenicity of clones isolated from the Nil 2 line of hamster embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346327"}
{"pmid": "4346329", "title": "Studies on the specificity of the radio-bioassay for corticotrophin.", "content": "Studies on the specificity of the radio-bioassay for corticotrophin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346329"}
{"pmid": "4346330", "title": "Adrenocorticotropic activity in vitro of the chick embryo pituitary gland.", "content": "Adrenocorticotropic activity in vitro of the chick embryo pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346330"}
{"pmid": "4346331", "title": "The mechanism of cell fusion. II. Formation of chicken erythrocyte polykaryons.", "content": "The mechanism of cell fusion. II. Formation of chicken erythrocyte polykaryons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346331"}
{"pmid": "4346332", "title": "Purification and properties of a protein kinase from bovine corpus luteum that is stimulated by cyclic adenosine 3',5'-monophosphate and luteinizing hormone.", "content": "Purification and properties of a protein kinase from bovine corpus luteum that is stimulated by cyclic adenosine 3',5'-monophosphate and luteinizing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346332"}
{"pmid": "4346333", "title": "New complexes of peroxidases with hydroxamic acids, hydrazides, and amides.", "content": "New complexes of peroxidases with hydroxamic acids, hydrazides, and amides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346333"}
{"pmid": "4346334", "title": "Regulation of biodegradative threonine deaminase. I. Allosteric inhibition of the enzyme by a reaction product and its reversal by adenosin 5'-monophosphate.", "content": "Regulation of biodegradative threonine deaminase. I. Allosteric inhibition of the enzyme by a reaction product and its reversal by adenosin 5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346334"}
{"pmid": "4346335", "title": "Kinetics of electron transfer between cardiac cytochrome c 1  and c.", "content": "Kinetics of electron transfer between cardiac cytochrome c 1  and c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346335"}
{"pmid": "4346336", "title": "Studies on heart phosphofructokinase. Role of fructose 1,6-diphosphate in enzyme activity.", "content": "Studies on heart phosphofructokinase. Role of fructose 1,6-diphosphate in enzyme activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346336"}
{"pmid": "4346337", "title": "Purification and properties of the protein activator of bovine heart cyclic adenosine 3',5'-monophosphate phosphodiesterase.", "content": "Purification and properties of the protein activator of bovine heart cyclic adenosine 3',5'-monophosphate phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346337"}
{"pmid": "4346338", "title": "Light-stimulated phosphorylation of bovine visual pigments by adenosine triphosphate.", "content": "Light-stimulated phosphorylation of bovine visual pigments by adenosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346338"}
{"pmid": "4346339", "title": "A novel sialic acid and fucose-containing disaccharide isolated from the jelly coat of sea urchin eggs.", "content": "A novel sialic acid and fucose-containing disaccharide isolated from the jelly coat of sea urchin eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346339"}
{"pmid": "4346340", "title": "Spectroscopic evidence for a difference between the iron-binding sites of conalbumin.", "content": "Spectroscopic evidence for a difference between the iron-binding sites of conalbumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346340"}
{"pmid": "4346341", "title": "The elongation factor 2 content of mammalian cells. Assay method and relation to ribosome number.", "content": "The elongation factor 2 content of mammalian cells. Assay method and relation to ribosome number.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346341"}
{"pmid": "4346342", "title": "Mammalian deoxyribonucleic acid ligase. Isolation of an active enzyme-adenylate complex.", "content": "Mammalian deoxyribonucleic acid ligase. Isolation of an active enzyme-adenylate complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346342"}
{"pmid": "4346343", "title": "Binding of testosterone to uterine components of the immature rat.", "content": "Binding of testosterone to uterine components of the immature rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346343"}
{"pmid": "4346344", "title": "Regulation and mechanism of phosphoribosylpyrophosphate synthetase. V. Inhibition by end products and regulation by adenosine diphosphate.", "content": "Regulation and mechanism of phosphoribosylpyrophosphate synthetase. V. Inhibition by end products and regulation by adenosine diphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346344"}
{"pmid": "4346345", "title": "Evidence against two \"pH locked\" conformations of phosphorylated trypsin.", "content": "Evidence against two \"pH locked\" conformations of phosphorylated trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346345"}
{"pmid": "4346346", "title": "Activation of muscle fructose 1,6-diphosphatase by creatine phosphate and citrate.", "content": "Activation of muscle fructose 1,6-diphosphatase by creatine phosphate and citrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346346"}
{"pmid": "4346347", "title": "Electron spin resonance of  63 Cu and  65 Cu carbonic anhydrases. Resolution of nitrogen ligand superhyperfine structure.", "content": "Electron spin resonance of  63 Cu and  65 Cu carbonic anhydrases. Resolution of nitrogen ligand superhyperfine structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346347"}
{"pmid": "4346348", "title": "Gluconeogenesis in rabbit liver. I. Pyruvate-derived dicarboxylic acids and phosphoenolpyruvate formation in rabbit liver.", "content": "Gluconeogenesis in rabbit liver. I. Pyruvate-derived dicarboxylic acids and phosphoenolpyruvate formation in rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346348"}
{"pmid": "4346349", "title": "Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. 8. Monovalent cation sites regulating phosphatase activity.", "content": "Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. 8. Monovalent cation sites regulating phosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346349"}
{"pmid": "4346350", "title": "A form of reduced nicotinamide adenine dinucleotide-cytochrome b 5   reductase containing both the catalytic site and an additional hydrophobic membrane-binding segment.", "content": "A form of reduced nicotinamide adenine dinucleotide-cytochrome b 5   reductase containing both the catalytic site and an additional hydrophobic membrane-binding segment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346350"}
{"pmid": "4346351", "title": "Lipid-protein interactions in the reconstitution of the microsomal reduced nicotinamide adenine dinucleotide-cytochrome b 5  reductase system.", "content": "Lipid-protein interactions in the reconstitution of the microsomal reduced nicotinamide adenine dinucleotide-cytochrome b 5  reductase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346351"}
{"pmid": "4346352", "title": "Anomalous ligand binding by a class of high spin c-type cytochromes.", "content": "Anomalous ligand binding by a class of high spin c-type cytochromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346352"}
{"pmid": "4346353", "title": "Adrenal gland in vitamin E deficiency. 3. Inhibition of adrenocorticotropic hormone-induced steroidogenesis in isolated adrenal cells by ascorbic acid.", "content": "Adrenal gland in vitamin E deficiency. 3. Inhibition of adrenocorticotropic hormone-induced steroidogenesis in isolated adrenal cells by ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346353"}
{"pmid": "4346354", "title": "Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. I. Formation of cyclic adenosine 3',5'-monophosphate from endogenous adenosine triphosphate and from radioactive adenosine triphosphate formed during a prior incubation with radioactive adenine.", "content": "Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. I. Formation of cyclic adenosine 3',5'-monophosphate from endogenous adenosine triphosphate and from radioactive adenosine triphosphate formed during a prior incubation with radioactive adenine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346354"}
{"pmid": "4346356", "title": "Properties of adenosine 3',5'-monophosphate-dependent protein kinases isolated from bovine epididymal spermatozoa.", "content": "Properties of adenosine 3',5'-monophosphate-dependent protein kinases isolated from bovine epididymal spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346356"}
{"pmid": "4346355", "title": "Sodium-potassium-activated adenosine triphosphatase. IX. The role of phospholipids.", "content": "Sodium-potassium-activated adenosine triphosphatase. IX. The role of phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346355"}
{"pmid": "4346357", "title": "Chemical sympathectomy and avoidance learning in the rat.", "content": "Chemical sympathectomy and avoidance learning in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346357"}
{"pmid": "4346358", "title": "Femoral neuropathy due to haemorrhage into iliacus muscle.", "content": "Femoral neuropathy due to haemorrhage into iliacus muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346358"}
{"pmid": "4346359", "title": "Plasma cortisol.", "content": "Plasma cortisol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346359"}
{"pmid": "4346361", "title": "A clinicopathological study of synovial sarcoma.", "content": "A clinicopathological study of synovial sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346361"}
{"pmid": "4346360", "title": "Plasma cortisol level in normal Indian subjects and its variation in disease.", "content": "Plasma cortisol level in normal Indian subjects and its variation in disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346360"}
{"pmid": "4346364", "title": "The angiographic appearance of nasopharyngeal carcinoma.", "content": "The angiographic appearance of nasopharyngeal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346364"}
{"pmid": "4346365", "title": "Studies on the adrenocortical hormone therapy in idiopathic nephrotic syndrome in children.", "content": "Studies on the adrenocortical hormone therapy in idiopathic nephrotic syndrome in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346365"}
{"pmid": "4346368", "title": "Radioimmunoassay of angiotensin and determination of renin activity.", "content": "Radioimmunoassay of angiotensin and determination of renin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346368"}
{"pmid": "4346367", "title": "Principles of brain scan interpretation.", "content": "Principles of brain scan interpretation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346367"}
{"pmid": "4346369", "title": "Selective angiography in localizing islet-cell tumors of the pancreas. A further appraisal.", "content": "Selective angiography in localizing islet-cell tumors of the pancreas. A further appraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346369"}
{"pmid": "4346370", "title": "Parasitic blood supply of neoplasms. Mechanisms and significance.", "content": "Parasitic blood supply of neoplasms. Mechanisms and significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346370"}
{"pmid": "4346371", "title": "Arteriographic findings in synovial hemangioma of the knee.", "content": "Arteriographic findings in synovial hemangioma of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346371"}
{"pmid": "4346372", "title": "Multilocular cyst of the kidney. A case report with angiographic findings.", "content": "Multilocular cyst of the kidney. A case report with angiographic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346372"}
{"pmid": "4346373", "title": "Radiotherapy in chest malignant tumors associated with pulmonary tuberculosis.", "content": "Radiotherapy in chest malignant tumors associated with pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346373"}
{"pmid": "4346374", "title": "Massive hemoperitoneum from rupture of benign hepatocellular adenoma.", "content": "Massive hemoperitoneum from rupture of benign hepatocellular adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346374"}
{"pmid": "4346379", "title": "Changes of immunologic competence of lymphocytes evaluated by phytohemagglutinin (PHA)-induced DNA synthesis related to pregnancy and gynecologic tumors.", "content": "Changes of immunologic competence of lymphocytes evaluated by phytohemagglutinin (PHA)-induced DNA synthesis related to pregnancy and gynecologic tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346379"}
{"pmid": "4346380", "title": "Establishment of Entamoeba histolytica from liver abscess in monoxenic cultures with hemoflagellates.", "content": "Establishment of Entamoeba histolytica from liver abscess in monoxenic cultures with hemoflagellates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346380"}
{"pmid": "4346381", "title": "Herpes zoster dendritic keratitis.", "content": "Herpes zoster dendritic keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346381"}
{"pmid": "4346382", "title": "Radiation therapy of glomus jugulare tumors.", "content": "Radiation therapy of glomus jugulare tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346382"}
{"pmid": "4346383", "title": "Long-term results of therapy of glomus jugulare tumors.", "content": "Long-term results of therapy of glomus jugulare tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346383"}
{"pmid": "4346384", "title": "Brain microsomal protein kinase in the chronically morphinized rat.", "content": "Brain microsomal protein kinase in the chronically morphinized rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346384"}
{"pmid": "4346385", "title": "Accelerated turnover rate of nicotinamide-adenine dinucleotides in the liver of rats intoxicated with carbon disulphide.", "content": "Accelerated turnover rate of nicotinamide-adenine dinucleotides in the liver of rats intoxicated with carbon disulphide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346385"}
{"pmid": "4346386", "title": "Effects of tubercidin and its ribonucleotides on various metabolic pathways in Schistosoma mansoni.", "content": "Effects of tubercidin and its ribonucleotides on various metabolic pathways in Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346386"}
{"pmid": "4346387", "title": "Kininase activity in equine plasma.", "content": "Kininase activity in equine plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346387"}
{"pmid": "4346388", "title": "Reducibility of cytochromes b in aerobic beef-heart mitochondria treated with antimycin.", "content": "Reducibility of cytochromes b in aerobic beef-heart mitochondria treated with antimycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346388"}
{"pmid": "4346389", "title": "Oxidoreduction of cytochrome b in the presence of antimycin.", "content": "Oxidoreduction of cytochrome b in the presence of antimycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346389"}
{"pmid": "4346390", "title": "Quantitative EPR studies of the primary reaction of photosystem I in chloroplasts.", "content": "Quantitative EPR studies of the primary reaction of photosystem I in chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346390"}
{"pmid": "4346391", "title": "The reduction mechanism of ferricytochrome c.", "content": "The reduction mechanism of ferricytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346391"}
{"pmid": "4346419", "title": "Factors influencing induction and duration of oculomotor reflex rebound in the guinea pig.", "content": "Factors influencing induction and duration of oculomotor reflex rebound in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346419"}
{"pmid": "4346417", "title": "Further enzyme histochemical observations on the segmentation of the proximal tubules in the kidney of the male rat.", "content": "Further enzyme histochemical observations on the segmentation of the proximal tubules in the kidney of the male rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346417"}
{"pmid": "4346421", "title": "Granular cell myoblastoma of the bronchus. Report of two cases, one diagnosed by exfoliative cytology.", "content": "Granular cell myoblastoma of the bronchus. Report of two cases, one diagnosed by exfoliative cytology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346421"}
{"pmid": "4346420", "title": "Effect of dexamethasone on affective behavior and adrenal reactivity following septal lesions in the rat.", "content": "Effect of dexamethasone on affective behavior and adrenal reactivity following septal lesions in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346420"}
{"pmid": "4346422", "title": "Activity of plasma angiotensin II in experimental coarctation of the aorta.", "content": "Activity of plasma angiotensin II in experimental coarctation of the aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346422"}
{"pmid": "4346428", "title": "Quantitation of RNA tumor viruses and viruslike particles in human milk by hybridization to polyadenylic acid sequences.", "content": "Quantitation of RNA tumor viruses and viruslike particles in human milk by hybridization to polyadenylic acid sequences. RNA tumor viruses and viruslike particles from human milk are quantitated by hybridization of the polyadenylic acid regions in their 60S to 70S RNA to radioactive polyribouridylic acid of known specific activity. The length of the polyadenylic acid region in the 60S to 70S RNA of the human milk particle is identical to that of the known oncogenic RNA viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346428"}
{"pmid": "4346427", "title": "Activities of certain enzymes of glycolytic pathway in normal, chronic cervicitis and malignant human cervix uteri.", "content": "Activities of certain enzymes of glycolytic pathway in normal, chronic cervicitis and malignant human cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346427"}
{"pmid": "4346431", "title": "Recovery of infectious canine hepatitis virus from dogs with different clinical syndromes.", "content": "Recovery of infectious canine hepatitis virus from dogs with different clinical syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346431"}
{"pmid": "4346432", "title": "Review of canine viral disease.", "content": "Review of canine viral disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346432"}
{"pmid": "4346433", "title": "Studies on the reconstituion of bovine erythrocyte superoxide dismutase. 3. Evidence for a strong interdependence between Cu 2+  and Zn 2+  binding in the expression of the spectroscopic properties of the native protein and for a close proximity of the Zn 2+  and Cu 2+  sites.", "content": "Studies on the reconstituion of bovine erythrocyte superoxide dismutase. 3. Evidence for a strong interdependence between Cu 2+  and Zn 2+  binding in the expression of the spectroscopic properties of the native protein and for a close proximity of the Zn 2+  and Cu 2+  sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346433"}
{"pmid": "4346435", "title": "The isolation and properties of pig plasma lipoproteins and partial characterisation of their apoproteins.", "content": "The isolation and properties of pig plasma lipoproteins and partial characterisation of their apoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346435"}
{"pmid": "4346434", "title": "On the physiological role of   2 -macroglobulin.", "content": "On the physiological role of   2 -macroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346434"}
{"pmid": "4346436", "title": "Evidence for intramolecular crosslinks in chicken bone collagen: the isolation of peptides containing allysine aldol.", "content": "Evidence for intramolecular crosslinks in chicken bone collagen: the isolation of peptides containing allysine aldol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346436"}
{"pmid": "4346437", "title": "Environment of the iron-sulfur chromophore in adrenodoxin studied by EPR and ENDOR spectroscopy.", "content": "Environment of the iron-sulfur chromophore in adrenodoxin studied by EPR and ENDOR spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346437"}
{"pmid": "4346438", "title": "Studies on the reconstitution of bovine erythrocyte superoxide dismutase. I. The presence of four divalent metal-binding sites on the apo protein which are different from the native sites.", "content": "Studies on the reconstitution of bovine erythrocyte superoxide dismutase. I. The presence of four divalent metal-binding sites on the apo protein which are different from the native sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346438"}
{"pmid": "4346439", "title": "Interactions of bovine serum albumin with penicillins and cephalosporins studied by pulse radiolysis.", "content": "Interactions of bovine serum albumin with penicillins and cephalosporins studied by pulse radiolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346439"}
{"pmid": "4346441", "title": "Synaptic transmission in the submandibular ganglion of the rat.", "content": "Synaptic transmission in the submandibular ganglion of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346441"}
{"pmid": "4346440", "title": "Studies on the reconstitution of bovine erythrocyte superoxide dismutase. II. Some observations on the nature of catalyzed superoxide anion dismutation as an enzymatic activity.", "content": "Studies on the reconstitution of bovine erythrocyte superoxide dismutase. II. Some observations on the nature of catalyzed superoxide anion dismutation as an enzymatic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346440"}
{"pmid": "4346447", "title": "Areexamination of phase IV Bordetella pertussis.", "content": "Areexamination of phase IV Bordetella pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346447"}
{"pmid": "4346448", "title": "Ultrastructure of Filobasidium Olive.", "content": "Ultrastructure of Filobasidium Olive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346448"}
{"pmid": "4346449", "title": "Growth and ultrastructural differentiation of sporangia in Phytophthora palmivora.", "content": "Growth and ultrastructural differentiation of sporangia in Phytophthora palmivora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346449"}
{"pmid": "4346453", "title": "Effect of some adenosine 3',5'-monophosphate analogues on cell proliferation, tumor growth and macromolecular synthesis in various organs of the mouse.", "content": "Effect of some adenosine 3',5'-monophosphate analogues on cell proliferation, tumor growth and macromolecular synthesis in various organs of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346453"}
{"pmid": "4346467", "title": "Modification of yeast tyrosine tRNA with N-acetoxy-2-acetylaminofluorene.", "content": "Modification of yeast tyrosine tRNA with N-acetoxy-2-acetylaminofluorene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346467"}
{"pmid": "4346468", "title": "The conversion of ornithine to proline: compartmentation of enzymes between cytoplasm and mitochondria.", "content": "The conversion of ornithine to proline: compartmentation of enzymes between cytoplasm and mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346468"}
{"pmid": "4346471", "title": "Multiple steroid hormone receptors in calf uterus. Binding specificities and distribution.", "content": "Multiple steroid hormone receptors in calf uterus. Binding specificities and distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346471"}
{"pmid": "4346473", "title": "Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent.", "content": "Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. As a highly reactive substance produced in biological systems by the one-electron reduction of oxygen, superoxide (O(2) (-)) seemed a likely candidate as a bactericidal agent in leukocytes. The reduction of cytochrome c, a process in which O(2) (-) may serve as an electron donor, was found to occur when the cytochrome was incubated with leukocytes. O(2) (-) was identified as the agent responsible for the leukocyte-mediated reduction of cytochrome c by the demonstration that the reaction was abolished by superoxide dismutase, an enzyme that destroys O(2) (-), but not by boiled dismutase, albumin, or catalase. Leukocyte O(2) (-) production doubled in the presence of latex particles. The average rate of formation of O(2) (-) in the presence of these particles was 1.03 nmol/10(7) cells per 15 min. This rate, however, is only a lower limit of the true rate of O(2) (-) production, since any O(2) (-) which reacted with constituents other than cytochrome c would have gone undetected. Thus. O(2) (-) is made by leukocytes under circumstances which suggest that it may be involved in bacterial killing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346473"}
{"pmid": "4346472", "title": "Activity of some actinomycetes and high plants against foot and mouth disease virus.", "content": "Activity of some actinomycetes and high plants against foot and mouth disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346472"}
{"pmid": "4346496", "title": "Measles giant cell pneumonia without rash in a case of lymphocytic lymphosarcoma. An electron microscopic study.", "content": "Measles giant cell pneumonia without rash in a case of lymphocytic lymphosarcoma. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346496"}
{"pmid": "4346500", "title": "Ultimobranchial gland ultrastructure of larval axolotls, Ambystoma mexicanum Shaw, with some observations on the newt, Pleurodeles waltlii Micahelles.", "content": "Ultimobranchial gland ultrastructure of larval axolotls, Ambystoma mexicanum Shaw, with some observations on the newt, Pleurodeles waltlii Micahelles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346500"}
{"pmid": "4346502", "title": "Ultrastructural studies on the hypothalamic neurosecretory neurons of the rat. II. The hypothalamo-neurohypophysial system in rats with hereditary hypothalamic diabetes insipidus.", "content": "Ultrastructural studies on the hypothalamic neurosecretory neurons of the rat. II. The hypothalamo-neurohypophysial system in rats with hereditary hypothalamic diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346502"}
{"pmid": "4346504", "title": "Ultrastructure of the hepatopancreas and associated tissues of the chelicerate arthropod, Limulus polyphemus.", "content": "Ultrastructure of the hepatopancreas and associated tissues of the chelicerate arthropod, Limulus polyphemus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346504"}
{"pmid": "4346505", "title": "Gas secreting cells in the rear chamber of the swimbladder of the pond-loach, Misgurnus fossilis L. An electron microscopic study.", "content": "Gas secreting cells in the rear chamber of the swimbladder of the pond-loach, Misgurnus fossilis L. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346505"}
{"pmid": "4346507", "title": "Disturbance of blood glucose regulation in pertussis sensitized rats.", "content": "Disturbance of blood glucose regulation in pertussis sensitized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346507"}
{"pmid": "4346508", "title": "Semisynthetic penicillins. IX. Thiophene compounds related to oxacillin and cloxacillin.", "content": "Semisynthetic penicillins. IX. Thiophene compounds related to oxacillin and cloxacillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346508"}
{"pmid": "4346509", "title": "The kinin system in allergic states.", "content": "The kinin system in allergic states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346509"}
{"pmid": "4346510", "title": "Primary aldosteronism due to hyperplasia of zona glomerulosa: failure of suppression by DOCA or stimulation by angiotensin.", "content": "Primary aldosteronism due to hyperplasia of zona glomerulosa: failure of suppression by DOCA or stimulation by angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346510"}
{"pmid": "4346511", "title": "Fatal disseminated intravascular coagulation and hemolytic anemia following stibophen therapy: a study of basic mechanisms.", "content": "Fatal disseminated intravascular coagulation and hemolytic anemia following stibophen therapy: a study of basic mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346511"}
{"pmid": "4346514", "title": "The purification and properties of superoxide dismutase from Saccharomyces cerevisiae.", "content": "The purification and properties of superoxide dismutase from Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346514"}
{"pmid": "4346515", "title": "A specific colorimetric and cytochemical substrate for ribonuclease T 2 : adenosine-3'-( -naphtylphosphate).", "content": "A specific colorimetric and cytochemical substrate for ribonuclease T 2 : adenosine-3'-( -naphtylphosphate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346515"}
{"pmid": "4346517", "title": "Inhibitors of the pulmonary angiotensin I-converting enzyme.", "content": "Inhibitors of the pulmonary angiotensin I-converting enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346517"}
{"pmid": "4346516", "title": "Proteolytic enzymes in extracts of Schistosoma mansoni cercariae.", "content": "Proteolytic enzymes in extracts of Schistosoma mansoni cercariae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346516"}
{"pmid": "4346518", "title": "Anomalous kinetics observed in the catalysis of a peptide substrate with collagenase.", "content": "Anomalous kinetics observed in the catalysis of a peptide substrate with collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346518"}
{"pmid": "4346520", "title": "Free radicals in malonic acid: a study of radical conformations at 77K and 295K by the ESR-technique.", "content": "Free radicals in malonic acid: a study of radical conformations at 77K and 295K by the ESR-technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346520"}
{"pmid": "4346519", "title": "Behavior of cycloaldolase from Neurospora crassa towards substrate analogs and aldolase inhibitors.", "content": "Behavior of cycloaldolase from Neurospora crassa towards substrate analogs and aldolase inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346519"}
{"pmid": "4346522", "title": "The energy metabolism of human-blood polymorphonuclear cells. Action of various effectors, except hormones.", "content": "The energy metabolism of human-blood polymorphonuclear cells. Action of various effectors, except hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346522"}
{"pmid": "4346521", "title": "Synthesis and evaluation of the anticancer activity of some water soluble maleimide derivatives.", "content": "Synthesis and evaluation of the anticancer activity of some water soluble maleimide derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346521"}
{"pmid": "4346523", "title": "Conformational isomers of nitrosyl-haemoglobin. An electron-spin-resonance study.", "content": "Conformational isomers of nitrosyl-haemoglobin. An electron-spin-resonance study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346523"}
{"pmid": "4346526", "title": "Histochemical study of TPPase and NDPase in the human nervous tissue, with particular reference to glia cells.", "content": "Histochemical study of TPPase and NDPase in the human nervous tissue, with particular reference to glia cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346526"}
{"pmid": "4346525", "title": "Variation of phosphorylase distribution in skeletal muscles.", "content": "Variation of phosphorylase distribution in skeletal muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346525"}
{"pmid": "4346527", "title": "Microbial and hepatic cuprein (superoxide dismutase). Isolation and characterisation of cuprein (superoxide dismutase) from Saccharomyces cerevisiae and bovine liver.", "content": "Microbial and hepatic cuprein (superoxide dismutase). Isolation and characterisation of cuprein (superoxide dismutase) from Saccharomyces cerevisiae and bovine liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346527"}
{"pmid": "4346528", "title": "Metabolism of pyridine nucleotides and its relation to DNA synthesis in regenerating mouse liver.", "content": "Metabolism of pyridine nucleotides and its relation to DNA synthesis in regenerating mouse liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346528"}
{"pmid": "4346530", "title": "Function of thiol groups in yeast pyruvate kinase.", "content": "Function of thiol groups in yeast pyruvate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346530"}
{"pmid": "4346532", "title": "Comparative thin-layer chromatography of indole-containing metabolites of tryptophan and their sulfur isosteres.", "content": "Comparative thin-layer chromatography of indole-containing metabolites of tryptophan and their sulfur isosteres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346532"}
{"pmid": "4346531", "title": "Disturbance by tumor promotors of epidermal growth control (chalone mechanism).", "content": "Disturbance by tumor promotors of epidermal growth control (chalone mechanism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346531"}
{"pmid": "4346533", "title": "Susceptibility and resistance to viral leukemogenesis in the mouse. IV. Mechanisms of host resistance to leukemia expression.", "content": "Susceptibility and resistance to viral leukemogenesis in the mouse. IV. Mechanisms of host resistance to leukemia expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346533"}
{"pmid": "4346534", "title": "Mechanism of syncytium formation between XC sarcoma cells and murine endocrine carcinoma cells.", "content": "Mechanism of syncytium formation between XC sarcoma cells and murine endocrine carcinoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346534"}
{"pmid": "4346535", "title": "Rabbit kidney vacuolating virus in spontaneous Shope papillomas of cottontail rabbits.", "content": "Rabbit kidney vacuolating virus in spontaneous Shope papillomas of cottontail rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346535"}
{"pmid": "4346537", "title": "Immunologic reactivity of the cat: immunosuppression in experimental feline leukemia.", "content": "Immunologic reactivity of the cat: immunosuppression in experimental feline leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346537"}
{"pmid": "4346536", "title": "Tissue culture studies of mouse mammary tumor cells and associated viruses.", "content": "Tissue culture studies of mouse mammary tumor cells and associated viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346536"}
{"pmid": "4346538", "title": "Virus-like particles in guinea pig oogonia and oocytes.", "content": "Virus-like particles in guinea pig oogonia and oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346538"}
{"pmid": "4346539", "title": "Enhancement of tumor growth rate by interferon inducers.", "content": "Enhancement of tumor growth rate by interferon inducers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346539"}
{"pmid": "4346540", "title": "Precipitating antibody to an internal antigen of the C-type virus associated with bovine lymphosarcoma.", "content": "Precipitating antibody to an internal antigen of the C-type virus associated with bovine lymphosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346540"}
{"pmid": "4346541", "title": "Transmission of lymphosarcoma from cattle to sheep.", "content": "Transmission of lymphosarcoma from cattle to sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346541"}
{"pmid": "4346553", "title": "Fine structure of the autonomic nerves of the rabbit myometrium.", "content": "Fine structure of the autonomic nerves of the rabbit myometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346553"}
{"pmid": "4346552", "title": "Quantitative data on the fine structural organization of the palisade zone of the median eminence.", "content": "Quantitative data on the fine structural organization of the palisade zone of the median eminence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346552"}
{"pmid": "4346556", "title": "A morphologic and histochemical study of biliary atresia in lamprey liver.", "content": "A morphologic and histochemical study of biliary atresia in lamprey liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346556"}
{"pmid": "4346546", "title": "Synthesis of glycogen in leucocytes from various precursors.", "content": "Synthesis of glycogen in leucocytes from various precursors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346546"}
{"pmid": "4346548", "title": "Altered kinetic property of erythrocyte phosphoribosylpsyrophosphate synthetase in excessive purine production.", "content": "Altered kinetic property of erythrocyte phosphoribosylpsyrophosphate synthetase in excessive purine production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346548"}
{"pmid": "4346557", "title": "Corticotrophic cells in the rostral zone of the pars intermedia and in the adjacent neurohypophysis of the rat and mouse. An electron microscopic study.", "content": "Corticotrophic cells in the rostral zone of the pars intermedia and in the adjacent neurohypophysis of the rat and mouse. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346557"}
{"pmid": "4346558", "title": "Ultrastructure of the chick thymus.", "content": "Ultrastructure of the chick thymus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346558"}
{"pmid": "4346559", "title": "Secretory surface phenomena in freeze-etched preparations of the adenohypophysial cells and neurosecretory fibers.", "content": "Secretory surface phenomena in freeze-etched preparations of the adenohypophysial cells and neurosecretory fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346559"}
{"pmid": "4346547", "title": "Renal transplantation and viral infections. I. A retrospective serological study of renal transplantation recipients.", "content": "Renal transplantation and viral infections. I. A retrospective serological study of renal transplantation recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346547"}
{"pmid": "4346561", "title": "The effects of desiccation and starvation upon the weight, histology and ultrastructure of the reproductive tract of Biomphalaria glabrata, intermediate host of Schistosoma mansoni.", "content": "The effects of desiccation and starvation upon the weight, histology and ultrastructure of the reproductive tract of Biomphalaria glabrata, intermediate host of Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346561"}
{"pmid": "4346560", "title": "Histochemical demonstration of delta 5 -3  -OHD activity in the granulosa cells of ovarian follicles of immature and mature mice correlated with some ultrastructural observations.", "content": "Histochemical demonstration of delta 5 -3  -OHD activity in the granulosa cells of ovarian follicles of immature and mature mice correlated with some ultrastructural observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346560"}
{"pmid": "4346562", "title": "Epithelial ultrastructure and the distribution of an estradiol sensitive antigen in the vagina of adult mice.", "content": "Epithelial ultrastructure and the distribution of an estradiol sensitive antigen in the vagina of adult mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346562"}
{"pmid": "4346565", "title": "Effects of pH on the intra- and extramitochondrial nicotinamide adenine dinucleotide systems.", "content": "Effects of pH on the intra- and extramitochondrial nicotinamide adenine dinucleotide systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346565"}
{"pmid": "4346566", "title": "Landlord-supervised cooperative apartments: a new modality for community-based treatment.", "content": "Landlord-supervised cooperative apartments: a new modality for community-based treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346566"}
{"pmid": "4346568", "title": "Quantitative evaluation of normal and pathologic cerebral blood flow regulation to perfusion pressure. Changes in man.", "content": "Quantitative evaluation of normal and pathologic cerebral blood flow regulation to perfusion pressure. Changes in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346568"}
{"pmid": "4346569", "title": "Acute optic neuropathy in older patients.", "content": "Acute optic neuropathy in older patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346569"}
{"pmid": "4346570", "title": "Studies on the mechanism of the antilipolytic effect of Paraoxon.", "content": "Studies on the mechanism of the antilipolytic effect of Paraoxon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346570"}
{"pmid": "4346572", "title": "The acid and alkaline phosphatases, inorganic pyrophosphatases and phosphoprotein phosphatase of bone. II. Distribution in subcellular fractions of bone tissue homogenates and structure-linked latency.", "content": "The acid and alkaline phosphatases, inorganic pyrophosphatases and phosphoprotein phosphatase of bone. II. Distribution in subcellular fractions of bone tissue homogenates and structure-linked latency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346572"}
{"pmid": "4346571", "title": "The acid and alkaline phosphatases, inorganic pyrophosphatases and phosphoprotein phosphatase of bone. I. Characterization and assay.", "content": "The acid and alkaline phosphatases, inorganic pyrophosphatases and phosphoprotein phosphatase of bone. I. Characterization and assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346571"}
{"pmid": "4346573", "title": "Histone hydrolase activity of rat liver lysosomal cathepsin B2.", "content": "Histone hydrolase activity of rat liver lysosomal cathepsin B2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346573"}
{"pmid": "4346574", "title": "The study of natural sleep after general anaesthesia in the cat.", "content": "The study of natural sleep after general anaesthesia in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346574"}
{"pmid": "4346575", "title": "Effect of silica on phospholipids in the rat lung.", "content": "Effect of silica on phospholipids in the rat lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346575"}
{"pmid": "4346576", "title": "Extensive superficial vulvectomy with primary skin grafting for premalignant lesions.", "content": "Extensive superficial vulvectomy with primary skin grafting for premalignant lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346576"}
{"pmid": "4346577", "title": "Herpes hepatitis in adults.", "content": "Herpes hepatitis in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346577"}
{"pmid": "4346578", "title": "Efficacy of whooping-cough vaccines used in the United Kingdom before 1968.", "content": "Efficacy of whooping-cough vaccines used in the United Kingdom before 1968. The efficacy of pertussis vaccines was investigated in 33 areas in the United Kingdom from November 1966 until April 1968 inclusive. Bordetella pertussis was isolated from 1,293 persons, but there were only six isolations of B. papapertussis. Among vaccinated contacts under 5 years in homes in which B. pertussis was isolated 52% developed paroxysmal cough. The corresponding attack rate among unvaccinated contacts was 69%. These findings suggest that much of the pertussis vaccine in use for five or six years before 1968 was not very effective. However, vaccine from one producer was more effective than vaccine from another. Of the cultures of B. pertussis identified 89% were serotype 1, 3 and only about 9% were serotype 1, 2, 3. Serotype 1, 2, 3 was isolated much more frequently from unvaccinated than from vaccinated children, but some cultures identified as type 1, 2, 3 were found on re-examination to contain colonies of type 1, 3. Virological investigations were made in some areas during the first year of the study. Of the wide variety of viruses identified adenovirus and parainfluenza virus were the most common groups. Virus isolation rates were similar in patients and symptomless contacts, but B. pertussis was isolated far more often from patients than from symptomless contacts. The evidence suggests that B. pertussis remained the major cause of whooping cough in the U.K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346578"}
{"pmid": "4346580", "title": "Technique of oil myelography.", "content": "Technique of oil myelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346580"}
{"pmid": "4346581", "title": "Corticosteroid withdrawal in asthma.", "content": "Corticosteroid withdrawal in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346581"}
{"pmid": "4346582", "title": "WHO collaborative studies on poliovirus type 3 strains isolated during the 1968 poliomyelitis epidemic in Poland.", "content": "WHO collaborative studies on poliovirus type 3 strains isolated during the 1968 poliomyelitis epidemic in Poland. In 1968 in Poland an extensive outbreak of poliomyelitis, caused by type 3 poliovirus, began about four months after small vaccine trials with the Leon 12a(1)b (Sabin) and USOL-D bac vaccine strains had been carried out. Because of the temporal association, and because the first cases appeared in the province in which the USOL-D vaccine trial was carried out, a detailed investigation of the strains isolated from cases in the epidemic was made in four laboratories in an attempt to determine whether they were related to the two vaccine strains or to a \"wild\" strain. All the studies were made under code. The rct marker was of no help in determining the relationship of the epidemic strains to the vaccine strains. The McBride test and the elution marker test clearly separated the Leon 12a(1)b strains from those from the cases, but were incapable of detecting whether the epidemic strains were related to the USOL-D bac strain or to wild type 3 strains. Thus the studies did not provide valid information on the origin of the epidemic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346582"}
{"pmid": "4346579", "title": "Comparison of corticotrophin and corticosteroid response to lysine vasopressin, insulin, and pyrogen in man.", "content": "Comparison of corticotrophin and corticosteroid response to lysine vasopressin, insulin, and pyrogen in man. Plasma corticotrophin (ACTH) and corticosteroid levels in response to lysine vasopressin (LVP), insulin hypoglycaemia, and pyrogen have been compared in seven subjects with normal pituitary adrenal function. Intramuscular vasopressin was a weak stimulus to corticotrophin release, peak values lying within the range 49 to 141 pg/ml. Insulin hypoglycaemia consistently caused a more noticeable increase, with peak levels between 114 and 364 pg/ml, while pyrogen was the most powerful, corticotrophin levels rising to between 209 and 1,725 pg/ml. Peak plasma corticosteroid levels showed less pronounced differences between the three tests, and correlated poorly with peak ACTH levels. Thus, relatively small acute changes in corticotrophin levels produce near-maximal adrenal stimulation. Under these conditions, plasma corticosteroid measurements do not accurately reflect circulating corticotrophin levels. These findings help to explain the physiological basis of several observations on the corticosteroid responses to these clinical test procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346579"}
{"pmid": "4346583", "title": "Role of vacuoles and vesicles in extracellular enzyme secretion from yeast.", "content": "Role of vacuoles and vesicles in extracellular enzyme secretion from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346583"}
{"pmid": "4346584", "title": "Studies on cell fusion and the rescue of SV40 from cell cultures of successive generations of C1 2  TSV 5  - and RHaT-produced hamster tumors.", "content": "Studies on cell fusion and the rescue of SV40 from cell cultures of successive generations of C1 2  TSV 5  - and RHaT-produced hamster tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346584"}
{"pmid": "4346585", "title": "Studies on the immunogenicity of virus-infected lymphocytes for the production of antilymphocyte serum.", "content": "Studies on the immunogenicity of virus-infected lymphocytes for the production of antilymphocyte serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346585"}
{"pmid": "4346587", "title": "Characterization of viomycin and its acyl derivatives.", "content": "Characterization of viomycin and its acyl derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346587"}
{"pmid": "4346588", "title": "The total structure of viomycin by sequential analysis.", "content": "The total structure of viomycin by sequential analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346588"}
{"pmid": "4346589", "title": "Studies on steroid conjugates. X. Significance of conjugation involved in biosynthesis of 2-methoxyestrogen.", "content": "Studies on steroid conjugates. X. Significance of conjugation involved in biosynthesis of 2-methoxyestrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346589"}
{"pmid": "4346590", "title": "A new phosphatase produced by Streptomyces yokosukanensis.", "content": "A new phosphatase produced by Streptomyces yokosukanensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346590"}
{"pmid": "4346591", "title": "Modifications in primate cerebral circulation and electrical activity with profound hypothermia.", "content": "Modifications in primate cerebral circulation and electrical activity with profound hypothermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346591"}
{"pmid": "4346592", "title": "Cryoprotection of some rat heart enzymes.", "content": "Cryoprotection of some rat heart enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346592"}
{"pmid": "4346593", "title": "Enzymatic activities of the first two steps of liver HEME biosynthesis in experimental MHV-3 viral hepatitis.", "content": "Enzymatic activities of the first two steps of liver HEME biosynthesis in experimental MHV-3 viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346593"}
{"pmid": "4346594", "title": "Alteration of properties of cell contacts during progression of hepatomas.", "content": "Alteration of properties of cell contacts during progression of hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346594"}
{"pmid": "4346595", "title": "Localization of erythrocyte membrane antigens by immune electron microscopy.", "content": "Localization of erythrocyte membrane antigens by immune electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346595"}
{"pmid": "4346596", "title": "Effect of dibutyryl cyclic AMP on the restoration of contact inhibition in tumor cells and its relationship to cell density and the cell cycle.", "content": "Effect of dibutyryl cyclic AMP on the restoration of contact inhibition in tumor cells and its relationship to cell density and the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346596"}
{"pmid": "4346597", "title": "Health care policy issues in the 1970s.", "content": "Health care policy issues in the 1970s.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346597"}
{"pmid": "4346598", "title": "Studies on the terminal stages of complement lysis.", "content": "Studies on the terminal stages of complement lysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346598"}
{"pmid": "4346599", "title": "Antibody response to a protein antigen (ovalbumin) in dissociated spleen cell cultures from primed mice. Evidence for a suppressive effect of antigen.", "content": "Antibody response to a protein antigen (ovalbumin) in dissociated spleen cell cultures from primed mice. Evidence for a suppressive effect of antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346599"}
{"pmid": "4346602", "title": "Characteristics of \"big ACTH\" in human plasma and pituitary extracts.", "content": "Characteristics of \"big ACTH\" in human plasma and pituitary extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346602"}
{"pmid": "4346603", "title": "Cushing's disease with periodic hormonogenesis: one explanation for paradoxical response to dexamethasone.", "content": "Cushing's disease with periodic hormonogenesis: one explanation for paradoxical response to dexamethasone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346603"}
{"pmid": "4346604", "title": "A radioimmunoassay for plasma aldosterone without chromatography.", "content": "A radioimmunoassay for plasma aldosterone without chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346604"}
{"pmid": "4346605", "title": "Normal peroxidase activity in Pendred's syndrome.", "content": "Normal peroxidase activity in Pendred's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346605"}
{"pmid": "4346606", "title": "Similarity of the estrogen receptor in human and rat mammary carcinoma.", "content": "Similarity of the estrogen receptor in human and rat mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346606"}
{"pmid": "4346607", "title": "Immunochemical similarity between polysaccharide antigens of Escherichia coli 07: K1(L):NM and group B Neisseria meningitidis.", "content": "Immunochemical similarity between polysaccharide antigens of Escherichia coli 07: K1(L):NM and group B Neisseria meningitidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346607"}
{"pmid": "4346600", "title": "Neuronal and glial enzyme studies in cell culture.", "content": "Neuronal and glial enzyme studies in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346600"}
{"pmid": "4346610", "title": "Composition, structure and phase transition in yeast fatty acid auxotroph membranes: spin labels and freeze-fracture.", "content": "Composition, structure and phase transition in yeast fatty acid auxotroph membranes: spin labels and freeze-fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346610"}
{"pmid": "4346611", "title": "Structure of the lipid phase of Rauscher murine leukemia virus.", "content": "Structure of the lipid phase of Rauscher murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346611"}
{"pmid": "4346612", "title": "A spin label study of human erythrocyte carbonic anhydrases B and C.", "content": "A spin label study of human erythrocyte carbonic anhydrases B and C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346612"}
{"pmid": "4346614", "title": "Treatment of metastatic trophoblastic disease: good and poor prognosis.", "content": "Treatment of metastatic trophoblastic disease: good and poor prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346614"}
{"pmid": "4346615", "title": "Cell-mediated immunity in patients with ovarian carcinoma.", "content": "Cell-mediated immunity in patients with ovarian carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346615"}
{"pmid": "4346616", "title": "Ultrasonic diagnosis of Wilms' tumors.", "content": "Ultrasonic diagnosis of Wilms' tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346616"}
{"pmid": "4346617", "title": "Detection of feline syncytia-forming carrier state with a microimmunodiffusion test.", "content": "Detection of feline syncytia-forming carrier state with a microimmunodiffusion test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346617"}
{"pmid": "4346618", "title": "The ultrastructural pathology of the rat epididymis after administration of  -chlorhydrin (U-5897). I. Effects of a single high dose.", "content": "The ultrastructural pathology of the rat epididymis after administration of  -chlorhydrin (U-5897). I. Effects of a single high dose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346618"}
{"pmid": "4346626", "title": "Effects of irradiation on the survival of virus in West Coast oysters.", "content": "Effects of irradiation on the survival of virus in West Coast oysters. Gamma irradiation was evaluated as a means of inactivating poliovirus in shucked and whole shellfish. Results indicated that there was a significant survival of virus at all levels of radiation tested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346626"}
{"pmid": "4346628", "title": "Mutagenesis and enrichment of auxotrophs in Penicillium chrysogenum.", "content": "Mutagenesis and enrichment of auxotrophs in Penicillium chrysogenum. An efficient method for isolation of auxotrophs of Penicillium chyrysogenum involving mutagenesis with ethyl methanesulfonate followed by enrichment with sodium pentachlorophenate was developed. The auxotroph frequencies obtained were 30 to 40%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346628"}
{"pmid": "4346629", "title": "Properties of DNA treated with S-(1,2-dichlorovinyl)-L-cysteine and a lyase.", "content": "Properties of DNA treated with S-(1,2-dichlorovinyl)-L-cysteine and a lyase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346629"}
{"pmid": "4346630", "title": "Studies on the substrate specificity of hexosaminidase A and B from liver.", "content": "Studies on the substrate specificity of hexosaminidase A and B from liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346630"}
{"pmid": "4346627", "title": "Thermal injury and recovery of Bacillus subtilis.", "content": "Thermal injury and recovery of Bacillus subtilis. Exposure of Bacillus subtilis NCTC 8236 to sublethal temperatures produced a change in the sensitivity of the organism to salt and polymyxin. After 30 min at 47 C, 90% of the population was unable to grow on a modified sulfite polymyxin sulfadiazine agar containing an added 1% NaCl, 1% glucose, and 1% asparagine. The data presented demonstrate that thermal injury results in degradation of both 16S and 23S ribonucleic acid (RNA) and in damage to the cell membrane, suggested by leakage into the heating mestruum of material absorbing at 260 nm. When the cells were placed in a recovery medium (Trypticase soy broth), complete recovery, indicated by a returned tolerance to salt and polymyxin, occurred within 2 hr. The presence of a protein inhibitor (chloramphenicol) and cell wall inhibitors (vancomycin and penicillin) during recovery had no effect, whereas the presence of an RNA inhibitor (actinomycin D) effectively inhibited recovery. Further data demonstrated that the injured cells were able to resynthesize both species of ribosomal RNA during recovery by using the fragments which resulted from the injury process. Also, precursor 16S and precursor 23S particles accumulated during recovery. The maturation of the precursor particles during recovery was not affected by the presence of chloramphenicol in the recovery medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346627"}
{"pmid": "4346631", "title": "Studies of mitochondrial development prior to lactogenesis in the mouse mammary gland.", "content": "Studies of mitochondrial development prior to lactogenesis in the mouse mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346631"}
{"pmid": "4346632", "title": "Purification and properties of an endonuclease from Chlamydomonas.", "content": "Purification and properties of an endonuclease from Chlamydomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346632"}
{"pmid": "4346634", "title": "The oxidation-reduction potentials and rates of oxidation of the cytochromes of Nitrobacter agilis.", "content": "The oxidation-reduction potentials and rates of oxidation of the cytochromes of Nitrobacter agilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346634"}
{"pmid": "4346635", "title": "Electron paramagnetic resonance studies on nitrogenase. I. The properties of molybdoferredoxin and azoferredoxin.", "content": "Electron paramagnetic resonance studies on nitrogenase. I. The properties of molybdoferredoxin and azoferredoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346635"}
{"pmid": "4346633", "title": "Studies on cell adhesion. II. Adhesion of cells to surfaces of diverse chemical composition and inhibition of adhesion by sulfhydryl binding reagents.", "content": "Studies on cell adhesion. II. Adhesion of cells to surfaces of diverse chemical composition and inhibition of adhesion by sulfhydryl binding reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346633"}
{"pmid": "4346636", "title": "The covalent binding of D-fructose 1,6-diphosphate to muscle aldolase.", "content": "The covalent binding of D-fructose 1,6-diphosphate to muscle aldolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346636"}
{"pmid": "4346637", "title": "Purification and properties of a cyclic nucleotide phosphodiesterase from bovine heart.", "content": "Purification and properties of a cyclic nucleotide phosphodiesterase from bovine heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346637"}
{"pmid": "4346625", "title": "Postmortem changes in surface preparations of the cochlea.", "content": "Postmortem changes in surface preparations of the cochlea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346625"}
{"pmid": "4346639", "title": "Electron microscopic study of reticulohistiocytoma. An unusual case of congenital, self-healing reticulohistiocytosis.", "content": "Electron microscopic study of reticulohistiocytoma. An unusual case of congenital, self-healing reticulohistiocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346639"}
{"pmid": "4346638", "title": "Biogenesis of mitochondria: neuroendocrine effects on the development of respiratory functions in fat body mitochondria of the cockroach, Blaberus discoidalis.", "content": "Biogenesis of mitochondria: neuroendocrine effects on the development of respiratory functions in fat body mitochondria of the cockroach, Blaberus discoidalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346638"}
{"pmid": "4346641", "title": "Acceleration of protein synthesis by angiotensin--correlation with angiotensin's effect on catecholamine biosynthesis.", "content": "Acceleration of protein synthesis by angiotensin--correlation with angiotensin's effect on catecholamine biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346641"}
{"pmid": "4346640", "title": "Vitamin D metabolism. Recent advances.", "content": "Vitamin D metabolism. Recent advances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346640"}
{"pmid": "4346643", "title": "Hepatoma and hepatitis-associated antigen.", "content": "Hepatoma and hepatitis-associated antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346643"}
{"pmid": "4346646", "title": "The effect of an oral contraceptive on serum lipids.", "content": "The effect of an oral contraceptive on serum lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346646"}
{"pmid": "4346647", "title": "Steroid contraceptives and plasma carotenoids.", "content": "Steroid contraceptives and plasma carotenoids. Plasma vitamin-A and total carotenes were estimated by UV absorption of hexane extracts in Zambian women taking combined oral contraceptives or 150 mg Depo-Provera injected im at 3 month intervals, and in controls.  88 controls had a mean of 38 mcg/100 ml plasma vitamin-A and 151 mcg/100 ml total carotene.  48 women taking oral contraceptives for a mean of 17 months had 73 mcg/100 ml vitamin-A (p=.001) and 159 mcg/100 ml total carotene.  This increase in vitamin-A appeared in 1 month in a group of 12 who were tested before and after starting the pill.  24 women given injected progestin had 37 mcg/100 ml vitamin-A and 66 mcg/100 ml total carotene (p=.001).  This decrease in carotene appeared in 2-4 months in a group of 8 who were tested before and after injection.  A slight increase in vitamin-A at the end of a cycle of pills was the only difference observed during the cycle in these groups.  The authors noted that the increase in circulating vitamin-A, about 900 mcg, is far lower than the supplement of 3000 mcg daily widely prescribed for pregnant women, and not likely to be teratogenic in case of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346647"}
{"pmid": "4346648", "title": "Keratohyalin granule-like mitochondrial inclusion in the neonatal rat tongue and esophageal epithelia.", "content": "Keratohyalin granule-like mitochondrial inclusion in the neonatal rat tongue and esophageal epithelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346648"}
{"pmid": "4346649", "title": "The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21.", "content": "The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21. 13 independent mouse-human somatic cell hybrid clones derived from beta-propiolactone-inactivated Sendai stimulated cell fusion of human cells with mouse cells were tested for their sensitivities to human and mouse interferon. All of them were protected by mouse interferon and only six of the clones were protected by both human and mouse interferon. Only the six that were protected by human interferon were shown to express the human dimeric form of indophenol oxidase. Complete chromosomal analysis of the clones indicated human chromosome G-21 to be the only human chromosome in common for the six clones which had both phenotypes present. Nine subclones were derived from one of the clones expressing both phenotypes. Eight of the nine subclones were shown to retain both phenotypes, whereas one subclone lost both. Chromosomal analysis of the subclones indicated the loss of chromosome G-21 from the subclone which lost both phenotypes. It is apparent from these findings that the gene(s) for indophenol oxidase (IPO-B) and the gene(s) for the antiviral protein are syntenic and that they are linked to human chromosome G-21.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346649"}
{"pmid": "4346652", "title": "Replication of vesicular stomatitis virus: the effect of purified interfering component.", "content": "Replication of vesicular stomatitis virus: the effect of purified interfering component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346652"}
{"pmid": "4346650", "title": "Intrinsic interference between different enveloped RNA viruses.", "content": "Intrinsic interference between different enveloped RNA viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346650"}
{"pmid": "4346651", "title": "The effects of various protecting agents on the inactivation of foot-and-mouth disease virus in aerosols and during freeze-drying.", "content": "The effects of various protecting agents on the inactivation of foot-and-mouth disease virus in aerosols and during freeze-drying.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346651"}
{"pmid": "4346653", "title": "Electron microscopic studies on the development of infectious bovine rhinotracheitis virus in bovine kidney cells.", "content": "Electron microscopic studies on the development of infectious bovine rhinotracheitis virus in bovine kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346653"}
{"pmid": "4346654", "title": "Purification of mengovirus and identification of an A-rich segment in its ribonucleic acid.", "content": "Purification of mengovirus and identification of an A-rich segment in its ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346654"}
{"pmid": "4346655", "title": "Reovirus type 3 encephalitis--a virologic and ultrastructural study.", "content": "Reovirus type 3 encephalitis--a virologic and ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346655"}
{"pmid": "4346656", "title": "Subacute focal adenovirus encephalitis.", "content": "Subacute focal adenovirus encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346656"}
{"pmid": "4346657", "title": "Murine influenza virus encephalomyelitis. I. Neuropathological and immunofluorescence findings.", "content": "Murine influenza virus encephalomyelitis. I. Neuropathological and immunofluorescence findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346657"}
{"pmid": "4346658", "title": "Murine influenza virus encephalomyelitis. II. Electron microscopic observations.", "content": "Murine influenza virus encephalomyelitis. II. Electron microscopic observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346658"}
{"pmid": "4346659", "title": "Granular cell tumors of the central nervous system.", "content": "Granular cell tumors of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346659"}
{"pmid": "4346661", "title": "Control of renin secretion.", "content": "Control of renin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346661"}
{"pmid": "4346662", "title": "The current state of immunity to polioviruses in New South Wales.", "content": "The current state of immunity to polioviruses in New South Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346662"}
{"pmid": "4346664", "title": "Salivary gland disorders. II. Salivary tumors.", "content": "Salivary gland disorders. II. Salivary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346664"}
{"pmid": "4346665", "title": "Peripheral neuropathy with ethambutol.", "content": "Peripheral neuropathy with ethambutol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346665"}
{"pmid": "4346666", "title": "Maternal bronchial carcinoma and its possible relation to neonatal hypoglycaemia.", "content": "Maternal bronchial carcinoma and its possible relation to neonatal hypoglycaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346666"}
{"pmid": "4346667", "title": "Posterior fossa cisternography.", "content": "Posterior fossa cisternography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346667"}
{"pmid": "4346668", "title": "The hypothalamo-hypophysial system in Acipenseridae. 3. The neurohypophysis of Acipenser güldenstädti Brandt and Acipenser stellatus Pallas.", "content": "The hypothalamo-hypophysial system in Acipenseridae. 3. The neurohypophysis of Acipenser güldenstädti Brandt and Acipenser stellatus Pallas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346668"}
{"pmid": "4346670", "title": "The fine structure of the pancreatic nerves of the domestic fowl.", "content": "The fine structure of the pancreatic nerves of the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346670"}
{"pmid": "4346669", "title": "Ultrastructural observations on the pars descendens of the proximal tubule in the kidney of the male rat.", "content": "Ultrastructural observations on the pars descendens of the proximal tubule in the kidney of the male rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346669"}
{"pmid": "4346671", "title": "Unique sensory endings in rat muscle spindles.", "content": "Unique sensory endings in rat muscle spindles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346671"}
{"pmid": "4346672", "title": "The fine structure of the branchial heart appendage of the cephalopod Octopus dofleini martini.", "content": "The fine structure of the branchial heart appendage of the cephalopod Octopus dofleini martini.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346672"}
{"pmid": "4346674", "title": "The differentiation of foot-and-mouth disease virus subtypes by means of the passive immuno-hemolysis test.", "content": "The differentiation of foot-and-mouth disease virus subtypes by means of the passive immuno-hemolysis test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346674"}
{"pmid": "4346677", "title": "Hexoestrol analogues as probes of oestrogen receptors. I. Importance of hydrogen-bonding groups for receptor binding.", "content": "Hexoestrol analogues as probes of oestrogen receptors. I. Importance of hydrogen-bonding groups for receptor binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346677"}
{"pmid": "4346676", "title": "Studies on mechanical actions of mepivacaine (Carbocaine) and its optically active isomers on isolated smooth muscle: role of Ca ++  and cyclic AMP.", "content": "Studies on mechanical actions of mepivacaine (Carbocaine) and its optically active isomers on isolated smooth muscle: role of Ca ++  and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346676"}
{"pmid": "4346678", "title": "Hexoestrol analogues as probes of oestrogen receptors. II. Importance of hydrogen-bonding groups for binding to uterine tissue and for uterotrophic activity.", "content": "Hexoestrol analogues as probes of oestrogen receptors. II. Importance of hydrogen-bonding groups for binding to uterine tissue and for uterotrophic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346678"}
{"pmid": "4346679", "title": "Ampicillin rash in children. Relationship to penicillin allergy and infectious mononucleosis.", "content": "Ampicillin rash in children. Relationship to penicillin allergy and infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346679"}
{"pmid": "4346680", "title": "Inheritance of combined hyperlipoproteinemia: evidence for a new lipoprotein phenotype.", "content": "Inheritance of combined hyperlipoproteinemia: evidence for a new lipoprotein phenotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346680"}
{"pmid": "4346681", "title": "Plasma testosterone stimulation-suppression dynamics in hirsute women. correlation with long-term therapy.", "content": "Plasma testosterone stimulation-suppression dynamics in hirsute women. correlation with long-term therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346681"}
{"pmid": "4346682", "title": "Virilizing luteoma of pregnancy. Report of a case with measurements of testosterone and testosterone binding in plasma.", "content": "Virilizing luteoma of pregnancy. Report of a case with measurements of testosterone and testosterone binding in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346682"}
{"pmid": "4346683", "title": "Studies of platelet adhesiveness, glucose tolerance and serum liporotein patterns in patients with coronary artery disease.", "content": "Studies of platelet adhesiveness, glucose tolerance and serum liporotein patterns in patients with coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346683"}
{"pmid": "4346684", "title": "Arteriographic findings of focal nodular hyperplasia of the liver and review of the literature.", "content": "Arteriographic findings of focal nodular hyperplasia of the liver and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346684"}
{"pmid": "4346685", "title": "Endoscopic pancreato-cholangiography. A preliminary report on technique and diagnostic significance.", "content": "Endoscopic pancreato-cholangiography. A preliminary report on technique and diagnostic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346685"}
{"pmid": "4346688", "title": "Bacterial flora in the duodenum of patients after biliary fenestration.", "content": "Bacterial flora in the duodenum of patients after biliary fenestration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346688"}
{"pmid": "4346689", "title": "Chlorpromazine in malignant insulinoma.", "content": "Chlorpromazine in malignant insulinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346689"}
{"pmid": "4346690", "title": "Tumor hypercalcemia.", "content": "Tumor hypercalcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346690"}
{"pmid": "4346692", "title": "Effects of caudate stimulation on unitary responses of the lateral geniculate body to light.", "content": "Effects of caudate stimulation on unitary responses of the lateral geniculate body to light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346692"}
{"pmid": "4346691", "title": "Association of ectopically produced hyperparathyroidism with hepatoma.", "content": "Association of ectopically produced hyperparathyroidism with hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346691"}
{"pmid": "4346693", "title": "Effect of tetanus toxin on the inhibitory neuromuscular junction of crayfish muscle.", "content": "Effect of tetanus toxin on the inhibitory neuromuscular junction of crayfish muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346693"}
{"pmid": "4346694", "title": "Myelin hypoplasia including peripheral neuropathy caused by three mutations of the mouse.", "content": "Myelin hypoplasia including peripheral neuropathy caused by three mutations of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346694"}
{"pmid": "4346695", "title": "Effects of guanidine derivatives on mitochondrial function. IV. Changes in citric acid cycle intermediates and NADH.", "content": "Effects of guanidine derivatives on mitochondrial function. IV. Changes in citric acid cycle intermediates and NADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346695"}
{"pmid": "4346697", "title": "The response of normal and polyoma virus-transformed BHK-21 cells to exogenous purines.", "content": "The response of normal and polyoma virus-transformed BHK-21 cells to exogenous purines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346697"}
{"pmid": "4346696", "title": "Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. IV. Nucleoside transport in cells depleted of nucleotides by treatment with KCN.", "content": "Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. IV. Nucleoside transport in cells depleted of nucleotides by treatment with KCN.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346696"}
{"pmid": "4346698", "title": "Loss of density-dependent regulation of multiplication of BALB-3T3 cells chemically transformed in vitro.", "content": "Loss of density-dependent regulation of multiplication of BALB-3T3 cells chemically transformed in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346698"}
{"pmid": "4346700", "title": "Influence of acetylcholine on contractile force and cyclic nucleotide levels in the isolated perfused rat heart.", "content": "Influence of acetylcholine on contractile force and cyclic nucleotide levels in the isolated perfused rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346700"}
{"pmid": "4346701", "title": "Decreased contractility and norepinephrine content of guinea-pig seminal vesicles after chronic treatment with testosterone.", "content": "Decreased contractility and norepinephrine content of guinea-pig seminal vesicles after chronic treatment with testosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346701"}
{"pmid": "4346703", "title": "Delayed release of transmitter at the frog neuromuscular junction.", "content": "Delayed release of transmitter at the frog neuromuscular junction. 1. After the end-plate potential (e.p.p.) there is an increase in the frequency of the miniature e.p.p.s. This delayed release of transmitter was studied at the frog neuromuscular junction, using conventional intracellular and extracellular recording techniques. E.p.p. amplitude was kept subthreshold by subnormal concentrations of activating divalent ions.2. The ratio delayed release: initial release had values between 2 and 140%, depending on the experimental conditions; it decreased with an increase in Ca concentration and quantal content.3. Delayed release is larger at low temperature than at room temperature.4. Delayed release is statistically independent of the amplitude of the preceding e.p.p.5. The time course of the decay of the delayed release is monotonic when strontium is the activating divalent ion; it shows a ;dip' in more than 50% of the cases when Ca activated release.6. The results were discussed in terms of the residual Ca ion hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346703"}
{"pmid": "4346702", "title": "The effects of tetanus toxin on neuromuscular transmission and on the morphology of motor end-plates in slow and fast skeletal muscle of the mouse.", "content": "The effects of tetanus toxin on neuromuscular transmission and on the morphology of motor end-plates in slow and fast skeletal muscle of the mouse. 1. A sublethal dose of tetanus toxin was injected into the muscles of one hind leg of the mouse and caused local tetanus which persisted for 4 weeks.2. Neuromuscular transmission was studied in vitro in nerve-muscle preparations of soleus, a slow muscle, and extensor digitorum longus (EDL), a fast muscle, from 1 day to 6 months after the injection of toxin.3. Soleus failed to respond to nerve stimulation, became supersensitive to acetylcholine and showed spontaneous fibrillations for several weeks before returning to normal. EDL did not show these changes. A higher dose of tetanus toxin, lethal within 24 hr, caused paralysis of EDL as well as soleus.4. In muscle fibres in which neuromuscular transmission was blocked spontaneous miniature end-plate potentials (m.e.p.p.s) were recorded. The frequency of m.e.p.p.s was increased by repetitive nerve stimulation but not by raising the external potassium concentration.5. The amplitude of spontaneous m.e.p.p.s showed a skew distribution because of a disproportionate number of potentials of less than 0.2 mV.6. Raising the external calcium concentration did not restore neuromuscular transmission.7. Histological examination of soleus showed atrophy of muscle fibres with normal preterminal axons. There was sprouting from motor nerve terminals and subsequently new motor end-plates were formed. These changes were not found in EDL.8. The results indicate that, in the mouse, tetanus toxin causes a presynaptic block of neuromuscular transmission and ;functional denervation' of muscle. Slow muscle is more sensitive to the effects of the toxin than fast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346702"}
{"pmid": "4346704", "title": "Synaptic frequency response: the influence of sinusoidal changes in stimulation frequency on the amplitude of the end-plate potential.", "content": "Synaptic frequency response: the influence of sinusoidal changes in stimulation frequency on the amplitude of the end-plate potential. 1. The synaptic response to frequency modulated trains of stimuli was investigated at the neuromuscular junction of the frog. The frequency of stimulation was usually varied sinusoidally about a carrier frequency of ca. 25 impulses per sec (Hz).2. The post-synaptic response to sinusoidally modulated trains of nerve stimuli was found to grow almost linearly when the variations in input frequency were increased up to 60% of the carrier frequency.3. The synaptic frequency response (gain and phase) was reminiscent of that of a low-pass filter, best transmitting slow variations in input frequency.4. The synaptic filter characteristics could not be explained by the post-synaptic cable properties, but were attributed to presynaptic facilitation processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346704"}
{"pmid": "4346707", "title": "Treatment of anaerobic infections with lincomycin and clindamycin.", "content": "Treatment of anaerobic infections with lincomycin and clindamycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346707"}
{"pmid": "4346708", "title": "Genetic manipulation of reovirus--a model for modification of disease.", "content": "Genetic manipulation of reovirus--a model for modification of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346708"}
{"pmid": "4346709", "title": "Release of amino-acids and neurosecretory substances after stimulation of nerve-endings (synaptosomes) isolated from the hypothalamus.", "content": "Release of amino-acids and neurosecretory substances after stimulation of nerve-endings (synaptosomes) isolated from the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346709"}
{"pmid": "4346710", "title": "Tumours of the nervous system in mice treated neonatally with N-ethyl-N-nitrosourea.", "content": "Tumours of the nervous system in mice treated neonatally with N-ethyl-N-nitrosourea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346710"}
{"pmid": "4346712", "title": "Biosynthesis of aortic vascular graft tissue in the pig.", "content": "Biosynthesis of aortic vascular graft tissue in the pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346712"}
{"pmid": "4346730", "title": "Some histochemical, biochemical and morphological observations relating to lipofuscin and mitochondria.", "content": "Some histochemical, biochemical and morphological observations relating to lipofuscin and mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346730"}
{"pmid": "4346731", "title": "Theophylline inhibits the transcription of the lac operon in Escherichia coli.", "content": "Theophylline inhibits the transcription of the lac operon in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346731"}
{"pmid": "4346732", "title": "Immunofluorescence studies on tissue cultures doubly infected with adeno and herpesviruses.", "content": "Immunofluorescence studies on tissue cultures doubly infected with adeno and herpesviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346732"}
{"pmid": "4346735", "title": "Calcium-membrane interactions in the myocardium: effects of ouabain, epinephrine and 3',5'-cyclic adenosine monophosphate.", "content": "Calcium-membrane interactions in the myocardium: effects of ouabain, epinephrine and 3',5'-cyclic adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346735"}
{"pmid": "4346736", "title": "Hematologic complications of open heart surgery.", "content": "Hematologic complications of open heart surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346736"}
{"pmid": "4346737", "title": "Physician in Gilead.", "content": "Physician in Gilead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346737"}
{"pmid": "4346738", "title": "Syngeneic skin graft rejection associated with oncogenic viruses.", "content": "Syngeneic skin graft rejection associated with oncogenic viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346738"}
{"pmid": "4346739", "title": "Cerebral angiography and subtraction in neuro-otologic diagnosis.", "content": "Cerebral angiography and subtraction in neuro-otologic diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346739"}
{"pmid": "4346740", "title": "Pneumographic and isotopic procedures in neuro-otologic diagnosis.", "content": "Pneumographic and isotopic procedures in neuro-otologic diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346740"}
{"pmid": "4346741", "title": "Bell's palsy.", "content": "Bell's palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346741"}
{"pmid": "4346742", "title": "A review of viral infections of horses.", "content": "A review of viral infections of horses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346742"}
{"pmid": "4346743", "title": "General ligands in affinity chromatography. Cofactor-substrate elution of enzymes bound to the immobilized nucleotides adenosine 5'-monophosphate and nicotinamide-adenine dinucleotide.", "content": "General ligands in affinity chromatography. Cofactor-substrate elution of enzymes bound to the immobilized nucleotides adenosine 5'-monophosphate and nicotinamide-adenine dinucleotide. 1. Two different gels have been prepared suitable for the separation of a number of enzymes, in particular NAD(+)-dependent dehydrogenases, by affinity chromatography. For both the matrix used was Sepharose 4B. For preparation (a), NAD(+)-Sepharose, 6-aminohexanoic acid has been coupled to the gel by the cyanogen bromide method and then NAD(+) was attached by using dicyclohexylcarbodi-imide; for preparation (b), AMP-Sepharose, N(6)-(6-aminohexyl)-AMP has been coupled directly to cyanogen bromide-activated gel. 2. Affinity columns of both gels retain only the two enzymes when a mixture of bovine serum albumin, lactate dehydrogenase and glyceraldehyde 3-phosphate dehydrogenase is applied. Subsequent elution with the cofactor NAD(+) yields glyceraldehyde 3-phosphate dehydrogenase whereas lactate dehydrogenase is eluted by applying the same molarity of the reduced cofactor. 3. The binding of both glyceraldehyde 3-phosphate dehydrogenase and lactate dehydrogenase to the gel tested, AMP-Sepharose, is strong enough to resist elution by gradients of KCl of up to at least 0.5m. A 0.0-0.15m gradient of the competitive inhibitor salicylate, however, elutes both enzymes efficiently and separately. 4. The elution efficiency of lactate dehydrogenase from AMP-Sepharose has been examined by using a series of eluents under comparable conditions of concentration etc. The approximate relative efficiencies are: 0 (lactate); 0 (lactate+semicarbazide); 0 (0.5mm-NAD(+)); 80 (lactate+NAD(+)); 95 (lactate+semicarbazide+NAD(+)); 100 (0.5mm-NADH). 5. All contaminating lactate dehydrogenase activity can be removed from commercially available crude pyruvate kinase in a single-step procedure by using AMP-Sepharose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346743"}
{"pmid": "4346744", "title": "Intracellular localization of aldehyde dehydrogenase in rat liver.", "content": "Intracellular localization of aldehyde dehydrogenase in rat liver. 1. Distribution of aldehyde dehydrogenase activity in rat liver was studied by measuring the rate of disappearance of acetaldehyde in the presence of each of the subcellular fractions. These were obtained by rough separation of particulate fractions from the soluble portion of the cell, by differential centrifugation, and by isopycnic gradient centrifugation. 2. The maximal rate of acetaldehyde oxidation was 3.7 mumol/min per g, with an apparent K(m) value below 10(-5)m. The highest rate of activity was observed in phosphate buffers of high P(i) concentration (above 60mm). 3. The activity measured was completely dependent on NAD(+). 4. The microsomal fraction and the nuclei were inactive in the assay. Of the total activity 80% was found in the mitochondrial fraction and the remaining 20% in the cytoplasm. 5. The distribution pattern is important from the point of view of acetaldehyde oxidation during ethanol metabolism. The apparent discrepancy of the results obtained by different workers and the localization of acetaldehyde oxidation in vivo is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346744"}
{"pmid": "4346746", "title": "Lipid composition of membranes of amine-storage organelles.", "content": "Lipid composition of membranes of amine-storage organelles. 1. The lipid composition of the membranes from isolated 5-hydroxytryptamine-storage organelles of blood platelets of rabbits and of those from chromaffin granules of bovine adrenal medulla was compared. 2. In contrast with the membranes of the chromaffin granules, those of the 5-hydroxytryptamine organelles did not contain lysophosphatidylcholine (lysolecithin). 3. Both the cholesterol/phospholipid ratio and the relative proportions of phosphatidylethanolamine (kephalin), phosphatidylinositol and phosphatidylserine were about the same in both membranes, whereas phosphatidylcholine (lecithin) and sphingomyelin showed somewhat higher values in the membranes of the 5-hydroxytryptamine organelles. 4. In conclusion, the release of 5-hydroxytryptamine from blood platelets is probably not correlated with the presence of lysophosphatidylcholine in the membranes of the storage organelles and may thus differ from the mechanism of catecholamine release in adrenal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346746"}
{"pmid": "4346745", "title": "The expression of catechol oxidase activity during the hydroxylation of p-coumaric acid by spinach-beet phenolase.", "content": "The expression of catechol oxidase activity during the hydroxylation of p-coumaric acid by spinach-beet phenolase. 1. The conditions under which oxygen consumption in excess of that required for the hydroxylation of p-coumaric acid to caffeic acid, catalysed by spinach-beet phenolase, can be suppressed, have been examined. 2. With dimethyltetrahydropteridine as electron donor, oxygen uptake was exactly equivalent to the caffeic acid produced, provided that p-coumaric acid was in excess, but with excess of reductant, oxygen uptake caused by the further oxidation of caffeic acid was also observed. 3. With equal concentrations of ascorbate and p-coumaric acid, equivalent oxygen uptake and caffeic acid production was found only in the first stages of the reaction, whereas with NADH substituted for ascorbate, oxygen uptake was in excess throughout. 4. When ascorbate was used, the period of the reaction over which this equivalence was found was decreased at high reaction rates and not observed at all with aged enzyme preparations; equivalence was restored by adding bovine serum albumin to these aged preparations. 5. Equivalence between oxygen consumption and caffeic acid production was observed with NADH, if small quantities of dimethyltetrahydropteridine were also added. 6. It is concluded that hydroxylation proceeds without the concomitant production of caffeic acid only if the enzyme is stabilized for hydroxylation by p-coumaric acid and the reductant, and is protected from attack by o-quinones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346745"}
{"pmid": "4346748", "title": "Carbohydrate content and glycogenolytic acitivity in human placenta and fetal heart and lung.", "content": "Carbohydrate content and glycogenolytic acitivity in human placenta and fetal heart and lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346748"}
{"pmid": "4346747", "title": "N 6 -(  2 -isopentenyl) adenosine: biosynthesis in vitro in transfer RNA by an enzyme purified from Escherichia coli.", "content": "N 6 -(  2 -isopentenyl) adenosine: biosynthesis in vitro in transfer RNA by an enzyme purified from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346747"}
{"pmid": "4346749", "title": "First cleavage division of the mouse zygot. An ultrastructural study.", "content": "First cleavage division of the mouse zygot. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346749"}
{"pmid": "4346750", "title": "Evolution of the apical body in golden hamster spermatids with some reference to primates.", "content": "Evolution of the apical body in golden hamster spermatids with some reference to primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346750"}
{"pmid": "4346753", "title": "Isolation of arginine acceptor-proteins from normal rat liver and Novikoff hepatoma supernatant.", "content": "Isolation of arginine acceptor-proteins from normal rat liver and Novikoff hepatoma supernatant. In the present report a procedure for the isolation of more specific arginine receptors from the soluble fraction of rat liver and Novikoff hepatoma is described. In normal rat liver the specific activity of these receptors from the soluble fraction of rat liver and Novikoff hepatoma is described. In normal rat liver the specific activity of these receptors is fifteen times greater than that of the other proteins whereas in the Novikoff it is only three to four times higher. Attempts to sub-fractionate this class of acceptors would seem to indicate a relative homogeneity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346753"}
{"pmid": "4346752", "title": "Immunological control of polyoma virus oncogenesis in mice.", "content": "Immunological control of polyoma virus oncogenesis in mice. Adult CBA mice thymectomized, treated with antilymphocytic globulin (ALG) and inoculated with human leprosy organisms were accidentally infected with polyoma virus and all developed tumours. After cessation of ALG administration, some animals were given spleen cells from syngeneic donors immunized with polyoma virus; none developed tumours. Similar results were obtained in mice deliberately infected with polyoma virus but not with leprosy organisms. Passive transfer of antibody before but not after virus inoculation prevented tumour formation in immunosuppressed recipients. Virus infection in thymectomized, lethally irradiated and bone marrow reconstituted mice resulted in only a very low incidence of tumours. These results emphasize the role of immunological surveillance in preventing polyoma tumour formation under natural conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346752"}
{"pmid": "4346754", "title": "Effect of alloxan diabetes, insulin & diabetogenic hormones on intestinal transport of tyrosine in rats.", "content": "Effect of alloxan diabetes, insulin & diabetogenic hormones on intestinal transport of tyrosine in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346754"}
{"pmid": "4346755", "title": "Identification and typing of clostridia in raw milk in Egypt.", "content": "Identification and typing of clostridia in raw milk in Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346755"}
{"pmid": "4346756", "title": "New culture conditions for Clostirdium histolyticum leading to production of collagenase of high specific activity.", "content": "New culture conditions for Clostirdium histolyticum leading to production of collagenase of high specific activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346756"}
{"pmid": "4346757", "title": "Atypical sarcoma of the iliotibial band.", "content": "Atypical sarcoma of the iliotibial band.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346757"}
{"pmid": "4346758", "title": "The value of plasma testosterone estimation in the diagnosis of virilizing ovarian neoplasia.", "content": "The value of plasma testosterone estimation in the diagnosis of virilizing ovarian neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346758"}
{"pmid": "4346759", "title": "A stucy on the effect of aldosterone on the extramitochondrial adenine nucleotide system in rat kidney.", "content": "A stucy on the effect of aldosterone on the extramitochondrial adenine nucleotide system in rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346759"}
{"pmid": "4346760", "title": "Glucocorticoid and mineralocorticoid receptors for aldosterone.", "content": "Glucocorticoid and mineralocorticoid receptors for aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346760"}
{"pmid": "4346762", "title": "Evaluation of the Sellers-Schmidt-ball rapid antibiotic susceptibility test.", "content": "Evaluation of the Sellers-Schmidt-ball rapid antibiotic susceptibility test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346762"}
{"pmid": "4346761", "title": "Conversion of cystitis glandularis to adenocarcinoma.", "content": "Conversion of cystitis glandularis to adenocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346761"}
{"pmid": "4346763", "title": "The cytology of urine of pediatric cancer patients.", "content": "The cytology of urine of pediatric cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346763"}
{"pmid": "4346764", "title": "[Abnormalities of sodium and water metabolism with special reference to hypertensive diseases].", "content": "[Abnormalities of sodium and water metabolism with special reference to hypertensive diseases].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346764"}
{"pmid": "4346770", "title": "Characterisation of derepressed mutants of an F-like R factor.", "content": "Characterisation of derepressed mutants of an F-like R factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346770"}
{"pmid": "4346769", "title": "A colicin-tolerant mutant of Escherichia coli with reduced levels of cyclic AMP and a strong bias towards lambda lysogeny.", "content": "A colicin-tolerant mutant of Escherichia coli with reduced levels of cyclic AMP and a strong bias towards lambda lysogeny.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346769"}
{"pmid": "4346772", "title": "Thirst and the limbic system.", "content": "Thirst and the limbic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346772"}
{"pmid": "4346774", "title": "Immunological aspects of Hodgkin's disease.", "content": "Immunological aspects of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346774"}
{"pmid": "4346773", "title": "Melkersson's syndrome.", "content": "Melkersson's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346773"}
{"pmid": "4346775", "title": "The cancer cell.", "content": "The cancer cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346775"}
{"pmid": "4346785", "title": "Ultrastructure of the nerves and sense receptors of Polystomoides renschi Rohde and P. malayi Rohde (Monogenea: Polystomatidae).", "content": "Ultrastructure of the nerves and sense receptors of Polystomoides renschi Rohde and P. malayi Rohde (Monogenea: Polystomatidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346785"}
{"pmid": "4346787", "title": "The quantitative dermination of quartz in coal dust by infrared spectroscopy.", "content": "The quantitative dermination of quartz in coal dust by infrared spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346787"}
{"pmid": "4346788", "title": "Toxicity of a substituted hydrazine for turkeys.", "content": "Toxicity of a substituted hydrazine for turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346788"}
{"pmid": "4346789", "title": "Morphological changes in livers of rats fed polychlorinated biphenyls: light microscopy and ultrastructure.", "content": "Morphological changes in livers of rats fed polychlorinated biphenyls: light microscopy and ultrastructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346789"}
{"pmid": "4346796", "title": "Studies on the wholesomeness of ready-to-eat meat products. I. Bacteriological evaluation of comminuted heated products.", "content": "Studies on the wholesomeness of ready-to-eat meat products. I. Bacteriological evaluation of comminuted heated products. Bacteriological studies were conducted on comminuted heated types of ready-to-eat meat products. Seventy-five per cent of the samples showed total counts in the range of 100-10,000 organisms per gm. Of potential food poisoning organisms, coagulase positive staphylococci were present in 4% and Clostridium perfringens in 1.7% of all samples in low numbers. Of indicator organisms for fecal and sewage contamination, Escherichia coli were found in 3.2% and Streptococcus fecalis in 5.4% of the samples. The heat treatment applied during processing is not sufficient to destroy these organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346796"}
{"pmid": "4346797", "title": "Stimulation of adrenal ornithine decarboxylase by adrenocorticotropin and growth hormone.", "content": "Stimulation of adrenal ornithine decarboxylase by adrenocorticotropin and growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346797"}
{"pmid": "4346798", "title": "Effect of polyphloretin phosphate on the induction of thyroid hormone secretion by various thyroid stimulators.", "content": "Effect of polyphloretin phosphate on the induction of thyroid hormone secretion by various thyroid stimulators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346798"}
{"pmid": "4346799", "title": "A model for the evaluation of estrogens: withdrawal bleeding in ovariectomized rhesus monkeys.", "content": "A model for the evaluation of estrogens: withdrawal bleeding in ovariectomized rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346799"}
{"pmid": "4346800", "title": "Studies of the levels and synthesis of cytochrome c during adult development of the blowfly Lucilia cuprina.", "content": "Studies of the levels and synthesis of cytochrome c during adult development of the blowfly Lucilia cuprina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346800"}
{"pmid": "4346801", "title": "Phosphofructokinase activity in skeletal muscle extracts following administration of epinephrine.", "content": "Phosphofructokinase activity in skeletal muscle extracts following administration of epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346801"}
{"pmid": "4346802", "title": "Fish liver fructose 1,6-diphosphatase. I. Purification of the enzyme from Genypterus chilensis and studies on adenosine 5'-monophosphate inhibition.", "content": "Fish liver fructose 1,6-diphosphatase. I. Purification of the enzyme from Genypterus chilensis and studies on adenosine 5'-monophosphate inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346802"}
{"pmid": "4346803", "title": "Properties of modified cytochromes. I. Equilibrium and kinetics of the pH-dependent transition in carboxymethylated horse heart cytochrome c.", "content": "Properties of modified cytochromes. I. Equilibrium and kinetics of the pH-dependent transition in carboxymethylated horse heart cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346803"}
{"pmid": "4346804", "title": "Preparation of the heme protein P-450 from the adrenal cortex and some of its properties.", "content": "Preparation of the heme protein P-450 from the adrenal cortex and some of its properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346804"}
{"pmid": "4346806", "title": "Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human erythrocyte membranes.", "content": "Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346806"}
{"pmid": "4346805", "title": "Glycoproteins and blood group activity. I. Oligosaccharides of serologically inactive hog submaxillary glycoproteins.", "content": "Glycoproteins and blood group activity. I. Oligosaccharides of serologically inactive hog submaxillary glycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346805"}
{"pmid": "4346807", "title": "Calcium-mediated interactions between the antidiuretic hormone and renal plasma membranes.", "content": "Calcium-mediated interactions between the antidiuretic hormone and renal plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346807"}
{"pmid": "4346808", "title": "Inactivation of hormone-sensitive lipase in extracts of adipose tissue.", "content": "Inactivation of hormone-sensitive lipase in extracts of adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346808"}
{"pmid": "4346809", "title": "Catalysis of  -iminoglutarate formation from  -ketoglutarate and ammonia by bovine glutamate dehydrogenase.", "content": "Catalysis of  -iminoglutarate formation from  -ketoglutarate and ammonia by bovine glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346809"}
{"pmid": "4346812", "title": "ACTH-induced alterations in catecholamine metabolism in man.", "content": "ACTH-induced alterations in catecholamine metabolism in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346812"}
{"pmid": "4346810", "title": "Transport of succinate in Escherichia coli. I. Biochemical and genetic studies of transport in whole cells.", "content": "Transport of succinate in Escherichia coli. I. Biochemical and genetic studies of transport in whole cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346810"}
{"pmid": "4346813", "title": "A kindred with familial glucocorticoid suppressible aldosteronism.", "content": "A kindred with familial glucocorticoid suppressible aldosteronism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346813"}
{"pmid": "4346811", "title": "Protein synthesis in single cell suspensions from rat liver. I. General properties of the system and permeability of the cells for leucine and methionine.", "content": "Protein synthesis in single cell suspensions from rat liver. I. General properties of the system and permeability of the cells for leucine and methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346811"}
{"pmid": "4346814", "title": "Dissociation of MSH and ACTH release in man.", "content": "Dissociation of MSH and ACTH release in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346814"}
{"pmid": "4346815", "title": "Steroid determination from complex mixtures by high pressure chromatographic techniques.", "content": "Steroid determination from complex mixtures by high pressure chromatographic techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346815"}
{"pmid": "4346816", "title": "Clinical use of radioimmunological plasma insulin assessment.", "content": "Clinical use of radioimmunological plasma insulin assessment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346816"}
{"pmid": "4346819", "title": "Apicoectomy as an adjunct to diagnosis.", "content": "Apicoectomy as an adjunct to diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346819"}
{"pmid": "4346825", "title": "Adenosine 3',5'-monophosphate in pancreatic islets: glucose-induced insulin release.", "content": "Adenosine 3',5'-monophosphate in pancreatic islets: glucose-induced insulin release. Glucose-induced release of insulin from perifused rat islets is associated with elevated islet adenosine 3',5'-monophosphate. If values for adenosine 3',5'-monophosphate are compared to insulin release during theophylline or glucose stimulation and theophylline plus glucose stimulation, it suggests a minor role for adenosine 3',5'-monophosphate in directly stimulating insulin release but a prominent role in modulating glucose-induced release of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346825"}
{"pmid": "4346824", "title": "Cholera: new aids in treatment and prevention.", "content": "Cholera: new aids in treatment and prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346824"}
{"pmid": "4346826", "title": "Noradrenergic stimulation of cyclic adenosine monophosphate in rat Purkinje neurons: an immunocytochemical study.", "content": "Noradrenergic stimulation of cyclic adenosine monophosphate in rat Purkinje neurons: an immunocytochemical study. A specific immunofluorescent histochemical method for cyclic adenosine monophosphate was used to study rat cerebellum. After topical treatment with norepinephrine or stimulation of norepinephrine-containing afferents from locus coeruleus, there was a striking increase in the number of Purkinje cells with strong cyclic adenosine monophosphate reactivity. Other putative inhibitory transmitters had no significant effect on staining of Purkinje cells. The results provide the first histochemical support for the hypothesis that cyclic adenosine monophosphate can be generated postsynaptically in central neurons in response to noradrenergic stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346826"}
{"pmid": "4346844", "title": "Nonuniformity of sympathetic nerve activity to the skin and kidney.", "content": "Nonuniformity of sympathetic nerve activity to the skin and kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346844"}
{"pmid": "4346845", "title": "Intracellular Cl concentrations and influxes across the brush border of rabbit ileum.", "content": "Intracellular Cl concentrations and influxes across the brush border of rabbit ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346845"}
{"pmid": "4346846", "title": "Interrelationship of cyclic AMP, lipolysis, and respiration in brown fat cells.", "content": "Interrelationship of cyclic AMP, lipolysis, and respiration in brown fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346846"}
{"pmid": "4346847", "title": "Ouabain-sensitive component of brown fat thermogenesis.", "content": "Ouabain-sensitive component of brown fat thermogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346847"}
{"pmid": "4346848", "title": "Intrarenal secretion of renin in the dog: effect of furosemide.", "content": "Intrarenal secretion of renin in the dog: effect of furosemide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346848"}
{"pmid": "4346849", "title": "Malignant giant cell tumor of the tendon sheath. Ultrastructural study and review of the literature.", "content": "Malignant giant cell tumor of the tendon sheath. Ultrastructural study and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346849"}
{"pmid": "4346850", "title": "Myoepithelioma of the palate. Histochemical and ultrastructural observations.", "content": "Myoepithelioma of the palate. Histochemical and ultrastructural observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346850"}
{"pmid": "4346851", "title": "Gallbladder bacteriology, histology, and gallstones. Study of unselected cholecystectomy specimens in Honolulu.", "content": "Gallbladder bacteriology, histology, and gallstones. Study of unselected cholecystectomy specimens in Honolulu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346851"}
{"pmid": "4346852", "title": "Biochemical variability in the skin.", "content": "Biochemical variability in the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346852"}
{"pmid": "4346853", "title": "Acceleration of catecholamine biosynthesis in sympathetically innervated tissues by angiotensin-II-amide..", "content": "Acceleration of catecholamine biosynthesis in sympathetically innervated tissues by angiotensin-II-amide.. 1. The effect of angiotensin-II-amide on the biosynthesis of catecholamines (CA) has been studied in a number of isolated tissues in vitro.2. Angiotensin increased the synthesis of CA from (14)C-tyrosine in guinea-pig atria and portal vein, in rat vasa deferentia and the rabbit portal vein.3. Angiotensin had no effect on synthesis of CA from (14)C-labelled DL-DOPA.4. The conditions required to demonstrate an increased synthesis were critical with respect to incubation time and angiotensin concentration. Effects were most readily apparent after incubation for 1 h with concentrations of angiotensin ranging from 10(-9) to 10(-7)M. Higher concentrations caused a significant reduction in synthesis.5. An increased release of newly synthesized CA into the incubation medium was sometimes seen in the presence of angiotensin. However, there was no correlation between increased synthesis and release of CA.6. Angiotensin was rapidly destroyed when incubated with guinea-pig or rat tissues in Krebs solution. The increase in CA synthesis was only apparent at a time when the incubation medium could have contained only a fraction of the original angiotensin activity.7. It is concluded that the effect of angiotensin is not due to increased release of noradrenaline (NA) or to inhibition of NA uptake into nerves. It is possible that angiotensin may influence the activity of tyrosine hydroxylase or its cofactors by an as yet unknown mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346853"}
{"pmid": "4346855", "title": "New virus infections.", "content": "New virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346855"}
{"pmid": "4346854", "title": "A myotoxin secreted by some piscivorous Conus species.", "content": "A myotoxin secreted by some piscivorous Conus species. 1. Toxins isolated from the venom apparatus of Conus magus and Conus achatinus have the same pharmacological properties, but differ from the toxins of several other piscivorous species of cone shells.2. C. magus and C. achatinus toxins are heat labile at pH 8.5. A single lethal component with an approximate molecular weight of 10,000 was isolated from C. achatinus toxin by exclusion chromatography.3. Animals died from a characteristic spastic paralysis after intravenous injection of the toxin.4. Nerve transmission was unaffected by the toxin; skeletal muscle appeared to be the primary site of action. The toxin caused a persistent contracture of rat diaphragm muscle, and a dose-dependent decline in twitch tension. The contracture was potentiated by caffeine.5. The decline in twitch tension was associated with depolarization of the cell membrane. Action potential height and the maximum rate of rise declined, and spike propagation failed when the resting potential had declined to approximately 60 mV. The muscle recovered very slowly on washout of the toxin. The depolarization could be reversed by exposure of the preparation to 5 mM Na(+) solution or tetrodotoxin or saxitoxin.6. Miniature end-plate potential frequency in the rat diaphragm decreased, as did the quantal content of the end-plate potential. The acetylcholine-induced contraction and depolarization of the chronically denervated rat diaphragm were increased by low doses of toxin and reduced by higher, depolarizing toxin doses. The K(+)-induced contraction and depolarization of innervated diaphragm were similarly affected by the toxin.7. Cardiac and smooth muscle were relatively resistant to the toxin. The isotonic contraction of the isolated perfused guinea-pig heart was increased by the toxins from both Conidae. The heart rate decreased. Guinea-pig atrial cells showed a small decrease in action potential height and maximum rate of rise. Rabbit sino-atrial cells showed increases in action potential height, maximum diastolic potential and maximum rate of rise of the spike at low toxin levels, and no change in any of these parameters at high levels. There was a decrease in the rate of the spontaneously beating atrium. Atrioventricular nodal potentials showed no change other than a slight increase in the maximum rate of rise of the action potential.8. It is postulated that the action of the toxin may be related to a change in the Ca(++) permeability of the excitable membrane, which makes it unstable, leading to a secondary, depolarizing entry of Na(+). The effects of the toxin are compared with those of batrachotoxin, which it somewhat resembles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346854"}
{"pmid": "4346856", "title": "Interferon studies with Japanese and U.S. rubella virus strains.", "content": "Interferon studies with Japanese and U.S. rubella virus strains. Japanese strains of rubella virus have been claimed not to be teratogenic, and tests on three Japanese strains showed that they induced high levels of interferon in human placental cell cultures obtained from conceptuses ranging from 13 to 24 weeks' gestational age, whereas two strains derived from the U.S.A. induced low levels. Both Japanese and U.S. strains induced similar but low levels in fetal lung cell cultures and leucocyte preparations. A representative Japanese strain and a U.S. strain were both interferon-sensitive. If indeed a strain can be shown to be non-teratogenic it could lead to an alternative, safer rubella vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346856"}
{"pmid": "4346857", "title": "Whooping cough.", "content": "Whooping cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346857"}
{"pmid": "4346858", "title": "Radiotherapy and carcinoma of the parotid.", "content": "Radiotherapy and carcinoma of the parotid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346858"}
{"pmid": "4346863", "title": "Relation between steroidogenesis and 3',5'-cyclic AMP production in isolated adrenal cells.", "content": "Relation between steroidogenesis and 3',5'-cyclic AMP production in isolated adrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346863"}
{"pmid": "4346864", "title": "Simultaneous determinations of plasma ACTH and GH levels after an oral metyrapone.", "content": "Simultaneous determinations of plasma ACTH and GH levels after an oral metyrapone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346864"}
{"pmid": "4346865", "title": "Results of a clinical trial with intermittent doses of adriamycin in lung cancer.", "content": "Results of a clinical trial with intermittent doses of adriamycin in lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346865"}
{"pmid": "4346866", "title": "Spontaneous immunity to mammary-tumour virus (MTV)-associated antigens in mice and its influence on syngeneic mammary-tumour growth.", "content": "Spontaneous immunity to mammary-tumour virus (MTV)-associated antigens in mice and its influence on syngeneic mammary-tumour growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346866"}
{"pmid": "4346868", "title": "Some investigations concerning the growth characteristics of Entamoeba histolytica in monoxenic association in a new culture medium.", "content": "Some investigations concerning the growth characteristics of Entamoeba histolytica in monoxenic association in a new culture medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346868"}
{"pmid": "4346869", "title": "Ultrastructure of primary human liver cell carcinoma using material already blocked in paraffin.", "content": "Ultrastructure of primary human liver cell carcinoma using material already blocked in paraffin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346869"}
{"pmid": "4346867", "title": "Electronic coupling between neurons in the rat lateral vestibular nucleus.", "content": "Electronic coupling between neurons in the rat lateral vestibular nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346867"}
{"pmid": "4346870", "title": "The effect of malnutrition on human central nervous system myelin.", "content": "The effect of malnutrition on human central nervous system myelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346870"}
{"pmid": "4346871", "title": "Intramedullary spinal cord metastases. Clinical and radiographic findings in nine cases.", "content": "Intramedullary spinal cord metastases. Clinical and radiographic findings in nine cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346871"}
{"pmid": "4346872", "title": "Differentiation of carcinomatous and bacterial meningitis.", "content": "Differentiation of carcinomatous and bacterial meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346872"}
{"pmid": "4346874", "title": "What's your diagnosis? Granular cell myoblastoma.", "content": "What's your diagnosis? Granular cell myoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346874"}
{"pmid": "4346875", "title": "Nonlinear response of the reticuloendothelial system upon stimulation.", "content": "Nonlinear response of the reticuloendothelial system upon stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346875"}
{"pmid": "4346873", "title": "Subacute necrotizing encephalomyelopathy with vacuolated cells in the bone marrow.", "content": "Subacute necrotizing encephalomyelopathy with vacuolated cells in the bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346873"}
{"pmid": "4346877", "title": "The effect of premature weaning on the response of rat adrenals to stress and ACTH.", "content": "The effect of premature weaning on the response of rat adrenals to stress and ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346877"}
{"pmid": "4346879", "title": "Alteration of the relative stability of dA-dT and dG-dC base pairs in DNA.", "content": "Alteration of the relative stability of dA-dT and dG-dC base pairs in DNA. Several small alkylammonium ions can eliminate, or even reverse, the usual dependence of the DNA transition temperature on base composition. For example, in 3 M tetramethylammonium chloride, or 2.4 M tetraethylammonium chloride, DNAs of different base compositions all melt at a common temperature, and with a greatly decreased breadth of transition reflecting only the sequence-independent components of melting cooperativity. At still higher concentrations of such additives, dG.dC-rich DNAs melt at lower temperatures than dA.dT-rich molecules. Circular dichroism spectra show that these additives alter the structure of the DNA double helix very little at room temperature. This differential (base-specific) effect on helix stability is investigated with several small additives related to the tetraalkylammonium ions. Additives larger than tetraethylammonium ion have little differential effect on helix stability. Preferential binding of ions to dA.dT base pairs, requiring fit into a \"groove\" of DNA, is consistent with these data and with equilibrium binding studies. These differential effects can be distinguished from general destabilizing effects, which are independent of specific features of macromolecular conformation or chemistry. Possible experimental uses of this ability to alter the base-composition-dependent components of the stability of the DNA helix are discussed, as well as the insight this phenomenon provides into the molecular basis for the differential stability of dA.dT and dG.dC base pairs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346879"}
{"pmid": "4346881", "title": "Identification of the synthesis of guanosine tetraphosphate (MS I) as insertion of a pyrophosphoryl group into the 3'-position in guanosine 5'-diphosphate.", "content": "Identification of the synthesis of guanosine tetraphosphate (MS I) as insertion of a pyrophosphoryl group into the 3'-position in guanosine 5'-diphosphate. The phosphate transfer system of Haseltine et al., consisting of a ribosomal wash obtained from a stringent strain of Escherichia coli, washed ribosomes, GTP, and ATP, was used to prepare large quantities of guanosine tetra- and pentaphosphates, the magic spot compounds MS I and MS II of Cashel and Gallant. In our hands, the Haseltine et al. system yielded predominantly guanosine tetraphosphate, ppGpp. This system was used exclusively in the described experiments, with ATP labeled with (32)P in the beta- and gamma-positions as donor. The beta-label was found to produce a ppGp⃰p and the gamma-label a ppGpp⃰. Furthermore, [(3)H]GDP + [gamma-(32)P]ATP yielded ppGpp in a (3)H:(32)P ratio of 1:1. The results indicate a transfer of the terminal pyrophosphoryl group of ATP as a unit. \n\nThe position of the transferred pyrophosphoryl was assayed for by preparation of pGp⃰ from ppGp⃰p with Zn(++)-activated inorganic pyrophosphatase from yeast. The pGp⃰ was then assayed with 3'-nucleotidase, which liberated practically all the labeled phosphate. This result indicate that the phosphate transfer from ATP to GDP yields guanosine 5'-diphosphate-3'-diphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346881"}
{"pmid": "4346880", "title": "Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of catalytic and structural properties.", "content": "Fructose 1,6-bisphosphatase: the role of lysosomal enzymes in the modification of catalytic and structural properties. Seasonal variations in the properties of rabbit-liver fructose 1,6-bisphosphatase have now been linked to corresponding changes in the levels of proteolytic activity in the liver extracts. Incubation of native fructose 1,6-bisphosphatase with purified liver lysosomes causes a 3-fold increase in catalytic activity at pH 9.2, with a smaller, and variable, decrease in activity tested at pH 7.5. These changes in catalytic properties are accompanied by the appearance of a smaller subunit, as was previously reported for the enzyme treated with subtilisin. AMP, a negative modulator of fructose bisphosphatase activity, protects against this action of lysosomes. This proteolytic modification of fructose bisphosphatase by lysosomal enzymes may play a role in the modulation of gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346880"}
{"pmid": "4346882", "title": "Appearance in trypsinized normal cells of reactivity with antibody presumably specific for malignant cells.", "content": "Appearance in trypsinized normal cells of reactivity with antibody presumably specific for malignant cells. Trypsinization of normal human diploid cells (WI-38 and MRC 5) resulted in the appearance of complement-fixing reactivity with an immunoglobulin (anti-HeLa G globulin), prepared against a purified HeLa (malignant human) cell antigen (G), which reacts with various malignant human cell lines and tumors but not with certain normal human cells. The presence of receptors in the nonreacting, untrypsinized normal human cells and the specificity of the reactive groups that appeared after trypsinization was established by the fact that the antibody could be completely absorbed with large quantities of packed, untrypsinized human cells but not with similar quantities of either rabbit or guinea-pig kidney tissue-culture cells, which did not react with this antibody either before or after treatment with trypsin. The change produced by trypsinization is thus similar to the previously demonstrated appearance of reactive groups with the same anti-HeLa G globulin in normal human cells at certain times after infection with herpes simplex and vaccinia viruses. The fact that the trypsinized WI-38 cells absorbed more antibody than the same number of cells before trypsinization indicated that trypsinization resulted not only in the appearance of reactivity with antibody but also in a greater concentration of combining receptors, which is unlike the situation with lectins producing agglutinability without an increase in the number of receptors. Moreover, the fact that absorption with trypsinized normal cells removed larger amounts not only of the antibody reacting with the trypsin-treated WI-38 cells but also of antibody that reacts with WI-38 cells infected with herpes simplex virus and with the malignant HEp-2 cells, suggests that the combining groups that emerge after trypsinization of the normal human cells are the same or similar to those present in malignant human cells (HEp 2) and to those that emerge after infection of the normal human cells with herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346882"}
{"pmid": "4346883", "title": "In vitro repression of the transcription of gas operon by purified gal repressor.", "content": "In vitro repression of the transcription of gas operon by purified gal repressor. We have studied the in vitro repression of gal mRNA synthesis by the gal repressor from Escherichia coli. By use of a four-step purification procedure involving chromatography on phosphocellulose, DEAE-cellulose, and an affinity resin, the gal repressor has been purified about 1600-fold from a crude cell extract. The purification was aided by use of a cell extract made after prophage induction of cells lysogenic for bacteriophage lambda that carries the gal repressor gene (galR). The highly purified gal repressor is an effective and specific repressor of in vitro synthesis of gal mRNA with lambda gal DNA as template. Both D-fucose and D-galactose overcome the action of gal repressor; the half-maximal concentrations of D-fucose and D-galactose for overcoming the action of repressor are 1 mM and 0.5 mM, respectively. The repressor fails to repress gal-specific transcription when the gal DNA contains a cis-dominant operator constitutive (O(c)) mutation. We conclude that the gal repressor recognizes the gal operator site and acts by preventing gal transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346883"}
{"pmid": "4346884", "title": "Surface changes in temperature-sensitive Simian virus 40-transformed cells.", "content": "Surface changes in temperature-sensitive Simian virus 40-transformed cells. A binding assay that shows consistent differences in the amounts of tritium-labeled concanavalin A that bind to normal and virally transformed cells was used to study the kinetic changes of cell surface in SV40-transformed 3T3 cells that express the transformed phenotype in a temperature-sensitive manner (tsSV3T3 cells). The increase in concanavalin A binding, which paralleled the appearance of the characteristics of transformed cells, was dependent on the synthesis of cellular DNA. In agreement with the results of binding studies, exponentially growing tsSV3T3 cells agglutinated at much lower lectin titers (concanavalin A as well as wheat-germ agglutinin) at 32 degrees than at 39 degrees .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346884"}
{"pmid": "4346885", "title": "Secretion and extracellular processing of procollagen by cultured human fibroblasts.", "content": "Secretion and extracellular processing of procollagen by cultured human fibroblasts. Cultures of human diploid fibroblasts were labeled with radioactive proline and glycine, and the precursor of collagen (procollagen) in cells and medium was characterized by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. A covalently assembled molecule with the composition (pro alpha1)(2).pro alpha2 (approximate molecular weight, 360,000) appeared intracellularly soon after synthesis of the constituent chains, and could be detected in the medium after 60 min of labeling. The molecule was stabilized by disulfide bonds between cysteine residues in the amino-terminal procollagen peptide sequences of the three chains. Collagenase digested the molecule to peptides of 30,000 molecular weight or less. Limited digestion with pepsin excised nonhelical procollagen peptides, yielding native, triple-helical tropocollagen. Pulse-chase experiments indicated that a peptidase in the medium sequentially excised the nonhelical peptides from the molecule, generating tropocollagen molecules that aggregated as fibers in the cell layer. The excised, nonhelical procollagen peptides contained little or no proline or glycine. Intramolecular bonds of the lysyl aldehyde type were not detected in the secreted molecule, as reduction of the medium always resulted in quantitative recovery of free pro alpha chains in dodecyl sulfate-urea. Lysyl-derived, covalent bonds appeared to form between tropocollagen molecules aggregating in the cell layer. We suggest the term \"pro-tropocollagen\" for the assembled, secreted precursor of collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346885"}
{"pmid": "4346886", "title": "Effect of environmental pH on rescue of Simian virus 40.", "content": "Effect of environmental pH on rescue of Simian virus 40. Rescue of SV40 virus after Sendai virus-mediated fusion of transformed mouse or hamster cell lines with permissive monkey cells was strikingly dependent on pH in the range 6.4-8.8, with a maximum at pH 8.4. The titer of virus recovered at pH 8.4 was 2 logs higher than that at pH 7.6, and 4 logs higher than that at pH 6.4. The pH-sensitive step was neither the number of heterokaryocytes formed, which was essentially the same at pH 7.6 and 8.4, nor the degree of SV40 replication in the monkey cells, which was also unaffected by pH variation in the range 7.2-8.4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346886"}
{"pmid": "4346887", "title": "Phosphorylation of ribosomal proteins by substrate-specific protein kinases from rabbit reticulocytes.", "content": "Phosphorylation of ribosomal proteins by substrate-specific protein kinases from rabbit reticulocytes. Three protein kinase activities have been identified in ribosome-free supernatant from rabbit reticulocytes by DEAE-chromatography. Two of the protein kinase activities have similar substrate specificities, but differ in respect to dependency on cAMP for activation. These kinases preferentially phosphorylate histone, and also phosphorylate identical ribosomal proteins. One protein band in the 40S ribosomal subunit and six protein bands in the 60S subunit are phosphorylated, as demonstrated by Na dodecyl sulfate-polyacrylamide gel electrophoresis and autoradiography. The third kinase activity preferentially phosphorylates casein, instead of histone, and can use both [gamma-(32)P]ATP and [gamma-(32)P]GTP as phosphate donors. This protein kinase activity phosphorylates one protein band in the 40S subunit different from that phosphorylated by the other two kinases and four bands in the 60S subunit, only one of which is coincident with the proteins phosphorylated by the histone-specific activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346887"}
{"pmid": "4346888", "title": "Expression of differentiated functions in hepatoma cell hybrids: alanine aminotransferase.", "content": "Expression of differentiated functions in hepatoma cell hybrids: alanine aminotransferase. The expression of alanine aminotransferase (EC 2.6.1.2), an enzyme that is inducible in the liver, has been examined in somatic hybrid cells formed by crossing well-differentiated rat hepatoma cells with rat diploid epithelial cells, the former characterized by high activity and inducibility of the enzyme, and the latter by the absence of detectable activity. The hybrid cells that contain essentially complete chromosomal sets of the two parents show only very low activity and little inducibility. Among numerous \"segregated\" hybrid subclones, which have lost up to 40% of the chromosomes initially present, several show expression of intermediate levels of enzyme activity and very little inducibility, and two independent subclones are characterized by full re-expression of both baseline and inducible enzyme activity. The electrophoretic mobility of the enzyme from the latter hybrids, from the hepatoma parental cells, and from rat liver is identical. The absence of a correlation between total chromosome number of the hybrid cells and re-expression of alanine aminotransferase suggests that the loss of specific chromosomes is required for re-expression. In these hybrid cells, the re-expression of alanine aminotransferase baseline and inducibility is independent of that of tyrosine aminotransferase inducibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346888"}
{"pmid": "4346890", "title": "Adenosine 3':5'-cyclic monophosphate as a regulator of bacterial transformation.", "content": "Adenosine 3':5'-cyclic monophosphate as a regulator of bacterial transformation. Adenosine 3':5'-cyclic monophosphate added to exponentially growing cells of Hemophilus influenzae strain Rd increases competence for transformation 100- to 10,000-fold. Cyclic AMP added to near-stationary or stationary cells does not increase competence over the high level normally found in the early stationary phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346890"}
{"pmid": "4346889", "title": "RNA-linked short DNA fragments during polyoma replication.", "content": "RNA-linked short DNA fragments during polyoma replication. During in vitro incubation, nuclei from polyoma-infected cells elongate the daughter strands of the replicative intermediate of polyoma DNA. This process is now shown to involve the transient formation of short fragments (4-5 S), a process that is stimulated by the addition of ribonucleoside triphosphates. The presence of stretches of RNA at the 5'-end of short DNA chains was determined from Cs(2)SO(4) equilibrium centrifugation and from the finding that isotope from alpha-(32)P-labeled deoxynucleoside triphosphates was recovered in 2'(3')-ribonucleotides after alkaline hydrolysis. Transfer occurred preferentially with [alpha-(32)P]dCTP as substrate. Starvation for deoxynucleotides by in vivo treatment with hydroxyurea resulted in the accumulation of short fragments that are deficient in RNA. Our results suggest that a late step during the discontinuous synthesis of polyoma DNA is selectively inhibited when deoxynucleotides are in short supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346889"}
{"pmid": "4346892", "title": "Evidence for boundary lipid in membranes.", "content": "Evidence for boundary lipid in membranes. Cytochrome oxidase (EC 1.9.3.1) isolated from beef-heart mitochondria with an appropriate phospholipid content forms vesicular structures. Lipid-protein interactions in this model membrane system were studied with the lipid spin label, 16-doxylstearic acid. As the phospholipid/protein ratio is varied, two spectral components are observed. At low phospholipid/protein ratios (</=0.19 mg of phospholipid per mg of protein) the lipid spin label is highly immobilized. At higher phospholipid content an additional component characteristic of fluid lipid bilayers is evident. By summation of digitalized spectra and subsequent integration it was shown that all composite spectra could be approximated by assuming only two components are present, and that the amount of phospholipid bound to the protein is independent of the extent of the fluid bilayer region. The experimentally determined amount of phospholipid for maximum occupancy of protein-bound sites is about 0.2 mg of phospholipid per 1.0 mg of protein. Calculations show that this ratio is consistent with a single layer of phospholipid surrounding the protein complex. The data are interpreted as evidence for a boundary of immobilized lipid between the hydrophobic protein and adjacent fluid bilayer regions in this membrane model system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346892"}
{"pmid": "4346891", "title": "Solvent proton magnetic relaxation dispersion in solutions of concanavalin A.", "content": "Solvent proton magnetic relaxation dispersion in solutions of concanavalin A. Concanavalin A, a protein isolated from jack beans, exhibits several important biological properties, all of which are related to its ability to bind and precipitate specific polysaccharides. Concanavalin A is a dimer at pH 5.6, and has one transition-metal and one calcium-ion binding site per monomer unit of molecular weight 27,000. Both metal-ion sites must be occupied for the protein to be active. It is of interest to determine the role of the transition metal ion in Concanavalin A and its relationship to the sugar binding activity of the protein. We report the magnetic field and temperature dependences of the spin-lattice magnetic relaxation rates of solvent protons in aqueous solutions of zinc and manganese derivatives of Concanavalin A, and the influence of monosaccharide binding on these rates. The results of a leastsquares fit of the data to the theory, with five adjustable parameters, indicate that there is one rapidly exchanging water molecule ligand on the Mn(2+) ion, with a residence lifetime of 2.5 musec at 25 degrees , and with its protons 0.27 nm (2.7 A) from the Mn(2+) ion. We find that at low magnetic fields (proton Larmor frequencies below about 10 MHz), the correlation time for the dipolar interaction between the Mn(2+) electronic spin moment and the protons on the water ligand is the spin-lattice relaxation time tau(S) of the Mn(2+) moment, but that at higher magnetic fields the correlation time for the dipolar interaction is determined by the Brownian rotational tumbling of the protein, because of the substantial variation of tau(S) with magnetic field. Monosaccharide binding to manganese Concanavalin A has little effect on the relaxation rates of solvent protons, a result that indicates that the sugars do not bind directly to the transition metal in the protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346891"}
{"pmid": "4346893", "title": "Terminal deoxynucleotidyl transferase in a case of childhood acute lymphoblastic leukemia.", "content": "Terminal deoxynucleotidyl transferase in a case of childhood acute lymphoblastic leukemia. Cells from a patient with childhood acute lymphoblastic leukemia contain an apparent DNA polymerase activity that was not found in any other cells except thymus cells. The enzyme has the properties of terminal transferase, an enzyme known to be found in thymocytes. The cells also contain the three major DNA polymerases found in growing cells. The results suggest that these tumor cells arose from a block in the differentiation of thymocytes. Terminal transferase may be a marker for the origin of leukemic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346893"}
{"pmid": "4346894", "title": "Mechanism of interferon uptake in parental and somatic monkey-mouse hybrid cells.", "content": "Mechanism of interferon uptake in parental and somatic monkey-mouse hybrid cells. Dose-response curves of interferons in different sensitive cells are regularly sigmoidal. In somatic monkey-mouse hybrid cells, however, a significant decrease in the slope of the curve for primate interferon was observed, while the dose-response effect was unaltered for mouse interferon. High concentrations of primate interferon were 10- to 100-times less effective in hybrid clones than in parental monkey CV-1 cells; at low concentrations the antiviral effect was 10- to 20-times higher in hybrid clones than in the parental cells. The receptor(s) for primate interferon located on the cell membrane was destroyed by trypsin but not by EDTA. Similarly, acid pH inactivated these receptor sites. We, thus, postulate that the antiviral effect is, at least partially, related to the amount of interferon taken up by the cells. Uptake could be conditioned by active cooperation of two cell-specific factors: a receptor and an activator. The activator might be missing or inactivated for primate interferon in the hybrid cells. We suggest that the putative antiviral protein is not cell-species specific, and that information for its synthesis in the hybrid cells might be located on a mouse rather than a monkey chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346894"}
{"pmid": "4346913", "title": "What's new in surgery. Gynecology and obstetrics.", "content": "What's new in surgery. Gynecology and obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346913"}
{"pmid": "4346914", "title": "Debridement of dermal ulcers with collagenase.", "content": "Debridement of dermal ulcers with collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346914"}
{"pmid": "4346915", "title": "The effect of isomers of DDD on the ACTH-induced steroid output, histology and ultrastructure of the dog adrenal cortex.", "content": "The effect of isomers of DDD on the ACTH-induced steroid output, histology and ultrastructure of the dog adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346915"}
{"pmid": "4346916", "title": "Studies on the mechanism of cystamine prevention of several liver structural and biochemical alterations caused by carbon tetrachloride.", "content": "Studies on the mechanism of cystamine prevention of several liver structural and biochemical alterations caused by carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346916"}
{"pmid": "4346918", "title": "Influence of gonadotrophins and cyclic AMP on carbohydrate and protein metabolism in the immature rat ovary.", "content": "Influence of gonadotrophins and cyclic AMP on carbohydrate and protein metabolism in the immature rat ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346918"}
{"pmid": "4346919", "title": "On the action of tolbutamide in normal man. 3. Interaction of tolbutamide with glucagon, aminophylline and arginine in stimulating insulin response.", "content": "On the action of tolbutamide in normal man. 3. Interaction of tolbutamide with glucagon, aminophylline and arginine in stimulating insulin response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346919"}
{"pmid": "4346920", "title": "Synthesis and biological activity of some 2' derivatives of adenosine 3',5'-cyclic phosphate.", "content": "Synthesis and biological activity of some 2' derivatives of adenosine 3',5'-cyclic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346920"}
{"pmid": "4346921", "title": "Band pattern of the segment-long-spacing form of collagen. Its use in the analysis of primary structure.", "content": "Band pattern of the segment-long-spacing form of collagen. Its use in the analysis of primary structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346921"}
{"pmid": "4346922", "title": "Histidine at the active site of superoxide dismutase.", "content": "Histidine at the active site of superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346922"}
{"pmid": "4346923", "title": "Alkyl isocyanates as active-site-specific reagents for serine proteases. Reaction properties.", "content": "Alkyl isocyanates as active-site-specific reagents for serine proteases. Reaction properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346923"}
{"pmid": "4346924", "title": "Comparison of catalytic units of muscle and liver adenosine 3',5'-monophosphate dependent protein kinases.", "content": "Comparison of catalytic units of muscle and liver adenosine 3',5'-monophosphate dependent protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346924"}
{"pmid": "4346925", "title": "Comparative kinetic study of human pyruvate kinases isolated from adult and fetal livers and from hepatoma.", "content": "Comparative kinetic study of human pyruvate kinases isolated from adult and fetal livers and from hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346925"}
{"pmid": "4346926", "title": "Periodate oxidation and amino-catalyzed elimination of the terminal nucleoside from adenylate or ribonucleic acid. Products of overoxidation.", "content": "Periodate oxidation and amino-catalyzed elimination of the terminal nucleoside from adenylate or ribonucleic acid. Products of overoxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346926"}
{"pmid": "4346927", "title": "Glycosyltransferase and sialic acid levels of normal and transformed cells.", "content": "Glycosyltransferase and sialic acid levels of normal and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346927"}
{"pmid": "4346928", "title": "Chemical synthesis of  -L-fucopyranosyl phosphate and  -L-rhamnopyranosyl phosphate.", "content": "Chemical synthesis of  -L-fucopyranosyl phosphate and  -L-rhamnopyranosyl phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346928"}
{"pmid": "4346930", "title": "A meal of pig.", "content": "A meal of pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346930"}
{"pmid": "4346931", "title": "A- and C-type particles of mouse myeloma cells.", "content": "A- and C-type particles of mouse myeloma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346931"}
{"pmid": "4346932", "title": "Influence of hormones, poly I:C, polyvinylpyrrolidon and  -stimulators on in vitro infection with murine leukemia virus.", "content": "Influence of hormones, poly I:C, polyvinylpyrrolidon and  -stimulators on in vitro infection with murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346932"}
{"pmid": "4346933", "title": "Nearest neighbor frequencies of mitochondrial DNA in spontaneous mouse hepatomas.", "content": "Nearest neighbor frequencies of mitochondrial DNA in spontaneous mouse hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346933"}
{"pmid": "4346934", "title": "Tumours of the peripheral and central nervous system induced in BD-rats by prenatal application of methyl methanesulfonate.", "content": "Tumours of the peripheral and central nervous system induced in BD-rats by prenatal application of methyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346934"}
{"pmid": "4346935", "title": "Resistance to methylene dimethane sulphonate (MDMS) in L1210 cells in vitro.", "content": "Resistance to methylene dimethane sulphonate (MDMS) in L1210 cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346935"}
{"pmid": "4346939", "title": "Plasmaphoresis and plasma exchange in the treatment of hyperlipaemia and xanthomatous neuropathy in patients with primary biliary cirrhosis.", "content": "Plasmaphoresis and plasma exchange in the treatment of hyperlipaemia and xanthomatous neuropathy in patients with primary biliary cirrhosis. Two patients with primary biliary cirrhosis who were increasingly incapacitated by xanthomatous neuropathy are described. Treatment with a low fat diet and cholestyramine was unhelpful but repeated plasmaphoresis by simple venesection in one and plasma exchange using an IBM blood cell separator in the other over a period of several months completely relieved the symptoms of the neuropathy, caused skin xanthomata to recede, and lowered plasma lipid levels in both patients. There was no evidence that this procedure was associated with any deleterious effects on the liver. The size of the cholesterol pool in xanthomata in one patient was estimated to be approximately 35 g, and from the plasma cholesterol response to plasmaphoresis at varying frequency it was suggested that the excess of cholesterol synthesis over degradation was less than 0.3 g/day in one patient and less than 0.4 g/day in the other. On the basis of the response in these patients it is suggested that the turnover rates of lipid pools are relatively slow in biliary cirrhosis and that cholesterol accumulation is more likely to be due to a reduced catabolic rate than to an increased synthetic rate of cholesterol. Plasmaphoresis or plasma exchange are useful methods of treatment for the rare patient afflicted by this resistant and distressing complication of biliary cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346939"}
{"pmid": "4346940", "title": "Health administration offers many opportunities.", "content": "Health administration offers many opportunities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346940"}
{"pmid": "4346941", "title": "Federal health services grants.", "content": "Federal health services grants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346941"}
{"pmid": "4346943", "title": "Arrhenoblastoma in a 12-year-old girl.", "content": "Arrhenoblastoma in a 12-year-old girl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346943"}
{"pmid": "4346944", "title": "Carcinoma of the breast with cartilaginous metaplasia.", "content": "Carcinoma of the breast with cartilaginous metaplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346944"}
{"pmid": "4346945", "title": "Adenine nucleotide mediation of fructolysis and motility in bovine epididymal spermatozoa.", "content": "Adenine nucleotide mediation of fructolysis and motility in bovine epididymal spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346945"}
{"pmid": "4346946", "title": "Affinity column purification of protocollagen proline hydroxylase from chick embryos and further characterization of the enzyme.", "content": "Affinity column purification of protocollagen proline hydroxylase from chick embryos and further characterization of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346946"}
{"pmid": "4346947", "title": "Basic amino acid transport in Escherichia coli. II. Purification and properties of an arginine-specific binding protein.", "content": "Basic amino acid transport in Escherichia coli. II. Purification and properties of an arginine-specific binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346947"}
{"pmid": "4346948", "title": "Hormonal modulation of amino acid transport in rat hepatoma cells in tissue culture.", "content": "Hormonal modulation of amino acid transport in rat hepatoma cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346948"}
{"pmid": "4346949", "title": "Characterization of the interaction of a protein inhibitor with adenosine 3',5'-monophosphate-dependent protein kinases. II. Mechanism of action with the holoenzyme.", "content": "Characterization of the interaction of a protein inhibitor with adenosine 3',5'-monophosphate-dependent protein kinases. II. Mechanism of action with the holoenzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346949"}
{"pmid": "4346950", "title": "Electron spin resonance studies with dioldehydrase. Evidence for radical intermediates in reactions catalyzed by coenzyme B 12.", "content": "Electron spin resonance studies with dioldehydrase. Evidence for radical intermediates in reactions catalyzed by coenzyme B 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346950"}
{"pmid": "4346951", "title": "Separate phosphodiesterases for the hydrolysis of cyclic adenosine 3',5'-monophosphate and cyclic guanosine 3',5'-monophosphate in rat liver.", "content": "Separate phosphodiesterases for the hydrolysis of cyclic adenosine 3',5'-monophosphate and cyclic guanosine 3',5'-monophosphate in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346951"}
{"pmid": "4346952", "title": "Cytochrome c oxidase from bakers' yeast. I. Isolation and properties.", "content": "Cytochrome c oxidase from bakers' yeast. I. Isolation and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346952"}
{"pmid": "4346953", "title": "Cytochrome c oxidase from bakers' yeast. II. Site of translation of the protein components.", "content": "Cytochrome c oxidase from bakers' yeast. II. Site of translation of the protein components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346953"}
{"pmid": "4346954", "title": "Isolation of a protein component of sodium-potassium transport adenosine triphosphatase containing ligand-protected sulfhydryl groups.", "content": "Isolation of a protein component of sodium-potassium transport adenosine triphosphatase containing ligand-protected sulfhydryl groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346954"}
{"pmid": "4346955", "title": "Erythrocyte protein phosphorylation.", "content": "Erythrocyte protein phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346955"}
{"pmid": "4346956", "title": "Association of glyceraldehyde 3-phosphate dehydrogenase with the human erythrocyte membrane. Effect of detergents, trypsin, and adenosine triphosphate.", "content": "Association of glyceraldehyde 3-phosphate dehydrogenase with the human erythrocyte membrane. Effect of detergents, trypsin, and adenosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346956"}
{"pmid": "4346959", "title": "The intermediate in the uridine diphosphate galactose 4-epimerase reaction. Resolution of an apparent ambiguity.", "content": "The intermediate in the uridine diphosphate galactose 4-epimerase reaction. Resolution of an apparent ambiguity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346959"}
{"pmid": "4346958", "title": "Localization of the polyadenylate sequences in messenger ribonucleic acid and in the heterogeneous nuclear ribonucleic acid of HeLa cells.", "content": "Localization of the polyadenylate sequences in messenger ribonucleic acid and in the heterogeneous nuclear ribonucleic acid of HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346958"}
{"pmid": "4346957", "title": "A comparison of the responses of mitochondrial and cytosol histidine-pyruvate aminotransferases to nutritional and hormonal treatments.", "content": "A comparison of the responses of mitochondrial and cytosol histidine-pyruvate aminotransferases to nutritional and hormonal treatments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346957"}
{"pmid": "4346960", "title": "Cyclic adenosine 3',5'-monophosphate-stimulated protein kinase and a substrate associated with cardiac sarcoplasmic reticulum.", "content": "Cyclic adenosine 3',5'-monophosphate-stimulated protein kinase and a substrate associated with cardiac sarcoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346960"}
{"pmid": "4346961", "title": "Treatment of fractures of the radius and ulna with compression plates.", "content": "Treatment of fractures of the radius and ulna with compression plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346961"}
{"pmid": "4346962", "title": "Resolution of dansyl leucine and dansyl isoleucine.", "content": "Resolution of dansyl leucine and dansyl isoleucine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346962"}
{"pmid": "4346963", "title": "Cytochemistry of polymorphonuclear neutrophils in schistosomiasis.", "content": "Cytochemistry of polymorphonuclear neutrophils in schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346963"}
{"pmid": "4346964", "title": "Diagnosis of extrahepatic biliary obstruction in infants by immunochemical detection of LP-X and modified  131 I-Rose Bengal excretion test.", "content": "Diagnosis of extrahepatic biliary obstruction in infants by immunochemical detection of LP-X and modified  131 I-Rose Bengal excretion test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346964"}
{"pmid": "4346967", "title": "Hemobilia.", "content": "Hemobilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346967"}
{"pmid": "4346966", "title": "Properties of strains of Escherichia coli K12 carrying mutant lex-1 and uvrA6 alleles.", "content": "Properties of strains of Escherichia coli K12 carrying mutant lex-1 and uvrA6 alleles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346966"}
{"pmid": "4346969", "title": "Isolated adrenal cortex cells: hypersensitivity to adrenocorticotropic hormone after hypophysectomy.", "content": "Isolated adrenal cortex cells: hypersensitivity to adrenocorticotropic hormone after hypophysectomy. Cells from the adrenals of hypophysectomized rats (up to 28 days after operation) require less adrenocorticotropic hormone to induce one-half maximal rate of production of 3',5'-adenosine monophosphate than do cells from the adrenals of intact rats. A corresponding increase in sensitivity is reflected in the steroidogenic response to adrenocorticotropic hormone up to 2 days after hypophysectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346969"}
{"pmid": "4346970", "title": "Ultrastructure of the outer epithelium of the mantle in the clam Mercenaria mercenaria in relation to calcification of the shell.", "content": "Ultrastructure of the outer epithelium of the mantle in the clam Mercenaria mercenaria in relation to calcification of the shell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346970"}
{"pmid": "4346971", "title": "Adrenal zona glomerulosa after hypophysectomy in the Mongolian gerbil.", "content": "Adrenal zona glomerulosa after hypophysectomy in the Mongolian gerbil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346971"}
{"pmid": "4346973", "title": "Dipyrone for treatment of post-operative pain.", "content": "Dipyrone for treatment of post-operative pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346973"}
{"pmid": "4346974", "title": "Significance of Staphylococcus epidermidis in the clinical laboratory.", "content": "Significance of Staphylococcus epidermidis in the clinical laboratory. Susceptibility to 11 antibiotics was determined for 63 cultures of Staphylococcus aureus and 63 cultures of Staphylococcus epidermidis obtained at random from the clinical laboratory. The incidence of resistance to nine of these antibiotics was greater for S. epidermidis than for S. aureus. Studies of the minimal inhibitory concentration of these cultures to clindamycin showed that 61 cultures of S. aureus were susceptible whereas only 46 cultures of S. epidermidis were susceptible to this antibiotic. Although cultures of S. aureus were more active in the production of seven virulence factors, some cultures of S. epidermidis produced virulence factors. By successive cultivation in increasing concentrations of clindamycin, resistant variants were obtained for 10 cultures of S. aureus and 3 cultures of S. epidermidis. The presence of subinhibitory concentrations of clindamycin inhibited the production of some virulence factors by the resistant variants. In view of the greater resistance of S. epidermidis to antibiotics and its ability to produce virulence factors, its isolation in the clinical laboratory should not be regarded lightly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346974"}
{"pmid": "4346975", "title": "Value of desiccated swabs for streptococcal epidemiology in the field.", "content": "Value of desiccated swabs for streptococcal epidemiology in the field. Streptococcal surveys in foreign countries or remote areas may be greatly enhanced by the use of calcium alginate swabs desiccated in sterile silica gel. Delays of up to 4 weeks before return to a base laboratory are feasible, and the need for fresh media or laboratory facilities in the field may be eliminated. Comparison of direct plating on crystal violet blood agar versus delayed silica gel preservation during surveys in Uganda, Haiti, Colombia, and Miami, Fla., showed no significant loss of positive cultures from skin lesions and suggests that desiccated swabs increase the recovery of bacitracin-sensitive Streptococcus pyogenes (presumptive group A) from throats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346975"}
{"pmid": "4346976", "title": "Three-day assay for human cytomegalovirus applicable to serum neutralization tests.", "content": "Three-day assay for human cytomegalovirus applicable to serum neutralization tests. A fluorescing cell assay (FCA) technique utilizing the indirect fluorescent-antibody method to measure human cytomegalovirus (CMV)-infected cells has been applied to the rapid determination of CMV-neutralizing antibody. Human sera with complement fixation titers to CMV of 1/32 or greater and fluorescein-conjugated rabbit anti-human globulin are the primary and secondary reagents in the fluorescent-antibody test. FCA measured in 3 days the same number of infectious units measured by plaque assay in 2 weeks. FCA and plaque assay yielded identical neutralizing antibody titers to CMV in 20 human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346976"}
{"pmid": "4346977", "title": "Identification of Vibrio cholerae by pyrolysis gas-liquid chromatography.", "content": "Identification of Vibrio cholerae by pyrolysis gas-liquid chromatography. Cholera-like vibrios examined by pyrolysis gas-liquid chromatography could be distinguished from other common aerobic gram-negative bacilli, including oxidase-positive organisms, e.g., Aeromonas. Vibrios in Heiberg group I were subdivided into three types on the basis of differences in one complex in the chromatogram, and these closely corresponded with the identification as classical, El Tor, or \"intermediate\" biotypes of Vibrio cholerae by conventional methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346977"}
{"pmid": "4346978", "title": "Microbiological testing of Skylab foods.", "content": "Microbiological testing of Skylab foods. The Skylab manned space flight program presented unique food microbiology problems. This challenge was successfully met by careful evaluation of the total Skylab food system by considering the nature of Skylab foods, their processing and handling, and Skylab food safety requirements. Some of the unique problems encountered with the Skylab foods involved: extended storage times, variations in storage temperatures, no opportunity to resupply or charge foods after launch of the Skylab Workshop, first use of frozen foods in space, first use of a food-warming device in weightlessness, relatively small size of production lots requiring statistically valid sampling plans, and use of the food as an accurately controlled segment of sophisticated life science experiments. Consideration of all of these situations generated the need for definitive microbiological tests and test limits. These tests are described in this paper along with the rationale for their selection. Test results are reported which show successful compliance with the test limits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346978"}
{"pmid": "4346980", "title": "Serum neutralization tests with infectious bovine rhinotracheitis-infectious pustular vulvovaginitis (IBR-IPV) virus.", "content": "Serum neutralization tests with infectious bovine rhinotracheitis-infectious pustular vulvovaginitis (IBR-IPV) virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346980"}
{"pmid": "4346981", "title": "Characteristics of a paramyxovirus isolated from an aborted bovine fetus.", "content": "Characteristics of a paramyxovirus isolated from an aborted bovine fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346981"}
{"pmid": "4346982", "title": "Japanese encephalitis in horses in Japan.", "content": "Japanese encephalitis in horses in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346982"}
{"pmid": "4346983", "title": "Effects of fasting and diet on enzyme profiles in ovine liver and adipose tissue.", "content": "Effects of fasting and diet on enzyme profiles in ovine liver and adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346983"}
{"pmid": "4346984", "title": "Adrenal response to ACTH in the pig.", "content": "Adrenal response to ACTH in the pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346984"}
{"pmid": "4346985", "title": "Effects of \"soluble silica\" on growth, nutrient balance and reproductive performance of albino rats.", "content": "Effects of \"soluble silica\" on growth, nutrient balance and reproductive performance of albino rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346985"}
{"pmid": "4346986", "title": "Prenatal development, histochemistry and innervation of porcine muscle.", "content": "Prenatal development, histochemistry and innervation of porcine muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346986"}
{"pmid": "4346987", "title": "Innervation of genetically enlarged muscles from double-muscled cattle.", "content": "Innervation of genetically enlarged muscles from double-muscled cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346987"}
{"pmid": "4346988", "title": "The pharmacology and ionic dependency of amino acid responses in the frog spinal cord.", "content": "The pharmacology and ionic dependency of amino acid responses in the frog spinal cord. 1. The isolated frog spinal cord was used to study the action of amino acids and their antagonists on primary afferent terminals and motoneurones. The direct effects of these substances were observed by bathing the cord in 20 mM magnesium sulphate (thus blocking synaptic transmission) and recording the polarization level of the dorsal and ventral roots.2. gamma-Aminobutyric acid (GABA) and glutamic acid depolarized the dorsal root and reduced dorsal-root potentials, while glycine produced only weak and variable effects. Glutamic acid also depolarized the ventral root; GABA usually produced either a hyperpolarization or had little effect, while glycine caused variable effects.3. Bicuculline and picrotoxin antagonized all the synaptic potentials recorded on the dorsal root, as well as the GABA responses on both dorsal and ventral roots.4. All the synaptic potentials examined remained and were markedly prolonged in the absence of external chloride except the ventral root-dorsal root potential. Replacement of the physiologic complement of chloride during chloride-free perfusion restored the potentials to their original time courses.5. Depolarizing amino acid responses remained in the absence of external chloride, while hyperpolarizing responses were reversed into depolarizations. Return to normal Ringer solution re-established the hyperpolarizations.6. Removal of external sodium reversibly abolished the amino acid depolarizations but had little effect on the depolarizations in response to applications of high external potassium concentrations.7. The results support the hypotheses (a) that GABA mediates presynaptic inhibition by depolarizing primary afferent terminals and (b) that the GABA-mediated depolarization is sodium dependent.8. The results also indicate that GABA utilizes different ionic mechanisms to mediate presynaptic inhibition (sodium) and post-synaptic inhibition (chloride) in the amphibian (and presumably in the mammal).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346988"}
{"pmid": "4346989", "title": "Neuromuscular transmission in a mammalian preparation in the absence of blocking drugs and the effect of D-tubocurarine.", "content": "Neuromuscular transmission in a mammalian preparation in the absence of blocking drugs and the effect of D-tubocurarine. 1. Neuromuscular transmission in the presence and absence of D-tubocurarine was examined in cut muscle preparations of the rat diaphragm using intracellular recording techniques. The method of localizing the end-plates is described and evidence is presented indicating that end-plate potential (e.p.p.) recordings were made close to the end-plate region and that reliable estimates of the quantum content of e.p.p.s could be made.2. During repetitive nerve stimulation at rates between 2 and 10 Hz, e.p.p. amplitudes declined in response to the first 6-8 stimuli to reach a plateau level which was maintained for 1500 stimuli. At higher rates of stimulation some 500-700 stimuli were needed before a plateau level of amplitude was reached. It was demonstrated that these amplitude changes reflected similar changes in the quantal release of ACh.3. Tubocurarine in a concentration of 4 x 10(-8) g/ml. had no effect on quantal release but did reduce quantal size. In the presence of tubocurarine, 8 x 10(-8) g/ml., small reductions in the quantum content of the first e.p.p. in response to a train of stimuli and the maintained quantal release were observed. In the presence of tubocurarine 4 x 10(-7) g/ml., the quantum content of the first e.p.p. and the maintained release were further reduced, to the level previously described for curarized preparations. At this concentration a significant effect of tubocurarine upon the presynaptic measurements could be detected (t test). Studies on single junctions revealed that the post- and presynaptic effects of tubocurarine developed with different time courses.4. Neuromuscular preparations in vivo have been reported to be much more resistant to maintatined stimulation than curarized neuromuscular preparations in vitro. It is suggested that this disparity is explained by the presynaptic action of tubocurarine.5. From the quantal release rates of the present investigation and reports of ACh release/stimulus/end-plate in previous investigations it can be calculated that a quantum of ACh contains between 12,000 and 21,000 molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346989"}
{"pmid": "4346991", "title": "Transmitter release by mammalian motor nerve terminals in response to focal polarization.", "content": "Transmitter release by mammalian motor nerve terminals in response to focal polarization. 1. A method is described by which mammalian motor nerve terminals may be uniformly polarized by focally applied current, and the extra-cellular potential in the synaptic cleft, corresponding to any current, estimated.2. The relationship between log m.e.p.p. frequency and local extra-cellular field is flat for hyperpolarization and ascends linearly with depolarization. With depolarization, m.e.p.p. frequency is multiplied about tenfold for every - 18 mV. This characteristic becomes steeper the closer the polarizing electrode to the nerve terminal with a limiting value of ten-fold per - 15 mV.3. There exists a population of small m.e.p.p.s which are generated at the same end-plate as normal m.e.p.p.s.4. Following a prolonged depolarizing pulse there is an increase of m.e.p.p. frequency which continues for periods of up to several minutes.5. With hyperpolarizing pulses m.e.p.p. frequency may increase in a characteristic ;bursty' manner. Similar bursts of m.e.p.p.s also occur spontaneously, but far less frequently, without polarization.6. During a depolarizing pulse, m.e.p.p. frequency becomes maximal or near maximal within 2 sec. There is little subsequent alteration of m.e.p.p. frequency. Numbers of m.e.p.p.s occurring during depolarizing pulses follow the Poisson distribution.7. Following a depolarizing pulse, numbers of m.e.p.p.s released by a subsequent pulse may be either increased or diminished.8. Comparison of the response of m.e.p.p. frequency to raised [K] and to extrinsic presynaptic polarization leads to the conclusion that the presynaptic transmembrane potential change corresponding to any focal current pulse is about two thirds of the local extracellular potential field. Hence the slope of the linear portion of the presynaptic transfer function is about tenfold per 10 mV presynaptic depolarization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346991"}
{"pmid": "4346990", "title": "Synaptic action on Clarke's column neurones in relation to afferent terminal size.", "content": "Synaptic action on Clarke's column neurones in relation to afferent terminal size. 1. Excitatory post-synaptic potentials (e.p.s.p.s) were recorded intracellularly from Clarke's column neurones (DSCT neurones) of the cat in response to adequate stimuli applied to a variety of sensory receptors.2. The amplitude of e.p.s.p.s so produced varied from less than 0.2 mV to more than 2-3 mV. The amplitude distribution of e.p.s.p.s suggested that the mean number of ;quanta' of transmitter released by one impulse varied widely from one fibre to another arising from a given type of sensory receptor.3. The average amplitude of e.p.s.p.s evoked by single afferent impulses was significantly smaller for cutaneous inputs than for muscle or joint inputs. However, synaptic action on DSCT neurones produced by different sensory inputs was equally greater, on the average, than that on spinal motoneurones.4. Both small and large e.p.s.p.s in DSCT neurones failed to increase in amplitude during post-synaptic hyperpolarization applied through the cell body. This failure could not be attributed to possible anomalous rectification in the post-synaptic membrane.5. Small and large e.p.s.p.s were comparable in half-decay time, but there was a positive correlation between amplitude and time-to-peak of e.p.s.p.s. It is suggested that the locations of synapses responsible for small and large e.p.s.p.s are intermingled on the dendrites and that large e.p.s.p.s are associated with a longer duration of transmitter action than small e.p.s.p.s.6. Degenerating terminals of primary afferent fibres on DSCT neurones and motoneurones were examined with the electron microscope after chronic section of the dorsal roots.7. Dendritic degenerating terminals showed no significant difference in size between motoneurones and DSCT neurones. Degenerating ;giant' terminals were found on DSCT neurones, but they were located only on or very close to the cell body.8. It is concluded that the major factor responsible for a large number of ;quanta' of transmitter released at synapses on DSCT neurones is the number of multiple synaptic contacts formed by one afferent fibre rather than the size of individual synapses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346990"}
{"pmid": "4346992", "title": "Cumulative and persistent effects of nerve terminal depolarization on transmitter release.", "content": "Cumulative and persistent effects of nerve terminal depolarization on transmitter release. 1. Following focal depolarization of rat motor nerve terminals there could often be observed an ;after-discharge' of m.e.p.p.s with transient frequencies of up to 1000/sec. This after-discharge was graded with intensity and duration of the previous depolarization.2. Following pulses which were relatively short (about 1 sec) and not too large (< -100 mV local extracellular potential field) the logarithm of m.e.p.p. frequency fell exponentially. With larger or longer pulses there was a tail to the after-discharge which could persist for several minutes.3. M.e.p.p. frequency during an after-discharge was not inhibited appreciably by nerve terminal hyperpolarization, raised [Ca] (8 mM) or lowered pH.4. Measured as a multiplication of spontaneous m.e.p.p. frequency after-discharge was depressed in solution containing no Ca(2+) and added 1 mM-MgEDTA but equal in 0.125 mM-Ca(2+) or 2 mM-Sr(2+) to that in 2 mM-Ca(2+) or 8 mM-Ca(2+).5. During an after-discharge the multiplication of m.e.p.p. frequency by focal nerve terminal depolarization or raised K(+) was reduced. This phenomenon was termed ;uncoupling'.6. It was concluded that the after-discharge is not caused by a persistent rise of K(+) concentration in the synaptic cleft, nor by a maintained nerve terminal depolarization.7. In preparations depolarized by raised K(+) m.e.p.p. frequency during a relatively small focal depolarizing pulse rose continuously, after an initial rapid rise, and after the pulse there was a tail of increased m.e.p.p. frequency. The magnitude of the rise during the pulse and the tail after it were similar on, a logarithmic basis; during both processes the logarithm of m.e.p.p. frequency usually followed (approximately) an exponential time course.8. The relative magnitude of the slow effect of depolarization, as compared with the fast effect, was increased by lowering [Ca] or increasing [Mg], and the slow effect of depolarization in contrast to the fast effect was found to exist in the presence of Ca reduced to about 10(-7)M, but only during pulses. At this [Ca] there was no rapid response to depolarization. At [Ca] about 10(-10)M, there was no response at all of m.e.p.p. frequency to nerve terminal depolarization.9. The results are discussed, and compared with similar data referring to ;facilitation' and ;post-tetanic potentiation'. It is concluded that these and the slow effect of depolarization represent the same phenomenon, a response of the transmitter release system which can be distinguished from the fast response in terms of ionic requirement as well as time course.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346992"}
{"pmid": "4346993", "title": "The specific effect of potassium on transmitter release by motor nerve terminals and its inhibition by calcium.", "content": "The specific effect of potassium on transmitter release by motor nerve terminals and its inhibition by calcium. 1. There exist two distinct effects of potassium on the transmitter release system, one which develops rapidly and another which becomes maximal much more slowly. The fast effect is inhibited by raised Ca(2+), which does not inhibit transmitter release evoked by depolarizing pulses. Thus the fast effect is not secondary to nerve terminal depolarization.2. The fast effect of K(+) was found to consist in an increase in the slope of the linear relation between log m.e.p.p. frequency and nerve terminal depolarization. This effect is complete within a few seconds, is inhibited by raised Ca(2+), and is not produced by prolonged focal or electrotonic depolarization, which instead tends to reduce the slope of log m.e.p.p. frequency vs. depolarization.3. A slope change effect like that of K(+) was not found with ouabain or ethanol, nor did these agents depress the slope change effect of K(+). The specific action of K(+) was not exerted on release evoked in the absence of Ca(2+) by ethanol, chloral hydrate, or raised osmotic pressure.4. It is suggested that the specific action of K(+) is to increase the lability of nerve terminal Ca permeability with respect to depolarization of the nerve terminal membrane, while the slow effect of K(+) simply reflects nerve terminal depolarization, slow to become maximal because of diffusion barriers limiting access of raised K(+) to the Ranvier nodes of motor axons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346993"}
{"pmid": "4346994", "title": "The role of calcium in depolarization-secretion coupling at the motor nerve terminal.", "content": "The role of calcium in depolarization-secretion coupling at the motor nerve terminal. 1. The relation between m.e.p.p. frequency (F) and [Ca] was studied at the mouse neuromuscular junction, at varied concentrations of K(+) and at nerve terminals depolarized by focal depolarization.2. Under all conditions the relation between log F and log [Ca] was sigmoid, with a maximum slope that increased with depolarization or raised [K(+)]. In addition, depolarization or raised K(+) caused a progressive shift of the sigmoid curve upward and to the left (to reduced log [Ca]) and increased the range over which log F could be altered by [Ca].3. Reduction of osmotic pressure changed the relation between log F and log [Ca] in the same way as increase of depolarization, while increase of osmotic pressure did the opposite.4. Raised [Mg] acted in two ways: (a) to shift the curve of log F vs. log [Ca] to the right and (b) to reduce maximum Delta log F/Delta log [Ca] without altering the range of log F sensitive to [Ca].5. The relation between log quantal content of e.p.p.s and log [Ca] was similar to that between log m.e.p.p. frequency and log [Ca].6. Individual nerve terminals varied in both Ca-dependent and Ca-independent fractions of log F; a large Ca-independent portion appears to be associated with a low Ca-dependent portion and vice versa. With large prolonged depolarization the Ca-independent portion was increased, apparently at the expense of the Ca-dependent portion.7. The results of all experiments were summarized in terms of parameters found by fitting the observed log release -log [Ca] curves to two theoretical equations, each derived on the basis of a model: (a) all-or-nothing activation of release probability by Ca-complex(es) and (b) graded activation of release probability by Ca complex(es).8. On the basis of the all-or-nothing model, from which follows alinear relation between F and amounts of Ca complex(es), the number of Ca(2+) atoms that ;cooperate' to mediate release appeared to increase progressively with presynaptic depolarization, to a value of 4 or more with a presynaptic action potential.9. On the basis of the graded activation model, which predicts an exponential relation between F and amount of Ca complex, the number of Ca(2+) atoms that combine with Ca receptor appears to be independent of presynaptic depolarization.10. Various models which could account for the data are discussed. It was concluded that all the data are consistent with a model in which:(i) quantal release probability is continuously graded with the amount of a simple Ca complex (CaX) inside the nerve terminal.(ii) Ca entry is governed by presynaptic membrane potential (increasing exponentially with depolarization) and by the amount of a Ca complex (Ca(2)Y) on or in the membrane.(iii) Mg(2+) competes with Ca(2+) at both receptors, X and Y.(iv) The internal Ca receptor X is also increased by presynaptic depolarization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4346994"}
{"pmid": "4347008", "title": "Melanotic neuroectodermal tumor of infancy.", "content": "Melanotic neuroectodermal tumor of infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347008"}
{"pmid": "4347009", "title": "Congenital cataract and ectopia lentis. An analysis of 152 patients treated in 1943-1967.", "content": "Congenital cataract and ectopia lentis. An analysis of 152 patients treated in 1943-1967.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347009"}
{"pmid": "4347013", "title": "Age-dependent changes in the adenylate cyclase and phosphodiesterase activity of rat erythrocytes.", "content": "Age-dependent changes in the adenylate cyclase and phosphodiesterase activity of rat erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347013"}
{"pmid": "4347014", "title": "Scleroderma.", "content": "Scleroderma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347014"}
{"pmid": "4347022", "title": "Dual viral infections in two dogs.", "content": "Dual viral infections in two dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347022"}
{"pmid": "4347021", "title": "Cytochemical observations on glucose-6-phosphatase, glucosan phosphorylase, glucose-6-phosphate dehydrogenase, and  -glycerophosphate dehydrogenase in chick liver cell cultures infected with Trichomonas vaginalis.", "content": "Cytochemical observations on glucose-6-phosphatase, glucosan phosphorylase, glucose-6-phosphate dehydrogenase, and  -glycerophosphate dehydrogenase in chick liver cell cultures infected with Trichomonas vaginalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347021"}
{"pmid": "4347023", "title": "A bovine herpesvirus associated with a disease of the upper respiratory tract of feedlot cattle.", "content": "A bovine herpesvirus associated with a disease of the upper respiratory tract of feedlot cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347023"}
{"pmid": "4347024", "title": "ACTH and nasal polypi.", "content": "ACTH and nasal polypi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347024"}
{"pmid": "4347025", "title": "The management of tumours of the glomus jugulare.", "content": "The management of tumours of the glomus jugulare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347025"}
{"pmid": "4347026", "title": "Plasma corticosterone level in runt disease.", "content": "Plasma corticosterone level in runt disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347026"}
{"pmid": "4347027", "title": "Pathogenesis of Abelson-virus-induced murine leukemia.", "content": "Pathogenesis of Abelson-virus-induced murine leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347027"}
{"pmid": "4347028", "title": "Cultivation of cells from a fibroma in a rattlesnake, Crotalus horridus.", "content": "Cultivation of cells from a fibroma in a rattlesnake, Crotalus horridus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347028"}
{"pmid": "4347029", "title": "Activation in vitro, by 5-iododeoxyuridine, of a latent virus resembling C-type virus in a human sarcoma cell line.", "content": "Activation in vitro, by 5-iododeoxyuridine, of a latent virus resembling C-type virus in a human sarcoma cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347029"}
{"pmid": "4347031", "title": "Radioiodine-labeled antibody test for the detection of membrane antigens associated with Epstein-Barr virus.", "content": "Radioiodine-labeled antibody test for the detection of membrane antigens associated with Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347031"}
{"pmid": "4347030", "title": "Seroepidemiologic studies of herpesvirus type 2 and carcinoma of the cervix. II. Uganda.", "content": "Seroepidemiologic studies of herpesvirus type 2 and carcinoma of the cervix. II. Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347030"}
{"pmid": "4347032", "title": "Studies with human papilloma virus modeled after known papovavirus systems.", "content": "Studies with human papilloma virus modeled after known papovavirus systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347032"}
{"pmid": "4347033", "title": "Mutation and cancer: a model for Wilms' tumor of the kidney.", "content": "Mutation and cancer: a model for Wilms' tumor of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347033"}
{"pmid": "4347034", "title": "Tumor angiogenesis: a quantitative method for histologic grading.", "content": "Tumor angiogenesis: a quantitative method for histologic grading.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347034"}
{"pmid": "4347035", "title": "Immunologic and virologic studies of a nonproducer tumor induced by murine sarcoma virus (Harvey).", "content": "Immunologic and virologic studies of a nonproducer tumor induced by murine sarcoma virus (Harvey).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347035"}
{"pmid": "4347036", "title": "Enhancing effect of excess topical vitamin A on Rous sarcomas in chickens.", "content": "Enhancing effect of excess topical vitamin A on Rous sarcomas in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347036"}
{"pmid": "4347037", "title": "Inoculation of calves with particles resembling C-type virus from cultures of bovine lymphosarcoma.", "content": "Inoculation of calves with particles resembling C-type virus from cultures of bovine lymphosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347037"}
{"pmid": "4347038", "title": "Lung carcinoma of sheep (Jaagsiekte). 3. Lymph node, blood, and immunoglobulin.", "content": "Lung carcinoma of sheep (Jaagsiekte). 3. Lymph node, blood, and immunoglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347038"}
{"pmid": "4347039", "title": "Demonstration of Herpesvirus saimiri-associated antigens in peripheral lymphocytes from infected marmosets during in vitro cultivation.", "content": "Demonstration of Herpesvirus saimiri-associated antigens in peripheral lymphocytes from infected marmosets during in vitro cultivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347039"}
{"pmid": "4347041", "title": "Serologic evidence for a simian-virus-40-like infection of man.", "content": "Serologic evidence for a simian-virus-40-like infection of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347041"}
{"pmid": "4347040", "title": "Infiltrating duct carcinoma of the mammary gland of a rhesus monkey after administration of an oral contraceptive: a preliminary report.", "content": "Infiltrating duct carcinoma of the mammary gland of a rhesus monkey after administration of an oral contraceptive: a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347040"}
{"pmid": "4347042", "title": "Delayed hypersensitivity to simian virus 40 tumor cells in BALB-c mice demonstrated by a radioisotopic foot-pad assay.", "content": "Delayed hypersensitivity to simian virus 40 tumor cells in BALB-c mice demonstrated by a radioisotopic foot-pad assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347042"}
{"pmid": "4347043", "title": "Effect of vinblastine and colchicine on uptake and release of putative transmitters by synaptosomes and on brain actomyosin-like protein.", "content": "Effect of vinblastine and colchicine on uptake and release of putative transmitters by synaptosomes and on brain actomyosin-like protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347043"}
{"pmid": "4347044", "title": "RNA and DNA in developing retinae: comparison of a normal with the degenerating retinae of C3H mice.", "content": "RNA and DNA in developing retinae: comparison of a normal with the degenerating retinae of C3H mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347044"}
{"pmid": "4347045", "title": "Metabolism of phosphatidylcholine, phosphatidylinositol and palmityl carnitine in synaptosomes from rat brain.", "content": "Metabolism of phosphatidylcholine, phosphatidylinositol and palmityl carnitine in synaptosomes from rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347045"}
{"pmid": "4347046", "title": "Metabolic consequences of ethanol oxidation in brains from mice chronically fed ethanol.", "content": "Metabolic consequences of ethanol oxidation in brains from mice chronically fed ethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347046"}
{"pmid": "4347047", "title": "The measurement of the inorganic phosphate content of brain in the presence of bone fragments.", "content": "The measurement of the inorganic phosphate content of brain in the presence of bone fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347047"}
{"pmid": "4347048", "title": "Accumulation of adenosine 3',5'-monophosphate in brain slices: interaction of local anaesthetics and depolarizing agents.", "content": "Accumulation of adenosine 3',5'-monophosphate in brain slices: interaction of local anaesthetics and depolarizing agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347048"}
{"pmid": "4347049", "title": "Activation of the pathway from locus coeruleus to rat cerebellar Purkinje neurons: pharmacological evidence of noradrenergic central inhibition.", "content": "Activation of the pathway from locus coeruleus to rat cerebellar Purkinje neurons: pharmacological evidence of noradrenergic central inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347049"}
{"pmid": "4347050", "title": "Intrarenal prostaglandin release attenuates the renal vasoconstrictor activity of angiotensin.", "content": "Intrarenal prostaglandin release attenuates the renal vasoconstrictor activity of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347050"}
{"pmid": "4347051", "title": "Dynamics of binding and release of the polymyxin antibiotics by tissues.", "content": "Dynamics of binding and release of the polymyxin antibiotics by tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347051"}
{"pmid": "4347052", "title": "Duration effects of supraliminal electrical stimuli to the tongue.", "content": "Duration effects of supraliminal electrical stimuli to the tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347052"}
{"pmid": "4347053", "title": "An alternative approach to generalized complementarity.", "content": "An alternative approach to generalized complementarity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347053"}
{"pmid": "4347054", "title": "Effects of marijuana smoking on the sleep EEG. Preliminary studies.", "content": "Effects of marijuana smoking on the sleep EEG. Preliminary studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347054"}
{"pmid": "4347057", "title": "Recovery of herpes-simplex virus from human trigeminal ganglions.", "content": "Recovery of herpes-simplex virus from human trigeminal ganglions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347057"}
{"pmid": "4347058", "title": "Tic douloureux: etiology, refined treatment.", "content": "Tic douloureux: etiology, refined treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347058"}
{"pmid": "4347061", "title": "Hypoexcitability of ulnar nerve in patients with normal motor nerve conduction velocities.", "content": "Hypoexcitability of ulnar nerve in patients with normal motor nerve conduction velocities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347061"}
{"pmid": "4347059", "title": "Further observations on subacute denervation and mammalian motor nerve terminal function.", "content": "Further observations on subacute denervation and mammalian motor nerve terminal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347059"}
{"pmid": "4347060", "title": "Neuropsychologic and neurologic follow-up after herpesvirus hominis encephalitis.", "content": "Neuropsychologic and neurologic follow-up after herpesvirus hominis encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347060"}
{"pmid": "4347062", "title": "Recurrence of nonneoplastic thymus after thymectomy for myasthenia gravis. Report of two cases.", "content": "Recurrence of nonneoplastic thymus after thymectomy for myasthenia gravis. Report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347062"}
{"pmid": "4347063", "title": "Cytomegalovirus encephalitis in adults.", "content": "Cytomegalovirus encephalitis in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347063"}
{"pmid": "4347064", "title": "Reduction of sympathetic outflow by central administration of L-DOPA, dopamine and norepinephrine.", "content": "Reduction of sympathetic outflow by central administration of L-DOPA, dopamine and norepinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347064"}
{"pmid": "4347065", "title": "Morphology of the normal liver cell.", "content": "Morphology of the normal liver cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347065"}
{"pmid": "4347066", "title": "Renal failure in advanced liver disease.", "content": "Renal failure in advanced liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347066"}
{"pmid": "4347067", "title": "Hepatitis virology.", "content": "Hepatitis virology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347067"}
{"pmid": "4347068", "title": "Lipoproteins and the liver.", "content": "Lipoproteins and the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347068"}
{"pmid": "4347069", "title": "Red blood cell sodium and potassium concentrations in patients with liver diseases.", "content": "Red blood cell sodium and potassium concentrations in patients with liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347069"}
{"pmid": "4347070", "title": "A method for the extraction, separation and estimation of unconjugated estrone, estradiol-17  and estradiol-17  in plasma.", "content": "A method for the extraction, separation and estimation of unconjugated estrone, estradiol-17  and estradiol-17  in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347070"}
{"pmid": "4347071", "title": "The subcellular localization of the changes in ribonuclease and phosphatase activities of the mouse kidney produced by castration and testosterone.", "content": "The subcellular localization of the changes in ribonuclease and phosphatase activities of the mouse kidney produced by castration and testosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347071"}
{"pmid": "4347075", "title": "Role of cyclic AMP and Ca ++  in mechanical and metabolic events in isometrically contracting vascular smooth muscle.", "content": "Role of cyclic AMP and Ca ++  in mechanical and metabolic events in isometrically contracting vascular smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347075"}
{"pmid": "4347074", "title": "Down's syndrome and malignancy.", "content": "Down's syndrome and malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347074"}
{"pmid": "4347078", "title": "Human brain and platelet cyclic adenosine 3',5'-monophosphate phosphodiesterases: different response to drugs.", "content": "Human brain and platelet cyclic adenosine 3',5'-monophosphate phosphodiesterases: different response to drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347078"}
{"pmid": "4347081", "title": "Adenovirus pneumonia.", "content": "Adenovirus pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347081"}
{"pmid": "4347082", "title": "An outbreak of adenovirus type 7 infection in children in Montreal.", "content": "An outbreak of adenovirus type 7 infection in children in Montreal. Thirteen infants and children with adenovirus type 7 infection proved by virus isolation are described. High fever, cough and dyspnea were the most frequent findings; in infants under 1 year of age wheezing was common. Four patients required artificial ventilation. Lobar collapse, consolidation and hyperinflation were frequent radiologic findings. None of the symptoms responded to antibiotic therapy or bronchodilator drugs. Three patients died (mortality rate of 23%). Pathologic findings were compatible with adenovirus type 7 pneumonia, and were characterized by a necrotizing bronchitis and bronchiolitis, patchy alveolar fibrinopurulent exudate and hyaline membrane formation. Some intra-alveolar epithelial cells showed strikingly abnormal nuclei and rare typical halo-outlined intranuclear inclusions were seen. Only one of eight survivors had evidence of significant chronic chest disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347082"}
{"pmid": "4347086", "title": "The molecular basis of mutagenesis by methyl and ethyl methanesulfonates.", "content": "The molecular basis of mutagenesis by methyl and ethyl methanesulfonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347086"}
{"pmid": "4347085", "title": "Regulation of yeast inorganic-pyrophospphatase activity by divalent cations.", "content": "Regulation of yeast inorganic-pyrophospphatase activity by divalent cations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347085"}
{"pmid": "4347084", "title": "Antineoplastic and immunosuppressive drugs. II. Therapeutic uses.", "content": "Antineoplastic and immunosuppressive drugs. II. Therapeutic uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347084"}
{"pmid": "4347087", "title": "Phosphate transfer between 2,3-biphosphoglycerate and monophosphoglycerate catalyzed by bisphosphoglycerate phosphatase.", "content": "Phosphate transfer between 2,3-biphosphoglycerate and monophosphoglycerate catalyzed by bisphosphoglycerate phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347087"}
{"pmid": "4347088", "title": "The substrate specificity of exonuclease A5.", "content": "The substrate specificity of exonuclease A5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347088"}
{"pmid": "4347089", "title": "Studies of glutamate dehydrogenase. Characterization of histidine residues involved in the activity and association. Photoactivated labelling with pyridoxal 5'-phosphate.", "content": "Studies of glutamate dehydrogenase. Characterization of histidine residues involved in the activity and association. Photoactivated labelling with pyridoxal 5'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347089"}
{"pmid": "4347090", "title": "Studies of glutamate dehydrogenase. Modification with 5-diazo-1H-tetrazole and glyoxal. Importance of two different amino groups for the binding of 2-oxoglutarate and NADH.", "content": "Studies of glutamate dehydrogenase. Modification with 5-diazo-1H-tetrazole and glyoxal. Importance of two different amino groups for the binding of 2-oxoglutarate and NADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347090"}
{"pmid": "4347091", "title": "Biosynthesis of N-acetylneuraminic acid in Morris hepatomas.", "content": "Biosynthesis of N-acetylneuraminic acid in Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347091"}
{"pmid": "4347093", "title": "Inhibition of mitochondrial-protein synthesis in rat small-intestinal epithelium.", "content": "Inhibition of mitochondrial-protein synthesis in rat small-intestinal epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347093"}
{"pmid": "4347092", "title": "Reciprocal induction and repression of serine dehydratase and phosphoglycerate dehydrogenase by proteins and dietary-essential amino acids in rat liver.", "content": "Reciprocal induction and repression of serine dehydratase and phosphoglycerate dehydrogenase by proteins and dietary-essential amino acids in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347092"}
{"pmid": "4347094", "title": "Measurement of plasma renin concentration (PRC) using exogenous substrate and radioimmunoassay.", "content": "Measurement of plasma renin concentration (PRC) using exogenous substrate and radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347094"}
{"pmid": "4347095", "title": "Calcium and phosphorus metabolism parathyroid hormone, calcitonin and bone histology in pseudohypoparathyroidism.", "content": "Calcium and phosphorus metabolism parathyroid hormone, calcitonin and bone histology in pseudohypoparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347095"}
{"pmid": "4347096", "title": "The response to TRH, LH-RH, metyrapone and vasopressin in patients with hypothalamo-pituitary disorders.", "content": "The response to TRH, LH-RH, metyrapone and vasopressin in patients with hypothalamo-pituitary disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347096"}
{"pmid": "4347099", "title": "Column chromatographic determination of polymyxin B sulfate.", "content": "Column chromatographic determination of polymyxin B sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347099"}
{"pmid": "4347098", "title": "Perspectives on policy research.", "content": "Perspectives on policy research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347098"}
{"pmid": "4347101", "title": "The significance of dense core particles in subacute demyelinating disease in an adult.", "content": "The significance of dense core particles in subacute demyelinating disease in an adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347101"}
{"pmid": "4347100", "title": "Auer bodies in acute promyelocytic leukemia. Demonstration of their fine structure and peroxidase localization.", "content": "Auer bodies in acute promyelocytic leukemia. Demonstration of their fine structure and peroxidase localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347100"}
{"pmid": "4347102", "title": "Thoracic duct drainage during lymphangiography.", "content": "Thoracic duct drainage during lymphangiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347102"}
{"pmid": "4347108", "title": "Dynamic anatomy of the ulnar nerve at the elbow.", "content": "Dynamic anatomy of the ulnar nerve at the elbow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347108"}
{"pmid": "4347113", "title": "Vascular patterns in cerebral neoplasms and their differential diagnosis.", "content": "Vascular patterns in cerebral neoplasms and their differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347113"}
{"pmid": "4347112", "title": "The ten most common types of brain tumor.", "content": "The ten most common types of brain tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347112"}
{"pmid": "4347115", "title": "Cystectomy and segmental resection for primary carcinoma of the bladder: experience at Ochsner Clinic 1942-1968.", "content": "Cystectomy and segmental resection for primary carcinoma of the bladder: experience at Ochsner Clinic 1942-1968.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347115"}
{"pmid": "4347114", "title": "The microbial ecology of the activated sludge process.", "content": "The microbial ecology of the activated sludge process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347114"}
{"pmid": "4347117", "title": "Respiratory infections.", "content": "Respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347117"}
{"pmid": "4347118", "title": "A current look at feline lymphoma.", "content": "A current look at feline lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347118"}
{"pmid": "4347120", "title": "Coincidental pulmonary granular cell schwannoma and bronchogenic adenocarcinoma.", "content": "Coincidental pulmonary granular cell schwannoma and bronchogenic adenocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347120"}
{"pmid": "4347121", "title": "Distinctive cytopathic properties of cytomegalovirus recovered from the female genital tract.", "content": "Distinctive cytopathic properties of cytomegalovirus recovered from the female genital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347121"}
{"pmid": "4347122", "title": "Mallory bodies in a case of primary biliary cirrhosis: an ultrastructural and morphogenetic study.", "content": "Mallory bodies in a case of primary biliary cirrhosis: an ultrastructural and morphogenetic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347122"}
{"pmid": "4347123", "title": "The dependence of pancuronium- and d-tubocurarine-induced neuromuscular blockades on alveolar concentrations of halothane and forane.", "content": "The dependence of pancuronium- and d-tubocurarine-induced neuromuscular blockades on alveolar concentrations of halothane and forane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347123"}
{"pmid": "4347124", "title": "Adrenocorticoids and RNA metabolism in kidney. I. Effect of adrenalectomy on RNA turnover in various subcellular fractions of rat kidney.", "content": "Adrenocorticoids and RNA metabolism in kidney. I. Effect of adrenalectomy on RNA turnover in various subcellular fractions of rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347124"}
{"pmid": "4347125", "title": "Stimulation by reticulocyte initiation factors of protein synthesis in a cell-free system from Krebs II ascites cells.", "content": "Stimulation by reticulocyte initiation factors of protein synthesis in a cell-free system from Krebs II ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347125"}
{"pmid": "4347126", "title": "Effect of in vitro histone phosphorylation on template activity of rat liver chromatin.", "content": "Effect of in vitro histone phosphorylation on template activity of rat liver chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347126"}
{"pmid": "4347127", "title": "Synchronous cultures of Chlamydomonas reinhardti. Synthesis of repressed and derepressed phosphatase during the life cycle.", "content": "Synchronous cultures of Chlamydomonas reinhardti. Synthesis of repressed and derepressed phosphatase during the life cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347127"}
{"pmid": "4347128", "title": "Partial purification of cortisol-binding protein from rat liver cytosol and its role in transcription.", "content": "Partial purification of cortisol-binding protein from rat liver cytosol and its role in transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347128"}
{"pmid": "4347130", "title": "Inclusions in human lens capsule and their relationship to senile exfoliation.", "content": "Inclusions in human lens capsule and their relationship to senile exfoliation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347130"}
{"pmid": "4347131", "title": "Isolation of cytochrome c abundant mutant of Candida utilis.", "content": "Isolation of cytochrome c abundant mutant of Candida utilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347131"}
{"pmid": "4347132", "title": "Use of the Du Pont \"automatic clinical analyzer\" in direct determination of lactic acid in plasma stabilized with sodium fluoride.", "content": "Use of the Du Pont \"automatic clinical analyzer\" in direct determination of lactic acid in plasma stabilized with sodium fluoride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347132"}
{"pmid": "4347133", "title": "Radioimmunoassay of serum renin activity and digoxin concentrations, with use of polyethylene glycol to separate free and antibody-bound ligand.", "content": "Radioimmunoassay of serum renin activity and digoxin concentrations, with use of polyethylene glycol to separate free and antibody-bound ligand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347133"}
{"pmid": "4347134", "title": "Use of 3-methyl-2-benzothiazolone hydrazone in an automated colorimetric method for determination of triglycerides in plasma or serum.", "content": "Use of 3-methyl-2-benzothiazolone hydrazone in an automated colorimetric method for determination of triglycerides in plasma or serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347134"}
{"pmid": "4347135", "title": "Speeded simultaneous turbidimetry of cholesterol in  - and pre- -lipoproteins.", "content": "Speeded simultaneous turbidimetry of cholesterol in  - and pre- -lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347135"}
{"pmid": "4347137", "title": "Descending supraspinal effect in tetanus intoxication of the spinal cord.", "content": "Descending supraspinal effect in tetanus intoxication of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347137"}
{"pmid": "4347138", "title": "Invertebrate central neurons: orthograde degeneration and retrograde changes after axonotomy.", "content": "Invertebrate central neurons: orthograde degeneration and retrograde changes after axonotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347138"}
{"pmid": "4347139", "title": "Biochemistry of adenosine triphosphatase activity of avian fast and slow muscle.", "content": "Biochemistry of adenosine triphosphatase activity of avian fast and slow muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347139"}
{"pmid": "4347140", "title": "Hyperpolarization of trigeminal primary afferents evoked by stimulation of lumbar sympathetic trunk and peripheral nerves.", "content": "Hyperpolarization of trigeminal primary afferents evoked by stimulation of lumbar sympathetic trunk and peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347140"}
{"pmid": "4347141", "title": "Ongoing activity in peripheral nerve: interactions between electrical stimulation and ongoing activity.", "content": "Ongoing activity in peripheral nerve: interactions between electrical stimulation and ongoing activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347141"}
{"pmid": "4347143", "title": "Allozyme genotype-environment relationships. I. Variation in natural populations of Drosophila pachea.", "content": "Allozyme genotype-environment relationships. I. Variation in natural populations of Drosophila pachea. Remarkable geographic and seasonal uniformities in gene and genotype frequencies were found for four enzyme loci. Principal component analysis revealed two patterns of allele frequency changes in three of the allozyme loci (Est-b, Est-c and Acph) and one pattern in the Mdh-d locus. These patterns accounted for 90% to 100% of the variability at these loci. Significant positive correlations were obtained between several of the components and the variability in the non-saponifiable and alkaloid fractions of the senita cactus host plant. The genetic variance within a single locality (Guaymas, Mexico) was as great as the variance between all localities sampled. This is interpreted as a local founder effect. The temporary nature of the rotting cactus breeding site, the delayed maturation and the differential maturation rate of females and males are three factors proposed to cause forced outbreeding and counter the local founder effect. A combination of selection resulting from a direct interaction of the genotype and the environment, in addition to migration, is proposed to maintain the uniform gene frequencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347143"}
{"pmid": "4347145", "title": "Mechanisms of the reactions of cytochrome c. II. The rate of reduction of horse-heart ferricytochrome c by chromium(II).", "content": "Mechanisms of the reactions of cytochrome c. II. The rate of reduction of horse-heart ferricytochrome c by chromium(II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347145"}
{"pmid": "4347146", "title": "Reactions of monomeric cobalt-oxygen complexes. I. Thermodynamics of reaction of molecular oxygen with five- and six-coordinate amine complexes of a cobalt porphyrin.", "content": "Reactions of monomeric cobalt-oxygen complexes. I. Thermodynamics of reaction of molecular oxygen with five- and six-coordinate amine complexes of a cobalt porphyrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347146"}
{"pmid": "4347147", "title": "Use of vanadyl(IV) ion as a new spectroscopic probe of metal binding to proteins. Vanadyl insulin.", "content": "Use of vanadyl(IV) ion as a new spectroscopic probe of metal binding to proteins. Vanadyl insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347147"}
{"pmid": "4347149", "title": "Cyclic adenosine 3',5'-monophosphate-dependent protein kinase stimulation of calcium uptake by canine cardiac microsomes.", "content": "Cyclic adenosine 3',5'-monophosphate-dependent protein kinase stimulation of calcium uptake by canine cardiac microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347149"}
{"pmid": "4347148", "title": "Adrenocorticotropins. 44. Total synthesis of the human hormone by the solid-phase method.", "content": "Adrenocorticotropins. 44. Total synthesis of the human hormone by the solid-phase method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347148"}
{"pmid": "4347150", "title": "An electron spin resonance study of radicals produced in the photolysis of  -keto acids and esters.", "content": "An electron spin resonance study of radicals produced in the photolysis of  -keto acids and esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347150"}
{"pmid": "4347155", "title": "Behavior of lambda bacteriophage in nicotinamide adenine dinucleotide deficient Escherichia coli cells.", "content": "Behavior of lambda bacteriophage in nicotinamide adenine dinucleotide deficient Escherichia coli cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347155"}
{"pmid": "4347156", "title": "Further simplification of the serum neutralization test with herpes simplex virus.", "content": "Further simplification of the serum neutralization test with herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347156"}
{"pmid": "4347157", "title": "Various tests in the evaluation of islet cell adenomas.", "content": "Various tests in the evaluation of islet cell adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347157"}
{"pmid": "4347160", "title": "Oxytocin analogs in the analysis of some phases of hormone action.", "content": "Oxytocin analogs in the analysis of some phases of hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347160"}
{"pmid": "4347161", "title": "Estrogen action: an inroad to cell biology.", "content": "Estrogen action: an inroad to cell biology. The literature concerning the mechanism of estrogen action is extensively reviewed and a concept of the mechanism is proposed.  2 recurrent observations in the studies in this area are: 1) cells responsive to estrogen contain a recepter protein (or recepter aggregate) that interacts specifically with structural features of the e strogen molecule forming a high  affinity, noncovalent complex and 2) many of the hormonal responses are dependent on hormonal acceleration of the genetic expression mechanisms in the sensitive cells.  A theory is presented in which estrogen is visualized as a modulator in the class expression of multiple genes through the control of the availability or state of proteins essential in the nuclear scene for expression of these genes.  The conceptual framework provides for both the variation in estr ogenic responses in various target organs.  Following the main body of the article Mueller discusses the concept and related considerations with serveral other researchers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347161"}
{"pmid": "4347163", "title": "Structure, synthesis, and mechanism of action of parathyroid hormone.", "content": "Structure, synthesis, and mechanism of action of parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347163"}
{"pmid": "4347162", "title": "18-Hydroxy-11-deoxycorticosterone (18-OH-DOC) secretion in experimental and human hypertension.", "content": "18-Hydroxy-11-deoxycorticosterone (18-OH-DOC) secretion in experimental and human hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347162"}
{"pmid": "4347165", "title": "Autoregulation of renal blood flow in rabbits immunized with angiotensin II.", "content": "Autoregulation of renal blood flow in rabbits immunized with angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347165"}
{"pmid": "4347166", "title": "Angiotensin. II. Important role in the maintenance of arterial blood pressure.", "content": "Angiotensin. II. Important role in the maintenance of arterial blood pressure. An angiotensin II antagonist, [1-sarcosine, 8-alanine]-angiotensin II, was given intravenously to anesthetized dogs with thoracic caval constriction and ascites to investigate the role of angiotensin II in the control of arterial pressure. The antagonist produced a striking fall in arterial pressure and in aldosterone secretion and an accompanying increase in plasma renin activity. In a control experiment, normal anesthetized dogs were given the angiotensin analog, but it failed to reduce arterial pressure or to influence plasma renin activity. In conscious dogs with caval constriction, the antagonist produced essentially the same drop in arterial pressure as observed in anesthetized animals. These results suggest an important role for angiotensin II in the maintenance of arterial pressure by its action on specific receptor sites in arteriolar smooth muscle and in the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347166"}
{"pmid": "4347167", "title": "Norepinephrine-containing neurons: changes in spontaneous discharge patterns during sleeping and waking.", "content": "Norepinephrine-containing neurons: changes in spontaneous discharge patterns during sleeping and waking. Norepinephrine-containing neurons of the locus coeruleus of the cat were recorded with microelectrodes during unrestrained sleeping and waking. The recorded neurons were subsequently defined by combined fluorescence histochemistry of catecholamines and production of microlesions at recording sites. These pontine units show homogeneous changes in discharge patterns with respect to sleep stages, firing slowly during drowsy periods and slow wave sleep and firing in rapid bursts during paradoxical sleep. These data provide a direct correlation between the activity of defined catecholamine-containing neurons and the spontaneous occurrence of sleep stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347167"}
{"pmid": "4347168", "title": "Proton beam radiography in tumor detection.", "content": "Proton beam radiography in tumor detection. Monoenergetic protons are highly sensitive to density variations and are capable of giving radiographs of very high contrast. As an initial step in exploring their diagnostic potential, protons with energies of 160 million electron volts are used in \"contact radiography\" on tumor-bearing human brain specimens. The proton radiographs are compared with x-radiographs taken under identical specimen conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347168"}
{"pmid": "4347169", "title": "Synthesis of infective poliovirus in BSC-1 monkey cells enucleated with cytochalasin B.", "content": "Synthesis of infective poliovirus in BSC-1 monkey cells enucleated with cytochalasin B. BSC-1 monkey kidney cells were enucleated by two cycles of centrifugation in the presence of cytochalasin B. The resulting populations contained 99.5 percent enucleated cells. After infection, newly synthesized poliovirus was recovered from the enucleated populations. Final virus yield per enucleated cell was about one-fifth the yield per infected untreated cell", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347169"}
{"pmid": "4347170", "title": "Cylic AMP. A mediator of hormone response and its clinical application.", "content": "Cylic AMP. A mediator of hormone response and its clinical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347170"}
{"pmid": "4347174", "title": "Changes in net hydration of DNA during thermal helix-coil transition.", "content": "Changes in net hydration of DNA during thermal helix-coil transition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347174"}
{"pmid": "4347176", "title": "New federal legislation on alcoholism--opportunities and problems.", "content": "New federal legislation on alcoholism--opportunities and problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347176"}
{"pmid": "4347175", "title": "Assay for the intactness of the outer membrane in isolated mitochondria.", "content": "Assay for the intactness of the outer membrane in isolated mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347175"}
{"pmid": "4347177", "title": "Interconvertible and noninterconvertible forms of rat pyruvate kinase.", "content": "Interconvertible and noninterconvertible forms of rat pyruvate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347177"}
{"pmid": "4347178", "title": "Characterization of two forms of beef heart cyclic nucleotide phosphodiesterase.", "content": "Characterization of two forms of beef heart cyclic nucleotide phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347178"}
{"pmid": "4347179", "title": "Xanthine oxidase catalyzed oxidation of aldehydes. Oxidation of aliphatic aldehydes and 2- and 4-pyridinecarboxaldehyde.", "content": "Xanthine oxidase catalyzed oxidation of aldehydes. Oxidation of aliphatic aldehydes and 2- and 4-pyridinecarboxaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347179"}
{"pmid": "4347180", "title": "Effect of spermidine on the activity of DNA polymerases.", "content": "Effect of spermidine on the activity of DNA polymerases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347180"}
{"pmid": "4347181", "title": "Terminal nucleotides of avian myeloblastosis virus RNA and of ribosomal RNA from chicken leukemic myeloblasts.", "content": "Terminal nucleotides of avian myeloblastosis virus RNA and of ribosomal RNA from chicken leukemic myeloblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347181"}
{"pmid": "4347188", "title": "Retroperitoneal xanthogranuloma and xanthosarcoma (malignant fibrous xanthoma).", "content": "Retroperitoneal xanthogranuloma and xanthosarcoma (malignant fibrous xanthoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347188"}
{"pmid": "4347187", "title": "Some systemic effects of malignant tumors. I. Co-enzyme A levels.", "content": "Some systemic effects of malignant tumors. I. Co-enzyme A levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347187"}
{"pmid": "4347189", "title": "Leiomyomatous hamartoma of the kidney. A clinical and pathologic analysis of 20 cases from the Kidney Tumor Registry.", "content": "Leiomyomatous hamartoma of the kidney. A clinical and pathologic analysis of 20 cases from the Kidney Tumor Registry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347189"}
{"pmid": "4347190", "title": "Intrahepatic bile duct carcinoma and C. sinensis infection in Hong Kong.", "content": "Intrahepatic bile duct carcinoma and C. sinensis infection in Hong Kong.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347190"}
{"pmid": "4347192", "title": "Heterogeneity of human serum high-density lipoprotein (HDL 2 ).", "content": "Heterogeneity of human serum high-density lipoprotein (HDL 2 ).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347192"}
{"pmid": "4347193", "title": "The amino acid sequence of bat (Miniopteris schreibersi) cytochrome C.", "content": "The amino acid sequence of bat (Miniopteris schreibersi) cytochrome C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347193"}
{"pmid": "4347195", "title": "Effect of morphine on bradykinin-induced unitary discharges in the spinal cord of the rabbit.", "content": "Effect of morphine on bradykinin-induced unitary discharges in the spinal cord of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347195"}
{"pmid": "4347196", "title": "The use of estrogen antagonists in hormone receptor studies.", "content": "The use of estrogen antagonists in hormone receptor studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347196"}
{"pmid": "4347197", "title": "A critique on the evaluation and mode of action of antiestrogens.", "content": "A critique on the evaluation and mode of action of antiestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347197"}
{"pmid": "4347198", "title": "Estrogens and antiestrogens.", "content": "Estrogens and antiestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347198"}
{"pmid": "4347200", "title": "Effect of antiestrogens on uterine estradiol receptors.", "content": "Effect of antiestrogens on uterine estradiol receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347200"}
{"pmid": "4347199", "title": "Oestrogen uptake by the central nervous system.", "content": "Oestrogen uptake by the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347199"}
{"pmid": "4347203", "title": "Studies on carcinoembryonic antigen.", "content": "Studies on carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347203"}
{"pmid": "4347201", "title": "Aspects on the mode of action of antiestrogens and antiprogestogens.", "content": "Aspects on the mode of action of antiestrogens and antiprogestogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347201"}
{"pmid": "4347202", "title": "Changes in 5-hydroxytryptamine metabolism during anaphylactic shock in rats.", "content": "Changes in 5-hydroxytryptamine metabolism during anaphylactic shock in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347202"}
{"pmid": "4347205", "title": "Adenosine 3',5'-cyclic monophosphate in Chlamydomonas reinhardtii. Influence on flagellar function and regeneration.", "content": "Adenosine 3',5'-cyclic monophosphate in Chlamydomonas reinhardtii. Influence on flagellar function and regeneration. Adenosine 3',5'-cyclic monophosphate (cAMP) influences both flagellar function and flagellar regeneration in Chlamydomonas reinhardtii. The methylxanthine, aminophylline, which can cause a tenfold increase in cAMP level in C. reinhardtii, inhibits flagellar movement and flagellar regeneration by wild-type cells, without inhibiting cell multiplication. Caffeine, a closely related inhibitor, also inhibits flagellar movement and regeneration, but it inhibits cell multiplication too. Regeneration by a mutant lacking the central pair of flagellar microtubules was found to be more sensitive than wild type to inhibition by caffeine and to be subject to synergistic inhibition by aminophylline plus dibutyryl cAMP. Regeneration by three out of seven mutants with different flagellar abnormalities was more sensitive than wild type to these inhibitors. We interpret these results to mean that cAMP affects a component of the flagellum directly or indirectly, and that the responsiveness of that component to cAMP is enhanced by mutations which affect the integrity of the flagellum. The component in question could be microtubule protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347205"}
{"pmid": "4347204", "title": "Lysosomal phospholipase A 1  and A 2  of normal and bacillus calmette guerin-induced alveolar macrophages.", "content": "Lysosomal phospholipase A 1  and A 2  of normal and bacillus calmette guerin-induced alveolar macrophages. A single intravenous injection of 0.1 mg of heat-killed Bacillus Calmette Guérin (BCG) in 0.1 ml of Bayol F produced an accumulation of activated alveolar macrophages (BCG induced). Cells were collected 3.5-4.0 wk after injection. Phospholipases A and three lysosomal marker enzymes (acid phosphatase, beta-glucuronidase, and lysozyme) were measured in homogenates, and the distribution of the phospholipases A and lysosomal, mitochondrial, and microsomal marker enzymes were examined after sucrose gradient centrifugation of a postnuclear (1,000 g) supernatant. Homogenates of normal and BCG-induced macrophages contained phospholipases A(1) and A(2) which had optimal activity at pH 4.0 in the presence of 2.0 mM ethylenediaminetetraacetate (EDTA). These activities were inhibited 50-70% by 2.0 mM CaCl(2). Homogenates of BCG-induced macrophages had specific activities of beta-glucuronidase, acid phosphatase, and lysozyme, which were increased 1.5- to 3.0-fold over the controls, whether expressed as activity per mg protein or activity per 10(7) cells. The specific activities of the phospholipases A, on the other hand, were consistently lower than those of the control. Distribution of the phospholipases A and the lysosomal marker enzymes after sucrose gradient centrifugation suggested that the phospholipases A active at pH 4.0 in the presence of EDTA are of lysosomal origin since: (a) BCG treatment caused a selective increase in the density of particles which contained both the phospholipases A and three lysosomal marker enzymes; and (b) since the density of mitochondria and microsomes were not affected by BCG treatment. The increase in the density of lysosomes seen here may be related to previously described morphologic changes of BCG-induced alveolar macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347204"}
{"pmid": "4347206", "title": "Evidence for pleiotropic changes in lines of Chinese hamster ovary cells resistant to concanavalin A and phytohemagglutinin-P.", "content": "Evidence for pleiotropic changes in lines of Chinese hamster ovary cells resistant to concanavalin A and phytohemagglutinin-P. Lines of Chinese hamster ovary cells resistant to the lectins concanavalin A (Con A) and phytohemagglutinin-P (PHA-P) have been isolated and characterized. Lines were isolated by a stepwise, a single-step, or a cycling single-step procedure, from both mutagen-treated and untreated cultures. The resistant lines showed a higher efficiency of colony formation in the presence of the appropriate lectin than did the wild-type parental line. The cell lines resistant to Con A did not exhibit any detectable cross resistance to PHA-P, nor did the PHA-resistant cells exhibit cross resistance to Con A. The toxicity of Con A from the wild-type and Con A-resistant lines was reduced in the presence of methyl alpha-D-glucopyranoside; this effect was not seen with the PHA-resistant line. Using (125)I-labeled Con A, it was found that Con A was bound preferentially to the surface of intact cells, and that the amount of labeled Con A bound to intact cells was similar for the wild-type and lectin-resistant lines. The Con A-resistant lines were found to be more susceptible to the toxic effects of a number of different compounds, including cyclic AMP and its dibutyryl derivative, sodium butyrate, high concentrations of glucose, phenethyl alcohol, phenol, ouabain, and testosterone. It appears that, in these lines, acquisition of resistance to Con A gave rise to pleiotropic effects which were detected by changes in the sensitivity of the cells to a variety of agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347206"}
{"pmid": "4347208", "title": "The effects of secretagogues on the incorporation of (2- 3 H)myoinositol into lipid in cytological fractions in the pancreas of the guinea pig in vivo.", "content": "The effects of secretagogues on the incorporation of (2- 3 H)myoinositol into lipid in cytological fractions in the pancreas of the guinea pig in vivo. Stimulation of enzyme secretion in the pancreas on injection of a single dose of the cholinergic drug, pilocarpine, was associated with an increased incorporation of [2-(3)H]myoinositol into a lipid, which was previously characterized as phosphatidylinositol. Stimulation of enzyme secretion by hourly injection of the pancreozymin congener, caerulein, led to more increased phosphatidylinositol synthesis than with a single injection of pilocarpine. The amylase level of the pancreas remained at a low level as long as caerulein was injected, indicating continued stimulation of enzyme secretion even though increased phosphatidylinositol synthesis ceased after 6 h. Feeding gave the same stimulation of phosphatidylinositol synthesis as caerulein. The major synthesis of phosphatidylinositol in controls and the stimulation of phosphatidylinositol synthesis by pilocarpine was entirely confined to the microsome fraction throughout the experiments (up to 18 h). This shows that there is no flow of microsomal membrane (smooth- or rough-surfaced endoplasmic reticulum) to other membranous structures throughout the secretory cycle and beyond. It is concluded that the stimulation of phosphatidylinositol synthesis by pancreatic secretagogues is confined to microsomal elements and does not play any role in membrane flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347208"}
{"pmid": "4347207", "title": "Fine structure of nerve fibers and growth cones of isolated sympathetic neurons in culture.", "content": "Fine structure of nerve fibers and growth cones of isolated sympathetic neurons in culture. The leading tips of elongating nerve fibers are enlarged into \"growth cones\" which are seen in tissue culture to continually undergo changes in conformation and to foster numerous transitory slender extensions (filopodia) and/or a veillike ruffling sheet. After explantation of 1-day-old rat superior cervical ganglia (as pieces or as individual neurons), nerve fibers and tips were photographed during growth and through the initial stages of aldehyde fixation and then relocated after embedding in plastic. Electron microscopy of serially sectioned tips revealed the following. The moving parts of the cone, the peripheral flange and filopodia, contained a distinctive apparently filamentous feltwork from which all organelles except membranous structures were excluded; microtubules were notably absent from these areas. The cone interior contained varied forms of agranular endoplasmic reticulum, vacuoles, vesicles, coated vesicles, mitochondria, microtubules, and occasional neurofilaments and polysomes. Dense-cored vesicles and lysosomal structures were also present and appeared to be formed locally, at least in part from reticulum. The possible roles of the various forms of agranular membranous components are discussed and it is suggested that structures involved in both the assembly and degradation of membrane are present in the cone. The content of these growing tips resembles that in sensory neuron growth cones studied by others.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347207"}
{"pmid": "4347209", "title": "Expression of the mitochondrial genome in HeLa cells. IX. Effect of inhibition of mitochondrial protein synthesis on mitochondrial formation.", "content": "Expression of the mitochondrial genome in HeLa cells. IX. Effect of inhibition of mitochondrial protein synthesis on mitochondrial formation. The effect of selective inhibition of mitochondrial protein synthesis by chloramphenicol at 40 or 200 microg/ml on the formation of mitochondria in HeLa cells was investigated. HeLa cells, under the conditions used in the present work, grow at a decreasing rate for at least four cell generations in the presence of 40 microg/ml chloramphenicol, and for two generations in the presence of 200 microg/ml chloramphenicol. The progressive cell growth inhibition which begins after 2 days of exposure of the cells to 40 microg/ml chloramphenicol is immediately or gradually reversible, upon removal of the drug, for periods up to at least 8 days of treatment, though there is a progressive loss of cloning efficiency. In cells which have been treated for 6-7 days with 40 or 200 microg/ml of chloramphenicol, mitochondrial protein synthesis occurs at a normal or near-normal rate 1 h after removal of the drug. Mitochondria increase normally in number and show a normal size and amount of cristae in the presence of either concentration of drug. However, in 4-5% of the mitochondrial profiles the cristae appear to be arranged in unusual, circular, looped or whorled configuration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347209"}
{"pmid": "4347210", "title": "Mode of mitochondrial formation in HeLa cells.", "content": "Mode of mitochondrial formation in HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347210"}
{"pmid": "4347211", "title": "Interferon: effect on the saturation density to which mouse cells will grow in vitro.", "content": "Interferon: effect on the saturation density to which mouse cells will grow in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347211"}
{"pmid": "4347212", "title": "A labyrinthine structure formed from a transverse tubule of mouse ventricular myocardium.", "content": "A labyrinthine structure formed from a transverse tubule of mouse ventricular myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347212"}
{"pmid": "4347213", "title": "Phenobarbital-induced, membrane-like scrolls in the oenocytes of Musca domestica linnaeus.", "content": "Phenobarbital-induced, membrane-like scrolls in the oenocytes of Musca domestica linnaeus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347213"}
{"pmid": "4347215", "title": "Influence of niacinamide administration on brain 5-HT and a possible mode of action.", "content": "Influence of niacinamide administration on brain 5-HT and a possible mode of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347215"}
{"pmid": "4347214", "title": "Angiotensin effect on uptake of norepinephrine by synaptosomes.", "content": "Angiotensin effect on uptake of norepinephrine by synaptosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347214"}
{"pmid": "4347216", "title": "The effects of acetaldehyde on the kinetics of the energy-dependent phosphate-induced swelling of rat liver mitochondria.", "content": "The effects of acetaldehyde on the kinetics of the energy-dependent phosphate-induced swelling of rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347216"}
{"pmid": "4347220", "title": "Potency disturbances following Abrodil myelography.", "content": "Potency disturbances following Abrodil myelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347220"}
{"pmid": "4347221", "title": "Nursing care study; carcinoma of the stomach complicated by metastases.", "content": "Nursing care study; carcinoma of the stomach complicated by metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347221"}
{"pmid": "4347224", "title": "Vitamin C and respiratory infections.", "content": "Vitamin C and respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347224"}
{"pmid": "4347223", "title": "Toxic effect of the fruit of Passiflora adenopoda D. C. on humans: phytochemical determination.", "content": "Toxic effect of the fruit of Passiflora adenopoda D. C. on humans: phytochemical determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347223"}
{"pmid": "4347226", "title": "The phosphorylation of 3'-deoxy-3'-fluorothymidine and its incorporation into DNA in a cellfree system from tumor cells.", "content": "The phosphorylation of 3'-deoxy-3'-fluorothymidine and its incorporation into DNA in a cellfree system from tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347226"}
{"pmid": "4347228", "title": "Study on the intracellular mechanism of LH release in the anterior pituitary.", "content": "Study on the intracellular mechanism of LH release in the anterior pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347228"}
{"pmid": "4347229", "title": "Diagnosis and management of insulinoma.", "content": "Diagnosis and management of insulinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347229"}
{"pmid": "4347230", "title": "Quantitative gas chromatographic analysis of amino acids on a short glass capillary column.", "content": "Quantitative gas chromatographic analysis of amino acids on a short glass capillary column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347230"}
{"pmid": "4347232", "title": "Release of aminoacyl transfer ribonucleic acid from transfer ribonucleic acid synthetase studied by rapid molecular sieve chromatography.", "content": "Release of aminoacyl transfer ribonucleic acid from transfer ribonucleic acid synthetase studied by rapid molecular sieve chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347232"}
{"pmid": "4347231", "title": "Fractionation of microbial DNA strands on poly I-coated kieselguhr.", "content": "Fractionation of microbial DNA strands on poly I-coated kieselguhr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347231"}
{"pmid": "4347236", "title": "Clinical course and complications in Hodgkin's disease.", "content": "Clinical course and complications in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347236"}
{"pmid": "4347237", "title": "The binding of hydrogen and calcium ions by Tamm-Horsfall glycoprotein.", "content": "The binding of hydrogen and calcium ions by Tamm-Horsfall glycoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347237"}
{"pmid": "4347238", "title": "A study of the cystine-containing apolipoprotein of human plasma high density lipoproteins: characterization of cyanogen bromide and tryptic fragments.", "content": "A study of the cystine-containing apolipoprotein of human plasma high density lipoproteins: characterization of cyanogen bromide and tryptic fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347238"}
{"pmid": "4347239", "title": "Backbone folding of immunoglobulin light and heavy chains: a comparison of predicted  -bend positions.", "content": "Backbone folding of immunoglobulin light and heavy chains: a comparison of predicted  -bend positions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347239"}
{"pmid": "4347242", "title": "The effect of compound F6066 on rat luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release in vitro.", "content": "The effect of compound F6066 on rat luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347242"}
{"pmid": "4347243", "title": "Distribution and binding of J 131 -human chorionic gonadotropin (HCG) in different organs of pseudopregnant female rats.", "content": "Distribution and binding of J 131 -human chorionic gonadotropin (HCG) in different organs of pseudopregnant female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347243"}
{"pmid": "4347245", "title": "Ultraviolet-sensitive mutator mutU4 of Escherichia coli inviable with polA.", "content": "Ultraviolet-sensitive mutator mutU4 of Escherichia coli inviable with polA. Attempts to transduce the ultraviolet-sensitive mutator lesion mutU4 into strains deficient in deoxyribonucleic acid polymerase I (polA) were unsuccessful. Mutator recombinants were found when the polA recipient had first been reverted to Pol(+) by selection for resistance to methyl methanesulfonate. The inviability of the mutU4 polA double mutant was demonstrated by a reduction in the absolute number of transductants when the recipient was polA as compared with Pol(+), and selection was made for markers very close to mutU4. Double mutants containing mutU4 and polA4, which determines a cold-sensitive polymerase, were unable to grow at 24 C, the nonpermissive temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347245"}
{"pmid": "4347246", "title": "Spin-labeling studies on the membrane of a facultative thermophilic bacillus.", "content": "Spin-labeling studies on the membrane of a facultative thermophilic bacillus. Spin-labeling studies were conducted to elucidate the rigidity and viscosity of the membrane of a facultative thermophilic bacillus. By employing nitroxide stearate probes, it was observed that this fatty acid was incorporated into the membrane fraction. Electron spin resonance spectroscopy indicated that cells grown at 55 C contained a membrane which was more rigid and viscous than the membrane from cells grown at 37 C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347246"}
{"pmid": "4347248", "title": "A new crystal-containing cell in human adrenal cortex.", "content": "A new crystal-containing cell in human adrenal cortex. Electron microscope examination of the adrenal cortex from three male human subjects revealed a special type of cell occurring in periendothelial spaces, in all adrenal cortex zones. It is a clear, spindle-shaped cell the principal cytoplasmic features of which are crystalline inclusions with a structure similar to that of the Reinke crystals of human testicular interstitial cells and an abundance of microfilaments. Enzymatic digestions with pronase, pepsin, and ribonuclease were performed, and no digestion of the crystals was obtained. The crystals had no peroxidase or acid phosphatase activities. This cell appears to be exclusive to human males and it may be related to adrenal androgen secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347248"}
{"pmid": "4347247", "title": "Comparative transport activity of intact cells, membrane vesicles, and mesosomes of Bacillus licheniformis.", "content": "Comparative transport activity of intact cells, membrane vesicles, and mesosomes of Bacillus licheniformis. Sodium ion was shown to stimulate strongly the transport of l-glutamic acid into cells of Bacillus licheniformis 6346 His(-). Lithium ion had a slight capacity to replace Na(+) in this capacity, but K(+) was without effect. Three of five amino acids tested. l-glutamic acid, l-aspartic acid, and l-alanine, were concentrated against a gradient in the cells. Intracellular pools of these amino acids were extractable with 5% trichloroacetic acid. Pools of l-histidine and l-lysine could not be detected. No evidence of active transport of lysine into cells could be detected, and histidine was taken up in the absence of chloramphenicol but not in its presence. The uptake of glutamic acid by membrane vesicle preparations was strongly stimulated by reduced nicotinamide adenine dinucleotide (NADH) and to a lesser extent by succinate. The presence of phenazine methosulfate increased uptake in the presence of succinate. Either l- or d-lactate and adenosine triphosphate were without effect. None of these compounds stimulated the uptake of glutamic acid by mesosomes, although some mesosome preparations contained separable membrane which was very active. NADH strongly stimulated the uptake of aspartic acid and alanine by membrane vesicles but had only a slight effect on the uptake of histidine and lysine. No evidence of active transport of any of the amino acids into mesosomes could be detected either in the presence or absence of NADH. NADH stimulation of the uptake of glutamic acid by membrane vesicles was destroyed by exposure to light of 360 nm; this inactivation was reversible by vitamin K(2(5)) or K(2(10)). Sodium ion stimulated transport of glutamic acid by membrane vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347247"}
{"pmid": "4347249", "title": "Thymidine transport by cultured Novikoff hepatoma cells and uptake by simple diffusion and relationship to incorporation into deoxyribonucleic acid.", "content": "Thymidine transport by cultured Novikoff hepatoma cells and uptake by simple diffusion and relationship to incorporation into deoxyribonucleic acid. The initial rate of thymidine-(3)H incorporation into the acid-soluble pool by cultured Novikoff rat hepatoma cells was investigated as a function of the thymidine concentration in the medium. Below, but not above 2 microM, thymidine incorporation followed normal Michaelis-Menten kinetics at 22 degrees , 27 degrees , 32 degrees , and 37 degrees C with an apparent K(m) of 0.5 microM, and the V(max) values increased with an average Q(10) of 1.8 with an increase in temperature. The intracellular acid-soluble (3)H was associated solely with thymine nucleotides (mainly deoxythymidine triphosphate [dTTP]). Between 2 and 200 microM, on the other hand, the initial rate of thymidine incorporation increased linearly with an increase in thymidine concentration in the medium and was about the same at all four temperatures. Pretreatment of the cells with 40 or 100 microMp-chloromercuribenzoate for 15 min or heat-shock (49.5 degrees C, 5 min) markedly reduced the saturable component of uptake without affecting the unsaturable component or the phosphorylation of thymidine. The effect of p-chloromercuribenzoate was readily reversed by incubating the cells in the presence of dithiothreitol. Persantin and uridine competitively inhibited thymidine incorporation into the acid-soluble pool without inhibiting thymidine phosphorylation. At concentrations below 2 microM, thymidine incorporation into DNA also followed normal Michaelis-Menten kinetics and was inhibited in an apparently competitive manner by Persantin and uridine. The apparent K(m) and K(i) values were about the same as those for thymidine incorporation into the nucleotide pool. The over-all results indicate that uptake is the rate-limiting step in the incorporation of thymidine into the nucleotide pool as well as into DNA. The cells possess an excess of thymidine kinase, and thymidine is phosphorylated as rapidly as it enters the cells and is thereby trapped. At low concentrations, thymidine is taken up mainly by a transport reaction, whereas at concentrations above 2 microM simple diffusion becomes the principal mode of uptake. Evidence is presented that indicates that uridine and thymidine are transported by different systems. Upon inhibition of DNA synthesis, net thymidine incorporation into the acid-soluble pool ceased rapidly. Results from pulse-chase experiments indicate that a rapid turnover of dTTP to thymidine may be involved in limiting the level of thymine nucleotides in the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347249"}
{"pmid": "4347253", "title": "Modifications of lincomycin involving the carbohydrate portion. II. Analogues with D-gluco- and D-ido-stereochemistry.", "content": "Modifications of lincomycin involving the carbohydrate portion. II. Analogues with D-gluco- and D-ido-stereochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347253"}
{"pmid": "4347250", "title": "Cytochalasin B. VI. Competitive inhibition of nucleoside transport by cultured Novikoff rat hepatoma cells.", "content": "Cytochalasin B. VI. Competitive inhibition of nucleoside transport by cultured Novikoff rat hepatoma cells. Cytochalasin B competitively inhibits the transport of uridine and thymidine by Novikoff rat hepatoma cells growing in suspension culture with apparent K(i)'s of 2 and 6 microM, respectively, but has no effect on the intracellular phosphorylation of the nucleosides. Choline transport is not affected by cytochalasin B. Results from pulse-chase experiments indicate that cytochalasin B has no direct effect on the synthesis of RNA, DNA, or uridine diphosphate-sugars. The inhibition of uridine and thymidine incorporation into nucleic acids by cytochalasin B is solely the consequence of the inhibition of nucleoside transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347250"}
{"pmid": "4347251", "title": "The interaction of soluble horseradish peroxidase with mouse peritoneal macrophages in vitro.", "content": "The interaction of soluble horseradish peroxidase with mouse peritoneal macrophages in vitro. The in vitro interaction of soluble horseradish peroxidase (HRP) with homogeneous mono layers of mouse macrophages has been studied using sensitive biochemical and cytochemical techniques. The compartmentalization of HRP in extracellular and intracellular sites has been quantitatively evaluated. A significant fraction is bound to a serum-derived layer, which coats the surface of culture vessels and may be removed by appropriate washes. Macrophages interiorize HRP as a solute in pinocytic vesicles without appreciable binding of the glycoprotein to the plasma membrane. Uptake is directly proportional to the concentration of HRP in the culture medium. 1 x 10(6) cells ingest 0.0025% of the administered load per hr over a wide range of concentrations. Cytochemically, all demonstrable HRP is sequestered within the endocytic vesicles and secondary lysosomes of the vacuolar apparatus. After uptake, the enzymatic activity of HRP is inactivated exponentially with a half-life of 7-9 hr, until enzyme is no longer detectable. When macrophages have pinocytosed trace-labeled HRP-(125)I, cell-associated isotope disappears with a t (1/2) of 20-30 hr and they release monoiodotyrosine-(125)I into the culture medium. We were unable to obtain evidence that significant amounts of HRP (>2%) can be exocytosed after uptake, can exist intact on the cell surface, or can be digested extracellularly. It is difficult to reconcile these observations with several of the postulated mechanisms whereby macrophages are thought to play a prominent role in the induction of an immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347251"}
{"pmid": "4347252", "title": "Effect of adenosine 3'-5'-cyclic monophosphate on cell proliferation.", "content": "Effect of adenosine 3'-5'-cyclic monophosphate on cell proliferation. Secondary cultures of human diploid fibroblasts, which demonstrate density-dependent inhibition of cell growth, were used to study the effect of adenosine 3'-5'-cyclic monophosphate (cAMP) on cell proliferation. DNA synthesis in nonconfluent cultures and in contact-inhibited cultures stimulated to grow by refeeding with fresh medium was found to be inhibited by exogenous cAMP. The properties of this inhibition of DNA synthesis, together with the alterations in cAMP metabolism observed in confluent cultures of cells stimulated with fresh medium to resume growth, strongly suggest that cAMP is involved in contact-inhibition of cell proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347252"}
{"pmid": "4347255", "title": "Effect of catecholamine analogs on control of actomyosin by native tropomyosin and calcium: the nature of the negative inotropic receptor.", "content": "Effect of catecholamine analogs on control of actomyosin by native tropomyosin and calcium: the nature of the negative inotropic receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347255"}
{"pmid": "4347256", "title": "Studies of the presynaptic effect of  -bungarotoxin on neuromuscular transmission.", "content": "Studies of the presynaptic effect of  -bungarotoxin on neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347256"}
{"pmid": "4347257", "title": "Inhibition of adrenergic neurotransmission by parasympathomimetics in the rabbit ear artery.", "content": "Inhibition of adrenergic neurotransmission by parasympathomimetics in the rabbit ear artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347257"}
{"pmid": "4347258", "title": "Vasoconstriction produced by hallucinogens on isolated human and sheep umbilical vasculature.", "content": "Vasoconstriction produced by hallucinogens on isolated human and sheep umbilical vasculature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347258"}
{"pmid": "4347260", "title": "-Foetoprotein in rats with hepatomas induced by aflatoxin B 1 .", "content": "-Foetoprotein in rats with hepatomas induced by aflatoxin B 1 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347260"}
{"pmid": "4347261", "title": "Suppression of pituitary-adrenal response to stress with physiological plasma levels of corticosterone in the female rat.", "content": "Suppression of pituitary-adrenal response to stress with physiological plasma levels of corticosterone in the female rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347261"}
{"pmid": "4347263", "title": "Eczema herpeticum and pregnancy.", "content": "Eczema herpeticum and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347263"}
{"pmid": "4347264", "title": "Clear cell adenocarcinoma in young women.", "content": "Clear cell adenocarcinoma in young women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347264"}
{"pmid": "4347266", "title": "Respiratory responses to ACTH and dexamethasone in unanesthetized goats.", "content": "Respiratory responses to ACTH and dexamethasone in unanesthetized goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347266"}
{"pmid": "4347272", "title": "Proinsulin.", "content": "Proinsulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347272"}
{"pmid": "4347271", "title": "Possible implications for medicine of RNA-directed DNA synthesis.", "content": "Possible implications for medicine of RNA-directed DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347271"}
{"pmid": "4347273", "title": "Nuclear magnetic resonance studies of the dynamic aspects of molecular structure and interaction in biological systems.", "content": "Nuclear magnetic resonance studies of the dynamic aspects of molecular structure and interaction in biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347273"}
{"pmid": "4347281", "title": "On the development of amino acid transport systems.", "content": "On the development of amino acid transport systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347281"}
{"pmid": "4347285", "title": "Elicitation of periods of inhibition in human muscle by stimulation of cutaneous nerves.", "content": "Elicitation of periods of inhibition in human muscle by stimulation of cutaneous nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347285"}
{"pmid": "4347286", "title": "En bloc resection of the shoulder girdle: technique and indications. Report of a case.", "content": "En bloc resection of the shoulder girdle: technique and indications. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347286"}
{"pmid": "4347287", "title": "Scaphoid and lunate dislocation. Report of a case in a patient with peripheral neuropathy.", "content": "Scaphoid and lunate dislocation. Report of a case in a patient with peripheral neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347287"}
{"pmid": "4347288", "title": "An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses.", "content": "An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses. Chick, hamster, mouse, and rat embryo fibroblast cultures, transformed by either DNA or RNA viruses, show fibrinolytic activity under suitable conditions of growth and in appropriate media; normal counterpart cultures do not. The fibrinolysin is produced by the interaction of two protein factors: one of these, a cell factor, is released by transformed cells and accumulates in the medium when cultures are incubated in the absence of scrum. The second factor, the serum factor, is a specific protein that is present in sera of many avian and mammalian species, including man. Not all sera yield fibrinolysin on interaction with any given transformed cell factor, and the spectrum of activating sera is distinctive for each cell factor. This pattern appears to be determined by the cell type, rather than by the transforming virus. An important role for the fibrinolysin in oncogenic transformation is suggested by the following correlations. (a) The initial appearance of fibrinolysin precedes the morphological change after the transfer to permissive temperatures of chick fibroblast cultures infected with a temperature-sensitive mutant of RSV. (b) The initiation of fibrinolysis and of morphological change both require the synthesis of new protein, but not the synthesis of either DNA or rRNA. (c) The activity of the fibrinolysin is correlated with the retention of abnormal morphology in hamster cells transformed by SV-40. (d) The sera of normal chicks effectively activate fibrinolysis with the cell factor from transformed chick cells. In contrast the sera of chicks with RSV tumors do not; these contain an inhibitor of the fibrinolytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347288"}
{"pmid": "4347284", "title": "A pharmacological analysis of the response of dog anterior mesenteric vein to transmural electrical stimulation.", "content": "A pharmacological analysis of the response of dog anterior mesenteric vein to transmural electrical stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347284"}
{"pmid": "4347289", "title": "Epstein-Barr virus. Heterophile responses in squirrel monkeys inoculated with virus-transformed autologous leukocytes.", "content": "Epstein-Barr virus. Heterophile responses in squirrel monkeys inoculated with virus-transformed autologous leukocytes. Epstein-Barr virus (EBV)-transformed autologous lymphoblasts were repeatedly inoculated into three squirrel monkeys. Each animal developed the heterophile antibodies of infectious mononucleosis and EBV-specific antibodies. After serologic responses had disappeared or markedly declined, the animals were challenged with either whole cells, cell filtrate, or cell ghosts. Animals challenged with living cells and cell ghosts developed agglutinin responses; the recipient of filtrate did not. The results suggest that EBV induces the appearance of the infectious mononucleosis heterophile antigen on the transformed cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347289"}
{"pmid": "4347290", "title": "An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses.", "content": "An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses. Chick embryo fibroblast cultures develop fibrinolytic activity after transformation by Rous sarcoma virus (RSV). This fibrinolytic activity is not present in normal cultures, and it does not appear after infection with either nontransforming strains of avian leukosis viruses or cytocidal RNA and DNA viruses. In cultures infected with a temperature sensitive mutant of RSV the onset of fibrinolysis appears after exposure to permissive temperatures and precedes by a short interval the appearance of morphological evidence of transformation. See PDF for Structure The rate of fibrinolysis in transformed cultures depends on the nature of the serum that is present in the growth medium: some sera (e.g., monkey or chicken serum) promote high enzymatic activity, while others (calf, fetal bovine) do not. Some sera contain inhibitors of the fibrinolysin. Based on the effect of a small number of known inhibitors, at least one step of the fibrinolytic process shows specificity resembling that of trypsin. The sera of sarcoma-bearing chickens contain an inhibitor of the fibrinolysin, whereas normal chicken sera do not. For general discussion, conclusions, and summary see the accompanying paper, part II, (J. Exp. Med. 137:112).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347290"}
{"pmid": "4347291", "title": "Hormonal changes in ewes and their fetuses at parturition.", "content": "Hormonal changes in ewes and their fetuses at parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347291"}
{"pmid": "4347292", "title": "Small-angle x-ray scattering of human serum high-density lipoproteins.", "content": "Small-angle x-ray scattering of human serum high-density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347292"}
{"pmid": "4347297", "title": "Effect of folic acid on plasma renin activity in rats.", "content": "Effect of folic acid on plasma renin activity in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347297"}
{"pmid": "4347296", "title": "Treatment of myasthenia gravis.", "content": "Treatment of myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347296"}
{"pmid": "4347298", "title": "Unsuspected tuberculosis in a cancer patient.", "content": "Unsuspected tuberculosis in a cancer patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347298"}
{"pmid": "4347299", "title": "Pseudohypohyper what?", "content": "Pseudohypohyper what?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347299"}
{"pmid": "4347300", "title": "The clinical utility of brainscanning in nuclear medicine.", "content": "The clinical utility of brainscanning in nuclear medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347300"}
{"pmid": "4347301", "title": "Prostaglandin (PGA1), angiotensin and renal function.", "content": "Prostaglandin (PGA1), angiotensin and renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347301"}
{"pmid": "4347303", "title": "Studies in familial (medullary) thyroid carcinoma.", "content": "Studies in familial (medullary) thyroid carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347303"}
{"pmid": "4347306", "title": "Tektite II: medical supervision of the scientists in the sea. XIV. Biochemical, hematological, and endocrine studies.", "content": "Tektite II: medical supervision of the scientists in the sea. XIV. Biochemical, hematological, and endocrine studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347306"}
{"pmid": "4347307", "title": "Diagnostic problems in adenoviral disease.", "content": "Diagnostic problems in adenoviral disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347307"}
{"pmid": "4347308", "title": "Clinical appraisal of an inactivated bovine rhinotracheitis/parainfluenza-3 vaccine with pasteurella bacterin.", "content": "Clinical appraisal of an inactivated bovine rhinotracheitis/parainfluenza-3 vaccine with pasteurella bacterin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347308"}
{"pmid": "4347311", "title": "Functional regulation of mammalian ribonucleotide reductase.", "content": "Functional regulation of mammalian ribonucleotide reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347311"}
{"pmid": "4347312", "title": "New aspects of polyamine biosynthesis in eukaryotic organisms.", "content": "New aspects of polyamine biosynthesis in eukaryotic organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347312"}
{"pmid": "4347314", "title": "Mode of action of specific inactivating enzymes for pyridoxal enzymes and NAD-dependent enzymes and their biological significance.", "content": "Mode of action of specific inactivating enzymes for pyridoxal enzymes and NAD-dependent enzymes and their biological significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347314"}
{"pmid": "4347313", "title": "Two carbamyl phosphate synthetases of mammals: specific roles in control of pyrimidine and urea biosynthesis.", "content": "Two carbamyl phosphate synthetases of mammals: specific roles in control of pyrimidine and urea biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347313"}
{"pmid": "4347315", "title": "Regulatory characteristics of lactate dehydrogenases.", "content": "Regulatory characteristics of lactate dehydrogenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347315"}
{"pmid": "4347316", "title": "Isozyme studies on adult, regenerating, precancerous and developing liver in relation to findings in hepatomas.", "content": "Isozyme studies on adult, regenerating, precancerous and developing liver in relation to findings in hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347316"}
{"pmid": "4347317", "title": "Correlations between clinical and laboratory findings in virus infection of the female genital tract.", "content": "Correlations between clinical and laboratory findings in virus infection of the female genital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347317"}
{"pmid": "4347319", "title": "Skin test for amebiasis: an appraisal.", "content": "Skin test for amebiasis: an appraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347319"}
{"pmid": "4347318", "title": "Intrauterine electroencephalogram of the sheep fetus.", "content": "Intrauterine electroencephalogram of the sheep fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347318"}
{"pmid": "4347321", "title": "Guillain-Barré syndrome. Increased lymphoproliferative potential.", "content": "Guillain-Barré syndrome. Increased lymphoproliferative potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347321"}
{"pmid": "4347322", "title": "Chronic herpes simplex virus infection. Initiation in hamsters upon implantation of infected nonpermissive glial cells.", "content": "Chronic herpes simplex virus infection. Initiation in hamsters upon implantation of infected nonpermissive glial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347322"}
{"pmid": "4347323", "title": "The central nervous system in Fabry's disease. An ultrastructural study.", "content": "The central nervous system in Fabry's disease. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347323"}
{"pmid": "4347325", "title": "Scanning electron microscopic study of skeletal muscle. Normal, destrophic, and neurogenic atrophic muscle in mice and humans.", "content": "Scanning electron microscopic study of skeletal muscle. Normal, destrophic, and neurogenic atrophic muscle in mice and humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347325"}
{"pmid": "4347324", "title": "Myotonia induced by monocarboxylic aromatic acids. A possible mechanism.", "content": "Myotonia induced by monocarboxylic aromatic acids. A possible mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347324"}
{"pmid": "4347326", "title": "Prolonged paralysis in pseudocholinesterase deficiency.", "content": "Prolonged paralysis in pseudocholinesterase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347326"}
{"pmid": "4347327", "title": "Polymyositis with intranuclear inclusions. A light and electron microscopic study.", "content": "Polymyositis with intranuclear inclusions. A light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347327"}
{"pmid": "4347328", "title": "Metabolism of I-hydroxy-2-ketoheptadecane in myelinating brain.", "content": "Metabolism of I-hydroxy-2-ketoheptadecane in myelinating brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347328"}
{"pmid": "4347329", "title": "Incorporation of 2-deoxy-D-glucose into glycolipids of normal and SV40-transformed hamster cells.", "content": "Incorporation of 2-deoxy-D-glucose into glycolipids of normal and SV40-transformed hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347329"}
{"pmid": "4347330", "title": "Strain L fibroblast lipases. Purification and properties.", "content": "Strain L fibroblast lipases. Purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347330"}
{"pmid": "4347331", "title": "Growth of establishes lymphocytes in selective media: application to studies of inborn metabolic errors and somatic mutations.", "content": "Growth of establishes lymphocytes in selective media: application to studies of inborn metabolic errors and somatic mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347331"}
{"pmid": "4347332", "title": "The role of Epstein-Barr virus in establishing long-term human lymphocyte cultures.", "content": "The role of Epstein-Barr virus in establishing long-term human lymphocyte cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347332"}
{"pmid": "4347334", "title": "Methodology for cultured human lymphoid cells.", "content": "Methodology for cultured human lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347334"}
{"pmid": "4347333", "title": "Biohazards of long-term lymphocyte cultures.", "content": "Biohazards of long-term lymphocyte cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347333"}
{"pmid": "4347335", "title": "Spontaneous and induced transformation of human leukocytes in vitro.", "content": "Spontaneous and induced transformation of human leukocytes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347335"}
{"pmid": "4347336", "title": "The lymphocyte in culture: historic perspective.", "content": "The lymphocyte in culture: historic perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347336"}
{"pmid": "4347337", "title": "Herpesvirus hominis infection in patients with myeloproliferative and lymphoproliferative disorders.", "content": "Herpesvirus hominis infection in patients with myeloproliferative and lymphoproliferative disorders. Infection with Herpesvirus hominis, often associated with oral ulceration, was found to be more frequent in patients with myeloproliferative and lymphoproliferative disorders than in normal populations or patients with other diseases. This increased frequency was not associated with any deficiency of the humoral antibody response, suggesting a possible impairment of cell-mediated immunity. The otherwise untreatable oral lesions appeared to respond effectively to local irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347337"}
{"pmid": "4347338", "title": "Transient cranial mononeuropathy.", "content": "Transient cranial mononeuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347338"}
{"pmid": "4347340", "title": "Terminal oxidations in Bacillus brevis. Soluble reduced nicotinamide adenine dinucleotide oxidase activity in Bacillus brevis.", "content": "Terminal oxidations in Bacillus brevis. Soluble reduced nicotinamide adenine dinucleotide oxidase activity in Bacillus brevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347340"}
{"pmid": "4347339", "title": "Effects of postovulatory estrogen on progesterone and prostaglandin F levels in the monkey.", "content": "Effects of postovulatory estrogen on progesterone and prostaglandin F levels in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347339"}
{"pmid": "4347341", "title": "Multiplication of Mycobacterium lepraemurium in cell-free medium containing  -ketoglutaric acid and cytochrome c.", "content": "Multiplication of Mycobacterium lepraemurium in cell-free medium containing  -ketoglutaric acid and cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347341"}
{"pmid": "4347343", "title": "Conidiophore and spore development in Aspergillus nidulans.", "content": "Conidiophore and spore development in Aspergillus nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347343"}
{"pmid": "4347342", "title": "The levels of cyclic AMP during substrate-accelerated death.", "content": "The levels of cyclic AMP during substrate-accelerated death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347342"}
{"pmid": "4347346", "title": "Nurses as multiple therapists.", "content": "Nurses as multiple therapists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347346"}
{"pmid": "4347348", "title": "Teaching nurses to care for the dying patient.", "content": "Teaching nurses to care for the dying patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347348"}
{"pmid": "4347351", "title": "Megavitamins: pro and con.", "content": "Megavitamins: pro and con.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347351"}
{"pmid": "4347347", "title": "The nurse-therapist: a staff nurse position which emphasizes clinical practice.", "content": "The nurse-therapist: a staff nurse position which emphasizes clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347347"}
{"pmid": "4347360", "title": "Effects of vitamin E on toxicoderma associated with liver damage. Case report.", "content": "Effects of vitamin E on toxicoderma associated with liver damage. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347360"}
{"pmid": "4347352", "title": "The American Association of Retired Persons.", "content": "The American Association of Retired Persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347352"}
{"pmid": "4347350", "title": "Leadership and social change in 1973?", "content": "Leadership and social change in 1973?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347350"}
{"pmid": "4347353", "title": "Phasing out a state mental hospital.", "content": "Phasing out a state mental hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347353"}
{"pmid": "4347349", "title": "The role of the nurse in crisis intervention and suicide prevention.", "content": "The role of the nurse in crisis intervention and suicide prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347349"}
{"pmid": "4347363", "title": "Viewing the past as prologue for changes today and tomorrow.", "content": "Viewing the past as prologue for changes today and tomorrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347363"}
{"pmid": "4347364", "title": "Studies on the site of renal salt loss in a patient with Bartter's syndrome.", "content": "Studies on the site of renal salt loss in a patient with Bartter's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347364"}
{"pmid": "4347354", "title": "Gerontological nursing: where the action is.", "content": "Gerontological nursing: where the action is.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347354"}
{"pmid": "4347365", "title": "Thiamine deficiency in adult hospital patients.", "content": "Thiamine deficiency in adult hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347365"}
{"pmid": "4347372", "title": "Models of copper-protein interaction: the crystal structure of (glycyl-L-histidylglycinato)-copper (II) sodium perchlorate hydrate.", "content": "Models of copper-protein interaction: the crystal structure of (glycyl-L-histidylglycinato)-copper (II) sodium perchlorate hydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347372"}
{"pmid": "4347375", "title": "Histochemistry of hydroxysteroid dehydrogenases in the testis, adrenocartical tissue, and corpuscles of Stannius of Pseudopleuronectes americanus.", "content": "Histochemistry of hydroxysteroid dehydrogenases in the testis, adrenocartical tissue, and corpuscles of Stannius of Pseudopleuronectes americanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347375"}
{"pmid": "4347379", "title": "Journal's culpa?", "content": "Journal's culpa?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347379"}
{"pmid": "4347378", "title": "Reciprocal inhibitary effect of 5-iodo-2'-deoxyuridine and thymidine into the cells infected with herpes simplex virus.", "content": "Reciprocal inhibitary effect of 5-iodo-2'-deoxyuridine and thymidine into the cells infected with herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347378"}
{"pmid": "4347382", "title": "Phenelzine, mood response, and sleep.", "content": "Phenelzine, mood response, and sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347382"}
{"pmid": "4347383", "title": "Cholinergic activation of vestibular neurones leading to rapid eye movements in the mesencephalic cat.", "content": "Cholinergic activation of vestibular neurones leading to rapid eye movements in the mesencephalic cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347383"}
{"pmid": "4347384", "title": "Sphingolipids of mushrooms.", "content": "Sphingolipids of mushrooms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347384"}
{"pmid": "4347385", "title": "Temperature-dependent binding of estrogen receptor to chromatin.", "content": "Temperature-dependent binding of estrogen receptor to chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347385"}
{"pmid": "4347386", "title": "Affinity labeling of Escherichia coli B deoxyribonucleic acid dependent ribonucleic acid polymerase.", "content": "Affinity labeling of Escherichia coli B deoxyribonucleic acid dependent ribonucleic acid polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347386"}
{"pmid": "4347387", "title": "A random sequential mechanism for arginyl transfer ribonucleic acid synthetase of Escherichia coli.", "content": "A random sequential mechanism for arginyl transfer ribonucleic acid synthetase of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347387"}
{"pmid": "4347389", "title": "Control of lipid metabolism in hepatomas: conversion of glutamate carbon to fatty acid carbon via citrate in several transplantable hepatomas.", "content": "Control of lipid metabolism in hepatomas: conversion of glutamate carbon to fatty acid carbon via citrate in several transplantable hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347389"}
{"pmid": "4347391", "title": "A facile synthesis of 1-acyl ethylene glycol-2-phosphorylcholines.", "content": "A facile synthesis of 1-acyl ethylene glycol-2-phosphorylcholines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347391"}
{"pmid": "4347390", "title": "Glycerophosphoryl diglucosyl diglyceride, a new phosphoglycolipid from Streptococci.", "content": "Glycerophosphoryl diglucosyl diglyceride, a new phosphoglycolipid from Streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347390"}
{"pmid": "4347393", "title": "Role of high density lipoproteins in the lecithin-cholesterol acyltransferase activity with sonicated lecithin-cholesterol dispersions as substrate.", "content": "Role of high density lipoproteins in the lecithin-cholesterol acyltransferase activity with sonicated lecithin-cholesterol dispersions as substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347393"}
{"pmid": "4347392", "title": "The kinetic properties of very low density lipoprotein triglyceride in type 3 hyperlipoproteinemia.", "content": "The kinetic properties of very low density lipoprotein triglyceride in type 3 hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347392"}
{"pmid": "4347395", "title": "Molecular forms of enzymes in cancer.", "content": "Molecular forms of enzymes in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347395"}
{"pmid": "4347397", "title": "Glycogen storage diseases.", "content": "Glycogen storage diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347397"}
{"pmid": "4347399", "title": "The use of premarin, conjugated estrogens-equine to control. Functional uterine bleeding and the urinary estrogen metabolism after administration.", "content": "The use of premarin, conjugated estrogens-equine to control. Functional uterine bleeding and the urinary estrogen metabolism after administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347399"}
{"pmid": "4347401", "title": "Levels of cytochromes in heart, liver, kidney and brain in the developing rat.", "content": "Levels of cytochromes in heart, liver, kidney and brain in the developing rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347401"}
{"pmid": "4347402", "title": "Hyperpolarization by cyclic AMP (activation of diphosphoinositide kinase).", "content": "Hyperpolarization by cyclic AMP (activation of diphosphoinositide kinase).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347402"}
{"pmid": "4347403", "title": "Induction of brain tumours in high yield by administration of N-ethyl-N-nitrosourea to newborn rats.", "content": "Induction of brain tumours in high yield by administration of N-ethyl-N-nitrosourea to newborn rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347403"}
{"pmid": "4347404", "title": "Effect of N 6 O 2 -dibutyryl cyclic 3',5'-adenosine monophosphate on the pinocytosis of brain capillaries of mice.", "content": "Effect of N 6 O 2 -dibutyryl cyclic 3',5'-adenosine monophosphate on the pinocytosis of brain capillaries of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347404"}
{"pmid": "4347405", "title": "Interferon production by Sendai virus-treated hamster and monkey cells.", "content": "Interferon production by Sendai virus-treated hamster and monkey cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347405"}
{"pmid": "4347407", "title": "Biological properties of synthetic Ser 4 -Arg 8 -oxytocin (Ile 3 -Ser 4 -arginine vasopressin): role of the residue No. 4 in the hormone-pressor receptor interaction.", "content": "Biological properties of synthetic Ser 4 -Arg 8 -oxytocin (Ile 3 -Ser 4 -arginine vasopressin): role of the residue No. 4 in the hormone-pressor receptor interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347407"}
{"pmid": "4347406", "title": "Compensatory growth of the ovaries, adrenal glands and kidneys in blinded, anosmic rats.", "content": "Compensatory growth of the ovaries, adrenal glands and kidneys in blinded, anosmic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347406"}
{"pmid": "4347408", "title": "Plasma NADase in tuberculosis.", "content": "Plasma NADase in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347408"}
{"pmid": "4347409", "title": "Correlation between changes in antitumor immune parameters and tumor growth in vivo in rats.", "content": "Correlation between changes in antitumor immune parameters and tumor growth in vivo in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347409"}
{"pmid": "4347410", "title": "An analysis of dishabituation and sensitization of the gill-withdrawal reflex in Aplysia.", "content": "An analysis of dishabituation and sensitization of the gill-withdrawal reflex in Aplysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347410"}
{"pmid": "4347411", "title": "Recurrent excitation in the CA3 region of cat hippocampus.", "content": "Recurrent excitation in the CA3 region of cat hippocampus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347411"}
{"pmid": "4347412", "title": "Diurnal rhythms of sleep in the rat: augmentation of paradoxical sleep following alterations of the feeding schedule.", "content": "Diurnal rhythms of sleep in the rat: augmentation of paradoxical sleep following alterations of the feeding schedule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347412"}
{"pmid": "4347413", "title": "Synthesis of a fully protected heptacosapeptide norleucine analog corresponding to positions 21-47 of the primary structure of staphylococcal nuclease.", "content": "Synthesis of a fully protected heptacosapeptide norleucine analog corresponding to positions 21-47 of the primary structure of staphylococcal nuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347413"}
{"pmid": "4347414", "title": "Studies on the coordination of reduced glutathione to B 12  coenzymes.", "content": "Studies on the coordination of reduced glutathione to B 12  coenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347414"}
{"pmid": "4347415", "title": "Common peroneal nerve palsy. Evaluation and management.", "content": "Common peroneal nerve palsy. Evaluation and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347415"}
{"pmid": "4347417", "title": "Medical beliefs and practices of the Aymara indians.", "content": "Medical beliefs and practices of the Aymara indians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347417"}
{"pmid": "4347416", "title": "LSD and cyanotic congenital heart disease.", "content": "LSD and cyanotic congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347416"}
{"pmid": "4347418", "title": "The treatment of toxoplasmosis during pregnancy.", "content": "The treatment of toxoplasmosis during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347418"}
{"pmid": "4347419", "title": "Pseudo-fi + I-like sex factors, R62(I), selective for increased pilus synthesis.", "content": "Pseudo-fi + I-like sex factors, R62(I), selective for increased pilus synthesis. An I-like R factor, R62(I), inhibits F-like pilus synthesis and selects for mutant sex factors with a greatly increased capacity for pilus production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347419"}
{"pmid": "4347420", "title": "Differential block at high frequency of branches of a single axon innervating two muscles.", "content": "Differential block at high frequency of branches of a single axon innervating two muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347420"}
{"pmid": "4347421", "title": "An electron spin resonance study of nitrosamine anion radicals.", "content": "An electron spin resonance study of nitrosamine anion radicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347421"}
{"pmid": "4347422", "title": "Transformation of rat liver cells with chicken sarcoma virus B77 and murine sarcoma virus.", "content": "Transformation of rat liver cells with chicken sarcoma virus B77 and murine sarcoma virus. Rat liver cells in vitro were transformed with chicken sarcoma virus B77, giving RL(B77) cells, and with murine sarcoma virus (Harvey), giving RL(MSV) cells. Rat liver cells transformed spontaneously in vitro were designated RL cells. In addition, the RL(MSV) cell line was adapted for growth in culture fluid containing 25 mug of 5-bromodeoxyuridine per ml. All cell lines were tumorigenic in 1-wk-old rats. The number of cells needed for induction of tumor growth was 1,000-fold higher in the case of RL(B77) cells in comparison with RL(MSV) cells and RL cells. No production of viral particles from any of the cell lines investigated was detected by plating concentrated supernatant fluid of the cultures on different secondary embryo cells with and without fusion by Sendai virus, by labeling with uridine-5-(3)H, or by assay for deoxyribonucleic acid polymerase activity. The viral genome was rescued by fusion of RL(B77) cells with chicken cells. Chicken sarcoma virus rescued from (RL(B77) cells differed in plating efficiency on duck cells from B77 virus rescued from transformed rat embryo cells. No virus was rescued after fusion of RL(MSV) and RL cells with mouse, rat, or chicken embryo cells. Infectious murine sarcoma virus can be induced by 5-bromodeoxyuridine from RL(MSV) cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347422"}
{"pmid": "4347423", "title": "Stimulation of aryl hydrocarbon hydroxylase induction in cell cultures by interferon.", "content": "Stimulation of aryl hydrocarbon hydroxylase induction in cell cultures by interferon. In cell cultures previously treated with homologous interferon, the magnitude of antiviral activity and the degree of stimulation of aryl hydrocarbon hydroxylase induction appear to be directly related. In a highly purified mouse interferon preparation, the factor stimulating hydroxylase induction and the factor directing antiviral activity are inactivated by heating to 70 C or by treating with trypsin. Also, both activities demonstrate species specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347423"}
{"pmid": "4347424", "title": "Extraordinary effects of specific monovalent cations on activation of reovirus transcriptase by chymotrypsin in vitro.", "content": "Extraordinary effects of specific monovalent cations on activation of reovirus transcriptase by chymotrypsin in vitro. Activation of reovirus transcriptase activity, latent in intact virions, by digestion of purified virions with chymotrypsin (CHT) in vitro shows a stringent requirement for specific monovalent cations. Cs(+), Rb(+), or K(+) ions are capable of facilitating activation by chymotryptic digestion. Na(+), Li(+), or NH(4) (+) ions are not capable of facilitating the CHT activation of polymerase activity and are antagonistic towards the effects of the facilitating ions. The data indicate that the effect of the cations is exerted on activation of the polymerase activity by CHT as opposed to an effect on polymerization per se. This effect may be important biologically in that it provides a mechanism whereby the virion can sense whether it is in an intracellular or an extracellular environment and thereby can avoid premature uncoating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347424"}
{"pmid": "4347426", "title": "Effect of viral double-stranded RNA on protein synthesis in intact cells.", "content": "Effect of viral double-stranded RNA on protein synthesis in intact cells. The addition of purified, noninfectious, double-stranded RNA of bovine enterovirus, a picornavirus, to intact cells in culture results in a rapid cessation of cellular polypeptide synthesis. This inhibition is specific for host cell protein synthesis since the translation of picornavirus-specific proteins is not affected by the double-stranded viral RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347426"}
{"pmid": "4347425", "title": "Characterization of morphologic revertants of murine and avian sarcoma virus-transformed cells.", "content": "Characterization of morphologic revertants of murine and avian sarcoma virus-transformed cells. Morphologic revertants which contain avian or murine sarcoma viruses have previously been isolated at low frequency from clonal lines of transformed mammalian cells. In the present study, these lines have been further characterized. They are indistinguishable from nontransformed parent cell lines with respect to parameters such as saturation density and colony formation in depleted medium or on monolayers of contact-inhibited cells. The rate of glucose uptake had also reverted to normal. The malignant potential of one of the revertant lines was examined and found to be markedly reduced compared to that of the corresponding transformed cells. The differences in the susceptibilities of revertant cells to retransformation by the same or other oncogenic viruses suggest that different cellular genes may be involved in expression of transformation by various tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347425"}
{"pmid": "4347427", "title": "Stimulation of Sendai virion transcriptase by polyanions.", "content": "Stimulation of Sendai virion transcriptase by polyanions. Exogenous polyribonucleotides stimulated the ribonucleic acid (RNA) transcriptase in Sendai virions. Added yeast RNA, polyadenylic acid, or polycytidylic acid increased incorporation of (3)H-guanosine monophosphate as much as fivefold. The products of stimulated reactions were virus-specific as determined by hybridization with Sendai virion RNA, but they sedimented more slowly (13s) than the product of an unstimulated reaction (16s). The stimulating activity was nondialyzable and heat stable, but was abolished by alkaline hydrolysis. Nucleoside monophosphates, individually or in combination, were ineffective, confirming the requirement for a polymer. Among other substances tested for effects on Sendai virion transcriptase, polyaspartic acid and polyglutamic acid stimulated the enzyme; polyinosinic acid, polyuridylic acid, and polyamines had no effect; and dextran sulfate and polyvinyl sulfate were inhibitory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347427"}
{"pmid": "4347429", "title": "Isolation of an infectious ribonucleoprotein from vesicular stomatitis virus containing an active RNA transcriptase.", "content": "Isolation of an infectious ribonucleoprotein from vesicular stomatitis virus containing an active RNA transcriptase. A ribonucleoprotein complex (TNP) containing an active RNA polymerase was isolated from purified vesicular stomatitis virus particles. The TNP sedimented through a sucrose gradient as a single band and appeared under the electron microscope as discrete long filaments in a spiral configuration. TNP contained one major and two minor polypeptides, but not the polypeptides associated with the outer coat of vesicular stomatitis virus. BHK-21 clone 13 cells could be infected with TNP, yielding infectious virus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347429"}
{"pmid": "4347430", "title": "In vivo conversion of the single-stranded DNA of the kilham rat virus to a double-stranded form.", "content": "In vivo conversion of the single-stranded DNA of the kilham rat virus to a double-stranded form. Kilham rat virus (KRV) contains linear, single-stranded DNA in the virion. The fate of radioactive viral DNA was followed after infection of monolayer cells. Within 60 min after infection of cells, 28 to 42% of the parental viral DNA is converted to a new form. This new DNA form is believed to be double stranded and linear on the basis of its sedimentation in neutral and alkaline sucrose gradients, elution from hydroxyapatite columns, its buoyant density in equilibrium CsCl density gradients, and appearance in the electron microscope. The double-stranded linear KRV DNA may be analogous to the replicative form of certain bacteriophages, including phiX174, which contain single-stranded circular genomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347430"}
{"pmid": "4347428", "title": "Chromatographic and electrophoretic analysis of viral proteins from hamster and chicken cells transformed by Rous sarcoma virus.", "content": "Chromatographic and electrophoretic analysis of viral proteins from hamster and chicken cells transformed by Rous sarcoma virus. Several methods have been explored for the detection and characterization of viral proteins from soluble extracts of cells transformed by Rous sarcoma virus (RSV). Viral antigens have been analyzed after gel filtration in several solvents. In addition, immune complexes formed with virus-specific sera have been isolated by agarose gel filtration and by high- or low-speed centrifugation through sucrose solutions. Radioactive proteins from these immune complexes have been analyzed by gel filtration in 6 m guanidine hydrochloride or by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. Comparison with proteins from purified virus indicates the presence of two viral core proteins (gs1 and gs2) in the soluble fraction from virus-producing chicken cells. In the same fraction from RSV-transformed hamster cells (which do not produce virus), three gs proteins (gs1, gs2, and gs3) could be identified. The soluble viral gs proteins are strongly bound to at least two larger polypeptides in cell extracts. These polypeptides do not appear to be viral in origin and have the property of undergoing a time-dependent aggregation in the extracts. One of these cell-derived proteins, which is present in a variety of uninfected cell types, closely resembles actin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347428"}
{"pmid": "4347432", "title": "Picornaviral gene order: comparison of a rhinovirus with a cardiovirus.", "content": "Picornaviral gene order: comparison of a rhinovirus with a cardiovirus. We describe conditions for unmasking virus-specific protein synthesis in cells infected with rhinoviruses 1A and 2. The gene order and cleavage pattern of rhinovirus 1A show many similarities to those of encephalomyocarditis virus and of poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347432"}
{"pmid": "4347431", "title": "Role of mitochondria in the production of RNA-containing tumor viruses.", "content": "Role of mitochondria in the production of RNA-containing tumor viruses. The role of mitochondria in the reproduction of RNA-containing tumor viruses was examined by using ethidium bromide (EB) to induce degenerative effects in mitochondria. The effects of EB in murine and avian cells were monitored by electron microscopy. Chronically infected mouse (JLS-V5) cells, in which extensive mitochondrial changes were induced, continued to produce murine leukemia virus. Also, complete reproductive cycles of Rous sarcoma virus (RSV) occurred in newly infected chicken embryo cells exposed to EB. Morphological transformation characteristic of infection of chicken embryo cells by RSV occurred in cells which contained induced aberrant mitochondria. The results demonstrate that mitochondria play a relatively minor role, if any, in the reproduction of RNA-containing tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347431"}
{"pmid": "4347434", "title": "A note on the duration of neutralizing antibody against avian encephalomyelitis virus in chickens.", "content": "A note on the duration of neutralizing antibody against avian encephalomyelitis virus in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347434"}
{"pmid": "4347435", "title": "The fine structure of Marek's disease virus and herpesvirus of turkey in cell culture.", "content": "The fine structure of Marek's disease virus and herpesvirus of turkey in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347435"}
{"pmid": "4347436", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 15-1973.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 15-1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347436"}
{"pmid": "4347438", "title": "The possibilities of applying mass miniature radiography for public health care.", "content": "The possibilities of applying mass miniature radiography for public health care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347438"}
{"pmid": "4347439", "title": "The role of mass chest radiography in preventive medicine.", "content": "The role of mass chest radiography in preventive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347439"}
{"pmid": "4347440", "title": "Conservative mediastinal node dissection for the treatment of carcinoma of the breast.", "content": "Conservative mediastinal node dissection for the treatment of carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347440"}
{"pmid": "4347441", "title": "Experiences with bilateral primary carcinoma of the breast.", "content": "Experiences with bilateral primary carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347441"}
{"pmid": "4347443", "title": "Effect of chlorothiazide and sodium on vascular responsiveness to angiotensin II.", "content": "Effect of chlorothiazide and sodium on vascular responsiveness to angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347443"}
{"pmid": "4347444", "title": "Changes in renin kinetics induced by nephrectomy.", "content": "Changes in renin kinetics induced by nephrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347444"}
{"pmid": "4347445", "title": "Effects of ganglionic blocking agents on adrenergic transmission in rat mesenteric arteries.", "content": "Effects of ganglionic blocking agents on adrenergic transmission in rat mesenteric arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347445"}
{"pmid": "4347446", "title": "Hydration changes produced by central infusion of angiotensin II.", "content": "Hydration changes produced by central infusion of angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347446"}
{"pmid": "4347447", "title": "Metabolic clearance rate of radioiodinated angiotensin II in normal men.", "content": "Metabolic clearance rate of radioiodinated angiotensin II in normal men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347447"}
{"pmid": "4347448", "title": "Enterostomal therapy: better care for the ostomy patient.", "content": "Enterostomal therapy: better care for the ostomy patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347448"}
{"pmid": "4347451", "title": "Biochemical and morphological aspects of zinc deficiency in Rhodotorula gracilis.", "content": "Biochemical and morphological aspects of zinc deficiency in Rhodotorula gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347451"}
{"pmid": "4347452", "title": "Enzyme induction and repression in Arthrobacter crystallopoietes.", "content": "Enzyme induction and repression in Arthrobacter crystallopoietes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347452"}
{"pmid": "4347454", "title": "Regulation of the synthesis of mitochondrial enzymes and cytochromes. Distinction between catabolite repression and anaerobiosis in Saccharomyces cerevisiae.", "content": "Regulation of the synthesis of mitochondrial enzymes and cytochromes. Distinction between catabolite repression and anaerobiosis in Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347454"}
{"pmid": "4347453", "title": "Chemical composition of gas vesicles isolated from Anabaena flos-aquae.", "content": "Chemical composition of gas vesicles isolated from Anabaena flos-aquae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347453"}
{"pmid": "4347455", "title": "Impression-expression reactions in cellular pathology.", "content": "Impression-expression reactions in cellular pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347455"}
{"pmid": "4347456", "title": "Cobaltous ion complex of reduced lipoamide dehydrogenase.", "content": "Cobaltous ion complex of reduced lipoamide dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347456"}
{"pmid": "4347458", "title": "Glycoproteins associated with nuclei of cells before and after transformation by a ribonucleic acid virus.", "content": "Glycoproteins associated with nuclei of cells before and after transformation by a ribonucleic acid virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347458"}
{"pmid": "4347457", "title": "On the active site topography of isoleucyl transfer ribonucleic acid synthetase of Escherichia coli B.", "content": "On the active site topography of isoleucyl transfer ribonucleic acid synthetase of Escherichia coli B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347457"}
{"pmid": "4347459", "title": "Amino acid incorporation and products of protein synthesis in isolated chloroplasts of Euglena gracilis.", "content": "Amino acid incorporation and products of protein synthesis in isolated chloroplasts of Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347459"}
{"pmid": "4347462", "title": "Hormonal effects on thymidine kinase and thymidylate kinase activity of estrogen-dependent tumors in the rat.", "content": "Hormonal effects on thymidine kinase and thymidylate kinase activity of estrogen-dependent tumors in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347462"}
{"pmid": "4347463", "title": "Ultrastructural effects of 5-bromodeoxyuridine and 5-fluorouracil in Drosophila.", "content": "Ultrastructural effects of 5-bromodeoxyuridine and 5-fluorouracil in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347463"}
{"pmid": "4347464", "title": "Activities and isoenzyme patterns of some enzymes of glucose metabolism in human primary malignant hepatoma.", "content": "Activities and isoenzyme patterns of some enzymes of glucose metabolism in human primary malignant hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347464"}
{"pmid": "4347465", "title": "The carcinogenic potential of aflatoxin or its metabolites in rats from dams fed aflatoxin pre- and postpartum.", "content": "The carcinogenic potential of aflatoxin or its metabolites in rats from dams fed aflatoxin pre- and postpartum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347465"}
{"pmid": "4347466", "title": "Ultrastructural, histological, and biochemical alterations produced by 12-O-tetradecanoyl-phorbol-13-acetate on mouse epidermis and their relevance to skin tumor promotion.", "content": "Ultrastructural, histological, and biochemical alterations produced by 12-O-tetradecanoyl-phorbol-13-acetate on mouse epidermis and their relevance to skin tumor promotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347466"}
{"pmid": "4347467", "title": "Inhibition of transfer and ribosomal RNA methylases by polyinosinate.", "content": "Inhibition of transfer and ribosomal RNA methylases by polyinosinate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347467"}
{"pmid": "4347468", "title": "Transplantability and biological behavior of mouse liver tumors induced by ethylnitrosourea.", "content": "Transplantability and biological behavior of mouse liver tumors induced by ethylnitrosourea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347468"}
{"pmid": "4347469", "title": "Cyclic adenosine 3',5'-monophosphate phosphodiesterase activity in normal, differentiating, regenerating, and neoplastic liver.", "content": "Cyclic adenosine 3',5'-monophosphate phosphodiesterase activity in normal, differentiating, regenerating, and neoplastic liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347469"}
{"pmid": "4347470", "title": "Reversible and irreversible effects of tissue culture on enzyme patterns of spontaneous mouse tumors and mouse and human embryo tissues.", "content": "Reversible and irreversible effects of tissue culture on enzyme patterns of spontaneous mouse tumors and mouse and human embryo tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347470"}
{"pmid": "4347471", "title": "Dihydroorotate dehydrogenase in liver and Morris hepatomas.", "content": "Dihydroorotate dehydrogenase in liver and Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347471"}
{"pmid": "4347473", "title": "Enhanced responses to tyramine and angiotensin produced by 4,4'-biphenylene bis-((2-oxoethylene)-bis-(2,2-diethoxylethyl)dimethylammonium bromide) (DMAE).", "content": "Enhanced responses to tyramine and angiotensin produced by 4,4'-biphenylene bis-((2-oxoethylene)-bis-(2,2-diethoxylethyl)dimethylammonium bromide) (DMAE).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347473"}
{"pmid": "4347475", "title": "Selective release of newly synthesized cardiac norepinephrine induced by angiotensin II.", "content": "Selective release of newly synthesized cardiac norepinephrine induced by angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347475"}
{"pmid": "4347474", "title": "Angiotensin-induced contraction of the cat nictitating membrane.", "content": "Angiotensin-induced contraction of the cat nictitating membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347474"}
{"pmid": "4347476", "title": "The effect of a hemicholinium analogue, HC-15, of neuromuscular transmission.", "content": "The effect of a hemicholinium analogue, HC-15, of neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347476"}
{"pmid": "4347477", "title": "Cellular analysis of immunosuppression to synthetic polypeptide immunogens induced by a murine leukemia virus.", "content": "Cellular analysis of immunosuppression to synthetic polypeptide immunogens induced by a murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347477"}
{"pmid": "4347478", "title": "The physicochemical characteristics and purification of slow-reacting substance of anaphylaxis.", "content": "The physicochemical characteristics and purification of slow-reacting substance of anaphylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347478"}
{"pmid": "4347479", "title": "Variations in complement levels during active and adoptive immunization.", "content": "Variations in complement levels during active and adoptive immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347479"}
{"pmid": "4347480", "title": "Inactivation of human interferon by urine.", "content": "Inactivation of human interferon by urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347480"}
{"pmid": "4347487", "title": "Twice weekly tuberculosis chemotherapy.", "content": "Twice weekly tuberculosis chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347487"}
{"pmid": "4347488", "title": "Synaptic delay and time course of postsynaptic potentials at the junction between hair cells and eighth nerve fibers in the goldfish.", "content": "Synaptic delay and time course of postsynaptic potentials at the junction between hair cells and eighth nerve fibers in the goldfish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347488"}
{"pmid": "4347489", "title": "Neonatal sepsis due to clostridium perfringens.", "content": "Neonatal sepsis due to clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347489"}
{"pmid": "4347490", "title": "The hyperlipoproteinemias. Detection, diagnosis, and management.", "content": "The hyperlipoproteinemias. Detection, diagnosis, and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347490"}
{"pmid": "4347491", "title": "Granular cell tumours of the larynx.", "content": "Granular cell tumours of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347491"}
{"pmid": "4347492", "title": "SV40 virus transformation of mouse 3T3 cells does not specifically enhance sugar transport.", "content": "SV40 virus transformation of mouse 3T3 cells does not specifically enhance sugar transport. The apparent enhancement of 2-deoxy-D-glucose uptake by mouse 3T3 cells accompanying transformation by SV40 virus is not due primarily to an effect on the transport process but to enhanced phosphorylation of the sugar by intracellular kinases. Moreover, the effect is not specifically a function of the presence of the viral genome, but is a reflection of the overall growth rate and physiological state of the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347492"}
{"pmid": "4347501", "title": "Urethroplasty for anterior urethral stricture.", "content": "Urethroplasty for anterior urethral stricture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347501"}
{"pmid": "4347502", "title": "The syndrome of hypertension, hyperreninemia and secondary aldosteronism associated with renal juxtaglomerular cell tumor (primary reninism).", "content": "The syndrome of hypertension, hyperreninemia and secondary aldosteronism associated with renal juxtaglomerular cell tumor (primary reninism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347502"}
{"pmid": "4347503", "title": "The cancer associated antigen test as an index to failure of complete removal of urological cancers.", "content": "The cancer associated antigen test as an index to failure of complete removal of urological cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347503"}
{"pmid": "4347506", "title": "Plan and operation of the health and nutrition examination survey. United states--1971-1973.", "content": "Plan and operation of the health and nutrition examination survey. United states--1971-1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347506"}
{"pmid": "4347508", "title": "Increasing antibody titers to herpes simplex virus type 2 during follow-up of women with cervical dysplasia.", "content": "Increasing antibody titers to herpes simplex virus type 2 during follow-up of women with cervical dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347508"}
{"pmid": "4347509", "title": "Prevalence of antibodies to Epstein-Barr virus, cytomegalovirus and Toxoplasma in a Mexican highland community.", "content": "Prevalence of antibodies to Epstein-Barr virus, cytomegalovirus and Toxoplasma in a Mexican highland community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347509"}
{"pmid": "4347510", "title": "Incidence and etiology of pneumonia, croup and bronchiolitis in preschool children belonging to a prepaid medical care group over a four-year period.", "content": "Incidence and etiology of pneumonia, croup and bronchiolitis in preschool children belonging to a prepaid medical care group over a four-year period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347510"}
{"pmid": "4347511", "title": "Viral and mycoplasmal pneumonia in a prepaid medical care group during an eight-year period.", "content": "Viral and mycoplasmal pneumonia in a prepaid medical care group during an eight-year period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347511"}
{"pmid": "4347512", "title": "Protamine kinase independent of adenosine 3',5'-monophosphate from rat brain cytosol.", "content": "Protamine kinase independent of adenosine 3',5'-monophosphate from rat brain cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347512"}
{"pmid": "4347513", "title": "Cyclic AMP and citric acid accumulation by Aspergillus niger.", "content": "Cyclic AMP and citric acid accumulation by Aspergillus niger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347513"}
{"pmid": "4347514", "title": "RNase and alkali sensitivity of closed circular mitochondrial DNA of rat ascites hepatoma cells.", "content": "RNase and alkali sensitivity of closed circular mitochondrial DNA of rat ascites hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347514"}
{"pmid": "4347516", "title": "Comparative binding of albumin and  -glucuronidase by rat liver microsomes.", "content": "Comparative binding of albumin and  -glucuronidase by rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347516"}
{"pmid": "4347515", "title": "Carbon tetrachloride activation in liver microsomes from rats induced with 3-methylcholantrene.", "content": "Carbon tetrachloride activation in liver microsomes from rats induced with 3-methylcholantrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347515"}
{"pmid": "4347517", "title": "The terminal oxidases of Azotobacter vinelandii.", "content": "The terminal oxidases of Azotobacter vinelandii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347517"}
{"pmid": "4347518", "title": "Differences in the carbon tetrachloride-induced damage to components of the smooth and rough endoplasmic reticulum from rat liver.", "content": "Differences in the carbon tetrachloride-induced damage to components of the smooth and rough endoplasmic reticulum from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347518"}
{"pmid": "4347519", "title": "The role of cyclic AMP in the phosphorylation of proteins in human erythrocyte membranes.", "content": "The role of cyclic AMP in the phosphorylation of proteins in human erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347519"}
{"pmid": "4347520", "title": "UDP-glucose pyrophosphorylase synthesis in myxamoebae of Dictyostelium discoideum.", "content": "UDP-glucose pyrophosphorylase synthesis in myxamoebae of Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347520"}
{"pmid": "4347521", "title": "Studies of the Rous sarcoma virus RNA: characterization of the 5'-terminus.", "content": "Studies of the Rous sarcoma virus RNA: characterization of the 5'-terminus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347521"}
{"pmid": "4347523", "title": "UDP-glucose dehydrogenase: substrate binding stoichiometry and affinity.", "content": "UDP-glucose dehydrogenase: substrate binding stoichiometry and affinity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347523"}
{"pmid": "4347522", "title": "4,4'-Bis dimethylaminodiphenylcarbinol: a new reagent for selective chemical modification. Interaction with porcine malate dehydrogenase.", "content": "4,4'-Bis dimethylaminodiphenylcarbinol: a new reagent for selective chemical modification. Interaction with porcine malate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347522"}
{"pmid": "4347524", "title": "The effect of inhibitors of RNA and protein synthesis on dibutyryl cyclic AMP mediated morphological transformations of Chinese hamster ovary cells in vitro.", "content": "The effect of inhibitors of RNA and protein synthesis on dibutyryl cyclic AMP mediated morphological transformations of Chinese hamster ovary cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347524"}
{"pmid": "4347525", "title": "EPR behavior of a soluble cardiac NADH dehydrogenase.", "content": "EPR behavior of a soluble cardiac NADH dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347525"}
{"pmid": "4347526", "title": "The primary acid product of DPNH.", "content": "The primary acid product of DPNH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347526"}
{"pmid": "4347527", "title": "Modification of hamster sperm adenyl cyclase by capacitation in vitro.", "content": "Modification of hamster sperm adenyl cyclase by capacitation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347527"}
{"pmid": "4347528", "title": "Role of  -NADH for microsomal ethanol oxidation.", "content": "Role of  -NADH for microsomal ethanol oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347528"}
{"pmid": "4347529", "title": "Release and binding of proteins and enzymes with isolated inner mitochondrial membranes.", "content": "Release and binding of proteins and enzymes with isolated inner mitochondrial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347529"}
{"pmid": "4347530", "title": "The kinetics of the cytochrome-c-azurin redox equilibrium.", "content": "The kinetics of the cytochrome-c-azurin redox equilibrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347530"}
{"pmid": "4347532", "title": "Charge distribution in electron transport components: cytochrome c and cytochrome c oxidase mixtures.", "content": "Charge distribution in electron transport components: cytochrome c and cytochrome c oxidase mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347532"}
{"pmid": "4347531", "title": "Activation of glycogen synthetase and inactivation of phosphorylase kinase by the same phosphoprotein phosphatase.", "content": "Activation of glycogen synthetase and inactivation of phosphorylase kinase by the same phosphoprotein phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347531"}
{"pmid": "4347533", "title": "Acetylcholine stimulates hydrolysis of  32 P-labeled phosphatidic acid in guinea pig synaptosomes.", "content": "Acetylcholine stimulates hydrolysis of  32 P-labeled phosphatidic acid in guinea pig synaptosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347533"}
{"pmid": "4347534", "title": "New poliovirus-related polypeptides in the nucleus-associated fraction of HeLa cell cytoplasm.", "content": "New poliovirus-related polypeptides in the nucleus-associated fraction of HeLa cell cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347534"}
{"pmid": "4347536", "title": "Biosynthesis of the parasporal inclusion of Bacillus thuringiensis: half-life of its corresponding messenger RNA.", "content": "Biosynthesis of the parasporal inclusion of Bacillus thuringiensis: half-life of its corresponding messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347536"}
{"pmid": "4347537", "title": "Oestradiol \"neo nuclear receptor\" in the rat uterus: sedimentation constant and conditions of formation.", "content": "Oestradiol \"neo nuclear receptor\" in the rat uterus: sedimentation constant and conditions of formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347537"}
{"pmid": "4347541", "title": "Central pleomorphic adenoma in the mandible: report of a case.", "content": "Central pleomorphic adenoma in the mandible: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347541"}
{"pmid": "4347543", "title": "Method for determination of cyclic AMP in plasma.", "content": "Method for determination of cyclic AMP in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347543"}
{"pmid": "4347544", "title": "Stable reagents for determination of serum triglycerides by a colorimetric Hantzsch condensation method.", "content": "Stable reagents for determination of serum triglycerides by a colorimetric Hantzsch condensation method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347544"}
{"pmid": "4347545", "title": "Specificity of leucine stimulation of insulin release.", "content": "Specificity of leucine stimulation of insulin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347545"}
{"pmid": "4347546", "title": "Effects of eserine and neostigmine on release of acetylcholine into perfused cerebral ventricles of unanaesthetized dogs.", "content": "Effects of eserine and neostigmine on release of acetylcholine into perfused cerebral ventricles of unanaesthetized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347546"}
{"pmid": "4347547", "title": "Effect of parainfluenza-3 neuraminidase on bovine nasal secretion.", "content": "Effect of parainfluenza-3 neuraminidase on bovine nasal secretion. Three samples of bovine nasal secretion were each separated into a sol phase and a surface gel phase. In all samples, the gel phase contained an approximately four times greater amount of bound N-acetylneuraminic acid (NANA) than the sol phase. From the gel phase, bound NANA could be released by exposure to parainfluenza-3 virus neuraminidase. The surface gel appears to be a natural substrate for this enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347547"}
{"pmid": "4347548", "title": "Semisynthetic  -lactam antibiotics. 1. Acylation of 6-aminopenicillanic acid with activated derivatives of  -sulfophenylacetic acid.", "content": "Semisynthetic  -lactam antibiotics. 1. Acylation of 6-aminopenicillanic acid with activated derivatives of  -sulfophenylacetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347548"}
{"pmid": "4347549", "title": "Antimetabolites of coenzyme Q. 17. Improved synthesis of 5-hydroxy-1,4-benzoquinone analogs and their indices.", "content": "Antimetabolites of coenzyme Q. 17. Improved synthesis of 5-hydroxy-1,4-benzoquinone analogs and their indices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347549"}
{"pmid": "4347550", "title": "Design, synthesis, and broad spectrum antiviral activity of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide and related nucleosides.", "content": "Design, synthesis, and broad spectrum antiviral activity of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide and related nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347550"}
{"pmid": "4347551", "title": "Potential antitumor agents. 6. Possible irreversible inhibitors of ribonucleoside diphosphate reductase.", "content": "Potential antitumor agents. 6. Possible irreversible inhibitors of ribonucleoside diphosphate reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347551"}
{"pmid": "4347552", "title": "Potential antifertility agents. 2. Tetrazole derivatives of nonsteroidal estrogens.", "content": "Potential antifertility agents. 2. Tetrazole derivatives of nonsteroidal estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347552"}
{"pmid": "4347553", "title": "Interplay of vasodilator and vasoconstrictor substances in the femoral arterial bed: identification of the angiotensin cofactor.", "content": "Interplay of vasodilator and vasoconstrictor substances in the femoral arterial bed: identification of the angiotensin cofactor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347553"}
{"pmid": "4347555", "title": "Alterations of rat liver lysosomes and smooth endoplasmic reticulum induced by the diazafluoranthen derivative AC-3579. I. Morphologic and biochemical lesions.", "content": "Alterations of rat liver lysosomes and smooth endoplasmic reticulum induced by the diazafluoranthen derivative AC-3579. I. Morphologic and biochemical lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347555"}
{"pmid": "4347554", "title": "Effect of AY-9944, a cholesterol biosynthesis inhibitor, on fetal lung development and on the development of type II alveolar epithelial cells.", "content": "Effect of AY-9944, a cholesterol biosynthesis inhibitor, on fetal lung development and on the development of type II alveolar epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347554"}
{"pmid": "4347558", "title": "What's your diagnosis? Adenocystic carcinoma.", "content": "What's your diagnosis? Adenocystic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347558"}
{"pmid": "4347561", "title": "Amnesia, consolidation, and retrieval.", "content": "Amnesia, consolidation, and retrieval.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347561"}
{"pmid": "4347566", "title": "Metabolism of glucose in the human endometrium with special reference to fertility and contraception.", "content": "Metabolism of glucose in the human endometrium with special reference to fertility and contraception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347566"}
{"pmid": "4347565", "title": "Purine overproduction in man associated with increased phosphoribosylpyrophosphate synthetase activity.", "content": "Purine overproduction in man associated with increased phosphoribosylpyrophosphate synthetase activity. In hemolyzates from red cells of two brothers with purine overproduction and gout, activity of phosphoribosylpyrophosphate synthetase is more than twofold greater than that measured in normal or other gouty individuals. The increased enzyme activity, which is also demonstrable in fibroblasts of the one patient tested, is associated with increased production of 5-phosphoribosyl-1-pyrophosphate by intact cells, an indication that the enzyme abnormality is the basis for the purine overproduction. This genetic abnormality is an example of an increased enzyme activity producing a disease state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347565"}
{"pmid": "4347567", "title": "Fibrin degradation products during postoperative radiotherapy of ovarian carcinoma.", "content": "Fibrin degradation products during postoperative radiotherapy of ovarian carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347567"}
{"pmid": "4347568", "title": "The number of glomerular cells and substructures in early juvenile diabetes. A quantitative electron microscopic study.", "content": "The number of glomerular cells and substructures in early juvenile diabetes. A quantitative electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347568"}
{"pmid": "4347569", "title": "Metastases to the uterus. Five cases diagnosed on the basis of curettings.", "content": "Metastases to the uterus. Five cases diagnosed on the basis of curettings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347569"}
{"pmid": "4347570", "title": "Sexual precocity attributable to ectopic gonadotropin secretion by hepatoblastoma.", "content": "Sexual precocity attributable to ectopic gonadotropin secretion by hepatoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347570"}
{"pmid": "4347571", "title": "The possible role of the carotid bodies as chemoreceptors in the laryngeal reflex.", "content": "The possible role of the carotid bodies as chemoreceptors in the laryngeal reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347571"}
{"pmid": "4347578", "title": "On a collagenase-like enzyme detected in the extracts of hypothalamus and hypophysis.", "content": "On a collagenase-like enzyme detected in the extracts of hypothalamus and hypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347578"}
{"pmid": "4347579", "title": "Composition of low density lipoprotein in children with familial hyperbetalipoproteinaemia and the effect of treatment.", "content": "Composition of low density lipoprotein in children with familial hyperbetalipoproteinaemia and the effect of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347579"}
{"pmid": "4347580", "title": "A reproducible quantitative collagenase radiofibril assay.", "content": "A reproducible quantitative collagenase radiofibril assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347580"}
{"pmid": "4347581", "title": "Electroimmunodiffusion of   2 M, IgA and IgM in nanogram quantities with a hydroxyethylcellulose-agarose gel: application to unconcentrated CSF.", "content": "Electroimmunodiffusion of   2 M, IgA and IgM in nanogram quantities with a hydroxyethylcellulose-agarose gel: application to unconcentrated CSF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347581"}
{"pmid": "4347582", "title": "Regulatory processes in the maturation and early cleavage of amphibian eggs.", "content": "Regulatory processes in the maturation and early cleavage of amphibian eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347582"}
{"pmid": "4347583", "title": "Studies on the human glomerular basement membrane. Composition, nature of the carbohydrate units and chemical changes in diabetes mellitus.", "content": "Studies on the human glomerular basement membrane. Composition, nature of the carbohydrate units and chemical changes in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347583"}
{"pmid": "4347588", "title": "Sensitivity of the electron spin resonance technique as applied in histochemical research on normal and pathological calcified tissues.", "content": "Sensitivity of the electron spin resonance technique as applied in histochemical research on normal and pathological calcified tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347588"}
{"pmid": "4347589", "title": "Dynamics of axial ligation in metalloporphyrins. II.  Porphyrin \"inversion\" and halogen exchange in high-spin iron complexes.", "content": "Dynamics of axial ligation in metalloporphyrins. II.  Porphyrin \"inversion\" and halogen exchange in high-spin iron complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347589"}
{"pmid": "4347590", "title": "Electron spin resonance of (25 Mg)chlorophyll a.", "content": "Electron spin resonance of (25 Mg)chlorophyll a.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347590"}
{"pmid": "4347591", "title": "The future for medical education and women in medicine.", "content": "The future for medical education and women in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347591"}
{"pmid": "4347584", "title": "Pitfalls in the diagnosis of amebic colitis.", "content": "Pitfalls in the diagnosis of amebic colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347584"}
{"pmid": "4347592", "title": "Rehabilitation medicine as an art form.", "content": "Rehabilitation medicine as an art form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347592"}
{"pmid": "4347593", "title": "Medical education. One step at a time.", "content": "Medical education. One step at a time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347593"}
{"pmid": "4347594", "title": "The radiologic aspects of toxoplasmosis.", "content": "The radiologic aspects of toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347594"}
{"pmid": "4347585", "title": "Paget's disease of the anus secondary to a malignant papillary adenoma of the rectum.", "content": "Paget's disease of the anus secondary to a malignant papillary adenoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347585"}
{"pmid": "4347595", "title": "Radioimmunoassay of mammalian type C viral proteins. 3. Detection of viral antigen in normal murine cells and tissues.", "content": "Radioimmunoassay of mammalian type C viral proteins. 3. Detection of viral antigen in normal murine cells and tissues. A radioimmunoassay specific for a murine leukemia virus structural protein, the gs antigen, detects an antigenic reactivity in normal murine cells in culture and natural tissues. The assay was shown to measure an antigen that is highly related to the virion protein as shown by absorption tests, immunoadsorbent chromatography, and by analysis of linearized dose-response curves. These findings combined with the finding of viral-specific RNA indicate that portions of the viral genome are being expressed with a much greater frequency than previously appreciated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347595"}
{"pmid": "4347596", "title": "Prevention of cell-to-cell spread of herpes simplex virus by leukocytes.", "content": "Prevention of cell-to-cell spread of herpes simplex virus by leukocytes. Antibody to herpes simplex virus (HSV) plus complement destroyed HSV-infected cells but did not stop the spread of the infection. Studies on the relationship between the time of appearance of viral antigens on the cell surface, immunological destruction of the cells by antiviral antibody and complement, and transfer of the virus to adjacent cells showed that the virus spread from infected to uninfected cells before the infected cells were susceptible to immunological destruction. Incubation of infected monolayers with leukocytes, however, stopped the spread of the virus by nonspecifically damaging both infected and uninfected cells and by presumably breaking intercellular bridges. When leukocytes were removed from infected monolayers, viral plaques developed. If, however, antiviral antibody and complement were added to monolayers before the leukocytes were removed, the development of plaques was prevented. These findings suggest that both antibody and leukocytes are needed to cure HSV infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347596"}
{"pmid": "4347597", "title": "Immunologic rejection of diethylnitrosamine-induced hepatomas in strain 2 guinea pigs: participation of basophilic leukocytes and macrophage aggregates.", "content": "Immunologic rejection of diethylnitrosamine-induced hepatomas in strain 2 guinea pigs: participation of basophilic leukocytes and macrophage aggregates. The morphologic events associated with the immunologic rejection by strain 2 guinea pigs of ascites variants of two lines of diethylnitrosamine-induced tumors have been studied by light and electron microscopy. Tumor injection sites in the skin of control animals exhibited clusters of viable, actively mitotic tumor cells along with a modest inflammatory infiltrate composed of lymphocytes, macrophages, neutrophils, and rare basophils. In contrast, similar injections of either tumor line in specifically sensitized guinea pigs elicited typical delayed-type skin reactions associated with tumor cell necrosis and a more extensive inflammatory infiltrate including a selective increase in the number of basophilic leukocytes (12%, line 1, or 23%, line 10, of total inflammatory cells). That basophils may have a role in tumor resistance in vivo is suggested by the close anatomic associations observed between basophils and tumor cells, and by the fact that basophils were the only inflammatory cell to demonstrate a relative increase in frequency in the lesions of sensitized as compared with control animals. Moreover, intraperitoneal injection of line 1 tumor in specifically sensitized animals elicited a striking basophilia within 24 h. Unlike macrophages, basophils did not phagocytose tumor cells but did evidence occasional extrusion of granules and frequently exhibited loss of granule staining density, a change that may be related to release of mediator substances. Electron microscope studies of line 1 tumor rejection in the peritoneal cavities of specifically sensitized guinea pigs demonstrated aggregations of \"activated\" macrophages, lymphocytes, basophils, and damaged or dead tumor cells. These aggregates, held together by complex interdigitations of macrophage villi, closely resembled those occurring in vitro among peritoneal exudate cells whose migration from capillary tubes was inhibited by migration inhibition factor (MIF). Moreover, cells in these aggregates, as well as macrophages inhibited by MIF in vitro, lacked a normal coating of cell surface material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347597"}
{"pmid": "4347598", "title": "Accelerated hypertension secondary to oral contraceptives.", "content": "Accelerated hypertension secondary to oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347598"}
{"pmid": "4347604", "title": "Bone as a target organ: toward a better definition of osteoporosis.", "content": "Bone as a target organ: toward a better definition of osteoporosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347604"}
{"pmid": "4347605", "title": "Distribution of tritiated human chorionic gonadotropin in superovulated rat ovary.", "content": "Distribution of tritiated human chorionic gonadotropin in superovulated rat ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347605"}
{"pmid": "4347606", "title": "Cyclic 3',5'-AMP phosphodiesterase activity during cyclic AMP-induced differentiation of neuroblastoma cells in culture.", "content": "Cyclic 3',5'-AMP phosphodiesterase activity during cyclic AMP-induced differentiation of neuroblastoma cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347606"}
{"pmid": "4347607", "title": "Differentiation of a myocardial depressant factor present in shock plasma from known plasma peptides and salts.", "content": "Differentiation of a myocardial depressant factor present in shock plasma from known plasma peptides and salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347607"}
{"pmid": "4347608", "title": "Microheterogeneity of N-acetyl- -D-hexosaminidase of bull epididymis.", "content": "Microheterogeneity of N-acetyl- -D-hexosaminidase of bull epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347608"}
{"pmid": "4347610", "title": "Interaction of prostaglandin E 1  and angiotensin II on centrally mediated pressor activities in the cat.", "content": "Interaction of prostaglandin E 1  and angiotensin II on centrally mediated pressor activities in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347610"}
{"pmid": "4347609", "title": "Interferon induced by endotoxin and Newcastle disease virus in rabbit macrophage and kidney cell cultures.", "content": "Interferon induced by endotoxin and Newcastle disease virus in rabbit macrophage and kidney cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347609"}
{"pmid": "4347611", "title": "Biochemical events in murine cytomegalovirus-infected mouse liver.", "content": "Biochemical events in murine cytomegalovirus-infected mouse liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347611"}
{"pmid": "4347612", "title": "Renal medullary adenylate cyclase in drug-induced nephrogenic diabetes insipidus.", "content": "Renal medullary adenylate cyclase in drug-induced nephrogenic diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347612"}
{"pmid": "4347617", "title": "Alpha-ecdysone and 20-hydroxyecdysone from frass of the tobacco hornworm, Manduca sexta (L.).", "content": "Alpha-ecdysone and 20-hydroxyecdysone from frass of the tobacco hornworm, Manduca sexta (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347617"}
{"pmid": "4347618", "title": "Characterization of the metabolites of vitamin D 3  in the chick.", "content": "Characterization of the metabolites of vitamin D 3  in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347618"}
{"pmid": "4347620", "title": "Biochemistry of the hydroxyprolines.", "content": "Biochemistry of the hydroxyprolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347620"}
{"pmid": "4347621", "title": "Parainfluenza virus Sendai infection in macrophages, ependyma, choroid plexus, vascular endothelium and respiratory tract of mice.", "content": "Parainfluenza virus Sendai infection in macrophages, ependyma, choroid plexus, vascular endothelium and respiratory tract of mice. Immunofluorescent observations showed that after intranasal instillation of parainfluenza 1 (Sendai) virus into adult mice, infection is confined to the epithelial lining of the larger airways. Alveolar macrophages were not significantly involved, although they could be infected in vitro. In suckling mice, the infection was more acutely lethal and extended into the terminal air spaces. The intranasal susceptibility of adult mice was not reproducibly affected by treatment with potent antithymocyte serum, and there were no obvious pathogenic effects when heterologous antiserum was instilled intranasally into infected mice. Peritoneal macrophages were infected by intraperitoneally injected Sendai virus, with production of a highly viscous peritoneal exudate. Kupffer cells of the liver and endothelial cells in large veins and auricles were infected by intravenously injected virus. When injected intracerebrally, Sendai virus infected ependyma and choroid plexus epithelium. Adult mice often survived, in spite of ependymal destruction and changes in ventricular morphology. Astrocytes were activated but not infected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347621"}
{"pmid": "4347622", "title": "The Hermansky-Pudlak syndrome: ultrastructure of bone marrow macrophages.", "content": "The Hermansky-Pudlak syndrome: ultrastructure of bone marrow macrophages. The present investigation has explored the fine structure of the lipid inclusions which fill the bone marrow macrophages of patients with the Hermansky-Pudlak syndrome. Red blood cells are the major substrate of the reticular macrophages, and incomplete digestion of erythrocytes leads to formation of the massive inclusions. Progressive transformation of the macrophages results in an end-stage cell whose damaged cytoplasm is nearly replaced by huge lipid-containing vacuoles surrounded by particulate debris. This type of cell has not been found in bone marrows from patients with hemolytic, thrombocytopenic or lipid storage diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347622"}
{"pmid": "4347625", "title": "Action of quinacrine mustard on polynucleotides.", "content": "Action of quinacrine mustard on polynucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347625"}
{"pmid": "4347626", "title": "Studies in bioluminescence. VII. Bacterial NADH: flavin mononucleotide oxidoreductase.", "content": "Studies in bioluminescence. VII. Bacterial NADH: flavin mononucleotide oxidoreductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347626"}
{"pmid": "4347627", "title": "Inhibition by sulfonamides of the photoreductive step in spinach chloroplast photosynthesis.", "content": "Inhibition by sulfonamides of the photoreductive step in spinach chloroplast photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347627"}
{"pmid": "4347629", "title": "Familial recurrent polyneuropathy. A family and a survey.", "content": "Familial recurrent polyneuropathy. A family and a survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347629"}
{"pmid": "4347630", "title": "Aspects of subcortical organization of feeding revealed by hypothalamic disconnexions in Macaca mulatta.", "content": "Aspects of subcortical organization of feeding revealed by hypothalamic disconnexions in Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347630"}
{"pmid": "4347631", "title": "Proteolytic activity of a small variety of Entamoeba histolytica. II. Detection of enzyme and effect of pH on its activity.", "content": "Proteolytic activity of a small variety of Entamoeba histolytica. II. Detection of enzyme and effect of pH on its activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347631"}
{"pmid": "4347632", "title": "Cytomegalovirus syndrome post-renal transplantation. Treatment with cytosine arabinoside.", "content": "Cytomegalovirus syndrome post-renal transplantation. Treatment with cytosine arabinoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347632"}
{"pmid": "4347633", "title": "Thecoma in pregnancy.", "content": "Thecoma in pregnancy. A description is briefly given of a patient whose pregnancy was complicated by an ovarian thecoma which ruptured spontaneously.Eleven previously reported instances of the combination of thecoma and pregnancy are summarized.Although the present case appears to be the first in which the mother has survived rupture of the tumour, in view of the result to the child this can hardly be claimed as a triumph of obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347633"}
{"pmid": "4347636", "title": "Hypersomnia in manic-depressive disease (a preliminary report).", "content": "Hypersomnia in manic-depressive disease (a preliminary report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347636"}
{"pmid": "4347638", "title": "Clinical neuropathological conference.", "content": "Clinical neuropathological conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347638"}
{"pmid": "4347637", "title": "Mechanism of acupunctural anesthesia. The two-gate control theory.", "content": "Mechanism of acupunctural anesthesia. The two-gate control theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347637"}
{"pmid": "4347644", "title": "Separation of methylated bases of ribonucleic acid by two-dimensional thin-layer chromatography.", "content": "Separation of methylated bases of ribonucleic acid by two-dimensional thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347644"}
{"pmid": "4347646", "title": "Liquid chromatographic analysis of nucleosides, purine base-modified adenosine derivatives and 3',5'-cyclic AMP.", "content": "Liquid chromatographic analysis of nucleosides, purine base-modified adenosine derivatives and 3',5'-cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347646"}
{"pmid": "4347647", "title": "Increased mycoplasma-cell association in transformed human amnion cells.", "content": "Increased mycoplasma-cell association in transformed human amnion cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347647"}
{"pmid": "4347648", "title": "Failure of cytarabine in varicella-zoster infections.", "content": "Failure of cytarabine in varicella-zoster infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347648"}
{"pmid": "4347650", "title": "Treatment of labial herpes.", "content": "Treatment of labial herpes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347650"}
{"pmid": "4347649", "title": "Herpetic chancre.", "content": "Herpetic chancre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347649"}
{"pmid": "4347651", "title": "Metoposcopy and kindred arts.", "content": "Metoposcopy and kindred arts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347651"}
{"pmid": "4347653", "title": "The exotic animal problem.", "content": "The exotic animal problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347653"}
{"pmid": "4347658", "title": "Subcutaneous mastectomy for central tumors of the breast, with immediate reconstruction.", "content": "Subcutaneous mastectomy for central tumors of the breast, with immediate reconstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347658"}
{"pmid": "4347659", "title": "Disseminated cytomegalovirus infection associated with death in a patient with severe facial injuries. Case report.", "content": "Disseminated cytomegalovirus infection associated with death in a patient with severe facial injuries. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347659"}
{"pmid": "4347654", "title": "The ventromedial hypothalamus and aggressive behaviors.", "content": "The ventromedial hypothalamus and aggressive behaviors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347654"}
{"pmid": "4347664", "title": "Nutrition, metabolism, and blood lipids in humans with type II A  hyperlipoproteinemia.", "content": "Nutrition, metabolism, and blood lipids in humans with type II A  hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347664"}
{"pmid": "4347655", "title": "A comparison of the motivational properties of thirst induced by intracranial angiotensin and by water deprivation.", "content": "A comparison of the motivational properties of thirst induced by intracranial angiotensin and by water deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347655"}
{"pmid": "4347657", "title": "Depression of the H-reflex during tooth grinding in sleep.", "content": "Depression of the H-reflex during tooth grinding in sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347657"}
{"pmid": "4347665", "title": "The role of pancreatic enzymes in digestion.", "content": "The role of pancreatic enzymes in digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347665"}
{"pmid": "4347666", "title": "Calcium metabolism in pancreatic disease.", "content": "Calcium metabolism in pancreatic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347666"}
{"pmid": "4347667", "title": "Papio cynocephalus age determination.", "content": "Papio cynocephalus age determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347667"}
{"pmid": "4347656", "title": "Modulation of visual cortex inhibition during reticular evoked arousal.", "content": "Modulation of visual cortex inhibition during reticular evoked arousal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347656"}
{"pmid": "4347668", "title": "Noradrenergic control of circadian rhythms in Cebus albifrons.", "content": "Noradrenergic control of circadian rhythms in Cebus albifrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347668"}
{"pmid": "4347670", "title": "Tumors in nonhuman primates: observations during a six-year period in the Yerkes primate center colony.", "content": "Tumors in nonhuman primates: observations during a six-year period in the Yerkes primate center colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347670"}
{"pmid": "4347669", "title": "Lead poisoning in zoo-dwelling primates.", "content": "Lead poisoning in zoo-dwelling primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347669"}
{"pmid": "4347671", "title": "Herpesvirus simiae infection in Macaca radiata.", "content": "Herpesvirus simiae infection in Macaca radiata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347671"}
{"pmid": "4347672", "title": "Infectious diseases in primates--introduction and bibliography.", "content": "Infectious diseases in primates--introduction and bibliography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347672"}
{"pmid": "4347673", "title": "Infectious diseases of primates related to capture and transportation.", "content": "Infectious diseases of primates related to capture and transportation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347673"}
{"pmid": "4347674", "title": "The role of H 2 O 2  generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors.", "content": "The role of H 2 O 2  generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347674"}
{"pmid": "4347675", "title": "The essential role of the imidazole group of glucagon in its biological function.", "content": "The essential role of the imidazole group of glucagon in its biological function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347675"}
{"pmid": "4347676", "title": "The reaction between indole 3-acetic acid and horseradish peroxidase.", "content": "The reaction between indole 3-acetic acid and horseradish peroxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347676"}
{"pmid": "4347677", "title": "Pyridine nucleotide biosynthesis in Claviceps.", "content": "Pyridine nucleotide biosynthesis in Claviceps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347677"}
{"pmid": "4347678", "title": "Cytochrome c interaction with membranes. I. Use of a fluorescent chromophore in the study of cytochrome c interaction with artificial and mitochondrial membranes.", "content": "Cytochrome c interaction with membranes. I. Use of a fluorescent chromophore in the study of cytochrome c interaction with artificial and mitochondrial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347678"}
{"pmid": "4347679", "title": "Isolated adrenal cortex cells: ACTH agonists, partial agonists, antagonists; cyclic AMP and corticosterone production.", "content": "Isolated adrenal cortex cells: ACTH agonists, partial agonists, antagonists; cyclic AMP and corticosterone production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347679"}
{"pmid": "4347680", "title": "Adenylate cyclase from guinea pig lung: further characterization and inhibitory effects of substrate analogs and cyclic nucleotides.", "content": "Adenylate cyclase from guinea pig lung: further characterization and inhibitory effects of substrate analogs and cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347680"}
{"pmid": "4347681", "title": "Regulation of glycogen metabolism in the adrenal gland. IV. The effect of insulin on glycogen synthetase, phosphorylase, and related metabolites.", "content": "Regulation of glycogen metabolism in the adrenal gland. IV. The effect of insulin on glycogen synthetase, phosphorylase, and related metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347681"}
{"pmid": "4347683", "title": "Stimulation of the (Na +  + K + )-dependent adenosine triphosphatase by amino acids and phosphatidylserine: chelation of trace metal inhibitors.", "content": "Stimulation of the (Na +  + K + )-dependent adenosine triphosphatase by amino acids and phosphatidylserine: chelation of trace metal inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347683"}
{"pmid": "4347682", "title": "Some regulatory properties of glycogen phosphorylase from Streptococcus salivarius.", "content": "Some regulatory properties of glycogen phosphorylase from Streptococcus salivarius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347682"}
{"pmid": "4347685", "title": "Role of mitochondria in the sex-directed flocculation of a fission yeast.", "content": "Role of mitochondria in the sex-directed flocculation of a fission yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347685"}
{"pmid": "4347684", "title": "The effects of adenine nucleotides on NADH binding to mitochondrial malate dehydrogenase.", "content": "The effects of adenine nucleotides on NADH binding to mitochondrial malate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347684"}
{"pmid": "4347687", "title": "Proteins of the thermophilic fungus Humicola lanuginosa. II. Some physicochemical properties of a cytochrome c.", "content": "Proteins of the thermophilic fungus Humicola lanuginosa. II. Some physicochemical properties of a cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347687"}
{"pmid": "4347686", "title": "The effect of dibutyryl adenosine 3':5'-cyclic monophosphate on the synthesis of glycolipids by normal and transformed Nil cells.", "content": "The effect of dibutyryl adenosine 3':5'-cyclic monophosphate on the synthesis of glycolipids by normal and transformed Nil cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347686"}
{"pmid": "4347688", "title": "Initiation of protein synthesis in vivo in poliovirus-infected HeLa cells.", "content": "Initiation of protein synthesis in vivo in poliovirus-infected HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347688"}
{"pmid": "4347689", "title": "Substrate inhibition of soluble and bound lactate dehydrogenase (isoenzyme 5).", "content": "Substrate inhibition of soluble and bound lactate dehydrogenase (isoenzyme 5).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347689"}
{"pmid": "4347691", "title": "Phospholipase C purification and specificity with respect to individual phospholipids and brain microsomal membrane phospholipids.", "content": "Phospholipase C purification and specificity with respect to individual phospholipids and brain microsomal membrane phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347691"}
{"pmid": "4347690", "title": "Effects of nucleotides and Na +  on ouabain activation of the phosphatase associated with Na + , K + -ATPase.", "content": "Effects of nucleotides and Na +  on ouabain activation of the phosphatase associated with Na + , K + -ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347690"}
{"pmid": "4347692", "title": "Ro le of phospholipids in the NA + ,K + -stimulated adenosine triphosphatase system of brain microsomes.", "content": "Ro le of phospholipids in the NA + ,K + -stimulated adenosine triphosphatase system of brain microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347692"}
{"pmid": "4347693", "title": "Ultraviolet sensitivity of helper function of murine leukemia virus.", "content": "Ultraviolet sensitivity of helper function of murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347693"}
{"pmid": "4347695", "title": "Isolation of a herpesvirus from a pigeon.", "content": "Isolation of a herpesvirus from a pigeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347695"}
{"pmid": "4347694", "title": "The nature and treatment of skin conditions observed in horses in Queensland.", "content": "The nature and treatment of skin conditions observed in horses in Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347694"}
{"pmid": "4347696", "title": "Redox interactions between cytochrome components and transition ions and metals.", "content": "Redox interactions between cytochrome components and transition ions and metals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347696"}
{"pmid": "4347697", "title": "Zonal diffusion, a new technique. Application to the determination of the molecular weight of M13 viral deoxyribonucleic acid.", "content": "Zonal diffusion, a new technique. Application to the determination of the molecular weight of M13 viral deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347697"}
{"pmid": "4347698", "title": "Electron paramagnetic resonance studies on cobalamin-dependent ribonucleotide reduction.", "content": "Electron paramagnetic resonance studies on cobalamin-dependent ribonucleotide reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347698"}
{"pmid": "4347699", "title": "Separation of phospholipids from glucose-6-phosphatase by gel chromatography. Specificity of phospholipid reactivation.", "content": "Separation of phospholipids from glucose-6-phosphatase by gel chromatography. Specificity of phospholipid reactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347699"}
{"pmid": "4347701", "title": "Kinetics and equilibria in partially reduced flavine solutions.", "content": "Kinetics and equilibria in partially reduced flavine solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347701"}
{"pmid": "4347700", "title": "Guanine phosphoribosyltransferase from Escherichia coli, specificity and properties.", "content": "Guanine phosphoribosyltransferase from Escherichia coli, specificity and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347700"}
{"pmid": "4347702", "title": "States of hemoglobin in solution.", "content": "States of hemoglobin in solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347702"}
{"pmid": "4347703", "title": "Occurrence and properties of a chromatin-associated F1-histone phosphokinase in mitotic Chinese hamster cells.", "content": "Occurrence and properties of a chromatin-associated F1-histone phosphokinase in mitotic Chinese hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347703"}
{"pmid": "4347704", "title": "Direct incorporation of fatty acids into the halosulfatides of Ochromonas danica.", "content": "Direct incorporation of fatty acids into the halosulfatides of Ochromonas danica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347704"}
{"pmid": "4347705", "title": "Isolation and fractionation of yeast nucleic acids. I. Characterization of poly(L-lysine) kieselguhr chromatography using yeast nucleic acids.", "content": "Isolation and fractionation of yeast nucleic acids. I. Characterization of poly(L-lysine) kieselguhr chromatography using yeast nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347705"}
{"pmid": "4347706", "title": "Isolation and fractionation of yeast nucleic acids. II. Rapid isolation of mitochondrial deoxyribonucleic acid by poly(L-lysine) kieselguhr chromatography.", "content": "Isolation and fractionation of yeast nucleic acids. II. Rapid isolation of mitochondrial deoxyribonucleic acid by poly(L-lysine) kieselguhr chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347706"}
{"pmid": "4347707", "title": "Effects of catecholamines and adenosine derivatives given into the brain of fowls.", "content": "Effects of catecholamines and adenosine derivatives given into the brain of fowls. 1. Adult fowls (Gallus domesticus) with cannulae chronically implanted into the IIIrd cerebral ventricle and various other sites of the brain received microinfusions or injections of catecholamines, adenosine, 3',5'-cyclic AMP or its dibutyryl derivative. The effects of these substances on behaviour, electrocortical activity and body temperature were studied.2. Behavioural and electrocortical sleep with fall in body temperature were obtained with intraventricular noradrenaline, alpha-methylnoradrenaline and isoprenaline; dopamine was ineffective. The doses required to elicit sleep were smaller than those affecting body temperature. Following mebanazine, the effects of noradrenaline were prolonged and doses of dopamine, previously ineffective, lowered body temperature and induced behavioural and electrocortical sleep.3. Noradrenaline, alpha-methylnoradrenaline, isoprenaline and dopamine infused into the hypothalamus induced sleep and lowered body temperature. Effective doses of noradrenaline, alpha-methylnoradrenaline and isoprenaline infused into the hypothalamus were one-twentieth to one-fifth those for intraventricular injection. Tachypnoea developed with isoprenaline and dopamine. Additionally with dopamine, there was deviation of the head to the contralateral side, together with repetitive jerking movements of the head. These effects were prolonged and intensified by mebanazine, whereas the involuntary movements with dopamine were greatly reduced by haloperidol.4. Involuntary movements, but without sleep, were induced by infusing dopamine into the paleostriatum augmentatum; noradrenaline infused into this site was ineffective.5. In three of five fowls pretreated with aminophylline, 3',5'-cyclic AMP infused into the hypothalamus induced behavioural and electrocortical sleep; without aminophylline pretreatment, 3',5'-cyclic AMP was ineffective. Adenosine infused into the hypothalamus, following pretreatment of fowls with aminophylline, consistently induced behavioural and electrocortical sleep. Dibutyryl cyclic AMP infused into the hypothalamus of intact fowls elicited behavioural arousal, followed by bursts of electrocortical spikes (6 Hz) over both cerebral hemispheres, spikes subsequently becoming regular at 1 Hz. Clonic limb and body movements occasionally accompanied the bursts of spike activity, infrequently developing into convulsions. In fowl encéphale isolé preparations, in which dibutyryl cyclic AMP was infused into the hypothalamus, spike activity was confined to the ipsilateral hemisphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347707"}
{"pmid": "4347710", "title": "Effect of fast-growing transplantable hepatoma on cell proliferation in host tissue of the mouse.", "content": "Effect of fast-growing transplantable hepatoma on cell proliferation in host tissue of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347710"}
{"pmid": "4347708", "title": "Actions of the selective inhibitor of cholinesterase tetramonoisopropyl pyrophosphortetramide on the rat phrenic nerve-diaphragm preparation.", "content": "Actions of the selective inhibitor of cholinesterase tetramonoisopropyl pyrophosphortetramide on the rat phrenic nerve-diaphragm preparation. 1. Tetramonoisopropyl pyrophosphortetramide (iso-OMPA) added for 15 min to the rat isolated phrenic nerve-diaphragm in a concentration of 30 muM, produced a complete selective and stable inhibition of cholinesterase. A concentration of 3 muM produced near complete inhibition of cholinesterase, and a concentration of 300 muM also inhibited acetylcholinesterase marginally.2. Inhibition of cholinesterase was associated with a sustained increase in the neuromuscular blocking action of exogenous butyrylcholine but not of exogenous acetylcholine. Iso-OMPA, 300 muM, in addition caused transient increases in the sensitivity of the rat diaphragm to exogenous acetylcholine and butyrylcholine. In the same concentration, it had a curare-like action on the frog rectus abdominis muscle preparation.3. Iso-OMPA, 30 muM, caused reversible increases in the amplitude of the twitch response and tetanic responses, which were of a similar magnitude in the indirectly stimulated preparation and the directly stimulated curarized preparation. Caffeine had a similar effect on the twitch response and its effectiveness was increased by iso-OMPA, and vice-versa. Amongst anticholinesterases, octamethyl pyrophosphortetramide and tetraethylpyrophosphate also enhanced the amplitude of the tetanic response, but paraoxon, dyflos, and mipafox did not.4. It is concluded that iso-OMPA, in concentrations (3 and 30 muM) which in 15 min give near maximal or maximal selective inhibition of cholinesterase, has no effect on the transmission of nerve impulses at the neuromuscular junction, but enhances reversibly the amplitude of the contractile response to stimulation by a direct action upon the muscle fibre, which involves a mechanism related to but not identical with that by which caffeine potentiates twitch tension. In higher concentrations, iso-OMPA has a curare-like action at the neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347708"}
{"pmid": "4347711", "title": "Isozyme patterns of branched-chain amino acid transaminase in cultured rat hepatocytes.", "content": "Isozyme patterns of branched-chain amino acid transaminase in cultured rat hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347711"}
{"pmid": "4347712", "title": "Effect of p-hydroxyacetanilide on liver cancer induction by N hydroxy-N-2-fluorenylacetamide.", "content": "Effect of p-hydroxyacetanilide on liver cancer induction by N hydroxy-N-2-fluorenylacetamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347712"}
{"pmid": "4347713", "title": "Rapid uptake of dietary cholesterol by hyperplastic liver nodules and primary hepatomas.", "content": "Rapid uptake of dietary cholesterol by hyperplastic liver nodules and primary hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347713"}
{"pmid": "4347715", "title": "Tumor-specific transplantation antigens in reticulum cell sarcomas and lymphomas induced by the friend virus complex.", "content": "Tumor-specific transplantation antigens in reticulum cell sarcomas and lymphomas induced by the friend virus complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347715"}
{"pmid": "4347716", "title": "Estimation of the association constant of the estrogen-receptor complex in human breast cancer.", "content": "Estimation of the association constant of the estrogen-receptor complex in human breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347716"}
{"pmid": "4347714", "title": "Transport and metabolism of glucosamine by cultured Novikoff rat hepatoma cells and effects on nucleotide pools.", "content": "Transport and metabolism of glucosamine by cultured Novikoff rat hepatoma cells and effects on nucleotide pools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347714"}
{"pmid": "4347718", "title": "1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse.", "content": "1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347718"}
{"pmid": "4347717", "title": "In vivo effects of proteases on cell surface architecture and cell proliferation in the liver.", "content": "In vivo effects of proteases on cell surface architecture and cell proliferation in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347717"}
{"pmid": "4347719", "title": "Demonstration of common sarcoma-associated antigen(s) in an established human neurogenic sarcoma cell line.", "content": "Demonstration of common sarcoma-associated antigen(s) in an established human neurogenic sarcoma cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347719"}
{"pmid": "4347720", "title": "Enhancement of viral oncogenicity by the prior administration of dimethyl sulfoxide.", "content": "Enhancement of viral oncogenicity by the prior administration of dimethyl sulfoxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347720"}
{"pmid": "4347721", "title": "The establishment of MDMS-resistant cloned cell lines from in vitro cultured, MDMS-sensitive, Yoshida sarcoma cells.", "content": "The establishment of MDMS-resistant cloned cell lines from in vitro cultured, MDMS-sensitive, Yoshida sarcoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347721"}
{"pmid": "4347722", "title": "The effects of chemical irritants and tobacco smoke condensate on the chorioallantoic membrane of the fertile hen's egg.", "content": "The effects of chemical irritants and tobacco smoke condensate on the chorioallantoic membrane of the fertile hen's egg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347722"}
{"pmid": "4347723", "title": "Guidelines for the control of equine viral infections.", "content": "Guidelines for the control of equine viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347723"}
{"pmid": "4347726", "title": "The inhibitory action of  -aminobutyric acid, a probable synaptic transmitter.", "content": "The inhibitory action of  -aminobutyric acid, a probable synaptic transmitter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347726"}
{"pmid": "4347724", "title": "Fluid secretory response of bovine Thiry jejunal fistula to enterotoxin of Clostridium perfringens.", "content": "Fluid secretory response of bovine Thiry jejunal fistula to enterotoxin of Clostridium perfringens. The effect of enterotoxin of Clostridium perfringens type A was studied in Thiry fistula of the bovine jejunum. Accumulation of fluid as a pathological response was demonstrable within 30 min after introduction of enterotoxin into the fistula; the fluid volume increased rapidly within the first 2 hr and reached maximum in 7 hr. The enterotoxin was not destroyed by the jejunal fluid; 52% of it was absorbed in 2 to 3 hr, and all of the enterotoxin was taken up within 8 hr postinoculation. The accumulation of fluid by the fistula after 0.5 to 2 hr of exposure to enterotoxin ceased completely within 5 hr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347724"}
{"pmid": "4347725", "title": "Comparative densities of hydrolase-containing granules from normal and BCG-induced alveolar macrophages.", "content": "Comparative densities of hydrolase-containing granules from normal and BCG-induced alveolar macrophages. Compared to cells from normal rabbit lungs, BCG-induced alveolar macrophages have a marked increase in hydrolase levels and the number of large electron-dense subcellular structures. This study was performed to investigate the possibility that these electron-dense structures were responsible for the increased hydrolase levels of these cells. Using sucrose gradient centrifugation, nuclei-free homogenates of normal and BCG-induced macrophages were analyzed with respect to the subcellular particles they contain. Gradient fractions were assayed for enzymes commonly associated with lysosomes as well as the mitochondrial cytochrome oxidase. Fractions of peak hydrolase activity from the BCG-induced preparations were consistently more dense than those from the normal cell preparations. Ultrastructural studies of the particulate material found in fractions of peak hydrolase activity from BCG-induced preparations revealed the presence of electron-dense, often dumbbell-shaped, granules. The data suggest that these peculiar granules are responsible for the elevated hydrolase levels of BCG-induced alveolar macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347725"}
{"pmid": "4347727", "title": "Projection of forelimb group I muscle afferents to the cat cerebral cortex.", "content": "Projection of forelimb group I muscle afferents to the cat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347727"}
{"pmid": "4347728", "title": "Physiological pathways through the vestibular nuclei.", "content": "Physiological pathways through the vestibular nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347728"}
{"pmid": "4347729", "title": "Tetrodotoxin, saxitoxin, and related substances: their applications in neurobiology.", "content": "Tetrodotoxin, saxitoxin, and related substances: their applications in neurobiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347729"}
{"pmid": "4347730", "title": "Purification and properties of  -lactamase of pseudomonas aeruginosa.", "content": "Purification and properties of  -lactamase of pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347730"}
{"pmid": "4347731", "title": "Whooping cough in northern Israel.", "content": "Whooping cough in northern Israel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347731"}
{"pmid": "4347732", "title": "Proton nuclear magnetic resonance and electron spin resonance investigation of the electronic structure and magnetic properties of synthetic low-spin ferric porphyrins.", "content": "Proton nuclear magnetic resonance and electron spin resonance investigation of the electronic structure and magnetic properties of synthetic low-spin ferric porphyrins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347732"}
{"pmid": "4347734", "title": "Conformation of angiotensin II in aqueous solution. Evidence for the  -turn model.", "content": "Conformation of angiotensin II in aqueous solution. Evidence for the  -turn model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347734"}
{"pmid": "4347733", "title": "Proton nuclear magnetic resonance and electron spin resonance investigation of axial solvation in planar, low-spin cobalt(II) porphyrin complexes.", "content": "Proton nuclear magnetic resonance and electron spin resonance investigation of axial solvation in planar, low-spin cobalt(II) porphyrin complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347733"}
{"pmid": "4347735", "title": "Synthesis and secretion of growth hormone in the rat anterior pituitary. II. Properties of the isolated growth hormone storage granules.", "content": "Synthesis and secretion of growth hormone in the rat anterior pituitary. II. Properties of the isolated growth hormone storage granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347735"}
{"pmid": "4347736", "title": "Kinetics of unfolding and refolding of proteins. II. Results for cytochrome c.", "content": "Kinetics of unfolding and refolding of proteins. II. Results for cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347736"}
{"pmid": "4347737", "title": "Kinetics of unfolding and refolding of proteins. 3. Results for lysozyme.", "content": "Kinetics of unfolding and refolding of proteins. 3. Results for lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347737"}
{"pmid": "4347738", "title": "DNA replication of SV40-infected cells. VII. Formation of SV40 catenated and circular dimers.", "content": "DNA replication of SV40-infected cells. VII. Formation of SV40 catenated and circular dimers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347738"}
{"pmid": "4347739", "title": "Nucleotide sequences from messenger RNA transcribed from the operator-proximal portion of the tryptophan operon of Escherichia coli.", "content": "Nucleotide sequences from messenger RNA transcribed from the operator-proximal portion of the tryptophan operon of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347739"}
{"pmid": "4347740", "title": "Characterization of Simian virus 40 DNA component II during viral DNA replication.", "content": "Characterization of Simian virus 40 DNA component II during viral DNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347740"}
{"pmid": "4347741", "title": "The effect of low concentrations of L-glutamate and L-aspartate on transmitter release at the locust excitatory nerve-muscle synapse.", "content": "The effect of low concentrations of L-glutamate and L-aspartate on transmitter release at the locust excitatory nerve-muscle synapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347741"}
{"pmid": "4347743", "title": "The modification of bulbo-spinal facilitation of the monosynaptic reflex by 5-hydroxytryptamine precursors and antagonists.", "content": "The modification of bulbo-spinal facilitation of the monosynaptic reflex by 5-hydroxytryptamine precursors and antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347743"}
{"pmid": "4347742", "title": "The cerebellum as a computer: patterns in space and time.", "content": "The cerebellum as a computer: patterns in space and time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347742"}
{"pmid": "4347744", "title": "Estimation of primary sequence homology from amino acid composition of evolutionary related proteins.", "content": "Estimation of primary sequence homology from amino acid composition of evolutionary related proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347744"}
{"pmid": "4347745", "title": "Hyperbaric medicine in the US Air Force.", "content": "Hyperbaric medicine in the US Air Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347745"}
{"pmid": "4347747", "title": "Vascular catheter protection and storage devices.", "content": "Vascular catheter protection and storage devices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347747"}
{"pmid": "4347748", "title": "Implantation and use of a subcutaneous culture chamber in laboratory animals.", "content": "Implantation and use of a subcutaneous culture chamber in laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347748"}
{"pmid": "4347749", "title": "A purified gel diet for guinea pigs.", "content": "A purified gel diet for guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347749"}
{"pmid": "4347750", "title": "Intestinal microsporidiosis in Callicebus moloch.", "content": "Intestinal microsporidiosis in Callicebus moloch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347750"}
{"pmid": "4347751", "title": "Intraspecies variation in serum cholesterol levels in imported Macaca nemestrina.", "content": "Intraspecies variation in serum cholesterol levels in imported Macaca nemestrina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347751"}
{"pmid": "4347752", "title": "The surgical preparation and maintenance of pigs in biovailability studies.", "content": "The surgical preparation and maintenance of pigs in biovailability studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347752"}
{"pmid": "4347753", "title": "Housing for aquatic animals.", "content": "Housing for aquatic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347753"}
{"pmid": "4347754", "title": "Cardiac puncture in laboratory animals.", "content": "Cardiac puncture in laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347754"}
{"pmid": "4347755", "title": "Bordetella bronchiseptica in laboratory cats from central California.", "content": "Bordetella bronchiseptica in laboratory cats from central California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347755"}
{"pmid": "4347756", "title": "Staphylococcal botryomycosis in a specific-pathogen-free mouse colony.", "content": "Staphylococcal botryomycosis in a specific-pathogen-free mouse colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347756"}
{"pmid": "4347757", "title": "Spontaneous occurrence and experimental transmission of the fungus, Fonsecaea pedrosoi, in the marine toad, Bufo marinus.", "content": "Spontaneous occurrence and experimental transmission of the fungus, Fonsecaea pedrosoi, in the marine toad, Bufo marinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347757"}
{"pmid": "4347759", "title": "Postnatal development of the prairie vole, Microtus ochrogaster.", "content": "Postnatal development of the prairie vole, Microtus ochrogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347759"}
{"pmid": "4347758", "title": "Comparison of hematologic values from peripheral blood of the ear and venous blood of infant baboons (Papio cynocephalus).", "content": "Comparison of hematologic values from peripheral blood of the ear and venous blood of infant baboons (Papio cynocephalus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347758"}
{"pmid": "4347760", "title": "Maintaining frugivorous phyllostomatid bats in the laboratory: Phyllostomus, Artibeus, and Sturnira.", "content": "Maintaining frugivorous phyllostomatid bats in the laboratory: Phyllostomus, Artibeus, and Sturnira.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347760"}
{"pmid": "4347762", "title": "Experimental rubella virus infection of marmosets (Saguinus species).", "content": "Experimental rubella virus infection of marmosets (Saguinus species).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347762"}
{"pmid": "4347763", "title": "Niclosamide as a treatment for Hymenolepis nana and Hymenolepis diminuta in rats.", "content": "Niclosamide as a treatment for Hymenolepis nana and Hymenolepis diminuta in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347763"}
{"pmid": "4347761", "title": "Influence of acclimation upon rectal temperatures of rabbits subjected to controlled environmental conditions.", "content": "Influence of acclimation upon rectal temperatures of rabbits subjected to controlled environmental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347761"}
{"pmid": "4347764", "title": "Outdoor housing of nonhuman primates.", "content": "Outdoor housing of nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347764"}
{"pmid": "4347765", "title": "Intraocular pressure in the juvenile rhesus monkey (Macaca mulatta) by applanation tonometry. Preliminary report.", "content": "Intraocular pressure in the juvenile rhesus monkey (Macaca mulatta) by applanation tonometry. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347765"}
{"pmid": "4347766", "title": "The use of fetal animals to investigate renal development.", "content": "The use of fetal animals to investigate renal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347766"}
{"pmid": "4347767", "title": "Experimental kidney transplantation.", "content": "Experimental kidney transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347767"}
{"pmid": "4347768", "title": "Chemodectomas of the nasopharynx. An unusual case associated with unilateral ocular proptosis.", "content": "Chemodectomas of the nasopharynx. An unusual case associated with unilateral ocular proptosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347768"}
{"pmid": "4347769", "title": "Malignant insulinoma with hepatic secondaries treated with hepatic artery ligation.", "content": "Malignant insulinoma with hepatic secondaries treated with hepatic artery ligation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347769"}
{"pmid": "4347771", "title": "Respiratory infection which requires surgical management.", "content": "Respiratory infection which requires surgical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347771"}
{"pmid": "4347772", "title": "Hepatic ultrastructure in endotoxemia, hemorrhage, and hypoxia: emphasis on mitochondrial changes.", "content": "Hepatic ultrastructure in endotoxemia, hemorrhage, and hypoxia: emphasis on mitochondrial changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347772"}
{"pmid": "4347770", "title": "The range of carcinogenic substances in human foods and the problems of testing for them.", "content": "The range of carcinogenic substances in human foods and the problems of testing for them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347770"}
{"pmid": "4347774", "title": "Plasmid-linked tetracycline and erythromycin resistance in group D \"streptococcus\".", "content": "Plasmid-linked tetracycline and erythromycin resistance in group D \"streptococcus\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347774"}
{"pmid": "4347775", "title": "R factors identified in Paris, some conferring gentamicin resistance, constitute a new compatibility group.", "content": "R factors identified in Paris, some conferring gentamicin resistance, constitute a new compatibility group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347775"}
{"pmid": "4347777", "title": "The effect of electro-convulsive therapy on the urinary excretion of adenosine 3':5'-cyclic monophosphate.", "content": "The effect of electro-convulsive therapy on the urinary excretion of adenosine 3':5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347777"}
{"pmid": "4347778", "title": "The effect of glucagon on adenosine 3':5'-cyclic monophosphate concentrations in an organ culture of adult rat liver.", "content": "The effect of glucagon on adenosine 3':5'-cyclic monophosphate concentrations in an organ culture of adult rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347778"}
{"pmid": "4347779", "title": "Micro methods of osmometry based on the equilibrium swelling of gels.", "content": "Micro methods of osmometry based on the equilibrium swelling of gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347779"}
{"pmid": "4347781", "title": "Mechanisms for the control of enzymic rates.", "content": "Mechanisms for the control of enzymic rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347781"}
{"pmid": "4347780", "title": "Binding of rat liver and hepatoma polyribosomes to stripped rough endoplasmic reticulum in vitro. Biological or an artifact?", "content": "Binding of rat liver and hepatoma polyribosomes to stripped rough endoplasmic reticulum in vitro. Biological or an artifact? Exposed thiol groups do not appear to be related to the binding of (32)P-labelled polyribosomes to stripped rough endoplasmic reticulum in vitro. Treating stripped rough endoplasmic reticulum with GSSG did not diminish binding of polyribosomes, suggesting that binding in vitro has no correlation with the inhibition of protein synthesis in vitro reported by Kosower et al. (1971). Thiol reagents, which are known to dissociate ribosomes, did not significantly decrease binding of (32)P-labelled polyribosomes to stripped rough endoplasmic reticulum. Denaturing the protein of (32)P-labelled polyribosomes or stripped rough endoplasmic reticulum of liver or hepatoma with heat, trichloroacetic acid, or HClO(4) did not alter the binding in vitro. Therefore, the practice of measuring the binding of (32)P-labelled polyribosomes to stripped rough endoplasmic reticulum in vitro (Shires et al., 1971b) is an unsuitable indicator of biological significance in the intact cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347780"}
{"pmid": "4347782", "title": "Structure and function of liver fructose 1,6-diphosphatase.", "content": "Structure and function of liver fructose 1,6-diphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347782"}
{"pmid": "4347783", "title": "Localization of D-myoinositol 1:2-cyclic phosphate 2-phosphohydrolase in rat kidney.", "content": "Localization of D-myoinositol 1:2-cyclic phosphate 2-phosphohydrolase in rat kidney. 1. On subcellular fractionation of rat kidney homogenates by differential and density-gradient centrifugation, the bulk of the inositol 1:2-cyclic phosphate 2-phosphohydrolase activity remains with the alkaline phosphatase activity, suggesting localization in the brush borders of the proximal tubules. 2. Histochemical studies with a medium containing inositol 1:2-cyclic phosphate and Escherichia coli phosphomonoesterase show Gomori staining around the brush borders of the proximal tubules in the outer cortex only. 3. Serial sections across the kidney from cortex perimeter to papilla suggest that the inositol 1:2-cyclic phosphate 2-phosphohydrolase has a limited distribution along the proximal tubule of the nephron, probably being limited to the pars convoluta, whereas the alkaline phosphatase extends along the pars recta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347783"}
{"pmid": "4347784", "title": "Preliminary investigations on bovine hepatic fructose 1,6-diphosphatase.", "content": "Preliminary investigations on bovine hepatic fructose 1,6-diphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347784"}
{"pmid": "4347785", "title": "Spin-spin interaction between molybdenum and one of the iron-sulphur systems of xanthine oxidase and its relevance to the enzymic mechanism.", "content": "Spin-spin interaction between molybdenum and one of the iron-sulphur systems of xanthine oxidase and its relevance to the enzymic mechanism. 1. Electron-paramagnetic-resonance (e.p.r.) studies at 9 and 35GHz at helium temperatures have given new information relating to the structure and mechanism of action of xanthine oxidase. 2. As reported by others, the enzyme gives two types of e.p.r. signal attributed to iron-sulphur systems. The first has g(av.)=1.95. Parameters of the second are determined as g(1) 2.12, g(2) 2.007 and g(3) 1.91, with g(av.)=2.01. This species seems to have a slightly higher redox potential than the former one. 3. Temperature-dependent changes in the form of Mo(v) e.p.r. signals from the enzyme, observed under certain conditions, are shown to be due to weak spin-spin interaction between Mo(v) and g(av.)=1.95 Fe/S. The phenomenon has been studied most fully for the Slow Mo(v) signal. Here, the spectral change takes the form of an additional approximately isotropic 11G splitting, detected below about 45 degrees K only. Samples without Fe/S reduced showed no such changes of spectrum. 4. Similar spectral changes were observed in the Rapid Mo(v) signals, obtained in rapid-freezing experiments, but only in samples corresponding to relatively long reaction times with the substrate. It is suggested therefore that the phenomenon may provide a means of distinguishing enzyme centres with Mo only reduced from those in which both Mo and Fe/S are reduced. 5. Additional rapid-freezing data tending to support a two- rather than a one-electron transfer of reducing equivalents from substrates to xanthine oxidase are reported.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347785"}
{"pmid": "4347786", "title": "Some properties of guinea-pig liver fructose 1,6-diphosphatase in relation to the control of gluconeogenesis.", "content": "Some properties of guinea-pig liver fructose 1,6-diphosphatase in relation to the control of gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347786"}
{"pmid": "4347787", "title": "The development of some enzymes of gluconeogenesis in the liver and kidney of the foetal guinea pig.", "content": "The development of some enzymes of gluconeogenesis in the liver and kidney of the foetal guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347787"}
{"pmid": "4347788", "title": "The effect of oxygen concentration on the growth and metabolism of Saccharomyces cerevisiae grown with excess of potassium or in potassium-deficient media.", "content": "The effect of oxygen concentration on the growth and metabolism of Saccharomyces cerevisiae grown with excess of potassium or in potassium-deficient media. 1. Saccharomyces cerevisiae cells grown in limiting K(+) concentration have their growth inhibited by O(2) concentrations above 40%. With these conditions the cells grow very large and are unable to maintain ionic gradients when washed with water. 2. Cells grown in excess of K(+) showed the same pattern of change in cell size with change in O(2) concentration, but the magnitude of the changes was much less. Cells grown in excess of K(+) were not leaky. 3. Cell death, growth and development of ;leakiness' were not correlated in the cells grown in limiting K(+) concentration. 4. The activities of both alcohol dehydrogenase and cytochrome oxidase were higher in K(+)-deficient cells than in the cells grown with excess of K(+). The differences were much larger when the measurements were made on a cellular basis than when made on a protein basis. 5. In 100% O(2) 3mm-K(+) in the medium was sufficient to produce normal yeast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347788"}
{"pmid": "4347789", "title": "D- and L-lactate dehydrogenases of Pseudomonas aeruginosa.", "content": "D- and L-lactate dehydrogenases of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347789"}
{"pmid": "4347790", "title": "Metabolism of piperonylate by Pseudomonas fluorescens.", "content": "Metabolism of piperonylate by Pseudomonas fluorescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347790"}
{"pmid": "4347791", "title": "The effect of local anaesthetics on lipolysis in fat-cells.", "content": "The effect of local anaesthetics on lipolysis in fat-cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347791"}
{"pmid": "4347792", "title": "Influence of a 17 beta-sulphate group on reduction of a steroid 3-oxo group by cortisone reductase.", "content": "Influence of a 17 beta-sulphate group on reduction of a steroid 3-oxo group by cortisone reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347792"}
{"pmid": "4347793", "title": "A major influence of a 1 alpha, 2 alpha-methylene group on reduction of a steroid 3-oxo group by 2 nicotinamide-adenine dinucleotide-linked 3-hydroxy steroid oxidoreductases.", "content": "A major influence of a 1 alpha, 2 alpha-methylene group on reduction of a steroid 3-oxo group by 2 nicotinamide-adenine dinucleotide-linked 3-hydroxy steroid oxidoreductases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347793"}
{"pmid": "4347794", "title": "Functional groups in the catalysis and regulation of Escherichia coli citrate synthase.", "content": "Functional groups in the catalysis and regulation of Escherichia coli citrate synthase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347794"}
{"pmid": "4347795", "title": "The regulation of Acinetobacter sp. alpha-oxoglutarate dehydrogenase complex.", "content": "The regulation of Acinetobacter sp. alpha-oxoglutarate dehydrogenase complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347795"}
{"pmid": "4347796", "title": "Some properties of yeast isocitrate dehydrogenase.", "content": "Some properties of yeast isocitrate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347796"}
{"pmid": "4347797", "title": "Activation and phosphorylation of the subunits of phosphorylase kinase.", "content": "Activation and phosphorylation of the subunits of phosphorylase kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347797"}
{"pmid": "4347798", "title": "Temporal aspects of glucose metabolism in the rat at birth.", "content": "Temporal aspects of glucose metabolism in the rat at birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347798"}
{"pmid": "4347799", "title": "Increased phospholipid depletion alters the apparent specificity of phospholipid-dependence of glucose 6-phosphatase activity.", "content": "Increased phospholipid depletion alters the apparent specificity of phospholipid-dependence of glucose 6-phosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347799"}
{"pmid": "4347800", "title": "Rabbit heart valve basement membrane: low platelet reactivity.", "content": "Rabbit heart valve basement membrane: low platelet reactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347800"}
{"pmid": "4347804", "title": "Mitochondria and respiratory enzymes of L cells treated with actinomycin D.", "content": "Mitochondria and respiratory enzymes of L cells treated with actinomycin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347804"}
{"pmid": "4347805", "title": "Surface alterations in transformed epithelial and fibroblastic cells in culture: a disturbance of membrane degradation versus biosynthesis?", "content": "Surface alterations in transformed epithelial and fibroblastic cells in culture: a disturbance of membrane degradation versus biosynthesis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347805"}
{"pmid": "4347806", "title": "Synthesis of serum proteins by a clonal strain of rat hepatoma cells.", "content": "Synthesis of serum proteins by a clonal strain of rat hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347806"}
{"pmid": "4347807", "title": "The synthesis of surface coat materials in normal and transformed cells.", "content": "The synthesis of surface coat materials in normal and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347807"}
{"pmid": "4347808", "title": "Animalizing ability of Evans blue in embryos of Arbacia punctulata. Effect on multiple molecular forms of NAD-L-malate dehydrogenase.", "content": "Animalizing ability of Evans blue in embryos of Arbacia punctulata. Effect on multiple molecular forms of NAD-L-malate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347808"}
{"pmid": "4347809", "title": "Ultrastructural study of the action of aminopiperazines on transformed cell lines and on nervous system tissue culture.", "content": "Ultrastructural study of the action of aminopiperazines on transformed cell lines and on nervous system tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347809"}
{"pmid": "4347810", "title": "Cleavage inhibition in marine eggs by puromycin and 6-dimethylaminopurine.", "content": "Cleavage inhibition in marine eggs by puromycin and 6-dimethylaminopurine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347810"}
{"pmid": "4347811", "title": "Studies on cyclic AMP levels and phosphodiesterase activity in developing sea urchin eggs. Effects of puromycin, 6-dimethylamino purine and aminophylline.", "content": "Studies on cyclic AMP levels and phosphodiesterase activity in developing sea urchin eggs. Effects of puromycin, 6-dimethylamino purine and aminophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347811"}
{"pmid": "4347813", "title": "The pathway from the mediodorsal nucleus of thalamus to the hypothalamus in the cat.", "content": "The pathway from the mediodorsal nucleus of thalamus to the hypothalamus in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347813"}
{"pmid": "4347812", "title": "A growth factor for animal cells derived from peptone. II. Effect of the growth factor on cellular metabolism.", "content": "A growth factor for animal cells derived from peptone. II. Effect of the growth factor on cellular metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347812"}
{"pmid": "4347814", "title": "Primary afferent hyperpolarization without postsynaptic potentiation.", "content": "Primary afferent hyperpolarization without postsynaptic potentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347814"}
{"pmid": "4347815", "title": "Caudate intracellular response to thalamic and cortical inputs.", "content": "Caudate intracellular response to thalamic and cortical inputs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347815"}
{"pmid": "4347816", "title": "Intracellular responses of caudate neurons to temporally and spatially combined stimuli.", "content": "Intracellular responses of caudate neurons to temporally and spatially combined stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347816"}
{"pmid": "4347817", "title": "Convergence in the lumbar spinal cord of pathways activated by splanchnic nerve and hind limb cutaneous nerve stimulation.", "content": "Convergence in the lumbar spinal cord of pathways activated by splanchnic nerve and hind limb cutaneous nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347817"}
{"pmid": "4347818", "title": "Membrane junctions in growth and differentiation.", "content": "Membrane junctions in growth and differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347818"}
{"pmid": "4347819", "title": "Emergency medical services: new program for old problem.", "content": "Emergency medical services: new program for old problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347819"}
{"pmid": "4347821", "title": "Anti-insulin eeffect of cortisol in deep hypoglycemia of the rat: sex differences.", "content": "Anti-insulin eeffect of cortisol in deep hypoglycemia of the rat: sex differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347821"}
{"pmid": "4347822", "title": "Effects of insulin on the lipolytic system of rat fat cells.", "content": "Effects of insulin on the lipolytic system of rat fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347822"}
{"pmid": "4347820", "title": "Cytochemistry of experimental protein malnutrition in primates: effect on the spinal cord of the squirrel monkey, Saimiri sciureus.", "content": "Cytochemistry of experimental protein malnutrition in primates: effect on the spinal cord of the squirrel monkey, Saimiri sciureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347820"}
{"pmid": "4347823", "title": "Renin-angiotensin system in chronically hypophysectomized rats.", "content": "Renin-angiotensin system in chronically hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347823"}
{"pmid": "4347824", "title": "Metabolic effects of a medium-chain triglyceride emulsion injected intravenously in man.", "content": "Metabolic effects of a medium-chain triglyceride emulsion injected intravenously in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347824"}
{"pmid": "4347825", "title": "An investigation of clinical applications of mesomorphic cholesteric liquid crystals in podiatric medicine. A preliminary study.", "content": "An investigation of clinical applications of mesomorphic cholesteric liquid crystals in podiatric medicine. A preliminary study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347825"}
{"pmid": "4347826", "title": "Angiotensin II like activity in the plasma of normal subjects and patients with renal hypertension.", "content": "Angiotensin II like activity in the plasma of normal subjects and patients with renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347826"}
{"pmid": "4347827", "title": "Serum, spinal fluid and neural total lipids, phospholipids and cholesterol in diabetes mellitus and non-diabetic neuropathy.", "content": "Serum, spinal fluid and neural total lipids, phospholipids and cholesterol in diabetes mellitus and non-diabetic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347827"}
{"pmid": "4347828", "title": "Renin-angiotensin system and hypertension.", "content": "Renin-angiotensin system and hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347828"}
{"pmid": "4347829", "title": "Motility of spermatozoa and control of bacteria in bovine semen diluents contining penicillin and neomycin or epicillin.", "content": "Motility of spermatozoa and control of bacteria in bovine semen diluents contining penicillin and neomycin or epicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347829"}
{"pmid": "4347833", "title": "Molecular complexity of Paramecium symbiont lambda deoxyribonucleic acid: evidence for the presence of a multicopy genome.", "content": "Molecular complexity of Paramecium symbiont lambda deoxyribonucleic acid: evidence for the presence of a multicopy genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347833"}
{"pmid": "4347834", "title": "The typical dream: case studies.", "content": "The typical dream: case studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347834"}
{"pmid": "4347840", "title": "Respiratory smooth muscle relaxing effect of commercial steroid preparations.", "content": "Respiratory smooth muscle relaxing effect of commercial steroid preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347840"}
{"pmid": "4347830", "title": "Histopathological study of a quartz-filled composite dental restorative material.", "content": "Histopathological study of a quartz-filled composite dental restorative material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347830"}
{"pmid": "4347841", "title": "Hypertension with aldosterone excess.", "content": "Hypertension with aldosterone excess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347841"}
{"pmid": "4347842", "title": "A vista of research on the mammalian gonadotropins. Carl G. Hartman Lecture.", "content": "A vista of research on the mammalian gonadotropins. Carl G. Hartman Lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347842"}
{"pmid": "4347844", "title": "Evidence of electrotonic transmission in the vestibular nuclei of the rat.", "content": "Evidence of electrotonic transmission in the vestibular nuclei of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347844"}
{"pmid": "4347843", "title": "The cyclic AMP system of human brain.", "content": "The cyclic AMP system of human brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347843"}
{"pmid": "4347831", "title": "Subcellular distribution of NADH cytochrome c reductase in rat gingiva.", "content": "Subcellular distribution of NADH cytochrome c reductase in rat gingiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347831"}
{"pmid": "4347845", "title": "Cortical interneurons during sleep and waking in freely moving primates.", "content": "Cortical interneurons during sleep and waking in freely moving primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347845"}
{"pmid": "4347847", "title": "Some evidence for the existence of dopaminergic neurons in the rat cortex.", "content": "Some evidence for the existence of dopaminergic neurons in the rat cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347847"}
{"pmid": "4347846", "title": "Effects of serotonin metabolites on sleep-waking activity in cats.", "content": "Effects of serotonin metabolites on sleep-waking activity in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347846"}
{"pmid": "4347848", "title": "Benzodiazepines and posttetanic potentiation in sympathetic ganglia of the bullfrog.", "content": "Benzodiazepines and posttetanic potentiation in sympathetic ganglia of the bullfrog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347848"}
{"pmid": "4347849", "title": "The modification of the pupillary light reflex by chlorpromazine, diazepam, and pentobarbital.", "content": "The modification of the pupillary light reflex by chlorpromazine, diazepam, and pentobarbital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347849"}
{"pmid": "4347850", "title": "Responses of single units in the medulla to genital stimulation in estrous and anestrous cats.", "content": "Responses of single units in the medulla to genital stimulation in estrous and anestrous cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347850"}
{"pmid": "4347852", "title": "The effect of thoracic duct lymph drainage in myasthenia gravis.", "content": "The effect of thoracic duct lymph drainage in myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347852"}
{"pmid": "4347854", "title": "Influence of calcium on angiotensin II--antibody reaction.", "content": "Influence of calcium on angiotensin II--antibody reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347854"}
{"pmid": "4347855", "title": "The interaction of chaotropic anions with acid ferricytochrome c.", "content": "The interaction of chaotropic anions with acid ferricytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347855"}
{"pmid": "4347856", "title": "Fatty acid inhibition of sulfation factor-stimulated  35 SO 4  incorporation into embryonic chicken cartilage.", "content": "Fatty acid inhibition of sulfation factor-stimulated  35 SO 4  incorporation into embryonic chicken cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347856"}
{"pmid": "4347857", "title": "Regulation of fatty acid synthesis in isolated hepatocytes prepared from the livers of neonatal chicks.", "content": "Regulation of fatty acid synthesis in isolated hepatocytes prepared from the livers of neonatal chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347857"}
{"pmid": "4347858", "title": "Relation of glucagon-specific binding sites to glucagon-dependent stimulation of adenylyl cyclase activity in plasma membranes of rat liver.", "content": "Relation of glucagon-specific binding sites to glucagon-dependent stimulation of adenylyl cyclase activity in plasma membranes of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347858"}
{"pmid": "4347859", "title": "Yeast inorganic pyrophosphatase. VI. Studies on specificity and mechanism.", "content": "Yeast inorganic pyrophosphatase. VI. Studies on specificity and mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347859"}
{"pmid": "4347860", "title": "Characteristics of the human lymphocyte insulin receptor.", "content": "Characteristics of the human lymphocyte insulin receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347860"}
{"pmid": "4347862", "title": "A method for the estimation of some synthetic glucocorticosteroids in rat muscle.", "content": "A method for the estimation of some synthetic glucocorticosteroids in rat muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347862"}
{"pmid": "4347861", "title": "Control of glycogen synthase phosphatase from rat heart. The role of substrate.", "content": "Control of glycogen synthase phosphatase from rat heart. The role of substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347861"}
{"pmid": "4347863", "title": "The mystery virus. The elusive E-B virus: guilty or not guilty?", "content": "The mystery virus. The elusive E-B virus: guilty or not guilty?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347863"}
{"pmid": "4347864", "title": "The use of rivanol for the removal of nonspecific inhibitors of rubella virus haemagglutinin.", "content": "The use of rivanol for the removal of nonspecific inhibitors of rubella virus haemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347864"}
{"pmid": "4347866", "title": "Control of the tonic vibration reflex by the brain stem reticular formation in the cat.", "content": "Control of the tonic vibration reflex by the brain stem reticular formation in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347866"}
{"pmid": "4347865", "title": "Corticoreticulospinal control of the tonic vibration reflex in the cat.", "content": "Corticoreticulospinal control of the tonic vibration reflex in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347865"}
{"pmid": "4347868", "title": "The role of the contractile vacuole in the osmoregulation of Tetrahymena pyriformis.", "content": "The role of the contractile vacuole in the osmoregulation of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347868"}
{"pmid": "4347869", "title": "m-Chlorobenzhydroxyamic acid--an inhibitor of cyanide-insensitive respiration in Trypanosoma brucei.", "content": "m-Chlorobenzhydroxyamic acid--an inhibitor of cyanide-insensitive respiration in Trypanosoma brucei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347869"}
{"pmid": "4347871", "title": "Differentiation during encystment and excystment in Oxytricha fallax.", "content": "Differentiation during encystment and excystment in Oxytricha fallax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347871"}
{"pmid": "4347870", "title": "Inhibition of protein synthesis: a mechanism of amebicide action of emetine and other structurally related compounds.", "content": "Inhibition of protein synthesis: a mechanism of amebicide action of emetine and other structurally related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347870"}
{"pmid": "4347873", "title": "The chick as a laboratory model for the study of estrogen-induced hyperlipidemia.", "content": "The chick as a laboratory model for the study of estrogen-induced hyperlipidemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347873"}
{"pmid": "4347876", "title": "A sheep in a wolf's coat.", "content": "A sheep in a wolf's coat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347876"}
{"pmid": "4347875", "title": "Progress in endocrinology and metabolism. Vitamin D: current concepts.", "content": "Progress in endocrinology and metabolism. Vitamin D: current concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347875"}
{"pmid": "4347874", "title": "Genetic obesity in rats. II. The effect of food restriction on the metabolism of adipose tissue.", "content": "Genetic obesity in rats. II. The effect of food restriction on the metabolism of adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347874"}
{"pmid": "4347867", "title": "Measurement of plasma renin activity by angiotensin I radioimmunoassay: (I) an assessment of some methodological aspects.", "content": "Measurement of plasma renin activity by angiotensin I radioimmunoassay: (I) an assessment of some methodological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347867"}
{"pmid": "4347880", "title": "Current status of virological research in human leukemias and sarcomas.", "content": "Current status of virological research in human leukemias and sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347880"}
{"pmid": "4347881", "title": "Recruitment, loudness and the stapedial reflex threshold under hypnosis.", "content": "Recruitment, loudness and the stapedial reflex threshold under hypnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347881"}
{"pmid": "4347883", "title": "The oxygen uptake of alveolar and peritoneal macrophages during phagocytosis of toxic and non-toxic dust particles.", "content": "The oxygen uptake of alveolar and peritoneal macrophages during phagocytosis of toxic and non-toxic dust particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347883"}
{"pmid": "4347882", "title": "Examination of the liver using radio-active rose bengal. Clinical results of the Department of Radio-Isotopes, H.F. Verwoerd Hospital, Pretoria, 1963-1972.", "content": "Examination of the liver using radio-active rose bengal. Clinical results of the Department of Radio-Isotopes, H.F. Verwoerd Hospital, Pretoria, 1963-1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347882"}
{"pmid": "4347884", "title": "Cytomegalic inclusion disease. Pediatric grand rounds.", "content": "Cytomegalic inclusion disease. Pediatric grand rounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347884"}
{"pmid": "4347888", "title": "Malignant tumors of infancy and childhood.", "content": "Malignant tumors of infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347888"}
{"pmid": "4347887", "title": "The neuron doctrine: a revision of functional concepts.", "content": "The neuron doctrine: a revision of functional concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347887"}
{"pmid": "4347893", "title": "Enzymatic cyclization of neryl pyrophosphate to  -terpineol by cell-free extracts from peppermint.", "content": "Enzymatic cyclization of neryl pyrophosphate to  -terpineol by cell-free extracts from peppermint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347893"}
{"pmid": "4347894", "title": "Effect of metabolic inhibitors on the agglutination of tumor cells by concanavalin A and Ricinus communis agglutinin.", "content": "Effect of metabolic inhibitors on the agglutination of tumor cells by concanavalin A and Ricinus communis agglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347894"}
{"pmid": "4347895", "title": "Antiestrogens: studies using an in vitro estrogen-responsive uterine system.", "content": "Antiestrogens: studies using an in vitro estrogen-responsive uterine system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347895"}
{"pmid": "4347896", "title": "Cyclic AMP-induced differentiated neuroblastoma cells: changes in total nucleic acid and protein contents.", "content": "Cyclic AMP-induced differentiated neuroblastoma cells: changes in total nucleic acid and protein contents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347896"}
{"pmid": "4347898", "title": "The interaction of  -cyclodextrin with nucleic acid monomer units.", "content": "The interaction of  -cyclodextrin with nucleic acid monomer units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347898"}
{"pmid": "4347897", "title": ", -Methylene-adenosine-5'-triphosphate--effects of a competitive inhibitor of adenylate cyclase on cyclic AMP accumulation and lipolysis in isolated fat cells.", "content": ", -Methylene-adenosine-5'-triphosphate--effects of a competitive inhibitor of adenylate cyclase on cyclic AMP accumulation and lipolysis in isolated fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347897"}
{"pmid": "4347899", "title": "The characterization of rat kidney plasma membranes prepared by zonal centrifugation.", "content": "The characterization of rat kidney plasma membranes prepared by zonal centrifugation. 1. Plasma membranes were isolated from a 10000g-min pellet prepared from a renal cortical homogenate in 20mm-NaHCO(3) by isopycnic centrifugation in a linear sucrose gradient in an ;A'-type zonal rotor. 2. The preparation was characterized by electron microscopy, and alkaline phosphatase, 5'-nucleotidase, l-leucine beta-naphthylamidase and l-leucine p-nitroanilidase activities were found to be selectively associated with the renal plasma membrane. 3. The preparation had a high degree of purity, as indicated by the presence of low activities of marker enzymes associated with subcellular organelles. A preliminary chemical analysis indicated that the chemical composition resembled that of plasma membranes of other tissues. 4. Plasma membranes were also prepared from tubular fragments and their enzyme contents were found to be similar to those of plasma membranes prepared from cortical homogenates. 5. l-Leucine beta-naphthylamidase, l-leucine p-nitroanilidase and 5'-nucleotidase were not enriched to the same extent as alkaline phosphatase in the preparation of plasma membranes from tubular fragments. A possible explanation for this finding is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347899"}
{"pmid": "4347900", "title": "The role of adenosine 3':5'-cyclic monophosphate in the regulation of insulin release. Properties of islet-cell adenosine 3':5'-cyclic monophosphate phosphodiesterase.", "content": "The role of adenosine 3':5'-cyclic monophosphate in the regulation of insulin release. Properties of islet-cell adenosine 3':5'-cyclic monophosphate phosphodiesterase. 1. An assay has been developed with sufficient sensitivity for determination of the adenosine 3':5'-cyclic monophosphate diesterase activity in islets of Langerhans, and has been used to investigate the response of the enzyme to various agents which are known to affect insulin release. 2. The subcellular distribution of the enzyme in islets of Langerhans prepared from guinea-pig pancreas was investigated and over 70% of the activity present in the original homogenate was recovered in the supernatant fraction. 3. Gel filtration of the activity present in the supernatant fraction on Sephadex G-200 gave a single peak of activity with an apparent molecular weight of 200000. The phosphodiesterase activity in the peak fraction showed two apparent K(m) values for adenosine 3':5'-cyclic monophosphate (cyclic AMP) of 3mum and 30mum, suggesting the presence of two activities. The pH optimum of the activity with the low K(m) value was 8.7. 4. Theophylline, caffeine, 3-isobutyl-1-methylxanthine (SC-2964), glibenclamide, tolbutamide, xylitol and leucine were inhibitors of the activity with the low K(m) value; imidazole and arginine stimulated the activity, and glucose and diazoxide were without significant effect. 5. It is suggested that the agents theophylline, caffeine, SC-2964, glibenclamide, tolbutamide, leucine and imidazole may alter the intracellular concentration of cyclic AMP in islets of Langerhans by affecting the cyclic AMP phosphodiesterase activity in islet cells and in this way may affect insulin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347900"}
{"pmid": "4347901", "title": "The effect of two inhalation anesthetics on the order of spin-labeled phospholipid vesicles.", "content": "The effect of two inhalation anesthetics on the order of spin-labeled phospholipid vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347901"}
{"pmid": "4347902", "title": "Pressure reversal of inhalation anesthetic-induced disorder in spin-labeled phospholipid vesicles.", "content": "Pressure reversal of inhalation anesthetic-induced disorder in spin-labeled phospholipid vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347902"}
{"pmid": "4347903", "title": "Membrane fractions from rat hepatoma. II. Immunochemical characterization of detergent-soluble membrane esterases, glycosidases and leucyl- -naphthylamidase.", "content": "Membrane fractions from rat hepatoma. II. Immunochemical characterization of detergent-soluble membrane esterases, glycosidases and leucyl- -naphthylamidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347903"}
{"pmid": "4347905", "title": "Levels of membrane marker enzyme activity in normal and RNA and DNA virus-transformed fibroblasts.", "content": "Levels of membrane marker enzyme activity in normal and RNA and DNA virus-transformed fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347905"}
{"pmid": "4347906", "title": "Respiratory viral infections in hospital patients with chronic bronchitis. Observations during periods of exacerbation and quiescence.", "content": "Respiratory viral infections in hospital patients with chronic bronchitis. Observations during periods of exacerbation and quiescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347906"}
{"pmid": "4347904", "title": "Membrane fractions from rat hepatoma. 3. Immunochemical characterization of detergent-soluble membrane phosphatases, electron transport chains and catalase.", "content": "Membrane fractions from rat hepatoma. 3. Immunochemical characterization of detergent-soluble membrane phosphatases, electron transport chains and catalase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347904"}
{"pmid": "4347908", "title": "Pulmonary blastoma; longterm survival of juvenile patient.", "content": "Pulmonary blastoma; longterm survival of juvenile patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347908"}
{"pmid": "4347909", "title": "Three simultaneous multiple primary carcinomas in one patient.", "content": "Three simultaneous multiple primary carcinomas in one patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347909"}
{"pmid": "4347907", "title": "Nomenclature explosion.", "content": "Nomenclature explosion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347907"}
{"pmid": "4347910", "title": "An appraisal of routine methods for the determination of the anodal isoenzymes of lactate dehydrogenase.", "content": "An appraisal of routine methods for the determination of the anodal isoenzymes of lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347910"}
{"pmid": "4347911", "title": "The role of cyclic AMP and calcium in cell activation.", "content": "The role of cyclic AMP and calcium in cell activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347911"}
{"pmid": "4347913", "title": "The relationship of the level of cyclic amp to differentiation in primary cultures of chick muscle cells.", "content": "The relationship of the level of cyclic amp to differentiation in primary cultures of chick muscle cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347913"}
{"pmid": "4347914", "title": "Effect of 5-bromodeoxyuridine on the structure of differentiating choroid plexus cells in vitro.", "content": "Effect of 5-bromodeoxyuridine on the structure of differentiating choroid plexus cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347914"}
{"pmid": "4347915", "title": "Stable alterations in HeLa cell mitochondria following ethidium bromide treatment.", "content": "Stable alterations in HeLa cell mitochondria following ethidium bromide treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347915"}
{"pmid": "4347916", "title": "A quantitation of movement of marker particles in the plasma membrane of 3T3 mouse fibroblasts. Experimental methods.", "content": "A quantitation of movement of marker particles in the plasma membrane of 3T3 mouse fibroblasts. Experimental methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347916"}
{"pmid": "4347917", "title": "A quantitative difference in the movement of marker particles in the plasma membrane of 3T3 mouse fibroblasts and their polyoma transformants.", "content": "A quantitative difference in the movement of marker particles in the plasma membrane of 3T3 mouse fibroblasts and their polyoma transformants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347917"}
{"pmid": "4347919", "title": "Cystosarcoma phyllodes.", "content": "Cystosarcoma phyllodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347919"}
{"pmid": "4347920", "title": "Problems peculiar to brain malignancies.", "content": "Problems peculiar to brain malignancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347920"}
{"pmid": "4347921", "title": "Secondary carcinomatous deposits in the skeletal muscles in association with non-metastatic carcinomatous neuromyopathy.", "content": "Secondary carcinomatous deposits in the skeletal muscles in association with non-metastatic carcinomatous neuromyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347921"}
{"pmid": "4347922", "title": "Absolute configuration of a metabolite in the m-fission pathway of protocatechuate.", "content": "Absolute configuration of a metabolite in the m-fission pathway of protocatechuate. An aldolase, which is induced in Pseudomonas testosteroni during growth with p-hydroxybenzoate, preferentially attacks the R form of 4-hydroxy-4-methyl-2-oxoglutarate, a metabolite of protocatechuate catabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347922"}
{"pmid": "4347923", "title": "Membrane lipids of Mycoplasma hominis.", "content": "Membrane lipids of Mycoplasma hominis. Essentially all of the lipids of Mycoplasma hominis (200 mug/mg of cell protein) were found to be located in the cell membrane. Over one-half were neutral lipids incorporated from the growth medium and consisting of 43% free cholesterol, 19% esterified cholesterol, 23% triglycerides, 10% free fatty acids, and small amounts of di- and monoglycerides. The polar lipids accounting for about 40% of the total were synthesized by the organisms. Phosphatidylglycerol was the predominant lipid of this fraction. The minor components, tentatively identified as lysophosphatidylglycerol and phosphatidic acid, seem to represent breakdown products of phosphatidylglycerol. No glycolipids were detected. Being unable to synthesize long-chain fatty acids, M. hominis utilized the fatty acids of the growth medium for polar lipid synthesis, preferentially the saturated ones, so that the polar lipids had highly saturated hydrocarbon chains. It is proposed that the large take up of unsaturated neutral lipids and cholesterol from the medium offsets the marked condensing effect of the saturated polar lipids, although electron paramagnetic resonance spectrometry of spin-labeled fatty acids incorporated into the M. hominis membrane indicated that the lipid region is still more rigid than that of the Acholeplasma laidlawii membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347923"}
{"pmid": "4347925", "title": "Chromatographically fractionated complementary strands of Bacillus subtilis deoxyribonucleic acid: biological properties.", "content": "Chromatographically fractionated complementary strands of Bacillus subtilis deoxyribonucleic acid: biological properties. Biological, physical, and chromatographic properties of methylated albuminkieselguhr (MAK)-fractionated complementary strands, designated as light (L) and heavy (H), of Bacillus subtilis deoxyribonucleic acid (DNA) are presented. The pattern of transforming activity along the MAK elution profile of alkilidenatured DNA shows that the residually active molecules selectively fractionated ahead of the L strand fraction, whereas the most active self-annealed molecules fractionated preferentially at the trailing end of the H strand fraction. The restoration rate of transforming activity in the late-eluting H molecules was rapid and independent of concentration during the annealing reaction. The data suggest that the self-annealing activity in the H strand is due in part to the formation of intrastrand secondary structures. Hydroxyapatite chromatography of self-annealed L and H strands yielded a major fraction (I) of highly purified strand preparations devoid of transforming activity and hypochromicity, and a minor \"nativelike\" fraction (II). Sedimentation velocity measurements show that, in addition to the mutual complementary nature of the L and H fractions, they differ in molecular size and possibly configuration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347925"}
{"pmid": "4347924", "title": "Control of pantothenate accumulation in Agrobacterium tumefaciens.", "content": "Control of pantothenate accumulation in Agrobacterium tumefaciens. Two pantothenate-requiring mutants of Agrobacterium tumefaciens have been isolated. One of them (strain WMP-1) is unusual in that growth levels equivalent to the parent strain are achieved only when the medium is additionally supplemented with aspartate or another compound related to the tricarboxylic acid cycle. Extracts of cells grown on limiting aspartate were found to contain four times more (14)C-pantothenate than those grown at optimal aspartate concentrations. This difference was found in both the perchloric acid-soluble and -insoluble fractions, presumably the coenzyme A pool and acyl carrier protein, respectively. These findings are discussed in terms of membrane integrity and the control of fatty acid biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347924"}
{"pmid": "4347926", "title": "Chromatographically fractionated complementary strands of Bacillus subtilis deoxyribonucleic acid: transformation of hybrids.", "content": "Chromatographically fractionated complementary strands of Bacillus subtilis deoxyribonucleic acid: transformation of hybrids. The annealing properties as measured by the restoration of transforming activity and hypochromicity of methylated albumin-kieselguhr (MAK)-fractionated complementary strands of Bacillus subtilis deoxyribonucleic acid (DNA) are presented. Temperature-absorbance measurements performed on annealed mixtures of various L and H strand fractions indicated the existence of a complementarity gradient between the two MAK peaks. The markers purA16, leu-8, metB(5), thr-5, and the linked marker hisB(2)-try-2 exhibited different bimodal distributions on MAK columns. The transforming efficiency of heteroduplex mixtures, prepared by cross-annealing resolved complementary strands of wild-type and recipient DNA, was compared. The transforming efficiency of the wild-type L and H strands was equal in one preparation and unequal in a second preparation. It was found that in the second strand preparation the heteroduplex DNA containing the H strand from wild type was more efficient for all of the markers tested. The variations in transforming efficiencies of the complementary strands in heteroduplex molecules reported here and by others are due in part to strands of unequal length and probably to the self-annealing property of the H strands. At present, no conclusion could be made regarding the existence of strand selection bias during integration of donor DNA in competent B. subtilis cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347926"}
{"pmid": "4347927", "title": "Role of adenosine 3',5'-cyclic monophosphate and its specific binding protein in the regulation of D-serine deaminase synthesis.", "content": "Role of adenosine 3',5'-cyclic monophosphate and its specific binding protein in the regulation of D-serine deaminase synthesis. Adenosine 3',5'-cyclic monophosphate (cyAMP) and the cyAMP-binding protein are necessary for efficient induction of d-serine deaminase (Dsdase) synthesis in dsdC(+)dsdO(+) and dsdC dsdO(+) strains of Escherichia coli K-12, and for constitutive synthesis in dsdC dsdO(+) strains. Neither is required in dsdO strains, confirming previous indications that in dsdO mutants Dsdase synthesis is not subject to catabolite repression control. Since efficient Dsdase synthesis in dsdC(+) and dsdC strains that are dsdO(+) requires the cyAMP-binding protein, which acts at the level of transcription in other systems, it is concluded that catabolite repression acts at the level of transcription of the Dsdase structural gene. Since catabolite repression is reversed by the inducer, d-serine in dsdC dsdO(+) strains, it is concluded that induction also acts at the level of transcription in this system. The dsdC strains were found to be much more sensitive to induction by d-serine than are dsdC(+) strains under conditions of catabolite repression, whether the repression was caused by glucose or by loss of ability to form cyAMP or cyAMP-binding protein. This suggests that a d-serine-dsdC complex may be able to replace partially the cyAMP:cyAMP-binding protein action in initiation of Dsdase messenger ribonucleic acid synthesis-a positive control effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347927"}
{"pmid": "4347928", "title": "Isolation and characterization of mutations affecting the transport of hexose phosphates in Escherichia coli.", "content": "Isolation and characterization of mutations affecting the transport of hexose phosphates in Escherichia coli. Mutants of Escherichia coli defective in the hexose phosphate transport system were isolated. Negative selection by penicillin treatment or positive selection with phosphonomycin was employed. These mutants grew normally on all carbon sources other than hexose phosphates. The map location of the mutations in 18 independently isolated mutant strains was investigated by transduction crosses. All of the mutations were found to lie in the same region of the chromosome, in the region represented by min 72 on the Taylor map. The order of the genes in this region was found to be mtl-cysE-pyrE-uhp-bgl-ilv. Revertants of some of the mutants exhibited altered regulatory control of this transport system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347928"}
{"pmid": "4347929", "title": "Metabolism of D-fructose by Arthrobacter pyridinolis.", "content": "Metabolism of D-fructose by Arthrobacter pyridinolis. Previous studies showed that Arthrobacter pyridinolis can transport and utilize d-glucose only after prior growth on certain Krebs cycle intermediates. In contrast, we found that d-fructose was taken up and metabolized by A. pyridinolis without special prior conditions of growth. d-Fructose was first converted to d-fructose-1-phosphate by a phosphoenolpyruvate (PEP):D-fructose phosphotransferase. This activity required both supernatant and pellet fractions from d-fructose-grown cells centrifuged at 150,000 x g. The d-fructose-1-phosphate formed was converted to d-fructose-1, 6-diphosphate. Mutants deficient in PEP:d-fructose phosphotransferase and d-fructose-1-phosphate kinase, or d-fructose-1, 6-diphosphatase (FDPase) were unable to grow on d-fructose but retained the normal ability to use d-glucose. Mutants forming reduced amounts of FDPase were completely unable to grow on d-fructose but were still capable of limited growth on Krebs cycle intermediates. A requirement for higher levels of FDPase for growth on d-fructose than for growth on Krebs cycle intermediates was also indicated by the higher specific activities of FDPase in d-fructose-grown cells than in cells grown on l-malate or amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347929"}
{"pmid": "4347930", "title": "Time of enterotoxin formation and release during sporulation of Clostridium perfringens type A.", "content": "Time of enterotoxin formation and release during sporulation of Clostridium perfringens type A. Clostridium perfringens enterotoxin was detected intracellularly about 3 hr after the inoculation of vegetative cells into sporulation medium. The subsequent increase in intracellular enterotoxin concentration roughly paralleled but followed by 2.5 to 5 hr the increase in number of heat-resistant spores. The increase in biologically active toxin coincided with the increase in enterotoxin antigen. Enterotoxin was released from the sporangium with its lysis, concomitantly with the mature spore release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347930"}
{"pmid": "4347931", "title": "A comparison of two methods of prognostic typing in breast cancer.", "content": "A comparison of two methods of prognostic typing in breast cancer. The value of two different systems for the prognostic assessment of breast cancer has been tested by comparing a group of 74 long-term survivors with a group of 54 short-term survivors. The system devised by Bloom and Richardson (1957) gave a good general correlation with prognosis. Appearances described by Harveit (1971) showed some correlation with prognosis but were rarely seen in our cases. The degree of lympho-plasmacytic infiltrate did not show any correlation with prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347931"}
{"pmid": "4347933", "title": "Effects of reserpine on sleep and brain biogenic amine levels in the cat.", "content": "Effects of reserpine on sleep and brain biogenic amine levels in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347933"}
{"pmid": "4347934", "title": "Juvenile nasopharyngeal haemangiofibroma.", "content": "Juvenile nasopharyngeal haemangiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347934"}
{"pmid": "4347938", "title": "Herpes simplex and zoster.", "content": "Herpes simplex and zoster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347938"}
{"pmid": "4347939", "title": "Actinomycin D for Wilms's tumour.", "content": "Actinomycin D for Wilms's tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347939"}
{"pmid": "4347940", "title": "Oral contraceptives.", "content": "Oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347940"}
{"pmid": "4347941", "title": "Physiological and genetic studies of polyoma virus.", "content": "Physiological and genetic studies of polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347941"}
{"pmid": "4347944", "title": "Pseudo-cowpox (paravaccinia) in dairy cows.", "content": "Pseudo-cowpox (paravaccinia) in dairy cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347944"}
{"pmid": "4347949", "title": "Bronchography in diseases of the adult chest.", "content": "Bronchography in diseases of the adult chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347949"}
{"pmid": "4347950", "title": "Radiographic aspects of pulmonary infection in patients with altered immunity.", "content": "Radiographic aspects of pulmonary infection in patients with altered immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347950"}
{"pmid": "4347956", "title": "Maternal-fetal endocrine interrelations: influence of maternal adrenocorticosteroids on fetal ACTH secretion.", "content": "Maternal-fetal endocrine interrelations: influence of maternal adrenocorticosteroids on fetal ACTH secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347956"}
{"pmid": "4347957", "title": "Angiotensin II, diuretics, and thoracic duct lymph flow in the dog.", "content": "Angiotensin II, diuretics, and thoracic duct lymph flow in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347957"}
{"pmid": "4347958", "title": "Cheap labor from poor nations.", "content": "Cheap labor from poor nations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347958"}
{"pmid": "4347959", "title": "Stimulation of aldosterone secretion by hemorrhage in dogs after nephrectomy and decapitation.", "content": "Stimulation of aldosterone secretion by hemorrhage in dogs after nephrectomy and decapitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347959"}
{"pmid": "4347960", "title": "Roentgen evaluation of Wilms' tumor.", "content": "Roentgen evaluation of Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347960"}
{"pmid": "4347961", "title": "Synthesis of cyclic AMP and phosphodiesterase in various species of cellular slime molds and its bearing on chemotaxis and differentiation.", "content": "Synthesis of cyclic AMP and phosphodiesterase in various species of cellular slime molds and its bearing on chemotaxis and differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347961"}
{"pmid": "4347962", "title": "Metabolism of ethanol and fructose in the isolated perfused pig liver.", "content": "Metabolism of ethanol and fructose in the isolated perfused pig liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347962"}
{"pmid": "4347963", "title": "A sequence of 50 nucleotides from coliphage R17 RNA.", "content": "A sequence of 50 nucleotides from coliphage R17 RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347963"}
{"pmid": "4347964", "title": "Chemodectoma with metastasis to bone in a dog.", "content": "Chemodectoma with metastasis to bone in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347964"}
{"pmid": "4347965", "title": "Metabolism of phenol and cresols by mutants of Pseudomonas putida.", "content": "Metabolism of phenol and cresols by mutants of Pseudomonas putida. Mutant strains of Pseudomonas putida strain U have been obtained which are deficient in enzymes of the degradative pathways of phenol and cresols. Mutant strains deficient in catechol 2, 3-oxygenase accumulated the appropriate catechol derivative from cresols. A mutant strain which would not grow on either phenol or a cresol was shown to be deficient in both 2-hydroxymuconic semialdehyde hydrolase and a nicotinamide adenine dinucleotide, oxidized form, (NAD(+))-dependent aldehyde dehydrogenase. When this strain was grown in the presence of phenol or a cresol, the appropriate product of meta fission of these compounds accumulated in the growth medium. A partial revertant of this mutant strain, which was able to grow on ortho- and meta-cresol but not para-cresol, was shown to have regained only the hydrolase activity. This strain was used to show that the products of meta ring fission of the cresols and phenol are metabolized as follows: (i) ortho- and meta-cresol exclusively by a hydrolase; (ii) para-cresol exclusively by a NAD(+)-dependent aldehyde dehydrogenase; (iii) phenol by both a NAD(+)-dependent dehydrogenase and a hydrolase in the approximate ratio of 5 to 1. This conclusion is supported by the substrate specificity and enzymatic activity of the hydrolase and NAD(+)-dependent aldehyde dehydrogenase enzymes of the wild-type strain. The results are discussed in terms of the physiological significance of the pathway. Properties of some of the mutant strains isolated are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347965"}
{"pmid": "4347966", "title": "Salmonella typhimurium mutants lacking ribonuclease I: effect on the polarity of histidine mutants.", "content": "Salmonella typhimurium mutants lacking ribonuclease I: effect on the polarity of histidine mutants. Mutants of Salmonella typhimurium containing 1 to 2% of wild-type ribonuclease I activity were isolated. The rns mutation had no effect on the polarity of mutations in the S. typhimurium histidine operon. Even in the presence of an rns mutation, it was not possible to obtain strong suppressors of the polarity of two polar mutations in the his operon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347966"}
{"pmid": "4347967", "title": "Purification and identification of the fruiting-inducing substances in Coprinus macrorhizus.", "content": "Purification and identification of the fruiting-inducing substances in Coprinus macrorhizus. Substances which are effective in inducing fruiting bodies in monokaryotic mycelia of the fis(+) strain of Coprinus macrorhizus were purified and characterized. The active components of fruiting-inducing substances were identified as adenosine-3'-monophosphate, adenosine 3',5'-cyclic monophosphate (cyclic AMP), and a protein which is bound with the cyclic AMP. Cyclic AMP was synthesized from adenine within mycelia of the mutant strains which form monokaryotic fruiting bodies without the addition of fruiting-inducing substances, but not in those of the strains which do not form monokaryotic fruiting bodies. The proteins which bind with cyclic AMP were detected in crude extracts of mycelia of those strains which form monokaryotic fruiting bodies and of the dikaryon, but not in those of the strains which do not form monokaryotic fruiting bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347967"}
{"pmid": "4347968", "title": "Metabolism of adenosine 3',5'-cyclic monophosphate and induction of fruiting bodies in Coprinus macrorhizus.", "content": "Metabolism of adenosine 3',5'-cyclic monophosphate and induction of fruiting bodies in Coprinus macrorhizus. The adenyl cyclase and phosphodiesterase metabolizing adenosine 3',5'-cyclic monophosphate (cyclic AMP) were detected in mycelia of strains of Coprinus macrorhizus which form fruiting bodies, but not in those of strains which do not form fruiting bodies. The adenyl cyclase synthesized cyclic AMP from adenosine triphosphate. The phosphodiesterase degr[UNK]ded cyclic AMP to adenosine-5'-monophosphate and was inhibited by adenosine-3'-monophosphate, theophylline, and caffeine. The strains which form fruiting bodies incorporated and metabolized cyclic AMP, but strains which do not form fruiting bodies did not. The possible participation of cyclic AMP in the induction of fruiting bodies is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347968"}
{"pmid": "4347969", "title": "Sequential metabolic events during encystment of Azobacter vinelandii.", "content": "Sequential metabolic events during encystment of Azobacter vinelandii. Cells of Azotobacter vinelandii are specifically induced to encyst by beta-hydroxybutyrate (BHB). The process of differentiation, which occurs over a period of 36 h, was characterized by an ordered sequence of biochemical events. Upon initiation of encystment, nitrogen fixation and glucose-6-phosphate dehydrogenase activities decreased immediately to very low levels. This was followed by an increase in the specific activities of BHB dehydrogenase, isocitrate dehydrogenase, isocitrate lyase, and malate synthase first at 3 h and then again at 21 h. The peak activity of fructose 1,6-diphosphate aldolase occurred at 6 h, and the enzyme activity then decreased gradually. Fructose 1,6-diphosphatase had peak activities at 9 and 27 h. Deoxyribonucleic acid synthesis ceased just prior to the final cell division at 4 to 6 h, but ribonucleic acid synthesis continued until the 12th h. From labeling studies and the appearance of new enzyme activities, it appeared that protein synthesis continued throughout encystment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347969"}
{"pmid": "4347970", "title": "Proton magnetic resonance spectroscopy of Klebsiella capsular polysaccharides.", "content": "Proton magnetic resonance spectroscopy of Klebsiella capsular polysaccharides. The presence of acetate and pyruvate groups in Klebsiella capsular polysaccharides may be demonstrated and estimated quantitatively by running the proton magnetic resonance spectrum of the polysaccharide (as sodium salt) in deuterium oxide at 95 C. Such spectra also permit an assessment to be made of the number of alpha- and beta-linkages in the repeat unit of the polysaccharide structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347970"}
{"pmid": "4347971", "title": "Regulation of manganese accumulation and exchange in Bacillus subtilis W23.", "content": "Regulation of manganese accumulation and exchange in Bacillus subtilis W23. An overnight culture of Bacillus subtilis W23 in low-manganese tryptone broth is unable to sporulate and becomes hyperactive with regard to the manganese active transport system during stationary phase. When manganese is added to cells in spent or fresh medium, the cells immediately accumulate a high proportion of the manganese available in the medium. When the hyperactive cells are diluted into broth containing 10 muM Mn(2+), high intracellular manganese levels are reached, and inhibition of ribonucleic acid and protein synthesis occurs. This inhibition is relieved when the intracellular manganese concentration declines to the nontoxic levels characteristic of cells growing in 10 muM Mn(2+). The release of the accumulated manganese is achieved by a reduction in the uptake rate for manganese while the efflux rate remains essentially constant. Inhibitors of ribonucleic acid and protein synthesis prevent the reduction of the high rate of manganese uptake and, therefore, high net concentrations of manganese are maintained in the presence of these inhibitors. The hyperactive manganese uptake system is temperature dependent and inhibited by cyanide and m-chlorophenyl carbonylcyanide hydrazone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347971"}
{"pmid": "4347973", "title": "Fine structure of Cryptococcus neoformans grown in vitro as observed by freeze-etching.", "content": "Fine structure of Cryptococcus neoformans grown in vitro as observed by freeze-etching. Cryptococcus neoformans grown on culture media was observed by the freeze-etching technique. In the capsule, short fibrils were seen when freezeetched. This organism was unique in the appearance of the cell wall, which showed two strata. The outer one was dense with particles of about 20 nm in diameter, whereas the inner one was sparse in particles. The appearance of the cell membrane of this organism differed distinctly depending on the culture media. When grown on glycerol medium, the cell membrane possessed, as do other yeasts, clear but somewhat longer and curved invaginations. The membrane of cells grown on nonglycerol medium exhibited, however, only a few invaginations of irregular shape. Instead, characteristically of this organism, the cell membrane showed round depressions of 40 to 200 nm in diameter which were the surface view of the paramural bodies. In cross-fractured cells, both types of paramural bodies were found. Some of them contained a single vesicle of about 50 nm in diameter. These seem to play a role in secreting the cytoplasmic vesicles. Data suggesting the existence of multivesicular bodies in the cytoplasm and multivesicular lomasomes were also obtained. Some of the baglike paramural bodies showed multilayered membrane. These are thought to be plasmalemmasomes. This organism was similar to other yeasts reported in other respects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347973"}
{"pmid": "4347972", "title": "Requirement of adenosine-3',5'-cyclic monophosphate for L-arabinose isomerase synthesis in Escherichia coli.", "content": "Requirement of adenosine-3',5'-cyclic monophosphate for L-arabinose isomerase synthesis in Escherichia coli. Adenosine-3', 5'-cyclic monophosphate (cyclic AMP) is essential for the synthesis of l-arabinose isomerase in Escherichia coli. Cyclic AMP appears to be required for the transcription of deoxyribonucleic acid into messenger ribonucleic acid (RNA), since the enzyme synthesis is not observed in induced cells to which cyclic AMP is added after messenger RNA synthesis is arrested by rifampin or after inducer removal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347972"}
{"pmid": "4347974", "title": "Cyclic-nucleotide phosphodiesterase: an early defect in inherited retinal degeneration of C3H mice.", "content": "Cyclic-nucleotide phosphodiesterase: an early defect in inherited retinal degeneration of C3H mice. Cyclic nucleotides have been implicated in the differentiation and function of the vertebrate retina. In the normal retina of DBA mice, the specific activity of cyclic-nucleotide phosphodiesterase (PDE), with cyclic-AMP as the substrate (cAMP-PDE), increases eightfold between the 6th and 20th postnatal day. Kinetic analysis of retinae from newborn mice reveals a PDE with a single Michaelis constant (K(m)) value for cyclic-AMP (low K(m)-PDE). After the 6th postnatal day, a second PDE with a high K(m) for cyclic-AMP (high K(m)-PDE) can be demonstrated. The appearance and increasing activity of the high K(m)-PDE coincides with the differentiation and growth of photoreceptor outer segments. Additionally, the high K(m)-PDE is shown by microchemical techniques to be concentrated in the photoreceptor cell layer and the low K(m)-PDE within the inner layers of the normal retina. In C3H mice afflicted with an inherited degeneration of the photoreceptor layer, the postnatal increase in the specific activity of cAMP-PDE is substantially lower than in the normal retina. The postnatal increase in the specific activity of cAMP-PDE in two regions of the brain of C3H mice is the same as in the normal strain. A deficiency in high K(m)-PDE activity in the C3H retina is evident on the 7th postnatal day, when the activity of low K(m)-PDE, photoreceptor morphology, and rhodopsin content of these retina are essentially normal. In the adult C3H retina, the PDE activity with cyclic-GMP and cyclic-UMP as substrates is significantly below that of the normal retina. These data indicate that an alteration in cyclic-AMP metabolism occurs before photoreceptor cell degeneration in the retinae of C3H mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347974"}
{"pmid": "4347976", "title": "Cell membrane resorption in the rat exocrine pancreas cell after in vivo stimulation of the secretion, as studied by in vitro incubation with extracellular space markers.", "content": "Cell membrane resorption in the rat exocrine pancreas cell after in vivo stimulation of the secretion, as studied by in vitro incubation with extracellular space markers. Pancreatic secretion in the rat was stimulated in vivo by pilocarpine injection causing 90% of the storage granules to be discharged within 2 h. Incubation in vitro with [(14)C]sorbitol indicated that maximal ingestion of this extracellular space marker occurred 3 h after secretogogue injection. Morphological cell membrane measurements on cells with stimulated secretion revealed a simultaneous decrease in amount of membrane bordering the microvilli at the cell apex, lamellar processes, and infoldings present at the latero-basal face of these cells. In 3-h stimulated cells, having the average zymogen granule content characteristic for that phase of secretion, ferritin treatment in vitro showed that the infoldings and related fragmentation vesicles had ingested ferritin and could consequently be considered as being transport vehicles for redundant cell membrane. During stimulated secretion numerous vesicles and vacuoles appeared in the apical cytoplasm. Part of these structures were postulated to be related to the Golgi complex and were discussed in relation to secretory protein transport. Another part of these structures was assumed to have an endocytotic nature, although they never contained ferritin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347976"}
{"pmid": "4347975", "title": "Growth of normal and transformed rat embryo fibroblasts: effects of glycolipids from Salmonella minnesota R mutants.", "content": "Growth of normal and transformed rat embryo fibroblasts: effects of glycolipids from Salmonella minnesota R mutants. Addition of glycolipids obtained from Salmonella minnesota R mutants to normal, spontaneously transformed, and SV40-transformed rat embryo fibroblasts in culture results in an inhibition of growth of transformed cells but not of normal cells. In the presence of the glycolipid with the smallest carbohydrate chain length, spontaneously transformed cells stop growing when they reach confluency. Inhibition of growth of transformed cells is inversely related to the chain length of the core sugars. Glycolipid mR595 is shown to bind with the cell membrane of transformed cells and elicits an augmentation in the intracellular level of cyclic AMP. Normal cells bind relatively less glycolipid mR595 and show a lower percent of increase in cyclic AMP due to glycolipid mR595 than do transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347975"}
{"pmid": "4347978", "title": "Membrane fusion during mast cell secretion.", "content": "Membrane fusion during mast cell secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347978"}
{"pmid": "4347977", "title": "Secretion of collagen by corneal epithelium. I. Morphology of the collagenous products produced by isolated epithelia grown on frozen-killed lens.", "content": "Secretion of collagen by corneal epithelium. I. Morphology of the collagenous products produced by isolated epithelia grown on frozen-killed lens. Corneal epithelium from 5-7-day old chick embryos was isolated with EDTA and grown in culture on frozen-killed lens as a substratum. Autoradiographs showed that in the presence of [(3)H]proline, the corneal epithelium synthesized and secreted onto the lens substratum, radioactive materials resistant to extraction by sodium hydroxide. The radioactive label was associated with newly formed striated collagen fibrils, large \"sheets\" of collagen, and basal lamina. The repeat period and interband pattern of the abundant new collagen sheets and fibrils was typical of \"native\" or so-called \"mesenchymal\" collagen. Collagen-like materials were observed in secretory (Golgi) vacuoles within the corneal cells and collagen fibrils within the intercellular canals (lateral interfaces) of the epithelium, as well as at the base of the cells. Both the granular endoplasmic reticulum and Golgi complexes were highly developed in the corneal epithelium. In the discussion, the role of cytoplasmic organelles in collagen secretion, the origin and structure of the basal lamina, and variations in collagen polymerization patterns in vitro are reviewed and evaluated. The morphogenetic significance of the synthesis and secretion of collagen by embryonic epithelium is appraised and the production of true native-striated collagen by epithelium is stressed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347977"}
{"pmid": "4347979", "title": "Dimethyl sulfoxide-induced reversion of several features of polyoma transformed baby hamster kidney cells (BHK-21). Alterations in growth and morphology.", "content": "Dimethyl sulfoxide-induced reversion of several features of polyoma transformed baby hamster kidney cells (BHK-21). Alterations in growth and morphology. Cells of a polyoma virus transformed clonal line (Cl-I) of baby hamster kidney fibroblasts (BHK-21) were grown in medium containing 2 percent dimethylsulfoxide (DMSO). Unlike the untransformed BHK-21 cells, Cl-I cells adapted to replication in the presence of DMSO, and they exhibited a rapidly reversible phenotypic reversion of a number of properties characteristic of the transformed state. Restoration of density dependent growth inhibition with accumulation of cells in the G(1) phase of the cell cycle occurred and was associated with restoration of contact dependent behavior and with reversion of histological and ultrastructural features towards those which characterize untransformed cells. Concomitantly, Cl-I cells grown in 2 percent DMSO lost the ability to form colonies in semisolid medium. The data presented suggest that DMSO alters the expression of cellular functions which were altered as a result of viral transformation and which may be involved in cell tumorigenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347979"}
{"pmid": "4347982", "title": "Lung uptake of  99m Tc-sulfur colloid.", "content": "Lung uptake of  99m Tc-sulfur colloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347982"}
{"pmid": "4347983", "title": "Interpretation of the  67 Ga photoscan.", "content": "Interpretation of the  67 Ga photoscan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347983"}
{"pmid": "4347981", "title": "Periodic variation in A-V conduction time: the 'supernormal' phase of A-V conduction. A study in differential dual A-V pathway conductivity and refractoriness.", "content": "Periodic variation in A-V conduction time: the 'supernormal' phase of A-V conduction. A study in differential dual A-V pathway conductivity and refractoriness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347981"}
{"pmid": "4347980", "title": "Axonal agranular reticulum and synaptic vesicles in cultured embryonic chick sympathetic neurons.", "content": "Axonal agranular reticulum and synaptic vesicles in cultured embryonic chick sympathetic neurons. Cultured chick embryonic sympathetic neurons contain an extensive axonal network of sacs and tubules of agranular reticulum. The reticulum is also seen branching into networks in axon terminals and varicosities. The axonal reticulum and perikaryal endoplasmic reticulum resemble one another in their content of cytochemically demonstrable enzyme activities (G6Pase and IDPase) and in their characteristic membrane thicknesses (narrower than plasma membrane or some Golgi membranes). From the reticulum, both along the axon and at terminals, there appear to form dense-cored vesicles ranging in size from 400 to 1,000 A in diameter. These vesicles behave pharmacologically and cytochemically like the classes of large and small catecholamine storage vesicles found in several adrenergic systems; for example, they can accumulate exogenous 5-hydroxydopamine. In addition, dense-cored vesicles at the larger (1,000 A) end of the size spectrum appear to arise within perikaryal membrane systems associated with the Golgi apparatus; this is true also of very large (800-3,500 A) dense-cored vesicles found in some perikarya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347980"}
{"pmid": "4347984", "title": "Apomorphine antagonism of the elevation of homovanillic acid induced by antipsychotic drugs.", "content": "Apomorphine antagonism of the elevation of homovanillic acid induced by antipsychotic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347984"}
{"pmid": "4347985", "title": "Effects of angiotensin II on cyclic 3'5'AMP in rat uterus.", "content": "Effects of angiotensin II on cyclic 3'5'AMP in rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347985"}
{"pmid": "4347986", "title": "Effect of cholecystokinin on the level of cyclic AMP and on mechanical activity in the isolated sphincter of Oddi.", "content": "Effect of cholecystokinin on the level of cyclic AMP and on mechanical activity in the isolated sphincter of Oddi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347986"}
{"pmid": "4347987", "title": "Spontaneous transmitter release and ACh sensitivity during glutaraldehyde fixation of rat diaphragm.", "content": "Spontaneous transmitter release and ACh sensitivity during glutaraldehyde fixation of rat diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347987"}
{"pmid": "4347989", "title": "A functional connection between postganglionic neurons in a bullfrog sympathetic ganglion.", "content": "A functional connection between postganglionic neurons in a bullfrog sympathetic ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347989"}
{"pmid": "4347988", "title": "Adenyl cyclase-phosphodiesterase system in arterial smooth muscle.", "content": "Adenyl cyclase-phosphodiesterase system in arterial smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347988"}
{"pmid": "4347990", "title": "Evidence for sodium dependent outward transport of the  3 H-norepinephrine mobilized by calcium at the adrenergic synapse. Inhibition of transport by desipramine.", "content": "Evidence for sodium dependent outward transport of the  3 H-norepinephrine mobilized by calcium at the adrenergic synapse. Inhibition of transport by desipramine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347990"}
{"pmid": "4347991", "title": "The mechanism of the drinking response to some hypotensive drugs: activation of the renin-angiotensin system by direct or reflex-mediated stimulation of  -receptors.", "content": "The mechanism of the drinking response to some hypotensive drugs: activation of the renin-angiotensin system by direct or reflex-mediated stimulation of  -receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347991"}
{"pmid": "4347993", "title": "Two morphologically distinct blood-brain barriers preventing entry of cytochrome c into cerebrospinal fluid.", "content": "Two morphologically distinct blood-brain barriers preventing entry of cytochrome c into cerebrospinal fluid. After intravenous injection, cytochrome c does not enter the cerebrospinal fluid. In most areas of the brain, the marker is prevented from leaving cerebral vessels by the capillary endothelium. In the choroid plexus, the marker passes freely out of capillaries into the extracellular space. However, it does not traverse tight junctions between epithelial cells and is rapidly incorporated into mnembrane-bound vesicles within the cell cytoplasm. Thereafter, cytochrome c is apparently removed by lysosomal degradation. These data suggest that there are at least two morphologically distinct blood-brain barriers to cytochrome c and that pinocytosis may be a mechanism for intracellular degradation rather than transcellular transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347993"}
{"pmid": "4347992", "title": "Effects of colchicine and cytochalasin B on the release of  3 H-norepinephrine from guinea-pig atria evoked by high potassium, nicotine and tyramine.", "content": "Effects of colchicine and cytochalasin B on the release of  3 H-norepinephrine from guinea-pig atria evoked by high potassium, nicotine and tyramine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347992"}
{"pmid": "4347994", "title": "Immunologic manipulation of metastases due to herpesvirus transformed cells.", "content": "Immunologic manipulation of metastases due to herpesvirus transformed cells. Herpes simplex virus type 1 (HSV-1), type 2 (HSV-2), and simian virus 40 (SV40) fail to induce immunity in weanling Syrian hamsters to transplant of hamster cells transformed by HSV-2. However, the development of metastatic tumors is markedly enhanced by prior immunization with HSV-1. Immunization with SV40, ultraviolet-irradiated tumor cells, or ultraviolet-irradiated normal hamster embryo cells inhibits the development of metastases. The HSV-hamster system appears a good one for the study of development, prevention, and control of metastases by mammalian cells transformed by a common human virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347994"}
{"pmid": "4347997", "title": "Development of tone-burst responses along the auditory pathway in the cat.", "content": "Development of tone-burst responses along the auditory pathway in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347997"}
{"pmid": "4347998", "title": "Neonatal hypoglycaemia due to an islet-cell adenoma.", "content": "Neonatal hypoglycaemia due to an islet-cell adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4347998"}
{"pmid": "4348000", "title": "Immunosuppression during pregnancy: transmission of azathioprine and its metabolites from the mother to the fetus.", "content": "Immunosuppression during pregnancy: transmission of azathioprine and its metabolites from the mother to the fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348000"}
{"pmid": "4348001", "title": "Passage of polymyxins from serum into milk in ewes.", "content": "Passage of polymyxins from serum into milk in ewes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348001"}
{"pmid": "4348002", "title": "Failure of either corticosteroids or ACTH to increase the leukocyte concentration in milk.", "content": "Failure of either corticosteroids or ACTH to increase the leukocyte concentration in milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348002"}
{"pmid": "4348003", "title": "Clinical course and histopathologic features of pseudorabies virus-induced keratoconjunctivitis in pigs.", "content": "Clinical course and histopathologic features of pseudorabies virus-induced keratoconjunctivitis in pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348003"}
{"pmid": "4348004", "title": "Oncogenic activity of feline fibrosarcoma virus in newborn pigs.", "content": "Oncogenic activity of feline fibrosarcoma virus in newborn pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348004"}
{"pmid": "4348007", "title": "Generation of phenoxy radicals by methemoglobin-hydrogen peroxide studies by electron paramagnetic resonance.", "content": "Generation of phenoxy radicals by methemoglobin-hydrogen peroxide studies by electron paramagnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348007"}
{"pmid": "4348006", "title": "Cyclic AMP phosphodiesterase activity at the external surface of intact skeletal muscles and stimulation of the enzyme by insulin.", "content": "Cyclic AMP phosphodiesterase activity at the external surface of intact skeletal muscles and stimulation of the enzyme by insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348006"}
{"pmid": "4348008", "title": "The effects of local anesthetics on lipid multilayers. A spin probe study.", "content": "The effects of local anesthetics on lipid multilayers. A spin probe study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348008"}
{"pmid": "4348010", "title": "The hydrolysis of triphosphoinositide by a phosphodiesterase in rat kidney cortex.", "content": "The hydrolysis of triphosphoinositide by a phosphodiesterase in rat kidney cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348010"}
{"pmid": "4348011", "title": "A membrane-bound alkaline inorganic pyrophosphatase in isolated spinach chloroplasts.", "content": "A membrane-bound alkaline inorganic pyrophosphatase in isolated spinach chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348011"}
{"pmid": "4348009", "title": "Collagen proline hydroxylase activity in the uterus of the rat during rapid collagen synthesis in vivo.", "content": "Collagen proline hydroxylase activity in the uterus of the rat during rapid collagen synthesis in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348009"}
{"pmid": "4348012", "title": "Deuterium isotope effects in the oxidation of alcohols in vitro and in vivo.", "content": "Deuterium isotope effects in the oxidation of alcohols in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348012"}
{"pmid": "4348005", "title": "Estimation of plasma renin activity by radioimmunoassay of angiotensin I.", "content": "Estimation of plasma renin activity by radioimmunoassay of angiotensin I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348005"}
{"pmid": "4348013", "title": "Diphosphopyridine nucleotide-linked D-lactate dehydrogenases from the horseshoe crab, Limulus polyphemus and the seaworm, Nereis virens. I. Physical and chemical properties.", "content": "Diphosphopyridine nucleotide-linked D-lactate dehydrogenases from the horseshoe crab, Limulus polyphemus and the seaworm, Nereis virens. I. Physical and chemical properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348013"}
{"pmid": "4348016", "title": "Protein synthesis in chicken muscular dystrophy.", "content": "Protein synthesis in chicken muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348016"}
{"pmid": "4348015", "title": "Interaction of pyruvate with pyruvate carboxylase and pyruvate kinase as studied by paramagnetic effects on  13 C relaxation rates.", "content": "Interaction of pyruvate with pyruvate carboxylase and pyruvate kinase as studied by paramagnetic effects on  13 C relaxation rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348015"}
{"pmid": "4348014", "title": "Diphosphopyridine nucleotide-linked D-lactate dehydrogenases from the horseshoe crab, Limulus polyphemus, and the seaworm, Nereis virens. II. Catalytic properties.", "content": "Diphosphopyridine nucleotide-linked D-lactate dehydrogenases from the horseshoe crab, Limulus polyphemus, and the seaworm, Nereis virens. II. Catalytic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348014"}
{"pmid": "4348018", "title": "Measurement of the water exchange rate of bound water in the manganese(II)-adenosine triphosphate complex by oxygen-17 nuclear magnetic resonance.", "content": "Measurement of the water exchange rate of bound water in the manganese(II)-adenosine triphosphate complex by oxygen-17 nuclear magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348018"}
{"pmid": "4348017", "title": "A stimulation by phosphate of malate transport and oxidation in rat adrenal mitochondria.", "content": "A stimulation by phosphate of malate transport and oxidation in rat adrenal mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348017"}
{"pmid": "4348019", "title": "The effect of maternal hypoxia on fetal pituitary hormone release in the sheep.", "content": "The effect of maternal hypoxia on fetal pituitary hormone release in the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348019"}
{"pmid": "4348020", "title": "Biochemical properties of human fetal mitochondria.", "content": "Biochemical properties of human fetal mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348020"}
{"pmid": "4348021", "title": "Usefulness of solid medium in Myjak's application (3) for current laboratory diagnostics of amoebiasis.", "content": "Usefulness of solid medium in Myjak's application (3) for current laboratory diagnostics of amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348021"}
{"pmid": "4348022", "title": "Effects of morphine on the Golgi apparatus and mitochondria of mammalian neurones.", "content": "Effects of morphine on the Golgi apparatus and mitochondria of mammalian neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348022"}
{"pmid": "4348023", "title": "Chromosome and chromatid exchanges in Chinese hamster cells.", "content": "Chromosome and chromatid exchanges in Chinese hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348023"}
{"pmid": "4348026", "title": "Bronchogenic carcinoma: the true story.", "content": "Bronchogenic carcinoma: the true story.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348026"}
{"pmid": "4348027", "title": "Nobel Prize winner talks about noradrenaline, nerves and aging.", "content": "Nobel Prize winner talks about noradrenaline, nerves and aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348027"}
{"pmid": "4348033", "title": "Reticulum cell sarcoma and malignant histiocytoma of the soft tissues.", "content": "Reticulum cell sarcoma and malignant histiocytoma of the soft tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348033"}
{"pmid": "4348034", "title": "Sequential studies on spontaneous mammary and hepatocarcinogenesis in reciprocal crosses of ICRC and C3H (Jax) strains.", "content": "Sequential studies on spontaneous mammary and hepatocarcinogenesis in reciprocal crosses of ICRC and C3H (Jax) strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348034"}
{"pmid": "4348035", "title": "Mapping of sites on the surface membrane of mammalian cells. II. Relationship of sites for concanavalin A and an ornithine, leucine copolymer.", "content": "Mapping of sites on the surface membrane of mammalian cells. II. Relationship of sites for concanavalin A and an ornithine, leucine copolymer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348035"}
{"pmid": "4348036", "title": "Neuropathy of metachromatic leucodystrophy.", "content": "Neuropathy of metachromatic leucodystrophy. We describe two patients with metachromatic leucodystrophy who presented with peripheral neuropathy and had no evidence of central nervous system involvement at the time of presentation. Such an occurrence is not well recognized and the diagnosis is usually missed until the other features of the disease manifest themselves. Early recognition of this disease may become of practical importance from the point of view of therapy, judging from recent developments, and is also important from the point of view of genetic counselling. We suggest that cases of peripheral neuropathy in infancy and childhood, should be subjected to peripheral nerve biopsy when the aetiology is not obvious.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348036"}
{"pmid": "4348037", "title": "Differential sensitivity of motor and sensory fibres in human ulnar nerve.", "content": "Differential sensitivity of motor and sensory fibres in human ulnar nerve. The human ulnar nerve has been stimulated with square-wave pulses of various fixed durations. Measurements were made of the growth of hand myograms compared with elbow neurograms and of hand myograms compared with finger neurograms, for fixed durations of pulses and increasing strength. The effect of blocking sensory action potentials with stimuli of various durations has been investigated, as well as the blocking of action potentials in motor nerve fibres by voluntary activity. It is concluded that pulses of long duration (1 msec or more) selectively stimulate sensory fibres at threshold, whereas short duration pulses (less than 200 μsec) selectively stimulate motor fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348037"}
{"pmid": "4348038", "title": "Effect of procaine infiltration into biceps brachii muscle in man on supraspinal control of reflex transmission.", "content": "Effect of procaine infiltration into biceps brachii muscle in man on supraspinal control of reflex transmission. Sensitivity of the tonic stretch reflex (TSR) of biceps brachii in normal man was measured at different levels of voluntary contraction before and after gamma efferent nerve fibres were selectively blocked by infiltration of dilute procaine. The procaine infiltration reduced TSR sensitivity to one half of its control value. It had no effect, however, on the slope of the relation between TSR gain and level of voluntary contraction. It was concluded that the increase in TSR sensitivity associated with voluntary contraction was not mediated by the gamma efferent fibres and control of reflex transmission is therefore not the main function of the fusimotor system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348038"}
{"pmid": "4348041", "title": "Metabolic neuropathy.", "content": "Metabolic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348041"}
{"pmid": "4348043", "title": "Cytotoxic effect of viruses on Harding-Passey melanoma in tissue culture.", "content": "Cytotoxic effect of viruses on Harding-Passey melanoma in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348043"}
{"pmid": "4348032", "title": "Calcium, cyclic adenosine 3',5'-monophosphate, and the control of cell proliferation: a review.", "content": "Calcium, cyclic adenosine 3',5'-monophosphate, and the control of cell proliferation: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348032"}
{"pmid": "4348044", "title": "Induction of virus synthesis in polyoma-transformed BHK-21 cells.", "content": "Induction of virus synthesis in polyoma-transformed BHK-21 cells. BHK-21 cells were transformed with polyoma virus mutants Ts-a and Ts-25 by using a temperature shift from 31 to 39 C at 5 days after infection so that rescuable transformants could be isolated. Clones which yielded virus after fusion with mouse cells were scored and maintained at 39 C in the presence of antipolyoma virus antiserum. Generally, no infectious viral deoxyribonucleic acid (DNA) could be found in Hirt supernatant fractions of these lines when maintained at 39 C, but DNA-DNA reannealing measurements detected two to six viral genomes per diploid cell genome in the nuclear DNA. Fusion with permissive cells was not necessary to induce the synthesis of infectious virus; cell lines shifted to 31 C produce the equivalent of 100 viral genomes per cell after 5 days. In some cell lines up to 1% of the cells formed infectious centers upon a shift to 31 C, and 100% of the subclones of a line were inducible. Growth at 31 C selected for a noninducible population which was still transformed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348044"}
{"pmid": "4348045", "title": "The influence of rare earths on hepatic gluconeogenesis.", "content": "The influence of rare earths on hepatic gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348045"}
{"pmid": "4348042", "title": "Oxaluria.", "content": "Oxaluria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348042"}
{"pmid": "4348047", "title": "Effect of dibutyryl cyclic-AMP on levels of dopamine- -hydroxylase in isolated superior cervical ganglia.", "content": "Effect of dibutyryl cyclic-AMP on levels of dopamine- -hydroxylase in isolated superior cervical ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348047"}
{"pmid": "4348046", "title": "Actions of various cyclic nucleotides, nucleosides and purine bases on the synthesis of corticosterone in vitro.", "content": "Actions of various cyclic nucleotides, nucleosides and purine bases on the synthesis of corticosterone in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348046"}
{"pmid": "4348048", "title": "Erythropoiesis in the yolk sac of the early chick embryo: an electron microscope and microspectrophotometric study.", "content": "Erythropoiesis in the yolk sac of the early chick embryo: an electron microscope and microspectrophotometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348048"}
{"pmid": "4348049", "title": "Light-induced changes in the ultrastructure of a plasmodial myxomycete.", "content": "Light-induced changes in the ultrastructure of a plasmodial myxomycete.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348049"}
{"pmid": "4348050", "title": "Freeze-fractured lamellar body membranes of the rat lung great alveolar cell.", "content": "Freeze-fractured lamellar body membranes of the rat lung great alveolar cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348050"}
{"pmid": "4348051", "title": "Ultrastructural changes in the nuclear envelope of larval fat body cells of Simulium vittatum (Diptera) induced by microsporidian infection of Thelohania bracteata.", "content": "Ultrastructural changes in the nuclear envelope of larval fat body cells of Simulium vittatum (Diptera) induced by microsporidian infection of Thelohania bracteata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348051"}
{"pmid": "4348052", "title": "Histology and ultrastructure of the tube foot epithelium in the phanerozonian starfish, Astropecten.", "content": "Histology and ultrastructure of the tube foot epithelium in the phanerozonian starfish, Astropecten.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348052"}
{"pmid": "4348053", "title": "Cytodifferentiation of maturing pine tracheids: the final stage.", "content": "Cytodifferentiation of maturing pine tracheids: the final stage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348053"}
{"pmid": "4348054", "title": "The ultrastructure and function of pericardial cells and other nephrocytes in an insect: Calliphora erythrocephala.", "content": "The ultrastructure and function of pericardial cells and other nephrocytes in an insect: Calliphora erythrocephala.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348054"}
{"pmid": "4348056", "title": "Fibrous xanthomas and xanthosarcomas of the meninges and the brain.", "content": "Fibrous xanthomas and xanthosarcomas of the meninges and the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348056"}
{"pmid": "4348057", "title": "Hemorrhage from cecal ulcers of cytomegalovirus infection: report of a case.", "content": "Hemorrhage from cecal ulcers of cytomegalovirus infection: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348057"}
{"pmid": "4348058", "title": "Oncogenic viruses.", "content": "Oncogenic viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348058"}
{"pmid": "4348060", "title": "Susceptibility of chick brain L-glutamic acid decarboxylase and other neurotransmitter enzymes to hyperbaric oxygen in vitro.", "content": "Susceptibility of chick brain L-glutamic acid decarboxylase and other neurotransmitter enzymes to hyperbaric oxygen in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348060"}
{"pmid": "4348061", "title": "Testosterone-stimulation of adenyl cyclase and cyclic 3',5'-adnosine monophosphate- 3 H formation in rat seminal vesicles.", "content": "Testosterone-stimulation of adenyl cyclase and cyclic 3',5'-adnosine monophosphate- 3 H formation in rat seminal vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348061"}
{"pmid": "4348062", "title": "Effects of clofibrate, in vitro, on mitochondrial respiration and oxidative phosphorylation.", "content": "Effects of clofibrate, in vitro, on mitochondrial respiration and oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348062"}
{"pmid": "4348064", "title": "Haem protein P-450 from the adrenal cortex: interaction with steroids and the hydroxylation reaction.", "content": "Haem protein P-450 from the adrenal cortex: interaction with steroids and the hydroxylation reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348064"}
{"pmid": "4348063", "title": "Structure and reactions of oxygenase active centers: cytochrome P-450 and iron sulfur proteins.", "content": "Structure and reactions of oxygenase active centers: cytochrome P-450 and iron sulfur proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348063"}
{"pmid": "4348065", "title": "Cholesterol hydroxylation in the adrenal cortex and liver.", "content": "Cholesterol hydroxylation in the adrenal cortex and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348065"}
{"pmid": "4348066", "title": "A study of transfer RNA methylation.", "content": "A study of transfer RNA methylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348066"}
{"pmid": "4348067", "title": "Hydroxylamine-dependent reactions catalyzed by a lysyl-tRNA synthetase of Escherichia coli B.", "content": "Hydroxylamine-dependent reactions catalyzed by a lysyl-tRNA synthetase of Escherichia coli B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348067"}
{"pmid": "4348068", "title": "Kinetics of synthesis of cytochromes   and   3  during respiratory adaptation of yeast.", "content": "Kinetics of synthesis of cytochromes   and   3  during respiratory adaptation of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348068"}
{"pmid": "4348069", "title": "Purification of superoxide dismutase from fungi and characterization of the reaction of the enzyme with catechols by electron spin resonance spectroscopy.", "content": "Purification of superoxide dismutase from fungi and characterization of the reaction of the enzyme with catechols by electron spin resonance spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348069"}
{"pmid": "4348070", "title": "Cyclic AMP-induced differentiated mouse neuroblastoma cells lose tumourgenic characteristics.", "content": "Cyclic AMP-induced differentiated mouse neuroblastoma cells lose tumourgenic characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348070"}
{"pmid": "4348059", "title": "Ultrastructure of lipid bodies and lysosomes in the skin in Fabry's disease (angiokeratoma corporis diffusum).", "content": "Ultrastructure of lipid bodies and lysosomes in the skin in Fabry's disease (angiokeratoma corporis diffusum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348059"}
{"pmid": "4348073", "title": "Alkaline and acid phosphatase in the intestines of rats infected with a virulent strain of Entamoeba histolytica and treated with emetine and Flagyl.", "content": "Alkaline and acid phosphatase in the intestines of rats infected with a virulent strain of Entamoeba histolytica and treated with emetine and Flagyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348073"}
{"pmid": "4348074", "title": "Microspectrophotometric analysis of malarial pigment.", "content": "Microspectrophotometric analysis of malarial pigment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348074"}
{"pmid": "4348075", "title": "Schistosoma mansoni: histochemical analysis of the postacetabular gland secretion of cercariae.", "content": "Schistosoma mansoni: histochemical analysis of the postacetabular gland secretion of cercariae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348075"}
{"pmid": "4348076", "title": "Transient increase in capillary permeability induced by Clostridium perfringens type A enterotoxin.", "content": "Transient increase in capillary permeability induced by Clostridium perfringens type A enterotoxin. A transient increase in capillary permeability was induced in the skin of guinea pigs by Clostridium perfringens type A enterotoxin. Maximum intensity and maximum diameter of the area of increased capillary permeability were obtained with injection of enterotoxin 10 to 20 min before dye injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348076"}
{"pmid": "4348077", "title": "Foot-and-mouth disease virus: selection by homogenized calf kidney adsorption and cell culture passage.", "content": "Foot-and-mouth disease virus: selection by homogenized calf kidney adsorption and cell culture passage. Foot-and-mouth disease virus was passaged 20 times by alternately adsorbing the virus with homogenized calf kidney and propagating the adsorption-resistant fraction of virus in cell cultures. Passage of the virus was accompanied by a marked decrease in pathogenicity for 35-day-old mice and a reduction in its ability to adsorb to homogenized kidney from such mice. Adsorption by homogenized calf kidney and infant mouse kidney also decreased with passage, but pathogenicity for cattle and infant mice remained high. The passaged virus did not seem to change antigenically. When the 20th-passage virus was serially passaged 10 times in cell cultures, no reversion in pathogenicity for 35-day-old mice was observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348077"}
{"pmid": "4348079", "title": "Saccadic inhibition induced by brain-stem stimulation in the alert monkey.", "content": "Saccadic inhibition induced by brain-stem stimulation in the alert monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348079"}
{"pmid": "4348080", "title": "Conformational changes in membranous preparations of cytochrome oxidase.", "content": "Conformational changes in membranous preparations of cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348080"}
{"pmid": "4348078", "title": "Isolation and characterization of Mycoplasma conjunctivae sp. n. from sheep and goats with keratoconjunctivitis.", "content": "Isolation and characterization of Mycoplasma conjunctivae sp. n. from sheep and goats with keratoconjunctivitis. Fourteen conjunctival strains of mycoplasma were isolated from infected sheep and goats in two separate naturally occurring outbreaks of keratoconjunctivitis (pink-eye). The biological and serological properties and cell protein patterns of these strains are presented in this report. These strains were related to each other and were unrelated to 40 recognized Mycoplasma and Acholeplasma species and serotypes. We are proposing that this group of mycoplasmas be named M. conjunctivae. The role of M. conjunctivae in the etiology of keratoconjunctivitis in sheep and goats remains to be determined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348078"}
{"pmid": "4348081", "title": "Proteins of cytochrome oxidase in fractions prepared with deoxycholate from bovine heart submitochondrial particles.", "content": "Proteins of cytochrome oxidase in fractions prepared with deoxycholate from bovine heart submitochondrial particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348081"}
{"pmid": "4348082", "title": "Variability of the K+-Na+ discrimination of beauvericin in mitochondrial membranes.", "content": "Variability of the K+-Na+ discrimination of beauvericin in mitochondrial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348082"}
{"pmid": "4348086", "title": "In vitro transformation assay of major fractions of cigarette smoke condensate (CSC) in mammalian cell lines.", "content": "In vitro transformation assay of major fractions of cigarette smoke condensate (CSC) in mammalian cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348086"}
{"pmid": "4348087", "title": "Changes in rat liver plasma membrane phospholipids during aging.", "content": "Changes in rat liver plasma membrane phospholipids during aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348087"}
{"pmid": "4348088", "title": "The effect of chloroquine on herpesvirus infection in vitro and in vivo.", "content": "The effect of chloroquine on herpesvirus infection in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348088"}
{"pmid": "4348089", "title": "The nature of collagen in the carrageenin granuloma.", "content": "The nature of collagen in the carrageenin granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348089"}
{"pmid": "4348090", "title": "Effect of cyclophosphamide on the genetic resistance of C 3 H mice to mouse hepatitis virus.", "content": "Effect of cyclophosphamide on the genetic resistance of C 3 H mice to mouse hepatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348090"}
{"pmid": "4348091", "title": "The effects of prostaglandin E 1  on erythropoietin production.", "content": "The effects of prostaglandin E 1  on erythropoietin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348091"}
{"pmid": "4348092", "title": "Effect of angiotensin II on uptake and release of dl- 3 H-metaraminol.", "content": "Effect of angiotensin II on uptake and release of dl- 3 H-metaraminol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348092"}
{"pmid": "4348093", "title": "Regulation of the in vitro synthesis of angiotensin I.", "content": "Regulation of the in vitro synthesis of angiotensin I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348093"}
{"pmid": "4348085", "title": "Cation activated hydrolysis of ATP by the soluble fraction of Bacillus brevis.", "content": "Cation activated hydrolysis of ATP by the soluble fraction of Bacillus brevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348085"}
{"pmid": "4348094", "title": "Reaction of endogenous renin with exogenous renin substrate within the isolate perfused rat kidney.", "content": "Reaction of endogenous renin with exogenous renin substrate within the isolate perfused rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348094"}
{"pmid": "4348095", "title": "Possible mechanisms of impaired interferon production in stressed mice.", "content": "Possible mechanisms of impaired interferon production in stressed mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348095"}
{"pmid": "4348096", "title": "An in vivo corticotropin-releasing factor (CRF) assay based on plasma levels of radioimmunoassayable ACTH.", "content": "An in vivo corticotropin-releasing factor (CRF) assay based on plasma levels of radioimmunoassayable ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348096"}
{"pmid": "4348097", "title": "Testosterone-induced depression of adrenergic activity in the perfused canin hindlimb.", "content": "Testosterone-induced depression of adrenergic activity in the perfused canin hindlimb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348097"}
{"pmid": "4348098", "title": "Extracellular localization of lysozyme in rachitic rat cartilage.", "content": "Extracellular localization of lysozyme in rachitic rat cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348098"}
{"pmid": "4348099", "title": "Pyruvate dehydrogenase, the citrate condensing enzyme and the utilization of  14 C-labeled lactate, pyruvate and alanine by slices of lactating mammary gland and adenocarcinoma of mouse mammary gland.", "content": "Pyruvate dehydrogenase, the citrate condensing enzyme and the utilization of  14 C-labeled lactate, pyruvate and alanine by slices of lactating mammary gland and adenocarcinoma of mouse mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348099"}
{"pmid": "4348100", "title": "Infection-mediated resistance to cell fusion by inactive Sendai virus.", "content": "Infection-mediated resistance to cell fusion by inactive Sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348100"}
{"pmid": "4348101", "title": "Sensitivity of human conjunctival tissue cultures to adenovirus 8, herpes simplex and vaccinia viruses. Induction of resistance by an interferon inducer.", "content": "Sensitivity of human conjunctival tissue cultures to adenovirus 8, herpes simplex and vaccinia viruses. Induction of resistance by an interferon inducer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348101"}
{"pmid": "4348107", "title": "Ultrastructural modifications of frog urinary bladder epithelium under the influence of hypertonic media.", "content": "Ultrastructural modifications of frog urinary bladder epithelium under the influence of hypertonic media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348107"}
{"pmid": "4348109", "title": "Angiography in the diagnosis and management of extrapancreatic islet-cell tumors.", "content": "Angiography in the diagnosis and management of extrapancreatic islet-cell tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348109"}
{"pmid": "4348110", "title": "Histologic patterns of secondary syphilis.", "content": "Histologic patterns of secondary syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348110"}
{"pmid": "4348111", "title": "Recurrent skin cancer.", "content": "Recurrent skin cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348111"}
{"pmid": "4348113", "title": "Lateral geniculate spikes and eye movements in sleeping and awake cats following uni- and bilateral labyrinthectomy and cerebellar lesion.", "content": "Lateral geniculate spikes and eye movements in sleeping and awake cats following uni- and bilateral labyrinthectomy and cerebellar lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348113"}
{"pmid": "4348114", "title": "Studies on kinin-like substances in brain.", "content": "Studies on kinin-like substances in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348114"}
{"pmid": "4348115", "title": "Inhibitory effects of chlorpromazine and diethylaminoethyl diphenylvalerate (SKF 525-A) on alanine incorporation into protein and  -aminoisobutyric acid uptake in rat hepatoma cells in culture.", "content": "Inhibitory effects of chlorpromazine and diethylaminoethyl diphenylvalerate (SKF 525-A) on alanine incorporation into protein and  -aminoisobutyric acid uptake in rat hepatoma cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348115"}
{"pmid": "4348116", "title": "Effects of sodium salicylate and acetylsalicylic acid on the lipolytic system of fat cells.", "content": "Effects of sodium salicylate and acetylsalicylic acid on the lipolytic system of fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348116"}
{"pmid": "4348117", "title": "Antiparasitic nitroimidazoles. IV. Serum protein binding and mode of action of 2-(4'-carboxystyryl)-5-nitro-1-vinylimidazole.", "content": "Antiparasitic nitroimidazoles. IV. Serum protein binding and mode of action of 2-(4'-carboxystyryl)-5-nitro-1-vinylimidazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348117"}
{"pmid": "4348118", "title": "Effect of rifampicin on mitochondrial protein synthesis in rat liver.", "content": "Effect of rifampicin on mitochondrial protein synthesis in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348118"}
{"pmid": "4348112", "title": "Epstein-Barr virus antibody levels in systemic lupus erythematosus.", "content": "Epstein-Barr virus antibody levels in systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348112"}
{"pmid": "4348120", "title": "Effect of   9 - and   8 -tetrahydrocannabinol on the peripheral autonomic nervous system in vitro.", "content": "Effect of   9 - and   8 -tetrahydrocannabinol on the peripheral autonomic nervous system in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348120"}
{"pmid": "4348121", "title": "The inhibition of sympathetic preganglionic neurons by somatic afferents.", "content": "The inhibition of sympathetic preganglionic neurons by somatic afferents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348121"}
{"pmid": "4348122", "title": "Vitamin A status and hepatic drug metabolism in the rat.", "content": "Vitamin A status and hepatic drug metabolism in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348122"}
{"pmid": "4348123", "title": "Hyperlipoproteinemia. Prevalence in a free-living population in Albany, New York.", "content": "Hyperlipoproteinemia. Prevalence in a free-living population in Albany, New York.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348123"}
{"pmid": "4348124", "title": "Properties of the elongation factors from Escherichia coli. Exchange of elongation factor G during elongation of polypeptide chain.", "content": "Properties of the elongation factors from Escherichia coli. Exchange of elongation factor G during elongation of polypeptide chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348124"}
{"pmid": "4348125", "title": "Purification of a phosphodiesterase from Bothrops atrox venom by affinity chromatography.", "content": "Purification of a phosphodiesterase from Bothrops atrox venom by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348125"}
{"pmid": "4348127", "title": "Cytochrome c: a thermodynamic study of relationships among oxidation state, ion-binding and structural parameters. 2. Ion-binding linked to oxidation state.", "content": "Cytochrome c: a thermodynamic study of relationships among oxidation state, ion-binding and structural parameters. 2. Ion-binding linked to oxidation state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348127"}
{"pmid": "4348126", "title": "Cytochrome c: a thermodynamic study of the relationships among oxidation state, ion-binding and structural parameters. 1. The effects of temperature, pH and electrostatic media on the standard redox potential of cytochrome c.", "content": "Cytochrome c: a thermodynamic study of the relationships among oxidation state, ion-binding and structural parameters. 1. The effects of temperature, pH and electrostatic media on the standard redox potential of cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348126"}
{"pmid": "4348128", "title": "Metabolic regulation of steroidogenesis in adrenocortical carcinoma cells of rat. Effect of adrenocorticotropin and adenosine cyclic 3':5'-monophosphate on corticosteroidogenesis.", "content": "Metabolic regulation of steroidogenesis in adrenocortical carcinoma cells of rat. Effect of adrenocorticotropin and adenosine cyclic 3':5'-monophosphate on corticosteroidogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348128"}
{"pmid": "4348130", "title": "Pleuro-pulmonary complications of amoebiasis.", "content": "Pleuro-pulmonary complications of amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348130"}
{"pmid": "4348131", "title": "Hepato-pulmonary amoebiasis.", "content": "Hepato-pulmonary amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348131"}
{"pmid": "4348132", "title": "The effect of topical corticosteroids on the susceptibility of immune animals to reinoculation with Herpes simplex.", "content": "The effect of topical corticosteroids on the susceptibility of immune animals to reinoculation with Herpes simplex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348132"}
{"pmid": "4348133", "title": "A modified method for the isolation of melanosomes from B16 melanoma.", "content": "A modified method for the isolation of melanosomes from B16 melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348133"}
{"pmid": "4348134", "title": "'Collagenase-like peptidase in human, rat and bull spermatozoa.", "content": "'Collagenase-like peptidase in human, rat and bull spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348134"}
{"pmid": "4348136", "title": "Relationship between ligand binding and conformational change of macromolecules in the two-state allosteric model.", "content": "Relationship between ligand binding and conformational change of macromolecules in the two-state allosteric model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348136"}
{"pmid": "4348135", "title": "A general-purpose electronic model for arbitrary configurations of neurons.", "content": "A general-purpose electronic model for arbitrary configurations of neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348135"}
{"pmid": "4348137", "title": "Theoretical implications of the size principle of motoneurone recruitment.", "content": "Theoretical implications of the size principle of motoneurone recruitment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348137"}
{"pmid": "4348138", "title": "Association of two contiguous urological tumors with adult Wilms tumor.", "content": "Association of two contiguous urological tumors with adult Wilms tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348138"}
{"pmid": "4348139", "title": "Intraductal carcinoma of the prostate gland.", "content": "Intraductal carcinoma of the prostate gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348139"}
{"pmid": "4348140", "title": "Wilms tumor: a clinical pathological correlation.", "content": "Wilms tumor: a clinical pathological correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348140"}
{"pmid": "4348141", "title": "Subcellular muscle studies in the prune belly syndrome.", "content": "Subcellular muscle studies in the prune belly syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348141"}
{"pmid": "4348144", "title": "The neuroleptics. 2. Neurophysiology and neuropharmacology.", "content": "The neuroleptics. 2. Neurophysiology and neuropharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348144"}
{"pmid": "4348145", "title": "Histological and molecular biochemistry.", "content": "Histological and molecular biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348145"}
{"pmid": "4348146", "title": "SV40 virus-specific RNA synthesis in transformed human cells.", "content": "SV40 virus-specific RNA synthesis in transformed human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348146"}
{"pmid": "4348147", "title": "Establishment of human malignant melanoma clonal cell lines that secrete ectopic adrenocorticotropin.", "content": "Establishment of human malignant melanoma clonal cell lines that secrete ectopic adrenocorticotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348147"}
{"pmid": "4348148", "title": "Physiotherapy in the treatment of leprosy.", "content": "Physiotherapy in the treatment of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348148"}
{"pmid": "4348149", "title": "Neuropathy in chronic renal disease.", "content": "Neuropathy in chronic renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348149"}
{"pmid": "4348150", "title": "Catecholamine-containing neurones and electrical self-stimulation. 1. A review of some data.", "content": "Catecholamine-containing neurones and electrical self-stimulation. 1. A review of some data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348150"}
{"pmid": "4348152", "title": "Membrane resistance changes underlying the bipolar cell response in the carp retina.", "content": "Membrane resistance changes underlying the bipolar cell response in the carp retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348152"}
{"pmid": "4348153", "title": "Bipolar-amacrine transmission in the carp retina.", "content": "Bipolar-amacrine transmission in the carp retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348153"}
{"pmid": "4348154", "title": "Viral hepatitis. Report of a WHO scientific group.", "content": "Viral hepatitis. Report of a WHO scientific group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348154"}
{"pmid": "4348157", "title": "Neutralization tests for foot-and-mouth disease, equine rhino-, porcine entero-, Aujeszky- and rhinopneumonitis viruses. Comparison of results obtained by a simple microculture plaque reduction test and various traditional tests.", "content": "Neutralization tests for foot-and-mouth disease, equine rhino-, porcine entero-, Aujeszky- and rhinopneumonitis viruses. Comparison of results obtained by a simple microculture plaque reduction test and various traditional tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348157"}
{"pmid": "4348158", "title": "Comparison of isometric exercise and angiotensin infusion as stress test for evaluation of left ventricular function.", "content": "Comparison of isometric exercise and angiotensin infusion as stress test for evaluation of left ventricular function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348158"}
{"pmid": "4348159", "title": "Coexistent congenital cytomegalovirus and toxoplasmosis in a stillborn.", "content": "Coexistent congenital cytomegalovirus and toxoplasmosis in a stillborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348159"}
{"pmid": "4348163", "title": "Attempts to produce tumors in mice with CELO virus.", "content": "Attempts to produce tumors in mice with CELO virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348163"}
{"pmid": "4348162", "title": "On the kinetics of poliovirus-specific protein and RNA synthesis in poliovirus-infected cells.", "content": "On the kinetics of poliovirus-specific protein and RNA synthesis in poliovirus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348162"}
{"pmid": "4348164", "title": "Electron microscopic study of Sindbis virus morphogenesis.", "content": "Electron microscopic study of Sindbis virus morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348164"}
{"pmid": "4348165", "title": "Isolation and characterization of reoviruses isolated from sheep.", "content": "Isolation and characterization of reoviruses isolated from sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348165"}
{"pmid": "4348160", "title": "Pain: a current view of neural mechanisms.", "content": "Pain: a current view of neural mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348160"}
{"pmid": "4348167", "title": "Mössbauer effect in rubredoxin. Determination of the hyperfine field of the iron in a simple iron-sulphur protein.", "content": "Mössbauer effect in rubredoxin. Determination of the hyperfine field of the iron in a simple iron-sulphur protein. 1. Rubredoxin isolated from the green photosynthetic bacterium Chloropseudomonas ethylica was similar in composition to those from anaerobic fermentative bacteria. Amino acid analysis indicated a minimum molecular weight of 6352 with one iron atom per molecule. 2. The circular-dichroism and electron-paramagnetic-resonance spectra of Ch. ethylica rubredoxin showed many similarities to those of Clostridium pasteurianum, but suggested that there may be subtle differences in the protein conformation about the iron atom. 3. Mössbauer-effect measurements on rubredoxin from Cl. pasteurianum and Ch. ethylica showed that in the oxidized state the iron (high-spin Fe(3+)) has a hyperfine field of 370+/-3kG, whereas in the reduced state (high-spin Fe(2+)) the hyperfine field tensor is anisotropic with a component perpendicular to the symmetry axis of the ion of about -200kG. For the reduced protein the sign of the electric-field gradient is negative, i.e. the ground state of the Fe(2+) is a [unk] orbital. There is a large non-cubic ligand-field splitting (Delta/k=900 degrees K), and a small spin-orbit splitting (D~+4.4cm(-1)) of the Fe(2+) levels. 4. The contributions of core polarization to the hyperfine field in the Fe(3+) and Fe(2+) ions are estimated to be -370 and -300kG respectively. 5. The significance of these results in interpretation of the Mössbauer spectra of other iron-sulphur proteins is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348167"}
{"pmid": "4348168", "title": "Purine ribonucleotide biosynthesis, interconversion and catabolism in mouse brain in vitro.", "content": "Purine ribonucleotide biosynthesis, interconversion and catabolism in mouse brain in vitro. The relative rates of the synthetic, interconversion and catabolic reactions of purine metabolism in chopped mouse cerebrum were studied. The rates of incorporation of [(14)C]adenine and [(14)C]hypoxanthine into purine ribonucleotides were much less than the potential activities of adenine phosphoribosyltransferase and hypoxanthine phosphoribosyltransferase, and the rates of incorporation were stimulated by the addition of guanosine to the incubation mixture. The availability of ribose phosphates may be a limiting factor for the formation of ribonucleotides from purine bases. The rate of incorporation of [(14)C]adenosine into purine ribonucleotides was at least seven- to eight-fold higher than that of adenine. The radioactivity in adenine ribonucleotides synthesized from adenine and hypoxanthine was about 100- and ten-fold respectively higher than that in the radioactive guanine ribonucleotides. The conversion of inosinate into guanine ribonucleotides was probably limited by the amount of inosinate available, and the conversion of adenine ribonucleotides into guanine ribonucleotides was probably limited by the activity of adenylate deaminase. The rate of catabolism of [(14)C]adenosine was low in comparison with its rate of utilization for ribonucleotide synthesis. A fraction of the [(14)C]hypoxanthine was catabolized to xanthine and urate. [(14)C]Guanine was completely converted into xanthine, mostly by the guanine deaminase that was released during incubation of chopped mouse cerebrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348168"}
{"pmid": "4348171", "title": "Release of creatine phosphokinase from muscle. II. Effect of multiple doses of polymyxin B or compound 48-80 on increases in plasma enzyme levels.", "content": "Release of creatine phosphokinase from muscle. II. Effect of multiple doses of polymyxin B or compound 48-80 on increases in plasma enzyme levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348171"}
{"pmid": "4348172", "title": "Influence of pH on human renin activity with different substrates: role of substrate denaturation.", "content": "Influence of pH on human renin activity with different substrates: role of substrate denaturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348172"}
{"pmid": "4348170", "title": "Histone phosphatase and cyclic nucleotide-stimulated protein kinase from human lymphocytes.", "content": "Histone phosphatase and cyclic nucleotide-stimulated protein kinase from human lymphocytes. 1. Extracts of human peripheral blood lymphocytes contained a histone phosphatase that catalysed the release of P(i) from phosphorylated whole thymus histone. 2. Stimulation of the phosphatase was obtained by concentrations of KCl and NaCl of up to 75mm, and by MgCl(2); CaCl(2) inhibited the enzymic activity. 3. In the absence of MgCl(2), phosphoenol-pyruvate inhibited histone phosphatase activity; this inhibition could be partially reversed by adding MgCl(2) to assays. 4. Lymphocyte extracts contained a protein kinase activity which was maximally stimulated by 1mum-cyclic AMP (adenosine 3':5'-cyclic monophosphate) or by 0.1mm-cyclic GMP (guanosine 3':5'-cyclic monophosphate). 5. Incubation of the enzyme with histone in the absence of ATP or MgCl(2) resulted in the dissociation of the enzyme into a lower-molecular-weight species that was not stimulated by cyclic AMP. This effect could be prevented if ATP and MgCl(2) were present in reaction mixtures before histone and enzyme were allowed to interact. 6. Cyclic AMP also dissociated the kinase into a lower-molecular-weight species. 7. In the presence of 1mum-AMP, half-maximal activities were obtained with 0.92mm-MgCl(2), 6.0mum-ATP and 0.23mg of whole thymus histone/ml.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348170"}
{"pmid": "4348169", "title": "Fractionation of nuclei from brain by zonal centrifugation and a study of the ribonucleic acid polymerase activity in the various classes of nuclei.", "content": "Fractionation of nuclei from brain by zonal centrifugation and a study of the ribonucleic acid polymerase activity in the various classes of nuclei. 1. The nuclei of the cells of the whole rat brain have been fractionated in a B-XIV zonal rotor with a discontinuous gradient of sucrose. Five fractions were obtained. Zone (I) contained neuronal nuclei (70%) and astrocytic nuclei (23%). Zone (II) contained astrocytic nuclei (81%) and neuronal nuclei (15%). Zone (III) contained astrocytic nuclei (84%) and oligodendrocytic nuclei (15%). Zone (IV) contained oligodendrocytic nuclei (92%) and zone (V) contained only oligodendrocytic nuclei. 2. The content of DNA, RNA and protein per nucleus was determined for each zone. Although the amount of DNA per nucleus is constant (7pg) the RNA varies from 4.5 to 2.5pg/nucleus and the protein from 38 to 17.6pg/nucleus. The neuronal nuclei have the greatest amounts of protein. The oligodendrocytic nuclei have the least content of RNA and protein. 3. The effects of pH, ionic strength, and Mg(2+) and Mn(2+) concentration on the activity of the nuclear system for synthesis in vitro of RNA have been investigated for unfractionated nuclei. From these studies a standard set of conditions for the assay of nuclear RNA polymerase has been established. 4. The activity of the RNA polymerase in each of the zonal fractions has been determined in the presence and in the absence of alpha-amanitin. Zone (II) is the most active, followed by zone (I). The nuclei of zones (IV) and (V) have comparable activity, which is 40% of that of zone (II). 5. The extent of incorporation of each of the four labelled nucleoside triphosphates by the nuclei from each zone has been measured. These values have been used to calculate the base composition of the RNA synthesized in vitro in each class of nucleus. 6. The effect of changes in the condition of assay of RNA polymerase in the different classes of nuclei has been investigated. Significant differences in the response to concentrations of metal ions and ammonium sulphate have been observed. 7. Homopolymer formation in each zone of brain nuclei has been determined. The extent of formation of the four homopolymers roughly parallels the RNA polymerase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348169"}
{"pmid": "4348173", "title": "Two forms of UDPglucose-4-epimerase from mammalian liver.", "content": "Two forms of UDPglucose-4-epimerase from mammalian liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348173"}
{"pmid": "4348174", "title": "Comparative specificity of prenyltransferase of pig liver and pumpkin with respect to artificial substrates.", "content": "Comparative specificity of prenyltransferase of pig liver and pumpkin with respect to artificial substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348174"}
{"pmid": "4348175", "title": "Partial prufication and properties of the cyclic AMP and the cyclic GMP phosphodiesterases of bovine liver.", "content": "Partial prufication and properties of the cyclic AMP and the cyclic GMP phosphodiesterases of bovine liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348175"}
{"pmid": "4348176", "title": "Purification of a soluble adenosine 5'-phosphosulphate sulphohydrolase from bovine liver.", "content": "Purification of a soluble adenosine 5'-phosphosulphate sulphohydrolase from bovine liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348176"}
{"pmid": "4348177", "title": "Isolation by affinity chromatography of neutral proteinase from Clostridium histolyticum.", "content": "Isolation by affinity chromatography of neutral proteinase from Clostridium histolyticum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348177"}
{"pmid": "4348179", "title": "Effect of prostaglandins E 1 , E 2  and A 2  on vascular resistance and responses to noradrenaline, nerve stimulation and angiotensin in the dog hindlimb.", "content": "Effect of prostaglandins E 1 , E 2  and A 2  on vascular resistance and responses to noradrenaline, nerve stimulation and angiotensin in the dog hindlimb. 1. The relationship between the vasodilator and inhibitory effects of prostaglandin E(1) (PGE(1)), E(2) and A(2) on responses to nerve stimulation, noradrenaline and angiotensin was evaluated in the dog hindlimb preparation.2. PGE(1) and PGE(2) were equipotent as vasodilators in the hindlimb; however, PGE(1) was much more potent as an inhibitor of vasoconstrictor responses to nerve stimulation, noradrenaline and angiotensin.3. PGA(2) and PGE(2) were approximately equal as inhibitors of vasoconstrictor responses to noradrenaline, nerve stimulation and angiotensin; however, PGE(2) was far more potent as a vasodilator.4. Since there is no relationship between the vasodilator and inhibitory effects of PGE(1), E(2) and A(2), and since the inhibitory effect of PGA(2) was present at a time when hindlimb perfusion pressure had returned to control value, it is concluded that the inhibitory action is probably not the result of a physiological antagonism.5. Since each prostaglandin inhibited responses to nerve stimulation and noradrenaline to approximately the same extent and responses to angiotensin were also inhibited, it is suggested that these agents antagonize vasoconstrictor responses by a nonspecific depressant effect on smooth muscle cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348179"}
{"pmid": "4348178", "title": "The effects of some phosphodiesterase inhibitors on the conductance of the perfused vascular beds of the chloralosed cat.", "content": "The effects of some phosphodiesterase inhibitors on the conductance of the perfused vascular beds of the chloralosed cat. 1. The vasoactivity of a number of phosphodiesterase inhibitors in the auto-perfused splanchnic region and hindquarters of the cat have been investigated.2. Theophylline, dipyridamole and 4-(3,4-dimethoxybenzyl)-2-imidazolidinone (Ro 7-2956) and its analogues were more potent vasodilators in the splanchnic region than in the hindquarters, whereas papaverine was a potent vasodilator in both these vascular beds.3. The vasodilator response to the phosphodiesterase inhibitors in the splanchnic region and hindquarters was not susceptible to beta-adrenoceptor blockade.4. Infusion of dibutyryl cyclic AMP into the superior mesenteric artery increased vascular conductance of the splanchnic region. This effect was enhanced by Ro 20-1724 in doses below those in which this compound affected conductance.5. These results are consistent with the hypothesis that accumulation of cyclic AMP in vascular smooth muscle mediates the vasodilator response to phosphodiesterase inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348178"}
{"pmid": "4348181", "title": "Augmentation of drug-induced blood pressure increases in rats by amorbarbital.", "content": "Augmentation of drug-induced blood pressure increases in rats by amorbarbital. The effects of amobarbital anaesthesia on blood pressure responses to angiotensin and noradrenaline were determined in rats with chronically implanted venous and aortic catheters. Responses were tested twice on the same day in each rat, first in the conscious state and then during anaesthesia. Blood pressure rises produced by noradrenaline and angiotensin were larger when the rats were anaesthetized with amobarbital than when they were conscious. This enhancement was not characteristic of general anaesthesia since urethane, instead of enhancing, depressed the pressor responses.Blockade of acetylcholine receptors with atropine also increased the response to pressor drugs. However, amobarbital in anaesthetic doses did not affect the response to acetylcholine, indicating that removal of compensatory parasympathetic reflexes was not a major cause of its enhancing effect. The effects of amobarbital on arterial pressure and heart rate were similar to those of the ganglion blocking drug pentolinium. When pressor responses were increased by amobarbital, autonomic ganglia were depressed as indicated by the loss of the response to nicotine. These findings suggest that amobarbital enhances blood pressure responses to noradrenaline and angiotensin by blocking autonomic ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348181"}
{"pmid": "4348180", "title": "The effect of cold storage on the inhibitory action of isoprenaline, phenylephrine and nicotine on the mechanical and membranal activities of guinea-pig taenia caecum.", "content": "The effect of cold storage on the inhibitory action of isoprenaline, phenylephrine and nicotine on the mechanical and membranal activities of guinea-pig taenia caecum. 1. The effects of prolonged cold storage on the mechanical and membranal responses to stimulation of alpha- and beta-adrenoceptors by phenylephrine and isoprenaline, respectively, were studied on the guinea-pig taenia caecum.2. Cold storage invariably caused a decrease in the resting membrane potential, and this effect was enhanced as the duration of treatment was prolonged.3. After cold storage (18 days) the tissue potassium ion content (89.7 +/- 1.7 mmol/kg wet wt.) was decreased to 30.5 +/- 1.9 mmol/kg wet wt. whereas that for sodium (69.2 +/- 1.4 mmol/kg wet wt.) increased to 134.0 +/- 2.3 mmol/kg wet wt.4. In the fresh preparations, phenylephrine (1 and 2 muM) caused a cessation of spontaneous action potentials, accompanied by hyperpolarization of the membrane and relaxation of the muscle. These effects were markedly diminished after 18 days of cold storage. Isoprenaline (1 and 2 muM) also blocked the action potentials and caused a concomitant muscle relaxation, but in most cases the hyperpolarization was not observed. After 14 days of cold storage these mechanical and membranal changes associated with isoprenaline treatment were not demonstrable in most preparations.5. Nicotine (5 muM and 50 muM) produced a biphasic effect, cessation of the action potential, hyperpolarization and subsequent relaxation followed by a long lasting depolarization, an accelerated discharge of action potentials and an increase in muscle tension. After a few days of cold storage the hyperpolarization effect disappeared but the intensity of the long-lasting depolarization as well as the contractile effects were increased. After cold storage for more than 7 days, nicotine did not affect mechanical or electrical activity.6. Dibutyryl 3'5' cyclic AMP (1 muM to 500 muM) failed to affect the mechanical and electrical activities of taenia caecum.7. Phenylephrine and isoprenaline had no effect on the high potassiumdepolarized taenia.8. These observations suggest that the electro-mechanical effect of an alpha-adrenoceptor stimulant on the guinea-pig taenia caecum is more resistant to cold treatment than that of a beta-adrenoceptor stimulant. This inhibitory system of stimulation of both a- and 8-receptors of guinea-pig taenia caecum may react by different mechanisms. The results also demonstrate that cold storage itself changes the membrane permeability to ions and the tissue ion content (Na+ and K+) of smooth muscle of guinea-pig taenia caecum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348180"}
{"pmid": "4348182", "title": "The effect of N6,O2'-dibutyryl adenosine 3':5'-cyclic monophosphate on noradrenaline synthesis in isolated superior cervical ganglia.", "content": "The effect of N6,O2'-dibutyryl adenosine 3':5'-cyclic monophosphate on noradrenaline synthesis in isolated superior cervical ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348182"}
{"pmid": "4348183", "title": "Studies on the mode of action of cyclic 3'5'-AMP and prostaglndin E 2  on rat gastric acid secretion and mucosal blood flow.", "content": "Studies on the mode of action of cyclic 3'5'-AMP and prostaglndin E 2  on rat gastric acid secretion and mucosal blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348183"}
{"pmid": "4348184", "title": "The effect of some synthetic analogues of ACTH on the metabolism of biogenic amines in the rat brain.", "content": "The effect of some synthetic analogues of ACTH on the metabolism of biogenic amines in the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348184"}
{"pmid": "4348185", "title": "Estimation of angiotensin II blood concentrations in hypertensive rats.", "content": "Estimation of angiotensin II blood concentrations in hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348185"}
{"pmid": "4348187", "title": "Effect of chlorpromazine on REM rebound in normal volunteers.", "content": "Effect of chlorpromazine on REM rebound in normal volunteers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348187"}
{"pmid": "4348186", "title": "Recurrent hyperkalaemia due to selective aldosterone deficiency: correction by angiotensin infusion.", "content": "Recurrent hyperkalaemia due to selective aldosterone deficiency: correction by angiotensin infusion. A patient with recurrent weakness and blurring of consciousness associated with hyperkalaemia due to aldosterone deficiency is reported. The plasma concentrations of renin, angiotensin II, and aldosterone were low and did not increase during sodium deprivation. Blood angiotensin I was also low while renin-substrate concentration was normal. Infusion of angiotensin produced a distinct rise in plasma aldosterone. The patient was treated successfully with fludrocortisol.The results support the concept that the renin-angiotensin system is an important regulator of aldosterone secretion and that in the syndrome of acquired selective hypoaldosteronism the primary abnormality may be a deficiency of renin. It is suggested that a selective lack of aldosterone should be considered in all cases of otherwise unexplained hyperkalaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348186"}
{"pmid": "4348191", "title": "Evidence that pepsitensin is angiotensin I.", "content": "Evidence that pepsitensin is angiotensin I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348191"}
{"pmid": "4348192", "title": "Selective suppression of rapid eye movement sleep (REM) by fusaric acid, an inhibitor of dopamine- -oxidase.", "content": "Selective suppression of rapid eye movement sleep (REM) by fusaric acid, an inhibitor of dopamine- -oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348192"}
{"pmid": "4348193", "title": "Electron microscopic observations of neocarzinostatin treated Burkitt lymphoma cells.", "content": "Electron microscopic observations of neocarzinostatin treated Burkitt lymphoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348193"}
{"pmid": "4348194", "title": "The finding of viral particles in spontaneous mammary adenocarcinoma in rats.", "content": "The finding of viral particles in spontaneous mammary adenocarcinoma in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348194"}
{"pmid": "4348195", "title": "Co-existence of a guanidine-dependence and of a thiopyrimidine dependence in the same strain of poliovirus.", "content": "Co-existence of a guanidine-dependence and of a thiopyrimidine dependence in the same strain of poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348195"}
{"pmid": "4348196", "title": "Preparation and biological activity of some anthyridine derivatives.", "content": "Preparation and biological activity of some anthyridine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348196"}
{"pmid": "4348198", "title": "Adenoviral infection in foals.", "content": "Adenoviral infection in foals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348198"}
{"pmid": "4348199", "title": "Cerebral malformation in fetal lambs from a bluetongue-enzootic flock.", "content": "Cerebral malformation in fetal lambs from a bluetongue-enzootic flock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348199"}
{"pmid": "4348200", "title": "Characterization of the 4-acetamido-4,6-dideoxyhexoses from Escherichia coli strains.", "content": "Characterization of the 4-acetamido-4,6-dideoxyhexoses from Escherichia coli strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348200"}
{"pmid": "4348201", "title": "Properties of 5-phosphoribosyl-1-pyrophosphate amidotransferase from human lymphoblasts.", "content": "Properties of 5-phosphoribosyl-1-pyrophosphate amidotransferase from human lymphoblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348201"}
{"pmid": "4348202", "title": "Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties.", "content": "Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348202"}
{"pmid": "4348203", "title": "Genetic regulation of aryl hydrocarbon hydroxylase induction. V. Specific changes in spin state of cytochrome P 450  from genetically responsive animals.", "content": "Genetic regulation of aryl hydrocarbon hydroxylase induction. V. Specific changes in spin state of cytochrome P 450  from genetically responsive animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348203"}
{"pmid": "4348204", "title": "Dissociation and activation of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases by cyclic nucleotides and by substrate proteins.", "content": "Dissociation and activation of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases by cyclic nucleotides and by substrate proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348204"}
{"pmid": "4348205", "title": "Protein kinase modulator from lobster tail muscle. I. Stimulatory and inhibitory effects of the modulator on the phosphorylation of substrate proteins by guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases.", "content": "Protein kinase modulator from lobster tail muscle. I. Stimulatory and inhibitory effects of the modulator on the phosphorylation of substrate proteins by guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348205"}
{"pmid": "4348206", "title": "Protein kinase modulator from lobster tail muscle. II. Effects of the modulator on holoenzyme and catalytic subunit of guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases.", "content": "Protein kinase modulator from lobster tail muscle. II. Effects of the modulator on holoenzyme and catalytic subunit of guanosine 3',5'-monophosphate-dependent and adenosine 3',5'-monophosphate-dependent protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348206"}
{"pmid": "4348207", "title": "Phenylalanine hydroxylase in cultured hepatoxytes. I. Hormonal control of enzyme levels.", "content": "Phenylalanine hydroxylase in cultured hepatoxytes. I. Hormonal control of enzyme levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348207"}
{"pmid": "4348208", "title": "Separate oxidase and reductase reaction sites on cytochrome c demonstrated with purified site-specific antibodies.", "content": "Separate oxidase and reductase reaction sites on cytochrome c demonstrated with purified site-specific antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348208"}
{"pmid": "4348209", "title": "Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance.", "content": "Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348209"}
{"pmid": "4348210", "title": "Studies on the mechanism of action of uridine diphosphate galactose 4-epimerase. II. Substrate-dependent reduction by sodium borohydride.", "content": "Studies on the mechanism of action of uridine diphosphate galactose 4-epimerase. II. Substrate-dependent reduction by sodium borohydride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348210"}
{"pmid": "4348211", "title": "Enzyme secretion mediated by the epinephrine  -receptor in rat parotid slices. Factors governing efficiency of the process.", "content": "Enzyme secretion mediated by the epinephrine  -receptor in rat parotid slices. Factors governing efficiency of the process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348211"}
{"pmid": "4348212", "title": "Potassium release mediated by the epinephrine  -receptor in rat parotid slices. Properties and relation to enzyme secretion.", "content": "Potassium release mediated by the epinephrine  -receptor in rat parotid slices. Properties and relation to enzyme secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348212"}
{"pmid": "4348213", "title": "Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.", "content": "Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348213"}
{"pmid": "4348214", "title": "The mechanism of the water expulsion vesicle of the ciliate Tetrahymena pyriformis.", "content": "The mechanism of the water expulsion vesicle of the ciliate Tetrahymena pyriformis. Analysis of high-speed (150 frames/sec) cinematographs of the filling and expulsion of the water expulsion vesicle of Tetrahymena pyriformis shows that the vesicle fills as water is pumped into it by contractions of at least four ampullary sacs which are continuous with the endoplasmic reticulum. When filled, the vesicle is pressed against its two excretory pores by cyclotic movements of the cytoplasm. This pressure closes the apertures of the ampullae, preventing backflow from the vesicle into them, and also spreads the pellicle of and at the pore, thereby stretching and rupturing the pore-sealing membrane. The vesicle is then invaginated by the cytoplasmic pressure, driving fluid out of the pore. The pore-sealing membrane then reforms, apparently by constriction, and the vesicle is again filled. Electron micrographs show that crisscrossed pore-microtubules extend from the pore to the openings of the ampullae, anchoring the vesicle in place. Each pore is surrounded by a stack of at least 11 ring-microtubules, to which the anchoring pore-microtubules are attached. The pore-microtubules appear to exert tension which assists in spreading the pore, aiding cyclotic pressures in rupturing the pore-sealing membrane. A possible mechanism for the cyclotic pressure and ampullary contraction is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348214"}
{"pmid": "4348215", "title": "Nematosomes in the rat trigeminal ganglion.", "content": "Nematosomes in the rat trigeminal ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348215"}
{"pmid": "4348216", "title": "Ultrastructural studies of cell-virus interaction in reptilian cell lines. I. Intramitochondrial viruses in \"C-type\" virus-producing VSW cells.", "content": "Ultrastructural studies of cell-virus interaction in reptilian cell lines. I. Intramitochondrial viruses in \"C-type\" virus-producing VSW cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348216"}
{"pmid": "4348218", "title": "Transplantation immunity to simian virus 40-transformed cells in tumor-bearing mice. I. Development of cellular immunity to simian virus 40 tumor-specific transplantation antigens during tumorigenesis by transplanted cells.", "content": "Transplantation immunity to simian virus 40-transformed cells in tumor-bearing mice. I. Development of cellular immunity to simian virus 40 tumor-specific transplantation antigens during tumorigenesis by transplanted cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348218"}
{"pmid": "4348217", "title": "Susceptibility of mammalian (hamster) cell culture to infection with cellular and cell-free type II leukosis (Marek's disease) virus.", "content": "Susceptibility of mammalian (hamster) cell culture to infection with cellular and cell-free type II leukosis (Marek's disease) virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348217"}
{"pmid": "4348219", "title": "Transplantation immunity to simian virus 40-transformed cells in tumor-bearing mice. II. Evidence for macrophage participation at the effector level of tumor cell rejection.", "content": "Transplantation immunity to simian virus 40-transformed cells in tumor-bearing mice. II. Evidence for macrophage participation at the effector level of tumor cell rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348219"}
{"pmid": "4348220", "title": "Enhanced tumor growth in animals pretreated with complete Freund's adjuvant.", "content": "Enhanced tumor growth in animals pretreated with complete Freund's adjuvant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348220"}
{"pmid": "4348221", "title": "Effect of treatment of C57BL-6 mice with the methanol extraction residue fraction of BCG on leukemogenesis induced by the radiation leukemia virus.", "content": "Effect of treatment of C57BL-6 mice with the methanol extraction residue fraction of BCG on leukemogenesis induced by the radiation leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348221"}
{"pmid": "4348222", "title": "Activation of a type-C RNA virus from tumors induced by rat kidney cells transformed by a chemical carcinogen.", "content": "Activation of a type-C RNA virus from tumors induced by rat kidney cells transformed by a chemical carcinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348222"}
{"pmid": "4348223", "title": "Preparation of pure cultures of tumor macrophages.", "content": "Preparation of pure cultures of tumor macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348223"}
{"pmid": "4348224", "title": "Morphogenesis of C-type and A-type particles in cells infected by an arbovirus.", "content": "Morphogenesis of C-type and A-type particles in cells infected by an arbovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348224"}
{"pmid": "4348226", "title": "Brain tumors induced by Rous sarcoma virus, Schmidt-Ruppin strain. 3. Morphology of brain tumors induced in adult mice.", "content": "Brain tumors induced by Rous sarcoma virus, Schmidt-Ruppin strain. 3. Morphology of brain tumors induced in adult mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348226"}
{"pmid": "4348225", "title": "Effect of CCNU (NSC-79037) on bronchogenic carcinoma.", "content": "Effect of CCNU (NSC-79037) on bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348225"}
{"pmid": "4348227", "title": "A case of leprous nodular interstitial myositis.", "content": "A case of leprous nodular interstitial myositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348227"}
{"pmid": "4348228", "title": "Autoxidation of polyunsaturated fatty esters on silica.", "content": "Autoxidation of polyunsaturated fatty esters on silica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348228"}
{"pmid": "4348229", "title": "Malignant lymphoma. 1.", "content": "Malignant lymphoma. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348229"}
{"pmid": "4348231", "title": "Parasympathetic control of the heart.", "content": "Parasympathetic control of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348231"}
{"pmid": "4348232", "title": "The PARA-adenoviruses.", "content": "The PARA-adenoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348232"}
{"pmid": "4348237", "title": "Annular nucleolus in Leydig cells of mouse.", "content": "Annular nucleolus in Leydig cells of mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348237"}
{"pmid": "4348238", "title": "Electron microscopic study on the thyroid gland of the salamander Hynobius nebulosus in the breeding season. I. Observation under normal conditions.", "content": "Electron microscopic study on the thyroid gland of the salamander Hynobius nebulosus in the breeding season. I. Observation under normal conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348238"}
{"pmid": "4348239", "title": "Electron microscopic study on the thyroid gland of the salamander Hynobius nebulosus in the breeding season. II. Observation under experimental conditions.", "content": "Electron microscopic study on the thyroid gland of the salamander Hynobius nebulosus in the breeding season. II. Observation under experimental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348239"}
{"pmid": "4348240", "title": "Synaptic junction development in the spinal cord of an amphibian embryo: an electron microscope study.", "content": "Synaptic junction development in the spinal cord of an amphibian embryo: an electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348240"}
{"pmid": "4348242", "title": "The effect of enzymes on extracellular connective tissue components in the developing chick aorta.", "content": "The effect of enzymes on extracellular connective tissue components in the developing chick aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348242"}
{"pmid": "4348243", "title": "Ultrastructural study of virilizing adrenocortical adenoma.", "content": "Ultrastructural study of virilizing adrenocortical adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348243"}
{"pmid": "4348244", "title": "Enterovirus surveillance following a community-wide oral poliovirus vaccination program: a seven-year study.", "content": "Enterovirus surveillance following a community-wide oral poliovirus vaccination program: a seven-year study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348244"}
{"pmid": "4348245", "title": "Acute respiratory disease in military trainees: the adenovirus surveillance program, 1966-1971.", "content": "Acute respiratory disease in military trainees: the adenovirus surveillance program, 1966-1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348245"}
{"pmid": "4348247", "title": "Significance and treatment of lymph node metastases of malignant mucous and salivary gland tumors.", "content": "Significance and treatment of lymph node metastases of malignant mucous and salivary gland tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348247"}
{"pmid": "4348246", "title": "Immunoglobulin response and viremia in dengue-vaccinated gibbons repeatedly challenged with Japanese encephalitis virus.", "content": "Immunoglobulin response and viremia in dengue-vaccinated gibbons repeatedly challenged with Japanese encephalitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348246"}
{"pmid": "4348248", "title": "Superior vena caval syndrome: scintiphotographic evaluation of response to radiation therapy.", "content": "Superior vena caval syndrome: scintiphotographic evaluation of response to radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348248"}
{"pmid": "4348249", "title": "Inferior phrenic artery collateralization in hepatic artery occlusion.", "content": "Inferior phrenic artery collateralization in hepatic artery occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348249"}
{"pmid": "4348250", "title": "Mixed mesodermal sarcoma of the uterus.", "content": "Mixed mesodermal sarcoma of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348250"}
{"pmid": "4348251", "title": "An attempt to clarify the immunobiological significance of Mott's cells.", "content": "An attempt to clarify the immunobiological significance of Mott's cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348251"}
{"pmid": "4348254", "title": "Inhibition of poliovirus multiplication by a normal horse serum. I. Characterization of virus-inhibitor interaction.", "content": "Inhibition of poliovirus multiplication by a normal horse serum. I. Characterization of virus-inhibitor interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348254"}
{"pmid": "4348252", "title": "Oxidative phosphorylation in intact bacteria.", "content": "Oxidative phosphorylation in intact bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348252"}
{"pmid": "4348255", "title": "The pressor effect of angiotensin II in pregnant sheep.", "content": "The pressor effect of angiotensin II in pregnant sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348255"}
{"pmid": "4348256", "title": "Genetic and biochemical studies of the adrenal lipid depletion phenotype in mice.", "content": "Genetic and biochemical studies of the adrenal lipid depletion phenotype in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348256"}
{"pmid": "4348257", "title": "Genetic relationships between the multiple alcohol dehydrogenases of maize.", "content": "Genetic relationships between the multiple alcohol dehydrogenases of maize.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348257"}
{"pmid": "4348258", "title": "Biosynthesis of geraniol and nerol and beta-D-glucosides in Pelargonium graveolens and Rosa dilecta.", "content": "Biosynthesis of geraniol and nerol and beta-D-glucosides in Pelargonium graveolens and Rosa dilecta. 1. 3R-[2-(14)C]Mevalonate was incorporated into geranyl and neryl beta-d-glucosides in petals of Rosa dilecta in up to 10.6% yield, and the terpenoid part was specifically and equivalently labelled in the moieties derived from isopentenyl pyrophosphate and 3,3-dimethylallyl pyrophosphate. A similar labelling pattern, with incorporations of 0.06-0.1% was found for geraniol or nerol formed in leaves of Pelargonium graveolens The former results provide the best available evidence for the mevalonoid route to regular monoterpenes in higher plants. 2. Incorporation studies with 3RS-[2-(14)C,(4R)-4-(3)H(1)]-mevalonate and its (4S)-isomer showed that the pro-4R hydrogen atom of the precursor was retained and the pro-4S hydrogen atom was eliminated in both alcohols and both glucosides. These results suggest that the correlation of retention of the pro-4S hydrogen atom of mevalonate with formation of a cis-substituted double bond, such as has been found in certain higher terpenoids, does not apply to the biosynthesis of monoterpenes. It is proposed that either nerol is derived from isomerization of geraniol or the two alcohols are directly formed by different prenyltransferases. Possible mechanisms for these processes are discussed. 3. The experiments with [(14)C,(3)H]mevalonate also show that in these higher plants, as has been previously found in animal tissue and yeast, the pro-4S hydrogen atom of mevalonate was lost in the conversion of isopentenyl pyrophosphate into 3,3-dimethylallyl pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348258"}
{"pmid": "4348259", "title": "Isolation and characterization of membranes from normal and transformed tissue-culture cells.", "content": "Isolation and characterization of membranes from normal and transformed tissue-culture cells. Homogenates of baby-hamster kidney cells and rat embryo fibroblasts prepared by nitrogen cavitation contain a small population of slowly sedimenting mitochondria or mitochondrial fragments, which contaminate the microsomal fraction. This appears to limit the resolution of surface membrane and endoplasmic reticulum on magnesium-containing dextran gradients. The microsomal material and mitochondria can, however, be completely separated on a 10-60% (w/w) sucrose zonal gradient containing a 30% sucrose plateau. On magnesium-containing dextran gradients this mitochondria-free microsomal material can be resolved into at least two surface membrane fractions and at least two endoplasmic reticulum fractions. Comparison of polyoma virus-transformed and normal baby-hamster kidney cells reveals some interesting differences in their microsomal fractionation patterns and the characteristics of the Na(+)/K(+)-Mg(2+) adenosine triphosphatase of their surface membranes, in particular a tenfold lower K(m) in the virus-transformed cells. The fractionation patterns of normal and spontaneously transformed rat embryo fibroblasts are also briefly discussed, particularly in relation to the significance of the observation that both the surface membrane and endoplasmic reticulum from these cells can be subfractionated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348259"}
{"pmid": "4348260", "title": "The regulation of rabbit liver fructose 1,6-diphosphatase activity by phospholipids in vitro.", "content": "The regulation of rabbit liver fructose 1,6-diphosphatase activity by phospholipids in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348260"}
{"pmid": "4348261", "title": "Evidence for modification of protein phosphorylation by cytokinins.", "content": "Evidence for modification of protein phosphorylation by cytokinins. Kinetin stimulated phosphorylation of protein in floated Chinese-cabbage leaf discs, but inhibited protein phosphorylation in nuclei+chloroplast extracts from Chinese-cabbage or tobacco leaves. Kinetin also inhibited protein phosphorylation in isolated tobacco nuclei or nuclei from carrot secondary-phloem tissue. Purified Chinese-cabbage leaf ribosomes exhibited protein kinase activity which was inhibited by kinetin and zeatin. The ribosome-associated kinase responded to kinetin and zeatin differently from that associated with nuclei+chloroplast preparations. Protein phosphorylation in vitro was not affected by adenosine 3':5'-cyclic monophosphate, indol-3-ylacetic acid or gibberellic acid. It was only inhibited by N(9)-unsubstituted purines, among which the known cytokinins were the most effective inhibitors. The results are discussed in relation to possible similarities between the effects of cytokinins in plant tissues and the effects of adenosine 3':5'-cyclic monophosphate in animal tissues. Both compounds appear to modify the activity of protein kinases and both affect many different cellular processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348261"}
{"pmid": "4348262", "title": "Isolation and characterization of lipoprotein B from high-density human serum lipoproteins.", "content": "Isolation and characterization of lipoprotein B from high-density human serum lipoproteins. 1. Lipoprotein B from female Lp(a)-lipoprotein-negative serum was isolated from the fraction of density 1.073-1.125 by using immunoadsorbent; 2.5mg of freeze-dried material was obtained from 100ml of serum from a fasting patient. 2. The hydrated density of this lipoprotein was found to be 1.084g/cm(3). A flotation rate F(1.200) of 9.4 and lipid/protein ratio 1.40 were found, similar to that of high-density (d 1.073-1.125) lipoprotein preparations. 3. From immunochemical and electrophoretic studies of the intact and totally delipidized lipoprotein B it was concluded that this lipoprotein represents a separate family within the high-density range of human serum lipoproteins. 4. The possibility that the isolated lipoprotein B is an artifact created by the isolation procedure is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348262"}
{"pmid": "4348264", "title": "Can Culex pipiens fatigans or Aedes aegypti spread smallpox? A preliminary report.", "content": "Can Culex pipiens fatigans or Aedes aegypti spread smallpox? A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348264"}
{"pmid": "4348263", "title": "Development of the activities of enzymes of the isoprenoid pathway during early stages of pea-seed germination.", "content": "Development of the activities of enzymes of the isoprenoid pathway during early stages of pea-seed germination. The activities of individual enzymes of the isoprenoid pathway from mevalonate kinase to squalene synthetase in homogenates of seeds germinated up to 32h were assayed. Changes in the activity of each enzyme were observed and compared with the activity at the 2h germination stage. Activities of alkaline phosphatase and fructose 1,6-diphosphate aldolase were similarly measured to provide a reference for changes in the general metabolic activity of seeds during imbibition of water. Water uptake reached a plateau after 12h. The reference enzymes almost doubled in activity between 2 and 8h and thereafter their activities steadily declined. All of the enzymes of the isoprenoid pathway increased in activity between 2 and 6h and, thereafter, with the exception of the prenyltransferase, their activities remained relatively constant. With the prenyltransferase activity the initial increase was followed by a short plateau between 6 and 9h and then a second increase to a maximum between 14 and 16h. After 16h the activity declined. The relative activities of the isoprenoid enzymes at 16h of germination were mevalonate kinase>phosphomevalonate kinase>pyrophosphomevalonate decarboxylase approximately isopentenyl pyrophosphate isomerase>squalene synthetase>isopentenyl pyrophosphate/dimethylallyl pyrophosphate prenyltransferase. The finding that the prenyltransferase may be the rate-limiting enzyme in squalene synthesis from mevalonate is discussed in relation to regulation of isoprenoid synthesis during pea-seed germination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348263"}
{"pmid": "4348265", "title": "Proteolytic activity of Entamoeba histolytica. 1. Detection of enzyme by photographic film band.", "content": "Proteolytic activity of Entamoeba histolytica. 1. Detection of enzyme by photographic film band.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348265"}
{"pmid": "4348266", "title": "The identification of the enzymes that catalyse the oxidation of glyoxylate to oxalate in the 100000 g supernatant fraction of human hyperoxaluric and control liver and heart tissue.", "content": "The identification of the enzymes that catalyse the oxidation of glyoxylate to oxalate in the 100000 g supernatant fraction of human hyperoxaluric and control liver and heart tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348266"}
{"pmid": "4348272", "title": "Electron microscopic evidence of the subviral oncogenic particles (virosomes) isolated from the mitochondria of Rous sarcoma cells.", "content": "Electron microscopic evidence of the subviral oncogenic particles (virosomes) isolated from the mitochondria of Rous sarcoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348272"}
{"pmid": "4348273", "title": "Classroom approach teaches patients independence skills.", "content": "Classroom approach teaches patients independence skills.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348273"}
{"pmid": "4348274", "title": "Hospital takes group therapy to released alcoholics in distant community.", "content": "Hospital takes group therapy to released alcoholics in distant community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348274"}
{"pmid": "4348275", "title": "A drug unit for life-style change: the Tellurian community.", "content": "A drug unit for life-style change: the Tellurian community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348275"}
{"pmid": "4348276", "title": "The production of vesicular stomatitis virus by antigen- or mitogen-stimulated lymphocytes and continuous lymphoblastoid lines.", "content": "The production of vesicular stomatitis virus by antigen- or mitogen-stimulated lymphocytes and continuous lymphoblastoid lines. A variety of lymphoid cell populations were examined in terms of their ability to replicate vesicular stomatitis virus (VSV), a lytic, RNA-containing virus maturing at the cell surface. The number of cells capable of producing VSV was estimated in terms of infectious centers by the virus plaque assay (VPA), and morphologically by electron microscopy (EM). The lymphoid cells examined in this study included: (a) lymph node cells from delayed hypersensitive guinea pigs stimulated by specific antigen, (b) mouse spleen cells activated by selective bone marrow-derived (B) cell and thymus derived (T) cell mitogens, and (c) cells of human and murine continuous lymphoblastoid or lymphoma lines. In unstimulated cultures of guinea pig lymph node cells there is a background of approximately 1 in 1,000 cells which produces VSV; in purified protein derivative (PPD)-stimulated cultures the number of cells producing virus was 1.6% in the VPA and 1.9% by EM. These cells were large lymphocytes with some morphological features of transformed lymphocytes but were not typical blast cells. A few macrophages were associated with virus in both stimulated and control cultures. These observations indicate that (a) cells responsive to antigens, as detected by a marker virus, were lymphocytes; (b) cells other than lymphocytes (macrophages) were capable of replicating VSV even without antigenic stimulation; and (c) the correlation of results obtained by VPA and morphologic examination was usually quite good. Of the total number of mouse spleen cells stimulated with concanavalin (Con A), a T cell mitogen, 4.5 (EM)-5.7% (VPA) were associated with VSV. These were characteristic transformed lymphocytes, similar to phytohemagglutinin (PHA)-stimulated human lymphocytes. In contrast Escherichia coli lipopolysaccharide (LPS)-treated mouse spleen cultures contained lower numbers of virus plaque-forming cells. The majority of such cells associated with virus displayed extensive rough endoplasmic reticulum. Two cultured murine lymphomas containing lymphocytes with the theta surface marker (L5178Y and EL-4) showed a 15-100-fold higher incidence of virus-producing cells than leukemias (L1210 and C57Bl/6) which did not carry this marker. Similarly, the L2C guinea pig leukemia, a known B cell leukemia, yielded a low percent of virus plaque-forming cells (<2%). However, MOPC-104, a plasma cell tumor presumed to be of B cell origin, was found to be an efficient virus producer. There was a wide variation in the efficiency of VSV replication among human lymphoblastoid lines. One line, Wil-2, produced 80% infectious centers after 24 h of exposure to VSV, and all cells were associated with virus at the EM level. The relationship between the virus-producing cells and different lymphocyte subpopulations as well as the efficiency of the two assays for studying virus-producing lymphocytes is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348276"}
{"pmid": "4348278", "title": "Induction of arginase activity with the Shope papilloma virus in tissue culture cells from an argininemic patient.", "content": "Induction of arginase activity with the Shope papilloma virus in tissue culture cells from an argininemic patient. Inoculation of the Shope virus in tissue cultures of human fibroblasts from a patient with a deficiency of the enzyme arginase results in an induction of arginase activity, apparently virus coded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348278"}
{"pmid": "4348277", "title": "The effect of Bordetella pertussis on lymphocyte cyclic AMP metabolism.", "content": "The effect of Bordetella pertussis on lymphocyte cyclic AMP metabolism. Bordetella pertussis culture fractions produce decreased metabolic responses to isoproterenol and epinephrine in mice and rats, suggesting the possibility of systemic beta adrenergic blockade. The present study was undertaken to elucidate the mechanism of the alteration in adrenergic responsiveness and to clarify its relationship to other biological effects of the organism. Lymphocytes were selected as a suitable tissue because of the marked alteration in lymphocyte distribution in pertussis-treated mice and rats, suggesting a change in the surface properties of these cells. Human peripheral blood lymphocytes, purified by nylon fiber chromatography, were studied. In short incubation experiments (20 min or less) B. pertussis did not alter the cyclic AMP response to isoproterenol, prostaglandin E (PGE(1)), or methacholine. However, when cells were preincubated with B. pertussis for 90 min at 37 degrees C, the responses to all three agents were markedly inhibited. Although these observations provide direct confirmation of the ability of B. pertussis to inhibit catecholamine responsiveness, the fact that PGE(1) and methacholine responses were also inhibited suggests that blockade at the level of the beta adrenergic receptor is doubtful. The inhibitory activity was localized in a nondialyzable, protein-rich fraction that is precipitated from B. pertussis culture fluid by ammonium sulfate at 90% of saturation. The bulk of the activity was obtained in the load volume after 50,000 g centrifugation in a cesium chloride gradient, density 1.2-1.5 (fraction 4). Fraction 4 produced a change in lymphocyte hormonal responsiveness at concentrations as low as 5 ng/ml. The relationship between cyclic AMP inhibitory activity in isolated human cells and leukocytosis-producing activity in intact mice was studied. The two activities seemed to parallel one another quite closely until the final Sephadex G-150 fractionation step, in which the two activities were obtained in the same column fraction, but a greater recovery of the leukocytosis-producing activity was obtained. Additional purification will be required to establish conclusively whether the same macromolecule is responsible for both activities. The availability of a bacterial product that markedly inhibits cyclic AMP accumulation in purified lymphocytes may help to clarify the role of cyclic AMP in lymphocyte activation by antigen and nonspecific mitogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348277"}
{"pmid": "4348279", "title": "Relation of chromosome 4 (linkage group 8) to murine leukemia virus-associated antigens of AKR mice.", "content": "Relation of chromosome 4 (linkage group 8) to murine leukemia virus-associated antigens of AKR mice. Genes specifying or controlling the expression of G(IX) (cell surface), GCSA (cell surface), and gs (internal viral) antigens are located in chromosome 4 (linkage group [LG] VIII) of the AKR mouse. All three antigens may exhibit mendelian inheritance, mice being antigen positive or antigen negative, but each may also appear in leukemic cells of mice whose inherited genotype was antigen negative. The G(IX)-determining gene in LG VIII of AKR mice apparently is equivalent to Gv-1, which determines expression of the same antigen in 129 strain mice, but which in the latter strain is located in LG IX. As the estimated distance of Gv-1 from H-2 in 129 mice is considerable (37 units) further tests are now indicated to assess the possibility of pseudolinkage in this case. The Fv-1 locus, also located in LG VIII, influences the mouse's titer of MuLV, and might thereby be thought to regulate the G(IX) and gs phenotypes of AKR backcross segregants. But the data indicate a discrete LG VIII locus for G(IX), since expression of this antigen is mendelian and independent of infectious virus titer. Since the G(IX) and GCSA phenotypes of AKR backcross segregants were invariably concordant, these two antigens must be specified or controlled by closely linked genes, and the latter also is presumably independent of virus titer. The question as to what extent expression of gs antigen in the segregants is secondary to virus production is undecided.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348279"}
{"pmid": "4348280", "title": "Radiographic and physiologic patterns among workers engaged in manufacture of asbestos cement products: a preliminary report.", "content": "Radiographic and physiologic patterns among workers engaged in manufacture of asbestos cement products: a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348280"}
{"pmid": "4348281", "title": "Antagonism of peripheral and central effects of angiotensin II by (1-sarcosine, 8-isoleucine)angiotensin II.", "content": "Antagonism of peripheral and central effects of angiotensin II by (1-sarcosine, 8-isoleucine)angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348281"}
{"pmid": "4348283", "title": "Metabolic factors involved in the interaction between pyrazole and butane-1,4-diol and 4-hydroxybutyric acid.", "content": "Metabolic factors involved in the interaction between pyrazole and butane-1,4-diol and 4-hydroxybutyric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348283"}
{"pmid": "4348282", "title": "Inhibition of lysosomal enzyme release by adenosine 5' triphosphate and N 6 ,O 2 -dibutyryl cyclic 3',5'-adenosine monophosphate.", "content": "Inhibition of lysosomal enzyme release by adenosine 5' triphosphate and N 6 ,O 2 -dibutyryl cyclic 3',5'-adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348282"}
{"pmid": "4348284", "title": "Effects of denervation and lack of calcium on the action of Latrodectus venom on rat sympathetic ganglion.", "content": "Effects of denervation and lack of calcium on the action of Latrodectus venom on rat sympathetic ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348284"}
{"pmid": "4348285", "title": "Effect of mineralocorticoid agonists and antagonists on binding of  3 H-aldosterone to adrenalectomized rat kidney plasma membranes.", "content": "Effect of mineralocorticoid agonists and antagonists on binding of  3 H-aldosterone to adrenalectomized rat kidney plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348285"}
{"pmid": "4348286", "title": "The inhibitory effects of theophylline feeding on gluconeogenic enzymes in rat liver.", "content": "The inhibitory effects of theophylline feeding on gluconeogenic enzymes in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348286"}
{"pmid": "4348287", "title": "Stimulation of mitochondrial DNA synthesis in HeLa cells by Herpes simplex virus.", "content": "Stimulation of mitochondrial DNA synthesis in HeLa cells by Herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348287"}
{"pmid": "4348288", "title": "Cyclic-AMP binding sites on the cell surface of thymic lymphocytes.", "content": "Cyclic-AMP binding sites on the cell surface of thymic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348288"}
{"pmid": "4348290", "title": "Isosmotic intracellular regulation and redox changes in the respiratory chain components of Callinectes sapidus isolated muscle fibers.", "content": "Isosmotic intracellular regulation and redox changes in the respiratory chain components of Callinectes sapidus isolated muscle fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348290"}
{"pmid": "4348289", "title": "Aortic proline hydroxylase in hypoxia induced arteriosclerosis in rabbits.", "content": "Aortic proline hydroxylase in hypoxia induced arteriosclerosis in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348289"}
{"pmid": "4348292", "title": "Hepatic surgery.", "content": "Hepatic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348292"}
{"pmid": "4348291", "title": "Increased phosphofructokinase concentration in hepatoma 3924-A: enzymic and immunological evidence.", "content": "Increased phosphofructokinase concentration in hepatoma 3924-A: enzymic and immunological evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348291"}
{"pmid": "4348293", "title": "Association of cervical cytomegaloviruses with venereal disease.", "content": "Association of cervical cytomegaloviruses with venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348293"}
{"pmid": "4348294", "title": "Hepatocyte specificity for  -foetoprotein production.", "content": "Hepatocyte specificity for  -foetoprotein production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348294"}
{"pmid": "4348295", "title": "A study on the levels of nucleic acids, protein and phosphatases in normal and X-irradiated guinea pigs.", "content": "A study on the levels of nucleic acids, protein and phosphatases in normal and X-irradiated guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348295"}
{"pmid": "4348300", "title": "Interactions of components of human rhinovirus type 2 with Hela cells.", "content": "Interactions of components of human rhinovirus type 2 with Hela cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348300"}
{"pmid": "4348301", "title": "Ribonucleases of Rous sarcoma virus.", "content": "Ribonucleases of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348301"}
{"pmid": "4348303", "title": "Simian virus 40 DNA integration within the genome of virus-transformed mammalian cells.", "content": "Simian virus 40 DNA integration within the genome of virus-transformed mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348303"}
{"pmid": "4348302", "title": "The nucleic acid of an SV40-like virus isolated from a patient with progressive multifocal leukoencephalopathy.", "content": "The nucleic acid of an SV40-like virus isolated from a patient with progressive multifocal leukoencephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348302"}
{"pmid": "4348304", "title": "An analysis of the physical and chemical factors involved in the reactivation of neutralized poliovirus by the method of freezing and thawing.", "content": "An analysis of the physical and chemical factors involved in the reactivation of neutralized poliovirus by the method of freezing and thawing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348304"}
{"pmid": "4348305", "title": "Host cell DNA synthesis as a possible factor in the enhancement of replication of human adenoviruses in simian cells by SV40.", "content": "Host cell DNA synthesis as a possible factor in the enhancement of replication of human adenoviruses in simian cells by SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348305"}
{"pmid": "4348306", "title": "Adenosine 3',5'-cyclic monophosphate regulation of chloramphenicol acetyltransferase synthesis in vitro from P1CM DNA.", "content": "Adenosine 3',5'-cyclic monophosphate regulation of chloramphenicol acetyltransferase synthesis in vitro from P1CM DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348306"}
{"pmid": "4348307", "title": "Polyacrylamide gel electrophoresis of fowlpox and vaccinia virus proteins.", "content": "Polyacrylamide gel electrophoresis of fowlpox and vaccinia virus proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348307"}
{"pmid": "4348308", "title": "Studies of SV40 DNA. VI. Cleavage of SV40 DNA by restriction endonuclease from Hemophilus parainfluenzae.", "content": "Studies of SV40 DNA. VI. Cleavage of SV40 DNA by restriction endonuclease from Hemophilus parainfluenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348308"}
{"pmid": "4348309", "title": "Morphological aspects of the hypothalamic-hypophyseal system. IV. Medial basal hypothalamus. An experimental morphological study.", "content": "Morphological aspects of the hypothalamic-hypophyseal system. IV. Medial basal hypothalamus. An experimental morphological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348309"}
{"pmid": "4348311", "title": "Profound cystic colitis. Colitis cystica profunda.", "content": "Profound cystic colitis. Colitis cystica profunda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348311"}
{"pmid": "4348310", "title": "Ultrastructural aspects of the nucleus infundibularis dorsalis in the caudal hypothalamus of Xenopus laevis.", "content": "Ultrastructural aspects of the nucleus infundibularis dorsalis in the caudal hypothalamus of Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348310"}
{"pmid": "4348312", "title": "Adenosine 3',5'--cyclic monophosphate dependent protein kinase and phosphoprotein phosphatase activities in rat islets of Langerhans.", "content": "Adenosine 3',5'--cyclic monophosphate dependent protein kinase and phosphoprotein phosphatase activities in rat islets of Langerhans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348312"}
{"pmid": "4348313", "title": "The preparation of a modified GTP-sepharose derivative and its use in the purification of dihydroneopterin triphosphate synthetase, the first enzyme in folate biosynthesis.", "content": "The preparation of a modified GTP-sepharose derivative and its use in the purification of dihydroneopterin triphosphate synthetase, the first enzyme in folate biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348313"}
{"pmid": "4348314", "title": "Effect of histamine of lipolysis and adenosine 3',5'-monophosphate levels in canine adipose tissue.", "content": "Effect of histamine of lipolysis and adenosine 3',5'-monophosphate levels in canine adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348314"}
{"pmid": "4348315", "title": "The mechanism of the nicotinamide adenine dinucleotide stimulation of lipid phosphorylation in a rat liver microsome-cytosol system.", "content": "The mechanism of the nicotinamide adenine dinucleotide stimulation of lipid phosphorylation in a rat liver microsome-cytosol system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348315"}
{"pmid": "4348317", "title": "Cell density dependent glycolipids in NILz hamster cells, derived malignant and transformed cell lines.", "content": "Cell density dependent glycolipids in NILz hamster cells, derived malignant and transformed cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348317"}
{"pmid": "4348316", "title": "Effect of phospholipids on lipoprotein lipase activation in vitro.", "content": "Effect of phospholipids on lipoprotein lipase activation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348316"}
{"pmid": "4348318", "title": "Lipid composition, Ca 2+  uptake and Ca 2+ -stimulated ATPase activity of sarcoplasmic reticulum of the cardiomyopathic hamster.", "content": "Lipid composition, Ca 2+  uptake and Ca 2+ -stimulated ATPase activity of sarcoplasmic reticulum of the cardiomyopathic hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348318"}
{"pmid": "4348319", "title": "Production of cholinesterase by Pseudomonas aeruginosa, its regulation by glucose and cyclic AMP and inhibition by antiserum.", "content": "Production of cholinesterase by Pseudomonas aeruginosa, its regulation by glucose and cyclic AMP and inhibition by antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348319"}
{"pmid": "4348320", "title": "Corticosteroid binding macromolecules in the nucleus and cytosol of rat thymus cells.", "content": "Corticosteroid binding macromolecules in the nucleus and cytosol of rat thymus cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348320"}
{"pmid": "4348322", "title": "Endogenous production of steroids by subcellular fractions from total rat testis and from isolated interstitial tissue and seminiferous tubules.", "content": "Endogenous production of steroids by subcellular fractions from total rat testis and from isolated interstitial tissue and seminiferous tubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348322"}
{"pmid": "4348323", "title": "Involvement of thiol enzymes in the lysosomal breakdown of native and denatured proteins.", "content": "Involvement of thiol enzymes in the lysosomal breakdown of native and denatured proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348323"}
{"pmid": "4348331", "title": "Phospholipids in artificially induced muscular dystrophy of calves.", "content": "Phospholipids in artificially induced muscular dystrophy of calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348331"}
{"pmid": "4348332", "title": "Submandibular duct lithiasis associated with a mixed salivary gland tumor. A case report.", "content": "Submandibular duct lithiasis associated with a mixed salivary gland tumor. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348332"}
{"pmid": "4348333", "title": "Proteinaceous precipitate in nodular (follicular) lymphomas.", "content": "Proteinaceous precipitate in nodular (follicular) lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348333"}
{"pmid": "4348334", "title": "Correlation of suspicious mammograms and x-rays of breast biopsies during surgery. Results in 60 cases.", "content": "Correlation of suspicious mammograms and x-rays of breast biopsies during surgery. Results in 60 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348334"}
{"pmid": "4348336", "title": "Carcinoma of the kidney in a 15-year-old boy. Unusual histologic features with formation of microvilli.", "content": "Carcinoma of the kidney in a 15-year-old boy. Unusual histologic features with formation of microvilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348336"}
{"pmid": "4348337", "title": "Primary thymic seminoma--a neoplasm ultrastructurally similar to testicular seminoma and distinct from epithelial thymoma.", "content": "Primary thymic seminoma--a neoplasm ultrastructurally similar to testicular seminoma and distinct from epithelial thymoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348337"}
{"pmid": "4348335", "title": "Sclerosing stromal tumors of the ovary.", "content": "Sclerosing stromal tumors of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348335"}
{"pmid": "4348339", "title": "Ultrastructure of the renal arterial bifurcation of rabbits.", "content": "Ultrastructure of the renal arterial bifurcation of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348339"}
{"pmid": "4348326", "title": "Isolation of oncornaviruses from chemically induced murine leukemias.", "content": "Isolation of oncornaviruses from chemically induced murine leukemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348326"}
{"pmid": "4348338", "title": "The intracellular site of surfactant synthesis. Autoradiographic studies on murine and avian lung explants.", "content": "The intracellular site of surfactant synthesis. Autoradiographic studies on murine and avian lung explants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348338"}
{"pmid": "4348329", "title": "NADH-cytochrome C reductase activity of antigen-stimulated macrophages.", "content": "NADH-cytochrome C reductase activity of antigen-stimulated macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348329"}
{"pmid": "4348340", "title": "Enzyme activity in the fluid of the human ovarian follicle.", "content": "Enzyme activity in the fluid of the human ovarian follicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348340"}
{"pmid": "4348342", "title": "Cinemicrography of pyrene perchlorate crystal formation by electrolysis.", "content": "Cinemicrography of pyrene perchlorate crystal formation by electrolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348342"}
{"pmid": "4348343", "title": "Renal sodium- and potassium-activated adenosine triphosphatase and sodium reabsorption in the hypothyroid rat.", "content": "Renal sodium- and potassium-activated adenosine triphosphatase and sodium reabsorption in the hypothyroid rat. The relationship between net tubular reabsorption of sodium and renal microsomal sodium- and potassium-activated adenosine triphosphatase (Na-K-ATPase) was evaluated in hypothyroid and hyperthyroid rats and in age-matched euthyroid controls. Tubular sodium reabsorption per gram of kidney was lower in thyroidectomized rats than in controls (186+/-14 vs. 246+/-12 mueq/min; P < 0.005) and was accompanied by a quantitatively similar reduction in Na-K-ATPase specific activity (49.4+/-2.4 vs. 65.8+/-2.3 mumol inorganic phosphate (P(t))/mg protein per h; P < 0.001). This decrement was present in both cortex and outer medulla, and was limited to Na-K-ATPase since other representative enzymes not involved in sodium transport (magnesium-dependent adenosine triphosphatase [Mg-ATPase], glucose-6-phosphatase, 5'-nucleotidase) remained unchanged or increased in the hypothyroid animals. Conversely, Na-K-ATPase rose when sodium reabsorption increased in euthyroid rats treated with triiodothyronine. Subsequent experiments were performed to determine to what extent the decrease in Na-K-ATPase is due to lack of thyroid hormone per se or to an adaptive response to decreased reabsorptive sodium load. Triiodothyronine in concentrations of 10(-12) to 10(-5) M had no effect in vitro on microsomal Na-K-ATPase of either thyroidectomized or euthyroid rats. When hypothyroid rats were uninephrectomized or treated with methylprednisolone, sodium reabsorption per gram kidney increased markedly and was similar to that of intact controls. Despite persistence of the hypothyroid state, Na-K-ATPase specific activity also increased to levels not significantly different from euthyroid animals. These data suggest that decreased tubular sodium transport is a major determinant of the reduction in renal Na-K-ATPase in thyroid deficiency since the latter can be reversed by increasing sodium reabsorption during continuing hypothyroidism. Furthermore, the modest sodium leak of hypothyroid animals does not appear to be due to decreased Na-K-ATPase since it was not corrected by uninephrectomy despite restoration of both cortical and medullary Na-K-ATPase activity to normal by this maneuver. The close correlation between net sodium reabsorption and Na-K-ATPase in all the experimental situations described here demonstrates that renal Na-K-ATPase changes adaptively in hyper- or hypothyroidism as it does in numerous situations in the normal animal, in accord with its postulated role in the active transport of sodium across the renal tubule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348343"}
{"pmid": "4348344", "title": "Comparative effects of angiotensin and ACTH on cyclic AMP and steroidogenesis in isolated bovine adrenal cells.", "content": "Comparative effects of angiotensin and ACTH on cyclic AMP and steroidogenesis in isolated bovine adrenal cells. The comparative effects of angiotensin II and adrenocorticotropic hormone (ACTH) on cyclic AMP and steroidogenesis were investigated employing isolated bovine adrenal cells from the zona fasciculata. Like ACTH, angiotensin produced a prompt increase in cyclic AMP which preceded the increase in corticosteroid production. Although this increase in cyclic AMP was small when compared to that induced by ACTH, it correlated with the amount of steroidogenesis. This observation is consistent with the view that cyclic AMP is the intracellular mediator of the steroidogenic action of angiotensin. Angiotensin acted synergistically with ACTH on cyclic AMP levels. This synergism was not explained by inhibition of phosphodiesterase activity. Unlike ACTH, angiotensin failed to stimulate adenylate cyclase in broken cell preparations. The observations suggest that more than one mechanism may be involved in effects of ACTH and angiotensin on cyclic AMP levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348344"}
{"pmid": "4348346", "title": "Evidence for stimulation of renal gluconeogenesis by catecholamines.", "content": "Evidence for stimulation of renal gluconeogenesis by catecholamines. Isoproterenol and norepinephrine (10(-4) M) significantly increased cyclic AMP formation and glucose production by the isolated tubules of the renal cortex of the rat. These effects were abolished by propranolol. Theophylline diminished the effects of the catecholamines on gluconeogenesis despite a marked augmentation in cyclic AMP concentration. In the absence of calcium ion in the incubation medium, isoproterenol stimulates cyclic AMP production, but has no effect on gluconeogenesis. It is concluded that catecholamines enhance gluconeogenesis in renal cortical tubules by the stimulation of beta adrenergic receptors. This effect is probably mediated through adenyl cyclase-cyclic AMP system and requires an adequate level of ATP and the presence of calcium ion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348346"}
{"pmid": "4348347", "title": "Tuberculosis--manifestations at uncommon sites.", "content": "Tuberculosis--manifestations at uncommon sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348347"}
{"pmid": "4348345", "title": "Effects of a false neurotransmitter, p-hydroxynorephedrine, on the function of adrenergic neurons in hypertensive patients.", "content": "Effects of a false neurotransmitter, p-hydroxynorephedrine, on the function of adrenergic neurons in hypertensive patients. Previous studies have shown that amphetamine and p-hydroxyamphetamine impair adrenergic transmission, and it has been suggested that this effect is mediated by an active metabolite, p-hydroxynorephedrine (PHN). Studies in experimental animals have shown that PHN can deplete and substitute for norepinephrine (NE) in the transmitter pool, thus meeting the criteria of a false neurotransmitter. The pharmacologic effects of PHN on adrenergic function and NE synthesis were studied in eight hypertensive patients and compared with placebo. Mean erect and supine blood pressure (BP) decreased 22/14 and 9/6 mm Hg, respectively, during PHN 600 mg daily. The post-Valsalva diastolic overshoot was abolished. The pressor sensitivity to tyramine decreased whereas the pressor response to NE was enhanced. A mild natriuresis occurred. The 24 h urinary excretion of catecholamines and catecholamine metabolites during the administration of PHN compared with placebo changed as follows: vanillylmandelic acid (VMA), 42% decrease; NE. 42% decrease; normetanephrine (NM), 400% increase: metanephrine, unchanged; dopamine, 40% decrease; while homovanillic acid was unchanged. The sum of VMA, NE, and NM decreased 23%. The posttreatment urinary excretion of PHN was biexponential with first and second phase half-lives of 13 and 55 h. respectively. The time of the second phase closely approximated the recovery of the changes in BP and excretion of VMA. No effects of PHN on the central nervous system were observed. These studies show that PHN acts peripherally to interfere with adrenergic function and NE synthesis in hypertensive patients with a resultant decrease in BP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348345"}
{"pmid": "4348348", "title": "Intestinal absorption of phosphate in the chick: effect of vitamin D and other parameters.", "content": "Intestinal absorption of phosphate in the chick: effect of vitamin D and other parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348348"}
{"pmid": "4348349", "title": "Influence of dietary protein and carbohydrate levels on liver enzyme activities in quail.", "content": "Influence of dietary protein and carbohydrate levels on liver enzyme activities in quail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348349"}
{"pmid": "4348351", "title": "Changes in the statistics of transmitter release during facilitation.", "content": "Changes in the statistics of transmitter release during facilitation. 1. The statistical nature of transmitter release during facilitation was studied at single synaptic sites by recording extracellular excitatory junctional potentials from the claw opener muscle in crayfish.2. At low temperatures, single quanta could be counted in the responses to nerve impulses. The distribution of the number of quanta observed (x) was most accurately described by assuming that x is a binomial random variable.3. A quantitative estimate was made of the effects of errors in counting quanta due to the simultaneous release of quanta and the release of quanta which were not individually detectable above the noise of the recording system. Such errors of observation cannot account for the deviation of quantal release from a Poisson distribution.4. Facilitated release occurred in the responses to the second of two closely following nerve impulses and in the responses to successive impulses in a tetanus. In both cases, the increase in the average number of quanta released (m) could be attributed entirely to an increase in the probability (p) that available quanta were released.5. The results can be interpreted most easily in terms of a model in which the maximum number of releasable quanta is limited by a finite number of discrete release sites within recording distance of the microelectrode. In this model, the binomial parameter n is an estimate of the number of these sites, and the statistical parameter p is a compound probability depending on the rate of re-occupying sites after a nerve discharge and the probability that an impulse activates an occupied site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348351"}
{"pmid": "4348350", "title": "Pre- and post-junctional effects of 1-fluoro-2,4-dinitrobenzene at the frog neuromuscular junction.", "content": "Pre- and post-junctional effects of 1-fluoro-2,4-dinitrobenzene at the frog neuromuscular junction. 1. FDNB increased by 60-90% the depolarization of the end-plate produced by applied carbachol in frog sciatic nerve-sartorius muscle preparations.2. In partially curarized preparations, FDNB (0.4 mM) increased the amplitude of the end-plate potential by a factor of 1.8.3. The quantal content of end-plate potentials was increased by FDNB (2 mM) as determined by the method of failures.4. After approximately 25-35 min, neuromuscular transmission was blocked by 0.4 mM-FDNB, as evidenced by abolition of neurally elicited end-plate potentials. At this stage miniature end-plate potentials could still be recorded, which indicates that the neuromuscular block was presynaptic.5. FDNB (0.4 mM) increased miniature end-plate potential frequency several hundred-fold when the Ringer solution contained normal calcium concentration (1.8 mM) or 0.45 mM calcium and 5.4 mM magnesium.6. During the first 60 min of exposure to 0.4 mM-FDNB there was a slight drop (4-6 mV) in resting potentials of muscle fibres. During this period directly initiated action potentials showed a marked decrease in the rate of repolarization and a small decrease in the amplitude and rate of rise.7. Using the technique of point voltage clamping in tetrodotoxin-treated muscles, it has been found that FDNB almost completely abolished the active increase in g(K) during stepwise depolarization of the nonjunctional muscle fibre membrane from -90 to 0 mV. The passive outward leakage current appeared unaffected by FDNB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348350"}
{"pmid": "4348354", "title": "Plasma aldosterone regulation in anephric man.", "content": "Plasma aldosterone regulation in anephric man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348354"}
{"pmid": "4348356", "title": "Influence of lymphography in determining extent of disease in patients with lymphoma.", "content": "Influence of lymphography in determining extent of disease in patients with lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348356"}
{"pmid": "4348358", "title": "Effect of Rho on transcription of bacterial operons.", "content": "Effect of Rho on transcription of bacterial operons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348358"}
{"pmid": "4348359", "title": "Human embryonic lung cells abortively infected with Herpes virus hominis type 2 show some properties of cell transformation.", "content": "Human embryonic lung cells abortively infected with Herpes virus hominis type 2 show some properties of cell transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348359"}
{"pmid": "4348360", "title": "Mechanotransduction in insect neurones.", "content": "Mechanotransduction in insect neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348360"}
{"pmid": "4348361", "title": "Skin as aid to neurology.", "content": "Skin as aid to neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348361"}
{"pmid": "4348362", "title": "Seventeenth Bowditch lecture. Neural and humoral factors in the temporal organization of behavior.", "content": "Seventeenth Bowditch lecture. Neural and humoral factors in the temporal organization of behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348362"}
{"pmid": "4348364", "title": "Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine 8-AII.", "content": "Stimulation of splenic prostaglandin release by angiotensin and specific inhibition by cysteine 8-AII.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348364"}
{"pmid": "4348367", "title": "Steroids and related products. 38. 11-Aza steroids. 3. The synthesis of 11-aza 9 -steroids. I.", "content": "Steroids and related products. 38. 11-Aza steroids. 3. The synthesis of 11-aza 9 -steroids. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348367"}
{"pmid": "4348368", "title": "An androgen binding protein in the testis cytosol fraction of adult rats. Comparison with the androgen binding protein in the epididymis.", "content": "An androgen binding protein in the testis cytosol fraction of adult rats. Comparison with the androgen binding protein in the epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348368"}
{"pmid": "4348369", "title": "Steroid modifications. II. The effect of ruthenium tetroxide on several aromatic steroids.", "content": "Steroid modifications. II. The effect of ruthenium tetroxide on several aromatic steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348369"}
{"pmid": "4348357", "title": "Crystalloid intracytoplasmic inclusions in lymphocytes of a patient with chronic lymphocytic leukemia.", "content": "Crystalloid intracytoplasmic inclusions in lymphocytes of a patient with chronic lymphocytic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348357"}
{"pmid": "4348363", "title": "The diagnostic significance of enzyme estimations in clinical medicine.", "content": "The diagnostic significance of enzyme estimations in clinical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348363"}
{"pmid": "4348376", "title": "Recognition of leprosy.", "content": "Recognition of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348376"}
{"pmid": "4348378", "title": "Ultrastructure of the pars distalis of the lizard Anolis carolinensis with special reference to the identification of the gonadotropic cell.", "content": "Ultrastructure of the pars distalis of the lizard Anolis carolinensis with special reference to the identification of the gonadotropic cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348378"}
{"pmid": "4348379", "title": "The ultrastructure of the accessory sex organs of the male rat. I. Normal structure.", "content": "The ultrastructure of the accessory sex organs of the male rat. I. Normal structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348379"}
{"pmid": "4348380", "title": "Ultrastructure of the rat neural lobe during recovery from hypertonic saline treatment.", "content": "Ultrastructure of the rat neural lobe during recovery from hypertonic saline treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348380"}
{"pmid": "4348382", "title": "Purification and properties of nucleases from pig pituitary gland.", "content": "Purification and properties of nucleases from pig pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348382"}
{"pmid": "4348383", "title": "Localization of oestradiol receptors in the rat hypothalamus.", "content": "Localization of oestradiol receptors in the rat hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348383"}
{"pmid": "4348384", "title": "Compartmental arrangement of steroids formed from (1- 14 C)acetate by rat adrenal zona glomerulosa and the effect of corticotrophin.", "content": "Compartmental arrangement of steroids formed from (1- 14 C)acetate by rat adrenal zona glomerulosa and the effect of corticotrophin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348384"}
{"pmid": "4348385", "title": "The biosynthesis and secretion of aldosterone by the rat adrenal zona glomerulosa, and the significance of the compartmental arrangement of steroids.", "content": "The biosynthesis and secretion of aldosterone by the rat adrenal zona glomerulosa, and the significance of the compartmental arrangement of steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348385"}
{"pmid": "4348386", "title": "Early variations of plasma cortisol after pulse intravenous injection of dibutyryl cyclic adenosine 3',5'-monophosphate in normal subjects.", "content": "Early variations of plasma cortisol after pulse intravenous injection of dibutyryl cyclic adenosine 3',5'-monophosphate in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348386"}
{"pmid": "4348387", "title": "Effects of gonadotrophins and cyclic 3',5'-AMP on in vitro incorporation of ( 3 H)uridine into RNA of the prepubertal rat ovary.", "content": "Effects of gonadotrophins and cyclic 3',5'-AMP on in vitro incorporation of ( 3 H)uridine into RNA of the prepubertal rat ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348387"}
{"pmid": "4348388", "title": "Managing the menopause.", "content": "Managing the menopause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348388"}
{"pmid": "4348389", "title": "Pathogenicity of low-virulence strains of two canine adenovirus types.", "content": "Pathogenicity of low-virulence strains of two canine adenovirus types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348389"}
{"pmid": "4348390", "title": "Chronic superficial keratitis in dogs: negative results of isolation procedures for Chlamydia.", "content": "Chronic superficial keratitis in dogs: negative results of isolation procedures for Chlamydia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348390"}
{"pmid": "4348391", "title": "Isolation of parainfluenza type 3 virus from the prepuce of bulls in Northern Queensland.", "content": "Isolation of parainfluenza type 3 virus from the prepuce of bulls in Northern Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348391"}
{"pmid": "4348392", "title": "The influence of age and barbital treatment on the content of cytochrome P-450 and b 5  and on the activity of glucose-6-phosphatase in microsomes of the rat liver and kidney.", "content": "The influence of age and barbital treatment on the content of cytochrome P-450 and b 5  and on the activity of glucose-6-phosphatase in microsomes of the rat liver and kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348392"}
{"pmid": "4348395", "title": "Cell-bound antiglial immunity in patients with malignant tumors of the brain.", "content": "Cell-bound antiglial immunity in patients with malignant tumors of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348395"}
{"pmid": "4348394", "title": "Adenosine 3',5'-cyclic monophosphate phosphodiesterase in guinea-pig lung--properties and effect of adrenergic drugs.", "content": "Adenosine 3',5'-cyclic monophosphate phosphodiesterase in guinea-pig lung--properties and effect of adrenergic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348394"}
{"pmid": "4348393", "title": "Activation of a specific human plasma kininogenase with trypsin and plasmin.", "content": "Activation of a specific human plasma kininogenase with trypsin and plasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348393"}
{"pmid": "4348396", "title": "Regulatory role of reducing-equivalent transfer from substrate to oxygen in the hepatic metabolism of glycerol and sorbitol.", "content": "Regulatory role of reducing-equivalent transfer from substrate to oxygen in the hepatic metabolism of glycerol and sorbitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348396"}
{"pmid": "4348397", "title": "Differences in nucleotide sequences of ribosomal RNA between the liver and a hepatoma of C3H-He mice.", "content": "Differences in nucleotide sequences of ribosomal RNA between the liver and a hepatoma of C3H-He mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348397"}
{"pmid": "4348398", "title": "The effects of thioketo substitution upon uracil-adenine interactions in polyribonucleotides. Synthesis and properties of poly (2-thiouridylic acid) and poly(2,4-dithiouridylic acid).", "content": "The effects of thioketo substitution upon uracil-adenine interactions in polyribonucleotides. Synthesis and properties of poly (2-thiouridylic acid) and poly(2,4-dithiouridylic acid).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348398"}
{"pmid": "4348399", "title": "The induction of translocators for di- and tricarboxylic-acid anions in Azotobacter vinelandii.", "content": "The induction of translocators for di- and tricarboxylic-acid anions in Azotobacter vinelandii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348399"}
{"pmid": "4348400", "title": "The role of lysosomal enzymes in skeletal tissues.", "content": "The role of lysosomal enzymes in skeletal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348400"}
{"pmid": "4348401", "title": "Estimation of virus-neutralizing antibody in microplates.", "content": "Estimation of virus-neutralizing antibody in microplates. A simple and rapid method for the titration of virus-neutralizing antibody is described. The micro-apparatus and reagents are readily available from commercial sources. Results are included from selected cases which illustrate various conditions of immune status and response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348401"}
{"pmid": "4348402", "title": "FL 1060: a new beta-lactam antibiotic with novel properties.", "content": "FL 1060: a new beta-lactam antibiotic with novel properties. The effect of FL 1060, a newly described beta-lactam antibiotic, on three strains of Escherichia coli was studied. The agent showed extraordinarily high activity as judged by conventional titrations, but inoculum size, osmolality of the medium, and length of the incubation period were all found to have a marked effect on the result. Continuous turbidimetric monitoring and microscopical observation of cultures of E. coli exposed to FL 1060 showed the effect of the antibiotic to have many novel features. Exposed bacterial rods converted to spherical forms, but in a different manner from that of classical penicillin-mediated transformation. Furthermore, although FL 1060 was bactericidal for the majority of the bacterial population, a fraction not only survived its lethal action but grew in high concentrations of the agent thereby producing a phenotypically resistant population which nonetheless continued to show characteristic morphological deformities. Possible reasons for this anomalous behaviour are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348402"}
{"pmid": "4348403", "title": "Frequency of intraendothelial 'virus-like' particles: an electron microscopy study of 376 human renal biopsies.", "content": "Frequency of intraendothelial 'virus-like' particles: an electron microscopy study of 376 human renal biopsies. Intraendothelial ;virus-like' particles were found in all cases requiring a renal biopsy: in 89% of patients with systemic lupus erythematosus (SLE), in 73% of those receiving renal transplants more than one year before, and in 24.5% of all other renal biopsies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348403"}
{"pmid": "4348405", "title": "Cardiac mitochondrial activity in acute and chronic cyanosis.", "content": "Cardiac mitochondrial activity in acute and chronic cyanosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348405"}
{"pmid": "4348404", "title": "Serial nitroblue tetrazolium tests in the management of infection.", "content": "Serial nitroblue tetrazolium tests in the management of infection. Two cases are described in which extensive use was made of the nitroblue tetrazolium (NBT) test. In the first case the advantages of using this technique to diagnose and control infection is shown; in the second the considerable advantage of the speed of the technique. In both of these cases the test made a material contribution to the management of the patient, and it is concluded that the test brings bacteriological control of the patient within the immediate clinical area, thus overcoming one of the principal disadvantages of the classical bacteriological methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348404"}
{"pmid": "4348406", "title": "Relationship of cyclic AMP to secretin stimulation of the pancreas.", "content": "Relationship of cyclic AMP to secretin stimulation of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348406"}
{"pmid": "4348408", "title": "Fatal measles infection in children with leukemia.", "content": "Fatal measles infection in children with leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348408"}
{"pmid": "4348410", "title": "Arsenic intoxication from well water in the United States.", "content": "Arsenic intoxication from well water in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348410"}
{"pmid": "4348409", "title": "Effects of 3',5'-cyclic nucleotides on adrenocortical cells of hypophysectomized rats. A stereologic and autoradiographic study.", "content": "Effects of 3',5'-cyclic nucleotides on adrenocortical cells of hypophysectomized rats. A stereologic and autoradiographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348409"}
{"pmid": "4348412", "title": "Neuropathy of long-distance running.", "content": "Neuropathy of long-distance running.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348412"}
{"pmid": "4348411", "title": "Adrenocortical response to ACTH in Addison's disease.", "content": "Adrenocortical response to ACTH in Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348411"}
{"pmid": "4348413", "title": "Intranuclear inclusion bodies.", "content": "Intranuclear inclusion bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348413"}
{"pmid": "4348414", "title": "The amino-acid sequence of cytochrome c from Euglena gracilis.", "content": "The amino-acid sequence of cytochrome c from Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348414"}
{"pmid": "4348415", "title": "The properties and amino-acid sequence of cytochrome c from Euglena gracilis.", "content": "The properties and amino-acid sequence of cytochrome c from Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348415"}
{"pmid": "4348416", "title": "A preliminary investigation of the swine vesicular disease epidemic in Britain.", "content": "A preliminary investigation of the swine vesicular disease epidemic in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348416"}
{"pmid": "4348417", "title": "Electron microscopic study of liver lesions, especially hepatic megalocytosis induced by 1-(4-dimethylamino-benzylidene)-indene (DABI) in mice.", "content": "Electron microscopic study of liver lesions, especially hepatic megalocytosis induced by 1-(4-dimethylamino-benzylidene)-indene (DABI) in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348417"}
{"pmid": "4348420", "title": "The role of reticular formation in integration.", "content": "The role of reticular formation in integration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348420"}
{"pmid": "4348421", "title": "Studies on the tardigrades. 3. Fine structure of the esophagus of Milnesium tardigradum Doyère.", "content": "Studies on the tardigrades. 3. Fine structure of the esophagus of Milnesium tardigradum Doyère.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348421"}
{"pmid": "4348422", "title": "The digital pads of the tree frog, Hyla cinerea. I. The epidermis.", "content": "The digital pads of the tree frog, Hyla cinerea. I. The epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348422"}
{"pmid": "4348423", "title": "Treatment of amoebic liver abscess and amoebic dysentery with metronidazole.", "content": "Treatment of amoebic liver abscess and amoebic dysentery with metronidazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348423"}
{"pmid": "4348424", "title": "Australia antigen in liver disease in Zambia.", "content": "Australia antigen in liver disease in Zambia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348424"}
{"pmid": "4348429", "title": "A new method for measuring ultrasonic velocity.", "content": "A new method for measuring ultrasonic velocity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348429"}
{"pmid": "4348428", "title": "Sterol and phospholipid biosynthesis in phytohemagglutinin stimulated human lymphocytes.", "content": "Sterol and phospholipid biosynthesis in phytohemagglutinin stimulated human lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348428"}
{"pmid": "4348430", "title": "Pseudomonas cytochrome c peroxidase. V. Absorption spectra of the enzyme and of its compounds with ligands. Inhibition of the enzyme by cyanide and azide.", "content": "Pseudomonas cytochrome c peroxidase. V. Absorption spectra of the enzyme and of its compounds with ligands. Inhibition of the enzyme by cyanide and azide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348430"}
{"pmid": "4348431", "title": "Recurring digital fibrous tumour of childhood. Case report and survey.", "content": "Recurring digital fibrous tumour of childhood. Case report and survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348431"}
{"pmid": "4348434", "title": "Fine structure of human pituitary adenoma.", "content": "Fine structure of human pituitary adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348434"}
{"pmid": "4348435", "title": "Encephalomyocarditis virus (E variant) in mice. Pancreatic changes.", "content": "Encephalomyocarditis virus (E variant) in mice. Pancreatic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348435"}
{"pmid": "4348436", "title": "Nuclear DNA in salivary gland tumors. II. Adenocystic carcinomas.", "content": "Nuclear DNA in salivary gland tumors. II. Adenocystic carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348436"}
{"pmid": "4348437", "title": "Treatment of vaginal trichomoniasis with a new anti-protozoal compound ( -chloromethyl-2-methyl-5-nitro-1-imidazole-ethanol).", "content": "Treatment of vaginal trichomoniasis with a new anti-protozoal compound ( -chloromethyl-2-methyl-5-nitro-1-imidazole-ethanol).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348437"}
{"pmid": "4348438", "title": "Delayed cutaneous metastases of mucus-producing cell carcinoma of the stomach.", "content": "Delayed cutaneous metastases of mucus-producing cell carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348438"}
{"pmid": "4348439", "title": "Conformational studies on lipoamide dehydrogenase from pig heart. I. Interconversion of dissociable and non-dissociable forms.", "content": "Conformational studies on lipoamide dehydrogenase from pig heart. I. Interconversion of dissociable and non-dissociable forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348439"}
{"pmid": "4348440", "title": "Conformational studies on lipoamide dehydrogenase from pig heart. 2. Spectroscopic studies on the apoenzyme and the monomeric and dimeric forms.", "content": "Conformational studies on lipoamide dehydrogenase from pig heart. 2. Spectroscopic studies on the apoenzyme and the monomeric and dimeric forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348440"}
{"pmid": "4348441", "title": "Conformational studies on lipoamide dehydrogenase from pig heart. 3. The binding of sodium dodecylsulphate.", "content": "Conformational studies on lipoamide dehydrogenase from pig heart. 3. The binding of sodium dodecylsulphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348441"}
{"pmid": "4348442", "title": "Conformational studies on lipoamide dehydrogenase from pig heart. 4. The binding of NAD +  to non-equivalent sites.", "content": "Conformational studies on lipoamide dehydrogenase from pig heart. 4. The binding of NAD +  to non-equivalent sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348442"}
{"pmid": "4348444", "title": "Slow conformational changes of the inorganic pyrophosphatase from bakers' yeast induced by divalent metal ions.", "content": "Slow conformational changes of the inorganic pyrophosphatase from bakers' yeast induced by divalent metal ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348444"}
{"pmid": "4348443", "title": "The initiation of protein synthesis directed by the RNA from encephalomyocarditis virus.", "content": "The initiation of protein synthesis directed by the RNA from encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348443"}
{"pmid": "4348446", "title": "Suppression of testicular androgen synthesis in the rat by ethylene dimethanesulphonate.", "content": "Suppression of testicular androgen synthesis in the rat by ethylene dimethanesulphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348446"}
{"pmid": "4348445", "title": "Binding of ligands to the inorganic pyrophosphatase of bakers' yeast.", "content": "Binding of ligands to the inorganic pyrophosphatase of bakers' yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348445"}
{"pmid": "4348447", "title": "Antagonists of trophic hormones.", "content": "Antagonists of trophic hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348447"}
{"pmid": "4348448", "title": "Temperature studies of the hand and its claw deformities due to peripheral nerve paralysis in leprosy.", "content": "Temperature studies of the hand and its claw deformities due to peripheral nerve paralysis in leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348448"}
{"pmid": "4348449", "title": "Sarcoma of tendon sheath.", "content": "Sarcoma of tendon sheath.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348449"}
{"pmid": "4348450", "title": "Influence of time factor on the restoration of adrenal weight and cortical functions in hypophysectomized rats.", "content": "Influence of time factor on the restoration of adrenal weight and cortical functions in hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348450"}
{"pmid": "4348451", "title": "Lipolytic enzymes and the action of ACTH on lipid metabolism in rat adrenals.", "content": "Lipolytic enzymes and the action of ACTH on lipid metabolism in rat adrenals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348451"}
{"pmid": "4348452", "title": "Viral-host relationships in chronic diseases of man.", "content": "Viral-host relationships in chronic diseases of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348452"}
{"pmid": "4348453", "title": "On the aetiology of whooping cough.", "content": "On the aetiology of whooping cough. The results of routine bacterial and viral studies on 483 patients with whooping cough, investigated at one hospital over a five year period are presented. The possible role of respiratory viruses in the aetiology of the disease is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348453"}
{"pmid": "4348454", "title": "Social class and infectious mononucleosis.", "content": "Social class and infectious mononucleosis. The socio-economic status of 80 patients with infectious mononucleosis was compared with the socio-economic distribution of the general population in the same area of south-west London. An excess incidence of infectious mononucleosis was observed among subjects from upper socio-economic groups. A possible relationship between this observation and the epidemiology of the Epstein-Barr virus is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348454"}
{"pmid": "4348455", "title": "Epstein-Barr virus antibody in cases and contacts of infectious mononucleosis; a family study.", "content": "Epstein-Barr virus antibody in cases and contacts of infectious mononucleosis; a family study. Serological investigations were carried out on 147 patients with Paul-Bunnell positive infectious mononucleosis (IM) from the general population. All possessed antibody to the Epstein-Barr virus (EBV) and 63% showed serological evidence of recent infection. Contacts of 132 patients, 306 in all, were followed serologically; within 6 months of the index cases' illness twenty one contacts developed evidence of EBV infection or re-infection and of these five developed overt IM. The secondary attack rate of EBV infection among susceptible contacts was at least 19%; the corresponding figure for clinically apparent IM was 6%. EBV antibody prevalence among patients' siblings was significantly lower than among age-matched controls, suggesting that cases of IM come from families with a lower than normal previous experience of the virus. Of thirteen patients with persistently Paul-Bunnell negative ;glandular fever' four had serological evidence of recent EBV infection and two had probable cytomegalovirus mononucleosis. Recent EBV infection may have been associated with the illnesses of five of the remaining patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348455"}
{"pmid": "4348457", "title": "An analog computer study of fast, isolated movements.", "content": "An analog computer study of fast, isolated movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348457"}
{"pmid": "4348456", "title": "Pertussis antibodies in the sera of children exposed to Bordetella pertussis by vaccination or infection.", "content": "Pertussis antibodies in the sera of children exposed to Bordetella pertussis by vaccination or infection. Low agglutinin titres to pertussis suspensions were found in 99% of sera from a group comprising healthy adults and non-vaccinated, non-infected infants of 1-6 months of age. These are attributable to agglutinins to heat-stable antigens and/or heat labile agglutinogen 1, and cross-absorption tests must be done on the sera in order to distinguish between the two. Agglutinins to agglutinogens 2 and 3 were found in only about 20% of adult sera. Bactericidal antibody was low in titre or absent in all sera from non-exposed individuals.Raised bactericidal antibody titres and the presence of agglutinins 2 and 3 were attributed to exposure to Bordetella pertussis antigens, either as vaccine or as infection. The variation, amongst both vaccinated and infected children, was very great. A vaccinated child who became ill responded to the infection in much the same way as a non-vaccinated child. We were unable to relate the immunity of the child to the titres either of agglutinins or of the bactericidal antibody.The protective ability of sera from vaccinated or infected children measured in mice against small, lethal brain infections was also unrelated to the state of immunity in the children, but this protective ability was correlated with the complement-mediated bactericidal antibody titres of the sera.The distribution of agglutinins, bactericidal antibody, and anti-haemagglutinin in serum IgG and IgM was different in vaccinated and infected children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348456"}
{"pmid": "4348458", "title": "Homology between Epstein-Barr virus DNA and viral DNA from Burkitt's lymphoma and nasopharyngeal carcinoma determined by DNA-DNA reassociation kinetics.", "content": "Homology between Epstein-Barr virus DNA and viral DNA from Burkitt's lymphoma and nasopharyngeal carcinoma determined by DNA-DNA reassociation kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348458"}
{"pmid": "4348459", "title": "Cell fusion induced by a virus within the zona pellucida of mouse eggs.", "content": "Cell fusion induced by a virus within the zona pellucida of mouse eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348459"}
{"pmid": "4348460", "title": "Effect of magnesium on horizontal cell activity in the skate retina.", "content": "Effect of magnesium on horizontal cell activity in the skate retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348460"}
{"pmid": "4348461", "title": "Differentiation between necrotic ulcerative gingivitis and primary herpetic gingivostomatitis.", "content": "Differentiation between necrotic ulcerative gingivitis and primary herpetic gingivostomatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348461"}
{"pmid": "4348463", "title": "1 -Hydroxy derivative of vitamin D 3 : a highly potent analog of 1 ,25-dihydroxyvitamin D 3 .", "content": "1 -Hydroxy derivative of vitamin D 3 : a highly potent analog of 1 ,25-dihydroxyvitamin D 3 . The 1alpha-hydroxy derivative of vitamin D(3) has been chemically synthesized and tested for its biological activity. This analog has comparable biological activity on a weight basis to 1,25-dihydroxyvitamin D(3) in the stimulation of intestinal calcium transport and bone calcium mobilization in normnal and anephric rats. Because the 1alpha-hydroxy derivative is synthesized from cholesterol, it is easier and less expensive to prepare than 1alpha,25-dihydroxy derivative, making it attractive as a drug in the treatment of renal osteodystrophy and hypopara-thyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348463"}
{"pmid": "4348464", "title": "Natural abundance carbon-13 nuclear magnetic resonance spectra of human serum lipoproteins.", "content": "Natural abundance carbon-13 nuclear magnetic resonance spectra of human serum lipoproteins. Human serum lipoproteins have been studied by Fourier transform nuclear magnetic resonance of carbon-13 in natural abundance. Spectra of highdensity, low-density, and very-low-density lipoproteins were recorded and partly assigned. The prominent features of these spectra reflect the qualitative and quantitative composition of the lipid moiety of these complexes. The results suggest that carbon-13 nuclear magnetic resonance will be a useful technique for studies of the structural and dynamic parameters of lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348464"}
{"pmid": "4348466", "title": "Extraction of equine infectious anemia immunodiffusion antigen with the aid of the chaotropic agent, thiocyanate.", "content": "Extraction of equine infectious anemia immunodiffusion antigen with the aid of the chaotropic agent, thiocyanate. Immunodiffusion antigen from spleens of horses infected with equine infectious anemia virus was prepared by methods employing freeze-thaw cycles and thiocyanate treatment. Thiocyanate (0.5 M) permitted the recovery of the greatest amount of antigen. Furthermore, it was most effective for recovery of immunodiffusion antigen from spleens which yielded unsatisfactory concentrations of antigen by the conventional freeze-thaw or water-extraction methods. The reactivity of the antigen did not appear to be affected by this chemical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348466"}
{"pmid": "4348467", "title": "Virus susceptibility of a new simian cell line of fetal origin.", "content": "Virus susceptibility of a new simian cell line of fetal origin. The cultivation and characterization of a cell line derived from the foreskin of a fetal, rhesus monkey (rhfs2) are described. This cell line has proven satisfactory for isolation and assay of a variety of viral agents of human and simian origin. Virus titrations performed on foreskin cells yielded titers comparable to, or higher than, those obtained in rhesus monkey kidney cells (LLC-MK2). Replicate isolation attempts in our laboratory from simian clinical specimens have proven rhfs2 superior to LLC-MK2 for ease of detection and frequency of isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348467"}
{"pmid": "4348468", "title": "Rapid method to determine labeling specificity of radioactive enteroviruses.", "content": "Rapid method to determine labeling specificity of radioactive enteroviruses. The specificity of labeling enteroviruses with (32)P-labeled NaH(2)PO(4) or (14)C-leucine can be determined by comparing the percent adsorption of infective particles and radioactivity to membrane (Millipore) filters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348468"}
{"pmid": "4348469", "title": "Evaluation of two types of infectious mononucleosis antigen slides by the indirect fluorescent-antibody technique.", "content": "Evaluation of two types of infectious mononucleosis antigen slides by the indirect fluorescent-antibody technique. The efficiency of two types of antigen slides was compared by using the indirect fluorescent-antibody technique. Fifty sera from infectious mononucleosis patients were tested concurrently on the two sets of slides for antibody to Epstein-Barr virus. The indirect fluorescent-antibody serum titer readings from the epoxy slides were either equal to or twofold higher than those from the cover slip slides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348469"}
{"pmid": "4348470", "title": "Neuraminidase induced loss in the transplantability of murine leukaemia L 1210, induction of immunoprotection and the transfer of induced immunity to normal DBA-2 mice by serum and peritoneal cells.", "content": "Neuraminidase induced loss in the transplantability of murine leukaemia L 1210, induction of immunoprotection and the transfer of induced immunity to normal DBA-2 mice by serum and peritoneal cells. Leukaemia L 1210 cells preincubated in vitro with neuraminidase preparations derived either from Vibrio cholerae (VCN) or Clostridium perfringens (CPN) lost their i.p. transplantability for normal DBA/2 mice. This loss of transplantability could not be observed when the enzyme treated cells were implanted in mice whose immune status was suppressed by prior cyclophosphamide treatment. Mice receiving i.p. implants of enzyme treated leukaemia cells developed immunity to subsequent i.p. challenge with untreated L 1210 cells but not to a challenge with Ehrlich ascites tumour cells. The magnitude of immune response evoked by L 1210 cells preincubated with 250 u/ml of VCN or 35 μg/ml of CPN for 60 minutes was of relatively low level when compared with the immunity induced by leukaemia cells preincubated with 50 u/ml of VCN or 15 μg/ml of CPN for 30 or 60 minutes. Evidence is presented to show that the induced immunity can be transferred passively with the serum and with the peritoneal cells from the mice implanted with VCN treated L 1210 cells to normal DBA/2 mice. The significance of the neuraminidase induced increase in the immunogenicity of treated tumour cells is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348470"}
{"pmid": "4348473", "title": "Glomus tumours.", "content": "Glomus tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348473"}
{"pmid": "4348471", "title": "Human peripheral lung tumours: light and electron microscopic correlation.", "content": "Human peripheral lung tumours: light and electron microscopic correlation. Thirteen human peripheral lung tumours have been studied in both light and electron microscopy. They were classified as epidermoid carcinoma, mucus-secreting cell adenocarcinoma, and alveolar cell adenocarcinoma, the latter made up of granular pneumocytes. Alveolar cell cancer, as defined by ultrastructural features, could assume different gross histological patterns in light microscopy, and therefore electron microscopy is required for its identification.Since neither squamous nor mucous metaplasia was observed in any alveolar cell tumour, it is tentatively suggested that all peripheral lung tumours which lack these features may be derived from granular pneumocytes, irrespective of whether they appear to be adenocarcinomata or large cell carcinomata when examined by light microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348471"}
{"pmid": "4348472", "title": "Glioblastoma multiforme: a controlled trial to assess the value of specific active immunotherapy in patients treated by radical surgery and radiotherapy.", "content": "Glioblastoma multiforme: a controlled trial to assess the value of specific active immunotherapy in patients treated by radical surgery and radiotherapy. The results are reported of a randomized prospective clinical trial carried out to assess the value of specific active immunotherapy using irradiated autologous tumour cells in patients with glioblastoma multiforme treated by radical surgery and post-operative irradiation. The results in 62 patients show no statistically significant difference in survival between the group receiving adjuvant autologous tumour cells and those treated with surgery and radiotherapy alone. All 27 patients receiving tumour cells were dead at 30 months, whereas 7 of the 35 controls were alive at this time. The results were considered sufficiently discouraging to abandon the trial at this stage on the grounds that there was sufficient evidence in this study that the administration of irradiated autologous cells was of no benefit to patients with high grade astrocytomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348472"}
{"pmid": "4348474", "title": "Early diagnosis of nephroblastoma.", "content": "Early diagnosis of nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348474"}
{"pmid": "4348476", "title": "Persistent haemagglutination for infectious mononucleosis in rheumatoid arthritis.", "content": "Persistent haemagglutination for infectious mononucleosis in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348476"}
{"pmid": "4348477", "title": "Infection with E.B. virus.", "content": "Infection with E.B. virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348477"}
{"pmid": "4348475", "title": "Comparative trial of P1496, a new non-steroidal oestrogen analogue.", "content": "Comparative trial of P1496, a new non-steroidal oestrogen analogue. The results are reported of a preliminary trial of P1496, a new non-steroidal oestrogen analogue, compared with a conjugated equine oestrogen and a placebo. The oestrogenicity of both substances was well substantiated by vaginal epithelial maturation indices. P1496 was superior to conjugated equine oestrogen in producing a significant reduction of plasma calcium levels and a possible reduction in serum cholesterol. Conjugated oestrogen caused slightly more nausea than P1496 but there were no notable side effects from either drug. P1496 is considered to be at least as effective an oestrogenic substance as conjugated oestrogen and worthy of further therapeutic evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348475"}
{"pmid": "4348479", "title": "Glomus tumours.", "content": "Glomus tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348479"}
{"pmid": "4348478", "title": "Recovery of adrenal function after substitution of beclomethasone dipropionate for oral corticosteroids.", "content": "Recovery of adrenal function after substitution of beclomethasone dipropionate for oral corticosteroids. Of 16 steroid-dependent asthmatic patients oral treatment has been discontinued in six and reduced in four after the introduction of beclomethasone dipropionate. Substitution of inhaled beclomethasone for oral steroids was unsuccessful in the remaining six patients. Serial adrenal function studies in the patients whose oral treatment was discontinued showed progressive recovery, and five out of six had a normal response to tetracosactrin stimulation after two months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348478"}
{"pmid": "4348480", "title": "Herpes simplex and zoster.", "content": "Herpes simplex and zoster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348480"}
{"pmid": "4348483", "title": "Determination of IgG heavy chains by electroimmunodiffusion in the nanogram range: simultaneous application to serum and CSF of neurological patients.", "content": "Determination of IgG heavy chains by electroimmunodiffusion in the nanogram range: simultaneous application to serum and CSF of neurological patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348483"}
{"pmid": "4348484", "title": "Plasma lipids in patients with chronic renal failure.", "content": "Plasma lipids in patients with chronic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348484"}
{"pmid": "4348485", "title": "The diagnostic value of thrombocytic glucose-6-phosphatase in patients with von Gierke's disease and its heterozygotes.", "content": "The diagnostic value of thrombocytic glucose-6-phosphatase in patients with von Gierke's disease and its heterozygotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348485"}
{"pmid": "4348487", "title": "Histochemical and histological studies of rat myocardium following mechanical compression.", "content": "Histochemical and histological studies of rat myocardium following mechanical compression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348487"}
{"pmid": "4348488", "title": "Crystalloid inclusions in mitochondria of renal tubules.", "content": "Crystalloid inclusions in mitochondria of renal tubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348488"}
{"pmid": "4348491", "title": "Electron spin resonance of spin labels in organic inclusion crystals. Models for anisotropic motion in biological membranes.", "content": "Electron spin resonance of spin labels in organic inclusion crystals. Models for anisotropic motion in biological membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348491"}
{"pmid": "4348490", "title": "Growth and its regulation in the healthy child.", "content": "Growth and its regulation in the healthy child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348490"}
{"pmid": "4348492", "title": "A theoretical model for the effects of local nonpolar heme environments on the redox potentials in cytochromes.", "content": "A theoretical model for the effects of local nonpolar heme environments on the redox potentials in cytochromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348492"}
{"pmid": "4348493", "title": "A convenient synthesis of 1 -hydroxy-vitamin D 3 .", "content": "A convenient synthesis of 1 -hydroxy-vitamin D 3 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348493"}
{"pmid": "4348494", "title": "Hindlimb muscle fiber populations of five mammals.", "content": "Hindlimb muscle fiber populations of five mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348494"}
{"pmid": "4348495", "title": "Different patterns of neurologic involvement with herpes simplex virus types 1 and 2: isolation of herpes simplex virus type 2 from the buffy coat of two adults with meningitis.", "content": "Different patterns of neurologic involvement with herpes simplex virus types 1 and 2: isolation of herpes simplex virus type 2 from the buffy coat of two adults with meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348495"}
{"pmid": "4348496", "title": "The limited effect of nasal interferon induced by rhinovirus and a topical chemical inducer on the course of infection.", "content": "The limited effect of nasal interferon induced by rhinovirus and a topical chemical inducer on the course of infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348496"}
{"pmid": "4348497", "title": "Inhibition of oral shedding of herpes simplex virus by cytosine arabinoside.", "content": "Inhibition of oral shedding of herpes simplex virus by cytosine arabinoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348497"}
{"pmid": "4348498", "title": "Impaired production of interferon in lymphocytes from immunosuppressed patients.", "content": "Impaired production of interferon in lymphocytes from immunosuppressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348498"}
{"pmid": "4348500", "title": "Adenoid cystic carcinoma of the ear canal.", "content": "Adenoid cystic carcinoma of the ear canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348500"}
{"pmid": "4348499", "title": "Leukocyte-transforming agent: prolonged excretion by patients with mononucleosis and excretion by normal individuals.", "content": "Leukocyte-transforming agent: prolonged excretion by patients with mononucleosis and excretion by normal individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348499"}
{"pmid": "4348502", "title": "Survey for antibodies to canine viruses in selected wild mammals.", "content": "Survey for antibodies to canine viruses in selected wild mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348502"}
{"pmid": "4348501", "title": "Lipid metabolism in pregnancy. I. Changes in lipoprotein triglyceride and cholesterol in normal pregnancy and the effects of diabetes mellitus.", "content": "Lipid metabolism in pregnancy. I. Changes in lipoprotein triglyceride and cholesterol in normal pregnancy and the effects of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348501"}
{"pmid": "4348503", "title": "Ultrasonic visualization in determination of tumor growth rate.", "content": "Ultrasonic visualization in determination of tumor growth rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348503"}
{"pmid": "4348505", "title": "Prism adaptation and brain damage.", "content": "Prism adaptation and brain damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348505"}
{"pmid": "4348508", "title": "Indium-113 m generator using alumina or silica gel.", "content": "Indium-113 m generator using alumina or silica gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348508"}
{"pmid": "4348509", "title": "RNA-directed DNA synthesis and RNA tumor viruses.", "content": "RNA-directed DNA synthesis and RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348509"}
{"pmid": "4348512", "title": "Oxygenated cytochrome P-450 as an intermediate in hydroxylation reactions.", "content": "Oxygenated cytochrome P-450 as an intermediate in hydroxylation reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348512"}
{"pmid": "4348511", "title": "Characteristics of tumors induced in mammals, especially rodents, by viruses of the avian leukosis sarcoma group.", "content": "Characteristics of tumors induced in mammals, especially rodents, by viruses of the avian leukosis sarcoma group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348511"}
{"pmid": "4348515", "title": "Dipyrone in bronchial asthma.", "content": "Dipyrone in bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348515"}
{"pmid": "4348514", "title": "Association between malignant disease in children and maternal virus infections.", "content": "Association between malignant disease in children and maternal virus infections. The possibility of an association between virus infections during pregnancy and subsequent malignant disease in the child has been investigated using retrospective data from the Oxford Survey of Childhood Cancers. Such an association appears to exist for influenza, chickenpox, and possibly rubella. For influenza and rubella the estimated risk is small; the data do not permit an estimate to be made directly in the case of chickenpox. It is suggested that there may be a specific association between maternal chickenpox and tumours of the nervous system.It is important to emphasize that, even if the relative risk associated with these viruses is fairly large, the number of cases of childhood cancer and leukaemia actually attributable to them is probably very small.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348514"}
{"pmid": "4348516", "title": "Proteolytic activity of Entamoeba histolytica. 3. Some properties of the enzyme.", "content": "Proteolytic activity of Entamoeba histolytica. 3. Some properties of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348516"}
{"pmid": "4348510", "title": "Virus-erythrocyte interactions.", "content": "Virus-erythrocyte interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348510"}
{"pmid": "4348519", "title": "Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?", "content": "Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348519"}
{"pmid": "4348540", "title": "A proton magnetic resonance study of the conformations of 3',5'-cyclic nucleotides.", "content": "A proton magnetic resonance study of the conformations of 3',5'-cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348540"}
{"pmid": "4348541", "title": "A  13 C and  1 H nuclear magnetic resonance study of the conformations of 2',3'-cyclic nucleotides.", "content": "A  13 C and  1 H nuclear magnetic resonance study of the conformations of 2',3'-cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348541"}
{"pmid": "4348542", "title": "Enzymatic preparation of an optically active phosphotriester, asymmetric only at phosphorus.", "content": "Enzymatic preparation of an optically active phosphotriester, asymmetric only at phosphorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348542"}
{"pmid": "4348543", "title": "The effect of cycloheximide on the interaction between mitochondrial respiration and gluconeogenesis in guinea pig and rat liver.", "content": "The effect of cycloheximide on the interaction between mitochondrial respiration and gluconeogenesis in guinea pig and rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348543"}
{"pmid": "4348544", "title": "The regulation of nicotinamide adenine dinucleotide-linked substrate oxidation in isolated liver mitochondria.", "content": "The regulation of nicotinamide adenine dinucleotide-linked substrate oxidation in isolated liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348544"}
{"pmid": "4348545", "title": "A class I (Schiff base) fructose diphosphate aldolase of prokaryotic origin. Purification and properties of Micrococcus aerogenes aldolase.", "content": "A class I (Schiff base) fructose diphosphate aldolase of prokaryotic origin. Purification and properties of Micrococcus aerogenes aldolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348545"}
{"pmid": "4348546", "title": "Structural comparisons between the class I fructose diphosphate aldolases from Micrococcus aerogenes and rabbit.", "content": "Structural comparisons between the class I fructose diphosphate aldolases from Micrococcus aerogenes and rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348546"}
{"pmid": "4348547", "title": "Enzymatic epoxidation. II. Comparison between the epoxidation and hydroxylation reactions catalyzed by the  -hydroxylation system of Pseudomonas oleovorans.", "content": "Enzymatic epoxidation. II. Comparison between the epoxidation and hydroxylation reactions catalyzed by the  -hydroxylation system of Pseudomonas oleovorans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348547"}
{"pmid": "4348549", "title": "Purification and properties of the colicin E3 receptor of Escherichia coli.", "content": "Purification and properties of the colicin E3 receptor of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348549"}
{"pmid": "4348548", "title": "Formation of monoenoic fatty acids by desaturation in rat brain homogenate. Some properties of the enzyme system of 10-day-old brain.", "content": "Formation of monoenoic fatty acids by desaturation in rat brain homogenate. Some properties of the enzyme system of 10-day-old brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348548"}
{"pmid": "4348550", "title": "Regulation of adenosine 3',5'-monophosphate-dependent protein kinase. I. Preliminary characterization of the adipose tissue enzyme in crude extracts.", "content": "Regulation of adenosine 3',5'-monophosphate-dependent protein kinase. I. Preliminary characterization of the adipose tissue enzyme in crude extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348550"}
{"pmid": "4348551", "title": "Regulation of adenosine 3',5'-monophosphate-dependent protein kinase. II. Hormonal regulation of the adipose tissue enzyme.", "content": "Regulation of adenosine 3',5'-monophosphate-dependent protein kinase. II. Hormonal regulation of the adipose tissue enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348551"}
{"pmid": "4348552", "title": "Squalene synthetase. II. Purification and properties of bakers' yeast enzyme.", "content": "Squalene synthetase. II. Purification and properties of bakers' yeast enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348552"}
{"pmid": "4348553", "title": "Squalene synthetase. 3. Mechanism of the reaction.", "content": "Squalene synthetase. 3. Mechanism of the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348553"}
{"pmid": "4348554", "title": "Conditionally lethal mutations in Chinese hamster cells. I. Isolation of a temperature-sensitive line and its investigation by cell cycle studies.", "content": "Conditionally lethal mutations in Chinese hamster cells. I. Isolation of a temperature-sensitive line and its investigation by cell cycle studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348554"}
{"pmid": "4348557", "title": "Differential blood lipid pattern in diabetics and atherosclerotics.", "content": "Differential blood lipid pattern in diabetics and atherosclerotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348557"}
{"pmid": "4348558", "title": "Viruses causing common respiratory infections in man.", "content": "Viruses causing common respiratory infections in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348558"}
{"pmid": "4348556", "title": "The ability of calcium to change cyclic AMP from a stimulator to an inhibitor to thymic lymphoblast proliferation.", "content": "The ability of calcium to change cyclic AMP from a stimulator to an inhibitor to thymic lymphoblast proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348556"}
{"pmid": "4348555", "title": "Investigations of the mechanism of decreased tumorigenicity of cells grown in BrdU.", "content": "Investigations of the mechanism of decreased tumorigenicity of cells grown in BrdU.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348555"}
{"pmid": "4348559", "title": "Endocrine causes of hypertension.", "content": "Endocrine causes of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348559"}
{"pmid": "4348560", "title": "Ultrastructural cytopathology of mouse myocardium associated with EMC viral infection.", "content": "Ultrastructural cytopathology of mouse myocardium associated with EMC viral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348560"}
{"pmid": "4348561", "title": "Adenylate kinase in human tissue. II. Serum adenylate kinase and myocardial infarction.", "content": "Adenylate kinase in human tissue. II. Serum adenylate kinase and myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348561"}
{"pmid": "4348562", "title": "Patient participation in ward program planning.", "content": "Patient participation in ward program planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348562"}
{"pmid": "4348572", "title": "Identification of laboratory animals: freeze marking.", "content": "Identification of laboratory animals: freeze marking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348572"}
{"pmid": "4348564", "title": "The institutional milieu as a work environment.", "content": "The institutional milieu as a work environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348564"}
{"pmid": "4348566", "title": "Automated nursing notes in a psychiatric institution.", "content": "Automated nursing notes in a psychiatric institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348566"}
{"pmid": "4348563", "title": "Aspects of the Petrie test in psychiatric patients.", "content": "Aspects of the Petrie test in psychiatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348563"}
{"pmid": "4348573", "title": "Immunologic renal disease in laboratory animals.", "content": "Immunologic renal disease in laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348573"}
{"pmid": "4348568", "title": "Constraints and opportunities in a nursing career.", "content": "Constraints and opportunities in a nursing career.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348568"}
{"pmid": "4348565", "title": "Conjoint therapy as an adjunct to individual therapy.", "content": "Conjoint therapy as an adjunct to individual therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348565"}
{"pmid": "4348575", "title": "The plasmid of Salmonella typhimurium LT2.", "content": "The plasmid of Salmonella typhimurium LT2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348575"}
{"pmid": "4348567", "title": "Phobia: a private experience.", "content": "Phobia: a private experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348567"}
{"pmid": "4348578", "title": "A patient with multiple insulinomata.", "content": "A patient with multiple insulinomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348578"}
{"pmid": "4348576", "title": "Catecholamine and Ca 2+  activation of adenylate cyclase systems in synaptosomal fractions from rat cerebral cortex.", "content": "Catecholamine and Ca 2+  activation of adenylate cyclase systems in synaptosomal fractions from rat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348576"}
{"pmid": "4348579", "title": "Thymidine kinase activity in Burkitt lymphoblastoid somatic cell hybrids after induction of the EB virus.", "content": "Thymidine kinase activity in Burkitt lymphoblastoid somatic cell hybrids after induction of the EB virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348579"}
{"pmid": "4348569", "title": "An old fashioned method to deal with delinquent behavior: more effective than courts?", "content": "An old fashioned method to deal with delinquent behavior: more effective than courts?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348569"}
{"pmid": "4348580", "title": "Syncytial giant cell focus assay for viruses derived from feline leukemia and a simian sarcoma.", "content": "Syncytial giant cell focus assay for viruses derived from feline leukemia and a simian sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348580"}
{"pmid": "4348581", "title": "Effect of zinc on the viability and phagocytic capacity of peritoneal macrophages.", "content": "Effect of zinc on the viability and phagocytic capacity of peritoneal macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348581"}
{"pmid": "4348570", "title": "Medicare--nursing home benefits.", "content": "Medicare--nursing home benefits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348570"}
{"pmid": "4348582", "title": "Study on plasma cyclic nucleotide concentrations in fasting rats.", "content": "Study on plasma cyclic nucleotide concentrations in fasting rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348582"}
{"pmid": "4348583", "title": "The effects of an acid pH upon the induction of antiviral resistance in vitro by interferon.", "content": "The effects of an acid pH upon the induction of antiviral resistance in vitro by interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348583"}
{"pmid": "4348584", "title": "Virus resistance in rabbit kidney cell cultures contaminated by a protozoan resembling Encephalitozoon cuniculi.", "content": "Virus resistance in rabbit kidney cell cultures contaminated by a protozoan resembling Encephalitozoon cuniculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348584"}
{"pmid": "4348571", "title": "Nurses' attitude toward heroin addicts.", "content": "Nurses' attitude toward heroin addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348571"}
{"pmid": "4348585", "title": "Regulation of myocardial prostaglandin dehydrogenase activity. The role of cyclic 3',5'-AMP and calcium ions.", "content": "Regulation of myocardial prostaglandin dehydrogenase activity. The role of cyclic 3',5'-AMP and calcium ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348585"}
{"pmid": "4348586", "title": "Charge heterogeneity of human low density lipoprotein (LDL).", "content": "Charge heterogeneity of human low density lipoprotein (LDL).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348586"}
{"pmid": "4348588", "title": "Effect of angiotensin II on plasma free fatty acids in hypertensive subjects with and without overweight.", "content": "Effect of angiotensin II on plasma free fatty acids in hypertensive subjects with and without overweight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348588"}
{"pmid": "4348589", "title": "Luxation and ligamentous injuries of the elbow of the dog.", "content": "Luxation and ligamentous injuries of the elbow of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348589"}
{"pmid": "4348597", "title": "Vitamin D. Metabolism and mechanism of action.", "content": "Vitamin D. Metabolism and mechanism of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348597"}
{"pmid": "4348598", "title": "Immunity and immunopathology in virus infections.", "content": "Immunity and immunopathology in virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348598"}
{"pmid": "4348599", "title": "On the prevention of virus induced blockade of cell protein synthesis by specific inhibitors of poliovirus growth.", "content": "On the prevention of virus induced blockade of cell protein synthesis by specific inhibitors of poliovirus growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348599"}
{"pmid": "4348600", "title": "Double drug-dependence in a poliovirus strain.", "content": "Double drug-dependence in a poliovirus strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348600"}
{"pmid": "4348604", "title": "Electromagnetic measurement of iliac artery blood flow in the rat: on-line integration of flow.", "content": "Electromagnetic measurement of iliac artery blood flow in the rat: on-line integration of flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348604"}
{"pmid": "4348606", "title": "Multiple sclerosis: an immunologic reassessment.", "content": "Multiple sclerosis: an immunologic reassessment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348606"}
{"pmid": "4348607", "title": "Chemical stimulation of the brain: relationship between neural activity and water ingestion in the rat.", "content": "Chemical stimulation of the brain: relationship between neural activity and water ingestion in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348607"}
{"pmid": "4348608", "title": "Mapping and characerization of mutants of Pseudomonas aeruginosa affected in nitrate respiration in aerobic or anaerobic growth.", "content": "Mapping and characerization of mutants of Pseudomonas aeruginosa affected in nitrate respiration in aerobic or anaerobic growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348608"}
{"pmid": "4348609", "title": "Localized muscle fatigue--definiton and measurement.", "content": "Localized muscle fatigue--definiton and measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348609"}
{"pmid": "4348610", "title": "Metastatic carcinomas involving the testis: a review.", "content": "Metastatic carcinomas involving the testis: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348610"}
{"pmid": "4348611", "title": "Serological survey of rhinovirus infections in Japan.", "content": "Serological survey of rhinovirus infections in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348611"}
{"pmid": "4348602", "title": "A case of massive hypertriglyceridemia corrected by nicotinic acid or nicotinamide therapy.", "content": "A case of massive hypertriglyceridemia corrected by nicotinic acid or nicotinamide therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348602"}
{"pmid": "4348601", "title": "Effect of chlorophenoxyisobutyric acid (CPIB) on fat-mobilizing lipolysis and cyclic AMP levels in rat epididymal fat.", "content": "Effect of chlorophenoxyisobutyric acid (CPIB) on fat-mobilizing lipolysis and cyclic AMP levels in rat epididymal fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348601"}
{"pmid": "4348612", "title": "Antagonism of non-inducer ribonucleic acid against induction of antiviral cell resistance and interferon by inducer ribonucleic acid.", "content": "Antagonism of non-inducer ribonucleic acid against induction of antiviral cell resistance and interferon by inducer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348612"}
{"pmid": "4348613", "title": "Isolation and immunological characterization of human glomerular basement membrane antigens.", "content": "Isolation and immunological characterization of human glomerular basement membrane antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348613"}
{"pmid": "4348614", "title": "The effect of a reversed cycle of sleep and wakefulness on diurnal EEG patterns in rhesus monkeys.", "content": "The effect of a reversed cycle of sleep and wakefulness on diurnal EEG patterns in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348614"}
{"pmid": "4348616", "title": "Carcino-foetal human liver ferritins.", "content": "Carcino-foetal human liver ferritins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348616"}
{"pmid": "4348615", "title": "Damage to microsomal membrane by lipid peroxidation.", "content": "Damage to microsomal membrane by lipid peroxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348615"}
{"pmid": "4348617", "title": "The use of phospholipid film for shaping cell cultures.", "content": "The use of phospholipid film for shaping cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348617"}
{"pmid": "4348618", "title": "Comparison of ribosomal protein synthesis in Becker and Duchenne muscular dystrophies.", "content": "Comparison of ribosomal protein synthesis in Becker and Duchenne muscular dystrophies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348618"}
{"pmid": "4348619", "title": "Cerebral dysautoregulation in central neurogenic orthostatic hypotension (Shy-Drager syndrome).", "content": "Cerebral dysautoregulation in central neurogenic orthostatic hypotension (Shy-Drager syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348619"}
{"pmid": "4348620", "title": "On thalamic substrates of cortical synchrony.", "content": "On thalamic substrates of cortical synchrony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348620"}
{"pmid": "4348623", "title": "Electron spin resonance studies of  -irradiated dinucleotides and related compounds at 77 degrees K.", "content": "Electron spin resonance studies of  -irradiated dinucleotides and related compounds at 77 degrees K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348623"}
{"pmid": "4348622", "title": "The REM sleep-inducing action of a naturally occurring organic bromine compound in the encéphale isolé cat.", "content": "The REM sleep-inducing action of a naturally occurring organic bromine compound in the encéphale isolé cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348622"}
{"pmid": "4348624", "title": "Hepatic tumours in infancy and childhood.", "content": "Hepatic tumours in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348624"}
{"pmid": "4348625", "title": "Neurophysiological studies on muscle function in the stump of above-knee amputees.", "content": "Neurophysiological studies on muscle function in the stump of above-knee amputees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348625"}
{"pmid": "4348632", "title": "Multiple virus isolations from a pregnant patient.", "content": "Multiple virus isolations from a pregnant patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348632"}
{"pmid": "4348635", "title": "Polygraphic aspects of sleep in man.", "content": "Polygraphic aspects of sleep in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348635"}
{"pmid": "4348642", "title": "Principles of automatic analysis of sleep records with a hybrid system.", "content": "Principles of automatic analysis of sleep records with a hybrid system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348642"}
{"pmid": "4348643", "title": "Hereditary neuronal abiotrophy in the Swedish Lapland dog.", "content": "Hereditary neuronal abiotrophy in the Swedish Lapland dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348643"}
{"pmid": "4348645", "title": "Multiple effects of glucocorticoids on TSH secretion in unanesthetized rats.", "content": "Multiple effects of glucocorticoids on TSH secretion in unanesthetized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348645"}
{"pmid": "4348636", "title": "Apnoeic periods and the respiratory related arousal patterns during sleep in the Pickwickian syndrome. A polygraphic study.", "content": "Apnoeic periods and the respiratory related arousal patterns during sleep in the Pickwickian syndrome. A polygraphic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348636"}
{"pmid": "4348646", "title": "Stimulation of the adenyl cyclase-cyclic AMP system in the thyroid of the rat.", "content": "Stimulation of the adenyl cyclase-cyclic AMP system in the thyroid of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348646"}
{"pmid": "4348647", "title": "Corticosteroid feedback control of ACTH secretion: effect of stress-induced corticosterone ssecretion on subsequent stress responses in the rat.", "content": "Corticosteroid feedback control of ACTH secretion: effect of stress-induced corticosterone ssecretion on subsequent stress responses in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348647"}
{"pmid": "4348638", "title": "Insomnia, narcolepsy, and sleep apneas.", "content": "Insomnia, narcolepsy, and sleep apneas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348638"}
{"pmid": "4348648", "title": "Effects of estrogen treatment on plasma renin parameters in the rat.", "content": "Effects of estrogen treatment on plasma renin parameters in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348648"}
{"pmid": "4348649", "title": "The binding of 18-hydroxydeoxycorticosterone and 18-hydroxycorticosterone to mineralocorticoid and glucocorticoid receptors in the rat kidney.", "content": "The binding of 18-hydroxydeoxycorticosterone and 18-hydroxycorticosterone to mineralocorticoid and glucocorticoid receptors in the rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348649"}
{"pmid": "4348637", "title": "Hypersomnia with periodic breathing: periodic apneas and alveolar hypoventilation during sleep.", "content": "Hypersomnia with periodic breathing: periodic apneas and alveolar hypoventilation during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348637"}
{"pmid": "4348650", "title": "Pinealectomy and brain myelination.", "content": "Pinealectomy and brain myelination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348650"}
{"pmid": "4348651", "title": "Evidence for a new class of corticosterone receptors in the rat kidney.", "content": "Evidence for a new class of corticosterone receptors in the rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348651"}
{"pmid": "4348640", "title": "Tracheostomy in hypersomnia with periodic breathing.", "content": "Tracheostomy in hypersomnia with periodic breathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348640"}
{"pmid": "4348639", "title": "Continuous recording of the pulmonary and systemic arterial pressure during sleep in syndromes of hypersomnia with periodic breathing.", "content": "Continuous recording of the pulmonary and systemic arterial pressure during sleep in syndromes of hypersomnia with periodic breathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348639"}
{"pmid": "4348652", "title": "Role of pancreatic monoamines in the impaired insulin secretion of the fasting state.", "content": "Role of pancreatic monoamines in the impaired insulin secretion of the fasting state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348652"}
{"pmid": "4348654", "title": "Effect of adrenocorticotropic hormone on extracellular adenosine 3',5'-monophosphate in the hypophysectomized rat.", "content": "Effect of adrenocorticotropic hormone on extracellular adenosine 3',5'-monophosphate in the hypophysectomized rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348654"}
{"pmid": "4348655", "title": "The metabolism of perchlorate in the rat.", "content": "The metabolism of perchlorate in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348655"}
{"pmid": "4348653", "title": "Nuclear receptor-estrogen complex: relationship between concentration and early uterotrophic responses.", "content": "Nuclear receptor-estrogen complex: relationship between concentration and early uterotrophic responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348653"}
{"pmid": "4348656", "title": "Effect of hypophysectomy on serum dopamine-beta-hydroxylase activity in rat.", "content": "Effect of hypophysectomy on serum dopamine-beta-hydroxylase activity in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348656"}
{"pmid": "4348641", "title": "Hydrochlorothiazide therapy in nephrolithiasis. Effect on the urinary activity product and formation product of brushite.", "content": "Hydrochlorothiazide therapy in nephrolithiasis. Effect on the urinary activity product and formation product of brushite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348641"}
{"pmid": "4348657", "title": "Peripheral levels of estrogen in the PMS-primed cycling hamster.", "content": "Peripheral levels of estrogen in the PMS-primed cycling hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348657"}
{"pmid": "4348658", "title": "Ouabain stimulation of  45 CA ++  accumulation in the rat pituitary.", "content": "Ouabain stimulation of  45 CA ++  accumulation in the rat pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348658"}
{"pmid": "4348659", "title": "Hormonal factors influencing ovarian uptake of human chorionic gonadotropin.", "content": "Hormonal factors influencing ovarian uptake of human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348659"}
{"pmid": "4348660", "title": "Anomalous prolactin release in vitro in response to cold and its specific blockade by a purified hypothalamic-inhibiting factor.", "content": "Anomalous prolactin release in vitro in response to cold and its specific blockade by a purified hypothalamic-inhibiting factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348660"}
{"pmid": "4348661", "title": "Characterization of human corneal collagenase.", "content": "Characterization of human corneal collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348661"}
{"pmid": "4348662", "title": "Discharge plans--the weakest link.", "content": "Discharge plans--the weakest link.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348662"}
{"pmid": "4348663", "title": "Study of cellular inclusion in the human foetal intestinal neuron.", "content": "Study of cellular inclusion in the human foetal intestinal neuron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348663"}
{"pmid": "4348664", "title": "Prevalence of amoebiasis and other intestinal parasitic infections in a selected community.", "content": "Prevalence of amoebiasis and other intestinal parasitic infections in a selected community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348664"}
{"pmid": "4348665", "title": "Evaluation of laboratory methods in the detection of E. histolytica and other intestinal parasites.", "content": "Evaluation of laboratory methods in the detection of E. histolytica and other intestinal parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348665"}
{"pmid": "4348666", "title": "Does entrapment neuropathy contribute to nerve damage in leprosy?", "content": "Does entrapment neuropathy contribute to nerve damage in leprosy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348666"}
{"pmid": "4348667", "title": "The use of cord serum and indirect viral immunofluorescence as a method of evaluating the immunological specificity of fluorescein-labelled anti-human IgA conjugate.", "content": "The use of cord serum and indirect viral immunofluorescence as a method of evaluating the immunological specificity of fluorescein-labelled anti-human IgA conjugate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348667"}
{"pmid": "4348668", "title": "Coagulation and renal disease.", "content": "Coagulation and renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348668"}
{"pmid": "4348671", "title": "A comparison of the antilipolytic effects of nicotinic acid, methylisoxazole carboxylic acid, methylpyrazole carboxylic acid and insulin in isolated fat cells.", "content": "A comparison of the antilipolytic effects of nicotinic acid, methylisoxazole carboxylic acid, methylpyrazole carboxylic acid and insulin in isolated fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348671"}
{"pmid": "4348672", "title": "A novel assay for erythrocyte carbonic anhydrase and certain sulfonamide drugs employing spin-labels.", "content": "A novel assay for erythrocyte carbonic anhydrase and certain sulfonamide drugs employing spin-labels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348672"}
{"pmid": "4348673", "title": "The effect of corticotrophin on the compartmental arrangement of steroids, and the control of steroid hormone secretion by the rat adrenal cortex in vitro.", "content": "The effect of corticotrophin on the compartmental arrangement of steroids, and the control of steroid hormone secretion by the rat adrenal cortex in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348673"}
{"pmid": "4348674", "title": "Preparation of oestriol-6-(O-carboxymethyl) oxime and oestrone-6-(carboxymethyl) oxime-bovine serum albumin conjugates.", "content": "Preparation of oestriol-6-(O-carboxymethyl) oxime and oestrone-6-(carboxymethyl) oxime-bovine serum albumin conjugates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348674"}
{"pmid": "4348676", "title": "On the oscillatory potentials of the human electroretinogram in light and dark adaptation.", "content": "On the oscillatory potentials of the human electroretinogram in light and dark adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348676"}
{"pmid": "4348678", "title": "A reappraisal of histopathology in lung cancer and correlation of cell types with antecedent cigarette smoking.", "content": "A reappraisal of histopathology in lung cancer and correlation of cell types with antecedent cigarette smoking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348678"}
{"pmid": "4348683", "title": "Subcellular location of the kininogenase in the coagulating gland of the guinea-pig.", "content": "Subcellular location of the kininogenase in the coagulating gland of the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348683"}
{"pmid": "4348684", "title": "Studies on cytochrome c. V. Synthesis of the protected decapeptide (sequence 57-66) of Baker's yeast iso-1-cytochrome c.", "content": "Studies on cytochrome c. V. Synthesis of the protected decapeptide (sequence 57-66) of Baker's yeast iso-1-cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348684"}
{"pmid": "4348686", "title": "Studies on cytochrome c. VII. Synthesis of the protected undecapeptide (sequence 82-92) of Baker's yeast iso-1-cytochrome c.", "content": "Studies on cytochrome c. VII. Synthesis of the protected undecapeptide (sequence 82-92) of Baker's yeast iso-1-cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348686"}
{"pmid": "4348685", "title": "Studies on cytochrome c. VI. Synthesis of the protected pentadecapeptide (sequence 64-81) of Baker's yeast iso-1-cytochrome c.", "content": "Studies on cytochrome c. VI. Synthesis of the protected pentadecapeptide (sequence 64-81) of Baker's yeast iso-1-cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348685"}
{"pmid": "4348688", "title": "Actinomycin D for Wilm's tumor.", "content": "Actinomycin D for Wilm's tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348688"}
{"pmid": "4348687", "title": "Studies on cytochrome c. 8. Synthesis of the protected hexadecapeptide (sequence 93-108) of Baker's yeast iso-1-cytochrome c.", "content": "Studies on cytochrome c. 8. Synthesis of the protected hexadecapeptide (sequence 93-108) of Baker's yeast iso-1-cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348687"}
{"pmid": "4348689", "title": "Glomus tumours.", "content": "Glomus tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348689"}
{"pmid": "4348690", "title": "Vincristine neuropathy. Clinical and electrophysiological observations.", "content": "Vincristine neuropathy. Clinical and electrophysiological observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348690"}
{"pmid": "4348691", "title": "Phagocytosis by alveolar macrophages: pharmacologic features.", "content": "Phagocytosis by alveolar macrophages: pharmacologic features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348691"}
{"pmid": "4348692", "title": "Retarded clearance of macroaggregated albumin from the lung of asthmatic patients.", "content": "Retarded clearance of macroaggregated albumin from the lung of asthmatic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348692"}
{"pmid": "4348693", "title": "Role of viral infection and host factors in acute episodes of asthma and chronic bronchitis.", "content": "Role of viral infection and host factors in acute episodes of asthma and chronic bronchitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348693"}
{"pmid": "4348696", "title": "Quantitative analysis of phenolic compounds after thin-layer chromatographic separation.", "content": "Quantitative analysis of phenolic compounds after thin-layer chromatographic separation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348696"}
{"pmid": "4348697", "title": "Thin-layer chromatography for quantitative polychlorinated biphenyl analysis.", "content": "Thin-layer chromatography for quantitative polychlorinated biphenyl analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348697"}
{"pmid": "4348698", "title": "The juvenile angiofibroma of the nasopharynx.", "content": "The juvenile angiofibroma of the nasopharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348698"}
{"pmid": "4348699", "title": "Effect of hypophysectomy, isletectomy and ACTH on glycemia and hematocrit in the bullhead, Ictalurus melas.", "content": "Effect of hypophysectomy, isletectomy and ACTH on glycemia and hematocrit in the bullhead, Ictalurus melas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348699"}
{"pmid": "4348700", "title": "Studies on carcinogenic bifunctional aminoazo dyes. IV. Progressive microscopic alternation in the livers of rats fed the carcinogenic bifunctional aminoazo dyes: (N', N'-dimethyl-4'-amino)-N-acetyl-N-monomethyl-4-aminoazobenzene.", "content": "Studies on carcinogenic bifunctional aminoazo dyes. IV. Progressive microscopic alternation in the livers of rats fed the carcinogenic bifunctional aminoazo dyes: (N', N'-dimethyl-4'-amino)-N-acetyl-N-monomethyl-4-aminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348700"}
{"pmid": "4348701", "title": "Cyclic AMP and its binding protein in the stimulated thyroid of the rat.", "content": "Cyclic AMP and its binding protein in the stimulated thyroid of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348701"}
{"pmid": "4348703", "title": "Thermoregulatory effects of prostaglandins E 1 , E 2 , F 1   and F 2   in the sheep.", "content": "Thermoregulatory effects of prostaglandins E 1 , E 2 , F 1   and F 2   in the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348703"}
{"pmid": "4348702", "title": "3',5'-cyclic AMP phosphodiesterases in cytosol of uterine smooth muscle; effects of angiotensin.", "content": "3',5'-cyclic AMP phosphodiesterases in cytosol of uterine smooth muscle; effects of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348702"}
{"pmid": "4348706", "title": "Tumor immunology.", "content": "Tumor immunology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348706"}
{"pmid": "4348707", "title": "Histocompatibility antigens and species-specific antigens.", "content": "Histocompatibility antigens and species-specific antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348707"}
{"pmid": "4348695", "title": "Development of a diploid cell line from fetal rhesus monkey lung for virus vaccine production.", "content": "Development of a diploid cell line from fetal rhesus monkey lung for virus vaccine production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348695"}
{"pmid": "4348708", "title": "Induction of specific unresponsiveness with the aid of Bordetella pertussis.", "content": "Induction of specific unresponsiveness with the aid of Bordetella pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348708"}
{"pmid": "4348709", "title": "Isolation of islets of Langerhans for transplantation.", "content": "Isolation of islets of Langerhans for transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348709"}
{"pmid": "4348710", "title": "Role of virus infections in immunosuppressed renal transplant patients.", "content": "Role of virus infections in immunosuppressed renal transplant patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348710"}
{"pmid": "4348711", "title": "Cytotoxicity of Rous sarcoma cells by lymphoid cells in Japanese quails.", "content": "Cytotoxicity of Rous sarcoma cells by lymphoid cells in Japanese quails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348711"}
{"pmid": "4348712", "title": "Depressed allograft immunity in leukemia virus infected mice.", "content": "Depressed allograft immunity in leukemia virus infected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348712"}
{"pmid": "4348716", "title": "The Epstein-Barr Virus (EBV) and Marek's Disease.", "content": "The Epstein-Barr Virus (EBV) and Marek's Disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348716"}
{"pmid": "4348717", "title": "Optimal growth conditions for (Ibadan) strains of Entamoeba histolytica.", "content": "Optimal growth conditions for (Ibadan) strains of Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348717"}
{"pmid": "4348705", "title": "Role of hormones of adrenal cortex and ovaries of pregnant mother in stress reaction of rat fetus.", "content": "Role of hormones of adrenal cortex and ovaries of pregnant mother in stress reaction of rat fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348705"}
{"pmid": "4348718", "title": "The extra-articular features of rheumatoid arthritis. A systematic analysis of 127 cases.", "content": "The extra-articular features of rheumatoid arthritis. A systematic analysis of 127 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348718"}
{"pmid": "4348719", "title": "A mucopolysaccharide storage disease with involvement of the renal glomerular epithelium.", "content": "A mucopolysaccharide storage disease with involvement of the renal glomerular epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348719"}
{"pmid": "4348720", "title": "Corticosteroidogenesis in isolated adrenal cell preparations of vitamin E-deficient rats.", "content": "Corticosteroidogenesis in isolated adrenal cell preparations of vitamin E-deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348720"}
{"pmid": "4348721", "title": "The dynamics of vitamin E transport in the human erythrocyte.", "content": "The dynamics of vitamin E transport in the human erythrocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348721"}
{"pmid": "4348714", "title": "Hepatocarcinoma with biliary obstruction. Report of a case and review of the literature.", "content": "Hepatocarcinoma with biliary obstruction. Report of a case and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348714"}
{"pmid": "4348722", "title": "The cellular mechanisms of vitamin E action: direct and indirect effects of  -tocopherol on mitochondrial respiration.", "content": "The cellular mechanisms of vitamin E action: direct and indirect effects of  -tocopherol on mitochondrial respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348722"}
{"pmid": "4348723", "title": "Pathogenesis of demyelination induced by a mouse hepatitis.", "content": "Pathogenesis of demyelination induced by a mouse hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348723"}
{"pmid": "4348724", "title": "Nuclear DNA in salivary gland tumors. I. Warthin tumors, benign mixed tumors, and mucoepidermoid carcinomas.", "content": "Nuclear DNA in salivary gland tumors. I. Warthin tumors, benign mixed tumors, and mucoepidermoid carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348724"}
{"pmid": "4348725", "title": "Fine structure of Toxoplasma in the human brain.", "content": "Fine structure of Toxoplasma in the human brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348725"}
{"pmid": "4348726", "title": "Peliosis hepatis. Possible etiologic role of anabolic steroids.", "content": "Peliosis hepatis. Possible etiologic role of anabolic steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348726"}
{"pmid": "4348728", "title": "Urea-induced inactivation and dissociation of NAD-specific glutamate dehydrogenase of Neurospora and its reversal by substrates.", "content": "Urea-induced inactivation and dissociation of NAD-specific glutamate dehydrogenase of Neurospora and its reversal by substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348728"}
{"pmid": "4348729", "title": "The electron paramagnetic resonance spectrum of ferricytochrome c and lysine-modified derivatives at alkaline pH.", "content": "The electron paramagnetic resonance spectrum of ferricytochrome c and lysine-modified derivatives at alkaline pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348729"}
{"pmid": "4348730", "title": "The pH-induced transition of iodinated ferricytochrome c: electron paramagnetic resonance and absorption spectra.", "content": "The pH-induced transition of iodinated ferricytochrome c: electron paramagnetic resonance and absorption spectra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348730"}
{"pmid": "4348731", "title": "A comparison of the secretion of two components of very low density lipoproteins by perfused rat liver.", "content": "A comparison of the secretion of two components of very low density lipoproteins by perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348731"}
{"pmid": "4348732", "title": "The technique and applications of lymphography.", "content": "The technique and applications of lymphography. The technique of radiographic examination by lymphography of normal lymphatic structures regional to the hind limbs is described in the rabbit, dog and rhesus monkey. Radiographic appearances of normal lymph nodes and possible applications to veterinary science are indicated.Normal lymph node microstructure is illustrated using in vivo intralymphatic injection of a brightly colored radiopaque silicone rubber. Angiogenesis in active germinal follicles during the period of an immune response is displayed. Further applications of the casting technique are suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348732"}
{"pmid": "4348733", "title": "Collagenolytic activity of gingivae from alloxan-diabetic rats.", "content": "Collagenolytic activity of gingivae from alloxan-diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348733"}
{"pmid": "4348734", "title": "Effect of morphine on the transport of dopamine into mouse brain slices.", "content": "Effect of morphine on the transport of dopamine into mouse brain slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348734"}
{"pmid": "4348735", "title": "Effects of angiotensin-II on myocardial mechanics and contractile state of heart muscle.", "content": "Effects of angiotensin-II on myocardial mechanics and contractile state of heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348735"}
{"pmid": "4348727", "title": "Nicotinic acid and nicotinamide adenine dinucleotide (NAD) therapy in schizophrenia: a review.", "content": "Nicotinic acid and nicotinamide adenine dinucleotide (NAD) therapy in schizophrenia: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348727"}
{"pmid": "4348736", "title": "The biphasic response of the isolated guinea-pig ileum by bradykinin.", "content": "The biphasic response of the isolated guinea-pig ileum by bradykinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348736"}
{"pmid": "4348737", "title": "Effect of angiotensin on the response to norepinephrine and peri-arterial stimulation of the isolated perfused cat terminal ileum.", "content": "Effect of angiotensin on the response to norepinephrine and peri-arterial stimulation of the isolated perfused cat terminal ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348737"}
{"pmid": "4348738", "title": "N-methyl bicuculline and primary afferent depolarization.", "content": "N-methyl bicuculline and primary afferent depolarization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348738"}
{"pmid": "4348740", "title": "The cytomegaloviruses and the eye.", "content": "The cytomegaloviruses and the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348740"}
{"pmid": "4348742", "title": "Characterization of bovine serum lipoproteins.", "content": "Characterization of bovine serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348742"}
{"pmid": "4348741", "title": "Isolation and partial characterization of temperature-sensitive mutants of the SAT-1 strain of foot-and-mouth disease virus.", "content": "Isolation and partial characterization of temperature-sensitive mutants of the SAT-1 strain of foot-and-mouth disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348741"}
{"pmid": "4348743", "title": "Preparation and metabolism of isolated cells from bovine adipose tissue.", "content": "Preparation and metabolism of isolated cells from bovine adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348743"}
{"pmid": "4348744", "title": "Double antibody radioimmunoassay of renin activity and angiotensin II in human peripheral plasma.", "content": "Double antibody radioimmunoassay of renin activity and angiotensin II in human peripheral plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348744"}
{"pmid": "4348745", "title": "Electron microscopic study of ATPase activity in human brain tumors.", "content": "Electron microscopic study of ATPase activity in human brain tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348745"}
{"pmid": "4348747", "title": "Myoneural and intermuscular junctions in a molluscan smooth muscle.", "content": "Myoneural and intermuscular junctions in a molluscan smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348747"}
{"pmid": "4348746", "title": "Stereotaxic diagnosis and treatment of intracranial tumors including an initial experience with cryosurgery for pinealomas.", "content": "Stereotaxic diagnosis and treatment of intracranial tumors including an initial experience with cryosurgery for pinealomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348746"}
{"pmid": "4348748", "title": "The effect of Triton X-100 on the ultrastructure of ejaculated bovine sperm.", "content": "The effect of Triton X-100 on the ultrastructure of ejaculated bovine sperm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348748"}
{"pmid": "4348749", "title": "Lithium-induced ADH resistance in toad urinary bladders.", "content": "Lithium-induced ADH resistance in toad urinary bladders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348749"}
{"pmid": "4348750", "title": "The choice of therapy in the treatment of malignancy.", "content": "The choice of therapy in the treatment of malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348750"}
{"pmid": "4348751", "title": "Amyloid in endocrine tumors.", "content": "Amyloid in endocrine tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348751"}
{"pmid": "4348752", "title": "The use of drugs in combination for the treatment of cancer: rationale and results.", "content": "The use of drugs in combination for the treatment of cancer: rationale and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348752"}
{"pmid": "4348753", "title": "Marginal vitamin B 12  intake during gestation in the rat has long term effects on the offspring.", "content": "Marginal vitamin B 12  intake during gestation in the rat has long term effects on the offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348753"}
{"pmid": "4348758", "title": "A simple method for estimating H 1  in ESR experiments--the microwave power saturation of  -irradiation induced glycylglycine radicals.", "content": "A simple method for estimating H 1  in ESR experiments--the microwave power saturation of  -irradiation induced glycylglycine radicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348758"}
{"pmid": "4348764", "title": "Effect of dieldrin on hepatic carbohydrate metabolism and protein biosynthesis in vivo.", "content": "Effect of dieldrin on hepatic carbohydrate metabolism and protein biosynthesis in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348764"}
{"pmid": "4348765", "title": "Effect of colloidal silicic acid on lecithin bilayers.", "content": "Effect of colloidal silicic acid on lecithin bilayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348765"}
{"pmid": "4348766", "title": "Bilayer lipid membrane as a model for vasopressin, prostaglandin and Ca 2+  effects on water permeability.", "content": "Bilayer lipid membrane as a model for vasopressin, prostaglandin and Ca 2+  effects on water permeability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348766"}
{"pmid": "4348767", "title": "Plasma membranes from fibroblastic cells in culture. Isolation, morphological and enzymatic identification.", "content": "Plasma membranes from fibroblastic cells in culture. Isolation, morphological and enzymatic identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348767"}
{"pmid": "4348768", "title": "Enzyme activities in membranes from three phenotypes of the murine plasmocytoma MOPC 173, cultivated in vitro.", "content": "Enzyme activities in membranes from three phenotypes of the murine plasmocytoma MOPC 173, cultivated in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348768"}
{"pmid": "4348769", "title": "Metabolically controlled hemolysis of chicken erythrocytes.", "content": "Metabolically controlled hemolysis of chicken erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348769"}
{"pmid": "4348770", "title": "Isolation of pig platelet membranes and granules. Distribution and validity of marker enzymes.", "content": "Isolation of pig platelet membranes and granules. Distribution and validity of marker enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348770"}
{"pmid": "4348771", "title": "Studies of neoplastic myelomonocytic cells in BALB-c mice producing infectious C-type viruses.", "content": "Studies of neoplastic myelomonocytic cells in BALB-c mice producing infectious C-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348771"}
{"pmid": "4348772", "title": "Ultrastructural studies of histiocyte-tumor cell interactions during tumor regression after intralesional injection of Mycobacterium bovis.", "content": "Ultrastructural studies of histiocyte-tumor cell interactions during tumor regression after intralesional injection of Mycobacterium bovis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348772"}
{"pmid": "4348773", "title": "Characterization of glycogen synthetases and phosphorylases in transplantable rat hepatomas.", "content": "Characterization of glycogen synthetases and phosphorylases in transplantable rat hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348773"}
{"pmid": "4348774", "title": "Enhancement of virus-induced leukemias and sarcomas in F 1  hybrid mice inoculated with parental spleen cells.", "content": "Enhancement of virus-induced leukemias and sarcomas in F 1  hybrid mice inoculated with parental spleen cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348774"}
{"pmid": "4348775", "title": "Independence of pituitary tumor-mediated suppression of growth hormone secretion and cyclic 3',5'-adenosine monophosphate production.", "content": "Independence of pituitary tumor-mediated suppression of growth hormone secretion and cyclic 3',5'-adenosine monophosphate production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348775"}
{"pmid": "4348777", "title": "Sulfated mucopolysaccharide production by synovial sarcoma cells in vivo and in tissue culture.", "content": "Sulfated mucopolysaccharide production by synovial sarcoma cells in vivo and in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348777"}
{"pmid": "4348776", "title": "Suppression of pituitary tumor growth and function by ergot alkaloids.", "content": "Suppression of pituitary tumor growth and function by ergot alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348776"}
{"pmid": "4348778", "title": "Chromatographic studies of tyrosyl and phenylalanyl transfer RNA's of liver and tumor cells.", "content": "Chromatographic studies of tyrosyl and phenylalanyl transfer RNA's of liver and tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348778"}
{"pmid": "4348783", "title": "Effects of age on patterns of enzyme adaptation in male and female rats.", "content": "Effects of age on patterns of enzyme adaptation in male and female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348783"}
{"pmid": "4348784", "title": "Octahedral crystals in Phycomyces. II.", "content": "Octahedral crystals in Phycomyces. II. \"Phycomyces blakesleeanus\" sporangiophores contain octahedral crystals throughout their cytoplasm and vacuole. More octahedral crystals were found in the wild-type strain G5 (+) than in the beta-carotene-deficient mutant C5 (-), and much more than in the mutant C141 (-), which is sensitive to only high light intensity. In the wild type, the number of crystals per sporangiophore increased until the sporangiophore reached stage IV, and then decreased. Stage I contained the most crystals per unit volume. Cultures grown in darkness had the maximum number of crystals. Under high light intensity, there was an overall reduction of crystals. The crystals are regular octahedrons. The crystals were isolated from the sporangiophores by a method of sucrose density-gradient centrifugation. They contain nearly 95% protein, are stable in organic solvents, but can be solubilized in buffer solution above pH 9.5 and below 2.5. The crystals weakly fluoresce with an emission peak at 540 nm, which is affected by irradiation with white light. Absorption spectra of freshly prepared crystals show absorption maxima around 265-285 nm, 350-380 nm, and 450-470 nm. These absorption peaks for the crystals are close to those of the phototropic and light-growth action spectra. These data suggest that the crystals may contain a flavoprotein which may be the photoreceptor pigment of \"Phycomyces\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348784"}
{"pmid": "4348785", "title": "Appearance and distribution of ferritin in mouse peritoneal macrophages in vitro after uptake of heterologous erythrocytes.", "content": "Appearance and distribution of ferritin in mouse peritoneal macrophages in vitro after uptake of heterologous erythrocytes. Mouse peritoneal macrophages have been studied in vitro after ingestion of treated rat, rabbit, or sheep erythrocytes. Under light microscopy, phagocytic vacuoles persist up to 24 h. Macrophages lose benzidine reactivity about 5 h after red cell ingestion, and they become prussian blue positive at 2 days. Ultrastructural studies show little or no ferritin in control macrophages not fed erythrocytes. In contrast, after red cell ingestion, ferritin is widely distributed in the cytoplasmic matrix and in some cytoplasmic granules by 48 h. The Golgi complex, pinocytic vacuoles, endoplasmic reticulum, nuclei, and mitochondria do not contain ferritin. Between 2 and 4 days, ferritin in cytoplasmic granules increases, concomitant with decrease in the ferritin in the cytoplasmic matrix. Evidence is presented suggesting that ferritin in the cytoplasmic matrix is translocated into cytoplasmic granules by autophagy. Polyacrylamide gel studies on macrophages after uptake of red blood cells labeled with radioiron confirm that macrophages produce radiolabeled ferritin by 4 days.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348785"}
{"pmid": "4348787", "title": "Enhancement of Sendai virus-mediated cell fusion by cupric ions.", "content": "Enhancement of Sendai virus-mediated cell fusion by cupric ions. The effect of divalent cations on cell fusion by concentrated Sendai virus, inactivated by beta-propiolactone, was investigated using Vero and mouse L-929 cells in monolayers. With both cell lines, which are normally resistant to exogenous viral fusion, Cu(2+) in sublethal concentrations was found to promote polykaryon formation to a marked degree. The simultaneous presence of Cu(2+) and virus was required for this effect, which was thought to be related to the cytotoxic action of Cu(2+) on the cell membrane. Accordingly, under standard conditions and in the absence of virus, leakage of isotopically labeled intracellular protein was shown to bear a quantitative relationship to Cu(2+) concentration. Concomitant changes in the membrane were seen electron microscopically to consist of loss of microvilli and the appearance of numerous vesicles on, or adjacent to, the membrane. The relationship of enhanced fusibility to these toxic changes was not further elucidated. The fusion-promoting effect of Cu(2+) far exceeded that of Ca(2+); and other cations tested had no effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348787"}
{"pmid": "4348786", "title": "Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junction.", "content": "Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junction. When the nerves of isolated frog sartorius muscles were stimulated at 10 Hz, synaptic vesicles in the motor nerve terminals became transiently depleted. This depletion apparently resulted from a redistribution rather than disappearance of synaptic vesicle membrane, since the total amount of membrane comprising these nerve terminals remained constant during stimulation. At 1 min of stimulation, the 30% depletion in synaptic vesicle membrane was nearly balanced by an increase in plasma membrane, suggesting that vesicle membrane rapidly moved to the surface as it might if vesicles released their content of transmitter by exocytosis. After 15 min of stimulation, the 60% depletion of synaptic vesicle membrane was largely balanced by the appearance of numerous irregular membrane-walled cisternae inside the terminals, suggesting that vesicle membrane was retrieved from the surface as cisternae. When muscles were rested after 15 min of stimulation, cisternae disappeared and synaptic vesicles reappeared, suggesting that cisternae divided to form new synaptic vesicles so that the original vesicle membrane was now recycled into new synaptic vesicles. When muscles were soaked in horseradish peroxidase (HRP), this tracerfirst entered the cisternae which formed during stimulation and then entered a large proportion of the synaptic vesicles which reappeared during rest, strengthening the idea that synaptic vesicle membrane added to the surface was retrieved as cisternae which subsequently divided to form new vesicles. When muscles containing HRP in synaptic vesicles were washed to remove extracellular HRP and restimulated, HRP disappeared from vesicles without appearing in the new cisternae formed during the second stimulation, confirming that a one-way recycling of synaptic membrane, from the surface through cisternae to new vesicles, was occurring. Coated vesicles apparently represented the actual mechanism for retrieval of synaptic vesicle membrane from the plasma membrane, because during nerve stimulation they proliferated at regions of the nerve terminals covered by Schwann processes, took up peroxidase, and appeared in various stages of coalescence with cisternae. In contrast, synaptic vesicles did not appear to return directly from the surface to form cisternae, and cisternae themselves never appeared directly connected to the surface. Thus, during stimulation the intracellular compartments of this synapse change shape and take up extracellular protein in a manner which indicates that synaptic vesicle membrane added to the surface during exocytosis is retrieved by coated vesicles and recycled into new synaptic vesicles by way of intermediate cisternae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348786"}
{"pmid": "4348788", "title": "Growth inhibition of murine tumor cells, in vitro, by puromycin, ( 6 N)O 2 '-dibutyryl 3',5'-adenosine monophosphate, or adenosine: evidence of commitment for cell division.", "content": "Growth inhibition of murine tumor cells, in vitro, by puromycin, ( 6 N)O 2 '-dibutyryl 3',5'-adenosine monophosphate, or adenosine: evidence of commitment for cell division. The cytostatic effects of puromycm, [(6)N]O(2')-dibutyryl 3',5'-adenosine monophosphate, and adenosine on asynchronous and synchronous cultures of the murine mastocytoma, P815Y, have been studied. Cell growth was arrested after a minimum of one further division. A model is proposed for the inhibition of cell division in which the periods of inhibition and growth arrest are separated in time by one cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348788"}
{"pmid": "4348789", "title": "Subcellular morphometric and biochemical analysis of developing rat hepatocytes.", "content": "Subcellular morphometric and biochemical analysis of developing rat hepatocytes. Livers of rats between the 16th gestational and 100th postnatal day of age were subjected to quantitative biochemical and electron microscope, morphometric analyses. The amount of total mitochondrial protein per gram of liver remained at 34% of the adult level throughout the last 4 days of gestation but this was the period of rapid rise in the levels of cytochrome c oxidase, aspartate aminotransferase, and glutamate dehydrogenase in mitochondria; the nuclear fraction also acquired some glutamate dehydrogenase but lost most of it during postnatal development. During early postnatal life the amount of mitochondrial protein rose in parallel with the levels of cytochrome c oxidase and glutamate dehydrogenase but the upsurges of glutaminase and, later, of ornithine aminotransferase were accompanied by relatively little change in total mitochondrial protein. The surface area of rough endoplasmic reticulum per unit volume of hepatocyte cytoplasm (S(v) (RER)) did not change significantly throughout the period of development studied. From the 16th day of gestation to term the surface area of smooth ER (S(v) (SER)), the volume occupied by mitochondria (V(v) (MT)) and their number (N(v) (MT)) remained at 30, 66, and 45% of their adult values, respectively. V(v) (MT) and N(v) (MT) attained their maximal levels by the 2nd postnatal day and S(v) (SER) between days 2 and 12. Mitochondria of adult liver are thus smaller and contain more protein per unit volume than do those of fetal liver. After the 12th postnatal day, hepatocytes treble their size; they acquire more cytoplasm with additional enzymes but without further change in organelle concentration. The data reveal several distinct phases in the differentiation of hepatocytes. Each phase can be characterized by the extent to which the quantity and composition of various subcellular compartments evolve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348789"}
{"pmid": "4348791", "title": "Turnover of transmitter and synaptic vesicles at the frog neuromuscular junction.", "content": "Turnover of transmitter and synaptic vesicles at the frog neuromuscular junction. Curarized cutaneous pectoris nerve-muscle preparations from frogs were stimulated at 10/s or at 2/s for periods ranging from 20 min to 4 h. End plate potential were recorded intracellularly and used to estimate the quantity of transmitter secreted during the period of stimulation. At the ends of the periods of stimulation the preparations were either fixed for electron microscopy or treated with black widow spider venom to determine the quantities of transmitter remainind in the terminal. Horseradish peroxidase or dextran was added to the bathing solution and used as a tracer to detect the formation of vesicles from the axolemma. During 4 h of stimulation at 2/s many new vesicles were formed from the axolemma and the quantity of transmitter secreted was several times greater than the quantity in the initial store. After this period of stimulation, the terminals were severely depleted of transmitter, but not of vesicles, and their general morphological organization was normal. During 20 min of stimulation at 10/s the nerve terminals swelled and were severely depleted both of vesicles and of transmitter. During a subsequent hour of rest the changes in morphology were largely reversed, many new vesicles were formed from the axolemma and the stores of transmitter were partially replenished. These results suggest (a) that synaptic vesicles fuse with, and re-form from, the membrane of the nerve terminal during and after stimulation and (b), that the re-formed vesicles can store and release transmitter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348791"}
{"pmid": "4348792", "title": "Cyclic adenosine monophosphate in phagocytizing granulocytes and alveolar macrophages.", "content": "Cyclic adenosine monophosphate in phagocytizing granulocytes and alveolar macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348792"}
{"pmid": "4348790", "title": "The effect of poly-L-lysine on the uptake of reovirus double-stranded RNA in macrophages in vitro.", "content": "The effect of poly-L-lysine on the uptake of reovirus double-stranded RNA in macrophages in vitro. The effect of polycations on cultured mouse peitoneal macrophages has been examined. Polycations, at concentrations greater than 5 microg/ml, are toxic for macrophages) as measured by failure of the cells to exclude vital dyes. At toxic concentrations polycations bind in large amounts to nuclei and endoplasmic reticulum, while at nontoxic levels polycations bind selectively to the cell surface. Nontoxic concentrations of polycations stimulate binding of reovirus double-stranded (ds) RNA to the macrophages by forming polycation-dsRNA complexes either in the medium or at the cell surface. These complexes enter the cell in endocytic vacuoles and are concentrated in secondary lysosomes. Despite exposure to the acid hydrolases within this cell compartment, the dsRNA and the polycation (poly-L-lysine) are conserved in a macromolecular form within the vacuolar system. The mechanism(s) by which the uptake of infectious nucleic acids and the induction of interferon by dsRNA are stimulated by polycations are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348790"}
{"pmid": "4348794", "title": "Transmission of maternal antibodies to Sendai virus in mice and its significance in enzootic infection.", "content": "Transmission of maternal antibodies to Sendai virus in mice and its significance in enzootic infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348794"}
{"pmid": "4348796", "title": "Genetic studies with herpes simplex virus type 1. The isolation of temperature-sensitive mutants, their arrangement into complementation groups and recombination analysis leading to a linkage map.", "content": "Genetic studies with herpes simplex virus type 1. The isolation of temperature-sensitive mutants, their arrangement into complementation groups and recombination analysis leading to a linkage map.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348796"}
{"pmid": "4348795", "title": "The possible nature of the chance-event in initiation of virus infection at the cellular level.", "content": "The possible nature of the chance-event in initiation of virus infection at the cellular level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348795"}
{"pmid": "4348797", "title": "Genetic interactions between temperature-sensitive mutants of types 1 and 2 herpes simplex viruses.", "content": "Genetic interactions between temperature-sensitive mutants of types 1 and 2 herpes simplex viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348797"}
{"pmid": "4348798", "title": "A practical and quantitative microtest for determination of neutralizing antibodies against Epstein-Barr virus.", "content": "A practical and quantitative microtest for determination of neutralizing antibodies against Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348798"}
{"pmid": "4348799", "title": "Oncogenicity of non-transforming mutants of avian sarcoma viruses.", "content": "Oncogenicity of non-transforming mutants of avian sarcoma viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348799"}
{"pmid": "4348800", "title": "An infectious centres technique for the assay of infectious polyoma virus DNA.", "content": "An infectious centres technique for the assay of infectious polyoma virus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348800"}
{"pmid": "4348801", "title": "Comparative studies of the mitochondrial properties of Longissimus dorsi muscles of Pietrain and Large White pigs.", "content": "Comparative studies of the mitochondrial properties of Longissimus dorsi muscles of Pietrain and Large White pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348801"}
{"pmid": "4348802", "title": "The effect of diarrhoea on low density beta lipoproteins and cholesterol in protein calorie malnutrition.", "content": "The effect of diarrhoea on low density beta lipoproteins and cholesterol in protein calorie malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348802"}
{"pmid": "4348805", "title": "Low-renin hypertension.", "content": "Low-renin hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348805"}
{"pmid": "4348806", "title": "Metaplastic breast carcinoma. Rare form of mammary cancer.", "content": "Metaplastic breast carcinoma. Rare form of mammary cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348806"}
{"pmid": "4348807", "title": "Hemochromatosis, hepatoma, erythrocytosis, and erythropoietin.", "content": "Hemochromatosis, hepatoma, erythrocytosis, and erythropoietin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348807"}
{"pmid": "4348808", "title": "Gentamicin therapy for liver abscesses due to P. aeruginosa and S. marcescens.", "content": "Gentamicin therapy for liver abscesses due to P. aeruginosa and S. marcescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348808"}
{"pmid": "4348810", "title": "Ultraviolet photobleaching of free radicals created in  -irradiated amino acids.", "content": "Ultraviolet photobleaching of free radicals created in  -irradiated amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348810"}
{"pmid": "4348811", "title": "Free radicals in irradiated nitro-substituted pyrimidines.", "content": "Free radicals in irradiated nitro-substituted pyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348811"}
{"pmid": "4348812", "title": "Electron spin resonance of x-irradiated single crystals of L-threonine at 77 degrees K.", "content": "Electron spin resonance of x-irradiated single crystals of L-threonine at 77 degrees K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348812"}
{"pmid": "4348817", "title": "Effect of FSH on the in vivo uptake of  3 H-testosterone by rat seminiferous tubules.", "content": "Effect of FSH on the in vivo uptake of  3 H-testosterone by rat seminiferous tubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348817"}
{"pmid": "4348816", "title": "Investigation of the metabolism of 3-methoxy-17-epioestriol.", "content": "Investigation of the metabolism of 3-methoxy-17-epioestriol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348816"}
{"pmid": "4348818", "title": "Studies of the potency of polypeptides with ACTH action by a new method based on continuous measurement of plasma corticosterone.", "content": "Studies of the potency of polypeptides with ACTH action by a new method based on continuous measurement of plasma corticosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348818"}
{"pmid": "4348821", "title": "Mitochondrial crystals in muscles of a patient with spastic entropion.", "content": "Mitochondrial crystals in muscles of a patient with spastic entropion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348821"}
{"pmid": "4348820", "title": "Ceroid-lipofuscinosis (Batten's disease). First ophthalmological report of cytoplasmic inclusions in the Schwann's cell of the sural nerve in two patients with an amaurotic familial idiocy.", "content": "Ceroid-lipofuscinosis (Batten's disease). First ophthalmological report of cytoplasmic inclusions in the Schwann's cell of the sural nerve in two patients with an amaurotic familial idiocy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348820"}
{"pmid": "4348822", "title": "Return of goblet cells after vitamin A therapy in xerosis of the conjunctiva.", "content": "Return of goblet cells after vitamin A therapy in xerosis of the conjunctiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348822"}
{"pmid": "4348823", "title": "Hydrolytic enzyme substrates. I. Chemical synthesis and characterization.", "content": "Hydrolytic enzyme substrates. I. Chemical synthesis and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348823"}
{"pmid": "4348825", "title": "Hydrolytic enzyme substrates. 3. Phosphomonoesterase substrates.", "content": "Hydrolytic enzyme substrates. 3. Phosphomonoesterase substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348825"}
{"pmid": "4348824", "title": "Hydrolytic enzyme substrates. II. A new method for measuring periodate.", "content": "Hydrolytic enzyme substrates. II. A new method for measuring periodate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348824"}
{"pmid": "4348826", "title": "Room-temperature chromatography of nucleic acids on hydroxylapatite columns in the presence of formamide.", "content": "Room-temperature chromatography of nucleic acids on hydroxylapatite columns in the presence of formamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348826"}
{"pmid": "4348827", "title": "Predictability of response to endocrine ablation in advanced breast carcinoma. A correlation to estrogen receptor and steroid sulfurylation.", "content": "Predictability of response to endocrine ablation in advanced breast carcinoma. A correlation to estrogen receptor and steroid sulfurylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348827"}
{"pmid": "4348829", "title": "Model studies on the effects of neutral salts on the conformational stability of biological macromolecules. II. Effects of vicinal hydrophobic groups on the specificity of binding of ions to amide groups.", "content": "Model studies on the effects of neutral salts on the conformational stability of biological macromolecules. II. Effects of vicinal hydrophobic groups on the specificity of binding of ions to amide groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348829"}
{"pmid": "4348830", "title": "Model studies on the effects of neutral salts on the conformational stability of biological macromolecules. 3. Solubility of fatty acid amides in ionic solutions.", "content": "Model studies on the effects of neutral salts on the conformational stability of biological macromolecules. 3. Solubility of fatty acid amides in ionic solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348830"}
{"pmid": "4348828", "title": "Control of glucose-metabolizing enzymes in preneoplastic rat liver.", "content": "Control of glucose-metabolizing enzymes in preneoplastic rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348828"}
{"pmid": "4348831", "title": "Model studies on the effects of neutral salts on the conformational stability of biological macromolecules. IV. Properties of fatty acid amide micelles.", "content": "Model studies on the effects of neutral salts on the conformational stability of biological macromolecules. IV. Properties of fatty acid amide micelles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348831"}
{"pmid": "4348832", "title": "Interaction of an apolipoprotein (apoLP-alanine) with phosphatidylcholine.", "content": "Interaction of an apolipoprotein (apoLP-alanine) with phosphatidylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348832"}
{"pmid": "4348833", "title": "Oxidative modification of proteins in the presence of ferrous ion and air. Effect of ionic constituents of the reaction medium on the nature of the oxidation products.", "content": "Oxidative modification of proteins in the presence of ferrous ion and air. Effect of ionic constituents of the reaction medium on the nature of the oxidation products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348833"}
{"pmid": "4348834", "title": "Respiration of rat lung mitochondria and the influence of Ca 2+  on substrate utilization.", "content": "Respiration of rat lung mitochondria and the influence of Ca 2+  on substrate utilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348834"}
{"pmid": "4348836", "title": "Ionic partition between surface and bulk water in a silica gel. A biological model.", "content": "Ionic partition between surface and bulk water in a silica gel. A biological model. Distribution of the biologically important ions between two aqueous phases of different structure has been used as a model for ionic distribution in living tissue. When other sources of specificity had been eliminated or corrected for, surface-oriented water in a silica gel was found to have increased solvent power for water-structure-breaking ions and decreased solvent power for water-structure-making ions; and the relative solubility of an ion in the phase of enhanced structure increased regularly with the water-structure-breaking powers of the ion. The ionic selectivity was decreased in the presence of urea. The selectivity of the gel water for potassium relative to sodium increased to a maximum when the gel surface was partially ionized so that distribution of cations was not linked to distribution of anions, and then decreased as the surface changed from a hydrogen bonding to an ionic surface. It is pointed out that the distribution of ions across most living cell membranes is qualitatively the same as that found in this silica gel, and it is suggested that the membrane separates two aqueous phases of different structure, and that the enhanced structure of cell water contributes to the observed ionic distributions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348836"}
{"pmid": "4348837", "title": "Identification of a viral inhibitor in ground beef.", "content": "Identification of a viral inhibitor in ground beef.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348837"}
{"pmid": "4348835", "title": "Cyanogen bromide peptides from insoluble skin and dentin bovine collagens.", "content": "Cyanogen bromide peptides from insoluble skin and dentin bovine collagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348835"}
{"pmid": "4348839", "title": "Inhibition of polyoma virus development in mouse-hamster heterokaryons.", "content": "Inhibition of polyoma virus development in mouse-hamster heterokaryons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348839"}
{"pmid": "4348838", "title": "Rapid extraction and physical detection of polyoma virus.", "content": "Rapid extraction and physical detection of polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348838"}
{"pmid": "4348840", "title": "The secondary effects of sterilization of the rifampicin by gamma irradiation.", "content": "The secondary effects of sterilization of the rifampicin by gamma irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348840"}
{"pmid": "4348842", "title": "Interactions between calcium and barium on the spontaneous release of transmitter from mammalian motor nerve terminals.", "content": "Interactions between calcium and barium on the spontaneous release of transmitter from mammalian motor nerve terminals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348842"}
{"pmid": "4348843", "title": "Correlation between amplitudes and rise times of the miniature endplate potentials in frog muscle.", "content": "Correlation between amplitudes and rise times of the miniature endplate potentials in frog muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348843"}
{"pmid": "4348844", "title": "'Hallucinogenic drugs and central transmitter substances'.", "content": "'Hallucinogenic drugs and central transmitter substances'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348844"}
{"pmid": "4348845", "title": "A neural network with a background level of excitation in the cat hippocampus.", "content": "A neural network with a background level of excitation in the cat hippocampus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348845"}
{"pmid": "4348846", "title": "Interference of uranyl chloride with structure and function of molecules active at the central nervous system level.", "content": "Interference of uranyl chloride with structure and function of molecules active at the central nervous system level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348846"}
{"pmid": "4348847", "title": "Metabolite levels and enzyme activities in the bovine mammary gland at different stages of lactation. I. Metabolite levels related to energy production.", "content": "Metabolite levels and enzyme activities in the bovine mammary gland at different stages of lactation. I. Metabolite levels related to energy production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348847"}
{"pmid": "4348848", "title": "Cytomegalovirus latency in cultured human cells.", "content": "Cytomegalovirus latency in cultured human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348848"}
{"pmid": "4348849", "title": "An investigation of factors influencing the susceptibility of Balb-c 3T3 cells to polyoma virus.", "content": "An investigation of factors influencing the susceptibility of Balb-c 3T3 cells to polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348849"}
{"pmid": "4348850", "title": "Cyclic variation in susceptibility of Balb-c 3T3 cells to polyoma virus.", "content": "Cyclic variation in susceptibility of Balb-c 3T3 cells to polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348850"}
{"pmid": "4348851", "title": "The kinetics of DEAE-dextran-induced cell sensitization to transfection.", "content": "The kinetics of DEAE-dextran-induced cell sensitization to transfection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348851"}
{"pmid": "4348853", "title": "The production of infective virus by SV40-transformed human renal cells.", "content": "The production of infective virus by SV40-transformed human renal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348853"}
{"pmid": "4348852", "title": "Virus antigens on the surface of infected cells: binding and elution of ( 125 I)-labelled antivirus antibody.", "content": "Virus antigens on the surface of infected cells: binding and elution of ( 125 I)-labelled antivirus antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348852"}
{"pmid": "4348854", "title": "Distortion of poliovirus particles by fixation with formaldehyde.", "content": "Distortion of poliovirus particles by fixation with formaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348854"}
{"pmid": "4348855", "title": "Angiotensin antagonism and antihypertensive activity of phosphodiesterase inhibiting agents.", "content": "Angiotensin antagonism and antihypertensive activity of phosphodiesterase inhibiting agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348855"}
{"pmid": "4348856", "title": "The behavioral effects of dibutyryl cyclic AMP in mice.", "content": "The behavioral effects of dibutyryl cyclic AMP in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348856"}
{"pmid": "4348857", "title": "Estradiol-17 , cyclic AMP and prostaglandins: in vivo and in vitro studies on the cervicovaginal epithelium from neonatal mice.", "content": "Estradiol-17 , cyclic AMP and prostaglandins: in vivo and in vitro studies on the cervicovaginal epithelium from neonatal mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348857"}
{"pmid": "4348858", "title": "Estrogens and the menopausal patient.", "content": "Estrogens and the menopausal patient. It is noted that advertisements in medical journals recommend treatment of emotional symptoms in menopausal patients with Premarin (Ayerst brand of conjugated estrogens), Ogen (Abbott brand of piperazine estrone sulfate), or other compounds.  There are no acceptable studies proving the usefulness of such combinations for symptoms relating to the menopause and no persuasive evidence to justify use of conjugated or any other type of estrogen in the treatment of emotional symptoms in  menopausal women.  Vasomotor symptoms, flushing, and sweats respond to estrogens.  Symptoms do not recur if treatment is stopped after 1 or 2 years.  Systematic or topical use of estrogens fails to promote the appearance of youthfulness.  Vaginal pruritus and dyspareunia due to atrophic vaginitis may be relieved by estrogens either applied locally or orally.  Libido is not heightened by exogenous estrogens but sufficient androgen doses cause virilization.  It is doubtful if osteoporosis is favorably influenced by long-term use of estrogens.  Estrogen therapy may cause spotting, menarrhagia, nausea, breast tenderness, or fluid retention.  Prolonged use may cause increase in size of uterine fibroids.  Personal or even family history of breast or genital cancer are considered contraindications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348858"}
{"pmid": "4348860", "title": "Phosphodiesterase in tongue epithelium: activation by bitter taste stimuli.", "content": "Phosphodiesterase in tongue epithelium: activation by bitter taste stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348860"}
{"pmid": "4348859", "title": "Galactose metabolism and its regulation.", "content": "Galactose metabolism and its regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348859"}
{"pmid": "4348862", "title": "Subcellular distribution, age dependent variation and species differences of brain pyridoxal phosphate phosphatase.", "content": "Subcellular distribution, age dependent variation and species differences of brain pyridoxal phosphate phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348862"}
{"pmid": "4348863", "title": "Significance of clostridia in the female reproductive tract.", "content": "Significance of clostridia in the female reproductive tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348863"}
{"pmid": "4348865", "title": "Gonadotropin producing hepatoma.", "content": "Gonadotropin producing hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348865"}
{"pmid": "4348864", "title": "Effect of oral contraceptive therapy on the renin-angiotensin system in normotensive and hypertensive women.", "content": "Effect of oral contraceptive therapy on the renin-angiotensin system in normotensive and hypertensive women. Plasma renin activity, plasma renin substrate (angiotensinogen), angiotensin I (AI), and plasma angiotensinase activity were measured in 8 women who had first become hypertensive during a mean 3.1 years on various oral contraceptives, and in  5 normotensive women, before and after 1 cycle of pills.  All were determined by radioimmunoassay.  8 or more blood pressures were taken by 2 observers and averaged.  Plasma renin activity increased from mean 2.12 to 3.52 ng/ml/hr (p greater than .2) in normal women, and from 3.0 to 5.06 in hypertensives (p less than .02).  The mean plasma renin substrate values for both groups together rose from 1881 ng/ml to 4245 ng/ml.  Angiotensin I rose from .029 ng/ml/hr to .049 in normals, and .027 to .037 in hypertensives.  Mean plasma angiotensinase activity values rose from 3.6 to 5.4% degraded per minute in normal women and varied only from 6.5 before and to 5.9 after a pill cycle in hypertensive patients.  The authors suggest that development of hypertension during oral contraceptive therapy may be due to abnormal inactivation of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348864"}
{"pmid": "4348866", "title": "Malignant mixed müllerian tumor of the uterine tube.", "content": "Malignant mixed müllerian tumor of the uterine tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348866"}
{"pmid": "4348867", "title": "Granular cell myoblastoma of the vulva.", "content": "Granular cell myoblastoma of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348867"}
{"pmid": "4348868", "title": "EEG patterns in relation to respiratory rate and body movement in Macaca mulatta.", "content": "EEG patterns in relation to respiratory rate and body movement in Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348868"}
{"pmid": "4348869", "title": "Water and sodium chloride intake following microinjections of angiotensin II into the septal area of the rat brain.", "content": "Water and sodium chloride intake following microinjections of angiotensin II into the septal area of the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348869"}
{"pmid": "4348871", "title": "Effect of adrenocorticotropic hormone on appetitive discrimination learning in the rat.", "content": "Effect of adrenocorticotropic hormone on appetitive discrimination learning in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348871"}
{"pmid": "4348870", "title": "Instrumental learning without proprioceptive feedback.", "content": "Instrumental learning without proprioceptive feedback.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348870"}
{"pmid": "4348872", "title": "Arousal from sleep: responsiveness to different auditory frequencies equated for loudness.", "content": "Arousal from sleep: responsiveness to different auditory frequencies equated for loudness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348872"}
{"pmid": "4348873", "title": "Viruses of the respiratory tract.", "content": "Viruses of the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348873"}
{"pmid": "4348874", "title": "The programme of the World Health Organization in medical virology.", "content": "The programme of the World Health Organization in medical virology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348874"}
{"pmid": "4348875", "title": "Advances in the serodiagnosis of viral infections.", "content": "Advances in the serodiagnosis of viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348875"}
{"pmid": "4348876", "title": "Helper-dependent bacteriophage P4: a model satellite virus and its implications for animal virology.", "content": "Helper-dependent bacteriophage P4: a model satellite virus and its implications for animal virology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348876"}
{"pmid": "4348877", "title": "Electron microscopy of viruses in thin sections of cells grown in culture.", "content": "Electron microscopy of viruses in thin sections of cells grown in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348877"}
{"pmid": "4348878", "title": "Cytomegaloviruses of man and animals.", "content": "Cytomegaloviruses of man and animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348878"}
{"pmid": "4348887", "title": "Rectal ultrastructure in salt- and freshwater mosquito larvae in relation to physiological state.", "content": "Rectal ultrastructure in salt- and freshwater mosquito larvae in relation to physiological state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348887"}
{"pmid": "4348888", "title": "Filament bundles and contractility of endothelial cells in coronary arteries.", "content": "Filament bundles and contractility of endothelial cells in coronary arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348888"}
{"pmid": "4348891", "title": "On the regional metabolism of beef heart ventricles.", "content": "On the regional metabolism of beef heart ventricles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348891"}
{"pmid": "4348892", "title": "On the descending control of the lumbosacral spinal cord from the \"mesencephalic locomotor region\".", "content": "On the descending control of the lumbosacral spinal cord from the \"mesencephalic locomotor region\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348892"}
{"pmid": "4348889", "title": "The ultrastructure of the sinuatrial ring bundle and of the caudal extension of the sinus node in the right atrium of the rabbit heart.", "content": "The ultrastructure of the sinuatrial ring bundle and of the caudal extension of the sinus node in the right atrium of the rabbit heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348889"}
{"pmid": "4348893", "title": "Estrogen for older women.", "content": "Estrogen for older women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348893"}
{"pmid": "4348894", "title": "Some pathologic and biochemical aspects of Coats' disease.", "content": "Some pathologic and biochemical aspects of Coats' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348894"}
{"pmid": "4348895", "title": "Conservative management of congenital eversion of the eyelids.", "content": "Conservative management of congenital eversion of the eyelids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348895"}
{"pmid": "4348899", "title": "The structure of a lipid-cytochrome c membrane.", "content": "The structure of a lipid-cytochrome c membrane. In the preceding paper a theory has been developed for the X-ray diffraction pattern from a lipid bilayer coated with protein molecules. In this paper the validity of the theory is tested. After adding cytochrome c to a preparation of lipid vesicles both vesicles and, in lesser amount, a multilayered structure are found. The expected cross-interference ripple is evident, and a computed profile shows the added protein at the surface of an unchanged lipid bilayer. The results confirm the structure proposed by others on the basis of rather indirect chemical and X-ray data. Protein coating a lipid bilayer is a possible structure for natural membranes. These results demonstrate that globular protein molecules can be detected at the surfaces of a lipid bilayer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348899"}
{"pmid": "4348900", "title": "Striate-peristriate cortico-cortical connections in the albino and gray rat.", "content": "Striate-peristriate cortico-cortical connections in the albino and gray rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348900"}
{"pmid": "4348901", "title": "Patterns of degeneration after intrinsic lesions of the visual cortex (area 17) of the monkey.", "content": "Patterns of degeneration after intrinsic lesions of the visual cortex (area 17) of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348901"}
{"pmid": "4348902", "title": "Descending influences on spinocervical tract cell discharges evoked by non-myelinated cutaneous afferent nerve fibres.", "content": "Descending influences on spinocervical tract cell discharges evoked by non-myelinated cutaneous afferent nerve fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348902"}
{"pmid": "4348903", "title": "Interactions of cutaneous myelinated (A) and non-myelinated (C) fibres on transmission through the spinocervical tract.", "content": "Interactions of cutaneous myelinated (A) and non-myelinated (C) fibres on transmission through the spinocervical tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348903"}
{"pmid": "4348904", "title": "Effect of calcium and magnesium on spontaneous transmitter release accelerated by raised potassium.", "content": "Effect of calcium and magnesium on spontaneous transmitter release accelerated by raised potassium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348904"}
{"pmid": "4348905", "title": "Accumulation of adenosine 3',5'-monophosphate induced by catecholamines in the rat superior cervical ganglion in vitro.", "content": "Accumulation of adenosine 3',5'-monophosphate induced by catecholamines in the rat superior cervical ganglion in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348905"}
{"pmid": "4348910", "title": "Serum magnesium, serum cholesterol and serum lipoproteins in cases of coronary artery disease.", "content": "Serum magnesium, serum cholesterol and serum lipoproteins in cases of coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348910"}
{"pmid": "4348911", "title": "Some subcortical determinants of visual cortical excitability in the cat.", "content": "Some subcortical determinants of visual cortical excitability in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348911"}
{"pmid": "4348912", "title": "The effect of pertinent and non-pertinent stimuli on the secretions on thyrotropin and corticotropin.", "content": "The effect of pertinent and non-pertinent stimuli on the secretions on thyrotropin and corticotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348912"}
{"pmid": "4348913", "title": "Platelet aggregation in atopic and normal patients.", "content": "Platelet aggregation in atopic and normal patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348913"}
{"pmid": "4348914", "title": "Effect of training on enzyme activity and fiber composition of human skeletal muscle.", "content": "Effect of training on enzyme activity and fiber composition of human skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348914"}
{"pmid": "4348915", "title": "A comparison of the major apolipoprotein from pig and human high density lipoproteins.", "content": "A comparison of the major apolipoprotein from pig and human high density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348915"}
{"pmid": "4348916", "title": "The purine nucleotide cycle. 3. Oscillations in metabolite concentrations during the operation of the cycle in muscle extracts.", "content": "The purine nucleotide cycle. 3. Oscillations in metabolite concentrations during the operation of the cycle in muscle extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348916"}
{"pmid": "4348917", "title": "Stimulation of steroid secretion by antimicrotubular agents.", "content": "Stimulation of steroid secretion by antimicrotubular agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348917"}
{"pmid": "4348919", "title": "Enzymes of pentose biosynthesis. II. Evidence that the proposed control of glucose 6-phosphate dehydrogenase by reduced diphosphopyridine nucleotide is an instrumental artifact.", "content": "Enzymes of pentose biosynthesis. II. Evidence that the proposed control of glucose 6-phosphate dehydrogenase by reduced diphosphopyridine nucleotide is an instrumental artifact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348919"}
{"pmid": "4348918", "title": "Adenosine 3',5'-monophosphate in glial tumor cells. Alterations by 5-bromodeoxyuridine.", "content": "Adenosine 3',5'-monophosphate in glial tumor cells. Alterations by 5-bromodeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348918"}
{"pmid": "4348921", "title": "The mechanism of action of the flavoprotein melilotate hydroxylase.", "content": "The mechanism of action of the flavoprotein melilotate hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348921"}
{"pmid": "4348920", "title": "The purification and properties of the flavoprotein melilotate hydroxylase.", "content": "The purification and properties of the flavoprotein melilotate hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348920"}
{"pmid": "4348922", "title": "Pituitary-adrenal interaction and growth of the embryonic avian adrenal gland.", "content": "Pituitary-adrenal interaction and growth of the embryonic avian adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348922"}
{"pmid": "4348923", "title": "Fibrous histiocytoma or xanthoma of the lung with bronchial involvement.", "content": "Fibrous histiocytoma or xanthoma of the lung with bronchial involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348923"}
{"pmid": "4348924", "title": "The role of specific IgM globulin estimations in the diagnosis of acquired rubella.", "content": "The role of specific IgM globulin estimations in the diagnosis of acquired rubella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348924"}
{"pmid": "4348925", "title": "Systemic corticosteroid therapy.", "content": "Systemic corticosteroid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348925"}
{"pmid": "4348926", "title": "Characterization of chemically induced mutations in the ad-I locus of Schizosaccharomyces pombe.", "content": "Characterization of chemically induced mutations in the ad-I locus of Schizosaccharomyces pombe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348926"}
{"pmid": "4348927", "title": "Genetic analysis of purple adenine (ad-3) mutants induced by methyl methanesulfonate in Neurospora crassa.", "content": "Genetic analysis of purple adenine (ad-3) mutants induced by methyl methanesulfonate in Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348927"}
{"pmid": "4348928", "title": "Production of cyclic inositol phosphate in stimulated tissues.", "content": "Production of cyclic inositol phosphate in stimulated tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348928"}
{"pmid": "4348929", "title": "Levels of cyclic AMP in sparse and dense cultures of growing and quiescent 3T3 cells.", "content": "Levels of cyclic AMP in sparse and dense cultures of growing and quiescent 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348929"}
{"pmid": "4348930", "title": "Cyclic AMP and growth of fibroblasts: effect of environmental pH.", "content": "Cyclic AMP and growth of fibroblasts: effect of environmental pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348930"}
{"pmid": "4348936", "title": "Cylindroma of the sphenoid sinus. A study of two cases.", "content": "Cylindroma of the sphenoid sinus. A study of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348936"}
{"pmid": "4348937", "title": "Bovine virus diarrhea associated with severe pneumotropism.", "content": "Bovine virus diarrhea associated with severe pneumotropism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348937"}
{"pmid": "4348938", "title": "Biochemical lesions of respiratory enzymes and configurational changes of mitochondria in vivo. I. The effect of fluoroacetate: a study by phase-contrast microscopy and time-lapse cinemicrography.", "content": "Biochemical lesions of respiratory enzymes and configurational changes of mitochondria in vivo. I. The effect of fluoroacetate: a study by phase-contrast microscopy and time-lapse cinemicrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348938"}
{"pmid": "4348939", "title": "A radioautographic study of the transport of  125 I-labeled serum lipoproteins in rat aorta.", "content": "A radioautographic study of the transport of  125 I-labeled serum lipoproteins in rat aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348939"}
{"pmid": "4348942", "title": "Quantitative correlation of plasma and myocardial quinidine concentrations with biochemical and electrocardiographic changes.", "content": "Quantitative correlation of plasma and myocardial quinidine concentrations with biochemical and electrocardiographic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348942"}
{"pmid": "4348934", "title": "Some factors controlling the secretion of antidiuretic hormone and renin.", "content": "Some factors controlling the secretion of antidiuretic hormone and renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348934"}
{"pmid": "4348944", "title": "Bronchioloalveolar carcinoma. Clinicopathologic relationships, natural history, and prognosis in 29 cases.", "content": "Bronchioloalveolar carcinoma. Clinicopathologic relationships, natural history, and prognosis in 29 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348944"}
{"pmid": "4348943", "title": "Altered morphology and increased acid hydrolase content of pulmonary macrophages from cigarette smokers.", "content": "Altered morphology and increased acid hydrolase content of pulmonary macrophages from cigarette smokers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348943"}
{"pmid": "4348945", "title": "Effect of pyrazinamide on nicotinamide adenine dinucleotide glycohydrolase of tuberculous host.", "content": "Effect of pyrazinamide on nicotinamide adenine dinucleotide glycohydrolase of tuberculous host.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348945"}
{"pmid": "4348946", "title": "Alveolar cell carcinoma. Diagnosis by lobar lavage.", "content": "Alveolar cell carcinoma. Diagnosis by lobar lavage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348946"}
{"pmid": "4348947", "title": "Effects of pneumonia on intrapulmonary distribution of inhaled particles.", "content": "Effects of pneumonia on intrapulmonary distribution of inhaled particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348947"}
{"pmid": "4348949", "title": "Multiple cylindromas.", "content": "Multiple cylindromas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348949"}
{"pmid": "4348948", "title": "Treating friction blisters with alkyl- -cyanoacrylates.", "content": "Treating friction blisters with alkyl- -cyanoacrylates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348948"}
{"pmid": "4348950", "title": "Carcinoma of mammary crease \"simulating basal cell epithelioma\".", "content": "Carcinoma of mammary crease \"simulating basal cell epithelioma\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348950"}
{"pmid": "4348956", "title": "Para-fluorophenylalanine as an inhibitor of parainfluenza 3 virus multiplication.", "content": "Para-fluorophenylalanine as an inhibitor of parainfluenza 3 virus multiplication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348956"}
{"pmid": "4348957", "title": "Differences between B. pertussis and propranolol induced histamine hypersensitivity in mice.", "content": "Differences between B. pertussis and propranolol induced histamine hypersensitivity in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348957"}
{"pmid": "4348958", "title": "I. Pharmacology of angiotensin antagonists.", "content": "I. Pharmacology of angiotensin antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348958"}
{"pmid": "4348959", "title": "II. Pharmacology of angiotensin antagonists.", "content": "II. Pharmacology of angiotensin antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348959"}
{"pmid": "4348960", "title": "Inactivation of exogenous and neural noradrenaline by elastic and muscular arteries.", "content": "Inactivation of exogenous and neural noradrenaline by elastic and muscular arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348960"}
{"pmid": "4348961", "title": "Some aspects of sarcoidosis.", "content": "Some aspects of sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348961"}
{"pmid": "4348962", "title": "Hydroxyproline-rich wall protein (extensin): biosynthesis and accumulation in growing pea epicotyls.", "content": "Hydroxyproline-rich wall protein (extensin): biosynthesis and accumulation in growing pea epicotyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348962"}
{"pmid": "4348952", "title": "Reticuloendotheliosis virus (strain T). VI. An immunogen versus reticuloendotheliosis and Rous sarcoma.", "content": "Reticuloendotheliosis virus (strain T). VI. An immunogen versus reticuloendotheliosis and Rous sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348952"}
{"pmid": "4348954", "title": "Studies on fowlpox viruses. I. Plaque formation of fowlpox virus on chick embryo cell culture.", "content": "Studies on fowlpox viruses. I. Plaque formation of fowlpox virus on chick embryo cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348954"}
{"pmid": "4348953", "title": "Avian encephalomyelitis: pathogenesis and histologic features of dorsal root ganglia lesions in chicks.", "content": "Avian encephalomyelitis: pathogenesis and histologic features of dorsal root ganglia lesions in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348953"}
{"pmid": "4348963", "title": "Increased toxicity of double-stranded ribonucleic acid in virus-infected animals.", "content": "Increased toxicity of double-stranded ribonucleic acid in virus-infected animals. Virus-infected mice were significantly more susceptible to the toxic effects of double-stranded ribonucleic acid (RNA) than uninfected mice. A dramatic increase in mortality was observed after injection of either synthetic (polyriboinosinic.polyribocytidylic acid) or natural (mycophage) double-stranded RNA in mice infected with Newcastle disease virus (NDV) or vesicular stomatitis virus (VSV). With the exception of endotoxin, interferon inducers other than double-stranded RNA, such as tilorone-hydrochloride and chlorite-oxidized oxyamylose, did not show this increased toxicity in virus-infected animals. The increased susceptibility of virus-infected animals to the toxic effects of double-stranded RNA appears to be related to the levels of interferon induced by the virus infection, either systemically, in the blood stream (after inoculation of NDV), or locally, in the brain (after infection with VSV).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348963"}
{"pmid": "4348955", "title": "Studies on fowlpox viruses. II. Plaque-neutralization test.", "content": "Studies on fowlpox viruses. II. Plaque-neutralization test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348955"}
{"pmid": "4348964", "title": "Enhancement, by two carboxylic acid interferon inducers of resistance stimulated in mice by foot-and-mouth disease vaccine.", "content": "Enhancement, by two carboxylic acid interferon inducers of resistance stimulated in mice by foot-and-mouth disease vaccine. Simultaneous injection of divinyl ether-maleic amhydride (DVE/MA) or itaconic-acrylic acid and foot-and-mouth disease virus vaccine enhanced the survival of infant mice to subsequent injections of virus. This enhanced resistance was obtained even with doses of interferon inducers which, when administered alone, failed to protect the mice. There was some increase in serum-neutralizing antibody in mice 7 days after injection of DVE/MA and vaccine, as compared with mice given vaccine alone, but there was no clear connection between antibody level and amount of DVE/MA administered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348964"}
{"pmid": "4348965", "title": "In vivo studies with collagenase from Pseudomonas aeruginosa.", "content": "In vivo studies with collagenase from Pseudomonas aeruginosa. An extracellular protease from Pseudomonas aeruginosa having collagenase activity was assayed in vivo. The lethality of the enzyme for white female mice was determined by use of intravenous, intraperitoneal, intranasal, and subcutaneous routes, respectively. The collagenase exhibited the following 72-hr mean lethal dose values: intranasally, 55 collagenase units; intraperitoneally, 148 collagenase units; and intravenously, 288 collagenase units. In the concentrations tested, no lethality was obtained when the subcutaneous route was employed. Gross and microscopic studies revealed that the collagenase was capable of eliciting a variety of tissue responses in mice depending upon its route of administration. Intranasal instillation resulted in confluent pulmonary hemorrhage, whereas intraperitoneal injections resulted in severe abdominal hemorrhage with foci on the intestinal serosa. Intravenous injections elicited abdominal hemorrhage and petechial hemorrhage with focal necrosis of the lungs, whereas subcutaneous injections resulted in necrotic, ulcerating lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348965"}
{"pmid": "4348966", "title": "Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport of infection.", "content": "Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport of infection. The pathogenesis of acute herpetic infection in the nervous system has been studied following rear footpad inoculation of mice. Viral assays performed on appropriate tissues at various time intervals indicated that the infection progressed sequentially from peripheral to the central nervous system, with infectious virus reaching the sacrosciatic spinal ganglia in 20 to 24 hr. The infection also progressed to ganglia in mice given high levels of anti-viral antibody. Immunofluorescent techniques demonstrated that both neurons and supporting cells produced virus-specific antigens. By electron microscopy, neurons were found to produce morphologically complete virions, but supporting cells replicated principally nucleocapsids. These results are discussed in the context of possible mechanisms by which herpes simplex virus might travel in nerve trunks. They are considered to offer strong support for centripetal transport in axons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348966"}
{"pmid": "4348967", "title": "Assay of cortisol, corticosterone, 11-deoxycortisol and cortisone in ovine peripheral and adrenal venous plasma.", "content": "Assay of cortisol, corticosterone, 11-deoxycortisol and cortisone in ovine peripheral and adrenal venous plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348967"}
{"pmid": "4348968", "title": "Distribution of adrenocorticotrophic hormone-stimulated adenylate cyclase in the adrenal cortex.", "content": "Distribution of adrenocorticotrophic hormone-stimulated adenylate cyclase in the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348968"}
{"pmid": "4348969", "title": "Morphological responses to corticotrophin and cyclic AMP by adult rat adrenocortical cells in monolayer culture.", "content": "Morphological responses to corticotrophin and cyclic AMP by adult rat adrenocortical cells in monolayer culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348969"}
{"pmid": "4348970", "title": "The steroidogenic response of adult rat adrenocortical cells in monolayer culture.", "content": "The steroidogenic response of adult rat adrenocortical cells in monolayer culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348970"}
{"pmid": "4348971", "title": "A comparison of procedures for the isolation of adrenocorticotrophin from human pituitary glands.", "content": "A comparison of procedures for the isolation of adrenocorticotrophin from human pituitary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348971"}
{"pmid": "4348972", "title": "Virus-like particles associated with the mycoplasmas of clover phyllody in the plant and in the insect vector.", "content": "Virus-like particles associated with the mycoplasmas of clover phyllody in the plant and in the insect vector.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348972"}
{"pmid": "4348974", "title": "Lymphocyte activation. 3. The prolonged requirement for mitogen in phytohaemagglutinin- and concanavalin A-stimulated cultures.", "content": "Lymphocyte activation. 3. The prolonged requirement for mitogen in phytohaemagglutinin- and concanavalin A-stimulated cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348974"}
{"pmid": "4348973", "title": "Decline in mixed lymphocyte reactivity of spleen cells from aged mice of a long-lived strain.", "content": "Decline in mixed lymphocyte reactivity of spleen cells from aged mice of a long-lived strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348973"}
{"pmid": "4348976", "title": "Oat cell carcinoma of bronchus associated with carcinoid syndrome and intestinal carcinoid.", "content": "Oat cell carcinoma of bronchus associated with carcinoid syndrome and intestinal carcinoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348976"}
{"pmid": "4348977", "title": "Congenital epulis.", "content": "Congenital epulis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348977"}
{"pmid": "4348975", "title": "Host defenses during primary Venezuelan equine encephalomyelitis virus infection in mice. I. Passive transfer of protection with immune serum and immune cells.", "content": "Host defenses during primary Venezuelan equine encephalomyelitis virus infection in mice. I. Passive transfer of protection with immune serum and immune cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348975"}
{"pmid": "4348978", "title": "Cervical cancer.", "content": "Cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348978"}
{"pmid": "4348979", "title": "Development and characteristics of the histamine-induced accumulation of cyclic AMP in the rabbit cerebral cortex.", "content": "Development and characteristics of the histamine-induced accumulation of cyclic AMP in the rabbit cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348979"}
{"pmid": "4348980", "title": "Modulators of glutaminase activity.", "content": "Modulators of glutaminase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348980"}
{"pmid": "4348981", "title": "Purification and characterization of an NADH-linked aldehyde reductase from bovine brain.", "content": "Purification and characterization of an NADH-linked aldehyde reductase from bovine brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348981"}
{"pmid": "4348982", "title": "Distribution and properties of angiotensin converting enzyme of rat brain.", "content": "Distribution and properties of angiotensin converting enzyme of rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348982"}
{"pmid": "4348983", "title": "Angiotensinase activity in rat and dog brain.", "content": "Angiotensinase activity in rat and dog brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348983"}
{"pmid": "4348984", "title": "An ATP pool associated with adenyl cyclase of brain tissue.", "content": "An ATP pool associated with adenyl cyclase of brain tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348984"}
{"pmid": "4348986", "title": "Serum inhibitors of A 2 -Hong Kong influenza virus haemagglutination.", "content": "Serum inhibitors of A 2 -Hong Kong influenza virus haemagglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348986"}
{"pmid": "4348987", "title": "Interaction of Sendai virus with human erythrocytes: a system for the study of membrane fusion.", "content": "Interaction of Sendai virus with human erythrocytes: a system for the study of membrane fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348987"}
{"pmid": "4348988", "title": "Lung cancer in chloromethyl methyl ether workers.", "content": "Lung cancer in chloromethyl methyl ether workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348988"}
{"pmid": "4348989", "title": "Viral infections and demyelinating diseases.", "content": "Viral infections and demyelinating diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348989"}
{"pmid": "4348990", "title": "Treatment of tuberculosis today in Nebraska.", "content": "Treatment of tuberculosis today in Nebraska.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348990"}
{"pmid": "4348995", "title": "Responsivity in infants during sleep.", "content": "Responsivity in infants during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348995"}
{"pmid": "4348996", "title": "Cerebral responses to flickering light in clinical research.", "content": "Cerebral responses to flickering light in clinical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348996"}
{"pmid": "4348997", "title": "Effect of diphenylhydantoin on paroxysmal EEG activity induced by cortical cobalt focus.", "content": "Effect of diphenylhydantoin on paroxysmal EEG activity induced by cortical cobalt focus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348997"}
{"pmid": "4348998", "title": "Diagnosis and management of hyperlipoproteinemia in infants and children.", "content": "Diagnosis and management of hyperlipoproteinemia in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348998"}
{"pmid": "4348999", "title": "Pressure reversal of anesthesia: the extent of small-molecule exclusion from spin-labeled phospholipid model membranes.", "content": "Pressure reversal of anesthesia: the extent of small-molecule exclusion from spin-labeled phospholipid model membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4348999"}
{"pmid": "4349000", "title": "The electromyogram and the mechanical response of indirectly stimulated muscle in anesthetized man following curarization.", "content": "The electromyogram and the mechanical response of indirectly stimulated muscle in anesthetized man following curarization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349000"}
{"pmid": "4349001", "title": "Covalent and noncovalent control of glycogen synthesis.", "content": "Covalent and noncovalent control of glycogen synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349001"}
{"pmid": "4349002", "title": "Glycogen metabolism during differentiation in Dictyostelium discoideum.", "content": "Glycogen metabolism during differentiation in Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349002"}
{"pmid": "4349004", "title": "Factors determining colony forming efficiency in agar suspension cultures.", "content": "Factors determining colony forming efficiency in agar suspension cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349004"}
{"pmid": "4349003", "title": "Preliminary studies of the neurones of Auerbach's plexus using intracellular microelectrodes.", "content": "Preliminary studies of the neurones of Auerbach's plexus using intracellular microelectrodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349003"}
{"pmid": "4349005", "title": "The structure and function of adrenal autotransplants.", "content": "The structure and function of adrenal autotransplants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349005"}
{"pmid": "4349006", "title": "On the neuronal organization of the acoustic middle ear reflex. A physiological and anatomical study.", "content": "On the neuronal organization of the acoustic middle ear reflex. A physiological and anatomical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349006"}
{"pmid": "4349007", "title": "Quantitative neural and psychophysical data for cutaneous mechanoreceptor function.", "content": "Quantitative neural and psychophysical data for cutaneous mechanoreceptor function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349007"}
{"pmid": "4349008", "title": "Nature of the midbrain influences upon thalamic neurons.", "content": "Nature of the midbrain influences upon thalamic neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349008"}
{"pmid": "4349009", "title": "The quantitative relation between extracellular calcium and acetylcholine release at the frog neuromuscular junction.", "content": "The quantitative relation between extracellular calcium and acetylcholine release at the frog neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349009"}
{"pmid": "4349010", "title": "A comparison of the binding of ( 14 C) -aminobutyric acid and ( 3 H)acetylcholine to particulate fractions of 4 regions of rat brain in the presence of 40 mM NaCl.", "content": "A comparison of the binding of ( 14 C) -aminobutyric acid and ( 3 H)acetylcholine to particulate fractions of 4 regions of rat brain in the presence of 40 mM NaCl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349010"}
{"pmid": "4349011", "title": "A possible role for mast cells in controlling the diameter of arterioles on the surface of the brain.", "content": "A possible role for mast cells in controlling the diameter of arterioles on the surface of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349011"}
{"pmid": "4349012", "title": "Dynamic single unit simulation of a realistic cerebellar network model.", "content": "Dynamic single unit simulation of a realistic cerebellar network model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349012"}
{"pmid": "4349013", "title": "Periodate-induced lymphocyte transformation. II. Character of response and comparison with phytohemagglutinin and pokeweed mitogen stimulation.", "content": "Periodate-induced lymphocyte transformation. II. Character of response and comparison with phytohemagglutinin and pokeweed mitogen stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349013"}
{"pmid": "4349014", "title": "The study of cellular \"microexudates\" by ellipsometry and their relationship to the cell coat.", "content": "The study of cellular \"microexudates\" by ellipsometry and their relationship to the cell coat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349014"}
{"pmid": "4349015", "title": "Use of a serum gradient for separation of polykaryocytes from single cells after fusion with Sendai virus.", "content": "Use of a serum gradient for separation of polykaryocytes from single cells after fusion with Sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349015"}
{"pmid": "4349017", "title": "Morphology and growth rate changes in Chinese hamster cells cultured in presence of sodium butyrate.", "content": "Morphology and growth rate changes in Chinese hamster cells cultured in presence of sodium butyrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349017"}
{"pmid": "4349016", "title": "Comparative effects of caffeine, its analogues and calcium deficiency on cytokinesis.", "content": "Comparative effects of caffeine, its analogues and calcium deficiency on cytokinesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349016"}
{"pmid": "4349018", "title": "Inhibition of DNA synthesis of synchronized cells by liver extracts acting in G1 phase.", "content": "Inhibition of DNA synthesis of synchronized cells by liver extracts acting in G1 phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349018"}
{"pmid": "4349019", "title": "Resistance of amoeba cytoplasm to cycloheximide.", "content": "Resistance of amoeba cytoplasm to cycloheximide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349019"}
{"pmid": "4349021", "title": "Cyclic AMP of blood platelets: accumulation in organelles storing 5-hydroxytryptamine and ATP.", "content": "Cyclic AMP of blood platelets: accumulation in organelles storing 5-hydroxytryptamine and ATP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349021"}
{"pmid": "4349020", "title": "Release of fibrinolytic activators from human tumours cultured in vitro.", "content": "Release of fibrinolytic activators from human tumours cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349020"}
{"pmid": "4349022", "title": "Cyclic AMP: its effect on an estrogen-sensitive antigen in organ cultures of the cervicovaginal epithelium from neonatal mice.", "content": "Cyclic AMP: its effect on an estrogen-sensitive antigen in organ cultures of the cervicovaginal epithelium from neonatal mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349022"}
{"pmid": "4349023", "title": "Possible role of glucose-6-phosphate in the anti-anaphylactic mechanism mediated by cyclic AMP.", "content": "Possible role of glucose-6-phosphate in the anti-anaphylactic mechanism mediated by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349023"}
{"pmid": "4349024", "title": "A roentgenometric study of the process of ossification of the human sternum.", "content": "A roentgenometric study of the process of ossification of the human sternum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349024"}
{"pmid": "4349025", "title": "A new analysis of neuronal interspike intervals based on inequality tests.", "content": "A new analysis of neuronal interspike intervals based on inequality tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349025"}
{"pmid": "4349026", "title": "A multistage transduction model for information processing in the nervous system.", "content": "A multistage transduction model for information processing in the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349026"}
{"pmid": "4349027", "title": "Recognition of a gene involved in the regulation of nicotinamide adenine dinucleotide biosynthesis.", "content": "Recognition of a gene involved in the regulation of nicotinamide adenine dinucleotide biosynthesis. Mutations affecting the biosynthesis of quinolinic acid, a precursor of nicotinamide adenine dinucleotide (NAD) in Escherichia coli K-12, are either near min 17 (nadA mutants) or near min 49 on the chromosome. These nad mutants all exhibit a phenotypic requirement for NAD or one of its immediate precursors. The mutants with lesions near min 49 can be separated into two groups based on in vitro complementation analysis. One group (nadB) exhibits complementation with nadA mutants, whereas the other group fails to do so. The latter group is tentatively designated nadR based on its regulation of the unlinked nadA gene. The nadR gene maps adjacent to nadB between purI and tyrA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349027"}
{"pmid": "4349028", "title": "Selection of respiratory mutants of Neurospora crassa.", "content": "Selection of respiratory mutants of Neurospora crassa. A method is described that permits the isolation of mutants that are defective in mitochondrial respiration. The techniques of inositol-less death and overlay with 2,3,5-triphenyl-2H-tetrazolium chloride are utilized to select for mutant colonies. Colonies that survive inositol-less death and fail to reduce the tetrazolium dye are then tested polarographically for cyanide-sensitive respiration. A preliminary characterization of three mutants obtained by this method is presented. The mutants have been characterized by their cyanide-sensitive respiration rate, growth rate, the state III respiration rate of isolated mitochondria, inhibition of the respiration of isolated mitochondria by cyanide and antimycin A, and cytochrome spectra. All of the mutants described differ from the parent strain in some of these aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349028"}
{"pmid": "4349029", "title": "Saccharomyces mutants with invertase formation resistant to repression by hexoses.", "content": "Saccharomyces mutants with invertase formation resistant to repression by hexoses. Production of invertase by many strains of yeast is repressed in the presence of hexoses. This phenomenon interferes with studies on the secretion of invertase and with the preparation of large quantities of the enzyme for examination of its chemical and physical characteristics. Saccharomyces strain 303-67, a diploid carrying the single gene SUC-2 for (hexose repressible) invertase production, was subjected to ultraviolet irradiation. No single-step mutations to high level resistance were detected. By a two-step irradiation process mutants were obtained with differing degrees of resistance. The biochemical and genetic characteristics of these mutants are summarized with particular emphasis on FH4C (the most resistant). Although the steady state level of cyclic 3', 5'-adenosine monophosphate (cyclic AMP) was usually slightly higher in cells grown in low- rather than in high-glucose media, the level of cyclic AMP was not correlated with the sensitivity of invertase synthesis to glucose repression. In mutant FH4C, 1 to 2% of the total cell protein is present as invertase; synthesis of alpha-glucosidase is also resistant to repression by hexoses. This mutant does not sporulate and is probably a haploid of a-mating type with low frequency of conjugation and poor viability of conjugants. Mutants 1016 and 1710 are substantially resistant to hexose repression and still sporulate well. They may be useful for genetic analysis of hexose resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349029"}
{"pmid": "4349030", "title": "Physiological modifications in the production and repair of methyl methane sulfonate-induced breaks in the deoxyribonucleic acid of Escherichia coli K-12.", "content": "Physiological modifications in the production and repair of methyl methane sulfonate-induced breaks in the deoxyribonucleic acid of Escherichia coli K-12. The medium in which Rec(+) strains of Escherichia coli K-12 are grown affected their sensitivity to treatment with methyl methane sulfonate (MMS). Rec(+) cells grown to the stationary phase in glucose-enriched nutrient broth (GNB) were more resistant to MMS than cells grown in nutrient broth (NB). The repair of MMS-induced breaks (or alkali-labile bonds) in the deoxyribonucleic acid (DNA) from E. coli K-12 strains AB1157, AB1886 uvrA6, and SR111 recA13 recB21 grown in GNB and NB media was examined by means of alkaline sucrose gradient centrifugation. It appeared that essentially all of the repair of breaks that occurred, as evidenced by an increase in \"molecular weight,\" took place within 10 min after treatment with MMS under our conditions. Cell survival was highest in cells for which the size of the DNA after the post-treatment incubation was the largest. The largest DNA after post-treatment incubation was found in Rec(+) cells grown in GNB medium. The results suggest that these cells may have an enhanced capacity for repairing breaks in DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349030"}
{"pmid": "4349031", "title": "Fate of transforming deoxyribonucleic acid after uptake by competent Bacillus subtilis: phenotypic characterization of radiation-sensitive recombination-deficient mutants.", "content": "Fate of transforming deoxyribonucleic acid after uptake by competent Bacillus subtilis: phenotypic characterization of radiation-sensitive recombination-deficient mutants. A collection of 16 isogenic recombination-deficient strains of Bacillus subtilis isolated on the basis of sensitivity to methyl methane sulfonate (MMS) or mitomycin C (MC) were characterized phenotypically. All were found to be somewhat sensitive to ultraviolet irradiation, MC, and MMS. The mutants were all blocked in \"late\" steps in the transformation process and were provisionally grouped into four categories on the basis of the various properties examined. Class I mutants were deficient in transformation and heterologous transduction with phage PBS1 but were transducible with homologous donors at nearly the wild-type frequency. They were blocked in donor-recipient complex (DRC) formation but formed essentially normal amounts of double-strand fragments (DSF) and single-strand fragments (SSF). The class IIa strain was deficient in transformation and PBS1 transduction, and formed DRC which was normal by all available physical and biological criteria. Class IIb mutants were deficient in transformation and PBS1 transduction, and failed to form DRC. They did produce DSF and SSF. Class III mutants were deficient in transformation, were normal in PBS1 transduction, and formed DRC which was physically indistinguishable from that of the Rec(+) parent although with slightly lowered donor-type transforming activity. Class IV strains were deficient in PBS1 transduction but were transformed at nearly the wild-type efficiency. None of the mutant strains was deficient in the adenosine triphosphate-dependent deoxyribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349031"}
{"pmid": "4349032", "title": "Methanol metabolism in pseudomonad C.", "content": "Methanol metabolism in pseudomonad C. Cell suspensions of pseudomonad C, a bacterium capable of growth on methanol as sole carbon source, were able to oxidize methanol, formaldehyde, and formate, although the rates of oxidation for the latter two compounds were much slower. The latter compounds also could not serve as sole carbon sources. Through the use of labeled compounds, it was shown that in the presence of methanol, formaldehyde, formate, and bicarbonate were incorporated into trichloroacetic acid-precipitable material. Hexose phosphate synthetase activity was found, indicating the assimilation of methanol via an allulose pathway. No hydroxypyruvate reductase activity was found, nor was any complex membrane structure observed. Such a combination of characteristics has been observed in an obligate methylotroph (Pseudomonas W1), but pseudomonad C can utilize a variety of non-methyl substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349032"}
{"pmid": "4349033", "title": "CO 2  reduction to formate in Clostridium acidi-urici.", "content": "CO 2  reduction to formate in Clostridium acidi-urici. Cell-free lysates of Clostridium acidi-urici catalyze the reduction of CO(2) to formate in the presence of reduced ferredoxin and nicotinamide adenine dinucleotide, reduced form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349033"}
{"pmid": "4349034", "title": "Oligosaccharides produced by acetolysis of blood group active(A + H)sulfated glycoproteins from hog gastric mucin.", "content": "Oligosaccharides produced by acetolysis of blood group active(A + H)sulfated glycoproteins from hog gastric mucin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349034"}
{"pmid": "4349035", "title": "The crystal structure of a riboflavin-metal complex. Ribofalavin silver perchlorate hemihydrate.", "content": "The crystal structure of a riboflavin-metal complex. Ribofalavin silver perchlorate hemihydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349035"}
{"pmid": "4349036", "title": "Kinetics of the glucose 6-phosphate-glucose exchange activity and glucose inhibition of glucose 6-phosphatase of intact and disrupted rat liver microsomes.", "content": "Kinetics of the glucose 6-phosphate-glucose exchange activity and glucose inhibition of glucose 6-phosphatase of intact and disrupted rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349036"}
{"pmid": "4349037", "title": "Evaluation of the rate-determining steps and the relative magnitude of the individual rate constants for the hydrolytic and synthetic activities of the catalytic component of liver microsomal glucose 6-phosphatase.", "content": "Evaluation of the rate-determining steps and the relative magnitude of the individual rate constants for the hydrolytic and synthetic activities of the catalytic component of liver microsomal glucose 6-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349037"}
{"pmid": "4349038", "title": "Steroidogenesis and cyclic adenosine 3',5'-monophosphate accumulation in rat adrenal cells. Divergent effects of adrenocorticotropin and its o-nitrophenyl sulfenyl derivative.", "content": "Steroidogenesis and cyclic adenosine 3',5'-monophosphate accumulation in rat adrenal cells. Divergent effects of adrenocorticotropin and its o-nitrophenyl sulfenyl derivative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349038"}
{"pmid": "4349039", "title": "Human adenine phosphoribosyltransferase. Purification, subunit structure, and substrate specificity.", "content": "Human adenine phosphoribosyltransferase. Purification, subunit structure, and substrate specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349039"}
{"pmid": "4349040", "title": "Mitochondrial D- -hydroxybutyrate dehydrogenase. IV. Kinetic analysis of reaction mechanism.", "content": "Mitochondrial D- -hydroxybutyrate dehydrogenase. IV. Kinetic analysis of reaction mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349040"}
{"pmid": "4349041", "title": "Mitochondrial-cytosolic interactions in perfused rat heart. Role of coupled transamination in repletion of citric acid cycle intermediates.", "content": "Mitochondrial-cytosolic interactions in perfused rat heart. Role of coupled transamination in repletion of citric acid cycle intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349041"}
{"pmid": "4349042", "title": "Some properties of the catalytic sites of imidazoleglycerol phosphate dehydratase-histidinol phosphate phosphatase, a bifunctional enzyme from Salmonella typhimurium.", "content": "Some properties of the catalytic sites of imidazoleglycerol phosphate dehydratase-histidinol phosphate phosphatase, a bifunctional enzyme from Salmonella typhimurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349042"}
{"pmid": "4349043", "title": "Collagenase and hyaluronidase stimulation by dibutyryl adenosine cyclic 3':5'-monophosphate.", "content": "Collagenase and hyaluronidase stimulation by dibutyryl adenosine cyclic 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349043"}
{"pmid": "4349045", "title": "Urinary excretion of cyclic-3',5'-adenosine monophosphate in hyperthyroidism.", "content": "Urinary excretion of cyclic-3',5'-adenosine monophosphate in hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349045"}
{"pmid": "4349044", "title": "Biochemical observations in functioning human thyroid adenomas.", "content": "Biochemical observations in functioning human thyroid adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349044"}
{"pmid": "4349046", "title": "New in vitro tests to detect the thyroid stimulator in sera from hyperthyroid patients by measuring colloid droplet formation and cyclic AMP in human thyroid slices.", "content": "New in vitro tests to detect the thyroid stimulator in sera from hyperthyroid patients by measuring colloid droplet formation and cyclic AMP in human thyroid slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349046"}
{"pmid": "4349048", "title": "A comparison of the  -melanocyte-stimulating hormone and corticotropin response to hypoglycemia.", "content": "A comparison of the  -melanocyte-stimulating hormone and corticotropin response to hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349048"}
{"pmid": "4349047", "title": "Male pseudohermaphroditism due to testicular 17 -hydroxysteroid dehydrogenase deficiency.", "content": "Male pseudohermaphroditism due to testicular 17 -hydroxysteroid dehydrogenase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349047"}
{"pmid": "4349049", "title": "Plasma cortisone concentration as measured by radioimmunoassay.", "content": "Plasma cortisone concentration as measured by radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349049"}
{"pmid": "4349050", "title": "Syndrome of hyporeninemic hypoaldosteronism and hyperkalemia in renal disease.", "content": "Syndrome of hyporeninemic hypoaldosteronism and hyperkalemia in renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349050"}
{"pmid": "4349051", "title": "Proinsulin and insulin release with a human insulinoma and adjacent nonadenomatous pancreas.", "content": "Proinsulin and insulin release with a human insulinoma and adjacent nonadenomatous pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349051"}
{"pmid": "4349053", "title": "Biosynthesis of lymph and plasma lipoprotein apoproteins by isolated perfused rat liver and intestine.", "content": "Biosynthesis of lymph and plasma lipoprotein apoproteins by isolated perfused rat liver and intestine. The ability of rat intestine and liver to synthesize the various apoproteins of plasma lipoproteins was investigated. After the individual isolated organs were perfused with blood containing [(3)H]lysine, chylomicrons plus very low density lipoproteins (VLDL), low density lipoproteins (LDL), and high density lipoproteins (HDL) were isolated from the perfusates and the intestinal lymph. After lipoprotein delipidation, apoproteins were separated by polyacrylamide gel electrophoresis and the (3)H content was determined. Livers incorporated [(3)H]lysine into all apoprotein bands of VLDL and HDL. The (3)H content was greater in large proteins that remained in the stacking gel (group I, predominantly beta-apoprotein) than in proteins with apparent molecular weights near 50,000 (group II) or in the smaller peptides (molecular weights near 10,000, group III). In the intestine, (3)H was incorporated into group I and, in larger amounts, into group II apoproteins of lymph VLDL. No labeled VLDL appeared in the perfusate. (3)H was also incorporated into group II apoproteins of lymph and perfusate HDL. Significantly, no [(3)H]lysine was found in the group III peptides of any lymph or intestinal perfusate lipoproteins. Since these peptides were always present in VLDL from mesenteric lymph collected in vivo, the results suggest that nascent VLDL of gut origin acquires group III peptides from other lipoproteins that penetrate lymph from plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349053"}
{"pmid": "4349052", "title": "Alterations in lipid composition of plasma lipoproteins during deposition of egg yolk.", "content": "Alterations in lipid composition of plasma lipoproteins during deposition of egg yolk. The profiles of total lipids and of the molecular species of individual lipid classes were compared among corresponding lipoproteins of plasma and yolk of the laying hen. A close qualitative correspondence was found in the makeup of the molecular species of glycerophospholipids and triglycerides of the very low density lipoproteins and the high density lipoproteins of plasma and yolk. There was a lower proportion of the trienoic triglycerides and of the dienoic glycerophospholipids in the egg yolk than in the plasma lipoproteins, and the greatest differences (20-30%) were noted between the high density lipoproteins. It was also observed that the plasma high density lipoproteins lost their cholesteryl esters upon entering the yolk. On the basis of these and comparable analyses of the plasma lipoproteins of the nonlaying hen, it is concluded that the laying hen synthesizes specific lipoproteins for deposition in the yolk, and these are carried in plasma and selectively transferred to the developing ovum without significant equilibration with the other plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349052"}
{"pmid": "4349054", "title": "Lipolysis and reesterification: effects of some inhibitors of adenosine 3',5'-cyclic monophosphate phosphodiesterase.", "content": "Lipolysis and reesterification: effects of some inhibitors of adenosine 3',5'-cyclic monophosphate phosphodiesterase. Theophylline and three lipolytic agents, 2,5-bis(2-chloroethylsulfonyl)-pyrrole-3,4-dicarbonitrile (substituted pyrrole), 2,4-diamino-6-butoxy-s-triazine (substituted triazine), and 2,3-dihydro-5,6-dimethyl-3-oxo-4-pyridazinecarbonitrile (substituted pyridazine), stimulate basal lipolysis in adipose tissue in vitro. They also cause an increased release of free fatty acids, but not glycerol, from adipose tissue in which lipolysis is already maximally stimulated by epinephrine. The four compounds also inhibit cyclic AMP phosphodiesterase and the conversion of [1-(14)C]glucose to (14)CO(2). Evidence is presented that free fatty acids accumulate as the result of inhibited reesterification. The substituted pyridazine and triazine, but not the pyrrole, elevate plasma free fatty acids after oral or intraperitoneal administration in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349054"}
{"pmid": "4349055", "title": "Phospholipid metabolism in light and dark adapted excised retina.", "content": "Phospholipid metabolism in light and dark adapted excised retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349055"}
{"pmid": "4349056", "title": "Evidence for involvement of Ca 2+  in the incorporation of  32 P i  into the phosphatidylinositol of rat diaphragm.", "content": "Evidence for involvement of Ca 2+  in the incorporation of  32 P i  into the phosphatidylinositol of rat diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349056"}
{"pmid": "4349057", "title": "Action of neuraminidase (EC 3.2.1.18) from Clostridium perfringens on brain gangliosides in the presence of bile salts.", "content": "Action of neuraminidase (EC 3.2.1.18) from Clostridium perfringens on brain gangliosides in the presence of bile salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349057"}
{"pmid": "4349058", "title": "Analysis of background firing of single sympathetic preganglionic neurons of cat cervical nerve.", "content": "Analysis of background firing of single sympathetic preganglionic neurons of cat cervical nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349058"}
{"pmid": "4349059", "title": "A comparison of electrical properties of neurons in Necturus retina.", "content": "A comparison of electrical properties of neurons in Necturus retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349059"}
{"pmid": "4349060", "title": "Computer-aided statistical analysis of the scintillation camera 131I-hippuran renogram.", "content": "Computer-aided statistical analysis of the scintillation camera 131I-hippuran renogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349060"}
{"pmid": "4349061", "title": "Hypoglycemia in infancy and childhood. II.", "content": "Hypoglycemia in infancy and childhood. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349061"}
{"pmid": "4349063", "title": "Metabolic and biochemical studies in fructose 1,6-diphosphatase deficiency.", "content": "Metabolic and biochemical studies in fructose 1,6-diphosphatase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349063"}
{"pmid": "4349062", "title": "The association of viral and bacterial respiratory infections with exacerbations of wheezing in young asthmatic children.", "content": "The association of viral and bacterial respiratory infections with exacerbations of wheezing in young asthmatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349062"}
{"pmid": "4349066", "title": "Ultrastructural changes in adrenal, spleen and liver tissue, induced by chlorphentermine.", "content": "Ultrastructural changes in adrenal, spleen and liver tissue, induced by chlorphentermine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349066"}
{"pmid": "4349067", "title": "Scoliosis treatment. Skeletal maturity evaluation.", "content": "Scoliosis treatment. Skeletal maturity evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349067"}
{"pmid": "4349081", "title": "Carcinomas of the anorectal region of extramucosal origin with special reference to the anal ducts.", "content": "Carcinomas of the anorectal region of extramucosal origin with special reference to the anal ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349081"}
{"pmid": "4349075", "title": "Immunological aspects of silicosis: possible implications.", "content": "Immunological aspects of silicosis: possible implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349075"}
{"pmid": "4349082", "title": "Angiosarcoma following radical mastectomy. Report on two cases.", "content": "Angiosarcoma following radical mastectomy. Report on two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349082"}
{"pmid": "4349083", "title": "Mechanisms of central transmission of respiratory reflexes.", "content": "Mechanisms of central transmission of respiratory reflexes. Several types of respiratory reflex actions can be discerned according to the reactions of typical respiratory neurons in the efferent part of the central rhythmogenic structure. Whereas respiration runs closely parallel with inspiratory neuron activity the behaviour of expiratory neurons cannot be derived from the resulting reflex changes of respiration. So expiratory apnoea can be combined with continuous activity or with inactivation of expiratory neurons. Extracellular records from a closed uniformly reacting population of expiratory neurons and from neighbouring reticular neurons allowed experimental differentiation between different types of central respiratory reflex actions. In experiments on anaesthetized dogs the responses to chemoreceptor and baroreceptor excitation and to pulmonary inflation were investigated. Chemoreceptor excitation leads to activation of inspiratory, expiratory, and reticular neurons, whereas the baroreceptor afferents act in the opposite direction. In contrast moderate lung inflation causes more specific effects: activation of expiratory neurons, inactivation of inspiratory neurons. But if a certain degree of lung inflations is exceeded a more general inhibition of both inspiratory and expiratory neurons takes place. These results only apply to the \"typical\" respiratory neurons. The principles used to distinguish between the different types of reflexes are proposed for a basis of classification also of other neural, chemical or pharmacological influences on breathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349083"}
{"pmid": "4349084", "title": "The significance of cytoplasmic inclusions in late infantile and juvenile amaurotic idiocy. An ultrastructural study.", "content": "The significance of cytoplasmic inclusions in late infantile and juvenile amaurotic idiocy. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349084"}
{"pmid": "4349085", "title": "Granular cell myoblastoma of stomach.", "content": "Granular cell myoblastoma of stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349085"}
{"pmid": "4349105", "title": "The seroepidemiology of amebiasis.", "content": "The seroepidemiology of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349105"}
{"pmid": "4349107", "title": "Trial of gaviscon in the treatment of gastro-oesophageal reflux of infancy.", "content": "Trial of gaviscon in the treatment of gastro-oesophageal reflux of infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349107"}
{"pmid": "4349106", "title": "Hyperlipoproteinaemia in childhood.", "content": "Hyperlipoproteinaemia in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349106"}
{"pmid": "4349109", "title": "Bases methylated in vitro by cell-free extracts of adenovirus-18-induced tumours.", "content": "Bases methylated in vitro by cell-free extracts of adenovirus-18-induced tumours. The tRNA methylase activity in vitro of adenovirus-18-induced tumour was studied. The activity expressed per mg of protein was the same for extracts of tumours induced by either adenovirus-12 or adenovirus-18. The methylated bases isolated after incubation with extract from adenovirus-18-induced tumour were N(1)-methylguanine, 1-methyladenine, 3-methyladenine and N(6)-methyladenine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349109"}
{"pmid": "4349108", "title": "Proton translocation by rat liver mitochondria with quinones as terminal acceptors.", "content": "Proton translocation by rat liver mitochondria with quinones as terminal acceptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349108"}
{"pmid": "4349110", "title": "Differences in the patterns of methylation in rat liver ribosomal ribonucleic acid after reaction in vivo with methyl methanesulphonate and NN-dimethylnitrosamine.", "content": "Differences in the patterns of methylation in rat liver ribosomal ribonucleic acid after reaction in vivo with methyl methanesulphonate and NN-dimethylnitrosamine. 1. rRNA was isolated from rat liver at short intervals after the intraperitoneal injection of [(14)C]methyl methanesulphonate (50mg/kg) or NN-di[(14)C]methylnitrosamine (2mg/kg). These doses were chosen to minimize the effects of toxicity. 2. The following methods of hydrolysis of [(14)C]methylated rRNA were employed: enzymic digestion to nucleosides at pH8; alkaline hydrolysis and conversion into nucleosides; acid hydrolysis to bases. 3. The methylation products were analysed by chromatography on columns of Dowex-50 (H(+) form) and Dowex-50 (NH(4) (+) form). 4. With both methylating agents the principal product of methylation was 7-methylguanine. Differences were obtained, however, in the molar proportions of the minor bases 3-methylcytosine, 1-methyladenine and 7-methyladenine. Methylation at the O-6 position of guanine was a significant feature of rRNA obtained from the NN-di[(14)C]methylnitrosamine-treated animals but was not detected in rRNA after treatment with [(14)C]methyl methanesulphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349110"}
{"pmid": "4349111", "title": "The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Preparation and properties of islet-cell protein phosphokinase.", "content": "The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Preparation and properties of islet-cell protein phosphokinase. 1. A protein was demonstrated in mammalian islets of Langerhans that after purification appeared as a single component possessing both cyclic-AMP (adenosine 3':5'-cyclic monophosphate)-binding and cyclic-AMP-dependent protein phosphokinase activities. 2. The protein had an intrinsic association constant for cyclic AMP of 1.15x10(-8)m, which was similar to the K(m) for cyclic AMP (1.11x10(-8)m) of the protein phosphokinase activity. 3. Incubation of the protein in the presence of cyclic AMP resulted in its dissociation into cyclic-AMP-independent protein phosphokinase (catalytic) and cyclic-AMP-binding (receptor) subunits, which could be separated on Sephadex G-200. 4. The cyclic-AMP-dependent protein phosphokinase was capable of phosphorylating a variety of proteins, the most readily phosphorylated being histone, casein and protein components of sub-cellular fractions prepared from islets of Langerhans. 5. The cyclic-AMP-dependent phosphorylation of histone had a K(m) for ATP of 1.1x10(-5)m. 6. The endogenous protein phosphokinase activity in rat islets incubated with agents that are known to alter the intracellular concentration of cyclic AMP was investigated. Theophylline and 3-isobutyl-1-methylxanthine, agents that raise cyclic AMP concentrations in islets, increased the activity of the protein phosphokinase, whereas adrenaline, which lowers islet cyclic AMP concentrations, decreased its activity. 7. It is suggested that cyclic AMP may exert its effects on insulin release by increasing the activity of a protein phosphokinase and may thereby promote the phosphorylation and activity of a rate-determining component of the secretory mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349111"}
{"pmid": "4349112", "title": "The primary structure of cytochrome c from the rust fungus Ustilago sphaerogena.", "content": "The primary structure of cytochrome c from the rust fungus Ustilago sphaerogena. 1. The complete amino acid sequence of cytochrome c from the basidiomycete Ustilago sphaerogena was determined from the amino acid compositions and sequences of either tryptic or chymotryptic peptides, and in homology with at least thirty other established sequences of cytochrome c. 2. The primary structure of the molecule bears all of the characteristics of a mammalian-type cytochrome c, showing the typical clustered distribution of hydrophobic and basic residues with a single polypeptide chain of 107 residues. 3. Like all other fungal cytochromes c, it possesses a free N-terminus, and one less residue at the C-terminus than vertebrate cytochromes c. The region of residues 70-80 is strictly conserved, as is histidine at position 18. Position 26 is occupied by an asparagine residue, in contrast to histidine which occurs at this location in most of the known sequences of mammalian-type cytochromes c. 4. In contrast to some other fungal and plant cytochromes c of known primary structures, the Ustilago cytochrome c molecule does not contain trimethyl-lysine. 5. The sequence of Ustilago cytochrome c differs from the sequences of human, horse, chicken, tuna, wheat, and baker's yeast proteins at loci 47, 43, 44, 44 and 38 respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349112"}
{"pmid": "4349113", "title": "The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872.", "content": "The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872. 1. Pseudomonas N.C.I.B. 9872 grown on cyclopentanol as carbon source oxidized it at a rate of 228mul of O(2)/h per mg dry wt. and the overall consumption of 5.9mumol of O(2)/mumol of substrate. Cyclopentanone was oxidized at a similar rate with the overall consumption of 5.2mumol of O(2)mumol of substrate. Cells grown with sodium acetate as sole source of carbon were incapable of significant immediate oxidation of these two substrates. 2. Disrupted cells catalysed the oxidation of cyclopentanol to cyclopentanone by the action of an NAD(+)-linked dehydrogenase with an alkaline pH optimum. 3. A cyclopentanolinduced cyclopentanone oxygenase (specific activity 0.11mumol of NADPH oxidized/min per mg of protein) catalysed the consumption of 1mumol of NADPH and 0.9mumol of O(2) in the presence of 1mumol of cyclopentanone. NADPH oxidation did not occur under anaerobic conditions. The only detectable reaction product with 100000g supernatant was 5-hydroxyvalerate. 4. Extracts of cyclopentanol-grown cells contained a lactone hydrolase (specific activity 7.0mumol hydrolysed/min per mg of protein) that converted 5-valerolactone into 5-hydroxyvalerate. 5. Cyclopentanone oxygenase fractions obtained from a DEAE-cellulose column were almost devoid of 5-valerolactone hydrolase and catalysed the formation of 5-valerolactone in high yield from cyclopentanone in the presence of NADPH. 6. Incubation of 5-hydroxyvalerate with the 100000g supernatant, NAD(+) and NADP(+) under aerobic conditions resulted in the consumption of O(2) and the conversion of 5-hydroxyvalerate into glutarate. 7. The high activity of isocitrate lyase in cyclopentanol-grown cells suggests that the further oxidation of glutarate proceeds through as yet uncharacterized reactions to acetyl-CoA. 8. The reaction sequence for the oxidation of cyclopentanol by Pseudomonas N.C.I.B. 9872 is: cyclopentanol --> cyclopentanone --> 5-valerolactone --> 5-hydroxyvalerate --> glutarate --> --> acetyl-CoA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349113"}
{"pmid": "4349114", "title": "The acid and enzymic hydrolysis of O-acetylated sialic acid residues from rabbit Tamm-Horsfall glycoprotein.", "content": "The acid and enzymic hydrolysis of O-acetylated sialic acid residues from rabbit Tamm-Horsfall glycoprotein. Rabbit Tamm-Horsfall glycoprotein and bovine submaxillary glycoprotein were both found to contain sialic acid residues which are released at a slow rate by the standard conditions of acid hydrolysis. These residues are also resistant to neuraminidases from Vibrio cholerae and Clostridium perfringens. This behaviour was attributed to the presence of O-acetylated sialic acid, since the removal of O-acetyl groups by mild alkaline treatment normalized the subsequent release of sialic acid from rabbit Tamm-Horsfall glycoprotein by acid and by enzymic hydrolysis. Determination of the O-acetyl residues in rabbit Tamm-Horsfall glycoprotein indicated that on average two hydroxyl groups of sialic acid are O-acetylated, and these were located on the polyhydroxy side-chain of sialic acid or on C-4 and C-8. These findings confirm the assumption that certain O-acetylated forms of sialic acid are not substrates for bacterial neuraminidases. Several explanations have been suggested to explain the effect of O-acetylation of the side-chain on the rate of acidcatalysed hydrolysis of sialic acid residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349114"}
{"pmid": "4349115", "title": "Complete amino acid analysis of peptides and proteins after hydrolysis by a mixture of sepharose-bound peptidases.", "content": "Complete amino acid analysis of peptides and proteins after hydrolysis by a mixture of sepharose-bound peptidases. Incubation with a mixture of Sepharose-bound peptidases was shown to result in the quantitative release of amino acids from certain peptides and S-aminoethylated proteins. Subtraction of the low background values of amino acids generated by the enzymes enables amino acid ratios of corticotrophin-(1-24)-tetracosapeptide to be determined with a standard deviation on repeat digestions of 3-5%. Good values were obtained for amino acids that are completely or partially destroyed on acid hydrolysis, i.e. tryptophan, tyrosine, serine, asparagine and glutamine. Experiments with peptides containing d-amino acids showed that the enzyme mixture is stereospecific and could therefore be used to detect the presence of d-residues in peptides. The enzyme mixture completely hydrolyses peptide fragments obtained after Edman degradation and should therefore be useful for determining sequences of peptides containing acid-labile amino acid residues. The activities of the bound enzymes were unaltered over a period of 7 months and they provide a simple, reproducible procedure for the quantitative determination of amino acids in peptides and proteins containing l-amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349115"}
{"pmid": "4349116", "title": "A study of the phosphate linkages in phosphomannan in cell walls of Saccharomyces cerevisiae.", "content": "A study of the phosphate linkages in phosphomannan in cell walls of Saccharomyces cerevisiae. 1. The phosphomannan of Saccharomyces cerevisiae was released by Pronase digestion of cell walls and isolated by chromatography on DEAE-cellulose or by precipitation with borate-Cetavlon solutions. Mannose and phosphorus were present in the molar ratio 18:1 and the phosphate groups were in the diester form. 2. Hydrolysis with acid gave mannose 6-phosphate. Under mild acid conditions (autohydrolysis) the phosphate groups were converted into the monoester form, mannose was released and the molecular size of the phosphomannan was substantially decreased. 3. Hydrolysis with alkali also gave a monoester phosphate and a similar decrease in molecular weight. Under mild alkaline conditions the serine and threonine content of the phosphomannan was decreased by about 80%. The phosphate content was not altered. 4. Treatment with 40% (v/v) HF removed 70% of the phosphorus from the phosphomannan with no detectable decrease in molecular weight. 5. Periodate oxidation gave an oxophosphomannan from which 80% of the phosphorus was eliminated under mild alkaline conditions. 6. The properties of the phosphomannan are consistent with a structure in which the phosphate groups are located on the outside of the molecule and link C-1 of a terminal mannose unit with C-6 of another mannose unit, which is in turn attached to the polysaccharide backbone of the molecule. 7. The implications of this structure are discussed in relation to flocculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349116"}
{"pmid": "4349118", "title": "The oxidation of nicotinic acid by Pseudomonas ovalis Chester. The terminal oxidase.", "content": "The oxidation of nicotinic acid by Pseudomonas ovalis Chester. The terminal oxidase. In cell-free extracts of Pseudomonas ovalis nicotinic acid oxidase is confined to the wallmembrane fraction. It is associated with an electron-transport chain comprising b- and c-type cytochromes only, differing proportions of which are reduced by nicotinate and NADH. CO difference-spectra show two CO-binding pigments, cytochrome o (absorption maximum at 417nm) and another component absorbing maximally at 425nm. Cytochrome o is not reduced by NADH or by succinate but is by nicotinate, which can also reduce the ;425' CO-binding pigment. The effects of inhibitors of terminal oxidation support the idea of two terminal oxidases and a scheme involving the ;425' CO-binding pigment and the other components of the electron-transport chain is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349118"}
{"pmid": "4349117", "title": "The binding of ribosomal subunits to endoplasmic reticulum membranes.", "content": "The binding of ribosomal subunits to endoplasmic reticulum membranes. The binding of ribosomes and ribosomal subunits to endoplasmic reticulum preparations of mouse liver was studied. (1) Membranes prepared from rough endoplasmic reticulum by preincubation with 0.5m-KCl and puromycin bound 60-80% of added 60S subunits and 10-15% of added 40S subunits. Membranes prepared with pyrophosphate and citrate showed less clear specificity for 60S subunits particularly when assayed at low ionic strengths. (2) Ribosomal 40S subunits bound efficiently to membranes only in the presence of 60S subunits. The reconstituted membrane-60S subunit-40S subunit complex was active in synthesis of peptide bonds. (3) No differences in binding to membranes were seen between subunits derived from free and from membrane-bound ribosomes. (4) It is concluded that the binding of ribosomes to membranes does not require that they be translating a messenger RNA, and that the mechanism whereby bound and free ribosomes synthesize different groups of proteins does not depend on two groups of ribosomes that differ in their ability to bind to endoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349117"}
{"pmid": "4349119", "title": "A comparative study of the molecular structures of the plasma membranes and the smooth and the rough endoplasmic-reticulum membranes from rat liver.", "content": "A comparative study of the molecular structures of the plasma membranes and the smooth and the rough endoplasmic-reticulum membranes from rat liver. Plasma-membrane as well as smooth-, rough- and degranulated-endoplasmic-reticulum-membrane fractions were isolated from the microsomal pellet of rat liver. The purity of these fractions, as determined by marker-enzyme activities, electron microscopy, cholesterol content and RNA content, was found to be adequate for a comparative structural study. Major differences in lipid and protein composition were found to exist between the plasma membrane and the endoplasmic reticulum, but not between the smooth and the rough fractions of the endoplasmic reticulum. Differences in the location of membrane protein thiol groups and the mobility of the membrane phospholipids were observed between the plasma membranes and the endoplasmic reticulum, and these could be explained by differences in protein and lipid composition. However, by employing fluorescence and spin-labelling techniques structural changes were also observed between the smooth and the rough endoplasmic-reticulum fractions. These results suggest that the structural heterogeneity existing between the two latter membrane fractions occurs near or on their membrane surfaces and is not due to the greater number of ribosomes bound to the rough endoplasmic-reticulum fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349119"}
{"pmid": "4349124", "title": "Neuronal hyperactivity following deafferentation of the lateral cuneate nucleus.", "content": "Neuronal hyperactivity following deafferentation of the lateral cuneate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349124"}
{"pmid": "4349123", "title": "Effects of cryogenic blocking of pulvinar upon visually evoked responses in the cortex of the cat.", "content": "Effects of cryogenic blocking of pulvinar upon visually evoked responses in the cortex of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349123"}
{"pmid": "4349122", "title": "Actions of glutamic acid on spinal neurones.", "content": "Actions of glutamic acid on spinal neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349122"}
{"pmid": "4349121", "title": "Theophylline compounds and myasthenia gravis. II. Clinical report of nine cases.", "content": "Theophylline compounds and myasthenia gravis. II. Clinical report of nine cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349121"}
{"pmid": "4349129", "title": "Retardation of peripheral nerve myelination in mice treated with inhibitors of cholesterol biosynthesis. A quantitative electron microscopic study.", "content": "Retardation of peripheral nerve myelination in mice treated with inhibitors of cholesterol biosynthesis. A quantitative electron microscopic study. The effect of two inhibitors of cholesterol biosynthesis, triparanol and AY 9944, on peripheral nerve myelination, was studied. Suckling mice were intraperitoneally injected with both drugs on 3 consecutive days and were sacrificed 6 hr after the last injection; others were suckled by an injected mother and sacrificed at 2(1/2) days of age. A single mouse which had been injected with both drugs at 1, 2, and 3 days of age was sacrificed 2 wk after the last injection. Membranous and crystalline intracytoplasmic inclusions were observed in the Schwann cells of the sciatic nerves of all the experimental animals. Both the number of unmyelinated single axons and the number of myelin lamellae around each myelinating axon in the sciatic nerves were recorded for treated mice and of mice suckled by treated mothers. The sciatic nerve of the experimental mice contained a larger proportion of unmyelinated single axons and smaller numbers of myelin lamellae around the myelinating axons, when compared with age-matched controls. The results suggest that a decrease of endogenous cholesterol in suckling mice may affect peripheral nerve myelination in two ways: by retarding the \"triggering\" of myelination in unmyelinated axons and by decreasing the rate of myelination already in progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349129"}
{"pmid": "4349130", "title": "The intrarenal distribution of tritiated para-aminohippuric acid determined by a modified technique of section freeze-dry radioautography.", "content": "The intrarenal distribution of tritiated para-aminohippuric acid determined by a modified technique of section freeze-dry radioautography. Section freeze-dry radioautography has been used to examine the intrarenal distribution of a water-soluble organic acid (para-aminohippuric acid (PAH-3H)) under constant-infusion, steady-state conditions in mouse and rat kidney in vivo. The technique described here has the following advantages: (a) Sectioning and freeze-drying are accomplished in a closed cryostat at temperatures below -40 degrees C; (b) Handling of the section is facilitated by mounting of the section-to-be on adhesive-coated Saran Wrap prior to cutting; (c) Unembedded freeze-dried sections are attached to photographic film at ambient temperature in the dark room; (d) Fixation follows completion of radioautographic exposure and precedes photographic development; (e) Permanent close contact is maintained between tissue and film. Morphologic preservation compared favorably with that obtained by optimal fixation techniques, which, however, permit diffusion. Cellular accumulation of PAH-3H during secretion was demonstrated in the proximal tubule under steady-state conditions in vivo. The cellular concentration of PAH-3H was uniform throughout the length of the proximal tubule in mouse and rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349130"}
{"pmid": "4349131", "title": "Basal body replication and cilogenesis in a suctorian, Tokophrya infusionum.", "content": "Basal body replication and cilogenesis in a suctorian, Tokophrya infusionum. Basal body replication and ciliogenesis in Tokophrya infusionum were studied in synchronized cultures. Basal body replication occurs during the 1st hr of reproduction, which in Tokophrya is by internal budding. The number of basal bodies increases from about 20 to over 300 within this period. New basal bodies develop in association with mature basal bodies; they are formed at right angles to the mature basal body as short \"probasal\" bodies, which elongate, slant upward, become parallel to the mature basal body, and elongate to the mature size. Ciliogenesis occurs only during reproduction; the nonreproducing adult is not ciliated, and has only 18-25 barren basal bodies. Cilia first appear as short bulges above the basal body. The axonemal structure is incomplete at first, with one or both central microtubules absent, and occasionally the B fibers of the outer doublets are missing. Several accessory fibers are associated with the basal bodies, both in the adult and during reproduction. One of the fibers appears only after the cilia have sprouted. The scheme of basal body replication and ciliogenesis in Tokophrya is compared to that reported in other organisms, and the role of the accessory fibers is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349131"}
{"pmid": "4349133", "title": "Nuclear and organelle RNA synthesis in ochromonas: the effects of light.", "content": "Nuclear and organelle RNA synthesis in ochromonas: the effects of light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349133"}
{"pmid": "4349134", "title": "Photooxidation of diaminobenzidine (DAB) by chloroplast lamellae.", "content": "Photooxidation of diaminobenzidine (DAB) by chloroplast lamellae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349134"}
{"pmid": "4349132", "title": "A new method for the preparation of rat liver lysosomes. Separation of cell organelles of rat liver by carrier-free continuous electrophoresis.", "content": "A new method for the preparation of rat liver lysosomes. Separation of cell organelles of rat liver by carrier-free continuous electrophoresis. A combination of differential centrifugation and carrier-free continuous electrophoresis is introduced as a new method for the isolation of animal cell organelles. Various buffers were systematically checked in order to find the system which preserves the organelles and gives as well a good separation in the free-flow electrophoresis apparatus. Triethanolamine-acetate buffer (10 mM), pH 7.4 was used. The isolated lysosomes were pure according to marker enzymes and electron micrographs. A heterogeneity of the lysosomes in electrophoretic mobility was demonstrated with respect to the marker enzymes arylsulfatase and beta-glucuronidase. The lysosomes with higher mobility showed a maximum enrichment of 240-fold with respect to arylsulfatase. The lysosomes with lower electrophoretic mobility showed a 65-fold enrichment with respect to beta-glucuronidase. The ratio of beta-glucuronidase to arylsulfatase varied from 2:1 to 1:2 in lysosomes of different mobility. The yield amounted to approximately 1 mg of lysosomal protein per gram of liver protein. 5-8 mg of lysosomes can be obtained in one experiment. The electrophoretic separation proves to be an effective tool in obtaining pure and well preserved lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349132"}
{"pmid": "4349135", "title": "Patterns of cytomegaloviral complement-fixing antibody activity: a longitudinal study of blood donors.", "content": "Patterns of cytomegaloviral complement-fixing antibody activity: a longitudinal study of blood donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349135"}
{"pmid": "4349137", "title": "Complement as a mediator of inflammation in acute gouty arthritis. I. Studies on the reaction between human serum complement and sodium urate crystals.", "content": "Complement as a mediator of inflammation in acute gouty arthritis. I. Studies on the reaction between human serum complement and sodium urate crystals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349137"}
{"pmid": "4349136", "title": "The relationship between insulin secretion and triglyceride concentration in endogenous lipemia.", "content": "The relationship between insulin secretion and triglyceride concentration in endogenous lipemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349136"}
{"pmid": "4349138", "title": "The use of polyacrylamide gel electrophoresis in differentiating type 3 hyperlipoproteinemia.", "content": "The use of polyacrylamide gel electrophoresis in differentiating type 3 hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349138"}
{"pmid": "4349139", "title": "Some practical innovations in the biological assay of adrenocorticotropic hormone (ACTH).", "content": "Some practical innovations in the biological assay of adrenocorticotropic hormone (ACTH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349139"}
{"pmid": "4349149", "title": "Participation of macrophages in tumor immunity.", "content": "Participation of macrophages in tumor immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349149"}
{"pmid": "4349148", "title": "Relationship between blocking and unblocking activity and tumor growth in vivo.", "content": "Relationship between blocking and unblocking activity and tumor growth in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349148"}
{"pmid": "4349151", "title": "Introduction: diagnosis and immunotherapy of cancer.", "content": "Introduction: diagnosis and immunotherapy of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349151"}
{"pmid": "4349150", "title": "Augmented immunogenicity of tumor cell homogenates produced by infection with influenza virus.", "content": "Augmented immunogenicity of tumor cell homogenates produced by infection with influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349150"}
{"pmid": "4349152", "title": "Histopathology of Mycobacterium bovis (BCG)-mediated tumor regression.", "content": "Histopathology of Mycobacterium bovis (BCG)-mediated tumor regression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349152"}
{"pmid": "4349153", "title": "Alpha-1-fetoprotein: serologic marker of human hepatoma and embryonal carcinoma.", "content": "Alpha-1-fetoprotein: serologic marker of human hepatoma and embryonal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349153"}
{"pmid": "4349154", "title": "In vitro methods for assessment of antibody-mediated tumor immunity.", "content": "In vitro methods for assessment of antibody-mediated tumor immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349154"}
{"pmid": "4349155", "title": "Relationship between catecholamines and ACTH: effects of 6-hydroxy-dopamine.", "content": "Relationship between catecholamines and ACTH: effects of 6-hydroxy-dopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349155"}
{"pmid": "4349156", "title": "Determination of the nucleotide sequence of a fragment of bacteriophage phiX 174 DNA.", "content": "Determination of the nucleotide sequence of a fragment of bacteriophage phiX 174 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349156"}
{"pmid": "4349157", "title": "Influence of adeno-associated satellite virus on adenovirus-induced tumours in hamsters.", "content": "Influence of adeno-associated satellite virus on adenovirus-induced tumours in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349157"}
{"pmid": "4349158", "title": "Supercoiling of SV40 DNA can occur independently of replication.", "content": "Supercoiling of SV40 DNA can occur independently of replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349158"}
{"pmid": "4349159", "title": "Occurrence of aminoacyl-tRNA synthetase in an RNA oncogenic virus.", "content": "Occurrence of aminoacyl-tRNA synthetase in an RNA oncogenic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349159"}
{"pmid": "4349161", "title": "Studies on endoneoplastic transformation of glial tumors in vitro in long-term tissue cultures and subcultures.", "content": "Studies on endoneoplastic transformation of glial tumors in vitro in long-term tissue cultures and subcultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349161"}
{"pmid": "4349164", "title": "Carcinoma of the pancreas.", "content": "Carcinoma of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349164"}
{"pmid": "4349165", "title": "Glomus jugalare tumors: review and report of two cases.", "content": "Glomus jugalare tumors: review and report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349165"}
{"pmid": "4349166", "title": "The clinical laboratory in the investigation of patients with head injury.", "content": "The clinical laboratory in the investigation of patients with head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349166"}
{"pmid": "4349167", "title": "Effects of a week of ACTH or corticosteroid treatment on the diuretic response to water intake. A probably neuropostpituitary response to corticosteroid load.", "content": "Effects of a week of ACTH or corticosteroid treatment on the diuretic response to water intake. A probably neuropostpituitary response to corticosteroid load.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349167"}
{"pmid": "4349169", "title": "On the fine structure of free nerve endings in human digital skin, oral cavity and rectum.", "content": "On the fine structure of free nerve endings in human digital skin, oral cavity and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349169"}
{"pmid": "4349162", "title": "Laboratory evaluation of hypertension: renal mechanisms.", "content": "Laboratory evaluation of hypertension: renal mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349162"}
{"pmid": "4349170", "title": "Lysosomal structures in the stratum corneum of the ruminal epithelium of the sheep.", "content": "Lysosomal structures in the stratum corneum of the ruminal epithelium of the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349170"}
{"pmid": "4349171", "title": "Studies on the trophoblastic nidation of the mouse ovum.", "content": "Studies on the trophoblastic nidation of the mouse ovum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349171"}
{"pmid": "4349172", "title": "Platelets in the cytoplasm of adrenocortical cells injured by temporary ischemia.", "content": "Platelets in the cytoplasm of adrenocortical cells injured by temporary ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349172"}
{"pmid": "4349173", "title": "Hydrosmotic effect of angiotensin II: isolated toad bladder.", "content": "Hydrosmotic effect of angiotensin II: isolated toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349173"}
{"pmid": "4349174", "title": "Effects of ACTH and salt on blood pressure and steroid secretion in rats.", "content": "Effects of ACTH and salt on blood pressure and steroid secretion in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349174"}
{"pmid": "4349175", "title": "Constrictor activity of angiotensins I and II on perfused vascular circuits of the dog.", "content": "Constrictor activity of angiotensins I and II on perfused vascular circuits of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349175"}
{"pmid": "4349176", "title": "Renal gluconeogenesis and mitochondrial NAD+-NADH ratios in nursing and adult rats.", "content": "Renal gluconeogenesis and mitochondrial NAD+-NADH ratios in nursing and adult rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349176"}
{"pmid": "4349177", "title": "Mechanism of action of antiotensin II and antidiuretic hormone on renin secretion.", "content": "Mechanism of action of antiotensin II and antidiuretic hormone on renin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349177"}
{"pmid": "4349179", "title": "Renin-angiotensin system in primitive bony fishes and a holocephalian.", "content": "Renin-angiotensin system in primitive bony fishes and a holocephalian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349179"}
{"pmid": "4349178", "title": "Effects of altitude stress on mitochondrial function.", "content": "Effects of altitude stress on mitochondrial function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349178"}
{"pmid": "4349180", "title": "The roentgenographic manifestations of pulmonary opportunistic infections.", "content": "The roentgenographic manifestations of pulmonary opportunistic infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349180"}
{"pmid": "4349181", "title": "Cavitating pulmonary metastatic disease in children.", "content": "Cavitating pulmonary metastatic disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349181"}
{"pmid": "4349182", "title": "Improved cryostat for spectrophotometry of cytochromes.", "content": "Improved cryostat for spectrophotometry of cytochromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349182"}
{"pmid": "4349183", "title": "Immobilized enzymes: a prototype apparatus for oxidase enzymes in chemical analysis utilizing covalently bound glucose oxidase.", "content": "Immobilized enzymes: a prototype apparatus for oxidase enzymes in chemical analysis utilizing covalently bound glucose oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349183"}
{"pmid": "4349184", "title": "Human leukocyte interferon produced by use of an antibody-free human serum fraction.", "content": "Human leukocyte interferon produced by use of an antibody-free human serum fraction. An antibody-free human serum fraction has been prepared by ammonium sulfate precipitation. This fraction can be substituted for whole serum in the production of optimal yields of interferon by induced human leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349184"}
{"pmid": "4349185", "title": "Production and purification of large amounts of Rous sarcoma virus.", "content": "Production and purification of large amounts of Rous sarcoma virus. Procedures are described for production and purification of large amounts of Rous sarcoma virus. The virus was produced by Rous sarcoma virus-transformed chicken embryo fibroblasts in roller culture which produced up to 6 mg of virus per day per liter of supernatant fluid. Various methods of concentrating virus were evaluated; pelleting yielded the best results in terms of recovery of infectious virus. Purification was achieved by means of successive velocity and equilibrium density centrifugation by using sucrose solutions made in low-salt buffer. A rapid method for the optical density measurement of virus concentration was also developed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349185"}
{"pmid": "4349186", "title": "Procedure for drying leptospiral antibody on sand and sugar for serological studies in leptospirosis.", "content": "Procedure for drying leptospiral antibody on sand and sugar for serological studies in leptospirosis. A simple technique is described for drying sera on washed, dry sand or ordinary sugar cubes for the sero-diagnosis of leptospirosis. The results are shown to be very similar to those obtained with fluid sera or sera dried on filter paper discs. Sera adsorbed on sand or absorbed in sugar eliminated some of the problems associated with sera dried on paper. This method is suitable for use in the field and is expected to be of value in epizootiological studies where contamination and chemical denaturation of fluid serum samples held without refrigeration is a problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349186"}
{"pmid": "4349187", "title": "Method for detecting mycoplasma and bacterial L-form colonies in relief with an ordinary light microscope by means of oblique light.", "content": "Method for detecting mycoplasma and bacterial L-form colonies in relief with an ordinary light microscope by means of oblique light. A simple method is described for obtaining images in relief of fresh preparations with an ordinary light microscope by lowering the condenser and displacing the objective at an \"off-clicked\" position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349187"}
{"pmid": "4349190", "title": "Sleep-wakefulness, EEG and behavioral studies of chronic cats without neocortex and striatum: the 'diencephalic' cat.", "content": "Sleep-wakefulness, EEG and behavioral studies of chronic cats without neocortex and striatum: the 'diencephalic' cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349190"}
{"pmid": "4349191", "title": "Sleep-wakefulness, EEG and behavioral studies of chronic cats without the thalamus: the 'athalamic' cat.", "content": "Sleep-wakefulness, EEG and behavioral studies of chronic cats without the thalamus: the 'athalamic' cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349191"}
{"pmid": "4349210", "title": "A theoretical model of the cerebral cortex.", "content": "A theoretical model of the cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349210"}
{"pmid": "4349211", "title": "The interdependence series matrix; a method for determining the serial dependence of neuronal interspike intervals.", "content": "The interdependence series matrix; a method for determining the serial dependence of neuronal interspike intervals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349211"}
{"pmid": "4349212", "title": "On the transduction of visual, mechanical, and chemical stimuli.", "content": "On the transduction of visual, mechanical, and chemical stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349212"}
{"pmid": "4349213", "title": "Action of ATP on the neural tissue-limb deplant of the salamander.", "content": "Action of ATP on the neural tissue-limb deplant of the salamander.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349213"}
{"pmid": "4349214", "title": "Activity of enzymes related to neurotransmission in neuronal and glial fractions.", "content": "Activity of enzymes related to neurotransmission in neuronal and glial fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349214"}
{"pmid": "4349215", "title": "Radiation damage to proteins--an e.s.r. study of a single crystal of glycyl-glycine at low temperatures.", "content": "Radiation damage to proteins--an e.s.r. study of a single crystal of glycyl-glycine at low temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349215"}
{"pmid": "4349216", "title": "Formation and trapping of radical pairs in irradiated thymine.", "content": "Formation and trapping of radical pairs in irradiated thymine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349216"}
{"pmid": "4349217", "title": "E.p.r. of free radicals formed in DNA and its constituents after exposure to discharge-excited inert gases. I. Thymine and thymidine.", "content": "E.p.r. of free radicals formed in DNA and its constituents after exposure to discharge-excited inert gases. I. Thymine and thymidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349217"}
{"pmid": "4349219", "title": "Diagnosis of upper and mid inferior vena caval obstruction.", "content": "Diagnosis of upper and mid inferior vena caval obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349219"}
{"pmid": "4349222", "title": "Two actions of cyclic AMP on melanosome movement in frog skin. Dissection by cytochalasin B.", "content": "Two actions of cyclic AMP on melanosome movement in frog skin. Dissection by cytochalasin B. Photomicrography and reflectance microphotometry were used to monitor melanosome movement in frog skin melanocytes in vitro in response to hormonal stimulation and cytochalasin B (CB). Melanocyte-stimulating hormone (MSH), theophylline, and dibutyryl cyclic AMP (DiBcAMP) induced melanosome dispersion (darkening) which was promptly arrested by cytochalasin B in concentrations of 5-20 microg/ml. Melanosome aggregation (skin lightening) occurred only after removal of the darkening agent (MSH, theophylline, or DiBcAMP) and proceeded in the presence or absence of CB. When CB was added to darkened skins, they did not lighten and melanosomes remained in the dispersed state. Use of CB has permitted the dissection of cyclic AMP-mediated melanosome dispersion into two distinct events. The first, induction of melanosome dispersion, is CB sensitive. The second action of intracellular cyclic AMP involves an uncoupling of the centripetal motive force, and is CB insensitive. In the latter process, production of cyclic AMP appears to produce the same result as application of microtubule-disrupting agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349222"}
{"pmid": "4349220", "title": "Ultrastructural localization of phospholipid synthesis in the rat trigeminal nerve during myelination.", "content": "Ultrastructural localization of phospholipid synthesis in the rat trigeminal nerve during myelination. A method for the ultrastructural localization of acyltransferase enzymes involved in phospholipid metabolism has been applied to the developing rat trigeminal nerve. Determination of acyltransferase levels in the nerve indicated that a peak of activity occurs at the 8th day after birth with gradual declines of activity up to 15 days. Morphological surveys and determinations of cholesterol levels suggested that heavy myelin formation occurs in the nerve during this latter period. Fixed nerves incubated in a medium for localization of acyltransferases indicated deposition of reaction product associated with Golgi cisternae, intracellular smooth vesicles, and the plasma membrane of the Schwann cell in the incipient stages of myelin formation. Golgi-derived vesicles appeared to move toward the Schwann cell surface and fuse with the plasma membrane. Activity continued to be detectable in the plasma membrane of the internal mesaxon as long as cytoplasm was evident and mature myelin membrane was not yet formed. Cells in which myelin formation appeared advanced showed little or no enzyme marker. Consistent with cytochemical observations were biochemical determinations of acyltransferases which showed high levels of the enzymes in microsomes, while no activity could be detected in the myelin fraction. Acyltransferase reaction product was also observed in the Golgi apparatus of ganglion cell bodies, axoplasmic smooth vesicles, and the axolemma. Localization of acyltransferase enzymes in Schwann cells, ganglion cell bodies, and axons during development of the nerve is discussed in relation to membrane biogenesis in the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349220"}
{"pmid": "4349221", "title": "Localization of Na + , K + -ATPase and other enzymes in teleost pseudobranch. I. Biochemical characterization of subcellular fractions.", "content": "Localization of Na + , K + -ATPase and other enzymes in teleost pseudobranch. I. Biochemical characterization of subcellular fractions. In an effort to determine the subcellular localization of sodium- and potassium-activated adenosine triphosphatase (Na(+), K(+)-ATPase) in the pseudobranch of the pinfish Lagodon rhomboides, this tissue was fractionated by differential centrifugation and the activities of several marker enzymes in the fractions were measured. Cytochrome c oxidase was found primarily in the mitochondrial-light mitochondrial (M+L) fraction. Phosphoglucomutase appeared almost exclusively in the soluble (S) fraction. Monoamine oxidase was concentrated in the nuclear (N) fraction, with a significant amount also in the microsomal (P) fraction but little in M+L or S. Na(+), K(+)-ATPase and ouabain insensitive Mg(2+)-ATPase were distributed in N, M+L, and P, the former having its highest specific activity in P and the latter in M+L. Rate sedimentation analysis of the M+L fraction indicated that cytochrome c oxidase and Mg(2+)-ATPase were associated with a rapidly sedimenting particle population (presumably mitochondria), while Na(+), K(+)-ATPase was found primarily in a slowly sedimenting component. At least 75% of the Na(+), K(+)-ATPase in M+L appeared to be associated with structures containing no Mg(2+)-ATPase. Kinetic properties of the two ATPases were studied in the P fraction and were typical of these enzymes in other tissues. Na(+), K(+)-ATPase activity was highly dependent on the ratio of Na(+) and K(+) concentrations but independent of absolute concentrations over at least a fourfold range.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349221"}
{"pmid": "4349223", "title": "Retinal structure in the smooth dogfish, Mustelus canis: light microscopy of photoreceptor and horizontal cells.", "content": "Retinal structure in the smooth dogfish, Mustelus canis: light microscopy of photoreceptor and horizontal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349223"}
{"pmid": "4349225", "title": "Chemotherapy of cutaneous herpesvirus infection of hairless mice.", "content": "Chemotherapy of cutaneous herpesvirus infection of hairless mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349225"}
{"pmid": "4349224", "title": "The responses of the sebaceous glands of the hypophysectomized-castrated male rat to 5 -androstanedione and 5 -androstane-3 ,17 -diol.", "content": "The responses of the sebaceous glands of the hypophysectomized-castrated male rat to 5 -androstanedione and 5 -androstane-3 ,17 -diol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349224"}
{"pmid": "4349227", "title": "Detection of heterozygous carriers of the Lesch-Nyhan syndrome by electrophoresis of hair root lysates.", "content": "Detection of heterozygous carriers of the Lesch-Nyhan syndrome by electrophoresis of hair root lysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349227"}
{"pmid": "4349226", "title": "Congenital adrenal hypoplasia: an isolated defect of organogenesis.", "content": "Congenital adrenal hypoplasia: an isolated defect of organogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349226"}
{"pmid": "4349228", "title": "A Y-autosome translocation 46,X,t(Yq-7q+) associated with multiple congenital anomalies.", "content": "A Y-autosome translocation 46,X,t(Yq-7q+) associated with multiple congenital anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349228"}
{"pmid": "4349229", "title": "Antidiuretic therapy in Bartter's syndrome.", "content": "Antidiuretic therapy in Bartter's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349229"}
{"pmid": "4349231", "title": "Tracheostomy in primary herpetic gingivostomatitis.", "content": "Tracheostomy in primary herpetic gingivostomatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349231"}
{"pmid": "4349230", "title": "Familial glucocorticoid insufficiency.", "content": "Familial glucocorticoid insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349230"}
{"pmid": "4349232", "title": "Poland's syndrome associated with leukemia.", "content": "Poland's syndrome associated with leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349232"}
{"pmid": "4349236", "title": "Vascular permeability factor: dissociation from the angiotensin II induced pressor and drinking responses.", "content": "Vascular permeability factor: dissociation from the angiotensin II induced pressor and drinking responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349236"}
{"pmid": "4349235", "title": "Reactions between an insect picornavirus and naturally occurring IgM antibodies in several mammalian species.", "content": "Reactions between an insect picornavirus and naturally occurring IgM antibodies in several mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349235"}
{"pmid": "4349237", "title": "Cyclic AMP does not affect the rate at which cells attach to a substratum.", "content": "Cyclic AMP does not affect the rate at which cells attach to a substratum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349237"}
{"pmid": "4349238", "title": "Comparison of the redox assay for ACTH with previous assays.", "content": "Comparison of the redox assay for ACTH with previous assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349238"}
{"pmid": "4349239", "title": "Nitrofurantoin polyneuropathy.", "content": "Nitrofurantoin polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349239"}
{"pmid": "4349242", "title": "The effect of ACTH administration on plasma testosterone, dihydrotestosterone and serum LH concentrations in normal men.", "content": "The effect of ACTH administration on plasma testosterone, dihydrotestosterone and serum LH concentrations in normal men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349242"}
{"pmid": "4349246", "title": "Regulation of staphylococcal enterotoxin B: effect of anaerobic shock.", "content": "Regulation of staphylococcal enterotoxin B: effect of anaerobic shock. The metabolism of glucose during enterotoxin B synthesis in Staphylococcus aureus S-6 was examined under anaerobic conditions in the presence and absence of nitrate. The repression of enterotoxin synthesis which occurs during the oxidative metabolism of glucose was relieved after a shift to anaerobic conditions; glucose was then converted primarily to lactic acid and was metabolized more rapidly, presumably to obtain the equivalent amount of energy available aerobically. A greater proportion of oxidized end products and evidently more energy per glucose molecule was produced in the presence of oxygen. Thus, available energy as judged by a change in the type and proportion of end products appears to be related to the degree of toxin repression. As expected, the addition of nitrate during anaerobic glucose metabolism prevented derepression of toxin synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349246"}
{"pmid": "4349240", "title": "On the state of the nervous system.", "content": "On the state of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349240"}
{"pmid": "4349247", "title": "Comparison of direct and indirect solid-phase microradioimmunoassays for the detection of viral antigens and antiviral antibody.", "content": "Comparison of direct and indirect solid-phase microradioimmunoassays for the detection of viral antigens and antiviral antibody. Viral antigens were fixed to the surface of microtiter wells, and serial dilutions of antiviral antibody were added. The amount of antiviral antibody bound to viral antigens was determined by measuring the extent to which the antiviral antibody either inhibited the specific binding of (125)I-labeled antiviral immunoglobulin G (IgG) (direct technique) or enhanced the specific binding of (125)I-labeled anti-IgG (indirect technique). Immune complexes composed of viral antigens and antiviral antibody (human) could be detected by the binding of (125)I-labeled rheumatoid factor. Specific binding was influenced by the concentration of protein in the diluents used during the different steps of the procedure. A high concentration of protein in the diluent used with the viral antigens decreased specific binding, whereas a high concentration of protein in the diluent used with (125)I-labeled anti-IgG increased specific binding by decreasing nonspecific attachment of the labeled anti-IgG. Under the conditions employed, the titer of a given antiviral serum was several hundredfold greater by the indirect than by the direct technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349247"}
{"pmid": "4349248", "title": "Quantitative assessment of hemadsorption by myxoviruses: virus hemadsorption assay.", "content": "Quantitative assessment of hemadsorption by myxoviruses: virus hemadsorption assay. The standardization and quantitative evaluation of an assay for myxoviruses, based on the enumeration of individual infected clone 1-5C-4 cells manifesting hemadsorption within 24 h of infection, are described. Hemadsorption was detectable earlier than immunofluorescence in infected cells or hemagglutinins in culture medium. The relationship between virus concentration and cells exhibiting hemadsorption was linear. The assay was highly precise, sensitive, and reproducible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349248"}
{"pmid": "4349249", "title": "Quantitative assessment of hemadsorption by myxoviruses: anti-immunoglobulin G hemadsorption-inhibition test.", "content": "Quantitative assessment of hemadsorption by myxoviruses: anti-immunoglobulin G hemadsorption-inhibition test. A quantitative hemadsorption-inhibition test was developed to estimate myxovirus serum antibodies within 24 h by determining the serum dilution inhibiting hemadsorption in 50% of the infected cells. The test depends on the interactions of virus-infected cell monolayers with antiviral serum and of the resultant complexes with antiimmunoglobulin G serum. The incorporation of species-specific anti-immunoglobulin G serum into the test significantly increased sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349249"}
{"pmid": "4349251", "title": "Experience with an image-analyzing computer in virus plaque measurements.", "content": "Experience with an image-analyzing computer in virus plaque measurements. Due to the extremely fast and reliable plaque-number determinations, the image-analyzing computer is most useful for large screening programs involving plaque-reduction tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349251"}
{"pmid": "4349252", "title": "Fish viruses: buffers and methods for plaquing eight agents under normal atmosphere.", "content": "Fish viruses: buffers and methods for plaquing eight agents under normal atmosphere. A universal procedure was sought for plaque assay of eight fish viruses (bluegill myxovirus, channel catfish virus, eel virus, Egtved virus, infectious hematopoietic necrosis virus, infectious pancreatic necrosis virus, lymphocystis virus, and the agent of spring viremia of carp (Rhabdovirus carpio), in dish cultures of various fish cells. Eagle minimal essential medium with sodium bicarbonate-CO(2) buffer (Earle's salt solution) was compared with minimal essential medium buffered principally with tris (hydroxymethyl)aminomethane or N-2-hydroxyethylpiperazine-N'-2'-ethanesulfonic acid at a pH or in the range of 7.6 to 8.0 depending upon temperature. Five fish cell lines collectively capable of replicating all fish viruses thus far isolated were tested and quantitatively found to grow comparably well in the three media. Two-phase (gel-liquid) media incorporating the various buffer systems allowed plaquing at 15 to 33 C either in partial pressures of CO(2) or in normal atmosphere, but greater efficiency and sensitivity were obtained with the organic buffers, and, overall, the best results were obtained with tris(hydroxymethyl)aminomethane. Epizootiological data, specific fish cell line response, and plaque morphology permit presumptive identification of most of the agents. At proper pH, use of organic buffers obviates the need for CO(2) incubators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349252"}
{"pmid": "4349253", "title": "Nuclear magnetic resonance studies of alcohol dehydrogenases. Binding of inhibitors to the yeast and liver enzymes.", "content": "Nuclear magnetic resonance studies of alcohol dehydrogenases. Binding of inhibitors to the yeast and liver enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349253"}
{"pmid": "4349250", "title": "Flocculant and chemical properties of a polysaccharide from Pullularia pullulans.", "content": "Flocculant and chemical properties of a polysaccharide from Pullularia pullulans. An extracellular polysaccharide, PP-floc, was synthesized from glucose by Pullularia pullulans (or Aureobasidium pullulans) in a pilot plant batch fermentor containing 175 liters of culture medium. At 58 h of fermentation, the concentration of PP-floc was 1.03 g/100 ml, giving a 25.8% conversion of initial glucose to polysaccharide. The flocculant activity of the culture medium increased during the fermentation process and reached its maximum at 50 h of culture age. Less PP-floc (0.33 lb/ton of slimes [approximately 149.7 g/0.907 t]) was required to give the same flocculant activity as a synthetic polymer of acrylamide, Separan NP-10 (0.5 lb/ton of slimes [approximately 226.8 g/0.907 t]), at all temperatures from 25 to 100 C. The degree of inactivation of PP-floc and Separan NP-10 at elevated temperatures was almost identical, and they were completely inactivated at about the same temperature (80 C). PP-floc also gave better compaction of slimes than Separan NP-10 at all temperatures tested. PP-floc was soluble in water and its specific optical rotation was [alpha](D) (25) + 194 degrees in water (c, 0.4). PP-floc contained 83.3% carbohydrate, 3.2% protein, and 8.1% water. Glucose was found to be the principal sugar monomer with traces (>5%) of galactose and mannose present. Structural studies on the fractions of purified polysaccharide by methylation and by periodate oxidation techniques prove that PP-floc is linear and composed of alpha-(1 --> 4) and alpha-(1 --> 6) glucopyranosyl units in the approximate ratio of 2:1. The action of pullulanase on crude PP-floc suggested the ordered arrangement of two consecutive alpha-(1 --> 4)-linked glucopyranosyl units flanked by alpha-(1 --> 6)-linked glucopyranose residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349250"}
{"pmid": "4349254", "title": "Interaction of chloride ion with horse liver alcohol dehydrogenase-reduced nicotinamide adenine dinucleotide complexes.", "content": "Interaction of chloride ion with horse liver alcohol dehydrogenase-reduced nicotinamide adenine dinucleotide complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349254"}
{"pmid": "4349255", "title": "Simultaneous binding of competitive ligands to horse liver alcohol dehydrogenase.", "content": "Simultaneous binding of competitive ligands to horse liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349255"}
{"pmid": "4349257", "title": "Spectroscopic and magnetic studies of iron (3) phosvitins.", "content": "Spectroscopic and magnetic studies of iron (3) phosvitins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349257"}
{"pmid": "4349256", "title": "In vitro adenylylation of lysine-sensitive aspartylkinase from Escherichia coli TIR-8.", "content": "In vitro adenylylation of lysine-sensitive aspartylkinase from Escherichia coli TIR-8.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349256"}
{"pmid": "4349258", "title": "A complex of cytochrome c and mixed mitochondrial phospholipids.", "content": "A complex of cytochrome c and mixed mitochondrial phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349258"}
{"pmid": "4349259", "title": "Cofactor activity of protein components of human very low density lipoproteins in the hydrolysis of triglycerides by lipoproteins lipase from different sources.", "content": "Cofactor activity of protein components of human very low density lipoproteins in the hydrolysis of triglycerides by lipoproteins lipase from different sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349259"}
{"pmid": "4349260", "title": "Rapid two-channel microfluorimetry: a method for comparative study of metabolism, phase differences or transport in the cytoplasm and nucleus.", "content": "Rapid two-channel microfluorimetry: a method for comparative study of metabolism, phase differences or transport in the cytoplasm and nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349260"}
{"pmid": "4349261", "title": "The purification of lysosomes from HeLa cells by centrifugation in colloidal silica density gradients.", "content": "The purification of lysosomes from HeLa cells by centrifugation in colloidal silica density gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349261"}
{"pmid": "4349262", "title": "Magnetic properties of potassium dithioferrate: a linear chain antiferromagnet and model compound for the exchange interactions in two-iron ferredoxins.", "content": "Magnetic properties of potassium dithioferrate: a linear chain antiferromagnet and model compound for the exchange interactions in two-iron ferredoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349262"}
{"pmid": "4349263", "title": "On the mechanism of superoxide dismutase. Reaction of the bovine enzyme with hydrogen peroxide and ferrocyanide.", "content": "On the mechanism of superoxide dismutase. Reaction of the bovine enzyme with hydrogen peroxide and ferrocyanide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349263"}
{"pmid": "4349264", "title": "The reaction of nitric oxide with ceruloplasmin.", "content": "The reaction of nitric oxide with ceruloplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349264"}
{"pmid": "4349265", "title": "Adenosine 3',5'-monophosphate-dependent protein kinase of bovine tracheal smooth muscle.", "content": "Adenosine 3',5'-monophosphate-dependent protein kinase of bovine tracheal smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349265"}
{"pmid": "4349266", "title": "The phytases. II. Properties of phytase fractions F 1  and F 2  from wheat bran and the myoinositol phosphates produced by fraction F 2 .", "content": "The phytases. II. Properties of phytase fractions F 1  and F 2  from wheat bran and the myoinositol phosphates produced by fraction F 2 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349266"}
{"pmid": "4349267", "title": "The metabolic and endocrine response to injury: a review.", "content": "The metabolic and endocrine response to injury: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349267"}
{"pmid": "4349268", "title": "Cerebral metabolic effects of hyperventilation and deliberate hypotension.", "content": "Cerebral metabolic effects of hyperventilation and deliberate hypotension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349268"}
{"pmid": "4349269", "title": "Effects of anaesthetic agents on metabolic pathways: fuel utilization and supply during anaesthesia.", "content": "Effects of anaesthetic agents on metabolic pathways: fuel utilization and supply during anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349269"}
{"pmid": "4349270", "title": "Endocrine responses to anaesthetic agents.", "content": "Endocrine responses to anaesthetic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349270"}
{"pmid": "4349272", "title": "Indirect inhibition of the biosynthesis of 1,25-dihydroxycholecalciferol in rats treated with a diphosphonate.", "content": "Indirect inhibition of the biosynthesis of 1,25-dihydroxycholecalciferol in rats treated with a diphosphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349272"}
{"pmid": "4349274", "title": "Two sites of cardiovascular action of angiotensin II in the brain of the dog.", "content": "Two sites of cardiovascular action of angiotensin II in the brain of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349274"}
{"pmid": "4349273", "title": "Plasma volume, extracellular fluid volume and exchangeable sodium concentrations in the New Zealand strain of genetically hypertensive rat.", "content": "Plasma volume, extracellular fluid volume and exchangeable sodium concentrations in the New Zealand strain of genetically hypertensive rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349273"}
{"pmid": "4349275", "title": "A preliminary attempt to measure continuity of care in a community mental health center.", "content": "A preliminary attempt to measure continuity of care in a community mental health center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349275"}
{"pmid": "4349276", "title": "Evaluation of chronic pain in children.", "content": "Evaluation of chronic pain in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349276"}
{"pmid": "4349277", "title": "The pathophysiology of pain.", "content": "The pathophysiology of pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349277"}
{"pmid": "4349279", "title": "Problems of information processing in the nervous system.", "content": "Problems of information processing in the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349279"}
{"pmid": "4349280", "title": "Transfer of information within the cockroach central nervous system during shock avoidance learning: is there a nerve impulse code(s) for learned information?", "content": "Transfer of information within the cockroach central nervous system during shock avoidance learning: is there a nerve impulse code(s) for learned information?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349280"}
{"pmid": "4349281", "title": "Medical schools and teaching hospitals should become involved in development and operation of PSROs.", "content": "Medical schools and teaching hospitals should become involved in development and operation of PSROs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349281"}
{"pmid": "4349282", "title": "An electrophysiological investigation of skeletal muscle in Parkinson's disease.", "content": "An electrophysiological investigation of skeletal muscle in Parkinson's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349282"}
{"pmid": "4349283", "title": "Ultrastructure of a human spinal neuroma.", "content": "Ultrastructure of a human spinal neuroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349283"}
{"pmid": "4349284", "title": "Amyloidosis.", "content": "Amyloidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349284"}
{"pmid": "4349285", "title": "Gout.", "content": "Gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349285"}
{"pmid": "4349286", "title": "Chondrocalcinosis and pseudogout.", "content": "Chondrocalcinosis and pseudogout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349286"}
{"pmid": "4349287", "title": "Primary neoplasms of joints.", "content": "Primary neoplasms of joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349287"}
{"pmid": "4349293", "title": "Single fibre EMG in juvenile myasthenia gravis.", "content": "Single fibre EMG in juvenile myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349293"}
{"pmid": "4349294", "title": "The relationship between maternal and neonatal sleep.", "content": "The relationship between maternal and neonatal sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349294"}
{"pmid": "4349295", "title": "Eye movements in infants using DC recording.", "content": "Eye movements in infants using DC recording.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349295"}
{"pmid": "4349296", "title": "Involvement of sural nerve in neuronal ceroid-lipofuscinoses: report of two cases.", "content": "Involvement of sural nerve in neuronal ceroid-lipofuscinoses: report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349296"}
{"pmid": "4349297", "title": "Papaverine antagonism of prostaglandin E 2 -induced contraction of rabbit aortic strips.", "content": "Papaverine antagonism of prostaglandin E 2 -induced contraction of rabbit aortic strips.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349297"}
{"pmid": "4349288", "title": "Mechanism of the enzymatic reaction catalyzed by UDPG dehydrogenase. I. Study of the initial rate and kinetic mechanism of the reaction.", "content": "Mechanism of the enzymatic reaction catalyzed by UDPG dehydrogenase. I. Study of the initial rate and kinetic mechanism of the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349288"}
{"pmid": "4349299", "title": "Effect of theophylline on alkaline phosphatase activity of denervated skeletal muscle fibers.", "content": "Effect of theophylline on alkaline phosphatase activity of denervated skeletal muscle fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349299"}
{"pmid": "4349298", "title": "Sex-dependent effects of cyclic AMP on the hepatic mixed function oxidase system.", "content": "Sex-dependent effects of cyclic AMP on the hepatic mixed function oxidase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349298"}
{"pmid": "4349290", "title": "Investigation of conformational transitions of cytochrome c by the spin-tag method.", "content": "Investigation of conformational transitions of cytochrome c by the spin-tag method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349290"}
{"pmid": "4349289", "title": "Investigation of electrostatic charges in proteins by the paramagnetic probe method.", "content": "Investigation of electrostatic charges in proteins by the paramagnetic probe method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349289"}
{"pmid": "4349292", "title": "The secondary structure of collagenase.", "content": "The secondary structure of collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349292"}
{"pmid": "4349291", "title": "Modification of E. coli B RNA-polymerase by 2,2,6,6-tetramethyl-4-chloromercuricarbobenzoxypiperidine-1-oxyl.", "content": "Modification of E. coli B RNA-polymerase by 2,2,6,6-tetramethyl-4-chloromercuricarbobenzoxypiperidine-1-oxyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349291"}
{"pmid": "4349311", "title": "Cyclic AMP.", "content": "Cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349311"}
{"pmid": "4349312", "title": "Collagenase debridement.", "content": "Collagenase debridement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349312"}
{"pmid": "4349313", "title": "Rural emergency psychiatric services.", "content": "Rural emergency psychiatric services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349313"}
{"pmid": "4349315", "title": "Immunohistochemical and histochemical studies of pituitary beta-lipotrophs.", "content": "Immunohistochemical and histochemical studies of pituitary beta-lipotrophs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349315"}
{"pmid": "4349306", "title": "Cytology of diffuse liver disorders.", "content": "Cytology of diffuse liver disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349306"}
{"pmid": "4349304", "title": "Inclusion bodies in cells from a hydatidiform mole.", "content": "Inclusion bodies in cells from a hydatidiform mole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349304"}
{"pmid": "4349305", "title": "Intranuclear cytoplasmic inclusions in some types of thyroid cancer.", "content": "Intranuclear cytoplasmic inclusions in some types of thyroid cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349305"}
{"pmid": "4349317", "title": "A Novel function of cytochrome C (555, Chlorobium thiosulfatophilum) in oxidation of thiosulfate.", "content": "A Novel function of cytochrome C (555, Chlorobium thiosulfatophilum) in oxidation of thiosulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349317"}
{"pmid": "4349316", "title": "Cytochrome oxidase and NADH cytochrome c. Reductase distribution during skin wound healing in rats of various ages.", "content": "Cytochrome oxidase and NADH cytochrome c. Reductase distribution during skin wound healing in rats of various ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349316"}
{"pmid": "4349318", "title": "Diadenosine tetraphosphate splitting by rat liver extracts.", "content": "Diadenosine tetraphosphate splitting by rat liver extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349318"}
{"pmid": "4349319", "title": "An alternate enzymic route for the synthesis of the alkyl analog of phosphatidic acid involving alkylglycerol.", "content": "An alternate enzymic route for the synthesis of the alkyl analog of phosphatidic acid involving alkylglycerol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349319"}
{"pmid": "4349307", "title": "Cytologic changes of the respiratory tract in young adults as a consequence of high levels of air pollution exposure.", "content": "Cytologic changes of the respiratory tract in young adults as a consequence of high levels of air pollution exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349307"}
{"pmid": "4349320", "title": "Clustering of lecithin molecules in phosphatidylserine membranes induced by calcium ion binding to phosphatidylserine.", "content": "Clustering of lecithin molecules in phosphatidylserine membranes induced by calcium ion binding to phosphatidylserine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349320"}
{"pmid": "4349308", "title": "Bronchial brushing technique for the cytologic diagnosis of peripheral lung lesions. A review of 693 cases.", "content": "Bronchial brushing technique for the cytologic diagnosis of peripheral lung lesions. A review of 693 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349308"}
{"pmid": "4349309", "title": "Cytologic detection of vaginal parasitosis.", "content": "Cytologic detection of vaginal parasitosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349309"}
{"pmid": "4349323", "title": "Incorporation in vitro of purified cytochrome b 5  into liver microsomal membranes.", "content": "Incorporation in vitro of purified cytochrome b 5  into liver microsomal membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349323"}
{"pmid": "4349321", "title": "On the structure of NADH-X.", "content": "On the structure of NADH-X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349321"}
{"pmid": "4349322", "title": "The effect of starvation on tissue adenosine 3'-5' monophosphate levels.", "content": "The effect of starvation on tissue adenosine 3'-5' monophosphate levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349322"}
{"pmid": "4349325", "title": "Reversible inactivation by NADH and ADP on Chlorella fusca nitrate reductase.", "content": "Reversible inactivation by NADH and ADP on Chlorella fusca nitrate reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349325"}
{"pmid": "4349324", "title": "Ribonuclease H activity present in purified DNA polymerase from avian myeloblastosis virus.", "content": "Ribonuclease H activity present in purified DNA polymerase from avian myeloblastosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349324"}
{"pmid": "4349326", "title": "Fluorescence studies of a cytochrome C mixed phospholipid complex.", "content": "Fluorescence studies of a cytochrome C mixed phospholipid complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349326"}
{"pmid": "4349327", "title": "Heme modification studies of myoglobin. I. Purification and some optical and EPR characteristics of synthesized myoglobins containing unnatural hemes.", "content": "Heme modification studies of myoglobin. I. Purification and some optical and EPR characteristics of synthesized myoglobins containing unnatural hemes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349327"}
{"pmid": "4349328", "title": "Kinetics and equilbria among the multiple forms of ferricytochrome.", "content": "Kinetics and equilbria among the multiple forms of ferricytochrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349328"}
{"pmid": "4349314", "title": "Are stages of sleep related to waking behavior?", "content": "Are stages of sleep related to waking behavior?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349314"}
{"pmid": "4349329", "title": "The effect of the sialyl residues on the thermodynamic and hydrodynamic properties of   1 -acid glycoprotein.", "content": "The effect of the sialyl residues on the thermodynamic and hydrodynamic properties of   1 -acid glycoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349329"}
{"pmid": "4349330", "title": "A rat-specific lysine-rich histone.", "content": "A rat-specific lysine-rich histone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349330"}
{"pmid": "4349331", "title": "Alkaline sucrose sedimentation studies of DNA from P388F lymphoma cells treated with disfunctional alkylating agents.", "content": "Alkaline sucrose sedimentation studies of DNA from P388F lymphoma cells treated with disfunctional alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349331"}
{"pmid": "4349332", "title": "Differences in the transfer RNA methyltransferases from normal rat liver and Novikoff hepatoma.", "content": "Differences in the transfer RNA methyltransferases from normal rat liver and Novikoff hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349332"}
{"pmid": "4349333", "title": "Structural analyses of mammalian ribosomal ribonucleic acid and its precursors. The distribution of polypyrimidine sequences in ribosomal 18-S RNA.", "content": "Structural analyses of mammalian ribosomal ribonucleic acid and its precursors. The distribution of polypyrimidine sequences in ribosomal 18-S RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349333"}
{"pmid": "4349334", "title": "Value of an ACTH test in assessing hypothalamic-pituitary-adrenocortical function in glucocorticoid-treated patients.", "content": "Value of an ACTH test in assessing hypothalamic-pituitary-adrenocortical function in glucocorticoid-treated patients. Forty-eight patients receiving glucocorticoid treatment were tested with ACTH stimulation using alpha(1, 24) ACTH (tetracosactrin). All patients subsequently underwent non-acute major surgery without any glucocorticoid administration, and their clinical course and plasma corticosteroids were followed closely. No case of adrenocortical insufficiency was observed. A highly significant correlation was found between the pre-operative adrenocortical response to ACTH and the hypothalmic-pituitary-adrenocortical (H.P.A.) response to surgery. A normal response to ACTH stimulation was never followed by a greatly impaired H.P.A. response to surgery. It seems that a simple ACTH stimulation test is reliable in predicting the integrated H.P.A. response to major stress in glucocorticoid-treated patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349334"}
{"pmid": "4349335", "title": "Persistence of tanapox in Tana River valley.", "content": "Persistence of tanapox in Tana River valley. Sera collected from inhabitants of the Tana River valley in 1971 were examined for antibody to tanapox virus. Neutralizing antibody was present in 16.3%. The levels of antibody and its presence in two children under the age of 10 years indicated that infection had been occurring in the area since the reported outbreak in 1962. A comparison of the incidence and distribution of antibodies in the same sera to West Nile virus revealed marked similarities suggesting that tanapox, like West Nile virus infections, might be transmitted in the same way-namely, by a culicine mosquito.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349335"}
{"pmid": "4349336", "title": "Outbreak in Bristol of conjunctivitis caused by adenovirus type 8, and its epidemiology and control.", "content": "Outbreak in Bristol of conjunctivitis caused by adenovirus type 8, and its epidemiology and control. In an investigation of an outbreak of adenovirus type 8 infection involving over 40 people it was found that the infection spread initially within the eye hospital, but subsequently involved several family contacts and two local hospitals for mentally subnormal patients. Presumptive diagnosis should be possible before subepithelial opacities have developed provided an adequate history is taken, and had that been done in this outbreak it is reasonable to suppose that many cases could have been prevented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349336"}
{"pmid": "4349337", "title": "Enterovirus infections.", "content": "Enterovirus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349337"}
{"pmid": "4349338", "title": "Zollinger-Ellison syndrome reclassified.", "content": "Zollinger-Ellison syndrome reclassified.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349338"}
{"pmid": "4349339", "title": "A spin probe study of the influence of cholesterol on motion and orientation of phospholipids in oriented multibilayers and vesicles.", "content": "A spin probe study of the influence of cholesterol on motion and orientation of phospholipids in oriented multibilayers and vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349339"}
{"pmid": "4349340", "title": "Effects of intravenous neuraminidase on the turnover of fibrinogen.", "content": "Effects of intravenous neuraminidase on the turnover of fibrinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349340"}
{"pmid": "4349341", "title": "Studies with a mass balance method of measuring fibrinogen synthesis.", "content": "Studies with a mass balance method of measuring fibrinogen synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349341"}
{"pmid": "4349342", "title": "Future developments in prophylaxis.", "content": "Future developments in prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349342"}
{"pmid": "4349343", "title": "Intrauterine infections: chairman's summary.", "content": "Intrauterine infections: chairman's summary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349343"}
{"pmid": "4349344", "title": "Congenital cytomegalovirus infections.", "content": "Congenital cytomegalovirus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349344"}
{"pmid": "4349345", "title": "Foetal interferon responses induced by rubella virus.", "content": "Foetal interferon responses induced by rubella virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349345"}
{"pmid": "4349346", "title": "Serum lipoprotein patterns in patients with coronary atherosclerosis.", "content": "Serum lipoprotein patterns in patients with coronary atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349346"}
{"pmid": "4349347", "title": "Choice of conditions for the gradient flotation of serum lipoproteins in swing-out rotors.", "content": "Choice of conditions for the gradient flotation of serum lipoproteins in swing-out rotors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349347"}
{"pmid": "4349348", "title": "Pathological effects of lead.", "content": "Pathological effects of lead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349348"}
{"pmid": "4349349", "title": "The role of renal factors in the pathogenesis of experimental hypertension.", "content": "The role of renal factors in the pathogenesis of experimental hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349349"}
{"pmid": "4349350", "title": "Ultrastructural alterations in X-irradiated epidermis.", "content": "Ultrastructural alterations in X-irradiated epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349350"}
{"pmid": "4349351", "title": "An ultrastructural study of embryonal rhabdomyosarcoma (Sarcoma botryoides) of the bladder.", "content": "An ultrastructural study of embryonal rhabdomyosarcoma (Sarcoma botryoides) of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349351"}
{"pmid": "4349352", "title": "Studies on the neutralization of herpes simplex virus. VI. The mode of action of complement upon antibodysensitized virus.", "content": "Studies on the neutralization of herpes simplex virus. VI. The mode of action of complement upon antibodysensitized virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349352"}
{"pmid": "4349354", "title": "Plaque formation by herpes simplex virus in established calf kidney cells.", "content": "Plaque formation by herpes simplex virus in established calf kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349354"}
{"pmid": "4349353", "title": "Origin of thymidine kinase in the cells infected with infectious canine hepatitis virus.", "content": "Origin of thymidine kinase in the cells infected with infectious canine hepatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349353"}
{"pmid": "4349355", "title": "Adenovirus infection in intussusception of Japanese infants.", "content": "Adenovirus infection in intussusception of Japanese infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349355"}
{"pmid": "4349357", "title": "Stimulation by cyclic AMP and ppGpp of chloramphenicol acetyl transferase synthesis.", "content": "Stimulation by cyclic AMP and ppGpp of chloramphenicol acetyl transferase synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349357"}
{"pmid": "4349356", "title": "Narcolepsy.", "content": "Narcolepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349356"}
{"pmid": "4349358", "title": "Phospholipid incorporation into plasma membrane of lactating mammary cell with special reference to sphingomyelin.", "content": "Phospholipid incorporation into plasma membrane of lactating mammary cell with special reference to sphingomyelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349358"}
{"pmid": "4349359", "title": "Australian tiger snake venom--an inhibitor of transmitter release.", "content": "Australian tiger snake venom--an inhibitor of transmitter release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349359"}
{"pmid": "4349360", "title": "Effect of lysine vasopressin and ACTH 4-10  on conditioned avoidance behavior of hypophysectomized rats.", "content": "Effect of lysine vasopressin and ACTH 4-10  on conditioned avoidance behavior of hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349360"}
{"pmid": "4349361", "title": "Effect of stress and hypothalamic deafferentation on the secretion of growth hormone in the rat.", "content": "Effect of stress and hypothalamic deafferentation on the secretion of growth hormone in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349361"}
{"pmid": "4349362", "title": "Evidence for a diurnal fluctuation in plasma corticosterone levels after fornix transection in the rat.", "content": "Evidence for a diurnal fluctuation in plasma corticosterone levels after fornix transection in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349362"}
{"pmid": "4349363", "title": "Basal-cell adenoma of the upper lip. Report of a case.", "content": "Basal-cell adenoma of the upper lip. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349363"}
{"pmid": "4349364", "title": "Malignant fibrous histiocytoma of the soft tissues of the mandible.", "content": "Malignant fibrous histiocytoma of the soft tissues of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349364"}
{"pmid": "4349367", "title": "Metabolism of ethanol and its effects upon the liver.", "content": "Metabolism of ethanol and its effects upon the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349367"}
{"pmid": "4349368", "title": "Electron spin resonance and pulse radiolysis studies of irradiated aqueous solutions of 5-nitrouracils. Oxidative denitration by OH radicals.", "content": "Electron spin resonance and pulse radiolysis studies of irradiated aqueous solutions of 5-nitrouracils. Oxidative denitration by OH radicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349368"}
{"pmid": "4349371", "title": "Endocrine liver tumours.", "content": "Endocrine liver tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349371"}
{"pmid": "4349372", "title": "Carcinoma in a Hamman-Rich lung. A case report.", "content": "Carcinoma in a Hamman-Rich lung. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349372"}
{"pmid": "4349373", "title": "Angiotensin, aldosterone and DOC in hypertensive disease of pregnancy.", "content": "Angiotensin, aldosterone and DOC in hypertensive disease of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349373"}
{"pmid": "4349378", "title": "\"Fingerprint inclusions\" in muscle fibres in dystrophia myotonica.", "content": "\"Fingerprint inclusions\" in muscle fibres in dystrophia myotonica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349378"}
{"pmid": "4349379", "title": "Mechanism of demyelination in JHM virus encephalomyelitis. Electron microscopic studies.", "content": "Mechanism of demyelination in JHM virus encephalomyelitis. Electron microscopic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349379"}
{"pmid": "4349380", "title": "A piezoelectric cascade impactor for aerosol monitoring.", "content": "A piezoelectric cascade impactor for aerosol monitoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349380"}
{"pmid": "4349381", "title": "The digestion of lung tissue for mineral dust recovery.", "content": "The digestion of lung tissue for mineral dust recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349381"}
{"pmid": "4349383", "title": "Spontaneous regression of a putative childhood hepatoma. A reappraisal.", "content": "Spontaneous regression of a putative childhood hepatoma. A reappraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349383"}
{"pmid": "4349382", "title": "Growth in children following renal transplantation.", "content": "Growth in children following renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349382"}
{"pmid": "4349384", "title": "An alternative in trophoblastic disease follow-up.", "content": "An alternative in trophoblastic disease follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349384"}
{"pmid": "4349385", "title": "Taurodont, pyramidal and fused molar roots associated with other anomalies in a kindred.", "content": "Taurodont, pyramidal and fused molar roots associated with other anomalies in a kindred.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349385"}
{"pmid": "4349386", "title": "Growth and skeletal maturation in British Columbia Indian Populations.", "content": "Growth and skeletal maturation in British Columbia Indian Populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349386"}
{"pmid": "4349387", "title": "Carpal tunnel syndrome in rheumatoid arthritis.", "content": "Carpal tunnel syndrome in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349387"}
{"pmid": "4349388", "title": "Primary malignant tumors of the esophagus other than typical epidermoid carcinoma.", "content": "Primary malignant tumors of the esophagus other than typical epidermoid carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349388"}
{"pmid": "4349390", "title": "Biological activity of 2-phenylethanol and its derivatives. 8. Influence on herpesvirus DNA-synthesis in rabbit kidney cells.", "content": "Biological activity of 2-phenylethanol and its derivatives. 8. Influence on herpesvirus DNA-synthesis in rabbit kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349390"}
{"pmid": "4349391", "title": "In situ fragmentation of RNA in poliovirus.", "content": "In situ fragmentation of RNA in poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349391"}
{"pmid": "4349393", "title": "Thermosensitive events in adenovirus transformed cells. II. Helping of adenovirus-associated viruses.", "content": "Thermosensitive events in adenovirus transformed cells. II. Helping of adenovirus-associated viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349393"}
{"pmid": "4349392", "title": "Thermosensitive events in adenovirus transformed cells. I. Resistance to herpes simplex virus.", "content": "Thermosensitive events in adenovirus transformed cells. I. Resistance to herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349392"}
{"pmid": "4349394", "title": "Effect of phleomycin on the replication of mengovirus in novikoff hepatoma cells.", "content": "Effect of phleomycin on the replication of mengovirus in novikoff hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349394"}
{"pmid": "4349395", "title": "Interferon induction by rice dwarf virus RNA. Antiviral activity in vitro and its stability.", "content": "Interferon induction by rice dwarf virus RNA. Antiviral activity in vitro and its stability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349395"}
{"pmid": "4349396", "title": "DEAE-dextran enhancement of in vivo infection with murine leukemia virus.", "content": "DEAE-dextran enhancement of in vivo infection with murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349396"}
{"pmid": "4349397", "title": "Ultrastructural study on the sequence of human cytomegalovirus infection in human diploid cells.", "content": "Ultrastructural study on the sequence of human cytomegalovirus infection in human diploid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349397"}
{"pmid": "4349400", "title": "Lyophilization of varicella virus. Brief report.", "content": "Lyophilization of varicella virus. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349400"}
{"pmid": "4349399", "title": "Experimental corneal infection of the cebus monkey with herpesvirus hominis type 1 and type 2.", "content": "Experimental corneal infection of the cebus monkey with herpesvirus hominis type 1 and type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349399"}
{"pmid": "4349401", "title": "Hypertension with adrenal, genital, renal defects, and deafness. A new familial syndrome.", "content": "Hypertension with adrenal, genital, renal defects, and deafness. A new familial syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349401"}
{"pmid": "4349402", "title": "The substitution of corticotrophin for corticosteroid in the treatment of children and adults with chronic asthma.", "content": "The substitution of corticotrophin for corticosteroid in the treatment of children and adults with chronic asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349402"}
{"pmid": "4349403", "title": "Glomus jugulare tumour: a case report.", "content": "Glomus jugulare tumour: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349403"}
{"pmid": "4349405", "title": "Kinetics of refolding of guanidine hydrochloride denatured cytochrome c. Temperature dependence.", "content": "Kinetics of refolding of guanidine hydrochloride denatured cytochrome c. Temperature dependence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349405"}
{"pmid": "4349404", "title": "Monkeypox virus.", "content": "Monkeypox virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349404"}
{"pmid": "4349406", "title": "Synthesis, biological activity, and  19 F nuclear magnetic resonance spectra of angiotensin II analogs containing fluorine.", "content": "Synthesis, biological activity, and  19 F nuclear magnetic resonance spectra of angiotensin II analogs containing fluorine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349406"}
{"pmid": "4349407", "title": "Measurement of fast lateral diffusion of lipids in vesicles and in biological membranes by  1 H nuclear magnetic resonance.", "content": "Measurement of fast lateral diffusion of lipids in vesicles and in biological membranes by  1 H nuclear magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349407"}
{"pmid": "4349408", "title": "Stimulation of renal gluconeogenesis by inhibition of the sodium pump.", "content": "Stimulation of renal gluconeogenesis by inhibition of the sodium pump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349408"}
{"pmid": "4349409", "title": "Effects of catecholamines on ammoniagenesis and gluconeogenesis by renal cortex in vitro.", "content": "Effects of catecholamines on ammoniagenesis and gluconeogenesis by renal cortex in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349409"}
{"pmid": "4349410", "title": "Preovulatory changes in the synthesis of cyclic AMP by rabbit Graafian follicles.", "content": "Preovulatory changes in the synthesis of cyclic AMP by rabbit Graafian follicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349410"}
{"pmid": "4349411", "title": "Structural studies on avian myeloblastosis virus: conditions for isolation and biochemical characteristics of the core component.", "content": "Structural studies on avian myeloblastosis virus: conditions for isolation and biochemical characteristics of the core component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349411"}
{"pmid": "4349412", "title": "Hormone- and fluoride-sensitive adenylate cyclases in human fetal tissues.", "content": "Hormone- and fluoride-sensitive adenylate cyclases in human fetal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349412"}
{"pmid": "4349413", "title": "Studies on a peptidase acting on a synthetic collagenase substrate. Developmental pattern in rat granuloma tissue and distribution of enzyme in the tissues of various animals.", "content": "Studies on a peptidase acting on a synthetic collagenase substrate. Developmental pattern in rat granuloma tissue and distribution of enzyme in the tissues of various animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349413"}
{"pmid": "4349414", "title": "Two anti-anxiety drugs: a psychoneuroendocrine study.", "content": "Two anti-anxiety drugs: a psychoneuroendocrine study. Eight males were studied during 27 weeks, including two periods of five weeks during which they received clinical doses of sodium amylobarbitone and benzoctamine. Substitution of placebo for either drug caused raised anxiety and impairment of mental concentration. The drugs reduced restlessness during sleep and reduced paradoxical sleep. By the fifth week of sodium amylobarbitone, although sleep was still less restless in the early night it was more restless than normal in the late night.Blood samples were taken half-hourly during sleep by indwelling venous catheter. Plasma growth hormone concentration was little affected during drug administration but rose temporarily after withdrawal. There was a reduction of plasma corticosteroid concentration during sleep throughout administration of the drugs and a rebound above normal during the first withdrawal week.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349414"}
{"pmid": "4349415", "title": "Acute respiratory virus infections.", "content": "Acute respiratory virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349415"}
{"pmid": "4349416", "title": "Clarke's column and the dorsal spinocerebellar tract: a review.", "content": "Clarke's column and the dorsal spinocerebellar tract: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349416"}
{"pmid": "4349418", "title": "Critical periods in brain development. In: lipids, malnutrition & the developing brain.", "content": "Critical periods in brain development. In: lipids, malnutrition & the developing brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349418"}
{"pmid": "4349419", "title": "The phylogenetic evolution of the corneal stroma. Distribution of carbohydrates in the macromolecular complexes of the primate baboon (Cynocephalus papio-papio) corneal stroma.", "content": "The phylogenetic evolution of the corneal stroma. Distribution of carbohydrates in the macromolecular complexes of the primate baboon (Cynocephalus papio-papio) corneal stroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349419"}
{"pmid": "4349420", "title": "Studies on enzymes from parasitic helminths. 3. Purification and properties of lactate dehydrogenase from the tapeworm, Hymenolepis diminuta.", "content": "Studies on enzymes from parasitic helminths. 3. Purification and properties of lactate dehydrogenase from the tapeworm, Hymenolepis diminuta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349420"}
{"pmid": "4349421", "title": "Temperature-sensitive mutations in Drosophila melanogaster. XII. The genetic and developmental effects of dominant lethals on chromosome 3.", "content": "Temperature-sensitive mutations in Drosophila melanogaster. XII. The genetic and developmental effects of dominant lethals on chromosome 3. Out of 25,000 EMS-treated third chromosomes examined, ten dominant temperature-sensitive (DTS) lethal mutations which are lethal when heterozygous at 29 degrees C but survive at 22 degrees C were recovered. Seven of the eight mutations mapped were tested for complementation; these mutants probably define eight loci. Only DTS-2 survived in homozygous condition at 22 degrees C; homozygous DTS-2 females expressed a maternal effect on embryonic viability. Two of the mutant-bearing chromosomes, DTS-1 and DTS-6, exhibited dominant phenotypes similar to those associated with Minutes. Each of the seven mutants examined exhibited a characteristic phenotype with respect to the time of death at 29 degrees C and the temperature-sensitive period during development. Only DTS-4 exhibited dominant lethality in triploid females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349421"}
{"pmid": "4349422", "title": "Methadone in a 30-day detoxification program for narcotic addicts: a critical review.", "content": "Methadone in a 30-day detoxification program for narcotic addicts: a critical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349422"}
{"pmid": "4349423", "title": "Action in primary afferent fibers in the spinal cord.", "content": "Action in primary afferent fibers in the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349423"}
{"pmid": "4349424", "title": "A mode control model of a neuron's axon and dendrites.", "content": "A mode control model of a neuron's axon and dendrites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349424"}
{"pmid": "4349425", "title": "Excitability changes during the sleep cycle in the cat.", "content": "Excitability changes during the sleep cycle in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349425"}
{"pmid": "4349426", "title": "A model of hippocampal CA3 circuitry.", "content": "A model of hippocampal CA3 circuitry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349426"}
{"pmid": "4349427", "title": "Synaptic inhibition in the spinal cord.", "content": "Synaptic inhibition in the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349427"}
{"pmid": "4349428", "title": "Energy and signal.", "content": "Energy and signal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349428"}
{"pmid": "4349429", "title": "Integration in the nervous system: the starch for its mechanisms.", "content": "Integration in the nervous system: the starch for its mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349429"}
{"pmid": "4349431", "title": "Statistical analysis of sleep in rats.", "content": "Statistical analysis of sleep in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349431"}
{"pmid": "4349430", "title": "Effects of the electrophoretic application of sulfhydryl reagents to the end-plate receptors.", "content": "Effects of the electrophoretic application of sulfhydryl reagents to the end-plate receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349430"}
{"pmid": "4349432", "title": "Radiologic manifestations of mongolism.", "content": "Radiologic manifestations of mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349432"}
{"pmid": "4349434", "title": "Induction of polyoma virus by fluorescent (visible) light in polyoma-transformed cells pretreated with 5-bromodeoxyuridine.", "content": "Induction of polyoma virus by fluorescent (visible) light in polyoma-transformed cells pretreated with 5-bromodeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349434"}
{"pmid": "4349435", "title": "Genetic control of the group-specific antigen of murine leukaemia virus.", "content": "Genetic control of the group-specific antigen of murine leukaemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349435"}
{"pmid": "4349436", "title": "Binding of N-acetyl-neuraminic acid by wheat-germ agglutinin.", "content": "Binding of N-acetyl-neuraminic acid by wheat-germ agglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349436"}
{"pmid": "4349437", "title": "Ribonucleoprotein binding of steroid-\"receptor\" complexes.", "content": "Ribonucleoprotein binding of steroid-\"receptor\" complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349437"}
{"pmid": "4349438", "title": "Control of phenotypic expression of cultured melanoma cells by melanocyte stimulating hormones.", "content": "Control of phenotypic expression of cultured melanoma cells by melanocyte stimulating hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349438"}
{"pmid": "4349439", "title": "Chronic stress effects on adrenocortical responsiveness in young and aged rats.", "content": "Chronic stress effects on adrenocortical responsiveness in young and aged rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349439"}
{"pmid": "4349440", "title": "Amino acids and polypeptides in neuronal function.", "content": "Amino acids and polypeptides in neuronal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349440"}
{"pmid": "4349441", "title": "Control of staphylococcal infections and disease in the newborn through the use of hexachlorophene bathing.", "content": "Control of staphylococcal infections and disease in the newborn through the use of hexachlorophene bathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349441"}
{"pmid": "4349450", "title": "Improved gel-filtration method for analysis of estrogen receptor binding.", "content": "Improved gel-filtration method for analysis of estrogen receptor binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349450"}
{"pmid": "4349452", "title": "Problems in the measurement of bile acids with 3 -hydroxysteroid dehydrogenase.", "content": "Problems in the measurement of bile acids with 3 -hydroxysteroid dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349452"}
{"pmid": "4349451", "title": "Continuous fractionation of proteins and mucopolysaccharides by simultaneous two-dimensional gel filtration and electrophoresis.", "content": "Continuous fractionation of proteins and mucopolysaccharides by simultaneous two-dimensional gel filtration and electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349451"}
{"pmid": "4349453", "title": "Separation and identification of Neurospora phosphatases by polyacrylamide gel electrophoresis.", "content": "Separation and identification of Neurospora phosphatases by polyacrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349453"}
{"pmid": "4349455", "title": "A new, sensitive method for the determination of streptomycin.", "content": "A new, sensitive method for the determination of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349455"}
{"pmid": "4349454", "title": "A simplified radiometric assay for plasma norepinephrine and epinephrine.", "content": "A simplified radiometric assay for plasma norepinephrine and epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349454"}
{"pmid": "4349459", "title": "Interference with polyoma virus replication by homologous incomplete virus.", "content": "Interference with polyoma virus replication by homologous incomplete virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349459"}
{"pmid": "4349460", "title": "Cell surface antigen on quail cells infected with herpesvirus of turkey or Marek's disease virus.", "content": "Cell surface antigen on quail cells infected with herpesvirus of turkey or Marek's disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349460"}
{"pmid": "4349461", "title": "Photo-oxidative modification of the heme ligands in horse heart ferricytochrome c: conformational and functional studies.", "content": "Photo-oxidative modification of the heme ligands in horse heart ferricytochrome c: conformational and functional studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349461"}
{"pmid": "4349462", "title": "Activation of leucocyte collagenase proenzyme by rheumatoid synovial fluid.", "content": "Activation of leucocyte collagenase proenzyme by rheumatoid synovial fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349462"}
{"pmid": "4349464", "title": "Actinomycin D for Wilm's tumour.", "content": "Actinomycin D for Wilm's tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349464"}
{"pmid": "4349463", "title": "Investigation of crosslinks in collagen following an enzymic hydrolysis.", "content": "Investigation of crosslinks in collagen following an enzymic hydrolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349463"}
{"pmid": "4349466", "title": "Studies on the replication of polyoma DNA: physicochemical properties of viral DNA synthesized when protein synthesis is inhibited.", "content": "Studies on the replication of polyoma DNA: physicochemical properties of viral DNA synthesized when protein synthesis is inhibited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349466"}
{"pmid": "4349465", "title": "Hyperlipidaemia in asthmatic patients receiving long-term steroid therapy.", "content": "Hyperlipidaemia in asthmatic patients receiving long-term steroid therapy. Plasma lipids were measured in 100 female asthmatic patients receiving long-term steroid therapy. A significant increase in the incidence of endogenous hypertriglyceridaemia but not of hypercholesterolaemia was found. The hypertriglyceridaemia was not due to obesity or diabetes. Neither the dose of steroid, duration of therapy, nor the addition of corticotrophin gel or depot tetracosactrin influenced the prevalence of hypertriglyceridaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349465"}
{"pmid": "4349468", "title": "Antigenic homogeneity of enterotoxin from different agglutinating serotypes of Clostridium perfringens.", "content": "Antigenic homogeneity of enterotoxin from different agglutinating serotypes of Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349468"}
{"pmid": "4349467", "title": "The mechanism of a host-dependent abortive bacteriophage infection in Caulobacter.", "content": "The mechanism of a host-dependent abortive bacteriophage infection in Caulobacter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349467"}
{"pmid": "4349469", "title": "A study of phagocytosis of radio-labeled Staphylococcus epidermidis and on structural events during intracellular degradation.", "content": "A study of phagocytosis of radio-labeled Staphylococcus epidermidis and on structural events during intracellular degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349469"}
{"pmid": "4349470", "title": "Degradation of poliovirus RNA in vivo.", "content": "Degradation of poliovirus RNA in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349470"}
{"pmid": "4349471", "title": "Enhancement of interferon production of murine peritoneal leukocytes by mineral oil: the effect of experimental EMC infection in mice.", "content": "Enhancement of interferon production of murine peritoneal leukocytes by mineral oil: the effect of experimental EMC infection in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349471"}
{"pmid": "4349472", "title": "Further studies on a glycolipid formed from dolichyl-D-glucosyl monophosphate.", "content": "Further studies on a glycolipid formed from dolichyl-D-glucosyl monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349472"}
{"pmid": "4349476", "title": "Stimulation of intestinal mucosal proliferation by vitamin D.", "content": "Stimulation of intestinal mucosal proliferation by vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349476"}
{"pmid": "4349477", "title": "Sexual dimorphism in hand and wrist ossification.", "content": "Sexual dimorphism in hand and wrist ossification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349477"}
{"pmid": "4349478", "title": "Hexose transport in normal and in Rous sarcoma virus-transformed cells.", "content": "Hexose transport in normal and in Rous sarcoma virus-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349478"}
{"pmid": "4349479", "title": "On the role of heme in the formation of the structure of cytochrome c.", "content": "On the role of heme in the formation of the structure of cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349479"}
{"pmid": "4349480", "title": "Evidence for an androgen-independent mechanism regulating the levels of receptor in target tissue.", "content": "Evidence for an androgen-independent mechanism regulating the levels of receptor in target tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349480"}
{"pmid": "4349482", "title": "Activation of a guanosine triphosphate-specific protein kinase by adenosine 3':5'-monophosphate-dependent protein kinase in rat cells of the rat.", "content": "Activation of a guanosine triphosphate-specific protein kinase by adenosine 3':5'-monophosphate-dependent protein kinase in rat cells of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349482"}
{"pmid": "4349481", "title": "Studies on the relationship between androgen receptors and the transport of androgens in rat prostate.", "content": "Studies on the relationship between androgen receptors and the transport of androgens in rat prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349481"}
{"pmid": "4349483", "title": "Evidence for delayed development of the glucagon receptor of adenylate cyclase in the fetal and neonatal rat heart.", "content": "Evidence for delayed development of the glucagon receptor of adenylate cyclase in the fetal and neonatal rat heart. The effects, in vivo, of epinephrine, glucagon, and dibutyryl cyclic adenosine 3',5'-monophosphate (cyclic AMP) on the glycogen content of rat heart and liver and, in vitro, upon adenylate cyclase activity in homogenates of rat heart and liver were determined during the latter third of gestation and the neonatal period. Hepatic glycogen was depleted by epinephrine, glucagon, and dibutyryl cyclic adenosine 3',5'-monophosphate, but myocardial glycogen was depleted only by epinephrine and dibutyryl cyclic AMP in the neonates. Hepatic adenylate cyclase activity was augmented by both epinephrine (10(-5) M) and glucagon (10(-5) M), and myocardial cyclase was increased only by epinephrine in tissue obtained from 16, 18, and 20 day fetal rats. Myocardial adenylate cyclase responsiveness to glucagon was present in tissue obtained from rats 4 wk of age and older. It is concluded that in contrast to hepatic adenylate cyclase, myocardial adenylate cyclase in the rat is not responsive to glucagon during gestation and that responsiveness to glucagon and the associated ability of glucagon to deplete myocardial glycogen do not develop until well after birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349483"}
{"pmid": "4349484", "title": "Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency. Further studies of very low and low density lipoprotein abnormalities.", "content": "Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency. Further studies of very low and low density lipoprotein abnormalities. Plasma lipoproteins of d<1.006 g/ml, d 1.006-1.019 g/ml, and d 1.019-1.063 g/ml from patients with familial lecithin:cholesterol acyltransferase deficiency yielded abnormal subfractions upon being separately filtered through 2% agarose gel. A subfraction that emerged with the void volume and contained unusually large amounts of unesterified cholesterol and phosphatidylcholine was present in each lipoprotein group, and in each group this subfraction was less prominent in the nonlipemic plasma of one patient than in the lipemic plasma of other patients. A subfraction containing smaller lipoproteins also was present in each lipoprotein group. These lipoproteins were of the same size as normal lipoproteins of the corresponding density, but contained abnormally small amounts of cholesteryl ester. The lipoproteins of 1.019-1.063 g/ml contained abnormal components of intermediate molecular weight as well as large and small abnormal components similar to those described previously. The intermediate components were more prominent in the nonlipemic plasma but were easily recognized in the hyperlipemic plasma as a peak of S(f) 20-30 in the analytical ultracentrifuge. Also they could be recognized, upon electron microscopy of the lipoproteins of d 1.019-1.063 g/ml, as particles 340-1000 A in diameter. The data suggest that related large, abnormal particles pervade the patients' very low and low density lipoproteins, and that the large particles are affected by, but are not dependent on, the lipemia that frequently accompanies the disease. The smaller very low and low density lipoproteins appear to be counterparts of lipoproteins present in normal plasma. Their abnormal composition is compatible with the possibility that lecithin:cholesterol acyltransferase normally decreases the triglyceride and phosphatidylcholine and increases the cholesteryl ester of very low density and low density plasma lipoproteins in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349484"}
{"pmid": "4349486", "title": "Glucagon release induced by pancreatic nerve stimulation in the dog.", "content": "Glucagon release induced by pancreatic nerve stimulation in the dog. A direct neural role in the regulation of immunoreactive glucagon (IRG) secretion has been investigated during stimulation of mixed autonomic nerves to the pancreas in anesthetized dogs. The responses were evaluated by measurement of blood flow and hormone concentration in the venous effluent from the stimulated region of pancreas. Electrical stimulation of the distal end of the discrete bundles of nerve fibers isolated along the superior pancreaticoduodenal artery was invariably followed by an increase in IRG output. With 10-min periods of nerve stimulation, the integrated response showed that the higher the control glucagon output, the greater was the increment. Atropinization did not influence the response to stimulation. That the preparation behaved in physiologic fashion was confirmed by a fall in IRG output, and a rise in immunoreactive insulin (IRI) output, during hyperglycemia induced by intravenous glucose (0.1 g/kg). The kinetics of this glucose effect on IRG showed characteristics opposite to those of nerve stimulation: the lower the control output, the less the decrement. Furthermore, during the control steady state, blood glucose concentration was tightly correlated with the IRI/IRG molar output ratio, the function relating the two parameters being markedly nonlinear. Injection or primed infusion of glucose diminished the IRG response to simultaneous nerve stimulation. Measurement of IRG was inferred to reflect response of pancreatic glucagon secretion on the basis of the site of sample collection (the superior pancreaticoduodenal vein), the absence of changes in arterial IRG, and similar responses being obtained using an antibody specific for pancreatic glucagon. THESE STUDIES SUPPORT A ROLE FOR THE AUTONOMIC NERVOUS SYSTEM IN THE CONTROL OF GLUCAGON SECRETION: direct nerve stimulation induces glucagon release. Such sympathetic activation may be interpreted as capable of shifting the sensitivity of the A cell to glucose in the direction of higher glycemia for a given glucagon output. The experimental model employed is valid for further studies of regulatory mechanisms of endocrine pancreatic function in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349486"}
{"pmid": "4349487", "title": "Study of the pedigree of a patient with type 3 hyperlipoproteinaemia and sinking prebeta lipoprotein.", "content": "Study of the pedigree of a patient with type 3 hyperlipoproteinaemia and sinking prebeta lipoprotein. A 49-year-old woman, suffering from peripheral vascular disease, was found to have two lipoprotein abnormalities, namely, type III hyperlipoproteinaemia and sinking prebeta lipoprotein. Twenty-one members of the kindred were investigated in an attempt to determine the pattern of inheritance of both of these abnormalities. In a 21-year-old son of the proband plasma electrophoresis was in keeping with a type V hyperlipoproteinaemia. It is suggested that this may be a stage in the development of the characteristic type III pattern. If this is so it is consistent with previous suggestions of an incompletely penetrant single autosomal allele. Sinking prebeta lipoprotein was found in the plasma of two other members of the family. If this abnormality is also inherited as a single autosomal allele it must have a very low penetrance and the possibility that the abnormality is acquired cannot be excluded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349487"}
{"pmid": "4349485", "title": "Specific biologic effects of intestinal glucagon-like materials.", "content": "Specific biologic effects of intestinal glucagon-like materials. It has been demonstrated that gastrointestinal extracts contain substances which react immunologically with antibodies prepared to pancreatic glucagon. These extracts have been termed intestinal GLI for glucagon-like immunoreactivity, or enteroglucagon. To determine whether GLI has specific biological effects, studies were designed using the criterion of effect with antiglucagon antibodies. These antibodies did not cross-react with either secretin or pancreozymin. Rat intestinal extracts were prepared and filtered on Sephadex G-50 columns eluted in 0.02 M ammonium carbonate buffer pH 8.8. Two peaks of GLI (I, II) were consistently found, and the in vitro effects of these peaks on two biological systems were tested: (a) immunoreactive insulin (IRI) release by rat pancreas pieces, and (b) free fatty acid (FFA) release and 3',5'-cyclic adenosine monophosphate (cAMP) levels in adipose tissue. Both GLI peaks increased IRI release in the absence of glucose and also enhanced the glucose effects. Antiglucagon antibody suppressed only peak II GLI activity. Both peaks increased FFA release and cAMP levels in adipose tissue. Only peak II GLI activity was suppressed by antibody. These findings support a specific IRI-releasing and lipolytic action for Peak II GLI. Hypotheses are presented concerning the structure and possible physiologic role of peak II GLI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349485"}
{"pmid": "4349488", "title": "Simple economical anaerobiosis.", "content": "Simple economical anaerobiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349488"}
{"pmid": "4349489", "title": "Inhibition of replication of lactic dehydrogenase virus by actinomycin.", "content": "Inhibition of replication of lactic dehydrogenase virus by actinomycin. Lactic dehydrogenase virus replicated rapidly in monolayers of primary mouse embryo cells and reached a titer of 10(8) mean infective dose per ml within 18 h after infection. Despite the high virus yield, cytopathology was not observed. Examination of the tissue culture media failed to reveal any evidence of interferon, but the virus was found to be as sensitive to mouse interferon as vesicular stomatitis virus. Incubation of mouse embryo cells with actinomycin D markedly inhibited viral replication, whereas cytosine-beta-d-arabinofuranoside and 5-fluorodeoxyuridine had no effect on replication. These findings indicate that new DNA synthesis is not required but suggest that the intact function of cellular DNA may be required for lactic dehydrogenase virus replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349489"}
{"pmid": "4349490", "title": "Initiation and direction of RNA transcription by vesicular stomatitis virus virion transcriptase.", "content": "Initiation and direction of RNA transcription by vesicular stomatitis virus virion transcriptase. The initiation of RNA transcription by the virion-bound RNA transcriptase of vesicular stomatitis virus has been examined. Multiple initiation sequences have been observed, two of which have been characterized (pppApCpGp... and pppGpCp...) suggestive of a transcription process which can start at different sites along the template RNA. By the use of sequential labeling techniques and exonucleases, it has been determined that there is a 5' to 3' direction of product RNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349490"}
{"pmid": "4349492", "title": "Surface antigens on cat leukemic cells induced by feline leukemia virus: area density and antibody-binding affinity.", "content": "Surface antigens on cat leukemic cells induced by feline leukemia virus: area density and antibody-binding affinity. The binding of autologous bovine antibody to feline leukemia virus-induced cell surface antigens (FeCSA) on cat leukemia cells was studied by performing certain titration procedures with a mixture of immune and normal sera labeled with different iodine radioisotopes (paired-label technique). By using plots of titration data which conformed to linear equations derived from the mass action law, we determined the following constants. (i) The density of FeCSA was 2.03 x 10(6) sites per cell, or 5,230 sites per mum(2). (ii) The equilibrium constant of the FeCSA-antibody reaction was 2.67 x 10(7), from which the antibody binding affinity or standard free energy of the FeCSA-antibody bond was determined to be - 10.48 kcal (-43,869.28 J) per mol. The use of the techniques described to measure the concentration of antibody in antiserum, in micrograms per milliliter, is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349492"}
{"pmid": "4349491", "title": "Analysis of simian virus 40 DNA with the restriction enzyme of Haemophilus aegyptius, endonuclease Z.", "content": "Analysis of simian virus 40 DNA with the restriction enzyme of Haemophilus aegyptius, endonuclease Z. Limited digestion of simian virus 40 (SV40) DNA from both small- and large- plaque strains with the restriction endonuclease Z from Haemophilus aegyptius yielded 10 specific fragments. The number of nucleotide pairs for each fragment, determined by co-electrophoresis with phiX174 RF fragments produced by endonuclease Z, ranges from 2,050 to 80. The difference in the pattern between the large- and small-plaque strains is the disappearance of one fragment containing approximately 255 nucleotide pairs and the appearance of a new fragment with 145 nucleotide pairs. This finding can be explained either by deletions or insertions totaling 110 nucleotide pairs. Complementary RNA synthesized in vitro from the adeno-SV40 hybrid virus, strain ND-1, hybridized preferentially to four of the fragments of SV40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349491"}
{"pmid": "4349493", "title": "Identification of the vesicular stomatitis virus large protein as a unique viral protein.", "content": "Identification of the vesicular stomatitis virus large protein as a unique viral protein. Previous studies have noted the existence of a 190,000-dalton vesicular stomatitis virus (VSV) protein called the large (L) protein. To determine whether this protein is a nonspecific aggregate, a precursor to the other VSV proteins, or a unique viral protein, its synthesis relative to the other VSV proteins was studied under conditions of inhibition of initiation of protein synthesis. Also, its tryptic peptides were compared to those of the other VSV proteins. In both cases the results were consistent with the identification of the large protein as a unique viral protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349493"}
{"pmid": "4349494", "title": "Synthesis of type 2 adenovirus DNA in the presence of cycloheximide.", "content": "Synthesis of type 2 adenovirus DNA in the presence of cycloheximide. Adenovirus type 2 DNA synthesis, either in permissive human cells or nonpermissive monkey cells, becomes independent of protein synthesis after the appearance of progeny viral DNA. In the presence of cycloheximide, semiconservative replication and initiation of progeny molecules can occur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349494"}
{"pmid": "4349496", "title": "Intracytoplasmic A particles: mouse mammary tumor virus nucleoprotein cores?", "content": "Intracytoplasmic A particles: mouse mammary tumor virus nucleoprotein cores? A rapid method for the isolation of intracytoplasmic A particles, the putative intracellular nucleoprotein cores of mouse mammary tumor virus (MTV), is presented. Spontaneous C3H/He mouse mammary tumors and transplantable mouse Leydig cell tumor were used as source material. Large aggregations of intracytoplasmic A particles were separated from cellular contaminants on discontinuous sucrose gradients and subsequently further purified by isopycnic banding in linear sucrose gradients. The purified particles were solubilized in sodium dodecyl sulfate, and the structural proteins were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Purified mouse mammary tumor virions were solubilized, and their proteins were analyzed in the same way. Comparison of co-electrophoretic gels indicated a lack of correlation in the molecular size of the major structural proteins in intracytoplasmic A particles and MTV. The three major proteins of the A particles were calculated to be 80,000; 35,000; and 20,000 daltons. Five major polyacrylamide gel electrophoresis bands were obtained with purified MTV; these were 90,000; 69,000; 55,000; 37,000; and 27,500 daltons. These figures showed good correlation with those published for MTV by Nowinski et al. These results suggest the need for the reexamination of the current tenet that intracytoplasmic particles represent intracellular MTV nucleoprotein cores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349496"}
{"pmid": "4349495", "title": "New intermediate subviral particles in the in vitro uncoating of reovirus virions by chymotrypsin.", "content": "New intermediate subviral particles in the in vitro uncoating of reovirus virions by chymotrypsin. Reovirus virions, grown in suspension cultures of L cells and extensively purified by density gradient and velocity gradient centrifugation after their release from cell debris by fluorocarbon extraction, are characterized by a mean particle diameter of 73 nm and a density in CsCl of 1.36 to 1.37 g/cm(3). Treatment of intact virions by chymotrypsin (CHT) digestion in vitro converts them to subviral particles (SVP) having characteristics which are determined by the species of monovalent cation present during the digestion. In the presence of Cs(+) ions, CHT converts the virions to SVP of mean diameter 51 nm and density 1.43 to 1.44 g/cm(3). In the presence of K(+) ions, the conversion is to SVP of diameter 51 nm and density 1.39 to 1.40 g/cm(3). The SVP made in the presence of either Cs(+) or K(+) possess an extremely active RNA polymerase and nucleoside triphosphate phosphohydrolase (NTPase) activity in vitro and are resistant to further digestion by CHT. Treatment of intact virions with CHT in the presence of Na(+) or Li(+) ions results in their conversion to SVP of mean diameter 64 nm and density 1.37 to 1.38 g/cm(3). Such SVP are not active in in vitro RNA synthesis or NTP hydrolysis and are resistant to further digestion by CHT even during prolonged exposure to high concentrations of enzyme. Addition of Cs(+) or K(+) ions to the digestion mixture allows conversion of the 64-nm diameter SVP to 51-nm diameter SVP in which the RNA polymerase and NTPase are active in vitro. Analysis of the proteins present in intact virions and in the different SVP reveals clear differences which indicate that the conversions are accomplished by removal or cleavage of particular species of polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349495"}
{"pmid": "4349498", "title": "Effect of isotopic label on buoyant density determinations of viral DNA in the preparative ultracentrifuge.", "content": "Effect of isotopic label on buoyant density determinations of viral DNA in the preparative ultracentrifuge. The buoyant density of herpes simplex virus DNA may be significantly increased by isotopic labeling, particularly with (14)C. The apparent increase in buoyant density may be readily calculated from the specific activity of the DNA and is easily demonstrated by isopycnic centrifugation in both the preparative and analytical centrifuge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349498"}
{"pmid": "4349497", "title": "Purification by oligo(dT)-cellulose of viral-specific RNA from sarcoma virus-transformed mammalian nonproducer cells.", "content": "Purification by oligo(dT)-cellulose of viral-specific RNA from sarcoma virus-transformed mammalian nonproducer cells. Viral-specific RNA has been purified by oligo(dT)-cellulose chromatography from sarcoma virus-transformed nonproducer cells. This RNA comprises approximately 3% of the purified RNA, as judged by RNA-DNA hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349497"}
{"pmid": "4349499", "title": "A genetic model of the host range restriction of murine leukemia viruses: a review and a hypothesis.", "content": "A genetic model of the host range restriction of murine leukemia viruses: a review and a hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349499"}
{"pmid": "4349500", "title": "Purification of commercially available fluorescein isothiocyanate by silicic acid column chromatography.", "content": "Purification of commercially available fluorescein isothiocyanate by silicic acid column chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349500"}
{"pmid": "4349501", "title": "Properties of a cytopathic agent isolated from a patient with subacute sclerosing panencephalitis in Japan.", "content": "Properties of a cytopathic agent isolated from a patient with subacute sclerosing panencephalitis in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349501"}
{"pmid": "4349502", "title": "Effect of dibutyryl cyclic AMP on nucleic acid and protein synthesis in neuronal and glial tumor cells.", "content": "Effect of dibutyryl cyclic AMP on nucleic acid and protein synthesis in neuronal and glial tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349502"}
{"pmid": "4349504", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 23-1973.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 23-1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349504"}
{"pmid": "4349505", "title": "Trigeminal neuralgia and herpesvirus.", "content": "Trigeminal neuralgia and herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349505"}
{"pmid": "4349506", "title": "Drug receptors and the haemopoietic stem cell.", "content": "Drug receptors and the haemopoietic stem cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349506"}
{"pmid": "4349508", "title": "Hyaluronate inhibition of chondrogenesis: antagonism of thyroxine, growth hormone, and calcitonin.", "content": "Hyaluronate inhibition of chondrogenesis: antagonism of thyroxine, growth hormone, and calcitonin. The formation of cartilage-like aggregates in high-density stationary cultures of trypsinized chick embryo precartilage cells is blocked by low concentrations of hyaluronate. Thyroxine (and triiodothyronine), growth hormone, calcitonin, and adenosine 3',5'-monophosphate prevented this inhibition by hyaluronate, whereas other hormones tested did not.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349508"}
{"pmid": "4349509", "title": "Cyclic AMP phosphodiesterase in cloned astrocytoma cells: norepinephrine induces a specific enzyme form.", "content": "Cyclic AMP phosphodiesterase in cloned astrocytoma cells: norepinephrine induces a specific enzyme form. The soluble supernatant fraction of homogenates of cloned rat astrocytoma cells (linle C-2A) was subjected to polyacrylamide gel electrophoresis. Two peaks of adenosine 3',5'-monophosphate phosphodiesterase activity were found, corresponding to peaks I and IV of a similarly prepared homogenate of rat brain. Incubating cells with norepinephrine (0.3 mullimolar) caused about a threefold increase in the activity of peak IV but no change in peak I. This increase was completely inhibited by prior inclubation with propranolol (0.1 millimnolar), a beta-adrenergic blocking agent, or with cyclohexamnine (40 micromolar). a protein synthesis inhibitor. Induction of a specific phosphodiesterase form by norepinephrine sitggests another feedback control mechanism whereby an organism can prevent the effects of excessive sympathetic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349509"}
{"pmid": "4349511", "title": "Leukemia virus activation during homograft rejection.", "content": "Leukemia virus activation during homograft rejection. Activation of murine leukemia viruses, as detected by the mixed culture cytopathogenicity (XC) assay, followed the transplantation of A/J skin onto immunosuppressed BALB/c mice. Virus was found in most of the mice receiving both skin grafts and antilymphocyte serum, but not in animals receiving either the serum alone, skin graft alone, or no treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349511"}
{"pmid": "4349510", "title": "Octopamine-sensitive adenylate cyclse: evidence for a biological role of octopamine in nervous tissue.", "content": "Octopamine-sensitive adenylate cyclse: evidence for a biological role of octopamine in nervous tissue. An adenylate cyclase that is activated specifically by very low concentrations of octopamine has been identified both in homogenates and in intact cells of the thoracic ganglia of an insect nervous system. This enzyme appears to be distinct from two other adenylate cyclases present in the same tissue, which are activated by dopamine and by 5-hydroxytryptamine, respectively. The data raise the possibility of a role of octopamine-sensitive adenylate cyclase in the physiology of synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349510"}
{"pmid": "4349512", "title": "Genetic mapping of the Fv-1 lcous of the mouse.", "content": "Genetic mapping of the Fv-1 lcous of the mouse. The Fv-l locus of the mouse, a major determinant of the biology of murine leukemia virus, is very closely linked to Gpd-1 on chromosome 4 (linkage group VIII).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349512"}
{"pmid": "4349524", "title": "Cholesterol content and phospholipid composition of Morris hepatoma microsomes.", "content": "Cholesterol content and phospholipid composition of Morris hepatoma microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349524"}
{"pmid": "4349528", "title": "Height and weight of United States children: second report.", "content": "Height and weight of United States children: second report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349528"}
{"pmid": "4349527", "title": "Gangliosidosis with total hexosaminidase deficiency: clinical, biochemical and ultrastructural studies and comparison with conventional cases of Tay-Sachs disease.", "content": "Gangliosidosis with total hexosaminidase deficiency: clinical, biochemical and ultrastructural studies and comparison with conventional cases of Tay-Sachs disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349527"}
{"pmid": "4349529", "title": "Control of vasopressin stimulation of sodium transport in the toad bladder.", "content": "Control of vasopressin stimulation of sodium transport in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349529"}
{"pmid": "4349530", "title": "Response of frog muscle spindle system to whole-muscle input parameters.", "content": "Response of frog muscle spindle system to whole-muscle input parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349530"}
{"pmid": "4349532", "title": "Effects of parathyroid hormone on renal tubular reabsorption of calcium, sodium, and phosphate.", "content": "Effects of parathyroid hormone on renal tubular reabsorption of calcium, sodium, and phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349532"}
{"pmid": "4349531", "title": "Angiotensin I conversion in the kidney and its modulation by sodium balance.", "content": "Angiotensin I conversion in the kidney and its modulation by sodium balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349531"}
{"pmid": "4349533", "title": "Extra-adrenal effect of ACTH on fibrinogen synthesis.", "content": "Extra-adrenal effect of ACTH on fibrinogen synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349533"}
{"pmid": "4349534", "title": "Influence of hypophysectomy and training on size of isolated fat cells.", "content": "Influence of hypophysectomy and training on size of isolated fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349534"}
{"pmid": "4349536", "title": "GABA-transaminase inhibitors and presynaptic inhibition in the amphibian spinal cord.", "content": "GABA-transaminase inhibitors and presynaptic inhibition in the amphibian spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349536"}
{"pmid": "4349535", "title": "Angiotensin, vasopressin, and cyclic AMP: effects on sodium and water fluxes in rat colon.", "content": "Angiotensin, vasopressin, and cyclic AMP: effects on sodium and water fluxes in rat colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349535"}
{"pmid": "4349537", "title": "Research utilization, a problem in goal setting: what is the question?", "content": "Research utilization, a problem in goal setting: what is the question?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349537"}
{"pmid": "4349538", "title": "Premorbid adjustment, paranoid diagnosis, and remission. Acute schizophrenics treated in a community mental health center.", "content": "Premorbid adjustment, paranoid diagnosis, and remission. Acute schizophrenics treated in a community mental health center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349538"}
{"pmid": "4349541", "title": "Electrical activity in neocortical projection and association areas during slow wave sleep.", "content": "Electrical activity in neocortical projection and association areas during slow wave sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349541"}
{"pmid": "4349540", "title": "Production of histamine-like and prostaglandin-like substances from serum incubated with rat, dog, mouse or human tumours.", "content": "Production of histamine-like and prostaglandin-like substances from serum incubated with rat, dog, mouse or human tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349540"}
{"pmid": "4349544", "title": "The prevention and treatment of varicella-zoster infection in patients at high risk.", "content": "The prevention and treatment of varicella-zoster infection in patients at high risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349544"}
{"pmid": "4349546", "title": "Control by TSH of a phospholipase A 2  activity, a limiting factor in the biosynthesis of prostaglandins in the thyroid.", "content": "Control by TSH of a phospholipase A 2  activity, a limiting factor in the biosynthesis of prostaglandins in the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349546"}
{"pmid": "4349547", "title": "On the subunit structure of cytochrome oxidase from beef heart mitochondria.", "content": "On the subunit structure of cytochrome oxidase from beef heart mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349547"}
{"pmid": "4349548", "title": "Hydrolysis of sphingomyelin liposomes by sphingomyelinase.", "content": "Hydrolysis of sphingomyelin liposomes by sphingomyelinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349548"}
{"pmid": "4349549", "title": "Conformational differences in the myosin-ADP complex in myofibrils and isolated myosin.", "content": "Conformational differences in the myosin-ADP complex in myofibrils and isolated myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349549"}
{"pmid": "4349550", "title": "Oxytocin receptor in frog bladder epithelial cells. Relationship of ( 3 H)oxytocin binding to adenylate cyclase activation.", "content": "Oxytocin receptor in frog bladder epithelial cells. Relationship of ( 3 H)oxytocin binding to adenylate cyclase activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349550"}
{"pmid": "4349551", "title": "On the regulatory properties of a halophilic citrate synthase.", "content": "On the regulatory properties of a halophilic citrate synthase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349551"}
{"pmid": "4349552", "title": "Ethanol-induced fatty liver: effect of intestinal lymph fistula.", "content": "Ethanol-induced fatty liver: effect of intestinal lymph fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349552"}
{"pmid": "4349553", "title": "Facial nerve preservation in relation to tumour size in acoustic nerve tumour surgery.", "content": "Facial nerve preservation in relation to tumour size in acoustic nerve tumour surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349553"}
{"pmid": "4349554", "title": "Optokinetic nystagmus in diseases of the central nervous system.", "content": "Optokinetic nystagmus in diseases of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349554"}
{"pmid": "4349555", "title": "Renal renin in experimental nephrosclerosis.", "content": "Renal renin in experimental nephrosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349555"}
{"pmid": "4349556", "title": "Causes of elevated perilymph protein concentrations.", "content": "Causes of elevated perilymph protein concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349556"}
{"pmid": "4349559", "title": "Morphological and biochemical alterations in foetal rat brain cells cultured in the presence of monobutyryl cyclic AMP.", "content": "Morphological and biochemical alterations in foetal rat brain cells cultured in the presence of monobutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349559"}
{"pmid": "4349560", "title": "Thymus and bone marrow derived lymphatic leukaemia in mice.", "content": "Thymus and bone marrow derived lymphatic leukaemia in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349560"}
{"pmid": "4349561", "title": "Cholera enterotoxin: failure of anti-inflammatory agents to prevent cyclic AMP accumulation.", "content": "Cholera enterotoxin: failure of anti-inflammatory agents to prevent cyclic AMP accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349561"}
{"pmid": "4349562", "title": "SV40 protection in myeloma oncogenesis.", "content": "SV40 protection in myeloma oncogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349562"}
{"pmid": "4349563", "title": "Transfer RNA activities of Rous sarcoma and Rous associated viruses.", "content": "Transfer RNA activities of Rous sarcoma and Rous associated viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349563"}
{"pmid": "4349564", "title": "Specificity in initiation of protein synthesis in a fractionated mammalian cell-free system.", "content": "Specificity in initiation of protein synthesis in a fractionated mammalian cell-free system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349564"}
{"pmid": "4349565", "title": "Satellite DNA replication in baby mouse kidney cells infected with polyoma virus.", "content": "Satellite DNA replication in baby mouse kidney cells infected with polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349565"}
{"pmid": "4349566", "title": "F1-histone phosphorylation in metaphase chromosomes of cultured Chinese hamster cells.", "content": "F1-histone phosphorylation in metaphase chromosomes of cultured Chinese hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349566"}
{"pmid": "4349567", "title": "Glucocorticoid binding proteins in human leukaemic lymphoblasts.", "content": "Glucocorticoid binding proteins in human leukaemic lymphoblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349567"}
{"pmid": "4349568", "title": "Periodic breathing in premature and neonatal babies: incidence, breathing pattern, respiratory gas tensions, response to changes in the composition of ambient air.", "content": "Periodic breathing in premature and neonatal babies: incidence, breathing pattern, respiratory gas tensions, response to changes in the composition of ambient air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349568"}
{"pmid": "4349569", "title": "Studies on ciliary dyskinesia factor in cystic fibrosis. II. Short term leukocyte cultures and long term lymphoid lines.", "content": "Studies on ciliary dyskinesia factor in cystic fibrosis. II. Short term leukocyte cultures and long term lymphoid lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349569"}
{"pmid": "4349570", "title": "Poly(adenosine diphosphate ribose).", "content": "Poly(adenosine diphosphate ribose).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349570"}
{"pmid": "4349584", "title": "Calcification in a gastric mucinous adenocarcinoma.", "content": "Calcification in a gastric mucinous adenocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349584"}
{"pmid": "4349586", "title": "Preparative-scale synthesis of (1R)-and (1S)-monodeuteriopropanol by enzymatic exchange reactions.", "content": "Preparative-scale synthesis of (1R)-and (1S)-monodeuteriopropanol by enzymatic exchange reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349586"}
{"pmid": "4349588", "title": "Isolation of DNA and DNA polymerase from MC 29  tumor virus.", "content": "Isolation of DNA and DNA polymerase from MC 29  tumor virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349588"}
{"pmid": "4349590", "title": "Radioisotope brain scans in the diagnosis of brain tumors: technic and applications. With emphasis on recognition of lesions outside of the posterior fossa.", "content": "Radioisotope brain scans in the diagnosis of brain tumors: technic and applications. With emphasis on recognition of lesions outside of the posterior fossa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349590"}
{"pmid": "4349595", "title": "Immunological relationship of Brucella with microorganisms of other genera.", "content": "Immunological relationship of Brucella with microorganisms of other genera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349595"}
{"pmid": "4349597", "title": "A poxvirus isolated from silvereyes (Zosterops lateralis) from Lower Hutt, New Zealand.", "content": "A poxvirus isolated from silvereyes (Zosterops lateralis) from Lower Hutt, New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349597"}
{"pmid": "4349596", "title": "The secretion of dehydroepiandrosterone and dehydroepiandrosterone sulphate in man.", "content": "The secretion of dehydroepiandrosterone and dehydroepiandrosterone sulphate in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349596"}
{"pmid": "4349598", "title": "Herpesvirus infection in the black rat (Rattus rattus).", "content": "Herpesvirus infection in the black rat (Rattus rattus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349598"}
{"pmid": "4349599", "title": "Stimulation of endogenous respiration of ejaculated ram sperm by dibutyryl cyclic AMP.", "content": "Stimulation of endogenous respiration of ejaculated ram sperm by dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349599"}
{"pmid": "4349600", "title": "Stimulation of division of density inhibited fibroblasts by glucocorticoids.", "content": "Stimulation of division of density inhibited fibroblasts by glucocorticoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349600"}
{"pmid": "4349602", "title": "Implications of chemoautotrophism in Mycobacterium leprae.", "content": "Implications of chemoautotrophism in Mycobacterium leprae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349602"}
{"pmid": "4349601", "title": "Poly (A) and poly (U) in poliovirus double stranded RNA.", "content": "Poly (A) and poly (U) in poliovirus double stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349601"}
{"pmid": "4349603", "title": "Factor in acidified serum toxic for malignant cells in culture.", "content": "Factor in acidified serum toxic for malignant cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349603"}
{"pmid": "4349605", "title": "Collagenase inhibition with penicillamine. Case report.", "content": "Collagenase inhibition with penicillamine. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349605"}
{"pmid": "4349606", "title": "Surgical decisions in the treatment of major salivary gland tumors.", "content": "Surgical decisions in the treatment of major salivary gland tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349606"}
{"pmid": "4349608", "title": "Effect of 3,7-dimethyl-1-(5-oxo-hexyl)xanthine and 1-hexyl-3,7-dimethyl xanthine on cyclic AMP phosphodiesterase of the human umbilical cord vessels.", "content": "Effect of 3,7-dimethyl-1-(5-oxo-hexyl)xanthine and 1-hexyl-3,7-dimethyl xanthine on cyclic AMP phosphodiesterase of the human umbilical cord vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349608"}
{"pmid": "4349607", "title": "Treatment of bilateral breast carcinomas in a patient with silicone-gel breast implants. Case report.", "content": "Treatment of bilateral breast carcinomas in a patient with silicone-gel breast implants. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349607"}
{"pmid": "4349609", "title": "A comparison of the effects of methyl methanesulfonate in various reproductive toxicity screening tests.", "content": "A comparison of the effects of methyl methanesulfonate in various reproductive toxicity screening tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349609"}
{"pmid": "4349611", "title": "Apparent suppression of the tumorigenicity of human cancer cells by cyclic AMP.", "content": "Apparent suppression of the tumorigenicity of human cancer cells by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349611"}
{"pmid": "4349610", "title": "Actions of lithium on cerebral carbohydrate metabolism.", "content": "Actions of lithium on cerebral carbohydrate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349610"}
{"pmid": "4349613", "title": "Retinal anlage tumour. A case report.", "content": "Retinal anlage tumour. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349613"}
{"pmid": "4349620", "title": "Genetics of hyperlipidemia in coronary heart disease.", "content": "Genetics of hyperlipidemia in coronary heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349620"}
{"pmid": "4349621", "title": "Nature of defect responsible for familial vitamin D-resistant rickets (VDRR) based on radioimmunoassay for parathyroid hormone (PTH).", "content": "Nature of defect responsible for familial vitamin D-resistant rickets (VDRR) based on radioimmunoassay for parathyroid hormone (PTH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349621"}
{"pmid": "4349622", "title": "In vitro demonstration of iodide-trapping defect but normal thyrotropin (TSH) responsiveness in benign and malignant \"cold\" thyroid nodules.", "content": "In vitro demonstration of iodide-trapping defect but normal thyrotropin (TSH) responsiveness in benign and malignant \"cold\" thyroid nodules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349622"}
{"pmid": "4349623", "title": "The syndrome of hypertension, hyperreninemia and secondary aldosteronism associated with renal juxtaglomerular cell tumor (primary reninism).", "content": "The syndrome of hypertension, hyperreninemia and secondary aldosteronism associated with renal juxtaglomerular cell tumor (primary reninism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349623"}
{"pmid": "4349624", "title": "Clinical experiences with tumours of the lacrimal gland.", "content": "Clinical experiences with tumours of the lacrimal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349624"}
{"pmid": "4349625", "title": "Pathology of some lacrimal gland tumours.", "content": "Pathology of some lacrimal gland tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349625"}
{"pmid": "4349626", "title": "Studies on biosynthesis of polymyxin E (colistin). II. Biosynthesis of polymyxin E by mutants m-5 and d-13 of Bacillus polymyxa K-1.", "content": "Studies on biosynthesis of polymyxin E (colistin). II. Biosynthesis of polymyxin E by mutants m-5 and d-13 of Bacillus polymyxa K-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349626"}
{"pmid": "4349627", "title": "A new approach to hyperlipoproteinemia phenotyping.", "content": "A new approach to hyperlipoproteinemia phenotyping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349627"}
{"pmid": "4349629", "title": "Experimental herpes simplex encephalitis. Treatment with pyrimidine nucleosides.", "content": "Experimental herpes simplex encephalitis. Treatment with pyrimidine nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349629"}
{"pmid": "4349628", "title": "Clarification of some basic vocabulary: terminology today.", "content": "Clarification of some basic vocabulary: terminology today.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349628"}
{"pmid": "4349630", "title": "Motor nerve terminal and muscle membrane stabilization by diphenylhydantoin administration.", "content": "Motor nerve terminal and muscle membrane stabilization by diphenylhydantoin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349630"}
{"pmid": "4349631", "title": "Cerebral arterial spasm. Modification by inhibition of platelet function.", "content": "Cerebral arterial spasm. Modification by inhibition of platelet function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349631"}
{"pmid": "4349632", "title": "Herpetic meningitis (type 1) in a case of acute leukemia.", "content": "Herpetic meningitis (type 1) in a case of acute leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349632"}
{"pmid": "4349633", "title": "Spinal ganglion in herpes zoster. A light and electron microscopic study.", "content": "Spinal ganglion in herpes zoster. A light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349633"}
{"pmid": "4349634", "title": "Genetics and colon cancer.", "content": "Genetics and colon cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349634"}
{"pmid": "4349642", "title": "The glycosaminoglycans of articular cartilage in calcium pyrophosphate dihydrate (CPPD) crystal deposition disease (chondrocalcinosis articularis or pyrophosphate arthropathy).", "content": "The glycosaminoglycans of articular cartilage in calcium pyrophosphate dihydrate (CPPD) crystal deposition disease (chondrocalcinosis articularis or pyrophosphate arthropathy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349642"}
{"pmid": "4349643", "title": "Subcellular fractionation of the enterocyte with special reference to peptide hydrolases.", "content": "Subcellular fractionation of the enterocyte with special reference to peptide hydrolases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349643"}
{"pmid": "4349644", "title": "Comparison of steroidogenic effects of cAMP and dbcAMP in the rat adrenal gland.", "content": "Comparison of steroidogenic effects of cAMP and dbcAMP in the rat adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349644"}
{"pmid": "4349645", "title": "Evidence for a role of adenosine 3',5'-monophosphate in parathyroid hormone release.", "content": "Evidence for a role of adenosine 3',5'-monophosphate in parathyroid hormone release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349645"}
{"pmid": "4349646", "title": "Cyclic 3'5'-adenosine monophosphate in isolated bone cells. Response to low concentrations of parathyroid hormone.", "content": "Cyclic 3'5'-adenosine monophosphate in isolated bone cells. Response to low concentrations of parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349646"}
{"pmid": "4349647", "title": "On the mechanism of action of luteinizing hormone-releasing factor and prolactin release inhibiting factor.", "content": "On the mechanism of action of luteinizing hormone-releasing factor and prolactin release inhibiting factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349647"}
{"pmid": "4349648", "title": "Regional responses of the pituitary to corticotropin-releasing factor (CRF) and ammonium ions.", "content": "Regional responses of the pituitary to corticotropin-releasing factor (CRF) and ammonium ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349648"}
{"pmid": "4349649", "title": "Biologic action of 1,25-dihydroxy-vitamin D3 in the rachitic dog.", "content": "Biologic action of 1,25-dihydroxy-vitamin D3 in the rachitic dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349649"}
{"pmid": "4349650", "title": "Effects of some modifiers of insulin secretion on insulin biosynthesis.", "content": "Effects of some modifiers of insulin secretion on insulin biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349650"}
{"pmid": "4349651", "title": "Effects of calcium and theophylline on ACTH- and dibutyryl cyclic AMP-stimulated steroidogenesis and glycolysis by intact mouse adrenal glands in vitro.", "content": "Effects of calcium and theophylline on ACTH- and dibutyryl cyclic AMP-stimulated steroidogenesis and glycolysis by intact mouse adrenal glands in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349651"}
{"pmid": "4349652", "title": "Luteinization of transplanted ovarian follicles in the rat induced by dibutyryl cyclic AMP.", "content": "Luteinization of transplanted ovarian follicles in the rat induced by dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349652"}
{"pmid": "4349653", "title": "Lack of specificity for the extra-ovarian prolactin effect on vaginal mucification in rats.", "content": "Lack of specificity for the extra-ovarian prolactin effect on vaginal mucification in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349653"}
{"pmid": "4349654", "title": "The subunit structure of rabbit-skeletal-muscle phosphorylase kinase, and the molecular basis of its activation reactions.", "content": "The subunit structure of rabbit-skeletal-muscle phosphorylase kinase, and the molecular basis of its activation reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349654"}
{"pmid": "4349655", "title": "Luminescence quenching in azurin.", "content": "Luminescence quenching in azurin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349655"}
{"pmid": "4349656", "title": "Spin-labelled phosphofructokinase and its interactions with ATP and metal-ATP complexes as studied by magnetic-resonance methods.", "content": "Spin-labelled phosphofructokinase and its interactions with ATP and metal-ATP complexes as studied by magnetic-resonance methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349656"}
{"pmid": "4349657", "title": "Transport of lactate and succinate by membrane vesicles of Escherichia coli, Bacillus subtilis and a pseudomonas species.", "content": "Transport of lactate and succinate by membrane vesicles of Escherichia coli, Bacillus subtilis and a pseudomonas species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349657"}
{"pmid": "4349658", "title": "Diacetyl (acetoin) reductase from Aerobacter aerogenes. Kinetic studies of the reduction of diacetyl to acetoin.", "content": "Diacetyl (acetoin) reductase from Aerobacter aerogenes. Kinetic studies of the reduction of diacetyl to acetoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349658"}
{"pmid": "4349660", "title": "Isolation of viruses, bacteria and other organisms from venereal disease clinic patients: methodology and problems associated with multiple isolations.", "content": "Isolation of viruses, bacteria and other organisms from venereal disease clinic patients: methodology and problems associated with multiple isolations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349660"}
{"pmid": "4349661", "title": "Serum lipoproteins of normal and cholesterol-fed rats.", "content": "Serum lipoproteins of normal and cholesterol-fed rats. The density distribution of lipoproteins in rats fed chow or chow containing 1% cholesterol and 10% olive oil was studied. Lipoprotein fractions were prepared in the ultra-centrifuge between narrow density bands within the density range of 1.006-1.21 and were analyzed by chemical, electrophoretic, and immunological methods. In serum from normal rats there were three major lipoprotein fractions, with densities less than 1.006, 1.030-1.063, and 1.063-1.21. Almost no lipoprotein was found between d 1.006 and 1.030. Most of the low density lipoprotein appeared between a density of 1.04 and 1.05. In the density range 1.05-1.07, small amounts of both low density and high density lipoprotein were found. Feeding a diet high in cholesterol resulted in a marked increase in the concentration of lipoproteins of density less than 1.006, and a new lipoprotein fraction appeared between d 1.006 and 1.030; this fraction contained immunologically demonstrable low density and high density lipoproteins. In addition, there was a decrease in the high density lipoprotein fraction between d 1.070 and 1.21.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349661"}
{"pmid": "4349662", "title": "Early changes in plasma lipoprotein structure and biosynthesis in cholesterol-fed rabbits.", "content": "Early changes in plasma lipoprotein structure and biosynthesis in cholesterol-fed rabbits. Plasma lipoproteins of d < 1.063 g/ml from rabbits fed a diet containing 1% cholesterol for 4 days showed changes in concentration and rates of flotation as determined by analytical ultracentrifugation. A marked increase in cholesteryl ester content of lipoprotein with d < 1.019 g/ml was the most prominent change in rabbits fed the diet for 21 days. Gel electrophoresis and immunochemical procedures demonstrated that in control and hypercholesterolemic rabbits there were some common apolipoproteins found in all lipoproteins with density < 1.063 g/ml. In control rabbits, there were also apolipoproteins specific to the lipoprotein fraction with d < 1.019 and to the fraction with d 1.019-1.063 g/ml. However, in rabbits fed the hypercholesterolemic diet for 21 days, the apolipoproteins characteristic of fraction 1.019-1.063 were the most abundant in the fraction with d < 1.019 g/ml. Liver slices from rabbits fed the high cholesterol diet for 7 and 21 days incorporated more l-[(14)C]leucine into very low density and low density lipoproteins than controls. The results suggest that cholesterol feeding leads to an increase in biosynthesis of lipoproteins with d < 1.063 g/ml. The newly synthesized lipoprotein contains apolipoproteins similar to those found in controls but with a higher lipid-to-protein ratio. From the apoprotein composition, it is concluded that the very low density fraction present in cholesterol-fed animals is more structurally related to low density lipoproteins than to the very low density lipoproteins isolated from control animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349662"}
{"pmid": "4349664", "title": "Identification of mountebank healing artists.", "content": "Identification of mountebank healing artists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349664"}
{"pmid": "4349663", "title": "Effects of ethanol on the metabolism of free fatty acids in isolated liver cells.", "content": "Effects of ethanol on the metabolism of free fatty acids in isolated liver cells. Ethanol inhibited the oxidation and enhanced the esterification of albumin-bound [1-(14)C]palmitate incubated with isolated rat liver cells. Ethanol decreased the conversion of [1-(14)C]palmitate to (14)CO(2) and (14)C-labeled ketone bodies and enhanced the incorporation of [1-(14)C]palmitate into glycerolipids, especially triglyceride; cholesteryl ester synthesis was unaffected. The half-maximal effective ethanol concentration for each of these processes was 6-10 micro g/ml and a maximum effect was produced by about 50 micro g/ml. Ethanol oxidation was required for each of these alterations, since the effects were completely abolished by pyrazole. The energy obtainable from ethanol oxidation was in excess of the energy deficit from decreased fatty acid oxidation. However, ethanol did not affect O(2) consumption, indicating that ethanol oxidation replaced the oxidation of both fatty acids and other substrates. Ethanol inhibited the citric acid cycle in the intact liver cells by 20-30%. The major site of inhibition was alpha-ketoglutarate oxidation. Results suggest that ethanol inhibited alpha-ketoglutarate dehydrogenase in the mitochondria of hepatocytes by elevating the mitochondrial NADH:NAD ratio. A minor site of inhibition of ethanol oxidation was detected between succinate and citrate. It is suggested that ethanol inhibits fatty acid oxidation in hepatocytes by competitive substrate oxidation, resulting in an increased availability of long-chain free fatty acids; this thereby enhances esterification, leading to accumulation of liver triglyceride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349663"}
{"pmid": "4349666", "title": "Human tumours grown in mice.", "content": "Human tumours grown in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349666"}
{"pmid": "4349668", "title": "Forssman reactivity and cell contacts in cultured hamster cells.", "content": "Forssman reactivity and cell contacts in cultured hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349668"}
{"pmid": "4349667", "title": "Effects of cytochrome c on liver functions of old rats.", "content": "Effects of cytochrome c on liver functions of old rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349667"}
{"pmid": "4349669", "title": "Polymorphism of natural DNA.", "content": "Polymorphism of natural DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349669"}
{"pmid": "4349670", "title": "Regulation of phospho-enol-pyruvate carboxykinase during starvation and glucose repression.", "content": "Regulation of phospho-enol-pyruvate carboxykinase during starvation and glucose repression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349670"}
{"pmid": "4349671", "title": "Inhibition of adenovirus type 12 induced DNA synthesis in G1-arrested BHK21 cells by dibutyryl adenosine cyclic 3':5'-monophosphate.", "content": "Inhibition of adenovirus type 12 induced DNA synthesis in G1-arrested BHK21 cells by dibutyryl adenosine cyclic 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349671"}
{"pmid": "4349672", "title": "Growth control and cyclic alterations of cyclic AMP in the cell cycle.", "content": "Growth control and cyclic alterations of cyclic AMP in the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349672"}
{"pmid": "4349673", "title": "Cell line derived from Balb-3T3 that is transformed by murine leukaemia virus: a focus assay for leukaemia virus.", "content": "Cell line derived from Balb-3T3 that is transformed by murine leukaemia virus: a focus assay for leukaemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349673"}
{"pmid": "4349674", "title": "Inhibition of MLV-induced transformation in Balb-3T3 derived cells.", "content": "Inhibition of MLV-induced transformation in Balb-3T3 derived cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349674"}
{"pmid": "4349675", "title": "Sub-clinical involvement of peripheral nerves in Hodgkin's disease.", "content": "Sub-clinical involvement of peripheral nerves in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349675"}
{"pmid": "4349676", "title": "The incidence and significance of Australia antigen in cancer patients.", "content": "The incidence and significance of Australia antigen in cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349676"}
{"pmid": "4349677", "title": "Stimulation and retardation of limb regeneration by adenosine 3',5'-monophosphate and related compounds.", "content": "Stimulation and retardation of limb regeneration by adenosine 3',5'-monophosphate and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349677"}
{"pmid": "4349678", "title": "The neurophysiologic basis of pain.", "content": "The neurophysiologic basis of pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349678"}
{"pmid": "4349679", "title": "Fundamental considerations of chronic pain therapy.", "content": "Fundamental considerations of chronic pain therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349679"}
{"pmid": "4349690", "title": "Chemodectomas of the head and neck.", "content": "Chemodectomas of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349690"}
{"pmid": "4349691", "title": "Cytomegalic inclusion disease. Report of a case diagnosed radiologically.", "content": "Cytomegalic inclusion disease. Report of a case diagnosed radiologically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349691"}
{"pmid": "4349692", "title": "The Tecumseh study of respiratory illness. V. Patterns of infection with the parainfluenzaviruses.", "content": "The Tecumseh study of respiratory illness. V. Patterns of infection with the parainfluenzaviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349692"}
{"pmid": "4349693", "title": "The epidemiology of hepatitis B antigen in a high prevalence area.", "content": "The epidemiology of hepatitis B antigen in a high prevalence area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349693"}
{"pmid": "4349694", "title": "A seroepidemiological study of Epstein-Barr virus and other viral antigens in sarcoidosis.", "content": "A seroepidemiological study of Epstein-Barr virus and other viral antigens in sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349694"}
{"pmid": "4349695", "title": "Stimulation of granulation tissue growth in burns.", "content": "Stimulation of granulation tissue growth in burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349695"}
{"pmid": "4349700", "title": "A mathematical evaluation of tumour growth curves in rapid, intermediate and slow growing rat hepatomata.", "content": "A mathematical evaluation of tumour growth curves in rapid, intermediate and slow growing rat hepatomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349700"}
{"pmid": "4349706", "title": "Conformational and biological properties of partial sequences of glucagon.", "content": "Conformational and biological properties of partial sequences of glucagon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349706"}
{"pmid": "4349707", "title": "Expectancy and the pituitary-adrenal system.", "content": "Expectancy and the pituitary-adrenal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349707"}
{"pmid": "4349708", "title": "Coexistent herpes simplex encephalitis and malignant astrocytoma. A clinicopathologic study of three cases.", "content": "Coexistent herpes simplex encephalitis and malignant astrocytoma. A clinicopathologic study of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349708"}
{"pmid": "4349709", "title": "Immunoglobulins and EB virus antibodies in infectious mononucleosis.", "content": "Immunoglobulins and EB virus antibodies in infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349709"}
{"pmid": "4349710", "title": "Serum autoantibodies in hepatitis associated antigen (HAA) positive patients. A possible index of cell-mediated immunity to the associated-infective agent.", "content": "Serum autoantibodies in hepatitis associated antigen (HAA) positive patients. A possible index of cell-mediated immunity to the associated-infective agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349710"}
{"pmid": "4349711", "title": "Intracellular IgA immunoglobulin crystals in chronic lymphocytic leukaemia.", "content": "Intracellular IgA immunoglobulin crystals in chronic lymphocytic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349711"}
{"pmid": "4349712", "title": "Enzymic degradation of cartilage in osteoarthritis.", "content": "Enzymic degradation of cartilage in osteoarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349712"}
{"pmid": "4349715", "title": "Selective media in the isolation of tubercle bacilli from tissues.", "content": "Selective media in the isolation of tubercle bacilli from tissues. Direct culture on Lowenstein-Jensen slopes and on three media made selective for tubercle bacilli by the addition of four antibacterial agents was compared with guinea-pig inoculation on 490 tissue specimens. Tubercle bacilli were obtained from 15 specimens by culture and 14 by guinea-pig inoculation; only one specimen was positive by guinea-pig and not by culture. The most efficient culture medium was a selective 7H11 slope. Routine guinea-pig inoculation has been replaced by a wider range of culture procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349715"}
{"pmid": "4349714", "title": "A comparative study of five laboratory tests for foeto-placental dysfunction in late pregnancy.", "content": "A comparative study of five laboratory tests for foeto-placental dysfunction in late pregnancy. Five foeto-placental function tests were studied in parallel in normal and abnormal late pregnancies with a view to establishing which test or tests is most satisfactorily able to identify the mother whose foetus is in danger.A critical examination of the levels in blood serum of two enzymes, placental phosphatase isoenzyme and cystine aminopeptidase, the polypeptide hormone placental lactogen (chorionic somatomammotrophin), and the oestrogen oestriol-17beta is described.A correlation was attempted beween clinical data and the results of the above laboratory analyses and also with the daily urine oestrogen output. The plasma and urine oestriol levels proved generally to be the more useful warning tests in late pregnancy, whilst the plasma cystine aminopeptidase was the least sensitive indicator of foeto-placental dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349714"}
{"pmid": "4349716", "title": "Distribution of  14 C-isoxazole in adrenals, ovaries, and breast carcinoma.", "content": "Distribution of  14 C-isoxazole in adrenals, ovaries, and breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349716"}
{"pmid": "4349717", "title": "Caval-portal shunting as a cause of a focal increase in radiocolloid uptake in normal livers.", "content": "Caval-portal shunting as a cause of a focal increase in radiocolloid uptake in normal livers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349717"}
{"pmid": "4349718", "title": "Localization of  99m Tc in the choroid plexus of the fourth ventricle.", "content": "Localization of  99m Tc in the choroid plexus of the fourth ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349718"}
{"pmid": "4349720", "title": "Evidence for naturally occurring murine sarcoma virus.", "content": "Evidence for naturally occurring murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349720"}
{"pmid": "4349721", "title": "Puromycin stimulation of rat liver ornithine decarboxylase activity.", "content": "Puromycin stimulation of rat liver ornithine decarboxylase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349721"}
{"pmid": "4349719", "title": "Concentration of selected intravenously administered antibiotics in experimental surgical wounds.", "content": "Concentration of selected intravenously administered antibiotics in experimental surgical wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349719"}
{"pmid": "4349722", "title": "Prostaglandin E2: effects on aggregation, shape change and cyclic AMP of rat platelets.", "content": "Prostaglandin E2: effects on aggregation, shape change and cyclic AMP of rat platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349722"}
{"pmid": "4349723", "title": "Effects of a prostaglandin antagonist, polyphloretin phosphate, on basal and stimulated thyroid function.", "content": "Effects of a prostaglandin antagonist, polyphloretin phosphate, on basal and stimulated thyroid function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349723"}
{"pmid": "4349724", "title": "Properties of 15-hydroxy prostaglandin dehydrogenase: structural requirements for substrate binding.", "content": "Properties of 15-hydroxy prostaglandin dehydrogenase: structural requirements for substrate binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349724"}
{"pmid": "4349725", "title": "Reversibility of 15-OH prostaglandin dehydrogenase from swine lung.", "content": "Reversibility of 15-OH prostaglandin dehydrogenase from swine lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349725"}
{"pmid": "4349726", "title": "Radioimmunoassay of prostaglandins, angiotensin, digoxin, morphine and adenosine-3',5'-cyclic-monophosphate with nitrocellulose membranes.", "content": "Radioimmunoassay of prostaglandins, angiotensin, digoxin, morphine and adenosine-3',5'-cyclic-monophosphate with nitrocellulose membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349726"}
{"pmid": "4349727", "title": "Resection of the inferior vena cava for adjacent malignant diseases.", "content": "Resection of the inferior vena cava for adjacent malignant diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349727"}
{"pmid": "4349728", "title": "Pitfalls of local excision in the treatment of carcinoma of the breast.", "content": "Pitfalls of local excision in the treatment of carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349728"}
{"pmid": "4349729", "title": "Long term survivors after resection of bronchial carcinoma.", "content": "Long term survivors after resection of bronchial carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349729"}
{"pmid": "4349730", "title": "Summary of recent abstracts. II. Amoebiasis and intestinal protozoal infections.", "content": "Summary of recent abstracts. II. Amoebiasis and intestinal protozoal infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349730"}
{"pmid": "4349737", "title": "A therapeutic aftercare setting for \"refractory\" chronic schizophrenic patients.", "content": "A therapeutic aftercare setting for \"refractory\" chronic schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349737"}
{"pmid": "4349738", "title": "Proteoglycans-collagen interactions in human costal cartilage.", "content": "Proteoglycans-collagen interactions in human costal cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349738"}
{"pmid": "4349739", "title": "Primary structure of cytochrome c from the emu, Dromaeus novaehollandiae.", "content": "Primary structure of cytochrome c from the emu, Dromaeus novaehollandiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349739"}
{"pmid": "4349741", "title": "Cyclic adenosine monophosphate and cardiac contractility.", "content": "Cyclic adenosine monophosphate and cardiac contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349741"}
{"pmid": "4349743", "title": "Isolation and identification of phospholipids from root tip cell plasmalemma of Phaseolus limensis.", "content": "Isolation and identification of phospholipids from root tip cell plasmalemma of Phaseolus limensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349743"}
{"pmid": "4349742", "title": "Substrate requirements for angiotensin I conversion in vivo and in vitro.", "content": "Substrate requirements for angiotensin I conversion in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349742"}
{"pmid": "4349744", "title": "Comparative studies on the effects of aminoglutethimide, metopirone, ACTH and hydrocortisone on the adrenal cortex of adult male rats. II. Histological and histochemical studies.", "content": "Comparative studies on the effects of aminoglutethimide, metopirone, ACTH and hydrocortisone on the adrenal cortex of adult male rats. II. Histological and histochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349744"}
{"pmid": "4349747", "title": "Effect of angiotensin on water and electrolyte excretion in normal and cirrhotic rats.", "content": "Effect of angiotensin on water and electrolyte excretion in normal and cirrhotic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349747"}
{"pmid": "4349748", "title": "Histochemical alterations in tissue culture produced by enteroviruses.", "content": "Histochemical alterations in tissue culture produced by enteroviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349748"}
{"pmid": "4349749", "title": "Cytomegalovirus infection of two neonates with evidence of lympho-proliferation.", "content": "Cytomegalovirus infection of two neonates with evidence of lympho-proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349749"}
{"pmid": "4349750", "title": "Inhibition of macrophage migration by a proteoglycan extracted from Kurloff cells of the guinea-pig.", "content": "Inhibition of macrophage migration by a proteoglycan extracted from Kurloff cells of the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349750"}
{"pmid": "4349751", "title": "Virus-induced diabetes mellitus. I. Hyperglycemia and hypoinsulinemia in mice infected with encephalomyocarditis virus.", "content": "Virus-induced diabetes mellitus. I. Hyperglycemia and hypoinsulinemia in mice infected with encephalomyocarditis virus. Infection of DBA/2N male mice with encephalomyocarditis virus resulted in a diabeteslike syndrome characterized by hyperglycemia, glycosuria, hypoinsulinemia, polydipsia, and polyphagia. Blood glucose levels were elevated within 4 days after infection and reached a maximum mean level of 320 mg/100 ml within 12 days. Approximately 60-80% of the animals developed a transient hyperglycemia while 10-15% of the animals remained hyperglycemic for well over 6 mo. The remaining animals failed to become hyperglycemic but many had abnormal glucose tolerance curves. Hyperglycemia was most pronounced when animals were allowed free access to food, and the incidence of byperglycemia was related both to the strain and sex of the animals, with few females developing hyperglycemia. The amount of immunoreactive insulin in the plasma of infected hyperglycemic mice was significantly lower than in appropriate controls, and injection of exogenous insulin resulted in a rapid drop in the blood glucose levels. Despite the fact that certain animals were hyperglycemic for many months, virus could not be recovered from the pancreas after the first 10 days of the infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349751"}
{"pmid": "4349756", "title": "Studies on polynucleotides. CXVI. A further study of the T4 ligase-catalyzed joining of DNA at base-paired ends.", "content": "Studies on polynucleotides. CXVI. A further study of the T4 ligase-catalyzed joining of DNA at base-paired ends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349756"}
{"pmid": "4349752", "title": "The influence of the partner cell on the production of L virus and the expression of viral surface antigen in hybrid cells.", "content": "The influence of the partner cell on the production of L virus and the expression of viral surface antigen in hybrid cells. The C-type particles produced by the A9 and A9HT sublines of mouse L cells were shown to infect C3H (N type), but not C57BL (B type), mouse embryo fibroblasts. Infection was indicated by distinct single giant cell formation in the XC monolayer used to overlay the mouse embryo fibroblasts. On the basis of these results it was concluded that the L cell virus is N tropic. A9 and A9HT cells were fused to various mouse cells derived from tumors and normal tissues. The ability to produce the Moloney-type surface antigen and to release infectious virus was introduced by the A9 component into the hybrid cell. Virus production, measured by antigen induction on JLS-V9 cells, was suppressed in those hybrids in which the partner cell had a genotype determining low infectibility with that particular virus (B-type cell). It thus appears that the major genetic locus affecting resistance to infection with leukemia viruses, the Fv-1 locus, regulates infectious virus production in somatic cell hybrids also. The same genetic locus did not seem to govern the expression of all virus-related functions, for the virus-determined membrane antigen was demonstrated in many of the N x B-type hybrids in which production of infectious virus was suppressed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349752"}
{"pmid": "4349757", "title": "Replication of polyoma DNA in isolated nuclei. I. Characterization of the system from mouse fibroblast 3T6 cells.", "content": "Replication of polyoma DNA in isolated nuclei. I. Characterization of the system from mouse fibroblast 3T6 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349757"}
{"pmid": "4349758", "title": "Replication of polyoma DNA in isolated nuclei. II. Evidence for semi-conservative replication.", "content": "Replication of polyoma DNA in isolated nuclei. II. Evidence for semi-conservative replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349758"}
{"pmid": "4349759", "title": "Polypeptide conformation of cytoplasmic malate dehydrogenase from an electron density map at 3.0 angstrom resolution.", "content": "Polypeptide conformation of cytoplasmic malate dehydrogenase from an electron density map at 3.0 angstrom resolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349759"}
{"pmid": "4349760", "title": "Regulation of skeletal muscle contraction. II. Structural studies of the interaction of the tropomyosin-troponin complex with actin.", "content": "Regulation of skeletal muscle contraction. II. Structural studies of the interaction of the tropomyosin-troponin complex with actin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349760"}
{"pmid": "4349761", "title": "Isolation and some distinctive properties of a new type of recombination-deficient mutant of Bacillus subtilis.", "content": "Isolation and some distinctive properties of a new type of recombination-deficient mutant of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349761"}
{"pmid": "4349762", "title": "Antigen expression and colony formation of lymphoblastoid cell lines after superinfection with Epstein-Barr virus.", "content": "Antigen expression and colony formation of lymphoblastoid cell lines after superinfection with Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349762"}
{"pmid": "4349763", "title": "DNA polymerase activity and DNA synthesis in preneoplastic nodule outgrowths of BALB-c and C3H mouse mammary gland.", "content": "DNA polymerase activity and DNA synthesis in preneoplastic nodule outgrowths of BALB-c and C3H mouse mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349763"}
{"pmid": "4349764", "title": "Production and characterization of human cell-adapted murine Rauscher virus pseudotype of murine sarcoma virus.", "content": "Production and characterization of human cell-adapted murine Rauscher virus pseudotype of murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349764"}
{"pmid": "4349765", "title": "Induction of bladder cancer in hamsters by repeated intratracheal administrations of 2-acetylaminofluorene.", "content": "Induction of bladder cancer in hamsters by repeated intratracheal administrations of 2-acetylaminofluorene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349765"}
{"pmid": "4349766", "title": "Comparative studies on Visna, progressive pneumonia, and Rous sarcoma viruses by electron microscopy.", "content": "Comparative studies on Visna, progressive pneumonia, and Rous sarcoma viruses by electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349766"}
{"pmid": "4349767", "title": "Occurrence of a primary liver carcinoma in a Rhesus monkey fed aflatoxin B 1 .", "content": "Occurrence of a primary liver carcinoma in a Rhesus monkey fed aflatoxin B 1 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349767"}
{"pmid": "4349769", "title": "Release of mouse leukemia-sarcoma virus from synchronized cells.", "content": "Release of mouse leukemia-sarcoma virus from synchronized cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349769"}
{"pmid": "4349768", "title": "Cyclic adenosine 3',5'-monophosphate in the control of melanoma cell replication and differentiation.", "content": "Cyclic adenosine 3',5'-monophosphate in the control of melanoma cell replication and differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349768"}
{"pmid": "4349771", "title": "Malignant, non-functional, non-chromaffin paraganglioma of the retroperitoneum.", "content": "Malignant, non-functional, non-chromaffin paraganglioma of the retroperitoneum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349771"}
{"pmid": "4349770", "title": "Hepatoma with unusual associations.", "content": "Hepatoma with unusual associations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349770"}
{"pmid": "4349773", "title": "Phospholipids of marine origin. VI. The octopus (Octopus vulgaris).", "content": "Phospholipids of marine origin. VI. The octopus (Octopus vulgaris).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349773"}
{"pmid": "4349772", "title": "The action of calcium at spinal neurones of the frog.", "content": "The action of calcium at spinal neurones of the frog. 1. The action of Ca on membrane excitability and synaptic transmission at motoneurones of the isolated spinal cord of the frog has been studied.2. Impulse propagation along presynaptic fibres was unaffected by [Ca] in the range of 0-10 mM in the presence of 1 mM-Mg.3. Motoneurone membrane excitability was within normal ranges when the cord was bathed in low or 0 Ca solutions containing 1 mM-Mg but was depressed in 5 or 10 mM-Ca solutions.4. Spontaneous miniature synaptic potentials were recorded in the presence of tetrodotoxin. The frequencies were reduced but not abolished in the absence of bath Ca, but were increased greater than twofold in 5 or 10 mM-Ca in comparison to those in normal Ringer solution (1 mM-Ca).5. Iontophoretic application of Ca both near to and remotely from the intracellular recording site (presumably in the soma) caused facilitation of elicited post-synaptic potentials.6. It is concluded that the action of Ca at these central synapses is identical to that described at the neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349772"}
{"pmid": "4349775", "title": "Synthesis of the arabinose operon regulator protein in a cell-free system.", "content": "Synthesis of the arabinose operon regulator protein in a cell-free system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349775"}
{"pmid": "4349776", "title": "Superinfection with Epstein-Barr virus of human lymphoid cell lines of different origin.", "content": "Superinfection with Epstein-Barr virus of human lymphoid cell lines of different origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349776"}
{"pmid": "4349777", "title": "Foetal liver tRNA phe  in rat hepatoma.", "content": "Foetal liver tRNA phe  in rat hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349777"}
{"pmid": "4349778", "title": "Extraction of soluble gonadotrophin receptors from rat testis.", "content": "Extraction of soluble gonadotrophin receptors from rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349778"}
{"pmid": "4349779", "title": "Androgen \"receptor\" in rat liver: cytosol \"receptor\" deficiency in pseudohermaphrodite male rats.", "content": "Androgen \"receptor\" in rat liver: cytosol \"receptor\" deficiency in pseudohermaphrodite male rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349779"}
{"pmid": "4349781", "title": "Chlorophyll interactions and light conversion in photosynthesis.", "content": "Chlorophyll interactions and light conversion in photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349781"}
{"pmid": "4349780", "title": "Dopamine: excitatory and inhibitory transmission from a giant dopamine neurone.", "content": "Dopamine: excitatory and inhibitory transmission from a giant dopamine neurone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349780"}
{"pmid": "4349783", "title": "Effect of human calcitonin on the sarcoplasmic reticulum of the human heart.", "content": "Effect of human calcitonin on the sarcoplasmic reticulum of the human heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349783"}
{"pmid": "4349782", "title": "In vivo binding of tritiated actinomycin to cellular chromatin.", "content": "In vivo binding of tritiated actinomycin to cellular chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349782"}
{"pmid": "4349784", "title": "Recovery of cerebral energy metabolism after complete ischemia of one hour's duration.", "content": "Recovery of cerebral energy metabolism after complete ischemia of one hour's duration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349784"}
{"pmid": "4349785", "title": "Carcinogenicity of  -hydroxylated dipropylnitrosamine.", "content": "Carcinogenicity of  -hydroxylated dipropylnitrosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349785"}
{"pmid": "4349786", "title": "Calcium transport and mobilization mediated by 1,25-dihydroxycholecalciferol.", "content": "Calcium transport and mobilization mediated by 1,25-dihydroxycholecalciferol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349786"}
{"pmid": "4349795", "title": "Oxidation of formate and oxalate in peroxisomal preparations from leaves of spinach beet (Beta vulgaris L.).", "content": "Oxidation of formate and oxalate in peroxisomal preparations from leaves of spinach beet (Beta vulgaris L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349795"}
{"pmid": "4349796", "title": "Cyclic AMP-dependent diphosphoinositide kinase.", "content": "Cyclic AMP-dependent diphosphoinositide kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349796"}
{"pmid": "4349797", "title": "Cyclic AMP levels in various tissues of the domestic fowl (Gallus domesticus) as affected by glucagon, epinephrine and insulin.", "content": "Cyclic AMP levels in various tissues of the domestic fowl (Gallus domesticus) as affected by glucagon, epinephrine and insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349797"}
{"pmid": "4349799", "title": "The effect of adenine nucleotides and dehydroepiandrosterone on the isoenzymes of NADP + -and NAD + -glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from rat adipose tissue.", "content": "The effect of adenine nucleotides and dehydroepiandrosterone on the isoenzymes of NADP + -and NAD + -glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from rat adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349799"}
{"pmid": "4349798", "title": "Adenylate cyclase and the function of cyclic adenosine 3':5'-monophosphate in the leucocidin-treated leucocyte.", "content": "Adenylate cyclase and the function of cyclic adenosine 3':5'-monophosphate in the leucocidin-treated leucocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349798"}
{"pmid": "4349793", "title": "Arterial baroreceptor fibers in the recurrent laryngeal nerve.", "content": "Arterial baroreceptor fibers in the recurrent laryngeal nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349793"}
{"pmid": "4349792", "title": "Mucociliary function during experimentally induced rhinovirus infection in man.", "content": "Mucociliary function during experimentally induced rhinovirus infection in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349792"}
{"pmid": "4349788", "title": "Medical and surgical management of stroke.", "content": "Medical and surgical management of stroke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349788"}
{"pmid": "4349791", "title": "A possible explanation for spontaneous breast development in XY gonadal dysgenesis.", "content": "A possible explanation for spontaneous breast development in XY gonadal dysgenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349791"}
{"pmid": "4349803", "title": "The antiquity of age-associated bone demineralization in man.", "content": "The antiquity of age-associated bone demineralization in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349803"}
{"pmid": "4349804", "title": "Adenohypophysis of foetal sheep: correlation of ultrastructure with functional activity.", "content": "Adenohypophysis of foetal sheep: correlation of ultrastructure with functional activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349804"}
{"pmid": "4349805", "title": "Structure and physiology of denervated and re-innervated cockroach muscle.", "content": "Structure and physiology of denervated and re-innervated cockroach muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349805"}
{"pmid": "4349806", "title": "Prevention by angiotensin II antiserum of drinking induced by intracranial angiotensin.", "content": "Prevention by angiotensin II antiserum of drinking induced by intracranial angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349806"}
{"pmid": "4349807", "title": "Early and late facilitation of transmission through a sympathetic ganglion and the influence of preganglionic B and C fibres.", "content": "Early and late facilitation of transmission through a sympathetic ganglion and the influence of preganglionic B and C fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349807"}
{"pmid": "4349808", "title": "Calcium release and vasopressin action in toad bladder.", "content": "Calcium release and vasopressin action in toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349808"}
{"pmid": "4349810", "title": "Surgical treatment of juvenile nasopharyngeal angiofibroma.", "content": "Surgical treatment of juvenile nasopharyngeal angiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349810"}
{"pmid": "4349811", "title": "Radiographic evaluation of the prevertebral space.", "content": "Radiographic evaluation of the prevertebral space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349811"}
{"pmid": "4349809", "title": "Electrophysiological identification of cell bodies of the tubero-infundibular neurones in the rat.", "content": "Electrophysiological identification of cell bodies of the tubero-infundibular neurones in the rat. 1. Electrical stimulation of the median eminence induced unit responses in the suprachiasmatic, the ventromedial and the arcuate nuclei of the hypothalamus in the female rat anaesthetized with urethane.2. Arcuate units with constant latency responded in one to one fashion to repetitive stimuli up to 286 Hz.3. A conditioning stimulus just above threshold increased the threshold and latency for responses produced by a test stimulus given within 6 msec after the conditioning stimulus. Absolute refractory period was 1.4-2.0msec.4. A conditioning stimulus just below threshold did not alter the threshold and latency of the responses to test stimuli at any interval.5. A stimulus given within a time period following a spontaneously occurring spike failed to induce a unit response.6. It is concluded that the arcuate nucleus of the hypothalamus includes cell bodies of origin of the tubero-infundibular axons in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349809"}
{"pmid": "4349813", "title": "The arterial wall and the process of atherosclerosis.", "content": "The arterial wall and the process of atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349813"}
{"pmid": "4349812", "title": "Effects on self-stimulation behavior of drugs influencing dopaminergic neurotransmission mechanisms.", "content": "Effects on self-stimulation behavior of drugs influencing dopaminergic neurotransmission mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349812"}
{"pmid": "4349794", "title": "Idiopathic facial palsy and pregnancy.", "content": "Idiopathic facial palsy and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349794"}
{"pmid": "4349816", "title": "Changes in neuron structure during action potential propagation and synaptic transmission.", "content": "Changes in neuron structure during action potential propagation and synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349816"}
{"pmid": "4349817", "title": "The in vitro assay of the herpesvirus of turkeys.", "content": "The in vitro assay of the herpesvirus of turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349817"}
{"pmid": "4349818", "title": "Karyological characterization of primary dog kidney cells in regard to acceptability of the cells as substrate of virus vaccines.", "content": "Karyological characterization of primary dog kidney cells in regard to acceptability of the cells as substrate of virus vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349818"}
{"pmid": "4349819", "title": "New trends in the preparation of cell substrates for the production of virus vaccines.", "content": "New trends in the preparation of cell substrates for the production of virus vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349819"}
{"pmid": "4349820", "title": "Replacement of serum by a soybean protein fraction in a basal tissue culture medium.", "content": "Replacement of serum by a soybean protein fraction in a basal tissue culture medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349820"}
{"pmid": "4349821", "title": "Consideration of immunological prophylaxis of tumours.", "content": "Consideration of immunological prophylaxis of tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349821"}
{"pmid": "4349822", "title": "General discussion the papers of session 3. Developments with viral vaccines.", "content": "General discussion the papers of session 3. Developments with viral vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349822"}
{"pmid": "4349823", "title": "Problems in the detection of the oncogenic potential of viruses or cell cultures.", "content": "Problems in the detection of the oncogenic potential of viruses or cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349823"}
{"pmid": "4349824", "title": "Carcinogenesis in germ-free animals.", "content": "Carcinogenesis in germ-free animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349824"}
{"pmid": "4349826", "title": "Search for oncogenes in human rhabdomyosarcoma cells.", "content": "Search for oncogenes in human rhabdomyosarcoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349826"}
{"pmid": "4349825", "title": "Natural history studies of the feline RNA tumor virus genoma. I. Detection of group specific antigen and C-type particles.", "content": "Natural history studies of the feline RNA tumor virus genoma. I. Detection of group specific antigen and C-type particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349825"}
{"pmid": "4349827", "title": "Cell tumourigenicity detected by heterotransplantation into mice immunosuppressed with anti-lymphocytic serum.", "content": "Cell tumourigenicity detected by heterotransplantation into mice immunosuppressed with anti-lymphocytic serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349827"}
{"pmid": "4349829", "title": "A bacterial protein inducing antiviral resistance and high titers of interferon.", "content": "A bacterial protein inducing antiviral resistance and high titers of interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349829"}
{"pmid": "4349828", "title": "Study of two double-stranded ribonucleic acids of viral origin: interferon inducing and antiviral activities.", "content": "Study of two double-stranded ribonucleic acids of viral origin: interferon inducing and antiviral activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349828"}
{"pmid": "4349830", "title": "Antiviral properties of five strains of Corynebacterium.", "content": "Antiviral properties of five strains of Corynebacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349830"}
{"pmid": "4349831", "title": "The development of different vaccine types against parainfluenza-3 in cattle.", "content": "The development of different vaccine types against parainfluenza-3 in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349831"}
{"pmid": "4349832", "title": "Safety and potency of parainfluenza-3 vaccines for cattle and test procedures.", "content": "Safety and potency of parainfluenza-3 vaccines for cattle and test procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349832"}
{"pmid": "4349833", "title": "Developments with bacterial vaccines: cholera.", "content": "Developments with bacterial vaccines: cholera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349833"}
{"pmid": "4349834", "title": "Possible reasons for the inefficiency of Gram-negative bacterial vaccines.", "content": "Possible reasons for the inefficiency of Gram-negative bacterial vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349834"}
{"pmid": "4349835", "title": "In vitro infection of sera containing Australia antigen.", "content": "In vitro infection of sera containing Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349835"}
{"pmid": "4349837", "title": "The effect of methotrexate and folinic acid therapy on the platelet count.", "content": "The effect of methotrexate and folinic acid therapy on the platelet count.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349837"}
{"pmid": "4349836", "title": "Brief latency click-evoked potentials during waking and sleep in man.", "content": "Brief latency click-evoked potentials during waking and sleep in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349836"}
{"pmid": "4349845", "title": "The inhibition of a p-nitrophenylphosphatase of Streptococcus mutans by fluoride ions.", "content": "The inhibition of a p-nitrophenylphosphatase of Streptococcus mutans by fluoride ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349845"}
{"pmid": "4349848", "title": "Pancreatic glucagon in health and disease.", "content": "Pancreatic glucagon in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349848"}
{"pmid": "4349849", "title": "Mammary adenoid cystic carcinoma with unusual features.", "content": "Mammary adenoid cystic carcinoma with unusual features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349849"}
{"pmid": "4349850", "title": "Myofiber inclusions.", "content": "Myofiber inclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349850"}
{"pmid": "4349852", "title": "Traumatic optic neuritis.", "content": "Traumatic optic neuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349852"}
{"pmid": "4349851", "title": "Collagenase inhibitors (penicillamine).", "content": "Collagenase inhibitors (penicillamine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349851"}
{"pmid": "4349855", "title": "Effects of (H + ), (Na + ), (K + ) and certain membrane-active drugs on glycolysis, motility, and ATP synthesis by human spermatozoa.", "content": "Effects of (H + ), (Na + ), (K + ) and certain membrane-active drugs on glycolysis, motility, and ATP synthesis by human spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349855"}
{"pmid": "4349856", "title": "Subacute demyelinating disease in an adult (diffuse-disseminated sclerosis). Electron microscopic findings.", "content": "Subacute demyelinating disease in an adult (diffuse-disseminated sclerosis). Electron microscopic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349856"}
{"pmid": "4349858", "title": "Epstein-Barr virus in human tumor cells.", "content": "Epstein-Barr virus in human tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349858"}
{"pmid": "4349859", "title": "The biology of the mouse mammary tumor virus.", "content": "The biology of the mouse mammary tumor virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349859"}
{"pmid": "4349861", "title": "Synthesis of mitochondrial deoxyribonucleic acid with a partially purified deoxyribonucleic acid polymerase from the mitochondria of HeLa cells.", "content": "Synthesis of mitochondrial deoxyribonucleic acid with a partially purified deoxyribonucleic acid polymerase from the mitochondria of HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349861"}
{"pmid": "4349860", "title": "Properties and mode of action of a partially purified deoxyribonucleic acid polymerase from the mitochondria of HeLa cells.", "content": "Properties and mode of action of a partially purified deoxyribonucleic acid polymerase from the mitochondria of HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349860"}
{"pmid": "4349862", "title": "Orientation of the cell membrane in ghosts and electron transport particles of Mycobacterium phlei.", "content": "Orientation of the cell membrane in ghosts and electron transport particles of Mycobacterium phlei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349862"}
{"pmid": "4349863", "title": "A comparison of associated enzyme activities in various deoxyribonucleic acid polymerases.", "content": "A comparison of associated enzyme activities in various deoxyribonucleic acid polymerases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349863"}
{"pmid": "4349857", "title": "Responses evoked from the thalamic centrum medianum by painful input: suppression by dorsal funiculus conditioning.", "content": "Responses evoked from the thalamic centrum medianum by painful input: suppression by dorsal funiculus conditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349857"}
{"pmid": "4349864", "title": "Cyanide-insensitive respiration. I. The steady states of skunk cabbage spadix and bean hypocotyl mitochondria.", "content": "Cyanide-insensitive respiration. I. The steady states of skunk cabbage spadix and bean hypocotyl mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349864"}
{"pmid": "4349865", "title": "Horse liver alcohol dehydrogenase. Amino groups and rate-limiting steps in catalysis.", "content": "Horse liver alcohol dehydrogenase. Amino groups and rate-limiting steps in catalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349865"}
{"pmid": "4349866", "title": "Mechanism of control of hepatic glycogenesis by insulin.", "content": "Mechanism of control of hepatic glycogenesis by insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349866"}
{"pmid": "4349867", "title": "Nicotinate phosphoribosyltransferase of human erythrocytes. Purification and properties.", "content": "Nicotinate phosphoribosyltransferase of human erythrocytes. Purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349867"}
{"pmid": "4349868", "title": "Interaction of concanavalin A and wheat germ agglutinin with the insulin receptor of fat cells and liver.", "content": "Interaction of concanavalin A and wheat germ agglutinin with the insulin receptor of fat cells and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349868"}
{"pmid": "4349869", "title": "Anthranilate synthetase of Acinetobacter calcoaceticus. Separation and partial characterization of subunits.", "content": "Anthranilate synthetase of Acinetobacter calcoaceticus. Separation and partial characterization of subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349869"}
{"pmid": "4349870", "title": "The endometrial adenosine cyclic 3':5'-monophosphate-dependent protein kinase. Distribution, subunit structure, and kinetics of adenosine cyclic 3':5'-monophosphate binding.", "content": "The endometrial adenosine cyclic 3':5'-monophosphate-dependent protein kinase. Distribution, subunit structure, and kinetics of adenosine cyclic 3':5'-monophosphate binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349870"}
{"pmid": "4349872", "title": "Structure-function relationships at the active site of nuclease-T'.", "content": "Structure-function relationships at the active site of nuclease-T'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349872"}
{"pmid": "4349873", "title": "Myocardial ultrastructure of young and senescent rats.", "content": "Myocardial ultrastructure of young and senescent rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349873"}
{"pmid": "4349871", "title": "Influence of glucagon on the metabolism of xylitol and dihydroxyacetone in the isolated perfused rat liver.", "content": "Influence of glucagon on the metabolism of xylitol and dihydroxyacetone in the isolated perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349871"}
{"pmid": "4349874", "title": "Periodic fibrillar material in membrane-bound bodies in notochordal epithelium of the early chick embryo.", "content": "Periodic fibrillar material in membrane-bound bodies in notochordal epithelium of the early chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349874"}
{"pmid": "4349875", "title": "Ultrastructure of sinus venosus innervation in Petromyzon marinus.", "content": "Ultrastructure of sinus venosus innervation in Petromyzon marinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349875"}
{"pmid": "4349877", "title": "From vitamin to hormone.", "content": "From vitamin to hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349877"}
{"pmid": "4349876", "title": "Electron microscopical study on the influence of the preparative conditions on contour length and structure of mitochondrial DNA of mouse liver.", "content": "Electron microscopical study on the influence of the preparative conditions on contour length and structure of mitochondrial DNA of mouse liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349876"}
{"pmid": "4349879", "title": "Age related changes of hematologic values in infant Macaca mulatta.", "content": "Age related changes of hematologic values in infant Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349879"}
{"pmid": "4349878", "title": "Synergistic role of intestinal flagellates and normal intestinal bacteria in a post-weaning mortality of mice.", "content": "Synergistic role of intestinal flagellates and normal intestinal bacteria in a post-weaning mortality of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349878"}
{"pmid": "4349880", "title": "Review of recent epizootics in nonhuman primate colonies and their relation to man.", "content": "Review of recent epizootics in nonhuman primate colonies and their relation to man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349880"}
{"pmid": "4349881", "title": "Filariasis in New World monkeys: histochemical differentiation of circulating microfilariae.", "content": "Filariasis in New World monkeys: histochemical differentiation of circulating microfilariae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349881"}
{"pmid": "4349882", "title": "Relationship of the vaginal smear to ovarian follicles and the uterus in postpartum Mongolian gerbils.", "content": "Relationship of the vaginal smear to ovarian follicles and the uterus in postpartum Mongolian gerbils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349882"}
{"pmid": "4349883", "title": "Infections among Thai gibbons and humans caused by atypical Microsporum canis.", "content": "Infections among Thai gibbons and humans caused by atypical Microsporum canis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349883"}
{"pmid": "4349884", "title": "Investigations into the diagnosis and spread of epizootic simian tubrculosis.", "content": "Investigations into the diagnosis and spread of epizootic simian tubrculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349884"}
{"pmid": "4349886", "title": "The Afghan pika (Ochotona refescens rufescens): a new laboratory animal.", "content": "The Afghan pika (Ochotona refescens rufescens): a new laboratory animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349886"}
{"pmid": "4349885", "title": "Immune and pathologic consequences of spontaneous Cuterebra myiasis in domestic rabbits (Oryctolagus cuniculus).", "content": "Immune and pathologic consequences of spontaneous Cuterebra myiasis in domestic rabbits (Oryctolagus cuniculus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349885"}
{"pmid": "4349887", "title": "Collection of chimpanzee semen with an artificial vagina.", "content": "Collection of chimpanzee semen with an artificial vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349887"}
{"pmid": "4349888", "title": "A simple method for skin grafting in germfree mice.", "content": "A simple method for skin grafting in germfree mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349888"}
{"pmid": "4349889", "title": "Pneumothorax associated with lung mite lesions in a rhesus monkey.", "content": "Pneumothorax associated with lung mite lesions in a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349889"}
{"pmid": "4349890", "title": "Growth, longevity, and reproductive life of the Mongolian gerbil.", "content": "Growth, longevity, and reproductive life of the Mongolian gerbil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349890"}
{"pmid": "4349891", "title": "A simple endotracheal intubation technic for inhalation anesthesia of the rat.", "content": "A simple endotracheal intubation technic for inhalation anesthesia of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349891"}
{"pmid": "4349893", "title": "Adamantinoma in a spider monkey (Ateles fusciceps).", "content": "Adamantinoma in a spider monkey (Ateles fusciceps).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349893"}
{"pmid": "4349892", "title": "Subclinical otitis media associated with Pasteurella multocida infections in New Zealand white rabbits (Oryctolagus cuniculus).", "content": "Subclinical otitis media associated with Pasteurella multocida infections in New Zealand white rabbits (Oryctolagus cuniculus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349892"}
{"pmid": "4349894", "title": "A collapsible restraint apparatus for cardiac bleeding of rabbits.", "content": "A collapsible restraint apparatus for cardiac bleeding of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349894"}
{"pmid": "4349895", "title": "Tattooing rabbits' ears for identification.", "content": "Tattooing rabbits' ears for identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349895"}
{"pmid": "4349896", "title": "Microsporidiosis (encephalitozoonosis) in the guinea pig.", "content": "Microsporidiosis (encephalitozoonosis) in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349896"}
{"pmid": "4349897", "title": "Thorns of South American clump palm trees in the thoracic organs of owl monkeys (Aotus trivirgatus).", "content": "Thorns of South American clump palm trees in the thoracic organs of owl monkeys (Aotus trivirgatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349897"}
{"pmid": "4349898", "title": "Note on the rabbit ovary.", "content": "Note on the rabbit ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349898"}
{"pmid": "4349899", "title": "Pathogenesis of intrauterine infections in rats due to reovirus type 3. I. Virologic studies.", "content": "Pathogenesis of intrauterine infections in rats due to reovirus type 3. I. Virologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349899"}
{"pmid": "4349900", "title": "Protein and messenger RNA requirements for superhelicity of polyoma virus DNA.", "content": "Protein and messenger RNA requirements for superhelicity of polyoma virus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349900"}
{"pmid": "4349901", "title": "DNA virus inhibitory activity of 1- -D-arabinofuranosylcytosine-3',5'-cyclic phosphate.", "content": "DNA virus inhibitory activity of 1- -D-arabinofuranosylcytosine-3',5'-cyclic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349901"}
{"pmid": "4349902", "title": "Differential effect of cytochalasin B on normal and transformed mouse cells.", "content": "Differential effect of cytochalasin B on normal and transformed mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349902"}
{"pmid": "4349905", "title": "Management of tumors of the parotid gland.", "content": "Management of tumors of the parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349905"}
{"pmid": "4349907", "title": "Nasopharyngeal cancer.", "content": "Nasopharyngeal cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349907"}
{"pmid": "4349906", "title": "Management of cancer of the parotid gland.", "content": "Management of cancer of the parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349906"}
{"pmid": "4349911", "title": "Collagenolytic activity in periodontal disease.", "content": "Collagenolytic activity in periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349911"}
{"pmid": "4349910", "title": "Bile acid excretion after disappearance of jaundice in intrahepatic cholestasis of infancy.", "content": "Bile acid excretion after disappearance of jaundice in intrahepatic cholestasis of infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349910"}
{"pmid": "4349912", "title": "Aunt Libby and her cure-alls.", "content": "Aunt Libby and her cure-alls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349912"}
{"pmid": "4349916", "title": "The interaction between the mitochondrial ATPase (F 1 ) and the ATPase inhibitor.", "content": "The interaction between the mitochondrial ATPase (F 1 ) and the ATPase inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349916"}
{"pmid": "4349915", "title": "Water and cytochrome oxidation-reduction reactions.", "content": "Water and cytochrome oxidation-reduction reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349915"}
{"pmid": "4349917", "title": "Cytochrome oxidase from Pseudomonas aeruginosa. I. Purification and some properties.", "content": "Cytochrome oxidase from Pseudomonas aeruginosa. I. Purification and some properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349917"}
{"pmid": "4349918", "title": "Cytochrome c-556, a di-heme protein from Pseudomonas aeruginosa.", "content": "Cytochrome c-556, a di-heme protein from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349918"}
{"pmid": "4349919", "title": "Electron paramagnetic resonance studies on nitrogenase. II. Interaction of adenosine 5'-triphosphate with azoferredoxin.", "content": "Electron paramagnetic resonance studies on nitrogenase. II. Interaction of adenosine 5'-triphosphate with azoferredoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349919"}
{"pmid": "4349920", "title": "Electron paramagnetic resonance studies on nitrogenase. 3. Function of magnesium adenosine 5'-triphosphate and adenosine 5'-diphosphate in catalysis by nitrogenase.", "content": "Electron paramagnetic resonance studies on nitrogenase. 3. Function of magnesium adenosine 5'-triphosphate and adenosine 5'-diphosphate in catalysis by nitrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349920"}
{"pmid": "4349922", "title": "The EPR spectrum of isolated complex 3.", "content": "The EPR spectrum of isolated complex 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349922"}
{"pmid": "4349923", "title": "Nuclear magnetic resonance study of the interaction of cytochrome c with cytochrome c peroxidase.", "content": "Nuclear magnetic resonance study of the interaction of cytochrome c with cytochrome c peroxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349923"}
{"pmid": "4349924", "title": "Biochemical basis for the toxic effects of triethyl lead.", "content": "Biochemical basis for the toxic effects of triethyl lead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349924"}
{"pmid": "4349925", "title": "Malignancy of bronchial adenoma.", "content": "Malignancy of bronchial adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349925"}
{"pmid": "4349928", "title": "The role of heparin in the chemotherapy of solid tumors: preliminary clinical trial in carcinoma of the lung.", "content": "The role of heparin in the chemotherapy of solid tumors: preliminary clinical trial in carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349928"}
{"pmid": "4349929", "title": "Influence of hormones on the growth of hepatomas and induction of adenylate and pyruvate kinases.", "content": "Influence of hormones on the growth of hepatomas and induction of adenylate and pyruvate kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349929"}
{"pmid": "4349930", "title": "Effect of alkylating antitumor agents on the binding of DNA to protein.", "content": "Effect of alkylating antitumor agents on the binding of DNA to protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349930"}
{"pmid": "4349931", "title": "The mineral content and water compartments of liver and of Morris hepatomata 5123tc and 3924A and the changes of composition occurring during necrosis in hepatoma 3924A.", "content": "The mineral content and water compartments of liver and of Morris hepatomata 5123tc and 3924A and the changes of composition occurring during necrosis in hepatoma 3924A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349931"}
{"pmid": "4349932", "title": "The net extrusion of calcium and its temporal relation to the accumulation of potassium in slices of rat liver and of Morris hepatomata 5123tc and 3924A.", "content": "The net extrusion of calcium and its temporal relation to the accumulation of potassium in slices of rat liver and of Morris hepatomata 5123tc and 3924A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349932"}
{"pmid": "4349933", "title": "Lysosomal hyaluronidase activity in normal rat liver and in chemically induced hepatomas.", "content": "Lysosomal hyaluronidase activity in normal rat liver and in chemically induced hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349933"}
{"pmid": "4349934", "title": "Orotate phosphoribosyl transferase and orotidylic acid decarboxylase activities in liver and Morris hepatomas.", "content": "Orotate phosphoribosyl transferase and orotidylic acid decarboxylase activities in liver and Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349934"}
{"pmid": "4349935", "title": "A morphological and histochemical study of carcinogenesis of the liver in rats fed 3'-methyl-4-dimethylaminoazobenzene.", "content": "A morphological and histochemical study of carcinogenesis of the liver in rats fed 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349935"}
{"pmid": "4349936", "title": "Partial characterization of the DNA-dependent DNA polymerases of rat liver and hepatoma.", "content": "Partial characterization of the DNA-dependent DNA polymerases of rat liver and hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349936"}
{"pmid": "4349938", "title": "The influence of dibutyryl cyclic adenosine monophosphate and other substances on human bronchial mucous gland discharge.", "content": "The influence of dibutyryl cyclic adenosine monophosphate and other substances on human bronchial mucous gland discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349938"}
{"pmid": "4349939", "title": "Arterial endothelial permeability and vascular disease. The \"trap door\" effect.", "content": "Arterial endothelial permeability and vascular disease. The \"trap door\" effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349939"}
{"pmid": "4349941", "title": "The ageing pattern of human intervertebral disc.", "content": "The ageing pattern of human intervertebral disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349941"}
{"pmid": "4349943", "title": "Formation of H adduct radicals in cytosine and its derivatives.", "content": "Formation of H adduct radicals in cytosine and its derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349943"}
{"pmid": "4349944", "title": "Pseudoachondroplastic dwarfism. A rough-surfaced endoplasmic reticulum storage disorder.", "content": "Pseudoachondroplastic dwarfism. A rough-surfaced endoplasmic reticulum storage disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349944"}
{"pmid": "4349945", "title": "Metaphyseal dysotosis: description of an ultrastructural defect in the epiphyseal plate chondrocytes.", "content": "Metaphyseal dysotosis: description of an ultrastructural defect in the epiphyseal plate chondrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349945"}
{"pmid": "4349937", "title": "Carcinoma of the rectum: treatment by anterior resection or abdominoperineal excision?", "content": "Carcinoma of the rectum: treatment by anterior resection or abdominoperineal excision?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349937"}
{"pmid": "4349946", "title": "Alterations in cyclic AMP metabolism in human bronchial asthma. II. Leukocyte and lymphocyte responses to prostaglandins.", "content": "Alterations in cyclic AMP metabolism in human bronchial asthma. II. Leukocyte and lymphocyte responses to prostaglandins. In an effort to clarify the basis for the reduced cyclic AMP response to catecholamines in leukocytes and lymphocytes from asthmatic donors the response of these cells to prostaglandins has been examined. Cells with an impaired beta adrenergic response had an essentially unaltered response to prostaglandin E(1) (PGE(1)) indicating the presence of selective beta adrenergic blockade. In contrast to what was observed with cells from asthmatic individuals, in normal control leukocytes with reduced catecholamine responsiveness PGE(1) responses were usually reduced as well, suggesting a different mechanism. The excellent cyclic AMP response to PGE(1) in cells from asthmatic donors would suggest that the defect in catecholamine responsiveness is at the level of the beta adrenergic receptor although a contributory role of altered substrate concentrations or increased phosphodiesterase activity is not formally excluded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349946"}
{"pmid": "4349947", "title": "Alterations in cyclic AMP metabolism in human bronchial asthma. 3. Leukocyte and lymphocyte responses to steroids.", "content": "Alterations in cyclic AMP metabolism in human bronchial asthma. 3. Leukocyte and lymphocyte responses to steroids. On the basis of serial studies the responsiveness of leukocytes and lymphocytes from asthmatic donors to catecholamines was increased during high dose corticosteroid therapy. Similar changes were observed in the cells of normal control subjects given 200 mg of hydrocortisone intravenously. The increase in responsiveness did not appear to be due to changes in lymphocyte subpopulations although this may be a contributing factor. In an effort to elucidate the basis for the improved response, in vitro effects of glucocorticoids on lymphocyte cyclic AMP concentrations were investigated. Glucocorticoids (prednisolone succinate, hydrocortisone, hydrocortisone phosphate, and hydrocortisone succinate) stimulated cyclic AMP accumulation in asthma and normal control lymphocytes, increases occurring within the first 2 min of incubation. In the absence of theophylline, responses were regularly obtained at 10 muM hydrocortisone and usually at 1 muM hydrocortisone but not at submicromolar steroid concentrations. Theophylline potentiated the cyclic AMP response to glucocorticoids and also increased the percentage of positive responses in the 0.01-1.0 muM corticosteroid range. Combinations of 1 muM hydrocortisone and 1 muM epinephrine were sometimes additive or synergistic but in many instances higher glucocorticoid concentrations were needed to obtain augmentation of the catecholamine response. The in vitro glucocorticoid effects may not fully explain their potentiating action in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349947"}
{"pmid": "4349948", "title": "Effects of cycloheximide on the response of intestinal mucosa to cholera enterotoxin.", "content": "Effects of cycloheximide on the response of intestinal mucosa to cholera enterotoxin. Prior studies have indicated that effects of cholera enterotoxin (CT) on the small intestine are delayed in onset and involve an interaction with adenyl cyclase in the mucosa. It has also been shown that the administration of cycloheximide to rabbits in doses which inhibit crypt cell mitoses (20 mg/kg), diminishes CT-induced fluid production in jejunal loops. These latter studies have been interpreted as indications that CT-related intestinal secretion is a crypt cell function and that it is mediated by a CT-induced protein. The present study was undertaken to delineate more precisely the nature of the interaction in the intestine between cycloheximide and cholera toxin. Pretreatment of rabbits with cycloheximide reduced by 60% the secretory response to CT in isolated ileal loops with intact blood supply. Sodium and chloride flux measurements on mucosa isolated from these and control loops indicated that this antisecretory effect of cycloheximide persists in vitro. Measurements of radioactive leucine incorporation into mucosal protein indicated that the dose of cycloheximide employed inhibited protein synthesis by 90%. This inhibitory effect was shown to be independent of any effect of cycloheximide on amino acid uptake across the brush border. Measurements of adenyl cyclase activity and cyclic AMP levels in ileal mucosa of cycloheximide pretreated and control animals indicated that cycloheximide did not diminish the CT-induced increases in these parameters. These observations demonstrate that cycloheximide reduces CT-induced intestinal fluid production without interfering with the CT-induced augmentation of adenyl cyclase activity or the consequent rise in cyclic. AMP concentration. Since the antisecretory effect of cycloheximide persists in vitro, it probably involves a direct interaction of the antibiotic with mucosal cell ion transport mechanisms rather than an indirect effect mediated by other humoral or neurogenic factors. The present observations also suggest that the secretory response of the intestine to CT involves neither the synthesis of new adenyl cyclase nor that of a protein modifying its activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349948"}
{"pmid": "4349950", "title": "The interconversion of oestrone and oestradiol-17  and the concentration of oestradiol-17  receptors in cultured rabbit uterus.", "content": "The interconversion of oestrone and oestradiol-17  and the concentration of oestradiol-17  receptors in cultured rabbit uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349950"}
{"pmid": "4349949", "title": "Effect of conjugated dihydroxy bile salts on electrolyte transport in rat colon.", "content": "Effect of conjugated dihydroxy bile salts on electrolyte transport in rat colon. The mechanism by which excess quantities of bile salts in the colon produce diarrhea is not known. Therefore, experiments were performed in which the effect of conjugated dihydroxy bile salts on ion transport was evaluated in the in vitro short-circuited rat colon. 2 mM glycochenodeoxycholic acid (GCDC), taurochenodeoxycholic acid (TCDC), or taurodeoxycholic acid caused a prompt increase in short-circuit current (I(sc)) and electrical potential difference (PD). Similar results were obtained when theophylline was added. Removal of HCO(2) and C1 prevented the effects of both bile salts and theophylline. Pretreatment with theophylline blocked the increase in I(sc) and PD produced by TCDC and pretreatment with either TCDC or GCDC inhibited the expected theophylline response. Na fluxes in the presence of both TCDC and theophylline demonstrated a decrease in net absorption; and TCDC decreased net C1 absorption and theophylline caused a reversal of net C1 absorption to net C1 secretion. It is proposed that the diarrhea associated with cholerheic enteropathy is produced by active anion secretion possibly mediated by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349949"}
{"pmid": "4349951", "title": "Effect of oestrogen upon parturition, maternal behaviour and lactation in ovariectomized pregnant rats.", "content": "Effect of oestrogen upon parturition, maternal behaviour and lactation in ovariectomized pregnant rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349951"}
{"pmid": "4349952", "title": "The relationship of the splanchnic, hepatic and renal clearance rates to the metabolic clearance rate of cortisol in conscious sheep.", "content": "The relationship of the splanchnic, hepatic and renal clearance rates to the metabolic clearance rate of cortisol in conscious sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349952"}
{"pmid": "4349953", "title": "The role of transcortin in the regulation of corticotrophin secretion.", "content": "The role of transcortin in the regulation of corticotrophin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349953"}
{"pmid": "4349954", "title": "Morphological differentiation of adrenal cortical cells induced by a 40-minute exposure to corticotrophin.", "content": "Morphological differentiation of adrenal cortical cells induced by a 40-minute exposure to corticotrophin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349954"}
{"pmid": "4349955", "title": "Effect of adrenocorticotrophin on 21- and 11 -hydroxylase activity in the biosynthesis of cortisol.", "content": "Effect of adrenocorticotrophin on 21- and 11 -hydroxylase activity in the biosynthesis of cortisol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349955"}
{"pmid": "4349957", "title": "The innervation of the juxtaglomerular apparatus and surrounding tubules: a quantitative analysis by serial section electron microscopy.", "content": "The innervation of the juxtaglomerular apparatus and surrounding tubules: a quantitative analysis by serial section electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349957"}
{"pmid": "4349958", "title": "Ultrastructural features of cellular maturation and aging in human trophoblast.", "content": "Ultrastructural features of cellular maturation and aging in human trophoblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349958"}
{"pmid": "4349960", "title": "Association between endoplasmic reticulum and vacuoles in frozen-etched root tips.", "content": "Association between endoplasmic reticulum and vacuoles in frozen-etched root tips.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349960"}
{"pmid": "4349962", "title": "Effect of organic phosphates on the magnetic susceptibility of human deoxyhaemoglobin.", "content": "Effect of organic phosphates on the magnetic susceptibility of human deoxyhaemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349962"}
{"pmid": "4349963", "title": "Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver.", "content": "Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349963"}
{"pmid": "4349964", "title": "The role of the community nurse concerned with after-care.", "content": "The role of the community nurse concerned with after-care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349964"}
{"pmid": "4349968", "title": "Corticoids and respiratory distress.", "content": "Corticoids and respiratory distress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349968"}
{"pmid": "4349967", "title": "Serum total corticoid and cortisol levels in premature infants with respiratory distress syndrome.", "content": "Serum total corticoid and cortisol levels in premature infants with respiratory distress syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349967"}
{"pmid": "4349969", "title": "Silica urolithiasis in dogs fed an atherogenic diet.", "content": "Silica urolithiasis in dogs fed an atherogenic diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349969"}
{"pmid": "4349970", "title": "Antiviral immune hemolysis.", "content": "Antiviral immune hemolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349970"}
{"pmid": "4349971", "title": "Interferon induction by rhinoviruses and effect of interferon on rhinovirus yields in human cell lines.", "content": "Interferon induction by rhinoviruses and effect of interferon on rhinovirus yields in human cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349971"}
{"pmid": "4349972", "title": "Uranyl nitrate induced acute renal failure in the rat: effect of varying doses and saline loading.", "content": "Uranyl nitrate induced acute renal failure in the rat: effect of varying doses and saline loading.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349972"}
{"pmid": "4349973", "title": "The cytotoxic effect of human immune sera on Herpesvirus hominis infected cells.", "content": "The cytotoxic effect of human immune sera on Herpesvirus hominis infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349973"}
{"pmid": "4349974", "title": "Collagenase activity in tissues of selenium responsive myopathic lambs.", "content": "Collagenase activity in tissues of selenium responsive myopathic lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349974"}
{"pmid": "4349975", "title": "Effect of adrenal arterial infusion of different Mg 2+  concentrations on the spontaneous release of catecholamines in the anesthetized dog.", "content": "Effect of adrenal arterial infusion of different Mg 2+  concentrations on the spontaneous release of catecholamines in the anesthetized dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349975"}
{"pmid": "4349976", "title": "Ovarian weight changes in immature female rats as a function of dose and exposure time to PMS.", "content": "Ovarian weight changes in immature female rats as a function of dose and exposure time to PMS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349976"}
{"pmid": "4349977", "title": "Angiotensins lung converting enzyme.", "content": "Angiotensins lung converting enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349977"}
{"pmid": "4349979", "title": "An artifact resembling silver grains found in microautoradiography of lettuce fruits.", "content": "An artifact resembling silver grains found in microautoradiography of lettuce fruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349979"}
{"pmid": "4349978", "title": "Differentiation of nephrotensin from angiotensin I and II.", "content": "Differentiation of nephrotensin from angiotensin I and II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349978"}
{"pmid": "4349981", "title": "Partial mastectomy for carcinoma of the breast.", "content": "Partial mastectomy for carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349981"}
{"pmid": "4349982", "title": "Subcutaneous glomus tumors.", "content": "Subcutaneous glomus tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349982"}
{"pmid": "4349983", "title": "A comparison of the treatment of gas gangrene with and without hyperbaric oxygen.", "content": "A comparison of the treatment of gas gangrene with and without hyperbaric oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349983"}
{"pmid": "4349985", "title": "Scanning electron microscopy of erythrocytes adsorbed by ribonucleic acid virus-infected cells in vitro.", "content": "Scanning electron microscopy of erythrocytes adsorbed by ribonucleic acid virus-infected cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349985"}
{"pmid": "4349984", "title": "Comparative study of experimental Clostridium perfringens infection in dogs treated with antibiotics, surgery, and hyperbaric oxygen.", "content": "Comparative study of experimental Clostridium perfringens infection in dogs treated with antibiotics, surgery, and hyperbaric oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349984"}
{"pmid": "4349986", "title": "Naturally occurring infection of calves with a bovine adenovirus.", "content": "Naturally occurring infection of calves with a bovine adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349986"}
{"pmid": "4349987", "title": "C-type virus particles in avian bursa of Fabricius cells grown in vitro.", "content": "C-type virus particles in avian bursa of Fabricius cells grown in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349987"}
{"pmid": "4349988", "title": "Distribution of thyroid, parathyroid, and ultimobranchial hypocalcemic factors in birds. II. Morphology, histochemistry, and hypocalcemic activity of pigeon thyroid glands.", "content": "Distribution of thyroid, parathyroid, and ultimobranchial hypocalcemic factors in birds. II. Morphology, histochemistry, and hypocalcemic activity of pigeon thyroid glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349988"}
{"pmid": "4349991", "title": "Kinetic and electrophoretic abnormality of cyclic AMP phosphodiesterase in genetically obese mouse adipocytes.", "content": "Kinetic and electrophoretic abnormality of cyclic AMP phosphodiesterase in genetically obese mouse adipocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349991"}
{"pmid": "4349992", "title": "Effects of progesterone on the binding of estradiol-receptor to rabbit uterine chromatin.", "content": "Effects of progesterone on the binding of estradiol-receptor to rabbit uterine chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349992"}
{"pmid": "4349993", "title": "Reactive lysine residues in horse liver alcohol dehydrogenase.", "content": "Reactive lysine residues in horse liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349993"}
{"pmid": "4349994", "title": "Topography of nucleic acid helices in solutions. 28. Evidence for a dynamic structure of DNA in solution.", "content": "Topography of nucleic acid helices in solutions. 28. Evidence for a dynamic structure of DNA in solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349994"}
{"pmid": "4349995", "title": "Inhibitor of adenosine 3',5'-monophosphate binding and protein kinase activity in leucocyte lysosomes.", "content": "Inhibitor of adenosine 3',5'-monophosphate binding and protein kinase activity in leucocyte lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349995"}
{"pmid": "4349996", "title": "Lack of influence of mitochondrial genetical information on the multiplication of Herpes simplex virus in HeLa cells.", "content": "Lack of influence of mitochondrial genetical information on the multiplication of Herpes simplex virus in HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349996"}
{"pmid": "4349997", "title": "Resonance Raman scattering on the haem group of cytochrome c.", "content": "Resonance Raman scattering on the haem group of cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349997"}
{"pmid": "4349998", "title": "The presence of  -mannosidic linkage in acidic glycopeptide from porcine thyroglobulin.", "content": "The presence of  -mannosidic linkage in acidic glycopeptide from porcine thyroglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349998"}
{"pmid": "4349999", "title": "Two-dimensional polyacrylamide gel electrophoresis of acid extractable nuclear proteins of normal rat liver and Novikoff hepatoma ascites cells.", "content": "Two-dimensional polyacrylamide gel electrophoresis of acid extractable nuclear proteins of normal rat liver and Novikoff hepatoma ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349999"}
{"pmid": "4349989", "title": "Some current concepts of the pneumoconioses.", "content": "Some current concepts of the pneumoconioses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4349989"}
{"pmid": "4350000", "title": "Differences in the metabolism of phospholipids depending on cell population density.", "content": "Differences in the metabolism of phospholipids depending on cell population density.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350000"}
{"pmid": "4350001", "title": "Effect of ribosomal protein L12 upon initiation factor IF-2 activities.", "content": "Effect of ribosomal protein L12 upon initiation factor IF-2 activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350001"}
{"pmid": "4350002", "title": "Assembly and secretion of very low density lipoproteins by rat liver following inhibition of protein synthesis with cycloheximide.", "content": "Assembly and secretion of very low density lipoproteins by rat liver following inhibition of protein synthesis with cycloheximide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350002"}
{"pmid": "4350003", "title": "Colchicine-induced inhibition of very low density lipoprotein release by rat liver in vivo.", "content": "Colchicine-induced inhibition of very low density lipoprotein release by rat liver in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350003"}
{"pmid": "4350012", "title": "Methanesulfonates: the relationship of structure to antitumor activity.", "content": "Methanesulfonates: the relationship of structure to antitumor activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350012"}
{"pmid": "4350004", "title": "Foot-and-mouth disease circulating antibodies in convalescent cattle.", "content": "Foot-and-mouth disease circulating antibodies in convalescent cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350004"}
{"pmid": "4350014", "title": "Ventilatory effects of aerosolized kanamycin and polymyxin.", "content": "Ventilatory effects of aerosolized kanamycin and polymyxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350014"}
{"pmid": "4350013", "title": "Effect of compounds on a spectrum of rat tumors.", "content": "Effect of compounds on a spectrum of rat tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350013"}
{"pmid": "4350015", "title": "Granular cell myoblastoma of trachea associated with pregnancy.", "content": "Granular cell myoblastoma of trachea associated with pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350015"}
{"pmid": "4350016", "title": "Rapid method for screening for galactosemia and galactokinase deficiency by measuring galactose in whole blood spotted on paper.", "content": "Rapid method for screening for galactosemia and galactokinase deficiency by measuring galactose in whole blood spotted on paper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350016"}
{"pmid": "4350006", "title": "Pathogenesis of foot-and-mouth disease in experimentally infected pigs.", "content": "Pathogenesis of foot-and-mouth disease in experimentally infected pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350006"}
{"pmid": "4350018", "title": "Effects of a partially purified factor from chick embryos on macromolecular synthesis of embryonic pancreatic epithelia.", "content": "Effects of a partially purified factor from chick embryos on macromolecular synthesis of embryonic pancreatic epithelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350018"}
{"pmid": "4350017", "title": "Stability of erythrocytic enzymes for screening tests.", "content": "Stability of erythrocytic enzymes for screening tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350017"}
{"pmid": "4350019", "title": "A genically determined abnormality in the number and arrangement of basal bodies in a ciliate.", "content": "A genically determined abnormality in the number and arrangement of basal bodies in a ciliate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350019"}
{"pmid": "4350020", "title": "Decreased formation of syncytial plaques in the XC-test with a double-cloned hypotetraploid XC-cell line and evidence of budding C-type particles in this and ordinary hypodiploid XC-cell lines.", "content": "Decreased formation of syncytial plaques in the XC-test with a double-cloned hypotetraploid XC-cell line and evidence of budding C-type particles in this and ordinary hypodiploid XC-cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350020"}
{"pmid": "4350021", "title": "A method of recording nerve terminal activity in the frog.", "content": "A method of recording nerve terminal activity in the frog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350021"}
{"pmid": "4350022", "title": "Diffusion of pyrimethamine from silicone rubber and flexible epoxy drug capsules.", "content": "Diffusion of pyrimethamine from silicone rubber and flexible epoxy drug capsules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350022"}
{"pmid": "4350023", "title": "Alteration of immunocompetence by mammary tumor virus.", "content": "Alteration of immunocompetence by mammary tumor virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350023"}
{"pmid": "4350024", "title": "Brief communication: specific transplantation antigens of murine neoplasms induced by visna and progressive pneumonia viruses.", "content": "Brief communication: specific transplantation antigens of murine neoplasms induced by visna and progressive pneumonia viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350024"}
{"pmid": "4350025", "title": "Question: do herpesviruses cause cancer? Answer: of course they do.", "content": "Question: do herpesviruses cause cancer? Answer: of course they do.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350025"}
{"pmid": "4350026", "title": "L-asparaginase-induced alterations of Burkitt's lymphoma cells.", "content": "L-asparaginase-induced alterations of Burkitt's lymphoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350026"}
{"pmid": "4350028", "title": "Inhibition of growth and transformation of human cells by interferon.", "content": "Inhibition of growth and transformation of human cells by interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350028"}
{"pmid": "4350027", "title": "Isolation of plasma membrane antigens from Epstein-Barr virus-infected lymphoid cells.", "content": "Isolation of plasma membrane antigens from Epstein-Barr virus-infected lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350027"}
{"pmid": "4350029", "title": "Ultrastructural and complement-fixation studies on suspension cultures derived from human solid tumors.", "content": "Ultrastructural and complement-fixation studies on suspension cultures derived from human solid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350029"}
{"pmid": "4350030", "title": "Induction of tumors in the liver of hamsters by an avian adenovirus (CELO).", "content": "Induction of tumors in the liver of hamsters by an avian adenovirus (CELO).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350030"}
{"pmid": "4350031", "title": "Mouse strain-related differences in the biologic and immunologic responses to a murine sarcoma virus.", "content": "Mouse strain-related differences in the biologic and immunologic responses to a murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350031"}
{"pmid": "4350032", "title": "Lipid composition of Quaking mouse myelin: comparison with normal mouse myelin in the adult and during development.", "content": "Lipid composition of Quaking mouse myelin: comparison with normal mouse myelin in the adult and during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350032"}
{"pmid": "4350034", "title": "Serum glucose-6-phosphatase levels in normal pregnancy.", "content": "Serum glucose-6-phosphatase levels in normal pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350034"}
{"pmid": "4350033", "title": "GABA transport by nerve ending fractions of cat brain.", "content": "GABA transport by nerve ending fractions of cat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350033"}
{"pmid": "4350035", "title": "A case of genital herpesvirus infection in pregnancy.", "content": "A case of genital herpesvirus infection in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350035"}
{"pmid": "4350036", "title": "Schistosome motility measurements: response to drugs.", "content": "Schistosome motility measurements: response to drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350036"}
{"pmid": "4350037", "title": "Cyclic adenosine monophosphate antagonism of morphine analgesia.", "content": "Cyclic adenosine monophosphate antagonism of morphine analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350037"}
{"pmid": "4350038", "title": "Effects of cyclic 3',5'-adenosine monophosphate on morphine tolerance and physical dependence.", "content": "Effects of cyclic 3',5'-adenosine monophosphate on morphine tolerance and physical dependence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350038"}
{"pmid": "4350040", "title": "Study of phosphodiesterase inhibitors on lipolysis, phosphodiesterase activity and cyclic 3',5'-adenosine monophosphate levels in isolated fat cells.", "content": "Study of phosphodiesterase inhibitors on lipolysis, phosphodiesterase activity and cyclic 3',5'-adenosine monophosphate levels in isolated fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350040"}
{"pmid": "4350039", "title": "Characterization of the adrenergic receptors mediating a rise in cyclic 3'-5'-adenosine monophosphate in rat cerebral cortex.", "content": "Characterization of the adrenergic receptors mediating a rise in cyclic 3'-5'-adenosine monophosphate in rat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350039"}
{"pmid": "4350041", "title": "A possible etiology of contractility impairment of vascular smooth muscle from spontaneously hypertensive rats.", "content": "A possible etiology of contractility impairment of vascular smooth muscle from spontaneously hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350041"}
{"pmid": "4350042", "title": "Intravenously given conjugated estrogens. Lack of effect of capillary stability.", "content": "Intravenously given conjugated estrogens. Lack of effect of capillary stability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350042"}
{"pmid": "4350043", "title": "Vitamin D: a reawakening.", "content": "Vitamin D: a reawakening.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350043"}
{"pmid": "4350045", "title": "The effect of variations in LET and cell cycle on radiation hepatocarcinogenesis.", "content": "The effect of variations in LET and cell cycle on radiation hepatocarcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350045"}
{"pmid": "4350049", "title": "A qualitative and quantitative analysis of cuneate and gracile nuclei and of the dorsal column fibres.", "content": "A qualitative and quantitative analysis of cuneate and gracile nuclei and of the dorsal column fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350049"}
{"pmid": "4350053", "title": "The sleep polygram: a potentially useful tool for clinical assessment in human infants.", "content": "The sleep polygram: a potentially useful tool for clinical assessment in human infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350053"}
{"pmid": "4350054", "title": "On the significance of curvilinear bodies in late infantile lipidosis.", "content": "On the significance of curvilinear bodies in late infantile lipidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350054"}
{"pmid": "4350055", "title": "Fetal renal hamartoma--a benign tumor to be distinguished from Wilms' tumor. Report of 3 cases.", "content": "Fetal renal hamartoma--a benign tumor to be distinguished from Wilms' tumor. Report of 3 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350055"}
{"pmid": "4350058", "title": "Endometriosis of the bowel: role of bowel resection, superficial excision and oophorectomy in treatment.", "content": "Endometriosis of the bowel: role of bowel resection, superficial excision and oophorectomy in treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350058"}
{"pmid": "4350059", "title": "Significance of postoperative estrogen therapy on the occurrence and clinical course of cancer.", "content": "Significance of postoperative estrogen therapy on the occurrence and clinical course of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350059"}
{"pmid": "4350060", "title": "Diphosphoglycerate mutase and 2,3-diphosphoglycerate phosphatase activities of red cells: comparative electrophoretic study.", "content": "Diphosphoglycerate mutase and 2,3-diphosphoglycerate phosphatase activities of red cells: comparative electrophoretic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350060"}
{"pmid": "4350061", "title": "On the regulation of cyclic 3',5' adenosine monophosphate levels in bacteria. Stimulation of adenyl cyclase activity in vitro by glucose in a mutant of E. coli B-r.", "content": "On the regulation of cyclic 3',5' adenosine monophosphate levels in bacteria. Stimulation of adenyl cyclase activity in vitro by glucose in a mutant of E. coli B-r.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350061"}
{"pmid": "4350063", "title": "Electron paramagnetic resonance of single crystal deoxycobaltohemoglobin.", "content": "Electron paramagnetic resonance of single crystal deoxycobaltohemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350063"}
{"pmid": "4350062", "title": "pH profiles of proline transport with membrane vesicles from Mycobacterium phlei with artificial and natural electron donors.", "content": "pH profiles of proline transport with membrane vesicles from Mycobacterium phlei with artificial and natural electron donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350062"}
{"pmid": "4350064", "title": "The detection of a bound ferredoxin in the photosynthetic lamellae of blue-green algae and other oxygen evolving photosynthetic organisms.", "content": "The detection of a bound ferredoxin in the photosynthetic lamellae of blue-green algae and other oxygen evolving photosynthetic organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350064"}
{"pmid": "4350065", "title": "Chain non-equivalence in nitric oxide binding to hemoglobin.", "content": "Chain non-equivalence in nitric oxide binding to hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350065"}
{"pmid": "4350066", "title": "Differences in the physical properties of collagenases isolated from rheumatoid synovium and human skin.", "content": "Differences in the physical properties of collagenases isolated from rheumatoid synovium and human skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350066"}
{"pmid": "4350067", "title": "Ion and pH gradients across the transport membrane of mitochondria following Mn ++  uptake in the presence of acetate.", "content": "Ion and pH gradients across the transport membrane of mitochondria following Mn ++  uptake in the presence of acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350067"}
{"pmid": "4350068", "title": "Site of impairment of oxidative phosphorylation in irradiated rats.", "content": "Site of impairment of oxidative phosphorylation in irradiated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350068"}
{"pmid": "4350069", "title": "Studies on the accessibility barrier of NADH to cytochromes b in pigeon-heart mitochondria.", "content": "Studies on the accessibility barrier of NADH to cytochromes b in pigeon-heart mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350069"}
{"pmid": "4350071", "title": "Studies on electron transport associated with photosystem I. I. Functional site of plastocyanin: inhibitory effects of HgCl 2  on electron transport and plastocyanin in chloroplasts.", "content": "Studies on electron transport associated with photosystem I. I. Functional site of plastocyanin: inhibitory effects of HgCl 2  on electron transport and plastocyanin in chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350071"}
{"pmid": "4350056", "title": "Reduction of the tetrazolium salts in cells and tissue sections incubated without substrate.", "content": "Reduction of the tetrazolium salts in cells and tissue sections incubated without substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350056"}
{"pmid": "4350072", "title": "The use of ketamine hydrochloride anaesthesia for radiotherapy in young children.", "content": "The use of ketamine hydrochloride anaesthesia for radiotherapy in young children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350072"}
{"pmid": "4350076", "title": "Effects of methallibure on early pregnancy in swine.", "content": "Effects of methallibure on early pregnancy in swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350076"}
{"pmid": "4350075", "title": "Fat mobilizing lipase in relation to fatness in lambs.", "content": "Fat mobilizing lipase in relation to fatness in lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350075"}
{"pmid": "4350078", "title": "Corticosteroidogenesis in isolated adrenal cells: effect of adrenocorticotrophic hormone, adenosine 3',5'-monophosphate and   1-24  adrenocorticotrophic hormone diazotized to polyacrylamide.", "content": "Corticosteroidogenesis in isolated adrenal cells: effect of adrenocorticotrophic hormone, adenosine 3',5'-monophosphate and   1-24  adrenocorticotrophic hormone diazotized to polyacrylamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350078"}
{"pmid": "4350077", "title": "Interference of some pesticides in the milk phosphatase pasteurization test.", "content": "Interference of some pesticides in the milk phosphatase pasteurization test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350077"}
{"pmid": "4350079", "title": "The zona glomerulosa and corticotrophin: a genetic study in mice.", "content": "The zona glomerulosa and corticotrophin: a genetic study in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350079"}
{"pmid": "4350080", "title": "Regulation of the permeability to water in toad urinary bladder: the effect of copper.", "content": "Regulation of the permeability to water in toad urinary bladder: the effect of copper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350080"}
{"pmid": "4350081", "title": "A comparison of the effects of pituitary hormones and aminophylline on progestational hormone production by the rabbit ovary in vivo.", "content": "A comparison of the effects of pituitary hormones and aminophylline on progestational hormone production by the rabbit ovary in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350081"}
{"pmid": "4350082", "title": "Promotion of pituitary prolactin release in rats by dibutyryl adenosine 3',5'-monophosphate.", "content": "Promotion of pituitary prolactin release in rats by dibutyryl adenosine 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350082"}
{"pmid": "4350083", "title": "The conversion of angiotensin I to angiotensin II by rabbit glomeruli.", "content": "The conversion of angiotensin I to angiotensin II by rabbit glomeruli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350083"}
{"pmid": "4350084", "title": "Adrenal and testicular contribution to plasma oestrogens.", "content": "Adrenal and testicular contribution to plasma oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350084"}
{"pmid": "4350085", "title": "Quantitative study on RNA metabolism in mononucleate and Sendai virus-induced multinucleate cells.", "content": "Quantitative study on RNA metabolism in mononucleate and Sendai virus-induced multinucleate cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350085"}
{"pmid": "4350086", "title": "Sleep and activity in a psychotic depression.", "content": "Sleep and activity in a psychotic depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350086"}
{"pmid": "4350074", "title": "Prevalence of deformities and disabilities among leprosy patients in an endemic area. II. Nerve involvement in the limbs.", "content": "Prevalence of deformities and disabilities among leprosy patients in an endemic area. II. Nerve involvement in the limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350074"}
{"pmid": "4350087", "title": "Multiple pulmonary metastases from adenoid cystic carcinoma of ceruminous glands of external auditory canal. A case report and review of the literature.", "content": "Multiple pulmonary metastases from adenoid cystic carcinoma of ceruminous glands of external auditory canal. A case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350087"}
{"pmid": "4350098", "title": "Cholestyramine: factors limiting its antidiarrheal effect in patients resected for regional enteritis.", "content": "Cholestyramine: factors limiting its antidiarrheal effect in patients resected for regional enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350098"}
{"pmid": "4350099", "title": "Surgical treatment of amebic  liver abscess. Surgical treatment of hepatic  amebiasis.", "content": "Surgical treatment of amebic  liver abscess. Surgical treatment of hepatic  amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350099"}
{"pmid": "4350100", "title": "Calcifying mucinous adenocarcinoma of the gallbladder.", "content": "Calcifying mucinous adenocarcinoma of the gallbladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350100"}
{"pmid": "4350101", "title": "Aortic mitochondrial function in experimentally induced atherosclerosis in swine and rabbits.", "content": "Aortic mitochondrial function in experimentally induced atherosclerosis in swine and rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350101"}
{"pmid": "4350102", "title": "Interaction of a spin-labeled analog of acetyl coenzyme A with citrate synthase. Paramagnetic resonance and proton relaxation rate studies of binary and ternary complexes.", "content": "Interaction of a spin-labeled analog of acetyl coenzyme A with citrate synthase. Paramagnetic resonance and proton relaxation rate studies of binary and ternary complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350102"}
{"pmid": "4350103", "title": "Effect of insulin and growth hormone on rat liver cyclic nucleotide phosphodiesterase.", "content": "Effect of insulin and growth hormone on rat liver cyclic nucleotide phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350103"}
{"pmid": "4350104", "title": "Chemistry of the adenosine monophosphate site of rabbit muscle glycogen phosphorylase. II. Properties of 8-(m-(m-gluorosulfonylbenzamido) benzylthio)adenine-modified phosphorylase.", "content": "Chemistry of the adenosine monophosphate site of rabbit muscle glycogen phosphorylase. II. Properties of 8-(m-(m-gluorosulfonylbenzamido) benzylthio)adenine-modified phosphorylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350104"}
{"pmid": "4350105", "title": "Dilatometry biological membranes.", "content": "Dilatometry biological membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350105"}
{"pmid": "4350106", "title": "Structure of the lipid phase in cell envelope vesicles from Halobacterium cutirubrum.", "content": "Structure of the lipid phase in cell envelope vesicles from Halobacterium cutirubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350106"}
{"pmid": "4350107", "title": "Composition and structure of the O-specific side chain of endotoxin from Serratia marcescens 08.", "content": "Composition and structure of the O-specific side chain of endotoxin from Serratia marcescens 08.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350107"}
{"pmid": "4350108", "title": "Nuclear double-stranded ribonucleic acid of mammalian cells. Characteristics and biosynthesis.", "content": "Nuclear double-stranded ribonucleic acid of mammalian cells. Characteristics and biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350108"}
{"pmid": "4350109", "title": "A marker for medullary carcinoma of thyroid.", "content": "A marker for medullary carcinoma of thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350109"}
{"pmid": "4350110", "title": "Prospective study of cytomegalovirus infection in pregnancy.", "content": "Prospective study of cytomegalovirus infection in pregnancy. In a prospective study of cytomegalovirus infection in 1,040 pregnant women in London 319 (42%) of the white Englishwomen but only 28 (10%) of the immigrant Asian women were without antibodies at the onset of pregnancy. Out of 254 susceptible white women and 16 susceptible Asian women 8 (3%) and 3 (16%) respectively experienced primary infection during the course of pregnancy. The overall incidence of fetal infection after primary infection in the mother was almost 50%, and was higher in early pregnancy. One out of the five infected infants was found to be mentally retarded.Reactivation of latent infection was recognized in 0.7-2.9% of pregnant women; this occurred without involving the fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350110"}
{"pmid": "4350112", "title": "Serum alkaline phosphatase and rickets.", "content": "Serum alkaline phosphatase and rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350112"}
{"pmid": "4350111", "title": "Sarcoma after injection of intramuscular iron.", "content": "Sarcoma after injection of intramuscular iron. Two cases are presented of sarcomata arising at the site of previous iron dextran injections. One of the tumours showed a histological pattern associated with iron dextran administration in animal experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350111"}
{"pmid": "4350113", "title": "Immunological destruction in vitro of cytomegalovirus infected cells.", "content": "Immunological destruction in vitro of cytomegalovirus infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350113"}
{"pmid": "4350114", "title": "Care of the patient with inoperable lung cancer.", "content": "Care of the patient with inoperable lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350114"}
{"pmid": "4350119", "title": "Critical issues in psychiatry: a call for a reassessment of our nation's mental health care.", "content": "Critical issues in psychiatry: a call for a reassessment of our nation's mental health care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350119"}
{"pmid": "4350120", "title": "Consumer participation in mental health programs.", "content": "Consumer participation in mental health programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350120"}
{"pmid": "4350121", "title": "Action of miracil D and related compounds on DNA and RNA synthesis in regenerating liver and hepatomas.", "content": "Action of miracil D and related compounds on DNA and RNA synthesis in regenerating liver and hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350121"}
{"pmid": "4350122", "title": "Counteractions of the blocking of cell-mediated tumor immunity by inoculation of unblocking sera and splenectomy: immunotherapeutic effects on primary polyoma tumors in rats.", "content": "Counteractions of the blocking of cell-mediated tumor immunity by inoculation of unblocking sera and splenectomy: immunotherapeutic effects on primary polyoma tumors in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350122"}
{"pmid": "4350115", "title": "Dream recall: facts and perspectives.", "content": "Dream recall: facts and perspectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350115"}
{"pmid": "4350123", "title": "Antibodies to EB virus capsid antigen and to soluble antigen of lymphoblastoid cells in infectious mononucleosis patients.", "content": "Antibodies to EB virus capsid antigen and to soluble antigen of lymphoblastoid cells in infectious mononucleosis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350123"}
{"pmid": "4350124", "title": "Purification of antibodies to membrane antigens of hamster cells transformed by SV40 and binding of the radioiodinated, purified antibodies to intact cells.", "content": "Purification of antibodies to membrane antigens of hamster cells transformed by SV40 and binding of the radioiodinated, purified antibodies to intact cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350124"}
{"pmid": "4350126", "title": "SV40-induced transformation of cells of the lizard Gekko gecko.", "content": "SV40-induced transformation of cells of the lizard Gekko gecko.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350126"}
{"pmid": "4350125", "title": "Genetic stability of the sarcoma viruses in murine and avian sarcoma virus-transformed nonproducer cells.", "content": "Genetic stability of the sarcoma viruses in murine and avian sarcoma virus-transformed nonproducer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350125"}
{"pmid": "4350127", "title": "Effects of SV40 virus on the chromosomes of poikilothermic cells (Gekko gecko) cultivated at different temperatures.", "content": "Effects of SV40 virus on the chromosomes of poikilothermic cells (Gekko gecko) cultivated at different temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350127"}
{"pmid": "4350129", "title": "Radioimmunoassay of carcinoembryonic antigen in extracts of human colon and stomach.", "content": "Radioimmunoassay of carcinoembryonic antigen in extracts of human colon and stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350129"}
{"pmid": "4350130", "title": "The inducible alkaline phosphatase of rat heart: partial purification of the enzyme and its substrate specificity.", "content": "The inducible alkaline phosphatase of rat heart: partial purification of the enzyme and its substrate specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350130"}
{"pmid": "4350133", "title": "Plasma cortisol during normal glucose tolerance.", "content": "Plasma cortisol during normal glucose tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350133"}
{"pmid": "4350139", "title": "Hepatoma originated in the retroperitoneal space. Report of a case.", "content": "Hepatoma originated in the retroperitoneal space. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350139"}
{"pmid": "4350140", "title": "Fructose-1,6-diphosphatase in DMBA-induced rat mammary tumours.", "content": "Fructose-1,6-diphosphatase in DMBA-induced rat mammary tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350140"}
{"pmid": "4350141", "title": "Mixed tumors of the lower lip.", "content": "Mixed tumors of the lower lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350141"}
{"pmid": "4350136", "title": "Study of the interaction of  -glycerophosphate dehydrogenase and NAD-H by the methods of circular dichroism and fluorimetry.", "content": "Study of the interaction of  -glycerophosphate dehydrogenase and NAD-H by the methods of circular dichroism and fluorimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350136"}
{"pmid": "4350144", "title": "Primary gastric neoplasia in the dog: a clinico-pathological study.", "content": "Primary gastric neoplasia in the dog: a clinico-pathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350144"}
{"pmid": "4350143", "title": "Biochemical effects of 1,1-dichloroethylene in rats: dissociation of its hepatotoxicity from a lipoperoxidative mechanism.", "content": "Biochemical effects of 1,1-dichloroethylene in rats: dissociation of its hepatotoxicity from a lipoperoxidative mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350143"}
{"pmid": "4350137", "title": "Nature of the changes in the protein fluorescence of the mitochondria during a change in their functional state.", "content": "Nature of the changes in the protein fluorescence of the mitochondria during a change in their functional state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350137"}
{"pmid": "4350138", "title": "Biosynthesis of collagen in a chick embryo cell-free microsomal system.", "content": "Biosynthesis of collagen in a chick embryo cell-free microsomal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350138"}
{"pmid": "4350134", "title": "Study of the ability of a DNA polymerase mutant E. coli K12 pol A1 for elimination of single-stranded breaks in DNA caused by methyl methanesulfonate.", "content": "Study of the ability of a DNA polymerase mutant E. coli K12 pol A1 for elimination of single-stranded breaks in DNA caused by methyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350134"}
{"pmid": "4350148", "title": "Biological effects of Corynebacterium parvum. IV. Adjuvant and inhibitory activities on B lymphocytes.", "content": "Biological effects of Corynebacterium parvum. IV. Adjuvant and inhibitory activities on B lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350148"}
{"pmid": "4350147", "title": "The regeneration of skeletal muscle. A review.", "content": "The regeneration of skeletal muscle. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350147"}
{"pmid": "4350135", "title": "Investigation of the mechanism of spectral changes in carotenoids in the chromatophores of Rhodospirillum rubrum.", "content": "Investigation of the mechanism of spectral changes in carotenoids in the chromatophores of Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350135"}
{"pmid": "4350149", "title": "Gradient gel electrophoresis of human plasma lipoproteins.", "content": "Gradient gel electrophoresis of human plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350149"}
{"pmid": "4350150", "title": "A common error in measurements of 340 nm.", "content": "A common error in measurements of 340 nm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350150"}
{"pmid": "4350154", "title": "Oestrogen and oestrogen conjugate concentrations in late pregnancy plasma.", "content": "Oestrogen and oestrogen conjugate concentrations in late pregnancy plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350154"}
{"pmid": "4350155", "title": "The specificity of the estrogen receptor of human uterus.", "content": "The specificity of the estrogen receptor of human uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350155"}
{"pmid": "4350156", "title": "Testosterone \"receptors\" in purified nuclei of rat anterior hypophysis.", "content": "Testosterone \"receptors\" in purified nuclei of rat anterior hypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350156"}
{"pmid": "4350142", "title": "Correlations between mood, weight, and electrolytes during the menstrual cycle: a renin-angiotensin-aldosterone hypothesis of premenstrual tension.", "content": "Correlations between mood, weight, and electrolytes during the menstrual cycle: a renin-angiotensin-aldosterone hypothesis of premenstrual tension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350142"}
{"pmid": "4350161", "title": "Vasospasm in ischemic heart disease--a hypothesis.", "content": "Vasospasm in ischemic heart disease--a hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350161"}
{"pmid": "4350170", "title": "Contrasting effects of plastocyanin on the photoreduction and photooxidation of cytochrome f in chloroplasts.", "content": "Contrasting effects of plastocyanin on the photoreduction and photooxidation of cytochrome f in chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350170"}
{"pmid": "4350171", "title": "In vitro studies on yeast cytochrome c peroxidase and its possible function in the electron transfer and energy coupling reactions.", "content": "In vitro studies on yeast cytochrome c peroxidase and its possible function in the electron transfer and energy coupling reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350171"}
{"pmid": "4350172", "title": "Nitrogenase. 3. Nitrogenaseless mutants of Azotobacter vinelandii: activities, cross-reactions and EPR spectra.", "content": "Nitrogenase. 3. Nitrogenaseless mutants of Azotobacter vinelandii: activities, cross-reactions and EPR spectra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350172"}
{"pmid": "4350173", "title": "Electron transfer in cytochrome c: role of the polypeptide chain.", "content": "Electron transfer in cytochrome c: role of the polypeptide chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350173"}
{"pmid": "4350174", "title": "Nature of the activation of succinate dehydrogenase by various effectors and in hypobaria and hypoxia.", "content": "Nature of the activation of succinate dehydrogenase by various effectors and in hypobaria and hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350174"}
{"pmid": "4350175", "title": "Oxidative phosphorylation in mitochondria isolated from human fibroblasts.", "content": "Oxidative phosphorylation in mitochondria isolated from human fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350175"}
{"pmid": "4350176", "title": "Freeze-fracture studies on mitochondria from wild-type and respiratory-deficient yeasts.", "content": "Freeze-fracture studies on mitochondria from wild-type and respiratory-deficient yeasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350176"}
{"pmid": "4350179", "title": "Effect of adrenocorticotropin (ACTH) upon the drug response of intact and adrenalectomized rats.", "content": "Effect of adrenocorticotropin (ACTH) upon the drug response of intact and adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350179"}
{"pmid": "4350180", "title": "Sodium retention versus renin-angiotensin system in experimental renal hypertension.", "content": "Sodium retention versus renin-angiotensin system in experimental renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350180"}
{"pmid": "4350181", "title": "Electron microscopy in the diagnosis of pleural mesotheliomas.", "content": "Electron microscopy in the diagnosis of pleural mesotheliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350181"}
{"pmid": "4350182", "title": "Histology and ultrastructure of an oncocytic adenoma of the human pituitary.", "content": "Histology and ultrastructure of an oncocytic adenoma of the human pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350182"}
{"pmid": "4350183", "title": "Pathogenesis of Hodgkin's disease: separation and culture of different kinds of cells from Hodgkin's disease in a sterile isokinetic gradient of Ficoll in tissue culture medium.", "content": "Pathogenesis of Hodgkin's disease: separation and culture of different kinds of cells from Hodgkin's disease in a sterile isokinetic gradient of Ficoll in tissue culture medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350183"}
{"pmid": "4350184", "title": "Addison's disease secondary to metastatic carcinoma: an example of adrenocortical and adrenomedullary insuffiency.", "content": "Addison's disease secondary to metastatic carcinoma: an example of adrenocortical and adrenomedullary insuffiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350184"}
{"pmid": "4350185", "title": "Posterior hypothalamus and the regulation of body temperature.", "content": "Posterior hypothalamus and the regulation of body temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350185"}
{"pmid": "4350186", "title": "Embryonic antigen expression in chemically induced rat hepatomas and sarcomas.", "content": "Embryonic antigen expression in chemically induced rat hepatomas and sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350186"}
{"pmid": "4350187", "title": "Carcinoembryonic antigen (CEA) in gastrointestinal and extragastrointestinal tumors and its relationship to tumor-cell differentiation.", "content": "Carcinoembryonic antigen (CEA) in gastrointestinal and extragastrointestinal tumors and its relationship to tumor-cell differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350187"}
{"pmid": "4350188", "title": "The transformation of BHK 21 hamster cells by simian virus 40.", "content": "The transformation of BHK 21 hamster cells by simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350188"}
{"pmid": "4350178", "title": "Pigmented skin tumors.", "content": "Pigmented skin tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350178"}
{"pmid": "4350189", "title": "Variations in sarcoma and leukemia virus activity in somatic cell hybrids.", "content": "Variations in sarcoma and leukemia virus activity in somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350189"}
{"pmid": "4350191", "title": "The SV40 S antigen; a carcinoembryonic-type antigen of the hamster?", "content": "The SV40 S antigen; a carcinoembryonic-type antigen of the hamster?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350191"}
{"pmid": "4350192", "title": "Human cancer in households containing cats with malignant lymphoma.", "content": "Human cancer in households containing cats with malignant lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350192"}
{"pmid": "4350190", "title": "Australia antigen in Singapore Chinese patients with hepatocellular carcinoma and comparison groups: influence of technique sensitivity on differential frequencies.", "content": "Australia antigen in Singapore Chinese patients with hepatocellular carcinoma and comparison groups: influence of technique sensitivity on differential frequencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350190"}
{"pmid": "4350193", "title": "Feline malignant lymphoma: environmental factors and the occurrence of this viral cancer in cats.", "content": "Feline malignant lymphoma: environmental factors and the occurrence of this viral cancer in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350193"}
{"pmid": "4350194", "title": "Dietary aspects of hyperlipidemia.", "content": "Dietary aspects of hyperlipidemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350194"}
{"pmid": "4350195", "title": "Effect of certain biologic and antibacterial agents on development of acute respiratory tract disease in weaned beef calves.", "content": "Effect of certain biologic and antibacterial agents on development of acute respiratory tract disease in weaned beef calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350195"}
{"pmid": "4350197", "title": "Relationships between antimicrobial activities and chemically reactive functions in viomycin.", "content": "Relationships between antimicrobial activities and chemically reactive functions in viomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350197"}
{"pmid": "4350196", "title": "Chemical studies on tuberactinomycin. 3. The chemical structure of viomycin (tuberactinomycin B).", "content": "Chemical studies on tuberactinomycin. 3. The chemical structure of viomycin (tuberactinomycin B).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350196"}
{"pmid": "4350198", "title": "Cyclic AMP phosphodiesterase activity in the midgut of Manduca sexta.", "content": "Cyclic AMP phosphodiesterase activity in the midgut of Manduca sexta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350198"}
{"pmid": "4350202", "title": "Parasitization of the parasite.", "content": "Parasitization of the parasite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350202"}
{"pmid": "4350201", "title": "Single unit responses in the neospinothalamic system of the cat.", "content": "Single unit responses in the neospinothalamic system of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350201"}
{"pmid": "4350199", "title": "Effects of dietary manipulation on adipose tissue glycerokinase activity and plasma metabolite levels in the chicken (Gallus domesticus).", "content": "Effects of dietary manipulation on adipose tissue glycerokinase activity and plasma metabolite levels in the chicken (Gallus domesticus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350199"}
{"pmid": "4350200", "title": "Effects of blunted sympathetic nervous system response on regional tissue perfusion in experimental endotoxic shock.", "content": "Effects of blunted sympathetic nervous system response on regional tissue perfusion in experimental endotoxic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350200"}
{"pmid": "4350205", "title": "Central control of movement. VI. Strategies and tactics in research on central control of movement.", "content": "Central control of movement. VI. Strategies and tactics in research on central control of movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350205"}
{"pmid": "4350206", "title": "Central control of movement. IV. Control systems operating on spinal reflex mechanisms.", "content": "Central control of movement. IV. Control systems operating on spinal reflex mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350206"}
{"pmid": "4350210", "title": "Cranio-orbital resection and neck dissection for a recurrent mixed tumor of the lacrimal gland. Case report.", "content": "Cranio-orbital resection and neck dissection for a recurrent mixed tumor of the lacrimal gland. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350210"}
{"pmid": "4350213", "title": "Actomyosin-like protein in brain.", "content": "Actomyosin-like protein in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350213"}
{"pmid": "4350214", "title": "Epstein-Barr virus: detection of genome in somatic cell hybrids of Burkitt lymphoblastoid cells.", "content": "Epstein-Barr virus: detection of genome in somatic cell hybrids of Burkitt lymphoblastoid cells. Somatic cell hybrids of Burkitt lymphoblastoid cells, from which Epstein-Barr virus can be recovered, were examined for the presence of virus DNA by DNA-RNA hybridization. Four clones of hybrid cells, each negative for virus antigens by immunofluorescence, contained virus DNA in varying genomic equivalents. The number of virus genome equivalents increased in the hybrid cells after induction of virus with iododeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350214"}
{"pmid": "4350215", "title": "The metabolism in vivo 4,16-androstadien-3-one in man. Occurrence of 16-dehydro C 19  steroids, androstane-3,16,17-triols and other metabolites in urine.", "content": "The metabolism in vivo 4,16-androstadien-3-one in man. Occurrence of 16-dehydro C 19  steroids, androstane-3,16,17-triols and other metabolites in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350215"}
{"pmid": "4350216", "title": "Isolation and identification of 16alpha, 18-dihydroxydeoxycorticosterone from human adrenal gland incubations.", "content": "Isolation and identification of 16alpha, 18-dihydroxydeoxycorticosterone from human adrenal gland incubations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350216"}
{"pmid": "4350217", "title": "The occurrence and subcellular localization of 3 -hydroxysteroid dehydrogenase in adult rat brain.", "content": "The occurrence and subcellular localization of 3 -hydroxysteroid dehydrogenase in adult rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350217"}
{"pmid": "4350219", "title": "Adenovirus type 12 surface antigen detected by immunofluorescence in infected KB cells.", "content": "Adenovirus type 12 surface antigen detected by immunofluorescence in infected KB cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350219"}
{"pmid": "4350220", "title": "Transcriptive functions of Sendai firus nucleocapsid in infected cells.", "content": "Transcriptive functions of Sendai firus nucleocapsid in infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350220"}
{"pmid": "4350221", "title": "Interaction of genes controlling resistance to RSV(RAV-O).", "content": "Interaction of genes controlling resistance to RSV(RAV-O).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350221"}
{"pmid": "4350222", "title": "Properties of an SV40 transformed African green monkey kidney (BSC-1) cell line: interactions between SV40 and cellular DNA metabolism.", "content": "Properties of an SV40 transformed African green monkey kidney (BSC-1) cell line: interactions between SV40 and cellular DNA metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350222"}
{"pmid": "4350223", "title": "The identification of the circular forms of SV40 DNA in whole infected cell preparations.", "content": "The identification of the circular forms of SV40 DNA in whole infected cell preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350223"}
{"pmid": "4350224", "title": "Effects of 2-deoxy-D-glucose on herpes simplex virus replication.", "content": "Effects of 2-deoxy-D-glucose on herpes simplex virus replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350224"}
{"pmid": "4350225", "title": "Effect of actinomycin D on potato virus X multiplication in Datura stramonium leaves.", "content": "Effect of actinomycin D on potato virus X multiplication in Datura stramonium leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350225"}
{"pmid": "4350226", "title": "Isolation of the structural polypeptides of foot-and-mouth disease virus and analysis of their C-terminal sequences.", "content": "Isolation of the structural polypeptides of foot-and-mouth disease virus and analysis of their C-terminal sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350226"}
{"pmid": "4350227", "title": "A temperature-sensitive mutant of simian virus 40 affecting transforming ability.", "content": "A temperature-sensitive mutant of simian virus 40 affecting transforming ability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350227"}
{"pmid": "4350228", "title": "Genetic recombinants and heterozygotes derived from endogenous and exogenous avian RNA tumor viruses.", "content": "Genetic recombinants and heterozygotes derived from endogenous and exogenous avian RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350228"}
{"pmid": "4350229", "title": "Incorporation of 5-iodo-2'-deoxyuridine (IUdR) into SV40 DNA.", "content": "Incorporation of 5-iodo-2'-deoxyuridine (IUdR) into SV40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350229"}
{"pmid": "4350230", "title": "Control of group-specific antigen synthesis by the defective Gazdar murine sarcoma virus genome.", "content": "Control of group-specific antigen synthesis by the defective Gazdar murine sarcoma virus genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350230"}
{"pmid": "4350232", "title": "Base specific methylase activity in RNA tumor viruses: avian leukosis virion-associated RNA methylase(s).", "content": "Base specific methylase activity in RNA tumor viruses: avian leukosis virion-associated RNA methylase(s).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350232"}
{"pmid": "4350231", "title": "Iodination of vesicular stomatitis virus with lactoperoxidase.", "content": "Iodination of vesicular stomatitis virus with lactoperoxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350231"}
{"pmid": "4350245", "title": "Cooperative onset of a different state of water in the presence of macromolecules.", "content": "Cooperative onset of a different state of water in the presence of macromolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350245"}
{"pmid": "4350246", "title": "An oxygen magnetic resonance study of water in frog skeletal muscle.", "content": "An oxygen magnetic resonance study of water in frog skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350246"}
{"pmid": "4350244", "title": "Laboratory calibration of a technique for determination of respirable quartz in mine air.", "content": "Laboratory calibration of a technique for determination of respirable quartz in mine air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350244"}
{"pmid": "4350247", "title": "Supramolecular biology: a solid state physical approach to ion and electron transport.", "content": "Supramolecular biology: a solid state physical approach to ion and electron transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350247"}
{"pmid": "4350248", "title": "Implications of diffusion coefficient measurements for the structure of cellular water.", "content": "Implications of diffusion coefficient measurements for the structure of cellular water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350248"}
{"pmid": "4350249", "title": "The diffusion of water in striated muscle.", "content": "The diffusion of water in striated muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350249"}
{"pmid": "4350251", "title": "The oxidation of N,N'-bis(4-aminophenyl)-N,N'-dimethylethylenediamine (BED) by rat liver.", "content": "The oxidation of N,N'-bis(4-aminophenyl)-N,N'-dimethylethylenediamine (BED) by rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350251"}
{"pmid": "4350250", "title": "The effect of GTP hydrolysis by the peptide elongation enzymes on the sedimentation of ribosomes bearing peptidyl-tRNA and on the susceptibility of ribosome-bound tRNA to hydrolysis by  ribonuclease.", "content": "The effect of GTP hydrolysis by the peptide elongation enzymes on the sedimentation of ribosomes bearing peptidyl-tRNA and on the susceptibility of ribosome-bound tRNA to hydrolysis by  ribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350250"}
{"pmid": "4350252", "title": "Effect of substrate on the spin state of cytochrome P-450 in hepatic microsomes.", "content": "Effect of substrate on the spin state of cytochrome P-450 in hepatic microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350252"}
{"pmid": "4350253", "title": "The inactivation of lactoperoxidase and the acyl phosphatase activity of oxidized glyceraldehyde-3-phosphate dehydrogenase by phenlyhydrazine and phenyldiimide.", "content": "The inactivation of lactoperoxidase and the acyl phosphatase activity of oxidized glyceraldehyde-3-phosphate dehydrogenase by phenlyhydrazine and phenyldiimide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350253"}
{"pmid": "4350254", "title": "31 P and  13 C nmr measurements of a fructose-1-phosphate, Mn (II) and fructose 1,6-diphosphatase complex.", "content": "31 P and  13 C nmr measurements of a fructose-1-phosphate, Mn (II) and fructose 1,6-diphosphatase complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350254"}
{"pmid": "4350255", "title": "Hippocampal EEG and behavior: changes in amplitude and frequency of RSA (theta rhythm) associated with spontaneous and learned movement patterns in rats and cats.", "content": "Hippocampal EEG and behavior: changes in amplitude and frequency of RSA (theta rhythm) associated with spontaneous and learned movement patterns in rats and cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350255"}
{"pmid": "4350256", "title": "Incremental and decremental processes in Limulus ganglia: stimulus frequency and ganglion organization influences.", "content": "Incremental and decremental processes in Limulus ganglia: stimulus frequency and ganglion organization influences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350256"}
{"pmid": "4350257", "title": "Circular dichroism of cytochrome oxidase, cytochrome b 566 , and cytochrome c in beef heart mitochondrial membrane fragments.", "content": "Circular dichroism of cytochrome oxidase, cytochrome b 566 , and cytochrome c in beef heart mitochondrial membrane fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350257"}
{"pmid": "4350258", "title": "Cytochrome oxidase from Pseudomonas aeruginosa. I. Reaction with copper protein.", "content": "Cytochrome oxidase from Pseudomonas aeruginosa. I. Reaction with copper protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350258"}
{"pmid": "4350259", "title": "Iron protein content of Thiocapsapfennigii, a purple sulfur bacterium of atypical chlorophyll composition.", "content": "Iron protein content of Thiocapsapfennigii, a purple sulfur bacterium of atypical chlorophyll composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350259"}
{"pmid": "4350260", "title": "Primary events in the photosynthetic reaction centre from Rhodopseudomonas spheroides strain R26: triplet and oxidized states of bacteriochlorophyll and the identification of the primary electron acceptor.", "content": "Primary events in the photosynthetic reaction centre from Rhodopseudomonas spheroides strain R26: triplet and oxidized states of bacteriochlorophyll and the identification of the primary electron acceptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350260"}
{"pmid": "4350261", "title": "A peroxide-dependent reduction of cytochrome c by NADH.", "content": "A peroxide-dependent reduction of cytochrome c by NADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350261"}
{"pmid": "4350262", "title": "Hydrogen peroxide generating system in hog thyroid microsomes.", "content": "Hydrogen peroxide generating system in hog thyroid microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350262"}
{"pmid": "4350263", "title": "Studies on the metabolites of phylloquinone (vitamin K 1 ) in the urine of man.", "content": "Studies on the metabolites of phylloquinone (vitamin K 1 ) in the urine of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350263"}
{"pmid": "4350264", "title": "Adenylate cyclase activity in normal and leukemic human leukocytes as determined by a radioimmunoassay for cyclic AMP.", "content": "Adenylate cyclase activity in normal and leukemic human leukocytes as determined by a radioimmunoassay for cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350264"}
{"pmid": "4350265", "title": "Regulation of renal glycogen synthase. Interconversion of two forms in vitro.", "content": "Regulation of renal glycogen synthase. Interconversion of two forms in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350265"}
{"pmid": "4350266", "title": "Regulation of glycogen phosphorylase a phosphatase in Neurospora crassa.", "content": "Regulation of glycogen phosphorylase a phosphatase in Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350266"}
{"pmid": "4350267", "title": "Occurrence of a galactofuranose disaccharide in immunoadjuvant fractions of Mycobacterium tuberculosis (Cell walls and wax D).", "content": "Occurrence of a galactofuranose disaccharide in immunoadjuvant fractions of Mycobacterium tuberculosis (Cell walls and wax D).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350267"}
{"pmid": "4350268", "title": "Adenosine 3':5'-monophosphate-dependent and independent histone kinases isolated from human tonsillar lymphocytes.", "content": "Adenosine 3':5'-monophosphate-dependent and independent histone kinases isolated from human tonsillar lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350268"}
{"pmid": "4350270", "title": "Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: concentrations in Morris hepatomas of different growth rates.", "content": "Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: concentrations in Morris hepatomas of different growth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350270"}
{"pmid": "4350269", "title": "Inhibition of metabolic effects of growth hormone by various inhibitors of cyclic nucleotide phosphodiesterase.", "content": "Inhibition of metabolic effects of growth hormone by various inhibitors of cyclic nucleotide phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350269"}
{"pmid": "4350271", "title": "Firing patterns of Purkinje cells in the cat cerebellum for different maintained positions of the limbs.", "content": "Firing patterns of Purkinje cells in the cat cerebellum for different maintained positions of the limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350271"}
{"pmid": "4350272", "title": "Temporal sequence of cerebellar Purkinje and nuclear activity in relation to the acoustic startle  response.", "content": "Temporal sequence of cerebellar Purkinje and nuclear activity in relation to the acoustic startle  response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350272"}
{"pmid": "4350273", "title": "Attempted suicide: a description of the pre and post suicidal states.", "content": "Attempted suicide: a description of the pre and post suicidal states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350273"}
{"pmid": "4350275", "title": "Liberal telephone policy in treatment and aftercare helps reduce readmissions.", "content": "Liberal telephone policy in treatment and aftercare helps reduce readmissions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350275"}
{"pmid": "4350274", "title": "Baroreceptor activity in normotensive and hypertensive uremic patients.", "content": "Baroreceptor activity in normotensive and hypertensive uremic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350274"}
{"pmid": "4350276", "title": "Central response to infra-red stimulation of the pit receptors in a crotaline  snake, Trimeresurus flavoviridis.", "content": "Central response to infra-red stimulation of the pit receptors in a crotaline  snake, Trimeresurus flavoviridis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350276"}
{"pmid": "4350277", "title": "Integration of sensory and centrally programmed components in generation of cyclical feeding activity of Helisoma trivolvis.", "content": "Integration of sensory and centrally programmed components in generation of cyclical feeding activity of Helisoma trivolvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350277"}
{"pmid": "4350278", "title": "Color and spatial specificity of single units in Rhesus monkey foveal striate cortex.", "content": "Color and spatial specificity of single units in Rhesus monkey foveal striate cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350278"}
{"pmid": "4350281", "title": "Histamine and cyclic 3',5'-AMP in gastric acid secretion.", "content": "Histamine and cyclic 3',5'-AMP in gastric acid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350281"}
{"pmid": "4350282", "title": "Influence of cell-free ascites fluid and adenosine 3'5'-cyclic monophosphate upon the cell kinetics of Ehrlich's ascites carcinoma.", "content": "Influence of cell-free ascites fluid and adenosine 3'5'-cyclic monophosphate upon the cell kinetics of Ehrlich's ascites carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350282"}
{"pmid": "4350283", "title": "Oestrogen receptor binding is not restricted to target nuclei.", "content": "Oestrogen receptor binding is not restricted to target nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350283"}
{"pmid": "4350285", "title": "Thrombosthenin, the contractile protein of blood platelets. New facts and problems.", "content": "Thrombosthenin, the contractile protein of blood platelets. New facts and problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350285"}
{"pmid": "4350284", "title": "Epstein-Barr virus in human disease.", "content": "Epstein-Barr virus in human disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350284"}
{"pmid": "4350286", "title": "ESR study of a new anthraquinone glycoside.", "content": "ESR study of a new anthraquinone glycoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350286"}
{"pmid": "4350288", "title": "Psychiatry, through mental health to human services--what next?", "content": "Psychiatry, through mental health to human services--what next?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350288"}
{"pmid": "4350289", "title": "The planned obsolescence of psychiatric research.", "content": "The planned obsolescence of psychiatric research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350289"}
{"pmid": "4350290", "title": "Cellular biochemistry of narcotic analgesic drugs in the central nervous system of the rat.", "content": "Cellular biochemistry of narcotic analgesic drugs in the central nervous system of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350290"}
{"pmid": "4350296", "title": "Effect of cortisol on neuraminic acid concentration of normal and polyoma-transformed mouse cells in culture.", "content": "Effect of cortisol on neuraminic acid concentration of normal and polyoma-transformed mouse cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350296"}
{"pmid": "4350297", "title": "Bovine herpes mammillitis virus and vulvo-vaginitis.", "content": "Bovine herpes mammillitis virus and vulvo-vaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350297"}
{"pmid": "4350301", "title": "In vivo effect of adenosine 3',5'-monophosphate on Ehrlich ascites tumour cells.", "content": "In vivo effect of adenosine 3',5'-monophosphate on Ehrlich ascites tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350301"}
{"pmid": "4350302", "title": "Endocrine control of fetal lung development in the rabbit.", "content": "Endocrine control of fetal lung development in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350302"}
{"pmid": "4350303", "title": "Neurologic complications following lymphangiography. Possible mechanisms and a case of blindness.", "content": "Neurologic complications following lymphangiography. Possible mechanisms and a case of blindness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350303"}
{"pmid": "4350305", "title": "Pupillary inhibition of delay during Pavlovian conditioning of paralyzed cats.", "content": "Pupillary inhibition of delay during Pavlovian conditioning of paralyzed cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350305"}
{"pmid": "4350304", "title": "Reticular units: relations between responses to sensory stimulation and responses to neurohumors.", "content": "Reticular units: relations between responses to sensory stimulation and responses to neurohumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350304"}
{"pmid": "4350306", "title": "4'-Thioadenosine 3'5'-cyclic phosphate and derivatives. Chemical synthesis and hydrolysis by phosphodiesterase.", "content": "4'-Thioadenosine 3'5'-cyclic phosphate and derivatives. Chemical synthesis and hydrolysis by phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350306"}
{"pmid": "4350307", "title": "Biosynthesis of glutamate dehydrogenase in rat liver. Demonstration of its microsomal localization and hypothetical mechanism of transfer to mitochondria.", "content": "Biosynthesis of glutamate dehydrogenase in rat liver. Demonstration of its microsomal localization and hypothetical mechanism of transfer to mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350307"}
{"pmid": "4350308", "title": "The lactate dehydrogenase catalyzed reduction of pyruvate. Active substrate and substrate inhibition.", "content": "The lactate dehydrogenase catalyzed reduction of pyruvate. Active substrate and substrate inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350308"}
{"pmid": "4350309", "title": "The mechanism of polymyxin B action and selectivity toward biologic membranes.", "content": "The mechanism of polymyxin B action and selectivity toward biologic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350309"}
{"pmid": "4350310", "title": "Isolation and partial chemical characterization of cell-surface glycopeptides from AS-30D rat hepatoma which possess binding sites for wheat germ agglutinin and concanavalin A.", "content": "Isolation and partial chemical characterization of cell-surface glycopeptides from AS-30D rat hepatoma which possess binding sites for wheat germ agglutinin and concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350310"}
{"pmid": "4350311", "title": "Estrogen receptors in the rat uterus. Relationship between cytoplasmic and nuclear forms of the estrogen binding protein.", "content": "Estrogen receptors in the rat uterus. Relationship between cytoplasmic and nuclear forms of the estrogen binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350311"}
{"pmid": "4350313", "title": "Reaction of diethyl pyrocarbonate with nucleic acid components. Adenosine-containing nucleotides and dinucleoside phosphates.", "content": "Reaction of diethyl pyrocarbonate with nucleic acid components. Adenosine-containing nucleotides and dinucleoside phosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350313"}
{"pmid": "4350314", "title": "Role of silicon in diatom metabolism. II. Endogenous nucleoside triphosphate pools during silicic acid starvation of synchronized Cylindrotheca fusiformis.", "content": "Role of silicon in diatom metabolism. II. Endogenous nucleoside triphosphate pools during silicic acid starvation of synchronized Cylindrotheca fusiformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350314"}
{"pmid": "4350315", "title": "Role of silicon in diatom metabolism. 3. The effects of silicic acid on DNA polymerase, TMP kinase and DNA synthesis in Cylindrotheca fusiformis.", "content": "Role of silicon in diatom metabolism. 3. The effects of silicic acid on DNA polymerase, TMP kinase and DNA synthesis in Cylindrotheca fusiformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350315"}
{"pmid": "4350316", "title": "Fractionation of denatured bacterial DNA on methylate albumin kieselguhr columns. Is it strand separation?", "content": "Fractionation of denatured bacterial DNA on methylate albumin kieselguhr columns. Is it strand separation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350316"}
{"pmid": "4350317", "title": "The discharge from primary endings of muscle spindles during reflex activation of fusimotor neurones in the lightly anaesthetised and spinal cat.", "content": "The discharge from primary endings of muscle spindles during reflex activation of fusimotor neurones in the lightly anaesthetised and spinal cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350317"}
{"pmid": "4350318", "title": "Spinal and medullary reflex components of the somatosympathetic reflex discharges evoked by stimulation of the group IV somatic afferents.", "content": "Spinal and medullary reflex components of the somatosympathetic reflex discharges evoked by stimulation of the group IV somatic afferents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350318"}
{"pmid": "4350319", "title": "The adenosine 3',5'-monophosphate content of brain tissue obtained by an ultra-rapid freezing technique.", "content": "The adenosine 3',5'-monophosphate content of brain tissue obtained by an ultra-rapid freezing technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350319"}
{"pmid": "4350321", "title": "Development of binocular single units in the optic tectum of frogs raised with disparate stimulation to the eyes.", "content": "Development of binocular single units in the optic tectum of frogs raised with disparate stimulation to the eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350321"}
{"pmid": "4350320", "title": "Synaptic delay: its effect on information transmission in the crayfish caudal photoreceptor system.", "content": "Synaptic delay: its effect on information transmission in the crayfish caudal photoreceptor system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350320"}
{"pmid": "4350323", "title": "Sleep patterns related to rearing rats in enriched and impoverished environments.", "content": "Sleep patterns related to rearing rats in enriched and impoverished environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350323"}
{"pmid": "4350322", "title": "Excitatory and inhibitory inputs to single neurones in the solitary tract nucleus and adjacent reticular formation.", "content": "Excitatory and inhibitory inputs to single neurones in the solitary tract nucleus and adjacent reticular formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350322"}
{"pmid": "4350324", "title": "Effects of chlorpromazine on sleep in cats pretreated with para-chlorophenylalanine.", "content": "Effects of chlorpromazine on sleep in cats pretreated with para-chlorophenylalanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350324"}
{"pmid": "4350325", "title": "Responses of red nucleus neurones to cutaneous afferent inputs.", "content": "Responses of red nucleus neurones to cutaneous afferent inputs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350325"}
{"pmid": "4350326", "title": "Unit responses recorded from cervical spinal cord of awake monkey.", "content": "Unit responses recorded from cervical spinal cord of awake monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350326"}
{"pmid": "4350327", "title": "Habituation of the flexor reflex: inhibitory build-up or synaptic depression?", "content": "Habituation of the flexor reflex: inhibitory build-up or synaptic depression?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350327"}
{"pmid": "4350328", "title": "The joint peristimulus-time scatter diagram is an index of the operational significance of a synapse.", "content": "The joint peristimulus-time scatter diagram is an index of the operational significance of a synapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350328"}
{"pmid": "4350330", "title": "Convulsant actions of penicillin: effects on inhibitory mechanisms.", "content": "Convulsant actions of penicillin: effects on inhibitory mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350330"}
{"pmid": "4350329", "title": "Action of penicillin on inhibitory processes in the cat's cortex.", "content": "Action of penicillin on inhibitory processes in the cat's cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350329"}
{"pmid": "4350331", "title": "Metastatic mammary carcinoma in the eyelid with histiocytoid appearance.", "content": "Metastatic mammary carcinoma in the eyelid with histiocytoid appearance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350331"}
{"pmid": "4350332", "title": "Lateral inhibition in ambylopia: VER and metacontrast.", "content": "Lateral inhibition in ambylopia: VER and metacontrast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350332"}
{"pmid": "4350333", "title": "Centrifugal effects on the cat electroretinogram after section of one optic nerve.", "content": "Centrifugal effects on the cat electroretinogram after section of one optic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350333"}
{"pmid": "4350336", "title": "Personal styles of program implementors: a case study in community mental health failure.", "content": "Personal styles of program implementors: a case study in community mental health failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350336"}
{"pmid": "4350337", "title": "Will success spoil mental health care?", "content": "Will success spoil mental health care?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350337"}
{"pmid": "4350338", "title": "Pathology of the adventitial dermis. Anatomic observations and biologic speculations.", "content": "Pathology of the adventitial dermis. Anatomic observations and biologic speculations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350338"}
{"pmid": "4350339", "title": "The synovitis of acute gouty arthritis. A light and electron microscopic study.", "content": "The synovitis of acute gouty arthritis. A light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350339"}
{"pmid": "4350340", "title": "Florid subareolar duct papillomatosis (nipple adenoma) and mammary carcinoma: report of three cases.", "content": "Florid subareolar duct papillomatosis (nipple adenoma) and mammary carcinoma: report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350340"}
{"pmid": "4350341", "title": "Interference and two-tone inhibition.", "content": "Interference and two-tone inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350341"}
{"pmid": "4350343", "title": "Stimulation by cyclic adenosine monophosphate of plasmid deoxyribonucleic acid replication and catabolite repression of the plasmid deoxyribonucleic acid-protein relaxation complex.", "content": "Stimulation by cyclic adenosine monophosphate of plasmid deoxyribonucleic acid replication and catabolite repression of the plasmid deoxyribonucleic acid-protein relaxation complex. Colicinogenic factors ColE1 and ColE2 are bacterial plasmids that exist in Escherichia coli as supercoiled deoxyribonucleic acid (DNA) and as strand-specific, relaxation complexes of supercoiled DNA and protein. Newly replicated ColE1 DNA becomes complexed with protein after the replication event. This association of DNA and protein can take place under conditions in which DNA or protein synthesis is arrested. The addition of cyclic adenosine monophosphate (c-AMP) to normal cells growing in glucose medium results in a six- to tenfold stimulation in the rate of synthesis of the protein component(s) of the complex and a three- to fivefold stimulation in the rate of ColE1 DNA replication. Employing mutants deficient in catabolite gene activator protein or adenylate cyclase, it was shown that synthesis of both the plasmid-determined protein colicin E1 and the protein component(s) of the ColE1 relaxation complex is mediated through the c-AMP-catabolite gene activator protein system. Addition of c-AMP to ColE2-containing cells results in the stimulation of synthesis of ColE2 DNA and relaxation protein(s) as well as in the production of a protein component of the ColE2 relaxation complex that renders it sensitive to induced relaxation by heat treatment. In the case of ColE2, synthesis of the relaxation protein(s) is not dependent upon catabolite gene activator protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350343"}
{"pmid": "4350345", "title": "A paracrystalline inclusion formed during sporulation of enterotoxin-producing strains of Clostridium perfringens type A.", "content": "A paracrystalline inclusion formed during sporulation of enterotoxin-producing strains of Clostridium perfringens type A. A large paracrystalline inclusion is formed by certain strains of Clostridium perfringens type A during spore morphogenesis. In most cell thin sections, the inclusion appeared rod-shaped when sectioned at an angle perpendicular to its longer axis, and circular or oval-shaped when sectioned at an angle parallel to its longer axis. Measurements performed on electron micrographs of inclusions sectioned to reveal the rod shape indicated a fairly consistent thickness (width) of 192 +/- 23 nm. The length of the inclusions varied considerably with a maximum of approximately 2,120 nm being observed. Ultrastructurally, the inclusion was composed of closely packed, periodically spaced, parallel layers. Usually a single inclusion was randomly located in the cytoplasm of the cell. Two inclusions per cell were rarely observed. The inclusion was formed only by ent(+) strains of C. perfringens. Mutants of the ent(+) strain NCTC 8798 that were altered in their sporulating and enterotoxin-producing capacities and revertants of these mutants were tested for inclusion formation. The results indicate that, as with the ent(+) trait, a direct relationship exists between inclusion formation and spore formation. The synthesis of enterotoxin, formation of a morphologically distinct inclusion, and the initial deposition of discontinuous coat fragments around the forespore appear to be events closely related in time during spore morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350345"}
{"pmid": "4350344", "title": "Cyclic adenosine monophosphate-independent mutants of the lactose operon of Escherichia coli.", "content": "Cyclic adenosine monophosphate-independent mutants of the lactose operon of Escherichia coli. In Escherichia coli the transcription of the lactose operon, like other catabolite-sensitive operons, requires catabolite gene activator protein and 3',5'-cyclic adenosine monophosphate in addition to ribonucleic acid polymerase. We isolated and analyzed lac(+) revertants from a crp(-) strain of E. coli. We found that revertants with a higher level of expression only for the lac operon lie in the lac promoter region. These promoter mutations have no effect on operator or repressor function. Two of the revertants in which the lesions have been more precisely mapped carry mutations in the operator proximal segment of the promoter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350344"}
{"pmid": "4350342", "title": "Characterization of a cold-sensitive hisW mutant of Salmonella typhimurium.", "content": "Characterization of a cold-sensitive hisW mutant of Salmonella typhimurium. A cold-sensitive mutant of Salmonella typhimurium LT2 that grows at 37 C but not at 20 C has altered repression regulation in at least two amino acid biosynthetic pathways (histidine and isoleucine). The lesion conferring cold sensitivity that is linked with hisW is recessive. Assays for the acceptance of some amino acids by transfer ribonucleic acid (tRNA) reveal a decreased ability of the mutant tRNA to accept arginine, phenylalanine, and histidine. A mutation in a gene for tRNA maturation is a likely possibility for the mutation producing these effects on growth, regulation, and amino acid acceptance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350342"}
{"pmid": "4350348", "title": "ACTH and cortisol secretory patterns in man.", "content": "ACTH and cortisol secretory patterns in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350348"}
{"pmid": "4350349", "title": "Chorionic gonadotropin sensitive adenylate cyclase in human term placenta.", "content": "Chorionic gonadotropin sensitive adenylate cyclase in human term placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350349"}
{"pmid": "4350350", "title": "Studies on calciferol metabolism. VII. The renal production of the biologically active form of vitamin D, 1,25-dihydroxycholecalciferol; species, tissue and subcellular distribution.", "content": "Studies on calciferol metabolism. VII. The renal production of the biologically active form of vitamin D, 1,25-dihydroxycholecalciferol; species, tissue and subcellular distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350350"}
{"pmid": "4350352", "title": "Differential effect of cyclic adenosine monophosphate on the secretion of human placental lactogen and human chorionic gonadotropin.", "content": "Differential effect of cyclic adenosine monophosphate on the secretion of human placental lactogen and human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350352"}
{"pmid": "4350351", "title": "Endemic goiter prevention by iodized oil: a reassessment.", "content": "Endemic goiter prevention by iodized oil: a reassessment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350351"}
{"pmid": "4350353", "title": "The ascending fiber projections from the principal sensory trigeminal nucleus in the rat.", "content": "The ascending fiber projections from the principal sensory trigeminal nucleus in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350353"}
{"pmid": "4350354", "title": "Reciprocal point-to-point connections between parastriate and striate cortex in the squirrel monkey (Saimiri).", "content": "Reciprocal point-to-point connections between parastriate and striate cortex in the squirrel monkey (Saimiri).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350354"}
{"pmid": "4350355", "title": "Injection of ACTH induces recovery from shuttle-box avoidance deficits in rats with amygdaloid lesions.", "content": "Injection of ACTH induces recovery from shuttle-box avoidance deficits in rats with amygdaloid lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350355"}
{"pmid": "4350357", "title": "Changes in polarization of central branches of myelinated mechanoreceptor and nociceptor fibers during noxious and innocuous stimulation of the skin.", "content": "Changes in polarization of central branches of myelinated mechanoreceptor and nociceptor fibers during noxious and innocuous stimulation of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350357"}
{"pmid": "4350356", "title": "Correlations of neuronal spike discharges produced by monosynaptic connections and by common inputs.", "content": "Correlations of neuronal spike discharges produced by monosynaptic connections and by common inputs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350356"}
{"pmid": "4350358", "title": "Convergence of cutaneous and preoptic region thermal afferents on posterior hypothalamic neurons.", "content": "Convergence of cutaneous and preoptic region thermal afferents on posterior hypothalamic neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350358"}
{"pmid": "4350359", "title": "Distributed neuronal oscillators and efference copy in the feeding system of Pleurobranchaea.", "content": "Distributed neuronal oscillators and efference copy in the feeding system of Pleurobranchaea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350359"}
{"pmid": "4350361", "title": "Physiology of vision in the mollusk Lima scabra.", "content": "Physiology of vision in the mollusk Lima scabra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350361"}
{"pmid": "4350360", "title": "Peripheral somatic activation of neurons in the cat red nucleus.", "content": "Peripheral somatic activation of neurons in the cat red nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350360"}
{"pmid": "4350368", "title": "Virus-induced transformation without cell division.", "content": "Virus-induced transformation without cell division. Interference with the cell cycle by vinblastine sulfate immediately after cells were infected with Rous sarcoma virus had little effect on the a development of two metabolic changes that occur in transformed cells. These results, along with an earlier demonstration of morphological changes developing in infected nondividing cells, demonstrate that the phenotypic development of the malignant state can occur without the intervention of cell divisions after infection by Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350368"}
{"pmid": "4350366", "title": "On the use of psychiatric diagnosis for comparing psychiatric populations.", "content": "On the use of psychiatric diagnosis for comparing psychiatric populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350366"}
{"pmid": "4350367", "title": "Evaluation of community psychiatric practice.", "content": "Evaluation of community psychiatric practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350367"}
{"pmid": "4350365", "title": "Electrical transmission between symmetrical neurons in leech ganglia.", "content": "Electrical transmission between symmetrical neurons in leech ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350365"}
{"pmid": "4350364", "title": "Cerebellar unit responses to repetitive stimulation of somatic nerves.", "content": "Cerebellar unit responses to repetitive stimulation of somatic nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350364"}
{"pmid": "4350380", "title": "An evaluation of immunological indicators for amebic disease prevalence.", "content": "An evaluation of immunological indicators for amebic disease prevalence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350380"}
{"pmid": "4350383", "title": "Mucinous (adenocystic) carcinoma of the eyelid.", "content": "Mucinous (adenocystic) carcinoma of the eyelid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350383"}
{"pmid": "4350384", "title": "Studies of SV 40 DNA. V. Conversion of circular to linear SV 40 DNA by restriction endonuclease from Escherichia coli B.", "content": "Studies of SV 40 DNA. V. Conversion of circular to linear SV 40 DNA by restriction endonuclease from Escherichia coli B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350384"}
{"pmid": "4350385", "title": "The identification of different structural classes of nucleic acids by electrophoresis in polyacrylamide gels of different concentration.", "content": "The identification of different structural classes of nucleic acids by electrophoresis in polyacrylamide gels of different concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350385"}
{"pmid": "4350386", "title": "In vivo and in vitro effects of thyrotropin on ribosomal pattern of dog thyroid.", "content": "In vivo and in vitro effects of thyrotropin on ribosomal pattern of dog thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350386"}
{"pmid": "4350387", "title": "The primary electron acceptor of photosystem. I.", "content": "The primary electron acceptor of photosystem. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350387"}
{"pmid": "4350388", "title": "Biosynthesis of mitochondrial enzymes.", "content": "Biosynthesis of mitochondrial enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350388"}
{"pmid": "4350390", "title": "Conversion of angiotensin I into angiotensin II in the isolated perfused rat kidney.", "content": "Conversion of angiotensin I into angiotensin II in the isolated perfused rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350390"}
{"pmid": "4350389", "title": "Lipoproteins in relation to skin disease.", "content": "Lipoproteins in relation to skin disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350389"}
{"pmid": "4350391", "title": "Structure of normal and pathological lipoproteins.", "content": "Structure of normal and pathological lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350391"}
{"pmid": "4350393", "title": "Carbohydrate metabolism of larval Schistosoma mansoni.", "content": "Carbohydrate metabolism of larval Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350393"}
{"pmid": "4350394", "title": "The intranuclear bodies of Entamoeba.", "content": "The intranuclear bodies of Entamoeba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350394"}
{"pmid": "4350392", "title": "Beta lipoprotein protein turnover: an approach to the understanding of drug and disease mechanisms.", "content": "Beta lipoprotein protein turnover: an approach to the understanding of drug and disease mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350392"}
{"pmid": "4350395", "title": "The surface active lysosome of Entamoeba histolytica.", "content": "The surface active lysosome of Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350395"}
{"pmid": "4350397", "title": "The estimation of human renin-substrate concentration by radioimmunoassay of angiotensin I.", "content": "The estimation of human renin-substrate concentration by radioimmunoassay of angiotensin I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350397"}
{"pmid": "4350398", "title": "Steroid hormones and their receptors.", "content": "Steroid hormones and their receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350398"}
{"pmid": "4350396", "title": "Action of prostaglandin E 2  and of luteinizing hormone on ovarian adenylate cyclase, protein kinase and ornithine decarboxylase activity during postnatal development and maturity in the rat.", "content": "Action of prostaglandin E 2  and of luteinizing hormone on ovarian adenylate cyclase, protein kinase and ornithine decarboxylase activity during postnatal development and maturity in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350396"}
{"pmid": "4350399", "title": "The regulation of intestinal calcium transport by vitamin D.", "content": "The regulation of intestinal calcium transport by vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350399"}
{"pmid": "4350400", "title": "Subcutaneous growth of human tumours in mice.", "content": "Subcutaneous growth of human tumours in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350400"}
{"pmid": "4350403", "title": "Macrophage nonimmunologic recognition: target cell factors related to contact inhibition.", "content": "Macrophage nonimmunologic recognition: target cell factors related to contact inhibition. Activated mouse macrophages were not cytotoxic to contact-inhibited nontumorigenic 3T3 fibroblasts, but caused marked destruction to non-contact-inhibited, tumorigenic 3T12 and simian virus 40-transformed fibroblasts. Nonimmunologic recognition and destruction of target cells by activated macrophages is independent of altered morphology, abnormal karyotype, and ability for continuous multiplication in vitro-all characteristics of 3T3 fibroblasts. A modification e f the target cell surface that results in a high in vitro saturation density, agglutinability by plant lectins, and tumorigenicity appears to evoke a cytotoxic response by activated macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350403"}
{"pmid": "4350404", "title": "Thyrotropin and cyclic nucleotide effects on prostaglandin levels in isolated thyroid cells.", "content": "Thyrotropin and cyclic nucleotide effects on prostaglandin levels in isolated thyroid cells. Thyrotropin increases prostaglandin levels in isolated thyroid cells. Since comparable results were obtained with butyrated cyclic adenosine monophosphate derivatives as well as with the phosphodiesterase inhibitors quazodine and theophylline, it appears that cyclic adenosine monophosphate mediates this effect of thyrotropin. These observations suggest that intracellular prostaglandins play a role in modulating thyrotropin action on thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350404"}
{"pmid": "4350405", "title": "Radioreceptor assay for prolactin and other lactogenic hormones.", "content": "Radioreceptor assay for prolactin and other lactogenic hormones. A radioreceptor assay with a sensitivity of 5 nanograms per milliliter has been developed for mammalian and avian pituitary prolactin, placental lactogenic hormones, and humnan growth hormone, using a membrane receptor preparation isolated from rabbit mammary glands. Prolactin preparations inhibited the binding of [(125)I]prolactin to receptors in direct proportion to the biological potency of these preparations. Thus, the radioreceptor assay provides a convenient and simnple assay for hormones which have lactogenic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350405"}
{"pmid": "4350406", "title": "Effects of deep-sea pressures on microbial enzyme systems.", "content": "Effects of deep-sea pressures on microbial enzyme systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350406"}
{"pmid": "4350408", "title": "Chlorphentermine-induced ultrastructural alterations in foetal tissues.", "content": "Chlorphentermine-induced ultrastructural alterations in foetal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350408"}
{"pmid": "4350409", "title": "Morphometry of dog liver: normal base-line data.", "content": "Morphometry of dog liver: normal base-line data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350409"}
{"pmid": "4350410", "title": "Genesis of foam cells: study in rats after administration of Cloforex.", "content": "Genesis of foam cells: study in rats after administration of Cloforex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350410"}
{"pmid": "4350411", "title": "Participation of monocytes in transient glomerular hypercellularity in poststreptococcal glomerulonephritis.", "content": "Participation of monocytes in transient glomerular hypercellularity in poststreptococcal glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350411"}
{"pmid": "4350412", "title": "In vitro assembly of polioviruses. 3. Assembly of 14 S particles into empty capsids by poliovirus-infected HeLa cell membranes.", "content": "In vitro assembly of polioviruses. 3. Assembly of 14 S particles into empty capsids by poliovirus-infected HeLa cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350412"}
{"pmid": "4350413", "title": "HeLa cell nucleolar RNA synthesis after poliovirus infection.", "content": "HeLa cell nucleolar RNA synthesis after poliovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350413"}
{"pmid": "4350414", "title": "Temperature-sensitive avian sarcoma viruses: a physiological comparison of twenty mutants.", "content": "Temperature-sensitive avian sarcoma viruses: a physiological comparison of twenty mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350414"}
{"pmid": "4350415", "title": "Integration of viral into chromosomal deoxyribonucleic acid in an inducible line of polyoma-transformed cells.", "content": "Integration of viral into chromosomal deoxyribonucleic acid in an inducible line of polyoma-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350415"}
{"pmid": "4350416", "title": "Appearance of virus-specific RNA, virus particles, and cell surface changes in cells rapidly transformed by the murine sarcoma virus.", "content": "Appearance of virus-specific RNA, virus particles, and cell surface changes in cells rapidly transformed by the murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350416"}
{"pmid": "4350417", "title": "Measurement of endogenous leukosis virus nucleotide sequences in the DNA of normal avian embryos by RNA-DNA hybridization.", "content": "Measurement of endogenous leukosis virus nucleotide sequences in the DNA of normal avian embryos by RNA-DNA hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350417"}
{"pmid": "4350419", "title": "On neural inhibition, contrast effects and visual sensitivity.", "content": "On neural inhibition, contrast effects and visual sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350419"}
{"pmid": "4350418", "title": "Comparison of oligonucleotides produced by RNase T1 digestion of 7 S RNA from avian and murine oncornaviruses and from uninfected cells.", "content": "Comparison of oligonucleotides produced by RNase T1 digestion of 7 S RNA from avian and murine oncornaviruses and from uninfected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350418"}
{"pmid": "4350420", "title": "Chemodectoma with distant metastasis: case report and review of the literature.", "content": "Chemodectoma with distant metastasis: case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350420"}
{"pmid": "4350422", "title": "Experimental study of interactions between pneumoconiosis and mycobacterial infections.", "content": "Experimental study of interactions between pneumoconiosis and mycobacterial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350422"}
{"pmid": "4350421", "title": "The other side of marihuana research.", "content": "The other side of marihuana research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350421"}
{"pmid": "4350423", "title": "The role of quartz in the development of coal workers' pneumoconiosis.", "content": "The role of quartz in the development of coal workers' pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350423"}
{"pmid": "4350424", "title": "Inhalation studies of coal-quartz dust mixture.", "content": "Inhalation studies of coal-quartz dust mixture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350424"}
{"pmid": "4350425", "title": "The pulmonary response to coal dust.", "content": "The pulmonary response to coal dust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350425"}
{"pmid": "4350426", "title": "Antagonistic factors in the pathogenesis of coal workers' pneumoconiosis.", "content": "Antagonistic factors in the pathogenesis of coal workers' pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350426"}
{"pmid": "4350427", "title": "Prevalence of coal workers' pneumoconiosis in Yugoslavia.", "content": "Prevalence of coal workers' pneumoconiosis in Yugoslavia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350427"}
{"pmid": "4350429", "title": "Factors influencing dust retention in the pulmonary parenchyma.", "content": "Factors influencing dust retention in the pulmonary parenchyma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350429"}
{"pmid": "4350428", "title": "Coal workers' pneumoconiosis in South Africa.", "content": "Coal workers' pneumoconiosis in South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350428"}
{"pmid": "4350431", "title": "Relation of lung dust content to radiological changes in coal workers.", "content": "Relation of lung dust content to radiological changes in coal workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350431"}
{"pmid": "4350430", "title": "Types of fibrosis in coal workers' pneumoconiosis.", "content": "Types of fibrosis in coal workers' pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350430"}
{"pmid": "4350432", "title": "Roentgen pathological correlations in coal workers' pneumoconiosis.", "content": "Roentgen pathological correlations in coal workers' pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350432"}
{"pmid": "4350433", "title": "Validation of classifications of pneumoconiosis.", "content": "Validation of classifications of pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350433"}
{"pmid": "4350435", "title": "Sampling and evaluating respirable coal mine dust.", "content": "Sampling and evaluating respirable coal mine dust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350435"}
{"pmid": "4350434", "title": "Treatment of pneumoconiosis caused by coal-quartz dusts with polyvinylpyridine-N-oxide (P 204).", "content": "Treatment of pneumoconiosis caused by coal-quartz dusts with polyvinylpyridine-N-oxide (P 204).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350434"}
{"pmid": "4350436", "title": "Perspectives in current research for control of airborne dust in coal mines.", "content": "Perspectives in current research for control of airborne dust in coal mines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350436"}
{"pmid": "4350437", "title": "Recent advances in the analysis of respirable coal dust for free silica, trace elements, and organic constituents.", "content": "Recent advances in the analysis of respirable coal dust for free silica, trace elements, and organic constituents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350437"}
{"pmid": "4350438", "title": "Investigative techniques in the laboratory study of coal workers' pneumoconiosis: recent advances at the cellular level.", "content": "Investigative techniques in the laboratory study of coal workers' pneumoconiosis: recent advances at the cellular level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350438"}
{"pmid": "4350440", "title": "The physiology of renin.", "content": "The physiology of renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350440"}
{"pmid": "4350441", "title": "Liver-cell carcinoma presenting as bile-duct tumour.", "content": "Liver-cell carcinoma presenting as bile-duct tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350441"}
{"pmid": "4350442", "title": "Glomus jugulare tumours--radiotherapy or surgery?", "content": "Glomus jugulare tumours--radiotherapy or surgery?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350442"}
{"pmid": "4350443", "title": "Multiple renal silica calculi.", "content": "Multiple renal silica calculi. Investigation of a patient with a history of renal colic, who had taken the equivalent of 2 g magnesium trisilicate after every meal for many years, showed that he was forming silica calculi. The nature of the stone was diagnosed only after quantitative analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350443"}
{"pmid": "4350444", "title": "The denatured states of lysozyme.", "content": "The denatured states of lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350444"}
{"pmid": "4350445", "title": "Comparative study of the development of alkaline phosphodiesterase I and alkaline phosphatase in mucosa of rat jejunum and ileum.", "content": "Comparative study of the development of alkaline phosphodiesterase I and alkaline phosphatase in mucosa of rat jejunum and ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350445"}
{"pmid": "4350447", "title": "Thymidine as one of the factors in a beef liver extract decreasing  3 H-thymidine incorporation into DNA.", "content": "Thymidine as one of the factors in a beef liver extract decreasing  3 H-thymidine incorporation into DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350447"}
{"pmid": "4350446", "title": "Studies on glycogen metabolism in normal and diabetic rat heart in vivo.", "content": "Studies on glycogen metabolism in normal and diabetic rat heart in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350446"}
{"pmid": "4350450", "title": "Let us stay near our patients.", "content": "Let us stay near our patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350450"}
{"pmid": "4350448", "title": "Ribonucleic acid polymerase induced in L-cells infected with vesicular stomatitis virus.", "content": "Ribonucleic acid polymerase induced in L-cells infected with vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350448"}
{"pmid": "4350453", "title": "Ultrastructural and biochemical changes in the liver of monkeys given butylated hydroxytoluene and butylated hydroxyanisole.", "content": "Ultrastructural and biochemical changes in the liver of monkeys given butylated hydroxytoluene and butylated hydroxyanisole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350453"}
{"pmid": "4350455", "title": "Hypophysis and function of pancreatic islets. 3. Secretion and biosynthesis of insulin in isolated pancreatic islets of intact and hypophysectomized rats in the presence of growth hormone, corticotrophin and human chorionic somatotrophin in vitro.", "content": "Hypophysis and function of pancreatic islets. 3. Secretion and biosynthesis of insulin in isolated pancreatic islets of intact and hypophysectomized rats in the presence of growth hormone, corticotrophin and human chorionic somatotrophin in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350455"}
{"pmid": "4350454", "title": "Relative eye-injury potential of heavy-duty phosphate and non-phosphate laundry detergents.", "content": "Relative eye-injury potential of heavy-duty phosphate and non-phosphate laundry detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350454"}
{"pmid": "4350456", "title": "Fasting in obese females: plasma renin after glucose refeeding.", "content": "Fasting in obese females: plasma renin after glucose refeeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350456"}
{"pmid": "4350457", "title": "Thyroid hormone binding to the anterior pituitary gland.", "content": "Thyroid hormone binding to the anterior pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350457"}
{"pmid": "4350458", "title": "ACTH inhibition of dehydration-induced changes in the hypothalamic neurosecretory system of the musk shrew, suncus murinus L.", "content": "ACTH inhibition of dehydration-induced changes in the hypothalamic neurosecretory system of the musk shrew, suncus murinus L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350458"}
{"pmid": "4350459", "title": "Sero-epidemiology of cytomegalovirus infection in and around Chandigarh (Northern India).", "content": "Sero-epidemiology of cytomegalovirus infection in and around Chandigarh (Northern India).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350459"}
{"pmid": "4350460", "title": "The epidemiology of amoebiasis in an urban area.", "content": "The epidemiology of amoebiasis in an urban area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350460"}
{"pmid": "4350461", "title": "Direct amoebicidal action of known antiamoebic drugs against axenically grown Entamoeba histolytica.", "content": "Direct amoebicidal action of known antiamoebic drugs against axenically grown Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350461"}
{"pmid": "4350462", "title": "Adrenergic neurone blocking actions of procaine and lignocaine.", "content": "Adrenergic neurone blocking actions of procaine and lignocaine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350462"}
{"pmid": "4350466", "title": "Nondysenteric intestinal amebiasis. Treatment with diloxanide furoate.", "content": "Nondysenteric intestinal amebiasis. Treatment with diloxanide furoate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350466"}
{"pmid": "4350468", "title": "Effect of acute transection on the synthesis and turnover of 5-HT in the rat spinal cord.", "content": "Effect of acute transection on the synthesis and turnover of 5-HT in the rat spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350468"}
{"pmid": "4350467", "title": "Dibutyryl cyclic AMP and adrenaline increase contractile force and  45 Ca uptake in mammalian cardiac muscle.", "content": "Dibutyryl cyclic AMP and adrenaline increase contractile force and  45 Ca uptake in mammalian cardiac muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350467"}
{"pmid": "4350470", "title": "Effects on shock-elicited aggression in mice of preferentially protecting brain monoamines against the depleting action of reserpine.", "content": "Effects on shock-elicited aggression in mice of preferentially protecting brain monoamines against the depleting action of reserpine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350470"}
{"pmid": "4350469", "title": "Non-competitive and competitive inhibition of mixed function oxidase in rat liver microsomes by metyrapone.", "content": "Non-competitive and competitive inhibition of mixed function oxidase in rat liver microsomes by metyrapone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350469"}
{"pmid": "4350472", "title": "Effects of stress and REM sleep deprivation on the patterns of avoidance learning and brain acetylcholine in the mouse.", "content": "Effects of stress and REM sleep deprivation on the patterns of avoidance learning and brain acetylcholine in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350472"}
{"pmid": "4350473", "title": "Interaction of oxotremorine with atropine, chlorpromazine, cyproheptadine, imipramine and phenoxybenzamine on the flexor reflex of the chronic spinal dog.", "content": "Interaction of oxotremorine with atropine, chlorpromazine, cyproheptadine, imipramine and phenoxybenzamine on the flexor reflex of the chronic spinal dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350473"}
{"pmid": "4350474", "title": "Enzyme release from polymorphonuclear leukocyte lysosomes: regulation by autonomic drugs and cyclic nucleotides.", "content": "Enzyme release from polymorphonuclear leukocyte lysosomes: regulation by autonomic drugs and cyclic nucleotides. Osmotic release of beta-glucuronidase from polymorphonuclear leukocyte lysosomes is inhibited by catecholamines and adenosine 3',5'-monophosphate, and accelerated by cholinergic agents and guanosine 3',5'-monophosphate. These actions are specific for the sympathetic and parasympathetic neurotransmitters and for the two cyclic nucleotides, as phenylephrine, tyramine, choline, adenosine 5'-monophosphate and guanosine 5'-monophosphate do not inodify lysosomal enzyme release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350474"}
{"pmid": "4350478", "title": "Endothelial inclusions in congenital infantile nephrosis.", "content": "Endothelial inclusions in congenital infantile nephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350478"}
{"pmid": "4350479", "title": "Cellular autophagy and cell atrophy in the rat liver during long-term starvation. A quantitative morphological study with regard to diurnal variations.", "content": "Cellular autophagy and cell atrophy in the rat liver during long-term starvation. A quantitative morphological study with regard to diurnal variations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350479"}
{"pmid": "4350480", "title": "The development of cholangiofibrosis and hepatomas in galactosamine induced cirrhotic rat livers.", "content": "The development of cholangiofibrosis and hepatomas in galactosamine induced cirrhotic rat livers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350480"}
{"pmid": "4350482", "title": "The primary structure of tRNA trp  from brewer's yeast. I. Complete digestion with pancreatic ribonuclease and T 1  ribonuclease.", "content": "The primary structure of tRNA trp  from brewer's yeast. I. Complete digestion with pancreatic ribonuclease and T 1  ribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350482"}
{"pmid": "4350483", "title": "The primary structure of tryptophan transfer ribonucleic acid from brewer's yeast. II. Partial digestion with pancreatic ribonuclease and derivation of complete sequence.", "content": "The primary structure of tryptophan transfer ribonucleic acid from brewer's yeast. II. Partial digestion with pancreatic ribonuclease and derivation of complete sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350483"}
{"pmid": "4350484", "title": "Accessibility of Escherichia coli 5S RNA base residues to chemical reagents. Influence of chemical alterations on the affinity of 5S RNA for the 50S subunit structure.", "content": "Accessibility of Escherichia coli 5S RNA base residues to chemical reagents. Influence of chemical alterations on the affinity of 5S RNA for the 50S subunit structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350484"}
{"pmid": "4350485", "title": "In vivo studies of the possible role of cholesteryl esters as precursors of bile acids.", "content": "In vivo studies of the possible role of cholesteryl esters as precursors of bile acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350485"}
{"pmid": "4350488", "title": "Retinal embolism after hysterosalpingography.", "content": "Retinal embolism after hysterosalpingography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350488"}
{"pmid": "4350496", "title": "Ultrastructural observations on the calcification of human dental pulp.", "content": "Ultrastructural observations on the calcification of human dental pulp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350496"}
{"pmid": "4350497", "title": "Scanning electron microscopic observations on bone from patients with hypophosphataemic (vitamin D resistant) rickets.", "content": "Scanning electron microscopic observations on bone from patients with hypophosphataemic (vitamin D resistant) rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350497"}
{"pmid": "4350498", "title": "The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals.", "content": "The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350498"}
{"pmid": "4350499", "title": "Factors affecting the precipitation of calcium phosphate in vitro.", "content": "Factors affecting the precipitation of calcium phosphate in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350499"}
{"pmid": "4350501", "title": "The effects of bacterial collagenase in rabbit vitreous.", "content": "The effects of bacterial collagenase in rabbit vitreous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350501"}
{"pmid": "4350500", "title": "The swinging flashlight test in multiphasic screening for eye disease.", "content": "The swinging flashlight test in multiphasic screening for eye disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350500"}
{"pmid": "4350502", "title": "Preparation and specificity of antiserum to synthetic secretin and its use in a radioimmunoassay (RIA).", "content": "Preparation and specificity of antiserum to synthetic secretin and its use in a radioimmunoassay (RIA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350502"}
{"pmid": "4350503", "title": "Dissociation of gonadotropin-induced ovulation and steroidogenesis in immature rats.", "content": "Dissociation of gonadotropin-induced ovulation and steroidogenesis in immature rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350503"}
{"pmid": "4350504", "title": "Incorporation of orthophosphate 32Pi into the phospholipids of slices of gonads, anterior pituitary and liver of calf.", "content": "Incorporation of orthophosphate 32Pi into the phospholipids of slices of gonads, anterior pituitary and liver of calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350504"}
{"pmid": "4350505", "title": "Characteristics of the nuclear RNA polymerase from rat anterior pituitary tissue.", "content": "Characteristics of the nuclear RNA polymerase from rat anterior pituitary tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350505"}
{"pmid": "4350506", "title": "Amoebiasis in pediatric age group.", "content": "Amoebiasis in pediatric age group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350506"}
{"pmid": "4350508", "title": "Cellular reactions against Burkitt Lymphoma cells. I. Colony inhibition with effector cells from patients with Burkitt's lymphoma.", "content": "Cellular reactions against Burkitt Lymphoma cells. I. Colony inhibition with effector cells from patients with Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350508"}
{"pmid": "4350507", "title": "Compared action of a polyoma-virus-specific inhibitor on the formation of polyoma capsid antigen and of polyoma tumor antigen.", "content": "Compared action of a polyoma-virus-specific inhibitor on the formation of polyoma capsid antigen and of polyoma tumor antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350507"}
{"pmid": "4350509", "title": "Spontaneous appearance of cytopathology and rat C-type virus (WF-1) in a rat embryo cell line.", "content": "Spontaneous appearance of cytopathology and rat C-type virus (WF-1) in a rat embryo cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350509"}
{"pmid": "4350510", "title": "Studies on type-H virus-like particles in hamster: their role in oncogenesis.", "content": "Studies on type-H virus-like particles in hamster: their role in oncogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350510"}
{"pmid": "4350511", "title": "Cytomegalovirus infections in leukaemic children.", "content": "Cytomegalovirus infections in leukaemic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350511"}
{"pmid": "4350513", "title": "Cellular immunity in Wilm's tumour and neuroblastoma.", "content": "Cellular immunity in Wilm's tumour and neuroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350513"}
{"pmid": "4350514", "title": "The formation of variants with a reversion of properties of transformed cells. VII. Chromosome numbers and re-reversion in subtetraploid variants.", "content": "The formation of variants with a reversion of properties of transformed cells. VII. Chromosome numbers and re-reversion in subtetraploid variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350514"}
{"pmid": "4350515", "title": "Is the brain behind the eye? Implications of processing by the retina.", "content": "Is the brain behind the eye? Implications of processing by the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350515"}
{"pmid": "4350517", "title": "A varicella-like disease in macaque monkeys.", "content": "A varicella-like disease in macaque monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350517"}
{"pmid": "4350519", "title": "Failure to induce fetal infection by inoculation of pregnant immune heifers with bovine parainfluenza 3 virus.", "content": "Failure to induce fetal infection by inoculation of pregnant immune heifers with bovine parainfluenza 3 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350519"}
{"pmid": "4350518", "title": "Host defense mechanisms against herpes simplex virus. II. Protection conferred by sensitized spleen cells.", "content": "Host defense mechanisms against herpes simplex virus. II. Protection conferred by sensitized spleen cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350518"}
{"pmid": "4350520", "title": "Spontaneous Herpesvirus saimiri lymphoma in an owl monkey.", "content": "Spontaneous Herpesvirus saimiri lymphoma in an owl monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350520"}
{"pmid": "4350521", "title": "Incidence of antibody to envelope antigen of herpes simplex virus type 2 among patients with cervical carcinoma and matched controls.", "content": "Incidence of antibody to envelope antigen of herpes simplex virus type 2 among patients with cervical carcinoma and matched controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350521"}
{"pmid": "4350522", "title": "The effects of endogenous compounds on ovine myometrial contractility and adenyl cyclase system.", "content": "The effects of endogenous compounds on ovine myometrial contractility and adenyl cyclase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350522"}
{"pmid": "4350527", "title": "Transmission of rhinovirus colds by self-inoculation.", "content": "Transmission of rhinovirus colds by self-inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350527"}
{"pmid": "4350528", "title": "Inapparent congenital cytomegalovirus infection. A follow-up study.", "content": "Inapparent congenital cytomegalovirus infection. A follow-up study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350528"}
{"pmid": "4350529", "title": "Infant of the addicted mother.", "content": "Infant of the addicted mother.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350529"}
{"pmid": "4350530", "title": "Median-nerve neuropathy after percutaneous puncture of the brachial artery in patients receiving anticoagulants.", "content": "Median-nerve neuropathy after percutaneous puncture of the brachial artery in patients receiving anticoagulants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350530"}
{"pmid": "4350531", "title": "Congenital cytomegalovirus infection.", "content": "Congenital cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350531"}
{"pmid": "4350532", "title": "Isolation of human amnion cells transformed by rescuable murine sarcoma virus.", "content": "Isolation of human amnion cells transformed by rescuable murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350532"}
{"pmid": "4350535", "title": "Studies on the fine structure of the protozoan Cyclidium, with special reference to the mitochondria, pellicle and surface-associated bacteria.", "content": "Studies on the fine structure of the protozoan Cyclidium, with special reference to the mitochondria, pellicle and surface-associated bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350535"}
{"pmid": "4350537", "title": "[Ultrastructure of the dorsal giant fibre system in the ventral nerve cord of the earthworm. I. Somata of the giant fibres].", "content": "[Ultrastructure of the dorsal giant fibre system in the ventral nerve cord of the earthworm. I. Somata of the giant fibres].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350537"}
{"pmid": "4350539", "title": "The ultrastructure of the caecal epithelium of the intraredial cercaria of Neophasis lageniformis (Lebour, 1910) (Trematoda, Acanthocolpidae).", "content": "The ultrastructure of the caecal epithelium of the intraredial cercaria of Neophasis lageniformis (Lebour, 1910) (Trematoda, Acanthocolpidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350539"}
{"pmid": "4350540", "title": "The synaptic ribbons of the guinea-pig pineal gland under normal and experimental conditions.", "content": "The synaptic ribbons of the guinea-pig pineal gland under normal and experimental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350540"}
{"pmid": "4350542", "title": "Mortality, antibody development, and viral persistence in porcine fetuses incubated in utero with SMEDI (entero-) virus.", "content": "Mortality, antibody development, and viral persistence in porcine fetuses incubated in utero with SMEDI (entero-) virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350542"}
{"pmid": "4350541", "title": "Arrhenoblastoma: in vivo and in vitro studies.", "content": "Arrhenoblastoma: in vivo and in vitro studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350541"}
{"pmid": "4350543", "title": "Feline virus-induced tumors and the immune response: recent developments.", "content": "Feline virus-induced tumors and the immune response: recent developments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350543"}
{"pmid": "4350545", "title": "A simple method for obtaining undiluted nasal secretions from cattle.", "content": "A simple method for obtaining undiluted nasal secretions from cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350545"}
{"pmid": "4350544", "title": "Vaccination against Marek's disease: possible causes of failure of herpesvirus of turkeys (strain FC126) to protect chickens against Marek's disease.", "content": "Vaccination against Marek's disease: possible causes of failure of herpesvirus of turkeys (strain FC126) to protect chickens against Marek's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350544"}
{"pmid": "4350546", "title": "Abdominal-muscle rigidity induced by morphine and nitrous oxide.", "content": "Abdominal-muscle rigidity induced by morphine and nitrous oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350546"}
{"pmid": "4350549", "title": "The mitotic apparatus of a zygomycete, Phycomyces blakesleeanus.", "content": "The mitotic apparatus of a zygomycete, Phycomyces blakesleeanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350549"}
{"pmid": "4350551", "title": "Comparison of early injury to liver endoplasmic reticulum by halomethanes, hexachloroethane, benzene, toluene, bromobenzene, ethionine, thioacetamide and dimethylnitrosamine.", "content": "Comparison of early injury to liver endoplasmic reticulum by halomethanes, hexachloroethane, benzene, toluene, bromobenzene, ethionine, thioacetamide and dimethylnitrosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350551"}
{"pmid": "4350550", "title": "Cell wall composition and synthesis via Golgi-directed scale formation in the marine eucaryote, Schizochytrium aggregatum, with a note on Thraustochytrium sp.", "content": "Cell wall composition and synthesis via Golgi-directed scale formation in the marine eucaryote, Schizochytrium aggregatum, with a note on Thraustochytrium sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350550"}
{"pmid": "4350552", "title": "Effect of cyclic 3',5'-monophosphate on edema and granuloma induced by carrageenin.", "content": "Effect of cyclic 3',5'-monophosphate on edema and granuloma induced by carrageenin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350552"}
{"pmid": "4350553", "title": "Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizng enzyme system. II. Effect of enzyme kinetics and electron transport system.", "content": "Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizng enzyme system. II. Effect of enzyme kinetics and electron transport system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350553"}
{"pmid": "4350554", "title": "Inhibition of some mitochondrial functions by acrolein and methylvinylketone.", "content": "Inhibition of some mitochondrial functions by acrolein and methylvinylketone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350554"}
{"pmid": "4350555", "title": "Inhibition by cysteamine of steroid 11  -hydroxylation.", "content": "Inhibition by cysteamine of steroid 11  -hydroxylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350555"}
{"pmid": "4350556", "title": "Importance of the route of administration of ccl 4 in the protective effect of promethazine.", "content": "Importance of the route of administration of ccl 4 in the protective effect of promethazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350556"}
{"pmid": "4350557", "title": "Magnetic resonance studies on membrane and model membrane systems. 3. Fatty acid motions in aqueous lecithin dispersions.", "content": "Magnetic resonance studies on membrane and model membrane systems. 3. Fatty acid motions in aqueous lecithin dispersions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350557"}
{"pmid": "4350558", "title": "Effect of proteins on the motion of spin-labeled fatty acids in mycoplasma membranes.", "content": "Effect of proteins on the motion of spin-labeled fatty acids in mycoplasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350558"}
{"pmid": "4350559", "title": "Preparation of plasma membranes from isolated cells of newborn rat brain.", "content": "Preparation of plasma membranes from isolated cells of newborn rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350559"}
{"pmid": "4350560", "title": "Platelet dysfunction in glycogen storage disease type I.", "content": "Platelet dysfunction in glycogen storage disease type I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350560"}
{"pmid": "4350568", "title": "Neuroradiology of juxtasellar mass lesions.", "content": "Neuroradiology of juxtasellar mass lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350568"}
{"pmid": "4350567", "title": "Heterogeneity of acid phosphatase activity in human polymorphonuclear leukocytes.", "content": "Heterogeneity of acid phosphatase activity in human polymorphonuclear leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350567"}
{"pmid": "4350572", "title": "Communication for child mental health: 1973 NIMH information interchange.", "content": "Communication for child mental health: 1973 NIMH information interchange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350572"}
{"pmid": "4350573", "title": "The fate of mestranol (17 -ethynylestradiol-3-methyl ether) in the isolated perfused rat liver.", "content": "The fate of mestranol (17 -ethynylestradiol-3-methyl ether) in the isolated perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350573"}
{"pmid": "4350574", "title": "Effect of insulin on cerebral adenyl cyclase and phosphodiesterase.", "content": "Effect of insulin on cerebral adenyl cyclase and phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350574"}
{"pmid": "4350575", "title": "The influence of deamidation on the biological activity of porcine adrenocorticotropic hormone (ACTH).", "content": "The influence of deamidation on the biological activity of porcine adrenocorticotropic hormone (ACTH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350575"}
{"pmid": "4350576", "title": "Inhibitors of proteolysis and glucose uptake by diaphragm muscle in vitro under insulin action.", "content": "Inhibitors of proteolysis and glucose uptake by diaphragm muscle in vitro under insulin action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350576"}
{"pmid": "4350577", "title": "Further studies with precipitation in gel test in diagnosis of smallpox. I. Studies on detection of antibodies in sera by pig test.", "content": "Further studies with precipitation in gel test in diagnosis of smallpox. I. Studies on detection of antibodies in sera by pig test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350577"}
{"pmid": "4350578", "title": "Aflatoxin hepatic carcinogenesis: an experimental comparative study.", "content": "Aflatoxin hepatic carcinogenesis: an experimental comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350578"}
{"pmid": "4350579", "title": "Comparative drug trials in symptomatic and asymptomatic non-dysenteric amoebic colitis.", "content": "Comparative drug trials in symptomatic and asymptomatic non-dysenteric amoebic colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350579"}
{"pmid": "4350580", "title": "Minor salivary gland tumors: a survey of 64 cases.", "content": "Minor salivary gland tumors: a survey of 64 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350580"}
{"pmid": "4350581", "title": "Malignant mixed tumor of parotid gland with a solitary metastasis to the radius.", "content": "Malignant mixed tumor of parotid gland with a solitary metastasis to the radius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350581"}
{"pmid": "4350587", "title": "Aminoacyl-tRNA synthetase activity in virions of avian myeloblastosis virus.", "content": "Aminoacyl-tRNA synthetase activity in virions of avian myeloblastosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350587"}
{"pmid": "4350588", "title": "Transfer of the B77 virus genome from virogenic mammalian cells to other mammalian cells by cell fusion.", "content": "Transfer of the B77 virus genome from virogenic mammalian cells to other mammalian cells by cell fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350588"}
{"pmid": "4350589", "title": "Monoclonal macroglobulinemia and cytomegalic inclusion disease.", "content": "Monoclonal macroglobulinemia and cytomegalic inclusion disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350589"}
{"pmid": "4350590", "title": "Electron microscopic demonstration of adenovirus in appendix vermiformis in a case of ileocecal intussusception.", "content": "Electron microscopic demonstration of adenovirus in appendix vermiformis in a case of ileocecal intussusception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350590"}
{"pmid": "4350591", "title": "Cancer of the colon and disseminated intravascular coagulation.", "content": "Cancer of the colon and disseminated intravascular coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350591"}
{"pmid": "4350592", "title": "A sensitive cell culture system for the virus of porcine inclusion body rhinitis (cytomegalic inclusion disease).", "content": "A sensitive cell culture system for the virus of porcine inclusion body rhinitis (cytomegalic inclusion disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350592"}
{"pmid": "4350593", "title": "Tests in sheep of attenuated sheep pox vaccines.", "content": "Tests in sheep of attenuated sheep pox vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350593"}
{"pmid": "4350594", "title": "Factors associated with the production of attenuated sheep pox vaccines.", "content": "Factors associated with the production of attenuated sheep pox vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350594"}
{"pmid": "4350595", "title": "Antagonists of angiotensin. Effect on the blood pressure of normal and hypertensive rats.", "content": "Antagonists of angiotensin. Effect on the blood pressure of normal and hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350595"}
{"pmid": "4350596", "title": "Presence and stimulation of adenyl cyclase in pancreas homogenate.", "content": "Presence and stimulation of adenyl cyclase in pancreas homogenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350596"}
{"pmid": "4350607", "title": "Generalized cytomegalic inclusion disease presenting an infectious mononucleosis syndrome (so-called cytomegalovirus mononucleosis) in a previously healthy adult--an autopsy study.", "content": "Generalized cytomegalic inclusion disease presenting an infectious mononucleosis syndrome (so-called cytomegalovirus mononucleosis) in a previously healthy adult--an autopsy study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350607"}
{"pmid": "4350609", "title": "Pathological studies on viral pneumonia and interstitial pneumonitis caused by unknown etiology.", "content": "Pathological studies on viral pneumonia and interstitial pneumonitis caused by unknown etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350609"}
{"pmid": "4350608", "title": "Post-traumatic hypothalamic obesity--an autopsy case.", "content": "Post-traumatic hypothalamic obesity--an autopsy case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350608"}
{"pmid": "4350610", "title": "Role of the small intestine in cholesterol metabolism.", "content": "Role of the small intestine in cholesterol metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350610"}
{"pmid": "4350611", "title": "Lipoproteins and the relative importance of plasma cholesterol and triglycerides in peripheral arterial disease.", "content": "Lipoproteins and the relative importance of plasma cholesterol and triglycerides in peripheral arterial disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350611"}
{"pmid": "4350614", "title": "CNS: afferent mechanisms with emphasis on physiological and behavioral correlations.", "content": "CNS: afferent mechanisms with emphasis on physiological and behavioral correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350614"}
{"pmid": "4350616", "title": "Hypothalamic control of adenohypophysial secretions.", "content": "Hypothalamic control of adenohypophysial secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350616"}
{"pmid": "4350615", "title": "Biochemical physiology of central synapses.", "content": "Biochemical physiology of central synapses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350615"}
{"pmid": "4350618", "title": "Wakefulness and feeding in human newborns.", "content": "Wakefulness and feeding in human newborns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350618"}
{"pmid": "4350617", "title": "Repeated oral ingestion of 5-hydroxytryptophan. The effect on behavior and sleep processes in two schizophrenic children.", "content": "Repeated oral ingestion of 5-hydroxytryptophan. The effect on behavior and sleep processes in two schizophrenic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350617"}
{"pmid": "4350612", "title": "Indetification and characterization of pulmonary dust burden in pneumoconiosis.", "content": "Indetification and characterization of pulmonary dust burden in pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350612"}
{"pmid": "4350621", "title": "Biochemical studies of liver tumors of children.", "content": "Biochemical studies of liver tumors of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350621"}
{"pmid": "4350613", "title": "Separation of plasma lipids by thin-layer chromatography.", "content": "Separation of plasma lipids by thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350613"}
{"pmid": "4350623", "title": "Congenital mesoblastic nephroma and its recurrence.", "content": "Congenital mesoblastic nephroma and its recurrence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350623"}
{"pmid": "4350622", "title": "Hexachlorobenzene and rat liver.", "content": "Hexachlorobenzene and rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350622"}
{"pmid": "4350624", "title": "Grouped muscle action potential area.", "content": "Grouped muscle action potential area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350624"}
{"pmid": "4350625", "title": "Peripheral nerve damage resulting from local hemorrhage and ischemia.", "content": "Peripheral nerve damage resulting from local hemorrhage and ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350625"}
{"pmid": "4350629", "title": "Rat mammary gland nuclear RNA polymerases in late pregnancy and lactation.", "content": "Rat mammary gland nuclear RNA polymerases in late pregnancy and lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350629"}
{"pmid": "4350630", "title": "Interaction of 6-thioguanylic acid homologues with ribonuclease T 1 . Spectrophotometric and gel filtration studies.", "content": "Interaction of 6-thioguanylic acid homologues with ribonuclease T 1 . Spectrophotometric and gel filtration studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350630"}
{"pmid": "4350631", "title": "Degradation of ribosomal RNA during chicken lens development.", "content": "Degradation of ribosomal RNA during chicken lens development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350631"}
{"pmid": "4350633", "title": "Lack of significant visible C-type virus activation in the bone marrow and thymus of mice given a leukaemogenic dose of methylnitrosourea.", "content": "Lack of significant visible C-type virus activation in the bone marrow and thymus of mice given a leukaemogenic dose of methylnitrosourea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350633"}
{"pmid": "4350636", "title": "Tracheotomy in infants and children.", "content": "Tracheotomy in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350636"}
{"pmid": "4350627", "title": "Antibodies to viral and synthetic double-stranded RNA in discoid lupus erythematosus.", "content": "Antibodies to viral and synthetic double-stranded RNA in discoid lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350627"}
{"pmid": "4350626", "title": "Fine structural analysis of rabbit synovial cells. I. The normal synovium and changes in organ culture.", "content": "Fine structural analysis of rabbit synovial cells. I. The normal synovium and changes in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350626"}
{"pmid": "4350641", "title": "Effects of ethanol on afferent transmission in the central visual pathway of cats.", "content": "Effects of ethanol on afferent transmission in the central visual pathway of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350641"}
{"pmid": "4350642", "title": "Partial reduction of ferricytochrome c by cyanide mediated by disulphide compounds.", "content": "Partial reduction of ferricytochrome c by cyanide mediated by disulphide compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350642"}
{"pmid": "4350643", "title": "Iron binding in human liver ferritin.", "content": "Iron binding in human liver ferritin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350643"}
{"pmid": "4350644", "title": "Origin of the milk fat globule.", "content": "Origin of the milk fat globule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350644"}
{"pmid": "4350645", "title": "The requirement of membrane sialic acid in the stimulation of phagocytosis by the natural tetrapeptide, tuftsin.", "content": "The requirement of membrane sialic acid in the stimulation of phagocytosis by the natural tetrapeptide, tuftsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350645"}
{"pmid": "4350647", "title": "The role of acidic phospholipids in glucagon action on rat liver adenylate cyclase.", "content": "The role of acidic phospholipids in glucagon action on rat liver adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350647"}
{"pmid": "4350646", "title": "Hormonal regulation of adipocyte enzymes. The effects of epinephrine and insulin on the control of lipase, phosphorylase kinase, phosphorylase, and glycogen synthase.", "content": "Hormonal regulation of adipocyte enzymes. The effects of epinephrine and insulin on the control of lipase, phosphorylase kinase, phosphorylase, and glycogen synthase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350646"}
{"pmid": "4350648", "title": "Glucocorticoid receptors in lung. I. Specific binding of glucocorticoids to cytoplasmic components of rabbit fetal lung.", "content": "Glucocorticoid receptors in lung. I. Specific binding of glucocorticoids to cytoplasmic components of rabbit fetal lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350648"}
{"pmid": "4350649", "title": "The enzymatic cleavage of 5'-triphosphate termini from ribonucleic acid polymerase products.", "content": "The enzymatic cleavage of 5'-triphosphate termini from ribonucleic acid polymerase products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350649"}
{"pmid": "4350650", "title": "The structure of oxidized cytochrome c 2  of Rhodospirillum rubrum.", "content": "The structure of oxidized cytochrome c 2  of Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350650"}
{"pmid": "4350651", "title": "Complex formation between bacitracin peptides and isoprenyl pyrophosphates. The specificity of lipid-peptide interactions.", "content": "Complex formation between bacitracin peptides and isoprenyl pyrophosphates. The specificity of lipid-peptide interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350651"}
{"pmid": "4350652", "title": "Studies on enzymes involved in the catabolism of phospholipids in Escherichia coli.", "content": "Studies on enzymes involved in the catabolism of phospholipids in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350652"}
{"pmid": "4350653", "title": "Studies on rat liver phenylalanyl transfer ribonucleic acid synthetase. II. Further purification, substrate specificity, and effects of substrates on heat inactivation.", "content": "Studies on rat liver phenylalanyl transfer ribonucleic acid synthetase. II. Further purification, substrate specificity, and effects of substrates on heat inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350653"}
{"pmid": "4350655", "title": "Novel phosphoglucans from the cytoplasm of Phytophthora palmivora and their selective occurrence in certain life cycle stages.", "content": "Novel phosphoglucans from the cytoplasm of Phytophthora palmivora and their selective occurrence in certain life cycle stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350655"}
{"pmid": "4350654", "title": "Purification and properties of Ascaris cytochrome b 560.", "content": "Purification and properties of Ascaris cytochrome b 560.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350654"}
{"pmid": "4350656", "title": "Leukocytic response to adrenocorticotrophic hormone as influenced by the infectious history of the mammary gland.", "content": "Leukocytic response to adrenocorticotrophic hormone as influenced by the infectious history of the mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350656"}
{"pmid": "4350657", "title": "Effects of stress on serum zinc and plasma corticoids in dairy cattle.", "content": "Effects of stress on serum zinc and plasma corticoids in dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350657"}
{"pmid": "4350658", "title": "Reduction of iodine transfer to milk of cows after perchlorate ingestion.", "content": "Reduction of iodine transfer to milk of cows after perchlorate ingestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350658"}
{"pmid": "4350659", "title": "Primary pulmonary neoplasms in beagle dogs exposed to aerosols of  144 Ce in fused-clay particles.", "content": "Primary pulmonary neoplasms in beagle dogs exposed to aerosols of  144 Ce in fused-clay particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350659"}
{"pmid": "4350661", "title": "Correlation between tumor invasiveness and content of A-type particles in Ehrlich ascites tumor: a model of quantitative electron microscopy.", "content": "Correlation between tumor invasiveness and content of A-type particles in Ehrlich ascites tumor: a model of quantitative electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350661"}
{"pmid": "4350660", "title": "Epidemiology of cancer of the pancreas.", "content": "Epidemiology of cancer of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350660"}
{"pmid": "4350662", "title": "Mammary tumor virus (MTV) infection of CBA/Bln mice involving production of antibodies to MTV.", "content": "Mammary tumor virus (MTV) infection of CBA/Bln mice involving production of antibodies to MTV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350662"}
{"pmid": "4350663", "title": "Spontaneous tumors of aging wild house mice. Incidence, pathology, and C-type virus expression.", "content": "Spontaneous tumors of aging wild house mice. Incidence, pathology, and C-type virus expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350663"}
{"pmid": "4350664", "title": "Histoproliferative effect of Rauscher leukemia virus on lymphatic tissue. IV. Lactic dehydrogenase virus and erythropoietin potentiation of the eythroid response.", "content": "Histoproliferative effect of Rauscher leukemia virus on lymphatic tissue. IV. Lactic dehydrogenase virus and erythropoietin potentiation of the eythroid response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350664"}
{"pmid": "4350665", "title": "Increased oncogenicity and synthesis of herpesvirus antigens in hamster cells exposed to herpes simplex type-2 virus.", "content": "Increased oncogenicity and synthesis of herpesvirus antigens in hamster cells exposed to herpes simplex type-2 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350665"}
{"pmid": "4350666", "title": "Oncogenicity of plaque variants of CELO virus in newborn hamsters.", "content": "Oncogenicity of plaque variants of CELO virus in newborn hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350666"}
{"pmid": "4350667", "title": "Suppression of growth of P-815 mastocytoma cells in vitro by drugs increasing cellular cyclic 3',5'-adenosine monophosphate.", "content": "Suppression of growth of P-815 mastocytoma cells in vitro by drugs increasing cellular cyclic 3',5'-adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350667"}
{"pmid": "4350668", "title": "Soluble and membrane-bound adenylate cyclase activity in Yoshida ascites hepatoma.", "content": "Soluble and membrane-bound adenylate cyclase activity in Yoshida ascites hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350668"}
{"pmid": "4350669", "title": "Ketone body oxidation by mouse hepatoma BW7756.", "content": "Ketone body oxidation by mouse hepatoma BW7756.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350669"}
{"pmid": "4350676", "title": "Detailed hormonal studies during and after pregnancy in a previously hypophysectomized patient.", "content": "Detailed hormonal studies during and after pregnancy in a previously hypophysectomized patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350676"}
{"pmid": "4350677", "title": "Corticotrophin-releasing factor activity in hypothalamic extracts of man.", "content": "Corticotrophin-releasing factor activity in hypothalamic extracts of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350677"}
{"pmid": "4350678", "title": "Iodide perchlorate discharge test in lithium-treated patients.", "content": "Iodide perchlorate discharge test in lithium-treated patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350678"}
{"pmid": "4350679", "title": "Bioassay of calcitonin by determinations of blood calcium-45 levels in rats and mice.", "content": "Bioassay of calcitonin by determinations of blood calcium-45 levels in rats and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350679"}
{"pmid": "4350680", "title": "Remitting signs in cerebral mass lesions.", "content": "Remitting signs in cerebral mass lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350680"}
{"pmid": "4350681", "title": "Studies in children with impetigo. Bacteriology, serology, and incidence of glomerulonephritis.", "content": "Studies in children with impetigo. Bacteriology, serology, and incidence of glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350681"}
{"pmid": "4350682", "title": "Guillain-Barré syndrome. Occurrence following combined mumps-rubella vaccine.", "content": "Guillain-Barré syndrome. Occurrence following combined mumps-rubella vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350682"}
{"pmid": "4350683", "title": "Hereditary recurrent brachial neuropathy.", "content": "Hereditary recurrent brachial neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350683"}
{"pmid": "4350687", "title": "Decrease in HCG--binding capacity of target tissues influenced by hypophysectomy.", "content": "Decrease in HCG--binding capacity of target tissues influenced by hypophysectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350687"}
{"pmid": "4350688", "title": "Vascular damage and lipid peroxidation in choline-deficient rats.", "content": "Vascular damage and lipid peroxidation in choline-deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350688"}
{"pmid": "4350689", "title": "The phosphorylases system of the cardiac muscle of normal and reserpinized rats poisoned with 2,4-dinitrophenol.", "content": "The phosphorylases system of the cardiac muscle of normal and reserpinized rats poisoned with 2,4-dinitrophenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350689"}
{"pmid": "4350690", "title": "Alterations in lipid metabolism following trauma in rabbits.", "content": "Alterations in lipid metabolism following trauma in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350690"}
{"pmid": "4350691", "title": "Distribution of a renin-like enzyme in the bovine adrenal gland.", "content": "Distribution of a renin-like enzyme in the bovine adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350691"}
{"pmid": "4350694", "title": "pH-dependent nuclear magnetic resonance spectra of  15 N-enriched glycine. Line shape and relaxation studies.", "content": "pH-dependent nuclear magnetic resonance spectra of  15 N-enriched glycine. Line shape and relaxation studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350694"}
{"pmid": "4350692", "title": "The reaction of Ca ++ with the inner and outer membrane of mitochondria.", "content": "The reaction of Ca ++ with the inner and outer membrane of mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350692"}
{"pmid": "4350695", "title": "Crystal and molecular structure of the salt (1-methylnicotinamide)(+) aden-9-ylacetate(-) dihydrate. A model for the intramolecular interactions of oxidized nicotinamide adenine dinucleotide.", "content": "Crystal and molecular structure of the salt (1-methylnicotinamide)(+) aden-9-ylacetate(-) dihydrate. A model for the intramolecular interactions of oxidized nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350695"}
{"pmid": "4350696", "title": "Synthesis of 6'-cyano-6'-deoxyhomoadenosine-6'-phosphonic acid and its phosphoryl and pyrophosphoryl anhydrides and studies of their interactions with adenine nucleotide utilizing enzymes.", "content": "Synthesis of 6'-cyano-6'-deoxyhomoadenosine-6'-phosphonic acid and its phosphoryl and pyrophosphoryl anhydrides and studies of their interactions with adenine nucleotide utilizing enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350696"}
{"pmid": "4350697", "title": "Antibody affinity chromatography of hog and bovine spleen DNase II.", "content": "Antibody affinity chromatography of hog and bovine spleen DNase II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350697"}
{"pmid": "4350698", "title": "Analysis of corticosteroids in mixtures by gradient elution liquid chromatography.", "content": "Analysis of corticosteroids in mixtures by gradient elution liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350698"}
{"pmid": "4350700", "title": "The action of streptolysin S on mouse-liver mitochondria.", "content": "The action of streptolysin S on mouse-liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350700"}
{"pmid": "4350699", "title": "Differential responses of crab neuromuscular synapses to cesium ion.", "content": "Differential responses of crab neuromuscular synapses to cesium ion. Excitatory postsynaptic potentials (EPSP's) generated in crab muscle fibers by a single motor axon, differ in amplitude and facilitation. Some EPSP's are large at low frequencies of stimulation and show little facilitation; others are smaller and show pronounced facilitation. When K(+) is replaced by Cs(+) in the physiological solution, all EPSP's increase in amplitude, but small EPSP's increase proportionately more than large ones. Quantal content of transmission, determined by external recording at single synaptic regions, undergoes a much larger increase at facilitating synapses. The increase in quantal content of transmission is attributable to prolongation of the nerve terminal action potential in Cs(+). After 1-2 h of Cs(+) treatment, defacilitation of synaptic potentials occurs at synapses which initially showed facilitation. This indicates that Cs(+) treatment drastically increases the fraction of the \"immediately available\" transmitter store released by each nerve impulse, especially at terminals with facilitating synapses. It is proposed that facilitating synapses normally release less of the \"immediately available\" store of transmitter than poorly facilitating synapses. Possible reasons for this difference in performance are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350699"}
{"pmid": "4350701", "title": "Prevalence of cytomagalovirus antibodies in the population of Northern Greece.", "content": "Prevalence of cytomagalovirus antibodies in the population of Northern Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350701"}
{"pmid": "4350702", "title": "Functional changes in motoneurones of hemiparetic patients.", "content": "Functional changes in motoneurones of hemiparetic patients. Forty-six patients have been studied after upper motor neurone lesions of cerebrovascular origin. The numbers of functioning motor units in extensor digitorum brevis muscles were reduced to approximately half between the second and sixth months after a hemiplegic episode. The surviving motor units tended to have slow twitches and appeared to increase their sizes after the lesions had been present for about 20 months. The findings are explained on the basis of transsynaptic changes in alpha-motoneurones after degeneration of corticospinal fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350702"}
{"pmid": "4350703", "title": "Neuromuscular block after intra-arterially injected acetylcholine. 1. Introduction, methods, and technique.", "content": "Neuromuscular block after intra-arterially injected acetylcholine. 1. Introduction, methods, and technique. The neuromuscular depolarizing block induced by intra-arterially injected ACh was studied to determine the variability in the same subject and in different subjects without disorders at the motor end-plate. Amplitude of action potentials of the opponens pollicis muscle evoked by intermittent repetitive supramaximal stimulation of the median nerve at the wrist were recorded for one hour from the beginning of ACh injection. The features of prompt and late depression stages after the injection were analysed statistically. Re-testing of the same subjects after a while shows that, in spite of all efforts to maintain the same experimental conditions, variations do occur in late depression. Time course and duration are particularly affected, while the degree of depression is altered but slightly. The presence of such variations limits this test to evaluation of the influence of other factors only within their already established statistical limits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350703"}
{"pmid": "4350704", "title": "Neuromuscular block after intra-arterially injected acetylcholine. 2. Effects of ACTH treatments as possible detectors of desensitization level in the receptor site.", "content": "Neuromuscular block after intra-arterially injected acetylcholine. 2. Effects of ACTH treatments as possible detectors of desensitization level in the receptor site. It has been suggested that the effect of ACTH in myasthenia gravis may be ascribed to an action involving neuromuscular transmission which favours repolarization processes, with a tendency towards hyperpolarization of the membranes of muscle fibres and motor nerve endings. A similar mechanism has been postulated for the action of ACTH in epilepsy (Klein, 1970). A direct or indirect action on nerve membrane would interfere with depolarization. There is evidence of raised concentration of intracellular potassium and increased outflow of sodium ions which would cause hyperpolarization of the membrane. This paper studies the effect of ACTH on the late block of neuromuscular transmission caused by acetylcholine (ACTH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350704"}
{"pmid": "4350705", "title": "Recruitment order of motor units in man: significance of pre-existing state of facilitation.", "content": "Recruitment order of motor units in man: significance of pre-existing state of facilitation. It has been shown in previous investigations that the recruitment order of motor units is different in tonic and in phasic voluntary activity. The significance of the pre-existing state of facilitation in the motoneurone pool for the recruitment of units is studied, using the phasic flexion reflex in the anterior tibial muscle as test reflex. It is shown that the recruitment order of units in a series of reflexes (1) is unstable if the subject does not expect the stimulus; (2) is stable and identical with that in tonic activity if the subject subliminally facilitates the motoneurone pool before the reflex activation; (3) is stable and almost identical with that in tonic activity if the subject expects the stimulus and therefore involuntarily influences the motoneurone pool; (4) is stable and similar to that in phasic voluntary activity if the subject inhibits the motoneurone pool before the activation and the stimulus strength thus consequentially is increased; and (5) is influenced by blockade of the proprioceptive afferent impulses from the muscle. It is concluded that normal man can select in advance the recruitment order of motor units most appropriate for the work intended.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350705"}
{"pmid": "4350706", "title": "Post-ischaemic paraesthesiae in diabetes mellitus.", "content": "Post-ischaemic paraesthesiae in diabetes mellitus. A quantitative assessment of post-ischaemic paraesthesiae has been made in 50 diabetic subjects and in a group of healthy age-matched controls. The results show a highly significant diminution of the paraesthetic response in the diabetic subjects. The degree of depression of the paraesthetic response was associated with the duration of the disease and the severity of the metabolic abnormality as determined by the degree of insulin dependence. Diabetics with the juvenile onset type of the disease were more adversely affected than those with the maturity onset type. There was no consistent relationship between the degree of depression of the paraesthesiae and the presence of peripheral neuropathy. The significance of these results is discussed in relation to the factors which determine the composition of the ionic micro-environment of myelinated nerve and the level of electrical excitability of the nerve fibre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350706"}
{"pmid": "4350707", "title": "Molecular weight determination of Sendai RNA by dimethyl sulfoxide gradient sedimentation.", "content": "Molecular weight determination of Sendai RNA by dimethyl sulfoxide gradient sedimentation. The molecular weight of the large RNA of Sendai virus has been determined by sedimentation analysis in sucrose gradients containing 99% dimethyl sulfoxide (DMSO) to be 2.3 x 10(6). Sendai RNA recovered from 99% DMSO was found to cosediment with nondenatured Sendai RNA at 46 to 48s in ordinary sucrose gradients. The molecular weight value of 2.3 x 10(6) is considerably smaller than the estimates of 6 x 10(6) to 7 x 10(6) determined under nondenaturing conditions, suggesting a unique structure for Sendai RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350707"}
{"pmid": "4350708", "title": "Growth of coliphage T7 in Salmonella typhimurium.", "content": "Growth of coliphage T7 in Salmonella typhimurium. A mutant of Salmonella typhimurium was found to be sensitive to killing by coliphage T7 because of an alteration in its surface properties. However, the infections were abortive and studies with (32)P-labeled T7 grown in Escherichia coli B (T7.B) indicated that the phage DNA was restricted by S. typhimurium. When a mutant T7 which survived the restriction and produced plaques on Salmonella (T7.S) was passed through one cycle of growth in E. coli B, its ability to grow in Salmonella was lost, indicating that host-controlled restriction and modification are operative in this system. Restrictionless S. typhimurium mutants were isolated that permit the growth of not only T7.S but also T7.B and coliphage T3. The physiology of T7 production in the restrictionless host is nearly identical to that in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350708"}
{"pmid": "4350709", "title": "Infectivity and RNA patterns as functions of high- and low-dilution passage of murine sarcoma-leukemia virus: evidence for autointerference within an oncornavirus population.", "content": "Infectivity and RNA patterns as functions of high- and low-dilution passage of murine sarcoma-leukemia virus: evidence for autointerference within an oncornavirus population. Heterogeneity of buoyant density and RNA content of virions of Moloney murine leukemia-sarcoma complex [MSV (MLV)] was the result of passage at low dilution. Heterogeneous stocks revealed two major RNA components in the population, with the smaller component, apparent mol wt 4 x 10(6) to 5 x 10(6), becoming predominant upon serial passage at low dilution. Concomitantly, infectivity titers of both MLV and MSV decreased upon serial passage at low dilution. MSV (MLV) passaged at high dilution retained high titers and a rather homogeneous high-molecular-weight RNA population characteristic of high-buoyant-density virions. Interference of both MLV and MSV replication was demonstrated by employing mixed inocula containing both low- and high-dilution passage stocks of MSV (MLV). In contrast to results with MSV (MLV), MLV freed of MSV by limit dilution did not show heterogeneity of buoyant density or of RNA when propagated at low dilution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350709"}
{"pmid": "4350710", "title": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. V. Isolation of additional hybrids which differ in their simian virus 40-specific biological properties.", "content": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. V. Isolation of additional hybrids which differ in their simian virus 40-specific biological properties. Four new nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid viruses have been isolated. Although these viruses (designated Ad2(+)ND(2), Ad2(+)ND(3), Ad2(+)ND(4), and Ad2(+)ND(5)) were clonal derivatives of the same Ad2-SV40 hybrid population, they differ significantly from each other and from the previously isolated nondefective hybrid, Ad2(+)ND(1), in their biological properties or in the amount of SV40-specific RNA induced during lytic infection.Like Ad2(+)ND(1), Ad2(+)ND(2), and Ad2(+)ND(4) pass serially in both human embryonic kidney (HEK) and primary African green monkey kidney cells. In contrast, Ad2(+)ND(3) and Ad2(+)ND(5) pass serially only in HEK cells. Ad2(+)ND(2) is like Ad2(+)ND(1) in that it induces the SV40 U antigen, but not SV40 T antigen; however, in contrast to the perinuclear SV40 antigen induced by Ad2(+)ND(1), the SV40 antigen induced by Ad2(+)ND(2) is located peripherally in the cytoplasm as well as in the perinuclear region of infected cells. Ad2(+)ND(4) induces both the SV40 T and U antigens. Ad2(+)ND(3) and Ad2(+)ND(5) do not induce serologically detectable SV40 antigens and are distinguished from each other on the basis of the relative quantities of SV40-specific RNA which they induce. The induction of different SV40-specific functions suggests the incorporation of different segments of SV40 DNA within the genomes of the respective hybrid viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350710"}
{"pmid": "4350711", "title": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. VI. Characterization of the DNA from five nondefective hybrid viruses.", "content": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. VI. Characterization of the DNA from five nondefective hybrid viruses. Certain biophysical characteristics of the DNA from each of the five nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid viruses (Ad2(+)ND(1), Ad2(+)ND(2), Ad2(+)ND(3), Ad2(+)ND(4), Ad2(+)ND(5)) have been determined. The guanine plus cytosine content varied from 55 to 57% and was not significantly different from that of nonhybrid Ad2 (56%), and the hybrid DNA molecules had mean molecular lengths which were similar to that of the standard, Ad2. The Ad2 and SV40 components of each hybrid were linked by alkali-resistant, presumably covalent bonds. The percentage of SV40 DNA in each hybrid virus was determined by hybridization with SV40 complementary RNA in a calibrated system. The results indicate that each hybrid virus DNA contains a different percentage of SV40 nucleotide sequences. The estimated size of the SV40 DNA component varies from 48,000 daltons for Ad2(+)ND(3) to 840,000 daltons for Ad2(+)ND(4), the latter being equivalent to between one-fourth and one-third of the SV40 genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350711"}
{"pmid": "4350712", "title": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. VII. Characterization of the simian virus 40 RNA species induced by five nondefective hybrid viruses.", "content": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. VII. Characterization of the simian virus 40 RNA species induced by five nondefective hybrid viruses. Five nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid viruses have been isolated and found to contain segments of SV40 DNA covalently linked to Ad2 DNA. The quantity of SV40 DNA present is a stable characteristic of each hybrid virus, and varies from less than 5% (in Ad2(+)ND(3)) to more than 30% (in Ad2(+)ND(4)) of the SV40 genome. We have characterized the SV40 portions of these hybrids by relating the SV40-specific RNA sequences transcribed in cells infected with each hybrid virus to those transcribed in cells infected with each of the other hybrid viruses and with SV40 itself. RNA-DNA hybridization-competition experiments indicate that the number of unique SV40 RNA sequences transcribed in infected cells is proportional to the size of the SV40 DNA segment contained within each hybrid and, in the case of the three hybrids which induce detectable SV40-specific antigens, to the number of SV40 antigens induced. Furthermore, the SV40-specific RNA sequences transcribed from any one of the hybrids are completely represented in the RNA transcribed from all other hybrids with longer SV40 segments. Thus, the SV40 DNA regions in the five hybrid viruses appear to contain some nucleotide sequences in common. The SV40-specific RNA transcribed from Ad2(+)ND(4), the hybrid containing the largest SV40 segment, is qualitatively similar to the SV40-specific RNA transcribed early (i.e., prior to viral DNA replication) in SV40 lytic infection. Thus, it appears that no significant amount of late SV40 DNA is transcribed during infection by any of the five nondefective Ad2-SV40 hybrid viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350712"}
{"pmid": "4350713", "title": "Preferred site for initiation of RNA transcription by Escherichia coli RNA polymerase within the simian virus 40 DNA segment of the nondefective adenovirus-simian virus 40 hybrid viruses Ad2 + ND 1  and Ad2 + ND 3 .", "content": "Preferred site for initiation of RNA transcription by Escherichia coli RNA polymerase within the simian virus 40 DNA segment of the nondefective adenovirus-simian virus 40 hybrid viruses Ad2 + ND 1  and Ad2 + ND 3 . The DNA of simian virus 40 (SV40) was transcribed into RNA by Escherichia coli RNA polymerase at 18 to 24 C after synchronization of the initiation of RNA synthesis. After a brief synthetic period the RNA product contained relatively large amounts of sequences derived from a limited segment of SV40 DNA. The source for this pulse-labeled RNA was found to be a portion of the segment of SV40 DNA included within the nondefective adenovirus (Ad)-SV40 hybrid viruses, Ad2(+)ND(1) and Ad2(+)ND(3). After synthesis with [gamma-(32)P] ATP, Ad2(+)ND(1) and Ad2(+)ND(3) DNA transcripts contained an initial sequence missing from Ad2 transcripts. This sequence was identified as an initiation sequence for polymerase transcription of the SV40 DNA. Thus, there is a preferred site for initiation of in vitro transcription on the segment of SV40 DNA common to the nondefective Ad2(+)ND(1) and Ad2(+)ND(3) hybrid viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350713"}
{"pmid": "4350714", "title": "Temperature-sensitive simian virus 40-transformed cells: phenomena accompanying transition from the transformed to the \"normal\" state.", "content": "Temperature-sensitive simian virus 40-transformed cells: phenomena accompanying transition from the transformed to the \"normal\" state. Temperature-sensitive simian virus (SV 40)-transformed 3T3 cells (tsSV3T3), which express the transformed phenotype when growing at 32 C but not at 39 C, were used to study changes in growth behavior during shift-up or shift-down experiments. In cultures of tsSV3T3 cells which had reached or were beyond monolayer density at 32 C, DNA synthesis reached very low levels within 24 to 48 h after shift-up. When cells which had been allowed to grow to high densities at 32 C were shifted to 39 C, not only cell growth stopped, but within two to three days the cultures shed a large number of cells into the medium. These cells were nonviable, and shedding stopped only when the number of cells attached had been reduced to that characteristic of the saturation density at 39 C. The remaining attached cells were viable and after the shift to 32 C were again able to grow from the monolayer to high cell densities. This behavior has been compared with that of normal 3T3 and wild-type SV3T3 cells under different conditions. We have also isolated new tsSV3T3 lines, using cells which had been infected with non-mutagenized wild-type SV40. This further demonstrates that the temperature sensitivity of these lines is due to a cellular rather than a viral mutation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350714"}
{"pmid": "4350715", "title": "Structural rearrangement and subunit composition of RNA from released Soehner-Dmochowski murine sarcoma virions.", "content": "Structural rearrangement and subunit composition of RNA from released Soehner-Dmochowski murine sarcoma virions. Two types of genomic, high-molecular-weight RNA species were found in Soehner-Dmochowski murine sarcoma virions released from virus-induced rat tumor cells grown in tissue culture. The type of RNA species observed depended on the length of exposure of the tumor cells to radioactive precursor. Early RNA of virions labeled up to 4 h with radioactive uridine had a sedimentation coefficient of 50S, and late RNA of virions labeled for 24 h had a sedimentation coefficient of 58S. Thermal transitions of early and late RNA indicated a difference in the configuration or structure of these two types of RNA. The late RNA may represent either a different configurational state of the early RNA or an aggregate molecule of two early RNA components joined together. Heat dissociation revealed that the major subunit of both RNA types was a 28S species, which was not susceptible to degradation by the addition of micrococcal nuclease to virions. A transitional, intermediate RNA species with a sedimentation coefficient of 37 to 40S was detected when early RNA was dissociated by dimethyl sulfoxide or heat at temperatures suboptimal for complete conversion. No free RNA subunit components were detected in virions harvested at intervals as short as 30 s or 5 min. A model for the assembly of genomic RNA from 28S RNA subunits is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350715"}
{"pmid": "4350716", "title": "Inhibition in the joining of DNA intermediates to growing simian virus 40 chains.", "content": "Inhibition in the joining of DNA intermediates to growing simian virus 40 chains. Viral DNA synthesis was inhibited for 1 h by the addition of 5-fluorodeoxyuridine (FUdR) to simian virus 40 (SV40)-infected cultures at 28 to 30 h postinfection. The subsequent addition of (3)H-thymidine to the inhibited cultures reverses the effect of the inhibitor, and during a 1-min labeling period there is rapid synthesis of SV40 DNA. By alkaline sedimentation analysis, it is observed that in FUdR-treated cultures there is synthesis of 4S SV40 DNA intermediates but there is a block in the joining of these intermediates to growing SV40 chain cultures. In addition to 4S fragments that are associated with replicating SV40 molecules, there is accumulation of SV40 DNA in the 6 to 8S region which is observed in neutral sucrose gradients. In an inhibited culture that is pulsed for 1 min with (3)H-thymidine and then chased for 10 min, accumulation of a Component II (Comp. II)-like material is observed. This Comp. II has the same neutral sedimentation characteristics and yields the same R(I) restriction endonuclease product as does authentic Comp. II. However, in alkali it is seen that it is composed of fragmented SV40 DNA. The basis for the failure of 4S fragments to join to growing SV40 chains is discussed. A model in which there is a requirement for two DNA polymerases and a ligase to permit SV40 DNA chain growth is proposed which is consistent with the data presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350716"}
{"pmid": "4350717", "title": "Avian oncornavirus group-specific antigen: detection and quantification by radioimmunoassay.", "content": "Avian oncornavirus group-specific antigen: detection and quantification by radioimmunoassay. A double-antibody competitive-inhibition radioimmunoassay for avian group-specific antigen is described. A viral protein preparation, consisting primarily of gs-1, was labeled with radioiodine. Hamster and rabbit antisera were reacted with the labeled antigen, and the resultant antibody-antigen complexes were precipitated with the appropriate antiglobulin. Standard curves based on the inhibition of binding of labeled antigen to antibody after preincubation with unlabeled antigen were prepared. These showed the lower limit of sensitivity to be 2 to 10 ng of unlabeled protein when labeled antigen of 2,000 to 5,000 counts per min per ng of specific activity was used in the assay. Extracts of avian oncornavirus-infected cells, likewise, were able to inhibit binding of labeled antigen. This technique will be very useful for the quantification of small amounts of oncornavirus group-specific protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350717"}
{"pmid": "4350718", "title": "Relationship of reticuloendotheliosis virus to the avian tumor viruses: nucleic acid and polypeptide composition.", "content": "Relationship of reticuloendotheliosis virus to the avian tumor viruses: nucleic acid and polypeptide composition. The RNA content and polypeptide composition of reticuloendotheliosis virus (REV) was compared to that of C-type RNA tumor viruses. Two RNA species with approximate sedimentation values of 64S and 4S were observed after sucrose gradient centrifugation of RNA extracted from purified REV. The high-molecular-weight RNA species of REV sedimented slightly faster than that of the Bryan strain of Rous sarcoma virus (RSV). Although these characteristics were consistent with those of other C-type RNA tumor viruses, significant differences were observed when the polypeptide composition of REV was compared with that of RSV possessing envelope determinants of Rous-associated virus RAV-2 and RAV-3. Five polypeptides of which two were glycosylated were resolved by polyacrylamide gel electrophoresis. The major nonglycosylated polypeptide of REV did not comigrate with that of RSV (RAV-2)-RSV(RAV-3). The majority of the group-specific antigen reactivity resides in this major nonglycosylated polypeptide of avian tumor viruses and comigrates when proteins of several avian tumor viruses are subjected to coelectrophoresis. This difference in the migration of the major polypeptide of REV and RSV(RAV-2)-RSV(RAV-3) may explain the absence of avian tumor virus group-specific antigen in REV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350718"}
{"pmid": "4350719", "title": "Quantitative determination and location of newly synthesized virus-specific ribonucleic acid in chicken cells infected with Rous sarcoma virus.", "content": "Quantitative determination and location of newly synthesized virus-specific ribonucleic acid in chicken cells infected with Rous sarcoma virus. A sensitive and quantitative nucleic acid hybridization assay for the detection of radioactively labeled avian tumor virus-specific RNA in infected chicken cells has been developed. In our experiments we made use of the fact that DNA synthesized by virions of avian myeloblastosis virus in the presence of actinomycin D (AMV DNA) is complementary to at least 35% of the sequences of 70S RNA from the Schmidt-Ruppin strain (SRV) of Rous sarcoma virus. Annealing of radioactive RNA (either SRV RNA or RNA extensively purified from SRV-infected chicken cells) with AMV DNA followed by ribonuclease digestion and Sephadex chromatography yielded products which were characterized as avian tumor virus-specific RNA-DNA hybrids by hybridization competition with unlabeled 70S AMV RNA, equilibrium density-gradient centrifugation in Cs(2)SO(4) gradients, and by analysis of their ribonucleotide composition. The amount of viral RNA synthesized during pulse labeling with (3)H-uridine could be quantitated by the addition of an internal standard consisting of (32)P-labeled SRV RNA prior to purification and hybridization. This quantitative assay was used to determine that, in SRV-infected chicken cells labeled for increasing lengths of time with (3)H-uridine, labeled viral RNA appeared first in a nuclear fraction, then in a cytoplasmic fraction, and still later in mature virions. This observation is consistent with the hypothesis that RNA tumor virus RNA is synthesized in the nucleus of infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350719"}
{"pmid": "4350723", "title": "Stimulation of the collagen biosynthetic pathway by factors isolated from experimentally-injured liver.", "content": "Stimulation of the collagen biosynthetic pathway by factors isolated from experimentally-injured liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350723"}
{"pmid": "4350724", "title": "Action of intracerebroventricular dibutyryl cyclic AMP on amobarbital anaesthesia in rats.", "content": "Action of intracerebroventricular dibutyryl cyclic AMP on amobarbital anaesthesia in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350724"}
{"pmid": "4350725", "title": "Amniotic fluid phospholipids in early gestation.", "content": "Amniotic fluid phospholipids in early gestation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350725"}
{"pmid": "4350727", "title": "Tectal activity and eye movements during paradoxical sleep in cats.", "content": "Tectal activity and eye movements during paradoxical sleep in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350727"}
{"pmid": "4350726", "title": "Pulmonary surfactant. Is the fetal adrenal necessary?", "content": "Pulmonary surfactant. Is the fetal adrenal necessary?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350726"}
{"pmid": "4350728", "title": "The effects of conditioned behaviour and environmental factors on plasma corticosteroid levels in pigs.", "content": "The effects of conditioned behaviour and environmental factors on plasma corticosteroid levels in pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350728"}
{"pmid": "4350729", "title": "Electrographic correlates of sleep behavior in a primitive mammal, the armadillo Dasypus novemcinctus.", "content": "Electrographic correlates of sleep behavior in a primitive mammal, the armadillo Dasypus novemcinctus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350729"}
{"pmid": "4350730", "title": "Rewarding and aversive brain stimulation opposite effects on medial thalamic units.", "content": "Rewarding and aversive brain stimulation opposite effects on medial thalamic units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350730"}
{"pmid": "4350731", "title": "The role of the dorsal nerves of the penis in the sexual behaviour of the male rhesus monkey.", "content": "The role of the dorsal nerves of the penis in the sexual behaviour of the male rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350731"}
{"pmid": "4350732", "title": "Path neuron system of medial forebrain bundle as a possible substrate for hypothalamic self-stimulation.", "content": "Path neuron system of medial forebrain bundle as a possible substrate for hypothalamic self-stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350732"}
{"pmid": "4350733", "title": "Drinking to intracerebral angiotensin II and carbachol: dose-response relationships and ionic involvement.", "content": "Drinking to intracerebral angiotensin II and carbachol: dose-response relationships and ionic involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350733"}
{"pmid": "4350734", "title": "Cellular responses to cyclic AMP.", "content": "Cellular responses to cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350734"}
{"pmid": "4350735", "title": "Enzymatic properties of a repressible acid phosphatase in Neurospora crassa.", "content": "Enzymatic properties of a repressible acid phosphatase in Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350735"}
{"pmid": "4350739", "title": "Neoplasms of the sella turcica region in Ibadan, Nigeria.", "content": "Neoplasms of the sella turcica region in Ibadan, Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350739"}
{"pmid": "4350742", "title": "Homogenous immunochemical drug assays.", "content": "Homogenous immunochemical drug assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350742"}
{"pmid": "4350743", "title": "Immunological assays for drugs in biological samples.", "content": "Immunological assays for drugs in biological samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350743"}
{"pmid": "4350744", "title": "Comparative evaluation of methods for laboratory diagnosis of herpetic eye disease.", "content": "Comparative evaluation of methods for laboratory diagnosis of herpetic eye disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350744"}
{"pmid": "4350747", "title": "Quillaiate of choline iodide: a new monoquaternary neuromuscular blocking agent.", "content": "Quillaiate of choline iodide: a new monoquaternary neuromuscular blocking agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350747"}
{"pmid": "4350748", "title": "Subcellular distribution of adenyl cyclase and phosphodiesterase in Acanthamoeba palestinensis.", "content": "Subcellular distribution of adenyl cyclase and phosphodiesterase in Acanthamoeba palestinensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350748"}
{"pmid": "4350749", "title": "Studies with phosphodiesterase. 3. Two forms of the enzyme from human blood platelets.", "content": "Studies with phosphodiesterase. 3. Two forms of the enzyme from human blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350749"}
{"pmid": "4350745", "title": "Incisional and peritoneal infection after emergency celiotomy.", "content": "Incisional and peritoneal infection after emergency celiotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350745"}
{"pmid": "4350750", "title": "Substrate specificity of hog plasma angiotensin-converting enzyme.", "content": "Substrate specificity of hog plasma angiotensin-converting enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350750"}
{"pmid": "4350757", "title": "Histamine sensitizing activity of lentinan, an antitumour polysaccharide.", "content": "Histamine sensitizing activity of lentinan, an antitumour polysaccharide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350757"}
{"pmid": "4350756", "title": "The renin-angiotensin system in urinephrectomized adrenalectomized rats.", "content": "The renin-angiotensin system in urinephrectomized adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350756"}
{"pmid": "4350758", "title": "A quantitative investigation of the response to injury of the central nervous system of rats treated with ACTH and triiodothyronine.", "content": "A quantitative investigation of the response to injury of the central nervous system of rats treated with ACTH and triiodothyronine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350758"}
{"pmid": "4350760", "title": "Radioimmunoassay of angiotensin II in rat plasma.", "content": "Radioimmunoassay of angiotensin II in rat plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350760"}
{"pmid": "4350759", "title": "The primary tissue culture of rat adult decapsulated adrenal glands: radioautographic studies on the metabolic effects of   1-24 -ACTH.", "content": "The primary tissue culture of rat adult decapsulated adrenal glands: radioautographic studies on the metabolic effects of   1-24 -ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350759"}
{"pmid": "4350763", "title": "Strength modification of polycarboxylate cement with fillers.", "content": "Strength modification of polycarboxylate cement with fillers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350763"}
{"pmid": "4350764", "title": "Further studies on the chromatographic behaviour of dinucleoside monophosphates.", "content": "Further studies on the chromatographic behaviour of dinucleoside monophosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350764"}
{"pmid": "4350765", "title": "Preparative argentation column chromatography for separation of sterols from orange vesicles.", "content": "Preparative argentation column chromatography for separation of sterols from orange vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350765"}
{"pmid": "4350766", "title": "Application of direct spectrophotometry to the analysis of chromatograms. 3. A new micro thin-layer chromatoplate and its application to the analysis of tocopherols.", "content": "Application of direct spectrophotometry to the analysis of chromatograms. 3. A new micro thin-layer chromatoplate and its application to the analysis of tocopherols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350766"}
{"pmid": "4350767", "title": "Detection of naturally fluorescent pesticides on silica gel layers.", "content": "Detection of naturally fluorescent pesticides on silica gel layers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350767"}
{"pmid": "4350769", "title": "The formation of synapses in reinnervated and cross-reinnervated adult avian muscle.", "content": "The formation of synapses in reinnervated and cross-reinnervated adult avian muscle. 1. A study has been made of the formation of synapses in spontaneously reinnervated and cross-reinnervated anterior latissimus dorsi (ALD) and posterior latissimus dorsi (PLD) muscles of adult fowls.2. Denervated ALD and PLD muscle fibres have a uniform and high sensitivity to iontophoretically applied acetylcholine (ACh). During early reinnervation the sensitivity distribution to ACh of the ALD muscle fibres begins to return to normal before synaptic potentials can be evoked. The normal ACh sensitivity distribution of PLD muscle fibres is also restored after reinnervation. After cross-reinnervation of the ALD and PLD muscles the ACh sensitivity distribution of many of the muscle fibres is again restored to normal.3. Reinnervating and cross-reinnervating ALD nerve terminals showed a greater than normal degree of facilitation of transmitter release when a test impulse was applied at various intervals after a conditioning impulse. Cross-reinnervating PLD nerve terminals showed facilitation of transmitter release rather than the normal depression in a conditioning-test impulse sequence.4. The distribution of nerve terminals over the surface of spontaneously reinnervated and cross-reinnervated ALD and PLD muscle fibres has been determined from an examination of the sensitivity distribution to applied ACh, the graded versus all-or-none nature of the evoked potential and the distribution of cholinesterase stained synapses.5. The results suggest that the innervation pattern of individual ALD and PLD muscle fibres is restored both after spontaneous reinnervation and cross-reinnervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350769"}
{"pmid": "4350771", "title": "Effects of muscle stretch on transmitter release at end-plates of rat diaphragm and frog sartorius muscle.", "content": "Effects of muscle stretch on transmitter release at end-plates of rat diaphragm and frog sartorius muscle. 1. Miniature end-plate potentials (m.e.p.p.s) and end-plate potentials were recorded intracellularly at neuromuscular junctions of the frog sartorius muscle and the rat diaphragm before, during and after muscle stretch.2. Stretch increased the frequency of the m.e.p.p.s and the mean quantum content (m) at end-plates of the sartorius muscle.3. Stretch enhanced m.e.p.p. frequency of the sartorius muscle in normal Ringer solution as well as in solutions high in magnesium and low in calcium content. In addition, an increase in frequency occurred in the presence of tetrodotoxin and in the absence of neostigmine methylsulphate.4. The magnitude of the increase in m.e.p.p. frequency in the sartorius muscle was negatively correlated with the control frequency.5. In contrast to the above findings at sartorius end-plates, muscle stretch did not affect the frequency of m.e.p.p.s or the m values at end-plates of the rat diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350771"}
{"pmid": "4350770", "title": "The orderly recruitment of human motor units during voluntary isometric contractions.", "content": "The orderly recruitment of human motor units during voluntary isometric contractions. 1. The contractile properties of human motor units from the first dorsal interosseus muscle of the hand were studied during voluntary isometric contractions using recently developed techniques.2. The twitch tensions produced by motor units varied widely from about 0.1-10 g. The twitch tension of a motor unit varied nearly linearly as a function of the level of voluntary force at which it was recruited over the entire range of forces studied (0-2 kg).3. The number of additional motor units recruited during a given increment in force declined sharply at high levels of voluntary force. This suggests that even though the high threshold units generate more tension, the contribution of recruitment to increases in voluntary force declines at higher force levels.4. Contraction times for these motor units varied from 30 to 100 msec. Over 80% had contraction times less than 70 msec, and might be classed as fast twitch motor units. The larger motor units, which were recruited at higher threshold forces, tended to have shorter contraction times than the smaller units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350770"}
{"pmid": "4350773", "title": "Maternal infections and the developing foetus.", "content": "Maternal infections and the developing foetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350773"}
{"pmid": "4350776", "title": "Patterning mechanisms, patterned reflexes, and attack behavior in cats.", "content": "Patterning mechanisms, patterned reflexes, and attack behavior in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350776"}
{"pmid": "4350775", "title": "Maternal cytomegalovirus excretion and perinatal infection.", "content": "Maternal cytomegalovirus excretion and perinatal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350775"}
{"pmid": "4350777", "title": "Influence of levodopa on serum levels of anterior pituitary hormones in man.", "content": "Influence of levodopa on serum levels of anterior pituitary hormones in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350777"}
{"pmid": "4350778", "title": "Neural pathways mediating adrenocortical responses to photic and acoustic stimuli.", "content": "Neural pathways mediating adrenocortical responses to photic and acoustic stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350778"}
{"pmid": "4350779", "title": "Management of nursing care on a psychiatric service.", "content": "Management of nursing care on a psychiatric service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350779"}
{"pmid": "4350780", "title": "Patterns of development of adenyl cyclase activity and norepinephrine responsiveness in the rat.", "content": "Patterns of development of adenyl cyclase activity and norepinephrine responsiveness in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350780"}
{"pmid": "4350781", "title": "Sleep patterns in hyperphenylalaninemia: a lesson on serotonin to be learned from phenylketonuria.", "content": "Sleep patterns in hyperphenylalaninemia: a lesson on serotonin to be learned from phenylketonuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350781"}
{"pmid": "4350783", "title": "Inhibition of glucose oxidation and fatty acid synthesis in liver slices from fed, fasted and fasted-refed rats by glucagon, epinephrine and cyclic adenosine-3',5'-monophosphate.", "content": "Inhibition of glucose oxidation and fatty acid synthesis in liver slices from fed, fasted and fasted-refed rats by glucagon, epinephrine and cyclic adenosine-3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350783"}
{"pmid": "4350782", "title": "Characterization of guinea pig C-type virus.", "content": "Characterization of guinea pig C-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350782"}
{"pmid": "4350784", "title": "Effect of the synthetic peptide, Sq 20,881, on distribution of blood flow in the rat.", "content": "Effect of the synthetic peptide, Sq 20,881, on distribution of blood flow in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350784"}
{"pmid": "4350786", "title": "HL-A antigens of human tumor-derived cell lines and viral transformed fibroblasts in culture.", "content": "HL-A antigens of human tumor-derived cell lines and viral transformed fibroblasts in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350786"}
{"pmid": "4350785", "title": "Estrogen-topographical localization of estrogen-concentrating cells in the rat spinal cord following  3 H-estradiol administration.", "content": "Estrogen-topographical localization of estrogen-concentrating cells in the rat spinal cord following  3 H-estradiol administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350785"}
{"pmid": "4350787", "title": "Adrenal and plasma corticosterone and pituitary and plasma ACTH in alloxan diabetic rats.", "content": "Adrenal and plasma corticosterone and pituitary and plasma ACTH in alloxan diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350787"}
{"pmid": "4350788", "title": "Immunosuppression and increased susceptibility to Japaneses B encephalitis virus in Trichinella spiralis-infected mice.", "content": "Immunosuppression and increased susceptibility to Japaneses B encephalitis virus in Trichinella spiralis-infected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350788"}
{"pmid": "4350789", "title": "Effects of prostaglandins PGE 2  and PGF 2   on the adenyl cyclase activity of various segments of the immature rabbit oviduct and uterus.", "content": "Effects of prostaglandins PGE 2  and PGF 2   on the adenyl cyclase activity of various segments of the immature rabbit oviduct and uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350789"}
{"pmid": "4350790", "title": "Endogenous triglyceride and glycogen in perfused rat hearts.", "content": "Endogenous triglyceride and glycogen in perfused rat hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350790"}
{"pmid": "4350791", "title": "B-scan ultrasound in the evaluation of pediatric abdominal masses.", "content": "B-scan ultrasound in the evaluation of pediatric abdominal masses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350791"}
{"pmid": "4350793", "title": "Mammary duct injection.", "content": "Mammary duct injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350793"}
{"pmid": "4350792", "title": "The incidence of osseous involvement in lung cancer, with special reference to the development of osteoblastic changes.", "content": "The incidence of osseous involvement in lung cancer, with special reference to the development of osteoblastic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350792"}
{"pmid": "4350796", "title": "Evidence on the constitutive nature of a p-nitrophenylphosphatase of Streptococcus mutans.", "content": "Evidence on the constitutive nature of a p-nitrophenylphosphatase of Streptococcus mutans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350796"}
{"pmid": "4350797", "title": "Significance of a p-nitrophenylphosphatase for Streptococcus mutans.", "content": "Significance of a p-nitrophenylphosphatase for Streptococcus mutans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350797"}
{"pmid": "4350798", "title": "Epidemiologic characteristics of presumed ocular histoplasmosis.", "content": "Epidemiologic characteristics of presumed ocular histoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350798"}
{"pmid": "4350799", "title": "Changes in lipid values and lipoprotein patterns of serum samples contaminated with bacteria.", "content": "Changes in lipid values and lipoprotein patterns of serum samples contaminated with bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350799"}
{"pmid": "4350800", "title": "Automated stopped-flow kinetic analysis of serum enzymes.", "content": "Automated stopped-flow kinetic analysis of serum enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350800"}
{"pmid": "4350801", "title": "pH dependence of the renin reaction: a modification of commercial renin activity radioimmunoassay kits.", "content": "pH dependence of the renin reaction: a modification of commercial renin activity radioimmunoassay kits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350801"}
{"pmid": "4350803", "title": "Corneal degeneration.", "content": "Corneal degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350803"}
{"pmid": "4350802", "title": "Antiviral activity of isoprinosine in vitro and in vivo.", "content": "Antiviral activity of isoprinosine in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350802"}
{"pmid": "4350805", "title": "Microsomal electron transport: tetrazolium reduction by rat liver microsomal NADPH-cytochrome c reductase.", "content": "Microsomal electron transport: tetrazolium reduction by rat liver microsomal NADPH-cytochrome c reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350805"}
{"pmid": "4350804", "title": "Effect of the pH of the incubation medium on glycolysis and respiration in Saccharomyces cerevisiae.", "content": "Effect of the pH of the incubation medium on glycolysis and respiration in Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350804"}
{"pmid": "4350806", "title": "Bovine hepatic fructose 1,6-diphosphatase: modification of the catalytic and allosteric properties by sulfhydryl reagents.", "content": "Bovine hepatic fructose 1,6-diphosphatase: modification of the catalytic and allosteric properties by sulfhydryl reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350806"}
{"pmid": "4350807", "title": "Protein synthesis directed by encephalomyocarditis virus mRNA. 3. Discrete polypeptides translated from a monocistronic messenger in vitro.", "content": "Protein synthesis directed by encephalomyocarditis virus mRNA. 3. Discrete polypeptides translated from a monocistronic messenger in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350807"}
{"pmid": "4350808", "title": "Interaction of viral RNA with Escherichia coli. 3. Synthesis of poliovirus-specific RNA directed by isolated poliovirus RNA.", "content": "Interaction of viral RNA with Escherichia coli. 3. Synthesis of poliovirus-specific RNA directed by isolated poliovirus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350808"}
{"pmid": "4350809", "title": "Purification and properties of cyclic phosphodiesterase: 3'-nucleotidase, a periplasmic enzyme of Haemophilus influenzae.", "content": "Purification and properties of cyclic phosphodiesterase: 3'-nucleotidase, a periplasmic enzyme of Haemophilus influenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350809"}
{"pmid": "4350810", "title": "On the source of GABA-containing terminals in the substantia nigra. Electron microscopic autoradiographic and biochemical studies.", "content": "On the source of GABA-containing terminals in the substantia nigra. Electron microscopic autoradiographic and biochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350810"}
{"pmid": "4350811", "title": "Neuronal activity in the association cortex of the cat during sleep, wakefulness and anesthesia.", "content": "Neuronal activity in the association cortex of the cat during sleep, wakefulness and anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350811"}
{"pmid": "4350812", "title": "Compensatory changes in REM sleep time of cats during ad libitum sleep and following brief REM sleep deprivation.", "content": "Compensatory changes in REM sleep time of cats during ad libitum sleep and following brief REM sleep deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350812"}
{"pmid": "4350813", "title": "Miniature end-plate potentials: evidence that the intervals are not fit by a Poisson distribution.", "content": "Miniature end-plate potentials: evidence that the intervals are not fit by a Poisson distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350813"}
{"pmid": "4350815", "title": "Action of a GABA-derivative on postsynaptic potentials and membrane properties of cats' spinal motoneurones.", "content": "Action of a GABA-derivative on postsynaptic potentials and membrane properties of cats' spinal motoneurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350815"}
{"pmid": "4350814", "title": "Some effects of vinblastine and colchicine on neuromuscular transmission.", "content": "Some effects of vinblastine and colchicine on neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350814"}
{"pmid": "4350816", "title": "Scorpion venom-induced discharge of catecholamines accompanied by hypertension.", "content": "Scorpion venom-induced discharge of catecholamines accompanied by hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350816"}
{"pmid": "4350823", "title": "Ribosome-covered vesicles associated with synthesis and secretion of invertase in yeast.", "content": "Ribosome-covered vesicles associated with synthesis and secretion of invertase in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350823"}
{"pmid": "4350824", "title": "The long-acting thyroid stimulator.", "content": "The long-acting thyroid stimulator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350824"}
{"pmid": "4350826", "title": "Effects of ovarian hormones at the subcellular level.", "content": "Effects of ovarian hormones at the subcellular level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350826"}
{"pmid": "4350825", "title": "Endocrinological implications of prostaglandins.", "content": "Endocrinological implications of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350825"}
{"pmid": "4350827", "title": "Steroid hormones and the differentiation of the central nervous system.", "content": "Steroid hormones and the differentiation of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350827"}
{"pmid": "4350828", "title": "Polygraphic profile of oral tardive dyskinesia and of rabbit syndrome: for quantitative and qualitative evaluation.", "content": "Polygraphic profile of oral tardive dyskinesia and of rabbit syndrome: for quantitative and qualitative evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350828"}
{"pmid": "4350830", "title": "Gout and pseudogout.", "content": "Gout and pseudogout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350830"}
{"pmid": "4350832", "title": "Ultrastructural and lipid biochemical comparisons of human eruptive, tuberous and planar xanthomas.", "content": "Ultrastructural and lipid biochemical comparisons of human eruptive, tuberous and planar xanthomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350832"}
{"pmid": "4350833", "title": "Virus-induced changes in the endogenous pathway of thymidine in animal cells.", "content": "Virus-induced changes in the endogenous pathway of thymidine in animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350833"}
{"pmid": "4350834", "title": "An ultrastructural analysis of the photoreceptors of the squid and their synaptic connections. II. Intraretinal synapses and plexus.", "content": "An ultrastructural analysis of the photoreceptors of the squid and their synaptic connections. II. Intraretinal synapses and plexus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350834"}
{"pmid": "4350836", "title": "Indirect haemagglutination reaction with varicella-zoster virus antigen.", "content": "Indirect haemagglutination reaction with varicella-zoster virus antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350836"}
{"pmid": "4350835", "title": "Identification of a major basic protein in guinea pig eosinophil granules.", "content": "Identification of a major basic protein in guinea pig eosinophil granules. Elucidation of the functions of the eosinophil might be accomplished by analysis of the granule constituents. We have purified eosinophils (93% or greater) from the peritoneal cavity of the guinea pig and have investigated a variety of methods to disrupt cells and liberate intact granules. Lysis in 0.34 M sucrose gave the best yield of granules and these had the characteristic morphology of eosinophil granules when examined by electron microscopy. Granules were solubilized by a variety of treatments and the solutions analyzed by polyacrylamide electrophoresis at pH 3 in 6 M urea. Comparison of the electrophoretic patterns of solubilized eosinophil and neutrophil granules revealed a difference: a major portion (53+/-3%; x +/-1 SE) of the protein from the eosinophil granule migrated as a single component. This major band protein has a molecular weight between 6,000 and 12,000 daltons and a pI of 10 or greater. Analysis of eosinophil granule constituents on Sephadex G-50 revealed two main peaks; peak 1 possessed peroxidase activity and peak 2 contained the major band protein. These studies indicate that eosinophil granules contain a cationic protein of low molecular weight which lacks peroxidase activity and which accounts for greater than 50% of granule protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350835"}
{"pmid": "4350837", "title": "An analysis of cylindroma of the head and neck.", "content": "An analysis of cylindroma of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350837"}
{"pmid": "4350838", "title": "Plasma renin activity during levodopa therapy. Significance of long- and short-term treatment.", "content": "Plasma renin activity during levodopa therapy. Significance of long- and short-term treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350838"}
{"pmid": "4350839", "title": "Stand up and be diagnosed.", "content": "Stand up and be diagnosed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350839"}
{"pmid": "4350844", "title": "Reversible inactivation of liver microsomal pyrophosphatase.", "content": "Reversible inactivation of liver microsomal pyrophosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350844"}
{"pmid": "4350845", "title": "Effect of clofibrate on arginine-induced insulin and glucagon secretion.", "content": "Effect of clofibrate on arginine-induced insulin and glucagon secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350845"}
{"pmid": "4350846", "title": "Effects of a purified growth hormone releasing factor on growth hormone secretion and pituitary cyclic nucleotide content.", "content": "Effects of a purified growth hormone releasing factor on growth hormone secretion and pituitary cyclic nucleotide content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350846"}
{"pmid": "4350847", "title": "Precursors of plasma triglyceride fatty acids in obesity.", "content": "Precursors of plasma triglyceride fatty acids in obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350847"}
{"pmid": "4350849", "title": "Triglyceride removal efficiency and lipoprotein lipases: effects of Oxandrolone.", "content": "Triglyceride removal efficiency and lipoprotein lipases: effects of Oxandrolone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350849"}
{"pmid": "4350848", "title": "Increase of microsomal glucose-6-phosphatase activity after chronic ethanol administration.", "content": "Increase of microsomal glucose-6-phosphatase activity after chronic ethanol administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350848"}
{"pmid": "4350851", "title": "Sensory transduction. II. Visual receptors. Quantum efficiency of isomerization.", "content": "Sensory transduction. II. Visual receptors. Quantum efficiency of isomerization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350851"}
{"pmid": "4350850", "title": "Brain, speech and consciousness.", "content": "Brain, speech and consciousness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350850"}
{"pmid": "4350856", "title": "Immunization of chickens for the control of infectious bursal disease.", "content": "Immunization of chickens for the control of infectious bursal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350856"}
{"pmid": "4350857", "title": "The inheritance of resistance to subgroup C leukosis-sarcoma viruses in New Hampshire chickens.", "content": "The inheritance of resistance to subgroup C leukosis-sarcoma viruses in New Hampshire chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350857"}
{"pmid": "4350858", "title": "Horizontal transmission of turkey herpesvirus to chickens. 2. Some factors affecting transmission.", "content": "Horizontal transmission of turkey herpesvirus to chickens. 2. Some factors affecting transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350858"}
{"pmid": "4350859", "title": "Modification of high temperature and ACTH induced immunodepression by metyrapone.", "content": "Modification of high temperature and ACTH induced immunodepression by metyrapone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350859"}
{"pmid": "4350860", "title": "Conversion of glutamic acid to proline in the chick.", "content": "Conversion of glutamic acid to proline in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350860"}
{"pmid": "4350861", "title": "Regression of Rous sarcomas in two lines of chickens.", "content": "Regression of Rous sarcomas in two lines of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350861"}
{"pmid": "4350867", "title": "Characteristics of physicians interested in psychiatric education.", "content": "Characteristics of physicians interested in psychiatric education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350867"}
{"pmid": "4350873", "title": "Ovarian tumors in pregnancy. A private hospital ten year survey.", "content": "Ovarian tumors in pregnancy. A private hospital ten year survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350873"}
{"pmid": "4350874", "title": "Carbohydrate metabolism during differentiation (sclerotization) of the myxomycete Physarum flavicomum.", "content": "Carbohydrate metabolism during differentiation (sclerotization) of the myxomycete Physarum flavicomum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350874"}
{"pmid": "4350875", "title": "Cortico-fugal facilitation of thalamic transmission.", "content": "Cortico-fugal facilitation of thalamic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350875"}
{"pmid": "4350876", "title": "Discussion: functional studies of thalamic internuclear interactions.", "content": "Discussion: functional studies of thalamic internuclear interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350876"}
{"pmid": "4350877", "title": "The second international standard for polymyxin B.", "content": "The second international standard for polymyxin B. Since supplies of the first International Standard for Polymyxin B were exhausted, it was replaced by a second international standard the potency of which was estimated from the results of a collaborative assay carried out by 5 laboratories in 4 countries. The wide variations in the results probably resulted from difficulties experienced in handling the first international standard. The potency finally agreed upon by the collaborating laboratories, on the basis of the overall mean values obtained after rejection of the most discrepant assays, was 8 403 IU/mg. That value was accepted by the WHO Expert Committee on Biological Standardization (1970), which consequently defined the International Unit of polymyxin B as the activity contained in 0.000119 mg of the second international standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350877"}
{"pmid": "4350878", "title": "Intraaortic balloon pumping for ventricular septal defect or mitral regurgitation complicating acute myocardial infarction.", "content": "Intraaortic balloon pumping for ventricular septal defect or mitral regurgitation complicating acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350878"}
{"pmid": "4350879", "title": "Effects of infections on pregnancy risk.", "content": "Effects of infections on pregnancy risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350879"}
{"pmid": "4350880", "title": "Antibody tests in streptococcal pharyngitis. Streptozyme versus conventional methods.", "content": "Antibody tests in streptococcal pharyngitis. Streptozyme versus conventional methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350880"}
{"pmid": "4350881", "title": "Labial fusion: a cause of recurrent urinary tract infections.", "content": "Labial fusion: a cause of recurrent urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350881"}
{"pmid": "4350882", "title": "Differentiation of human cortical neurons: proteins of subcellular particles.", "content": "Differentiation of human cortical neurons: proteins of subcellular particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350882"}
{"pmid": "4350886", "title": "Enhancement of senescence in low passage human embryonic lung cells by an agent extracted from phase 3 cells.", "content": "Enhancement of senescence in low passage human embryonic lung cells by an agent extracted from phase 3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350886"}
{"pmid": "4350885", "title": "Stepwise accumulation of autoregulated enzyme activities during the cell cycle of the eucaryote Chlorella.", "content": "Stepwise accumulation of autoregulated enzyme activities during the cell cycle of the eucaryote Chlorella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350885"}
{"pmid": "4350887", "title": "The effect of photosensitizing dyes on the  3 H-tymidine incorporation of cells growth in vitro.", "content": "The effect of photosensitizing dyes on the  3 H-tymidine incorporation of cells growth in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350887"}
{"pmid": "4350888", "title": "Myogenic cells derived from murine sarcoma virus induced mouse tumours: DNA synthesis and the effects of Simian virus 40 infection.", "content": "Myogenic cells derived from murine sarcoma virus induced mouse tumours: DNA synthesis and the effects of Simian virus 40 infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350888"}
{"pmid": "4350889", "title": "Activation of nuclear chromatin and the release from contact-inhibition of 3T3 cells.", "content": "Activation of nuclear chromatin and the release from contact-inhibition of 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350889"}
{"pmid": "4350890", "title": "Maturation-stimulating effect of brain extract and dibutyryl cyclic AMP on dissociated embryonic brain cells in culture.", "content": "Maturation-stimulating effect of brain extract and dibutyryl cyclic AMP on dissociated embryonic brain cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350890"}
{"pmid": "4350893", "title": "Differential sensitivity of antigen- and mitogen-stimulated human leucocytes to prolonged inhibition of potassium transport.", "content": "Differential sensitivity of antigen- and mitogen-stimulated human leucocytes to prolonged inhibition of potassium transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350893"}
{"pmid": "4350891", "title": "Citric acid-sonication method for the isolation of nucleoli.", "content": "Citric acid-sonication method for the isolation of nucleoli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350891"}
{"pmid": "4350892", "title": "Deoxyribonuclease in sea urchin embryos. Comparison of the activity present in developing embryos, in nuclei, and in mitochondria.", "content": "Deoxyribonuclease in sea urchin embryos. Comparison of the activity present in developing embryos, in nuclei, and in mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350892"}
{"pmid": "4350884", "title": "The kinetics of transmitter release in myasthenia gravis. I. An electrophysiological analysis of the storage of transmitter.", "content": "The kinetics of transmitter release in myasthenia gravis. I. An electrophysiological analysis of the storage of transmitter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350884"}
{"pmid": "4350895", "title": "Phosphatases from rice bran.", "content": "Phosphatases from rice bran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350895"}
{"pmid": "4350896", "title": "Inhibition of hexosephosphate aminotransferase activity in vitro by tolbutamide.", "content": "Inhibition of hexosephosphate aminotransferase activity in vitro by tolbutamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350896"}
{"pmid": "4350894", "title": "Semipermeable membranes for improving the histochemical demonstration of enzyme activities in tissue sections. 3. Lactate dehydrogenase.", "content": "Semipermeable membranes for improving the histochemical demonstration of enzyme activities in tissue sections. 3. Lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350894"}
{"pmid": "4350897", "title": "Studies on L-glycerol-3-phosphate dehydrogenases in Japanese Quail, Coturnix coturnix japonica. II. Comparison of activity of mitochondrial and cytoplasmic L-glycerol-3-phosphate dehydrogenases in testes and liver of developing male Japanese quail.", "content": "Studies on L-glycerol-3-phosphate dehydrogenases in Japanese Quail, Coturnix coturnix japonica. II. Comparison of activity of mitochondrial and cytoplasmic L-glycerol-3-phosphate dehydrogenases in testes and liver of developing male Japanese quail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350897"}
{"pmid": "4350898", "title": "DNA-dependent RNA polymerase from Ehrlich ascites tumor cells. I. Partial purification and characterization of RNA polymerase II.", "content": "DNA-dependent RNA polymerase from Ehrlich ascites tumor cells. I. Partial purification and characterization of RNA polymerase II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350898"}
{"pmid": "4350899", "title": "Biochemical studies on sulfate-reducing bacteria. XII. Some properties of flavodoxin from Desulfovibrio vulgaris.", "content": "Biochemical studies on sulfate-reducing bacteria. XII. Some properties of flavodoxin from Desulfovibrio vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350899"}
{"pmid": "4350900", "title": "The crystal structure of bonito (Katsuo) ferrocytochrome c at 2.3 A resolution.", "content": "The crystal structure of bonito (Katsuo) ferrocytochrome c at 2.3 A resolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350900"}
{"pmid": "4350901", "title": "Synthetic analogues of polynucleotides. IX. Synthesis of 3'-O-carboxymethyl-2'-deoxyribonucleosides and their use in the synthesis of an analogue of 2'-deoxyadenylyl-(3' leads to 5'-)-thymidine 3'-phosphate.", "content": "Synthetic analogues of polynucleotides. IX. Synthesis of 3'-O-carboxymethyl-2'-deoxyribonucleosides and their use in the synthesis of an analogue of 2'-deoxyadenylyl-(3' leads to 5'-)-thymidine 3'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350901"}
{"pmid": "4350902", "title": "The influence of silica gel G on the quantitative analysis of lipid phosphorus.", "content": "The influence of silica gel G on the quantitative analysis of lipid phosphorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350902"}
{"pmid": "4350904", "title": "Fine-structural aspects of macrogametogenesis in Eimeria magna.", "content": "Fine-structural aspects of macrogametogenesis in Eimeria magna.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350904"}
{"pmid": "4350905", "title": "The effects of actinomycin D, gibberellin A7, and cyclic AMP on mating of Chlamydomonas reinhardtii.", "content": "The effects of actinomycin D, gibberellin A7, and cyclic AMP on mating of Chlamydomonas reinhardtii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350905"}
{"pmid": "4350907", "title": "Growth phase and the number of phosphorylation sites in the mitochondrial electron transport chain of Acanthamoeba castellanii.", "content": "Growth phase and the number of phosphorylation sites in the mitochondrial electron transport chain of Acanthamoeba castellanii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350907"}
{"pmid": "4350908", "title": "Current therapy of Wilms' tumor.", "content": "Current therapy of Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350908"}
{"pmid": "4350909", "title": "Juvenile nasopharyngeal angiofibroma.", "content": "Juvenile nasopharyngeal angiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350909"}
{"pmid": "4350911", "title": "Otoneurology.", "content": "Otoneurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350911"}
{"pmid": "4350912", "title": "Peripheral nerve surgery.", "content": "Peripheral nerve surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350912"}
{"pmid": "4350913", "title": "General neurophysiology: bioelectric aspects.", "content": "General neurophysiology: bioelectric aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350913"}
{"pmid": "4350903", "title": "Effects of liothyronine-induced hypermetabolism on dipyrone metabolism in man.", "content": "Effects of liothyronine-induced hypermetabolism on dipyrone metabolism in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350903"}
{"pmid": "4350914", "title": "Regional physiology of the nervous system.", "content": "Regional physiology of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350914"}
{"pmid": "4350915", "title": "Neuropathology.", "content": "Neuropathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350915"}
{"pmid": "4350916", "title": "Clinical neurology.", "content": "Clinical neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350916"}
{"pmid": "4350917", "title": "Effect of REM sleep deprivation on electric shock threshold in rats.", "content": "Effect of REM sleep deprivation on electric shock threshold in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350917"}
{"pmid": "4350920", "title": "Some aspects of nucleoside and nucleotide metabolism in the peripheral leukocytes during kidney allograft rejection.", "content": "Some aspects of nucleoside and nucleotide metabolism in the peripheral leukocytes during kidney allograft rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350920"}
{"pmid": "4350922", "title": "Correlations between some economic, social and infectious factors and the pathology of pregnancy and of the neonate.", "content": "Correlations between some economic, social and infectious factors and the pathology of pregnancy and of the neonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350922"}
{"pmid": "4350923", "title": "Comparative studies on some herpes simplex virus strains with different locations. II. Study of the virulence character.", "content": "Comparative studies on some herpes simplex virus strains with different locations. II. Study of the virulence character.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350923"}
{"pmid": "4350924", "title": "The action of human immunoglobulins in experimental herpes infection in the newborn rat.", "content": "The action of human immunoglobulins in experimental herpes infection in the newborn rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350924"}
{"pmid": "4350926", "title": "Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.", "content": "Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350926"}
{"pmid": "4350927", "title": "Slow viruses: role in persistent disease.", "content": "Slow viruses: role in persistent disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350927"}
{"pmid": "4350928", "title": "Postlesion axonal growth produces permanent functional connections.", "content": "Postlesion axonal growth produces permanent functional connections. Lesions of the entorhinal cortex in neonatal rats cause the commissural projections to the dentate gyrus to spread from their normal location in the inner molecular layer into the outer molecular layer, a region normally occupied by afferents from the entorhinal cortex. These lesions also cause the short-latency response to commissural stimulation to spread into the outer molecular layer, a result suggesting that these abnormally located connections are operative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350928"}
{"pmid": "4350930", "title": "Angiotensin-sodium interaction in blood pressure maintenance of renal hypertensive and normotensive rats.", "content": "Angiotensin-sodium interaction in blood pressure maintenance of renal hypertensive and normotensive rats. A specific inhibitor of angiotensin II was used in rats to investigate whether angiotensin is involved in the maintenance of blood pressure in one-kidney Goldblatt hypertension, in which plasma renin levels are not usually increased. The inhibitor produced marked falls in blood pressure, often down to normal levels in the hypertensive animals only when they were depleted in sodium and not after sodium repletion. Much lesser but still significant falls in blood pressure were also produced in normotensive sodium-depleted rats but not in repleted rats. We conclude that the importance of angiotensin for maintaining blood pressure is largely determined by its relation to available sodium or fluid volume, since the renin component in maintenance of either the hypertensive or the normotensive state could be exposed only by sodium deprivation. Therefore, volume expansion per se or other pressor factors may be involved in maintaining blood pressure of these sodium-replete normotensive or hypertensive animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350930"}
{"pmid": "4350929", "title": "Delta 9 -tetrahydrocannabinol and ethanol: differential effects on sympathetic activity in differing environmental setting.", "content": "Delta 9 -tetrahydrocannabinol and ethanol: differential effects on sympathetic activity in differing environmental setting. Serum dopamine beta-hydroxylase activity, a useful biochemical index of peripheral sympathetic nervous activity, was measured in rats treated with Delta(9)-tetrahydrocannabinol or ethanol or both substances. After 7 days of treatment with either substance, serum dopamine beta-hydroxylase activity decreased significantly. Combined treatment with both agents enhanced the effects of each given alone. In rats subjected to immobilization stress, treatment with Delta(9)- tetrahydrocannabinol appeared to potentiate the stress-induced increase in serum enzyme activity. Treatment with ethanol, with or without Delta(9)-tetrahydrocannabinol, effectively blocked this increase in enzyme activity. These results show that both substances have significant effects on the sympathetic nervous system which are critically influenced by environmental setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350929"}
{"pmid": "4350935", "title": "The effect of iodine prophylaxis on the incidence of endemic cretinism.", "content": "The effect of iodine prophylaxis on the incidence of endemic cretinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350935"}
{"pmid": "4350936", "title": "Effect of iodine correction early in fetal life on intelligence quotient. A preliminary report.", "content": "Effect of iodine correction early in fetal life on intelligence quotient. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350936"}
{"pmid": "4350937", "title": "Prophylaxis of endemic goiter with iodized oil in rural Peru.", "content": "Prophylaxis of endemic goiter with iodized oil in rural Peru.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350937"}
{"pmid": "4350938", "title": "The optimal program for prophylaxis of endemic goiter with iodized oil.", "content": "The optimal program for prophylaxis of endemic goiter with iodized oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350938"}
{"pmid": "4350939", "title": "IQ tests and intelligence in endemic cretinism.", "content": "IQ tests and intelligence in endemic cretinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350939"}
{"pmid": "4350940", "title": "Tetrahydroisoquinoline alkaloids: uptake, storage, and secretion by the adrenal medulla and by adrenergic nerves.", "content": "Tetrahydroisoquinoline alkaloids: uptake, storage, and secretion by the adrenal medulla and by adrenergic nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350940"}
{"pmid": "4350941", "title": "Experimental study of sleep in chronic alcoholics before, during, and after four days of heavy drinking with a nondrinking comparison.", "content": "Experimental study of sleep in chronic alcoholics before, during, and after four days of heavy drinking with a nondrinking comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350941"}
{"pmid": "4350942", "title": "The effects of alcohol on dreams and hallucinations in alcohol addicts.", "content": "The effects of alcohol on dreams and hallucinations in alcohol addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350942"}
{"pmid": "4350943", "title": "Certain validity problems in computer analysis of clinical EEGS.", "content": "Certain validity problems in computer analysis of clinical EEGS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350943"}
{"pmid": "4350944", "title": "Electroencephalographic and other evidence for mixed depressant and stimulant actions of alcoholic beverages.", "content": "Electroencephalographic and other evidence for mixed depressant and stimulant actions of alcoholic beverages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350944"}
{"pmid": "4350945", "title": "Recent studies in man and animal of peripheral nerve and muscle dysfunction associated with chronic alcoholism.", "content": "Recent studies in man and animal of peripheral nerve and muscle dysfunction associated with chronic alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350945"}
{"pmid": "4350949", "title": "Seryl transfer ribonucleic acid synthetase of Escherichia coli B, Enzyme-substrate interactions.", "content": "Seryl transfer ribonucleic acid synthetase of Escherichia coli B, Enzyme-substrate interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350949"}
{"pmid": "4350948", "title": "Seryl transfer ribonucleic acid synthetase of Escherichia coli B. Purification, subunit structure, and behavior in the acylation reaction.", "content": "Seryl transfer ribonucleic acid synthetase of Escherichia coli B. Purification, subunit structure, and behavior in the acylation reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350948"}
{"pmid": "4350951", "title": "Two physically and functionally distinct forms of eukaryotic 40S ribosomal subunits.", "content": "Two physically and functionally distinct forms of eukaryotic 40S ribosomal subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350951"}
{"pmid": "4350950", "title": "Characterization and poly(adenylic acid) content of Ehrlich ascites cell ribonucleic acids fractionated on unmodified cellulose columns.", "content": "Characterization and poly(adenylic acid) content of Ehrlich ascites cell ribonucleic acids fractionated on unmodified cellulose columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350950"}
{"pmid": "4350953", "title": "Phospholipid biosynthesis in the membranes of immature and mature red blood cells.", "content": "Phospholipid biosynthesis in the membranes of immature and mature red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350953"}
{"pmid": "4350952", "title": "A filter assay for steroid hormone receptors.", "content": "A filter assay for steroid hormone receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350952"}
{"pmid": "4350954", "title": "Oxidation of 3,3'-diaminobenzidine by rat liver mitochondria.", "content": "Oxidation of 3,3'-diaminobenzidine by rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350954"}
{"pmid": "4350955", "title": "Lipid model membranes. Characterization of mixed phospholipid vesicles.", "content": "Lipid model membranes. Characterization of mixed phospholipid vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350955"}
{"pmid": "4350956", "title": "Thorotrast-induced hepatoma presenting as hyperparathyroidism.", "content": "Thorotrast-induced hepatoma presenting as hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350956"}
{"pmid": "4350957", "title": "Radiation-induced extraskeletal osteosarcoma.", "content": "Radiation-induced extraskeletal osteosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350957"}
{"pmid": "4350958", "title": "Ultrastructure of bronchial oncocytoma.", "content": "Ultrastructure of bronchial oncocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350958"}
{"pmid": "4350959", "title": "Structure and size prognosis in nephroblastoma.", "content": "Structure and size prognosis in nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350959"}
{"pmid": "4350960", "title": "Oat cell carcinoma of the pancreas with ectopic ACTH secretion.", "content": "Oat cell carcinoma of the pancreas with ectopic ACTH secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350960"}
{"pmid": "4350964", "title": "Cytoplasmic and mitochondrial NAD + -NADH 2  ratios in rat brain and liver: effect of hypoxia.", "content": "Cytoplasmic and mitochondrial NAD + -NADH 2  ratios in rat brain and liver: effect of hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350964"}
{"pmid": "4350965", "title": "An electrophoretic study of some hydrolases from an OP-susceptible and an OP-resistant strain of the green peach aphid, Myzus persicae (Sulz.).", "content": "An electrophoretic study of some hydrolases from an OP-susceptible and an OP-resistant strain of the green peach aphid, Myzus persicae (Sulz.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350965"}
{"pmid": "4350966", "title": "Enhancement of potassium influx, in baby hamster kidney cells and chicken erythrocytes, during adsorption of parainfluenza 1 (Sendai) virus.", "content": "Enhancement of potassium influx, in baby hamster kidney cells and chicken erythrocytes, during adsorption of parainfluenza 1 (Sendai) virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350966"}
{"pmid": "4350967", "title": "Phosphatidylinositol metabolism in cells receiving extracellular stimulation.", "content": "Phosphatidylinositol metabolism in cells receiving extracellular stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350967"}
{"pmid": "4350968", "title": "Formation of 2,3-pentanediol from 2,3-pentanedione and acetylethylcarbinol by diacetyl(acetoin)reductase from Aerobacter aerogenes. A possible new pathway.", "content": "Formation of 2,3-pentanediol from 2,3-pentanedione and acetylethylcarbinol by diacetyl(acetoin)reductase from Aerobacter aerogenes. A possible new pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350968"}
{"pmid": "4350969", "title": "DNA synthesis in isolated nuclei and isolated mitochondria of herpes simplex virus infected HeLa cells.", "content": "DNA synthesis in isolated nuclei and isolated mitochondria of herpes simplex virus infected HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350969"}
{"pmid": "4350970", "title": "Structural properties of the ligand binding sites of murine myeloma proteins.", "content": "Structural properties of the ligand binding sites of murine myeloma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350970"}
{"pmid": "4350973", "title": "Specific killing of RSV-transformed cells in vitro by lymphoid cells from RSV tumor-bearing chickens.", "content": "Specific killing of RSV-transformed cells in vitro by lymphoid cells from RSV tumor-bearing chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350973"}
{"pmid": "4350972", "title": "The variable influence of host microflora and intercurrent infections on immunological competence and carcinogenesis.", "content": "The variable influence of host microflora and intercurrent infections on immunological competence and carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350972"}
{"pmid": "4350975", "title": "Analysis of cell membrane antigens using radioiodinated, purified antibodies. II. A factor in the serum of hamsters bearing SV 40 -induced tumors which reacts with antibodies to SV 40 -transformed cell membranes.", "content": "Analysis of cell membrane antigens using radioiodinated, purified antibodies. II. A factor in the serum of hamsters bearing SV 40 -induced tumors which reacts with antibodies to SV 40 -transformed cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350975"}
{"pmid": "4350974", "title": "Analysis of cell membrane antigens using radioiodinated, purified antibodies. I. Solubilization and preliminary fractionation of membrane antigens of cells transformed by SV 40  virus.", "content": "Analysis of cell membrane antigens using radioiodinated, purified antibodies. I. Solubilization and preliminary fractionation of membrane antigens of cells transformed by SV 40  virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350974"}
{"pmid": "4350978", "title": "Nutritional effectiveness of 1,25-dihydroxycholecalciferol in preventing rickets in chicks.", "content": "Nutritional effectiveness of 1,25-dihydroxycholecalciferol in preventing rickets in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350978"}
{"pmid": "4350987", "title": "Experimental Listeria cystitis. II. Further evidence of the epithelial phase in experimental Listeria infection. An electron microscopic study.", "content": "Experimental Listeria cystitis. II. Further evidence of the epithelial phase in experimental Listeria infection. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350987"}
{"pmid": "4350986", "title": "Ultrastructure of the proximal convoluted tubules during repair following hormonally induced necrosis in rat kidney.", "content": "Ultrastructure of the proximal convoluted tubules during repair following hormonally induced necrosis in rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350986"}
{"pmid": "4350988", "title": "Histochemical and ultrastructural investigation on the endocrine cells of the stomach in hypersecreting (pylorus-ligated) rats.", "content": "Histochemical and ultrastructural investigation on the endocrine cells of the stomach in hypersecreting (pylorus-ligated) rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350988"}
{"pmid": "4350989", "title": "Primary carcinoma of the extrahepatic bile ducts.", "content": "Primary carcinoma of the extrahepatic bile ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350989"}
{"pmid": "4350990", "title": "Metastases and primary neoplasms of the stomach in patients with breast cancer.", "content": "Metastases and primary neoplasms of the stomach in patients with breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350990"}
{"pmid": "4350977", "title": "Measurement of plasma renin activity by angiotensin I radioimmunoassay. II. Clinical results.", "content": "Measurement of plasma renin activity by angiotensin I radioimmunoassay. II. Clinical results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350977"}
{"pmid": "4350993", "title": "Rabbit red cell cyclic AMP-dependent protein kinase. I. Reversible subunit interaction.", "content": "Rabbit red cell cyclic AMP-dependent protein kinase. I. Reversible subunit interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350993"}
{"pmid": "4350994", "title": "Respiratory control and oxidative phosphorylation of the cytochrome c-cytochrome oxidase complex.", "content": "Respiratory control and oxidative phosphorylation of the cytochrome c-cytochrome oxidase complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350994"}
{"pmid": "4350995", "title": "A rapid method for the isolation of large quantities of rat liver parenchymal cells with high anabolic rates.", "content": "A rapid method for the isolation of large quantities of rat liver parenchymal cells with high anabolic rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350995"}
{"pmid": "4350997", "title": "Purification of anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase from Salmonella typhimurium using affinity chromatography: resolution of monomeric and dimeric forms.", "content": "Purification of anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase from Salmonella typhimurium using affinity chromatography: resolution of monomeric and dimeric forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350997"}
{"pmid": "4350996", "title": "Cortisol receptors in rabbit fetal lung.", "content": "Cortisol receptors in rabbit fetal lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350996"}
{"pmid": "4350998", "title": "Comparison of the Ca ++  requirement for the steroidogenic effect of ACTH acid dibutyryl cyclic AMP in rat adrenal cell suspension.", "content": "Comparison of the Ca ++  requirement for the steroidogenic effect of ACTH acid dibutyryl cyclic AMP in rat adrenal cell suspension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350998"}
{"pmid": "4351000", "title": "Contribution of \"substrate shuttles\" in hepatic alcohol metabolism in chronic alcoholism.", "content": "Contribution of \"substrate shuttles\" in hepatic alcohol metabolism in chronic alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351000"}
{"pmid": "4350999", "title": "Demonstration of a glycoprotein which is associated with a purified myelin fraction from rat brain.", "content": "Demonstration of a glycoprotein which is associated with a purified myelin fraction from rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4350999"}
{"pmid": "4351001", "title": "Mitochondrial DNA and glucose repression in yeast.", "content": "Mitochondrial DNA and glucose repression in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351001"}
{"pmid": "4351002", "title": "Chain reversals in proteins.", "content": "Chain reversals in proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351002"}
{"pmid": "4351003", "title": "Mössbauer effect in bacterial catalase.", "content": "Mössbauer effect in bacterial catalase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351003"}
{"pmid": "4351004", "title": "A hydrogen-deuterium exchange study of membranous cytochrome oxidase.", "content": "A hydrogen-deuterium exchange study of membranous cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351004"}
{"pmid": "4351005", "title": "Turbidimetric estimation of chylomicrons and very low density lipoproteins in human sera after precipitation by sodium lauryl sulfate.", "content": "Turbidimetric estimation of chylomicrons and very low density lipoproteins in human sera after precipitation by sodium lauryl sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351005"}
{"pmid": "4351008", "title": "Electron microscopic evidence of the subviral oncogenic particles (virosomes) isolated from the mitochondria of Rous sarcoma cells.", "content": "Electron microscopic evidence of the subviral oncogenic particles (virosomes) isolated from the mitochondria of Rous sarcoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351008"}
{"pmid": "4351011", "title": "Status of credentialing for health personnel.", "content": "Status of credentialing for health personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351011"}
{"pmid": "4351010", "title": "The influence of in vivo administered chloramphenicol and oxytetracycline on some mitochondrial enzymes of rat-small-intestinal epithelium: histochemical data.", "content": "The influence of in vivo administered chloramphenicol and oxytetracycline on some mitochondrial enzymes of rat-small-intestinal epithelium: histochemical data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351010"}
{"pmid": "4351012", "title": "Regulation of cyclic AMP levels and aggregation in human platelets by prostaglandin E   .", "content": "Regulation of cyclic AMP levels and aggregation in human platelets by prostaglandin E   .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351012"}
{"pmid": "4351013", "title": "Monolayer cell culture of neonatal rat pancreas: an ultrastructural and biochemical study of functioning endocrine cells.", "content": "Monolayer cell culture of neonatal rat pancreas: an ultrastructural and biochemical study of functioning endocrine cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351013"}
{"pmid": "4351015", "title": "Autopsy findings in a long-surviving liver recipient.", "content": "Autopsy findings in a long-surviving liver recipient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351015"}
{"pmid": "4351014", "title": "The structures of the principal glycerolipids of pig liver.", "content": "The structures of the principal glycerolipids of pig liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351014"}
{"pmid": "4351016", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 28-1973.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 28-1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351016"}
{"pmid": "4351019", "title": "Epidemiology of slipped capital femoral epiphysis: a review of the literature.", "content": "Epidemiology of slipped capital femoral epiphysis: a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351019"}
{"pmid": "4351020", "title": "Revolutions and cyclical rhythms in prenatal life: fetal respiratory movements rediscovered.", "content": "Revolutions and cyclical rhythms in prenatal life: fetal respiratory movements rediscovered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351020"}
{"pmid": "4351024", "title": "Interstitial pneumonia and cytomegalovirus infection as complications of human marrow transplantation.", "content": "Interstitial pneumonia and cytomegalovirus infection as complications of human marrow transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351024"}
{"pmid": "4351025", "title": "A simple method for evaluating the immunosuppressive potency of antimouse lymphocytic serum.", "content": "A simple method for evaluating the immunosuppressive potency of antimouse lymphocytic serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351025"}
{"pmid": "4351032", "title": "Histological and ultrastructural studies of the basal disk of Hydra. II. Nerve cells and other epithelial cells.", "content": "Histological and ultrastructural studies of the basal disk of Hydra. II. Nerve cells and other epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351032"}
{"pmid": "4351033", "title": "Cochlear pathology in viral disease.", "content": "Cochlear pathology in viral disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351033"}
{"pmid": "4351034", "title": "Spiral ganglion virus-like particles of guinea pigs. Further observations.", "content": "Spiral ganglion virus-like particles of guinea pigs. Further observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351034"}
{"pmid": "4351035", "title": "Clinical studies in sudden deafness.", "content": "Clinical studies in sudden deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351035"}
{"pmid": "4351036", "title": "The role of viruses in sudden deafness.", "content": "The role of viruses in sudden deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351036"}
{"pmid": "4351037", "title": "Clinical measures of 8th nerve function.", "content": "Clinical measures of 8th nerve function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351037"}
{"pmid": "4351038", "title": "Behavioral studies of noise-induced hearing loss in primates: loudness recruitment.", "content": "Behavioral studies of noise-induced hearing loss in primates: loudness recruitment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351038"}
{"pmid": "4351041", "title": "Public policy toward environment 1973: a review and appraisal. The seabed.", "content": "Public policy toward environment 1973: a review and appraisal. The seabed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351041"}
{"pmid": "4351044", "title": "Thermal enhancement of DNA damage by an alkylating agent in human cells.", "content": "Thermal enhancement of DNA damage by an alkylating agent in human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351044"}
{"pmid": "4351045", "title": "The role of superoxide and singlet oxygen in lipid peroxidation promoted by xanthine oxidase.", "content": "The role of superoxide and singlet oxygen in lipid peroxidation promoted by xanthine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351045"}
{"pmid": "4351046", "title": "Resonance Raman spectroscopy of cytochrome c oxidase and electron transport particles with excitation near the Soret band.", "content": "Resonance Raman spectroscopy of cytochrome c oxidase and electron transport particles with excitation near the Soret band.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351046"}
{"pmid": "4351047", "title": "Translation of AKR-murine leukemia viral RNA in an E. coli cell-free system.", "content": "Translation of AKR-murine leukemia viral RNA in an E. coli cell-free system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351047"}
{"pmid": "4351048", "title": "Pituitary hormone releasing or inhibiting activity of metal ions present in hypothalamic extracts.", "content": "Pituitary hormone releasing or inhibiting activity of metal ions present in hypothalamic extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351048"}
{"pmid": "4351049", "title": "Action of methanol on the assocation of ribosomal subunits and its effect on the GTPase activity of elongation factor G.", "content": "Action of methanol on the assocation of ribosomal subunits and its effect on the GTPase activity of elongation factor G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351049"}
{"pmid": "4351050", "title": "CRF-stimulated biosynthesis of ACTH in a cell-free system from rat anterior pituitaries.", "content": "CRF-stimulated biosynthesis of ACTH in a cell-free system from rat anterior pituitaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351050"}
{"pmid": "4351051", "title": "Effect of pyrimidine and ribose modifications on the antiviral activity of synthetic polynucleotides.", "content": "Effect of pyrimidine and ribose modifications on the antiviral activity of synthetic polynucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351051"}
{"pmid": "4351052", "title": "Simian virus 40 rapidly lowers cAMP levels in mouse cells.", "content": "Simian virus 40 rapidly lowers cAMP levels in mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351052"}
{"pmid": "4351053", "title": "The principal glucocorticoid binding macromolecule in hepatoma cells in culture is similar to corticosteroid binder II of rat liver cytosol.", "content": "The principal glucocorticoid binding macromolecule in hepatoma cells in culture is similar to corticosteroid binder II of rat liver cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351053"}
{"pmid": "4351055", "title": "Detection of three kinetic phases in the thermal unfolding of ferricytochrome c.", "content": "Detection of three kinetic phases in the thermal unfolding of ferricytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351055"}
{"pmid": "4351054", "title": "Inhibition of ACTH-stimulated steroidogenesis in isolated rat adrenal cells treated with neuraminidase.", "content": "Inhibition of ACTH-stimulated steroidogenesis in isolated rat adrenal cells treated with neuraminidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351054"}
{"pmid": "4351056", "title": "Thermodynamic studies of the opening of the heme crevice of ferricytochrome c.", "content": "Thermodynamic studies of the opening of the heme crevice of ferricytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351056"}
{"pmid": "4351057", "title": "Effects of insulin, epinephrine, and cyclic adenosine monophosphate on pyruvate dehydrogenase of adipose tissue.", "content": "Effects of insulin, epinephrine, and cyclic adenosine monophosphate on pyruvate dehydrogenase of adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351057"}
{"pmid": "4351058", "title": "On the complexation of ferric ions by reduced nicotinamide adenine dinucleotide.", "content": "On the complexation of ferric ions by reduced nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351058"}
{"pmid": "4351059", "title": "Lateral phase separation in phospholipid membranes.", "content": "Lateral phase separation in phospholipid membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351059"}
{"pmid": "4351061", "title": "Proton spin lattice relaxation time measurements at 90MHz and 270 MHz.", "content": "Proton spin lattice relaxation time measurements at 90MHz and 270 MHz.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351061"}
{"pmid": "4351060", "title": "Amino acid sequence of a cyanogen bromide cleavage peptide from hens egg phosvitin.", "content": "Amino acid sequence of a cyanogen bromide cleavage peptide from hens egg phosvitin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351060"}
{"pmid": "4351062", "title": "Lactate dehydrogenase: electrophoretic behaviour, electron microscopy and structure.", "content": "Lactate dehydrogenase: electrophoretic behaviour, electron microscopy and structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351062"}
{"pmid": "4351063", "title": "Isolectins from wax bean with differential agglutination of normal and transformed mammalian cells.", "content": "Isolectins from wax bean with differential agglutination of normal and transformed mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351063"}
{"pmid": "4351064", "title": "Anion-binding and the state of copper in caeruloplasmin.", "content": "Anion-binding and the state of copper in caeruloplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351064"}
{"pmid": "4351066", "title": "Virological investigations in chronic prostatitis.", "content": "Virological investigations in chronic prostatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351066"}
{"pmid": "4351065", "title": "Significance of upward gaze palsy (Parinaud's syndrome) in hydrocephalus due to shunt malfunction.", "content": "Significance of upward gaze palsy (Parinaud's syndrome) in hydrocephalus due to shunt malfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351065"}
{"pmid": "4351069", "title": "Clostridia. Ubiquitous and still lethal.", "content": "Clostridia. Ubiquitous and still lethal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351069"}
{"pmid": "4351067", "title": "Synthesis of cholesterol in hypercholesterolemia and its relationship to plasma trigylcerides.", "content": "Synthesis of cholesterol in hypercholesterolemia and its relationship to plasma trigylcerides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351067"}
{"pmid": "4351074", "title": "Studies on the de novo biosynthesis of NAD in Escherichia coli. V. Properties of the quinolinic acid synthetase system.", "content": "Studies on the de novo biosynthesis of NAD in Escherichia coli. V. Properties of the quinolinic acid synthetase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351074"}
{"pmid": "4351075", "title": "Stimulation of sensitivity of the glycogen phosphorylase-converting system in skeletal muscle by metabolic inhibitors.", "content": "Stimulation of sensitivity of the glycogen phosphorylase-converting system in skeletal muscle by metabolic inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351075"}
{"pmid": "4351073", "title": "Investigation of procedures for subcellular fractionation of rabbit aortic tissue.", "content": "Investigation of procedures for subcellular fractionation of rabbit aortic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351073"}
{"pmid": "4351076", "title": "Concanavalin A as a probe of phosphomannan molecular structure.", "content": "Concanavalin A as a probe of phosphomannan molecular structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351076"}
{"pmid": "4351077", "title": "Quantum chemical study of the mechanism of collagen proline hydroxylation.", "content": "Quantum chemical study of the mechanism of collagen proline hydroxylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351077"}
{"pmid": "4351078", "title": "Factors affecting the synthesis and release of the extracellular protease of Aspergillus oryzae NRRL 2160.", "content": "Factors affecting the synthesis and release of the extracellular protease of Aspergillus oryzae NRRL 2160.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351078"}
{"pmid": "4351079", "title": "Basal and hormone-stimulated adenylate cyclase in liver plasma membranes: measurement by radioimmunoassay of cyclic AMP.", "content": "Basal and hormone-stimulated adenylate cyclase in liver plasma membranes: measurement by radioimmunoassay of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351079"}
{"pmid": "4351081", "title": "Polysaccharides of SV 40-transformed green monkey kidney cells.", "content": "Polysaccharides of SV 40-transformed green monkey kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351081"}
{"pmid": "4351082", "title": "Cerebral amino acids of rats deprived of paradoxical sleep.", "content": "Cerebral amino acids of rats deprived of paradoxical sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351082"}
{"pmid": "4351080", "title": "Cyclic nucleotide phosphodiesterase activity in the plasma and erythrocytes of normal and diabetic rats.", "content": "Cyclic nucleotide phosphodiesterase activity in the plasma and erythrocytes of normal and diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351080"}
{"pmid": "4351083", "title": "The effect of placebo and drugs on human sleep.", "content": "The effect of placebo and drugs on human sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351083"}
{"pmid": "4351084", "title": "The distribution of free myo-inositol in fluids, spermatozoa, and tissues of the bull genital tract and observations on its uptake by the rabbit epididymis.", "content": "The distribution of free myo-inositol in fluids, spermatozoa, and tissues of the bull genital tract and observations on its uptake by the rabbit epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351084"}
{"pmid": "4351086", "title": "Calcium transport through carbon tetrachloride solutions of vitamin D 3 .", "content": "Calcium transport through carbon tetrachloride solutions of vitamin D 3 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351086"}
{"pmid": "4351088", "title": "The early ambulation of patients after myocardial infarction.", "content": "The early ambulation of patients after myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351088"}
{"pmid": "4351087", "title": "Mastocalcergy in the mouse.", "content": "Mastocalcergy in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351087"}
{"pmid": "4351090", "title": "A study of the direct o-toluidine blood glucose determination.", "content": "A study of the direct o-toluidine blood glucose determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351090"}
{"pmid": "4351091", "title": "A stable plasma lipoprotein and lecithin cholesterol acyltransferase control material.", "content": "A stable plasma lipoprotein and lecithin cholesterol acyltransferase control material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351091"}
{"pmid": "4351092", "title": "Inhibitors of the growth and aggregation of calcium oxalate crystals in vitro.", "content": "Inhibitors of the growth and aggregation of calcium oxalate crystals in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351092"}
{"pmid": "4351093", "title": "Increased bone formation in rabbits following intravenous and intra-osseous injection of zinc beryllium silicate.", "content": "Increased bone formation in rabbits following intravenous and intra-osseous injection of zinc beryllium silicate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351093"}
{"pmid": "4351096", "title": "Difficulties of the differential diagnosis in a medulloblastoma. A casuistic contribution.", "content": "Difficulties of the differential diagnosis in a medulloblastoma. A casuistic contribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351096"}
{"pmid": "4351094", "title": "Glycogen metabolism in human hormone-producing trophoblastic cells in continuous culture--II. Characterization of BeWo glycogen phosphorylase.", "content": "Glycogen metabolism in human hormone-producing trophoblastic cells in continuous culture--II. Characterization of BeWo glycogen phosphorylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351094"}
{"pmid": "4351099", "title": "Metabolic oscillations and food intake.", "content": "Metabolic oscillations and food intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351099"}
{"pmid": "4351098", "title": "The adnormal biochemistry of inherited disorders of lipid metabolism.", "content": "The adnormal biochemistry of inherited disorders of lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351098"}
{"pmid": "4351100", "title": "Current enigmas in cancer research.", "content": "Current enigmas in cancer research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351100"}
{"pmid": "4351101", "title": "Genetic control of melanin metabolism within the melanin unit of mammalian epidermis.", "content": "Genetic control of melanin metabolism within the melanin unit of mammalian epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351101"}
{"pmid": "4351102", "title": "Dermatoglyphics.", "content": "Dermatoglyphics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351102"}
{"pmid": "4351103", "title": "Ophthalmologic, biochemical, platelet, and ultrastructural defects in the various types of oculocutaneous albinism.", "content": "Ophthalmologic, biochemical, platelet, and ultrastructural defects in the various types of oculocutaneous albinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351103"}
{"pmid": "4351104", "title": "The inheritance of psoriasis.", "content": "The inheritance of psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351104"}
{"pmid": "4351105", "title": "Primary glioblastoma multiforme of the spinal cord in infancy and childhood.", "content": "Primary glioblastoma multiforme of the spinal cord in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351105"}
{"pmid": "4351106", "title": "Divalent ion metabolism and the kidney.", "content": "Divalent ion metabolism and the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351106"}
{"pmid": "4351108", "title": "A possible relationship between persistent hepatitis B antigenaemia and renal disease in Southern African Bantu.", "content": "A possible relationship between persistent hepatitis B antigenaemia and renal disease in Southern African Bantu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351108"}
{"pmid": "4351107", "title": "Combination chemotherapy in the treatment of advanced Hodgkin's disease.", "content": "Combination chemotherapy in the treatment of advanced Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351107"}
{"pmid": "4351109", "title": "The paricipation of phospholipids in the extrinsic pathway of the coagulation process.", "content": "The paricipation of phospholipids in the extrinsic pathway of the coagulation process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351109"}
{"pmid": "4351095", "title": "Rhythmic heart rate variability (sinus arrhythmia) related to stages of sleep.", "content": "Rhythmic heart rate variability (sinus arrhythmia) related to stages of sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351095"}
{"pmid": "4351115", "title": "Comparison of equivalent spherical volume and aerodynamic diameters for irregularly shaped particles.", "content": "Comparison of equivalent spherical volume and aerodynamic diameters for irregularly shaped particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351115"}
{"pmid": "4351116", "title": "Oral fat tolerance studies in chronic pancreatitis.", "content": "Oral fat tolerance studies in chronic pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351116"}
{"pmid": "4351117", "title": "Gastrointestinal neuropathy in familial amyloidosis. Report of a case with severe diarrhea without steatorrhea or malabsorption.", "content": "Gastrointestinal neuropathy in familial amyloidosis. Report of a case with severe diarrhea without steatorrhea or malabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351117"}
{"pmid": "4351119", "title": "Microbiological assay of purines.", "content": "Microbiological assay of purines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351119"}
{"pmid": "4351118", "title": "A rapid and sensitive assay for pyrimidine dimers in DNA.", "content": "A rapid and sensitive assay for pyrimidine dimers in DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351118"}
{"pmid": "4351120", "title": "A method of measuring protein dry weight in solutions of unknown salt concentration and an application to lipoproteins.", "content": "A method of measuring protein dry weight in solutions of unknown salt concentration and an application to lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351120"}
{"pmid": "4351122", "title": "Recommendations concerning the use of bacterial collagenase for isolating collagen-associated molecules from tissues.", "content": "Recommendations concerning the use of bacterial collagenase for isolating collagen-associated molecules from tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351122"}
{"pmid": "4351121", "title": "A sensitive mechanized determination of ATP+ADP.", "content": "A sensitive mechanized determination of ATP+ADP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351121"}
{"pmid": "4351123", "title": "An enzymatic cycling method for nicotinamide-adenine dinucleotide with malic and alcohol dehydrogenases.", "content": "An enzymatic cycling method for nicotinamide-adenine dinucleotide with malic and alcohol dehydrogenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351123"}
{"pmid": "4351124", "title": "Autoimmune progesterone dermatitis of pregnancy.", "content": "Autoimmune progesterone dermatitis of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351124"}
{"pmid": "4351126", "title": "The quest for instant mental health.", "content": "The quest for instant mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351126"}
{"pmid": "4351125", "title": "Contraceptive conundrum. II. Hypertension.", "content": "Contraceptive conundrum. II. Hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351125"}
{"pmid": "4351132", "title": "An investigation of viral and bacterial agents associated with ovine perinatal mortality.", "content": "An investigation of viral and bacterial agents associated with ovine perinatal mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351132"}
{"pmid": "4351133", "title": "Australian exotic animal disease control plans.", "content": "Australian exotic animal disease control plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351133"}
{"pmid": "4351134", "title": "Inhibition by avidin of the ATP-Pi enchange activities associated with preparations of energy transfer factors A and A-D.", "content": "Inhibition by avidin of the ATP-Pi enchange activities associated with preparations of energy transfer factors A and A-D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351134"}
{"pmid": "4351135", "title": "Inability of detect cyclic AMP in vegetative or sporulating cells or dormant spores of Bacillus megaterium.", "content": "Inability of detect cyclic AMP in vegetative or sporulating cells or dormant spores of Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351135"}
{"pmid": "4351137", "title": "Irreversible inhibition of ribonucleotide reductase from Ehrlich tumor cells by a modulator analog.", "content": "Irreversible inhibition of ribonucleotide reductase from Ehrlich tumor cells by a modulator analog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351137"}
{"pmid": "4351136", "title": "Structure of the flavin site of Chromatium flavocytochrome c -552 .", "content": "Structure of the flavin site of Chromatium flavocytochrome c -552 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351136"}
{"pmid": "4351138", "title": "Substrate specificity of glycogen synthase phosphatase from bovine heart: action on phosphorylase a and histone.", "content": "Substrate specificity of glycogen synthase phosphatase from bovine heart: action on phosphorylase a and histone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351138"}
{"pmid": "4351139", "title": "Stability and function of mengovirus RNA in cell-free protein synthesis.", "content": "Stability and function of mengovirus RNA in cell-free protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351139"}
{"pmid": "4351140", "title": "Loss of hepatoma ribosomal RNA during warfarin therapy.", "content": "Loss of hepatoma ribosomal RNA during warfarin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351140"}
{"pmid": "4351141", "title": "The fully-active nature of synthetic and hydrolytic activities of glucose-6-phosphatase of intact nuclear membrane.", "content": "The fully-active nature of synthetic and hydrolytic activities of glucose-6-phosphatase of intact nuclear membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351141"}
{"pmid": "4351142", "title": "Glucose metabolism in mixed glioblastoma and neuroblastoma cultures.", "content": "Glucose metabolism in mixed glioblastoma and neuroblastoma cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351142"}
{"pmid": "4351143", "title": "Kinetics of poliovirus replication in HeLa cells infected by isolated RNA.", "content": "Kinetics of poliovirus replication in HeLa cells infected by isolated RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351143"}
{"pmid": "4351144", "title": "Analysis of a crosslinked peptide from calf bone collagen: evidence that hydroxylysyl glycoside participates in the crosslink.", "content": "Analysis of a crosslinked peptide from calf bone collagen: evidence that hydroxylysyl glycoside participates in the crosslink.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351144"}
{"pmid": "4351146", "title": "Kinetics of synthesis of cytochromes a and a 3  during respiratory adaptation of yeast.", "content": "Kinetics of synthesis of cytochromes a and a 3  during respiratory adaptation of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351146"}
{"pmid": "4351145", "title": "A study of transfer RNA methylation.", "content": "A study of transfer RNA methylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351145"}
{"pmid": "4351148", "title": "Rheologic hysteresis curve shape specificity of mixed lipid films.", "content": "Rheologic hysteresis curve shape specificity of mixed lipid films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351148"}
{"pmid": "4351147", "title": "K + -stimulated ATPase in purified microsomes of bullfrog oxyntic cells.", "content": "K + -stimulated ATPase in purified microsomes of bullfrog oxyntic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351147"}
{"pmid": "4351149", "title": "Pure and mixed monomolecular films of 12-nitroxide stearate.", "content": "Pure and mixed monomolecular films of 12-nitroxide stearate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351149"}
{"pmid": "4351150", "title": "SH-groups on the surface of pancreas cells involved in secretin stimulation and glucose-mediated secretion.", "content": "SH-groups on the surface of pancreas cells involved in secretin stimulation and glucose-mediated secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351150"}
{"pmid": "4351151", "title": "Effects of glucagon, 3',5'-AMP and 3',5'-GMP on ion fluxes and transmembrane potential in perfused livers of normal and adrenalectomized rats.", "content": "Effects of glucagon, 3',5'-AMP and 3',5'-GMP on ion fluxes and transmembrane potential in perfused livers of normal and adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351151"}
{"pmid": "4351152", "title": "Aminoacyl transfer RNA formation. 3. Mechanism of aminoacylation stimulated by polyamines.", "content": "Aminoacyl transfer RNA formation. 3. Mechanism of aminoacylation stimulated by polyamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351152"}
{"pmid": "4351153", "title": "Synthesis and properties of an alternating polydeoxynucleotide containing 4-thiodeoxyuridine: poly (d(A S 4 U)-d(A-S 4 U)).", "content": "Synthesis and properties of an alternating polydeoxynucleotide containing 4-thiodeoxyuridine: poly (d(A S 4 U)-d(A-S 4 U)).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351153"}
{"pmid": "4351157", "title": "Preparation and properties of phosphatidal ethanolamine from bovine white matter.", "content": "Preparation and properties of phosphatidal ethanolamine from bovine white matter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351157"}
{"pmid": "4351158", "title": "Spin labeled lipid probes in serum lipoproteins.", "content": "Spin labeled lipid probes in serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351158"}
{"pmid": "4351159", "title": "Two forms of microsomal palmitoyl-coenzyme A synthetase.", "content": "Two forms of microsomal palmitoyl-coenzyme A synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351159"}
{"pmid": "4351160", "title": "The free lipids of Brucella melitensis and Bordetella pertussis.", "content": "The free lipids of Brucella melitensis and Bordetella pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351160"}
{"pmid": "4351161", "title": "The kinetics of the redox reactions of ubiquinone related to the electron-transport activity in the respiratory chain.", "content": "The kinetics of the redox reactions of ubiquinone related to the electron-transport activity in the respiratory chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351161"}
{"pmid": "4351163", "title": "Liver scintiphotography as an index of liver abnormality.", "content": "Liver scintiphotography as an index of liver abnormality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351163"}
{"pmid": "4351164", "title": "In vivo neutron activation analysis for calcium in man.", "content": "In vivo neutron activation analysis for calcium in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351164"}
{"pmid": "4351165", "title": "Intravenous perchlorate in brain scanning: effects on choroid plexus and lesion visibility.", "content": "Intravenous perchlorate in brain scanning: effects on choroid plexus and lesion visibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351165"}
{"pmid": "4351166", "title": "Embryonal rhabdomyosarcoma of the head and neck in children.", "content": "Embryonal rhabdomyosarcoma of the head and neck in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351166"}
{"pmid": "4351169", "title": "Frequent association of IgMlambda with crystalline inclusions in chronic lymphatic leukemic lymphocytes.", "content": "Frequent association of IgMlambda with crystalline inclusions in chronic lymphatic leukemic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351169"}
{"pmid": "4351170", "title": "Herpetic manifestations.", "content": "Herpetic manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351170"}
{"pmid": "4351171", "title": "Comparison of nucleolar proteins of normal rat liver and Novikoff hepatoma ascites cells by two-dimensional polyacrylamide gel electrophoresis.", "content": "Comparison of nucleolar proteins of normal rat liver and Novikoff hepatoma ascites cells by two-dimensional polyacrylamide gel electrophoresis. A two-dimensional polyacrylamide gel electrophoresis technique is presented for separation of acid-extracted proteins of isolated nucleoli of normal rat liver and Novikoff hepatoma ascites cells. About 100 distinct protein spots were resolved. Comparison of the patterns for normal liver and Novikoff hepatoma revealed nine spots with markedly different intensities in the two patterns. Two spots were found that were unique to the normal liver pattern, and one spot was found that was unique to the hepatoma pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351171"}
{"pmid": "4351172", "title": "Genetic control of development in Volvox: isolation and characterization of morphogenetic mutants.", "content": "Genetic control of development in Volvox: isolation and characterization of morphogenetic mutants. Morphogenetic mutants of the colonial green alga, Volvox carteri f. nagariensis, were induced by chemical mutagenesis. The 68 independent mutants are classified into 12 readily identifiable phenotypes affecting various stages of asexual development. Nine of the mutants are temperature sensitive with normal development at 25 degrees and mutant development occurring at 35 degrees . Some mutant genes appear to be involved in the regulation of differentiation or the stability of the differentiated state. Other mutations occur in genes apparently responsible for structural components of dividing cells or adult colonies. Two mutants affect different aspects of the posterior-anterior polarization of the mature colony. One mutation affects a gene which acts very early in colonial development, but affects the appearance of the mature colony. The mutants isolated demonstrate the feasibility of using Volvox to study the genetic control of early steps in embryogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351172"}
{"pmid": "4351173", "title": "Sequence homology at the 5'-termini of insect messenger RNAs.", "content": "Sequence homology at the 5'-termini of insect messenger RNAs. Treatment of insect polyribosomes with 1 M KCl released a messenger ribonucleoprotein with a pronounced 16S peak. Phenol extraction resulted in a defined peak of 10S RNA, which was judged as mRNA by the following criteria: it showed specificity for binding to ribosomes, and the formation of initiation complex was dependent on protein initiation factors, GTP, mRNA, and aminoacyl-tRNA. The complex directed protein synthesis upon the addition of elongation factors. mRNA was treated with phosphatase and phosphorylated at the 5'-end with [(32)P]cyanoethylphosphate. [(32)P]mRNA was digested by T1 ribonuclease to completion and chromatographed on DEAE-cellulose. The only fragment with (32)P was 15 nucleotides long; it was treated with pancreatic ribonuclease and fingerprinted. Fractions of AC, AAC, and AAAC were found. Initiation signal AUG or GUG in these mRNAs does not begin immediately at the 5'-end and may be at a distance greater than 15 nucleotides. Alkaline hydrolysis of mRNAs labeled in vivo with [(14)C]adenosine revealed Ap and pppAp. Alkaline hydrolysis of mRNA labeled with (32)P at the 5'-terminus resulted in pAp. Hence, these results suggest that in a heterogeneous population of mRNAs from insects, all start with A and have sequence homology at the 5'-termini. This sequence may reflect the signal for RNA polymerase on the gene or may promote the binding of mRNA to ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351173"}
{"pmid": "4351174", "title": "Cell-free synthesis of procollagen: L-929 fibroblasts as a cellular model for dermatosparaxis.", "content": "Cell-free synthesis of procollagen: L-929 fibroblasts as a cellular model for dermatosparaxis. A cell-free system that actively synthesizes collagen was prepared from L-929 fibroblasts. Chromatographic and electrophoretic techniques were used to demonstrate that the only collagenous products are pro alpha(1) and pro alpha(2) chains. The collagen synthesized by the cell-free system was also compared to the collagen extracted from the cells. The cellular collagen was composed of aggregates of pro-alpha chains, while no alpha chains were found. Procollagen peptidase activity could not be detected in the cells, and the activity present in the medium was low, comparable to that in dermatosparaxic cell cultures. These properties indicate that L-929 cells may be a model system for dermatosparaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351174"}
{"pmid": "4351175", "title": "Stimulation of eukaryotic DNA-dependent RNA polymerase by protein factors.", "content": "Stimulation of eukaryotic DNA-dependent RNA polymerase by protein factors. Protein factors that stimulate DNA-dependent RNA polymerase activity in vitro have been purified from Novikoff ascites cells. These factors are not adsorbed by the diethylaminoethylcellulose column used for RNA polymerase purification and appear in the flow-through fraction. They can be fractionated into two classes by chromatography on carboxymethylcellulose. The first peak of activity elutes at 0.1 M NH(4)Cl, is stable to heat treatment of 100 degrees for 5 min, and is designated heat-stable factor; the second peak of activity elutes at 0.3 M NH(4)Cl, is heat labile, and is designated heat-labile factor. Heat-labile factor can be further resolved into two components by chromatography on phosphocellulose. The heat-stable factor and second heat-labile factor stimulate the activity of (Novikoff ascites) RNA polymerase B by several-fold, and appear to function independently. RNA synthesis is stimulated only with native DNA as a template. No stimulation of Escherichia coli RNA polymerase is observed with any of the factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351175"}
{"pmid": "4351176", "title": "Effect of insulin on the growth pattern and adenylate cyclase activity of BHK fibroblasts.", "content": "Effect of insulin on the growth pattern and adenylate cyclase activity of BHK fibroblasts. BHK 21/13 fibroblasts grown in the presence of insulin show some characteristics of a transformed strain. Cells broaden, cross each other intricately, and form colonies on both polystyrene dishes and soft agar. The effect of insulin is prevented by addition of N(6)-butyryl adenosine 3':5'-cyclic monophosphate and theophylline to the culture medium. Insulin causes a decrease in the concentration of intracellular adenosine 3':5'-cyclic monophosphate and inhibition of adenylate cyclase activity in BHK fibroblast membranes. This inhibition is observed at insulin concentrations of 0.1 nM or higher.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351176"}
{"pmid": "4351177", "title": "Orientation and motion of amphiphilic spin labels in hexagonal lipid phases.", "content": "Orientation and motion of amphiphilic spin labels in hexagonal lipid phases. The acyl chain of spin-labeled fatty acids intercalates between the lipid hydrocarbon chains in hexagonal and micellar phases with the carboxyl group anchored at the lipid water interface. The spectra are characteristic of anisotropic motion and cannot be distinguished from the spectra of these probes in lamellar dispersions. In the hexagonal and micellar phases the molecular motion of the spin label increases as it is moved further away from the carboxyl group, similar to the behavior in the lamellar phase (Jost et al. (1971) J. Mol. Biol. 59, 77-98). The similarity in packing of the acyl chains in the hexagonal and lamellar phases suggests that localized regions of hexagonal phase are compatible with a bilayer matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351177"}
{"pmid": "4351178", "title": "Pleiotypic control by adenosine 3':5'-cyclic monophosphate: a model for growth control in animal cells.", "content": "Pleiotypic control by adenosine 3':5'-cyclic monophosphate: a model for growth control in animal cells. The effects of serum deprivation on several general cellular biochemical processes (\"pleiotypic response\") related to the growth of normal fibroblasts can be mimicked by treatment of these cells with prostaglandin E(1) in the presence of serum. N(6),O(2)'-Dibutyryl adenosine 3':5'-cyclic monophosphate and theophylline inhibit the membrane transport processes without much effect on other pleiotypic reactions such as overall protein and RNA synthesis and protein degradation. The amount of intracellular cyclic AMP increases during serum starvation and returns to the initial concentration in unstarved cells when growth is initiated again upon addition of serum. Fibroblasts transformed by simian virus 40 have a lower cyclic AMP content than their untransformed parents. Serum deprivation neither increases cyclic AMP content nor significantly affects the pleiotypic reactions in transformed cells. Cycloheximide causes a decrease in cyclic AMP content of normal fibroblasts coincidentally with the ability of this inhibitor to stimulate uridine transport and slow protein degradation in cells deprived of serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351178"}
{"pmid": "4351180", "title": "Host-gene control of type-C RNA tumor virus expression and tumorigenesis in inbred mice.", "content": "Host-gene control of type-C RNA tumor virus expression and tumorigenesis in inbred mice. We analyzed the relationship of genetic factors determining the expression of endogenous type-C RNA tumor viruses and other host-gene markers to tumorigenesis. A hybridization experiment was performed with mice of strains AKR/J and C57L, the first filial (F(1)) generation hybrids, the second filial (F(2)) generation hybrids, and the backcrosses to the two parental strains. The results demonstrated a highly significant and predictable association between the expression of complete infectious virus or the viral group-specific (gs) antigen in spleens of young mice and tumorigenesis later in life. Most of the tumors were thymic leukemia and reticulum sarcoma, but other mesenchymal, as well as epithelial, tumors were also observed. Tumors occurred preferentially in gs-antigen- or virus-positive mice of all crosses; in the C57L-backcross and F(2) mice segregating for gs-antigen and virus expression, a few gs-antigen-negative mice developed reticulum cell sarcomas. At the time of their occurrence, the mice were all gs-antigen-positive, and most had virus as well.A minor effect of the major histocompatibility locus, H-2, on leukemogenesis was found in the F(2) mice. Several tumor types were also found that we have never observed in the two parental strains. Our data provide the most direct biological evidence in favor of the viral oncogene theory. Thus, from the presence or absence of expression in early life of splenic gs antigen or virus, we can predict whether or not a tumor is likely to develop later in life. These findings suggest that the genome of endogenous type-C RNA viruses is the major determinant for tumorigenesis although they provide no clues about the factors responsible for the various histological types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351180"}
{"pmid": "4351179", "title": "Determination of natural host taxonomy of RNA tumor viruses by molecular hybridization: application to RD-114, a candidate human virus.", "content": "Determination of natural host taxonomy of RNA tumor viruses by molecular hybridization: application to RD-114, a candidate human virus. The lysogenic bacteriophages and the RNA tumor viruses have in common the ability to add their genetic information to the genome of their host cells. The biological similarity extends further; data summarized here indicate that they both possess homology to the DNA of their uninfected indigenous hosts. Sharing of common sequences with normal host DNA has been established with avian, murine, feline, and primate oncornaviruses. This finding provides a method for determining the taxonomic position of the natural host of any new RNA tumor virus isolated. Application of this approach to RD-114 revealed extensive hybridization to normal cat DNA and little, if any, hybridization to human DNA. We conclude that the data assign a feline origin rather than a human origin to RD-114.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351179"}
{"pmid": "4351182", "title": "A quantitative assay for intercellular adhesion.", "content": "A quantitative assay for intercellular adhesion. Intercellular adhesion is measured by a new method based on determination of the rates of attachment of single cells to confluent cell monolayers. The procedure is simple, rapid, and reproducible. Specific and nonspecific intercellular adhesions can be quantitated and distinguished from each other, and from the adhesion to glass (or plastic). The rate of adhesion of single cells to the monolayer is characteristic of more than 80% of the single-cell population. This method, therefore, provides a means for study of the molecular basis of intercellular adhesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351182"}
{"pmid": "4351183", "title": "Conformations of diphosphopyridine coenzymes upon binding to dehydrogenases.", "content": "Conformations of diphosphopyridine coenzymes upon binding to dehydrogenases. The binding of oxidized as well as reduced coenzyme to some dehydrogenases has been studied under different concentration ratios and temperatures by nuclear magnetic resonance spectroscopy. A significant difference in the spectral behavior between DPN(+) and DPNH upon binding is interpreted in terms of fast and slow on-off rates relative to the nuclear magnetic resonance time scale in the binding of these two coenzymes. Significant downfield shifts of DPN(+) were observed upon binding, comparable in magnitude to those expected upon opening (destacking) of the coenzymes in the case of chicken-muscle and lobster-tail lactate dehydrogenase (EC 1.1.1.27) and yeast alchol dehydrogenase (EC 1.1.1.1.). A preliminary survey of several other dehydrogenases is consistent with these findings. In the case of 3-phosphoglyceraldehyde dehydrogenase, there is a possibility that the coenzyme exists in the folded form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351183"}
{"pmid": "4351181", "title": "A tumor antigen in tissue cultures derived from patients with Hodgkin's disease.", "content": "A tumor antigen in tissue cultures derived from patients with Hodgkin's disease. Pellets obtained from supernatant fluids of monolayer cultures of cells from patients with Hodgkin's disease were fractionated by isopycnic density sedimentation. Material in a peak of specific gravity 1.15-1.21 g/ml from two Hodgkin's disease cultures was used to immunize rabbits, and the antisera obtained in this manner were reacted by agar-gel diffusion and immunoelectrophoresis with antigens from the purified peaks and the unfractionated pellets of centrifuged culture medium from all the cultures. The antisera reacted with material from 9 of 10 lines derived from spleens of patients with Hodgkin's disease, 2 of 8 cell lines from histologically negative spleens from patients with Hodgkin's disease and with 3 of 6 lymphoma cell lines not diagnosed as Hodgkin's disease. The antisera did not react with 12 cell cultures prepared from normal adult and fetal spleen and thymus. The antigen from cultures from patients with Hodgkin's disease was not found in material sedimenting at lower specific gravities; it resisted Tweenether solubilization, and migrated as a single band by immunoelectrophoresis. The antigen was not found in disrupted, noncultured tumor cells from patients with Hodgkin's disease, and an antiserum against noncultured, minced tumor tissue did not react with the Hodgkin's disease tissue-culture material. No immunological relationship was found between the tissue culture antigen and Epstein-Barr, RD-114, or Rauscher murine leukemia viruses. The Hodgkin's disease antigen may be a tumorrelated antigen or a component of an oncogenic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351181"}
{"pmid": "4351184", "title": "Antigenic properties of endogenous type-C viruses from spontaneously transformed clones of BALB-3T3.", "content": "Antigenic properties of endogenous type-C viruses from spontaneously transformed clones of BALB-3T3. During long-term tissue culture of spontaneously transformed clones from BALB/c 3T3 mouse-embryo cells, some clones spontaneously begin to produce high titers of endogenous murine type-C viruses. The antigenic properties of these viruses have been analyzed by indirect immunoelectronmicroscopy and can be classified into two distinguishable populations: (a) BALB/c murine myeloma-associated extracellular viruses that carry a specific envelope antigen, xVEA, different from the typical murine leukemia viral envelope antigens; and (b) previously uncharacterized type-C viruses that have neither xVEA nor the murine leukemia viral envelope antigens. The former produces PC1 antigen and the latter might induce a new cell-surface antigen. Neither of these two populations of BALB/3T3 endogenous type-C viruses was able to infect BALB/c cells but both could infect NIH Swiss cells. A single BALB/3T3 clone, then, can release infectious endogenous type-C viruses with at least two different antigenic properties. We conclude that BALB/c somatic cells contain preexisting genetic information for production of at least closely related but, nevertheless, distinct type-C viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351184"}
{"pmid": "4351185", "title": "The fine structure of human lymph nodes under reactive conditions.", "content": "The fine structure of human lymph nodes under reactive conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351185"}
{"pmid": "4351190", "title": "Autonomic defects in paralysis agitans and in the Shy-Drager syndrome.", "content": "Autonomic defects in paralysis agitans and in the Shy-Drager syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351190"}
{"pmid": "4351192", "title": "Cerebrocerebellar pathways. Anatomical data and some functional implications.", "content": "Cerebrocerebellar pathways. Anatomical data and some functional implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351192"}
{"pmid": "4351191", "title": "Biochemical and pharmacological aspects of Parkinsonism.", "content": "Biochemical and pharmacological aspects of Parkinsonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351191"}
{"pmid": "4351193", "title": "Functional aspects of cerebellar signs in clinical neurology.", "content": "Functional aspects of cerebellar signs in clinical neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351193"}
{"pmid": "4351194", "title": "On the possible role of cyclic AMP in the neuromuscular transmission and in the treatment of myasthenia gravis.", "content": "On the possible role of cyclic AMP in the neuromuscular transmission and in the treatment of myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351194"}
{"pmid": "4351195", "title": "Polyneuropathy caused by unknown universal intracellular deposits-paraamyloidosis? Clinical, light microscopic and electron microscopic study.", "content": "Polyneuropathy caused by unknown universal intracellular deposits-paraamyloidosis? Clinical, light microscopic and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351195"}
{"pmid": "4351197", "title": "Clinical syndromes associated with EB virus infection.", "content": "Clinical syndromes associated with EB virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351197"}
{"pmid": "4351196", "title": "Clinical applications of hypothalamic-releasing factors.", "content": "Clinical applications of hypothalamic-releasing factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351196"}
{"pmid": "4351198", "title": "Viral hepatitis.", "content": "Viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351198"}
{"pmid": "4351199", "title": "Fine structure of acinar cells of human parotid gland.", "content": "Fine structure of acinar cells of human parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351199"}
{"pmid": "4351200", "title": "Metabolic activity during the degenerative and early regenerative stages of minced skeletal muscle.", "content": "Metabolic activity during the degenerative and early regenerative stages of minced skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351200"}
{"pmid": "4351201", "title": "Regional variations in endoplasmic reticulum in the vas deferens of normal and vasectomized rats.", "content": "Regional variations in endoplasmic reticulum in the vas deferens of normal and vasectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351201"}
{"pmid": "4351202", "title": "Tissue explants used for enhancement of herpesvirus isolations.", "content": "Tissue explants used for enhancement of herpesvirus isolations. Herpesvirus recovery from normal and experimentally infected simian tissues prepared into 10 to 20% homogenates was compared with that obtained by explanting these same tissues. The explant procedure was by far the more sensitive of the two methods. As a result, 8 herpesvirus isolations were obtained by conventional virus isolation procedures in contrast to 74 isolates when explants were made from these same tissue sources. There is also evidence to suggest that the explant method is more sensitive than the use of tissue homogenates for recovery of other viruses as well.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351202"}
{"pmid": "4351203", "title": "Purification and properties of yeast histidinol phosphate phosphatase.", "content": "Purification and properties of yeast histidinol phosphate phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351203"}
{"pmid": "4351205", "title": "Application of laser self-beat spectroscopic technique to the study of solutions of human plasma low-density lipoproteins.", "content": "Application of laser self-beat spectroscopic technique to the study of solutions of human plasma low-density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351205"}
{"pmid": "4351204", "title": "Adenosine 3',5'-monophosphate and protein kinase dependent phosphorylation of ribosomal protein.", "content": "Adenosine 3',5'-monophosphate and protein kinase dependent phosphorylation of ribosomal protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351204"}
{"pmid": "4351206", "title": "Electron paramagnetic resonance study of iodine-induced radicals of benzo( ) pyrene and other polycyclic hydrocarbons.", "content": "Electron paramagnetic resonance study of iodine-induced radicals of benzo( ) pyrene and other polycyclic hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351206"}
{"pmid": "4351207", "title": "Photochemical systems of Rhodospirillum rubrum. Light-induced reactions and biological functions of c-type cytochromes in relation to P-870.", "content": "Photochemical systems of Rhodospirillum rubrum. Light-induced reactions and biological functions of c-type cytochromes in relation to P-870.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351207"}
{"pmid": "4351212", "title": "Dysfunction patterns analogous to frontal lobe system and caudate nucleus syndromes in some groups of minimal brain dysfunction.", "content": "Dysfunction patterns analogous to frontal lobe system and caudate nucleus syndromes in some groups of minimal brain dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351212"}
{"pmid": "4351213", "title": "Is anatomy destiny? Panel: the changing role of women psychiatrists.", "content": "Is anatomy destiny? Panel: the changing role of women psychiatrists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351213"}
{"pmid": "4351214", "title": "New Jersey women physicians--their opinions on today's world.", "content": "New Jersey women physicians--their opinions on today's world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351214"}
{"pmid": "4351215", "title": "Clinical application of fluorescent staining of chromosomes.", "content": "Clinical application of fluorescent staining of chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351215"}
{"pmid": "4351216", "title": "Purification and properties of a mutant bifunctional enzyme from the HisB gene of Salmonella typhimurium.", "content": "Purification and properties of a mutant bifunctional enzyme from the HisB gene of Salmonella typhimurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351216"}
{"pmid": "4351217", "title": "Studies on the reconstitution of bovine erythrocyte superoxide dismutase. IV. Preparation and some properties of the enzyme in which Co(II) is substituted for Zn(II).", "content": "Studies on the reconstitution of bovine erythrocyte superoxide dismutase. IV. Preparation and some properties of the enzyme in which Co(II) is substituted for Zn(II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351217"}
{"pmid": "4351218", "title": "Assembly of the mitochondrial membrane system. IX. Purification, characterization, and subunit structure of yeast and beef cytochrome oxidase.", "content": "Assembly of the mitochondrial membrane system. IX. Purification, characterization, and subunit structure of yeast and beef cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351218"}
{"pmid": "4351219", "title": "Assembly of the mitochondrial membrane system. X. Mitochondrial synthesis of three of the subunit proteins of yeast cytochrome oxidase.", "content": "Assembly of the mitochondrial membrane system. X. Mitochondrial synthesis of three of the subunit proteins of yeast cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351219"}
{"pmid": "4351221", "title": "Interactions of 3-aminopyridine adenine dinucleotide with dehydrogenases.", "content": "Interactions of 3-aminopyridine adenine dinucleotide with dehydrogenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351221"}
{"pmid": "4351220", "title": "Binding of ( 3 H)concanavalin A to normal and transformed cells.", "content": "Binding of ( 3 H)concanavalin A to normal and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351220"}
{"pmid": "4351222", "title": "Sialidase activity in transformed cells.", "content": "Sialidase activity in transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351222"}
{"pmid": "4351223", "title": "Intraventricular septations complicating neonatal meningitis.", "content": "Intraventricular septations complicating neonatal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351223"}
{"pmid": "4351224", "title": "Metastases of glioblastoma multiforme to cervical lymph nodes. Report of two cases.", "content": "Metastases of glioblastoma multiforme to cervical lymph nodes. Report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351224"}
{"pmid": "4351232", "title": "Gastrointestinal hormones.", "content": "Gastrointestinal hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351232"}
{"pmid": "4351233", "title": "Metabolic aspects of alcohol and their biological significance.", "content": "Metabolic aspects of alcohol and their biological significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351233"}
{"pmid": "4351235", "title": "Enhanced release of dopamine  -hydroxylase and norepinephrine from sympathetic nerves by dibutyryl cyclic adenosine 3', 5'-monophosphate and theophylline.", "content": "Enhanced release of dopamine  -hydroxylase and norepinephrine from sympathetic nerves by dibutyryl cyclic adenosine 3', 5'-monophosphate and theophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351235"}
{"pmid": "4351236", "title": "The specific binding of vitamin A acid to equine liver alcohol dehydrogenase.", "content": "The specific binding of vitamin A acid to equine liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351236"}
{"pmid": "4351237", "title": "Mechanism of inactivation of rabbit muscle glyceraldehyde 3-phosphate dehydrogenase by ethacrynic acid.", "content": "Mechanism of inactivation of rabbit muscle glyceraldehyde 3-phosphate dehydrogenase by ethacrynic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351237"}
{"pmid": "4351238", "title": "Increased binding of transfer ribonucleic acid species to ribosomes under conditions interfering with their aminoacylation.", "content": "Increased binding of transfer ribonucleic acid species to ribosomes under conditions interfering with their aminoacylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351238"}
{"pmid": "4351239", "title": "Xanthoma types in relation to the type of hyperlipoproteinemia.", "content": "Xanthoma types in relation to the type of hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351239"}
{"pmid": "4351240", "title": "Acrokeratoelastoidosis mimicking palmo-plantar xanthomata.", "content": "Acrokeratoelastoidosis mimicking palmo-plantar xanthomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351240"}
{"pmid": "4351242", "title": "Experiences with the homozygous cases of familial hypercholesterolemia. A report of 52 patients.", "content": "Experiences with the homozygous cases of familial hypercholesterolemia. A report of 52 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351242"}
{"pmid": "4351241", "title": "Early diagnosis of familial type II hyperlipoproteinemia.", "content": "Early diagnosis of familial type II hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351241"}
{"pmid": "4351244", "title": "The role of altered vascular permeability in the induction of experimental xanthomata.", "content": "The role of altered vascular permeability in the induction of experimental xanthomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351244"}
{"pmid": "4351243", "title": "Atherosclerosis of heart valves and the formation of the corneal arcus as models for the study of atherosclerosis.", "content": "Atherosclerosis of heart valves and the formation of the corneal arcus as models for the study of atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351243"}
{"pmid": "4351245", "title": "Advances in lipoprotein research. Biochemical and clinical aspects.", "content": "Advances in lipoprotein research. Biochemical and clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351245"}
{"pmid": "4351250", "title": "Endocrine profile of a specific prolactin inhibitor: Br-ergocryptine (CB 154). A preliminary report.", "content": "Endocrine profile of a specific prolactin inhibitor: Br-ergocryptine (CB 154). A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351250"}
{"pmid": "4351254", "title": "The problem-oriented medical synopsis. Applications to patient care, education, and research.", "content": "The problem-oriented medical synopsis. Applications to patient care, education, and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351254"}
{"pmid": "4351255", "title": "The lysosome: a role in disease.", "content": "The lysosome: a role in disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351255"}
{"pmid": "4351256", "title": "Mechanisms of the crystal deposition diseases--gout and pseudogout.", "content": "Mechanisms of the crystal deposition diseases--gout and pseudogout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351256"}
{"pmid": "4351258", "title": "Inositol dehydrogenase from the yeast Cryptococcus melibiosum.", "content": "Inositol dehydrogenase from the yeast Cryptococcus melibiosum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351258"}
{"pmid": "4351257", "title": "Hereditary sensory neuropathy, type II. Clinical, electrophysiologic, histologic, and biochemical studies of a Quebec kinship.", "content": "Hereditary sensory neuropathy, type II. Clinical, electrophysiologic, histologic, and biochemical studies of a Quebec kinship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351257"}
{"pmid": "4351259", "title": "Evidence for the existence of lactate dehydrogenase X in embryonic chick liver.", "content": "Evidence for the existence of lactate dehydrogenase X in embryonic chick liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351259"}
{"pmid": "4351260", "title": "The ratio of type-I and -2 Cu(II) in human ceruloplasmin.", "content": "The ratio of type-I and -2 Cu(II) in human ceruloplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351260"}
{"pmid": "4351261", "title": "Specificity and mode of action of acid carboxypeptidase from Aspergillus saitoi.", "content": "Specificity and mode of action of acid carboxypeptidase from Aspergillus saitoi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351261"}
{"pmid": "4351262", "title": "Inhibition of homogeneous angiotensin-converting enzyme of rabbit lung by synthetic venom peptides of Bothrops jararaca.", "content": "Inhibition of homogeneous angiotensin-converting enzyme of rabbit lung by synthetic venom peptides of Bothrops jararaca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351262"}
{"pmid": "4351263", "title": "Multiple thoracic nodules in a young asymptomatic woman.", "content": "Multiple thoracic nodules in a young asymptomatic woman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351263"}
{"pmid": "4351264", "title": "Karyological analysis of Rous sarcoma virus-producing rat-kangaroo cell lines.", "content": "Karyological analysis of Rous sarcoma virus-producing rat-kangaroo cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351264"}
{"pmid": "4351267", "title": "Determination of anionic surfactants in water.", "content": "Determination of anionic surfactants in water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351267"}
{"pmid": "4351268", "title": "Determination of particulate phosphorus by alkaline persulfate digestion.", "content": "Determination of particulate phosphorus by alkaline persulfate digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351268"}
{"pmid": "4351269", "title": "Analysis of chlorinated aromatic hydrocarbons by exhaustive chlorination: qualitative and structural aspects of the perchloro-derivatives of biphenyl, naphthalene, terphenyl, dibenzofuran, dibenzodioxin and DDE.", "content": "Analysis of chlorinated aromatic hydrocarbons by exhaustive chlorination: qualitative and structural aspects of the perchloro-derivatives of biphenyl, naphthalene, terphenyl, dibenzofuran, dibenzodioxin and DDE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351269"}
{"pmid": "4351266", "title": "Sleep continuity changes in depression.", "content": "Sleep continuity changes in depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351266"}
{"pmid": "4351282", "title": "A rapid in vivo test for chromosomal damage.", "content": "A rapid in vivo test for chromosomal damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351282"}
{"pmid": "4351283", "title": "The mechanism of action of tetanus toxin: effect on synaptic processes and some particular features of toxin binding by the nervous tissue.", "content": "The mechanism of action of tetanus toxin: effect on synaptic processes and some particular features of toxin binding by the nervous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351283"}
{"pmid": "4351285", "title": "Local tetanus in cats: the influence of neuromuscular activity on spinal distribution of  125 I labelled tetanus toxin.", "content": "Local tetanus in cats: the influence of neuromuscular activity on spinal distribution of  125 I labelled tetanus toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351285"}
{"pmid": "4351284", "title": "A note on the specific fixation, specific deactivation and non-specific inactivation of bacterial toxins by gangliosides.", "content": "A note on the specific fixation, specific deactivation and non-specific inactivation of bacterial toxins by gangliosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351284"}
{"pmid": "4351286", "title": "Vagal ascent and distribution of  125 I-tetanus toxin after injection into the anterior wall of the stomach.", "content": "Vagal ascent and distribution of  125 I-tetanus toxin after injection into the anterior wall of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351286"}
{"pmid": "4351293", "title": "Ultrastructural changes in the coronet cells of the saccus vasculosus from rainbow trout, Salmo gairdneri (Richardson), kept in sea water.", "content": "Ultrastructural changes in the coronet cells of the saccus vasculosus from rainbow trout, Salmo gairdneri (Richardson), kept in sea water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351293"}
{"pmid": "4351295", "title": "Prejunctional depressant actions of strychnine on soleus neurotransmission in the cat.", "content": "Prejunctional depressant actions of strychnine on soleus neurotransmission in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351295"}
{"pmid": "4351297", "title": "Energy metabolism of working muscle: concentration profiles of selected metabolites.", "content": "Energy metabolism of working muscle: concentration profiles of selected metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351297"}
{"pmid": "4351296", "title": "Sodium depletion and postcaval vein constriction on steroid secretion in the bullfrog.", "content": "Sodium depletion and postcaval vein constriction on steroid secretion in the bullfrog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351296"}
{"pmid": "4351298", "title": "Specific stimulation and inhibition of renal prostaglandin release by angiotensin analogs.", "content": "Specific stimulation and inhibition of renal prostaglandin release by angiotensin analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351298"}
{"pmid": "4351302", "title": "Differences in macromolecular binding between cyclic AMP and its dibutyryl derivative in vitro.", "content": "Differences in macromolecular binding between cyclic AMP and its dibutyryl derivative in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351302"}
{"pmid": "4351301", "title": "Cyclic-3', 5'-AMP-dependent and independent protein kinase levels in normal and feline sarcoma virus transformed cells.", "content": "Cyclic-3', 5'-AMP-dependent and independent protein kinase levels in normal and feline sarcoma virus transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351301"}
{"pmid": "4351303", "title": "Effects of lipids on cyclic-nucleotide phosphodiesterases.", "content": "Effects of lipids on cyclic-nucleotide phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351303"}
{"pmid": "4351304", "title": "A novel nucleolytic activity associated with rabbit liver tRNA nucleotidyltransferase.", "content": "A novel nucleolytic activity associated with rabbit liver tRNA nucleotidyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351304"}
{"pmid": "4351305", "title": "In vitro activation of leukocyte glycogen synthetase.", "content": "In vitro activation of leukocyte glycogen synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351305"}
{"pmid": "4351306", "title": "Storage cells of spleen and bone marrow in thalassemia: an ultrastructural study.", "content": "Storage cells of spleen and bone marrow in thalassemia: an ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351306"}
{"pmid": "4351307", "title": "Recurrent Kaposi's varicelliform eruption in Darier's disease.", "content": "Recurrent Kaposi's varicelliform eruption in Darier's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351307"}
{"pmid": "4351308", "title": "Steroidogenesis and RNA synthesis in rat adrenal gland in vitro.", "content": "Steroidogenesis and RNA synthesis in rat adrenal gland in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351308"}
{"pmid": "4351309", "title": "Effect of LH on steroidogenesis and cyclic AMP accumulation in rat Leydig cell preparations and mouse tumor Leydig cells.", "content": "Effect of LH on steroidogenesis and cyclic AMP accumulation in rat Leydig cell preparations and mouse tumor Leydig cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351309"}
{"pmid": "4351299", "title": "Carcinoma of the sphenoid sinus.", "content": "Carcinoma of the sphenoid sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351299"}
{"pmid": "4351311", "title": "Plasma LH changes following cortical spreading depression in female rats.", "content": "Plasma LH changes following cortical spreading depression in female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351311"}
{"pmid": "4351310", "title": "Plasma growth hormone in the anesthetized rat. Effects of dibutyryl cyclic AMP, prostaglandin E 1 , adrenergic agents, vasopressin, chlorpromazine, amphetamine and L-dopa.", "content": "Plasma growth hormone in the anesthetized rat. Effects of dibutyryl cyclic AMP, prostaglandin E 1 , adrenergic agents, vasopressin, chlorpromazine, amphetamine and L-dopa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351310"}
{"pmid": "4351312", "title": "Interaction of growth hormone and ACTH in the regulation of adrenocortical secretion in rats.", "content": "Interaction of growth hormone and ACTH in the regulation of adrenocortical secretion in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351312"}
{"pmid": "4351313", "title": "The action of a human uterine protease on the estrogen receptor.", "content": "The action of a human uterine protease on the estrogen receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351313"}
{"pmid": "4351314", "title": "Mechanism of action of gonadotropin. 3. Binding of adenosine 3',5'-monophosphate by the 105,000 X g supernatant fraction from homogenates of calf ovaries.", "content": "Mechanism of action of gonadotropin. 3. Binding of adenosine 3',5'-monophosphate by the 105,000 X g supernatant fraction from homogenates of calf ovaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351314"}
{"pmid": "4351315", "title": "TRF and thyroid hormones on prolactin secretion by rat anterior pituitary cells in vitro.", "content": "TRF and thyroid hormones on prolactin secretion by rat anterior pituitary cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351315"}
{"pmid": "4351316", "title": "Stimulation of cyclic AMP accumulation in rat ovaries in vitro.", "content": "Stimulation of cyclic AMP accumulation in rat ovaries in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351316"}
{"pmid": "4351317", "title": "Potentiation by angiotensin II of the vasopressin response to an increasing plasma osmolality.", "content": "Potentiation by angiotensin II of the vasopressin response to an increasing plasma osmolality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351317"}
{"pmid": "4351318", "title": "Intranuclear receptor for androgens in rat epididymis.", "content": "Intranuclear receptor for androgens in rat epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351318"}
{"pmid": "4351319", "title": "Minimal O 2  consumption as an index of thyroid status: standardization of method.", "content": "Minimal O 2  consumption as an index of thyroid status: standardization of method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351319"}
{"pmid": "4351320", "title": "Progesterone and corticosterone binding in rabbit uterine cytosols.", "content": "Progesterone and corticosterone binding in rabbit uterine cytosols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351320"}
{"pmid": "4351323", "title": "Goat-pox: an anthropozoonosis.", "content": "Goat-pox: an anthropozoonosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351323"}
{"pmid": "4351324", "title": "Evoked cortical potentials in experimental spinal cord trauma.", "content": "Evoked cortical potentials in experimental spinal cord trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351324"}
{"pmid": "4351327", "title": "Subacute cerebellar degeneration and Eaton-Lambert syndrome with bronchogenic carcinoma. A case report.", "content": "Subacute cerebellar degeneration and Eaton-Lambert syndrome with bronchogenic carcinoma. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351327"}
{"pmid": "4351329", "title": "A pleomorphic adenoma (so-called mixed tumor) in the wall of a dentigerous cyst.", "content": "A pleomorphic adenoma (so-called mixed tumor) in the wall of a dentigerous cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351329"}
{"pmid": "4351328", "title": "Rod (nemaline) bodies in the skeletal muscle of an acute schizophrenic patient.", "content": "Rod (nemaline) bodies in the skeletal muscle of an acute schizophrenic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351328"}
{"pmid": "4351331", "title": "Considerations on the correlation between the blood groups and the incidence of cerebral tumours.", "content": "Considerations on the correlation between the blood groups and the incidence of cerebral tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351331"}
{"pmid": "4351341", "title": "A study of the relationship of reticuloendotheliosis virus to the avian leukosis-sarcoma complex of viruses.", "content": "A study of the relationship of reticuloendotheliosis virus to the avian leukosis-sarcoma complex of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351341"}
{"pmid": "4351342", "title": "A temperature-sensitive mutant of Rous sarcoma virus that is defective for replication.", "content": "A temperature-sensitive mutant of Rous sarcoma virus that is defective for replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351342"}
{"pmid": "4351343", "title": "Studies on the mechanism of neuromuscular transmission in insects. The effect of glutamic acid.", "content": "Studies on the mechanism of neuromuscular transmission in insects. The effect of glutamic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351343"}
{"pmid": "4351344", "title": "Two different activities of alkaline phosphatase in cultured mammalian cells.", "content": "Two different activities of alkaline phosphatase in cultured mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351344"}
{"pmid": "4351345", "title": "The purification of pig vitamin D-induced intestinal calcium binding protein.", "content": "The purification of pig vitamin D-induced intestinal calcium binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351345"}
{"pmid": "4351346", "title": "Studies on phosphodiesterase from oxyntic cells of bullfrog gastric mucosa. I. Intracellular localization, partial purification, and properties.", "content": "Studies on phosphodiesterase from oxyntic cells of bullfrog gastric mucosa. I. Intracellular localization, partial purification, and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351346"}
{"pmid": "4351347", "title": "Vitamin D 3 -25-hydroxylase: tissue occurrence and apparent lack of regulation.", "content": "Vitamin D 3 -25-hydroxylase: tissue occurrence and apparent lack of regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351347"}
{"pmid": "4351348", "title": "Covalent attachment of fluorescent groups to the 5'-end of transfer RNA.", "content": "Covalent attachment of fluorescent groups to the 5'-end of transfer RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351348"}
{"pmid": "4351350", "title": "Effect of osmolality and phosphate, 'tris', 'tes', 'mes', and 'hepes' hydrogen ion buffers on the motility of bull spermatozoa stored at 37 or 5 degreesC.", "content": "Effect of osmolality and phosphate, 'tris', 'tes', 'mes', and 'hepes' hydrogen ion buffers on the motility of bull spermatozoa stored at 37 or 5 degreesC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351350"}
{"pmid": "4351349", "title": "A rate-zonal centrifugation procedure for screening particle populations by sequential product recovery utilizing edge-unloading zonal rotors.", "content": "A rate-zonal centrifugation procedure for screening particle populations by sequential product recovery utilizing edge-unloading zonal rotors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351349"}
{"pmid": "4351351", "title": "A polymeric form of haemoglobin-binding protein in sheep following metabolic and hormonal disturbance.", "content": "A polymeric form of haemoglobin-binding protein in sheep following metabolic and hormonal disturbance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351351"}
{"pmid": "4351352", "title": "Sudden and unexpected deaths in infants: histology and virology.", "content": "Sudden and unexpected deaths in infants: histology and virology. The histological appearance of lungs of children whose death had been sudden and unexpected has been studied in relation with the viruses found at necropsy. Fifty-one children were investigated and in 33 the lungs had the histological appearance widely accepted as characteristic of the condition previously termed \"cot death.\" Sixteen had the histological appearance of lymphocytic bronchiolitis, and it was from this group only that viruses were isolated. The viruses isolated were those associated with respiratory infections. Two patients showed the histological appearance of bacterial bronchopneumonia. Viruses are probably responsible for a substantial proportion of unexpected sudden deaths in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351352"}
{"pmid": "4351353", "title": "Actinomycin D for Wilm's tumour.", "content": "Actinomycin D for Wilm's tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351353"}
{"pmid": "4351354", "title": "Antibiotic sensitivity of Clostridium perfringens and L-forms of C. perfringens induced by bacteriocin.", "content": "Antibiotic sensitivity of Clostridium perfringens and L-forms of C. perfringens induced by bacteriocin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351354"}
{"pmid": "4351355", "title": "Radioimmunoassay. Practices and pitfalls.", "content": "Radioimmunoassay. Practices and pitfalls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351355"}
{"pmid": "4351356", "title": "Use of angiotensin II antagonists in experimental hypertension.", "content": "Use of angiotensin II antagonists in experimental hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351356"}
{"pmid": "4351358", "title": "Importance of potassium in the regulation of aldosterone production.", "content": "Importance of potassium in the regulation of aldosterone production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351358"}
{"pmid": "4351357", "title": "Effects of a specific competitive antagonist of angiotensin II on arterial pressure and adrenal steroid secretion in dogs.", "content": "Effects of a specific competitive antagonist of angiotensin II on arterial pressure and adrenal steroid secretion in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351357"}
{"pmid": "4351359", "title": "Physiological receptors as physicochemical entities.", "content": "Physiological receptors as physicochemical entities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351359"}
{"pmid": "4351360", "title": "A model of the human circulation. Regulation by autonomic nervous system and renin-angiotensin system, and influence of blood volume on cardiac output and blood pressure.", "content": "A model of the human circulation. Regulation by autonomic nervous system and renin-angiotensin system, and influence of blood volume on cardiac output and blood pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351360"}
{"pmid": "4351362", "title": "Kinetic colorimetric measurement of serum lactate dehydrogenase activity.", "content": "Kinetic colorimetric measurement of serum lactate dehydrogenase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351362"}
{"pmid": "4351361", "title": "Simultaneous competitive protein binding assay for cortissol, cortisone, and prednisolone in plasma, and its clinical application.", "content": "Simultaneous competitive protein binding assay for cortissol, cortisone, and prednisolone in plasma, and its clinical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351361"}
{"pmid": "4351363", "title": "Hippocampal epilepsy produced by ouabain. Studies of cerebral circulation and ionic metabolism.", "content": "Hippocampal epilepsy produced by ouabain. Studies of cerebral circulation and ionic metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351363"}
{"pmid": "4351364", "title": "Relationship of epithelial membrane potentials to corneal potential.", "content": "Relationship of epithelial membrane potentials to corneal potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351364"}
{"pmid": "4351365", "title": "Ion pumps in the cornea and their stimulation by epinephrine and cyclic-AMP.", "content": "Ion pumps in the cornea and their stimulation by epinephrine and cyclic-AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351365"}
{"pmid": "4351368", "title": "Lungfishes and amphibians: endocrine adaptation and the transition from aquatic to terrestrial life.", "content": "Lungfishes and amphibians: endocrine adaptation and the transition from aquatic to terrestrial life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351368"}
{"pmid": "4351369", "title": "Prolactin and osmoregulation in fishes.", "content": "Prolactin and osmoregulation in fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351369"}
{"pmid": "4351367", "title": "Regulation of electrolyte balance in marine birds with special reference to the role of the pituitary-adrenal axis in the duck (Anas platyrhynchos).", "content": "Regulation of electrolyte balance in marine birds with special reference to the role of the pituitary-adrenal axis in the duck (Anas platyrhynchos).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351367"}
{"pmid": "4351378", "title": "Electron spin resonance studies on aqueous methylene blue solutions.", "content": "Electron spin resonance studies on aqueous methylene blue solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351378"}
{"pmid": "4351380", "title": "Maori art and pseudo-hypoparathyroidism--a medical contribution to prehistoric anthropology.", "content": "Maori art and pseudo-hypoparathyroidism--a medical contribution to prehistoric anthropology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351380"}
{"pmid": "4351381", "title": "Treatment of oral syndrome obesity with non-traditional appetite control plan.", "content": "Treatment of oral syndrome obesity with non-traditional appetite control plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351381"}
{"pmid": "4351370", "title": "Herpesviruses and cancer: introduction.", "content": "Herpesviruses and cancer: introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351370"}
{"pmid": "4351382", "title": "Bone case of the month.", "content": "Bone case of the month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351382"}
{"pmid": "4351383", "title": "Day care: Pandora's box?", "content": "Day care: Pandora's box?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351383"}
{"pmid": "4351384", "title": "Role of cyclic adenosine 3',5'-monophosphate in the in vivo expression of the galactose operon of Escherichia coli.", "content": "Role of cyclic adenosine 3',5'-monophosphate in the in vivo expression of the galactose operon of Escherichia coli. Studies of levels of galactokinase in Escherichia coli with mutations affecting synthesis of, or response to, cyclic adenosine 3',5'-monophosphate show that this nucleotide does not play a major role in expression of the galactose operon, causing at most a twofold stimulation. The discrepancy between our in vivo results and the marked stimulation by cyclic adenosine 3',5'-monophosphate in in vitro systems indicates that current cell-free systems lack a factor which allows efficient expression of the galactose operon even in the absence of cyclic adenosine 3',5'-monophosphate or of the binding protein for this nucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351384"}
{"pmid": "4351386", "title": "Cyclic adenosine 3',5'-monophosphate in Escherichia coli.", "content": "Cyclic adenosine 3',5'-monophosphate in Escherichia coli. The concentration of cyclic adenosine 3',5'-monophosphate (c-AMP) in Escherichia coli growing on different sources of carbon was studied. Cultures utilizing a source of carbon that supported growth relatively poorly had consistently higher concentrations of c-AMP than did cultures utilizing sugars that supported rapid growth. This relationship was also observed in strains defective in c-AMP phosphodiesterase and simultaneously resistant to catabolite repression; in such strains the c-AMP concentration was slightly higher for several sources of carbon tested. Cultures continued to synthesize c-AMP and secreted it into the medium, under conditions that brought about an inhibition of the intracellular accumulation of the cyclic nucleotide. Transient repression of the synthesis of beta-galactosidase was not associated with an abrupt decrease in the cellular concentration of c-AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351386"}
{"pmid": "4351385", "title": "Genetic mutations affecting the respiratory electron-transport system of the photosynthetic bacterium Rhodopseudomonas capsulata.", "content": "Genetic mutations affecting the respiratory electron-transport system of the photosynthetic bacterium Rhodopseudomonas capsulata. Alternative energy-converting systems permit the nonsulfur purple photosynthetic bacterium Rhodopseudomonas capsulata to grow either with light or (dark) respiration as the source of energy. Respiratory mutants, unable to grow aerobically in darkness, can be readily isolated and the defective step(s) in their respiratory mechanisms can be identified by study of biochemical activities in membrane fragments derived from photosynthetically grown cells. Such analysis of appropriate mutants and revertants permits construction of a model for the respiratory electron-transport system of the wild type. The results obtained indicate differential channeling of electrons derived from succinate and reduced nicotinamide adenine dinucleotide, and are interpreted in terms of a branched electron-transport scheme. The scheme provides a guide for further, more refined analysis of the respiratory mechanisms through biochemical genetic approaches, and several of the mutants isolated can be exploited for investigation of unsolved problems relating to interactions between respiratory and photosynthetic electron transport and the mechanism of inhibition of bacteriochlorophyll synthesis by molecular oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351385"}
{"pmid": "4351371", "title": "Herpesvirus and the frog renal adenocarcinoma.", "content": "Herpesvirus and the frog renal adenocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351371"}
{"pmid": "4351373", "title": "Herpesviruses saimiri and ateles--their role in malignant lymphomas of monkeys.", "content": "Herpesviruses saimiri and ateles--their role in malignant lymphomas of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351373"}
{"pmid": "4351374", "title": "Possible role of Herpesvirus hominis, type 2, in human cervical cancer.", "content": "Possible role of Herpesvirus hominis, type 2, in human cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351374"}
{"pmid": "4351375", "title": "In vitro cell transformation by herpesviruses.", "content": "In vitro cell transformation by herpesviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351375"}
{"pmid": "4351372", "title": "Role of herpesviruses in malignant lymphoma in rabbits.", "content": "Role of herpesviruses in malignant lymphoma in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351372"}
{"pmid": "4351388", "title": "Isolation and characterization of plasmid deoxyribonucleic acid from Streptococcus mutans.", "content": "Isolation and characterization of plasmid deoxyribonucleic acid from Streptococcus mutans. A small plasmid with a molecular weight of approximately 3.0 x 10(6) and present to the extent of about 16 copies per chromosomal genome equivalent was isolated from Streptococcus mutans strain LM-7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351388"}
{"pmid": "4351377", "title": "Role of Epstein-Barr virus in infectious mononucleosis and malignant lymphomas in man.", "content": "Role of Epstein-Barr virus in infectious mononucleosis and malignant lymphomas in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351377"}
{"pmid": "4351387", "title": "Glucose fermentation products in Ruminococcus albus grown in continuous culture with Vibrio succinogenes: changes caused by interspecies transfer of H 2 .", "content": "Glucose fermentation products in Ruminococcus albus grown in continuous culture with Vibrio succinogenes: changes caused by interspecies transfer of H 2 . The influence of a H(2)-utilizing organism, Vibrio succinogenes, on the fermentation of limiting amounts of glucose by a carbohydrate-fermenting, H(2)-producing organism, Ruminococcus albus, was studied in continuous cultures. Growth of V. succinogenes depended on the production of H(2) from glucose by R. albus. V. succinogenes used the H(2) produced by R. albus to obtain energy for growth by reducing fumarate in the medium. Fumarate was not metabolized by R. albus alone. The only products detected in continuous cultures of R. albus alone were acetate, ethanol, and H(2). CO(2) was not measured. The only products detected in the mixed cultures were acetate and succinate. No free H(2) was produced. No formate or any other volatile fatty acid, no succinate or other dicarboxylic acids, lactate, alcohols other than ethanol, pyruvate, or other keto-acids, acetoin, or diacetyl were detected in cultures of R. albus alone or in mixed cultures. The moles of product per 100 mol of glucose fermented were approximately 69 for ethanol, 74 for acetate, 237 for H(2) for R. albus alone and 147 for acetate and 384 for succinate for the mixed culture. Each mole of succinate is equivalent to the production of 1 mol of H(2) by R. albus. Thus, in the mixed cultures, ethanol production by R. albus is eliminated with a corresponding increase in acetate and H(2) formation. The mixed-culture pattern is consistent with the hypothesis that nicotinamide adenine dinucleotide (reduced form), formed during glycolysis by R. albus, is reoxidized during ethanol formation when R. albus is grown alone and is reoxidized by conversion to nicotinamide adenine dinucleotide and H(2) when R. albus is grown with V. succinogenes. The ecological significance of this interspecies transfer of H(2) gas and the theoretical basis for its causing changes in fermentation patterns of R. albus are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351387"}
{"pmid": "4351389", "title": "Purinergic autonomic neurones.", "content": "Purinergic autonomic neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351389"}
{"pmid": "4351376", "title": "Biochemical transformation of L-cells with ultraviolet-irradiated herpes simplex virus.", "content": "Biochemical transformation of L-cells with ultraviolet-irradiated herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351376"}
{"pmid": "4351391", "title": "Comparative study of two RD 114 virus-indicator cell lines, KC and KB.", "content": "Comparative study of two RD 114 virus-indicator cell lines, KC and KB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351391"}
{"pmid": "4351390", "title": "Enzymes in bovine milk: a review.", "content": "Enzymes in bovine milk: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351390"}
{"pmid": "4351392", "title": "Patterns of antibodies to Epstein-Barr virus-induced early antigens in Burkitt's lymphoma. Comparison of dying patients with long-term survivors.", "content": "Patterns of antibodies to Epstein-Barr virus-induced early antigens in Burkitt's lymphoma. Comparison of dying patients with long-term survivors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351392"}
{"pmid": "4351394", "title": "Spontaneous tumors in C3H-A vy  and C3H-A vy fB mice: high incidence in the United States and low incidence in Australia.", "content": "Spontaneous tumors in C3H-A vy  and C3H-A vy fB mice: high incidence in the United States and low incidence in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351394"}
{"pmid": "4351393", "title": "Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1  hybrids.", "content": "Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1  hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351393"}
{"pmid": "4351395", "title": "Lysis of tumor cells by antibody and complement. 1. Lack of correlation between antigen content and lytic susceptibility.", "content": "Lysis of tumor cells by antibody and complement. 1. Lack of correlation between antigen content and lytic susceptibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351395"}
{"pmid": "4351397", "title": "Induction of lymphocytic leukemia, lymphosarcoma, reticulum cell sarcoma, and osteogenic sarcoma in the Syrian golden hamster by oncogenic DNA simian virus 40.", "content": "Induction of lymphocytic leukemia, lymphosarcoma, reticulum cell sarcoma, and osteogenic sarcoma in the Syrian golden hamster by oncogenic DNA simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351397"}
{"pmid": "4351398", "title": "Carcinoembryonic antigen in normal human saliva.", "content": "Carcinoembryonic antigen in normal human saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351398"}
{"pmid": "4351396", "title": "Thymic dependency of tumor-induced immunodepression.", "content": "Thymic dependency of tumor-induced immunodepression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351396"}
{"pmid": "4351399", "title": "Adjuvants for a tumor-specific vaccine: Bordetella pertussis or mycobacterial cell walls attached to oil droplets.", "content": "Adjuvants for a tumor-specific vaccine: Bordetella pertussis or mycobacterial cell walls attached to oil droplets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351399"}
{"pmid": "4351400", "title": "Immunosuppression and experimental lymphoma.", "content": "Immunosuppression and experimental lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351400"}
{"pmid": "4351401", "title": "4-Methanesulfonyloxybutanol: hydrolysis of busulfan.", "content": "4-Methanesulfonyloxybutanol: hydrolysis of busulfan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351401"}
{"pmid": "4351402", "title": "Electrophysiologic effects of diphenidol in isolated cardiac tissue.", "content": "Electrophysiologic effects of diphenidol in isolated cardiac tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351402"}
{"pmid": "4351403", "title": "Blockade of adrenergic potentiating effect of angiotensin by 1-Sar-8-Ala-angiotensin II.", "content": "Blockade of adrenergic potentiating effect of angiotensin by 1-Sar-8-Ala-angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351403"}
{"pmid": "4351404", "title": "Pharmacology of cyanate. II. Effects on the endocrine system.", "content": "Pharmacology of cyanate. II. Effects on the endocrine system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351404"}
{"pmid": "4351406", "title": "Heredity and cancer in man.", "content": "Heredity and cancer in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351406"}
{"pmid": "4351410", "title": "The funding crisis: an opportunity for growth.", "content": "The funding crisis: an opportunity for growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351410"}
{"pmid": "4351407", "title": "The familial dyslipoproteinemias.", "content": "The familial dyslipoproteinemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351407"}
{"pmid": "4351411", "title": "The background and promise of tumor virology, immunology, and chemotherapy and a challenge to radiotherapy. Janeway Memorial lecture.", "content": "The background and promise of tumor virology, immunology, and chemotherapy and a challenge to radiotherapy. Janeway Memorial lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351411"}
{"pmid": "4351412", "title": "Reliability of skeletal age assessments.", "content": "Reliability of skeletal age assessments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351412"}
{"pmid": "4351413", "title": "The enlarge foramen ovale.", "content": "The enlarge foramen ovale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351413"}
{"pmid": "4351415", "title": "Simple vulvectomy--a 10-year review.", "content": "Simple vulvectomy--a 10-year review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351415"}
{"pmid": "4351414", "title": "Immune response in families of children with acute lymphoblastic leukaemia.", "content": "Immune response in families of children with acute lymphoblastic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351414"}
{"pmid": "4351423", "title": "Effect of ADP-induced aggregation on  32 PO 4  incorporation into phosphatidic acid and the phosphoinositides of rabbit platelets.", "content": "Effect of ADP-induced aggregation on  32 PO 4  incorporation into phosphatidic acid and the phosphoinositides of rabbit platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351423"}
{"pmid": "4351422", "title": "The role of dermal blood vessels in the pathogenesis of malignant atrophic papulosis (Degos' disease). A study of two cases using enzyme histochemical, fibrinolytic, electron-microscopical and immunological techniques.", "content": "The role of dermal blood vessels in the pathogenesis of malignant atrophic papulosis (Degos' disease). A study of two cases using enzyme histochemical, fibrinolytic, electron-microscopical and immunological techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351422"}
{"pmid": "4351425", "title": "Human growth hormone: a comparison of the results of plasma and serum assays using double-antibody techniques.", "content": "Human growth hormone: a comparison of the results of plasma and serum assays using double-antibody techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351425"}
{"pmid": "4351416", "title": "Studies on differentiation of avian pox viruses.", "content": "Studies on differentiation of avian pox viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351416"}
{"pmid": "4351418", "title": "Adenovirus infection and disease. II. Histopathology of natural and experimental disease.", "content": "Adenovirus infection and disease. II. Histopathology of natural and experimental disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351418"}
{"pmid": "4351417", "title": "Adenovirus infection and disease. I. Some characteristics of an isolate from chickens in Indiana.", "content": "Adenovirus infection and disease. I. Some characteristics of an isolate from chickens in Indiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351417"}
{"pmid": "4351426", "title": "A procedure for the determination of a renin inhibitor in human plasma.", "content": "A procedure for the determination of a renin inhibitor in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351426"}
{"pmid": "4351427", "title": "Effect of ampicillin on the urinary output of steroidal hormones in pregnant and non-pregnant women.", "content": "Effect of ampicillin on the urinary output of steroidal hormones in pregnant and non-pregnant women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351427"}
{"pmid": "4351419", "title": "Characterization of two reoviruses isolated from turkeys with infectious enteritis.", "content": "Characterization of two reoviruses isolated from turkeys with infectious enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351419"}
{"pmid": "4351428", "title": "Purine metabolism in primitive erythrocytes.", "content": "Purine metabolism in primitive erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351428"}
{"pmid": "4351430", "title": "Biochemical studies in the vole, Microtus montanus. II. The effects of a Trypanosoma brucei gambiense infection on the diurnal variation of hepatic glucose-6-phosphatase and liver glycogen.", "content": "Biochemical studies in the vole, Microtus montanus. II. The effects of a Trypanosoma brucei gambiense infection on the diurnal variation of hepatic glucose-6-phosphatase and liver glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351430"}
{"pmid": "4351429", "title": "Biochemical studies in the vole, Microtus montanus. I. The daily variation of hepatic glucose-6-phosphatase and liver glycogen.", "content": "Biochemical studies in the vole, Microtus montanus. I. The daily variation of hepatic glucose-6-phosphatase and liver glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351429"}
{"pmid": "4351431", "title": "Hydrolytic enzymes of the hepatopancreas of the ascidian, Pyura stolonifera.", "content": "Hydrolytic enzymes of the hepatopancreas of the ascidian, Pyura stolonifera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351431"}
{"pmid": "4351421", "title": "Isolation and characterization of viruses associated with transmissible enteritis (bluecomb) of turkeys.", "content": "Isolation and characterization of viruses associated with transmissible enteritis (bluecomb) of turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351421"}
{"pmid": "4351420", "title": "Isolation and characterization of a virus associated with arthritis of chickens.", "content": "Isolation and characterization of a virus associated with arthritis of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351420"}
{"pmid": "4351432", "title": "Wax ester biosynthesis by isolated membrane fractions from calanoid copepods.", "content": "Wax ester biosynthesis by isolated membrane fractions from calanoid copepods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351432"}
{"pmid": "4351433", "title": "Enzymes in facultative anaerobiosis of molluscs. I. Malic enzyme of oyster adductor muscle.", "content": "Enzymes in facultative anaerobiosis of molluscs. I. Malic enzyme of oyster adductor muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351433"}
{"pmid": "4351436", "title": "Arginyl-transfer ribonucleic-acid synthetase from Bacillus stearothermophilus. Purification, properties and mechanism of action.", "content": "Arginyl-transfer ribonucleic-acid synthetase from Bacillus stearothermophilus. Purification, properties and mechanism of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351436"}
{"pmid": "4351438", "title": "Structure of the parasporal inclusion of Bacillus thuringiensis Berliner: characterization of a repetitive subunit.", "content": "Structure of the parasporal inclusion of Bacillus thuringiensis Berliner: characterization of a repetitive subunit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351438"}
{"pmid": "4351439", "title": "Studies on the interaction of ligands with phosphorylase b using a spin-label probe.", "content": "Studies on the interaction of ligands with phosphorylase b using a spin-label probe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351439"}
{"pmid": "4351437", "title": "Energy-dependent changes in membranes of Rhodospirillum rubrum chromatophores as measured by 8-anilino-naphthalene-1-sulfonic acid.", "content": "Energy-dependent changes in membranes of Rhodospirillum rubrum chromatophores as measured by 8-anilino-naphthalene-1-sulfonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351437"}
{"pmid": "4351440", "title": "The subunit structure of the pyruvate-dehydrogenase complex from Escherichia coli K-12. The core complex.", "content": "The subunit structure of the pyruvate-dehydrogenase complex from Escherichia coli K-12. The core complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351440"}
{"pmid": "4351441", "title": "Benzene metabolism of Moraxella species.", "content": "Benzene metabolism of Moraxella species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351441"}
{"pmid": "4351443", "title": "Effect of strychnine on the primary evoked response and on the corticofugal reflex discharge.", "content": "Effect of strychnine on the primary evoked response and on the corticofugal reflex discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351443"}
{"pmid": "4351442", "title": "Characterization of the native and denatured conformations of tRNA Ser and tRNA Phe from yeast.", "content": "Characterization of the native and denatured conformations of tRNA Ser and tRNA Phe from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351442"}
{"pmid": "4351444", "title": "Reflexes involving triceps surae from the ankle joint of the cat.", "content": "Reflexes involving triceps surae from the ankle joint of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351444"}
{"pmid": "4351445", "title": "Peripheral neuropathies in diseases of internal organs.", "content": "Peripheral neuropathies in diseases of internal organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351445"}
{"pmid": "4351447", "title": "The development of the chick tertiary bronchus. II. The origin of the surface lining system.", "content": "The development of the chick tertiary bronchus. II. The origin of the surface lining system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351447"}
{"pmid": "4351446", "title": "The development of the chick tertiary bronchus. I. General development and the mode of production of the osmiophilic inclusion body.", "content": "The development of the chick tertiary bronchus. I. General development and the mode of production of the osmiophilic inclusion body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351446"}
{"pmid": "4351449", "title": "Corneal immune response to Herpes simplex virus antigens.", "content": "Corneal immune response to Herpes simplex virus antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351449"}
{"pmid": "4351448", "title": "Increased metabolic clearance of cortisol by stress-susceptible swine.", "content": "Increased metabolic clearance of cortisol by stress-susceptible swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351448"}
{"pmid": "4351450", "title": "Prevention of MIF activity by agents known to increase cellular cyclic AMP.", "content": "Prevention of MIF activity by agents known to increase cellular cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351450"}
{"pmid": "4351451", "title": "The effects of tetanus toxin on the motor end-plates of the mouse. An electron microscopic study.", "content": "The effects of tetanus toxin on the motor end-plates of the mouse. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351451"}
{"pmid": "4351453", "title": "Follow-up after hydatidiform mole: studies using radioimmunoassay for urinary human chorionic gonadotrophin (HCG).", "content": "Follow-up after hydatidiform mole: studies using radioimmunoassay for urinary human chorionic gonadotrophin (HCG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351453"}
{"pmid": "4351454", "title": "Fusion of erythrocytes by Sendai virus studied by immuno-freeze-etching.", "content": "Fusion of erythrocytes by Sendai virus studied by immuno-freeze-etching. Extensive fusion of human erythrocytes agglutinated by Sendai virus was observed after 30 s of incubation at 37 C. Electron microscopy of thin sections failed to reveal the presence of virions, viral fragments, or discrete viral antigens reactive with ferritin-labeled antibody at the sites of fusion. Immuno-freezeetching of membrane surfaces demonstrated the dispersal of viral envelope antigens from what appeared to be original sites of viral attachment. Virus-induced clustering of membrane glycoproteins was interpreted as resulting from interaction of viral antigens with membrane receptor proteins and forming the structural basis for fusion of membranes with one another.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351454"}
{"pmid": "4351456", "title": "Virus-induced proteins in pseudorabies-infected cells. I. Acid-extractable proteins of the nucleus.", "content": "Virus-induced proteins in pseudorabies-infected cells. I. Acid-extractable proteins of the nucleus. Three basic proteins have been identified in chromatin preparations from pseudorabies virus-infected cells. They appear to be virus specified and are similar in size and charge to host histones; one difference however is that they contain tryptophan. All are produced by 3 h postinfection, and two (IP II and III) seem to be arginine rich. Three similar proteins are also found in herpes simplex MP 17-infected cells, and two of these co-electrophorese with two of the pseudorabies proteins. Partially purified preparations of pseudorabies virus contain low amounts of all three proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351456"}
{"pmid": "4351455", "title": "Lack of sequence homology between the 70S RNA of various RNA tumor viruses and the DNA of simian virus 40 or polyoma virus.", "content": "Lack of sequence homology between the 70S RNA of various RNA tumor viruses and the DNA of simian virus 40 or polyoma virus. No significant hybridization was detected of DNA from simian virus 40 or polyoma virus, and of 70S RNA from avian myeloblastosis virus, murine leukemia virus (Rauscher), murine sarcoma virus (Kirsten), RD-114B, simian sarcoma virus-1, or Mason-Pfizer virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351455"}
{"pmid": "4351457", "title": "Polioviruses, coxsackieviruses, and echoviruses comparison of the genomes by RNA hybridization.", "content": "Polioviruses, coxsackieviruses, and echoviruses comparison of the genomes by RNA hybridization. Hybridization of single-stranded RNA from virions of human enteroviruses with denatured double-stranded RNA from infected cells indicates that a minimum of about 5% of the genome is shared by these viruses. Polynucleotide sequence relationships, furthermore, are consistent with the biologic classification into polioviruses, coxsackieviruses groups A and B, and echoviruses. In general, about 30 to 50% of the nucleotide sequences are shared by different serotypes of virus within each of these major groups, whereas among different groups less than 20% homology is observed. Coxsackievirus B4 appears to be more closely related to echoviruses than to group A coxsackieviruses, whereas polioviruses are only distantly related to any of the other agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351457"}
{"pmid": "4351458", "title": "RNA synthesis in cells infected with herpes simplex virus. VII. Control of transcription and of transcript abundancies of unique and common sequences of herpes simplex virus 1 and 2.", "content": "RNA synthesis in cells infected with herpes simplex virus. VII. Control of transcription and of transcript abundancies of unique and common sequences of herpes simplex virus 1 and 2. Analysis of the kinetics of hybridization in liquid of labeled herpes simplex virus (HSV) 1 and 2 DNAs with excess unlabeled RNA extracted at 2 (early) and 8 (late) h postinfection revealed the following. (i) The RNA transcripts present in the HSV-1-infected cells at 2 and 8 h postinfection are complementary to 44 and 48% of HSV-1 DNA. The RNA transcripts present in the HSV-2-infected cells at 2 and 8 h postinfection are complementary to 21 and 50% of HSV-2 DNA. (ii) The transcripts present in 2-h HSV-1- or HSV-2-infected cells treated with cycloheximide are complementary to 44 and 45% of the respective DNAs. (iii) The RNA transcripts present in the HSV-1-infected cells at 2 h postinfection and in HSV-2-infected cells at 8 h postinfection form 2 classes, abundant and scarce, differing in molar concentrations. The RNA transcripts present in the HSV-2-infected cells at 2 h postinfection form only one abundance class. (iv) The transcripts present in the HSV-1-infected cells at 8 h postinfection are complementary to 24% of HSV-2 DNA and therefore 50% of the transcribed HSV-1 sequences are shared by the two viruses. Of the RNA sequences complementary to HSV-2 DNA, 13% arise from HSV-1 templates specifying abundant RNA and 11% arise from HSV-1 templates specifying scarce RNA. Thus, the DNA sequences shared in common by HSV-1 and HSV-2 DNAs constitute 71% of the HSV-1 templates specifying abundant RNA and 39% of sequences specifying scarce RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351458"}
{"pmid": "4351459", "title": "Radioimmunoassay for avian C-type virus group-specific antigen: detection in normal and virus-transformed cells.", "content": "Radioimmunoassay for avian C-type virus group-specific antigen: detection in normal and virus-transformed cells. A radioimmunoassay has been developed for detection of avian C-type virus (30,000 mol wt) group-specific (gs) antigen. The method is 10- to 1,000-fold more sensitive than immunological methods previously available. By the radioimmunoassay technique, normal chicken embryo cells, which have previously been classified as gs negative or weakly gs positive, contain clearly detectable amounts of gs antigen. The assay has been used to study the effect of chemical induction and superinfection by mammalian C-type viruses on the expression of avian gs antigen in mammalian cells nonproductively transformed by avian sarcoma viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351459"}
{"pmid": "4351460", "title": "Complementary RNA species isolated from vesicular stomatitis (HR strain) defective virions.", "content": "Complementary RNA species isolated from vesicular stomatitis (HR strain) defective virions. The wild-type strain of vesicular stomatitis virus (VSV) contains in its complete virion (VSV-1, B particles) a minus strand RNA. The principle defective particle of the wild-type strain (VSV-111, T particles) contains a shorter minus strand, homologous to part of the VSV-1 genome. Neither virion contains any detectable complementary (plus) strand RNA. In contrast, a preparation of a heat-resistant (HR) strain of VSV containing defective virions was found to contain both plus (21%) and minus strand RNA, present in several distinct size classes. It was found that the RNA in the HR virion preparation was at least 94% single-stranded and principally (96%) in ribonucleoprotein complexes. On extraction the plus and minus strand RNA species partially annealed to give a population of double- and multistranded RNA species. A small amount of RNA polymerase activity was associated with the HR defective virus preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351460"}
{"pmid": "4351462", "title": "Electrophoretic differences in the capsid proteins of simian virus 40 plaque mutants.", "content": "Electrophoretic differences in the capsid proteins of simian virus 40 plaque mutants. The structural proteins of three mutants of simian virus 40 (SV40) which differ in plaque size, temperature sensitivity, oncogenicity, host cell restriction, and immunological properties were studied. The polypeptide components of these SV40 strains could not be distinguished by their polyacrylamide gel electrophoretic patterns. When the dissociated virions of two of the mutants were analyzed by the isoelectric focusing technique in a urea gradient, the capsid protein peaks were found to differ significantly in their isoelectric points. The capsid protein of the small-plaque mutant had an isoelectric point of pH 6.51 as compared with pH 6.28 for the large-plaque strain. Isoelectric focusing of the isolated capsid protein revealed three components, a single major subunit and two minor forms. The coat proteins of two of the mutants, small-plaque and minute-plaque strains, were indistinguishable by this technique. The capsid protein peaks obtained by isoelectric focusing were further analyzed by polyacryalmide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351462"}
{"pmid": "4351463", "title": "Cytomegalovirus replication in cells pretreated with 5-iodo-2'-deoxyuridine.", "content": "Cytomegalovirus replication in cells pretreated with 5-iodo-2'-deoxyuridine. The replication of human cytomegalovirus (CMV) in cells pretreated with 5-iodo-2'-deoxyuridine (IUdR) was studied. Pretreatment of cells with IUdR enhanced several parameters of virus replication. Virus grown in drug-treated cells exhibited a shorter eclipse period and the cells produced more infectious virus sooner than did untreated cells. There was an approximate fivefold increase in virus yield per cell in the drug-treated samples when compared to control cultures. The time required for plaque development was shortened by 6 days in drug-treated cultures. Pretreatment of cells with IUdR also increased plaquing efficiency of the virus by approximately 10-fold. The enhancement of virus replication by IUdR was further demonstrated by varying the multiplicity of infection. In a 7-day period there was a 100-fold increase in sensitivity of the cultures for virus detection when the cells had been previously exposed to IUdR. The data presented indicate the possibility that IUdR interferes with the production of a cellular product inhibitory for CMV replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351463"}
{"pmid": "4351461", "title": "Suppression of amber mutations of bacteriophage T4 gene 43 (DNA polymerase) by translational ambiguity.", "content": "Suppression of amber mutations of bacteriophage T4 gene 43 (DNA polymerase) by translational ambiguity. The growth properties of twelve different amber (am) mutants of bacteriophage T4 gene 43 (DNA polymerase) were examined by using nonpermissive (su(-)) as well as permissive (su(+)) Escherichia coli hosts. It was found that most of these mutants were measurably suppressed in su(-) hosts by translational ambiguity (misreading of codons during protein synthesis). The ability of these mutants to grow in response to this form of weak suppression probably means that the T4 gene 43 DNA polymerase can be effective in supporting productive DNA replication when it is supplied in small amounts. By similar criteria, studies with other phage mutants suggested that the products of T4 genes 62 (uncharacterized), 44 (uncharacterized), 42 (dCMP-hydroxymethylase), and 56 (dCTPase) are also effective in small amounts. Some T4 gene products, such as the product of gene 41 (uncharacterized), seem to be partially dispensable for phage growth since am mutants of such genes do propagate, although weakly, in streptomycin-resistant su(-) hosts which appear to have lost the capacity to suppress am mutations by ambiguity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351461"}
{"pmid": "4351465", "title": "Nonproductive infection of guinea pig cells with human cytomegalovirus.", "content": "Nonproductive infection of guinea pig cells with human cytomegalovirus. Human cytomegalovirus was capable of adsorbing to and penetrating guinea pig cells, but was unable to replicate new virus. Cultures infected with virus inoculum of high titer showed a cytopathic effect (CPE) characterized by cell rounding. This CPE depended upon the presence of infectious virus, and its extent was directly related to the multiplicity of infection. Staining by indirect immunofluorescence by using human convalescent sera was positive as early as 4 h postinfection. Maximal fluorescence was observed 24 h postinfection when 50% of the cells contained fluorescent antigens both in nuclei and cytoplasm. No evidence for viral replication was found, and no defective particles were detected by electron microscopy. Treatment with actinomycin D or with cycloheximide strongly inhibited both the fluorescent antigens and the CPE, whereas 5-fluorodeoxyuridine and bromodeoxyuridine were ineffective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351465"}
{"pmid": "4351464", "title": "Growth characteristics of cytomegalovirus in human fibroblasts with demonstration of protein synthesis early in viral replication.", "content": "Growth characteristics of cytomegalovirus in human fibroblasts with demonstration of protein synthesis early in viral replication. In high-multiplicity infection of human fibroblasts, human cytomegalovirus of WI-38 human diploid cells produced early cell rounding 6 to 24 h after inoculation. This early cell rounding was caused only by inoculation with infectious virions. Inhibitors of protein synthesis, but not DNA inhibitors, prevented this cytopathic effect. Apparently, a new protein is synthesized in infected fibroblasts from about 2 h postinoculation. Infectivity of cell-associated and supernatant infectious virus reached maximal levels at 5 to 7 and 10 days postinoculation, respectively. Synthesis of DNA, infectious virus, complement-fixing antigen, and precipitin antigen all began between 24 and 48 h, with the bulk of synthesis occurring 48 to 96 h postinoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351464"}
{"pmid": "4351466", "title": "Intrauterine infection with herpes simplex virus. Resultant congenital malformations.", "content": "Intrauterine infection with herpes simplex virus. Resultant congenital malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351466"}
{"pmid": "4351467", "title": "Benign intrathoracic lesions mimicking recurrent cancer.", "content": "Benign intrathoracic lesions mimicking recurrent cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351467"}
{"pmid": "4351469", "title": "Methodology and management of simian toxicology studies with emphasis on special technics.", "content": "Methodology and management of simian toxicology studies with emphasis on special technics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351469"}
{"pmid": "4351468", "title": "Hematologic and serum electrolyte values of the C57BL-6J male mouse in maturity and senescence.", "content": "Hematologic and serum electrolyte values of the C57BL-6J male mouse in maturity and senescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351468"}
{"pmid": "4351470", "title": "Breeding the African green monkey, Cercopithecus aethiops, in a laboratory environment.", "content": "Breeding the African green monkey, Cercopithecus aethiops, in a laboratory environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351470"}
{"pmid": "4351471", "title": "Pathogenic properties of Molineus torulosus in capuchin monkeys, Cebus apella.", "content": "Pathogenic properties of Molineus torulosus in capuchin monkeys, Cebus apella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351471"}
{"pmid": "4351472", "title": "Cataract development in streptozotocin-diabetic monkeys (Macaca nemestrina).", "content": "Cataract development in streptozotocin-diabetic monkeys (Macaca nemestrina).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351472"}
{"pmid": "4351474", "title": "Comparison of old tuberculin and purified protein derivative in Macaca mulatta.", "content": "Comparison of old tuberculin and purified protein derivative in Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351474"}
{"pmid": "4351473", "title": "Response of mice to Corynebacterium kutscheri on footpad injection.", "content": "Response of mice to Corynebacterium kutscheri on footpad injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351473"}
{"pmid": "4351475", "title": "Some observations on the circadian rhythm of Choloepus hoffmanni, the two-toed sloth.", "content": "Some observations on the circadian rhythm of Choloepus hoffmanni, the two-toed sloth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351475"}
{"pmid": "4351476", "title": "Amino acid levels in the plasma of fasting macaques (Macaca cyclopis, M. fascicularis, and M. mulatta).", "content": "Amino acid levels in the plasma of fasting macaques (Macaca cyclopis, M. fascicularis, and M. mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351476"}
{"pmid": "4351478", "title": "Production of hyperimmune serum with mature rabbits.", "content": "Production of hyperimmune serum with mature rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351478"}
{"pmid": "4351477", "title": "Isolation and in vitro characterization of a herpesvirus from field mouse (Microtus pennsylvanicus).", "content": "Isolation and in vitro characterization of a herpesvirus from field mouse (Microtus pennsylvanicus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351477"}
{"pmid": "4351479", "title": "Effect of anesthetic agents on exercised, atropinized rats.", "content": "Effect of anesthetic agents on exercised, atropinized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351479"}
{"pmid": "4351480", "title": "Fibrosarcoma associated with Cysticercus fasciolaris.", "content": "Fibrosarcoma associated with Cysticercus fasciolaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351480"}
{"pmid": "4351481", "title": "Some characteristics of strain SJL-JDg mice.", "content": "Some characteristics of strain SJL-JDg mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351481"}
{"pmid": "4351482", "title": "Differential diagnosis of an obscure bone disease in an infant rhesus monkey.", "content": "Differential diagnosis of an obscure bone disease in an infant rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351482"}
{"pmid": "4351483", "title": "A method for preventing oral ingestion of topically applied materials.", "content": "A method for preventing oral ingestion of topically applied materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351483"}
{"pmid": "4351484", "title": "Meckel's diverticulum in a rat.", "content": "Meckel's diverticulum in a rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351484"}
{"pmid": "4351485", "title": "A mouse bleeding technic yielding consistent volume with minimal hemolysis.", "content": "A mouse bleeding technic yielding consistent volume with minimal hemolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351485"}
{"pmid": "4351486", "title": "Basal-cell tumor in a Virginia opossum (Didelphis marsupialis).", "content": "Basal-cell tumor in a Virginia opossum (Didelphis marsupialis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351486"}
{"pmid": "4351487", "title": "Spontaneous lesions seen at necropsy in 7 owl monkeys (Aotus trivirgatus).", "content": "Spontaneous lesions seen at necropsy in 7 owl monkeys (Aotus trivirgatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351487"}
{"pmid": "4351495", "title": "Nonsegregated acute psychiatric admissions to general hospitals--continuity of care within the community hospital.", "content": "Nonsegregated acute psychiatric admissions to general hospitals--continuity of care within the community hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351495"}
{"pmid": "4351496", "title": "Proteins of human cortical neurons during development.", "content": "Proteins of human cortical neurons during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351496"}
{"pmid": "4351500", "title": "Concentrations of human chorionic gonadotropin, progesterone, and unconjugated and total estriol in umbilical artery and vein plasma at term.", "content": "Concentrations of human chorionic gonadotropin, progesterone, and unconjugated and total estriol in umbilical artery and vein plasma at term.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351500"}
{"pmid": "4351490", "title": "The assay of ACTH in plasma.", "content": "The assay of ACTH in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351490"}
{"pmid": "4351502", "title": "Fibrous histiocytoma of the paranasal sinuses. Report of a case.", "content": "Fibrous histiocytoma of the paranasal sinuses. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351502"}
{"pmid": "4351503", "title": "Synovial sarcoma of the head and neck.", "content": "Synovial sarcoma of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351503"}
{"pmid": "4351501", "title": "The influence of oral contraceptive steroids on serum lipids.", "content": "The influence of oral contraceptive steroids on serum lipids. The effects of oral contraceptives on serum lipids were investigated in humans and monkeys at the Temple University Health Sciences Center.  The compositions of the pills were: 1) 2.0 mg chlormadinone acetate, .08 mg mestranol; 2) 10.0 mg medroxyprogesterone acetate, .05 mg ethinyl estradiol; 3) 1.0 mg ethynodiol diacetate, .1 mg mestranol; 4) 1.0 mg norethindrone acetate, .05 mg  ethinyl estradiol, and 5) .5 mg norgestrel, .05 mg ethinyl estradiol.  238 immediately puerperal black women, healthy and aged 20-30, were divided into 6 groups for study purposes; each of 5 groups used a separate oral therapy, while the sixth group (control) was fitted with a plastic intrauterine device.  75 women were still participating in the study at 54 weeks.  All of the drugs significantly increased the concentrations of serum cholesterol, serum triglycerides, total phospholipids, and fatty acids.  The influence of the drugs on lipoproteins was variable.  The higher its progestogen/estrogen ratio, the greater influence a drug had on lipid concentrations.  Some of the same effects were seen in 14 mature female squirrel monkeys (Cebus albifrons), which were studied in a similar manner for about 30 cycles; however, only drugs 1, 2, and 3 were used in this part of the study.  Clinical observations of the patients in this study, showed no relationship between serum phosphatides participating in the coagulation mechanism and the production of thromboembolic phenomena.  The researchers found no justification for the delay of oral contraceptive prescription after childbirth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351501"}
{"pmid": "4351488", "title": "Solomon A. Berson and Rosalyn S. Yalow: a scientific appreciation.", "content": "Solomon A. Berson and Rosalyn S. Yalow: a scientific appreciation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351488"}
{"pmid": "4351494", "title": "Possible clues in the continuing search for the subcellular basis of thyroid hormone action.", "content": "Possible clues in the continuing search for the subcellular basis of thyroid hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351494"}
{"pmid": "4351504", "title": "Bilateral glomus tumors of the temporal bone. Report of a case.", "content": "Bilateral glomus tumors of the temporal bone. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351504"}
{"pmid": "4351489", "title": "Radioimmunoassay of human plasma ACTH and the pathogenesis of Cushing's disease.", "content": "Radioimmunoassay of human plasma ACTH and the pathogenesis of Cushing's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351489"}
{"pmid": "4351505", "title": "Lipid composition of selected strains of Yersinia pestis and Yersinia pseudotuberculosis.", "content": "Lipid composition of selected strains of Yersinia pestis and Yersinia pseudotuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351505"}
{"pmid": "4351492", "title": "Berson and Yalow's radioimmunoassay for parathyroid hormone (PTH): a clinical progress report.", "content": "Berson and Yalow's radioimmunoassay for parathyroid hormone (PTH): a clinical progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351492"}
{"pmid": "4351491", "title": "Observations on the control and release of growth hormone in plasma.", "content": "Observations on the control and release of growth hormone in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351491"}
{"pmid": "4351506", "title": "The enzymic synthesis of disialoganglioside: rat brain cytidine-5'-monophospho-N-acetylneuraminic acid: monosialoganglioside (G M1 ) sialyltransferase.", "content": "The enzymic synthesis of disialoganglioside: rat brain cytidine-5'-monophospho-N-acetylneuraminic acid: monosialoganglioside (G M1 ) sialyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351506"}
{"pmid": "4351493", "title": "Secondary hyperparathyroidism.", "content": "Secondary hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351493"}
{"pmid": "4351509", "title": "The stimulation of bovine epididymal sperm metabolism by cyclic nucleotide phosphodiesterase inhibitors.", "content": "The stimulation of bovine epididymal sperm metabolism by cyclic nucleotide phosphodiesterase inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351509"}
{"pmid": "4351508", "title": "Gonadotropin receptor of a mouse luteoma: interactions with luteinizing hormone (LH) and its   and   subunits.", "content": "Gonadotropin receptor of a mouse luteoma: interactions with luteinizing hormone (LH) and its   and   subunits. A radioligand-receptor system for luteinizing hormone (LH), USING transplantable mouse luteoma, was used to investigate the interactions of LH, other peptide hormones, and LH subunits.  Since tumor size decreased as did production of androgenic hormones following hypophysectomy, the luteoma is believed to have been dependent on pituitary tropic hormones; posthypophysectomy histologic changes supported this conclusion.  An homogenate was prepared from 1-4 gm luteomas, which had been borne by mice for 4-10 months.  Ovine LH, bovine LH, and human chorionic gonadotrophin reduced the binding of iodine-125 human luteinizing hormone (125-I-hLH).  Growth hormone, adrenocorticotrophic hormone, and prolactin had no capacity to interfere with binding of 125-I-hLH.  Though follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH) reduced the binding somewhat, the reductions were consistent with the known presence of contaminating amounts of LH in the FSH and TSH.  The accumulated results of a number of experiments suggest that binding to the luteoma LH receptor requires a particular polypeptide structural conformation, one found in the native hormone but found in neither alpha nor beta subunit alone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351508"}
{"pmid": "4351507", "title": "Lipids in tissues of the eye. 8. Sphingomyelinase of the lens.", "content": "Lipids in tissues of the eye. 8. Sphingomyelinase of the lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351507"}
{"pmid": "4351510", "title": "The effects of cyclic nucleotide phosphodiesterase inhibitors on ejaculated porcine spermatozoan metabolism.", "content": "The effects of cyclic nucleotide phosphodiesterase inhibitors on ejaculated porcine spermatozoan metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351510"}
{"pmid": "4351511", "title": "Cell-mediated immunity and antibodies to Herpesvirus hominis type 1 in oral leukoplakia and carcinoma.", "content": "Cell-mediated immunity and antibodies to Herpesvirus hominis type 1 in oral leukoplakia and carcinoma. Cell-mediated and humoral immune responses to Herpesvirus hominis type 1 (HVH1) and Candida albicans were studied in patients with leukoplakia, showing a histological spectrum of changes from epithelial keratosis to acanthosis and atypia, and in patients with carcinoma. The results were ranked according to increasing values of stimulation indices of lymphocyte transformation to HVH1, and the corresponding macrophage migration inhibition indices, and complement fixing antibody titres of each patient were correlated. This revealed that most patients with epithelial atypia were clustered to that end of the spectrum which had the highest stimulation and migration indices to HVH1; this relationship was not evident with C. albicans. In patients with keratosis and acanthosis there was a significant lack of correlation between lymphocyte transformation and migration inhibition to both HVH1 and C. albicans. In carcinoma the indices of lymphocyte transformation and migration inhibition to HVH1 and C. albicans were depressed. Furthermore, a significant negative correlation was found between lymphocyte transformation and migration inhibition to HVH1, unlike the positive correlation in control subjects. Complement fixing antibodies to HVH1, HVH2, cytomegalovirus and adenovirus, and fluorescent antibodies to C. albicans failed to show a significant change in titre in any one group of subjects tested. The results suggest a cell-mediated immune defect in leukoplakia, with a dissociation between lymphocyte transformation and macrophage migration inhibition to HVH1 and C. albicans in cases of keratosis or acanthosis. A specific increase in cell-mediated immunity to HVH1 in leukoplakia with epithelial atypia and the sequential changes argue in favour of a possible participation of HVH1 in carcinomatous transformation of some leukoplakias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351511"}
{"pmid": "4351513", "title": "Tomography of the cavernous sinuses.", "content": "Tomography of the cavernous sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351513"}
{"pmid": "4351497", "title": "The effects of arterial blood pressure on the regional cerebral blood volume by X-ray fluorescence.", "content": "The effects of arterial blood pressure on the regional cerebral blood volume by X-ray fluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351497"}
{"pmid": "4351512", "title": "Excretion of alpha-foetoprotein in the urine of pregnant rats and hepatoma-bearing animals.", "content": "Excretion of alpha-foetoprotein in the urine of pregnant rats and hepatoma-bearing animals. Urine of normal rats, pregnant animals and animals bearing chemically induced hepatoma was tested with antisera to foetoproteins by the double immunodiffusion technique. Antigens were not detected in the urine of normal rats. Alpha-foetoprotein was demonstrated in the urine of pregnant rats and hepatomabearing animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351512"}
{"pmid": "4351516", "title": "Thalamic regulation of synaptic transmission in the ventrolateral nucleus during natural sleep and waking.", "content": "Thalamic regulation of synaptic transmission in the ventrolateral nucleus during natural sleep and waking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351516"}
{"pmid": "4351517", "title": "Two negative dorsal root potentials evoke a positive dorsal root potential.", "content": "Two negative dorsal root potentials evoke a positive dorsal root potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351517"}
{"pmid": "4351515", "title": "The neural pathways relaying reflex inhibition from semicircular canals to extraocular muscles of rabbits.", "content": "The neural pathways relaying reflex inhibition from semicircular canals to extraocular muscles of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351515"}
{"pmid": "4351518", "title": "Influence of the locus coeruleus on transmission in the spinal trigeminal nucleus neurons.", "content": "Influence of the locus coeruleus on transmission in the spinal trigeminal nucleus neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351518"}
{"pmid": "4351520", "title": "Acetylcholine and slow synaptic inhibition in frog sympathetic ganglion cells.", "content": "Acetylcholine and slow synaptic inhibition in frog sympathetic ganglion cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351520"}
{"pmid": "4351519", "title": "Slow synaptic inhibition: evidence for synaptic inactivation of sodium conductance in sympathetic ganglion cells.", "content": "Slow synaptic inhibition: evidence for synaptic inactivation of sodium conductance in sympathetic ganglion cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351519"}
{"pmid": "4351521", "title": "Angiotensin as a possible intrarenal hormone in isolated dog kidneys.", "content": "Angiotensin as a possible intrarenal hormone in isolated dog kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351521"}
{"pmid": "4351522", "title": "Metastatic ovarian cancer.", "content": "Metastatic ovarian cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351522"}
{"pmid": "4351524", "title": "Purification of a messenger-specific initiation factor from ascites-cell supernatant.", "content": "Purification of a messenger-specific initiation factor from ascites-cell supernatant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351524"}
{"pmid": "4351525", "title": "Reduced Bohr effect in NO-ligated chironomus haemoglobin.", "content": "Reduced Bohr effect in NO-ligated chironomus haemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351525"}
{"pmid": "4351526", "title": "Interactions of substrates with a purified 4-methoxybenzoate monooxygenase system (O-demethylating) from Pseudomonas putida.", "content": "Interactions of substrates with a purified 4-methoxybenzoate monooxygenase system (O-demethylating) from Pseudomonas putida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351526"}
{"pmid": "4351527", "title": "Structure of protocollagen proline hydroxylase from chick embryos.", "content": "Structure of protocollagen proline hydroxylase from chick embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351527"}
{"pmid": "4351528", "title": "Biosynthesis of cartilage procollagen.", "content": "Biosynthesis of cartilage procollagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351528"}
{"pmid": "4351529", "title": "IUPAC-IUB commission on biochemical nomenclature (CBN). Nomenclature of iron-sulfur proteins. 1973 recommendations.", "content": "IUPAC-IUB commission on biochemical nomenclature (CBN). Nomenclature of iron-sulfur proteins. 1973 recommendations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351529"}
{"pmid": "4351530", "title": "Electron-transport chains of Escherichia coli. Reconstitution of respiration in a 5-aminolaevulinic acid-requiring mutant.", "content": "Electron-transport chains of Escherichia coli. Reconstitution of respiration in a 5-aminolaevulinic acid-requiring mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351530"}
{"pmid": "4351532", "title": "86 Rb transport, water and cation concentrations in lenses exposed to polymyxin B sulfate.", "content": "86 Rb transport, water and cation concentrations in lenses exposed to polymyxin B sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351532"}
{"pmid": "4351531", "title": "Kinetics of the interaction between pig-plasma benzylamine oxidase and substrate.", "content": "Kinetics of the interaction between pig-plasma benzylamine oxidase and substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351531"}
{"pmid": "4351534", "title": "EMS-induced mitotic recombination in a diploid, heterozygous for two complementing ade2 alleles of Saccharomyces cerevisiae.", "content": "EMS-induced mitotic recombination in a diploid, heterozygous for two complementing ade2 alleles of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351534"}
{"pmid": "4351535", "title": "Isozymes of experimentally induced primary sarcomas in the rat.", "content": "Isozymes of experimentally induced primary sarcomas in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351535"}
{"pmid": "4351536", "title": "Lymphocyte and antibody cytotoxicity to tumor cells measured by a micro- 51 chromium release assay.", "content": "Lymphocyte and antibody cytotoxicity to tumor cells measured by a micro- 51 chromium release assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351536"}
{"pmid": "4351537", "title": "Periodate induced lymphocyte transformation. I. Inhibition by sulfhydryl reducing agents and sugars.", "content": "Periodate induced lymphocyte transformation. I. Inhibition by sulfhydryl reducing agents and sugars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351537"}
{"pmid": "4351538", "title": "Induction of systemic delayed hypersensitivity during experimental viral infection of the respiratory tract with a myxovirus or paramyxovirus.", "content": "Induction of systemic delayed hypersensitivity during experimental viral infection of the respiratory tract with a myxovirus or paramyxovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351538"}
{"pmid": "4351539", "title": "Effects of pyran copolymer on leukemogenesis in immunosuppressed AKR mice.", "content": "Effects of pyran copolymer on leukemogenesis in immunosuppressed AKR mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351539"}
{"pmid": "4351540", "title": "Tumors of minor salivary glands. A study of 23 cases.", "content": "Tumors of minor salivary glands. A study of 23 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351540"}
{"pmid": "4351542", "title": "Insulinoma in an eighty-year old.", "content": "Insulinoma in an eighty-year old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351542"}
{"pmid": "4351541", "title": "Gastrointestinal bleeding and hepatoma. Diagnostic value of celiac angiography.", "content": "Gastrointestinal bleeding and hepatoma. Diagnostic value of celiac angiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351541"}
{"pmid": "4351543", "title": "An attempt to evaluate the influence of neighboring amino acids (n-1) and (n+1) on the backbone conformation of amino acid (n) in proteins. Use in predicting the three-dimensional structure of the polypeptide backbone of other proteins.", "content": "An attempt to evaluate the influence of neighboring amino acids (n-1) and (n+1) on the backbone conformation of amino acid (n) in proteins. Use in predicting the three-dimensional structure of the polypeptide backbone of other proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351543"}
{"pmid": "4351544", "title": "Spreading depression, sustained potential shifts, and metabolic activity of cerebral cortex of cats.", "content": "Spreading depression, sustained potential shifts, and metabolic activity of cerebral cortex of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351544"}
{"pmid": "4351545", "title": "Bilateral nephroblastoma.", "content": "Bilateral nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351545"}
{"pmid": "4351546", "title": "Fibrous histiocytoma of the scrotum in an infant.", "content": "Fibrous histiocytoma of the scrotum in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351546"}
{"pmid": "4351548", "title": "Occurrence of (+)-erythro-2,3-dihydroxyhexacosanoic acid in cerebrin from the yeast Saccharomyces cerevisiae.", "content": "Occurrence of (+)-erythro-2,3-dihydroxyhexacosanoic acid in cerebrin from the yeast Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351548"}
{"pmid": "4351550", "title": "Diagnosis of mammary cancer.", "content": "Diagnosis of mammary cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351550"}
{"pmid": "4351549", "title": "Sarcomas of the breast.", "content": "Sarcomas of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351549"}
{"pmid": "4351551", "title": "Pathology of mammary carcinoma.", "content": "Pathology of mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351551"}
{"pmid": "4351553", "title": "Segregation kinetics of colicinogenic factor col E1 from a bacterial population temperature sensitive for DNA polymerase I.", "content": "Segregation kinetics of colicinogenic factor col E1 from a bacterial population temperature sensitive for DNA polymerase I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351553"}
{"pmid": "4351555", "title": "Kinetics of phosphorylation and dephosphorylation of testis histones and their possible role in determining chromosomal structure.", "content": "Kinetics of phosphorylation and dephosphorylation of testis histones and their possible role in determining chromosomal structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351555"}
{"pmid": "4351556", "title": "Stimulation of cAMP synthesis by glucose in a mutant of E. coli B-r.", "content": "Stimulation of cAMP synthesis by glucose in a mutant of E. coli B-r.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351556"}
{"pmid": "4351561", "title": "Psychiatric complications of everyday drugs.", "content": "Psychiatric complications of everyday drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351561"}
{"pmid": "4351562", "title": "Health hazards of silicious material.", "content": "Health hazards of silicious material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351562"}
{"pmid": "4351568", "title": "Metabolic alterations after chronic exposure to  -chlordane.", "content": "Metabolic alterations after chronic exposure to  -chlordane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351568"}
{"pmid": "4351571", "title": "Stereophotogrammetric techniques for measurements of the eye ground. An analysis of the correlation and variation of parameters measured from the optic cup and disc in 115 subjects.", "content": "Stereophotogrammetric techniques for measurements of the eye ground. An analysis of the correlation and variation of parameters measured from the optic cup and disc in 115 subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351571"}
{"pmid": "4351572", "title": "Hydrosmotic effect of angiotensin II: isolated toad skin.", "content": "Hydrosmotic effect of angiotensin II: isolated toad skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351572"}
{"pmid": "4351573", "title": "Increased cardiovascular reactivity after bilateral nephrectomy in the rat.", "content": "Increased cardiovascular reactivity after bilateral nephrectomy in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351573"}
{"pmid": "4351574", "title": "The action of trypan blue on intraparticulate hydrolysis in liver phagolysosomes and on a lysosomal enzyme. The linking of the dye to proteins.", "content": "The action of trypan blue on intraparticulate hydrolysis in liver phagolysosomes and on a lysosomal enzyme. The linking of the dye to proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351574"}
{"pmid": "4351575", "title": "Age factor and the pattern of change in craniofacial structures.", "content": "Age factor and the pattern of change in craniofacial structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351575"}
{"pmid": "4351576", "title": "Growth standards for the tibia and radius in children aged one month through eighteen years.", "content": "Growth standards for the tibia and radius in children aged one month through eighteen years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351576"}
{"pmid": "4351577", "title": "Norms of size and annual increments of six anatomical measures of the cranium in boys and girls from four to fifteen years of age.", "content": "Norms of size and annual increments of six anatomical measures of the cranium in boys and girls from four to fifteen years of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351577"}
{"pmid": "4351579", "title": "The dating of Lantian man and his significance for analyzing trends in human evolution.", "content": "The dating of Lantian man and his significance for analyzing trends in human evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351579"}
{"pmid": "4351578", "title": "Osteoporotic bone loss in two prehistoric Indian populations.", "content": "Osteoporotic bone loss in two prehistoric Indian populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351578"}
{"pmid": "4351581", "title": "Parathyroid hormone receptor in bovine kidney cortex plasma membranes.", "content": "Parathyroid hormone receptor in bovine kidney cortex plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351581"}
{"pmid": "4351582", "title": "A function of synovial membrane of normal and diseased humans in relation to the movement of small-molecular-weight ions.", "content": "A function of synovial membrane of normal and diseased humans in relation to the movement of small-molecular-weight ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351582"}
{"pmid": "4351580", "title": "Uptake of vitamin B 12  by phytohaemagglutinin-transformed lymphocytes.", "content": "Uptake of vitamin B 12  by phytohaemagglutinin-transformed lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351580"}
{"pmid": "4351584", "title": "Stimulation of H-3-leucine incorporation into the proinsulin and insulin fraction of isolated pancreatic mouse islets in the presence of glucagon, theophylline and cyclic AMP.", "content": "Stimulation of H-3-leucine incorporation into the proinsulin and insulin fraction of isolated pancreatic mouse islets in the presence of glucagon, theophylline and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351584"}
{"pmid": "4351583", "title": "Pancreatic islet transplantation in the rat.", "content": "Pancreatic islet transplantation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351583"}
{"pmid": "4351585", "title": "Cross relationships among 37 rhinoviruses demonstrated by virus neutralization with potent monotypic rabbit antisera.", "content": "Cross relationships among 37 rhinoviruses demonstrated by virus neutralization with potent monotypic rabbit antisera. Antisera produced in rabbits to 37 rhinovirus (RV) types have been examined for antibody to the 36 corresponding heterologous types. Reciprocal neutralization was noted between RV types 2 and 49 and RV types 13 and 41. Five additional monotypic rhinoviral rabbit antisera neutralized one heterologous rhinovirus. Neutralizing antibody titers against heterologous RV serotypes were similar to those shown in the RV 1A, 1B and RV 9, 32 reciprocal cross-reactions, and would not be expected to result in false identification of serotypes. Comparison of neutralizing antibody titers and neutralization rate constants in serial serum specimens of immunized rabbits showed that antibody response to the immunizing RV type and the cross-reacting type followed a similar time pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351585"}
{"pmid": "4351586", "title": "Guinea pig herpes-like virus infection. I. Antibody response and virus persistence in guinea pigs after experimental infection.", "content": "Guinea pig herpes-like virus infection. I. Antibody response and virus persistence in guinea pigs after experimental infection. Guinea pigs, experimentally infected with guinea pig herpes-like virus produced antibodies which were detectable by indirect hemagglutination (IHA), complement-fixation (CF), and neutralization tests. The IHA test appeared to be a more sensitive method than the CF or neutralization test for determining antibody response in guinea pigs immediately after infection, but the IHA method was not suitable for the detection of antibody in animals receiving small doses of virus. Antibody titers obtained by CF tests were generally higher than those obtained by the neutralization test, and they followed the same time course when individual animals were studied serially. Intracardiac inoculation produced the best antibody response in guinea pigs when compared with other routes of infection. Guinea pigs infected by the intraperitoneal, intranasal, or oral route showed rising antibody titers but the levels were low. Infectious virus was isolated from and persisted in all inoculated animals in the presence of antibody regardless of the route of inoculation. Recovery of infectious virus required cultivation or cocultivation of tissue cells containing virus. The administration of antilymphocyte sera delayed the appearance of IHA antibody but had no effect on antibodies determined by the CF- and neutralization tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351586"}
{"pmid": "4351588", "title": "Interaction of lymphoid and nonlymphoid cells with the lymphocytosis-promoting factor of Bordetella pertussis.", "content": "Interaction of lymphoid and nonlymphoid cells with the lymphocytosis-promoting factor of Bordetella pertussis. The activity of soluble lymphocytosis-promoting factor (LPF) from Bordetella pertussis decreased after brief in vitro incubation with lymphoid cells or erythrocytes. The LPF activity was found to be associated with the cells used, and injection of the cells produced a leukocytosis and lymphocytosis which completely accounted for the loss of soluble activity. Attachment of LPF to cells was found to be reversible in vitro. It is suggested that reversible binding occurs in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351588"}
{"pmid": "4351587", "title": "Guinea pig herpes-like virus infections. II. Antibody response and virus persistence in mice and rabbits.", "content": "Guinea pig herpes-like virus infections. II. Antibody response and virus persistence in mice and rabbits. Mice inoculated with guinea pig herpes-like virus produced minimal, if any, antibody response, and no virus was isolated from the inoculated animals 64 days after administration. The antibody response in rabbits inoculated with the same virus was prompt and reached a high level within 14 to 29 days regardless of the site of inoculation. Long-term persistence of viremia was observed only in intravenously inoculated rabbits; a brief period of viremia was observed in intraperitoneally inoculated rabbits, but no viremia was obtained in rabbits inoculated by the subcutaneous route. Maternal antibody was transferred readily to offspring; however, transference of infectious virus from mother to offspring was demonstrable in only one of 75 fetuses tested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351587"}
{"pmid": "4351589", "title": "Naloxone and the narcotic abuser: a low-dose maintenance program.", "content": "Naloxone and the narcotic abuser: a low-dose maintenance program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351589"}
{"pmid": "4351590", "title": "A calcium-sensitive lanthanum inhibition of amoeboid movement.", "content": "A calcium-sensitive lanthanum inhibition of amoeboid movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351590"}
{"pmid": "4351591", "title": "Colony formation by chicken hematopoietic cells and virus-induced myeloblasts.", "content": "Colony formation by chicken hematopoietic cells and virus-induced myeloblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351591"}
{"pmid": "4351596", "title": "Immune status of children one to four years of age as determined by history and antibody measurement.", "content": "Immune status of children one to four years of age as determined by history and antibody measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351596"}
{"pmid": "4351598", "title": "Conference and workshop on cellular immune reactions to human tumor-associated antigens. Introduction.", "content": "Conference and workshop on cellular immune reactions to human tumor-associated antigens. Introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351598"}
{"pmid": "4351597", "title": "Mechanisms of lithium action.", "content": "Mechanisms of lithium action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351597"}
{"pmid": "4351600", "title": "Neurilemmoma of the facial nerve.", "content": "Neurilemmoma of the facial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351600"}
{"pmid": "4351601", "title": "Effectiveness of extended aftercare in the treatment of alcoholism.", "content": "Effectiveness of extended aftercare in the treatment of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351601"}
{"pmid": "4351607", "title": "Subgroup classification of feline leukemia and sarcoma viruses by viral interference and neutralization tests.", "content": "Subgroup classification of feline leukemia and sarcoma viruses by viral interference and neutralization tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351607"}
{"pmid": "4351608", "title": "Analysis on the reproducing and cell-transforming capacities of a temperature sensitive mutant (ts 334) of avian sarcoma virus B77.", "content": "Analysis on the reproducing and cell-transforming capacities of a temperature sensitive mutant (ts 334) of avian sarcoma virus B77.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351608"}
{"pmid": "4351609", "title": "Immunological characterization of a low molecular weight polypeptide of murine leukemia virus.", "content": "Immunological characterization of a low molecular weight polypeptide of murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351609"}
{"pmid": "4351610", "title": "RNA species obtained from clonal lines of avian sarcoma and from avian leukosis virus.", "content": "RNA species obtained from clonal lines of avian sarcoma and from avian leukosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351610"}
{"pmid": "4351611", "title": "Poly(rI) more important than poly(rC) in the interferon induction process by poly(rI)-poly(rC).", "content": "Poly(rI) more important than poly(rC) in the interferon induction process by poly(rI)-poly(rC).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351611"}
{"pmid": "4351612", "title": "Complementation of transforming functions by temperature-sensitive mutants of avian sarcoma virus.", "content": "Complementation of transforming functions by temperature-sensitive mutants of avian sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351612"}
{"pmid": "4351613", "title": "The synthesis of complementary ribonucleic acid during infection with LSc poliovirus.", "content": "The synthesis of complementary ribonucleic acid during infection with LSc poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351613"}
{"pmid": "4351614", "title": "Characterisation of temperature-sensitive mutants of herpes simplex virus type 2. Growth and DNA synthesis.", "content": "Characterisation of temperature-sensitive mutants of herpes simplex virus type 2. Growth and DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351614"}
{"pmid": "4351615", "title": "A structural model for picornaviruses as suggested from an analysis of urea-degraded virions and procapsids of coxsackievirus B3.", "content": "A structural model for picornaviruses as suggested from an analysis of urea-degraded virions and procapsids of coxsackievirus B3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351615"}
{"pmid": "4351616", "title": "Prophage deletion mapping of bacteriophage Mu-1.", "content": "Prophage deletion mapping of bacteriophage Mu-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351616"}
{"pmid": "4351617", "title": "Cytomegalovirus infection: a seroepidemiologic study of a recruit population.", "content": "Cytomegalovirus infection: a seroepidemiologic study of a recruit population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351617"}
{"pmid": "4351618", "title": "Epidemiologic and clinical observations in six outbreaks of viral disease in a kibbutz, 1968-1971.", "content": "Epidemiologic and clinical observations in six outbreaks of viral disease in a kibbutz, 1968-1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351618"}
{"pmid": "4351619", "title": "Variant angina associated with angiographically demonstrated coronary artery spasm and REM sleep.", "content": "Variant angina associated with angiographically demonstrated coronary artery spasm and REM sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351619"}
{"pmid": "4351620", "title": "Ultrastructural study of two gonadotrophs in rats bearing an adrenocortical carcinoma (Snell 494).", "content": "Ultrastructural study of two gonadotrophs in rats bearing an adrenocortical carcinoma (Snell 494). Two morphologically distinct gonadotrophs have been identified in the anterior pituitary of rats bearing the Snell 494 tumor. Type 1 gonadotrophs first showed ultrastructural alterations at 4 weeks after implantation of the tumor. Numerous large 300 to 600 mmu granules appeared in type 1 cells. The opacity of the granules was variable, and they sometimes contained non-membrane-bounded spherical inclusions. These granules were dispersed among more electron-opaque, 200-mmu granules usually seen in gonadotrophs. A third granule approximately 500 to 600 mmu in diameter was apparently a lysosome-derived structure. Type 2 gonadotrophs first showed changes after 4 weeks, but the alterations were especially prominent by 8 to 10 weeks. No large granules characteristic of type 1 cells were seen in type 2 cells. By 8 to 10 weeks, very few 200-mmu granules were observed in the cytoplasm of type 2 cells. The endoplasmic reticulum was dilated in most type 2 cells; frequently, the cisternae were dilated considerably, forming large lake-like areas. Hypertrophic rough endoplasmic reticulum and the presence of intracisternal granules within cisternae of the rough reticulum suggest that type 2 cells were stimulated by the tumor. Changes in gonadotrophs were undoubtedly produced by the large amount of corticosterone secreted by the tumor. The corticosterone secreted by the tumor. The corticosterone may well act directly on the hypothalamo-hypophyseal axis or it could act indirectly on the ovary; ovarian steroids would then exert a feedback effect. The ovary was atrophic and did not contain maturing Graafian follicles or corpora lutea. In somatotrophs, the number of secretory granules increased, probably reflecting suppression of hormonal release by corticosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351620"}
{"pmid": "4351623", "title": "Virus cross-infection in paediatric wards.", "content": "Virus cross-infection in paediatric wards. In a survey of virus cross-infection in paediatric wards there were 15 cross-infections due to respiratory syncytial (R.S.) virus and 16 due to influenza A, both during a four-month period, and 19 due to parainfluenza viruses over two years. The illnesses produced by these infections acquired in hospital ranged from a slight cold to severe pneumonia: in 17 of the 50 cases the illness involved the lower respiratory tract. A measure of cross-infection frequency in the form of a \"cross-infection rate\" has been devised, and it is suggested that this can be used to assess the influence of factors such as ward design and admission policy on the frequency of cross-infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351623"}
{"pmid": "4351625", "title": "Differences between cerebellar mossy and climbing fibre responses to natural stimulation of forelimb muscle proprioceptors.", "content": "Differences between cerebellar mossy and climbing fibre responses to natural stimulation of forelimb muscle proprioceptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351625"}
{"pmid": "4351626", "title": "Visual cortical units associated with phasic activity in REM sleep and wakefulness.", "content": "Visual cortical units associated with phasic activity in REM sleep and wakefulness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351626"}
{"pmid": "4351624", "title": "Herpes simplex virus type 2 in acute aseptic meningitis.", "content": "Herpes simplex virus type 2 in acute aseptic meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351624"}
{"pmid": "4351627", "title": "Glial metabolism: alteration by potassium levels comparable to those during neural activity.", "content": "Glial metabolism: alteration by potassium levels comparable to those during neural activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351627"}
{"pmid": "4351628", "title": "Enhanced striatal acetylcholine release by chlorpromazine and its reversal by apomorphine.", "content": "Enhanced striatal acetylcholine release by chlorpromazine and its reversal by apomorphine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351628"}
{"pmid": "4351629", "title": "Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus.", "content": "Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351629"}
{"pmid": "4351631", "title": "Propagation of afterdischarges elicited in thin brain sections in artificial media.", "content": "Propagation of afterdischarges elicited in thin brain sections in artificial media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351631"}
{"pmid": "4351633", "title": "Olivo-cochlear inhibition during physostigmine-induced activity in the pontine reticular formation in the decerebrate cat.", "content": "Olivo-cochlear inhibition during physostigmine-induced activity in the pontine reticular formation in the decerebrate cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351633"}
{"pmid": "4351634", "title": "Relationships between pre- and postsynaptic effects of A and C fiber inputs to dorsal horn of M. mulatta.", "content": "Relationships between pre- and postsynaptic effects of A and C fiber inputs to dorsal horn of M. mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351634"}
{"pmid": "4351632", "title": "Effects of neuromuscular activity on choline acetyltransferase and acetylcholinesterase.", "content": "Effects of neuromuscular activity on choline acetyltransferase and acetylcholinesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351632"}
{"pmid": "4351635", "title": "In vivo destruction of tumor cells by an indirect cell-mediated immune mechanism.", "content": "In vivo destruction of tumor cells by an indirect cell-mediated immune mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351635"}
{"pmid": "4351636", "title": "Biological testing of leukaemic lesions of ICRC mice for possible viral activity.", "content": "Biological testing of leukaemic lesions of ICRC mice for possible viral activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351636"}
{"pmid": "4351637", "title": "Delayed effects of a single treatment of hydroxyurea to newborn mice.", "content": "Delayed effects of a single treatment of hydroxyurea to newborn mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351637"}
{"pmid": "4351638", "title": "Comparison of in vitro antiamoebic activity of MK 910 with metronidazole, intestopan and enterovioform.", "content": "Comparison of in vitro antiamoebic activity of MK 910 with metronidazole, intestopan and enterovioform.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351638"}
{"pmid": "4351639", "title": "Antibodies to phospholipids in human tuberculous sera.", "content": "Antibodies to phospholipids in human tuberculous sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351639"}
{"pmid": "4351640", "title": "Basement membrane antigens combining with antisera to human glomerular asement membrane and lymphocytes.", "content": "Basement membrane antigens combining with antisera to human glomerular asement membrane and lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351640"}
{"pmid": "4351642", "title": "Constituents of Cannabis sativa L. 3. Clear and discrete separation of cannabidiol and cannabichromene.", "content": "Constituents of Cannabis sativa L. 3. Clear and discrete separation of cannabidiol and cannabichromene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351642"}
{"pmid": "4351641", "title": "Neoplasm of mixed mesenchymal and neuroepithelial origin: liposarcomatous meningioma combined with gliomas.", "content": "Neoplasm of mixed mesenchymal and neuroepithelial origin: liposarcomatous meningioma combined with gliomas. A case is reported of an intracranial neoplasm of mixed mesenchymal and neuroepithelial (glial) origin occurring in the parieto-parasagittal region of the brain of a 19 year old man. A meningioma with liposarcomatous and psammomatous components comprised the mesenchymal part of the combined tumour. The neuroepithelial portion was composed of mixed ependymoma and astrocytoma. The combined neoplasm had the gross appearances and several microscopic features of giant-celled glioblastoma, giant cell sarcoma, and monstrocellular sarcoma. The findings suggest that these tumours have a mixed mesenchymal and neuroepithelial origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351641"}
{"pmid": "4351644", "title": "The initiation of a \"metabolic window\" in the surface of host erythrocytes by Plasmodium berghei NYU-2.", "content": "The initiation of a \"metabolic window\" in the surface of host erythrocytes by Plasmodium berghei NYU-2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351644"}
{"pmid": "4351643", "title": "False-positive monospot or rubella and mononucleosis.", "content": "False-positive monospot or rubella and mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351643"}
{"pmid": "4351645", "title": "Regulation of cholesterol biosynthesis in rat liver after the administration of N-2-fluorenylacetamide.", "content": "Regulation of cholesterol biosynthesis in rat liver after the administration of N-2-fluorenylacetamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351645"}
{"pmid": "4351646", "title": "Epithelial tumours of the salivary glands.", "content": "Epithelial tumours of the salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351646"}
{"pmid": "4351660", "title": "Brief exposure of bacteria to topical antibiotics.", "content": "Brief exposure of bacteria to topical antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351660"}
{"pmid": "4351661", "title": "Tissue response to ceramic foam dust following intratracheal and intraperitoneal administration.", "content": "Tissue response to ceramic foam dust following intratracheal and intraperitoneal administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351661"}
{"pmid": "4351662", "title": "Effects of drugs or hepatotoxins on the relation between drug-metabolizing activity and phospholipids in hepatic microsomes during choline deficiency.", "content": "Effects of drugs or hepatotoxins on the relation between drug-metabolizing activity and phospholipids in hepatic microsomes during choline deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351662"}
{"pmid": "4351670", "title": "Effects of prostaglandins E 1 , A 1 , and F 2   on renal handling of salt and water.", "content": "Effects of prostaglandins E 1 , A 1 , and F 2   on renal handling of salt and water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351670"}
{"pmid": "4351672", "title": "Micropharmacology of vertebrate neuromuscular transmission.", "content": "Micropharmacology of vertebrate neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351672"}
{"pmid": "4351671", "title": "Control of gluconeogenesis and glycogenolysis in perfused livers of normal mice.", "content": "Control of gluconeogenesis and glycogenolysis in perfused livers of normal mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351671"}
{"pmid": "4351673", "title": "Drug research and human sleep.", "content": "Drug research and human sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351673"}
{"pmid": "4351675", "title": "Radioimmunoassay.", "content": "Radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351675"}
{"pmid": "4351674", "title": "Sympathetic mechanisms in blood vessels: nerve and muscle relationships.", "content": "Sympathetic mechanisms in blood vessels: nerve and muscle relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351674"}
{"pmid": "4351676", "title": "Renal pharmacology, with special emphasis on aldosterone and angiotensin.", "content": "Renal pharmacology, with special emphasis on aldosterone and angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351676"}
{"pmid": "4351678", "title": "Endocrine disorders of growth in stature.", "content": "Endocrine disorders of growth in stature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351678"}
{"pmid": "4351677", "title": "Glucagon infusion following phosphodiesterase inhibition: an experimental study of the hemodynamic effects.", "content": "Glucagon infusion following phosphodiesterase inhibition: an experimental study of the hemodynamic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351677"}
{"pmid": "4351680", "title": "Photodynamic inactivation in the treatment of experimental herpes simplex keratitis.", "content": "Photodynamic inactivation in the treatment of experimental herpes simplex keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351680"}
{"pmid": "4351681", "title": "Epidemic keratoconjuctivitis.", "content": "Epidemic keratoconjuctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351681"}
{"pmid": "4351682", "title": "Stimulation of corticotropin release.", "content": "Stimulation of corticotropin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351682"}
{"pmid": "4351679", "title": "Enzyme activity of antigen-stimulated macrophages.", "content": "Enzyme activity of antigen-stimulated macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351679"}
{"pmid": "4351691", "title": "Mechanism of hypertriglyceridaemia associated with contraceptive steroids.", "content": "Mechanism of hypertriglyceridaemia associated with contraceptive steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351691"}
{"pmid": "4351693", "title": "Effect of collagenase on human growth hormone and ACTH.", "content": "Effect of collagenase on human growth hormone and ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351693"}
{"pmid": "4351692", "title": "A micro-method for the measurement of pharmacologically induced changes in purine derivatives.", "content": "A micro-method for the measurement of pharmacologically induced changes in purine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351692"}
{"pmid": "4351694", "title": "The prevalence of hyperlipidemia in a natural community.", "content": "The prevalence of hyperlipidemia in a natural community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351694"}
{"pmid": "4351696", "title": "Möbius syndrome with Poland's anomaly.", "content": "Möbius syndrome with Poland's anomaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351696"}
{"pmid": "4351695", "title": "A physico-chemical sub-grouping of the mammalian picornaviruses.", "content": "A physico-chemical sub-grouping of the mammalian picornaviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351695"}
{"pmid": "4351697", "title": "Effects of cortisol on evoked potentials and recovery cycles in the rat hypothalamus.", "content": "Effects of cortisol on evoked potentials and recovery cycles in the rat hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351697"}
{"pmid": "4351698", "title": "Malakoplakia: an electron-microscope and chemical study.", "content": "Malakoplakia: an electron-microscope and chemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351698"}
{"pmid": "4351700", "title": "Pituitary-adrenal influences on behavior: responses to test situation with or without electric footshock.", "content": "Pituitary-adrenal influences on behavior: responses to test situation with or without electric footshock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351700"}
{"pmid": "4351701", "title": "The climacteric.", "content": "The climacteric.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351701"}
{"pmid": "4351710", "title": "Cell culture propagated fowl pox vaccine.", "content": "Cell culture propagated fowl pox vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351710"}
{"pmid": "4351712", "title": "A comparative ultrastructural study of the effects of chlorphentermine and triparanol in rat lung and adrenal gland.", "content": "A comparative ultrastructural study of the effects of chlorphentermine and triparanol in rat lung and adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351712"}
{"pmid": "4351716", "title": "Monkeypox and its relevance to smallpox eradication.", "content": "Monkeypox and its relevance to smallpox eradication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351716"}
{"pmid": "4351717", "title": "Virilizing adrenal adenoma.", "content": "Virilizing adrenal adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351717"}
{"pmid": "4351724", "title": "Attempt to influence viral mouse leukaemia by simultaneous infection with influenza A1 virus.", "content": "Attempt to influence viral mouse leukaemia by simultaneous infection with influenza A1 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351724"}
{"pmid": "4351726", "title": "The effect of parachlorophenylalanine on the sleep of a methadone addict.", "content": "The effect of parachlorophenylalanine on the sleep of a methadone addict.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351726"}
{"pmid": "4351728", "title": "Actinomycin D for Wilms's tumour.", "content": "Actinomycin D for Wilms's tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351728"}
{"pmid": "4351727", "title": "'Psychopathia Sexualis'.", "content": "'Psychopathia Sexualis'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351727"}
{"pmid": "4351729", "title": "Temperature-induced phase changes in membranes of heart: a contrast between the thermal response of poikilotherms and homeotherms.", "content": "Temperature-induced phase changes in membranes of heart: a contrast between the thermal response of poikilotherms and homeotherms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351729"}
{"pmid": "4351730", "title": "Using inpatient staff for aftercare of severely disturbed chronic patients.", "content": "Using inpatient staff for aftercare of severely disturbed chronic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351730"}
{"pmid": "4351731", "title": "Malignant hepatoma.", "content": "Malignant hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351731"}
{"pmid": "4351718", "title": "Microbiochemical analysis of the arterial wall. I. Phosphofructokinase.", "content": "Microbiochemical analysis of the arterial wall. I. Phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351718"}
{"pmid": "4351732", "title": "'Sclerosing haemangioma' of the lung: an alternative view of its development.", "content": "'Sclerosing haemangioma' of the lung: an alternative view of its development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351732"}
{"pmid": "4351720", "title": "Studies of the mechanisms of carbohydrate-induced lipaemia in normal man.", "content": "Studies of the mechanisms of carbohydrate-induced lipaemia in normal man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351720"}
{"pmid": "4351722", "title": "Collagen synthesis in thoracic aortas of rabbits with epinephrine-thyroxine induced arteriosclerosis.", "content": "Collagen synthesis in thoracic aortas of rabbits with epinephrine-thyroxine induced arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351722"}
{"pmid": "4351733", "title": "Spin-labeled analogs of local anesthetics.", "content": "Spin-labeled analogs of local anesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351733"}
{"pmid": "4351734", "title": "Synthesis of 5-trifluoromethyl-2'-deoxyuridine 5'-phosphate and 5-trifluoromethyl-2'-deoxyuridine 5'-triphosphate.", "content": "Synthesis of 5-trifluoromethyl-2'-deoxyuridine 5'-phosphate and 5-trifluoromethyl-2'-deoxyuridine 5'-triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351734"}
{"pmid": "4351735", "title": "DNA synthesis in nucleotide-permeable Escherichia coli cells. VII. Conversion of phi chi-174 DNA to its replicative form.", "content": "DNA synthesis in nucleotide-permeable Escherichia coli cells. VII. Conversion of phi chi-174 DNA to its replicative form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351735"}
{"pmid": "4351721", "title": "Functional overlap between \"chylomicra\" and \"very low density lipoproteins\" of human plasma during alimentary lipaemia.", "content": "Functional overlap between \"chylomicra\" and \"very low density lipoproteins\" of human plasma during alimentary lipaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351721"}
{"pmid": "4351736", "title": "Reciprocal effects of change of subunit structure on ligand equilibria of haemoglobin valency hybrids. Attempted correlation with electron paramagnetic resonance spectra.", "content": "Reciprocal effects of change of subunit structure on ligand equilibria of haemoglobin valency hybrids. Attempted correlation with electron paramagnetic resonance spectra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351736"}
{"pmid": "4351723", "title": "An evaluation of cellulose acetate electrophoresis for the determination of human plasma lipoprotein patterns.", "content": "An evaluation of cellulose acetate electrophoresis for the determination of human plasma lipoprotein patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351723"}
{"pmid": "4351737", "title": "Electron paramagnetic studies of nitric oxide haemoglobin derivatives: isolated subunits and nitric oxide hybrids.", "content": "Electron paramagnetic studies of nitric oxide haemoglobin derivatives: isolated subunits and nitric oxide hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351737"}
{"pmid": "4351738", "title": "Interaction between lambda or phi80 prophage induction and gal operon expression.", "content": "Interaction between lambda or phi80 prophage induction and gal operon expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351738"}
{"pmid": "4351739", "title": "\"Polymyositis\" with involvement of facial and distal musculature. One form of the fascioscapulohumeral syndrome?", "content": "\"Polymyositis\" with involvement of facial and distal musculature. One form of the fascioscapulohumeral syndrome?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351739"}
{"pmid": "4351741", "title": "Anxiety as a manifestation of associated drives and events in a female schizophrenic patient.", "content": "Anxiety as a manifestation of associated drives and events in a female schizophrenic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351741"}
{"pmid": "4351750", "title": "Unilateral ureteral obstruction. A caue of reversible high renin content hypertension.", "content": "Unilateral ureteral obstruction. A caue of reversible high renin content hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351750"}
{"pmid": "4351751", "title": "Uptake and effect of 17 -estradiol on pineal hydroxy-indole-O-methyl transferase (HIOMT) activity.", "content": "Uptake and effect of 17 -estradiol on pineal hydroxy-indole-O-methyl transferase (HIOMT) activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351751"}
{"pmid": "4351740", "title": "Mental health nursing consultations: some distinctions.", "content": "Mental health nursing consultations: some distinctions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351740"}
{"pmid": "4351752", "title": "Thyroidal K + -activated p-nitrophenylphosphatase activity.", "content": "Thyroidal K + -activated p-nitrophenylphosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351752"}
{"pmid": "4351745", "title": "Speaking out on: second career adds to nurse supply.", "content": "Speaking out on: second career adds to nurse supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351745"}
{"pmid": "4351742", "title": "The yellow brick road: a legitimate educational pursuit.", "content": "The yellow brick road: a legitimate educational pursuit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351742"}
{"pmid": "4351756", "title": "Two distinct antigenic components in an Epstein-Barr virus-related early product induced by halogenated pyrimidines in non-producing human lymphoblastoid cells.", "content": "Two distinct antigenic components in an Epstein-Barr virus-related early product induced by halogenated pyrimidines in non-producing human lymphoblastoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351756"}
{"pmid": "4351754", "title": "Non-repetitive DNA transcription in mouse cells grown in tissue culture.", "content": "Non-repetitive DNA transcription in mouse cells grown in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351754"}
{"pmid": "4351743", "title": "Development of the co-therapy relationship.", "content": "Development of the co-therapy relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351743"}
{"pmid": "4351755", "title": "Polyadenylate synthesis by extracts from L cells infected with vesicular stomatitis virus.", "content": "Polyadenylate synthesis by extracts from L cells infected with vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351755"}
{"pmid": "4351757", "title": "Quantitative determination of drugs by means of densitometry of thin-layer chromatograms. 3. Determination of vitamins D 2  and D 3  in oil and aqueous injection solutions in the presence of decomposition products.", "content": "Quantitative determination of drugs by means of densitometry of thin-layer chromatograms. 3. Determination of vitamins D 2  and D 3  in oil and aqueous injection solutions in the presence of decomposition products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351757"}
{"pmid": "4351747", "title": "Delivery of mental health services to children of \"resistive\" parents.", "content": "Delivery of mental health services to children of \"resistive\" parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351747"}
{"pmid": "4351744", "title": "Mental illness and the state (Roche report).", "content": "Mental illness and the state (Roche report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351744"}
{"pmid": "4351746", "title": "Psychiatric drugs and trends: long acting tranquilizer.", "content": "Psychiatric drugs and trends: long acting tranquilizer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351746"}
{"pmid": "4351760", "title": "Abrasive blasting protective practices study--preliminary survey results.", "content": "Abrasive blasting protective practices study--preliminary survey results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351760"}
{"pmid": "4351758", "title": "Leprosy--an alternative viewpoint.", "content": "Leprosy--an alternative viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351758"}
{"pmid": "4351762", "title": "Alexia without agraphia or hemianopsia. Anatomical analysis of an autopsied case.", "content": "Alexia without agraphia or hemianopsia. Anatomical analysis of an autopsied case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351762"}
{"pmid": "4351761", "title": "The effect of pyrimidine compounds on the potentiation of adenosine inhibition of aggregation, on adenosine phosphorylation and phosphodiesterase activity of blood platelets.", "content": "The effect of pyrimidine compounds on the potentiation of adenosine inhibition of aggregation, on adenosine phosphorylation and phosphodiesterase activity of blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351761"}
{"pmid": "4351763", "title": "Hyperlipaemic neuropathy, Experimental study.", "content": "Hyperlipaemic neuropathy, Experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351763"}
{"pmid": "4351749", "title": "Small group method on a general hospital nursing unit.", "content": "Small group method on a general hospital nursing unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351749"}
{"pmid": "4351748", "title": "Leisure time for the elderly.", "content": "Leisure time for the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351748"}
{"pmid": "4351765", "title": "Genetic influence on the renin-angiotensin system: low renin activities in hypertension-prone rats.", "content": "Genetic influence on the renin-angiotensin system: low renin activities in hypertension-prone rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351765"}
{"pmid": "4351766", "title": "Intrarenal role of angiotensin II. Homeostatic regulation of renal blood flow in the dog.", "content": "Intrarenal role of angiotensin II. Homeostatic regulation of renal blood flow in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351766"}
{"pmid": "4351767", "title": "Variations in adrenergic innervation and contractile responses of the rabbit saphenous artery.", "content": "Variations in adrenergic innervation and contractile responses of the rabbit saphenous artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351767"}
{"pmid": "4351768", "title": "The sudden infant death syndrome.", "content": "The sudden infant death syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351768"}
{"pmid": "4351770", "title": "The action and interaction of diphenhydramine (Benadryl) hydrochloride at the neuromuscular junction.", "content": "The action and interaction of diphenhydramine (Benadryl) hydrochloride at the neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351770"}
{"pmid": "4351772", "title": "Studies about unconjugated androstenediol in human peripheral plasma.", "content": "Studies about unconjugated androstenediol in human peripheral plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351772"}
{"pmid": "4351771", "title": "Measurement of plasma renin substrate by radioimmunoassay of angiotensin. I. Concentration in syndromes associated with steroid excess.", "content": "Measurement of plasma renin substrate by radioimmunoassay of angiotensin. I. Concentration in syndromes associated with steroid excess. Plasma renin substrate (PRS) and plasma renin activity (PRA) were measured by radioimmunoassay of generated angiotension I in normal subjects and patients with steroid excess syndromes.  In subjects with Cushing's syndrome, glucocorticosteroid therapy and oral contraceptive agents or estrogens, significant elevations of plasma renin substrate was observed.  Only in subjects with primary aldosteronism was the plasma renin activity significantly supressed.  The significance of elevations of PRS was assessed by determining the Km of the plasma renin-substrate reaction at physiologic pH.  The apparent Km for the reaction was 1000 ng Angiotension I in PRS units.  Correction of measured PRA to a standardized PRA was achieved by calculation of the reaction rate that would occur at the mean normal PRS concentration of 1100 ng/ml.  Results indicate that elevations of PRS which occur in Cushing's syndrome or with administration of glucocorticoids, oral contraceptive agents, or estrogens are sufficient to significantly elevate the renin substrate reaction in plasma.  In contrast, glucocorticoid excess appears not to suppress plasma renin activity even when reaction rates are corrected for increased PRS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351771"}
{"pmid": "4351773", "title": "Effect of hypopituitarism and ACTH on the urinary excretion of norepinephrine in man.", "content": "Effect of hypopituitarism and ACTH on the urinary excretion of norepinephrine in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351773"}
{"pmid": "4351774", "title": "Adenosine 3',5'-monophosphate in amniotic fluid from normal pregnancy.", "content": "Adenosine 3',5'-monophosphate in amniotic fluid from normal pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351774"}
{"pmid": "4351776", "title": "Effect of hydrocortisone and corticotropin on glucose-induced insulin and proinsulin secretion in man.", "content": "Effect of hydrocortisone and corticotropin on glucose-induced insulin and proinsulin secretion in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351776"}
{"pmid": "4351775", "title": "Nocturnal patterns of serum gonadotropins during the menstrual cycle.", "content": "Nocturnal patterns of serum gonadotropins during the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351775"}
{"pmid": "4351777", "title": "Dexamethasone-suppressible hyperaldosteronism.", "content": "Dexamethasone-suppressible hyperaldosteronism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351777"}
{"pmid": "4351778", "title": "Inference of refractory period, temporal summation, and adaptation from behavior in chronic implants: midbrain pain systems.", "content": "Inference of refractory period, temporal summation, and adaptation from behavior in chronic implants: midbrain pain systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351778"}
{"pmid": "4351779", "title": "Behavioral measurements of the neural poststimulation excitability cycle in the lateral hypothalamic eating system of the rat.", "content": "Behavioral measurements of the neural poststimulation excitability cycle in the lateral hypothalamic eating system of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351779"}
{"pmid": "4351780", "title": "The role of type specific and cross reacting structural antigens in the neutralization of herpes simplex virus types 1 and 2.", "content": "The role of type specific and cross reacting structural antigens in the neutralization of herpes simplex virus types 1 and 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351780"}
{"pmid": "4351781", "title": "Further evidence for two loci which control susceptibility of fowl to RSV(RAV-O).", "content": "Further evidence for two loci which control susceptibility of fowl to RSV(RAV-O).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351781"}
{"pmid": "4351782", "title": "2,3-Erythro-dihydroxyhexacosanoic acid and homologs: isolation from yeast cerebrin phosphate and determination of their structures.", "content": "2,3-Erythro-dihydroxyhexacosanoic acid and homologs: isolation from yeast cerebrin phosphate and determination of their structures. Homologs of methyl esters of very polar fatty acids were obtained by methanolysis of cerebrin phosphate isolated from baker's yeast. The major ester component was isolated by preparative gas-liquid chromatography and was found to be 2,3-dihydroxyhexacosanoic acid as deduced from the mass spectra of its trimethylsilyl ether and isopropylidene derivative, reaction with periodate, and comparison of its chromatographic behavior with that of synthetic erythro- and threo-dihydroxy acids. Its infrared spectrum supported the above conclusions. From their retention times by gas-liquid chromatography, the homologs were found to be saturated, unbranched 2,3-dihydroxy fatty acids with 24-27 carbon atoms. The synthesis of the new fatty acids, erythro- and threo-2,3-dihydroxyhexacosanoic acids, is also reported. A method for separating trans-2-hexacosenoic acid, a key intermediate of the above synthesis, and its isomer, trans-3-hexacosenoic acid, both formed by dehydrobromination of 2-bromohexacosanoic acid, is also described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351782"}
{"pmid": "4351783", "title": "Metabolic fate of rat and human lipoprotein apoproteins in the rat.", "content": "Metabolic fate of rat and human lipoprotein apoproteins in the rat. The fate of (125)I-labeled apolipoproteins was studied in vivo in rats that had received intravenous injections of (125)I-labeled rat HDL and (125)I-labeled human HDL, LDL, and VLDL. Plasma decay curves of rat and human HDL were exponential with similar half-lives in the circulation (11-12 hr). After injection, low molecular weight apolipoproteins (apoLP-alanine of human HDL and fraction HS-3 of rat HDL) were found to redistribute to other lipoproteins, predominantly VLDL. Decay curves of individual HDL proteins were constructed after lipoprotein fractionation, delipidation, and polyacrylamide gel electrophoresis. It was found that the half-lives of the different HDL apoproteins were not identical. A major rat HDL protein (52% of total counts) had a circulating half-life (t((1/2))) of 12.5 hr. Two others had a t((1/2)) of 8-9 hr while the t((1/2)) of several others was 11-12 hr. The t((1/2)) of three well-characterized human HDL apoproteins, apoLP-glutamine I, apoLP-glutamine II, and apoLP-alanine, were 13.5, 9.0, and 15.0 hr, respectively. The fate of (125)I-labeled human VLDL and LDL apoproteins in rats was similar to that described previously in humans. After injection of (125)I-labeled human VLDL into rats, apoLP-glutamic acid and apoLP-alanine rapidly transferred to rat HDL and were lost thereafter from the circulation from both VLDL and HDL. The apoLDL moiety of human VLDL moved metabolically to the LDL density range (d = 1.019-1.063) through a lipoprotein of intermediate density (d = 1.006-1.019).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351783"}
{"pmid": "4351784", "title": "Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta.", "content": "Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta. Homogenates and subcellular fractions of the intimamedia of hog aorta have been prepared and examined for the presence of the enzymes catalyzing the conversion of acetyl CoA to squalene. Enzyme activities effecting the conversion of acetyl CoA to 3-hydroxy-3-methylglutarate (HMG); HMG CoA to mevalonic acid; mevalonic acid to 5-phosphomevalonic acid, 5-pyrophosphomevalonic acid, and isopentenyl pyrophosphate; isopentenyl pyrophosphate to farnesyl pyrophosphate; and farnesyl pyrophosphate to squalene have been demonstrated in these homogenates. The overall conversion of mevalonate to squalene has also been demonstrated with recombined fractions of hog aorta homogenates. Data are also presented that suggest that phosphatases present in the crude homogenates act to cleave farnesyl pyrophosphate to farnesol, and phospho- and pyrophosphomevalonate to mevalonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351784"}
{"pmid": "4351786", "title": "Release of transmitters into the perfused third cerebral ventricle.", "content": "Release of transmitters into the perfused third cerebral ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351786"}
{"pmid": "4351787", "title": "Evoked transmitter release at the frog neuromuscular junction in very low calcium solutions.", "content": "Evoked transmitter release at the frog neuromuscular junction in very low calcium solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351787"}
{"pmid": "4351785", "title": "A comparison of the effects of adenosine triphosphate with noradrenaline and with the inhibitory potential of the guinea-pig taenia coli.", "content": "A comparison of the effects of adenosine triphosphate with noradrenaline and with the inhibitory potential of the guinea-pig taenia coli. 1. The response of the smooth muscle of the guinea-pig taenia coli to adenosine triphosphate (ATP) and related substances was compared with that to noradrenaline and dopamine. The effect of these substances on the inhibitory potential was investigated.2. ATP in concentration of 10(-6)-10(-5)M suppressed the spontaneous spike and relaxed the preparation. ATP in a concentration higher than 10(-4)M hyperpolarized the membrane, reduced the membrane resistance and decreased the inhibitory potential.3. Effects of noradrenaline (5 x 10(-6)M) and of dopamine (5 x 10(-4)M) were similar to those of ATP (10(-3)M). However, the effects of catecholamines were reduced in Cl-deficient solution and blocked by phentolamine (3.5 x 10(-6)M), while the effects of ATP were unaffected.4. A high concentration of phentolamine (3.5 x 10(-4)M) almost abolished the inhibitory potential as well as the effects of ATP. The inhibitory potential and the effect of high concentration of ATP (10(-3)M) were not impaired by imidazole (50 mM).5. Adenosine diphosphate, adenosine monophosphate and adenosine produced effects essentially similar to those of ATP. However, their potency was less compared with ATP.6. These electrophysiological observations support the hypothesis that ATP may be the transmitter of the non-adrenergic inhibitory nerves in the taenia coli. No evidence against the hypothesis was obtained.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351785"}
{"pmid": "4351788", "title": "Advances in lipoprotein research: biochemical and clinical aspects.", "content": "Advances in lipoprotein research: biochemical and clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351788"}
{"pmid": "4351790", "title": "Biochemical mechanisms in myelin deficient mutants.", "content": "Biochemical mechanisms in myelin deficient mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351790"}
{"pmid": "4351791", "title": "Adenosine release from isolated fat cells and its significance for the effects of hormones on cyclic 3',5'-AMP levels and lipolysis.", "content": "Adenosine release from isolated fat cells and its significance for the effects of hormones on cyclic 3',5'-AMP levels and lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351791"}
{"pmid": "4351798", "title": "Sugar transport in normal and Rous sarcoma virus-transformed chick-embryo fibroblasts.", "content": "Sugar transport in normal and Rous sarcoma virus-transformed chick-embryo fibroblasts. 3-O-methylglucose (3-OMeG) is a nonmetabolizable glucose analog and is, therefore, suitable for transport studies. 3-OMeG and glucose compete for entry into normal and Rous sarcoma virus (RSV)-transformed chick-embryo fibroblasts. Therefore, 3-OMeG can be used to study the transport of glucose in these cells. Chickembryo fibroblasts infected and transformed by RSV take up 3-OMeG at a faster rate than uninfected cells when both cell types are growing at the same rate. The rate of efflux of 3-OMeG also increases after transformation. When the uptake and the efflux reach a steady state, the intracellular concentration of 3-OMeG is equal to the concentration in the medium. This finding indicates that glucose is transported across the plasma membrane by facilitated diffusion. The V(max) of the transport system for 3-OMeG increases after transformation, while the affinity or K(m) of the system remains unchanged. We conclude that viral transformation causes a change in the plasma membrane of the infected cells by increasing either the number of molecules or the mobility of the glucose carrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351798"}
{"pmid": "4351799", "title": "Conversion of neutral to alkaline liver fructose 1,6-bisphosphatase: changes in molecular properties of the enzyme.", "content": "Conversion of neutral to alkaline liver fructose 1,6-bisphosphatase: changes in molecular properties of the enzyme. Removal of the NH(2)-terminal region of fructose 1,6-bisphosphatase from rabbit liver by digestion with subtillisin, or changes in conformation in this region of the protein produced by exposure to low concentrations of urea, result in similar changes in catalytic and allosteric properties of the enzyme. These changes include shift of the pH optimum to more alkaline pH, and loss of sensitivity to inhibition by AMP. The conformation changes are monitored by changes in the fluorescence of the single tryptophan residue, which is located near the NH(2)-terminus. Thus, the tryptophan-containing peptide appears to determine the functional properties of the native enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351799"}
{"pmid": "4351800", "title": "Roles of calcium, serum, plasma, and folic acid in the control of proliferation of normal and Rous sarcoma virus-infected chicken fibroblasts.", "content": "Roles of calcium, serum, plasma, and folic acid in the control of proliferation of normal and Rous sarcoma virus-infected chicken fibroblasts. In a culture medium of pH 7.4 and a folic acid concentration of 100 mug/liter that contains 5% heat-inactivated chicken plasma rather than serum, the rate of proliferation of normal chicken fibroblasts is determined by the concentration of calcium. Proliferation, rapid when the calcium concentration is physiological, decreases when the calcium concentration is reduced. At a very low calcium concentration, in this culture medium, normal fibroblasts are maintained without proliferation, whereas those infected with Rous sarcoma virus proliferate rapidly. This proliferative inactivity of normal fibroblasts does not involve contact-inhibition, since the effect is observed at low, as well as higher, culture densities. When a physiological amount of calcium is added to cultures of normal fibroblasts that have been maintained in very low calcium-plasma medium for 3 days, labeled thymidine uptake and protein synthesis are strongly stimulated, and cell division follows. The use of heat-inactivated chicken serum, instead of plasma, in this medium appears to strongly sensitize normal fibroblasts to the mitogenic action of calcium. In a plasma-containing culture medium of physiological calcium concentration and a folate concentration of 5 mug/liter, neither normal nor Rous sarcoma virus-infected fibroblasts proliferate to an appreciable extent. The use of serum, however, instead of plasma results in rapid proliferation of both normal and infected cells, as does increase in the folate concentration of the plasma-containing medium to 100 mug/liter.The fact that while normal fibroblasts are maintained without proliferation in low calcium-plasma medium, Rous sarcoma virus-infected fibroblasts proliferate rapidly, indicates that the effect of calcium is regulatory rather than permissive. These results suggest that the proliferation of normal fibroblasts is initiated by a cellular function involving calcium, and that the autonomous proliferation of the neoplastic fibroblasts results either from increased calcium uptake or from an alteration or a hypass of that function. The results also suggest that serum contains a mitogenic factor(s) not present in plasma, possibly a \"wound hormone\" for fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351800"}
{"pmid": "4351802", "title": "Demonstration of a cell-surface antigen associated with murine sarcoma virus by immunoelectron microscopy.", "content": "Demonstration of a cell-surface antigen associated with murine sarcoma virus by immunoelectron microscopy. Cells transformed by murine sarcoma virus have been examined for the presence of a new virus-associated cell-surface antigen by immunoelectron microscopy. A common antigen has been detected on the surface of nonproductively transformed cells that were induced by two different strains of murine sarcoma virus, Kirsten and Moloney. This antigen shows crossreaction with cell lines transformed by murine sarcoma virus that were produced in two different mammalian species, rats and mice. Further, this antigen is distinct from previously described antigens on the surfaces of cells infected by murine leukemia virus, on the viral envelope, and on the surfaces of spontaneously transformed cell lines or cell lines transformed by x-irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351802"}
{"pmid": "4351801", "title": "Nucleation, rapid folding, and globular intrachain regions in proteins.", "content": "Nucleation, rapid folding, and globular intrachain regions in proteins. Distinct structural regions have been found in several globular proteins composed of single polypeptide chains. The existence of such regions and the continuity of peptide chain within them, coupled with kinetic arguments, suggests that the early stages of three-dimensional structure formation (nucleation) occur independently in separate parts of these molecules. A nucleus can grow rapidly by adding peptide chain segments that are close to the nucleus in aminoacid sequence. Such a process would generate three-dimensional (native) protein structures that contain separate regions of continuous peptide chain. Possible means of testing this hypothesis are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351801"}
{"pmid": "4351803", "title": "Pineal protein kinase: effect of enzymic phosphorylation on actinomycin D binding by, and template activity of, chromatin.", "content": "Pineal protein kinase: effect of enzymic phosphorylation on actinomycin D binding by, and template activity of, chromatin. The ability of protein kinase from bovinepineal gland to phosphorylate calf-thymus chromatin and thereby to alter the association between chromatin DNA and histones was investigated. Phosphorylation of calf-thymus chromatin by pineal protein kinase results in an apparent decreased binding between the histones and DNA in chromatin, as indicated by (i) an increase in actinomycin D-binding sites after phosphorylation and (ii) an increase in the template capacity of the calf-thymus chromatin after phosphorylation. F(1) histone and F(3) histone are the major histone classes in the chromatin that are phosphorylated by the protein kinase. These results support the hypothesis that pineal protein kinase may function at the transcriptional level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351803"}
{"pmid": "4351805", "title": "Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants.", "content": "Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants. The nematode Caenorhabditis elegans is attracted by at least four classes of attractants: by cyclic nucleotides, cAMP and cGMP; by anions, Cl(-), Br(-), I(-); by cations, Na(+), Li(+), K(+), Mg(+); and by alkaline pH values. The nematode's behavioral response to gradients of these attractants involves orientation and movement up the gradient, accumulation, and then habitutation. Comparison of the tracks of wild-type and mutant animals responding to gradients of attractants indicates that sensory receptors in the head alone mediate the orientation response and that the direction of orientation is determined by the lateral motion of the head. Therefore, the orientation response is a klinotaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351805"}
{"pmid": "4351804", "title": "Affinity binding of intact fat cells and their ghosts to immobilized insulin.", "content": "Affinity binding of intact fat cells and their ghosts to immobilized insulin. Immobilized insulin, prepared by coupling insulin directly to agarose or through hydrocarbon \"connecting arms,\" was demonstrated to be capable of firmly binding intact adipocytes and their ghosts. Various lines of evidence indicate that the insulin receptor on the plasma membrane, in addition to the insulin coupled to the agarose, was responsible for the observed binding. This evidence includes: (a) the finding that increasing the \"arm\" length increased the binding capacities of insulin-Sepharose affinity chromatographic columns, (b) specific inhibition and reversal by insulin and antiserum to insulin of the binding, as compared to lesser effects by other peptide hormones, (c) the indication that only the plasma membrane sacs, not the other cellular contaminants in the crude ghosts, are capable of binding, and (d) the impairment and restoration of trypsin-sensitive membrane binding sites that are also required for insulin biosensitivity. These findings support the idea that the insulin receptor is the trypsin-sensitive site. By use of the differential buoyant densities of the various cell-bead complexes that resulted from the interaction of adipocytes with insulin-Sepharose, a new procedure was developed to demonstrate and study the binding. These complexes could also be demonstrated by interference contrast microscopy. Binding readily occurred under conditions favorable for insulin stimulation of the cells. By coupling tracer amounts of [(125)I]insulin to Sepharose or insulin-Sepharose, the effects of anti-insulin antisera, free insulin, and other peptide hormones and supplemental factors on the buoyant-density distribution of the complexes could be measured, as well as the effects of other ligands coupled to Sepharose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351804"}
{"pmid": "4351806", "title": "Carbohydrate catabolism and the enhancement of uptake of galactose in hamster cells transformed by polyoma virus.", "content": "Carbohydrate catabolism and the enhancement of uptake of galactose in hamster cells transformed by polyoma virus. Untransformed as well as polyoma virus-transformed hamster cells can be grown equally well on a slow catabolite like galactose as on a rapid catabolite like glucose. The rate of uptake of galactose is greatly enhanced in the transformed cells as compared with untransformed cells, and this enhancement of entry was as markedly expressed in galactose-grown cultures as in glucose-grown cultures. Since the transformed cultures grown in glucose medium consume practically all of their carbohydrate, contrary to the galactose-grown cultures, problems dealing with regulation of transport by substrate concentrations have to be dealt with also. The galactose captured by the cells accumulates initially as galactose, alpha-galactose-1-phosphate, and UDP-galactose. However, after a 24-hr growth on a galactose growth medium, the product accumulated was almost exclusively galactitol. In spite of the enhancement of entry of galactose into the transformed cells, the metabolic pathway becomes stalled even before it has reached the stage of glucose-1-phosphate, largely due to a choke of the enzyme UDP-galactose-4-epimerase (EC 5.1.3.2). Among the sparse amounts of catabolic products generated by the transformed cells from galactose, carbon dioxide (allebeit no D-xylose) and lactic acid were found, both of them in much smaller amounts than seen if glucose is the carbohydrate source. Also, growth of transformed cells on a galactose medium gradually tends to become oriented, a phenomenon that could be called \"contact promotion.\" Subsequent addition of glucose disturbs the oriented growth and interferes with contact promotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351806"}
{"pmid": "4351807", "title": "Cytochalasin B: effect on lysosomal enzyme release from human leukocytes.", "content": "Cytochalasin B: effect on lysosomal enzyme release from human leukocytes. The morphological and biochemical consequences of treatment of human peripheral blood leukocytes with cytochalasin B were studied. Incubation of human polymorphs with cytochalasin B resulted in nuclear and cytoplasmic spreading, but not in spontaneous release of lysosomal enzymes. Cytochalasin B inhibited particle uptake. Consequently, phagocytic vacuoles were not observed; instead, granule contents were discharged directly into the surrounding medium when cytochalasin B-treated cells were challenged with zymosan particles. Cytochalasin B enhanced the release of lysosomal enzymes from human polymorphonuclear leukocytes whether these encountered zymosan particles or immune complexes on a nonphagocytosable Millipore filter. Cytochalasin B-treated leukocytes thus constitute a model system for quantitative study of lysosome fusion. Augmented enzyme release was blocked by prior treatment of cells with pharmacological doses of agents that influence the accumulation of cyclic nucleotides (cyclic nucleotides themselves, prostaglandin E(1)) or by compounds that interfere with microtubule function (e.g., colchicine, vinblastine). These observations suggest that one action of cytochalasin B on phagocytic cells is to remove the normal constraints to merger of granules, either with each other or with the plasma membrane, and that intact microtubule function is required for translocation of lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351807"}
{"pmid": "4351808", "title": "Minor base composition of \"70S-associated\" 4S RNA from avian myeloblastosis virus.", "content": "Minor base composition of \"70S-associated\" 4S RNA from avian myeloblastosis virus. Using a chemical isotope derivative method, we have determined the minor base composition of the \"70S-associated\" 4S RNA isolated from avian myeloblastosis virus. The minor base composition of this \"70S-associated\" 4S RNA is strikingly similar to that of the corresponding \"free\" 4S RNA of the virion. This minor base content, plus the capacity to esterify amino acids, establishes that both of these virion 4S RNA fractions contain transfer RNA. The percentage of minor bases in virion \"70S-associated\" 4S RNA is, however, much lower than in \"free\" 4S virion RNA and in myeloblast 4S RNA. The implication is that the \"70S-associated\" 4S RNA fraction as isolated herein also contains RNA that is not transfer RNA. This latter RNA may represent either degradation products of high molecular weight RNA or indigenous 4S RNA of undetermined function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351808"}
{"pmid": "4351809", "title": "Regulation of phosphorylation of a specific protein in toad-bladder membrane by antidiuretic hormone and cyclic AMP, and its possible relationship to membrane permeability changes.", "content": "Regulation of phosphorylation of a specific protein in toad-bladder membrane by antidiuretic hormone and cyclic AMP, and its possible relationship to membrane permeability changes. Phosphorylation of a specific protein was decreased in intact toad bladders by exposure to either antidiuretic hormone or monobutyryl cyclic AMP. The decrease in phosphorylation caused by these agents preceded the change in electrical potential difference (an indicator of the rate of sodium ion transport) observed in response to the same compounds. The addition of cyclic AMP to homogenates of toad bladder led to a decrease in phosphorylation of the same, or a similar, protein. In subcellular fractionation studies, the effect of cyclic AMP on the phosphorylation of this protein was observed in those fractions rich in membrane fragments, but not in the nuclear or cell-sap fractions. These and other results are compatible with the possibility that the regulation by vasopressin and cyclic AMP of sodium and/or water transport in toad bladder may be mediated through regulation of the phosphorylation of this specific protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351809"}
{"pmid": "4351810", "title": "A transmissible plasmid controlling camphor oxidation in Pseudomonas putida.", "content": "A transmissible plasmid controlling camphor oxidation in Pseudomonas putida. Earlier papers demonstrated an extensive genetic exchange among fluorescent Pseudomonads; this one documents for genes specifying enzymes of peripheral dissimilation an extrachromosomal array, segregation, and frequent interstrain transfer. An hypothesis is presented of a general mechanism for the formation and maintenance of metabolic diversity. The example used, the path of oxidative cleavage of the carbocyclic rings of the bicyclic monoterpene D- and L-camphor, terminates in acetate release and isobutyrate chain debranching. By transduction, two gene linkage groups are shown for the reactions before and after isobutyrate. The group for reactions before isobutyrate is plasmid borne, contransferable by conjugation, mitomycin curable, and shows a higher segregation rate from cells that are multiplasmid rather than carrying a single plasmid. The genes that code for isobutyrate and essential anaplerotic and amphibolic metabolism are chromosomal. By conjugation plasmid-borne genes are transferred at a higher frequency than are chromosomal, and are transferred in homologous crosses more frequently than between heterologous species. Most isobutyrate-positive fluorescent pseudomonad strains will accept and express the camphor plasmid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351810"}
{"pmid": "4351811", "title": "Acetylcholine receptor and ion conductance modulator sites at the murine neuromuscular junction: evidence from specific toxin reactions.", "content": "Acetylcholine receptor and ion conductance modulator sites at the murine neuromuscular junction: evidence from specific toxin reactions. The perhydro derivative of histrionicotoxin reversibly blocks the excitatory ionic transduction system in the synaptic and sarcolemmal membranes of mammalian skeletal muscle cells. The efficacy of perhydrohistrionicotoxin as an antagonist at the post-synaptic membrane is increased by the transient presence of acetylcholine in the endplate of innervated muscles and at extrajunctional receptors in denervated muscles. alpha-Bungarotoxin and [(3)H]monoacetyl-alpha-bungarotoxin block the endplate acetylcholine receptors, each binding to the same extent. The effect of bungarotoxin is partially reversible. These electrophysiological results, together with the effects of perhydrohistrionicotoxin and/or d-tubocurarine on the binding of [(3)H]monoacetyl-alpha-bungarotoxin at endplates of murine diaphragm muscle and on the bungarotoxin-elicited irreversible blockade of neuromuscular transmission, suggest that at least two types of sites participate in the synaptic excitation by acetylcholine. One site, competitively blocked by bungarotoxin and by curare, is presumably the acetylcholine receptor. Binding of bungarotoxin at this site is responsible for an irreversible blockade of neuromuscular transmission. The second site, competitively blocked by bungarotoxin and perhydrohistrionicotoxin, is proposed to be part of the cholinergic ion conductance modulator. Binding of bungarotoxin to this site does not result in an irreversible blockade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351811"}
{"pmid": "4351814", "title": "Clinical management of advanced gastrointestinal cancer.", "content": "Clinical management of advanced gastrointestinal cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351814"}
{"pmid": "4351817", "title": "Venoms and enzymes: effects of permeability of isolated single electroplax.", "content": "Venoms and enzymes: effects of permeability of isolated single electroplax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351817"}
{"pmid": "4351816", "title": "Biological activities contaminating preparations of phospholipase C ( -toxin) from Clostridium perfringens.", "content": "Biological activities contaminating preparations of phospholipase C ( -toxin) from Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351816"}
{"pmid": "4351818", "title": "Isolation of Gymnodinium breve toxin from Florida red tide water.", "content": "Isolation of Gymnodinium breve toxin from Florida red tide water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351818"}
{"pmid": "4351819", "title": "Colchicine in avian sodium urate and calcium pyrophosphate microcrystal arthritis.", "content": "Colchicine in avian sodium urate and calcium pyrophosphate microcrystal arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351819"}
{"pmid": "4351820", "title": "Application of the technique os isoelectric focusing to the study of human serum lipoproteins and their apoproteins.", "content": "Application of the technique os isoelectric focusing to the study of human serum lipoproteins and their apoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351820"}
{"pmid": "4351815", "title": "Activity of glucoso-6-phosphage gluconeogenesis and dehydrogenase enzymes in fertilized and unfertilized loach ova.", "content": "Activity of glucoso-6-phosphage gluconeogenesis and dehydrogenase enzymes in fertilized and unfertilized loach ova.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351815"}
{"pmid": "4351821", "title": "Proliferation of vesicular stomatitis virus in leucocytes from rheumatoid patients.", "content": "Proliferation of vesicular stomatitis virus in leucocytes from rheumatoid patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351821"}
{"pmid": "4351822", "title": "Clinical and laboratory aspects of raised virus antibody titres in systemic lupus erythematosus.", "content": "Clinical and laboratory aspects of raised virus antibody titres in systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351822"}
{"pmid": "4351823", "title": "Effect of some adrenal steroid hormones on skin fibroblast replication in vitro.", "content": "Effect of some adrenal steroid hormones on skin fibroblast replication in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351823"}
{"pmid": "4351824", "title": "2',3'-Cyclic nucleotide 3'-phosphohydrolase in the developing human brain.", "content": "2',3'-Cyclic nucleotide 3'-phosphohydrolase in the developing human brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351824"}
{"pmid": "4351827", "title": "Direct stimulant effect of cyclic AMP and dibutryl cAMP on glycogenolysis by hepatocytes in histiotypic culture.", "content": "Direct stimulant effect of cyclic AMP and dibutryl cAMP on glycogenolysis by hepatocytes in histiotypic culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351827"}
{"pmid": "4351826", "title": "Human erythrocyte phosphoribosylpyrophosphate synthetase mutationally altered in regulatory properties.", "content": "Human erythrocyte phosphoribosylpyrophosphate synthetase mutationally altered in regulatory properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351826"}
{"pmid": "4351828", "title": "Activation of endogenous C-type on oncornavirus by 5-bromodeoxyuridine in cultured embryonic rat fibroblasts.", "content": "Activation of endogenous C-type on oncornavirus by 5-bromodeoxyuridine in cultured embryonic rat fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351828"}
{"pmid": "4351830", "title": "Comment on Wei's theory of synaptic conduction.", "content": "Comment on Wei's theory of synaptic conduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351830"}
{"pmid": "4351831", "title": "Preganglionic sympathetic activity and baroreceptor responses during hypothermia.", "content": "Preganglionic sympathetic activity and baroreceptor responses during hypothermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351831"}
{"pmid": "4351832", "title": "Postsynaptic potentials in the mesencephalic and pontomedullar reticular regions underlying descending limbic influences.", "content": "Postsynaptic potentials in the mesencephalic and pontomedullar reticular regions underlying descending limbic influences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351832"}
{"pmid": "4351833", "title": "Antagonistic effects of semicarbazide and pyridoxine on cuneate presynaptic inhibition.", "content": "Antagonistic effects of semicarbazide and pyridoxine on cuneate presynaptic inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351833"}
{"pmid": "4351835", "title": "Regional differences within the caudate nucleus for suppression of extralemniscal thalamic units.", "content": "Regional differences within the caudate nucleus for suppression of extralemniscal thalamic units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351835"}
{"pmid": "4351834", "title": "Effect of potassium ions on glucose and phospholipid metabolism in the rat's cervical sympathetic ganglia with and without axotomy.", "content": "Effect of potassium ions on glucose and phospholipid metabolism in the rat's cervical sympathetic ganglia with and without axotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351834"}
{"pmid": "4351836", "title": "Spontaneous bioelectric activity in long term cultures of the embryonic insect central nervous system.", "content": "Spontaneous bioelectric activity in long term cultures of the embryonic insect central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351836"}
{"pmid": "4351837", "title": "A nucleoside diphosphate phosphohydrolase present in a coated-vesicle fraction from synaptosomes of guinea-pig whole brain.", "content": "A nucleoside diphosphate phosphohydrolase present in a coated-vesicle fraction from synaptosomes of guinea-pig whole brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351837"}
{"pmid": "4351843", "title": "Syncardial massage in diabetic and other neuropathies of lower extremities.", "content": "Syncardial massage in diabetic and other neuropathies of lower extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351843"}
{"pmid": "4351846", "title": "The kinetics of the anaerobic reduction of fungal laccase B.", "content": "The kinetics of the anaerobic reduction of fungal laccase B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351846"}
{"pmid": "4351847", "title": "Specificity of aeromonas aminopeptidase toward oligopeptides and polypeptides.", "content": "Specificity of aeromonas aminopeptidase toward oligopeptides and polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351847"}
{"pmid": "4351848", "title": "Assay of yeast enzymes in situ. A potential tool in regulation studies.", "content": "Assay of yeast enzymes in situ. A potential tool in regulation studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351848"}
{"pmid": "4351849", "title": "The inhibitory effect of AMP on the activation reactions of the amino acids involved in gramicidin S biosynthesis.", "content": "The inhibitory effect of AMP on the activation reactions of the amino acids involved in gramicidin S biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351849"}
{"pmid": "4351850", "title": "Enzymes of Bacillus licheniformis in the biosynthesis of Bacitracin A.", "content": "Enzymes of Bacillus licheniformis in the biosynthesis of Bacitracin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351850"}
{"pmid": "4351852", "title": "Selective cleavage of the single tryptophanyl peptide bond in horse heart cytochrome c.", "content": "Selective cleavage of the single tryptophanyl peptide bond in horse heart cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351852"}
{"pmid": "4351851", "title": "Reaction of sulfenyl halides with cytochrome c. A novel method for heme cleavage.", "content": "Reaction of sulfenyl halides with cytochrome c. A novel method for heme cleavage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351851"}
{"pmid": "4351853", "title": "An intermediate in the reaction of reduced laccase with oxygen.", "content": "An intermediate in the reaction of reduced laccase with oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351853"}
{"pmid": "4351854", "title": "Cytoplasmic DNA's consisting of unique nuclear sequences in hamster cells. A possible role in cell differentiation and oncogenesis.", "content": "Cytoplasmic DNA's consisting of unique nuclear sequences in hamster cells. A possible role in cell differentiation and oncogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351854"}
{"pmid": "4351855", "title": "Glycolipid synthesis in baby-hamster-kidney fibroblasts transformed by a thermosensitive mutant of polyoma virus.", "content": "Glycolipid synthesis in baby-hamster-kidney fibroblasts transformed by a thermosensitive mutant of polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351855"}
{"pmid": "4351856", "title": "Effects of hormones on cyclic AMP release in perfused rat livers.", "content": "Effects of hormones on cyclic AMP release in perfused rat livers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351856"}
{"pmid": "4351858", "title": "In vitro studies on the acylation of 1-O-alkenyl glycero-3-phosphorylethanolamine by rat brain preparations.", "content": "In vitro studies on the acylation of 1-O-alkenyl glycero-3-phosphorylethanolamine by rat brain preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351858"}
{"pmid": "4351857", "title": "Evidence for an insulin receptor in muscle.", "content": "Evidence for an insulin receptor in muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351857"}
{"pmid": "4351863", "title": "The proton relaxation enhancement properties of concanavalin A.", "content": "The proton relaxation enhancement properties of concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351863"}
{"pmid": "4351864", "title": "Characterization of the specific androgen receptors in the human prostate gland.", "content": "Characterization of the specific androgen receptors in the human prostate gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351864"}
{"pmid": "4351866", "title": "Effect of perphenazine during late pregnancy on prolactin production and lactogenesis in the rat.", "content": "Effect of perphenazine during late pregnancy on prolactin production and lactogenesis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351866"}
{"pmid": "4351865", "title": "Effect of stress and environmental temperature on adrenal function in Rana esculenta.", "content": "Effect of stress and environmental temperature on adrenal function in Rana esculenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351865"}
{"pmid": "4351867", "title": "Effect of human chorionic gonadotrophin on testicular 5 -adnrostane-3 -hydroxysteroid dehydrogenase, 3 -hydroxydehydroepiandrosterone dehydrogenase and alcohol dehydrogenase of immature rats.", "content": "Effect of human chorionic gonadotrophin on testicular 5 -adnrostane-3 -hydroxysteroid dehydrogenase, 3 -hydroxydehydroepiandrosterone dehydrogenase and alcohol dehydrogenase of immature rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351867"}
{"pmid": "4351868", "title": "Further studies on the trophic effect of cyclic GMP on rat adrenal cortex.", "content": "Further studies on the trophic effect of cyclic GMP on rat adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351868"}
{"pmid": "4351869", "title": "Intrarenal teratoma occurring in infancy: report of a case with discussion of extragonodal germ cell tumors in infancy.", "content": "Intrarenal teratoma occurring in infancy: report of a case with discussion of extragonodal germ cell tumors in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351869"}
{"pmid": "4351860", "title": "The impacts of NIMH grants to improve state hospitals.", "content": "The impacts of NIMH grants to improve state hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351860"}
{"pmid": "4351871", "title": "Isolation and identification of trachoma and inclusion conjunctivitis agents in Melbourne, 1966 to 1972.", "content": "Isolation and identification of trachoma and inclusion conjunctivitis agents in Melbourne, 1966 to 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351871"}
{"pmid": "4351870", "title": "Gas gangrene--a ten-year survey from the Royal Adelaide Hospital.", "content": "Gas gangrene--a ten-year survey from the Royal Adelaide Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351870"}
{"pmid": "4351861", "title": "The influence of state regulatory processes on mental health programs.", "content": "The influence of state regulatory processes on mental health programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351861"}
{"pmid": "4351859", "title": "Implications of psychological research for smoking control clinics.", "content": "Implications of psychological research for smoking control clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351859"}
{"pmid": "4351874", "title": "Treatment of testicular tumors.", "content": "Treatment of testicular tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351874"}
{"pmid": "4351875", "title": "Mesodermal mixed tumor of the corpus uteri.", "content": "Mesodermal mixed tumor of the corpus uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351875"}
{"pmid": "4351880", "title": "ECS produced disruption or facilitation of discriminated active avoidance performance in rats.", "content": "ECS produced disruption or facilitation of discriminated active avoidance performance in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351880"}
{"pmid": "4351884", "title": "Estrogen-binding to pancreas.", "content": "Estrogen-binding to pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351884"}
{"pmid": "4351889", "title": "Trypsin aerosol treatment of pulmonary alveolar proteinosis. Case report.", "content": "Trypsin aerosol treatment of pulmonary alveolar proteinosis. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351889"}
{"pmid": "4351888", "title": "Studies on uterine flushings in the baboon. II. The effect of an intrauterine contraceptive device on certain biochemical parameters.", "content": "Studies on uterine flushings in the baboon. II. The effect of an intrauterine contraceptive device on certain biochemical parameters. This paper reports on the concentration of total protein, reducing sugar, and various enzymes in uterine flushings obtained from 17 mature, regularly cyclic baboons and stored at -10 degrees C until required.  It was found that the levels of total protein and reducing sugar was high at both the early proliferative and late secretory stages of the menstru al cycle and fell to their lowest levels in the early secretory phase.  When an IUD was in situ, higher levels of these 2 constituents occurred.  Of the enzymes measured in the early secretory phase, only hemoglobinase was significantly elevated in the presence of an IUD.  Trypsin, chymotrypsin, lysozyme, amylase, and phosphatase were usually detectable in the flushes, but none was significantly altered by the device.  The possible biologic implications of these findings are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351888"}
{"pmid": "4351887", "title": "Modified hormonal control of enzymatic activity in tumors.", "content": "Modified hormonal control of enzymatic activity in tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351887"}
{"pmid": "4351901", "title": "Isoproterenol and glucagon effects in perfused hearts from spontaneously hypertensive and normotensive rats.", "content": "Isoproterenol and glucagon effects in perfused hearts from spontaneously hypertensive and normotensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351901"}
{"pmid": "4351900", "title": "Effect of sodium n-dipropylacetate on audiogenic seizures and brain  -aminobutyric acid level.", "content": "Effect of sodium n-dipropylacetate on audiogenic seizures and brain  -aminobutyric acid level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351900"}
{"pmid": "4351902", "title": "The uptake of (14 C) glucose into rabbit ear cartilage proteoglycans isolated by differential extraction and by collagenase digestion.", "content": "The uptake of (14 C) glucose into rabbit ear cartilage proteoglycans isolated by differential extraction and by collagenase digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351902"}
{"pmid": "4351906", "title": "The Hermansky-Pudlak syndrome: inclusions in circulating leucocytes.", "content": "The Hermansky-Pudlak syndrome: inclusions in circulating leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351906"}
{"pmid": "4351904", "title": "The biochemistry of ferritin.", "content": "The biochemistry of ferritin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351904"}
{"pmid": "4351905", "title": "A genetically determined disorder with features both of thalassaemia and congenital dyserythropoietic anaemia.", "content": "A genetically determined disorder with features both of thalassaemia and congenital dyserythropoietic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351905"}
{"pmid": "4351907", "title": "Hypophysis and function of pancreatic islets. II. The effect of substitution with growth hormone and corticotrophin on insulin secretion and biosynthesis of proinsulin and insulin in isolated pancreatic islets of hypophysectomized rats.", "content": "Hypophysis and function of pancreatic islets. II. The effect of substitution with growth hormone and corticotrophin on insulin secretion and biosynthesis of proinsulin and insulin in isolated pancreatic islets of hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351907"}
{"pmid": "4351909", "title": "Toxicology's need for new analytical methods.", "content": "Toxicology's need for new analytical methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351909"}
{"pmid": "4351910", "title": "Distribution and localization of sites of gamma aminobutyric acid metabolism in the adult rat brain.", "content": "Distribution and localization of sites of gamma aminobutyric acid metabolism in the adult rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351910"}
{"pmid": "4351911", "title": "A radiographic study of the growth of the rat pelvis.", "content": "A radiographic study of the growth of the rat pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351911"}
{"pmid": "4351914", "title": "Synthesis and biological effects of 13-dehydro derivatives of natural prostaglandin F 2   and E 2  and their l5-epi enantiomers.", "content": "Synthesis and biological effects of 13-dehydro derivatives of natural prostaglandin F 2   and E 2  and their l5-epi enantiomers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351914"}
{"pmid": "4351912", "title": "Antiparasitic nitroimidazoles. 3. Synthesis of 2-(4-carboxystyryl)-5-nitro-1-vinylimidazole and related compounds.", "content": "Antiparasitic nitroimidazoles. 3. Synthesis of 2-(4-carboxystyryl)-5-nitro-1-vinylimidazole and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351912"}
{"pmid": "4351913", "title": "Synthesis and biological evaluation of LH and FSH releasing hormone and its analogs.", "content": "Synthesis and biological evaluation of LH and FSH releasing hormone and its analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351913"}
{"pmid": "4351916", "title": "The effects of corticosterone, 18-OH-DOC, DOC and 11 -hydroxyprogesterone on the adrenal pituitary axis of the stressed rat.", "content": "The effects of corticosterone, 18-OH-DOC, DOC and 11 -hydroxyprogesterone on the adrenal pituitary axis of the stressed rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351916"}
{"pmid": "4351915", "title": "Influence of protein under- and overnutrition on spontaneous tumor prevalence in the rat.", "content": "Influence of protein under- and overnutrition on spontaneous tumor prevalence in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351915"}
{"pmid": "4351917", "title": "In vivo and in vitro testosterone metabolism by the androgen insensitive rat.", "content": "In vivo and in vitro testosterone metabolism by the androgen insensitive rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351917"}
{"pmid": "4351919", "title": "Gas chromatographic determination and mass spectrometric identification of oestrogens in normal human placental tissue at term.", "content": "Gas chromatographic determination and mass spectrometric identification of oestrogens in normal human placental tissue at term.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351919"}
{"pmid": "4351918", "title": "Differences between rats and chickens in response to synthetic glucocorticosteroid.", "content": "Differences between rats and chickens in response to synthetic glucocorticosteroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351918"}
{"pmid": "4351921", "title": "Tumours of the glomus jugulare.", "content": "Tumours of the glomus jugulare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351921"}
{"pmid": "4351920", "title": "Metabolism of ( 3 H)-testosterone by the adrenal of the dog: the action of ACTH.", "content": "Metabolism of ( 3 H)-testosterone by the adrenal of the dog: the action of ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351920"}
{"pmid": "4351925", "title": "Right-sided abscess in the region of the diaphragm associated with bronchiectasis.", "content": "Right-sided abscess in the region of the diaphragm associated with bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351925"}
{"pmid": "4351924", "title": "Hydrocortisone and vascular reactivity in dogs with hemorrhagic shock.", "content": "Hydrocortisone and vascular reactivity in dogs with hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351924"}
{"pmid": "4351926", "title": "Humoral factors influencing cell-mediated immune responses to tumour-associated antigens.", "content": "Humoral factors influencing cell-mediated immune responses to tumour-associated antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351926"}
{"pmid": "4351933", "title": "Descending pathways in the spinal cord affecting sympathetic activity in spinalized cats.", "content": "Descending pathways in the spinal cord affecting sympathetic activity in spinalized cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351933"}
{"pmid": "4351934", "title": "The problem of \"sympathetic tone\" with particular respect to sleep.", "content": "The problem of \"sympathetic tone\" with particular respect to sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351934"}
{"pmid": "4351943", "title": "Optimization aspects in biological control theory.", "content": "Optimization aspects in biological control theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351943"}
{"pmid": "4351944", "title": "A rapid electrophoretic technique for identification of subunit species of apoproteins in serum lipoproteins.", "content": "A rapid electrophoretic technique for identification of subunit species of apoproteins in serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351944"}
{"pmid": "4351945", "title": "Atomic absorption determination of zinc, copper, cadmium, and lead in tissues solubilized by aqueous tetramethylammonium hydroxide.", "content": "Atomic absorption determination of zinc, copper, cadmium, and lead in tissues solubilized by aqueous tetramethylammonium hydroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351945"}
{"pmid": "4351946", "title": "Alternative methods of preparation and analysis of quasicrystalline protein from Neurospora crassa.", "content": "Alternative methods of preparation and analysis of quasicrystalline protein from Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351946"}
{"pmid": "4351935", "title": "Mathematical model of the neuron used for analysis of periodically modulated patterns of discharges.", "content": "Mathematical model of the neuron used for analysis of periodically modulated patterns of discharges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351935"}
{"pmid": "4351947", "title": "Preparation of protohemin monomethyl ester.", "content": "Preparation of protohemin monomethyl ester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351947"}
{"pmid": "4351948", "title": "An improved cycling assay for nicotinamide adenine dinucleotide.", "content": "An improved cycling assay for nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351948"}
{"pmid": "4351949", "title": "A new electrophoretic-autoradiographic method for the visual detection of phosphotransferases.", "content": "A new electrophoretic-autoradiographic method for the visual detection of phosphotransferases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351949"}
{"pmid": "4351936", "title": "The changes of noradrenaline in sympathetic ganglia and in the brain under reflex and humoral influences.", "content": "The changes of noradrenaline in sympathetic ganglia and in the brain under reflex and humoral influences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351936"}
{"pmid": "4351950", "title": "A note on the functional significance of phosphatases in the club cells of a fresh-water teleost, Saccobranchus fossilis.", "content": "A note on the functional significance of phosphatases in the club cells of a fresh-water teleost, Saccobranchus fossilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351950"}
{"pmid": "4351938", "title": "Muscarinic inhibition of the release of the adrenergic transmitter from peripheral sympathetic fibres.", "content": "Muscarinic inhibition of the release of the adrenergic transmitter from peripheral sympathetic fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351938"}
{"pmid": "4351937", "title": "Quantitative aspects of the release of noradrenaline from peripheral adrenergic neurones.", "content": "Quantitative aspects of the release of noradrenaline from peripheral adrenergic neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351937"}
{"pmid": "4351941", "title": "Frequency response analysis of inotropic nerve action upon the isolated sympathetically innervated guinea-pig atrium.", "content": "Frequency response analysis of inotropic nerve action upon the isolated sympathetically innervated guinea-pig atrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351941"}
{"pmid": "4351951", "title": "Inhibition of ACTH-induced differentiation of cortical cells and their mitochondria by corticosterone in tissue culture of fetal rat adrenals.", "content": "Inhibition of ACTH-induced differentiation of cortical cells and their mitochondria by corticosterone in tissue culture of fetal rat adrenals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351951"}
{"pmid": "4351940", "title": "Morpho-physiological consideration on synaptic transmission in the amphibian sympathetic ganglion.", "content": "Morpho-physiological consideration on synaptic transmission in the amphibian sympathetic ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351940"}
{"pmid": "4351952", "title": "Ablation therapy for hormone-dependent tumors.", "content": "Ablation therapy for hormone-dependent tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351952"}
{"pmid": "4351939", "title": "Importance of axonal transport of new amine granules for  3 H-noradrenaline retention capacity of adrenergic nerve terminals.", "content": "Importance of axonal transport of new amine granules for  3 H-noradrenaline retention capacity of adrenergic nerve terminals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351939"}
{"pmid": "4351942", "title": "A possible role of the catecholamine-containing neurons of the brain-stem of the cat in the sleep-waking cycle.", "content": "A possible role of the catecholamine-containing neurons of the brain-stem of the cat in the sleep-waking cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351942"}
{"pmid": "4351959", "title": "The utilization of zwitterionic buffer system in the plaque assay of a feline calicivirus.", "content": "The utilization of zwitterionic buffer system in the plaque assay of a feline calicivirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351959"}
{"pmid": "4351954", "title": "The reaction of products of sequential periodate oxidation of human erythrocyte glycoproteins with hemagglutinin from Helix pomatia.", "content": "The reaction of products of sequential periodate oxidation of human erythrocyte glycoproteins with hemagglutinin from Helix pomatia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351954"}
{"pmid": "4351955", "title": "Femoral neuropathy due to retroperitoneal bleeding. An unusual complication of heparin therapy.", "content": "Femoral neuropathy due to retroperitoneal bleeding. An unusual complication of heparin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351955"}
{"pmid": "4351953", "title": "Chemical mediation of hormone action.", "content": "Chemical mediation of hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351953"}
{"pmid": "4351960", "title": "The recognition of viruses of the avian leucosis-sarcoma group and other viruses that interfere with Marek's disease research.", "content": "The recognition of viruses of the avian leucosis-sarcoma group and other viruses that interfere with Marek's disease research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351960"}
{"pmid": "4351958", "title": "A review of arthropod-borne virus infections affecting man and animals in Australia.", "content": "A review of arthropod-borne virus infections affecting man and animals in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351958"}
{"pmid": "4351965", "title": "Analytical methods for mycotoxins.", "content": "Analytical methods for mycotoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351965"}
{"pmid": "4351966", "title": "Lesions of renal glomeruli in mice with virus-induced diabetes mellitus-like disease.", "content": "Lesions of renal glomeruli in mice with virus-induced diabetes mellitus-like disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351966"}
{"pmid": "4351968", "title": "A radioimmunoassay for alpha 1 -foetoprotein.", "content": "A radioimmunoassay for alpha 1 -foetoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351968"}
{"pmid": "4351967", "title": "Biochemical and morphological investigations of 30 human insulinomas. Correlation between the tumour content of insulin and proinsulin-like components and the histological and ultrastructural appearance.", "content": "Biochemical and morphological investigations of 30 human insulinomas. Correlation between the tumour content of insulin and proinsulin-like components and the histological and ultrastructural appearance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351967"}
{"pmid": "4351956", "title": "Articular chondrocalcinosis. Microanalysis of pyrophosphate (PPi) in synovial fluid and plasma.", "content": "Articular chondrocalcinosis. Microanalysis of pyrophosphate (PPi) in synovial fluid and plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351956"}
{"pmid": "4351969", "title": "Antigenic relationships among four herpesviruses.", "content": "Antigenic relationships among four herpesviruses. Common viral antigens were detected, by fluorescent-antibody studies, in cells infected with herpes simplex virus 1, squirrel monkey herpesvirus 1, bovine rhinotracheitis, and equine abortion viruses. The two primate viruses showed slight cross-neutralization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351969"}
{"pmid": "4351970", "title": "Host defense mechanisms against Herpes simplex virus. I. Control of infection in vitro by senstized spleen cells and antibody.", "content": "Host defense mechanisms against Herpes simplex virus. I. Control of infection in vitro by senstized spleen cells and antibody. Sensitized mouse spleen cells decrease the spread of herpes simplex virus infection in cell culture lines derived from human and murine tissues. These washed, sensitized cells act alone and additively in combination with antibody to diminish the ability of single virus-infected cells to spread infection to contiguous cells. This control of infection is not species specific, unlike interferon, and appears to be distinct from the effect of antibody. Lymphotoxin was not detected in this lymphocyte-mediated response. This control of herpes simplex virus infection in vitro by sensitized lymphoid cells is immunologically specific; spleen cells from donor animals immunized with a heterotypic virus do not cause herpesvirus plaque size reduction. The ratio of spleen cells from immunized animals to target monolayer cells needed to produce this effect is > 4:1. Plaque size reduction of herpes simplex virus by spleen cells requires intact, immune, non-glass-adhering lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351970"}
{"pmid": "4351972", "title": "Leukocytosis-promoting factor of Bordetella pertussis. II. Biological properties.", "content": "Leukocytosis-promoting factor of Bordetella pertussis. II. Biological properties. The leukocytosis-promoting factor (LPF), purified from materials extracted from agar in which Bordetella pertussis was grown, caused leukocytosis and an increased sensitivity to histamine when as little as 0.04 mug of protein was given intravenously to mice. LPF was adsorbed onto erythrocytes, causing hemagglutination. As little as 0.03 mug of LPF protein agglutinated chicken erythrocytes in 0.05 ml of a 0.5% suspension. The physicochemical, biological, and immunological properties indicated that leukocytosis, increased sensitivity to histamine in mice, and agglutination of erythrocytes are functions of a single substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351972"}
{"pmid": "4351971", "title": "Isolation and characterization of an Avian adenovirus-associated virus.", "content": "Isolation and characterization of an Avian adenovirus-associated virus. An 18- to 20-nm virus particle was isolated from the Olson strain of quail bronchitis, an avian adenovirus. On density gradient separation the small virions were primarily found at densities of 1.39 and 1.42 g/cm(3). The majority of the infectious particles were at the heavier density. The virus had a hexagonal outline and contained single-stranded deoxyribonucleic acid. It was resistant to heating at 56 C for more than an hour and was not inactivated by treatment with chloroform or low pH. Purified virus did not agglutinate erythrocytes of various avian and mammalian species. Replication of the small particles occurred either in chicken embryos or in cultures of embryo kidney cells coinfected with an adenovirus helper. Antigenically the virus was distinct from the adeno-associated viruses types 1, 2, 3, and 4. The virus is the avian equivalent of the adeno-associated viruses of primates and lower animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351971"}
{"pmid": "4351957", "title": "Experimental viral arthritis induced with herpes simplex.", "content": "Experimental viral arthritis induced with herpes simplex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351957"}
{"pmid": "4351974", "title": "Cytomegalovirus infections during acute childhood leukemia.", "content": "Cytomegalovirus infections during acute childhood leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351974"}
{"pmid": "4351973", "title": "Antimetabolites of coenzyme Q. XV. Inhibition of mitochondrial reductase systems by naphthoquinone and quinolinequinone analogs.", "content": "Antimetabolites of coenzyme Q. XV. Inhibition of mitochondrial reductase systems by naphthoquinone and quinolinequinone analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351973"}
{"pmid": "4351975", "title": "Isolation and comparison of bovine parvoviruses.", "content": "Isolation and comparison of bovine parvoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351975"}
{"pmid": "4351976", "title": "Responses of gibbons to inoculation of Epstein-Barr virus.", "content": "Responses of gibbons to inoculation of Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351976"}
{"pmid": "4351977", "title": "Dynamics of the splenic erythrocyte reservoir in the dog.", "content": "Dynamics of the splenic erythrocyte reservoir in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351977"}
{"pmid": "4351979", "title": "Activation and inhibition of blood platelet adenylate cyclase by adenosine or by 2-chloroadenosine.", "content": "Activation and inhibition of blood platelet adenylate cyclase by adenosine or by 2-chloroadenosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351979"}
{"pmid": "4351980", "title": "Diet in the prevention of heart disease.", "content": "Diet in the prevention of heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351980"}
{"pmid": "4351978", "title": "The in vitro sensitivity of fish brain ATPases to organochlorine acaricides.", "content": "The in vitro sensitivity of fish brain ATPases to organochlorine acaricides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351978"}
{"pmid": "4351981", "title": "Rhinoviruses.", "content": "Rhinoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351981"}
{"pmid": "4351984", "title": "Specificity of the control of protein synthesis by haemin.", "content": "Specificity of the control of protein synthesis by haemin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351984"}
{"pmid": "4351985", "title": "Comparison of free and 80S RNA-associated RNAs of mouse L cell virions.", "content": "Comparison of free and 80S RNA-associated RNAs of mouse L cell virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351985"}
{"pmid": "4351986", "title": "Influence of dibutyryl cyclicAMP and theophylline on cell surface antigens on oncornavirus transformed cells.", "content": "Influence of dibutyryl cyclicAMP and theophylline on cell surface antigens on oncornavirus transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351986"}
{"pmid": "4351987", "title": "Induction of steroidogenesis in tissue culture by cholera enterotoxin.", "content": "Induction of steroidogenesis in tissue culture by cholera enterotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351987"}
{"pmid": "4351988", "title": "Adrenergic receptors of the heart.", "content": "Adrenergic receptors of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351988"}
{"pmid": "4351989", "title": "Molecular mechanisms of hormone receptors.", "content": "Molecular mechanisms of hormone receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351989"}
{"pmid": "4351990", "title": "Isolation and characterization of hormone receptors.", "content": "Isolation and characterization of hormone receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351990"}
{"pmid": "4351992", "title": "Reduced high affinity 5 -dihydrotestosterone receptor capacity in the ventral prostate of the aging rat.", "content": "Reduced high affinity 5 -dihydrotestosterone receptor capacity in the ventral prostate of the aging rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351992"}
{"pmid": "4351996", "title": "Polydactyly in American negroes and whites.", "content": "Polydactyly in American negroes and whites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351996"}
{"pmid": "4351998", "title": "Crisis, conversion, and cult formation: an examination of a common psychosocial sequence.", "content": "Crisis, conversion, and cult formation: an examination of a common psychosocial sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351998"}
{"pmid": "4351997", "title": "Follow-up of adolescents treated in a psychiatric hospital. I. A review of studies.", "content": "Follow-up of adolescents treated in a psychiatric hospital. I. A review of studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351997"}
{"pmid": "4351999", "title": "Criterion approach to patient care evaluation.", "content": "Criterion approach to patient care evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4351999"}
{"pmid": "4352000", "title": "Urinary cyclic AMP in periodic catatonia.", "content": "Urinary cyclic AMP in periodic catatonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352000"}
{"pmid": "4352001", "title": "Collaborative provision of aftercare services.", "content": "Collaborative provision of aftercare services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352001"}
{"pmid": "4352008", "title": "Evaluation of agar-gel double diffusion for the diagnosis of adenovirus infection.", "content": "Evaluation of agar-gel double diffusion for the diagnosis of adenovirus infection. Agar-gel double diffusion was compared to the Laboratory Branch complement fixation test. The efficacy of the agar-gel double diffusion test for the semiquantitation of group-specific adenovirus antibody and its usefulness as a serodiagnostic aid for the evaluation of adenovirus infection was determined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352008"}
{"pmid": "4352007", "title": "Device for automatic rapid harvest of roller culture supernatant fluid.", "content": "Device for automatic rapid harvest of roller culture supernatant fluid. A machine has been designed to remove and replace supernatant fluids automatically from roller culture bottles at frequent intervals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352007"}
{"pmid": "4352003", "title": "Role of the lung in angiotensin metabolism.", "content": "Role of the lung in angiotensin metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352003"}
{"pmid": "4352012", "title": "Bilateral effects of the afferent impulses from the masseteric muscle on the trigeminal motoneuron of the cat.", "content": "Bilateral effects of the afferent impulses from the masseteric muscle on the trigeminal motoneuron of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352012"}
{"pmid": "4352010", "title": "Intrawell absorption of antisera in a template thin-film gel diffusion method.", "content": "Intrawell absorption of antisera in a template thin-film gel diffusion method. This report describes a method for in situ absorption of antisera within the template wells used in thin-film microgel diffusion. The intrawell absorption of antisera offers several advantages over previously reported techniques for detecting the presence of given antigens in biological preparations. The procedure is time saving, antigens are conserved, optimum antigen-antibody ratios are easily determined, and tests of several different absorbing antigens can be made on a single plate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352010"}
{"pmid": "4352009", "title": "Gentamicin blood agar used as a general-purpose selective medium.", "content": "Gentamicin blood agar used as a general-purpose selective medium. The potential value of a blood agar medium containing a final concentration of 5.5 mug of gentamicin per ml was assessed in a diagnostic laboratory over an 8-week period. The medium gave increased isolation rates of beta-hemolytic streptococci, other streptococci, Bacteroides, clostridia, and yeasts. It also proved valuable in detecting gentamicin-resistant gram-negative bacilli when these were present in heavy mixed culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352009"}
{"pmid": "4352004", "title": "Hormone producing tumors of the lung.", "content": "Hormone producing tumors of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352004"}
{"pmid": "4352011", "title": "Changes in the acetylcholine content in the rat brain after lesions of the septum, fimbria and hippocampus.", "content": "Changes in the acetylcholine content in the rat brain after lesions of the septum, fimbria and hippocampus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352011"}
{"pmid": "4352013", "title": "Some observations on the pathway of the vestibular rapid transmission system.", "content": "Some observations on the pathway of the vestibular rapid transmission system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352013"}
{"pmid": "4352014", "title": "Uptake of ( 14 C)glutamate into dorsal and ventral roots of spinal nerves of the rat.", "content": "Uptake of ( 14 C)glutamate into dorsal and ventral roots of spinal nerves of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352014"}
{"pmid": "4352015", "title": "The effect of cyclic N-2-O-dibutyryl-adenosine-3',5'-monophosphate, adenosine triphosphate and butyrate on the body temperature of conscious cats.", "content": "The effect of cyclic N-2-O-dibutyryl-adenosine-3',5'-monophosphate, adenosine triphosphate and butyrate on the body temperature of conscious cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352015"}
{"pmid": "4352016", "title": "Origin and central pathways of crossed inhibitory effects of afferents from the masseteric muscle on the masseteric motoneuron of the cat.", "content": "Origin and central pathways of crossed inhibitory effects of afferents from the masseteric muscle on the masseteric motoneuron of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352016"}
{"pmid": "4352018", "title": "Ectopic production of human chorionic gonadotropin in Ugandan patients with hepatocellular carcinoma.", "content": "Ectopic production of human chorionic gonadotropin in Ugandan patients with hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352018"}
{"pmid": "4352005", "title": "Cytologic diagnosis of lung lesions by bronchial brushing.", "content": "Cytologic diagnosis of lung lesions by bronchial brushing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352005"}
{"pmid": "4352019", "title": "Adriamycin--an antitumor antibiotic in the treatment of neoplastic diseases.", "content": "Adriamycin--an antitumor antibiotic in the treatment of neoplastic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352019"}
{"pmid": "4352020", "title": "Dependence of human erythrocyte PRPP synthetase specific activity on concentration.", "content": "Dependence of human erythrocyte PRPP synthetase specific activity on concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352020"}
{"pmid": "4352021", "title": "Neurospora crassa pyruvate dehydrogenase: interconversion by phosphorylation and dephosphorylation.", "content": "Neurospora crassa pyruvate dehydrogenase: interconversion by phosphorylation and dephosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352021"}
{"pmid": "4352022", "title": "The interaction of yeast inorganic pyrophosphatase with bivalent cations and pyrophosphate.", "content": "The interaction of yeast inorganic pyrophosphatase with bivalent cations and pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352022"}
{"pmid": "4352023", "title": "Inhibition of cyclic 3',5'-nucleotide phosphodiesterase in bovine taste papillae by bitter taste stimuli.", "content": "Inhibition of cyclic 3',5'-nucleotide phosphodiesterase in bovine taste papillae by bitter taste stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352023"}
{"pmid": "4352024", "title": "In vitro synthesis rat serum lipoproteins and proteins by Morris hepatoma 7777.", "content": "In vitro synthesis rat serum lipoproteins and proteins by Morris hepatoma 7777.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352024"}
{"pmid": "4352025", "title": "In vitro synthesis of rat serum lipoproteins and proteins by Morris hepatoma 7777.", "content": "In vitro synthesis of rat serum lipoproteins and proteins by Morris hepatoma 7777.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352025"}
{"pmid": "4352026", "title": "Structure-activity studies of MSH-release-inhibiting hormone.", "content": "Structure-activity studies of MSH-release-inhibiting hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352026"}
{"pmid": "4352027", "title": "Biosynthesis of mannan in Saccharomyces cerevisiae, isolation of a lipid intermediate and its identification as a mannosyl-1-phosphoryl polyrenol.", "content": "Biosynthesis of mannan in Saccharomyces cerevisiae, isolation of a lipid intermediate and its identification as a mannosyl-1-phosphoryl polyrenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352027"}
{"pmid": "4352028", "title": "Some observations on the cofactor requirement for partially purified DNA ligase from Escherichia coli.", "content": "Some observations on the cofactor requirement for partially purified DNA ligase from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352028"}
{"pmid": "4352031", "title": "A histochemical study on some enzyme changes in the kidney, liver and brain after chronic mercury intoxication in the rat.", "content": "A histochemical study on some enzyme changes in the kidney, liver and brain after chronic mercury intoxication in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352031"}
{"pmid": "4352030", "title": "Antioxidants and carcinogenesis: butylated hydroxytoluene, but not diphenyl-p-phenylenediamine, inhibits cancer induction by N-2-fluorenylacetamide and by N-hydroxy-N-2-fluorenylacetamide in rats.", "content": "Antioxidants and carcinogenesis: butylated hydroxytoluene, but not diphenyl-p-phenylenediamine, inhibits cancer induction by N-2-fluorenylacetamide and by N-hydroxy-N-2-fluorenylacetamide in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352030"}
{"pmid": "4352032", "title": "An improved sulphur assay applied to a problem of isethionate metabolism in squid axon and other nerves.", "content": "An improved sulphur assay applied to a problem of isethionate metabolism in squid axon and other nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352032"}
{"pmid": "4352033", "title": "Cyclic AMP and phosphodiesterase in synaptic vesicles from mouse brain.", "content": "Cyclic AMP and phosphodiesterase in synaptic vesicles from mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352033"}
{"pmid": "4352034", "title": "Effect of growth hormone on glycogenesis in cerebral cortical slices.", "content": "Effect of growth hormone on glycogenesis in cerebral cortical slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352034"}
{"pmid": "4352037", "title": "Agarose-gel electrophoresis of soluble proteins from bronchial mucosa and bronchogenic carcinoma.", "content": "Agarose-gel electrophoresis of soluble proteins from bronchial mucosa and bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352037"}
{"pmid": "4352036", "title": "Intracellular cyclic adenosine 3', 5'-monophosphate and relaxing effects of isoprenaline and papaverine on smooth muscle of intestine.", "content": "Intracellular cyclic adenosine 3', 5'-monophosphate and relaxing effects of isoprenaline and papaverine on smooth muscle of intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352036"}
{"pmid": "4352039", "title": "Interferon induction by bluetongue virus and bluetongue virus ribonucleic acid.", "content": "Interferon induction by bluetongue virus and bluetongue virus ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352039"}
{"pmid": "4352038", "title": "Cells, intracells and schizogeny. 3. Formation of intracells in human amnion cells and SV40 virus-transformed mouse embryo cells cultured in vitro.", "content": "Cells, intracells and schizogeny. 3. Formation of intracells in human amnion cells and SV40 virus-transformed mouse embryo cells cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352038"}
{"pmid": "4352040", "title": "Clinical foot-and-mouth disease in the African buffalo (Syncerus caffer).", "content": "Clinical foot-and-mouth disease in the African buffalo (Syncerus caffer).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352040"}
{"pmid": "4352042", "title": "Marijuana and ethanol: effects on sleep.", "content": "Marijuana and ethanol: effects on sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352042"}
{"pmid": "4352041", "title": "Viruses and myocarditis.", "content": "Viruses and myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352041"}
{"pmid": "4352047", "title": "Endocrine studies during a 14-day continuous exposure to 5.2 per cent O 2  in N 2  at pressure equivalent to 100 FSW (4 ATA).", "content": "Endocrine studies during a 14-day continuous exposure to 5.2 per cent O 2  in N 2  at pressure equivalent to 100 FSW (4 ATA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352047"}
{"pmid": "4352049", "title": "Anaesthesia and toxicity of angiotensin and 5-hydroxytryptamine in rats.", "content": "Anaesthesia and toxicity of angiotensin and 5-hydroxytryptamine in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352049"}
{"pmid": "4352050", "title": "Rise in plasma angiotensin II and of blood pressure induced by 5-hydroxytryptamine in rats.", "content": "Rise in plasma angiotensin II and of blood pressure induced by 5-hydroxytryptamine in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352050"}
{"pmid": "4352055", "title": "Cuticlin: a noncollagen structural protein from Ascaris cuticle.", "content": "Cuticlin: a noncollagen structural protein from Ascaris cuticle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352055"}
{"pmid": "4352053", "title": "Cyclic AMP inhibition of reactions of glyceraldehyde 3-phosphate dehydrogenase.", "content": "Cyclic AMP inhibition of reactions of glyceraldehyde 3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352053"}
{"pmid": "4352054", "title": "Reaction of celite-bound fluorescein isothiocyanate with the 50S E. coli ribosomal subunit.", "content": "Reaction of celite-bound fluorescein isothiocyanate with the 50S E. coli ribosomal subunit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352054"}
{"pmid": "4352056", "title": "Modification by bovine growth hormone of liver plasma membrane enzymes, phospholipids, and circular dichroism.", "content": "Modification by bovine growth hormone of liver plasma membrane enzymes, phospholipids, and circular dichroism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352056"}
{"pmid": "4352057", "title": "Role of modifications in tyrosine transfer RNA. II. Ribothymidylate-deficient tRNA.", "content": "Role of modifications in tyrosine transfer RNA. II. Ribothymidylate-deficient tRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352057"}
{"pmid": "4352058", "title": "Studies of the copper and heme cofactors of pseudomonad L-tryptophan-2,3-dioxygenase by electron paramagnetic resonance spectroscopy.", "content": "Studies of the copper and heme cofactors of pseudomonad L-tryptophan-2,3-dioxygenase by electron paramagnetic resonance spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352058"}
{"pmid": "4352059", "title": "Studies on the properties of 1,N 6 -ethenoadenine derivatives of various coenzymes.", "content": "Studies on the properties of 1,N 6 -ethenoadenine derivatives of various coenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352059"}
{"pmid": "4352060", "title": "Virogenic properties of AKR mouse sarcoma cells induced by rous sarcoma virus.", "content": "Virogenic properties of AKR mouse sarcoma cells induced by rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352060"}
{"pmid": "4352062", "title": "Physicochemical studies of equine infectious anemia virus. V. Effect of ultraviolet irradiation on virus infectivity.", "content": "Physicochemical studies of equine infectious anemia virus. V. Effect of ultraviolet irradiation on virus infectivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352062"}
{"pmid": "4352061", "title": "Failure of actinomycin D to inhibit the induction of SV 40 viral antigen in BSC 1  transformed cells.", "content": "Failure of actinomycin D to inhibit the induction of SV 40 viral antigen in BSC 1  transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352061"}
{"pmid": "4352063", "title": "A new species of poliovirus top component.", "content": "A new species of poliovirus top component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352063"}
{"pmid": "4352065", "title": "Orthophosphate and amino acids as nutritional factors stimulating diethylaminoethyl-dextran-induced cell sensitization to transfection.", "content": "Orthophosphate and amino acids as nutritional factors stimulating diethylaminoethyl-dextran-induced cell sensitization to transfection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352065"}
{"pmid": "4352064", "title": "Avian sarcoma virus transformed hamster cells resistant to bromodeoxyuridine and deficient in thymidine kinase activity.", "content": "Avian sarcoma virus transformed hamster cells resistant to bromodeoxyuridine and deficient in thymidine kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352064"}
{"pmid": "4352066", "title": "Experiences from investigations of virus isolations from sewage over a two year period with special regard to polioviruses.", "content": "Experiences from investigations of virus isolations from sewage over a two year period with special regard to polioviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352066"}
{"pmid": "4352068", "title": "Lateral phase separations in binary mixtures of cholesterol and phospholipids.", "content": "Lateral phase separations in binary mixtures of cholesterol and phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352068"}
{"pmid": "4352067", "title": "Stimulation in vitro of prostatic ribonucleic acid polymerase by 5 -dihydrotestosterone-receptor complexes.", "content": "Stimulation in vitro of prostatic ribonucleic acid polymerase by 5 -dihydrotestosterone-receptor complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352067"}
{"pmid": "4352069", "title": "Phosphodiesterase activity and the potentiation by theophylline of adrenocorticotrophin stimulated steroidogenesis and adenosine 3',5'-monophosphate levels in isolated rat adrenal cells.", "content": "Phosphodiesterase activity and the potentiation by theophylline of adrenocorticotrophin stimulated steroidogenesis and adenosine 3',5'-monophosphate levels in isolated rat adrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352069"}
{"pmid": "4352071", "title": "Phosphorylcholine: a specific promoter of reparin and serum  -lipoprotein interaction.", "content": "Phosphorylcholine: a specific promoter of reparin and serum  -lipoprotein interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352071"}
{"pmid": "4352070", "title": "Activation of the template activity of isolated rat liver nuclei for DNA synthesis and its inhibition by NAD.", "content": "Activation of the template activity of isolated rat liver nuclei for DNA synthesis and its inhibition by NAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352070"}
{"pmid": "4352072", "title": "A spin label study of E. coli membrane vesicles.", "content": "A spin label study of E. coli membrane vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352072"}
{"pmid": "4352073", "title": "The sequence and optical configuration of the amino acids xentoxin.", "content": "The sequence and optical configuration of the amino acids xentoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352073"}
{"pmid": "4352074", "title": "Allosteric and isosteric modifiers of NADH binding to cytoplasmic malic dehydrogenase.", "content": "Allosteric and isosteric modifiers of NADH binding to cytoplasmic malic dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352074"}
{"pmid": "4352075", "title": "Electrostatic interactions in the binding of fluorescent probes to lipid membranes.", "content": "Electrostatic interactions in the binding of fluorescent probes to lipid membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352075"}
{"pmid": "4352076", "title": "Phospholipid hydrolysis by phospholipase A 1  and A 2  in plasma membranes and microsomes of rat liver.", "content": "Phospholipid hydrolysis by phospholipase A 1  and A 2  in plasma membranes and microsomes of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352076"}
{"pmid": "4352077", "title": "Isolation and properties of skeletal muscle plasma membrane.", "content": "Isolation and properties of skeletal muscle plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352077"}
{"pmid": "4352078", "title": "Proteins and glycoproteins in plasma membrane fractions of avian leukosis-sarcoma virus susceptible and resistant chicken embryo fibroblasts.", "content": "Proteins and glycoproteins in plasma membrane fractions of avian leukosis-sarcoma virus susceptible and resistant chicken embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352078"}
{"pmid": "4352079", "title": "Structural properties of the membrane of intact human spermatozoa. A study with fluorescent probes.", "content": "Structural properties of the membrane of intact human spermatozoa. A study with fluorescent probes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352079"}
{"pmid": "4352080", "title": "The use of a PMR probe for studying the hydrophobic properties of Micrococcus lysodeikticus membranes and membrane fractions.", "content": "The use of a PMR probe for studying the hydrophobic properties of Micrococcus lysodeikticus membranes and membrane fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352080"}
{"pmid": "4352081", "title": "Ouabain binding sites and the (Na + ,K + )-ATPase of brain microsomal membranes.", "content": "Ouabain binding sites and the (Na + ,K + )-ATPase of brain microsomal membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352081"}
{"pmid": "4352082", "title": "Heart rate variability during sleep and wakefulness in low-birthweight infants.", "content": "Heart rate variability during sleep and wakefulness in low-birthweight infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352082"}
{"pmid": "4352083", "title": "The prejunctional actions of some non-depolarizing blocking drugs.", "content": "The prejunctional actions of some non-depolarizing blocking drugs. 1. Trains of end-plate potentials (e.p.p.s) have been recorded from the isolated tenuissimus of the cat. The muscle was paralyzed either by transversely cutting the muscle fibres or by non-depolarizing blocking drugs.2. The following parameters of transmitter synthesis, storage and release have been calculated: the quantal content of the first e.p.p. in the train, the size of the available store, fractional release, quantum size, and the rate of refilling of the available store.3. Tubocurarine and benzoquinonium depressed the rate of refilling of the available store causing its depletion at high rates of stimulation. This was offset by an increase in fractional release, which in the case of tubocurarine was sufficient for the quantal content of the first e.p.p. to be unchanged.4. Dimethyltubocurarine and pancuronium had a similar effect to tubocurarine on the rate of refilling of the store and depletion of the store at high rates of stimulation but did not increase fractional release. There was, therefore, a decrease in the quantal content of the first e.p.p.5. Lignocaine depressed the rate of refilling of the store and depleted the store at high rates of stimulation. Fractional release was also depressed.6. It is suggested that the non-depolarizing drugs have a weak local anaesthetic action retarding the influx of sodium into the nerve terminal which slows the rate of refilling of the store. This effect is due to the quaternary ammonium head. The presence of a phenolic group increases fractional release due either to an increased influx of calcium into the nerve terminal or to a potentiation of the actions of calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352083"}
{"pmid": "4352084", "title": "Some pharmacological effects of the nematocide, morantel.", "content": "Some pharmacological effects of the nematocide, morantel. 1. In isolated nerve-muscle preparations as well as in nerve-muscle preparations in intact anaesthetized animals, morantel exhibited neuromuscular blocking properties similar to those of depolarizing blockers. The drug also caused spastic paralysis of 3 day-old chicks and contracture of the isolated toad rectus abdominis muscle.2. Morantel caused contraction of the guinea-pig and rabbit isolated small intestine. This effect was antagonized by atropine and hexamethonium.3. Morantel caused an increase in the blood pressure of the anaesthetized rat and cat and contraction of the nictitating membrane of the anaesthetized cat. These effects were antagonized by hexamethonium.4. It was concluded that morantel (like the related compound pyrantel) has acetylcholine-like action and that its structure is consistent with such action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352084"}
{"pmid": "4352085", "title": "Effects of an isolated toxin from Australian tiger snake (Notechis scutatus scutatus) venom at the mammalian neuromuscular junction.", "content": "Effects of an isolated toxin from Australian tiger snake (Notechis scutatus scutatus) venom at the mammalian neuromuscular junction. 1. The acute effects of a purified toxin from Australian Tiger snake (Notechis scutatus scutatus) venom have been investigated at the mammalian neuromuscular junction.2. The toxin was injected into the tail vein of mice. Death was due to respiratory paralysis.3. The resting membrane potential, and action potential of muscle fibres in muscles from in vivo intoxicated animals were normal.4. The frequency of miniature end plate potentials (m.e.p.p.s) from intoxicated nerve-muscle preparations was reduced, although m.e.p.p. amplitude was unaltered.5. Nerve stimulation resulted in end plate potentials (e.p.p.s) of quantal amplitude; only rarely was the e.p.p. large enough to give rise to an action potential.6. High (20 mM) K(+) did not increase m.e.p.p. frequency in intoxicated preparations.7. The toxin was largely ineffective in vitro.8. The similarities and differences between this toxin, beta-bungarotoxin and botulinum toxin are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352085"}
{"pmid": "4352087", "title": "Some effects of inhibiting endogenous prostaglandin formation on the responses of the cat spleen.", "content": "Some effects of inhibiting endogenous prostaglandin formation on the responses of the cat spleen. 1. Cat isolated spleens release prostaglandins into the venous effluent in response to stimuli such as nerve stimulation, noradrenaline and angiotensin II.2. The release of prostaglandins is abolished by pre-treatment of the spleen with indomethacin (0.3-5 mug/ml).3. The capsular and vascular responses to the different stimuli are augmented after inhibition of prostaglandin release.4. The prevention of prostaglandin release, as well as the augmentation of vascular and capsular responses, are reversible after indomethacin treatment is stopped.5. The role of prostaglandins as modulators of the responses to several stimuli is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352087"}
{"pmid": "4352086", "title": "Pharmacological properties of centrally-administered agents which interfere with neurotransmitter function: a comparison with the central depressant effects of ouabain.", "content": "Pharmacological properties of centrally-administered agents which interfere with neurotransmitter function: a comparison with the central depressant effects of ouabain. 1. Centrally administered sodium diethyldithiocarbamate (DDC) produced hypothermia, central nervous depression and potentiation of the antinociceptive effect of morphine. These effects resemble those seen with centrally administered ouabain. Furthermore, the interactions of (+)-amphetamine, desmethylimipramine and nialamide with DDC and ouabain were similar.2. 6-Hydroxydopamine by the same route also produced central nervous depressant effects including hypothermia, decreased locomotor activity and catalepsy but not ptosis.3. Both ouabain and chlorpromazine produced similar effects on behaviour and body temperature including selective abolition of a conditioned avoidance response.4. Although centrally administered tetrabenazine produced ptosis, decreased locomotor activity and catalepsy, it had no significant effect on body temperature. However, the hypothermia produced by peripherally administered reserpine was reversed by centrally administered dibutyryl cyclic 3',5'-adenosine monophosphate.5. Centrally administered cocaine and desmethylimipramine produced no depressant effects but an increased excitability and responsiveness were apparent in both cases.6. Although the observed behavioural depression and hypothermia can occur independently both seem to involve an interference with dopaminergic systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352086"}
{"pmid": "4352089", "title": "The surgical management of primary hepatocellular carcinoma in Uganda.", "content": "The surgical management of primary hepatocellular carcinoma in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352089"}
{"pmid": "4352088", "title": "Renin-like activity of the rat submaxillary gland: characterization and the effect of several drugs and stimuli.", "content": "Renin-like activity of the rat submaxillary gland: characterization and the effect of several drugs and stimuli. 1. Renin-like activity was found in rat submaxillary glands.2. This activity was destroyed by boiling, was non-dialyzable and showed an optimum at approximately 50 degrees C.3. Renin-like activity in the submaxillary gland was not diminished 24 h after nephrectomy but was considerably reduced after ligature of the submaxillary duct.4. Renin-like activity in the submaxillary gland was reduced following food-deprivation, water-deprivation or hypovolemia.5. Renin-like activity in the rat submaxillary gland was increased after isoproterenol administration but not following pilocarpine.6. Renin-like activity in the rat submaxillary gland was increased considerably by administration of NaCl or KCl, as well as following adrenalectomy.7. Chlorothiazide and ouabain increased submaxillary renin-like activity but diazoxide did not affect this activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352088"}
{"pmid": "4352090", "title": "Effects of exercise, training, and diet on muscle citric acid cycle enzyme activity.", "content": "Effects of exercise, training, and diet on muscle citric acid cycle enzyme activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352090"}
{"pmid": "4352092", "title": "Dog kidney phospholipids and the question of renin inhibition.", "content": "Dog kidney phospholipids and the question of renin inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352092"}
{"pmid": "4352091", "title": "Activity and positional specificity of a rat plasma phospholipase on phosphatidylethanolamine.", "content": "Activity and positional specificity of a rat plasma phospholipase on phosphatidylethanolamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352091"}
{"pmid": "4352093", "title": "A spin-labelled fluorescent probe for membranes.", "content": "A spin-labelled fluorescent probe for membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352093"}
{"pmid": "4352095", "title": "Chromatin low molecular weight RNA components.", "content": "Chromatin low molecular weight RNA components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352095"}
{"pmid": "4352094", "title": "Interrelationship between serum  -lipoprotein and cholinesterase.", "content": "Interrelationship between serum  -lipoprotein and cholinesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352094"}
{"pmid": "4352096", "title": "Translational control of protein synthesis in rat anterior pituitary by N 6 -2'-O-dibutyryl adenosine 3',5'-monophosphate.", "content": "Translational control of protein synthesis in rat anterior pituitary by N 6 -2'-O-dibutyryl adenosine 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352096"}
{"pmid": "4352097", "title": "Tumor and plasma ACTH concentrations in patients with and without the ectopic ACTH syndrome.", "content": "Tumor and plasma ACTH concentrations in patients with and without the ectopic ACTH syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352097"}
{"pmid": "4352098", "title": "ACTH secretion by bronchial carcinoid tumours.", "content": "ACTH secretion by bronchial carcinoid tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352098"}
{"pmid": "4352099", "title": "Steroid 17,20-desmolase deficiency: a new cause of male pseudohermaphroditism.", "content": "Steroid 17,20-desmolase deficiency: a new cause of male pseudohermaphroditism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352099"}
{"pmid": "4352103", "title": "Herpes simplex encephalitis: a light and electron microscopic study in a fatal case.", "content": "Herpes simplex encephalitis: a light and electron microscopic study in a fatal case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352103"}
{"pmid": "4352104", "title": "Forefoot reconstruction. A case study.", "content": "Forefoot reconstruction. A case study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352104"}
{"pmid": "4352105", "title": "Autogenous immunity to endogenous RNA tumor virus. Radioimmune precipitation assay of mouse serum antibody levels.", "content": "Autogenous immunity to endogenous RNA tumor virus. Radioimmune precipitation assay of mouse serum antibody levels. The radioimmune precipitation assay using (3)H-labeled AKR leukemia virus was applied to the detection and quantitation of natural serum antibodies directed against endogenous murine leukemia virus (MuLV) envelope antigens B6C3F(1) and BALB/c mice, which have low natural incidences of leukemia and lymphoma, and AKR mice, which have a high incidence, were used in this study. Sera from mice of various age groups were assayed. A marked difference in age-associated levels of the autogenous immune response to endogenous murine leukemia virus was detected, and the quantitative differences among these strains were inversely related to the incidence of lymphoma. The radioimmune precipitation test as applied was 500 times more sensitive than virus neutralization. That the reactions we have observed are specific is suggested by several lines of evidence, including the nonreactivity of normal hamster and absorbed rat serum, the positive reaction of absorbed rat anti-AKR serum, the inhibition of precipitation of labeled virus by purified unlabeled virus, and isopycnic gradient analysis of the reactive products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352105"}
{"pmid": "4352106", "title": "Stress relaxation in rat skin after treatment with hormones.", "content": "Stress relaxation in rat skin after treatment with hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352106"}
{"pmid": "4352110", "title": "Carcinogenesis in tissue culture. 21. Changes in back-transplantability of the population of rat ascites hepatoma JTC-15 cells during a long-term of cultivation.", "content": "Carcinogenesis in tissue culture. 21. Changes in back-transplantability of the population of rat ascites hepatoma JTC-15 cells during a long-term of cultivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352110"}
{"pmid": "4352109", "title": "Descending and segmental inhibition of transmission through the spinocervical tract.", "content": "Descending and segmental inhibition of transmission through the spinocervical tract. 1. Micro-electrode recordings were made from axons of the spinocervical tract in unanaesthetized decerebrate-spinal cats.2. The effects of stimulation of (1) descending systems at the level of the upper cervical spinal cord and (2) hind limb cutaneous nerves, on discharges of spinocervical tract neurones were examined.3. Effects were obtained from bilateral spinal cord regions in the dorsolateral funiculi and the most medial and ventral parts of the ventral funiculi and also from the dorsal columns in the upper cervical region even though the columns had been transected at low thoracic and upper lumbar levels.4. Stimulation of either descending or segmental systems inhibited spontaneous and evoked responses. Facilitation was not seen. The inhibition had a time course of up to 250 msec, with maximal action at 20-40 msec and was greatest for polysynaptic responses or those evoked from the smaller myelinated cutaneous axons.5. It is suggested that the descending and segmental systems converge on to common inhibitory interneurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352109"}
{"pmid": "4352107", "title": "Influence of chronic neostigmine treatment on the number of acetylcholine receptors and the release of acetylcholine from the rat diaphragm.", "content": "Influence of chronic neostigmine treatment on the number of acetylcholine receptors and the release of acetylcholine from the rat diaphragm. 1. Rats were treated twice daily for 7 days with neostigmine and the diaphragm was isolated for study of its acetylcholine content, release upon nerve stimulation and the number of receptors in the end-plate.2. While the content of total acetylcholine was unchanged, the release of acetylcholine on stimulation with trains of 500 pulses at 100 Hz every 20 sec was reduced by about 50%. Five days after the end of neostigmine treatment the release of acetylcholine recovered to normal.3. The total number of acetylcholine receptors in the end-plate as measured from the binding of N, O-di[(3)H]acetyl alpha-bungarotoxin was reduced from 2.1 x 10(7) to 1.2 x 10(7) per end-plate.4. The above-mentioned changes are not due to acute pharmacological effects of neostigmine, nor to an immediate effect of cholinesterase inhibition but presumably due to chronic accumulation of acetylcholine at the neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352107"}
{"pmid": "4352108", "title": "Effects of proteolytic enzymes on function and structure of frog neuromuscular junctions.", "content": "Effects of proteolytic enzymes on function and structure of frog neuromuscular junctions. 1. Frog cutaneous pectoris nerve-muscle preparations were incubated with collagenase and protease and examined with electrophysiological and electron microscopic techniques.2. The physiological properties and intracellular ultrastructural appearance of individual muscle and nerve cells were not affected by the enzyme treatment. However, neuromuscular transmission and the morphology of the nerve-muscle junction were altered.3. Collagenase produced an irreversible loss of activity of end-plate cholinesterase and a partial loss of stainable ;synaptic cleft material'.4. Protease produced these changes and, in addition, the entire basement membrane was digested, which led to ;synaptic disjunction' of nerve terminals and muscle end-plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352108"}
{"pmid": "4352111", "title": "Nasopharyngeal carcinoma and Epstein-Barr virus. I. Factors related to the anti-VCA antibody.", "content": "Nasopharyngeal carcinoma and Epstein-Barr virus. I. Factors related to the anti-VCA antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352111"}
{"pmid": "4352112", "title": "Nasopharyngeal carcinoma and Epstein-Barr virus. II. Clinical course and the anti-VCA antibody.", "content": "Nasopharyngeal carcinoma and Epstein-Barr virus. II. Clinical course and the anti-VCA antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352112"}
{"pmid": "4352113", "title": "Clostridium perfringens exotoxins. I. Purification and properties of  -toxin.", "content": "Clostridium perfringens exotoxins. I. Purification and properties of  -toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352113"}
{"pmid": "4352120", "title": "Mode of action of hallucinogenic molecules.", "content": "Mode of action of hallucinogenic molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352120"}
{"pmid": "4352119", "title": "Adenyl cyclase of polymorphonuclear leukocytes.", "content": "Adenyl cyclase of polymorphonuclear leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352119"}
{"pmid": "4352121", "title": "Assignment of codons to arginine residues in vertebrate proteins.", "content": "Assignment of codons to arginine residues in vertebrate proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352121"}
{"pmid": "4352123", "title": "Effects of flow-stop on the metabolism of noradrenaline released by nerve stimulation in the perfused spleen.", "content": "Effects of flow-stop on the metabolism of noradrenaline released by nerve stimulation in the perfused spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352123"}
{"pmid": "4352124", "title": "Alterations produced by cortisol in the spontaneous activity and responsiveness to sensory stimuli of single cells in the tuberal hypothalamus of the rat.", "content": "Alterations produced by cortisol in the spontaneous activity and responsiveness to sensory stimuli of single cells in the tuberal hypothalamus of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352124"}
{"pmid": "4352122", "title": "Influence of cyclization and acyl substitution on the inotropic effects of adenine nucleotides.", "content": "Influence of cyclization and acyl substitution on the inotropic effects of adenine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352122"}
{"pmid": "4352125", "title": "Studies on the in vitro and the in vivo transcription of the bluetongue virus genome.", "content": "Studies on the in vitro and the in vivo transcription of the bluetongue virus genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352125"}
{"pmid": "4352126", "title": "Visualization of the extracapsid coat in certain bluetongue-type viruses.", "content": "Visualization of the extracapsid coat in certain bluetongue-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352126"}
{"pmid": "4352127", "title": "Phagocytic activity of peritoneal exudate cells from mice.", "content": "Phagocytic activity of peritoneal exudate cells from mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352127"}
{"pmid": "4352128", "title": "Therapeutic planning for patients with lung cancer.", "content": "Therapeutic planning for patients with lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352128"}
{"pmid": "4352129", "title": "Lung biopsy: transbronchoscopic, percutaneous, open.", "content": "Lung biopsy: transbronchoscopic, percutaneous, open.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352129"}
{"pmid": "4352130", "title": "Mediastinal tumors and cysts in the pediatric patient.", "content": "Mediastinal tumors and cysts in the pediatric patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352130"}
{"pmid": "4352131", "title": "Alveolar and tissue phospholipids of rat lung.", "content": "Alveolar and tissue phospholipids of rat lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352131"}
{"pmid": "4352132", "title": "Effects of changes in sodium balance and of experimental renal hypertension on plasma angiotensin I converting enzyme activity of rabbits.", "content": "Effects of changes in sodium balance and of experimental renal hypertension on plasma angiotensin I converting enzyme activity of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352132"}
{"pmid": "4352133", "title": "The disinfection of instruments and hands during outbreaks of epidemic keratoconjunctivitis.", "content": "The disinfection of instruments and hands during outbreaks of epidemic keratoconjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352133"}
{"pmid": "4352134", "title": "Treatment of adenovirus type 8 kerato-conjunctivitis.", "content": "Treatment of adenovirus type 8 kerato-conjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352134"}
{"pmid": "4352135", "title": "Pseudomalignant cutaneous amoebiasis in Uganda.", "content": "Pseudomalignant cutaneous amoebiasis in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352135"}
{"pmid": "4352137", "title": "Riboflavin carrier protein from egg yolk. Spectral and other properties observed upon binding of flavin to apoprotein.", "content": "Riboflavin carrier protein from egg yolk. Spectral and other properties observed upon binding of flavin to apoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352137"}
{"pmid": "4352139", "title": "The effects of nitrofuranfuradroxyl on the phosphatase enzymes in kidney and liver of rats.", "content": "The effects of nitrofuranfuradroxyl on the phosphatase enzymes in kidney and liver of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352139"}
{"pmid": "4352140", "title": "Complex conformations in mitochondrial DNA isolated from rat ascites hepatoma cells.", "content": "Complex conformations in mitochondrial DNA isolated from rat ascites hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352140"}
{"pmid": "4352141", "title": "Probable explanation for differential inhibition of hepatoma growth in liver upon carbohydrate deprivation.", "content": "Probable explanation for differential inhibition of hepatoma growth in liver upon carbohydrate deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352141"}
{"pmid": "4352142", "title": "Studies on urinary infections in diabetics. IV. Significant bacteriuria in pregnancy in relation to age of onset, duration of diabetes, angiopathy and urological symptoms.", "content": "Studies on urinary infections in diabetics. IV. Significant bacteriuria in pregnancy in relation to age of onset, duration of diabetes, angiopathy and urological symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352142"}
{"pmid": "4352144", "title": "Studies on arterial and renal venous plasma renin activity in hypertensive patients.", "content": "Studies on arterial and renal venous plasma renin activity in hypertensive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352144"}
{"pmid": "4352145", "title": "Lipoprotein lipase activity of human adipose tissue in health and in some diseases with hyperlipidemia as a common feature.", "content": "Lipoprotein lipase activity of human adipose tissue in health and in some diseases with hyperlipidemia as a common feature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352145"}
{"pmid": "4352146", "title": "Cell size and lipolysis by human subcutaneous adipose tissue.", "content": "Cell size and lipolysis by human subcutaneous adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352146"}
{"pmid": "4352147", "title": "Primary epithelial neoplasms of the lacrimal sac.", "content": "Primary epithelial neoplasms of the lacrimal sac.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352147"}
{"pmid": "4352151", "title": "Parenteral long-acting corticosteroids: effect on hypothalamic-pituitary-adrenal function.", "content": "Parenteral long-acting corticosteroids: effect on hypothalamic-pituitary-adrenal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352151"}
{"pmid": "4352152", "title": "A new short-acting antagonist of angiotensin II.", "content": "A new short-acting antagonist of angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352152"}
{"pmid": "4352154", "title": "Influence of vasoactive hormones on mammary arterial blood flow in lactating cows.", "content": "Influence of vasoactive hormones on mammary arterial blood flow in lactating cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352154"}
{"pmid": "4352153", "title": "Mechanism of acetylcholine release by drugs and its blockade.", "content": "Mechanism of acetylcholine release by drugs and its blockade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352153"}
{"pmid": "4352155", "title": "Effect of sulfur compounds on various sulfhydryl-dependent enzyme systems.", "content": "Effect of sulfur compounds on various sulfhydryl-dependent enzyme systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352155"}
{"pmid": "4352156", "title": "Interaction of lipids with acid-soluble bovine skin collagen.", "content": "Interaction of lipids with acid-soluble bovine skin collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352156"}
{"pmid": "4352148", "title": "A philosophy of relaxation. Eleventh annual Baxter-Travenol lecture.", "content": "A philosophy of relaxation. Eleventh annual Baxter-Travenol lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352148"}
{"pmid": "4352158", "title": "Analysis of human hypoxanthine-guanine phosphoribosyl transferase isozymes by isoelectric focusing in polyacrylamide gel.", "content": "Analysis of human hypoxanthine-guanine phosphoribosyl transferase isozymes by isoelectric focusing in polyacrylamide gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352158"}
{"pmid": "4352157", "title": "Neonatal diseases in dogs and cats.", "content": "Neonatal diseases in dogs and cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352157"}
{"pmid": "4352159", "title": "Chronic benign familial pemphigus. Induction of lesions by Herpesvirus hominis.", "content": "Chronic benign familial pemphigus. Induction of lesions by Herpesvirus hominis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352159"}
{"pmid": "4352160", "title": "Pulmonary cavitary lesion with productive cough.", "content": "Pulmonary cavitary lesion with productive cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352160"}
{"pmid": "4352161", "title": "Cervical chemodectoma with extensive pulmonary metastases.", "content": "Cervical chemodectoma with extensive pulmonary metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352161"}
{"pmid": "4352149", "title": "Do maternally administered neuromuscular blocking agents interfere with fetal neuromuscular transmission?", "content": "Do maternally administered neuromuscular blocking agents interfere with fetal neuromuscular transmission?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352149"}
{"pmid": "4352162", "title": "Delayed granuloma following bronchography.", "content": "Delayed granuloma following bronchography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352162"}
{"pmid": "4352164", "title": "Mediastinal xanthoma with familial hyperlipoproteinemia.", "content": "Mediastinal xanthoma with familial hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352164"}
{"pmid": "4352165", "title": "Clinical staging of primary lung cancer.", "content": "Clinical staging of primary lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352165"}
{"pmid": "4352163", "title": "Wilms tumor: diagnosis by thoracentesis.", "content": "Wilms tumor: diagnosis by thoracentesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352163"}
{"pmid": "4352166", "title": "The spectrum of diffuse pulmonary infiltration in malignant disease.", "content": "The spectrum of diffuse pulmonary infiltration in malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352166"}
{"pmid": "4352167", "title": "Clinical significance of hemodynamic findings in hypertension.", "content": "Clinical significance of hemodynamic findings in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352167"}
{"pmid": "4352168", "title": "ACTH and calcitonin secreting medullary carcinoma of the thyroid.", "content": "ACTH and calcitonin secreting medullary carcinoma of the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352168"}
{"pmid": "4352150", "title": "The effect of renal failure and hyperkalemia on the duration of pancuronium neuromuscular blockade in man.", "content": "The effect of renal failure and hyperkalemia on the duration of pancuronium neuromuscular blockade in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352150"}
{"pmid": "4352169", "title": "The effect of chlorpromazine on pituitary function.", "content": "The effect of chlorpromazine on pituitary function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352169"}
{"pmid": "4352171", "title": "A radioimmunoassay for MTV-antigens.", "content": "A radioimmunoassay for MTV-antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352171"}
{"pmid": "4352170", "title": "Hydrolytic enzymes of the hepatopancreas of the ascidian, Pyura stolonifera.", "content": "Hydrolytic enzymes of the hepatopancreas of the ascidian, Pyura stolonifera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352170"}
{"pmid": "4352172", "title": "Carcinoma associated with fistula in ano.", "content": "Carcinoma associated with fistula in ano.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352172"}
{"pmid": "4352173", "title": "Gas gangrene of the anterior abdominal wall.", "content": "Gas gangrene of the anterior abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352173"}
{"pmid": "4352174", "title": "Histidyl-transfer ribonucleic acid synthetase mutants requiring a high internal pool of histidine for growth.", "content": "Histidyl-transfer ribonucleic acid synthetase mutants requiring a high internal pool of histidine for growth. Mutants that require histidine due to an altered structural gene for the histidyl-transfer ribonucleic acid synthetase (hisS) have been isolated by a general selection for histidine-requiring strains in which the mutation producing histidine auxotrophy is unlinked to the histidine operon. One of the mutants has been shown to require an abnormally high internal histidine pool for growth owing to an altered synthetase that is unstable at low histidine concentrations. It is difficult to determine accurately the K(m) for histidine of the synthetase enzyme from the mutant because of the instability of the enzyme at limiting histidine concentrations; however, a histidine K(m) value has been estimated that is approximately 100 times higher than the histidine K(m) of the wild-type enzyme. For the mutant strains to achieve the high internal pool of histidine required for growth, all the systems that transport histidine from the growth medium must be functioning to capacity. Amino acids that interfere with histidine transport strongly inhibit the growth of the mutants. The mutants have been useful in providing a selective genetic marker for transductional mapping in the hisS region. The mutants are discussed as representative of a general class of curable mutants that have an altered enzyme with poor affinity for a substrate or coenzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352174"}
{"pmid": "4352175", "title": "Common enzymes of branched-chain amino acid catabolism in Pseudomonas putida.", "content": "Common enzymes of branched-chain amino acid catabolism in Pseudomonas putida. Two types of Pseudomonas putida PpG2 mutants which were unable to degrade branched-chain amino acids were isolated after mutagenesis and selection for ability to grow on succinate, but not valine, as a sole source of carbon. These isolates were characterized by growth on the three branched-chain amino acids (valine, isoleucine, and leucine), on the corresponding branched-chain keto acids (2-ketoisovalerate, 2-keto-3-methylvalerate, and 2-ketoisocaproate), and on other selected intermediates as carbon sources, and by their enzymatic composition. One group of mutants lost 2-ketoisovalerate-inducible branched-chain keto acid dehydrogenase that was active on all three keto acids. There was also a concomitant loss of ability to grow on all three branched-chain amino acids as well as on all three corresponding keto acids, but there was retention of ability to use subsequent intermediates in the catabolism of branched-chain amino acids. Another type of mutant showed a marked reduction in branched-chain amino acid transaminase activity and grew poorly at the expense of all three amino acids, but it utilized subsequent intermediates as carbon sources. Both the transaminase and branched-chain keto acid dehydrogenase mutants retained the ability to degrade camphor. These findings are consistent with the view that branched-chain amino acid transaminase and branched-chain keto acid dehydrogenase are common enzymes in the catabolism of valine, isoleucine, and leucine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352175"}
{"pmid": "4352176", "title": "Genetic and biochemical investigation of the Escherichia coli mutant hfl-1 which is lysogenized at high frequency by bacteriophage lambda.", "content": "Genetic and biochemical investigation of the Escherichia coli mutant hfl-1 which is lysogenized at high frequency by bacteriophage lambda. The Escherichia coli mutant hfl-1 is lysogenized at very high frequency by bacteriophage lambda. The normal requirement for the lambdacIII gene product in the establishment of repression is not observed in hfl-1 strains. These phenotypic characteristics are specified by a single locus at 82.5 min on the E. coli map in extremely close proximity to the purA gene, cotransduction frequencies ranging from 97 to 100% depending on the particular purA marker used. The lactose operon is shown to function normally in this strain, and there are also no demonstrable differences in ribonucleic acid polymerase activity or cyclic-adenosine monophosphate levels. Alterations in the cell envelope are indicated by a slight rifamycin resistance, which is reversible by pretreating the cells with ethylenediaminetetraacetic acid, and by a resistance to penicillin and a sensitivity to high concentrations of sodium dodecyl sulfate. It is not known whether this change in cell surface is the primary lesion, or a pleiotropic effect of some more basic metabolic shift.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352176"}
{"pmid": "4352178", "title": "Relationship of adenosine 3',5'-monophosphate to growth and metabolism of Tetrahymena pyriformis.", "content": "Relationship of adenosine 3',5'-monophosphate to growth and metabolism of Tetrahymena pyriformis. The concentration of adenosine 3',5'-monophosphate (cyclic AMP) and the activity of adenylate cyclase were determined for the first time in conjuncation with cyclic 3',5'-nucleotide phosphodiesterase (phosphodiesterase) during the growth cycle of Tetrahymena pyriformis. High levels of cyclic AMP observed during early exponential and late stationary phases were associated with elevated adenylate cyclase and decreased phosphodiesterase activities. Adenylate cyclase and cyclic AMP were decreased and phosphodiesterase was increased in cells grown in glucose-supplemented medium. In contrast to findings in mammalian liver, cyclic AMP was decreased during active gluconeogenesis in Tetrahymena. This suggests a different modulation of carbohydrate metabolism in the two species. The results illustrate that both the content of cyclic AMP and its action as a regulatory agent in Tetrahymena are uniquely suited to the metabolism of this organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352178"}
{"pmid": "4352179", "title": "Respiratory development in Saccharomyces cerevisiae grown at controlled oxygen tension.", "content": "Respiratory development in Saccharomyces cerevisiae grown at controlled oxygen tension. Saccharomyces cerevisiae was grown in batch culture over a wide range of oxygen concentrations, varying from the anaerobic condition to a maximal dissolved oxygen concentration of 3.5 muM. The development of cells was assayed by measuring amounts of the aerobic cytochromes aa(3), b, c, and c(1), the cellular content of unsaturated fatty acids and ergosterol, and the activity of respiratory enzyme complexes. The half-maximal levels of membrane-bound cytochromes aa(3), b, and c(1), were reached in cells grown in O(2) concentrations around 0.1 muM; this was similar to the oxygen concentration required for half-maximal levels of unsaturated fatty acid and sterol. However, the synthesis of ubiquinone and cytochrome c and the increase in fumarase activity were essentially linear functions of the dissolved oxygen concentration up to 3.5 muM oxygen. The synthesis of the succinate dehydrogenase, succinate cytochrome c reductase, and cytochrome c oxidase complexes showed different responses to changes in O(2) concentration in the growth medium. Cyanide-insensitive respiration and P(450) cytochrome content were maximal at 0.25 muM oxygen and declined in both more anaerobic and aerobic conditions. Cytochrome c peroxidase and catalase activities in cell-free homogenates were high in all but the most strictly anaerobic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352179"}
{"pmid": "4352177", "title": "Metabolism of the pyridine nucleotides involved in nicotinamide adenine dinucleotide biosynthesis by Clostridium butylicum.", "content": "Metabolism of the pyridine nucleotides involved in nicotinamide adenine dinucleotide biosynthesis by Clostridium butylicum. In order to elucidate the mechanism of the accumulation of considerable amounts of free nicotinic acid (NA) in the culture medium of Clostridium butylicum, this organism was investigated with regard to its ability to metabolize nicotinamide adenine dinucleotide (NAD) and its immediate biosynthetic precursors, nicotinic acid mononucleotide (NAMN) and nicotinic acid adenine dinucleotide (deamido-NAD). Cell-free extracts of C. butylicum were found to degrade NAMN and deamido-NAD to NA. NAMN, in the presence of adenosine triphosphate (ATP), was converted to deamido-NAD, but only at high concentrations of ATP (20 mM) was significant synthetic activity observed in competition with NAMN degradation. Degradation of both NAMN and deamido-NAD was activated by ATP at concentrations of 5 and 10 mm. Anaerobiosis markedly enhanced the degradation of the nucleotides. The data indicate that the synthesis of NAMN and deamido-NAD prevails over their degradation only in the presence of high concentrations of ATP. NAD was degraded to nicotinamide mononucleotide (NMN) by a pyrophosphatase. Phosphate markedly inhibited both the deamido-NAD and NAD pyrophosphatases. Under anaerobic conditions there was practically no further degradation of NMN to NA, whereas barely measurable amounts of NA were formed under aerobic conditions. All of these observations suggest that, under the given conditions of anaerobiosis and physiological phosphate concentrations, there is very little degradation of NAD to NMN and practically no degradation to NA by C. butylicum. Thus, NAD represents an insignificant source of the NA accumulated in the culture medium. The intermediates in the biosynthetic pathway (NAMN and deamido-NAD) have been shown to be the major source of the NA which is accumulated by C. butylicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352177"}
{"pmid": "4352181", "title": "Inhibition by fluoride ion of hormonal activation of fat cell adenylate cyclase.", "content": "Inhibition by fluoride ion of hormonal activation of fat cell adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352181"}
{"pmid": "4352183", "title": "Fractionation of the C-apoproteins from human plasma very low density lipoproteins.", "content": "Fractionation of the C-apoproteins from human plasma very low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352183"}
{"pmid": "4352182", "title": "An iron-containing superoxide dismutase from Escherichia coli.", "content": "An iron-containing superoxide dismutase from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352182"}
{"pmid": "4352184", "title": "Effects of ethanol and fat on the transport of reducing equivalents into rat liver mitochondria.", "content": "Effects of ethanol and fat on the transport of reducing equivalents into rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352184"}
{"pmid": "4352180", "title": "Structure-function unitization model of biological membranes.", "content": "Structure-function unitization model of biological membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352180"}
{"pmid": "4352186", "title": "Studies on the role of ribosomal proteins L 7  and L 12  in the in vitro synthesis of  -galactosidase.", "content": "Studies on the role of ribosomal proteins L 7  and L 12  in the in vitro synthesis of  -galactosidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352186"}
{"pmid": "4352185", "title": "Comparative biological chemistry of cobalt hemoglobin.", "content": "Comparative biological chemistry of cobalt hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352185"}
{"pmid": "4352187", "title": "Glucocorticoid receptors in lung. II. Specific binding of glucocorticoids to nuclear components of rabbit fetal lung.", "content": "Glucocorticoid receptors in lung. II. Specific binding of glucocorticoids to nuclear components of rabbit fetal lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352187"}
{"pmid": "4352189", "title": "Preparation and characterization of plasma membranes from bovine corpus luteum.", "content": "Preparation and characterization of plasma membranes from bovine corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352189"}
{"pmid": "4352188", "title": "Properties of the luteinizing hormone receptor of isolated bovine corpus luteum plasma membranes.", "content": "Properties of the luteinizing hormone receptor of isolated bovine corpus luteum plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352188"}
{"pmid": "4352191", "title": "Perifused fat cells. Effect of lipolytic agents.", "content": "Perifused fat cells. Effect of lipolytic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352191"}
{"pmid": "4352190", "title": "The plasma membrane of isolated fat cells. I. Identification of trypsin-sensitive membrane peptides by sodium dodecyl sulfate polyacrylamide gel electrophoresis.", "content": "The plasma membrane of isolated fat cells. I. Identification of trypsin-sensitive membrane peptides by sodium dodecyl sulfate polyacrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352190"}
{"pmid": "4352192", "title": "The distribution of carbohydrate groups in rat skin collagen.", "content": "The distribution of carbohydrate groups in rat skin collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352192"}
{"pmid": "4352194", "title": "The dynamic equilibrium of folding and unfolding of nuclease-T.", "content": "The dynamic equilibrium of folding and unfolding of nuclease-T.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352194"}
{"pmid": "4352193", "title": "Function of phosphorylated ribosomes. The activity of ribosomal subunits phosphorylated in vitro by protein kinase.", "content": "Function of phosphorylated ribosomes. The activity of ribosomal subunits phosphorylated in vitro by protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352193"}
{"pmid": "4352196", "title": "Glucagon stimulation of adenylate cyclase sulfhydryl reactivity. Evidence for hormone-induced conformational changes.", "content": "Glucagon stimulation of adenylate cyclase sulfhydryl reactivity. Evidence for hormone-induced conformational changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352196"}
{"pmid": "4352198", "title": "Modification of the rat's startle reaction by termination of antecedent acoustic signals.", "content": "Modification of the rat's startle reaction by termination of antecedent acoustic signals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352198"}
{"pmid": "4352195", "title": "Positional specificities of acyl coenzyme A: glycerophosphate and acyl coenzyme A: monoacylglycerophosphate acyltransferases in Escherichia coli.", "content": "Positional specificities of acyl coenzyme A: glycerophosphate and acyl coenzyme A: monoacylglycerophosphate acyltransferases in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352195"}
{"pmid": "4352197", "title": "The valence and spin state of iron in oxyhemoglobin as inferred from resonance Raman spectroscopy.", "content": "The valence and spin state of iron in oxyhemoglobin as inferred from resonance Raman spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352197"}
{"pmid": "4352199", "title": "Localization of phosphatase activity on the membranes of the mammalian sperm head.", "content": "Localization of phosphatase activity on the membranes of the mammalian sperm head.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352199"}
{"pmid": "4352200", "title": "Neuraminidase \"unmasking\" and failure of trypsin to \"unmask\"  -D-galactose-like sites on erythrocyte, lymphoma, and normal and virus-transformed fibroblast cell membranes.", "content": "Neuraminidase \"unmasking\" and failure of trypsin to \"unmask\"  -D-galactose-like sites on erythrocyte, lymphoma, and normal and virus-transformed fibroblast cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352200"}
{"pmid": "4352202", "title": "Distinctive cells similar to fetal hepatocytes associated with liver carcinogenesis by diethylnitrosamine. Electron microscopic study.", "content": "Distinctive cells similar to fetal hepatocytes associated with liver carcinogenesis by diethylnitrosamine. Electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352202"}
{"pmid": "4352201", "title": "Anaerobic glycolysis in spontaneous and transplanted liver tumors of mice.", "content": "Anaerobic glycolysis in spontaneous and transplanted liver tumors of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352201"}
{"pmid": "4352203", "title": "Unusually high incidence of spontaneous lymphomas in wild house mice.", "content": "Unusually high incidence of spontaneous lymphomas in wild house mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352203"}
{"pmid": "4352204", "title": "Types B and C RNA virus in breast tissue and milk of wild mice.", "content": "Types B and C RNA virus in breast tissue and milk of wild mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352204"}
{"pmid": "4352205", "title": "Infection of embryonic myogenic cells with murine sarcoma virus in vitro.", "content": "Infection of embryonic myogenic cells with murine sarcoma virus in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352205"}
{"pmid": "4352206", "title": "Immunologic studies of pertussis. Development of precipitins.", "content": "Immunologic studies of pertussis. Development of precipitins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352206"}
{"pmid": "4352207", "title": "Acceleration of growth and bone maturation in childhood thyrotoxicosis.", "content": "Acceleration of growth and bone maturation in childhood thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352207"}
{"pmid": "4352208", "title": "Insulin secretion in children with constitutional familial short stature.", "content": "Insulin secretion in children with constitutional familial short stature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352208"}
{"pmid": "4352209", "title": "Intravenous alimentation in patients with cancer and neutropenia.", "content": "Intravenous alimentation in patients with cancer and neutropenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352209"}
{"pmid": "4352210", "title": "Central modulation of baroreceptor reflex by angiotensin.", "content": "Central modulation of baroreceptor reflex by angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352210"}
{"pmid": "4352211", "title": "Complications of influenza and their management.", "content": "Complications of influenza and their management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352211"}
{"pmid": "4352212", "title": "Sexual differences in the hypothalamic cholinergic system before and after puberty: inductory effect of testosterone.", "content": "Sexual differences in the hypothalamic cholinergic system before and after puberty: inductory effect of testosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352212"}
{"pmid": "4352213", "title": "The relationship between maternal and neonatal sleep.", "content": "The relationship between maternal and neonatal sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352213"}
{"pmid": "4352215", "title": "Abnormalities of carbohydrate and lipid metabolism in experimentally induced acute uremia.", "content": "Abnormalities of carbohydrate and lipid metabolism in experimentally induced acute uremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352215"}
{"pmid": "4352214", "title": "Serum total lipids and lipid fractions in marasmus.", "content": "Serum total lipids and lipid fractions in marasmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352214"}
{"pmid": "4352217", "title": "A mutant transcription factor that is activated by 3':5'-cyclic guanosine monophosphate.", "content": "A mutant transcription factor that is activated by 3':5'-cyclic guanosine monophosphate. We report here the isolation of an extragenic suppressor of a promoter mutation in the lactose operon of Escherichia coli. Genetic data have indicated that the suppressor of the P(-) mutation maps in the structural gene for the transcription factor catabolite activator protein. Biochemical studies suggest that the mutant molecules of catabolite activator protein are altered in such a way that they are activated by 3':5'-cyclic GMP in addition to their normal effector, 3':5'-cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352217"}
{"pmid": "4352216", "title": "Open-field behavior, habituation and passive avoidance learning: effect of ACTH and hydrocortisone on normal and adrenalectomized rats.", "content": "Open-field behavior, habituation and passive avoidance learning: effect of ACTH and hydrocortisone on normal and adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352216"}
{"pmid": "4352218", "title": "Interaction of amines with ketone aldehydes and unsaturated aldehydes.", "content": "Interaction of amines with ketone aldehydes and unsaturated aldehydes. The optical changes occurring during the interaction of amines with ketone aldehydes or unsaturated aldehydes are accompanied by strong electron spin resonance signals, and can thus be explained as due to the transfer of one whole electron in the ground state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352218"}
{"pmid": "4352219", "title": "Nonvirion antigens produced by herpes simplex viruses 1 and 2.", "content": "Nonvirion antigens produced by herpes simplex viruses 1 and 2. Of nine herpes simplex virus 1 strains (from lip, mouth, throat, cornea, or brain) only five produced enough nonvirion antigen (i.e., not a structural component of the virus) to be detected by complement fixation with specially prepared, virion-absorbed, type-1 guinea pig antisera, while the remaining four strains produced only enough of the same antigen to induce specific antibody in hyperimmunized guinea pigs. While the type 1 virion antiserum used reacted equally well by complement fixation with the type 1 and type 2 strains, the type 1 nonvirion antisera failed to react with nonvirion antigens produced by three type-2 (genital) strains. However, type 2 nonvirion antiserum reacted equally well with the three type 2 and four type 1 nonvirion antigens that were tested. It appears, therefore, that while herpes simplex virus 1 codes only for type 1 nonvirion antigen, herpes simplex 2 codes not only for an immunologically distinct type 2 nonvirion antigen but also for enough type 1 nonvirion antigen to stimulate antibody production for it. Herpes simplex 2 nonvirion antigen exhibited the same properties as type 1, i.e., its activity was lost on storage at 4 degrees for 15 days, it was sedimented by centrifugation at 33,360 x g for 1 hr, and the maximum concentration was found at 3 hr in guinea pig kidney culture cells, but at 24 hr in HEp 2 and rabbit kidney culture cells. Sera from patients with genital lesions caused by herpes simplex virus 2, as well as from randomly selected adults, failed to react with either type 2 or type 1 nonvirion antigens. Accordingly, the basic information is now available to permit the use of these nonvirion antigens to determine the possible role of the herpes simplex viruses in certain human cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352219"}
{"pmid": "4352220", "title": "Purification of mouse interferon by affinity chromatography on a solid-phase immunoadsorbent.", "content": "Purification of mouse interferon by affinity chromatography on a solid-phase immunoadsorbent. A solid-phase immunoadsorbent capable of binding mouse interferon has been prepared. Starting from crude tissue-culture material, interferon could be purified 1990 times in a single step of affinity chromatography. Overall recovery ranged from 55 to 103% with tissue culture and mouse-brain interferon; however, only 5% was obtained with Sendai virus-induced interferon from mouse serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352220"}
{"pmid": "4352221", "title": "Evidence for the absence of the G-T-psi-C sequence from two mammalian initiator transfer RNAs.", "content": "Evidence for the absence of the G-T-psi-C sequence from two mammalian initiator transfer RNAs. Analyses were performed on the purified initiator tRNA from rabbit liver to test for the presence of Psip and Tp in this molecule. Neither of these nucleotides could be detected after hydrolysis by piperidine, NaOH, or T2 RNase. Similarly digestion with venom phosphodiesterase plus phosphatase failed to release any pseudourdine or ribothymidine. Identical results were obtained with the initiator tRNA from sheep mammary gland. The absence of these nucleosides was confirmed by pancreatic and T1 RNase digestion of the rabbit-liver initiator tRNA. The classical G-T-Psi-C sequence was not detected in this molecule. An A-U-C-G sequence has been identified; it may possibly replace the G-T-Psi-C sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352221"}
{"pmid": "4352223", "title": "Effects of adrenal glucocorticoids on polyoma virus replication.", "content": "Effects of adrenal glucocorticoids on polyoma virus replication. Treatment of polyoma virus-infected fibroblasts from mouse embryos and virus-infected 3T3 cells with physiological concentrations of the glucocorticoids enhances plaque formation at least 10-fold. The data suggest that this effect results from an increased rate of virus production. Steroid specificity studies indicate that the cytoplasmic receptors that mediate the physiological actions of these hormones are also involved in the present effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352223"}
{"pmid": "4352225", "title": "Amino-acid acceptor activity of the \"70S-associated\" 4S RNA from avian myeloblastosis virus.", "content": "Amino-acid acceptor activity of the \"70S-associated\" 4S RNA from avian myeloblastosis virus. The \"70S-associated\" 4S RNA from avian myeloblastosis virus contains transfer RNA, as determined by aminoacylation. The various amino acids esterified, plus the great number of minor bases found in this \"70S-associated\" 4S RNA indicate that a sizeable fraction, but not all, of this RNA is transfer RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352225"}
{"pmid": "4352222", "title": "Transformation of chick-embryo fibroblasts by wild-type and temperature-sensitive Rous sarcoma virus alters adenylate cyclase activity.", "content": "Transformation of chick-embryo fibroblasts by wild-type and temperature-sensitive Rous sarcoma virus alters adenylate cyclase activity. The activity of the enzyme adenylate cyclase, a component of the plasma membrane, has been determined in chick-embryo fibroblasts and in cells transformed by either Bryan high-titer strain of Rous sarcoma virus (RSV-BH) or a temperature-sensitive mutant of this virus (RSV-BH-Ta). Adenylate cyclase activity is reduced in cells transformed by the wild-type virus and also by the temperature-sensitive mutant when the cells are grown at the permissive temperature (37 degrees ). Transformation results in an altered affinity (K(m)) for the substrate (Mg ATP). The apparent K(m) ATP is 0.23 mM in normal cells and 1.1 mM in cells transformed with wild-type virus. The K(m) ATP of the cells infected with RSV-BH-Ta is 0.67-1.0 mM at 37 degrees and 0.28 mM at 42 degrees . The enzyme from normal cells appears to have two binding sites for Mg(++), one at the catalytic site and a second at a regulatory site. Transformation by RSV-BH or RSV-BH-Ta (37 degrees ) apparently alters this second Mg(++) site. A decrease in adenylate cyclase activity occurs within 10 min after cells infected with RSV-BH-Ta are shifted from 42 degrees to 37 degrees ; the activity falls to one-half that of normal cells 30 min after the temperature shift. Our observations indicate that a viral function lowers cyclic AMP content by lowering the activity of adenylate cyclase, probably through some modification of the plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352222"}
{"pmid": "4352224", "title": "Activation of prolyl hydroxylase in L-929 fibroblasts by ascorbic acid.", "content": "Activation of prolyl hydroxylase in L-929 fibroblasts by ascorbic acid. The addition of ascorbate to the culture medium of early log-phase mouse fibroblasts (L-929 cells) resulted in a 5-fold increase of prolyl hydroxylase activity. Maximal activity was reached within 2 hr after addition of 5 muM ascorbate. The total amount of enzyme-related antigen did not change on treatment with ascorbate and the activation was shown to be independent of RNA and protein synthesis. The increase in activity caused by ascorbate is therefore due to the activation of a preformed precursor. Enzyme (molecular weight 260,000-300,000) and putative precursor (molecular weight 85,000-105,000) were separated by chromatography on DEAE-Sephadex. Treatment of intact cells with dithiothreitol resulted in an almost quantitative conversion of the enzyme to the smaller inactive protein. When these cells were treated with ascorbate or incubated overnight in fresh medium the enzyme reappeared and precursor concentrations decreased proportionately. Ascorbate may act by bringing about aggregation of enzymatically inactive subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352224"}
{"pmid": "4352227", "title": "A physiological mechanism for Hebb's postulate of learning.", "content": "A physiological mechanism for Hebb's postulate of learning. Hebb's postulate of learning envisages that activation or inactivation of extant synaptic contacts in plastic neural networks depends on the synchronous impulse activity of pre- and postsynaptic nerve cells. The physiological mechanism proposed here for this process posits that at synapses acting according to Hebb's postulate, the receptors for the neurotransmitter are eliminated from the postsynaptic membrane by the transient reversals of the sign of membrane polarization that occur during action potential impulses in the postsynaptic cell. But, since the release of neurotransmitter drives the membrane potential of the synaptic zone towards a level about half-way between the negative-inside resting potential and the positive-inside action potential, it would follow that the membrane patches surrounding the receptors of a synapse whose activity has contributed to setting off the postsynaptic impulse would be spared the full extent of the noxious polarity reversal. This mechanism can account for a neurophysiologically documented example of the operation of Hebb's postulate, namely the plasticity of the connections between fourth- and fifth-order neurons in the visual cortex of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352227"}
{"pmid": "4352226", "title": "Continuous propagation of radiation leukemia virus on a C57BL mouse-embryo fibroblast line, with attenuation of leukemogenic activity.", "content": "Continuous propagation of radiation leukemia virus on a C57BL mouse-embryo fibroblast line, with attenuation of leukemogenic activity. The radiation leukemia virus (RadLV), a murine leukemia virus derived from thymic lymphomas induced by x-irradiation in strain C57BL/Ka mice, has been successfully propagated in sustained high titer in vitro in a newly established line, BL-5, of C57BL/Ka mouse-embryo fibroblasts. In addition, the production of endogenous virus, presumed to be RadLV, has been induced and sustained through multiple serial passages after treatment of BL-5 cell cultures with 5-bromodeoxyuridine. The chronically RadLV-infected subline, designated BL-5 (RadLV), sheds virus into the supernatant culture fluids that is biologically active in vitro in the XC cell plaque assay, in interference assays for focus-formation by murine sarcoma virus, and in the intracellular induction of group-specific antigens detectable by immunofluorescence, but is apparently devoid of leukemogenic activity after intrathymic inoculation into neonatal or immunosuppressed C57BL/Ka mice. Although BL-5 cells exhibited morphological alterations suggestive of transformation in vitro and gave rise to fibrosarcomatous ascites tumors after intraperitoneal inoculation with C57BL/Ka mice, the chronically infected BL-5(RadLV) cells remained normal in morphology and failed to yield fibrosarcomas in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352226"}
{"pmid": "4352228", "title": "Pituitary-adrenal responsiveness in surgical patients on acute and chronic corticosteroid therapy: plasma corticosterone assay.", "content": "Pituitary-adrenal responsiveness in surgical patients on acute and chronic corticosteroid therapy: plasma corticosterone assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352228"}
{"pmid": "4352229", "title": "On the fine structure of horse sweat glands.", "content": "On the fine structure of horse sweat glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352229"}
{"pmid": "4352230", "title": "The effect of aminophylline on pentagastrin-induced gastric secretion in the dog.", "content": "The effect of aminophylline on pentagastrin-induced gastric secretion in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352230"}
{"pmid": "4352231", "title": "Sequential immunization procedure against Group B arboviruses using living attenuated 17D yellow fever virus, living attenuated Langat E5 virus, and living attenuated dengue 2 virus (New Guinea C isolate).", "content": "Sequential immunization procedure against Group B arboviruses using living attenuated 17D yellow fever virus, living attenuated Langat E5 virus, and living attenuated dengue 2 virus (New Guinea C isolate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352231"}
{"pmid": "4352233", "title": "Axillary metastases from unknown primary sites.", "content": "Axillary metastases from unknown primary sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352233"}
{"pmid": "4352232", "title": "Passive immunity for arbovirus infection. II. Quantitative aspects of naturally and artificially acquired protection in mice for Japanese (B) encephalitis virus.", "content": "Passive immunity for arbovirus infection. II. Quantitative aspects of naturally and artificially acquired protection in mice for Japanese (B) encephalitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352232"}
{"pmid": "4352235", "title": "Crystalloid inclusions in the Schwann cell cytoplasm.", "content": "Crystalloid inclusions in the Schwann cell cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352235"}
{"pmid": "4352234", "title": "The evaluation of a new peritoneoscope as a diagnostic aid to the surgeon.", "content": "The evaluation of a new peritoneoscope as a diagnostic aid to the surgeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352234"}
{"pmid": "4352236", "title": "Evidence that endogenous cyclic AMP does not modulate serum sulfation factor action on embryonic chicken cartilage.", "content": "Evidence that endogenous cyclic AMP does not modulate serum sulfation factor action on embryonic chicken cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352236"}
{"pmid": "4352237", "title": "Induction of serine dehydratase activity by cyclic AMP is restricted to S phase in synchronized CHO cells.", "content": "Induction of serine dehydratase activity by cyclic AMP is restricted to S phase in synchronized CHO cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352237"}
{"pmid": "4352238", "title": "Amino acid compositions of simian virus 40 structural proteins.", "content": "Amino acid compositions of simian virus 40 structural proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352238"}
{"pmid": "4352239", "title": "Inhibition of Escherichia coli growth by cyclic adenosine 3', 5'-monophosphate.", "content": "Inhibition of Escherichia coli growth by cyclic adenosine 3', 5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352239"}
{"pmid": "4352240", "title": "Association of prolyl hydroxylase activity with membranes.", "content": "Association of prolyl hydroxylase activity with membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352240"}
{"pmid": "4352241", "title": "Adenylate cyclase activity is decreased in chick embryo fibroblasts transformed by wild type and temperature sensitive Schmidt-Ruppin Rous sarcoma virus.", "content": "Adenylate cyclase activity is decreased in chick embryo fibroblasts transformed by wild type and temperature sensitive Schmidt-Ruppin Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352241"}
{"pmid": "4352242", "title": "Occurrence of cis-7-tetradecenoic acid in the envelope phospholipids of Escherichia coli K12.", "content": "Occurrence of cis-7-tetradecenoic acid in the envelope phospholipids of Escherichia coli K12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352242"}
{"pmid": "4352243", "title": "Polyriboadenylate synthesizing activity in chromatin of wheat seedlings.", "content": "Polyriboadenylate synthesizing activity in chromatin of wheat seedlings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352243"}
{"pmid": "4352244", "title": "The inhibition of the avian myeloblastosis virus DNA polymerase by poly(U) fractions of varying chain length.", "content": "The inhibition of the avian myeloblastosis virus DNA polymerase by poly(U) fractions of varying chain length.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352244"}
{"pmid": "4352245", "title": "Identification and extent of fluid bilayer regions in membranous cytochrome oxidase.", "content": "Identification and extent of fluid bilayer regions in membranous cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352245"}
{"pmid": "4352246", "title": "A rapid method for the isolation of rat liver plasma membranes using an aqueous two-phase polymer system.", "content": "A rapid method for the isolation of rat liver plasma membranes using an aqueous two-phase polymer system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352246"}
{"pmid": "4352247", "title": "Localization of an RNA-degrading system of enzymes on the rat liver plasma membrane.", "content": "Localization of an RNA-degrading system of enzymes on the rat liver plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352247"}
{"pmid": "4352251", "title": "Space-time clustering of limb defects in Cardiff.", "content": "Space-time clustering of limb defects in Cardiff.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352251"}
{"pmid": "4352253", "title": "Settlement of Mr. Kenneth Robinson's libel action.", "content": "Settlement of Mr. Kenneth Robinson's libel action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352253"}
{"pmid": "4352252", "title": "Infectious mononucleosis.", "content": "Infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352252"}
{"pmid": "4352254", "title": "Cell-mediated immunity to Varicella-Zoster antigen in acute Herpes zoster (shingles).", "content": "Cell-mediated immunity to Varicella-Zoster antigen in acute Herpes zoster (shingles).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352254"}
{"pmid": "4352255", "title": "Immunoconglutinin response in patients with acute viral respiratory disease.", "content": "Immunoconglutinin response in patients with acute viral respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352255"}
{"pmid": "4352256", "title": "Magnetic-circular-dichroism studies of cytochrome c and cytochrome b 2 .", "content": "Magnetic-circular-dichroism studies of cytochrome c and cytochrome b 2 .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352256"}
{"pmid": "4352257", "title": "Oxidation of acetaldehyde by rat-liver mitochondria in relation to ethanol oxidation and the transport of reducing equivalents across the mitochondrial membrane.", "content": "Oxidation of acetaldehyde by rat-liver mitochondria in relation to ethanol oxidation and the transport of reducing equivalents across the mitochondrial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352257"}
{"pmid": "4352258", "title": "Molecular weight and subunit structure of the malate-lactate transhydrogenase.", "content": "Molecular weight and subunit structure of the malate-lactate transhydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352258"}
{"pmid": "4352259", "title": "Studies on metabolism of lung flukes of the genus Paragonimus. VI. Succinoxidase system in homogenates of eggs, larvae, and adults.", "content": "Studies on metabolism of lung flukes of the genus Paragonimus. VI. Succinoxidase system in homogenates of eggs, larvae, and adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352259"}
{"pmid": "4352260", "title": "Plasma renin studies in patients with traumatic spinal cord injuries.", "content": "Plasma renin studies in patients with traumatic spinal cord injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352260"}
{"pmid": "4352261", "title": "Limb-girdle muscular dystrophy. Case report with electron microscopic study of a muscle biopsy.", "content": "Limb-girdle muscular dystrophy. Case report with electron microscopic study of a muscle biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352261"}
{"pmid": "4352262", "title": "Growth and development of children with Legg-Calvé-Perthes syndrome in Israel.", "content": "Growth and development of children with Legg-Calvé-Perthes syndrome in Israel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352262"}
{"pmid": "4352263", "title": "The detection of Clostridium welchii in the differential reinforced clostridial medium technique.", "content": "The detection of Clostridium welchii in the differential reinforced clostridial medium technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352263"}
{"pmid": "4352265", "title": "Nitroblue tetrazolium reduction by neutrophils: biochemical and ultrastructural effects of methylene blue.", "content": "Nitroblue tetrazolium reduction by neutrophils: biochemical and ultrastructural effects of methylene blue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352265"}
{"pmid": "4352266", "title": "Studies on the mechanism of inflammation induced by calcium pyrophosphate crystals.", "content": "Studies on the mechanism of inflammation induced by calcium pyrophosphate crystals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352266"}
{"pmid": "4352268", "title": "Intrathecal gentamicin in treatment of bacterial meningitis.", "content": "Intrathecal gentamicin in treatment of bacterial meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352268"}
{"pmid": "4352267", "title": "Dose-response to lead ingestion in rats fed low dietary calcium.", "content": "Dose-response to lead ingestion in rats fed low dietary calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352267"}
{"pmid": "4352270", "title": "Twenty-four hour patterns of plasma luteinizing hormone and follicle-stimulating hormone in sexual precocity.", "content": "Twenty-four hour patterns of plasma luteinizing hormone and follicle-stimulating hormone in sexual precocity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352270"}
{"pmid": "4352272", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 32-1973.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 32-1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352272"}
{"pmid": "4352271", "title": "Clinical dermatology (third of three parts).", "content": "Clinical dermatology (third of three parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352271"}
{"pmid": "4352283", "title": "Lead inclusion bodies in osteoclasts.", "content": "Lead inclusion bodies in osteoclasts. Inclusion bodies occur frequently in the nuclei and rarely in the cytoplasm of osteoclasts in pigs with experimental lead poisoning. The light and electron microscope pictures of undemineralized sections are similar to those described for liver cord cells and renal tubular cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352283"}
{"pmid": "4352284", "title": "The prolactin cell of the white-crowned sparrow, Zonotrichia leucophrys pugetensis.", "content": "The prolactin cell of the white-crowned sparrow, Zonotrichia leucophrys pugetensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352284"}
{"pmid": "4352285", "title": "Ultrastructure of the aesthetase hairs of the littoral decapod, Paragrapsus gaimardii.", "content": "Ultrastructure of the aesthetase hairs of the littoral decapod, Paragrapsus gaimardii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352285"}
{"pmid": "4352286", "title": "The fine structure of the lutein cells in the mink (Mustela vison) with special reference to the secretory activity during pregnancy.", "content": "The fine structure of the lutein cells in the mink (Mustela vison) with special reference to the secretory activity during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352286"}
{"pmid": "4352287", "title": "The ultrastructural arrangement of thrombosthenin in glycerol extracted thrombocytes.", "content": "The ultrastructural arrangement of thrombosthenin in glycerol extracted thrombocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352287"}
{"pmid": "4352288", "title": "Progressive external ophthalmoplegia--some clinical associations.", "content": "Progressive external ophthalmoplegia--some clinical associations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352288"}
{"pmid": "4352289", "title": "An attempt to explain nervous transmitter release as due to nerve impulse-induced cation exchange.", "content": "An attempt to explain nervous transmitter release as due to nerve impulse-induced cation exchange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352289"}
{"pmid": "4352290", "title": "Degeneration activity in the rat urinary bladder.", "content": "Degeneration activity in the rat urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352290"}
{"pmid": "4352291", "title": "Afferent discharges via the laryngeal communicans related to respiration in the rat.", "content": "Afferent discharges via the laryngeal communicans related to respiration in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352291"}
{"pmid": "4352292", "title": "High-pressure anion exchange chromatography and enzymatic isotope displacement assays for cyclic AMP and cyclic GMP.", "content": "High-pressure anion exchange chromatography and enzymatic isotope displacement assays for cyclic AMP and cyclic GMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352292"}
{"pmid": "4352294", "title": "Saturation assay for cyclic AMP using endogenous binding protein.", "content": "Saturation assay for cyclic AMP using endogenous binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352294"}
{"pmid": "4352293", "title": "Determination of relative levels of cyclic AMP in tissues or cells prelabeled with radioactive adenine.", "content": "Determination of relative levels of cyclic AMP in tissues or cells prelabeled with radioactive adenine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352293"}
{"pmid": "4352295", "title": "An assay method for cyclic AMP and cyclic GMP based upon their abilities to activate cyclic AMP-dependent and cyclic GMP-dependent protein kinases.", "content": "An assay method for cyclic AMP and cyclic GMP based upon their abilities to activate cyclic AMP-dependent and cyclic GMP-dependent protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352295"}
{"pmid": "4352296", "title": "Radioimmunoassay for the measurement of cyclic nucleotides.", "content": "Radioimmunoassay for the measurement of cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352296"}
{"pmid": "4352298", "title": "The luminescence assay of cyclic AMP.", "content": "The luminescence assay of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352298"}
{"pmid": "4352297", "title": "Analysis of cyclic AMP and cyclic GMP by enzymic cycling procedures.", "content": "Analysis of cyclic AMP and cyclic GMP by enzymic cycling procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352297"}
{"pmid": "4352299", "title": "Firefly luminescence in the assay of cyclic AMP.", "content": "Firefly luminescence in the assay of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352299"}
{"pmid": "4352300", "title": "Protein binding assays for cyclic nucleotides.", "content": "Protein binding assays for cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352300"}
{"pmid": "4352301", "title": "Herpesvirus type 2 in genitourinary tract infections.", "content": "Herpesvirus type 2 in genitourinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352301"}
{"pmid": "4352302", "title": "Effects of sonication on physicochemical and biological properties of synthetic double-stranded polyribonucleotides as interferon inducer.", "content": "Effects of sonication on physicochemical and biological properties of synthetic double-stranded polyribonucleotides as interferon inducer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352302"}
{"pmid": "4352303", "title": "Inhibitory effect of N-phenyl-N'-aryl or alkylthiourea derivatives on the multiplication of some picornaviruses (Coxsackie B 1, ECHO 19, and foot-and-mouth disease virus) in cell cultures.", "content": "Inhibitory effect of N-phenyl-N'-aryl or alkylthiourea derivatives on the multiplication of some picornaviruses (Coxsackie B 1, ECHO 19, and foot-and-mouth disease virus) in cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352303"}
{"pmid": "4352305", "title": "Infection of chick embryo tracheal organ cultures with influenza A2 (Hong Kong) virus. II. Electron microscopy.", "content": "Infection of chick embryo tracheal organ cultures with influenza A2 (Hong Kong) virus. II. Electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352305"}
{"pmid": "4352306", "title": "The use of frozen cells in the agar-cell suspension titration technique. A reproducible system. Brief report.", "content": "The use of frozen cells in the agar-cell suspension titration technique. A reproducible system. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352306"}
{"pmid": "4352308", "title": "The ultrastructure of acute silicosis.", "content": "The ultrastructure of acute silicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352308"}
{"pmid": "4352307", "title": "Bovine virus diarrhoea virus: acquired resistance to acriflavine. Brief report.", "content": "Bovine virus diarrhoea virus: acquired resistance to acriflavine. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352307"}
{"pmid": "4352309", "title": "Morphological effects of Compound 48-80, polymyxin B sulfate, and dextran on rat skeletal muscle.", "content": "Morphological effects of Compound 48-80, polymyxin B sulfate, and dextran on rat skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352309"}
{"pmid": "4352311", "title": "Possible role of cyclic AMP in gastric acid secretion in rat. Activation of carbonic anhydrase.", "content": "Possible role of cyclic AMP in gastric acid secretion in rat. Activation of carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352311"}
{"pmid": "4352310", "title": "Multifocal granular cell myoblastoma. Report of a case involving trachea, stomach, and anterior abdominal wall.", "content": "Multifocal granular cell myoblastoma. Report of a case involving trachea, stomach, and anterior abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352310"}
{"pmid": "4352312", "title": "The use of tetanic and single twitch stimuli to assess neuromuscular block in man.", "content": "The use of tetanic and single twitch stimuli to assess neuromuscular block in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352312"}
{"pmid": "4352313", "title": "The effects of oestrogen, ACTH and cortisone administration and hypophysectomy on histological changes induced by unilateral renal pedicle clamping.", "content": "The effects of oestrogen, ACTH and cortisone administration and hypophysectomy on histological changes induced by unilateral renal pedicle clamping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352313"}
{"pmid": "4352315", "title": "Significance of high plasma renin activity in patients on maintenance haemodialysis therapy.", "content": "Significance of high plasma renin activity in patients on maintenance haemodialysis therapy. Blood pressure and plasma renin activity were remeasured after an interval of 8 to 17 months in 16 patients on maintenance haemodialysis previously found to have high renin activity. Continuing intermittent haemodialysis changed the plasma renin activity and blood pressure but no consistent pattern was seen. This confirmed our previous finding that adequate dialysis can control blood pressure in the presence of high renin activity. We therefore conclude that bilateral nephrectomy should be approached with renewed caution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352315"}
{"pmid": "4352314", "title": "Immunological assessment of mice with chronic jaundice and runting induced by reovirus 3.", "content": "Immunological assessment of mice with chronic jaundice and runting induced by reovirus 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352314"}
{"pmid": "4352316", "title": "Oestrogen receptor in human breast cancer tissue and response to endocrine therapy.", "content": "Oestrogen receptor in human breast cancer tissue and response to endocrine therapy. Oestrogen receptor determinations were done in metastatic breast cancer tissue of patients with advanced breast cancer. In 37 patients with progressive disease evaluation of the response to endocrine treatment was possible, following the criteria of the E.O.R.T.C. Co-operative Breast Cancer Group. In 20 patients with receptor-negative tumours two objective remissions were noted; in 17 patients with receptor-positive tumours 14 objective remissions were seen. There seems to be a striking correlation between the presence or absence of oestrogen receptor in tumour tissue and the clinical response to hormonal therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352316"}
{"pmid": "4352319", "title": "Radioimmunoassay for plasma renin activity.", "content": "Radioimmunoassay for plasma renin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352319"}
{"pmid": "4352320", "title": "A sensitive bioassay for adrenocorticotrophic hormone in human plasma.", "content": "A sensitive bioassay for adrenocorticotrophic hormone in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352320"}
{"pmid": "4352321", "title": "Urinary pregnanediol and pregnanetriol in the salt-losing and nonsalt-losing forms of C-21-hydroxylase deficiency.", "content": "Urinary pregnanediol and pregnanetriol in the salt-losing and nonsalt-losing forms of C-21-hydroxylase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352321"}
{"pmid": "4352322", "title": "Cystosarcoma phyllodes.", "content": "Cystosarcoma phyllodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352322"}
{"pmid": "4352323", "title": "Effect of 1-naphthyl isothiocyanate and 3-methylcholanthrene on hepatocarcinogenesis in rats treated with diethylnitrosoamine.", "content": "Effect of 1-naphthyl isothiocyanate and 3-methylcholanthrene on hepatocarcinogenesis in rats treated with diethylnitrosoamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352323"}
{"pmid": "4352324", "title": "Relations between postnatal days of mice and carcinogenic effect of cycasin.", "content": "Relations between postnatal days of mice and carcinogenic effect of cycasin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352324"}
{"pmid": "4352325", "title": "Influence of vascular permeability on blood-borne metastasis.", "content": "Influence of vascular permeability on blood-borne metastasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352325"}
{"pmid": "4352327", "title": "Virus-like particles observed in transplantable intrahepatic bile duct carcinomas and hepatoma of Syrian golden hamsters.", "content": "Virus-like particles observed in transplantable intrahepatic bile duct carcinomas and hepatoma of Syrian golden hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352327"}
{"pmid": "4352326", "title": "Inhibitory effect of a streptococcal preparation (OK-432) on the nucleic acid synthesis in tumor cells in vitro.", "content": "Inhibitory effect of a streptococcal preparation (OK-432) on the nucleic acid synthesis in tumor cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352326"}
{"pmid": "4352328", "title": "Carcinoma of the large intestine of rats induced by rectal infusion of methylazoxymethanol.", "content": "Carcinoma of the large intestine of rats induced by rectal infusion of methylazoxymethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352328"}
{"pmid": "4352330", "title": "A new method for the investigation of the kinetics of the capture reaction in phosphatase cytochemistry. I. Theoretical aspects of the local formation of crystalline precipitates.", "content": "A new method for the investigation of the kinetics of the capture reaction in phosphatase cytochemistry. I. Theoretical aspects of the local formation of crystalline precipitates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352330"}
{"pmid": "4352329", "title": "What a dietitian should know about hyperlipidemia.", "content": "What a dietitian should know about hyperlipidemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352329"}
{"pmid": "4352317", "title": "The vanishing chronic. The reduction of the resident patient population of a large urban Ontario mental hospital from 1950 to 1970 with an analysis of associated administrative and therapeutic changes.", "content": "The vanishing chronic. The reduction of the resident patient population of a large urban Ontario mental hospital from 1950 to 1970 with an analysis of associated administrative and therapeutic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352317"}
{"pmid": "4352331", "title": "A new method for the investigation of the kinetics of the capture reaction in phosphatase cytochemistry. II. Theoretical and experimental study of phosphate diffusion from thin polyacrylamide films.", "content": "A new method for the investigation of the kinetics of the capture reaction in phosphatase cytochemistry. II. Theoretical and experimental study of phosphate diffusion from thin polyacrylamide films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352331"}
{"pmid": "4352333", "title": "Angiotensin II analogs. 10. Stereochemical factors in the 5 position influencing pressor activity.", "content": "Angiotensin II analogs. 10. Stereochemical factors in the 5 position influencing pressor activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352333"}
{"pmid": "4352332", "title": "Neutralizing activity in human sera against the leukocyte-transforming agent.", "content": "Neutralizing activity in human sera against the leukocyte-transforming agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352332"}
{"pmid": "4352334", "title": "6-Substituted 5-chloro-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-ones with hypotensive activity.", "content": "6-Substituted 5-chloro-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-ones with hypotensive activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352334"}
{"pmid": "4352337", "title": "Antibiotics and the kidney.", "content": "Antibiotics and the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352337"}
{"pmid": "4352342", "title": "Viral cystitis.", "content": "Viral cystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352342"}
{"pmid": "4352341", "title": "Further study on acute hemorrhagic cystitis due to adenovirus type 11.", "content": "Further study on acute hemorrhagic cystitis due to adenovirus type 11.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352341"}
{"pmid": "4352344", "title": "Stomach contractions at REM sleep in goats and sheep.", "content": "Stomach contractions at REM sleep in goats and sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352344"}
{"pmid": "4352343", "title": "Transplantability of avian lymphoid tumor cells.", "content": "Transplantability of avian lymphoid tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352343"}
{"pmid": "4352345", "title": "Acetylcholine-dependent molecular receptor. Activation of triphosphoinositide phosphomonoesterase.", "content": "Acetylcholine-dependent molecular receptor. Activation of triphosphoinositide phosphomonoesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352345"}
{"pmid": "4352346", "title": "Oral tumours in Kenya.", "content": "Oral tumours in Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352346"}
{"pmid": "4352347", "title": "Normal structure, ultrastructure and enzyme content of glomic cells.", "content": "Normal structure, ultrastructure and enzyme content of glomic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352347"}
{"pmid": "4352348", "title": "Roentgen and telecobalt therapy of tumors of the brain.", "content": "Roentgen and telecobalt therapy of tumors of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352348"}
{"pmid": "4352339", "title": "Electroneuroprostheses: past and present uses in man.", "content": "Electroneuroprostheses: past and present uses in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352339"}
{"pmid": "4352340", "title": "Ceramics, glasses, and composites in medicine.", "content": "Ceramics, glasses, and composites in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352340"}
{"pmid": "4352351", "title": "Is there a vestibulo-spinal reflex contribution to running?", "content": "Is there a vestibulo-spinal reflex contribution to running?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352351"}
{"pmid": "4352350", "title": "Cerebral hemodynamics in carotid surgery.", "content": "Cerebral hemodynamics in carotid surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352350"}
{"pmid": "4352353", "title": "Experimental cerebellar uvulonodular lesions in the squirrel monkey.", "content": "Experimental cerebellar uvulonodular lesions in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352353"}
{"pmid": "4352352", "title": "The vestibular thalamus in the rhesus monkey.", "content": "The vestibular thalamus in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352352"}
{"pmid": "4352354", "title": "Galvanic body sway in normals and patients with 8th nerve lesions.", "content": "Galvanic body sway in normals and patients with 8th nerve lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352354"}
{"pmid": "4352355", "title": "Studies on methanol-oxidizing bacteria. I. Isolation and growth studies.", "content": "Studies on methanol-oxidizing bacteria. I. Isolation and growth studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352355"}
{"pmid": "4352360", "title": "Long-acting phenothiazines in the prevention of relapse of schizophrenic patients.", "content": "Long-acting phenothiazines in the prevention of relapse of schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352360"}
{"pmid": "4352361", "title": "Potentiation of rifampicin, rifampicin analogs, and tetracycline against animal cells by amphotericin B and polymyxin B.", "content": "Potentiation of rifampicin, rifampicin analogs, and tetracycline against animal cells by amphotericin B and polymyxin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352361"}
{"pmid": "4352363", "title": "DNA polymerases I and II in regenerating rat liver and Morris hepatomas.", "content": "DNA polymerases I and II in regenerating rat liver and Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352363"}
{"pmid": "4352362", "title": "A comparative study of some properties of chromatin from two \"minimal deviation\" hepatomas.", "content": "A comparative study of some properties of chromatin from two \"minimal deviation\" hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352362"}
{"pmid": "4352364", "title": "Viropexis of type B particles in reticulum cell sarcoma of R3-Dm strain mice.", "content": "Viropexis of type B particles in reticulum cell sarcoma of R3-Dm strain mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352364"}
{"pmid": "4352365", "title": "Vincristine treatment of advanced cancer: a cooperative study of 392 cases.", "content": "Vincristine treatment of advanced cancer: a cooperative study of 392 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352365"}
{"pmid": "4352367", "title": "Poly(adenosine diphosphate ribose) synthesis during the cell cycle of transformed hamster lung cells.", "content": "Poly(adenosine diphosphate ribose) synthesis during the cell cycle of transformed hamster lung cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352367"}
{"pmid": "4352366", "title": "Separable DNA polymerase activities in host liver and Morris hepatomas.", "content": "Separable DNA polymerase activities in host liver and Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352366"}
{"pmid": "4352368", "title": "Protein turnover in microsomal subfractions of liver and Morris hepatomas 7800 and 9618A.", "content": "Protein turnover in microsomal subfractions of liver and Morris hepatomas 7800 and 9618A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352368"}
{"pmid": "4352369", "title": "Rapid arrest of DNA synthesis by N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate in cultured hepatoma cells.", "content": "Rapid arrest of DNA synthesis by N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate in cultured hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352369"}
{"pmid": "4352370", "title": "Protection against radiation leukemogenesis by repeated injections of immune and nonimmune foreign sera.", "content": "Protection against radiation leukemogenesis by repeated injections of immune and nonimmune foreign sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352370"}
{"pmid": "4352372", "title": "A selective review of experimental studies in cervical carcinoma.", "content": "A selective review of experimental studies in cervical carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352372"}
{"pmid": "4352371", "title": "A comparison review of key epidemiological studies in cervical cancer related to current searches for transmissible agents.", "content": "A comparison review of key epidemiological studies in cervical cancer related to current searches for transmissible agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352371"}
{"pmid": "4352373", "title": "Latent infections induced by herpes simplex viruses.", "content": "Latent infections induced by herpes simplex viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352373"}
{"pmid": "4352375", "title": "Summary of informal discussion on general aspects of herpesviruses.", "content": "Summary of informal discussion on general aspects of herpesviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352375"}
{"pmid": "4352374", "title": "The transcription and state of herpes simplex virus DNA in productive infection and in human cervical cancer tissue.", "content": "The transcription and state of herpes simplex virus DNA in productive infection and in human cervical cancer tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352374"}
{"pmid": "4352376", "title": "Evidence for an oncogenic potential of the Epstein-Barr virus.", "content": "Evidence for an oncogenic potential of the Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352376"}
{"pmid": "4352377", "title": "Simian herpesviruses.", "content": "Simian herpesviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352377"}
{"pmid": "4352378", "title": "Oncogenicity of rabbit herpesvirus.", "content": "Oncogenicity of rabbit herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352378"}
{"pmid": "4352379", "title": "Oncogenic potential of guinea pig herpes- and C-type viruses.", "content": "Oncogenic potential of guinea pig herpes- and C-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352379"}
{"pmid": "4352380", "title": "Summary of informal discussion on oncogenicity of other herpesviruses.", "content": "Summary of informal discussion on oncogenicity of other herpesviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352380"}
{"pmid": "4352381", "title": "Clinical features of herpes genitalis.", "content": "Clinical features of herpes genitalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352381"}
{"pmid": "4352383", "title": "Summary of informal discussion of part I of genital herpesvirus.", "content": "Summary of informal discussion of part I of genital herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352383"}
{"pmid": "4352382", "title": "Relation of cytohistopathology of genital herpesvirus infection to cervical anaplasia.", "content": "Relation of cytohistopathology of genital herpesvirus infection to cervical anaplasia. Cytological changes resulting from herpes simplex virus (HSV) were detected in 673 (.26%) of 279,589 cervicovaginal smears from an indigent hospital population.  Histopathological features of HSV infection were observed in 45 of 126 biopsies taken from the group of 673.  Most of the lesions were multifocal and were located on the squamocolumnar junction;  diagnostic cells were found at the base of normal squamous epithelium or at the surface of anaplastic epithelium.  The cytological and histological changes and diagnostic procedures for HSV infection are given in detail;  cytological detection is 2/3 as sensitive as viral isolation.  The presence of anaplasia in about 2/3 of the 673 HSV cases either before or at the same time as the detection of HSV suggests that anaplastic tissue is more susceptible to HSV infection.  However, serological evidence showing HSV antibodies before the onset of cervical anaplasia, the recurring nature of HSV, and epidemiological evidence showing the age of acquisition of HSV to be 5-30 years before diagnosis of cervical cancer are all compatible with the view that HSV causes cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352382"}
{"pmid": "4352384", "title": "A review of the identification and titration of antibodies to herpes simplex viruses type 1 and type 2 in human sera.", "content": "A review of the identification and titration of antibodies to herpes simplex viruses type 1 and type 2 in human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352384"}
{"pmid": "4352386", "title": "Possible etiologies of cancer of the cervix other than herpesvirus.", "content": "Possible etiologies of cancer of the cervix other than herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352386"}
{"pmid": "4352385", "title": "An analysis of seroepidemiological studies of herpesvirus type 2 and carcinoma of the cervix.", "content": "An analysis of seroepidemiological studies of herpesvirus type 2 and carcinoma of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352385"}
{"pmid": "4352387", "title": "Prospective studies of the association of genital herpes simplex infection and cervical anaplasia.", "content": "Prospective studies of the association of genital herpes simplex infection and cervical anaplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352387"}
{"pmid": "4352388", "title": "Effect of herpesvirus type 2 and hormonal imbalance on the uterine cervix of the mouse.", "content": "Effect of herpesvirus type 2 and hormonal imbalance on the uterine cervix of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352388"}
{"pmid": "4352389", "title": "Herpesvirus and cervical cancer studies in experimental animals.", "content": "Herpesvirus and cervical cancer studies in experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352389"}
{"pmid": "4352390", "title": "Summary of informal discussion of part 3 of genital herpesvirus and of in vivo animal studies.", "content": "Summary of informal discussion of part 3 of genital herpesvirus and of in vivo animal studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352390"}
{"pmid": "4352392", "title": "Human embryonic lung cells transformed by herpes simplex virus.", "content": "Human embryonic lung cells transformed by herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352392"}
{"pmid": "4352391", "title": "Transformation of hamster embryo fibroblasts by herpes simplex viruses type 1 and type 2.", "content": "Transformation of hamster embryo fibroblasts by herpes simplex viruses type 1 and type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352391"}
{"pmid": "4352393", "title": "Virions and antigens of herpes virus type 2 in cervical carcinoma.", "content": "Virions and antigens of herpes virus type 2 in cervical carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352393"}
{"pmid": "4352394", "title": "Nucleic acid hybridization and the relationship between cervical cancer and herpes simplex virus type 2.", "content": "Nucleic acid hybridization and the relationship between cervical cancer and herpes simplex virus type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352394"}
{"pmid": "4352395", "title": "Summary of informal discussion of experimental approaches.", "content": "Summary of informal discussion of experimental approaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352395"}
{"pmid": "4352396", "title": "Symposium on herpesvirus and cervical cancer. Epilog.", "content": "Symposium on herpesvirus and cervical cancer. Epilog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352396"}
{"pmid": "4352397", "title": "Summary of papers delivered at the Conference on Herpesvirus and Cervical Cancer (Key Biscayne, Florida).", "content": "Summary of papers delivered at the Conference on Herpesvirus and Cervical Cancer (Key Biscayne, Florida).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352397"}
{"pmid": "4352398", "title": "Epithelial cell surfaces and the basement membrane in the ocular lens, studied with the scanning electron microscope.", "content": "Epithelial cell surfaces and the basement membrane in the ocular lens, studied with the scanning electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352398"}
{"pmid": "4352399", "title": "Cataracts induced by the polypeptide antibiotic polymyxin B sulfate.", "content": "Cataracts induced by the polypeptide antibiotic polymyxin B sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352399"}
{"pmid": "4352402", "title": "Immunohistochemical demonstration of glucagon in an A 2 -cell carcinoma.", "content": "Immunohistochemical demonstration of glucagon in an A 2 -cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352402"}
{"pmid": "4352403", "title": "Distribution of vitamin D 3 : evidence of accumulation in renal proximal tubuli and thyroid parafollicular cells.", "content": "Distribution of vitamin D 3 : evidence of accumulation in renal proximal tubuli and thyroid parafollicular cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352403"}
{"pmid": "4352401", "title": "Effect of some drugs on the chemotaxis of rabbit neutrophils in vitro.", "content": "Effect of some drugs on the chemotaxis of rabbit neutrophils in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352401"}
{"pmid": "4352404", "title": "Effects of hypophysectomy on lactate metabolism in the perfused rat liver.", "content": "Effects of hypophysectomy on lactate metabolism in the perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352404"}
{"pmid": "4352405", "title": "4-Uloses as intermediates in enzyme-nicotinamide adenine dinucleotide-mediated oxidoreductase mechanisms. I. Uridine diphosphate-galactose-4-epimerase.", "content": "4-Uloses as intermediates in enzyme-nicotinamide adenine dinucleotide-mediated oxidoreductase mechanisms. I. Uridine diphosphate-galactose-4-epimerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352405"}
{"pmid": "4352406", "title": "4-Uloses as intermediates in enzyme-nicotinamide adenine dinucleotide-mediated oxidoreductase mechanisms. II. Regulation of enzymatic activity by reductive inhibition.", "content": "4-Uloses as intermediates in enzyme-nicotinamide adenine dinucleotide-mediated oxidoreductase mechanisms. II. Regulation of enzymatic activity by reductive inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352406"}
{"pmid": "4352408", "title": "The pH dependence of the steady state kinetic parameters for staphylococcal nuclease-catalyzed hydrolysis of deoxythymidine-3'-phosphate-5'-p-nitrophenylphosphate in H 2  O and D 2  O.", "content": "The pH dependence of the steady state kinetic parameters for staphylococcal nuclease-catalyzed hydrolysis of deoxythymidine-3'-phosphate-5'-p-nitrophenylphosphate in H 2  O and D 2  O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352408"}
{"pmid": "4352407", "title": "Further studies of the interaction of cyclic adenosine 3':5'-monophosphate with endometrial protein kinase.", "content": "Further studies of the interaction of cyclic adenosine 3':5'-monophosphate with endometrial protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352407"}
{"pmid": "4352409", "title": "The vasopressin-sensitive adenylate cyclase of the rat renal medulla.", "content": "The vasopressin-sensitive adenylate cyclase of the rat renal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352409"}
{"pmid": "4352410", "title": "Studies on the kinetic mechanism of lipoamide dehydrogenase from rat liver mitochondria.", "content": "Studies on the kinetic mechanism of lipoamide dehydrogenase from rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352410"}
{"pmid": "4352411", "title": "Assembly of the vesicular stomatitis virus envelope: incorporation of viral polypeptides into the host plasma membrane.", "content": "Assembly of the vesicular stomatitis virus envelope: incorporation of viral polypeptides into the host plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352411"}
{"pmid": "4352412", "title": "Transmural gradient of NAD-NADPH ratio in their canine left ventricular myocardium, and effects of coronary dilators on the transmural gradient.", "content": "Transmural gradient of NAD-NADPH ratio in their canine left ventricular myocardium, and effects of coronary dilators on the transmural gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352412"}
{"pmid": "4352414", "title": "Bone cell response to calcium active drugs.", "content": "Bone cell response to calcium active drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352414"}
{"pmid": "4352415", "title": "The influence of psychiatry in medical education.", "content": "The influence of psychiatry in medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352415"}
{"pmid": "4352417", "title": "Streptozotocin-induced lactic acidosis. A case report and some experimental observations.", "content": "Streptozotocin-induced lactic acidosis. A case report and some experimental observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352417"}
{"pmid": "4352416", "title": "Methal-induced granulomatous hypersensitivity in man.", "content": "Methal-induced granulomatous hypersensitivity in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352416"}
{"pmid": "4352418", "title": "A low-temperature EPR study of partially purified, soluble ferric cytochromes P-450 and P-448 from rat liver microsomes.", "content": "A low-temperature EPR study of partially purified, soluble ferric cytochromes P-450 and P-448 from rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352418"}
{"pmid": "4352420", "title": "The use of gel chromatography to study rapid equilibria of the type A + B forms and is formed from C + D.", "content": "The use of gel chromatography to study rapid equilibria of the type A + B forms and is formed from C + D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352420"}
{"pmid": "4352419", "title": "Thermal transitions of proteins.", "content": "Thermal transitions of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352419"}
{"pmid": "4352421", "title": "Effects of preparation method on reversible conformational changes induced by neutral salts in spin-labeled erythrocyte membranes.", "content": "Effects of preparation method on reversible conformational changes induced by neutral salts in spin-labeled erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352421"}
{"pmid": "4352413", "title": "Variable response of renin activity in primary and secondary hypertension.", "content": "Variable response of renin activity in primary and secondary hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352413"}
{"pmid": "4352422", "title": "Proton relaxation rate and fluorometric studies of manganese and rare earth binding to concanavalin A.", "content": "Proton relaxation rate and fluorometric studies of manganese and rare earth binding to concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352422"}
{"pmid": "4352425", "title": "Ultrastructure of rat odontoblasts in various stages of their development and maturation.", "content": "Ultrastructure of rat odontoblasts in various stages of their development and maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352425"}
{"pmid": "4352424", "title": "Observations on the ultrastructure of the buccal epithelium of the rat.", "content": "Observations on the ultrastructure of the buccal epithelium of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352424"}
{"pmid": "4352423", "title": "A comparison of kinetic parameters obtained with three major non-interconvertible isozymes of rat pyruvate kinase.", "content": "A comparison of kinetic parameters obtained with three major non-interconvertible isozymes of rat pyruvate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352423"}
{"pmid": "4352426", "title": "Partial purification and properties of rat liver mitochondrial polynucleotide phosphorylase.", "content": "Partial purification and properties of rat liver mitochondrial polynucleotide phosphorylase. 1. Polynucleotide phosphorylase was partially purified from the inner membrane of rat liver mitochondria. 2. The partially purified particulate enzyme catalyses phosphorolysis of poly(A), poly(C), poly(U) and RNA to nucleoside diphosphates. 3. It is devoid of nucleoside diphosphate-polymerization activity. 4. Variable amounts of ADP/P(i)-exchange activity are associated with the polynucleotide phosphorylase and are probably due to a different enzyme. 5. ADP is the preferred substrate for exchange, and little or no reaction occurs with other nucleoside diphosphates, but ATP/P(i)-exchange takes place at one-third the rate observed with ADP. 6. The partially purified enzyme is free from the phosphatases found in the crude mitochondrial inner membrane, but is associated with an endonuclease activity and some adenylate kinase activity; no cytidylate kinase activity analogous to the latter was detectable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352426"}
{"pmid": "4352427", "title": "Induction of bacterial enzymes.", "content": "Induction of bacterial enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352427"}
{"pmid": "4352428", "title": "Mechanism of action of cortisol in rat liver.", "content": "Mechanism of action of cortisol in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352428"}
{"pmid": "4352429", "title": "Preparation and some properties of a suspension of fragmented tubules from rat kidney.", "content": "Preparation and some properties of a suspension of fragmented tubules from rat kidney. A method is described whereby short fragments of rat kidney tubule were obtained when kidney slices were gently dispersed by exposure to collagenase and hyaluronidase. When suspended in buffered saline the fragmented tubules respired actively over a period of several hours, the rate of oxygen consumption being proportional to the amount of cell protein. Oxygen uptake was stimulated by the addition of glucose, lactate, butyrate, alpha-oxoglutarate and other substrates and was decreased by the omission of Ca(2+) from the suspending medium. With alpha-oxoglutarate as the added substrate, dinitrophenol strongly stimulated oxygen uptake. Dinitrophenol had a less-marked stimulatory effect when glucose was the added substrate, and inhibited respiration in the absence of added substrate. Oligomycin inhibited respiration and this inhibition was partially reversed by dinitrophenol. Fragmented tubules synthesized glucose from lactate at a high rate but this capacity for gluconeogenesis was abolished by dinitrophenol and by physically damaging the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352429"}
{"pmid": "4352430", "title": "Nitrogenase of Klebsiella pneumoniae: electron-paramagnetic-resonance studies on the catalytic mechanism.", "content": "Nitrogenase of Klebsiella pneumoniae: electron-paramagnetic-resonance studies on the catalytic mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352430"}
{"pmid": "4352431", "title": "Regulation of L-serine dehydratase in developing rat liver.", "content": "Regulation of L-serine dehydratase in developing rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352431"}
{"pmid": "4352432", "title": "The induction of ornithine decarboxylase in cultured hepatoma cells.", "content": "The induction of ornithine decarboxylase in cultured hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352432"}
{"pmid": "4352433", "title": "Creatine kinase activity in cultures of differentiating myoblasts.", "content": "Creatine kinase activity in cultures of differentiating myoblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352433"}
{"pmid": "4352434", "title": "The effect of calcium on temperature-induced phase changes in liquid-crystalline cardiolipin structure.", "content": "The effect of calcium on temperature-induced phase changes in liquid-crystalline cardiolipin structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352434"}
{"pmid": "4352435", "title": "Membrane reconstitution in chl-r mutants of Escherichia coli K 12. V. ATPase incorporation into particles formed by complementation.", "content": "Membrane reconstitution in chl-r mutants of Escherichia coli K 12. V. ATPase incorporation into particles formed by complementation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352435"}
{"pmid": "4352436", "title": "B-cell amplification by dibutyryl cyclic AMP in mice.", "content": "B-cell amplification by dibutyryl cyclic AMP in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352436"}
{"pmid": "4352437", "title": "Basic concepts underlying recent developments in the field of Parkinson's disease.", "content": "Basic concepts underlying recent developments in the field of Parkinson's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352437"}
{"pmid": "4352440", "title": "The relationship of rapidly labeled adrenal RNA synthesis to steroidogenesis in a superfusion system: effect of ACTH.", "content": "The relationship of rapidly labeled adrenal RNA synthesis to steroidogenesis in a superfusion system: effect of ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352440"}
{"pmid": "4352442", "title": "Acute effects of altered photoperiods on the onset of ovulation in gonadotropin-treated immature rats.", "content": "Acute effects of altered photoperiods on the onset of ovulation in gonadotropin-treated immature rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352442"}
{"pmid": "4352441", "title": "Endogenous gonadotropin requirements for follicular growth and maintenance in immature rats pretreated with PMS.", "content": "Endogenous gonadotropin requirements for follicular growth and maintenance in immature rats pretreated with PMS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352441"}
{"pmid": "4352443", "title": "Inhibition of adrenocorticotropic hormone production by glucocorticoids in mouse pituitary tumor cells.", "content": "Inhibition of adrenocorticotropic hormone production by glucocorticoids in mouse pituitary tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352443"}
{"pmid": "4352444", "title": "The effect of phenformin on lipolysis and the concentration of cyclic AMP and ATP in white fat cells.", "content": "The effect of phenformin on lipolysis and the concentration of cyclic AMP and ATP in white fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352444"}
{"pmid": "4352445", "title": "Adrenal cells in tissue culture. X. On the mechanism of the stimulation of steroidogenesis by cyclic cytidine monophosphate.", "content": "Adrenal cells in tissue culture. X. On the mechanism of the stimulation of steroidogenesis by cyclic cytidine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352445"}
{"pmid": "4352446", "title": "Interaction of glucagon and catecholamines in the regulation of serine dehydratase.", "content": "Interaction of glucagon and catecholamines in the regulation of serine dehydratase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352446"}
{"pmid": "4352447", "title": "Effects of p-chlorophenoxyisobutyrate (CPIB) on serum insulin levels, insulin sensitivity, and adipose tissue cyclic AMP concentration.", "content": "Effects of p-chlorophenoxyisobutyrate (CPIB) on serum insulin levels, insulin sensitivity, and adipose tissue cyclic AMP concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352447"}
{"pmid": "4352448", "title": "Control of insulin secretion by catecholamines, stress, and the sympathetic nervous system.", "content": "Control of insulin secretion by catecholamines, stress, and the sympathetic nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352448"}
{"pmid": "4352449", "title": "Insulin receptor of liver and fat cell membranes.", "content": "Insulin receptor of liver and fat cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352449"}
{"pmid": "4352450", "title": "The problem of identifying the glucagon receptor.", "content": "The problem of identifying the glucagon receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352450"}
{"pmid": "4352451", "title": "Lipid peroxidation damage to cell components.", "content": "Lipid peroxidation damage to cell components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352451"}
{"pmid": "4352452", "title": "Control of free radical mechanisms in nucleic acid systems: studies in radioprotection and radiosensitization.", "content": "Control of free radical mechanisms in nucleic acid systems: studies in radioprotection and radiosensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352452"}
{"pmid": "4352453", "title": "Falcon Herpesvirus, the etiologic agent of inclusion body disease of falcons.", "content": "Falcon Herpesvirus, the etiologic agent of inclusion body disease of falcons. A viral agent has been isolated from five fatal cases of naturally occurring inclusion body disease in three different falcon species, namely, the prairie falcon (Falco mexicanus), the red-headed falcon (F. chiquera), and the peregrine falcon (F. peregrinus). The virus has been shown to possess the physical, chemical, and biological properties of a herpesvirus and has been used to reproduce inclusion body disease in the prairie falcon, merlin (F. columbarius), and American kestrel (F. sparverius). A similar disease was also produced with this virus in the great horned owl (Bubo virginianus), screech owl (Otus asio), and ring-necked turtle dove (Streptopelia risoria). Serological comparison of the falcon herpesvirus with other known avian herpesviruses revealed that the virus is antigenically closely related to a pigeon herpesvirus and an owl herpesvirus while differing from the former in host range. No antigenic relationship to infectious laryngotracheitis virus, duck virus enteritis, or Marek's disease virus could be demonstrated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352453"}
{"pmid": "4352455", "title": "Surface antigens produced by Herpesviruses Varicella-Zoster virus.", "content": "Surface antigens produced by Herpesviruses Varicella-Zoster virus. Surface antigen(s) was demonstrated by the mixed agglutination technique on cell cultures infected with varicella-zoster virus (V-Z). The reactions appeared to be specific for V-Z, and no cross-reaction was obtained with herpes simplex virus (HSV). V-Z surface antigen had similar physicochemical properties to that of HSV. It was stable to heating at 56 C and treatment with 1% Formalin, 2,4-dinitrophenol, and periodate, whereas it was undetectable after exposure to acetone or ethanol. Antibodies detecting surface antigen were present in high titer in sera from varicella or herpes zoster patients and paralleled titers obtained by the complement fixation test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352455"}
{"pmid": "4352454", "title": "Hemagglutination-inhibition test in rhinovirus infections of volunteers.", "content": "Hemagglutination-inhibition test in rhinovirus infections of volunteers. The hemagglutination-inhibition (HI) test for antirhinovirus antibody was carried out on paired sera from volunteers inoculated with rhinovirus type 3 or type 4 (RV4). The HI test gave results which paralleled the neutralization test and was at least as sensitive as a microneutralization method for detection of serotype-specific antibody. Although high levels of HI antibody in the serum were associated with protection from infection, in the case of RV4 low serum HI antibody levels did not necessarily imply susceptibility to challenge with small doses of virus. HI activity could be measured in concentrated nasal-washing fluids, and this antibody also seemed relevant to protection against infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352454"}
{"pmid": "4352456", "title": "immunoglobulin and histamine-sensitivity response of mice to live Bordetella pertussis.", "content": "immunoglobulin and histamine-sensitivity response of mice to live Bordetella pertussis. Mice injected intranasally (it.n.) and intraperitoneally (i.p.) with a nonlethal dose (2.5 x 10(5) colony-forming units) of live Bordetella pertussis were examined for 50 days for infection, respiratory tract immunoglobulins (Ig), changes in serum Ig, and histamine sensitivity. With mice infected it.n., respiratory infection markedly declined between day 20 and day 30. Ig classes (A, G(1), G(2a), G(2b), but no M), which had specificity for B. pertussis, were present in tracheobronchial wash (TBW) by day 15; by day 50, TBW immunodiffusion and immunoelectrophoretic precipitin bands were more intense. A sharp rise in serum IgA after day 30 was the only significant change relative to controls among the five serum Ig examined. A high degree of histamine sensitivity developed by day 15 to 20 and persisted for the 50 days. With mice inoculated i.p., no bacteria were recovered, no Ig or only traces were found in TBW and IgA only was specific, and no significant changes in the serum Ig relative to controls occurred. Histamine sensitivity developed somewhat more slowly and to a lesser degree than in it.n.-injected mice but persisted for the 50 days. A similar small number of killed bacteria (pertussis vaccine) injected it.n. or i.p. likewise induced slowly developing histamine sensitivity in contrast to published reports of 4 to 5 day peak sensitivity and decline following i.p. injection of 10(9) or more killed bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352456"}
{"pmid": "4352457", "title": "The clinical significance of pituitary-adrenal suppression by exogenous corticosteroids.", "content": "The clinical significance of pituitary-adrenal suppression by exogenous corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352457"}
{"pmid": "4352458", "title": "Hyperlipidemia in coronary heart disease. 3. Evaluation of lipoprotein phenotypes of 156 genetically defined survivors of myocardial infarction.", "content": "Hyperlipidemia in coronary heart disease. 3. Evaluation of lipoprotein phenotypes of 156 genetically defined survivors of myocardial infarction. Although analysis of lipoprotein phenotypes is widely used to diagnose and classify the familial hyperlipidemias, an evaluation of this system as a method for genetic classification has hitherto not been published. The present study of 156 genetically defined survivors of myocardial infarction was therefore designed to examine the relationship between lipoprotein phenotypes and genetic lipid disorders. The lipoprotein phenotypes of each survivor was determined primarily by measurement of his plasma triglyceride and low density lipoprotein (LDL)-cholesterol concentrations; his genetic disorder was identified by analysis of whole plasma cholesterol and triglyceride levels in relatives. The mean levels of LDL-cholesterol discriminated statistically among the three monogenic lipid disorders; it was highest in survivors with familial hypercholesterolemia (261+/-61 mg/100 ml [mean +/-SD]); intermediate in those with familial combined hyperlipidemia (197+/-50); and lowest in those with familial hypertriglyceridemia (155+/-36) (P < 0.005 among the three groups). However, on an individual basis no lipoprotein pattern proved to be specific for any particular genetic lipid disorder; conversely, no genetic disorder was specified by a single lipoprotein pattern. This lack of correlation occurred for the following reasons: (a) individual LDL-cholesterol levels frequently overlapped between disorders; (b) in many instances a small quantitative change in the level of either LDL-cholesterol or whole plasma triglyceride caused qualitative differences in lipoprotein phenotypes, especially in individuals with familial combined hyperlipidemia, who showed variable expression (types IIa, IIb, IV, or V); (c) lipoprotein phenotypes failed to distinguish among monogenic, polygenic, and sporadic forms of hyperlipidemia; (d) clofibrate treatment of some survivors with genetic forms of hyperlipidemia caused their levels of triglyceride and LDL-cholesterol to fall below the 95th percentile, thus resulting in a normal phenotype; and (e) beta-migrating very low density lipoproteins (beta-VLDL), previously considered a specific marker for the type III hyperlipidemic disorder, was identified in several survivors with different lipoprotein characteristics and familial lipid distributions. These studies indicate that lipoprotein phenotypes are not qualitative markers in the genetic sense but instead are quantitative parameters which may vary among different individuals with the same genetic lipid disorder. It would therefore seem likely that a genetic classification of the individual hyperlipidemic patient with coronary heart disease made from a quantitative analysis of lipid levels in his relatives may provide a more meaningful approach than determination of lipoprotein phenotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352458"}
{"pmid": "4352459", "title": "Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man.", "content": "Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man. Hypertriglyceridemic subjects were fed diets in which dietary fat calories were held constant, but carbohydrate calories were varied. Three subjects with fasting chylomicronemia (Type V) were given less carbohydrate and four subjects without fasting chylomicronemia (Type IV) were fed diets with more calories as carbohydrate. The restricted carbohydrate intake led to disappearance of chylomicronemia in those subjects who had chylomicronemia on a normal diet (Type V to IV). In those subjects without chylomicronemia, chylomicronemia appeared in response to increased carbohydrate intake (Type IV to V). Thus chylomicron concentrations in plasma were altered even though fat intake and presumably chylomicron input into plasma was kept constant. These findings provide evidence for saturation of chylomicron removal mechanisms by alteration of endogenous triglyceride-rich lipoprotein concentrations. They suggest that chylomicrons compete with very low density lipoproteins for similar removal mechanisms. The relationship between endogenous triglyceride concentration and the lipolytic activity in plasma following heparin was then evaluated with the use of long-term heparin infusions to release and maintain lipolytic activity in the circulation. 10 subjects were placed on fatfree diets to remove circulating dietary fat. The plasma lipolytic rate during the heparin infusion was measured consecutively on different days in individuals whose triglyceride concentrations were varied by either increasing or decreasing calories. The lipolytic rate was curvilinearly related to the plasma triglyceride concentrations. This curvilinear relationship followed Michaelis-Menton saturation kinetics over a wide range of triglyceride concentrations on fat-free, high-carbohydrate diets, in multiple studies in a group of individuals. These studies suggest that endogenous and exogenous triglyceride compete for a common, saturable, plasma triglyceride removal system related to lipoprotein lipase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352459"}
{"pmid": "4352460", "title": "Identification of inorganic pyrophosphate in human platelets and its release on stimulation with thrombin.", "content": "Identification of inorganic pyrophosphate in human platelets and its release on stimulation with thrombin. Serum inorganic pyrophosphate (PPi) levels were consistently two- to threefold higher than plasma PPi prepared from the same blood. PPi was found in platelets in amounts ranging from 1.4 to 3 nmol/10(8) cells, using three different techniques for quantification. These levels are approximately 800 times higher than the mean PPi concentration in normal plasma and approximate the levels of ADP found in platelets by other workers. About 50% of platelet PPi was specifically released extracellularly after stimulation with thrombin. Timed release experiments showed a pattern of release that resembled that described for ADP and ATP. This pattern was clearly different from that shown by platelet calcium, serotonin, or beta-glucuronidase. Platelet inorganic pyrophosphatase was not released into the supernate in detectable amounts. Platelets from patients with nucleotide storage pool deficiency showed greatly reduced levels of PPi as compared with control. There was no detectable release of PPi into extracellular medium after thrombin addition to a suspension of these platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352460"}
{"pmid": "4352461", "title": "Glucocorticoid-binding proteins in human acute lymphoblastic leukemic blast cells.", "content": "Glucocorticoid-binding proteins in human acute lymphoblastic leukemic blast cells. The first known step in steroid hormone action is the association of the steroid with specific cytoplasmic steroid-binding proteins (SBP). Using a competitive binding assay, we detected, quantified, and partially characterized such a SBP in cytosol from glucocorticoid-sensitive human lymphoblastic leukemic blasts. The affinity of steroids for the SBP was directly related to their known killing potency. For example, steroids without glucocorticoid effect such as androstenedione, etiocholanolone, and tetrahydrocortisol were unable to displace radiolabeled dexamethasone from the SBP in the binding reaction. The dose-response curve for in vitro inhibition of [(3)H]thymidine uptake in leukemic blasts correlated closely with the binding affinity of glucocorticoids to the SBP, providing additional support for an essential physiologic role for SBP in steroid action. SBP activity was either greatly diminished or absent in glucocorticoid-resistant cells. Six patients who intially had SBP in their blasts and were responsive to combinations of drugs including glucocorticoids no longer had SBP activity detectable at a time when they no longer responded to combinations of drugs including glucocorticoids. In vitro [(3)H]thymidine uptake was not inhibited by steroids in leukemic blast cells lacking SBP activity. Other patients who had received some antileukemic therapy including glucocorticoids and who still had SBP in their leukemic blasts, were still responsive to drug combinations that included glucocorticoids. This appears to be the first study demonstrating glucocorticoid receptors in a human tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352461"}
{"pmid": "4352462", "title": "Hemoglobin Abraham Lincoln, beta32 (B14) leucine leads to proline. An unstable variant producing severe hemolytic disease.", "content": "Hemoglobin Abraham Lincoln, beta32 (B14) leucine leads to proline. An unstable variant producing severe hemolytic disease. An unstable hemoglobin variant was identified in a Negro woman with hemolytic anemia since infancy. A splenectomy had been performed when the patient was a child. The anemia was accompanied by erythrocyte inclusion bodies and excretion of darkly pigmented urine. Neither parent of the proposita demonstrated any hematologic abnormality, and it appeared that this hemoglobin variant arose as a new mutation. Erythrocyte survival in the patient was greatly reduced: the erythrocyte t(1/2) using radiochromium as a tag was 2.4 days, and a reticulocyte survival study performed after labeling the cells with L-[(14)C]leucine indicated a t(1/2) of 7.2 days. When stroma-free hemolysates were heated at 50 degrees C, 16-20% of the hemoglobin precipitated. The thermolability was prevented by the addition of hemin, carbon monoxide, or dithionite, suggesting an abnormality of heme binding. An increased rate of methemoglobin formation was also observed after incubation of erythrocytes at 37 degrees C. The abnormal hemoglobin could not be separated from hemoglobin A by electrophoresis or chromatography, but it was possible to isolate the variant beta-chain by precipitation with p-hydroxymercuribenzoate. Purification of the beta-chain by column chromatography followed by peptide mapping and amino acid analysis demonstrated a substitution of proline for beta32 leucine. It appears likely that a major effect of this substitution is a disruption of the normal orientation of the adjacent leucine residue at beta31 to impair heme stabilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352462"}
{"pmid": "4352463", "title": "Biologic and immunologic characterization and physical separation of ACTH and ACTH fragments in the ectopic ACTH syndrome.", "content": "Biologic and immunologic characterization and physical separation of ACTH and ACTH fragments in the ectopic ACTH syndrome. Extracts of tumors from 32 patients with the ectopic ACTH syndrome were subjected to simultaneous bioassay and radioimmunoassays for ACTH. Radioimmunoassays were performed using three antisera, one of which reacts with the extreme N-terminal 1-13 amino acid sequence of ACTH, the second with the N-terminal 1-23 sequence of the ACTH molecule, and the third with the C-terminal 25-39 amino acid sequence of ACTH. There was, in general, good correlation between bioactivity and N-terminal ACTH immunoreactivity. However, there were large excesses of both extreme N-terminal and C-terminal immunoreactive materials in most tumor extracts, which were not found in extracts of three human pituitaries. Three tumor extracts were subjected to molecular sieve chromatography on Sephadex G-50 fine resin. The bioactive ACTH eluted in the same fractions as pituitary ACTH (mol wt approximately 4,500 daltons) and reacted equally in all three ACTH radioimmunoassay systems. The bioactive tumor ACTH was neutralized by incubation with the C-terminal antiserum, indicating it has an intact C-terminal sequence of amino acids. The next several fractions from the Sephadex column contained a material, mol wt approximately 3,100, which was biologically inactive and had C-terminal immunoreactivity but no N-terminal or extreme N-terminal immunoreactivity. Incubation with the N-terminal 1-23 ACTH antiserum did not adsorb these C-terminal fragments, indicating they lacked an intact sequence of amino acids in this region. A smaller ACTH fragment (mol wt approximately 1,800 daltons) eluted in still later fractions and reacted with the extreme N-terminal antiserum but not with the N-terminal or C-terminal antisera. It had no steroidogenic activity, but appeared to have significant melanocyte-stimulating activity. It is concluded that, in addition to an ACTH similar, if not identical, to pituitary ACTH, tumors of patients with the ectopic ACTH syndrome contain both N-terminal and C-terminal ACTH fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352463"}
{"pmid": "4352471", "title": "Cytomegalovirus infection. A case with meningoencephalitis.", "content": "Cytomegalovirus infection. A case with meningoencephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352471"}
{"pmid": "4352465", "title": "Septicaemia due to Pasteurella pneumotropica.", "content": "Septicaemia due to Pasteurella pneumotropica. The literature concerning Pasteurella pneumotropica infection in animals and man is briefly reviewed and a case presented in which the organism was the cause of septicaemia in a patient receiving chemotherapy for myeloid leukaemia. Bacteriological findings are recorded and compared with those of other authors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352465"}
{"pmid": "4352464", "title": "Evidence for complement activation via the alternate pathway in skin diseases, I. Herpes gestationis, systemic lupus erythematosus, and bullous pemphigoid.", "content": "Evidence for complement activation via the alternate pathway in skin diseases, I. Herpes gestationis, systemic lupus erythematosus, and bullous pemphigoid. A patient with herpes gestationis, 6 of 6 patients with bullous pemphigoid, and 5 of 25 patients with systemic lupus erythematosus were found to have properdin deposited along the skin basement membrane.The patient with herpes gestationis demonstrated by immunofluorescence basement membrane deposition of C3 and C5 in the absence of C1q, immunoglobulins, and light chains. A second patient with herpes gestationis had C3 deposition with no demonstrable immunoglobulins or light chains. A thermolabile humoral factor(s) capable of depositing C3 (without C1q or C4) on normal skin basement membrane was found in the sera of both patients with herpes gestationis. No anti-basement membrane antibodies could be demonstrated in the sera of these patients.The patients with systemic lupus erythematosus and bullous pemphigoid who manifested properdin deposition also showed skin basement membrane deposits of C1q, C4, C3, C5, and immunoglobulins. C3 proactivator (C3PA) was also found deposited along the skin basement membrane of three patients with systemic lupus erythematosus and all six bullous pemphigoid patients. This study provides suggestive evidence that activation of complement is occurring via the alternate pathway in herpes gestationis. In systemic lupus erythematosus and bullous pemphigoid, both the classical (antibody) mediated activation of complement as well as the alternate pathway may be operative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352464"}
{"pmid": "4352472", "title": "Malignant pulmonary neoplasms predisposing to spontaneous pneumothorax.", "content": "Malignant pulmonary neoplasms predisposing to spontaneous pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352472"}
{"pmid": "4352473", "title": "In vitro effect of human lymphotoxin on microorganisms.", "content": "In vitro effect of human lymphotoxin on microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352473"}
{"pmid": "4352476", "title": "Electron microscopic detection of simian-type virus particles in human milk.", "content": "Electron microscopic detection of simian-type virus particles in human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352476"}
{"pmid": "4352479", "title": "The effect of intra-arterial contrast media on the small intestine of rabbits. An electron-microscopic study.", "content": "The effect of intra-arterial contrast media on the small intestine of rabbits. An electron-microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352479"}
{"pmid": "4352482", "title": "Biochemical and endocrinological studies in parasite-infested patients with and without infantilism.", "content": "Biochemical and endocrinological studies in parasite-infested patients with and without infantilism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352482"}
{"pmid": "4352481", "title": "Cyclic adenosine monphosphate, metabolites, and phosphorylase in neural tissue: a comparison a methods of fixation.", "content": "Cyclic adenosine monphosphate, metabolites, and phosphorylase in neural tissue: a comparison a methods of fixation. Fixation of rat brain tissue by freeze-blowing, microwave irradiation, immersion of whole rats in liquid nitrogen, and decapitation into liquid nitrogen indicates that postmortem changes in metabolites and enzyme forms are minimal in freeze-blown brains. Cyclic adenosine monophosphate levels are lowest in microwave-irradiated brains, which has been interpreted by some investigators to indicate rapid fixation and minimal anoxia. However, the changes in phosphocreatine, adenosine triphosphate, lactate, and phosphorylase clearly demonstrate that fixation by freeze-blowing or immersion in liquid nitrogen more closely approximate the state in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352481"}
{"pmid": "4352484", "title": "Fungal genetics.", "content": "Fungal genetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352484"}
{"pmid": "4352474", "title": "On the mechanism of antiatherosclerotic agents: microchemical studies on the in vitro effects of pyridinol carbamate and estrogen (premarin) on phosphofructokinase and malate dehydrogenase in the arterial wall.", "content": "On the mechanism of antiatherosclerotic agents: microchemical studies on the in vitro effects of pyridinol carbamate and estrogen (premarin) on phosphofructokinase and malate dehydrogenase in the arterial wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352474"}
{"pmid": "4352477", "title": "Psychophysiological parallels in dreams.", "content": "Psychophysiological parallels in dreams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352477"}
{"pmid": "4352485", "title": "Synthesis and biological activity of some purine 5'-thio-5'-deoxynucleoside 3',5'-cyclic phosphorothioates.", "content": "Synthesis and biological activity of some purine 5'-thio-5'-deoxynucleoside 3',5'-cyclic phosphorothioates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352485"}
{"pmid": "4352486", "title": "Studies on the active-site sulfhydryyl groups of yeast alcohol dehydrogenase.", "content": "Studies on the active-site sulfhydryyl groups of yeast alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352486"}
{"pmid": "4352487", "title": "An interacting spin label study of the fluidizing and condensing effects of cholesterol on lecithin bilayers.", "content": "An interacting spin label study of the fluidizing and condensing effects of cholesterol on lecithin bilayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352487"}
{"pmid": "4352488", "title": "Optical analysis of electron micrographs of cytochrome oxidase membranes.", "content": "Optical analysis of electron micrographs of cytochrome oxidase membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352488"}
{"pmid": "4352489", "title": "Studies on cell-coat macromolecules in normal and virus-transformed BHK 21-C13 cells.", "content": "Studies on cell-coat macromolecules in normal and virus-transformed BHK 21-C13 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352489"}
{"pmid": "4352478", "title": "REM sleep in four-month infants under home and laboratory conditions.", "content": "REM sleep in four-month infants under home and laboratory conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352478"}
{"pmid": "4352490", "title": "Effect of anionic surfactants, nonionic surfactants and neutral salts on the conformation of spin-labeled erythrocyte membrane proteins.", "content": "Effect of anionic surfactants, nonionic surfactants and neutral salts on the conformation of spin-labeled erythrocyte membrane proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352490"}
{"pmid": "4352492", "title": "Characterization of hydrophobic regions in proteins by spin labeling technique.", "content": "Characterization of hydrophobic regions in proteins by spin labeling technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352492"}
{"pmid": "4352493", "title": "The stoichiometry of the paramagnetic copper and the oxidation-reduction potentials of type I copper in human ceruloplasmin.", "content": "The stoichiometry of the paramagnetic copper and the oxidation-reduction potentials of type I copper in human ceruloplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352493"}
{"pmid": "4352491", "title": "The effect of different fatty acid and sterol composition on the erythritol flux through the cell membrane of Acholeplasma laidlawii.", "content": "The effect of different fatty acid and sterol composition on the erythritol flux through the cell membrane of Acholeplasma laidlawii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352491"}
{"pmid": "4352494", "title": "Purification of c-type cytochromes from Nitrosomonas europaea.", "content": "Purification of c-type cytochromes from Nitrosomonas europaea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352494"}
{"pmid": "4352495", "title": "The purification and some properties of the molybdenum-iron protein of Chromatium nitrogenase.", "content": "The purification and some properties of the molybdenum-iron protein of Chromatium nitrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352495"}
{"pmid": "4352496", "title": "Genital herpes simplex virus infection and gonorrhoea. Association and analogies.", "content": "Genital herpes simplex virus infection and gonorrhoea. Association and analogies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352496"}
{"pmid": "4352497", "title": "Plasma renin activity, plasma angiotensin and plasma and urinary electrolytes in normal and toxaemic pregnancy, including a prospective study.", "content": "Plasma renin activity, plasma angiotensin and plasma and urinary electrolytes in normal and toxaemic pregnancy, including a prospective study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352497"}
{"pmid": "4352498", "title": "Vasopressor-induced natriuresis and altered intrarenal haemodynamics in cirrhotic man.", "content": "Vasopressor-induced natriuresis and altered intrarenal haemodynamics in cirrhotic man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352498"}
{"pmid": "4352499", "title": "The measurement of arginine vasopressin in human plasma by radioimmunoassay.", "content": "The measurement of arginine vasopressin in human plasma by radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352499"}
{"pmid": "4352500", "title": "Adipose tissue cellularity and metabolism in newly diagnosed juvenile diabetics.", "content": "Adipose tissue cellularity and metabolism in newly diagnosed juvenile diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352500"}
{"pmid": "4352501", "title": "Interaction of tellurite with the respiratory chain in rat liver mitochondria.", "content": "Interaction of tellurite with the respiratory chain in rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352501"}
{"pmid": "4352502", "title": "Size of the RNA's synthesized by purified calf thymus DNA-dependent RNA polymerases on SV40 DNA.", "content": "Size of the RNA's synthesized by purified calf thymus DNA-dependent RNA polymerases on SV40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352502"}
{"pmid": "4352504", "title": "A study of tRNA methylase action.", "content": "A study of tRNA methylase action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352504"}
{"pmid": "4352503", "title": "The oxidation of acetate by liver mitochondria.", "content": "The oxidation of acetate by liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352503"}
{"pmid": "4352505", "title": "Specific effect of estrogens on an interaction between the uterine estradiol receptor and DNA.", "content": "Specific effect of estrogens on an interaction between the uterine estradiol receptor and DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352505"}
{"pmid": "4352507", "title": "Purification of virus glycoproteins by affinity chromatography using Lens culinaris phytohaemagglutinin.", "content": "Purification of virus glycoproteins by affinity chromatography using Lens culinaris phytohaemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352507"}
{"pmid": "4352506", "title": "Submitochondrial localization of DNA polymerase in rat liver tissue.", "content": "Submitochondrial localization of DNA polymerase in rat liver tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352506"}
{"pmid": "4352508", "title": "Effects of manganese on the activity of glycolytic and gluconeogenic enzymes in the perfused rat liver.", "content": "Effects of manganese on the activity of glycolytic and gluconeogenic enzymes in the perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352508"}
{"pmid": "4352509", "title": "The significance of enzyme histochemical patterns in carcinomas of the large intestine in man.", "content": "The significance of enzyme histochemical patterns in carcinomas of the large intestine in man. The activities of 13 enzymes in 40 carcinomas of the large bowel have been studied using histochemical techniques. Five enzymes-non-specific esterase, monoamine oxidase, succinate dehydrogenase, cytochrome oxidase, and acid phosphatase-commonly show much less activity in the tumours than in adjacent normal colon. The tumours have been classified based upon the number of enzymes which show marked reduction in activity in each tumour (types 1-5). The enzyme histochemical type and the size of the tumours have been jointly correlated with the presence of lymph node metastasis. Small type 1 or 2 tumours do not appear to be associated with metastatic disease. Small type 5 tumours were commonly associated with secondary carcinoma in the lymph nodes. Large tumours (greater than 25 sq cm surface area) of any histochemical type were frequently associated with lymph node metastasis. Discussion of the possible reasons for these findings and their clinical significance is presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352509"}
{"pmid": "4352511", "title": "E.P.R. of free radicals formed in DNA and its constituents after exposure to discharge-excited inert gases. II. Purines and DNA.", "content": "E.P.R. of free radicals formed in DNA and its constituents after exposure to discharge-excited inert gases. II. Purines and DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352511"}
{"pmid": "4352512", "title": "Dysphagia, vomiting and obdurate constipation as a metabolic manifestation of malignancy.", "content": "Dysphagia, vomiting and obdurate constipation as a metabolic manifestation of malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352512"}
{"pmid": "4352513", "title": "Water-soluble and pentanol-extractable proteins in human brain normal tissue and human brain tumours, with special reference to S-100 protein.", "content": "Water-soluble and pentanol-extractable proteins in human brain normal tissue and human brain tumours, with special reference to S-100 protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352513"}
{"pmid": "4352515", "title": "Myelin subfractions in developing rat brain: characterization and sulphatide metabolism.", "content": "Myelin subfractions in developing rat brain: characterization and sulphatide metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352515"}
{"pmid": "4352514", "title": "The effect of ionizing radiation upon mitochondria of the central nervous system.", "content": "The effect of ionizing radiation upon mitochondria of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352514"}
{"pmid": "4352517", "title": "Mitochondrial cytochrome oxidase and monoamine oxidase activities in the developing chick cerebral hemispheres.", "content": "Mitochondrial cytochrome oxidase and monoamine oxidase activities in the developing chick cerebral hemispheres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352517"}
{"pmid": "4352516", "title": "The occurrence of a glycine cleavage system in mammalian brain.", "content": "The occurrence of a glycine cleavage system in mammalian brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352516"}
{"pmid": "4352518", "title": "Availability to neuraminidase of gangliosides and sialoglycoproteins in neuronal membranes.", "content": "Availability to neuraminidase of gangliosides and sialoglycoproteins in neuronal membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352518"}
{"pmid": "4352522", "title": "Electron microscopic identification of papova virus in laryngeal papilloma.", "content": "Electron microscopic identification of papova virus in laryngeal papilloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352522"}
{"pmid": "4352525", "title": "Bicuculline, GABA and central inhibition.", "content": "Bicuculline, GABA and central inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352525"}
{"pmid": "4352526", "title": "Infantile polymyoclonia.", "content": "Infantile polymyoclonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352526"}
{"pmid": "4352527", "title": "Hyperkalaemic periodic paralysis associated with Addison's disease.", "content": "Hyperkalaemic periodic paralysis associated with Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352527"}
{"pmid": "4352528", "title": "Dysaesthesia-dyskinesia: a syndrome of painful legs and moving toes.", "content": "Dysaesthesia-dyskinesia: a syndrome of painful legs and moving toes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352528"}
{"pmid": "4352529", "title": "Spontaneous regression of leukemia in chickens infected with avian myeloblastosis virus.", "content": "Spontaneous regression of leukemia in chickens infected with avian myeloblastosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352529"}
{"pmid": "4352530", "title": "Isolated pituitary cells: CRF-like activity of neurohypophysial and related polypeptides.", "content": "Isolated pituitary cells: CRF-like activity of neurohypophysial and related polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352530"}
{"pmid": "4352531", "title": "Calcification of a lysozyme-inositol phosphatide complex in vitro.", "content": "Calcification of a lysozyme-inositol phosphatide complex in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352531"}
{"pmid": "4352533", "title": "Suppression of established Friend virus leukemia by statolon. VII. Relative roles of interferon and the immune response in development of FV-dormant infections.", "content": "Suppression of established Friend virus leukemia by statolon. VII. Relative roles of interferon and the immune response in development of FV-dormant infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352533"}
{"pmid": "4352532", "title": "The effect of riboflavin deficiency on key gluconeogenic enzyme activities in rat liver.", "content": "The effect of riboflavin deficiency on key gluconeogenic enzyme activities in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352532"}
{"pmid": "4352534", "title": "Enhanced growth of a polyoma transformed tumor cell in Spirometra mansonoides-infected hamsters.", "content": "Enhanced growth of a polyoma transformed tumor cell in Spirometra mansonoides-infected hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352534"}
{"pmid": "4352535", "title": "Further studies of viral antibodies in the cerebrospinal fluid of patients with multiple sclerosis: vaccinia and parainfluenza type 1.", "content": "Further studies of viral antibodies in the cerebrospinal fluid of patients with multiple sclerosis: vaccinia and parainfluenza type 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352535"}
{"pmid": "4352536", "title": "Propagation of Rauscher leukemia virus to human lymphoblastoid cells by in vivo diffusion chamber cultivation.", "content": "Propagation of Rauscher leukemia virus to human lymphoblastoid cells by in vivo diffusion chamber cultivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352536"}
{"pmid": "4352537", "title": "The effect of LATS and TSH on protein and RNA synthesis in isolated thyroid cells.", "content": "The effect of LATS and TSH on protein and RNA synthesis in isolated thyroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352537"}
{"pmid": "4352538", "title": "Body movements during sleep after sleep loss.", "content": "Body movements during sleep after sleep loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352538"}
{"pmid": "4352541", "title": "DNA polymerases in RNA tumor viruses and possible \"protoviruses\".", "content": "DNA polymerases in RNA tumor viruses and possible \"protoviruses\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352541"}
{"pmid": "4352540", "title": "Trans-sphenoidal surgery for pituitary lesions.", "content": "Trans-sphenoidal surgery for pituitary lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352540"}
{"pmid": "4352542", "title": "The presence and expression of RNA tumor virus genes in normal and infected cells: detection by molecular hybridization.", "content": "The presence and expression of RNA tumor virus genes in normal and infected cells: detection by molecular hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352542"}
{"pmid": "4352543", "title": "Introductory review. Molecular mechanisms in viral neoplasia of animals and their implications in the origin of cancer in man.", "content": "Introductory review. Molecular mechanisms in viral neoplasia of animals and their implications in the origin of cancer in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352543"}
{"pmid": "4352545", "title": "Evidence for 30-40S RNA as precursor of the 60-70S RNA of Rous sarcoma virus.", "content": "Evidence for 30-40S RNA as precursor of the 60-70S RNA of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352545"}
{"pmid": "4352544", "title": "Evidence for viral involvement in murine and human mammary adenocarcinoma.", "content": "Evidence for viral involvement in murine and human mammary adenocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352544"}
{"pmid": "4352546", "title": "Molecular evidence for a viral etiology of human leukemias, lymphomas, and sarcomas.", "content": "Molecular evidence for a viral etiology of human leukemias, lymphomas, and sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352546"}
{"pmid": "4352548", "title": "Animal model of human disease: primary hepatocellular carcinoma.", "content": "Animal model of human disease: primary hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352548"}
{"pmid": "4352547", "title": "Molecular probes in studies of the relationship of viruses to human neoplasia.", "content": "Molecular probes in studies of the relationship of viruses to human neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352547"}
{"pmid": "4352549", "title": "Interaction of angiotensin with disseminated intravascular coagulation: a possible mechanism in the genesis of acute renal failure.", "content": "Interaction of angiotensin with disseminated intravascular coagulation: a possible mechanism in the genesis of acute renal failure. Because of the importance of the renin-angiotensin system in renal homeostatic mechanisms, the effect of angiotensin administration upon disseminated intravascular coagulation has been studied in rabbits. An infusion of angiotensin II (0.1 mug/kg/min for 2 hours) produced neither histologic abnormalities in the kidneys nor an elevation of creatinine. After an infusion of thrombin (2.0 units/kg/min for 2 hours) only 3 of 10 rabbits, when sacrified 24 hours later, showed histologic lesions comprised of occasional fibrin thrombi and foci of tubular necrosis. Creatinine levels did not rise. In contrast, the combination of angiotensin and thrombin resulted in renal lesions in 12 of 14 animals. Four had frank cortical necrosis, while combinations of tubular necrosis, glomerular thrombosis and segmental glomerular infarction occurred in the others, together with elevated creatinine levels. Blockade of alpha-adrenoreceptors with phenoxybenzamine in 12 animals did not prevent either these histologic changes or creatinine elevation, showing that the effect of angiotensin was independent of alpha-adrenoreceptor stimulation. The synergistic interaction between angiotensin and disseminated intravascular coagulation was not explained by differences in the consumption of plasma fibrinogen but apparently was due to localization of fibrin thrombi within glomerular capillaries by the vasomotor actions of angiotensin, as has previously been shown to occur with alpha-adrenoreceptor simulation. Such a mechanism might contribute to renal glomerular deposition of fibrin in acute ischemic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352549"}
{"pmid": "4352550", "title": "Gastrontestinal cytomegalovirus infection.", "content": "Gastrontestinal cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352550"}
{"pmid": "4352551", "title": "Duodenal wall tumors and the Zollinger-Ellison syndrome. Surgical management.", "content": "Duodenal wall tumors and the Zollinger-Ellison syndrome. Surgical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352551"}
{"pmid": "4352552", "title": "A soluble CO-binding c-type cytochrome from the marine bacterium Beneckea natriegens.", "content": "A soluble CO-binding c-type cytochrome from the marine bacterium Beneckea natriegens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352552"}
{"pmid": "4352553", "title": "Biochemical and biophysical studies on cytochrome c oxidase. X. Spectral and potentiometric properties of the hemes and coppers.", "content": "Biochemical and biophysical studies on cytochrome c oxidase. X. Spectral and potentiometric properties of the hemes and coppers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352553"}
{"pmid": "4352539", "title": "Carotid body chemodectomas: recent experience at University of Alabama hospitals.", "content": "Carotid body chemodectomas: recent experience at University of Alabama hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352539"}
{"pmid": "4352555", "title": "Inhibition of 5 -reductase activity of rat prostate by estradiol derivatives.", "content": "Inhibition of 5 -reductase activity of rat prostate by estradiol derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352555"}
{"pmid": "4352575", "title": "The pneumonocytes in the lung of Xenopus laevis.", "content": "The pneumonocytes in the lung of Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352575"}
{"pmid": "4352576", "title": "Measurement of inorganic pyrophosphate in biological fluids. Elevated levels in some patients with osteoarthritis, pseudogout, acromegaly, and uremia.", "content": "Measurement of inorganic pyrophosphate in biological fluids. Elevated levels in some patients with osteoarthritis, pseudogout, acromegaly, and uremia. A rapid and relatively simple method for measurement of inorganic pyrophosphate (PPi) in biological samples has been described. The mean +/-SEM of plasma samples from 94 normal subjects was 1.8+/-0.06 muM, giving a normal range (99% confidence limits) of 0.16 - 3.40 mumol/liter. Analysis of 17 plasma samples in duplicate showed a standard deviation of 0.18, giving a 99% probability that a single determination of plasma PPi would be +/-0.68 muM of the true value. The mean PPi levels in plasma from subjects with osteoarthritis, pseudogout, acromegaly, and uremia were significantly greater than the normal mean (P < 0.01). Samples from rheumatoid arthritis showed PPi levels distributed about a mean identical to the normal mean. Plasma inorganic orthophosphate levels correlated positively with PPi levels in samples from normal subjects and in samples from patients with osteoarthritis, pseudogout, and uremia, but not with acromegaly. This correlation was statistically significant only in the normal samples and in those from patients with osteoarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352576"}
{"pmid": "4352577", "title": "Simulation of tissue properties in irreversible diffuse obstructive pulmonary syndromes. Enzyme digestion.", "content": "Simulation of tissue properties in irreversible diffuse obstructive pulmonary syndromes. Enzyme digestion. The length-tension properties of alveolar wall from normal cats were studied before and after exposure to enzymes naturally found in mammals (elastase, trypsin, collagenase, hyaluronidase). Hyaluronidase effected little change while all the proteolytic enzymes altered the mechanical properties of lung tissue. Collagenase removed the \"mechanical stop\" and the alveolar walls fractured at low forces. The properties of wall exposed to trypsin resembled those of elastase-treated tissue. Elastase increased the extension necessary to reach a given force and increased the maximum length (L(max)) and resting length (L(o)). Maximum extensibility (lambda(max)), the ratio of L(max) to L(o), fell with both elastase and trypsin digestion. A reduction in lambda(max) simulates the changes in alveolar wall properties seen in the lungs of the aged and in those with an irreversible diffuse obstructive pulmonary syndrome (DOPS(I)). Unlike these states, however, the energy loss in stretching alveolar wall increased with elastolysis. Furthermore, the changes in L(o) necessary to effect a change in lambda(max) of alveolar wall comparable to that seen in DOPS(I) were excessive. The altered tissue properties that occur in man with obstructive pulmonary syndromes could not be produced with these proteolytic enzymes or with hyaluronidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352577"}
{"pmid": "4352578", "title": "Regulation of adrenal ornithine decarboxylase by adrenocorticotropic hormone and cyclic AMP.", "content": "Regulation of adrenal ornithine decarboxylase by adrenocorticotropic hormone and cyclic AMP. Adrenal ornithine decarboxylase activity was stimulated in a dose-related manner after administration of ACTH or dibutyryl ((6)N-2'-O-dibutyryl) cyclic AMP to hypophysectomized rats. Little effect was observed for 2 h, but striking increases in enzyme activity were observed 4 h after administration of these substances. Effects of ACTH and dibutyryl cyclic AMP were not secondary to stimulation of steroidogenesis, since hydrocortisone had no effect on adrenal ornithine decarboxylase although it did stimulate activity of the enzyme in the liver and kidney.ACTH, given subcutaneously to hypophysectomized rats, induced striking increases in adrenal cyclic AMP levels within 15-30 min with a fall towards the base line in 1 h. Increases in ornithine decarboxylase activity lag several hours after this endogenous cyclic AMP peak, in contrast to the stimulatin of steroidogenesis by the nucleotide that requires only 2-3 min. After graded doses of ACTH, increases in adrenal cyclic AMP levels at 30 min were paralleled by proportional increases in adrenal ornithine decarboxylase activity 4 h after hormone treatment. Whereas maximal levels of adrenal steroidogenesis have been observed at tissue cyclic AMP levels of 6 nmol/g. ACTH is capable of inducing increases in nucleotide levels up to 200 nmol/g or more. These high tissue levels of cyclic AMP, although unneccessary for maximal steroidogenesis, appear to stimulate adrenal ornithine decarboxylase activity. Several results in addition to the time lag in the stimulation of ornithine decarboxylase activity suggest a mechanism involving accumulation of the enzyme or some factor needed for its activity rather than direct activation of the enzyme by cyclic AMP. Thus, the addition of cyclic AMP directly to the ornithine decarboxylase assay mixture in vitro was without stimulatory effect. In addition, actinomycin D or cycloheximide in doses sufficient to block adrenal RNA and protein synthesis, respectively inhibited the stimulation of ornithine decarboxylase activity by ACTH in vivo. An adrenocortical cancer was found to maintain ornithine decarboxylase activity at very high levels, but did so at much lower cyclic AMP levels than those of ACTH-stimulated adrenals. It is concluded that ACTH stimulates adrenal ornithine decarboxylase activity and that this effect may be mediated by cyclic AMP. However, cyclic AMP be mediated by appear to be a determinant of the high level of enzyme activity found in adrenocortical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352578"}
{"pmid": "4352579", "title": "Development of intestinal adenyl cyclase and its response to cholera enterotoxin.", "content": "Development of intestinal adenyl cyclase and its response to cholera enterotoxin. Adenyl cyclase activity in intestinal membranes has been studied during development in the rabbit fetus from fetal day 17 to 10 days postnatally and in the human fetus from the 10th to the 17th wk of gestation. In the rabbit, the enzyme was already present by fetal day 17 and showed a fourfold peak rise in specific activity by 22 days. By 28 days, the specific activity had fallen toward adult levels and remained constant throughout gestation and the 1st wk of life. Fluoridestimulated activity showed a similar curve, and was 2.5-5 times the basal values. Activities in jejunum and ileum were comparable at all time points studied. Phosphodiesterase activity did not change during gestation. When fetal intestinal segments were incubated in vitro with purified cholera enterotoxin, adenyl cyclase activity in subsequently prepared membranes was increased two- to threefold. This level was not regularly further elevated by fluoride ion. Lithium ion inhibited both the basal and fluoride-stimulated enzyme activity in membranes prepared from rabbit fetuses at term. Lactase activity (reflecting the development of the microvilli) in either whole intestinal homogenates or in the membrane fractions showed a differnet pattern of development, with a rise beginning on fetal day 24 and a plateau just after birth. In intestinal membranes prepared from human fetuses, the activity of both basal and fluoride-stimulated adenyl cyclase tripled from the 10th to the 17th wk of gestation. The data both in the rabbit and in man show that intestinal adenyl cyclase is capable of responding to cholera enterotoxin quite early in gestation. In the rabbit, this occurs before the time of appearance or ville or of an enzyme marker (lactase) for microville. The results support the concept that adenyl cyclase is present in plasma membrane other than the brush border.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352579"}
{"pmid": "4352580", "title": "Disparate enzyme activity in erythocytes and leukocytes. A variant of hypoxanthine phosphoribosyl-transferase deficiency with an unstable enzyme.", "content": "Disparate enzyme activity in erythocytes and leukocytes. A variant of hypoxanthine phosphoribosyl-transferase deficiency with an unstable enzyme. A family is reported in which each of two sisters has a son with no detectable hypoxanthine phosphoribosyltransferase (HPRT) (EC 2. 4. 2. 8) in his erythrocytes, a finding considered pathognomonic of Lesch-Nyhan disease. However, neither has the stigmata of the disease. One boy is neurologically normal, and the other is moderately retarded. There was only a slight increase in urinary uric acid, but the amounts of hypoxanthine and xanthine, and their ratios, were similar to those found in Lesch-Nyhan disease, strongly indicating that excesses of these last two oxypurines are not responsible for the symptomatology in that disease. In contrast to the nondetectable HPRT activity in the red blood cells, leukocyte lysates from the two boys have 10-15% of normal activity, possibly reflecting continuing synthesis of an unstable enzyme. This hypothesis is supported by the demonstration that at 4 degrees C HPRT activity was rapidly lost in the propositus while the activity increased in control subjects. The mother's cells were intermediate between the two. The intact and disrupted leukocytes of the hemizygote, in the absence of added phosphoribosyl converted as much hypoxanthine to inosinate as the normal cell, and appropriate tests indicated that under these circumstances enzyme concentration is not rate limiting whereas the concentration of the cosubstrate, phosphoribosyl pyrophosphate, is. The capacity for normal function in the intact mutant cell is more representative of in vivo conditions than the lysate, which may explain the important modification of clinical symptomatology, the relatively mild hyperuricosuria, and the presence of mosaicism in the circulating blood cells of the heterozygotes. A similar explanation may apply to other genetic diseases in which incomplete but severe enzyme deficiencies are found in clinically normal individuals. An associated deficiency in glucose-6-phosphate dehydrogenase in this family permitted confirmation of previous observations on linkage with hypoxanthine phosphoribosyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352580"}
{"pmid": "4352583", "title": "Mutants of nonproducer cell lines transformed by murine sarcoma viruses. I. Induction, isolation, particle production, and tumorigenicity.", "content": "Mutants of nonproducer cell lines transformed by murine sarcoma viruses. I. Induction, isolation, particle production, and tumorigenicity. A variety of cell mutants were obtained by a single 5'-bromodeoxyuridine (BrdU) treatment of an nonproducer (NP) cell line transformed by the Kirsten strain of murine sarcoma virus (Ki-MSV). Isolation procedures of these cell See PDF for Structure mutants are described. The cell mutants obtained were classified by tumorigenic potential and shedding of Type C virus particles. The cell mutants were classified into four groups: (A) tumorigenic, without particles; (B) tumorigenic, with Type C particles; (C) nontumorigenic, without particles; and (D) nontumorigenic, with Type C particles. The tumorigenic cell lines showed variability in morphology with both flat and typical transformed appearing cell lines showing equal transplantability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352583"}
{"pmid": "4352584", "title": "The modulating influence of cyclic nucleotides upon lymphocyte-mediated cytotoxicity.", "content": "The modulating influence of cyclic nucleotides upon lymphocyte-mediated cytotoxicity. The capacity of allosensitized thymus-derived lymphocytes to destroy target cells bearing donor alloantigens is modulated by the cellular levels of cyclic AMP and cyclic GMP. Increases in the cyclic AMP levels of attacking lymphocytes by stimulation with prostaglandin E(1), isoproterenol, and cholera toxin inhibit lymphocyte-mediated cytotoxicity; whereas, depletion of cyclic AMP with imidazole enhances cytotoxicity. The augmentation of cytotoxicity produced by cholinergic stimulation with carbamylcholine is not associated with alterations in cyclic AMP levels and is duplicated by 8-bromo-cyclic GMP. The effects of activators of adenylate cyclase, cholinomimetic agents, and 8-bromocyclic GMP are upon the attacking and not the target cells and occur at the time of initial interaction of attacking and target cells. Indeed, the level of cyclic nucleotide (cyclic AMP and cyclic GMP) at the time of initial cell-to-cell interaction determines the extent of cytotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352584"}
{"pmid": "4352585", "title": "Observations on the microbiological flora of canned Parma ham.", "content": "Observations on the microbiological flora of canned Parma ham. A significant proportion of a consignment of branded Parma Ham was found to have ;blown' tins; the associated bacterial flora was therefore investigated. No Salmonella or Shigella were found. Clostridium welchii type A and Clostridium bifermentans were isolated in moderate numbers only from enrichment cultures of the ham. Staphylococcus spp. and coryneform bacteria were obtained from all tins and Group D streptococci were present in a few. No food-poisoning cases were associated with this ham.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352585"}
{"pmid": "4352586", "title": "Lipid A: chemical structure and biological activity.", "content": "Lipid A: chemical structure and biological activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352586"}
{"pmid": "4352587", "title": "Immunologic and antineoplastic effects of endotoxin: role of membranes and mediation by cyclic adenosine-3',5'-monophosphate.", "content": "Immunologic and antineoplastic effects of endotoxin: role of membranes and mediation by cyclic adenosine-3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352587"}
{"pmid": "4352582", "title": "Petrographic study of the refractory performance of high-fusing dental alloy investments. II. Silica-bonded investments.", "content": "Petrographic study of the refractory performance of high-fusing dental alloy investments. II. Silica-bonded investments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352582"}
{"pmid": "4352589", "title": "Radiotherapy of glioblastoma multiforme.", "content": "Radiotherapy of glioblastoma multiforme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352589"}
{"pmid": "4352581", "title": "An experimental radiopaque composite material.", "content": "An experimental radiopaque composite material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352581"}
{"pmid": "4352588", "title": "Effects of endotoxin on macrophages and other lymphoreticular cells.", "content": "Effects of endotoxin on macrophages and other lymphoreticular cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352588"}
{"pmid": "4352590", "title": "Intravenous radionuclide hepatography in the differential diagnosis of intrahepatic mass lesions.", "content": "Intravenous radionuclide hepatography in the differential diagnosis of intrahepatic mass lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352590"}
{"pmid": "4352591", "title": "Evaluation of vitamin D supplements by biological assay using the turkey.", "content": "Evaluation of vitamin D supplements by biological assay using the turkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352591"}
{"pmid": "4352592", "title": "The in-vitro effects of silica-treated hamster macrophages on collagen production by hamster fibroblasts.", "content": "The in-vitro effects of silica-treated hamster macrophages on collagen production by hamster fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352592"}
{"pmid": "4352593", "title": "Triple carcinoma of the breast, one arising within a fibro-adenoma.", "content": "Triple carcinoma of the breast, one arising within a fibro-adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352593"}
{"pmid": "4352594", "title": "Androblastoma of the ovary with heterotopic elements.", "content": "Androblastoma of the ovary with heterotopic elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352594"}
{"pmid": "4352595", "title": "Lactic dehydrogenase and other enzymes in the mouse uterus during the peri-implantation period of pregnancy.", "content": "Lactic dehydrogenase and other enzymes in the mouse uterus during the peri-implantation period of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352595"}
{"pmid": "4352597", "title": "Conservative management of the infected pacemaker pulse generator.", "content": "Conservative management of the infected pacemaker pulse generator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352597"}
{"pmid": "4352596", "title": "Secretion and uptake of peroxidase by rat adenohypophyseal cells.", "content": "Secretion and uptake of peroxidase by rat adenohypophyseal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352596"}
{"pmid": "4352598", "title": "Studies of the myocardial metabolism of free radicals in the myocardial infarction (with electron spin resonance (ESR) spectrometry).", "content": "Studies of the myocardial metabolism of free radicals in the myocardial infarction (with electron spin resonance (ESR) spectrometry).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352598"}
{"pmid": "4352601", "title": "Delayed dermal hypersensitivity to autologous lymphocytes in multiple sclerosis.", "content": "Delayed dermal hypersensitivity to autologous lymphocytes in multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352601"}
{"pmid": "4352603", "title": "Nervous system lesions after sting by yellow jacket. A case report.", "content": "Nervous system lesions after sting by yellow jacket. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352603"}
{"pmid": "4352602", "title": "Myasthenia gravis lacking response to cholinergic drugs.", "content": "Myasthenia gravis lacking response to cholinergic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352602"}
{"pmid": "4352609", "title": "Vasopressin: possible role of microtubules and microfilaments in its action.", "content": "Vasopressin: possible role of microtubules and microfilaments in its action. Colchicine, vinblastine, podophyllotoxin, and cytochalasin B inhibit the action of vasopressin and cyclic adenosine monophosphate on osmotic water movement across the toad bladder. The findings suggest that microtubules, and possibly microfilaments, play a role in the action of vasopressin, perhaps through involvement in the mechanism of release of secretory material from the bladder epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352609"}
{"pmid": "4352611", "title": "Poliomyelitis vaccination of infants: preimmunization status and seroconversion.", "content": "Poliomyelitis vaccination of infants: preimmunization status and seroconversion. A study was carried out in Delhi on the preimmunization status of infants aged 2-6 months with regard to poliomyelitis and on seroconversion after the administration of oral poliomyelitis vaccine. It was found that 30.3% of the 204 infants included in the study excreted enteroviruses, 58% of which were found to be polioviruses. Of 197 sera examined for neutralizing antibodies against different types of poliovirus, 73% were found to be triple negative and only 4.0% triple positive. Three doses of oral poliomyelitis vaccine were administered at intervals of 1 month. It was found that 71.8% of the vaccinated infants excreted cytopathogenic agents in the 7 days following the first dose; 80.4% of these agents were found to be polioviruses. Seroconversion was studied in 71 infants, and good antibody responses to all three types of poliovirus were observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352611"}
{"pmid": "4352612", "title": "The second international reference preparation of viomycin.", "content": "The second international reference preparation of viomycin. The first International Reference Preparation of Viomycin was replaced by the second international reference preparation, consisting of material from the batch that provided the second Working Standard of the US Food and Drug Administration. The International Unit of viomycin was redefined as the activity contained in 0.0012285 mg of the second international reference preparation. Examination of batches of viomycin sulfate from the various sources of production showed that the second international reference preparation was suitable for their assay, whereas a sample previously proposed as the international standard of viomycin was unsatisfactory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352612"}
{"pmid": "4352613", "title": "Pyruvate carboxylase in the developing chick embryo.", "content": "Pyruvate carboxylase in the developing chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352613"}
{"pmid": "4352619", "title": "Effect of pentagastrin on adult rat duodenal cells in culture.", "content": "Effect of pentagastrin on adult rat duodenal cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352619"}
{"pmid": "4352620", "title": "Hepatic changes in adult alpha-1-antitrypsin deficiency.", "content": "Hepatic changes in adult alpha-1-antitrypsin deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352620"}
{"pmid": "4352622", "title": "Induction of tryptophan oxygenase in Cicer arietinum seedlings by indole-3-acetic acid & cyclic 3',5'-adenosine monophosphate.", "content": "Induction of tryptophan oxygenase in Cicer arietinum seedlings by indole-3-acetic acid & cyclic 3',5'-adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352622"}
{"pmid": "4352614", "title": "Causes and prevention of colonic anastomotic breakdown.", "content": "Causes and prevention of colonic anastomotic breakdown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352614"}
{"pmid": "4352623", "title": "Mechanisms of inhibition and activation of beef liver D-glycerate dehydrogenase by inorganic anions.", "content": "Mechanisms of inhibition and activation of beef liver D-glycerate dehydrogenase by inorganic anions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352623"}
{"pmid": "4352624", "title": "Kinetic studies on the G-factor-dependent uncoupled GTPase of ribosomes.", "content": "Kinetic studies on the G-factor-dependent uncoupled GTPase of ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352624"}
{"pmid": "4352625", "title": "Isolation and characterization of glycopeptides from rat liver nuclear membrane.", "content": "Isolation and characterization of glycopeptides from rat liver nuclear membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352625"}
{"pmid": "4352626", "title": "Purification and some properties of G-factor from the silk gland of silkworm.", "content": "Purification and some properties of G-factor from the silk gland of silkworm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352626"}
{"pmid": "4352627", "title": "Effect of calcium ion on lipase-fat complex formation.", "content": "Effect of calcium ion on lipase-fat complex formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352627"}
{"pmid": "4352628", "title": "Studies on proteolytic enzymes (pronase) of Streptomyces griseus K-1. 3. Purification and proteolytic specificity of alkaline proteinase C from pronase.", "content": "Studies on proteolytic enzymes (pronase) of Streptomyces griseus K-1. 3. Purification and proteolytic specificity of alkaline proteinase C from pronase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352628"}
{"pmid": "4352629", "title": "DNA dependent RNA polymerase from Ehrlich ascites tumor cells. II. Factors stimulating the activity of RNA polymerase II.", "content": "DNA dependent RNA polymerase from Ehrlich ascites tumor cells. II. Factors stimulating the activity of RNA polymerase II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352629"}
{"pmid": "4352630", "title": "Serum thyrotropin (TSH) in pituitary and-or hypothalamic hypothyroidism: normal or elevated basal levels and paradoxical responses to thyrotropin-releasing hormone.", "content": "Serum thyrotropin (TSH) in pituitary and-or hypothalamic hypothyroidism: normal or elevated basal levels and paradoxical responses to thyrotropin-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352630"}
{"pmid": "4352631", "title": "Oat-cell carcinoma of the lung simultaneously producing ACTH and serotonin.", "content": "Oat-cell carcinoma of the lung simultaneously producing ACTH and serotonin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352631"}
{"pmid": "4352615", "title": "Adenocarcinoma of the colon associated with ureterosigmoidostomy: report of a case.", "content": "Adenocarcinoma of the colon associated with ureterosigmoidostomy: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352615"}
{"pmid": "4352632", "title": "Maternal-fetal ACTH relationship in man.", "content": "Maternal-fetal ACTH relationship in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352632"}
{"pmid": "4352633", "title": "Radioreceptor assay for growth hormone.", "content": "Radioreceptor assay for growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352633"}
{"pmid": "4352639", "title": "Catecholamine transmitter for salivary secretion in the cockroach.", "content": "Catecholamine transmitter for salivary secretion in the cockroach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352639"}
{"pmid": "4352640", "title": "Neoplasm induction by murine type-C viruses passaged directly from spontaneous non-lymphoreticular tumours.", "content": "Neoplasm induction by murine type-C viruses passaged directly from spontaneous non-lymphoreticular tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352640"}
{"pmid": "4352641", "title": "Gonadotropin and steroid hormone excretion in trophoblastic neoplasia.", "content": "Gonadotropin and steroid hormone excretion in trophoblastic neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352641"}
{"pmid": "4352642", "title": "Spontaneous regression of Bowenoid atypia of the vulva.", "content": "Spontaneous regression of Bowenoid atypia of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352642"}
{"pmid": "4352643", "title": "Metastatic and secondary tumors of the vulva.", "content": "Metastatic and secondary tumors of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352643"}
{"pmid": "4352644", "title": "A comparative evaluation of the distribution of concanavalin A-binding sites on the surfaces of normal, virally-transformed, and protease-treated fibroblasts.", "content": "A comparative evaluation of the distribution of concanavalin A-binding sites on the surfaces of normal, virally-transformed, and protease-treated fibroblasts. The topographical distributions of concanavalin A-binding sites on the surfaces of 3T3, proteasetreated 3T3, and simian virus 40-transformed 3T3 cultured mouse fibroblasts appear to be different, as shown by a shadow-cast replica technique using concanavalin A and a hemocyanin marker, or as shown previously on isolated membranes with concanavalin A coupled to ferritin. However, chemical fixation of cells before labeling with concanavalin A and hemocyanin, or labeling exclusively at 4 degrees , allows one to distinguish between inherent concanavalin A-binding-site topography and potential rearrangement of sites induced by the action of the multivalent concanavalin A molecule itself. The inherent distribution of binding sites on 3T3, protease-treated 3T3, and transformed cells is actually the same on all cells, i.e., dispersed and random. Treatment of unfixed transformed or protease-treated 3T3 cells, but not normal 3T3 cells, with concanavalin A and hemocyanin at 37 degrees (or at 4 degrees with subsequent warming to 37 degrees ), however, results in clustering of binding sites, presumably due to crosslinking of neighboring lectin-binding sites by the quadrivalent concanavalin A. Thus, the underlying difference between concanavalin A-binding sites on normal as compared with transformed or protease-treated normal cells lies not in the inherent topography of binding sites, but rather in the susceptibility of the sites to aggregation by concanavalin A. The latter may reflect an increased mobility of lectin-binding sites on transformed or protease-treated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352644"}
{"pmid": "4352645", "title": "Response of Dictyostelium plasma membranes to adenosine 3':5'-cyclic monophosphate.", "content": "Response of Dictyostelium plasma membranes to adenosine 3':5'-cyclic monophosphate. Myxamoebae of the cellular slime mold Dicytostelium discoideum aggregate in response to a chemotactic substance identified as adenosine 3':5'-cyclic monophosphate. Upon aggregation cell division is suppressed, the cells become adhesive, and differentiation is initiated. Freeze-fracture studies of myxamoebae were conducted to determine the effect of cyclic AMP and calcium on plasma membrane ultrastructure. The inner surfaces of the plasma membranes exhibited particulate structures whose sizes (43-187 A) and frequency distribution were determined. Cyclic AMP and calcium induced within 2 hr the formation of particles having average diameters 1.7-times and 1.5-times greater, respectively, than those of the vegetative myxamoebae controls. These data suggest that cyclic AMP mobilizes the intracellular calcium which may be effective in changing plasma membrane structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352645"}
{"pmid": "4352646", "title": "\"Early\" virus-specific RNA may contain information necessary for chromosome replication and mitosis induced by Simian Virus 40.", "content": "\"Early\" virus-specific RNA may contain information necessary for chromosome replication and mitosis induced by Simian Virus 40. Simian Virus 40 (SV40) induces in \"contact-inhibited\" tissue culture cells of mouse kidney an abortive infection that leads to the appearance of intra-nuclear SV40-specific tumor (T-) antigen, followed by replication of the mouse-cell chromatin and mitosis, while no viral progeny DNA or capsid protein is produced. Synthesis of \"early\" SV40-specific RNA (\"19S RNA\") begins a few hours before the appearance of T-antigen and appears to be switched off after the onset of chromatin replication. As the most simple working hypothesis that can account for the experimental results available, we assume that early SV40 RNA contains information necessary for production of T-antigen and that this antigen (or an unknown early virus-specific function that would simply parallel the appearance of T-antigen) activates or de-inhibits a cellular regulatory element that governs chromosome replication and mitosis. The experimental results agree with the idea that SV40 acts primarily as a mitogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352646"}
{"pmid": "4352647", "title": "Pleiotypic control by cyclic AMP: interaction with cyclic GMP and possible role of microtubules.", "content": "Pleiotypic control by cyclic AMP: interaction with cyclic GMP and possible role of microtubules. Previous studies have shown that exogenous dibutyryl cyclic AMP inhibits the uptake of uridine, leucine, and 2-deoxyglucose by cultured mouse fibroblasts. 3':5'-cyclic GMP is shown here to counteract these inhibitory effects as well as the inhibition of precursor transport and leucine incorporation into proteins produced by prostaglandin E(1). We conclude, therefore, that cyclic GMP antagonizes the \"pleiotypic\" effects of cyclic AMP in these cells. Colcemid and vinblastine, but not cytochalasin B, reverse the transport inhibition caused by cyclic AMP without affecting the intracellular concentrations of cyclic AMP. These results suggest the possibility that cyclic AMP regulates the membrane transport of certain substrates by influencing the organization of microtubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352647"}
{"pmid": "4352648", "title": "Cell contact-dependent increase in membrane D-galactopyranosyl-like residues on normal, but not virus- or spontaneously-transformed, murine fibroblasts.", "content": "Cell contact-dependent increase in membrane D-galactopyranosyl-like residues on normal, but not virus- or spontaneously-transformed, murine fibroblasts. Ricinus communis agglutinin (a lectin specific for beta-D-galactopyranosyl-like oligosaccharide residues) was used to investigate differences in lectin-binding sites on normal 3T3 and transformed SV3T3 and 3T12 cells grown to various cell densities in culture. The agglutinability of SV3T3 cells by R. communis agglutinin decreased when cells were grown to confluency or to a point where the cells were in contact. The agglutinability of 3T3 cells also decreased at confluency, but this result was variable and not as dramatic as with SV3T3 cells. Saturation-binding experiments performed at 4 degrees with (125)I-labeled R. communis agglutinin were used to monitor the number of lectin-binding sites on cells grown to different densities. Transformed cells (SV3T3 and 3T12) did not show cell-culture density-dependent changes in R. communis sites; sparse, touching, and confluent transformed cells had equivalent numbers of sites. However, touching (or confluent) 3T3 cells possessed 2.5-times the number of R. communis sites per cell compared to growing, sparsely populated 3T3 cells. When growing sparse 3T3 cells are compared to growing SV3T3 or 3T12 cells, there are 5-times R. communis sites per unit surface area on the transformed cells. The change in R. communis sites during cell growth in culture is discussed in relation to membrane fluidity and topography of plasma membrane oligosaccharides and glycosyl transferases, which can modify cell surfaces at contact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352648"}
{"pmid": "4352650", "title": "Reduction of ferricytochrome c by dithionite ion: electron transfer by parallel adjacent and remote pathways.", "content": "Reduction of ferricytochrome c by dithionite ion: electron transfer by parallel adjacent and remote pathways. The kinetics of the reduction of horseheart ferricytochrome c by sodium dithionite (phosphate buffer-sodium chloride; pH 6.5, mu = 1.0, 25 degrees ) features two reaction pathways; one with the rate constant k(3) = 1.17 x 10(4) M(-1) sec(-1), the other with the rate constant k(1)k(2)/k(-1) = 6.0 x 10(4) M(-1) sec(-1). These pathways are interpreted in terms of remote attack (possibly by way of the exposed edge of the porphyrin system) and adjacent attack (requiring the opening of the heme crevice). The limiting rate for the adjacent pathway (k(1) = 30 sec(-1)) is in good agreement with the rate of heme-crevice opening of ferricytochrome c determined in other studies. The implication of the adjacent attack pathway to the function of cytochrome c in vivo is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352650"}
{"pmid": "4352649", "title": "A general method of gene isolation.", "content": "A general method of gene isolation. A general method of gene isolation has been developed that involves the chemical linkage of RNA to cellulose by a water-soluble carbodiimide, and the continuous circulation of DNA containing specific sequences complementary to the RNA. The temperature of the cellulose matrix is maintained at 37 degrees (50% formamide, 0.3 M NaCl-0.03 M Na(3) citrate) to allow efficient DNA-RNA interaction in the stationary phase, while unreacted and any reassociated DNA is denatured at 90 degrees and then recirculated into the hybridization chamber. Between 40 and 45% of fragmented (32)P-labeled simian virus (SV)40 DNA was removed from the circulating solution when cellulosebound SV40-specific RNA, assymmetrically transcribed in vitro with Escherichia coli RNA polymerase, was used. In the presence of 10(4)-fold excess of sheared E. coli DNA, nearly half of the [(32)P]SV40 DNA was recovered from the mixture as a DNA-RNA hybrid with negligible contamination by bacterial DNA. The isolation procedure is almost quantitative for the complementary DNA. The efficiency and selectivity of this method permit the isolation of a defined DNA sequence from a large and complex genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352649"}
{"pmid": "4352651", "title": "A new enzymatic assay for guanosine 3':5'-cyclic monophosphate and its application to the ductus deferens of the rat.", "content": "A new enzymatic assay for guanosine 3':5'-cyclic monophosphate and its application to the ductus deferens of the rat. A sensitive enzymatic procedure has been developed for the determination of guanosine 3':5'-cyclic monophosphate (cyclic GMP). It is based on the conversion of cyclic GMP to GMP by cyclic nucleotide phosphodiesterase and on the transfer of (32)P from [gamma-(32)P]ATP to GMP by the action of a specific ATP:GMP phosphotransferase (EC 2.7.4.8). The [(32)P]GDP is separated from the remaining [(32)P]ATP by enzymatic degradation of ATP by myosin and by precipitation of the (32)P(i) formed. The reaction blank, which is mostly caused by the nucleotide content of the enzymes, is doubled by about 0.1 pmol of cyclic GMP. The procedure has advantages in speed and/or accuracy over other methods in current use. Cyclic nucleotide concentrations were studied in the ductus deferens of the rat; two agents were used, carbachol and norepinephrine, which cause contraction. Incubation with 0.1 mM carbachol caused a 3-fold increase in cyclic GMP content, which was maximal about 2 min after carbachol addition. Cyclic AMP concentrations were not significantly changed. Addition of 0.01 mM norepinephrine increased cyclic GMP content by about 25% within 1 min and by 40% within 3 min; cyclic AMP concentrations were only slightly increased. A 3-min incubation with the phosphodiesterase inhibitor 1-methyl-3-isobutylxanthine (0.1 mM) doubled the cyclic GMP content and increased cyclic AMP concentration by 50%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352651"}
{"pmid": "4352653", "title": "Identification of a large polypeptide precursor of avian oncornavirus proteins.", "content": "Identification of a large polypeptide precursor of avian oncornavirus proteins. Antibody to partially disrupted avian myeloblastosis virus was used to selectively precipitate newly synthesized intracellular viral polypeptides from extracts of infected chicken cells. When analyzed by sodium dodecyl sulfate-gel electrophoresis, immune precipitates from extracts of cells pulse-labeled for 10 min with [(35)S]methionine contain none of the major virion polypeptides. Instead they show prominent viral specific polypeptides of molecular weight 76,000 and 12,000, as well as minor quantities of other labeled polypeptides. From pulse-chase kinetics and two-dimensional tryptic finger-prints it appears that the large polypeptide is a precursor of at least the two major virion proteins of molecular weights 24,000 and 11,000, while the smaller is a precursor of the 11,000-dalton virion protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352653"}
{"pmid": "4352652", "title": "Cytochalasin blocks sympathetic ganglionic transmission: a presynaptic effect antagonized by pyruvate.", "content": "Cytochalasin blocks sympathetic ganglionic transmission: a presynaptic effect antagonized by pyruvate. The mold metabolite cytochalasin B blocked transmission through the perfused superior cervical sympathetic ganglion of the cat. Acetylcholine injected close-arterially during block continued to excite the ganglion cells so that failure was presynaptic and, by inference, due to reduced output of acetylcholine from the preganglionic nerves. This blocking effect of cytochalasin was reduced by pyruvate. It is concluded that cytochalasin inhibits cholinergic nervous function and it does so, at least in part, by depressing energy production at some stage before pyruvate formation. One possibility is a block of glucose uptake for which there is evidence from other cell types. A more general conclusion is that inhibitory effects of cytochalasin on other secretory systems may also involve such a metabolic component and do not necessarily reflect an interaction of the drug with microfilaments as has been commonly supposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352652"}
{"pmid": "4352654", "title": "Membrane changes and adenosine triphosphate content in normal and malignant transformed cells.", "content": "Membrane changes and adenosine triphosphate content in normal and malignant transformed cells. Transformed fibroblasts had a low content of ATP when grown at a high cell density and a high content of ATP when grown at a low cell density. Concanavalin A agglutinated transformed cells with a low, but not those with a high, ATP content. Transformed cells with a high ATP content gained agglutinability after ATP depletion by inhibitors of the energy-generating systems, and those with a low ATP content lost their agglutinability after restoration of a high ATP content by glucose. Fixation of the surface membrane by formaldehyde, glutaraldehyde, or LaCl(3), inhibited agglutination of cells with an ATP content that allows agglutination. Normal fibroblasts grown at a high or a low cell density were not agglutinated by concanavalin A. Depletion of the cellular ATP content of normal cells induced agglutination only in cells grown at a high, but not at a low, cell density. A similar number of concanavalin A molecules was bound to the surface membrane of agglutinating and nonagglutinating fibroblasts. It is suggested that a high content of ATP inhibits the movement of concanavalin A binding sites, and that a low content of ATP allows, in transformed cells, a new distribution of binding sites to form the clusters required for cell agglutination. Agglutinability of transformed cells is determined by ATP content, and in normal cells changes in the content of ATP are by themselves not sufficient to induce agglutination. Transformed cells, therefore, do not have a control, presumably for membrane stability, that exists in normal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352654"}
{"pmid": "4352655", "title": "A temperature-sensitive change in the energy of activation of hormone-stimulated hepatic adenylyl cyclase.", "content": "A temperature-sensitive change in the energy of activation of hormone-stimulated hepatic adenylyl cyclase. We describe an abrupt increase (at 32 degrees ) in the energy of activation for the reaction of hepatic adenylyl cyclase in the presence of glucagon or epinephrine. This increase is not seen in the presence of fluoride, prostaglandin E(1), or 1-propanol, or in the absence of cyclase stimulators. The change in energy of activation found with hormones is abolished by 1-propanol. This change does not represent differences in hormone or substrate binding at different temperatures, but seems to reflect interactions among elements of the cyclase stimulation sequence. Similar changes in energy of activation were not observed for alkaline phosphatase, cyclic AMP-phosphodiesterase, 5'-nucleotidase, or ouabain-sensitive ATPase. Since the mole fraction of cholesterol in liver membranes is sufficiently high to preclude a phase change in bulk membrane lipids, our observation suggests either that cyclase is restricted to cholesterol-poor membrane regions or that the change in its energy of activation is largely restricted to protein components of the cyclase apparatus. The data are compatible with fundamental differences in the stimulation process(es) for the hormones (glucagon and epinephrine) as compared with those for fluoride and prostaglandin E(1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352655"}
{"pmid": "4352657", "title": "Activation by adenosine 3':5'-monophosphate of a membrane-bound phosphoprotein phosphatase from toad bladder.", "content": "Activation by adenosine 3':5'-monophosphate of a membrane-bound phosphoprotein phosphatase from toad bladder. Adenosine 3':5'-monophosphate (cyclic AMP) caused a decrease in the net rate of incorporation of radioactive phosphate into a specific protein (protein D) in a membrane fraction from toad bladder. Moreover, when the membrane protein was prelabeled with radioactive phosphate, cyclic AMP caused an increase in the net rate of removal of radioactive phosphate from this specific protein. Certain agents were shown to be selective inhibitors of membrane-bound protein D kinase or protein D phosphatase. With the help of these agents, it was concluded that cyclic AMP caused the activation of membrane-bound protein D phosphatase. The present data, together with earlier studies, are compatible with the possibility that the cyclic AMP-induced activation of a membrane-bound phosphoprotein phosphatase in toad bladder, with the consequent dephosphorylation of protein D, may be responsible for the physiological effects of antidiuretic hormone on sodium and/or water transport in this tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352657"}
{"pmid": "4352658", "title": "Spin-state correlations in near infrared spectroscopy of cytochrome c'.", "content": "Spin-state correlations in near infrared spectroscopy of cytochrome c'. Characteristic absorption spectra in the ultraviolet, visible, and near infrared regions are correlated with spin state in ferriheme proteins. Weak, diffuse bands in the near infrared exhibit maxima at about 1000-1100 nm (high spin) and at about 1450-1750 nm (low spin). In these and earlier studies such correlations have been established for several ferriheme proteins, but less extensively than in the more well-known cases of Soret and visible band maxima. We have strengthened the correlation in the near infrared by measurements of absorption spectra in Rhodospirillum rubrum cytochrome c', a variant c-type cytochrome that exhibits a pH-induced transition from high-spin to low-spin state as the pH varies from 6.3 to 13.1. Data are provided on extinction coefficients of characteristic absorption bands at various pH values, obtained by comparison with those measured under the same conditions for horse-heart ferricytochrome c. It is concluded that good correlations of spin state with absorption behavior exist over the entire spectroscopic range from 250 to 2500 nm and that the basic assignments of absorption bands to in-plane charge transfer processes are consistent with these correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352658"}
{"pmid": "4352656", "title": "Induction of lymphocyte transformation by sequential treatment with neuraminidase and galactose oxidase.", "content": "Induction of lymphocyte transformation by sequential treatment with neuraminidase and galactose oxidase. Treatment of mouse-spleen cells with galactose oxidase (EC 1.1.3.9) after incubation with neuraminidase (EC 3.2.1.18) induced extensive blastogenesis. Treatment of the cells with galactose oxidase before incubation with neuraminidase had very little stimulatory effect. Either of these enzymes alone had practically no effect on the cells. The lymphocyte transformation induced by galactose oxidase in neuraminidase-treated cells was decreased upon reacting the cells with borohydride or hydroxylamine, whereas treatment with these compounds did not affect transformation of cells by concanavalin A. It is suggested that galactosyl residues exposed by the action of neuraminidase on the cell membrane are oxidized by galactose oxidase, and the aldehyde moiety thus formed is involved in the induction of blastogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352656"}
{"pmid": "4352659", "title": "Protein kinase activity in erythrocyte ghosts of patients with myotonic muscular dystrophy.", "content": "Protein kinase activity in erythrocyte ghosts of patients with myotonic muscular dystrophy. Myotonic muscular dystrophy is a disorder of humans that involves many organ systems. Physiological studies have suggested that the fundamental defect is of membrane origin. Heretofore, no reproducible metabolic abnormalities have been demonstrated. In the present studies we used erythrocyte ghosts as a convenient source of purified membranes that do not possess changes of denervation, dystrophy, and fibrosis that might complicate the interpretation of muscle membrane changes. Our experiments demonstrated a significant difference in the phosphorylation of erythrocyte ghost protein by [gamma-(32)P]ATP, with endogenous protein kinase of erythrocyte membrane as the enzyme source. After ghosts were kept for 1 week at -20 degrees , phosphorylation of membrane protein in eight controls was twice as high as endogenous protein kinase activity measured in fresh preparations. No stimulation was seen in preparations from seven myotonic dystrophy patients from three different families. This reproducible difference in normal and myotonic membranes may represent an important new approach to studies of this debilitating inborn error of metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352659"}
{"pmid": "4352661", "title": "Glia-induced morphological differentiation in neuroblastoma cells.", "content": "Glia-induced morphological differentiation in neuroblastoma cells. Glial cells release a factor into their culture medium that induces a high degree of morphological differentiation in neuroblastoma cells under normal growth conditions. This phenomenon is not correlated with a change in intracellular adenosine 3':5'-cyclic monophosphate or in the rate of cell growth. Media from other cell lines tested induce less morphological differentiation or have no effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352661"}
{"pmid": "4352660", "title": "Common cell-surface antigen associated with murine and feline C-type RNA leukemia viruses.", "content": "Common cell-surface antigen associated with murine and feline C-type RNA leukemia viruses. A new common cell-surface antigen associated with murine and feline C-type RNA leukemia viruses was demonstrated by the use of rabbit antiserum against feline leukemia virus and the indirect membrane immunofluorescence test. Common cell-surface antigen was found in all leukemias of all strains of mice tested, in normal lymphoid tissues of Gross-positive (high incidence of leukemia) mouse strains AKR, AKR.H-2(b), C58, and NZB, in cultured rat fibroblasts infected with Rauscher virus, in cultured feline fibroblasts infected with feline leukemia virus, and in spontaneous feline lymphosarcoma. The antigen was not demonstrable in normal adult and fetal tissues of Gross-negative mouse strains or in tissues and cultured fibroblasts derived from normal rats and normal cats. The immunoferritin study of murine leukemia cells revealed that the antigen was located on the cell surface in discrete areas; budding and C-type RNA viral envelope was not labeled as antigen site. The distribution of common cell-surface antigen on murine and feline leukemias, as well as on normal lymphoid tissues of Gross-positive mouse strains, indicates the presence of an antigen distinct from any cell-surface antigen heretofore shown to be associated with, or specified by, mammalian C-type RNA viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352660"}
{"pmid": "4352663", "title": "Detection and assessment of case clustering in Burkitt's lymphoma and Hodgkin's disease.", "content": "Detection and assessment of case clustering in Burkitt's lymphoma and Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352663"}
{"pmid": "4352662", "title": "Primary carcinomas of the liver in Hong Kong: some possible aetiological factors.", "content": "Primary carcinomas of the liver in Hong Kong: some possible aetiological factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352662"}
{"pmid": "4352664", "title": "Epidemiologic and immunologic considerations on the pathogenesis of Burkitt's Tumor.", "content": "Epidemiologic and immunologic considerations on the pathogenesis of Burkitt's Tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352664"}
{"pmid": "4352665", "title": "Etiology of Burkitt's lymphoma.", "content": "Etiology of Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352665"}
{"pmid": "4352666", "title": "Multiplicity of lung tumour classifications.", "content": "Multiplicity of lung tumour classifications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352666"}
{"pmid": "4352668", "title": "Histoenzymologic and biochemical investigations into the nervous tissue round an experimentally-induced cerebral hemorrhagic focus.", "content": "Histoenzymologic and biochemical investigations into the nervous tissue round an experimentally-induced cerebral hemorrhagic focus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352668"}
{"pmid": "4352667", "title": "Investigation on the epidemiological significance of detailed cancer data--preliminary results.", "content": "Investigation on the epidemiological significance of detailed cancer data--preliminary results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352667"}
{"pmid": "4352670", "title": "Plasma lipoproteins and hyperlipoproteinemia.", "content": "Plasma lipoproteins and hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352670"}
{"pmid": "4352672", "title": "Ophthalmoscopic findings and changes in hormonal and metabolic parameters in \"protodiabetes\".", "content": "Ophthalmoscopic findings and changes in hormonal and metabolic parameters in \"protodiabetes\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352672"}
{"pmid": "4352671", "title": "Comparative metabolic and clinical studies of sexual ateliotic dwarfs and diabetics.", "content": "Comparative metabolic and clinical studies of sexual ateliotic dwarfs and diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352671"}
{"pmid": "4352673", "title": "Kidney structural abnormalities in early diabetes.", "content": "Kidney structural abnormalities in early diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352673"}
{"pmid": "4352674", "title": "Ultrastructural pathology of periperal nervous system in early diabetes.", "content": "Ultrastructural pathology of periperal nervous system in early diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352674"}
{"pmid": "4352675", "title": "Neurological findings in chemical diabetes.", "content": "Neurological findings in chemical diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352675"}
{"pmid": "4352676", "title": "Neurological changes in early diabetes.", "content": "Neurological changes in early diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352676"}
{"pmid": "4352677", "title": "Clinical features of peripheral neuropathy associated with hypoglycemia.", "content": "Clinical features of peripheral neuropathy associated with hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352677"}
{"pmid": "4352678", "title": "Malakoplakia of the skin: report of a case.", "content": "Malakoplakia of the skin: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352678"}
{"pmid": "4352679", "title": "Lymphography and patients' reactions.", "content": "Lymphography and patients' reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352679"}
{"pmid": "4352680", "title": "Initial psychological research related to the Occupational Safety and Health Act of 1970.", "content": "Initial psychological research related to the Occupational Safety and Health Act of 1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352680"}
{"pmid": "4352681", "title": "Anesthetic effects on cerebral metabolism.", "content": "Anesthetic effects on cerebral metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352681"}
{"pmid": "4352686", "title": "Electroretinogram and afferent visual transmission in the epileptic baboon Papio papio. Effects of drugs influencing monoaminergic systems.", "content": "Electroretinogram and afferent visual transmission in the epileptic baboon Papio papio. Effects of drugs influencing monoaminergic systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352686"}
{"pmid": "4352685", "title": "Treatment of infantile spasms and Lennox-Gastaut syndrome with clonazepam (Rivotril).", "content": "Treatment of infantile spasms and Lennox-Gastaut syndrome with clonazepam (Rivotril).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352685"}
{"pmid": "4352687", "title": "Preparation and purification of a structural sialofucoglycoprotein from the bovine lens capsule.", "content": "Preparation and purification of a structural sialofucoglycoprotein from the bovine lens capsule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352687"}
{"pmid": "4352688", "title": "Lens polyol dehydrogenase.", "content": "Lens polyol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352688"}
{"pmid": "4352689", "title": "Morphology and biological properties of transplantable tumours induced by polyoma virus.", "content": "Morphology and biological properties of transplantable tumours induced by polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352689"}
{"pmid": "4352690", "title": "Relationships among pollution indicator bacteria isolated from raw water and distribution systems by the presence-absence (P-A) test.", "content": "Relationships among pollution indicator bacteria isolated from raw water and distribution systems by the presence-absence (P-A) test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352690"}
{"pmid": "4352691", "title": "Effect of anaerobiosis on respiratory rate, cytochrome oxidase activity and mitochondrial structures in coleoptiles of rice (Oryza sativa L.).", "content": "Effect of anaerobiosis on respiratory rate, cytochrome oxidase activity and mitochondrial structures in coleoptiles of rice (Oryza sativa L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352691"}
{"pmid": "4352692", "title": "Studies on contract inhibition of growth in the mouse fibroblast, 3T3. I. Changes in cell size and composition during 'unrestricted' growth.", "content": "Studies on contract inhibition of growth in the mouse fibroblast, 3T3. I. Changes in cell size and composition during 'unrestricted' growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352692"}
{"pmid": "4352693", "title": "Studies on contact inhibition of growth in the mouse fibroblast, 3T3. II. Effects of amino acid deprivation and serum on growth rate.", "content": "Studies on contact inhibition of growth in the mouse fibroblast, 3T3. II. Effects of amino acid deprivation and serum on growth rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352693"}
{"pmid": "4352695", "title": "The future of medical practice.", "content": "The future of medical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352695"}
{"pmid": "4352694", "title": "Relapsing peripheral neuropathy in association with renal carcinoma.", "content": "Relapsing peripheral neuropathy in association with renal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352694"}
{"pmid": "4352700", "title": "Genetic origin of RD114 and other RNA tumour viruses assayed by molecular hybridization.", "content": "Genetic origin of RD114 and other RNA tumour viruses assayed by molecular hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352700"}
{"pmid": "4352699", "title": "Purification of oestradiol receptors by affinity chromatography.", "content": "Purification of oestradiol receptors by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352699"}
{"pmid": "4352701", "title": "Extensive homology of RD114 virus DNA with RNA of feline cell origin.", "content": "Extensive homology of RD114 virus DNA with RNA of feline cell origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352701"}
{"pmid": "4352702", "title": "Partial characterization of RD114 virus by DNA-RNA hybridization studies.", "content": "Partial characterization of RD114 virus by DNA-RNA hybridization studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352702"}
{"pmid": "4352703", "title": "Measurement of RD114 virus nucleotide sequences in feline cellular DNA.", "content": "Measurement of RD114 virus nucleotide sequences in feline cellular DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352703"}
{"pmid": "4352707", "title": "A practitioner's experiences with adenoviral infection in Arabian foals.", "content": "A practitioner's experiences with adenoviral infection in Arabian foals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352707"}
{"pmid": "4352709", "title": "Intensification of hypertriglyceridemia by either alcohol or carbohydrate.", "content": "Intensification of hypertriglyceridemia by either alcohol or carbohydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352709"}
{"pmid": "4352711", "title": "Cyclic AMP in digestive physiology.", "content": "Cyclic AMP in digestive physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352711"}
{"pmid": "4352710", "title": "Absorption of fortification iron in bread.", "content": "Absorption of fortification iron in bread.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352710"}
{"pmid": "4352712", "title": "Evaluation of live-virus vaccine against avian encephalomyelitis in turkey breeder hens.", "content": "Evaluation of live-virus vaccine against avian encephalomyelitis in turkey breeder hens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352712"}
{"pmid": "4352713", "title": "Ultrastructural comparison of morphogenesis and fate of Marek's disease and infectious laryngotracheitis viruses in chicken kidney cells.", "content": "Ultrastructural comparison of morphogenesis and fate of Marek's disease and infectious laryngotracheitis viruses in chicken kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352713"}
{"pmid": "4352714", "title": "A polymer of N-acetylglucosamine 1-phosphate in the wall of Staphylococcus lactis 2102.", "content": "A polymer of N-acetylglucosamine 1-phosphate in the wall of Staphylococcus lactis 2102. 1. Walls of Staphylococcus lactis 2102 contain about 40% of a phosphorylated polysaccharide, which was isolated by extraction with cold trichloroacetic acid, with dilute NaOH, and also by digestion with a Flavobacterium peptidase. 2. The purified polymer contained equimolar proportions of N-acetylglucosamine and phosphate as its sole constituents and was readily hydrolysed under gentle acidic conditions to N-acetylglucosamine 6-phosphate. 3. Studies on the intact polymer showed that it is linear and that adjacent acetamido sugar units are joined by phosphodiester bonds between their 1- and 6-positions, the glycosidic linkages having the alpha-configuration. This polymer is thus the simplest of the known microbial wall polymers possessing sugar 1-phosphate linkages. 4. Alkali degradation of the extracted polymer proceeds predominantly in a stepwise manner from the reducing end, but evidence was obtained for the direct hydrolysis of some of the inter-unit phosphodiester groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352714"}
{"pmid": "4352715", "title": "Isolation and characterization of C1q, a subcomponent of the first component of complement, from human and rabbit sera.", "content": "Isolation and characterization of C1q, a subcomponent of the first component of complement, from human and rabbit sera. 1. C1q, a subcomponent of the first component of complement, has been isolated, in a haemolytically active and soluble form, by ion-exchange chromatography and gel filtration, from human and rabbit sera. Yields ranged from 10 to 25mg/litre of serum and the activity of final preparations was consistently in the range 5x10(3)-15x10(3) C1qH(50) units/mg. 2. The molecular weights of human and rabbit subcomponent C1q were 409600 and 417600, as determined by sedimentation equilibrium studies. 3. Subcomponent C1q from both species was shown to be composed of non-covalently linked subunits of approximately 57000 molecular weight as determined by gel-filtration or sedimentation equilibrium studies in 5.3m-guanidinium chloride. Reduction or oxidation of human and rabbit subcomponent C1q yielded three chains each having a molecular weight of approximately 23000 and which differed slightly in amino acid composition but markedly in carbohydrate content. The oxidized chains were separated, on a preparative scale, by ion-exchange chromatography in 8m-urea on DEAE-cellulose. 4. Both human and rabbit subcomponent C1q contained hydroxyproline, hydroxylysine, a high percentage of glycine and approximately 8% carbohydrate. Glutamic acid and aspartic acid were the free N-terminal amino acids of human subcomponent C1q whereas only serine was found in rabbit subcomponent C1q. 5. Collagenase digestion of human or rabbit subcomponent C1q caused a rapid loss of haemolytic activity which correlated with the breakdown of collagenous regions in the molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352715"}
{"pmid": "4352716", "title": "Anthranilate synthase-anthranilate 5-phosphoribosyl 1-pyrophosphate phosphoribosyltransferase from Aerobacter aerogenes.", "content": "Anthranilate synthase-anthranilate 5-phosphoribosyl 1-pyrophosphate phosphoribosyltransferase from Aerobacter aerogenes. 1. Anthranilate synthase and phosphoribosyltransferase from Aerobacter aerogenes purify simultaneously and sediment together on sucrose gradients, showing that they occur as an enzyme aggregate. Both activities of the intact aggregate are subject to inhibition by tryptophan. 2. By using appropriate auxotrophic mutants it was shown that an intact active enzyme aggregate is formed when the components come from separate mutant strains. An intact active aggregate can also be formed when one component is from Escherichia coli and the other from A. aerogenes. 3. Phosphoribosyltransferase of A. aerogenes is active when not in an aggregate with anthranilate synthase, but is not subject to tryptophan inhibition, indicating that the inhibitor site is on the anthranilate synthase component. 4. Anthranilate synthase can be active and sensitive to tryptophan inhibition when complexed with an inactive phosphoribosyltransferase. 5. Kinetic studies on the anthranilate synthase activity show that tryptophan is a competitive inhibitor with respect to chorismate and a non-competitive inhibitor with respect to either glutamine or NH(4) (+) ions. This is consistent with a sequential mechanism of the ordered type in which chorismate is the first reactant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352716"}
{"pmid": "4352718", "title": "The amino acid sequences of cytochromes c-551 from three species of Pseudomonas.", "content": "The amino acid sequences of cytochromes c-551 from three species of Pseudomonas. The amino acid sequences of the cytochromes c-551 from three species of Pseudomonas have been determined. Each resembles the protein from Pseudomonas strain P6009 (now known to be Pseudomonas aeruginosa, not Pseudomonas fluorescens) in containing 82 amino acids in a single peptide chain, with a haem group covalently attached to cysteine residues 12 and 15. In all four sequences 43 residues are identical. Although by bacteriological criteria the organisms are closely related, the differences between pairs of sequences range from 22% to 39%. These values should be compared with the differences in the sequence of mitochondrial cytochrome c between mammals and amphibians (about 18%) or between mammals and insects (about 33%). Detailed evidence for the amino acid sequences of the proteins has been deposited as Supplementary Publication SUP 50015 at the National Lending Library for Science and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1973), 131, 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352718"}
{"pmid": "4352717", "title": "A membrane-bound activity catalysing phosphatidylinositol breakdown to 1,2-diacylglycerol, D-myoinositol 1:2-cyclic phosphate an D-myoinositol 1-phosphate. Properties and subcellular distribution in rat cerebral cortex.", "content": "A membrane-bound activity catalysing phosphatidylinositol breakdown to 1,2-diacylglycerol, D-myoinositol 1:2-cyclic phosphate an D-myoinositol 1-phosphate. Properties and subcellular distribution in rat cerebral cortex. 1. Breakdown of phosphatidylinositol was studied in homogenates and subcellular fractions of rat cerebral cortex by using both membrane-bound and externally added [(32)P]phosphatidylinositol as substrate. 2. In the presence of deoxycholate breakdown followed first-order kinetics at low substrate concentrations ([unk]1mm) and zero-order kinetics at higher concentrations (6-9mm). 3. Maximum breakdown by cerebral-cortex homogenates was approximately 0.5mumol/h per mg of protein and occurred at pH7.0 in the presence of 8mm-phosphatidylinositol, 2mm-CaCl(2) and 2mg of deoxycholate/ml. Activity was abolished by 1mm-ethanedioxybis(ethylamine)tetra-acetate. 4. The products of phosphatidylinositol breakdown were 1,2-diacylglycerol and a mixture of d-myoinositol 1:2-cyclic phosphate (55%) and d-myoinositol 1-phosphate (45%). The two phosphate esters appeared to be produced together and in constant proportions. 5. Some 51% of the activity was particle-bound, with the highest activities in small nerve endings, microsomal material and two synaptic membrane fractions (fractions Mic(20), Mic(100), M(1) 1.0 and M(1) 0.9 respectively), all of which were also rich in acetylcholinesterase and which have been shown to be rich in other surface-membrane enzymes. Much of the particle-bound activity therefore appears to be present in cerebral-cortex plasma membranes. 6. The results are discussed in relation to previously described soluble activities that catalyse the same reaction, and to a possible role of the membrane-bound enzyme in enhanced phosphatidylinositol turnover in externally stimulated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352717"}
{"pmid": "4352719", "title": "The nature of polydisperse ribonucleic acid in plants.", "content": "The nature of polydisperse ribonucleic acid in plants. The aggregation of ribosomal RNA species during chromatography on methylated albumin on kieselguhr was decreased from 50 to 15% by the lower salt concentrations made possible by the use of higher pH values. The polydisperse RNA was resolved into two fractions. About 50% was eluted with the rRNA whereas the remainder was bound to the column, and was recovered only by solubilization of the methylated albumin. Both fractions of polydisperse RNA were similar in size range, but the bound fraction was considerably richer in AMP. No D-RNA (DNA-like RNA) peak was resolved under these conditions of column fractionation. However, the properties of the bound RNA were consistent with it containing both D-RNA and TB-RNA (tenaciously bound RNA). The relationship between these two fractions of AMP-rich RNA was considered. The bound RNA and ribosomal RNA responded differently to various treatments. The salt concentration required to elute ribosomal RNA was halved by increasing the pH of the fractionation, but the amount of bound RNA was in fact increased. Denaturation by hot urea decreased the binding of ribosomal RNA to the methylated albumin, but did not facilitate elution of bound RNA. The high affinity between the AMP-rich polydisperse RNA and the methylated albumin does not therefore appear to arise for the secondary structure conferred by the high AMP content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352719"}
{"pmid": "4352722", "title": "Iron metabolism in the veal calf. 2. Iron requirements and the effect of copper supplementation.", "content": "Iron metabolism in the veal calf. 2. Iron requirements and the effect of copper supplementation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352722"}
{"pmid": "4352720", "title": "Nucleotide sequence analysis with polynucleotide kinase and nucleotide \"mapping\" methods. 5'-Terminal sequences of deoxyribonucleic acid from bacteriophages lambda and 424.", "content": "Nucleotide sequence analysis with polynucleotide kinase and nucleotide \"mapping\" methods. 5'-Terminal sequences of deoxyribonucleic acid from bacteriophages lambda and 424. The polynucleotide kinase reaction was used in analyses of complex mixtures of oligodeoxynucleotides which were fractionated by various two-dimensional nucleotide ;mapping' procedures. Parallel ionophoretic analyses on DEAE-cellulose paper, pH2, and AE-cellulose paper, pH3.5, of venom phosphodiesterase partial digests of 5'-terminally labelled oligonucleotides enabled the sequence of the nucleotides to be deduced uniquely. A ;diagonal ionophoresis' method has been used with mixtures of nucleotides. Application of these methods to 5'-terminally labelled DNA from bacteriophage lambda gave the terminal sequences pA-G-G-T-C-G and pG-G-G-C-G. Identical 5'-terminal sequences were found with DNA from bacteriophage 424.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352720"}
{"pmid": "4352723", "title": "The effects of supplements varying in carotene and calcium content on the physical, biochemical and skeletal status of preschool children.", "content": "The effects of supplements varying in carotene and calcium content on the physical, biochemical and skeletal status of preschool children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352723"}
{"pmid": "4352724", "title": "Site of latent herpes.", "content": "Site of latent herpes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352724"}
{"pmid": "4352721", "title": "A sequence of seventy-three nucleotides from the coliphage R17 genome.", "content": "A sequence of seventy-three nucleotides from the coliphage R17 genome. 1. A sequence of 73 nucleotides of the RNA genome from coliphage R17 was determined. It can be read through in only one translational frame. The fragment is not part of the coatprotein cistron (Min Jou et al., 1972), nor does it come from the untranslated sequences described previously (Steitz, 1969; Nichols, 1970; Cory et al., 1970; de Wachter et al., 1971; Contreras et al., 1971; Cory et al., 1972). It contains two sequences of 23 and 24 nucleotides, 22 of which are identical. This kind of reiteration is the first one found in bacteriophage nucleic acid. 2. Improved conditions were found and tested for blocking oligonucleotides with carbodi-imide and cleaving by ribonuclease A at cytidylate residues. 3. A synthetic medium is described which allows labelling in vivo with (32)P to give specific radioactivities higher than those obtained in the procedures used previously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352721"}
{"pmid": "4352725", "title": "Infantile herpes zoster after intrauterine exposure to varicella.", "content": "Infantile herpes zoster after intrauterine exposure to varicella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352725"}
{"pmid": "4352726", "title": "Beclomethasone dipropionate steriod aerosol in treatment of perennial allergic asthma in children.", "content": "Beclomethasone dipropionate steriod aerosol in treatment of perennial allergic asthma in children. Thirty-one chronic perennial asthmatics aged from 2(1/2) to 16 years were treated with beclomethasone dipropionate pressurized aerosols for up to 20 months. Of these, 16 patients dependent on oral corticosteroid or corticotrophin for up to 11 years were successfully transferred to this treatment, with one exception. Steroid withdrawal symptoms were slight. Loss of weight, disappearance of Cushingoid features, and resumption of growth indicated lack of systemic side effects. Fifteen others inadequately controlled on bronchodilators or disodium cromoglycate, were also effectively treated, and no clinical evidence of adrenal suppression was noted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352726"}
{"pmid": "4352727", "title": "Inhibitory interaction between X and Y units in the cat lateral geniculate nucleus.", "content": "Inhibitory interaction between X and Y units in the cat lateral geniculate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352727"}
{"pmid": "4352728", "title": "A cholinergic inhibitory system in the frog optic tectum: its role in visual electrical responses and feeding behavior.", "content": "A cholinergic inhibitory system in the frog optic tectum: its role in visual electrical responses and feeding behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352728"}
{"pmid": "4352730", "title": "Synaptogenesis and the development of neurotransmitter enzymes in organotypic cultures of chick spinal cord.", "content": "Synaptogenesis and the development of neurotransmitter enzymes in organotypic cultures of chick spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352730"}
{"pmid": "4352731", "title": "Characterization of central angiotensin II receptors involved in the elicitation of drinking in the rat.", "content": "Characterization of central angiotensin II receptors involved in the elicitation of drinking in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352731"}
{"pmid": "4352732", "title": "Tetanus toxin blocks the efferent endings in the cochlea.", "content": "Tetanus toxin blocks the efferent endings in the cochlea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352732"}
{"pmid": "4352733", "title": "d-Tubocurarine does not antagonize the inhibitory effects of GABA at the crustacean neuromuscular junction.", "content": "d-Tubocurarine does not antagonize the inhibitory effects of GABA at the crustacean neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352733"}
{"pmid": "4352734", "title": "Antagonism of neuronal excitation by 1-hydroxy-3-aminopyrrolidone-2.", "content": "Antagonism of neuronal excitation by 1-hydroxy-3-aminopyrrolidone-2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352734"}
{"pmid": "4352735", "title": "Comparison of effects of noradrenaline and histamine with cyclic AMP on brain stem neurones.", "content": "Comparison of effects of noradrenaline and histamine with cyclic AMP on brain stem neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352735"}
{"pmid": "4352736", "title": "Effects of intracerebral injections of 5,6-dihydroxytryptamine on central monoamine neurons: evidence for selective degeneration of central 5-hydroxytryptamine neurons.", "content": "Effects of intracerebral injections of 5,6-dihydroxytryptamine on central monoamine neurons: evidence for selective degeneration of central 5-hydroxytryptamine neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352736"}
{"pmid": "4352737", "title": "Effect of two ACTH-analogs on noradrenaline metabolism in rat brain.", "content": "Effect of two ACTH-analogs on noradrenaline metabolism in rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352737"}
{"pmid": "4352738", "title": "Cytosol-modulated transport of messenger RNA from isolated nuclei.", "content": "Cytosol-modulated transport of messenger RNA from isolated nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352738"}
{"pmid": "4352740", "title": "Anemia virus as a distinct component of the murine leukemia-sarcoma complex of viruses.", "content": "Anemia virus as a distinct component of the murine leukemia-sarcoma complex of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352740"}
{"pmid": "4352739", "title": "A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.", "content": "A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352739"}
{"pmid": "4352741", "title": "Cholesterol metabolism in rats bearing Morris hepatoma 7777.", "content": "Cholesterol metabolism in rats bearing Morris hepatoma 7777.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352741"}
{"pmid": "4352742", "title": "Modification of hexosaminidase isozymes in rat hepatoma.", "content": "Modification of hexosaminidase isozymes in rat hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352742"}
{"pmid": "4352743", "title": "Glucagon and prostaglandin E1 stimulation of cyclic adenosine 3', 5'-monophosphate levels and adenylate cyclase activity in benign hyperplastic nodules and malignant hepatomas of ethionine-treated rats.", "content": "Glucagon and prostaglandin E1 stimulation of cyclic adenosine 3', 5'-monophosphate levels and adenylate cyclase activity in benign hyperplastic nodules and malignant hepatomas of ethionine-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352743"}
{"pmid": "4352744", "title": "Development of an analytical system based around a miniature fast analyzer.", "content": "Development of an analytical system based around a miniature fast analyzer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352744"}
{"pmid": "4352745", "title": "Viral investigations in ulcerative colitis and regional enteritis.", "content": "Viral investigations in ulcerative colitis and regional enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352745"}
{"pmid": "4352746", "title": "Herpesvirus saimiri: experimental infection of squirrel monkeys (Saimir sciureus).", "content": "Herpesvirus saimiri: experimental infection of squirrel monkeys (Saimir sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352746"}
{"pmid": "4352747", "title": "Tumorigenicity assays in nonhuman primates treated with antithymocyte globulin.", "content": "Tumorigenicity assays in nonhuman primates treated with antithymocyte globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352747"}
{"pmid": "4352750", "title": "Inhibition of human rhabdomyosarcoma-cell growth in agar by dibutyryl cyclic AMP.", "content": "Inhibition of human rhabdomyosarcoma-cell growth in agar by dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352750"}
{"pmid": "4352748", "title": "Effects of the antifertility drug enovid in five strains of mice, with particular regard to carcinogenesis.", "content": "Effects of the antifertility drug enovid in five strains of mice, with particular regard to carcinogenesis. The antifertility drug, Enovid, was tested for possible carcinogenicity in female mice of 5 specially selected strains: BALB/c, C3H, C3HfB, A, and C57BI.  Enovid was chosen for testing since it is one of the most widely used oral contraceptives.  The 5 strains of mice provided maximum genetic variation in the test animals.  The drug was fed at 3 dose levels: 5 mcg/gm, 10 mcg/gm and 20 mcg/gm of food.  The lowest dose did not prevent reproduction.  The 10 mcg dose prevented some females from reproducing.  The 20 mcg dose prevented all females from reproducing.  The strains of mice differed in their response to Enovid.  Weight gain was reduced in all strains.  Effect on life-span varied, partly because of the tumors.  Cervical and vaginal lesions showed invasion of the epithelium into the stroma but was limited, with few exceptions to the BALB/c females.  In the BALB/c strain these lesions occurred in controls as well, but showed more progression and a higher incidence with the highest dose of Enovid.  None of these lesions appeared grossly as tumors and none had extended beyond the vaginal wall or metastasized.  They were observed only on histologic sections.  Neither ovarian nor mammary gland tumors were increased in any strain.  In the C3H strain such tumors seemed to be inhibited.  In the C3HfB strain there was some inhibition of hepatomas and in the BALB/c strain some inhibition of adrenocortical adenoma.  Chromophobe adenomas of the hypophysis were significantly increased in old C57BI females treated with the highest dose of Enovid.  Offspring of Enovid-treated females showed no abnormalities.  Enovid increased the occurrence and may have advanced the progression of epithelial lesions of the cervix and vagina of old BALB/c females.  A study of the lesions in untreated females of this strain might help the understanding of carcinoma in situ in women and possibly the appearance of adeno-carcinoma of the vagina of young women whose mothers had been treated with stilbestrol during the first trimester to maintain pregnancy.   Other neoplasms in this strain were not increased by the Enovid therapy.  In the C3H strain mammary tumors were reduced by the Enovid and those that did occur were found later than in controls.  Results from experimental animals should be applied to humans with care.  Such results are of greatest value in directing attention to certain areas for investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352748"}
{"pmid": "4352749", "title": "C-type virus particles in placentas and fetal tissues of Rhesus monkeys.", "content": "C-type virus particles in placentas and fetal tissues of Rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352749"}
{"pmid": "4352752", "title": "Blastogenic transformation assay for detection of immunologic reactivity to avian oncornaviruses.", "content": "Blastogenic transformation assay for detection of immunologic reactivity to avian oncornaviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352752"}
{"pmid": "4352751", "title": "Rejection of polyoma virus-induced neoplasms in mice inoculated with complement and antiserum.", "content": "Rejection of polyoma virus-induced neoplasms in mice inoculated with complement and antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352751"}
{"pmid": "4352754", "title": "Relationship between nuclear pockets in bovine peripheral blood lymphocytes and C-type virus particles in cultures of these cells.", "content": "Relationship between nuclear pockets in bovine peripheral blood lymphocytes and C-type virus particles in cultures of these cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352754"}
{"pmid": "4352753", "title": "Antibodies associated with Epstein-Barr virus in Burkitt's lymphoma during injections of BCG or irradiated autochthonous tumor cells.", "content": "Antibodies associated with Epstein-Barr virus in Burkitt's lymphoma during injections of BCG or irradiated autochthonous tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352753"}
{"pmid": "4352756", "title": "Amino acid distribution in the nervous system of the crab, Carcinus maenas (L.).", "content": "Amino acid distribution in the nervous system of the crab, Carcinus maenas (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352756"}
{"pmid": "4352755", "title": "Lymphosarcomas in two gibbons (Hylobates lar) with associated C-type virus.", "content": "Lymphosarcomas in two gibbons (Hylobates lar) with associated C-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352755"}
{"pmid": "4352757", "title": "Effects of acetylcholine on the incorporation of (32P)orthophosphate in vitro into the phospholipids of subsynaptosomal, membranes from guinea-pig brain.", "content": "Effects of acetylcholine on the incorporation of (32P)orthophosphate in vitro into the phospholipids of subsynaptosomal, membranes from guinea-pig brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352757"}
{"pmid": "4352758", "title": "Accumulation of adenosine 3', 5'-monophosphate in incubated slices from discrete regions of squirrel monkey cerebral cortex: effect of norepinephrine, serotonin and adenosine.", "content": "Accumulation of adenosine 3', 5'-monophosphate in incubated slices from discrete regions of squirrel monkey cerebral cortex: effect of norepinephrine, serotonin and adenosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352758"}
{"pmid": "4352760", "title": "Metastasising chondroid syringoma.", "content": "Metastasising chondroid syringoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352760"}
{"pmid": "4352759", "title": "Enzymatic regulation of adenosine 3',5'-monophosphate (cyclic AMP) in the freezing epileptogenic lesion of rat brain and in homologous contralateral cortex.", "content": "Enzymatic regulation of adenosine 3',5'-monophosphate (cyclic AMP) in the freezing epileptogenic lesion of rat brain and in homologous contralateral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352759"}
{"pmid": "4352761", "title": "Histologically benign mixed parotid tumour with hepatic metastasis.", "content": "Histologically benign mixed parotid tumour with hepatic metastasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352761"}
{"pmid": "4352762", "title": "Auto-antibodies in acute viral hepatitis, yellow fever, and hepatocellular carcinoma: clinical and experimental findings.", "content": "Auto-antibodies in acute viral hepatitis, yellow fever, and hepatocellular carcinoma: clinical and experimental findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352762"}
{"pmid": "4352763", "title": "Pigmented progonoma in a dermoid cyst of the ovary.", "content": "Pigmented progonoma in a dermoid cyst of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352763"}
{"pmid": "4352764", "title": "The effect of isoprenaline on cyclic AMP concentrations in skeletal muscle.", "content": "The effect of isoprenaline on cyclic AMP concentrations in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352764"}
{"pmid": "4352765", "title": "An inhibition of post-ganglionic motor transmission in the mammalian vas deferens by D-lysergic acid diethylamide.", "content": "An inhibition of post-ganglionic motor transmission in the mammalian vas deferens by D-lysergic acid diethylamide. 1. Under certain conditions D-lysergic acid diethylamide (LSD), 10(-9)-10(-6) g/ml., exerted an immediate, prolonged and slowly reversible inhibitory effect upon the post-ganglionic motor transmission in desheathed guinea-pig vas deferens preparations.2. The most critical factor influencing this action of LSD appeared to be the train length. With short trains of less than 4 or 5 pulses the twitch inhibition produced by LSD was often total. With longer trains (5-20 pulses), the degree of inhibition declined with increase in train length. These results suggest the existence of two components in the motor response to post-ganglionic stimulation, distinguished by their susceptibility to LSD.3. The inhibition of the LSD-susceptible component was related to the dose of LSD in the range 10(-9)-10(-6) g/ml., reaching a maximum at 0.5-1 x 10(-6) g/ml. The response remnants elicited by trains of more than 5 pulses under these conditions could not be reduced further by a ten- to twenty-fold increase in LSD concentration to 10(-5) g/ml. and were in fact slightly potentiated.4. The inhibition of post-ganglionic motor transmission by LSD was not explicable on the basis of an alpha-adrenoceptor blockade because it was not associated with any reduction in motor responses to noradrenaline.5. The use of propranolol excluded mediation of the LSD-inhibition by beta-adrenoceptors.6. The LSD effect was not due to a non-specific smooth muscle depression because it was not associated with any reduction in motor responses to acetylcholine, ATP or bradykinin.7. The inhibitory effect of LSD on post-ganglionic transmission resembled that of noradrenaline in that it was antagonized by phentolamine; another alpha-adrenoceptor blocking agent, phenoxybenzamine, was less effective than phentolamine in this respect.8. The LSD-inhibition was obtained in preparations taken from reserpinized guinea-pigs.9. The inhibition of motor transmission in the vas deferens by LSD was confirmed in rats, Meriones shawii and rabbits.10. The inhibition of post-ganglionic transmission by LSD was unrelated to its ability to antagonize 5-hydroxytryptamine (5-HT), to which the longitudinal muscle of the guinea-pig vas deferens is insensitive. The more potent 5-HT antagonists, methysergide and BOL 148 were either virtually inactive or considerably weaker than LSD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352765"}
{"pmid": "4352766", "title": "Pancreatic acinar cells: ionic dependence of the membrane potential and acetycholine-induced depolarization.", "content": "Pancreatic acinar cells: ionic dependence of the membrane potential and acetycholine-induced depolarization. 1. Intracellular recordings of membrane potentials have been made in vitro from the exocrine acinar cells of the mouse pancreas using glass micro-electrodes.2. The mean membrane potential of the acinar cells during superfusion with Krebs-Henseleit solution was -39.2 mV. Increasing [K](o) tenfold decreased the membrane potential by 28 mV when [K](o) was above 10 mM. This depolarization was not affected by atropine (1.4 x 10(-6)M). Strophanthin-G (10(-3)M) slowly depolarized the cells at about 10 mV hr(-1).3. Brief exposure to acetylcholine (ACh), 5.5 x 10(-5)M, or pancreozymin resulted in a short lasting depolarization of the acinar cells. Atropine (1.4 x 10(-6)M) blocked the depolarizing action of ACh but not that of pancreozymin. Adrenaline (5.5 x 10(-5)M) or cyclic AMP (10(-3)-10(-4)M) did not influence the membrane potential.4. The amplitude of the ACh-induced depolarization was not dependent on the presence of CO(2)/HCO(3) in the bathing fluid, but it was closely dependent on the extracellular Na concentration. However, ACh was still able to evoke a small depolarization even after prolonged exposure of the tissue to a Na-free solution.5. During exposure of the tissue to a Ca-free solution the resting membrane potential was decreased and the ACh-induced depolarization was significantly reduced. Some substances which are known in other tissues to inhibit membrane Ca(2+) currents, i.e. La(3+), D-600 and tetracaine, were able to reduce, but never abolish, the ACh-induced depolarization.6. These results suggest that the effect of ACh on the pancreatic acinar cell is to increase the permeability of the membrane to commonly occurring ions with a consequent Na-influx and a small Ca-influx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352766"}
{"pmid": "4352768", "title": "The effect of procaine hydrochloride and insulin on the cyclic AMP mediated responses in rat adipose tissue.", "content": "The effect of procaine hydrochloride and insulin on the cyclic AMP mediated responses in rat adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352768"}
{"pmid": "4352767", "title": "Effects of membrane depolarization on light scattering by cerebral cortical slices.", "content": "Effects of membrane depolarization on light scattering by cerebral cortical slices. 1. A system is described for simultaneously measuring the respiration and the reflectance of a tissue slice and is applied to a study of guinea-pig cerebral cortical slices.2. Reducing bathing medium osmolarity led to a reversible decrease in reflectance of these slices (as well as slices from liver and kidney cortex). In half isotonic solutions reflectance was reduced by 31%.3. Anoxia led to a decreased reflectance which was eliminated if all the Cl was substituted by the larger glucuronate anion.4. It is concluded that slice reflectance is lowered when cellular volumes are increased by water or isotonic solution influx.5. Membrane depolarization effected by ouabain, high (60 mM) K bathing medium, veratridine or repeated electrical pulses led to rapid decreases in reflectance of 25, 27, 31 and 7.5% respectively. Turning off the electrical pulses caused reflectance to return to control values. Reversibility of the chemical effectors was not tested.6. Substitution of Cl by glucuronate abolished the reflectance changes, although it did not inhibit the increased respiration induced by the depolarizing stimuli.7. Tetrodotoxin abolished both the respiratory and reflectance effects of veratridine and electrical pulses but had no effect upon those of high K or ouabain.8. The decrease in reflectance began about 1 sec after initiation of the pulses and was half maximal by 8 sec.9. Titrating reflectance against [K] showed that an increase of 5 mM-K led to a 4% decrease in reflectance and that reflectance became minimal between 60 and 80 mM-K(+).10. It is concluded that membrane depolarization in excitable cells of the cerebral cortex (and also, possibly, in the glia) causes rapid increases in cell volume due to influx of isotonic solution.11. The results indicate, more specifically, that changes in intercellular K concentrations of size and duration thought to occur following nervous activity in the C.N.S. cause cell volume changes large enough to drastically reduce the intercellular volumes and so, transiently, increase extracellular molecular and ionic concentrations. Increases of extracellular [K] and [Ca] have significant effects upon synaptic transmission and upon spontaneous nervous activity. It is suggested that nervous activity in one cell (or portion of it) might, in this way, strongly influence function in neighbouring elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352767"}
{"pmid": "4352770", "title": "The rabbit rectococcygeus, a smooth muscle preparation with an atropine-susceptible cholinergic motor transmission.", "content": "The rabbit rectococcygeus, a smooth muscle preparation with an atropine-susceptible cholinergic motor transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352770"}
{"pmid": "4352769", "title": "In vitro production of apolipoproteins in rat liver slices.", "content": "In vitro production of apolipoproteins in rat liver slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352769"}
{"pmid": "4352771", "title": "Adenoid cystic carcinoma of the trachea. Response to colbalt-60.", "content": "Adenoid cystic carcinoma of the trachea. Response to colbalt-60.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352771"}
{"pmid": "4352772", "title": "Carcinoembryonic antigen in patients with carcinoma of the lung.", "content": "Carcinoembryonic antigen in patients with carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352772"}
{"pmid": "4352775", "title": "Management of the acute burn patient--1973.", "content": "Management of the acute burn patient--1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352775"}
{"pmid": "4352776", "title": "The dependence of thoracic surgery on radiology.", "content": "The dependence of thoracic surgery on radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352776"}
{"pmid": "4352777", "title": "Virus-induced cholesterol crystals.", "content": "Virus-induced cholesterol crystals. One of the crystal types induced in cell cultures by a new feline herpesvirus was identified as cholesterol by crystal structure, polarized light microscopy, and mass spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352777"}
{"pmid": "4352778", "title": "Neurologic findings in retroperitoneal mass lesions.", "content": "Neurologic findings in retroperitoneal mass lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352778"}
{"pmid": "4352782", "title": "Pseudomonas endocarditis.", "content": "Pseudomonas endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352782"}
{"pmid": "4352783", "title": "Pancreatic islet cell carcinoma. I. Clinical features of 52 patients.", "content": "Pancreatic islet cell carcinoma. I. Clinical features of 52 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352783"}
{"pmid": "4352784", "title": "Pancreatic islet cell carcinoma. II. Results of therapy with streptozotocin in 52 patients.", "content": "Pancreatic islet cell carcinoma. II. Results of therapy with streptozotocin in 52 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352784"}
{"pmid": "4352785", "title": "Segmental renal-vein renin sampling for segmental renal infarction. Studies in a hypertensive patient.", "content": "Segmental renal-vein renin sampling for segmental renal infarction. Studies in a hypertensive patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352785"}
{"pmid": "4352787", "title": "Optic neuropathy of Graves disease, hyperthyroidism, and ocular myasthenia gravis.", "content": "Optic neuropathy of Graves disease, hyperthyroidism, and ocular myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352787"}
{"pmid": "4352788", "title": "Demonstration of a glucocorticoid hormone-receptor complex in the cytoplasm of a hormone-responsive tumour.", "content": "Demonstration of a glucocorticoid hormone-receptor complex in the cytoplasm of a hormone-responsive tumour. Specific substances binding [(3)H]-triamcinolone acetonide have been demonstrated in the cytoplasmic fraction of the R3230AC mammary carcinoma using sucrose gradient centrifugation. These receptors, which exhibit sedimentation coefficients of 8-9 Svedberg units, are relatively specific for glucocorticoid ligands and possess a high affinity for triamcinolone acetonide (K(d)∼7 × 10(-8) mol/1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352788"}
{"pmid": "4352789", "title": "The induction of tumours in the guinea-pig with methylcholanthrene and diethylnitrosamine and their propagation in vivo and in vitro.", "content": "The induction of tumours in the guinea-pig with methylcholanthrene and diethylnitrosamine and their propagation in vivo and in vitro. Tumour induction with diethylnitrosamine (DEN) and methylcholanthrene (MCA) has been studied in 3 strains of guinea-pig. A DEN concentration of 80 μg/ml drinking water daily proved too toxic but reasonable survival was obtained with 20 μg/ml 3 times per week in Hartley guinea-pigs and a local inbred strain. Heston Strain 13 guinea-pigs were particularly susceptible to the toxic effects of the diethylnitrosamine. In all3strains, 100% of the animals which survived the early toxic effects subsequently developed hepatomata, the mean time being 15 months. Methylcholanthrene was less toxic but more erratic as a carcinogen, the incidence of tumours in Hartley guinea-pigs varying from 18 to 100% in different experiments, the mean time of tumour development being 10 months.Three transplantable hepatomata and 3 transplantable sarcomata have been developed. The hepatomata are all predominantly hepatocellular carcinomata and the sarcomata comprise two liposarcomata and a fibrosarcoma. Successful shortterm primary cultures of hepatomata, sarcomata and of normal liver tissues have been accomplished. Established cell lines in tissue culture have been developed from one cholangiocarcinoma from an outbred guinea-pig and one transplanted hepatocellular carcinoma from an inbred guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352789"}
{"pmid": "4352790", "title": "Increased carcinogenic action of dimethylnitrosamine after prior administration of carbon tetrachloride.", "content": "Increased carcinogenic action of dimethylnitrosamine after prior administration of carbon tetrachloride. Rats were given a single dose of dimethylnitrosamine (DMN, 20 mg/kg body weight) alone or 42 or 60 hours after a non-lethal hepatotoxic dose of carbon tetrachloride (CC1(4)) and killed 12 months later. DMN alone produced no tumours in the kidney and a few in the liver, but when given 42 hours after CC1(4), tumours formed in the kidneys and the number in the liver was increased. When given after 60 hours, the incidence of kidney tumours was less but that of liver tumours was further increased. A larger dose of DMN (40 mg/kg) was tolerated 42 hours after CC1(4) and enhanced the number of kidney and liver tumours, the latter apparently due to an increased proportion of cholangiomata. Numerous small focal proliferations of atypical liver cells and of bile duct epithelium were observed after treatment with DMN. The incidence of these lesions in the different experimental treatments varied in a similar manner to the liver tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352790"}
{"pmid": "4352792", "title": "Cystathionine excess in children with hepatic cancer.", "content": "Cystathionine excess in children with hepatic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352792"}
{"pmid": "4352791", "title": "Inhibition of malignant cell invasion in vitro by a proteinase inhibitor.", "content": "Inhibition of malignant cell invasion in vitro by a proteinase inhibitor. The inhibitory effect of the protease inhibitor aprotinin (Trasylol) on the invasion of mouse kidney explants by polyoma virus transformed BHK21 cells was investigated using a mixed cell/organ culture technique. The extent of invasion was monitored by following the changes in LDH isoenzyme pattern in the explants and by histological assessment. The kidney explants containing aprotinin were found to maintain a normal kidney LDH pattern and to suffer considerably less invasion than the explants not containing the drug. These results support the idea that proteolytic enzymes are associated with invasion and that inhibitors of protease activity could possibly be useful in the management of clinical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352791"}
{"pmid": "4352793", "title": "Age- and sex-associated diethylnitrosamine dealkylation activity of the mouse liver and hepatocarcinogenesis.", "content": "Age- and sex-associated diethylnitrosamine dealkylation activity of the mouse liver and hepatocarcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352793"}
{"pmid": "4352794", "title": "Structural and functional changes in Novikoff hepatoma mitochondria.", "content": "Structural and functional changes in Novikoff hepatoma mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352794"}
{"pmid": "4352786", "title": "Viral disease of the labyrinth. II. An experimental model using mouse cytomegalovirus.", "content": "Viral disease of the labyrinth. II. An experimental model using mouse cytomegalovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352786"}
{"pmid": "4352795", "title": "Competitive RNA-DNA hybridization of nuclear and microsomal RNA during diethylnitrosamine hepatocarcinogenesis.", "content": "Competitive RNA-DNA hybridization of nuclear and microsomal RNA during diethylnitrosamine hepatocarcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352795"}
{"pmid": "4352796", "title": "Carcinogenesis by urethan via mother's milk and its enhancement of transplacental carcinogenesis in mice.", "content": "Carcinogenesis by urethan via mother's milk and its enhancement of transplacental carcinogenesis in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352796"}
{"pmid": "4352797", "title": "The metabolism and binding of testosterone in androgen-dependent and autonomous transplantable mouse mammary tumors.", "content": "The metabolism and binding of testosterone in androgen-dependent and autonomous transplantable mouse mammary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352797"}
{"pmid": "4352799", "title": "Specific antigens in human alveolar cell carcinoma.", "content": "Specific antigens in human alveolar cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352799"}
{"pmid": "4352798", "title": "Fine structure of primary liver tumors and tumor-bearing livers in man.", "content": "Fine structure of primary liver tumors and tumor-bearing livers in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352798"}
{"pmid": "4352800", "title": "Further observations on the effects of trypsin on the volume and functions of mitochondria isolated from normal liver and AH-130 Yoshida ascites hepatoma.", "content": "Further observations on the effects of trypsin on the volume and functions of mitochondria isolated from normal liver and AH-130 Yoshida ascites hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352800"}
{"pmid": "4352801", "title": "Modification of rabbit adrenal steroid biosynthesis by prolonged ACTH administration.", "content": "Modification of rabbit adrenal steroid biosynthesis by prolonged ACTH administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352801"}
{"pmid": "4352802", "title": "Adrenocortical control of catecholamine metabolism in the dog adrenal medulla: relationship to protein synthesis.", "content": "Adrenocortical control of catecholamine metabolism in the dog adrenal medulla: relationship to protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352802"}
{"pmid": "4352803", "title": "Reversible inhibition of ACTH-induced corticosteroid release by cycloheximide: evidence for an unidentified cellular messenger.", "content": "Reversible inhibition of ACTH-induced corticosteroid release by cycloheximide: evidence for an unidentified cellular messenger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352803"}
{"pmid": "4352804", "title": "Dynamics of insulin release by perfused rat pancreases: effects of hypophysectomy, growth hormone, adrenocorticotropic hormone, and hydrocortisone.", "content": "Dynamics of insulin release by perfused rat pancreases: effects of hypophysectomy, growth hormone, adrenocorticotropic hormone, and hydrocortisone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352804"}
{"pmid": "4352805", "title": "Thyrotropin releasing hormone (TRH): neurotransmitter regulation of secretion by mouse hypothalamic tissue in vitro.", "content": "Thyrotropin releasing hormone (TRH): neurotransmitter regulation of secretion by mouse hypothalamic tissue in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352805"}
{"pmid": "4352807", "title": "Regulation of steroidogenesis by ACTH in a superfusion system for isolated adrenal cells.", "content": "Regulation of steroidogenesis by ACTH in a superfusion system for isolated adrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352807"}
{"pmid": "4352806", "title": "Indomethacin, lipolysis, and cyclic AMP accumulation in white fat cells.", "content": "Indomethacin, lipolysis, and cyclic AMP accumulation in white fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352806"}
{"pmid": "4352808", "title": "Nuclear receptor estrogen complex: accumulation, retention and localization in the hypothalamus and pituitary.", "content": "Nuclear receptor estrogen complex: accumulation, retention and localization in the hypothalamus and pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352808"}
{"pmid": "4352809", "title": "Vitamin D and intestinal transport of calcium: effects of prednisolone.", "content": "Vitamin D and intestinal transport of calcium: effects of prednisolone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352809"}
{"pmid": "4352811", "title": "Effects of estrogens on renin substrate and uterine weights in rats.", "content": "Effects of estrogens on renin substrate and uterine weights in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352811"}
{"pmid": "4352810", "title": "The gonadotropin-primed rat: a model for testing agents that influence steroid biosynthesis.", "content": "The gonadotropin-primed rat: a model for testing agents that influence steroid biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352810"}
{"pmid": "4352812", "title": "The chest roentgenogram in babies of 1000 grams or less.", "content": "The chest roentgenogram in babies of 1000 grams or less.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352812"}
{"pmid": "4352813", "title": "Desquamative interstitial pneumonia: progression to the end-stage lung and the unusual complication of alveolar cell carcinoma: case report.", "content": "Desquamative interstitial pneumonia: progression to the end-stage lung and the unusual complication of alveolar cell carcinoma: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352813"}
{"pmid": "4352814", "title": "The activation of coagulation by extracts of mucus: a possible pathway of intravascular coagulation accompanying adenocarcinomas.", "content": "The activation of coagulation by extracts of mucus: a possible pathway of intravascular coagulation accompanying adenocarcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352814"}
{"pmid": "4352815", "title": "The actions of penicillin and other antibiotics on bacterial cell wall synthesis.", "content": "The actions of penicillin and other antibiotics on bacterial cell wall synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352815"}
{"pmid": "4352821", "title": "Lateral inhibition and cognitive masking: a neuropsychological theory of attention.", "content": "Lateral inhibition and cognitive masking: a neuropsychological theory of attention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352821"}
{"pmid": "4352823", "title": "Arteriographic demonstration of two islet-cell tumors in a patient with Zollinger-Ellison syndrome.", "content": "Arteriographic demonstration of two islet-cell tumors in a patient with Zollinger-Ellison syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352823"}
{"pmid": "4352824", "title": "Urinary excretion of cyclic adenosine monophosphate in the detection and diagnosis of primary hyperparathyroidism.", "content": "Urinary excretion of cyclic adenosine monophosphate in the detection and diagnosis of primary hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352824"}
{"pmid": "4352826", "title": "Bilateral carcinoma of the breast.", "content": "Bilateral carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352826"}
{"pmid": "4352829", "title": "Genetic regulatory systems in Neurospora.", "content": "Genetic regulatory systems in Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352829"}
{"pmid": "4352831", "title": "The genetics of transmissible plasmids.", "content": "The genetics of transmissible plasmids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352831"}
{"pmid": "4352830", "title": "The operon revisited.", "content": "The operon revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352830"}
{"pmid": "4352834", "title": "Confirmation of the 1-20 amino acid sequence of human adrenocorticotrophin.", "content": "Confirmation of the 1-20 amino acid sequence of human adrenocorticotrophin. The tryptic fragments of natural human adrenocorticotrophin, were separated by countercurrent distribution and a correction in positions 25, 26, 27 and 30 was made by Riniker et al. (1972) in a study of the fragment containing residues 22-39. We have purified the remaining tryptic fragments, namely residues 1-8, 9-15, 16-21 and 17-21, by using ion-exchange chromatography on CM-cellulose and have carried out sequence determination by using the subtractive Edman degradation procedure and digestion with aminopeptidase M and carboxypeptidase B. These results have confirmed the proposed sequence for human adrenocorticotrophin in regions 6-7, 10-14 and 17-20, which had previously been arrived at only by analogy with the invariant sequence found in the three other mammalian adrenocorticotrophin species that had been investigated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352834"}
{"pmid": "4352833", "title": "The effects of glucagon and insulin on adenosine 3':5'-cyclic monophosphate concentrations in an organ culture of mature rat liver.", "content": "The effects of glucagon and insulin on adenosine 3':5'-cyclic monophosphate concentrations in an organ culture of mature rat liver. 1. A modified radioimmunoassay for cyclic AMP was developed from the method of Steiner et al. (1969). Cyclic [(3)H]AMP was used as the radioactive tracer. Free and antibody-bound nucleotides were separated by adsorption of protein to Millipore filters. The assay was used to measure amounts of cyclic AMP down to 0.1pmol in 50mul. 2. The effect of glucagon on cyclic AMP content in pieces of mature rat liver maintained for 6 days in organ culture was studied. 3. Cyclic AMP content in the tissue reached a maximum in 5-15min and then decreased. This may have been partly due to an inhibitor of glucagon action formed in the tissue. Small amounts of cyclic AMP were released into the incubation medium. 4. The maximal increase in cyclic AMP content produced by glucagon decreased over 6 days in culture. However, liver pieces cultured for 2 and 6 days were more sensitive to low concentrations of glucagon than were fresh liver pieces. Glucagon concentrations for half-maximal effects were approx. 1mum and 0.05mum for fresh liver and 2-day cultured liver respectively. 5. Insulin (3.5mum) lowered the cyclic AMP content by 30% in the presence of a submaximal glucagon concentration in liver cultured for 2 days. No effect of insulin was demonstrated on fresh liver pieces. 6. Insulin and glucagon were rapidly destroyed by fresh liver pieces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352833"}
{"pmid": "4352835", "title": "D-3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Kinetic mechanism from steady-state kinetics of the reaction catalysed by the enzyme in solution and covalently attached to diethylaminoethylcellulose.", "content": "D-3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Kinetic mechanism from steady-state kinetics of the reaction catalysed by the enzyme in solution and covalently attached to diethylaminoethylcellulose. 1. The reversible NAD(+)-linked oxidation of d-3-hydroxybutyrate to acetoacetate in 0.1m-sodium pyrophosphate buffer, pH8.5, at 25.0 degrees C, catalysed by d-3-hydroxybutyrate dehydrogenase (d-3-hydroxybutyrate-NAD(+) oxidoreductase, EC 1.1.1.30), was studied by initial-velocity, dead-end inhibition and product-inhibition analysis. 2. The reactions were carried out on (a) the soluble enzyme from Rhodopseudomonas spheroides and (b) an insoluble derivative of this enzyme prepared by its covalent attachment to DEAE-cellulose by using 2-amino-4,6-dichloro-s-triazine as coupling agent. 3. The insolubilized enzyme preparation contained 5mg of protein/g wet wt. of total material, and when freshly prepared its specific activity was 1.2mumol/min per mg of protein, which is 67% of that of the soluble dialysed enzyme. 4. The reactions catalysed by both the enzyme in solution and the insolubilized enzyme were shown to follow sequential pathways in which the nicotinamide nucleotides bind obligatorily first to the enzyme. Evidence is presented for kinetically significant ternary complexes and that the rate-limiting step(s) of both catalyses probably involves isomerization of the enzyme-nicotinamide nucleotide complexes and/or dissociation of the nicotinamide nucleotides from the enzyme. Both catalyses therefore are probably best described as ordered Bi Bi mechanisms, possibly with multiple enzyme-nicotinamide nucleotide complexes. 5. The kinetic parameters and the calculable rate constants for the catalysis by the soluble enzyme are similar to the corresponding parameters and rate constants for the catalysis by the insolubilized enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352835"}
{"pmid": "4352836", "title": "D-3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Kinetics of radioisotope redistribution at chemical equilibrium catalysed by the enzyme in solutions.", "content": "D-3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Kinetics of radioisotope redistribution at chemical equilibrium catalysed by the enzyme in solutions. 1. The reversible NAD(+)-linked oxidation of d-3-hydroxybutyrate to acetoacetate in 0.1m-sodium pyrophosphate buffer, pH8.5, at 25.0 degrees C, catalysed by d-3-hydroxybutyrate dehydrogenase (d-3-hydroxybutyrate-NAD(+) oxidoreductase, EC 1.1.1.30), was studied kinetically at chemical equilibrium by monitoring radioisotope redistribution with sodium dl-hydroxy[3-(14)C]butyrate and [4-(3)H]NAD(+)(labelled in the nicotinamide ring). 2. When all substrates are maintained at concentrations approaching saturation (approx. 3-50 times the K(m) values) the first-order rate constant for the enzyme-catalysed interconversion of NAD(+) and NADH is much smaller than that for the enzyme-catalysed interconversion of d-3-hydroxybutyrate and acetoacetate. 3. The rate of interconversion of NAD(+) and NADH increases initially with increasing concentrations of d-3-hydroxybutyrate and acetoacetate (ratio of concentrations maintained constant), passes through a maximum and approaches closely to zero at saturating concentrations of the latter substrates. 4. The rates of interconversion of NAD(+) and NADH and of d-3-hydroxybutyrate and acetoacetate increase with increasing concentration of NAD(+) (up to 66 times its K(m) value) and NADH (up to 180 times its K(m) value) (ratio of the concentrations of the nicotinamide nucleotides maintained constant). 5. These findings support the description of this catalysis as an ordered Bi Bi mechanism with no detectable alternative pathway, in which the interconversion of the central ternary complexes is not rate-limiting, and provide no evidence for the formation of dead-end complexes. 6. The solubility of 2,4-dinitrophenylhydrazine in HCl exhibits an acidity optimum, the maximum solubility at 25.0 degrees C (3.8mg/ml, 19mm) occurring at 2.29m-HCl; in solutions of this acidity acetone 2,4-dinitrophenylhydrazone is relatively insoluble (0.098mg/ml, 0.413mm).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352836"}
{"pmid": "4352837", "title": "The effect of modifying lysine-126 on the physical, catalytic and regulatory properties of bovine liver glutamate dehydrogenase.", "content": "The effect of modifying lysine-126 on the physical, catalytic and regulatory properties of bovine liver glutamate dehydrogenase. 1. The reaction of 4-iodoacetamidosalicylate with bovine liver glutamate dehydrogenase is dependent on pH. The pH-activity curve is bell-shaped and can be described by apparent pK values of 7.8+/-0.2 and 9.1+/-0.2. 2. Enzyme in which lysine-126 has been modified by 4-iodoacetamidosalicylate has unaltered sedimentation characteristics except when measured in the presence of GTP and NADH. 3. GTP binding to the inhibited enzyme is unaltered. However, GTP can no longer promote the binding of a second molecule of NADH, since this is already bound to the inhibited enzyme without GTP. 4. The equilibrium binding of ADP, GTP, NAD-sulphite and NADH (when measured at low concentrations) was largely unchanged by modification. 5. The number of binding sites for 2-oxoglutarate to the enzyme-NADH complex were decreased by 60% in an enzyme that has been inhibited by 70%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352837"}
{"pmid": "4352838", "title": "The reaction of a histidine residue in glutamate dehydrogenase with diethyl pyrocarbonate.", "content": "The reaction of a histidine residue in glutamate dehydrogenase with diethyl pyrocarbonate. 1. One mol of diethyl pyrocarbonate will react with one mol of glutamate dehydrogenase polypeptide chains to form one mol of N(1)-carbethoxyhistidine. Reaction is prevented by NADH. 2. The 1:1 complex has an increased specific activity (1.4-2.0-fold). 3. The reason for the activation is discussed. The results are not consistent with NADH dissociation from the enzyme-glutamate-NADH complex being rate-limiting in the steady state measured. 4. The effects of modification on the properties of the enzyme were investigated. The effects of GTP and NAD(+) on the enzyme activity are unaltered by activation. NADH binding is unaltered and there is no apparent change in the molecular weight. However, the activated enzyme can still be further activated by ADP. K(s) for ADP is decreased fivefold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352838"}
{"pmid": "4352841", "title": "\"If a man have a strong faith\".", "content": "\"If a man have a strong faith\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352841"}
{"pmid": "4352842", "title": "Excitation-contraction coupling in heart. IX. Changes in the intracellular stores of calcium in failing hearts due to lack of substrate and oxygen.", "content": "Excitation-contraction coupling in heart. IX. Changes in the intracellular stores of calcium in failing hearts due to lack of substrate and oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352842"}
{"pmid": "4352843", "title": "Effect of cyclic 3',5'-AMP on the (Na+K)-ATPase of myocardial sarcolemma.", "content": "Effect of cyclic 3',5'-AMP on the (Na+K)-ATPase of myocardial sarcolemma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352843"}
{"pmid": "4352844", "title": "Evaluation of a rapid competitive protein binding assay for progesterone in pregnancy and some of its complications.", "content": "Evaluation of a rapid competitive protein binding assay for progesterone in pregnancy and some of its complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352844"}
{"pmid": "4352846", "title": "Location of heme a in cytochrome a. I. Combination of alkyl isonitriles with cytochrome a.", "content": "Location of heme a in cytochrome a. I. Combination of alkyl isonitriles with cytochrome a.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352846"}
{"pmid": "4352847", "title": "Kinetic studies on hydrogenase. Parahydrogen-orthohydrogen conversion and hydrogen-deuterium exchange reactions.", "content": "Kinetic studies on hydrogenase. Parahydrogen-orthohydrogen conversion and hydrogen-deuterium exchange reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352847"}
{"pmid": "4352855", "title": "L-amino acid oxidase, phosphodiesterase, total protein and other properties of juvenile timber rattlesnake (C. H. horridus) venom at different stages of growth.", "content": "L-amino acid oxidase, phosphodiesterase, total protein and other properties of juvenile timber rattlesnake (C. H. horridus) venom at different stages of growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352855"}
{"pmid": "4352856", "title": "Hypersensitivity to different ACTH peptides.", "content": "Hypersensitivity to different ACTH peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352856"}
{"pmid": "4352858", "title": "Evolution of cytochrome C molecule.", "content": "Evolution of cytochrome C molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352858"}
{"pmid": "4352859", "title": "Actions of transmitter substances on the neuromuscular junctions of vertebrates and invertebrates.", "content": "Actions of transmitter substances on the neuromuscular junctions of vertebrates and invertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352859"}
{"pmid": "4352857", "title": "Suprailiac lymphography.", "content": "Suprailiac lymphography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352857"}
{"pmid": "4352864", "title": "Partial reactions of D-glucose 6-phosphate-1L-myoinositiol 1-phosphate cyclase.", "content": "Partial reactions of D-glucose 6-phosphate-1L-myoinositiol 1-phosphate cyclase. After removal of tightly bound NAD(+) by using charcoal, a preparation of d-glucose 6-phosphate-1 l-myoinositol 1-phosphate cyclase catalysed the reduction of 5-keto-d-glucitol 6-phosphate and 5-keto-d-glucose 6-phosphate by [4-(3)H]NADH to give [5-(3)H]-glucitol 6-phosphate and [5-(3)H]glucose 6-phosphate respectively. The position of the tritium atom in the latter was shown by degradation. Both enzyme-catalysed reductions were strongly inhibited by 2-deoxy-d-glucose 6-phosphate, a powerful competitive inhibitor of inositol cyclase. The charcoal-treated enzyme preparation also converted 5-keto-d-glucose 6-phosphate into [(3)H]myoinositol 1-phosphate in the presence of [4-(3)H]NADH, but less effectively. These partial reactions of inositol cyclase are interpreted as providing strong evidence for the formation of 5-keto-d-glucose 6-phosphate as an enzyme-bound intermediate in the conversion of d-glucose 6-phosphate into 1 l-myoinositol 1-phosphate. The enzyme was partially inactivated by NaBH(4) in the presence of NAD(+). Glucose 6-phosphate did not increase the inactivation, and there was no inactivation in the absence of NAD(+). There was no evidence for Schiff base formation during the cyclization. d-Glucitol 6-phosphate (l-sorbitol 1-phosphate) was a good inhibitor of the overall reaction. It did not inactivate the enzyme. The apparent molecular weight of inositol cyclase as determined by Sephadex chromatography was 2.15x10(5).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352864"}
{"pmid": "4352865", "title": "Kinetic properties of the partially purified pyruvate dehydrogenase complex of ox brain.", "content": "Kinetic properties of the partially purified pyruvate dehydrogenase complex of ox brain. The properties of a purified preparation of the pyruvate dehydrogenase complex from ox brain have been compared with those of a similar preparation from ox kidney. A broad pH optimum around 7.8, similar dependence on ionic strength, and independence of the nature of the buffer anions or cations characterized preparations from both tissues. Michaelis constants for the binding of pyruvate, thiamin pyrophosphate, NAD(+) and CoA were also similar. Enzyme from both tissues was inhibited by NADH, by copper and other heavy metals, by high concentrations of tricarboxylic acid-cycle intermediates, and by preincubation with ATP. Acetyl-CoA itself did not appear to inhibit these preparations, although some commercial preparations of acetyl-CoA did contain an inhibitor. Although oxaloacetate and alpha-oxobutyrate were weak inhibitors, a number of other alpha-oxo acids including phenylpyruvate did not inhibit. The properties of the pyruvate dehydrogenase complex from brain and kidney appeared similar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352865"}
{"pmid": "4352866", "title": "The significance of abrupt transitions in Lineweaver-Burk plots with particular reference to glutamate dehydrogenase. Negative and positive co-operativity in catalytic rate constants.", "content": "The significance of abrupt transitions in Lineweaver-Burk plots with particular reference to glutamate dehydrogenase. Negative and positive co-operativity in catalytic rate constants. 1. Lineweaver-Burk plots for glutamate dehydrogenase, glucose 6-phosphate dehydrogenase and several other enzymes show one or more abrupt transitions between apparently linear sections. These transitions correspond to abrupt increases in the apparent K(m) and V(max.) with increasing concentration of the varied substrate. 2. The generalized reciprocal initial-rate equation for a multi-site enzyme requires several restrictions to be put on it in order to generate such plots. These mathematical conditions are explored. 3. It is shown that the effective omission of a term in the denominator of the reciprocal initial-rate equation represents a minimal requirement for generation of abrupt transitions. This corresponds in physical terms to negative co-operativity followed by positive co-operativity affecting the catalytic rate constant for the reaction. 4. Previous models for glutamate dehydrogenase cannot adequately account for the results. On the other hand, the model based on both negative and positive co-operativity gives a good fit to the experimental points. 5. The conclusions are discussed in relation to current knowledge of the structure and mechanism of glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352866"}
{"pmid": "4352868", "title": "Inhibition of functional vasodilatation and prostaglandin formation in rabbit adipose tissue by indomethacin and aspirin.", "content": "Inhibition of functional vasodilatation and prostaglandin formation in rabbit adipose tissue by indomethacin and aspirin. 1. The epigastric adipose depot of rabbits has been used to examine the effect of indomethacin, aspirin and nicotinic acid on the free fatty acid release and blood flow in fat tissue.2. The prostaglandin formation which occurs in adipose tissue during lipolysis is prevented by indomethacin and aspirin. The corresponding functional vasodilatation which occurs after infusions of lipolytic substances is also abolished by these two anti-inflammatory compounds.3. This finding is consistent with the theory that prostaglandin E(2) is the mediator of functional vasodilatation in adipose tissue.4. Nicotinic acid sometimes inhibits the release of free fatty acids from adipose tissue by preventing activation of the tissue lipase. In those experiments in which this inhibition occurred, the vasodilatation was also prevented.5. This finding is consistent with the view that the prostaglandin E(2) which mediates the functional vasodilatation, originates in the triglycerides of the fat tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352868"}
{"pmid": "4352867", "title": "The release of spasmogenic substances from human chopped lung tissue and its inhibition.", "content": "The release of spasmogenic substances from human chopped lung tissue and its inhibition. 1. Human lung tissue, passively sensitized with reaginic antibodies, released prostaglandins E(1), E(2) and F(2alpha) in addition to histamine and slow reacting substance (SRS-A), when exposed to the appropriate antigen. No rabbit aorta contracting substance (RCS) was detected.2. Experiments with rats and guinea-pigs showed that the release of RCS is not confined to anaphylactic reactions mediated by non-reaginic antibodies but may be a feature of anaphylaxis in guinea-pigs alone.3. Human lung tissue gently agitated with a blunt nylon rod liberated an E-type prostaglandin and RCS in addition to histamine and SRS-A.4. Human isolated bronchial muscle was contracted by RCS.5. Disodium cromoglycate antagonized the release of prostaglandins during anaphylaxis but not during agitation of human lung tissue, whereas indomethacin blocked the release of prostaglandins during agitation and anaphylaxis.6. The release of an E-type prostaglandin during anaphylaxis in human lung tissue, which inhibits the further release of histamine could be another example of the regulatory role of prostaglandins in body functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352867"}
{"pmid": "4352869", "title": "Effects of angiotensin, catecholamines and cyclic AMP on calcium storage in aortic microsomes.", "content": "Effects of angiotensin, catecholamines and cyclic AMP on calcium storage in aortic microsomes. 1. The binding of calcium observed in microsomal membranes derived from the intimal-medial layer of rabbit aorta was specifically increased by the magnesium salt of adenosine triphosphate (Mg-ATP). This calcium uptake was inhibited by potassium and sodium.2. Angiotensin II, both in the presence and in the absence of Mg-ATP, reduced the binding of calcium and increased the release of membrane-incorporated calcium. These effects were dose-dependent. Analogues of angiotensin II devoid of intrinsic activity, failed to alter the release of calcium.3. Dibutyryl-cyclic AMP increased the binding of calcium and reduced the rate of its release. The maximal effect was observed at the concentration of 10(-5)M.4. (-)-Noradrenaline reduced the binding of calcium; this effect was inhibited by phenoxybenzamine. Conversely, adrenaline like cyclic AMP, increased the calcium binding; the effect of adrenaline was suppressed by a beta-adrenoceptor blocking agent.5. These observations demonstrate the existence of membranes in rabbit aorta capable of storing calcium. Excitatory drugs seem to affect directly and specifically the binding and release of calcium in these membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352869"}
{"pmid": "4352870", "title": "Action of botulinum toxin on transmission from sympathetic nerves to the vas deferens.", "content": "Action of botulinum toxin on transmission from sympathetic nerves to the vas deferens. Botulinum toxin (Type A) depressed or abolished transmission from postganglionic nerves to smooth muscle of isolated preparations of guinea-pig and mouse vas deferens. The time course of blockade was 2 to 6 times slower than that observed with the same concentration of the same batch of toxin on the rat diaphragm. Spontaneous excitatory junction potentials were still observed after 7 h exposure, indicating that the smooth muscle membrane was still able to respond to noradrenaline. Depression of transmission is probably due to a presynaptic action of unknown nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352870"}
{"pmid": "4352871", "title": "Indolealkylamine nerve terminals in cerebral ventricles: identification by electron microscopy and fluorescence histochemistry.", "content": "Indolealkylamine nerve terminals in cerebral ventricles: identification by electron microscopy and fluorescence histochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352871"}
{"pmid": "4352872", "title": "Corticosterone binding to hippocampus: nuclear and cytosol binding in vitro.", "content": "Corticosterone binding to hippocampus: nuclear and cytosol binding in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352872"}
{"pmid": "4352874", "title": "Inhibition and excitation of units in paraventricular nucleus after stimulation of the septum, amygdala and neurohypophysis.", "content": "Inhibition and excitation of units in paraventricular nucleus after stimulation of the septum, amygdala and neurohypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352874"}
{"pmid": "4352873", "title": "Properties of corticosterone-binding macromolecules from rat brain cytosol.", "content": "Properties of corticosterone-binding macromolecules from rat brain cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352873"}
{"pmid": "4352876", "title": "Post mortem characteristics of the hepatic microsomal drug oxidising enzyme system.", "content": "Post mortem characteristics of the hepatic microsomal drug oxidising enzyme system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352876"}
{"pmid": "4352877", "title": "The mechanism of action of aflatoxin B1 on protein synthesis: observations on malignant viral transformed and untransformed cells in culture.", "content": "The mechanism of action of aflatoxin B1 on protein synthesis: observations on malignant viral transformed and untransformed cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352877"}
{"pmid": "4352878", "title": "A new synthesis of furanoid fatty acids: isomerisation of hydroxy-cis-enynoic acids by alkali, and on argentous silica gel.", "content": "A new synthesis of furanoid fatty acids: isomerisation of hydroxy-cis-enynoic acids by alkali, and on argentous silica gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352878"}
{"pmid": "4352879", "title": "Early reciprocal inhibition in athetosis.", "content": "Early reciprocal inhibition in athetosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352879"}
{"pmid": "4352881", "title": "Metabolism of NAD after whole-body irradiation. IV. Incorporation of nicotinamide by isolated perfused liver and by intact rats.", "content": "Metabolism of NAD after whole-body irradiation. IV. Incorporation of nicotinamide by isolated perfused liver and by intact rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352881"}
{"pmid": "4352887", "title": "Pituitary peptide.", "content": "Pituitary peptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352887"}
{"pmid": "4352888", "title": "Characterization of murine leukaemia virus-specific DNA present in normal mouse cells.", "content": "Characterization of murine leukaemia virus-specific DNA present in normal mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352888"}
{"pmid": "4352889", "title": "Similar growth of Chinese hamster cells in the presence of phenethyl alcohol or dibutyryl cyclic AMP.", "content": "Similar growth of Chinese hamster cells in the presence of phenethyl alcohol or dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352889"}
{"pmid": "4352890", "title": "Fucose-containing glycopeptides from the cell surface of Chinese hamster ovary cells grown in the presence or absence of cyclic AMP.", "content": "Fucose-containing glycopeptides from the cell surface of Chinese hamster ovary cells grown in the presence or absence of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352890"}
{"pmid": "4352891", "title": "The role of calcium in insulin secretion.", "content": "The role of calcium in insulin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352891"}
{"pmid": "4352896", "title": "Subclinical peripheral nerve involvement in unilateral Bell's palsy.", "content": "Subclinical peripheral nerve involvement in unilateral Bell's palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352896"}
{"pmid": "4352897", "title": "Aerobic and anaerobic energy metabolism in compensatory renal hypertrophy.", "content": "Aerobic and anaerobic energy metabolism in compensatory renal hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352897"}
{"pmid": "4352895", "title": "The gonadotropin receptor of the human corpus luteum.", "content": "The gonadotropin receptor of the human corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352895"}
{"pmid": "4352898", "title": "Influence of cadmium ions on contractile response of isolated aortas to stimulatory agents.", "content": "Influence of cadmium ions on contractile response of isolated aortas to stimulatory agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352898"}
{"pmid": "4352899", "title": "Coupled sodium-chloride influx across the brush border of rabbit ileum.", "content": "Coupled sodium-chloride influx across the brush border of rabbit ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352899"}
{"pmid": "4352900", "title": "Sodium dependence of base-line and ADH-stimulated short-circuit current in toad bladder.", "content": "Sodium dependence of base-line and ADH-stimulated short-circuit current in toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352900"}
{"pmid": "4352901", "title": "Carcinoma of the hepatic ducts: review of 11 cases.", "content": "Carcinoma of the hepatic ducts: review of 11 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352901"}
{"pmid": "4352902", "title": "Inherited constriction fragility of chromosome 2.", "content": "Inherited constriction fragility of chromosome 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352902"}
{"pmid": "4352903", "title": "The effect of a lipid-rich diet on the properties and composition of lipoprotein particles from the Golgi apparatus of guinea-pig liver.", "content": "The effect of a lipid-rich diet on the properties and composition of lipoprotein particles from the Golgi apparatus of guinea-pig liver. 1. A cell fraction rich in Golgi apparatus was isolated from the livers of guinea pigs fed on a lipid-rich diet (1.6% cholesterol, 15% corn oil). 2. The Golgi cisternae and secretory vesicles contained electron-dense particles which were tentatively identified as VLD (very-low-density) and LD (low-density) lipoproteins. Particles of moderate electron density, 150-500nm in diameter, were seen associated with membranous elements of the Golgi-apparatus cell fraction. Disruption of this cell fraction permitted the release of these three species of particles, which were separated into particulate lipid, and VLD and LD lipoproteins. 3. The large particles of moderate electron density, isolated as particulate lipid, were distinct from both species of Golgi particles in their chemical composition and in possessing an immunochemically unreactive apolipoprotein(s). Morphological observations suggest that the particulate lipid arose from cytoplasmic lipid droplets which were present as contaminants of the Golgi-rich fraction. 4. The chemical and immunochemical results are consistent with the suggestion that the Golgi LD particles are precursors of the VLD particles, into which they may be transformed by the addition of both triglyceride and cholesteryl ester. The present results provide further support for the proposal that the Golgi VLD particles are precursors of the serum VLD lipoproteins in the guinea pig. 5. Hepatic Golgi VLD particles isolated from guinea pigs fed on the lipid-rich diet contained significantly higher molar amounts (relative to protein) of both cholesteryl ester and triglyceride than similar particles from animals fed on a normal diet. These results suggest that the type of Golgi VLD particle produced from the LD particle is a direct consequence of the amount and composition of the dietary lipid. 6. Hepatic Golgi LD particles isolated from guinea pigs fed on different diets were similar in chemical composition and contained approx. 50% by weight of phospholipid. We conclude that the Golgi LD particle is normally present in the Golgi-apparatus cell fraction from guinea-pig liver, and may represent the end product of lipoprotein biosynthesis in the smooth endoplasmic reticulum. 7. The serum LD lipoproteins and Golgi LD particles were quite distinct in chemical composition. However, these two lipoprotein species were immunochemically identical and exhibited a similar range of flotation rate. It appears unlikely that the Golgi LD particles are secreted as the precursors of the serum LD lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352903"}
{"pmid": "4352905", "title": "The amino acid sequence of cytochrome c from Allium porrum L. (leek).", "content": "The amino acid sequence of cytochrome c from Allium porrum L. (leek). The amino acid sequence of leek cytochrome c was determined with 0.4mumol of protein. The sequence was deduced solely from a chymotryptic digest. The cytochrome was homologous with other plant cytochromes c of mitochondrial origin. Leek cytochrome c has an N-acetylated ;tail' as compared with mammalian cytochrome c, and two residues of epsilon-N-trimethyl-lysine. Unlike other plant cytochromes c, leek cytochrome c has glutamic acid or glutamine in position 11, leucine in position 20 and alanine in position 51. 4-Hydroxyproline partially substitutes for proline in position 79. Experimental details are given in a supplementary paper that has been deposited as Supplementary Publication SUP 50012, at the National Lending Library for Science and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1973) 131, 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352905"}
{"pmid": "4352906", "title": "The amino acid sequence of cytochrome c from Spinacea oleracea L. (spinach).", "content": "The amino acid sequence of cytochrome c from Spinacea oleracea L. (spinach). The amino acid sequence of spinach (Spinacea oleracea L., var. Monster Viroflay) cytochrome c was determined on 1mumol of protein. The molecule consists of 111 residues and is homologous with other mitochondrial cytochromes c. Experimental details are given in a supplementary paper that has been deposited as Supplementary Publication SUP 50013, at the National Lending Library for Science and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1973), 131, 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352906"}
{"pmid": "4352904", "title": "Milk xanthine oxidase type D (dehydrogenase) and type O (oxidase). Purification, interconversion and some properties.", "content": "Milk xanthine oxidase type D (dehydrogenase) and type O (oxidase). Purification, interconversion and some properties. 1. The xanthine oxidase of cow's milk, crude or purified, appears as an oxidase (type O), and can be converted almost completely into a NAD(+)-dependent dehydrogenase (type D) by treatment with dithioerythritol or dihydrolipoic acid, but only to a small extent by other thiols. 2. The D form of the enzyme is inhibited by NADH, which competes with NAD(+). 3. The kinetic constants of the two forms of the enzyme are similar to those of the corresponding forms of rat liver xanthine oxidase. 4. Milk xanthine oxidase is converted into an irreversible O form by pretreatment with chymotrypsin, papain or subtilisin, but only partially with trypsin. 5. The enzyme as purified shows a major faster band and a minor slower band on gel electrophoresis. The slower band is greatly reinforced after xanthine oxidase is converted into the irreversible O form by chymotrypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352904"}
{"pmid": "4352907", "title": "The preparation and analysis of a new trinucleotide from yeast ribonucleic acid, containing two adjacent 2'-O-methylpentose residues.", "content": "The preparation and analysis of a new trinucleotide from yeast ribonucleic acid, containing two adjacent 2'-O-methylpentose residues. Quantities of the order of 10mg of three alkali-stable trinucleotides were prepared from yeast ribonucleic acid. Analyses showed that they were of the type N1m-N2m-N3p, where m signifies 2'-O-methylation of the pentose residue. One, Am-Um-Gp, is newly described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352907"}
{"pmid": "4352908", "title": "A study of the kinetics and mechanism of yeast alcohol dehydrogenase with a variety of substrates.", "content": "A study of the kinetics and mechanism of yeast alcohol dehydrogenase with a variety of substrates. 1. The kinetics of oxidation of ethanol, propan-1-ol, butan-1-ol and propan-2-ol by NAD(+) and of reduction of acetaldehyde and butyraldehyde by NADH catalysed by yeast alcohol dehydrogenase were studied. 2. Results for the aldehyde-NADH reactions are consistent with a compulsory-order mechanism with the rate-limiting step being the dissociation of the product enzyme-NAD(+) complex. In contrast the results for the alcohol-NAD(+) reactions indicate that some dissociation of coenzyme from the active enzyme-NAD(+)-alcohol ternary complexes must occur and that the mechanism is not strictly compulsory-order. The rate-limiting step in ethanol oxidation is the dissociation of the product enzyme-NADH complex but with the other alcohols it is probably the catalytic interconversion of ternary complexes. 3. The rate constants describing the combination of NAD(+) and NADH with the enzyme and the dissociations of these coenzymes from binary complexes with the enzyme were measured.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352908"}
{"pmid": "4352910", "title": "Interaction between polyuridylic acid and rabbit globin messenger ribonucleic acid.", "content": "Interaction between polyuridylic acid and rabbit globin messenger ribonucleic acid. Poly(U) binds to globin mRNA in 0.1m-NaCl. Studies with ribonuclease digestion of this complex suggest that there are polyadenylate-rich sequences in the mRNA containing about 30-40 adenylate residues. The sequences appear to be homogenous and of approximately the same length for both alpha- and beta-globin mRNA. They are most likely located at the 3' terminus of the molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352910"}
{"pmid": "4352909", "title": "Protein kinase activity in commercially available crystalline yeast alcohol dehydrogenase.", "content": "Protein kinase activity in commercially available crystalline yeast alcohol dehydrogenase. Commercially available crystalline yeast alcohol dehydrogenase contained protein kinase activity. Casein and phosvitin were readily phosphorylated, but whole calf thymus histone was not. The protein kinase activity was inhibited by KCl, was not stimulated by cyclic AMP and could be separated from the alcohol dehydrogenase activity by sucrose density centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352909"}
{"pmid": "4352911", "title": "The inhibition of pig kidney alkaline phosphatase by oxidized or reduced nicotinamide-adenine dinucleotide and related compounds.", "content": "The inhibition of pig kidney alkaline phosphatase by oxidized or reduced nicotinamide-adenine dinucleotide and related compounds. 1. The inhibition of alkaline phosphatase by NAD(+), NADH, adenosine and nicotinamide was studied. 2. All of these substances except NAD(+) act as uncompetitive inhibitors, i.e. double-reciprocal plots are parallel. NAD(+), however, is a ;mixed' inhibitor of alkaline phosphatase and is less potent than NADH. 3. Inhibition studies with pairs of the inhibitors suggest that, in spite of the difference in type of inhibition, NAD(+) and NADH bind to alkaline phosphatase at a common site. Adenosine and nicotinamide also seem to bind at the NAD site and the binding of adenosine is facilitated by nicotinamide, and vice versa. 4. The facilitation may indicate the occurrence of an induced fit for NAD(+) and NADH. Attempts to desensitize alkaline phosphatase to NAD(+) and NADH inhibition by partial denaturation were unsuccessful. 5. The results are discussed in terms of a two-site model in which separate, but interacting, regions exist on the enzyme to accommodate the adenosine and nicotinamide moieties of NAD, and a single-site model in which the adenosine part of the molecule is bound preferentially and this interacts with the nicotinamide fraction. 6. The activity of alkaline phosphatase can be changed fourfold by alteration of the NAD(+)/NADH ratio. This sensitivity to the redox state of the coenzyme could be a means of controlling phosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352911"}
{"pmid": "4352912", "title": "Equilibrium binding of nicotinamide nucleotides to lactate dehydrogenases.", "content": "Equilibrium binding of nicotinamide nucleotides to lactate dehydrogenases. 1. No discontinuities were observed during the continuous titration with NADH of the lactate dehydrogenases of ox muscle, pig heart, pig muscle, rabbit muscle, dogfish muscle or lobster tail muscle. The binding was monitored by either the enhanced fluorescence of bound NADH or the quenched fluorescence of the protein. A single macroscopic dissociation constant, independent of protein concentration, could be used to describe the binding to each enzyme, and there was no need to postulate the involvement of molecular relaxation effects. 2. The affinity for NADH decreases only threefold between pH6 and 8.5. Above pH9 the affinity decreases more rapidly with increasing pH and is consistent with a group of about pK9.5 facilitating binding. Muscle enzymes bind NADH more weakly than does the pig heart enzyme. 3. Increasing temperature and increasing concentrations of ethanol both weaken NADH binding. 4. NADH binding is weakened by increasing ionic strength. NaCl is more effective than similar ionic strengths derived from sodium phosphate or sodium pyrophosphate. 5. Commercial NAD(+) quenches the protein fluorescence of the heart and muscle isoenzymes. Highly purified NAD(+) does not, and its binding was monitored by competition for the NADH-binding sites. A single macroscopic dissociation constant is sufficient to describe NAD(+) binding at the concentrations tested. The dissociation constant is about 0.3mm and is not sensitive to changed ionic strength and to changed pH in the range pH6-8.5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352912"}
{"pmid": "4352913", "title": "Ionic properties of an essential histidine residue in pig heart lactate dehydrogenase.", "content": "Ionic properties of an essential histidine residue in pig heart lactate dehydrogenase. 1. Pig heart lactate dehydrogenase is inhibited by addition of one equivalent of diethyl pyrocarbonate. The inhibition is due to the acylation of a unique histidine residue which is 10-fold more reactive than free histidine. No other amino acid side chains are modified. 2. The carbethoxyhistidine residue slowly decomposes and the enzyme activity reappears. 3. The essential histidine residue is only slightly protected by the presence of NADH but is completely protected when substrate and substrate analogues bind to the enzyme-NADH complex. The protection is interpreted in terms of a model in which substrates can only bind to the enzyme in which the histidine residue is protonated and is thus not available for reaction with the acylating agent. 4. The apparent pK(a) of the histidine residue in the apoenzyme is 6.8+/-0.2. In the enzyme-NADH complex it is 6.7+/-0.2. 5. Acylated enzyme binds NADH with unchanged affinity. The enzyme is inhibited because substrates and substrate analogues cannot bind at the acylated histidine residue in the enzyme-NADH complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352913"}
{"pmid": "4352914", "title": "The use of ternary complexes to study ionizations and isomerizations during catalysis by lactate dehydrogenase.", "content": "The use of ternary complexes to study ionizations and isomerizations during catalysis by lactate dehydrogenase. 1. The binding of oxamate to pig heart and pig muscle isoenzymes of lactate dehydrogenase in the presence of NADH was studied by fluorescence titration. The dissociation constant of oxamate from the heart enzyme complex is 3mum and from the muscle isoenzyme 25mum at pH5. These values quantitatively increase with pH as predicted if oxamate can bind only to the enzyme-NADH complex if a group with pK6.9 is protonated. There are four non-interacting oxamate-binding sites per tetramer. 2. o-Nitrophenylpyruvate is a poor substrate for both isoenzymes but has a reasonable affinity to the heart isoenzyme. Initially, it forms an enzyme-NADH-substrate complex, which can be detected either by protein-fluorescence quenching or by NADH-fluorescence quenching. The pH-dependence of the dissociation constant of nitrophenylpyruvate also shows that this ternary complex can only form if a group with pK6.8 is protonated. Taken with the results of chemical-modification experiments, these results allow the pK of 6.8 to be assigned to a system probably involving the imidazole side chain of histidine-195. Formation of a ternary complex from a binary one at pH8 is predicted to result in a proton being taken up from solution. 3. Isotope-effect studies with NADH and its deuterium analogue show that the rapidly formed ternary complex with o-nitrophenylpyruvate slowly isomerizes to give an active ternary complex, which then rapidly decomposes to NAD(+). The isomerization is pH-independent, and it is suggested that histidine-195 is still protonated in the activated ternary complex, which is present before hydride transfer. 4. All four subunits of the enzyme are kinetically equivalent with respect to the oxidation of bound NADH by o-nitrophenylpyruvate. 5. A partial mechanism for the enzyme is described which emphasizes the isomerizations and ionizations involved in forming the reduced ternary complex at pH6 and 8.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352914"}
{"pmid": "4352915", "title": "A sensitive and accurate gel osmometer.", "content": "A sensitive and accurate gel osmometer. 1. A bilayer strip, cut from a thin layer of cross-linked polyacrylamide gel cast on to cellulose tissue, forms an open circular loop whose ends are close together. Shrinkage of the gel, in response to the osmotic pressure of a non-penetrating solution, causes a proportional separation of the ends of the loop. This is measured with a microscope and micrometer eyepiece. 2. The resulting effective sensitivity is about 30 times that of the Sephadex-bead osmometer (Ogston & Wells, 1970), i.e. of the order of 5Pa, comparable with that of a membrane osmometer. Use of gel up to 70% (w/v) allows the measurement of molecular weights, as low as 1500 in favourable cases, with an accuracy of 1-2%. The useful range of osmotic pressure is up to 5kPa. A single measurement requires 0.5ml of solution. Equilibration is completed in 20-30min. 3. The method is illustrated by measurements on human serum albumin, ovalbumin, cytochrome c, samples of dextrans, polyvinyl alcohol, and polyethylene glycols 6000 and 1000.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352915"}
{"pmid": "4352916", "title": "The characterization of a non-histone protein isolated from histone F1 preparations.", "content": "The characterization of a non-histone protein isolated from histone F1 preparations. A non-histone protein was obtained by extraction of nuclei derived from rat liver or thymus or ascites-hepatoma cells with 5% (w/v) HClO(4). Separation from histone F1 was achieved by chromatography on DEAE-cellulose. The purified component P1 was characterized and the formation of complexes with histone F1 and polylysine was studied.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352916"}
{"pmid": "4352918", "title": "Relationships between in vivo and in vitro inhibition of acetylcholinesterase (AChE) and impairment of neuromuscular transmission in the rat phrenic-nerve diaphragm by a tertiary anticholinesterase and its quaternary analogue.", "content": "Relationships between in vivo and in vitro inhibition of acetylcholinesterase (AChE) and impairment of neuromuscular transmission in the rat phrenic-nerve diaphragm by a tertiary anticholinesterase and its quaternary analogue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352918"}
{"pmid": "4352917", "title": "Effect of steady illumination on the binding of carbon monoxide by carboxymethylated cytochrome c.", "content": "Effect of steady illumination on the binding of carbon monoxide by carboxymethylated cytochrome c. The quantum yield, [unk], is reported for the photodissociation of CO from reduced carboxymethylated cytochrome c. The values of [unk] obtained are low relative to that for myoglobin and are pH-independent, being 0.23 at pH6.1 and 0.27 at pH9.7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352917"}
{"pmid": "4352919", "title": "Glycolytic mechanisms in Ehrlich ascites tumor cells-effects of disulfide derivatives of pyridine.", "content": "Glycolytic mechanisms in Ehrlich ascites tumor cells-effects of disulfide derivatives of pyridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352919"}
{"pmid": "4352920", "title": "Phospholipids and phospholipase D in the true slime mold Physarum polycephalum.", "content": "Phospholipids and phospholipase D in the true slime mold Physarum polycephalum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352920"}
{"pmid": "4352921", "title": "Age differences in the acyl group composition of phosphoglycerides in myelin isolated from the brain of the rhesus monkey.", "content": "Age differences in the acyl group composition of phosphoglycerides in myelin isolated from the brain of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352921"}
{"pmid": "4352922", "title": "The retention of arachidonic acid in ethanolamine plasmalogens of rat testes during essential fatty acid deficiency.", "content": "The retention of arachidonic acid in ethanolamine plasmalogens of rat testes during essential fatty acid deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352922"}
{"pmid": "4352923", "title": "Fatty acid amide of glycerylphosphorylethanolamine-a lytic lipid from hog stomach.", "content": "Fatty acid amide of glycerylphosphorylethanolamine-a lytic lipid from hog stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352923"}
{"pmid": "4352924", "title": "Kinetics of lipoprotein lipase activity: effects of the substrate apoprotein on reaction velocity.", "content": "Kinetics of lipoprotein lipase activity: effects of the substrate apoprotein on reaction velocity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352924"}
{"pmid": "4352925", "title": "Glucose stimulation of fatty acid desaturation in liver of newly-hatched chicks.", "content": "Glucose stimulation of fatty acid desaturation in liver of newly-hatched chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352925"}
{"pmid": "4352926", "title": "Angiography of the primary retroperitoneal tumors.", "content": "Angiography of the primary retroperitoneal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352926"}
{"pmid": "4352927", "title": "Haemonchus contortus: enzymes. 3. Glutamate dehydrogenase.", "content": "Haemonchus contortus: enzymes. 3. Glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352927"}
{"pmid": "4352928", "title": "Studies on metabolism of lung fluke genus Paragonimus. VII. Action of bithionol on glycolytic and oxidative metabolism of adult worms.", "content": "Studies on metabolism of lung fluke genus Paragonimus. VII. Action of bithionol on glycolytic and oxidative metabolism of adult worms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352928"}
{"pmid": "4352929", "title": "Reactivity with oxygen of bacterial cytochrome oxidases a1, aa3 and o.", "content": "Reactivity with oxygen of bacterial cytochrome oxidases a1, aa3 and o.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352929"}
{"pmid": "4352930", "title": "Effect of luteinizing hormone on 3',5'-cyclic AMP and testosterone production in isolated interstitial tissue of rat testis.", "content": "Effect of luteinizing hormone on 3',5'-cyclic AMP and testosterone production in isolated interstitial tissue of rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352930"}
{"pmid": "4352931", "title": "Interaction of transfer RNA with the 30 S subunits of ribosomes in the absence of messenger.", "content": "Interaction of transfer RNA with the 30 S subunits of ribosomes in the absence of messenger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352931"}
{"pmid": "4352932", "title": "Role of split proteins from 30 S subunits in the ribosome-EF-T GTPase reaction.", "content": "Role of split proteins from 30 S subunits in the ribosome-EF-T GTPase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352932"}
{"pmid": "4352933", "title": "Continuous directional degradation. A novel method for sequence analysis of polyribonucleotides.", "content": "Continuous directional degradation. A novel method for sequence analysis of polyribonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352933"}
{"pmid": "4352935", "title": "Routine isolation of the 70 S RNA of a murine oncornavirus by use of an unesterified cellulose column.", "content": "Routine isolation of the 70 S RNA of a murine oncornavirus by use of an unesterified cellulose column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352935"}
{"pmid": "4352937", "title": "Studies on the structure of lipoprotein A of human high density lipoprotein HDL3: the spherically averaged electron density distribution.", "content": "Studies on the structure of lipoprotein A of human high density lipoprotein HDL3: the spherically averaged electron density distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352937"}
{"pmid": "4352936", "title": "Protein phosphokinases of bound and free thyroid polyribosomes.", "content": "Protein phosphokinases of bound and free thyroid polyribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352936"}
{"pmid": "4352934", "title": "The primary structure of oligonucleotides. Partial apurinization as a method to determine the positions of purine and pyrimidine residues.", "content": "The primary structure of oligonucleotides. Partial apurinization as a method to determine the positions of purine and pyrimidine residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352934"}
{"pmid": "4352938", "title": "The management of bleeding intraductal papilloma of the breast.", "content": "The management of bleeding intraductal papilloma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352938"}
{"pmid": "4352939", "title": "Primary malignant tumors of the liver.", "content": "Primary malignant tumors of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352939"}
{"pmid": "4352941", "title": "The effect of adrenalectomy on blood corticotrophin in the rat.", "content": "The effect of adrenalectomy on blood corticotrophin in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352941"}
{"pmid": "4352940", "title": "Corticosteroid release by adrenal tissue from foetal and newborn lambs in response to corticotrophin stimulation in a perifusion system in vitro.", "content": "Corticosteroid release by adrenal tissue from foetal and newborn lambs in response to corticotrophin stimulation in a perifusion system in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352940"}
{"pmid": "4352943", "title": "The effect of pyridine nucleotides and cyclic AMP on the synthesis of progestational steroids in subcellular fractions of rabbit ovarian interstitial tissue.", "content": "The effect of pyridine nucleotides and cyclic AMP on the synthesis of progestational steroids in subcellular fractions of rabbit ovarian interstitial tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352943"}
{"pmid": "4352942", "title": "Adrenocortical function in the Australian brush-tailed possum Trichosurus vulpecula (Kerr).", "content": "Adrenocortical function in the Australian brush-tailed possum Trichosurus vulpecula (Kerr).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352942"}
{"pmid": "4352944", "title": "The relationship between cortisol and adrenocorticotrophin levels in human plasma.", "content": "The relationship between cortisol and adrenocorticotrophin levels in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352944"}
{"pmid": "4352945", "title": "The effect of intravenous catecholamines on circulating levels of growth hormone, corticotrophin and cortisol in man.", "content": "The effect of intravenous catecholamines on circulating levels of growth hormone, corticotrophin and cortisol in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352945"}
{"pmid": "4352947", "title": "Characterization of corticotrophin-like intermediate lobe peptides from rat and pig pituitaries, and identification of alpha-melanocyte-stimulating hormone in the rat pituitary.", "content": "Characterization of corticotrophin-like intermediate lobe peptides from rat and pig pituitaries, and identification of alpha-melanocyte-stimulating hormone in the rat pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352947"}
{"pmid": "4352946", "title": "The effect of increased K+ concentration and serotonin on cyclic AMP and corticosterone output by dispersed adrenal zona glomerulosa cells.", "content": "The effect of increased K+ concentration and serotonin on cyclic AMP and corticosterone output by dispersed adrenal zona glomerulosa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352946"}
{"pmid": "4352949", "title": "Halotolerant collagenolytic activity of Achromobacter iophagus.", "content": "Halotolerant collagenolytic activity of Achromobacter iophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352949"}
{"pmid": "4352948", "title": "Studies on proteolytic activity of mycoplasmas: gelatinolytic property.", "content": "Studies on proteolytic activity of mycoplasmas: gelatinolytic property.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352948"}
{"pmid": "4352950", "title": "Intersensory interactions in Hermissenda.", "content": "Intersensory interactions in Hermissenda. Hair cells of the Hermissenda statocyst respond to photic stimulation. This response requires the presence of at least one of the two eyes. Two principal hair cell responses to light were observed. The activity of photoreceptors in response to a light step is interrupted during firing of contralateral hair cells. The intersensory interactions between the statocyst and visual pathway underlying these responses were examined with simultaneous intracellular recordings. Evidence is presented that the statocyst of Hermissenda is an important channel for visual information.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352950"}
{"pmid": "4352951", "title": "The quantal nature of synaptic transmission at the neuromuscular junction of a spider.", "content": "The quantal nature of synaptic transmission at the neuromuscular junction of a spider. Spontaneous and evoked release of transmitter at neuromuscular junctions in three different leg muscles of a tarantula (Dugesiella hentzi) was investigated. In most cases the spontaneous miniature potentials were released independently, although bursts from single synaptic junctions occasionally occurred. In contrast to recent findings in other arthropod muscles, focal extracellular recording from junctional areas revealed that the evoked release of transmitter quanta followed Poisson's theorem at low quantal content synaptic junctions in arachnid muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352951"}
{"pmid": "4352953", "title": "Ultraviolet irradiation of herpes simplex virus: action spectrum for the survival of infectivity in relation to the small-plaque effect.", "content": "Ultraviolet irradiation of herpes simplex virus: action spectrum for the survival of infectivity in relation to the small-plaque effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352953"}
{"pmid": "4352954", "title": "The polypeptides of three rhinoviruses.", "content": "The polypeptides of three rhinoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352954"}
{"pmid": "4352952", "title": "Evidence for the lack of glycoprotein in the encephalomyocarditis virus particle.", "content": "Evidence for the lack of glycoprotein in the encephalomyocarditis virus particle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352952"}
{"pmid": "4352955", "title": "The subunits of murine sarcoma-leukaemia virus RNA.", "content": "The subunits of murine sarcoma-leukaemia virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352955"}
{"pmid": "4352956", "title": "Interference as a measure of cross-relationships in the vesicular stomatitis group of rhabdo viruses.", "content": "Interference as a measure of cross-relationships in the vesicular stomatitis group of rhabdo viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352956"}
{"pmid": "4352957", "title": "The infectivity of the nucleic acid of aerosol-inactivated poliovirus.", "content": "The infectivity of the nucleic acid of aerosol-inactivated poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352957"}
{"pmid": "4352959", "title": "Herpesvirus hominis type I encephalitis treated with cytarabine, an unresolved problem in encephalitis.", "content": "Herpesvirus hominis type I encephalitis treated with cytarabine, an unresolved problem in encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352959"}
{"pmid": "4352961", "title": "Radical artery occlusion by a carpal ganglion. Case report.", "content": "Radical artery occlusion by a carpal ganglion. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352961"}
{"pmid": "4352962", "title": "Herpes simplex virus as a source of thymidine kinase for thymidine kinase-deficient mouse cells: suppression and reactivation of the viral enzyme.", "content": "Herpes simplex virus as a source of thymidine kinase for thymidine kinase-deficient mouse cells: suppression and reactivation of the viral enzyme. Thymidine kinase (EC 2.7.1.21)-deficient mouse cells were infected with inactivated herpes simplex virus, after which \"transformed\" cells that produce viral thymidine kinase were isolated. Shortly after transformation, the expression of the viral enzyme could be suppressed and reactivated with high efficiency. On continued multiplication in nonselective medium, the proportion of cells producing the viral enzyme decayed exponentially. This decay seemed to represent a change in the expression of the viral gene for thymidine kinase rather than the loss of the gene from the cells, since the viral enzyme could be apparently reactivated in every cell, albeit at a very low frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352962"}
{"pmid": "4352958", "title": "Evaluation of a program of aftercare for patients discharged from the hospital.", "content": "Evaluation of a program of aftercare for patients discharged from the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352958"}
{"pmid": "4352963", "title": "Relationship of replication and transcription of Simian Virus 40 DNA.", "content": "Relationship of replication and transcription of Simian Virus 40 DNA. RNA produced by the Simian Virus 40 (SV40) mutant tsA30 during lytic infection of kidney cells of African green monkeys was examined by RNA-DNA competition-hybridization. This mutant is temperature-sensitive in a function (gene A) that regulates synthesis of viral DNA. No detectable difference between mutant RNA synthesized at the permissive temperature (33 degrees ) and wild-type viral RNA was found. During continuous infection with the mutant at the restrictive temperature (41 degrees ) only early viral RNA was produced. When mutant DNA and late RNA synthesis were initiated at the permissive temperature, a shift to the restrictive temperature rapidly terminated synthesis of viral DNA but not that of late viral RNA. The data indicate that the function of gene A is required before synthesis of late viral RNA and that after initiation, the production of late RNA continues without further expression of gene A or concomittant viral DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352963"}
{"pmid": "4352965", "title": "Interferon: evidence for its glycoprotein nature.", "content": "Interferon: evidence for its glycoprotein nature. In an attempt to understand the structure of rabbit interferon, the possibility of carbohydrate being part of the molecule was tested. Interferon incubated with neuraminidase from Vibrio cholera is homogeneous in charge as revealed by isoelectric focusing. Treatment of \"asialointerferon\" with galactose oxidase (EC 1.1.3.9) from Dactylium dendroides and subsequent reduction with tritiated sodium borohydride yields labeled material with unimpaired antiviral activity. Enzymic incorporation of N-[(14)C]acetylneuraminic acid into tritiated asialointerferon restores the original charge heterogeneity. The newly generated sialointerferon contains both (3)H and (14)C activity. Asialointerferon is retained by an affinity column containing phytohemagglutinin from Phaseolus vulgaris and can be displaced from the adsorbent by a glycoprotein of known structure. It is concluded that rabbit interferon is a glycoprotein containing the terminal oligosaccharide sequence sialic acid --> galactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352965"}
{"pmid": "4352966", "title": "Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in triglyceride-rich lipoproteins.", "content": "Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in triglyceride-rich lipoproteins. Lipoproteins of very low density that are unusually rich in cholesteryl esters accumulate in blood plasma in a characteristic primary form of human hyperlipoproteinemia. These lipoproteins, which are thought to be products of the initial catabolic step in the metabolism of normal triglyceride-rich lipoproteins, have beta rather than pre-beta mobility on electrophoresis, presumably because they have lost certain protein components from their surface. In this study, we have used polyacrylamide gel electrophoresis of apoprotein components that are soluble in tetramethylurea to show that the very low-density lipoprotein fraction of blood serum from seven patients with hyperlipoproteinemia contains unusually large amounts of an arginine-rich protein. Pre-beta migrating, very low-density lipoproteins separated from serum of post-absorptive patients and chylomicrons obtained after a fat-rich meal contain normal amounts of this arginine-rich protein, but beta-migrating, very low-density lipoproteins and chylomicron-like particles separated from serum of post-absorptive patients contain more than twice as much. These apparently partially degraded lipoproteins also contain more tetramethylurea-insoluble protein and smaller amounts of the other soluble protein components than their normal counterparts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352966"}
{"pmid": "4352964", "title": "Collagen and procollagen production by a clonal line of Schwann cells.", "content": "Collagen and procollagen production by a clonal line of Schwann cells. A well-characterized line of rat Schwann cells has been examined for its ability to produce collagen. About 14% of the [(3)H]proline in the proteins that were secreted into the culture medium by the cells was hydroxylated, while only 1% of the labeled proteins in the cell layer contained [(3)H]hydroxyproline. Three sizes of procollagen polypeptides, of molecular weights about 105,000, 120,000, and 155,000, were present in the medium, as well as tropocollagen molecules that contained the usual alpha1 and alpha2 chains. Subsequently, the Schwann cells ceased producing the smaller collagenous polypeptides, although the total [(3)H]hydroxyproline content of the medium was unchanged. The [(3)H]hydroxyproline was almost entirely accounted for by the polypeptide of 155,000 daltons; this peptide was rapidly digested by collagenase or pepsin or chymotrypsin. The destruction by pepsin and chymotrypsin indicates that the large polypeptide, in contrast to procollagen and tropocollagen, is not in the collagenous (helical) conformation. Possibly, this substance is a very early form of procollagen that does not fold into the collagen conformation. The data show that cells of neuroectodermal origin can synthesize collagen, and also suggest that Schwann cells may be responsible for a large proportion of the collagen seen in peripheral neurinomas in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352964"}
{"pmid": "4352967", "title": "A tumor-associated antigen in human nephroblastomas.", "content": "A tumor-associated antigen in human nephroblastomas. Antisera prepared against extracts of human nephroblastomas (Wilms' tumors) allowed the characterization in these extracts, and in a few extracts of tumors of other organs, of a tumor-associated antigen. This antigen is different from all previously described antigens, and was named W antigen (W for Wilms). It does not seem to be a carcinoembryonic antigen, and hence it could be of viral origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352967"}
{"pmid": "4352969", "title": "Virus-specific messenger RNA and nascent polypeptides in polyribosomes of cells replicating murine sarcoma-leukemia viruses.", "content": "Virus-specific messenger RNA and nascent polypeptides in polyribosomes of cells replicating murine sarcoma-leukemia viruses. We present evidence that virus-specific RNA is present in polyribosomes of transformed cells replicating the murine sarcoma-leukemia virus complex and that it serves as messenger RNA for the synthesis of viral-coded proteins. Both virus-specific RNA (detected by hybridization with the [(3)H]DNA product of the viral RNA-directed DNA polymerase) and nascent viral polypeptides (measured by precipitation with antiserum to purified virus) were found in membrane-bound and free polyribosomes. Membrane-bound polyribosomes contained a higher content of both virus-specific RNA and nascent viral polypeptides. From 60 to 70% of viral RNA sequences were released from polyribosomes with EDTA, consistent with a function as messenger RNA. Maximum amounts of both virus-specific RNA and nascent viral polypeptides were found in the polyribosome region sedimenting at about 350 S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352969"}
{"pmid": "4352968", "title": "Independent segregation of loci for activation of biologically distinguishable RNA C-type viruses in mouse cells.", "content": "Independent segregation of loci for activation of biologically distinguishable RNA C-type viruses in mouse cells. Two genetic loci for induction of RNA C-type virus in BALB/c mouse embryo cells segregate independently in backcross embryo cell lines. The viruses at these loci are shown to be biologically distinguishable. The first, described previously, codes for activation of a virus that grows preferentially in NIH Swiss embryo cells. The newly detected locus codes for activation of a virus that grows poorly, if at all, in NIH Swiss or BALB/c cells, but replicates well in a rat cell line. Its serologic properties are different from those of viruses of the two major serologic subgroups of murine leukemia virus. The present findings provide support for the hypothesis that the loci for virus induction in BALB/c cells represent genetic information for C-type viruses and that the endogenous viruses are subject to different cellular genetic controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352968"}
{"pmid": "4352970", "title": "Activation of a covalent enzyme-substrate bond by noncovalent interaction with an effector.", "content": "Activation of a covalent enzyme-substrate bond by noncovalent interaction with an effector. The absorption spectrum of an activesite specific chromophoric acyl enzyme, sturgeon beta-(2-furyl)-acryloyl-glyceraldehyde-3-phosphate dehydrogenase, is reported. This acyl enzyme undergoes all of the catalyzed reactions characteristic of the intermediate of the physiological acyl enzyme, 3-phospho-D-glyceroyl-glyceraldehyde-3-phosphate dehydrogenease. The rates of reactions of both these acyl enzymes depend strongly on the extent of interaction of the acyl enzyme with the oxidized coenzyme, NAD(+), even where the \"redox\" properties of the coenzyme are not required. Likewise, the spectral properties of chromophoric acyl enzyme are affected by the extent of bound NAD. Under the pseudophysiological conditions reported herein, there is a stoichiometric limitation of two furylacryloyl-acyl groups per enzyme molecule containing four covalently-equivalent subunits. The binding of NAD both to the apoenzyme and to the diacyl enzyme is heterogeneous: at low extents of NAD occupancy, NAD binding is stronger. The binding to acyl enzyme can be quantitatively described by an enzyme model involving a tetramer with 2-fold symmetry, and consequently containing equal numbers of two classes of sites. NAD binding to difurylacryloyl-enzyme occurs virtually discretely, first to the two unmodified (tight-binding) sites, followed by looser binding to the two acyl-sites. NAD occupancy at these latter sites transforms the chromophoric acyl spectrum from that characteristic of a model furylacryloyl-thiol ester in H(2)O to a highly perturbed furylacryloyl spectrum characteristic of monomeric native \"active-thiol\" furylacryloyl-enzymes. Likewise the acyl reactivity towards arsenolysis depends on the extent of NAD bound to the loose sites. Elimination of the tight binding of NAD to the difurylacryloyl enzyme tetramer by alkylation of the remaining two free SH groups with iodoacetate has no apparent influence on the NAD-dependent furylacryloyl-spectral perturbation at the \"two equivalent acyl sites,\" even though it eliminates the apparent \"negative cooperativity\" in NAD binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352970"}
{"pmid": "4352971", "title": "Relationship between post-transcriptional adenylation of herpes virus RNA and messenger RNA abundance.", "content": "Relationship between post-transcriptional adenylation of herpes virus RNA and messenger RNA abundance. Analysis of the hybridization kinetics of labeled DNA of herpes simplex virus with unlabeled excess RNA from infected cells showed that viral RNA sequences form two classes differing in molar concentration. The abundant class constituted 93.5-99.3% of total virus-specific RNA and was complementary to 14-16% of the early DNA (2 hr after infection) and to 19-22% of the late DNA (8 hr after infection) in the reproductive cycle of the virus. The early RNA sequences were found to be a subset of the late sequences. The scarce sequences constituted 0.7-6.5% of total virus-specific RNA and were complementary to 28-30% of DNA both early and late in the reproductive cycle. In this study, abundant and scarce sequences were quantitatively separated on the basis of the finding that abundant species are adenylated, i.e., contain post-transcriptionally added poly(A), whereas the scarce RNA is not. Thus, nuclear and polyribosomal adenylated RNA were complementary to 24 and 22%, respectively, of viral DNA and, in abundance competition tests, were found to compete with each other and with abundant RNA from infected cells after 8 hr. The nonadenylated polyribosomal RNA was complementary to 27% of total viral DNA of which 6% was also complementary to adenylated polyribosomal RNA. Hybridization kinetics indicated that each of the fractionated adenylated RNA formed two classes complementary to 6 and 21% of viral DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352971"}
{"pmid": "4352972", "title": "Prophylaxis and immunization in mice by use of virus-free defective T particles to protect against intracerebral infection by vesicular stomatitis virus.", "content": "Prophylaxis and immunization in mice by use of virus-free defective T particles to protect against intracerebral infection by vesicular stomatitis virus. Defective interfering T particles of vesicular stomatitis virus provide remarkable protection against viral disease and death when introduced intracerebrally in large numbers along with an otherwise rapidly fatal low dose of standard infectious virus. This profound prophylactic effect of defective T particles is due to homologous autointerference since it is serotype-specific and interferon is not induced. This protective effect can be demonstrated only with preparations of T particles that have been purified completely free of infectious virions. When pure T particles are injected intracerebrally along with large doses of infectious virus, they convert an otherwise rapidly fatal disease process to a slowly progressing virus infection that generally terminates in death after many days of wasting disease and paralysis. Intracerebral injection of virus-free T particles alone is apparently innocuous to mice and stimulates immunity to massive doses of homologous infectious virus. In vitro, virus-free T particles at extremely high multiplicities depress cellular RNA and protein synthesis and kill BHK21 cells in culture, but do not exhibit such effects at moderately high multiplicities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352972"}
{"pmid": "4352974", "title": "Discrimination between messenger ribonucleic acids by a mammalian translation initiation factor.", "content": "Discrimination between messenger ribonucleic acids by a mammalian translation initiation factor. A factor from rabbit-reticulocyte ribosome, which stimulates by 5-fold initiation of hemoglobin mRNA translation in Krebs ascites cell extracts, was purified to homogeneity. The factor, a protein of about 65,000 molecular weight in sodium dodecyl sulfate, discriminates between various mRNAs: it stimulates translation of alpha globin mRNA and of tobacco mosaic virus RNA, but has only a small effect on beta globin mRNA and no effect at all on Mengo virus RNA translation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352974"}
{"pmid": "4352973", "title": "Chemical synthesis and biochemical properties of peptide fragments of apolipoprotein-alanine.", "content": "Chemical synthesis and biochemical properties of peptide fragments of apolipoprotein-alanine. Apolipoprotein-alanine is an apolipoprotein isolated from very-low-density lipoproteins of human plasma. This protein contains 79 amino acids and binds phosphatidyl choline. Four fragments of this molecule corresponding to sequence positions 41-79 (I), 48-79 (II), 55-79 (III), and 61-79 (IV) have been synthesized by standard solid-phase methods. The resulting peptides were cleaved from the resin and deblocked with liquid HF, then purified by chromatography on Sephadex G-50 and DEAE-cellulose. Each purified peptide eluted as a single, symmetrical peak, exhibited a single band on polyacrylamide gel electrophoresis, and gave an amino-acid analysis in good agreement with the theoretical value. Circular dichroism studies indicated that only fragments I and II became more helical in the presence of phosphatidyl choline and significantly inhibited the reactivation of delipidated beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30), an enzyme that requires phosphatidyl choline for activity. When subjected to ultracentrifugation at density 1.064 g/ml in the presence of phosphatidyl choline, fragments I, II, III, and IV floated to the top of the tube to the extent of 85, 50, 13, and 9%, respectively. These results indicate that residues 55-79 do not contain the minimum determinants required for the binding of phospholipid. However, extension of the peptide's N-terminus by seven residues produces a molecule that does bind phosphatidyl choline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352973"}
{"pmid": "4352975", "title": "Measurements of rates of adenosine 3':5'-cyclic monophosphate synthesis in intact Escherichia coli B.", "content": "Measurements of rates of adenosine 3':5'-cyclic monophosphate synthesis in intact Escherichia coli B. A method for labeling adenosine 3':5'-cyclic monophosphate in vivo from precursor adenosine followed by quantitative analysis of the labeled nucleotide is described. When the labeling period is short and the specific activity of the ATP pool is determined, the rate of incorporation of radioactivity corresponds to a determination of adenylate cyclase activity in vivo. In E. coli B the specific activity of adenylate cyclase in vivo varies under different growth conditions. Under all conditions tested, the adenylate cyclase activity in vivo is great enough to account for the pattern of accumulation of cyclic AMP. This is in contrast to previous adenylate cyclase assays in vitro, where the measured enzyme activities were insufficient to account for the amounts of cyclic AMP accumulated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352975"}
{"pmid": "4352977", "title": "Variation of type-B DNA x-ray fiber diagrams with base composition.", "content": "Variation of type-B DNA x-ray fiber diagrams with base composition. Eight natural DNAs of widely differing base composition have been studied by x-ray diffraction in fibers at high relative humidity. The resulting type B diffraction diagrams showed that all of the DNAs had a 34-A pitch and 3.4-A interbase pair separation. However, the intensity distribution on the inner three layer lines was a strong function of the base content. In diffraction diagrams of very AT-rich DNA, the intensity of the first and third layer line was 2- or 3-times stronger than in the patterns of GC-rich DNA. These high humidity diffraction patterns agree with x-ray scattering from solutions of DNA. The results are interpreted to imply that each AT base pair may have a different cross section than a GC pair. If this is so, it would appreciably alter the currently held ideas concerning DNA recognition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352977"}
{"pmid": "4352976", "title": "Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts by lipoproteins.", "content": "Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts by lipoproteins. The activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (EC 1.1.1.34), the rate-limiting enzyme of hepatic cholesterol biosynthesis, is suppressed in human fibroblasts cultured in the presence of serum. This enzyme activity increases by more than 10-fold after the removal of serum from the medium. The rise in enzyme activity requires de novo protein synthesis and is not accompanied by changes in the activities of several other cellular enzymes. The factor responsible for the suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured fibroblasts is present in the sera of at least four mammalian species, and in human serum it is found in the low-density lipoproteins. Human high-density lipoproteins, very low-density lipoproteins from chicken egg yolk, and the fraction of human serum containing no lipoproteins do not suppress the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352976"}
{"pmid": "4352979", "title": "Electron spin resonance studies of electron irradiated peptides. A single crystal of N-acetylglycine at 77 K.", "content": "Electron spin resonance studies of electron irradiated peptides. A single crystal of N-acetylglycine at 77 K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352979"}
{"pmid": "4352978", "title": "ESR and INDO-MO studies of radicals and radical reactions in irradiated single crystals of 5-nitro-6-methyluracil.", "content": "ESR and INDO-MO studies of radicals and radical reactions in irradiated single crystals of 5-nitro-6-methyluracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352978"}
{"pmid": "4352986", "title": "Microlymphangiography of human gastric musosa for the interpretation of early spread of gastric cancer.", "content": "Microlymphangiography of human gastric musosa for the interpretation of early spread of gastric cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352986"}
{"pmid": "4352985", "title": "Dreams and the social environment.", "content": "Dreams and the social environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352985"}
{"pmid": "4352987", "title": "Lipid metabolism in uremia and the effects of dialysate glucose and oral androgen therapy.", "content": "Lipid metabolism in uremia and the effects of dialysate glucose and oral androgen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352987"}
{"pmid": "4352989", "title": "Considerations of the middle molecular hypothesis. II. Neuropathy in nehprectomized patients.", "content": "Considerations of the middle molecular hypothesis. II. Neuropathy in nehprectomized patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352989"}
{"pmid": "4352988", "title": "An approach to \"middle molecules\" identification in artificial kidney dialysate, with reference to neuropathy prevention.", "content": "An approach to \"middle molecules\" identification in artificial kidney dialysate, with reference to neuropathy prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352988"}
{"pmid": "4352990", "title": "Nerve excitability in chronic renal disease.", "content": "Nerve excitability in chronic renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352990"}
{"pmid": "4352991", "title": "Role of pyrophosphate in renal osteodystrophy.", "content": "Role of pyrophosphate in renal osteodystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352991"}
{"pmid": "4352992", "title": "Viraemia and antibody development in chicks following the administration of turkey herpesvirus.", "content": "Viraemia and antibody development in chicks following the administration of turkey herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352992"}
{"pmid": "4352996", "title": "Development of a pharmacy care plan.", "content": "Development of a pharmacy care plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352996"}
{"pmid": "4352997", "title": "Adenovirus in the sinuses of an asthmatic patient with apparent selective antibody deficiencies.", "content": "Adenovirus in the sinuses of an asthmatic patient with apparent selective antibody deficiencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352997"}
{"pmid": "4352998", "title": "Acute ulcerative colitis associated with cytomegalic inclusion virus.", "content": "Acute ulcerative colitis associated with cytomegalic inclusion virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352998"}
{"pmid": "4352999", "title": "Bone collagen metabolism in vitamin D deficiency.", "content": "Bone collagen metabolism in vitamin D deficiency. Radioisotope studies have shown that collagen synthesized in the shafts of bones from rachitic rats and chicks is similar in chain composition to that normally synthesized. However, the extent of lysine hydroxylation in both alpha1- and alpha2-chains is increased, by approx. 15-30% in the rat and by 50% in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4352999"}
{"pmid": "4353000", "title": "Hepatic redox state and gluconeogenesis from lactate in vivo in the rat.", "content": "Hepatic redox state and gluconeogenesis from lactate in vivo in the rat. 1. To examine the role of the hepatic redox state on the rate of gluconeogenesis the effects of sodium crotonate injection (6mmol/kg body wt.) on rat liver metabolite concentrations and gluconeogenesis from lactate were studied in vivo. 2. Crotonate caused a marked oxidation of cytoplasmic and mitochondrial redox couples; decreases were observed in the ratios of [lactate]/[pyruvate], [glycerol 3-phosphate]/[dihydroxyacetone phosphate], [hydroxybutyrate]/[acetoacetate] and measured [NAD(+)]/[NADH]. 3. Increases occurred in the liver concentrations of all gluconeogenic intermediates from pyruvate through to glucose 6-phosphate, but there was no change in lactate concentration. 4. To determine whether gluconeogenesis from lactate was altered by the more-oxidized hepatic redox state l-[2-(14)C]lactic acid was infused into the inferior vena cava (50mumol/min per kg body wt.) and the incorporation of radioactivity into blood glucose was measured. 5. Administration of crotonate transiently decreased the rate of lactate incorporation into glucose but within a few minutes the rate of incorporation returned to that of the controls. 6. The results indicate that in these experiments alteration of the NAD(+)-NADH systems of cytoplasm and mitochondria to a more-oxidized state did not change the rate of gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353000"}
{"pmid": "4353002", "title": "The absence of an integrated copy of mitochondrial DNA in the nuclear genome of Tetrahymena pyriformis.", "content": "The absence of an integrated copy of mitochondrial DNA in the nuclear genome of Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353002"}
{"pmid": "4353001", "title": "The effect of glucose, insulin and noradrenaline on lipolysis, and on the concentrations of adenosine 3':5'-cyclic monophosphate and adenosine 5'-triphosphate in adipose tissue.", "content": "The effect of glucose, insulin and noradrenaline on lipolysis, and on the concentrations of adenosine 3':5'-cyclic monophosphate and adenosine 5'-triphosphate in adipose tissue. Glycerol release and tissue concentrations of ATP and cyclic AMP were followed during the incubation of adipose tissue with or without glucose, insulin and noradrenaline. Glucose plus insulin or, to a lesser extent, glucose alone increased the accumulation of glycerol during incubations both with and without noradrenaline by slowing the decline in the rate of glycerol release with time. Insulin alone decreased the accumulation by accelerating the fall in glycerol release. In the absence of noradrenaline, ATP and cyclic AMP concentrations were not significantly affected by insulin or glucose. With noradrenaline or noradrenaline plus insulin the ATP concentration gradually fell. With noradrenaline plus glucose the ATP concentration fell rapidly and then stabilized, or, if insulin was also present, returned to the control value. In the presence of noradrenaline, the concentration of cyclic AMP rose during the first 20min and then fell. Insulin lowered the peak concentration of cyclic AMP, but glucose had no effect either on the peak value or the fall in the concentration of the nucleotide. The increase and fall in the concentration of cyclic AMP with noradrenaline or noradrenaline plus insulin bore similarities to the increase and decline in the lipolytic rate in incubations without glucose. It is proposed that glucose stimulates ATP production by furnishing glycerol 1-phosphate and thus removing free fatty acids, but that it can influence lipolysis by a mechanism which is distinct from any which is mediated by free fatty acids, possibly by inhibiting the inactivation of the lipase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353001"}
{"pmid": "4353003", "title": "The analysis of polydeoxyribonucleotides by digestion with phosphatase and phosphodiesterases.", "content": "The analysis of polydeoxyribonucleotides by digestion with phosphatase and phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353003"}
{"pmid": "4353004", "title": "Ribosomal RNA cistron topography in Escherichia coli.", "content": "Ribosomal RNA cistron topography in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353004"}
{"pmid": "4353012", "title": "A clinicopathologic analysis of adriamycin cardiotoxicity.", "content": "A clinicopathologic analysis of adriamycin cardiotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353012"}
{"pmid": "4353013", "title": "Radiologic evaluation of soft tissue tumors. A retrospective study.", "content": "Radiologic evaluation of soft tissue tumors. A retrospective study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353013"}
{"pmid": "4353014", "title": "Perineural invasion and anaplastic transformation of verrucous carcinoma.", "content": "Perineural invasion and anaplastic transformation of verrucous carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353014"}
{"pmid": "4353016", "title": "Cirrhosis and hepatoma occurring at Boston City Hospital (1917-1968).", "content": "Cirrhosis and hepatoma occurring at Boston City Hospital (1917-1968).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353016"}
{"pmid": "4353015", "title": "Sinus histiocytosis with massive lymphadenopathy. Report of a case associated with elevated EBV antibody titers.", "content": "Sinus histiocytosis with massive lymphadenopathy. Report of a case associated with elevated EBV antibody titers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353015"}
{"pmid": "4353017", "title": "Benign liver cell tumors. Classification and ultrastructural pathology.", "content": "Benign liver cell tumors. Classification and ultrastructural pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353017"}
{"pmid": "4353018", "title": "Malignant mixed tumor of the gallbladder.", "content": "Malignant mixed tumor of the gallbladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353018"}
{"pmid": "4353020", "title": "Benign lipoblastomatosis. An analysis of 35 cases.", "content": "Benign lipoblastomatosis. An analysis of 35 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353020"}
{"pmid": "4353019", "title": "Pituitary insufficiency, inappropriate antidiuretic hormone (ADH) secretion, and carcinoma of the bronchus.", "content": "Pituitary insufficiency, inappropriate antidiuretic hormone (ADH) secretion, and carcinoma of the bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353019"}
{"pmid": "4353021", "title": "Studies on the relationship between the catecholamine distribution in the atrium and the specific granules present in atrial muscle cells. 1. Isolation of a purified specific granule subfraction.", "content": "Studies on the relationship between the catecholamine distribution in the atrium and the specific granules present in atrial muscle cells. 1. Isolation of a purified specific granule subfraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353021"}
{"pmid": "4353022", "title": "Techniques for studying adrenergic transmitter release in an isolated perfused artery.", "content": "Techniques for studying adrenergic transmitter release in an isolated perfused artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353022"}
{"pmid": "4353023", "title": "New approaches to treatment of osteogenesis imperfecta.", "content": "New approaches to treatment of osteogenesis imperfecta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353023"}
{"pmid": "4353025", "title": "Thermal activation of the cyclic AMP stimulated sodium transport across isolated toad bladder and Na+-K+ ATPase in toad bladder homogenates.", "content": "Thermal activation of the cyclic AMP stimulated sodium transport across isolated toad bladder and Na+-K+ ATPase in toad bladder homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353025"}
{"pmid": "4353026", "title": "Synaptic frequency demodulation.", "content": "Synaptic frequency demodulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353026"}
{"pmid": "4353028", "title": "Sleep in parabiosis.", "content": "Sleep in parabiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353028"}
{"pmid": "4353027", "title": "Crayfish neuromuscular junction: facilitation with constant nerve terminal potential.", "content": "Crayfish neuromuscular junction: facilitation with constant nerve terminal potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353027"}
{"pmid": "4353029", "title": "Sleep in the giant South American armadillo Priodontes giganteus (Edentata, Mammalia).", "content": "Sleep in the giant South American armadillo Priodontes giganteus (Edentata, Mammalia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353029"}
{"pmid": "4353031", "title": "Vesicle hypothesis: effect of nerve stimulation on the synaptic vesicles of motor endplates.", "content": "Vesicle hypothesis: effect of nerve stimulation on the synaptic vesicles of motor endplates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353031"}
{"pmid": "4353030", "title": "Induction of ingestive responses by cAMP applied into the rat hypothalamus.", "content": "Induction of ingestive responses by cAMP applied into the rat hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353030"}
{"pmid": "4353032", "title": "The influence of some biogenic amines and cyclic N-2-O-dibutyryl-adenosine-3',5'-monophosphate on glycogen content in rat brain slices.", "content": "The influence of some biogenic amines and cyclic N-2-O-dibutyryl-adenosine-3',5'-monophosphate on glycogen content in rat brain slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353032"}
{"pmid": "4353034", "title": "Milk microsomes, viruses, and the milk fat globule membrane.", "content": "Milk microsomes, viruses, and the milk fat globule membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353034"}
{"pmid": "4353033", "title": "The influence of propranolol and dibenzyline on glycogenolytic effects of some biogenic amines in rat brain slices.", "content": "The influence of propranolol and dibenzyline on glycogenolytic effects of some biogenic amines in rat brain slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353033"}
{"pmid": "4353035", "title": "Pea phytohemagglutinin selective agglutination of tumour cells.", "content": "Pea phytohemagglutinin selective agglutination of tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353035"}
{"pmid": "4353036", "title": "Radioimmunological determination of plasma cortisol.", "content": "Radioimmunological determination of plasma cortisol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353036"}
{"pmid": "4353037", "title": "Behaviour of a guanidine-dependent strain of poliovirus 1 in sucrose density and pH gradients.", "content": "Behaviour of a guanidine-dependent strain of poliovirus 1 in sucrose density and pH gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353037"}
{"pmid": "4353038", "title": "Thiopyrimidines: specific inhibitors of poliovirus induced early cell damages.", "content": "Thiopyrimidines: specific inhibitors of poliovirus induced early cell damages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353038"}
{"pmid": "4353039", "title": "Gas-liquid and thin-layer chromatography of some 3- and 3,x-substituted pyrenes.", "content": "Gas-liquid and thin-layer chromatography of some 3- and 3,x-substituted pyrenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353039"}
{"pmid": "4353040", "title": "Circular thin-layer chromatography for diagnosis and follow-up of neural crest tumours.", "content": "Circular thin-layer chromatography for diagnosis and follow-up of neural crest tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353040"}
{"pmid": "4353041", "title": "Layer pre-loading in partition thin-layer chromatography of amino acids.", "content": "Layer pre-loading in partition thin-layer chromatography of amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353041"}
{"pmid": "4353042", "title": "Generation of ATP during cytochrome-linked anaerobic electron transport in propionic acid bacteria.", "content": "Generation of ATP during cytochrome-linked anaerobic electron transport in propionic acid bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353042"}
{"pmid": "4353043", "title": "Acquisition of parainfluenza 3 virus infection by hospitalized children. I. Frequencies, rates, and temporal data.", "content": "Acquisition of parainfluenza 3 virus infection by hospitalized children. I. Frequencies, rates, and temporal data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353043"}
{"pmid": "4353044", "title": "Viral interference with exoerythrocytic forms of malaria (Plasmodium gallinaceum) in ovo.", "content": "Viral interference with exoerythrocytic forms of malaria (Plasmodium gallinaceum) in ovo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353044"}
{"pmid": "4353046", "title": "An outbreak of a febrile disease (Izumi fever) associated with high anti-eb virus antibody titers.", "content": "An outbreak of a febrile disease (Izumi fever) associated with high anti-eb virus antibody titers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353046"}
{"pmid": "4353045", "title": "Interference mediated by a variant of Sindbis virus. II. Actinomycin D-sensitive interference in the absence of interferon.", "content": "Interference mediated by a variant of Sindbis virus. II. Actinomycin D-sensitive interference in the absence of interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353045"}
{"pmid": "4353047", "title": "The establishment of cultured cell lines from the patients with Izumi fever and infectious mononucleosis like diseases.", "content": "The establishment of cultured cell lines from the patients with Izumi fever and infectious mononucleosis like diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353047"}
{"pmid": "4353048", "title": "Some biochemical studies on the nonspecific acid phosphomonoesterases of Dirofilaria immitis.", "content": "Some biochemical studies on the nonspecific acid phosphomonoesterases of Dirofilaria immitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353048"}
{"pmid": "4353050", "title": "Alterations in lipoprotein pattern in liver plasma membranes from rats of different ages.", "content": "Alterations in lipoprotein pattern in liver plasma membranes from rats of different ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353050"}
{"pmid": "4353049", "title": "Basic mechanisms of aging in the neuromuscular system.", "content": "Basic mechanisms of aging in the neuromuscular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353049"}
{"pmid": "4353052", "title": "Biosynthesis of collagen (14C)hydroxyproline and (14C)hydroxylysine during maturation of chick embryos.", "content": "Biosynthesis of collagen (14C)hydroxyproline and (14C)hydroxylysine during maturation of chick embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353052"}
{"pmid": "4353051", "title": "Some properties of seryl-tRNA synthetase from rat liver.", "content": "Some properties of seryl-tRNA synthetase from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353051"}
{"pmid": "4353053", "title": "Rearing experience, stress and adrenocorticosteroids in the rhesus monkey.", "content": "Rearing experience, stress and adrenocorticosteroids in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353053"}
{"pmid": "4353054", "title": "Influence of environmental temperature on the sleep-wakefulness cycle in the rat.", "content": "Influence of environmental temperature on the sleep-wakefulness cycle in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353054"}
{"pmid": "4353064", "title": "Does the desert black snake venom inhibit release of acetylcholine from motor nerve endings?", "content": "Does the desert black snake venom inhibit release of acetylcholine from motor nerve endings?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353064"}
{"pmid": "4353069", "title": "The mechanisms of testosterone action of the sebaceous glands of the Syrian hamster.", "content": "The mechanisms of testosterone action of the sebaceous glands of the Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353069"}
{"pmid": "4353071", "title": "Complications of antimicrobial therapy.", "content": "Complications of antimicrobial therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353071"}
{"pmid": "4353070", "title": "Three sites for hormonal control of the pigment cell.", "content": "Three sites for hormonal control of the pigment cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353070"}
{"pmid": "4353072", "title": "Microbiologic studies on young infants with lower respiratory tract disease.", "content": "Microbiologic studies on young infants with lower respiratory tract disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353072"}
{"pmid": "4353073", "title": "Amebic liver abscess in childhood. A case study of a 21-month-old Thai child and a literature review.", "content": "Amebic liver abscess in childhood. A case study of a 21-month-old Thai child and a literature review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353073"}
{"pmid": "4353067", "title": "Cytologic detection of minute ovarian, endometrial and breast carcinomas, with emphasis on clinical-pathological approaches.", "content": "Cytologic detection of minute ovarian, endometrial and breast carcinomas, with emphasis on clinical-pathological approaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353067"}
{"pmid": "4353074", "title": "Pneumonia and massive pleural effusion associated with adenovirus type 7.", "content": "Pneumonia and massive pleural effusion associated with adenovirus type 7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353074"}
{"pmid": "4353075", "title": "False positive roentgenologic diagnosis of small intracanalicular acoustic neurinomas.", "content": "False positive roentgenologic diagnosis of small intracanalicular acoustic neurinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353075"}
{"pmid": "4353076", "title": "Radiation therapy of the glomus jugulare tumor.", "content": "Radiation therapy of the glomus jugulare tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353076"}
{"pmid": "4353068", "title": "Cytologic diagnosis of salivary gland tumors by aspiration biopsy.", "content": "Cytologic diagnosis of salivary gland tumors by aspiration biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353068"}
{"pmid": "4353079", "title": "An 18-month longitudinal lymphographic study of filarial diseases in dogs infected with Brugia pahangi (Buckley and Edeson, 1956).", "content": "An 18-month longitudinal lymphographic study of filarial diseases in dogs infected with Brugia pahangi (Buckley and Edeson, 1956).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353079"}
{"pmid": "4353080", "title": "A study of some enzymes of glycerolipid biosynthesis in rat liver after subtotal hepatectomy.", "content": "A study of some enzymes of glycerolipid biosynthesis in rat liver after subtotal hepatectomy. 1. The accumulation of triglyceride in the liver remnant after subtotal hepatectomy (removal of 82% of the liver) exceeded that described for partial hepatectomy (removal of 70% of the liver). 2. Palmitoyl-CoA synthetase, glycerol phosphate acyltransferase and diglyceride acyltransferase activities were measured in the microsomal fraction, and phosphatidate phosphohydrolase activity was measured in the particle-free supernatant fraction, prepared from the liver remnant at various times after subtotal hepatectomy. 3. The only enzyme showing a significant change in specific activity was phosphatidate phosphohydrolase. The specific activity was approximately fivefold that of the control value at 6h after operation and threefold that of the control at 10, 16 and 24h after operation. A smaller increase in the specific activity of the enzyme in sham-operated animals occurred only at 6h after operation. 4. However, at this time the total phosphohydrolase activity of the remaining liver in the sham-operated rats was approximately threefold that in hepatectomized rats. 5. Injection of actinomycin D prevented the increase in activity of phosphatidate phosphohydrolase but did not prevent the accumulation of triglyceride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353080"}
{"pmid": "4353081", "title": "The use of deoxyribonucleic acid-cellulose chromatography and isoelectric focusing for the characterization and partial purification of steroid-receptor complexes.", "content": "The use of deoxyribonucleic acid-cellulose chromatography and isoelectric focusing for the characterization and partial purification of steroid-receptor complexes. 1. Two characteristic properties of the specific high-affinity steroid-binding proteins or receptors, their ability to bind to DNA-cellulose and their relatively acidic isoelectric point, have been exploited as a means of purification. These two fundamental properties distinguish the receptors from the steroid-binding proteins in serum and the non-specific low-affinity steroid-binding proteins in hormone-responsive cells. 2. A significant degree of purification of both cytoplasmic and nuclear steroid-receptor complexes can be achieved with practical facility by these procedures. The purity of the receptor complexes is sufficient to enable studies on their possible control of metabolic processes to be investigated in the future. 3. After extensive purification the physicochemical properties of the cytoplasmic androgen-receptor complex, such as sedimentation coefficient, were unchanged. Further, the purified complex fully retained at least one of its fundamental physiological properties, namely the ability to transfer 5alpha-dihydrotestosterone (17beta-hydroxy-5alpha-androstan-3-one) into chromatin in vitro. 4. The methods may also be employed for studying the changes in the structure and properties of the receptor complexes that are an essential prerequisite for the transfer of cytoplasmic receptor complexes into nuclear chromatin. The temperature-dependence of the binding of androgen-receptor complexes into chromatin is essentially due to a major change in cytoplasmic receptor complex before its attachment to nuclear chromatin. 5. The resolution of these analytical procedures was sufficient to enable a critical comparison of the receptor proteins from different male accessory glands to be undertaken. From these studies, no substantial evidence in support of the tissue specificity of androgen receptors could be established; rather the receptors from different androgen-dependent glands were remarkably similar in physicochemical properties. 6. Although the methods were initially developed for the partial purification of androgen-receptor complexes, they are equally suitable for the prompt and extensive purification of oestrogen-receptor and progesterone-receptor complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353081"}
{"pmid": "4353085", "title": "Adenosine 3':5'-cyclic monophosphate concentrations and phosphodiesterase activities during axenic growth and differentiation of cells of the cellular slime mould Dictyostelium discoideum.", "content": "Adenosine 3':5'-cyclic monophosphate concentrations and phosphodiesterase activities during axenic growth and differentiation of cells of the cellular slime mould Dictyostelium discoideum. During growth of myxamoebae of Dictyostelium discoideum (strain Ax-2) in axenic medium, the myxamoebae secrete cyclic AMP. As the cells leave the exponential phase of growth and enter the stationary phase, there is an approximate doubling of the intracellular cyclic AMP content, but the amount of extracellular cyclic AMP remains proportional, at all times, to the number of myxamoebae present. During development of axenically grown myxamoebae, there is first a rise in the intracellular concentration of cyclic AMP, followed by a rise in the amount of extracellular cyclic AMP, which reaches a peak at the time of aggregation and then declines. There is a second peak in the amount of extracellular cyclic AMP found at the time of fruiting-body formation, but this second peak is not associated with a rise in the intracellular cyclic AMP concentration. Controls thus exist over the synthesis and secretion of cyclic AMP. Evidence is presented for the belief that the activity of the adenylate cyclase enzyme controls the amount of cyclic AMP synthesized rather than the activity or amount of cyclic AMP phosphodiesterase present. Similar changes occur in extracellular cyclic AMP and phosphodiesterase concentrations during incubation of myxamoebae in buffered suspensions to those occuring during the first few hours of development of such cells on solid media, but the timing of these changes is different.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353085"}
{"pmid": "4353084", "title": "Regulation of renal gluconeogenesis by calcium ions, hormones and adenosine 3':5'-cyclic monophosphate.", "content": "Regulation of renal gluconeogenesis by calcium ions, hormones and adenosine 3':5'-cyclic monophosphate. 1. The effect of Ca(2+), glucagon, adrenaline and adenosine 3':5'-cyclic monophosphate on gluconeogenesis by rat kidney-cortex slices was studied. 2. Glucose formation from a range of substrates, with the exception of glycerol, was increased by an increase in extracellular Ca(2+) concentration. 3. Hormones and adenosine 3':5'-cyclic monophosphate, at low Ca(2+) concentrations, stimulated glucose production from several substrates, but not from glycerol, fructose, malate or fumarate. 4. Hormonal stimulation was not detected in the absence of Ca(2+) or at 2.5mm-Ca(2+). 5. Ca(2+), hormones and adenosine 3':5'-cyclic monophosphate had no effect on phosphoenolpyruvate carboxylase activity. 6. It is proposed that Ca(2+) and adenosine 3':5'-cyclic monophosphate-mediated hormone action activate the same rate-limiting step in gluconeogenesis: this step is tentatively identified as the rate of transfer of substrates across the mitochondrial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353084"}
{"pmid": "4353082", "title": "A reappraisal of the effects of adenosine 3':5'-cyclic monophosphate on the function and morphology of the rat prostate gland.", "content": "A reappraisal of the effects of adenosine 3':5'-cyclic monophosphate on the function and morphology of the rat prostate gland. 1. A comparison was made of the binding of 5alpha-dihydrotestosterone (17beta-hydroxy-5alpha-androstan-3-one) and cyclic AMP in the rat prostate gland. Distinct binding mechanisms exist for these compounds, and cyclic AMP cannot serve as a competitor for the 5alpha-dihydrotestosterone-binding sites and vice versa. In contrast with the results obtained with 5alpha-dihydrotestosterone, very small amounts of cyclic AMP are retained in nuclear chromatin and the overall binding of this cyclic nucleotide is not markedly affected by castration. 2. Androgenic stimulation does not lead to major increases in the adenylate cyclase activities associated with any subcellular fraction of the prostate gland. Accordingly, changes in the concentration of cyclic AMP in the prostate gland after hormonal treatment are likely to be small, but these were not measured directly. 3. When administered to whole animals in vivo, small amounts of non-degraded cyclic AMP are found in the prostate gland but sufficient to promote an activation of certain carbohydrate-metabolizing enzymes in the cell supernatant fraction. The stimulatory effects of cyclic AMP were not evident with cytoplasmic enzymes engaged in polyamine synthesis or nuclear RNA polymerases. These latter enzymes were stimulated solely by the administration of testosterone. 4. By making use of antiandrogens, a distinction can be drawn between the biochemical responses attributable to the binding of 5alpha-dihydrotestosterone but not of cyclic AMP. Evidence is presented to suggest that the stimulation of RNA polymerase, ornithine decarboxylase and S-adenosyl-l-methionine decarboxylase is a consequence of the selective binding of 5alpha-dihydrotestosterone. Only the stimulation of glucose 6-phosphate dehydrogenase can be attributed to cyclic AMP or other metabolites of testosterone. 5. Overall, this study indicates that the formation of cyclic AMP is not a major feature of the androgenic response and affects only a restricted number of biochemical processes. Certainly, cyclic AMP cannot be considered as interchangeable with testosterone and its metabolites in the control of the function of the prostate gland. This difference is additionally emphasized by the failure of cyclic AMP to restore the morphology of the prostate gland in castrated animals; morphological restoration only follows the administration of androgens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353082"}
{"pmid": "4353083", "title": "Induction and suppression of the key enzymes of glycolysis and gluconeogenesis in isolated perfused rat liver in response to glucose, fructose and lactate.", "content": "Induction and suppression of the key enzymes of glycolysis and gluconeogenesis in isolated perfused rat liver in response to glucose, fructose and lactate. 1. Measurements were made of the activities of the four key enzymes involved in gluconeogenesis, pyruvate carboxylase (EC 6.4.1.1), phosphoenolpyruvate carboxylase (EC 4.1.1.32), fructose 1,6-diphosphatase (EC 3.1.3.11) and glucose 6-phosphatase (EC 3.1.3.9), of serine dehydratase (EC 4.2.1.13) and of the four enzymes unique to glycolysis, glucokinase (EC 2.7.1.2), hexokinase (EC 2.7.1.1), phosphofructokinase (EC 2.7.1.11) and pyruvate kinase (EC 2.7.1.40), in livers from starved rats perfused with glucose, fructose or lactate. Changes in perfusate concentrations of glucose, fructose, lactate, pyruvate, urea and amino acid were monitored for each perfusion. 2. Addition of 15mm-glucose at the start of perfusion decreased the activity of pyruvate carboxylase. Constant infusion of glucose to maintain the concentration also decreased the activities of phosphoenolpyruvate carboxylase, fructose 1,6-diphosphatase and serine dehydratase. Addition of 2.2mm-glucose initially to give a perfusate sugar concentration similar to the blood sugar concentration of starved animals had no effect on the activities of the enzymes compared with zero-time controls. 3. Addition of 15mm-fructose initially decreased glucokinase activity. Constant infusion of fructose decreased activities of glucokinase, phosphofructokinase, pyruvate carboxylase, phosphoenolpyruvate carboxylase, glucose 6-phosphatase and serine dehydratase. 4. Addition of 7mm-lactate initially elevated the activity of pyruvate carboxylase, as also did constant infusion; maintenance of a perfusate lactate concentration of 18mm induced both pyruvate carboxylase and phosphoenolpyruvate carboxylase activities. 5. Addition of cycloheximide had no effect on the activities of the enzymes after 4h of perfusion at either low or high concentrations of glucose or at high lactate concentration. Cycloheximide also prevented the loss or induction of pyruvate carboxylase and phosphoenolpyruvate carboxylase activities with high substrate concentrations. 6. Significant amounts of glycogen were deposited in all perfusions, except for those containing cycloheximide at the lowest glucose concentration. Lipid was found to increase only in the experiments with high fructose concentrations. 7. Perfusion with either fructose or glucose decreased the rates of ureogenesis; addition of cycloheximide increased urea efflux from the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353083"}
{"pmid": "4353086", "title": "The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity.", "content": "The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity. 1. Protein kinase activity was measured in islets of Langerhans that had been incubated in the presence of agents known to affect insulin release. 2. Glucagon, theophylline, caffeine and 3-isobutyl-1-methylxanthine, agents that raise cyclic AMP concentrations in islet cells and stimulate insulin release, increased protein kinase activity. Adrenaline and diazoxide, agents that decrease cyclic AMP concentrations and inhibit insulin secretion, decreased the activity. 3. The increase in protein kinase activity produced by different concentrations of 3-isobutyl-1-methylxanthine was apparently related to the increase in intracellular concentrations of cyclic AMP. 4. The sulphonylureas, tolbutamide and glibenclamide, agents that increase insulin release, also increased the protein kinase activity; however, leucine, arginine and xylitol, which also stimulate insulin release, were without effect on the kinase activity. 5. Increasing the glucose concentration of the incubation medium from 2 to 20mm had no effect on protein kinase activity. Further, the ability of 3-isobutyl-1-methylxanthine to increase the protein kinase activity was not affected by the glucose concentration of the incubation medium. 6. These results suggest that agents which affect insulin secretion by altering cyclic AMP concentrations may exert their effects on hormone release by altering the activity of a cyclic AMP-dependent protein kinase in islet cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353086"}
{"pmid": "4353087", "title": "Comparative studies on the carbohydrate-containing membrane components of normal and adenosine 3':5'-cyclic monophosphate-treated Chinese hamster ovary cells.", "content": "Comparative studies on the carbohydrate-containing membrane components of normal and adenosine 3':5'-cyclic monophosphate-treated Chinese hamster ovary cells. 1. We investigated some of the changes in plasma-membrane composition that accompany the alteration in cell growth and morphology induced by treating Chinese-hamster ovary cells with dibutyryladenosine 3':5'-cyclic monophosphate (dibutyryl cyclic AMP). 2. A double-labelling technique was employed in which normal cells were given (14)C-labelled precursor, and those treated with dibutyryl cyclic AMP were given (3)H label. l-Leucine, d-glucosamine, and l-fucose were used to label the membranes. 3. After 3 days growth, the two populations of cells were harvested by trypsin treatment, the cells were pooled, and plasma membranes isolated. Proteins and glycoproteins of the membranes were separated by electrophoresis on sodium dodecyl sulphate-polyacrylamide gels, and the radioactive profiles for (14)C and (3)H and the staining patterns with Amido Black were compared. 4. Although certain components of the membrane from treated cells showed marked quantitative changes, there was neither major addition nor major deletions of components. 5. Complete proteolysis of the mixed membranes, of the material released from the cell surface by trypsin, and of the glycoproteins released from the cells into the medium, gave a series of radioactive glycopeptides when either fucose or glucosamine was employed as precursor. 6. After such glycopeptides were fractionated on columns of Sephadex G-50, marked differences in the elution profiles of (3)H and (14)C were noted. Dibutyryl cyclic AMP evidently causes alterations in the overall composition of the carbohydrate components of the cell surface. It was not possible to decide whether this was solely the result of the same glycoproteins being formed but in different proportions, or the result of modifications of oligosaccharide side chains on some of the glycoproteins. 7. Some of the changes were not unlike the reverse of those that accompany the transformation of fibroblasts by oncogenic viruses, and our results lend credence to the idea that the lowered amount of cyclic AMP noted in transformed cells is responsible for their altered surface properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353087"}
{"pmid": "4353090", "title": "Studies on the biosynthesis of cytochrome c.", "content": "Studies on the biosynthesis of cytochrome c. A soluble cytochrome was isolated and purified from the slime mould Physarum polycephalum and identified as cytochrome c by room-temperature and low-temperature (77 degrees K) difference spectroscopy. A close similarity between P. polycephalum and mammalian cytochromes c was suggested by a comparison of the initial rates of oxidation of both proteins by mammalian mitochondria. This similarity was further emphasized by redox titrations and gel-electrophoretic studies which indicated that P. polycephalum cytochrome c has an oxidation-reduction midpoint potential of +257mV at pH7.0 and a molecular weight of 12500+/-1500 (mean+/-maximum deviation for a set of six measurements). P. polycephalum exhibits an absolute requirement for protohaemin for growth. The (59)Fe-labelled haemin was prepared by chemical synthesis from protoporphyrin. The purified product had a specific radioactivity of 0.8+/-0.02muCi/mol. Growth of P. polycephalum in the presence of [(59)Fe]haemin resulted in the incorporation of (59)Fe into the plasmodial cytochrome c. The specific radioactivity of the cytochrome c haem was 0.36+/-0.02muCi/mol. The high specific radioactivity of the cytochrome haem indicates that synthesis of the holoenzyme must proceed by direct attachment of haem to the apoprotein rather than by the intermediate formation of a protoporphyrinogen-apoprotein complex. The observed decrease in the specific radioactivity of the haem group is attributed to exchange of the (59)Fe with unlabelled iron in the plasmodia either before or during attachment of the haem group to the apoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353090"}
{"pmid": "4353089", "title": "Heterogeneous distribution of glucose 6-phosphatase in rat liver microsomal fractions as shown by adaptation of a cytochemical technique.", "content": "Heterogeneous distribution of glucose 6-phosphatase in rat liver microsomal fractions as shown by adaptation of a cytochemical technique. 1. A novel technique for the subfractionation of rat liver smooth and rough microsomal fractions according to their content of glucose 6-phosphatase is described. This technique, based on the Gomori lead histochemical procedure, involves incubation of smooth and rough microsomal fractions with low concentrations of Pb(NO(3))(2) and glucose 6-phosphate. Control experiments, in which enzyme was assayed in the presence of various amounts of Pb(NO(3))(2) or in which microsomal fractions were reisolated after incubation with low concentrations of Pb(NO(3))(2) and glucose 6-phosphate, showed that lead does not interfere with glucose 6-phosphatase activity. 2. Discontinuous sucrose-density-gradient centrifugation of microsomal fractions which had previously been incubated with various amounts of Pb(NO(3))(2) and glucose 6-phosphate showed that it is possible to subfractionate both smooth- and rough-microsomal fractions into several bands, owing to a differential modification of the density of the microsomal vesicles by the trapping of lead phosphate within them. 3. When the material in the bands obtained by density-gradient centrifugation of incubated microsomal fractions was assayed for glucose 6-phosphatase activity, it was found that the modification of the density of the microsomal fractions was directly related to their relative enrichment in glucose 6-phosphatase activity. Control experiments, in which microsomal fractions were incubated with Pb(NO(3))(2) and glucose 6-phosphate and then treated with EDTA, showed that the subfractionation was not due to aggregation of microsomal vesicles, lead and glucose 6-phosphate. Thus the resolution of microsomal preparations into subfractions with different glucose 6-phosphatase activities is interpreted as indicating heterogeneity of glucose 6-phosphatase distribution in the microsomal vesicles. 4. Electron micrographs of both smooth- and rough-microsomal subfractions show deposits of lead phosphate within the microsomal vesicles. The frequency and extent of these deposits correlate with the different amounts of glucose 6-phosphatase activity measured biochemically. 5. The nature of the heterogeneous distribution of glucose 6-phosphatase is discussed and the more general applicability of the technique for studying membrane fractions containing a heterogeneous distribution of phosphatases is indicated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353089"}
{"pmid": "4353088", "title": "A comparison of D-inositol 1:2-cyclic phosphate 2-phosphohydrolase with other phosphodiesterases of kidney.", "content": "A comparison of D-inositol 1:2-cyclic phosphate 2-phosphohydrolase with other phosphodiesterases of kidney. 1. The ability to hydrolyse various phosphodiesterase substrates was examined in subcellular fractions of rat kidney and in serial slices of the kidneys of mouse, rat, guinea pig and ox cut from the cortex perimeter inwards. 2. d-Inositol 1:2-cyclic phosphate 2-phosphohydrolase could be clearly distinguished from phosphodiesterases which hydrolyse 2':3'- and 3':5'-cyclic AMP and p-nitrophenyl thymidine 5'-phosphate (phosphodiesterase I). The hydrolysis of sn-glycero-3-phosphorylcholine showed a distribution identical with that of particle-bound d-inositol 1:2-cyclic phosphate 2-phosphodiesterase, but there was a 30-fold difference in the ratio of enzyme activities between the rat and guinea pig. 3. In rat and mouse kidney, d-inositol 1:2-cyclic phosphate 2-phosphohydrolase is virtually all membrane bound and in the outer cortex, whereas in guinea-pig kidney the enzyme is almost entirely soluble and located throughout the kidney tissue. Some properties of the soluble enzyme are described. 4. Distribution and histochemical studies indicated that in the rat and mouse, phosphodiesterase I is associated with the brush borders of the straight portion (pars recta) of the proximal tubule, whereas inositol 1:2-cyclic phosphate 2-phosphohydrolase and probably glycerylphosphorylcholine diesterase are associated with the brush borders of the convoluted part of the tubule (pars convoluta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353088"}
{"pmid": "4353091", "title": "The pattern of methylated purines formed in DNA of intact and regenerating liver of rats treated with the carcinogen dimethylnitrosamine.", "content": "The pattern of methylated purines formed in DNA of intact and regenerating liver of rats treated with the carcinogen dimethylnitrosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353091"}
{"pmid": "4353092", "title": "The synthesis of DNA associated with the nuclear membrane of guinea pig adrenal cells.", "content": "The synthesis of DNA associated with the nuclear membrane of guinea pig adrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353092"}
{"pmid": "4353093", "title": "An investigation of the phosphoprotein of the bovine dentin matrix.", "content": "An investigation of the phosphoprotein of the bovine dentin matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353093"}
{"pmid": "4353095", "title": "The interrelationships between vitamin D parathyroid hormone and calcitonin.", "content": "The interrelationships between vitamin D parathyroid hormone and calcitonin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353095"}
{"pmid": "4353094", "title": "Protein hydrophobicity and lipid--protein interaction.", "content": "Protein hydrophobicity and lipid--protein interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353094"}
{"pmid": "4353096", "title": "Some indicators of myocardial metabolism in complications caused by heterogeneous blood transfusion.", "content": "Some indicators of myocardial metabolism in complications caused by heterogeneous blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353096"}
{"pmid": "4353097", "title": "The ATP pool in Escherichia coli K 12 strains bearing the R1 plasmid.", "content": "The ATP pool in Escherichia coli K 12 strains bearing the R1 plasmid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353097"}
{"pmid": "4353099", "title": "Pregnant donkey's serum-induced ovulation in immature mice.", "content": "Pregnant donkey's serum-induced ovulation in immature mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353099"}
{"pmid": "4353100", "title": "Isolation of enteroviruses from sheep.", "content": "Isolation of enteroviruses from sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353100"}
{"pmid": "4353098", "title": "Effect of contraceptive suture on biochemical composition of uterine fluid of protein deficient rats.", "content": "Effect of contraceptive suture on biochemical composition of uterine fluid of protein deficient rats. To study the effect of a protein deficient diet on the biochemical composition and the volume of uterine fluid, 18 rats were maintained on a protein deficient diet and 18 rats on a normal diet.  A surgical silk suture was inserted into the right uterine horn of each rat.  After ovariectomy followed by rest of 7 days and injection of 50 mgm estradiol dipropionate daily for 7 days, the animals were sacrificed and the luminal fluid aspirated and studied.  The presence of the silk suture led to an increase in the amount of albumin present in the fluid.  There were no other alterations of biochemical composition of fluid attributable to the IUD or dietary protein deficiency.  In vivo incorporation of d1-valine-1-carbon-14 into protein lactic acid glycogen, acid-soluble phosphorus, and phosphatase activity was not affected by the presence of the sutures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353098"}
{"pmid": "4353101", "title": "Effects of some divalent cations on sympathetic ganglion function.", "content": "Effects of some divalent cations on sympathetic ganglion function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353101"}
{"pmid": "4353105", "title": "Biochemical aspects concerning adenine nucleotides and some related enzymes in the concomitant action of cephalin and serotonin of the blood platelets.", "content": "Biochemical aspects concerning adenine nucleotides and some related enzymes in the concomitant action of cephalin and serotonin of the blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353105"}
{"pmid": "4353102", "title": "Release of enzymes from a rat liver lysosome fraction: inhibition by catecholamines and cyclic3', 5'-adenosine monophosphate, stimulation by cholinergic agents and cyclic 3', 5'-guanosine monophosphate.", "content": "Release of enzymes from a rat liver lysosome fraction: inhibition by catecholamines and cyclic3', 5'-adenosine monophosphate, stimulation by cholinergic agents and cyclic 3', 5'-guanosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353102"}
{"pmid": "4353134", "title": "A modified pancreaticoduodenectomy.", "content": "A modified pancreaticoduodenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353134"}
{"pmid": "4353133", "title": "The origin, hormonal nature, and action of hepatotrophic substances in portal venous blood.", "content": "The origin, hormonal nature, and action of hepatotrophic substances in portal venous blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353133"}
{"pmid": "4353140", "title": "Some functional aspects of the plasma apolipoproteins.", "content": "Some functional aspects of the plasma apolipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353140"}
{"pmid": "4353146", "title": "Renin-angiotensin in extrarenal tissues.", "content": "Renin-angiotensin in extrarenal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353146"}
{"pmid": "4353158", "title": "Ultrastructural studies on cell degeneration in the mouse uterovaginal anlage.", "content": "Ultrastructural studies on cell degeneration in the mouse uterovaginal anlage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353158"}
{"pmid": "4353159", "title": "Effects of different hormones on the zoning and sinusoids of the adrenal gland.", "content": "Effects of different hormones on the zoning and sinusoids of the adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353159"}
{"pmid": "4353160", "title": "The actions of cyclic nucleotides on the toad bladder.", "content": "The actions of cyclic nucleotides on the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353160"}
{"pmid": "4353161", "title": "Regulation of gene transcription in Escherichia coli by cyclic AMP.", "content": "Regulation of gene transcription in Escherichia coli by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353161"}
{"pmid": "4353163", "title": "The role of cyclic AMP in the control of fluid secretion.", "content": "The role of cyclic AMP in the control of fluid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353163"}
{"pmid": "4353162", "title": "Role of cyclic AMP in the action of neurohypophyseal hormones on kidney.", "content": "Role of cyclic AMP in the action of neurohypophyseal hormones on kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353162"}
{"pmid": "4353165", "title": "The effect of cholera toxin on intestinal adenyl cyclase.", "content": "The effect of cholera toxin on intestinal adenyl cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353165"}
{"pmid": "4353164", "title": "Role of cyclic AMP in the regulation of gastric secretion in dogs and humans.", "content": "Role of cyclic AMP in the regulation of gastric secretion in dogs and humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353164"}
{"pmid": "4353166", "title": "Cyclic AMP and vascular smooth muscle.", "content": "Cyclic AMP and vascular smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353166"}
{"pmid": "4353167", "title": "Cyclic AMP as a first messenger.", "content": "Cyclic AMP as a first messenger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353167"}
{"pmid": "4353168", "title": "Studies on the possible role of cyclic AMP in drug-induced coronary vasodilatation.", "content": "Studies on the possible role of cyclic AMP in drug-induced coronary vasodilatation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353168"}
{"pmid": "4353170", "title": "Role of cyclic AMP in platelet function.", "content": "Role of cyclic AMP in platelet function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353170"}
{"pmid": "4353169", "title": "Role of cyclic AMP and Ca++ in metabolic and mechanical events in smooth muscle.", "content": "Role of cyclic AMP and Ca++ in metabolic and mechanical events in smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353169"}
{"pmid": "4353171", "title": "The positive inotropic effect of cyclic AMP.", "content": "The positive inotropic effect of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353171"}
{"pmid": "4353173", "title": "Effect of dibutyryl cyclic GMP on cultured beating rat heart cells.", "content": "Effect of dibutyryl cyclic GMP on cultured beating rat heart cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353173"}
{"pmid": "4353172", "title": "The role of cyclic AMP in the inotropic response to isoprenaline and glucagon.", "content": "The role of cyclic AMP in the inotropic response to isoprenaline and glucagon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353172"}
{"pmid": "4353174", "title": "Inotropic and chronotropic effects of dibutyryl cyclic AMP.", "content": "Inotropic and chronotropic effects of dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353174"}
{"pmid": "4353175", "title": "The role of cyclic AMP in visual excitation.", "content": "The role of cyclic AMP in visual excitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353175"}
{"pmid": "4353176", "title": "On the mechanism of action of cyclic AMP and its role in synaptic transmission.", "content": "On the mechanism of action of cyclic AMP and its role in synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353176"}
{"pmid": "4353177", "title": "Cyclic AMP-dependent protein kinases from skeletal muscle and liver.", "content": "Cyclic AMP-dependent protein kinases from skeletal muscle and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353177"}
{"pmid": "4353178", "title": "Neuroendocrine control of the cyclic AMP system of brain and pineal gland.", "content": "Neuroendocrine control of the cyclic AMP system of brain and pineal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353178"}
{"pmid": "4353181", "title": "Cyclic AMP in the rat brain: microwave irradiation as a means of tissue fixation.", "content": "Cyclic AMP in the rat brain: microwave irradiation as a means of tissue fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353181"}
{"pmid": "4353180", "title": "Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells.", "content": "Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353180"}
{"pmid": "4353179", "title": "Regulation of cyclic AMP metabolism in cultured cells of the nervous system.", "content": "Regulation of cyclic AMP metabolism in cultured cells of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353179"}
{"pmid": "4353182", "title": "Regulation of brain phosphodiesterase activity: Ca++ plus Mg++ -dependent phosphodiesterase and its activating factor from rat brain.", "content": "Regulation of brain phosphodiesterase activity: Ca++ plus Mg++ -dependent phosphodiesterase and its activating factor from rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353182"}
{"pmid": "4353183", "title": "Prostaglandin--adenyl cyclase relationships.", "content": "Prostaglandin--adenyl cyclase relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353183"}
{"pmid": "4353184", "title": "The role of cyclic AMP in activation of hormone-sensitive lipase of adipose tissue.", "content": "The role of cyclic AMP in activation of hormone-sensitive lipase of adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353184"}
{"pmid": "4353185", "title": "Cyclic AMP and prostaglandins in hormone action.", "content": "Cyclic AMP and prostaglandins in hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353185"}
{"pmid": "4353186", "title": "Functional relations between cyclic AMP, prostaglandins, and luteinizing hormone in rat pituitary and ovary.", "content": "Functional relations between cyclic AMP, prostaglandins, and luteinizing hormone in rat pituitary and ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353186"}
{"pmid": "4353188", "title": "The role of cyclic AMP in lysosome mobilization and their nucleotropic translocation in steroid hormonal target cells.", "content": "The role of cyclic AMP in lysosome mobilization and their nucleotropic translocation in steroid hormonal target cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353188"}
{"pmid": "4353187", "title": "A study of the bioloical activity and resistance to phosphodiesterase of some derivatives and analogues of cyclic AMP.", "content": "A study of the bioloical activity and resistance to phosphodiesterase of some derivatives and analogues of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353187"}
{"pmid": "4353190", "title": "Levels of cyclic AMP and rate of fat mobilizing lipolysis in human adipose tissue in response to different adrenergic stimulators.", "content": "Levels of cyclic AMP and rate of fat mobilizing lipolysis in human adipose tissue in response to different adrenergic stimulators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353190"}
{"pmid": "4353189", "title": "Studies on the role of cyclic AMP in human lipolysis.", "content": "Studies on the role of cyclic AMP in human lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353189"}
{"pmid": "4353191", "title": "The role of cyclic AMP in the control of hepatic glucose production by glucagon and insulin.", "content": "The role of cyclic AMP in the control of hepatic glucose production by glucagon and insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353191"}
{"pmid": "4353192", "title": "Determination of alpha-quartz in the respirable portion of airborne particulates by X-ray diffraction.", "content": "Determination of alpha-quartz in the respirable portion of airborne particulates by X-ray diffraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353192"}
{"pmid": "4353194", "title": "Animal model of human disease. Liver cell carcinoma, hepatocellular carcinoma, hepatoma.", "content": "Animal model of human disease. Liver cell carcinoma, hepatocellular carcinoma, hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353194"}
{"pmid": "4353195", "title": "The functional significance of surface structures on lymphocytes.", "content": "The functional significance of surface structures on lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353195"}
{"pmid": "4353193", "title": "Immunologic properties of ferritin.", "content": "Immunologic properties of ferritin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353193"}
{"pmid": "4353199", "title": "Hepatic arterial patency and complications after catheterization for infusion chemotherapy.", "content": "Hepatic arterial patency and complications after catheterization for infusion chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353199"}
{"pmid": "4353198", "title": "Muscular tumors of the stomach: clinical and pathological study of 113 cases.", "content": "Muscular tumors of the stomach: clinical and pathological study of 113 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353198"}
{"pmid": "4353205", "title": "Abdominal aortography in the newborn via the umbilical artery.", "content": "Abdominal aortography in the newborn via the umbilical artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353205"}
{"pmid": "4353206", "title": "Murine erythroblastosis by a novel viral agent.", "content": "Murine erythroblastosis by a novel viral agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353206"}
{"pmid": "4353207", "title": "Chemotherapy of lymph node metastasis by thigh and footpad inoculation of mouse leukemia L-1210 cells.", "content": "Chemotherapy of lymph node metastasis by thigh and footpad inoculation of mouse leukemia L-1210 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353207"}
{"pmid": "4353208", "title": "Molecular weight of cytochrome oxidase.", "content": "Molecular weight of cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353208"}
{"pmid": "4353209", "title": "A rabies-induced serum factor inhibiting Rous sarcoma virus in chicks.", "content": "A rabies-induced serum factor inhibiting Rous sarcoma virus in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353209"}
{"pmid": "4353210", "title": "Temperature-sensitive mutants of vesicular stomatitis virus; homology and nomenclature.", "content": "Temperature-sensitive mutants of vesicular stomatitis virus; homology and nomenclature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353210"}
{"pmid": "4353211", "title": "Host range conversion of the murine sarcoma-leukaemia complex.", "content": "Host range conversion of the murine sarcoma-leukaemia complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353211"}
{"pmid": "4353212", "title": "The role of antibody and host cells in the resistance of mice against infection by coxsackie B-3 virus.", "content": "The role of antibody and host cells in the resistance of mice against infection by coxsackie B-3 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353212"}
{"pmid": "4353213", "title": "Evidence for a group protein in foot-and-mouth disease virus particles.", "content": "Evidence for a group protein in foot-and-mouth disease virus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353213"}
{"pmid": "4353215", "title": "Properties of mouse embryo cells infected with murine sarcoma virus and simian virus 40 simultaneously in vitro.", "content": "Properties of mouse embryo cells infected with murine sarcoma virus and simian virus 40 simultaneously in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353215"}
{"pmid": "4353214", "title": "Haemagglutination by type SAT 2 foot-and-mouth disease viruses.", "content": "Haemagglutination by type SAT 2 foot-and-mouth disease viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353214"}
{"pmid": "4353216", "title": "Restoration of the fusion activity of L cell-borne Sendai virus by trypsin.", "content": "Restoration of the fusion activity of L cell-borne Sendai virus by trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353216"}
{"pmid": "4353217", "title": "Primary carcinoma of the liver: a study of 282 cases in Ugandan Africans.", "content": "Primary carcinoma of the liver: a study of 282 cases in Ugandan Africans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353217"}
{"pmid": "4353218", "title": "Actions of 1,25-dihydroxycholecalciferol in patients with hypophosphatemic, vitamin-D-resistant rickets.", "content": "Actions of 1,25-dihydroxycholecalciferol in patients with hypophosphatemic, vitamin-D-resistant rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353218"}
{"pmid": "4353219", "title": "Familial hypophosphatemia: the dilemma of treatment.", "content": "Familial hypophosphatemia: the dilemma of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353219"}
{"pmid": "4353222", "title": "Metabolism of the myocardium at cellular level.", "content": "Metabolism of the myocardium at cellular level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353222"}
{"pmid": "4353224", "title": "Ventilatory pumping of human pulmonary lymphatic vessels.", "content": "Ventilatory pumping of human pulmonary lymphatic vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353224"}
{"pmid": "4353223", "title": "The role of diet in the management of hyperlipoproteinaemias.", "content": "The role of diet in the management of hyperlipoproteinaemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353223"}
{"pmid": "4353221", "title": "Time course of decrease in blood pressure and in blood pressure response to vasopressor agents during pregnancy in the rat.", "content": "Time course of decrease in blood pressure and in blood pressure response to vasopressor agents during pregnancy in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353221"}
{"pmid": "4353225", "title": "Delay in bone age in children with cyanotic congenital heart disease.", "content": "Delay in bone age in children with cyanotic congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353225"}
{"pmid": "4353226", "title": "Use of ultrasonography to follow regression of theca lutein cysts.", "content": "Use of ultrasonography to follow regression of theca lutein cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353226"}
{"pmid": "4353228", "title": "Granuloma formation.", "content": "Granuloma formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353228"}
{"pmid": "4353229", "title": "Contraception.", "content": "Contraception. The article reviews the putative effects of oral contraceptives on the metabolism, hepatic function, thyroid gland, adrenal gland, carbohydrate and lipid metabolism, blood pressure and coagulation, and thromboembolic disease.  Assessing risks by interpretation of mortality rates is briefly discussed and it is concluded that the risks in oral contraception are acceptable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353229"}
{"pmid": "4353232", "title": "Suppression of the defect in cell division in the histidine regulatory mutants of Salmonella typhimurium.", "content": "Suppression of the defect in cell division in the histidine regulatory mutants of Salmonella typhimurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353232"}
{"pmid": "4353233", "title": "A case of juvenile angiofibroma.", "content": "A case of juvenile angiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353233"}
{"pmid": "4353234", "title": "The amino acid sequence of cytochrome c from Nigella damascena L. (love-in-a-mist).", "content": "The amino acid sequence of cytochrome c from Nigella damascena L. (love-in-a-mist). The amino acid sequence of cytochrome c from Nigella damascena L. was determined on 0.2mumol of protein. Peptides from a single chymotryptic digest were analysed by the dansyl-Edman procedure. These peptides were ordered by reference to the sequences of other plant cytochromes c, assuming that the Nigella cytochrome is homologous with the other cytochromes. Many of the Nigella peptides were one or two residues short when compared with the corresponding chymotryptic peptides from other plant cytochromes c. These residues are assumed to have been removed by an endogenous carboxypeptidase, and the identification and placing of these residues is entirely based on homology. These residues are numbered 3, 18, 42, 43, 44, 54, 67, 72, 73, 82 and 105. A number of other positions are almost entirely placed by homology. These are positions which could not be placed definitely by dansyl-Edman analysis or by dansylation after digestion with carboxypeptidase A, and are numbered 14, 15, 16, 39, 40, 85, 86, 87 and 88. Except for residue 15, all residues based entirely, or nearly so, on homology have been previously found invariant in sequences of plant cytochromes c. Experimental details are given in a supplementary paper that has been deposited as Supplementary Publication SUP 50017, at the National Lending Library for Science and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1973) 131, 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353234"}
{"pmid": "4353235", "title": "The formation of a  -(1 leads to 4)-D-galactan chain catalysed by a Phaseolus aureus enzyme.", "content": "The formation of a  -(1 leads to 4)-D-galactan chain catalysed by a Phaseolus aureus enzyme. With a particulate enzyme preparation from Phaseolus aureus hypocotyls, UDP-alpha-d-[U-(14)C]galactose served as a precursor for a number of products. One of these products was characterized as a beta-(1-->4)-linked galactan. The ADP-, GDP-, TDP- and CDP- derivatives of alpha-d-galactose did not serve as biosynthetic precursors for any products insoluble in 70% ethanol, nor as substrates for a sugar nucleotide 4-epimerase which is present in the particulate enzyme preparation. The (14)C-labelled beta-(1-->4)-galactan is alkali-insoluble and was characterized by analysis of partial acetolysis products. The labelling pattern of the [(14)C]oligosaccharides derived from acetolysis indicates that (1) only slightly more than two [(14)C]galactose moieties are added to the growing polysaccharide chain on average, and (2) these additions take place at the reducing end of the polysaccharide chain. The radioactive beta-(1-->4)-linked galactan chain represented 8.5% of the radioactivity initially added, and 20% of the water- and butanol-insoluble products derived from UDP-alpha-d-[(14)C]galactose. Total hydrolysis of the alkali-insoluble fraction of Phaseolus aureus hypocotyl yielded d-glucose and d-mannose in a 5:1 ratio but no detectable quantities of d-galactose. A trace quantity of a radioactive disaccharide, identified as (1-->3)-linked galactobiose, was isolated from the partial acetolysate of the alkali-insoluble [(14)C]polysaccharide material. Also isolated from this partial acetolysate was a C-1 derivative of [(14)C]galactose, which could not be identified. An alkali-soluble galactose-containing polysaccharide was also synthesized in this enzymic reaction, and represented 20% of the water- and butanol-insoluble products derived from UDP-alpha-d-[(14)C]galactose. The spectrum of radioactive oligosaccharides produced by partial acetolysis of this alkali-soluble polysaccharide material was different from that obtained from the alkali-insoluble polysaccharide, indicating a different structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353235"}
{"pmid": "4353236", "title": "The association between phosphatidylinositol phosphodiesterase activity and a specific subunit of microtubular protein in rat brain.", "content": "The association between phosphatidylinositol phosphodiesterase activity and a specific subunit of microtubular protein in rat brain. 1. Supernatant proteins from rat brain were separated into two fractions containing phosphatidylinositol phosphodiesterase activity by chromatography on DEAE-Sephadex A-50. 2. The first fraction sediments in linear sucrose density gradients in two bands corresponding to molecular weights of 66000 and 36000. There was presumptive evidence that the lighter protein constituted the monomeric form of the enzyme. The second fraction sediments predominantly as a single protein of molecular weight 86000. 3. Treatment of rat brain supernatant with [(3)H]colchicine abolished the second DEAE-Sephadex peak and removed the lighter protein from the first peak. These proteins emerged in the same position as the protein binding [(3)H]colchicine at high salt concentration; phospholipase activity was recovered from linear sucrose density gradients in positions corresponding to molecular weights 88000 and 43000, together with an aggregate of molecular weight 140000. Electrophoresis on sodium dodecyl sulphate-urea-polyacrylamide gels of this fraction revealed only three proteins: the alpha and beta-subunits of microtubular protein, of molecular weights 56000 and 52000 respectively, and a protein of molecular weight 38000. 4. A sample of microtubular protein from mouse, labelled in vivo with [(3)H]proline and (32)P(i), was added to rat brain supernatant together with an equal amount of the same microtubular protein treated with cyclic AMP and [gamma-(32)P]ATP and the mixture subsequently characterized by ion-exchange chromatography. Some phospholipase activity characteristic of the second peak from DEAE-Sephadex was associated with one fraction of added microtubular protein. This fraction was identified on the basis of the (3)H:(32)P ratio as the beta subunit of the protein treated with ATP and cyclic AMP. The subunit of added microtubular protein untreated with nucleotides was not associated with phospholipase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353236"}
{"pmid": "4353237", "title": "A collagenase in extracts of the invertebrate Bipalium kewense.", "content": "A collagenase in extracts of the invertebrate Bipalium kewense. The localization, isolation and partial characterization of a collagenolytic enzyme from the land planarian Bipalium kewense is described. This enzyme can be obtained by direct extraction of the organism, and can be separated from non-collagenous proteolytic activity by (NH(4))(2)SO(4) precipitation and Sephadex-gel chromatography. Its mode of attack on collagen and sensitivity to a variety of inhibitors indicate that this enzyme differs from vertebrate collagenases and a previously described invertebrate collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353237"}
{"pmid": "4353239", "title": "Lack of temperature-sensitivity of rat liver pyruvate kinase.", "content": "Lack of temperature-sensitivity of rat liver pyruvate kinase. Rat liver pyruvate kinase, prepared by Sephadex treatment of a 10(5)g supernatant in phosphate buffer, is quite stable and gives reproducible results when a variety of parameters are altered in the enzyme assay. Incubation of this preparation at 25 degrees C or 0-2 degrees C has no effect on the activation by fructose 1,6-diphosphate or inhibition by ATP or alanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353239"}
{"pmid": "4353240", "title": "A radiographic survey of monumental masonry workers in Aberdeen.", "content": "A radiographic survey of monumental masonry workers in Aberdeen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353240"}
{"pmid": "4353238", "title": "A comparaive study of the effects of chemical modification on the immunochemical and optical properties of human plasma low-density lipoprotein(s) and apoproteins.", "content": "A comparaive study of the effects of chemical modification on the immunochemical and optical properties of human plasma low-density lipoprotein(s) and apoproteins. 1. The structure of human plasma low-density lipoprotein(s) [LD lipoprotein(s)] was investigated by several immunological and optical techniques. The effects of delipidation and of chemical modification by 3-carboxypropionylation, acetylation, diazotization and amidination were examined. A sensitive double-antibody radioimmunoassay for human LD lipoproteins is presented and is used to assess the extent of immunochemical modification. A computer best-fit analysis is used to analyse circular-dichorism (c.d.) spectra. These methods permit comparisons of the relative effects of chemical modification and delipidation of LD lipoprotein under similar experimental conditions. 2. 3-Carboxypropionylation, acetylation or diazotization produces qualitative and quantitative changes in the immunochemical properties of LD lipoprotein. Amidination causes minor changes detected by radioimmunoassay but not by double-diffusion experiments. In general, the order of effectiveness in displacing (125)I-labelled LD lipoprotein is amidinated>diazo or acetyl>3-carboxypropionyl derivatives. 3. The order of the extent of conformational alteration induced in apoLD lipoprotein and LD lipoprotein, as judged by c.d. analyses, was 3-carboxypropionylation>diazotization>acetylation or amidination. 4. Delipidation of LD lipoprotein results in immunological alterations that are qualitatively detected by antisera to LD lipoprotein. Four of five antisera to apoLD lipoprotein form precipitin lines of identity between native LD lipoprotein and apoLD lipoprotein in double-diffusion experiments. An anti-(apoLD lipoprotein) serum that forms precipitin lines of complete identity between LD lipoprotein and apoLD lipoprotein reacts differently with these two antigens in radioimmunoassay. ApoLD lipoprotein is only one-fourth to one-half as effective as LD lipoprotein, on a protein basis, in the displacement of (125)I-labelled LD lipoprotein from this anti-(apoLD lipoprotein). 5. Conformational analysis indicates that apoLD lipoprotein retains a high proportion of the structural integrity of the native lipoprotein. Delipidation induces a small decrease in the content of beta-structure and a small increase in disordered structure, without greatly affecting the alpha-helical content. Chemical modification produces more severe conformational changes of apoLD lipoprotein than of LD lipoprotein. Computer analysis of the c.d. spectra of apoLD lipoprotein indicates that addition of high concentrations of sodium decyl sulphate abolishes most of the beta-conformation concomitant with increases in alpha-helical and disordered structure. 6. There is parallelism between the alteration of the charge of LD lipoprotein and apoLD lipoprotein and the extent of immunochemical and conformational changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353238"}
{"pmid": "4353241", "title": "The effects of pargyline on overflow of transmitter and uptake of noradrenaline in the cat spleen.", "content": "The effects of pargyline on overflow of transmitter and uptake of noradrenaline in the cat spleen. 1. Twenty minutes after the addition of pargyline (5 x 10(-4)M) to blood perfusing the isolated spleen of the cat, the overflow of transmitter resulting from stimulation of the sympathetic nerves increased 2.3-3-fold. Lower doses of pargyline did not significantly affect overflow.2. Monoamine oxidase activity, measured with either radioactively labelled tyramine or noradrenaline as substrate, was almost completely inhibited by doses of pargyline in the range of 10(-4)M to 5 x 10(-4)M. Inhibition of enzyme activity was not correlated with the effect on overflow. Pargyline had only a slight inhibitory effect on catechol-O-methyl transferase.3. Uptake of a 1 mug injection (pulse) of labelled noradrenaline, following pargyline (5 x 10(-4)M), was increased to 199.1% of that found in control experiments.4. Pargyline significantly reduced the vascular responses to nerve stimulation but had no significant effect on capsular responses.5. The inhibitor had no effect on resting overflow of labelled noradrenaline from the spleen but doubled the overflow of labelled noradrenaline following nerve stimulation.6. It is suggested that the effect of pargyline on overflow is due to increased release of transmitter during nerve stimulation.7. The possible clinical significance of these findings is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353241"}
{"pmid": "4353242", "title": "Effect of phospholipase C on calcium release from epithelia treated with antidiuretic hormone.", "content": "Effect of phospholipase C on calcium release from epithelia treated with antidiuretic hormone. 1. Addition of antidiuretic hormone (ADH) to the bladders of toads (Bufo marinus) preloaded with (45)Ca causes an increase in the rate of calcium efflux.2. Pretreatment of the serosal surfaces of bladders with phospholipase C prevents the action of ADH on calcium efflux.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353242"}
{"pmid": "4353243", "title": "Does methaqualone cause neuropathy?", "content": "Does methaqualone cause neuropathy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353243"}
{"pmid": "4353244", "title": "Smooth muscle autoantibodies in infectious mononucleosis.", "content": "Smooth muscle autoantibodies in infectious mononucleosis. Smooth muscle antibodies (S.M.A.) were found in the sera of 81% of 126 patients over 10 years old with seropositive infectious mononucleosis tested within one month of onset. In 27 patients presenting clinically with infectious mononucleosis but having negative Paul-Bunnell tests the incidence of S.M.A. was 44%. In children 10 years of age or less in these two categories S.M.A. were present in 75% and 25% respectively, while in children of similar age not suspected of having infectious mononucleosis the incidence of S.M.A. was 10%. Among 45 adults with past histories of seropositive infectious mononucleosis more than one year before the incidence of S.M.A. was 33%, in contrast to 14% in 98 subjects with a negative history for infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353244"}
{"pmid": "4353249", "title": "Dextran-coated charcoal technique to make the hormone-free serum as a diluent for standard curve of radioimmunoassay.", "content": "Dextran-coated charcoal technique to make the hormone-free serum as a diluent for standard curve of radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353249"}
{"pmid": "4353250", "title": "Effect of sex hormones on the activity of protein kinases in rat ventral prostate and uterus.", "content": "Effect of sex hormones on the activity of protein kinases in rat ventral prostate and uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353250"}
{"pmid": "4353253", "title": "Study on the systematic use of serial estimation of human placental lactogen (hPL) and human chorionic gonadotropin (hCG) for the management of trophoblastic neoplasia.", "content": "Study on the systematic use of serial estimation of human placental lactogen (hPL) and human chorionic gonadotropin (hCG) for the management of trophoblastic neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353253"}
{"pmid": "4353251", "title": "Effects of ACTH and its synthetic analogues on water balance in rats.", "content": "Effects of ACTH and its synthetic analogues on water balance in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353251"}
{"pmid": "4353252", "title": "Improvement by exogenous cyclic AMP of hereditary vasopressin-resistant diuresis in mice with normal adenyl cyclase system of the kidney cells.", "content": "Improvement by exogenous cyclic AMP of hereditary vasopressin-resistant diuresis in mice with normal adenyl cyclase system of the kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353252"}
{"pmid": "4353254", "title": "Operantly conditioned firing patterns of epileptic neurons in the monkey motor cortex.", "content": "Operantly conditioned firing patterns of epileptic neurons in the monkey motor cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353254"}
{"pmid": "4353256", "title": "Intrinsic connections of caudate neurons. Locally evoked intracellular responses.", "content": "Intrinsic connections of caudate neurons. Locally evoked intracellular responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353256"}
{"pmid": "4353255", "title": "Acoustic responses and plasticity of limbic units in cats.", "content": "Acoustic responses and plasticity of limbic units in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353255"}
{"pmid": "4353257", "title": "Spontaneous and evoked bioelectric activity in organized cerebellar tissue cultures.", "content": "Spontaneous and evoked bioelectric activity in organized cerebellar tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353257"}
{"pmid": "4353258", "title": "Recruitment of motor units in voluntary contraction of a finger muscle in man.", "content": "Recruitment of motor units in voluntary contraction of a finger muscle in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353258"}
{"pmid": "4353259", "title": "Firing rate of individual motor units in voluntary contraction of abductor digiti minimi muscle in man.", "content": "Firing rate of individual motor units in voluntary contraction of abductor digiti minimi muscle in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353259"}
{"pmid": "4353267", "title": "The inhibition mechanism of the cytochrome oxidase reaction. IV. The nature of the kinetically inactive complex of cytochrome oxidase with cyanide.", "content": "The inhibition mechanism of the cytochrome oxidase reaction. IV. The nature of the kinetically inactive complex of cytochrome oxidase with cyanide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353267"}
{"pmid": "4353266", "title": "Formation and decomposition of pyrophosphate related to bacterial photophosphorylation.", "content": "Formation and decomposition of pyrophosphate related to bacterial photophosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353266"}
{"pmid": "4353268", "title": "Role of oleate in the regulation of \"neutral\" rabbit liver fructose 1,6-diphosphatase activity.", "content": "Role of oleate in the regulation of \"neutral\" rabbit liver fructose 1,6-diphosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353268"}
{"pmid": "4353269", "title": "Interaction between adenosine triphosphate and glyceraldehyde 3-phosphate dehydrogenase. 3. Mechanism of action and metabolic control of the enzyme under simulated in vivo conditions.", "content": "Interaction between adenosine triphosphate and glyceraldehyde 3-phosphate dehydrogenase. 3. Mechanism of action and metabolic control of the enzyme under simulated in vivo conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353269"}
{"pmid": "4353271", "title": "Effect of beta-adrenergic catecholamines on sodium transport in turkey erythrocytes.", "content": "Effect of beta-adrenergic catecholamines on sodium transport in turkey erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353271"}
{"pmid": "4353270", "title": "Regulation of glyceraldehyde 3-phosphate dehydrogenase by phosphocreatine and adenosine triphosphate. IV. Factors affecting in vivo control of enzymatic activity.", "content": "Regulation of glyceraldehyde 3-phosphate dehydrogenase by phosphocreatine and adenosine triphosphate. IV. Factors affecting in vivo control of enzymatic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353270"}
{"pmid": "4353273", "title": "Specific binding of phosphorylated non-histone chromatin proteins to deoxyribonucleic acid.", "content": "Specific binding of phosphorylated non-histone chromatin proteins to deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353273"}
{"pmid": "4353272", "title": "L-Glycerol 3-phosphate dehydrogenases. II. Effects of phosphorylated compounds on nicotinamide adenine dinucleotide linked enzyme from rabbit liver.", "content": "L-Glycerol 3-phosphate dehydrogenases. II. Effects of phosphorylated compounds on nicotinamide adenine dinucleotide linked enzyme from rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353272"}
{"pmid": "4353274", "title": "Inactivation of melanocyte-stimulating hormone release-inhibiting factor by a manganese-stimulated bovine brain aminopeptidase.", "content": "Inactivation of melanocyte-stimulating hormone release-inhibiting factor by a manganese-stimulated bovine brain aminopeptidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353274"}
{"pmid": "4353275", "title": "Arginase isozymes of rat mammary gland, liver, and other tissues.", "content": "Arginase isozymes of rat mammary gland, liver, and other tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353275"}
{"pmid": "4353276", "title": "Expression of the mitochondrial genome in HeLa cells. XVII. Heterogeneity of isolated HeLa cell mitochondria as assayed for their enzymatic and in vivo biosynthetic activities.", "content": "Expression of the mitochondrial genome in HeLa cells. XVII. Heterogeneity of isolated HeLa cell mitochondria as assayed for their enzymatic and in vivo biosynthetic activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353276"}
{"pmid": "4353277", "title": "Plasma membrane cyclic adenosine 3':5'-monophosphate phosphodiesterase of cultured cells and its modification after trypsin treatment of intact cells.", "content": "Plasma membrane cyclic adenosine 3':5'-monophosphate phosphodiesterase of cultured cells and its modification after trypsin treatment of intact cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353277"}
{"pmid": "4353278", "title": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. XXXIX. Reconstitution of the third segment of oxidative phosphorylation.", "content": "Partial resolution of the enzymes catalyzing oxidative phosphorylation. XXXIX. Reconstitution of the third segment of oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353278"}
{"pmid": "4353279", "title": "Early events in glucocorticoid action. Activation of the steroid receptor and its subsequent specific nuclear binding studied in a cell-free system.", "content": "Early events in glucocorticoid action. Activation of the steroid receptor and its subsequent specific nuclear binding studied in a cell-free system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353279"}
{"pmid": "4353281", "title": "Neuroendocrine responses to physical and psychological stress.", "content": "Neuroendocrine responses to physical and psychological stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353281"}
{"pmid": "4353280", "title": "Nature of nuclear acceptor sites for glucocorticoid- and estrogen-receptor complexes.", "content": "Nature of nuclear acceptor sites for glucocorticoid- and estrogen-receptor complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353280"}
{"pmid": "4353282", "title": "Recruitment deafness: functional effect of priming-induced audiogenic seizures in mice.", "content": "Recruitment deafness: functional effect of priming-induced audiogenic seizures in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353282"}
{"pmid": "4353283", "title": "Genetic and enzymatic characterization of a conditional lethal mutant of Escherichia coli K12 with a temperature-sensitive DNA ligase.", "content": "Genetic and enzymatic characterization of a conditional lethal mutant of Escherichia coli K12 with a temperature-sensitive DNA ligase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353283"}
{"pmid": "4353284", "title": "Genetics and function of DNA ligase in Escherichia coli.", "content": "Genetics and function of DNA ligase in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353284"}
{"pmid": "4353286", "title": "Spontaneous skin potential responses during natural sleep in monkeys.", "content": "Spontaneous skin potential responses during natural sleep in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353286"}
{"pmid": "4353287", "title": "Interferon production by Bordetella pertussis components in rabbits and in rabbit cell cultures.", "content": "Interferon production by Bordetella pertussis components in rabbits and in rabbit cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353287"}
{"pmid": "4353288", "title": "Chronic lead nephropathy.", "content": "Chronic lead nephropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353288"}
{"pmid": "4353292", "title": "Molecular conformation of guanosine 3,'5-cyclic monophosphate.", "content": "Molecular conformation of guanosine 3,'5-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353292"}
{"pmid": "4353291", "title": "Incorporation of (1-14c)-oleic acid into neutral glycerides and phosphoglycerides of mouse brain.", "content": "Incorporation of (1-14c)-oleic acid into neutral glycerides and phosphoglycerides of mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353291"}
{"pmid": "4353290", "title": "Preferential labeling of phosphatidylcholine during phospholipid synthesis by bovine mammary tissue.", "content": "Preferential labeling of phosphatidylcholine during phospholipid synthesis by bovine mammary tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353290"}
{"pmid": "4353293", "title": "Post-tetanic potentiation and facilitation do not share a common calcium-dependent mechanism.", "content": "Post-tetanic potentiation and facilitation do not share a common calcium-dependent mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353293"}
{"pmid": "4353297", "title": "Windowless semiconductor radiation detectors for measurement of low-energy beta-emitters in vivo and in vitro.", "content": "Windowless semiconductor radiation detectors for measurement of low-energy beta-emitters in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353297"}
{"pmid": "4353301", "title": "Insomnia with sleep apnea: a new syndrome.", "content": "Insomnia with sleep apnea: a new syndrome. A new clinical syndrome, sleep apnea associated with insomnia, has been characterized. Repeated episodes of apnea occur during sleep. Onset of respiration is associated with general arousal and often complete awakening, with a resultant loss of sleep. An important clinical implication is that patients complaining only of insomnia may be suffering from this syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353301"}
{"pmid": "4353303", "title": "Photopic suppression of monkey's rod receptor potential, apparently by a cone-initiated lateral inhibition.", "content": "Photopic suppression of monkey's rod receptor potential, apparently by a cone-initiated lateral inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353303"}
{"pmid": "4353302", "title": "Plasma membranes: isolation from naturally fused and lysolecithin-treated muscle cells.", "content": "Plasma membranes: isolation from naturally fused and lysolecithin-treated muscle cells. A medium containing bicarbonate and calcium was used to isolate plasma membranes of cultured muscle cells. Membranes from differentiated myotubes, as well as the labile, largely unfused, lysolecithin-treated cells from the same culture could be isolated by identical manipulations. Adenylate cyclase of high specific activity was assayed in plasma membranes from both types of cells. Lysolecithin treatment apparently interferes with the metabolism and turnover of membrane phospholipids and thus prevents the natural fusion of muscle cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353302"}
{"pmid": "4353305", "title": "Ultradian rhythms in human telemetered gross motor activity.", "content": "Ultradian rhythms in human telemetered gross motor activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353305"}
{"pmid": "4353306", "title": "Circadian rhythms of free radical state concentrations in the organs of mice.", "content": "Circadian rhythms of free radical state concentrations in the organs of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353306"}
{"pmid": "4353307", "title": "Aftereffects of alcohol on the perception and control of pitch attitude during centripetal acceleration.", "content": "Aftereffects of alcohol on the perception and control of pitch attitude during centripetal acceleration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353307"}
{"pmid": "4353308", "title": "Herpes zoster in children with cancer.", "content": "Herpes zoster in children with cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353308"}
{"pmid": "4353309", "title": "Wilms tumor in right atrium.", "content": "Wilms tumor in right atrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353309"}
{"pmid": "4353310", "title": "Six year follow-up of a child with Bartter syndrome.", "content": "Six year follow-up of a child with Bartter syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353310"}
{"pmid": "4353311", "title": "Benign nasal tumor appearing as neonatal respiratory distress. First reported case of nasopharyngeal fibrous histiocytoma.", "content": "Benign nasal tumor appearing as neonatal respiratory distress. First reported case of nasopharyngeal fibrous histiocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353311"}
{"pmid": "4353312", "title": "Physiological psychology: sleep.", "content": "Physiological psychology: sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353312"}
{"pmid": "4353313", "title": "Instantaneous decompression and the skin.", "content": "Instantaneous decompression and the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353313"}
{"pmid": "4353316", "title": "24-Hour sleep patterns. A comparison between 2- to 3-year-old and 4- to 6-year-old children.", "content": "24-Hour sleep patterns. A comparison between 2- to 3-year-old and 4- to 6-year-old children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353316"}
{"pmid": "4353315", "title": "Chinese psychiatry. A visit to a Chinese mental hospital.", "content": "Chinese psychiatry. A visit to a Chinese mental hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353315"}
{"pmid": "4353317", "title": "Sleep EEG studies in untreated, long-term schizophrenic patients.", "content": "Sleep EEG studies in untreated, long-term schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353317"}
{"pmid": "4353319", "title": "The surgical management of amoebiasis in children.", "content": "The surgical management of amoebiasis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353319"}
{"pmid": "4353318", "title": "Barbiturate-induced transmitter release at a frog neuromuscular junction.", "content": "Barbiturate-induced transmitter release at a frog neuromuscular junction. 1. The influence of barbiturates on neuromuscular transmission at end-plates of frog sartorius muscles was investigated electrophysiologically on preparations bathed in Ringer solution containing a low concentration of calcium and a high concentration of magnesium.2. Effects of a convulsant barbiturate, 5-(2-cyclohexylideneëthyl)-5-ethyl barbituric acid (CHEB), were compared with those of phenobarbitone.3. CHEB and phenobarbitone increased the mean quantum content of the end-plate potentials and decreased the mean amplitude of the miniature end-plate potentials.4. Both barbiturates enhanced the duration of the nerve-terminal action potential and had little or no effect on the effective resistance of the skeletal muscle membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353318"}
{"pmid": "4353324", "title": "Pituitary ACTH and GH content associated with the loss of acidophils following thyroidectomy.", "content": "Pituitary ACTH and GH content associated with the loss of acidophils following thyroidectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353324"}
{"pmid": "4353325", "title": "Relation between changes in the acid-base and the energy metabolism of the brain in hepatic coma.", "content": "Relation between changes in the acid-base and the energy metabolism of the brain in hepatic coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353325"}
{"pmid": "4353326", "title": "Changes in collagen with age. V. Modification of mouse skin collagen by whole body x-irradiation.", "content": "Changes in collagen with age. V. Modification of mouse skin collagen by whole body x-irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353326"}
{"pmid": "4353328", "title": "Pathophysiology of human tears.", "content": "Pathophysiology of human tears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353328"}
{"pmid": "4353329", "title": "Pathophysiology and diagnosis of tear film abnormalities. Surfacing abnormalities.", "content": "Pathophysiology and diagnosis of tear film abnormalities. Surfacing abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353329"}
{"pmid": "4353330", "title": "Renal stone crystals grown in gel systems. A preliminary report.", "content": "Renal stone crystals grown in gel systems. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353330"}
{"pmid": "4353332", "title": "Oxidation of a ferrocytochrome c in the crystalline state--structural change and anion binding.", "content": "Oxidation of a ferrocytochrome c in the crystalline state--structural change and anion binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353332"}
{"pmid": "4353331", "title": "The sucrose-gap technique. Autonomic drugs and electrical characteristics of the ureter.", "content": "The sucrose-gap technique. Autonomic drugs and electrical characteristics of the ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353331"}
{"pmid": "4353333", "title": "Inhibitory effect of Na+ on phosphorylation of proteins in brain microsomes and synaptic membranes.", "content": "Inhibitory effect of Na+ on phosphorylation of proteins in brain microsomes and synaptic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353333"}
{"pmid": "4353334", "title": "Ferredoxin-linked nitrate reductase from Clostridium perfringens.", "content": "Ferredoxin-linked nitrate reductase from Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353334"}
{"pmid": "4353335", "title": "Combined transmission electron microscopy and X-ray micro-analysis of ultrathin frozen dried sections--an investigation to determine the normal elemental composition of mammalian tissue.", "content": "Combined transmission electron microscopy and X-ray micro-analysis of ultrathin frozen dried sections--an investigation to determine the normal elemental composition of mammalian tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353335"}
{"pmid": "4353336", "title": "Fluidity of phospholipid bilayers and membranes after exposure to osmium tetroxide and gluteraldehyde.", "content": "Fluidity of phospholipid bilayers and membranes after exposure to osmium tetroxide and gluteraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353336"}
{"pmid": "4353337", "title": "Subcellular site of the phosphatidylinositol effect. Distribution on density gradients of labelled lipids from resting and active sympathetic ganglia of the rat.", "content": "Subcellular site of the phosphatidylinositol effect. Distribution on density gradients of labelled lipids from resting and active sympathetic ganglia of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353337"}
{"pmid": "4353338", "title": "Influence of neuroleptic drugs and apomorphine on dopamine-sensitive adenylate cyclase of retina.", "content": "Influence of neuroleptic drugs and apomorphine on dopamine-sensitive adenylate cyclase of retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353338"}
{"pmid": "4353342", "title": "Hexagonal arrangement of filaments in herpes simplex virus type 2-infected cells.", "content": "Hexagonal arrangement of filaments in herpes simplex virus type 2-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353342"}
{"pmid": "4353344", "title": "Effect of angiotensin on blood pressure in normal and cirrhotic rats.", "content": "Effect of angiotensin on blood pressure in normal and cirrhotic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353344"}
{"pmid": "4353343", "title": "Pharmacological study of hydroxy bis-[2-(p-chlorophenoxy)-isobutyric acid] aluminium. II. The effect of hydroxy bis-[2-(-chlorophenoxy)-isobutyric acid] aluminum on lipid metabolism in hypercholesterolimic rats.", "content": "Pharmacological study of hydroxy bis-[2-(p-chlorophenoxy)-isobutyric acid] aluminium. II. The effect of hydroxy bis-[2-(-chlorophenoxy)-isobutyric acid] aluminum on lipid metabolism in hypercholesterolimic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353343"}
{"pmid": "4353345", "title": "Pituitary-adrenal responsiveness during lactation in rats.", "content": "Pituitary-adrenal responsiveness during lactation in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353345"}
{"pmid": "4353346", "title": "Postweaning development of negative feedback in the pituitary-adrenal system of the rat.", "content": "Postweaning development of negative feedback in the pituitary-adrenal system of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353346"}
{"pmid": "4353348", "title": "Diagnostic problems of trophoblastic disease in women aged 50 or more.", "content": "Diagnostic problems of trophoblastic disease in women aged 50 or more.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353348"}
{"pmid": "4353350", "title": "Simultaneous laparoscopy and hysteroscopy for intrauterine adhesions.", "content": "Simultaneous laparoscopy and hysteroscopy for intrauterine adhesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353350"}
{"pmid": "4353349", "title": "Ovarian lutein cysts in pregnancy.", "content": "Ovarian lutein cysts in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353349"}
{"pmid": "4353351", "title": "Pregnancy and delivery post radical hemipelvectomy.", "content": "Pregnancy and delivery post radical hemipelvectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353351"}
{"pmid": "4353352", "title": "Safety and antigenicity of temperature sensitive (TS) mutant respiratory syncytial virus (RSV) in infants and children.", "content": "Safety and antigenicity of temperature sensitive (TS) mutant respiratory syncytial virus (RSV) in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353352"}
{"pmid": "4353354", "title": "Comparative studies on the pathogenicity for mice of tumour homogenates and of nucleic acid extracted from chicken sarcomas induced by the Bryan strain of Rous sarcoma virus.", "content": "Comparative studies on the pathogenicity for mice of tumour homogenates and of nucleic acid extracted from chicken sarcomas induced by the Bryan strain of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353354"}
{"pmid": "4353355", "title": "The possibility to overcome species and age resistance in the induction of a neoplastic process by an avian tumour virus.", "content": "The possibility to overcome species and age resistance in the induction of a neoplastic process by an avian tumour virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353355"}
{"pmid": "4353356", "title": "Particularities of cytomegalovirus (CMV)-induced cytophagia.", "content": "Particularities of cytomegalovirus (CMV)-induced cytophagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353356"}
{"pmid": "4353357", "title": "Photoacoustic spectroscopy of biological materials.", "content": "Photoacoustic spectroscopy of biological materials. A new technique for performing optical spectroscopy on solids has been developed. Photoacoustic spectra of cytochrome c and hemoglobin show how this technique can be used to obtain information about optical absorptions and subsequent de-excitations in solid biological materials, particularly those which cannot readily be studied by conventional means.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353357"}
{"pmid": "4353358", "title": "Insecticide inhibition of 5alpha-dihydrotestosterone binding in the rat ventral prostate.", "content": "Insecticide inhibition of 5alpha-dihydrotestosterone binding in the rat ventral prostate. The chlorinated hydrocarbon insecticides dieldrin and o,p'-DDT inhibit binding of 5alpha-dihydrotestosterone to specific receptor proteins in rat prostate cytosol. Dieldrin is less inhibitory than o,p'-DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353358"}
{"pmid": "4353359", "title": "Murine C-type RNA virus from spontaneous neoplasms: in vitro host range and oncogenic potential.", "content": "Murine C-type RNA virus from spontaneous neoplasms: in vitro host range and oncogenic potential. Strain BALB/c mice harbor at least two host range variants of marine leukemia virus. One variant, which is host-cell tropic, is the predominant isolate from neoplastic tissues and produced lymphoreticular neoplasms when injected into BALB/c newborn mice. A second variant, whicht is isolated throughout life, grows poorly in host embryonic cells in culture and was not associated with lymphoreticular neoplasm induction when injected into newborn BALB/c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353359"}
{"pmid": "4353361", "title": "Alterations in the ontogeny and specific activity of phosphomonoesterases associated with abnormal chondrogenesis and osteogenesis in the limbs of fetuses from folic acid-deficient pregnant rats.", "content": "Alterations in the ontogeny and specific activity of phosphomonoesterases associated with abnormal chondrogenesis and osteogenesis in the limbs of fetuses from folic acid-deficient pregnant rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353361"}
{"pmid": "4353360", "title": "Human papovavirus (JC): induction of brain tumors in hamsters.", "content": "Human papovavirus (JC): induction of brain tumors in hamsters. Eighty-three percent of hamsters inoculated at birth with JC virus, a human papovavirus isolated from brain tissue of a case of progressive multifocal leukoencephalopathy, developed malignant gliomas within 6 months. Three brain tumors have been serially transplanted as subcutaneous tumors. JC virus was isolated from five of seven tumors tested. Cells from four tumors were cultivated in vitro. These cells contained an intranuclear antigen with the characteristics of a T antigen, and this antigen was antigenically related to SV40 T antigen. Although virus was not recovered from extracts of serially cultured tumor cells, JC virus was rescued when one tumor cell line was fused with permissive cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353360"}
{"pmid": "4353362", "title": "Primary pulmonary cavitating carcinomas.", "content": "Primary pulmonary cavitating carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353362"}
{"pmid": "4353364", "title": "A rapid separation of the four major deoxynucleosides and deoxyinosine by high-pressure liquid cation-exchange chromatography.", "content": "A rapid separation of the four major deoxynucleosides and deoxyinosine by high-pressure liquid cation-exchange chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353364"}
{"pmid": "4353365", "title": "Quantitation of radio-ligand binding data using a desk-top calculator in the program mode.", "content": "Quantitation of radio-ligand binding data using a desk-top calculator in the program mode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353365"}
{"pmid": "4353366", "title": "Tissue collagenase: a simplified, semiquantitative enzyme assay.", "content": "Tissue collagenase: a simplified, semiquantitative enzyme assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353366"}
{"pmid": "4353368", "title": "Micro method for determination of borohydride with NAD+.", "content": "Micro method for determination of borohydride with NAD+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353368"}
{"pmid": "4353367", "title": "A sensitive method for estimating 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.", "content": "A sensitive method for estimating 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353367"}
{"pmid": "4353369", "title": "Isolation of rat liver microsomes by gel filtration.", "content": "Isolation of rat liver microsomes by gel filtration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353369"}
{"pmid": "4353372", "title": "Characterization of neuromuscular block produced by streptomycin.", "content": "Characterization of neuromuscular block produced by streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353372"}
{"pmid": "4353373", "title": "The effect of angiotensin II and other vasoactive drugs on isolated portal vein preparations.", "content": "The effect of angiotensin II and other vasoactive drugs on isolated portal vein preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353373"}
{"pmid": "4353375", "title": "Effect of propranolol on the isolated phrenic nerve-diaphragm preparation of the rat.", "content": "Effect of propranolol on the isolated phrenic nerve-diaphragm preparation of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353375"}
{"pmid": "4353377", "title": "Alkaline ribonuclease and phosphodiesterase activity in rat liver plasma membranes.", "content": "Alkaline ribonuclease and phosphodiesterase activity in rat liver plasma membranes. The ribonuclease and phosphodiesterase activities of rat liver plasma membranes, purified from the crude nuclear fraction by centrifugation in an A-XII zonal rotor and flotation, were examined and compared. The plasma membrane is responsible for between 65 and 90% of the phosphodiesterase activity of the cell and between 25 and 30% of the particulate ribonuclease activity measured at pH8.7 in the presence of 7.5mm-MgCl(2). Both enzymes were most active between pH8.5 and 8.9. Close to the pH optimum, both enzymes were more active in Tris buffer than in Bicine or glycine buffer. Both plasma-membrane phosphodiesterase and ribonuclease were strongly activated by Mg(2+), there being at least a 12-fold difference between the activity in the presence of Mg(2+) and of EDTA. There is, however, a difference in the response of the enzymes to Mg(2+) and EDTA in that the phosphodiesterase is fully activated by 1.0mm-MgCl(2) and fully inhibited by 1.0mm-EDTA, whereas the ribonuclease requires 7.5mm-MgCl(2) for full activation and 5mm-EDTA for full inhibition. Density-gradient centrifugation has indicated that on solubilization in Triton X-100 most of the ribonuclease activity is released into a small fragment of the same size as that containing the phosphodiesterase activity. The relationship between the two activities is discussed in view of these results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353377"}
{"pmid": "4353378", "title": "Turnover of protein-bound serine phosphate in respiring slices of guinea-pig cerebral cortex. Effects of putative transmitters, tetrodotoxin and other agents.", "content": "Turnover of protein-bound serine phosphate in respiring slices of guinea-pig cerebral cortex. Effects of putative transmitters, tetrodotoxin and other agents. 1. The effect of various agents on the turnover of protein-bound phosphorus in respiring slices of cerebral cortex was studied. 2. Confirming previous work turnover was increased by the application of electrical pulses for 10s to the tissue. 3. Turnover was also increased by exposure of the slices for 10min to noradrenaline (0.5mm), 5-hydroxytryptamine (1mum) and histamine (0.1mm). 4. When slices were stimulated by electrical pulses in the presence of histamine the increase in turnover was the sum of the responses given by each agent above, suggesting that different phosphorylating systems were involved. 5. Tetrodotoxin (0.5mum) blocked the increased turnover due to electrical pulses, but not that due to histamine. Tetrodotoxin also prevented the increase in tissue cyclic AMP content caused by the application of electrical pulses. 6. Phosphoprotein turnover was not affected by adenosine, despite the increase in tissue cyclic AMP content given by this agent. 7. Adenosine blocked the phosphoprotein response to histamine, but did not affect the response to electrical pulses. 8. The results are discussed in relation to the hypothesis that the stimulation of protein phosphorus turnover by electrical pulses is secondary to the release of cyclic AMP in the tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353378"}
{"pmid": "4353379", "title": "Protein kinase activity in membrane preparations from ox brain. Stimulation of intrinsic activity by adenosine 3':5'-cyclic monophosphate.", "content": "Protein kinase activity in membrane preparations from ox brain. Stimulation of intrinsic activity by adenosine 3':5'-cyclic monophosphate. 1. Properties of the stimulation by cyclic AMP of the intrinsic protein kinase activity of membrane fragments from ox brain were studied. 2. Stimulation of activity declined from about 100% at 1min to less than 20% at 10min. The time-course was explained by the observation that cyclic AMP did not stimulate turnover of protein-bound serine phosphate once the membrane protein was fully phosphorylated. 3. Cyclic AMP accelerated the activity of a component of the basal activity rather than activating a different kinase. 4. The pH optimum for both the stimulated and basal activities was 7.2-7.4. NaCl (100mm) and KCl (10-100mm) inhibited the stimulated activity but did not affect the basal activity. 5. Strychnine and theophylline inhibited both activites equally, but the stimulated activity was more sensitive to inhibition by adenosine, bicuculline, vinblastin, veratrine, N-ethylmaleimide and cysteine. 6. No firm evidence for a role for endogenous cyclic AMP in the basal activity was found, but the possibility was not excluded. 7. Some 90% of both the stimulated and basal activities remained in an insoluble form after treatment of the membrane fragments with Triton X-100 (0.5%).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353379"}
{"pmid": "4353380", "title": "The heterogeneous distribution of acid hydrolases within a homogeneous population of cultured mammalian cells.", "content": "The heterogeneous distribution of acid hydrolases within a homogeneous population of cultured mammalian cells. 1. Chinese-hamster ovary fibroblasts were cultured to provide a homogeneous cell population. Homogenates obtained from these cells were fractionated by centrifugation techniques and the resulting fractions were analysed for protein and for enzymes representative of certain subcellular particles. 2. Unlike those in rat liver homogenates, the mitochondrial and lysosomal populations proved impossible to separate by differential centrifugation owing to the similarity of their sedimentation properties. Their resolution was possible by using isopycnic centrifugation in a continuous sucrose density gradient. 3. The mitochondrial population equilibrated at a density of 1.17g.cm(-3) as in rat liver homogenates. However, the lysosomal population equilibrated at a lower rather than a higher density position than the mitochondria and the probable reasons for this are discussed. 4. The lysosomal population subdivided into two groups characterized by differences in acid hydrolase content and equilibrium densities. The fraction with a density of 1.15g.cm(-3) contained the majority of arylsulphatases A and B, of cathepsin and of beta-acetylglucosaminidase activities, whereas that with a density of 1.09g.cm(-3) contained the majority of the acid phosphatase and acid ribonuclease activities. The probable division of the lysosomal population of a single cell into a number of distinguishable subgroups is suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353380"}
{"pmid": "4353381", "title": "The effects of calcium ions on the activities of trehalase, hexokinase, phosphofructokinase, fructose diphosphatase and pyruvate kinase from various muscles.", "content": "The effects of calcium ions on the activities of trehalase, hexokinase, phosphofructokinase, fructose diphosphatase and pyruvate kinase from various muscles. 1. The effects of Ca(2+) on the activities and regulatory properties of trehalase, hexokinase, phosphofructokinase, fructose diphosphatase and pyruvate kinase from vertebrate red and white muscle and insect fibrillar and non-fibrillar muscle have been investigated. These muscles were selected because of the possible difference in the role of glycolysis in energy production in the vertebrate muscles, and the possible difference in the role of Ca(2+) in the control of contraction in the two types of insect muscle. An increase in Ca(2+) concentration from 0.001mum to 10mum did not modify the activities nor did it modify the regulatory properties of these enzymes from these various muscles. 2. Concentrations of Ca(2+) above 0.1mm inhibited the activities of hexokinase and phosphofructokinase from the different muscles. It has been suggested that this inhibition may provide the basis for a theory of regulation of glycolysis (Margreth et al., 1967). If phosphofructokinase is located within the sarcoplasmic reticulum, its activity will be inhibited when the muscle is at rest, but the release of Ca(2+) from the reticulum during contraction will lead to a stimulation of its activity and hence an increase in glycolytic flux. The distribution of hexokinase and phosphofructokinase in the various cell fractions of these muscles was very variable. In particular, both enzymes were present almost exclusively in the 100000g supernatant fraction in the extracts of insect flight muscles. Thus there is no correlation between the properties of the enzymes and their distribution in muscle. 3. It is concluded that Ca(2+) does not control the activities of the important regulatory enzymes of glycolysis in muscle. It is suggested that in some muscles the sensitivity of the control mechanism at the level of phosphofructokinase to changes in the concentration of AMP may be increased by a process known as ;substrate-cycling'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353381"}
{"pmid": "4353383", "title": "Changes in enzyme activities and distributions during glucose de-repression and respiratory adaptation of anaerobically grown Saccharomyces carlsbergensis.", "content": "Changes in enzyme activities and distributions during glucose de-repression and respiratory adaptation of anaerobically grown Saccharomyces carlsbergensis. 1. During anaerobic glucose de-repression the respiration rate of whole cells of Saccharomyces carlsbergensis remained constant and was insensitive to antimycin A but was inhibited by 30% by KCN. Aeration of cells for 1 h led to increased respiration rate which was inhibited by 80% by antimycin A or KCN. 2. Homogenates were prepared from sphaeroplasts of anaerobically grown, glucose de-repressed cells and the distribution of marker enzymes was investigated after zonal centrifugation on sucrose gradients containing MgCl(2). These homogenates contained no detectable cytochrome c oxidase or catalase activity. The complex density distributions of NADH- and NADPH-cytochrome c oxidoreductases and adenosine triphosphatase(s) [ATPase(s)] were very different from those of anaerobically grown, glucose-repressed cells. 3. The specific activity of total ATPase was lowered and sensitivity to oligomycin decreased from 58 to 7% during de-repression. 4. Cytochrome c oxidase and catalase activities were detectable in homogenates of cells after 10min aeration. Zonal centrifugation indicated complex, broad sedimentable distributions of all enzyme activities assayed; the peaks of activity were at 1.27g/ml. 5. Centrifugation of homogenates of cells adapted for 30min and 3 h indicated a shift of density of the major sedimentable peak from 1.25g/ml (30min) to 1.235g/ml (3 h). After 30min adaptation a minor zone of oligomycin-sensitive ATPase and 15% of the total cytochrome c oxidase activities were detected at rho=1.12g/l; these particles together with those of higher density containing cytochrome c oxidase, ATPase and NADH-cytochrome c oxidoreductase activities were all sedimented at 10(5)g-min. 6. Electron microscopy indicated that the mitochondria-like structures of anaerobically grown, glucose-de-repressed cells were similar to those of repressed cells. After 10min of respiratory adaptation highly organized mitochondria were evident which resembled the condensed forms of mitochondria of aerobically grown, glucose-de-repressed cells. High-density zonal fractions of homogenates of cells after adaptation also contained numerous electron-dense vesicles 0.05-0.2mum in diameter. 7. The possibility that the ;promitochondria' of anaerobically grown cells may not be the direct structural precursors of fully functional mitochondria is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353383"}
{"pmid": "4353382", "title": "Developmental changes in microheterogeneity of foetal plasma glycoproteins of mice.", "content": "Developmental changes in microheterogeneity of foetal plasma glycoproteins of mice. Changes in microheterogeneity of foetal plasma glycoproteins during development of mouse embryos were investigated. Analysis of foetal plasma by polyacrylamide-gel electrophoresis indicated three major zones of proteins: (1) transferrins, (2) alpha-foetoproteins and (3) albumin. Three transferrins (Tr1, Tr2, Tr3) and five alpha-foetoproteins (Fp1, Fp2, Fp3, Fp4, Fp5) were resolved. Evidence for the presence of transferrins was the binding of (59)Fe to the three electrophoretic variants. By day 15.5 of gestation, there was a marked increase in the more-acidic components (Tr3, Fp4, Fp5) and a decrease in the less-acidic ones (Tr1, Tr2, Fp1, Fp2, Fp3). Treatment of foetal plasma with neuraminidase at this time of development converted the more acidic components into Tr1 and Tr2 and Fp1, Fp2 and Fp3. Furthermore, it was shown that early in development (day 12.5) only the less-acidic components of transferrin and alpha-foetoprotein were synthesized; at the later time in development (day 14.5) new synthesis of the acidic components of both groups occurred. That these more-acidic components of alpha-foetoprotein (Fp4, Fp5) were in fact electrophoretic variants of the less-acidic alpha-foetoproteins was shown by the immunoprecipitation of labelled Fp4 and Fp5 with anti-Fp1, anti-Fp2 and anti-Fp3. From these results it is postulated that the plasma glycoproteins that are synthesized later in development contain increased amounts of sialic acid and that the observed changes in microheterogeneity of these proteins represent regulation of glycoprotein biosynthesis at the level of carbohydrate attachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353382"}
{"pmid": "4353385", "title": "Pencillin amidase production by Bacillus megaterium.", "content": "Pencillin amidase production by Bacillus megaterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353385"}
{"pmid": "4353384", "title": "Phosphorylation of high-molecular-weight membrane protein species in Chinese-hamster ovary cells in culture: effect of 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate plus testosterone.", "content": "Phosphorylation of high-molecular-weight membrane protein species in Chinese-hamster ovary cells in culture: effect of 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate plus testosterone. Growth of Chinese-hamster ovary cells in [(32)P]phosphate and [(3)H]leucine and subsequent assay of the plasma membranes reveals phosphorylation in two protein regions corresponding to molecular weights of 280000 and 195000. Culture in the presence of the 6-N,2-O'-dibutyryl derivative of cyclic AMP plus testosterone does not stimulate [(32)P]-phosphate incorporation, but determines a modification in the qualitative pattern of phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353384"}
{"pmid": "4353386", "title": "Phospholipase-C from Bacillus cereus: production, purification, and properties.", "content": "Phospholipase-C from Bacillus cereus: production, purification, and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353386"}
{"pmid": "4353387", "title": "Detection of circulating hepatoma D23 antigen and immune complexes in tumour bearer serum.", "content": "Detection of circulating hepatoma D23 antigen and immune complexes in tumour bearer serum. Serum from rats bearing progressively growing aminoazo dye-induced rat hepatomata has been fractionated by Sephadex G150 gel filtration chromatography and isolated fractions have been examined by indirect membrane immunofluorescence techniques to detect tumour specific antigen and antibody. Hepatoma D23-specific antigenic activity was associated with material (of approximate molecular weight <150,000) isolated in the included volume of the gel at pH 7·3. The fraction excluded from the gel (of approximate molecular weight >150,000) was adjusted to pH 3·0 and further separated by Sephadex G150 gel filtration chromatography at pH 3·0 into gel included and excluded fractions. Hepatoma D23 specific antibody, demonstrable by membrane immunofluorescence staining of hepatoma D23 cells, was found to be eluted in the excluded volume and specific antigenic activity was retarded into the included volume of the gel. These results indicate that hepatoma D23 bearer serum contains free circulating tumour specific antigen in excess, together with specific immune complexes. The presence of these factors in tumour bearer serum is discussed in terms of \"blocking\" phenomena whereby serum factors may protect tumour cells from sensitized lymphocyte cytotoxic attack.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353387"}
{"pmid": "4353390", "title": "Mammary tumour and hepatoma suppression by dietary restriction in C3H Avy mice.", "content": "Mammary tumour and hepatoma suppression by dietary restriction in C3H Avy mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353390"}
{"pmid": "4353388", "title": "A new model for inducing malignant ovarian tumours in rats.", "content": "A new model for inducing malignant ovarian tumours in rats. After the implantation of ovarian tissue into the spleen of gonadectomized female Sprague-Dawley rats (splenic ovary), luteomata and later benign granulosa or granulosa-theca cell tumours develop. Treatment of these rats with 7,12 dimethylbenz(a)anthracene (DMBA), given intravenously, 2 mg/kg body weight weekly, total dosage 40 mg/kg, immediately and especially 25 weeks after implantation of ovarian tissue into the spleen, led to malignant, partially metastasizing granulosa, and in one case theca cell tumours, 16-46 weeks after beginning the carcinogen treatment. No malignant neoplastic growth was seen when diethylnitrosamine (DEN), 20 mg/kg once weekly for life, was injected subcutaneously immediately or 25 weeks after implanting ovarian tissue.Since the normal, non-implanted rat ovary was not affected by DMBA treatment the malignant transformation of splenic ovaries in the respective experimental groups may be related to the increased stimulation by pituitary gonadotrophins and formation of luteomata or beginning granulosa and theca cell proliferations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353388"}
{"pmid": "4353389", "title": "Enzyme activated alkylating agents.", "content": "Enzyme activated alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353389"}
{"pmid": "4353391", "title": "Possible viral aetiology of human breast cancer.", "content": "Possible viral aetiology of human breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353391"}
{"pmid": "4353393", "title": "Cyclic AMP and adenyl cyclase in the developing rat brain.", "content": "Cyclic AMP and adenyl cyclase in the developing rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353393"}
{"pmid": "4353396", "title": "Two types of response patterns from cat retinal ganglion cells to moving stimuli.", "content": "Two types of response patterns from cat retinal ganglion cells to moving stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353396"}
{"pmid": "4353397", "title": "Cyclic 3',5'-adenosine monophosphate in Tetrahymena pyriformis.", "content": "Cyclic 3',5'-adenosine monophosphate in Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353397"}
{"pmid": "4353398", "title": "The effect of semicarbazide pretreatment on the depressant action of barbiturates.", "content": "The effect of semicarbazide pretreatment on the depressant action of barbiturates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353398"}
{"pmid": "4353399", "title": "Toxicity of polychlorinated biphenyls increased with simultaneous ingestion of alkylbenzene sulfonic acid salt.", "content": "Toxicity of polychlorinated biphenyls increased with simultaneous ingestion of alkylbenzene sulfonic acid salt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353399"}
{"pmid": "4353400", "title": "In vitro corticosteroidogenesis by the adrenal gland of the chicken (Gallus domesticus).", "content": "In vitro corticosteroidogenesis by the adrenal gland of the chicken (Gallus domesticus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353400"}
{"pmid": "4353392", "title": "A comparison of dream content in laboratory dream reports of schizophrenic and depressive patient groups.", "content": "A comparison of dream content in laboratory dream reports of schizophrenic and depressive patient groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353392"}
{"pmid": "4353404", "title": "A psychophysiological study of nightmares and night terrors. I. Physiological aspects of the stage 4 night terror.", "content": "A psychophysiological study of nightmares and night terrors. I. Physiological aspects of the stage 4 night terror.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353404"}
{"pmid": "4353405", "title": "Five classes of visual interneurons in the optic nerve of the hermit crab.", "content": "Five classes of visual interneurons in the optic nerve of the hermit crab.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353405"}
{"pmid": "4353406", "title": "Restorative effects of cyclic AMP on complex bioelectric activities of cultured fetal rodent CNS tissues after acute CA++ deprivation.", "content": "Restorative effects of cyclic AMP on complex bioelectric activities of cultured fetal rodent CNS tissues after acute CA++ deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353406"}
{"pmid": "4353407", "title": "Chemosensitivity of mouse neuroblastoma cells in vitro.", "content": "Chemosensitivity of mouse neuroblastoma cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353407"}
{"pmid": "4353408", "title": "Melanotic medulloblastoma of the cerebellum.", "content": "Melanotic medulloblastoma of the cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353408"}
{"pmid": "4353410", "title": "How is the H-reflex modulated during rapid eye movement (REM) sleep?", "content": "How is the H-reflex modulated during rapid eye movement (REM) sleep?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353410"}
{"pmid": "4353411", "title": "Studies on bovine para-influenza (type-3) virus.", "content": "Studies on bovine para-influenza (type-3) virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353411"}
{"pmid": "4353409", "title": "Determination of the frequency response of isometric soleus muscle in the cat using random nerve stimulation.", "content": "Determination of the frequency response of isometric soleus muscle in the cat using random nerve stimulation. 1. The frequency response of isometric soleus muscle was determined efficiently by analysis of the unfused tension generated during short periods of random stimulation of the divided ventral roots, in anaesthetized cats.2. Despite the complexities of skeletal muscle, the frequency response of soleus, at moderate lengths and stimulation rates in the physiological range, is closely approximated by the frequency response function for a simple, linear, second-order system near critical damping.3. The soleus muscle shows a uniformly high sensitivity to fluctuations in nerve activity over a range of frequencies similar to the range of frequencies of muscular activity observable during behaviour. The nerve-muscle preparation appears to be well suited for smooth and steady motor activity, since it is much less responsive to the higher frequency components contained in individual action potentials or generated in tremor.4. The second-order parameters: low-frequency gain, natural frequency and damping ratio provide useful descriptions of the changes in the muscle's response caused by variations of muscle length, nerve stimulation rate or number of active motor units.5. A reduction in tension incurred, for example, during fatigue can be compensated to some extent either by a lengthening of the loaded muscle or through an increase in neural spike repetition rate. However, both mechanisms produce concomitant increases in the ;sluggishness' (increased damping and lower natural frequency) of the preparation. This sluggishness may arise out of limitations imposed by the mechanism for the re-uptake of calcium into the sarcotubular system.6. One naturally occurring method of increasing tension, by recruitment of more active motoneurones, seems to be desirable because tension can be augmented in this way without an increase in sluggishness. This is presumably because recruitment increases the muscle's response without affecting excitation-contraction coupling in fibres already active.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353409"}
{"pmid": "4353412", "title": "Superinfection of simian virus 40 transformed human cells with human adenovirus.", "content": "Superinfection of simian virus 40 transformed human cells with human adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353412"}
{"pmid": "4353403", "title": "Determining the biological age of the preschool child from a hand-wrist radiograph.", "content": "Determining the biological age of the preschool child from a hand-wrist radiograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353403"}
{"pmid": "4353413", "title": "Characteristic behaviour of the cocultures of the SV40 transformed rabbit kidney cells and African green monkey kidney cells.", "content": "Characteristic behaviour of the cocultures of the SV40 transformed rabbit kidney cells and African green monkey kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353413"}
{"pmid": "4353402", "title": "Experimental studies of peribronchography.", "content": "Experimental studies of peribronchography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353402"}
{"pmid": "4353415", "title": "Glomerulonephritis associated with immune complex deposits and viral particles in spontaneous murine leukemia. An electron microscopic study with immunofluorescence.", "content": "Glomerulonephritis associated with immune complex deposits and viral particles in spontaneous murine leukemia. An electron microscopic study with immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353415"}
{"pmid": "4353416", "title": "Ultrastructure of parathyroid glands and plasma immunoreactive parathyroid hormone in pregnant cows fed normal and high calcium diets.", "content": "Ultrastructure of parathyroid glands and plasma immunoreactive parathyroid hormone in pregnant cows fed normal and high calcium diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353416"}
{"pmid": "4353417", "title": "Sulfaguanidine protection of mouse liver from carbon tetrachloride-induced necrosis.", "content": "Sulfaguanidine protection of mouse liver from carbon tetrachloride-induced necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353417"}
{"pmid": "4353418", "title": "The effect of vincristine on the calcium transport and phospholipid composition of rat skeletal muscle microsomes.", "content": "The effect of vincristine on the calcium transport and phospholipid composition of rat skeletal muscle microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353418"}
{"pmid": "4353419", "title": "Ultrastructural study of cytochrome oxidase in oncocytoma.", "content": "Ultrastructural study of cytochrome oxidase in oncocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353419"}
{"pmid": "4353420", "title": "Polypeptide specific for cells with adenovirus 2-SV40 hybrid Ad2+ND1.", "content": "Polypeptide specific for cells with adenovirus 2-SV40 hybrid Ad2+ND1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353420"}
{"pmid": "4353421", "title": "Altered metabolism and endogenous cyclic AMP in cultured cells deficient in cyclic AMP-binding proteins.", "content": "Altered metabolism and endogenous cyclic AMP in cultured cells deficient in cyclic AMP-binding proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353421"}
{"pmid": "4353422", "title": "Identification of two distinct species of procollagen synthesized by a clonal line of calf dermatosparactic cells.", "content": "Identification of two distinct species of procollagen synthesized by a clonal line of calf dermatosparactic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353422"}
{"pmid": "4353423", "title": "Localization of rat liver alpha-foetoprotein by cell affinity labelling with tritiated oestrogens.", "content": "Localization of rat liver alpha-foetoprotein by cell affinity labelling with tritiated oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353423"}
{"pmid": "4353425", "title": "Tumor lipids.", "content": "Tumor lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353425"}
{"pmid": "4353427", "title": "Cyclic 3',5'-adenosine monophosphate in the rat gastric mucosa after starvation, feeding, and pentagastrin.", "content": "Cyclic 3',5'-adenosine monophosphate in the rat gastric mucosa after starvation, feeding, and pentagastrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353427"}
{"pmid": "4353428", "title": "MHPG excretion in depressive disorders: relation to clinical subtypes and desynchronized sleep.", "content": "MHPG excretion in depressive disorders: relation to clinical subtypes and desynchronized sleep. The urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) was significantly lower in patients with manic-depressive depressions than in patients with chronic characterological depressions. There was an inverse relationship between MHPG excretion and the amount of time spent in desynchronized sleep, particularly in the manic-depressive disorders. Excretion of MHPG was not related to the degree of retardation, agitation, or anxiety in these patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353428"}
{"pmid": "4353429", "title": "Intracellular receptors for 5alpha-dihydrostestosterone in the epididymis of adult rats. Comparison with the androgenic receptors in the ventral prostate and the androgen binding protein (ABP) in the testicular and epididymal fluid.", "content": "Intracellular receptors for 5alpha-dihydrostestosterone in the epididymis of adult rats. Comparison with the androgenic receptors in the ventral prostate and the androgen binding protein (ABP) in the testicular and epididymal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353429"}
{"pmid": "4353430", "title": "The metabolism of estriol in rabbits.", "content": "The metabolism of estriol in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353430"}
{"pmid": "4353431", "title": "Retro-steroids. I. Metabolism of the progestogen 6-chloro-9 , 10 -pregna-1,4,6-triene-3,20-dione in man.", "content": "Retro-steroids. I. Metabolism of the progestogen 6-chloro-9 , 10 -pregna-1,4,6-triene-3,20-dione in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353431"}
{"pmid": "4353432", "title": "Progesterone binding in the immature mouse and rat uterus.", "content": "Progesterone binding in the immature mouse and rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353432"}
{"pmid": "4353433", "title": "Primary brain tumors: tumor immunity and immunocompetence.", "content": "Primary brain tumors: tumor immunity and immunocompetence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353433"}
{"pmid": "4353434", "title": "Granular cell myoblastomas of the pituitary region.", "content": "Granular cell myoblastomas of the pituitary region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353434"}
{"pmid": "4353424", "title": "Serological evidence for CELO virus infection in chickens and turkeys in Denmark.", "content": "Serological evidence for CELO virus infection in chickens and turkeys in Denmark.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353424"}
{"pmid": "4353435", "title": "Study of Japanese encephalitis virus in Chiangmai Valley, Thailand. I. Introduction and study design.", "content": "Study of Japanese encephalitis virus in Chiangmai Valley, Thailand. I. Introduction and study design.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353435"}
{"pmid": "4353436", "title": "Study of Japanese encephalitis virus in Chiangmai valley, Thailand. II. Human clinical infections.", "content": "Study of Japanese encephalitis virus in Chiangmai valley, Thailand. II. Human clinical infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353436"}
{"pmid": "4353437", "title": "Study of Japanese encephalitis virus in Chiangmai Valley, Thailand. 3. Human seroepidemiology and inapparent infections.", "content": "Study of Japanese encephalitis virus in Chiangmai Valley, Thailand. 3. Human seroepidemiology and inapparent infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353437"}
{"pmid": "4353438", "title": "Epidemiology of sudden infant death syndrome and lower respiratory tract disease in young children: a comparison.", "content": "Epidemiology of sudden infant death syndrome and lower respiratory tract disease in young children: a comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353438"}
{"pmid": "4353439", "title": "Epidemiology of respiratory syncytial virus infection among infants and children in Chicago.", "content": "Epidemiology of respiratory syncytial virus infection among infants and children in Chicago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353439"}
{"pmid": "4353440", "title": "The therapeutic tumult and the ophthalmologist. 35th De Schweinitz lecture.", "content": "The therapeutic tumult and the ophthalmologist. 35th De Schweinitz lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353440"}
{"pmid": "4353441", "title": "The effect of ophthalmic ointments on corneal wound healing.", "content": "The effect of ophthalmic ointments on corneal wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353441"}
{"pmid": "4353442", "title": "Cyclomegalovirus retinitis.", "content": "Cyclomegalovirus retinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353442"}
{"pmid": "4353444", "title": "Isolation and characterization of a rough microsomal fraction from rat kidney that is enriched in lysosomal enzymes.", "content": "Isolation and characterization of a rough microsomal fraction from rat kidney that is enriched in lysosomal enzymes. 1. A special population of rough microsomal material (microsomes) rich in lysosomal acid hydrolases was separated by isopycnic centrifugation as a discrete fraction (RM(2)) from the bulk of rough microsomal material in rat kidney because of its greater density. 2. The specific activities of five acid hydrolases in the RM(2) fraction were approximately one-half those of a purified lysosomal (L) fraction and 10- to 30-fold greater than those of an ordinary rough microsomal (RM(1)) fraction. 3. These special rough microsomes have a distinctive ultrastructure and electron-cytochemical properties. Their cisternal content resembles the matrix of lysosomes in that it is electron-dense, osmiophilic and plumbophilic and gives a positive reaction for acid phosphatase activity. 4. Polyacrylamide-gel electrophoresis of soluble proteins from the L fraction resolved nine anionic glycoproteins, most of which exhibit acid hydrolase activities (Goldstone & Koenig, 1970, 1973; Goldstone et al., 1971a). The most anionic glycoprotein is the acidic lipoglycoprotein of the lysosomal matrix (Goldstone et al., 1970). 5. Polyacrylamide-gel electrophoresis of soluble proteins from the RM(2) fraction resolved two cationic glycoproteins with acid hydrolase activities (Goldstone & Koenig, 1973) and an anionic glycoprotein with the same electrophoretic mobility as the lysosomal lipoglycoprotein, but without its lipid constituents or capacity to bind the basic fluorochrome Acridine Orange. These constituents are considered to be the precursors of the lysosomal glycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353444"}
{"pmid": "4353443", "title": "Studies of nuclei separated by zonal centrifugation from liver of rats treated with thioacetamide.", "content": "Studies of nuclei separated by zonal centrifugation from liver of rats treated with thioacetamide. 1. The effects of the inclusion of thioacetamide in the diet on the properties of rat liver nuclei were studied both in adolescent rats, in which the parenchymal cells contain diploid nuclei, and in young adult rats, with a high proportion of tetraploid nuclei. 2. These investigations included a survey of the sedimentation properties of the nuclei, the nuclear volumes, content of DNA, RNA and protein, the incorporation in vivo of [(3)H]thymidine into DNA and [(14)C]orotate into RNA, and measurements of the activity of RNA polymerase and ribonuclease. These studies were conducted on nuclei fractionated by zonal centrifugation. 3. In both groups of animals, exposure to thioacetamide produced large numbers of nuclei that were abnormal in their chemical composition and enzymic activity. The changes were complex as regards both the types of nuclei that were affected and in their variation with time. 4. In adolescent rats two waves of synthesis of DNA and RNA were observed, one at 3 days and the other after 2 weeks of treatment. The first decline in the incorporations into both DNA and RNA coincided with a decrease in the pool sizes of some of the precursors. The activity of RNA polymerase was not substantially altered. A marked increase in the content of protein was observed before the first wave of synthesis. The normal progressive increase in tetraploid nuclei was prevented. 5. In young adult rats two waves of DNA synthesis were detected. Each was preceded by a large increase in the amount of protein per nucleus but was not accompanied by increased RNA synthesis. After 4 weeks of treatment, the diploid stromal nuclei appeared mainly unaffected and large numbers of tetraploid nuclei with a greatly increased quantity of protein were observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353443"}
{"pmid": "4353445", "title": "Adrenal microsomal C19-steroid 5alpha-reductase activity in the Snell transplantable rat adrenocortical tumour 494 and the effect of oestradiol, testosterone propionate and adrenocorticotrophin in intact and gonadectomized rats.", "content": "Adrenal microsomal C19-steroid 5alpha-reductase activity in the Snell transplantable rat adrenocortical tumour 494 and the effect of oestradiol, testosterone propionate and adrenocorticotrophin in intact and gonadectomized rats. The C(19)-steroid 5alpha-reductase activity in the microsomal fraction of rat adrenal tissue under various hormonal treatments was examined. In intact control rats the activity is similar in both males and females, and after gonadectomy it is markedly increased. Treatment with oestradiol (150mug/day per animal for 7 days) or testosterone propionate (2mg/day per animal for 7 days) lowered the activity of 5alpha-reductase in castrated animals to approximately the values for intact animals in both sexes, and in intact animals the activity was also decreased by these treatments. The enzyme activity was also decreased by adrenocorticotrophin treatment but to a lesser extent than by the steroid hormones. The activity of the 5alpha-reductase enzyme in the Snell adrenocortical tumour 494 is very low when incubated as a whole homogenate, but the activity in microsomal material of the tumour was measured and unexpectedly found to be similar to that in intact controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353445"}
{"pmid": "4353446", "title": "Control of ovarian cholesterol ester biosynthesis.", "content": "Control of ovarian cholesterol ester biosynthesis. 1. Experimental evidence is presented for a role of progesterone and 20alpha-hydroxypregn-4-en-3-one as inhibitors of cholesterol ester synthetase in the acute depletion of ovarian cholesterol ester after trophic stimulation. 2. Luteinizing hormone in vitro decreased by 84% the rate of esterification of cholesterol with added [(14)C]oleate by slices of rabbit ovarian interstitial tissue; this effect was mimicked by cyclic AMP (adenosine 3':5'-cyclic monophosphate) in vitro, and occurred without large changes in precursor pool sizes or membrane permeability. 3. Cyclic AMP was shown to have no direct effect on cholesterol ester synthetase or cholesterol esterase in cell-free extracts of rabbit ovarian interstitial tissue, but decreased the activity of cholesterol ester synthetase (not that of cholesterol esterase) in extracts prepared from slices previously incubated with it. 4. The inhibitory effect of cyclic AMP on esterification of cholesterol with added [(14)C]-oleate was prevented by both cycloheximide and aminoglutethimide phosphate (which also inhibited steroid synthesis in response to cyclic AMP). 5. Cyclic AMP raised the intracellular concentrations of progesterone and 20alpha-hydroxypregn-4-en-3-one in incubated slices by factors of 2.8 and 3.9 respectively. 6. Cycloheximide and aminoglutethimide phosphate administered in vivo blocked cholesterol ester depletion in response to luteinizing hormone in rats; in these ovaries cycloheximide and aminoglutethimide phosphate decreased the concentrations of progesterone and 20alpha-hydroxypregn-4-en-3-one and luteinizing hormone raised them. 7. Progesterone and 20alpha-hydroxypregn-4-en-3-one added to cell-free extracts of rabbit ovarian interstitial tissue in vitro (at concentrations comparable with those found in incubated slices) inhibited cholesterol ester synthetase by up to 85%. 8. The results are discussed with reference to the acute control of cholesterol ester concentrations in the ovary and adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353446"}
{"pmid": "4353447", "title": "Hepatic lipid droplets. Isolation, morphology and composition.", "content": "Hepatic lipid droplets. Isolation, morphology and composition. The floating lipid layer isolated centrifugation of rat liver was examined for composition and ultrastructure. It was chiefly composed of triglycerides and cholesterol esters plus much smaller amounts of free cholesterol, diglycerides, phospholipid and protein. No free fatty acids were detected. The triglyceride and cholesterol ester fractions consisted mostly of esters of linoleic acid, oleic acid and palmitic acid. Electron micrographs of the floating lipid layer revealed numerous spherical osmiophilic droplets having a mean diameter of 0.5-2mum with a very-thin dense outer coat. Similar structures were observed as organelles in electron micrographs of the intact liver cell. The amount of triglyceride in the layer decreased in rats starved for 72h, but pellet triglyceride (homogenate minus the floating lipid layer) was unchanged. These results suggest that the floating lipid layer is the representative in vitro of lipid-rich organelles which probably function as a depot form of hepatic-cell neutral lipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353447"}
{"pmid": "4353450", "title": "The effects of selective interruption and deprivation of sleep in the human newborn.", "content": "The effects of selective interruption and deprivation of sleep in the human newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353450"}
{"pmid": "4353451", "title": "Hypothyroidism and the maturation of the hypothalamo-hypophyseal-adrenal axis.", "content": "Hypothyroidism and the maturation of the hypothalamo-hypophyseal-adrenal axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353451"}
{"pmid": "4353452", "title": "The effect of phentolamine on adenylate cyclase and on isoproterenol stimulation in leukocytes from asthmatic and nonasthmatic subjects.", "content": "The effect of phentolamine on adenylate cyclase and on isoproterenol stimulation in leukocytes from asthmatic and nonasthmatic subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353452"}
{"pmid": "4353453", "title": "An epizootic of malignant catarrhal fever in feedlot cattle.", "content": "An epizootic of malignant catarrhal fever in feedlot cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353453"}
{"pmid": "4353454", "title": "Evidence of bovine C-type (leukemia) virus in dairy cattle.", "content": "Evidence of bovine C-type (leukemia) virus in dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353454"}
{"pmid": "4353455", "title": "Incidence of Clostridium perfringens in dehydrated soup, gravy, and spaghetti mixes.", "content": "Incidence of Clostridium perfringens in dehydrated soup, gravy, and spaghetti mixes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353455"}
{"pmid": "4353457", "title": "Renal hamartomas and nephroblastomatosis with fetal gigantism: a familial syndrome.", "content": "Renal hamartomas and nephroblastomatosis with fetal gigantism: a familial syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353457"}
{"pmid": "4353458", "title": "Varicella reactivation in nephrotic syndrome treated with cyclophosphamide and adrenal corticosteroids.", "content": "Varicella reactivation in nephrotic syndrome treated with cyclophosphamide and adrenal corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353458"}
{"pmid": "4353459", "title": "Complete analysis of levodopa capsules and tablets by GLC.", "content": "Complete analysis of levodopa capsules and tablets by GLC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353459"}
{"pmid": "4353461", "title": "Peripheral neuropathy secondary to isoniazid-induced pyridoxine deficiency.", "content": "Peripheral neuropathy secondary to isoniazid-induced pyridoxine deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353461"}
{"pmid": "4353463", "title": "Some clinical aspects of non traumatic mechanical lesions of peripheral nerves. Analysis of 3465 personal cases.", "content": "Some clinical aspects of non traumatic mechanical lesions of peripheral nerves. Analysis of 3465 personal cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353463"}
{"pmid": "4353465", "title": "Attempts to propagate human tumor explants in mice inoculated with human thymus antiserum.", "content": "Attempts to propagate human tumor explants in mice inoculated with human thymus antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353465"}
{"pmid": "4353466", "title": "An examination of two bovine respiratory disease vaccines.", "content": "An examination of two bovine respiratory disease vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353466"}
{"pmid": "4353464", "title": "Carbohydrate metabolism in the rat uterus during early pregnancy.", "content": "Carbohydrate metabolism in the rat uterus during early pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353464"}
{"pmid": "4353467", "title": "Modification of metabolic effects of ethanol by fructose.", "content": "Modification of metabolic effects of ethanol by fructose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353467"}
{"pmid": "4353469", "title": "Spectroscopic methods in biology, with application to neurophysiology.", "content": "Spectroscopic methods in biology, with application to neurophysiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353469"}
{"pmid": "4353468", "title": "Metabolism of fructose in liver.", "content": "Metabolism of fructose in liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353468"}
{"pmid": "4353471", "title": "Compressive behaviour of a physiological tissue.", "content": "Compressive behaviour of a physiological tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353471"}
{"pmid": "4353475", "title": "Filamentous forms of enveloped A particles in cell cultures from chemically induced rat hepatomas.", "content": "Filamentous forms of enveloped A particles in cell cultures from chemically induced rat hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353475"}
{"pmid": "4353474", "title": "The effects of protein on lipid organization in a model membrane system: a spin probe and x-ray study.", "content": "The effects of protein on lipid organization in a model membrane system: a spin probe and x-ray study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353474"}
{"pmid": "4353476", "title": "3-(Tetraacetyl glucopyranos-2-yl)-1-(2-chloroethyl)-1-nitrosourea, an antitumor agent with modified bone marrow toxicity.", "content": "3-(Tetraacetyl glucopyranos-2-yl)-1-(2-chloroethyl)-1-nitrosourea, an antitumor agent with modified bone marrow toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353476"}
{"pmid": "4353477", "title": "Enzymatic and immunological studies on pyruvate carboxylase in livers and liver tumors.", "content": "Enzymatic and immunological studies on pyruvate carboxylase in livers and liver tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353477"}
{"pmid": "4353478", "title": "Studies on certain cytoplasmic enzymes and specific estrogen receptors in human breast cancer and in nonmalignant diseases of the breast.", "content": "Studies on certain cytoplasmic enzymes and specific estrogen receptors in human breast cancer and in nonmalignant diseases of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353478"}
{"pmid": "4353480", "title": "Inhibition by N6, O2'-dibutyryl 3',5'-cyclic adenosine monophosphate of phosphate transport and metabolism in BHK21C13 and BHK21Py cells.", "content": "Inhibition by N6, O2'-dibutyryl 3',5'-cyclic adenosine monophosphate of phosphate transport and metabolism in BHK21C13 and BHK21Py cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353480"}
{"pmid": "4353479", "title": "The isolation and characterization of gallium-binding granules from soft tissue tumors.", "content": "The isolation and characterization of gallium-binding granules from soft tissue tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353479"}
{"pmid": "4353481", "title": "Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.", "content": "Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353481"}
{"pmid": "4353482", "title": "A method for measuring DNA damage and repair in the liver in vivo.", "content": "A method for measuring DNA damage and repair in the liver in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353482"}
{"pmid": "4353483", "title": "Patterns of damage and repair of liver DNA induced by carcinogenic methylating agents in vivo.", "content": "Patterns of damage and repair of liver DNA induced by carcinogenic methylating agents in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353483"}
{"pmid": "4353484", "title": "A comparative study of the interaction between concanavalin A and mitochondria from normal and malignant cells.", "content": "A comparative study of the interaction between concanavalin A and mitochondria from normal and malignant cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353484"}
{"pmid": "4353486", "title": "The estimation of citrate in serum and urine using a citrate lyase technique.", "content": "The estimation of citrate in serum and urine using a citrate lyase technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353486"}
{"pmid": "4353485", "title": "Effect of hydrocortisone on cell viability, Epstein-Barr virus genome expression, and interferon synthesis in human lymphoblastoid cell lines.", "content": "Effect of hydrocortisone on cell viability, Epstein-Barr virus genome expression, and interferon synthesis in human lymphoblastoid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353485"}
{"pmid": "4353487", "title": "Radioimmunoassay of oestriol in pregnancy plasma.", "content": "Radioimmunoassay of oestriol in pregnancy plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353487"}
{"pmid": "4353488", "title": "The response to plant mitogens of two subpopulations of lymphocytes in a case of chronic lymphocytic leukaemia.", "content": "The response to plant mitogens of two subpopulations of lymphocytes in a case of chronic lymphocytic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353488"}
{"pmid": "4353490", "title": "Reversible blockage of specific synaptic transmission by localized and moderate cooling with a vacuum insulated probe connected to a closed circuit apparatus.", "content": "Reversible blockage of specific synaptic transmission by localized and moderate cooling with a vacuum insulated probe connected to a closed circuit apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353490"}
{"pmid": "4353489", "title": "Virus-specific immunoglobulins in multiple sclerosis.", "content": "Virus-specific immunoglobulins in multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353489"}
{"pmid": "4353491", "title": "Coordination: the key to rehabilitation.", "content": "Coordination: the key to rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353491"}
{"pmid": "4353492", "title": "Returning long-term patients to the community.", "content": "Returning long-term patients to the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353492"}
{"pmid": "4353493", "title": "A network of volunteers for community programs.", "content": "A network of volunteers for community programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353493"}
{"pmid": "4353494", "title": "A support group for maintaining chronic patients outside the hospital.", "content": "A support group for maintaining chronic patients outside the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353494"}
{"pmid": "4353495", "title": "Separation of cocaine, some of its metabolites and congeners on glass fibre sheets.", "content": "Separation of cocaine, some of its metabolites and congeners on glass fibre sheets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353495"}
{"pmid": "4353496", "title": "Agricultural fungicides. I. Identification of systemic fungicides using thin-layer chromatography.", "content": "Agricultural fungicides. I. Identification of systemic fungicides using thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353496"}
{"pmid": "4353497", "title": "Rapid determination of some plasma oxypurines using high-pressure liquid chromatography.", "content": "Rapid determination of some plasma oxypurines using high-pressure liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353497"}
{"pmid": "4353498", "title": "The effect of proteolytic enzymes on the induction of heterotopic bone formation by demineralized dentin in guinea pigs.", "content": "The effect of proteolytic enzymes on the induction of heterotopic bone formation by demineralized dentin in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353498"}
{"pmid": "4353500", "title": "Influence of gene 55 on the regulation of synthesis of some early enzymes in bacteriophage T4-infected escherichia coli.", "content": "Influence of gene 55 on the regulation of synthesis of some early enzymes in bacteriophage T4-infected escherichia coli. In Escherichia coli B infected with phage T4 with mutations in gene 55 the shut-off of synthesis of two early enzymes was found to be delayed 10 to 15 min as compared to wild-type T4 infection. The kinetics of early enzyme formation was very similar to that obtained after DNA-negative mutant infection. The transcription of gene 1 (one of the genes coded for early enzymes) ceased at 9 to 12 min after infection whether the gene 55 product was active or not, as determined by the time dependence of fluorouracil rescuability of DNA synthesis in cells infected with a gene 1 amber mutant. The synthesis of the major part of the early RNA species, determined by pulse-labeling with uracil-5-(3)H, was furthermore found to be regulated independently of gene 55. An explanation for the extended early enzyme synthesis in DNA-negative and gene 55 mutant infection is offered: translation of early messengers is restricted after about 12 min in wild-type infection, whereas in cells infected with DNA-negative or gene 55 mutants, i.e., the absence of late protein synthesis, early messengers direct the formation of early enzymes for a longer time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353500"}
{"pmid": "4353499", "title": "Characterization of two simian virus 40-specific RNA molecules from infected BS-C-1 cells.", "content": "Characterization of two simian virus 40-specific RNA molecules from infected BS-C-1 cells. Two discrete simian virus 40 (SV40) RNA species sedimenting at 19 and 16S, respectively, that are present in infected BS-C-1 cells were characterized with respect to the base composition and the ribonuclease T1 fingerprints. The base composition of the 19S SV40 RNA was found to be cytidylic acid (C), 23.0; adenylic acid (A), 28.3; guanylic acid (G), 23.9; and uridylic acid (U), 24.8; that of the 16S SV40 RNA was C, 19.3; A, 34.0; G, 22.0; and U, 24.7 mol%. Analysis of the ribonuclease T1 fingerprints indicated a difference in the base sequence of the 19 and 16S SV40 RNA. The presence of long sequences of adenylic acid residues (poly A) in these viral RNAs was confirmed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353499"}
{"pmid": "4353501", "title": "Adaptation of plaque assay methods to the in vitro quantitation of the radiation leukemia virus.", "content": "Adaptation of plaque assay methods to the in vitro quantitation of the radiation leukemia virus. A modification of the XC cell procedure for murine leukemia virus assay which yields quantitative data over a wide range of virus concentrations is described. By using serial passage of infected cell cultures and reversal of the plating sequence in the XC procedure, titers of radiation leukemia virus (RadLV) were obtained which were about 10-fold higher than those found by using the conventional assay. By using the modified procedure, it was observed that, even at high multiplicities of infection, less than 10% of the cells function as infective centers, although the proportion increases with serial passage. It was also observed that exposure of infected cells to UV light, which is commonly used to make plaques more visible in the conventional XC cell test, inhibits plaque formation in the RadLV system. Substitution of X irradiation for UV exposure improved plaque visibility without loss of sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353501"}
{"pmid": "4353502", "title": "Variants of simian virus 40-transformed 3T3 cells that are resistant to concanavalin A.", "content": "Variants of simian virus 40-transformed 3T3 cells that are resistant to concanavalin A. By treating populations of simian virus 40 (SV40)-transformed 3T3 cells with concanavalin A, variants have been isolated which are resistant to the killing action of the lectin. The variants (i) resemble 3T3 cells morphologically and in some of their growth characteristics; (ii) are not agglutinated by high concentrations of concanavalin A or wheat germ agglutinin, but can be rendered agglutinable by treatment with low concentrations of trypsin; (iii) bind the same number of concanavalin A molecules as 3T3 or SV3T3 cells; (iv) cannot be transformed by SV40 and are resistant to focus formation after infection with murine sarcoma virus; (v) contain SV40-specific T antigen and RNA and; (vi) yield wild-type SV40 virus after heterokaryon formation with BS-C-1 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353502"}
{"pmid": "4353503", "title": "Transcription of simian virus 40. II. Hybridization of RNA extracted from different lines of transformed cells to the separated strands of simian virus 40 DNA.", "content": "Transcription of simian virus 40. II. Hybridization of RNA extracted from different lines of transformed cells to the separated strands of simian virus 40 DNA. The amount of simian virus 40 (SV40) DNA present in various SV40-transformed mouse cell lines and \"revertants\" isolated from them was determined. The number of viral DNA copies in the different cell lines ranged from 1.35 to 8.75 copies per diploid quantity of mouse cell DNA and from 2.2 to 14 copies per cell. The revertants had the same number of viral DNA copies per diploid quantity of mouse cell DNA as their parental cell lines. (However, they showed an increased number of viral DNA copies per cell due to their increased amount of DNA.) By using separated strands of SV40 DNA, the extent of each DNA strand transcribed into stable RNA species was determined for the transformed and \"revertant\" cell lines. From 30 to 80% of the \"early\" strand and from 0 to 20% of the \"late\" strand was present as stable RNA species in the cell lines tested. There was no alteration in the pattern of the stable viral RNA species present in three concanavalin A-selected revertants, whereas in a fluorodeoxyuridine-selected revertant there appeared to be less viral-specific RNA present in the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353503"}
{"pmid": "4353504", "title": "Relationship between replication of simian virus 40 DNA and specific events of the host cell cycle.", "content": "Relationship between replication of simian virus 40 DNA and specific events of the host cell cycle. The relationship between replication of simian virus 40 (SV40) DNA and the various periods of the host-cell cycle was investigated in synchronized CV(1) cells. Cells synchronized through a double excess thymidine procedure were infected with SV40 at the beginning or the middle of S, or in G(2). The first viral progeny DNA molecules were in all instances detected approximately 20 h after release from the thymidine block, independent of the time of infection. The length of the early, prereplicative phase of the virus growth cycle therefore depended upon the period of the cell cycle at which the cells were infected. Infection with SV40 was also performed on cells obtained in early G(1) through selective detachment of cells in metaphase. As long as the cells were in G(1) at the time of infection, the first viral progeny DNA molecules were detected during the S period immediately following, whereas if infection took place once the cells had entered S, no progeny DNA molecule could be detected until the S period of the next cell cycle. These results suggest that the infected cell has to pass through a critical stage situated in late G(1) or early S before SV40 DNA replication can eventually be initiated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353504"}
{"pmid": "4353505", "title": "Simultaneous sudden death in infancy in identical twins.", "content": "Simultaneous sudden death in infancy in identical twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353505"}
{"pmid": "4353506", "title": "Adrenocortical function and skin pigmentation in idiopathic haemochromatosis.", "content": "Adrenocortical function and skin pigmentation in idiopathic haemochromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353506"}
{"pmid": "4353507", "title": "Experience with the Entamoeba histolytica fluorescent antibody test in Western Australia.", "content": "Experience with the Entamoeba histolytica fluorescent antibody test in Western Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353507"}
{"pmid": "4353508", "title": "Gas gangrene.", "content": "Gas gangrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353508"}
{"pmid": "4353510", "title": "Histochemistry of nucleic acids and proteins in cells of neuroectodermal tumours of different grades of malignancy.", "content": "Histochemistry of nucleic acids and proteins in cells of neuroectodermal tumours of different grades of malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353510"}
{"pmid": "4353511", "title": "Increase of EB virus positive cells in cultured Burkitt lymphoma cells after short-time exposure to heat.", "content": "Increase of EB virus positive cells in cultured Burkitt lymphoma cells after short-time exposure to heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353511"}
{"pmid": "4353513", "title": "Pleomorphic adenoma of the nasal septum.", "content": "Pleomorphic adenoma of the nasal septum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353513"}
{"pmid": "4353514", "title": "Dye staining of neural end-feed for light microscopy after glutaraldehyde fixation.", "content": "Dye staining of neural end-feed for light microscopy after glutaraldehyde fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353514"}
{"pmid": "4353515", "title": "Effects of adrenocorticotropic hormone and gonadotropins on urinary 17-ketosteroid production in the male pseudohermaphrodite rat.", "content": "Effects of adrenocorticotropic hormone and gonadotropins on urinary 17-ketosteroid production in the male pseudohermaphrodite rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353515"}
{"pmid": "4353516", "title": "Properties of mouse leukemia viruses. IV. Hemagglutination assay and characterization of hemagglutinating surface components.", "content": "Properties of mouse leukemia viruses. IV. Hemagglutination assay and characterization of hemagglutinating surface components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353516"}
{"pmid": "4353517", "title": "Properties of mouse leukemia viruses. V. Hemagglutination-inhibition and indirect hemagglutination tests.", "content": "Properties of mouse leukemia viruses. V. Hemagglutination-inhibition and indirect hemagglutination tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353517"}
{"pmid": "4353518", "title": "The membrane protein of influenza virus: extraction from virus and infected cell with acidic chloroform-methanol.", "content": "The membrane protein of influenza virus: extraction from virus and infected cell with acidic chloroform-methanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353518"}
{"pmid": "4353519", "title": "The evolution of new species of viral DNA during serial passage of simian virus 40 at high multiplicity.", "content": "The evolution of new species of viral DNA during serial passage of simian virus 40 at high multiplicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353519"}
{"pmid": "4353521", "title": "Mapping of base sequence heterologies between genomes from different adenovirus serotypes.", "content": "Mapping of base sequence heterologies between genomes from different adenovirus serotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353521"}
{"pmid": "4353520", "title": "Two types of target cells for transformation with avian myelocytomatosis virus.", "content": "Two types of target cells for transformation with avian myelocytomatosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353520"}
{"pmid": "4353524", "title": "Picornavirus receptors and picornavirus multiplication in human-mouse hybrid cell lines.", "content": "Picornavirus receptors and picornavirus multiplication in human-mouse hybrid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353524"}
{"pmid": "4353522", "title": "Preferential integration of simian virus 40 deoxyribonucleic acid into a particular size class of CV-1 cell deoxyribonucleic acid.", "content": "Preferential integration of simian virus 40 deoxyribonucleic acid into a particular size class of CV-1 cell deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353522"}
{"pmid": "4353525", "title": "Nonproducer clones of murine sarcoma virus transformed guinea pig embryo cells.", "content": "Nonproducer clones of murine sarcoma virus transformed guinea pig embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353525"}
{"pmid": "4353523", "title": "Symmetrical in vivo transcription of polyoma DNA and the separation of self-complementary viral and cell RNA.", "content": "Symmetrical in vivo transcription of polyoma DNA and the separation of self-complementary viral and cell RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353523"}
{"pmid": "4353530", "title": "Liquid scintillation counting of 14C- and 3H-labeled samples on solid supports: a general solution of the problem.", "content": "Liquid scintillation counting of 14C- and 3H-labeled samples on solid supports: a general solution of the problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353530"}
{"pmid": "4353531", "title": "A quantitative estimation of degree of purity of preparations of subcellular structures.", "content": "A quantitative estimation of degree of purity of preparations of subcellular structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353531"}
{"pmid": "4353533", "title": "Detection of methanesulfonic acid in ethyl methanesulfonate.", "content": "Detection of methanesulfonic acid in ethyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353533"}
{"pmid": "4353532", "title": "Isolation of intact spinach chloroplasts in the CF-6 continuous-flow zonal rotor; implications for membrane-bound organelles.", "content": "Isolation of intact spinach chloroplasts in the CF-6 continuous-flow zonal rotor; implications for membrane-bound organelles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353532"}
{"pmid": "4353534", "title": "A sensitive and specific method for the measurement of monophosphoinositide at a microregional level in brain.", "content": "A sensitive and specific method for the measurement of monophosphoinositide at a microregional level in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353534"}
{"pmid": "4353535", "title": "An automated fluorescence method for determination of K+-dependent phosphatase.", "content": "An automated fluorescence method for determination of K+-dependent phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353535"}
{"pmid": "4353536", "title": "Fatty acid composition of neutral lipids and phospholipids of enamel and dentine from rat incisors and molars.", "content": "Fatty acid composition of neutral lipids and phospholipids of enamel and dentine from rat incisors and molars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353536"}
{"pmid": "4353537", "title": "The alveolar macrophage and its role in toxicology.", "content": "The alveolar macrophage and its role in toxicology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353537"}
{"pmid": "4353539", "title": "The response of the multiple forms of lactate dehydrogenase to drugs.", "content": "The response of the multiple forms of lactate dehydrogenase to drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353539"}
{"pmid": "4353538", "title": "Some developmental observations on the effects of prolonged deprivation of low-voltage fast-wave sleep in the deermouse, Peromyscus maniculatus bairdi.", "content": "Some developmental observations on the effects of prolonged deprivation of low-voltage fast-wave sleep in the deermouse, Peromyscus maniculatus bairdi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353538"}
{"pmid": "4353542", "title": "Neutralizing antibody response in bovine serum and nasal and salivary secretions after immunization with live or inactivated food-and-mouth disease virus.", "content": "Neutralizing antibody response in bovine serum and nasal and salivary secretions after immunization with live or inactivated food-and-mouth disease virus. Calves develop nasal and salivary neutralizing antibodies against foot-and-mouth disease virus after nasal inoculation with live virus. Nasal and salivary antibody was not detected after exposure to inactive virus. Serum antibodies were induced by live and inactive virus given subcutaneously. Passively acquired antibodies were detected as long as 7 months after birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353542"}
{"pmid": "4353541", "title": "Further studies on the influence of steroids on viral infection in mice.", "content": "Further studies on the influence of steroids on viral infection in mice. Certain steroids have been reported to enhance experimental viral infections, whereas others have little or no effect. Interference with the interferon system has been suggested as a possible mechanism for the viral infection-enhancing (VIE) activity of hormones. In the present study, steroids (prednisolone, progesterone, testosterone) which had no effect on MM virus infection demonstrated VIE activity against Mayaro virus infection. It is suggested that the VIE activity of a hormone may be dependent on the viral agent used for challenge. Data are also presented which suggest that, in addition to interference with the interferon system, the VIE activity of steroid hormones may be the result of at least two other actions: (i) alteration of cell membranes; (ii) stimulation of initial viral replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353541"}
{"pmid": "4353543", "title": "Studies of the antigenic relationships of the new human papovaviruses by electron microscopy agglutination.", "content": "Studies of the antigenic relationships of the new human papovaviruses by electron microscopy agglutination. Virus-antibody interactions observed by electron microscopy show that new human papovavirus isolates are antigenically distinct, but share common antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353543"}
{"pmid": "4353544", "title": "Analytical isotachophoresis in capillary tubes. Transformation of pyruvate to succinate by calf heart mitochondrial enzymes.", "content": "Analytical isotachophoresis in capillary tubes. Transformation of pyruvate to succinate by calf heart mitochondrial enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353544"}
{"pmid": "4353547", "title": "Inferior venacavograms and renal venograms in the management of renal tumors.", "content": "Inferior venacavograms and renal venograms in the management of renal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353547"}
{"pmid": "4353546", "title": "Polymorphonuclear leukocyte collagenase: localization in granules subjected to zonal centrifugation.", "content": "Polymorphonuclear leukocyte collagenase: localization in granules subjected to zonal centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353546"}
{"pmid": "4353545", "title": "Availability of magnesium: balance studies in rats with various inorganic magnesium salts.", "content": "Availability of magnesium: balance studies in rats with various inorganic magnesium salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353545"}
{"pmid": "4353548", "title": "Increasing sensitivity rates of urinary gram-negative bacilli to antimicrobials.", "content": "Increasing sensitivity rates of urinary gram-negative bacilli to antimicrobials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353548"}
{"pmid": "4353549", "title": "Arteriography of Wilms tumor.", "content": "Arteriography of Wilms tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353549"}
{"pmid": "4353550", "title": "Regulation of levels of guanosine cyclic 3',5'-monophosphate in the central nervous system: effects of depolarizing agents.", "content": "Regulation of levels of guanosine cyclic 3',5'-monophosphate in the central nervous system: effects of depolarizing agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353550"}
{"pmid": "4353540", "title": "Fatty acid profiles of cells from the insect cell line IPRL-21 (Spodoptera frugiperda) and of the tissue culture medium after repeated use.", "content": "Fatty acid profiles of cells from the insect cell line IPRL-21 (Spodoptera frugiperda) and of the tissue culture medium after repeated use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353540"}
{"pmid": "4353551", "title": "Thyrotoxic periodic paralysis. Function of sarcoplasmic reticulum and muscle glycogen.", "content": "Thyrotoxic periodic paralysis. Function of sarcoplasmic reticulum and muscle glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353551"}
{"pmid": "4353553", "title": "Effect of Mg++ on neuromuscular transmission in the Eaton-Lambert syndrome.", "content": "Effect of Mg++ on neuromuscular transmission in the Eaton-Lambert syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353553"}
{"pmid": "4353552", "title": "Neurologic manifestations in tropical sprue. A clinical and electrodiagnostic study.", "content": "Neurologic manifestations in tropical sprue. A clinical and electrodiagnostic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353552"}
{"pmid": "4353554", "title": "Correlative insulin and glucagon secretion of the perfused rat pancreas following pituitary peptides.", "content": "Correlative insulin and glucagon secretion of the perfused rat pancreas following pituitary peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353554"}
{"pmid": "4353555", "title": "Early effects of testosterone on phospholipid metabolism in the seminal vesicles of immature rats.", "content": "Early effects of testosterone on phospholipid metabolism in the seminal vesicles of immature rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353555"}
{"pmid": "4353557", "title": "Differences in the age-dependent development and sexual differentiation of soluble and membrane-bound activities of 3alpha- and 3beta-hydroxysteroid-dehydrogenase in rat liver.", "content": "Differences in the age-dependent development and sexual differentiation of soluble and membrane-bound activities of 3alpha- and 3beta-hydroxysteroid-dehydrogenase in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353557"}
{"pmid": "4353556", "title": "Cyclic AMP and gastrointestinal hormones. Studies in isolated pancreatic islets.", "content": "Cyclic AMP and gastrointestinal hormones. Studies in isolated pancreatic islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353556"}
{"pmid": "4353558", "title": "Long-term ADH-treatment of rats with genetic diabetes insipidus.", "content": "Long-term ADH-treatment of rats with genetic diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353558"}
{"pmid": "4353559", "title": "In vivo \"radioimmunoassay\" of aldosterone in rats.", "content": "In vivo \"radioimmunoassay\" of aldosterone in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353559"}
{"pmid": "4353560", "title": "A simple and sensitive radioimmunoassay for plasma angiotensin II.", "content": "A simple and sensitive radioimmunoassay for plasma angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353560"}
{"pmid": "4353561", "title": "Response of plasma aldosterone to various stimuli in the angiotensin II-immune rabbit.", "content": "Response of plasma aldosterone to various stimuli in the angiotensin II-immune rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353561"}
{"pmid": "4353562", "title": "Relationships between weight changes and renin, aldosterone, estrogens and progesterone in cyclical edema.", "content": "Relationships between weight changes and renin, aldosterone, estrogens and progesterone in cyclical edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353562"}
{"pmid": "4353563", "title": "PTH-infusion and estimation of urinary cAMP in hyperparathyroidism.", "content": "PTH-infusion and estimation of urinary cAMP in hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353563"}
{"pmid": "4353564", "title": "Suppression and stimulation of plasma testosterone and DHT in hirsute women.", "content": "Suppression and stimulation of plasma testosterone and DHT in hirsute women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353564"}
{"pmid": "4353566", "title": "Lipolytically active peptides from hog pituitary glands.", "content": "Lipolytically active peptides from hog pituitary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353566"}
{"pmid": "4353565", "title": "Differential diagnosis of female hirsutism, Cushing's and Conn's syndrome. Quantitative sequential scintigraphy of the adrenals with 131-J-19-iodocholesterol.", "content": "Differential diagnosis of female hirsutism, Cushing's and Conn's syndrome. Quantitative sequential scintigraphy of the adrenals with 131-J-19-iodocholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353565"}
{"pmid": "4353567", "title": "Fine structure of corticotrophic cells and of pituitary adenomas in Cushing's syndrome.", "content": "Fine structure of corticotrophic cells and of pituitary adenomas in Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353567"}
{"pmid": "4353568", "title": "Isolated pituitary cells: ACTH secretion and synthesis.", "content": "Isolated pituitary cells: ACTH secretion and synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353568"}
{"pmid": "4353569", "title": "Contribution on regulation of corticotrophic partial function. Reference to an active negative regulation.", "content": "Contribution on regulation of corticotrophic partial function. Reference to an active negative regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353569"}
{"pmid": "4353570", "title": "Human pharmacological studies with a new synthetic corticotrophic peptide consisting of 18 amino acids.", "content": "Human pharmacological studies with a new synthetic corticotrophic peptide consisting of 18 amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353570"}
{"pmid": "4353571", "title": "ACTH determinations before and after selective removal of pituitary adenomas in Nelson's syndrome.", "content": "ACTH determinations before and after selective removal of pituitary adenomas in Nelson's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353571"}
{"pmid": "4353572", "title": "Cortisol, cortisone, and corticosterone in plasma following ACTH-stimulation during the first 6 hours of life.", "content": "Cortisol, cortisone, and corticosterone in plasma following ACTH-stimulation during the first 6 hours of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353572"}
{"pmid": "4353573", "title": "Studies on cyclic adenosine 3':5' monophosphate concentrations in human cervical mucus.", "content": "Studies on cyclic adenosine 3':5' monophosphate concentrations in human cervical mucus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353573"}
{"pmid": "4353574", "title": "Species differences in luteinizing hormone as infered from slope variations in a radioligand receptor assay.", "content": "Species differences in luteinizing hormone as infered from slope variations in a radioligand receptor assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353574"}
{"pmid": "4353576", "title": "Dihydrotestosterone receptor in human mammary cancer.", "content": "Dihydrotestosterone receptor in human mammary cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353576"}
{"pmid": "4353575", "title": "Radioligand receptor assay for the determination of LH and HCG activities utilizing rat ovarian receptors.", "content": "Radioligand receptor assay for the determination of LH and HCG activities utilizing rat ovarian receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353575"}
{"pmid": "4353577", "title": "Interrelationship of two microsomal estrogen receptor molecules.", "content": "Interrelationship of two microsomal estrogen receptor molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353577"}
{"pmid": "4353578", "title": "In-vitro corticosteroid synthesis in rat adrenals. I. Results indicating (an) alternative pathway(s) of synthesis without the intermediates cholesterol, pregnenolone and progesterone.", "content": "In-vitro corticosteroid synthesis in rat adrenals. I. Results indicating (an) alternative pathway(s) of synthesis without the intermediates cholesterol, pregnenolone and progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353578"}
{"pmid": "4353579", "title": "The influence of ACTH and HCG on the steroidogenesis of fetal adrenals in vitro.", "content": "The influence of ACTH and HCG on the steroidogenesis of fetal adrenals in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353579"}
{"pmid": "4353581", "title": "Oscillatory glycolysis in yeast: the pattern of phase resetting by oxygen.", "content": "Oscillatory glycolysis in yeast: the pattern of phase resetting by oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353581"}
{"pmid": "4353580", "title": "Pathways of carbohydrate metabolism in Tetrahymena. Subcellular distribution and properties of hexokinase, aldolase and alpha-glycerophosphate dehydrogenase.", "content": "Pathways of carbohydrate metabolism in Tetrahymena. Subcellular distribution and properties of hexokinase, aldolase and alpha-glycerophosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353580"}
{"pmid": "4353582", "title": "Bull semen nicotinamide adenine dinucleotide nucleosidase. IV. Nonpolar interactions of inhibitors with the substrate binding site.", "content": "Bull semen nicotinamide adenine dinucleotide nucleosidase. IV. Nonpolar interactions of inhibitors with the substrate binding site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353582"}
{"pmid": "4353583", "title": "ESR probing of macromolecules: spin-labeling of the active sites of the proteolytic serine enzymes.", "content": "ESR probing of macromolecules: spin-labeling of the active sites of the proteolytic serine enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353583"}
{"pmid": "4353584", "title": "ESR probing of macromolecules: spin label study of the conformational integrity and transitions in modified alpha-chymotrypsin.", "content": "ESR probing of macromolecules: spin label study of the conformational integrity and transitions in modified alpha-chymotrypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353584"}
{"pmid": "4353585", "title": "Mechanism of action of a respiratory inhibitor from the gill tissue of the sporulating common mushroom, Agaricus bisporus.", "content": "Mechanism of action of a respiratory inhibitor from the gill tissue of the sporulating common mushroom, Agaricus bisporus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353585"}
{"pmid": "4353587", "title": "A study of postoperative cytostatic medication in patients with operable carcinoma of the lung.", "content": "A study of postoperative cytostatic medication in patients with operable carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353587"}
{"pmid": "4353588", "title": "Comparison of the effects of two phosphodiesterase inhibitors, theophylline and papaverine, on blood glucose, plasma FFA and glycerol in the rat.", "content": "Comparison of the effects of two phosphodiesterase inhibitors, theophylline and papaverine, on blood glucose, plasma FFA and glycerol in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353588"}
{"pmid": "4353593", "title": "Ocular pathology of GM2 gangliosidosis--Type 2 (Sandhoff's disease).", "content": "Ocular pathology of GM2 gangliosidosis--Type 2 (Sandhoff's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353593"}
{"pmid": "4353594", "title": "Cyclic AMP inhibition of cytotoxin (\"lymphotoxin\") elaboration by stimulated lymphocytes.", "content": "Cyclic AMP inhibition of cytotoxin (\"lymphotoxin\") elaboration by stimulated lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353594"}
{"pmid": "4353597", "title": "Electron microscopy of endothelial and epithelial components of the lungs: correlations of structure and function.", "content": "Electron microscopy of endothelial and epithelial components of the lungs: correlations of structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353597"}
{"pmid": "4353596", "title": "Calcium metabolism at the cellular level.", "content": "Calcium metabolism at the cellular level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353596"}
{"pmid": "4353598", "title": "Mechanism of action of cytochrome c oxidase and its implications for energy conservation.", "content": "Mechanism of action of cytochrome c oxidase and its implications for energy conservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353598"}
{"pmid": "4353599", "title": "Electron transfer across membranes and energy coupling.", "content": "Electron transfer across membranes and energy coupling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353599"}
{"pmid": "4353601", "title": "Nucleic acids. 14. Synthesis and antiviral activity of some 5'-esters of 9-beta-D-arabinofuranosyladenine (ara-A).", "content": "Nucleic acids. 14. Synthesis and antiviral activity of some 5'-esters of 9-beta-D-arabinofuranosyladenine (ara-A).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353601"}
{"pmid": "4353602", "title": "Factors that influence the antagonistic properties of angiotensin II antagonists.", "content": "Factors that influence the antagonistic properties of angiotensin II antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353602"}
{"pmid": "4353603", "title": "Uptake of androgen analogs by prostate tissue.", "content": "Uptake of androgen analogs by prostate tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353603"}
{"pmid": "4353604", "title": "A synthesis of noformycin.", "content": "A synthesis of noformycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353604"}
{"pmid": "4353605", "title": "Seromucoid and albumin levels in maternal and cord serum in relation to obstetric stress.", "content": "Seromucoid and albumin levels in maternal and cord serum in relation to obstetric stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353605"}
{"pmid": "4353606", "title": "Cattle and Culicoides biting midges as possible overwintering hosts of bluetongue virus.", "content": "Cattle and Culicoides biting midges as possible overwintering hosts of bluetongue virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353606"}
{"pmid": "4353607", "title": "Cytomegalovirus: conversion of nonpermissive cells to a permissive state for virus replication.", "content": "Cytomegalovirus: conversion of nonpermissive cells to a permissive state for virus replication. Human embryonic kidney cells are epithelioid cells which are normally nonpermissive for in vitro replication of human cytomegalovirus. These cells were converted to a permissive state for the virus by prior treatment with 5-iodo-2'-deoxyuridine. When this method was used, a nonpermissive cell was made permissive to an infecting virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353607"}
{"pmid": "4353600", "title": "Utilization of somatic cell hybrids for genetic studies in man.", "content": "Utilization of somatic cell hybrids for genetic studies in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353600"}
{"pmid": "4353613", "title": "I-cell disease, mucolipidosis II. Pathological, histochemical, ultrastructural and biochemical observations in four cases.", "content": "I-cell disease, mucolipidosis II. Pathological, histochemical, ultrastructural and biochemical observations in four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353613"}
{"pmid": "4353616", "title": "Technetium-99m labelled pyrophosphate: a simple and reproducible bone scanning agent.", "content": "Technetium-99m labelled pyrophosphate: a simple and reproducible bone scanning agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353616"}
{"pmid": "4353617", "title": "Virological studies in Reiter's disease.", "content": "Virological studies in Reiter's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353617"}
{"pmid": "4353619", "title": "Sexual transmission of intestinal parasites.", "content": "Sexual transmission of intestinal parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353619"}
{"pmid": "4353618", "title": "Characterization of genital strains of Herpesvirus hominis.", "content": "Characterization of genital strains of Herpesvirus hominis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353618"}
{"pmid": "4353620", "title": "Progress in myasthenia gravis.", "content": "Progress in myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353620"}
{"pmid": "4353621", "title": "Hypothesis: breast cancer regression under oestrogen therapy.", "content": "Hypothesis: breast cancer regression under oestrogen therapy. Recent reports have thrown doubt on both of the major mechanisms which have been suggested for the regression of breast cancer under high-dosage oestrogen therapy-a direct effect on binding sites and an indirect inhibition of prolactin release. A searching review on the clinical response of 407 patients with advanced breast cancer treated by oestrogen therapy under my direction showed certain anomalies, including age determined tumour inhibition and stimulation, dose dependence of tumour inhibition and stimulation, differential site sensitivity, and tumour regression with oestrogen withdrawal. The hypothesis usually postulated to explain these anomalies is that the tumour may in the same individual be composed of multiple genetically distinct clones of cells. It is suggested instead that the effect of high-dosage oestrogen therapy in breast cancer may depend critically on the absolute and relative concentrations of prolactin and oestrogen actively available at the tumour. On this basis the clinical manifestation of tumour stimulation in response to oestrogen administration suggests that the oestrogen concentration at the target is inadequate. Differences in site sensitivity in the same patient may depend on tumoral factors such as the level of oestradiol and prolactin binding receptors in the tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353621"}
{"pmid": "4353622", "title": "Ultrastructure of cysts of E. histolytica.", "content": "Ultrastructure of cysts of E. histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353622"}
{"pmid": "4353623", "title": "Ultrastructure of E. histolytica--strain NIH 200.", "content": "Ultrastructure of E. histolytica--strain NIH 200.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353623"}
{"pmid": "4353624", "title": "Specific binding of (3H) lysine-vasopressin to pig kidney plasma membranes. Relationship of receptor occupancy to adenylate cyclase activation.", "content": "Specific binding of (3H) lysine-vasopressin to pig kidney plasma membranes. Relationship of receptor occupancy to adenylate cyclase activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353624"}
{"pmid": "4353625", "title": "Studies on the mechanism of action of the gal repressor.", "content": "Studies on the mechanism of action of the gal repressor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353625"}
{"pmid": "4353626", "title": "Mechanism of activation of a cyclic adenosine 3':5'-monophosphate phosphodiesterase from bovine heart by calcium ions. Identification of the protein activator as a Ca2+ binding protein.", "content": "Mechanism of activation of a cyclic adenosine 3':5'-monophosphate phosphodiesterase from bovine heart by calcium ions. Identification of the protein activator as a Ca2+ binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353626"}
{"pmid": "4353627", "title": "Studies on calciferol metabolism. 8. Evidence for a cytoplasmic receptor for 1,25-dihydroxy-vitamin D3 in the intestinal mucosa.", "content": "Studies on calciferol metabolism. 8. Evidence for a cytoplasmic receptor for 1,25-dihydroxy-vitamin D3 in the intestinal mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353627"}
{"pmid": "4353628", "title": "Succinic semialdehyde dehydrogenase from a Pseudomonas species. I. Purification and chemical properties.", "content": "Succinic semialdehyde dehydrogenase from a Pseudomonas species. I. Purification and chemical properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353628"}
{"pmid": "4353629", "title": "Succinic semialdehyde dehydrogenase from a Pseudomonas species. II. Physical and immunochemical properties of the enzyme.", "content": "Succinic semialdehyde dehydrogenase from a Pseudomonas species. II. Physical and immunochemical properties of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353629"}
{"pmid": "4353630", "title": "The oxidation of catechols by reduced flavins and dehydrogenases. An electron spin resonance study of the kinetics and initial products of oxidation.", "content": "The oxidation of catechols by reduced flavins and dehydrogenases. An electron spin resonance study of the kinetics and initial products of oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353630"}
{"pmid": "4353631", "title": "The kinetics and mechanism of reduction of electron transfer proteins and other compounds of biological interest by dithionite.", "content": "The kinetics and mechanism of reduction of electron transfer proteins and other compounds of biological interest by dithionite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353631"}
{"pmid": "4353632", "title": "Kinetic studies on the substrate reduction of xanthine oxidase.", "content": "Kinetic studies on the substrate reduction of xanthine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353632"}
{"pmid": "4353633", "title": "Steroid structure and androgenic activity. Specificities involved in the receptor binding and nuclear retention of various androgens.", "content": "Steroid structure and androgenic activity. Specificities involved in the receptor binding and nuclear retention of various androgens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353633"}
{"pmid": "4353634", "title": "Receptors for thyrotropin-releasing hormone in prolactin producing rat pituitary cells in culture.", "content": "Receptors for thyrotropin-releasing hormone in prolactin producing rat pituitary cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353634"}
{"pmid": "4353635", "title": "Stimulatory and inhibitory effects of guanyl nucleotides on fat cell adenylate cyclase.", "content": "Stimulatory and inhibitory effects of guanyl nucleotides on fat cell adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353635"}
{"pmid": "4353636", "title": "Estrogen receptor in a human cell line (MCF-7) from breast carcinoma.", "content": "Estrogen receptor in a human cell line (MCF-7) from breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353636"}
{"pmid": "4353637", "title": "Inhibition of cellular differentiation by phospholipase C. I. Effects of the enzyme on myogenesis and chondrogenesis in vitro.", "content": "Inhibition of cellular differentiation by phospholipase C. I. Effects of the enzyme on myogenesis and chondrogenesis in vitro. In cell culture, a partially purified commercial preparation of phospholipase C (PLC) from Clostridium welchii inhibited fusion of myoblasts at concentrations of 12-50 microg per ml. At lower concentrations, PLC-treated cultures were indistinguishable from controls, and at concentrations above 100 microg per ml, PLC-treated cells detached from their substrates. The effect was reversible and fusion resumed approximately one cell cycle time after removal of the enzyme. Neither the percent of cells in the mitotic cycle nor the duration of the different phases of the cycle were altered by PLC at concentrations which inhibited fusion. Cell motility was not reduced by the enzyme. Unfused, PLC-treated myoblasts were virtually indistinguishable in ultrastructure from untreated cells just before fusion. In the presence of PLC, mononucleated myogenic cells did not synthesize thick (150 A) filaments. Treatment of culture medium with insolubilized commercial PLC did not abolish the capacity of the medium to support myogenesis. Chondrocytes treated with PLC divided repeatedly but failed to synthesize metachromatic matrix and failed to incorporate labeled sulfate into chondroitin sulfate. PLC was further purified by chromatography on Sephadex G-100. The resulting preparation was free of detectable protease, yielded one band on SDS-acrylamide gel electrophoresis, and displayed all of the biological activities of the less pure material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353637"}
{"pmid": "4353640", "title": "A radioimmunoassay for beta-melanocyte-stimulating hormone in human plasma.", "content": "A radioimmunoassay for beta-melanocyte-stimulating hormone in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353640"}
{"pmid": "4353638", "title": "Establishment and characterization of ethidium bromide resistance in simian virus 40-transformed hamster cells. Effects on mitochondria in vivo.", "content": "Establishment and characterization of ethidium bromide resistance in simian virus 40-transformed hamster cells. Effects on mitochondria in vivo. This study describes the isolation and subsequent characterization of four mammalian cell lines resistant to ethidium bromide (EB). Treatment of the simian virus 40- (SV40) transformed hamster cell line F5-1 first led to the establishment of the F2 cell line, which is resistant to 2 microg EB/ml. At this concentration cytochromes c and b are present in almost normal or only slightly diminished amounts, whereas cytochromes a + a(3) show an obvious decrease. The mitochondria of the F2 cell show a normal ultrastructure, not distinct from the parental cell line F5-1, and contain closed circular DNA. The sensitive parental F5-1 cells, however, when exposed to the same dye concentration exhibit the typical EB-induced ultrastructural changes in the mitochondria, and no more component I mitochondrial DNA can be demonstrated. 1 yr after establishment we derived from the F2 cell three more cell lines, resistant against 4, 8, and 16 microg of EB/ml. These cell lines, termed F4, F8, and F16, respectively, also revealed relatively intact-appearing mitochondria, although distinguishable from F5-1 and F2 mitochondria by a more condensed or unorthodox cristae conformation. F4, F8, and F16 cell lines contained closed circular mitochondrial DNA in the same position as that of the parental F5-1 cells, when analyzed in an isopycnic CsCl-EB gradient. A small shoulder at the lower density side of the DNA I peaks was observed. The newly acquired drug resistance of the F cells is hereditarily transmitted to the progeny cells and retained even after a period of growth in EB-free medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353638"}
{"pmid": "4353642", "title": "Distribution of fructose, citric acid, sialic acid and lipids in male accessory glands of the hamster, Mesocricetus auratus.", "content": "Distribution of fructose, citric acid, sialic acid and lipids in male accessory glands of the hamster, Mesocricetus auratus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353642"}
{"pmid": "4353641", "title": "Incorporation of 32P into phospholipids of the hypothalamo-neuro-hypophysial system and subcellular distribution of labelled phospholipids in the rat neural lobe.", "content": "Incorporation of 32P into phospholipids of the hypothalamo-neuro-hypophysial system and subcellular distribution of labelled phospholipids in the rat neural lobe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353641"}
{"pmid": "4353639", "title": "Embryonic chick intestine in organ culture. A unique system for the study of the intestinal calcium absorptive mechanism.", "content": "Embryonic chick intestine in organ culture. A unique system for the study of the intestinal calcium absorptive mechanism. Duodena from 20-day-old chick embryos can be maintained in large scale organ culture on specially designed stainless-steel grids in contact with serum-free medium for 48 h with excellent preservation of mucosal structure at both the light and electron microscope levels. Although mitotic rate was subnormal, several other factors attest to the essential viability of the cultured intestine: L-leucine incorporation into protein, as well as the synthesis of a specific vitamin D(3)-induced calcium-binding protein (CaBP), increased over a 48-h culture period, and the electropotential gradient across the intestine was maintained throughout the culture period as was a concentration gradient for calcium. The tissue responded to vitamin D(3) in the medium by synthesizing the calcium-binding protein within 6 h and by exhibiting enhanced (45)Ca uptake within 12-24 h. Concentrations of vitamin D(3), or its 25-hydroxylated derivative, higher than necessary for CaBP induction, also increased the activity of alkaline phosphatase. The 1,25-dihydroxylated derivative of vitamin D(3), at a level extremely potent in CaBP induction, did not stimulate alkaline phosphatase. Mucosal to serosal transport of (45)Ca could also be measured in everted duodenal sacs, subsequent to culture under similar conditions, and was also increased by vitamin D(3) in the medium. Other embryonic organs, esophagus, stomach, liver, pancreas, lung, skin, and muscle, did not produce CaBP in response to vitamin D(3) in the culture medium. However, CaBP-synthesizing capacity was present in the entire intestinal tract, exclusive of the rectum. (59)Fe and (32)P uptake by cultured duodenum were also stimulated by vitamin D(3). The system has proven quite useful in the study of the vitamin D-mediated calcium absorptive mechanism but should be applicable to the study of the absorption of other nutrients, drugs, hormones, etc., as well as other studies of intestinal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353639"}
{"pmid": "4353643", "title": "The influence of carbon dioxide on the growth of obligate and facultative anaerobes on solid media.", "content": "The influence of carbon dioxide on the growth of obligate and facultative anaerobes on solid media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353643"}
{"pmid": "4353644", "title": "Resistotyping of Shigella sonnei.", "content": "Resistotyping of Shigella sonnei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353644"}
{"pmid": "4353645", "title": "Intracellular growth and type variation of Neisseria gonorrhoeae in tissue cell-cultures.", "content": "Intracellular growth and type variation of Neisseria gonorrhoeae in tissue cell-cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353645"}
{"pmid": "4353646", "title": "Estimation of the concentration of low density lipoprotein cholesterol and very low density lipoprotein cholesterol by selective adsorption from serum with magnesium compounds.", "content": "Estimation of the concentration of low density lipoprotein cholesterol and very low density lipoprotein cholesterol by selective adsorption from serum with magnesium compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353646"}
{"pmid": "4353647", "title": "Effect of thyrotropin and of LATS on mouse thyroid cyclic AMP.", "content": "Effect of thyrotropin and of LATS on mouse thyroid cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353647"}
{"pmid": "4353648", "title": "Monolayer culture of a human pancreatic beta-cell adenoma.", "content": "Monolayer culture of a human pancreatic beta-cell adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353648"}
{"pmid": "4353650", "title": "Mutations affecting growth of the Escherichia coli cell under a condition of DNA polymerase I-deficiency.", "content": "Mutations affecting growth of the Escherichia coli cell under a condition of DNA polymerase I-deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353650"}
{"pmid": "4353653", "title": "Subfornical organ: site of drinking elicitation by angiotensin II.", "content": "Subfornical organ: site of drinking elicitation by angiotensin II. Angiotensin II applied directly to the subfornical organ in a dose as small as 0.1 nanogram elicited short-latency drinking behavior in water-sated rats. Lesions in the body of this structure blocked drinking induced by angiotensin II applied to the basal telencephalon (including preoptic area). These results call attention to the subfornical organ as an important central nervous structure involved in the conrol of drinking behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353653"}
{"pmid": "4353654", "title": "Familial gouty malignant uric acid lithiasis due to mutant phosphoribosylpyrophosphate synthetase.", "content": "Familial gouty malignant uric acid lithiasis due to mutant phosphoribosylpyrophosphate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353654"}
{"pmid": "4353659", "title": "Nitrogen transformations in soils. I. In sandy soil under barley and peanut in a two years' rotation.", "content": "Nitrogen transformations in soils. I. In sandy soil under barley and peanut in a two years' rotation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353659"}
{"pmid": "4353660", "title": "Nitrogen transformation in soils. II. In sandy soil under horse-bean and sesame in a two years' rotation.", "content": "Nitrogen transformation in soils. II. In sandy soil under horse-bean and sesame in a two years' rotation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353660"}
{"pmid": "4353661", "title": "Centrally induced drinking: comparison of angiotensin II- and carbachol-sensitive sites in rats.", "content": "Centrally induced drinking: comparison of angiotensin II- and carbachol-sensitive sites in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353661"}
{"pmid": "4353662", "title": "pH dependence of reversal potential for acetylcholine-induced currents in neurons.", "content": "pH dependence of reversal potential for acetylcholine-induced currents in neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353662"}
{"pmid": "4353663", "title": "Spontaneous cytomegalovirus mononucleosis. Clinical and laboratory observations in nine cases.", "content": "Spontaneous cytomegalovirus mononucleosis. Clinical and laboratory observations in nine cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353663"}
{"pmid": "4353664", "title": "Cytomegalovirus infection in previously healthy adults.", "content": "Cytomegalovirus infection in previously healthy adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353664"}
{"pmid": "4353665", "title": "Adrenal ablation by venous catheter.", "content": "Adrenal ablation by venous catheter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353665"}
{"pmid": "4353666", "title": "Effect of ionophorous antibiotics (nigericin, gramicidin and valinomycin) on cyclic AMP synthesis in rat adipose tissue.", "content": "Effect of ionophorous antibiotics (nigericin, gramicidin and valinomycin) on cyclic AMP synthesis in rat adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353666"}
{"pmid": "4353667", "title": "Effect of highly specific inhibitors of oxidative phosphorylation, dicyclohexylcarbodiimide, antimycin A and piercidin A, on cyclic AMP accumulation induced by noradrenaline and theophylline in rat adipose tissue.", "content": "Effect of highly specific inhibitors of oxidative phosphorylation, dicyclohexylcarbodiimide, antimycin A and piercidin A, on cyclic AMP accumulation induced by noradrenaline and theophylline in rat adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353667"}
{"pmid": "4353668", "title": "Inhibition of hypoxanthine transport by chlorpromazine and SKF 525-A in cell culture.", "content": "Inhibition of hypoxanthine transport by chlorpromazine and SKF 525-A in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353668"}
{"pmid": "4353669", "title": "Formation of nucleotides of (6-14C)allopurinol and (6-14C)oxipurinol in rat tissues and effects on uridine nucleotide pools.", "content": "Formation of nucleotides of (6-14C)allopurinol and (6-14C)oxipurinol in rat tissues and effects on uridine nucleotide pools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353669"}
{"pmid": "4353671", "title": "Effect of ethoxyquin on the carbon tetrachloride-induced changes in rat hepatic microsomal enzymes.", "content": "Effect of ethoxyquin on the carbon tetrachloride-induced changes in rat hepatic microsomal enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353671"}
{"pmid": "4353672", "title": "Bilateral patellar metastases from carcinoma of the male breast.", "content": "Bilateral patellar metastases from carcinoma of the male breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353672"}
{"pmid": "4353670", "title": "Interactions of acetaldehyde, ethyl alcohol and oxybarbiturates affecting mitochondrial functions.", "content": "Interactions of acetaldehyde, ethyl alcohol and oxybarbiturates affecting mitochondrial functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353670"}
{"pmid": "4353678", "title": "Equine coital exanthema in the United Kingdom.", "content": "Equine coital exanthema in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353678"}
{"pmid": "4353679", "title": "Diagnosing the state of the diagnostic function: an analysis of the literature.", "content": "Diagnosing the state of the diagnostic function: an analysis of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353679"}
{"pmid": "4353680", "title": "Psychiatric aftercare clinic effectiveness as a function of patient demographic characteristics.", "content": "Psychiatric aftercare clinic effectiveness as a function of patient demographic characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353680"}
{"pmid": "4353682", "title": "Identification of a critical period during the S phase for activation of the Epstein-Barr virus by 5-iododeoxyuridine.", "content": "Identification of a critical period during the S phase for activation of the Epstein-Barr virus by 5-iododeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353682"}
{"pmid": "4353683", "title": "Spare gonadotrophin receptors in rat testis.", "content": "Spare gonadotrophin receptors in rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353683"}
{"pmid": "4353684", "title": "EB viral genomes in epithelial nasopharyngeal carcinoma cells.", "content": "EB viral genomes in epithelial nasopharyngeal carcinoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353684"}
{"pmid": "4353687", "title": "Motor nerve conduction velocity and electromyogram in chronic lead poisoning.", "content": "Motor nerve conduction velocity and electromyogram in chronic lead poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353687"}
{"pmid": "4353688", "title": "Congenital hemihypertrophy with oligophrenia. Genetic and Dermatoglyphic data, muscle structural and ultrastructural aspects. (Report of a case).", "content": "Congenital hemihypertrophy with oligophrenia. Genetic and Dermatoglyphic data, muscle structural and ultrastructural aspects. (Report of a case).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353688"}
{"pmid": "4353693", "title": "Improved hemagglutination inhibition assay for mammary tumor virus antigen.", "content": "Improved hemagglutination inhibition assay for mammary tumor virus antigen. It is our experience that the use of sheep red blood cells pretreated with formaldehyde and pyruvaldehyde before sensitizing with viral antigen yields results that are comparable to that obtained by using the tannic acid method. The double aldehyde method provides the added advantage of being useful for assaying the viral antigen content in substances which contain high levels of interfering substances which would preclude the use of other assay methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353693"}
{"pmid": "4353692", "title": "Assay methods for Clostridium perfringens type A enterotoxin.", "content": "Assay methods for Clostridium perfringens type A enterotoxin. Enterotoxin produced by a sporulating culture of Clostridium perfringens type A NCTC 8798 was purified to a level of 3,500 mouse mean lethal doses per mg of nitrogen. High-titer sera were obtained from rabbits injected with enterotoxin and used to compare the sensitivity of serological tests and bioassays for C. perfringens enterotoxin. Reversed passive hemagglutination was by far the most sensitive test, followed by microslide diffusion, single gel diffusion and electroimmunodiffusion, guinea pig skin test, mouse test, and rabbit ileal loop test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353692"}
{"pmid": "4353695", "title": "Studies on the postnatal development of responses of hepatic histidase to endocrine control.", "content": "Studies on the postnatal development of responses of hepatic histidase to endocrine control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353695"}
{"pmid": "4353696", "title": "The role of phospholipids in TSH stimulation of adenylate cyclase in thyroid plasma membranes.", "content": "The role of phospholipids in TSH stimulation of adenylate cyclase in thyroid plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353696"}
{"pmid": "4353697", "title": "Evidence for a peptidic factor in spermatozoa inhibiting the ovarian maturation.", "content": "Evidence for a peptidic factor in spermatozoa inhibiting the ovarian maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353697"}
{"pmid": "4353698", "title": "The chemotactic effect of 5'-amido analogues of adenosine cycle 3',5'-monophosphate in the cellular slime moulds.", "content": "The chemotactic effect of 5'-amido analogues of adenosine cycle 3',5'-monophosphate in the cellular slime moulds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353698"}
{"pmid": "4353699", "title": "The role of the anion-binding site of transferrin in its interaction with the reticulocyte.", "content": "The role of the anion-binding site of transferrin in its interaction with the reticulocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353699"}
{"pmid": "4353700", "title": "The physical chemistry of hemes and hemopeptides. I. Physiochemical properties and reduction of chlorodeuterohemin in organic solvent.", "content": "The physical chemistry of hemes and hemopeptides. I. Physiochemical properties and reduction of chlorodeuterohemin in organic solvent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353700"}
{"pmid": "4353701", "title": "Distribution of glutamine hexosephosphate aminotransferase in rat tissues; changes with state of differentiation.", "content": "Distribution of glutamine hexosephosphate aminotransferase in rat tissues; changes with state of differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353701"}
{"pmid": "4353702", "title": "Phosphatidyldiglucosyl diglyceride from Streptococci and its relationship to other polar lipids.", "content": "Phosphatidyldiglucosyl diglyceride from Streptococci and its relationship to other polar lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353702"}
{"pmid": "4353703", "title": "Phospholipids of a moderately halophilic halotolerant bacterium. Isolation and identification of glucosylphosphatidylglycerol.", "content": "Phospholipids of a moderately halophilic halotolerant bacterium. Isolation and identification of glucosylphosphatidylglycerol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353703"}
{"pmid": "4353705", "title": "Synthesis in vivo of phospholipids of liver mitochondria and endoplasmic reticulum from glycerol and fatty acids.", "content": "Synthesis in vivo of phospholipids of liver mitochondria and endoplasmic reticulum from glycerol and fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353705"}
{"pmid": "4353706", "title": "The response of diphosphoinositide and triphosphoinostitide to perturbations of the adenylate energy charge in cells of Saccharomyces cerevisiae.", "content": "The response of diphosphoinositide and triphosphoinostitide to perturbations of the adenylate energy charge in cells of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353706"}
{"pmid": "4353707", "title": "The exchange of phospholipids between plasma lipoproteins and rapidly dividing human cells grown in tissue culture.", "content": "The exchange of phospholipids between plasma lipoproteins and rapidly dividing human cells grown in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353707"}
{"pmid": "4353708", "title": "A method for the determination of the initial rate of reaction of lecithin: cholesterol acyltransferase in human plasma.", "content": "A method for the determination of the initial rate of reaction of lecithin: cholesterol acyltransferase in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353708"}
{"pmid": "4353709", "title": "Uncoiling and protein cleavage of paramyxovirus nucleocapsid after incubation with ribosomes in vitro.", "content": "Uncoiling and protein cleavage of paramyxovirus nucleocapsid after incubation with ribosomes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353709"}
{"pmid": "4353710", "title": "Studies on bovine pancreatic deoxyribonuclease A. II. The effect of different bivalent metals on the specificity of degradation of DNA.", "content": "Studies on bovine pancreatic deoxyribonuclease A. II. The effect of different bivalent metals on the specificity of degradation of DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353710"}
{"pmid": "4353711", "title": "Gaucher-like cells and congenital dyserythropoietic anaemia, type II (HEMPAS).", "content": "Gaucher-like cells and congenital dyserythropoietic anaemia, type II (HEMPAS).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353711"}
{"pmid": "4353712", "title": "Effect of isopropyl methane sulphonate (IMS) on haemopoietic colony-forming cells.", "content": "Effect of isopropyl methane sulphonate (IMS) on haemopoietic colony-forming cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353712"}
{"pmid": "4353713", "title": "Considerations in the radiation therapy of Wilms' tumor.", "content": "Considerations in the radiation therapy of Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353713"}
{"pmid": "4353714", "title": "Treatment of Wilms' tumor and factors affecting prognosis.", "content": "Treatment of Wilms' tumor and factors affecting prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353714"}
{"pmid": "4353715", "title": "Wilms' tumor--an interdisciplinary treatment program with and without dactinomycin.", "content": "Wilms' tumor--an interdisciplinary treatment program with and without dactinomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353715"}
{"pmid": "4353716", "title": "Serial catecholamines in the radiation management of children with neuroblastoma.", "content": "Serial catecholamines in the radiation management of children with neuroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353716"}
{"pmid": "4353717", "title": "Some nonspecific morphological changes in neuromuscular diseases.", "content": "Some nonspecific morphological changes in neuromuscular diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353717"}
{"pmid": "4353718", "title": "Type 3 hyperlipoproteinaemia and sinking prebeta lipoprotein.", "content": "Type 3 hyperlipoproteinaemia and sinking prebeta lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353718"}
{"pmid": "4353719", "title": "Release factor regulating termination of complete protein in a eukaryotic organism.", "content": "Release factor regulating termination of complete protein in a eukaryotic organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353719"}
{"pmid": "4353721", "title": "Self-annealing of 4 S strands from replicating simian virus 40 DNA.", "content": "Self-annealing of 4 S strands from replicating simian virus 40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353721"}
{"pmid": "4353720", "title": "Association of polyadenylic acid with messenger RNA of vesicular stomatitis virus.", "content": "Association of polyadenylic acid with messenger RNA of vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353720"}
{"pmid": "4353722", "title": "The storage and release of transmitter substances from Helix neurones.", "content": "The storage and release of transmitter substances from Helix neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353722"}
{"pmid": "4353724", "title": "Renal vasodilation and the antinatriuretic effect of angiotensin in the rat.", "content": "Renal vasodilation and the antinatriuretic effect of angiotensin in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353724"}
{"pmid": "4353723", "title": "Effects of various secretagogues upon 42K and 22NA uptake during in vitro hormone release from the rat adenohypophysis.", "content": "Effects of various secretagogues upon 42K and 22NA uptake during in vitro hormone release from the rat adenohypophysis. 1. The in vitro uptake of (22)Na and (42)K was measured simultaneously in rat adenohypophyses during hormone release produced by several secretagogues and during inhibition of hormone release in Ca-free media.2. Intracellular adenohypophysial [Na(+)] and [K(+)] changed only slightly when the uptake changed. This would indicate that relative permeability changes were the primary effect of the treatments.3. The uptake of (42)K was increased by elevated external [K(+)], but was unaffected by the presence or absence of Ca(2+). Acid extracts of hypothalamus-stalk-median eminence or cerebellum also increased the (42)K uptake.4. The uptake of (22)Na or (24)Na was decreased by elevated [K(+)]. Uptake was increased in Ca-free Krebs-Ringer bicarbonate; but was unaltered when [K(+)] was concurrently increased.5. Neither purified growth hormone releasing hormone, synthetic lysine-vasopressin, dibutyryl cyclic AMP nor theophylline had an effect on the uptake of either K(+) or Na(+).6. The rapid uptake of (22)Na and its smaller volume of distribution compared to absolute measurements of intracellular [Na(+)] suggest that the plasma membrane of adenohypophysial cells is relatively impermeable to Na(+).7. We conclude that changes in the uptake of Na(+) and K(+) associated with hormone release are incidental to the release process.8. Hormone release produced by elevated external [K(+)] is most likely due to a non-specific increase in permeability of the cell membranes, facilitating Ca(2+) entry into the cytoplasm.9. The results suggest that the low resting transmembrane potentials of adenohypophysial cells may be due to their conjoint relatively high permeability to both K(+) and Ca(2+), rather than K(+) and Na(+).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353723"}
{"pmid": "4353725", "title": "Individualization of angiotensin receptors in smooth muscle cell membranes.", "content": "Individualization of angiotensin receptors in smooth muscle cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353725"}
{"pmid": "4353726", "title": "The effect of divalent cations on angiotensin stimulation of fluid transport by rat colon.", "content": "The effect of divalent cations on angiotensin stimulation of fluid transport by rat colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353726"}
{"pmid": "4353727", "title": "Evidence for two corticosteroid receptor mechanisms in the feedback control of corticotrophin secretion.", "content": "Evidence for two corticosteroid receptor mechanisms in the feedback control of corticotrophin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353727"}
{"pmid": "4353728", "title": "Mechanism of excitation of uterine smooth muscle. Changes in ionic fluxes induced by angiotensin.", "content": "Mechanism of excitation of uterine smooth muscle. Changes in ionic fluxes induced by angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353728"}
{"pmid": "4353729", "title": "The physiological role of prostaglandins in parturition.", "content": "The physiological role of prostaglandins in parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353729"}
{"pmid": "4353730", "title": "Effects of intrafollicular injection of hormones and drugs.", "content": "Effects of intrafollicular injection of hormones and drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353730"}
{"pmid": "4353731", "title": "Nature, role and control of the gonadotrophins.", "content": "Nature, role and control of the gonadotrophins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353731"}
{"pmid": "4353732", "title": "-Autoradiography of 10B compound distribution in tissue by use of superimposition technique.", "content": "-Autoradiography of 10B compound distribution in tissue by use of superimposition technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353732"}
{"pmid": "4353735", "title": "Hepatitis B antigenemia. Clinical implications.", "content": "Hepatitis B antigenemia. Clinical implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353735"}
{"pmid": "4353740", "title": "Pituitary and gonadal function in hypogonadotrophic hypogonadism.", "content": "Pituitary and gonadal function in hypogonadotrophic hypogonadism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353740"}
{"pmid": "4353742", "title": "The effect of dihydroergotamine on ACTH-stimulated lipolysis in rat adipocytes.", "content": "The effect of dihydroergotamine on ACTH-stimulated lipolysis in rat adipocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353742"}
{"pmid": "4353741", "title": "Hypothalamic-pituitary-adrenal function in patients with pituitary tumours.", "content": "Hypothalamic-pituitary-adrenal function in patients with pituitary tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353741"}
{"pmid": "4353743", "title": "Evidence for the internal feedback phenomenon in human subjects: effects of ACTH on plasma CRF.", "content": "Evidence for the internal feedback phenomenon in human subjects: effects of ACTH on plasma CRF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353743"}
{"pmid": "4353745", "title": "Oestriol conjugates in amniotic fluid. Qualitative and quantitative aspects, including preliminary studies in Rh isoimmunization.", "content": "Oestriol conjugates in amniotic fluid. Qualitative and quantitative aspects, including preliminary studies in Rh isoimmunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353745"}
{"pmid": "4353744", "title": "Differential action of parathyroid and thyroid hormones on effective intestinal absorption of calcium. In vivo studies with 47calcium in rats.", "content": "Differential action of parathyroid and thyroid hormones on effective intestinal absorption of calcium. In vivo studies with 47calcium in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353744"}
{"pmid": "4353747", "title": "Review of treatment of Méniére's syndrome.", "content": "Review of treatment of Méniére's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353747"}
{"pmid": "4353748", "title": "The effect of betahistine hydrochloride in Méniére's disease.", "content": "The effect of betahistine hydrochloride in Méniére's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353748"}
{"pmid": "4353749", "title": "The effect of Serc (betahistine hydrochloride) on the circulation of the inner ear in experimental animals.", "content": "The effect of Serc (betahistine hydrochloride) on the circulation of the inner ear in experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353749"}
{"pmid": "4353751", "title": "A study of the efficacy of betahistine in Méniére's syndrome.", "content": "A study of the efficacy of betahistine in Méniére's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353751"}
{"pmid": "4353750", "title": "Méniére's disease: subjective and objective evaluation of medical treatment with betahistine HCl.", "content": "Méniére's disease: subjective and objective evaluation of medical treatment with betahistine HCl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353750"}
{"pmid": "4353752", "title": "Factors influencing the cure rate in nephroblastoma. A review of 335 cases.", "content": "Factors influencing the cure rate in nephroblastoma. A review of 335 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353752"}
{"pmid": "4353755", "title": "Formation of the native structure of proteins: inferences from the kinetics of denaturation and renaturation.", "content": "Formation of the native structure of proteins: inferences from the kinetics of denaturation and renaturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353755"}
{"pmid": "4353756", "title": "Mechanisms in the chemical syntheses of polypeptides and polynucleotides.", "content": "Mechanisms in the chemical syntheses of polypeptides and polynucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353756"}
{"pmid": "4353757", "title": "The kinetics of transmitter release in myasthenia gravis. II. An electrophysiological analysis of the replenishment of transmitter stores.", "content": "The kinetics of transmitter release in myasthenia gravis. II. An electrophysiological analysis of the replenishment of transmitter stores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353757"}
{"pmid": "4353746", "title": "Inhibition of the noradrenaline-induced adenyl cyclase stimulation by augmented alpha-adrenergic response in subcutaneous adipose tissue from hypothyroid subjects.", "content": "Inhibition of the noradrenaline-induced adenyl cyclase stimulation by augmented alpha-adrenergic response in subcutaneous adipose tissue from hypothyroid subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353746"}
{"pmid": "4353763", "title": "Metabolic abnormalities in asthma--decreased urinary cycle AMP.", "content": "Metabolic abnormalities in asthma--decreased urinary cycle AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353763"}
{"pmid": "4353764", "title": "Adjuvant induced formation of lysophosphatides and their role in the immune response.", "content": "Adjuvant induced formation of lysophosphatides and their role in the immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353764"}
{"pmid": "4353765", "title": "The effects of adjuvants and stress on the production of IgE antibody in rats.", "content": "The effects of adjuvants and stress on the production of IgE antibody in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353765"}
{"pmid": "4353766", "title": "Studies on surface antigens of mammalian cells.", "content": "Studies on surface antigens of mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353766"}
{"pmid": "4353767", "title": "The relationship between the viruses causing hepatitis and autoimmunity in liver disease.", "content": "The relationship between the viruses causing hepatitis and autoimmunity in liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353767"}
{"pmid": "4353768", "title": "Studies on the mechanism of T lymphocyte-mediated cytolysis.", "content": "Studies on the mechanism of T lymphocyte-mediated cytolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353768"}
{"pmid": "4353769", "title": "The mechanism of action of macrophage migration inhibitory factor (MIF).", "content": "The mechanism of action of macrophage migration inhibitory factor (MIF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353769"}
{"pmid": "4353771", "title": "Cerebrocortical adenyl cyclase activity following neonatal thyroid hormone deficiency.", "content": "Cerebrocortical adenyl cyclase activity following neonatal thyroid hormone deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353771"}
{"pmid": "4353770", "title": "Immunological properties of carbohydrate and protein fractions of Timothy grass pollens.", "content": "Immunological properties of carbohydrate and protein fractions of Timothy grass pollens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353770"}
{"pmid": "4353772", "title": "Enhanced effects of prostaglandin E1 and dibutyryl cyclic AMP upon human lymphocytes in the presence of cortisol.", "content": "Enhanced effects of prostaglandin E1 and dibutyryl cyclic AMP upon human lymphocytes in the presence of cortisol. The combined effects of cortisol and agents acting through a cyclic AMP-mediated mechanism have been studied in cultures of highly purified human peripheral lymphocytes. Incubation with prostaglandin E(1) (PGE(1)), dibutyryl cyclic AMP, or cortisol results in a concentration-dependent inhibition of [(3)H]-thymidine incorporation by both unstimulated and phytohemagglutinin (PHA)-stimulated lymphocytes, and PHA-induced morphologic transformation is prevented. When cortisol and PGE(1) (or dibutyryl cyclic AMP) are added together to lymphocyte cultures, enhanced inhibitory effects are observed. Incubation of unstimulated or PHA-stimulated lymphocytes with PGE(1) results in an elevation of intracellular cyclic AMP levels within 20 min. The concentration of cyclic AMP gradually returns to base-line levels over a 1-6 h period of time. Cortisol alone does not significantly alter cyclic AMP concentrations. However, incubation with PGE(1) in the presence of cortisol results in a greater stimulation of intracellular cyclic AMP levels than that observed with PGE(1) alone. These findings suggest that cortisol may act synergistically with PGE(1) to elevate lymphocyte cyclic AMP levels and to regulate [(3)H]thymidine incorporation and transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353772"}
{"pmid": "4353773", "title": "Mechanism of the hypolipemic effect of clofibrate in postabsorptive man.", "content": "Mechanism of the hypolipemic effect of clofibrate in postabsorptive man. Splanchnic metabolism of triglycerides and other major substrates was studied in the postabsorptive state in normotriglyceridemic and hypertriglyceridemic human subjects who received (1/2) g of clofibrate four times daily for 3 wk. Transport in blood plasma of triglycerides produced in the splanchnic region was quantified by three methods: (a) measurement of the transsplanchnic gradient of (14)C-labeled triglycerides during constant intravenous infusion of [1- (14)C] palmitate (b) chemical measurement of the transplanchnic gradient in concentration of triglycerides of very low density lipoproteins; and (c) determination of clearance of (14)C-labeled triglycerides in extrasplanchnic tissues. The first method measures only triglycerides derived from free fatty acids and the last two measure total splanchnic production. In hypertriglyceridemic subjects treated with clofibrate, average rates of total splanchnic production of triglycerides and production from free fatty acids were the same as those of comparable untreated subjects despite a consistent fall in plasma triglyceride levels. The hypotriglyceridemic effect of the drug was therefore accompanied by improved disposal of triglycerides in extrasplanchnic tissues. In treated normotriglyceridemic subjects, unlike their untreated counterparts, total splanchnic production was significantly higher than production from free fatty acids. Failure of clofibrate to reduce triglyceride levels in normotriglyceridemic subjects may have been related to increased total splanchnic production, coupled with improved extrasplanchnic disposal. Systemic transport and net splanchnic uptake of free fatty acids were similar in treated and control subjects but the fraction of [1-(14)C]palmitate converted to acetoacetate in splanchnic tissues was significantly higher in treated subjects. Net splanchnic extraction of plasma amino acids that enter the glucogenic pathway via pyruvate was increased in treated subjects and their arterial concentrations were reduced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353773"}
{"pmid": "4353774", "title": "Hypoxanthine-guanine phosphoribosyltransferase variant associated with accelerated purine synthesis.", "content": "Hypoxanthine-guanine phosphoribosyltransferase variant associated with accelerated purine synthesis. We have previously described a 14-yr-old boy with hyperuricemia, renal failure, and accelerated purine production resistant in vivo and in vitro to purine analogs. This patient demonstrated normal red cell hypoxanthine-guanine phosphoribosyltransferase (HPRT) heat stability, electrophoresis at high pH, and activity at standard substrate levels. In the present report an abnormal HPRT enzyme was demonstrated by enzyme kinetic study with phosphoribosylpyrophosphate (PRPP) as the variable substrate and inhibitory studies with sodium fluoride. Apparently normal HPRT activity in a patient with hyperuricemia and gout does not exclude a functionally significant HPRT mutation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353774"}
{"pmid": "4353777", "title": "Cyclic AMP and sodium transport. Quantitative and temporal relationships in toad urinary bladder.", "content": "Cyclic AMP and sodium transport. Quantitative and temporal relationships in toad urinary bladder. The effects of oxytocin upon tissue cAMP content and short-circuit current (SCC) were measured in the urinary bladder of the toad, Bufo marinus. Tissue cAMP levels doubled before any increment in SCC was observed, the two hormone responses were quantitatively related, and a threshold level for an effect of cAMP upon sodium transport was demonstrated. The period of time over which cAMP levels continued to rise after the threshold level had been attained seemed invariant with hormone concentration. The rate at which cAMP levels rose increased with hormone concentration yielding hormone concentration-dependent maximal levels. The decay of cAMP levels was delayed when sodium influx was curtailed, suggesting a sodium-regulatory effect upon tissue cAMP levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353777"}
{"pmid": "4353775", "title": "Maturation of responsiveness to cardioactive drugs. Differential effects of acetylcholine, norepinephrine, theophylline, tyramine, glucagon, and dibutyryl cyclic AMP on atrial rate in hearts of fetal mice.", "content": "Maturation of responsiveness to cardioactive drugs. Differential effects of acetylcholine, norepinephrine, theophylline, tyramine, glucagon, and dibutyryl cyclic AMP on atrial rate in hearts of fetal mice. Freshly isolated hearts of fetal mice of gestational ages ranging between 12 and 22 days (term) were exposed to several concentrations of a variety of chronotropic agents. Acetylcholine (10(-4)-10(-2) M) caused marked bradycardia in all hearts, even after only 12-14 days' gestation (i.e., even before cardiac innervation had occurred), and the intensity of the response increased steadily with advancing age throughout gestation. Responsiveness to norepinephrine was present but minimal at 12-14 days, so that mean atrial rate rose by < 10% with a maximal concentration of the drug (10(-5) M); responsiveness became more marked by 15-16 days (just after the time atrial innervation is thought to begin) and still greater effects appeared just before term. Glucagon had no effect in hearts of < 17 days' gestational age, but caused tachycardia thereafter, indicating that cardiac responsiveness to glucagon differentiates later than does responsiveness to norepinephrine. Responses to theophyl-line in 12-14 day hearts exceeded those to norepinephrine, indicating that the drug can affect heart rate independently of its ability to cause release of endogenous catecholamines. In contrast, tyramine caused no response until 21-22 days, well after the time the beta-receptor has differentiated and after innervation is fairly well developed, suggesting that the drug's primary sympathomimetic effect is indirect rather than direct. Dibutyryl cyclic AMP did not cause tachycardia at any fetal age. It is concluded that maturation of responsiveness of the mouse heart to cardioactive drugs develops in specific patterns for different agents. The identification of differential patterns of maturation for various drugs may provide valuable means for characterizing the differentiation of specific receptors and for investigating possible mechanisms of action of the drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353775"}
{"pmid": "4353776", "title": "Circadian rhythm of plasma aldosterone concentration in patients with primary aldosteronism.", "content": "Circadian rhythm of plasma aldosterone concentration in patients with primary aldosteronism. Plasma aldosterone, cortisol, and renin activity were measured in nine recumbent patients with hyperaldosteronism, including seven with adenomas, one with idiopathic hyperplasia, and one with glucocorticoid suppressible hyperplasia. All had peak values of plasma aldosterone concentration from 3 a.m. to noon and lowest values at 6 p.m. or midnight. This rhythm was similar to the circadian pattern of plasma cortisol in the same patients. When these data were normalized to eliminate the wide variation in ranges of plasma aldosterone and cortisol between individuals, there was an excellent correlation (r = + 0.87, P < 0.005) between the two hormones. In contrast, plasma aldosterone concentrations did not correlate with plasma renin activity before or after normalization of data. Short term suppression of ACTH by administration of dexamethasone eliminated the circadian variation of plasma aldosterone in both patients with hyperplasia and in four of five patients with adenomas, while it markedly altered the rhythm in the fifth. Similar doses of dexamethasone were administered to four normal subjects and did not flatten the circadian rhythm of plasma aldosterone. These data suggest that patients with primary aldosteronism have a circadian rhythm of plasma aldosterone mediated by changes in ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353776"}
{"pmid": "4353782", "title": "Infection with herpes-simplex viruses 1 and 2. II.", "content": "Infection with herpes-simplex viruses 1 and 2. II. Herpes-simplex virus 1 (HSV1) and 2 can cause recurrent infection in man and in nonhuman species localized on a specific area of the body, such as face, cornea, or genitals.  The origin of the virus responsible for a recurrent infection is not usually apparent.  Some possible sources of virus can be exogenous infection, endogenous infection from another site of the body, chronic, continuous viral multiplication around the site of involvement, and persistence of the virus at the site of the recurrent infection.  No definite information is yet available regarding the mechanism by which HSV1 or HSV2 persists and it is triggered to multiply, or regarding the cells that harbor the virus.  It is possible that frequent or constant antigenic stimulation occurs in at least some cases of recurrent herpetic infections.  The role of antibodies and of interferon in host resistance to HSV remains to be elucidated.  Several recent studies have shown the association of more than a dozen herpes viruses with cancer in man and various animals; for example with limphoma, and with squamous cell carcinoma of the lip and cancer of the cervix.  Genital HSV infections and cervical cancer were first linked when it was noted that women with genital herpes had a high frequency of cervical dysplasia and cancer.  The results of new seroepidemiologic studies on this subject are still difficult to evaluate.  Inocculation of HSV2 in laboratory animals has resulted in sarcomas, but it has never been possible to prove that the virus caused the tumors, since no HSV antigens could be detected in the tumors.  However, herpesvirus antigens have been demonstrated by immunofluorescent technics in exfoliated cervical cells obtained from women with dysplasia, carcinoma in situ, and invasive carcinoma.  In the absence of other kinds of data, it is difficult to rule out the possibility that the presence of HSV2 or of antigens is not an independent event unrelated to the cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353782"}
{"pmid": "4353784", "title": "Potassium, angiotensin and the dual control of aldosterone secretion.", "content": "Potassium, angiotensin and the dual control of aldosterone secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353784"}
{"pmid": "4353783", "title": "The chemotherapy of viral infections.", "content": "The chemotherapy of viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353783"}
{"pmid": "4353785", "title": "Endocrine complications of malignancy.", "content": "Endocrine complications of malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353785"}
{"pmid": "4353786", "title": "Clinical and epidemiologic clues to the diagnosis of respiratory infections.", "content": "Clinical and epidemiologic clues to the diagnosis of respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353786"}
{"pmid": "4353788", "title": "Herpes viruses and cancer.", "content": "Herpes viruses and cancer. Type 2 herpes simplex virus belongs to the herpes virus group, members of which have been shown to cause cancer in animals -- kidney cancer in frogs, lymphoid cancer in chickens and rabbits, and lung cancer in sheep.  A herpes virus causes Burkett's lymphoma in humans;  another causes nasopharyngeal cancer in humans.  Herpes simplex viruses are common in humans in cervical and vaginal sores in women and in the genital tract in men (an estimated 15% of men older than 15).  It is transmitted venereally.  Type 2 herpes simplex virus has been epidemiologically associated with cervical cancer.  It has been found in prostate cancer cells.  In a hybridization experiment with DNA from cervical cancer cells, DNA from type 2 herpes simplex virus was found, but 60% of the viral DNA molecule was missing.  In the chicken lymphoid cancer caused by a herpes virus, live virus vaccine eradicated the disease.  This suggests that, if type 2 herpes simplex virus is found to cause cervical cancer, a vaccination cure can be developed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353788"}
{"pmid": "4353791", "title": "Immunohistological, microscopical and neurochemical studies on encephalitides. 7. Subacute sclerosing panencephalitis. Susceptibility of dogs to the virus, and characterization of host response.", "content": "Immunohistological, microscopical and neurochemical studies on encephalitides. 7. Subacute sclerosing panencephalitis. Susceptibility of dogs to the virus, and characterization of host response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353791"}
{"pmid": "4353792", "title": "Differential sensitivity of virulent and attenuated strains of type 1 poliovirus to polyethylene glycol as a possible new genetic marker.", "content": "Differential sensitivity of virulent and attenuated strains of type 1 poliovirus to polyethylene glycol as a possible new genetic marker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353792"}
{"pmid": "4353794", "title": "Haemadsorption-negative assay of rubella virus in baby hamster kidney cells.", "content": "Haemadsorption-negative assay of rubella virus in baby hamster kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353794"}
{"pmid": "4353793", "title": "Differential growth of MHV (PRI) and MHV (C3H) in genetically resistant C3H mice rendered susceptible by eperythrozoon infection.", "content": "Differential growth of MHV (PRI) and MHV (C3H) in genetically resistant C3H mice rendered susceptible by eperythrozoon infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353793"}
{"pmid": "4353795", "title": "The isolation and partial characterization of a herpesvirus from a case of bovine metritis.", "content": "The isolation and partial characterization of a herpesvirus from a case of bovine metritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353795"}
{"pmid": "4353796", "title": "Ultrastructural examination of phytohemagglutinin stimulated lymphocytes infected with vesicular stomatitis virus.", "content": "Ultrastructural examination of phytohemagglutinin stimulated lymphocytes infected with vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353796"}
{"pmid": "4353797", "title": "Genetic studies of respiratory syncytial virus temperature-sensitive mutants.", "content": "Genetic studies of respiratory syncytial virus temperature-sensitive mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353797"}
{"pmid": "4353798", "title": "Electron microscopic studies of respiratory syncytial temperature-sensitive mutants.", "content": "Electron microscopic studies of respiratory syncytial temperature-sensitive mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353798"}
{"pmid": "4353799", "title": "Multiplication of the virus of epizootic haemorrhagic disease of deer in culicoides species (Diptera, Ceratopogonidae).", "content": "Multiplication of the virus of epizootic haemorrhagic disease of deer in culicoides species (Diptera, Ceratopogonidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353799"}
{"pmid": "4353800", "title": "Elevation of the intracellular levels of cyclic adenosine monophosphate during in vitro infection of transmissible gastroenteritis virus. Brief report.", "content": "Elevation of the intracellular levels of cyclic adenosine monophosphate during in vitro infection of transmissible gastroenteritis virus. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353800"}
{"pmid": "4353801", "title": "Location of Rous sarcoma viral structural polypeptides on the virion surface. Brief report.", "content": "Location of Rous sarcoma viral structural polypeptides on the virion surface. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353801"}
{"pmid": "4353802", "title": "Effects of hycanthone on rapidly proliferating cells.", "content": "Effects of hycanthone on rapidly proliferating cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353802"}
{"pmid": "4353804", "title": "Effects of quinidine on some reactions and ion translocations catalyzed by the Na+, K+ -ATPase complex.", "content": "Effects of quinidine on some reactions and ion translocations catalyzed by the Na+, K+ -ATPase complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353804"}
{"pmid": "4353803", "title": "Preservation of structural integrity of liver lysosomes and membrane-stabilizing action of anti-inflammatory drugs, catecholamines and cyclic adenosine monophosphate in isotonic salt media.", "content": "Preservation of structural integrity of liver lysosomes and membrane-stabilizing action of anti-inflammatory drugs, catecholamines and cyclic adenosine monophosphate in isotonic salt media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353803"}
{"pmid": "4353805", "title": "Leukokinin-forming system in the ascitic fluid of a murine mastocytoma.", "content": "Leukokinin-forming system in the ascitic fluid of a murine mastocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353805"}
{"pmid": "4353806", "title": "Carbohydrate metabolism in the plasmodium of the myxomycete Physarum flavicomum.", "content": "Carbohydrate metabolism in the plasmodium of the myxomycete Physarum flavicomum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353806"}
{"pmid": "4353809", "title": "Isolation and some characteristics of liver plasma membranes from rainbow trout.", "content": "Isolation and some characteristics of liver plasma membranes from rainbow trout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353809"}
{"pmid": "4353808", "title": "Plasma enzyme levels and erythrocyte G6P-DH activity in ducks and chicken.", "content": "Plasma enzyme levels and erythrocyte G6P-DH activity in ducks and chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353808"}
{"pmid": "4353810", "title": "Intermediary metabolism in Dicrocoelium dendriticum (Trematoda).", "content": "Intermediary metabolism in Dicrocoelium dendriticum (Trematoda).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353810"}
{"pmid": "4353811", "title": "Metabolism in porifera. I. Some studies on the biosynthesis of fatty acids, sterols and bromo-compounds by the sponge Verongia aerophoba.", "content": "Metabolism in porifera. I. Some studies on the biosynthesis of fatty acids, sterols and bromo-compounds by the sponge Verongia aerophoba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353811"}
{"pmid": "4353812", "title": "Characterization of ubiquinone from vegetative amoebae and mature sorocarps of the cellular slime mold, Dictyostelium discoideum.", "content": "Characterization of ubiquinone from vegetative amoebae and mature sorocarps of the cellular slime mold, Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353812"}
{"pmid": "4353813", "title": "Identification of astaxanthin in Scottish salmon.", "content": "Identification of astaxanthin in Scottish salmon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353813"}
{"pmid": "4353814", "title": "The management of oral ulceration.", "content": "The management of oral ulceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353814"}
{"pmid": "4353815", "title": "Growth hormone regulation and hypothalamic-pituitary-adrenal function in anorexia nervosa.", "content": "Growth hormone regulation and hypothalamic-pituitary-adrenal function in anorexia nervosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353815"}
{"pmid": "4353818", "title": "Characterization of an avian reovirus isolated in Queensland.", "content": "Characterization of an avian reovirus isolated in Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353818"}
{"pmid": "4353819", "title": "Cytostatic elimination of syngeneic rat tumor cells in vitro by nonspecifically activated macrophages.", "content": "Cytostatic elimination of syngeneic rat tumor cells in vitro by nonspecifically activated macrophages. Syngeneic tumor cell lines induced in inbred DA rats by polyoma virus, dimethylbenzanthracene, or methylcholanthrene were interacted in vitro with syngeneic effector cells. Glycogen-induced peritoneal exudate cells, predominantly polymorphonuclear leukocytes, and proteose peptone-induced peritoneal cells, principally macrophages, were the effector cells employed. Activated, nonimmune macrophages or exudative polymorphonuclear leukocytes produced pronounced morphological changes in syngeneic tumor cells as evidenced by a substantial reduction in tumor cell numbers and appearance of shrunken cells, even though there was no increase in cell debris. Polymorphonuclear leukocytes exerted a generally similar but quantitatively much diminished effect. These effector cells constantly produced a decrease in the incorporation by tumor cells of DNA precursors such as [(3)H]thymidine and of RNA precursors such as [(3)H]uridine. In this regard, the effector cells were quite refractory to high doses of X-irradiation. Interaction of target cells with activated, nonimmune macrophages yielded low but consistent signs of cytotoxicity, whereas polymorphonuclear leukocytes gave no such effects. Elimination of functional macrophages by silica, an agent specifically toxic for macrophages, resulted in unrestricted tumor cell proliferation despite continued generation of cytotoxicity. Accordingly, cytostatic mechanisms appear to play a predominant role in the elimination of tumor cells by nonimmune phagocytes. Evidence from a variety of experimental approaches suggest that the cytostatic effect is dependent on cell-to-cell contact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353819"}
{"pmid": "4353822", "title": "Stimulation of glucose-6-phosphatase activity in the mucosal cells of the mouse intestine.", "content": "Stimulation of glucose-6-phosphatase activity in the mucosal cells of the mouse intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353822"}
{"pmid": "4353820", "title": "Latent herpes simplex virus in the central nervous system of rabbits and mice.", "content": "Latent herpes simplex virus in the central nervous system of rabbits and mice. Herpes simplex virus (HSV) type 1 induces a long-standing latent infection in the central nervous system of mice and rabbits. The infection was extablished in the brain stems of rabbits after corneal inoculation of the virus, and in the spinal cords of mice after rear footpad infection. In these animals, infectious virus could not be recovered by direct isolation from tissues; it was detected only after the tissues were maintained as organ cultures in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353820"}
{"pmid": "4353823", "title": "Ultrastructural comparison of transformed human cells and their normal counterparts at various passage levels.", "content": "Ultrastructural comparison of transformed human cells and their normal counterparts at various passage levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353823"}
{"pmid": "4353821", "title": "A characterization of nucleoside diphosphatase in the onion root tip.", "content": "A characterization of nucleoside diphosphatase in the onion root tip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353821"}
{"pmid": "4353825", "title": "Infection with herpes-simplex viruses 1 and 2. 1.", "content": "Infection with herpes-simplex viruses 1 and 2. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353825"}
{"pmid": "4353826", "title": "Technical problems with agarose-hormone linkage.", "content": "Technical problems with agarose-hormone linkage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353826"}
{"pmid": "4353827", "title": "The male as a reservoir of infection with cytomegalovirus, herpes and mycoplasma.", "content": "The male as a reservoir of infection with cytomegalovirus, herpes and mycoplasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353827"}
{"pmid": "4353829", "title": "Sleep learning and progressive blurring of perception during sleep.", "content": "Sleep learning and progressive blurring of perception during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353829"}
{"pmid": "4353828", "title": "Primary visual experience and secondary cognitive elaboration in stage REM: a modest confirmation and an extension.", "content": "Primary visual experience and secondary cognitive elaboration in stage REM: a modest confirmation and an extension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353828"}
{"pmid": "4353830", "title": "Actions of glucagon and dibutyryl cyclic 3',5'-AMP on chronotropic responses to vagal stimulation and acetylcholine.", "content": "Actions of glucagon and dibutyryl cyclic 3',5'-AMP on chronotropic responses to vagal stimulation and acetylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353830"}
{"pmid": "4353831", "title": "Localization of the cyclic AMP system in the arterial wall.", "content": "Localization of the cyclic AMP system in the arterial wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353831"}
{"pmid": "4353832", "title": "The morphological consequences and the significance of cytomegalovirus infection in renal transplant patients.", "content": "The morphological consequences and the significance of cytomegalovirus infection in renal transplant patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353832"}
{"pmid": "4353833", "title": "A method for inducing unilateral silicosis in rabbits by an injection technique with some observations on lung clearance and quantitative evaluation of experimental silicosis.", "content": "A method for inducing unilateral silicosis in rabbits by an injection technique with some observations on lung clearance and quantitative evaluation of experimental silicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353833"}
{"pmid": "4353834", "title": "Early effects of quartz and titanium dioxide dust on pulmonary function and tissue. An experimental study on rabbits.", "content": "Early effects of quartz and titanium dioxide dust on pulmonary function and tissue. An experimental study on rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353834"}
{"pmid": "4353839", "title": "The isolation and transmission of the virus of infectious bovine rhinotracheitis-infectious pustular vulvo-vaginitis.", "content": "The isolation and transmission of the virus of infectious bovine rhinotracheitis-infectious pustular vulvo-vaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353839"}
{"pmid": "4353842", "title": "Benign mixed mesodermal tumors of the uterus: a histogenetic study.", "content": "Benign mixed mesodermal tumors of the uterus: a histogenetic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353842"}
{"pmid": "4353840", "title": "Diagnosis of mixed infections with myxovirus influenzae A equi 2 and herpes virus equi 1 among Danish stud horses.", "content": "Diagnosis of mixed infections with myxovirus influenzae A equi 2 and herpes virus equi 1 among Danish stud horses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353840"}
{"pmid": "4353841", "title": "The role of the platelet membrane in platelet function. I. Blood coagulation.", "content": "The role of the platelet membrane in platelet function. I. Blood coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353841"}
{"pmid": "4353844", "title": "Antacids before obstetric anaesthesia. A clinical evaluation of the effectiveness of mist. magnesium trisilicate BPC.", "content": "Antacids before obstetric anaesthesia. A clinical evaluation of the effectiveness of mist. magnesium trisilicate BPC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353844"}
{"pmid": "4353843", "title": "Agar plate dilution method for routine antibiotic susceptibility testing in a hospital laboratory.", "content": "Agar plate dilution method for routine antibiotic susceptibility testing in a hospital laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353843"}
{"pmid": "4353845", "title": "The locus of pathogenicity of asbestos dust: a theory.", "content": "The locus of pathogenicity of asbestos dust: a theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353845"}
{"pmid": "4353847", "title": "Terminal innervation ratio in neuromuscular disease. II. Disorders of lower motor neuron, peripheral nerve, and muscle.", "content": "Terminal innervation ratio in neuromuscular disease. II. Disorders of lower motor neuron, peripheral nerve, and muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353847"}
{"pmid": "4353846", "title": "Terminal innervation ratio in neuromuscular disease. I. Methods and controls.", "content": "Terminal innervation ratio in neuromuscular disease. I. Methods and controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353846"}
{"pmid": "4353848", "title": "Herpesvirus hominis encephalitis. Virus isolation from brain biopsy in seven patients and results of therapy.", "content": "Herpesvirus hominis encephalitis. Virus isolation from brain biopsy in seven patients and results of therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353848"}
{"pmid": "4353838", "title": "Glomus jugulare tumors: effect of irradiation.", "content": "Glomus jugulare tumors: effect of irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353838"}
{"pmid": "4353850", "title": "Enhanced release of insulin by prostaglandins in isolated pancreatic islets.", "content": "Enhanced release of insulin by prostaglandins in isolated pancreatic islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353850"}
{"pmid": "4353851", "title": "Neuromuscular junction defect in diabetes.", "content": "Neuromuscular junction defect in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353851"}
{"pmid": "4353852", "title": "Protein synthesis in the rat anterior pituitary. 3. The fate of total protein, prolactin and growth hormone labeled in an in vitro incubation.", "content": "Protein synthesis in the rat anterior pituitary. 3. The fate of total protein, prolactin and growth hormone labeled in an in vitro incubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353852"}
{"pmid": "4353853", "title": "Estrogen receptor in a prolactin secreting pituitary tumor (MtTW5).", "content": "Estrogen receptor in a prolactin secreting pituitary tumor (MtTW5).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353853"}
{"pmid": "4353854", "title": "Electrically stimulated ACTH release in pharmacologically blocked rats.", "content": "Electrically stimulated ACTH release in pharmacologically blocked rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353854"}
{"pmid": "4353855", "title": "An increase of thyroid hormone secretion in response to excess iodide in rats treated with thyroxine.", "content": "An increase of thyroid hormone secretion in response to excess iodide in rats treated with thyroxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353855"}
{"pmid": "4353856", "title": "Role of microtubules in basal and stimulated release of growth hormone and prolactin in rat adenohypophysis in vitro.", "content": "Role of microtubules in basal and stimulated release of growth hormone and prolactin in rat adenohypophysis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353856"}
{"pmid": "4353858", "title": "Corticosteroidogenesis and its relation to ACTH dependence of mitochondrial components.", "content": "Corticosteroidogenesis and its relation to ACTH dependence of mitochondrial components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353858"}
{"pmid": "4353857", "title": "Influence of alpha- and beta-subunits on the kinetics of formation and activity of native and hybrid molecules of LH and human chorionic gonadotropin.", "content": "Influence of alpha- and beta-subunits on the kinetics of formation and activity of native and hybrid molecules of LH and human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353857"}
{"pmid": "4353861", "title": "The toxicology of dieldrin (HEOD). I. Long-term oral toxicity studies in mice.", "content": "The toxicology of dieldrin (HEOD). I. Long-term oral toxicity studies in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353861"}
{"pmid": "4353862", "title": "Metabolism of Aflatoxin B1 by the guinea-pig.", "content": "Metabolism of Aflatoxin B1 by the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353862"}
{"pmid": "4353863", "title": "Pulmonary adenomatosis in guinea pigs exposed to coal dust inhalation.", "content": "Pulmonary adenomatosis in guinea pigs exposed to coal dust inhalation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353863"}
{"pmid": "4353864", "title": "Hepatoblastoma in children.", "content": "Hepatoblastoma in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353864"}
{"pmid": "4353865", "title": "An experimental Wilms' tumor suitable for therapeutic and biologic studies. II. The inhibition of renal compensatory hypertrophy by a transplantable tumor.", "content": "An experimental Wilms' tumor suitable for therapeutic and biologic studies. II. The inhibition of renal compensatory hypertrophy by a transplantable tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353865"}
{"pmid": "4353849", "title": "The use of chronic catheterization techniques in foetal sheep.", "content": "The use of chronic catheterization techniques in foetal sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353849"}
{"pmid": "4353867", "title": "The effects of gamma irradiation on the structure and reactivity of native and cross-linked collagen fibres.", "content": "The effects of gamma irradiation on the structure and reactivity of native and cross-linked collagen fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353867"}
{"pmid": "4353868", "title": "Characterization of invertase activity from cariogenic Streptococcus mutans.", "content": "Characterization of invertase activity from cariogenic Streptococcus mutans. Invertase activity from Streptococcus mutans GS-5 has been partially purified and shown to possess beta-fructofuranosidase specificity. The enzyme has a broad pH optimum between pH 5.5 and 7.5 and exhibits maximal activity at 37 C. Fructose, but not the glucose analogue alpha-methyl-d-glucoside, acts as a competitive inhibitor of the enzyme. None of the common glycolytic intermediates or adenine nucleotides had any significant effect on enzyme activity. A molecular weight of approximately 47,000 was estimated for the enzyme. The enzyme does not appear to be catabolically repressed by glucose nor inducible by sucrose. Higher specific activities of the enzyme are observed in fructose or glucose-grown cells compared to sucrose-grown cells. These results are discussed in terms of the regulation of invertase activity in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353868"}
{"pmid": "4353869", "title": "Physiological effects of menaquinone deficiency in Bacillus subtilis.", "content": "Physiological effects of menaquinone deficiency in Bacillus subtilis. Several aspects of the respiratory physiology of a mutant of Bacillus subtilis deficient in menaquinone-7 (MK-7) and in cytochromes were investigated. The mutant, an aromatic amino acid auxotroph blocked at dehydroshikimate reductase, is unable to synthesize MK-7 unless grown in the presence of the common aromatic amino acid intermediate, shikimate. The inability to synthesize MK-7 prevents the mutant from expressing the normal postexponentialphase cytochrome phenotype. When grown in the presence of shikimate, normal levels of these electron transport components are formed. It was found that the intracellular concentration of MK-7 could be predictably regulated by growing the cells with known concentrations of exogenous shikimate. When the mutant was grown under conditions where MK-7 biosynthesis was severely limited, there was a decrease in oxygen uptake and in membrane-associated reduced nicotinamide adenine dinucleotide (NADH) oxidase and succinate oxidase activity. NADH oxidase, but not succinoxidase, could be restored in membrane preparations by the addition of menadione to the reaction mixture. Reduced-minus-oxidized cytochrome difference spectra indicate that an MK-7 deficiency limits electron flow through the cytochrome chain. Furthermore, oxidation-reduction patterns suggest that MK-7 functions between the primary dehydrogenases and the cytochromes. Although the mutant is asporogenous when grown under conditions where MK-7 biosynthesis is limited, the inability to sporulate does not appear to result from lesions in the electron transport system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353869"}
{"pmid": "4353870", "title": "Isolation of a mutant of Escherichia coli defective in cytosine-specific deoxyribonucleic acid methylase activity and in partial protection of bacteriophage lambda against restriction by cells containing the N-3 drug-resistance factor.", "content": "Isolation of a mutant of Escherichia coli defective in cytosine-specific deoxyribonucleic acid methylase activity and in partial protection of bacteriophage lambda against restriction by cells containing the N-3 drug-resistance factor. A mutant (designated mec(-)) of Escherichia coli F(+) 100 endo I(-)su(+) r(K) (-)m(K) (+) has been isolated which is defective in cytosine-specific deoxyribonucleic acid (DNA) methylase activity. The DNA of this mutant, as well as the DNA of phages lambda and fd propagated in it, is virtually devoid of 5-methyl-cytosine (MeC); in contrast, the mutation has no significant effect on the level of N(6)-methyladenine in DNA. Phage lambda grown on the mec(-) mutant is more strongly restricted by N-3-containing cells than is lambda grown on the mec(+) parent. These results suggest that methylation of certain cytosine residues by the E. coli K-12 enzyme partially protects lambda DNA from either the N-3 restriction nuclease or against secondary degradation subsequent to N-3-specific degradation. Analysis of the MeC level in viral and cellular DNA obtained from mec(+), mec(+) (m(N3) (+)), and mec(-) (m(N3) (+)) strains has led to the conclusion that the R-factor controlled DNA-cytosine methylase may be capable of methylating a sequence(s) which is a substrate for the K-12 enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353870"}
{"pmid": "4353872", "title": "Studies on mitochondria membrane proteins in Saccharomyces cerevisiae under different degrees of glucose repression.", "content": "Studies on mitochondria membrane proteins in Saccharomyces cerevisiae under different degrees of glucose repression. Mitochondrial membrane proteins synthesized in vivo in the presence of cycloheximide were analyzed on electrofocusing polyacrylamide gels. Five of the six protein bands observed have their isoelectric points below pH 7. The six proteins are not synthesized when both cycloheximide and chloramphenicol are present, and they are absent in a petite mutant lacking mitochondrial deoxyribonucleic acid (DNA), leading to the conclusion that the proteins are synthesized on mitochondrial ribosomes. By labeling cells of Saccharomyces cerevisiae cultivated in a chemostat under different degrees of glucose limitation, the effect of glucose repression on the synthesis of the mitochondrial membrane proteins was determined. Two of the protein bands showed a relatively reduced synthesis under the strongest glucose repression tested. The specific activity of the cytochrome oxidase and the percentage of mitochondrial DNA in the total DNA were found to be influenced at a lower level of glucose repression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353872"}
{"pmid": "4353871", "title": "Effects of ethylenediaminetetraacetate and chloramphenicol on mitochondrial activity and morphogenesis in Mucor rouxii.", "content": "Effects of ethylenediaminetetraacetate and chloramphenicol on mitochondrial activity and morphogenesis in Mucor rouxii. The present study demonstrates the importance of mitochondrial activities in controlling Mucor rouxii morphogenesis. The respiratory capacity of the spores of this facultatively anaerobic, dimorphic fungus becomes repressed if germination and growth take place in the absence of oxygen. The level of activity of mitochondrial enzymes such as cytochrome oxidase and malate dehydrogenase is lower in the anaerobic yeastlike cells than it is in ungerminated spores and in aerobic hyphae, but the reverse is true for glycolytic enzymes such as pyruvate kinase and alcohol dehydrogenase. Following exposure to air, yeastlike cells convert into hyphae after a lag period corresponding to aerobic adaptation. Anaerobic cultures grown in the presence of ethylenediaminetetraacetate (EDTA) at a concentration of 10(-4) M exhibit hyphal morphology. These cells, which are fully adapted to anaerobic fermentation, nevertheless have potentially active mitochondria with the same levels of respiratory enzymes as ungerminated spores. These cells are able to grow immediately after aeration, without an adaptation lag. Evidence is presented which indicates that the morphogenetic effect of EDTA is not the result of elimination of free metals. Additional evidence proving mitochondrial control of morphogenesis in M. rouxii is that chloramphenicol (4 mg/ml) induced the formation of respiratory-deficient, yeastlike cells in aerobic cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353871"}
{"pmid": "4353874", "title": "Cross-feeding of Escherichia coli mutants defective in the biosynthesis of nicotinamide adenine dinucleotide.", "content": "Cross-feeding of Escherichia coli mutants defective in the biosynthesis of nicotinamide adenine dinucleotide. Mutants of Escherichia coli defective in the biosynthesis of nicotinamide adenine dinucleotide (NAD) are able to grow in a Casamino Acids medium lacking NAD and its immediate precursors, nicotinic acid and nicotinamide. This property has allowed the development of a system to measure cross-feeding between a nadA and a nadB mutant. This system provides a means of isolating the intermediate, prequinolinic acid, as well as a biological assay for the compound. The nadB mutant feeds the nadA mutant, indicating that the nadA enzyme occurs first in the pathway and the nadB enzyme second. No cross-feeding was detected between nadA and nadC or between nadB and nadC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353874"}
{"pmid": "4353873", "title": "Regulation of aspartokinase activity in Clostridium perfringens.", "content": "Regulation of aspartokinase activity in Clostridium perfringens. Cells of Clostridium perfringens type D apparently possess only a single species of aspartokinase. This enzyme has been partially purified and shown to be feedback inhibited by meso-diaminopimelate in an allosteric manner. The inhibitor exerts its action noncompetitively with respect to both substrates. The kinetic analysis further indicates that no homotropic cooperative interactions occur between either multiple substrate or inhibitor sites. Like aspartokinases from other bacteria, the clostridial enzyme is stimulated by the presence of either potassium or ammonium cations. A molecular weight of 102,000 was estimated for the enzyme following gel-filtration chromatography. Enzyme activity remains relatively constant throughout the growth cycle of the organism even well into the stationary growth phase. These results are discussed in terms of the role of the enzyme in the growth of the organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353873"}
{"pmid": "4353876", "title": "Factors in the identification of human skeletal remains.", "content": "Factors in the identification of human skeletal remains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353876"}
{"pmid": "4353875", "title": "The gua operon of Escherichia coli K-12: evidence for polarity from guaB to guaA.", "content": "The gua operon of Escherichia coli K-12: evidence for polarity from guaB to guaA. Guanine auxotrophs of Escherichia coli K-12 were isolated after mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine, ethyl methane sulfonate, or the acridine mustard ICR 372. guaA (xanthosine 5'-monophosphate [XMP] aminase-less) mutants were distinguished from guaB (inosine 5'-monophosphate [IMP] dehydrogenase-less) mutants by their growth response to xanthine and by enzyme assay. Mutations were classified as base substitutions or frameshift on the basis of mutagen-induced reversion patterns. All guaA strains, including three frameshift mutants, produced derepressed levels of IMP dehydrogenase when cultured with a growth-limiting concentration of guanine. The guaB strains were of two types: (i) those producing derepressed levels of XMP aminase, and (ii) those producing basal levels of XMP aminase when grown under conditions of guanine starvation. In the guaB strains of the second type, the expression of the adjacent guaA gene is reduced. It is proposed that this pleiotropic effect of some guaB mutations is a result of polarity. The orientation of polarity suggests the gene order \"operator\"-guaB-guaA. Gel diffusion studies with IMP dehydrogenase antiserum showed that strains carrying polar guaB mutations do not produce cross-reacting material (CRM). The remaining guaB mutants were either CRM(+) or CRM(-). Mapping the mutations by three-factor crosses showed that polar and nonpolar guaB sites are clustered in a small genetic region cotransducible with guaA. The relative positions of the guaB mutational sites established that the polar mutations lie within the structural gene for IMP dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353875"}
{"pmid": "4353878", "title": "The effect of synthetic peptide on chronic renal hypertension in the rat.", "content": "The effect of synthetic peptide on chronic renal hypertension in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353878"}
{"pmid": "4353877", "title": "Elevated circulating renin activity in rats following doses of cadmium known to induce hypertension.", "content": "Elevated circulating renin activity in rats following doses of cadmium known to induce hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353877"}
{"pmid": "4353879", "title": "Cord-blood low-density lipoprotein cholesterol: estimation versus measurement with the preparative ultracentrifuge.", "content": "Cord-blood low-density lipoprotein cholesterol: estimation versus measurement with the preparative ultracentrifuge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353879"}
{"pmid": "4353881", "title": "The nature of the granules within sulcular epithelial cells.", "content": "The nature of the granules within sulcular epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353881"}
{"pmid": "4353880", "title": "A dual precipitation method for quantitative plasma lipoprotein measurement without ultracentrifugation.", "content": "A dual precipitation method for quantitative plasma lipoprotein measurement without ultracentrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353880"}
{"pmid": "4353882", "title": "Hycanthone-induced hepatic changes in mice infected with Schistosoma mansoni.", "content": "Hycanthone-induced hepatic changes in mice infected with Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353882"}
{"pmid": "4353884", "title": "Comparative study of the action of phenothiazine and para-fluorobutyrophenone derivatives on rat brain membranes using the spin label technique.", "content": "Comparative study of the action of phenothiazine and para-fluorobutyrophenone derivatives on rat brain membranes using the spin label technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353884"}
{"pmid": "4353883", "title": "Adrenergic-adenosine 3',5'-monophosphate regulation of serotonin N-acetyltransferase activity and the temporal relationship of serotonin N-acetyltransferase activity synthesis of 3H-N-acetylserotonin and 3H-melatonin in the cultured rat pineal gland.", "content": "Adrenergic-adenosine 3',5'-monophosphate regulation of serotonin N-acetyltransferase activity and the temporal relationship of serotonin N-acetyltransferase activity synthesis of 3H-N-acetylserotonin and 3H-melatonin in the cultured rat pineal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353883"}
{"pmid": "4353885", "title": "Renin-angiotensin system in human hypertension due to segmental renal ischemia.", "content": "Renin-angiotensin system in human hypertension due to segmental renal ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353885"}
{"pmid": "4353886", "title": "Enhancement of the inotropic action of glucagon by small concentration of angiotensin.", "content": "Enhancement of the inotropic action of glucagon by small concentration of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353886"}
{"pmid": "4353888", "title": "Bursa-dependent and thymus-dependent \"surveillance\" of a virus-induced tumour in the chicken.", "content": "Bursa-dependent and thymus-dependent \"surveillance\" of a virus-induced tumour in the chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353888"}
{"pmid": "4353887", "title": "Ultrastructure of a human chorionic gonadotropin-and adrenocorticotropin-responsive functioning Sertoli-Leydig cell tumor (type I).", "content": "Ultrastructure of a human chorionic gonadotropin-and adrenocorticotropin-responsive functioning Sertoli-Leydig cell tumor (type I).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353887"}
{"pmid": "4353889", "title": "Fucosylglycolipid metabolism in oncornavirus-transformed cell lines.", "content": "Fucosylglycolipid metabolism in oncornavirus-transformed cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353889"}
{"pmid": "4353890", "title": "Oestrogenic stimulation of macromolecular synthesis is correlated with nuclear hormone-receptor complex in neonatal rat uterus.", "content": "Oestrogenic stimulation of macromolecular synthesis is correlated with nuclear hormone-receptor complex in neonatal rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353890"}
{"pmid": "4353891", "title": "Variations among sublines of inbred AKR mice.", "content": "Variations among sublines of inbred AKR mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353891"}
{"pmid": "4353893", "title": "Secretion of growth hormone in the rat.", "content": "Secretion of growth hormone in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353893"}
{"pmid": "4353892", "title": "The intestinal flora of pigs with special reference to Clostridium perfringens.", "content": "The intestinal flora of pigs with special reference to Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353892"}
{"pmid": "4353894", "title": "Prostaglandin receptors in the hamster uterus during the estrous cycle.", "content": "Prostaglandin receptors in the hamster uterus during the estrous cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353894"}
{"pmid": "4353896", "title": "Correlation between measures of the rapid eye movements of wakefulness and sleep.", "content": "Correlation between measures of the rapid eye movements of wakefulness and sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353896"}
{"pmid": "4353897", "title": "REM sleep interruption: experimental shortening of REM period duration.", "content": "REM sleep interruption: experimental shortening of REM period duration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353897"}
{"pmid": "4353900", "title": "Brain tumor types induced by the Schmidt-Ruppin strain of Rous sarcoma virus in inbred Fischer rats.", "content": "Brain tumor types induced by the Schmidt-Ruppin strain of Rous sarcoma virus in inbred Fischer rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353900"}
{"pmid": "4353899", "title": "Light and electron microscopic studies of mouse CNS after subcutaneous administration of the E and M variants of the encephalomyocarditis virus.", "content": "Light and electron microscopic studies of mouse CNS after subcutaneous administration of the E and M variants of the encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353899"}
{"pmid": "4353903", "title": "The effects of methoxyflurane on sympathetic ganglionic transmission.", "content": "The effects of methoxyflurane on sympathetic ganglionic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353903"}
{"pmid": "4353902", "title": "Tear flow in man.", "content": "Tear flow in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353902"}
{"pmid": "4353911", "title": "Phase transitions in lipids.", "content": "Phase transitions in lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353911"}
{"pmid": "4353912", "title": "Motion of spin labeled fatty acids in membrane structures.", "content": "Motion of spin labeled fatty acids in membrane structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353912"}
{"pmid": "4353905", "title": "Interrelationship between the kinds of dietary carbohydrate and fat in hyperlipoproteinemic patients. 1. Sucrose and starch with polyunsaturated fat.", "content": "Interrelationship between the kinds of dietary carbohydrate and fat in hyperlipoproteinemic patients. 1. Sucrose and starch with polyunsaturated fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353905"}
{"pmid": "4353913", "title": "Membrane lipid pattern and non-electrolytes permeability in Salmo trutta L. red blood cells.", "content": "Membrane lipid pattern and non-electrolytes permeability in Salmo trutta L. red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353913"}
{"pmid": "4353915", "title": "Inhibitory effect of chick interferon and interferon inducer (rI:rC) on the induction of cellular DNA synthesis and transformation of chick embryo fibroblasts infected in culture with Rous sarcoma virus.", "content": "Inhibitory effect of chick interferon and interferon inducer (rI:rC) on the induction of cellular DNA synthesis and transformation of chick embryo fibroblasts infected in culture with Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353915"}
{"pmid": "4353918", "title": "Sperm velocity and morphology in 1727 ejaculates with normal sperm count.", "content": "Sperm velocity and morphology in 1727 ejaculates with normal sperm count.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353918"}
{"pmid": "4353917", "title": "The prevention of postoperative pelvic adhesions following conservative operative treatment for human infertility. A final 3-year follow-up report.", "content": "The prevention of postoperative pelvic adhesions following conservative operative treatment for human infertility. A final 3-year follow-up report. A combination of Decadreon (dexamethasone) and Phenergan (promethazine) was tested in this collaborative study of 240 infertility patients as a means of preventing postoperative adhesion formation after simple pelvic surgery.  24 patients were lost to follow-up.  The overall pregnancy rate among the 240 patients was 51.7% (124): 49% with primary infertility and 58% with secondary infertility conceived after surgery.  90 full-term deliveries were recorded, 27 spontaneous abortions occurred, and 7 ectopic gestations were conceived.  In all, 31 cases were reinspected for various reasons after the drug treatment postsurgery;  42% showed no adhesions, 23% showed minimal adhesions, and 35% had significant adhesions.  Complications coincident with use of the combined medication were seen in 2.2% (11 of 240) patients.  Though this study lacked controls, the authors feel thta the use of corticosteroids postoperatively after pelvic intervention may control the numbers of adhesions which form postoperatively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353917"}
{"pmid": "4353908", "title": "Effect of dietary starches on the serum, aorta and hepatic lipid levels in cholesterol-fed rats.", "content": "Effect of dietary starches on the serum, aorta and hepatic lipid levels in cholesterol-fed rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353908"}
{"pmid": "4353919", "title": "Plasma LH-HCG, 17 -estradiol, estrone and progesterone monitoring around ovulation and subsequent nidation.", "content": "Plasma LH-HCG, 17 -estradiol, estrone and progesterone monitoring around ovulation and subsequent nidation. At the University Hospital in Louvain, Belgium, plasma hormonal fluctuations in 6 women, aged 16-46, were studied.  Measurements were made during the nonpregnant state and in the 4 women who conceived also in the period around nidation.  Measurements during the nonpregnant state yielded expected results: Preovulatory midcycle luteinizing hormone (LH) surge preceded by increase of estrone and estradiol, sudden fall of estrogens and rise of progesterone during or just after LH  surge, and secondary estrogen rise together with progesterone peak during the luteal phase accurred.  In the women implantation occurred, human chorionic gonadotropin (HCG) started to rise sharply 10 or 11 days after the LH surge.  Progesterone and estrogen levels remained high during the implantation period.  In the patient who aborted at 17 weeks of pregnancy, the HCG rise was slower and the secondary rise of estradiol was rather limited; progesterone levels, however, appeared to be normal.  An estradiol surge may occur just prior to implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353919"}
{"pmid": "4353907", "title": "Interrelationship between the kinds of dietary carbohydrate and fat in hyperlipoproteinemic patients. 3. Synergistic effect of sucrose and animal fat on serum lipids.", "content": "Interrelationship between the kinds of dietary carbohydrate and fat in hyperlipoproteinemic patients. 3. Synergistic effect of sucrose and animal fat on serum lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353907"}
{"pmid": "4353920", "title": "Penetration of spermatozoa into the uterine mucosa: a possible cause of infertility in the human.", "content": "Penetration of spermatozoa into the uterine mucosa: a possible cause of infertility in the human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353920"}
{"pmid": "4353921", "title": "Clomifen in the treatment of anovulatory women.", "content": "Clomifen in the treatment of anovulatory women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353921"}
{"pmid": "4353906", "title": "Interrelationship between the kinds of dietary carbohydrate and fat in hyperlipoproteinemic patients. 2. Sucrose and starch with mixed saturated and polyunsaturated fats.", "content": "Interrelationship between the kinds of dietary carbohydrate and fat in hyperlipoproteinemic patients. 2. Sucrose and starch with mixed saturated and polyunsaturated fats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353906"}
{"pmid": "4353923", "title": "The effect of synthetic luteinizing hormone-releasing hormone on blood levels of luteinizing hormone and follicle stimulating hormone in Klinefelter patients.", "content": "The effect of synthetic luteinizing hormone-releasing hormone on blood levels of luteinizing hormone and follicle stimulating hormone in Klinefelter patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353923"}
{"pmid": "4353922", "title": "Sonographic visualization of coexisting gestation sac and I.U.D. in the uterus and a consideration of a causative factor of accidental pregnancy.", "content": "Sonographic visualization of coexisting gestation sac and I.U.D. in the uterus and a consideration of a causative factor of accidental pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353922"}
{"pmid": "4353924", "title": "Reactions between nitroxyls and radiation-induced long-lived DNA-transients.", "content": "Reactions between nitroxyls and radiation-induced long-lived DNA-transients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353924"}
{"pmid": "4353910", "title": "Effect of a hypolipidaemic drug (CH 13,437) on plasma and tissue lipids, and on the intravenous fat tolerance in man.", "content": "Effect of a hypolipidaemic drug (CH 13,437) on plasma and tissue lipids, and on the intravenous fat tolerance in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353910"}
{"pmid": "4353925", "title": "H-adduct radicals in x-irradiated frozen solutions of uracil derivatives.", "content": "H-adduct radicals in x-irradiated frozen solutions of uracil derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353925"}
{"pmid": "4353909", "title": "Plasma phospholipids in type IV hyperlipoproteinemia.", "content": "Plasma phospholipids in type IV hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353909"}
{"pmid": "4353926", "title": "Radical yield in x-irradiated biological molecules. I. Glycine.", "content": "Radical yield in x-irradiated biological molecules. I. Glycine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353926"}
{"pmid": "4353928", "title": "The pathogenesis of corneal inflammation due to Herpes simplex virus. I. Corneal hypersensitivity in the rabbit.", "content": "The pathogenesis of corneal inflammation due to Herpes simplex virus. I. Corneal hypersensitivity in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353928"}
{"pmid": "4353927", "title": "Role of cyclic AMP in mitogen induced transformation of human peripheral leukocytes.", "content": "Role of cyclic AMP in mitogen induced transformation of human peripheral leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353927"}
{"pmid": "4353929", "title": "Neutralizing antibodies to Epstein-Barr virus in healthy populations and patients with infectious mononucleosis.", "content": "Neutralizing antibodies to Epstein-Barr virus in healthy populations and patients with infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353929"}
{"pmid": "4353930", "title": "Herpesvirus hominis infection in newborn mice. I. An experimental model and therapy with iododeoxyuridine.", "content": "Herpesvirus hominis infection in newborn mice. I. An experimental model and therapy with iododeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353930"}
{"pmid": "4353931", "title": "Experimental animal model for encephalitis due to herpes simplex virus.", "content": "Experimental animal model for encephalitis due to herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353931"}
{"pmid": "4353932", "title": "Isolation of herpesviruses from trigeminal ganglia of man, monkeys, and cats.", "content": "Isolation of herpesviruses from trigeminal ganglia of man, monkeys, and cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353932"}
{"pmid": "4353933", "title": "Viruses causing common respiratory infections in man. II. Enteroviruses and paramyxoviruses.", "content": "Viruses causing common respiratory infections in man. II. Enteroviruses and paramyxoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353933"}
{"pmid": "4353934", "title": "The role of water in the origin of life and its function in the primitive gene.", "content": "The role of water in the origin of life and its function in the primitive gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353934"}
{"pmid": "4353935", "title": "Relation between the reaction cytochrome oxidase-oxygen and oxygen uptake in cells in vivo. The role of diffusion.", "content": "Relation between the reaction cytochrome oxidase-oxygen and oxygen uptake in cells in vivo. The role of diffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353935"}
{"pmid": "4353942", "title": "Virus specific surface antigen in cells productively infected with polyoma virus.", "content": "Virus specific surface antigen in cells productively infected with polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353942"}
{"pmid": "4353941", "title": "Infection with herpes-simplex viruses 1 and 2. 3.", "content": "Infection with herpes-simplex viruses 1 and 2. 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353941"}
{"pmid": "4353943", "title": "Intracranial tumors of apoplectiform onset.", "content": "Intracranial tumors of apoplectiform onset.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353943"}
{"pmid": "4353944", "title": "Resistance of rabbit corneal epithelium to herpes simplex virus.", "content": "Resistance of rabbit corneal epithelium to herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353944"}
{"pmid": "4353946", "title": "Bacterial infections in immunosuppressed patients: diagnosis and management.", "content": "Bacterial infections in immunosuppressed patients: diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353946"}
{"pmid": "4353947", "title": "Immunosuppression and virus infections.", "content": "Immunosuppression and virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353947"}
{"pmid": "4353948", "title": "Histocompatibility antigens of human plasma. Localization to the HLD-3 lipoprotein fraction.", "content": "Histocompatibility antigens of human plasma. Localization to the HLD-3 lipoprotein fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353948"}
{"pmid": "4353949", "title": "Transduction by bacteriophage MU-1.", "content": "Transduction by bacteriophage MU-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353949"}
{"pmid": "4353950", "title": "Polyoma gene function required for viral DNA synthesis.", "content": "Polyoma gene function required for viral DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353950"}
{"pmid": "4353951", "title": "Testing by the \"paired-label\" antibody binding technique for feline leukemia virus-induced cell surface antigens (FeLV-CSA) on the surface of human rhabdomyosarcoma cells releasing RD-114 virus.", "content": "Testing by the \"paired-label\" antibody binding technique for feline leukemia virus-induced cell surface antigens (FeLV-CSA) on the surface of human rhabdomyosarcoma cells releasing RD-114 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353951"}
{"pmid": "4353952", "title": "Murine mammary tumor cell clones with varying degrees of virus expression.", "content": "Murine mammary tumor cell clones with varying degrees of virus expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353952"}
{"pmid": "4353953", "title": "Effect of 2-deoxy-D-glucose on cell fusion induced by Newcastle disease and herpes simplex viruses.", "content": "Effect of 2-deoxy-D-glucose on cell fusion induced by Newcastle disease and herpes simplex viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353953"}
{"pmid": "4353954", "title": "Structural components of Sendai virus. Serological and physicochemical characterization of hemagglutinin subunit associated with neuraminidase activity.", "content": "Structural components of Sendai virus. Serological and physicochemical characterization of hemagglutinin subunit associated with neuraminidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353954"}
{"pmid": "4353955", "title": "Studies on herpes simplex virus DNA: denaturation properties.", "content": "Studies on herpes simplex virus DNA: denaturation properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353955"}
{"pmid": "4353956", "title": "Malignant transformation of hamster embryo fibroblasts following exposure to ultraviolet-irradiated human cytomegalovirus.", "content": "Malignant transformation of hamster embryo fibroblasts following exposure to ultraviolet-irradiated human cytomegalovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353956"}
{"pmid": "4353957", "title": "Synthesis of Epstein-Barr virus antigens and DNA in activated Burkitt somatic cell hybrids.", "content": "Synthesis of Epstein-Barr virus antigens and DNA in activated Burkitt somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353957"}
{"pmid": "4353958", "title": "Fine structural alterations with age in the fat body of the adult male housefly, Musca domestica.", "content": "Fine structural alterations with age in the fat body of the adult male housefly, Musca domestica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353958"}
{"pmid": "4353959", "title": "Quantitative microscopical studies of the mouse peritoneal macrophage following stimulation in vivo.", "content": "Quantitative microscopical studies of the mouse peritoneal macrophage following stimulation in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353959"}
{"pmid": "4353960", "title": "The development of synapses in vitro between previously dissociated chick spinal cord neurons.", "content": "The development of synapses in vitro between previously dissociated chick spinal cord neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353960"}
{"pmid": "4353962", "title": "Ultrastructural localization of glycogen in erythrocytes and developing erythrocytic cells in normal human bone marrow.", "content": "Ultrastructural localization of glycogen in erythrocytes and developing erythrocytic cells in normal human bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353962"}
{"pmid": "4353963", "title": "Fine structure of the adenohypophysis in immature sockeye salmon, Oncorhynchus nerka.", "content": "Fine structure of the adenohypophysis in immature sockeye salmon, Oncorhynchus nerka.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353963"}
{"pmid": "4353964", "title": "Ultrastructure of the pseudohermaphrodite rat testis.", "content": "Ultrastructure of the pseudohermaphrodite rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353964"}
{"pmid": "4353966", "title": "Observations on skin structure and sloughing in the stone fish Synanceja verrucosa and related fish species as a functional adaptation to their mode of life.", "content": "Observations on skin structure and sloughing in the stone fish Synanceja verrucosa and related fish species as a functional adaptation to their mode of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353966"}
{"pmid": "4353965", "title": "An analysis of some aspects of synaptosomal ultrastructure by the use of serial sections.", "content": "An analysis of some aspects of synaptosomal ultrastructure by the use of serial sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353965"}
{"pmid": "4353969", "title": "Small-sized haemagglutinin of vesicular stomatitis virus released spontaneously and with Nonidet P 40.", "content": "Small-sized haemagglutinin of vesicular stomatitis virus released spontaneously and with Nonidet P 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353969"}
{"pmid": "4353970", "title": "Typing of Herpesvirus hominis strains by indirect immunofluorescence and biological markers.", "content": "Typing of Herpesvirus hominis strains by indirect immunofluorescence and biological markers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353970"}
{"pmid": "4353972", "title": "Granular cell myoblastoma of multicentric origin involving the vulva: a case report.", "content": "Granular cell myoblastoma of multicentric origin involving the vulva: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353972"}
{"pmid": "4353971", "title": "Spin changes in hemoproteins.", "content": "Spin changes in hemoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353971"}
{"pmid": "4353973", "title": "The Chediak-Higashi syndrome. Fine structure of giant inclusions in freeze-fractured neutrophils.", "content": "The Chediak-Higashi syndrome. Fine structure of giant inclusions in freeze-fractured neutrophils. The technic of freeze-fracture and etching has been used in the present study to examine the fine structure of giant inclusions in circulating leukocytes from a patient with the Chediak-Higashi syndrome (CHS). The surface granularity of the membranes enclosing the giant inclusions differed slightly from that of normal sized organelles. Two types of giant granules were distinguished in replicas of freeze-fractured CHS neutrophils. The difference in fine structure suggests that one variety is a massively enlarged, but essentially unaltered primary lysosome, while the other develops as a result of continued fusion of small organelles with huge inclusions throughout the stages of polymorphonuclear leukocyte maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353973"}
{"pmid": "4353974", "title": "Evolving behavior in the clinical and experimental amphetamine (model) psychosis.", "content": "Evolving behavior in the clinical and experimental amphetamine (model) psychosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353974"}
{"pmid": "4353975", "title": "The dream-protein hypothesis.", "content": "The dream-protein hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353975"}
{"pmid": "4353976", "title": "Alterations of liver metabolism associated with experimental acute pancreatitis.", "content": "Alterations of liver metabolism associated with experimental acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353976"}
{"pmid": "4353977", "title": "Diarrheogenic tumor of the pancreas.", "content": "Diarrheogenic tumor of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353977"}
{"pmid": "4353979", "title": "Nonbacterial pneumonitis with antineoplastic therapy.", "content": "Nonbacterial pneumonitis with antineoplastic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353979"}
{"pmid": "4353981", "title": "Enuresis.", "content": "Enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353981"}
{"pmid": "4353982", "title": "Active, water-insoluble derivatives of D-glucose oxidase and alginic acid, chitin, and Celite.", "content": "Active, water-insoluble derivatives of D-glucose oxidase and alginic acid, chitin, and Celite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353982"}
{"pmid": "4353980", "title": "Etiology of breast cancer. II. Epidemiologic aspects.", "content": "Etiology of breast cancer. II. Epidemiologic aspects. The epidemiology of breast cancer is reviewed with particular emphasis on its etiology. A number of studies suggest that differences in breast cancer incidence are associated with differences in marital status, number of pregnancies, age at menarche, age at menopause, height and weight, socioeconomic status, geographic location and residence. However, in no case is the evidence adequate to establish a \"cause and effect\" relationship. The genetic component of these associations may be of primary importance, while other conditions such as marital status are probably indirect reflections of the operation of more fundamental factors.There is a general consensus that endocrine factors play an important part in mammary cancer occurrence. At present, the association between breast cancer and the presence of the virus-like (type B) particles in human milk is not established.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353980"}
{"pmid": "4353984", "title": "Measurement of urinary aldosterone by a simplified radioimmunoassay procedure.", "content": "Measurement of urinary aldosterone by a simplified radioimmunoassay procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353984"}
{"pmid": "4353983", "title": "Automated primary screening for hyperlipoproteinemias.", "content": "Automated primary screening for hyperlipoproteinemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353983"}
{"pmid": "4353986", "title": "Action of imipramine on a serotonergic synapse.", "content": "Action of imipramine on a serotonergic synapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353986"}
{"pmid": "4353985", "title": "The effects of hemicholinium-3 in an insect neuromuscular preparation.", "content": "The effects of hemicholinium-3 in an insect neuromuscular preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353985"}
{"pmid": "4353987", "title": "Acetylcholine receptors and the diphasic action of nicotine in the American cockroach, Periplaneta americana (L.).", "content": "Acetylcholine receptors and the diphasic action of nicotine in the American cockroach, Periplaneta americana (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353987"}
{"pmid": "4353988", "title": "Glycogenolysis and lipolysis in Gallus domesticus during the perinatal period.", "content": "Glycogenolysis and lipolysis in Gallus domesticus during the perinatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353988"}
{"pmid": "4353989", "title": "Pituitary-adrenal axis activation as a function of hypothalamic 5-hydroxytryptamine titre.", "content": "Pituitary-adrenal axis activation as a function of hypothalamic 5-hydroxytryptamine titre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353989"}
{"pmid": "4353990", "title": "Neuromuscular block in insects caused by the venom of the digger wasp Philanthus triangulum F.", "content": "Neuromuscular block in insects caused by the venom of the digger wasp Philanthus triangulum F.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353990"}
{"pmid": "4353991", "title": "Transmitter substances in insects: a review.", "content": "Transmitter substances in insects: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353991"}
{"pmid": "4353993", "title": "High resolution deuterium magnetic resonance: an approach to the study of molecular organization in biological membranes and model systems.", "content": "High resolution deuterium magnetic resonance: an approach to the study of molecular organization in biological membranes and model systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353993"}
{"pmid": "4353992", "title": "Anaerobic cilio-excitation and metabolic stimulation by 5-hydroxytryptamine in bivalve gill.", "content": "Anaerobic cilio-excitation and metabolic stimulation by 5-hydroxytryptamine in bivalve gill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353992"}
{"pmid": "4353994", "title": "Activation by glucose of adenyl cyclase in pancreatic islets of the rat.", "content": "Activation by glucose of adenyl cyclase in pancreatic islets of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353994"}
{"pmid": "4353995", "title": "Intracranial tumors in India: incidence and variations.", "content": "Intracranial tumors in India: incidence and variations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353995"}
{"pmid": "4353996", "title": "Incidence and behavior pattern of intracranial tumors in Ceylon.", "content": "Incidence and behavior pattern of intracranial tumors in Ceylon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353996"}
{"pmid": "4353997", "title": "Nerve sheath tumors.", "content": "Nerve sheath tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353997"}
{"pmid": "4353998", "title": "Demonstration of iodide transport defect but normal iodide organification in nonfunctioning nodules of human thyroid glands.", "content": "Demonstration of iodide transport defect but normal iodide organification in nonfunctioning nodules of human thyroid glands. Benign and malignant nodules in human thyroid glands, which did not concentrate iodide in vivo, were also unable to accumulate iodide in vitro. The mean thyroid-to-medium ratio (T/M) in seven benign nodules was 0.8+/-0.2 compared with 7+/-2 in adjacent normal thyroid tissue. In four malignant thyroid nodules, the mean T/M was 0.5+/-0.1 compared with 11+/-4 in adjacent normal thyroid. Despite the inability of such nodules to concentrate iodide, iodide organification was present but was only one-half to one-third as active as in surrounding normal thyroid. Thyroid-stimulating hormone (TSH) increased iodide organification equally in both benign nodules and normal thyroid although it had no effect in three of the four malignant lesions. The reduction in organification is probably related to the absence of iodide transport, since incubation of normal thyroid slices with perchlorate caused similar diminution in iodide incorporation but no change in the response to TSH. Monoiodotyrosine (MIT) and di-iodotyrosine (DIT) accounted for most of the organic iodide in both the nodules and normal tissue. The MIT/DIT ratio was similar in normal and nodule tissue. The normal tissue contained much more inorganic iodide than the nodules, consistent with the absence of the iodide trap in the latter tissue. The thyroxine content of normal thyroid was 149+/-17 mug/g wet wt and 18+/-4 mug/g wet wt in the nodules. The transport defect in the nodules was not associated with any reduction in total, Na(+)-K(+)- or Mg(++)-activated ATPase activities or the concentration of ATP. Basal adenylate cyclase was higher in nodules than normal tissue. Although there was no difference between benign and malignant nodules, the response of adenylate cyclase to TSH was greater in the benign lesions. These studies demonstrate that nonfunctioning thyroid nodules, both benign and malignant, have a specific defect in iodide transport that accounts for their failure to accumulate radioactive iodide in vivo. In benign nodules, iodide organification was increased by TSH while no such effect was found in three of four malignant lesions, suggesting additional biochemical defects in thyroid carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353998"}
{"pmid": "4354001", "title": "AY-9944 inhibition of sterol biosynthesis in Chlorella emersonii.", "content": "AY-9944 inhibition of sterol biosynthesis in Chlorella emersonii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354001"}
{"pmid": "4354002", "title": "Search for prostaglandin A1 in onion.", "content": "Search for prostaglandin A1 in onion. Thus far there have been no reports that prostaglandins have been isolated from plant materials.  Numerous plant materials were screened using this layer chromatographic technique to determine if such materials could contain prostaglandins.  Following this initial screening, onions were selected for further study.  A fatty acid fraction separated from yellow onion was subjected to thin layer chromatographic techniques, UV and IR spectrophotometric analyses.  This silicic acid-chromatographed fraction corresponded to the prostaglandin A1 fraction.  Preliminary identification strongly suggested that this component of onions appeared to be a prostaglandin (PGA1) or a prostaglandin-like compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354002"}
{"pmid": "4354000", "title": "Collagen-mediated platelet aggregation. Effects of collagen modification involving the protein and carbohydrate moieties.", "content": "Collagen-mediated platelet aggregation. Effects of collagen modification involving the protein and carbohydrate moieties. In an effort to elucidate the nature of the collagen-platelet interaction, the effects of collagen modification on platelet aggregation have been studied. We have shown that purified rat skin (salt) soluble collagen is effective at about 20 nM in mediating platelet aggregation in human platelet-rich plasma. This concentration is somewhat greater than that required of several skin insoluble collagens (ca. 10 nM). Both the alpha1(I) and alpha2 chains from rat skin soluble collagen produced platelet aggregation, but only at concentrations of about 13 muM and 55 muM, respectively. In contrast, heat-denatured collagen and chains (e.g., 65 muM alpha1(I) and 160 muM alpha2) failed to induce platelet aggregation and to inhibit platelet aggregation by native collagen. Glycopeptides were prepared from human skin insoluble collagen by extended digestion with bacterial collagenase and trypsin, and were purified by gel filtration into two classes. One class of higher molecular weight contained sialic acid, glucosamine, galactosamine, fucose, mannose, galactose, and glucose, and the other of lower molecular weight consisted primarily of a mixture of galactose and galactosyl-glucose units O-glycosidically linked to hydroxylysine-containing peptides. We found that, after the residual tryptic activity contaminating the higher molecular weight fraction was inhibited, neither of the glycopeptide classes produced nor inhibited native human skin insoluble collagen-mediated platelet aggregation at the highest concentration examined (ca. 1-2 mg glycopeptide per ml of platelet-rich plasma). Highly purified samples of the hydroxylysyl glycosides, hydroxylysylgalactose and hydroxylysylgalactosylglucose (Hyl-Gal and Hyl-Gal-Glc, respectively), were prepared from human urine and labeled at galactose using galactose oxidase followed by reduction with tritiated borohydride. Binding studies with platelet-rich plasma showed that, at concentrations greater than 50 nM, Hyl-Gal gives apparent binding to platelets, but there was no evidence of Hyl-Gal-Glc binding to platelets at concentrations up to 250 nM. At concentrations several hundredfold higher than the equivalents present in the minimum concentration of rat skin soluble collagen required for platelet aggregation, neither Hyl-Gal (at 29 muM) nor Hyl-Gal-Glc (at 18 muM) caused platelet aggregation or inhibited platelet aggregation by native collagen. Also, at a concentration of 85 muM (which represents a concentration about two thousandfold higher than the equivalents in the minimum concentration of soluble collagen required for platelet aggregation) the Gal-Glc-containing 36 residue rat skin soluble collagen alpha1(I)cyanogen bromide #5 peptide had no platelet aggregating or inhibiting activity. Modification of at least 90% of the rat skin soluble collagen carbohydrate by mild periodate oxidation had no effect on the platelet aggregating activity. Human skin insoluble collagen was reacted with periodate under the same conditions, and this had no demonstrable effect on its ability to induce platelet aggregation. This indicates that the normal carbohydrate side chains of these collagens are not required for the platelet interaction that produces the release of ADP and other metabolic constituents and leads to aggregation.Thus, collagen-platelet interactions appear to involve at least two distinct binding sites on the platelet plasma membrane. One is a protein binding site that activates platelet aggregation and has high specificity and affinity for the collagen triple-helical fold or perhaps even for a particular amino acid sequence in the triple helix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354000"}
{"pmid": "4353999", "title": "The kinetics of intramolecular distribution of 15N in uric acid after administration of (15N) glycine. A reappraisal of the significance of preferential labeling of N-(3+9) of uric acid in primary gout.", "content": "The kinetics of intramolecular distribution of 15N in uric acid after administration of (15N) glycine. A reappraisal of the significance of preferential labeling of N-(3+9) of uric acid in primary gout. THE CONCEPT OF AN ABNORMALITY OF GLUTAMINE METABOLISM IN PRIMARY GOUT WAS FIRST PROPOSED ON THE BASIS OF ISOTOPE DATA: when [(15)N]glycine was administered to gouty subjects, there was disproportionately great enrichment of N-(3 + 9) of uric acid, which derive from the amide-N of glutamine. An unduly high concentration of (15)N in glutamine was postulated, and attributed to a hypothetical defect in catabolism of glutamine. Excess glutamine was proposed as the driving force of uric acid overproduction. WE HAVE REEXAMINED THIS PROPOSITION IN FOUR GOUTY SUBJECTS: one mild overproducer of uric acid with \"idiopathic gout,\" one marked overproducer with high-grade but \"partial\" hypoxanthine-guanine phosphoribosyl-transferase deficiency, and two extraordinary overproducers with superactive phosphoribosylpyrophosphate synthetases. In the last three, the driving force of excessive purine biosynthesis is a known surplus of alpha-5-phosphoribosyl-1-pyrophosphate. Disproportionately high labeling of N-(3 + 9) was present in all four gouty subjects, most marked in the most flamboyant overproducers. The precursor glucine pool was sampled by periodic administration of benzoic acid and isolation of urinary hippuric acid. Similarly, the precursor glutamine pool was sampled by periodic administration of phenylacetic acid and isolation of the amide-N of urinary phenylacetylglutamine. The time course of (15)N enrichment of hippurate differed from that of the amide-N of glutamine. Whereas initial enrichment values of hippurate were very high, those of glutamine-amide-N were low, increasing to a maximum at about 3 h, and then declining less rapidly than those of hippurate. However, enrichment values of hippurate and of phenacetyl glutamine were normal in all of the gouty subjects studied. Thus, preferential enrichment of N-(3 + 9) in gouty overproducers given [(15)N]glycine does not necessarily reflect a specific abnormality of glutamine metabolism, but rather appears to be a kinetic phenomenon associated with accelerated purine biosynthesis per se.In addition, greater enrichment of N-9 than of N-3 on days 1 and 2 provided suggestive evidence for a second pathway for synthesis of the initial precursor of purine biosynthesis, phosphoribosylamine, perhaps utilizing ammonia rather than the amide-N of glutamine as nitrogen donor. In this limited study, the activity of this potential second pathway did not appear to be selectively increased in gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4353999"}
{"pmid": "4354003", "title": "The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.", "content": "The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354003"}
{"pmid": "4354004", "title": "Analogues of adenosine 3',-5'-cyclic phosphate as activators of phosphorylase b kinase and as substrates for cyclic 3',5'-nucleotide phosphodiesterase.", "content": "Analogues of adenosine 3',-5'-cyclic phosphate as activators of phosphorylase b kinase and as substrates for cyclic 3',5'-nucleotide phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354004"}
{"pmid": "4354005", "title": "A kinetic model of a cyclic system for the fluorometric microdetermination of adenosine triphosphatase activity.", "content": "A kinetic model of a cyclic system for the fluorometric microdetermination of adenosine triphosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354005"}
{"pmid": "4354006", "title": "Study of the mechanism of renal vacuologenesis induced in the rat by ethylenediaminetetraacetate. Comparison of the cellular activities of calcium and chromium chelates.", "content": "Study of the mechanism of renal vacuologenesis induced in the rat by ethylenediaminetetraacetate. Comparison of the cellular activities of calcium and chromium chelates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354006"}
{"pmid": "4354007", "title": "Adverse effect of cytosine arabinoside on disseminated zoster in a controlled trial.", "content": "Adverse effect of cytosine arabinoside on disseminated zoster in a controlled trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354007"}
{"pmid": "4354008", "title": "Stimulation of yeast RNA synthesis by cycloheximide and 3',5'-cyclic AMP.", "content": "Stimulation of yeast RNA synthesis by cycloheximide and 3',5'-cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354008"}
{"pmid": "4354009", "title": "ATP requirement for release of adenovirus mRNA from isolated nuclei.", "content": "ATP requirement for release of adenovirus mRNA from isolated nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354009"}
{"pmid": "4354010", "title": "Alkaline phosphatase in vascular smooth muscle.", "content": "Alkaline phosphatase in vascular smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354010"}
{"pmid": "4354011", "title": "Angiotensin receptors in smooth muscle cell membranes.", "content": "Angiotensin receptors in smooth muscle cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354011"}
{"pmid": "4354012", "title": "Plasma membrane proteins of normal and Rous sarcoma virus-transformed chick-embryo fibroblasts.", "content": "Plasma membrane proteins of normal and Rous sarcoma virus-transformed chick-embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354012"}
{"pmid": "4354013", "title": "Stimulation of calcitonin release in vitro by purine and pyrimidine nucleotides.", "content": "Stimulation of calcitonin release in vitro by purine and pyrimidine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354013"}
{"pmid": "4354015", "title": "Modification of expression of the testicular feminization (Tfm) gene of the mouse by a \"controlling element\" gene.", "content": "Modification of expression of the testicular feminization (Tfm) gene of the mouse by a \"controlling element\" gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354015"}
{"pmid": "4354014", "title": "Antisynaptosome antibodies affect synaptosomal permeability to neurotransmitters.", "content": "Antisynaptosome antibodies affect synaptosomal permeability to neurotransmitters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354014"}
{"pmid": "4354017", "title": "REM sleep deprivation impairs latent extinction in rats.", "content": "REM sleep deprivation impairs latent extinction in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354017"}
{"pmid": "4354016", "title": "Long-term results of breast cancer treatment during 1959-1966.", "content": "Long-term results of breast cancer treatment during 1959-1966.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354016"}
{"pmid": "4354019", "title": "Serum levels of parathyroid hormone in the Zollinger-Ellison syndrome.", "content": "Serum levels of parathyroid hormone in the Zollinger-Ellison syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354019"}
{"pmid": "4354018", "title": "The brain scan.", "content": "The brain scan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354018"}
{"pmid": "4354020", "title": "On the development of insulin sensitivity by mouse mammary gland in vitro.", "content": "On the development of insulin sensitivity by mouse mammary gland in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354020"}
{"pmid": "4354021", "title": "Effects of adenosine-3',5'-monophosphate and 5-hydroxytryptamine on the secretory activity of the canine testis.", "content": "Effects of adenosine-3',5'-monophosphate and 5-hydroxytryptamine on the secretory activity of the canine testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354021"}
{"pmid": "4354024", "title": "Quantitative differential thermal analysis of small dust samples containing quartz.", "content": "Quantitative differential thermal analysis of small dust samples containing quartz.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354024"}
{"pmid": "4354025", "title": "Bureau of Mines procedure for analysis of respirable dust from coal mines.", "content": "Bureau of Mines procedure for analysis of respirable dust from coal mines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354025"}
{"pmid": "4354026", "title": "A monumental study--reconstruction of a 1920 granite shed.", "content": "A monumental study--reconstruction of a 1920 granite shed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354026"}
{"pmid": "4354028", "title": "Isolation of polypeptides containing the intermolecular cross-link  , '-dihydroxylysinonorleucine from dentin collagen.", "content": "Isolation of polypeptides containing the intermolecular cross-link  , '-dihydroxylysinonorleucine from dentin collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354028"}
{"pmid": "4354029", "title": "Respiratory activation of 2,4-dinitrophenol-stimulated ATPase activity in plant mitochondria.", "content": "Respiratory activation of 2,4-dinitrophenol-stimulated ATPase activity in plant mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354029"}
{"pmid": "4354022", "title": "Suppurative perichondritis of the auricle.", "content": "Suppurative perichondritis of the auricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354022"}
{"pmid": "4354030", "title": "Energy dependent changes in the cytochromes of the mitochondrial respiratory chain.", "content": "Energy dependent changes in the cytochromes of the mitochondrial respiratory chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354030"}
{"pmid": "4354031", "title": "Interconversion of the A and B forms of ceramide trihexosidase from human plasma.", "content": "Interconversion of the A and B forms of ceramide trihexosidase from human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354031"}
{"pmid": "4354032", "title": "Nucleoside diphosphatase from pig liver: purification and some properties.", "content": "Nucleoside diphosphatase from pig liver: purification and some properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354032"}
{"pmid": "4354023", "title": "Management of nasopharyngeal angiofibroma.", "content": "Management of nasopharyngeal angiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354023"}
{"pmid": "4354033", "title": "Gadolinium asa probe of the alkaline earth and ATP-metal binding sites in pyruvate kinase.", "content": "Gadolinium asa probe of the alkaline earth and ATP-metal binding sites in pyruvate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354033"}
{"pmid": "4354034", "title": "Incorporation of glucosamine into rhodopsin in isolated bovine retina.", "content": "Incorporation of glucosamine into rhodopsin in isolated bovine retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354034"}
{"pmid": "4354035", "title": "Superoxide dismutase: a comparison of rate constants.", "content": "Superoxide dismutase: a comparison of rate constants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354035"}
{"pmid": "4354036", "title": "Immunological studies on glucose 6-phosphate dehydrogenase of rat liver.", "content": "Immunological studies on glucose 6-phosphate dehydrogenase of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354036"}
{"pmid": "4354039", "title": "Radiation therapy for cancer of the lung: previous experience and definition of current issues.", "content": "Radiation therapy for cancer of the lung: previous experience and definition of current issues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354039"}
{"pmid": "4354040", "title": "A clinical trial of cyclophosphamide (NSC-26271) and radiation therapy for oat cell carcinoma of the lung.", "content": "A clinical trial of cyclophosphamide (NSC-26271) and radiation therapy for oat cell carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354040"}
{"pmid": "4354041", "title": "Combination chemotherapy and radiation therapy for small cell carcinoma of the lung.", "content": "Combination chemotherapy and radiation therapy for small cell carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354041"}
{"pmid": "4354042", "title": "Should initial treatment of small cell carcinoma include systemic chemotherapy and brain irradiation?", "content": "Should initial treatment of small cell carcinoma include systemic chemotherapy and brain irradiation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354042"}
{"pmid": "4354043", "title": "Observer variability and reliability in lung cancer diagnosis.", "content": "Observer variability and reliability in lung cancer diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354043"}
{"pmid": "4354044", "title": "A follow-up survey of out-patients in a medical clinic for Africans at Harare Hospital in Rhodesia.", "content": "A follow-up survey of out-patients in a medical clinic for Africans at Harare Hospital in Rhodesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354044"}
{"pmid": "4354045", "title": "Arousing effects of trophic hormones in hibernating Citellus lateralis.", "content": "Arousing effects of trophic hormones in hibernating Citellus lateralis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354045"}
{"pmid": "4354046", "title": "Behr's syndrome: familial optic atrophy, spastic diplegia and ataxia.", "content": "Behr's syndrome: familial optic atrophy, spastic diplegia and ataxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354046"}
{"pmid": "4354047", "title": "The problem of the Lennox syndrome.", "content": "The problem of the Lennox syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354047"}
{"pmid": "4354050", "title": "Microbial transformation of cholesterol into coprostanol. Properties of a 3-oxo- 4-steroid-5 beta-reductase.", "content": "Microbial transformation of cholesterol into coprostanol. Properties of a 3-oxo- 4-steroid-5 beta-reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354050"}
{"pmid": "4354049", "title": "Stimulation of ribonucleic-acid synthesis in chick-embryo fibroblasts by exogenous adenosine 3':5'-monophosphate.", "content": "Stimulation of ribonucleic-acid synthesis in chick-embryo fibroblasts by exogenous adenosine 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354049"}
{"pmid": "4354051", "title": "Effect of pH on electron-paramagnetic-resonance spectra of ceruloplasmin.", "content": "Effect of pH on electron-paramagnetic-resonance spectra of ceruloplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354051"}
{"pmid": "4354053", "title": "Effect of Bordetella pertussis vaccine on plasma corticosterone level and on ACTH-induced corticosterone secretion in rats.", "content": "Effect of Bordetella pertussis vaccine on plasma corticosterone level and on ACTH-induced corticosterone secretion in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354053"}
{"pmid": "4354054", "title": "Electron spin resonance spectra of white, cardiac and various red skeletal muscles of the carp, Cyprinus carpio L.", "content": "Electron spin resonance spectra of white, cardiac and various red skeletal muscles of the carp, Cyprinus carpio L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354054"}
{"pmid": "4354056", "title": "Effect of prostaglandins on cyclic AMP concentrations in toad bladder and rat kidney.", "content": "Effect of prostaglandins on cyclic AMP concentrations in toad bladder and rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354056"}
{"pmid": "4354055", "title": "Shortened duration of drug-induced behavioral excitation in rats with septal lesions.", "content": "Shortened duration of drug-induced behavioral excitation in rats with septal lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354055"}
{"pmid": "4354057", "title": "Reaction of rabbit muscle apo-glyceraldehyde-3-P-dehydrogenase with pyridoxal-5'-phosphate.", "content": "Reaction of rabbit muscle apo-glyceraldehyde-3-P-dehydrogenase with pyridoxal-5'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354057"}
{"pmid": "4354058", "title": "The binding of divalent cations by purified gangliosides.", "content": "The binding of divalent cations by purified gangliosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354058"}
{"pmid": "4354059", "title": "Steroid metabolism in testis tissue. Concentrations of testosterone, pregnenolone and 5 -androst-16-en-3 -ol in normal and cryptorchid rat testis, and in isolated interstitial and tubular tissue.", "content": "Steroid metabolism in testis tissue. Concentrations of testosterone, pregnenolone and 5 -androst-16-en-3 -ol in normal and cryptorchid rat testis, and in isolated interstitial and tubular tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354059"}
{"pmid": "4354060", "title": "The characterization of glycolipids derived from long-chain polyprenols: chemical synthesis of  -D-mannopyranosyl dolichyl phosphate.", "content": "The characterization of glycolipids derived from long-chain polyprenols: chemical synthesis of  -D-mannopyranosyl dolichyl phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354060"}
{"pmid": "4354062", "title": "On the specificity of cyclic AMP action in Escherichia coli.", "content": "On the specificity of cyclic AMP action in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354062"}
{"pmid": "4354061", "title": "The unambiguous characterization of dolichol phosphate mannose as a product of mannosyl transferase in pig liver endoplasmic reticulum.", "content": "The unambiguous characterization of dolichol phosphate mannose as a product of mannosyl transferase in pig liver endoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354061"}
{"pmid": "4354063", "title": "Correlation between (3H)dexamethasone binding to a rat liver cytosol receptor protein and stimulation of RNA synthesis by glucocorticosteroids.", "content": "Correlation between (3H)dexamethasone binding to a rat liver cytosol receptor protein and stimulation of RNA synthesis by glucocorticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354063"}
{"pmid": "4354064", "title": "Cholesterol and phospholipid composition of mitochondria and microsomes isolated from morris hepatoma 5123 and rat liver.", "content": "Cholesterol and phospholipid composition of mitochondria and microsomes isolated from morris hepatoma 5123 and rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354064"}
{"pmid": "4354065", "title": "Stimulation of RNA synthesis in Cicer arietinum seedlings by cyclic 3':5' adenosine monophosphate.", "content": "Stimulation of RNA synthesis in Cicer arietinum seedlings by cyclic 3':5' adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354065"}
{"pmid": "4354068", "title": "Ganglioside patterns and phenotypic characteristics in a normal variant and a transformed back variant of a simian virus 40-induced hamster tumor cell line.", "content": "Ganglioside patterns and phenotypic characteristics in a normal variant and a transformed back variant of a simian virus 40-induced hamster tumor cell line. Ganglioside patterns of a cloned Simian virus 40- (SV40) induced hamster tumor cell (Cl(2)TSV(5)-S), its normal variant (Cl(2)TSV(5)-R) which are Cl(2)TSV(5)-S gradually adapted to grow in the presence of 2 microg/ml actinomycin D and exhibit certain normal phenotypic characteristics, and its back variant (Cl(2)TSV(5)-RR), which are Cl(2)TSV(5)-R cells grown in the absence of actinomycin D for more than 60 passages and which exhibit greater phenotypic similarity to Cl(2)TSV(5)-S cells, have been analyzed. All three cell lines contain N(acetylneuraminyl) galactosylglycosyl ceramide (hematoside, GM(3)), N-acetylgalactosaminyl (N-acetylneuraminyl) galactosylglucosyl ceramide (GM(2)), and a higher ganglioside tentatively identified as disialohematoside. However, Cl(2)TSV(5)-R have more GM(2) than Cl(2)TSV(5)-S whereas Cl(2)TSV(5)-RR contain an intermediate amount of GM(2). The amount of GM(2) is correlative with the activity of UDP-N-acetylgalactosamine: hematoside N-acetylgalactosaminyl transferase in the extract of the three cell lines and with their agglutination by wheat germ agglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354068"}
{"pmid": "4354071", "title": "Cell division, ciliary regeneration and cyclic AMP in a unicellular system.", "content": "Cell division, ciliary regeneration and cyclic AMP in a unicellular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354071"}
{"pmid": "4354069", "title": "Cell cycle-dependent changes in the surface membrane as detected with (3H)concanavalin A.", "content": "Cell cycle-dependent changes in the surface membrane as detected with (3H)concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354069"}
{"pmid": "4354070", "title": "The effect of environmental pH on the growth of normal and malignant cells.", "content": "The effect of environmental pH on the growth of normal and malignant cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354070"}
{"pmid": "4354072", "title": "Isolation and characterization of revertant cell lines. II. Growth control of a polyploid revertant line derived from SV40-transformed 3T3 mouse cells.", "content": "Isolation and characterization of revertant cell lines. II. Growth control of a polyploid revertant line derived from SV40-transformed 3T3 mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354072"}
{"pmid": "4354073", "title": "Post-transcriptional regulation of catalase synthesis in rat liver and hepatoma: factors activating and inhibiting catalase synthesis.", "content": "Post-transcriptional regulation of catalase synthesis in rat liver and hepatoma: factors activating and inhibiting catalase synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354073"}
{"pmid": "4354075", "title": "Defective cyclic adenosine-3', 5'-phosphate-phosphodiesterase regulation in morphogenetic mutants of Dictyostelium discoideum.", "content": "Defective cyclic adenosine-3', 5'-phosphate-phosphodiesterase regulation in morphogenetic mutants of Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354075"}
{"pmid": "4354074", "title": "Post-transcriptional regulation of catalase synthesis in rat liver and hepatoma: binding of inhibiting factor(s) with polyribosomes synthesizing catalase.", "content": "Post-transcriptional regulation of catalase synthesis in rat liver and hepatoma: binding of inhibiting factor(s) with polyribosomes synthesizing catalase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354074"}
{"pmid": "4354076", "title": "Synthesis of polyoma proteins in vitro.", "content": "Synthesis of polyoma proteins in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354076"}
{"pmid": "4354077", "title": "Length measurements of RNA synthesized in vitro by Escherichia coli RNA polymerase.", "content": "Length measurements of RNA synthesized in vitro by Escherichia coli RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354077"}
{"pmid": "4354078", "title": "SV40 DNA: quantitative conversion of closed circular to open circular form by an ethidium bromide-restricted endonuclease.", "content": "SV40 DNA: quantitative conversion of closed circular to open circular form by an ethidium bromide-restricted endonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354078"}
{"pmid": "4354080", "title": "Clostridium infection after intra-amniotic hypertonic saline injection for induced abortion.", "content": "Clostridium infection after intra-amniotic hypertonic saline injection for induced abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354080"}
{"pmid": "4354081", "title": "Australia antigen in liver tissue--an immunofluorescent and immunoelectron microscopic study.", "content": "Australia antigen in liver tissue--an immunofluorescent and immunoelectron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354081"}
{"pmid": "4354082", "title": "Effect of myoinositol and other polyols on  -galactosidase of mammarian tissues.", "content": "Effect of myoinositol and other polyols on  -galactosidase of mammarian tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354082"}
{"pmid": "4354084", "title": "Primary herpetic gingivostomatitis of adult onset. Clinical, laboratory, and ultrastructure correlations identifying viral etiology.", "content": "Primary herpetic gingivostomatitis of adult onset. Clinical, laboratory, and ultrastructure correlations identifying viral etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354084"}
{"pmid": "4354085", "title": "Effects of PGF2  infusion on human cortisol biosynthesis.", "content": "Effects of PGF2  infusion on human cortisol biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354085"}
{"pmid": "4354086", "title": "Effects of thyrotropin and N6,02'-dibutyryl cyclic 3'.5'-adenosine monophosphate on prostaglandin levels in thyroid.", "content": "Effects of thyrotropin and N6,02'-dibutyryl cyclic 3'.5'-adenosine monophosphate on prostaglandin levels in thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354086"}
{"pmid": "4354087", "title": "Antagonism of prostaglandin-promoted pituitary cyclic AMP accumulation and growth hormone secretion in vitro by 7-oxa-13-prostynoic acid.", "content": "Antagonism of prostaglandin-promoted pituitary cyclic AMP accumulation and growth hormone secretion in vitro by 7-oxa-13-prostynoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354087"}
{"pmid": "4354088", "title": "Prostaglandin release by the isolated perfused rabbit heart.", "content": "Prostaglandin release by the isolated perfused rabbit heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354088"}
{"pmid": "4354089", "title": "The effect of PGE1 on ADP-induced aggregation in refractory platelets.", "content": "The effect of PGE1 on ADP-induced aggregation in refractory platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354089"}
{"pmid": "4354090", "title": "Renomedullary interstitial cells (RIC), prostaglandins (PG) and the antihypertensive function of the kidney.", "content": "Renomedullary interstitial cells (RIC), prostaglandins (PG) and the antihypertensive function of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354090"}
{"pmid": "4354091", "title": "Differential inhibition by prostaglandins of the renal actions of pressor stimuli.", "content": "Differential inhibition by prostaglandins of the renal actions of pressor stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354091"}
{"pmid": "4354092", "title": "Significance of the effects of prostaglandins on renal and adrenal function in man.", "content": "Significance of the effects of prostaglandins on renal and adrenal function in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354092"}
{"pmid": "4354093", "title": "An essay: prostaglandins and toxemia of pregnancy.", "content": "An essay: prostaglandins and toxemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354093"}
{"pmid": "4354094", "title": "Inotropic effects of prostaglandins, fatty acids and adenosine phosphates on hypodynamic frog hearts.", "content": "Inotropic effects of prostaglandins, fatty acids and adenosine phosphates on hypodynamic frog hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354094"}
{"pmid": "4354099", "title": "Further studies on the antigenicity of some injectable tissue extracts.", "content": "Further studies on the antigenicity of some injectable tissue extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354099"}
{"pmid": "4354104", "title": "Evaluation of the effectiveness of treatment on adult height prognosis in disorders with advanced and retarded bone age. Height and height velocity related to chronological or to bone age.", "content": "Evaluation of the effectiveness of treatment on adult height prognosis in disorders with advanced and retarded bone age. Height and height velocity related to chronological or to bone age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354104"}
{"pmid": "4354105", "title": "Improvement of adult height prognosis in precocious puberty by cyproterone acetate.", "content": "Improvement of adult height prognosis in precocious puberty by cyproterone acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354105"}
{"pmid": "4354106", "title": "Uptake and degradation of 3H-phenoxymethylpenicillin in rat liver slices.", "content": "Uptake and degradation of 3H-phenoxymethylpenicillin in rat liver slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354106"}
{"pmid": "4354108", "title": "The effect of guanethidine pretreatment on transmission in the superior cervical ganglion.", "content": "The effect of guanethidine pretreatment on transmission in the superior cervical ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354108"}
{"pmid": "4354107", "title": "Cyclic AMP as a mediator of the relaxing action of papaverine, nitroglycerine, diazoxide and hydralazine in intestinal and vascular smooth muscle.", "content": "Cyclic AMP as a mediator of the relaxing action of papaverine, nitroglycerine, diazoxide and hydralazine in intestinal and vascular smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354107"}
{"pmid": "4354109", "title": "Pox in wild birds.", "content": "Pox in wild birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354109"}
{"pmid": "4354111", "title": "Toxemia of pregnancy. Mechanism and therapeutic management.", "content": "Toxemia of pregnancy. Mechanism and therapeutic management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354111"}
{"pmid": "4354112", "title": "An assessment of \"free\" and conjugated estriol in uncomplicated and complicated pregnancy plasma.", "content": "An assessment of \"free\" and conjugated estriol in uncomplicated and complicated pregnancy plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354112"}
{"pmid": "4354110", "title": "Abnormal biochemistry in myocardial failure.", "content": "Abnormal biochemistry in myocardial failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354110"}
{"pmid": "4354113", "title": "Trophoblastic disease in Uganda.", "content": "Trophoblastic disease in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354113"}
{"pmid": "4354114", "title": "Primary amenorrhea: a simplified approach to diagnosis.", "content": "Primary amenorrhea: a simplified approach to diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354114"}
{"pmid": "4354115", "title": "Clinical and metabolic features of anorexia nervosa.", "content": "Clinical and metabolic features of anorexia nervosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354115"}
{"pmid": "4354117", "title": "Exercise of normal muscle: biochemical effects.", "content": "Exercise of normal muscle: biochemical effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354117"}
{"pmid": "4354119", "title": "Fluorescence studies on polyoma virus.", "content": "Fluorescence studies on polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354119"}
{"pmid": "4354118", "title": "Complementation of theta-toxinogenicity between mutants of two groups of Clostridium perfringens.", "content": "Complementation of theta-toxinogenicity between mutants of two groups of Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354118"}
{"pmid": "4354116", "title": "Carcinoma of the extrahepatic biliary tract.", "content": "Carcinoma of the extrahepatic biliary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354116"}
{"pmid": "4354120", "title": "A \"spot-infection technique\" for titration and neutralization of poliovirus.", "content": "A \"spot-infection technique\" for titration and neutralization of poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354120"}
{"pmid": "4354121", "title": "Serial propagation of varicella virus in primary rabbit kidney cells.", "content": "Serial propagation of varicella virus in primary rabbit kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354121"}
{"pmid": "4354122", "title": "Influence of fasting and hemin on microsomal cytochromes and enzymes.", "content": "Influence of fasting and hemin on microsomal cytochromes and enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354122"}
{"pmid": "4354123", "title": "Interaction of cytochrome c with lipid monolayers.", "content": "Interaction of cytochrome c with lipid monolayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354123"}
{"pmid": "4354124", "title": "Characterisation of the surface of bovine milk fat globule membrane using microelectrophoresis.", "content": "Characterisation of the surface of bovine milk fat globule membrane using microelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354124"}
{"pmid": "4354125", "title": "The isolation and characterization of plasma membrane from cultured cells. V. The chemical composition of plasma membranes isolated from chicken tumors initiated with virus-transformed cells.", "content": "The isolation and characterization of plasma membrane from cultured cells. V. The chemical composition of plasma membranes isolated from chicken tumors initiated with virus-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354125"}
{"pmid": "4354126", "title": "Isolation of plasma membranes from Ehrlich ascites tumor cells. Influence of amino acids on (Na++K+)-ATPase and K+-stimulated phosphatase.", "content": "Isolation of plasma membranes from Ehrlich ascites tumor cells. Influence of amino acids on (Na++K+)-ATPase and K+-stimulated phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354126"}
{"pmid": "4354127", "title": "Binding of proteins to mycoplasma membranes.", "content": "Binding of proteins to mycoplasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354127"}
{"pmid": "4354128", "title": "Mobility of spin-labelled sulfhydryl sites in excitable tissue.", "content": "Mobility of spin-labelled sulfhydryl sites in excitable tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354128"}
{"pmid": "4354129", "title": "Preparation of inverted plasma membrane vesicles from isolated adipocytes.", "content": "Preparation of inverted plasma membrane vesicles from isolated adipocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354129"}
{"pmid": "4354130", "title": "Spin labels as enzyme substrates. Heterogeneous lipid distribution in liver microsomal membranes.", "content": "Spin labels as enzyme substrates. Heterogeneous lipid distribution in liver microsomal membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354130"}
{"pmid": "4354131", "title": "The effects of long-chain alcohols on membrane lipids and the (Na++K+)-ATPase.", "content": "The effects of long-chain alcohols on membrane lipids and the (Na++K+)-ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354131"}
{"pmid": "4354132", "title": "Deoxycytidine uptake by isolated membrane vesicles from Escherichia coli K 12.", "content": "Deoxycytidine uptake by isolated membrane vesicles from Escherichia coli K 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354132"}
{"pmid": "4354133", "title": "The purification of membrane-associated tumour antigens by preparative polyacrylamide gel electrophoresis.", "content": "The purification of membrane-associated tumour antigens by preparative polyacrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354133"}
{"pmid": "4354134", "title": "Dibutyryl cyclic adenosine monophosphate enhancement of alpha-methyl-D-glucoside accumulation by kidney cortex slices.", "content": "Dibutyryl cyclic adenosine monophosphate enhancement of alpha-methyl-D-glucoside accumulation by kidney cortex slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354134"}
{"pmid": "4354136", "title": "Alveolar adenocarcinoma complicating pulmonary fibrosis due to mitral stenosis.", "content": "Alveolar adenocarcinoma complicating pulmonary fibrosis due to mitral stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354136"}
{"pmid": "4354135", "title": "Effect of guanosine 3':5'-monophosphate on the hydroosmotic activity of adenosine 3':5'-monophosphate in toad urinary bladder.", "content": "Effect of guanosine 3':5'-monophosphate on the hydroosmotic activity of adenosine 3':5'-monophosphate in toad urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354135"}
{"pmid": "4354139", "title": "Factors affecting proton magnetic resonance linewidths of water in several rat tissues.", "content": "Factors affecting proton magnetic resonance linewidths of water in several rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354139"}
{"pmid": "4354140", "title": "The control of phosphorylase kinase phosphatase by \"second site phosphorylation\"; a new form of enzyme regulation.", "content": "The control of phosphorylase kinase phosphatase by \"second site phosphorylation\"; a new form of enzyme regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354140"}
{"pmid": "4354141", "title": "Isolation of acidic lipoproteins from brain chromatin. Their relation to the acidic nonhistone proteins.", "content": "Isolation of acidic lipoproteins from brain chromatin. Their relation to the acidic nonhistone proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354141"}
{"pmid": "4354142", "title": "Correlation of substrate specificity of cAMP-phosphodiesterase in Dictyostelium discoideum with chemotactic activity of cAMP-analogues.", "content": "Correlation of substrate specificity of cAMP-phosphodiesterase in Dictyostelium discoideum with chemotactic activity of cAMP-analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354142"}
{"pmid": "4354143", "title": "Stimulation by prostaglandin E1 of adenosine 3':5'-cyclic monophosphate formation in neuroblastoma cells in the presence of phosphodiesterase inhibitors.", "content": "Stimulation by prostaglandin E1 of adenosine 3':5'-cyclic monophosphate formation in neuroblastoma cells in the presence of phosphodiesterase inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354143"}
{"pmid": "4354145", "title": "Studies of carcinoembryonic antigen activity of whole and extracted serum in ulcerative colitis.", "content": "Studies of carcinoembryonic antigen activity of whole and extracted serum in ulcerative colitis. The present study has used a microradioimmunoassay to detect carcinoembryonic antigen(s) (CEA) in whole and extracted serum in 77 patients with ulcerative colitis, two of whom had coexisting colonic carcinoma, and 69 patients with carcinoma of the colon or rectum. Taking 5 ng/ml as the level of positivity, the CEA assay on whole serum showed positive results in patients with ;active' ulcerative colitis (15 of 17) but not in those with ;inactive' disease (0 of 23). In two patients, levels fell during drug-induced remission. Our results also indicated that a positive result for CEA on extracted serum was associated with carcinomatous changes in ulcerative colitis in contrast to uncomplicated ulcerative colitis in which positive results were obtained only with whole serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354145"}
{"pmid": "4354146", "title": "Hypersecretion of zymogen granules in the pathogenesis of cystic fibrosis.", "content": "Hypersecretion of zymogen granules in the pathogenesis of cystic fibrosis. In the submandibular saliva of 10 cystic fibrosis subjects and 10 controls the turbidity and elevated calcium, protein, and amylase concentrations of the cystic fibrosis secretions, and precipitation of calcium and phosphate in a ratio consistent with hydroxyapatite have been confirmed. By electron microscopy the centrifuged deposits of the cystic fibrosis saliva were seen to be composed predominantly of round or oval subcellular corpuscles. By comparison with submandibular gland, these corpuscles have been identified as inclusion bodies (spherules) from within zymogen granules. Hydroxyapatite crystals formed on standing in the cystic fibrosis saliva. Polyacrylamide gel disc electrophoresis of the cystic fibrosis centrifuged deposits showed five bands, one of which, band 4, was more prominent in the deposit than in the supernatant gels. Comparisons have been made between these results and other studies and have shown (1) elevated calcium and protein in cystic fibrosis exocrine secretions; (2) simultaneous secretion of calcium and enzymes from salivary glands, stomach, and pancreas; and (3) increased salivary secretion of calcium and protein in response to parasympathomimetic and sympathomimetic drugs. Hypersecretion of calcium-containing zymogen granules is postulated as the cause of obstruction in cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354146"}
{"pmid": "4354147", "title": "Studies on the mechanism of the priming effect of interferon on interferon production by cell cultures exposed to poly(rI)-poly(rC).", "content": "Studies on the mechanism of the priming effect of interferon on interferon production by cell cultures exposed to poly(rI)-poly(rC). Interferon induction by poly(rI).poly(rC) in primary rabbit kidney and mouse L-929 cell cultures was markedly increased if the cells were previously treated with homologous interferon. This priming effect has been established with different times of exposure of the cells to poly(rI).poly(rC), and was most pronounced for short pulses of contact of the polynucleotide with the cells (10 s, 1 min). Treatment of the cells with pancreatic ribonuclease immediately after their exposure to poly(rI).poly(rC) brought about a relatively greater reduction of the interferon response in interferon-primed cells than it did in unprimed cell cultures. Priming of the cells with interferon did not increase cell-binding of poly(rI).poly(rC), whether this cell-binding was measured quantitatively (by radioactivity, upon exposure of the cells to radiolabeled polymer) or qualitatively (by antiviral activity, by assaying the cell extract for virus plaque reduction). Similarly, interferon priming did not alter the sensitivity of cell-associated poly(rI).poly(rC) to extraneous ribonuclease treatment. Finally, priming with interferon did not decrease the rate of degradation of cell-bound poly(rI).poly(rC) by cellular nucleases nor did it increase the anti-nuclease potency of the cells. The exact mechanism by which previous exposure of the cells to interferon enhances subsequent interferon production, induced by either synthetic polynucleotides or viruses, has not yet been resolved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354147"}
{"pmid": "4354138", "title": "Urinary corticosteriod and diphenylhydantoin metabolite patterns in neonates exposed to anticonvulsant drugs in utero.", "content": "Urinary corticosteriod and diphenylhydantoin metabolite patterns in neonates exposed to anticonvulsant drugs in utero.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354138"}
{"pmid": "4354149", "title": "Role of zinc in the production of Clostridium perfringens alpha toxin.", "content": "Role of zinc in the production of Clostridium perfringens alpha toxin. Clostridium perfringens was found to produce alpha toxin in a synthetic medium containing zinc; in medium containing no zinc, a little toxin was detected in the early logarithmic phase of growth and it disappeared rapidly. No intracellular accumulation of alpha toxin protein occurred whether or not zinc was present in the medium. In zinc-deficient medium, the organisms produced and released into the surrounding medium the protein specifically precipitable with alpha antitoxin in an amount comparable to that of alpha toxin produced in the zinc-containing medium. The protein combined rapidly in some unknown way with zinc to form the active and stable alpha toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354149"}
{"pmid": "4354137", "title": "Inhibition by lithium of prostaglandin E1 and norepinephrine effects on cyclic adenosine monophosphate production in human platelets.", "content": "Inhibition by lithium of prostaglandin E1 and norepinephrine effects on cyclic adenosine monophosphate production in human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354137"}
{"pmid": "4354150", "title": "Interferon responsiveness of rabbit synovial cells and chondrocytes.", "content": "Interferon responsiveness of rabbit synovial cells and chondrocytes. Rabbit synovial cells (SC), articular chondrocytes (AC), and epiphyseal (EC) chondrocytes were grown in vitro. A portion of the spectrum of human pathogenic viruses infective for the cells was determined. Responses of the cells to different viruses or a chemical inducer of interferon varied, with EC responding vigorously and with high titers, AC responding only to chemical inducer and influenza virus, and SC producing no detectable interferon. All cells supported prolonged growth of influenza virus without showing microscopic cytopathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354150"}
{"pmid": "4354148", "title": "Inhibition of enzymes by human salivary immunoglobulin A.", "content": "Inhibition of enzymes by human salivary immunoglobulin A. Human whole saliva inhibited bacterial neuraminidases and the inhibition was found to reside in the salivary IgA fraction. Further, salivary immunoglobulin (Ig)A inhibited various bacterial enzymes and toxins: neuraminidases from Streptococcus mitis, Streptococcus sanguis, and Clostridium perfringens, hyaluronidase and chondroitin sulfatase from oral bacteria, diphtheria toxin, and streptolysin O. The inhibitory activity of salivary IgA did not correlate with that of serum on the basis of minimum inhibitory dose. A small amount of salivary IgA was required to inhibit oral bacterial neuraminidases, whereas a large amount was required to inhibit other bacterial neuraminidase. Therefore, it is concluded that the absence of neuraminidase activity of oral bacteria in whole saliva may be due to specific inhibition by salivary IgA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354148"}
{"pmid": "4354152", "title": "Visna virus infection of sheep and human cells in vitro--an ultrastructural study.", "content": "Visna virus infection of sheep and human cells in vitro--an ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354152"}
{"pmid": "4354151", "title": "Ultrastructural characterization of genome of epizootic hemorrhagic disease virus.", "content": "Ultrastructural characterization of genome of epizootic hemorrhagic disease virus. Purified epizootic hemorrhagic disease (EHD) virus preparations were treated with urea and sodium perchlorate. The viral ribonucleic acid (RNA) released when spread on protein monolayers according to the Kleinschmidt technique was examined by rotary shadow-casting electron microscopy. The viral RNA released by urea treatment had filaments which frequently formed three to five loop-shaped figures of varied length. In 80% of the virus particles the lengths of the viral RNA released were 2.5 to 4.5 mum. The sodium perchlorate-released viral nucleic acid also appeared linear, and about 70% had lengths of 0.1 to 2.0 mum, the longest filament measuring 5.8 mum. Evidence was obtained that EHD virus contains double-stranded RNA as its genetic material and the molecular weight of the EHD viral RNA was calculated to be 12.2 x to 10(6) to 15.1 x 10(6) daltons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354151"}
{"pmid": "4354153", "title": "The effect of x-radiation on spermatogenesis and the fertility of Schistocerca gregaria (Forsk.).", "content": "The effect of x-radiation on spermatogenesis and the fertility of Schistocerca gregaria (Forsk.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354153"}
{"pmid": "4354154", "title": "Glycerolipid synthesis in rat adipose tissue. II. Properties and distribution of phosphatidate phosphatase.", "content": "Glycerolipid synthesis in rat adipose tissue. II. Properties and distribution of phosphatidate phosphatase. The properties and subcellular distribution of phosphatidate phosphatase (EC 3.1.3.4) from adipose tissue have been investigated. The enzyme was assayed using both aqueous phosphatidate and membrane-bound phosphatidate as substrates. When measured with aqueous substrate, activity was detected in the mitochondria, the microsomes, and the soluble fraction. Mg(2+) at low concentration stimulated the phosphatidate phosphatase from soluble and microsomal fractions but had no effect on the mitochondrial phosphatidate phosphatase. At higher concentration Mg(2+) was inhibitory. In the presence of Mg(2+), the phosphatidate phosphatase from soluble and microsomal fractions was active against membrane-bound phosphatidate. No activity was demonstrated with membrane-bound substrate in the absence of Mg(2+). Mitochondria did not contain activity toward the membrane-bound substrate. The rate of utilization of aqueous phosphatidate was always higher than that of membrane-bound substrate. These results indicate that there are at least two different phosphatidate phosphatases in adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354154"}
{"pmid": "4354155", "title": "A regional survey of myelin development: some compositional and metabolic aspects.", "content": "A regional survey of myelin development: some compositional and metabolic aspects. A survey of differences in composition and metabolism of myelin from five areas of the central nervous system was made in brain and spinal cord slices of the rat from 20 days to 20 months postnatal age. Purified myelin from the forebrain areas showed a composition characteristic of immaturity longer than did myelin from the hindbrain and spinal cord. The trend of chemical maturity is in agreement with the anatomical observations that myelination begins in the hindbrain and proceeds rostrally. Myelin recovery per 100-mg slice increased continually from 20 days to 20 months of age, while the uptake of [1-(14)C]acetate into myelin lipid and of [1-(14)C]leucine into myelin protein decreased precipitously with age. Taking into account the continuous increase in myelin during maturation, a calculation was made of the total amount of incorporation of labeled material into lipids or proteins per 100-mg slice for each region at each age. The metabolic characteristics of myelin from the cerebral cortex (including the corpus callosum), the thalamic area, and the cerebellum were very similar, while myelin from brainstem and spinal cord was metabolically more active, especially at the early ages. Synthesis of lipid in the myelin sheath represents about 50% of the lipid synthesis of the whole brain and about 75% of that of the spinal cord. The proportion of myelin-related protein synthesis is much less, probably less than 10% of the protein synthesis occurring in whole brain and about 15% of that in the spinal cord except at early ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354155"}
{"pmid": "4354156", "title": "Regulation by dietary choline of hepatic fatty acid synthetase in the rat.", "content": "Regulation by dietary choline of hepatic fatty acid synthetase in the rat. Fatty acid synthetase activity was measured in the high-speed supernatant fraction of liver homogenates from rats fed a semisynthetic diet low in lipotropic factors. If choline was omitted from the diet, a significant increase of fatty acid synthetase activity was observed after two feedings of the deficient diet. Compared with controls, the increase of fatty acid synthetase activity was of a magnitude that could account for the amount of triglyceride accumulating in the hepatic floating lipid fraction. Gas-liquid chromatographic analysis of the floating lipid triglycerides showed an increased content of palmitic acid due to choline deficiency; this increase could be predicted from the increased fatty acid synthetase activity and its known characteristic yield of palmitic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354156"}
{"pmid": "4354157", "title": "A hypothesis relating lymphocyte phosphorylation and transport of ara-C (cytarabine) to its antiviral activity.", "content": "A hypothesis relating lymphocyte phosphorylation and transport of ara-C (cytarabine) to its antiviral activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354157"}
{"pmid": "4354158", "title": "Diffusion models for firing of a neuron with varying threshold.", "content": "Diffusion models for firing of a neuron with varying threshold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354158"}
{"pmid": "4354159", "title": "Contribution of the free energy of mixing of hydrophobic side chains to the stability of the tertiary structure of proteins.", "content": "Contribution of the free energy of mixing of hydrophobic side chains to the stability of the tertiary structure of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354159"}
{"pmid": "4354160", "title": "Clostridium welchii enterocolitis in arteriosclerotic patients.", "content": "Clostridium welchii enterocolitis in arteriosclerotic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354160"}
{"pmid": "4354161", "title": "Application of radioimmunoassay to the renin-angiotensin system and to aldosterone.", "content": "Application of radioimmunoassay to the renin-angiotensin system and to aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354161"}
{"pmid": "4354162", "title": "Peptide hormone binding to receptors: a review of direct studies in vitro.", "content": "Peptide hormone binding to receptors: a review of direct studies in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354162"}
{"pmid": "4354163", "title": "Measurement of steroid hormones using intracellular receptor proteins.", "content": "Measurement of steroid hormones using intracellular receptor proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354163"}
{"pmid": "4354164", "title": "Application of competitive ligand-binding radioassays to the nucleotides.", "content": "Application of competitive ligand-binding radioassays to the nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354164"}
{"pmid": "4354165", "title": "The impact of radioimmunoassay on our understanding of human adrenal physiology.", "content": "The impact of radioimmunoassay on our understanding of human adrenal physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354165"}
{"pmid": "4354167", "title": "Measurements of renin-angiotensin-aldosterone.", "content": "Measurements of renin-angiotensin-aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354167"}
{"pmid": "4354166", "title": "Radioimmunoassay methodology: application to problems of heterogeneity of peptide hormones.", "content": "Radioimmunoassay methodology: application to problems of heterogeneity of peptide hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354166"}
{"pmid": "4354168", "title": "Role of the renal lymph in relation to the renin-angiotensin system in the rat.", "content": "Role of the renal lymph in relation to the renin-angiotensin system in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354168"}
{"pmid": "4354169", "title": "Thyrotropin- and prostaglandin E2-responsive adenyl cyclase in thyroid plasma membranes.", "content": "Thyrotropin- and prostaglandin E2-responsive adenyl cyclase in thyroid plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354169"}
{"pmid": "4354170", "title": "Gelatin: a poor substrate for a mammalian collegenase.", "content": "Gelatin: a poor substrate for a mammalian collegenase. A rabbit tumor collagenase was purified more than 5000-fold. In this form it degrades native collagen in helical conformation at 37 degrees C, pH 7.6, into two fragments, but it had little capacity to cleave gelatin, an indication of the importance of higher-order structure of substrate for this enzyme in pure form. It is likely that, in vivo, enzymes other than collagenase degrade gelatin polypeptides produced by primary collagenolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354170"}
{"pmid": "4354171", "title": "Nerve growth factor: relationship to the cyclic AMP system of sensory ganglia.", "content": "Nerve growth factor: relationship to the cyclic AMP system of sensory ganglia. Nerve growth factor and N(6),O(2)' dibutyryl adenosine 3',5'-monophosphate both stimulate neurite elongation by explanted ganglia. However, the addition of nerve growth factor does not lead to increased amounts of adenosine 3',5'-monophosphate in intact ganglia, nor does it stimulate adenylate cyclase activity in broken ganglia cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354171"}
{"pmid": "4354172", "title": "Gamma-aminobutyric acid antagonism in visual cortex: different effects on simple, complex, and hypercomplex neurons.", "content": "Gamma-aminobutyric acid antagonism in visual cortex: different effects on simple, complex, and hypercomplex neurons. Intravenous bicuculline was used to examine how removing gamma-aminobutyric acid-mediated inhibition affects the visual response properties of single cortical neurons. Simple neurons were depressed and complex neurons showed increase in the vigor and range of responses. Hypercomplex cells were no longer inhibited by elongated stimuli. The results are consistent with present evidence concerning the origin and distribution of inhibitory connections within the cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354172"}
{"pmid": "4354174", "title": "Mutations in immunoglobulin-producing mouse myeloma cells.", "content": "Mutations in immunoglobulin-producing mouse myeloma cells. Three mouse myeloma cell lines were cloned in soft agar and screened by an antiserum overlay method for variants defective in secretion of the myeloma protein. Variants that had lost the capacity to synthesize heavy chains arose spontaneously at a high rate of about 10(-3) per cell per generation. Such variants lost the capacity to produce light chains at a similarly high rate. After cells were treated with the acridine half mustard ICR-191, variants occurred with an even higher incidence, and some of these synthesized heavy chains differing from that of the parent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354174"}
{"pmid": "4354175", "title": "Neural micro- and macrostates.", "content": "Neural micro- and macrostates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354175"}
{"pmid": "4354173", "title": "Estrogen-receptor interaction.", "content": "Estrogen-receptor interaction. The interaction of estradiol with uterine cells involves the association of the hormone with an extranuclear receptor protein, followed by temperature dependent translocation of the resulting complex to the nucleus. During this process, the steroid binding unit of the protein undergoes an alteration, called \"receptor transformation,\" that can be recognized by an increase in its sedimentation rate from 3.8S to 5.2S, and by its acquisition of the ability to bind to isolated uterine nuclei and to alleviate a tissue specific deficiency in the RNA synthesizing capacity of such nuclei. Receptor transformation can be effected in the absence of nuclei by warming uterine cytosol with estradiol. This preparation of transformed complex resembles that extracted from nuclei both in its sedimentation rate (5.3S) and in its ability to bind to uterine nuclei and augment RNA synthesis, properties that are not shown by the native complex. It is proposed that receptor transformation is an important step in estrogen action and that a principal role of the hormone is to induce conversion of the receptor protein to a biochemically functional form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354173"}
{"pmid": "4354178", "title": "Mesotheliomata in rats after inoculation with asbestos and other materials.", "content": "Mesotheliomata in rats after inoculation with asbestos and other materials. Four experiments in which SPF Wistar rats were inoculated intrapleurally with asbestos or other materials are described. Mesotheliomata were observed in a considerable proportion of animals with all the samples of asbestos used and with a sample of brucite. A few were produced with synthetic aluminium silicate fibres and single ones with barium sulphate, glass powder and aluminium oxide. The risk of developing a mesothelioma at a given time after injection was approximately proportional to the dose. Of the UICC standard reference samples, crocidolite was the most carcinogenic and removal of the oils by benzene extraction did not alter the carcinogenicity of these samples. Chemical properties also seem unlikely to be the main factor producing mesotheliomata but the results support the hypothesis that the finer fibres are the more carcinogenic, and this is additional to the known aerodynamic advantage which the finer fibres have in penetrating to the periphery of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354178"}
{"pmid": "4354180", "title": "Pediatric antimicrobial therapy IV.", "content": "Pediatric antimicrobial therapy IV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354180"}
{"pmid": "4354179", "title": "Human polyomavirus infection in renal allograft recipients.", "content": "Human polyomavirus infection in renal allograft recipients. Cytological and virological studies on 74 patients with functioning renal allografts were undertaken to detect polyomavirus infection of the renal tract. Ten patients (13.5%) were excreting polyomavirus. Virus particles were seen in the electron microscope in urine samples from eight patients. B.K. polyomavirus was isolated from four patients. Infection with a different polyomavirus was probable in one patient. Virus isolation was most readily achieved when large numbers of intact virus particles were seen in the urine. Patients who were excreting large amounts of polyomavirus shed numerous inclusion-bearing cells which could be detected by cytology. A serological study showed that the prevalence of B.K. antibody was similar to that found in the general population and 38% of this series of transplant patients had evidence of active infection with B.K. virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354179"}
{"pmid": "4354184", "title": "Growth impairment following irradiation in one of a pair of monozygotic twins.", "content": "Growth impairment following irradiation in one of a pair of monozygotic twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354184"}
{"pmid": "4354185", "title": "The effects of inactivity, programmed stimulation, and denervation on the histochemistry of skeletal muscle fiber types.", "content": "The effects of inactivity, programmed stimulation, and denervation on the histochemistry of skeletal muscle fiber types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354185"}
{"pmid": "4354187", "title": "Effects of atropine, reserpine, 6-hydroxydopamine, and handling on seizure development in the rat.", "content": "Effects of atropine, reserpine, 6-hydroxydopamine, and handling on seizure development in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354187"}
{"pmid": "4354186", "title": "Drug inhibition of PAH transport from cerobrospinal fluid in rabbits.", "content": "Drug inhibition of PAH transport from cerobrospinal fluid in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354186"}
{"pmid": "4354188", "title": "Acute antiepileptic effects of 9-tetrahydrocannabinol in rats with kindled seizures.", "content": "Acute antiepileptic effects of 9-tetrahydrocannabinol in rats with kindled seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354188"}
{"pmid": "4354176", "title": "Evaluation of recovery from nondepolarizing neuromuscular block, using a digital neuromuscular transmission analyzer: preliminary report.", "content": "Evaluation of recovery from nondepolarizing neuromuscular block, using a digital neuromuscular transmission analyzer: preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354176"}
{"pmid": "4354189", "title": "Magnetic resonance methods in membrane research.", "content": "Magnetic resonance methods in membrane research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354189"}
{"pmid": "4354190", "title": "Adenyl cyclase activity in non-nucleated red blood cells: evidence for its localization in the reticulocytes.", "content": "Adenyl cyclase activity in non-nucleated red blood cells: evidence for its localization in the reticulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354190"}
{"pmid": "4354192", "title": "Depolarization by acetylcholine (ACH activation of triphosphoinositide phosphomonoesterase).", "content": "Depolarization by acetylcholine (ACH activation of triphosphoinositide phosphomonoesterase).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354192"}
{"pmid": "4354191", "title": "Intracellular enzymes in renal lymph as a measure of anoxic injury of the kidney.", "content": "Intracellular enzymes in renal lymph as a measure of anoxic injury of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354191"}
{"pmid": "4354193", "title": "Alkylating esters. VII. The metabolism of iso-propyl methanesulphonate and iso-propyl iodide in the rat.", "content": "Alkylating esters. VII. The metabolism of iso-propyl methanesulphonate and iso-propyl iodide in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354193"}
{"pmid": "4354194", "title": "Ineffectiveness of adrenocorticosteroids and adrenocorticotropin in altering Na-K currents in squid giant axon.", "content": "Ineffectiveness of adrenocorticosteroids and adrenocorticotropin in altering Na-K currents in squid giant axon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354194"}
{"pmid": "4354195", "title": "A quantitative investigation of the response to injury of the central nervous system of rats treated with ACTH and triiodothyronine.", "content": "A quantitative investigation of the response to injury of the central nervous system of rats treated with ACTH and triiodothyronine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354195"}
{"pmid": "4354196", "title": "On mitochondrial inclusions in granulosa lutein cells of pregnant cows.", "content": "On mitochondrial inclusions in granulosa lutein cells of pregnant cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354196"}
{"pmid": "4354197", "title": "Inhibition of cell proliferation caused by oncogenic DNA-polyoma virus.", "content": "Inhibition of cell proliferation caused by oncogenic DNA-polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354197"}
{"pmid": "4354198", "title": "Induction of active immune state by multinucleate tumour cells in mice.", "content": "Induction of active immune state by multinucleate tumour cells in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354198"}
{"pmid": "4354199", "title": "Splenic cellular responses in vitro after tumour-immunization.", "content": "Splenic cellular responses in vitro after tumour-immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354199"}
{"pmid": "4354201", "title": "Hair tissue in the diagnosis of marasmus and kwashiorkor.", "content": "Hair tissue in the diagnosis of marasmus and kwashiorkor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354201"}
{"pmid": "4354203", "title": "Congenital multiple hemivertebrae.", "content": "Congenital multiple hemivertebrae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354203"}
{"pmid": "4354202", "title": "Bone case of the month: fibrosarcoma.", "content": "Bone case of the month: fibrosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354202"}
{"pmid": "4354204", "title": "Perspective: mental health.", "content": "Perspective: mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354204"}
{"pmid": "4354205", "title": "Characterization of herpes simplex virus-induced deoxyribonucleic acid polymerase.", "content": "Characterization of herpes simplex virus-induced deoxyribonucleic acid polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354205"}
{"pmid": "4354207", "title": "N-methyl-2-anilinonaphthalene-6-sulfonyl peptides as fluorescent probes for pepsin-substrate interaction.", "content": "N-methyl-2-anilinonaphthalene-6-sulfonyl peptides as fluorescent probes for pepsin-substrate interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354207"}
{"pmid": "4354206", "title": "Phosphorylation of lysine-rich histone in the isolated perfused rat liver. Effects of glucagon, cyclic adenosine 3':5'-monophosphate, and insulin.", "content": "Phosphorylation of lysine-rich histone in the isolated perfused rat liver. Effects of glucagon, cyclic adenosine 3':5'-monophosphate, and insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354206"}
{"pmid": "4354208", "title": "Nucleotide sequence determination of bacteriophage T4 leucine transfer ribonucleic acid.", "content": "Nucleotide sequence determination of bacteriophage T4 leucine transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354208"}
{"pmid": "4354210", "title": "Electron paramagnetic resonance studies of manganese (II)-pyruvate kinase-substrate complexes.", "content": "Electron paramagnetic resonance studies of manganese (II)-pyruvate kinase-substrate complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354210"}
{"pmid": "4354209", "title": "Mechanisms regulating the concentration and the conformation of progesterone receptor(s) in the uterus.", "content": "Mechanisms regulating the concentration and the conformation of progesterone receptor(s) in the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354209"}
{"pmid": "4354211", "title": "Characterization of a proposed oxytocin receptor in rat mammary gland.", "content": "Characterization of a proposed oxytocin receptor in rat mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354211"}
{"pmid": "4354212", "title": "Substrate-dependent, thiol-dependent, inactivation of pig brain nicotinamide adenine dinucleotide glycohydrolase.", "content": "Substrate-dependent, thiol-dependent, inactivation of pig brain nicotinamide adenine dinucleotide glycohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354212"}
{"pmid": "4354213", "title": "Malate dehydrogenase. XII. Initial rate kinetic studies of substrate activation of porcine mitochondrial enzyme by malate.", "content": "Malate dehydrogenase. XII. Initial rate kinetic studies of substrate activation of porcine mitochondrial enzyme by malate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354213"}
{"pmid": "4354214", "title": "Cell-free collagen synthesis on membrane-bound polysomes of chick embryo connective tissue and the localization of prolyl hydroxylase on the polysome-membrane complex.", "content": "Cell-free collagen synthesis on membrane-bound polysomes of chick embryo connective tissue and the localization of prolyl hydroxylase on the polysome-membrane complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354214"}
{"pmid": "4354215", "title": "Affinity chromatography and the purification of estrogen receptors.", "content": "Affinity chromatography and the purification of estrogen receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354215"}
{"pmid": "4354216", "title": "Pituitary growth retardation in children.", "content": "Pituitary growth retardation in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354216"}
{"pmid": "4354217", "title": "The effect of high-frequency vibration on the activity of some enzymes (cytochrome oxidase, talase, peroxidase) participating in biological oxidation in experiment.", "content": "The effect of high-frequency vibration on the activity of some enzymes (cytochrome oxidase, talase, peroxidase) participating in biological oxidation in experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354217"}
{"pmid": "4354219", "title": "Immunogenic properties of formalin herpes antigen prepared from cell cultures.", "content": "Immunogenic properties of formalin herpes antigen prepared from cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354219"}
{"pmid": "4354218", "title": "Reaction of mice on infection with mycoplasma and leukosis viruses.", "content": "Reaction of mice on infection with mycoplasma and leukosis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354218"}
{"pmid": "4354220", "title": "Pituitary apoplexy in a child. Case report.", "content": "Pituitary apoplexy in a child. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354220"}
{"pmid": "4354225", "title": "Attenuation of the morphine EEG continuum following a repeat dose within 16 days: delayed tolerance in the rat.", "content": "Attenuation of the morphine EEG continuum following a repeat dose within 16 days: delayed tolerance in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354225"}
{"pmid": "4354226", "title": "Behavioural effects of dibutyryl cyclic 3',5' AMP, noradrenaline and cyclic 3',5' AMP in rats.", "content": "Behavioural effects of dibutyryl cyclic 3',5' AMP, noradrenaline and cyclic 3',5' AMP in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354226"}
{"pmid": "4354228", "title": "Isolation of a neurotropic type C virus.", "content": "Isolation of a neurotropic type C virus. A neurogenic paralysis of the lower limb can be induced and serially transmitted in mice by a nontransforming type C virus strain that originated in an embryo of a wild mouse. The virus exerted a neurotropic effect on the anterior horn neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354228"}
{"pmid": "4354229", "title": "Regulation of phosphodiesterase synthesis: requirement for cyclic adenosine monophosphate-dependent protein kinase.", "content": "Regulation of phosphodiesterase synthesis: requirement for cyclic adenosine monophosphate-dependent protein kinase. Endogenous cyclic adenosine monophosphate (AMP) and its dibutyryl derivative increase cyclic AMP phosphodiesterase activity in cultured lymphoma cells. This effect is prevented by cycloheximide. A variant population of cells deficient in cyclic AMP-dependent protein kinase contains lower basal phosphodiesterase activity, which cannot be induced by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354229"}
{"pmid": "4354230", "title": "Comparative studies on bacterial 5S ribosomal RNA.", "content": "Comparative studies on bacterial 5S ribosomal RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354230"}
{"pmid": "4354231", "title": "Protein binding of nicotinamide adenine dinucleotide and regulation of nicotinamide adenine dinucleotide glycohydrolase activity in homogenates of rabbit skeletal muscle.", "content": "Protein binding of nicotinamide adenine dinucleotide and regulation of nicotinamide adenine dinucleotide glycohydrolase activity in homogenates of rabbit skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354231"}
{"pmid": "4354232", "title": "Activity of foot-and-mouth disease virus RNA-dependent RNA polymerase in vitro: inhibition by polyamines and poly(amino acid)s.", "content": "Activity of foot-and-mouth disease virus RNA-dependent RNA polymerase in vitro: inhibition by polyamines and poly(amino acid)s.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354232"}
{"pmid": "4354234", "title": "Bull semen nicotinamide adenine dinucleotide nucleosidase. VI. Fluorescence studies of the enzyme with reduced nicotinamide adenine dinucleotide.", "content": "Bull semen nicotinamide adenine dinucleotide nucleosidase. VI. Fluorescence studies of the enzyme with reduced nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354234"}
{"pmid": "4354233", "title": "Ligand-induced conformational states of rabbit liver fructose 1,6-bisphosphatase as revealed by digestion with subtilisin.", "content": "Ligand-induced conformational states of rabbit liver fructose 1,6-bisphosphatase as revealed by digestion with subtilisin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354233"}
{"pmid": "4354236", "title": "Relation between the time at which cytopathic endpoint occurs in infected cultures and the initial infective virus dose, with application to the study of inhibitors of cytopathic effect.", "content": "Relation between the time at which cytopathic endpoint occurs in infected cultures and the initial infective virus dose, with application to the study of inhibitors of cytopathic effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354236"}
{"pmid": "4354235", "title": "Carbohydrate composition of rat hepatocyte nuclear membrane as compared to normal, Morris hepatoma 7800, and phenobarbital-induced microsomal membranes.", "content": "Carbohydrate composition of rat hepatocyte nuclear membrane as compared to normal, Morris hepatoma 7800, and phenobarbital-induced microsomal membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354235"}
{"pmid": "4354237", "title": "Electron microscopy of porcine cytomegalovirus. Viral crystalline arrays and viral forms in the nasal mucosa of piglets.", "content": "Electron microscopy of porcine cytomegalovirus. Viral crystalline arrays and viral forms in the nasal mucosa of piglets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354237"}
{"pmid": "4354238", "title": "Enhancement of immunizing potency of a foot-and-mouth disease vaccine for cattle by treatment of the antigen with formaldehyde.", "content": "Enhancement of immunizing potency of a foot-and-mouth disease vaccine for cattle by treatment of the antigen with formaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354238"}
{"pmid": "4354239", "title": "Growth of rhinovirus type 14. Brief report.", "content": "Growth of rhinovirus type 14. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354239"}
{"pmid": "4354241", "title": "The significance of failure to isolate infectious viruses in cases of subacute sclerosing panencephalitis. Brief report.", "content": "The significance of failure to isolate infectious viruses in cases of subacute sclerosing panencephalitis. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354241"}
{"pmid": "4354240", "title": "A simple viability test of cells producing viral antigen. Brief report.", "content": "A simple viability test of cells producing viral antigen. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354240"}
{"pmid": "4354242", "title": "Physical adsorption of respiratory viruses to polystyrene tubes. Brief report.", "content": "Physical adsorption of respiratory viruses to polystyrene tubes. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354242"}
{"pmid": "4354244", "title": "Bile duct carcinoma in chronic ulcerative colitis.", "content": "Bile duct carcinoma in chronic ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354244"}
{"pmid": "4354245", "title": "Auto-antibodies in cirrhosis and hepatocellular carcinoma.", "content": "Auto-antibodies in cirrhosis and hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354245"}
{"pmid": "4354246", "title": "The chemical diagnosis of ganglioneuroma and neuroblastoma using random specimens of urine.", "content": "The chemical diagnosis of ganglioneuroma and neuroblastoma using random specimens of urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354246"}
{"pmid": "4354247", "title": "Lesch-Nyhan syndrome: absence of the mutant enzyme in erythrocytes of a heterozygote for both normal and mutant hypoxanthine-guanine phosphoribosyl transferase.", "content": "Lesch-Nyhan syndrome: absence of the mutant enzyme in erythrocytes of a heterozygote for both normal and mutant hypoxanthine-guanine phosphoribosyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354247"}
{"pmid": "4354248", "title": "Electrophoretic properties of hypoxanthine-guanine phosphoribosyl transferase in erythrocytes of subjects with Lesch-Nyhan syndrome.", "content": "Electrophoretic properties of hypoxanthine-guanine phosphoribosyl transferase in erythrocytes of subjects with Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354248"}
{"pmid": "4354249", "title": "Transmembrane potentials and phospholipid flip-flop in excitable membrane vesicles.", "content": "Transmembrane potentials and phospholipid flip-flop in excitable membrane vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354249"}
{"pmid": "4354250", "title": "Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis.", "content": "Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354250"}
{"pmid": "4354252", "title": "Specific cytoplasmic glucocorticoid hormone receptors in lactating mammary glands.", "content": "Specific cytoplasmic glucocorticoid hormone receptors in lactating mammary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354252"}
{"pmid": "4354251", "title": "Ascites tumor ribonucleic acid polymerases. Isolation, purification, and factor stimulation.", "content": "Ascites tumor ribonucleic acid polymerases. Isolation, purification, and factor stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354251"}
{"pmid": "4354253", "title": "Specific estrogen receptors in the lactating mammary gland of the rat.", "content": "Specific estrogen receptors in the lactating mammary gland of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354253"}
{"pmid": "4354256", "title": "Decline in glucose-6-phosphatase activity during prolonged postfixation washing.", "content": "Decline in glucose-6-phosphatase activity during prolonged postfixation washing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354256"}
{"pmid": "4354255", "title": "Purification of particulate glucose-6-phosphatase.", "content": "Purification of particulate glucose-6-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354255"}
{"pmid": "4354254", "title": "Cyclic adenosine 3',5'-monophosphate dependent phosphorylation of ribosomal proteins from bovine anterior pituitary gland.", "content": "Cyclic adenosine 3',5'-monophosphate dependent phosphorylation of ribosomal proteins from bovine anterior pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354254"}
{"pmid": "4354257", "title": "A survey of the different methods used. Experimental study on the application of some methods found suitable to our country.", "content": "A survey of the different methods used. Experimental study on the application of some methods found suitable to our country.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354257"}
{"pmid": "4354259", "title": "Evidence for an angiotensinogen-stimulating factor after nephrectomy.", "content": "Evidence for an angiotensinogen-stimulating factor after nephrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354259"}
{"pmid": "4354258", "title": "Inhibition and enhancement of the noradrenaline constrictor response by methylxanthines.", "content": "Inhibition and enhancement of the noradrenaline constrictor response by methylxanthines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354258"}
{"pmid": "4354260", "title": "Nonspecific entry of thoracic duct immunoblasts into intradermal foci of antigens.", "content": "Nonspecific entry of thoracic duct immunoblasts into intradermal foci of antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354260"}
{"pmid": "4354261", "title": "Nuclear differentiation and nucleic acid synthesis in well-fed exconjugants of Paramecium aurelia.", "content": "Nuclear differentiation and nucleic acid synthesis in well-fed exconjugants of Paramecium aurelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354261"}
{"pmid": "4354285", "title": "Carcinogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine with various kinds of surfactant in the glandular stomach of rats.", "content": "Carcinogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine with various kinds of surfactant in the glandular stomach of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354285"}
{"pmid": "4354286", "title": "Effect of adenosine3', 5'-monophosphate on thymidine kinase in tumor cells.", "content": "Effect of adenosine3', 5'-monophosphate on thymidine kinase in tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354286"}
{"pmid": "4354287", "title": "Heterogeneity of ferritin from 3'-methyl-4-(dimethylamino) azobenzene-induced hepatomas.", "content": "Heterogeneity of ferritin from 3'-methyl-4-(dimethylamino) azobenzene-induced hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354287"}
{"pmid": "4354288", "title": "Mucopolysaccharides of rat ascites hepatoma cells.", "content": "Mucopolysaccharides of rat ascites hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354288"}
{"pmid": "4354289", "title": "Production of growth-and differentiation-stimulating factors for mouse leukemia cells by different cell species.", "content": "Production of growth-and differentiation-stimulating factors for mouse leukemia cells by different cell species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354289"}
{"pmid": "4354290", "title": "Immuno-electron microscopic studies on cell surface antigens of Friend virus-induced tumor in the rat.", "content": "Immuno-electron microscopic studies on cell surface antigens of Friend virus-induced tumor in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354290"}
{"pmid": "4354292", "title": "Multinucleated giant cell formation in cultured cells by murine leukemia virus infection.", "content": "Multinucleated giant cell formation in cultured cells by murine leukemia virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354292"}
{"pmid": "4354291", "title": "Chromosomal aberrations of a lymphoblastoid cell line by experimental infection with Epstein-Barr virus.", "content": "Chromosomal aberrations of a lymphoblastoid cell line by experimental infection with Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354291"}
{"pmid": "4354294", "title": "Human plasma iron responses following test doses of iron from known sources.", "content": "Human plasma iron responses following test doses of iron from known sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354294"}
{"pmid": "4354298", "title": "Reconstruction of the primary sequence of a protein from peptides of known sequence.", "content": "Reconstruction of the primary sequence of a protein from peptides of known sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354298"}
{"pmid": "4354309", "title": "Smooth muscle-like cells in ovaries of the hamster and gerbil.", "content": "Smooth muscle-like cells in ovaries of the hamster and gerbil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354309"}
{"pmid": "4354297", "title": "Comparison of glucose-6-phosphatase activity in unfertilized and fertilized sea urchin egg fractions.", "content": "Comparison of glucose-6-phosphatase activity in unfertilized and fertilized sea urchin egg fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354297"}
{"pmid": "4354310", "title": "Fluorescence and electron microscopy of the monoamine-containing cells in the turtle heart.", "content": "Fluorescence and electron microscopy of the monoamine-containing cells in the turtle heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354310"}
{"pmid": "4354312", "title": "Mediastinoscopic observations of metastatic spread in pulmonary carcinoma.", "content": "Mediastinoscopic observations of metastatic spread in pulmonary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354312"}
{"pmid": "4354311", "title": "A quantitative electron microscopic analysis of myelination in the optic nerve of suckling rats treated with an inhibitor of cholesterol biosynthesis.", "content": "A quantitative electron microscopic analysis of myelination in the optic nerve of suckling rats treated with an inhibitor of cholesterol biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354311"}
{"pmid": "4354313", "title": "Mechanism of enzyme action.", "content": "Mechanism of enzyme action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354313"}
{"pmid": "4354314", "title": "Toward molecular mechanisms of developmental processes.", "content": "Toward molecular mechanisms of developmental processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354314"}
{"pmid": "4354315", "title": "The cell surface membrane: biochemical aspects and biophysical probes.", "content": "The cell surface membrane: biochemical aspects and biophysical probes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354315"}
{"pmid": "4354316", "title": "Stimulation of polypeptide synthesis by cyclic 3'-5'-guanosine monophosphate.", "content": "Stimulation of polypeptide synthesis by cyclic 3'-5'-guanosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354316"}
{"pmid": "4354317", "title": "Studies on calciferol metabolism. VII. The effects of actinomycin D and cycloheximide on the metabolism, tissue and subcellular localization, and action of vitamin D3.", "content": "Studies on calciferol metabolism. VII. The effects of actinomycin D and cycloheximide on the metabolism, tissue and subcellular localization, and action of vitamin D3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354317"}
{"pmid": "4354318", "title": "Effects of 2,4-substituents of deuteroheme upon peroxidase functions. II. Reactions of peroxidases and metmyoglobin with azide, cyanide and fluoride.", "content": "Effects of 2,4-substituents of deuteroheme upon peroxidase functions. II. Reactions of peroxidases and metmyoglobin with azide, cyanide and fluoride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354318"}
{"pmid": "4354319", "title": "The b cytochromes in succinate--cytochrome c reductase from pigeon breast mitochondria.", "content": "The b cytochromes in succinate--cytochrome c reductase from pigeon breast mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354319"}
{"pmid": "4354321", "title": "Receptors for glucocorticoids in lung tissue.", "content": "Receptors for glucocorticoids in lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354321"}
{"pmid": "4354320", "title": "Bull semen nicotinamide adenine dinucleotide nucleosidase. VII. Nonenzymatic basis of apparent transglycosidation with histamine.", "content": "Bull semen nicotinamide adenine dinucleotide nucleosidase. VII. Nonenzymatic basis of apparent transglycosidation with histamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354320"}
{"pmid": "4354322", "title": "Cytochrome c interaction with membranes. II. Comparative study of the interaction of c cytochromes with the mitochondrial membrane.", "content": "Cytochrome c interaction with membranes. II. Comparative study of the interaction of c cytochromes with the mitochondrial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354322"}
{"pmid": "4354323", "title": "The effects of actin on the electron spin resonance of spin-labeled myosin.", "content": "The effects of actin on the electron spin resonance of spin-labeled myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354323"}
{"pmid": "4354325", "title": "The activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase and fructose diphosphatase in muscles from vertebrates and invertebrates.", "content": "The activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase and fructose diphosphatase in muscles from vertebrates and invertebrates. 1. The activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase and fructose diphosphatase in crude homogenates of vertebrate and invertebrate muscles are reported. 2. Pyruvate carboxylase activity was present in all insect flight muscles that were investigated: in homogenates of bumble-bee flight muscle the activity was inhibited by ADP and activated by acetyl-CoA, and it was distributed mainly in the mitochondrial fraction. This is the first demonstration of pyruvate carboxylase activity in muscle. However, the activity appears to be restricted to insect flight muscle, since it was not found in other invertebrate or vertebrate muscles. 3. Since the three enzymes were never found together in the same muscle, it is concluded that these enzymes cannot provide a pathway for the synthesis of glycogen from lactate or pyruvate in muscle. Other roles for these enzymes in muscle are suggested. In particular, pyruvate carboxylase may be present in insect flight muscle for the provision of oxaloacetate to support the large increase in activity of the tricarboxylic acid cycle which occurs when an insect takes flight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354325"}
{"pmid": "4354327", "title": "Atropine sulphate absorption from an intramuscular injection of a mixture of the oxime, P2S, and atropine in exercising humans.", "content": "Atropine sulphate absorption from an intramuscular injection of a mixture of the oxime, P2S, and atropine in exercising humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354327"}
{"pmid": "4354326", "title": "Effects of Naja nivea venom on nerve, cardiac and skeletal muscle activity of the frog.", "content": "Effects of Naja nivea venom on nerve, cardiac and skeletal muscle activity of the frog. 1. The effects of 1 mg/ml whole Naja nivea (Cape cobra) venom, and of three different toxins isolated from it, on spinal reflex excitability and cardiac and skeletal muscle activity of the frog (Xenopus laevis), were studied. Isolated spinal cords, sciatic nerve-gastrocnemius muscle units and isolated heart preparations were used.2. Synaptic efficiency and/or motoneurone excitability ceased totally and irreversibly after the application of whole venom within 18.5 minutes. The application of alpha toxin caused polysynaptic reactivation of the motoneurones after the monosynaptic response elicited by electrical stimulation, i.e. it had an excitatory effect, which was retained after washing off the toxin. The effect of beta toxin resembled that of alpha toxin, except that the effect was lost after the toxin was washed off. The delta toxin abolished all nervous reactivity irreversibly and was found to be 2.64 times more effective in this respect than whole venom.3. Responses of the gastrocnemius muscle to electrical stimulation of its motor nerve ceased 10 to 20 min after application of the venom. The muscle usually still responded slightly to direct stimulation for a few minutes. The effect was irreversible. The venom did not only block neuromuscular transmission, but also affected the muscle fibre itself. Nerve conductivity was relatively resistant to the venom; alpha and beta toxins produced similar results but were less effective.4. The application of whole venom (1 mg/ml) to the isolated heart resulted in complete spasm of the ventricle within 3 to 8 minutes. The atria continued contracting long after the ventricle ceased. When the venom was washed off, contractions of the atria were restored, while the ventricle remained irreversibly in a state of spasm. The alpha, beta and delta toxins weakened the contractions of the ventricle, but did not produce spasm. The effect on the ventricle was reversible. Contractions of the atria remained apparently unaltered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354326"}
{"pmid": "4354328", "title": "Specificity of adenosine on transmitter output at the neuromuscular junction.", "content": "Specificity of adenosine on transmitter output at the neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354328"}
{"pmid": "4354329", "title": "Analysis of labile brain constituents using a technique for the instantaneous fixation of brain tissue in vivo.", "content": "Analysis of labile brain constituents using a technique for the instantaneous fixation of brain tissue in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354329"}
{"pmid": "4354330", "title": "Chronic dorsal root section on free amino acid levels in the rabbit spinal cord.", "content": "Chronic dorsal root section on free amino acid levels in the rabbit spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354330"}
{"pmid": "4354334", "title": "Fixation of a Salmonella minnesota R-form glycolipid on the membrane of normal and transformed rat-embryo fibroblasts.", "content": "Fixation of a Salmonella minnesota R-form glycolipid on the membrane of normal and transformed rat-embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354334"}
{"pmid": "4354333", "title": "Evidence for a catalytic-centre heterogeneity of molybdoferredoxin from Clostridium pasteurianum.", "content": "Evidence for a catalytic-centre heterogeneity of molybdoferredoxin from Clostridium pasteurianum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354333"}
{"pmid": "4354336", "title": "The effect of insulin and growth hormone on the flux of tracer from labelled lactate in perfused rat heart.", "content": "The effect of insulin and growth hormone on the flux of tracer from labelled lactate in perfused rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354336"}
{"pmid": "4354335", "title": "The flux of pyruvate in perfused rat heart.", "content": "The flux of pyruvate in perfused rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354335"}
{"pmid": "4354338", "title": "Relationships between intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.", "content": "Relationships between intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354338"}
{"pmid": "4354337", "title": "Adenylate-cyclase receptors for adrenergic neurotransmitters in rat cerebral cortex.", "content": "Adenylate-cyclase receptors for adrenergic neurotransmitters in rat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354337"}
{"pmid": "4354339", "title": "The neutral proteases of human granulocytes. Isolation and partial characterization of two granulocyte collagenases.", "content": "The neutral proteases of human granulocytes. Isolation and partial characterization of two granulocyte collagenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354339"}
{"pmid": "4354331", "title": "An antibody survey of children in an Ottawa public school.", "content": "An antibody survey of children in an Ottawa public school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354331"}
{"pmid": "4354340", "title": "Formation of the yeast mitochondrial membrane. 1. Effects of inhibitors of protein synthesis on the kinetics of enzyme appearance during glucose derepression.", "content": "Formation of the yeast mitochondrial membrane. 1. Effects of inhibitors of protein synthesis on the kinetics of enzyme appearance during glucose derepression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354340"}
{"pmid": "4354342", "title": "Magnetic-resonance studies of the interactions between bovine-serum albumin and surfactants. 1. Nature of binding site.", "content": "Magnetic-resonance studies of the interactions between bovine-serum albumin and surfactants. 1. Nature of binding site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354342"}
{"pmid": "4354343", "title": "Magnetic-resonance studies of the interactions between bovine-serum albumin and surfactants. 2. Effect of surfactants on the structure of bovine-serum albumin.", "content": "Magnetic-resonance studies of the interactions between bovine-serum albumin and surfactants. 2. Effect of surfactants on the structure of bovine-serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354343"}
{"pmid": "4354341", "title": "ATP-controlled fatty-acid synthesis in cultured arterial fibroblasts.", "content": "ATP-controlled fatty-acid synthesis in cultured arterial fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354341"}
{"pmid": "4354344", "title": "Tyrosine substitutions resulting from suppression of amber mutants of iso-1-cytochrome c in yeast.", "content": "Tyrosine substitutions resulting from suppression of amber mutants of iso-1-cytochrome c in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354344"}
{"pmid": "4354345", "title": "Confirmation of UAG as a nonsense codon in bakers' yeast by amino acid replacements of glutamic acid 71 in iso-1-cytochrome c.", "content": "Confirmation of UAG as a nonsense codon in bakers' yeast by amino acid replacements of glutamic acid 71 in iso-1-cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354345"}
{"pmid": "4354346", "title": "DNA synthesis in polyoma virus infection. II. Relationship between viral DNA replication and initiation of cellular DNA replicons.", "content": "DNA synthesis in polyoma virus infection. II. Relationship between viral DNA replication and initiation of cellular DNA replicons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354346"}
{"pmid": "4354347", "title": "Evolution of transfer RNA.", "content": "Evolution of transfer RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354347"}
{"pmid": "4354350", "title": "An in vitro assay for corticotropin releasing factor(s) using suspensions of isolated pituitary cells.", "content": "An in vitro assay for corticotropin releasing factor(s) using suspensions of isolated pituitary cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354350"}
{"pmid": "4354355", "title": "Autoimmune thrombocytopenia occurring in a young woman with idiopathic haemochromatosis.", "content": "Autoimmune thrombocytopenia occurring in a young woman with idiopathic haemochromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354355"}
{"pmid": "4354365", "title": "Interaction of glucocorticoids with rat liver nuclei. I. Role of the cytosol proteins.", "content": "Interaction of glucocorticoids with rat liver nuclei. I. Role of the cytosol proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354365"}
{"pmid": "4354366", "title": "Interaction of glucocorticoids with rat liver nuclei. II. Studies on the nature of the cytosol transfer factor and the nuclear acceptor site.", "content": "Interaction of glucocorticoids with rat liver nuclei. II. Studies on the nature of the cytosol transfer factor and the nuclear acceptor site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354366"}
{"pmid": "4354367", "title": "Purification of (14C) protocollagen and its hydroxylation by prolyl-hydroxylase.", "content": "Purification of (14C) protocollagen and its hydroxylation by prolyl-hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354367"}
{"pmid": "4354368", "title": "Synthesis of four undecanucleotides complementary to a region of the coat protein cistron of phage fd.", "content": "Synthesis of four undecanucleotides complementary to a region of the coat protein cistron of phage fd.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354368"}
{"pmid": "4354369", "title": "Circular dichroism of liver alcohol dehydrogenase complexes with auramine O.", "content": "Circular dichroism of liver alcohol dehydrogenase complexes with auramine O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354369"}
{"pmid": "4354370", "title": "Effect on coenzyme on the bis(8-anilino-1-naphthalenesulfonate)-linked association of beef muscle lactic dehydrogenase.", "content": "Effect on coenzyme on the bis(8-anilino-1-naphthalenesulfonate)-linked association of beef muscle lactic dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354370"}
{"pmid": "4354371", "title": "Lanthanide ions activate alpha-amylase.", "content": "Lanthanide ions activate alpha-amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354371"}
{"pmid": "4354372", "title": "Cooperativity in human erythrocyte phosphofructokinase.", "content": "Cooperativity in human erythrocyte phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354372"}
{"pmid": "4354374", "title": "Spectrophotometric assay of 2',3'-cyclic nucleotide 3'-phosphohydrolase: application to the enzyme in bovine brain.", "content": "Spectrophotometric assay of 2',3'-cyclic nucleotide 3'-phosphohydrolase: application to the enzyme in bovine brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354374"}
{"pmid": "4354373", "title": "Elevated levels of acceptor activity of hepatoma transfer ribonucleic acid.", "content": "Elevated levels of acceptor activity of hepatoma transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354373"}
{"pmid": "4354375", "title": "Excitatory effects of 5-hydroxytryptamine in the hippocampal-septal circuit.", "content": "Excitatory effects of 5-hydroxytryptamine in the hippocampal-septal circuit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354375"}
{"pmid": "4354376", "title": "Increased shock sensitivity in rats with experimental allergic encephalomyelitis and reversal by 5-hydroxytryptophan.", "content": "Increased shock sensitivity in rats with experimental allergic encephalomyelitis and reversal by 5-hydroxytryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354376"}
{"pmid": "4354377", "title": "Bicuculline and picrotoxin sensitive inhibition in interpositus neurones of cat.", "content": "Bicuculline and picrotoxin sensitive inhibition in interpositus neurones of cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354377"}
{"pmid": "4354378", "title": "A simple preparation of bicuculline methiodide, a water-soluble GABA antagonist.", "content": "A simple preparation of bicuculline methiodide, a water-soluble GABA antagonist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354378"}
{"pmid": "4354380", "title": "Short-term changes in the firing pattern of hypothalamic neurons during Pavlovian conditioning.", "content": "Short-term changes in the firing pattern of hypothalamic neurons during Pavlovian conditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354380"}
{"pmid": "4354379", "title": "Subarachnoid versus ventricular perfusion in the rabbit.", "content": "Subarachnoid versus ventricular perfusion in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354379"}
{"pmid": "4354381", "title": "Hypothermia--a practical aid in veterinary surgery.", "content": "Hypothermia--a practical aid in veterinary surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354381"}
{"pmid": "4354383", "title": "Synthesis and evaluation of the anticancer activity of a new series of methanesulfonates.", "content": "Synthesis and evaluation of the anticancer activity of a new series of methanesulfonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354383"}
{"pmid": "4354384", "title": "Focal rhythmic EEG slowing with temporal lobe tumors. Report of six cases.", "content": "Focal rhythmic EEG slowing with temporal lobe tumors. Report of six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354384"}
{"pmid": "4354385", "title": "The influence of topically applied D-tubocurarine on the taste-induced electrical nerve activity in the frog.", "content": "The influence of topically applied D-tubocurarine on the taste-induced electrical nerve activity in the frog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354385"}
{"pmid": "4354389", "title": "The role of transcortin in the distribution of corticosterone in the rat.", "content": "The role of transcortin in the distribution of corticosterone in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354389"}
{"pmid": "4354390", "title": "Plasma calcitonin-like activity and urinary cyclic adenosine monophosphate during pregnancy, parturition, and lactation in cows with parturient hypocalcemia.", "content": "Plasma calcitonin-like activity and urinary cyclic adenosine monophosphate during pregnancy, parturition, and lactation in cows with parturient hypocalcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354390"}
{"pmid": "4354388", "title": "Lipolytic activity of rat pituitaries in vitro.", "content": "Lipolytic activity of rat pituitaries in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354388"}
{"pmid": "4354391", "title": "Influence of median eminence extracts on neosynthesis and release of ACTH.", "content": "Influence of median eminence extracts on neosynthesis and release of ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354391"}
{"pmid": "4354392", "title": "Biological ACTH activity of lipid mobilizing peptide fractions from hog pituitaries.", "content": "Biological ACTH activity of lipid mobilizing peptide fractions from hog pituitaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354392"}
{"pmid": "4354393", "title": "Fatty changes and hepatic cell excretion in avian liver. An electron microscopical study of Kepone toxicity.", "content": "Fatty changes and hepatic cell excretion in avian liver. An electron microscopical study of Kepone toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354393"}
{"pmid": "4354394", "title": "Experimental infections with Pasteurella septica (sero-group A) and an adeno-or enterovirus in gnotobiotic piglets.", "content": "Experimental infections with Pasteurella septica (sero-group A) and an adeno-or enterovirus in gnotobiotic piglets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354394"}
{"pmid": "4354395", "title": "Lipid characterization of bovine serum lipoproteins throughout gestation and lactation.", "content": "Lipid characterization of bovine serum lipoproteins throughout gestation and lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354395"}
{"pmid": "4354396", "title": "Inhibition of urea on the hepatocarcinogensis induced by N, N-dimethyl-4-aminoazobenzene in rats.", "content": "Inhibition of urea on the hepatocarcinogensis induced by N, N-dimethyl-4-aminoazobenzene in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354396"}
{"pmid": "4354398", "title": "Modulation of postural reflexes by voluntary movement. II. Modulation at an inactive joint.", "content": "Modulation of postural reflexes by voluntary movement. II. Modulation at an inactive joint. We have observed that there is a brief, 400 msec period of widespread facilitation of both the Hoffmann and the tendon-jerk reflexes associated with the initiation of a variety of local, voluntary, isometric efforts. It is suggested that the site of this facilitation lies within the spinal cord. We have also observed that this period is followed, for the Hoffmann reflex, by a period of spinal inhibition. By contrast, the tendon-jerk is facilitated, at a reduced level, for at least another 500 msec by mechanisms probably working at the muscle spindle. These results are discussed in comparison with experiments involving activation of the reflex agonist and antagonist muscles. It is proposed that voluntary control of the locomotor system is organized through separate mechanisms for muscle recruitment and for regulation of the sensitivity of the myotatic reflex loop.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354398"}
{"pmid": "4354397", "title": "Multiple cerebral gliomas in multiple sclerosis.", "content": "Multiple cerebral gliomas in multiple sclerosis. A patient with multiple sclerosis and a multicentric anaplastic astrocytoma is described. The evidence suggests that the relationship is not coincidental and that the astrocytomas originate in multiple sclerosis plaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354397"}
{"pmid": "4354399", "title": "Comparison of the tonic stretch reflex in athetotic patients during rest and voluntary activity.", "content": "Comparison of the tonic stretch reflex in athetotic patients during rest and voluntary activity. An electromyographic technique was used to record the tonic stretch reflex (TSR) responses to passive sinusoidal stretching of biceps brachii muscle in athetotic patients. The TSR transmission characteristics measured while the patient was in a relaxed state were compared with those measured while the patient was voluntarily active. The resting TSR and action TSR were found to differ markedly. Sensitivity, pattern, duration, and timing of the TSR responses were all changed during voluntary activity. The results suggest that the TSR in athetosis is functionally reorganized by supraspinal influences during voluntary activity. It is proposed that athetoid movements and action tremor may be a manifestation of abnormal action TSR caused by faulty supra-spinal control during activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354399"}
{"pmid": "4354400", "title": "Significance of plasma lysolecithin in patients with multiple sclerosis: a longitudinal study.", "content": "Significance of plasma lysolecithin in patients with multiple sclerosis: a longitudinal study. Five patients with multiple sclerosis and four normal subjects have been followed for over two years. Plasma phospholipid levels and phospholipid fatty acid composition have been assayed periodically. The increased amount of plasma lysolecithin already described by us has been confirmed in this longitudinal study. A significant increase in saturated fatty acids of lysolecithin has also been demonstrated. In contrast, the lecithin concentration and fatty acid composition do not show any significant variations. The lysolecithin saturated/unsaturated fatty acid ratio was different in the same patients at different times, but no correlation was established between these variations and the clinical symptoms measured using the Kurtzke scale. The possible significance of saturated fatty acid increase in lysolecithin in the pathogenetic mechanisms of multiple sclerosis is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354400"}
{"pmid": "4354401", "title": "Renshaw cell activity in man.", "content": "Renshaw cell activity in man. The H-reflex elicited in triceps surae by percutaneous stimulation of the posterior tibial nerve was conditioned by stimuli applied through the same electrode. The differential sensitivity of motor and sensory fibres to duration of the stimulus pulse made it possible to condition the H-reflex with either a motor or a sensory stimulus. With both types of conditioning, the H-reflex was inhibited at conditioning-test intervals of 2-3 msec and was then facilitated, the peak of facilitation occurring at 5-8 msec with motor conditioning and 6-10 msec with sensory conditioning. The phase of facilitation was followed by further inhibition. We have concluded (1) that the effects of motor conditioning on the H-reflex result from the discharge of Renshaw cells activated by the antidromic volley in the motor axons, and (2) that the effects of sensory conditioning (at the times used in these experiments) are largely due to the activation of Renshaw cells secondary to the discharge of alpha motoneurones by the conditioning volley.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354401"}
{"pmid": "4354402", "title": "Some effects of chloramphenicol and ethidium bromide on Tetrahymena pyriformis.", "content": "Some effects of chloramphenicol and ethidium bromide on Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354402"}
{"pmid": "4354403", "title": "The enzymic synthesis of dihydropteroate and dihydrofolate by Plasmodium berghei.", "content": "The enzymic synthesis of dihydropteroate and dihydrofolate by Plasmodium berghei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354403"}
{"pmid": "4354404", "title": "Two improved methods for the determination of soluble carbohydrates.", "content": "Two improved methods for the determination of soluble carbohydrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354404"}
{"pmid": "4354405", "title": "An operon for histidine biosynthesis in Streptomyces coelicolor. II. Biochemical evidence.", "content": "An operon for histidine biosynthesis in Streptomyces coelicolor. II. Biochemical evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354405"}
{"pmid": "4354406", "title": "Cure of the child with cancer.", "content": "Cure of the child with cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354406"}
{"pmid": "4354408", "title": "Clostridial brain abscess and hyperbaric oxygen.", "content": "Clostridial brain abscess and hyperbaric oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354408"}
{"pmid": "4354407", "title": "Bell's palsy and its treatment.", "content": "Bell's palsy and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354407"}
{"pmid": "4354409", "title": "Biogenic monoamines in the cyclostome and lower vertebrate brain.", "content": "Biogenic monoamines in the cyclostome and lower vertebrate brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354409"}
{"pmid": "4354413", "title": "Paraneoplastic syndromes. A clinically relevant concept in cancer.", "content": "Paraneoplastic syndromes. A clinically relevant concept in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354413"}
{"pmid": "4354420", "title": "Mechanism of the short-term poststimulatory depression of the cochlear microphonics (hysteresis).", "content": "Mechanism of the short-term poststimulatory depression of the cochlear microphonics (hysteresis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354420"}
{"pmid": "4354410", "title": "Understanding biochemical pathology of depressive illness. An overview.", "content": "Understanding biochemical pathology of depressive illness. An overview.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354410"}
{"pmid": "4354425", "title": "Faith healing-Pennsylvania style.", "content": "Faith healing-Pennsylvania style.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354425"}
{"pmid": "4354426", "title": "Granulomatous disease of the lungs.", "content": "Granulomatous disease of the lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354426"}
{"pmid": "4354427", "title": "The radiology of bacterial and viral pneumonias.", "content": "The radiology of bacterial and viral pneumonias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354427"}
{"pmid": "4354428", "title": "The radiographic presentation of pulmonary opportunistic inflammatory disease.", "content": "The radiographic presentation of pulmonary opportunistic inflammatory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354428"}
{"pmid": "4354429", "title": "Bronchographic criteria of inflammatory disease and radiologic lung biopsy techniques.", "content": "Bronchographic criteria of inflammatory disease and radiologic lung biopsy techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354429"}
{"pmid": "4354430", "title": "Homeostasis and the prostaglandins.", "content": "Homeostasis and the prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354430"}
{"pmid": "4354437", "title": "Proline hydroxylase in injury-induced arteriosclerosis.", "content": "Proline hydroxylase in injury-induced arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354437"}
{"pmid": "4354438", "title": "Polyol pathway activity in aorta.", "content": "Polyol pathway activity in aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354438"}
{"pmid": "4354439", "title": "Clinical amoebiasis syndrome and case reports of a few unusual cases of amoebiasis.", "content": "Clinical amoebiasis syndrome and case reports of a few unusual cases of amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354439"}
{"pmid": "4354442", "title": "Netherlands Society for Microbiology meeting at Delft on 25 October 1972. Homologies in the amino acid sequences of cytochrome c-555 from the green photosynthetic bacteria \"Chloropseudomonas ethylica\" and Chlorobium thiosulfatophilium.", "content": "Netherlands Society for Microbiology meeting at Delft on 25 October 1972. Homologies in the amino acid sequences of cytochrome c-555 from the green photosynthetic bacteria \"Chloropseudomonas ethylica\" and Chlorobium thiosulfatophilium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354442"}
{"pmid": "4354440", "title": "The identification and semi-quantitative assay of some fat-soluble vitamins and antioxidants in pharmaceutical products and animal feeds by thin-layer chromatography.", "content": "The identification and semi-quantitative assay of some fat-soluble vitamins and antioxidants in pharmaceutical products and animal feeds by thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354440"}
{"pmid": "4354441", "title": "Hormones and gene expression.", "content": "Hormones and gene expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354441"}
{"pmid": "4354443", "title": "Effects of ACTH, adrenalectomy and time of day on emotional activity of the rat.", "content": "Effects of ACTH, adrenalectomy and time of day on emotional activity of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354443"}
{"pmid": "4354444", "title": "Lymphocyte activation: the dualistic effect of cAMP.", "content": "Lymphocyte activation: the dualistic effect of cAMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354444"}
{"pmid": "4354445", "title": "Cyclic 3',5'-AMP phosphodiesterase of Neurospora crassa.", "content": "Cyclic 3',5'-AMP phosphodiesterase of Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354445"}
{"pmid": "4354446", "title": "A novel monosialoganglioside synthesized by a rat brain cytidine-5'-monophospho-N-acetylneuraminic acid: galactosyl-N-acetylgalactosaminyl-galactosyl-glucosylceramide sialyltransferase.", "content": "A novel monosialoganglioside synthesized by a rat brain cytidine-5'-monophospho-N-acetylneuraminic acid: galactosyl-N-acetylgalactosaminyl-galactosyl-glucosylceramide sialyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354446"}
{"pmid": "4354447", "title": "Quiescent SV40 virus transformed 3T3 cells in culture.", "content": "Quiescent SV40 virus transformed 3T3 cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354447"}
{"pmid": "4354448", "title": "The activation of adenylate cyclase. II. The postulated presence of (A) adenylate cyclase in a phospho (inhibited) form (B) a dephospho (activated) form with a cyclic adenylate stimulated membrane protein kinase.", "content": "The activation of adenylate cyclase. II. The postulated presence of (A) adenylate cyclase in a phospho (inhibited) form (B) a dephospho (activated) form with a cyclic adenylate stimulated membrane protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354448"}
{"pmid": "4354449", "title": "The occurrence of fluoride stimulated membrane phosphoprotein phosphatase.", "content": "The occurrence of fluoride stimulated membrane phosphoprotein phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354449"}
{"pmid": "4354450", "title": "Synthesis of the E. coli pyruvate dehydrogenase complex: non-dependence on 3'-5'-cyclic AMP.", "content": "Synthesis of the E. coli pyruvate dehydrogenase complex: non-dependence on 3'-5'-cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354450"}
{"pmid": "4354451", "title": "Evidence for RNA-linked nascent strands in polyoma virus DNA replication.", "content": "Evidence for RNA-linked nascent strands in polyoma virus DNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354451"}
{"pmid": "4354452", "title": "Decreased binding of insulin to its receptors in rats with hormone induced insulin resistance.", "content": "Decreased binding of insulin to its receptors in rats with hormone induced insulin resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354452"}
{"pmid": "4354453", "title": "A 5'-amino analog of adenosine diphosphate.", "content": "A 5'-amino analog of adenosine diphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354453"}
{"pmid": "4354454", "title": "Studies on the in vitro effects of insulin on glycogen synthesis and ultrastructure in isolated rat liver hepatocytes.", "content": "Studies on the in vitro effects of insulin on glycogen synthesis and ultrastructure in isolated rat liver hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354454"}
{"pmid": "4354455", "title": "The messenger-directed synthesis of the alpha-fragment of the enzyme beta-galactosidase.", "content": "The messenger-directed synthesis of the alpha-fragment of the enzyme beta-galactosidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354455"}
{"pmid": "4354456", "title": "Changes of the activities of adenyl cyclase and cAMP-phosphodiesterase and of the level of 3'5' cyclic adenosine monophosphate in rat mammary gland during pregnancy and lactation.", "content": "Changes of the activities of adenyl cyclase and cAMP-phosphodiesterase and of the level of 3'5' cyclic adenosine monophosphate in rat mammary gland during pregnancy and lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354456"}
{"pmid": "4354457", "title": "Kinetic and molecular characteristics of allosteric pyruvate kinase from muscle tissue of the sea mussel Mytilus edulis L.", "content": "Kinetic and molecular characteristics of allosteric pyruvate kinase from muscle tissue of the sea mussel Mytilus edulis L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354457"}
{"pmid": "4354458", "title": "Glucose-6-phosphatase activity in a soluble fraction from cotyledon tissue of Brassica nigra.", "content": "Glucose-6-phosphatase activity in a soluble fraction from cotyledon tissue of Brassica nigra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354458"}
{"pmid": "4354459", "title": "Effects of sulfhydryl reagents on synthetic and hydrolytic activities of multifunctional glucose-6-phosphatase.", "content": "Effects of sulfhydryl reagents on synthetic and hydrolytic activities of multifunctional glucose-6-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354459"}
{"pmid": "4354460", "title": "Properties of adenylate cyclase in mucosal cells of the rabbit ileum and the effect of cholera toxin.", "content": "Properties of adenylate cyclase in mucosal cells of the rabbit ileum and the effect of cholera toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354460"}
{"pmid": "4354461", "title": "Collagenase activity in homogenates of the involuting rat uterus.", "content": "Collagenase activity in homogenates of the involuting rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354461"}
{"pmid": "4354462", "title": "Effect of spermine on the reaction catalyzed by threonyl-tRNA synthetase from rat liver.", "content": "Effect of spermine on the reaction catalyzed by threonyl-tRNA synthetase from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354462"}
{"pmid": "4354463", "title": "Comparative morphometric study of the human pancreas in its normal state and in primary chronic calcifying pancreatitis.", "content": "Comparative morphometric study of the human pancreas in its normal state and in primary chronic calcifying pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354463"}
{"pmid": "4354465", "title": "Effect of pyrazole on ACTH stimulated lipolysis \"in vivo\".", "content": "Effect of pyrazole on ACTH stimulated lipolysis \"in vivo\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354465"}
{"pmid": "4354464", "title": "Prostaglandin E1 and platelets.", "content": "Prostaglandin E1 and platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354464"}
{"pmid": "4354466", "title": "Study of steatosis induced in the rat by orotic acid.", "content": "Study of steatosis induced in the rat by orotic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354466"}
{"pmid": "4354467", "title": "Prognosis of early bronchogenic carcinoma. Survival curves of 451 patients after resection of lung cancer in relation to the results of pre-operative tuberculin skin test.", "content": "Prognosis of early bronchogenic carcinoma. Survival curves of 451 patients after resection of lung cancer in relation to the results of pre-operative tuberculin skin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354467"}
{"pmid": "4354468", "title": "Direct stimulant effect of cyclic AMP and dibutyryl cAMP on glycogenolysis by hepatocytes in histiotypic culture.", "content": "Direct stimulant effect of cyclic AMP and dibutyryl cAMP on glycogenolysis by hepatocytes in histiotypic culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354468"}
{"pmid": "4354469", "title": "Activation of endogenous C-type oncornavirus by 5-bromodeoxyuridine in cultured embryonic rat fibroblasts.", "content": "Activation of endogenous C-type oncornavirus by 5-bromodeoxyuridine in cultured embryonic rat fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354469"}
{"pmid": "4354473", "title": "Immunological responses of rabbits artificially infested with the cattle grubs Hypoderma bovis (L.) and H. Lineatum (De Vill.) (Diptera: Oestridae).", "content": "Immunological responses of rabbits artificially infested with the cattle grubs Hypoderma bovis (L.) and H. Lineatum (De Vill.) (Diptera: Oestridae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354473"}
{"pmid": "4354474", "title": "Experimental genital herpes infection of the marmoset.", "content": "Experimental genital herpes infection of the marmoset.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354474"}
{"pmid": "4354475", "title": "Production of non-defective and defective oligomers of viral DNA in mouse 3T3 cells transformed by a thermosensitive mutant of polyoma virus.", "content": "Production of non-defective and defective oligomers of viral DNA in mouse 3T3 cells transformed by a thermosensitive mutant of polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354475"}
{"pmid": "4354476", "title": "Nuclear magnetic resonance study of exchangeable protons in ferrocytochrome c.", "content": "Nuclear magnetic resonance study of exchangeable protons in ferrocytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354476"}
{"pmid": "4354477", "title": "Defective interfering particles of poliovirus. II. Nature of the defect.", "content": "Defective interfering particles of poliovirus. II. Nature of the defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354477"}
{"pmid": "4354478", "title": "Defective interfering particles of poliovirus. 3. Interference and enrichment.", "content": "Defective interfering particles of poliovirus. 3. Interference and enrichment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354478"}
{"pmid": "4354480", "title": "Localization of free radicals on irradiated deoxyribonucleohistone.", "content": "Localization of free radicals on irradiated deoxyribonucleohistone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354480"}
{"pmid": "4354481", "title": "Renal failure, uncontrollable thirst, and hyperreninemia. Cessation of thirst with bilateral nephrectomy.", "content": "Renal failure, uncontrollable thirst, and hyperreninemia. Cessation of thirst with bilateral nephrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354481"}
{"pmid": "4354485", "title": "Snoring.", "content": "Snoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354485"}
{"pmid": "4354488", "title": "Computerized axial tomography of the head: the EMI-scanner, a new device for direct examination of the brain \"in vivo\". Special article.", "content": "Computerized axial tomography of the head: the EMI-scanner, a new device for direct examination of the brain \"in vivo\". Special article.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354488"}
{"pmid": "4354496", "title": "Cochlear summating potentials. Descriptive aspects.", "content": "Cochlear summating potentials. Descriptive aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354496"}
{"pmid": "4354497", "title": "Vestibular disturbances in clinical otosclerosis.", "content": "Vestibular disturbances in clinical otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354497"}
{"pmid": "4354489", "title": "Intraocular penetration of Ara A and idu-therapeutic implications in clinical herpetic uveitis.", "content": "Intraocular penetration of Ara A and idu-therapeutic implications in clinical herpetic uveitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354489"}
{"pmid": "4354490", "title": "Ophthalmic ointment.", "content": "Ophthalmic ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354490"}
{"pmid": "4354498", "title": "Cyclic AMP and calcium ions in mechanical and metabolic responses of smooth muscles; influence of some hormones and drugs.", "content": "Cyclic AMP and calcium ions in mechanical and metabolic responses of smooth muscles; influence of some hormones and drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354498"}
{"pmid": "4354499", "title": "Adrenergic, cholecystokinetic and morphine-induced effects on extra-hepatic biliary motility.", "content": "Adrenergic, cholecystokinetic and morphine-induced effects on extra-hepatic biliary motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354499"}
{"pmid": "4354500", "title": "The metabolic role of lecithin: cholesterol acyltransferase: perspectives form pathology.", "content": "The metabolic role of lecithin: cholesterol acyltransferase: perspectives form pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354500"}
{"pmid": "4354491", "title": "Surgery on only-hearing ears.", "content": "Surgery on only-hearing ears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354491"}
{"pmid": "4354502", "title": "Acute renal failure in obstetric septic shock. Current views on pathogenesis and management.", "content": "Acute renal failure in obstetric septic shock. Current views on pathogenesis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354502"}
{"pmid": "4354503", "title": "Detection of a single, metal-independent aminopeptidase activity in polymyxin-extracts from Escherichia coli B.", "content": "Detection of a single, metal-independent aminopeptidase activity in polymyxin-extracts from Escherichia coli B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354503"}
{"pmid": "4354504", "title": "Roentgen diagnosis of naso-pharyngeal masses.", "content": "Roentgen diagnosis of naso-pharyngeal masses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354504"}
{"pmid": "4354505", "title": "Chronic marijuana usage and sleep-wakefulness cycles in cats.", "content": "Chronic marijuana usage and sleep-wakefulness cycles in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354505"}
{"pmid": "4354506", "title": "Studies on dream recall in chronic schizophrenic patients after prefrontal lobotomy.", "content": "Studies on dream recall in chronic schizophrenic patients after prefrontal lobotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354506"}
{"pmid": "4354507", "title": "L-dopa and REM sleep in normal and mentally retarded subjects.", "content": "L-dopa and REM sleep in normal and mentally retarded subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354507"}
{"pmid": "4354508", "title": "Effects of alpha-methyltyrosine on REM sleep and brain amine levels in the cat.", "content": "Effects of alpha-methyltyrosine on REM sleep and brain amine levels in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354508"}
{"pmid": "4354509", "title": "A high activity divalent cation ATPase from the distal, caudal epididymis of bulls.", "content": "A high activity divalent cation ATPase from the distal, caudal epididymis of bulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354509"}
{"pmid": "4354511", "title": "Alkylated pyrimidine derivatives as antiviral agents. 3. Synthesis and antiviral effect of 5-ethyluracil nucleosides.", "content": "Alkylated pyrimidine derivatives as antiviral agents. 3. Synthesis and antiviral effect of 5-ethyluracil nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354511"}
{"pmid": "4354510", "title": "Alternate immunoprophylactic and biologic techniques in the control of viral respiratory tract diseases.", "content": "Alternate immunoprophylactic and biologic techniques in the control of viral respiratory tract diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354510"}
{"pmid": "4354501", "title": "Lipids in viruses.", "content": "Lipids in viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354501"}
{"pmid": "4354516", "title": "Respiratory syncytial and adenovirus infections of the lower respiratory tract in infanCY.", "content": "Respiratory syncytial and adenovirus infections of the lower respiratory tract in infanCY.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354516"}
{"pmid": "4354517", "title": "Chronic renal failure.", "content": "Chronic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354517"}
{"pmid": "4354533", "title": "Conversion of angiotensin 1 to angiotensin 2 in the isolated perfused dog lung.", "content": "Conversion of angiotensin 1 to angiotensin 2 in the isolated perfused dog lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354533"}
{"pmid": "4354534", "title": "Starvation and human slow-wave sleep.", "content": "Starvation and human slow-wave sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354534"}
{"pmid": "4354535", "title": "Observations on the growth of varicella-zoster virus in human diploid cells.", "content": "Observations on the growth of varicella-zoster virus in human diploid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354535"}
{"pmid": "4354536", "title": "Homogeneous murine myeloma protein-315 and spin-labeled DNP as a model system for spin-labeled hapten titration technique and spin immunoassay.", "content": "Homogeneous murine myeloma protein-315 and spin-labeled DNP as a model system for spin-labeled hapten titration technique and spin immunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354536"}
{"pmid": "4354537", "title": "Radioimmunoelectroosmophoresis, a technique combining immunoelectroosmophoresis with autoradiography; applications to virology.", "content": "Radioimmunoelectroosmophoresis, a technique combining immunoelectroosmophoresis with autoradiography; applications to virology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354537"}
{"pmid": "4354538", "title": "X-ray of the month.", "content": "X-ray of the month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354538"}
{"pmid": "4354542", "title": "When should you consider a cortisone prep?", "content": "When should you consider a cortisone prep?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354542"}
{"pmid": "4354544", "title": "Effect of catecholamines, histamine and oxyfedrine on isotonic contraction and cyclic AMP in the guinea-pig heart.", "content": "Effect of catecholamines, histamine and oxyfedrine on isotonic contraction and cyclic AMP in the guinea-pig heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354544"}
{"pmid": "4354553", "title": "Cross-species transmission of mammalian RNA tumor viruses.", "content": "Cross-species transmission of mammalian RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354553"}
{"pmid": "4354554", "title": "Methods of differentiation between virulent and attenuated strains of infectious canine hepatitis.", "content": "Methods of differentiation between virulent and attenuated strains of infectious canine hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354554"}
{"pmid": "4354560", "title": "Response of the eye to a flash of light.", "content": "Response of the eye to a flash of light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354560"}
{"pmid": "4354559", "title": "Structure-activity relationships for inhibitors of phosphodiesterase from erythrocytes and other tissues.", "content": "Structure-activity relationships for inhibitors of phosphodiesterase from erythrocytes and other tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354559"}
{"pmid": "4354561", "title": "Absent posterior arch of the atlas.", "content": "Absent posterior arch of the atlas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354561"}
{"pmid": "4354552", "title": "Pseudogout.", "content": "Pseudogout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354552"}
{"pmid": "4354564", "title": "Purine nucleotide synthesis in lymphoblasts cultured from normal subjects and a patient with Lesch-Nyhan syndrome.", "content": "Purine nucleotide synthesis in lymphoblasts cultured from normal subjects and a patient with Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354564"}
{"pmid": "4354565", "title": "Rat uterine contractility and the activities of uterine adenyl cyclase and phosphodiesterase during the estrus cycle.", "content": "Rat uterine contractility and the activities of uterine adenyl cyclase and phosphodiesterase during the estrus cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354565"}
{"pmid": "4354574", "title": "Muscle tone abnormality and tonic vibration reflex (TVR).", "content": "Muscle tone abnormality and tonic vibration reflex (TVR).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354574"}
{"pmid": "4354567", "title": "Chemotherapy of choriocarcinoma and related trophoblastic tumors in women.", "content": "Chemotherapy of choriocarcinoma and related trophoblastic tumors in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354567"}
{"pmid": "4354573", "title": "The kinetics of transmitter release in myasthenia gravis. 3. An electrophysiological analysis of the release of transmitter.", "content": "The kinetics of transmitter release in myasthenia gravis. 3. An electrophysiological analysis of the release of transmitter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354573"}
{"pmid": "4354575", "title": "Modulation of adenyl cyclase action in toad bladder by chlorpropamide: antagonism to prostaglandin E.", "content": "Modulation of adenyl cyclase action in toad bladder by chlorpropamide: antagonism to prostaglandin E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354575"}
{"pmid": "4354576", "title": "The action of reserpine on teleost melanophores.", "content": "The action of reserpine on teleost melanophores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354576"}
{"pmid": "4354566", "title": "Roy Hertz (1909- ).", "content": "Roy Hertz (1909- ).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354566"}
{"pmid": "4354577", "title": "Studies on the bradycardia induced by (-)- -trans-tetrahydrocannabinol in anesthetized dogs.", "content": "Studies on the bradycardia induced by (-)- -trans-tetrahydrocannabinol in anesthetized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354577"}
{"pmid": "4354578", "title": "Interaction of vasoactive agents and micro-emboli on the pulmonary circulation.", "content": "Interaction of vasoactive agents and micro-emboli on the pulmonary circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354578"}
{"pmid": "4354579", "title": "Acute effects of morphine on dopamine synthesis and release and tyrosine metabolism in the rat striatum.", "content": "Acute effects of morphine on dopamine synthesis and release and tyrosine metabolism in the rat striatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354579"}
{"pmid": "4354584", "title": "Overview of gestational trophoblastic neoplasia.", "content": "Overview of gestational trophoblastic neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354584"}
{"pmid": "4354585", "title": "Cardiogenic shock. Recent advances in pharmacologic management. II.", "content": "Cardiogenic shock. Recent advances in pharmacologic management. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354585"}
{"pmid": "4354586", "title": "Multiplication, O2 consumption and cytochrome oxidase activity of a cold-adapted L cell line.", "content": "Multiplication, O2 consumption and cytochrome oxidase activity of a cold-adapted L cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354586"}
{"pmid": "4354591", "title": "Synthesis of 2-hydroxy-ethynylestradiol and 4-hydroxy-ethynylestradiol.", "content": "Synthesis of 2-hydroxy-ethynylestradiol and 4-hydroxy-ethynylestradiol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354591"}
{"pmid": "4354593", "title": "The relationship between the viruses causing hepatitis and autoimmunity in liver disease.", "content": "The relationship between the viruses causing hepatitis and autoimmunity in liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354593"}
{"pmid": "4354596", "title": "Syndactyly in a German shepherd dog.", "content": "Syndactyly in a German shepherd dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354596"}
{"pmid": "4354597", "title": "Intranuclear fibrillar bundles in functioning beta-cell adenoma of pancreas.", "content": "Intranuclear fibrillar bundles in functioning beta-cell adenoma of pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354597"}
{"pmid": "4354598", "title": "Effect of cyclic 3'-5'-adenosine monophosphate and theophylline on renal function.", "content": "Effect of cyclic 3'-5'-adenosine monophosphate and theophylline on renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354598"}
{"pmid": "4354599", "title": "Reinvestigation of the anaerobic glycolytic potential of the regenerating rat liver.", "content": "Reinvestigation of the anaerobic glycolytic potential of the regenerating rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354599"}
{"pmid": "4354600", "title": "A review of clinical applications and methods for cholinesterase.", "content": "A review of clinical applications and methods for cholinesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354600"}
{"pmid": "4354601", "title": "Isoelectric focusing of human fetoprotein: an aid in purification and characterization of microheterogeneity.", "content": "Isoelectric focusing of human fetoprotein: an aid in purification and characterization of microheterogeneity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354601"}
{"pmid": "4354604", "title": "Circular dichroism studies of the conformation of synthetic peptides in the carboxyl-terminal region of cytochrome c.", "content": "Circular dichroism studies of the conformation of synthetic peptides in the carboxyl-terminal region of cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354604"}
{"pmid": "4354603", "title": "Yeast inorganic pyrophosphatase. II. Magnetic resonance and steady-state kinetic studies of metal ion and pyrophosphate analog binding.", "content": "Yeast inorganic pyrophosphatase. II. Magnetic resonance and steady-state kinetic studies of metal ion and pyrophosphate analog binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354603"}
{"pmid": "4354605", "title": "Proton magnetic resonance studies of horse cytochrome c.", "content": "Proton magnetic resonance studies of horse cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354605"}
{"pmid": "4354606", "title": "A molecular weight determination of the 16S ribosomal ribonucleic acid from Escherichia coli.", "content": "A molecular weight determination of the 16S ribosomal ribonucleic acid from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354606"}
{"pmid": "4354608", "title": "Magnetic resonance studies of substrate and inhibitor binding to porcine muscle adenylate kinase.", "content": "Magnetic resonance studies of substrate and inhibitor binding to porcine muscle adenylate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354608"}
{"pmid": "4354607", "title": "Effects of deoxyribonucleic acid and histone on the number and length of chains of poly(adenosine diphosphate-ribose).", "content": "Effects of deoxyribonucleic acid and histone on the number and length of chains of poly(adenosine diphosphate-ribose).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354607"}
{"pmid": "4354609", "title": "Kinetic effects of inorganic pyrophosphate analogs on several inorganic pyrophosphate hydrolyzing enzymes.", "content": "Kinetic effects of inorganic pyrophosphate analogs on several inorganic pyrophosphate hydrolyzing enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354609"}
{"pmid": "4354612", "title": "Estradiol receptors in benign and malignant disease of the breast.", "content": "Estradiol receptors in benign and malignant disease of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354612"}
{"pmid": "4354613", "title": "Free radicals and neoplasia--some experimental findings and some possible implications.", "content": "Free radicals and neoplasia--some experimental findings and some possible implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354613"}
{"pmid": "4354614", "title": "Calcium and gastrointestinal secretion.", "content": "Calcium and gastrointestinal secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354614"}
{"pmid": "4354616", "title": "Studies on the bacteriophage MS2. An internal nucleotide fragment resembling some ribosomal binding sites.", "content": "Studies on the bacteriophage MS2. An internal nucleotide fragment resembling some ribosomal binding sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354616"}
{"pmid": "4354617", "title": "Oxidative phosphorylation in bacteria which contain different cytochrome oxidases.", "content": "Oxidative phosphorylation in bacteria which contain different cytochrome oxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354617"}
{"pmid": "4354618", "title": "Studies on the mechanism of the oxygen-induced synthesis of cytochrome oxidase in yeast. Specific effects of benzimidazole on cytochrome-oxidase anabolism.", "content": "Studies on the mechanism of the oxygen-induced synthesis of cytochrome oxidase in yeast. Specific effects of benzimidazole on cytochrome-oxidase anabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354618"}
{"pmid": "4354619", "title": "The effect of fluoride on the spectral and catalytic properties of the three copper-containing oxidases.", "content": "The effect of fluoride on the spectral and catalytic properties of the three copper-containing oxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354619"}
{"pmid": "4354620", "title": "Microbial assimilation of methanol. The ethanol- and methanol-oxidizing enzymes of the yeast Candida boidinii.", "content": "Microbial assimilation of methanol. The ethanol- and methanol-oxidizing enzymes of the yeast Candida boidinii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354620"}
{"pmid": "4354621", "title": "Subcellular location of superoxide dismutase in spinach leaves and preparation and properties of crystalline spinach superoxide dismutase.", "content": "Subcellular location of superoxide dismutase in spinach leaves and preparation and properties of crystalline spinach superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354621"}
{"pmid": "4354622", "title": "Solubility requirements for cholesterol esters in human plasma: role of high density lipoprotein protein and phospholipids.", "content": "Solubility requirements for cholesterol esters in human plasma: role of high density lipoprotein protein and phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354622"}
{"pmid": "4354625", "title": "An enzyme variation in a case of congenital methemoglobinemia.", "content": "An enzyme variation in a case of congenital methemoglobinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354625"}
{"pmid": "4354624", "title": "Zollinger-Ellison syndrome.", "content": "Zollinger-Ellison syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354624"}
{"pmid": "4354626", "title": "Infective agents in the causation of Hodgkin's disease. A review of the epidemiological evidence.", "content": "Infective agents in the causation of Hodgkin's disease. A review of the epidemiological evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354626"}
{"pmid": "4354628", "title": "Afferent lung denervation by brief inhalation of steam.", "content": "Afferent lung denervation by brief inhalation of steam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354628"}
{"pmid": "4354629", "title": "Isomer subfractionation effects in the study of longer chain monoethylene fatty acids in hydrogenated oils.", "content": "Isomer subfractionation effects in the study of longer chain monoethylene fatty acids in hydrogenated oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354629"}
{"pmid": "4354630", "title": "The component triglycerides of rat adipose tissue. I. As studied after fractionation into classes by silver ion-thin layer chromatography.", "content": "The component triglycerides of rat adipose tissue. I. As studied after fractionation into classes by silver ion-thin layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354630"}
{"pmid": "4354631", "title": "Note on the activity of angiotensinase in exercise proteinuria.", "content": "Note on the activity of angiotensinase in exercise proteinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354631"}
{"pmid": "4354633", "title": "Whipple's disease.", "content": "Whipple's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354633"}
{"pmid": "4354632", "title": "Electron microscope studies on aldehyde-fixed, unstained microbial cells.", "content": "Electron microscope studies on aldehyde-fixed, unstained microbial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354632"}
{"pmid": "4354637", "title": "Studies on the antilipolytic effect of adenosine and related compounds in isolated fat cells.", "content": "Studies on the antilipolytic effect of adenosine and related compounds in isolated fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354637"}
{"pmid": "4354638", "title": "Frequency dependent decrease of quantal content in a drug-treated neuromuscular junction.", "content": "Frequency dependent decrease of quantal content in a drug-treated neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354638"}
{"pmid": "4354640", "title": "Michaelis-Menten kinetics of secretion of sympathetic neurotransmitter as a function of external calcium: effect of graded alpha adrenoceptor blockade.", "content": "Michaelis-Menten kinetics of secretion of sympathetic neurotransmitter as a function of external calcium: effect of graded alpha adrenoceptor blockade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354640"}
{"pmid": "4354639", "title": "Effects of antilipolytic drugs on cyclic 3',5'-AMP dependent protein kinase.", "content": "Effects of antilipolytic drugs on cyclic 3',5'-AMP dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354639"}
{"pmid": "4354641", "title": "Micropuncture investigations on the effect of angiotensin on the inorganic phosphate reabsorption in the proximal tubule of the rat.", "content": "Micropuncture investigations on the effect of angiotensin on the inorganic phosphate reabsorption in the proximal tubule of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354641"}
{"pmid": "4354642", "title": "Copper homeostasis in the mammalian system.", "content": "Copper homeostasis in the mammalian system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354642"}
{"pmid": "4354643", "title": "Microphysiology of vertebrate neuromuscular transmission.", "content": "Microphysiology of vertebrate neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354643"}
{"pmid": "4354634", "title": "Histochemical studies on thyroid adenoma built of C cells.", "content": "Histochemical studies on thyroid adenoma built of C cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354634"}
{"pmid": "4354635", "title": "The mode of action and clinical use of spirolactones.", "content": "The mode of action and clinical use of spirolactones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354635"}
{"pmid": "4354654", "title": "Spontaneous and virus induced transformation in cell culture.", "content": "Spontaneous and virus induced transformation in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354654"}
{"pmid": "4354656", "title": "Brain tumors during the first year of life.", "content": "Brain tumors during the first year of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354656"}
{"pmid": "4354655", "title": "Tissue response to a single intraperitoneal injection of various substances in rats.", "content": "Tissue response to a single intraperitoneal injection of various substances in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354655"}
{"pmid": "4354657", "title": "The inhibitory effect of diethylaminoethyl diphenylvalerate (SKF 525-A) on glucuronidation by cultures of rat hepatoma cells.", "content": "The inhibitory effect of diethylaminoethyl diphenylvalerate (SKF 525-A) on glucuronidation by cultures of rat hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354657"}
{"pmid": "4354659", "title": "Disorders due to enzyme defects in the red blood cell.", "content": "Disorders due to enzyme defects in the red blood cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354659"}
{"pmid": "4354660", "title": "Biology of the trophoblast.", "content": "Biology of the trophoblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354660"}
{"pmid": "4354661", "title": "Tumours of the central nervous system in Zambia.", "content": "Tumours of the central nervous system in Zambia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354661"}
{"pmid": "4354663", "title": "Enterotoxic diarrheal syndromes.", "content": "Enterotoxic diarrheal syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354663"}
{"pmid": "4354662", "title": "Prostaglandins and asthma.", "content": "Prostaglandins and asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354662"}
{"pmid": "4354664", "title": "Insulin receptors.", "content": "Insulin receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354664"}
{"pmid": "4354665", "title": "Review of reviews.", "content": "Review of reviews.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354665"}
{"pmid": "4354666", "title": "Experimental studies on cobalt cardiopathy.", "content": "Experimental studies on cobalt cardiopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354666"}
{"pmid": "4354668", "title": "Cytology of the corpus luteum.", "content": "Cytology of the corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354668"}
{"pmid": "4354670", "title": "The mystique of the herpesviruses.", "content": "The mystique of the herpesviruses. Probing the biologic mystique of the herpesvirus family, we find elements of antigenic similarity, the capacity of virions to persist within our cells in complete form, and the potential at some later time for these virions to undergo renewed replication. A venereal mode of transmission from one host to another may be characteristic of some of these viruses. Similar patterns of illness may be produced by several of the herpesviruses. Within the cellular framework of inflammation and necrosis which infective virus may evoke in the host, there may also reside the capability of neoplastic transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354670"}
{"pmid": "4354671", "title": "Some interface phenomena in parasitic protozoa and platyhelminths.", "content": "Some interface phenomena in parasitic protozoa and platyhelminths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354671"}
{"pmid": "4354685", "title": "A clinical comparison between monochrome color film and black and white RP-film as a universal x-ray film. A preliminary report.", "content": "A clinical comparison between monochrome color film and black and white RP-film as a universal x-ray film. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354685"}
{"pmid": "4354692", "title": "An electron microscopic study of synaptic organization in the medial superior olive of normal and experimental chinchillas.", "content": "An electron microscopic study of synaptic organization in the medial superior olive of normal and experimental chinchillas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354692"}
{"pmid": "4354694", "title": "The N6-(dimethylamino)methylene derivative of 9-beta-D-arabinofuranosyladenine as an antiviral agent.", "content": "The N6-(dimethylamino)methylene derivative of 9-beta-D-arabinofuranosyladenine as an antiviral agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354694"}
{"pmid": "4354693", "title": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 1. Bisalkamine esters of fluorenone-, fluorenol-, and fluorenedicarboxylic acids.", "content": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 1. Bisalkamine esters of fluorenone-, fluorenol-, and fluorenedicarboxylic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354693"}
{"pmid": "4354697", "title": "Regeneration of the endometrium in rabbits after curettage. II. Pretreatment with progesterone.", "content": "Regeneration of the endometrium in rabbits after curettage. II. Pretreatment with progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354697"}
{"pmid": "4354696", "title": "Regeneration of the endometrium in rabbits after curettage. I. Pretreatment with estrogens.", "content": "Regeneration of the endometrium in rabbits after curettage. I. Pretreatment with estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354696"}
{"pmid": "4354695", "title": "Phenocopies.", "content": "Phenocopies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354695"}
{"pmid": "4354700", "title": "Malignant uterine mesotheliomas in squirrel monkeys following diethylstilbestrol administration.", "content": "Malignant uterine mesotheliomas in squirrel monkeys following diethylstilbestrol administration. 10 adult female squirrel monkeys were implanted subcutaneously with 4 60 mg pellets of diethylstilbestrol (DES); 4 animals were implanted with cholesterol pellets to serve as controls.  Animals were killed at 5, 9, 11, and 14 months after insertion of pellets.  All animals implanted with DES had evidence of extreme estrogenic stimulation, including marked edema of the labia, heavy vaginal cornification, and enlargement of the uterine corpus.  There were several stages of uterine lesions, in general in proportion to the duration of treatment.  The less advanced lesions were restricted to hyperplasia and hyperthrophy of the serosal cells.  In more advanced lesions the myometrium was infiltrated; in the most advanced cases there was invasion of the endometrium.  The 7 most advanced uterine tumors were classified as malignant mesotheliomas.  Cholesterol-treated controls did not have any significant lesions.  These observations indicate that DES is carcinogenic in the squirrel monkey, as it has been demonstrated to be in other lower mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354700"}
{"pmid": "4354701", "title": "Use of neotropical rodents in protein efficiency studies.", "content": "Use of neotropical rodents in protein efficiency studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354701"}
{"pmid": "4354702", "title": "An automatic data processing system for long-term toxicological study utilizing the beagle dog.", "content": "An automatic data processing system for long-term toxicological study utilizing the beagle dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354702"}
{"pmid": "4354703", "title": "Serum thyroxine levels in the perinatal guinea pig (Cavia porcellus).", "content": "Serum thyroxine levels in the perinatal guinea pig (Cavia porcellus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354703"}
{"pmid": "4354704", "title": "Tuberculin testing in rhesus monkeys (Macaca mulatta): a comparative study using experimentally sensitized animals.", "content": "Tuberculin testing in rhesus monkeys (Macaca mulatta): a comparative study using experimentally sensitized animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354704"}
{"pmid": "4354705", "title": "Stability of resistance-susceptibility characteristics in 2 inbred mouse strains.", "content": "Stability of resistance-susceptibility characteristics in 2 inbred mouse strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354705"}
{"pmid": "4354706", "title": "Characterization of a fibroma virus isolated from naturally-occurring skin tumors in domestic rabbits.", "content": "Characterization of a fibroma virus isolated from naturally-occurring skin tumors in domestic rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354706"}
{"pmid": "4354707", "title": "Neoplasms and proliferative lesions in 1065 nonhuman primate necropsies.", "content": "Neoplasms and proliferative lesions in 1065 nonhuman primate necropsies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354707"}
{"pmid": "4354708", "title": "Edentate diets. I. Armadillos.", "content": "Edentate diets. I. Armadillos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354708"}
{"pmid": "4354709", "title": "Edentate diets. II. Two-toed sloths.", "content": "Edentate diets. II. Two-toed sloths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354709"}
{"pmid": "4354710", "title": "Repair of a mandibular fracture in an irradiated monkey using intraoral immobilization and intraosseous metal mesh fixation.", "content": "Repair of a mandibular fracture in an irradiated monkey using intraoral immobilization and intraosseous metal mesh fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354710"}
{"pmid": "4354711", "title": "A vacuum-assisted technic for repetitive blood sampling in the rat.", "content": "A vacuum-assisted technic for repetitive blood sampling in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354711"}
{"pmid": "4354712", "title": "Technic for collecting blood from neonatal rats.", "content": "Technic for collecting blood from neonatal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354712"}
{"pmid": "4354713", "title": "The use of succinylcholine in the handling and restraint of rhesus monkeys (Macaca mulatta).", "content": "The use of succinylcholine in the handling and restraint of rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354713"}
{"pmid": "4354714", "title": "Spontaneous Lancefield group G streptococcal infection in a random source cat colony.", "content": "Spontaneous Lancefield group G streptococcal infection in a random source cat colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354714"}
{"pmid": "4354716", "title": "A simplified technic for preparing sterile chicken serum.", "content": "A simplified technic for preparing sterile chicken serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354716"}
{"pmid": "4354715", "title": "A clinical laboratory study of conditioned mongrel dogs and Laborador retrievers.", "content": "A clinical laboratory study of conditioned mongrel dogs and Laborador retrievers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354715"}
{"pmid": "4354717", "title": "Comparative organ weights for 8 standardized wild rodent species.", "content": "Comparative organ weights for 8 standardized wild rodent species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354717"}
{"pmid": "4354718", "title": "Baseline blood determinations of the Taiwan macaque (Macaca cyclopis).", "content": "Baseline blood determinations of the Taiwan macaque (Macaca cyclopis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354718"}
{"pmid": "4354719", "title": "A case of spontaneous congenital pyloric stenosis in a rabbit.", "content": "A case of spontaneous congenital pyloric stenosis in a rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354719"}
{"pmid": "4354720", "title": "Long-term rabbit restraint--a simple method.", "content": "Long-term rabbit restraint--a simple method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354720"}
{"pmid": "4354722", "title": "Enzyme induction by viruses.", "content": "Enzyme induction by viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354722"}
{"pmid": "4354726", "title": "Neurotropic viruses and the developing brain.", "content": "Neurotropic viruses and the developing brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354726"}
{"pmid": "4354727", "title": "Purification of 9 -tetrahydrocannabinol, an active constituent of marihuana, by accelerated microparticulate gel chromatography.", "content": "Purification of 9 -tetrahydrocannabinol, an active constituent of marihuana, by accelerated microparticulate gel chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354727"}
{"pmid": "4354728", "title": "Electroencephalography.", "content": "Electroencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354728"}
{"pmid": "4354731", "title": "On the pathogensis of renovascular hypertension.", "content": "On the pathogensis of renovascular hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354731"}
{"pmid": "4354732", "title": "Adrenal response to synthetic adrenocorticotrophic hormone during pregnancy and after delivery, with special reference to pre-eclamptic and hypertensive pregnancy.", "content": "Adrenal response to synthetic adrenocorticotrophic hormone during pregnancy and after delivery, with special reference to pre-eclamptic and hypertensive pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354732"}
{"pmid": "4354733", "title": "Long-chain acyl-CoA synthetase activity in blood platelets and some human tissues.", "content": "Long-chain acyl-CoA synthetase activity in blood platelets and some human tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354733"}
{"pmid": "4354734", "title": "Bluetongue virus.", "content": "Bluetongue virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354734"}
{"pmid": "4354736", "title": "Biological significance of molecular chirality in energy balance and metabolism.", "content": "Biological significance of molecular chirality in energy balance and metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354736"}
{"pmid": "4354737", "title": "The results of prophylaxis of endemic cretinism with iodized oil in rural Andean Ecuador.", "content": "The results of prophylaxis of endemic cretinism with iodized oil in rural Andean Ecuador.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354737"}
{"pmid": "4354738", "title": "Increased aldosterone secretion during sodium depletion with inhibition of renin release.", "content": "Increased aldosterone secretion during sodium depletion with inhibition of renin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354738"}
{"pmid": "4354739", "title": "Some parameters relevant to affinity chromatography on immobilized nucleotides.", "content": "Some parameters relevant to affinity chromatography on immobilized nucleotides. 1. The suitability of cellulose and Sepharose as supports for affinity chromatography of two groups of cofactor-linked enzymes, dehydrogenases and kinases, was examined. Sepharose was found to be superior. 2. The selective capacities of the columns were measured by frontal analysis and are discussed in relation to the nucleotide contents. 3. The effect of various concentrations of enzyme and of non-specific protein on the performance of the affinity columns, and the effects of equilibration time, flow rate, sample volume and dilution of the nucleotide were examined. 4. The effect of interposing polymethylene and polyglycine extension arms between the matrix backbone and the nucleotide was investigated for several cofactor-dependent enzymes. Maximum binding was observed with an extension arm 0.8-1nm long.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354739"}
{"pmid": "4354740", "title": "Affinity chromatography of lactate dehydrogenase on immobilized nucleotides.", "content": "Affinity chromatography of lactate dehydrogenase on immobilized nucleotides. The interaction of two isoenzymes of lactate dehydrogenase from pig heart muscle (H(4)) and rabbit skeletal muscle (M(4)), with immobilized nucleotides was examined: the effects of pH and temperature on the binding of lactate dehydrogenase were studied with immobilized NAD(+) matrices. The influence of substrate, product and sulphite on the binding of heart muscle lactate dehydrogenase to immobilized NAD(+) was investigated. The interaction of both lactate dehydrogenase isoenzymes with immobilized pyridine and adenine nucleotides and their derivatives were measured. The effects of these parameters on the interaction of lactate dehydrogenase with immobilized nucleotides were correlated with the known kinetic and molecular properties of the enzymes in free solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354740"}
{"pmid": "4354742", "title": "Adenosine 3':5'-cyclic monophosphate-binding protein from the cellular slime mould Dictyostelium discoideum.", "content": "Adenosine 3':5'-cyclic monophosphate-binding protein from the cellular slime mould Dictyostelium discoideum. During the differentiation of myxamoebae of Dictyostelium discoideum strain Ax-2 grown in axenic medium there is a seven- to ten-fold increase in the specific activity of cyclic AMP-binding protein(s). Evidence is presented for the belief that cyclic AMP phosphodiesterase and cyclic AMP-binding protein are distinct molecular species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354742"}
{"pmid": "4354741", "title": "The mechanism of inhibition of rat liver tryptophan pyrrolase activity by 4-hydroxypyrazolo(3,4-d)pyrimidine (Allopurinol).", "content": "The mechanism of inhibition of rat liver tryptophan pyrrolase activity by 4-hydroxypyrazolo(3,4-d)pyrimidine (Allopurinol). 1. Allopurinol (4-hydroxypyrazolo[3,4-d]pyrimidine) selectively inhibits the apotryptophan pyrrolase activity in homogenates of rat liver in vitro and after intraperitoneal administration. The inhibition is abolished by an excess of haematin. The allopurinol metabolite alloxanthine has no effect on the pyrrolase activity in vitro or after administration. Allopurinol also inhibits the activation of the enzyme in vitro by ascorbate, ethanol plus NAD(+), NADH, hypoxanthine or xanthine. It is suggested that these agents cause the conversion of a latent form of the pyrrolase into the apoenzyme, and that xanthine oxidase is not involved in this process. 2. The raised total pyrrolase activity observed after the administration of cortisol, cyclic AMP, tryptophan, salicylate or ethanol is lowered by allopurinol in vitro to the corresponding holoenzyme values. A similar effect is observed when allopurinol is administered shortly before cortisol or cyclic AMP. Pretreatment of rats with allopurinol completely prevents the enhancement of the pyrrolase activities by tryptophan, salicylate or ethanol. 3. It is suggested that allopurinol inhibits rat liver tryptophan pyrrolase activity in vitro and after administration by preventing the conjugation of the apoenzyme with its haem activator. The possible usefulness of combined allopurinol-tryptophan therapy of affective disorders is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354741"}
{"pmid": "4354743", "title": "Inosine 5'-monophosphate dehydrogenase of Escherichia coli K12: the nature of the inhibition by guanosine 5'-monophosphate.", "content": "Inosine 5'-monophosphate dehydrogenase of Escherichia coli K12: the nature of the inhibition by guanosine 5'-monophosphate. When IMP is the variable substrate, IMP dehydrogenase (EC 1.2.1.14) gives non-linear Lineweaver-Burk plots in the presence of GMP. At 0.1mm-GMP the Hill coefficient n=1.15 and at 0.2mm-GMP n=1.34. In the absence of GMP n=1.0. The fact that n exceeds 1.0 in the presence of GMP indicates that the enzyme possesses regulatory (allosteric) properties. The inhibition by GMP is competitive with respect to IMP and non-competitive with respect to NAD(+).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354743"}
{"pmid": "4354744", "title": "Infection with E.B. virus.", "content": "Infection with E.B. virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354744"}
{"pmid": "4354747", "title": "Late clinical and roentgen observations following Thorotrast administration.", "content": "Late clinical and roentgen observations following Thorotrast administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354747"}
{"pmid": "4354746", "title": "The radiological and scintigraphic investigation of spontaneous hypoglycaemia.", "content": "The radiological and scintigraphic investigation of spontaneous hypoglycaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354746"}
{"pmid": "4354749", "title": "Sensitivity to mutagens of Rumex acetosa chromosomes.", "content": "Sensitivity to mutagens of Rumex acetosa chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354749"}
{"pmid": "4354751", "title": "Inhibition of angiotensin-coverting enzyme by analogs of peptides from Bothrops jararaca venom.", "content": "Inhibition of angiotensin-coverting enzyme by analogs of peptides from Bothrops jararaca venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354751"}
{"pmid": "4354750", "title": "Enhancement of ethylemethane sulfunate-induced frequency in Drosophila by dimethyl sulphoxide.", "content": "Enhancement of ethylemethane sulfunate-induced frequency in Drosophila by dimethyl sulphoxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354750"}
{"pmid": "4354753", "title": "Phosphatases. IX. Differences in sialic acid content of rat liver alkaline phosphatase isoenzymes.", "content": "Phosphatases. IX. Differences in sialic acid content of rat liver alkaline phosphatase isoenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354753"}
{"pmid": "4354752", "title": "Isolation of different thermophilic enzymes from Bacillus stearothermophilus.", "content": "Isolation of different thermophilic enzymes from Bacillus stearothermophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354752"}
{"pmid": "4354754", "title": "Enzyme-polymer adducts of aldolase, glyceraldehydephosphate dehydrogenase, and fructosediphosphatase.", "content": "Enzyme-polymer adducts of aldolase, glyceraldehydephosphate dehydrogenase, and fructosediphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354754"}
{"pmid": "4354755", "title": "Effect of chemical sympathectomy on pressor responses to norepinephrine, angiotensin and tyramine.", "content": "Effect of chemical sympathectomy on pressor responses to norepinephrine, angiotensin and tyramine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354755"}
{"pmid": "4354757", "title": "Digestive physiology with reference to enzymes in the alimentary canal of coridius janus Fabr. (Heteroptera: Dinidoridae).", "content": "Digestive physiology with reference to enzymes in the alimentary canal of coridius janus Fabr. (Heteroptera: Dinidoridae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354757"}
{"pmid": "4354756", "title": "The lung in relation to vasoactive hormones.", "content": "The lung in relation to vasoactive hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354756"}
{"pmid": "4354758", "title": "Hormone: receptor interactions. Biological activities of (phenylalanine, norvaline)-adrenocorticotropin-(1-24)-tetrakosipeptide and its 4,5-dehydro-4,5-ditritio-norvaline analogue in isolated rat lipocytes and adrenal cortex cells: lipolysis, corticosterone and cyclic adenosine-3',5'-monophosphate production.", "content": "Hormone: receptor interactions. Biological activities of (phenylalanine, norvaline)-adrenocorticotropin-(1-24)-tetrakosipeptide and its 4,5-dehydro-4,5-ditritio-norvaline analogue in isolated rat lipocytes and adrenal cortex cells: lipolysis, corticosterone and cyclic adenosine-3',5'-monophosphate production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354758"}
{"pmid": "4354759", "title": "Observations in an aftercare group.", "content": "Observations in an aftercare group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354759"}
{"pmid": "4354761", "title": "Simultaneous quantitative comparison of the optical changes at 700 nm (p700) and electron spin resonance signals in system I of green plant photosynthesis.", "content": "Simultaneous quantitative comparison of the optical changes at 700 nm (p700) and electron spin resonance signals in system I of green plant photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354761"}
{"pmid": "4354762", "title": "Myasthenia gravis.", "content": "Myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354762"}
{"pmid": "4354763", "title": "Chloroethyl-cyclohexyl-nitrosourea (CCNU) in the treatment of malignant brain tumors.", "content": "Chloroethyl-cyclohexyl-nitrosourea (CCNU) in the treatment of malignant brain tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354763"}
{"pmid": "4354764", "title": "Postoperative intracavitary chemotherapy of malignant gliomas. A preliminary study using methotrexate.", "content": "Postoperative intracavitary chemotherapy of malignant gliomas. A preliminary study using methotrexate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354764"}
{"pmid": "4354765", "title": "Ventriculoatrial shunt blockage by previous positive contrast ventriculography.", "content": "Ventriculoatrial shunt blockage by previous positive contrast ventriculography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354765"}
{"pmid": "4354767", "title": "Relationship of end-plate morphology to junctional chemosensitivity.", "content": "Relationship of end-plate morphology to junctional chemosensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354767"}
{"pmid": "4354766", "title": "Analysis of Mauthner cell responses to iontophoretically delivered pulses of GABA, glycine and L-glutamate.", "content": "Analysis of Mauthner cell responses to iontophoretically delivered pulses of GABA, glycine and L-glutamate. 1. The intracellularly recorded responses of goldfish Mauthner neurones to iontophoretically applied pulses of amino acids have been analysed: their time courses have been compared with each other, and with those predicted from diffusion theory.2. The rise time of the response to GABA is slower than that to glycine or L-glutamate. The response curves of the latter substances were very similar, and unlike that of GABA were markedly affected by increasing the distance of pipette-tip from the membrane. The results suggest that the time course of the responses to glycine and L-glutamate are determined mainly by free diffusion in the brain tissue (at least within about 200 mum of the cell), while that to GABA must be rate-limited by other factors, e.g. drug-receptor activation time.3. The possibility that the responses are influenced by some desensitizing process was investigated by applying a second (test) drug pulse during the response to a prior conditioning one. In the case of glycine and of L-glutamate there was no attenuation of the response to a second pulse at any time. With GABA, however, the second response was reduced during the period of the conditioning response; the reduction was progressively less marked the later the test pulse occurred. A similar effect with GABA was seen when glycine was used as the test pulse. The responses to long-maintained drug pulses also indicated that for GABA, but not for glycine or glutamate, there seems to be some desensitizing process present.4. Calculated time courses of responses to brief pulses of glycine and of L-glutamate (based upon diffusion theory) differed somewhat from the observed curves, largely during the falling phase. However, when the calculations were based upon second-order reactions (two molecules of drug per receptor) the diffusion model gave results very like the observed ones.5. Possible implications of these results for the role these three amino acids may have as neuro-transmitters are mentioned.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354766"}
{"pmid": "4354760", "title": "Absorption of fortification iron by the rat: comparison of type and level of iron incorporated into mixed grain cereal.", "content": "Absorption of fortification iron by the rat: comparison of type and level of iron incorporated into mixed grain cereal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354760"}
{"pmid": "4354769", "title": "The effect of nicotinic acid and alloxan on the secretion of electrolytes and amylase by the isolated saline perfused pancreas of the cat.", "content": "The effect of nicotinic acid and alloxan on the secretion of electrolytes and amylase by the isolated saline perfused pancreas of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354769"}
{"pmid": "4354768", "title": "Spontaneous quantal transmitter release: a statistical analysis and some implications.", "content": "Spontaneous quantal transmitter release: a statistical analysis and some implications. 1. Miniature end-plate potentials (m.e.p.p.s) were intra- and extracellularly recorded from neuromuscular junctions in rat phrenic nerve-diaphragm preparations in vitro.2. Statistical analysis of the intervals between m.e.p.p.s showed that when the mean number of events in time t was plotted as a function of the variance of the events in time t there was a significant deviation from the straight line relationship expected for a Poisson process. Computer simulation showed that this deviation is explicable if release was generated by the random phasing of the activity of a number of releasing sites.3. There was no indication that release of one quantum influences the probability of release of remaining quanta (drag, clustering). It is suggested that m.e.p.p.s whose amplitude is larger than the mode result from the release of the contents of vesicles whose volume is also supramodal.4. The effects of depolarization of nerve terminals upon the variance-mean curve suggest an increase in the activity of sites rather than an increase in their number.5. Statistical analysis indicated at least 200 +/- 100 (mean +/- 1 S.E.) releasing sites. This number is of the same order as the number of sites of vesicle aggregation and presynaptic membrane density seen in electron micrographs of nerve terminals of this preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354768"}
{"pmid": "4354770", "title": "The membrane effects, and sensitivity to strychnine, of neural inhibition of the Mauthner cell, and its inhibition by glycine and GABA.", "content": "The membrane effects, and sensitivity to strychnine, of neural inhibition of the Mauthner cell, and its inhibition by glycine and GABA. 1. Anionic conductance changes in Mauthner neurones of goldfish were measured during synaptically evoked inhibition and inhibition caused by iontophoretic application of the putative inhibitory transmitters glycine and gamma-aminobutyric acid (GABA).2. The effects of either amino acid were indistinguishable from those of the neural inhibitory transmitter(s). The membrane permeability during the neural or drug response was increased to Br(-), Cl(-), I(-), SCN(-), NO(3) (-), ClO(3) (-), and formate (HCOO(-)), but not to HCO(3) (-), BrO(3) (-), IO(3) (-), SO(4) (-), HPO(4) (-), H(2)PO(4) (-), acetate and citrate.3. Strychnine was injected intramuscularly, iontophoretically, or applied topically to the exposed brain in order to compare quantitatively its ability to prevent inhibition evoked by synaptic activation and by pharmacological means. Inhibitions were measured by the increase in membrane conductance.4. Strychnine, at concentrations just adequate to block completely the late collateral inhibition (LCI) and crossed VIII nerve inhibition, had little effect on the pharmacological inhibition caused by glycine, and sometimes there was no detectable effect at all. In one experiment even a local iontophoretic application of strychnine in a sufficient dose to diffuse over the cell and block the LCI almost completely, merely halved the effect of a small dose of glycine applied to the same localized region of the membrane.5. Higher concentrations of strychnine than those necessary to block synaptically evoked inhibition would reduce the effect of glycine but not that of GABA. The evidence indicated that any apparent effect of strychnine upon GABA could be explained by displacement of the GABA-containing iontophoretic pipette.6. The glycine-blocking action of iontophoretic pulses of strychnine was of relatively very slow onset and long duration compared to the effects of pulses of glycine and GABA.7. These findings can be interpreted as either (1) strychnine has a presynaptic action, preventing the release of inhibitory neurotransmitter, in addition to its less potent post-synaptic one in blocking pharmacological inhibition, or (2) strychnine acts entirely post-synaptically, but the physiological transmitter action differs from that of glycine and GABA in being considerably more sensitive to strychnine antagonism. In either case, the use of strychnine as evidence for the claim that glycine is an inhibitory neurotransmitter at the Mauthner cell is questionable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354770"}
{"pmid": "4354772", "title": "Correlation of the clinical response to ACTH treatment with the endocrine status in myasthenia gravis.", "content": "Correlation of the clinical response to ACTH treatment with the endocrine status in myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354772"}
{"pmid": "4354771", "title": "Small cell carcinoma of the lung. Clinicopathological studies.", "content": "Small cell carcinoma of the lung. Clinicopathological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354771"}
{"pmid": "4354773", "title": "Primary mucinous adenocarcinoma of the urinary bladder.", "content": "Primary mucinous adenocarcinoma of the urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354773"}
{"pmid": "4354775", "title": "Buoyant densities of mitochondrial DNA from tumour and normal tissues.", "content": "Buoyant densities of mitochondrial DNA from tumour and normal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354775"}
{"pmid": "4354777", "title": "Beclomethasone aerosol in childhood asthma.", "content": "Beclomethasone aerosol in childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354777"}
{"pmid": "4354779", "title": "Control of fetal lung development in the rabbit.", "content": "Control of fetal lung development in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354779"}
{"pmid": "4354778", "title": "Beclomethasone dipropionate aerosol in childhood asthma.", "content": "Beclomethasone dipropionate aerosol in childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354778"}
{"pmid": "4354780", "title": "Effect of human growth hormone treatment on adipose tissue in children.", "content": "Effect of human growth hormone treatment on adipose tissue in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354780"}
{"pmid": "4354781", "title": "Serological studies in asymptomatic congenital cytomegalovirus infection.", "content": "Serological studies in asymptomatic congenital cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354781"}
{"pmid": "4354783", "title": "Action of propranolol on lipolysis induced by catecholamine, dibutyryl cyclic AMP and serum.", "content": "Action of propranolol on lipolysis induced by catecholamine, dibutyryl cyclic AMP and serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354783"}
{"pmid": "4354784", "title": "Effect of intracellular accumulation of inert carbon particles on the cytochromes P-450 and b5 levels of rat liver microsomes.", "content": "Effect of intracellular accumulation of inert carbon particles on the cytochromes P-450 and b5 levels of rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354784"}
{"pmid": "4354785", "title": "Effects of sodium salicylate and acetylsalicylic acid on cyclic 3',5'-AMP-dependent protein kinase.", "content": "Effects of sodium salicylate and acetylsalicylic acid on cyclic 3',5'-AMP-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354785"}
{"pmid": "4354786", "title": "Cytochrome c stimulated oxidation of ethanol by liver mitochondria.", "content": "Cytochrome c stimulated oxidation of ethanol by liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354786"}
{"pmid": "4354787", "title": "Selective inhibition of nicotinamide adenine dinucleotide dependent oxidations by piperazinothioureas.", "content": "Selective inhibition of nicotinamide adenine dinucleotide dependent oxidations by piperazinothioureas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354787"}
{"pmid": "4354788", "title": "Comparative study of cytochromes between virus-transformed and untransformed cells.", "content": "Comparative study of cytochromes between virus-transformed and untransformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354788"}
{"pmid": "4354789", "title": "Studies on the activation of purified mitochondrial ATPase by phospholipids.", "content": "Studies on the activation of purified mitochondrial ATPase by phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354789"}
{"pmid": "4354790", "title": "Energy conservation capacity and morphological integrity of mitochondria in hypotonically treated rabbit epididymal spermatozoa.", "content": "Energy conservation capacity and morphological integrity of mitochondria in hypotonically treated rabbit epididymal spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354790"}
{"pmid": "4354791", "title": "Low-temperature spectral properties of the respiratory chain cytochromes of mitochondria from Crithidia fasciculata.", "content": "Low-temperature spectral properties of the respiratory chain cytochromes of mitochondria from Crithidia fasciculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354791"}
{"pmid": "4354792", "title": "Oxidative phosphorylation and effects of aerobic conditions on Rhodopseudomonas viridis.", "content": "Oxidative phosphorylation and effects of aerobic conditions on Rhodopseudomonas viridis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354792"}
{"pmid": "4354793", "title": "Cyanide-resistant respiration and a branched cytochrome system in Kinetoplastidae.", "content": "Cyanide-resistant respiration and a branched cytochrome system in Kinetoplastidae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354793"}
{"pmid": "4354794", "title": "Pigment content and molar extinction coefficients of photochemical reaction centers from Rhodopseudomonas spheroides.", "content": "Pigment content and molar extinction coefficients of photochemical reaction centers from Rhodopseudomonas spheroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354794"}
{"pmid": "4354795", "title": "The oxidation-reduction potential of membrane-bound chloroplast plastocyanin and cytochrome f.", "content": "The oxidation-reduction potential of membrane-bound chloroplast plastocyanin and cytochrome f.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354795"}
{"pmid": "4354796", "title": "Evidence for the identity of P430 of Photosystem I and chloroplast-bound iron-sulfur protein.", "content": "Evidence for the identity of P430 of Photosystem I and chloroplast-bound iron-sulfur protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354796"}
{"pmid": "4354798", "title": "Purine nucleotide biosynthesis in gastrointestinal mucosa.", "content": "Purine nucleotide biosynthesis in gastrointestinal mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354798"}
{"pmid": "4354797", "title": "Anion-exchange chromatography on reversed-phase columns: isolation and assay of nucleosides, nucleotides, and oligonucleotides from nucleic acids and from cytoplasm.", "content": "Anion-exchange chromatography on reversed-phase columns: isolation and assay of nucleosides, nucleotides, and oligonucleotides from nucleic acids and from cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354797"}
{"pmid": "4354800", "title": "Characterization of angiotensin receptors in vascular and intestinal smooth muscles.", "content": "Characterization of angiotensin receptors in vascular and intestinal smooth muscles. 1. A series of analogues of angiotensin II (AT(II)) has been used in the present experiments to characterize receptors for AT(II) in intestinal (rat stomach strip, rat colon) and vascular (rabbit aorta) smooth muscles. Two types of compounds have been chosen: (a) agonists with reduced potency, in which 4-Tyr, 6-His or 7-Pro had been substituted with L-Ala or with Gly and 1-amino-cyclopentane carboxylic acid (Acpc) and (b) competitive antagonists (8-Gly-AT(II), 8-Leu-AT(II)).2. Replacement of 4-Tyr, 6-His and 7-Pro with L-Ala decreases the potency, but does not influence the maximum effect of the analogue, while substitution of the same residue with Gly and Acpc reduces both potency and maximum effect.3. Compounds showing full size maximum responses were chosen to establish the following order of potency on the three preparations: AT(II)>4-Phe-AT(II)>7-Ala-AT(II)>6-Ala-AT(II)>4-Ala-AT(II).4. The four derivatives of AT(II) were completely inactive on tissues desensitized with AT(II). The responses to 5-hydroxytryptamine, acetylcholine and noradrenaline were not significantly modified, except for the rat colon.5. pA(2) values for the two competitive antagonists against AT(II) and 4-Phe-AT(II) were estimated in the three preparations by the use of the cascade superfusion technique. For comparison, pA(2) values were also estimated in rat stomach strips and rabbit aortas suspended in a normal organ bath, according to the method of Schild (1947). The similarities of the pA(2) values obtained in two series of experiments indicate that (a) the cascade superfusion technique is suitable for this type of study and (b) the receptor for AT(II) in the three tissues may be the same.6. It is suggested that receptors for AT(II) in intestinal and vascular smooth muscles may be the same, because (a) the order of potency of various agonists follows the same pattern, (b) the agonists are inactive on tissues desensitized with AT(II), (c) pA(2) values for competitive antagonists are similar in the three preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354800"}
{"pmid": "4354799", "title": "Interaction between picrotoxin and 5-hydroxytryptamine in the superior cervical ganglion of the cat.", "content": "Interaction between picrotoxin and 5-hydroxytryptamine in the superior cervical ganglion of the cat. 1. Electrophysiological techniques were utilized to study the actions of 5-hydroxytryptamine (5-HT) and picrotoxin on the superior cervical ganglion of the cat.2. The intra-arterial administration of 5-HT to the ganglion elicited both depressant and excitatory actions. In low doses (0.01-0.5 mug) the amine produced a depression of ganglionic transmission. In larger doses (2-50 mug) it produced an excitation of ganglion cells (early discharge) and an initial enhancement of transmission, which was followed by depression. Picrotoxin (25-500 mug, i.a.) blocked the initial excitatory effects of 5-HT but did not block the depression. Picrotoxin did not antagonize the excitatory actions of injected cholinomimetic agents or potassium chloride.3. In ganglia conditioned by repetitive stimulation of the preganglionic nerve (30 Hz for 30 s) 5-HT also elicited a late-occurring and very prolonged discharge on certain postganglionic nerves (;spinal') but not on others (external carotid). The late discharge was only partially depressed by picrotoxin.4. Recordings from the surface of the superior cervical ganglion revealed that 5-HT produced three types of ganglionic potentials: (1) an initial transient depolarization which coincided with the early discharge, (2) a late-occurring, prolonged depolarization which coincided with the late discharge, and (3) a hyperpolarization which in some experiments accompanied the depression of transmission. The late depolarization and hyperpolarization were not observed in every experiment. Picrotoxin (25-500 mug) blocked the initial depolarization, but did not block the late depolarization or the hyperpolarization.5. It is concluded the 5-HT can produce three distinct responses in the superior cervical ganglion: a depressant effect and two types of excitation. It seems likely that depression and excitation occur via the activation of different receptors, since picrotoxin selectively blocks the latter. The finding that picrotoxin is a 5-HT antagonist in peripheral ganglia raises the possibility that picrotoxin might also influence tryptaminergic mechanisms in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354799"}
{"pmid": "4354801", "title": "The effect of glibenclamide on two enzymes important in gluconeogenesis.", "content": "The effect of glibenclamide on two enzymes important in gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354801"}
{"pmid": "4354802", "title": "Potentiation by angiotensin II of noradrenaline-induced contractions of a rabbit isolated thoracic aorta.", "content": "Potentiation by angiotensin II of noradrenaline-induced contractions of a rabbit isolated thoracic aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354802"}
{"pmid": "4354803", "title": "Atropine sensitivity of transmission and facilitation in the rabbit superior cervical ganglion.", "content": "Atropine sensitivity of transmission and facilitation in the rabbit superior cervical ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354803"}
{"pmid": "4354804", "title": "Drugs influencing plasma and brain tryptophan.", "content": "Drugs influencing plasma and brain tryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354804"}
{"pmid": "4354806", "title": "Plasma renin and the antihypertensive effect of 1-Sar-8-Ala-angiotensin II.", "content": "Plasma renin and the antihypertensive effect of 1-Sar-8-Ala-angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354806"}
{"pmid": "4354805", "title": "In vivo changes in the concentration of cerebral cyclic AMP, phosphorylase a and glycogen induced by biogenic amines.", "content": "In vivo changes in the concentration of cerebral cyclic AMP, phosphorylase a and glycogen induced by biogenic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354805"}
{"pmid": "4354807", "title": "Effect of propranolol and theophylline on renin release caused by furosemide in the cat.", "content": "Effect of propranolol and theophylline on renin release caused by furosemide in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354807"}
{"pmid": "4354808", "title": "Inhibition by SQ 20881 of vasopressor response to angiotensin I in conscious animals.", "content": "Inhibition by SQ 20881 of vasopressor response to angiotensin I in conscious animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354808"}
{"pmid": "4354809", "title": "The effects of theophylline and cyclic AMP on intestinal smooth muscle contractions.", "content": "The effects of theophylline and cyclic AMP on intestinal smooth muscle contractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354809"}
{"pmid": "4354811", "title": "Behaviour of enzymes at high concentration. Use of permeabilised cells in the study of enzyme activity and its regulation.", "content": "Behaviour of enzymes at high concentration. Use of permeabilised cells in the study of enzyme activity and its regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354811"}
{"pmid": "4354810", "title": "In vitro inhibition by synthetic phospholipids of pressor responses to renin.", "content": "In vitro inhibition by synthetic phospholipids of pressor responses to renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354810"}
{"pmid": "4354812", "title": "Stereochemistry of the hydrogen transfer to the coenzyme by octopine dehydrogenase.", "content": "Stereochemistry of the hydrogen transfer to the coenzyme by octopine dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354812"}
{"pmid": "4354813", "title": "Enzyme kinetic parameters of the fluorescent ATP analogue, 2-aminopurine triphosphate.", "content": "Enzyme kinetic parameters of the fluorescent ATP analogue, 2-aminopurine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354813"}
{"pmid": "4354814", "title": "Histone phosphorylation in the regenerating rat liver independent of diurnal rhythmicity.", "content": "Histone phosphorylation in the regenerating rat liver independent of diurnal rhythmicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354814"}
{"pmid": "4354815", "title": "Identification of 5-fluorocytidine in RNA from Escherichia coli grown in the presence of 5-fluorouracil.", "content": "Identification of 5-fluorocytidine in RNA from Escherichia coli grown in the presence of 5-fluorouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354815"}
{"pmid": "4354816", "title": "Phosphorylase phosphatase: molecular configuration and activity.", "content": "Phosphorylase phosphatase: molecular configuration and activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354816"}
{"pmid": "4354817", "title": "Effects of long-acting thyroid stimulator on the reorganization into follicles of isolated thyroid cells and on the binding of radioiodinated thyrotropin to reassociated cells.", "content": "Effects of long-acting thyroid stimulator on the reorganization into follicles of isolated thyroid cells and on the binding of radioiodinated thyrotropin to reassociated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354817"}
{"pmid": "4354818", "title": "The superoxide dismutase activity of human erythrocuprein.", "content": "The superoxide dismutase activity of human erythrocuprein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354818"}
{"pmid": "4354819", "title": "Glutathione reductase and glutathione peroxidase activities in hepatomous livers of rats treated with diethylnitrosamine.", "content": "Glutathione reductase and glutathione peroxidase activities in hepatomous livers of rats treated with diethylnitrosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354819"}
{"pmid": "4354820", "title": "Carbohydrate composition and sequence analysis of cell surface components by mass spectrometry. Characterization of the major monosialoganglioside of brain.", "content": "Carbohydrate composition and sequence analysis of cell surface components by mass spectrometry. Characterization of the major monosialoganglioside of brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354820"}
{"pmid": "4354821", "title": "Cytochrome c linked nicotinic acid hydroxylase in Pseudomonas ovalis Chester.", "content": "Cytochrome c linked nicotinic acid hydroxylase in Pseudomonas ovalis Chester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354821"}
{"pmid": "4354822", "title": "Estrogen receptor: loss of DNA binding ability following trypsin or Ca2+ treatment.", "content": "Estrogen receptor: loss of DNA binding ability following trypsin or Ca2+ treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354822"}
{"pmid": "4354823", "title": "Preparation of antisera to alpha-fetoprotein making use of estradiol affinity column.", "content": "Preparation of antisera to alpha-fetoprotein making use of estradiol affinity column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354823"}
{"pmid": "4354825", "title": "Electron microscopic examination of hepatic subcellular fractions for phosphatases.", "content": "Electron microscopic examination of hepatic subcellular fractions for phosphatases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354825"}
{"pmid": "4354826", "title": "The production of IgE and IgG1 antibodies in guinea-pigs immunized with antigen and bacterial lipopolysaccharides.", "content": "The production of IgE and IgG1 antibodies in guinea-pigs immunized with antigen and bacterial lipopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354826"}
{"pmid": "4354827", "title": "Stimulation of transplantation immunity and plasma cell reaction by interferon in mice.", "content": "Stimulation of transplantation immunity and plasma cell reaction by interferon in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354827"}
{"pmid": "4354829", "title": "The redox behavior of metallo octaethylporphyrins.", "content": "The redox behavior of metallo octaethylporphyrins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354829"}
{"pmid": "4354828", "title": "Guinea-pig reaginic antibody. II. Physicochemical and biological properties.", "content": "Guinea-pig reaginic antibody. II. Physicochemical and biological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354828"}
{"pmid": "4354831", "title": "Structures of analogs of nicotinamide-adenine dinucleotide. II. Crystal structure of N-(3-(Aden-9-yl) propyl)-3-carbamoylpyridinium bromide hydrobromide dihydrate, (AdeH plus-C3-Nic+)2Br-2H2O.", "content": "Structures of analogs of nicotinamide-adenine dinucleotide. II. Crystal structure of N-(3-(Aden-9-yl) propyl)-3-carbamoylpyridinium bromide hydrobromide dihydrate, (AdeH plus-C3-Nic+)2Br-2H2O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354831"}
{"pmid": "4354830", "title": "Structure of analogs of nicotinamide-adenine dinucleotide. I. Crystal structure of N-(3-(aden-9-yl)propyl)-3-carbamoylpyridinium bromide trihydrate, (Ade-C3-Nic+)Br-3H2O.", "content": "Structure of analogs of nicotinamide-adenine dinucleotide. I. Crystal structure of N-(3-(aden-9-yl)propyl)-3-carbamoylpyridinium bromide trihydrate, (Ade-C3-Nic+)Br-3H2O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354830"}
{"pmid": "4354832", "title": "Structures of analogs of nicotinamide-adenine dinucleotide. 3. Crystal structure of 1,1'-trimethylenebisnicotinamide dichloride monohydrate, (Nic plus-C3-Nic+)2CL-H2O.", "content": "Structures of analogs of nicotinamide-adenine dinucleotide. 3. Crystal structure of 1,1'-trimethylenebisnicotinamide dichloride monohydrate, (Nic plus-C3-Nic+)2CL-H2O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354832"}
{"pmid": "4354833", "title": "Chemical evolution of a nitrogenase model. VI. The reduction of CN-, N3-, N2O, N2, and other substrates by molybdocysteine catalysts in the presence of nucleoside phosphates.", "content": "Chemical evolution of a nitrogenase model. VI. The reduction of CN-, N3-, N2O, N2, and other substrates by molybdocysteine catalysts in the presence of nucleoside phosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354833"}
{"pmid": "4354834", "title": "Transmethylation from toxoflavines to nucleophiles.", "content": "Transmethylation from toxoflavines to nucleophiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354834"}
{"pmid": "4354835", "title": "Rotamer stability of histidine and histidine derivatives.", "content": "Rotamer stability of histidine and histidine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354835"}
{"pmid": "4354836", "title": "Spectral characteristics of yeast cytochrome c's at the temperature of liquid nitrogen.", "content": "Spectral characteristics of yeast cytochrome c's at the temperature of liquid nitrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354836"}
{"pmid": "4354837", "title": "Carboxamidomethylation of yeast inorganic pyrophosphatase.", "content": "Carboxamidomethylation of yeast inorganic pyrophosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354837"}
{"pmid": "4354838", "title": "Effect of carboxyl group modification on some of the enzymatic properties of L-glutamate dehydrogenase.", "content": "Effect of carboxyl group modification on some of the enzymatic properties of L-glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354838"}
{"pmid": "4354839", "title": "High-pressure liquid chromatography of modified purine mononucleotides and nucleosides.", "content": "High-pressure liquid chromatography of modified purine mononucleotides and nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354839"}
{"pmid": "4354840", "title": "The analysis of estrogenic steroids in urine by high-speed liquid chromatography.", "content": "The analysis of estrogenic steroids in urine by high-speed liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354840"}
{"pmid": "4354841", "title": "Odontogenic myxoma: ultrastructural and histochemical studies.", "content": "Odontogenic myxoma: ultrastructural and histochemical studies. An odontogenic myxoma of a maxilla has been examined. Histochemistry of the mucosubstance indicated that hyaluronic acid and chondroitin sulphate were present. On ultrastructural examination many of the cells in the myxomatous tissue were seen with prominent rough endoplasmic reticulum, suggesting a secretory function, and possibly the myxomatous ground substance was produced by these cells. Cells containing collagen fibrils were found. Epithelial islands with intercellular spaces producing an arrangement similar to the stellate reticulum of the enamel organ were found, and possibly had developed from odontogenic epithelial rests. These islands were surrounded by a clear zone, outside which were cells with an increased prominence of adenosine-triphosphatase, nucleoside-diphosphatase, thiamine-pyrophosphatase, and often arylamidase reaction products. This probably represents a reaction of the mesodermal tissue to the epithelial islands. Possibly the epithelium exerts an inductive effect on the mesodermal tissue, and the myxomatous appearance may be the result of an aberrant development of mesodermal cells into ;myxoblasts' which secrete the myxomatous ground substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354841"}
{"pmid": "4354842", "title": "Phospholipids and their metabolism.", "content": "Phospholipids and their metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354842"}
{"pmid": "4354843", "title": "Lipid methodology.", "content": "Lipid methodology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354843"}
{"pmid": "4354844", "title": "Cholesterol metabolism.", "content": "Cholesterol metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354844"}
{"pmid": "4354845", "title": "Classification of lipoproteins and lipoprotein disorders.", "content": "Classification of lipoproteins and lipoprotein disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354845"}
{"pmid": "4354846", "title": "Lipoprotein fractionation.", "content": "Lipoprotein fractionation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354846"}
{"pmid": "4354847", "title": "Plasma triglyceride metabolism.", "content": "Plasma triglyceride metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354847"}
{"pmid": "4354848", "title": "Benzyl 6-oxopenicillanate and derivatives. II.", "content": "Benzyl 6-oxopenicillanate and derivatives. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354848"}
{"pmid": "4354851", "title": "Electron carriers of cytochrome oxidase detectable by electron paramagnetic resonance and their relationship to those traditionally recognized in this enzyme.", "content": "Electron carriers of cytochrome oxidase detectable by electron paramagnetic resonance and their relationship to those traditionally recognized in this enzyme. On the basis of oxidoreductive rapid kinetic and titration experiments with purified cytochrome c oxidase (EC 1.9.3.1), monitored by electron paramagnetic resonance (EPR) at 13 degrees K and by spectrophotometry at 100 degrees K, a new assignment of EPR signals is proposed. The bulk of both the low-spin (g = 3.0; 2.2; 1.5) and highspin (g = 6; 2) signals is attributed to the component with the properties of traditional cytochrome a. It is further proposed that the absorption band at 655 nm represents the most unambiguous manifestation of the a(3) component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354851"}
{"pmid": "4354853", "title": "Independent segregation of the H-2 locus and the locus for responsiveness to histamine-sensitizing factor.", "content": "Independent segregation of the H-2 locus and the locus for responsiveness to histamine-sensitizing factor. The inheritance of responsiveness to histamine-sensitizing factor of pertussis bacilli was examined in (SWR/J x CBA/J)F(1) x CBA/J backcross mice. We found that about half of the backcross mice inherited this responsiveness in both sexes. There was no linkage between the inheritance of responsiveness to histamine-sensitizing factor and the H-2(q) locus from the sensitive SW/J progenitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354853"}
{"pmid": "4354852", "title": "Malignant lymphoma in cottontop marmosets after inoculation with Epstein-Barr virus.", "content": "Malignant lymphoma in cottontop marmosets after inoculation with Epstein-Barr virus. Neoplasia resembling human malignant lymphoma, reticulum cell sarcoma type, occurred in cottontop marmosets inoculated with materials containing Epstein-Barr virus. One of four monkeys that received autologous cells transformed in vitro by Epstein-Barr virus developed lymphoma in mesenteric lymph nodes 7.5 months after inoculation. Three of four marmosets inoculated with cell-free Epstein-Barr virus developed lymphoma. The latent period for detectable tumor formation after addition of virus was 31-46 days. Immunosuppressive drugs given with the virus accelerated the course of disease. Nevertheless, malignant lymphoma occurred in an animal given only cell-free virus. Six of eight marmosets inoculated with the virus demonstrated antibodies to the virus. Four marmosets not exposed to the virus, including two that received immunosuppressive drugs, developed neither tumors nor antibodies to Epstein-Barr virus. Virus antigen detectable by immunofluorescence was found in 5% of cells shed from one tumor maintained in organ culture. These results imply that Epstein-Barr virus is capable of inducing malignant lymphoma in at least one primate species. Additional evidence is required before its oncogenic capacity in this host can be accepted without reservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354852"}
{"pmid": "4354854", "title": "Cyclic adenosine monophosphate receptor: loss of cAMP-dependent DNA binding activity after proteolysis in the presence of cyclic adenosine monophosphate.", "content": "Cyclic adenosine monophosphate receptor: loss of cAMP-dependent DNA binding activity after proteolysis in the presence of cyclic adenosine monophosphate. The cAMP receptor requires cAMP for DNA binding at pH 8.0 but shows cAMP-independent DNA binding at pH 6.0. Incubation of the cAMP receptor with proteolytic enzymes in the presence of cAMP results in loss of DNA-binding ability at pH 8, while it is still able to bind cAMP and DNA at pH 6. Incubation with proteolytic enzyme in the absence of cAMP does not affect the DNA-binding properties of the cAMP receptor. After proteolysis in the presence of cAMP, analysis by sodium dodecyl sulfateacrylamide-gel electrophoresis shows that the 22,500-dalton subunit characteristic of the untreated protein has been completely replaced by a 12,500-dalton fragment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354854"}
{"pmid": "4354855", "title": "An immobilized three-enzyme system: a model for microenvironmental compartmentation in mitochondria.", "content": "An immobilized three-enzyme system: a model for microenvironmental compartmentation in mitochondria. An immobilized three-enzyme system, malate dehydrogenase (EC 1.1.1.37)-citrate synthase (EC 4.1.3.7)-lactate dehydrogenase (EC 1.1.1.27), was investigated as a model for the rate of oxalacetate production and utilization in mitochondria. Lactate dehydrogenase is included to mimic the NADH-utilizing system of mitochondria. This three-enzyme system was immobilized in three different ways (1) on Sephadex G-50 (surface coupling), (2) on Sepharose 4B (internal-external coupling), and (3) entrapped in polycrylamide gel. The rate of citrate production from malate, NAD(+), and acetyl CoA was determined continuously in a flow system. Up to about 100% rate enhancements were observed when the immobilized system was compared to identical systems of free enzyme. An even more pronounced increase of rate of up to about 400% compared to the soluble system was measured after addition of pyruvate (to reoxidize formed NADH). These results are interpreted in relation to microenvironmental changes of oxalacetate production and the possible organization of enzymes of the Krebs cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354855"}
{"pmid": "4354856", "title": "Host restriction of Friend leukemia virus. Role of the viral outer coat.", "content": "Host restriction of Friend leukemia virus. Role of the viral outer coat. Host restriction of oncogenesis of RNA tumor viruses in vivo is associated with several gene loci. One of these genes, the Fv-1 locus in mice, is expressed in vitro and may be studied in mouse-embryo cultures that are restrictive or permissive for replication of Friend leukemia virus. Two strains of Friend leukemia virus, N-or B-tropic, show reciprocal ability to replicate successfully in either NIH Swiss (N-type) or BALB/c (B-type) cells that differ at the Fv-1 locus. These two strains of virus and two cell lines form a system to measure host restriction in vitro. Measurement of adsorption of Friend leukemia virus to permissive or restrictive cells reveals no difference in rate or total amount of virus bound. Furthermore, studies with virions of vesicular stomatitis virus phenotypically mixed within an envelope containing Friend leukemia virus protein show no differences in penetration or replication of vesicular stomatitis virus. These results strongly suggest that host restriction of Friend leukemia virus is due to an intracellular event in the viral replication cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354856"}
{"pmid": "4354857", "title": "Reexpression of the rat hypoxanthine phosphoribosyltransferase gene in rat-human hybrids.", "content": "Reexpression of the rat hypoxanthine phosphoribosyltransferase gene in rat-human hybrids. Fusion of hypoxanthine phosphoribosyltransferase (HPRT)(-) rat hepatoma cells with HPRT(+) human fibroblasts yielded hybrid clones that grew in HAT selective medium and contained all the rat chromosomes and one to nine human chromosomes. Among the retained chromosomes was the human X chromosome. In all clones backselected in medium containing 8-azaguanine, human X chromosome was absent. Electrophoretic analysis revealed that, without exception, hybrid clones growing in HAT medium had an active HPRT enzyme, either human or rat, or both. When these clones were backselected in 8-azaguanine, they did not show HPRT enzyme activity. Hybrids that contained the human X chromosome also had human glucose-6-phosphate dehydrogenase. The observed reexpression of rat HPRT in hybrid cells derived from HPRT(-) rat cells suggests that a genetic factor from the human cell determined the expression of the rat structural gene for HPRT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354857"}
{"pmid": "4354858", "title": "Replacement of the sequence G-T-phi-C-G(A)- by G-A-U-C-G- in initiator transfer RNA of rabbit-liver cytoplasm.", "content": "Replacement of the sequence G-T-phi-C-G(A)- by G-A-U-C-G- in initiator transfer RNA of rabbit-liver cytoplasm. Eukaryotic cytoplasmic initiator tRNAs lack the sequence G-T-Psi-C-G(A)-, which is in every tRNA of known sequence that is active in protein biosynthesis. In initiator tRNA of yeast cytoplasm, which is the only eukaryotic initiator tRNA of known sequence, this sequence is replaced by G-A-U-C-G-. We now report the sequence of a 30-nucleotide-long, 3'-terminal fragment of cytoplasmic initiator tRNA of rabbit liver obtained by specific cleavage of the tRNA at the site occupied by the modified nucleoside, 7-methyl guanosine. We show (i) that in rabbit-liver initiator tRNA also, the sequence G-T-Psi-C-G(A)- is replaced by G-A-U-C-G- and (ii) that the sequences of loop IV of both the yeast and rabbit-liver cytoplasmic initiator tRNAs are identical, A-U-C-G-m(1)-A-A-A-.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354858"}
{"pmid": "4354860", "title": "Pituitary extracts and steroid hormones in the control of 3T3 cell growth.", "content": "Pituitary extracts and steroid hormones in the control of 3T3 cell growth. Results are reported showing that pituitary extracts stimulate growth of 3T3 cells, an established line of mouse fibroblast. Cells were cultured in medium containing an organic buffer (HEPES; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid), which increases the serum requirement for cell growth. The pituitary growth-prompting activity is (a) not dialyzable; (b) thermolabile; (c) protease sensitive; and (d) enhanced by hydrocortisone (a steroid hormone). Activity was quantitatively assayed by measurement of stimulation of cell division or [(3)H]thymidine uptake into DNA. The active species is probably different from pituitary protein hormones and it seems to be effective at concentrations observed for protein hormones in vivo. 3T3 cells transformed by simian virus 40 are not responsive to this activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354860"}
{"pmid": "4354859", "title": "Enzyme loading of erythrocytes.", "content": "Enzyme loading of erythrocytes. We demonstrated that beta-glucosidase and beta-galactosidase can be trapped inside erythrocytes by rapid hemolysis of the cell in the presence of these enzymes. Enzyme enters only during hemolysis, and optimum uptake occurs within 60 sec. There is no loss in cell number after hemolysis-induced enzyme uptake, and the ghosts have only a slightly increased mean cell volume. Smaller proteins enter more readily than larger proteins, although enzymes with a molecular weight of at least 180,000 can be readily entrapped by erythrocytes. This finding may provide a useful approach to the problem of enzyme replacement in certain diseases, including Gaucher's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354859"}
{"pmid": "4354862", "title": "Toward a comparative biochemistry of the cytochromes.", "content": "Toward a comparative biochemistry of the cytochromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354862"}
{"pmid": "4354864", "title": "Production of hemorrhagic necrosis in guinea pigs with anti-streptococcal antisera.", "content": "Production of hemorrhagic necrosis in guinea pigs with anti-streptococcal antisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354864"}
{"pmid": "4354865", "title": "Non-specific arthralgia and myalgia with subclinical neuropathy. A histochemical and histological study.", "content": "Non-specific arthralgia and myalgia with subclinical neuropathy. A histochemical and histological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354865"}
{"pmid": "4354866", "title": "Selective secretion of lysosomal enzymes of the Yoshida hepatoma AH 130 in the peritoneal fluid.", "content": "Selective secretion of lysosomal enzymes of the Yoshida hepatoma AH 130 in the peritoneal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354866"}
{"pmid": "4354867", "title": "Calcium binding to phospholipids from experimental tumors.", "content": "Calcium binding to phospholipids from experimental tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354867"}
{"pmid": "4354868", "title": "Pseudomonas cytochrome c peroxidase. IX. Molecular weight of the enzyme in dodecyl sulfate-polyacrylamide gel electrophoresis.", "content": "Pseudomonas cytochrome c peroxidase. IX. Molecular weight of the enzyme in dodecyl sulfate-polyacrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354868"}
{"pmid": "4354869", "title": "Calcification in adenocarcinoma.", "content": "Calcification in adenocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354869"}
{"pmid": "4354870", "title": "Ultrastructure of the obligately anaerobic bacteria Clostridium kluyveri and Cl. acetobutylicum.", "content": "Ultrastructure of the obligately anaerobic bacteria Clostridium kluyveri and Cl. acetobutylicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354870"}
{"pmid": "4354871", "title": "Acute effects of actinomycin D on the binding of tritiated oestradiol by the mouse vagina.", "content": "Acute effects of actinomycin D on the binding of tritiated oestradiol by the mouse vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354871"}
{"pmid": "4354872", "title": "The membrane ATPase of Escherichia coli. I. Release into solution, allotopic properties and reconstitution of membrane-bound ATPase.", "content": "The membrane ATPase of Escherichia coli. I. Release into solution, allotopic properties and reconstitution of membrane-bound ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354872"}
{"pmid": "4354873", "title": "Polycation inhibition of chloroplast photosystem I.", "content": "Polycation inhibition of chloroplast photosystem I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354873"}
{"pmid": "4354875", "title": "Nitrogenase. IV. Simple method of purification to homogeneity of nitrogenase components from Azotobacter vinelandii.", "content": "Nitrogenase. IV. Simple method of purification to homogeneity of nitrogenase components from Azotobacter vinelandii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354875"}
{"pmid": "4354874", "title": "On the triple localization of creatine kinase in heart and skeletal muscle cells of the rat: evidence for the existence of myofibrillar and mitochondrial isoenzymes.", "content": "On the triple localization of creatine kinase in heart and skeletal muscle cells of the rat: evidence for the existence of myofibrillar and mitochondrial isoenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354874"}
{"pmid": "4354876", "title": "Acylation of Escherichia coli tRNAtrp with 5-methyltryptophan by E. coli tryptophanyl-tRNA ligase.", "content": "Acylation of Escherichia coli tRNAtrp with 5-methyltryptophan by E. coli tryptophanyl-tRNA ligase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354876"}
{"pmid": "4354877", "title": "Regulation of RNA synthesis in Escherichia coli. I. Characterization of cells subjected to simultaneous temperature and osmotic shock.", "content": "Regulation of RNA synthesis in Escherichia coli. I. Characterization of cells subjected to simultaneous temperature and osmotic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354877"}
{"pmid": "4354878", "title": "Evidence for de novo synthesis of collagenase by tadpole skin explant.", "content": "Evidence for de novo synthesis of collagenase by tadpole skin explant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354878"}
{"pmid": "4354879", "title": "Superficial hydradenoma of the cheek.", "content": "Superficial hydradenoma of the cheek.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354879"}
{"pmid": "4354880", "title": "Activity of adenosine 3',5'-cyclic monophosphate phosphodiesterase in tissues of adult locust Schistocerca gregaria L. (Orthoptera).", "content": "Activity of adenosine 3',5'-cyclic monophosphate phosphodiesterase in tissues of adult locust Schistocerca gregaria L. (Orthoptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354880"}
{"pmid": "4354881", "title": "The lipid core model of lipoproteins.", "content": "The lipid core model of lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354881"}
{"pmid": "4354884", "title": "Effect of aldosterone on cyclic-AMP metabolism in the urinary bladder of the toad.", "content": "Effect of aldosterone on cyclic-AMP metabolism in the urinary bladder of the toad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354884"}
{"pmid": "4354885", "title": "Cyclic-AMP in the aqueous humor: the effects of repeated topical epinephrine administration and sympathetic denervation.", "content": "Cyclic-AMP in the aqueous humor: the effects of repeated topical epinephrine administration and sympathetic denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354885"}
{"pmid": "4354886", "title": "Cyclic nucleotides and photoreception.", "content": "Cyclic nucleotides and photoreception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354886"}
{"pmid": "4354889", "title": "Cytotoxic compounds. XVI. Reactions of the bismethanesulphonates of 3-(N-methylanilino)propane-1,2-diol and of 2-(N-methylanilino)-propane-1,3-diol with nucleophiles.", "content": "Cytotoxic compounds. XVI. Reactions of the bismethanesulphonates of 3-(N-methylanilino)propane-1,2-diol and of 2-(N-methylanilino)-propane-1,3-diol with nucleophiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354889"}
{"pmid": "4354890", "title": "Isoindole.", "content": "Isoindole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354890"}
{"pmid": "4354891", "title": "Sizes of end plate compartments, densities of acetylcholine receptor and other quantitative aspects of neuromuscular transmission.", "content": "Sizes of end plate compartments, densities of acetylcholine receptor and other quantitative aspects of neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354891"}
{"pmid": "4354892", "title": "Cellular events in tolerance. I. Failure to demonstrate activation of lymphocytes, blocking factors, or suppressor cells during the induction of tolerance to a soluble protein.", "content": "Cellular events in tolerance. I. Failure to demonstrate activation of lymphocytes, blocking factors, or suppressor cells during the induction of tolerance to a soluble protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354892"}
{"pmid": "4354893", "title": "Histological and ultrastructural changes in the blastocyst and reproductive tract of the roe deer, Capreolus capreolus, during delayed implantation.", "content": "Histological and ultrastructural changes in the blastocyst and reproductive tract of the roe deer, Capreolus capreolus, during delayed implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354893"}
{"pmid": "4354894", "title": "A re-examination of the rôle of phospholipids as energy substrates during incubation of ram spermatozoa.", "content": "A re-examination of the rôle of phospholipids as energy substrates during incubation of ram spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354894"}
{"pmid": "4354900", "title": "Hormone receptors.", "content": "Hormone receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354900"}
{"pmid": "4354901", "title": "A mutant of Escherichia coli K12 deficient in the 5'-3' exonucleolytic activity of DNA polymerase I. I. General characterization.", "content": "A mutant of Escherichia coli K12 deficient in the 5'-3' exonucleolytic activity of DNA polymerase I. I. General characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354901"}
{"pmid": "4354903", "title": "Pollicization for congenital deformities of the hand.", "content": "Pollicization for congenital deformities of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354903"}
{"pmid": "4354904", "title": "Associated carcinomata of colon and anus.", "content": "Associated carcinomata of colon and anus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354904"}
{"pmid": "4354911", "title": "Radiographic appearance of bronchial carcinoid.", "content": "Radiographic appearance of bronchial carcinoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354911"}
{"pmid": "4354916", "title": "Calcitonin- and ACTH-producing cells in a case of medullary carcinoma of the thyroid. Immunofluorescence investigations.", "content": "Calcitonin- and ACTH-producing cells in a case of medullary carcinoma of the thyroid. Immunofluorescence investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354916"}
{"pmid": "4354918", "title": "Liver necrosis, adenovirus type 2 and thymic dysplasia.", "content": "Liver necrosis, adenovirus type 2 and thymic dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354918"}
{"pmid": "4354920", "title": "RNAs as amplifiers of specific signals in immunity.", "content": "RNAs as amplifiers of specific signals in immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354920"}
{"pmid": "4354921", "title": "Various enzymes involved with putative neurotransmitters. Regional distribution in the brain of deceased mentally normal, chronic schizophrenics or organic brain syndrome patients.", "content": "Various enzymes involved with putative neurotransmitters. Regional distribution in the brain of deceased mentally normal, chronic schizophrenics or organic brain syndrome patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354921"}
{"pmid": "4354923", "title": "Electron microscopy of selectively stimulated microconidiogenesis in wild type Neurospora crassa.", "content": "Electron microscopy of selectively stimulated microconidiogenesis in wild type Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354923"}
{"pmid": "4354924", "title": "Structure and plugging of septa of wild type and spreading colonial mutants of Neurospora crassa.", "content": "Structure and plugging of septa of wild type and spreading colonial mutants of Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354924"}
{"pmid": "4354925", "title": "The regulation of liver glycogen synthetase D phosphatase by ATP and glucose.", "content": "The regulation of liver glycogen synthetase D phosphatase by ATP and glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354925"}
{"pmid": "4354927", "title": "A preliminary immunochemical study of E. coli aspartokinase I-homoserine dehydrogenase I.", "content": "A preliminary immunochemical study of E. coli aspartokinase I-homoserine dehydrogenase I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354927"}
{"pmid": "4354926", "title": "Modification of polynucleotides by a fragment produced by enzymatic cleavage of S-(1, 2-dichlorovinyl)-L-cysteine.", "content": "Modification of polynucleotides by a fragment produced by enzymatic cleavage of S-(1, 2-dichlorovinyl)-L-cysteine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354926"}
{"pmid": "4354929", "title": "Subunits of oncornavirus high-molecular-weight RNA. I. Stepwise conversion of 60 S AMV (avian myeloblastosis virus) RNA to subunits.", "content": "Subunits of oncornavirus high-molecular-weight RNA. I. Stepwise conversion of 60 S AMV (avian myeloblastosis virus) RNA to subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354929"}
{"pmid": "4354928", "title": "Binding of progesterone by rat uterus in vitro.", "content": "Binding of progesterone by rat uterus in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354928"}
{"pmid": "4354930", "title": "Low temperature electron paramagnetic resonance studies on two iron-sulfur centers in cardiac succinate dehydrogenase.", "content": "Low temperature electron paramagnetic resonance studies on two iron-sulfur centers in cardiac succinate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354930"}
{"pmid": "4354931", "title": "13C nuclear magnetic resonance studies of the conformation of the X-pro bond in the oligopeptide hormones, thyrotropin-releasing hormone, luteinizing hormone-releasing factor, angiotensin and melanocyte-stimulating hormone release-inhibiting factor.", "content": "13C nuclear magnetic resonance studies of the conformation of the X-pro bond in the oligopeptide hormones, thyrotropin-releasing hormone, luteinizing hormone-releasing factor, angiotensin and melanocyte-stimulating hormone release-inhibiting factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354931"}
{"pmid": "4354932", "title": "Alanine formation by rat muscle homogenate.", "content": "Alanine formation by rat muscle homogenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354932"}
{"pmid": "4354933", "title": "Alternate pathways of D-fructose transport and metabolism in Arthrobacter pyridinolis.", "content": "Alternate pathways of D-fructose transport and metabolism in Arthrobacter pyridinolis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354933"}
{"pmid": "4354934", "title": "Adenosine 3', 5'-monophosphate-dependent protein kinase in adipose tissue: inhibition by tolbutamide.", "content": "Adenosine 3', 5'-monophosphate-dependent protein kinase in adipose tissue: inhibition by tolbutamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354934"}
{"pmid": "4354935", "title": "Conversion of DNA polymerase extracted from rat ascites hepatoma cells.", "content": "Conversion of DNA polymerase extracted from rat ascites hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354935"}
{"pmid": "4354937", "title": "Adenosine 3',5' monophosphate binds only to the inner surface of human erythrocyte membranes.", "content": "Adenosine 3',5' monophosphate binds only to the inner surface of human erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354937"}
{"pmid": "4354936", "title": "Effect of cytochalasin B on lymphocyte stimulation induced by concanavalin A or periodate.", "content": "Effect of cytochalasin B on lymphocyte stimulation induced by concanavalin A or periodate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354936"}
{"pmid": "4354938", "title": "A spin-label for RNA study.", "content": "A spin-label for RNA study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354938"}
{"pmid": "4354939", "title": "Binding of thyrotropin releasing hormone by thyrotropin-secreting cells.", "content": "Binding of thyrotropin releasing hormone by thyrotropin-secreting cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354939"}
{"pmid": "4354940", "title": "The molecular weight of NADPH-cytochrome C reductase isolated by immunoprecipitation from detergent-solubilized rat liver microsomes.", "content": "The molecular weight of NADPH-cytochrome C reductase isolated by immunoprecipitation from detergent-solubilized rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354940"}
{"pmid": "4354941", "title": "Gluconate metabolism in Pseudomonas: a novel pathway of glyceraldehyde-3-phosphate metabolism.", "content": "Gluconate metabolism in Pseudomonas: a novel pathway of glyceraldehyde-3-phosphate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354941"}
{"pmid": "4354942", "title": "Cyclic nucleotide-dependent protein kinases of the rat pancreas.", "content": "Cyclic nucleotide-dependent protein kinases of the rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354942"}
{"pmid": "4354943", "title": "Control of calcium absorption and intestinal calcium-binding protein synthesis.", "content": "Control of calcium absorption and intestinal calcium-binding protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354943"}
{"pmid": "4354944", "title": "Studies on ATP-dependent deoxyribonuclease of Haemophilus influenzae: involvement of the enzyme in the transformation process.", "content": "Studies on ATP-dependent deoxyribonuclease of Haemophilus influenzae: involvement of the enzyme in the transformation process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354944"}
{"pmid": "4354945", "title": "Synthesis in vitro of vesicular stomatitis virus proteins in cytoplasmic extracts of L cells.", "content": "Synthesis in vitro of vesicular stomatitis virus proteins in cytoplasmic extracts of L cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354945"}
{"pmid": "4354946", "title": "Protein kinase activity in Morris hepatomas.", "content": "Protein kinase activity in Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354946"}
{"pmid": "4354947", "title": "Role of 3',5'-cyclic AMP in the control of nuclear protein kinase activity.", "content": "Role of 3',5'-cyclic AMP in the control of nuclear protein kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354947"}
{"pmid": "4354948", "title": "Endonuclease of high specific activity in a purified mouse interferon preparation.", "content": "Endonuclease of high specific activity in a purified mouse interferon preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354948"}
{"pmid": "4354949", "title": "The stability of collagen cross-links when derived from hydroxylsyl residues.", "content": "The stability of collagen cross-links when derived from hydroxylsyl residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354949"}
{"pmid": "4354950", "title": "Effect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat hypothalamus.", "content": "Effect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354950"}
{"pmid": "4354951", "title": "Formation of retinol (alpha, beta-32P) pyrophosphate with (gamma-32P) ATP catalysed by whole homogenates of rat thyroid.", "content": "Formation of retinol (alpha, beta-32P) pyrophosphate with (gamma-32P) ATP catalysed by whole homogenates of rat thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354951"}
{"pmid": "4354952", "title": "An iron tetrahydroporphyrin prosthetic group common to both assimilatory and dissimilatory sulfite reductases.", "content": "An iron tetrahydroporphyrin prosthetic group common to both assimilatory and dissimilatory sulfite reductases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354952"}
{"pmid": "4354953", "title": "Similar and opposite effects of dibutyryl cyclic AMP and insulin on glucose metabolism in adipose tissue.", "content": "Similar and opposite effects of dibutyryl cyclic AMP and insulin on glucose metabolism in adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354953"}
{"pmid": "4354954", "title": "Effects of thyrotropin, prostaglandin E1 and iodide on cyclic 3',5'-AMP concentration in dog thyroid slices.", "content": "Effects of thyrotropin, prostaglandin E1 and iodide on cyclic 3',5'-AMP concentration in dog thyroid slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354954"}
{"pmid": "4354955", "title": "Development of cyclic AMP metabolism in rat liver. A correlative study of tissue levels of cyclic AMP, accumulation of cyclic AMP in slices, adenylate cyclase activity and cyclic nucleotide phosphodiesterase activity.", "content": "Development of cyclic AMP metabolism in rat liver. A correlative study of tissue levels of cyclic AMP, accumulation of cyclic AMP in slices, adenylate cyclase activity and cyclic nucleotide phosphodiesterase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354955"}
{"pmid": "4354956", "title": "The role of calcium in the steroidogenic response of rat adrenal cells to adrenocorticotropic hormone.", "content": "The role of calcium in the steroidogenic response of rat adrenal cells to adrenocorticotropic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354956"}
{"pmid": "4354957", "title": "Gonadotropin receptors in the plasma membranes of rat luteal cells.", "content": "Gonadotropin receptors in the plasma membranes of rat luteal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354957"}
{"pmid": "4354961", "title": "Enzyme cytochemical observations on the tissue stages of the life cycle of Eimeria acervulina and Eimeria necatrix.", "content": "Enzyme cytochemical observations on the tissue stages of the life cycle of Eimeria acervulina and Eimeria necatrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354961"}
{"pmid": "4354962", "title": "Changes in oxidative metabolism and ultrastructure accompanying differentiation of the mitochondrion in Trypanosoma brucei.", "content": "Changes in oxidative metabolism and ultrastructure accompanying differentiation of the mitochondrion in Trypanosoma brucei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354962"}
{"pmid": "4354964", "title": "Oat cell carcinoma of the trachea.", "content": "Oat cell carcinoma of the trachea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354964"}
{"pmid": "4354963", "title": "Paracrystalline arrays in mitochondria following ageing of mitochondria in situ.", "content": "Paracrystalline arrays in mitochondria following ageing of mitochondria in situ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354963"}
{"pmid": "4354966", "title": "Effect of the local administration of proteolytic enzymes on the rupture of the ovarian follicle in the domestic fowl, Gallus domesticus.", "content": "Effect of the local administration of proteolytic enzymes on the rupture of the ovarian follicle in the domestic fowl, Gallus domesticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354966"}
{"pmid": "4354968", "title": "Phospholipid composition of bovine sperm fractions, seminal plasma and cytoplasmic droplets.", "content": "Phospholipid composition of bovine sperm fractions, seminal plasma and cytoplasmic droplets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354968"}
{"pmid": "4354969", "title": "Effect of morphine administration on adenyl cyclase and 3',5'-cyclic nucleotide phosphodiesterase activities in the brain.", "content": "Effect of morphine administration on adenyl cyclase and 3',5'-cyclic nucleotide phosphodiesterase activities in the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354969"}
{"pmid": "4354967", "title": "Metabolism of fatty acids by ovine spermatozoa.", "content": "Metabolism of fatty acids by ovine spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354967"}
{"pmid": "4354970", "title": "Modification of Baird-Parker's classification system of Staphylococcus albus.", "content": "Modification of Baird-Parker's classification system of Staphylococcus albus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354970"}
{"pmid": "4354972", "title": "The detection of different progenies induced by fractionated infectious poliovirus RNA.", "content": "The detection of different progenies induced by fractionated infectious poliovirus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354972"}
{"pmid": "4354971", "title": "Latent infection of monkeys with oncogenic herpes viruses.", "content": "Latent infection of monkeys with oncogenic herpes viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354971"}
{"pmid": "4354973", "title": "Simple preparation of 3H-labelled poliovirus for chromatographic strain differentiation with aluminium hydroxide and one-year control of labelled reference strains.", "content": "Simple preparation of 3H-labelled poliovirus for chromatographic strain differentiation with aluminium hydroxide and one-year control of labelled reference strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354973"}
{"pmid": "4354974", "title": "The role of lysosomes in virus-induced cell fusion. 2. Modification of the cell surface.", "content": "The role of lysosomes in virus-induced cell fusion. 2. Modification of the cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354974"}
{"pmid": "4354975", "title": "The role of lysosomes in virus-induced cell fusion. 1. Cytochemical studies.", "content": "The role of lysosomes in virus-induced cell fusion. 1. Cytochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354975"}
{"pmid": "4354976", "title": "A study of the conformational properties of hemoglobin by the method of two paramagnetic labels.", "content": "A study of the conformational properties of hemoglobin by the method of two paramagnetic labels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354976"}
{"pmid": "4354990", "title": "Some properties of cortisol-receptor complex isolated from cytoplasm of rat liver and its effect on biosynthesis of nuclear RNA.", "content": "Some properties of cortisol-receptor complex isolated from cytoplasm of rat liver and its effect on biosynthesis of nuclear RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354990"}
{"pmid": "4354992", "title": "Demonstration of a specific binding protein for testosterone and 5alpha-dihydrotestosterone in rabbit serum. Separation from the corticosteroid binding globulin (CBG).", "content": "Demonstration of a specific binding protein for testosterone and 5alpha-dihydrotestosterone in rabbit serum. Separation from the corticosteroid binding globulin (CBG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354992"}
{"pmid": "4354991", "title": "In vitro effects of ACTH on uridine incorporation into rapidly labelled adrenal RNA of normal and dexamethasone-suppressed rats.", "content": "In vitro effects of ACTH on uridine incorporation into rapidly labelled adrenal RNA of normal and dexamethasone-suppressed rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354991"}
{"pmid": "4354993", "title": "Estrogen receptor protein of pancreas.", "content": "Estrogen receptor protein of pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354993"}
{"pmid": "4354998", "title": "Water soluble proteins from rat brain and from experimental tumors of rat nervous system.", "content": "Water soluble proteins from rat brain and from experimental tumors of rat nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4354998"}
{"pmid": "4355000", "title": "1-Nitroso-5, 6-dihydrouracil: induction of liver cell carcinomas and kidney adenomas in the rat.", "content": "1-Nitroso-5, 6-dihydrouracil: induction of liver cell carcinomas and kidney adenomas in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355000"}
{"pmid": "4355005", "title": "Epidemiology of respiratory syncytial virus infection in Washington, D.C. I. Importance of the virus in different respiratory tract disease syndromes and temporal distribution of infection.", "content": "Epidemiology of respiratory syncytial virus infection in Washington, D.C. I. Importance of the virus in different respiratory tract disease syndromes and temporal distribution of infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355005"}
{"pmid": "4355006", "title": "Adrenocortical function after major gastric surgery.", "content": "Adrenocortical function after major gastric surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355006"}
{"pmid": "4355007", "title": "Alteration in liver mitochondrial metabolism in a patient with biliary obstruction due to liver carcinoma.", "content": "Alteration in liver mitochondrial metabolism in a patient with biliary obstruction due to liver carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355007"}
{"pmid": "4355008", "title": "Granular cell myoblastoma of the breast.", "content": "Granular cell myoblastoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355008"}
{"pmid": "4355009", "title": "Pentamidine isothionate levels in lungs, livers, and kidneys of rats after aerosol or intramuscular administration.", "content": "Pentamidine isothionate levels in lungs, livers, and kidneys of rats after aerosol or intramuscular administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355009"}
{"pmid": "4355010", "title": "Bovine respiratory secretion as a two-phase system. Effect of parainfluenza-3 virus on the rheologic properties of the phases.", "content": "Bovine respiratory secretion as a two-phase system. Effect of parainfluenza-3 virus on the rheologic properties of the phases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355010"}
{"pmid": "4355012", "title": "Pulmonary blastoma.", "content": "Pulmonary blastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355012"}
{"pmid": "4355011", "title": "Persistent infection with parainfluenza type 3 virus in man.", "content": "Persistent infection with parainfluenza type 3 virus in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355011"}
{"pmid": "4355014", "title": "The mechanism of inhibition by fluoride of fatty acid oxidation in uncoupled mitochondria.", "content": "The mechanism of inhibition by fluoride of fatty acid oxidation in uncoupled mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355014"}
{"pmid": "4355013", "title": "Changes in the lipid and fatty acid composition of developing rabbit brain.", "content": "Changes in the lipid and fatty acid composition of developing rabbit brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355013"}
{"pmid": "4355015", "title": "Further characterization of fatty acyl monoester lipase from human adipose tissue.", "content": "Further characterization of fatty acyl monoester lipase from human adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355015"}
{"pmid": "4355016", "title": "Free and sulphate-conjugated 16-unsaturated C19 steroids in human testis tissue.", "content": "Free and sulphate-conjugated 16-unsaturated C19 steroids in human testis tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355016"}
{"pmid": "4355017", "title": "Tetrahydropteridine-dependent cleavage enzyme for O-alkyl lipids: substrate specificity.", "content": "Tetrahydropteridine-dependent cleavage enzyme for O-alkyl lipids: substrate specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355017"}
{"pmid": "4355019", "title": "5'-Nucleotide phosphodiesterase isoenzyme pattern in the serum of human hepatoma.", "content": "5'-Nucleotide phosphodiesterase isoenzyme pattern in the serum of human hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355019"}
{"pmid": "4355018", "title": "The acyl lipids of highly purified plant mitochondria.", "content": "The acyl lipids of highly purified plant mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355018"}
{"pmid": "4355020", "title": "Comparison of cell coat acid mucopolysaccharides of normal liver and various ascites hepatoma cells.", "content": "Comparison of cell coat acid mucopolysaccharides of normal liver and various ascites hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355020"}
{"pmid": "4355021", "title": "Guanosine anabolism for biosynthesis of nucleic acids in Novikoff ascites rat tumor cells in culture.", "content": "Guanosine anabolism for biosynthesis of nucleic acids in Novikoff ascites rat tumor cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355021"}
{"pmid": "4355022", "title": "The effect of pH on the morphology, electrophoretic mobility, and infectivity of the mouse mammary tumor virus.", "content": "The effect of pH on the morphology, electrophoretic mobility, and infectivity of the mouse mammary tumor virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355022"}
{"pmid": "4355023", "title": "Virus morphogenesis in a mouse lymphoma.", "content": "Virus morphogenesis in a mouse lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355023"}
{"pmid": "4355024", "title": "Effects of the antineoplastic alkaloid acronycine on the ultrastructure and growth patterns of cultured cells.", "content": "Effects of the antineoplastic alkaloid acronycine on the ultrastructure and growth patterns of cultured cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355024"}
{"pmid": "4355026", "title": "Tissue culture and animal studies with an oncolytic bovine enterovirus (bovine enterovirus 1).", "content": "Tissue culture and animal studies with an oncolytic bovine enterovirus (bovine enterovirus 1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355026"}
{"pmid": "4355025", "title": "Incorporation of 2-deoxy-D-glucose into glucoproteins of normal and Simian virus 40-transformed hamster cells.", "content": "Incorporation of 2-deoxy-D-glucose into glucoproteins of normal and Simian virus 40-transformed hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355025"}
{"pmid": "4355027", "title": "Purine nucleotide metabolism and nucleotide pool sizes in synchronized lymphoma L5178Y cells.", "content": "Purine nucleotide metabolism and nucleotide pool sizes in synchronized lymphoma L5178Y cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355027"}
{"pmid": "4355028", "title": "The protective effect of estradiol-17 beta against polycyclic hydrocarbon cytotoxicity.", "content": "The protective effect of estradiol-17 beta against polycyclic hydrocarbon cytotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355028"}
{"pmid": "4355029", "title": "Genetic factors in chronic remittent Friend disease.", "content": "Genetic factors in chronic remittent Friend disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355029"}
{"pmid": "4355030", "title": "Competitive DNA-RNA hybridization of nuclear and microsomal RNA in normal, neoplastic, and neonatal liver tissue.", "content": "Competitive DNA-RNA hybridization of nuclear and microsomal RNA in normal, neoplastic, and neonatal liver tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355030"}
{"pmid": "4355031", "title": "Electron microscopic study of lymphatic tissues of mice inoculated with a leukemogenic extract from radiation-induced tumors.", "content": "Electron microscopic study of lymphatic tissues of mice inoculated with a leukemogenic extract from radiation-induced tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355031"}
{"pmid": "4355032", "title": "Collagenolytic activity in malignant melanoma: physiocochemical studies.", "content": "Collagenolytic activity in malignant melanoma: physiocochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355032"}
{"pmid": "4355033", "title": "Transfer RNA methylases and transfer RNA-methylated bases of polyoma virus-transformed and spontaneously transformed mouse culture cells.", "content": "Transfer RNA methylases and transfer RNA-methylated bases of polyoma virus-transformed and spontaneously transformed mouse culture cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355033"}
{"pmid": "4355034", "title": "Expression of tumor-specific antigens in mouse somatic cell hybrids.", "content": "Expression of tumor-specific antigens in mouse somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355034"}
{"pmid": "4355035", "title": "Further observations on the activation and inhibition of lipoprotein lipase by apolipoproteins.", "content": "Further observations on the activation and inhibition of lipoprotein lipase by apolipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355035"}
{"pmid": "4355036", "title": "Mechanisms of activation of cardiac glycogen phosphorylase in ischemia and anoxia.", "content": "Mechanisms of activation of cardiac glycogen phosphorylase in ischemia and anoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355036"}
{"pmid": "4355037", "title": "Contribution of intrarenal generation of prostaglandin to autoregulation of renal blood flow in the dog.", "content": "Contribution of intrarenal generation of prostaglandin to autoregulation of renal blood flow in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355037"}
{"pmid": "4355038", "title": "Differential response of large and small coronary arteries to nitroglycerin and angiotensin. Autoregulation and tachyphylaxis.", "content": "Differential response of large and small coronary arteries to nitroglycerin and angiotensin. Autoregulation and tachyphylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355038"}
{"pmid": "4355039", "title": "Improved techniques for assessment of serum lipoprotein patterns. II. Rapid method for diagnosis of type 3 hyperlipoproteinemia without ultracentrifugation.", "content": "Improved techniques for assessment of serum lipoprotein patterns. II. Rapid method for diagnosis of type 3 hyperlipoproteinemia without ultracentrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355039"}
{"pmid": "4355040", "title": "Rapid determination of ammonia in a perchloric acid supernate from blood, by use of an ammonia-specific electrode.", "content": "Rapid determination of ammonia in a perchloric acid supernate from blood, by use of an ammonia-specific electrode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355040"}
{"pmid": "4355041", "title": "Improved method for determination of triglycerides in serum.", "content": "Improved method for determination of triglycerides in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355041"}
{"pmid": "4355042", "title": "Measurement of carcinoembryonic antigen.", "content": "Measurement of carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355042"}
{"pmid": "4355044", "title": "Simian virus 40-induced retinopathy in the rat.", "content": "Simian virus 40-induced retinopathy in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355044"}
{"pmid": "4355043", "title": "Contact sensitivity in vitro. The production of macrophage inhibition factors from DNCB sensitized lymphocytes by subcellular organelles obtained from DNCB epidermal tissue.", "content": "Contact sensitivity in vitro. The production of macrophage inhibition factors from DNCB sensitized lymphocytes by subcellular organelles obtained from DNCB epidermal tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355043"}
{"pmid": "4355045", "title": "Increased sensitivity to theophylline associated with primary open-angle glaucoma.", "content": "Increased sensitivity to theophylline associated with primary open-angle glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355045"}
{"pmid": "4355046", "title": "Bluetongue virus in exotic ruminants.", "content": "Bluetongue virus in exotic ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355046"}
{"pmid": "4355047", "title": "An epornitic of duck virus enteritis (duck plague) in California.", "content": "An epornitic of duck virus enteritis (duck plague) in California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355047"}
{"pmid": "4355048", "title": "Cheddar cheese as a vehicle for viruses.", "content": "Cheddar cheese as a vehicle for viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355048"}
{"pmid": "4355049", "title": "Characterization of brain cerebrosides at early stages of development in the rat.", "content": "Characterization of brain cerebrosides at early stages of development in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355049"}
{"pmid": "4355050", "title": "Stimulatory effect of L-vasopressin on PMSG-induced ovulation in immature rats.", "content": "Stimulatory effect of L-vasopressin on PMSG-induced ovulation in immature rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355050"}
{"pmid": "4355051", "title": "Activity of mitochondrial enzymes in mouse embryos.", "content": "Activity of mitochondrial enzymes in mouse embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355051"}
{"pmid": "4355052", "title": "Congenital mesoblastic nephroma (leiomyomatous hamartoma): first adult case.", "content": "Congenital mesoblastic nephroma (leiomyomatous hamartoma): first adult case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355052"}
{"pmid": "4355053", "title": "Granular cell myoblastoma of the bladder: report of an additional case.", "content": "Granular cell myoblastoma of the bladder: report of an additional case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355053"}
{"pmid": "4355054", "title": "Massive adrenal hemorrhage in the newborn: 2 surviving cases by surgical treatment.", "content": "Massive adrenal hemorrhage in the newborn: 2 surviving cases by surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355054"}
{"pmid": "4355055", "title": "Benign renal tumors in children: report of a case.", "content": "Benign renal tumors in children: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355055"}
{"pmid": "4355056", "title": "Retroperitoneal lipoblastic tumors in children.", "content": "Retroperitoneal lipoblastic tumors in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355056"}
{"pmid": "4355057", "title": "Some observations on the pathogenesis of Bartter's syndrome.", "content": "Some observations on the pathogenesis of Bartter's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355057"}
{"pmid": "4355058", "title": "Pseudohypoparathyroidism type II: a possible defect in the reception of the cyclic AMP signal.", "content": "Pseudohypoparathyroidism type II: a possible defect in the reception of the cyclic AMP signal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355058"}
{"pmid": "4355059", "title": "Letter: Role of microtubules in lipoprotein secretion by the liver.", "content": "Letter: Role of microtubules in lipoprotein secretion by the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355059"}
{"pmid": "4355060", "title": "Prebiotic activation processes.", "content": "Prebiotic activation processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355060"}
{"pmid": "4355062", "title": "Letter: Ribonucleoprotein particle in epidermis cells as the receptor for juvenile hormone.", "content": "Letter: Ribonucleoprotein particle in epidermis cells as the receptor for juvenile hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355062"}
{"pmid": "4355061", "title": "Peptide formation mediated by cyanate.", "content": "Peptide formation mediated by cyanate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355061"}
{"pmid": "4355063", "title": "Guanidine hydrochloride in the Eaton-Lambert syndrome. Electrophysiologic improvement.", "content": "Guanidine hydrochloride in the Eaton-Lambert syndrome. Electrophysiologic improvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355063"}
{"pmid": "4355065", "title": "Diagnostic open lung biopsy in the critically ill child.", "content": "Diagnostic open lung biopsy in the critically ill child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355065"}
{"pmid": "4355064", "title": "Bacterial meningitis. A symposium. 3. Morbid anatomical changes.", "content": "Bacterial meningitis. A symposium. 3. Morbid anatomical changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355064"}
{"pmid": "4355067", "title": "Distension dacryocystography.", "content": "Distension dacryocystography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355067"}
{"pmid": "4355066", "title": "Debridement of experimental skin burns of pigs with bromelain, a pineapple-stem enzyme.", "content": "Debridement of experimental skin burns of pigs with bromelain, a pineapple-stem enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355066"}
{"pmid": "4355068", "title": "Idiopathic intestinal lymphangiectasis (primary protein-losing enteropathy). Lymphographic verification of enteric and peritoneal leakage of chyle.", "content": "Idiopathic intestinal lymphangiectasis (primary protein-losing enteropathy). Lymphographic verification of enteric and peritoneal leakage of chyle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355068"}
{"pmid": "4355069", "title": "99mTc-diphosphonate concentration in primary breast carcinoma.", "content": "99mTc-diphosphonate concentration in primary breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355069"}
{"pmid": "4355071", "title": "Ultrasonic holography. A promising medical imaging tool.", "content": "Ultrasonic holography. A promising medical imaging tool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355071"}
{"pmid": "4355070", "title": "Suppression of 99mTc-pertechnetate uptake in a choroid plexus papilloma.", "content": "Suppression of 99mTc-pertechnetate uptake in a choroid plexus papilloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355070"}
{"pmid": "4355072", "title": "Evaluation of 99mTc-pyrophosphate as a bone imaging agent.", "content": "Evaluation of 99mTc-pyrophosphate as a bone imaging agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355072"}
{"pmid": "4355073", "title": "Comparison of growth acceleration of pituitary dwarfs treated with anabolic steroid and thyroid hormone with normal growth spurt.", "content": "Comparison of growth acceleration of pituitary dwarfs treated with anabolic steroid and thyroid hormone with normal growth spurt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355073"}
{"pmid": "4355074", "title": "Paradoxical response of plasma cortisol to pulse intravenous injection of synthetic corticotrophin and dibutyryl cyclic adenosine 3',5'-monophosphate in adult panhypopituitarism.", "content": "Paradoxical response of plasma cortisol to pulse intravenous injection of synthetic corticotrophin and dibutyryl cyclic adenosine 3',5'-monophosphate in adult panhypopituitarism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355074"}
{"pmid": "4355075", "title": "\"In vivo radioimmunoassay\" of aldosterone.", "content": "\"In vivo radioimmunoassay\" of aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355075"}
{"pmid": "4355076", "title": "The simultaneous assay of cortisol and 17alpha-hydroxyprogesterone in the plasma of patients with congenital adrenal hyperplasia.", "content": "The simultaneous assay of cortisol and 17alpha-hydroxyprogesterone in the plasma of patients with congenital adrenal hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355076"}
{"pmid": "4355077", "title": "The clinical pattern and prognosis of patients with amebic liver abscess and jaundice.", "content": "The clinical pattern and prognosis of patients with amebic liver abscess and jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355077"}
{"pmid": "4355078", "title": "Studies on human conception.", "content": "Studies on human conception. In vitro and clinical research into the mechanisms of human conception is described.  The author discusses his own work and relevant literature in the field.  The points under study include the growth of follicles, the timing of ovulation, the biochemical changes in preovulatory follicles, fertilization and cell-splitting in vitro, and the endocrine control of implantation.  Results of the various clinical experimentation are graphed and tabulated.  It is hoped that such research will add to the accumulated knowledge of human physiology and help in the treatment of certain forms of human infertility.  It was found that mild hyperfolliculation could be achieved by use of hormonal preparations to induce follicular growth and ovulation.  Human menopausal gonadotropins were used to stimulate follicular growth, and human chorionic gonadotropin was used for inducing ovulation.  Follicles near the time of ovulation were expected to have low levels of estrogen and high levels of PGs (prostaglandins).  Assays of steroids in different follicular fluids revealed considerable variation in the levels of estrogen and progesterone.  PGs obviously play an important role in preovulatory follicle biochemistry.  In vitro methods for inducing fertilization and cleavage were also tried.  Areas for further study are outlined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355078"}
{"pmid": "4355079", "title": "Social service casefinding in the hospital--its influence on the utilization of social services.", "content": "Social service casefinding in the hospital--its influence on the utilization of social services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355079"}
{"pmid": "4355081", "title": "Streptozotocin for malignant insulinomas and carcinoid tumor. Report of eight cases and review of the literature.", "content": "Streptozotocin for malignant insulinomas and carcinoid tumor. Report of eight cases and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355081"}
{"pmid": "4355082", "title": "Pituitary gigantism. A case report and review.", "content": "Pituitary gigantism. A case report and review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355082"}
{"pmid": "4355084", "title": "Editorial: Extra-articular lesions of rheumatoid arthritis.", "content": "Editorial: Extra-articular lesions of rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355084"}
{"pmid": "4355083", "title": "Aberrant behavior of phosphofructokinase from otosclerotic stapedes. Biochemical evidence and the metabolic consequences.", "content": "Aberrant behavior of phosphofructokinase from otosclerotic stapedes. Biochemical evidence and the metabolic consequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355083"}
{"pmid": "4355085", "title": "Clinical experience with two new methanesulfonic acid esters of aminoglycols, NSC-140115 and NSC-140117, in the treatment of malignant lymphoma.", "content": "Clinical experience with two new methanesulfonic acid esters of aminoglycols, NSC-140115 and NSC-140117, in the treatment of malignant lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355085"}
{"pmid": "4355092", "title": "Circadian rhythm in the urinary excretion of cyclic 3',5'-adenosine monophosphate in man.", "content": "Circadian rhythm in the urinary excretion of cyclic 3',5'-adenosine monophosphate in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355092"}
{"pmid": "4355091", "title": "Estimation of ACTH reserve on normal and hypopituitary subjects: comparison of oral and intravenous metyrapone with insulin hypoglycemia.", "content": "Estimation of ACTH reserve on normal and hypopituitary subjects: comparison of oral and intravenous metyrapone with insulin hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355091"}
{"pmid": "4355093", "title": "Isolation of angiotensin II binding proteins from normal human plasma by affinity chromatography.", "content": "Isolation of angiotensin II binding proteins from normal human plasma by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355093"}
{"pmid": "4355094", "title": "Release of transmitter from degenerating locust motorneurones.", "content": "Release of transmitter from degenerating locust motorneurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355094"}
{"pmid": "4355095", "title": "Cell-associated nonesterified fatty acid levels and their alteration during lipolysis in the isolated mouse adipose cell.", "content": "Cell-associated nonesterified fatty acid levels and their alteration during lipolysis in the isolated mouse adipose cell. A rapid and flexible method has been developed for measuring cell-associated, probably intracellular, nonesterified fatty acids (CAFA) in isolated mouse adipose cells. A variety of lipolytic agents as well as various concentrations of epinephrine elevate CAFA levels in rough proportion to their stimulation of glycerol and fatty acid release. Insulin reduces epinephrine-elevated CAFA levels. A detailed, quantitative study of the relationship among lipolytic activity, CAFA levels, and the extracellular molar ratio of fatty acids to albumin has been carried out. Epinephrine-elevated CAFA levels rise linearly with, while epinephrine-stimulated lipolytic activity is independent of, fatty acid to albumin ratios below 2-3. As the ratio increases from 3 to 5, CAFA levels continue to increase, whereas lipolytic activity decreases. Above ratios of 5, fatty acid release almost completely ceases; CAFA levels increase dramatically with residual glycerol release. A temperature-dependent efflux of epinephrine-elevated CAFA can be elicited through blockade of stimulated lipolysis with propranolol, but only in the presence of extracellular fatty acid to albumin ratios below 3. These observations suggest that during stimulated lipolysis, a fatty acid gradient exists between the cell and extracellular serum albumin and that CAFA represent the intracellular component of this gradient. In addition, these observations support the concept that intracellular fatty acids play a role in the feedback regulation of adipose cell function as extracellular fatty acids accumulate during the lipolytic response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355095"}
{"pmid": "4355096", "title": "Bimodal effect of insulin on hormone-stimulated lipolysis: relation to intracellular 3',5'-cyclic adenylic acid and free fatty acid levels.", "content": "Bimodal effect of insulin on hormone-stimulated lipolysis: relation to intracellular 3',5'-cyclic adenylic acid and free fatty acid levels. The present study was undertaken to determine the relationship between the antilipolytic and lipolytic effects of insulin on hormone-stimulated lipolysis and the mechanisms of these reactions. The dose-response curve of norepinephrine-stimulated lipolysis in rat adipocytes was not sigmoidal but biphasic in nature. Intracellular free fatty acid levels were linearly related to lipolytic rate and also described a biphasic profile in response to increments in norepinephrine concentration. Intracellular 3',5'-cyclic AMP levels measured 10 min after addition of increasing concentrations of norepinephrine showed a rise and a plateau followed by a secondary rise. Insulin was antilipolytic at low concentrations of norepinephrine and distinctly lipolytic at high concentrations. The combined antilipolytic and lipolytic effect of insulin is termed the \"bimodal\" effect of insulin on hormone-stimulated lipolysis. The bimodal effect of insulin correlated positively with changes in peak intracellular 3',5'-cyclic AMP levels. In the presence of glucose, insulin invariably enhanced lipolysis. It is suggested that the antilipolytic effect of insulin is achieved by both inhibition of adenyl cyclase activity and activation of low-K(m) 3',5'-cyclic AMP phosphodiesterase, the net effect being a low accumulation of 3',5'-cyclic AMP. On the other hand, the lipolytic effect of insulin probably reflects enhancement of adenyl cyclase activity to an extent that overrides any activation of low-K(m) 3',5'-cyclic AMP phosphodiesterase activity, resulting in an increase in peak adipocyte 3',5'-cyclic AMP levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355096"}
{"pmid": "4355097", "title": "Fatty acid oxidation and esterification in isolated rat hepatocytes: regulation by dibutyryl adenosine 3',5'-cyclic monophosphate.", "content": "Fatty acid oxidation and esterification in isolated rat hepatocytes: regulation by dibutyryl adenosine 3',5'-cyclic monophosphate. Isolated rat hepatocytes rapidly utilized [(14)C]palmitate and, in particular, synthesized large amounts of neutral lipids from palmitate. Incorporation into cellular lipids occurred at a linear rate proportional to the medium concentration of fatty acids. Oxidation of [(14)C]palmitate to CO(2) increased with time and was much slower than palmitate esterification. Since [(14)C]acetate and [(14)C]glucose were oxidized to CO(2) at a linear rate, the lag in fatty acid oxidation to CO(2) did not involve enzymatic steps subsequent to acetate formation. The relative contribution of palmitate to esterification and to CO(2) formation depended upon the molar ratio of palmitate to albumin (v) and the length of incubation. Dibutyryl cyclic AMP (1 mM) reduced the oxidation of palmitate and acetate to CO(2) by about 50 and 90%, respectively, but did not alter palmitate esterification. However, equivalent concentrations of sodium butyrate produced similar decreases in CO(2) formation. Dibutyryl cyclic AMP (1 mM) also stimulated palmitate oxidation to water-soluble products, principally ketone bodies, by 50-100%. Sodium butyrate exerted no effect, while monobutyryl cyclic AMP and cyclic AMP both stimulated this pathway significantly. These results indicate that both v and dibutyryl cyclic AMP regulate the metabolism of fatty acids by isolated hepatocytes and suggest that hormonal stimulation of adenyl cyclase controls hepatic lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355097"}
{"pmid": "4355098", "title": "Letter: The role of antimicrobial agents in the treatment of pertussis.", "content": "Letter: The role of antimicrobial agents in the treatment of pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355098"}
{"pmid": "4355100", "title": "Cell surface changes in virus-induced cell fusion. 2. Changes in cell coat thickness.", "content": "Cell surface changes in virus-induced cell fusion. 2. Changes in cell coat thickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355100"}
{"pmid": "4355102", "title": "Cyclic AMP and cyclic GMP enhance growth of chick embryo fibroblasts.", "content": "Cyclic AMP and cyclic GMP enhance growth of chick embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355102"}
{"pmid": "4355103", "title": "Selective agglutination of pathogenic strains of Entamoeba histolytica induced con A.", "content": "Selective agglutination of pathogenic strains of Entamoeba histolytica induced con A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355103"}
{"pmid": "4355104", "title": "Cushing's syndrome and pregnancy.", "content": "Cushing's syndrome and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355104"}
{"pmid": "4355105", "title": "Metastatic cancer of the pituitary gland.", "content": "Metastatic cancer of the pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355105"}
{"pmid": "4355106", "title": "Effects of ethanol on amino-acid uptake and utilization by the liver and other organs of rats.", "content": "Effects of ethanol on amino-acid uptake and utilization by the liver and other organs of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355106"}
{"pmid": "4355108", "title": "Adenosine 3',5'-monophosphate metabolism in the liver in experimental hemorrhagic shock.", "content": "Adenosine 3',5'-monophosphate metabolism in the liver in experimental hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355108"}
{"pmid": "4355109", "title": "Spontaneous rupture of the liver caused by hepatomas.", "content": "Spontaneous rupture of the liver caused by hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355109"}
{"pmid": "4355110", "title": "Clinical liver heterotopic (auxiliary) transplantation.", "content": "Clinical liver heterotopic (auxiliary) transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355110"}
{"pmid": "4355111", "title": "5-Bromodeoxyuridine incorporation into simian virus 40 deoxyribonucleic acid. Effects on simian virus 40 replication in monkey cells.", "content": "5-Bromodeoxyuridine incorporation into simian virus 40 deoxyribonucleic acid. Effects on simian virus 40 replication in monkey cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355111"}
{"pmid": "4355112", "title": "Transformation of mammalian cells by DNA-containing viruses following photodynamic inactivation.", "content": "Transformation of mammalian cells by DNA-containing viruses following photodynamic inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355112"}
{"pmid": "4355113", "title": "Crystallization of human rhinovirus 1A.", "content": "Crystallization of human rhinovirus 1A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355113"}
{"pmid": "4355114", "title": "Formation of syncytia in human lymphoblastoid cells infected with type C viruses.", "content": "Formation of syncytia in human lymphoblastoid cells infected with type C viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355114"}
{"pmid": "4355115", "title": "Establishment of repression by bacteriophage lambda: lack of a direct regulatory effect of cyclic AMP.", "content": "Establishment of repression by bacteriophage lambda: lack of a direct regulatory effect of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355115"}
{"pmid": "4355117", "title": "Presence of a thermosensitive step in the course of transformation by SE-polyoma virus.", "content": "Presence of a thermosensitive step in the course of transformation by SE-polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355117"}
{"pmid": "4355116", "title": "The effect of cordycepin on cell transformation by RNA tumor viruses.", "content": "The effect of cordycepin on cell transformation by RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355116"}
{"pmid": "4355118", "title": "Effects of pH on the structure of vesicular stomatitis virus.", "content": "Effects of pH on the structure of vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355118"}
{"pmid": "4355119", "title": "Polypeptide composition of measles and canine distemper viruses.", "content": "Polypeptide composition of measles and canine distemper viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355119"}
{"pmid": "4355122", "title": "A national view of mental health.", "content": "A national view of mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355122"}
{"pmid": "4355123", "title": "Phosphodiesterase inhibition and vascular activity of papaverine metabolites.", "content": "Phosphodiesterase inhibition and vascular activity of papaverine metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355123"}
{"pmid": "4355124", "title": "Analysis of the peristaltic reflex in vitro: effects of some antagonists.", "content": "Analysis of the peristaltic reflex in vitro: effects of some antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355124"}
{"pmid": "4355130", "title": "Attempts to find a specific intranuclear location for replication polyoma virus DNA.", "content": "Attempts to find a specific intranuclear location for replication polyoma virus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355130"}
{"pmid": "4355131", "title": "Intracellular distribution of steroid glycosidases of rabbit liver.", "content": "Intracellular distribution of steroid glycosidases of rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355131"}
{"pmid": "4355126", "title": "Letter: Comparing serologic data.", "content": "Letter: Comparing serologic data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355126"}
{"pmid": "4355132", "title": "Toxicity, analysis, and production of aspergillic acid and its analogues.", "content": "Toxicity, analysis, and production of aspergillic acid and its analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355132"}
{"pmid": "4355133", "title": "A comparative study of the corneal graft reaction in allo- and xenogeneic models.", "content": "A comparative study of the corneal graft reaction in allo- and xenogeneic models.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355133"}
{"pmid": "4355134", "title": "Editorial: New knowledge of benign essential hypertension.", "content": "Editorial: New knowledge of benign essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355134"}
{"pmid": "4355125", "title": "Renal histology and clinical course of systemic lupus erythematosus. A prospective study.", "content": "Renal histology and clinical course of systemic lupus erythematosus. A prospective study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355125"}
{"pmid": "4355135", "title": "Renin in hypertension: how important as a risk factor?", "content": "Renin in hypertension: how important as a risk factor? An analysis of the plasma renin levels in relation to the incidence of severe cardiovascular complications (coronary thrombosis, stroke, ruptured aortic aneurysm) was made in 325 patients with various types of hypertension. These patients had one to four measurements of plasma renin activity taken under standard conditions of sodium intake and posture in the period 1963-68. The follow-up was 5 to 10 years in the four groups of hypertensive patients (essential hypertension, malignant hypertension, hypertension secondary to renal parenchymatous disease and hypertension caused by, or associated with, renal artery obstruction). For all 325 patients, the incidence of such complications was 23.6, 20.4 and 44.7% in the low, normal and high renin groups. These findings are at variance with the claim that renin constitutes a serious risk factor in hypertensive patients, especially if it is isolated from other parameters such as the level of diastolic pressure, the adequacy of kidney function, the effectiveness of dietary and drug management of hypertension, and especially the presence or absence of atherosclerotic lesions of the large vessels at the time of the renin determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355135"}
{"pmid": "4355136", "title": "Role of cell-mediated immunity in the recovery of cattle from primary and recurrent infections with infectious bovine rhinotracheitis virus.", "content": "Role of cell-mediated immunity in the recovery of cattle from primary and recurrent infections with infectious bovine rhinotracheitis virus. When cattle infected with infectious bovine rhinotracheitis virus (IBRV) were treated 3 months later with a synthetic corticosteroid, consistent recrudescence of the infection was observed. Suppression of cell-mediated immunity, as measured by lymphocyte transformation responses, could be demonstrated at the time of recrudescence. Treatment with adrenocorticotropic hormone and trigeminal neurotomy also resulted in recrudescence of IBRV, but immunosuppression was not detected in these animals. The detection of specific, antigen-induced, lymphocyte transformation responses at the time of recovery from both primary and recurrent infections suggests that cell-mediated immunity may be important in determining the duration and severity of the recurrent infection. However, immunosuppression may not be the direct mechanism of recrudescence. Lesions were not observed in untreated animals, and virus could not be detected in either tissues or secretions. However, both lesions and virus were found consistently after corticosteroid treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355136"}
{"pmid": "4355137", "title": "Immunization of mice with live attenuated encephalomyocarditis virus: local immunity and survival.", "content": "Immunization of mice with live attenuated encephalomyocarditis virus: local immunity and survival. Mice were vaccinated with an attenuated encephalomyocarditis (EMC) virus strain by the intraperitoneal (i.p.) route and by various ways of respiratory administration: aerosol exposure and intratracheal (i.t.) and intranasal (i.n.) instillation. A linear relationship was found between vaccine dose and the resulting serum antibody titer. The effectiveness of the vaccine was determined by measuring the 50% protective doses (ED(50) values) after a lethal challenge with live virulent virus given by the i.p. route. For all three methods of respiratory immunization essentially the same ED(50) value was found, about 200 plaqueforming units (PFU), but i.p. immunization was less effective, the ED(50) value being about 600 PFU. To investigate the protective effect of local immunity, mice were vaccinated i.p. or i.n. and challenged by the i.n. route. The same ED(50) values were found as after i.p. challenge, indicating that the degree of protection afforded by the vaccine depends only on the route of vaccination and not on the route of challenge. This means that protection depends largely on systemic immunity and that local immunity plays only a minor role in this system. The results are discussed in relation to the feasibility of respiratory immunization against animal viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355137"}
{"pmid": "4355138", "title": "Immunity against parainfluenza-3 virus in cattle: anti-neuraminidase activity in serum and nasal secretion.", "content": "Immunity against parainfluenza-3 virus in cattle: anti-neuraminidase activity in serum and nasal secretion. The antigenicity of two parainfluenza=3 virus strains, a \"neuraminidasestrong\" and a \"neuraminidase-weak,\" was compared. For both strains the amount of hemagglutinin units was equal. The antibody responses to neuraminidase and hemagglutinin were measured on samples of serum and nasal secretion and were found to be similar, irrespective of the strain used for immunization. Anti-neuraminidase activity was demonstrated in the gel phase of nasal secretion of immunized cattle. Immunglobulin A was found attached to the peplomers of inhibited virus by immuno-electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355138"}
{"pmid": "4355128", "title": "The presence of a hormone-sensitive cyclase system in the rat aorta and its relation to lipolysis.", "content": "The presence of a hormone-sensitive cyclase system in the rat aorta and its relation to lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355128"}
{"pmid": "4355139", "title": "Persistent Newcastle disease virus infection in embryonic chicken tracheal organ cultures.", "content": "Persistent Newcastle disease virus infection in embryonic chicken tracheal organ cultures. The persistent infection of embryonic chicken tracheal organ cultures with Newcastle disease virus (NDV) is described. Tracheal explants remained morphologically intact and were able to support the replication of NDV for 6 months. Peak titers of released virus occurred at 1 week postinfection, whereas maximal immunofluorescence was not observed until 30 days postinfection. The inoculum titer was not critical, and viral persistence resulted with either of two strains of NDV tested. Serum was not required in the medium for explant viability or to maintain the persistent infection. The presence of a contaminating virus morphologically resembling a leukovirus neither altered the course of infection nor affected the survivability of explants. Although interferon was not detected in the culture medium, persistently infected explants were resistant to heterologous viral challenge, and a similar resistant state could be induced in uninfected explants with exogenous interferon or ultraviolet light-inactivated NDV. No evidence was found to implicate antibody as a regulatory factor in the establishment or maintenance of persistence. The results from electron microscopy and immunofluorescence suggest the cells of the subepithelial connective tissue as the site of NDV persistence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355139"}
{"pmid": "4355141", "title": "Intracellular measurements in a closed hyperbaric chamber.", "content": "Intracellular measurements in a closed hyperbaric chamber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355141"}
{"pmid": "4355140", "title": "Protection of rabbits against local vaccinia virus infection by Brucella abortus and polyacrylic acid in the absence of systemic interferon production.", "content": "Protection of rabbits against local vaccinia virus infection by Brucella abortus and polyacrylic acid in the absence of systemic interferon production. Brucella abortus and polyacrylic acid, two agents whose interferon-inducing capacity in the mouse has been well established, failed to stimulate circulating interferon production in rabbits, yet protected rabbits against local vaccinia virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355140"}
{"pmid": "4355142", "title": "A laboratory program for bioinorganic chemistry.", "content": "A laboratory program for bioinorganic chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355142"}
{"pmid": "4355143", "title": "Alveolar cell carcinoma.", "content": "Alveolar cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355143"}
{"pmid": "4355144", "title": "Drug-albumin interactions using spin labeling.", "content": "Drug-albumin interactions using spin labeling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355144"}
{"pmid": "4355127", "title": "Acid mucosubstances underlying lipid deposits in ageing tendons and atherosclerotic arteries.", "content": "Acid mucosubstances underlying lipid deposits in ageing tendons and atherosclerotic arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355127"}
{"pmid": "4355145", "title": "Effect of stimulation and acetylcholine on 32P and 14C incorporation into phospholipids of eel electroplax.", "content": "Effect of stimulation and acetylcholine on 32P and 14C incorporation into phospholipids of eel electroplax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355145"}
{"pmid": "4355146", "title": "The mitochondrial derivative of the spermatozoon of Drosophila before and after fertilization.", "content": "The mitochondrial derivative of the spermatozoon of Drosophila before and after fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355146"}
{"pmid": "4355147", "title": "Correlations in differentiation of protophloem sieve elements of Allium cepa root.", "content": "Correlations in differentiation of protophloem sieve elements of Allium cepa root.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355147"}
{"pmid": "4355150", "title": "Sphingolipid fatty acid composition of rat brain \"membranous sacs\".", "content": "Sphingolipid fatty acid composition of rat brain \"membranous sacs\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355150"}
{"pmid": "4355151", "title": "Effect of biliary obstruction on canine plasma and biliary lipids.", "content": "Effect of biliary obstruction on canine plasma and biliary lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355151"}
{"pmid": "4355153", "title": "Letter: Electron microscope autoradiography of kidney after administration of 210Pb in mice.", "content": "Letter: Electron microscope autoradiography of kidney after administration of 210Pb in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355153"}
{"pmid": "4355154", "title": "Structural analysis of the highly hydrogen bonded B3 fragment of 28S rRNA of Novikoff hepatoma ascites cells.", "content": "Structural analysis of the highly hydrogen bonded B3 fragment of 28S rRNA of Novikoff hepatoma ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355154"}
{"pmid": "4355155", "title": "Quantitative distribution of lipids in mouse total liver, mitochondria and microsomes.", "content": "Quantitative distribution of lipids in mouse total liver, mitochondria and microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355155"}
{"pmid": "4355156", "title": "Electrophysiological and behavioral effects of electrical stimulation  of the raphe nuclei in cats.", "content": "Electrophysiological and behavioral effects of electrical stimulation  of the raphe nuclei in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355156"}
{"pmid": "4355157", "title": "The electroencephalogram of sheep and goats with special reference to rumination.", "content": "The electroencephalogram of sheep and goats with special reference to rumination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355157"}
{"pmid": "4355158", "title": "Ultrastructure of pig tubal ova. The unfertilized and pronuclear stage.", "content": "Ultrastructure of pig tubal ova. The unfertilized and pronuclear stage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355158"}
{"pmid": "4355160", "title": "The haemocytes of Calliphora erythrocephala (Meig.) (Diptera).", "content": "The haemocytes of Calliphora erythrocephala (Meig.) (Diptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355160"}
{"pmid": "4355159", "title": "Evidence for the existence of serotonin-, dopamine-, and noradrenaline-containing neurons in the gut of Lampetra fluviatilis.", "content": "Evidence for the existence of serotonin-, dopamine-, and noradrenaline-containing neurons in the gut of Lampetra fluviatilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355159"}
{"pmid": "4355161", "title": "The rostral pars distalis of the pituitary gland of the freshwater and marine alewife (Alosa pseudoharengus). A light and electron microscope study.", "content": "The rostral pars distalis of the pituitary gland of the freshwater and marine alewife (Alosa pseudoharengus). A light and electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355161"}
{"pmid": "4355163", "title": "The neurohypophysis of the crested newt. 3. Fine structure of the median eminence.", "content": "The neurohypophysis of the crested newt. 3. Fine structure of the median eminence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355163"}
{"pmid": "4355165", "title": "Age changes in the centrally and peripherally located sensory neurons in rat.", "content": "Age changes in the centrally and peripherally located sensory neurons in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355165"}
{"pmid": "4355169", "title": "Encephalomyocarditis (EMC) virus infection of the mouse aorta. An ultrastructural study.", "content": "Encephalomyocarditis (EMC) virus infection of the mouse aorta. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355169"}
{"pmid": "4355170", "title": "Epidemiology of respiratory syncytial virus infection in Washington, D.C. II. Infection and disease with respect to age, immunologic status, race and sex.", "content": "Epidemiology of respiratory syncytial virus infection in Washington, D.C. II. Infection and disease with respect to age, immunologic status, race and sex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355170"}
{"pmid": "4355171", "title": "Rheumatoid pneumoconiosis. Documentation of onset and pathogenic considerations.", "content": "Rheumatoid pneumoconiosis. Documentation of onset and pathogenic considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355171"}
{"pmid": "4355172", "title": "The relationship of erythromonocytic leukemia to other myeloproliferative disorders.", "content": "The relationship of erythromonocytic leukemia to other myeloproliferative disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355172"}
{"pmid": "4355173", "title": "Renin-angiotensin system during labor: evaluation of renin activity in normal, pre-eclamptic, and pre-existing hypertensive patients.", "content": "Renin-angiotensin system during labor: evaluation of renin activity in normal, pre-eclamptic, and pre-existing hypertensive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355173"}
{"pmid": "4355174", "title": "The role of cortisol in human parturition.", "content": "The role of cortisol in human parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355174"}
{"pmid": "4355175", "title": "Effects of hyperosmolality on transmural sodium transport in the toad bladder.", "content": "Effects of hyperosmolality on transmural sodium transport in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355175"}
{"pmid": "4355176", "title": "Ion transport in rabbit ileal mucosa. 3. Effects of catecholamines.", "content": "Ion transport in rabbit ileal mucosa. 3. Effects of catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355176"}
{"pmid": "4355177", "title": "Ion transport in rabbit ileal mucosa. IV. Bicarbonate secretion.", "content": "Ion transport in rabbit ileal mucosa. IV. Bicarbonate secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355177"}
{"pmid": "4355178", "title": "Effects of caffeine on neuromuscular transmission in the rat.", "content": "Effects of caffeine on neuromuscular transmission in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355178"}
{"pmid": "4355180", "title": "Ornithine decarboxylase stimulation by 3',5'-cyclic AMP in oviduct of Coturnix quail.", "content": "Ornithine decarboxylase stimulation by 3',5'-cyclic AMP in oviduct of Coturnix quail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355180"}
{"pmid": "4355179", "title": "Mucosal cyclic AMP and secretion in the dog stomach.", "content": "Mucosal cyclic AMP and secretion in the dog stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355179"}
{"pmid": "4355181", "title": "Phosphorylase, calcium, and cyclic AMP in smooth-muscle contraction.", "content": "Phosphorylase, calcium, and cyclic AMP in smooth-muscle contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355181"}
{"pmid": "4355183", "title": "The effects of protein synthesis inhibition on sleep in mice.", "content": "The effects of protein synthesis inhibition on sleep in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355183"}
{"pmid": "4355184", "title": "The relationship of REM sleep with learning and memory in mice.", "content": "The relationship of REM sleep with learning and memory in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355184"}
{"pmid": "4355185", "title": "Skin window macrophages in malignant lymphomas.", "content": "Skin window macrophages in malignant lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355185"}
{"pmid": "4355186", "title": "Glucose-mediated insulin release: 3',5' cAMP phosphodiesterase.", "content": "Glucose-mediated insulin release: 3',5' cAMP phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355186"}
{"pmid": "4355187", "title": "Insulin and insulinlike activity in extracts of tumors associated with hypoglycemia.", "content": "Insulin and insulinlike activity in extracts of tumors associated with hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355187"}
{"pmid": "4355188", "title": "Propanidid (Epontol)--a new activation method in electroencephalography.", "content": "Propanidid (Epontol)--a new activation method in electroencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355188"}
{"pmid": "4355189", "title": "Studies of the habenulo-interpeduncular pathway in cats.", "content": "Studies of the habenulo-interpeduncular pathway in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355189"}
{"pmid": "4355190", "title": "Enzymes of cholesterol ester metabolism in the brain of mutant mice, quaking and jimpy.", "content": "Enzymes of cholesterol ester metabolism in the brain of mutant mice, quaking and jimpy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355190"}
{"pmid": "4355191", "title": "Concerning recurrent collaterals and afferent fibers in the hypoglossal nerve of the rat.", "content": "Concerning recurrent collaterals and afferent fibers in the hypoglossal nerve of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355191"}
{"pmid": "4355192", "title": "Stature and aging.", "content": "Stature and aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355192"}
{"pmid": "4355193", "title": "The equilibrium constants of the adenosine triphosphate hydrolysis and the adenosine triphosphate-citrate lyase reactions.", "content": "The equilibrium constants of the adenosine triphosphate hydrolysis and the adenosine triphosphate-citrate lyase reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355193"}
{"pmid": "4355182", "title": "Carcinoma in pleomorphic adenomas of salivary glands.", "content": "Carcinoma in pleomorphic adenomas of salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355182"}
{"pmid": "4355194", "title": "Characteristics of a soluble gonadotropin receptor from the rat testis.", "content": "Characteristics of a soluble gonadotropin receptor from the rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355194"}
{"pmid": "4355195", "title": "The 3'-terminal heptanucleotide sequence of the l strand of T7 deoxyribonucleic acid.", "content": "The 3'-terminal heptanucleotide sequence of the l strand of T7 deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355195"}
{"pmid": "4355196", "title": "Adenosine cyclic 3':5'-monophosphate-mediated transport of neutral and dibasic amino acids in jejunal mucosa.", "content": "Adenosine cyclic 3':5'-monophosphate-mediated transport of neutral and dibasic amino acids in jejunal mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355196"}
{"pmid": "4355198", "title": "Partial purification and characterization of nicotinamide adenine dinucleotide kinase from sea urchin eggs.", "content": "Partial purification and characterization of nicotinamide adenine dinucleotide kinase from sea urchin eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355198"}
{"pmid": "4355197", "title": "Isolation of a disulfide-stabilized, three-chain polypeptide fragment unique to the precursor of human collagen.", "content": "Isolation of a disulfide-stabilized, three-chain polypeptide fragment unique to the precursor of human collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355197"}
{"pmid": "4355199", "title": "Selective acylation of 1-acylglycerophosphorylinositol by rat brain microsomes. Comparison with 1-acylglycerophosphorylcholine.", "content": "Selective acylation of 1-acylglycerophosphorylinositol by rat brain microsomes. Comparison with 1-acylglycerophosphorylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355199"}
{"pmid": "4355200", "title": "Oligomycin resistance of mitochondrial adenosine triphosphatase in a pleiotropic chromosomal mutant of a \"petite-negative\" yeast, Schizosaccharomyces pombe.", "content": "Oligomycin resistance of mitochondrial adenosine triphosphatase in a pleiotropic chromosomal mutant of a \"petite-negative\" yeast, Schizosaccharomyces pombe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355200"}
{"pmid": "4355202", "title": "Regulation of glutamate metabolism and interactions with the citric acid cycle in rat heart mitochondria.", "content": "Regulation of glutamate metabolism and interactions with the citric acid cycle in rat heart mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355202"}
{"pmid": "4355201", "title": "An effect of insulin on cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in fat cells.", "content": "An effect of insulin on cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355201"}
{"pmid": "4355203", "title": "Substrate-induced difference spectral, electron paramagnetic resonance, and enzymatic properties of cholesterol-depleted mitochondrial cytochrome P-450 of bovine adrenal cortex.", "content": "Substrate-induced difference spectral, electron paramagnetic resonance, and enzymatic properties of cholesterol-depleted mitochondrial cytochrome P-450 of bovine adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355203"}
{"pmid": "4355205", "title": "Oestrogen receptors in the mammary gland of the lactating rat.", "content": "Oestrogen receptors in the mammary gland of the lactating rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355205"}
{"pmid": "4355204", "title": "Steroid metabolism by adult rat adrenocortical cells in monolayer culture.", "content": "Steroid metabolism by adult rat adrenocortical cells in monolayer culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355204"}
{"pmid": "4355206", "title": "Mechanism of oestradiol action on the rat uterus: independence of cyclic AMP, prostaglandin E2 and beta-adrenergic mediation.", "content": "Mechanism of oestradiol action on the rat uterus: independence of cyclic AMP, prostaglandin E2 and beta-adrenergic mediation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355206"}
{"pmid": "4355207", "title": "Intrinsic stimulatory action of follicle-stimulating hormone on ovarian adenylate cyclase.", "content": "Intrinsic stimulatory action of follicle-stimulating hormone on ovarian adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355207"}
{"pmid": "4355208", "title": "Evaluation of the efficacy of ascorbic acid in prophylaxis of induced rhinovirus 44 infection in man.", "content": "Evaluation of the efficacy of ascorbic acid in prophylaxis of induced rhinovirus 44 infection in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355208"}
{"pmid": "4355209", "title": "Bactericidal antibody in serum during infection with Bordetalla pertussis.", "content": "Bactericidal antibody in serum during infection with Bordetalla pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355209"}
{"pmid": "4355210", "title": "Absence of relationship of fecal Clostridium perfringens to rheumatoid arthritis and rheumatoid variants.", "content": "Absence of relationship of fecal Clostridium perfringens to rheumatoid arthritis and rheumatoid variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355210"}
{"pmid": "4355211", "title": "Glutamate-mediated respiration in tumors.", "content": "Glutamate-mediated respiration in tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355211"}
{"pmid": "4355212", "title": "Pathology of intestinal neoplasms and other lesions in rats exposed to azoxymethane.", "content": "Pathology of intestinal neoplasms and other lesions in rats exposed to azoxymethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355212"}
{"pmid": "4355213", "title": "Brief communication: carcinoembryonic antigen in colon cancer: absence in perchloric acid precipitates of plasma.", "content": "Brief communication: carcinoembryonic antigen in colon cancer: absence in perchloric acid precipitates of plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355213"}
{"pmid": "4355214", "title": "Brief communication: antigenic relationship between Mycobacterium bovis (BCG) and a guinea pig hepatoma.", "content": "Brief communication: antigenic relationship between Mycobacterium bovis (BCG) and a guinea pig hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355214"}
{"pmid": "4355216", "title": "Freeze-etching, scanning, and thin-section electron microscopic studies of the \"hairy\" leukocytes in leukemic reticuloendotheliosis.", "content": "Freeze-etching, scanning, and thin-section electron microscopic studies of the \"hairy\" leukocytes in leukemic reticuloendotheliosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355216"}
{"pmid": "4355215", "title": "Clinical and laboratory investigations on man: systemic administration of potent interferon to man.", "content": "Clinical and laboratory investigations on man: systemic administration of potent interferon to man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355215"}
{"pmid": "4355217", "title": "Difference in heat stability of antigens associated with Epstein-Barr virus, demonstrated by immunodiffusion.", "content": "Difference in heat stability of antigens associated with Epstein-Barr virus, demonstrated by immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355217"}
{"pmid": "4355218", "title": "Expression of malignancy in interspecies Chinese hamster X mouse cell hybrids.", "content": "Expression of malignancy in interspecies Chinese hamster X mouse cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355218"}
{"pmid": "4355219", "title": "Pathogenesis of feline viral fibrosarcomas: dose and age effects.", "content": "Pathogenesis of feline viral fibrosarcomas: dose and age effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355219"}
{"pmid": "4355220", "title": "A possibility of distinction between normal and neoplastic cells through transplantation into chick blastoderms.", "content": "A possibility of distinction between normal and neoplastic cells through transplantation into chick blastoderms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355220"}
{"pmid": "4355221", "title": "Protective effect of the double-stranded polyribonucleotide, polyinosinic polycytidylic acid, against rat erythroblastosis induced by murine erythroblastosis virus.", "content": "Protective effect of the double-stranded polyribonucleotide, polyinosinic polycytidylic acid, against rat erythroblastosis induced by murine erythroblastosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355221"}
{"pmid": "4355222", "title": "Cell-associated virions and nucleoids of a murine leukemia virus.", "content": "Cell-associated virions and nucleoids of a murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355222"}
{"pmid": "4355223", "title": "Tumorigenicity and antigenicity of mouse cells infected with Simian virus 40. I. Relationship of growth in vitro and in vivo in immunosuppressed and immunocompetent recipients.", "content": "Tumorigenicity and antigenicity of mouse cells infected with Simian virus 40. I. Relationship of growth in vitro and in vivo in immunosuppressed and immunocompetent recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355223"}
{"pmid": "4355225", "title": "Oncogenic Marek's disease herpesvirus in avian encephalitis (temporary paralysis).", "content": "Oncogenic Marek's disease herpesvirus in avian encephalitis (temporary paralysis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355225"}
{"pmid": "4355224", "title": "Nonimmune rosette formation by lymphoma and leukemia cells from Herpesvirus saimiri-infected owl monkeys.", "content": "Nonimmune rosette formation by lymphoma and leukemia cells from Herpesvirus saimiri-infected owl monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355224"}
{"pmid": "4355226", "title": "Tumors in CF-1 mice exposed for six consecutive generations to DDT.", "content": "Tumors in CF-1 mice exposed for six consecutive generations to DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355226"}
{"pmid": "4355227", "title": "Tumors of the kidneys, synovia, exocrine pancreas and nasal cavity in BALB-cf-Cd mice.", "content": "Tumors of the kidneys, synovia, exocrine pancreas and nasal cavity in BALB-cf-Cd mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355227"}
{"pmid": "4355228", "title": "Granular cell myoblastoma occurring in the lower lip.", "content": "Granular cell myoblastoma occurring in the lower lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355228"}
{"pmid": "4355229", "title": "Alphafetoprotein in testicular tumors.", "content": "Alphafetoprotein in testicular tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355229"}
{"pmid": "4355231", "title": "How mercurial diuretics work.", "content": "How mercurial diuretics work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355231"}
{"pmid": "4355230", "title": "The mineral content of inguinal nodes in barefoot people with and without elephantiasis of the legs.", "content": "The mineral content of inguinal nodes in barefoot people with and without elephantiasis of the legs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355230"}
{"pmid": "4355232", "title": "Parathyroid hormone secretion in familial vitamin-D-resistant rickets.", "content": "Parathyroid hormone secretion in familial vitamin-D-resistant rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355232"}
{"pmid": "4355233", "title": "Thermal synthesis of amino acids from a simulated primitive atmosphere.", "content": "Thermal synthesis of amino acids from a simulated primitive atmosphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355233"}
{"pmid": "4355234", "title": "Specific neutralization of human hepatitis type A in marmoset monkeys.", "content": "Specific neutralization of human hepatitis type A in marmoset monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355234"}
{"pmid": "4355235", "title": "Transformation of mammalian cells in vitro by low doses of X-rays.", "content": "Transformation of mammalian cells in vitro by low doses of X-rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355235"}
{"pmid": "4355236", "title": "Acetylcholine release within the cat striatum during the sleep-wakefulness cycle.", "content": "Acetylcholine release within the cat striatum during the sleep-wakefulness cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355236"}
{"pmid": "4355237", "title": "Complementation analysis of maple syrup urine disease in heterokaryons derived from cultured human fibroblasts.", "content": "Complementation analysis of maple syrup urine disease in heterokaryons derived from cultured human fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355237"}
{"pmid": "4355238", "title": "Role of inositol cyclic phosphate in stimulated tissues.", "content": "Role of inositol cyclic phosphate in stimulated tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355238"}
{"pmid": "4355239", "title": "Letter: Accelerated substrate cycling of fructose-6-phosphate in the muscle of malignant hyperthermic pigs.", "content": "Letter: Accelerated substrate cycling of fructose-6-phosphate in the muscle of malignant hyperthermic pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355239"}
{"pmid": "4355240", "title": "Renin in anesthetized rats.", "content": "Renin in anesthetized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355240"}
{"pmid": "4355242", "title": "Morphologically \"differentiated\" mouse neuroblastoma cells induced by noncyclic AMP agents: levels of cyclic AMP, nucleic acid and protein.", "content": "Morphologically \"differentiated\" mouse neuroblastoma cells induced by noncyclic AMP agents: levels of cyclic AMP, nucleic acid and protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355242"}
{"pmid": "4355241", "title": "Analysis of tremorgenic effects of intracaudate serotonin.", "content": "Analysis of tremorgenic effects of intracaudate serotonin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355241"}
{"pmid": "4355244", "title": "Maturity of the pituitary-adrenal axis in the newborn dog.", "content": "Maturity of the pituitary-adrenal axis in the newborn dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355244"}
{"pmid": "4355243", "title": "The selective inhibition of secondary IgE antibody response in mice by dibutyryl adenosine 3',5'-cyclic monophosphoric acid and theophylline.", "content": "The selective inhibition of secondary IgE antibody response in mice by dibutyryl adenosine 3',5'-cyclic monophosphoric acid and theophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355243"}
{"pmid": "4355245", "title": "Effects of urethane on pituitary-adrenal function in the rat.", "content": "Effects of urethane on pituitary-adrenal function in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355245"}
{"pmid": "4355246", "title": "Induction of immunity in man by crystalline adenovirus type 5 capsid antigens.", "content": "Induction of immunity in man by crystalline adenovirus type 5 capsid antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355246"}
{"pmid": "4355247", "title": "Maternal-fetal endocrine interrelations in the rat: effects of cyclic and dibutyryl cyclic AMP on pituitary-thyroid and adrenocortical systems in mother and neonate.", "content": "Maternal-fetal endocrine interrelations in the rat: effects of cyclic and dibutyryl cyclic AMP on pituitary-thyroid and adrenocortical systems in mother and neonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355247"}
{"pmid": "4355249", "title": "Correspondence: On the ESR spectra of radicals produced by the reaction of OH with uracils.", "content": "Correspondence: On the ESR spectra of radicals produced by the reaction of OH with uracils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355249"}
{"pmid": "4355248", "title": "Sites of x-irradiation-induced damage in the microsomal drug metabolizing enzyme system of rat liver during development.", "content": "Sites of x-irradiation-induced damage in the microsomal drug metabolizing enzyme system of rat liver during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355248"}
{"pmid": "4355250", "title": "A semiempirical study of the sugar radicals in irradiated cytidylic acid b and deoxyadenosine.", "content": "A semiempirical study of the sugar radicals in irradiated cytidylic acid b and deoxyadenosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355250"}
{"pmid": "4355252", "title": "Invasive mole and gestational choriocarcinoma in Denmark, 1940-1969. Biological and clinical aspects.", "content": "Invasive mole and gestational choriocarcinoma in Denmark, 1940-1969. Biological and clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355252"}
{"pmid": "4355253", "title": "Primary hepatic tumors in infancy and childhood.", "content": "Primary hepatic tumors in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355253"}
{"pmid": "4355254", "title": "Entrapment of ophthalmic ointment in the cornea.", "content": "Entrapment of ophthalmic ointment in the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355254"}
{"pmid": "4355255", "title": "Successfully treated postoperative Candida parakrusei endophthalmitis.", "content": "Successfully treated postoperative Candida parakrusei endophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355255"}
{"pmid": "4355257", "title": "Juvenile angiofibroma. Review of 120 cases.", "content": "Juvenile angiofibroma. Review of 120 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355257"}
{"pmid": "4355256", "title": "Malignant tumors of the submaxillary gland.", "content": "Malignant tumors of the submaxillary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355256"}
{"pmid": "4355258", "title": "Current surgical management of functioning islet cell tumors of the pancreas.", "content": "Current surgical management of functioning islet cell tumors of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355258"}
{"pmid": "4355259", "title": "Airborne stability of simian virus 40.", "content": "Airborne stability of simian virus 40. The influence of relative humidity on the airborne survival of simian virus 40 (SV40) was studied by allowing virus aerosols to age in rotating drums at 21 or 32 C and at a relative humidity (RH) value ranging from 22 to 88%. Airborne SV40 virus was stable at every RH tested at 21 C, but aerosols maintained at 32 C were inactivated within 60 min at mid-range RH values. The unusual stability at 21 C over a broad RH range indicates that potentially biohazardous situations may occur under laboratory conditions if this virus becomes accidentally airborne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355259"}
{"pmid": "4355260", "title": "Filtration methods for recovering enteroviruses from foods.", "content": "Filtration methods for recovering enteroviruses from foods. A set of simple, rapid filtration methods has been developed for recovering enteroviruses from foods. The methods employ quite inexpensive equipment, and the resulting extract might be concentrated in any of several ways. Three model enteroviruses were apparently recovered with at least 80% efficiency when inoculated, at levels ranging from thousands to one plaque-forming unit per 20-g sample, into eleven foods representing six major food groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355260"}
{"pmid": "4355262", "title": "Influence of parabiosis on tumour growth in tumour bearing animals.", "content": "Influence of parabiosis on tumour growth in tumour bearing animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355262"}
{"pmid": "4355261", "title": "Mass airflow cabinet for control of airborne infection of laboratory rodents.", "content": "Mass airflow cabinet for control of airborne infection of laboratory rodents. A mass airflow cabinet for handling and housing of laboratory rodents has been developed and tested. The unit consists of a high-efficiency particulate air filter and uniform distribution of air at a vertical velocity of 19 cm per s. Animals are maintained without bedding in mesh-bottomed cages that rest on rollers for rotation inside the cabinet. There is an air barrier of 90 cm per s separating the cabinet air from room air. Sampling for airborne bacteria yielded an average of 0.03 colony-forming units (CFU) per ft(3) of air inside the cabinet, whereas 28.8 CFU per ft(3) was simultaneously detected outside the cabinet during housekeeping, a reduction of almost three logs. The efficiency of the air barrier was tested by aerosolization of T3 phage. When phage was aerosolized 5 cm outside the cabinet, no phage could be detected 5 cm inside when the fans were operating; with the fans off an average of 1.6 x 10(4) plaque-forming units (PFU) per ft(3) was detected in six tests. Aerosolization of phage inside the cabinet yielded an average of 9 x 10 PFU per ft(3) outside; an average of 4.1 x 10(6) PFU per ft(3) were detected with the fans not in operation, a reduction of more than four logs. In-use studies on effectiveness showed that the cabinet significantly reduced the incidence of mice originally titer-free to Reo-3 virus. Hemagglutination inhibition antibodies to Reo-3 were detected in 9/22 (42%) mice housed in a conventionally ventilated animal laboratory while no seroconversion was detected in any of 22 mice housed in the mass air flow cabinet in the same laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355261"}
{"pmid": "4355263", "title": "Herpes zoster myelitis. Evidence for viral invasion of spinal cord.", "content": "Herpes zoster myelitis. Evidence for viral invasion of spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355263"}
{"pmid": "4355264", "title": "Asbestos-induced intrathoracic tissue reactions.", "content": "Asbestos-induced intrathoracic tissue reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355264"}
{"pmid": "4355265", "title": "Cytomegalovirus vasculitis with fatal colonic hemorrhage.", "content": "Cytomegalovirus vasculitis with fatal colonic hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355265"}
{"pmid": "4355266", "title": "An ESR study of the active-site conformations of free and immobilized trypsin.", "content": "An ESR study of the active-site conformations of free and immobilized trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355266"}
{"pmid": "4355267", "title": "EPR study of nitric oxide-treated reduced ceruloplasmin.", "content": "EPR study of nitric oxide-treated reduced ceruloplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355267"}
{"pmid": "4355268", "title": "Arabinose (fucose) dehydrogenase from pig liver. I. Isolation and characterization.", "content": "Arabinose (fucose) dehydrogenase from pig liver. I. Isolation and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355268"}
{"pmid": "4355269", "title": "Multiple forms of adenosine 3',5'-cyclic monophosphate-dependent protein kinase from monkey skin.", "content": "Multiple forms of adenosine 3',5'-cyclic monophosphate-dependent protein kinase from monkey skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355269"}
{"pmid": "4355270", "title": "Cellular reaction in trophoblastic tumours.", "content": "Cellular reaction in trophoblastic tumours. The presence of a mononuclear cell reaction to 41 gestational choriocarcinomata, 10 invasive moles and 13 malignant trophoblastic teratomata has been investigated. The intensity of the reaction was graded; there was a significantly better response to therapy and survival rate in those with a \"severe\" cellular reaction than in those with a \"mild\" reaction to gestational choriocarcinoma. The pathological and clinical features of invasive moles showed no relationship with the cellular reaction to the tumour. The cellular reaction to trophoblastic teratomata was generally poor but there was a marked cellular reaction to the tumour of one patient who has enjoyed a sustained remission.The relationship of cellular reaction and response to treatment with other histological and clinical features was examined. With the exception of a positive correlation between the degree of vascular invasion and response to treatment, none was found.It is suggested that an infiltrate of mononuclear cells in gestational choriocarcinoma is probably a response to the presence of tumour antigens. The infiltrate favourably affects the response to chemotherapeutic agents, suggesting that it contributes to tumour cell death and it may be interpreted as an immunological response directed at tumour rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355270"}
{"pmid": "4355272", "title": "The effect of nociceptive cutaneous stimuli on human motoneurons.", "content": "The effect of nociceptive cutaneous stimuli on human motoneurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355272"}
{"pmid": "4355271", "title": "Some EPR signals in tumour tissue.", "content": "Some EPR signals in tumour tissue. Normal and tumour tissues from rats, blood from normal and tumour bearing rats, and normal human blood were examined using the electron paramagnetic resonance (epr) technique. At low temperature a triplet epr signal, which is known to be produced by a NO-haemoprotein complex, was detected in some tumour samples and in decaying normal liver. At room temperature all of the tumour samples examined gave a doublet signal. This signal was also detected in blood but not in other normal tissues. The signal has a g value of 2·0054 ± 0·0002 and a hyperfine splitting of 1·80 ± 0·05 G and is assigned to the ascorbyl free radical. Model experiments suggest that the appearance of detectable concentrations of this radical result from a disturbance of the normal state of the ascorbic acid, dehydroascorbic acid redox system. It was verified that cell division is not responsible for the ascorbyl radical although autolysis may be involved. A possible relationship between the formation of ascorbyl radicals and other paramagnetic species in tumours is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355271"}
{"pmid": "4355273", "title": "Immunologic status in lung cancer.", "content": "Immunologic status in lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355273"}
{"pmid": "4355274", "title": "Radiotherapy for suspected lung cancer not proved by tissue diagnosis.", "content": "Radiotherapy for suspected lung cancer not proved by tissue diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355274"}
{"pmid": "4355275", "title": "Type 4 hyperlipoproteinemia: one theory of atherogenesis.", "content": "Type 4 hyperlipoproteinemia: one theory of atherogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355275"}
{"pmid": "4355276", "title": "Neuro-endocrine correlates of immune response. I. Effects of brain lesions on antibody production, Arthus reactivity and delayed hypersensitivity in the rat.", "content": "Neuro-endocrine correlates of immune response. I. Effects of brain lesions on antibody production, Arthus reactivity and delayed hypersensitivity in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355276"}
{"pmid": "4355277", "title": "Studies with two new phosphodiesterase inhibitors (ICI 58, 301 and ICI 63, 197) on anaphylaxis in guinea pigs, mice and rats.", "content": "Studies with two new phosphodiesterase inhibitors (ICI 58, 301 and ICI 63, 197) on anaphylaxis in guinea pigs, mice and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355277"}
{"pmid": "4355278", "title": "Differentiation of T cells induced by preparations from thymus and by nonthymic agents.", "content": "Differentiation of T cells induced by preparations from thymus and by nonthymic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355278"}
{"pmid": "4355279", "title": "Lymphocyte activation in subacute sclerosing panencephalitis virus and cytomegalovirus infections. In vitro stimulation in response to viral-infected cell lines.", "content": "Lymphocyte activation in subacute sclerosing panencephalitis virus and cytomegalovirus infections. In vitro stimulation in response to viral-infected cell lines. Efforts to stimulate lymphocytes from measles seropositive and two patients with subacute sclerosing panencephalitis (SSPE) with either commercially available measles virus or virus isolated from a known case of SSPE failed to show any significant data using a microculture assay. Similar results were obtained using lymphocytes from two patients with active cytomegalovirus (CMV) infections and CMV seropositive individuals using CMV suspensions. On the other hand, lymphocytes from the patients with subacute sclerosing panencephalitis exhibited in vitro blastogenesis in culture with SSPE virus-infected HeLa cells. Similarly, lymphocytes from the CMV-infected patients demonstrated blastogenesis when cocultivated with CMV-infected WI-38 cells. This affords a new method for determining the cell-mediated immune capacity of patients with \"slow\" virus diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355279"}
{"pmid": "4355280", "title": "Studies on membrane-bound receptors for antigen. Preparation of populations of receptor-depleted lymphocytes.", "content": "Studies on membrane-bound receptors for antigen. Preparation of populations of receptor-depleted lymphocytes. THE EFFECT OF POLYADENYLIC: polyundylic acid complexes (poly A:U) on the amount of antibody on the surface of various populations of mouse lymphoid cells has been investigated by means of a sensitive measure of such activity-the binding by primed cell populations of beta-galactosidase (betaGZ) as an antigen. The sensitivity derives from the liberation of fluorescein from an artificial substrate, fluorescein-di-beta-galactopyranoside (FDbetaG). After incubation with 100 ng/ml of poly A:U, only 40% of the cells previously showing antigen-binding were still active. The optimum range of activity lay between 0.01-1.0 microg/ml poly A:U. Such cells showed increased RNA and protein synthesis as indicated by [(3)H]uridine and [(14)C]amino acid incorporation. The polynucleotide effect was abolished by incubation of the cells with sodium azide or iodoacetate, but not by puromycin. When the proteins on the cell surface were labeled by (125)I, poly A:U caused their release into the medium. Reports by others that the enhancing effect of polynucleotides on the immune response involves the adenylcyclase system are consistent with the finding reported here that reduction of binding by dibutryl 5'-cyclic monophosphoric acid (cAMP) and poly A:U were parallel in extent, and that theophylline and poly A:U acted synergistically in suboptimal concentrations of each.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355280"}
{"pmid": "4355281", "title": "Varicella-zoster virus.", "content": "Varicella-zoster virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355281"}
{"pmid": "4355282", "title": "Experimental human reinfection with herpes simplex virus.", "content": "Experimental human reinfection with herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355282"}
{"pmid": "4355283", "title": "The significance of surface changes in parakeratotic horn.", "content": "The significance of surface changes in parakeratotic horn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355283"}
{"pmid": "4355284", "title": "Early response of lymph node cells to Abelson leukemia virus.", "content": "Early response of lymph node cells to Abelson leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355284"}
{"pmid": "4355285", "title": "Hexachlorophene neuropathy in rats.", "content": "Hexachlorophene neuropathy in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355285"}
{"pmid": "4355286", "title": "Induced protein synthesis and oestradiol binding to the nuclei in the rat uterus.", "content": "Induced protein synthesis and oestradiol binding to the nuclei in the rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355286"}
{"pmid": "4355289", "title": "Cytology and cytochemistry of the scolex gland cells in Diphyllobothrium ditremum (Creplin, 1825).", "content": "Cytology and cytochemistry of the scolex gland cells in Diphyllobothrium ditremum (Creplin, 1825).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355289"}
{"pmid": "4355290", "title": "Ultrastructure of the gonadal wall of the sea cucumber, Leptosynapta clarki (Echinodermata: Holothuroidea).", "content": "Ultrastructure of the gonadal wall of the sea cucumber, Leptosynapta clarki (Echinodermata: Holothuroidea).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355290"}
{"pmid": "4355291", "title": "The granule-containing cell somata in the superior cervical ganglion of the rat, as studied by a serial sampling method for electron microscopy.", "content": "The granule-containing cell somata in the superior cervical ganglion of the rat, as studied by a serial sampling method for electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355291"}
{"pmid": "4355292", "title": "Electron microscopic identification of several types of endocrine cells in the bronchial epithelium of human foetuses.", "content": "Electron microscopic identification of several types of endocrine cells in the bronchial epithelium of human foetuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355292"}
{"pmid": "4355293", "title": "On structural patterns of the lamina propria of human seminiferous tubules.", "content": "On structural patterns of the lamina propria of human seminiferous tubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355293"}
{"pmid": "4355295", "title": "The development of a comprehensive treatment programme. Experiences from the after-care service of a mental hospital.", "content": "The development of a comprehensive treatment programme. Experiences from the after-care service of a mental hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355295"}
{"pmid": "4355296", "title": "Effects of repeated simulated sonic booms of 1.0 PSF on the sleep behavior of young and old subjects.", "content": "Effects of repeated simulated sonic booms of 1.0 PSF on the sleep behavior of young and old subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355296"}
{"pmid": "4355299", "title": "Quantitation of three subpopulations of human serum very low density lipoproteins.", "content": "Quantitation of three subpopulations of human serum very low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355299"}
{"pmid": "4355300", "title": "Practical considerations in angiotensin II antibody production.", "content": "Practical considerations in angiotensin II antibody production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355300"}
{"pmid": "4355301", "title": "Functional and structural changes in liver mitochondria of rats due to CC14 intoxication. I. Studies on state of electron-transport chain.", "content": "Functional and structural changes in liver mitochondria of rats due to CC14 intoxication. I. Studies on state of electron-transport chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355301"}
{"pmid": "4355302", "title": "Functional and structural changes in liver mitochondria of rats due to CCl4 intoxication. II. Respiratory chain and ion transport.", "content": "Functional and structural changes in liver mitochondria of rats due to CCl4 intoxication. II. Respiratory chain and ion transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355302"}
{"pmid": "4355287", "title": "Trophic influences of the nervous system: their biochemical basis and disturbance in skeletal muscle.", "content": "Trophic influences of the nervous system: their biochemical basis and disturbance in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355287"}
{"pmid": "4355297", "title": "Vestibular ototoxicity in primates.", "content": "Vestibular ototoxicity in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355297"}
{"pmid": "4355303", "title": "Some biochemical and pharmacological actions of (-) erythro-meta-(meta-chlorobenzyloxy)-2-(1-aminoethyl)-benzyl alcohol. A derivative of metaraminol.", "content": "Some biochemical and pharmacological actions of (-) erythro-meta-(meta-chlorobenzyloxy)-2-(1-aminoethyl)-benzyl alcohol. A derivative of metaraminol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355303"}
{"pmid": "4355304", "title": "Bradykinin potentiating peptide PCA-Lys-Trp-Ala-Pro. An inhibitor of the pulmonary inactivation of bradykinin and conversion of angiotensin I to II.", "content": "Bradykinin potentiating peptide PCA-Lys-Trp-Ala-Pro. An inhibitor of the pulmonary inactivation of bradykinin and conversion of angiotensin I to II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355304"}
{"pmid": "4355306", "title": "Effect of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane on adrenocorticotropic hormone-induced steroidogenesis in various preparations in vitro of dog adrenal cortex.", "content": "Effect of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane on adrenocorticotropic hormone-induced steroidogenesis in various preparations in vitro of dog adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355306"}
{"pmid": "4355305", "title": "Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung.", "content": "Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355305"}
{"pmid": "4355298", "title": "Inner ear concentrations and ototoxicity of different antibiotics in local and systemic application.", "content": "Inner ear concentrations and ototoxicity of different antibiotics in local and systemic application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355298"}
{"pmid": "4355307", "title": "Effect of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane in vivo on baseline and adrenocorticotropic hormone-induced steroid production in dog adrenal slices.", "content": "Effect of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane in vivo on baseline and adrenocorticotropic hormone-induced steroid production in dog adrenal slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355307"}
{"pmid": "4355308", "title": "Chemical and structural relationships of NAD+ and platinum binding to malate dehydrogenase.", "content": "Chemical and structural relationships of NAD+ and platinum binding to malate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355308"}
{"pmid": "4355310", "title": "Determination of the zero-field splitting in human acid methemoglobin by millimeter and submillimeter ESR experiments.", "content": "Determination of the zero-field splitting in human acid methemoglobin by millimeter and submillimeter ESR experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355310"}
{"pmid": "4355309", "title": "Ferredoxin from Veillonella alcalescens.", "content": "Ferredoxin from Veillonella alcalescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355309"}
{"pmid": "4355311", "title": "Evaluation of dipolar nuclear magnetic resonance shifts in low-spin hemin systems: ferricytochrome c and metmyoglobin cyanide.", "content": "Evaluation of dipolar nuclear magnetic resonance shifts in low-spin hemin systems: ferricytochrome c and metmyoglobin cyanide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355311"}
{"pmid": "4355314", "title": "Chemical modification of Ehrlich ascites tumour cells by periodate and succinic anhydride: effects on metabolism and membrane permeability.", "content": "Chemical modification of Ehrlich ascites tumour cells by periodate and succinic anhydride: effects on metabolism and membrane permeability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355314"}
{"pmid": "4355315", "title": "Amino acid dependent ATP-32PPi exchange measurement. A filter paper disk method.", "content": "Amino acid dependent ATP-32PPi exchange measurement. A filter paper disk method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355315"}
{"pmid": "4355316", "title": "Light induced H+ uptake catalysed by photochemical reaction centres from Rhodopseudomonas spheroides R26.", "content": "Light induced H+ uptake catalysed by photochemical reaction centres from Rhodopseudomonas spheroides R26.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355316"}
{"pmid": "4355317", "title": "Separation of the isoenzymes of lactate dehydrogenase by affinity chromatography using an immobilized AMP-analogue.", "content": "Separation of the isoenzymes of lactate dehydrogenase by affinity chromatography using an immobilized AMP-analogue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355317"}
{"pmid": "4355318", "title": "Synthesis of antibiotics by enzymes from altered growth conditions by Bacillus licheniformis.", "content": "Synthesis of antibiotics by enzymes from altered growth conditions by Bacillus licheniformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355318"}
{"pmid": "4355320", "title": "Spin-spin interaction between iminoxyl radicals localised in antibody combining sites.", "content": "Spin-spin interaction between iminoxyl radicals localised in antibody combining sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355320"}
{"pmid": "4355319", "title": "Purification of estradiol receptor by affinity chromatography. Representative experiments.", "content": "Purification of estradiol receptor by affinity chromatography. Representative experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355319"}
{"pmid": "4355321", "title": "Extrachromosomal element delta in Drosophila melanogaster. IX. Induction of delta-retaining chromosome lines by mutation and gene mapping.", "content": "Extrachromosomal element delta in Drosophila melanogaster. IX. Induction of delta-retaining chromosome lines by mutation and gene mapping. [Delta b], symbolized as [delta(b)], is retained by S(b) chromosome lines and transmitted through the females to their progeny. Transmission through the males is not directly demonstrable (Minamori 1969a). [delta r], symbolized as [delta(r)], is retained by S(r) chromosome lines and transmitted biparentally (Minamori 1971). The multiplication of delta is suppressed at low temperature. All descendant lines derived from S(b)-carrying or S(r)-carrying flies in which the presence of delta cannot be demonstrated gradually accumulate their specific delta factors over many generations (Minamori 1969b, 1972). The delta factors and the sensitive chromosomes are inseparably associated. This observation led to the assumption that delta may be a copy of a chromosomal gene or a certain agent integrated into the chromosome (Minamori 1972). This assumption was examined in the present study by experiments designed to induce delta-retaining sensitive chromosomes, and to map the gene(s) responsible for delta-retention and/or for sensitivity to the killing action of delta factor. One sensitive chromosome which retained [delta(b)] (S(b) chromosome) was obtained in the presence of [delta(b)] out of 2492 insensitive chromosomes which retained no delta; in addition one S(b) chromosome was obtained in the presence of [delta(r)] out of 2131 insensitives. The latter finding suggests that S(b) might be induced by a mutation caused by [delta(b)] or [delta(r)], but not by integration of either delta into the chromosome. Four S(b) chromosomes and one sensitive chromosome which retained [delta(r)] (S(r) chromosome) were obtained out of 1970 insensitives when males carrying the chromosome were fed an alkylating mutagen, ethyl methane sulfonate (EMS). The location of delta-retaining genes was examined by crossing-over experiments employing eight S(b) and five S(r) chromosomes. The genes on these chromosomes were found to be located in the same region or near one another. The gene for [delta(b)], symbolized as Da(b), and the gene for [delta(r)], symbolized as Da(r), are assumed to be multiple alleles of a locus at 2-24.9. The sensitivity of the chromosomes was modified appreciably by recombination; hence, the genes controlling this trait are assumed to be a polygenic system. The findings obtained in this study lead to the hypothesis that delta may be produced by a chromosomal gene (Da) and transmitted extrachromosomally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355321"}
{"pmid": "4355322", "title": "Temperature-sensitive mutations in Drosophila melanogaster. XVII. Heat- and cold-sensitive lethals on chromosome 3.", "content": "Temperature-sensitive mutations in Drosophila melanogaster. XVII. Heat- and cold-sensitive lethals on chromosome 3. Ethyl methanesulfonate-treated third chromosome of Drosophila melanogaster were tested for the presence of dominant and recessive temperature-sensitive lethal mutations at 17 degrees , 22 degrees and 29 degrees C. Out of 1,176 chromosomes tested, no dominant ts lethals, 21 heat-sensitive, 22 cold-sensitive and 10 heat-cold-sensitive lethals were recovered. Heat-cold sensitivity was produced by a single mutation in all cases. Sixty-two percent of the ts lethals were fertile as homozygotes in both sexes. Surprisingly, 88% of the ts lethals mapped between st and Sb, a region straddling the centromere and estimated to comprise 12.9% of the genetic length and 55% of the physical length of chromosome 3. All but one of the heat- and cold-sensitive lethals complemented with each other at their respective restrictive temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355322"}
{"pmid": "4355323", "title": "Xeroradiography of the breast.", "content": "Xeroradiography of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355323"}
{"pmid": "4355324", "title": "Observations on the intranasal vaccination of pregnant cattle against infectious bovine rhinotracheitis and parainfluenza-3 virus infection.", "content": "Observations on the intranasal vaccination of pregnant cattle against infectious bovine rhinotracheitis and parainfluenza-3 virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355324"}
{"pmid": "4355325", "title": "Separation and identification of food dyes. V. Examination of ponceau 6R dyes: extraction of dyes from confectionery products (cakes, cake mixtures and pastries).", "content": "Separation and identification of food dyes. V. Examination of ponceau 6R dyes: extraction of dyes from confectionery products (cakes, cake mixtures and pastries).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355325"}
{"pmid": "4355327", "title": "The interaction between Mycoplasma hominis and poliovirus in cell culture.", "content": "The interaction between Mycoplasma hominis and poliovirus in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355327"}
{"pmid": "4355326", "title": "The tract of Lissauer in relation to sensory transmission in the dorsal horn of spinal cord in the macaque monkey.", "content": "The tract of Lissauer in relation to sensory transmission in the dorsal horn of spinal cord in the macaque monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355326"}
{"pmid": "4355328", "title": "Comparison of the aerosol stabilities of foot-and-mouth disease virus suspended in cell culture fluid or natural fluids.", "content": "Comparison of the aerosol stabilities of foot-and-mouth disease virus suspended in cell culture fluid or natural fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355328"}
{"pmid": "4355329", "title": "Natural selection of mutants of vesicular stomatitis virus by cultured cells of Drosophila melanogaster.", "content": "Natural selection of mutants of vesicular stomatitis virus by cultured cells of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355329"}
{"pmid": "4355331", "title": "Isolation and characterization of virus-resistant mouse embryo fibroblasts.", "content": "Isolation and characterization of virus-resistant mouse embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355331"}
{"pmid": "4355330", "title": "The fragmentation of cellular DNA and the formation of pseudovirions during SV 40 infection of African green monkey kidney cells.", "content": "The fragmentation of cellular DNA and the formation of pseudovirions during SV 40 infection of African green monkey kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355330"}
{"pmid": "4355332", "title": "Concentration of Epstein-Barr virus from cell culture fluids with polyethylene glycol.", "content": "Concentration of Epstein-Barr virus from cell culture fluids with polyethylene glycol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355332"}
{"pmid": "4355333", "title": "Evaluation of the methods of differentiation of variola and alastrim viruses.", "content": "Evaluation of the methods of differentiation of variola and alastrim viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355333"}
{"pmid": "4355334", "title": "Results of a virological study of smallpox convalescents and contacts: short communication.", "content": "Results of a virological study of smallpox convalescents and contacts: short communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355334"}
{"pmid": "4355335", "title": "Serological types of whooping cough bacteria and their connection with immunity in vaccinated children.", "content": "Serological types of whooping cough bacteria and their connection with immunity in vaccinated children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355335"}
{"pmid": "4355336", "title": "Large-scale production of clostridial collagenase and lecithinase C: short communication.", "content": "Large-scale production of clostridial collagenase and lecithinase C: short communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355336"}
{"pmid": "4355337", "title": "Distribution and relationship of precursor Z material to organizing myofibrillar bundles in embryonic rat and hamster ventricular myocytes.", "content": "Distribution and relationship of precursor Z material to organizing myofibrillar bundles in embryonic rat and hamster ventricular myocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355337"}
{"pmid": "4355338", "title": "Glycolytic and tricarboxylic acid cycle intermediates during cardiac arrest and recovery in eu-, hyper- and hypothyroid rats.", "content": "Glycolytic and tricarboxylic acid cycle intermediates during cardiac arrest and recovery in eu-, hyper- and hypothyroid rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355338"}
{"pmid": "4355339", "title": "Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart: a study of myocardial enzyme release.", "content": "Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart: a study of myocardial enzyme release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355339"}
{"pmid": "4355340", "title": "The S-100 protein in water-soluble and pentanol-extractable form in normal human brain and tumours of the human nervous system. A quantitative study.", "content": "The S-100 protein in water-soluble and pentanol-extractable form in normal human brain and tumours of the human nervous system. A quantitative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355340"}
{"pmid": "4355343", "title": "Sporadic acrodystrophic neuropathy.", "content": "Sporadic acrodystrophic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355343"}
{"pmid": "4355342", "title": "Hallervorden-Spatz disease and infantile neuroaxonal dystrophy. Ultrastructural observations, anatomical pathology and nosology.", "content": "Hallervorden-Spatz disease and infantile neuroaxonal dystrophy. Ultrastructural observations, anatomical pathology and nosology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355342"}
{"pmid": "4355344", "title": "Interaction of mouse strain and differential housing upon resistance to Plasmodium berghei.", "content": "Interaction of mouse strain and differential housing upon resistance to Plasmodium berghei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355344"}
{"pmid": "4355346", "title": "The effect of beta-lipoprotein on antistreptolysin-O antibody titers.", "content": "The effect of beta-lipoprotein on antistreptolysin-O antibody titers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355346"}
{"pmid": "4355345", "title": "A radioimmunoassay of the antigen-binding capacity of rabbit antiserum prepared with axenically grown Entamoeba histolytica, Laredo strain.", "content": "A radioimmunoassay of the antigen-binding capacity of rabbit antiserum prepared with axenically grown Entamoeba histolytica, Laredo strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355345"}
{"pmid": "4355349", "title": "International symposium on Hodgkin's disease. Session 2. Histopathology and experimental cytology. Invited discussion: Synthesis and implications for the etiology, pathogenesis and spread of Hodgkin's disease.", "content": "International symposium on Hodgkin's disease. Session 2. Histopathology and experimental cytology. Invited discussion: Synthesis and implications for the etiology, pathogenesis and spread of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355349"}
{"pmid": "4355348", "title": "The activity of some nitroso compounds in the mouse dominant-lethal mutation assay. I. Activity of N-nitroso-N-methylurea, N-methyl-N-nitroso-N'-nitroguanidine and N-nitrosomorpholine.", "content": "The activity of some nitroso compounds in the mouse dominant-lethal mutation assay. I. Activity of N-nitroso-N-methylurea, N-methyl-N-nitroso-N'-nitroguanidine and N-nitrosomorpholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355348"}
{"pmid": "4355352", "title": "International Symposium on Hodgkin's Disease. Session 1. Epidemiology and etiology. Part 2. Virology and serology--new approaches to identification of an etiologic agent.", "content": "International Symposium on Hodgkin's Disease. Session 1. Epidemiology and etiology. Part 2. Virology and serology--new approaches to identification of an etiologic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355352"}
{"pmid": "4355350", "title": "Oncogenic herpesviruses: a selective review and their possible inplications for Hodgkin's disease.", "content": "Oncogenic herpesviruses: a selective review and their possible inplications for Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355350"}
{"pmid": "4355351", "title": "Is Epstein-Barr virus a human tumor virus?", "content": "Is Epstein-Barr virus a human tumor virus?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355351"}
{"pmid": "4355354", "title": "Invited discussion: relationship of titers of Epstein-Barr virus to cell-mediated immunity in patients with Hodgkin's disease.", "content": "Invited discussion: relationship of titers of Epstein-Barr virus to cell-mediated immunity in patients with Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355354"}
{"pmid": "4355353", "title": "Epstein-Barr virus-related serology in Hodgkin's disease.", "content": "Epstein-Barr virus-related serology in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355353"}
{"pmid": "4355356", "title": "Burkitt's lymphoma and heredity.", "content": "Burkitt's lymphoma and heredity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355356"}
{"pmid": "4355357", "title": "Evaluation of the hand and its function.", "content": "Evaluation of the hand and its function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355357"}
{"pmid": "4355358", "title": "Rehabilitation of the hand with motor and sensory impairment.", "content": "Rehabilitation of the hand with motor and sensory impairment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355358"}
{"pmid": "4355359", "title": "The place of microsurgery in hand surgery.", "content": "The place of microsurgery in hand surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355359"}
{"pmid": "4355347", "title": "Interaction of isonicotinoyl hydrazide-adenine-dinucleotide with dehydrogenases.", "content": "Interaction of isonicotinoyl hydrazide-adenine-dinucleotide with dehydrogenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355347"}
{"pmid": "4355360", "title": "Freeze-etching electron microscopy of the lung.", "content": "Freeze-etching electron microscopy of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355360"}
{"pmid": "4355361", "title": "Endometrial cancer. Facts and theories.", "content": "Endometrial cancer. Facts and theories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355361"}
{"pmid": "4355362", "title": "Pediatric familial type II hyperlipoproteinemia: therapy with diet and cholestyramine resin.", "content": "Pediatric familial type II hyperlipoproteinemia: therapy with diet and cholestyramine resin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355362"}
{"pmid": "4355363", "title": "California arbovirus (La Crosse) infections. I. Clinical and laboratory findings in 66 children with meningoencephalitis.", "content": "California arbovirus (La Crosse) infections. I. Clinical and laboratory findings in 66 children with meningoencephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355363"}
{"pmid": "4355364", "title": "Stimulation of steroid secretion in adrenal tumor cells by choleragen.", "content": "Stimulation of steroid secretion in adrenal tumor cells by choleragen. Choleragen, the pure protein from cholera toxin, stimulates steroid secretion by Y-1 adrenal tumor cells in culture. The secreted steroids are the same as seen after addition of adrenocorticotropic hormone. Half-maximal stimulation occurs at 15 pM; stimulation is essentially irreversible by washing and partially reversible (for about 1 hr) by antibody, and there is a latent period of about 60 min before stimulation is seen. Stimulation of adenylate cyclase occurs at about 30-fold higher choleragen concentrations. Gangliosides inhibit choleragen stimulation when added before but not after the toxin. Lipopolysaccharides from Escherichia coli, Salmonella typhosa, and Serratia marcescens also stimulate steroid secretion, but are less potent than choleragen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355364"}
{"pmid": "4355365", "title": "Specific recognition of plasma membranes by embryonic cells.", "content": "Specific recognition of plasma membranes by embryonic cells. Methods have been developed for preparation of plasma membrane fractions from embryonic neural retina and cerebellum. These membrane fractions are specifically bound by intact cells of the original tissue (homotypic binding) and not by cells from the other tissue (heterotypic binding). Aggregation of neural retina cells and cerebellar cells is prevented by addition of homotypic membranes but not by heterotypic membranes. We conclude that, under our assay conditions, these embryonic cells specifically recognize homotypic membranes, and that the specificity of recognition is the same as in the initial step in the process of cellular aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355365"}
{"pmid": "4355366", "title": "Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol.", "content": "Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. The homozygous form of the autosomal dominant disorder, familial hypercholesterolemia, is characterized by the presence in children of profound hypercholesterolemia, cutaneous planar xanthomas, and rapidly progressive coronary vascular disease that usually results in death before age 30 years. Cultured skin fibroblasts from three unrelated subjects with this disorder showed 40- to 60-fold higher activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (EC 1.1.1.34), the rate-controlling enzyme in cholesterol biosynthesis, when compared with fibroblasts of seven control subjects. Enhanced enzyme activity resulted from a complete absence of normal feedback suppression by low-density lipoproteins, which led to a marked overproduction of cholesterol by the mutant cells. The demonstration of apparently identical kinetic properties of the reductase activity of control and mutant cells, coupled with the evidence that this enzyme is normally regulated not by allosteric effectors but by alterations in enzyme synthesis and degradation, suggests that the primary genetic abnormality does not involve the structural gene for the enzyme itself, but a hitherto unidentified gene whose product is necessary for mediation of feedback control by lipoproteins. The fibroblasts of two obligate heterozygotes, the parents of one of the homozygotes, showed a pattern of enzyme regulation intermediate between that of controls and homozygotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355366"}
{"pmid": "4355367", "title": "Prediction of the amount of secondary structure in a globular protein from its aminoacid composition.", "content": "Prediction of the amount of secondary structure in a globular protein from its aminoacid composition. Multiple regression is used to obtain relationships for predicting the amount of secondary structure in a protein molecule from a knowledge of its aminoacid composition. We tested these relations using 18 proteins of known structure, but omitting the protein to be predicted. Independent predictions were made for the two subchains of hemoglobin and insulin. The average errors for these 20 chains or subchains are: helix +/- 7.1%, beta-sheet +/- 6.9%, turn +/- 4.2%, and coil +/- 5.7%. A second set of relations yielding somewhat inferior predictions is given for the case in which Asp and Asn, and Glu and Gln, are not differentiated. Predictions are also listed for 15 proteins for which the aminoacid sequence or tertiary structure is unknown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355367"}
{"pmid": "4355368", "title": "Methionine transfer ribonucleic acids of avian myeloblastosis virus.", "content": "Methionine transfer ribonucleic acids of avian myeloblastosis virus. Chick-embryo cells contain four isoaccepting species of methionine transfer RNA (I-IV). One species (I) is the initiator, tRNA(f) (Met), and the others (II, III, and IV) are the donors of internal methionyl residues (tRNA(m) (Met)). Over 85% of the tRNA(Met) in purified avian myeloblastosis virus consists of one tRNA(m) (Met) species, which resembles host-cell tRNA(Met) IV with respect to chromatographic properties on RPC-5, electrophoretic mobility of the terminal methionyl-oligonucleotide, and activity in cell-free protein synthesis in response to synthetic and natural messenger RNAs. Thus, tRNA(Met) IV of avian myeloblastosis virus is structurally indistinguishable from the corresponding host-cell species, and, although not involved in initiation of viral protein synthesis, is able to function in peptide-chain elongation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355368"}
{"pmid": "4355369", "title": "ATPase and GTPase activities associated with a specific 5S RNA-protein complex.", "content": "ATPase and GTPase activities associated with a specific 5S RNA-protein complex. An RNA-protein complex consisting of 5S RNA and two ribosomal proteins, B-L5 and B-L22, was isolated from Bacillus stearothermophilus ribosomes and found to be active in GTP hydrolysis. This activity was not influenced by elongation factor G. Further analysis of this complex showed that it was also able to hydrolyze ATP. Inhibition studies revealed that ATP was a noncompetitive inhibitor of GTP and that GTP was also a noncompetitive inhibitor of ATP, indicating that two different enzymatic sites were involved. Differences in pH optimum and optimal temperature also point to a twosite enzyme complex. Both enzymatic hydrolyses were inhibited by thiostrepton and fusidic acid, which are known inhibitors of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355369"}
{"pmid": "4355370", "title": "Isolation of circular DNA molecules from whole cellular DNA by use of ATP-dependent deoxyribonuclease.", "content": "Isolation of circular DNA molecules from whole cellular DNA by use of ATP-dependent deoxyribonuclease. A technique is described for isolation of plasmid DNA in closed and open circular double-stranded forms from bacterial cells, by use of ATP-dependent deoxyribonuclease purified from Micrococcus luteus. This DNase, acting only upon linear DNA molecules, degrades all bacterial chromosomal DNA extracted in the linear form. Circular plasmid DNAs are left intact, and are then separated by sedimentation through a sucrose gradient. Unlike previous techniques for analysis of plasmid DNA, this technique can be used to isolate not only closed circular DNA but also open circular DNA. Several plasmids, such as those from phage (lambdadv1 and lambdadv21), a colicinogenic factor (Col E2), a sex factor (F(8)' gal), and \"minicircles\" in Escherichia coli 15, in both the open and closed circular forms, were well separated from chromosomal DNA by this technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355370"}
{"pmid": "4355371", "title": "Linear association between cellular DNA and Epstein-Barr virus DNA in a human lymphoblastoid cell line.", "content": "Linear association between cellular DNA and Epstein-Barr virus DNA in a human lymphoblastoid cell line. High-molecular-weight DNA from cell line Raji (derived from Burkitt's lymphoma), which contains 50-60 copies of Epstein-Barr virus DNA per cell, was fractionated in neutral solution by several cycles of CsCl gradient centrifugation in fixed-angle rotors. Under the fractionation conditions used, intact Epstein-Barr virus DNA from virus particles can be separated from the less-dense cellular DNA. In contrast, a large proportion of the intrinsic Epstein-Barr virus DNA component of Raji cells remains associated with cellular DNA, as determined by nucleic acid hybridization. This interaction, which is resistant to Pronase and phenol treatment, is not the result of aggregation. When the molecular weight of Raji DNA is reduced by hydrodynamic shear, the amount of virus DNA associated with cell DNA decreases. However, some virus DNA still remains bound to fragments of cellular DNA after shearing. The association is completely destroyed in alkaline solution. Molecular weight analysis of Raji DNA after denaturation showed that the alkali-induced release of Epstein-Barr virus DNA was specific and not the result of random single-strand breaks. These data indicate that Epstein-Barr virus DNA is linearly integrated into Raji cell DNA by alkali-labile bonds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355371"}
{"pmid": "4355372", "title": "A mutant of 3T3 cells with cyclic AMP metabolism sensitive to temperature change.", "content": "A mutant of 3T3 cells with cyclic AMP metabolism sensitive to temperature change. A mutant line of 3T3 (mouse fibroblast) cells with temperature-sensitive cyclic AMP (cAMP) metabolism was isolated by selecting for low substratum adhesiveness after a change in temperature. Although the mutant is identical in behavior to the parent cell at constant temperature, a rise or fall in temperature causes a fall in intracellular cAMP levels within seconds, followed by loss of adherence to the culture dish and retraction of cell processes. The mechanism of this fall in cAMP level is at least in part excretion into the medium. The decrease in adhesiveness and retraction of processes can be blocked by analogues of cAMP or agents that elevate intracellular cAMP. The properties of this mutant imply that cAMP is a direct regulator of cell shape and adhesiveness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355372"}
{"pmid": "4355373", "title": "Isolation of Escherichia coli RNA polymerase binding sites on T5 and T7 DNA: further evidence for sigma-dependent recognition of A-T-rich DNA sequences.", "content": "Isolation of Escherichia coli RNA polymerase binding sites on T5 and T7 DNA: further evidence for sigma-dependent recognition of A-T-rich DNA sequences. Previous isolation and analysis of E. coli RNA polymerase (EC 2.7.7.6) binding sites on lambda DNA had demonstrated the existence of a sigma-dependent process of recognition of A-T-rich DNA sequences. We have now extended this finding to T5 and T7 DNA and häve provided evidence for the double-strandedness of the isolated binding sites. The possible equation of these sites to the genetically defined promoters is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355373"}
{"pmid": "4355374", "title": "Mechanisms of lysosomal enzyme release from human leukocytes: microtubule assembly and membrane fusion induced by a component of complement.", "content": "Mechanisms of lysosomal enzyme release from human leukocytes: microtubule assembly and membrane fusion induced by a component of complement. A low-molecular-weight component of complement, similar to or identical with human C5a, interacts with human polymorphonuclear leukocytes treated with cytochalasin B and provokes extracellular release of lysosomal enzymes from these cells. Enzyme release occurs in the absence of particles and is selective in that it is not accompained by release of cytoplasmic enzymes. Cell viability is not altered. Pharmacologic agents that regulate secretion of other inflammatory mediators influenced complement-dependent enzyme release: cAMP and theophylline, prostaglandin E(1) and colchicine inhibited, whereas cGMP enhanced release of enzymes. Ultra-structural histochemistry of cells exposed to this component of complement revealed degranulation, fusion of lysosomal with plasma membranes, and transient assembly of microtubules associated with the release of endogenous myeloperoxidase. Our findings suggest that these intracellular events are common to two important responses of polymorphonuclear leukocytes in inflammation and tissue injury: (a) release of lysosomal hydrolases and (b) chemotaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355374"}
{"pmid": "4355375", "title": "Dynamics of metabolism of normal and virus-transformed chick cells in culture.", "content": "Dynamics of metabolism of normal and virus-transformed chick cells in culture. Application of steady-state tracer technique to normal and transformed cells in tissue culture allows quantitation of intracellular pool sizes of many metabolites and determination of rate of carbon flow along diverse paths. Using a unique apparatus to control the environmental conditions, we show that the glucose carbon flow into tricarboxylic acid cycle intermediates and amino acids is unchanged upon transformation. The increased glycogen formation and glycolysis varies with the glucose concentration in the medium, correlates with the faster glucose transport of transformed cells, and cannot be explained by a difference in growth rate alone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355375"}
{"pmid": "4355376", "title": "Direct evidence for messenger activity of influenza virion RNA.", "content": "Direct evidence for messenger activity of influenza virion RNA. In a cell-free system of Escherichia coli, RNA from influenza virus particles is translated into a polypeptide antigenically identical with the ribonucleoprotein and several more proteins, some of which correspond in size to viral structural components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355376"}
{"pmid": "4355378", "title": "Linear electric field-induced shifts in electron paramagnetic resonance: a new method for study of the ligands of cytochrome P-450.", "content": "Linear electric field-induced shifts in electron paramagnetic resonance: a new method for study of the ligands of cytochrome P-450. The linear electric field shift in paramagnetic resonance has, for the first time, been observed in frozen solutions. The magnitude of the shift parameters, measured at g(max) of the electron paramagnetic resonance absorption envelope, has been used to characterize lowspin ferric heme mercaptide complexes where the nonmercaptide ligand was varied. The magnitude of the shift provides a measure of the difference between the crystal field contribution of the mercaptide and nonmercaptide ligands. In low-spin ferric cytochrome P-450 of rat liver, the presence of an electric field shift indicates a deviation from inversion symmetry and proves that the axial ligands to the heme are not the same. From the magnitude of the shift and its dependence upon the angle between applied electric and magnetic fields, it is suggested that the non-axial ligand to the heme has a crystal field contribution greater than imidazole and smaller than guanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355378"}
{"pmid": "4355377", "title": "Epidermal growth factor: receptors in human fibroblasts and modulation of action by cholera toxin.", "content": "Epidermal growth factor: receptors in human fibroblasts and modulation of action by cholera toxin. Epidermal growth factor (EGF) stimulates both DNA and RNA synthesis in contact-inhibited human fibroblasts. Stimulation of DNA synthesis is observed at concentrations as low as 3 pM, is half-maximal at 70 pM, and is maximal at 300 pM EGF. The action of EGF is similar to that of fetal-calf serum, but is distinguished by the time-course of stimulation and by the ability of serum to stimulate further those cells maximally stimulated by EGF. Cells that synthesize DNA in response to physiological concentrations of EGF (10(-11) to 10(-10) M) are insensitive to physiological concentrations of insulin (10(-11) to 10(-10) M) and respond only minimally to very high concentrations of this hormone (10(-6) M). The biological activity of EGF is paralleled by binding of this peptide to fibroblasts in a specific and saturable manner; the dissociation constant is about 800 pM. The binding of EGF is unaffected by either insulin or cholera toxin. Cholera toxin inhibits the action of both EGF and serum. Suppression of DNA synthesis is observed at 0.02 pM toxin, and is maximal at about 2 pM. Cells treated with cholera toxin at these concentrations appear to be otherwise viable by several criteria. The stimulatory effects of EGF are also inhibited by theophylline and dibutyryl cyclic AMP separately or in combination. These observations indicate that fibroblasts possess receptors for EGF by biological and physicochemical criteria, and suggest that a similar if not identical peptide may be amongst those factors in sera which stimulate cell growth. The possibility is considered that EGF and cholera toxin modulate the ability of a cell to initiate polynucleotide synthesis by way of specific cell-surface interactions which in turn alter the levels of intracellular cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355377"}
{"pmid": "4355379", "title": "Surface antigens common to mouse cleavage embryos and primitive teratocarcinoma cells in culture.", "content": "Surface antigens common to mouse cleavage embryos and primitive teratocarcinoma cells in culture. Syngeneic antisera have been produced in mouse strain 129/Sv-CP males against the primitive cells of teratocarcinoma. These sera react specifically with the primitive cells and are negative on various types of differentiated teratoma cells derived from the same original tumor. They are negative on all other mouse cells tested, with the exception of male germ cells and cleavage-stage embryos. Thus, teratoma cells possess cell-surface antigens in common with normal cleavage-stage embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355379"}
{"pmid": "4355380", "title": "Characterization of RNA from noninfectious virions produced by sarcoma positive-leukemia negative transformed 3T3 cells.", "content": "Characterization of RNA from noninfectious virions produced by sarcoma positive-leukemia negative transformed 3T3 cells. RNA from noninfectious virions produced by two established clonal lines of sarcoma positive-leukemia negative (S+L-)-transformed 3T3 cells has been characterized. RNA from virions or nucleoids of S+L--(C243) cells consisted of three to four sizes: +/-44 S (6%), 28 S (17%), 18 S (38%), and <18 S (39%). 28S virion RNA contained some virus-specific information demonstrable by RNA.DNA hybridization with a DNA probe derived from the RNA-directed DNA polymerase product of murine sarcoma-leukemia virus, while parallel studies indicated that 28S ribosomal RNA from ribosomal subunits of transformed and nontransformed 3T3 cells did not contain virus-specific information. In contrast to the S+L-(C243) virions, RNA from virions or nucleoids of S+L-(D56) cells consisted of five sizes: 80 S (6%), 68 S (8%), 56 S (5%), 28 S (28%), and <28 S (53%). Thermal dissociation studies suggested that this S+L- genome is comprised of 28S RNA subunits. From these studies we postulate that the 28S viral RNA is most probably the monomeric genome of S+L- virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355380"}
{"pmid": "4355387", "title": "Development of chloroplast substructures with apparent secretory roles in the young tobacco leaf.", "content": "Development of chloroplast substructures with apparent secretory roles in the young tobacco leaf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355387"}
{"pmid": "4355388", "title": "The fine structure of iridosphores in the skin of the Atlantic salmon (Salmo salar L.).", "content": "The fine structure of iridosphores in the skin of the Atlantic salmon (Salmo salar L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355388"}
{"pmid": "4355389", "title": "Influence of changes in myocardial contractility on the height and slope of the calibrated apex cardiogram.", "content": "Influence of changes in myocardial contractility on the height and slope of the calibrated apex cardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355389"}
{"pmid": "4355390", "title": "Angiographic diagnosis and differential diagnosis of islet-cell tumors.", "content": "Angiographic diagnosis and differential diagnosis of islet-cell tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355390"}
{"pmid": "4355391", "title": "The many faces of islet cell tumors.", "content": "The many faces of islet cell tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355391"}
{"pmid": "4355393", "title": "Unilobar veno-occlusive disease of the liver. Angiographic demonstration of intrahepatic competition simulating hepatoma.", "content": "Unilobar veno-occlusive disease of the liver. Angiographic demonstration of intrahepatic competition simulating hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355393"}
{"pmid": "4355392", "title": "Obstructive jaundice, the radiologist, the surgeon, and the patient: Caldwell Lecture, 1971.", "content": "Obstructive jaundice, the radiologist, the surgeon, and the patient: Caldwell Lecture, 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355392"}
{"pmid": "4355395", "title": "Conformational studies on guanosine nucleotides and polynucleotides. The effect of the base on the glycosyl and backbone conformations.", "content": "Conformational studies on guanosine nucleotides and polynucleotides. The effect of the base on the glycosyl and backbone conformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355395"}
{"pmid": "4355394", "title": "An improved methodology for preparation of virus-induced double stranded RNA.", "content": "An improved methodology for preparation of virus-induced double stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355394"}
{"pmid": "4355397", "title": "Relations between the ventrolateral thalamic nucleus and motor cortex and their possible role in the central organization of motor control.", "content": "Relations between the ventrolateral thalamic nucleus and motor cortex and their possible role in the central organization of motor control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355397"}
{"pmid": "4355396", "title": "Parameters of stimulation of RNA synthesis and characterization by hybridization in a molluscan neuron.", "content": "Parameters of stimulation of RNA synthesis and characterization by hybridization in a molluscan neuron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355396"}
{"pmid": "4355398", "title": "Postnatal development of thalamic synaptic events underlying evoked recruiting responses and electrocortical activation.", "content": "Postnatal development of thalamic synaptic events underlying evoked recruiting responses and electrocortical activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355398"}
{"pmid": "4355399", "title": "Specific neural connections for the cerebellar control of vestibulo-ocular reflexes.", "content": "Specific neural connections for the cerebellar control of vestibulo-ocular reflexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355399"}
{"pmid": "4355400", "title": "Comparison of effects of paradoxical sleep deprivation and immobilization stress on 5-hydroxyindoleacetic acid in cerebrospinal fluid.", "content": "Comparison of effects of paradoxical sleep deprivation and immobilization stress on 5-hydroxyindoleacetic acid in cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355400"}
{"pmid": "4355401", "title": "Lyophilized combination pools of enterovirus equine antisera: preparation and test procedures for the identification of field strains of 42 enteroviruses.", "content": "Lyophilized combination pools of enterovirus equine antisera: preparation and test procedures for the identification of field strains of 42 enteroviruses. This paper describes the preparation of 8 dried pools (designated A to H) of sera. Each pool is composed of 10 or 11 of 42 individual enterovirus equine sera and contains 500 antibody units of each serum component per 0.1 ml. Procedures for using the antiserum pools are given, and guidance is provided for interpreting the results of serum neutralization tests in identifying field isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355401"}
{"pmid": "4355402", "title": "Immunological problems in leprosy research. 1.", "content": "Immunological problems in leprosy research. 1. This Memorandum reviews the present status of knowledge of the immunology of leprosy, with particular attention to developments since the publication of a similar review in 1970. The different types of lepromin reaction and their significance in healthy contacts and in patients with tuberculoid and lepromatous leprosy are discussed. The immunological responsiveness of patients with leprosy is also considered, with special attention to in vitro methods for evaluating this response. Part 2 of the Memorandum will cover possible mechanisms of altered immune response in leprosy (including a tentative scheme to explain the possible genesis of the lepromatous lesion); genetic, nutritional, and hormonal factors; the possibility of vaccination; attempts at immunotherapy; and areas in which further research is needed. A detailed protocol for evaluating the effect of transfer factor in leprosy will be included as an annex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355402"}
{"pmid": "4355407", "title": "Standard reference materials: standard quartz cuvettes for high-accuracy spectrophotometry.", "content": "Standard reference materials: standard quartz cuvettes for high-accuracy spectrophotometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355407"}
{"pmid": "4355409", "title": "Plasma retinol assay by elution from silicic acid with cymene (p-lsopropyl toluene).", "content": "Plasma retinol assay by elution from silicic acid with cymene (p-lsopropyl toluene).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355409"}
{"pmid": "4355408", "title": "Evaluation of a rapid latex-agglutination test for detection of alpha1-fetoprotein.", "content": "Evaluation of a rapid latex-agglutination test for detection of alpha1-fetoprotein. Detection of alpha-fetoprotein in adult sera has proved helpful in diagnosis of primary liver carcinoma;  detection of trace amounts in maternal sera during pregnancy can signal fetal distress and/or fetal death.  A latex-agglutination assay for alpha-fetoprotein (AFP) has been evaluated and compared to results from tests using counter-immunoelectrophoresis (CIEP).  In a series of 50 hepatoma patients, there was 88.6% agreement between the latex-agglutination assay method and the CIEP method.  No false positives were obtained in sera from 98 patients with other liver diseases or normal controls.  Both the latex and the CIEP tests must be performed on both undiluted and diluted sera to avoid prozone effects.  Simultaneous testing of samples with control latex for nonspecific rheumatoid-like agglutination is also necessary.  The latex method seems to be a simple, specific method of screening large numbers of sera for AFP;  all positive results should be confirmed by a control latex test and CIEP.  The method could be used for mass screening during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355408"}
{"pmid": "4355412", "title": "Separation of lipoprotein X and beta-lipoprotein by zonal centrifugation or hydroxyapatite chromatography.", "content": "Separation of lipoprotein X and beta-lipoprotein by zonal centrifugation or hydroxyapatite chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355412"}
{"pmid": "4355411", "title": "The effect of phospholipases on the release of enzymes from intact cells.", "content": "The effect of phospholipases on the release of enzymes from intact cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355411"}
{"pmid": "4355413", "title": "Entamoeba histolytica: concurrent irreversible loss of infectivity-pathogenicity and encystment potential after prolonged maintenance in axenic culture in vitro.", "content": "Entamoeba histolytica: concurrent irreversible loss of infectivity-pathogenicity and encystment potential after prolonged maintenance in axenic culture in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355413"}
{"pmid": "4355414", "title": "Microphallus pygmaeus: effect of long-acting ACTH preparation on establishment and retention in alimentary canal of the mouse.", "content": "Microphallus pygmaeus: effect of long-acting ACTH preparation on establishment and retention in alimentary canal of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355414"}
{"pmid": "4355415", "title": "Inhibition of phosphodiesterase by dihydroergotamine and hydergine in various organs of the cat in vitro.", "content": "Inhibition of phosphodiesterase by dihydroergotamine and hydergine in various organs of the cat in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355415"}
{"pmid": "4355416", "title": "Stimulation of transcription in HEp-2 cells by UV-inactivated poliovirus type 1.", "content": "Stimulation of transcription in HEp-2 cells by UV-inactivated poliovirus type 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355416"}
{"pmid": "4355417", "title": "Effect of colchicine on long lasting synaptic modifications induced by hyperactivity.", "content": "Effect of colchicine on long lasting synaptic modifications induced by hyperactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355417"}
{"pmid": "4355418", "title": "A study of the cytology and cell culture of the canine transmissible veneral sarcoma.", "content": "A study of the cytology and cell culture of the canine transmissible veneral sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355418"}
{"pmid": "4355419", "title": "The effect of kidney-bean leucoagglutinin on homograft rejection in mice.", "content": "The effect of kidney-bean leucoagglutinin on homograft rejection in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355419"}
{"pmid": "4355420", "title": "Herpes-virus and double-stranded RNA.", "content": "Herpes-virus and double-stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355420"}
{"pmid": "4355421", "title": "Effect of triparanol (mer 29) on rat liver lysosomes: cytochemical and biochemical study.", "content": "Effect of triparanol (mer 29) on rat liver lysosomes: cytochemical and biochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355421"}
{"pmid": "4355422", "title": "Effects of cyclic AMP and theophylline on mitogen-induced RNA synthesis in human peripheral blood lymphocytes.", "content": "Effects of cyclic AMP and theophylline on mitogen-induced RNA synthesis in human peripheral blood lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355422"}
{"pmid": "4355423", "title": "Fibrinolysis associated with oncogenic transformation. Requirement of plasminogen for correlated changes in cellular morphology, colony formation in agar, and cell migration.", "content": "Fibrinolysis associated with oncogenic transformation. Requirement of plasminogen for correlated changes in cellular morphology, colony formation in agar, and cell migration. Fetal bovine and dog serum were selectively freed of plasminogen by affinity chromatography. The resulting serum as well as native and reconstituted serum (obtained by the addition of purified plasminogen to the plasminogen-depleted serum) were used to examine the role of plasminogen in (a) growth of normal and SV-40-transformed hamster embryo fibroblasts in liquid medium, (b) growth of SV-40-transformed hamster embryo fibroblasts in soft agar, (c) aggregation - a characteristic morphological change of SV-40-transformed hamster cells, and (d) migration of SV-40-transformed and control 3T3 cells from a monolayer into a \"wound.\" The results demonstrated that exponential growth of both normal and transformed cells in liquid medium proceeded at the same rate in the presence or absence of plasminogen. In contrast, removal of plasminogen markedly depressed the plating efficiency of transformed cells in soft agar, eliminated their characteristic aggregation, and substantially reduced the extent of migration. The role of plasminogen and its activation in oncogenic transformation is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355423"}
{"pmid": "4355424", "title": "Evidence for a macrophage-mediated effect of poliovirus on the lymphocyte response to phytohemagglutinin.", "content": "Evidence for a macrophage-mediated effect of poliovirus on the lymphocyte response to phytohemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355424"}
{"pmid": "4355426", "title": "The role of phosphorus restriction in the prevention of secondary hyperparathyroidism in chronic renal disease.", "content": "The role of phosphorus restriction in the prevention of secondary hyperparathyroidism in chronic renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355426"}
{"pmid": "4355425", "title": "Role of humoral and cell-mediated immunity on the recovery of chickens from fowlpox virus infection.", "content": "Role of humoral and cell-mediated immunity on the recovery of chickens from fowlpox virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355425"}
{"pmid": "4355433", "title": "Effects of lysozyme on normal and transformed mammalian cells.", "content": "Effects of lysozyme on normal and transformed mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355433"}
{"pmid": "4355427", "title": "Letter: Comments on \"The administration of chiropractic in the New York City Medicaid program\".", "content": "Letter: Comments on \"The administration of chiropractic in the New York City Medicaid program\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355427"}
{"pmid": "4355434", "title": "Influence of cyclic AMP on early events of the immune induction.", "content": "Influence of cyclic AMP on early events of the immune induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355434"}
{"pmid": "4355428", "title": "Should a paper on the administration of chiropractic have been published in Medical Care? With comments on derivative questions.", "content": "Should a paper on the administration of chiropractic have been published in Medical Care? With comments on derivative questions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355428"}
{"pmid": "4355435", "title": "New bioassay for luteinizing hormone.", "content": "New bioassay for luteinizing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355435"}
{"pmid": "4355438", "title": "Proton magnetic resonance and the composition of proteins.", "content": "Proton magnetic resonance and the composition of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355438"}
{"pmid": "4355436", "title": "Changes in distribution of electric charges in the surface membrane of rat ascites hepatocarcinoma cells induced by con A.", "content": "Changes in distribution of electric charges in the surface membrane of rat ascites hepatocarcinoma cells induced by con A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355436"}
{"pmid": "4355439", "title": "Delta 9-tetrahydrocannabinol and the sleep-wakefulness cycle in rabbits.", "content": "Delta 9-tetrahydrocannabinol and the sleep-wakefulness cycle in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355439"}
{"pmid": "4355440", "title": "Sleep patterns in the owl Strix aluco.", "content": "Sleep patterns in the owl Strix aluco.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355440"}
{"pmid": "4355441", "title": "The relationship between the antidiuretic activity of rat eye plexus blood and passive avoidance behaviour.", "content": "The relationship between the antidiuretic activity of rat eye plexus blood and passive avoidance behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355441"}
{"pmid": "4355443", "title": "Amebiasis: newer methods of diagnosis and treatment.", "content": "Amebiasis: newer methods of diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355443"}
{"pmid": "4355442", "title": "Esophagogastric substitution after total gastrectomy and distal esophagectomy for locally advanced gastric cancer.", "content": "Esophagogastric substitution after total gastrectomy and distal esophagectomy for locally advanced gastric cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355442"}
{"pmid": "4355445", "title": "Oxandrolone and human growth hormone. Comparison of growth-stimulating effects in short children.", "content": "Oxandrolone and human growth hormone. Comparison of growth-stimulating effects in short children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355445"}
{"pmid": "4355444", "title": "Studies on cartilage formation. XV. Enzyme histochemical investigation on Krebs cycle, terminal oxidation and hexose monophosphate shunt.", "content": "Studies on cartilage formation. XV. Enzyme histochemical investigation on Krebs cycle, terminal oxidation and hexose monophosphate shunt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355444"}
{"pmid": "4355446", "title": "Cause of acute hemorrhagic cystitis in children.", "content": "Cause of acute hemorrhagic cystitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355446"}
{"pmid": "4355447", "title": "Chronic idiopathic hyperphosphatasia in an Indian child.", "content": "Chronic idiopathic hyperphosphatasia in an Indian child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355447"}
{"pmid": "4355448", "title": "Oral-facial dyskinesia and quadriplegia associated with poliomyelitis virus type 3.", "content": "Oral-facial dyskinesia and quadriplegia associated with poliomyelitis virus type 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355448"}
{"pmid": "4355449", "title": "Metastatic carcinoma to the pancreas. Another cause for acute pancreatitis.", "content": "Metastatic carcinoma to the pancreas. Another cause for acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355449"}
{"pmid": "4355450", "title": "Neighborhood Extension of Activity Therapy.", "content": "Neighborhood Extension of Activity Therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355450"}
{"pmid": "4355452", "title": "Avian cardiac receptors: activity changes by blood pressure, carbon dioxide, and pH.", "content": "Avian cardiac receptors: activity changes by blood pressure, carbon dioxide, and pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355452"}
{"pmid": "4355451", "title": "Cardiac afferent activity in depressor nerve of the chicken.", "content": "Cardiac afferent activity in depressor nerve of the chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355451"}
{"pmid": "4355453", "title": "Electrical discharge of single enteric neurons of guinea pig small intestine.", "content": "Electrical discharge of single enteric neurons of guinea pig small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355453"}
{"pmid": "4355454", "title": "Effects of angiotensin I and angiotensin II on hindlimb and coronary vascular resistance.", "content": "Effects of angiotensin I and angiotensin II on hindlimb and coronary vascular resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355454"}
{"pmid": "4355455", "title": "Blast transformation of lymphocytes in amebiasis.", "content": "Blast transformation of lymphocytes in amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355455"}
{"pmid": "4355456", "title": "Epidemiology of the acute fevers of unknown origin in South Vietnam: effect of laboratory support upon clinical diagnosis.", "content": "Epidemiology of the acute fevers of unknown origin in South Vietnam: effect of laboratory support upon clinical diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355456"}
{"pmid": "4355457", "title": "Prostaglandins and the lung.", "content": "Prostaglandins and the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355457"}
{"pmid": "4355458", "title": "Comparison of serum lipid and lipoprotein profiles of tuberculin-positive and tuberculin-negative monkeys (Macaca sp).", "content": "Comparison of serum lipid and lipoprotein profiles of tuberculin-positive and tuberculin-negative monkeys (Macaca sp).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355458"}
{"pmid": "4355462", "title": "Letter: Herpes simplex of penis and anus.", "content": "Letter: Herpes simplex of penis and anus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355462"}
{"pmid": "4355464", "title": "Chemodectomas of the middle ear. A comparison of therapeutic modalities.", "content": "Chemodectomas of the middle ear. A comparison of therapeutic modalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355464"}
{"pmid": "4355465", "title": "Comparative biochemical study of otosclerosis and osteogenesis imperfecta.", "content": "Comparative biochemical study of otosclerosis and osteogenesis imperfecta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355465"}
{"pmid": "4355466", "title": "Isolation and characterization of surface membranes from chorioallantoic cells and chick fibroblasts.", "content": "Isolation and characterization of surface membranes from chorioallantoic cells and chick fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355466"}
{"pmid": "4355467", "title": "ATPase in isolated membranes of Bacillus subtilis.", "content": "ATPase in isolated membranes of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355467"}
{"pmid": "4355469", "title": "Letter: Methyldopa and depression.", "content": "Letter: Methyldopa and depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355469"}
{"pmid": "4355468", "title": "Suramin: a potent ATPase inhibitor which acts on the inside surface of the sodium pump.", "content": "Suramin: a potent ATPase inhibitor which acts on the inside surface of the sodium pump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355468"}
{"pmid": "4355470", "title": "A three year comparison of acute respiratory disease, shrink and weight gain in preconditioned and non-preconditioned Illinois beef calves sold at the same auction and mixed in a feedlot.", "content": "A three year comparison of acute respiratory disease, shrink and weight gain in preconditioned and non-preconditioned Illinois beef calves sold at the same auction and mixed in a feedlot. During 1969 to 1971, 78 preconditioned (PC) and 79 non-preconditioned (NPC) beef calves were purchased at the same auction and mixed in a feedlot. Preconditioned calves were weaned 30 days before the sale, used to drinking from a tank, and vaccinated against blackleg, malignant edema, infectious bovine rhinotracheitis (IBR), parainfluenza-3 (PI3) and bovine virus diarrhea (BVD) in 1970 and 1971, and Pasteurella hemolytica and multocida in 1971. All vaccinations were completed two to three weeks before the sale. PC calves were given thiabenzadole. PC calves had significantly less shrink after shipment and in 1971 significantly more rapid daily gain during the first weeks of the feeding period. In 1969 more PC calves were treated for acute respiratory disease than NPC calves during an outbreak of PI3 and BVD infection. In 1970 and 1971 fewer PC than NPC calves were treated for acute respiratory tract disease during outbreaks of PI3 infection. The differences in clinical respiratory disease were significant in 1971. Inclusion of two doses of P. hemolytica and P. multocida bacterin before the sale in 1971 and use of an intranasal PI3 vaccine was considered to improve the PC program. Fecal egg counts for gastrointestinal nematodes were much lower in PC calves treated with thiabenzadole than untreated NPC calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355470"}
{"pmid": "4355471", "title": "Necrotic enteritis in broiler chickens. I. A review of the literature and the prevalence of the disease in Ontario.", "content": "Necrotic enteritis in broiler chickens. I. A review of the literature and the prevalence of the disease in Ontario. The available literature on necrotic enteritis in broiler chickens is reviewed. The records of three poultry diagnostic laboratories in Ontario were examined for the years 1969, 1970 and 1971. During this period 855 (7.7%) of 11,076 consignments of broiler chickens examined were diagnosed as necrotic enteritis. The condition was most common in broilers at three weeks of age, with 66% of all cases occurring in chickens between two and four and one half weeks. The disease occurred throughout the year but it was most common during July, August, September and October. Necrotic enteritis often occurred more than once per year on a farm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355471"}
{"pmid": "4355472", "title": "Vesicular lesions produced in guinea pigs by a Staphylococcus aureus strain.", "content": "Vesicular lesions produced in guinea pigs by a Staphylococcus aureus strain. A bacterium isolated from vesicular lesions on foot pads of guinea pigs reproduced lesions similar to those seen in experimental infections of guinea pigs with foot-and-mouth disease virus. (FMDV). These bacterial lesions were produced with an inactivated FMDV suspension. Identification as Staphylococcus aureus was determined by growth characteristics on nutrient and blood agar, Gram staining, fermentation of mannitol and coagulase positive reactions. In addition, the organism was sensitive to concentrations of penicillin and streptomycin commonly used in laboratory diluents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355472"}
{"pmid": "4355474", "title": "Serum glycoproteins in hyperlipoproteinemic patients with and without clinical vascular disease.", "content": "Serum glycoproteins in hyperlipoproteinemic patients with and without clinical vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355474"}
{"pmid": "4355475", "title": "The excretion of adenosine 3',5'-cyclic monophosphate by children with burns.", "content": "The excretion of adenosine 3',5'-cyclic monophosphate by children with burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355475"}
{"pmid": "4355473", "title": "Catabolism of cholesterol in hypercholesterolemia and its relationship to plasma triglycerides.", "content": "Catabolism of cholesterol in hypercholesterolemia and its relationship to plasma triglycerides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355473"}
{"pmid": "4355476", "title": "Effect of exposure to quartz dust in vivo on pentose cycle activity in guinea pig lung.", "content": "Effect of exposure to quartz dust in vivo on pentose cycle activity in guinea pig lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355476"}
{"pmid": "4355477", "title": "Induction of 3T3 cell division at the monolayer stage. Early changes in macromolecular processes.", "content": "Induction of 3T3 cell division at the monolayer stage. Early changes in macromolecular processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355477"}
{"pmid": "4355478", "title": "A radioautographic method for the localization of steroid ligands and receptors by cell affinity labelling.", "content": "A radioautographic method for the localization of steroid ligands and receptors by cell affinity labelling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355478"}
{"pmid": "4355479", "title": "Effects of N6-monobutyryl-cyclic AMP on glutamate decarboxylase activity in fetal rat brain cells and glial tumor cells in culture.", "content": "Effects of N6-monobutyryl-cyclic AMP on glutamate decarboxylase activity in fetal rat brain cells and glial tumor cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355479"}
{"pmid": "4355480", "title": "Temperature sensitive cells in the study of SV40 lysis versus SV40 transformation.", "content": "Temperature sensitive cells in the study of SV40 lysis versus SV40 transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355480"}
{"pmid": "4355481", "title": "Subcellular localization of the leucine biosynthetic enzymes in yeast.", "content": "Subcellular localization of the leucine biosynthetic enzymes in yeast. When baker's yeast spheroplasts were lysed by mild osmotic shock, practically all of the isopropylmalate isomerase and the beta-isopropylmalate dehydrogenase was released into the 30,000 x g supernatant fraction, as was the cytosol marker enzyme, glucose-6-phosphate dehydrogenase. alpha-Isopropylmalate synthase, however, was not detected in the initial supernatant, but could be progressively solubilized by homogenization, appearing more slowly than citrate synthase but faster than cytochrome oxidase. Of the total glutamate-alpha-ketoisocaproate transaminase activity, approximately 20% was in the initial soluble fraction, whereas solubilization of the remainder again required homogenization of the spheroplast lysate. Results from sucrose density gradient centrifugation of a cell-free particulate fraction and comparison with marker enzymes suggested that alpha-isopropylmalate synthase was located in the mitochondria. It thus appears that, in yeast, the first specific enzyme in the leucine biosynthetic pathway (alpha-isopropylmalate synthase) is particulate, whereas the next two enzymes in the pathway (isopropylmalate isomerase and beta-isopropylmalate dehydrogenase) are \"soluble,\" with glutamate-alpha-ketoisocaproate transaminase activity being located in both the cytosol and particulate cell fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355481"}
{"pmid": "4355483", "title": "Purification and properties of Lactobacillus plantarum inducible malic enzyme.", "content": "Purification and properties of Lactobacillus plantarum inducible malic enzyme. Inducible malic enzyme (l-malate:NAD oxidoreductase [decarboxylating], EC 1.1.1.39) was isolated from Lactobacillus plantarum and purified about 100-fold with 27% yield of the original activity. Kinetic studies with the purified malic enzyme yielded the following results: pH optimum, 7.6 to 8.0; K(m) for l-malate, 0.38 mM; K(m) for NAD, 0.072 mM; and K(m) for MnCl(2), 0.048 mM. It was shown that this enzyme was inhibited by high concentrations of substrate and nicotinamide adenine dinucleotide (NAD), indicating it may be regulated by substrate or NAD. Molecular weight of 130,000 +/- 10,000 was determined by Sephadex gel filtration and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The isoelectric point, determined by isoelectrofocusing, was 4.3 at 7 C. Isoelectrofocusing also resolved three active peaks which focused at pH 4.19, 4.31, and 4.40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355483"}
{"pmid": "4355482", "title": "Isolation and characterization of two protease-producing mutants from Staphylococcus aureus.", "content": "Isolation and characterization of two protease-producing mutants from Staphylococcus aureus. Two mutants with increased protease production were isolated after nitrosoguanidine treatment of Staphylococcus aureus 8325N. The wild type produces low amounts of extracellular proteolytic activity. The enzyme was inducible and could only be detected if casein or preferably skim milk powder was used as inducer. The optimal pH, salt concentration, and media for enzyme production were determined. The mutants differed from the wild type in several phenotypic characters. The pattern of extracellular deoxyribonuclease and alkaline phosphatase differed between the mutants and the wild type. Several carbohydrates such as lactose, galactose, and mannitol were not utilized by the mutants, probably owing to a block in the uptake. Glucose could, however, be utilized by the mutants. Reversion frequency to wild type with regard to carbohydrate utilization was spontaneously high, and all revertants regained the parental pattern irrespective of the carbohydrate used for selection. The results suggest that a single locus may control the excretion of extracellular enzymes and carbohydrate uptake in S. aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355482"}
{"pmid": "4355485", "title": "Sensitization by ethylenediaminetetraacetate of Clostridium perfringens type A spores to germination by lysozyme.", "content": "Sensitization by ethylenediaminetetraacetate of Clostridium perfringens type A spores to germination by lysozyme. Clostridium perfringens spores (three strains) were normally resistant to germination by lysozyme. In the absence of disulfide bond-breaking reagents, tetrasodium ethylenediaminetetraacetate rapidly sensitized the spores to lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355485"}
{"pmid": "4355484", "title": "Pyrimidine metabolism in Acinetobacter calcoaceticus.", "content": "Pyrimidine metabolism in Acinetobacter calcoaceticus. The metabolism of thymine, thymidine, uracil, and uridine has been investigated in five different strains of Acinetobacter calcoaceticus. Attempts to isolate thymine and thymidine auxotrophic mutants were not successful. Consistent with this finding was the observation that uptake of radioactive thymine or thymidine could not be demonstrated. Search for enzymes capable of transforming thymine via thymidine to thymidine-5'-monophosphate in crude extracts was performed, and the following enzymes were absent judging from enzyme assays: thymidine phosphorylase (EC 2.4.2.4), trans-N-deoxyribosylase (EC 2.4.2.6), and thymidine kinase (EC 2.7.1.21). The enzymes responsible for the phosphorylation of thymidine-5'-monophosphate to thymidine-5'-triphosphate were present in crude extracts. Radioactive uracil was readily incorporated into both ribonucleic acid and deoxyribonucleic acid, the ratio being 6:1, and radioactivity was found only in pyrimidine bases. No uptake of uridine could be demonstrated. Uridine-5'-monophosphate pyrophosphorylase (EC 2.4.2.9) activity was detected in crude extracts, suggesting that uracil is converted directly to uridine-5'-monophosphate which is then phosphorylated to uridine-5'-triphosphate or transformed to other ribo- and deoxypyrimidine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355484"}
{"pmid": "4355486", "title": "Isolation and characterization of a mutant of Salmonella typhimurium deficient in a major deoxyribonucleic acid polymerase activity.", "content": "Isolation and characterization of a mutant of Salmonella typhimurium deficient in a major deoxyribonucleic acid polymerase activity. A mutant of Salmonella typhimurium strain LT2 that is deficient in a major deoxyribonucleic acid (DNA) polymerase activity has been isolated and characterized. This mutant resembles the pol mutants of E. coli in that it has low DNA polymerase activity and it is sensitive to methyl methane sulfonate as well as ultraviolet irradiation. Revertants selected for methyl methane sulfonate resistance are no longer sensitive to ultraviolet irradiation and contain normal DNA polymerase levels. No direct role in replication can be ascribed to this polymerase activity since cells grow well in its absence. In addition, the LT2 plasmid has been shown to exist in the mutant strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355486"}
{"pmid": "4355488", "title": "Trehalose metabolism in germinating spores of Streptomyces hygroscopicus.", "content": "Trehalose metabolism in germinating spores of Streptomyces hygroscopicus. Evidence is presented which indicates that utilization of trehalose is an early event in spore germination in Streptomyces hygroscopicus. Early in spore germination and before any increase in cell mass, the activity of trehalase increased more than 15-fold, while the intracellular content of trehalose fell to very low levels. On the other hand, increased activity of the trehalose phosphate synthetase or disappearance of glycogen did not occur until later in germination, during which time cell mass was also increasing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355488"}
{"pmid": "4355487", "title": "Evidence for proteolytic degradation of histidinol phosphate phosphatase specified by nonsense mutants of the hisB gene of Salmonella typhimurium.", "content": "Evidence for proteolytic degradation of histidinol phosphate phosphatase specified by nonsense mutants of the hisB gene of Salmonella typhimurium. The gene products from hisB nonsense mutants having histidinol phosphate phosphatase activity were isolated from Salmonella typhimurium. The enzyme from strain TR691 (hisB278 hisT1529 aroD5) was isolated in the presence of diisopropylfluorophosphate. Three electrophoretically separable forms were demonstrated, and all were shown to have a mol wt of approximately 38,000 and to consist of a single polypeptide chain. Previously, two forms of the phosphatase enzyme from this strain were isolated without diisopropylfluorophosphate and shown to have a different subunit composition. Strain TA387 (hisB2133 his 01242) was shown to have two electrophoretically separable phosphatases with a mol wt of about 52,000 and consisted of 17,000- to 19,000-mol wt polypeptide chains as evidenced by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. The results could be explained by proteolytic cleavage of the primary gene product which can partially be prevented by the protease inhibitor. Strain TA387 phosphatase lost all activity in 8 M urea but could be renatured by dialysis. Gel filtration showed that it also regained its original molecular weight. The values of K(m) of histidinol phosphate and the competition inhibition constant for histidinol were determined. The addition of MnCl(2) to the assay was shown to shift the optimal pH value to a lower pH value.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355487"}
{"pmid": "4355489", "title": "Altered mitochondrial respiration in a chromosomal mutant of Neurospora crassa.", "content": "Altered mitochondrial respiration in a chromosomal mutant of Neurospora crassa. A mutant of Neurospora crassa (cni-1) has been isolated that has two pathways of mitochondrial respiration. One pathway is sensitive to cyanide and antimycin A, the other is sensitive only to salicyl hydroxamic acid. Respiration can proceed through either pathway and both pathways together in this mutant account for greater than 90% of all mitochondrial respiration. The cni-1 mutation segregates as a nuclear gene in crosses to other strains of Neurospora. Absorption spectra of isolated mitochondria from cni-1 show typical b- and c-type cytochromes but the absorption peaks corresponding to cytochrome aa(3) are not detectable. Extraction of soluble cytochrome c-546 from these mitochondria followed by reduction with ascorbate reveals a new absorption peak at 426 nm that is not present in wild-type mitochondria. This peak may be due to an altered cytochrome oxidase with abnormal spectral properties. Mitochondria from cni-1 have elevated levels of succinate-cytochrome c reductase but reduced levels of nicotinamide adenine dinucleotide reduced form cytochrome c reductase and of cyanide- and azide-sensitive cytochrome c oxidase. These studies suggest that the cni-1 mutation results in the abnormal assembly of cytochrome c oxidase so that the typical cytochrome aa(3) spectrum is lost and the enzyme activity is reduced. As a consequence of this alteration, a cyanide-insensitive respiratory pathway is elaborated by these mitochondria which may serve to stimulate adenosine 5'-triphosphate production via substrate level phosphorylation by glycolysis and the Krebs cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355489"}
{"pmid": "4355490", "title": "Purification and properties of cytoplasmic and mitochondrial malate dehydrogenases of Physarum polycephalum.", "content": "Purification and properties of cytoplasmic and mitochondrial malate dehydrogenases of Physarum polycephalum. Two isoenzymes of malate dehydrogenase (MDH) were demonstrated in plasmodia of Physarum polycephalum by polyacrylamide-gel electrophoresis. The more \"cathodal\" form was uniquely associated with mitochondria (M-MDH) and the other form was found in the soluble cytoplasm (S-MDH). The isoenzymes were separated by acetone fractionation of soluble plasmodial homogenates acidified to pH 5.0. The M-MDH was purified 201-fold by cetylpyridinium chloride treatment, fractionation with ammonium sulfate, gradient elution from sulfoethyl cellulose at pH 6.0, and Sephadex G-100 chromatography. The S-MDH was purified 155-fold by ammonium sulfate fractionation, diethylaminoethyl cellulose chromatography, gradient elution from sulfoethyl cellulose at pH 5.5, and Sephadex G-100 chromatography. The optimal cis-oxalacetate concentrations were 0.35 mM for M-MDH and 0.25 mM for S-MDH, and the optimal pH for both isoenzymes was 7.6 for oxalacetate reduction. The optimal l-malate concentrations were 5 mM for S-MDH and 6 mM for M-MDH, and both isoenzymes exhibited an optimal pH of 10.0 for L-malate oxidation. The Michaelis constants of S-MDH and M-MDH served to discriminate between the isoenzymes. The S-MDH was more heat-stable than the M-MDH. High concentrations of oxalacetate and malate inhibited S-MDH more than M-MDH. The isoenzymes were further distinguished by their utilization of analogues of nicotinamide adenine dinucleotide. Many properties of the Physarum isoenzymes were similar to those of more complex organisms, especially vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355490"}
{"pmid": "4355491", "title": "Cyclic 3',5'-adenosine monophosphate phosphodiesterase of Escherichia coli.", "content": "Cyclic 3',5'-adenosine monophosphate phosphodiesterase of Escherichia coli. The cyclic 3',5'-adenosine monophosphate (c-AMP) phosphodiesterase from Escherichia coli has been partially purified. The enzyme has an apparent molecular weight of 30,000, a Michaelis constant of 0.5 mM c-AMP, and a pH optimum of 7. The partially purified enzyme requires for activity the presence of a reducing compound and of either iron or a protein which seemingly acts as iron carrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355491"}
{"pmid": "4355494", "title": "Ascorbate oxidase. Spectral characteristics of the enzyme.", "content": "Ascorbate oxidase. Spectral characteristics of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355494"}
{"pmid": "4355493", "title": "Ultrastructural aspects of a mutant of Schizophyllum commune with continuous nuclear migration.", "content": "Ultrastructural aspects of a mutant of Schizophyllum commune with continuous nuclear migration. Study of a mutant of the basidomycete Schizophyllum commune with continuous migration of nuclei revealed that the mutant is characterized by vacuolization, bundles of fibrillar-like material, and microtubules. The bundles of fibrillar-like material and microtubules extend through degraded septa to adjacent cells and are found in proximity to nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355493"}
{"pmid": "4355492", "title": "Mutants of Escherichia coli K-12 \"cryptic,\" or deficient in 5'-nucleotidase (uridine diphosphate-sugar hydrolase) and 3'-nucleotidase (cyclic phosphodiesterase) activity.", "content": "Mutants of Escherichia coli K-12 \"cryptic,\" or deficient in 5'-nucleotidase (uridine diphosphate-sugar hydrolase) and 3'-nucleotidase (cyclic phosphodiesterase) activity. Mutants of Escherichia coli have been selected for the absence of 5'-nucleotidase (uridine diphosphate-sugar hydrolase) and 3'-nucleotidase (2',3'-cyclic phophodiesterase). Mutants selected for the absence of 5'-nucleotidase are of two kinds: those that lack detectable activity for the enzyme (Ush(-)), and those that possess activity when cell extracts are assayed, but not when intact cells are assayed (cryptic; Crp(-)). The latter class is probably identical to a type of mutant previously reported by Ward and Glaser. When mutants are selected for the absence of 3'-nucleotidase, Crp(-)mutants are also obtained. Thus far, however, mutants totally lacking this enzyme have not been found. The location on the genetic map of one ush mutation is at position 11 min and that of one crp mutation at approximately 67 min. In the crp mutant, 5'-nucleotidase and 3'-nucleotidase remain located in the periplasm. This mutant is also cryptic for alkaline phosphatase but not for acid hexose phosphatase. Treatment of cells with ethylenediamine-tetraacetate substantially alleviated crypticity. These data are discussed in terms of the organization of periplasmic enzymes and of the outer membrane as a permeability barrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355492"}
{"pmid": "4355495", "title": "Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. I. Responses to catecholamines in parental and hybrid cells.", "content": "Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. I. Responses to catecholamines in parental and hybrid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355495"}
{"pmid": "4355496", "title": "Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. II. Effects of prostaglandin E1 and theophylline on parental and hybrid cells.", "content": "Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. II. Effects of prostaglandin E1 and theophylline on parental and hybrid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355496"}
{"pmid": "4355497", "title": "Cu (II)-carbon bonding in cyanide complexes of copper enzymes. 13C splitting of the Cu(II) electron spin resonance.", "content": "Cu (II)-carbon bonding in cyanide complexes of copper enzymes. 13C splitting of the Cu(II) electron spin resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355497"}
{"pmid": "4355498", "title": "High spin and low spin forms of Co(II) carbonic anhydrase. Temperature-dependent changes in spin state and coordination geometry.", "content": "High spin and low spin forms of Co(II) carbonic anhydrase. Temperature-dependent changes in spin state and coordination geometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355498"}
{"pmid": "4355500", "title": "The nucleotide sequence of a serine transfer ribonucleic acid from Escherichia coli.", "content": "The nucleotide sequence of a serine transfer ribonucleic acid from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355500"}
{"pmid": "4355499", "title": "Studies on T3-induced ribonucleic acid polymerase. 3. Purification and characterization of the T3-induced ribonucleic acid polymerase from bacteriophage T3-infected Escherichia coli cells.", "content": "Studies on T3-induced ribonucleic acid polymerase. 3. Purification and characterization of the T3-induced ribonucleic acid polymerase from bacteriophage T3-infected Escherichia coli cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355499"}
{"pmid": "4355501", "title": "Capacity for steroidogenesis of adrenals in hypophysectomized and adrenocorticotropic hormone-treated hypophysectomized rats. Implication of a ribonucleic acid for hormone-induced steroidogenesis.", "content": "Capacity for steroidogenesis of adrenals in hypophysectomized and adrenocorticotropic hormone-treated hypophysectomized rats. Implication of a ribonucleic acid for hormone-induced steroidogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355501"}
{"pmid": "4355502", "title": "Comparison of the effects of adrenocorticotropic hormone on the steroidogenic activity and ultrastructure of adrenal cortex.", "content": "Comparison of the effects of adrenocorticotropic hormone on the steroidogenic activity and ultrastructure of adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355502"}
{"pmid": "4355503", "title": "1,24,25-Trihydroxyvitamin D3. A metabolite of vitamin D3 effective on intestine.", "content": "1,24,25-Trihydroxyvitamin D3. A metabolite of vitamin D3 effective on intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355503"}
{"pmid": "4355504", "title": "Chemical synthesis of delta 7,24-(3alpha-3H)cholestadien-3beta-ol and its conversion to cholesterol in the rat.", "content": "Chemical synthesis of delta 7,24-(3alpha-3H)cholestadien-3beta-ol and its conversion to cholesterol in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355504"}
{"pmid": "4355505", "title": "Positional specificity of purified milk lipoprotein lipase.", "content": "Positional specificity of purified milk lipoprotein lipase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355505"}
{"pmid": "4355506", "title": "The variety of intraspecific misacylations carried out by isoleucyl transfer ribonucleic acid synthetase of Escherichia coli.", "content": "The variety of intraspecific misacylations carried out by isoleucyl transfer ribonucleic acid synthetase of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355506"}
{"pmid": "4355507", "title": "A role for the microtubular system in the release of very low density lipoproteins by perfused mouse livers.", "content": "A role for the microtubular system in the release of very low density lipoproteins by perfused mouse livers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355507"}
{"pmid": "4355509", "title": "Synthesis and antiviral activity of homologs of noformycin.", "content": "Synthesis and antiviral activity of homologs of noformycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355509"}
{"pmid": "4355508", "title": "Control of steroidogenesis in pre-ovulatory cells. Luteinizing hormone stimulation of (14C)-acetate incorporation into sterols.", "content": "Control of steroidogenesis in pre-ovulatory cells. Luteinizing hormone stimulation of (14C)-acetate incorporation into sterols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355508"}
{"pmid": "4355510", "title": "Angiotensin II. Synthesis and biological activity of 6-(1-methylhistidine) and 6-(3-methylhistidine) analogs.", "content": "Angiotensin II. Synthesis and biological activity of 6-(1-methylhistidine) and 6-(3-methylhistidine) analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355510"}
{"pmid": "4355511", "title": "Effect of dietary protein and magnesium on selected ATP phosphotransferases and neuromuscular behavior in young rats.", "content": "Effect of dietary protein and magnesium on selected ATP phosphotransferases and neuromuscular behavior in young rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355511"}
{"pmid": "4355512", "title": "Occult carcinoma of second breast following mastectomy.", "content": "Occult carcinoma of second breast following mastectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355512"}
{"pmid": "4355514", "title": "Phospholipids and calcium uptake in experimental tumors.", "content": "Phospholipids and calcium uptake in experimental tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355514"}
{"pmid": "4355515", "title": "Effects of dibutyryl cyclic AMP and related compounds on newt limb regeneration blastemas in vitro. I. 3H-thymidine incorporation.", "content": "Effects of dibutyryl cyclic AMP and related compounds on newt limb regeneration blastemas in vitro. I. 3H-thymidine incorporation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355515"}
{"pmid": "4355516", "title": "Effects of dibutyryl cyclic AMP and related compounds on newt limb regeneration blastemas in vitro. II. 14C-leucine incorporation.", "content": "Effects of dibutyryl cyclic AMP and related compounds on newt limb regeneration blastemas in vitro. II. 14C-leucine incorporation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355516"}
{"pmid": "4355517", "title": "Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics.", "content": "Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355517"}
{"pmid": "4355518", "title": "Neural processes in thermoregulation.", "content": "Neural processes in thermoregulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355518"}
{"pmid": "4355522", "title": "Amoebic infection of the female genital tract. A report of three cases.", "content": "Amoebic infection of the female genital tract. A report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355522"}
{"pmid": "4355523", "title": "Phosphorylation of muscle membranes: identification of a membrane-bound protein kinase.", "content": "Phosphorylation of muscle membranes: identification of a membrane-bound protein kinase. A membrane-bound protein kinase occurs in membranes derived from rat skeletal muscle and appears limited to a surface membrane fraction. The enzyme is magnesium dependent, is only minimally stimulated by cyclic nucleotides, and phosphorylates serine and to a lesser extent threonine residues of three membrane proteins with molecular weights of less than 30,000.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355523"}
{"pmid": "4355525", "title": "Pancreatitis and hyperlipoproteinemia.", "content": "Pancreatitis and hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355525"}
{"pmid": "4355524", "title": "Oscillation of cyclic adenosine monophosphate concentration during the myocardial contraction cycle.", "content": "Oscillation of cyclic adenosine monophosphate concentration during the myocardial contraction cycle. The concentration of adenosine 3',5'-monophosphate (cyclic AMP) rises and falls during each myocardial contraction cycle. Peak concentrations of cyclic AMP precede peak development of systolic tension. Epinephrine alters the normal oscillation in myocardial cyclic AMP and increases both diastolic and systolic concentrations of the cyclic nucleotide. These transient changes in myocardial cyclic AMP indicate a potential role for cyclic AMP as a beat-to-beat regulator of myocardial contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355524"}
{"pmid": "4355526", "title": "Differences in the response of normal and transformed BHK21 cells to dual virus infection. Conditions affecting synergism between vesicular stomatitis virus and newcastle disease virus.", "content": "Differences in the response of normal and transformed BHK21 cells to dual virus infection. Conditions affecting synergism between vesicular stomatitis virus and newcastle disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355526"}
{"pmid": "4355527", "title": "Presence of antigen common to avian tumor viral envelope antigen in normal chick embryo cells.", "content": "Presence of antigen common to avian tumor viral envelope antigen in normal chick embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355527"}
{"pmid": "4355529", "title": "Protein metabolism in SV40-infected cells.", "content": "Protein metabolism in SV40-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355529"}
{"pmid": "4355530", "title": "Specificity of TMV RNA encapsidation: in vitro coating of heterologous RNA by TMV protein.", "content": "Specificity of TMV RNA encapsidation: in vitro coating of heterologous RNA by TMV protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355530"}
{"pmid": "4355528", "title": "Evidence for helper independent murine sarcoma virus. I. Segregation of replication-defective and transformation-defective viruses.", "content": "Evidence for helper independent murine sarcoma virus. I. Segregation of replication-defective and transformation-defective viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355528"}
{"pmid": "4355531", "title": "Effects of omentumectomy on production of endotoxin-type interferon in mice.", "content": "Effects of omentumectomy on production of endotoxin-type interferon in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355531"}
{"pmid": "4355532", "title": "Diffusion coefficients and hydrodynamic radii of three spherical RNA viruses by laser light scattering.", "content": "Diffusion coefficients and hydrodynamic radii of three spherical RNA viruses by laser light scattering.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355532"}
{"pmid": "4355533", "title": "Differential expression of transformation in rat and chicken cells infected with an avian sarcoma virus ts mutant.", "content": "Differential expression of transformation in rat and chicken cells infected with an avian sarcoma virus ts mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355533"}
{"pmid": "4355534", "title": "Effects of dibutyryl-cAMP on adenovirus replication in different cell lines.", "content": "Effects of dibutyryl-cAMP on adenovirus replication in different cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355534"}
{"pmid": "4355535", "title": "Synthesis of complementary RNA by poliovirus polymerase in vitro.", "content": "Synthesis of complementary RNA by poliovirus polymerase in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355535"}
{"pmid": "4355536", "title": "Size of gene sequences shared by polioviruses types 1, 2, and 3.", "content": "Size of gene sequences shared by polioviruses types 1, 2, and 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355536"}
{"pmid": "4355537", "title": "Analysis of the inhibition of the ACTH release by hypothalamic implants of atropine.", "content": "Analysis of the inhibition of the ACTH release by hypothalamic implants of atropine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355537"}
{"pmid": "4355538", "title": "Stimulation of ornithine decarboxylase and nuclear RNA polymerase activity in rat liver by glucagon and dibutyryl cyclic amp.", "content": "Stimulation of ornithine decarboxylase and nuclear RNA polymerase activity in rat liver by glucagon and dibutyryl cyclic amp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355538"}
{"pmid": "4355539", "title": "Effect of D2O and nicotinamide adenine dinucleotide on the sedimentation properties and structure of glyceraldehyde phosphate dehydrogenase.", "content": "Effect of D2O and nicotinamide adenine dinucleotide on the sedimentation properties and structure of glyceraldehyde phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355539"}
{"pmid": "4355541", "title": "Nuclear magnetic resonance studies of the interaction of valinomycin with unsonicated lecithin bilayers.", "content": "Nuclear magnetic resonance studies of the interaction of valinomycin with unsonicated lecithin bilayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355541"}
{"pmid": "4355540", "title": "Isolation and characterization of the cyanogen bromide fragments from the high-density apolipoprotein glutamine I.", "content": "Isolation and characterization of the cyanogen bromide fragments from the high-density apolipoprotein glutamine I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355540"}
{"pmid": "4355543", "title": "Functional arginyl residues in carboxypeptidase A. Modification with butanedione.", "content": "Functional arginyl residues in carboxypeptidase A. Modification with butanedione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355543"}
{"pmid": "4355542", "title": "Competitive inhibitors of renin.", "content": "Competitive inhibitors of renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355542"}
{"pmid": "4355544", "title": "Interaction of actin with analogs of adenosine triphosphate.", "content": "Interaction of actin with analogs of adenosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355544"}
{"pmid": "4355546", "title": "Properties of tRNALys4 from various tissues.", "content": "Properties of tRNALys4 from various tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355546"}
{"pmid": "4355545", "title": "Correlation between a specific isoaccepting lysyl transfer ribonucleic acid and cell division in mammalian tissues.", "content": "Correlation between a specific isoaccepting lysyl transfer ribonucleic acid and cell division in mammalian tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355545"}
{"pmid": "4355547", "title": "Nature and possible functions of association between glutamate dehydrogenase and cardiolipin.", "content": "Nature and possible functions of association between glutamate dehydrogenase and cardiolipin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355547"}
{"pmid": "4355549", "title": "Amino acid sequence of a cytochrome c from the common Pacific lamprey, Entosphenus tridentatus.", "content": "Amino acid sequence of a cytochrome c from the common Pacific lamprey, Entosphenus tridentatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355549"}
{"pmid": "4355548", "title": "Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular distribution, and nature of enzyme complexes of the six biosynthetic enzymes.", "content": "Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular distribution, and nature of enzyme complexes of the six biosynthetic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355548"}
{"pmid": "4355550", "title": "Some properties of cross-linked polymers of glutamic dehydrogenase.", "content": "Some properties of cross-linked polymers of glutamic dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355550"}
{"pmid": "4355551", "title": "Synthesis and characterization of photoaffinity labels for adenosine 3':5'-cyclic monophosphate and adenosine 5'-monophosphate.", "content": "Synthesis and characterization of photoaffinity labels for adenosine 3':5'-cyclic monophosphate and adenosine 5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355551"}
{"pmid": "4355552", "title": "On the photoaffinity labeling of rabbit muscle phosphofructokinase with O2'-(ethyl-2-diazomalonyl)adenosine 3':5'-cyclic monophosphate.", "content": "On the photoaffinity labeling of rabbit muscle phosphofructokinase with O2'-(ethyl-2-diazomalonyl)adenosine 3':5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355552"}
{"pmid": "4355553", "title": "Fluorescence properties of octopine dehydrogenase.", "content": "Fluorescence properties of octopine dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355553"}
{"pmid": "4355554", "title": "Independent protein synthesis in isolated rat tumor nucleoli. Aminoacylation of endogenous transfer ribonucleic acid.", "content": "Independent protein synthesis in isolated rat tumor nucleoli. Aminoacylation of endogenous transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355554"}
{"pmid": "4355555", "title": "Characterization of modified myosin at low ionic strength. Enzymatic and spin-label studies.", "content": "Characterization of modified myosin at low ionic strength. Enzymatic and spin-label studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355555"}
{"pmid": "4355556", "title": "Nuclear magnetic resonance and spin-label studies of hemoglobin Kempsey.", "content": "Nuclear magnetic resonance and spin-label studies of hemoglobin Kempsey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355556"}
{"pmid": "4355557", "title": "Immune response to the collagen-like synthetic ordered polypeptide (L-Pro-Gly-L-Pro)n.", "content": "Immune response to the collagen-like synthetic ordered polypeptide (L-Pro-Gly-L-Pro)n.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355557"}
{"pmid": "4355558", "title": "Heterogeneity of the outer membrane of mitochondria.", "content": "Heterogeneity of the outer membrane of mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355558"}
{"pmid": "4355560", "title": "Microcalorimetric study of isolated blood platelets in the presence of thrombin and other aggregating agents.", "content": "Microcalorimetric study of isolated blood platelets in the presence of thrombin and other aggregating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355560"}
{"pmid": "4355559", "title": "Preparation and active-site specific properties of sturgeon muscle glyceraldehyde-3-phoshate dehydrogenase.", "content": "Preparation and active-site specific properties of sturgeon muscle glyceraldehyde-3-phoshate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355559"}
{"pmid": "4355561", "title": "Human chorionic gonadotropin-mediated glycogenolysis in human placental villi: a role of prostaglandins.", "content": "Human chorionic gonadotropin-mediated glycogenolysis in human placental villi: a role of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355561"}
{"pmid": "4355562", "title": "Factors affecting the adrenocorticotropic hormone stimulation of rabbit adrenal 17alpha-hydroxylase activity.", "content": "Factors affecting the adrenocorticotropic hormone stimulation of rabbit adrenal 17alpha-hydroxylase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355562"}
{"pmid": "4355563", "title": "Prolonged retention of high specific activity by 125I-labeled angiotensin II--a consequence of 'decay catastrophe'.", "content": "Prolonged retention of high specific activity by 125I-labeled angiotensin II--a consequence of 'decay catastrophe'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355563"}
{"pmid": "4355564", "title": "Photolumazines, new naturally occurring inhibitors of riboflavin synthetase.", "content": "Photolumazines, new naturally occurring inhibitors of riboflavin synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355564"}
{"pmid": "4355565", "title": "Ionic control of renal gluconeogenesis. II. The effects of Ca2+ and H+ upon the response to parathyroid hormone and cyclic AMP.", "content": "Ionic control of renal gluconeogenesis. II. The effects of Ca2+ and H+ upon the response to parathyroid hormone and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355565"}
{"pmid": "4355566", "title": "Ionic control of renal gluconeogenesis. IV. Effect of extracellular phosphate concentration.", "content": "Ionic control of renal gluconeogenesis. IV. Effect of extracellular phosphate concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355566"}
{"pmid": "4355567", "title": "Endogenous ACTH induced remission in myasthenia gravis.", "content": "Endogenous ACTH induced remission in myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355567"}
{"pmid": "4355568", "title": "Evidence for neuropathy in myotonic muscular dystrophy.", "content": "Evidence for neuropathy in myotonic muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355568"}
{"pmid": "4355570", "title": "The effect of diazoxide in children with islet cell adenomas.", "content": "The effect of diazoxide in children with islet cell adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355570"}
{"pmid": "4355572", "title": "The effect of stress induced by ether anaesthesia on cholesterol content and cholesteryl-esterase activity in rat-adrenal cortex.", "content": "The effect of stress induced by ether anaesthesia on cholesterol content and cholesteryl-esterase activity in rat-adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355572"}
{"pmid": "4355573", "title": "Baldness: a disease?", "content": "Baldness: a disease?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355573"}
{"pmid": "4355574", "title": "Epidemiological factors in lung cancer among women in El Pasco County, Texas 1944-1969.", "content": "Epidemiological factors in lung cancer among women in El Pasco County, Texas 1944-1969.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355574"}
{"pmid": "4355575", "title": "Women's programs at DHEW.", "content": "Women's programs at DHEW.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355575"}
{"pmid": "4355576", "title": "Women doctors educating others. 50th anniversary of the American Medical Women's Association Scholarship Loan Fund.", "content": "Women doctors educating others. 50th anniversary of the American Medical Women's Association Scholarship Loan Fund.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355576"}
{"pmid": "4355577", "title": "Action of Vibrio cholerae neuraminidase (sialidase) upon the surface of intact cells and their isolated sialolipid components.", "content": "Action of Vibrio cholerae neuraminidase (sialidase) upon the surface of intact cells and their isolated sialolipid components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355577"}
{"pmid": "4355579", "title": "Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro.", "content": "Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355579"}
{"pmid": "4355578", "title": "Methionyl residue critical for activity and regulation of bovine liver glutamate dehydrogenase.", "content": "Methionyl residue critical for activity and regulation of bovine liver glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355578"}
{"pmid": "4355580", "title": "Effect of exercise on the turnover of cytochrome c in skeletal muscle.", "content": "Effect of exercise on the turnover of cytochrome c in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355580"}
{"pmid": "4355581", "title": "Effects of insulin on the levels of adenosine 3':5'-monophosphate and lipolysis in isolated rat epididymal fat cells.", "content": "Effects of insulin on the levels of adenosine 3':5'-monophosphate and lipolysis in isolated rat epididymal fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355581"}
{"pmid": "4355582", "title": "Iron and free radical in ribonucleotide reductase. Exchange of iron and Mössbauer spectroscopy of the protein B2 subunit of the Escherichia coli enzyme.", "content": "Iron and free radical in ribonucleotide reductase. Exchange of iron and Mössbauer spectroscopy of the protein B2 subunit of the Escherichia coli enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355582"}
{"pmid": "4355584", "title": "Deoxyribonucleic acid ligase. Isolation and physical characterization of the homogeneous enzyme from Escherichia coli.", "content": "Deoxyribonucleic acid ligase. Isolation and physical characterization of the homogeneous enzyme from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355584"}
{"pmid": "4355583", "title": "Liver cytosol corticosteroid binder II, a hormone receptor.", "content": "Liver cytosol corticosteroid binder II, a hormone receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355583"}
{"pmid": "4355585", "title": "Deoxyribonucleic acid ligase. A steady state kinetic analysis of the reaction catalyzed by the enzyme from Escherichia coli.", "content": "Deoxyribonucleic acid ligase. A steady state kinetic analysis of the reaction catalyzed by the enzyme from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355585"}
{"pmid": "4355586", "title": "Metalloflavoenzyme models. The crystal structure of bis (10-methylisoalloxazine) copper (II) perchlorate tetrahydrate.", "content": "Metalloflavoenzyme models. The crystal structure of bis (10-methylisoalloxazine) copper (II) perchlorate tetrahydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355586"}
{"pmid": "4355587", "title": "Alkylation of an essential histidine residue in porcine spleen deoxyribonuclease.", "content": "Alkylation of an essential histidine residue in porcine spleen deoxyribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355587"}
{"pmid": "4355589", "title": "Physical properties of a purified cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine heart muscle.", "content": "Physical properties of a purified cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355589"}
{"pmid": "4355588", "title": "Receptor for thyrotropin-releasing hormone in plasma membranes of bovine anterior pituitary gland. Role of lipids.", "content": "Receptor for thyrotropin-releasing hormone in plasma membranes of bovine anterior pituitary gland. Role of lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355588"}
{"pmid": "4355590", "title": "Preliminary report on the electron paramagnetic resonance spectra of single crystals of bovine erythrocyte superoxide dismutase.", "content": "Preliminary report on the electron paramagnetic resonance spectra of single crystals of bovine erythrocyte superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355590"}
{"pmid": "4355591", "title": "Determination of aza-heterocyclic compounds in atmospheric dust by a combination of thin-layer and gas chromatography.", "content": "Determination of aza-heterocyclic compounds in atmospheric dust by a combination of thin-layer and gas chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355591"}
{"pmid": "4355592", "title": "Role of adrenal hormones in incubation behavior of male ring doves (Streptopelia risoria).", "content": "Role of adrenal hormones in incubation behavior of male ring doves (Streptopelia risoria).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355592"}
{"pmid": "4355593", "title": "Synthesis and antiviral activity of 1,2,4-triazole-3-thiocarboxamide and 1,2,4-triazole-3-carboxamidine ribonucleosides.", "content": "Synthesis and antiviral activity of 1,2,4-triazole-3-thiocarboxamide and 1,2,4-triazole-3-carboxamidine ribonucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355593"}
{"pmid": "4355594", "title": "Synthesis of 5'-phosphates of the naturally occurring 6-ureidopurine ribonucleosides and their analogs.", "content": "Synthesis of 5'-phosphates of the naturally occurring 6-ureidopurine ribonucleosides and their analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355594"}
{"pmid": "4355595", "title": "Different cyclic AMP requirements for induction of the arabinose and lactose operons of Escherichia coli.", "content": "Different cyclic AMP requirements for induction of the arabinose and lactose operons of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355595"}
{"pmid": "4355596", "title": "RNA-directed DNA polymerase of Rous sarcoma virus: initiation of synthesis with 70 S viral RNA as template.", "content": "RNA-directed DNA polymerase of Rous sarcoma virus: initiation of synthesis with 70 S viral RNA as template.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355596"}
{"pmid": "4355597", "title": "Recurrence of the cytochrome fold in a nitrate-respiring bacterium.", "content": "Recurrence of the cytochrome fold in a nitrate-respiring bacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355597"}
{"pmid": "4355598", "title": "Mutagenic specificity: reversion of iso-1-cytochrome c mutants of yeast.", "content": "Mutagenic specificity: reversion of iso-1-cytochrome c mutants of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355598"}
{"pmid": "4355599", "title": "Public health implications of Marek's disease virus and herpesvirus of turkeyes. Studies on human and subhuman primates.", "content": "Public health implications of Marek's disease virus and herpesvirus of turkeyes. Studies on human and subhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355599"}
{"pmid": "4355600", "title": "Preparation of membrane fractions with enhanced tumor-transplantation-antigen activity from tumor cells infected with influenza virus.", "content": "Preparation of membrane fractions with enhanced tumor-transplantation-antigen activity from tumor cells infected with influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355600"}
{"pmid": "4355601", "title": "Lymphomas in BALB-c mice inoculated with supernatants from chemically induced sarcomas.", "content": "Lymphomas in BALB-c mice inoculated with supernatants from chemically induced sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355601"}
{"pmid": "4355602", "title": "Differential response of rat tooth germs to a murine sarcoma virus in cell culture and syngeneic transplants.", "content": "Differential response of rat tooth germs to a murine sarcoma virus in cell culture and syngeneic transplants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355602"}
{"pmid": "4355603", "title": "Prevalence of type-C particles in visceral tissues of embryonic and newborn mice.", "content": "Prevalence of type-C particles in visceral tissues of embryonic and newborn mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355603"}
{"pmid": "4355604", "title": "XC cell cytopathogenicity as an assay for murine myeloma C-type virus.", "content": "XC cell cytopathogenicity as an assay for murine myeloma C-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355604"}
{"pmid": "4355605", "title": "A spontaneous lower motor neuron disease apparently caused by indigenous type-C RNA virus in wild mice.", "content": "A spontaneous lower motor neuron disease apparently caused by indigenous type-C RNA virus in wild mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355605"}
{"pmid": "4355606", "title": "Rous sarcoma virus-induced tumors in marmosets: characteristics of tumor cells and host cell-virus interrelationships.", "content": "Rous sarcoma virus-induced tumors in marmosets: characteristics of tumor cells and host cell-virus interrelationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355606"}
{"pmid": "4355607", "title": "Effect of streptozotocin in the Chinese hamster (Cricetulus griseus).", "content": "Effect of streptozotocin in the Chinese hamster (Cricetulus griseus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355607"}
{"pmid": "4355609", "title": "Brief communication: In vitro host range and serologic studies on RD-114 virus.", "content": "Brief communication: In vitro host range and serologic studies on RD-114 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355609"}
{"pmid": "4355608", "title": "Brief communication: circulating antigen-antibody complex associated with Epstein-Barr virus in recurrent Burkitt's lymphoma.", "content": "Brief communication: circulating antigen-antibody complex associated with Epstein-Barr virus in recurrent Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355608"}
{"pmid": "4355610", "title": "Stereochemistry in the solvolytic ring contraction of 2,2,4a alpha-trimethyl-1-decalyl methanesulfonate. A model reaction pertaining to triterpene biogenesis.", "content": "Stereochemistry in the solvolytic ring contraction of 2,2,4a alpha-trimethyl-1-decalyl methanesulfonate. A model reaction pertaining to triterpene biogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355610"}
{"pmid": "4355620", "title": "Skin test in bronchogenic carcinoma. I. Correlation of the immunological status and the extent of the disease.", "content": "Skin test in bronchogenic carcinoma. I. Correlation of the immunological status and the extent of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355620"}
{"pmid": "4355622", "title": "Pseudomonas meningitis complicating radical resection for radiorecurrent cancer of the paranasal sinuses: report of two patients successfully treated with intrathecal polymyxin.", "content": "Pseudomonas meningitis complicating radical resection for radiorecurrent cancer of the paranasal sinuses: report of two patients successfully treated with intrathecal polymyxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355622"}
{"pmid": "4355621", "title": "Cross-classification and survival characteristics of 5,000 cases of cancer of the pancreas.", "content": "Cross-classification and survival characteristics of 5,000 cases of cancer of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355621"}
{"pmid": "4355623", "title": "Water pollution: microbiology of water.", "content": "Water pollution: microbiology of water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355623"}
{"pmid": "4355612", "title": "Managing member silence in family therapy.", "content": "Managing member silence in family therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355612"}
{"pmid": "4355611", "title": "Implications of the incest taboo for nursing practice.", "content": "Implications of the incest taboo for nursing practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355611"}
{"pmid": "4355625", "title": "Radiotherapy of adenoid cystic carcinoma of the head and neck.", "content": "Radiotherapy of adenoid cystic carcinoma of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355625"}
{"pmid": "4355624", "title": "Microbiology--detection and occurrence of viruses.", "content": "Microbiology--detection and occurrence of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355624"}
{"pmid": "4355613", "title": "The CVA patient as an indication of general patient need.", "content": "The CVA patient as an indication of general patient need.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355613"}
{"pmid": "4355614", "title": "Philosophy and structure of a day treatment center.", "content": "Philosophy and structure of a day treatment center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355614"}
{"pmid": "4355615", "title": "The role of science in the World Health Organization.", "content": "The role of science in the World Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355615"}
{"pmid": "4355616", "title": "Speaking out on: professional rejection of the longer-term patient??", "content": "Speaking out on: professional rejection of the longer-term patient??", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355616"}
{"pmid": "4355618", "title": "Problems of a nurse group on an inpatient psychiatric unit.", "content": "Problems of a nurse group on an inpatient psychiatric unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355618"}
{"pmid": "4355629", "title": "Management of alleged sexual assault.", "content": "Management of alleged sexual assault.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355629"}
{"pmid": "4355630", "title": "A comparative follow-up of functional psychoses in women.", "content": "A comparative follow-up of functional psychoses in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355630"}
{"pmid": "4355617", "title": "Food for the elderly.", "content": "Food for the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355617"}
{"pmid": "4355631", "title": "Rapid new soft x-ray technique for determination of quartz in coal mine dusts.", "content": "Rapid new soft x-ray technique for determination of quartz in coal mine dusts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355631"}
{"pmid": "4355632", "title": "Epidemiology of respiratory syncytial virus infection in Washington, D.C. 3. Composite analysis of eleven consecutive yearly epidemics.", "content": "Epidemiology of respiratory syncytial virus infection in Washington, D.C. 3. Composite analysis of eleven consecutive yearly epidemics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355632"}
{"pmid": "4355619", "title": "Organization of emergency services: the crisis nurse in the community mental health center.", "content": "Organization of emergency services: the crisis nurse in the community mental health center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355619"}
{"pmid": "4355633", "title": "Adrenocortical function in acromegaly.", "content": "Adrenocortical function in acromegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355633"}
{"pmid": "4355634", "title": "The road to Shangri-La is paved with vitamins.", "content": "The road to Shangri-La is paved with vitamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355634"}
{"pmid": "4355635", "title": "Antagonism of d-tubocurarine- and pancuronium-induced neuromuscular blockades by pyridostigmine in man.", "content": "Antagonism of d-tubocurarine- and pancuronium-induced neuromuscular blockades by pyridostigmine in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355635"}
{"pmid": "4355636", "title": "Halothane stereoisomers: lack of stereospecificity in two model systems.", "content": "Halothane stereoisomers: lack of stereospecificity in two model systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355636"}
{"pmid": "4355637", "title": "Letter: Standardized technique for transmission studies.", "content": "Letter: Standardized technique for transmission studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355637"}
{"pmid": "4355638", "title": "Postoperative endophthalmitis following cataract surgery. Effects on subconjunctival antibiotics and other factrs.", "content": "Postoperative endophthalmitis following cataract surgery. Effects on subconjunctival antibiotics and other factrs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355638"}
{"pmid": "4355640", "title": "Endocrine spotlights on brain and behaviour.", "content": "Endocrine spotlights on brain and behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355640"}
{"pmid": "4355639", "title": "Chronic ulcerative keratitis caused by herpes simplex virus.", "content": "Chronic ulcerative keratitis caused by herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355639"}
{"pmid": "4355643", "title": "An insoluble fibrogenic factor in macrophages from guinea pigs exposed to silica.", "content": "An insoluble fibrogenic factor in macrophages from guinea pigs exposed to silica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355643"}
{"pmid": "4355644", "title": "Noradrenergic pathways and sleep-waking states in cats.", "content": "Noradrenergic pathways and sleep-waking states in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355644"}
{"pmid": "4355645", "title": "Polarization changes in the terminals of identified primary afferent fibers at the gracile nucleus.", "content": "Polarization changes in the terminals of identified primary afferent fibers at the gracile nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355645"}
{"pmid": "4355646", "title": "Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires.", "content": "Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355646"}
{"pmid": "4355654", "title": "Molybdenum(IV) in aqueous solutions.", "content": "Molybdenum(IV) in aqueous solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355654"}
{"pmid": "4355655", "title": "Dysfunction patterns analogous to frontal lobe system and caudate nucleus syndromes in some groups of minimal brain dysfunction.", "content": "Dysfunction patterns analogous to frontal lobe system and caudate nucleus syndromes in some groups of minimal brain dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355655"}
{"pmid": "4355656", "title": "Is anatomy destiny? Panel: the changing role of women psychiatrists.", "content": "Is anatomy destiny? Panel: the changing role of women psychiatrists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355656"}
{"pmid": "4355657", "title": "New Jersey women physicians--their opinions on today's world.", "content": "New Jersey women physicians--their opinions on today's world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355657"}
{"pmid": "4355658", "title": "Hypertension in terminal renal failure. Observations pre and post bilateral nephrectomy.", "content": "Hypertension in terminal renal failure. Observations pre and post bilateral nephrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355658"}
{"pmid": "4355659", "title": "Renovascular hypertension: incidence, diagnosis, mechanism and treatment.", "content": "Renovascular hypertension: incidence, diagnosis, mechanism and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355659"}
{"pmid": "4355661", "title": "Antagonism of vasoconstrictor responses by exercise in the gracilis muscle of the dog.", "content": "Antagonism of vasoconstrictor responses by exercise in the gracilis muscle of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355661"}
{"pmid": "4355662", "title": "A new technique for treating esophageal varices.", "content": "A new technique for treating esophageal varices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355662"}
{"pmid": "4355665", "title": "Nephroblastoma: index cancer of childhood.", "content": "Nephroblastoma: index cancer of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355665"}
{"pmid": "4355666", "title": "Low back pain. Differential diagnosis determines treatment: hospitalization enables more efficient treatment.", "content": "Low back pain. Differential diagnosis determines treatment: hospitalization enables more efficient treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355666"}
{"pmid": "4355667", "title": "Morphine tolerance and supersensitivity to 5-hydroxytryptamine in the myenteric plexus of the guinea-pig.", "content": "Morphine tolerance and supersensitivity to 5-hydroxytryptamine in the myenteric plexus of the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355667"}
{"pmid": "4355668", "title": "Vitamin D-like action of Solanum malacoxylon on calcium transport by rat intestine.", "content": "Vitamin D-like action of Solanum malacoxylon on calcium transport by rat intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355668"}
{"pmid": "4355660", "title": "Stannous pyrophosphate labeled with technetium-99m for skeletal scintigraphy.", "content": "Stannous pyrophosphate labeled with technetium-99m for skeletal scintigraphy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355660"}
{"pmid": "4355669", "title": "Effect of cyclic AMP on growth and morphological differentiation of an established myogenic cell line.", "content": "Effect of cyclic AMP on growth and morphological differentiation of an established myogenic cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355669"}
{"pmid": "4355670", "title": "Agglutination with con A dependent on cell cycle.", "content": "Agglutination with con A dependent on cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355670"}
{"pmid": "4355671", "title": "Depletion of serum growth factors by 3T3 mouse fibroblasts and viral transformants.", "content": "Depletion of serum growth factors by 3T3 mouse fibroblasts and viral transformants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355671"}
{"pmid": "4355672", "title": "Adrenaline-like effects of intracellular iontophoresis of cyclic AMP in cardiac Purkinje fibres.", "content": "Adrenaline-like effects of intracellular iontophoresis of cyclic AMP in cardiac Purkinje fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355672"}
{"pmid": "4355673", "title": "NMR evidence against gamma turn and beta turn models of angiotensin II in aqueous solution.", "content": "NMR evidence against gamma turn and beta turn models of angiotensin II in aqueous solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355673"}
{"pmid": "4355674", "title": "Electronic sector scanning in the diagnosis of cerebrovascular disease and space-occupying processes.", "content": "Electronic sector scanning in the diagnosis of cerebrovascular disease and space-occupying processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355674"}
{"pmid": "4355675", "title": "Serum immunoglobulin and complement (C3) levels: a study in adults with idiopathic, chronic polyneuropathies and motor neuron diseases.", "content": "Serum immunoglobulin and complement (C3) levels: a study in adults with idiopathic, chronic polyneuropathies and motor neuron diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355675"}
{"pmid": "4355676", "title": "The effect of cold on nerve conduction of human slow and fast nerve fibers.", "content": "The effect of cold on nerve conduction of human slow and fast nerve fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355676"}
{"pmid": "4355677", "title": "Studies on the synaptic facilitatory action of nikethamide.", "content": "Studies on the synaptic facilitatory action of nikethamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355677"}
{"pmid": "4355678", "title": "Electroencephalographic study of the effects of tetrahydrocannabinols on sleep in the rat.", "content": "Electroencephalographic study of the effects of tetrahydrocannabinols on sleep in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355678"}
{"pmid": "4355679", "title": "Functional organelles in prokaryotes: polyhedral inclusions (carboxysomes) of Thiobacillus neapolitanus.", "content": "Functional organelles in prokaryotes: polyhedral inclusions (carboxysomes) of Thiobacillus neapolitanus. The polyhedral inclusions of Thiobacillus neapolitanus have been isolated; they contain ribulose diphosphate carboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355679"}
{"pmid": "4355680", "title": "Rapid viral induction of plasmacytomas in pristane-primed BALB-c mice.", "content": "Rapid viral induction of plasmacytomas in pristane-primed BALB-c mice. Strain BALB/c mice were injected intraperitoneally with 0.5 milliliter of pristane, and 39 to 56 days later they were infected with Abelson murine leukemia virus, which is a lymphosarcomagenic variant of Moloney virus. Fifty-eight percent of the mice developed lymphosarcoma, and 28 percent developed immunoglobulin-producing plasmacytomas within 20 to 93 days (77 to 149 days after the pristane injection). Two of 57 control mice developed plasmacytomas at days 138 and 166 after a single injection of pristane; no plasmacytomas were found in mice treated with virus alone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355680"}
{"pmid": "4355681", "title": "Collagen synthesis: localization of prolyl hydroxylase in tendon cells detected with ferritin-labeled antibodies.", "content": "Collagen synthesis: localization of prolyl hydroxylase in tendon cells detected with ferritin-labeled antibodies. An improved procedure was employed for linking ferritin to antibodies against prolyl hydroxylase, the enzyme that synthesizes the hydroxyproline in collagen. By electron microscopy, the enzyme was then found to be localized in cisternae of the rough endoplasmic reticulum of embryonic tendon cells; this indicates that hydroxylation of proline occurs while newly synthesized polypeptides are fed into the cisternae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355681"}
{"pmid": "4355688", "title": "Gastric acid secretion in insulin-secreting tumors of the pancreas.", "content": "Gastric acid secretion in insulin-secreting tumors of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355688"}
{"pmid": "4355689", "title": "Isolation of viable cells from experimental granulation tissue.", "content": "Isolation of viable cells from experimental granulation tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355689"}
{"pmid": "4355690", "title": "IgM-producing malignant lymphomas without macroglobulinemia. Morphological and immunochemical findings.", "content": "IgM-producing malignant lymphomas without macroglobulinemia. Morphological and immunochemical findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355690"}
{"pmid": "4355692", "title": "A histochemical study of the inclusion bodies in the small intestine of the developing rat.", "content": "A histochemical study of the inclusion bodies in the small intestine of the developing rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355692"}
{"pmid": "4355693", "title": "The structure of the gill of the trout, Salmo gairdneri (Richardson).", "content": "The structure of the gill of the trout, Salmo gairdneri (Richardson).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355693"}
{"pmid": "4355696", "title": "Herpesvirus encephalitis following herpes keratitis.", "content": "Herpesvirus encephalitis following herpes keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355696"}
{"pmid": "4355694", "title": "Effects of colchicine and vinblastine on neurotubules of the sciatic nerve and cholinesterases in the developing myoneural junction of the rat.", "content": "Effects of colchicine and vinblastine on neurotubules of the sciatic nerve and cholinesterases in the developing myoneural junction of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355694"}
{"pmid": "4355695", "title": "Evidence for basal secretion in the subcommissural organ of the adult rabbit.", "content": "Evidence for basal secretion in the subcommissural organ of the adult rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355695"}
{"pmid": "4355698", "title": "Intracranial arterial occlusion in children. Diagnosis and follow-up by brain scanning.", "content": "Intracranial arterial occlusion in children. Diagnosis and follow-up by brain scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355698"}
{"pmid": "4355697", "title": "Congenital anomalies and herpesvirus infection.", "content": "Congenital anomalies and herpesvirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355697"}
{"pmid": "4355699", "title": "Vasoconstriction-volume analysis for understanding and treating hypertension: the use of renin and aldosterone profiles.", "content": "Vasoconstriction-volume analysis for understanding and treating hypertension: the use of renin and aldosterone profiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355699"}
{"pmid": "4355700", "title": "Searching out low renin patients: limitations of some commonly used methods.", "content": "Searching out low renin patients: limitations of some commonly used methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355700"}
{"pmid": "4355701", "title": "Renin, angiotensin and hypertensive vascular damage: a review.", "content": "Renin, angiotensin and hypertensive vascular damage: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355701"}
{"pmid": "4355702", "title": "The control of renin release.", "content": "The control of renin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355702"}
{"pmid": "4355703", "title": "Neurogenic factors in human hypertension: mechanism or myth?", "content": "Neurogenic factors in human hypertension: mechanism or myth?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355703"}
{"pmid": "4355704", "title": "Hypertension in chronic renal failure. An abnormal relation between sodium and the renin-angiotensin system.", "content": "Hypertension in chronic renal failure. An abnormal relation between sodium and the renin-angiotensin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355704"}
{"pmid": "4355705", "title": "Cushing's syndrome caused by recurrent malignant bronchial carcinod. Case report with 12 years' observation.", "content": "Cushing's syndrome caused by recurrent malignant bronchial carcinod. Case report with 12 years' observation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355705"}
{"pmid": "4355706", "title": "An experimental study of the effects of drains on colon anastomoses.", "content": "An experimental study of the effects of drains on colon anastomoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355706"}
{"pmid": "4355707", "title": "Pressure synthesis of thioformamide.", "content": "Pressure synthesis of thioformamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355707"}
{"pmid": "4355708", "title": "Homogeneous catalysis by transition metal complexes. 3. A new cobalt-cyanide catalyst for selective homogeneous hydrogenation of dienes.", "content": "Homogeneous catalysis by transition metal complexes. 3. A new cobalt-cyanide catalyst for selective homogeneous hydrogenation of dienes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355708"}
{"pmid": "4355711", "title": "Mechanism of the antihypertensive effect of 1-Sar-8-Ala-angiotensin II during the acute phase of experimental renal hypertension.", "content": "Mechanism of the antihypertensive effect of 1-Sar-8-Ala-angiotensin II during the acute phase of experimental renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355711"}
{"pmid": "4355710", "title": "Dopamine-induced neurogenic vasodilatation: antagonism at the vascular level.", "content": "Dopamine-induced neurogenic vasodilatation: antagonism at the vascular level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355710"}
{"pmid": "4355713", "title": "Ocular response to corticotropin in myasthenia gravis.", "content": "Ocular response to corticotropin in myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355713"}
{"pmid": "4355712", "title": "Influence of vasoactive hormones on blood flow through the mammary artery in lactating cows.", "content": "Influence of vasoactive hormones on blood flow through the mammary artery in lactating cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355712"}
{"pmid": "4355714", "title": "Malignant mixed tumor of the lacrimal gland. Occult source of metastatic carcinoma.", "content": "Malignant mixed tumor of the lacrimal gland. Occult source of metastatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355714"}
{"pmid": "4355715", "title": "The role of vitamin D metabolites in bone resorption.", "content": "The role of vitamin D metabolites in bone resorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355715"}
{"pmid": "4355716", "title": "Repolarization-induced reactivation of contracture tension in frog skeletal muscle.", "content": "Repolarization-induced reactivation of contracture tension in frog skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355716"}
{"pmid": "4355718", "title": "Influence of acute stimuli on plasma aldosterone concentration in anephric man and kidney allograft recipients.", "content": "Influence of acute stimuli on plasma aldosterone concentration in anephric man and kidney allograft recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355718"}
{"pmid": "4355717", "title": "Pharmacologic receptor activity of rabbit aorta. Effect of dithiothreitol and N-ethylmaleimide.", "content": "Pharmacologic receptor activity of rabbit aorta. Effect of dithiothreitol and N-ethylmaleimide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355717"}
{"pmid": "4355720", "title": "A rapid competitive protein-binding assay of unconjugated oestradiol in late pregnancy plasma.", "content": "A rapid competitive protein-binding assay of unconjugated oestradiol in late pregnancy plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355720"}
{"pmid": "4355721", "title": "Determination of urinary amino acids by gas chromatography.", "content": "Determination of urinary amino acids by gas chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355721"}
{"pmid": "4355723", "title": "Biochemical properties of normal and neoplastic cell surfaces; a review.", "content": "Biochemical properties of normal and neoplastic cell surfaces; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355723"}
{"pmid": "4355722", "title": "Polyacrylamide gel electrophoresis as a method for differentiation and quantitation of serum enzymes hydrolysing phosphate monoesters.", "content": "Polyacrylamide gel electrophoresis as a method for differentiation and quantitation of serum enzymes hydrolysing phosphate monoesters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355722"}
{"pmid": "4355725", "title": "The cytotoxicity of chlorambucil and its associated effects on NAD metabolism.", "content": "The cytotoxicity of chlorambucil and its associated effects on NAD metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355725"}
{"pmid": "4355724", "title": "Wilm's tumour treated at the Rotterdam Radiotherapy Institute (1964-1971).", "content": "Wilm's tumour treated at the Rotterdam Radiotherapy Institute (1964-1971).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355724"}
{"pmid": "4355727", "title": "Standards for the assessment of estrogen receptors in human breast cancer. Report of a workshop on September 29, 1972, at the Antoni van Leeuwenhoek-Huis, Amsterdam.", "content": "Standards for the assessment of estrogen receptors in human breast cancer. Report of a workshop on September 29, 1972, at the Antoni van Leeuwenhoek-Huis, Amsterdam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355727"}
{"pmid": "4355726", "title": "Content of estrogen receptors in human breast cancer.", "content": "Content of estrogen receptors in human breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355726"}
{"pmid": "4355729", "title": "Induction of stimulus-bound repetition in sympathetic ganglia by germine-mono-acetate.", "content": "Induction of stimulus-bound repetition in sympathetic ganglia by germine-mono-acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355729"}
{"pmid": "4355728", "title": "The effects of PGE1 on responses to cardiac vagus nerve stimulation and acetylcholine release.", "content": "The effects of PGE1 on responses to cardiac vagus nerve stimulation and acetylcholine release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355728"}
{"pmid": "4355730", "title": "Cyclic adenosine 3',5'-monophosphate concentration in rabbit parotid slices following stimulation by secretagotues.", "content": "Cyclic adenosine 3',5'-monophosphate concentration in rabbit parotid slices following stimulation by secretagotues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355730"}
{"pmid": "4355731", "title": "Prostaglandin release from vasculature by angiotensin II: dissociation from lipolysis.", "content": "Prostaglandin release from vasculature by angiotensin II: dissociation from lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355731"}
{"pmid": "4355732", "title": "Synaptic biochemistry of amino acids.", "content": "Synaptic biochemistry of amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355732"}
{"pmid": "4355734", "title": "Studies of human amebiasis. II. Light and electron-microscopic observations of colonic mucosa and exudate in acute amebic colitis.", "content": "Studies of human amebiasis. II. Light and electron-microscopic observations of colonic mucosa and exudate in acute amebic colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355734"}
{"pmid": "4355735", "title": "Rapid serological methods for the demonstration of Entamoeba histolytica activity.", "content": "Rapid serological methods for the demonstration of Entamoeba histolytica activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355735"}
{"pmid": "4355733", "title": "Studies of human amebiasis. I. Clinical and laboratory findings in eight cases of acute amebic colitis.", "content": "Studies of human amebiasis. I. Clinical and laboratory findings in eight cases of acute amebic colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355733"}
{"pmid": "4355736", "title": "Letter: Effect of beta stimulant on eosinopenic responses.", "content": "Letter: Effect of beta stimulant on eosinopenic responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355736"}
{"pmid": "4355738", "title": "Neurite development in vitro. II. The role of microfilaments and microtubules in dibutyryl adenosine 3',5'-cyclic monophosphate and nerve growth factor stimulated maturation.", "content": "Neurite development in vitro. II. The role of microfilaments and microtubules in dibutyryl adenosine 3',5'-cyclic monophosphate and nerve growth factor stimulated maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355738"}
{"pmid": "4355737", "title": "Chlorpromazine: effects of antacids on its gastrointestinal absorption.", "content": "Chlorpromazine: effects of antacids on its gastrointestinal absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355737"}
{"pmid": "4355739", "title": "Experimental inhibition of myelination in spinal cord tissue cultures: enzyme assays.", "content": "Experimental inhibition of myelination in spinal cord tissue cultures: enzyme assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355739"}
{"pmid": "4355740", "title": "Fasting hypoglycemia.", "content": "Fasting hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355740"}
{"pmid": "4355741", "title": "Acute renal failure.", "content": "Acute renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355741"}
{"pmid": "4355743", "title": "The response to chemical mutagens of the individual haploid and homoallelic diploid UV-sensitive mutants of the rad 3 locus of Saccharomyces cerevisiae.", "content": "The response to chemical mutagens of the individual haploid and homoallelic diploid UV-sensitive mutants of the rad 3 locus of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355743"}
{"pmid": "4355745", "title": "Cytoplasmic proteins regulating messenger RNA release from nuclei.", "content": "Cytoplasmic proteins regulating messenger RNA release from nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355745"}
{"pmid": "4355744", "title": "RNA-directed cell-free synthesis of the galactose enzymes of Escherichia coli.", "content": "RNA-directed cell-free synthesis of the galactose enzymes of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355744"}
{"pmid": "4355746", "title": "Discontinuous elongation of both strands at the replication forks in polyoma DNA replication.", "content": "Discontinuous elongation of both strands at the replication forks in polyoma DNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355746"}
{"pmid": "4355747", "title": "Immunospecificity to non-histone chromosomal proteins of anti-chromatin antibodies.", "content": "Immunospecificity to non-histone chromosomal proteins of anti-chromatin antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355747"}
{"pmid": "4355749", "title": "The accumulation of 32P-polyphosphates of calcium, magnesium, lanthanum and sodium by tumor bearing animals: its radiotherapeutical significance.", "content": "The accumulation of 32P-polyphosphates of calcium, magnesium, lanthanum and sodium by tumor bearing animals: its radiotherapeutical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355749"}
{"pmid": "4355750", "title": "Photochemical labeling of yeast alcohol dehydrogenase with an azide analog of NAD+.", "content": "Photochemical labeling of yeast alcohol dehydrogenase with an azide analog of NAD+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355750"}
{"pmid": "4355752", "title": "Effect of polymyxin B and endotoxin on renal cortical fibrinolysis.", "content": "Effect of polymyxin B and endotoxin on renal cortical fibrinolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355752"}
{"pmid": "4355753", "title": "Evidence for glycosylated crosslinks in body-wall collagen of the sea cucumber, Thyome briareus.", "content": "Evidence for glycosylated crosslinks in body-wall collagen of the sea cucumber, Thyome briareus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355753"}
{"pmid": "4355755", "title": "Acid liability of rhinovirus type 14: effect of pH, time, and temperature.", "content": "Acid liability of rhinovirus type 14: effect of pH, time, and temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355755"}
{"pmid": "4355754", "title": "The role of adenine nucleotides and the effect of caffeine and dibutyryl cyclic AMP on the metabolism of guinea pig epididymal spermatozoa.", "content": "The role of adenine nucleotides and the effect of caffeine and dibutyryl cyclic AMP on the metabolism of guinea pig epididymal spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355754"}
{"pmid": "4355751", "title": "Energy transfer between nucleic acid bases and tryptophan in aggregates and in oligopeptide-nucleic acid complexes.", "content": "Energy transfer between nucleic acid bases and tryptophan in aggregates and in oligopeptide-nucleic acid complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355751"}
{"pmid": "4355756", "title": "The effects of metyrapone and ACTH on the development of gluconeogenesis in the neonatal pig.", "content": "The effects of metyrapone and ACTH on the development of gluconeogenesis in the neonatal pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355756"}
{"pmid": "4355757", "title": "Heterologous activity of monkey interferons.", "content": "Heterologous activity of monkey interferons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355757"}
{"pmid": "4355758", "title": "Nicotinamide adenine dinucleotide (NAD) content of liver with hemorrhagic shock.", "content": "Nicotinamide adenine dinucleotide (NAD) content of liver with hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355758"}
{"pmid": "4355759", "title": "Influence of preinfection of C57BL-L mice with Graffi leukemia virus on 3-methylcholanthren-induced subcutaneous sarcoma.", "content": "Influence of preinfection of C57BL-L mice with Graffi leukemia virus on 3-methylcholanthren-induced subcutaneous sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355759"}
{"pmid": "4355760", "title": "Abortive herpes simplex virus replication in Rous sarcoma virus transformed cells.", "content": "Abortive herpes simplex virus replication in Rous sarcoma virus transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355760"}
{"pmid": "4355761", "title": "Pathogenetic studies of herpes simplex virus infection of the rabbit eye.", "content": "Pathogenetic studies of herpes simplex virus infection of the rabbit eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355761"}
{"pmid": "4355762", "title": "Incorporation of a phospholipid precursor into the subcellular organelles of 9-methylpteroylglutamic acid-treated rat embryos.", "content": "Incorporation of a phospholipid precursor into the subcellular organelles of 9-methylpteroylglutamic acid-treated rat embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355762"}
{"pmid": "4355767", "title": "Enzymes of arginine and urea synthesis.", "content": "Enzymes of arginine and urea synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355767"}
{"pmid": "4355768", "title": "The amidotransferases.", "content": "The amidotransferases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355768"}
{"pmid": "4355769", "title": "Parainfluenza-3 and bovine enteroviruses as possible important causative factors in bovine abortion.", "content": "Parainfluenza-3 and bovine enteroviruses as possible important causative factors in bovine abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355769"}
{"pmid": "4355770", "title": "Immunogenicity of canine distemper virus vaccine produced in a continuous cell line (LLC-MK2 cells).", "content": "Immunogenicity of canine distemper virus vaccine produced in a continuous cell line (LLC-MK2 cells).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355770"}
{"pmid": "4355771", "title": "Bile duct carcinoma in cattle: three case reports.", "content": "Bile duct carcinoma in cattle: three case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355771"}
{"pmid": "4355772", "title": "Correlation between TS phenotype and pathogenicity of some animal viruses.", "content": "Correlation between TS phenotype and pathogenicity of some animal viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355772"}
{"pmid": "4355773", "title": "Studies on reovirus type 2: viral interference with UV-inactived virus.", "content": "Studies on reovirus type 2: viral interference with UV-inactived virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355773"}
{"pmid": "4355774", "title": "The effect of different media on maintenance of chick embryo tracheal organ cultures and replication of influenza virus. Brief report.", "content": "The effect of different media on maintenance of chick embryo tracheal organ cultures and replication of influenza virus. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355774"}
{"pmid": "4355778", "title": "The influence of dipyridamol on changes in the heart induced with posterior pituitary extract.", "content": "The influence of dipyridamol on changes in the heart induced with posterior pituitary extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355778"}
{"pmid": "4355779", "title": "Case report of a familial oxalosis (ultrastructural study on the pathogenesis of kidney changes).", "content": "Case report of a familial oxalosis (ultrastructural study on the pathogenesis of kidney changes).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355779"}
{"pmid": "4355781", "title": "Effect of a single injection of betamethasone disodium phosphate on the synthesis of collagen and noncollagen protein of carrageenin granuloma in rats.", "content": "Effect of a single injection of betamethasone disodium phosphate on the synthesis of collagen and noncollagen protein of carrageenin granuloma in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355781"}
{"pmid": "4355780", "title": "Effect of antimycin A on hormone-stimulated lipolysis in vitro.", "content": "Effect of antimycin A on hormone-stimulated lipolysis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355780"}
{"pmid": "4355782", "title": "Localization and characterization of the inhibitory action of ethacrynic acid on glycolysis.", "content": "Localization and characterization of the inhibitory action of ethacrynic acid on glycolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355782"}
{"pmid": "4355783", "title": "Identification of (-)-delta 9-6a,10a-trans-tetrahydrocannabinol and two of its metabolites in rats by use of combination gas chromatography-mass spectrometry and mass fragmentography.", "content": "Identification of (-)-delta 9-6a,10a-trans-tetrahydrocannabinol and two of its metabolites in rats by use of combination gas chromatography-mass spectrometry and mass fragmentography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355783"}
{"pmid": "4355784", "title": "The mode of action of beta-benzal butyric acid, an hypocholesterolemic drug, in affecting mitochondrial respiration.", "content": "The mode of action of beta-benzal butyric acid, an hypocholesterolemic drug, in affecting mitochondrial respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355784"}
{"pmid": "4355785", "title": "Effect of hydrocortisone acetate, fluocinolone acetonide, fluclorolone acetonide, betamethasone-17-valerate and fluprednyliden-21-acetate on collagen biosynthesis.", "content": "Effect of hydrocortisone acetate, fluocinolone acetonide, fluclorolone acetonide, betamethasone-17-valerate and fluprednyliden-21-acetate on collagen biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355785"}
{"pmid": "4355787", "title": "Reaction of cytochrome c with one-electron redox reagents. I. Reduction of ferricytochrome c by the hydrated electron produced by pulse radiolysis.", "content": "Reaction of cytochrome c with one-electron redox reagents. I. Reduction of ferricytochrome c by the hydrated electron produced by pulse radiolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355787"}
{"pmid": "4355786", "title": "Hepatic free radical levels in ethanol-treated and carbon tetrachloride-treated rats.", "content": "Hepatic free radical levels in ethanol-treated and carbon tetrachloride-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355786"}
{"pmid": "4355788", "title": "CO-binding pigments and the functional terminal oxidase of the trypanosomatid hemoflagellate Crithidia fasciculata.", "content": "CO-binding pigments and the functional terminal oxidase of the trypanosomatid hemoflagellate Crithidia fasciculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355788"}
{"pmid": "4355789", "title": "Electron spin resonance characterization of Chromatium D hemes, non-heme irons and the components involved in primary photochemistry.", "content": "Electron spin resonance characterization of Chromatium D hemes, non-heme irons and the components involved in primary photochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355789"}
{"pmid": "4355790", "title": "Nucleoside transport in normal and polyoma-transformed cells: kinetic differences following adenosine and serum or insulin stimulation.", "content": "Nucleoside transport in normal and polyoma-transformed cells: kinetic differences following adenosine and serum or insulin stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355790"}
{"pmid": "4355792", "title": "Purification and properties of a nucleolar endoribonuclease from Novikoff hepatoma.", "content": "Purification and properties of a nucleolar endoribonuclease from Novikoff hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355792"}
{"pmid": "4355791", "title": "A rapid high yield method for the preparation of rat liver cell plasma membranes.", "content": "A rapid high yield method for the preparation of rat liver cell plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355791"}
{"pmid": "4355793", "title": "Oxidative phosphorylation in immature rat brain mitochondria.", "content": "Oxidative phosphorylation in immature rat brain mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355793"}
{"pmid": "4355794", "title": "The lipid composition of plasma lipoprotein density classes of sheep Ovis aries.", "content": "The lipid composition of plasma lipoprotein density classes of sheep Ovis aries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355794"}
{"pmid": "4355795", "title": "Cyclic nucleotide phosphodiesterase from Tetrahymena.", "content": "Cyclic nucleotide phosphodiesterase from Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355795"}
{"pmid": "4355802", "title": "Health planning as a managerial ideology.", "content": "Health planning as a managerial ideology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355802"}
{"pmid": "4355803", "title": "Aspects of adrenal function in neonatally estrogenized male mice.", "content": "Aspects of adrenal function in neonatally estrogenized male mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355803"}
{"pmid": "4355804", "title": "Active transport of 131-I across the blood-brain barrier.", "content": "Active transport of 131-I across the blood-brain barrier. The ventricular space of rabbits was perfused with a low-viscosity silicone oil for the purpose of (1) collecting freshly secreted cerebrospinal fluid (c.s.f.) uninfluenced by diffusional exchanges with the brain and (2) studying passage of solutes from the blood into the brain, uncomplicated by exchanges with c.s.f. The freshly secreted c.s.f. appeared as fine droplets suspended in the less dense silicone, and accumulated at the bottom of the collected silicone. Studies on the penetration of (24)Na from blood into this fluid indicated that considerable exchanges with the brain had occurred between its secretion and collection, in spite of this method of collection. The second objective was attained, in that the exchanges between the freshly secreted fluid and the brain were quantitatively insufficient to affect the measure of kinetics of uptake by brain from the blood. In consequence, it was possible to demonstrate unequivocally that the increased uptake by brain of (131)I, when treated with perchlorate, was due to inhibition of an active process occurring across the blood-brain barrier. Other studies, involving ventriculo-cisternal perfusion with artificial c.s.f., lent further support to this concept. (131)I distribution is some 32% of the brain weight, a figure close to the ;chloride-space'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355804"}
{"pmid": "4355805", "title": "On the mechanism of halothane anaesthesia.", "content": "On the mechanism of halothane anaesthesia. 1. The effects of halothane on the evoked potentials of in vitro preparations of guinea-pig olfactory cortex were studied.2. The evoked potentials recorded from the cortical surface comprised an initial diphasic wave - the lateral olfactory tract (l.o.t.) compound action potential - followed by a negative wave of 1-3 mV amplitude and about 10 msec duration. Superimposed on the negative wave was a number of positive peaks. The negative wave has been identified as an extracellularly recorded, monosynaptic, excitatory post-synaptic potential (e.p.s.p.) and the positive peaks have been shown to reflect the discharge of the cortical cell population in response to the evoked e.p.s.p. and are therefore termed ;population spikes'.3. When halothane (0.4-1.5%) was added to the gas stream that superfused the surface of the preparation the evoked e.p.s.p.s became smaller in amplitude and the size of the population spikes diminished. The l.o.t. compound action potential was unaffected by these levels of halothane. Higher levels of halothane (above 2%) further reduced the amplitude of the evoked e.p.s.p.s, abolished the population spikes, decreased the amplitude of the l.o.t. compound action potential and slowed its time course. The effects of halothane on the evoked potentials were dose-related and were independent (after the first 10 min of treatment) of the duration of the exposure to halothane.4. The decrease in the size of the population spike caused by the exposure to halothane implied that transmission through the cortical relay had been impaired. This was also shown by the decrease in the evoked activity of units in the prepiriform cortex. Of eleven units, eight were depressed by halothane (0.5-1.5%) two were unaffected and one showed a transient increase in the number of spikes generated in response to a l.o.t. volley.5. Halothane (up to 1.5%) had no effect on the threshold of the l.o.t. fibres to electrical stimulation or on that of the post-synaptic cells to synaptic excitation.6. Post-tetanic potentiation and frequency potentiation of the evoked e.p.s.p.s were enhanced in the presence of 1% halothane.7. It is concluded that halothane reduces excitatory synaptic transmission not by an increase in the electrical threshold of the post-synaptic cells to synaptic excitation but by interference with the process of chemical transmission either by reducing the output of transmitter from the pre-synaptic nerve terminal or by reducing the sensitivity of the post-synaptic membrane to the released transmitter substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355805"}
{"pmid": "4355806", "title": "Effect of insulin and epinephrine on the carbohydrate metabolism and adenylate cyclase activity of rhesus fetal muscle.", "content": "Effect of insulin and epinephrine on the carbohydrate metabolism and adenylate cyclase activity of rhesus fetal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355806"}
{"pmid": "4355800", "title": "Suppression of growth of L cells in suspension culture by dibutyrl adenosine 3',5'-monophosphate.", "content": "Suppression of growth of L cells in suspension culture by dibutyrl adenosine 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355800"}
{"pmid": "4355807", "title": "Subcellular constituents of human placenta. I. Isolation and characterization of lysosomes from term tissue.", "content": "Subcellular constituents of human placenta. I. Isolation and characterization of lysosomes from term tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355807"}
{"pmid": "4355799", "title": "Inhibitory effect of streptonigrin on a murine sarcoma virus-induced tumor cell line (MSC) and selection of drug-resistant clones.", "content": "Inhibitory effect of streptonigrin on a murine sarcoma virus-induced tumor cell line (MSC) and selection of drug-resistant clones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355799"}
{"pmid": "4355801", "title": "Selective detachment of mitotic cells by hypotonic salt solution.", "content": "Selective detachment of mitotic cells by hypotonic salt solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355801"}
{"pmid": "4355810", "title": "Steroids and steroidases XX (1). Aggregation in aqueous solution of steroids with stigmastane type C-17 side chains and its influence on their enzymic transformations.", "content": "Steroids and steroidases XX (1). Aggregation in aqueous solution of steroids with stigmastane type C-17 side chains and its influence on their enzymic transformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355810"}
{"pmid": "4355811", "title": "Synthesis of 21-3H-corticosteroids.", "content": "Synthesis of 21-3H-corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355811"}
{"pmid": "4355809", "title": "Biosynthesis of steroids from cholesterol-14C by human adrenal carcinoma tissue.", "content": "Biosynthesis of steroids from cholesterol-14C by human adrenal carcinoma tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355809"}
{"pmid": "4355813", "title": "The renin axis in causation, prognosis and treatment of hypertensive disease.", "content": "The renin axis in causation, prognosis and treatment of hypertensive disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355813"}
{"pmid": "4355814", "title": "The carcinoembryonic antigen (CEA) in carcinomata of the stomach.", "content": "The carcinoembryonic antigen (CEA) in carcinomata of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355814"}
{"pmid": "4355817", "title": "Effect of ovarian hormones on lipid metabolism in different tissues of rats.", "content": "Effect of ovarian hormones on lipid metabolism in different tissues of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355817"}
{"pmid": "4355818", "title": "Effect of imidazole on the adrenal response to ACTH and to stress.", "content": "Effect of imidazole on the adrenal response to ACTH and to stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355818"}
{"pmid": "4355819", "title": "Investigations on the correlation between abnormalities of neuromuscular transmission due to some organophosphates and activity of acetylcholinesterase in the skeletal muscle.", "content": "Investigations on the correlation between abnormalities of neuromuscular transmission due to some organophosphates and activity of acetylcholinesterase in the skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355819"}
{"pmid": "4355821", "title": "The effects of prostaglandin F2 alpha on the structure and function of the rabbit ovary.", "content": "The effects of prostaglandin F2 alpha on the structure and function of the rabbit ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355821"}
{"pmid": "4355822", "title": "Morphological changes in the corpus luteum correlated with progestin levels in the rhesus monkey during early pregnancy.", "content": "Morphological changes in the corpus luteum correlated with progestin levels in the rhesus monkey during early pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355822"}
{"pmid": "4355823", "title": "Mouse bone collagenase. The effect of heparin on the amount of enzyme released in tissue culture and on the activity of the enzyme.", "content": "Mouse bone collagenase. The effect of heparin on the amount of enzyme released in tissue culture and on the activity of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355823"}
{"pmid": "4355825", "title": "Selective inactivation of the infectivity of freeze-dried Sendai virus by heat.", "content": "Selective inactivation of the infectivity of freeze-dried Sendai virus by heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355825"}
{"pmid": "4355824", "title": "Propionin B, an antiviral principle of propionibacteria.", "content": "Propionin B, an antiviral principle of propionibacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355824"}
{"pmid": "4355827", "title": "Influence of plasma on ACTH stimulated corticosterone production of isolated adrenal cells.", "content": "Influence of plasma on ACTH stimulated corticosterone production of isolated adrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355827"}
{"pmid": "4355820", "title": "Clinical pharmacology of sleep: a critical review of all-night electroencephalographic studies.", "content": "Clinical pharmacology of sleep: a critical review of all-night electroencephalographic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355820"}
{"pmid": "4355830", "title": "Rhabdoviruses.", "content": "Rhabdoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355830"}
{"pmid": "4355831", "title": "Viruses with double-stranded RNA genomes.", "content": "Viruses with double-stranded RNA genomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355831"}
{"pmid": "4355832", "title": "A spin-label study of the role of phospholipids in the regulation of membrane-bound microsomal enzymes.", "content": "A spin-label study of the role of phospholipids in the regulation of membrane-bound microsomal enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355832"}
{"pmid": "4355833", "title": "Studies of simian virus 40 DNA. VII. A cleavage map of the SV40 genome.", "content": "Studies of simian virus 40 DNA. VII. A cleavage map of the SV40 genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355833"}
{"pmid": "4355834", "title": "A map of simian virus 40 transcription sites expressed in productively infected cells.", "content": "A map of simian virus 40 transcription sites expressed in productively infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355834"}
{"pmid": "4355835", "title": "Letter: Electron microscopic observation of DNA condensates at low pH values.", "content": "Letter: Electron microscopic observation of DNA condensates at low pH values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355835"}
{"pmid": "4355836", "title": "Adenovirus isolation from recurrent oral ulcers.", "content": "Adenovirus isolation from recurrent oral ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355836"}
{"pmid": "4355829", "title": "Amoebiasis cutis.", "content": "Amoebiasis cutis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355829"}
{"pmid": "4355837", "title": "Discharge and a discharge group.", "content": "Discharge and a discharge group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355837"}
{"pmid": "4355838", "title": "Students learn to negotiate for role and demonstrate skill as group.", "content": "Students learn to negotiate for role and demonstrate skill as group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355838"}
{"pmid": "4355848", "title": "Correlation between the antiviral effect of interferon treatment and the inhibition of in vitro mRNA translation in noninfected L cells.", "content": "Correlation between the antiviral effect of interferon treatment and the inhibition of in vitro mRNA translation in noninfected L cells. When noninfected L-cell suspension cultures are treated with interferon (specific activities superior to 10(6) reference units per mg of protein), the cell-free cytoplasmic extracts obtained are inactive for the translation of exogenous natural mRNAs. The dose-response curve shows that comparable amounts of interferon are required to produce a 50% reduction of Mengo virus multiplication in vivo and Mengo RNA translation in vitro. With higher doses of interferon, Mengo RNA translation is completely abolished, while poly U translation and endogenous protein synthesis are only slightly affected. The inactivation of Mengo RNA translation is reversible; after removal of interferon, normal translation activity is regained together with the ability to support Mengo virus multiplication. Fractionation of the cell-free extracts shows that the effect is localized in the fraction which can be washed off the ribosomes by high salt. These results establish that interferon induces a block in genetic translation in noninfected L cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355848"}
{"pmid": "4355842", "title": "Preventive aspects of the comprehensive psychiatric service in USSR.", "content": "Preventive aspects of the comprehensive psychiatric service in USSR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355842"}
{"pmid": "4355840", "title": "Evaluating mental health status with a simplified rating scale.", "content": "Evaluating mental health status with a simplified rating scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355840"}
{"pmid": "4355850", "title": "Acquisition of sequences homologous to host DNA by closed circular simian virus 40 DNA. II. Further studies on the serial passage of virus clones.", "content": "Acquisition of sequences homologous to host DNA by closed circular simian virus 40 DNA. II. Further studies on the serial passage of virus clones. Three plaque isolates of SV40 strain 777 and 1 plaque isolate of strain 776 were grown to high-titer stocks and serially passaged, undiluted, in monkey BS-C-1 cells. In each case, the serial passaging procedure resulted in the accumulation of closed-circular SV40 DNA molecules containing covalently linked sequences homologous to reiterated host cell DNA (called substituted virus DNA). The relative yields, at a given passage level, of SV40 DNA with measurable homology to host DNA varied in different sets of serial passages, including passages of the same virus clone. More reproducible yields of substituted viral DNA progeny were obtained when the serial passaging procedure was initiated from earlier passages rather than from the original plaque-purified stock. Fractionation of closed-circular SV40 DNA molecules on alkaline sucrose gadients indicated that the majority of substituted virus DNA molecules are not plaque producers and are slightly smaller in size than plaque-forming DNA molecules which display no detectable homology to host DNA. Evidence that substituted SV40 DNA molecules replicate during serial undiluted passage was obtained from experiments which demonstrated (i) the presence of host sequences in replicative forms of the viral DNA and (ii) the incorporation of (3)H-thymidine into host sequences isolated from the mature substituted virus DNA molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355850"}
{"pmid": "4355841", "title": "The \"sectorization\" of comprehensive psychiatric services in France.", "content": "The \"sectorization\" of comprehensive psychiatric services in France.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355841"}
{"pmid": "4355849", "title": "Chromatographic analyses of isoaccepting tRNAs from avian myeloblastosis virus.", "content": "Chromatographic analyses of isoaccepting tRNAs from avian myeloblastosis virus. Avian myeloblastosis virus (AMV) 4S RNA was tested for amino acid acceptor activity for 18 of the 20 amino acids. A nonrandom distribution of viral tRNAs was found compared with tRNA from normal liver or from AMV-infected leukemic myeloblasts, confirming previous reports. Methionine and proline tRNAs were considerably enriched, whereas glutamic acid, glutamine, serine, tyrosine, and valine tRNAs were markedly depleted in AMV relative to homologous cellular tRNAs. The seven AMV tRNAs with the greatest amino acid acceptance capacities, which were in order methionine, proline, lysine, arginine, histidine, isoleucine, and threonine tRNAs, were compared with homologous tRNAs from leukemic myeloblasts and liver by reversed-phase 5 chromatography. Of the 25 isoaccepting chromatographic fractions identified, no tRNA species unique to AMV was detected. Only methionyl-tRNA showed a substantial quantitative variation in isoaccepting species compared with the host cell. Thus, viral selectivity for amino acid-specific tRNAs is not, generally, paralleled by selectivity for individual isoaccepting tRNA species. Qualitative differences in arginyl- and histidyl-tRNA isoaccepting species were discovered in virus and leukemic myeloblasts compared with liver. This indicates the existence of structural differences in these tRNA species which could be related to virus replication or expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355849"}
{"pmid": "4355839", "title": "Introduction of goal-oriented record keeping on an inpatient drug treatment setting.", "content": "Introduction of goal-oriented record keeping on an inpatient drug treatment setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355839"}
{"pmid": "4355847", "title": "A forced-choice test for selecting psychiatric personnel.", "content": "A forced-choice test for selecting psychiatric personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355847"}
{"pmid": "4355843", "title": "Meeting basic needs of the elderly.", "content": "Meeting basic needs of the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355843"}
{"pmid": "4355851", "title": "Acquisition of sequences homologous to host DNA by closed circular simian virus 40 DNA. 3. Host sequences.", "content": "Acquisition of sequences homologous to host DNA by closed circular simian virus 40 DNA. 3. Host sequences. A preparation of serially passaged simian virus 40 (SV40) DNA, in which at least 66% of the molecules contain covalently linked cellular DNA sequences, was digested to completion with the Hemophilus influenzae restriction endonuclease. Polyacrylamide gel electrophoresis of the digest showed that the majority of the cleavage products migrated as nine classes of fragments, each class defined by a particular molecular weight. These classes of fragments differ in molecular weight from the fragments produced by the action of the same enzyme on plaque-purified virus DNA. Three classes of fragments were present in less than equimolar amounts relative to the original DNA. The remaining six classes of fragments each contain more than one fragment per original DNA molecule. DNA-DNA hybridization analysis (using the filter method) of the isolated cleavage products demonstrated the presence of highly reiterated cell DNA sequences in two of the nine classes of fragments. A third class of fragments hybridized with high efficiency only to serially passaged SV40 DNA; the level of hybridization to plaque-purified virus DNA was low and there was essentially no hybridization with cell DNA immobilized on filters. It is suggested that this class of fragments contains unique host sequences. It was estimated that at least 27% of the sequences in the substituted SV40 DNA molecules studied are host sequences. The majority of these are probably of the nonreiterated type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355851"}
{"pmid": "4355846", "title": "The community mental health professional and the poor.", "content": "The community mental health professional and the poor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355846"}
{"pmid": "4355853", "title": "Separation of DNA sequences complementary to the RNA of avian myeloblastosis virus from chicken DNA by alkaline cesium chloride density sedimentation.", "content": "Separation of DNA sequences complementary to the RNA of avian myeloblastosis virus from chicken DNA by alkaline cesium chloride density sedimentation. Density gradient sedimentation in alkaline cesium chloride of DNA from normal chicken embryos or leukemic myeloblasts fragmented to a size of 13S revealed that the DNA sequences complementary to 70S avian myeloblastosis virus RNA sedimented in the high guanine plus cytosine region ahead of the main peak of cellular DNA. When the DNA was fragmented into pieces of 6.6S there was a broader distribution of the DNA sequences complementary to the viral RNA. This technique could be employed as a step towards the isolation of DNA copies of the entire viral RNA genome from the mass of host cellular DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355853"}
{"pmid": "4355845", "title": "Bacterial resistance to antibiotics.", "content": "Bacterial resistance to antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355845"}
{"pmid": "4355844", "title": "Speaking out: awash in freedom from hospitalization.", "content": "Speaking out: awash in freedom from hospitalization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355844"}
{"pmid": "4355854", "title": "Cleavage of poliovirus-specific polypeptide aggregates.", "content": "Cleavage of poliovirus-specific polypeptide aggregates. Zonal electrophoresis resolves two aggregates of poliovirus type 2 cytoplasmic polypeptides. The more negatively charged aggregate contains mainly noncapsid viral-specific polypeptides (NCVP) 2 and x, whereas the other consists of the capsid polypeptides (VP) 0, 1, 2, and 3 (VP0, VP1, VP2, VP3). After treatment with sodium deoxycholate (DOC), the aggregates sediment at 5 to 6S. Their electrophoretic mobilities are unaffected by DOC or RNase. The capsid polypeptide aggregate is similar in mobility to virions but can be converted to a faster electrophoretic form, resembling empty capsids, by heating. If infected HeLa cells are allowed to synthesize poliovirus polypeptides in the presence of iodoacetamide, no capsid polypeptides are produced, but rather NCVP1a (the precursor to capsid polypeptides) is accumulated, along with NCVP2 and NCVPx. When analyzed by electrophoresis and centrifugation, uncleaved NCVP1a migrates with the NCVP2-x aggregate. NCVP1a can be cleaved to capsid-like polypeptides in vitro by using extracts of infected cells, but not uninfected cells, indicating either a virus-specified protease or a cellular enzyme activated during infection. After cleavage of NCVP1a by infected cell extracts, the capsid polypeptides which are produced dissociate from the NCVP2-x complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355854"}
{"pmid": "4355852", "title": "Phosphorylation of animal virus proteins by a virion protein kinase.", "content": "Phosphorylation of animal virus proteins by a virion protein kinase. Compared with several other enveloped viruses, purified virions of frog virus 3 contained a relatively high activity of a protein kinase which catalyzed the phosphorylation of endogenous polypeptides or added substrate proteins. Virions also contained a phosphoprotein phosphatase activity which released phosphate covalently linked to proteins. It was possible to select reaction conditions where turnover of protein phosphoesters was minimal, as the phosphatase required Mn(2+) ions for activity whereas the protein kinase was active in the presence of Mg(2+) ions. Electrophoretic studies in polyacrylamide gels containing sodium dodecyl sulfate indicated that at least 10 of the virion polypeptides were phosphorylated in the in vitro protein kinase reaction. Characterization of these phosphoproteins demonstrated that the phosphate was incorporated predominantly in a phosphoester linkage with serine residues. The protein kinase was solubilized by disrupting purified virions with a nonionic detergent in a high-ionic-strength buffer and was separated from many of the virion substrate proteins by zonal centrifugation in glycerol gradients. The partially purified protein kinase would phosphorylate polypeptides of many different animal viruses, and maximal activity was not dependent on added cyclic nucleotides. These properties distinguished the virion protein kinase from a well characterized cyclic AMP-dependent protein kinase which phosphorylated viral proteins only to a small extent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355852"}
{"pmid": "4355828", "title": "A new dental, ocular and cutaneous syndrome.", "content": "A new dental, ocular and cutaneous syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355828"}
{"pmid": "4355855", "title": "RNA synthesis in temperature-sensitive mutants of vesicular stomatitis virus.", "content": "RNA synthesis in temperature-sensitive mutants of vesicular stomatitis virus. T-particle-free stocks of temperature-sensitive mutants representing the four Glasgow complementation groups of the Indiana serotype of vesicular stomatitis virus were used to study RNA synthesis at the permissive and nonpermissive temperatures of 31 and 39 C, respectively. Mutants selected from the four Glasgow complementation groups were characterized on the basis of particle and ribonucleoprotein formation. Intracellular RNAs were further characterized by polyacrylamide gel electrophoresis. ts G22 (group II) and ts G41 (group IV), previously characterized as RNA negative at the nonpermissive temperature, synthesized low levels of RNA which could not be attributed to contaminating levels of revertants. Furthermore, the levels of synthesis could not be reduced by the addition of cycloheximide. These data suggest that ts G22 (group II) and ts G41 (group IV) contain a thermally stable, virion-encapsidated transcriptase, but fail to amplify RNA synthesis due to a thermally labile function presumably necessary for the synthesis of viral RNA. ts G31, a group III mutant, synthesized intracellular RNA at amplified levels at the nonpermissive temperature. Intracellular ribonucleoprotein complexes were isolated in copious amounts; however, no particles corresponding in size to finished virions were observed. These data suggest a thermally labile maturation factor or envelope associated structural protein to be defective in ts G31 (group III). ts G11 (group 1) showed no detectable RNA synthesis at the nonpermissive temperature. These data suggest ts G11 (group I) contains a thermally labile component involved in early transcription. This group may contain a number of mutants defective in different components of the transcription apparatus, which may not complement in vivo because of the physical improbability of subunit exchange between virion particles of the incoming inoculum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355855"}
{"pmid": "4355856", "title": "Gel electrophoresis of avian leukosis and sarcoma viral RNA in formamide: comparison with other viral and cellular RNA species.", "content": "Gel electrophoresis of avian leukosis and sarcoma viral RNA in formamide: comparison with other viral and cellular RNA species. Class a and class b 30 to 40S RNA subunits obtained by heat dissociation from the 60 to 70S RNA complex of avian tumor viruses were compared with several RNA standards by electrophoresis in formamide-polyacrylamide gels. Class a RNA was found to have a lower electrophoretic mobility and hence probably a higher molecular weight than class b RNA. The absolute molecular weight of class a and b RNA could not be determined with accuracy, because the relationship between logarithm of molecular weight and mobility of the RNA standards was not linear. The size of class a RNA fell into the range of 2.4 x 10(6) to 3.4 x 10(6) daltons and that of class b into the range of 2.2 x 10(6) to 2.9 x 10(6) daltons, depending on the standards used. The possible biological significance of this difference is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355856"}
{"pmid": "4355858", "title": "Hydroxyurea-induced accumulation of short fragments during polyoma DNA replication. II. Behavior during incubation of isolated nuclei.", "content": "Hydroxyurea-induced accumulation of short fragments during polyoma DNA replication. II. Behavior during incubation of isolated nuclei. The synthesis of polyoma DNA was studied in isolated nuclei from hydroxyurea-inhibited 3T6 cells infected with polyoma virus. During incubation of nuclei under conditions suitable for polyoma DNA synthesis in vitro, the short DNA fragments with a sedimentation coefficient of 4S formed in vivo (hydroxyurea fragments) became associated with preformed, replicating DNA strands. Centrifugation in dye-buoyant density gradients showed that the fragments formed part of the structure of the replicative intermediate of polyoma DNA. The proportion of \"young\" replicative intermediates was larger after hydroxyurea inhibition than in uninhibited controls. Hydroxyurea fragments appear to be closely related to the 4S fragments formed as normal intermediates during discontinuous synthesis of polyoma DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355858"}
{"pmid": "4355859", "title": "Envelope of mouse mammary tumor virus studied by freeze-etching and freeze-fracture techniques.", "content": "Envelope of mouse mammary tumor virus studied by freeze-etching and freeze-fracture techniques. As part of a study of the cell surface changes associated with the production of murine mammary tumor virus, the structure of the envelope of this virus has been examined by using freeze-fracture techniques. Both fracture and deep-etch surfaces were examined. The fracture faces contain 10-nm spheres comparable to those observed on fractured plasma membranes, although fewer in number. Surfaces exposed by etching possess a highly regular hexagonal array of pits 25 nm apart. By examining freeze-fracture and freeze-etch preparations of virus with ferritin covalently bound to its surface, it has been determined that the surface exposed by etching is the outer surface of the virus. The pitted exterior surface of the mammary tumor virus appears to be a unique surface structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355859"}
{"pmid": "4355857", "title": "Hydroxyurea-induced accumulation of short fragments during polyoma DNA replication. I. Characterization of fragments.", "content": "Hydroxyurea-induced accumulation of short fragments during polyoma DNA replication. I. Characterization of fragments. Hydroxyurea treatment of 3T6 mouse fibroblast cells infected with polyoma virus resulted within 15 min in more than a 20-fold reduction of the rate of both viral and cellular DNA synthesis. After the initial rapid inhibition, the rate of DNA synthesis remained essentially constant for at least 2 h. In the inhibited cells viral DNA accumulated as short chains with a sedimentation coefficient of about 4S (hydroxyurea fragments). A variable proportion of these fragments was released from the template strands when the viral DNA was extracted by the Hirt procedure. Reannealing experiments demonstrated that hydroxyurea fragments were polyoma-specific and probably synthesized on both parental strands at the replication forks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355857"}
{"pmid": "4355860", "title": "Human papovavirus, BK strain: biological studies including antigenic relationship to simian virus 40.", "content": "Human papovavirus, BK strain: biological studies including antigenic relationship to simian virus 40. Some of the properties of a new human papovavirus, BK, have been examined. Host range studies of BK virus (BKV) showed human cells to be more sensitive to infection than monkey cells; human fetal brain cells appear to be highly sensitive to BKV, with the production of extensive cytopathology characterized by cytoplasmic vacuolization. The hemagglutinin of BKV is associated with the virion and is resistant to ether or heating at 56 C for 30 min. Fluorescent antibody as well as neutralization tests indicated antigenic similarities between simian virus 40 (SV40) and BKV. Cells undergoing lytic infection with BKV synthesized intranuclear T antigen(s) which reacted with SV40 T antibody demonstrable by immunofluorescence. However, BKV did not appear to induce SV40 transplantation antigens in transplantation-resistance tests. Evidence was obtained that BKV was present in humans prior to the widespread use of polio vaccines, thus ruling out the possibility that BKV is an SV40-related monkey virus, introduced into the human population by accidental contamination of poliovirus vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355860"}
{"pmid": "4355861", "title": "Use of nondefective adenovirus-simian virus 40 hybrids for mapping the simian virus 40 genome.", "content": "Use of nondefective adenovirus-simian virus 40 hybrids for mapping the simian virus 40 genome. A series of viable recombinants between adenovirus 2 (Ad2) and simian virus 40 (SV40) (nondefective Ad2-SV40 hybrids) have been isolated. The members of this series (designated Ad2(+)ND(1) through Ad2(+)ND(5)) differ from one another in the early SV40-specific antigens and the SV40-specific RNA species which they induce in infected cells. They also contain different amounts of SV40 DNA as shown by RNA-DNA hybridization techniques. We have examined the structure of the DNA molecules from these hybrids, using electron microscope heteroduplex mapping techniques. Each hybrid was found to contain a single segment of SV40 DNA of characteristic size covalently inserted at a unique location in the adenovirus 2 DNA molecule. The SV40 segments of the various hybrids formed an overlapping series with a common end point. When the results of the electron microscopic study were combined with data on antigen induction, it was found that a self-consistent map could be constructed which related specific regions of the SV40 genome to the induction of specific antigens. The order of these early SV40 antigen inducing regions in the SV40 DNA segments contained in the nondefective hybrids is: U antigen, tumor specific transplantation antigen, and T antigen with the U antigen region being nearest the common end point.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355861"}
{"pmid": "4355862", "title": "Mapping of simian virus 40 early functions on the viral chromosome.", "content": "Mapping of simian virus 40 early functions on the viral chromosome. The simian virus 40 (SV40) DNA segment in the nondefective adenovirus 2-SV40 hybrid, Ad2(+)ND(4), is colinear with the segment between 0.11 and 0.59 SV40 fractional length from the site at which the R(1) restriction endonuclease cleaves SV40 DNA. This specifies the region of the SV40 DNA molecule which induces the early SV40 antigens: U antigen, tumor specific transplantation antigen, and T antigen. A variant of Ad2(+)ND(4), called Ad2(+)ND(4del), was found which has a deletion of the DNA segment between 0.50 and 0.57 SV40 fractional length from the R(1) endonuclease cleavage point.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355862"}
{"pmid": "4355863", "title": "Growth of pseudotypes of vesicular stomatitis virus with N-tropic murine leukemia virus coats in cells resistant to N-tropic viruses.", "content": "Growth of pseudotypes of vesicular stomatitis virus with N-tropic murine leukemia virus coats in cells resistant to N-tropic viruses. Formation of pseudotypes between murine RNA tumor viruses and vesicular stomatitis virus (VSV) has been confirmed. Pseudotypes of VSV genomes coated by the surface envelope from an N-tropic tumor virus grew equally well in cells homozygous for either the Fv-1(n) or Fv-1(b) alleles. Therefore, the product of the Fv-1 locus, which restricts growth of murine RNA tumor viruses, must act on an intracellular aspect of tumor virus replication, a step after attachment and penetration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355863"}
{"pmid": "4355865", "title": "Improved technique for the isolation of temperature-sensitive mutants of foot-and-mouth disease virus.", "content": "Improved technique for the isolation of temperature-sensitive mutants of foot-and-mouth disease virus. An improved temperature-shift selection and screening method is described for the isolation of temperature-sensitive mutants of foot and mouth disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355865"}
{"pmid": "4355864", "title": "Proposed nomenclature for mutants of adenoviruses.", "content": "Proposed nomenclature for mutants of adenoviruses. In accord with the nomenclature proposed for mutants of simian virus 40 the same rules, with minor modifications, are recommended for naming mutants of adenoviruses. It is further suggested that these rules, which pertain to a system of classification based primarily upon complementation analysis, also be applied to mutants of other DNA-containing animal viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355864"}
{"pmid": "4355867", "title": "A rapid and reproducible homogenization procedure for the isolation of plasma membranes from rat liver.", "content": "A rapid and reproducible homogenization procedure for the isolation of plasma membranes from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355867"}
{"pmid": "4355868", "title": "An inexpensive apparatus facilitating the storage of oxygen sensitive compounds.", "content": "An inexpensive apparatus facilitating the storage of oxygen sensitive compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355868"}
{"pmid": "4355869", "title": "Preparative electrophoresis of living mammalian cells in a stationary ficoll gradient.", "content": "Preparative electrophoresis of living mammalian cells in a stationary ficoll gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355869"}
{"pmid": "4355871", "title": "Chlorphentermine-induced ultrastructural changes in liver tissues of four animal species.", "content": "Chlorphentermine-induced ultrastructural changes in liver tissues of four animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355871"}
{"pmid": "4355873", "title": "Vinblastine-induced paracrystals and unusually large microtubules (macrotubules) in rat renal cells.", "content": "Vinblastine-induced paracrystals and unusually large microtubules (macrotubules) in rat renal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355873"}
{"pmid": "4355874", "title": "Intercellular contact in the unincubated chick embryo.", "content": "Intercellular contact in the unincubated chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355874"}
{"pmid": "4355875", "title": "Fine structure of the developing spore of Nosema apis Zander.", "content": "Fine structure of the developing spore of Nosema apis Zander.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355875"}
{"pmid": "4355876", "title": "Fluorescence histochemical and ultrastructural observations on the effects of intravenous injections of vinblastine on noradrenergic nerves.", "content": "Fluorescence histochemical and ultrastructural observations on the effects of intravenous injections of vinblastine on noradrenergic nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355876"}
{"pmid": "4355878", "title": "Structure and innervation of the pineal gland of the rabbit, Oryctolagus cuniculus (L.). II. An electron microscopic investigation of the pinealocytes.", "content": "Structure and innervation of the pineal gland of the rabbit, Oryctolagus cuniculus (L.). II. An electron microscopic investigation of the pinealocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355878"}
{"pmid": "4355877", "title": "Effects of parathyroid hormone on osteoclasts in vivo. An ultrastructural and histochemical study.", "content": "Effects of parathyroid hormone on osteoclasts in vivo. An ultrastructural and histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355877"}
{"pmid": "4355880", "title": "Morphologic observations of brain tumors in PD4 hamsters induced by four strains of avian sarcoma virus.", "content": "Morphologic observations of brain tumors in PD4 hamsters induced by four strains of avian sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355880"}
{"pmid": "4355879", "title": "Histological and ultrastructural observations on wound healing in the freshwater pulmonate Lymnaea stagnalis.", "content": "Histological and ultrastructural observations on wound healing in the freshwater pulmonate Lymnaea stagnalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355879"}
{"pmid": "4355881", "title": "Pseudocroup with stridor.", "content": "Pseudocroup with stridor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355881"}
{"pmid": "4355882", "title": "Ultrastructural study of the human anterior pituitary. Preliminary results.", "content": "Ultrastructural study of the human anterior pituitary. Preliminary results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355882"}
{"pmid": "4355884", "title": "Spontaneous and light-induced compound action potentials in the isolated eye of Aplysia: initiation and synchronization.", "content": "Spontaneous and light-induced compound action potentials in the isolated eye of Aplysia: initiation and synchronization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355884"}
{"pmid": "4355883", "title": "Effects of mammalian corticotrophin on the ultrastructure of presumptive interrenal cells in the opisthonephros of the lamprey, Petromyzon marinus L.", "content": "Effects of mammalian corticotrophin on the ultrastructure of presumptive interrenal cells in the opisthonephros of the lamprey, Petromyzon marinus L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355883"}
{"pmid": "4355885", "title": "Dose effects of cortisol on single unit activity in hypothalamus, reticular formation and hippocampus of freely behaving rats correlated with plasma steroid levels.", "content": "Dose effects of cortisol on single unit activity in hypothalamus, reticular formation and hippocampus of freely behaving rats correlated with plasma steroid levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355885"}
{"pmid": "4355886", "title": "Microelectrophoretic studies on the depressant action of HA-966 on chemically and synaptically excited neurones in the cat cerebral cortex and cuneate nucleus.", "content": "Microelectrophoretic studies on the depressant action of HA-966 on chemically and synaptically excited neurones in the cat cerebral cortex and cuneate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355886"}
{"pmid": "4355888", "title": "Equivalence of synaptic and injected current in determining the membrane potential trajectory during motoneuron rhythmic firing.", "content": "Equivalence of synaptic and injected current in determining the membrane potential trajectory during motoneuron rhythmic firing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355888"}
{"pmid": "4355887", "title": "Effects of prostaglandins E1, E2 and F2a on cyclic AMP levels in brain in vivo.", "content": "Effects of prostaglandins E1, E2 and F2a on cyclic AMP levels in brain in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355887"}
{"pmid": "4355889", "title": "Masseteric reflex response to reticular stimulation reverses during active sleep compared with wakefulness or quiet sleep.", "content": "Masseteric reflex response to reticular stimulation reverses during active sleep compared with wakefulness or quiet sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355889"}
{"pmid": "4355890", "title": "High affinity uptake of cyclic AMP in rat brain slices.", "content": "High affinity uptake of cyclic AMP in rat brain slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355890"}
{"pmid": "4355891", "title": "Electron paramagnetic resonance (34 and 55 GHz) studies of hemoproteins.", "content": "Electron paramagnetic resonance (34 and 55 GHz) studies of hemoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355891"}
{"pmid": "4355892", "title": "Synthesis of glycerol-1,3-diphosphonic acid.", "content": "Synthesis of glycerol-1,3-diphosphonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355892"}
{"pmid": "4355893", "title": "Nucleotide clusters in deoxyribonucleic acids. 8. The pyrimidine oligonucleotides of bacteriophage S13 wild type DNA.", "content": "Nucleotide clusters in deoxyribonucleic acids. 8. The pyrimidine oligonucleotides of bacteriophage S13 wild type DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355893"}
{"pmid": "4355895", "title": "Amebiasis: a ten-year review of clinical and epidemiological progress in the Saskatchewan endemic area.", "content": "Amebiasis: a ten-year review of clinical and epidemiological progress in the Saskatchewan endemic area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355895"}
{"pmid": "4355897", "title": "Serum phospholipids in children with familial hypercholesterolaemia.", "content": "Serum phospholipids in children with familial hypercholesterolaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355897"}
{"pmid": "4355899", "title": "A role for ferritin in the regulation of iron metabolism.", "content": "A role for ferritin in the regulation of iron metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355899"}
{"pmid": "4355898", "title": "Pseudomonas bacterial endocarditis. A case report.", "content": "Pseudomonas bacterial endocarditis. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355898"}
{"pmid": "4355900", "title": "Dogfish lactate dehydrogenase. The stereochemistry of hydrogen transfer.", "content": "Dogfish lactate dehydrogenase. The stereochemistry of hydrogen transfer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355900"}
{"pmid": "4355901", "title": "The presence of lactic acid in purified lactate dehydrogenase.", "content": "The presence of lactic acid in purified lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355901"}
{"pmid": "4355902", "title": "Inactivation of ADH from yeast and GAPDH from rabbit muscle by structural analogues of NAD.", "content": "Inactivation of ADH from yeast and GAPDH from rabbit muscle by structural analogues of NAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355902"}
{"pmid": "4355904", "title": "A study on the cleavage site specificity of the endonuclease associated with purified simian virus 40 particles.", "content": "A study on the cleavage site specificity of the endonuclease associated with purified simian virus 40 particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355904"}
{"pmid": "4355905", "title": "Studies on the metabolism of cyclic nucleotides by the toad bladder: the metabolic products of cAMP.", "content": "Studies on the metabolism of cyclic nucleotides by the toad bladder: the metabolic products of cAMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355905"}
{"pmid": "4355906", "title": "The production of cIMP by toad bladder, and its effects on transport of water and salt.", "content": "The production of cIMP by toad bladder, and its effects on transport of water and salt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355906"}
{"pmid": "4355907", "title": "Butanol-soluble glycosyl transferases in Klebsiella aerogenes.", "content": "Butanol-soluble glycosyl transferases in Klebsiella aerogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355907"}
{"pmid": "4355908", "title": "Cytochrome c (553, Chlorobium thiosulfatophilum) is a sulphide-cytochrome c reductase.", "content": "Cytochrome c (553, Chlorobium thiosulfatophilum) is a sulphide-cytochrome c reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355908"}
{"pmid": "4355909", "title": "The influence of Mg2+-adenine nucleotide ratios and absolute concentration of Mg2+-adenine nucleotide on the observed velocity of some kinase reactions.", "content": "The influence of Mg2+-adenine nucleotide ratios and absolute concentration of Mg2+-adenine nucleotide on the observed velocity of some kinase reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355909"}
{"pmid": "4355910", "title": "Influence of uncouplers on succinate-cytochrome c reductase.", "content": "Influence of uncouplers on succinate-cytochrome c reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355910"}
{"pmid": "4355911", "title": "Distribution of insulin receptor sites among liver plasma membrane subfractions.", "content": "Distribution of insulin receptor sites among liver plasma membrane subfractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355911"}
{"pmid": "4355912", "title": "The chemotactic effect of cyclic nucleotides with substitutions in the base ring.", "content": "The chemotactic effect of cyclic nucleotides with substitutions in the base ring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355912"}
{"pmid": "4355913", "title": "Action of human skin collagenase on cartilage collagen.", "content": "Action of human skin collagenase on cartilage collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355913"}
{"pmid": "4355914", "title": "Purification by affinity chromatography of thermostable glyceraldehyde 3-phosphate dehydrogenase from Thermus aquaticus.", "content": "Purification by affinity chromatography of thermostable glyceraldehyde 3-phosphate dehydrogenase from Thermus aquaticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355914"}
{"pmid": "4355915", "title": "Formation of guanosine tetraphosphate (magic spot I) in homologous and heterologous systems.", "content": "Formation of guanosine tetraphosphate (magic spot I) in homologous and heterologous systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355915"}
{"pmid": "4355916", "title": "Depolarization induced calcium release from sarcoplasmic reticulum membrane fragments by changing ionic environment.", "content": "Depolarization induced calcium release from sarcoplasmic reticulum membrane fragments by changing ionic environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355916"}
{"pmid": "4355917", "title": "Does formylation of initiator tRNA act as a regulatory signal in E. coli?", "content": "Does formylation of initiator tRNA act as a regulatory signal in E. coli?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355917"}
{"pmid": "4355919", "title": "Nutritional correlates of child development in Southern Tunisia. 3. Skeletal growth and maturation.", "content": "Nutritional correlates of child development in Southern Tunisia. 3. Skeletal growth and maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355919"}
{"pmid": "4355920", "title": "Collagenase activity in cutaneous scars.", "content": "Collagenase activity in cutaneous scars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355920"}
{"pmid": "4355921", "title": "On the mechanism of radioprotection by cysteamine. II. The significance of cyclic 3',5'-AMP for the cysteamine-induced radioprotective effects in white mice.", "content": "On the mechanism of radioprotection by cysteamine. II. The significance of cyclic 3',5'-AMP for the cysteamine-induced radioprotective effects in white mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355921"}
{"pmid": "4355922", "title": "Letter: E.s.r. studies on gamma-irradiated TAN (triacetoneamine n-oxyl) radicals.", "content": "Letter: E.s.r. studies on gamma-irradiated TAN (triacetoneamine n-oxyl) radicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355922"}
{"pmid": "4355923", "title": "A rapid technique for obtaining one-step or multi-step antibiotic resistant mutants employing mutator strains of Escherichia coli K12.", "content": "A rapid technique for obtaining one-step or multi-step antibiotic resistant mutants employing mutator strains of Escherichia coli K12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355923"}
{"pmid": "4355924", "title": "Mitochondrial biogenesis during differentiation of Artemia salina cysts.", "content": "Mitochondrial biogenesis during differentiation of Artemia salina cysts. Mitochondria isolated from cysts of Artemia salina (brine shrimp) were found to be devoid of cristae and to possess a low respiratory capability. Hydration of the cysts induces marked biochemical and morphological changes in the mitochondria. Their biogenesis proceeds in two stages. The first stage is completed within 1 h and is characterized by a rapid increase in the respiratory capability of the mitochondria, their cytochrome oxidase, cytochrome b, cytochrome c and perhaps some morphological changes. In the second stage there is an increase in the protein-synthesizing capacity of the mitochondria as well as striking changes in mitochondrial morphology leading to the formation of cristae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355924"}
{"pmid": "4355925", "title": "Antivirals. 1. 2-(Alpha-hydroxybenzyl)imidazo(4,5-C)pyridine.", "content": "Antivirals. 1. 2-(Alpha-hydroxybenzyl)imidazo(4,5-C)pyridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355925"}
{"pmid": "4355926", "title": "Iodination of estrogen receptors in rat uterine eosinophils.", "content": "Iodination of estrogen receptors in rat uterine eosinophils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355926"}
{"pmid": "4355927", "title": "Effect of ampicillin treatment on the urinary excretion of estriol conjugates in pregnancy.", "content": "Effect of ampicillin treatment on the urinary excretion of estriol conjugates in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355927"}
{"pmid": "4355929", "title": "Hydroxyapatite chromatography and formamide denaturation of adenovirus DNA.", "content": "Hydroxyapatite chromatography and formamide denaturation of adenovirus DNA. Denatured adenovirus DNA was retained by hydroxyapatite columns under conditions generally used for selective retention of double-stranded DNA, probably due to several partially complementary sequences within single-stranded DNA. It was found that addition of formamide reduced the fraction of sonically treated, denatured adenovirus DNA bound to hydroxyapatite from about 30% to less than 1%. This led to a study of the effect of formamide on the melting temperature (T(m)) of double-stranded DNA in solution or bound to hydroxyapatite. The T(m) of DNA decreases 0.56 C/1% formamide, a value determined in buffered solutions with purified formamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355929"}
{"pmid": "4355928", "title": "Oncogenic transformation of hamster embryo cells after exposure to inactivated herpes simplex virus type 1.", "content": "Oncogenic transformation of hamster embryo cells after exposure to inactivated herpes simplex virus type 1. The in vitro transformation of hamster embryo fibroblasts by herpes simplex virus type 1 (HSV-1) after exposure of the virus to UV irradiation is described. Cell transformation was induced by 2 out of 12 strains of HSV-1 that were tested for transforming potential. Cells transformed by the KOS strain of HSV-1 were not oncogenic when injected into newborn Syrian hamsters. However, cells transformed by HSV-1 strain 14-012 induced tumors in 47% of the newborn hamsters injected. HSV-specific antigens were found in the cytoplasm of cells transformed by both virus strains. Sera from tumor-bearing hamsters contained HSV-1- and HSV-2-neutralizing antibodies as well as antibodies which reacted specifically with HSV antigens by the indirect immunofluorescence technique. Hamster oncornavirus antigens were not detected by immunofluorescence methods. These observations represent the first evidence of the oncogenic potential of HSV-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355928"}
{"pmid": "4355930", "title": "RNA synthesis by vesicular stomatitis virus and a small plaque mutant: effects of cycloheximide.", "content": "RNA synthesis by vesicular stomatitis virus and a small plaque mutant: effects of cycloheximide. The synthesis of viral RNA by wild-type vesicular stomatitis virus (L(1)VSV) and a small, plaque-size mutant (S(2)VSV) was studied in vitro and in chicken embryo (CE) and mouse L-cell cultures. Virus-specific RNA synthesized in CE or L cells infected with either L(1) or S(2)VSV at low multiplicity was of the same size classes, 12 to 15S, 28S, and 38S. The major differences were in the proportion of RNA produced of each size class. L(1)VSV always synthesized larger proportions of 38S RNA, and S(2)VSV produced larger proportions of 12 to 15S RNA. Both S(2) and L(1)VSV exhibited RNA transcriptase activity in vitro and in cell culture. The products of the in vitro reaction were the same, 12 to 15S for both. The products of the virion-associated transcriptase in CE or L-cell cultures in the presence of cycloheximide were also the same for both viruses but differed from the in vitro products in that 28S and 12 to 15S RNA were made. The effects of addition of cycloheximide at various times after infection demonstrated that new protein synthesis is required early (0-2 h) for both S(2) and L(1)VSV to initiate and maintain the normal rate of viral RNA synthesis. However, the overall rate of RNA synthesis in L(1)VSV infections became independent of protein synthesis after 2 h whereas the rate in S(2)VSV infections did not. With either virus, synthesis of 38S RNA did not occur in the absence of protein synthesis. Moreover, continuous 38S RNA production required continuous protein synthesis. Production of 38S RNA ceased within 30 min after addition of cycloheximide to S(2) (-) or L(1)VSV-infected CE or L cells that had already begun to synthesize the 38S form. The cycloheximide-induced cessation of 38S RNA synthesis was accompanied by a marked increase in production of 12 to 15S and 28S RNA in L(1)VSV-infected cells, but no increase in synthesis of small RNA species occurred in S(2)VSV-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355930"}
{"pmid": "4355932", "title": "Mechanism of oncogenic transformation by Rous sarcoma virus. 3. Role of proviral DNA in morphologic conversion of chicken embryo fibroblasts.", "content": "Mechanism of oncogenic transformation by Rous sarcoma virus. 3. Role of proviral DNA in morphologic conversion of chicken embryo fibroblasts. Multiplication of Rous sarcoma virus and morphological conversion of chicken embryo fibroblasts are mediated by a DNA provirus. The role of the provirus in induction of morphological conversion has been shown by experiments of light inactivation of bromodeoxyuridine (BUdR)-sensitized proviral DNA. In the experiments reported here, inactivation of focus formation by BUdR and light could be obtained in cells in which the ability to produce virus has become resistant to X irradiation. This property is considered here to reflect the integrated state of the provirus. These experiments indicate that the role of proviral DNA extends beyond induction of morphological conversion and that an intact provirus is required for the maintenance of the transformed state. These experiments also indicate that no irreversible process leading to morphological conversion is initiated by a nonintegrated or by an integrated provirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355932"}
{"pmid": "4355931", "title": "In vitro protein-synthesizing activity of vesicular stomatitis virus-infected cell extracts.", "content": "In vitro protein-synthesizing activity of vesicular stomatitis virus-infected cell extracts. Crude cytoplasmic extracts from vesicular stomatitis virus (VSV)-infected HeLa cells incorporate radioactive amino acids into hot trichloroacetic acid-precipitable material linearly for 10 to 20 min. The material synthesized in vitro corresponds in molecular weight to four of the five VSV structural proteins. However, synthesis of the viral glycoprotein (G) is significantly reduced, whereas the relative amounts of viral structural proteins L and NS synthesized are increased compared with the ratio of the proteins found in the virion. Fractionation of a VSV-infected crude cytoplasmic extract into a cytoplasmic pellet (20,000 x g for 30 min) and a cytoplasmic supernatant results in a significant reduction in protein synthesizing activity of both fractions, although both contain polysomes. The products synthesized by a cytoplasmic supernatant-directed system included all the VSV structural proteins except the glycoprotein, whereas in an in vitro system directed by the cytoplasmic pellet there is a marked reduction in synthesis of the nucleoprotein (N) and also a small relative increase in synthesis of the glycoprotein. Addition of uninfected, preincubated HeLa or L-cell S10 or a HeLa ribosomal fraction to the VSV-infected cytoplasmic pellet results in a 30- to 60-fold stimulation of (35)S-methionine incorporation. However, these uninfected extracts do not stimulate (35)S-methionine incorporation by the infected crude cytoplasmic extract or the cytoplasmic supernatant. The products synthesized by the stimulated cytoplasmic pellet now include sizeable amounts of the glycoprotein in addition to the other VSV structural proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355931"}
{"pmid": "4355933", "title": "Polypeptide composition of poliovirions, naturally occurring empty capsids, and 14S precursor particles.", "content": "Polypeptide composition of poliovirions, naturally occurring empty capsids, and 14S precursor particles. The three serotypes of poliovirus were compared with respect to their polypeptide composition. Type 1, 2, and 3 strains were clearly different from each other in the electrophoretic mobilities of their larger structural polypeptides. Some of the viral polypeptides formerly identified as single peaks (e.g., VP 2) were shown to contain multiple components, indicating that purified virions contain at least six polypeptides. Three type 1 strains were indistinguishable in their viral polypeptides. A quantitative estimate was made of the polypeptide composition of the type 1 Mahoney poliovirion, as well as of naturally occurring empty capsids and 14S precursor particles. The data are discussed in light of the antigenic differences among polioviruses and the possible modes of virion morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355933"}
{"pmid": "4355935", "title": "Characterization of the low-molecular-weight RNAs associated with the 70S RNA of Rous sarcoma virus.", "content": "Characterization of the low-molecular-weight RNAs associated with the 70S RNA of Rous sarcoma virus. Two low-molecular-weight RNAs are associated with the 70S RNA complex of Rous sarcoma virus: a previously described 4S RNA and a newly identified 5S RNA. The 4S RNA constitutes 3 to 4% of the 70S RNA complex or the equivalent of 12 to 20 molecules per 70S RNA. It exhibits a number of structural properties characteristic of transfer RNA as revealed by two-dimensional electrophoresis of oligonucleotides obtained from a T1 ribonuclease digest of the 4S RNA species. The 5S RNA is approximately 120 nucleotides in length, constitutes 1% of the 70S RNA complex or the equivalent of 3 to 4 molecules per molecules of 70S RNA, and is identical in nucleotide composition and structure to 5S RNA from uninfected chicken embryo fibroblasts. Melting studies indicate that the 5S RNA is released from the 70S RNA complex at the same temperature required to dissociate 70S RNA into its constituent 35S subunits. In contrast, greater than 80% of the 4S RNA is released from 70S RNA prior to its conversion into subunits. The possible biological significance of these 70S-associated RNAs is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355935"}
{"pmid": "4355934", "title": "Membrane proteins of uninfected and Rous sarcoma virus- transformed avian cells.", "content": "Membrane proteins of uninfected and Rous sarcoma virus- transformed avian cells. A method for preparing large membrane fragments and cell ghosts was developed for uninfected and Rous sarcoma virus-transformed chicken embryo fibroblasts in culture. Membrane proteins were analyzed by electrophoresis in acrylamide gels containing sodium dodecyl sulfate. A major amino-acid-containing component of uninfected cell membranes was greatly diminished in amount or absent in membranes of virus-transformed cells. This component, called MP-1, had an electrophoretic mobility in sodium dodecyl sulfate-containing gels similar to that of a protein of a mol wt of 1.42 x 10(5). MP-1 was not altered by changes in cell growth rate or in cells infected with the nontransforming virus RAV-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355934"}
{"pmid": "4355938", "title": "The use of estrogen as a postcoital contraceptive in North Carolina--trick or treatment.", "content": "The use of estrogen as a postcoital contraceptive in North Carolina--trick or treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355938"}
{"pmid": "4355936", "title": "Isolation of mutants of bacteriophage T4 unable to induce thymidine kinase activity.", "content": "Isolation of mutants of bacteriophage T4 unable to induce thymidine kinase activity. New mutants of T4 have been isolated by using a strain of Escherichia coli lacking thymidine kinase activity. These T4 mutants, designated tk, are able to grow on this E. coli strain under light on plates containing 5-bromodeoxyuridine and were all found to be unable to induce thymidine kinase (ATP: thymidine 5'-phosphotransferase, EC 2.7.1.21). All of these tk mutants fall into one complementation group which maps just to the right of rI on the standard T4 genetic map, far from most other genes coding for enzymes involved in pyrimidine metabolism. The tk mutants grow as well as wild-type T4, indicating that thymidine kinase is a non-essential enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355936"}
{"pmid": "4355940", "title": "Long term survivor in metastatic colonic carcinoma to the brain.", "content": "Long term survivor in metastatic colonic carcinoma to the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355940"}
{"pmid": "4355941", "title": "Effects of sex hormones on sleep patterns of male rats gonadectomized in adulthood and in the neonatal period.", "content": "Effects of sex hormones on sleep patterns of male rats gonadectomized in adulthood and in the neonatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355941"}
{"pmid": "4355944", "title": "Pituitary-adrenocortical activity and intermale aggressiveness in isolated mice.", "content": "Pituitary-adrenocortical activity and intermale aggressiveness in isolated mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355944"}
{"pmid": "4355946", "title": "Contrast filling of the lymphatic system of the lung through a pulmonary vein in the dog.", "content": "Contrast filling of the lymphatic system of the lung through a pulmonary vein in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355946"}
{"pmid": "4355945", "title": "Insulitis in cytomegalovirus infection in a newborn infant.", "content": "Insulitis in cytomegalovirus infection in a newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355945"}
{"pmid": "4355947", "title": "Effect of alcohol on albumin synthesis by the isolated perfused rat liver.", "content": "Effect of alcohol on albumin synthesis by the isolated perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355947"}
{"pmid": "4355948", "title": "Delayed radiation necrosis of the optic nerve.", "content": "Delayed radiation necrosis of the optic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355948"}
{"pmid": "4355950", "title": "Roentgenologic demonstration of spontaneous reversal of portal blood flow in cirrhosis and primary carcinoma of the liver.", "content": "Roentgenologic demonstration of spontaneous reversal of portal blood flow in cirrhosis and primary carcinoma of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355950"}
{"pmid": "4355949", "title": "Adult cytomegalic inclusion retinitis.", "content": "Adult cytomegalic inclusion retinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355949"}
{"pmid": "4355951", "title": "A quantitative serologic assay for diagnosing congenital infections of cattle.", "content": "A quantitative serologic assay for diagnosing congenital infections of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355951"}
{"pmid": "4355952", "title": "Passive immunity in the foal: measurement of immunoglobulin classes and specific antibody.", "content": "Passive immunity in the foal: measurement of immunoglobulin classes and specific antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355952"}
{"pmid": "4355954", "title": "Clinical conference: Essential hypertension: new concepts about mechanisms.", "content": "Clinical conference: Essential hypertension: new concepts about mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355954"}
{"pmid": "4355955", "title": "Letter: Cytomegalovirus mononucleosis with severe thrombocytopenia.", "content": "Letter: Cytomegalovirus mononucleosis with severe thrombocytopenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355955"}
{"pmid": "4355953", "title": "Calcium pyrophosphate dihydrate crystal deposition in neuropathic joints. Four cases of polyarticular involvement.", "content": "Calcium pyrophosphate dihydrate crystal deposition in neuropathic joints. Four cases of polyarticular involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355953"}
{"pmid": "4355957", "title": "Conversion of hydrocortisone to estrogen in carcinoma of the breast after oophorectomy and adrenalectomy.", "content": "Conversion of hydrocortisone to estrogen in carcinoma of the breast after oophorectomy and adrenalectomy. This case report concerns a 52-year-old woman who underwent radical mastectomy.  Microscopic study revealed the tumor to be infiltrating ductal carcinoma.  Axillary lymph nodes contained metastatic tumor.  About a year later tumor recurrence was demonstrated in the lumbar vertebrae.  The disease progressed under local irradiation.  After another year bilateral oophorectomy and adrenalectomy were performed.  The patient died about 17 months after the last surgery with widespread metastatic disease.  This study was conducted with the patient on hydrocortisone replacement therapy beginning about 1 month after removal of the ovaries and adrenal glands.  5 microcuries of 4-14C-hydrocortisone were administered and 3 successive 24-hour urine specimens were collected and kept frozen.  The steroid conjugates were extracted from the urine, hydrolyzed, and the free steroids removed by solvent extraction.  The estrogen fraction from the urine was separated by sodium hydroxide extraction and purified by counter-current distribution, then analyzed.  It was found that the administered 4-14C-hydrocortisone was converted to 11 beta-hydroxyestradiol which possesses estrogenic activity.  The identified conversion product represented 5% of the radioactivity of all the extracts and .7% of the total administered radioactivity.  Other metabolic products of hydrocortisone isolated included cortol, urocortisol, and cortolone.  The site of conversion and the mechanisms involved require further study.  Such conversion to estrogens of circulating hormone used in adrenal replacement therapy could affect the mammary malignancies of these patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355957"}
{"pmid": "4355959", "title": "Breast xeroradiography: an analysis of our first 17 months.", "content": "Breast xeroradiography: an analysis of our first 17 months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355959"}
{"pmid": "4355960", "title": "Substrate specificity of mammalian D-glucuronolactone dehydrogenase.", "content": "Substrate specificity of mammalian D-glucuronolactone dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355960"}
{"pmid": "4355961", "title": "A serological study of bovine foetal immunoglobulins.", "content": "A serological study of bovine foetal immunoglobulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355961"}
{"pmid": "4355958", "title": "Role of hepatic bile composition in gallstone formation in baboons.", "content": "Role of hepatic bile composition in gallstone formation in baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355958"}
{"pmid": "4355966", "title": "Radiation-induced pair-wise radical formation in single crystals of thymine.", "content": "Radiation-induced pair-wise radical formation in single crystals of thymine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355966"}
{"pmid": "4355967", "title": "Structural studies of avian myeloblastosis virus: presence of transfer RNA in core component.", "content": "Structural studies of avian myeloblastosis virus: presence of transfer RNA in core component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355967"}
{"pmid": "4355968", "title": "Partial purification of a cyclic AMP phosphodiesterase from soybean callus. Isolation of a non-dialysable inhibitor.", "content": "Partial purification of a cyclic AMP phosphodiesterase from soybean callus. Isolation of a non-dialysable inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355968"}
{"pmid": "4355970", "title": "The effects of insulin, serum and glucose on total assayable activity and on soluble, debris-bound and latent activity of the hexokinase of normal- and polyoma virus-transformed BHK 21 cells.", "content": "The effects of insulin, serum and glucose on total assayable activity and on soluble, debris-bound and latent activity of the hexokinase of normal- and polyoma virus-transformed BHK 21 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355970"}
{"pmid": "4355962", "title": "Coccidiosis in chickens: obligate relationship between Eimeria tenella and certain species of cecal microflora in the pathogenesis of the disease.", "content": "Coccidiosis in chickens: obligate relationship between Eimeria tenella and certain species of cecal microflora in the pathogenesis of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355962"}
{"pmid": "4355971", "title": "Long-term aftercare for patients treated for thyrotoxicosis.", "content": "Long-term aftercare for patients treated for thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355971"}
{"pmid": "4355969", "title": "Metabolic enzymes in liver and kidney of the germfree rat.", "content": "Metabolic enzymes in liver and kidney of the germfree rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355969"}
{"pmid": "4355972", "title": "Electron microscope study of antigens in cells of mouse mammary tumor cell lines by peroxidase-labeled antibodies in sera of mammary tumor-bearing mice and of patients with breast cancer.", "content": "Electron microscope study of antigens in cells of mouse mammary tumor cell lines by peroxidase-labeled antibodies in sera of mammary tumor-bearing mice and of patients with breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355972"}
{"pmid": "4355973", "title": "Paramagnetic changes during development of a transplanted AKR-J leukemia in mice as measured by electron spin resonance.", "content": "Paramagnetic changes during development of a transplanted AKR-J leukemia in mice as measured by electron spin resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355973"}
{"pmid": "4355963", "title": "An experimental study of the pathogenesis of fowlpox infection in chickens.", "content": "An experimental study of the pathogenesis of fowlpox infection in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355963"}
{"pmid": "4355975", "title": "Quantitative estimations of RNA sensitive to mild RNase treatment in sections of normal, regenerating, and neoplastic rat livers.", "content": "Quantitative estimations of RNA sensitive to mild RNase treatment in sections of normal, regenerating, and neoplastic rat livers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355975"}
{"pmid": "4355974", "title": "Seroepidemiological studies on carcinoma of the nasopharynx.", "content": "Seroepidemiological studies on carcinoma of the nasopharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355974"}
{"pmid": "4355976", "title": "Effects of dimethylbenz(a)anthracene and dihydrotestosterone on estradiol-17 beta binding in rat mammary cytosol fraction.", "content": "Effects of dimethylbenz(a)anthracene and dihydrotestosterone on estradiol-17 beta binding in rat mammary cytosol fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355976"}
{"pmid": "4355977", "title": "Specific glucocorticoid binding in human hemopoietic cell lines and neoplastic tissue.", "content": "Specific glucocorticoid binding in human hemopoietic cell lines and neoplastic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355977"}
{"pmid": "4355978", "title": "Absence of aminonucleoside-sensitive steps in the cell cycle of SV40-transformed human fibroblasts.", "content": "Absence of aminonucleoside-sensitive steps in the cell cycle of SV40-transformed human fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355978"}
{"pmid": "4355979", "title": "Some properties of adenyl cyclase from Ehrlich tumor cells.", "content": "Some properties of adenyl cyclase from Ehrlich tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355979"}
{"pmid": "4355964", "title": "Immunization of chickens with an inactivated oil-adjuvant Newcastle disease virus vaccine.", "content": "Immunization of chickens with an inactivated oil-adjuvant Newcastle disease virus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355964"}
{"pmid": "4355980", "title": "The content of the principal protein target of a hepatic carcinogen in liver tumors.", "content": "The content of the principal protein target of a hepatic carcinogen in liver tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355980"}
{"pmid": "4355981", "title": "Two-dimensional gel electrophoresis of acid-soluble nucleolar proteins of Walker 256 carcinosarcoma, regenerating liver, and thioacetamide-treated liver.", "content": "Two-dimensional gel electrophoresis of acid-soluble nucleolar proteins of Walker 256 carcinosarcoma, regenerating liver, and thioacetamide-treated liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355981"}
{"pmid": "4355982", "title": "Methylhydrazine tumorigenesis in Syrian golden hamsters and the morphology of malignant histiocytomas.", "content": "Methylhydrazine tumorigenesis in Syrian golden hamsters and the morphology of malignant histiocytomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355982"}
{"pmid": "4355983", "title": "Specific estrogen binding in vivo in the R3230AC mammary adenocarcinoma of the rat.", "content": "Specific estrogen binding in vivo in the R3230AC mammary adenocarcinoma of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355983"}
{"pmid": "4355984", "title": "Insulin reversal of growth inhibition of plasma cell tumor by prostaglandin or adenosine 3',5'-monophosphate.", "content": "Insulin reversal of growth inhibition of plasma cell tumor by prostaglandin or adenosine 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355984"}
{"pmid": "4355985", "title": "Increased sialic acid density in surface glycoprotein of transformed and malignant cells--a general phenomenon?", "content": "Increased sialic acid density in surface glycoprotein of transformed and malignant cells--a general phenomenon?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355985"}
{"pmid": "4355965", "title": "Research note--avian encephalitis virus as a chicken kidney cell-culture contaminant and its effect on the growth of infectious bronchitis virus.", "content": "Research note--avian encephalitis virus as a chicken kidney cell-culture contaminant and its effect on the growth of infectious bronchitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355965"}
{"pmid": "4355986", "title": "Catabolism of nuclear proteins in control and phytohemagglutinin-stimulated human lymphocytes, leukemic leukocytes, and Burkitt lymphoma cells.", "content": "Catabolism of nuclear proteins in control and phytohemagglutinin-stimulated human lymphocytes, leukemic leukocytes, and Burkitt lymphoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355986"}
{"pmid": "4355987", "title": "Spectrophotometric analysis of cytochromes in Morris hepatomas.", "content": "Spectrophotometric analysis of cytochromes in Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355987"}
{"pmid": "4355988", "title": "Combined enzyme histochemical and radioautographic studies on areas of hyperplasia in the liver of rats fed N-2-fluorenylacetamide.", "content": "Combined enzyme histochemical and radioautographic studies on areas of hyperplasia in the liver of rats fed N-2-fluorenylacetamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355988"}
{"pmid": "4355989", "title": "Effects of riboflavin deficiency upon concentrations of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in Novikoff hepatoma in rats.", "content": "Effects of riboflavin deficiency upon concentrations of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in Novikoff hepatoma in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355989"}
{"pmid": "4355990", "title": "Effects of formamidoxime on macromolecular synthesis in regenerating liver and hepatomas.", "content": "Effects of formamidoxime on macromolecular synthesis in regenerating liver and hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355990"}
{"pmid": "4355991", "title": "The effect of silica dust on the phospholipid metabolism of macrophages.", "content": "The effect of silica dust on the phospholipid metabolism of macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355991"}
{"pmid": "4355992", "title": "Estimation of inorganic pyrophosphate phosphohydrolytic activity in human blood serum. The effects of serum constituents, magnesium and calcium.", "content": "Estimation of inorganic pyrophosphate phosphohydrolytic activity in human blood serum. The effects of serum constituents, magnesium and calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355992"}
{"pmid": "4355993", "title": "17(OH) corticosteroid and estrogen excretion with virilizing adrenal tumors.", "content": "17(OH) corticosteroid and estrogen excretion with virilizing adrenal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355993"}
{"pmid": "4355994", "title": "Interaction of various stimulators and inhibitors on insulin secretion in vitro.", "content": "Interaction of various stimulators and inhibitors on insulin secretion in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355994"}
{"pmid": "4355995", "title": "Electric stimulation of the olfactory mucosa: a new test for the study of the hypothalamic functionality.", "content": "Electric stimulation of the olfactory mucosa: a new test for the study of the hypothalamic functionality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355995"}
{"pmid": "4355996", "title": "A mechanism for stress-susceptibility in swine.", "content": "A mechanism for stress-susceptibility in swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355996"}
{"pmid": "4355997", "title": "A study of angiotensin II pressor response throughout primigravid pregnancy.", "content": "A study of angiotensin II pressor response throughout primigravid pregnancy. The present study was designed to ascertain sequentially the pressor response to angiotensin II in young primigravid patients throughout pregnancy in order a) to define when in pregnancy resistance to the pressor effects of angiotensin II develops; b) to define the physiologic sequence of events leading to this resistance; and c) to ascertain whether sensitivity to infused angiotensin II could be detected before the onset of clinical signs of pregnancy-induced hypertension. With this prospective approach, two separate groups of patients were defined. The first group of patients remained normal throughout pregnancy. The second group consisted of those patients who, while clinically normotensive during the initial phase of the study, ultimately developed hypertension of pregnancy.192 patients were studied; of these, 120 patients remained normotensive and 72 developed pregnancy-induced hypertension. In both groups, vascular resistance to infused angiotensin II (more than 8 ng/kg/min required to elicit a pressor response of 20 mm Hg in diastolic pressure) was demonstrated as early as the 10th wk of pregnancy. In the group that remained normotensive, maximum mean vascular resistance occurred at 18-30 wk of pregnancy, (mean pressor dose required being 13.5 to 14.9 ng/kg/min). In those subjects who developed pregnancy-induced hypertension, the mean maximum dose required was 12.9 ng/kg/min, which was observed at the 18th wk of pregnancy. By the 22nd wk there was a clear separation of the two groups, with the mean dose requirement of the subjects destined to develop hypertension being progressively less than that of those who remained normal. The difference between the two groups became significant (P < 0.01) by 23-26 wk of pregnancy. Among patients requiring more than 8 ng/kg/min on one or more tests done between wk 28-32, 91% remained normotensive. Conversely, during the same time period among patients requiring less than 8 ng/kg/min, on at least one occasion, 90% developed pregnancy-induced hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355997"}
{"pmid": "4355998", "title": "Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria.", "content": "Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. Endothelial cells were isolated from freshly obtained human umbilical cords by collagenase digestion of the interior of the umbilical vein. The cells were grown in tissue culture as a homogeneous population for periods up to 5 mo and some lines were subcultured for 10 serial passages. During the logarithmic phase of cell growth, cell-doubling time was 92 h. Light, phase contrast, and scanning electron microscopy demonstrated that cultured human endothelial cells grew as monolayers of closely opposed, polygonal large cells whereas both cultured human fibroblasts and human smooth muscle cells grew as overlapping layers of parallel arrays of slender, spindle-shaped cells. By transmission electron microscopy, cultured endothelial cells were seen to contain cytoplasmic inclusions (Weibel-Palade bodies) characteristic of in situ endothelial cells. These inclusions were also found in endothelial cells lining umbilical veins but were not seen in smooth muscle cells or fibroblasts in culture or in situ. Cultured endothelial cells contained abundant quantities of smooth muscle actomyosin. Cultured endothelial cells also contained ABH antigens appropriate to the tissue donor's blood type; these antigens were not detectable on cultured smooth muscle cells or fibroblasts. These studies demonstrate that it is possible to culture morphologically and immunologically identifiable human endothelial cells for periods up to 5 mo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355998"}
{"pmid": "4355999", "title": "The metabolism of cholestanol, cholesterol, and bile acids in cerebrotendinous xanthomatosis.", "content": "The metabolism of cholestanol, cholesterol, and bile acids in cerebrotendinous xanthomatosis. The metabolism of cholesterol and its 5-dihydro derivative, cholestanol, was investigated by means of sterol balance and isotope kinetic techniques in 3 subjects with cerebrotendinous xanthomatosis (CTX) and 11 other individuals. All subjects were hospitalized on a metabolic ward and were fed diets practically free of cholesterol and cholestanol. After the intravenous administration of [1,2-(3)H]cholestanol, the radioactive sterol was transported and esterified in plasma lipoproteins in an identical manner to cholesterol. In these short-term experiments, the specific activity-time curves of plasma cholestanol conformed to two-pool models in both the CTX and control groups. However, cholestanol plasma concentrations, total body miscible pools, and daily synthesis rates were two to five times greater in the CTX than control individuals. The short-term specific activity decay curves of plasma [4-(14)C]cholesterol also conformed to two-pool models in both groups. However, in the CTX subjects the decay was more rapid, and daily cholesterol synthesis was nearly double that of the control subjects. Plasma concentrations and the sizes of the rapidly turning over pool of exchangeable cholesterol were apparently small in the CTX subjects, and these measurements did not correlate with the large cholesterol deposits found in tendon and tuberous xanthomas. Despite active cholesterol synthesis, bile acid formation was subnormal in the CTX subjects. However, bile acid sequestration was accompanied by a rise in plasma cholestanol levels and greatly augmented fecal cholestanol outputs. In contrast, the administration of clofibrate lowered plasma cholesterol levels 50% and presumably reduced synthesis in the CTX subjects. Plasma cholesterol concentrations and fecal steroid excretion did not change significantly during this therapy. These findings indicate that the excessive tissue deposits of cholesterol and cholestanol that characterize CTX were associated with hyperactive neutral sterol synthesis. The demonstration of subnormal bile acid formation suggests that defective bile acid synthesis may predispose to the neutral sterol abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4355999"}
{"pmid": "4356001", "title": "Immune enhancement of pulmonary bactericidal activity in murine virus pneumonia.", "content": "Immune enhancement of pulmonary bactericidal activity in murine virus pneumonia. Bacterial multiplication in the lung associated with murine Sendai virus pneumonia is caused by virus-induced defects in pulmonary bactericidal mechanisms. The nature of this effect has been studied in animals immunized against the challenge bacteria. Mice were immunized against Proteus mirabilis by intraperitoneal inoculation and by aerosol inhalation. After the development of immunity, mice were infected aerogenically with 10(4) TCID(50) of Sendai virus. 7 days later, during the height of the bronchial inflammation and pulmonary consolidation, the mice were challenged with an aerosol of viable (35)S-labeled Proteus mirabilis or (32)P-labeled Staphylococcus aureus.Nonimmunized virus-infected animals showed marked impairment of pulmonary bactericidal activity with subsequent multiplication of the bacterial strain in the case of Proteus mirabilis. Immunized nonvirus-infected animals showed enhancement of pulmonary bactericidal activity for the homologous and heterologous strains in comparison with nonimmunized animals. Virus-infected animals immunized by aerosol showed enhanced bactericidal activity against the homologous but not the heterologous bacterial strain. Neither virus infection nor immunization had a significant effect on the transport of particles in the lung. The data demonstrated that the bacterial multiplication associated with the virus pneumonia was prevented by preceding immunization against the homologous challenge organism. The data suggest a mechanism for controlling bacterial multiplication associated with virus pneumonias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356001"}
{"pmid": "4356000", "title": "In vivo suppression of the immune response to alloantigen by cholera enterotoxin.", "content": "In vivo suppression of the immune response to alloantigen by cholera enterotoxin. The immune response of C57BL/6 mice to allogeneic (DBA/2) mastocytoma cell suspensions was profoundly suppressed by intraperitoneal administration of 1 mug cholera enterotoxin 4 days after antigenic stimulation. The immune response assayed 11 days after antigen showed decreased cytolytically active thymusderived (T) lymphocytes and markedly depressed serumagglutinating titers. A comparable suppression of the immune response to skin allografts (DBA/2-->C57BL/6) was also effected by cholera toxin administration, although there was no prolongation of allograft survival. The mechanism of the immune suppression is apparently related to the known adenylate cyclase stimulatory activities of choleragen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356000"}
{"pmid": "4356002", "title": "Lymph chylomicron formation during the inhibition of protein synthesis. Studies of chylomicron apoproteins.", "content": "Lymph chylomicron formation during the inhibition of protein synthesis. Studies of chylomicron apoproteins. The effect of impaired intestinal protein synthesis on chylomicron apoprotein composition was studied in mesenteric lymph fistula rats. Lymph was obtained from animals with impaired protein synthesis given intraperitoneal acetoxycycloheximide (ACH), a potent inhibitor of protein synthesis. Lymph chylomicrons were then isolated by ultracentrifugation and purified on agarose columns. Purified chylomicrons from control and ACH-treated animals were delipidated, and their apoprotein pattern was examined on sodium dodecyl sulfate (SDS) polyacrylamide gels. Because we had previously demonstrated a markedly increased lymph chylomicron size during the inhibition of protein synthesis, it was first necessary to determine whether chylomicron apoprotein composition normally varied with chylomicron size. Chylomicrons of varying sizes were prepared by differential ultracentrifugation, and their apoprotein composition was determined densitometrically on SDS polyacrylamide gels. No significant difference in apoprotein composition was found normally with varying chylomicron size. In contrast, however, chylomicrons from ACH-treated animals showed a 50% decrease in a major apoprotein band with R(1) 0.67. Other chylomicron apoproteins were not decreased as a result of impaired protein synthesis, suggesting differing rates of synthesis of the various chylomicron apoproteins. In vivo incorporation studies of [(3)H]leucine into the various apoproteins of lymph chylomicrons demonstrated that this apoprotein (R(1) 0.67) had the most rapid synthesis rate and suggested that it seemed most affected by impaired intestinal protein synthesis. Immunologic studies indicated that this apoprotein was immunologically related to high-density lipoproteins (HDL) and was present in chylomicrons isolated directly from small intestinal mucosa. These studies demonstrate that impaired intestimal protein synthesis is associated with a deficiency in one of the major chylomicron apoproteins and may in part explain the impaired lipid absorption seen during states of impaired protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356002"}
{"pmid": "4356003", "title": "Alkaline phosphatase. Possible induction by cyclic AMP after cholera enterotoxin administration.", "content": "Alkaline phosphatase. Possible induction by cyclic AMP after cholera enterotoxin administration. The present studies were undertaken to determine the role, if any, of cyclic 3',5'-adenosine monophosphate (cyclic AMP) as a chemical inducer of rat liver alkaline phosphatase. Cholera enterotoxin, given intravenously to rats, led to a rapid rise in the activity of hepatic adenyl cyclase that was 7(1/2) times greater than control values in 6 h. Cyclic AMP levels were also significantly increased above control values while the activity of cyclic nucleotide phosphodiesterase was unchanged. Hepatic alkaline phosphatase activity was increased 5(1/2) times above control in 12 h, but its rise followed that of adenyl cyclase and cyclic AMP by several hours. Cycloheximide inhibited the rise of hepatic alkaline phosphatase but not that of adenyl cyclase. The administration of glucagon, a known stimulator of hepatic adenyl cyclase, and of dibutyryl cyclic AMP, led to similar striking increases in hepatic alkaline phosphatase activity. This alkaline phosphatase increase was blocked by the prior administration of cycloheximide. Bile duct ligation, a known stimulator of hepatic alkaline phosphatase activity, failed to produce any significant changes in adenyl cyclase or cyclic AMP. Concomitant treatment of rats with bile duct ligation and cholera enterotoxin or bile duct ligation and glucagon, had no additive effect on the increase in hepatic alkaline phosphatase activity, although the increase occurred earlier. These results suggest that: (a) cyclic AMP may act as an inducer of hepatic alkaline phosphatase: (b) the stimulation of hepatic alkaline phosphatase by cholera enterotoxin is mediated by cyclic AMP; (c) the rise in hepatic alkaline phosphatase following bile duct ligation is not mediated by cyclic AMP; (d) the same alkaline phosphatase in rat liver may be induced by two (or more) mechanisms, only one of which requires cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356003"}
{"pmid": "4356005", "title": "A study of the androgen receptors in a variety of androgen-sensitive tissues.", "content": "A study of the androgen receptors in a variety of androgen-sensitive tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356005"}
{"pmid": "4356006", "title": "Corticosterone metabolism by rat adrenocortical cell suspensions and monolayer cultures: the effect of damage on 11-dehydrogenase activity.", "content": "Corticosterone metabolism by rat adrenocortical cell suspensions and monolayer cultures: the effect of damage on 11-dehydrogenase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356006"}
{"pmid": "4356008", "title": "Properties of a simplified bioassay for adrenocorticotrophic activity using the steroidogenic response of isolated adrenal cells.", "content": "Properties of a simplified bioassay for adrenocorticotrophic activity using the steroidogenic response of isolated adrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356008"}
{"pmid": "4356004", "title": "Prevention of gram-negative bacillary pneumonia using aerosol polymyxin as prophylaxis. I. Effect on the colonization pattern of the upper respiratory tract of seriously ill patients.", "content": "Prevention of gram-negative bacillary pneumonia using aerosol polymyxin as prophylaxis. I. Effect on the colonization pattern of the upper respiratory tract of seriously ill patients. A prospective study used polymyxin B by aerosol to reduce colonization of the upper respiratory tract with nosocomial gram-negative bacilli. 58 high-risk patients from the Respiratory-Surgical Intensive Care Unit entered the trial. 33 were randomly selected to receive 2.5 mg/kg/day of polymyxin B by hand atomizer into the pharynx, and tracheal tube if present. 17 of 25 control patients became colonized with gram-negative bacilli as compared with 7 of 33 polymyxin-treated patients (p < 0.01). Control patients became colonized with a total of 33 gram-negative bacilli: 3 were Pseudomonas aeruginosa, 21 were species of Enterobacteriaceae. The polymyxin-treated patients became colonized with a total of 11 gram-negative bacilli: no P. aeruginosa and only 3 species of Enterobacteriaceae were recovered. Colonization increased with duration in Respiratory-Surgical Intensive Care Unit and with time of required controlled ventilation. Polymyxin most effectively prevented the increase in colonization in treated patients who stayed in the Respiratory-Surgical Intensive Care Unit for longer than 1 wk and who required controlled ventilation for at least 72 h.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356004"}
{"pmid": "4356009", "title": "Some properties of the hydro-osmotic vasopressin \"effector\": interactions with N-ethylmaleimide.", "content": "Some properties of the hydro-osmotic vasopressin \"effector\": interactions with N-ethylmaleimide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356009"}
{"pmid": "4356007", "title": "The episodic nature of changes in ovine plasma cortisol levels and their response to adrenaline during adaptation to a new environment.", "content": "The episodic nature of changes in ovine plasma cortisol levels and their response to adrenaline during adaptation to a new environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356007"}
{"pmid": "4356010", "title": "Health services on economic development projects.", "content": "Health services on economic development projects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356010"}
{"pmid": "4356011", "title": "Paradoxical blockade by p-chlorophenylalanine of 5-hydroxytryptophan facilitatory actions on spinal reflexes.", "content": "Paradoxical blockade by p-chlorophenylalanine of 5-hydroxytryptophan facilitatory actions on spinal reflexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356011"}
{"pmid": "4356012", "title": "Effects of phenoperidine on lamina V cells in the cat dorsal horn.", "content": "Effects of phenoperidine on lamina V cells in the cat dorsal horn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356012"}
{"pmid": "4356013", "title": "Changes in spinal cord neural mechanisms associated with digitalis administration.", "content": "Changes in spinal cord neural mechanisms associated with digitalis administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356013"}
{"pmid": "4356014", "title": "Antiarrhythmic and electrophysiologic properties of UM-272, dimethyl quaternary propranolol, in the canine heart.", "content": "Antiarrhythmic and electrophysiologic properties of UM-272, dimethyl quaternary propranolol, in the canine heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356014"}
{"pmid": "4356015", "title": "Phenylephrine-induced increases in cardiac contractility, cyclic adenosine monophosphate and phosphorylase a.", "content": "Phenylephrine-induced increases in cardiac contractility, cyclic adenosine monophosphate and phosphorylase a.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356015"}
{"pmid": "4356016", "title": "Effects of hycanthone on spermatogonial cells, deoxyribonucleic acid synthesis in bone marrow and dominant lethality in rats.", "content": "Effects of hycanthone on spermatogonial cells, deoxyribonucleic acid synthesis in bone marrow and dominant lethality in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356016"}
{"pmid": "4356017", "title": "Mutagenic action of hycanthone and IA-4 on yeast.", "content": "Mutagenic action of hycanthone and IA-4 on yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356017"}
{"pmid": "4356018", "title": "Fine structure of rat uterine eosinophils and the possible role of eosinophils in the mechanism of estrogen action.", "content": "Fine structure of rat uterine eosinophils and the possible role of eosinophils in the mechanism of estrogen action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356018"}
{"pmid": "4356019", "title": "Subcellular distribution and binding of (6,7-3H) estradiol in rat uterus, at equilibrium, after long-term intravenous infusion.", "content": "Subcellular distribution and binding of (6,7-3H) estradiol in rat uterus, at equilibrium, after long-term intravenous infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356019"}
{"pmid": "4356020", "title": "Dynamic exchange of (6, 73H) estradiol-17beta at the subcellular level in rat uterus.", "content": "Dynamic exchange of (6, 73H) estradiol-17beta at the subcellular level in rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356020"}
{"pmid": "4356021", "title": "Slowly exchangeable pool of estradiol in the rat uterus.", "content": "Slowly exchangeable pool of estradiol in the rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356021"}
{"pmid": "4356022", "title": "Evaluation of micropore filter in the extracorporeal circulation.", "content": "Evaluation of micropore filter in the extracorporeal circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356022"}
{"pmid": "4356025", "title": "Pulmonary phospholipids and surface properties of alveolar wash in experimental paraquat poisoning.", "content": "Pulmonary phospholipids and surface properties of alveolar wash in experimental paraquat poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356025"}
{"pmid": "4356026", "title": "Late effects of moderate doses of quartz dust on pulmonary function and tissue. An experimental study on rabbits.", "content": "Late effects of moderate doses of quartz dust on pulmonary function and tissue. An experimental study on rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356026"}
{"pmid": "4356028", "title": "Hepatitis A: detection by immune electron microscopy of a viruslike antigen associated with acute illness.", "content": "Hepatitis A: detection by immune electron microscopy of a viruslike antigen associated with acute illness. Spherical 27-nanometer particles were visualized in stools obtained from hepatitis A patients in the acute phase of the disease. The particle was serologically specific for this disease, and every hepatitis A patient tested demonstrated a serologic response to this antigen. The findings suggest that it is the etiologic agent of hepatitis A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356028"}
{"pmid": "4356027", "title": "Late effects of large doses of quartz dust on pulmonary function and tissue. An experimental study on rabbits.", "content": "Late effects of large doses of quartz dust on pulmonary function and tissue. An experimental study on rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356027"}
{"pmid": "4356029", "title": "Renin-angiotensin role in thirst: paradoxical enhancement of drinking by angiotensin converting enzyme inhibitor.", "content": "Renin-angiotensin role in thirst: paradoxical enhancement of drinking by angiotensin converting enzyme inhibitor. A competitive angiotensin converting enzyme antagonist SQ 20, 881 (SQ), was used to examine the role of the renin-angiotensin system in putative renin-dependent thirst in the albino rat. Significant enhancement of \"renin-dependent\" as well as renin-independent drinking was observed in the presence of peripheral SQ. Intraventricular SQ obviated this enhancement of drinking but did not affect the water intake caused by the original stimulus itself, whereas it sharply reduced drinking evoked by peripheral renin in nephrectomized rats. Prior renin depletion likewise had no influence on so-called renin-dependent thirst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356029"}
{"pmid": "4356030", "title": "Serological survey on infection with equine rhinopneumonitis virus among soliped animals in Iran.", "content": "Serological survey on infection with equine rhinopneumonitis virus among soliped animals in Iran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356030"}
{"pmid": "4356031", "title": "Ultrastructure of Leydig cell paracrystalline inclusions, possibly related to Reinke crystals, in the normal human testis.", "content": "Ultrastructure of Leydig cell paracrystalline inclusions, possibly related to Reinke crystals, in the normal human testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356031"}
{"pmid": "4356032", "title": "Ultrastructural investigation of the postnatal development of the hamster Harderian gland. II. Male and female.", "content": "Ultrastructural investigation of the postnatal development of the hamster Harderian gland. II. Male and female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356032"}
{"pmid": "4356033", "title": "Post-coital depletion of dense-core vesicles from the external layer of the rabbit median eminence.", "content": "Post-coital depletion of dense-core vesicles from the external layer of the rabbit median eminence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356033"}
{"pmid": "4356034", "title": "The structural organization of glomerular neuropile in the olfactory and accessory lobes of an Australian freshwater crayfish, Cherax destructor.", "content": "The structural organization of glomerular neuropile in the olfactory and accessory lobes of an Australian freshwater crayfish, Cherax destructor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356034"}
{"pmid": "4356035", "title": "On the regeneration of the eye in Helix aspersa and Cryptomphallus aspersa.", "content": "On the regeneration of the eye in Helix aspersa and Cryptomphallus aspersa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356035"}
{"pmid": "4356037", "title": "Fine structure of eyespots in tornarian larvae (phylum: Hemichordata).", "content": "Fine structure of eyespots in tornarian larvae (phylum: Hemichordata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356037"}
{"pmid": "4356039", "title": "Electron microscopic studies of human pituitary tumors. II. Acidophilic adenomas.", "content": "Electron microscopic studies of human pituitary tumors. II. Acidophilic adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356039"}
{"pmid": "4356038", "title": "Pinocytotic activity of the uterus of the rat.", "content": "Pinocytotic activity of the uterus of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356038"}
{"pmid": "4356040", "title": "Kinetics of viral adsorption in singly and multiply infected bovine cells.", "content": "Kinetics of viral adsorption in singly and multiply infected bovine cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356040"}
{"pmid": "4356036", "title": "Cholinesterase in the posterior and intermediate lobes of the pituitary. Species differences as determined by light and electron microscopic histochemistry.", "content": "Cholinesterase in the posterior and intermediate lobes of the pituitary. Species differences as determined by light and electron microscopic histochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356036"}
{"pmid": "4356041", "title": "Field experiments with formalin-killed-virus vaccine against infectious bovine rhinotracheitis, bovine viral diarrhea and parainfluenza-3.", "content": "Field experiments with formalin-killed-virus vaccine against infectious bovine rhinotracheitis, bovine viral diarrhea and parainfluenza-3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356041"}
{"pmid": "4356043", "title": "Distal and proximal sensory responses during stereotactic spinal tractotomy in man.", "content": "Distal and proximal sensory responses during stereotactic spinal tractotomy in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356043"}
{"pmid": "4356044", "title": "Foreign cell acantholysis. Electron microscopic study on the pathodynamics of exocytosis.", "content": "Foreign cell acantholysis. Electron microscopic study on the pathodynamics of exocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356044"}
{"pmid": "4356045", "title": "Ultrastructure of signet ring cells in cutaneous metastases of gastric carcinoma.", "content": "Ultrastructure of signet ring cells in cutaneous metastases of gastric carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356045"}
{"pmid": "4356046", "title": "Effects of local anesthetics on glucose-stimulated insulin secretion from rat pancreas in vitro.", "content": "Effects of local anesthetics on glucose-stimulated insulin secretion from rat pancreas in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356046"}
{"pmid": "4356047", "title": "Studies relating to the antihypertensive and antidysrhythmic action of indoramin.", "content": "Studies relating to the antihypertensive and antidysrhythmic action of indoramin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356047"}
{"pmid": "4356048", "title": "Nature of the transport ATPase-digitalis complex. VI. Purification of and ouabain binding to a highly active cardiac Na+, K+-ATPase.", "content": "Nature of the transport ATPase-digitalis complex. VI. Purification of and ouabain binding to a highly active cardiac Na+, K+-ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356048"}
{"pmid": "4356049", "title": "Two-dimensional polyacrylamide gel electrophoresis of chromatin proteins of normal rat liver and Novikoff hepatoma ascites cells.", "content": "Two-dimensional polyacrylamide gel electrophoresis of chromatin proteins of normal rat liver and Novikoff hepatoma ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356049"}
{"pmid": "4356051", "title": "Evidence for the presence of 3', 5'-cyclic AMP in plant tissues.", "content": "Evidence for the presence of 3', 5'-cyclic AMP in plant tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356051"}
{"pmid": "4356052", "title": "Proline biosynthesis: multiple defects in Chinese hamster ovary cells.", "content": "Proline biosynthesis: multiple defects in Chinese hamster ovary cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356052"}
{"pmid": "4356050", "title": "Isolation of tissue collagenase from homogenates of embryonic chick bones.", "content": "Isolation of tissue collagenase from homogenates of embryonic chick bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356050"}
{"pmid": "4356053", "title": "Effect of concanavalin A on cellular slime mold development: premature appearance of membrane-bound cyclic AMP phosphodiesterase.", "content": "Effect of concanavalin A on cellular slime mold development: premature appearance of membrane-bound cyclic AMP phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356053"}
{"pmid": "4356054", "title": "Vasoactive intestinal polypeptide and glucagon: stimulation of adenylate cyclase activity via distinct receptors in liver and fat cell membranes.", "content": "Vasoactive intestinal polypeptide and glucagon: stimulation of adenylate cyclase activity via distinct receptors in liver and fat cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356054"}
{"pmid": "4356055", "title": "Effect of concanavalin A on interferon induction by poly IC.", "content": "Effect of concanavalin A on interferon induction by poly IC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356055"}
{"pmid": "4356056", "title": "Analogs of adenosine 3',5'-cyclic phosphate. II. Synthesis and enzymatic activity of derivatives of 1,N6-ethenoadenosine 3',5'-cyclic phosphate.", "content": "Analogs of adenosine 3',5'-cyclic phosphate. II. Synthesis and enzymatic activity of derivatives of 1,N6-ethenoadenosine 3',5'-cyclic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356056"}
{"pmid": "4356057", "title": "Effects of protein-modifying reagents on an isoenzyme of potato apyrase.", "content": "Effects of protein-modifying reagents on an isoenzyme of potato apyrase. Treatment of an isoenzyme of potato apyrase of high adenosine triphosphatase/adenosine diphosphatase (ATPase/ADPase) ratio with iodine, N-acetylimidazole or tetranitromethane inactivates the ATPase activity of this enzyme faster than its ADPase activity. There was protection by substrates with the two last-named substances. This and the appearance of nitrotyrosine suggests the participation of tyrosyl residues in both enzymic activities of potato apyrase. The participation of thiol groups is excluded by the insensitivity of apyrase to p-chloromercuribenzoate. Also, 2-hydroxy-5-nitrobenzyl bromide or carboxymethylation produce the same rate of inactivation of ATPase and ADPase activities. Substrates protect both activities from inactivation. Hydrogen peroxide and photo-oxidation inactivate ATPase activity faster than ADPase activity. There is no protection by substrates. Analysis of pH effects on V(max.) and K(m) suggest different pK values for the amino acid residues at the ATP and ADP sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356057"}
{"pmid": "4356058", "title": "Direct measurement of proton binding to the active ternary complex of pig heart lactate dehydrogenase.", "content": "Direct measurement of proton binding to the active ternary complex of pig heart lactate dehydrogenase. With the use of a glass electrode it is shown that one proton is taken up from the solvent when o-nitrophenylpyruvate forms a ternary complex with lactate dehydrogenase and NADH at pH8 and before the complex has rearranged to give products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356058"}
{"pmid": "4356059", "title": "Lipids of Crithidia fasciculata. The occurrence and turnover of phosphoinositides.", "content": "Lipids of Crithidia fasciculata. The occurrence and turnover of phosphoinositides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356059"}
{"pmid": "4356060", "title": "The sphingolipid composition of bovine kidney cortex, medulla and papilla.", "content": "The sphingolipid composition of bovine kidney cortex, medulla and papilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356060"}
{"pmid": "4356061", "title": "Detailed structure of sphingomyelins and ceramides from different regions of bovine kidney with special reference to long-chain bases.", "content": "Detailed structure of sphingomyelins and ceramides from different regions of bovine kidney with special reference to long-chain bases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356061"}
{"pmid": "4356062", "title": "Microbiological optical resolution of a racemic synthetic prostaglandin intermediate.", "content": "Microbiological optical resolution of a racemic synthetic prostaglandin intermediate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356062"}
{"pmid": "4356063", "title": "Effects of antilipolytic agents and alpha-adrenergic antagonists on cyclic AMP metabolism in hamster white adipocytes.", "content": "Effects of antilipolytic agents and alpha-adrenergic antagonists on cyclic AMP metabolism in hamster white adipocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356063"}
{"pmid": "4356064", "title": "Sialography: past, present, and future.", "content": "Sialography: past, present, and future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356064"}
{"pmid": "4356065", "title": "Selective inhibition of human distal tubular function by demeclocycline.", "content": "Selective inhibition of human distal tubular function by demeclocycline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356065"}
{"pmid": "4356069", "title": "Anti-shock action of steroids other than cortisone.", "content": "Anti-shock action of steroids other than cortisone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356069"}
{"pmid": "4356070", "title": "Effect of biliary tract obstruction on liver microsomes in the rat.", "content": "Effect of biliary tract obstruction on liver microsomes in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356070"}
{"pmid": "4356072", "title": "Synergistic effect in viral-bacterial infection: combined infection of the murine respiratory tract with Sendai virus and Pasteurella pneumotropica.", "content": "Synergistic effect in viral-bacterial infection: combined infection of the murine respiratory tract with Sendai virus and Pasteurella pneumotropica. Synergism was demonstrated between Sendai virus and Pasteurella pneumotropica in the respiratory tract of mice showing no evidence of previous infection with either agent. Mice aerosol challenged with P. pneumotropica invariably eliminated the viable organism from their lungs within 72 h. In contrast, intrapulmonary killing was delayed in animals previously infected with Sendai virus. Maximum synergism was observed when virus infection preceded bacterial challenge by 6 days. At this time, a mortality rate of 37% was observed as compared with 0, 10, 20, and 10%, respectively, in those animals in which the virus infection preceded bacterial challenge by 1, 3, 9, and 12 days. Previous immunization with Sendai virus completely prevented virus infection and thus the synergistic effect. Synergism with endogenous flora was also noted. Six days after virus infection an endogenous Pasteurella sp. began to proliferate in the bronchopulmonary tissues. Up to 10(4) colony-forming units per lung were recovered but no animals died of the endogenous Pasteurella infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356072"}
{"pmid": "4356071", "title": "Role of immunity in viral-induced bacterial superinfections of the lung.", "content": "Role of immunity in viral-induced bacterial superinfections of the lung. Although viral illnesses are predisposing causes for pulmonary bacterial infections, the interrelationships of viral virulence and host immunity to alterations in susceptibility to bacterial infection are incompletely understood. We used two mutant strains of encephalomyocarditis virus (minimally virulent Mengo-37A and a highly virulent Columbia SK [Col-SK]) to investigate these interrelationships. Mice that had been immunized to Mengo-37A, and nonimmunized controls, were challenged with aerosols containing 10(4) plaque-forming units of Mengo-37A or Col-SK per liter. The effect of each viral infection on pulmonary antibacterial activity was assessed 3 days later by measuring the capacity of the lungs to kill inhaled radiophosphorus ((32)P)-labeled Staphylococcus aureus. The degree of antibacterial dysfunction found was proportional to the virulence of the infecting virus. If the host was immune to the infecting virus, bactericidal function was not impaired by viral challenge. Neither mutant caused significant pulmonary damage; therefore: (i) viral-induced impairment in bactericidal activity reflects, quantitatively, the virulence of the virus and (ii) viral immunity protects pulmonary bacterial defenses by preventing damage to the phagocyte from the virus or its attendant metabolic abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356071"}
{"pmid": "4356074", "title": "Functional development of the hypothalamo-hypophyseal-adrenal cortex axis in the chick embryo, Gallus domesticus.", "content": "Functional development of the hypothalamo-hypophyseal-adrenal cortex axis in the chick embryo, Gallus domesticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356074"}
{"pmid": "4356073", "title": "Mycoplasma-associated induction of interferon in ovine leukocytes.", "content": "Mycoplasma-associated induction of interferon in ovine leukocytes. A mycoplasmal species, Acholeplasma laidlawii, isolated as a contaminant from a fetal lamb kidney cell line, was shown to be associated with the induction of interferon in cultures of ovine peripheral blood leukocytes. Broth cultures of the mycoplasma induced between 20 and 230 U of interferon per ml in leukocytes from two adult ewes. The amount of interferon produced correlated with the inoculum size of mycoplasma. Interferon production was associated with replication of the mycoplasma in the leukocyte cultures. Interferon was not induced by sterile mycoplasmal broth, a cell-free filtrate of the mycoplasmal cultures, or heat-inactivated mycoplasmas. The antiviral substance was characterized as interferon by the usual criteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356073"}
{"pmid": "4356075", "title": "Ultrastructure of the intermediate stages in the reverting L-phase organisms of Staphylococcus aureus and Streptococcus faecalis.", "content": "Ultrastructure of the intermediate stages in the reverting L-phase organisms of Staphylococcus aureus and Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356075"}
{"pmid": "4356076", "title": "Studies on lysosomal acid phosphatase in virus infected HEp-2 cells.", "content": "Studies on lysosomal acid phosphatase in virus infected HEp-2 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356076"}
{"pmid": "4356077", "title": "In vitro uptake of active nerve growth factor by dorsal root ganglia of embryonic chick.", "content": "In vitro uptake of active nerve growth factor by dorsal root ganglia of embryonic chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356077"}
{"pmid": "4356078", "title": "Changes in myelin following trauma of the spinal cord in monkeys.", "content": "Changes in myelin following trauma of the spinal cord in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356078"}
{"pmid": "4356079", "title": "Elaidic acid and serum lipoproteins in starved and fed rats.", "content": "Elaidic acid and serum lipoproteins in starved and fed rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356079"}
{"pmid": "4356080", "title": "Phosphatase systems in Fasciolopsis buski Lankester, 1857 and Gastrodiscus aegyptiacus cobbold, 1876.", "content": "Phosphatase systems in Fasciolopsis buski Lankester, 1857 and Gastrodiscus aegyptiacus cobbold, 1876.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356080"}
{"pmid": "4356081", "title": "The effect of parathyroid hormone on rabbit renal cortex adenyl cyclase during development.", "content": "The effect of parathyroid hormone on rabbit renal cortex adenyl cyclase during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356081"}
{"pmid": "4356082", "title": "Vitamin D-dependency rickets in institutionalized, mentally retarded children on long term anticonvulsant therapy. II. The response to 25-hydroxycholecalciferol and to vitamin D2.", "content": "Vitamin D-dependency rickets in institutionalized, mentally retarded children on long term anticonvulsant therapy. II. The response to 25-hydroxycholecalciferol and to vitamin D2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356082"}
{"pmid": "4356083", "title": "Effects of angiotensin on the central nervous system.", "content": "Effects of angiotensin on the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356083"}
{"pmid": "4356086", "title": "Phospholipids of outer mitochondrial membranes. Effect of ascorbate on their polyunsaturated fatty acids.", "content": "Phospholipids of outer mitochondrial membranes. Effect of ascorbate on their polyunsaturated fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356086"}
{"pmid": "4356087", "title": "Endospores of actinomycetes: dormancy and germination.", "content": "Endospores of actinomycetes: dormancy and germination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356087"}
{"pmid": "4356089", "title": "Accelerated auto-infection with Strongyloides species complicating terminal carcinomatosis.", "content": "Accelerated auto-infection with Strongyloides species complicating terminal carcinomatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356089"}
{"pmid": "4356088", "title": "A parasitological survey in the Jogjakarta area of Central Java, Indonesia.", "content": "A parasitological survey in the Jogjakarta area of Central Java, Indonesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356088"}
{"pmid": "4356090", "title": "Sclerosing capillary hemangioma in a rhesus monkey.", "content": "Sclerosing capillary hemangioma in a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356090"}
{"pmid": "4356091", "title": "The metabolism of crotyl phosphate, crotyl alcohol and crotonaldehyde.", "content": "The metabolism of crotyl phosphate, crotyl alcohol and crotonaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356091"}
{"pmid": "4356094", "title": "Pseudotumour cerebri in Africans.", "content": "Pseudotumour cerebri in Africans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356094"}
{"pmid": "4356093", "title": "Carcinoid-islet cell tumors.", "content": "Carcinoid-islet cell tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356093"}
{"pmid": "4356097", "title": "Some aspects of ion movements across the membrane of mitochondria isolated from normal and tumour tissues.", "content": "Some aspects of ion movements across the membrane of mitochondria isolated from normal and tumour tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356097"}
{"pmid": "4356098", "title": "Insulin and ACTH production by a streptozotocin responsive islet cell carcinoma.", "content": "Insulin and ACTH production by a streptozotocin responsive islet cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356098"}
{"pmid": "4356099", "title": "Effects of streptozotocin on an islet cell carcinoma with hypercalcemia.", "content": "Effects of streptozotocin on an islet cell carcinoma with hypercalcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356099"}
{"pmid": "4356100", "title": "Endocrine studies in an arrhenoblastoma responsive to dexamethasone, ACTH and human chorionic gonadotropin.", "content": "Endocrine studies in an arrhenoblastoma responsive to dexamethasone, ACTH and human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356100"}
{"pmid": "4356101", "title": "Systemic lupus erythematosus with adrenal insufficiency.", "content": "Systemic lupus erythematosus with adrenal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356101"}
{"pmid": "4356103", "title": "One (of)alpha-1-lipoprotein in acute viral hepatitis.", "content": "One (of)alpha-1-lipoprotein in acute viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356103"}
{"pmid": "4356102", "title": "Bartter's syndrome and erythrocytosis.", "content": "Bartter's syndrome and erythrocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356102"}
{"pmid": "4356107", "title": "Study on pre-beta1 lipoprotein fraction.", "content": "Study on pre-beta1 lipoprotein fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356107"}
{"pmid": "4356109", "title": "The role of lecithin: cholesterol acyltransferase in the metabolism of plasma lipoproteins.", "content": "The role of lecithin: cholesterol acyltransferase in the metabolism of plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356109"}
{"pmid": "4356111", "title": "Prevalence of lipoprotein abnormalities in patients with peripheral vascular disease.", "content": "Prevalence of lipoprotein abnormalities in patients with peripheral vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356111"}
{"pmid": "4356117", "title": "Biochemical and clinical aspects of various lipoprotein patterns.", "content": "Biochemical and clinical aspects of various lipoprotein patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356117"}
{"pmid": "4356121", "title": "Aspartylglycosaminuria (AGU). Further aspects on its clinical picture, mode of inheritance and epidemiology based on a series of 57 patients.", "content": "Aspartylglycosaminuria (AGU). Further aspects on its clinical picture, mode of inheritance and epidemiology based on a series of 57 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356121"}
{"pmid": "4356122", "title": "Biochemical diagnosis of aspartylglycosaminuria.", "content": "Biochemical diagnosis of aspartylglycosaminuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356122"}
{"pmid": "4356123", "title": "Isolation of a murine hepatitis virus from Swiss mice treated with antilymphocyte serum.", "content": "Isolation of a murine hepatitis virus from Swiss mice treated with antilymphocyte serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356123"}
{"pmid": "4356124", "title": "The influence of mycoplasmas on the cytopathic effect of varicella virus.", "content": "The influence of mycoplasmas on the cytopathic effect of varicella virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356124"}
{"pmid": "4356126", "title": "Polyprenyl pyrophosphate-p-hydroxybenzoate polyprenyltransferase activity in mitochondria of broad-bean seeds and yeast.", "content": "Polyprenyl pyrophosphate-p-hydroxybenzoate polyprenyltransferase activity in mitochondria of broad-bean seeds and yeast. Cell-free homogenates prepared from broad-bean seeds and yeast cells are capable of synthesizing 4-carboxy-2-polyprenylphenols from p-hydroxybenzoate and either isopentenyl pyrophosphate or protein-bound polyprenyl pyrophosphates (produced by incubating a Micrococcus lysodeikticus extract with isopentenyl pyrophosphate). The mitochondria contained all the polyprenyl pyrophosphate-p-hydroxybenzoate polyprenyltransferase activity; however, unlike the homogenates they could not synthesize a side chain from isopentenyl pyrophosphate and had to be provided with protein-bound polyprenyl pyrophosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356126"}
{"pmid": "4356125", "title": "The electron-transport system of mitochondria from the slime mould Physarum polycephalum.", "content": "The electron-transport system of mitochondria from the slime mould Physarum polycephalum. A method is described for the preparation of mitochondria from the slime mould Physarum polycephalum; the mitochondria were not coupled. P. polycephalum mitochondria oxidized added NADH via a rotenone-insensitive pathway, but the oxidation of malate plus glutamate was rotenone sensitive; both of these substrates reduced much less cytochrome b than did succinate, in both aerobic and anaerobic steady states. Spectroscopy at 77 degrees K separated three absorption maxima in the alpha-band region, at 560nm, 553nm and one at 547nm due to cytochrome c. The absorption at 553nm was increased in the aerobic steady state by the addition of 2-heptyl-4-hydroxyquinoline N-oxide, suggesting that it was due to a b-type cytochrome. All three absorption maxima appeared in the aerobic steady state after the addition of a range of substrates. The respiratory activity with different substrates and the response to inhibitors of respiration were similar to those previously described for fungus mitochondria (Weiss et al., 1970; Erickson & Ashworth, 1969). When grown under conditions of haem limitation the mitochondria contained a lower concentration of cytochromes than normal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356125"}
{"pmid": "4356127", "title": "Hormone-sensitive adenylyl cyclases. Useful models for studying hormone receptor functions in cell-free systems.", "content": "Hormone-sensitive adenylyl cyclases. Useful models for studying hormone receptor functions in cell-free systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356127"}
{"pmid": "4356131", "title": "Alcohol inhibition of cyclic AMP-induced insulin release.", "content": "Alcohol inhibition of cyclic AMP-induced insulin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356131"}
{"pmid": "4356130", "title": "The detection of carcinoembryonic antigen in whole serum from patients with malignant and nonmalignant disease.", "content": "The detection of carcinoembryonic antigen in whole serum from patients with malignant and nonmalignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356130"}
{"pmid": "4356133", "title": "A post-training survey of community psychiatrists.", "content": "A post-training survey of community psychiatrists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356133"}
{"pmid": "4356134", "title": "Community liaison with a mental hospital.", "content": "Community liaison with a mental hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356134"}
{"pmid": "4356135", "title": "Growth hormone studies before and during catch-up growth in a child with emotional deprivation and short stature.", "content": "Growth hormone studies before and during catch-up growth in a child with emotional deprivation and short stature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356135"}
{"pmid": "4356136", "title": "Control of plasma aldosterone in primary aldosteronism: distinction between adenoma and hyperplasia.", "content": "Control of plasma aldosterone in primary aldosteronism: distinction between adenoma and hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356136"}
{"pmid": "4356137", "title": "Urinary cyclic 3',5'-adenosine monophosphate levels in diabetes mellitus before and after treatment.", "content": "Urinary cyclic 3',5'-adenosine monophosphate levels in diabetes mellitus before and after treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356137"}
{"pmid": "4356138", "title": "Synthesis and biological activity of certain carbamoyl and alkoxycarbonyl derivatives of adenosine 3',5'-cyclic phosphate.", "content": "Synthesis and biological activity of certain carbamoyl and alkoxycarbonyl derivatives of adenosine 3',5'-cyclic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356138"}
{"pmid": "4356139", "title": "Pancuronium bromide and other steroidal neuromuscular blocking agents containing acetylcholine fragments.", "content": "Pancuronium bromide and other steroidal neuromuscular blocking agents containing acetylcholine fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356139"}
{"pmid": "4356140", "title": "Solid-phase synthesis of (3-proline,8-isoleucine)-,(1-sarcosine,3-proline,8-isoleucine)-, and (4-phenylalanine,8-isoleucine)angiotensin II as the antagonists of the parent hormone.", "content": "Solid-phase synthesis of (3-proline,8-isoleucine)-,(1-sarcosine,3-proline,8-isoleucine)-, and (4-phenylalanine,8-isoleucine)angiotensin II as the antagonists of the parent hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356140"}
{"pmid": "4356141", "title": "Reconstitution of cytochrome oxidase vesicles and conferral of sensitivity to energy transfer inhibitors.", "content": "Reconstitution of cytochrome oxidase vesicles and conferral of sensitivity to energy transfer inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356141"}
{"pmid": "4356142", "title": "Intercellular communication and tissue growth. VI. Failure of exchange of endogeneous molecules between cancer cells with defective junctions and noncancerous cells.", "content": "Intercellular communication and tissue growth. VI. Failure of exchange of endogeneous molecules between cancer cells with defective junctions and noncancerous cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356142"}
{"pmid": "4356143", "title": "Molecular sieving of red cell membranes during gradual osmotic hemolysis.", "content": "Molecular sieving of red cell membranes during gradual osmotic hemolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356143"}
{"pmid": "4356144", "title": "Studies on the epidemiology, microbiology and immunology of trachoma among children at three centres in Western Australia.", "content": "Studies on the epidemiology, microbiology and immunology of trachoma among children at three centres in Western Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356144"}
{"pmid": "4356145", "title": "Familial combined hyperlipoproteinemia: studies in 91 adults and 95 children from 33 kindreds.", "content": "Familial combined hyperlipoproteinemia: studies in 91 adults and 95 children from 33 kindreds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356145"}
{"pmid": "4356146", "title": "Cortisol metabolism in glucose-6-phosphate dehydrogenase deficiency.", "content": "Cortisol metabolism in glucose-6-phosphate dehydrogenase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356146"}
{"pmid": "4356147", "title": "Etiology of progressive multifocal leukoencephalopathy. Identification of papovavirus.", "content": "Etiology of progressive multifocal leukoencephalopathy. Identification of papovavirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356147"}
{"pmid": "4356148", "title": "Herpes simplex meningitis: isolation of herpes simplex virus type 2 from cerebrospinal fluid.", "content": "Herpes simplex meningitis: isolation of herpes simplex virus type 2 from cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356148"}
{"pmid": "4356149", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 50-1973.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 50-1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356149"}
{"pmid": "4356150", "title": "Cyclic GMP and cell movement.", "content": "Cyclic GMP and cell movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356150"}
{"pmid": "4356151", "title": "Possible involvement of taurine in the genesis of muscular dystrophy.", "content": "Possible involvement of taurine in the genesis of muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356151"}
{"pmid": "4356152", "title": "Salting-out in amphiphilic gels as a new approach to hydrophobic adsorption.", "content": "Salting-out in amphiphilic gels as a new approach to hydrophobic adsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356152"}
{"pmid": "4356154", "title": "Depression of substrate inhibition in gamma irradiated lactic dehydrogenase.", "content": "Depression of substrate inhibition in gamma irradiated lactic dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356154"}
{"pmid": "4356153", "title": "The fluorescence of quinacrine mustard with nucleic acids.", "content": "The fluorescence of quinacrine mustard with nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356153"}
{"pmid": "4356155", "title": "Intake and excretion patterns of naturally occurring radium-226 in humans.", "content": "Intake and excretion patterns of naturally occurring radium-226 in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356155"}
{"pmid": "4356177", "title": "Proteolytic degradation of polymyxins by the enzymes of Bacillus polymyxa.", "content": "Proteolytic degradation of polymyxins by the enzymes of Bacillus polymyxa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356177"}
{"pmid": "4356180", "title": "Polarized single crystal absorption spectra of carboxy- and oxyhemoglobin.", "content": "Polarized single crystal absorption spectra of carboxy- and oxyhemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356180"}
{"pmid": "4356179", "title": "The chemistry of porphyrin pi-cations.", "content": "The chemistry of porphyrin pi-cations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356179"}
{"pmid": "4356181", "title": "The molecular structure of porphyrin complexes in solution: the interaction of metal porphyrins with various steroids.", "content": "The molecular structure of porphyrin complexes in solution: the interaction of metal porphyrins with various steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356181"}
{"pmid": "4356182", "title": "Electron paramagnetic resonance studies of iron porphin and chlorin systems.", "content": "Electron paramagnetic resonance studies of iron porphin and chlorin systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356182"}
{"pmid": "4356184", "title": "Metal-metal interactions involving porphyrins: iron-iron spin exchange and iron-chromium electron transfer.", "content": "Metal-metal interactions involving porphyrins: iron-iron spin exchange and iron-chromium electron transfer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356184"}
{"pmid": "4356183", "title": "ESR studies of porphyrin pi-cations: the 2A1u and 2A2u states.", "content": "ESR studies of porphyrin pi-cations: the 2A1u and 2A2u states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356183"}
{"pmid": "4356185", "title": "Oxidation of ferric porphyrins.", "content": "Oxidation of ferric porphyrins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356185"}
{"pmid": "4356187", "title": "The study of Zn porphin in an n-octane crystal by optical spectroscopy and magnetic resonance.", "content": "The study of Zn porphin in an n-octane crystal by optical spectroscopy and magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356187"}
{"pmid": "4356186", "title": "Chemistry of type c heme-peptide systems.", "content": "Chemistry of type c heme-peptide systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356186"}
{"pmid": "4356188", "title": "Proceedings: Linear and skeletal growth in congenital adrenal hyperplasia.", "content": "Proceedings: Linear and skeletal growth in congenital adrenal hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356188"}
{"pmid": "4356189", "title": "1,6-Di-O-methanesulphonyl-2,3-4,5-dianhydro-L-iditol, a new potential antitumour agent. Biological investigations.", "content": "1,6-Di-O-methanesulphonyl-2,3-4,5-dianhydro-L-iditol, a new potential antitumour agent. Biological investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356189"}
{"pmid": "4356194", "title": "The Cell.", "content": "The Cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356194"}
{"pmid": "4356195", "title": "Entamoeba histolytica.", "content": "Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356195"}
{"pmid": "4356196", "title": "The prevalence of entamoeba histolytica cyst-passers among hospital inpatients at Princess Tsehai Memorial Hospital.", "content": "The prevalence of entamoeba histolytica cyst-passers among hospital inpatients at Princess Tsehai Memorial Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356196"}
{"pmid": "4356197", "title": "Gas chromatographic determination of vitamin D in cod liver oil, pharmaceuticals and veterinary preparations.", "content": "Gas chromatographic determination of vitamin D in cod liver oil, pharmaceuticals and veterinary preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356197"}
{"pmid": "4356199", "title": "Aggregation of Hodgkin's disease.", "content": "Aggregation of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356199"}
{"pmid": "4356198", "title": "Inhibition of pyridoxal kinase from rat liver in vitro by aromatic and aliphatic amines.", "content": "Inhibition of pyridoxal kinase from rat liver in vitro by aromatic and aliphatic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356198"}
{"pmid": "4356200", "title": "Depression in the young.", "content": "Depression in the young.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356200"}
{"pmid": "4356201", "title": "Intraosseous malignant mixed tumor of the maxilla: review of the literature and report of case.", "content": "Intraosseous malignant mixed tumor of the maxilla: review of the literature and report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356201"}
{"pmid": "4356203", "title": "Increased production of cyclic AMP in gastric tissue by stimulation of histamine2 (H2)-receptors.", "content": "Increased production of cyclic AMP in gastric tissue by stimulation of histamine2 (H2)-receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356203"}
{"pmid": "4356204", "title": "Inhibitory effect of gammahydroxybutyric acid and gammaaminobutyric acid on the dopamine cells in the substantia nigra.", "content": "Inhibitory effect of gammahydroxybutyric acid and gammaaminobutyric acid on the dopamine cells in the substantia nigra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356204"}
{"pmid": "4356205", "title": "Release of prostaglandins from isolated cat spleen by angiotensin and vasopressin.", "content": "Release of prostaglandins from isolated cat spleen by angiotensin and vasopressin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356205"}
{"pmid": "4356208", "title": "Psychophysiology. Computer software.", "content": "Psychophysiology. Computer software.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356208"}
{"pmid": "4356207", "title": "Relationship of rapid eye movement density to the prior accumulation of sleep and wakefulness.", "content": "Relationship of rapid eye movement density to the prior accumulation of sleep and wakefulness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356207"}
{"pmid": "4356209", "title": "Failure of reserpinization to decrease the positive inotropic effect of dibutyryl cyclic AMP.", "content": "Failure of reserpinization to decrease the positive inotropic effect of dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356209"}
{"pmid": "4356210", "title": "Dibutyryl cyclic AMP--an effective antidote against lethal amounts of amobarbital in the rat.", "content": "Dibutyryl cyclic AMP--an effective antidote against lethal amounts of amobarbital in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356210"}
{"pmid": "4356212", "title": "Comparative studies on lipid composition of Zea mays L. and Typha latifolia L. pollens.", "content": "Comparative studies on lipid composition of Zea mays L. and Typha latifolia L. pollens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356212"}
{"pmid": "4356211", "title": "The effects of dibutyryl cyclic AMP on the hepatic mixed function oxidase system in hormonally altered rats.", "content": "The effects of dibutyryl cyclic AMP on the hepatic mixed function oxidase system in hormonally altered rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356211"}
{"pmid": "4356213", "title": "Adrenergic supersensitivity during ethanol withdrawal in the rat.", "content": "Adrenergic supersensitivity during ethanol withdrawal in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356213"}
{"pmid": "4356215", "title": "Experimental challenge of beef calves vaccinated intranasally with bovine myxovirus parainfluenza-3 vaccine.", "content": "Experimental challenge of beef calves vaccinated intranasally with bovine myxovirus parainfluenza-3 vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356215"}
{"pmid": "4356214", "title": "Interferon induction and suppression of solid tumor growth in rats by tilorone hydrochloride.", "content": "Interferon induction and suppression of solid tumor growth in rats by tilorone hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356214"}
{"pmid": "4356206", "title": "The work of the primary liver cancer research project: the differential diagnosis of primary malignant hepatoma in patients referred to the liver cancer unit.", "content": "The work of the primary liver cancer research project: the differential diagnosis of primary malignant hepatoma in patients referred to the liver cancer unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356206"}
{"pmid": "4356224", "title": "Hormaonal regulation of cyclic AMP.", "content": "Hormaonal regulation of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356224"}
{"pmid": "4356227", "title": "Cryosurgery and glomus jugulare tumors of the ear.", "content": "Cryosurgery and glomus jugulare tumors of the ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356227"}
{"pmid": "4356228", "title": "Primary intracranial germ cell tumours.", "content": "Primary intracranial germ cell tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356228"}
{"pmid": "4356229", "title": "Metastases and recurrences in nephroblastoma.", "content": "Metastases and recurrences in nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356229"}
{"pmid": "4356230", "title": "Radiation necrosis of the humerus. A report of three cases.", "content": "Radiation necrosis of the humerus. A report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356230"}
{"pmid": "4356231", "title": "Physical and chemical properties of respirable coal dust from two United States mines.", "content": "Physical and chemical properties of respirable coal dust from two United States mines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356231"}
{"pmid": "4356232", "title": "The determination of quartz in airborne respirable granite dust by infrared spectrophotometry.", "content": "The determination of quartz in airborne respirable granite dust by infrared spectrophotometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356232"}
{"pmid": "4356233", "title": "Pearly penile papules. Acral angiofibromas.", "content": "Pearly penile papules. Acral angiofibromas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356233"}
{"pmid": "4356234", "title": "Vincristine neurotoxicity and abnormal secretion of antidiuretic hormone.", "content": "Vincristine neurotoxicity and abnormal secretion of antidiuretic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356234"}
{"pmid": "4356236", "title": "The modified stuart medium. A common transport medium for Entamoeba histolytica and enteric bacteria. (Preliminary report).", "content": "The modified stuart medium. A common transport medium for Entamoeba histolytica and enteric bacteria. (Preliminary report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356236"}
{"pmid": "4356237", "title": "Different optimal temperatures for the biologic activity of rabbit and human lymphocytes in vitro.", "content": "Different optimal temperatures for the biologic activity of rabbit and human lymphocytes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356237"}
{"pmid": "4356238", "title": "Threonine-sensitive aspartokinase from Escherichia coli. Magnetic resonance and binding studies.", "content": "Threonine-sensitive aspartokinase from Escherichia coli. Magnetic resonance and binding studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356238"}
{"pmid": "4356239", "title": "Amino protons of cytosine. Chemical exchange, rotational exchange, and salt-induced proton magnetic resonance chemical shifts of aqueous 2',3'-cyclic cytidine monophosphate.", "content": "Amino protons of cytosine. Chemical exchange, rotational exchange, and salt-induced proton magnetic resonance chemical shifts of aqueous 2',3'-cyclic cytidine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356239"}
{"pmid": "4356241", "title": "Organization of the lipid phase in viral membranes. Effects of independent variation of the lipid and the protein composition.", "content": "Organization of the lipid phase in viral membranes. Effects of independent variation of the lipid and the protein composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356241"}
{"pmid": "4356240", "title": "Biosynthesis of the C18 family of cutin acids: omega-hydroxyoleic acid, omega-hydroxy-9,10-epoxystearic acid, 9,10,18-trihydroxystearic acid, and their delta12-unsaturated analogs.", "content": "Biosynthesis of the C18 family of cutin acids: omega-hydroxyoleic acid, omega-hydroxy-9,10-epoxystearic acid, 9,10,18-trihydroxystearic acid, and their delta12-unsaturated analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356240"}
{"pmid": "4356243", "title": "Lipid requirements for Rhodopsin regenerability.", "content": "Lipid requirements for Rhodopsin regenerability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356243"}
{"pmid": "4356242", "title": "Location of aromatic amino acid residues in bovine serum high-density lipoprotein.", "content": "Location of aromatic amino acid residues in bovine serum high-density lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356242"}
{"pmid": "4356244", "title": "The enzymic phosphorylation of N6-(delta 2-isopentenyl) adenosine in chick liver homogenates.", "content": "The enzymic phosphorylation of N6-(delta 2-isopentenyl) adenosine in chick liver homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356244"}
{"pmid": "4356245", "title": "Comparative study of molecular species of glycerolipids in sarcotubular membranes of skeletal muscle of rabbit, rat, chicken, and man.", "content": "Comparative study of molecular species of glycerolipids in sarcotubular membranes of skeletal muscle of rabbit, rat, chicken, and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356245"}
{"pmid": "4356246", "title": "Properties of inosinic acid dehydrogenase from Bacillus subtilis. I. Purification and physical properties.", "content": "Properties of inosinic acid dehydrogenase from Bacillus subtilis. I. Purification and physical properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356246"}
{"pmid": "4356247", "title": "Properties of inosinic acid dehydrogenase from Bacillus subtilis. II. Kinetic properties.", "content": "Properties of inosinic acid dehydrogenase from Bacillus subtilis. II. Kinetic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356247"}
{"pmid": "4356248", "title": "The effect of oxygen on metabolism in Astasia.", "content": "The effect of oxygen on metabolism in Astasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356248"}
{"pmid": "4356249", "title": "The reaction of N-ethylmaleimide with different forms of cytochrome oxidase.", "content": "The reaction of N-ethylmaleimide with different forms of cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356249"}
{"pmid": "4356250", "title": "Alpha-aminobutyronitrile as an intermediate in cyanide fixation by Rhizoctonia solani.", "content": "Alpha-aminobutyronitrile as an intermediate in cyanide fixation by Rhizoctonia solani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356250"}
{"pmid": "4356251", "title": "Diagnosis of Pneumocystis carinii pneumonia by transbronchoscopic lung biopsy.", "content": "Diagnosis of Pneumocystis carinii pneumonia by transbronchoscopic lung biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356251"}
{"pmid": "4356252", "title": "Separation of some pituitary proteohormones by disc-electrophoresis.", "content": "Separation of some pituitary proteohormones by disc-electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356252"}
{"pmid": "4356253", "title": "The hypothalamic areas involved in the control of mammotrophic and lactotrophic processes in sheep.", "content": "The hypothalamic areas involved in the control of mammotrophic and lactotrophic processes in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356253"}
{"pmid": "4356254", "title": "Glucocorticoid receptors in pituitary tumor cells. I. Cytosol receptors.", "content": "Glucocorticoid receptors in pituitary tumor cells. I. Cytosol receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356254"}
{"pmid": "4356255", "title": "The serum high density lipoproteins of Macacus rhesus. I. Isolation, composition, and properties.", "content": "The serum high density lipoproteins of Macacus rhesus. I. Isolation, composition, and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356255"}
{"pmid": "4356256", "title": "The serum high density lipoproteins of Macacus rhesus. II. Isolation, purification, and characterization of their two major polypeptides.", "content": "The serum high density lipoproteins of Macacus rhesus. II. Isolation, purification, and characterization of their two major polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356256"}
{"pmid": "4356257", "title": "Nuclear magnetic resonance studies on pyridine dinucleotides. I. The pH dependence of the carbon 13 nuclear magnetic resonance of nicotinamide adenine dinucleotide.", "content": "Nuclear magnetic resonance studies on pyridine dinucleotides. I. The pH dependence of the carbon 13 nuclear magnetic resonance of nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356257"}
{"pmid": "4356258", "title": "Structural bases for function in cytochromes c. An interpretation of comparative x-ray and biochemical data.", "content": "Structural bases for function in cytochromes c. An interpretation of comparative x-ray and biochemical data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356258"}
{"pmid": "4356259", "title": "Gluconeogenesis in isolated hepatic parenchymal cells.", "content": "Gluconeogenesis in isolated hepatic parenchymal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356259"}
{"pmid": "4356262", "title": "Evidence against the natural occurrence of alpha-nicotinamide adenine dinucleotide in Azotobacter vinelandii.", "content": "Evidence against the natural occurrence of alpha-nicotinamide adenine dinucleotide in Azotobacter vinelandii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356262"}
{"pmid": "4356260", "title": "The amino acid sequence of ovine pancreatic ribonuclease A.", "content": "The amino acid sequence of ovine pancreatic ribonuclease A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356260"}
{"pmid": "4356261", "title": "Adrenal mitochondrial cytochrome P-450 and cholesterol side chain cleavage activity. Differences in the response of the zona glomerulosa and zona fasciculata-reticularis to adrenocorticotropic hormone and its withdrawal.", "content": "Adrenal mitochondrial cytochrome P-450 and cholesterol side chain cleavage activity. Differences in the response of the zona glomerulosa and zona fasciculata-reticularis to adrenocorticotropic hormone and its withdrawal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356261"}
{"pmid": "4356263", "title": "Ferredoxins from Bacillus polymyxa. Low potential iron-sulfur proteins which appear to contain single four iron, four sulfur centers accepting a single electron on reduction.", "content": "Ferredoxins from Bacillus polymyxa. Low potential iron-sulfur proteins which appear to contain single four iron, four sulfur centers accepting a single electron on reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356263"}
{"pmid": "4356265", "title": "Prognostic typing in breast cancer. Further investigation of a necropsy series compared with recent surgical specimens.", "content": "Prognostic typing in breast cancer. Further investigation of a necropsy series compared with recent surgical specimens. A comparison of material from necropsy and surgical series has shown that breast carcinoma of cytological types II and III are rare. The majority of cases are of type I. Of the latter, tumours in TNM stage I were not found in the necropsy series, while infiltrating duct carcinomas of type I TNM stage II were also absent. This suggests that the possibility of surgical cure may be better in type I duct carcinomas in stage II than with other histological types. Prolonged survival in contrast to surgical cure was related to type III tumours irrespective of TNM stage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356265"}
{"pmid": "4356266", "title": "\"Sclerosing haemangioma\" of the lung: an alternative view of its development.", "content": "\"Sclerosing haemangioma\" of the lung: an alternative view of its development. ;Sclerosing haemangioma' is a name which has been applied to a group of uncommon benign pulmonary lesions characterized by their papillary nature, a sclerotic stroma containing lipid, and, in some cases, evidence of haemorrhage. There is little evidence that these lesions are really angiomatous. Studies of two examples removed surgically after being discovered as incidental radiographic findings, show that the cells lining the papillae have large vacuoles which contain whorled, electron-dense inclusions. These epithelial cells have the features of granular pneumonocytes, cells known to contain phospholipid. Both lipid and cholesterol are abundant in the stroma of both tumours and the lipid is distributed in a nodular fashion. Histochemically the lipid gives a strong reaction to stains for phospholipid and it is suggested that the lipid is derived, not from the haemorrhage, but is produced by the epithelial element of the tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356266"}
{"pmid": "4356264", "title": "Quantitative relations of fetal and maternal pitiutary-adrenal systems.", "content": "Quantitative relations of fetal and maternal pitiutary-adrenal systems. Even though certain aspects of the fetal pituitary-adrenal system have been extensively studied, much remains to be learned of its basic development and function. In the present work, the effect of maternal hypophysectomy upon quantitative pituitary-adrenal relations in mother and fetus was investigated in pregnant beagle dogs. At 57 days gestation in each of seven normal animals and seven animals 3 wk posthypophysectomy, a cannula for collection of adrenal effluent was placed in a single fetus in utero under halothane anesthesia. A timed fetal adrenal sample was obtained; ACTH (10 mU) was injected into the fetus; 3 min thereafter a second fetal adrenal sample was collected and fetal and maternal peripheral arterial samples were drawn. All fetuses and their adrenal glands were weighed. Concentrations of cortisol and corticosterone were determined by a modification of the double-isotope dilution derivative method of Kliman and Peterson. Mean peripheral cortisol concentrations in mother and fetus were 92 and 94 ng/ml, respectively (ratio 1.0), in normal pregnancies and 11 and 54 ng/ml, respectively (ratio 0.2), in maternal hypophysectomy pregnancies. Weights of fetal adrenal gland pairs of 32 and 44 mg, respectively, in normal and hypophysectomy pregnancies indicate increased fetal ACTH secretion in response to lowered circulating cortisol in the fetus secondary to maternal hypophysectomy. These data demonstrate the presence of an active pituitary-adrenal feedback mechanism in the dog fetus which is partly influenced by maternal pituitary-adrenal function. The shift in the maternal-fetal ratio of peripheral cortisol concentrations from 1.0 to 0.2 occasioned by maternal hypophysectomy neither supports nor rules out the presence of specific placental mechanisms affecting relative concentrations of cortisol in mother and fetus. It does suggest, however, that the relative steroid input into maternal and fetal compartments is one of the factors which influences such concentration ratios. Concentrations of cortisol were significantly higher in fetal adrenal effluent (pre-ACTH) than in fetal peripheral plasma in normal pregnancies, which demonstrates secretion of cortisol by the fetus and shows that corticosteroid of maternal origin does not lead to complete suppression of fetal pituitary-adrenal function. Cortisol secretion rates in response to exogenous ACTH were essentially the same in fetuses in normal and hypophysectomy pregnancies (132 and 128 ng/min, respectively). Thus, fetal adrenal responsiveness to ACTH, i.e., maximum secretory capacity, is not enhanced by increased ACTH stimulation sufficient to induce adrenal hypertrophy in the same fetuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356264"}
{"pmid": "4356267", "title": "The traditional oriental medicine and acupuncture therapy.", "content": "The traditional oriental medicine and acupuncture therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356267"}
{"pmid": "4356269", "title": "Methodology for separation of gangliosides from potential water-soluble precursors.", "content": "Methodology for separation of gangliosides from potential water-soluble precursors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356269"}
{"pmid": "4356271", "title": "Antagonistic effects of Myxococcus xanthus on fungi. II. Isolation and characterization of inhibitory lipid factors.", "content": "Antagonistic effects of Myxococcus xanthus on fungi. II. Isolation and characterization of inhibitory lipid factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356271"}
{"pmid": "4356270", "title": "D-galactosamine induced fatty liver. II. Analyses of hepatic lipid compositions.", "content": "D-galactosamine induced fatty liver. II. Analyses of hepatic lipid compositions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356270"}
{"pmid": "4356272", "title": "Whooping cough in Melbourne.", "content": "Whooping cough in Melbourne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356272"}
{"pmid": "4356273", "title": "The mechanism of initiation of parturition in the ewe.", "content": "The mechanism of initiation of parturition in the ewe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356273"}
{"pmid": "4356274", "title": "Protein kinases: aspects of their regulation and diversity.", "content": "Protein kinases: aspects of their regulation and diversity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356274"}
{"pmid": "4356275", "title": "The role of phospholipids in hormone activation of adenylate cyclase.", "content": "The role of phospholipids in hormone activation of adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356275"}
{"pmid": "4356276", "title": "Hormonal regulation of gene expression in mammary cells.", "content": "Hormonal regulation of gene expression in mammary cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356276"}
{"pmid": "4356277", "title": "Studies on luteinizing hormone and its subunits: development and application of a radioligand receptor assay and properties of the hormone-receptor interaction.", "content": "Studies on luteinizing hormone and its subunits: development and application of a radioligand receptor assay and properties of the hormone-receptor interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356277"}
{"pmid": "4356278", "title": "Androgen metabolism and mechanism of action in male pseudohermaphroditism: a study of testicular feminization.", "content": "Androgen metabolism and mechanism of action in male pseudohermaphroditism: a study of testicular feminization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356278"}
{"pmid": "4356280", "title": "Bicyclic phosphorus esters: high toxicity without cholinesterase inhibition.", "content": "Bicyclic phosphorus esters: high toxicity without cholinesterase inhibition. 4-Isopropyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane 1-oxide has a mouse intraperitoneal lethal dose, 50 percent effective, of 0.18 milligram per kilogram of body weight. Related compounds used by many chemical researchers are also highly toxic. Brain acetylcholinesterase inhibition is not involved in their mode of action. The structural similarity of these compounds to adenosine 3',5'-monophosphate (cyclic AMP) is of interest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356280"}
{"pmid": "4356282", "title": "Gas chromatographic analysis of drugs and drug metabolites in biological samples.", "content": "Gas chromatographic analysis of drugs and drug metabolites in biological samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356282"}
{"pmid": "4356281", "title": "Xenotropic viruses: murine leukemia viruses associated with NIH Swiss, NZB, and other mouse strains.", "content": "Xenotropic viruses: murine leukemia viruses associated with NIH Swiss, NZB, and other mouse strains. Murine leukemia virus activity is present in tissues from NIH Swiss and other mouse strains after cocultivation with nonvirus-yielding rat cells transformed by Harvey sarcoma virus. The resulting pseudotype sarcoma virus has the same type-specific coat as the virus previously isolated from New Zealand black (NZB) mice, and, like the NZB virus, it is unable to infect mouse cells. The results show that this NZB type virus is endogenous in other strains of mice and is xenotropic; that is, it grows only in cells foreign to the host. This is the first clear demonstration that NIH Swiss mice also carry indigenous infectious murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356281"}
{"pmid": "4356288", "title": "On the estimation of some demographic characteristics on a prehistoric population from the American Southwest.", "content": "On the estimation of some demographic characteristics on a prehistoric population from the American Southwest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356288"}
{"pmid": "4356289", "title": "A new enzymatic method for the determination of inorganic phosphate and its application to the nucleoside diphosphatase assay.", "content": "A new enzymatic method for the determination of inorganic phosphate and its application to the nucleoside diphosphatase assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356289"}
{"pmid": "4356290", "title": "Concentration and purification of two small RNA viruses: mycophage PS-1 and bacteriophage phi6.", "content": "Concentration and purification of two small RNA viruses: mycophage PS-1 and bacteriophage phi6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356290"}
{"pmid": "4356291", "title": "Interference by ascorbate-2-sulfate in the dinitrophenylhydrazine assay of ascorbic acid.", "content": "Interference by ascorbate-2-sulfate in the dinitrophenylhydrazine assay of ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356291"}
{"pmid": "4356292", "title": "The diurnal variation of peptidyl proline hydroxylase activity in different tissues of the rat.", "content": "The diurnal variation of peptidyl proline hydroxylase activity in different tissues of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356292"}
{"pmid": "4356293", "title": "Insulin degradation. 8. Protein thiols as co-substrates for glutathione-insulin transhydrogenase.", "content": "Insulin degradation. 8. Protein thiols as co-substrates for glutathione-insulin transhydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356293"}
{"pmid": "4356295", "title": "Degradation of thyroxine by microsomal particles from rat liver. II. Purification of Fe2+-dependent particles and some of their properties.", "content": "Degradation of thyroxine by microsomal particles from rat liver. II. Purification of Fe2+-dependent particles and some of their properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356295"}
{"pmid": "4356296", "title": "Occurrence and biosynthesis of adenosine 3',5'-cyclic monophosphate in isolated Avena etioplasts.", "content": "Occurrence and biosynthesis of adenosine 3',5'-cyclic monophosphate in isolated Avena etioplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356296"}
{"pmid": "4356297", "title": "Biosynthesis of NAD in Haemophilus haemoglobinophilus.", "content": "Biosynthesis of NAD in Haemophilus haemoglobinophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356297"}
{"pmid": "4356294", "title": "Studies on estrogen entry into uterine cells and on estradiol-receptor complex attachment to the nucleus--is the entry of estrogen into uterine cells a protein-mediated process?", "content": "Studies on estrogen entry into uterine cells and on estradiol-receptor complex attachment to the nucleus--is the entry of estrogen into uterine cells a protein-mediated process?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356294"}
{"pmid": "4356298", "title": "Myocardial adenosine kinase: activity and localization determined with rapid, radiometric assay.", "content": "Myocardial adenosine kinase: activity and localization determined with rapid, radiometric assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356298"}
{"pmid": "4356299", "title": "Iron-ATP, a by-product of acid extraction of whole blood or red blood cells.", "content": "Iron-ATP, a by-product of acid extraction of whole blood or red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356299"}
{"pmid": "4356300", "title": "Improved synthesis of 32P-labelled 3',5'-cyclic GMP and other 3',5'-cyclic ribo- and deoxyribonucleotides of high specific activity.", "content": "Improved synthesis of 32P-labelled 3',5'-cyclic GMP and other 3',5'-cyclic ribo- and deoxyribonucleotides of high specific activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356300"}
{"pmid": "4356301", "title": "The effects of delta 1-tetrahydrocannabinol on cyclic AMP levels in WI-38 fibroblasts.", "content": "The effects of delta 1-tetrahydrocannabinol on cyclic AMP levels in WI-38 fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356301"}
{"pmid": "4356302", "title": "Stimulation of purified muscle protein kinase by cyclic AMP and its butyrated derivatives.", "content": "Stimulation of purified muscle protein kinase by cyclic AMP and its butyrated derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356302"}
{"pmid": "4356303", "title": "Phosphoenolpyruvate:fructose phosphotransferase activity in whole cells and membrane vesicles of Arthrobacter pyridinolis.", "content": "Phosphoenolpyruvate:fructose phosphotransferase activity in whole cells and membrane vesicles of Arthrobacter pyridinolis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356303"}
{"pmid": "4356304", "title": "On the nature of the serum enzyme catalyzing paraoxon hydrolysis.", "content": "On the nature of the serum enzyme catalyzing paraoxon hydrolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356304"}
{"pmid": "4356305", "title": "Model discrimination and nonlinear parameter estimation in the analysis of the mechanism of action of beta-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides.", "content": "Model discrimination and nonlinear parameter estimation in the analysis of the mechanism of action of beta-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356305"}
{"pmid": "4356306", "title": "Alterations in the levels of peptide hydrolases and other enzymes in brush-border and soluble fractions of rat small intestinal mucosa during starvation and refeeding.", "content": "Alterations in the levels of peptide hydrolases and other enzymes in brush-border and soluble fractions of rat small intestinal mucosa during starvation and refeeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356306"}
{"pmid": "4356308", "title": "Inorganic pyrophosphate-phosphohydrolytic activity in human serum. Catalytic properties of the ionic species of PPi and MgPPi complexes.", "content": "Inorganic pyrophosphate-phosphohydrolytic activity in human serum. Catalytic properties of the ionic species of PPi and MgPPi complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356308"}
{"pmid": "4356307", "title": "Localization of 3-beta hydroxysteroid dehydrogenase in the inner membrane subfraction of rat testis mitochondria.", "content": "Localization of 3-beta hydroxysteroid dehydrogenase in the inner membrane subfraction of rat testis mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356307"}
{"pmid": "4356309", "title": "Polyphosphate phosphohydrolase from Endomyces magnusii.", "content": "Polyphosphate phosphohydrolase from Endomyces magnusii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356309"}
{"pmid": "4356310", "title": "Epinephrine- and prostaglandin-sensitive adenyl cyclase in mammary gland.", "content": "Epinephrine- and prostaglandin-sensitive adenyl cyclase in mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356310"}
{"pmid": "4356311", "title": "Interactions of succinate dehydrogenase with cyanide.", "content": "Interactions of succinate dehydrogenase with cyanide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356311"}
{"pmid": "4356312", "title": "Intracellular localization of superoxide dismutase and its relation to the distribution and mechanism of hydrogen peroxide-producting enzymes.", "content": "Intracellular localization of superoxide dismutase and its relation to the distribution and mechanism of hydrogen peroxide-producting enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356312"}
{"pmid": "4356313", "title": "Influence of pyrophosphate on the exchange of calcium and phosphate ions on hydroxyapatite.", "content": "Influence of pyrophosphate on the exchange of calcium and phosphate ions on hydroxyapatite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356313"}
{"pmid": "4356314", "title": "Active and passive immunity to bovine viral respiratory diseases in beef calves after shipment.", "content": "Active and passive immunity to bovine viral respiratory diseases in beef calves after shipment. Fifteen steers were vaccinated after shipment with a modified live virus vaccine containing infectious bovine rhinotracheitis (IBR), bovine virus diarrhea (BVD), and bovine myxovirus parainfluenza-3 (PI3), and 16 unvaccinated steers were kept as controls. Geometric mean titers one month after vaccination were highest to BVD, followed by PI3 and IBR. Weight gains were higher during 30 days after vaccination in the controls. One case of acute respiratory disease developed in one vaccinated calf. Revaccination 79 days after the first dose increased antibody to PI3 and BVD virus but not IBR. In a second trial, no clinical respiratory disease developed after shipment of 13 heifers that received an antibacterial-antiviral antiserum or in the 12 controls. Weight gains 30 days after shipment were identical in both groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356314"}
{"pmid": "4356315", "title": "Infectious bursal disease in New Brunswick.", "content": "Infectious bursal disease in New Brunswick. A flock of four week old chickens experienced a disease of sudden onset in which the only symptoms were those of depression shortly before death, and in which the predominant histological lesion was necrosis of lymphocytes in the bursa of Fabricius.A virus, designated strain Sk-1, was isolated from pooled bursal tissue of affected birds and was serologically identified as a strain of the infectious bursal agent. This virus was chloroform resistant, did not hemagglutinate guinea pig or chicken erythrocytes and did not produce a cytopathic effect in chick embryo tissue cultures. Equivocal results were obtained in filtration studies but the agent was less than 100nm in diameter. Four week old chicks inoculated with strain Sk-1 developed microscopic lesions in the bursa of Fabricius which were similar to those seen in the original field specimens. Inoculated chick embryos exhibited characteristic macroscopic lesions and necrosis of vascular tissue was a common histological change.A limited serological survey of local poultry flocks indicated that infection by this agent had occurred in four of the ten flocks examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356315"}
{"pmid": "4356316", "title": "Observations of cattle, goats and pigs after administration of synthetic interferon inducers and subsequent exposure to foot and mouth disease virus.", "content": "Observations of cattle, goats and pigs after administration of synthetic interferon inducers and subsequent exposure to foot and mouth disease virus. Polyriboinosinic-polyribocytidylic acid (poly [rI.rC]) was administered intravenously to 11 cattle and 13 goats in doses of 0.25 to 4.0, and 1.0 to 5.0 mg/kg, respectively. Subsequent exposure of these and untreated control animals to foot and mouth disease virus (FMDV) failed to demonstrate any differences in either the course or severity of the disease. Serum interferon was detected in cattle one hour after the intravenous administration of poly (rI.rC). Six pigs given 4, 20, or 100 mg/kg of itaconic-acrylic acid copolymer (IAA, HMW) intraperitoneally reacted clinically the same as six untreated control pigs after contact exposure to FMDV. Three pigs given 50, 100, or 200 mg/kg of divinyl ether-maleic anhydride copolymer (DVE/MA, pyran) intraperitoneally similarly failed to show any difference in clinical reaction from three untreated control pigs after intranasal instillation of FMDV. Three pigs given 100, 200 or 400 mg/kg of DVE/MA intraperitoneally developed rapid diffuse peritonitis causing the death of one in 48 hours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356316"}
{"pmid": "4356319", "title": "Outpatient management of chronic schizophrenics with fluphenazine enanthate (Prolixin enanthate): a clinical evaluation.", "content": "Outpatient management of chronic schizophrenics with fluphenazine enanthate (Prolixin enanthate): a clinical evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356319"}
{"pmid": "4356322", "title": "Electrophoretic characterization of bovine serum lipoproteins throughout gestation and lactation.", "content": "Electrophoretic characterization of bovine serum lipoproteins throughout gestation and lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356322"}
{"pmid": "4356323", "title": "Immune complex glomerulonephritis in one-year-old C57BL-6 mice induced by endogenous murine leukemia virus and erythrocyte antigens.", "content": "Immune complex glomerulonephritis in one-year-old C57BL-6 mice induced by endogenous murine leukemia virus and erythrocyte antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356323"}
{"pmid": "4356324", "title": "Quantitation of mouse mammary tumor virus (MTV) virions by radioimmunoassay.", "content": "Quantitation of mouse mammary tumor virus (MTV) virions by radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356324"}
{"pmid": "4356326", "title": "Production and properties of migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity.", "content": "Production and properties of migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356326"}
{"pmid": "4356325", "title": "Decreased epinephrine response of adenylate cyclase activity of lymphoid cells from immunodeficient pituitary dwarf mice.", "content": "Decreased epinephrine response of adenylate cyclase activity of lymphoid cells from immunodeficient pituitary dwarf mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356325"}
{"pmid": "4356327", "title": "Characterization of a second normal antigen that cross-reacts with CEA.", "content": "Characterization of a second normal antigen that cross-reacts with CEA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356327"}
{"pmid": "4356320", "title": "Separation and detection of 35S-labelled taurine, isethionic acid and sulfate.", "content": "Separation and detection of 35S-labelled taurine, isethionic acid and sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356320"}
{"pmid": "4356329", "title": "Unsuspected lymphosarcoma of the kidneys diagnosed as bilateral Wilms tumor.", "content": "Unsuspected lymphosarcoma of the kidneys diagnosed as bilateral Wilms tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356329"}
{"pmid": "4356328", "title": "The electromyogram in facial myokymia and hemifacial spasm.", "content": "The electromyogram in facial myokymia and hemifacial spasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356328"}
{"pmid": "4356330", "title": "Canine renal allografts hyperacute rejection: an experimental model for studies on treatment.", "content": "Canine renal allografts hyperacute rejection: an experimental model for studies on treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356330"}
{"pmid": "4356321", "title": "The subunits of L-glutamate decarboxylase from Clostridium perfringens.", "content": "The subunits of L-glutamate decarboxylase from Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356321"}
{"pmid": "4356331", "title": "Studies on the prevalence of Salmonella serotypes in nonhuman primates.", "content": "Studies on the prevalence of Salmonella serotypes in nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356331"}
{"pmid": "4356332", "title": "A simple method for determining erythrocyte survival in rats using slchromium.", "content": "A simple method for determining erythrocyte survival in rats using slchromium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356332"}
{"pmid": "4356333", "title": "Latent Pasteurella pneumotropica infection of the gnotobiotic and barrier-held rats.", "content": "Latent Pasteurella pneumotropica infection of the gnotobiotic and barrier-held rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356333"}
{"pmid": "4356334", "title": "Strain differences in the response of rats to repeated injections of pentobarbital sodium.", "content": "Strain differences in the response of rats to repeated injections of pentobarbital sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356334"}
{"pmid": "4356335", "title": "Variability of embryonic development in the rabbit at 19 to 168 hours after mating.", "content": "Variability of embryonic development in the rabbit at 19 to 168 hours after mating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356335"}
{"pmid": "4356338", "title": "The rabbit pyrogen test.", "content": "The rabbit pyrogen test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356338"}
{"pmid": "4356336", "title": "Development of a Pasteurella-free rabbit colony.", "content": "Development of a Pasteurella-free rabbit colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356336"}
{"pmid": "4356337", "title": "Mode of killing and plasma corticosterone concentrations in the rat.", "content": "Mode of killing and plasma corticosterone concentrations in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356337"}
{"pmid": "4356340", "title": "A safe and efficient handling device for wild rodents.", "content": "A safe and efficient handling device for wild rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356340"}
{"pmid": "4356339", "title": "A method for intragastric feeding of neonatal rats.", "content": "A method for intragastric feeding of neonatal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356339"}
{"pmid": "4356341", "title": "Apparatus facilitating intravenous injections in dogs.", "content": "Apparatus facilitating intravenous injections in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356341"}
{"pmid": "4356342", "title": "The hemogram and bone marrow profile of normal neonatal and weanling beagle dogs.", "content": "The hemogram and bone marrow profile of normal neonatal and weanling beagle dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356342"}
{"pmid": "4356343", "title": "Actinomycosis in a primate confirmed by fluorescent antibody technics in formalin fixed tissue.", "content": "Actinomycosis in a primate confirmed by fluorescent antibody technics in formalin fixed tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356343"}
{"pmid": "4356344", "title": "A rapid screening program for the diagnosis of Dirofilaria immitis infections in dogs.", "content": "A rapid screening program for the diagnosis of Dirofilaria immitis infections in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356344"}
{"pmid": "4356345", "title": "Hemoglobins, haptoglobins, and transferrins in beagles.", "content": "Hemoglobins, haptoglobins, and transferrins in beagles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356345"}
{"pmid": "4356346", "title": "A discrimination problem for restrained beagles.", "content": "A discrimination problem for restrained beagles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356346"}
{"pmid": "4356347", "title": "The miniature pig: a biomedical model for behavioral studies.", "content": "The miniature pig: a biomedical model for behavioral studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356347"}
{"pmid": "4356348", "title": "Urinary bladder carcinoma in a rhesus monkey (Macaca mulatta): a literature review and case report.", "content": "Urinary bladder carcinoma in a rhesus monkey (Macaca mulatta): a literature review and case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356348"}
{"pmid": "4356349", "title": "Self-mutilation following Innovar-Vet injection in the guinea pig.", "content": "Self-mutilation following Innovar-Vet injection in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356349"}
{"pmid": "4356350", "title": "Naturally-occurring and experimentally-induced arthritides in rodents: a review of the literature.", "content": "Naturally-occurring and experimentally-induced arthritides in rodents: a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356350"}
{"pmid": "4356351", "title": "Letter: Laboratory animal medicine.", "content": "Letter: Laboratory animal medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356351"}
{"pmid": "4356352", "title": "Effect of ethanol on cyclic AMP levels in the rat brain.", "content": "Effect of ethanol on cyclic AMP levels in the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356352"}
{"pmid": "4356358", "title": "The role of spinal cord facilitation in neurogenic bladder function.", "content": "The role of spinal cord facilitation in neurogenic bladder function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356358"}
{"pmid": "4356363", "title": "Structure-activity relationships in drug-induced pancreatic islet cell toxicity.", "content": "Structure-activity relationships in drug-induced pancreatic islet cell toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356363"}
{"pmid": "4356362", "title": "Subcellular localization of human placental aryl hydrocarbon hydroxylase.", "content": "Subcellular localization of human placental aryl hydrocarbon hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356362"}
{"pmid": "4356364", "title": "Action of black widow spider venom at insect neuromuscular junctions.", "content": "Action of black widow spider venom at insect neuromuscular junctions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356364"}
{"pmid": "4356372", "title": "The inactivation of foot-and-mouth disease virus by ethylenimine and propylenimine.", "content": "The inactivation of foot-and-mouth disease virus by ethylenimine and propylenimine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356372"}
{"pmid": "4356361", "title": "Localized neurogenic vasoconstriction of the basilar artery.", "content": "Localized neurogenic vasoconstriction of the basilar artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356361"}
{"pmid": "4356378", "title": "Indirect coulometric titration of biological electron transport components.", "content": "Indirect coulometric titration of biological electron transport components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356378"}
{"pmid": "4356377", "title": "Nucleoside phosphomonesterases: an hypothesis on their physiological role in sporulating bacteria.", "content": "Nucleoside phosphomonesterases: an hypothesis on their physiological role in sporulating bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356377"}
{"pmid": "4356376", "title": "Lateral line input to the crista cerebellaris in the eel. Field potentials and histology.", "content": "Lateral line input to the crista cerebellaris in the eel. Field potentials and histology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356376"}
{"pmid": "4356389", "title": "The respiratory chain of Azotobacter vinelandii. II. The effect of cyanide on cytochrome d.", "content": "The respiratory chain of Azotobacter vinelandii. II. The effect of cyanide on cytochrome d.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356389"}
{"pmid": "4356388", "title": "The long-term solubility of a stannous fluoride-zinc phosphate cement.", "content": "The long-term solubility of a stannous fluoride-zinc phosphate cement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356388"}
{"pmid": "4356375", "title": "Incidence of hepatitis associated antigen in chronic liver disease in Southern Italy.", "content": "Incidence of hepatitis associated antigen in chronic liver disease in Southern Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356375"}
{"pmid": "4356391", "title": "Purification of the human intestinal brush border membrane.", "content": "Purification of the human intestinal brush border membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356391"}
{"pmid": "4356390", "title": "Fusion of mammalian cells by unilamellar lipid vesicles: inflluence of lipid surface charge, fluidity and cholesterol.", "content": "Fusion of mammalian cells by unilamellar lipid vesicles: inflluence of lipid surface charge, fluidity and cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356390"}
{"pmid": "4356384", "title": "Inhibition of cyclic AMP formation and lipolysis in rat adipose tissue by nicotinic acid.", "content": "Inhibition of cyclic AMP formation and lipolysis in rat adipose tissue by nicotinic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356384"}
{"pmid": "4356385", "title": "Plasma lipoproteins of turkeys injected with a single dose of diethylstilbestrol.", "content": "Plasma lipoproteins of turkeys injected with a single dose of diethylstilbestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356385"}
{"pmid": "4356386", "title": "Quantitative studies on fibrinogen and low-density lipoprotein in human aortic intima.", "content": "Quantitative studies on fibrinogen and low-density lipoprotein in human aortic intima.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356386"}
{"pmid": "4356397", "title": "The reaction of ammonia with acylated disaccharides. X. Octa-O-benzoyl-lactose and other benzoyl derivatives of lactose.", "content": "The reaction of ammonia with acylated disaccharides. X. Octa-O-benzoyl-lactose and other benzoyl derivatives of lactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356397"}
{"pmid": "4356398", "title": "Studies of polysaccharide structure. I. A modification of the Smith degradation.", "content": "Studies of polysaccharide structure. I. A modification of the Smith degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356398"}
{"pmid": "4356387", "title": "Trial of an anabolic steroid (oxymetholone) in atherosclerosis with hyperlipoproteinaemia.", "content": "Trial of an anabolic steroid (oxymetholone) in atherosclerosis with hyperlipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356387"}
{"pmid": "4356399", "title": "Degradation of dextrans by an alpha-1,6-glucan glucohydrolase from Streptococcus mitis.", "content": "Degradation of dextrans by an alpha-1,6-glucan glucohydrolase from Streptococcus mitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356399"}
{"pmid": "4356401", "title": "The methanesulfonylation of 2-benzimidazolemethanol and alpha-(2-benzimidazolyl)benzyl alcohol.", "content": "The methanesulfonylation of 2-benzimidazolemethanol and alpha-(2-benzimidazolyl)benzyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356401"}
{"pmid": "4356400", "title": "The molecular structures of a glucan and a galactan synthesised by Prototheca zopfii.", "content": "The molecular structures of a glucan and a galactan synthesised by Prototheca zopfii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356400"}
{"pmid": "4356403", "title": "Alpha-fetoprotein and Australia antigen in primary liver cancer.", "content": "Alpha-fetoprotein and Australia antigen in primary liver cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356403"}
{"pmid": "4356396", "title": "Preliminary clinical trials of butocin (NSC-172755) in patients with generalized carcinoma of the breast.", "content": "Preliminary clinical trials of butocin (NSC-172755) in patients with generalized carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356396"}
{"pmid": "4356394", "title": "Chemotherapy of Morris hepatoma 3924A: correlation of size and weight of tumor and preliminary data with 5-fluoro-2'-deoxyuridine (5-FUDR; NSC-27640).", "content": "Chemotherapy of Morris hepatoma 3924A: correlation of size and weight of tumor and preliminary data with 5-fluoro-2'-deoxyuridine (5-FUDR; NSC-27640).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356394"}
{"pmid": "4356395", "title": "Effect of streptonigrin (NSC-45383) and analogs on oncornavirus replication and DNA polymerase activity.", "content": "Effect of streptonigrin (NSC-45383) and analogs on oncornavirus replication and DNA polymerase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356395"}
{"pmid": "4356410", "title": "Initiation of globin synthesis in rabbit reticulocyte cell-free systems: inhibition by double-stranded RNA.", "content": "Initiation of globin synthesis in rabbit reticulocyte cell-free systems: inhibition by double-stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356410"}
{"pmid": "4356411", "title": "Haemoglobin and polypeptide biosynthesis by polyribosomes and ribosomal subparticles.", "content": "Haemoglobin and polypeptide biosynthesis by polyribosomes and ribosomal subparticles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356411"}
{"pmid": "4356412", "title": "Structural alterations and content of nicotinamide-adenine nucleotides in skeletal muscle of rat in chronic experimental carbon disulfide intoxication.", "content": "Structural alterations and content of nicotinamide-adenine nucleotides in skeletal muscle of rat in chronic experimental carbon disulfide intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356412"}
{"pmid": "4356413", "title": "Structural aspects of experimental carbon disulfide neuropathy. I. Development of neurohistological changes in chronically intoxicated rats.", "content": "Structural aspects of experimental carbon disulfide neuropathy. I. Development of neurohistological changes in chronically intoxicated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356413"}
{"pmid": "4356414", "title": "Hair cell interactions in the statocyst of Hermissenda.", "content": "Hair cell interactions in the statocyst of Hermissenda. Hair cells in the statocyst of Hermissenda crassicornis respond to mechanical stimulation with a short latency (<2 ms) depolarizing generator potential that is followed by hyperpolarization and inhibition of spike activity. Mechanically evoked hyperpolarization and spike inhibition were abolished by cutting the static nerve, repetitive mechanical stimulation, tetrodotoxin (TTX), and Co(++). Since none of these procedures markedly altered the generator potential it was concluded that the hyperpolarization is an inhibitory synaptic potential and not a component of the mechanotransduction process. Intracellular recordings from pairs of hair cells in the same statocyst and in statocysts on opposite sides of the brain revealed that hair cells are connected by chemical and/or electrical synapses. All chemical interactions were inhibitory. Hyperpolarization and spike inhibition result from inhibitory interactions between hair cells in the same and in opposite statocysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356414"}
{"pmid": "4356415", "title": "The fibrous components of bovine ligamentum nuchae observed in the scanning electron microscope.", "content": "The fibrous components of bovine ligamentum nuchae observed in the scanning electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356415"}
{"pmid": "4356416", "title": "Strychnine, morphine and monamine depression.", "content": "Strychnine, morphine and monamine depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356416"}
{"pmid": "4356417", "title": "The effect of local anaesthetic agents on lipolysis by human adipose tissue.", "content": "The effect of local anaesthetic agents on lipolysis by human adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356417"}
{"pmid": "4356418", "title": "Effect of a highly purified phospholipase C on some electrophysiological properties of the frog muscle fibre membrane.", "content": "Effect of a highly purified phospholipase C on some electrophysiological properties of the frog muscle fibre membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356418"}
{"pmid": "4356419", "title": "The metabolism of (ureyl-14C)tolbutamide in vitro and in vivo in man.", "content": "The metabolism of (ureyl-14C)tolbutamide in vitro and in vivo in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356419"}
{"pmid": "4356424", "title": "Nursing care study: pancreatic dermatosis.", "content": "Nursing care study: pancreatic dermatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356424"}
{"pmid": "4356425", "title": "General model for the molecular events in synapses during learning.", "content": "General model for the molecular events in synapses during learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356425"}
{"pmid": "4356433", "title": "The histochemical mapping of \"chemical pathways\" in the central nervous system.", "content": "The histochemical mapping of \"chemical pathways\" in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356433"}
{"pmid": "4356432", "title": "The incidence of malignant tumours in the mouth-pharynx region in Sweden 1958-1967.", "content": "The incidence of malignant tumours in the mouth-pharynx region in Sweden 1958-1967.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356432"}
{"pmid": "4356431", "title": "Parthenogenesis in birds.", "content": "Parthenogenesis in birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356431"}
{"pmid": "4356444", "title": "Pseudomonas cytochrome c peroxidase. VII. Kinetics of the peroxidatic reaction mechanism.", "content": "Pseudomonas cytochrome c peroxidase. VII. Kinetics of the peroxidatic reaction mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356444"}
{"pmid": "4356445", "title": "Pseudomonas cytochrome c peroxidase. 8. The amino acid composition of the enzyme.", "content": "Pseudomonas cytochrome c peroxidase. 8. The amino acid composition of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356445"}
{"pmid": "4356447", "title": "Cerebrospinal fluid cytomorphology using cytocentrifugation.", "content": "Cerebrospinal fluid cytomorphology using cytocentrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356447"}
{"pmid": "4356448", "title": "The role of the platelet membrane in platelet function. II. 5-Hydroxytryptamine (serotonin) uptake.", "content": "The role of the platelet membrane in platelet function. II. 5-Hydroxytryptamine (serotonin) uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356448"}
{"pmid": "4356449", "title": "Eosinophilic Pelger-Huët anomaly with myeloproliferative disorder.", "content": "Eosinophilic Pelger-Huët anomaly with myeloproliferative disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356449"}
{"pmid": "4356451", "title": "Urine testing: a comparison of five current methods for detecting morphine.", "content": "Urine testing: a comparison of five current methods for detecting morphine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356451"}
{"pmid": "4356450", "title": "Isolation of viruses from single throat swabs processed for diagnosis of group A beta-hemolytic streptococci by fluorescent antibody technic.", "content": "Isolation of viruses from single throat swabs processed for diagnosis of group A beta-hemolytic streptococci by fluorescent antibody technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356450"}
{"pmid": "4356452", "title": "Pentose pathway and production of reduced nicotinamide adenine dinucleotide phosphate. A mechanism that may protect lungs from oxidants.", "content": "Pentose pathway and production of reduced nicotinamide adenine dinucleotide phosphate. A mechanism that may protect lungs from oxidants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356452"}
{"pmid": "4356446", "title": "Evidence for a human oncogenic virus.", "content": "Evidence for a human oncogenic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356446"}
{"pmid": "4356453", "title": "Demeclocycline-induced nephrogenic diabetes insipidus. In-vivo and in-vitro studies.", "content": "Demeclocycline-induced nephrogenic diabetes insipidus. In-vivo and in-vitro studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356453"}
{"pmid": "4356454", "title": "Letter: Asymptomatic cytomegalovirus mononucleosis.", "content": "Letter: Asymptomatic cytomegalovirus mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356454"}
{"pmid": "4356455", "title": "Endothelial inclusions and \"nuclear bodies\" in systemic lupus erythematosus.", "content": "Endothelial inclusions and \"nuclear bodies\" in systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356455"}
{"pmid": "4356456", "title": "Suppression of herpes simplex virus infection by phosphonoacetic acid.", "content": "Suppression of herpes simplex virus infection by phosphonoacetic acid. Disodium phosphonoacetate when administered orally or topically to mice experimentally infected with herpes simplex virus was able to significantly reduce the mortality associated with the agent. In addition, this compound was able to reduce herpesvirus lesions on the corneas of infected rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356456"}
{"pmid": "4356457", "title": "Inactivation of Clostridium perfringens type A spores at ultrahigh temperatures.", "content": "Inactivation of Clostridium perfringens type A spores at ultrahigh temperatures. The inactivation of Clostridium perfringens type A spores (three strains of different heat resistances) at ultrahigh temperatures was studied. Aqueous spore suspensions were heated at 85 to 135 C by the capillary tube method. When survivors were enumerated on the standard plating medium, the spores appeared to have been rapidly inactivated at temperatures above 100 C. The addition of lysozyme to the plating medium did not affect the recovery of spores surviving the early stages of heating, but lysozyme was required for maximal recovery of spores surviving extended heat treatments. The percentage of survivors requiring lysozyme for colony formation increased greatly with longer exposure times or increasing treatment temperature. Time-survivor curves indicated that each spore suspension was heterogeneous with respect to the heat resistance of spore outgrowth system or in the sensitivity of the spores to lysozyme. Recovery of survivors on the lysozyme containing medium revealed greater heat resistance for one strain than has been reported for spores of many mesophilic aerobes and anaerobes. The spores of all three strains were more resistant to heat inactivation when suspended in phosphate buffer, but a greater percentage of the survivors required lysozyme for colony formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356457"}
{"pmid": "4356459", "title": "Silica gel medium for enumeration of petroleumlytic microorganisms in the marine environment.", "content": "Silica gel medium for enumeration of petroleumlytic microorganisms in the marine environment. A silica gel medium was developed for the enumeration of petroleumlytic microorganisms in the marine environment. The medium was satisfactorily used for the investigation of the vertical distribution of bacteria in seawater from the surface to 1,000 m depth of western north Pacific central water as well as the neritic region of Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356459"}
{"pmid": "4356458", "title": "Sand beach bacteria: enumeration and characterization.", "content": "Sand beach bacteria: enumeration and characterization. Bacteria in the water-saturated sand of a relatively unpolluted sand beach were enumerated by direct microscope and viable counting. The number of interstitial bacteria was estimated to be a significant fraction of the total number of bacteria present. Three hundred sixty-two strains were isolated and submitted to cultural and biochemical tests. Fermentational abilities and the production of indole suggested that a significant number of these bacteria were symbiotically associated with resident metazoans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356458"}
{"pmid": "4356460", "title": "Direct immunofluorescence test for the diagnosis of genital herpesvirus infections.", "content": "Direct immunofluorescence test for the diagnosis of genital herpesvirus infections. Herpetic lesions of the genitalia may be confused clinically with other ulcerative, genital lesions. Direct immunofluorescence (FA) provides a rapid method of diagnosis, and the utility of this method for the diagnosis of genital ulcers was examined. One hundred and ten patients with genital lesions were examined by darkfield for syphilis and by FA and culture for herpes simplex virus (HSV) infections. Satisfactory samples were obtained from 102 patients, of which 81 were clinically suspected cases of HSV. Acetone-fixed slides of scrapings of ulcerative lesions were stained with conjugated antiserum prepared in rabbits against HSV type 2. HSV was isolated from 73% of specimens of suspected herpetic lesions, and 77% of these specimens were positive by FA. Nine percent were positive by FA only and these were not thought to represent false positives. Five percent were positive by culture only. A comparison of clinical diagnoses with laboratory findings revealed that 4% of the cases were misdiagnosed when only the clinical evaluation was considered. The data suggest that the inclusion of a diagnostic FA test for HSV along with the darkfield examination may be useful for differentiating the etiological agents of ulcerative, genital lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356460"}
{"pmid": "4356461", "title": "In vitro production of Clostridium perfringens enterotoxin and its detection by reversed passive hemagglutination.", "content": "In vitro production of Clostridium perfringens enterotoxin and its detection by reversed passive hemagglutination. The reversed passive hemagglutination (RPHA) test yielded a positive reaction in 2 h with as little as 0.5 ng of purified Clostridium perfringens enterotoxin (CPE) per ml as well as with cultures of some C. perfringens grown in Duncan-Strong (DS) medium. This method is the most sensitive, the simplest, and the fastest among all reported. The time course of CPE production of Clostridium perfringens NCTC 8798 in DS was investigated by RPHA. CPE in culture was detectable at 4 h, increased gradually, reached a maximum at 12 to 14 h, and remained at a high level of 20 mug/ml through 48 h of incubation. CPE synthesized within cells is released easily by sonic disruption of young cultures and by aging the cultures 20 h or more. Heat shock of the cell inoculum was essential for CPE production by C. perfringens in DS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356461"}
{"pmid": "4356462", "title": "Biodegradation of o-benzyl-p-chlorophenol.", "content": "Biodegradation of o-benzyl-p-chlorophenol. The extent of biodegradation of o-benzyl-p-chlorophenol, marketed as a germicide under the name Santophen((R)) 1 (Monsanto Co.), in river water, sewage, and activated sludge was determined. Biodegradation was assessed by use of a colorimetric procedure for phenolic materials, carbon analysis, and CO(2) evolution. In unacclimated river water, 0.1 mg of Santophen 1 per liter was degraded within 6 days. In sewage, 0.5 and 1.0 mg/liter levels of Santophen 1 were degraded in 1 day. Acclimated activated sludge achieved 80% biodegradation of 1.0 mg/liter Santophen 1 in 8 h and 100% in 24 h. When effluent from a semicontinuous activated sludge unit, acclimated to 20 mg of Santophen 1 per liter was used as the inoculum for the CO(2) evolution procedure, 60% of the total theoretical CO(2) was evolved from Santophen 1. Based on the results of these studies, indicating Santophen 1 to be readily biodegraded in at least four biological systems, the continued use of present levels of Santophen 1 should present no significant environmental problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356462"}
{"pmid": "4356463", "title": "Quantitative extraction of adenosine triphosphate from cultivable and host-grown microbes: calculation of adenosine triphosphate pools.", "content": "Quantitative extraction of adenosine triphosphate from cultivable and host-grown microbes: calculation of adenosine triphosphate pools. EXISTING DATA ON ADENOSINE TRIPHOSPHATE (ATP) POOLS IN MICROBES ARE DEFICIENT FOR TWO REASONS: (i) incomplete extractions of ATP, and (ii) the failure to take into account that the adverse effects of extracting procedures on standard ATP exert analogous effects on the ATP released from bacterial cells. Methods for correcting observed yields and calculating ATP pools have been demonstrated. Three bacterial species were used in the studies on extraction of ATP: Escherichia coli, Mycobacterium phlei, and Mycobacterium lepraemurium. Perchloric acid and n-butanol were disqualified because of their failure to extract total bacterial ATP even from E. coli and because of inconvenient procedures. The new extraction procedure had minimal effects on standard ATP, liberated 100% of the ATP pools from the three representative species of microbes, and caused no ionic imbalance or quenching of bioluminescence. This method involves vortexing of cell suspensions for 10 s with 23% chloroform (vol/vol), heating at 98 C for the required time (E. coli, 3 min; M. phlei, 5 min; M. lepraemurium, 10 min) and then 1 min at 98 C with vacuum to dry the samples. Heat or chloroform alone may suffice for some microbes and release total ATP from plant and animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356463"}
{"pmid": "4356464", "title": "Complement-fixing antigens produced by varicella-zoster virus in tissue culture.", "content": "Complement-fixing antigens produced by varicella-zoster virus in tissue culture. The complement-fixing antigens present in tissue cultures infected with varicella-zoster virus were separated into four components. There were (i) a cell-free soluble antigen, (ii) a cell-associated soluble antigen, (iii) a cell membrane-associated antigen, and (iv) a virion antigen. All four antigens were reactive with sera from patients with varicella or zoster, and about 90% of the total complement-fixing activity was found to be nonvirion associated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356464"}
{"pmid": "4356465", "title": "Medium for the selective enumeration of lactic acid bacteria from foods.", "content": "Medium for the selective enumeration of lactic acid bacteria from foods. A nitrite actidione polymyxin agar was developed for the enumeration of lactic acid bacteria. It was effective in recovering organisms from pure cultures and from foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356465"}
{"pmid": "4356466", "title": "Large-scale purification of ribonucleic acid tumor viruses by use of continuous-flow density gradient centrifugation.", "content": "Large-scale purification of ribonucleic acid tumor viruses by use of continuous-flow density gradient centrifugation. This report describes a 200- to 300-fold increase in the quantity of ribonucleic acud tumor virus particles previously isolated at one time by zonal centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356466"}
{"pmid": "4356468", "title": "Enterovirus recovery with vegetable floc.", "content": "Enterovirus recovery with vegetable floc. A lettuce floc was prepared and used for recovering enterovirus from an aqueous suspension. The method is simple, and the adsorption of coxsackievirus B5, echovirus 7, and poliovirus 1 is quantitative. The virus-floc complex may be removed from aqueous suspension by low-speed centrifugation and dissolved at an alkaline pH in a small volume of water; virus is then available for assay on cultured cells. Flocs from some other green vegetables also possess the property of virus adsorption", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356468"}
{"pmid": "4356467", "title": "Comparison of methods for the recovery of virus inoculated into ground beef.", "content": "Comparison of methods for the recovery of virus inoculated into ground beef. Various methods for the recovery of virus inoculated into ground beef were investigated in an attempt to develop a sensitive system that could be used to detect viral contaminants in market foods. A 100-g sample, inoculated with poliovirus 1, was suspended in 150 to 900 ml of Eagle minimum essential medium, pH 8.5, and mixed in either plastic bags or plastic cups on a mechanical shaker. The particulate materials were removed by means of cheese cloth, glass wool, woven fiber glass, or low-speed centrifugation. Large volumes of fluid were concentrated by ultrafiltration. Microbiological contamination was controlled by high antibiotic concentrations or by filtration. Quantitative plaque-forming-unit recovery of the virus was determined by utilizing an agar overlay technique on Vero cell cultures. The data indicated that from 20 to 50% of the seeded virus could be recovered from a 100-g sample of ground beef. The glass wool and woven fiber glass methods were the most effective, with recovery of approximately 50% of the inoculated virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356467"}
{"pmid": "4356469", "title": "Isolation and characterization of corynebacteria from burned children.", "content": "Isolation and characterization of corynebacteria from burned children. A total of 221 strains of corynebacteria were isolated and characterized by methods which included tests encompassing five schemes proposed for grouping cutaneous diphtheroids. Seventy-one strains (group I) were isolated from the hospital air in patient areas and from the normal skins of children admitted for reconstructive surgery of old healed burns and from the normal skins of nursing personnel. One hundred and fifty strains (group II) were isolated from various clinical specimens and from normal skins of a population of acutely burned children. The majority of the strains in group I were lipophilic and contained the largest number of fluorescent strains. Among the group II strains, there was a subgroup which was nonsusceptible to oxacillin, lincomycin, erythromycin, and kanamycin and also had in common the fermentation of glucose and galactose, reduction of both nitrate and nitrite, and growth on 40% bile agar. These strains were the most commonly recognized types isolated from acutely burned patients and possibly originated from the patient's intestinal tract. Data indicated that the air was not a means of transmission for these corynebacteria among acute patients. Corynebacteria were isolated from 11% of the burn wound cultures by using a selective medium but were found in 66% of the acute patients. Over 90% of the strains in groups I and II did not conform sufficiently with described characteristics of common human indigenous corynebacteria to be accurately speciated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356469"}
{"pmid": "4356470", "title": "Complement-fixation analysis of four subtypes of foot-and-mouth disease virus type A.", "content": "Complement-fixation analysis of four subtypes of foot-and-mouth disease virus type A. Complement-fixation patterns were established for four subtypes of foot-and-mouth disease virus by block assays against homologous and heterologous antiserum. Inhibition of fixation by excess antigen was observed in most homologous systems but rarely in the heterologous systems. The heterologous antibody titers were, in all instances, considerably lower than those for the homologous systems. Although relatively high dilutions of antiserum may be desirable for subtyping, higher concentrations of antibody should be used for determining serological types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356470"}
{"pmid": "4356471", "title": "Microcomplement-fixation inhibition: a rapid and economical test to detect non-complement-fixing antibodies.", "content": "Microcomplement-fixation inhibition: a rapid and economical test to detect non-complement-fixing antibodies. Complement-fixation inhibition test was adapted to the microtiter system. When cat and monkey non-complement-fixing antibody were used, the microtest was shown to be as sensitive as the conventional tube complement-fixation inhibition test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356471"}
{"pmid": "4356472", "title": "Plaque assay for polyoma virus on primary mouse kidney cell cultures.", "content": "Plaque assay for polyoma virus on primary mouse kidney cell cultures. A plaque assay for polyoma virus using primary baby mouse kidney cells is reported.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356472"}
{"pmid": "4356473", "title": "Serum from schizophrenic patients. Effect on cellular lactate stimulation and tryptophan uptake.", "content": "Serum from schizophrenic patients. Effect on cellular lactate stimulation and tryptophan uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356473"}
{"pmid": "4356474", "title": "Effect of vestibular and auditory stimulation on the REMs of REM sleep in autistic children.", "content": "Effect of vestibular and auditory stimulation on the REMs of REM sleep in autistic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356474"}
{"pmid": "4356475", "title": "Depression, psychopathy, and herpesvirus type I antibodies. Lack of relationship.", "content": "Depression, psychopathy, and herpesvirus type I antibodies. Lack of relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356475"}
{"pmid": "4356479", "title": "Electron microscope observation of viruslike particles in comedocarcinoma of the human breast.", "content": "Electron microscope observation of viruslike particles in comedocarcinoma of the human breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356479"}
{"pmid": "4356480", "title": "Assessment of significance of proportions of intraductal and infiltrating tumor growth in ductal carcinoma of the breast.", "content": "Assessment of significance of proportions of intraductal and infiltrating tumor growth in ductal carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356480"}
{"pmid": "4356481", "title": "Light microscopic identification of the ribosome-lamella complex in \"hairy cells\" of leukemic reticuloendotheliosis.", "content": "Light microscopic identification of the ribosome-lamella complex in \"hairy cells\" of leukemic reticuloendotheliosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356481"}
{"pmid": "4356482", "title": "Ultimobranchial thyroid neoplasms in bulls. A syndrome resembling medullary thyroid carcinoma in man.", "content": "Ultimobranchial thyroid neoplasms in bulls. A syndrome resembling medullary thyroid carcinoma in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356482"}
{"pmid": "4356483", "title": "Mesenchymal chondrosarcoma. A study of the ultrastructure.", "content": "Mesenchymal chondrosarcoma. A study of the ultrastructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356483"}
{"pmid": "4356484", "title": "A radiation-induced breast cancer.", "content": "A radiation-induced breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356484"}
{"pmid": "4356485", "title": "Turnover of cholesteryl esters in plasma low-density and high-density lipoproteins in familial hyperbetalipoproteinaemia.", "content": "Turnover of cholesteryl esters in plasma low-density and high-density lipoproteins in familial hyperbetalipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356485"}
{"pmid": "4356487", "title": "On the role of food vacuole formation in the uptake of dissolved nutrients by Tetrahymena.", "content": "On the role of food vacuole formation in the uptake of dissolved nutrients by Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356487"}
{"pmid": "4356488", "title": "Two-dimensional electrophoresis of proteins of citric acid nuclei prepared with aid of a Tissumizer.", "content": "Two-dimensional electrophoresis of proteins of citric acid nuclei prepared with aid of a Tissumizer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356488"}
{"pmid": "4356489", "title": "Studies on the uptake and metabolism of adenosine 3':5'-cyclic monophosphate and N6,O2-dibutyryl 3':5'-cyclic adenosine monophosphate in sea urchin eggs.", "content": "Studies on the uptake and metabolism of adenosine 3':5'-cyclic monophosphate and N6,O2-dibutyryl 3':5'-cyclic adenosine monophosphate in sea urchin eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356489"}
{"pmid": "4356490", "title": "Does the activation of succinate dehydrogenase affect the phosphorylating system in sub mitochondrial particles?", "content": "Does the activation of succinate dehydrogenase affect the phosphorylating system in sub mitochondrial particles?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356490"}
{"pmid": "4356492", "title": "Quantitation of acid phosphatase and aryl sulphatase in rat hepatic parenchymal and kupffer cells.", "content": "Quantitation of acid phosphatase and aryl sulphatase in rat hepatic parenchymal and kupffer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356492"}
{"pmid": "4356491", "title": "Constraints on the mechanism of reduction of molecular oxygen by cytochrome oxidase under coupled conditions.", "content": "Constraints on the mechanism of reduction of molecular oxygen by cytochrome oxidase under coupled conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356491"}
{"pmid": "4356493", "title": "LH-RH stimulated gonadotropin release mediated by two distinct pituitary receptors.", "content": "LH-RH stimulated gonadotropin release mediated by two distinct pituitary receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356493"}
{"pmid": "4356494", "title": "Mitochondrial protein synthesis and cyanide-resistant respiration in copper-depleted, cytochrome oxidase-deficient Neurospora crassa.", "content": "Mitochondrial protein synthesis and cyanide-resistant respiration in copper-depleted, cytochrome oxidase-deficient Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356494"}
{"pmid": "4356495", "title": "Aminopropyl glass and its p-phenylene diisothiocyanate derivative, a new support in solid-phase Edman degradation of peptides and proteins.", "content": "Aminopropyl glass and its p-phenylene diisothiocyanate derivative, a new support in solid-phase Edman degradation of peptides and proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356495"}
{"pmid": "4356496", "title": "Changes in membrane function and chromatin template activity in diploid and transformed cells in culture.", "content": "Changes in membrane function and chromatin template activity in diploid and transformed cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356496"}
{"pmid": "4356498", "title": "Fatty acid composition of plasma lipoproteins in control subjects and in patients with malabsorption.", "content": "Fatty acid composition of plasma lipoproteins in control subjects and in patients with malabsorption. The fatty acid composition of cholesterol (cholesteryl) ester, triglyceride, and lecithin has been investigated in whole plasma and individual lipoproteins of healthy control subjects, of patients with malabsorption, and also of patients without malabsorption. The results show a decreased proportion of the essential fatty acid linoleic acid in all three lipid classes in both groups of patients as compared with the healthy controls. This abnormality was more marked in the malabsorbers, especially those with steatorrhoea secondary to intestinal resection. Unequivocal biochemical evidence of essential fatty acid deficiency, as indicated by the appearance of 5, 8, 11 eicosatrienoic acid in plasma lecithin, was observed in two patients, both of whom had undergone major intestinal resections. The results suggest that intestinal resection predisposes to the development of essential fatty acid deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356498"}
{"pmid": "4356500", "title": "NMR spectroscopy: antibiotic interactions with phospholipids.", "content": "NMR spectroscopy: antibiotic interactions with phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356500"}
{"pmid": "4356499", "title": "Relative efficiency of cell cultures for detection of viruses.", "content": "Relative efficiency of cell cultures for detection of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356499"}
{"pmid": "4356501", "title": "Rapid quantitative GLC analysis of digoxin.", "content": "Rapid quantitative GLC analysis of digoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356501"}
{"pmid": "4356502", "title": "Effect of addition of sodium salts to salicylic acid--cetrimide system.", "content": "Effect of addition of sodium salts to salicylic acid--cetrimide system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356502"}
{"pmid": "4356503", "title": "The phospholipid composition of human spermatozoa and seminal plasma.", "content": "The phospholipid composition of human spermatozoa and seminal plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356503"}
{"pmid": "4356504", "title": "Renin release in anesthetized rats.", "content": "Renin release in anesthetized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356504"}
{"pmid": "4356505", "title": "Studies on the metabolism of aldosterone in chronic renal failure and anephric man.", "content": "Studies on the metabolism of aldosterone in chronic renal failure and anephric man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356505"}
{"pmid": "4356506", "title": "Dynamic studies of aldosterone in anephric man.", "content": "Dynamic studies of aldosterone in anephric man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356506"}
{"pmid": "4356515", "title": "Congenital varicella-zoster infection related to maternal disease in early pregnancy.", "content": "Congenital varicella-zoster infection related to maternal disease in early pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356515"}
{"pmid": "4356518", "title": "Pentobarbital: selective depression of excitatory postsynaptic potentials.", "content": "Pentobarbital: selective depression of excitatory postsynaptic potentials. The effects of pentobarbital (Nembutal) on synaptic transmission and postsynaptic potentials were studied by the use of several invertebrate preparations. Pentobarbital selectively and reversibly depressed both excitatory postsynaptic potentials and sodium-dependent postsynaptic responses to putative excitatory transmitters without affecting either inhibitory postsynaptic potentials or chloride- and potassium-dependent postsynaptic responses to putative transmitters. A selective depression of postsynaptic excitatory events was also observed with other central nervous system depressants (ethanol, chloroform, chloralose, diphenylhydantoin, and urethane). The results suggest that central and peripheral depression observed during general anesthesia is due to a selective depression of excitatory synaptic events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356518"}
{"pmid": "4356519", "title": "Effects of dibutyryl cyclic AMP on restoration of function of damaged sciatic nerve in rats.", "content": "Effects of dibutyryl cyclic AMP on restoration of function of damaged sciatic nerve in rats. In two experiments, the sciatic nerve of rats was either crushed or hemisected, and N(6),O(2)-dibutyryl adenosine 3',5'-monophosphate or saline was injected intramuscularly near the site of the lesion. In both types of nerve damage, the sensorimotor functions of animals treated with N(6),O(2)-dibutyryl adenosine 3',5'-monophosphate returned earlier than did those of saline-treated control animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356519"}
{"pmid": "4356520", "title": "Hypertensive action of 18-hydroxydeoxycorticosterone.", "content": "Hypertensive action of 18-hydroxydeoxycorticosterone. 18-Hydroxydeoxycorticosterone is an adrenal steroid hormone causing salt and water retention and is secreted in greatly increased amounts in response to the pituitary hormone adrenocorticotropic hormone. Its production is abnormally high in some forms of hypertension in man and rat. Direct proof that 18-hydroxydeoxycorticosterone is capable of causing hypertension is present. Daily subcutaneous injections of 200 micrograms, a low physiological dose, significantly increase the blood pressure of unilaterally nephrectomized saline-treated rats after 2 weeks. This strengthens the hypothesis that 18-hydroxydeoxycorticosterone contributes to the etiology of hypertension, possibly by a mechanism involving stressinduced release of adrenocorticotropic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356520"}
{"pmid": "4356521", "title": "Treatment of acromegaly by stereotaxic cryohypophysectomy.", "content": "Treatment of acromegaly by stereotaxic cryohypophysectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356521"}
{"pmid": "4356523", "title": "Gonadal dysgenesis: the XY variant.", "content": "Gonadal dysgenesis: the XY variant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356523"}
{"pmid": "4356522", "title": "Current concepts in diagnosis: electromyography in the diagnosis of neuromuscular disease.", "content": "Current concepts in diagnosis: electromyography in the diagnosis of neuromuscular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356522"}
{"pmid": "4356525", "title": "Polio and Coxsackievirus antibodies of New Guinean children.", "content": "Polio and Coxsackievirus antibodies of New Guinean children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356525"}
{"pmid": "4356524", "title": "Amoebic liver abscess in eastern Uttar Pradesh, India.", "content": "Amoebic liver abscess in eastern Uttar Pradesh, India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356524"}
{"pmid": "4356526", "title": "Effect of succinylcholine on single motor end-plates in man.", "content": "Effect of succinylcholine on single motor end-plates in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356526"}
{"pmid": "4356527", "title": "A study of the invasive growth of malignant tumors. II. Ultrastructural features of the metastatic growth of Yoshida ascites hepatoma 7974 in the rat brain.", "content": "A study of the invasive growth of malignant tumors. II. Ultrastructural features of the metastatic growth of Yoshida ascites hepatoma 7974 in the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356527"}
{"pmid": "4356528", "title": "Cell recognition and phagocytosis of SV40 transformed cell.", "content": "Cell recognition and phagocytosis of SV40 transformed cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356528"}
{"pmid": "4356529", "title": "Proposed standard methodology for the evaluation of silicosis hazards.", "content": "Proposed standard methodology for the evaluation of silicosis hazards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356529"}
{"pmid": "4356530", "title": "Defective interfering viruses.", "content": "Defective interfering viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356530"}
{"pmid": "4356531", "title": "The EB virus.", "content": "The EB virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356531"}
{"pmid": "4356532", "title": "Inhibition of gluconeogenesis in vitro by a metabolite of hypoglycin.", "content": "Inhibition of gluconeogenesis in vitro by a metabolite of hypoglycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356532"}
{"pmid": "4356533", "title": "The cyclic AMP receptor of Escherichia coli: immunological studies in extracts of Escherichia coli and other organisms.", "content": "The cyclic AMP receptor of Escherichia coli: immunological studies in extracts of Escherichia coli and other organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356533"}
{"pmid": "4356534", "title": "Progesterone receptor associated with the \"melanosome\" fraction of Pleurodeles waltlii oocytes (Urodela amphibian).", "content": "Progesterone receptor associated with the \"melanosome\" fraction of Pleurodeles waltlii oocytes (Urodela amphibian).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356534"}
{"pmid": "4356535", "title": "Stimulation by insulin of ornithine decarboxylase activity in cultured mammary tissue.", "content": "Stimulation by insulin of ornithine decarboxylase activity in cultured mammary tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356535"}
{"pmid": "4356536", "title": "Isolation and characterization of fucose sulfate from jelly coat glycoprotein of sea urchin egg.", "content": "Isolation and characterization of fucose sulfate from jelly coat glycoprotein of sea urchin egg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356536"}
{"pmid": "4356537", "title": "The physical chemistry of hemes. II. Electron paramagnetic resonance study of the interaction of some iron(3)-porphyrins with fluoride ion in dimethylformamide.", "content": "The physical chemistry of hemes. II. Electron paramagnetic resonance study of the interaction of some iron(3)-porphyrins with fluoride ion in dimethylformamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356537"}
{"pmid": "4356538", "title": "Adult rat brain synaptic vesicles. II. Lipid composition.", "content": "Adult rat brain synaptic vesicles. II. Lipid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356538"}
{"pmid": "4356539", "title": "Nuclear envelope isolation in peas.", "content": "Nuclear envelope isolation in peas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356539"}
{"pmid": "4356540", "title": "The asymmetric distribution of phospholipids in the human red cell membrane. A combined study using phospholipases and freeze-etch electron microscopy.", "content": "The asymmetric distribution of phospholipids in the human red cell membrane. A combined study using phospholipases and freeze-etch electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356540"}
{"pmid": "4356541", "title": "A study on phospholipid exchange proteins present in the soluble fractions of beef liver and brain.", "content": "A study on phospholipid exchange proteins present in the soluble fractions of beef liver and brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356541"}
{"pmid": "4356543", "title": "DNA methylation in normal and tumour virus-transformed cells in tissue culture. I. The level of DNA methylation in BHK21 cells and in BHK21 cells transformed by polyoma virus (PyY cells).", "content": "DNA methylation in normal and tumour virus-transformed cells in tissue culture. I. The level of DNA methylation in BHK21 cells and in BHK21 cells transformed by polyoma virus (PyY cells).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356543"}
{"pmid": "4356542", "title": "Studies on the relationship between adenylate cyclase activity and calcium transport by cardiac sarcotubular membranes.", "content": "Studies on the relationship between adenylate cyclase activity and calcium transport by cardiac sarcotubular membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356542"}
{"pmid": "4356545", "title": "Increased incidence of lung metastases following treatment of rats bearing hepatomas with irradiated tumour cells and the benefical effect of Corynebacterium parvum in this system.", "content": "Increased incidence of lung metastases following treatment of rats bearing hepatomas with irradiated tumour cells and the benefical effect of Corynebacterium parvum in this system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356545"}
{"pmid": "4356544", "title": "Antiviral activity of polynucleotides: poly(2'-fluoro-2'-deoxyuridylic acid).", "content": "Antiviral activity of polynucleotides: poly(2'-fluoro-2'-deoxyuridylic acid).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356544"}
{"pmid": "4356546", "title": "Radioimmunoassay of melanocytes-stimulating hormone (beta-MSH) in human plasma.", "content": "Radioimmunoassay of melanocytes-stimulating hormone (beta-MSH) in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356546"}
{"pmid": "4356549", "title": "Catecholamine uptake processes.", "content": "Catecholamine uptake processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356549"}
{"pmid": "4356548", "title": "Catecholamines in invertebrates.", "content": "Catecholamines in invertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356548"}
{"pmid": "4356550", "title": "Prostaglandins at adrenergic nerve-endings.", "content": "Prostaglandins at adrenergic nerve-endings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356550"}
{"pmid": "4356551", "title": "The mechanisms of action of some antihypertensive drugs.", "content": "The mechanisms of action of some antihypertensive drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356551"}
{"pmid": "4356552", "title": "Dopamine in the basal ganglia. Its role and therapeutic implications (including the clinical use of L-DOPA).", "content": "Dopamine in the basal ganglia. Its role and therapeutic implications (including the clinical use of L-DOPA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356552"}
{"pmid": "4356554", "title": "An efficient ultrafiltration method for enterovirus recovery from ground beef.", "content": "An efficient ultrafiltration method for enterovirus recovery from ground beef.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356554"}
{"pmid": "4356553", "title": "Editorial: Spread of colds.", "content": "Editorial: Spread of colds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356553"}
{"pmid": "4356555", "title": "Purification of Clostridium perfringens type C theta toxin.", "content": "Purification of Clostridium perfringens type C theta toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356555"}
{"pmid": "4356556", "title": "Biosynthesis of thiamine by Phycomyces blakesleeanus.", "content": "Biosynthesis of thiamine by Phycomyces blakesleeanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356556"}
{"pmid": "4356557", "title": "Electron microscopic studies on the trabecular meshwork in two cases of corticosteroid-glaucoma.", "content": "Electron microscopic studies on the trabecular meshwork in two cases of corticosteroid-glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356557"}
{"pmid": "4356558", "title": "Tumour-associated antigen in the serum of rats with large Rous sarcoma virus-induced tumours.", "content": "Tumour-associated antigen in the serum of rats with large Rous sarcoma virus-induced tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356558"}
{"pmid": "4356559", "title": "Growth in spinner culture of AKR mouse cells, the K3b, induced by the Schmidt-Ruppin strain of Rous sarcoma virus.", "content": "Growth in spinner culture of AKR mouse cells, the K3b, induced by the Schmidt-Ruppin strain of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356559"}
{"pmid": "4356560", "title": "Failure of Bacillus Calmette-Guérin (BCG) infection to suppress the growth of transplanted mouse and rat sarcomas.", "content": "Failure of Bacillus Calmette-Guérin (BCG) infection to suppress the growth of transplanted mouse and rat sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356560"}
{"pmid": "4356562", "title": "Time relationship between the lateral geniculate nucleus activity and eye movement in the unanesthetized and reserpinized cat.", "content": "Time relationship between the lateral geniculate nucleus activity and eye movement in the unanesthetized and reserpinized cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356562"}
{"pmid": "4356561", "title": "Effects of L-DOPA on natural night sleep and on rebound of REM sleep.", "content": "Effects of L-DOPA on natural night sleep and on rebound of REM sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356561"}
{"pmid": "4356564", "title": "Presence of fast moving type IV hexokinase isozyme in Morris hepatoma.", "content": "Presence of fast moving type IV hexokinase isozyme in Morris hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356564"}
{"pmid": "4356563", "title": "Synergistic effect of fusidic acid with polymyxin-B and amphotericin-B on transformed and normal fibroblastic cells.", "content": "Synergistic effect of fusidic acid with polymyxin-B and amphotericin-B on transformed and normal fibroblastic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356563"}
{"pmid": "4356565", "title": "Measurement of estrogen-binding capacity in the hormone-dependent and  -independent rat mammary tumors.", "content": "Measurement of estrogen-binding capacity in the hormone-dependent and  -independent rat mammary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356565"}
{"pmid": "4356566", "title": "Carcinostatic effect of 1,1'-polymethylenebis-(1-nitrosourea) on AH-13 and L-1210 cells.", "content": "Carcinostatic effect of 1,1'-polymethylenebis-(1-nitrosourea) on AH-13 and L-1210 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356566"}
{"pmid": "4356567", "title": "A serological survey of adenovirus infection in Pondicherry.", "content": "A serological survey of adenovirus infection in Pondicherry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356567"}
{"pmid": "4356569", "title": "Subplasmalemmal microfilaments and microtubules in resting and phagocytizing cultivated macrophages.", "content": "Subplasmalemmal microfilaments and microtubules in resting and phagocytizing cultivated macrophages. The subplasmalemmal organization of the free and glass-attached surfaces of resting and phagocytizing cultivated macrophages were examined in an attempt to define specific membrane-associated structures related to phagocytosis. From analysis of serial thin sections of oriented cells it was found that the subplasmalemmal region of the attached cell surface has a complex microfilament and microtubule organization relative to the subplasmalemmal area of the free surface. A filamentous network composed of 40-50-A microfilaments extended for a depth of 400-600 A from the attached plasma membrane. Immediately subjacent to the filamentous network was a zone of oriented bundles of 40-50-A microfilaments and a zone of microtubules. Additional microtubules were found to extend from the plasma membrane to the interior of the cell in close association with electron-dense, channellike structures. In contrast, the free aspect of the cultivated macrophage contained only the subplasmalemmal filamentous network. However, after a phagocytic pulse with polystyrene particles (14 microm diam) microtubules and oriented filaments similar to those found on the attached surface were observed surrounding the ingested particles. The observations reported in this paper provide support for the hypothesis that microfilaments and/or microtubules play a role in the translocation of plasma membrane required for the functionally similar processes of phagocytosis and cell attachment to glass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356569"}
{"pmid": "4356568", "title": "The polymerization of actin: its role in the generation of the acrosomal process of certain echinoderm sperm.", "content": "The polymerization of actin: its role in the generation of the acrosomal process of certain echinoderm sperm. When Asterias or Thyone sperm come in contact with egg jelly, a long process which in Thyone measures up to 90 microm in length is formed from the acrosomal region. This process can be generated in less than 30 s. Within this process is a bundle of microfilaments. Water extracts prepared from acetone powders of Asterias sperm contain a protein which binds rabbit skeletal muscle myosin forming a complex whose viscosity is reduced by ATP. Within this extract is a protein with the same molecular weight as muscle actin. It can be purified either by collecting the pellet produced after the addition of Mg(++) or by reextracting an acetone powder of actomyosin prepared by the addition of highly purified muscle myosin to the extract. The sperm actin can be polymerized and by electron microscopy the polymer is indistinguishable from muscle F-actin. The sperm actin was shown to be localized in the microfilaments in the acrosomal processes by: (a) heavy meromyosin binding in situ, (b) sodium dodecyl sulfate (SDS) gel electrophoresis of the isolated acrosomal processes and a comparison to gels of flagella which contain no band corresponding to the molecular weight of actin, and (c) SDS gel electrophoresis of the extract from isolated acrosomal caps. Since the precursor for the microfilaments in the unreacted sperm appears amorphous, we suspected that the force for the generation of the acrosomal process is brought about by the polymerization of the sperm actin. This supposition was confirmed, for when unreacted sperm were lysed with the detergent Triton X-100 and the state of the actin in the sperm extract was analyzed by centrifugation, we determined that at least 80% of the actin in the unreacted sperm was in the monomeric state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356568"}
{"pmid": "4356570", "title": "Microfilaments in the polar lobe constriction of fertilized eggs of Ilyanassa obsoleta.", "content": "Microfilaments in the polar lobe constriction of fertilized eggs of Ilyanassa obsoleta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356570"}
{"pmid": "4356571", "title": "Golgi fractions prepared from rat liver homogenates. I. Isolation procedure and morphological characterization.", "content": "Golgi fractions prepared from rat liver homogenates. I. Isolation procedure and morphological characterization. In devising a new procedure for the isolation of Golgi fractions from rat liver homogenates, we have taken advantage of the overloading with very low density lipoprotein (VLDL) particles that occurs in the Golgi elements of hepatocytes approximately 90 min after ethanol is administered (0.6 g/100 g body weight) by stomach tube to the animals. The VLDLs act as morphological markers as well as density modifiers of these elements. The starting preparation is a total microsomal fraction prepared from liver homogenized (1:5) in 0.25 M sucrose. This fraction is resuspended in 1.15 M sucrose and loaded at the bottom of a discontinuous sucrose density gradient. Centrifugation at approximately 13 x 10(6)g.min yields by flotation three Golgi fractions of density >1.041 and <1.173. The light and intermediate fractions consist essentially of VLDL-loaded Golgi vacuoles and cisternae. Nearly empty, often collapsed, Golgi cisternae are the main component of the heavy fraction. A procedure which subjects the Golgi fractions to hypotonic shock and shearing in a French press at pH 8.5 allows the extraction of the content of the Golgi elements and the subsequent isolation of their membranes by differential centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356571"}
{"pmid": "4356574", "title": "The isolation of enteroviruses from cases of acute conjunctivitis.", "content": "The isolation of enteroviruses from cases of acute conjunctivitis. In two epidemics of acute enterovirus conjunctivitis the diagnosis could only be established by the use of human embryonic organ cultures. In one instance cultures of ciliated respiratory epithelium proved sensitive to the virus but similar culture failed to support growth of the virus from the second outbreak which was isolated in organ cultures of conjunctiva. The virus associated with a third outbreak had previously been isolated from the original material by culture in human embryo kidney cells, but it required passage in organ culture for its detection after the specimens had been diluted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356574"}
{"pmid": "4356573", "title": "New membrane formation during cytokinesis in normal and cytochalasin B-treated eggs of Xenopus laevis. I. Electron microscope observations.", "content": "New membrane formation during cytokinesis in normal and cytochalasin B-treated eggs of Xenopus laevis. I. Electron microscope observations. A method is described for measuring and calculating the preexisting surface in uncleaved Xenopus eggs and the rate of surface growth in cleaving eggs. Surface-marking experiments with cytochalasin B-treated eggs show that the unpigmented surface grows by de novo formation and not by expansion of preexisting pigmented surface. The onset of new surface formation during first cleavage was studied by using transmission electron microscope and scanning electron microscope techniques. At 3-4 min and at 7-8 min after the onset of cleavage the eggs were fixed in the presence of ruthenium red (RR). Evidence is presented that unpigmented surface representing new membrane comes into appearance between four and eight min. This surface has a selective binding capacity for RR. Concomitantly with the appearance of new membrane, endoplasmic reticulum (ER) cisternae are in continuity with, and dense cytoplasmic inclusions coalesce with, the membrane along the furrow. The latter give rise to liposome-like bodies. The possibility is discussed that the ER cisternae transport a surface exudate (a carbohydrate complex), that the dense cytoplasmic inclusions represent pools of membrane precursor, and that membranogenesis takes place by direct insertion of pooled precursors into the cell surface. In a second paper, these findings will be correlated with electrophysiological measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356573"}
{"pmid": "4356575", "title": "Binding of spin-labeled local anesthetics to lobster nerves.", "content": "Binding of spin-labeled local anesthetics to lobster nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356575"}
{"pmid": "4356572", "title": "Golgi fractions prepared from rat liver homogenates. II. Biochemical characterization.", "content": "Golgi fractions prepared from rat liver homogenates. II. Biochemical characterization. The three Golgi fractions isolated from rat liver homogenates by the procedure given in the companion paper account for 6-7% of the protein of the total microsomal fraction used as starting preparation. The lightest, most homogeneous Golgi fraction (GF(1)) lacks typical \"microsomal\" activities, e.g., glucose-6-phosphatase, NADPH-cytochrome c-reductase, and cytochrome P-450. The heaviest, most heterogeneous fraction (GF(3)) is contaminated by endoplasmic reticulum membranes to the extent of approximately 15% of its protein. The three fractions taken together account for nearly all the UDP-galactose: N-acetyl-glucosamine galactosyltransferase of the parent microsomal fraction, and for approximately 70% of the activity of the original homogenate. Omission of the ethanol treatment of the animals reduces the recovery by half. The transferase activity is associated with the membranes of the Golgi elements, not with their content. Galactose is transferred not only to N-acetyl-glucosamine but also to an unidentified lipid-soluble component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356572"}
{"pmid": "4356577", "title": "Acute submonary oil embolism and lethal dose study of an oily contrast medium following portal vein administration into dogs.", "content": "Acute submonary oil embolism and lethal dose study of an oily contrast medium following portal vein administration into dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356577"}
{"pmid": "4356576", "title": "A study of the ultrastructural organization of cytochrome c-phospholipid membranes as revealed by various experimental treatments.", "content": "A study of the ultrastructural organization of cytochrome c-phospholipid membranes as revealed by various experimental treatments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356576"}
{"pmid": "4356578", "title": "Release of acetylcholine from perfused cerebral ventricles in unanaesthetized dogs during waking and sleep.", "content": "Release of acetylcholine from perfused cerebral ventricles in unanaesthetized dogs during waking and sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356578"}
{"pmid": "4356579", "title": "Chemico-biological relationships of follicle stimulating hormone-releasing hormone and luteinizing hormone-releasing hormone.", "content": "Chemico-biological relationships of follicle stimulating hormone-releasing hormone and luteinizing hormone-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356579"}
{"pmid": "4356581", "title": "Gel filtration and preparative free isoelectric focusing of rabbit serum phosphorylphosphatase.", "content": "Gel filtration and preparative free isoelectric focusing of rabbit serum phosphorylphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356581"}
{"pmid": "4356580", "title": "Adenosine 3',5' cyclic monophosphate in Euglena gracilis.", "content": "Adenosine 3',5' cyclic monophosphate in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356580"}
{"pmid": "4356585", "title": "Growth and development in adolescence.", "content": "Growth and development in adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356585"}
{"pmid": "4356584", "title": "Effect of oxidation on chemical spectral and immunochemical properties of egg yolk lipoprotein.", "content": "Effect of oxidation on chemical spectral and immunochemical properties of egg yolk lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356584"}
{"pmid": "4356588", "title": "The molecular and ionic basis of altered myocardial contractility.", "content": "The molecular and ionic basis of altered myocardial contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356588"}
{"pmid": "4356587", "title": "Developing a multiphasic rehabilitation program for psychotic patients in a community mental health clinic.", "content": "Developing a multiphasic rehabilitation program for psychotic patients in a community mental health clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356587"}
{"pmid": "4356589", "title": "Biliary lipid composition in normalipidemic and prebeta hyperlipoproteinemic gallstone patients. Influence of sucrose feeding of the patients on the biliary lipid composition.", "content": "Biliary lipid composition in normalipidemic and prebeta hyperlipoproteinemic gallstone patients. Influence of sucrose feeding of the patients on the biliary lipid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356589"}
{"pmid": "4356597", "title": "Effect of tricyclic antidepressants on phosphodiesterase. Correlation between aggregability and thrombocyte metabolism.", "content": "Effect of tricyclic antidepressants on phosphodiesterase. Correlation between aggregability and thrombocyte metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356597"}
{"pmid": "4356598", "title": "The effect of 10 days' pyrithioxine administration on sleep cycles in rats.", "content": "The effect of 10 days' pyrithioxine administration on sleep cycles in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356598"}
{"pmid": "4356596", "title": "The effect of psychotropic drugs on phosphodiesterase cAMP, ATPase and on 5'nucleotidase.", "content": "The effect of psychotropic drugs on phosphodiesterase cAMP, ATPase and on 5'nucleotidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356596"}
{"pmid": "4356600", "title": "Adenofibrosis in the rat liver, with persistence of polychlorinated biphenyls in adipose tissue.", "content": "Adenofibrosis in the rat liver, with persistence of polychlorinated biphenyls in adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356600"}
{"pmid": "4356601", "title": "Histiocytosis X histogenetic arguments for a Langerhans cell origin.", "content": "Histiocytosis X histogenetic arguments for a Langerhans cell origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356601"}
{"pmid": "4356602", "title": "Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis.", "content": "Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356602"}
{"pmid": "4356603", "title": "Proceedings: phosphate compounds as bone-scanning agents.", "content": "Proceedings: phosphate compounds as bone-scanning agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356603"}
{"pmid": "4356604", "title": "Proceedings: the influence of transplantable tumours on the healing of colonic anastomoses in the rat.", "content": "Proceedings: the influence of transplantable tumours on the healing of colonic anastomoses in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356604"}
{"pmid": "4356605", "title": "Proceedings: controlled trial of wound spraying with poly-antibiotic or povidone iodine aerosols.", "content": "Proceedings: controlled trial of wound spraying with poly-antibiotic or povidone iodine aerosols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356605"}
{"pmid": "4356606", "title": "Transfer factor induced delayed hypersensitivity in X-linked combined immunodeficiency.", "content": "Transfer factor induced delayed hypersensitivity in X-linked combined immunodeficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356606"}
{"pmid": "4356607", "title": "Prostaglandins and the kidney.", "content": "Prostaglandins and the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356607"}
{"pmid": "4356608", "title": "Mechanism of renal handling of angiotensin II in the dog.", "content": "Mechanism of renal handling of angiotensin II in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356608"}
{"pmid": "4356609", "title": "Altered ion transport in vascular smooth muscle from spontaneously hypertensive rats. Influences of aldosterone, norepinephrine, and angiotensin.", "content": "Altered ion transport in vascular smooth muscle from spontaneously hypertensive rats. Influences of aldosterone, norepinephrine, and angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356609"}
{"pmid": "4356610", "title": "Hypertrophy of the ACTH-producing cell following adrenalectomy: a quantitative electron microscopic study.", "content": "Hypertrophy of the ACTH-producing cell following adrenalectomy: a quantitative electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356610"}
{"pmid": "4356611", "title": "ACTH and cAMP stimulation of adrenal ribosomal protein phosphorylation.", "content": "ACTH and cAMP stimulation of adrenal ribosomal protein phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356611"}
{"pmid": "4356612", "title": "Cardiac glucocorticoid receptors: the binding of tritiated dexamethasone in rat and dog heart.", "content": "Cardiac glucocorticoid receptors: the binding of tritiated dexamethasone in rat and dog heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356612"}
{"pmid": "4356613", "title": "Evidence for separate sites of action for the antilipolytic effects of insulin and prostaglandin E1.", "content": "Evidence for separate sites of action for the antilipolytic effects of insulin and prostaglandin E1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356613"}
{"pmid": "4356614", "title": "Analytical and confirmative techniques for dibenzo-p-dioxins based upon their cation radicals.", "content": "Analytical and confirmative techniques for dibenzo-p-dioxins based upon their cation radicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356614"}
{"pmid": "4356615", "title": "Identification of herpes simplex and vaccinia viruses in corneal cell cultures with immunoperoxidase: a light and electron microscopic study.", "content": "Identification of herpes simplex and vaccinia viruses in corneal cell cultures with immunoperoxidase: a light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356615"}
{"pmid": "4356616", "title": "Kinetics of phosphate incorporation into adenosine triphosphate and guanosine triphosphate in bacteria.", "content": "Kinetics of phosphate incorporation into adenosine triphosphate and guanosine triphosphate in bacteria. Escherichia coli cells were labeled with (33)PO(4) for several generations and then (32)PO(4) was added, samples were taken at various times, and adenosine triphosphate (ATP) and guanosine triphosphate (GTP) were purified from an acid extract. The ratio of (32)P/(33)P in each of the six phosphate species was determined and compared to the ratio expected at isotopic steady state. The rate constants of the simplest network of pools which could explain the data, and were consistent with metabolic pathways, were then calculated. In the range of times studied (30 to 3,000 s at 21.5 C) the following generalizations can be made. (i) The gamma-phosphate at ATP requires 2,200 s to achieve 50% of its final specific activity and behaves as if it were exchanging with another species 4.4 times as large, with this other species turning over in 540 s. (ii) The beta-phosphate of ATP and the gamma-phosphate of GTP are in equilibrium with the gamma-phosphate of ATP. (iii) The specific activity of the gamma-phosphate of GTP lags 66 s behind the gamma-phosphate of ATP. (iv) The alpha-phosphates of ATP and GTP have equal specific activities which lag far behind the other four phosphates. A single precursor pool with a turnover time of 416s fits the data best, although a fair fit can be obtained assuming several sequential precursor pools with much shorter turnover times. These findings are consistent with known biosynthetic pathways and the probable flows through them, including the relationship of nucleotide biosynthesis to ribonucleic acid synthesis and turnover.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356616"}
{"pmid": "4356617", "title": "Action of ribonuclease T1 on 30S ribosomes of Escherichia coli and its role in sequence studies on 16S ribonucleic acid.", "content": "Action of ribonuclease T1 on 30S ribosomes of Escherichia coli and its role in sequence studies on 16S ribonucleic acid. Two large ribonucleic acid (RNA) fragments have been obtained from T1-RNase-treated 30S ribosomes of Escherichia coli. One fragment, about 475 nucleotides long, contains all the unique oligonucleotides found by Fellner and associates in sections of 16S RNA designated P, E, E', and K, and one-half the large oligonucleotides of section A. The other large fragment is about 300 nucleotides long and contains the oligonucleotides found in sections C, C', C''. The isolation of these large fragments seems to confirm the arrangement of sections within 16S RNA. There are also recovered from nuclease-treated ribosomes three small fragments, one (120 nucleotides long) from the 5' end, one (26 nucleotides long) from the 3' OH end of the chain, and another section (66 nucleotides long) from the middle of the 16S RNA chain. Small molecular weight material is also generated by nuclease treatment, and about half this material is derived from a region close to the 3' OH end of the 16S RNA chain. This indicates that the most accessible part of the rRNA of E. coli 30S ribosomes is a region 100 to 150 nucleotides long near the 3' end of the chain. A general scheme is proposed to explain the generation of the various-sized RNA products from the rRNA of the 30S ribosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356617"}
{"pmid": "4356619", "title": "The appearance of transient species of cytochrome c upon rapid oxidation or reduction at alkaline pH.", "content": "The appearance of transient species of cytochrome c upon rapid oxidation or reduction at alkaline pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356619"}
{"pmid": "4356618", "title": "Studies on isopentenyl pyrophosphate isomerase with artificial substrates.", "content": "Studies on isopentenyl pyrophosphate isomerase with artificial substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356618"}
{"pmid": "4356620", "title": "Properties of modified cytochromes. II. Ligand binding to reduced carboxymethyl cytochrome c.", "content": "Properties of modified cytochromes. II. Ligand binding to reduced carboxymethyl cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356620"}
{"pmid": "4356621", "title": "The substrate and anomeric specificity of fructokinase.", "content": "The substrate and anomeric specificity of fructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356621"}
{"pmid": "4356622", "title": "Modification of sialyl residues of sialoglycoprotein(s) of the human erythrocyte surface.", "content": "Modification of sialyl residues of sialoglycoprotein(s) of the human erythrocyte surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356622"}
{"pmid": "4356623", "title": "Lecithin: cholesterol acyltransferase of human plasma. Role of chylomicrons, very low, and high density lipoproteins in the reaction.", "content": "Lecithin: cholesterol acyltransferase of human plasma. Role of chylomicrons, very low, and high density lipoproteins in the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356623"}
{"pmid": "4356624", "title": "Mitochondrial functions in an ethanol-induced fatty liver.", "content": "Mitochondrial functions in an ethanol-induced fatty liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356624"}
{"pmid": "4356626", "title": "The cryosurgical treatment of glomus jugulare tumours.", "content": "The cryosurgical treatment of glomus jugulare tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356626"}
{"pmid": "4356628", "title": "Internal maxillary artery ligation for the removal of juvenile nasopharyngeal angiofibroma.", "content": "Internal maxillary artery ligation for the removal of juvenile nasopharyngeal angiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356628"}
{"pmid": "4356627", "title": "Invasive pleomorphic adenoma of hard palate.", "content": "Invasive pleomorphic adenoma of hard palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356627"}
{"pmid": "4356629", "title": "Effects of early postnatal dietary protein restriction and repletion on porcine muscle growth and composition.", "content": "Effects of early postnatal dietary protein restriction and repletion on porcine muscle growth and composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356629"}
{"pmid": "4356625", "title": "Regulation of endogenous phosphorylation of specific proteins in synaptic membrane fractions from rat brain by adenosine 3':5'-monophosphate.", "content": "Regulation of endogenous phosphorylation of specific proteins in synaptic membrane fractions from rat brain by adenosine 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356625"}
{"pmid": "4356630", "title": "Lead-induced inclusion bodies. Solubility, amino acid content, and relationship to residual acidic nuclear proteins.", "content": "Lead-induced inclusion bodies. Solubility, amino acid content, and relationship to residual acidic nuclear proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356630"}
{"pmid": "4356631", "title": "Ultrastructure of sulfatide storage in normal and sulfatase-deficient fibroblasts in vitro.", "content": "Ultrastructure of sulfatide storage in normal and sulfatase-deficient fibroblasts in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356631"}
{"pmid": "4356632", "title": "Effect of phenobarbital and 3-methylcholanthrene pretreatment on the hepatotoxicity of 1,1,1-trichloroethane and 1,1,2-trichloroethane.", "content": "Effect of phenobarbital and 3-methylcholanthrene pretreatment on the hepatotoxicity of 1,1,1-trichloroethane and 1,1,2-trichloroethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356632"}
{"pmid": "4356633", "title": "Tracheal soft tissue mass. Case reports.", "content": "Tracheal soft tissue mass. Case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356633"}
{"pmid": "4356634", "title": "Prevalence of oropharyngeal excreters of leukocyte-transforming agents among a human population.", "content": "Prevalence of oropharyngeal excreters of leukocyte-transforming agents among a human population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356634"}
{"pmid": "4356636", "title": "Acid-base balance of cisternal and lumbar cerebrospinal fluid in hospital patients.", "content": "Acid-base balance of cisternal and lumbar cerebrospinal fluid in hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356636"}
{"pmid": "4356635", "title": "Epidemic keratoconjunctivitis. A severe industrial outbreak due to adenovirus type 8.", "content": "Epidemic keratoconjunctivitis. A severe industrial outbreak due to adenovirus type 8.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356635"}
{"pmid": "4356638", "title": "Editorial: Epidemic keratoconjunctivitis and hand washing.", "content": "Editorial: Epidemic keratoconjunctivitis and hand washing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356638"}
{"pmid": "4356637", "title": "Persistence of poliovirus neutralizing antibodies eight years after immunization with live, attenuated-virus vaccine.", "content": "Persistence of poliovirus neutralizing antibodies eight years after immunization with live, attenuated-virus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356637"}
{"pmid": "4356639", "title": "Editorial: Treatment of oat-celled carcinoma of the bronchus.", "content": "Editorial: Treatment of oat-celled carcinoma of the bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356639"}
{"pmid": "4356641", "title": "Pituitary-gonadal relations in female children and adolescents.", "content": "Pituitary-gonadal relations in female children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356641"}
{"pmid": "4356642", "title": "Response to 2-deoxy-D-glucose and to glucagon in \"ketotic hypoglycemia\" of childhood: evidence for epinephrine deficiency and altered alanine availability.", "content": "Response to 2-deoxy-D-glucose and to glucagon in \"ketotic hypoglycemia\" of childhood: evidence for epinephrine deficiency and altered alanine availability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356642"}
{"pmid": "4356643", "title": "Intestinal mucosa of dogs with ileocystoplasties. Long-term histologic and histochemical changes.", "content": "Intestinal mucosa of dogs with ileocystoplasties. Long-term histologic and histochemical changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356643"}
{"pmid": "4356644", "title": "The metabolism of benomyl fungicide in mammals.", "content": "The metabolism of benomyl fungicide in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356644"}
{"pmid": "4356646", "title": "Recurrent control from motor axon collaterals of Ia inhibitory pathways in the spinal cord of the cat.", "content": "Recurrent control from motor axon collaterals of Ia inhibitory pathways in the spinal cord of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356646"}
{"pmid": "4356645", "title": "Carcinoma of the rectum in old age.", "content": "Carcinoma of the rectum in old age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356645"}
{"pmid": "4356648", "title": "Synthesis of isotopically labeled delta2-isopentenylpyrophosphate.", "content": "Synthesis of isotopically labeled delta2-isopentenylpyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356648"}
{"pmid": "4356647", "title": "Isolation of rat liver plasma membranes by zonal centrifugation: increased yield with Ca2+.", "content": "Isolation of rat liver plasma membranes by zonal centrifugation: increased yield with Ca2+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356647"}
{"pmid": "4356649", "title": "Separation of cyclic 3',5'-AMP from ATP, ADP, and 5'-AMP by precipitation with inorganic compounds.", "content": "Separation of cyclic 3',5'-AMP from ATP, ADP, and 5'-AMP by precipitation with inorganic compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356649"}
{"pmid": "4356650", "title": "A specific micromethod for determination of acetyl residues in proteins.", "content": "A specific micromethod for determination of acetyl residues in proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356650"}
{"pmid": "4356651", "title": "The temperature dependence of the spectroscopic properties of reduced nicotinamide adenine dinucleotide.", "content": "The temperature dependence of the spectroscopic properties of reduced nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356651"}
{"pmid": "4356652", "title": "A quick and specific assay for hydroxyproline.", "content": "A quick and specific assay for hydroxyproline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356652"}
{"pmid": "4356653", "title": "Quantitative determination of reducing sugars, oligosaccharides, and glycoproteins with (3H)borohydride.", "content": "Quantitative determination of reducing sugars, oligosaccharides, and glycoproteins with (3H)borohydride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356653"}
{"pmid": "4356656", "title": "Isotopic evidence for futile cycles in liver cells.", "content": "Isotopic evidence for futile cycles in liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356656"}
{"pmid": "4356657", "title": "Relationship between isotopic reversibility and futile cycles in isolated rat liver parenchymal cells.", "content": "Relationship between isotopic reversibility and futile cycles in isolated rat liver parenchymal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356657"}
{"pmid": "4356658", "title": "Glycogen phosphorylase kinase deficiency: a survey of enzymes in phosphorylase activating system.", "content": "Glycogen phosphorylase kinase deficiency: a survey of enzymes in phosphorylase activating system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356658"}
{"pmid": "4356659", "title": "On the role of a cuprous ion intermediate in the galactose oxidase reaction.", "content": "On the role of a cuprous ion intermediate in the galactose oxidase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356659"}
{"pmid": "4356660", "title": "Development of the cardiac beta adrenergic receptor in fetal rat heart.", "content": "Development of the cardiac beta adrenergic receptor in fetal rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356660"}
{"pmid": "4356661", "title": "The stereospecificity of hydrogen abstraction by uridine diphosphoglucose dehydrogenase.", "content": "The stereospecificity of hydrogen abstraction by uridine diphosphoglucose dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356661"}
{"pmid": "4356662", "title": "Subcellular distribution of methylmalonyl CoA carbonylmutase in human liver extracts.", "content": "Subcellular distribution of methylmalonyl CoA carbonylmutase in human liver extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356662"}
{"pmid": "4356663", "title": "The purification and assay of the prostatic antibacterial factor (PAF).", "content": "The purification and assay of the prostatic antibacterial factor (PAF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356663"}
{"pmid": "4356664", "title": "Energy metabolism in washed human platelets responsive to ADP: comparison with platelets in plasma.", "content": "Energy metabolism in washed human platelets responsive to ADP: comparison with platelets in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356664"}
{"pmid": "4356665", "title": "Effect of repeated treatment of rabbit platelets with low concentrations of thrombin on their function, metabolism and survival.", "content": "Effect of repeated treatment of rabbit platelets with low concentrations of thrombin on their function, metabolism and survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356665"}
{"pmid": "4356666", "title": "Renal vascular resistance and aortic pressure as determinants of sodium reabsorption.", "content": "Renal vascular resistance and aortic pressure as determinants of sodium reabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356666"}
{"pmid": "4356667", "title": "Application of drug-receptor theories to angiotensin.", "content": "Application of drug-receptor theories to angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356667"}
{"pmid": "4356669", "title": "Increased renin activity after cold storage of human plasma.", "content": "Increased renin activity after cold storage of human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356669"}
{"pmid": "4356668", "title": "Cytochrome oxidase of skeletal muscle: adaptive response to chronic disuse.", "content": "Cytochrome oxidase of skeletal muscle: adaptive response to chronic disuse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356668"}
{"pmid": "4356670", "title": "Effects of anions on frog ventricle.", "content": "Effects of anions on frog ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356670"}
{"pmid": "4356671", "title": "The effects of thyroxine and isopropylnoradrenaline on cytochrome oxidase activity in brown adipose tissue.", "content": "The effects of thyroxine and isopropylnoradrenaline on cytochrome oxidase activity in brown adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356671"}
{"pmid": "4356673", "title": "Effects of ACTH on melanophores and iridophores isolated from bullfrog tadpoles.", "content": "Effects of ACTH on melanophores and iridophores isolated from bullfrog tadpoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356673"}
{"pmid": "4356675", "title": "Isolation and characterization of revertant cell lines. 3. Isolation of density-revertants of SV40-transformed 3T3 cells using colchicine.", "content": "Isolation and characterization of revertant cell lines. 3. Isolation of density-revertants of SV40-transformed 3T3 cells using colchicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356675"}
{"pmid": "4356674", "title": "The role of macrophages in the cytotoxic killing of tumour cells in vitro. I. Primary immunization of lymphocytes in vitro for target cell killing and the mechanism of lymphocyte-macrophage cooperation.", "content": "The role of macrophages in the cytotoxic killing of tumour cells in vitro. I. Primary immunization of lymphocytes in vitro for target cell killing and the mechanism of lymphocyte-macrophage cooperation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356674"}
{"pmid": "4356676", "title": "Isolation and characterization of revertant cell lines. IV. Direct selection of serum-revertant sublines of SV40-transformed 3T3 mouse cells.", "content": "Isolation and characterization of revertant cell lines. IV. Direct selection of serum-revertant sublines of SV40-transformed 3T3 mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356676"}
{"pmid": "4356677", "title": "pH, serum and Zn++ in the regulation of DNA synthesis in cultures of chick embryo cells.", "content": "pH, serum and Zn++ in the regulation of DNA synthesis in cultures of chick embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356677"}
{"pmid": "4356678", "title": "Uridine uptake and its intracellular phosphorylation during the cell cycle.", "content": "Uridine uptake and its intracellular phosphorylation during the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356678"}
{"pmid": "4356679", "title": "Inhibition of marrow granulocytic colony formation by phytohemagglutinin.", "content": "Inhibition of marrow granulocytic colony formation by phytohemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356679"}
{"pmid": "4356680", "title": "Improved sensitivity in the measurement of estrogen receptor in human breast cancer.", "content": "Improved sensitivity in the measurement of estrogen receptor in human breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356680"}
{"pmid": "4356681", "title": "Persistent infection of mouse cells with Sindbis virus: role of virulence of strains, auto-interfering particles and interferon.", "content": "Persistent infection of mouse cells with Sindbis virus: role of virulence of strains, auto-interfering particles and interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356681"}
{"pmid": "4356682", "title": "Replication of rhinovirus RNA.", "content": "Replication of rhinovirus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356682"}
{"pmid": "4356683", "title": "The effect of ethidium bromide on L cells and encephalomyocarditis virus replication.", "content": "The effect of ethidium bromide on L cells and encephalomyocarditis virus replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356683"}
{"pmid": "4356685", "title": "Circulating interferon in rabbits after administration of human interferon by different routes.", "content": "Circulating interferon in rabbits after administration of human interferon by different routes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356685"}
{"pmid": "4356684", "title": "Effect of various inhibitors on the expression of polyoma virus-induced surface antigen in BHK21 cells.", "content": "Effect of various inhibitors on the expression of polyoma virus-induced surface antigen in BHK21 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356684"}
{"pmid": "4356686", "title": "Effect of interferon on virus production from isolated single cells.", "content": "Effect of interferon on virus production from isolated single cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356686"}
{"pmid": "4356687", "title": "The mechanism of interferon action in single cells: accumulation of intracellular virus.", "content": "The mechanism of interferon action in single cells: accumulation of intracellular virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356687"}
{"pmid": "4356688", "title": "Genetic and structural implications of tryptic peptide analysis of poliovirus structural protein.", "content": "Genetic and structural implications of tryptic peptide analysis of poliovirus structural protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356688"}
{"pmid": "4356689", "title": "Structural proteins of foot-and-mouth disease virus.", "content": "Structural proteins of foot-and-mouth disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356689"}
{"pmid": "4356691", "title": "Growth and antigenic characteristics of subclones of hamster cells transformed by the Schmidt-Ruppin strain of Rous sarcoma virus.", "content": "Growth and antigenic characteristics of subclones of hamster cells transformed by the Schmidt-Ruppin strain of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356691"}
{"pmid": "4356690", "title": "Inactivation of myxoviruses by lymphoid cells.", "content": "Inactivation of myxoviruses by lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356690"}
{"pmid": "4356692", "title": "Adenohypophysis: ultrastructural cytochemistry. A review.", "content": "Adenohypophysis: ultrastructural cytochemistry. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356692"}
{"pmid": "4356693", "title": "Relief of massive splenomegaly after irradiation of liver involved by Wilms' tumor.", "content": "Relief of massive splenomegaly after irradiation of liver involved by Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356693"}
{"pmid": "4356696", "title": "Electron microscopic studies on various types of inclusions found in autopsy cases. II. Spironolactone inclusion body in autopsy cases and its experimental studies on rhesus monkey.", "content": "Electron microscopic studies on various types of inclusions found in autopsy cases. II. Spironolactone inclusion body in autopsy cases and its experimental studies on rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356696"}
{"pmid": "4356697", "title": "Cultures of renal biopsies: outgrowth of vacuolated and multinucleated cells.", "content": "Cultures of renal biopsies: outgrowth of vacuolated and multinucleated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356697"}
{"pmid": "4356698", "title": "Plasma renin activity in segmental hypoplasia of the kidneys with hypertension.", "content": "Plasma renin activity in segmental hypoplasia of the kidneys with hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356698"}
{"pmid": "4356695", "title": "A granular cell myoblastoma on the ventral surface of the tongue: a case report.", "content": "A granular cell myoblastoma on the ventral surface of the tongue: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356695"}
{"pmid": "4356694", "title": "Vitamin C and chronologic versus bone age.", "content": "Vitamin C and chronologic versus bone age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356694"}
{"pmid": "4356708", "title": "Prolongation of allograft survival in mice by inducers of interferon.", "content": "Prolongation of allograft survival in mice by inducers of interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356708"}
{"pmid": "4356709", "title": "Enhancement of the dye-exclusion cytotoxic test by insulin and inhibition by cyclic adenosine 3:5-monophosphate and theophylline.", "content": "Enhancement of the dye-exclusion cytotoxic test by insulin and inhibition by cyclic adenosine 3:5-monophosphate and theophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356709"}
{"pmid": "4356710", "title": "Herpesviruses in renal transplant patients.", "content": "Herpesviruses in renal transplant patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356710"}
{"pmid": "4356711", "title": "Some aspects of food and nutrition in Sierra Leone.", "content": "Some aspects of food and nutrition in Sierra Leone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356711"}
{"pmid": "4356714", "title": "Multisystem involvement in chronic liver disease. Studies on the incidence and pathogenesis.", "content": "Multisystem involvement in chronic liver disease. Studies on the incidence and pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356714"}
{"pmid": "4356715", "title": "Clinical spectrum of infection due to Bacillus species.", "content": "Clinical spectrum of infection due to Bacillus species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356715"}
{"pmid": "4356717", "title": "Electromyographic and mechanical effects of suxamethonium and tubocurarine on twitch, tetanic and post-tetanic responses.", "content": "Electromyographic and mechanical effects of suxamethonium and tubocurarine on twitch, tetanic and post-tetanic responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356717"}
{"pmid": "4356718", "title": "Disseminated perforating granuloma annulare.", "content": "Disseminated perforating granuloma annulare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356718"}
{"pmid": "4356719", "title": "Tissue interrelationships in cutaneous granuloma.", "content": "Tissue interrelationships in cutaneous granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356719"}
{"pmid": "4356720", "title": "Heterologous protein-RNA interactions in bacterial ribosomes.", "content": "Heterologous protein-RNA interactions in bacterial ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356720"}
{"pmid": "4356721", "title": "On the properties of a membrane-associated protein kinase from Chinese hamster ovary cells.", "content": "On the properties of a membrane-associated protein kinase from Chinese hamster ovary cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356721"}
{"pmid": "4356722", "title": "Effect of acetaldehyde on activity of shuttles for the transport of reducing equivalents into the mitochondria.", "content": "Effect of acetaldehyde on activity of shuttles for the transport of reducing equivalents into the mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356722"}
{"pmid": "4356723", "title": "Regulation of cholesterol synthesis in normal and malignant tissue.", "content": "Regulation of cholesterol synthesis in normal and malignant tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356723"}
{"pmid": "4356724", "title": "Gastropod nervous system as a model experimental system in neurobiological research.", "content": "Gastropod nervous system as a model experimental system in neurobiological research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356724"}
{"pmid": "4356727", "title": "The state pharmacy's role in an aftercare program.", "content": "The state pharmacy's role in an aftercare program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356727"}
{"pmid": "4356728", "title": "Giant islet cell tumor of the pancreas with alpha-like granules. An ultrastructural study.", "content": "Giant islet cell tumor of the pancreas with alpha-like granules. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356728"}
{"pmid": "4356729", "title": "Burkitt's lymphoma in an Israeli child.", "content": "Burkitt's lymphoma in an Israeli child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356729"}
{"pmid": "4356730", "title": "Effect of acute neurogenic stress on hypothalamic corticotropin-releasing factor content.", "content": "Effect of acute neurogenic stress on hypothalamic corticotropin-releasing factor content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356730"}
{"pmid": "4356731", "title": "Intracranial reticulum cell sarcoma associated with immunoglobulin A deficiency.", "content": "Intracranial reticulum cell sarcoma associated with immunoglobulin A deficiency. A case is reported of a 46 year old woman who died after a five month illness characterized by focal neurological signs, evidence of meningeal irritation, and the finding of `blast' cells in the CSF. Immunoglobulin A was consistently absent from her serum and secretions. Necropsy showed extensive infiltration by a reticulum-cell sarcoma of the subarachnoid space, with tumour nodules on several cranial nerves and tumour infiltration of the tuber cinereum. The significance of the association between immunoglobulin A deficiency and neoplasia is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356731"}
{"pmid": "4356732", "title": "Absence of nystagmus during REM sleep in a patient with waking nystagmus and oscillopsia.", "content": "Absence of nystagmus during REM sleep in a patient with waking nystagmus and oscillopsia. Polygraphic recording is presented of the sleep pattern in a young male who developed nystagmus and oscillopsia associated with a remittent CNS demyelinating disease. The vestibular nystagmus observed during wakefulness disappeared during all stages of sleep, including rapid eye movement sleep (REM). Since vestibular nystagmus experimentally induced in wakefulness is also absent during all phases of sleep, these findings suggest that during sleep similar suppressive mechanisms are operative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356732"}
{"pmid": "4356734", "title": "Cell culture contaminants.", "content": "Cell culture contaminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356734"}
{"pmid": "4356735", "title": "Basic principles of a method of nucleoli isolation.", "content": "Basic principles of a method of nucleoli isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356735"}
{"pmid": "4356736", "title": "A technique for studying chemotaxis of leukocytes in well-defined chemotactic fields.", "content": "A technique for studying chemotaxis of leukocytes in well-defined chemotactic fields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356736"}
{"pmid": "4356733", "title": "Ectopic pinealoma: an unusual clinical presentation and a histochemical comparison with a seminoma of the testis.", "content": "Ectopic pinealoma: an unusual clinical presentation and a histochemical comparison with a seminoma of the testis. A patient with ectopic pinealoma first presented with apparent anorexia nervosa and hypernatraemic coma. A history of diabetes insipidus two months previously was not known on admission to hospital. The diabetes insipidus was unmasked by the administration of steroids. Neuroendocrinal and neuropathological aspects of the case are discussed with reference to the march of symptoms due to the growth of the tumour. Histochemical evidence is presented supporting the similarity between ectopic pinealoma and seminoma which suggests that they may more properly be referred to as atypical teratomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356733"}
{"pmid": "4356738", "title": "Divergent action mechanism of cAMP and dibutyryl cAMP on cell proliferation and macromolecular synthesis in HeLa S3 cultures.", "content": "Divergent action mechanism of cAMP and dibutyryl cAMP on cell proliferation and macromolecular synthesis in HeLa S3 cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356738"}
{"pmid": "4356739", "title": "The isolation and survival characterization of radiation and chemical-mutagen sensitive mutants of Pseudomonas aeruginosa.", "content": "The isolation and survival characterization of radiation and chemical-mutagen sensitive mutants of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356739"}
{"pmid": "4356741", "title": "Mutagen sensitivity of Drosophila melanogaster. I. Isolation and preliminary characterization of a methyl methanesulphonate-sensitive strain.", "content": "Mutagen sensitivity of Drosophila melanogaster. I. Isolation and preliminary characterization of a methyl methanesulphonate-sensitive strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356741"}
{"pmid": "4356740", "title": "Molecular specificity of 2-aminopurine in Saccharomyces cerevisiae.", "content": "Molecular specificity of 2-aminopurine in Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356740"}
{"pmid": "4356742", "title": "The nature of reverse mutations in Drosophila melanogaster.", "content": "The nature of reverse mutations in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356742"}
{"pmid": "4356743", "title": "Enhancement by caffeine of N-methyl-N-nitrosourea-induced mutations and chromosome aberrations in Chinese hamster cells.", "content": "Enhancement by caffeine of N-methyl-N-nitrosourea-induced mutations and chromosome aberrations in Chinese hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356743"}
{"pmid": "4356744", "title": "Induced discontinuous lesions in the X-chromosome of Drosophila.", "content": "Induced discontinuous lesions in the X-chromosome of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356744"}
{"pmid": "4356745", "title": "DNA repair capacity and susceptibility to chromosome breakage in xeroderma pigmentosum cells.", "content": "DNA repair capacity and susceptibility to chromosome breakage in xeroderma pigmentosum cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356745"}
{"pmid": "4356746", "title": "Absence of Epstein-Barr viral DNA in American Burkitt's lymphoma.", "content": "Absence of Epstein-Barr viral DNA in American Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356746"}
{"pmid": "4356750", "title": "A polyoma-induced hamster tumor cell with altered DNA synthesis in vivo and reduced polynucleotide ligase activity in vitro.", "content": "A polyoma-induced hamster tumor cell with altered DNA synthesis in vivo and reduced polynucleotide ligase activity in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356750"}
{"pmid": "4356753", "title": "Influence of chlorine dioxide water treatment on numbers of bacteria associated with processed turkey.", "content": "Influence of chlorine dioxide water treatment on numbers of bacteria associated with processed turkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356753"}
{"pmid": "4356754", "title": "Relative concentration and plasma content of yolk lipoprotein precursor in three lines of turkeys.", "content": "Relative concentration and plasma content of yolk lipoprotein precursor in three lines of turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356754"}
{"pmid": "4356757", "title": "In vitro studies of human tumor and embryonic tissue.", "content": "In vitro studies of human tumor and embryonic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356757"}
{"pmid": "4356762", "title": "The lysosomal system in lymphocytes--from cyclic AMP to gene activation.", "content": "The lysosomal system in lymphocytes--from cyclic AMP to gene activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356762"}
{"pmid": "4356761", "title": "The effect of LPF (leukocytosis promoting factor) on the kinetics of colony forming cells.", "content": "The effect of LPF (leukocytosis promoting factor) on the kinetics of colony forming cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356761"}
{"pmid": "4356763", "title": "Ultrastructure and cytochemistry of the synapse: isolation and nature of receptors in the central nervous system.", "content": "Ultrastructure and cytochemistry of the synapse: isolation and nature of receptors in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356763"}
{"pmid": "4356764", "title": "The types and sites of cholinergic receptors.", "content": "The types and sites of cholinergic receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356764"}
{"pmid": "4356765", "title": "Effects of drugs on inhibitory synapses.", "content": "Effects of drugs on inhibitory synapses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356765"}
{"pmid": "4356766", "title": "Biochemistry of synaptic plasticity studied in single neurons.", "content": "Biochemistry of synaptic plasticity studied in single neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356766"}
{"pmid": "4356767", "title": "Cyclic adenosine 3',5'-monophosphate and estrogenic stimulation of uterine metabolism.", "content": "Cyclic adenosine 3',5'-monophosphate and estrogenic stimulation of uterine metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356767"}
{"pmid": "4356768", "title": "Aggregation of human blood platelets by unrelated antigen-antibody reaction: sequence of reaction and role of complement.", "content": "Aggregation of human blood platelets by unrelated antigen-antibody reaction: sequence of reaction and role of complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356768"}
{"pmid": "4356760", "title": "Cytologic aspects of abortive transformation in the polyoma virus-hamster cell system.", "content": "Cytologic aspects of abortive transformation in the polyoma virus-hamster cell system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356760"}
{"pmid": "4356769", "title": "Thyroid iodine metabolism in vitro. I. Experimental technique.", "content": "Thyroid iodine metabolism in vitro. I. Experimental technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356769"}
{"pmid": "4356771", "title": "Experimental infection with mouse adenovirus in adult mice.", "content": "Experimental infection with mouse adenovirus in adult mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356771"}
{"pmid": "4356774", "title": "Rapid method for the concentration and partial purification of herpes simplex viruses types 1 and 2. Brief report.", "content": "Rapid method for the concentration and partial purification of herpes simplex viruses types 1 and 2. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356774"}
{"pmid": "4356772", "title": "DNA-dependent DNA polymerase pattern in noninfected and herpesvirus infected rabbit kidney cells.", "content": "DNA-dependent DNA polymerase pattern in noninfected and herpesvirus infected rabbit kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356772"}
{"pmid": "4356775", "title": "Spin label motion in fatty acids.", "content": "Spin label motion in fatty acids. Spin labels dissolved in highly purified fatty acid systems exhibit nearly identical tumbling rates in liquid and solid phases. Even though the spin labels do not have the same molecular geometry as the lipid matrix the melting point of the matrix can be inferred by measurements of the temperature dependency of molecular motion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356775"}
{"pmid": "4356773", "title": "Inhibition of hog cholera virus by acriflavine. A property shared with bovine virus diarrhoea virus. Brief report.", "content": "Inhibition of hog cholera virus by acriflavine. A property shared with bovine virus diarrhoea virus. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356773"}
{"pmid": "4356776", "title": "Preliminary report of results of Harris total hip replacement.", "content": "Preliminary report of results of Harris total hip replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356776"}
{"pmid": "4356777", "title": "Interim results of Charnley-Müller total hip arthroplasty.", "content": "Interim results of Charnley-Müller total hip arthroplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356777"}
{"pmid": "4356778", "title": "Total hip replacement using the \"Brunswik-system\".", "content": "Total hip replacement using the \"Brunswik-system\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356778"}
{"pmid": "4356779", "title": "Evaluation of total hip replacement arthroplasties.", "content": "Evaluation of total hip replacement arthroplasties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356779"}
{"pmid": "4356780", "title": "The Stanmore metal on metal total hip prosthesis using a three pin type cup. A follow-up of 100 arthroplasties over nine years.", "content": "The Stanmore metal on metal total hip prosthesis using a three pin type cup. A follow-up of 100 arthroplasties over nine years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356780"}
{"pmid": "4356781", "title": "Results in patients with total hip replacement arthroplasty.", "content": "Results in patients with total hip replacement arthroplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356781"}
{"pmid": "4356782", "title": "Complications revisited. The debit side of total hip replacement.", "content": "Complications revisited. The debit side of total hip replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356782"}
{"pmid": "4356784", "title": "Structural studies by proton NMR of cytochrome C-557 from Crithidia oncopelti.", "content": "Structural studies by proton NMR of cytochrome C-557 from Crithidia oncopelti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356784"}
{"pmid": "4356785", "title": "Alteration of subcellular organelles induced by compression.", "content": "Alteration of subcellular organelles induced by compression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356785"}
{"pmid": "4356786", "title": "Direct measurement of the midpoint potential of the primary electron acceptor in Rhodopseudomonas spheroides in situ and in the isolated state: some relationships with pH and o-phenanthroline.", "content": "Direct measurement of the midpoint potential of the primary electron acceptor in Rhodopseudomonas spheroides in situ and in the isolated state: some relationships with pH and o-phenanthroline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356786"}
{"pmid": "4356788", "title": "Prostaglandin production by neuroblastoma, glioma and fibroblast cell lines; stimulation by N6,02'-dibutyryl adenosine 3':5'-cyclic monophosphate.", "content": "Prostaglandin production by neuroblastoma, glioma and fibroblast cell lines; stimulation by N6,02'-dibutyryl adenosine 3':5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356788"}
{"pmid": "4356787", "title": "Distinction between oxidizing and reducing sites of cytochrome c by chemical modification with pyridoxal phosphate.", "content": "Distinction between oxidizing and reducing sites of cytochrome c by chemical modification with pyridoxal phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356787"}
{"pmid": "4356789", "title": "Electron spin resonance spectra of feline NO-hemoglobins.", "content": "Electron spin resonance spectra of feline NO-hemoglobins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356789"}
{"pmid": "4356792", "title": "Primary pulmonary scar carcinomas.", "content": "Primary pulmonary scar carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356792"}
{"pmid": "4356791", "title": "Unifying concepts in the response of mammalian cells to stimuli.", "content": "Unifying concepts in the response of mammalian cells to stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356791"}
{"pmid": "4356797", "title": "Cation-exchange properties of dry silicate membranes.", "content": "Cation-exchange properties of dry silicate membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356797"}
{"pmid": "4356798", "title": "Role of cyclic AMP in the control of epidermal cell growth and differentiation.", "content": "Role of cyclic AMP in the control of epidermal cell growth and differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356798"}
{"pmid": "4356800", "title": "Suppression by vitamins D2 and D3 of hamster cheek pouch carcinoma induced with 9,10-dimethyl-1,2-benzanthracene with a discussion of the role of intracellular calcium in the development of tumors.", "content": "Suppression by vitamins D2 and D3 of hamster cheek pouch carcinoma induced with 9,10-dimethyl-1,2-benzanthracene with a discussion of the role of intracellular calcium in the development of tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356800"}
{"pmid": "4356801", "title": "Effect of phenobarbital on MHV-3 viral hepatitis of the mouse.", "content": "Effect of phenobarbital on MHV-3 viral hepatitis of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356801"}
{"pmid": "4356806", "title": "The suprasellar meningioma. A review of the literature and presentation of a series of 31 cases.", "content": "The suprasellar meningioma. A review of the literature and presentation of a series of 31 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356806"}
{"pmid": "4356807", "title": "Genetics and physiology of colour vision (\"my story on colour vision genetics and physiology\").", "content": "Genetics and physiology of colour vision (\"my story on colour vision genetics and physiology\").", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356807"}
{"pmid": "4356808", "title": "Growth hormone and prolactin in unipolar and bipolar depressed patients: responses to hypoglycemia and L-dopa.", "content": "Growth hormone and prolactin in unipolar and bipolar depressed patients: responses to hypoglycemia and L-dopa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356808"}
{"pmid": "4356810", "title": "Pseudomonas corneal ulceration: an electron microscopic study.", "content": "Pseudomonas corneal ulceration: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356810"}
{"pmid": "4356811", "title": "Corneal collagenases: evidence for zinc metalloenzymes.", "content": "Corneal collagenases: evidence for zinc metalloenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356811"}
{"pmid": "4356812", "title": "Palpebral metastasis of mammary carcinoma: an electron microscopic study.", "content": "Palpebral metastasis of mammary carcinoma: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356812"}
{"pmid": "4356796", "title": "The bone scintiphotographic examination with 99Tc-tin-pyrophosphate.", "content": "The bone scintiphotographic examination with 99Tc-tin-pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356796"}
{"pmid": "4356813", "title": "The effect of neuraminidase treatment of ribosome-free membranes on their ribosomal reattachment ability.", "content": "The effect of neuraminidase treatment of ribosome-free membranes on their ribosomal reattachment ability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356813"}
{"pmid": "4356814", "title": "Similarity of the 0.35 M NaCl soluble nuclear proteins and the nonhistone chromosomal proteins.", "content": "Similarity of the 0.35 M NaCl soluble nuclear proteins and the nonhistone chromosomal proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356814"}
{"pmid": "4356815", "title": "Action of the S1 endonuclease from Aspergillus oryzae on simian virus 40 supercoiled component I DNA.", "content": "Action of the S1 endonuclease from Aspergillus oryzae on simian virus 40 supercoiled component I DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356815"}
{"pmid": "4356816", "title": "Active subunits of rabbit liver fructose diphosphatase.", "content": "Active subunits of rabbit liver fructose diphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356816"}
{"pmid": "4356818", "title": "Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol.", "content": "Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356818"}
{"pmid": "4356817", "title": "Subunits of oncornavirus high-molecular-weight RNA. II. Detection of double-stranded-regions in 60S AMV (avian myeloblastosis virus) RNA.", "content": "Subunits of oncornavirus high-molecular-weight RNA. II. Detection of double-stranded-regions in 60S AMV (avian myeloblastosis virus) RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356817"}
{"pmid": "4356819", "title": "Calorimetric investigation of binding of NADH to pig muscle lactate dehydrogenase.", "content": "Calorimetric investigation of binding of NADH to pig muscle lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356819"}
{"pmid": "4356820", "title": "pH induced increase in cyclic GMP reactivity with cyclic AMP-dependent protein kinases.", "content": "pH induced increase in cyclic GMP reactivity with cyclic AMP-dependent protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356820"}
{"pmid": "4356821", "title": "Specificity of reticulocyte initiation factors for the translation of globin messenger RNA.", "content": "Specificity of reticulocyte initiation factors for the translation of globin messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356821"}
{"pmid": "4356822", "title": "Increased capacity for RNA synthesis in Dictyostelium discoideum nuclei induced by exposure to cyclic AMP or 5'-AMP.", "content": "Increased capacity for RNA synthesis in Dictyostelium discoideum nuclei induced by exposure to cyclic AMP or 5'-AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356822"}
{"pmid": "4356823", "title": "Angiotensin binding to rat adrenal capsular cell suspensions.", "content": "Angiotensin binding to rat adrenal capsular cell suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356823"}
{"pmid": "4356825", "title": "Effect of ACTH on biosynthesis of aldosterone and corticosterone by monolayer cultures of rat adrenal zona glomerulosa cells.", "content": "Effect of ACTH on biosynthesis of aldosterone and corticosterone by monolayer cultures of rat adrenal zona glomerulosa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356825"}
{"pmid": "4356824", "title": "Influence of protease inhibitors and energy metabolism on intracellular protein breakdown in starving Escherichia coli.", "content": "Influence of protease inhibitors and energy metabolism on intracellular protein breakdown in starving Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356824"}
{"pmid": "4356826", "title": "Utilization of C20-polyunsaturated fatty acids by a yeast fatty acid desaturase mutant.", "content": "Utilization of C20-polyunsaturated fatty acids by a yeast fatty acid desaturase mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356826"}
{"pmid": "4356827", "title": "Effect of poly(ADP-ribose) formation on DNA synthesis and DNA fragmentation in nuclei of rat liver and rat ascites hepatoma AH-130 cells.", "content": "Effect of poly(ADP-ribose) formation on DNA synthesis and DNA fragmentation in nuclei of rat liver and rat ascites hepatoma AH-130 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356827"}
{"pmid": "4356828", "title": "Unique nucleotide sequence adjacent to the poly (A) region in yeast RNA.", "content": "Unique nucleotide sequence adjacent to the poly (A) region in yeast RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356828"}
{"pmid": "4356829", "title": "A qualitative haemoglobin assessment method.", "content": "A qualitative haemoglobin assessment method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356829"}
{"pmid": "4356832", "title": "DNA-dependent RNA polymerase in germinating bean rust uredospores.", "content": "DNA-dependent RNA polymerase in germinating bean rust uredospores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356832"}
{"pmid": "4356831", "title": "Effect of aldehyde fixatives on the adenosine phosphatases and ultrastructure of Vitreoscilla.", "content": "Effect of aldehyde fixatives on the adenosine phosphatases and ultrastructure of Vitreoscilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356831"}
{"pmid": "4356833", "title": "Tyrosinase from embryonic chick retinal pigment epithelium.", "content": "Tyrosinase from embryonic chick retinal pigment epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356833"}
{"pmid": "4356834", "title": "D-galactosamine hepatotoxicity. 3. Normoactive smooth endoplasmic reticulum and modification by phenobarbital.", "content": "D-galactosamine hepatotoxicity. 3. Normoactive smooth endoplasmic reticulum and modification by phenobarbital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356834"}
{"pmid": "4356835", "title": "Phosphorylation and redox states in ischemic liver.", "content": "Phosphorylation and redox states in ischemic liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356835"}
{"pmid": "4356836", "title": "Differential distribution of angiotensin converting enzyme in the anterior and posterior lobe of the rat pituitary.", "content": "Differential distribution of angiotensin converting enzyme in the anterior and posterior lobe of the rat pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356836"}
{"pmid": "4356837", "title": "Proteins in the degenerative retina of C3H mice: deficiency of a cyclic-nucleotide phosphodiesterase and opsin.", "content": "Proteins in the degenerative retina of C3H mice: deficiency of a cyclic-nucleotide phosphodiesterase and opsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356837"}
{"pmid": "4356839", "title": "Subcellular localization of (14C)adenine derivatives newly-formed in cerebral tissues and the effects of electrical excitation.", "content": "Subcellular localization of (14C)adenine derivatives newly-formed in cerebral tissues and the effects of electrical excitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356839"}
{"pmid": "4356838", "title": "Histamine-dependent formation of N-acetyl-aspartyl peptides in mouse brain.", "content": "Histamine-dependent formation of N-acetyl-aspartyl peptides in mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356838"}
{"pmid": "4356841", "title": "A rapid fluorometric assay for 2',3'-cyclic adenosine monophosphate 3'-phosphoesterhydrolase.", "content": "A rapid fluorometric assay for 2',3'-cyclic adenosine monophosphate 3'-phosphoesterhydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356841"}
{"pmid": "4356840", "title": "Glyceride metabolism in cultured cells dissociated from rat cerebral cortex.", "content": "Glyceride metabolism in cultured cells dissociated from rat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356840"}
{"pmid": "4356842", "title": "Letters: A simple sphingomyelinase determination for Niemann-Pick disease: differential diagnosis of types A, B and C.", "content": "Letters: A simple sphingomyelinase determination for Niemann-Pick disease: differential diagnosis of types A, B and C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356842"}
{"pmid": "4356844", "title": "The electronic structure of and conformational energy barrier to rotation a round the C-N glycosidic linkage in adenosine-3',5'-cyclicmonophosphate (cyclic AMP) and its phosphonate analog.", "content": "The electronic structure of and conformational energy barrier to rotation a round the C-N glycosidic linkage in adenosine-3',5'-cyclicmonophosphate (cyclic AMP) and its phosphonate analog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356844"}
{"pmid": "4356845", "title": "A comparative study of electronic and neural networks involved in pattern recognition.", "content": "A comparative study of electronic and neural networks involved in pattern recognition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356845"}
{"pmid": "4356843", "title": "Matching of facilitation at the neuromuscular junction of the lobster: a possible case for influence of muscle on nerve.", "content": "Matching of facilitation at the neuromuscular junction of the lobster: a possible case for influence of muscle on nerve. 1. The facilitation of neuromuscular transmission, which occurs during repetitive activation, was examined in the proximal accessory flexor muscle in walking legs of the lobster using electrophysiological techniques.2. Post-synaptic potentials (p.s.p.s) in different muscle fibres facilitated to markedly different degrees. P.s.p.s in some fibres did not facilitate at all, while in others they increased in size by 20-30 times during stimulation at 20 Hz even though all the excitatory neuromuscular synapses are made by a single axon.3. Stimulation of widely separated groups of synapses on any single muscle fibre evoked p.s.p.s with closely matched facilitation properties. Extracellular p.s.p.s recorded from single synaptic spots showed the same characteristics of facilitation as those of intracellular p.s.p.s in the same muscle fibre, suggesting that individual synaptic contacts on any single fibre are similar to each other.4. Facilitation can be accounted for by an increase in the number of quanta released from the nerve terminals. There is no evidence for an increase in post-synaptic membrane sensitivity.5. Low Ca solutions reduce transmitter release with comparatively little change in facilitation, while Cs solutions increase the size of p.s.p.s without increasing the amplitude of spontaneous miniature potentials. Thus, at poorly facilitating synapses it is unlikely that the absence of facilitation is caused by the saturation of some post-synaptic process.6. It is concluded that the excitatory presynaptic nerve terminals on a single muscle fibre have matching facilitation characteristics. Some interaction between individual muscle fibres and their associated nerve endings may be required to establish or maintain this matching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356843"}
{"pmid": "4356846", "title": "Hyperlipoproteinemia. Some basic concepts on diagnosis and management.", "content": "Hyperlipoproteinemia. Some basic concepts on diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356846"}
{"pmid": "4356847", "title": "The Coronary Drug Project. Findings leading to discontinuation of the 2.5-mg day estrogen group. The coronary Drug Project Research Group.", "content": "The Coronary Drug Project. Findings leading to discontinuation of the 2.5-mg day estrogen group. The coronary Drug Project Research Group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356847"}
{"pmid": "4356848", "title": "Shock during oral glucose tolerance testing.", "content": "Shock during oral glucose tolerance testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356848"}
{"pmid": "4356849", "title": "Expression of human red cell acid phosphatase activity in placenta and other tissues.", "content": "Expression of human red cell acid phosphatase activity in placenta and other tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356849"}
{"pmid": "4356850", "title": "Properties of human serum factors precipitating bovine enterovirus.", "content": "Properties of human serum factors precipitating bovine enterovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356850"}
{"pmid": "4356853", "title": "Immunoglobulins and measles antibodies in optic neuritis.", "content": "Immunoglobulins and measles antibodies in optic neuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356853"}
{"pmid": "4356854", "title": "Letter: Intranuclear virus-like particles and cytoplasmic HbAg in chronic hepatitis.", "content": "Letter: Intranuclear virus-like particles and cytoplasmic HbAg in chronic hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356854"}
{"pmid": "4356855", "title": "Letter: Viral hemorrhagic cystitis.", "content": "Letter: Viral hemorrhagic cystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356855"}
{"pmid": "4356856", "title": "Tumour specific cell surface antigen and Forssman antigen associated with rat and hamster cells transformed with different strains of avian sarcoma virus.", "content": "Tumour specific cell surface antigen and Forssman antigen associated with rat and hamster cells transformed with different strains of avian sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356856"}
{"pmid": "4356857", "title": "Isolation of C-type RNA-viruses from stable cell cultures of human tumours.", "content": "Isolation of C-type RNA-viruses from stable cell cultures of human tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356857"}
{"pmid": "4356858", "title": "Early production of Rous sarcoma virus in cocultivated virogenic mammalian and chick embryo cells.", "content": "Early production of Rous sarcoma virus in cocultivated virogenic mammalian and chick embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356858"}
{"pmid": "4356859", "title": "Isozyme patterns of hepatomas and tumour progression.", "content": "Isozyme patterns of hepatomas and tumour progression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356859"}
{"pmid": "4356861", "title": "Cell surface alterations in transformed and mitotic normal cells monitored with plant agglutinins.", "content": "Cell surface alterations in transformed and mitotic normal cells monitored with plant agglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356861"}
{"pmid": "4356860", "title": "Ultrastructural organ-specificity and polymorphism of the cancer cells.", "content": "Ultrastructural organ-specificity and polymorphism of the cancer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356860"}
{"pmid": "4356862", "title": "Interactions of normal and neoplastic cells with various surfaces.", "content": "Interactions of normal and neoplastic cells with various surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356862"}
{"pmid": "4356867", "title": "Studies of immunological reactivity following syngeneic or allogeneic marrow grafts in man.", "content": "Studies of immunological reactivity following syngeneic or allogeneic marrow grafts in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356867"}
{"pmid": "4356866", "title": "Hematopoietic colony formation in a macrophage layer provided by intraperitoneal insertion of cellulose acetate membrane.", "content": "Hematopoietic colony formation in a macrophage layer provided by intraperitoneal insertion of cellulose acetate membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356866"}
{"pmid": "4356868", "title": "Liaison nurse: ombudsman for the chronically ill.", "content": "Liaison nurse: ombudsman for the chronically ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356868"}
{"pmid": "4356869", "title": "Extrachromosomal DNA in bacteria.", "content": "Extrachromosomal DNA in bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356869"}
{"pmid": "4356870", "title": "Measles and other virus-specific immunoglobulins in multiple sclerosis.", "content": "Measles and other virus-specific immunoglobulins in multiple sclerosis. Immunoglobulins M and G specific for meales, herpes simplex, and rubella viruses were assayed by the fluorescent antibody method in sera and cerebrospinal fluids (C.S.F.) obtained simultaneously from 30 patients with multiple sclerosis, 30 patients with other neurological diseases, and 30 \"normal\" control subjects. Sera of 11 out of 30 patients with multiple sclerosis had IgM which reacted specifically with measles virus-infected cells, compared with 2 out of 30 of the patients with other neurological diseases and none of the 30 normal controls. Virus-specific IgM was not found in C.S.F. by this method.The geometric mean titre of measles virus-specific IgG in serum was significantly higher in the multiple sclerosis group than in either control group, and while IgG specific for all three viruses was found in C.S.F., suggesting transfer across the blood-brain barrier, measles IgG predominated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356870"}
{"pmid": "4356871", "title": "Letter: Female sterility produced by investigation.", "content": "Letter: Female sterility produced by investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356871"}
{"pmid": "4356872", "title": "Letter: Protection of cytomegalovirus-infected cells by IgG antibody.", "content": "Letter: Protection of cytomegalovirus-infected cells by IgG antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356872"}
{"pmid": "4356874", "title": "Synovioma in a dog.", "content": "Synovioma in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356874"}
{"pmid": "4356873", "title": "Distribution of a polychlorinated terphenyl (PCT) (Aroclor 5460) in rat tissues and effect on hepatic microsomal mixed function oxidases.", "content": "Distribution of a polychlorinated terphenyl (PCT) (Aroclor 5460) in rat tissues and effect on hepatic microsomal mixed function oxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356873"}
{"pmid": "4356875", "title": "Studies on nucleotide analogs. I. Synthesis of two 9-alpha-D-mannofuranosyladenine phosphates, and their inhibition of adenylate kinase.", "content": "Studies on nucleotide analogs. I. Synthesis of two 9-alpha-D-mannofuranosyladenine phosphates, and their inhibition of adenylate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356875"}
{"pmid": "4356878", "title": "The chemical composition of algal cell walls.", "content": "The chemical composition of algal cell walls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356878"}
{"pmid": "4356881", "title": "Cyclic AMP and thyroid hormone synthesis. I. Stimulation of the biosynthesis of thyroglobulin-related polypeptides and proteins in bovine thyroid slices.", "content": "Cyclic AMP and thyroid hormone synthesis. I. Stimulation of the biosynthesis of thyroglobulin-related polypeptides and proteins in bovine thyroid slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356881"}
{"pmid": "4356882", "title": "Editorial: A progress report on lipoprotein phenotyping.", "content": "Editorial: A progress report on lipoprotein phenotyping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356882"}
{"pmid": "4356883", "title": "Effect of epinephrine on platelet lipid metabolism.", "content": "Effect of epinephrine on platelet lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356883"}
{"pmid": "4356884", "title": "Glycerol-induced acute renal failure after acute plasma renin activity suppression.", "content": "Glycerol-induced acute renal failure after acute plasma renin activity suppression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356884"}
{"pmid": "4356885", "title": "Interaction of cultured human fibroblasts with fibrin: modification by drugs and aging in vitro.", "content": "Interaction of cultured human fibroblasts with fibrin: modification by drugs and aging in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356885"}
{"pmid": "4356886", "title": "Phosphatidate phosphatase in human platelets.", "content": "Phosphatidate phosphatase in human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356886"}
{"pmid": "4356887", "title": "Recent advances in canine virus research.", "content": "Recent advances in canine virus research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356887"}
{"pmid": "4356888", "title": "Protection of dogs against canine hepatitis with Toronto A26-61 virus (kennel cough isolate) hexon antigen.", "content": "Protection of dogs against canine hepatitis with Toronto A26-61 virus (kennel cough isolate) hexon antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356888"}
{"pmid": "4356889", "title": "Segmental resection for lung cancer. A fifteen-year experience.", "content": "Segmental resection for lung cancer. A fifteen-year experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356889"}
{"pmid": "4356890", "title": "Acute obstruction of tricuspid valve by Wilms' tumor.", "content": "Acute obstruction of tricuspid valve by Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356890"}
{"pmid": "4356892", "title": "Case for diagnosis. Wilm's tumor.", "content": "Case for diagnosis. Wilm's tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356892"}
{"pmid": "4356893", "title": "Mutagenicity of dichlorvos and methyl methanesulphonate for Escherichia coli WP2 and some derivatives deficient in DNA repair.", "content": "Mutagenicity of dichlorvos and methyl methanesulphonate for Escherichia coli WP2 and some derivatives deficient in DNA repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356893"}
{"pmid": "4356894", "title": "The nature of single-strand breaks in DNA following treatment of L-cells with methylating agents.", "content": "The nature of single-strand breaks in DNA following treatment of L-cells with methylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356894"}
{"pmid": "4356895", "title": "Letter to the editor: Dosimetry of the chemical mutagen Ethylmethanesulfonate.", "content": "Letter to the editor: Dosimetry of the chemical mutagen Ethylmethanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356895"}
{"pmid": "4356896", "title": "Effects of irradiation on the responses of animal cells to virus.", "content": "Effects of irradiation on the responses of animal cells to virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356896"}
{"pmid": "4356897", "title": "Virus diseases associated with cutaneous eruptions.", "content": "Virus diseases associated with cutaneous eruptions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356897"}
{"pmid": "4356898", "title": "Viruses in human carcinogenesis.", "content": "Viruses in human carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356898"}
{"pmid": "4356899", "title": "Differences between extracellular and intracellular forms of poxvirus and their implications.", "content": "Differences between extracellular and intracellular forms of poxvirus and their implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356899"}
{"pmid": "4356902", "title": "Letter: Insulin activity: the solid matrix.", "content": "Letter: Insulin activity: the solid matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356902"}
{"pmid": "4356904", "title": "An electron microscopic study of the neuroglial reaction in the hypoglossal nucleus after transection of the hypoglossal nerve.", "content": "An electron microscopic study of the neuroglial reaction in the hypoglossal nucleus after transection of the hypoglossal nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356904"}
{"pmid": "4356905", "title": "The formation and degradation of granules in eosinophil cells.", "content": "The formation and degradation of granules in eosinophil cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356905"}
{"pmid": "4356906", "title": "Studies on the urophysis and the caudal neurosecretory system in a teleost, Ompok bimaculatus (Bloch).", "content": "Studies on the urophysis and the caudal neurosecretory system in a teleost, Ompok bimaculatus (Bloch).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356906"}
{"pmid": "4356907", "title": "Studies on boar semen. I. A new major defect in the sperm head, the \"SME\"-defect.", "content": "Studies on boar semen. I. A new major defect in the sperm head, the \"SME\"-defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356907"}
{"pmid": "4356908", "title": "Studies on boar semen. II. Abnormal mitochondrial helix \"pseudo-corkscrew sperm\" due to ejaculation in the preputial cavity.", "content": "Studies on boar semen. II. Abnormal mitochondrial helix \"pseudo-corkscrew sperm\" due to ejaculation in the preputial cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356908"}
{"pmid": "4356910", "title": "Derivatives of aziridine as inactivants for foot-and-mouth disease virus vaccines.", "content": "Derivatives of aziridine as inactivants for foot-and-mouth disease virus vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356910"}
{"pmid": "4356909", "title": "Pediatric oncology.", "content": "Pediatric oncology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356909"}
{"pmid": "4356911", "title": "The influence of short ether anesthesia on some liver enzyme activities in the rat.", "content": "The influence of short ether anesthesia on some liver enzyme activities in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356911"}
{"pmid": "4356913", "title": "A stable uterine binding protein preparation for the assay of plasma oestriol in pregnancy.", "content": "A stable uterine binding protein preparation for the assay of plasma oestriol in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356913"}
{"pmid": "4356912", "title": "Collagenolytic activity in rheumatoid synovial tissue.", "content": "Collagenolytic activity in rheumatoid synovial tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356912"}
{"pmid": "4356914", "title": "Physical and chemical factors influencing the reliability of the assay of androgens by competitive protein binding.", "content": "Physical and chemical factors influencing the reliability of the assay of androgens by competitive protein binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356914"}
{"pmid": "4356915", "title": "The effects of adrenalin, glucagon, insulin and dibutyryl cyclic AMP on liver and serum alpha-amylase activities in the rat.", "content": "The effects of adrenalin, glucagon, insulin and dibutyryl cyclic AMP on liver and serum alpha-amylase activities in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356915"}
{"pmid": "4356916", "title": "Alcohol dehydrogenase in Mucorales. II.", "content": "Alcohol dehydrogenase in Mucorales. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356916"}
{"pmid": "4356933", "title": "Activity and some properties of choline kinase, cholinephosphate cytidyltransferase and choline phosphotransferase during liver development in the rat.", "content": "Activity and some properties of choline kinase, cholinephosphate cytidyltransferase and choline phosphotransferase during liver development in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356933"}
{"pmid": "4356934", "title": "Isolation and characterization of a sialoglycolipid from the sea urchin Strongylocentrotus intermedius.", "content": "Isolation and characterization of a sialoglycolipid from the sea urchin Strongylocentrotus intermedius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356934"}
{"pmid": "4356929", "title": "In vitro and in vivo studies with Epstein-Barr virus (EBV). A review.", "content": "In vitro and in vivo studies with Epstein-Barr virus (EBV). A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356929"}
{"pmid": "4356936", "title": "The role of the raphe nuclei in the regulation of ponto-geniculo-occipital wave activity.", "content": "The role of the raphe nuclei in the regulation of ponto-geniculo-occipital wave activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356936"}
{"pmid": "4356930", "title": "Epstein-Barr virus: stimulation by 5'-iododeoxyuridine or 5'-bromodeoxyuridine in human lymphoblastoid cells from a rhabdomyosarcoma.", "content": "Epstein-Barr virus: stimulation by 5'-iododeoxyuridine or 5'-bromodeoxyuridine in human lymphoblastoid cells from a rhabdomyosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356930"}
{"pmid": "4356937", "title": "Electrophysiology of the frontal granular cortex. I. Patterns of focal field potentials evoked by stimulations of dorsomedial thalamus in conscious monkey.", "content": "Electrophysiology of the frontal granular cortex. I. Patterns of focal field potentials evoked by stimulations of dorsomedial thalamus in conscious monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356937"}
{"pmid": "4356938", "title": "Transmitter role of serotonin in identified synapses in Aplysia nervous system.", "content": "Transmitter role of serotonin in identified synapses in Aplysia nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356938"}
{"pmid": "4356941", "title": "The effect of number of stimuli and rate of stimulation on the inhibition by PGE1 of adrenergic transmission.", "content": "The effect of number of stimuli and rate of stimulation on the inhibition by PGE1 of adrenergic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356941"}
{"pmid": "4356942", "title": "Selective microvascular constrictor actions of some neurohypophyseal peptides.", "content": "Selective microvascular constrictor actions of some neurohypophyseal peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356942"}
{"pmid": "4356943", "title": "A controlled trial of a new combined preparation for the treatment of constipation in geriatric patients.", "content": "A controlled trial of a new combined preparation for the treatment of constipation in geriatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356943"}
{"pmid": "4356945", "title": "The frequency of excretion of cysts of Entamoeba histolytica in known cases of non-dysenteric amoebic colitis based on 21 stool examinations.", "content": "The frequency of excretion of cysts of Entamoeba histolytica in known cases of non-dysenteric amoebic colitis based on 21 stool examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356945"}
{"pmid": "4356946", "title": "Studies on proteolytic activity of mycoplasmas: the preparation and properties of gelatinolytic enzymes from strains of Mycoplasma arthritidis.", "content": "Studies on proteolytic activity of mycoplasmas: the preparation and properties of gelatinolytic enzymes from strains of Mycoplasma arthritidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356946"}
{"pmid": "4356947", "title": "Formation of extracellular haemolysin by Aeromonas hydrophila in relation to protease and staphylolytic enzyme.", "content": "Formation of extracellular haemolysin by Aeromonas hydrophila in relation to protease and staphylolytic enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356947"}
{"pmid": "4356948", "title": "Hospital discharge planning: a hospital's responsibility to the patient and the community.", "content": "Hospital discharge planning: a hospital's responsibility to the patient and the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356948"}
{"pmid": "4356950", "title": "Diagnosis, prognosis and treatment of peripheral neuropathies.", "content": "Diagnosis, prognosis and treatment of peripheral neuropathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356950"}
{"pmid": "4356951", "title": "Polishing dental enamel.", "content": "Polishing dental enamel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356951"}
{"pmid": "4356939", "title": "Effect of dibutyryl cyclic AMP on cell proliferation of adenohypophysis in organ culture. Preliminary report.", "content": "Effect of dibutyryl cyclic AMP on cell proliferation of adenohypophysis in organ culture. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356939"}
{"pmid": "4356963", "title": "Hemoglobin H-beta-thalassemia.", "content": "Hemoglobin H-beta-thalassemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356963"}
{"pmid": "4356964", "title": "The problem of pathogenicity in parasitic entamoeba.", "content": "The problem of pathogenicity in parasitic entamoeba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356964"}
{"pmid": "4356967", "title": "Gas-phase electron paramagnetic resonance detection of nitric oxide and nitrogen dioxide in polluted air.", "content": "Gas-phase electron paramagnetic resonance detection of nitric oxide and nitrogen dioxide in polluted air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356967"}
{"pmid": "4356969", "title": "The degeneration and disappearance of the centrioles during the development of the rat spermatozoon.", "content": "The degeneration and disappearance of the centrioles during the development of the rat spermatozoon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356969"}
{"pmid": "4356968", "title": "Localization and correltion of catecholamine-containing cells with adenyl cyclase nd phosphodiesterase activities in the human fetal heart.", "content": "Localization and correltion of catecholamine-containing cells with adenyl cyclase nd phosphodiesterase activities in the human fetal heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356968"}
{"pmid": "4356970", "title": "X-ray abnormalities in tetra X females. (Report on two cases).", "content": "X-ray abnormalities in tetra X females. (Report on two cases).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356970"}
{"pmid": "4356971", "title": "Artificial proteolipids: cytochrome c-detergent complexes soluble in isooctane.", "content": "Artificial proteolipids: cytochrome c-detergent complexes soluble in isooctane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356971"}
{"pmid": "4356972", "title": "\"Super-reduction\" of chromatium high-potential iron-sulphur protein in the presence of dimethyl sulphoxide.", "content": "\"Super-reduction\" of chromatium high-potential iron-sulphur protein in the presence of dimethyl sulphoxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356972"}
{"pmid": "4356973", "title": "The effect of cyclic AMP on anaerobic growth of Escherichia coli.", "content": "The effect of cyclic AMP on anaerobic growth of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356973"}
{"pmid": "4356974", "title": "A synthetic tripeptide which increases survival of normal liver cells, and stimulates growth in hepatoma cells.", "content": "A synthetic tripeptide which increases survival of normal liver cells, and stimulates growth in hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356974"}
{"pmid": "4356975", "title": "A specific glucocorticoid binding macromolecule of rabbit uterine cytosol.", "content": "A specific glucocorticoid binding macromolecule of rabbit uterine cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356975"}
{"pmid": "4356976", "title": "Periodic change in the content of adenosine 3'5'-cyclic monophosphate with close relation to the cycle of cleavage in the sea urchin egg.", "content": "Periodic change in the content of adenosine 3'5'-cyclic monophosphate with close relation to the cycle of cleavage in the sea urchin egg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356976"}
{"pmid": "4356977", "title": "A cytoplasmic membrane-associated DNA from rapidly proliferating tissue.", "content": "A cytoplasmic membrane-associated DNA from rapidly proliferating tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356977"}
{"pmid": "4356978", "title": "Resolutions and identification of the core deoxynucleoproteins of the simian virus 40.", "content": "Resolutions and identification of the core deoxynucleoproteins of the simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356978"}
{"pmid": "4356979", "title": "Cyclic nucleotide-independent protein kinase from pea shoots.", "content": "Cyclic nucleotide-independent protein kinase from pea shoots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356979"}
{"pmid": "4356980", "title": "Stimulation of ovarian cyclic guanosine 3',5'-monophosphate levels by the subunits of human chorionic gonadotropin.", "content": "Stimulation of ovarian cyclic guanosine 3',5'-monophosphate levels by the subunits of human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356980"}
{"pmid": "4356981", "title": "Studies on the immunochemical and functional similarities among iron-sulfur proteins involved in mitochondrial steroid hydroxylations.", "content": "Studies on the immunochemical and functional similarities among iron-sulfur proteins involved in mitochondrial steroid hydroxylations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356981"}
{"pmid": "4356982", "title": "Carbohydrate composition of lipoprotein apoproteins isolated from rat plasma and from the livers of rats fed orotic acid.", "content": "Carbohydrate composition of lipoprotein apoproteins isolated from rat plasma and from the livers of rats fed orotic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356982"}
{"pmid": "4356983", "title": "Inhibition of protein synthesis directed by added viral and cellular messenger RNAs in extracts of interferon-treated Ehrlich ascites tumor cells. Location and dominance of the inhibitor(s).", "content": "Inhibition of protein synthesis directed by added viral and cellular messenger RNAs in extracts of interferon-treated Ehrlich ascites tumor cells. Location and dominance of the inhibitor(s).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356983"}
{"pmid": "4356985", "title": "Multiple cytochromes b in Mycobacterium phlei.", "content": "Multiple cytochromes b in Mycobacterium phlei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356985"}
{"pmid": "4356987", "title": "A follow-up study of 211 treated male alcoholic addicts.", "content": "A follow-up study of 211 treated male alcoholic addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356987"}
{"pmid": "4356984", "title": "The stimulation of dopa decarboxylase activity by ecdysone and its enhancement by cyclic AMP in adult mosquitoes.", "content": "The stimulation of dopa decarboxylase activity by ecdysone and its enhancement by cyclic AMP in adult mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356984"}
{"pmid": "4356986", "title": "The phosphorylation of troponin B by phosphorylase b kinase in skeletal muscle of mice carrying the phosphorylase b kinase deficiency gene.", "content": "The phosphorylation of troponin B by phosphorylase b kinase in skeletal muscle of mice carrying the phosphorylase b kinase deficiency gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356986"}
{"pmid": "4356988", "title": "Hypothalamo-hypophysial neurosecretion. II. Hypophysectomy, ACTH and metopiron treatment in Bufo andersonii.", "content": "Hypothalamo-hypophysial neurosecretion. II. Hypophysectomy, ACTH and metopiron treatment in Bufo andersonii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356988"}
{"pmid": "4356991", "title": "Virulence of E. histolytica strains isolated from cases of amoebiasis in New Delhi, India.", "content": "Virulence of E. histolytica strains isolated from cases of amoebiasis in New Delhi, India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356991"}
{"pmid": "4356989", "title": "The Poland syndrome-clinical and genealogical data, dermatoglyphic analysis, and incidence.", "content": "The Poland syndrome-clinical and genealogical data, dermatoglyphic analysis, and incidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356989"}
{"pmid": "4356990", "title": "Morphogenesis of calcium laden cytoplasmic bodies in malakoplakia of the skin. An electron microscopic study.", "content": "Morphogenesis of calcium laden cytoplasmic bodies in malakoplakia of the skin. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356990"}
{"pmid": "4356992", "title": "Location of heme a in cytochrome a. II. Solvent perturbation spectroscopy of ferricytochrome a.", "content": "Location of heme a in cytochrome a. II. Solvent perturbation spectroscopy of ferricytochrome a.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356992"}
{"pmid": "4356993", "title": "Some characteristics of phosphorylation reactions in rat-liver mitochondria incubated without the addition of adenine nucleotides and their relation to substrate-level phosphorylation.", "content": "Some characteristics of phosphorylation reactions in rat-liver mitochondria incubated without the addition of adenine nucleotides and their relation to substrate-level phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356993"}
{"pmid": "4356995", "title": "Juvenile angiofibroma. Report of a case occurring within the mouth.", "content": "Juvenile angiofibroma. Report of a case occurring within the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356995"}
{"pmid": "4356994", "title": "Regulation of rabbit liver fructose diphosphatase. I. Reversible inactivation by oxidized glutathione.", "content": "Regulation of rabbit liver fructose diphosphatase. I. Reversible inactivation by oxidized glutathione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356994"}
{"pmid": "4356996", "title": "A hand sign.", "content": "A hand sign.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356996"}
{"pmid": "4356997", "title": "Studies on cyclic nucleotides in the adrenal gland. II. Properties of cyclic AMP dependent protein kinases in the adrenal gland.", "content": "Studies on cyclic nucleotides in the adrenal gland. II. Properties of cyclic AMP dependent protein kinases in the adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356997"}
{"pmid": "4356998", "title": "Antitumor activity of DL-1-beta-chloroethyl-2-chloromethylpiperidine hydrobromide (CAP-1) on some rodent tumors.", "content": "Antitumor activity of DL-1-beta-chloroethyl-2-chloromethylpiperidine hydrobromide (CAP-1) on some rodent tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356998"}
{"pmid": "4356999", "title": "The action of dibutyryl cyclic GMP (N2-2'-O-dibutyryl cyclic guanosine-3',5'-mono-phosphate) on the ileum of guinea pig.", "content": "The action of dibutyryl cyclic GMP (N2-2'-O-dibutyryl cyclic guanosine-3',5'-mono-phosphate) on the ileum of guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4356999"}
{"pmid": "4357000", "title": "Effect of serotonin, glucagon and other hormones on amylase secretion from rabbit parotid gland.", "content": "Effect of serotonin, glucagon and other hormones on amylase secretion from rabbit parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357000"}
{"pmid": "4357001", "title": "Specific pressor activity of angiotensins I and II.", "content": "Specific pressor activity of angiotensins I and II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357001"}
{"pmid": "4357002", "title": "The effect of oxytocin on renal blood flow and its distribution in the dog.", "content": "The effect of oxytocin on renal blood flow and its distribution in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357002"}
{"pmid": "4357013", "title": "Ultrastructure of the abnormal human trophoblast.", "content": "Ultrastructure of the abnormal human trophoblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357013"}
{"pmid": "4357014", "title": "A contribution to the knowledge of the hypo-beta-lipoproteinemia.", "content": "A contribution to the knowledge of the hypo-beta-lipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357014"}
{"pmid": "4357015", "title": "Paediatric pharmacology.", "content": "Paediatric pharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357015"}
{"pmid": "4357019", "title": "Lipid- and temperature-dependent structural changes in Acholeplasma laidlawii cell membranes.", "content": "Lipid- and temperature-dependent structural changes in Acholeplasma laidlawii cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357019"}
{"pmid": "4357018", "title": "Proteins from thermophilic microorganisms.", "content": "Proteins from thermophilic microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357018"}
{"pmid": "4357021", "title": "Action of snake venom hemorrhagic principles on isolated glomerular basement membrane.", "content": "Action of snake venom hemorrhagic principles on isolated glomerular basement membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357021"}
{"pmid": "4357022", "title": "Behçet's disease with recurrent facial paralysis.", "content": "Behçet's disease with recurrent facial paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357022"}
{"pmid": "4357020", "title": "Calcium binding by a plasma membrane fraction isolated from rat submandibular glands.", "content": "Calcium binding by a plasma membrane fraction isolated from rat submandibular glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357020"}
{"pmid": "4357023", "title": "A test for space clustering and its application to congenital limb defects in Cardiff.", "content": "A test for space clustering and its application to congenital limb defects in Cardiff.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357023"}
{"pmid": "4357025", "title": "Letter: Lipoprotein electrophoresis.", "content": "Letter: Lipoprotein electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357025"}
{"pmid": "4357017", "title": "Autotrophic CO2 assimilation and the evolution of ribulose diphosphate carboxylase.", "content": "Autotrophic CO2 assimilation and the evolution of ribulose diphosphate carboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357017"}
{"pmid": "4357024", "title": "Gel entrapment of antibody: a new strategy for facilitating both manual and automated radioimmunoassay.", "content": "Gel entrapment of antibody: a new strategy for facilitating both manual and automated radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357024"}
{"pmid": "4357029", "title": "Effect of cell chromosome number on simian virus 40 replication.", "content": "Effect of cell chromosome number on simian virus 40 replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357029"}
{"pmid": "4357030", "title": "Nuclear membranes from mammalian liver. VI. Glucose-6-phosphatase in rat liver, a cytochemical and biochemical study.", "content": "Nuclear membranes from mammalian liver. VI. Glucose-6-phosphatase in rat liver, a cytochemical and biochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357030"}
{"pmid": "4357031", "title": "Growth induction by serum or polyoma virus inhibits the aggregation of trypsinised suspensions of BHK21 tissue culture fibroblasts.", "content": "Growth induction by serum or polyoma virus inhibits the aggregation of trypsinised suspensions of BHK21 tissue culture fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357031"}
{"pmid": "4357032", "title": "Studies on cellular adhesion in tissue culture. XIIA. Some effects of prostaglandins and cyclic nucleotides.", "content": "Studies on cellular adhesion in tissue culture. XIIA. Some effects of prostaglandins and cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357032"}
{"pmid": "4357033", "title": "Contact-inhibited revertant cell lines isolated from SV40-transformed cells. V. Contact inhibition of sugar transport.", "content": "Contact-inhibited revertant cell lines isolated from SV40-transformed cells. V. Contact inhibition of sugar transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357033"}
{"pmid": "4357034", "title": "A permanent line of macrophages with normal activity in a primary antibody response in vitro.", "content": "A permanent line of macrophages with normal activity in a primary antibody response in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357034"}
{"pmid": "4357035", "title": "A Merkel cell nuclear inclusion.", "content": "A Merkel cell nuclear inclusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357035"}
{"pmid": "4357037", "title": "Scalp vesicles within the first week of life: a clue to early diagnosis of herpes neonatorum.", "content": "Scalp vesicles within the first week of life: a clue to early diagnosis of herpes neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357037"}
{"pmid": "4357038", "title": "Editorial: Leukocyte movement--in vitro and in vivo correlates.", "content": "Editorial: Leukocyte movement--in vitro and in vivo correlates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357038"}
{"pmid": "4357039", "title": "Defect of neutrophil motility in a child with recurrent bacterial infections and disseminated cytomegalovirus infection.", "content": "Defect of neutrophil motility in a child with recurrent bacterial infections and disseminated cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357039"}
{"pmid": "4357041", "title": "International certificates of vaccination.", "content": "International certificates of vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357041"}
{"pmid": "4357040", "title": "Renovascular hypertension secondary to hydronephrosis in a solitary kidney.", "content": "Renovascular hypertension secondary to hydronephrosis in a solitary kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357040"}
{"pmid": "4357042", "title": "Long-term evaluation of single versus multiple courses of actinomycin D therapy of Wilms's tumor.", "content": "Long-term evaluation of single versus multiple courses of actinomycin D therapy of Wilms's tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357042"}
{"pmid": "4357043", "title": "Lymphocyte inclusions in newborns of mothers with systemic lupus erythematosus.", "content": "Lymphocyte inclusions in newborns of mothers with systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357043"}
{"pmid": "4357044", "title": "Vitamin D-induced synthesis of mRNA for calcium-binding protein.", "content": "Vitamin D-induced synthesis of mRNA for calcium-binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357044"}
{"pmid": "4357045", "title": "Antibodies to simian C-type virus antigen in sera of gibbons (Hylobates sp.).", "content": "Antibodies to simian C-type virus antigen in sera of gibbons (Hylobates sp.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357045"}
{"pmid": "4357046", "title": "Leakage of cyclic AMP from human diploid fibroblasts in tissue culture.", "content": "Leakage of cyclic AMP from human diploid fibroblasts in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357046"}
{"pmid": "4357047", "title": "Postpartum bilateral femoral neuropathy.", "content": "Postpartum bilateral femoral neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357047"}
{"pmid": "4357049", "title": "Choline phosphokinase, phosphorylcholine cytidyltransferase and CDP-choline: 1,2-diglyceride cholinephosphotransferase activity in developing rat lung.", "content": "Choline phosphokinase, phosphorylcholine cytidyltransferase and CDP-choline: 1,2-diglyceride cholinephosphotransferase activity in developing rat lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357049"}
{"pmid": "4357050", "title": "Enhancement of viral infectivity by cytochalasin.", "content": "Enhancement of viral infectivity by cytochalasin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357050"}
{"pmid": "4357051", "title": "A comparison of the virus-specific polypeptides of encephalomyocarditis virus, human rhinovirus-1A, and poliovirus.", "content": "A comparison of the virus-specific polypeptides of encephalomyocarditis virus, human rhinovirus-1A, and poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357051"}
{"pmid": "4357052", "title": "Avian oncornavirus-induced tumor antigens of embryonic and unknown origin.", "content": "Avian oncornavirus-induced tumor antigens of embryonic and unknown origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357052"}
{"pmid": "4357053", "title": "Rescue of vesicular stomatitis virus from interferon-induced resistance by superinfection with vaccinia virus. I. Rescue in cell cultures from different species.", "content": "Rescue of vesicular stomatitis virus from interferon-induced resistance by superinfection with vaccinia virus. I. Rescue in cell cultures from different species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357053"}
{"pmid": "4357054", "title": "Rescue of vesicular stomatitis virus from interferon-induced resistance by superinfection with vaccinia virus. II. Effect of UV-inactivated vaccinia and metabolic inhibitors.", "content": "Rescue of vesicular stomatitis virus from interferon-induced resistance by superinfection with vaccinia virus. II. Effect of UV-inactivated vaccinia and metabolic inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357054"}
{"pmid": "4357055", "title": "Early synthesis of virus-specific RNA and DNA in cells rapidly transformed with Rous sarcoma virus.", "content": "Early synthesis of virus-specific RNA and DNA in cells rapidly transformed with Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357055"}
{"pmid": "4357056", "title": "DNA replication in SV40-infected cells. IX. The inhibition of a gap-filling step during discontinuous synthesis of SV40 DNA.", "content": "DNA replication in SV40-infected cells. IX. The inhibition of a gap-filling step during discontinuous synthesis of SV40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357056"}
{"pmid": "4357059", "title": "Cytotoxic action of spleen lymphocytes to simian virus 40-induced tumor cells.", "content": "Cytotoxic action of spleen lymphocytes to simian virus 40-induced tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357059"}
{"pmid": "4357060", "title": "Tumorigenesis of adenovirus-SV 40 hybrids in hamsters.", "content": "Tumorigenesis of adenovirus-SV 40 hybrids in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357060"}
{"pmid": "4357061", "title": "Mixed mesodermal tumor of the ovary.", "content": "Mixed mesodermal tumor of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357061"}
{"pmid": "4357062", "title": "Fine structure of the differentiating acini in submandibular glands of isoproterenol-treated rats.", "content": "Fine structure of the differentiating acini in submandibular glands of isoproterenol-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357062"}
{"pmid": "4357063", "title": "Large inclusions in receptor cells of the amphibian lateral line.", "content": "Large inclusions in receptor cells of the amphibian lateral line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357063"}
{"pmid": "4357064", "title": "The corticotroph of the rat adenohypophysis: a comparative study.", "content": "The corticotroph of the rat adenohypophysis: a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357064"}
{"pmid": "4357067", "title": "Tracheal obstruction.", "content": "Tracheal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357067"}
{"pmid": "4357068", "title": "Cholinergic responses and adrenergic-cholinergic interactions in the mesenteric vascular bed.", "content": "Cholinergic responses and adrenergic-cholinergic interactions in the mesenteric vascular bed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357068"}
{"pmid": "4357069", "title": "Effect of disulfiram on the urinary D-glucaric acid excretion and activity of some enzymes involved in drug metabolism in guinea-pig.", "content": "Effect of disulfiram on the urinary D-glucaric acid excretion and activity of some enzymes involved in drug metabolism in guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357069"}
{"pmid": "4357070", "title": "The action of polypeptides, amines and prostaglandins on isolated smooth muscle preparations of seminal vesicles and deferent ducts.", "content": "The action of polypeptides, amines and prostaglandins on isolated smooth muscle preparations of seminal vesicles and deferent ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357070"}
{"pmid": "4357072", "title": "Proceedings: The surgical treatment of nephroblastoma (Wilms' tumor).", "content": "Proceedings: The surgical treatment of nephroblastoma (Wilms' tumor).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357072"}
{"pmid": "4357073", "title": "Proceedings: Chemotherapy in Wilms' tumor. An appraisal.", "content": "Proceedings: Chemotherapy in Wilms' tumor. An appraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357073"}
{"pmid": "4357075", "title": "Herpesvirus cervicitis and cervical neoplasia. A cytologic review.", "content": "Herpesvirus cervicitis and cervical neoplasia. A cytologic review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357075"}
{"pmid": "4357074", "title": "Proceedings: Tumors of the adrenal cortex.", "content": "Proceedings: Tumors of the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357074"}
{"pmid": "4357076", "title": "Changing pattern of some pathologic parameters of mammary carcinoma.", "content": "Changing pattern of some pathologic parameters of mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357076"}
{"pmid": "4357077", "title": "Myoepithelioma of the palate. Report of a case with histochemical and electron microscopic observations.", "content": "Myoepithelioma of the palate. Report of a case with histochemical and electron microscopic observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357077"}
{"pmid": "4357065", "title": "Cortisol and growth hormone response to surgical stress during morphine anesthesia.", "content": "Cortisol and growth hormone response to surgical stress during morphine anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357065"}
{"pmid": "4357079", "title": "Hepatocellular carcinoma presenting with pathologic fracture due to bone metastases.", "content": "Hepatocellular carcinoma presenting with pathologic fracture due to bone metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357079"}
{"pmid": "4357078", "title": "Light and electron microscopic observations on a congenital insulinoma.", "content": "Light and electron microscopic observations on a congenital insulinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357078"}
{"pmid": "4357080", "title": "Hypoglycemia associated with lipid accumulation in primary hepatocellular carcinoma.", "content": "Hypoglycemia associated with lipid accumulation in primary hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357080"}
{"pmid": "4357082", "title": "Heart mitochondria oxidations of an Antarctic fish.", "content": "Heart mitochondria oxidations of an Antarctic fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357082"}
{"pmid": "4357081", "title": "Distribution of serum lipoproteins of selected vertebrates.", "content": "Distribution of serum lipoproteins of selected vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357081"}
{"pmid": "4357084", "title": "Suppressive effect of dexamethasone on morphine-induced adrenocorticoidogenesis in rat.", "content": "Suppressive effect of dexamethasone on morphine-induced adrenocorticoidogenesis in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357084"}
{"pmid": "4357085", "title": "Effect of synthetic corticotropins on human growth hormone secretion.", "content": "Effect of synthetic corticotropins on human growth hormone secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357085"}
{"pmid": "4357086", "title": "Effect of ACTH on the phosphorylation of proteins in subcellular fractions of rat adrenal glands.", "content": "Effect of ACTH on the phosphorylation of proteins in subcellular fractions of rat adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357086"}
{"pmid": "4357087", "title": "5Alpha-dihydrotestosterone \"receptor\" in the rat hypothalamus.", "content": "5Alpha-dihydrotestosterone \"receptor\" in the rat hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357087"}
{"pmid": "4357088", "title": "Nuclear and extranuclear mutations in yeast induced by ethyl methanesulfonate.", "content": "Nuclear and extranuclear mutations in yeast induced by ethyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357088"}
{"pmid": "4357090", "title": "Poliovirus antibody in milk and sera of lactating women.", "content": "Poliovirus antibody in milk and sera of lactating women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357090"}
{"pmid": "4357091", "title": "Quantification of antipoliovirus antibodies in human and simian sera.", "content": "Quantification of antipoliovirus antibodies in human and simian sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357091"}
{"pmid": "4357089", "title": "The production of migration inhibitory factor (MIF) in rabbit lymphocytes by other than immunological mechanism.", "content": "The production of migration inhibitory factor (MIF) in rabbit lymphocytes by other than immunological mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357089"}
{"pmid": "4357092", "title": "Combined action of antiamoebic drugs and antibiotics on axenically grown Entamoeba histolytica.", "content": "Combined action of antiamoebic drugs and antibiotics on axenically grown Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357092"}
{"pmid": "4357093", "title": "Adenovirus infections in West Bengal. I. Persistence of viruses in infants and young children.", "content": "Adenovirus infections in West Bengal. I. Persistence of viruses in infants and young children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357093"}
{"pmid": "4357094", "title": "Encephalomyocarditis virus activity in Mus booduga (Gray) in Barur Village (1961-1962), Sagar KFD area, Mysore State, India.", "content": "Encephalomyocarditis virus activity in Mus booduga (Gray) in Barur Village (1961-1962), Sagar KFD area, Mysore State, India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357094"}
{"pmid": "4357095", "title": "Pseudomonas cepacia tricuspid endocarditis: treatment with trimethoprim, sulfonamide, and polymyxin B.", "content": "Pseudomonas cepacia tricuspid endocarditis: treatment with trimethoprim, sulfonamide, and polymyxin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357095"}
{"pmid": "4357096", "title": "Sulfonamide structure-activity relationships in a cell-free system. 2. Proof for the formation of a sulfonamide-containing folate analog.", "content": "Sulfonamide structure-activity relationships in a cell-free system. 2. Proof for the formation of a sulfonamide-containing folate analog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357096"}
{"pmid": "4357097", "title": "Transcription of mouse mammary tumor virus genes in tissues from high and low tumor incidence mouse strains.", "content": "Transcription of mouse mammary tumor virus genes in tissues from high and low tumor incidence mouse strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357097"}
{"pmid": "4357098", "title": "Letter: On the source of \"minor thymine\" in DNA from a Novik off rat hepatoma cell line.", "content": "Letter: On the source of \"minor thymine\" in DNA from a Novik off rat hepatoma cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357098"}
{"pmid": "4357099", "title": "Ganglion of the posterior tibial nerve. Case report.", "content": "Ganglion of the posterior tibial nerve. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357099"}
{"pmid": "4357100", "title": "Identification of urinary metabolites of p-phenoxyphenol methanesulfonate in rat and man.", "content": "Identification of urinary metabolites of p-phenoxyphenol methanesulfonate in rat and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357100"}
{"pmid": "4357101", "title": "Colorimetric determination of dipyrone.", "content": "Colorimetric determination of dipyrone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357101"}
{"pmid": "4357102", "title": "Acetonitrile-diatomaceous earth column for separation of steroids and other compounds.", "content": "Acetonitrile-diatomaceous earth column for separation of steroids and other compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357102"}
{"pmid": "4357104", "title": "Far advanced malignant external otitis: report of a survival.", "content": "Far advanced malignant external otitis: report of a survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357104"}
{"pmid": "4357106", "title": "Infectious herpesvirus DNA.", "content": "Infectious herpesvirus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357106"}
{"pmid": "4357105", "title": "Differential inhibition of catabolite-sensitive enzyme induction by intercalating dyes.", "content": "Differential inhibition of catabolite-sensitive enzyme induction by intercalating dyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357105"}
{"pmid": "4357107", "title": "Controlled expression of SV40 genome.", "content": "Controlled expression of SV40 genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357107"}
{"pmid": "4357108", "title": "Adenine nucleotide-mediated subunit exchange between isoenzymes of glyceraldehyde-3-phosphate dehydrogenase.", "content": "Adenine nucleotide-mediated subunit exchange between isoenzymes of glyceraldehyde-3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357108"}
{"pmid": "4357109", "title": "Interaction of cytochrome oxidases aa3 and d with nitrite.", "content": "Interaction of cytochrome oxidases aa3 and d with nitrite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357109"}
{"pmid": "4357110", "title": "Characterisation of the 3'-terminus of Sindbis virion RNA.", "content": "Characterisation of the 3'-terminus of Sindbis virion RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357110"}
{"pmid": "4357111", "title": "Activation of phosphofructokinase by stimulants of cell multiplication.", "content": "Activation of phosphofructokinase by stimulants of cell multiplication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357111"}
{"pmid": "4357112", "title": "Activation of methaemoglobin peroxidase by inositol hexaphosphate.", "content": "Activation of methaemoglobin peroxidase by inositol hexaphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357112"}
{"pmid": "4357113", "title": "Myopathy associated with Marfan's syndrome. Fine structural and histochemical observations.", "content": "Myopathy associated with Marfan's syndrome. Fine structural and histochemical observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357113"}
{"pmid": "4357114", "title": "Study of long-term anticholinesterase therapy. Effects on neuromuscular transmission and on motor end-plate fine structure.", "content": "Study of long-term anticholinesterase therapy. Effects on neuromuscular transmission and on motor end-plate fine structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357114"}
{"pmid": "4357115", "title": "The effect of sleep on spike-wave discharges in absence seizures.", "content": "The effect of sleep on spike-wave discharges in absence seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357115"}
{"pmid": "4357117", "title": "Patterns of faecal porphyrin excretion in the hepatocutaneous porphyrias. Thin-layer chromatography of their methyl esters.", "content": "Patterns of faecal porphyrin excretion in the hepatocutaneous porphyrias. Thin-layer chromatography of their methyl esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357117"}
{"pmid": "4357118", "title": "Extensive resection of primary malignant tumors of the left cerebral hemisphere.", "content": "Extensive resection of primary malignant tumors of the left cerebral hemisphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357118"}
{"pmid": "4357119", "title": "Endemic goiter in Greece: nutritional status, growth, and skeletal development of goitrous and non goitrous populations.", "content": "Endemic goiter in Greece: nutritional status, growth, and skeletal development of goitrous and non goitrous populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357119"}
{"pmid": "4357121", "title": "Increased detection of occult breast carcinoma after more thorough histologic examination of breast biopsies.", "content": "Increased detection of occult breast carcinoma after more thorough histologic examination of breast biopsies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357121"}
{"pmid": "4357120", "title": "Standardized management of breast specimens recommended by Pathology Working Group, Breast Cancer Task Force.", "content": "Standardized management of breast specimens recommended by Pathology Working Group, Breast Cancer Task Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357120"}
{"pmid": "4357123", "title": "Cell-mediated immunity to herpes simplex virus in man.", "content": "Cell-mediated immunity to herpes simplex virus in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357123"}
{"pmid": "4357122", "title": "Congenital mesoblastic nephroma of infancy: report of a case with unusual clinical behavior.", "content": "Congenital mesoblastic nephroma of infancy: report of a case with unusual clinical behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357122"}
{"pmid": "4357125", "title": "Vasoactive substances in the circulation of the pregnant dog during acute fetal ischemia.", "content": "Vasoactive substances in the circulation of the pregnant dog during acute fetal ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357125"}
{"pmid": "4357124", "title": "Bacteriology and in vitro antimicrobial susceptibility of the Pseudomonas fluorescens group isolated from clinical specimens.", "content": "Bacteriology and in vitro antimicrobial susceptibility of the Pseudomonas fluorescens group isolated from clinical specimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357124"}
{"pmid": "4357126", "title": "Effect of oxytocin on the perfused human placenta in vitro.", "content": "Effect of oxytocin on the perfused human placenta in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357126"}
{"pmid": "4357127", "title": "Herpes genitalis treated by photodynamic inactivation of virus.", "content": "Herpes genitalis treated by photodynamic inactivation of virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357127"}
{"pmid": "4357128", "title": "The metabolic effects of halothane on mammalian hepatoma cells in vitro. II. Inhibition of DNA synthesis.", "content": "The metabolic effects of halothane on mammalian hepatoma cells in vitro. II. Inhibition of DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357128"}
{"pmid": "4357129", "title": "Decreased cerebrospinal fluid glucose level in herpes zoster meningitis. Report of a case.", "content": "Decreased cerebrospinal fluid glucose level in herpes zoster meningitis. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357129"}
{"pmid": "4357130", "title": "On the treatment of rapid eye movement narcolepsy.", "content": "On the treatment of rapid eye movement narcolepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357130"}
{"pmid": "4357131", "title": "Adenyl cyclase in normal and pathologic human muscle.", "content": "Adenyl cyclase in normal and pathologic human muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357131"}
{"pmid": "4357133", "title": "The behaviour of carcinoma of the large bowel in man following transplantation into immune deprived mice.", "content": "The behaviour of carcinoma of the large bowel in man following transplantation into immune deprived mice. The growth of carcinoma of the human large bowel was studied in the first 2 passages in immune deprived mice. The tumours were obtained from large bowel resections on 3 people. There was a strong histological similarity between the patient's tumour and the tumour that grew subcutaneously in the mice 2-8 months after implantation. One dissimilarity observed was a higher mitotic index in some of the tumours growing in the immune deprived animals. In the second passage of the bowel tumours, cells were implanted into groups of 8-10 animals in the following sites: subcutaneous, intramuscular, intravenous, intrahepatic, intraperitoneal and intrathoracic. Growth of tumour was observed from all 3 tumours when they were implanted subcutaneously, intramuscularly, intraperitoneally and intrathoracically. Infiltration of muscle by tumour was a frequent finding. Lung metastases developed after intravenous injection of cells in 1 of the 3 tumours. In none of the 3 tumours did growth follow injection of cells directly into the substance of the liver. On no occasions were spontaneous metastases observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357133"}
{"pmid": "4357132", "title": "Immunogenicity of rat hepatoma membrane fractions.", "content": "Immunogenicity of rat hepatoma membrane fractions. The principal expression of immunity elicited in syngeneic rats immunized with rat hepatoma membrane fractions was the development of a tumour specific antibody response. This antibody was demonstrable by membrane immunofluorescence staining of viable hepatoma cells in suspension and the sera exhibited complement dependent cytotoxicity for cultured hepatoma cells. In the absence of complement, however, membrane immune sera were highly \"blocking\", protecting plated hepatoma cells from attack by sensitized lymph node cells. The cell mediated immune response elicited by hepatoma membrane immunization was weak, as evaluated by the colony inhibitory activity of lymph node cells for hepatoma cells in vitro or the adoptive transfer of immunity with peritoneal exudate cells. Correlated with this overall pattern of immune response, membrane immunization did not elicit tumour rejection reactions. These findings are relevant to current views that humoral factors operate antagonistically to limit cell mediated immunity to tumours. A further relevant feature was the observation that membrane immunization, eliciting a prominent humoral immune reaction, conditioned the recipients so that they subsequently failed to elicit a tumour rejection immunity on treatment with irradiated tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357132"}
{"pmid": "4357135", "title": "Substitution of beclomethasone aerosol for oral prednisolone in the treatment of chronic asthma.", "content": "Substitution of beclomethasone aerosol for oral prednisolone in the treatment of chronic asthma. In a double-blind study 10 patients with chronic asthma received beclomethasone dipropionate 400 mug daily in a Freon propellant from a pressurized dispenser, and 10 patients received the Freon propellant alone. At the start of the trial each patient was receiving long-term maintenance treatment with oral prednisolone in a dose of 7.5 to 15 mg daily. The daily dose of prednisolone was reduced by 1 mg every four weeks and the patient's progress followed by regular clinical assessment and studies of pituitary-adrenal function. The trial was continued until the dose of prednisolone was reduced to zero or until asthmatic symptoms increased to an unacceptable level.In the 10 patients who received beclomethasone the mean maintenance dose of oral prednisolone was reduced by 5.6 mg/day but in only two cases could this drug be withdrawn completely. In the placebo group the mean reduction in dose was only 1.3 mg, thus there was a significant difference between the two groups (P <0.01). Studies of pituitary-adrenal function showed that a normal adrenal response to tetracosactrin stimulation returned only in the two patients from whom prednisolone was withdrawn.Hence the addition of beclomethasone dipropionate by inhalation to systemic corticosteroid therapy allows useful reductions to be made in the oral maintenance doses of corticosteroid. Reductions must be made with caution since there is wide individual variation in response to beclomethasone and in only a minority of patients can oral treatment by completely withdrawn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357135"}
{"pmid": "4357136", "title": "Letter: Type IV hyperlipidaemia in cord blood.", "content": "Letter: Type IV hyperlipidaemia in cord blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357136"}
{"pmid": "4357134", "title": "Transplantation of human tumour to immune deprived mice treated with anti-thymocyte serum.", "content": "Transplantation of human tumour to immune deprived mice treated with anti-thymocyte serum. Five out of 18 primary explants of human carcinomata obtained at operation have been grown progressively for a minimum of one month in thymectomized, x-irradiated mice reconstituted with syngeneic bone marrow and subsequently treated also with anti-thymocyte serum. All the tumours which proliferated were of gastrointestinal origin, growing locally but not metastasizing although direct invasion of the ribs occurred in one case. No implanted breast carcinomata grew in this system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357134"}
{"pmid": "4357139", "title": "Editorial: Neonatal kidney tumours.", "content": "Editorial: Neonatal kidney tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357139"}
{"pmid": "4357138", "title": "Changes in skeletal mineral in patients on prolonged maintenance dialysis.", "content": "Changes in skeletal mineral in patients on prolonged maintenance dialysis. The measurement of bone loss in patients undergoing maintenance dialysis over a period of two and a half years is reported. The tendency to lose bone is a likely event in renal failure, but depends more on the individual patient than on the type of dialysis used, provided that steps are taken to prevent avoidable calcium loss during dialysis. Vitamin D therapy was an important factor in preventing bone loss in some cases. The tendency to lose bone more readily when both kidneys were absent may have reflected a deficiency of 1-25 dihydrocholecalciferol. On the other hand, bone loss was also observed in transplanted patients. The need to measure bone loss at regular intervals once renal failure has been diagnosed is stressed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357138"}
{"pmid": "4357137", "title": "Problems of interpretation of laboratory findings in the old.", "content": "Problems of interpretation of laboratory findings in the old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357137"}
{"pmid": "4357140", "title": "Letter: Coma and convulsions associated with vincristine therapy.", "content": "Letter: Coma and convulsions associated with vincristine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357140"}
{"pmid": "4357141", "title": "Pediatric infections with respiratory syncytial virus.", "content": "Pediatric infections with respiratory syncytial virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357141"}
{"pmid": "4357143", "title": "NADH preparations as they affect reliability of serum lactate dehydrogenase determinations.", "content": "NADH preparations as they affect reliability of serum lactate dehydrogenase determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357143"}
{"pmid": "4357142", "title": "Respiratory syncytial virus infections in children in Montreal: a retrospective study.", "content": "Respiratory syncytial virus infections in children in Montreal: a retrospective study. Seventy-seven hospitalized children from whom respiratory syncytial virus was subsequently isolated were studied in retrospect. This demonstrated the association of host invasion by this agent with an acute respiratory disease requiring hospitalization for approximately one week.Boys considerably outnumbered girls, the average age was 7.5 months, and in 56% the admission diagnosis was \"bronchiolitis\". Cough and difficulty in breathing were the most common presenting complaints and \"pneumonia\" the most common radiological diagnosis. Nearly half the patients also harboured accepted disease-causing bacterial pathogens. All the patients recovered and have remained well.The appearance of the virus in Montreal was seasonal, beginning in late autumn and terminating in early spring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357142"}
{"pmid": "4357144", "title": "Residual fluorescence as an index of purity of reduced nicotinamide adenine dinucleotide.", "content": "Residual fluorescence as an index of purity of reduced nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357144"}
{"pmid": "4357145", "title": "Improved automated determination of bound N-acetylneuraminic acid in serum.", "content": "Improved automated determination of bound N-acetylneuraminic acid in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357145"}
{"pmid": "4357146", "title": "Preparation of amine salts of thymolphthalein monophosphate and their use for measuring phosphatase activity.", "content": "Preparation of amine salts of thymolphthalein monophosphate and their use for measuring phosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357146"}
{"pmid": "4357147", "title": "Ferric chloride-impregnated silica gel for thin-layer chromatography of steroids.", "content": "Ferric chloride-impregnated silica gel for thin-layer chromatography of steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357147"}
{"pmid": "4357151", "title": "Proceedings: Comparison between collagenase activity in rectal biopsies and plasma carcinoembryonic antigen (CEA) levels in patients with carcinoma of the colon and rectum.", "content": "Proceedings: Comparison between collagenase activity in rectal biopsies and plasma carcinoembryonic antigen (CEA) levels in patients with carcinoma of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357151"}
{"pmid": "4357152", "title": "Proceedings: The association of a specific skin lesion with islet-cell tumours of the pancreas.", "content": "Proceedings: The association of a specific skin lesion with islet-cell tumours of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357152"}
{"pmid": "4357154", "title": "Wart-associated antigens. I. Isolation of tissue antigens using antibody immunoadsorbents.", "content": "Wart-associated antigens. I. Isolation of tissue antigens using antibody immunoadsorbents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357154"}
{"pmid": "4357155", "title": "Wart-associated antigens. II. Human immunity to viral structural proteins.", "content": "Wart-associated antigens. II. Human immunity to viral structural proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357155"}
{"pmid": "4357153", "title": "Contraction of isolated human breast cutaneous vascular smooth muscle.", "content": "Contraction of isolated human breast cutaneous vascular smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357153"}
{"pmid": "4357157", "title": "Ultrastructural studies of olivopontocerebellar atrophy.", "content": "Ultrastructural studies of olivopontocerebellar atrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357157"}
{"pmid": "4357156", "title": "Adherence of platelets to a collagen-coated surface: development of a quantitative method.", "content": "Adherence of platelets to a collagen-coated surface: development of a quantitative method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357156"}
{"pmid": "4357158", "title": "Primary brain and spinal cord tumors induced by human adenovirus type 12 in hamsters.", "content": "Primary brain and spinal cord tumors induced by human adenovirus type 12 in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357158"}
{"pmid": "4357160", "title": "Glomus tumors in the middle ear. I. An analysis of 46 patients.", "content": "Glomus tumors in the middle ear. I. An analysis of 46 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357160"}
{"pmid": "4357159", "title": "Microchemical studies of lipids, proteins and nucleic acids in polyoma virus-transformed hamster astroglia.", "content": "Microchemical studies of lipids, proteins and nucleic acids in polyoma virus-transformed hamster astroglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357159"}
{"pmid": "4357161", "title": "Surgically confirmed gallbladder disease, venous thromboembolism, and breast tumors in relation to postmenopausal estrogen therapy. A report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center.", "content": "Surgically confirmed gallbladder disease, venous thromboembolism, and breast tumors in relation to postmenopausal estrogen therapy. A report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center. A survey conducted by hospitals in the Boston area of 5339 postmenopausal women for the possible influence of estrogen-containing drugs on gall bladder disease, venous thromboembolism, and breast tumors found gall bladder disease to be the  only significantly increased risk (p less than .001).  The relative risk for postmenopausal estrogen users was 2.5 (95% confidence interval was from 1.5 to 4.2), and the incidence rate was 131/100,000 women per year.  Significant associations between estrogen use and the other diseases were not found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357161"}
{"pmid": "4357162", "title": "The influence of temperature and fibril stability on degradation of cartilage collagen by rheumatoid synovial collagenase.", "content": "The influence of temperature and fibril stability on degradation of cartilage collagen by rheumatoid synovial collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357162"}
{"pmid": "4357163", "title": "Phospholipids in biology and medicine (first of two parts).", "content": "Phospholipids in biology and medicine (first of two parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357163"}
{"pmid": "4357164", "title": "Editorial: Collagenase, cartilage and cortisol.", "content": "Editorial: Collagenase, cartilage and cortisol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357164"}
{"pmid": "4357165", "title": "A novel substituted guanidine with high activity in vitro against rhinoviruses.", "content": "A novel substituted guanidine with high activity in vitro against rhinoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357165"}
{"pmid": "4357166", "title": "Histamine H1 and H2-receptors at a ganglionic synapse.", "content": "Histamine H1 and H2-receptors at a ganglionic synapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357166"}
{"pmid": "4357167", "title": "Synthesis of poly(A) in vitro by purified virions of vesicular stomatitis virus.", "content": "Synthesis of poly(A) in vitro by purified virions of vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357167"}
{"pmid": "4357168", "title": "Affinity of 253Einsteinium for tumour tissue.", "content": "Affinity of 253Einsteinium for tumour tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357168"}
{"pmid": "4357169", "title": "Morphological transformation of enucleated Chinese hamster ovary cells by dibutyryl adenosine 3',5'-monophosphate and hormones.", "content": "Morphological transformation of enucleated Chinese hamster ovary cells by dibutyryl adenosine 3',5'-monophosphate and hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357169"}
{"pmid": "4357170", "title": "An immunological study of human brain tumors concerning the brain specific protein S-100 and 14.3.2.", "content": "An immunological study of human brain tumors concerning the brain specific protein S-100 and 14.3.2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357170"}
{"pmid": "4357171", "title": "Acrylamide neuropathy in rats. An electron microscopic study of degeneration and regeneration.", "content": "Acrylamide neuropathy in rats. An electron microscopic study of degeneration and regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357171"}
{"pmid": "4357172", "title": "Peripheral neuropathy in ageing rats fed clioquinol and a maize diet.", "content": "Peripheral neuropathy in ageing rats fed clioquinol and a maize diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357172"}
{"pmid": "4357173", "title": "The effect of perinatal undernutrition on perineurial diffusion barrier to exogenous protein. An experimental study on rat sciatic nerve.", "content": "The effect of perinatal undernutrition on perineurial diffusion barrier to exogenous protein. An experimental study on rat sciatic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357173"}
{"pmid": "4357174", "title": "The hypocalcemic response to protamine as a measure of bone resorption.", "content": "The hypocalcemic response to protamine as a measure of bone resorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357174"}
{"pmid": "4357175", "title": "Bovine mycoplasmas: cultural and biochemical studies. II.", "content": "Bovine mycoplasmas: cultural and biochemical studies. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357175"}
{"pmid": "4357176", "title": "Fine structural alterations of bovine peripheral pulmonary arteries in hypoxia-induced hypertension.", "content": "Fine structural alterations of bovine peripheral pulmonary arteries in hypoxia-induced hypertension. Cellular alterations of the distal bovine pulmonary arteries in hypoxia-induced pulmonary hypertension were studied. These lesions were related to pulmonary hemodynamic changes and contrasted to the cellular response observed in hyperkinetic pulmonary and systemic hypertension as well as other forms of vascular injury. Medial thickening and mild adventitial proliferation with an absence of intimal proliferative lesions related to a progressive increase in mean pulmonary arterial pressure and pulmonary vascular resistance were observed. Smooth muscle and endothelial cells exhibited distinct degenerative alterations in response to the maintained hypertensive state resulting from the lowered alveolar oxygen tension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357176"}
{"pmid": "4357178", "title": "Endocrine and immunologic studies in breast cancer.", "content": "Endocrine and immunologic studies in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357178"}
{"pmid": "4357177", "title": "Collagen-proteoglycan relationships in epiphyseal cartilage.", "content": "Collagen-proteoglycan relationships in epiphyseal cartilage. Columnar and hypertrophic zones of calf scapular cartilage were studied before and after extraction with 3 M guanidinium chloride (GuCl) and digestion with enzymes which degrade various components of the extracellular matrix. Morphologic and chemical analysis suggests that there are at least two anatomic pools of proteoglycan in this tissue. One, which resides between collagen fibrils, is extractable with GuCl. Another appears attached to collagen by strong bonds and is apparently not extractable with GuCl. This type of collagen-proteoglycan relationship is possibly restricted to epiphyseal cartilage. The morphology of the lacuna is different in the columnar and hypertrophic zones. Proteoglycans in the distal hypertrophic zone are less resistant to GuCl extraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357177"}
{"pmid": "4357181", "title": "Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium aphidicola.", "content": "Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium aphidicola. Aphidicolin is an antibiotic of novel structure produced by the mold Cephalosporium aphidicola. It is a potent inhibitor of cellular deoxyribonucleic acid synthesis, and it also strongly inhibits the growth of herpes simplex virus both in tissue culture and in the rabbit eye. Aphidicolin is active against iododeoxyuridine-resistant herpes virus, and does not itself readily induce the formation of drug-resistant strains of herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357181"}
{"pmid": "4357180", "title": "Inactivation of Herpesvirus hominis types 1 and 2 by silver nitrate in vitro and in vivo.", "content": "Inactivation of Herpesvirus hominis types 1 and 2 by silver nitrate in vitro and in vivo. Herpes simplex virus (HSV) types 1 and 2 (two strains each) were inactivated at different rates in vitro by 40 muM AgNO(3). The inactivation of HSV type 1 strains was virtually complete in 10 to 15 min, whereas almost half of the infectivity of HSV type 2 strains survived this exposure. One strain of type 1 inoculated into rabbit eyes was almost completely inactivated by 1% AgNO(3) solution dropped into the eye 20 min later, so that there was markedly reduced viral replication and less corneal herpetic disease. One strain of HSV type 2 in the rabbit eye was not effectively inactivated by 1% AgNO(3). From these results, it seems likely that AgNO(3) instillation into the eyes of a newborn who has passed through a birth canal infected with HSV might prevent eye infection with HSV type 1 but not with type 2. The greater resistance of HSV type 2 strains to chemical inactivation in vitro and in vivo may be of medical concern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357180"}
{"pmid": "4357182", "title": "Serum and urinary concentrations of cyclacillin in humans.", "content": "Serum and urinary concentrations of cyclacillin in humans. Cyclacillin is a semisynthetic penicillin produced from the penicillin nucleus (6-aminopenicillanic acid) by acylation with 1-aminohexanecarboxylic acid. The absorption and excretion characteristics of cyclacillin were defined in one completely randomized and three three-way crossover experiments. Mean peak serum cyclacillin levels appeared earlier and were fivefold higher than those obtained with equal doses of ampicillin. High serum cyclacillin concentrations were reached at 0.5 h and by 2 h were lower than ampicillin. Serum ampicillin concentrations peaked at 1.5 h, remaining slightly higher than those for cyclacillin for the next 4.5 h. The mean area for the cyclacillin curve was significantly superior to either of the ampicillin formulations. Mean serum concentrations of cyclacillin exhibited a smooth dose-response, approximately doubling in each instance as the dose was doubled from 250 to 500 and from 500 to 1,000 mg. High concentrations of cyclacillin were also demonstrated in urine. Neither ratio of drug to metabolite in the urine nor the percent of excretion was significantly affected by the dose level. Sixty-seven percent of the drug was excreted unchanged, and 17% was excreted as penicilloic acid, with most of the excretion occurring within 6 h of administration. In subjects given 500 mg of cyclacillin (four times daily) for 6 days, 2% of the drug was excreted as 1-aminocyclohexanecarboxylic acid, and approximately 55% (24 to 91%) was unchanged. Neither formation nor excretion of the former was sex dependent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357182"}
{"pmid": "4357185", "title": "Cellular events in protein tolerant inbred rats. I. The fate of thoracic duct lymphocytes and memory cells during tolerance induction to human serum albumin.", "content": "Cellular events in protein tolerant inbred rats. I. The fate of thoracic duct lymphocytes and memory cells during tolerance induction to human serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357185"}
{"pmid": "4357184", "title": "Selective cytotoxicity of peritoneal leucocytes for neoplastic cells.", "content": "Selective cytotoxicity of peritoneal leucocytes for neoplastic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357184"}
{"pmid": "4357186", "title": "Estrogen-sensitive cells. Hormone receptors in tumors and cells in culture.", "content": "Estrogen-sensitive cells. Hormone receptors in tumors and cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357186"}
{"pmid": "4357187", "title": "Cyclic AMP, pattern formation and movement in the slime mould, Dictyostelium discoideum.", "content": "Cyclic AMP, pattern formation and movement in the slime mould, Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357187"}
{"pmid": "4357189", "title": "Lag period of action of 25-hydroxycholecalciferol on bone collagen metabolism in vitamin D deficient rats.", "content": "Lag period of action of 25-hydroxycholecalciferol on bone collagen metabolism in vitamin D deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357189"}
{"pmid": "4357188", "title": "Inhibition of cyclic 3',5'-nucleotide phosphodiesterase activity by diuretics and other agents.", "content": "Inhibition of cyclic 3',5'-nucleotide phosphodiesterase activity by diuretics and other agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357188"}
{"pmid": "4357190", "title": "Effect of various prostaglandins and serotonin on protein secretion from rat exocrine pancreas.", "content": "Effect of various prostaglandins and serotonin on protein secretion from rat exocrine pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357190"}
{"pmid": "4357191", "title": "The rate limiting control of enzymes monoamine oxidase and catechol-O-methyl transferase in the foetus and the adult by adreno-cortical hormones.", "content": "The rate limiting control of enzymes monoamine oxidase and catechol-O-methyl transferase in the foetus and the adult by adreno-cortical hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357191"}
{"pmid": "4357192", "title": "Immunohistochemical demonstration of corticotrophic cells concentrated in the rostral zone of the pars intermedia of the mouse hypophysis.", "content": "Immunohistochemical demonstration of corticotrophic cells concentrated in the rostral zone of the pars intermedia of the mouse hypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357192"}
{"pmid": "4357193", "title": "Detection of encephalomyocarditis virus infection in animal cells by gas liquid chromatography.", "content": "Detection of encephalomyocarditis virus infection in animal cells by gas liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357193"}
{"pmid": "4357195", "title": "Influence of suramin on activity of some hydrolytic and oxidative enzymes of pseudoeosinophilic (heterophil) peripheral blood granulocytes in rabbits.", "content": "Influence of suramin on activity of some hydrolytic and oxidative enzymes of pseudoeosinophilic (heterophil) peripheral blood granulocytes in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357195"}
{"pmid": "4357197", "title": "Ultrastructure of cytoplasmic hyaline inclusions in a case of human hepatocarcinoma.", "content": "Ultrastructure of cytoplasmic hyaline inclusions in a case of human hepatocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357197"}
{"pmid": "4357196", "title": "Modification of the acute toxicity of mutagenic and carcinogenic chemicals in the mouse by prefeeding with antioxidants.", "content": "Modification of the acute toxicity of mutagenic and carcinogenic chemicals in the mouse by prefeeding with antioxidants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357196"}
{"pmid": "4357198", "title": "Virus-induced premature chromosome condensation (PCC) in single cells and G-bands of PCC-chromatin.", "content": "Virus-induced premature chromosome condensation (PCC) in single cells and G-bands of PCC-chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357198"}
{"pmid": "4357200", "title": "Presynaptic inhibition of adrenergic motor transmission in rat anococcygeus muscle by D-lysergic acid diethylamide (LSD).", "content": "Presynaptic inhibition of adrenergic motor transmission in rat anococcygeus muscle by D-lysergic acid diethylamide (LSD).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357200"}
{"pmid": "4357201", "title": "The effect of a bradykinin potentiating nonapeptide (BPP9a) on prolonged haemorrhagic shock in dogs.", "content": "The effect of a bradykinin potentiating nonapeptide (BPP9a) on prolonged haemorrhagic shock in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357201"}
{"pmid": "4357199", "title": "Cortical pyramidal tract interneurones and their sensitivity to L-glutamic acid.", "content": "Cortical pyramidal tract interneurones and their sensitivity to L-glutamic acid. 1. Pyramidal tract interneurones, defined as neurones which are activated synaptically as a result of pyramidal tract stimulation, have been identified in the rat cerebral cortex. The number of evoked spikes depended upon stimulus strength, and stimulation in a specific thalamic nucleus produced a burst of activity lasting for up to 1 sec.2. These cells are readily excited by a brief (50 msec) pulse of glutamate applied by micro-iontophoresis. Other, unidentified cells are not so responsive.3. Synaptically evoked spikes resulting from pyramidal tract stimulation can be blocked by the iontophoretic and I.P. administration of substances shown to antagonize glutamate excitation of cells.4. The results support suggestions that glutamic acid is a neurotransmitter in the cerebral cortex. The evidence presented further indicates that glutamic acid could be the transmitter released by the pyramidal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357199"}
{"pmid": "4357202", "title": "Involvement of calcium in the inhibitory effects of putative transmitter substances in the cerebral cortex.", "content": "Involvement of calcium in the inhibitory effects of putative transmitter substances in the cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357202"}
{"pmid": "4357204", "title": "Effect of vitamin D3 and other factors on phosphate absorption by the chick.", "content": "Effect of vitamin D3 and other factors on phosphate absorption by the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357204"}
{"pmid": "4357205", "title": "Activation of prolyl hydroxylase by ascorbic acid.", "content": "Activation of prolyl hydroxylase by ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357205"}
{"pmid": "4357206", "title": "Use of cross-finger flap for treatment of congenital broad constricting bands of the fingers.", "content": "Use of cross-finger flap for treatment of congenital broad constricting bands of the fingers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357206"}
{"pmid": "4357208", "title": "Intramolecular nucleophilic attack of an ureido group on the beta-lactam carbonyl moiety of penicillins.", "content": "Intramolecular nucleophilic attack of an ureido group on the beta-lactam carbonyl moiety of penicillins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357208"}
{"pmid": "4357209", "title": "Different properties of microsomal UDP-glucuronyltransferase in buffalo rat liver and a clonal strain of rat hepatoma cells derived from the same rat strain.", "content": "Different properties of microsomal UDP-glucuronyltransferase in buffalo rat liver and a clonal strain of rat hepatoma cells derived from the same rat strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357209"}
{"pmid": "4357210", "title": "The Russell-Silver syndrome: a nine-year follow-up.", "content": "The Russell-Silver syndrome: a nine-year follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357210"}
{"pmid": "4357211", "title": "Ménétrier disease and cytomegalovirus infection in childhood.", "content": "Ménétrier disease and cytomegalovirus infection in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357211"}
{"pmid": "4357213", "title": "Letter: Cytomegalovirus infection and toxoplasma.", "content": "Letter: Cytomegalovirus infection and toxoplasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357213"}
{"pmid": "4357212", "title": "Multiple joint dislocations and peculiar facies.", "content": "Multiple joint dislocations and peculiar facies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357212"}
{"pmid": "4357214", "title": "Current concepts in management of periampullary carcinoma.", "content": "Current concepts in management of periampullary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357214"}
{"pmid": "4357215", "title": "Lymphocytes in some hypereosinophilic states.", "content": "Lymphocytes in some hypereosinophilic states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357215"}
{"pmid": "4357216", "title": "Neuromuscular physiology of wound botulism.", "content": "Neuromuscular physiology of wound botulism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357216"}
{"pmid": "4357217", "title": "Unusual complications of iophendylate injection myelography. Report of a case and review.", "content": "Unusual complications of iophendylate injection myelography. Report of a case and review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357217"}
{"pmid": "4357218", "title": "Eye disease among American Indians of the Southwest. II. Trachoma.", "content": "Eye disease among American Indians of the Southwest. II. Trachoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357218"}
{"pmid": "4357220", "title": "Comparison of types 1 and 2 Herpesvirus hominis infection of rabbit eyes. II. Histopathologic and virologic studies.", "content": "Comparison of types 1 and 2 Herpesvirus hominis infection of rabbit eyes. II. Histopathologic and virologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357220"}
{"pmid": "4357219", "title": "Comparison of types 1 and 2 Herpesvirus hominis infection of rabbit eyes. I. Clinical manifestations.", "content": "Comparison of types 1 and 2 Herpesvirus hominis infection of rabbit eyes. I. Clinical manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357219"}
{"pmid": "4357221", "title": "Treatment of neuropathic conditions of the foot and ankle with a patellar-tendon-bearing brace.", "content": "Treatment of neuropathic conditions of the foot and ankle with a patellar-tendon-bearing brace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357221"}
{"pmid": "4357223", "title": "Plasma lipid and lipoprotein abnormalities in patients with malabsorption.", "content": "Plasma lipid and lipoprotein abnormalities in patients with malabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357223"}
{"pmid": "4357224", "title": "Generation of angiotensin II at peripheral vascular level: studies using angiotensin II antisera.", "content": "Generation of angiotensin II at peripheral vascular level: studies using angiotensin II antisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357224"}
{"pmid": "4357222", "title": "Effect of propranolol on cyclic AMP excretion and plasma renin activity in labile essentrial hypertension.", "content": "Effect of propranolol on cyclic AMP excretion and plasma renin activity in labile essentrial hypertension. Labile hypertension is often associated with elevated cardiac output, increased plasma renin activity (PRA) and urinary cyclic AMP excretion in response to upright posture and to isoproterenol. The beta-blocking agent propranolol was demonstrated to be an effective therapeutic agent in this condition. The effect of posture on cyclic AMP, PRA, pulse rate and blood pressure was therefore studied during the administration of propranolol and a placebo in patients with labile hypertension. With the patient on placebo, upright posture induced an increase in pulse rate, cyclic AMP excretion and PRA. Propranolol administration decreased the recumbent and upright blood pressures, pulse rate and PRA. Cyclic AMP excretion remained unchanged in the recumbent position but the postural increase was abolished. No appreciable changes in catecholamine excretion occurred during propranolol administration. Propranolol normalizes some humoral as well as hemodynamic abnormalities of labile hypertension and therefore may be of benefit in long-term treatment and possibly also in the prevention of stable hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357222"}
{"pmid": "4357225", "title": "Effects of midbrain tegmental lesions on sleep and regional brain serotonin and norepinephrine levels in cats.", "content": "Effects of midbrain tegmental lesions on sleep and regional brain serotonin and norepinephrine levels in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357225"}
{"pmid": "4357226", "title": "Glomerular basement membrane antigens of Masugi nephritis.", "content": "Glomerular basement membrane antigens of Masugi nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357226"}
{"pmid": "4357228", "title": "Proceedings: The correlation between redox bioassay and radioimmunoassay for adrenocorticotrophin during insulin hypoglycaemia.", "content": "Proceedings: The correlation between redox bioassay and radioimmunoassay for adrenocorticotrophin during insulin hypoglycaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357228"}
{"pmid": "4357229", "title": "Proceedings: Measurement of plasma adrenocorticotrophin levels in normal and hypopituitary subjects by redox bioassay.", "content": "Proceedings: Measurement of plasma adrenocorticotrophin levels in normal and hypopituitary subjects by redox bioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357229"}
{"pmid": "4357230", "title": "Proceedings: Adrenocorticotrophin (ACTH) and beta-melanocyte-stimulating hormone peptides in tumours associated with the ectopic ACTH syndrome.", "content": "Proceedings: Adrenocorticotrophin (ACTH) and beta-melanocyte-stimulating hormone peptides in tumours associated with the ectopic ACTH syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357230"}
{"pmid": "4357231", "title": "Proceedings: Blueprints for the solution of three endocrinological enigmas. The Sir Henry Dale Lecture for 1973.", "content": "Proceedings: Blueprints for the solution of three endocrinological enigmas. The Sir Henry Dale Lecture for 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357231"}
{"pmid": "4357227", "title": "Pulp reaction to a resin-bonded quartz composite material.", "content": "Pulp reaction to a resin-bonded quartz composite material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357227"}
{"pmid": "4357233", "title": "Proceedings: Calcium dependent release of hypophysiotropic substances from nerve-endings (synaptosomes) isolated from the hypothalamus.", "content": "Proceedings: Calcium dependent release of hypophysiotropic substances from nerve-endings (synaptosomes) isolated from the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357233"}
{"pmid": "4357232", "title": "Proceedings: Effects in vitro of cytoplasmic and nuclear 5alpha-dihydrotestosterone-receptor complexes on prostatic RNA polymerase activities.", "content": "Proceedings: Effects in vitro of cytoplasmic and nuclear 5alpha-dihydrotestosterone-receptor complexes on prostatic RNA polymerase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357232"}
{"pmid": "4357234", "title": "Proceedings: The role of cyclic AMP in the action of androgens on rat ventral prostate gland.", "content": "Proceedings: The role of cyclic AMP in the action of androgens on rat ventral prostate gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357234"}
{"pmid": "4357235", "title": "Proceedings: A comparison of the effects of alpha 1-24 adrenocorticotrophin Zn (Tetracosactrin depot) and of substituted alpha 1-18 adrenocorticotrophin on adrenocortical function in normal subjects.", "content": "Proceedings: A comparison of the effects of alpha 1-24 adrenocorticotrophin Zn (Tetracosactrin depot) and of substituted alpha 1-18 adrenocorticotrophin on adrenocortical function in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357235"}
{"pmid": "4357236", "title": "Proceedings: L-DOPA as a test of anterior pituitary function.", "content": "Proceedings: L-DOPA as a test of anterior pituitary function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357236"}
{"pmid": "4357237", "title": "Proceedings: A simple enzymic method for the radio-iodination of adrenocorticotrophic hormone.", "content": "Proceedings: A simple enzymic method for the radio-iodination of adrenocorticotrophic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357237"}
{"pmid": "4357238", "title": "Proceedings: Effect of protein hormones on the biosynthesis of dehydroepiandrosterone sulphate by human foetal adrenal tissue in vitro.", "content": "Proceedings: Effect of protein hormones on the biosynthesis of dehydroepiandrosterone sulphate by human foetal adrenal tissue in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357238"}
{"pmid": "4357240", "title": "The co-existence of parathyroid and thyroid disease. I. Primary hyperparathyroidism and thyroid carcinoma.", "content": "The co-existence of parathyroid and thyroid disease. I. Primary hyperparathyroidism and thyroid carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357240"}
{"pmid": "4357241", "title": "Angiographic diagnosis of tumors producing hypoglycemia.", "content": "Angiographic diagnosis of tumors producing hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357241"}
{"pmid": "4357242", "title": "Electrical stimulation for relief of pain from chronic nerve injury.", "content": "Electrical stimulation for relief of pain from chronic nerve injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357242"}
{"pmid": "4357243", "title": "Ther reversal of experimental vasospasm by dibutyryl-3',5'-adenosine monophosphate.", "content": "Ther reversal of experimental vasospasm by dibutyryl-3',5'-adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357243"}
{"pmid": "4357246", "title": "Glucagon stimulation of hepatic gluconeogenesis in rats fed a high-protein, carbohydrate-free diet.", "content": "Glucagon stimulation of hepatic gluconeogenesis in rats fed a high-protein, carbohydrate-free diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357246"}
{"pmid": "4357247", "title": "Hormone dependence in breast cancer.", "content": "Hormone dependence in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357247"}
{"pmid": "4357249", "title": "Differences between cytoplasmic glucocorticoid-binding proteins shown by heterogeneity of nuclear acceptor sites.", "content": "Differences between cytoplasmic glucocorticoid-binding proteins shown by heterogeneity of nuclear acceptor sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357249"}
{"pmid": "4357250", "title": "Calcifying mucin producing adenocarcinoma of stomach.", "content": "Calcifying mucin producing adenocarcinoma of stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357250"}
{"pmid": "4357251", "title": "Proceedings: Lichen striatus.", "content": "Proceedings: Lichen striatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357251"}
{"pmid": "4357252", "title": "Computerized axial tomography with the EMI scanner.", "content": "Computerized axial tomography with the EMI scanner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357252"}
{"pmid": "4357253", "title": "Proton radiography in the diagnosis of breast carcinoma.", "content": "Proton radiography in the diagnosis of breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357253"}
{"pmid": "4357254", "title": "Viral infections and the surgical patient.", "content": "Viral infections and the surgical patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357254"}
{"pmid": "4357255", "title": "Surgical experience with malignant tumors of the ampulla of vater and duodenum.", "content": "Surgical experience with malignant tumors of the ampulla of vater and duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357255"}
{"pmid": "4357256", "title": "The significance of mammography, galactography, and pneumocystography in detecting occult carcinomas of the breast.", "content": "The significance of mammography, galactography, and pneumocystography in detecting occult carcinomas of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357256"}
{"pmid": "4357248", "title": "Scar cancer of lung complicating rheumatoid lung disease.", "content": "Scar cancer of lung complicating rheumatoid lung disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357248"}
{"pmid": "4357258", "title": "Letter: Double-blind trial for treatment of herpes iritis and stromal disease.", "content": "Letter: Double-blind trial for treatment of herpes iritis and stromal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357258"}
{"pmid": "4357257", "title": "Induction of ovulation in patients following removal of a pituitary adenoma.", "content": "Induction of ovulation in patients following removal of a pituitary adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357257"}
{"pmid": "4357259", "title": "A comparative quality survey of five common market foods in low and high income economic areas.", "content": "A comparative quality survey of five common market foods in low and high income economic areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357259"}
{"pmid": "4357261", "title": "Dust exposure in the Vermont granite sheds.", "content": "Dust exposure in the Vermont granite sheds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357261"}
{"pmid": "4357260", "title": "Suxamethonium hyperkalaemia in uraemic neuropathy.", "content": "Suxamethonium hyperkalaemia in uraemic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357260"}
{"pmid": "4357263", "title": "Pulmonary function and roentgenographic changes in granite dust exposure.", "content": "Pulmonary function and roentgenographic changes in granite dust exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357263"}
{"pmid": "4357262", "title": "Pulmonary function in granite shed workers of Vermont.", "content": "Pulmonary function in granite shed workers of Vermont.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357262"}
{"pmid": "4357264", "title": "Prostaglandins: their actions on the gastrointestinal tract.", "content": "Prostaglandins: their actions on the gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357264"}
{"pmid": "4357265", "title": "Prostaglandins and the central nervous system.", "content": "Prostaglandins and the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357265"}
{"pmid": "4357266", "title": "Substances that inhibit the actions of prostaglandins.", "content": "Substances that inhibit the actions of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357266"}
{"pmid": "4357267", "title": "Biological aspects of prostaglandins.", "content": "Biological aspects of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357267"}
{"pmid": "4357268", "title": "Prostaglandins in hematology.", "content": "Prostaglandins in hematology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357268"}
{"pmid": "4357270", "title": "Enhanced binding of neuraminidase-treated sheep erythrocytes to human T lymphocytes.", "content": "Enhanced binding of neuraminidase-treated sheep erythrocytes to human T lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357270"}
{"pmid": "4357269", "title": "Effects of cobalt on the renal erythropoietic factor and kidney hydrolase activity in the rat.", "content": "Effects of cobalt on the renal erythropoietic factor and kidney hydrolase activity in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357269"}
{"pmid": "4357271", "title": "A thin-layer gel filtration assay of cytoplasmic oestrogen receptors. A possible screening method for hormone dependent tumours.", "content": "A thin-layer gel filtration assay of cytoplasmic oestrogen receptors. A possible screening method for hormone dependent tumours. A thin-layer gel filtration system for the assay of oestrogen receptors in target organ tissue samples as small as 50 mg is presented and compared with the sucrose gradient centrifugation method. Only specific high-affinity binding of [(3)H]17β-oestradiol to endometrial cytosol has been observed with the thin-layer gel filtration assay, despite the presence of relatively high levels of nonspecific binding components. The system could be adapted to the clinical determination of oestrogen receptor content in biopsy material from mammary and endometrial tumours and would be of value in predicting hormone dependency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357271"}
{"pmid": "4357272", "title": "A study of electron spin resonance spectra of whole blood from normal and tumour bearing patients.", "content": "A study of electron spin resonance spectra of whole blood from normal and tumour bearing patients. Electron spin resonance spectra have been obtained from samples of frozen whole blood or separated blood cells and plasma. Blood samples were obtained from human controls having no diagnosed malignancy and from patients with a variety of benign and malignant tumours.The characteristic spectrum from control blood shows two main lines with g values of 4·2 and 2·049. Several smaller lines can also be observed. The line at g = 2·049 may be due to the copper protein ceruloplasmin. Although no qualitative differences could be found between the spectra from controls and cancer patients, samples from patients with certain types of tumour showed a significant increase in size of the g = 2·049 signal above control values. This was most noticeably the case with Hodgkin's disease and to a lesser extent with cancers of the breast. Squamous cell carcinomata, taken as a group, did not show an elevation in average size of the g = 2·049 signal. In this latter group, however, there were some indications that the effects of chemotherapeutic treatment could be followed during the early stages of such treatment. Examples are given in which onset of treatment with various cytotoxic agents was associated with reduction in size of the g = 2·049 signal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357272"}
{"pmid": "4357273", "title": "Early detection of lung cancer. Clinical conference from the University of Iowa College of Medicine.", "content": "Early detection of lung cancer. Clinical conference from the University of Iowa College of Medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357273"}
{"pmid": "4357274", "title": "Sleep recordings from limbic structures in man.", "content": "Sleep recordings from limbic structures in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357274"}
{"pmid": "4357275", "title": "Effect of volume expansion by hyperosmolar and hyperoncotic solutions under constant infusion of angiotensin II on plasma aldosterone in man and its counterbalance by potassium administration.", "content": "Effect of volume expansion by hyperosmolar and hyperoncotic solutions under constant infusion of angiotensin II on plasma aldosterone in man and its counterbalance by potassium administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357275"}
{"pmid": "4357276", "title": "Male sterility induced by ethanol injection into the vas deferens.", "content": "Male sterility induced by ethanol injection into the vas deferens. At the Johns Hopkins medical institutions in Baltimore, mature male rats were used in an investigation of a simple, nonsurgical technique for achieving sterility.  The technique involved the direct injection of 50 mcl of 95% ethanol directly into the lumen of the vas.  The respective treatments for rat Groups A-F were 1) .9% sodium chloride injected into both vasa, 2) ethanol injected into both vasa, 3) ethanol injected into 1 vas, 4) ligation of both vasa, 5) ligation of 1 vas, and 6) ligation of 1 vas and  ethanol injected into the other vas.  The numbers of animals in the respective groups were 16, 22, 6, 15, 15, and 10.  2 weeks after treatment all of the rats were transferred to individual cages each containing 2 mature females.  At 3 months posttreatment comparisons were made.  In Groups B and F all of the rats were sterile.  In Groups A and C, most of the rats were sterile (12/16 and 5/6, respectively.  Ligations gave expected successes in Group B.  Ethanol acts as a sclerosing agent; the pathological changes are described.  Whether the method provides permanent sterilization is undecided.  Testing with human cadavers has suggested the method is quite feasible for humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357276"}
{"pmid": "4357277", "title": "The menstrual cycle in women treated with d-norgestrel 37.5 micrograms in continuous administration.", "content": "The menstrual cycle in women treated with d-norgestrel 37.5 micrograms in continuous administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357277"}
{"pmid": "4357279", "title": "Demonstration of HL-A antigens, \"species\", and \"semen\"-specific antigens on human spermatozoa. A study by immunofluorescence and immunoelectron microscopy.", "content": "Demonstration of HL-A antigens, \"species\", and \"semen\"-specific antigens on human spermatozoa. A study by immunofluorescence and immunoelectron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357279"}
{"pmid": "4357278", "title": "Occurrence of HL-A antibodies in sera of sterile women.", "content": "Occurrence of HL-A antibodies in sera of sterile women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357278"}
{"pmid": "4357280", "title": "Serious pelvic infections associated with intrauterine contraceptive device.", "content": "Serious pelvic infections associated with intrauterine contraceptive device. A study undertaken to discover whether the incidence and types of intrauterine bacterial growth in IUD users differed from those in nonusers is described.  The study 1)compared the early development of infection in IUD users and nonusers, and 2) looked for a correlation between known serious pelvic infection and IUD use.  Of 235 patients seen for gynecologic examination (131 IUD users and 104 nonusers), 21 users for 6 months or more and 1 user for less than 4 months had foul-smelling leukorrhea, irregular bleeding, or both.  Endometrial cultures were positive in 67% of users, and in 62% of the nonusers.  11 long-term IUD users more than 6 months and 1 nonuser had anaerobic organisms (p less than .01).  Of 31 patients admitted for tubo-ovarian or pelvic abcesses, 17 were IUD users, of whom 9 required hysterectomy.  Earlier recognition of foul-smelling mucoid discharge on the IUD tail, or abnormal bleeding, or both, as a sign of early pelvic infection, followed by removal of the IUD and institution of appropriate antibiotic therapy, might prevent the  more serious sequelae of pelvic inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357280"}
{"pmid": "4357281", "title": "The effect of a continuous low dose progestin on tubal and uterine motility.", "content": "The effect of a continuous low dose progestin on tubal and uterine motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357281"}
{"pmid": "4357282", "title": "Tubal occlusion by electrocoagulation under hysteroscopy. A preliminary report.", "content": "Tubal occlusion by electrocoagulation under hysteroscopy. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357282"}
{"pmid": "4357283", "title": "The correlation of clinical and morphological parameters in induced ovulatory cycles in the human.", "content": "The correlation of clinical and morphological parameters in induced ovulatory cycles in the human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357283"}
{"pmid": "4357284", "title": "Occurrence of spontaneous second pregnancy after delivery of conceptions resulting from ovulation induced by various therapeutic modalities.", "content": "Occurrence of spontaneous second pregnancy after delivery of conceptions resulting from ovulation induced by various therapeutic modalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357284"}
{"pmid": "4357285", "title": "The TCu-300 IUD. A preliminary report.", "content": "The TCu-300 IUD. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357285"}
{"pmid": "4357286", "title": "Efforts to relate spermatozoan motility to fertilizing capacity.", "content": "Efforts to relate spermatozoan motility to fertilizing capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357286"}
{"pmid": "4357288", "title": "Amebiasis in the tropics. (A historical review).", "content": "Amebiasis in the tropics. (A historical review).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357288"}
{"pmid": "4357287", "title": "Hepatitis-associated antigen in chronic liver diseases in Upper-Egypt.", "content": "Hepatitis-associated antigen in chronic liver diseases in Upper-Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357287"}
{"pmid": "4357289", "title": "Plasma renin activity: method of measurement and significance in the diagnosis of hypertension.", "content": "Plasma renin activity: method of measurement and significance in the diagnosis of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357289"}
{"pmid": "4357290", "title": "Tissue culture studies of children's tumours.", "content": "Tissue culture studies of children's tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357290"}
{"pmid": "4357291", "title": "Adrenocortical cell deletion: the role of ACTH.", "content": "Adrenocortical cell deletion: the role of ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357291"}
{"pmid": "4357292", "title": "Binding of radioiodinated human placental lactogen to buffalo corpus luteum in vitro.", "content": "Binding of radioiodinated human placental lactogen to buffalo corpus luteum in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357292"}
{"pmid": "4357293", "title": "Age-dependent differences in the binding of (131-I) LH by rat testis homogenates.", "content": "Age-dependent differences in the binding of (131-I) LH by rat testis homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357293"}
{"pmid": "4357294", "title": "Proceedings: Relation of cyclic AMP to sperm motility.", "content": "Proceedings: Relation of cyclic AMP to sperm motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357294"}
{"pmid": "4357295", "title": "Proceedings: Regulation of steroid secretion in sheep ovarian follicles.", "content": "Proceedings: Regulation of steroid secretion in sheep ovarian follicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357295"}
{"pmid": "4357296", "title": "Proceedings: Oestrogen binding to rabbit blastocysts and its possible role in implantation.", "content": "Proceedings: Oestrogen binding to rabbit blastocysts and its possible role in implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357296"}
{"pmid": "4357297", "title": "Letter: Segmental portal hypertension and islet cell adenoma of the pancreas.", "content": "Letter: Segmental portal hypertension and islet cell adenoma of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357297"}
{"pmid": "4357298", "title": "Acute respiratory illness in an American community. The Tecumseh study.", "content": "Acute respiratory illness in an American community. The Tecumseh study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357298"}
{"pmid": "4357301", "title": "Surgical treatment of lung cancer. Five-year follow-up of 266 patients.", "content": "Surgical treatment of lung cancer. Five-year follow-up of 266 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357301"}
{"pmid": "4357302", "title": "Chemically induced reversion and suppression of methionine-I alleles of Neurospora crassa.", "content": "Chemically induced reversion and suppression of methionine-I alleles of Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357302"}
{"pmid": "4357303", "title": "A yeast strain for visual screening for the two reciprocal products of mitotic crossing over.", "content": "A yeast strain for visual screening for the two reciprocal products of mitotic crossing over.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357303"}
{"pmid": "4357304", "title": "Liver microsomal assays for evaluating the metabolism of environmental mutagens.", "content": "Liver microsomal assays for evaluating the metabolism of environmental mutagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357304"}
{"pmid": "4357305", "title": "Analysis of virus replication in ageing human fibroblast cultures.", "content": "Analysis of virus replication in ageing human fibroblast cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357305"}
{"pmid": "4357306", "title": "Effect of neuraminidase pretreatment on the susceptibility of normal and transformed mammalian cells to bovine enterovirus 261.", "content": "Effect of neuraminidase pretreatment on the susceptibility of normal and transformed mammalian cells to bovine enterovirus 261.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357306"}
{"pmid": "4357307", "title": "Prolactin secretion is specifically inhibited by nickel.", "content": "Prolactin secretion is specifically inhibited by nickel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357307"}
{"pmid": "4357308", "title": "Induction of Epstein-Barr virus-related membrane antigens by 5-iododeoxyuridine in non-producer human lymphoblastoid cells.", "content": "Induction of Epstein-Barr virus-related membrane antigens by 5-iododeoxyuridine in non-producer human lymphoblastoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357308"}
{"pmid": "4357309", "title": "Immunofluorescent antigen associated with Epstein-Barr virus induced by 5-Iododeoxyuridine.", "content": "Immunofluorescent antigen associated with Epstein-Barr virus induced by 5-Iododeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357309"}
{"pmid": "4357310", "title": "Theta alloantigen on mouse and rat fibroblasts.", "content": "Theta alloantigen on mouse and rat fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357310"}
{"pmid": "4357311", "title": "Central corticotropin inhibition by arginine vasotocin in the mouse.", "content": "Central corticotropin inhibition by arginine vasotocin in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357311"}
{"pmid": "4357315", "title": "Localization of nucleoside diphosphatase in the onion root tip.", "content": "Localization of nucleoside diphosphatase in the onion root tip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357315"}
{"pmid": "4357316", "title": "Radiology of genitourinary trauma.", "content": "Radiology of genitourinary trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357316"}
{"pmid": "4357317", "title": "Concomitant infection with Entamoeba histolytica and two Shigella strains.", "content": "Concomitant infection with Entamoeba histolytica and two Shigella strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357317"}
{"pmid": "4357318", "title": "Serological evidence of respiratory syncytial virus infection in sheep.", "content": "Serological evidence of respiratory syncytial virus infection in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357318"}
{"pmid": "4357319", "title": "Biolobical activity of corticotrophin peptides with homo-arginine, lysine or ornithine substituted for arginine in position 8.", "content": "Biolobical activity of corticotrophin peptides with homo-arginine, lysine or ornithine substituted for arginine in position 8.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357319"}
{"pmid": "4357320", "title": "Somatotrophic and corticotrophic functions in primary hypothyroidism before and after thyroxine treatment.", "content": "Somatotrophic and corticotrophic functions in primary hypothyroidism before and after thyroxine treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357320"}
{"pmid": "4357321", "title": "Plasma concentration and protein binding of oestriol and its conjugates in pregnancy.", "content": "Plasma concentration and protein binding of oestriol and its conjugates in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357321"}
{"pmid": "4357326", "title": "Response of mitochondrial enzymes to decreased muscular activity.", "content": "Response of mitochondrial enzymes to decreased muscular activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357326"}
{"pmid": "4357325", "title": "Postmenopausal osteoporosis.", "content": "Postmenopausal osteoporosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357325"}
{"pmid": "4357327", "title": "Adrenal steroid secretion in the rabbit: sodium depletion, angiotensin II, and ACTH.", "content": "Adrenal steroid secretion in the rabbit: sodium depletion, angiotensin II, and ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357327"}
{"pmid": "4357328", "title": "Canine cerebrovascular response to nitroglycerin, acetylcholine, 5-hydroxytryptamine, and angiotensin.", "content": "Canine cerebrovascular response to nitroglycerin, acetylcholine, 5-hydroxytryptamine, and angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357328"}
{"pmid": "4357322", "title": "Streptozotocin treatment of tumor hypoglycemia due to primary livercell carcinoma.", "content": "Streptozotocin treatment of tumor hypoglycemia due to primary livercell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357322"}
{"pmid": "4357329", "title": "Gluconeogenesis in a carnivorous bird (black vulture).", "content": "Gluconeogenesis in a carnivorous bird (black vulture).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357329"}
{"pmid": "4357323", "title": "Morphometric study on the distribution of liver necrosis in experimental murine hepatitis by MHV-3 virus.", "content": "Morphometric study on the distribution of liver necrosis in experimental murine hepatitis by MHV-3 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357323"}
{"pmid": "4357324", "title": "Alteration of enzyme histochemistry in liver cells attacked by human hepatitis virus.", "content": "Alteration of enzyme histochemistry in liver cells attacked by human hepatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357324"}
{"pmid": "4357330", "title": "Gout and its relation to lipid metabolism. I. Serum uric acid, lipid, and lipoprotein levels in gout.", "content": "Gout and its relation to lipid metabolism. I. Serum uric acid, lipid, and lipoprotein levels in gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357330"}
{"pmid": "4357331", "title": "Gout and its relation to lipid metabolism. II. Correlations between uric acid, lipid, and lipoprotein levels in gout.", "content": "Gout and its relation to lipid metabolism. II. Correlations between uric acid, lipid, and lipoprotein levels in gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357331"}
{"pmid": "4357332", "title": "Ultrastructural aspects of lymphoreticular cells in rheumatoid synovium.", "content": "Ultrastructural aspects of lymphoreticular cells in rheumatoid synovium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357332"}
{"pmid": "4357333", "title": "Proceedings: Effect of corticotrophin and oral corticosteroids on nocturnally released growth hormone.", "content": "Proceedings: Effect of corticotrophin and oral corticosteroids on nocturnally released growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357333"}
{"pmid": "4357334", "title": "Proceedings: A re-examination of the hypoglycaemia-induced \"stress\" response of the hypothalamo-pituitary-adrenal axis in patients with rheumatoid arthritis on long-term adrenocorticotrophin (ACTH) therapy.", "content": "Proceedings: A re-examination of the hypoglycaemia-induced \"stress\" response of the hypothalamo-pituitary-adrenal axis in patients with rheumatoid arthritis on long-term adrenocorticotrophin (ACTH) therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357334"}
{"pmid": "4357335", "title": "Value of serum gastrin in the diagnosis of the Zollinger-Ellison syndrome.", "content": "Value of serum gastrin in the diagnosis of the Zollinger-Ellison syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357335"}
{"pmid": "4357336", "title": "Formation of enolpyruvate in the phosphoenolpyruvate carboxytransphosphorylase reaction.", "content": "Formation of enolpyruvate in the phosphoenolpyruvate carboxytransphosphorylase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357336"}
{"pmid": "4357337", "title": "Phosphoenolpyruvate carboxytransphosphorylase. An investigation of the mechanism with 18 O.", "content": "Phosphoenolpyruvate carboxytransphosphorylase. An investigation of the mechanism with 18 O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357337"}
{"pmid": "4357338", "title": "Synthesis and biochemical studies of various 8-substituted derivatives of guanosine 3',5'-cyclic phosphate, inosine 3',5'-cyclic phosphate, and xanthosine 3',5'-cyclic phosphate.", "content": "Synthesis and biochemical studies of various 8-substituted derivatives of guanosine 3',5'-cyclic phosphate, inosine 3',5'-cyclic phosphate, and xanthosine 3',5'-cyclic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357338"}
{"pmid": "4357339", "title": "Structures of oligosaccharides produced by base--borohydride degradation of human ovarian cyst blood group H, Le-b and Le-a active glycoproteins.", "content": "Structures of oligosaccharides produced by base--borohydride degradation of human ovarian cyst blood group H, Le-b and Le-a active glycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357339"}
{"pmid": "4357340", "title": "Lateral diffusion, protein mobility, and phase transitions in Escherichia coli membranes. A spin label study.", "content": "Lateral diffusion, protein mobility, and phase transitions in Escherichia coli membranes. A spin label study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357340"}
{"pmid": "4357341", "title": "Comparative electron cytochemical studies of presynaptic and other neuronal mitochondria.", "content": "Comparative electron cytochemical studies of presynaptic and other neuronal mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357341"}
{"pmid": "4357342", "title": "Prostaglandin as a tool for local control of transmitter release from sympathetic nerves.", "content": "Prostaglandin as a tool for local control of transmitter release from sympathetic nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357342"}
{"pmid": "4357343", "title": "Acetylcholine metabolism and release at the nerve-electroplaque junction.", "content": "Acetylcholine metabolism and release at the nerve-electroplaque junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357343"}
{"pmid": "4357344", "title": "Consequences of denervation on the distribution of the cholinergic (nicotinic) receptor sites from Electrophorus electricus revealed by high resolution autoradiography.", "content": "Consequences of denervation on the distribution of the cholinergic (nicotinic) receptor sites from Electrophorus electricus revealed by high resolution autoradiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357344"}
{"pmid": "4357345", "title": "Role of amino acids and peptides in synaptic transmission.", "content": "Role of amino acids and peptides in synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357345"}
{"pmid": "4357346", "title": "Nervous tissue culture--a model to study action and uptake of putative neurotransmitters such as amino acids.", "content": "Nervous tissue culture--a model to study action and uptake of putative neurotransmitters such as amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357346"}
{"pmid": "4357347", "title": "Genetic factors in the natural history of murine leukemia virus infection: G. H. A. Clowes Memorial Lecture.", "content": "Genetic factors in the natural history of murine leukemia virus infection: G. H. A. Clowes Memorial Lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357347"}
{"pmid": "4357348", "title": "Histochemical studies on nuclease activity and neoplastic transformation in rat liver during diethylnitrosamine carcinogenesis.", "content": "Histochemical studies on nuclease activity and neoplastic transformation in rat liver during diethylnitrosamine carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357348"}
{"pmid": "4357349", "title": "Metastasis in a transplantable mammotrophic pituitary tumor.", "content": "Metastasis in a transplantable mammotrophic pituitary tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357349"}
{"pmid": "4357350", "title": "Nonfibroblastic origin of foreign body sarcomas implicated by histological and electron microscopic studies.", "content": "Nonfibroblastic origin of foreign body sarcomas implicated by histological and electron microscopic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357350"}
{"pmid": "4357351", "title": "Transfer of tumor-specific delayed hypersensitivity in vitro to normal guinea pig peritoneal exudate cells using RNA extracts from sensitized lymphoid tissues.", "content": "Transfer of tumor-specific delayed hypersensitivity in vitro to normal guinea pig peritoneal exudate cells using RNA extracts from sensitized lymphoid tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357351"}
{"pmid": "4357352", "title": "Experimental studies bearing on the question of retrograde spread of Hodgkin's disease via the thoracic duct.", "content": "Experimental studies bearing on the question of retrograde spread of Hodgkin's disease via the thoracic duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357352"}
{"pmid": "4357353", "title": "Surface particles on leukemic lymphocytes in humans.", "content": "Surface particles on leukemic lymphocytes in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357353"}
{"pmid": "4357354", "title": "Effect of arginine on the incorporation of 32P into rat liver and Novikoff hepatoma cytosol proteins.", "content": "Effect of arginine on the incorporation of 32P into rat liver and Novikoff hepatoma cytosol proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357354"}
{"pmid": "4357355", "title": "Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.", "content": "Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357355"}
{"pmid": "4357356", "title": "A study of the macromolecular binding of 67Ga in normal and malignant animal tissues.", "content": "A study of the macromolecular binding of 67Ga in normal and malignant animal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357356"}
{"pmid": "4357357", "title": "Cyclic adenosine 3',5'-monophosphate and cell volume.", "content": "Cyclic adenosine 3',5'-monophosphate and cell volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357357"}
{"pmid": "4357358", "title": "Enhancement of lymphoma cell immunogenicity by infection with nononcogenic virus.", "content": "Enhancement of lymphoma cell immunogenicity by infection with nononcogenic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357358"}
{"pmid": "4357359", "title": "Host age dependency of regression of Rous sarcomas of chickens.", "content": "Host age dependency of regression of Rous sarcomas of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357359"}
{"pmid": "4357360", "title": "Similarity of ribosomal and ribosomal precursor RNA's from rat liver and the Novikoff ascites hepatoma.", "content": "Similarity of ribosomal and ribosomal precursor RNA's from rat liver and the Novikoff ascites hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357360"}
{"pmid": "4357361", "title": "Characterization of primary hepatocellular carcinomas and initial transplant generations.", "content": "Characterization of primary hepatocellular carcinomas and initial transplant generations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357361"}
{"pmid": "4357362", "title": "A survey of blood group, serum protein and red cell enzyme polymorphisms in the Orkney islands.", "content": "A survey of blood group, serum protein and red cell enzyme polymorphisms in the Orkney islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357362"}
{"pmid": "4357365", "title": "Factors determining the site of synthesis of poliovirus proteins: the early attachment of virus particles to endoplasmic membranes.", "content": "Factors determining the site of synthesis of poliovirus proteins: the early attachment of virus particles to endoplasmic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357365"}
{"pmid": "4357366", "title": "A rapidly sedimenting fraction of rat liver endoplasmic reticulum.", "content": "A rapidly sedimenting fraction of rat liver endoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357366"}
{"pmid": "4357367", "title": "Effects of ethidium bromide on growth, chlorophyll synthesis, ultrastructure and mitochondrial DNA in green and bleached mutant, Euglena gracilis.", "content": "Effects of ethidium bromide on growth, chlorophyll synthesis, ultrastructure and mitochondrial DNA in green and bleached mutant, Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357367"}
{"pmid": "4357368", "title": "Ross River virus replication in cultured mosquito and mammalian cells: virus growth and correlated ultrastructural changes.", "content": "Ross River virus replication in cultured mosquito and mammalian cells: virus growth and correlated ultrastructural changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357368"}
{"pmid": "4357369", "title": "The interaction of herpes simplex virus with cultures of peripheral nervous tissue: an electron microscopic study.", "content": "The interaction of herpes simplex virus with cultures of peripheral nervous tissue: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357369"}
{"pmid": "4357370", "title": "Induction of interferon in chick cells by polyoma virus.", "content": "Induction of interferon in chick cells by polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357370"}
{"pmid": "4357371", "title": "Surface antigen on hamster cells transformed in vitro by two strains of Rous sarcoma virus.", "content": "Surface antigen on hamster cells transformed in vitro by two strains of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357371"}
{"pmid": "4357372", "title": "Infection, haemorrhage and death of chick embryos after inoculation of herpes simplex virus type 2 on to the chorioallantoic membrane.", "content": "Infection, haemorrhage and death of chick embryos after inoculation of herpes simplex virus type 2 on to the chorioallantoic membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357372"}
{"pmid": "4357373", "title": "Interferon bioassay: reduction in yield of myxovirus neuraminidases.", "content": "Interferon bioassay: reduction in yield of myxovirus neuraminidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357373"}
{"pmid": "4357375", "title": "Interferon induction site: poly IC on solid substrate carriers.", "content": "Interferon induction site: poly IC on solid substrate carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357375"}
{"pmid": "4357374", "title": "The effect of frog virus 3 on the biological activity of various RNA viruses.", "content": "The effect of frog virus 3 on the biological activity of various RNA viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357374"}
{"pmid": "4357376", "title": "Size differences in the ribonucleic acids of feline leukaemia viruses.", "content": "Size differences in the ribonucleic acids of feline leukaemia viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357376"}
{"pmid": "4357378", "title": "Quantitative studies of oncornaviruses in thin sections.", "content": "Quantitative studies of oncornaviruses in thin sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357378"}
{"pmid": "4357377", "title": "Transfection of chicken fibroblasts with single exposure to DNA from virogenic mammalian cells.", "content": "Transfection of chicken fibroblasts with single exposure to DNA from virogenic mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357377"}
{"pmid": "4357364", "title": "Studies of effects of cyclic adenosine 3',5'-monophosphate in regulation of human hemopoiesis in vitro.", "content": "Studies of effects of cyclic adenosine 3',5'-monophosphate in regulation of human hemopoiesis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357364"}
{"pmid": "4357379", "title": "The formation of poliovirus particles in association with the RNA replication complexes.", "content": "The formation of poliovirus particles in association with the RNA replication complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357379"}
{"pmid": "4357380", "title": "Reflux esophagitis. A comparison of old and new medical management.", "content": "Reflux esophagitis. A comparison of old and new medical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357380"}
{"pmid": "4357381", "title": "Ceruminoma of external ear. A clinico-pathological study of three cases.", "content": "Ceruminoma of external ear. A clinico-pathological study of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357381"}
{"pmid": "4357383", "title": "ATP as a nerve transmitter substance.", "content": "ATP as a nerve transmitter substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357383"}
{"pmid": "4357382", "title": "Initial steps in the de novo pyrimidine biosynthesis in Ascaris suum.", "content": "Initial steps in the de novo pyrimidine biosynthesis in Ascaris suum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357382"}
{"pmid": "4357384", "title": "Chemotaxis, signal relaying and aggregation morphology.", "content": "Chemotaxis, signal relaying and aggregation morphology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357384"}
{"pmid": "4357385", "title": "Sexual maturation in juvenile hypothyroidism.", "content": "Sexual maturation in juvenile hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357385"}
{"pmid": "4357386", "title": "The effect of caffeine on chromosomes of human lymphocytes: a search for the mechanism of action.", "content": "The effect of caffeine on chromosomes of human lymphocytes: a search for the mechanism of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357386"}
{"pmid": "4357387", "title": "5-Methyltryptophan resistance mutations in Escherichia coli K-12. Mutagenic activity of monofunctional alkylating agents including organophosphorus insecticides.", "content": "5-Methyltryptophan resistance mutations in Escherichia coli K-12. Mutagenic activity of monofunctional alkylating agents including organophosphorus insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357387"}
{"pmid": "4357389", "title": "DNA sequence restricted by restriction endonuclease AP from Haemophilus aphirophilus.", "content": "DNA sequence restricted by restriction endonuclease AP from Haemophilus aphirophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357389"}
{"pmid": "4357390", "title": "Human lymphoid cell transformation by Epstein-Barr virus.", "content": "Human lymphoid cell transformation by Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357390"}
{"pmid": "4357388", "title": "Emerging concepts of platelet function.", "content": "Emerging concepts of platelet function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357388"}
{"pmid": "4357391", "title": "Antiviral and non-antiviral activity of highly purified interferon.", "content": "Antiviral and non-antiviral activity of highly purified interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357391"}
{"pmid": "4357392", "title": "Hormone-induced desensitisation of hormonal control of cyclic AMP levels in human diploid fibroblasts.", "content": "Hormone-induced desensitisation of hormonal control of cyclic AMP levels in human diploid fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357392"}
{"pmid": "4357393", "title": "HCG-receptor present in the gonadotrophin insensitive Leydig cell of the immature rat.", "content": "HCG-receptor present in the gonadotrophin insensitive Leydig cell of the immature rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357393"}
{"pmid": "4357363", "title": "Production of Sendai virus for cell fusion.", "content": "Production of Sendai virus for cell fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357363"}
{"pmid": "4357394", "title": "Studies on the active principle of Solanum malacoxylon.", "content": "Studies on the active principle of Solanum malacoxylon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357394"}
{"pmid": "4357396", "title": "Low density lipoproteins of chicken, turkey and quail egg yolk.", "content": "Low density lipoproteins of chicken, turkey and quail egg yolk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357396"}
{"pmid": "4357397", "title": "Effect of temperature on inhibition of chicken liver fructose diphosphatase by adenosine 5'-monophosphate.", "content": "Effect of temperature on inhibition of chicken liver fructose diphosphatase by adenosine 5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357397"}
{"pmid": "4357398", "title": "Toxicity of various selenium derivatives to chick embryos.", "content": "Toxicity of various selenium derivatives to chick embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357398"}
{"pmid": "4357399", "title": "Some physiological responses of turkeys selected for high and low adrenal response to cold stress.", "content": "Some physiological responses of turkeys selected for high and low adrenal response to cold stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357399"}
{"pmid": "4357400", "title": "Reversibility of inhibition of chicken liver fructose diphosphatase by adenosine 5'-monophosphate.", "content": "Reversibility of inhibition of chicken liver fructose diphosphatase by adenosine 5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357400"}
{"pmid": "4357401", "title": "Protocollagen proline hydroxylase activity in human gingiva.", "content": "Protocollagen proline hydroxylase activity in human gingiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357401"}
{"pmid": "4357402", "title": "Skeletal development of Finnish children in the light of hand-wrist roentgenograms.", "content": "Skeletal development of Finnish children in the light of hand-wrist roentgenograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357402"}
{"pmid": "4357403", "title": "Flunitrazepam (Ro 5-4200) and sleep cycle in normal subjects.", "content": "Flunitrazepam (Ro 5-4200) and sleep cycle in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357403"}
{"pmid": "4357404", "title": "Stimulation of cyclic AMP in the isolated perfused rat lung.", "content": "Stimulation of cyclic AMP in the isolated perfused rat lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357404"}
{"pmid": "4357405", "title": "Plumbism: adaptive changes in hepatic and renal metabolism.", "content": "Plumbism: adaptive changes in hepatic and renal metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357405"}
{"pmid": "4357407", "title": "Peripheral nerve regeneration; sudomotor print test with iodine impregnated paper.", "content": "Peripheral nerve regeneration; sudomotor print test with iodine impregnated paper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357407"}
{"pmid": "4357406", "title": "Advanced lung cancer: A clinical trial of radiotherapy plus two drug combination regimens.", "content": "Advanced lung cancer: A clinical trial of radiotherapy plus two drug combination regimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357406"}
{"pmid": "4357408", "title": "Paradoxical bradycardia during REM sleep in periodic catatonia.", "content": "Paradoxical bradycardia during REM sleep in periodic catatonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357408"}
{"pmid": "4357413", "title": "Food zealotry and youth: new dilemmas for professionals.", "content": "Food zealotry and youth: new dilemmas for professionals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357413"}
{"pmid": "4357414", "title": "Development of an abortion service in a large municipal hospital. Review of the first year's experience.", "content": "Development of an abortion service in a large municipal hospital. Review of the first year's experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357414"}
{"pmid": "4357415", "title": "Editorial views: Non-respiratory functions of the lung.", "content": "Editorial views: Non-respiratory functions of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357415"}
{"pmid": "4357416", "title": "Anterior displacement of the inferior vena cava by hepatic masses.", "content": "Anterior displacement of the inferior vena cava by hepatic masses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357416"}
{"pmid": "4357421", "title": "Measurement of the oxidation reduction potential of the EPR detectable active centre of the molybdenum iron protein of Chromatium nitrogenase.", "content": "Measurement of the oxidation reduction potential of the EPR detectable active centre of the molybdenum iron protein of Chromatium nitrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357421"}
{"pmid": "4357422", "title": "Genetic regulation of a constitutive operon in E. coli B-r.", "content": "Genetic regulation of a constitutive operon in E. coli B-r.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357422"}
{"pmid": "4357423", "title": "Polyamines and tumor cells: effect of transformation of chick embryo fibroblasts by Rous sarcoma virus on polyamine levels.", "content": "Polyamines and tumor cells: effect of transformation of chick embryo fibroblasts by Rous sarcoma virus on polyamine levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357423"}
{"pmid": "4357424", "title": "Effect of thyroid hormone analogues on the displacement of 125I-L-triiodothyronine from hepatic and heart nuclei in vivo: possible relationship to hormonal activity.", "content": "Effect of thyroid hormone analogues on the displacement of 125I-L-triiodothyronine from hepatic and heart nuclei in vivo: possible relationship to hormonal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357424"}
{"pmid": "4357418", "title": "Diagnosis of tracheal tumors.", "content": "Diagnosis of tracheal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357418"}
{"pmid": "4357425", "title": "Dietary control of stearyl CoA and alkylacylglycerophosphorylethanolamine desaturases in tumor.", "content": "Dietary control of stearyl CoA and alkylacylglycerophosphorylethanolamine desaturases in tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357425"}
{"pmid": "4357420", "title": "Central vestibular diagnosis. Neurologic examination.", "content": "Central vestibular diagnosis. Neurologic examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357420"}
{"pmid": "4357426", "title": "Levels of cyclic AMP in murine L5178Y lymphoblasts grown in different concentrations of serum.", "content": "Levels of cyclic AMP in murine L5178Y lymphoblasts grown in different concentrations of serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357426"}
{"pmid": "4357419", "title": "The ocular fixation index.", "content": "The ocular fixation index.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357419"}
{"pmid": "4357417", "title": "Granular cell myoblastoma of the esophagus. Incidence and surgical treatment.", "content": "Granular cell myoblastoma of the esophagus. Incidence and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357417"}
{"pmid": "4357428", "title": "The molecular weight determination of proteins and glycoproteins of RNA enveloped viruses by polyacrylamide gel electrophoresis in SDS.", "content": "The molecular weight determination of proteins and glycoproteins of RNA enveloped viruses by polyacrylamide gel electrophoresis in SDS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357428"}
{"pmid": "4357429", "title": "Cation-dependent light-induced structural changes in visual receptor membranes.", "content": "Cation-dependent light-induced structural changes in visual receptor membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357429"}
{"pmid": "4357427", "title": "Regulation by beta-adrenergic receptor and muscarinic cholinergic receptor activation of intracellular cyclic AMP and cyclic GMP levels in rat lung slices.", "content": "Regulation by beta-adrenergic receptor and muscarinic cholinergic receptor activation of intracellular cyclic AMP and cyclic GMP levels in rat lung slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357427"}
{"pmid": "4357430", "title": "Biosynthesis and characterization of a phosphatidic acid analog containing beta-hydroxy fatty acid.", "content": "Biosynthesis and characterization of a phosphatidic acid analog containing beta-hydroxy fatty acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357430"}
{"pmid": "4357431", "title": "On the control mechanism of bacterial growth by cyclic adenosine 3',5'-monophosphate.", "content": "On the control mechanism of bacterial growth by cyclic adenosine 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357431"}
{"pmid": "4357432", "title": "Promotion of conidia aggregation in Aspergillus niger by cyclic AMP and 5'-GMP.", "content": "Promotion of conidia aggregation in Aspergillus niger by cyclic AMP and 5'-GMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357432"}
{"pmid": "4357433", "title": "The in vivo effect of indomethacin and prostaglandin E2 on ACTH and DBCAMP-induced steroidogenesis in hypophysectomized rats.", "content": "The in vivo effect of indomethacin and prostaglandin E2 on ACTH and DBCAMP-induced steroidogenesis in hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357433"}
{"pmid": "4357434", "title": "Activity of tubercidin-, toyocomycin-, and sangivamycin-3',5'-cyclic phosphates and related compounds with some enzymes of adenosine-3',5'-cyclic phosphate metabolism.", "content": "Activity of tubercidin-, toyocomycin-, and sangivamycin-3',5'-cyclic phosphates and related compounds with some enzymes of adenosine-3',5'-cyclic phosphate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357434"}
{"pmid": "4357435", "title": "Testosterone binding in the chick oviduct.", "content": "Testosterone binding in the chick oviduct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357435"}
{"pmid": "4357436", "title": "3-Hydroxybenzoate 6-hydroxylase from Pseudomonas aeruginosa.", "content": "3-Hydroxybenzoate 6-hydroxylase from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357436"}
{"pmid": "4357437", "title": "New ATP incorporating activities from rat liver mitochondria: the attachment of a portion of ATP to a pronase-sensitive receptor.", "content": "New ATP incorporating activities from rat liver mitochondria: the attachment of a portion of ATP to a pronase-sensitive receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357437"}
{"pmid": "4357438", "title": "Triacylglycerol secretion in very low density lipoproteins by isolated rat liver parenchymal cells.", "content": "Triacylglycerol secretion in very low density lipoproteins by isolated rat liver parenchymal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357438"}
{"pmid": "4357439", "title": "Cholesterol in mycoplasma membranes. Composition, ultrastructure and biological properties of membranes from Mycoplasma mycoides var. capri cells adapted to grow with low cholesterol concentrations.", "content": "Cholesterol in mycoplasma membranes. Composition, ultrastructure and biological properties of membranes from Mycoplasma mycoides var. capri cells adapted to grow with low cholesterol concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357439"}
{"pmid": "4357440", "title": "Cholesterol in mycoplasma membranes. Correlation of enzymic and transport activities with physical state of lipids in membranes of Mycoplasma mycoides var. capri adapted to grow with low cholesterol concentrations.", "content": "Cholesterol in mycoplasma membranes. Correlation of enzymic and transport activities with physical state of lipids in membranes of Mycoplasma mycoides var. capri adapted to grow with low cholesterol concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357440"}
{"pmid": "4357441", "title": "The adverse effects of drugs on the kidney.", "content": "The adverse effects of drugs on the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357441"}
{"pmid": "4357442", "title": "Alternatives to institutional care.", "content": "Alternatives to institutional care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357442"}
{"pmid": "4357443", "title": "Psychogeriatrics.", "content": "Psychogeriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357443"}
{"pmid": "4357444", "title": "Auditory discrimination during REM and non-REM sleep in women before and after delivery.", "content": "Auditory discrimination during REM and non-REM sleep in women before and after delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357444"}
{"pmid": "4357446", "title": "There's more than cancer on the brain. Nuclear medicine and the diagnosis of nonneoplastic pediatric brain lesions (or abscess, blood vessel anomaly, or clot?).", "content": "There's more than cancer on the brain. Nuclear medicine and the diagnosis of nonneoplastic pediatric brain lesions (or abscess, blood vessel anomaly, or clot?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357446"}
{"pmid": "4357448", "title": "Effect of prostaglandin E1 on cholesterol biosynthesis in rat liver.", "content": "Effect of prostaglandin E1 on cholesterol biosynthesis in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357448"}
{"pmid": "4357449", "title": "Prolonged elevation of plasma cortisol levels in dogs treated with an 18 amino acid synthetic corticotrophin.", "content": "Prolonged elevation of plasma cortisol levels in dogs treated with an 18 amino acid synthetic corticotrophin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357449"}
{"pmid": "4357450", "title": "5-HT hyperpolarization of bullfrog sympathetic ganglion cell membrane.", "content": "5-HT hyperpolarization of bullfrog sympathetic ganglion cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357450"}
{"pmid": "4357451", "title": "Immunochemical relationships among lysosomal acid phosphohydrolases: DNase II and nonspecific phosphodiesterase.", "content": "Immunochemical relationships among lysosomal acid phosphohydrolases: DNase II and nonspecific phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357451"}
{"pmid": "4357453", "title": "Electron-nuclear double resonance study of flavodoxin from Peptostreptococcus elsdenii.", "content": "Electron-nuclear double resonance study of flavodoxin from Peptostreptococcus elsdenii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357453"}
{"pmid": "4357454", "title": "Amoebicidal action of bile salts and other surface-active agents on axenically grown Entamoeba histolytica.", "content": "Amoebicidal action of bile salts and other surface-active agents on axenically grown Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357454"}
{"pmid": "4357455", "title": "Periphal vascular disease in diabetes mellitus.", "content": "Periphal vascular disease in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357455"}
{"pmid": "4357456", "title": "Paralytic poliomyelitis: clinical and virological studies.", "content": "Paralytic poliomyelitis: clinical and virological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357456"}
{"pmid": "4357458", "title": "Activation of Na-K activated ATPase in rat brain by catecholamine.", "content": "Activation of Na-K activated ATPase in rat brain by catecholamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357458"}
{"pmid": "4357459", "title": "A scanning electron microscope study of surface features of viral and spontaneous transformants of mouse Balb-3T3 cells.", "content": "A scanning electron microscope study of surface features of viral and spontaneous transformants of mouse Balb-3T3 cells. Cells of the mouse line Balb/3T3 as well as three virus-induced transformants and two spontaneous transformants grown in vitro have been studied for their topography by scanning electron microscopy. The parent cell in confluent culture closely resembles an endothelial cell in its form and in the structure of its association with adjacent cells. The tumorigenic transformants produced by SV40, murine sarcoma virus, or polyoma viruses are fusiform to pleomorphic and distinctly different from the cell of origin. They show relatively smooth surfaces except for blebs and marginal microvilli. Perhaps most surprising is the similarity they bear to one another. This is made the more singular by the very different form shown by the tumorigenic transformants of spontaneous origin. One of these, S2-4, possesses a thickened rather than the lamellar form of the parent A31 cell and is covered by long microvilli and many spherical blebs. The other, TuT(3), more closely resembles the cell of origin but shows extensive ruffling at its margins. All transformants grow without evidence of contact inhibition. The significance of the surface morphologies and the factors influencing cell form are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357459"}
{"pmid": "4357461", "title": "Parenchymal cells from adult rat liver in nonproliferating monolayer culture. II. Ultrastructural studies.", "content": "Parenchymal cells from adult rat liver in nonproliferating monolayer culture. II. Ultrastructural studies. Hepatic parenchymal cells from adult rats, established in vitro as a monolayer, have been evaluated by electron microscopy. Within 24 h after the initial seeding, the incubated cells were polygonal and in close apposition with three to six neighboring cells. The ultrastructure of the monolayer cells was examined at this time and after 3 and 10 days of incubation. With the exception of a few enlarged mitochondria, organelles in both the 1- and 3-day monolayer cells were indistinguishable quantitatively and morphologically from those found in the intact liver. After 10 days of incubation, however, the rough-surfaced endoplasmic reticulum (RER) had become dilated and vesiculated. In all cells studied, portions of RER were found in a close spatial relationship to mitochondria. From its frequency, this association appeared to be more than fortuitous, and the organelle complex may represent a functional unit necessary for new membrane formation, as suggested previously. The Golgi complexes of 1- and 3-day cells contained very low density lipoprotein-sized particles, which suggests that the monolayer cells synthesize lipoproteins. These electron microscope observations demonstrate that adult hepatic parenchymal cells in monolayer retain for several days the subcellular structural elements characteristic of normally functioning hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357461"}
{"pmid": "4357462", "title": "Insulin binding to rat liver Golgi fractions.", "content": "Insulin binding to rat liver Golgi fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357462"}
{"pmid": "4357463", "title": "Cytochemical identification of phosphatase activity in the contractile vacuole of Acanthamoeba castellanii.", "content": "Cytochemical identification of phosphatase activity in the contractile vacuole of Acanthamoeba castellanii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357463"}
{"pmid": "4357464", "title": "Lesions of the breast.", "content": "Lesions of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357464"}
{"pmid": "4357466", "title": "The sulcular epithelium as a reservoir for herpes simplex virus in man.", "content": "The sulcular epithelium as a reservoir for herpes simplex virus in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357466"}
{"pmid": "4357465", "title": "Production of cyclic AMP and adenosine by the brain and prothoracic glands of Manduca sexta.", "content": "Production of cyclic AMP and adenosine by the brain and prothoracic glands of Manduca sexta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357465"}
{"pmid": "4357460", "title": "Parenchymal cells from adult rat liver in nonproliferating monolayer culture. I. Functional studies.", "content": "Parenchymal cells from adult rat liver in nonproliferating monolayer culture. I. Functional studies. Parenchymal cells from adult rat liver have been established in primary monolayer culture. Donor animals are subjected to a partial hepatectomy and, 4 days later, cells are prepared by collagenase perfusion of the regenerated liver. The hepatic parenchymal cells, separated from nonparenchymal material and suspended in serum-free medium, are placed in plastic tissue culture dishes, where they form a monolayer within 24 h. The monolayer cells exhibit minimal mitotic activity and demonstrate several major metabolic functions characteristic of liver in vivo; these include albumin synthesis and secretion, gluconeogenesis from 3-carbon precursors, responsiveness to insulin and glucagon, glycogen synthesis, and activity of two microsomal enzymes. These functions are present in the monolayer cells for several days at activities similar to those observed in the liver in vivo. The findings indicate that hepatic parenchymal cells in this monolayer system are viable and behave in many respects like normal adult rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357460"}
{"pmid": "4357471", "title": "Effects of adrenaline, noradrenaline and isoprenaline on the electrical and mechanical responses of the guinea-pig vas deferens to nerve stimulation.", "content": "Effects of adrenaline, noradrenaline and isoprenaline on the electrical and mechanical responses of the guinea-pig vas deferens to nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357471"}
{"pmid": "4357472", "title": "Effects of acetylcholine and some other smooth muscle stimulants on the electrical and mechanical responses of the guinea-pig vas deferens to nerve stimulation.", "content": "Effects of acetylcholine and some other smooth muscle stimulants on the electrical and mechanical responses of the guinea-pig vas deferens to nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357472"}
{"pmid": "4357474", "title": "Lipid and fatty acid modifications in plasma lipoproteins of baboons under atherogenic diet.", "content": "Lipid and fatty acid modifications in plasma lipoproteins of baboons under atherogenic diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357474"}
{"pmid": "4357475", "title": "Marmota monax: a model for studies of cardiovascular, cerebrovascular and neoplastic disease.", "content": "Marmota monax: a model for studies of cardiovascular, cerebrovascular and neoplastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357475"}
{"pmid": "4357476", "title": "The susceptibility and response of wild waterfowl to duck plague virus.", "content": "The susceptibility and response of wild waterfowl to duck plague virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357476"}
{"pmid": "4357479", "title": "Anaesthesia, surgery and renal function: immediate and delayed effects.", "content": "Anaesthesia, surgery and renal function: immediate and delayed effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357479"}
{"pmid": "4357478", "title": "Auscultation of the abdomen with reference to vascular sounds.", "content": "Auscultation of the abdomen with reference to vascular sounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357478"}
{"pmid": "4357477", "title": "Studies of human amebiasis. 3. Ameboma: a radiologic manifestation of amebic colitis.", "content": "Studies of human amebiasis. 3. Ameboma: a radiologic manifestation of amebic colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357477"}
{"pmid": "4357481", "title": "Effect of ethanol administration on cyclic 3',5'-adenosine monophosphate metabolism in brain.", "content": "Effect of ethanol administration on cyclic 3',5'-adenosine monophosphate metabolism in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357481"}
{"pmid": "4357480", "title": "Substrate specificity of caeruloplasmin indoles and indole isosteres.", "content": "Substrate specificity of caeruloplasmin indoles and indole isosteres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357480"}
{"pmid": "4357482", "title": "Artifactual subcellular distribution of dopamine beta-hydroxylase. Effects of dilution and non-specific protein on the dopamine beta-hydroxylase activity of membranes of adrenomedullary and sympathetic nerve vesicles.", "content": "Artifactual subcellular distribution of dopamine beta-hydroxylase. Effects of dilution and non-specific protein on the dopamine beta-hydroxylase activity of membranes of adrenomedullary and sympathetic nerve vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357482"}
{"pmid": "4357483", "title": "Response of isolated white fat cells to anti-malarial drugs.", "content": "Response of isolated white fat cells to anti-malarial drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357483"}
{"pmid": "4357485", "title": "Bone sodium exchange. Effect of rachitism and vitamin D3 treatment on chicks.", "content": "Bone sodium exchange. Effect of rachitism and vitamin D3 treatment on chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357485"}
{"pmid": "4357486", "title": "A simplified competitive protein-binding assay for adenosine 3',5'-monophosphate in plasma.", "content": "A simplified competitive protein-binding assay for adenosine 3',5'-monophosphate in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357486"}
{"pmid": "4357487", "title": "Determination of di-(2-ethylhexyl)-phthalate (DEHP) in human plasma.", "content": "Determination of di-(2-ethylhexyl)-phthalate (DEHP) in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357487"}
{"pmid": "4357488", "title": "Catecholamines and vasomotion.", "content": "Catecholamines and vasomotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357488"}
{"pmid": "4357489", "title": "Carbon tetrachloride hepatotoxicity: an example of lethal cleavage.", "content": "Carbon tetrachloride hepatotoxicity: an example of lethal cleavage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357489"}
{"pmid": "4357490", "title": "Peripheral neuropathy caused by chemical agents.", "content": "Peripheral neuropathy caused by chemical agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357490"}
{"pmid": "4357491", "title": "Vertebrobasilar aneurysms. Experience with 27 cases.", "content": "Vertebrobasilar aneurysms. Experience with 27 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357491"}
{"pmid": "4357492", "title": "Limitations of deteriorated tissue for rabies diagnosis.", "content": "Limitations of deteriorated tissue for rabies diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357492"}
{"pmid": "4357493", "title": "Occurrence of canine adenovirus antibodies and non-specific inhibitors of haemagglutination in the sera of diverse animal species.", "content": "Occurrence of canine adenovirus antibodies and non-specific inhibitors of haemagglutination in the sera of diverse animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357493"}
{"pmid": "4357494", "title": "Effect on calves of the intravenous injection of the enterotoxin of Clostridium welchii type A.", "content": "Effect on calves of the intravenous injection of the enterotoxin of Clostridium welchii type A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357494"}
{"pmid": "4357495", "title": "Radioimmunoassay of plasma adrenocorticotrophin in Cushing's syndrome.", "content": "Radioimmunoassay of plasma adrenocorticotrophin in Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357495"}
{"pmid": "4357498", "title": "Influence of testosterone and cyproterone acetate on the rate of mitosis in seminal vesicles of rats.", "content": "Influence of testosterone and cyproterone acetate on the rate of mitosis in seminal vesicles of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357498"}
{"pmid": "4357496", "title": "Circadian periodicity of pituitary-adrenal function after p-chlorophenylalanine administration in the rat.", "content": "Circadian periodicity of pituitary-adrenal function after p-chlorophenylalanine administration in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357496"}
{"pmid": "4357497", "title": "Effect of hypothalamic releasing factors and steroids on release of gonadotrophins by organ cultures of human foetal pituitaries.", "content": "Effect of hypothalamic releasing factors and steroids on release of gonadotrophins by organ cultures of human foetal pituitaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357497"}
{"pmid": "4357499", "title": "Enzymic activities and sodium, potassium and copper concentrations in mouse brain and liver after cuprizone treatment in vivo.", "content": "Enzymic activities and sodium, potassium and copper concentrations in mouse brain and liver after cuprizone treatment in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357499"}
{"pmid": "4357500", "title": "Activity of cyclic AMP-dependent microsomal protein kinase and phosphorylation of ribosomal protein in rat brain during postnatal development.", "content": "Activity of cyclic AMP-dependent microsomal protein kinase and phosphorylation of ribosomal protein in rat brain during postnatal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357500"}
{"pmid": "4357501", "title": "Effect of hyperphenylalaninemia on fatty acid composition of lipids of rat brain myelin.", "content": "Effect of hyperphenylalaninemia on fatty acid composition of lipids of rat brain myelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357501"}
{"pmid": "4357502", "title": "Postsynaptic adrenergic-cyclic AMP control of the serotonin content of cultured rat pineal glands.", "content": "Postsynaptic adrenergic-cyclic AMP control of the serotonin content of cultured rat pineal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357502"}
{"pmid": "4357503", "title": "Acummulation of cyclic adenosine 3', 5'-monophosphate in cerebral cortical slices from rat and mouse: stimulatory effect of alpha- and beta-adrenergic agents and adenosine.", "content": "Acummulation of cyclic adenosine 3', 5'-monophosphate in cerebral cortical slices from rat and mouse: stimulatory effect of alpha- and beta-adrenergic agents and adenosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357503"}
{"pmid": "4357504", "title": "Some aspects of visual physiology of the honeybee.", "content": "Some aspects of visual physiology of the honeybee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357504"}
{"pmid": "4357505", "title": "Small RNAs of Rous sarcoma virus: characterization by two-dimensional polyacrylamide gel electrophoresis and fingerprint analysis.", "content": "Small RNAs of Rous sarcoma virus: characterization by two-dimensional polyacrylamide gel electrophoresis and fingerprint analysis. Approximately 15 to 20 different species of small (4 to 7S) RNAs have been purified by two-dimensional polyacrylamide gel electrophoresis of RNA isolated from virions of Schmidt-Ruppin D strain of Rous sarcoma virus. Each species of small RNA has been isolated free of 70S RNA; nine of them, including 5S and 7S RNAs, were also found associated with the 70S genomic RNA. Most of the 4S RNAs are present at an average of less than one copy per virion. The 4S RNAs have T1 RNase (EC 2.7.7.26) fingerprints, which are very similar to those of tRNAs. One of the smallest 4S RNAs, which can act as a primer for initiation of RNA-directed DNA synthesis, is associated with the 70S RNA in 1 to 2 copies per complex, whereas an additional 6 to 8 copies of this molecule are free.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357505"}
{"pmid": "4357506", "title": "Primary in vivo transcription of vesicular stomatitis virus and temperature-sensitive mutants of five vesicular stomatitis virus complementation groups.", "content": "Primary in vivo transcription of vesicular stomatitis virus and temperature-sensitive mutants of five vesicular stomatitis virus complementation groups. The process of adsorption and RNA transcription by vesicular stomatitis virus (VSV) in cells has been followed by using highly labeled preparations of VSV virions. The initial transcription process (primary parental transcription) is rapid and takes about 4 min to develop complete transcripts of the input genome. The optimal cell temperature for in vivo transcription is between 36 and 39.5 C, although transcription can be detected at 18 C. No negative effect on primary parental transcription was obtained by the presence of actinomycin D, puromycin, or cycloheximide. Demonstrable primary transcription by selected temperature-sensitive mutants of all five complementation groups of VSV was obtained at either 31 and 34 C (permissive temperatures for virus production) or 39.5 C (nonpermissive temperature for virus development). VSV grown in hamster (BHK 21) or chicken embryo cells were more efficiently adsorbed and transcribed in BHK cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357506"}
{"pmid": "4357507", "title": "Analysis of minimal functions of simian virus 40. II. Enhancement of oncogenic transformation in vitro by UV irradiation.", "content": "Analysis of minimal functions of simian virus 40. II. Enhancement of oncogenic transformation in vitro by UV irradiation. After light UV irradiation (5,000 to 10,000 ergs/mm(2)) \"complete\" and \"defective\" simian virus 40 (SV40) showed an enhancement of oncogenic transformation capacity in Syrian hamster kidney cells in vitro up to 180 and 270% of the controls, respectively. Simultaneously with the enhancement of transformation, an increase in T-antigen induction was observed in CV-1 cells infected with light UV-irradiated SV40; infectivity, however, was correspondingly reduced by 1 log(10). After strong UV irradiation (10,000 to 80,000 ergs/mm(2)) of \"complete\" and \"defective\" SV40, transformation capacity in vitro proved to be the most resistant viral function. It was only slightly reduced in comparison with a 4 to 5 log(10) reduction of infectivity. T-antigen induction of SV40 was also equally resistant to strong UV irradiation. We found no evidence of \"multiplicity reactivation\" involved in the high resistance of transformation capacity of SV40 after UV irradiation. Syrian hamster kidney cells transformed in vitro by UV-irradiated SV40 contained the SV40-specific T-antigen and showed the same morphology and growth characteristics as cells transformed by non-irradiated \"complete\" or \"defective\" SV40. They induced malignant tumors after subcutaneous inoculation into Syrian hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357507"}
{"pmid": "4357508", "title": "Restricted replication of vesicular stomatitis virus in human lymphoblastoid cells.", "content": "Restricted replication of vesicular stomatitis virus in human lymphoblastoid cells. Replication of vesicular stomatitis virus (VSV) is restricted in one human lymphoblastoid cell line (Raji), but not in another similar cell line (Wil-2), compared with growth in HeLa cells. This restriction is characterized by a low proportion of cells yielding infectious virus and is associated with limited production of 42S virion RNA. Primary transcription of 13S and 26S VSV-specific RNA is not restricted in Raji cells, and the 13S RNA produced contains adenylate-rich sequences. This suggests that the block in Raji cells involves some step required for the replication of virion RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357508"}
{"pmid": "4357510", "title": "L protein requirement for in vitro RNA synthesis by vesicular stomatitis virus.", "content": "L protein requirement for in vitro RNA synthesis by vesicular stomatitis virus. The endogenous transcriptase present in purified vesicular stomatitis (VS) virions was solubilized with a Triton X-100 high-salt solution. The polymerase activity was purified on glycerol gradients and by phosphocellulose column chromatography; the viral proteins present in the active enzyme fractions were identified by sodium dodecyl sulfate polyacrylamide gel electrophoresis. It was demonstrated that L protein, but not NS protein, was required for in vitro RNA synthesis on the VS viral nucleocapsid template. Solubilized L protein rebinds to the ribonucleoprotein template when the transcription complex is reconstituted, and the RNA synthesized in vitro by purified L protein hybridizes to virion RNA. Cyanogen bromide peptide fingerprints indicate that the large L protein is a unique polypeptide chain. It is concluded that the L protein functions as the transcriptase, and the nucleocapsid NS protein is not essential for in vitro RNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357510"}
{"pmid": "4357509", "title": "Cleavage of circular, superhelical simian virus 40 DNA to a linear duplex by S1 nuclease.", "content": "Cleavage of circular, superhelical simian virus 40 DNA to a linear duplex by S1 nuclease. S(1) nuclease, the single-strand specific nuclease from Aspergillus oryzae can cleave both strands of circular covalently closed, superhelical simian virus 40 (SV40) DNA to generate unit length linear duplex molecules with intact single strands. But circular, covalently closed, nonsuperhelical DNA, as well as linear duplex molecules, are relatively resistant to attack by the enzyme. These findings indicate that unpaired or weakly hydrogen-bonded regions, sensitive to the single strand-specific nuclease, occur or can be induced in superhelical DNA. Nicked, circular SV40 DNA can be cleaved on the opposite strand at or near the nick to yield linear molecules. S(1) nuclease may be a useful reagent for cleaving DNAs at regions containing single-strand nicks. Unlike the restriction endonucleases, S(1) nuclease probably does not cleave SV40 DNA at a specific nucleotide sequence. Rather, the sites of cleavage occur within regions that are readily denaturable in a topologically constrained superhelical molecule. At moderate salt concentrations (75 mM) SV40 DNA is cleaved once, most often within either one of the two following regions: the segments defined as 0.15 to 0.25 and 0.45 to 0.55 SV40 fractional length, clockwise, from the EcoR(I) restriction endonuclease cleavage site (defined as the zero position on the SV40 DNA map). In higher salt (250 mM) cleavage occurs preferentially within the 0.45 to 0.55 segment of the map.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357509"}
{"pmid": "4357511", "title": "Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell.", "content": "Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell. Analyses of polypeptides made in HEp-2 cells infected with herpes simplex virus type 1 by high-resolution polyacrylamide gel electrophoresis revealed the synthesis of at least 49 infected cell polypeptides (ICP) ranging in molecular weight from 15,000 to 280,000. Evidence for virus specificity based on increased rates of synthesis postinfection, immunological specificity, and viral control of mobility and rate of synthesis was available for 47 of the ICP. These 47 polypeptides can account for 75% of the virus genetic information assuming a DNA molecular weight of 10(8) and asymmetric transcription. On the basis of their mobility relative to virion proteins, the ICP were classified as structural (S, 23 polypeptides), nonstructural (NS, 16 polypeptides), and unassigned (U, 10 polypeptides). Analysis of the synthesis of the ICP revealed the following. (i) Rapid posttranslational cleavages of HSV proteins were not detected; in parallel experiments rapid posttranslational cleavages were readily demonstrated in poliovirus-infected cells and these were blocked by protease inhibitors. (ii) Slow posttranslational changes in the mobility of at least two polypeptides were observed. (iii) Analysis of the rates of synthesis of ICP examined at four intervals postinfection revealed regulation of the pattern and amount of ICP synthesized. ICP formed six classes (A to F) differing in their kinetics of synthesis. S and NS ICP were distributed nonrandomly among these classes. Thus, of the sum of S protein amino acid sequences apportioned among these kinetic classes, 47%, constituting class A and comprising \"late\" structural proteins, were characterized by progressively increasing rates of synthesis until at least 12 h postinfection; whereas \"early\" structural proteins constituting class C, amounting to 31% of the total amino acid sequences, were synthesized with initially increasing rates until 4 h postinfection and with declining rates thereafter. NS polypeptides and remaining S polypeptides were distributed among the other kinetic classes-B, D, E, and F. Control of protein abundance was evident in that the polypeptides were not made in equimolar amounts. However, S and NS polypeptides could not be differentiated on the basis of their molar rates of synthesis. The bulk of the detected polypeptides did not differ by more than eightfold in their molar rates of synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357511"}
{"pmid": "4357512", "title": "RNA synthesis of vesicular stomatitis virus. V. Interactions between transcription and replication.", "content": "RNA synthesis of vesicular stomatitis virus. V. Interactions between transcription and replication. The temperature-sensitive mutant ts114 of vesicular stomatitis virus is temperature-sensitive in both primary and secondary transcription, but not in the replication of 40S RNA. The synthesis of 40S RNA is specifically inhibited when protein synthesis is shut off. The addition of cycloheximide to cells infected by ts114, rapidly inhibits RNA replication at the permissive and nonpermissive temperatures. However, the addition of cycloheximide at the nonpermissive temperature also results in almost complete recovery of transcription to the level found at the permissive temperature. Other inhibitors of protein synthesis applied at the nonpermissive temperature result in the same recoverability of the apparent temperature-sensitive lesion. Ribonucleic acid products synthesized by ts114 at the nonpermissive temperature in the presence of cycloheximide are identical to virus-specific messenger RNA by the criteria of size and complementarity to virion RNA. When mutant-infected cells are shifted to the nonpermissive temperature, incubated for a period of time, and then treated with cycloheximide, the ratio of transcriptive to replicative activity varies depending on the time at which radioactive precursor is added to cells. This suggests an interdependence between replication and transcription during virus-specific RNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357512"}
{"pmid": "4357514", "title": "Defective interfering particles of poliovirus. IV. Mechanisms of enrichment.", "content": "Defective interfering particles of poliovirus. IV. Mechanisms of enrichment. Infection of HeLa cells by mixtures of standard poliovirus and defective, interfering (DI) poliovirus particles leads to a higher ratio of DI particles in the progeny than in the inoculum. The extent of this enrichment could be varied by various manipulations of the co-infected cells. At any time during the infection cycle, virions made within short times after addition of radioactive uridine were hyperenriched in DI particles; this transient hyperenrichment fell to the equilibrium enrichment level within 45 min after uridine addition. A shift of the temperature of infection from 37 to 31 C also led to a hyperenrichment of DI particles and pulse-labeling revealed a superimposed transient hyperenrichment. By contrast, cells continuously infected at 31 C showed a severe decrement in DI particles apparently because poliovirus DI particles behave as cold-sensitive mutants for RNA synthesis. Cycloheximide treatment early in the infection cycle also led to hyperenrichment. Study of the cycloheximide effect showed that the drug acted as if to change the input ratio of standard to DI particles. These effects on enrichment can be explained as aspects of two different phenomena: enrichment due to preferential DI RNA synthesis and enrichment due to preferential encapsidation of DI RNA. Both mechanisms probably play a role in the normal level of enrichment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357514"}
{"pmid": "4357513", "title": "Nucleic acid synthesis in cytoplasm of Yaba monkey tumor virus-infected cells.", "content": "Nucleic acid synthesis in cytoplasm of Yaba monkey tumor virus-infected cells. Yaba tumor virus progeny appeared in cynomolgus monkey kidney cells at 24 h postinfection and reached a plateau at 72 h in the first cycle of replication. Viral DNA synthesis was first detected at about 3 h and reached a peak in 18 h. Maximum coating of viral DNA in infected cells occurred at 4 days postinfection. Rapidly labeled RNA was synthesized in the cytoplasm of virus-infected cells. At 6 h postinfection 7 to 10S RNA was present; this species was present in greater amount at 12 h; at 24 h a truncated peak indicated the presence of 14 to 15S as well as 7 to 10S RNA. Hybridization data indicated that the largest peak of messenger RNA synthesis occurred at 11 to 13 h postinfection and a second, slightly smaller, peak occurred at 21 to 23 h.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357513"}
{"pmid": "4357515", "title": "Effect of dibutyryl cyclic AMP on the induction of Epstein-Barr virus in hybrid cells.", "content": "Effect of dibutyryl cyclic AMP on the induction of Epstein-Barr virus in hybrid cells. Treatment of Epstein-Barr virus (EBV) negative somatic cell hybrids with 5'-iododeoxyuridine (IUdR) induced synthesis of EBV antigens and virus particles. When dibutyryl cAMP (Bt(2)-cAMP) was present in medium after exposure of cultures to IUdR, the incidence of cells synthesizing EBV early and virus capsid antigens was increased. The time necessary for appearance of EBV particles after induction by IUdR was significantly reduced in the presence of Bt(2)-cAMP. This enhancement was evident to a lesser degree with 3':5' cAMP than with Bt(2)-cAMP and did not occur with any other of the related compounds tested. The response observed was dose dependent. Untreated (no IUdR) EBV negative hybrid cells exposed to Bt(2)-cAMP also synthesized EBV antigens. The concentration of intracellular cAMP may act as one of the control mechanisms selecting for gene expression in this system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357515"}
{"pmid": "4357516", "title": "Trypsin action on the growth of Sendai virus in tissue culture cells. 3. Structural difference of Sendai viruses grown in eggs and tissue culture cells.", "content": "Trypsin action on the growth of Sendai virus in tissue culture cells. 3. Structural difference of Sendai viruses grown in eggs and tissue culture cells. Polypeptides of egg-borne Sendai virus (egg Sendai), which is biologically active on the basis of criteria of the infectivity for L cells and of hemolytic and cell fusion activities, were compared by polyacrylamide gel electrophoresis with those of L cell-borne (L Sendai) and HeLa cell-borne Sendai (HeLa Sendai) viruses, which are judged biologically inactive by the above criteria. Densitometer profiles on the stained gels of egg Sendai resolved six polypeptides (virion protein [VP] 1 to VP6), in which VP2 and VP4 were identified as glycoproteins by PAS stain. Comparative electropherograms of both L Sendai and HeLa Sendai revealed that there were significantly larger amounts in the VP2 region of these viruses but VP4 was present only in greatly reduced amounts as compared to egg Sendai. It was also found that VP2 of L Sendai and HeLa Sendai consisted of two components, VP2a and VP2b, but the one of egg Sendai consisted of only VP2a. A mild trypsin treatment which converts both L Sendai and HeLa Sendai to a biologically active form selectively removed VP2b from these viruses and increased concomitantly the amounts of materials in the VP4 region. The same treatment of egg Sendai affected neither its biological activities nor its electropherogram. Consequently, gross polypeptide profiles on the stained gels of L Sendai and HeLa Sendai after trypsin treatment became favorably comparable to that of egg Sendai. Electrophoresis of labeled L Sendai and HeLa Sendai with a (3)H-amino acids mixture and (14)C-glucosamine resolved at least three glycoproteins, GP1, GP2, and GP3, each corresponding to VP2a, VP2b, and VP4, respectively. The trypsin treatment of these viruses removed almost all the radioactivity of GP2 and simultaneously increased the radioactive counts of GP3 and raised small amounts of rapidly moving heterogeneous glycoprotein, GP4. A possible relationship between the biological modification and the above characteristic polypeptide patterns of Sendai virus was discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357516"}
{"pmid": "4357517", "title": "RNA-DNA covalent bonds between the RNA primers and the DNA products formed by RNA tumor virus DNA polymerase.", "content": "RNA-DNA covalent bonds between the RNA primers and the DNA products formed by RNA tumor virus DNA polymerase. Initiation of DNA synthesis by endogenous RNA primer molecules was studied with three different RNA tumor viruses. The influence of the method of virus disruption on the observed RNA-DNA bonds was ascertained. Ether disrupted virions of both murine leukemia virus (MuLV) and the B77 strain of avian sarcoma virus (B77 virus) have rC-dC and rA-dA covalent linkages between RNA primers and newly synthesized DNA. None of the 14 other possible bonds were formed. Ether-disrupted virions of avian myeloblastosis virus (AMV) have rU-dC and rA-dA linkages. In contrast, work reported herein and from other laboratories shows that Nonidet P-40 (NP-40)-disrupted virions of all three viruses have only the rA-dA junction. Studies with virus particles which were first disrupted with ether and then treated with NP-40 indicated that the detergent treatment disallowed the formation of the ribopyrimidine-dC internucleotide bond. The same transfers are found with AMV in the presence or absence of actinomycin D, where only single-stranded DNA is formed. This finding is consistent with the notion that virtually all of the significant primers have been recognized. In contrast to mature virions, transfer experiments with ether-disrupted early harvest (5 min) MuLV showed only the rC-dC bond; the rA-dA bond was absent. The short-time harvest contains a significantly higher proportion of infectious virions than 24-h harvests. Also, since the RNA from early harvest virus is appreciably more homogenous than the RNA of mature MuLV, it is concluded that the ribopyrimidine-dC linkage is the more significant initiation event from a biochemical standpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357517"}
{"pmid": "4357518", "title": "DNA polymerase of murine sarcoma-leukemia virus: lack of detectable RNase H and low activity with viral RNA and natural DNA templates.", "content": "DNA polymerase of murine sarcoma-leukemia virus: lack of detectable RNase H and low activity with viral RNA and natural DNA templates. Kirsten murine sarcoma-leukemia virus (Ki-MSV[MLV]) was found to contain less RNase H per unit of viral DNA polymerase than avian Rous sarcoma virus (RSV). Upon purification by chromatography on Sephadex G-200 and subsequent glycerol gradient sedimentation the avian DNA polymerase was obtained in association with a constant amount of RNase H. By contrast, equally purified DNA polymerase of Ki-MSV(MLV) and Moloney [Mo-MSV(MLV)] lacked detectable RNase H if assayed with two homopolymer and phage fd DNA-RNA hybrids as substrates. On the basis of picomoles of nucleotides turned over, the ratio of RNase H to purified avian DNA polymerase was 1:20 and that of RNase H to purified murine DNA polymerase ranged between <1:2,800 and 5,000. Based on the same activity with poly (A).oligo(dT) the activity of the murine DNA polymerase was 6 to 60 times lower than that of the avian enzyme with denatured salmon DNA template or with avian or murine viral RNA templates assayed under various conditions (native, heat-dissociated, with or without oligo(dT) and oligo(dC) and at different template enzyme ratios). The template activities of Ki-MSV(MLV) RNA and RSV RNA were enhanced uniformly by oligo(dT) but oligo(dC) was much less efficient in enhancing the activity of MSV(MLV) RNA than that of RSV RNA. It was concluded that the purified DNA polymerase of Ki-MSV(MLV) differs from that of Rous sarcoma virus in its lack of detectable RNase H and in its low capacity to transcribe viral RNA and denatured salmon DNA. Some aspects of these results are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357518"}
{"pmid": "4357519", "title": "Effects of simian virus 40-induced transformation on isoaccepting species of transfer RNA from mouse fibroblasts.", "content": "Effects of simian virus 40-induced transformation on isoaccepting species of transfer RNA from mouse fibroblasts. Alterations in isoaccepting species of tRNA in mouse fibroblasts transformed by simian virus 40 were determined for alanine, arginine, histidine, leucine, lysine, phenylalanine, serine, tyrosine, and valine. Significant differences between transformed cells in culture and newborn mouse cells are attributed to tRNA alterations accompanying differentiation of mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357519"}
{"pmid": "4357520", "title": "Influence of complement on the neutralization of murine cytomegalovirus by rabbit antibody.", "content": "Influence of complement on the neutralization of murine cytomegalovirus by rabbit antibody. Antiserum against murine cytomegalovirus produced in the rabbit contained complement (C')-requiring neutralizing (CRN) antibody. The proportion of CRN was extremely high (up to 98%) during the early portion of an immunization procedure, whereas the antisera produced late had a much lower proportion that required C'. The antiserum produced was specific for MCMV with or without C'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357520"}
{"pmid": "4357522", "title": "Low-molecular-weight RNAs of murine sarcoma virus: comparative studies of free and 70S RNA-associated components.", "content": "Low-molecular-weight RNAs of murine sarcoma virus: comparative studies of free and 70S RNA-associated components. Several low-molecular-weight RNAs were released from mouse leukemia sarcoma virus 70S RNA under conditions of thermal denaturation. One of them, the 70S-associated 8S RNA, exhibits a number of structural properties characteristic of a previously described free viral 8S RNA. This similarity was revealed by polyacrylamide gel electrophoresis and nucleotide composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357522"}
{"pmid": "4357521", "title": "Formation of lipid-nucleotide complex by RNA tumor virus preparations.", "content": "Formation of lipid-nucleotide complex by RNA tumor virus preparations. RNA tumor virus preparations utilize alpha-(32)P-deoxyribonucleoside triphosphates as substrates to form lipid-nucleotide products which are tightly associated with protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357521"}
{"pmid": "4357523", "title": "Location of the T4 gene 32 protein binding site on simian virus 40 DNA.", "content": "Location of the T4 gene 32 protein binding site on simian virus 40 DNA. The T4 gene 32 protein, which binds to single-stranded but not duplex DNA, forms a specifically located denaturation loop in covalently closed circular simian virus 40 (SV40) DNA. Cleavage of the SV40 DNA-gene 32 protein complex with a restriction endonuclease from Hemophilus parainfluenzae shows the loop center to be at 0.46 on the SV40 DNA map. This is within one of the regions of SV40 DNA cleaved preferentially by the single-strand-specific nuclease S(1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357523"}
{"pmid": "4357526", "title": "Rapid screening assay for revertants derived from MSV-transformed cells.", "content": "Rapid screening assay for revertants derived from MSV-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357526"}
{"pmid": "4357529", "title": "The effect of prostaglandin E1 on norepinephrine-induced membrane depolarization and cyclic AMP accumulation in brown fat cells.", "content": "The effect of prostaglandin E1 on norepinephrine-induced membrane depolarization and cyclic AMP accumulation in brown fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357529"}
{"pmid": "4357530", "title": "Diurnal variation of plasma angiotensin II in man.", "content": "Diurnal variation of plasma angiotensin II in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357530"}
{"pmid": "4357531", "title": "Plasma lipid and lipoprotein levels in childhood and adolescence.", "content": "Plasma lipid and lipoprotein levels in childhood and adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357531"}
{"pmid": "4357533", "title": "Estrogen mercapturic acids in the adult male rat.", "content": "Estrogen mercapturic acids in the adult male rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357533"}
{"pmid": "4357534", "title": "Estrogen receptor-anti-estrogen complex: atypical binding by uterine nuclei and effects on uterine growth.", "content": "Estrogen receptor-anti-estrogen complex: atypical binding by uterine nuclei and effects on uterine growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357534"}
{"pmid": "4357535", "title": "The identification of androstenedione and androstenedione 3-enol glucuronide in the blood of a woman with an interstitial cell ovarian tumor after 4-14C-testosterone.", "content": "The identification of androstenedione and androstenedione 3-enol glucuronide in the blood of a woman with an interstitial cell ovarian tumor after 4-14C-testosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357535"}
{"pmid": "4357528", "title": "Structural and functional properties of synapses in insects.", "content": "Structural and functional properties of synapses in insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357528"}
{"pmid": "4357527", "title": "Subcellular localization of hexokinase in the rat cortex.", "content": "Subcellular localization of hexokinase in the rat cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357527"}
{"pmid": "4357542", "title": "Influence of deafferentation of the medial basal hypothalamus on the sensitivity of the brain to hyperbaric oxygen.", "content": "Influence of deafferentation of the medial basal hypothalamus on the sensitivity of the brain to hyperbaric oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357542"}
{"pmid": "4357543", "title": "Comparison of visual acuity tests and viewing condition interactions.", "content": "Comparison of visual acuity tests and viewing condition interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357543"}
{"pmid": "4357545", "title": "Adenoid cystic carcinoma of the male breast: report of a case.", "content": "Adenoid cystic carcinoma of the male breast: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357545"}
{"pmid": "4357546", "title": "Renin-secreting Wilms' tumor with severe hypertension. Report of a case and brief review of renin-secreting tumors.", "content": "Renin-secreting Wilms' tumor with severe hypertension. Report of a case and brief review of renin-secreting tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357546"}
{"pmid": "4357547", "title": "Metronidazole combined with diloxanide furoate in amoebic liver abscess.", "content": "Metronidazole combined with diloxanide furoate in amoebic liver abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357547"}
{"pmid": "4357549", "title": "Studies on polynucleotides containing hybrid sequences. Synthesis of oligonucleotides containing thymidine, adenosine, and a single deoxyribonucleotidyl-(3'-5')-ribonucleotide linkage.", "content": "Studies on polynucleotides containing hybrid sequences. Synthesis of oligonucleotides containing thymidine, adenosine, and a single deoxyribonucleotidyl-(3'-5')-ribonucleotide linkage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357549"}
{"pmid": "4357548", "title": "Enzymatic synthesis and crystallographic characterization of an isomorphous derivative of yeast formylatable methionine transfer ribonucleic acid containing iodocytidine.", "content": "Enzymatic synthesis and crystallographic characterization of an isomorphous derivative of yeast formylatable methionine transfer ribonucleic acid containing iodocytidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357548"}
{"pmid": "4357550", "title": "Inhibition of fumarylacetoacetate fumarylhydrolase by monovalent anions.", "content": "Inhibition of fumarylacetoacetate fumarylhydrolase by monovalent anions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357550"}
{"pmid": "4357551", "title": "Roles of zinc ion and reduced coenzyme in the formation of a transient chemical intermediate during the equine liver alcohol dehydrogenase catalyzed reduction of an aromatic aldehyde.", "content": "Roles of zinc ion and reduced coenzyme in the formation of a transient chemical intermediate during the equine liver alcohol dehydrogenase catalyzed reduction of an aromatic aldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357551"}
{"pmid": "4357552", "title": "Observations on the oxidation-reduction properties of bovine erythrocyte superoxide dismutase.", "content": "Observations on the oxidation-reduction properties of bovine erythrocyte superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357552"}
{"pmid": "4357553", "title": "Spin-labeled ribonuclease. A. Selective incorporation of a nitroxide spin label sensitive to active-center geometry.", "content": "Spin-labeled ribonuclease. A. Selective incorporation of a nitroxide spin label sensitive to active-center geometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357553"}
{"pmid": "4357554", "title": "Conformational studies of angiotensin peptides in aqueous solution by proton magnetic resonance.", "content": "Conformational studies of angiotensin peptides in aqueous solution by proton magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357554"}
{"pmid": "4357555", "title": "Model studies for molybdenum enzymes. Reduction of flavines by mu-oxo-bis(oxodihydroxo(L-cysteinato)molybdate(V)).", "content": "Model studies for molybdenum enzymes. Reduction of flavines by mu-oxo-bis(oxodihydroxo(L-cysteinato)molybdate(V)).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357555"}
{"pmid": "4357557", "title": "Oxidation-reduction potential dependence of low-temperature photoreactions of chloroplast photosystem. II.", "content": "Oxidation-reduction potential dependence of low-temperature photoreactions of chloroplast photosystem. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357557"}
{"pmid": "4357556", "title": "Polylysine-enhanced effectiveness of plastocyanin in photosystem. I.", "content": "Polylysine-enhanced effectiveness of plastocyanin in photosystem. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357556"}
{"pmid": "4357558", "title": "The oxidation mechanisms of thiosulphate and sulphide in Chlorobium thiosulphatophilum: roles of cytochrome c-551 and cytochrome c-553.", "content": "The oxidation mechanisms of thiosulphate and sulphide in Chlorobium thiosulphatophilum: roles of cytochrome c-551 and cytochrome c-553.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357558"}
{"pmid": "4357559", "title": "Effect of oxidizing treatment on chloroplast photosystem II reactions.", "content": "Effect of oxidizing treatment on chloroplast photosystem II reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357559"}
{"pmid": "4357560", "title": "Isolation of cytoplasmic glucocorticoid-binding protein(s) from rat liver by means of affinity chromatography, and its partial characterization.", "content": "Isolation of cytoplasmic glucocorticoid-binding protein(s) from rat liver by means of affinity chromatography, and its partial characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357560"}
{"pmid": "4357561", "title": "Progesterone-binding protein in human myometrium. Ligand specificity and some physicochemical characteristics.", "content": "Progesterone-binding protein in human myometrium. Ligand specificity and some physicochemical characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357561"}
{"pmid": "4357562", "title": "Binding of NAD+ to rabbit-muscle glyceraldehydephosphate dehydrogenase. The use of N-methylnicotinamidium chloride as a spectral and conformational probe.", "content": "Binding of NAD+ to rabbit-muscle glyceraldehydephosphate dehydrogenase. The use of N-methylnicotinamidium chloride as a spectral and conformational probe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357562"}
{"pmid": "4357563", "title": "The effects of trypsin on purified myelin.", "content": "The effects of trypsin on purified myelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357563"}
{"pmid": "4357564", "title": "Cell wall glycopeptides of Candida albicans serotypes A and B.", "content": "Cell wall glycopeptides of Candida albicans serotypes A and B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357564"}
{"pmid": "4357565", "title": "Structural and functional determinants of Mucor miehei protease. II. Circular dichroic studies on the native and periodate-oxidized enzyme.", "content": "Structural and functional determinants of Mucor miehei protease. II. Circular dichroic studies on the native and periodate-oxidized enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357565"}
{"pmid": "4357566", "title": "Mössbauer spectroscopy of iron in human and rabbit transferrin.", "content": "Mössbauer spectroscopy of iron in human and rabbit transferrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357566"}
{"pmid": "4357567", "title": "Simulated behavior states: an approach to specificity in psychobiological research.", "content": "Simulated behavior states: an approach to specificity in psychobiological research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357567"}
{"pmid": "4357568", "title": "Reactivity of vascular smooth muscle in hypertensive rats.", "content": "Reactivity of vascular smooth muscle in hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357568"}
{"pmid": "4357569", "title": "Myocardial nucleotide synthesis from purine bases and nucleosides. Comparison of the rates of formation of purine nucleotides from various precursors and identification of the enzymatic routes for nucleotide formation in the isolated rat heart.", "content": "Myocardial nucleotide synthesis from purine bases and nucleosides. Comparison of the rates of formation of purine nucleotides from various precursors and identification of the enzymatic routes for nucleotide formation in the isolated rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357569"}
{"pmid": "4357571", "title": "Incidence of autoantibodies in cancer patients.", "content": "Incidence of autoantibodies in cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357571"}
{"pmid": "4357570", "title": "Selective stimulation of renal nerves in the anesthetized dog. Effect on renin release during controlled changes in renal hemodynamics.", "content": "Selective stimulation of renal nerves in the anesthetized dog. Effect on renin release during controlled changes in renal hemodynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357570"}
{"pmid": "4357572", "title": "Prediction of the burden of released mental patients.", "content": "Prediction of the burden of released mental patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357572"}
{"pmid": "4357573", "title": "Social approaches to community mental health via intake or central reception services.", "content": "Social approaches to community mental health via intake or central reception services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357573"}
{"pmid": "4357574", "title": "Proceedings: Some aspects of freezing and drying of microorganisms on the basis of cellular water.", "content": "Proceedings: Some aspects of freezing and drying of microorganisms on the basis of cellular water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357574"}
{"pmid": "4357599", "title": "Chemical screening and evaluation of coronary and coronary-prone patients.", "content": "Chemical screening and evaluation of coronary and coronary-prone patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357599"}
{"pmid": "4357600", "title": "A new national strategy to make health services flexible and responsive.", "content": "A new national strategy to make health services flexible and responsive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357600"}
{"pmid": "4357601", "title": "Attempts to detect homologous autointerference in vivo with influenza virus and vesicular stomatitis virus.", "content": "Attempts to detect homologous autointerference in vivo with influenza virus and vesicular stomatitis virus. Von Magnus particles of influenza virus and defective interfering T particles of vesicular stomatitis virus were unable to provide significant protection of mice from disease or death when inoculated intranasally or intracerebrally along with moderate or high doses of homologous infectious challenge virus. However, yields of infectious virus from the affected organs were reduced as compared to controls inoculated with infectious virus alone. Serial intracerebral passage of vesicular stomatitis virus in mouse brain at high doses failed to produce T particles detectable by in vitro autointerference assays on BHK(21) cells, whether or not T particles were introduced along with B virions at the first passage. When very low challenge doses of infectious B virions were inoculated intracerebrally along with high doses of homologous defective particles, there was significant prolongation of life, although most mice died eventually of slowly progressing disease. Also, the virus yields in the brains of these mice were significantly reduced, and virus was no longer detectable in the brains of \"protected\" mice surviving for 10 days or more. Our results suggest that although homologous autointerference does occur in vivo, it is a more complex phenomenon than in vitro cell culture experiments might indicate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357601"}
{"pmid": "4357602", "title": "Differences in clinical and convalescent-phase antibodies of Rhesus monkeys infected with monkey pox, tanapox, and Yaba poxviruses.", "content": "Differences in clinical and convalescent-phase antibodies of Rhesus monkeys infected with monkey pox, tanapox, and Yaba poxviruses. Complement-fixing and complement-fixing inhibiting (CFI) antibodies were demonstrated in the clinical and convalescent stages, respectively, of rhesus monkeys infected with either monkey poxvirus, Tanapoxvirus, or Yaba poxvirus. Specificity of the CFI antibody was confirmed by its failure to cross-react with heterologous poxvirus antigens and by experiments demonstrating the CFI test as being antigen dependent. Serum containing CFI antibody neutralized homologous poxvirus but failed to agglutinate antigen-coated, tanned red blood cells. The application of CFI test as a seroepidemiologic tool for studies of poxvirus infection of man and simian monkeys and the biologic role of CFI antibody in pathogenesis were discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357602"}
{"pmid": "4357603", "title": "Immunity to chlamydial infections of the eye. V. Passive transfer of antitrachoma antibodies to owl monkeys.", "content": "Immunity to chlamydial infections of the eye. V. Passive transfer of antitrachoma antibodies to owl monkeys. Previous studies have shown that owl monkeys which have had a trachoma agent infection were subsequently highly resistant to challenge by both homologous and heterologous organisms. In the present study, passive transfer of owl monkey serum containing antitrachoma antibody from immune monkeys did not protect recipient monkeys from infectious challenge with homologous trachoma. Antibody was not detectable in eye secretions of the recipient monkeys until the intensity of infection was waning, suggesting but not proving that local antibody synthesis rather than simple transudation of serum antibody occurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357603"}
{"pmid": "4357604", "title": "Host responses to Epstein-Barr virus and cytomegalovirus infection in leprosy.", "content": "Host responses to Epstein-Barr virus and cytomegalovirus infection in leprosy. A study was undertaken in patients with leprosy to assess the contribution of cell-mediated immunity to the host response to Epstein-Barr virus (EBV) and cytomegalovirus (CMV) infection. Sixteen of 72 patients (22%) with lepromatous leprosy, with impaired cellular immunity, had anti-EBV titers of 1,640 or higher. Only 4 of 49 patients (8%) with tuberculoid leprosy, with intact cell-mediated immunity, attained the level of 1:640. The anti-EBV antibody titers were significantly higher in patients with lepromatous leprosy (P approximately 0.025). No significant differences were found in the level of anti-CMV antibody titers in patients with the two types of leprosy. The presence of high anti-EBV antibody titers in lepromatous leprosy suggests that cell-mediated immunity is a significant factor in host response to EBV infection. Host immune responses should be taken into consideration when assignment of an etiological role to EBV is based upon seroepidemiological data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357604"}
{"pmid": "4357605", "title": "Further studies on the carbohydrate metabolism of immature Schistosoma mansoni.", "content": "Further studies on the carbohydrate metabolism of immature Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357605"}
{"pmid": "4357606", "title": "An e.s.r. study of free-radical conversions in irradiated single crystals of N-acetylglycine in the temperature range 77-300 K.", "content": "An e.s.r. study of free-radical conversions in irradiated single crystals of N-acetylglycine in the temperature range 77-300 K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357606"}
{"pmid": "4357607", "title": "An enzyme histochemical study of mesothelial cells in rodents.", "content": "An enzyme histochemical study of mesothelial cells in rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357607"}
{"pmid": "4357608", "title": "Effects of acetazolamide on the urinary excretion of cyclic AMP and on the activity of renal adenyl cyclase.", "content": "Effects of acetazolamide on the urinary excretion of cyclic AMP and on the activity of renal adenyl cyclase. Acetazolamide, an inhibitor of the enzyme carbonic anhydrase, increased the urinary excretion of cyclic AMP in normal and parathyroidectomized rats. The increase was greater in rats with intact parathyroid glands than in parathyroidectomized rats. This rise in the urinary excretion of cyclic AMP was not due to an increase in urine flow or a change in urine pH. Furosemide caused an increase in urine flow, but did not affect the excretion of cyclic AMP or phosphate. Alkalinization of the urine with bicarbonate did not increase the urinary excretion of phosphate or cyclic AMP. Acetazolamide increased the productionof cyclic AMP by rat renal cortical slices in vitro. This effect was dose-dependent. Acetazolamide also stimulated the activity of renal cortical adenyl cyclase in a dose-dependent manner but had no effect on the activity of cyclic nucleotide phosphodiesterase. The pattern of urinary excretion of cyclic AMP and phosphate after administration of acetazolamide was similar to that observed in rats given parathyroid hormone. It is suggested that acetazolamide stimulates the renal production of cyclic AMP by activating adenyl cyclase and that this may be the mechanism by which this inhibitor of carbonic anhydrase produces phosphaturia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357608"}
{"pmid": "4357610", "title": "Plasma clearance rates and renal clearance of 3H-labeled cyclic AMP and 3H-labeled cyclic GMP in the dog.", "content": "Plasma clearance rates and renal clearance of 3H-labeled cyclic AMP and 3H-labeled cyclic GMP in the dog. Previously, in an attempt to understand the mechanisms involved in the regulation of plasma cyclic nucleotides, we measured concentrations of adenosine 3',5'-monophosphate (cAMP) and guanosine 3',5'-monophosphate (cGMP) in plasma from selected blood vessels of anesthetized dogs. The observation that the renal venous plasma concentrations of both cyclic nucleotides were less than arterial concentrations suggested that the kidney might be an important site for the elimination of these compounds from plasma and prompted further investigation of the renal handling of these compounds. Tracer doses of either [(3)H]cAMP or [(3)H]cGMP were administered to anesthetized dogs by constant intravenous infusion, and metabolic clearance rates were determined. Concentrations of endogenous cyclic nucleotide and of cyclic nucleotide radioactivity were measured in aortic and renal venous plasma as well as in urine. Renal venous plasma [(3)H]cGMP was 39% and [(3)H]cAMP was 65% of the concentration in arterial plasma. Endogenous cyclic nucleotide levels showed a similar relationship. The plasma clearance rates (PCR) were 271+/-27 ml/min (mean+/-SE) for cGMP and 261+/-17 for cAMP. The total kidney clearance (calculated as the renal plasma flow x renal cyclic nucleotide extraction ratio) accounted for 52+/-4% and 30+/-2% of the PCR for cGMP and cAMP, respectively. Only about two-thirds of the total kidney clearance of each cyclic nucleotide could be accounted for by urinary excretion, the remainder presumably being the result of renal metabolism. The urinary clearances of (3)H-labeled cGMP (40.9+/-4.2 ml/min) and endogenous cGMP (45.0+/-2.3 ml/min) were not significantly different from each other. Both were approximately 50% greater than the glomerular filtration rate, which was 27.1+/-2.0 ml/min, indicating that a significant amount of urinary cGMP is derived from plasma by tubular secretion. In contrast, the urinary clearances of (3)H-labeled cAMP (23.7+/-1.9 ml/min) and endogenous cAMP (27.2+/-2.6 ml/min) were nearly equal both to each other and to the glomerular filtration rate, which was 24.6+/-1.7 ml/min. Thus, in the dog, glomerular filtration of plasma cAMP appears to be responsible for most of the cAMP found in urine. Renla production of cAMP, which in humans contributes from a third to a half of the urinary cAMP, was quantitatively of minor importance in the dog.Thus, under the conditions of these experiments in dogs, renal elimination appears to be responsible for half of the PCR of cGMP and about a third of the PCR of cAMP. About a third of the renal elimination of both cyclic nucleotides appears to be due to metabolic degradation within the kidney, and the balance is due to excretion in the urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357610"}
{"pmid": "4357609", "title": "Hemolytic plaque formation by leukocytes in vitro. Control by vasoactive hormones.", "content": "Hemolytic plaque formation by leukocytes in vitro. Control by vasoactive hormones. Histamine, beta-adrenergic amines, and prostaglandins inhibited hemolytic plaque formation by splenic leukocytes from immunized mice. The same agents had previously been shown to prevent both the IgE-mediated release of histamine from human basophils and the immunologically specific cytolytic activity of murine lymphocytes, through stimulation of the production of cyclic AMP in leukocytes. We therefore tested the hypothesis that cyclic AMP might mediate an inhibitory effect of these drugs by comparing the ability of these agents to inhibit plaque formation with their effects on cyclic AMP accumulation in leukocytes. In splenic cells from three mouse strains, the dose-dependent effects of these agents of cyclic AMP correlated with their inhibition of plaque formation. Beta- but not alpha-adrenergic agonists were effective in both systems, and the effects of isoproterenol were inhibited by propranolol. Histamine was approximately equipotent with isoproterenol in both systems. Two prostaglandins (E(1) and E(2)) were effective in both systems, but prostaglandin F(2alpha) was not. Dibutyryl cyclic AMP, a lipid-soluble analog of the endogenous nucleotide, inhibited plaque formation by cells of all three strains. Theophylline, an inhibitor of cyclic AMP degradation, inhibited plaque formation slightly, but potentiated the effects of histamine, isoproterenol, and the prostaglandins on both cyclic AMP accumulation and plaque formation. Finally, cholera enterotoxin, a potent activator of adenyl cyclase, produced a delayed inhibition of plaque formation and a parallel increase in leukocyte cyclic AMP content; both effects of the toxin were blocked by canine antitoxin. These results suggest that leukocyte cyclic AMP may act as a \"second messenger\" to suppress plaque formation in vitro. The inhibitory effects of hormones and cyclic AMP on plaque formation are strikingly similar to their effects on in vitro models of immediate and cell-mediated hypersensitivity. The physiologic significance of these findings is not yet known.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357609"}
{"pmid": "4357612", "title": "Effect of glucagon on net splanchnic cyclic AMP production in normal and diabetic men.", "content": "Effect of glucagon on net splanchnic cyclic AMP production in normal and diabetic men. Glucagon activates hepatic adenylate cyclase, thereby increasing acutely the liver content of cyclic AMP (cAMP) as well as the release of cAMP into the hepatic vein. Insulin, on the other hand, antagonizes this glucagon-mediated cAMP production, thus providing a hypothetical mechanism through which insulin might correct some of the metabolic abnormalities of diabetes. To study this hormonal interaction in man, net splanchnic cAMP production (NScAMPP) was investigated in normal and insulin-dependent diabetic men under basal conditions and in response to intravenous glucagon, 50 ng/kg/min for 2 h. In normals (n=19), basal hepatic vein cAMP concentration was 23.6+/-1.1 nM and NScAMPP was 1.7+/-0.6 nmol/min. Glucagon stimulated NScAMPP in four normal subjects to a peak of 99.6+/-43 nmol/min at 25 min with a subsequent fall to 12.4+/-5.1 nmol/min by 90 min despite continuing glucagon infusion. Endogenous insulin secretion was stimulated as indicated by rising levels of immunoreactive insulin and C-peptide (connecting peptide) immunoreactivity, raising the possibility that endogenous insulin might be responsible for the fall in NScAMPP that followed the initial spike. In the diabetics (n=8), basal hepatic vein cAMP concentration was 24.7+/-1.2 nM and NScAMPP was undetectable. Glucagon stimulated NScAMPP in five diabetics to a peak of 169.9+/-42.6 with a subsequent fall to 17.4+/-3.9 nmol/min by 90 min even though endogenous insulin secretion was not stimulated (no rise in C-peptide immunoreactivity). Although the mean increase in NScAMPP was greater in the diabetics, the two groups did not differ significantly.Conclusions. In normal resting man the liver is a significant source of circulating cAMP. Diabetics do not release abnormally large amounts of hepatic cAMP under basal conditions. Glucagon markedly enhances hepatic cAMP release with a spike-decline pattern in both normal and diabetic men. The decline in hepatic cAMP release despite continuing glucagon stimulation is due to factors other than a stimulation of insulin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357612"}
{"pmid": "4357611", "title": "Sources of cyclic nucleotides in plasma.", "content": "Sources of cyclic nucleotides in plasma. In order to determine the sites of net production and removal of the cyclic nucleotides in plasma, various blood vessels were catheterized in 17 anesthetized dogs and arterial and venous concentrations of adenosine 3',5'-monophosphate (cAMP) and guanosine 3',5'-monophosphate (cGMP) were measured by radioimmunoassay. Aortic cAMP was 30+/-2 nM (mean+/-SE) and cGMP was 13+/-1 nM. There were no significant differences for either cyclic nucleotide between the concentration in the aorta and that in the inferior vena cava, coronary sinus, hepatic vein, and femoral vein. The concentration of cAMP in renal venous plasma was 25% lower than in aortic plasma, and renal venous cGMP was 51% lower than in the aorta. The pulmonary arterial concentrations of cAMP and cGMP were slightly lower than in the aorta. The concentration of cGMP in the superior mesenteric vein plasma was 83% greater than in aortic plasma; the concentration of cAMP in this vessel was only 16% greater than that in the aorta. Superior vena cava concentrations of both cyclic nucleotides were slightly greater than arterial concentrations. THE RESULTS SUGGEST THAT: (a) the kidneys are a major site of removal of both cyclic nucleotides from plasma. (b) The lungs may be a site of net addition of both cyclic nucleotides to plasma. (c) The small intestine is a site of net production of both cyclic nucleotides, particularly cGMP. (d) The liver probably removes cyclic nucleotides from plasma. (e) Since no other organs or regions studied added detectable net amounts of cyclic nucleotides to plasma, and since the turnover of these compounds in plasma is known to be rapid, the production of plasma cyclic nucleotides under basal conditions may well be the result of small net contributions may well be the result of small net contributions from many tissues or bidirectional fluxes between tissues and plasma, or both.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357611"}
{"pmid": "4357613", "title": "Induction of the platelet release reaction by phytohemagglutinin.", "content": "Induction of the platelet release reaction by phytohemagglutinin. We have previously shown that the erythroagglutinating phytohemagglutinin (E-PHA) from Phaseolus vulgaris binds to the surface of intact human platelets and that adenylate cyclase activity in the particulate fraction of E-PHA-treated platelets is lower than in comparable controls. We now find that E-PHA induces release of [(14)C]serotonin from platelets. Release follows binding of E-PHA, and a haptenic inhibitor of E-PHA binding prevents induction of release. E-PHA does not produce platelet lysis and has little effect on [(14)C]serotonin uptake. Platelets possess approximately 300,000 receptor sites of E-PHA per cell, and we estimate that about 15% of these sites must be occupied by E-PHA to initiate the release reaction. Prior incubation of platelets with prostaglandin E(1), theophylline, or dibutyryl cyclic AMP prevents E-PHA-induced release, although these agents have little effect on E-PHA binding to platelets. Thrombin and E-PHA produce different rates and extents of serotonin release. Thrombin (1 U/ml) causes release of 75-85% of platelet [(14)C]-serotonin, with half-maximal release occurring less than 0.5 min after thrombin addition. E-PHA, however, induces release of only 30-60% of platelet serotonin at a 10-fold slower rate. In addition, utilizing electron microscopy, we have observed striking differences in the morphological changes that occur in platelets exposed to E-PHA as compared with thrombin. Thus, the platelet release reaction may be triggered in part by binding of E-PHA to the cell surface, but this reaction only partially resembles that produced by thrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357613"}
{"pmid": "4357614", "title": "Separation of specific antibody-forming mouse cells by their adherence to insolubilized endogenous hormones.", "content": "Separation of specific antibody-forming mouse cells by their adherence to insolubilized endogenous hormones. Spleen cells from mice immunized with sheep red cells were separated by differential adherence to insolubilized histamine, catecholamines, and prostaglandins. The hormones were insolubilized by linking them to Sepharose beads through a protein carrier. We measured hemolytic plaque formation (per million splenic leukocytes) of cells which passed through columns of hormone-carrier-Sepharose beads (i.e., those cells that failed to bind). As compared with control (no column) cells, the number of plaque-forming cells was substantially reduced by passage through histamine, epinephrine, isoproterenol, and prostaglandin-E(2) columns. Plaque-forming cells were not significantly reduced by passage through carrier Sepharose (another control) or norepinephrine- and prostaglandin-F(2alpha)-carrier Sepharose columns. Thus, the ability of an insolubilized hormone preparation to subtract plaque-forming cells roughly correlated with the presence of pharmacologic receptors for the corresponding free hormones, as judged by stimulation of cyclic AMP accumulation in the same cells, reported previously. Both 19S and 7S plaque-forming cells were subtracted by columns prepared from pharmacologically active hormones, but none of the insolubilized hormones stimulated accumulation of intracellular cyclic AMP. The cell membrane phenomenon that allows adherence to a given hormone-carrier-bead column may be identical with the cell receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357614"}
{"pmid": "4357615", "title": "Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function.", "content": "Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function. Selective release of inflammatory materials from leukocyte lysosomes is reduced by compounds which increase cyclic 3',5'-adenosine monophosphate (cAMP) levels in suspensions of human leukocytes and is augmented by agents which increase cyclic 3',5'-guanosine monophosphate (cGMP) levels in these cell suspensions. Lysosomal enzymes are released in the absence of phagocytosis when cytochalasin B (5 mug/ml) converts polymorphonuclear leukocytes (PMN) to secretory cells: lysosomes merge directly with the plasma membrane upon encounter of PMN with zymosan, and cells selectively extrude substantial proportions of lysosomal, but not cytoplasmic enzymes. beta-Adrenergic stimulation of human leukocytes produced a dose-related reduction in beta-glucuronidase release (blocked by 10(-6) M propranolol) whereas alpha-adrenergic stimulation (phenylephrine plus propranolol) was ineffective. In contrast, the cholinergic agonist carbamylcholine chloride enhanced enzyme secretion, an effect blocked by 10(-6) M atropine. Incubation of cells with exogenous cAMP or with agents that increase endogenous cAMP levels (prostaglandin E1, histamine, isoproterenol, and cholera enterotoxin) reduced extrusion of lysosomal enzymes; in contrast, exogenous cGMP and carbamylcholine chloride (which increases endogenous cGMP levels), increased beta-glucuronidase release. Whereas colchicine (5 x 10(-4) M), a drug which impairs microtubule integrity, reduced selective enzyme release, deuterium oxide, which favors microtubule assembly, enhanced selective release of lyosomal enzymes. The data suggest that granule movement and acid hydrolase release from leukocyte lysosomes requires intact microtubules and may be modulated by adrenergic and cholinergic agents which appear to provoke changes in concentrations of cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357615"}
{"pmid": "4357616", "title": "The rapid changes of hepatic glycolytic enzymes and fructose-1,6-diphosphatase activities after intravenous glucagon in humans.", "content": "The rapid changes of hepatic glycolytic enzymes and fructose-1,6-diphosphatase activities after intravenous glucagon in humans. Glucagon (0.04-0.09 mg/kg/min) was given intravenously for either 2 or 3 min to eight patients with fasting-induced hypoglycemia. One child had hepatic phosphorylase deficiency, two children had glucose-6-phosphatase deficiency, two children had debrancher enzyme (amylo-1,6-glucosidase) deficiency, and two children and one adult had decreased hepatic fructose-1,6-diphosphatase (FDPase) activity. Liver biopsy specimens were obtained before and immediately after the glucagon infusion. The glucagon caused a significant increase in the activity of FDPase (from 50+/-10.0 to 72+/-11.7 nmol/mg protein/min) and a significant decrease in the activities of phosphofructokinase (PFK) (from 92+/-6.1 to 41+/-8.1 nmol/mg protein/min) and pyruvate kinase (PK) (from 309+/-39.4 to 165+/-23.9 nmol/mg protein/min). The glucagon infusion also caused a significant increase in hepatic cyclic AMP concentrations (from 41+/-2.6 to 233+/-35.6 pmol/mg protein). Two patients with debrancher enzyme deficiency who had biopsy specimens taken 5 min after the glucagon infusion had persistence of enzyme and cyclic AMP changes for at least 5 min. One child with glucose-6-phosphatase deficiency was given intravenous glucose (150 mg/kg/min) for a period of 5 min after the glucagon infusion and biopsy. The plasma insulin concentration increased from 8 to 152 muU/ml and blood glucose increased from 72 to 204 mg/100 ml. A third liver biopsy specimen was obtained immediately after the glucose infusion and showed that the glucagon-induced effects on PFK and FDPase were completely reversed. The glucagon infusion caused an increase in hepatic cyclic AMP concentration from 38 to 431 pmol/mg protein but the glucose infusion caused only a slight decrease in hepatic cyclic AMP concentration (from 431 to 384 pmol/mg protein), which did not appear to be sufficient to account for the changes in enzyme activities. Hepatic glucose-6-phosphatase and fructose-1,6-diphosphate aldolase activities were not altered by either the glucagon or the glucose infusion in any patients. Cyclic AMP (0.05 mmol/kg) was injected into the portal vein of adult rats and caused enzyme changes similar to those seen with glucagon administration in humans. Our findings suggest that rapid changes in the activities of PFK, PK, and FDPase are important in the regulation of hepatic glycolysis and gluconeogenesis, respectively, in humans and that cyclic AMP may mediate the glucagon- but probably not the glucose-insulin-induced changes in enzyme activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357616"}
{"pmid": "4357618", "title": "Cholinergic and beta-adrenergic compounds in the control of drinking behavior in the rat.", "content": "Cholinergic and beta-adrenergic compounds in the control of drinking behavior in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357618"}
{"pmid": "4357617", "title": "Effects of weight reduction on obesity. Studies of lipid and carbohydrate metabolism in normal and hyperlipoproteinemic subjects.", "content": "Effects of weight reduction on obesity. Studies of lipid and carbohydrate metabolism in normal and hyperlipoproteinemic subjects. Considerable controversy exists over the purported role of obesity in causing hyperglycemia, hyperlipemia, hyperinsulinemia, and insulin resistance; and the potential beneficial effects of weight reduction remain incompletely defined. Hypertriglyceridemia is one of the metabolic abnormalities proposed to accompany obesity, and in order to help explain the mechanisms leading to this abnormality we have proposed the following sequential hypothesis: insulin resistance --> hyperinsulinemia --> accelerated hepatic triglyceride(TG) production --> elevated plasma TG concentrations. To test this hypothesis and to gain insight into both the possible role of obesity in causing the above metabolic abnormalities and the potential benefit of weight reduction we studied the effects of weight loss on various aspects of carbohydrate and lipid metabolism in a group of 36 normal and hyperlipoproteinemic subjects. Only weak to absent correlations (r = 0.03 - 0.46) were noted between obesity and the metabolic variables measured. This points out that in our study group obesity cannot be the sole, or even the major, cause of these abnormalities in the first place. Further, we have observed marked decreases after weight reduction in fasting plasma TG (mean value: pre-weight reduction, 319 mg/100 ml; post-weight reduction, 180 mg/100 ml) and cholesterol (mean values: pre-weight reduction, 282 mg/100 ml; post-weight reduction, 223 mg/100 ml) levels, with a direct relationship between the magnitude of the fall in plasma lipid values and the height of the initial plasma TG level. We have also noted significant decreases after weight reduction in the insulin and glucose responses during the oral glucose tolerance test (37% decrease and 12% decrease, respectively). Insulin and glucose responses to liquid food before and after weight reduction were also measured and the overall post-weight reduction decrease in insulin response was 48% while the glucose response was relatively unchanged. In a subgroup of patients we studied both the degree of cellular insulin resistance and the rate of hepatic very low density (VLDL) TG production before and after weight reduction. These subjects demonstrated significant decreases after weight reduction in both degree of insulin resistance (33% decrease) and VLDL-TG production rates (40% decrease). Thus, weight reduction has lowered each of the antecedent variables (insulin resistance, hyperinsulinemia, and VLDL-TG production) that according to the above hypothesis lead to hypertriglyceridemia, and we believe the overall scheme is greatly strengthened. Furthermore, the consistent decreases in plasma TG and cholesterol levels seen in all subjects lead us to conclude that weight reduction is an important therapeutic modality for patients with endogenous hypertriglyceridemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357617"}
{"pmid": "4357619", "title": "Calciferol metabolism and intestinal calcium transport in the chick with reduced renal function.", "content": "Calciferol metabolism and intestinal calcium transport in the chick with reduced renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357619"}
{"pmid": "4357620", "title": "Connective tissue activation. VI. The effects of cylic nucleotides on human synovial cells in vitro.", "content": "Connective tissue activation. VI. The effects of cylic nucleotides on human synovial cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357620"}
{"pmid": "4357621", "title": "Effect of estrogens and a progestogen on platelet adhesiveness and aggregation in rabbits.", "content": "Effect of estrogens and a progestogen on platelet adhesiveness and aggregation in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357621"}
{"pmid": "4357622", "title": "Phosphorylative capacity of liver mitochondria with an elevated ratio of cytochrome c+c1 to cytochrome a(+a3).", "content": "Phosphorylative capacity of liver mitochondria with an elevated ratio of cytochrome c+c1 to cytochrome a(+a3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357622"}
{"pmid": "4357623", "title": "Sarcoplasmic reticulum in the portal vein heart and ventricle of the cyclostome Myxine glutinosa (L.).", "content": "Sarcoplasmic reticulum in the portal vein heart and ventricle of the cyclostome Myxine glutinosa (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357623"}
{"pmid": "4357624", "title": "Phosphorylation of cardiac native tropomyosin and troponin: inhibitory effect of actomyosin and possible presence of endogenous myofibrillar-located cyclic-AMP-dependent protein kinase.", "content": "Phosphorylation of cardiac native tropomyosin and troponin: inhibitory effect of actomyosin and possible presence of endogenous myofibrillar-located cyclic-AMP-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357624"}
{"pmid": "4357625", "title": "Parotid tumors and the orbital apex syndrome.", "content": "Parotid tumors and the orbital apex syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357625"}
{"pmid": "4357626", "title": "Enhanced detection of a skeletal lesion with delayed 99mTc-polyphosphate bone scanning.", "content": "Enhanced detection of a skeletal lesion with delayed 99mTc-polyphosphate bone scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357626"}
{"pmid": "4357627", "title": "Effect of various steroids and ACTH on distribution of zoxazolamine in rats.", "content": "Effect of various steroids and ACTH on distribution of zoxazolamine in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357627"}
{"pmid": "4357633", "title": "Lipid infusions in man. Ultrastructural studies on blood platelet uptake of fat particles.", "content": "Lipid infusions in man. Ultrastructural studies on blood platelet uptake of fat particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357633"}
{"pmid": "4357632", "title": "In vitro effects of lipids on fibrinolysis.", "content": "In vitro effects of lipids on fibrinolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357632"}
{"pmid": "4357629", "title": "mRNA transcription linked to the morphological and plasma membrane changes induced by cyclic AMP in tumour cells.", "content": "mRNA transcription linked to the morphological and plasma membrane changes induced by cyclic AMP in tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357629"}
{"pmid": "4357639", "title": "The effect of clonazepam (Ro 5-4023) in the syndrome of infantile spasms with hypsarrhythmia and in petit mal variant of Lennox syndrome. Preliminary report.", "content": "The effect of clonazepam (Ro 5-4023) in the syndrome of infantile spasms with hypsarrhythmia and in petit mal variant of Lennox syndrome. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357639"}
{"pmid": "4357630", "title": "Optical recording of impulses in individual neurones of an invertebrate central nervous system.", "content": "Optical recording of impulses in individual neurones of an invertebrate central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357630"}
{"pmid": "4357643", "title": "Adenyl cyclase.", "content": "Adenyl cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357643"}
{"pmid": "4357644", "title": "The chemistry and biological properties of nucleotides related to nucleoside 3',5'-cyclic phosphates.", "content": "The chemistry and biological properties of nucleotides related to nucleoside 3',5'-cyclic phosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357644"}
{"pmid": "4357645", "title": "Clinical studies and applications of cyclic nucleotides.", "content": "Clinical studies and applications of cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357645"}
{"pmid": "4357647", "title": "Analysis of the photochemical isomers of ergosterol by column chromatography.", "content": "Analysis of the photochemical isomers of ergosterol by column chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357647"}
{"pmid": "4357646", "title": "Protein kinases and protein kinase substrates.", "content": "Protein kinases and protein kinase substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357646"}
{"pmid": "4357648", "title": "Determination of nicotinamide in some injections of B-complex vitamins by thin-layer chromatography.", "content": "Determination of nicotinamide in some injections of B-complex vitamins by thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357648"}
{"pmid": "4357649", "title": "Male infertility caused by abnormal androgen production in the adrenal cortex.", "content": "Male infertility caused by abnormal androgen production in the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357649"}
{"pmid": "4357650", "title": "Growth of Clostridium perfringens in food proteins previously exposed to proteolytic bacilli.", "content": "Growth of Clostridium perfringens in food proteins previously exposed to proteolytic bacilli. Proteolytic sporeforming bacteria capable of surviving processing heat treatments in synthetic or fabricated protein foods exhibited no antagonistic effects on growth of Clostridium perfringens, but instead shortened the lag of subsequent growth of C. perfringens in sodium caseinate and isolated soy protein. Bacillus subtilis A cells were cultured in 3% sodium caseinate or isolated soy protein solutions. The subsequent effect on the lag time and growth of C. perfringens type A (strain S40) at 45 C was measured by colony count or absorbance at 650 nm, or both. B. subtilis incubation for 12 h or more in sodium caseinate reduced the C. perfringens lag by 3 h. Incubation of 8 h or more in isolated soy protein reduced the lag time by 1.5 h. Molecular sieving of the B. subtilis-treated sodium caseinate revealed that all molecular sizes yielded a similar reduced lag time. Diethylaminoethyl-Sephadex ion exchange fractionation and subsequent amino acid analysis indicated that the lag time reduction caused by B. subtilis incubation was not related to charge of the peptides nor to their amino acid composition. Apparently the shortened C. perfringens lag in these B. subtilis-hydrolyzed food proteins was a result of the protein being more readily available for utilization by C. perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357650"}
{"pmid": "4357651", "title": "Identification of the toxic principle in a sample of poaefusarin.", "content": "Identification of the toxic principle in a sample of poaefusarin. A sample of poaefusarin (a mycotoxin suspected of being one of the toxins involved in alimentary toxic aleukia in the U.S.S.R.) was received from a Soviet scientist for evaluation and comparison with other mycotoxins. Although poaefusarin is presumed to be a steroid, analyses by thin-layer chromatography, gas-liquid chromatography, and infrared, ultraviolet, and mass spectrometry could not confirm the presence of a steroid structure. However, 2.5% of the sample was made up of the trichothecene T-2 toxin, an amount sufficient to explain the toxicity found in the rat and rabbit skin toxicity tests. In addition, neosolaniol (0.14%), T-2 tetraol (0.6%), and zearalenone (F-2) (0.43%) were present in the sample. Since the toxicity was found to be associated only with T-2 toxin, no attempt was made to determine the nature of the other nontoxic components of the sample.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357651"}
{"pmid": "4357652", "title": "Inactivation of foot-and-mouth disease virus with ethylenimine.", "content": "Inactivation of foot-and-mouth disease virus with ethylenimine. Foot-and-mouth disease virus (FMDV) was inactivated by ethylenimine (EI) at three concentrations and two temperatures. Comparison of inactivation kinetics and the antigenic and immunogenic potency of EI and N-acetylethylenimine (AEI)-inactivated FMDV indicates that EI has nearly optimal characteristics as an inactivant for FMDV vaccine preparation. Although AEI-inactivated FMDV has proved to be a potent specific immunogen, an equivalent percentage of EI inactivated FMDV at substantially faster rates and produced an equally potent immunogen. In addition, EI inactivated FMDV at rates that were essentially linear throughout the loss of nearly all measurable infectivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357652"}
{"pmid": "4357653", "title": "Simplified method for purification of Clostridium perfringens type A enterotoxin.", "content": "Simplified method for purification of Clostridium perfringens type A enterotoxin. Purification of Clostridium perfringens type A enterotoxin from sporulated cells was simplified. The method consisted of precipitation of the enterotoxin from the extract of sonically treated cells at 40% saturation of ammonium sulfate at pH 7, differential solubilization in 0.02 M phosphate buffer, pH 6.7, and repeated gel filtration on Sephadex G-200. The purified enterotoxin was at least 98% pure in ultracentrifugation, polyacrylamide gel electrophoresis, and agar gel double diffusion. Recovery was over 74% from the sporulated cell extract. The toxin had biological activities of at least 4,700 mouse intravenous minimal lethal doses/mg of N, 3,900 capillary permeability-increasing U/mg of N in the guinea pig skin, and 210 rabbit intestinal loop distension U/mg of N. The toxin, containing no hexose, lipid, or nucleic acid, appeared to be identical in sedimentation constant, isoelectric point, and ultraviolet absorption spectrum to the toxin purified previously by different procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357653"}
{"pmid": "4357654", "title": "Proton magnetic double-resonance study of angiotensin II (Asn1Val5) in aqueous solution employing correlation spectroscopy. Assignment of peptide NH resonances and transfer of saturation from water.", "content": "Proton magnetic double-resonance study of angiotensin II (Asn1Val5) in aqueous solution employing correlation spectroscopy. Assignment of peptide NH resonances and transfer of saturation from water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357654"}
{"pmid": "4357655", "title": "Kinetic studies of fluoride binding by cytochrome c peroxidase.", "content": "Kinetic studies of fluoride binding by cytochrome c peroxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357655"}
{"pmid": "4357656", "title": "Kinetic and equilibrium studies of cyanide binding by cytochrome c peroxidase.", "content": "Kinetic and equilibrium studies of cyanide binding by cytochrome c peroxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357656"}
{"pmid": "4357658", "title": "Functional groups of diphosphopyridine nucleotide linked isocitrate dehydrogenase from bovine heart. II. Studies of an active amino group by reaction with aldehydes.", "content": "Functional groups of diphosphopyridine nucleotide linked isocitrate dehydrogenase from bovine heart. II. Studies of an active amino group by reaction with aldehydes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357658"}
{"pmid": "4357657", "title": "Functional groups of diphosphopyridine nucleotide linked isocitrate dehydrogenase from bovine heart. I. Studies of an active amino group by amidination, arylation, acetylation, and carbamylation.", "content": "Functional groups of diphosphopyridine nucleotide linked isocitrate dehydrogenase from bovine heart. I. Studies of an active amino group by amidination, arylation, acetylation, and carbamylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357657"}
{"pmid": "4357660", "title": "An unproductive binary complex of liver alcohol dehydrogenase and a chromophoric aldehyde.", "content": "An unproductive binary complex of liver alcohol dehydrogenase and a chromophoric aldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357660"}
{"pmid": "4357659", "title": "Electronic substituent effects during the liver alcohol dehydrogenase catalyzed reduction of aromatic aldehydes.", "content": "Electronic substituent effects during the liver alcohol dehydrogenase catalyzed reduction of aromatic aldehydes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357659"}
{"pmid": "4357662", "title": "Regulation of pea leaf ribulose-5-phosphate kinase activity.", "content": "Regulation of pea leaf ribulose-5-phosphate kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357662"}
{"pmid": "4357661", "title": "Modulation of succinate dehydrogenase in response to environmental stress conditions of hypobaria and hypoxia.", "content": "Modulation of succinate dehydrogenase in response to environmental stress conditions of hypobaria and hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357661"}
{"pmid": "4357663", "title": "Phosphorylation of muscle proteins by cyclic adenosine 3',5'-monophosphate-dependent protein kinase from muscle.", "content": "Phosphorylation of muscle proteins by cyclic adenosine 3',5'-monophosphate-dependent protein kinase from muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357663"}
{"pmid": "4357664", "title": "Adenylate kinase from Thiobacillus neapolitanus. Unique properties, possibly designed to serve a unique metabolic function.", "content": "Adenylate kinase from Thiobacillus neapolitanus. Unique properties, possibly designed to serve a unique metabolic function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357664"}
{"pmid": "4357665", "title": "A surface p-nitrophenyl phosphatase of frog gastric mucosa.", "content": "A surface p-nitrophenyl phosphatase of frog gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357665"}
{"pmid": "4357666", "title": "Further characterization of a specific p-nitrophenylphosphatase from baker's yeast.", "content": "Further characterization of a specific p-nitrophenylphosphatase from baker's yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357666"}
{"pmid": "4357667", "title": "Purification of phospholipase C (alpha-toxin) from Clostridium perfringens.", "content": "Purification of phospholipase C (alpha-toxin) from Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357667"}
{"pmid": "4357668", "title": "Distribution of lysosomal enzymes between parenchymal and Kupffer cells of rat liver.", "content": "Distribution of lysosomal enzymes between parenchymal and Kupffer cells of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357668"}
{"pmid": "4357669", "title": "The integrity of human lymphoblastoid RNA after incorporation by human skin fibroblasts.", "content": "The integrity of human lymphoblastoid RNA after incorporation by human skin fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357669"}
{"pmid": "4357671", "title": "Hydroxylamine-O-sulfonic acid: in vitro and possible in vivo reaction with DNA.", "content": "Hydroxylamine-O-sulfonic acid: in vitro and possible in vivo reaction with DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357671"}
{"pmid": "4357673", "title": "Platelet function studies in coronary artery disease.", "content": "Platelet function studies in coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357673"}
{"pmid": "4357672", "title": "Changes in microsomal enzyme activities during DAB carcinogenesis.", "content": "Changes in microsomal enzyme activities during DAB carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357672"}
{"pmid": "4357674", "title": "Hyper-low density lipoproteinemia in United States Air Force recruits.", "content": "Hyper-low density lipoproteinemia in United States Air Force recruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357674"}
{"pmid": "4357677", "title": "A study on the role of pituitary ACTH in the aldosterone production of sodium depleted rats.", "content": "A study on the role of pituitary ACTH in the aldosterone production of sodium depleted rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357677"}
{"pmid": "4357679", "title": "Adrenocortical responsiveness after long-term corticosteroid therapy in childhood nephrosis.", "content": "Adrenocortical responsiveness after long-term corticosteroid therapy in childhood nephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357679"}
{"pmid": "4357678", "title": "Familial congenital adrenal hypoplasia.", "content": "Familial congenital adrenal hypoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357678"}
{"pmid": "4357680", "title": "Alteration of binding specificity of murine myeloma protein-315 to 2,4-dinitrophenyl and 2,4,6-trinitrophenyl ligands.", "content": "Alteration of binding specificity of murine myeloma protein-315 to 2,4-dinitrophenyl and 2,4,6-trinitrophenyl ligands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357680"}
{"pmid": "4357681", "title": "Letter: A phosphodiesterase from Enterobacter aerogenes.", "content": "Letter: A phosphodiesterase from Enterobacter aerogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357681"}
{"pmid": "4357682", "title": "Surface markers on human B and T lymphocytes. II. Presence of Epstein-Barr virus receptors on B lymphocytes.", "content": "Surface markers on human B and T lymphocytes. II. Presence of Epstein-Barr virus receptors on B lymphocytes. Human peripheral lymphocytes were investigated for receptors binding Epstein-Barr virus (EBV) because of the regular association of this virus with infectious mononucleosis and Burkitt's lymphoma. This was done by a cytoadherence technique where virus-producing cells, displaying fresh viral determinants in their cytoplasmatic membrane, were mixed with lymphocytes. Unfractionated lymphocytes were found to adhere to these cells in contrast to column-purified T lymphocytes. The specificity of the binding was confirmed by blocking experiments that showed that sera containing high titers of antibodies directed against the virus could partially inhibit the adherence in contrast to low-titer sera. It is concluded that B lymphocytes, in contrast to T lymphocytes, have receptors for EBV. In a second line of experiments it was found that established human lymphoblastoid lines that carry the EBV genome had receptors characteristic for B lymphocytes and did not form T-lymphocyte rosettes. In contrast, a line of known T-lymphocyte origin that did not carry the EBV genome had receptors characteristic for T lymphocytes. EBV-transformed simian lymphoblastoid lines had surface markers indicating a B-lymphocyte origin in contrast to HVS-transformed simian lines that lacked surface immunoglobulin but carried receptors for sheep red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357682"}
{"pmid": "4357683", "title": "Comparison of the yield of infectious virus from clones of human and simian lymphoblastoid lines transformed by Epstein-Barr virus.", "content": "Comparison of the yield of infectious virus from clones of human and simian lymphoblastoid lines transformed by Epstein-Barr virus. Three lymphoblastoid cell lines, of human, squirrel monkey, and marmoset origin, all transformed by the same strain of Epstein-Barr virus (EBV), differed markedly in their content of infectious virus. Single cell clones were obtained from each line to learn whether these differences were dependent upon factors shared by all cells in each line or upon factors present only in a proportion of the total cell population. A total of 17 primary clones were examined: 6 human, 6 squirrel monkey, and 5 marmoset. Cloning efficiency on human placental cell feeder layers varied from 16 to 24%. EBV antiserum, present in the cloning suspension, was shown to neutralize all extracellular virus. 15 of the 17 clones released EBV as measured by the transformation assay. Titers of infectious virus released by daughter clones paralleled titers of virus in the parent line. The median virus titers from human, squirrel monkey, and marmoset clones were respectively 10(1.5), 10(3.0), and 10(4.3) 50% transforming doses per 0.2 ml. The median yield of virus from clones of the three species was, respectively, 4, 96, and 786 transforming units per 1,000 cells containing viral capsid antigen. Two nonproducer clones (one human and one squirrel monkey) did not release infectious virus after treatment with 5'-bromodeoxyuridine, or with X ray followed by co-cultivation with marmoset leukocytes. The nonproducer clones could not be superinfected by biologically active EBV. These results show that differences in production of infectious EBV among the lines tested are reflected in the majority of cells of these lines. The data imply that the mechanism for regulation of the expression of the EBV genome is cellular rather than viral in origin. There are presumably genetic differences among primate species in this regulatory process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357683"}
{"pmid": "4357684", "title": "Adaptations of energy metabolism in the cultivated macrophage.", "content": "Adaptations of energy metabolism in the cultivated macrophage. Adaptive changes in energy metabolism, as reflected by pyruvate kinase and cytochrome oxidase activities, were examined during in vitro differentiation of the cultivated macrophage. Serum concentrations of tissue culture media, which directly influence endocytic activity, and ambient oxygen tension were both shown to influence pyruvate kinase and cytochrome oxidase activities. Cells maintained in high serum concentrations (30% newborn calf serum [NBCS]) exhibited a 300-400% increase in pyruvate kinase activity and a 40% increase in cytochrome oxidase activity, whereas cells maintained in low serum concentrations (2% NBCS) exhibited a lesser increase (65%) in pyruvate kinase activity and no change in cytochrome oxidase activity. Anaerobiosis resulted in additional alterations in pyruvate kinase and cytochrome oxidase activities. Cells maintained for 48-72 h under anaerobic conditions exhibited a 500-600% increase in pyruvate kinase activity and a 40% decrease in cytochrome oxidase activity. Increased pyruvate kinase activity was dependent on continued protein synthesis. Enzyme increases occurred in anaerobically cultured cells despite an overall reduction in cell protein synthesis. It is suggested that adaptive changes in pyruvate kinase and cytochrome oxidase activity resulting from alterations in either serum concentration or ambient oxygen tension are regulated by two independent mechanisms. One mechanism is aimed at providing energy for endocytic activity and the other in compensating for impaired oxidative metabolism during anaerobiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357684"}
{"pmid": "4357670", "title": "Study of methyl-CCNU(NSC-95441) in the treatment of lung cancer.", "content": "Study of methyl-CCNU(NSC-95441) in the treatment of lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357670"}
{"pmid": "4357685", "title": "A suppression of cellular immunity in patients with multiple sclerosis.", "content": "A suppression of cellular immunity in patients with multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357685"}
{"pmid": "4357686", "title": "Preparation and characterization of an immuno-electron microscope tracer consisting of a heme-octapeptide coupled to fab.", "content": "Preparation and characterization of an immuno-electron microscope tracer consisting of a heme-octapeptide coupled to fab. A heme-octapeptide (mol wt 1,550) has been obtained from cytochrome c by successive pepsin and trypsin hydrolysis and purified by gel filtration and countercurrent distribution. It possesses peroxidatic activity characterized by an apparent K(m) of 0.2 M, an apparent v(max) of 4 mmol/min per mg of peptide, and a pH optimum of 7.0. Using a novel two-step conjugation procedure, the heme-octapeptide was coupled to rabbit Fab antibody fragments by first derivatizing it with the N-hydroxysuccinimide ester of p-formylbenzoic acid and subsequently allowing it to form a Schiff base with the amino groups of Fab. Stable covalent linkages were then obtained by reduction of the Schiff bases with sodium borohydride. The conjugate consists of approximately 2 heme-octapeptides attached to each Fab molecule. The molecular weight is 45,000 daltons when coupled to sheep Fab and 50,000 daltons with a Stokes radius of 32 A, when conjugated to rabbit Fab. Its peroxidatic activity is characterized by an apparent K(m) of 0.4 M, an apparent v(max) of 0.4 mmol/min and per mg of attached heme-octapeptide and a pH optimum of 7.0. The conjugate has been used for the localization at the electron microscope level of secretory immunoglobulins in the mammary gland of lactating rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357686"}
{"pmid": "4357687", "title": "Renin content in subcellular fractions of normal rat kidney extract.", "content": "Renin content in subcellular fractions of normal rat kidney extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357687"}
{"pmid": "4357689", "title": "Role of cyclic AMP in the action of antidiuretic hormone on kidney.", "content": "Role of cyclic AMP in the action of antidiuretic hormone on kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357689"}
{"pmid": "4357690", "title": "Uptake of estradiol by the rat pineal organ. Effects of cervical sympathectomy, stage of the estrous cycle and estradiol treatment.", "content": "Uptake of estradiol by the rat pineal organ. Effects of cervical sympathectomy, stage of the estrous cycle and estradiol treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357690"}
{"pmid": "4357691", "title": "Synthesis and toxicity evaluation of aflatoxin P.", "content": "Synthesis and toxicity evaluation of aflatoxin P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357691"}
{"pmid": "4357692", "title": "New applications of electron spin resonance to problems in biochemistry and pharmacology.", "content": "New applications of electron spin resonance to problems in biochemistry and pharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357692"}
{"pmid": "4357695", "title": "Enigma and dilemma of the pulmonary nodule.", "content": "Enigma and dilemma of the pulmonary nodule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357695"}
{"pmid": "4357694", "title": "Aldosterone: review of its physiology and diagnostic aspects of primary aldosteronism.", "content": "Aldosterone: review of its physiology and diagnostic aspects of primary aldosteronism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357694"}
{"pmid": "4357696", "title": "Dissociation between human platelet agglomerating activity and factor VIII procoagulant activity of bovine plasma preparations by chemical treatment. II. Effect of periodate oxidation.", "content": "Dissociation between human platelet agglomerating activity and factor VIII procoagulant activity of bovine plasma preparations by chemical treatment. II. Effect of periodate oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357696"}
{"pmid": "4357693", "title": "The influence of p,p'-DDT, alpha-chlordane, heptachlor and endrin on hepatic and renal carbohydrate metabolism and cyclic AMP-adenyl cyclase system.", "content": "The influence of p,p'-DDT, alpha-chlordane, heptachlor and endrin on hepatic and renal carbohydrate metabolism and cyclic AMP-adenyl cyclase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357693"}
{"pmid": "4357705", "title": "Feline viral rhinotracheitis (FVR).", "content": "Feline viral rhinotracheitis (FVR).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357705"}
{"pmid": "4357704", "title": "Feline viral infections.", "content": "Feline viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357704"}
{"pmid": "4357706", "title": "Ultrastructural and histochemical demonstration of myoepithelium in mixed tumors of the canine mammary gland.", "content": "Ultrastructural and histochemical demonstration of myoepithelium in mixed tumors of the canine mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357706"}
{"pmid": "4357707", "title": "Immunologic response of the bovine fetus to inactivated infectious bovine rhinotracheitis-infectious pustular vulvovaginitis virus.", "content": "Immunologic response of the bovine fetus to inactivated infectious bovine rhinotracheitis-infectious pustular vulvovaginitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357707"}
{"pmid": "4357709", "title": "Lithium carbonate and sleep in affective disorders. Further considerations.", "content": "Lithium carbonate and sleep in affective disorders. Further considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357709"}
{"pmid": "4357708", "title": "Role of horse fly (Tabanus fuscicostatus Hine) and stable fly (Stomoxys calcitrans L.) in transmission of equine infectious anemia to ponies in Louisiana.", "content": "Role of horse fly (Tabanus fuscicostatus Hine) and stable fly (Stomoxys calcitrans L.) in transmission of equine infectious anemia to ponies in Louisiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357708"}
{"pmid": "4357710", "title": "Respiration-driven proton translocation by yeast mitochondria with differing efficiencies of oxidative phosphorylation.", "content": "Respiration-driven proton translocation by yeast mitochondria with differing efficiencies of oxidative phosphorylation. Measurements were made of the stoicheiometry of proton translocation coupled to respiration in mitochondria from Candida utilis where the number of functional energy-conservation sites between intramitochondrial NADH and oxygen was one in a mutant with a novel oxidase (Downie & Garland, 1972), two in sulphate-deficient cells (Haddock & Garland, 1971) or three in glycerol-limited cells (Light & Garland, 1971). The stoicheiometries of protons translocated per atom of oxygen utilized (i.e. -->H(+)/2e(-) ratio; Mitchell, 1966) were close to 2.0, 4.0 and 6.0 respectively. Thus by using the same substrate (intramitochondrial NADH) and oxygen throughout, the -->H(+)/2e(-) ratio is shown to be 2.0 per energy-conservation site when the number of such sites is varied from one to three.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357710"}
{"pmid": "4357711", "title": "An antimycin A- and cyanide-resistant variant of Candida utilis arising during copper-limited growth.", "content": "An antimycin A- and cyanide-resistant variant of Candida utilis arising during copper-limited growth. 1. During copper-limited growth of Candida utilis in continuous culture on a non-fermentable carbon and energy source there is a selective pressure favouring the emergence of variants that are less dependent on copper. 2. We describe the properties of such a variant that by-passes cytochrome oxidase (EC 1.9.3.1) by utilizing an alternative oxidase communicating with the respiratory chain at about the level of cytochrome b. 3. Both direct studies of isolated mitochondria and calculations based on growth parameters showed that only one of the normal three phosphorylation sites was active. This site was localized between NADH and the cytochromes. 4. Growth of the variant with copper-supplemented media resulted in the return of cytochrome oxidase but not the loss of the alternative oxidase. 5. The alternative oxidase is inhibited by substituted benzhydroxamic acids. 6. Submitochondrial particles from the variant did not exhibit any novel electron-paramagnetic-resonance-spectroscopy features at about g=2.0 either at 80 degrees K or 12 degrees K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357711"}
{"pmid": "4357714", "title": "Biochemical effects of the porphyrinogenic drug allylisopropylacetamide. A comparative study with phenobarbital.", "content": "Biochemical effects of the porphyrinogenic drug allylisopropylacetamide. A comparative study with phenobarbital. Successive administrations of allylisopropylacetamide, a potent porphyrinogenic drug, increase liver weight, microsomal protein and phospholipid contents. There is an increase in the rate of microsomal protein synthesis in vivo and in vitro. The drug decreases microsomal ribonuclease activity and increases NADPH-cytochrome c reductase activity. Phenobarbital, which has been reported to exhibit all these changes mentioned, is a weaker inducer of delta-aminolaevulinate synthetase and increases the rate of haem synthesis only after a considerable time-lag in fed female rats, when compared with the effects observed with allylisopropylacetamide. Again, phenobarbital does not share the property of allylisopropylacetamide in causing an initial decrease in cytochrome P-450 content. Haematin does not counteract most of the biochemical effects caused by allylisopropylacetamide, although it is quite effective in the case of phenobarbital. Haematin does not inhibit the uptake of [2-(14)C]allylisopropylacetamide by any of the liver subcellular fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357714"}
{"pmid": "4357715", "title": "Glucose metabolism in the newborn rat. Hormonal effects in vivo.", "content": "Glucose metabolism in the newborn rat. Hormonal effects in vivo. 1. The concentrations of liver glycogen and plasma d-glucose were measured in caesarian-delivered newborn rats at time-intervals up to 3h after delivery after treatment of the neonatal rats with glucagon, dibutyryl cyclic AMP, cortisol or cortisol+dibutyryl cyclic AMP. Glycogenolysis was promoted by glucagon or dibutyryl cyclic AMP in the third hour after birth but not at earlier times. Cortisol and dibutyryl cyclic AMP together (but neither agent alone) promoted glycogenolysis in the second hour after birth, but no hormone combination was effective in the first postnatal hour. 2. The specific radioactivity of plasma d-glucose was measured as a function of time for up to 75 min after the intraperitoneal injection of d-[6-(14)C]glucose and d-[6-(3)H]glucose into newborn rats at delivery and after treatment with glucagon or actinomycin D. Glucagon-mediated hyperglycaemia at this time was due to an increased rate of glucose formation and a decreased rate of glucose utilization. Actinomycin D prevented glucose formation and accelerated the rate of postnatal hypoglycaemia. 3. The specific radioactivity of plasma l-lactate and the incorporation of (14)C into plasma d-glucose was measured as a function of time after the intraperitoneal injection of l-[U-(14)C]lactate into glucagon- or actinomycin D-treated rats immediately after delivery. The calculated rates of lactate formation were unchanged by either treatment, but lactate utilization was stimulated by glucagon administration. Glucagon stimulated and actinomycin D diminished (14)C incorporation into plasma d-glucose. 4. The factors involved in the initiation of glycogenolysis and gluconeogenesis in the rat immediately after birth are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357715"}
{"pmid": "4357712", "title": "Changes in enzyme activities in tissues of rats exposed to hypoxia.", "content": "Changes in enzyme activities in tissues of rats exposed to hypoxia. Rats were exposed to various degrees of hypoxia and enzyme activities in their tissues were determined. In general, oxidative metabolism was not increased in response to hypoxia, nor was anaerobic metabolism. Physiological and anatomical changes were concluded to be more important than changes in cellular enzyme activities in the overall adaptation to acute hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357712"}
{"pmid": "4357713", "title": "Cell-surface mucosubstances from trypsin diaggregation of normal and virus-transformed lines of baby-hamster kidney cells.", "content": "Cell-surface mucosubstances from trypsin diaggregation of normal and virus-transformed lines of baby-hamster kidney cells. Cell disaggregation by trypsin solubilizes significantly less mucosubstance from the surface of polyoma-virus-transformed baby-hamster kidney cells than from the same non-transformed cell line. The mucosubstance, which consists of both acid mucopolysaccharides and mucoproteins, also differs qualitatively in the two cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357713"}
{"pmid": "4357717", "title": "Hormonal regulation of glycogen metabolism in neonatal rat liver.", "content": "Hormonal regulation of glycogen metabolism in neonatal rat liver. 1. The development of active and inactive phosphorylase was determined in rat liver during the perinatal period. No inactive form could be found in tissues from animals less than 19 days gestation or older than the fifth postnatal day. 2. The regulation of phosphorylase in organ cultures of foetal rat liver was examined. None of the agents examined [glucagon, insulin or dibutyryl cyclic AMP (6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate)] changed the amount of phosphorylase activity. 3. Glycogen concentration in these explants were nevertheless decreased more than twofold by 4h of incubation with glucagon or dibutyryl cyclic AMP. Incubation with insulin for 4h increased the glycogen content twofold. 4. Glycogen synthetase activity was examined in these explants. I-form activity (without glucose 6-phosphate) was found to decrease by a factor of two after 4h of incubation with dibutyryl cyclic AMP, whereas I+D activity (with glucose 6-phosphate) remained nearly constant. Incubation for 4h with insulin increased I-form activity threefold, with only a slight increase in I+D activity. 5. When explants were incubated with insulin followed by addition of dibutyryl cyclic AMP, the effects of insulin on glycogen concentration and glycogen synthetase activity were reversed. 6. These results indicate that the regulation of glycogen synthesis may be the major factor in the hormonal control of glycogen metabolism in neonatal rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357717"}
{"pmid": "4357716", "title": "Microbial metabolism of amino alcohols. Metabolism of ethanolamine and 1-aminopropan-2-ol in species of Erwinia and the roles of amino alcohol kinase and amino alcohol o-phosphate phospho-lyase in aldehyde formation.", "content": "Microbial metabolism of amino alcohols. Metabolism of ethanolamine and 1-aminopropan-2-ol in species of Erwinia and the roles of amino alcohol kinase and amino alcohol o-phosphate phospho-lyase in aldehyde formation. 1. Growth of Erwinia carotovora N.C.P.P.B. 1280 on media containing 1-aminopropan-2-ol compounds or ethanolamine as the sole N source resulted in the excretion of propionaldehyde or acetaldehyde respectively. The inclusion of (NH(4))(2)SO(4) in media prevented aldehyde formation. 2. Growth, microrespirometric and enzymic evidence implicated amino alcohol O-phosphates as aldehyde precursors. An inducibly formed ATP-amino alcohol phosphotransferase was partially purified and found to be markedly stimulated by ADP, unaffected by NH(4) (+) ions and more active with ethanolamine than with 1-aminopropan-2-ol compounds. Amino alcohol O-phosphates were deaminated by an inducible phospho-lyase to give the corresponding aldehydes. This enzyme, separated from the kinase during purification, was more active with ethanolamine O-phosphate than with 1-aminopropan-2-ol O-phosphates. Activity of the phospho-lyase was unaffected by a number of possible effectors, including NH(4) (+) ions, but its formation was repressed by the addition of (NH(4))(2)SO(4) to growth media. 3. E. carotovora was unable to grow with ethanolamine or 1-aminopropan-2-ol compounds as sources of C, the production of aldehydes during utilization as N sources being attributable to the inability of the microbe to synthesize aldehyde dehydrogenase. 4. Of seven additional strains of Erwinia examined similar results were obtained only with Erwinia ananas (N.C.P.P.B. 441) and Erwinia milletiae (N.C.P.P.B. 955).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357716"}
{"pmid": "4357722", "title": "Adenosine metabolism in Micrococcus sodonensis.", "content": "Adenosine metabolism in Micrococcus sodonensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357722"}
{"pmid": "4357723", "title": "Pharmacologic and toxicologic studies with the polymyxins. I. A gas chromatographic procedure for the analysis of colistin in urine by its content of D-leucine.", "content": "Pharmacologic and toxicologic studies with the polymyxins. I. A gas chromatographic procedure for the analysis of colistin in urine by its content of D-leucine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357723"}
{"pmid": "4357724", "title": "Pharmacologic and toxicologic studies with the polymyxins. II. Comparative pharmnacologic studies of the sulfate and methanesulfonate salts of polymyxin B and colistin in dogs.", "content": "Pharmacologic and toxicologic studies with the polymyxins. II. Comparative pharmnacologic studies of the sulfate and methanesulfonate salts of polymyxin B and colistin in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357724"}
{"pmid": "4357725", "title": "Pharmacologic and toxicologic studies with the polymyxins. 3. Consideration regarding clinical use in dogs.", "content": "Pharmacologic and toxicologic studies with the polymyxins. 3. Consideration regarding clinical use in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357725"}
{"pmid": "4357727", "title": "Effects of mebutamate on the electroencephalographic sleep profile.", "content": "Effects of mebutamate on the electroencephalographic sleep profile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357727"}
{"pmid": "4357721", "title": "Interaction of Sendai virus with human erythrocytes. II. The fusion reactions.", "content": "Interaction of Sendai virus with human erythrocytes. II. The fusion reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357721"}
{"pmid": "4357720", "title": "Interaction of Sendai virus with human erythrocytes. I. The ultrastructure of untreated and pyridine-treated virions and their relationship with erythrocyte surface during hemagglutination.", "content": "Interaction of Sendai virus with human erythrocytes. I. The ultrastructure of untreated and pyridine-treated virions and their relationship with erythrocyte surface during hemagglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357720"}
{"pmid": "4357729", "title": "Elevation of plasma glucose levels by mammalian ACTH in the spiny dogfish shark (Squalus acanthias).", "content": "Elevation of plasma glucose levels by mammalian ACTH in the spiny dogfish shark (Squalus acanthias).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357729"}
{"pmid": "4357730", "title": "Effects of ACTH on the pituitary-interrenal axis and abundance of white blood cell types in juvenile coho salmon, Oncorhynchus kisutch.", "content": "Effects of ACTH on the pituitary-interrenal axis and abundance of white blood cell types in juvenile coho salmon, Oncorhynchus kisutch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357730"}
{"pmid": "4357731", "title": "Sodium-retaining bioassay of prolactin in the intact teleost Tilapia mossambica acclimated to sea water.", "content": "Sodium-retaining bioassay of prolactin in the intact teleost Tilapia mossambica acclimated to sea water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357731"}
{"pmid": "4357733", "title": "Cyclic adenosine 3':5'-monophosphate-dependent protein kinase.", "content": "Cyclic adenosine 3':5'-monophosphate-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357733"}
{"pmid": "4357732", "title": "Pituitary regulation of serum calcium levels in the killifish, Fundulus heteroclitus L.", "content": "Pituitary regulation of serum calcium levels in the killifish, Fundulus heteroclitus L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357732"}
{"pmid": "4357735", "title": "Kinetic studies of the activation of muscle phosphorylase phosphatase.", "content": "Kinetic studies of the activation of muscle phosphorylase phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357735"}
{"pmid": "4357734", "title": "Kinetic studies of the inhibition of muscle phosphorylase phosphatase.", "content": "Kinetic studies of the inhibition of muscle phosphorylase phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357734"}
{"pmid": "4357736", "title": "Alpha-keto acid dehydrogenase complexes. XX. A kinetic study of the pyruvate dehydrogenase complex from bovine kidney.", "content": "Alpha-keto acid dehydrogenase complexes. XX. A kinetic study of the pyruvate dehydrogenase complex from bovine kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357736"}
{"pmid": "4357737", "title": "Similarity of the active site of phosphorylation of the adenosine triphosphatase from transport of sodium and potassium ions in kidney to that for transport of calcium ions in the sarcoplasmic reticulum of muscle.", "content": "Similarity of the active site of phosphorylation of the adenosine triphosphatase from transport of sodium and potassium ions in kidney to that for transport of calcium ions in the sarcoplasmic reticulum of muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357737"}
{"pmid": "4357738", "title": "Human plasma high density lipoprotein. Interaction of the cyanogen bromide fragments from apolipoprotein glutamine II (A-II) with phosphatidylcholine.", "content": "Human plasma high density lipoprotein. Interaction of the cyanogen bromide fragments from apolipoprotein glutamine II (A-II) with phosphatidylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357738"}
{"pmid": "4357739", "title": "Antifreeze glycoprotein from an Antarctic fish. Effects of chemical modifications of carbohydrate residues on antifreeze and antilectin activities.", "content": "Antifreeze glycoprotein from an Antarctic fish. Effects of chemical modifications of carbohydrate residues on antifreeze and antilectin activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357739"}
{"pmid": "4357740", "title": "Concerted feedback inhibition. Purification and some properties of aspartokinase from Pseudomonas fluorescens.", "content": "Concerted feedback inhibition. Purification and some properties of aspartokinase from Pseudomonas fluorescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357740"}
{"pmid": "4357741", "title": "Concerted feedback inhibition. Modifier-induced oligomerization of the Pseudomonas fluorescens aspartokinase.", "content": "Concerted feedback inhibition. Modifier-induced oligomerization of the Pseudomonas fluorescens aspartokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357741"}
{"pmid": "4357742", "title": "Oxidation of 21-dehydrocorticosteroids to steroidal 20-Oxo-21-oic acids by an aldehyde dehydrogenase of sheep adrenal.", "content": "Oxidation of 21-dehydrocorticosteroids to steroidal 20-Oxo-21-oic acids by an aldehyde dehydrogenase of sheep adrenal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357742"}
{"pmid": "4357743", "title": "Studies on bovine hepatic fructose 1,6-diphosphatase. Substrate inhibition and the kinetic mechanism.", "content": "Studies on bovine hepatic fructose 1,6-diphosphatase. Substrate inhibition and the kinetic mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357743"}
{"pmid": "4357745", "title": "The development of a TRIC agent (Chlamydia trachomatis) and its associated polysaccharide in suspended cell cultures.", "content": "The development of a TRIC agent (Chlamydia trachomatis) and its associated polysaccharide in suspended cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357745"}
{"pmid": "4357746", "title": "Interaction between viruses and platelets: requirement of haemolytic activity for platelet aggregation induced by paramyxoviruses.", "content": "Interaction between viruses and platelets: requirement of haemolytic activity for platelet aggregation induced by paramyxoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357746"}
{"pmid": "4357744", "title": "Chicken liver phosphofructokinase. II. Cold inactivation.", "content": "Chicken liver phosphofructokinase. II. Cold inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357744"}
{"pmid": "4357748", "title": "Synthesis of ribonucleic acids in KB cells infected with rhinovirus type 14.", "content": "Synthesis of ribonucleic acids in KB cells infected with rhinovirus type 14.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357748"}
{"pmid": "4357747", "title": "Characterization of temperature-sensitive mutants of SV40.", "content": "Characterization of temperature-sensitive mutants of SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357747"}
{"pmid": "4357750", "title": "Homology of surface receptors for poliovirus on mammalian cell lines.", "content": "Homology of surface receptors for poliovirus on mammalian cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357750"}
{"pmid": "4357749", "title": "The effect of rifampicin, actinomycin D and mitomycin C on poliovirus and foot-and-mouth disease virus replication.", "content": "The effect of rifampicin, actinomycin D and mitomycin C on poliovirus and foot-and-mouth disease virus replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357749"}
{"pmid": "4357751", "title": "Inhibition by interferon of polyoma virus-induced cell DNA synthesis in mouse peritoneal macrophages.", "content": "Inhibition by interferon of polyoma virus-induced cell DNA synthesis in mouse peritoneal macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357751"}
{"pmid": "4357753", "title": "The lipid content of two iridescent viruses.", "content": "The lipid content of two iridescent viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357753"}
{"pmid": "4357752", "title": "The distribution of virus proteins in BHK 21 cells infected with vesicular stomatitis virus (Indiana C).", "content": "The distribution of virus proteins in BHK 21 cells infected with vesicular stomatitis virus (Indiana C).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357752"}
{"pmid": "4357754", "title": "The morphology, morphogenesis, and serological characterization of the rhabdoviruses Navarro, Kwatta, and Mossuril.", "content": "The morphology, morphogenesis, and serological characterization of the rhabdoviruses Navarro, Kwatta, and Mossuril.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357754"}
{"pmid": "4357755", "title": "Cytochalasin B-induced activation in the synthesis of L-cell virus particles.", "content": "Cytochalasin B-induced activation in the synthesis of L-cell virus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357755"}
{"pmid": "4357756", "title": "Characterization of segmented double-helical RNA from bacteriophage phi6.", "content": "Characterization of segmented double-helical RNA from bacteriophage phi6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357756"}
{"pmid": "4357757", "title": "A human cell line from a pleural effusion derived from a breast carcinoma.", "content": "A human cell line from a pleural effusion derived from a breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357757"}
{"pmid": "4357759", "title": "Case-control study of Hodgkin's disease. II. Herpesvirus group antibody titers and HL-A type.", "content": "Case-control study of Hodgkin's disease. II. Herpesvirus group antibody titers and HL-A type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357759"}
{"pmid": "4357758", "title": "In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors.", "content": "In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357758"}
{"pmid": "4357760", "title": "Limited capacity for motor activity as a cause for declining food intake in cancer.", "content": "Limited capacity for motor activity as a cause for declining food intake in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357760"}
{"pmid": "4357761", "title": "In vivo and in vitro studies on the morphogenesis of tumors induced by murine sarcoma virus (Harvey).", "content": "In vivo and in vitro studies on the morphogenesis of tumors induced by murine sarcoma virus (Harvey).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357761"}
{"pmid": "4357762", "title": "Combined neoplastic effects of vaccinia virus and 3-methylcholanthrene. 3. Susceptibility and resistance in transplanted mouse skin.", "content": "Combined neoplastic effects of vaccinia virus and 3-methylcholanthrene. 3. Susceptibility and resistance in transplanted mouse skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357762"}
{"pmid": "4357763", "title": "Analysis by immunoelectron microscopy of type-C viruses associated with primary and short-term transplanted mouse plasma cell tumors.", "content": "Analysis by immunoelectron microscopy of type-C viruses associated with primary and short-term transplanted mouse plasma cell tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357763"}
{"pmid": "4357764", "title": "Malignant mouse-liver tumors resembling human hepatoblastomas.", "content": "Malignant mouse-liver tumors resembling human hepatoblastomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357764"}
{"pmid": "4357765", "title": "Enzyme activities and extrinsic proteins in plasma membranes from normal liver and Morris hepatoma 5123tc.", "content": "Enzyme activities and extrinsic proteins in plasma membranes from normal liver and Morris hepatoma 5123tc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357765"}
{"pmid": "4357766", "title": "Comparison of three mammary tumor viruses in genetically similar susceptible mice.", "content": "Comparison of three mammary tumor viruses in genetically similar susceptible mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357766"}
{"pmid": "4357767", "title": "Quantitative lung colony assay for tumor immunity in mice.", "content": "Quantitative lung colony assay for tumor immunity in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357767"}
{"pmid": "4357768", "title": "Acute alcoholic myopathy. Enzyme histochemistry and electron microscopic findings.", "content": "Acute alcoholic myopathy. Enzyme histochemistry and electron microscopic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357768"}
{"pmid": "4357769", "title": "Sural nerve conduction velocity in peripheral neuropathies and subacute myelo-optico-neuropathies (SMON).", "content": "Sural nerve conduction velocity in peripheral neuropathies and subacute myelo-optico-neuropathies (SMON).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357769"}
{"pmid": "4357771", "title": "Cyclic nucleotides as intracellular mediators of the expression of antigen-sensitive cells.", "content": "Cyclic nucleotides as intracellular mediators of the expression of antigen-sensitive cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357771"}
{"pmid": "4357772", "title": "Phagocytic release and activation of human leukocyte procollagenase.", "content": "Phagocytic release and activation of human leukocyte procollagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357772"}
{"pmid": "4357776", "title": "Psycho-analytic group interview and short-term group psychotherapy with post-myocardial infarction patients.", "content": "Psycho-analytic group interview and short-term group psychotherapy with post-myocardial infarction patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357776"}
{"pmid": "4357783", "title": "A sensitive in vitro bioassay method for luteinizing hormone (LH) activity.", "content": "A sensitive in vitro bioassay method for luteinizing hormone (LH) activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357783"}
{"pmid": "4357784", "title": "Stimulating effect of dibutyryl cyclic adenosine 3',5' monophosphate on protein synthesis in a thyroidal cell-free system at low potassium and sodium concentrations.", "content": "Stimulating effect of dibutyryl cyclic adenosine 3',5' monophosphate on protein synthesis in a thyroidal cell-free system at low potassium and sodium concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357784"}
{"pmid": "4357787", "title": "Phagocytosis of supernumerary spermatozoa by two-cell embryos.", "content": "Phagocytosis of supernumerary spermatozoa by two-cell embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357787"}
{"pmid": "4357786", "title": "Fine structure of the urinary bladder of the bullfrog. (Rana catesbiana).", "content": "Fine structure of the urinary bladder of the bullfrog. (Rana catesbiana).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357786"}
{"pmid": "4357788", "title": "Bacterial endophthalmitis after cataract extraction. II. Incidence in 36,000 consecutive operations with special reference to preoperative topical antibiotics.", "content": "Bacterial endophthalmitis after cataract extraction. II. Incidence in 36,000 consecutive operations with special reference to preoperative topical antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357788"}
{"pmid": "4357785", "title": "Freeze-fracture studies of gap junctions of normal and neoplastic astrocytes.", "content": "Freeze-fracture studies of gap junctions of normal and neoplastic astrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357785"}
{"pmid": "4357789", "title": "Collagenase inhibitors in Pseudomonas keratitis. Adjuncts to antibiotic therapy in rabbits.", "content": "Collagenase inhibitors in Pseudomonas keratitis. Adjuncts to antibiotic therapy in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357789"}
{"pmid": "4357790", "title": "Viral isolate in superficial punctate keratitis.", "content": "Viral isolate in superficial punctate keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357790"}
{"pmid": "4357791", "title": "Adaptive response of hepatic carbohydrate metabolism to oral administration of p,p'-1,1,1-trichloro-2,2-bis (p-chlorophenyl)ethane in rats.", "content": "Adaptive response of hepatic carbohydrate metabolism to oral administration of p,p'-1,1,1-trichloro-2,2-bis (p-chlorophenyl)ethane in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357791"}
{"pmid": "4357793", "title": "Inhibition of purine biosynthesis de novo in sarcoma 180 ascites cells by mercapto and seleno purine analogs.", "content": "Inhibition of purine biosynthesis de novo in sarcoma 180 ascites cells by mercapto and seleno purine analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357793"}
{"pmid": "4357792", "title": "Vitamin C--effects on the Na+, K+ adenosine triphosphate phosphohydrolase complexes of several tissues.", "content": "Vitamin C--effects on the Na+, K+ adenosine triphosphate phosphohydrolase complexes of several tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357792"}
{"pmid": "4357795", "title": "Effect of cyclic nucleotides on activity of cyclic 3',5'-adenosine monophosphate phosphodiesterase.", "content": "Effect of cyclic nucleotides on activity of cyclic 3',5'-adenosine monophosphate phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357795"}
{"pmid": "4357794", "title": "Action of organophosphorus compounds on cell organelles. I. Effect of tetraethyl dithio pyrophosphate on lysosomal hydrolases.", "content": "Action of organophosphorus compounds on cell organelles. I. Effect of tetraethyl dithio pyrophosphate on lysosomal hydrolases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357794"}
{"pmid": "4357797", "title": "Leukopenia, leukoagglutinins, and low IgM in a family with severe febrile illnesses.", "content": "Leukopenia, leukoagglutinins, and low IgM in a family with severe febrile illnesses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357797"}
{"pmid": "4357798", "title": "Studies of the Epstein-Barr virus-host relationship: autochthonous and allogeneic lymphocyte stimulation by lymphoblast cell lines in mixed cell culture.", "content": "Studies of the Epstein-Barr virus-host relationship: autochthonous and allogeneic lymphocyte stimulation by lymphoblast cell lines in mixed cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357798"}
{"pmid": "4357799", "title": "Identification and partial characterization of specific estrogen receptors in the vole (Microtus montanus).", "content": "Identification and partial characterization of specific estrogen receptors in the vole (Microtus montanus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357799"}
{"pmid": "4357800", "title": "Species specificity of the inhibition of adenylate cyclase activation by products of ACTH-stimulated fat cells.", "content": "Species specificity of the inhibition of adenylate cyclase activation by products of ACTH-stimulated fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357800"}
{"pmid": "4357801", "title": "The lactate dehydrogenase system in the heart and skeletal muscle of fish: a comparative study.", "content": "The lactate dehydrogenase system in the heart and skeletal muscle of fish: a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357801"}
{"pmid": "4357802", "title": "Phosphatase activity in epiphyseal cartilage of the chicken (Gallus gallus).", "content": "Phosphatase activity in epiphyseal cartilage of the chicken (Gallus gallus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357802"}
{"pmid": "4357804", "title": "A spin-label study of horse erythrocyte carbonic anhydrases C and D.", "content": "A spin-label study of horse erythrocyte carbonic anhydrases C and D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357804"}
{"pmid": "4357803", "title": "Effects of estradiol and testosterone on the immature female chicken (Gallus domesticus). II. Immunodiffusional patterns of yolk lipoproteins in the liver and plasma.", "content": "Effects of estradiol and testosterone on the immature female chicken (Gallus domesticus). II. Immunodiffusional patterns of yolk lipoproteins in the liver and plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357803"}
{"pmid": "4357805", "title": "Metabolism in porifera. II. Distribution of sterols.", "content": "Metabolism in porifera. II. Distribution of sterols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357805"}
{"pmid": "4357806", "title": "Pathogenesis of genetic diabetes mellitus: further development of a hypothesis.", "content": "Pathogenesis of genetic diabetes mellitus: further development of a hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357806"}
{"pmid": "4357807", "title": "In vitro biosynthesis of human placental lactogen (HPL) by chorionic tissue and the diagnostic value of HPL in trophoblastic disease.", "content": "In vitro biosynthesis of human placental lactogen (HPL) by chorionic tissue and the diagnostic value of HPL in trophoblastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357807"}
{"pmid": "4357808", "title": "Radiation myelopathy.", "content": "Radiation myelopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357808"}
{"pmid": "4357810", "title": "Protein kinase and cyclic AMP-binding activities in liver and adipose tissue of normal, streptozotocin-diabetic and adrenalectomized rats.", "content": "Protein kinase and cyclic AMP-binding activities in liver and adipose tissue of normal, streptozotocin-diabetic and adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357810"}
{"pmid": "4357809", "title": "Pathohistological findings in the peripheral nervous system (nn. ischiadici) after experimental carbon tetrachloride intoxication in bastard rabbits.", "content": "Pathohistological findings in the peripheral nervous system (nn. ischiadici) after experimental carbon tetrachloride intoxication in bastard rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357809"}
{"pmid": "4357811", "title": "Sequence analysis of polyribonucleotides by continuous directional degradation--a study of the course of the reaction at nucleotide concentrations between 10-7 and 10-5 molar.", "content": "Sequence analysis of polyribonucleotides by continuous directional degradation--a study of the course of the reaction at nucleotide concentrations between 10-7 and 10-5 molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357811"}
{"pmid": "4357813", "title": "Evaluation of the energetics of cytochrome C oxidase in the absense of cytochrome C.", "content": "Evaluation of the energetics of cytochrome C oxidase in the absense of cytochrome C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357813"}
{"pmid": "4357812", "title": "Biosynthesis of sideramines in fungi. Fusigen synthetase from extracts of Fusarium cubense.", "content": "Biosynthesis of sideramines in fungi. Fusigen synthetase from extracts of Fusarium cubense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357812"}
{"pmid": "4357814", "title": "Poly (ADP-ribose) glycohydrolase in mouse fibroblast cells (LS cells).", "content": "Poly (ADP-ribose) glycohydrolase in mouse fibroblast cells (LS cells).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357814"}
{"pmid": "4357815", "title": "The inhibition of Azotobacter vinelandii terminal oxidases by cyanide.", "content": "The inhibition of Azotobacter vinelandii terminal oxidases by cyanide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357815"}
{"pmid": "4357816", "title": "Improvement of the spin-labelling technique by the use of a radioactive spin label.", "content": "Improvement of the spin-labelling technique by the use of a radioactive spin label.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357816"}
{"pmid": "4357818", "title": "Pyruvate metabolism and nitrogen fixation in Azotobacter.", "content": "Pyruvate metabolism and nitrogen fixation in Azotobacter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357818"}
{"pmid": "4357817", "title": "Two ACTH species in rat pituitary gland.", "content": "Two ACTH species in rat pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357817"}
{"pmid": "4357820", "title": "Solid-phase Edman degradation of a protein: N-terminal sequence of cytochrome c from Candida krusei.", "content": "Solid-phase Edman degradation of a protein: N-terminal sequence of cytochrome c from Candida krusei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357820"}
{"pmid": "4357819", "title": "Novel type of catabolite repression in the pathway of gamma-aminobutyrate breakdown in Escherichia coli K-12.", "content": "Novel type of catabolite repression in the pathway of gamma-aminobutyrate breakdown in Escherichia coli K-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357819"}
{"pmid": "4357822", "title": "Cytochromes of two methane-utilizing bacteria.", "content": "Cytochromes of two methane-utilizing bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357822"}
{"pmid": "4357821", "title": "Stimulation of adipose tissue triglyceride lipase activity after in vivo administration of dibutyryl cyclic AMP or norepinephrine.", "content": "Stimulation of adipose tissue triglyceride lipase activity after in vivo administration of dibutyryl cyclic AMP or norepinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357821"}
{"pmid": "4357823", "title": "The solid-phase synthesis of human and monkey beta-melanotropins.", "content": "The solid-phase synthesis of human and monkey beta-melanotropins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357823"}
{"pmid": "4357824", "title": "A preparative method for the isolation of carboxyl terminal tryptic peptides from proteins.", "content": "A preparative method for the isolation of carboxyl terminal tryptic peptides from proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357824"}
{"pmid": "4357826", "title": "Effects of synthetic ACTH on corticosteroid-induced growth suppression.", "content": "Effects of synthetic ACTH on corticosteroid-induced growth suppression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357826"}
{"pmid": "4357827", "title": "Plasma-cell mastitis: case report.", "content": "Plasma-cell mastitis: case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357827"}
{"pmid": "4357825", "title": "Cyclic AMP metabolism in asthma: studies with leukocytes and lymphocytes.", "content": "Cyclic AMP metabolism in asthma: studies with leukocytes and lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357825"}
{"pmid": "4357828", "title": "Muscle fiber type, rigor development and bone strength in dobule muscled cattle.", "content": "Muscle fiber type, rigor development and bone strength in dobule muscled cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357828"}
{"pmid": "4357829", "title": "Metabolic pathways of biuret degradation and formation of a biuret-complex in the rumen.", "content": "Metabolic pathways of biuret degradation and formation of a biuret-complex in the rumen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357829"}
{"pmid": "4357831", "title": "Letter: Optimal postfixation washing time for ultrastructural demonstration of glucose 6-phosphatase activity.", "content": "Letter: Optimal postfixation washing time for ultrastructural demonstration of glucose 6-phosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357831"}
{"pmid": "4357830", "title": "Metabolism of biuret by ruminants: in vivo and in vitro studies and the role of protozoa in biuretolysis.", "content": "Metabolism of biuret by ruminants: in vivo and in vitro studies and the role of protozoa in biuretolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357830"}
{"pmid": "4357832", "title": "Conformation of coenzyme fragments when bound to lactate dehydrogenase.", "content": "Conformation of coenzyme fragments when bound to lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357832"}
{"pmid": "4357833", "title": "Fine structure of the contractile vacuole pore in Paramecium.", "content": "Fine structure of the contractile vacuole pore in Paramecium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357833"}
{"pmid": "4357834", "title": "Breeding of European hamsters.", "content": "Breeding of European hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357834"}
{"pmid": "4357835", "title": "Establishment by selective inbreeding of the IVCS strain and related sister strains of the mouse, demonstrating regularly repeated 4-day estrous cycles.", "content": "Establishment by selective inbreeding of the IVCS strain and related sister strains of the mouse, demonstrating regularly repeated 4-day estrous cycles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357835"}
{"pmid": "4357836", "title": "Simian virus 16 associated with an epizootic of obscure neurologic disease.", "content": "Simian virus 16 associated with an epizootic of obscure neurologic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357836"}
{"pmid": "4357838", "title": "Maintenance and husbandry of armadillo colonies.", "content": "Maintenance and husbandry of armadillo colonies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357838"}
{"pmid": "4357837", "title": "Preventive medicine in anthropoids: parasite control.", "content": "Preventive medicine in anthropoids: parasite control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357837"}
{"pmid": "4357840", "title": "The pathogenesis of the alopecia due to hair-chewing in mice.", "content": "The pathogenesis of the alopecia due to hair-chewing in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357840"}
{"pmid": "4357839", "title": "Humoral immune response of the adult chinchilla.", "content": "Humoral immune response of the adult chinchilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357839"}
{"pmid": "4357841", "title": "Protein requirement of growing gerbils.", "content": "Protein requirement of growing gerbils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357841"}
{"pmid": "4357842", "title": "Establishment of a helminth-free opossum colony.", "content": "Establishment of a helminth-free opossum colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357842"}
{"pmid": "4357843", "title": "An epizootic of protozoan enteritis in a closed mouse colony.", "content": "An epizootic of protozoan enteritis in a closed mouse colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357843"}
{"pmid": "4357844", "title": "Blood acid-base status in normal albino rats.", "content": "Blood acid-base status in normal albino rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357844"}
{"pmid": "4357845", "title": "A durable housing facility for reptiles.", "content": "A durable housing facility for reptiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357845"}
{"pmid": "4357846", "title": "An apparatus for anesthetizing small laboratory rodents.", "content": "An apparatus for anesthetizing small laboratory rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357846"}
{"pmid": "4357847", "title": "Pediculosis of spider monkeys: a case report with zoonotic implications.", "content": "Pediculosis of spider monkeys: a case report with zoonotic implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357847"}
{"pmid": "4357848", "title": "Versatile cage for environmental protection housing of research animals.", "content": "Versatile cage for environmental protection housing of research animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357848"}
{"pmid": "4357850", "title": "A combination sterilizing chamber and transfer and housing isolator for use in gnotobiotic laboratories.", "content": "A combination sterilizing chamber and transfer and housing isolator for use in gnotobiotic laboratories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357850"}
{"pmid": "4357849", "title": "Measurement of blood cholinesterase activity in laboratory animals utilizing dimethylbutyl acetate as a substrate.", "content": "Measurement of blood cholinesterase activity in laboratory animals utilizing dimethylbutyl acetate as a substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357849"}
{"pmid": "4357851", "title": "Indirect measurement of arterial blood pressure in the laboratory pony.", "content": "Indirect measurement of arterial blood pressure in the laboratory pony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357851"}
{"pmid": "4357852", "title": "Hematologic changes to 60 days of age in clinically normal beagles.", "content": "Hematologic changes to 60 days of age in clinically normal beagles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357852"}
{"pmid": "4357854", "title": "A case of conjoined twins in the Sprague-Dawley rat.", "content": "A case of conjoined twins in the Sprague-Dawley rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357854"}
{"pmid": "4357853", "title": "Microbial flora and viral contact status of Chinese hamsters (Cricetulus griseus).", "content": "Microbial flora and viral contact status of Chinese hamsters (Cricetulus griseus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357853"}
{"pmid": "4357856", "title": "The Epstein-Barr virus carrier state in infectious mononucleosis.", "content": "The Epstein-Barr virus carrier state in infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357856"}
{"pmid": "4357855", "title": "Pathogenesis of hereditary vitamin-D-dependent rickets. An inborn error of vitamin D metabolism involving defective conversion of 25-hydroxyvitamin D to 1 alpha,25-dihydroxyvitamin D.", "content": "Pathogenesis of hereditary vitamin-D-dependent rickets. An inborn error of vitamin D metabolism involving defective conversion of 25-hydroxyvitamin D to 1 alpha,25-dihydroxyvitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357855"}
{"pmid": "4357857", "title": "Strand orientation of SV40 transcription in cells infected by non-defective adenovirus 2-SV40 hybrid viruses.", "content": "Strand orientation of SV40 transcription in cells infected by non-defective adenovirus 2-SV40 hybrid viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357857"}
{"pmid": "4357858", "title": "Morphine blockade of amino acid putative transmitters on cat spinal cord sensory interneurones.", "content": "Morphine blockade of amino acid putative transmitters on cat spinal cord sensory interneurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357858"}
{"pmid": "4357860", "title": "Effect of aminoglutethimide and glutethimide on the pituitary-adrenal system.", "content": "Effect of aminoglutethimide and glutethimide on the pituitary-adrenal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357860"}
{"pmid": "4357862", "title": "Suppression of pituitary-adrenal activity and shock-induced fighting in rats.", "content": "Suppression of pituitary-adrenal activity and shock-induced fighting in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357862"}
{"pmid": "4357861", "title": "Adrenocortical influences upon the extinction of an appetitive runway response.", "content": "Adrenocortical influences upon the extinction of an appetitive runway response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357861"}
{"pmid": "4357863", "title": "Hydration releases inhibition of feeding produced by intracranial angiotensin.", "content": "Hydration releases inhibition of feeding produced by intracranial angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357863"}
{"pmid": "4357865", "title": "Homology between type-C viruses of various species as determined by molecular hybridization.", "content": "Homology between type-C viruses of various species as determined by molecular hybridization. Two strains of feline leukemia virus, two endogenous feline type-C viruses (RD/CCC group), several endogenous and laboratory strains of murine \"leukemia\" virus, two rat viruses, two primate viruses (woolly monkey and gibbon ape), as well as hamster, pig, and avian type-C viruses were examined for their relatedness to one another by molecular hybridization. The extent of nucleic-acid homology was determined by hybridization of the various viral RNAs to a [(3)H]DNA product synthesized from each virus. Among the murine type-C viruses (Rauscher, Kirsten, AT-124, and endogenous BALB/c virus) a high degree of homology is observed, although the viruses are not identical. The two primate viruses are also closely related to one another. The feline, rat, hamster, and pig endogenous viruses can be readily distinguished from one another and from the murine and primate viruses since their DNA products share very little or no nucleic-acid homology. However, the murine and primate type-C virus groups possess a surprising degree of relatedness. Feline type-C viruses fall into two distinct groups, the feline leukemia virus group and the RD-114/CCC group, with little detectable nucleic-acid homology between them. Infection of feline or rat cells with type-C virus results in production of the endogenous type-C virus of the species along with the infecting virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357865"}
{"pmid": "4357859", "title": "Electrophysiological investigation of natural sleep and waking in turtles and hens.", "content": "Electrophysiological investigation of natural sleep and waking in turtles and hens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357859"}
{"pmid": "4357867", "title": "Specific photoaffinity labeling of the adenosine 3':5'-cyclic monophosphate receptor in intact ghosts from human erythrocytes.", "content": "Specific photoaffinity labeling of the adenosine 3':5'-cyclic monophosphate receptor in intact ghosts from human erythrocytes. [(3)H]N(6)-(Ethyl 2-diazomalonyl)-adenosine 3':5'-cyclic monophosphate is incorporated into intact ghosts from human erythrocytes on photolysis at 253.7 nm. Incorporation is blocked in the presence of adenosine 3':5'-cyclic monophosphate (cyclic AMP) and does not occur in the absence of irradiation. Sodium dodecyl sulfate disc gel electrophoresis of solubilized ghosts shows that one protein is labeled. The position of this protein on the gel corresponds exactly to that previously found. [J. Biol. Chem. 247, 8145 (1972)] for the endogeneous protein substrate of the endogenous, cyclic AMP-dependent, protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357867"}
{"pmid": "4357864", "title": "In vitro translation of oogenetic messenger RNA of sea urchin eggs and picornavirus RNA with a cell-free system from sarcoma 180.", "content": "In vitro translation of oogenetic messenger RNA of sea urchin eggs and picornavirus RNA with a cell-free system from sarcoma 180. A cell-free protein-synthesizing system prepared from mouse sarcoma 180 was characterized by use of RNA from mengo virus and sea urchin egg. In the presence of exogenous mammalian transfer RNA, total sea urchin egg RNA and mengo RNA direct incorporation of [(3)H]leucine into acid-insoluble material. The system is extremely efficient in that a stimulation of 100-times over background can be obtained. Studies with formylmethionyl-transfer RNA, as well as with inhibitors of initiation, indicate that multiple initiation occurs; further, 85-90% of all chains made in vitro are subsequently released from ribosomes. An average translation time of 3.5 min was determined with messenger RNA of sea urchin egg, and product analysis indicates that high-molecular-weight products (greater than 50,000 molecular weight) are being made in vitro. Sequences of sea urchin egg RNA containing poly(A) act as messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357864"}
{"pmid": "4357868", "title": "Direct evidence of the C-like form of sodium deoxyribonucleate.", "content": "Direct evidence of the C-like form of sodium deoxyribonucleate. From infrared linear dichroism studies, direct evidence is given for a new Na DNA form, which is similar to the C form of Li DNA. This C-like form in Na DNA occurs under conditions of very low NaCl content (at high relative humidity), high NaCl content (at low relative humidity), and low G + C content of the DNA (at low relative humitiy). The C form of Li DNA was originally discovered by x-ray diffraction, but has not previously been characterized by infrared spectroscopy. The C form is primarily characterized by the orientation of the O2- -O3 line of the phosphate group, which is about 48 degrees (+/-2 degrees ) with respect to the helical DNA axis and which is different from that of the B and A forms. Na DNA molecules rich in A + T may entirely or partially adopt the C form at low relative humidity. Since from infrared evidence, the C-like form is found not only in Li DNA at low relative humidity but also in Na DNA under different conditions, the C form may be biologically important. A possible role for recognition by proteins is suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357868"}
{"pmid": "4357866", "title": "Altered growth behavior of malignant cells associated with changes in externally labeled glycoprotein and glycolipid.", "content": "Altered growth behavior of malignant cells associated with changes in externally labeled glycoprotein and glycolipid. By use of galactose oxidase (EC 1.1.3.9), followed by reduction with tritiated sodium borohydride, the surface structures of transformed 3T3 and NIL cells, under ordinary growth conditions, were characterized by (i) deletion of the normally existing glycoprotein label and (ii) appearance or increase of a new glycoprotein label. NIL cells had a galactoprotein label with molecular weight 200,000 that was deleted in NIL cells transformed by polyoma virus. 3T3 cells had a glycoprotein label with molecular weight of 30,000 that was lost after transformation. Glycoproteins of transformed 3T3 cells, with molecular weight 105,000, and those of transformed NIL cells, with molecular weight 85,000, were not labeled in normal confluent cells, but became labeled after trypsin treatment. The label in glycolipids was quantitatively different in normal and transformed cells. The labeling pattern in glycoprotein and glycolipids of transformed NIL and 3T3 cells became similar to that of nontransformed cells when contact responses of transformed cells became conspicuous when cells were cultured in the presence of dextran sulfate or dibutyryl cyclic adenosine monophosphate, or in medium in which glucose was replaced with galactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357866"}
{"pmid": "4357869", "title": "Inhibitory action of Ruthenium red on neuromuscular transmission.", "content": "Inhibitory action of Ruthenium red on neuromuscular transmission. The effect of Ruthenium Red on synaptic transmission was examined at isolated junctions of the frog, by conventional methods for stimulation and intracellular recording. Ruthenium Red (2.5-10.0 muM) reduces the synaptic potential to subthreshold levels. An analysis of this phenomenon shows that the main action of Ruthenium Red is on the presynaptic nerve terminal where it decreases the number of quanta of transmitter liberated by the nerve impulse. It has the following additional effects: a reduction in the amplitude of the spontaneous miniature end plate potentials; an increase in their frequency; and an increase in delayed release of transmitter after a nerve impulse. Some of these results are discussed in terms of the known inhibitory action of Ruthenium Red on calcium transport across mitochondrial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357869"}
{"pmid": "4357870", "title": "Nuclear binding of steroid receptors: comparison in intact cells and cell-free systems.", "content": "Nuclear binding of steroid receptors: comparison in intact cells and cell-free systems. In regulating gene expression in mammalian tissues, steroid hormones bind to cytoplasmic receptors and the resulting complex associates with the nucleus. In an attempt to study this nuclear association under more precisely controlled conditions, we examined the binding of receptor-[(3)H]steroid complexes to isolated nuclei. Two systems were used: the glucocorticoid-responsive hepatoma cell and the estrogen-sensitive immature rat uterus. Cell-free nuclear binding resembles that observed in the intact cell; it requires the receptor-steroid complex in the appropriate form (\"active\" complex); it is of high affinity; and it appears to involve about 4000 nuclear acceptor sites per haploid genome. Furthermore, whether binding occurs in intact cells or in cell-free extracts, complexes dissociate from nuclei at similar rates, and the ability of NaCl to extract either type of nuclear-bound complex and the sedimentation velocities of the extracted complexes are identical. Despite these similarities, acceptor sites detected in isolated nuclei differ from those of intact cells, since in neither hepatoma cells nor in the uterus do complexes bound to the nuclei of intact cells prevent further cell-free binding. We conclude that receptor-steroid complexes bind to acceptor sites in isolated nuclei that are chemically similar to, but topographically different from, those of the intact cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357870"}
{"pmid": "4357871", "title": "Regulation of hepatic glycogen synthesis during fetal development: roles of hydrocortisone, insulin, and insulin receptors.", "content": "Regulation of hepatic glycogen synthesis during fetal development: roles of hydrocortisone, insulin, and insulin receptors. In fetal rat liver in utero, an increase in glycogen and the glycogen synthetic enzyme glycogen synthetase (EC 2.4.1.11) occurs between gestational days 17 and 19. We used an organ culture system for finding the stimulus for increased enzyme activity and defining the relationship of this increase to glycogen synthesis. In fetal-liver explants from an earlier period (gestational day 16), hydrocortisone causes an elevation in total glycogen synthetase activity. This effect, which can be blocked by actinomycin D, is strikingly similar in time course and magnitude to the normal increase in utero. However, in order for glycogen synthesis to proceed after hydrocortisone increases glycogen synthetase levels, insulin is required. Unlike hydrocortisone, insulin does not increase total glycogen synthetase; it appears to act by converting the b or phospho form of synthetase to the a or dephospho form. Insulin alone does not stimulate glycogen synthesis in explants from 16-day fetal liver, although no defect in insulin binding was demonstrable. These findings support the hypothesis that the increase in liver-glycogen synthesis during the last trimester requires glucocorticoids for the developmental induction of glycogen synthetase and insulin for activation of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357871"}
{"pmid": "4357872", "title": "Thyroid hormone action in cell culture: domonstration of nuclear receptors in intact cells and isolated nuclei.", "content": "Thyroid hormone action in cell culture: domonstration of nuclear receptors in intact cells and isolated nuclei. Triiodothyronine and thyroxine induce a 3-fold increase in the rate of growth of GH(1) cells in culture. To study further the action of these hormones, we examined the binding of [(125)I]triiodothyronine and purified [(125)I]thyroxine to cellular fractions after incubation with intact cells in serum-free medium. High-affinity, low-capacity binding sites for the hormones were demonstrated in nuclear but not in mitochondrial or cytosol fractions. Chromatographic analysis of the bound nuclear radioactivity from cells incubated with [(125)I]thyroxine demonstrated 97% thyroxine, 1% iodide, and 1% triiodothyronine. Apparent equilibrium dissociation constants, determined by Scatchard analysis, were 29 pM for triidothyronine and 260 pM for thyroxine. The maximal binding capacity was identical for both hormones, with about 5000 sites per cell nucleus. [(125)I]Thyroxine binding was competitively inhibited by triiodothyronine. These data suggest that triiodothyronine and thyroxine interact with identical nuclear receptors, and that conversion of thyroxine to triiodothyronine may not be a prerequisite for biologic activity. Similar high-affinity, low-capacity nuclear binding sites were also demonstrated by incubation of [(125)I]triidothyronine directly with isolated nuclei. Incubation of cells with increasing concentrations of nonradioactive triidothyronine results in a subsequent increase in binding when [(125)I]triiodothyronine is then incubated directly with isolated nuclei. This result suggests that nuclear receptors are not fixed, but increase after exposure of intact cells to hormone. This increase in nuclear receptor content may result from the transfer of an unstable cytosol receptor to the nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357872"}
{"pmid": "4357873", "title": "Isolation of defective mutant of avian sarcoma virus.", "content": "Isolation of defective mutant of avian sarcoma virus. A colony of transformed cells was isolated from chick-embryo cells infected with a stock of nondefective Schmidt-Ruppin strain of Rous sarcoma virus. The virus recovered from this colony was a stable defective mutant very similar to the Bryan strain of Rous sarcoma virus in the following characteristics: (i) noninfectiousness of virus particles released from transformed cells that lack helper factor; (ii) formation of infectious pseudotypes by coinfection with avian leukosis virus or by interaction with endogenous-helper factor in chicken cells; (iii) ability of the noninfectious form of virus to transform chick-embryo cells in the presence of ultraviolet light-inactivated Sendai virus; (iv) absence of glycoprotein in the noninfectious form; (v) failure to produce nondefective virus by recombination with avian leukosis virus; and (vi) segregation of polymerase-negative virus. The morphology of transformed cells is characteristic of those infected by the Schmidt-Ruppin strain. The demonstration of segregation of such a defective virus from nondefective sarcoma virus and failure to detect revertants of this mutant suggest that the deletion of some genes may be involved in this mutation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357873"}
{"pmid": "4357874", "title": "Requirement of a phage-induced 5'-exonuclease for the expression of late genes of bacteriophage T5.", "content": "Requirement of a phage-induced 5'-exonuclease for the expression of late genes of bacteriophage T5. Amber mutants of bacteriophage T5 defective in gene D15, which codes for a 5'-exonuclease, do not express late genes. Electrophoretic separation in sodium dodecyl sulfate-polyacrylamide gels of the proteins induced by this mutant in nonpermissive Escherichia coli show a virtual absence of late proteins. Synthesis of lysozyme and serum-blocking power is very low whereas the extent of synthesis of an early enzyme, deoxyribonucleoside monophosphokinase, is similar to that in wild-type infections. It is proposed that one requirement for the expression of late T5 genes is the introduction of gaps or nicks in the T5 DNA so that late transcription can occur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357874"}
{"pmid": "4357875", "title": "In vitro transcription of the viral-specific sequences present in the chromatin of cells transformed by simian virus 40.", "content": "In vitro transcription of the viral-specific sequences present in the chromatin of cells transformed by simian virus 40. Separated strands of simian virus 40 (SV40) DNA fragments were used in hybridization experiments to study the RNA transcribed by Escherichia coli RNA polymerase from the chromatin of cells transformed by SV40. The template activity of chromatin of the transformed cell line 11A8 (mouse-embryo cells) examined is about 17% that of purified DNA, suggesting that most of the chromatin DNA is repressed by chromosomal proteins. The SV40-specific RNA present in the RNA transcribed in vitro from 11A8 chromatin hybridizes specifically with the minus strand of SV40 DNA. Little or no reaction occurs with the plus strand of viral DNA. The SV40-specific RNA transcribed in vitro from chromatin of transformed cells shares sequences with the RNA produced during the early phase of SV40 lytic infection, and is similar to that present in the 11A8 cell line in vivo. Although the influence of chromosomal proteins on this pattern of transcription was not definitely determined, preliminary evidence indicates that an asymmetric pattern of transcription may also occur when 11A8 DNA is transcribed by E. coli RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357875"}
{"pmid": "4357876", "title": "Bone morphogenesis in implants of insoluble bone gelatin.", "content": "Bone morphogenesis in implants of insoluble bone gelatin. Insoluble bone gelatin with inclusions of insoluble noncollagenous protein produces new bone when implanted in muscle in allogeneic rats. The implanted residue provides the milieu for expression of bone morphogenetic potential of migratory mesenchymal cells. Neutral buffer solutions activate endogenous enzymes that degrade components essential for cell interactions and differentiation of bone. Chloroform-methanol either denatures or extracts constituents responsible for degradation. Insoluble bone gelatin produces new bone after extraction at 2 degrees with neutral salts, 0.5 M EDTA, 0.1 M Tris.HCl, 4 M urea, 0.5 M hydroxylamine, and 10 M KCNS, as well as after limited digestion with pepsin or collagenase, but not after extraction with 5 M guanidine, 7 M urea, water saturated with phenol, or after alkali hydrolysis with 0.1 N NaOH. The specific activity of cell populations interacting with insoluble bone gelatin suggests that a chemical bond between collagen and a noncollagenous protein or part of a protein, cleaved by a neutral proteinase, controls the bone morphogenetic reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357876"}
{"pmid": "4357878", "title": "Cytochrome c: observation of numerous single-carbon sites of the reduced and oxidized species by means of natural-abundance 13C nuclear magnetic resonance spectroscopy.", "content": "Cytochrome c: observation of numerous single-carbon sites of the reduced and oxidized species by means of natural-abundance 13C nuclear magnetic resonance spectroscopy. Proton-decoupled, natural-abundance (13)C nuclear magnetic resonance spectra (obtained at 15.18 MHz by the Fourier transform method) of aqueous ferrocytochrome c, ferricytochrome c, and mixtures of both species were recorded. The 18 nonprotonated aromatic carbons of amino-acid residues and the 16 nonprotonated aromatic carbons of the heme yielded 22 narrow single-carbon resonances and 6 narrow two-carbon resonances in the spectrum of ferrocytochrome c. Only some of these resonances were detected in the spectrum of ferricytochrome c. Fast electron transfer between ferrocytochrome c and ferricytochrome c produced chemical exchange effects in spectra of mixtures of the two species: 16 nonprotonated aromatic carbons yielded narrow exchange-averaged resonances as a consequence of their small natural linewidths in both redox states and the small changes in their chemical shifts (relative to the reciprocal of the lifetime between electron exchange) when going from the reduced to the oxidized species. These peaks were assigned to carbons situated far from the iron atom. Their fast exchange behavior was used to establish a one-to-one correspondence between resonances in spectra of the two redox states. The other 18 nonprotonated aromatic carbons yielded exchange-broadened resonances as a consequence of large chemical-shift differences between the diamagnetic and paramagnetic species, and/or large paramagnetic broadening of the resonances of ferricytochrome c. We assigned these resonances (only one of which was identified in the spectrum of ferricytochrome c alone) to carbons that are near the iron atom: C(zeta) of Tyr 67, C(gamma) of His 18, and the 16 nonprotonated carbons of the porphyrin ring. Tentative specific assignments for C(zeta) of Tyr 67 (in the spectra of both redox forms) and for C(zeta) of His 18 (in the spectrum of ferrocytochrome c) are also presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357878"}
{"pmid": "4357877", "title": "Regulation of nucleoside cyclic 3':5'-monophosphate phosphodiesterase activity from rat brain by a modulator and Ca2+.", "content": "Regulation of nucleoside cyclic 3':5'-monophosphate phosphodiesterase activity from rat brain by a modulator and Ca2+. Gel filtration of the 40,000 rpm supernatant fraction of a homogenate of rat cerebral cortex on a Sepharose 6B column yielded two fractions: fraction II with the \"Ca(2+) plus Mg(2+)-dependent\" phosphodiesterase activity and fraction III containing its modulator. The activity of fraction II was stimulated by micromolar concentrations of Ca(2+) and the modulator when present together; the modulator stimulated the activity of fraction II only when the Ca(2+) concentration was above a threshold value (about 2 muM with 0.4-1 muM substrate), and the stimulatory effect of Ca(2+) was dependent upon the presence of the modulator. A possibility is discussed that the modulator may reversibly bind to the enzyme, which by itself is inactive, to form an active enzyme-modulator complex and that Ca(2+) stimulates the activity of phosphodiesterase by shifting the equilibrium between these three species towards the formation of the active enzyme-modulator complex. Although fraction II hydrolyzed both cyclic AMP and cyclic GMP, hydrolysis of the latter was more significantly influenced by Ca(2+) and the modulator than that of the former, and the \"Ca(2+) plus Mg(2+)-dependent\" phosphodiesterase is likely to be a cyclic GMP enzyme. This conclusion is based on the following evidence: (a) Ca(2+) stimulated hydrolysis of cyclic GMP by fraction II more than that of cyclic AMP. (b) In the presence of Ca(2+) and the modulator, fraction II hydrolyzed cyclic GMP about 8 times faster than cyclic AMP when incubated with 0.4 muM substrate. (c) Half-maximal stimulation of hydrolysis of cyclic GMP was attained at a lower concentration of Ca(2+) (4 muM) than that of cAMP (8 muM). (d) Increase in the concentration of Ca(2+) from 0.06 muM to 12 muM in the presence of the modulator caused a decrease in the K(m) value of cyclic GMP hydrolysis by fraction II from 20 muM to 2 muM accompanied by 4-fold increase in the V(max) value. Under similar conditions, there was only a slight decrease in the K(m) value of cylic AMP hydrolysis (90 muM --> 50 muM), although the V(max) value increased 7-fold. The anomalous shape of the kinetic plot of cyclic GMP hydrolysis became linear when the Ca(2+) concentration was increased in the presence of the modulator. The modulator seems to be a protein, but it is heat stable. It is probably identical to the protein activator of phosphodiesterase first described by Cheung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357877"}
{"pmid": "4357880", "title": "In vitro synthesis of RNA that contains polyadenylate by virion-associated RNA polymerase of vesicular stomatitis virus.", "content": "In vitro synthesis of RNA that contains polyadenylate by virion-associated RNA polymerase of vesicular stomatitis virus. The RNA synthesized in vitro by the virion-associated RNA-instructed RNA polymerase of purified vesicular stomatitis virus contains polyadenylate sequences. These have been demonstrated by their partial resistance to pancreatic and T(1) ribonucleases and their capacity to bind to poly(U) filters and oligo(dT)-cellulose. The polyadenylate sequences range in apparent size from 50 to 200 bases, similar to the size of the poly(A) in mRNA from vesicular stomatitis virus-infected cells. Possible mechanisms of polyadenylylation of the in vitro RNA product are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357880"}
{"pmid": "4357879", "title": "Ribonucleic acid components of murine sarcoma and leukemia viruses.", "content": "Ribonucleic acid components of murine sarcoma and leukemia viruses. Defective Kirsten murine sarcoma virus was present as leukemia virus pseudotype [Ki-MSV(MLV)] in a 10- to 100-fold excess over its helper, Kirsten murine leukemia virus (Ki-MLV), when the two viruses were propagated in an NRK rat cell line. The s(omega,20) of the fastsedimenting RNA complex of Ki-MLV and of Ki-MSV-(MLV) was 62 S and 55 S, respectively. Gel electrophoresis in buffered aqueous or formamide solution of the dissociated 62S RNA complex of Ki-MLV showed a single major peak of molecular weight about 2.5 x 10(6). Dissociated 55S RNA of Ki-MSV(MLV) was resolved into a major component with a higher electrophoretic mobility than that of Ki-MLV RNA and molecular weight about 2.3 x 10(6). Occasionally, a minor component with the same electrophoretic mobility as Ki-MLV RNA was observed in Ki-MSV(MLV) RNA; it is thought to be the RNA of Ki-MLV present as helper virus in our stocks of Ki-MSV(MLV). The RNA of an endogenous rat C-type RNA virus was electrophoretically different from both Ki-MLV RNA and Ki-MSV(MLV) RNAs. Oligonucleotide fingerprinting of the RNAs digested with RNase T1 indicated that the RNAs of Ki-MSV(MLV) and Ki-MLV are different. However, the extent of the difference between the two RNAs could not be estimated by this method. The heat-dissociated 50-70S RNAs of two other defective murine sarcoma-leukemia viruses; Harvey-MSV(MLV) and Moloney-MSV(MLV) and of defective spleen-focus-forming Friend virus were resolved electrophoretically into two components. The larger components had the same electrophoretic mobility as the RNA of Ki-MLV or Moloney MLV. The smaller were not present in leukemia virus. It is suggested that the small RNA components of the two murine viruses and of Friend virus represent specific genetic information of these replication-defective transforming viruses. Possible relationships between the RNAs of murine leukemia viruses and replication-defective murine sarcoma and Friend viruses are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357879"}
{"pmid": "4357881", "title": "Electron transport-linked compared with proton-induced ATP generation in Thiobacillus novellus.", "content": "Electron transport-linked compared with proton-induced ATP generation in Thiobacillus novellus. The apparently soluble electron-transport system, that does not sediment when centrifuged at 144,000 x g or 300,000 x g for 3 hr, catalyzes oxidative phosphorylation with an efficiency comparable to that of an intact mitochondrial system. While the proton-induced phosphorylation occurs in whole cells, crude cell-free extracts, and supernatants from low-speed centrifugation, it does not occur in either the 144,000 or 300,000 x g supernatant fractions. The data show that oxidative energy can be conserved as ATP under conditions that are incompatible with the basic postulate of the chemiosmotic hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357881"}
{"pmid": "4357882", "title": "Role of cyclic 3':5'-adenosine monophosphate in the early transport changes induced by serum and insulin in quiescent fibroblasts.", "content": "Role of cyclic 3':5'-adenosine monophosphate in the early transport changes induced by serum and insulin in quiescent fibroblasts. Serum or insulin added to quiescent mouse-embryo fibroblasts produced rapid increases in the rate of transport of uridine and phosphate and a decrease of the intracellular concentration of cyclic AMP. Incubation of the cells with prostaglandin E(1), theophylline, or both prevented the increase in uridine transport produced by serum or insulin. Prostaglandin E(1) was more effective than prostaglandins E(2) and B(1). Kinetic experiments showed that the addition of prostaglandin E(1) and theophylline causes the uridine transport rate to return to the basal level within 5 min; the rate rose rapidly after their removal. Similar effects were obtained when insulin was used instead of serum. Associated with these transport changes were significant variations in the levels of cyclic AMP. An inverse correlation between the changes in uridine transport and those in cyclic AMP concentration was shown under various experimental conditions. In contrast to the effects observed with uridine transport, phosphate uptake was only slightly affected by changes in the endogenous level of cyclic AMP. We propose that at least two different sorts of membrane changes are rapidly initiated by serum, one under cyclic AMP control and the other not related to this nucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357882"}
{"pmid": "4357883", "title": "Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7.", "content": "Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7. Hybrid cell clones between mouse cells deficient in thymidine kinase (EC 2.7.1.21) and two different human cell lines transformed by simian virus 40 (SV40) and deficient in hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) were examined for SV40 tumor (T) antigen(s). Concordant segregation of the gene(s) for SV40 T antigen and human chromosome C-7 was observed in these hybrids. The human chromosome C-7 which contains the gene(s) for SV40 T antigen is preferentially retained by the majority of the hybrid clones tested. When hybrid clones positive and negative for SV40 T antigen, derived from the fusion of SV40-transformed Lesch-Nyhan fibroblasts with mouse cells, were fused with CV-1 permissive cells, SV40-specific V antigen was observed only in the cultures derived from fusion of the hybrid clones positive for T antigen. This result indicates a linkage relationship between human chromosome C-7, SV40 T-antigen gene(s), and SV40 genome(s) integrated in the human transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357883"}
{"pmid": "4357885", "title": "Changes in membrane structure associated with cell contact.", "content": "Changes in membrane structure associated with cell contact. Ultrastructural analysis of 3T3 fibroblasts by freeze-cleavage has demonstrated significant changes in cell-membrane structure associated with cell-to-cell contact and malignant transformation. These changes consist of a rearrangement and redistribution of intramembranous particles on the membrane fracture faces exposed by freeze-cleavage. The results show that noncontacted 3T3 cells in low density contain randomly distributed intramembranous particles. With the development of cell-to-cell contacts during the logarithmic phase of growth however, a pronounced aggregation of intramembranous particles is seen. A direct correlation between the degree of cell contact and the percentage of cells showing intramembranous-particle aggregation has been established. By contrast, transformed SV3T3 and SP3T3 cells show no evidence of intramembranous-particle aggregation even at cell densities where cell-to-cell contact is extensive. In view of recent reports that intramembranous particles represent foci of interaction between certain intrinsic membrane proteins and lipids, we propose that cell-to-cell contact of nontransformed 3T3 cells may initiate a change in the distribution of intrinsic membrane proteins associated with intramembranous particles and that these changes may influence control of cell proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357885"}
{"pmid": "4357886", "title": "Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting.", "content": "Changes in rabbit-liver lysosomes and fructose 1,6-bisphosphatase induced by cold and fasting. Exposure of rabbits to cold or fasting results in marked increases in the number and size of liver lysosomes, associated with increases in the total and \"free\" proteolytic activity. Changes in lysosomal morphology also indicate increased activity and fragility. These effects of cold and fasting are correlated with decreases in the levels of liver fructose bisphosphatase (EC 3.1.3.11) activity and changes in the molecular properties of the purified enzyme, including the loss of a small peptide containing the only tryptophan residue in the peptide chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357886"}
{"pmid": "4357884", "title": "Infectious DNA from herpes simplex virus: infectivity of double-stranded and single-stranded molecules.", "content": "Infectious DNA from herpes simplex virus: infectivity of double-stranded and single-stranded molecules. The infectious units in native and alkalidenatured preparations of DNA of herpes simplex virus were characterized with respect to their sensitivity to Neurospora crassa endonuclease, their sedimentation properties in high-salt, neutral sucrose gradients, and their sensitivity to hydrodynamic shearing forces. Infectious molecules in native preparations were resistant to N. crassa endonuclease, sedimented at 56 S, and were highly sensitive to shearing forces. After alkaline denaturation, infectious molecules became sensitive to the N. crassa enzyme, sedimented at 200 S, and were relatively resistant to shear. We conclude that both intact duplex molecules ([unk]100 x 10(6) daltons) and intact single strands ([unk]50 x 10(6) daltons) are capable of initiating productive infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357884"}
{"pmid": "4357887", "title": "In vivo inhibition of growth of two hormone-dependent mammary tumors by dibutyryl cyclic AMP.", "content": "In vivo inhibition of growth of two hormone-dependent mammary tumors by dibutyryl cyclic AMP. Growth of hormone-dependent rat mammary tumors was arrested in vivo by N(6),O(2)'-dibutyryl cyclic adenosine 3',5'-monophosphate. Estrogen concentration did not change, but acid ribonuclease activity and synthesis increased during treatment with the dibutyryl cyclic nucleotide, as was shown during tumor regression due to hormonal deprivation. Growth arrest, thus, appears to derive from enhanced tissue catabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357887"}
{"pmid": "4357889", "title": "Water-soluble contrast media and adhesive arachnoiditis. I. Reinvestigation of nonoperated cases.", "content": "Water-soluble contrast media and adhesive arachnoiditis. I. Reinvestigation of nonoperated cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357889"}
{"pmid": "4357890", "title": "Late sequelae following lumbar myelography with water-soluble contrast media.", "content": "Late sequelae following lumbar myelography with water-soluble contrast media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357890"}
{"pmid": "4357891", "title": "Streptozotocin diabetes--further studies on the mechanism of depression of nicotinamide adenine dinucleotide concentrations in mouse pancreatic islets and liver.", "content": "Streptozotocin diabetes--further studies on the mechanism of depression of nicotinamide adenine dinucleotide concentrations in mouse pancreatic islets and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357891"}
{"pmid": "4357892", "title": "Effects of some isoquinoline compounds and certain derivatives on brain phosphodiesterase activity.", "content": "Effects of some isoquinoline compounds and certain derivatives on brain phosphodiesterase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357892"}
{"pmid": "4357893", "title": "Biliary excretion of nicotinamide riboside. A possible role in the regulation of hepatic pyridine nucleotide dynamics.", "content": "Biliary excretion of nicotinamide riboside. A possible role in the regulation of hepatic pyridine nucleotide dynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357893"}
{"pmid": "4357895", "title": "Neural activity in the dorsal hippocampus during paradoxical sleep, slow wave sleep and waking.", "content": "Neural activity in the dorsal hippocampus during paradoxical sleep, slow wave sleep and waking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357895"}
{"pmid": "4357894", "title": "Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. IV. Stimulation of the enzyme activity in established cell lines derived from rat or mouse hepatoma and from normal rat liver.", "content": "Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. IV. Stimulation of the enzyme activity in established cell lines derived from rat or mouse hepatoma and from normal rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357894"}
{"pmid": "4357897", "title": "Glial uptake of taurine in the rabbit retina.", "content": "Glial uptake of taurine in the rabbit retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357897"}
{"pmid": "4357896", "title": "Evidence against cyclic adenosine 3',5'-monophosphate (AMP) mediation of noradrenaline depression of cerebral cortical neurones.", "content": "Evidence against cyclic adenosine 3',5'-monophosphate (AMP) mediation of noradrenaline depression of cerebral cortical neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357896"}
{"pmid": "4357898", "title": "Talc injury: changes in glucosamine and leucine incorporation into liver and plasma proteins.", "content": "Talc injury: changes in glucosamine and leucine incorporation into liver and plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357898"}
{"pmid": "4357899", "title": "Familial hyperlipoproteinemia and thyroid dysfunction of beagles.", "content": "Familial hyperlipoproteinemia and thyroid dysfunction of beagles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357899"}
{"pmid": "4357901", "title": "Influences on the structural stability of collagen in relation to ageing.", "content": "Influences on the structural stability of collagen in relation to ageing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357901"}
{"pmid": "4357903", "title": "Increased plasma renin substrate concentration in human malignant hypertension.", "content": "Increased plasma renin substrate concentration in human malignant hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357903"}
{"pmid": "4357902", "title": "Effect of 25-hydroxycholecalciferol (25-HCC) on intestinal absorption of 47Ca in four cases of iatrogenic Cushing's syndrome.", "content": "Effect of 25-hydroxycholecalciferol (25-HCC) on intestinal absorption of 47Ca in four cases of iatrogenic Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357902"}
{"pmid": "4357904", "title": "Serum lipids, dietary intakes, and physical exercise in medical students.", "content": "Serum lipids, dietary intakes, and physical exercise in medical students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357904"}
{"pmid": "4357906", "title": "Depth-electroencephalograms of chickens in wakefulness and sleep.", "content": "Depth-electroencephalograms of chickens in wakefulness and sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357906"}
{"pmid": "4357908", "title": "Letter: The stability of Clostridium perfringans type D epsilon toxin in intestinal contents in vitro.", "content": "Letter: The stability of Clostridium perfringans type D epsilon toxin in intestinal contents in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357908"}
{"pmid": "4357909", "title": "Terminal dentistry and the management of the atrophied mandible.", "content": "Terminal dentistry and the management of the atrophied mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357909"}
{"pmid": "4357910", "title": "A genetic study of syndactyly in Utah.", "content": "A genetic study of syndactyly in Utah.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357910"}
{"pmid": "4357913", "title": "Alkaline phosphatase levels in canine mammary neoplasia.", "content": "Alkaline phosphatase levels in canine mammary neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357913"}
{"pmid": "4357922", "title": "Chemical oncogenesis in culture.", "content": "Chemical oncogenesis in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357922"}
{"pmid": "4357923", "title": "Isozymes and cancer.", "content": "Isozymes and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357923"}
{"pmid": "4357929", "title": "Effect of 5-iodo-2-deoxyuridine, cycloheximide and rivanol on the multiplication of vaccinia and fowlpox viruses in chick embryo fibroblast culture.", "content": "Effect of 5-iodo-2-deoxyuridine, cycloheximide and rivanol on the multiplication of vaccinia and fowlpox viruses in chick embryo fibroblast culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357929"}
{"pmid": "4357930", "title": "Bordetella pertussis infection in Chandigarh.", "content": "Bordetella pertussis infection in Chandigarh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357930"}
{"pmid": "4357931", "title": "Variants of vibrio cholerae in Delhi.", "content": "Variants of vibrio cholerae in Delhi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357931"}
{"pmid": "4357932", "title": "Vitamin D and rickets.", "content": "Vitamin D and rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357932"}
{"pmid": "4357934", "title": "Isolation of Clostridium absonum and its cultural and biochemical properties.", "content": "Isolation of Clostridium absonum and its cultural and biochemical properties. A new procedure for isolation of Clostridium absonum was devised. Sixtyseven strains of C. absonum were isolated from 135 soil samples, but no strain of C. absonum could be found from human fecal samples. The lecithinase, hemolysin, and lethal toxin in the culture filtrates of this species exhibited low avidity for C. perfringens type A antitoxin. The three activities were inseparable by the present method of purification. A reinvestigation of biochemical properties revealed that incomplete suppression of lecithinase reaction by C. perfringens type A antitoxin and no fermentation of raffinose, melibiose, and starch are useful criteria to differentiate C. absonum from C. perfringens, and that positive, although weak, gelatin liquefaction and fermentation of trehalose are useful to differentiate it from C. paraperfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357934"}
{"pmid": "4357933", "title": "Inhibitory and restorative effects of adenine nucleotides on rickettsial adsorption and hemolysis.", "content": "Inhibitory and restorative effects of adenine nucleotides on rickettsial adsorption and hemolysis. The adenine nucleotides, adenosine diphosphate, adenosine triphosphate, (ATP), and the methylene-bridge analogues are inhibitors of rickettsial adsorption to and the hemolysis of sheep erythrocytes. Other nucleotides, adenosine monophosphate, cyclic adenosine monophosphate, cytosine triphosphate, and guanosine triphosphate, are without effect. Adsorption and hemolysis require the generation of energy by the rickettsiae which is usually derived from glutamate. When the generation of energy from the metabolism of glutamate is inhibited by arsenite or cyanide, the addition of ATP can supply the energy to restore hemolysis. However, in the presence of the uncouplers, ATP can not restore hemolysis. Even when functioning in a restorative role, ATP still has its inhibitory properties. These results suggest that a high-energy intermediate (X approximately I), rather than ATP itself, is the energy source. The interactions of inhibitory nucleotides suggest that these compounds share a common transport system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357933"}
{"pmid": "4357935", "title": "N-terminal aspartate, glycine and serine in poliovirus capsid protein.", "content": "N-terminal aspartate, glycine and serine in poliovirus capsid protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357935"}
{"pmid": "4357936", "title": "The synthesis and substructure of herpesvirus DNA: the distribution of alkali-labile single strand interruptions in HSV-1 DNA.", "content": "The synthesis and substructure of herpesvirus DNA: the distribution of alkali-labile single strand interruptions in HSV-1 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357936"}
{"pmid": "4357937", "title": "Fusion of a Rous sarcoma virus transformed human cell line, KC, by RD-114 virus.", "content": "Fusion of a Rous sarcoma virus transformed human cell line, KC, by RD-114 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357937"}
{"pmid": "4357938", "title": "Studies on the histamine sensitisation produced in mice by Corynebacterium parvum.", "content": "Studies on the histamine sensitisation produced in mice by Corynebacterium parvum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357938"}
{"pmid": "4357940", "title": "Activation of descending control of the spinocervical tract by impulses ascending the dorsal columns and relaying through the dorsal column nuclei.", "content": "Activation of descending control of the spinocervical tract by impulses ascending the dorsal columns and relaying through the dorsal column nuclei. 1. Micro-electrode recordings were made from axons of the spinocervical tract in unanaesthetized decerebrate cats.2. Orthodromic activation of the dorsal columns and dorsal column nuclei was used to condition responses evoked in spinocervical tract neurones from cutaneous nerves. Such conditioning produced inhibition of transmission through the tract. The inhibition had a time course of 200 msec or more with maximal action at 30-70 msec and was most effective against polysynaptic responses.3. After removal of the cerebellum or section of the cerebellar peduncles the degree of inhibition was reduced but inhibition could still be evoked by activation of the dorsal columns and dorsal column nuclei.4. Transection of the brain stem just rostral to the dorsal column nuclei removed the inhibitory effects although segmental inhibition was not affected.5. It is concluded that impulses ascending the dorsal columns and relaying through the dorsal column nuclei can lead to activation of descending control of the spinocervical tract. Parts of the pathways involved include the cerebellum and the brain stem. It is unlikely that the cells in the dorsal column nuclei which have descending axons are concerned with the control of transmission through the spinocervical tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357940"}
{"pmid": "4357939", "title": "Some effects of preganglionic nerve stimulation on synaptic vesicle populations in the rat superior cervical ganglion.", "content": "Some effects of preganglionic nerve stimulation on synaptic vesicle populations in the rat superior cervical ganglion. 1. The ;local vesicle population', namely the population of synaptic vesicles lying within a zone 0.25 mum wide adjacent to the presynaptic membrane and expressed as ;vesicles mum(-2)' has been estimated in rat superior cervical ganglia maintained in vitro for 1 h. Ganglia were either unstimulated or stimulated tetanically during the last few minutes of the in vitro period.2. Individual local vesicle populations at synapses in groups of ganglia which had received the same treatment showed an approximately normal frequency distribution.3. The technique of stimulation did not permit fixation during tetanus, but the mean local vesicle population in ganglia fixed a few seconds after 10 Hz tetani of up to 10 min duration were significantly (P < 0.001) higher than the unstimulated control value of 124.0 +/- S.E. 3.2. Ganglia fixed a few seconds after 3 min tetani at 10 Hz had a mean local vesicle population of 155.7 +/- S.E. 5.7, rising slightly but not significantly to 165.0 +/- S.E. 4.3 at 1 min and 163.1 +/- S.E. 5.2 at 2 min after tetanus. Thereafter the mean local vesicle population fell slowly, reaching control level between 10 and 20 min after tetanus.4. In terms of the vesicle hypothesis, the observations suggest that post-tetanic potentiation might arise from a closer clustering of vesicles about release areas resulting in an increase in fractional release. It is suggested that stimulation increased the local vesicle population by promoting vesicle mobilization rather than by altering the size or shape of the presynaptic terminals. The ;mobilizing agent' might be intracellular Ca(2+).5. The results appear to be consistent with those of other workers where experimental conditions and the region in which vesicles were counted were comparable.6. Alternative interpretations for the findings, not involving the vesicle hypothesis, are considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357939"}
{"pmid": "4357946", "title": "Negative inotropic effect of cyclic AMP on the isolated canine heart muscle.", "content": "Negative inotropic effect of cyclic AMP on the isolated canine heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357946"}
{"pmid": "4357945", "title": "Thymus adenylate cyclase activity during murine leukemogenesis.", "content": "Thymus adenylate cyclase activity during murine leukemogenesis. Activity of thymus adenylate cyclase was more than three times higher in leukemic AKR mice than in nonleukemic AKR mice and CBA mice. Preleukemic AKR mice that had no evidence of leukemia but were expected to soon develop the disease exhibited similarly elevated activities of thymus adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357945"}
{"pmid": "4357947", "title": "The cricopharyngeus muscle. An electrophysiological and neuropharmacological study.", "content": "The cricopharyngeus muscle. An electrophysiological and neuropharmacological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357947"}
{"pmid": "4357948", "title": "Unit activity of ganglionic and medullary second order neurones in the eel lateral line system.", "content": "Unit activity of ganglionic and medullary second order neurones in the eel lateral line system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357948"}
{"pmid": "4357953", "title": "Effect of feeding protected lipid on the uptake of precursors of milk fat by the bovine mammary gland.", "content": "Effect of feeding protected lipid on the uptake of precursors of milk fat by the bovine mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357953"}
{"pmid": "4357954", "title": "Tumor producing capacity of temperature sensitive mutants of avian sarcoma viruses in chicks.", "content": "Tumor producing capacity of temperature sensitive mutants of avian sarcoma viruses in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357954"}
{"pmid": "4357955", "title": "Studies by electron paramagnetic resonance on the catalytic mechanism of nitrogenase of Klebsiella pneumoniae.", "content": "Studies by electron paramagnetic resonance on the catalytic mechanism of nitrogenase of Klebsiella pneumoniae. The properties and catalytic reactions of the enzyme nitrogenase purified from Klebsiella pneumoniae were studied by electron-paramagnetic-resonance (e.p.r.) spectroscopy at temperatures down to 8 degrees K. The two protein fractions, Kp1 (the iron-molybdenum protein) and Kp2 (the iron protein), were examined alone and in steady-state mixtures and also in pre-steady-state experiments, by using the rapid-freezing method. Kp1 protein in dithionite solution shows a rhombic type of spectrum with g(1) 4.32, g(2) 3.63, g(3) 2.009 at pH6.8 (0 degrees C). Small changes in the spectrum produced by protons (pK=8.7 at 0 degrees C) or by acetylene indicate binding of these oxidizing substrates to this protein fraction. Kp2 protein shows a rhombic spectrum with g(1) 2.053, g(2) 1.942, g(3) 1.865, which integrates to about 0.45 electron/molecule. Binding of ATP, with a dissociation constant of 4x10(-4)m, changes the spectrum to an axial form with g( parallel) 2.036, g( perpendicular) 1.929, thus indicating a conformation change of Kp2 protein. The Kp2 protein spectrum disappears reversibly on cautious oxidation. The signals of both proteins are diminished in their steady-state mixtures, obtained in the presence of ATP and dithionite (with an ATP-generating system and Mg(2+) ions) and with protons, N(2) or acetylene as oxidizing substrate. At the same time as dithionite is consumed in such reactions, the Kp1 protein signal is gradually restored and the Kp2 protein signal diminishes to zero. In rapid-freezing experiments the signals from the two proteins decreased at indistinguishable rates (t((1/2)) about 10ms), then they remained constant. Results are interpreted in terms of a scheme in which reducing equivalents pass from dithionite to Kp2 protein, then, in an ATP-dependent reaction to Kp1 protein, this being finally reoxidized by N(2) or another oxidizing substrate. In this scheme Kp1 protein cycles between its signal-giving state and a very highly reduced signal-free state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357955"}
{"pmid": "4357957", "title": "Electrical changes in the membrane in junctional transmission.", "content": "Electrical changes in the membrane in junctional transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357957"}
{"pmid": "4357958", "title": "Mental health: systems and non-systems.", "content": "Mental health: systems and non-systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357958"}
{"pmid": "4357956", "title": "Superoxide dismutase: a contaminant of bovine catalase.", "content": "Superoxide dismutase: a contaminant of bovine catalase. Some commercial samples of bovine catalase contain superoxide dismutase activity. Therefore the inhibition of a reaction on the addition of a catalase preparation need not necessarily mean that H(2)O(2) is responsible for the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357956"}
{"pmid": "4357960", "title": "The action of bombesin on the kidney of the anaesthetized dog.", "content": "The action of bombesin on the kidney of the anaesthetized dog. 1. In the anaesthetized dog bombesin had a potent antidiuretic effect, and sometimes arrested urine flow completely. Threshold doses, by i.v. infusion, were of the order of 0.5-1 (ng/kg)/minute. Antidiuresis was the result of a reduction in glomerular filtration rate provoked by a fall in intraglomerular hydrostatic pressure. This, in its turn, was due to afferent vasoconstriction.2. The spasmogenic effect of bombesin on the smooth muscle of the afferent arterioles was directly demonstrated by the radioactive microspheres technique and indirectly by the (85)Kr washout method and by [(3)H]-p-aminohippurate clearance. The vascular compartment most sensitive to bombesin was that of the outer cortical zone, especially in its external half.3. Filtration fraction decreased under the influence of bombesin, indicating that the effect of the polypeptide on postglomerular arterioles was, if present, only of minor importance.4. At high infusion rates (above 6 (ng/kg)/min), bombesin produced a decrease in [(3)H]-p-aminohippurate extraction. The effect of the polypeptide on fractional distal delivery of sodium varied with the dose: at moderate infusion rates it decreased, at high infusion rates it increased. The total glucose appearing in urine following a glucose load was sharply reduced by bombesin. However, the glomerular filtration rate/maximum tubular glucose transport ratio did not show any appreciable change.5. Afferent vasoconstriction produced by bombesin was accompanied by an intense activation of the renin-angiotensin system, as shown by a conspicuous increase in renin secretion, followed by increases in renin activity and angiotensin II concentration in arterial blood. When bombesin was infused into one renal artery only the infused kidney showed afferent vasoconstriction and increased renin secretion. The time-course of renin secretion produced by bombesin depended upon the rate of infusion of the polypeptide. At low rates an increased renin secretion was observed throughout the infusion period, at high rates two peaks of renin secretion could be seen, one at the beginning of the infusion, the other soon after the infusion had finished.6. The mechanism of action of bombesin is discussed and the interest of the polypeptide as a possible hormonal regulator of the circulation and function of the kidney is pointed out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357960"}
{"pmid": "4357959", "title": "On the pharmacology of ascending, decending and recurrent postsynaptic inhibition of the cuneo-thalamic relay cells in the cat.", "content": "On the pharmacology of ascending, decending and recurrent postsynaptic inhibition of the cuneo-thalamic relay cells in the cat. 1. In cats decerebrated or anaesthetized with pentobarbitone, cells of the middle third of the cuneate nucleus that were excited by tactile stimulation of the ipsilateral forelimb (responding to displacement of hairs, skin or joints) and inhibited by electrical stimulation of the contralateral pyramid, were invariably inhibited by electrical stimulation of the ipsilateral forepaw and the contralateral forelimb nerves.2. In 50% of the cats, the cells were more fully identified by placing electrodes stereotaxically in the contralateral medial lemniscus. Recurrent inhibition was always a concomitant of the antidromic action potential.3. The intensity and the duration of inhibition evoked by all of these pathways was totally resistant to iontophoretic and intravenous strychnine in doses at least 5 times that required to block completely the response of the same cells to iontophoretic glycine and was extremely sensitive to either iontophoretic bicuculline or picrotoxin.4. Although the inhibition was invariably sensitive to intravenous picrotoxin, no significant change occurred in the duration or intensity of the inhibition when bicuculline was administered intravenously (5 or 6 times) as repeated doses of 0.2 mg/kg.5. Postsynaptic inhibition in the cuneate may be mediated by gamma-aminobutyric acid released from the nerve terminals of a common pool of interneurones shared by ascending, descending and recurrent pathways. Since the receptors involved in this pathway are resistant to intravenous bicuculline, they may well be distinct from those responsible for changes in the primary afferent terminal excitability, usually believed to be associated with presynaptic inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357959"}
{"pmid": "4357961", "title": "Fate of angiotension I in the total Bufo melanostictus.", "content": "Fate of angiotension I in the total Bufo melanostictus. 1. The effects of angiotensin I and II on the blood pressure of pithed toads and the disappearance of angiotensin I and II in the perfused organs of the toad were studied.2. Angiotensin I was relatively inactive on the blood pressure of pithed toads; it exhibited less than 3% of the pressor activity of angiotensin II.3. Angiotensin I was not converted to angiotensin II during passage through the lungs. There was also no evidence of net conversion during passage through the kidney and hind quarters.4. During passage through the lungs, 33-50% of angiotensin I was removed and 25-50% was removed during passage through the hind quarters. No loss of activity was detected when angiotensin II passed through the kidneys.5. Angiotensin II passed through the lungs and kidneys without loss but 25-50% disappeared during passage through the hind quarters.6. The relatively low pressor activity of angiotensin I together with its lack of conversion to angiotensin II in isolated perfused organs suggest that the converting enzyme is absent in the toad, Bufo melanostictus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357961"}
{"pmid": "4357962", "title": "Effect of anti-inflammatory drugs on the binding of calcium to cellular membranes in various human and guinea-pig tissues.", "content": "Effect of anti-inflammatory drugs on the binding of calcium to cellular membranes in various human and guinea-pig tissues. 1. Cellular membranes were obtained by centrifugation of homogenates of various human and guinea-pig tissues. These membranes took up added calcium (Ca) when incubated at 25 degrees C for 10 min in histidine buffer at pH 7.4. The uptake of Ca was increased by the presence of adenosine triphosphate (ATP).2. Evidence is presented that the membrane fragments which took up Ca under these conditions were derived from the endoplasmic reticulum.3. The ATP-dependent uptake of Ca by membranes derived from guinea-pig aortic or gastric smooth muscle or from human umbilical arterial muscle was inhibited by indomethacin in a concentration-dependent manner.4. The ATP-dependent uptake of Ca by membranes derived from heart, brain, skeletal muscle or liver of the guinea-pig was not inhibited by indomethacin.5. Endothelial cells were obtained from the lining of the human umbilical vein. Cellular membranes were prepared from the endothelial cells by homogenization and centrifugation. The endothelial membranes took up added Ca in the presence of added ATP and this uptake was inhibited by indomethacin and also by members of a group of pharmacologically-related drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357962"}
{"pmid": "4357963", "title": "The relation of adenyl cyclase to the activity of other ATP utilizing enzymes and phosphodiesterase in preparations of rat brain; mechanism of stimulation of cyclic AMP accumulation by NaF.", "content": "The relation of adenyl cyclase to the activity of other ATP utilizing enzymes and phosphodiesterase in preparations of rat brain; mechanism of stimulation of cyclic AMP accumulation by NaF. 1. A method for measuring the rate of production of (14)C-labelled adenine nucleotides, including cyclic adenosine 3',5'monophosphate (cyclic AMP), from [(14)C]-adenosinetriphosphate (ATP) was developed and used to study the effects of ATP, adenosine diphosphate (ADP) and adenosine 5'-monophosphate (AMP) on the rate of accumulation of cyclic AMP in cell-free preparations of adenyl cyclase from rat brain.2. The mechanism by which NaF increases cyclic AMP accumulation was studied by comparing its effect on adenine nucleotide metabolism with that of an ATP regenerating system.3. ADP and ATP are potent inhibitors of phosphodiesterase (PDE) and it is the sum of the concentrations of these two nucleotides which controlled the rate of destruction of cyclic AMP. The effect of these nucleotides was significant even in the presence of 6.7 mM theophylline; theophylline itself inhibited PDE only 50-60%.4. Fluoride ion had no direct effect on PDE but it inhibited the rate of hydrolysis of ADP and ATP and thus indirectly inhibited PDE. The effect of fluoride ion on cyclic AMP accumulation can be explained, at least in part, by this indirect inhibition of PDE.5. Studies on a more purified preparation of adenyl cyclase clearly demonstrated a direct action of NaF on adenyl cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357963"}
{"pmid": "4357964", "title": "Effect of a sulphated glycopeptide on rat gastric acid secretion stimulated by histamine, bethanechol, pentagastrin and dibutyryl cyclic AMP.", "content": "Effect of a sulphated glycopeptide on rat gastric acid secretion stimulated by histamine, bethanechol, pentagastrin and dibutyryl cyclic AMP. The antisecretory activity of a semisynthetic sulphated glycopeptide (GLPS) was studied in rats in which the secretion rates of gastric acid were detennined on the perfused stomach preparation. GLPS at 1 mg/kg i.v. reduced the hypersecretory effect of dibutyryl cyclic AMP, histamine, pentagastrin, bethanechol but not of theophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357964"}
{"pmid": "4357965", "title": "The action of two inhibitors of glutamic acid uptake upon amino acid-induced and synaptic excitations of thalamic neurones.", "content": "The action of two inhibitors of glutamic acid uptake upon amino acid-induced and synaptic excitations of thalamic neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357965"}
{"pmid": "4357966", "title": "Modifications of the firing rate of bulbar reticular units (nucleus gigantocellularis) after intra-arterial injection of bradykinin into the limbs.", "content": "Modifications of the firing rate of bulbar reticular units (nucleus gigantocellularis) after intra-arterial injection of bradykinin into the limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357966"}
{"pmid": "4357968", "title": "Electrophysiology of the frontal granular cortex. II. Patterns of spontaneous discharges of impulses of neurons in the cortex through states of sleep and wakefulness in the monkey.", "content": "Electrophysiology of the frontal granular cortex. II. Patterns of spontaneous discharges of impulses of neurons in the cortex through states of sleep and wakefulness in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357968"}
{"pmid": "4357967", "title": "The action of piperidine on cholinoceptive neurons of the snail.", "content": "The action of piperidine on cholinoceptive neurons of the snail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357967"}
{"pmid": "4357969", "title": "Altered distribution of choline acetyltransferase and acetylcholinesterase activities in the developing rat dentate gyrus following entorhinal lesion.", "content": "Altered distribution of choline acetyltransferase and acetylcholinesterase activities in the developing rat dentate gyrus following entorhinal lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357969"}
{"pmid": "4357971", "title": "The efflux of 45CA2+ and (3H)gamma-aminobutyric acid from cate cerebral cortex.", "content": "The efflux of 45CA2+ and (3H)gamma-aminobutyric acid from cate cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357971"}
{"pmid": "4357970", "title": "Effect of psychotropic drugs on phosphodiesterase and cyclic AMP level in rat brain in vivo.", "content": "Effect of psychotropic drugs on phosphodiesterase and cyclic AMP level in rat brain in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357970"}
{"pmid": "4357972", "title": "The neuronal pathway subserving the pupillary light reflex and its facilitation from cerebellar nuclei.", "content": "The neuronal pathway subserving the pupillary light reflex and its facilitation from cerebellar nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357972"}
{"pmid": "4357974", "title": "Burst formation in electrically coupled neurons.", "content": "Burst formation in electrically coupled neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357974"}
{"pmid": "4357973", "title": "Studies on post-tetanic depression of the dorsal root reflex in the forelimb skin nerves of the cat.", "content": "Studies on post-tetanic depression of the dorsal root reflex in the forelimb skin nerves of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357973"}
{"pmid": "4357975", "title": "WHO collaborative studies on enterovirus reference antisera; fourth report.", "content": "WHO collaborative studies on enterovirus reference antisera; fourth report. This paper summarizes the results of the fourth part of a comprehensive programme undertaken by the WHO International Reference Centre for Enteroviruses and other laboratories for the testing of enterovirus equine antisera prepared for long-term use as reference antisera. The studies were designed to appraise the specificity of the immune serum of horses inoculated with prototype enteroviruses (coxsackievirus types A2, 4, 8, 10, 11, 14-16, 18-21, and 24, and echoviruses E21, 27, 30, 31, and 33). Tests for neutralizing antibody were performed against the homologous viruses and against available regional homotypic strains. Heterotypic tests were performed against reoviruses 1-3, adenoviruses 1-31, and the entire series of enteroviruses (with the exception of enterovirus 68). The homologous geometric mean titre of the 5 echovirus antisera ranged from 3 000 to 10 000; the titre of 1 coxsackievirus antiserum (A24) was only about 400, but the titres of the others ranged from 1 500 to 14 000. All corresponding preinoculation sera were negative. Heterotypic antibody of significant titre was found in 4 antisera: E31 serum against E5 virus, CA8 serum against CA3 virus, CA13 serum against CA18 virus, and CA15 serum against CA2 virus. Information on other heterotypic antibody titres (where found) is recorded for guidance in the use of the sera. The results of homotypic tests with viruses isolated by the collaborating laboratories, though limited in number, were satisfactory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357975"}
{"pmid": "4357977", "title": "Differential diagnosis of variola viruses by microfocus assay.", "content": "Differential diagnosis of variola viruses by microfocus assay. Variola virus was identified by means of a method involving the formation of microfoci on microplate cultures of HeLa cells. It was possible to distinguish between variola major and variola minor viruses within 48 h of receipt of the specimens by determining the temperature sensitivity of focus formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357977"}
{"pmid": "4357976", "title": "Poliomyelitis: epidemiology and prophylaxis. 1. A longitudinal epidemiological survey in Kenya.", "content": "Poliomyelitis: epidemiology and prophylaxis. 1. A longitudinal epidemiological survey in Kenya. The results of a long-term survey of poliomyelitis in Kenya are reported. Virus was isolated from patients and a limited number of sera were also tested for antibodies. The purpose of the investigation was to elucidate the epidemiological characteristics of the disease and to determine whether epidemics could be predicted. A 3-year rhythm was found in the circulation of type 1 poliovirus, making possible the prediction and hence, on two occasions, the curbing or prevention of epidemics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357976"}
{"pmid": "4357979", "title": "Leukocytic enzyme differences between the clinical forms of malnutrition.", "content": "Leukocytic enzyme differences between the clinical forms of malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357979"}
{"pmid": "4357982", "title": "Experimental myasthenia gravis, myositis and myocarditis in guinea-pigs immunized with subcellular fractions of calf thymus or calf skeletal muscle in Freund's complete adjuvant.", "content": "Experimental myasthenia gravis, myositis and myocarditis in guinea-pigs immunized with subcellular fractions of calf thymus or calf skeletal muscle in Freund's complete adjuvant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357982"}
{"pmid": "4357983", "title": "Macrophage and lymphocyte co-operation in target cell destruction in vitro.", "content": "Macrophage and lymphocyte co-operation in target cell destruction in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357983"}
{"pmid": "4357985", "title": "Perspectives in molecular radiation biology. The biophysical approach.", "content": "Perspectives in molecular radiation biology. The biophysical approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357985"}
{"pmid": "4357986", "title": "Properties of myeloma immunoglobulin E(Yu). Chemical, fluorescence polarisation and spin-labeled studies.", "content": "Properties of myeloma immunoglobulin E(Yu). Chemical, fluorescence polarisation and spin-labeled studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357986"}
{"pmid": "4357987", "title": "Different sensitivity of ribonucleic and deoxyribonucleic acid viruses to resistance induced in rabbit cells (RK-13) by polyriboinosinic acid-polyribocytidilic acid.", "content": "Different sensitivity of ribonucleic and deoxyribonucleic acid viruses to resistance induced in rabbit cells (RK-13) by polyriboinosinic acid-polyribocytidilic acid. When a continuous line of rabbit kidney cells (RK-13) was exposed to polyriboinosinic acid polyribocytidilic acid [poly(rI).poly(rC)], the cells became resistant to the replication of a ribonucleic acid (RNA) virus, vesicular stomatitis (VSV), but remained susceptible to the replication of two deoxyribonucleic acid (DNA) viruses, pseudorabies and vaccinia. These differences were identical to previous findings with RK-13 cells pretreated with exogenous rabbit interferon. Confirmation is thereby provided that RK-13 cells are deficient in the synthesis of resistance factors active against the DNA viruses tested and that there are separate resistance factors for RNA and DNA viruses in RK-13 cells. The resistance against VSV which developed in RK-13 cells exposed to poly(rI).poly(rC) could be significantly reversed by prior infection with infective vaccinia virus but not by vaccinia inactivated by ultraviolet irradiation or heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357987"}
{"pmid": "4357988", "title": "Induction of interferon in L cells by reoviruses.", "content": "Induction of interferon in L cells by reoviruses. L cell cultures challenged with reoviruses types 1 and 3 produced little to no detectable interferon under conditions which permitted virus replication and under conditions which prevented replication of a temperature-sensitive mutant strain of reovirus type 3 (ts-1). Ultraviolet-irradiated reoviruses and double-stranded ribonucleic acids extracted from purified reovirus type 3 also induced little to no interferon in L cell cultures. Under similar conditions, MM virus proved to be an effective inducer of interferon. Exposure of L cells to interferon prior to challenge with virus (priming) failed to enhance interferon production upon subsequent challenge with reovirus although priming increased the amount of interferon produced following MM virus challenge. L cell cultures that were challenged with reovirus type 3 and subsequently with either MM or Colorado tick fever viruses produced similar titers of interferon as cell cultures that were challenged with either MM or Colorado tick fever virus alone, respectively. These data show that the presence of production of reovirus type 3 double-stranded ribonucleic acid is not sufficient for induction of interferon in L cell cultures and that additional processes which are required for induction of interferon in L cell cultures are not expressed by reovirus type 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357988"}
{"pmid": "4357990", "title": "Enhanced effect of repeated administration of bacterial vaccine against viral respiratory infection.", "content": "Enhanced effect of repeated administration of bacterial vaccine against viral respiratory infection. Administration of a standard bacterial vaccine (SBV) affords some protection against influenza infection in mice if given 4 to 5 h before inoculation of the virus. This effect was enhanced by repeated injections of SBV 7 and 14 days earlier, as measured by the length of survival, mortality rate, development of gross pneumonia, and virus multiplication in the lungs. Serum interferon levels were likewise enhanced by immunization with SBV, which may, at least in part, explain the increased preventive effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357990"}
{"pmid": "4357989", "title": "Physical separation of streptococcal nicotinamide adenine dinucleotide glycohydrolase from streptolysin O.", "content": "Physical separation of streptococcal nicotinamide adenine dinucleotide glycohydrolase from streptolysin O. Streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADase) with a molecular weight of about 55,000 and an isoelectric pH of 8.55 was isolated from crude streptolysin O (SLO) preparations. NADase differed from SLO in size, charge, and immunological behavior. Streptococcal NADase is considered to have no role in the hemolytic process because it has no hemolytic activity; conversely, partially purified SLO showed no NADase activity. The hemolytic activity of crude SLO was completely inhibited by anti-tetanolysin, whereas the NADase activity in the same reaction mixture was unaffected. Experiments involving double diffusion in agar also demonstrated immunological nonidentity of the two proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357989"}
{"pmid": "4357991", "title": "Electron transfer in gamma-irradiated complexes between aromatic amino acids and DNA derivatives.", "content": "Electron transfer in gamma-irradiated complexes between aromatic amino acids and DNA derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357991"}
{"pmid": "4357992", "title": "Letter: Free radicals in the sugar moiety of x-irradiated DNA.", "content": "Letter: Free radicals in the sugar moiety of x-irradiated DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357992"}
{"pmid": "4357993", "title": "Letter: E.s.r. of irradiated single crystals of cytosine.", "content": "Letter: E.s.r. of irradiated single crystals of cytosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357993"}
{"pmid": "4357984", "title": "The catecholamines: reappraisal of their use for acute myocardial infarction and the low cardiac output syndromes.", "content": "The catecholamines: reappraisal of their use for acute myocardial infarction and the low cardiac output syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357984"}
{"pmid": "4357994", "title": "Letter: Multiplicity effect on the survival of ultra-violet-irradiated Herpes simplex virus.", "content": "Letter: Multiplicity effect on the survival of ultra-violet-irradiated Herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357994"}
{"pmid": "4357995", "title": "The effects of derivatives of adenosine 3',5'-monophosphate on fluid secretion by the salivary glands of Calliphora.", "content": "The effects of derivatives of adenosine 3',5'-monophosphate on fluid secretion by the salivary glands of Calliphora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357995"}
{"pmid": "4357996", "title": "A simple technique for monitoring the synaptic actions of pharmacological agents.", "content": "A simple technique for monitoring the synaptic actions of pharmacological agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357996"}
{"pmid": "4357999", "title": "The action of cobalt ions on neuromuscular transmission in the frog.", "content": "The action of cobalt ions on neuromuscular transmission in the frog. 1. Cobalt ions, in concentrations of 0.05-2 mM, block neuromuscular transmission in the frog sartorius muscle.2. The reduction in the e.p.p. amplitude produced by Co(2+) is due to a decrease in the amount of transmitter released by a nerve impulse (mean quantum content). This reduction is associated with little change in the resting membrane potential of the muscle fibre or in the mean amplitude of spontaneous m.e.p.p.s.3. The reduction in evoked transmitter release produced by Co(2+) may be antagonized by elevation of the external Ca(2+) concentration. It is suggested that the antagonism between Co(2+) and Ca(2+) is competitive in nature.4. The mean dissociation constant for Co(2+) and its hypothetical membrane complex was found to be 0.18 mM. On this basis, it is concluded that Co(2+) is about 20 times more potent than Mg(2+) in suppressing evoked transmitter release.5. In contrast to the inhibitory action on evoked release, Co(2+) increases spontaneous transmitter release. However, concentrations of Co(2+) 20-60 times greater than those which decrease the e.p.p. amplitude are needed to produce a significant increase in m.e.p.p. frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357999"}
{"pmid": "4357998", "title": "The composition of maternal plasma and foetal urine after feeding and drinking in chronically catheterized ewes during the last two months of pregnancy.", "content": "The composition of maternal plasma and foetal urine after feeding and drinking in chronically catheterized ewes during the last two months of pregnancy. 1. The fluid sacs and bladders of sixteen foetuses in fourteen ewes were catheterized between 81 and 92 days gestational age and the rumens of four ewes were also catheterized.2. Between 95 and 145 days gestational age in forty-six 24 hr experiments hourly samples of maternal plasma and foetal urine were obtained and in fifteen experiments foetal fluid samples were also taken at 4- to 6-hr intervals.3. The osmolality, pH, and concentrations of sodium, potassium, chloride, glucose, fructose and urea were measured on all samples.4. During experiment there was no significant variation in the composition of amniotic or allantoic fluid. Marked changes in osmolality occurred in maternal plasma and foetal urine when ewes drank after feeding, but not in ewes that received water intrarumenally via catheter while feeding or in fasting ewes. Post-prandial changes in maternal plasma osmolality may have altered transplacental water fluxes and as a result foetal plasma volume and osmolality.5. The results suggest that the foetus alters renal water retention by varying antidiuretic hormone (ADH) secretion in response to changes in blood volume and at later gestational ages plasma osmolality as well.6. Post-prandial changes in the [Na(+)]/[K(+)] ratio of foetal urine suggested that foetal adrenocorticotrophin (ACTH) secretion is influenced by variations in foetal blood volume and glucose concentrations.7. The post-prandial changes in foetal urine composition observed here support previous suggestions (Mellor & Slater, 1972) about the role of foetal urine in foetal fluid formation which were based on gestational changes in the composition of foetal fluids and urine sampled once daily during the post-absorptive state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4357998"}
{"pmid": "4358001", "title": "Growth after adolescence.", "content": "Growth after adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358001"}
{"pmid": "4358000", "title": "Enzyme aspects of acute intermittent porphyria.", "content": "Enzyme aspects of acute intermittent porphyria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358000"}
{"pmid": "4358002", "title": "Leukocyte and placental metabolism as indices of fetal malnutrition.", "content": "Leukocyte and placental metabolism as indices of fetal malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358002"}
{"pmid": "4358004", "title": "Standardized multisegmental measurements of blood pressure for quantitative evaluation of the circulation in the limbs.", "content": "Standardized multisegmental measurements of blood pressure for quantitative evaluation of the circulation in the limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358004"}
{"pmid": "4358005", "title": "Induced hypertension in the treatment of severe foot ischemia.", "content": "Induced hypertension in the treatment of severe foot ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358005"}
{"pmid": "4358006", "title": "Criticism about the use of muscles provided with a testosterone-binding protein to evaluate the miotrophic activity of androgens.", "content": "Criticism about the use of muscles provided with a testosterone-binding protein to evaluate the miotrophic activity of androgens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358006"}
{"pmid": "4358008", "title": "Fluoride uptake from prophylactic dentifrices. I. Methods for measuring fluoride uptake in tooth enamel in vitro and in vivo.", "content": "Fluoride uptake from prophylactic dentifrices. I. Methods for measuring fluoride uptake in tooth enamel in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358008"}
{"pmid": "4358009", "title": "Fluoride uptake from prophylactic dentifrices. II. Some introductory experiments and findings concerning in vitro fluoride uptake in tooth enamel.", "content": "Fluoride uptake from prophylactic dentifrices. II. Some introductory experiments and findings concerning in vitro fluoride uptake in tooth enamel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358009"}
{"pmid": "4358007", "title": "Influence of adrenalectomy and beta-methasone on the composition of liver cell membrane.", "content": "Influence of adrenalectomy and beta-methasone on the composition of liver cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358007"}
{"pmid": "4358010", "title": "Studies on (8-14C) adenosine-5'-carboxylic acid ethyl ester. II. Incorporation of radioactivity into nucleic acids of mouse and dog.", "content": "Studies on (8-14C) adenosine-5'-carboxylic acid ethyl ester. II. Incorporation of radioactivity into nucleic acids of mouse and dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358010"}
{"pmid": "4358012", "title": "Development of second-generation schizonts, gamonts and oocysts of Eimeria bovis in bovine kidney cells.", "content": "Development of second-generation schizonts, gamonts and oocysts of Eimeria bovis in bovine kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358012"}
{"pmid": "4358015", "title": "Inappropriate renin secretion in pregnancy.", "content": "Inappropriate renin secretion in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358015"}
{"pmid": "4358014", "title": "In vitro perfusion of the human utero-tubo-ovarian unit.", "content": "In vitro perfusion of the human utero-tubo-ovarian unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358014"}
{"pmid": "4358016", "title": "An improved method for the assay of hydroxylysine.", "content": "An improved method for the assay of hydroxylysine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358016"}
{"pmid": "4358017", "title": "An enzymatic method for measuring picomole quantities of acetylcholine and choline in CNS tissue.", "content": "An enzymatic method for measuring picomole quantities of acetylcholine and choline in CNS tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358017"}
{"pmid": "4358018", "title": "Improved rapidity and precision in the determination of brain 2',3'-cyclic nucleotide 3'-phosphohydrolase.", "content": "Improved rapidity and precision in the determination of brain 2',3'-cyclic nucleotide 3'-phosphohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358018"}
{"pmid": "4358019", "title": "A sensitive fluorometric assay for monoamine oxidase activity.", "content": "A sensitive fluorometric assay for monoamine oxidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358019"}
{"pmid": "4358020", "title": "Preparative solvent partition chromatography of butyrylated cyclic AMP analogues.", "content": "Preparative solvent partition chromatography of butyrylated cyclic AMP analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358020"}
{"pmid": "4358021", "title": "Effect of cyclic AMP, theophylline and caffeine on the glucose repression of sporulation in Saccharomyces cerevisiae.", "content": "Effect of cyclic AMP, theophylline and caffeine on the glucose repression of sporulation in Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358021"}
{"pmid": "4358023", "title": "Drill biopsy of the breast--a critical analysis.", "content": "Drill biopsy of the breast--a critical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358023"}
{"pmid": "4358022", "title": "Regulation in the chemolithotroph Thiobacillus neapolitanus: fructose-1,6-diphosphatase.", "content": "Regulation in the chemolithotroph Thiobacillus neapolitanus: fructose-1,6-diphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358022"}
{"pmid": "4358025", "title": "Studies on in vitro synthesis and secretion of growth hormone and prolactin. II. Evidence against the existence of precursor molecules.", "content": "Studies on in vitro synthesis and secretion of growth hormone and prolactin. II. Evidence against the existence of precursor molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358025"}
{"pmid": "4358026", "title": "Cyclic 3',5'-adenosine monophosphate in isolated bone cells. II. Responses to adenosine and parathyroid hormone.", "content": "Cyclic 3',5'-adenosine monophosphate in isolated bone cells. II. Responses to adenosine and parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358026"}
{"pmid": "4358027", "title": "An investigation of progesterone receptors in guinea pig vagina, uterine cervix, mammary glands, pituitary and hypothalamus.", "content": "An investigation of progesterone receptors in guinea pig vagina, uterine cervix, mammary glands, pituitary and hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358027"}
{"pmid": "4358028", "title": "Mechanism of action of gonadotropin. IV. Cyclic adenosine monophosphate-dependent translocation of ovarian cytoplasmic cyclic adenosine monophosphate-binding protein and protein kinase to nuclear acceptor sites.", "content": "Mechanism of action of gonadotropin. IV. Cyclic adenosine monophosphate-dependent translocation of ovarian cytoplasmic cyclic adenosine monophosphate-binding protein and protein kinase to nuclear acceptor sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358028"}
{"pmid": "4358030", "title": "Calcitonin and the formation of 3',5'-AMP in bone and kidney.", "content": "Calcitonin and the formation of 3',5'-AMP in bone and kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358030"}
{"pmid": "4358029", "title": "Cholesterol sulfate: some aspects of its biosynthesis and uptake by tissues from blood.", "content": "Cholesterol sulfate: some aspects of its biosynthesis and uptake by tissues from blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358029"}
{"pmid": "4358032", "title": "Glucagon and epinephrine activation of adenylate cyclase and glucagon binding in Morris hepatomas.", "content": "Glucagon and epinephrine activation of adenylate cyclase and glucagon binding in Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358032"}
{"pmid": "4358031", "title": "Transfer ribonucleic acid in hepatoma tissue culture cells. II. Dexamethasone phosphate induction of tRNAphe analyzed under cell-free conditions.", "content": "Transfer ribonucleic acid in hepatoma tissue culture cells. II. Dexamethasone phosphate induction of tRNAphe analyzed under cell-free conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358031"}
{"pmid": "4358033", "title": "Changes in thyroid ribonucleic acid, ribonucleases and alkaline ribonuclease inhibitor.", "content": "Changes in thyroid ribonucleic acid, ribonucleases and alkaline ribonuclease inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358033"}
{"pmid": "4358034", "title": "Effects of prostaglandin antagonists on the induction of cyclic 3',5'-adenosine monophosphate formation and thyroid hormone secretion in vitro.", "content": "Effects of prostaglandin antagonists on the induction of cyclic 3',5'-adenosine monophosphate formation and thyroid hormone secretion in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358034"}
{"pmid": "4358035", "title": "Cyclic-AMP and the ocular responses to norepinephrine.", "content": "Cyclic-AMP and the ocular responses to norepinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358035"}
{"pmid": "4358036", "title": "Rescue of the murine sarcoma virus genome from non-producer cells by the RD-114 type C virus.", "content": "Rescue of the murine sarcoma virus genome from non-producer cells by the RD-114 type C virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358036"}
{"pmid": "4358037", "title": "The effect of long-term exposure to DDT on CF-1 MICE.", "content": "The effect of long-term exposure to DDT on CF-1 MICE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358037"}
{"pmid": "4358038", "title": "Cell-mediated destruction of Rous sarcomas in Japanese quails.", "content": "Cell-mediated destruction of Rous sarcomas in Japanese quails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358038"}
{"pmid": "4358040", "title": "Surface antigen and polypseudopodia in abortive transformation of BHK 21 cells by polyoma virus.", "content": "Surface antigen and polypseudopodia in abortive transformation of BHK 21 cells by polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358040"}
{"pmid": "4358039", "title": "Establishment of continuous lymphoblast cultures from leukocytes of gibbons (Hylobates lar).", "content": "Establishment of continuous lymphoblast cultures from leukocytes of gibbons (Hylobates lar).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358039"}
{"pmid": "4358042", "title": "Re-exposure of human lymphoblastoid cell lines to Epstein-Barr virus.", "content": "Re-exposure of human lymphoblastoid cell lines to Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358042"}
{"pmid": "4358043", "title": "Regulation of maltodextrin phosphorylase synthesis in Escherichia coli by cyclic adenosine 3', 5'-monophosphate and glucose.", "content": "Regulation of maltodextrin phosphorylase synthesis in Escherichia coli by cyclic adenosine 3', 5'-monophosphate and glucose. Cyclic adenosine 3', 5'-monophosphate (AMP) stimulates maltodextrin phosphorylase synthesis in Escherichia coli cells induced with maltose. A maximal effect occurs at 2 to 3 mM cyclic AMP. The action of cyclic AMP is specific, inasmuch as adenosine triphosphate, 3'-AMP, 5'-AMP, adenosine, and dibutyryl cyclic AMP are inactive. Glucose, alpha-methyl glucoside, 2-deoxyglucose, and pyridoxal 5'-phosphate repress maltodextrin phosphorylase synthesis. This repression is reversed by cyclic AMP. The action of cyclic AMP appears to be at the transcriptional level, since cyclic AMP fails to stimulate phosphorylase production in induced cells in which messenger ribonucleic acid synthesis has been arrested by rifampin or by inducer removal. The two other enzymes involved in the metabolism of maltose, amylomaltase and maltose permease, are also induced in this strain of E. coli and affected by glucose and cyclic AMP in a manner similar to phosphorylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358043"}
{"pmid": "4358044", "title": "Membrane permeability and the loss of germination factor from Neurospora crassa at low water activities.", "content": "Membrane permeability and the loss of germination factor from Neurospora crassa at low water activities. Neurospora crassa conidia incubating in buffer at low water activities (a(w)) release a germination-essential component as well as 260-nm absorbing and ninhydrin-positive materials, regardless of whether an electrolyte or non-electrolyte is used to reduce a(w). Chloroform and antibiotics known to increase cell-membrane permeability have a similar effect. This suggests that membrane damage occurs in media of low a(w) and that an increase in permeability is responsible for the release of cellular components. The damage caused in media of low a(w) is nonlethal in most cases, and the conidia recover when transferred to nutrient medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358044"}
{"pmid": "4358046", "title": "Sporulation of Saccharomyces cerevisiae in the absence of a functional mitochondrial genome.", "content": "Sporulation of Saccharomyces cerevisiae in the absence of a functional mitochondrial genome. The role of the mitochondrial system during sporulation of Saccharomyces cerevisiae was studied. Addition of ethidium bromide (EthBr) to cells growing in acetate medium resulted in the quantitative (>98%) conversion of the culture to the petite genotype in one generation. The cells were respiratory active (derepressed) but contained no mitochondrial deoxyribonucleic acid (mtDNA) as demonstrated by analytical ultracentrifugation in CsCl. When transferred to acetate sporulation medium, the culture sporulated. Ascus production was only slightly below that of the control culture. Synthesis of mtDNA occurred during sporulation in the control but not in the EthBr-treated culture. Mitochondrial protein synthesis was virtually eliminated in the EthBr-treated culture. Therefore, completely derepressed cells can sporulate without a functional mitochondrial genetic system. When partially repressed cells were treated with EthBr, no ascus formation was observed after transfer to sporulation medium. Control cultures underwent respiratory adaptation in sporulation medium and then sporulated. Extensive derepression of the respiratory system is thus required for sporulation, and this adaptation is dependent on a functional mitochondrial system. Our results suggest that once the cells are fully derepressed no mitochondrial genetic information has to be expressed during meiosis and ascus formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358046"}
{"pmid": "4358045", "title": "Lactose and D-galactose metabolism in group N streptococci: presence of enzymes for both the D-galactose 1-phosphate and D-tagatose 6-phosphate pathways.", "content": "Lactose and D-galactose metabolism in group N streptococci: presence of enzymes for both the D-galactose 1-phosphate and D-tagatose 6-phosphate pathways. Group N streptococci possess enzymes for the metabolism of d-galactose through both the d-galactose 1-phosphate pathway (Leloir pathway) and the d-tagatose 6-phosphate pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358045"}
{"pmid": "4358047", "title": "Germination of yeast spores lacking mitochondrial deoxyribonucleic acid.", "content": "Germination of yeast spores lacking mitochondrial deoxyribonucleic acid. A population of petite ascospores (mitochondrial deoxyribonucleic acid [mtDNA]-less), produced by brief ethidium bromide (EthBr) mutagenesis prior to transfer to sporulation medium, was used to examine the role of the mitochondrial genetic system on germination and outgrowth in Saccharomyces cerevisiae. Petite ascospores, which are morphologically indistinguishable by phase-contrast microscopy from wild-type spores, germinate and proceed through outgrowth at a rate and extent only slightly less than that of wild-type spores. Both developmental processes occurred in the absence of mtDNA synthesis and measurable cytochrome oxidase activity. These results indicate that neither respiration nor a functional mitochondrial genome are required for germination and outgrowth. The properties of the petite clones were typical of petites formed during vegetative growth. Individual sporal clones differed markedly from each other in suppressiveness. Petite sporal clones which exhibited a high degree of supressiveness also contained a reduced but detectable amount of mtDNA of altered buoyant density. One clone contained a unique mtDNA with a buoyant density higher than that of wild-type mtDNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358047"}
{"pmid": "4358048", "title": "Differential diagnosis of chronic orofacial pain.", "content": "Differential diagnosis of chronic orofacial pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358048"}
{"pmid": "4358049", "title": "Disabling neuropathy associated with thymoma. Reversal by excision.", "content": "Disabling neuropathy associated with thymoma. Reversal by excision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358049"}
{"pmid": "4358053", "title": "Letter: Abdominal pain in hyperlipoproteinemia.", "content": "Letter: Abdominal pain in hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358053"}
{"pmid": "4358054", "title": "The nitroblue tetrazolium reduction test versus conventional hematology in the diagnosis of bacterial infection.", "content": "The nitroblue tetrazolium reduction test versus conventional hematology in the diagnosis of bacterial infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358054"}
{"pmid": "4358055", "title": "Zoster immune globulin. A further assessment.", "content": "Zoster immune globulin. A further assessment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358055"}
{"pmid": "4358056", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 4-1974.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 4-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358056"}
{"pmid": "4358057", "title": "Evidence for a junctional effect of lead on neuromuscular function.", "content": "Evidence for a junctional effect of lead on neuromuscular function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358057"}
{"pmid": "4358058", "title": "About the neurological sequelae of herniated intravertebral disc.", "content": "About the neurological sequelae of herniated intravertebral disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358058"}
{"pmid": "4358059", "title": "Proceedings: Human leukocyte antigens and ABO blood groups in gestational trophoblastic neoplasms.", "content": "Proceedings: Human leukocyte antigens and ABO blood groups in gestational trophoblastic neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358059"}
{"pmid": "4358060", "title": "Proceedings: Hormonal relations of endometrial cancer.", "content": "Proceedings: Hormonal relations of endometrial cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358060"}
{"pmid": "4358061", "title": "Proceedings: Xeroradiography of the breast.", "content": "Proceedings: Xeroradiography of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358061"}
{"pmid": "4358062", "title": "Proceedings: Lectin monitored surface changes in transformed and mitotic normal cells.", "content": "Proceedings: Lectin monitored surface changes in transformed and mitotic normal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358062"}
{"pmid": "4358063", "title": "Proceedings: Genetics and the cancer cell: cell growth regulation.", "content": "Proceedings: Genetics and the cancer cell: cell growth regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358063"}
{"pmid": "4358064", "title": "Proceedings: Tumors of the adrenal cortex and Cushing's syndrome.", "content": "Proceedings: Tumors of the adrenal cortex and Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358064"}
{"pmid": "4358065", "title": "Proceedings: Islets of Langerhans.", "content": "Proceedings: Islets of Langerhans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358065"}
{"pmid": "4358066", "title": "Proceedings: Genetics and the cancer cell: cell genetics and growth of endogenous viruses.", "content": "Proceedings: Genetics and the cancer cell: cell genetics and growth of endogenous viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358066"}
{"pmid": "4358067", "title": "Proceedings: Soft part sarcomas in children--1972.", "content": "Proceedings: Soft part sarcomas in children--1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358067"}
{"pmid": "4358069", "title": "Proceedings: Survival of lung cancer patients vis-à-vis therapy and cell type.", "content": "Proceedings: Survival of lung cancer patients vis-à-vis therapy and cell type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358069"}
{"pmid": "4358068", "title": "Proceedings: The national Wilms' tumor study: a progress report.", "content": "Proceedings: The national Wilms' tumor study: a progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358068"}
{"pmid": "4358070", "title": "Proceedings: Carcinoma of the lung at the New York Hospital-Cornell Medical Center (1964-1968).", "content": "Proceedings: Carcinoma of the lung at the New York Hospital-Cornell Medical Center (1964-1968).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358070"}
{"pmid": "4358071", "title": "Proceedings: Immunological investigations on human brain tumor patients.", "content": "Proceedings: Immunological investigations on human brain tumor patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358071"}
{"pmid": "4358072", "title": "Proceedings: Chemotherapy of soft-tissue sarcomas.", "content": "Proceedings: Chemotherapy of soft-tissue sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358072"}
{"pmid": "4358073", "title": "Synaptic transmission between photoreceptors and horizontal cells in the turtle retina.", "content": "Synaptic transmission between photoreceptors and horizontal cells in the turtle retina. Low calcium, high magnesium, and cobalt hyperpolarize the horizontal cell membrane and suppress the response to light, but only partially affect the response of receptor cells. These observations are consistent with the interpretation that a depolarizing transmitter is released by photoreceptors in darkness. The hyperpolarizing response to light of the horizontal cells would then result from a reduction in the amount of transmitter released.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358073"}
{"pmid": "4358074", "title": "High-frequency C-type virus induction by inhibitors of protein synthesis.", "content": "High-frequency C-type virus induction by inhibitors of protein synthesis. When inhibitors of protein synthesis are added to BALB/c mouse cells in culture, induction of naturally integrated C-type RNA virus occurs in a high percentage of cells. The action of protein synthesis inhibitors differs from that of halogenated pyrimidines, another class of virus inducers, in their effects on biologically distinguishable viruses. The use of such inhibitors to study integrated virus expression provides a means for studying gene regulation in mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358074"}
{"pmid": "4358075", "title": "Reduction of ferricytochrome c by some free radical agents.", "content": "Reduction of ferricytochrome c by some free radical agents. Fast pulse radiolysis and kinetic spectroscopy were used to rapidly generate a variety of free radicals in situ and study their reactions with ferricytochrome c in the time range 10(-6) to 1 second. The radicals included t-butanol, which is inert to ferricytochrome c; malate, lactate, and ethanol, which react with it relatively slowly but are completely utilized in reducing it to ferrocytochrome c; and hydrated electrons and hydrogen atoms, which react with it very rapidly but yield ferrocytochrome c only in part, showing intramolecular consecutive reactions and further attack on the ferrocytochrome c protein. From a detailed comparison between malate and hydrogen atoms it is argued that malate reacts directly and selectively with a specific part of the ferricytochrome c surface while hydrogen atoms react with other parts of the protein too, yielding radicals which in part transfer intramolecularly to yield ferrocytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358075"}
{"pmid": "4358077", "title": "Proton relaxation rates of water in brain and brain tumors.", "content": "Proton relaxation rates of water in brain and brain tumors. The distribution of relaxation rates of water in \"normal\" (autopsy) samples of canine and human brain shows considerable overlap with that for brain tumor samples. The following ranges of values for the spin-spin relaxation rates were observed: for normal brain gray matter, 8.6 to 11.3 sec(-1) (mean, 9.5 sec(-1)); for normal brain white matter, 13.3 to 15.7 sec(-1) (mean, 15.5 sec(-1)); for six types of malignant tumor, 4.8 to 13.4 sec(-1) (mean, 9.3 sec(-1)); for five types of benign tumor, 7.1 to 16.4 sec(-1) (mean, 11.5 sec(-1)). Spin-lattice relaxation rates showed a similar pattern. At least two nonexchanging water components with different relaxation rates were indicated by the analysis of the spin-spin relaxation measurements for the white matter samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358077"}
{"pmid": "4358076", "title": "Protein kinase translocation as an early event in the hormonal control of uterine contraction.", "content": "Protein kinase translocation as an early event in the hormonal control of uterine contraction. beta-Adrenergic stimulation with isoproterenol inhibits contractility, increases cyclic adenosine monophosphate (AMP) concentration, decreases the concentration of unsaturated cyclic AMP receptor sites, and increases cyclic AMP-independent kinase in the uterus of ovariectomized rats. The total soluble kinase activity is reduced. The protein kinase activity lost from the cytosol was translocated to the microsomal fraction mostly in a cyclic AMP-independent form, suggesting a particulate substrate for the activated enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358076"}
{"pmid": "4358082", "title": "Rapid adiabatic passage EPR of ferricytochrome c: signal enhancement and determination of the spin-lattice relaxation time.", "content": "Rapid adiabatic passage EPR of ferricytochrome c: signal enhancement and determination of the spin-lattice relaxation time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358082"}
{"pmid": "4358081", "title": "Thyroid optic neuropathy: to decompress or not?", "content": "Thyroid optic neuropathy: to decompress or not?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358081"}
{"pmid": "4358083", "title": "Studies of the metal sites of copper proteins. V. A model compound for the copper site of superoxide dismutase.", "content": "Studies of the metal sites of copper proteins. V. A model compound for the copper site of superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358083"}
{"pmid": "4358084", "title": "Conformational studies on modified proteins and peptides. VII. Conformation of epsilon-prototoxin and epsilon-toxin from Clostridium perfringens. Conformational changes associated with toxicity.", "content": "Conformational studies on modified proteins and peptides. VII. Conformation of epsilon-prototoxin and epsilon-toxin from Clostridium perfringens. Conformational changes associated with toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358084"}
{"pmid": "4358085", "title": "Preparation of photo-affinity probes for the insulin receptor site in adipose and liver cell membranes.", "content": "Preparation of photo-affinity probes for the insulin receptor site in adipose and liver cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358085"}
{"pmid": "4358078", "title": "Cholinergic mechanism in the cerebrovascular action of carbon dioxide.", "content": "Cholinergic mechanism in the cerebrovascular action of carbon dioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358078"}
{"pmid": "4358086", "title": "Phosphorylation of surface proteins of HeLa cells using an exogenous protein kinase and (gamma-32P)ATP.", "content": "Phosphorylation of surface proteins of HeLa cells using an exogenous protein kinase and (gamma-32P)ATP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358086"}
{"pmid": "4358087", "title": "A partially purified membrane protein specific to the brain.", "content": "A partially purified membrane protein specific to the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358087"}
{"pmid": "4358088", "title": "Monoiodinated angiotensins: preparation and characterization by polyacrylamide gel electrophoresis and isoelectric focusing.", "content": "Monoiodinated angiotensins: preparation and characterization by polyacrylamide gel electrophoresis and isoelectric focusing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358088"}
{"pmid": "4358089", "title": "Electron nuclear double resonance studies on heme proteins: interaction of the electron spin with the 57Fe3+ nucleus in metmyoglobin and methemoglobin.", "content": "Electron nuclear double resonance studies on heme proteins: interaction of the electron spin with the 57Fe3+ nucleus in metmyoglobin and methemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358089"}
{"pmid": "4358091", "title": "Triphosphoinositide phosphodiesterase in a protozoan-Crithidia fasciculata.", "content": "Triphosphoinositide phosphodiesterase in a protozoan-Crithidia fasciculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358091"}
{"pmid": "4358090", "title": "Analysis of polar parts of phospholipids. N-demethylation of choline-containing lipids for gas chromatography and mass spectrometry.", "content": "Analysis of polar parts of phospholipids. N-demethylation of choline-containing lipids for gas chromatography and mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358090"}
{"pmid": "4358092", "title": "Improved conditions for the preservation and extraction of polyphosphoinositides.", "content": "Improved conditions for the preservation and extraction of polyphosphoinositides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358092"}
{"pmid": "4358093", "title": "The subcellular distribution of polyphosphoinositides in myelinated and unmyelinated rat brain.", "content": "The subcellular distribution of polyphosphoinositides in myelinated and unmyelinated rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358093"}
{"pmid": "4358094", "title": "Blood group A active ceramide hexasaccharide lacking N-acetylglucosamine isolated from hog stomach mucosa.", "content": "Blood group A active ceramide hexasaccharide lacking N-acetylglucosamine isolated from hog stomach mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358094"}
{"pmid": "4358095", "title": "The influence of extracellular calcium ion on hormone-activated lipolysis.", "content": "The influence of extracellular calcium ion on hormone-activated lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358095"}
{"pmid": "4358096", "title": "The detection of linoleic acid radicals in the anaerobic reaction of lipoxygenase.", "content": "The detection of linoleic acid radicals in the anaerobic reaction of lipoxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358096"}
{"pmid": "4358097", "title": "Attempts to reverse the effects of disuse in the lateral geniculate nucleus of the cat.", "content": "Attempts to reverse the effects of disuse in the lateral geniculate nucleus of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358097"}
{"pmid": "4358098", "title": "Influence of L-DOPA on transmission in long ascending propriospinal pathways in the cat.", "content": "Influence of L-DOPA on transmission in long ascending propriospinal pathways in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358098"}
{"pmid": "4358100", "title": "Effects of stimulation of the vestibular labyrinth on intracellular responses of spinal motoneurons in the pigeon.", "content": "Effects of stimulation of the vestibular labyrinth on intracellular responses of spinal motoneurons in the pigeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358100"}
{"pmid": "4358099", "title": "Restoration of locomotor activity in mice by low L-DOPA doses after suppression by alpha-methyltyrosine but not by reserpine.", "content": "Restoration of locomotor activity in mice by low L-DOPA doses after suppression by alpha-methyltyrosine but not by reserpine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358099"}
{"pmid": "4358101", "title": "Tetrodotoxin resistant electrically excitable responses of receptor cells.", "content": "Tetrodotoxin resistant electrically excitable responses of receptor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358101"}
{"pmid": "4358104", "title": "Demonstration of hyper-alpha-lipoproteinemia in three diabetic patients.", "content": "Demonstration of hyper-alpha-lipoproteinemia in three diabetic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358104"}
{"pmid": "4358106", "title": "The evolution of EEG features in infantile spasms: a prospective study.", "content": "The evolution of EEG features in infantile spasms: a prospective study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358106"}
{"pmid": "4358107", "title": "The syndrome of inappropriate secretion of antidiuretic hormone (SIADH).", "content": "The syndrome of inappropriate secretion of antidiuretic hormone (SIADH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358107"}
{"pmid": "4358109", "title": "The effect of pertussis adjuvant on antibody production: the need for thymus-dependent lymphocytes.", "content": "The effect of pertussis adjuvant on antibody production: the need for thymus-dependent lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358109"}
{"pmid": "4358110", "title": "Isolation and characterization of an adherent, 8-azaguanine resistant variant of the Burkitt lymphoma cell line, Raji.", "content": "Isolation and characterization of an adherent, 8-azaguanine resistant variant of the Burkitt lymphoma cell line, Raji.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358110"}
{"pmid": "4358112", "title": "Enzyme microelectrophoresis of cell colonies.", "content": "Enzyme microelectrophoresis of cell colonies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358112"}
{"pmid": "4358111", "title": "Acrosomal ATPase in starfish and bivalve mollusk spermatozoa.", "content": "Acrosomal ATPase in starfish and bivalve mollusk spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358111"}
{"pmid": "4358113", "title": "Endocytosis in Chinese hamster fibroblasts. Inhibition by glucose.", "content": "Endocytosis in Chinese hamster fibroblasts. Inhibition by glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358113"}
{"pmid": "4358105", "title": "The brain and sodium homeostasis.", "content": "The brain and sodium homeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358105"}
{"pmid": "4358114", "title": "Activation of phosphorylase in sea urchin eggs by Ca2+ and cyclic 3'5'-AMP. A possible mechanism of the regulation of its activity at fertilization.", "content": "Activation of phosphorylase in sea urchin eggs by Ca2+ and cyclic 3'5'-AMP. A possible mechanism of the regulation of its activity at fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358114"}
{"pmid": "4358115", "title": "Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion.", "content": "Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358115"}
{"pmid": "4358116", "title": "Studies of inhibitors of bone marrow colony formation in normal human sera and during a viral infection.", "content": "Studies of inhibitors of bone marrow colony formation in normal human sera and during a viral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358116"}
{"pmid": "4358117", "title": "Preferential retention of the human chromosome C-7 in human-(thymidine kinase deficient) mouse hybrid cells.", "content": "Preferential retention of the human chromosome C-7 in human-(thymidine kinase deficient) mouse hybrid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358117"}
{"pmid": "4358118", "title": "Identification of N,N-dimethyltryptamine, 5-methoxy-N,N-dimethyltryptamine and bufotenin by cellulose TLC.", "content": "Identification of N,N-dimethyltryptamine, 5-methoxy-N,N-dimethyltryptamine and bufotenin by cellulose TLC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358118"}
{"pmid": "4358119", "title": "Medical problems in chronic alcoholic men.", "content": "Medical problems in chronic alcoholic men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358119"}
{"pmid": "4358120", "title": "Effects of idoxuridine on Herpesvirus hominis encephalitis and disseminated infections in marmosets.", "content": "Effects of idoxuridine on Herpesvirus hominis encephalitis and disseminated infections in marmosets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358120"}
{"pmid": "4358122", "title": "Role of mosquitoes in the spread of smallpox.", "content": "Role of mosquitoes in the spread of smallpox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358122"}
{"pmid": "4358121", "title": "Adenovirus vaccines in military recruit populations: a cost-benefit analysis.", "content": "Adenovirus vaccines in military recruit populations: a cost-benefit analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358121"}
{"pmid": "4358123", "title": "Effect of proteolytic enzymes on the infectivity of a number of herpesviruses.", "content": "Effect of proteolytic enzymes on the infectivity of a number of herpesviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358123"}
{"pmid": "4358124", "title": "The two sites of penicillin action in Escherichia coli.", "content": "The two sites of penicillin action in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358124"}
{"pmid": "4358125", "title": "Viruses causing common respiratory infection in man. IV. Reoviruses and Adenoviruses.", "content": "Viruses causing common respiratory infection in man. IV. Reoviruses and Adenoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358125"}
{"pmid": "4358126", "title": "Xeroderma pigmentosum cell susceptibility to SV40 virus transformation: lack of effect of low dosage ultraviolet radiation in enhancing viral-induced transformation.", "content": "Xeroderma pigmentosum cell susceptibility to SV40 virus transformation: lack of effect of low dosage ultraviolet radiation in enhancing viral-induced transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358126"}
{"pmid": "4358127", "title": "On the origin of oligomer forms of polyoma DNA.", "content": "On the origin of oligomer forms of polyoma DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358127"}
{"pmid": "4358128", "title": "Editorial: Role of the megakaryocyte and platelet in the leukemic process in mice and men--a review and hypothesis.", "content": "Editorial: Role of the megakaryocyte and platelet in the leukemic process in mice and men--a review and hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358128"}
{"pmid": "4358129", "title": "Factors affecting glycogen levels in HeLa cells: prednisolone and adenine nucleotides.", "content": "Factors affecting glycogen levels in HeLa cells: prednisolone and adenine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358129"}
{"pmid": "4358130", "title": "Antibodies to Epstein-Barr virus-related antigens in nasopharyngeal carcinoma. Comparison of active cases with long-term survivors.", "content": "Antibodies to Epstein-Barr virus-related antigens in nasopharyngeal carcinoma. Comparison of active cases with long-term survivors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358130"}
{"pmid": "4358131", "title": "Lung cancer in women: present and future trends.", "content": "Lung cancer in women: present and future trends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358131"}
{"pmid": "4358132", "title": "Prevalence of type-C virus and antibodies in normal cats and cats with neoplasia.", "content": "Prevalence of type-C virus and antibodies in normal cats and cats with neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358132"}
{"pmid": "4358133", "title": "Virus-chemical carcinogenesis: a possible viral immunologic influence on 3-methylcholanthrene sarcoma induction.", "content": "Virus-chemical carcinogenesis: a possible viral immunologic influence on 3-methylcholanthrene sarcoma induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358133"}
{"pmid": "4358134", "title": "A new group of oncogenic viruses: reticuloendotheliosis, chick syncytial, duck infectious anemia, and spleen necrosis viruses.", "content": "A new group of oncogenic viruses: reticuloendotheliosis, chick syncytial, duck infectious anemia, and spleen necrosis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358134"}
{"pmid": "4358135", "title": "Detection of hamster type-C virus antigens by the passive hemagglutination technique.", "content": "Detection of hamster type-C virus antigens by the passive hemagglutination technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358135"}
{"pmid": "4358137", "title": "Oncogenicity of Herpesvirus ateles in monkeys.", "content": "Oncogenicity of Herpesvirus ateles in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358137"}
{"pmid": "4358136", "title": "Studies of FBJ osteosarcoma virus in tissue culture. I. Biologic characteristics of the \"C\"-type viruses.", "content": "Studies of FBJ osteosarcoma virus in tissue culture. I. Biologic characteristics of the \"C\"-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358136"}
{"pmid": "4358138", "title": "Oncogenic potential of murine C-type RNA virus passaged directly from naturally occurring tumors of the BALB-cCr mouse.", "content": "Oncogenic potential of murine C-type RNA virus passaged directly from naturally occurring tumors of the BALB-cCr mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358138"}
{"pmid": "4358139", "title": "Comparative characterization of a C-type virus-producing cell line (VSW) and a virus-free cell line (VH2) from Vipera russelli.", "content": "Comparative characterization of a C-type virus-producing cell line (VSW) and a virus-free cell line (VH2) from Vipera russelli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358139"}
{"pmid": "4358140", "title": "Abelson virus activity in mice and rats neutralized with anti-Rauscher virus serum.", "content": "Abelson virus activity in mice and rats neutralized with anti-Rauscher virus serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358140"}
{"pmid": "4358141", "title": "Antibodies reacting to Simian virus 40 T antigen in human sera.", "content": "Antibodies reacting to Simian virus 40 T antigen in human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358141"}
{"pmid": "4358143", "title": "Kinetics of nitrosation of the amino acids proline, hydroxyproline, and sarcosine.", "content": "Kinetics of nitrosation of the amino acids proline, hydroxyproline, and sarcosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358143"}
{"pmid": "4358142", "title": "Induction of tubular structures in the endoplasmic reticulum of human lymphoid cells by treatment with 5-bromo-2'-deoxyuridine.", "content": "Induction of tubular structures in the endoplasmic reticulum of human lymphoid cells by treatment with 5-bromo-2'-deoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358142"}
{"pmid": "4358144", "title": "Toxic metabolites released from rat hepatoma cells in culture. I. Effects of metabolites of hepatomas on various cells.", "content": "Toxic metabolites released from rat hepatoma cells in culture. I. Effects of metabolites of hepatomas on various cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358144"}
{"pmid": "4358145", "title": "Cultivation and characterization of BALB-cfC3H mammary tumor cell lines.", "content": "Cultivation and characterization of BALB-cfC3H mammary tumor cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358145"}
{"pmid": "4358146", "title": "Selection of tumor-host cell hybrids from polyoma virus- and methylcholanthrene-induced sarcomas.", "content": "Selection of tumor-host cell hybrids from polyoma virus- and methylcholanthrene-induced sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358146"}
{"pmid": "4358147", "title": "Histopathology of tumor regression after intralesional injection of Mycobacterium bovis. IV. Development of immunity to tumor cells and BCG.", "content": "Histopathology of tumor regression after intralesional injection of Mycobacterium bovis. IV. Development of immunity to tumor cells and BCG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358147"}
{"pmid": "4358149", "title": "In vivo inoculation of RNA C-type viruses inducing regression of experimental solid tumors.", "content": "In vivo inoculation of RNA C-type viruses inducing regression of experimental solid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358149"}
{"pmid": "4358148", "title": "High resolution autoradiographic study of the kinetics of development of Rous sarcoma virus (Schmidt-Ruppin strain). V. Estimation of the time of synthesis of virus-associated DNA.", "content": "High resolution autoradiographic study of the kinetics of development of Rous sarcoma virus (Schmidt-Ruppin strain). V. Estimation of the time of synthesis of virus-associated DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358148"}
{"pmid": "4358150", "title": "Antibody patterns to Herpesvirus saimiri-induced antigens in owl monkeys.", "content": "Antibody patterns to Herpesvirus saimiri-induced antigens in owl monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358150"}
{"pmid": "4358152", "title": "Transplacental effects of 1-ethyl-1-nitrosourea in inbred strains of mice. 3. Association between infectious or subinfectious endogenous type-C RNA tumor virus expression and chemically induced tumorigenesis.", "content": "Transplacental effects of 1-ethyl-1-nitrosourea in inbred strains of mice. 3. Association between infectious or subinfectious endogenous type-C RNA tumor virus expression and chemically induced tumorigenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358152"}
{"pmid": "4358151", "title": "Interactions of early mouse embryos with oncogenic viruses--simian virus 40 and polyoma. I. Ultrastructural studies.", "content": "Interactions of early mouse embryos with oncogenic viruses--simian virus 40 and polyoma. I. Ultrastructural studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358151"}
{"pmid": "4358153", "title": "Expression of A- and C-type particles in early mouse embryos.", "content": "Expression of A- and C-type particles in early mouse embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358153"}
{"pmid": "4358154", "title": "Oral excretion of Herpesvirus saimiri in captive squirrel monkeys and incidence of infection in feral squirrel monkeys.", "content": "Oral excretion of Herpesvirus saimiri in captive squirrel monkeys and incidence of infection in feral squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358154"}
{"pmid": "4358155", "title": "Transplantation of chemically induced metastatic mucinous adenocarcinomas of the jejunum and colon in rats.", "content": "Transplantation of chemically induced metastatic mucinous adenocarcinomas of the jejunum and colon in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358155"}
{"pmid": "4358156", "title": "5'-Nucleotide phosphodiesterase isoenzyme and hepatic cancer in NCI-Mayo Clinic panel sera.", "content": "5'-Nucleotide phosphodiesterase isoenzyme and hepatic cancer in NCI-Mayo Clinic panel sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358156"}
{"pmid": "4358157", "title": "Reassociation kinetics for Epstein-Barr virus DNA: nonhomology to mammalian DNA and homology of viral DNA in various diseases.", "content": "Reassociation kinetics for Epstein-Barr virus DNA: nonhomology to mammalian DNA and homology of viral DNA in various diseases. The number of Epstein-Barr virus (EBV) genomes per cell in established leukocytic lines and tissue specimens has been evaluated by measuring DNA-DNA reassociation kinetics with hydroxyapatite chromatography. Under the proper conditions, this method is sufficiently sensitive to detect EBV DNA in the amount of 0.1 genome per cell. All the samples tested that have been suspected to be without EBV DNA by cRNA hybridization proved negative by this more sensitive specific analysis. These included Hela and Hep2 cells, a negative case of Burkitt's lymphoma, two negative cases of nasopharyngeal carcinoma, and two established human leukocytic lines. Homology tests conducted with single-strand-specific nuclease S1 indicated that the viral DNA from a nasopharyngeal carcinoma and infectious mononucleosis were more than 90% homologous to EBV DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358157"}
{"pmid": "4358158", "title": "Alteration in tRNA methyltransferase activity in mengovirus infection: host range specificity.", "content": "Alteration in tRNA methyltransferase activity in mengovirus infection: host range specificity. The tRNA methyltransferase activity in mengovirus-infected L cells, HeLa cells, and Maden Derby bovine kidney cells has been examined during the course of infection. The first two cell lines yield a productive infection, but have different kinetics of inhibition of host RNA synthesis, whereas the bovine kidney cells are a restrictive host. In infected L cells the enzymes show altered capacity and base specificity throughout the infection. In infected HeLa cells and in infected bovine kidney cells less marked changes were seen. No inhibitors or activators of the enzymes were detected in any of the infected cell lines. Labeling experiments in infected cells indicated that in infected L cells synthesis of RNA was inhibited to a greater degree than was methylation of RNA. The consequence of this would be a hypermethylation of RNA. The methylated derivatives synthesized in infected L cells showed changes in relative proportions. Infection of HeLa cells and bovine kidney cells did not show such marked effects on methylation of RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358158"}
{"pmid": "4358159", "title": "Cell-free translation of paramyxovirus messenger RNA.", "content": "Cell-free translation of paramyxovirus messenger RNA. Polypeptides corresponding in electrophoretic mobility to virion polypeptides 1, 3, and 5 were made in a reticulocyte cell-free system to which 18S RNA from Sendai virus-infected cells was added. Immune precipitation was used to select relevant polypeptides from endogenous products. The cell-free product corresponding to virion polypeptide 3 (the nucleocapsid structure unit) was the most abundant; its tryptic peptides comigrated electrophoretically with tryptic peptides of polypeptide 3 isolated from virions. Other sedimenting classes of RNA from infected cells were tested; only the 28S fraction showed slight activity. Virion 50S RNA was inactive. These findings support the hypothesis that complementary RNA transcripts of paramyxovirion RNA are the templates for viral proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358159"}
{"pmid": "4358162", "title": "Structural characteristics and nucleotide sequence analysis of genomic RNA from RD-114 virus and feline RNA tumor viruses.", "content": "Structural characteristics and nucleotide sequence analysis of genomic RNA from RD-114 virus and feline RNA tumor viruses. The results of molecular hybridization experiments have demonstrated that the RNA genome of RD-114 virus has extensive nucleotide sequence homology with the RNA genome of Crandell virus, an endogenous type C virus of cats, but only limited homology with the RNA genomes of feline sarcoma virus and feline leukemia virus. The genomic RNAs of RD-114 virus and Crandell virus also had identical sedimentation coefficients of 50S. A structural rearrangement of genomic RNA did not exist within released RD-114 virions, whereas a structural rearrangement of genomic RNA did occur within feline sarcoma virions and feline leukemia virions after release from virus-producing cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358162"}
{"pmid": "4358160", "title": "Strandedness and complementarity of DNA from long-term RNA-dependent DNA polymerase reactions of Soehner-Dmochowski murine sarcoma virus.", "content": "Strandedness and complementarity of DNA from long-term RNA-dependent DNA polymerase reactions of Soehner-Dmochowski murine sarcoma virus. The DNA product of the endogenously instructed RNA-dependent DNA polymerase reaction of murine sarcoma virus continued to be synthesized for as long as 64 h in the presence of 0.008% Triton X-100. Higher detergent concentrations and actinomycin D inhibited DNA product synthesis. The DNA product from long-term polymerase reactions consisted of small DNA fragments as shown by sedimentation in alkaline sucrose gradients. The enzymatic DNA product was separated into a slow sedimenting fraction and a fast sedimenting fraction by rate-zonal centrifugation. Fast sedimenting DNA was the predominant fraction made in viral polymerase reactions containing 262 mM NaCl. By using a combination of S-1 nuclease and pancreatic RNase A, the amount of single-stranded DNA, double-stranded DNA, and DNA-RNA hybrid present in the slow-sedimenting and fast-sedimenting fractions was determined. Under standard polymerase conditions of 70 mM NaCl, single-stranded DNA was the major form of DNA found in both fractions. In contrast, the prevalent form of DNA made in the presence of 262 mM NaCl was DNA-RNA hybrid. Hybridization studies in which either S-1 nuclease or pancreatic RNase A was used to measure hybrid formation demonstrated not only that the DNA product was complementary in base sequence to the RNA genome, but also that at least 79 to 84% of the RNA genome was transcribed into complementary DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358160"}
{"pmid": "4358161", "title": "Polyoma pseudovirions. II. Influence of host cell on pseudovirus production.", "content": "Polyoma pseudovirions. II. Influence of host cell on pseudovirus production. The type of host cell influenced the relative amounts of pseudovirions and polyoma virions produced. The infection of primary mouse embryo cells resulted in the production of particles that were predominantly pseudovirions. Infection of baby mouse kidney or 3T3D cells yielded mainly infectious polyoma virus. The length of time that infection was allowed to continue also affected the amount of pseudovirions relative to polyoma virions. The longer the viral infection was allowed to proceed, the greater the quantity of pseudovirions produced. Pseudovirion production could be correlated with the fragmentation of host cell DNA to a size of approximately 3 x 10(6) daltons. The fragmentation of host cell DNA was much more extensive in primary mouse embryo cells than in the other cell types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358161"}
{"pmid": "4358163", "title": "Cell surface antigens associated with murine leukemia virus: definition of the GL and GT antigenic systems.", "content": "Cell surface antigens associated with murine leukemia virus: definition of the GL and GT antigenic systems. Two new serological specificities were identified on the surface of murine leukemia virus (MuLV)-infected cells by direct and absorption immunofluorescence tests. Both antigens were detected with antisera prepared in rats that were growing transplants of syngenic MuLV-induced leukemias. Antigen G(L) was defined with the AKR leukemia K36 as the test cell; antigen G(T) was defined with the W/Fu leukemia C58(NT)D as the test cell. G(L) and G(T) antigens were serologically and genetically independent of the MuLV-induced Gross and G(IX) cell-surface antigens. G(L) and G(T) antigens were found in normal lymphoid cells of mice from high-leukemic strains, but not in lymphoid tissues of mice from most low-leukemic strains. Tumors and leukemias of mice of low-leukemic strains often were G(L) and G(T) positive. Similarly, infection of normal cells with MuLV resulted in expression of G(L) and G(T). With ferritin-labeled antibody the G(L) and G(T) antigens were observed on virus-free segments of the cell surface. Genetically, G(L) and G(T) antigens were each controlled by two dominant unlinked genes in AKR mice; these same antigens were each controlled by three or more dominant unlinked genes in C58 mice. Penetrance of G(L) and G(T) regulatory genes was dependent upon the Fv-1 genotype of the host. Expression of G(L) antigen was closely associated with virus production, whereas expression of G(T) antigen was less closely associated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358163"}
{"pmid": "4358164", "title": "Morphogenesis of poliovirus. II. Demonstration of a new intermediate, the proviron.", "content": "Morphogenesis of poliovirus. II. Demonstration of a new intermediate, the proviron. Poliovirus-infected cells contain a previously unrecognized particle which appears to be an intermediate in virion synthesis and therefore has been named proviron. It sediments at about 125S, contains the three procapsid proteins, VP-0, VP-1, and VP-3, and has 35S viral RNA. It is disrupted both by sodium dodecyl sulfate and EDTA but the RNA resists digestion by ribonuclease. Pulsechase experiments and studies employing the virus-specific inhibitor, guanidine, all indicate that the proviron is formed by combination of newly made RNA with the procapsid. Cleavage of VP-0 to form VP-2 and VP-4 follows formation of the provirion and would be the final step in poliovirus morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358164"}
{"pmid": "4358165", "title": "Morphogenesis of poliovirus 3. Formation of provirion in cell-free extracts.", "content": "Morphogenesis of poliovirus 3. Formation of provirion in cell-free extracts. Formation of an apparent virion precursor, the provirion, can be demonstrated in cytoplasmic extracts of poliovirus-infected HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358165"}
{"pmid": "4358166", "title": "Simian virus 40-host cell interactions. I. Temperature-sensitive regulation of SV40 T antigen in 3T3 mouse cells transformed by the ts*101 temperature-sensitive early mutant of SV40.", "content": "Simian virus 40-host cell interactions. I. Temperature-sensitive regulation of SV40 T antigen in 3T3 mouse cells transformed by the ts*101 temperature-sensitive early mutant of SV40. BALB/3T3 and Swiss/3T3 mouse cells transformed at permissive temperature (33 C) by the early temperature-sensitive mutant of simian virus 40 (SV40), ts(*)101, exhibited a temperature-dependent modulation of SV40 tumor (T) antigen as assayed by immunofluorescence. The percentage of T antigen-positive nuclei in ts(*)101 transformed cells was reduced at restrictive temperature (39 C) when compared to 33 C and to wild-type SV40 transformed cells at either 33 C or 39 C. The percentage of T antigen-positive nuclei in ts(*)101 transformed cells returned to the 33 C control level when the cells were shifted from 39 to 33 C. The ts(*)101 transformed cells could be superinfected with wild-type, but not ts(*)101, virions at 39 C as assayed by an increase in T antigen-positive nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358166"}
{"pmid": "4358167", "title": "RNA-dependent RNA polymerase in nuclei of cells infected with influenza virus.", "content": "RNA-dependent RNA polymerase in nuclei of cells infected with influenza virus. Nuclei purified from chicken embryo fibroblast cells infected with influenza (fowl plague) virus contain an RNA-dependent RNA polymerase. The in vitro activity of this enzyme is insensitive to actinomycin D, and is completely destroyed by preincubation with ribonuclease. Enzyme induction is prevented if cells are treated with actinomycin D or cycloheximide at the time of infection. RNA-dependent RNA polymerase activity increases rapidly in cell nuclei from 1 h postinfection, reaches a maximum at 3 to 4 h, then declines; a similar RNA polymerase activity in the microsomal cell fraction increases from 2 h postinfection and reaches a maximum at 5 to 6 h. The characteristics of the nuclear and microsomal enzymes in vitro are similar with respect to pH and divalent cation requirements. The in vitro products of enzyme activity present in the nuclear and microsomal fractions of cells infected for 3 and 5 h were characterized by sucrose density gradient analysis, and annealing to virion RNA. The microsomal RNA polymerase product contained 67 and 93% RNA complementary to virion RNA at 3 and 5 h, respectively; for the nuclear RNA polymerase product these values were 40% in each case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358167"}
{"pmid": "4358168", "title": "Determination of the molecular weight of animal RNA viral genomes by nuclease digestions. I. Vesicular stomatitis virus and its defective T particle.", "content": "Determination of the molecular weight of animal RNA viral genomes by nuclease digestions. I. Vesicular stomatitis virus and its defective T particle. A procedure has been developed for the determination of the weight of animal RNA virus genomes using controlled nuclease digestions and computation of the moles of oligonucleotides obtained from 1 mol of RNA. Using both pancreatic RNase and RNase T(1) to digest viral RNA labeled by (3)H-uridine, (3)H-cytidine, or (3)H-guanosine, the weight of the virion RNA of vesicular stomatitis virus (VSV) is estimated as 3.82 +/- 0.14 x 10(6) whereas that of the VSV-defective T particle is estimated as 1.23 +/- 0.04 x 10(6).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358168"}
{"pmid": "4358169", "title": "RD 114 virus-specific sequences in feline cellular RNA: detection and characterization.", "content": "RD 114 virus-specific sequences in feline cellular RNA: detection and characterization. RNA extracted from cat cells contains sequences homologous to RD-114 viral RNA. The sequences are measured by molecular hybridization with a single-stranded DNA probe synthesized by the virion polymerase using the endogenous viral RNA as template. Viral-specific RNA has been detected in all cells of cat origin tested thus far, but not in cells of other animals, except for the virus-producing human rhabdomyosarcoma cell, RD-114. The extent of hybridization of the DNA probe to cellular RNA was equivalent to that obtained with viral 70S RNA indicating that an equal extent of viral specific sequences is present in all cat cells as well as in RD-114 cells. The amounts of this viral RNA reach approximately 100 copies per cell in cat cells, while virus-producing RD-114 cells contain about 1,000 copies per cell. The viral RNA is present in cat cells in two distinct sizes of about 35S and 18S, whereas in RD-114 cells virus-specific RNA is quite heterogeneous in size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358169"}
{"pmid": "4358170", "title": "Viruses as precipitants of asthmatic attacks in children.", "content": "Viruses as precipitants of asthmatic attacks in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358170"}
{"pmid": "4358171", "title": "Letter: Topical application of cyclic AMP in psoriasis.", "content": "Letter: Topical application of cyclic AMP in psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358171"}
{"pmid": "4358172", "title": "Letter: Imipramine and enuresis.", "content": "Letter: Imipramine and enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358172"}
{"pmid": "4358173", "title": "Phenotypic mixing of vesicular stomatitis virus with HVJ (Sendai virus).", "content": "Phenotypic mixing of vesicular stomatitis virus with HVJ (Sendai virus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358173"}
{"pmid": "4358175", "title": "Radiological experience with nasopharyngeal masses.", "content": "Radiological experience with nasopharyngeal masses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358175"}
{"pmid": "4358176", "title": "Effect of exogenous oestrogens on minor psychiatric symptoms in postmenopausal women.", "content": "Effect of exogenous oestrogens on minor psychiatric symptoms in postmenopausal women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358176"}
{"pmid": "4358183", "title": "Mannosidosis: clinical, fine-structural and biochemical findings in three cases.", "content": "Mannosidosis: clinical, fine-structural and biochemical findings in three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358183"}
{"pmid": "4358184", "title": "Renal function in long-term survivors after treatment for nephroblastoma.", "content": "Renal function in long-term survivors after treatment for nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358184"}
{"pmid": "4358185", "title": "Comparative measurements of enzyme activities and 2,3-diphosphoglycerate in the erythrocytes of newborns with transitory hyperbilirubinaemia.", "content": "Comparative measurements of enzyme activities and 2,3-diphosphoglycerate in the erythrocytes of newborns with transitory hyperbilirubinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358185"}
{"pmid": "4358186", "title": "Adrenal glucocorticoid function in acute viral infections in children.", "content": "Adrenal glucocorticoid function in acute viral infections in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358186"}
{"pmid": "4358189", "title": "Cyclic GMP and gastric acid secretion.", "content": "Cyclic GMP and gastric acid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358189"}
{"pmid": "4358191", "title": "Comprehensive training in forensic psychiatry.", "content": "Comprehensive training in forensic psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358191"}
{"pmid": "4358190", "title": "A guide for drug use in depressive disorders.", "content": "A guide for drug use in depressive disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358190"}
{"pmid": "4358192", "title": "Determination of sedimentation coefficients of subcellular particles of rat liver homogenates. A theoretical and experimental approach.", "content": "Determination of sedimentation coefficients of subcellular particles of rat liver homogenates. A theoretical and experimental approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358192"}
{"pmid": "4358194", "title": "Orthophosphate analysis by the Fiske-SubbaRow method and interference by adenosine phosphates and pyrophosphate at variable acid pH.", "content": "Orthophosphate analysis by the Fiske-SubbaRow method and interference by adenosine phosphates and pyrophosphate at variable acid pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358194"}
{"pmid": "4358193", "title": "Adenosine 3',5' cyclic monophosphate assay at 10-15 mole level.", "content": "Adenosine 3',5' cyclic monophosphate assay at 10-15 mole level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358193"}
{"pmid": "4358196", "title": "Clinical observations on response to nasal occlusion in infancy.", "content": "Clinical observations on response to nasal occlusion in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358196"}
{"pmid": "4358195", "title": "Determination of 25-hydroxycholecalciferol by combined thin layer and gas chromatography.", "content": "Determination of 25-hydroxycholecalciferol by combined thin layer and gas chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358195"}
{"pmid": "4358199", "title": "Genetic determinants of aminoglycoside resistance in strains of Mycobacterium tuberculosis.", "content": "Genetic determinants of aminoglycoside resistance in strains of Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358199"}
{"pmid": "4358201", "title": "Cellophane perinephritis hypertension and its reversal in rabbits. Effect on plasma renin, renin substrate, and renal mass.", "content": "Cellophane perinephritis hypertension and its reversal in rabbits. Effect on plasma renin, renin substrate, and renal mass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358201"}
{"pmid": "4358188", "title": "Interrelationship between bacterial histidine decarboxylase activity and concentration of histidine and pyridoxal-5'-phosphate.", "content": "Interrelationship between bacterial histidine decarboxylase activity and concentration of histidine and pyridoxal-5'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358188"}
{"pmid": "4358187", "title": "Investigations on the effects of diethazine on neuromuscular transmission in the rat.", "content": "Investigations on the effects of diethazine on neuromuscular transmission in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358187"}
{"pmid": "4358203", "title": "Glutamine phosphoribosylpyrophosphate amidotransferase.", "content": "Glutamine phosphoribosylpyrophosphate amidotransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358203"}
{"pmid": "4358202", "title": "Adrenergic control of the peripheral circulation in cardiomyopathic hamsters with heart failure.", "content": "Adrenergic control of the peripheral circulation in cardiomyopathic hamsters with heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358202"}
{"pmid": "4358204", "title": "Protein kinases.", "content": "Protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358204"}
{"pmid": "4358205", "title": "The effect of ACTH and cortisone on gastric acid mucosubstances in rats.", "content": "The effect of ACTH and cortisone on gastric acid mucosubstances in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358205"}
{"pmid": "4358207", "title": "The effects of delta8-THC on the EEG, reticular multiple unit activity and sleep of cats.", "content": "The effects of delta8-THC on the EEG, reticular multiple unit activity and sleep of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358207"}
{"pmid": "4358218", "title": "Analytical studies on ergot alkaloids and their derivatives. I. Separation of ergot alkaloids of the ergotoxine and ergotamine groups by thin-layer chromatography.", "content": "Analytical studies on ergot alkaloids and their derivatives. I. Separation of ergot alkaloids of the ergotoxine and ergotamine groups by thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358218"}
{"pmid": "4358219", "title": "Thin-layer chromatographic behaviour of the acetates of some polyfunctional diterpene alcohols of toxicological interest.", "content": "Thin-layer chromatographic behaviour of the acetates of some polyfunctional diterpene alcohols of toxicological interest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358219"}
{"pmid": "4358222", "title": "Synthesis and enzymic studies of 5-aminoimidazole and N-1-and N6-substituted adenine ribonucleoside cyclic 3',5'-phosphates prepared from adenosine cyclic 3',5'-phosphate.", "content": "Synthesis and enzymic studies of 5-aminoimidazole and N-1-and N6-substituted adenine ribonucleoside cyclic 3',5'-phosphates prepared from adenosine cyclic 3',5'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358222"}
{"pmid": "4358223", "title": "Lipolytic activity of Met-Arg-His-Phe-Arg-Trp-Gly, a synthetic analog of the ACTH (4-10) core sequence.", "content": "Lipolytic activity of Met-Arg-His-Phe-Arg-Trp-Gly, a synthetic analog of the ACTH (4-10) core sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358223"}
{"pmid": "4358225", "title": "Nucleic acid and polyamine synthesis in the rat during short-term protein deficiency: responsiveness of the liver to partial hepatectomy.", "content": "Nucleic acid and polyamine synthesis in the rat during short-term protein deficiency: responsiveness of the liver to partial hepatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358225"}
{"pmid": "4358226", "title": "Nucleic acid and polyamine synthesis in the rat during short-term protein deficiency: responsiveness of the bone marrow and liver to blood loss.", "content": "Nucleic acid and polyamine synthesis in the rat during short-term protein deficiency: responsiveness of the bone marrow and liver to blood loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358226"}
{"pmid": "4358224", "title": "Potential antidiabetic agents. Pyrazolo(3,4-b)pyridines.", "content": "Potential antidiabetic agents. Pyrazolo(3,4-b)pyridines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358224"}
{"pmid": "4358228", "title": "Letter: Minimal pressure neuropathy.", "content": "Letter: Minimal pressure neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358228"}
{"pmid": "4358227", "title": "Changes in serum pre-beta-lipoprotein following the feeding of sucrose. A preliminary trial in physically active and inactive young male students.", "content": "Changes in serum pre-beta-lipoprotein following the feeding of sucrose. A preliminary trial in physically active and inactive young male students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358227"}
{"pmid": "4358229", "title": "Alpha-thalassaemia in an Australian family.", "content": "Alpha-thalassaemia in an Australian family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358229"}
{"pmid": "4358230", "title": "Wilms' tumour: increasing hopes for survival.", "content": "Wilms' tumour: increasing hopes for survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358230"}
{"pmid": "4358236", "title": "Transfemoral catheter embolization: a method of treatment of glomus jugulare tumors.", "content": "Transfemoral catheter embolization: a method of treatment of glomus jugulare tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358236"}
{"pmid": "4358238", "title": "Viremia during parainfluenza type 3 virus infection of hamsters.", "content": "Viremia during parainfluenza type 3 virus infection of hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358238"}
{"pmid": "4358239", "title": "Further observations on the attachment of carbohydrate to lipoproteins by rat liver Golgi membranes.", "content": "Further observations on the attachment of carbohydrate to lipoproteins by rat liver Golgi membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358239"}
{"pmid": "4358240", "title": "Antagonism of morphine analgesia by adenine, adenosine, and adenine nucleotides.", "content": "Antagonism of morphine analgesia by adenine, adenosine, and adenine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358240"}
{"pmid": "4358234", "title": "Changes in phospholipid composition of Micrococcus lysodeikticus during growth.", "content": "Changes in phospholipid composition of Micrococcus lysodeikticus during growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358234"}
{"pmid": "4358242", "title": "The calcium-independent stimulation of thymic lymphoblast DNA synthesis by low cyclic GMP concentrations.", "content": "The calcium-independent stimulation of thymic lymphoblast DNA synthesis by low cyclic GMP concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358242"}
{"pmid": "4358241", "title": "Enancement of uptake of Simian virus 40 by nuclei of permissive cells.", "content": "Enancement of uptake of Simian virus 40 by nuclei of permissive cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358241"}
{"pmid": "4358243", "title": "Hepatis B virus antigen development in cultured human hepatocytes.", "content": "Hepatis B virus antigen development in cultured human hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358243"}
{"pmid": "4358244", "title": "Simplified method for isolation of cytomegalovirus and demonstration of frequent viremia in renal transplant patients.", "content": "Simplified method for isolation of cytomegalovirus and demonstration of frequent viremia in renal transplant patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358244"}
{"pmid": "4358232", "title": "Studies on the mode of action of dibromopropamidine.", "content": "Studies on the mode of action of dibromopropamidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358232"}
{"pmid": "4358245", "title": "The antitumor effect of interferon in lymphocyte- and macrophage-depressed mice.", "content": "The antitumor effect of interferon in lymphocyte- and macrophage-depressed mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358245"}
{"pmid": "4358246", "title": "Sucrose feeding in man. Effects of substrate incorporation into hepatic triglycerides and phosphoglycerides in vitro and on removal of intravenous fat in patients with hyperlipoproteinemia.", "content": "Sucrose feeding in man. Effects of substrate incorporation into hepatic triglycerides and phosphoglycerides in vitro and on removal of intravenous fat in patients with hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358246"}
{"pmid": "4358247", "title": "A simple automates fluorometric method for the determination of 2,3-diphosphoglycerate in blood.", "content": "A simple automates fluorometric method for the determination of 2,3-diphosphoglycerate in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358247"}
{"pmid": "4358233", "title": "Glycolytic enzyme activity of cells infected with adenovirus types 5 and 12.", "content": "Glycolytic enzyme activity of cells infected with adenovirus types 5 and 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358233"}
{"pmid": "4358248", "title": "Ectopic adrenocorticotropin syndrome with prostatic carcinoma.", "content": "Ectopic adrenocorticotropin syndrome with prostatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358248"}
{"pmid": "4358254", "title": "Molecular forms of glucose-6-phosphate dehydrogenase in liver diseases.", "content": "Molecular forms of glucose-6-phosphate dehydrogenase in liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358254"}
{"pmid": "4358255", "title": "Hepatic and adrenocortical function during cyclophosphamide stoss therapy.", "content": "Hepatic and adrenocortical function during cyclophosphamide stoss therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358255"}
{"pmid": "4358256", "title": "Hidroadenoma of the vulva.", "content": "Hidroadenoma of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358256"}
{"pmid": "4358257", "title": "Virion polypeptides and structure of SV40.", "content": "Virion polypeptides and structure of SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358257"}
{"pmid": "4358253", "title": "The influence of exogenous substrates on the breakdown of alcohol.", "content": "The influence of exogenous substrates on the breakdown of alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358253"}
{"pmid": "4358259", "title": "Production of equine infectious anemia antigen in a persistently infected cell line.", "content": "Production of equine infectious anemia antigen in a persistently infected cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358259"}
{"pmid": "4358258", "title": "Preparation of equine infectious anemia virus antigen for immunodiffusion test.", "content": "Preparation of equine infectious anemia virus antigen for immunodiffusion test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358258"}
{"pmid": "4358260", "title": "Multiple immobilized enzyme reactors: determination of pyruvate and phosphoenolpyruvate concentrations using immobilized lactate dehydrogenase and pyruvate kinase.", "content": "Multiple immobilized enzyme reactors: determination of pyruvate and phosphoenolpyruvate concentrations using immobilized lactate dehydrogenase and pyruvate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358260"}
{"pmid": "4358262", "title": "Structural characteristics of hydrated glycerol-and sphingo-lipids. A spin label study.", "content": "Structural characteristics of hydrated glycerol-and sphingo-lipids. A spin label study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358262"}
{"pmid": "4358263", "title": "Electrophoretic studies on three variants of Mengo encephalomyelitis virus.", "content": "Electrophoretic studies on three variants of Mengo encephalomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358263"}
{"pmid": "4358264", "title": "Synthesis and acid hydrolysis of monophosphate and pyrophosphate esters of phytanol and phytol.", "content": "Synthesis and acid hydrolysis of monophosphate and pyrophosphate esters of phytanol and phytol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358264"}
{"pmid": "4358265", "title": "Determination of bone age and recording of minor skeletal hand anomalies in normal children.", "content": "Determination of bone age and recording of minor skeletal hand anomalies in normal children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358265"}
{"pmid": "4358268", "title": "Susceptibility of herpesviruses to three nucleoside analogues and their combinations and enhancement of the antiviral effect of acid pH.", "content": "Susceptibility of herpesviruses to three nucleoside analogues and their combinations and enhancement of the antiviral effect of acid pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358268"}
{"pmid": "4358269", "title": "Ionic dependence of adrenal steroidogenesis and ACTH-induced changes in the membrane potential of adrenocortical cells.", "content": "Ionic dependence of adrenal steroidogenesis and ACTH-induced changes in the membrane potential of adrenocortical cells. 1. The effects of changes of ionic environment upon corticosteroid production by rabbit adrenal glands have been investigated in vitro using a superfusion technique and on-line steroid analysis by an automated fluorescence method. In some experiments micro-electrode recordings of adrenocortical transmembrane potentials were made concomitantly with measurement of steroid output.2. Adrenocorticotrophic hormone (ACTH), 10 m-u./ml., induced a sevenfold increase in corticosteroid production rate in normal Krebs solution.3. The steroidogenic response to ACTH was not impaired after omission of [K](o) for 1 hr but was inhibited following exposure to K(+)-free medium for 3 hr. Increase of [K](o) tenfold to 47 mM increased the basal but not the ACTH-stimulated output of corticosteroid whereas raising [K](o) twentyfold to 94 mM enhanced both the basal and ACTH-stimulated steroid production rate. In K(+)-free solution the adrenocortical cells hyperpolarized from - 67 to - 86 mV; subsequently on addition of ACTH they depolarized. Reintroduction of K(+) restored the membrane potential.4. Omission of Ca(2+) partially depolarized the cells but only affected the steroidogenic response to ACTH in the presence of EDTA. A threefold increase of [Ca](o), to 7.68 mM, had no effect on either membrane potentials or steroid formation, but increasing [Ca](o) tenfold to 25.6 mM partially blocked ACTH action. Increasing [Mg](o) twentyfold to 22.6 mM had little effect on ACTH-stimulated corticosteroid output and Sr 2.56 mM, in substitution for Ca(2+), supported ACTH action, but La, 0.25 mM, completely blocked the steroidogenic effect of ACTH.5. Replacement of NaCl, 118 mM by choline chloride, 118 mM, was without effect on ACTH-induced steroidogenesis, whereas LiCl, 118 mM, reduced it by 50%. NaF, 1 and 10 mM, inhibited ACTH-induced steroidogenesis by approximately 60%.6. Nupercaine, 10(-4)M, inhibited the steroid response to ACTH with no effect upon membrane potentials: increasing the nupercaine concentration to 10(-3)M inhibited the steroid response and depolarized the cells. Ouabain, 10(-5)M, induced complete depolarization and suppression of the steroidogenic response to ACTH.7. Action-potential-like changes in membrane potential appeared in cells exposed to ACTH in a K(+)-free medium. The amplitude of the action potentials ranged from 10 to 60 mV according to cell, with a frequency up to 36/min; the frequency tended to increase with time. Tetrodotoxin, 10(-6) g/ml., did not inhibit ACTH-induced action potentials in K(+)-free medium.8. These observations are discussed in relation to the ionic requirements for the steroidogenic action of ACTH. The results further emphasize the dissociation of membrane polarization and the secretion of steroid. The mechanism of output of steroid hormone from the adrenocortical cell may thus differ fundamentally from the secretory mechanisms in other, particle-storing cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358269"}
{"pmid": "4358271", "title": "Relaxing action of synthetic antispasmodics on the intestinal smooth muscle of guinea pig.", "content": "Relaxing action of synthetic antispasmodics on the intestinal smooth muscle of guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358271"}
{"pmid": "4358270", "title": "Effects of cyclic 3',5'-AMP and related compounds on catecholamine-induced contraction of isolated guinea-pig vas deferens.", "content": "Effects of cyclic 3',5'-AMP and related compounds on catecholamine-induced contraction of isolated guinea-pig vas deferens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358270"}
{"pmid": "4358273", "title": "Metabolic pathways involved in the oxidation of isopropanol into acetone by the intact rat.", "content": "Metabolic pathways involved in the oxidation of isopropanol into acetone by the intact rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358273"}
{"pmid": "4358272", "title": "Possibilities for drug development based on the cyclic AMP system.", "content": "Possibilities for drug development based on the cyclic AMP system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358272"}
{"pmid": "4358280", "title": "Hormonal control of bone cell function.", "content": "Hormonal control of bone cell function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358280"}
{"pmid": "4358281", "title": "Physiological significance of the vitamin D-dependent calcium-binding protein.", "content": "Physiological significance of the vitamin D-dependent calcium-binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358281"}
{"pmid": "4358284", "title": "Electron microscopic-immunocytochemical localization of adrenocorticotropin and melanocyte stimulating hormone in the pars intermedia cells of rats and mice.", "content": "Electron microscopic-immunocytochemical localization of adrenocorticotropin and melanocyte stimulating hormone in the pars intermedia cells of rats and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358284"}
{"pmid": "4358286", "title": "Light and electron microscopy of the early response of Escherichia coli to a 6beta-amidinopenicillanic acid (FL 1060).", "content": "Light and electron microscopy of the early response of Escherichia coli to a 6beta-amidinopenicillanic acid (FL 1060).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358286"}
{"pmid": "4358288", "title": "Microphotometry for determining the reaction rate of O2 and CO with red blood cells in the chorioallantoic capillary.", "content": "Microphotometry for determining the reaction rate of O2 and CO with red blood cells in the chorioallantoic capillary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358288"}
{"pmid": "4358287", "title": "Disintegration of single cells in suspension. Isolation of rabbit polymorphonuclear leucocyte granules.", "content": "Disintegration of single cells in suspension. Isolation of rabbit polymorphonuclear leucocyte granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358287"}
{"pmid": "4358289", "title": "The nephelometric and membrane filtration technique applied to serum lipoprotein investigation.", "content": "The nephelometric and membrane filtration technique applied to serum lipoprotein investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358289"}
{"pmid": "4358291", "title": "Ultracentrifugation of human lipoproteins.", "content": "Ultracentrifugation of human lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358291"}
{"pmid": "4358290", "title": "Biological significance of serum lipoproteins.", "content": "Biological significance of serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358290"}
{"pmid": "4358292", "title": "Origin and fate of lipoproteins.", "content": "Origin and fate of lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358292"}
{"pmid": "4358293", "title": "The metabolism of LDL.", "content": "The metabolism of LDL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358293"}
{"pmid": "4358294", "title": "The intravenous fat tolerance test with intralipid in various types of hyperlipidaemias and comparison between metabolism of intralipid and VLDL.", "content": "The intravenous fat tolerance test with intralipid in various types of hyperlipidaemias and comparison between metabolism of intralipid and VLDL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358294"}
{"pmid": "4358296", "title": "The effects of catecholamines on isolated perfused coronary arteries in the dog.", "content": "The effects of catecholamines on isolated perfused coronary arteries in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358296"}
{"pmid": "4358295", "title": "The biogenesis and metabolism of steroids in the human placenta of 9--14 weeks in vitro.", "content": "The biogenesis and metabolism of steroids in the human placenta of 9--14 weeks in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358295"}
{"pmid": "4358297", "title": "A study of some bradykinin potentiating peptides derived from plasma proteins.", "content": "A study of some bradykinin potentiating peptides derived from plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358297"}
{"pmid": "4358298", "title": "The pharmacology of dibenzofuran and terphenyl derivatives of DMAE and hemicholinium-3.", "content": "The pharmacology of dibenzofuran and terphenyl derivatives of DMAE and hemicholinium-3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358298"}
{"pmid": "4358302", "title": "Macrophage activation in mice infected with ectromelia or lymphocytic choriomeningitis viruses.", "content": "Macrophage activation in mice infected with ectromelia or lymphocytic choriomeningitis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358302"}
{"pmid": "4358301", "title": "Fine structure of phagocytic cells in the chiton, Liolophura gaimardi.", "content": "Fine structure of phagocytic cells in the chiton, Liolophura gaimardi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358301"}
{"pmid": "4358303", "title": "Replication of a cell-culture-modified infectious laryngotracheitis virus in experimentally infected chickens.", "content": "Replication of a cell-culture-modified infectious laryngotracheitis virus in experimentally infected chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358303"}
{"pmid": "4358305", "title": "Protection of chickens against Marek's disease virus JM-V strain with statolon and exogenous interferon.", "content": "Protection of chickens against Marek's disease virus JM-V strain with statolon and exogenous interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358305"}
{"pmid": "4358304", "title": "An avian adenovirus associated with respiratory disease.", "content": "An avian adenovirus associated with respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358304"}
{"pmid": "4358306", "title": "Chronologic study of the T-virus in chicks. I. Development of lesions.", "content": "Chronologic study of the T-virus in chicks. I. Development of lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358306"}
{"pmid": "4358312", "title": "The use of silica gel for human calcitonin isolation in some thyroid diseases.", "content": "The use of silica gel for human calcitonin isolation in some thyroid diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358312"}
{"pmid": "4358313", "title": "The effect of cyclazocine on the cardiovascular responses to pressor and depressor amines in the rat.", "content": "The effect of cyclazocine on the cardiovascular responses to pressor and depressor amines in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358313"}
{"pmid": "4358314", "title": "Serum and tissue dopamine-beta-hydroxylase activity in hypophysectomized rats.", "content": "Serum and tissue dopamine-beta-hydroxylase activity in hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358314"}
{"pmid": "4358315", "title": "Dictyostelium discoideum aggregation fields as excitable media.", "content": "Dictyostelium discoideum aggregation fields as excitable media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358315"}
{"pmid": "4358307", "title": "Chronologic study of the T-virus in chicks. II. Development of hematologic changes.", "content": "Chronologic study of the T-virus in chicks. II. Development of hematologic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358307"}
{"pmid": "4358308", "title": "Effect of social stress and steroids on antibody production.", "content": "Effect of social stress and steroids on antibody production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358308"}
{"pmid": "4358331", "title": "The effect of hyperactivity on synaptic transmission. Experiments in Blatta orientalis.", "content": "The effect of hyperactivity on synaptic transmission. Experiments in Blatta orientalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358331"}
{"pmid": "4358332", "title": "Adenosine metabolism: properties of dog heart microsomal 5'-nucleotidase.", "content": "Adenosine metabolism: properties of dog heart microsomal 5'-nucleotidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358332"}
{"pmid": "4358333", "title": "Viral isolation rates during summer from children with acute upper respiratory tract disease and healthy children.", "content": "Viral isolation rates during summer from children with acute upper respiratory tract disease and healthy children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358333"}
{"pmid": "4358334", "title": "Outbreak of a nosocomial infection with a strain of Proteus rettgeri resistant to many antimicrobials.", "content": "Outbreak of a nosocomial infection with a strain of Proteus rettgeri resistant to many antimicrobials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358334"}
{"pmid": "4358336", "title": "Recovery from severe cytomegalovirus pneumonia in a renal transplant patient.", "content": "Recovery from severe cytomegalovirus pneumonia in a renal transplant patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358336"}
{"pmid": "4358335", "title": "Massive intrapulmonary venoarterial shunting in alveolar cell carcinoma. A case report.", "content": "Massive intrapulmonary venoarterial shunting in alveolar cell carcinoma. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358335"}
{"pmid": "4358337", "title": "Guidelines for work for patients with tuberculosis.", "content": "Guidelines for work for patients with tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358337"}
{"pmid": "4358338", "title": "Effects of 2-N-(p-chlorobenzoyl)-N-(2-hydroxyethyl)aminomethyl-3-methyl-norbornane on ganglionic transmission and response to acetylcholine and pilocarpine.", "content": "Effects of 2-N-(p-chlorobenzoyl)-N-(2-hydroxyethyl)aminomethyl-3-methyl-norbornane on ganglionic transmission and response to acetylcholine and pilocarpine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358338"}
{"pmid": "4358339", "title": "Effects of essential phospholipids (EPL) on experimental cobalt-induced cardiomyopathy.", "content": "Effects of essential phospholipids (EPL) on experimental cobalt-induced cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358339"}
{"pmid": "4358342", "title": "The synergistic action of antifertility compounds in the male rat.", "content": "The synergistic action of antifertility compounds in the male rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358342"}
{"pmid": "4358343", "title": "Aflatoxin inhibition of rat liver mitochondria.", "content": "Aflatoxin inhibition of rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358343"}
{"pmid": "4358344", "title": "ACTH, glucagon and gastrin production by a pancreatic islet cell carcinoma and its treatment.", "content": "ACTH, glucagon and gastrin production by a pancreatic islet cell carcinoma and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358344"}
{"pmid": "4358345", "title": "Interaction between secretion of the gonadotrophins, prolactin, growth hormone, thyrotrophin and corticosteroids in man: the effects of LH FSH-RH, TRH and hypoglycaemia alone and in combination.", "content": "Interaction between secretion of the gonadotrophins, prolactin, growth hormone, thyrotrophin and corticosteroids in man: the effects of LH FSH-RH, TRH and hypoglycaemia alone and in combination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358345"}
{"pmid": "4358346", "title": "An improved isolation method and new composition data for Forssman hapten from sheep erythrocytes.", "content": "An improved isolation method and new composition data for Forssman hapten from sheep erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358346"}
{"pmid": "4358347", "title": "Decreased vasoconstrictor response to angiotensin II in the presence of vascular stenosis.", "content": "Decreased vasoconstrictor response to angiotensin II in the presence of vascular stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358347"}
{"pmid": "4358348", "title": "The inhibition by ouabain of phospholipid turnover in the myocardium of the rabbit.", "content": "The inhibition by ouabain of phospholipid turnover in the myocardium of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358348"}
{"pmid": "4358349", "title": "Protein fractions from mouse salivary glands affecting epithelial cells in organ culture.", "content": "Protein fractions from mouse salivary glands affecting epithelial cells in organ culture. 1. Extracts of male mouse submaxillary gland have been fractionated on G 150 Sephadex and DEAE cellulose.2. A number of the protein fractions obtained appear to cause proliferation of epithelial cells in organ cultures of rat tissues.3. All fractions active in organ culture possess proteolytic enzyme activity.4. The proteolytic enzymes trypsin, pronase and collagenase produce epithelial disorganization in organ culture.5. The organ culture effect is reduced in the presence of proteolytic enzyme inhibitors and abolished by pretreatment of proteins with diisopropylfluorophosphonate.6. The presence of mitotic inhibitors does not reduce the organ culture effect.7. The effect is not associated with an increase in the DNA content of tissue explants.8. No evidence has been found for the existence, in mouse salivary glands, of a specific growth factor acting on epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358349"}
{"pmid": "4358350", "title": "Proceedings: Excitatory and inhibitory monosynaptic actions mediated by a serotonin containing neurone in Aplysia californica.", "content": "Proceedings: Excitatory and inhibitory monosynaptic actions mediated by a serotonin containing neurone in Aplysia californica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358350"}
{"pmid": "4358351", "title": "The effect of repetitive stimulation on facilitation of transmitter release at the frog neuromuscular junction.", "content": "The effect of repetitive stimulation on facilitation of transmitter release at the frog neuromuscular junction. 1. End-plate potentials (e.p.p.s) were recorded from frog neuromuscular junctions blocked with high Mg and/or low Ca to characterize the processes underlying increased transmitter release during repetitive stimulation.2. There was a progressive increase in the amplitude of successive e.p.p.s during repetitive stimulation. Increasing the frequency or duration of stimulation increased this facilitation of e.p.p. amplitudes. Facilitation is defined as the fractional increase in amplitude of a test e.p.p. over a control.3. By assuming that each impulse in a train contributes an identical increment of facilitation that sums linearly with the facilitation contributed by the previous impulses, estimates of the facilitation contributed by a single impulse, f(t), were made from the incremental increase in e.p.p. amplitudes during repetitive stimulation. The average value of f(t) contributed by the first impulse in the train during stimulation at 20/sec is given by f(t) = 0.8 e(-t/50) + 0.12 e (-t/300) + 0.025 e(-t/3000),where t is in msec. The first two terms in this equation were independent of the stimulation rate used to determine f(t) while the coefficient of the third term was a function of the stimulation rate, decreasing 2 to 3 times when the stimulation rate was decreased from 20/sec to 1/sec.4. This linear facilitation model predicted growth of e.p.p. amplitudes during the first several hundred msec of repetitive stimulation. Thereafter, e.p.p. amplitudes were typically facilitated more than predicted by the linear model.5. Several new methods are presented which can be used to obtain estimates of the magnitude and time course of facilitation contributed by specific impulses during repetitive stimulation.6. It is found that the value of short-term f(t) in the tested range of 25-300 msec progressively increases during repetitive stimulation while its time course of decay remains unchanged. After 9 sec of stimulation at 20/sec, the short-term f(t) increased to 1.4 times control.7. The increase in short-term f(t) was independent of whether it was determined from a step increase or decrease in total facilitation, excluding the possibility that the observed increase in short-term f(t) resulted from a change in the rate of decay of facilitation.8. It is suggested with supporting data from the following paper (Magleby, 1973) that each impulse contributes two types of facilitation that are responsible for the growth of e.p.p.s during repetitive stimulation: a short-term facilitation with linear summation properties described by the first two terms in the expression in paragraph 3 and a long-term cumulative facilitation approximated by the third term. The long-term facilitation is expressed as an increase in both the short-term facilitation and in the base level of transmitter release. The relative contribution of these two expressions of the long-term facilitation to the third term is a function of the stimulation rate and is given by the ratio of facilitation to the base level of transmitter release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358351"}
{"pmid": "4358353", "title": "Proceedings: Ultrastructural changes at the synapse associated with depression of synaptic transmission in rat superior cervical ganglion after injury of post-ganglionic axons.", "content": "Proceedings: Ultrastructural changes at the synapse associated with depression of synaptic transmission in rat superior cervical ganglion after injury of post-ganglionic axons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358353"}
{"pmid": "4358352", "title": "The effect of tetanic and post-tetanic potentiation on facilitation of transmitter release at the frog neuromuscular junction.", "content": "The effect of tetanic and post-tetanic potentiation on facilitation of transmitter release at the frog neuromuscular junction. 1. End-plate potentials (e.p.p.s) were recorded from frog neuromuscular junctions blocked with high Mg and/or low Ca.2. Estimates of f(t), the facilitation contributed by each impulse, were obtained during and following repetitive stimulation from the incremental change in e.p.p. amplitudes following step changes in the stimulation rate during the conditioning and testing trains.3. Estimates of f(t) increased during the conditioning stimulation and returned to control in the post-tetanic period. This increase in f(t) was proportional to the magnitude of tetanic or post-tetanic potentiation (PTP) present.4. These results are described by: [Formula: see text] where h(t)/h(c) is the e.p.p. amplitude at time t expressed in terms of the control, P(t) is potentiation, F(t) is facilitation and 1 is the base level of transmitter release. Thus, potentiation has a multiplicative (gain) effect on facilitation and the base level of transmitter release.5. PTP was present immediately following the conditioning train. However, if depression occurred during the conditioning train, PTP developed after a delay.6. It is suggested that facilitation and potentiation represent increases in two independent factors which act jointly to increase the probability of transmitter release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358352"}
{"pmid": "4358354", "title": "Proceedings: Increased drinking in dogs during congestive heart failure.", "content": "Proceedings: Increased drinking in dogs during congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358354"}
{"pmid": "4358355", "title": "Proceedings: The upper limit of 'autoregulation' of cerebral blood flow in the baboon.", "content": "Proceedings: The upper limit of 'autoregulation' of cerebral blood flow in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358355"}
{"pmid": "4358357", "title": "Proceedings: Periodicities in ventilation in new-born infants.", "content": "Proceedings: Periodicities in ventilation in new-born infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358357"}
{"pmid": "4358356", "title": "Proceedings: Presynaptic inhibition and the depressant actions of GABA and glycine in the feline cuneate nucleus: changes related to electrographic seizure activity.", "content": "Proceedings: Presynaptic inhibition and the depressant actions of GABA and glycine in the feline cuneate nucleus: changes related to electrographic seizure activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358356"}
{"pmid": "4358358", "title": "Proceedings: Renin and angiotensin II of extrarenal origin in the plasma of female rabbits.", "content": "Proceedings: Renin and angiotensin II of extrarenal origin in the plasma of female rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358358"}
{"pmid": "4358360", "title": "Optical diffraction on tilting series of paracrystalline intranuclear inclusions of dog liver parenchymal cells.", "content": "Optical diffraction on tilting series of paracrystalline intranuclear inclusions of dog liver parenchymal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358360"}
{"pmid": "4358359", "title": "Proceedings: Prostaglandin E1 synthesis by phagocytosing rabbit polymorphonuclear leucocytes: its inhibition by indomethacin and its role in chemotaxis.", "content": "Proceedings: Prostaglandin E1 synthesis by phagocytosing rabbit polymorphonuclear leucocytes: its inhibition by indomethacin and its role in chemotaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358359"}
{"pmid": "4358361", "title": "Fine structure of spermiogenesis in scorpions from the family Vejovidae.", "content": "Fine structure of spermiogenesis in scorpions from the family Vejovidae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358361"}
{"pmid": "4358362", "title": "Diagnosis of glycogen storage disease type I by serum immunodiffusion.", "content": "Diagnosis of glycogen storage disease type I by serum immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358362"}
{"pmid": "4358363", "title": "Carcinogenicity of inhaled plutonium-238 in the rat.", "content": "Carcinogenicity of inhaled plutonium-238 in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358363"}
{"pmid": "4358364", "title": "Functional interpretation of lymphography according to contrast medium persistence in the lymph nodes.", "content": "Functional interpretation of lymphography according to contrast medium persistence in the lymph nodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358364"}
{"pmid": "4358366", "title": "Organization of glycolysis: oscillatory and stationary control.", "content": "Organization of glycolysis: oscillatory and stationary control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358366"}
{"pmid": "4358365", "title": "Kinetics of the renin system. The basis for determination of the different components of the system.", "content": "Kinetics of the renin system. The basis for determination of the different components of the system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358365"}
{"pmid": "4358368", "title": "Regulation of gene expression by cyclic AMP in Escherichia coli.", "content": "Regulation of gene expression by cyclic AMP in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358368"}
{"pmid": "4358367", "title": "Mitochondrial-cytosolic interactions in cardiac tissue: role of the malate-aspartate cycle in the removal of glycolytic NADH from the cytosol.", "content": "Mitochondrial-cytosolic interactions in cardiac tissue: role of the malate-aspartate cycle in the removal of glycolytic NADH from the cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358367"}
{"pmid": "4358369", "title": "Rate control by insulin and its mechanism.", "content": "Rate control by insulin and its mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358369"}
{"pmid": "4358370", "title": "Enzyme conformation and control.", "content": "Enzyme conformation and control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358370"}
{"pmid": "4358372", "title": "Frequency of renal intraendothelial microtubular inclusions in kidney transplants. An electron microscopy study.", "content": "Frequency of renal intraendothelial microtubular inclusions in kidney transplants. An electron microscopy study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358372"}
{"pmid": "4358371", "title": "Search for BK and SV40 virus reactivation in renal transplant recipients.", "content": "Search for BK and SV40 virus reactivation in renal transplant recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358371"}
{"pmid": "4358373", "title": "Studies on the tumor target cell destruction by in vitro sensitized lymphocytes.", "content": "Studies on the tumor target cell destruction by in vitro sensitized lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358373"}
{"pmid": "4358376", "title": "Ultrastructure of experimental brain gliomas in mice.", "content": "Ultrastructure of experimental brain gliomas in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358376"}
{"pmid": "4358375", "title": "Immunobiology of genitourinary tumors.", "content": "Immunobiology of genitourinary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358375"}
{"pmid": "4358381", "title": "The cytopyge of Ciliata. II. Microphotographical documentation of the defecation in Prorodon teres.", "content": "The cytopyge of Ciliata. II. Microphotographical documentation of the defecation in Prorodon teres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358381"}
{"pmid": "4358380", "title": "A comparative study on the seed proteins of induced mutants of the pea.", "content": "A comparative study on the seed proteins of induced mutants of the pea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358380"}
{"pmid": "4358382", "title": "The cytopyge of Ciliata. 3. Microphotographical documentation of the defecation in Blepharisma ovata.", "content": "The cytopyge of Ciliata. 3. Microphotographical documentation of the defecation in Blepharisma ovata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358382"}
{"pmid": "4358384", "title": "Increased cellular reaction to damage caused by angiotensin in arterioles of normal recipient rats after transfer of lymphocytes from hypertensive rats.", "content": "Increased cellular reaction to damage caused by angiotensin in arterioles of normal recipient rats after transfer of lymphocytes from hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358384"}
{"pmid": "4358383", "title": "The effect of cyclic AMP on the erythropoiesis in mice(NMRI).", "content": "The effect of cyclic AMP on the erythropoiesis in mice(NMRI).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358383"}
{"pmid": "4358385", "title": "Cause of the prolonged pressor action of renin in nephrectomized rats. Elucidated by means of anti-angiotensin II and of angiotensin-inhibitor (1-sar-8-ala-angiotensin II).", "content": "Cause of the prolonged pressor action of renin in nephrectomized rats. Elucidated by means of anti-angiotensin II and of angiotensin-inhibitor (1-sar-8-ala-angiotensin II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358385"}
{"pmid": "4358386", "title": "Role of the renin-system in normo- and hypertension. Effect of angiotensin-inhibitor (1-sar-8-ala-angiotensin II) on the blood pressure of conscious or anaesthetized normal, nephrectomized and renal hypertensive rats.", "content": "Role of the renin-system in normo- and hypertension. Effect of angiotensin-inhibitor (1-sar-8-ala-angiotensin II) on the blood pressure of conscious or anaesthetized normal, nephrectomized and renal hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358386"}
{"pmid": "4358387", "title": "On the side-effects of contrast media for myelography. A histological examination of the spinal cord, nerve roots and meninges after experimental myelography with iodophendylate and methiodal.", "content": "On the side-effects of contrast media for myelography. A histological examination of the spinal cord, nerve roots and meninges after experimental myelography with iodophendylate and methiodal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358387"}
{"pmid": "4358388", "title": "Rapid marked increase in plasma renin in rats treated with inhibitors of the renin system. Effects of 1-sar-8-ala-angiotensin II and of a synthetic converting enzyme inhibitor (nonapeptide, SQ 20.881) on normal and adrenalectomized rats.", "content": "Rapid marked increase in plasma renin in rats treated with inhibitors of the renin system. Effects of 1-sar-8-ala-angiotensin II and of a synthetic converting enzyme inhibitor (nonapeptide, SQ 20.881) on normal and adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358388"}
{"pmid": "4358389", "title": "Experiences with depot neuroleptics in an after-care department.", "content": "Experiences with depot neuroleptics in an after-care department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358389"}
{"pmid": "4358390", "title": "Protein deprivation in primates. I. Nonpregnant adult rhesus monkeys.", "content": "Protein deprivation in primates. I. Nonpregnant adult rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358390"}
{"pmid": "4358392", "title": "Electron microscopic observations on human glioblastomas and astrocytomas maintained in organ culture systems.", "content": "Electron microscopic observations on human glioblastomas and astrocytomas maintained in organ culture systems. The fine structure of four glioblastomas and two cerebellar astrocytomas maintained in organ culture systems up to 137 days and 43 days, respectively, using either a three-dimensional sponge foam matrix technic or a Millipore filter platform technic, is described and compared. The cells of both tumor types showed increased astrocytic differentiation, characterized by a progressive increase in glial filaments associated with an increase in free ribosomes and granular endoplasmic reticulum. A progressive increase in basement membrane material, presumably originating from explanted endothelial cells or pericytes, was also found in both tumor types and was often associated with increased numbers of collagen fibrils. Astrocytic tumor cell processes frequently preserved their contact with this basement membrane material. Microvascular fenestrations or gaps in endothelial cells were not identified. These electron microscopic features appear to correspond to the early stages of perivascular sclerosis previously noted by light microscopy in gliomas maintained in organ culture systems and are presumably related to the progressive obliteration of the functional microvasculature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358392"}
{"pmid": "4358393", "title": "Salmonella typhimurium hisG46 (R-Utrecht): possible use in screening mutagens and carcinogens.", "content": "Salmonella typhimurium hisG46 (R-Utrecht): possible use in screening mutagens and carcinogens. Salmonella typhimurium LT2 hisG46 becomes a more sensitive strain for assaying mutagens and carcinogens when it carries the resistance transfer factor R-Utrecht.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358393"}
{"pmid": "4358391", "title": "Lipid metabolism and experimental atherosclerosis in baboons: influence of cholesterol-free, semi-synthetic diets.", "content": "Lipid metabolism and experimental atherosclerosis in baboons: influence of cholesterol-free, semi-synthetic diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358391"}
{"pmid": "4358394", "title": "Spiradenoma. Histochemical and electron microscopic study.", "content": "Spiradenoma. Histochemical and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358394"}
{"pmid": "4358395", "title": "Vitamin E treatment of epidermolysis bullosa. Changes in tissue collagenase levels.", "content": "Vitamin E treatment of epidermolysis bullosa. Changes in tissue collagenase levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358395"}
{"pmid": "4358396", "title": "Letter: Intertriginous xanthomas.", "content": "Letter: Intertriginous xanthomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358396"}
{"pmid": "4358397", "title": "A difference in the breakdown of phosphatidylinositol in normal and SV40 transformed mouse fibroblasts.", "content": "A difference in the breakdown of phosphatidylinositol in normal and SV40 transformed mouse fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358397"}
{"pmid": "4358398", "title": "Separation and comparison of primary structures of three formylmethionine tRNAs from E. coli K-12 MO.", "content": "Separation and comparison of primary structures of three formylmethionine tRNAs from E. coli K-12 MO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358398"}
{"pmid": "4358399", "title": "The valence of copper and the role of superoxide in the D-galactose oxidase catalyzed reaction.", "content": "The valence of copper and the role of superoxide in the D-galactose oxidase catalyzed reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358399"}
{"pmid": "4358400", "title": "Electron paramagnetic resonance studies of iron-sulfur centers in mitochondria prepared from three Morris hepatomas with different growth rates.", "content": "Electron paramagnetic resonance studies of iron-sulfur centers in mitochondria prepared from three Morris hepatomas with different growth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358400"}
{"pmid": "4358401", "title": "The effects of some cations and anions on spin labeled cytoplasmic membranes of Bacillus subtilis.", "content": "The effects of some cations and anions on spin labeled cytoplasmic membranes of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358401"}
{"pmid": "4358402", "title": "Cyclic changes in levels of cyclic AMP and cyclic GMP in frog myocardium during the cardiac cycle.", "content": "Cyclic changes in levels of cyclic AMP and cyclic GMP in frog myocardium during the cardiac cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358402"}
{"pmid": "4358403", "title": "Altered nuclear RNA transport associated with carcinogen intoxication in rats.", "content": "Altered nuclear RNA transport associated with carcinogen intoxication in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358403"}
{"pmid": "4358404", "title": "Adrenocorticotropic hormone and dibutryl adenosine cyclic monophosphate-mediated Ca2+ uptake by rat adrenal glands.", "content": "Adrenocorticotropic hormone and dibutryl adenosine cyclic monophosphate-mediated Ca2+ uptake by rat adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358404"}
{"pmid": "4358405", "title": "The effect of glucose ingestion on basal and induced enzyme levels in rat tissues.", "content": "The effect of glucose ingestion on basal and induced enzyme levels in rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358405"}
{"pmid": "4358406", "title": "The delta-aminolevulinic acid synthetase activity and the effect of exogenous delta-aminolevulinate on the synthesis of cytochrome c in the thoracic muscles of the tobacco horn worm during adult development.", "content": "The delta-aminolevulinic acid synthetase activity and the effect of exogenous delta-aminolevulinate on the synthesis of cytochrome c in the thoracic muscles of the tobacco horn worm during adult development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358406"}
{"pmid": "4358407", "title": "A bromine compound isolated from human cerebrospinal fluid.", "content": "A bromine compound isolated from human cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358407"}
{"pmid": "4358408", "title": "Variation of proteins, enzyme markers and gangliosides in myelin subfractions.", "content": "Variation of proteins, enzyme markers and gangliosides in myelin subfractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358408"}
{"pmid": "4358409", "title": "Effects of infusions of catecholamines, angiotensin, vasopressin and histamine on hepatic blood volume in the anaesthetized cat.", "content": "Effects of infusions of catecholamines, angiotensin, vasopressin and histamine on hepatic blood volume in the anaesthetized cat. 1. Hepatic volume was recorded by a plethysmographic technique in cats anaesthetized with pentobarbitone; the hepatic artery and portal vein remained intact. Dose-response curves were obtained for intravenous infusions of adrenaline, noradrenaline, angiotensin, vasopressin and histamine.2. Adrenaline and noradrenaline decreased hepatic blood volume and did not differ significantly in potency. Up to 40% of the hepatic blood volume was expelled by doses within the range secreted by the adrenal medullae.3. Isoprenaline, infused into the hepatic artery, had no significant effect on hepatic blood volume in doses which caused maximal vasodilatation of the hepatic arterial bed. Relaxation of hepatic capacitance vessels mediated by beta-adrenoceptors did not occur.4. Angiotensin infusions in doses previously shown to cause intestinal and splenic vasoconstriction, decreased hepatic blood volume and on a molar or microgramme basis, angiotensin was the most potent of the agents tested. Doses within the probable physiological range of endogenous production decreased hepatic blood volume by up to 20%. The responses were not significantly different when the hepatic nerves were intact or sectioned.5. Vasopressin infusions produced only small decreases in hepatic blood volume. Doses within the range secreted by the posterior pituitary which constrict the intestinal and splenic resistance vessels, did not decrease hepatic blood volume by more than 10%.6. Histamine produced no change in hepatic blood volume in doses which readily produce outflow block in dogs. Either the specific hepatic venous smooth muscle involved in outflow block is absent in the cat or it has no histamine receptors.7. After the rapid change in hepatic blood volume at the onset of the infusion, hepatic volume remained steady for the duration of each infusion. There was no evidence that these agents caused net transsinusoidal fluid movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358409"}
{"pmid": "4358411", "title": "Some aspects of the inhibition of the action of antidiuretic hormone by lithium ions in the rat kidney and bladder of the toad Bufo marinus.", "content": "Some aspects of the inhibition of the action of antidiuretic hormone by lithium ions in the rat kidney and bladder of the toad Bufo marinus. 1. The effect of intravenous infusions of various ions on the antidiuretic action of antidiuretic hormone has been studied in rats.2. Lithium (13 mmol/l.) reversibly inhibits the antidiuretic responses. Similar concentrations of potassium, rubidium, strontium, magnesium, choline and calcium do not. Lithium has a similar effect on the antidiuretic activity of oxytocin.3. The inhibition is not simply related to blood nor whole body lithium concentrations.4. Lithium (2 mmol/l.) in contact with the serosal surface also inhibits the transport of water facilitated by either 0.5 U/l. antidiuretic hormone or 1.1 mmol/l. cyclic adenosine monophosphate in the isolated toad bladder.5. Choline (2 mmol/l.) on the serosal surface also inhibits the transport of water facilitated by vasopressin in the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358411"}
{"pmid": "4358410", "title": "Selective inhibition of angiotensin pressor responses in the pithed rat by tetraethylthiuram disulphide (disulfiram) and sodium diethyldithiocarbamate (DDC).", "content": "Selective inhibition of angiotensin pressor responses in the pithed rat by tetraethylthiuram disulphide (disulfiram) and sodium diethyldithiocarbamate (DDC). 1. Pressor responses to sympathetic outflow stimulation, noradrenaline and angiotensin have been recorded in pithed rats.2. Disulfiram (50 mg/kg) and sodium diethyldithiocarbamate (DDC) (5-100 mg/kg) both caused an initial increase in the pressor response to all three procedures followed by a selective inhibition of the angiotensin responses.3. Penicillamine (1-100 mg/kg) and ascorbic acid (1-500 mg/kg) increased the pressor responses to all three procedures without any subsequent blocking action.4. Reserpine (5 mg/kg daily for 3 days) abolished responses to sympathetic outflow stimulation but did not impair angiotensin or noradrenaline responses.5. In reserpinized rats, the initial enhancement of angiotensin responses after disulfiram and sodium diethyldithiocarbamate was absent or reduced and the onset of the subsequent block was accelerated.6. Possible mechanisms for the angiotensin-blocking action of disulfiram and sodium diethyldithiocarbamate are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358410"}
{"pmid": "4358412", "title": "Proceedings: Alterations in the sleep-wakefulness cycle in rats after administration of (-)-LSD or BOL-148: a comparison with (+)-LSD.", "content": "Proceedings: Alterations in the sleep-wakefulness cycle in rats after administration of (-)-LSD or BOL-148: a comparison with (+)-LSD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358412"}
{"pmid": "4358413", "title": "Proceedings: Active factors in the venom duct of Conus californicus.", "content": "Proceedings: Active factors in the venom duct of Conus californicus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358413"}
{"pmid": "4358414", "title": "Proceedings: Concentrations of the oxime 2-hydroxyiminomethyl pyridinium methyl methane sulphonate (P2S) after intramuscular injections in humans.", "content": "Proceedings: Concentrations of the oxime 2-hydroxyiminomethyl pyridinium methyl methane sulphonate (P2S) after intramuscular injections in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358414"}
{"pmid": "4358416", "title": "Proceedings: New dialysis technique for the continuous measurement of the concentration of vasoactive hormones.", "content": "Proceedings: New dialysis technique for the continuous measurement of the concentration of vasoactive hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358416"}
{"pmid": "4358415", "title": "Proceedings: Tissue cyanide concentrations and cytochrome oxidase in experimental cyanide poisoning.", "content": "Proceedings: Tissue cyanide concentrations and cytochrome oxidase in experimental cyanide poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358415"}
{"pmid": "4358417", "title": "The modern ankle-foot orthoses (AFO's).", "content": "The modern ankle-foot orthoses (AFO's).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358417"}
{"pmid": "4358419", "title": "Human pancreatic islet tumor cells maintained in vitro.", "content": "Human pancreatic islet tumor cells maintained in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358419"}
{"pmid": "4358422", "title": "Inhibition of glucose-induced insulin secretion in trypsin-treated islets of Langerhans.", "content": "Inhibition of glucose-induced insulin secretion in trypsin-treated islets of Langerhans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358422"}
{"pmid": "4358423", "title": "Effect of diabetes and insulin on the rat heart adenyl cyclase, cyclic AMP phosphodiesterase and cyclic AMP.", "content": "Effect of diabetes and insulin on the rat heart adenyl cyclase, cyclic AMP phosphodiesterase and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358423"}
{"pmid": "4358424", "title": "Plasma ACTH in the adrenalectomized rat.", "content": "Plasma ACTH in the adrenalectomized rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358424"}
{"pmid": "4358425", "title": "Serum parathyroid hormone concentrations in vitamin D deficiency rickets of infancy: effects of intravenous calcium and vitamin D.", "content": "Serum parathyroid hormone concentrations in vitamin D deficiency rickets of infancy: effects of intravenous calcium and vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358425"}
{"pmid": "4358426", "title": "Melanotic progonoma of the brain.", "content": "Melanotic progonoma of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358426"}
{"pmid": "4358427", "title": "The histiocytic infiltrates of the skin.", "content": "The histiocytic infiltrates of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358427"}
{"pmid": "4358428", "title": "Postnatal cytomegalovirus hepatitis. An autopsy and liver biopsy study.", "content": "Postnatal cytomegalovirus hepatitis. An autopsy and liver biopsy study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358428"}
{"pmid": "4358429", "title": "Inhibition of cell growth in the G1 phase by adenosine 3', 5'-cyclic monophosphate.", "content": "Inhibition of cell growth in the G1 phase by adenosine 3', 5'-cyclic monophosphate. Incorporation of tritiated thymidine into acid-precipitable material was used to measure the rate of DNA synthesis in secondary cultures of human diploid fibroblasts. Confluent cultures of human diploid fibroblasts, which are synchronized in the G(1) phase due to contact inhibition, were released from growth inhibition either by the addition of fresh medium to the cultures or by trypsinization and replating at nonconfluent densities. Either treatment resulted in a synchronous wave of DNA synthesis beginning 10-15 h after treatment and peaking at 20-25 h. In confluent cultures stimulated by fresh medium, either the addition of 0.25 mM N(6), O(2)-dibutyryl-adenosine 3',5'-cyclic monophosphate (db-cAMP) to the medium in the interval 4-8 h after stimulation or the replacement of the fresh medium in that same 4 h interval with the depleted medium present on the cells for the 2 day period before stimulation delayed the synchronous onset of DNA synthesis in the cultures by about 4 h. In nonconfluent cultures freshly seeded from trypsinized confluent cultures, this same depleted medium obtained after a 2 day incubation of fresh medium on confluent cultures is shown to support the progress of the cells into S phase; however, the addition of 0.25 mM db-cAMP to the medium 3(1/2) h after replating still partially prevented the initiation of DNA synthesis in the cultures. The results are discussed in terms of the role of serum and cAMP in the control of cell growth in fibroblast cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358429"}
{"pmid": "4358418", "title": "Editorial: Role of the kidney in the metabolism of calciferol (vitamin D).", "content": "Editorial: Role of the kidney in the metabolism of calciferol (vitamin D).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358418"}
{"pmid": "4358430", "title": "Cytochemistry of Golgi fractions prepared from rat liver.", "content": "Cytochemistry of Golgi fractions prepared from rat liver. Cytochemical tests for several marker enzymes were applied to liver tissue and to the three Golgi fractions (GF(1), GF(2), GF(3)) separated by the procedure of Ehrenreich et al. from liver homogenates of alcohol-treated rats. 5'-Nucleotidase (AMPase) reaction product was found in all three fractions but in different locations: It occurred along the inside of the membrane of VLDL-filled vacuoles in GF(1) and GF(2), and along the outside of the cisternal membranes in GF(3). In the latter it was restricted to the dilated cisternal rims and was absent from the cisternal centers. The AMPase activity found in the fractions by biochemical assay is therefore indigenous to Golgi components and is not due to contamination by plasma membrane. Acid phosphatase (AcPase) reaction product was detected within lysosomal contaminants in GF(1) and within many VLDL-filled vacuoles in GF(1) and GF(2), indicating that AcPase activity is due not only to contaminating lysosomes, but also to enzyme indigenous to Golgi secretory vacuoles. G-6-Pase reaction product was present in GF(3) and within contaminating endoplasmic reticulum fragments, but not in other fractions. Thiamine pyrophosphatase (TPPase) was localized to some of the VLDL-filled vacuoles and cisternae in GF(1) and GF(2), and was not found in the cisternae in GF(3). The results demonstrate the usefulness of cytochemical methods in monitoring the fractionation procedure: They have (a) allowed a reliable identification of contaminants, (b) made possible a distinction between indigenous and contaminating activities, and (c) shown, primarily by the results of the TPPase test, that the procedure achieves a meaningful subfractionation of Golgi elements, with GF(1) and GF(3), representing primarily trans-Golgi elements from the secretory Golgi face, and GF(3) consisting largely of cis-Golgi components from the opposite face.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358430"}
{"pmid": "4358431", "title": "Adrenocorticotropin. 45. Synthesis and steroidogenic activity of (1-alanine)adrenocorticotropin-(1-20)-amide, (1-D-alanine)adrenocorticotropin-(1-20)-amide, and (1-14C)alanine)adrenocorticotropin-(1-20)-amide.", "content": "Adrenocorticotropin. 45. Synthesis and steroidogenic activity of (1-alanine)adrenocorticotropin-(1-20)-amide, (1-D-alanine)adrenocorticotropin-(1-20)-amide, and (1-14C)alanine)adrenocorticotropin-(1-20)-amide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358431"}
{"pmid": "4358432", "title": "Angiotensin-like and antagonistic activities of N-terminal modified (8-leucine)angiotensin II peptides.", "content": "Angiotensin-like and antagonistic activities of N-terminal modified (8-leucine)angiotensin II peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358432"}
{"pmid": "4358433", "title": "Synthesis and anti-deoxyribonucleic acid virus activity of certain 9-beta-D-arabinofuranosyl-2-substituted adenine derivatives.", "content": "Synthesis and anti-deoxyribonucleic acid virus activity of certain 9-beta-D-arabinofuranosyl-2-substituted adenine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358433"}
{"pmid": "4358434", "title": "Propagation of both parental mitochondrial DNAs in rat-human and mouse-human hybrid cells.", "content": "Propagation of both parental mitochondrial DNAs in rat-human and mouse-human hybrid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358434"}
{"pmid": "4358436", "title": "Angiotensin analogs: the influence of sarcosine substituted in position 1.", "content": "Angiotensin analogs: the influence of sarcosine substituted in position 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358436"}
{"pmid": "4358435", "title": "Inhibition of adrenergic vasoconstriction by quinidine.", "content": "Inhibition of adrenergic vasoconstriction by quinidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358435"}
{"pmid": "4358437", "title": "Renin release and ketamine-induced cardiovascular stimulation in the rat.", "content": "Renin release and ketamine-induced cardiovascular stimulation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358437"}
{"pmid": "4358438", "title": "Effect of certain halogenated hydrocarbon insecticides on cyclic adenosine 3',5'-monophosphate-3H formation by rat kidney cortex.", "content": "Effect of certain halogenated hydrocarbon insecticides on cyclic adenosine 3',5'-monophosphate-3H formation by rat kidney cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358438"}
{"pmid": "4358439", "title": "Lipid-protein and lipid-lipid interactions in cytochrome oxidase model membranes.", "content": "Lipid-protein and lipid-lipid interactions in cytochrome oxidase model membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358439"}
{"pmid": "4358440", "title": "The fluid state of lecithin bilayers.", "content": "The fluid state of lecithin bilayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358440"}
{"pmid": "4358441", "title": "Synaptic vesicles: structure of chromaffin granule membranes.", "content": "Synaptic vesicles: structure of chromaffin granule membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358441"}
{"pmid": "4358442", "title": "Rhodopsin-lipid interactions.", "content": "Rhodopsin-lipid interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358442"}
{"pmid": "4358444", "title": "Adenylate cyclase and cyclic AMP phosphodiesterase of normal and Rous sarcoma virus transformed chicken embryo fibroblasts.", "content": "Adenylate cyclase and cyclic AMP phosphodiesterase of normal and Rous sarcoma virus transformed chicken embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358444"}
{"pmid": "4358443", "title": "The effect of cyclic AMP on membrane permeability.", "content": "The effect of cyclic AMP on membrane permeability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358443"}
{"pmid": "4358445", "title": "Red cell aggregation by macromolecules: roles of surface adsorption and electrostatic repulsion.", "content": "Red cell aggregation by macromolecules: roles of surface adsorption and electrostatic repulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358445"}
{"pmid": "4358446", "title": "New developments in pharmacology of vitamin D.", "content": "New developments in pharmacology of vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358446"}
{"pmid": "4358448", "title": "Host defenses against viral disease.", "content": "Host defenses against viral disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358448"}
{"pmid": "4358447", "title": "Inapparent congenital cytomegalovirus infection with elevated cord IgM levels. Casual relation with auditory and mental deficiency.", "content": "Inapparent congenital cytomegalovirus infection with elevated cord IgM levels. Casual relation with auditory and mental deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358447"}
{"pmid": "4358450", "title": "The clinical value of the magnification technique in cerebral angiography.", "content": "The clinical value of the magnification technique in cerebral angiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358450"}
{"pmid": "4358449", "title": "Editorial: Subtle effects of perinatal infection.", "content": "Editorial: Subtle effects of perinatal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358449"}
{"pmid": "4358451", "title": "Vincristine therapy in malignant glioma recurrencies.", "content": "Vincristine therapy in malignant glioma recurrencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358451"}
{"pmid": "4358452", "title": "Increased activity of adenine phosphoribosyltransferase in erythrocytes of normal newborn infants.", "content": "Increased activity of adenine phosphoribosyltransferase in erythrocytes of normal newborn infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358452"}
{"pmid": "4358456", "title": "Antibodies to Epstein-Barr virus at the ages of 6 to 23 months in children with congenital heart disease.", "content": "Antibodies to Epstein-Barr virus at the ages of 6 to 23 months in children with congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358456"}
{"pmid": "4358455", "title": "Ethanol consumption and enzyme activities in Sinclair miniature pigs.", "content": "Ethanol consumption and enzyme activities in Sinclair miniature pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358455"}
{"pmid": "4358454", "title": "Marital group therapy in the treatment of alcoholism.", "content": "Marital group therapy in the treatment of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358454"}
{"pmid": "4358457", "title": "Serologic studies of infections in patients with hematologic malignancy.", "content": "Serologic studies of infections in patients with hematologic malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358457"}
{"pmid": "4358459", "title": "Inhibition by castration of aflatoxin-induced hepatoma in carbon tetrachloride-treated rats.", "content": "Inhibition by castration of aflatoxin-induced hepatoma in carbon tetrachloride-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358459"}
{"pmid": "4358458", "title": "Serotypes and antibiotic susceptibility of Escherichia coli in non-enteric infections of children.", "content": "Serotypes and antibiotic susceptibility of Escherichia coli in non-enteric infections of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358458"}
{"pmid": "4358460", "title": "The cardiotoxic effects of pressurized aerosol isoproterenol in the dog.", "content": "The cardiotoxic effects of pressurized aerosol isoproterenol in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358460"}
{"pmid": "4358466", "title": "The bone cell system: form and function.", "content": "The bone cell system: form and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358466"}
{"pmid": "4358463", "title": "Hepatoma--nature's model tumor. A review.", "content": "Hepatoma--nature's model tumor. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358463"}
{"pmid": "4358467", "title": "Tumor doubling time and survival of men with bronchogenic carcinoma.", "content": "Tumor doubling time and survival of men with bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358467"}
{"pmid": "4358469", "title": "Structural requirements for substrates and inhibitors of angiotensin I-converting enzyme in vivo and vitro.", "content": "Structural requirements for substrates and inhibitors of angiotensin I-converting enzyme in vivo and vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358469"}
{"pmid": "4358468", "title": "Fulminant lymphoma mimicking pneumocystis carinii pneumonia.", "content": "Fulminant lymphoma mimicking pneumocystis carinii pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358468"}
{"pmid": "4358470", "title": "Sensitization of the adrenal cortex to angiotensin II in sodium-deplete man.", "content": "Sensitization of the adrenal cortex to angiotensin II in sodium-deplete man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358470"}
{"pmid": "4358471", "title": "The pathophysiology of renin.", "content": "The pathophysiology of renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358471"}
{"pmid": "4358474", "title": "Hexachlorophene revisited.", "content": "Hexachlorophene revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358474"}
{"pmid": "4358473", "title": "Effects of neuroleptanesthesia on endocrine function in man.", "content": "Effects of neuroleptanesthesia on endocrine function in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358473"}
{"pmid": "4358475", "title": "The surgical management of axillary hyperhidrosis.", "content": "The surgical management of axillary hyperhidrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358475"}
{"pmid": "4358476", "title": "Sophisticated simplification for medical services.", "content": "Sophisticated simplification for medical services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358476"}
{"pmid": "4358478", "title": "Helen Brenton Pryor, M.D.--pediatrician. (1898-1972).", "content": "Helen Brenton Pryor, M.D.--pediatrician. (1898-1972).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358478"}
{"pmid": "4358479", "title": "Letter: Women to the rescue.", "content": "Letter: Women to the rescue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358479"}
{"pmid": "4358477", "title": "History of the library trust fund.", "content": "History of the library trust fund.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358477"}
{"pmid": "4358480", "title": "A study of hepatitis-associated antigen in hospital patients.", "content": "A study of hepatitis-associated antigen in hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358480"}
{"pmid": "4358481", "title": "Tumor rejection and immunotherapy studies with simian virus 40-induced tumors.", "content": "Tumor rejection and immunotherapy studies with simian virus 40-induced tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358481"}
{"pmid": "4358482", "title": "Pentose shunt enzyme activities in non-inflamed attached gingiva of dogs.", "content": "Pentose shunt enzyme activities in non-inflamed attached gingiva of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358482"}
{"pmid": "4358483", "title": "The lung--an endocrine organ?", "content": "The lung--an endocrine organ?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358483"}
{"pmid": "4358484", "title": "Diabetic foot.", "content": "Diabetic foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358484"}
{"pmid": "4358488", "title": "Persistent cloaca with no urethral, genital, or anal openings.", "content": "Persistent cloaca with no urethral, genital, or anal openings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358488"}
{"pmid": "4358489", "title": "Perinatal infections and epidemiology of anencephaly and spina bifida.", "content": "Perinatal infections and epidemiology of anencephaly and spina bifida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358489"}
{"pmid": "4358500", "title": "Skin hypersensitivity to parainfluenza-3 virus in cattle.", "content": "Skin hypersensitivity to parainfluenza-3 virus in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358500"}
{"pmid": "4358502", "title": "The aetiology of perceptive deafness. A clinico-pathological and anatomical study of temporal bones and brain structures.", "content": "The aetiology of perceptive deafness. A clinico-pathological and anatomical study of temporal bones and brain structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358502"}
{"pmid": "4358504", "title": "Making referrals is everybody's business.", "content": "Making referrals is everybody's business.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358504"}
{"pmid": "4358505", "title": "Dynamic response of the intact canine adrenal to infused ACTH.", "content": "Dynamic response of the intact canine adrenal to infused ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358505"}
{"pmid": "4358506", "title": "Systems analysis of arterial pressure regulation and hypertension.", "content": "Systems analysis of arterial pressure regulation and hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358506"}
{"pmid": "4358507", "title": "Influence of binding on the pharmacologic activity of antibiotics.", "content": "Influence of binding on the pharmacologic activity of antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358507"}
{"pmid": "4358510", "title": "The utilization of fluorescent microscopy in routine chromosome analysis.", "content": "The utilization of fluorescent microscopy in routine chromosome analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358510"}
{"pmid": "4358511", "title": "Contraceptive usage among teenagers.", "content": "Contraceptive usage among teenagers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358511"}
{"pmid": "4358512", "title": "Suicide in children and adolescents.", "content": "Suicide in children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358512"}
{"pmid": "4358513", "title": "Nepotism: paradoxical liberation.", "content": "Nepotism: paradoxical liberation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358513"}
{"pmid": "4358514", "title": "The management of emotional crises by medical practitioners.", "content": "The management of emotional crises by medical practitioners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358514"}
{"pmid": "4358515", "title": "Metatarsalgic neurogenica. A definitive clinical syndrome.", "content": "Metatarsalgic neurogenica. A definitive clinical syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358515"}
{"pmid": "4358519", "title": "The quantity and estrogenic activity of F-2 toxin produced on different substrates.", "content": "The quantity and estrogenic activity of F-2 toxin produced on different substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358519"}
{"pmid": "4358525", "title": "Experimental study on combined therapy with anticancer drugs and urokinase.", "content": "Experimental study on combined therapy with anticancer drugs and urokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358525"}
{"pmid": "4358527", "title": "Parotid benign giant mixed tumor of forty-two years duration with malignant transformation.", "content": "Parotid benign giant mixed tumor of forty-two years duration with malignant transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358527"}
{"pmid": "4358518", "title": "Possible aetiological factors of calciphylaxis in pigs.", "content": "Possible aetiological factors of calciphylaxis in pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358518"}
{"pmid": "4358530", "title": "Hepatoma in a mangabey (Cercocebus atys).", "content": "Hepatoma in a mangabey (Cercocebus atys).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358530"}
{"pmid": "4358531", "title": "Pneumoconiosis in the captive New Zealand kiwi.", "content": "Pneumoconiosis in the captive New Zealand kiwi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358531"}
{"pmid": "4358529", "title": "Neonatal calf diarrhea. Electron microscopy of intestines infected with a reovirus-like agent.", "content": "Neonatal calf diarrhea. Electron microscopy of intestines infected with a reovirus-like agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358529"}
{"pmid": "4358533", "title": "Breast carcinoma with late recurrence (cytological type 3).", "content": "Breast carcinoma with late recurrence (cytological type 3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358533"}
{"pmid": "4358534", "title": "Epstein-Barr virus infection in the neonatal period and in childhood.", "content": "Epstein-Barr virus infection in the neonatal period and in childhood. In an attempt to detect and characterize congenital, neonatal and early childhood EBV infections, a prospective sero-epidemiological study was undertaken in 112 newborn infants and their mothers, 25 additional newborns undergoing exchange transfusion, 114 randomly selected hospitalized infants aged 0 to 3 years, and 109 siblings and parents of these infants. Leukocyte culture was attempted in all the newborns and in 25 pre- and post-transfusion.The findings of EBV seroconversion in six patients without clearly apparent illness, infectious mononucleosis in only one case with significant EBV antibody rise, seroreversion in three cases in early childhood, higher newborn than maternal EBV antibody titres in three cases and the establishment of two permanent lymphoblastoid cell lines from newborns following exchange transfusion raise the possibility of abortive primary EBV infection in early life. Congenital or neonatal infections following exchange transfusions, however, could not be substantiated with certainty since the EBV antibodies did not persist at follow-up except possibly in two cases. Parenteral transmission of the EB virus by exchange transfusion at birth is probably prevented by the presence of EBV antibodies in either donor or recipient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358534"}
{"pmid": "4358535", "title": "Epstein-Barr virus infections.", "content": "Epstein-Barr virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358535"}
{"pmid": "4358536", "title": "Relationship of antigenicity of melanoma cells grown in 5-bromodeoxyuridine to reduced tumorigenicity.", "content": "Relationship of antigenicity of melanoma cells grown in 5-bromodeoxyuridine to reduced tumorigenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358536"}
{"pmid": "4358537", "title": "Polyadenylate-containing RNA of polyribosomes isolated from rat liver and Morris hepatoma 7800.", "content": "Polyadenylate-containing RNA of polyribosomes isolated from rat liver and Morris hepatoma 7800.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358537"}
{"pmid": "4358539", "title": "Comparison of surface material, cytoplasmic filaments, and intercellular junctions from untransformed and two mouse sarcoma virus-transformed cell lines.", "content": "Comparison of surface material, cytoplasmic filaments, and intercellular junctions from untransformed and two mouse sarcoma virus-transformed cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358539"}
{"pmid": "4358538", "title": "Ultrastructural comparison between the distribution of concanavalin A and wheat germ agglutinin cell surface receptors of normal and transformed hamster and rat cell lines.", "content": "Ultrastructural comparison between the distribution of concanavalin A and wheat germ agglutinin cell surface receptors of normal and transformed hamster and rat cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358538"}
{"pmid": "4358540", "title": "Enhancement of adenovirus transformation by treatment of hamster embryo cells with diverse chemical carcinogens.", "content": "Enhancement of adenovirus transformation by treatment of hamster embryo cells with diverse chemical carcinogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358540"}
{"pmid": "4358541", "title": "Dietary enhancement of nitrosamine carcinogenesis.", "content": "Dietary enhancement of nitrosamine carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358541"}
{"pmid": "4358542", "title": "Rapid two-dimensional immunoelectrophoresis of human serum proteins.", "content": "Rapid two-dimensional immunoelectrophoresis of human serum proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358542"}
{"pmid": "4358544", "title": "A light and electron microscopic study in serial sections of dystrophic extraocular muscle fibers.", "content": "A light and electron microscopic study in serial sections of dystrophic extraocular muscle fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358544"}
{"pmid": "4358545", "title": "Human adrenal tumors and hyperplasias in vitro: a bridge between morphology and function.", "content": "Human adrenal tumors and hyperplasias in vitro: a bridge between morphology and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358545"}
{"pmid": "4358546", "title": "Oxytyrosinase.", "content": "Oxytyrosinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358546"}
{"pmid": "4358547", "title": "Relation between the ribosomal sites involved in initiation and elongation of polypeptide chains. Evidence for two guanosine triphosphatase sites.", "content": "Relation between the ribosomal sites involved in initiation and elongation of polypeptide chains. Evidence for two guanosine triphosphatase sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358547"}
{"pmid": "4358548", "title": "Isolation and properties of a ribosome-bound factor required for ppGpp and ppGpp synthesis in Escherichia coli.", "content": "Isolation and properties of a ribosome-bound factor required for ppGpp and ppGpp synthesis in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358548"}
{"pmid": "4358549", "title": "Regulatory properties of perchlorate-extracted succinate dehydrogenase.", "content": "Regulatory properties of perchlorate-extracted succinate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358549"}
{"pmid": "4358550", "title": "Amino acid sequence of cytochrome c3 from Desulfovibrio vulgaris.", "content": "Amino acid sequence of cytochrome c3 from Desulfovibrio vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358550"}
{"pmid": "4358551", "title": "Early photoinduced enzymes of photoinduced carotenogenesis in a Mycobacterium species.", "content": "Early photoinduced enzymes of photoinduced carotenogenesis in a Mycobacterium species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358551"}
{"pmid": "4358552", "title": "Hormone receptors. 3. Properties of glucagon-binding proteins isolated from liver plasma membranes.", "content": "Hormone receptors. 3. Properties of glucagon-binding proteins isolated from liver plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358552"}
{"pmid": "4358554", "title": "Self-association and allosteric properties of glutamine-dependent carbamyl phosphate synthetase. Reversible dissociation to monomeric species.", "content": "Self-association and allosteric properties of glutamine-dependent carbamyl phosphate synthetase. Reversible dissociation to monomeric species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358554"}
{"pmid": "4358553", "title": "Regulated in vitro synthesis of Escherichia coli tryptophan operon messenger ribonucleic acid and enzymes.", "content": "Regulated in vitro synthesis of Escherichia coli tryptophan operon messenger ribonucleic acid and enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358553"}
{"pmid": "4358556", "title": "Effects of ouabain on catecholamine-stimulated sodium transport in turkey erythrocytes.", "content": "Effects of ouabain on catecholamine-stimulated sodium transport in turkey erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358556"}
{"pmid": "4358555", "title": "Reversible dissociation of the monomer of glutamine-dependent carbamyl phosphate synthetase into catalytically active heavy and light subunits.", "content": "Reversible dissociation of the monomer of glutamine-dependent carbamyl phosphate synthetase into catalytically active heavy and light subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358555"}
{"pmid": "4358557", "title": "Adenosine 3':5'-monophosphate-dependent protein kinase from yeast.", "content": "Adenosine 3':5'-monophosphate-dependent protein kinase from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358557"}
{"pmid": "4358560", "title": "A proton relaxation rate study of the copper analog of Escherichia coli alkaline phosphatase.", "content": "A proton relaxation rate study of the copper analog of Escherichia coli alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358560"}
{"pmid": "4358559", "title": "The structure of the abortive diphosphopyridine nucleotide-pyruvate-lactate dehydrogenase ternary complex as determined by proton magnetic resonance analysis.", "content": "The structure of the abortive diphosphopyridine nucleotide-pyruvate-lactate dehydrogenase ternary complex as determined by proton magnetic resonance analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358559"}
{"pmid": "4358558", "title": "Characterization of the serum high density lipoprotein and apolipoproteins of pink salmon.", "content": "Characterization of the serum high density lipoprotein and apolipoproteins of pink salmon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358558"}
{"pmid": "4358561", "title": "Blocks in ganglioside synthesis in transformed hamster cells and their revertants.", "content": "Blocks in ganglioside synthesis in transformed hamster cells and their revertants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358561"}
{"pmid": "4358562", "title": "Angiotensin II receptors in bovine adrenal cortex. Modification of angiotensin II binding by guanyl nucleotides.", "content": "Angiotensin II receptors in bovine adrenal cortex. Modification of angiotensin II binding by guanyl nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358562"}
{"pmid": "4358565", "title": "The nature of myelinated nerve fiber degeneration in dominantly inherited hypertrophic neuropathy.", "content": "The nature of myelinated nerve fiber degeneration in dominantly inherited hypertrophic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358565"}
{"pmid": "4358566", "title": "The role of cyclic AMP in mesenteric vasodilation.", "content": "The role of cyclic AMP in mesenteric vasodilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358566"}
{"pmid": "4358567", "title": "Involvement of alpha-receptors in clonidine-induced inhibition of transmitter release from central monoamine neurones.", "content": "Involvement of alpha-receptors in clonidine-induced inhibition of transmitter release from central monoamine neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358567"}
{"pmid": "4358568", "title": "Dopaminergic denervation supersensitivity and dopamine stimulated adenyl cyclase activity.", "content": "Dopaminergic denervation supersensitivity and dopamine stimulated adenyl cyclase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358568"}
{"pmid": "4358570", "title": "The influence of 1-(5-oxohexyl-)3.7-dimethylxanthine (BL 191) on the endocrine and exocrine pancreatic function in man during and following secretin and cholecystokinin-pancreozymin stimulation.", "content": "The influence of 1-(5-oxohexyl-)3.7-dimethylxanthine (BL 191) on the endocrine and exocrine pancreatic function in man during and following secretin and cholecystokinin-pancreozymin stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358570"}
{"pmid": "4358563", "title": "Presence of collagenase from Clostridium histolyticum in gingival sulcal debris of a primitive population.", "content": "Presence of collagenase from Clostridium histolyticum in gingival sulcal debris of a primitive population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358563"}
{"pmid": "4358564", "title": "Evaluation of collagenase activity in the crevicular fluid of children.", "content": "Evaluation of collagenase activity in the crevicular fluid of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358564"}
{"pmid": "4358576", "title": "Paradoxical increase in rate of catabolism of low-density lipoproteins after hepatectomy.", "content": "Paradoxical increase in rate of catabolism of low-density lipoproteins after hepatectomy. It has been suggested that the liver may be a major site for irreversible degradation of low-density lipoprotein (LDL). The disappearance of autologous (125)I-labeled LDL from plasma was compared in intact and in hepatectomized swine. Contrary to expectations, the rate of irreversible removal of LDL from plasma was increased rather then decreased by hepatectomy. These studies suggest that the liver is not a major site for LDL removal. We propose further that the liver (or some function requiring an intact liver) may affect the metabolism of LDL in a manner that prolongs its lifetime in the plasma compartment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358576"}
{"pmid": "4358577", "title": "Cyclic adenosine monophosphate: selective increase in caudate nucleus after administration of L-dopa.", "content": "Cyclic adenosine monophosphate: selective increase in caudate nucleus after administration of L-dopa. Treatment with the dopamine precursor L-dopa produced a significant accumulation of adenosine 3',5'-monophosphate (cyclic AMP) in the caudate nucleus of the rat. In contrast, there was no change in the amount of cyclic AMP in the cerebellum. Accumulation of cyclic AMP in the caudate nucleus after administration of L-dopa was prevented by prior treatment with the decarboxylase inhibitor RO 4-4602. These observations and those in other laboratories support the assumption that dopamine formed from L-dopa selectively activates striatal adenylate cyclase. The in vivo activation of adenylate cyclase after treatment with L-dopa may be a useful model for studying neurological and psychiatric disorders that are thought to involve the dopaminergic system of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358577"}
{"pmid": "4358578", "title": "Acute gastroenteritis associated with echovirus type 1.", "content": "Acute gastroenteritis associated with echovirus type 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358578"}
{"pmid": "4358582", "title": "The effect of 1-nitro-9-aminoacridine on respiration and glycolysis in Ehrlich ascites tumour cells.", "content": "The effect of 1-nitro-9-aminoacridine on respiration and glycolysis in Ehrlich ascites tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358582"}
{"pmid": "4358583", "title": "Alkylation of cytidine-5'-phosphate: mechanisms of alkylation, influence of O'-alkylation on susceptibility of pyrimidine nucleotides to some nucleolytic enzymes, and synthesis of 2'-O-alkyl polynucleotides.", "content": "Alkylation of cytidine-5'-phosphate: mechanisms of alkylation, influence of O'-alkylation on susceptibility of pyrimidine nucleotides to some nucleolytic enzymes, and synthesis of 2'-O-alkyl polynucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358583"}
{"pmid": "4358584", "title": "Preparative photochemical synthesis of isoguanosine ribo- and deoxyribonucleosides and nucleotides, and isoguanosine-3',5'-cyclic phosphate, a new cAMP analogue.", "content": "Preparative photochemical synthesis of isoguanosine ribo- and deoxyribonucleosides and nucleotides, and isoguanosine-3',5'-cyclic phosphate, a new cAMP analogue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358584"}
{"pmid": "4358587", "title": "The effect of ethanol on hemostatic properties of human blood platelets.", "content": "The effect of ethanol on hemostatic properties of human blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358587"}
{"pmid": "4358585", "title": "Manganese induced histochemical and histological alterations in gastrointestinal mucosa of guinea pigs.", "content": "Manganese induced histochemical and histological alterations in gastrointestinal mucosa of guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358585"}
{"pmid": "4358586", "title": "A correlation study between adrenal function and the duration of sustained ACTH treatments in the rat.", "content": "A correlation study between adrenal function and the duration of sustained ACTH treatments in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358586"}
{"pmid": "4358588", "title": "Clinical manifestations of hepatoma. A review of 6 years' experience at a cancer hospital.", "content": "Clinical manifestations of hepatoma. A review of 6 years' experience at a cancer hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358588"}
{"pmid": "4358580", "title": "Action of polymyxin B on bacterial membranes. 1. Binding to the O-antigenic lipopolysaccharide of Salmonella typhimurium.", "content": "Action of polymyxin B on bacterial membranes. 1. Binding to the O-antigenic lipopolysaccharide of Salmonella typhimurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358580"}
{"pmid": "4358589", "title": "The Child Mental Health Specialist: a new profession.", "content": "The Child Mental Health Specialist: a new profession.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358589"}
{"pmid": "4358591", "title": "Quantitation of bovine papilloma virus and serum antibody by immunodiffusion.", "content": "Quantitation of bovine papilloma virus and serum antibody by immunodiffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358591"}
{"pmid": "4358590", "title": "Family structure, aftercare, and post-hospital adjustment.", "content": "Family structure, aftercare, and post-hospital adjustment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358590"}
{"pmid": "4358592", "title": "Mixed leukocyte culture test in dogs.", "content": "Mixed leukocyte culture test in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358592"}
{"pmid": "4358594", "title": "Biological characteristics and viral susceptibility of a rat embryonic skin cell line (RESI).", "content": "Biological characteristics and viral susceptibility of a rat embryonic skin cell line (RESI).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358594"}
{"pmid": "4358593", "title": "The use of passive hemagglutination for the detection of bluetongue viral antibodies.", "content": "The use of passive hemagglutination for the detection of bluetongue viral antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358593"}
{"pmid": "4358595", "title": "The politics of empiricism. Research recommendations of the Joint Commission on Mental Health of Children.", "content": "The politics of empiricism. Research recommendations of the Joint Commission on Mental Health of Children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358595"}
{"pmid": "4358596", "title": "Morphologic effects of minocycline on the cochlea of the guinea pig.", "content": "Morphologic effects of minocycline on the cochlea of the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358596"}
{"pmid": "4358598", "title": "Ultrastructural study of clostridial myositis.", "content": "Ultrastructural study of clostridial myositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358598"}
{"pmid": "4358599", "title": "Pituitary gland in patients with Hurler syndrome. Light and electron microscopic study.", "content": "Pituitary gland in patients with Hurler syndrome. Light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358599"}
{"pmid": "4358600", "title": "Improved purification and further characterization of Clostridium perfringens type A enterotoxin.", "content": "Improved purification and further characterization of Clostridium perfringens type A enterotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358600"}
{"pmid": "4358601", "title": "Immunofluorescence of peritoneal phagocytes after infection in vivo with egg-attenuated Chlamydia psittaci 6BC.", "content": "Immunofluorescence of peritoneal phagocytes after infection in vivo with egg-attenuated Chlamydia psittaci 6BC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358601"}
{"pmid": "4358604", "title": "Mode of action of N6-O2'-dibutyryl cyclic 3',5' AMP on fat cell metabolism.", "content": "Mode of action of N6-O2'-dibutyryl cyclic 3',5' AMP on fat cell metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358604"}
{"pmid": "4358605", "title": "Antilipolytic action of tolbutamide in isolated fat cells of the rat.", "content": "Antilipolytic action of tolbutamide in isolated fat cells of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358605"}
{"pmid": "4358606", "title": "Induction of liver and lung tumours in rats by the simultaneous administration of sodium nitrite and morpholine.", "content": "Induction of liver and lung tumours in rats by the simultaneous administration of sodium nitrite and morpholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358606"}
{"pmid": "4358609", "title": "The structure of ferrocytochrome c at 2.45 A resolution.", "content": "The structure of ferrocytochrome c at 2.45 A resolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358609"}
{"pmid": "4358608", "title": "Human high density lipoprotein, apolipoprotein glutamine II. The immunochemical and lipid-binding properties of apolipoprotein glutamine II derivatives.", "content": "Human high density lipoprotein, apolipoprotein glutamine II. The immunochemical and lipid-binding properties of apolipoprotein glutamine II derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358608"}
{"pmid": "4358610", "title": "Adenosine cyclic 3':5'-monophosphate-dependent protein kinase from rabbit erythrocytes. Purification and characterization of multiple forms.", "content": "Adenosine cyclic 3':5'-monophosphate-dependent protein kinase from rabbit erythrocytes. Purification and characterization of multiple forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358610"}
{"pmid": "4358612", "title": "Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. I. Effect of nuclear mutations on mitochondrial protein synthesis.", "content": "Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. I. Effect of nuclear mutations on mitochondrial protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358612"}
{"pmid": "4358611", "title": "Hormonal control of glycogenolysis and gluconeogenesis in isolated rat liver cells.", "content": "Hormonal control of glycogenolysis and gluconeogenesis in isolated rat liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358611"}
{"pmid": "4358613", "title": "Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. II. Effect of nuclear and extrachromosomal mutations on the formation of cytochrome c oxidase.", "content": "Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. II. Effect of nuclear and extrachromosomal mutations on the formation of cytochrome c oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358613"}
{"pmid": "4358614", "title": "Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. 3. A nuclear mutant lacking mitochondrial adenosine triphosphatase.", "content": "Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. 3. A nuclear mutant lacking mitochondrial adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358614"}
{"pmid": "4358615", "title": "Stoichiometry of adenosine triphosphate-driven proton translocation in bovine heart submitochondrial particles.", "content": "Stoichiometry of adenosine triphosphate-driven proton translocation in bovine heart submitochondrial particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358615"}
{"pmid": "4358617", "title": "Protein hydration changes in the formation of the nicotinamide adenine dinucleotide complexes of glyceraldehyde 3-phosphate dehydrogenase of yeast. I. Buoyant densities, preferential hydrations, and fluorescence-quenching titrations.", "content": "Protein hydration changes in the formation of the nicotinamide adenine dinucleotide complexes of glyceraldehyde 3-phosphate dehydrogenase of yeast. I. Buoyant densities, preferential hydrations, and fluorescence-quenching titrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358617"}
{"pmid": "4358618", "title": "Protein hydration changes in the formation of the nicotinamide adenine dinucleotide complexes of glyceraldehyde 3-phosphate dehydrogenase of yeast. II. The spin lattice relaxation of solvent water protons.", "content": "Protein hydration changes in the formation of the nicotinamide adenine dinucleotide complexes of glyceraldehyde 3-phosphate dehydrogenase of yeast. II. The spin lattice relaxation of solvent water protons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358618"}
{"pmid": "4358616", "title": "Intracellular localization of enzymes of arginine metabolism in Neurospora.", "content": "Intracellular localization of enzymes of arginine metabolism in Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358616"}
{"pmid": "4358619", "title": "Sheep liver 6-phosphogluconate dehydrogenase. Inhibition by nucleoside phosphates and by other metabolic intermediates.", "content": "Sheep liver 6-phosphogluconate dehydrogenase. Inhibition by nucleoside phosphates and by other metabolic intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358619"}
{"pmid": "4358620", "title": "Regulation of steroidogenesis by adrenocorticotropic hormone in isolated adrenal cells of rats.", "content": "Regulation of steroidogenesis by adrenocorticotropic hormone in isolated adrenal cells of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358620"}
{"pmid": "4358621", "title": "Chemical and enzymatic evidence for the participation of a 2-carboxy-3-ketoribitol-1,5-diphosphate intermediate in the carboxylation of ribulose 1,5-diphosphate.", "content": "Chemical and enzymatic evidence for the participation of a 2-carboxy-3-ketoribitol-1,5-diphosphate intermediate in the carboxylation of ribulose 1,5-diphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358621"}
{"pmid": "4358622", "title": "Site-directed spin labeling of the mitochondrial membrane. Synthesis and utilization of the adenosine triphosphatase inhibitor (N-(2, 2, 6, 6-tetramethyl-piperidyl-1-oxyl)-N'-(cyclohexyl)-carbodiimide).", "content": "Site-directed spin labeling of the mitochondrial membrane. Synthesis and utilization of the adenosine triphosphatase inhibitor (N-(2, 2, 6, 6-tetramethyl-piperidyl-1-oxyl)-N'-(cyclohexyl)-carbodiimide).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358622"}
{"pmid": "4358624", "title": "Evidence for a dissociable glucagon binding site in a solubilized preparation of myocardial adenylate cyclase.", "content": "Evidence for a dissociable glucagon binding site in a solubilized preparation of myocardial adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358624"}
{"pmid": "4358625", "title": "The involvement of ribonuclease I, ribonuclease II, and polynucleotide phosphorylase in the degradation of stable ribonucleic acid during carbon starvation in Escherichia coli.", "content": "The involvement of ribonuclease I, ribonuclease II, and polynucleotide phosphorylase in the degradation of stable ribonucleic acid during carbon starvation in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358625"}
{"pmid": "4358623", "title": "A general method of tritium labeling utilizing microwave discharge activation of tritium gas. Methodology and application to biological compounds.", "content": "A general method of tritium labeling utilizing microwave discharge activation of tritium gas. Methodology and application to biological compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358623"}
{"pmid": "4358626", "title": "Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate dehydrogenase from Pisum sativum. Purification and characterization.", "content": "Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate dehydrogenase from Pisum sativum. Purification and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358626"}
{"pmid": "4358627", "title": "Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate dehydrogenase from Pisum sativum. Assay and steady state kinetics.", "content": "Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate dehydrogenase from Pisum sativum. Assay and steady state kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358627"}
{"pmid": "4358628", "title": "Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate dehydrogenase from Pisum sativum. Effect of nicotinamide adenine dinucleotide and related compounds on the enzyme-catalyzed arsenolysis of 1,3-diphosphoglyceric acid.", "content": "Nicotinamide adenine dinucleotide-specific glyceraldehyde 3-phosphate dehydrogenase from Pisum sativum. Effect of nicotinamide adenine dinucleotide and related compounds on the enzyme-catalyzed arsenolysis of 1,3-diphosphoglyceric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358628"}
{"pmid": "4358629", "title": "The nucleotide sequence adjoining the CCA end of an Escherichia coli tyrosine transfer ribonucleic acid gene.", "content": "The nucleotide sequence adjoining the CCA end of an Escherichia coli tyrosine transfer ribonucleic acid gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358629"}
{"pmid": "4358630", "title": "The mechanism of action of adrenocroticotropic hormone. The role of mitochondrial cholesterol accumulation in the regulation of steroidogenesis.", "content": "The mechanism of action of adrenocroticotropic hormone. The role of mitochondrial cholesterol accumulation in the regulation of steroidogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358630"}
{"pmid": "4358631", "title": "Angiotensinase activity of dipeptidyl aminopeptidase I (cathepsin C) of rat liver.", "content": "Angiotensinase activity of dipeptidyl aminopeptidase I (cathepsin C) of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358631"}
{"pmid": "4358632", "title": "Effect of cyclic adenosine 3':5'-monophosphate on ribosomal protein phosphorylation in reticulocytes.", "content": "Effect of cyclic adenosine 3':5'-monophosphate on ribosomal protein phosphorylation in reticulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358632"}
{"pmid": "4358634", "title": "Purification and properties of phosphoribosyl pyrophosphate synthetase from rat liver.", "content": "Purification and properties of phosphoribosyl pyrophosphate synthetase from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358634"}
{"pmid": "4358633", "title": "Estimation of the fructose 1,6-diphosphatase-phosphofructokinase substrate cycle and its relationship to gluconeogenesis in rat liver in vivo.", "content": "Estimation of the fructose 1,6-diphosphatase-phosphofructokinase substrate cycle and its relationship to gluconeogenesis in rat liver in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358633"}
{"pmid": "4358636", "title": "Purification of adenohypophyseal plasma membranes and properties of associated adenylate cyclase.", "content": "Purification of adenohypophyseal plasma membranes and properties of associated adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358636"}
{"pmid": "4358635", "title": "Stability and regulation of phosphoribosyl pyrophosphate synthetase from rat liver.", "content": "Stability and regulation of phosphoribosyl pyrophosphate synthetase from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358635"}
{"pmid": "4358637", "title": "Phosphorylation of adenohypophyseal plasma membranes and properties of associated protein kinase.", "content": "Phosphorylation of adenohypophyseal plasma membranes and properties of associated protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358637"}
{"pmid": "4358638", "title": "Nonenzymatic formation of guanosine 3':5'-monophosphate from guanosine triphosphate.", "content": "Nonenzymatic formation of guanosine 3':5'-monophosphate from guanosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358638"}
{"pmid": "4358639", "title": "Fractionation of 34 S ribonucleic acid subunits from oncornaviruses on polyuridylate-sepharose columns.", "content": "Fractionation of 34 S ribonucleic acid subunits from oncornaviruses on polyuridylate-sepharose columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358639"}
{"pmid": "4358640", "title": "Properties of follicle-stimulating hormone-receptor interactions. Specific binding of human follicle-stimulating hormone to rat testes.", "content": "Properties of follicle-stimulating hormone-receptor interactions. Specific binding of human follicle-stimulating hormone to rat testes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358640"}
{"pmid": "4358641", "title": "Evidence for interdependent action of glucagon and nucleotides on the hepatic adenylate cyclase system.", "content": "Evidence for interdependent action of glucagon and nucleotides on the hepatic adenylate cyclase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358641"}
{"pmid": "4358642", "title": "A gonadotropin-responsive adrenocortical adenoma.", "content": "A gonadotropin-responsive adrenocortical adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358642"}
{"pmid": "4358643", "title": "TSH stimulation of 32P incorporation into phospholipids of thyroids from patients with Graves' disease.", "content": "TSH stimulation of 32P incorporation into phospholipids of thyroids from patients with Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358643"}
{"pmid": "4358644", "title": "Control of refractory fasting hypoglycemia in a patient with suspected insulinoma with diphenylhydantoin.", "content": "Control of refractory fasting hypoglycemia in a patient with suspected insulinoma with diphenylhydantoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358644"}
{"pmid": "4358645", "title": "Estrogen receptor concentration in normal and pathological human uterine tissues.", "content": "Estrogen receptor concentration in normal and pathological human uterine tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358645"}
{"pmid": "4358646", "title": "Endocrine function in an anencephalic infant.", "content": "Endocrine function in an anencephalic infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358646"}
{"pmid": "4358647", "title": "Cyclic AMP accumulation and steroidogenesis in the human corpus luteum: effect of gonadotropins and prostaglandins.", "content": "Cyclic AMP accumulation and steroidogenesis in the human corpus luteum: effect of gonadotropins and prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358647"}
{"pmid": "4358648", "title": "Rhesus leukocyte-associated herpesvirus. I. Isolation and characterization of a new herpesvirus recovered from rhesus monkey leukocytes.", "content": "Rhesus leukocyte-associated herpesvirus. I. Isolation and characterization of a new herpesvirus recovered from rhesus monkey leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358648"}
{"pmid": "4358649", "title": "Rhesus leukocyte-associated herpesvirus. II. Natural and experimental infection.", "content": "Rhesus leukocyte-associated herpesvirus. II. Natural and experimental infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358649"}
{"pmid": "4358650", "title": "Evaluation of cholinesterase-restoring agents in the treatment of tetanus in man.", "content": "Evaluation of cholinesterase-restoring agents in the treatment of tetanus in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358650"}
{"pmid": "4358652", "title": "Viruses causing common respiratory infections in man. 3. Respiratory syncytial viruses and coronaviruses.", "content": "Viruses causing common respiratory infections in man. 3. Respiratory syncytial viruses and coronaviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358652"}
{"pmid": "4358651", "title": "Effect of adenine arabinoside on severe Herpesvirus hominis infections in man.", "content": "Effect of adenine arabinoside on severe Herpesvirus hominis infections in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358651"}
{"pmid": "4358654", "title": "Treatment of herpesvirus encephalitis with iododeoxyuridine.", "content": "Treatment of herpesvirus encephalitis with iododeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358654"}
{"pmid": "4358653", "title": "Ecthyma gangrenosum produced by Aeromonas hydrophilia.", "content": "Ecthyma gangrenosum produced by Aeromonas hydrophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358653"}
{"pmid": "4358655", "title": "Letter: Bilateral eventration of the diaphragm in a neonate with congenital cytomegalic inclusion disease.", "content": "Letter: Bilateral eventration of the diaphragm in a neonate with congenital cytomegalic inclusion disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358655"}
{"pmid": "4358656", "title": "Iatrogenic Cushing's disease in a boy after misdiagnosis of salt-losing virilizing adrenal hyperplasia: impaired metyrapone response with failure of catch-up growth.", "content": "Iatrogenic Cushing's disease in a boy after misdiagnosis of salt-losing virilizing adrenal hyperplasia: impaired metyrapone response with failure of catch-up growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358656"}
{"pmid": "4358657", "title": "Iodide goiter following lymphography.", "content": "Iodide goiter following lymphography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358657"}
{"pmid": "4358660", "title": "Hepatitis B antigen: removal from protein solutions in a recognizable form by an insoluble lipophilic matrix of silicic acid.", "content": "Hepatitis B antigen: removal from protein solutions in a recognizable form by an insoluble lipophilic matrix of silicic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358660"}
{"pmid": "4358661", "title": "Enzymatic hydrolysis of nucleoside phosphoramidates.", "content": "Enzymatic hydrolysis of nucleoside phosphoramidates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358661"}
{"pmid": "4358662", "title": "Chemical structure and absolute configuration of a juvenile hormone from grasshopper corpora allata in vitro.", "content": "Chemical structure and absolute configuration of a juvenile hormone from grasshopper corpora allata in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358662"}
{"pmid": "4358663", "title": "Cholesterol in cerebrospinal fluid of brain tumor patients.", "content": "Cholesterol in cerebrospinal fluid of brain tumor patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358663"}
{"pmid": "4358664", "title": "Fatty acid metabolism in denervated muscle of frog in vitro.", "content": "Fatty acid metabolism in denervated muscle of frog in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358664"}
{"pmid": "4358665", "title": "Congenital cytomegalovirus infection: consecutive occurrence due to viruses with similar antigenic compositions.", "content": "Congenital cytomegalovirus infection: consecutive occurrence due to viruses with similar antigenic compositions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358665"}
{"pmid": "4358666", "title": "Pharmacological interaction between cannabidiol and delta 9-tetrahydrocannabinol.", "content": "Pharmacological interaction between cannabidiol and delta 9-tetrahydrocannabinol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358666"}
{"pmid": "4358669", "title": "Cyclic AMP and its relation to clinical chemistry.", "content": "Cyclic AMP and its relation to clinical chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358669"}
{"pmid": "4358670", "title": "Urinary cyclic AMP excretion in toxaemia of pregnancy.", "content": "Urinary cyclic AMP excretion in toxaemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358670"}
{"pmid": "4358671", "title": "Pretreatment classification and staging of bronchogenic carcinoma.", "content": "Pretreatment classification and staging of bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358671"}
{"pmid": "4358673", "title": "Comparative electron microscopic studies on Pseudomonas aeruginosa endotoxin.", "content": "Comparative electron microscopic studies on Pseudomonas aeruginosa endotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358673"}
{"pmid": "4358678", "title": "Sleep of distance runners.", "content": "Sleep of distance runners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358678"}
{"pmid": "4358679", "title": "Ultrastructural study of neuronal cytoplasmic inclusions produced by hypocholesterolemic drug, AY 9944.", "content": "Ultrastructural study of neuronal cytoplasmic inclusions produced by hypocholesterolemic drug, AY 9944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358679"}
{"pmid": "4358680", "title": "Creutzfeldt-Jakob disease: a histochemical study with microdensitometric assay of some enzymes.", "content": "Creutzfeldt-Jakob disease: a histochemical study with microdensitometric assay of some enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358680"}
{"pmid": "4358681", "title": "Chemistry of iron in biological systems.", "content": "Chemistry of iron in biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358681"}
{"pmid": "4358682", "title": "90Y ferric hydroxide colloid.", "content": "90Y ferric hydroxide colloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358682"}
{"pmid": "4358676", "title": "Ribonuclease present in myxoviruses.", "content": "Ribonuclease present in myxoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358676"}
{"pmid": "4358683", "title": "Retention of 90Y in patients with rheumatoid arthritis.", "content": "Retention of 90Y in patients with rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358683"}
{"pmid": "4358675", "title": "On the receptor of influenza viruses. 1. Artificial receptor for influenza virus.", "content": "On the receptor of influenza viruses. 1. Artificial receptor for influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358675"}
{"pmid": "4358689", "title": "Organizational history of HSMHA.", "content": "Organizational history of HSMHA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358689"}
{"pmid": "4358687", "title": "Diaminopurine-resistant mutants of cultured, diploid human fibroblasts.", "content": "Diaminopurine-resistant mutants of cultured, diploid human fibroblasts. Clones of cells resistant to 2,6-diaminopurine were detected in skin fibroblast cultures derived from 13 of 21 normal humans of both sexes from 17 unrelated families. Almost all of the cultures that yielded mutants were chosen for further study from among a total of 83 surveyed because they displayed a slight resistance to low concentrations of diaminopurine. The incidences of mutant colonies ranged between about 10(-5) and 10(-4) per cell surviving prior mutagenic treatment with MNNG. The incidences of spontaneous mutants were about 10(-7) to 10(-5) in three unrelated cultures. Most independent mutants had distinctly reduced activity of adenine phosphoribosyltransferase but some had apparently normal amounts of activity. Two mutants from unrelated boys had little or no detectable enzyme activity and were unable to effectively use exogenous adenine for growth when purine biosynthesis was blocked with azaserine. Most mutants could utilize exogenous adenine, just as most azaguanine-resistant fibroblast mutants can utilize exogenous hypoxanthine, even when their hypoxanthine-guanine phosphoribosyltransferase activity is reduced. Diverse genetic changes conferred diaminopurine resistance but their specific natures are still undefined. Gross numerical or structural chromosome abnormalities were not observed in the mutants examined so far. Since at least one gene responsible for adenine phosphoribosyltransferase activity is on autosome No. 16 our results suggest that at least some of the cultures yielding mutants were heterozygous and that alleles conferring diaminopurine resistance may be frequent enough to comprise a polymorphism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358687"}
{"pmid": "4358690", "title": "The NIMH approach to evaluating the community mental health centers program.", "content": "The NIMH approach to evaluating the community mental health centers program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358690"}
{"pmid": "4358692", "title": "Electrotonic conduction in the optic nerves of planorbid snails.", "content": "Electrotonic conduction in the optic nerves of planorbid snails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358692"}
{"pmid": "4358693", "title": "Capacitation of epididymal spermatozoa in a medium with high K-Na ratio and cyclic AMP for the fertilization of rat eggs in vitro.", "content": "Capacitation of epididymal spermatozoa in a medium with high K-Na ratio and cyclic AMP for the fertilization of rat eggs in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358693"}
{"pmid": "4358694", "title": "Oestradiol-17beta: its influence on cyclic 3'5'-adenosine monophosphate phosphodiesterase and 5'-nucleotidase in the cervicovaginal epithelium of neonatal mice.", "content": "Oestradiol-17beta: its influence on cyclic 3'5'-adenosine monophosphate phosphodiesterase and 5'-nucleotidase in the cervicovaginal epithelium of neonatal mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358694"}
{"pmid": "4358685", "title": "Acute localized amebic appendicitis: report of a case.", "content": "Acute localized amebic appendicitis: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358685"}
{"pmid": "4358684", "title": "Early components of the averaged electroencephalic response to constant level clicks during rapid eye movement sleep.", "content": "Early components of the averaged electroencephalic response to constant level clicks during rapid eye movement sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358684"}
{"pmid": "4358700", "title": "Multilocular cysts of kidney.", "content": "Multilocular cysts of kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358700"}
{"pmid": "4358702", "title": "Renal cystography with triple-contrast material.", "content": "Renal cystography with triple-contrast material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358702"}
{"pmid": "4358701", "title": "Plasma renin activity. Comparison of bioassay and radioimmunoassay techniques.", "content": "Plasma renin activity. Comparison of bioassay and radioimmunoassay techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358701"}
{"pmid": "4358703", "title": "Adrenalectomy and hypophysectomy for prostatic cancer.", "content": "Adrenalectomy and hypophysectomy for prostatic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358703"}
{"pmid": "4358711", "title": "Alkaline and acid phosphatase activity in buffalo semen.", "content": "Alkaline and acid phosphatase activity in buffalo semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358711"}
{"pmid": "4358712", "title": "Adeno, parainfluenza, RS, and corona viruses and Mycoplasma pneumoniae as etiologic agents of acute respiratory tract infections.", "content": "Adeno, parainfluenza, RS, and corona viruses and Mycoplasma pneumoniae as etiologic agents of acute respiratory tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358712"}
{"pmid": "4358713", "title": "Serological surveillance of respiratory viruses in healthy population of the Koszalin Province.", "content": "Serological surveillance of respiratory viruses in healthy population of the Koszalin Province.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358713"}
{"pmid": "4358714", "title": "Seroepidemiological studies on the occurrence of several respiratory viruses in the population of the Lublin province.", "content": "Seroepidemiological studies on the occurrence of several respiratory viruses in the population of the Lublin province.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358714"}
{"pmid": "4358715", "title": "Typhoid-paratyphoid (TAB) vaccine as interferon inducer in mice.", "content": "Typhoid-paratyphoid (TAB) vaccine as interferon inducer in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358715"}
{"pmid": "4358717", "title": "Role of incomplete viruses and interferon in persistent infection of mouse cells with Sindbis virus.", "content": "Role of incomplete viruses and interferon in persistent infection of mouse cells with Sindbis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358717"}
{"pmid": "4358716", "title": "The in vitro effect of cyclophosphamide on Col. MM virus replication and interferon production.", "content": "The in vitro effect of cyclophosphamide on Col. MM virus replication and interferon production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358716"}
{"pmid": "4358718", "title": "Antiviral drugs in human therapy.", "content": "Antiviral drugs in human therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358718"}
{"pmid": "4358719", "title": "Studies on antiviral activity of alpha-trihalogenomethylamines.", "content": "Studies on antiviral activity of alpha-trihalogenomethylamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358719"}
{"pmid": "4358720", "title": "Latent virus infections in primary monkey kidney cultures.", "content": "Latent virus infections in primary monkey kidney cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358720"}
{"pmid": "4358723", "title": "Kinin-converting aminopeptidase from human serum.", "content": "Kinin-converting aminopeptidase from human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358723"}
{"pmid": "4358724", "title": "A comparative study of purine metabolism by human and pig erythrocytes in vitro.", "content": "A comparative study of purine metabolism by human and pig erythrocytes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358724"}
{"pmid": "4358725", "title": "Effects of adrenochrome and sodium perborate on isolated fat cell metabolism.", "content": "Effects of adrenochrome and sodium perborate on isolated fat cell metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358725"}
{"pmid": "4358728", "title": "Effects of chlorpromazine, thioridazine and haloperidol on adrenergic transmitter mechanisms in man.", "content": "Effects of chlorpromazine, thioridazine and haloperidol on adrenergic transmitter mechanisms in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358728"}
{"pmid": "4358729", "title": "Comparative effect of vincristine and alkylating agent No. 864 on rat leukemia in relation to the distribution of drugs and leukemic cells.", "content": "Comparative effect of vincristine and alkylating agent No. 864 on rat leukemia in relation to the distribution of drugs and leukemic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358729"}
{"pmid": "4358731", "title": "Distribution of 51Cr-labeled lymphoid cells in the lymph node draining the inoculated tumor in the rat.", "content": "Distribution of 51Cr-labeled lymphoid cells in the lymph node draining the inoculated tumor in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358731"}
{"pmid": "4358730", "title": "Synergistic effects of bis(3-methylsulfonyloxypropyl)-amine toluenesulfonate (864-T) with 6-mercaptopurine and other antitumor agents.", "content": "Synergistic effects of bis(3-methylsulfonyloxypropyl)-amine toluenesulfonate (864-T) with 6-mercaptopurine and other antitumor agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358730"}
{"pmid": "4358732", "title": "Type-C virus in cultured cells derived from normal and tumor cells of a rat.", "content": "Type-C virus in cultured cells derived from normal and tumor cells of a rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358732"}
{"pmid": "4358734", "title": "Hepatoblastoma.", "content": "Hepatoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358734"}
{"pmid": "4358735", "title": "Surgical anatomy of the intraglandular portion of the facial nerve.", "content": "Surgical anatomy of the intraglandular portion of the facial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358735"}
{"pmid": "4358736", "title": "Cytoplasmic and nuclear pyrimidine ribonucleotide pools in HeLa cells.", "content": "Cytoplasmic and nuclear pyrimidine ribonucleotide pools in HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358736"}
{"pmid": "4358737", "title": "Experiences with vulvar cancer.", "content": "Experiences with vulvar cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358737"}
{"pmid": "4358738", "title": "Inactivation of poliovirus in water by ozonation.", "content": "Inactivation of poliovirus in water by ozonation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358738"}
{"pmid": "4358739", "title": "Trichinosis--the Maryland outbreak of 1970.", "content": "Trichinosis--the Maryland outbreak of 1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358739"}
{"pmid": "4358741", "title": "Isolation and purification of surface antigens from disrupted paramyxoviruses.", "content": "Isolation and purification of surface antigens from disrupted paramyxoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358741"}
{"pmid": "4358742", "title": "The influence of polymyxin B on virus-induced cytopathogenic effect.", "content": "The influence of polymyxin B on virus-induced cytopathogenic effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358742"}
{"pmid": "4358743", "title": "Mitochondrial DNA synthesis in Raji cells infected by herpes simplex virus or Epstein-Barr virus.", "content": "Mitochondrial DNA synthesis in Raji cells infected by herpes simplex virus or Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358743"}
{"pmid": "4358749", "title": "Recovery of the antibody-forming potential in cyclophosphamide-treated mice, with special reference to the influence of Bordetella pertussis.", "content": "Recovery of the antibody-forming potential in cyclophosphamide-treated mice, with special reference to the influence of Bordetella pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358749"}
{"pmid": "4358750", "title": "Neurotransmitting substances and endotoxin respone in relation to hepatic enzyme induction.", "content": "Neurotransmitting substances and endotoxin respone in relation to hepatic enzyme induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358750"}
{"pmid": "4358751", "title": "Histochemical investigations into the lipid nature of the oil-droplet in the retinal twin-cones of Lebistes reticulatus (Peters). (With 5 figures).", "content": "Histochemical investigations into the lipid nature of the oil-droplet in the retinal twin-cones of Lebistes reticulatus (Peters). (With 5 figures).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358751"}
{"pmid": "4358752", "title": "Studies on RNA metabolism during lymphocyte activation.", "content": "Studies on RNA metabolism during lymphocyte activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358752"}
{"pmid": "4358758", "title": "Embryogenesis of Calliphora erythrocephala. 3. Ultrastructure of the midgut epithelial cells during late embryonic development.", "content": "Embryogenesis of Calliphora erythrocephala. 3. Ultrastructure of the midgut epithelial cells during late embryonic development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358758"}
{"pmid": "4358756", "title": "Histochemical and fine structure observations of the intestinal epithelium of Trichuris suis (Nematoda: Trichuroidea).", "content": "Histochemical and fine structure observations of the intestinal epithelium of Trichuris suis (Nematoda: Trichuroidea).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358756"}
{"pmid": "4358759", "title": "The fine structure of the spermatozoon of Littornia (Gastropoda: Prosobranchia), with special reference to sperm motility.", "content": "The fine structure of the spermatozoon of Littornia (Gastropoda: Prosobranchia), with special reference to sperm motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358759"}
{"pmid": "4358760", "title": "CSF contacting axons and synapses in the lumen of the pineal organ.", "content": "CSF contacting axons and synapses in the lumen of the pineal organ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358760"}
{"pmid": "4358762", "title": "Ultrastructural studies of the commensal suctorian, Choanophrya infundibulifera Hartog. I. Tentacle structure, movement and feeding.", "content": "Ultrastructural studies of the commensal suctorian, Choanophrya infundibulifera Hartog. I. Tentacle structure, movement and feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358762"}
{"pmid": "4358761", "title": "Ultrastructure of STH cells of the pars distalis of castrated male mice after hepatectomy.", "content": "Ultrastructure of STH cells of the pars distalis of castrated male mice after hepatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358761"}
{"pmid": "4358763", "title": "Ultrastructural studies of the commensal suctorian, Choanophrya infundibulifera Hartog. II. Tentacle morphogenesis.", "content": "Ultrastructural studies of the commensal suctorian, Choanophrya infundibulifera Hartog. II. Tentacle morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358763"}
{"pmid": "4358764", "title": "Structural connections between dense core vesicles in the central nervous system of Anodonta cygnea L. (Mollusca, Eulamellibranchia).", "content": "Structural connections between dense core vesicles in the central nervous system of Anodonta cygnea L. (Mollusca, Eulamellibranchia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358764"}
{"pmid": "4358765", "title": "Replication of swinepox virus in the skin of naturally infected pigs. Electron microscopic study.", "content": "Replication of swinepox virus in the skin of naturally infected pigs. Electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358765"}
{"pmid": "4358768", "title": "A guide to bone scanning.", "content": "A guide to bone scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358768"}
{"pmid": "4358770", "title": "Home care after peripheral vascular surgery.", "content": "Home care after peripheral vascular surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358770"}
{"pmid": "4358769", "title": "Spectrophotometric determination of free silica.", "content": "Spectrophotometric determination of free silica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358769"}
{"pmid": "4358754", "title": "The effect of pattern movement on the impulse activity of the cervical connective of Drosophila melanogaster.", "content": "The effect of pattern movement on the impulse activity of the cervical connective of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358754"}
{"pmid": "4358767", "title": "Intracerebral hemorrhage as initial symptom of a brain tumor.", "content": "Intracerebral hemorrhage as initial symptom of a brain tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358767"}
{"pmid": "4358776", "title": "Suppression of plasma ACTH levels with corticosteroids in Addison's disease.", "content": "Suppression of plasma ACTH levels with corticosteroids in Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358776"}
{"pmid": "4358777", "title": "Production of a corticotrophin-like intermediate lobe peptide and of corticotrophin by a bronchial carcinoid tumour.", "content": "Production of a corticotrophin-like intermediate lobe peptide and of corticotrophin by a bronchial carcinoid tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358777"}
{"pmid": "4358778", "title": "Plasma unconjugated and conjugated 17-hydroxycorticosteroids in different clinical disorders.", "content": "Plasma unconjugated and conjugated 17-hydroxycorticosteroids in different clinical disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358778"}
{"pmid": "4358771", "title": "The histological classification of malignant lung tumors.", "content": "The histological classification of malignant lung tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358771"}
{"pmid": "4358779", "title": "ACTH and MSH assays and their clinical application.", "content": "ACTH and MSH assays and their clinical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358779"}
{"pmid": "4358782", "title": "Establishing an alcoholism treatment program in a community hospital.", "content": "Establishing an alcoholism treatment program in a community hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358782"}
{"pmid": "4358783", "title": "Human cerebral blood flow during sleep and waking.", "content": "Human cerebral blood flow during sleep and waking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358783"}
{"pmid": "4358784", "title": "Studies on the circadian rhythm of phosphoenolpyruvate carboxykinase activity in rats. II. Effect of the autonomic nervous system on the rhythm in liver.", "content": "Studies on the circadian rhythm of phosphoenolpyruvate carboxykinase activity in rats. II. Effect of the autonomic nervous system on the rhythm in liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358784"}
{"pmid": "4358785", "title": "Glyceraldehyde 3-phosphate dehydrogenase of Bacillus stearothermophilus. Kinetics and physicochemical studies.", "content": "Glyceraldehyde 3-phosphate dehydrogenase of Bacillus stearothermophilus. Kinetics and physicochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358785"}
{"pmid": "4358786", "title": "Interaction of yeast alcohol dehydrogenase with various substrates. I. Binding of coenzymes.", "content": "Interaction of yeast alcohol dehydrogenase with various substrates. I. Binding of coenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358786"}
{"pmid": "4358788", "title": "Disseminated herpesvirus infection in a rhesus monkey (Macaca mulatta).", "content": "Disseminated herpesvirus infection in a rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358788"}
{"pmid": "4358794", "title": "The differential capacity of a nerve channel.", "content": "The differential capacity of a nerve channel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358794"}
{"pmid": "4358796", "title": "Response of specific skin hypersensitivity and haemagglutination inhibiting antibody after smallpox vaccination in human newborns and adults.", "content": "Response of specific skin hypersensitivity and haemagglutination inhibiting antibody after smallpox vaccination in human newborns and adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358796"}
{"pmid": "4358801", "title": "Effects of chronic alcohol abuse on the fatty acid composition of major lipids in the human brain. Hepatocerebral degeneration II.", "content": "Effects of chronic alcohol abuse on the fatty acid composition of major lipids in the human brain. Hepatocerebral degeneration II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358801"}
{"pmid": "4358803", "title": "Cerebrospinal fluid cholesterol. Quantitative analysis of unesterified and esterified cholesterol and normal values in the cerebrospinal fluid.", "content": "Cerebrospinal fluid cholesterol. Quantitative analysis of unesterified and esterified cholesterol and normal values in the cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358803"}
{"pmid": "4358790", "title": "Cerebral lipids in experimental cyanide encephalopathy.", "content": "Cerebral lipids in experimental cyanide encephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358790"}
{"pmid": "4358804", "title": "Correlation between hypothalamic serotonin content and adrenal function during acute stress. Effect of adrenal corticosteroids on hypothalamic serotonin content.", "content": "Correlation between hypothalamic serotonin content and adrenal function during acute stress. Effect of adrenal corticosteroids on hypothalamic serotonin content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358804"}
{"pmid": "4358805", "title": "Staphylococcus epidermidis isolated from bovine milk. Biochemical properties, phage sensitivity and pathogenicity for the udder.", "content": "Staphylococcus epidermidis isolated from bovine milk. Biochemical properties, phage sensitivity and pathogenicity for the udder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358805"}
{"pmid": "4358810", "title": "The kinetic and redox potentiometric resolution of the carotenoid shifts in Rhodopseudomonas spheroides chromatophores: their relationship to electric field alterations in electron transport and energy coupling.", "content": "The kinetic and redox potentiometric resolution of the carotenoid shifts in Rhodopseudomonas spheroides chromatophores: their relationship to electric field alterations in electron transport and energy coupling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358810"}
{"pmid": "4358811", "title": "Biochemical and biophysical studies on cytochrome c oxidase. XI. Reaction with azide.", "content": "Biochemical and biophysical studies on cytochrome c oxidase. XI. Reaction with azide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358811"}
{"pmid": "4358812", "title": "Mitochondrial metabolism in porphyric rat liver.", "content": "Mitochondrial metabolism in porphyric rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358812"}
{"pmid": "4358814", "title": "Biochemical and biophysical studies on cytochrome c oxidase. XII. Kinetics of azide binding.", "content": "Biochemical and biophysical studies on cytochrome c oxidase. XII. Kinetics of azide binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358814"}
{"pmid": "4358813", "title": "A new cytochrome b-like pigment with a peak at 567 nm and a low redox potential in denitrifying bacteria.", "content": "A new cytochrome b-like pigment with a peak at 567 nm and a low redox potential in denitrifying bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358813"}
{"pmid": "4358815", "title": "A simple method for the purification of commercial neuraminidase preparations free from proteases.", "content": "A simple method for the purification of commercial neuraminidase preparations free from proteases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358815"}
{"pmid": "4358816", "title": "Studies on a pyrophosphatase and glucose-6-phosphatase from Aspergillus oryzae.", "content": "Studies on a pyrophosphatase and glucose-6-phosphatase from Aspergillus oryzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358816"}
{"pmid": "4358817", "title": "Letter: Singlet oxygen decontaminating activity of erythrocuprein (superoxide dismutase).", "content": "Letter: Singlet oxygen decontaminating activity of erythrocuprein (superoxide dismutase).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358817"}
{"pmid": "4358820", "title": "Prednisolone for idiopathic (Bell's) facial palsy.", "content": "Prednisolone for idiopathic (Bell's) facial palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358820"}
{"pmid": "4358818", "title": "Conformational changes of aspartate aminotransferases in the region of Cys-45 residue observed by means of spin label.", "content": "Conformational changes of aspartate aminotransferases in the region of Cys-45 residue observed by means of spin label.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358818"}
{"pmid": "4358821", "title": "Molecular properties of lactic dehydrogenase under the conditions of the enzymatic test. Sedimentation analysis and gel filtration in the microgram and nanogram range.", "content": "Molecular properties of lactic dehydrogenase under the conditions of the enzymatic test. Sedimentation analysis and gel filtration in the microgram and nanogram range.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358821"}
{"pmid": "4358819", "title": "Synthesis of glucose-6-phosphate by a I,3-diphosphoglycerate-glucose phosphotransferase activity of liver microsomes.", "content": "Synthesis of glucose-6-phosphate by a I,3-diphosphoglycerate-glucose phosphotransferase activity of liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358819"}
{"pmid": "4358822", "title": "Pathways for the oxidation of malate and reduced pyridine nucleotide by wheat mitochondria.", "content": "Pathways for the oxidation of malate and reduced pyridine nucleotide by wheat mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358822"}
{"pmid": "4358823", "title": "Effect of temperature on the behavior of rat-liver mitochondria during centrifugation in a sucrose gradient.", "content": "Effect of temperature on the behavior of rat-liver mitochondria during centrifugation in a sucrose gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358823"}
{"pmid": "4358830", "title": "Effects of hypnotic induction and suggestions on nocturnal dreaming and thinking.", "content": "Effects of hypnotic induction and suggestions on nocturnal dreaming and thinking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358830"}
{"pmid": "4358831", "title": "Equine infectious anemia: a retrospective study of an epizootic.", "content": "Equine infectious anemia: a retrospective study of an epizootic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358831"}
{"pmid": "4358832", "title": "Combined (B- and T-lymphocyte) immunodeficiency: a fatal genetic disease in Arabian foals.", "content": "Combined (B- and T-lymphocyte) immunodeficiency: a fatal genetic disease in Arabian foals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358832"}
{"pmid": "4358833", "title": "Carotid baroreceptor modulation of diaphragm and abdominal muscle activity in the cat.", "content": "Carotid baroreceptor modulation of diaphragm and abdominal muscle activity in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358833"}
{"pmid": "4358834", "title": "Intranuclear rods and sheets in rat cochlear nucleus.", "content": "Intranuclear rods and sheets in rat cochlear nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358834"}
{"pmid": "4358835", "title": "The fine structure of freeze-fractured presynaptic membranes.", "content": "The fine structure of freeze-fractured presynaptic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358835"}
{"pmid": "4358836", "title": "Aggregations of filaments in Schwann cells of spinal roots of the normal rat.", "content": "Aggregations of filaments in Schwann cells of spinal roots of the normal rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358836"}
{"pmid": "4358839", "title": "Editorial: Analysis of congestive heart failure in terms of ventricular function curves.", "content": "Editorial: Analysis of congestive heart failure in terms of ventricular function curves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358839"}
{"pmid": "4358840", "title": "Alcohol and the blood.", "content": "Alcohol and the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358840"}
{"pmid": "4358845", "title": "The effect of cyclic AMP and aminophylline on Limulus lateral eye retinular cells.", "content": "The effect of cyclic AMP and aminophylline on Limulus lateral eye retinular cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358845"}
{"pmid": "4358848", "title": "Effect of renal pressor systems on vascular capacity during hemorrhage.", "content": "Effect of renal pressor systems on vascular capacity during hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358848"}
{"pmid": "4358841", "title": "Respiratory characteristics of the cabbage butterfly during different stages of larval development.", "content": "Respiratory characteristics of the cabbage butterfly during different stages of larval development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358841"}
{"pmid": "4358849", "title": "Characterization of smooth muscle receptors for angiotensin: studies with an antagonist.", "content": "Characterization of smooth muscle receptors for angiotensin: studies with an antagonist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358849"}
{"pmid": "4358851", "title": "Glucose metabolism in jejunal mucosa of fed, fasted, and streptozotocin-diabetic rats.", "content": "Glucose metabolism in jejunal mucosa of fed, fasted, and streptozotocin-diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358851"}
{"pmid": "4358850", "title": "Metabolic effects of ACTH in the sheep.", "content": "Metabolic effects of ACTH in the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358850"}
{"pmid": "4358842", "title": "Cytochrome c and evolution of the energy acquiring system.", "content": "Cytochrome c and evolution of the energy acquiring system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358842"}
{"pmid": "4358853", "title": "Protocollagen proline hydroxylase activity in work-induced hypertrophy of rat muscle.", "content": "Protocollagen proline hydroxylase activity in work-induced hypertrophy of rat muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358853"}
{"pmid": "4358852", "title": "Hormonal and dietary adaptation of rat pancreatic hydrolases before and after weaning.", "content": "Hormonal and dietary adaptation of rat pancreatic hydrolases before and after weaning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358852"}
{"pmid": "4358855", "title": "Using cooperative extension programs for health education.", "content": "Using cooperative extension programs for health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358855"}
{"pmid": "4358854", "title": "Evidence for adrenocortical uptake of ACTH in vivo.", "content": "Evidence for adrenocortical uptake of ACTH in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358854"}
{"pmid": "4358856", "title": "Useful antiviral drugs.", "content": "Useful antiviral drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358856"}
{"pmid": "4358858", "title": "Use of stable, sensitized cells in indirect micro hemagglutination test for amebiasis.", "content": "Use of stable, sensitized cells in indirect micro hemagglutination test for amebiasis. Human \"O\" cells were fixed with pyruvic aldehyde, treated with tannic acid, and fixed with glutaraldehyde. The cells were sensitized with amoeba antigen and stored in a refrigerator. The sensitized cells were used periodically for the indirect hemagglutination test with a battery of sera from patients with intestinal amebiasis and confirmed and unconfirmed amebic liver abscess, and also from negative controls. The same battery was tested with cells sensitized with different batches of antigen and also with fresh sheep cells. None of the cells showed any reaction with negative control sera. The fixed cells remained sensitive and stable throughout the study. Reproducibility of the titers with the fixed cells within each day and from day to day was satisfactory. The titers with fixed human \"O\" cells were slightly lower than were the titers with fresh sheep cells. The advantages of using stable, sensitized cells are pointed out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358858"}
{"pmid": "4358857", "title": "Antibody to viruses affecting cattle in commercial tissue culture grade fetal calf serum.", "content": "Antibody to viruses affecting cattle in commercial tissue culture grade fetal calf serum. Commercial fetal calf serum (FCS) for tissue culture use was tested for neutralizing activity against several viruses which affect cattle. Certain lots of FCS contained no neutralizing activity, whereas other lots contained neutralizing activity to several viruses. It was concluded that the neutralizing activity found in certain lots of sera was due to specific antibody and that its presence could be most easily explained by the contamination of the FCS with serum from postcolostral bovine serum. A nonantibody inhibitor to vesicular stomatitis virus was also found at low levels in most lots of serum. Because those sera which had antibody had antibody to several viruses, it was suggested that the use of the micro-serum neutralization test with a few bovine viruses which are widespread in the bovine population should be satisfactory to detect FCS which was contaminated with postcolostral bovine serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358857"}
{"pmid": "4358859", "title": "Methods for visualization of enzymes in polyacrylamide gels.", "content": "Methods for visualization of enzymes in polyacrylamide gels. White bands resulting from precipitation of dodecan-1-ol liberated by hydrolysis of sodium dodecyl sulfate and decan-5-ol released by hydrolysis of decan-5-yl sulfate produced zymograms of the primary and secondary alkylsulfatases from Pseudomonas C(12)B. Gas-liquid chromatographic analyses of ether extracts of the precipitate-containing segments of the zymograms confirmed the identity of the alcohols which were not discerned in extracts of segments of the gels other than those containing precipitates. beta-Galactosidase from Escherichia coli was marked on zymograms by the liberation of o-nitrophenol from o-nitrophenyl-beta-D-galactoside, and arylsulfatase from Pseudomonas C(12)B was marked in gels by liberation of p-nitrophenol from p-nitrophenyl sulfate. Membrane-associated dissimilatory nitrate reductases from a nitrate respirer (Enterobacter aerogenes) and a denitrifier (Pseudomonas perfectomarinus) did not penetrate either 6.8 or 3% polyacrylamide gel but were demonstrable at the top of the gels. In the membrane-bound state, formate served as electron donor for nitrate reductase from E. aerogenes, and reduced nicotinamide adenine dinucleotide (NADH) served as donor for nitrate reductase from P. perfectomarinus. Both enzymes reduced nitrate at the expense of reduced benzyl viologen as well. Assimilatory nitrate reductase from E. aerogenes moved easily into the 6.8% gels (R(f) = 0.43 under the conditions of these experiments). The reduced dye served as electron donor for the assimilatory reductase, but formate and NADH did not. Incubation of the membrane-associated nitrate reductases with 2% Triton X-100 solubilized the enzymes and removed the capacity of formate and NADH to serve as electron donors. Both retained the ability to reduce nitrate at the expense of reduced benzyl viologen. The solubilized dissimilatory reductase from E. aerogenes moved further in the gels (R(f) = 0.49) than the soluble assimilatory reductase; the solubilized dissimilatory reductase from the denitrifier, P. perfectomarinus, moved further in the gels (R(f) = 0.64) than either of the enzymes from E. aerogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358859"}
{"pmid": "4358860", "title": "Detection of bacteremia with liquid media containing sodium polyanetholsulfonate.", "content": "Detection of bacteremia with liquid media containing sodium polyanetholsulfonate. Two liquid blood culture media, Tryptic soy broth (TSB) and Thiol broth, containing sodium polyanetholsulfonate were compared in 8,654 cultures. Pseudomonas and Corynebacterium (including Propionibacterium) were isolated significantly more frequently (P < 0.001) from TSB than from Thiol. Escherichia coli, Haemophilus, and Bacteroidaceae were isolated more frequently in TSB; however, the differences were not statistically significant. In no instance was Thiol superior to TSB in detecting bacteremia. In an additional 2,977 cultures, aerobic and anaerobic Vacutainer culture tubes with supplemented peptone broth were inoculated in parallel with TSB and Thiol. Significantly greater rates of detection (P < 0.01) in TSB or Thiol were noted with Pseudomonas, E. coli, Enterobacter, viridans, and group A streptococci, Bacteroidaceae, and staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358860"}
{"pmid": "4358861", "title": "Microtiter hemagglutination-inhibition test for the detection of encephalomyocarditis virus antibodies.", "content": "Microtiter hemagglutination-inhibition test for the detection of encephalomyocarditis virus antibodies. Several variables were found to affect the agglutination of sheep erythrocytes by encephalomyocarditis virus. A satisfactory and reliable microtiter hemagglutination-inhibition test is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358861"}
{"pmid": "4358863", "title": "Evaluation and modifications of media for enumeration of Clostridium perfringens.", "content": "Evaluation and modifications of media for enumeration of Clostridium perfringens. The suitability of the Shahidi-Ferguson perfringens, TSC (tryptose-sulfite-cycloserine), and oleandomycin-polymyxin-sulfadiazine perfringens agars for presumptive enumeration of Clostridium perfringens was tested. Of these, the TSC agar was the most satisfactory. The TSC agar method was improved by eliminating the egg yolk and using pour plates. The modified method allowed quantitative recoveries of each of 71 C. perfringens strains tested and is recommended. For confirmation of C. perfringens, the nitrite test in nitrate motility agar was unreliable, particularly after storage of the medium for a few days. In contrast, positive nitrite reactions were obtained consistently when nitrate motility agar was supplemented with glycerol and galactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358863"}
{"pmid": "4358862", "title": "Inactivation of encephalomyocarditis virus in aerosols: fate of virus protein and ribonucleic acid.", "content": "Inactivation of encephalomyocarditis virus in aerosols: fate of virus protein and ribonucleic acid. After aerosolization at relative humidities of 50% or lower, encephalomyocarditis virus is rapidly inactivated. In this process the protein coat of the virion is damaged. This appears as a loss of hemagglutination activity and loss of affinity for hemagglutination inhibiting antibodies. The ribonucleic acid of the virus retains its infectivity but it becomes susceptible to ribonuclease. It sediments in sucrose gradients when centrifuged at high speed with the same velocity as free infectious ribonucleic acid extracted with phenol from intact encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358862"}
{"pmid": "4358864", "title": "A follow-up of monozygotic twins discordant for schizophrenia.", "content": "A follow-up of monozygotic twins discordant for schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358864"}
{"pmid": "4358865", "title": "Basal cell adenoma of the parotid gland.", "content": "Basal cell adenoma of the parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358865"}
{"pmid": "4358866", "title": "Intramitochondrial filamentous inclusions in chronic glomerulonephritis.", "content": "Intramitochondrial filamentous inclusions in chronic glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358866"}
{"pmid": "4358867", "title": "Mallory bodies and giant mitochondria--two different structures in liver biopies from alcoholics.", "content": "Mallory bodies and giant mitochondria--two different structures in liver biopies from alcoholics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358867"}
{"pmid": "4358868", "title": "The mechanism of action of the respiratory inhibitor, antimycin.", "content": "The mechanism of action of the respiratory inhibitor, antimycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358868"}
{"pmid": "4358869", "title": "The different cytochrome b components in the respiratory chain of animal mitochondria and their role in electron transport and energy conservation.", "content": "The different cytochrome b components in the respiratory chain of animal mitochondria and their role in electron transport and energy conservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358869"}
{"pmid": "4358870", "title": "Odontodysplasia.", "content": "Odontodysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358870"}
{"pmid": "4358871", "title": "Oral medicine for the dental practitioner. 4. Recurrent ulcers.", "content": "Oral medicine for the dental practitioner. 4. Recurrent ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358871"}
{"pmid": "4358873", "title": "The separation of human B lymphocytes on a digestible immunoadsorbent column.", "content": "The separation of human B lymphocytes on a digestible immunoadsorbent column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358873"}
{"pmid": "4358874", "title": "Operative and cytostatic treatment of germinal tumours of the testis.", "content": "Operative and cytostatic treatment of germinal tumours of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358874"}
{"pmid": "4358876", "title": "Phospholipids in the cytochrome oxidase reaction.", "content": "Phospholipids in the cytochrome oxidase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358876"}
{"pmid": "4358878", "title": "Effect of estrogens on the mast cell degranulating action of compound 48-80.", "content": "Effect of estrogens on the mast cell degranulating action of compound 48-80.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358878"}
{"pmid": "4358877", "title": "Sulfhydryl groups of cytochrome oxidase.", "content": "Sulfhydryl groups of cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358877"}
{"pmid": "4358879", "title": "Selective cytotoxicity of peritoneal leucocytes. A preliminary report.", "content": "Selective cytotoxicity of peritoneal leucocytes. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358879"}
{"pmid": "4358880", "title": "Some properties of a homocarnosine-carnosine synthetase isolated from rat brain.", "content": "Some properties of a homocarnosine-carnosine synthetase isolated from rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358880"}
{"pmid": "4358881", "title": "Electrophoretic characterization of leucine, glucosamine- and fucose-labelled proteins rapidly transported in frog sciatic nerve.", "content": "Electrophoretic characterization of leucine, glucosamine- and fucose-labelled proteins rapidly transported in frog sciatic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358881"}
{"pmid": "4358882", "title": "Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence.", "content": "Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358882"}
{"pmid": "4358884", "title": "Editorial: Insomnia.", "content": "Editorial: Insomnia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358884"}
{"pmid": "4358883", "title": "Massive hyperlipemia during estrogen therapy.", "content": "Massive hyperlipemia during estrogen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358883"}
{"pmid": "4358887", "title": "Avian leukosis-sarcoma virus antibodies in wildfowl, domestic chickens and man in Kenya.", "content": "Avian leukosis-sarcoma virus antibodies in wildfowl, domestic chickens and man in Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358887"}
{"pmid": "4358875", "title": "Measurement of human red cell angiotensinase activity by angiotensin II radioimmunoassay.", "content": "Measurement of human red cell angiotensinase activity by angiotensin II radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358875"}
{"pmid": "4358888", "title": "Activation of type C RNA tumor virus expressions in tumors induced by cell cultures transformed by polyoma virus.", "content": "Activation of type C RNA tumor virus expressions in tumors induced by cell cultures transformed by polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358888"}
{"pmid": "4358889", "title": "Neutralizing antibody against infectious canine hepatitis virus (ICHV) in veterinary workers' sera.", "content": "Neutralizing antibody against infectious canine hepatitis virus (ICHV) in veterinary workers' sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358889"}
{"pmid": "4358890", "title": "Effect of sex and sex hormones on plasma prothrombin and vitamin K deficiency.", "content": "Effect of sex and sex hormones on plasma prothrombin and vitamin K deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358890"}
{"pmid": "4358891", "title": "Spontaneous in vitro transformation of leukocytes from a neonate.", "content": "Spontaneous in vitro transformation of leukocytes from a neonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358891"}
{"pmid": "4358893", "title": "Cytochalasin D enhances infectivity of poliovirus.", "content": "Cytochalasin D enhances infectivity of poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358893"}
{"pmid": "4358892", "title": "The growth of varicella-zoster virus in guinea pig embryo cells.", "content": "The growth of varicella-zoster virus in guinea pig embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358892"}
{"pmid": "4358895", "title": "Remarks on mammographic calcifications.", "content": "Remarks on mammographic calcifications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358895"}
{"pmid": "4358894", "title": "Effects of corticosterone on phosphorylation of rat liver nuclear proteins in vitro.", "content": "Effects of corticosterone on phosphorylation of rat liver nuclear proteins in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358894"}
{"pmid": "4358896", "title": "Kinetics of the phenotypic expression of mutations for streptomycin resistance induced by methylmethane sulfonate, N-methyl-N'-nitro-N-nitrosoguanidine, and ultraviolet light in Escherichia coli K-12.", "content": "Kinetics of the phenotypic expression of mutations for streptomycin resistance induced by methylmethane sulfonate, N-methyl-N'-nitro-N-nitrosoguanidine, and ultraviolet light in Escherichia coli K-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358896"}
{"pmid": "4358897", "title": "Cytogenetic effect of alkylating mutagens as a function of the physiological state of seeds.", "content": "Cytogenetic effect of alkylating mutagens as a function of the physiological state of seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358897"}
{"pmid": "4358899", "title": "Renal trauma and preexisting lesions of kidney.", "content": "Renal trauma and preexisting lesions of kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358899"}
{"pmid": "4358902", "title": "Products of mitochondrial protein synthesis.", "content": "Products of mitochondrial protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358902"}
{"pmid": "4358905", "title": "In vitro effects of prolactin and cortisol on water permeability of the urinary bladder of the teleost Gillichthys mirabilis.", "content": "In vitro effects of prolactin and cortisol on water permeability of the urinary bladder of the teleost Gillichthys mirabilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358905"}
{"pmid": "4358904", "title": "Ultrastructural effects of dark-adaptation on eyes of a snail, Helix aspersa.", "content": "Ultrastructural effects of dark-adaptation on eyes of a snail, Helix aspersa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358904"}
{"pmid": "4358907", "title": "What is your diagnosis? Mixed tumor.", "content": "What is your diagnosis? Mixed tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358907"}
{"pmid": "4358906", "title": "Cleavage initiating activities of sperm fractions injected into the egg of the medaka, Oryzias latipes.", "content": "Cleavage initiating activities of sperm fractions injected into the egg of the medaka, Oryzias latipes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358906"}
{"pmid": "4358909", "title": "Statewide policies for planning nursing education in Minnesota.", "content": "Statewide policies for planning nursing education in Minnesota.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358909"}
{"pmid": "4358908", "title": "An investigation of hydrolytic techniques for the amino acid analysis of foodstuffs.", "content": "An investigation of hydrolytic techniques for the amino acid analysis of foodstuffs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358908"}
{"pmid": "4358910", "title": "Dopamine-induced inhibition of synaptic transmission in lumbar paravertebral ganglia of the dog.", "content": "Dopamine-induced inhibition of synaptic transmission in lumbar paravertebral ganglia of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358910"}
{"pmid": "4358912", "title": "Effect of vasopressin administration on renal haemodynamic changes in rats treated with ACTH.", "content": "Effect of vasopressin administration on renal haemodynamic changes in rats treated with ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358912"}
{"pmid": "4358914", "title": "Primary herpetic gingivostomatitis in the adult.", "content": "Primary herpetic gingivostomatitis in the adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358914"}
{"pmid": "4358913", "title": "The action of unconjugated bilirubin on some enzyme activities of in vitro cultured cells.", "content": "The action of unconjugated bilirubin on some enzyme activities of in vitro cultured cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358913"}
{"pmid": "4358915", "title": "Intraneuronal lipid droplets in irradiated nervous tissue.", "content": "Intraneuronal lipid droplets in irradiated nervous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358915"}
{"pmid": "4358917", "title": "Ultrastructure of the protein containing vacuoles and hyaline droplets in rat adrenocortical cells following polybrene.", "content": "Ultrastructure of the protein containing vacuoles and hyaline droplets in rat adrenocortical cells following polybrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358917"}
{"pmid": "4358923", "title": "Acute renal failure in obstetrics.", "content": "Acute renal failure in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358923"}
{"pmid": "4358922", "title": "Action of metabolic hormones on the fine structure of liver cells. II. Effects of hypophysectomy and chronic administration of somatotropin.", "content": "Action of metabolic hormones on the fine structure of liver cells. II. Effects of hypophysectomy and chronic administration of somatotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358922"}
{"pmid": "4358925", "title": "Malignant epithelial tumors of the parotid gland. Classification, staging and treatment.", "content": "Malignant epithelial tumors of the parotid gland. Classification, staging and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358925"}
{"pmid": "4358924", "title": "Immunologic response in gynecologic malignancy as demonstrated by the delayed hypersensitivity reaction: clinical correlations.", "content": "Immunologic response in gynecologic malignancy as demonstrated by the delayed hypersensitivity reaction: clinical correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358924"}
{"pmid": "4358921", "title": "Karyotypic variation in benign pleomorphic adenoma of the parotid and in normal salivary glands.", "content": "Karyotypic variation in benign pleomorphic adenoma of the parotid and in normal salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358921"}
{"pmid": "4358926", "title": "Studies on the combined action of antibiotics on Pseudomonas aeruginosa strains.", "content": "Studies on the combined action of antibiotics on Pseudomonas aeruginosa strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358926"}
{"pmid": "4358927", "title": "Studies on neutral esters of cyclic AMP.", "content": "Studies on neutral esters of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358927"}
{"pmid": "4358928", "title": "Independence of theta and TL surface antigens and killing by thymidine, cortisol, phytohemagglutinin, and cyclic AMP in a murine lymphoma.", "content": "Independence of theta and TL surface antigens and killing by thymidine, cortisol, phytohemagglutinin, and cyclic AMP in a murine lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358928"}
{"pmid": "4358929", "title": "Nucleotide sequence analysis of DNA. XII. The chemical synthesis and sequence analysis of a dodecadeoxynucleotide which binds to the endolysin gene of bacteriophage lambda.", "content": "Nucleotide sequence analysis of DNA. XII. The chemical synthesis and sequence analysis of a dodecadeoxynucleotide which binds to the endolysin gene of bacteriophage lambda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358929"}
{"pmid": "4358931", "title": "Binding of trifluorolactate to pig heart H4-lactate dehydrogenase.", "content": "Binding of trifluorolactate to pig heart H4-lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358931"}
{"pmid": "4358930", "title": "Some properties of coupled hepatoma mitochondria exhibiting uncoupler-insensitive ATPase activity.", "content": "Some properties of coupled hepatoma mitochondria exhibiting uncoupler-insensitive ATPase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358930"}
{"pmid": "4358919", "title": "Biochemical studies of otosclerosis. Phosphohydrolase activity in stapedial footplates.", "content": "Biochemical studies of otosclerosis. Phosphohydrolase activity in stapedial footplates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358919"}
{"pmid": "4358932", "title": "Analysis of amino acid phenylthiohydantoins by high speed liquid chromatography.", "content": "Analysis of amino acid phenylthiohydantoins by high speed liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358932"}
{"pmid": "4358933", "title": "Alteration of NAD-linked malic enzyme-catalyzed reactions by sulfhydryl group modification.", "content": "Alteration of NAD-linked malic enzyme-catalyzed reactions by sulfhydryl group modification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358933"}
{"pmid": "4358935", "title": "Model reactions for the study of the interaction of sulfur dioxide with mammalian organisms.", "content": "Model reactions for the study of the interaction of sulfur dioxide with mammalian organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358935"}
{"pmid": "4358934", "title": "Carbamylphosphate synthetase of lactating bovine mammary tissue.", "content": "Carbamylphosphate synthetase of lactating bovine mammary tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358934"}
{"pmid": "4358937", "title": "A specific spin labeling of the anticodon of E. coli tRNA-Glu.", "content": "A specific spin labeling of the anticodon of E. coli tRNA-Glu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358937"}
{"pmid": "4358936", "title": "Cyclic AMP phosphodiesterase activation by the histamine releasing agent, compound 48-80.", "content": "Cyclic AMP phosphodiesterase activation by the histamine releasing agent, compound 48-80.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358936"}
{"pmid": "4358938", "title": "Polychlorinated biphenyls: hydroxylated urinary metabolites of 2,5,2',5'-tetrachlorobiphenyl identified in rabbits.", "content": "Polychlorinated biphenyls: hydroxylated urinary metabolites of 2,5,2',5'-tetrachlorobiphenyl identified in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358938"}
{"pmid": "4358939", "title": "Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins.", "content": "Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358939"}
{"pmid": "4358940", "title": "Prediction of protein conformation.", "content": "Prediction of protein conformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358940"}
{"pmid": "4358942", "title": "Estrogen receptor binding to isolated nuclei. A nonsaturable process.", "content": "Estrogen receptor binding to isolated nuclei. A nonsaturable process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358942"}
{"pmid": "4358941", "title": "Changes in sulfhydryl groups of honeybee glyceraldehyde phosphate dehydrogenase associated with generation of the intermediate plateau in its saturation kinetics.", "content": "Changes in sulfhydryl groups of honeybee glyceraldehyde phosphate dehydrogenase associated with generation of the intermediate plateau in its saturation kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358941"}
{"pmid": "4358943", "title": "Glucocorticoid receptors in mouse pituitary tumor cells. II. Nuclear binding.", "content": "Glucocorticoid receptors in mouse pituitary tumor cells. II. Nuclear binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358943"}
{"pmid": "4358945", "title": "Monomeric and dimeric forms of component II of the anthranilate synthetase--anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase complex of Salmonella typhimurium. Implications concerning the mode of assembly of the complex.", "content": "Monomeric and dimeric forms of component II of the anthranilate synthetase--anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase complex of Salmonella typhimurium. Implications concerning the mode of assembly of the complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358945"}
{"pmid": "4358944", "title": "The dynamic structure of lipid membranes. A 13C nuclear magnetic resonance study using spin labels.", "content": "The dynamic structure of lipid membranes. A 13C nuclear magnetic resonance study using spin labels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358944"}
{"pmid": "4358946", "title": "Substrate-attached glycoproteins from normal and virus-transformed cells.", "content": "Substrate-attached glycoproteins from normal and virus-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358946"}
{"pmid": "4358947", "title": "Structure and activity of methylated horse liver alcohol dehydrogenase.", "content": "Structure and activity of methylated horse liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358947"}
{"pmid": "4358949", "title": "Physical identity of the SV40 deoxyribonucleic acid sequence recognized by the Eco RI restriction endonuclease and modification methylase.", "content": "Physical identity of the SV40 deoxyribonucleic acid sequence recognized by the Eco RI restriction endonuclease and modification methylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358949"}
{"pmid": "4358948", "title": "A filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrant.", "content": "A filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358948"}
{"pmid": "4358951", "title": "Human placental tryptophanyl transfer ribonucleic acid synthetase. Purification and subunit structure.", "content": "Human placental tryptophanyl transfer ribonucleic acid synthetase. Purification and subunit structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358951"}
{"pmid": "4358950", "title": "Derivatives of N-(N-(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl)threonine in phosphodiesterase hydrolysates of wheat embryo transfer ribonucleic acid.", "content": "Derivatives of N-(N-(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl)threonine in phosphodiesterase hydrolysates of wheat embryo transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358950"}
{"pmid": "4358953", "title": "Malignant fibrous histiocytoma with widespread metastases. Autopsy study.", "content": "Malignant fibrous histiocytoma with widespread metastases. Autopsy study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358953"}
{"pmid": "4358952", "title": "Human tryptophanyl transfer ribonucleic acid synthetase. Comparison of the kinetic mechanism to that of the Escherichia coli tryptophanyl transfer ribonucleic acid synthetase.", "content": "Human tryptophanyl transfer ribonucleic acid synthetase. Comparison of the kinetic mechanism to that of the Escherichia coli tryptophanyl transfer ribonucleic acid synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358952"}
{"pmid": "4358954", "title": "Mucinous adenocarcinoma of the renal pelvis. Report of two cases.", "content": "Mucinous adenocarcinoma of the renal pelvis. Report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358954"}
{"pmid": "4358955", "title": "Elastosis in breast cancer.", "content": "Elastosis in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358955"}
{"pmid": "4358956", "title": "Familial arrhenoblastoma and thyroid adenoma.", "content": "Familial arrhenoblastoma and thyroid adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358956"}
{"pmid": "4358957", "title": "Malignant chemodectoma presenting as a miliary pulmonary infiltrate.", "content": "Malignant chemodectoma presenting as a miliary pulmonary infiltrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358957"}
{"pmid": "4358959", "title": "Studies on the quaternary structure of the first enzyme for histidine biosynthesis.", "content": "Studies on the quaternary structure of the first enzyme for histidine biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358959"}
{"pmid": "4358960", "title": "On the mechanism of the inhibitory action of 2-amino-4,6-dichloropyrimidine on poliovirus growth.", "content": "On the mechanism of the inhibitory action of 2-amino-4,6-dichloropyrimidine on poliovirus growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358960"}
{"pmid": "4358961", "title": "Irreversible impairment produced by guanidine on the functions of poliovirus proteins.", "content": "Irreversible impairment produced by guanidine on the functions of poliovirus proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358961"}
{"pmid": "4358962", "title": "Morphological and enzymehistochemical changes in the interscapular adipose tissue of adult guinea-pigs during prolonged exposure to cold.", "content": "Morphological and enzymehistochemical changes in the interscapular adipose tissue of adult guinea-pigs during prolonged exposure to cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358962"}
{"pmid": "4358963", "title": "Localization of genes on human chromosomes by studies of human-Chinese hamster somatic cell hybrids. Assignment of PGM3 to chromosome C6 and regional mapping of the PGD, PGM1 and pep-C genes on chromosome A1.", "content": "Localization of genes on human chromosomes by studies of human-Chinese hamster somatic cell hybrids. Assignment of PGM3 to chromosome C6 and regional mapping of the PGD, PGM1 and pep-C genes on chromosome A1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358963"}
{"pmid": "4358964", "title": "Chromosome assignments of genes in man using mouse-human somatic cell hybrids: mitochondrial superoxide dismutase (indophenol oxidase-B, tetrameric) to chromosome 6.", "content": "Chromosome assignments of genes in man using mouse-human somatic cell hybrids: mitochondrial superoxide dismutase (indophenol oxidase-B, tetrameric) to chromosome 6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358964"}
{"pmid": "4358965", "title": "Syrian hamster-human somatic cell hybrids: isolation and characterization.", "content": "Syrian hamster-human somatic cell hybrids: isolation and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358965"}
{"pmid": "4358968", "title": "Long-term storage, migration and elimination of dust in the lungs of animals, with special respect to the influence of polyvinyl-pyridine-N-oxide.", "content": "Long-term storage, migration and elimination of dust in the lungs of animals, with special respect to the influence of polyvinyl-pyridine-N-oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358968"}
{"pmid": "4358969", "title": "Influence of BCG on lymphatic lung clearance in rats.", "content": "Influence of BCG on lymphatic lung clearance in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358969"}
{"pmid": "4358970", "title": "The relationship between duration of dust inhalation of a coal-quartz mixture and dust retention, lung function and pathology on rats.", "content": "The relationship between duration of dust inhalation of a coal-quartz mixture and dust retention, lung function and pathology on rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358970"}
{"pmid": "4358971", "title": "Lung function studies in experimental silicosis with a radiospirometric technique and some observations on a technique for inducing unilateral silicosis. A preliminary report.", "content": "Lung function studies in experimental silicosis with a radiospirometric technique and some observations on a technique for inducing unilateral silicosis. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358971"}
{"pmid": "4358972", "title": "Observations on the mechanism of silicotic fibrogenesis.", "content": "Observations on the mechanism of silicotic fibrogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358972"}
{"pmid": "4358973", "title": "Investigations on the aetiology of coal workers' pneumoconiosis with the use of PVN-oxide.", "content": "Investigations on the aetiology of coal workers' pneumoconiosis with the use of PVN-oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358973"}
{"pmid": "4358975", "title": "On the cell toxicity of mineral dusts.", "content": "On the cell toxicity of mineral dusts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358975"}
{"pmid": "4358977", "title": "The cytotoxic action and the semiconductor properties of mine dusts.", "content": "The cytotoxic action and the semiconductor properties of mine dusts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358977"}
{"pmid": "4358978", "title": "The role of some physical and chemical properties of mine dust in the development of pneumoconiosis.", "content": "The role of some physical and chemical properties of mine dust in the development of pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358978"}
{"pmid": "4358979", "title": "Post-hospital discharge: patient care and utilization of services and facilities.", "content": "Post-hospital discharge: patient care and utilization of services and facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358979"}
{"pmid": "4358980", "title": "\"The central areas\" of denervated canine muscle.", "content": "\"The central areas\" of denervated canine muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358980"}
{"pmid": "4358981", "title": "Pathology of Clostridium welchii type D enterotoxaemia. I. Biochemical and haematological alterations in lambs.", "content": "Pathology of Clostridium welchii type D enterotoxaemia. I. Biochemical and haematological alterations in lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358981"}
{"pmid": "4358982", "title": "Pathology of Clostridium welchii type D enterotoxaemia. II. Structural and ultrastructural alterations in the tissues of lambs and mice.", "content": "Pathology of Clostridium welchii type D enterotoxaemia. II. Structural and ultrastructural alterations in the tissues of lambs and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358982"}
{"pmid": "4358984", "title": "Spontaneous malignant neoplasms in dasyurid marsupials.", "content": "Spontaneous malignant neoplasms in dasyurid marsupials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358984"}
{"pmid": "4358983", "title": "Pathology of Clostridium welchii type D enterotoxaemia. 3. Basis of the hyperglycaemic response.", "content": "Pathology of Clostridium welchii type D enterotoxaemia. 3. Basis of the hyperglycaemic response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358983"}
{"pmid": "4358985", "title": "Pulmonary adenomatosis in ageing mice.", "content": "Pulmonary adenomatosis in ageing mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358985"}
{"pmid": "4358986", "title": "Terminal oxidases and carbon monoxide-reacting haemoproteins in the trypanosomatid, Crithidia fasciculata.", "content": "Terminal oxidases and carbon monoxide-reacting haemoproteins in the trypanosomatid, Crithidia fasciculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358986"}
{"pmid": "4358987", "title": "Chemistry of the filaments and tubules of brain.", "content": "Chemistry of the filaments and tubules of brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358987"}
{"pmid": "4358988", "title": "Electronystagmographic comparison of acute idiopathic and herpes zoster facial paralysis.", "content": "Electronystagmographic comparison of acute idiopathic and herpes zoster facial paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358988"}
{"pmid": "4358989", "title": "Letter: Gas gangrene.", "content": "Letter: Gas gangrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358989"}
{"pmid": "4358993", "title": "Letter: Potassium, aldosterone and renin inter-relations.", "content": "Letter: Potassium, aldosterone and renin inter-relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358993"}
{"pmid": "4358992", "title": "Fatal infectious mononucleosis in a family.", "content": "Fatal infectious mononucleosis in a family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358992"}
{"pmid": "4358994", "title": "Depolarization generated by acetylcholine through activation of triphosphoinositide phosphomonoesterase.", "content": "Depolarization generated by acetylcholine through activation of triphosphoinositide phosphomonoesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358994"}
{"pmid": "4358998", "title": "Physostigmine in choreiform movement disorders.", "content": "Physostigmine in choreiform movement disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358998"}
{"pmid": "4358999", "title": "Evaluation of antithymocyte globulin in acute relapses of multiple sclerosis.", "content": "Evaluation of antithymocyte globulin in acute relapses of multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4358999"}
{"pmid": "4359000", "title": "An experimental myopathy secondary to excessive acetylcholine release.", "content": "An experimental myopathy secondary to excessive acetylcholine release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359000"}
{"pmid": "4359001", "title": "Automatic midline echoencephalography. Examination of 3,333 consecutive cases with the automatic midline computer.", "content": "Automatic midline echoencephalography. Examination of 3,333 consecutive cases with the automatic midline computer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359001"}
{"pmid": "4359002", "title": "A natriuresis receptor at the carotid bifurcation specifically activated by oxytocin.", "content": "A natriuresis receptor at the carotid bifurcation specifically activated by oxytocin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359002"}
{"pmid": "4359003", "title": "A new model for transmitter mobilization in the frog neuromuscular junction.", "content": "A new model for transmitter mobilization in the frog neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359003"}
{"pmid": "4359005", "title": "Angiographic findings in benign liver cell tumors.", "content": "Angiographic findings in benign liver cell tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359005"}
{"pmid": "4359006", "title": "A complication of skin testing with iodinated radiographic contrast medium.", "content": "A complication of skin testing with iodinated radiographic contrast medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359006"}
{"pmid": "4359007", "title": "Total body radionuclide localization in infants.", "content": "Total body radionuclide localization in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359007"}
{"pmid": "4359008", "title": "A new method for radionuclide imaging of myocardial infarcts.", "content": "A new method for radionuclide imaging of myocardial infarcts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359008"}
{"pmid": "4359009", "title": "Pediatric urology.", "content": "Pediatric urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359009"}
{"pmid": "4359016", "title": "Pharmacokinetics and dosing of antimicrobial agents in renal impairment. I.", "content": "Pharmacokinetics and dosing of antimicrobial agents in renal impairment. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359016"}
{"pmid": "4359018", "title": "N-acetyl-beta-D-hexosaminidase component A. Different forms in human tissues and fluids.", "content": "N-acetyl-beta-D-hexosaminidase component A. Different forms in human tissues and fluids. 1. Hexosaminidase A of human serum was resolved into two components, a minor form with properties identical with those of the single hexosaminidase A component of human liver, and a major form with significantly different properties. 2. The major serum hexosaminidase A form was eluted from a DEAE-cellulose column at a lower salt concentration than that required to elute the liver form. 3. A multiple-pass technique was used to elute the major serum enzyme A from a Sephadex G-150 column before that of liver enzyme A. 4. Clostridium perfringens neuraminidase converted the major component of serum hexosaminidase A into a form that was held less tightly by DEAE-cellulose, but the minor component of the A enzyme of serum, and the A enzyme of liver were not affected. 5. The hexosaminidase A from tears was similar to the A enzyme from serum, whereas those from several human tissues and from urine and lymph were similar to the liver form. 6. The A enzyme from serum may be derived from the A enzyme from liver by glycosylation before secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359018"}
{"pmid": "4359017", "title": "Collagen cross-linking. Isolation of cross-linked peptides from collagen of chicken bone.", "content": "Collagen cross-linking. Isolation of cross-linked peptides from collagen of chicken bone. Cross-linked peptides were isolated from chicken bone collagen that had been digested with CNBr or with bacterial collagenase. Analyses of (3)H radioactivity in disc electrophoretic profiles of the CNBr peptides from bone collagens that had been treated with NaB(3)H indicated that a major site of intermolecular cross-linking in chicken bone collagen is located between the carboxy-terminal region of an alpha1 chain and a small CNBr peptide, probably situated near the amino-terminus of an alpha1 or alpha2 chain in an adjacent collagen molecule. A small amount of this cross-linked CNBr peptide was isolated from a CNBr digest of chicken bone collagen by column chromatography. Amino acid analysis showed that the CNBr peptide, alpha1CB6B, the carboxy-terminal peptide of the alpha1 chain, was the major CNBr peptide in the preparation, and the reduced cross-linking components were identified as hydroxylysinohydroxynorleucine (HylOHNle), with a smaller amount of hydroxylysinonorleucine (HylNle). However, the composition and the low recovery of the cross-linking amino acids suggested that the preparation was a mixture of CNBr peptides alpha1CB6B and alpha1CB6B cross-linked to a small CNBr peptide whose identity could not be determined. A small cross-linked peptide was isolated from chicken bone collagen that had been reduced with NaB(3)H(4) and digested with bacterial collagenase. This peptide was the major cross-linked peptide in the digest and contained a stoicheiometric amount of the reduced cross-linking compounds. A peptide which had the same amino acid composition, but contained the cross-linking compounds in their reducible forms, was isolated from a collagenase digest of chicken bone collagen that had not been treated with NaBH(4). The absence of the reduced cross-links from this peptide indicates that, at least for the cross-linking site from which the peptide derives, natural reduction is not a significant pathway for biosynthesis of stable cross-links. However, most of the reducible cross-linking component in the peptide appeared to stabilize in the bone collagen by rearrangement from aldimine to ketoamine form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359017"}
{"pmid": "4359019", "title": "Functional groups in the activity and regulation of Escherichia coli citrate synthase.", "content": "Functional groups in the activity and regulation of Escherichia coli citrate synthase. 1. Citrate synthase has been purified from Escherichia coli and shown to exist at an equilibrium between three forms: monomer (mol.wt. 57000), tetramer (mol.wt. 230000) and, possibly, octamer. Modification of the enzyme by photo-oxidation and by treatment with specific chemical reagents has been carried out to gain information on the amino acid residues involved in enzymic activity and in the inhibition of activity by NADH and alpha-oxoglutarate. 2. Several photo-oxidizable amino acids appear to be involved in activity. The nature of the pH-dependence of their rates of photo-oxidation with Methylene Blue suggests that these are histidines, a conclusion supported by the greater rate of photo-inactivation with Rose Bengal and the destruction of activity by diethyl pyrocarbonate. 3. The participation of histidine at the alpha-oxoglutarate effector site is indicated by photo-oxidation and the participation of cysteine at the NADH effector site suggested by photo-oxidation is confirmed by the desensitization to NADH produced by treatment with 5,5'-dithiobis-(2-nitrobenzoate). Inactivation of the enzyme after modification with this reagent suggests the additional involvement of cysteine in catalytic activity. 4. Amino acid analyses of native and photo-oxidized enzyme are consistent with these conclusions. 5. Modification with 2-hydroxy-5-nitrobenzyl bromide indicates the participation of tryptophan in the activity of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359019"}
{"pmid": "4359020", "title": "The use of sodium perchlorate in deproteinization during the preparation of nucleic acids.", "content": "The use of sodium perchlorate in deproteinization during the preparation of nucleic acids. Sodium perchlorate in high concentrations will remove from solution the detergent sodium dodecyl sulphate and protein complexed with it. This and the failure of proteins to be precipitated by ethanol from solutions containing a high concentration of sodium perchlorate can be utilized as efficient, rapid and simple deproteinization procedures during the preparation of nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359020"}
{"pmid": "4359021", "title": "Phosphorylation of myelin basic protein by an adenosine 3':5'-cyclic monophosphate-dependent protein kinase.", "content": "Phosphorylation of myelin basic protein by an adenosine 3':5'-cyclic monophosphate-dependent protein kinase. Myelin basic protein was shown to be a substrate for protein kinase from rabbit muscle. One of the major sites of phosphorylation was the serine residue in the sequence Gly-Arg-Gly-Leu-Ser-Leu. The arginine residue in this sequence is known to be a substrate for a protein methylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359021"}
{"pmid": "4359022", "title": "Structural investigations of lipid, polypeptide and protein multilayers.", "content": "Structural investigations of lipid, polypeptide and protein multilayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359022"}
{"pmid": "4359024", "title": "The high molecular weight RNA of Visna virus.", "content": "The high molecular weight RNA of Visna virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359024"}
{"pmid": "4359026", "title": "Strychnine interactions with acetylcholine, dopamine and serotonin receptors in Aplysia neurons.", "content": "Strychnine interactions with acetylcholine, dopamine and serotonin receptors in Aplysia neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359026"}
{"pmid": "4359028", "title": "Attention of transmission through glomeruli of olfactory bulb on paired shock stimulation.", "content": "Attention of transmission through glomeruli of olfactory bulb on paired shock stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359028"}
{"pmid": "4359029", "title": "Relation of glomerular neuronal activity to glomerular transmission attenuation.", "content": "Relation of glomerular neuronal activity to glomerular transmission attenuation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359029"}
{"pmid": "4359030", "title": "The synthesis of p-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl) P2-ficaprenyl pyrophosphate.", "content": "The synthesis of p-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl) P2-ficaprenyl pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359030"}
{"pmid": "4359031", "title": "Angiography of renal capsular complex in normal and pathological conditions and its diagnostic implications.", "content": "Angiography of renal capsular complex in normal and pathological conditions and its diagnostic implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359031"}
{"pmid": "4359032", "title": "Vasodilator reserve, parallel vascular beds, and significant stenosis: a review for the angiographer.", "content": "Vasodilator reserve, parallel vascular beds, and significant stenosis: a review for the angiographer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359032"}
{"pmid": "4359033", "title": "The therapeutic effects of cyclacillin in acute sinusitis: in vitro and in vivo correlations in a placebo-controlled study.", "content": "The therapeutic effects of cyclacillin in acute sinusitis: in vitro and in vivo correlations in a placebo-controlled study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359033"}
{"pmid": "4359034", "title": "The acute effect of tetracosactrin on carbohydrate, insulin, glucagon, gastrin and lipid metabolism in rheumatoid arthritis.", "content": "The acute effect of tetracosactrin on carbohydrate, insulin, glucagon, gastrin and lipid metabolism in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359034"}
{"pmid": "4359036", "title": "Inhibition of phosphorylase-a by fructose-1-phosphate, alpha-glycerophosphate and fructose-1,6-diphosphate: explanation for fructose-induced hypoglycaemia in hereditary fructose intolerance and fructose-1,6-diphosphatase deficiency.", "content": "Inhibition of phosphorylase-a by fructose-1-phosphate, alpha-glycerophosphate and fructose-1,6-diphosphate: explanation for fructose-induced hypoglycaemia in hereditary fructose intolerance and fructose-1,6-diphosphatase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359036"}
{"pmid": "4359035", "title": "The induction of fibrogenesis by silica-treated alveolar macrophages.", "content": "The induction of fibrogenesis by silica-treated alveolar macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359035"}
{"pmid": "4359037", "title": "Prostaglandins and renal function.", "content": "Prostaglandins and renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359037"}
{"pmid": "4359038", "title": "Prostaglandins as modulators of the autonomic nervous system.", "content": "Prostaglandins as modulators of the autonomic nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359038"}
{"pmid": "4359039", "title": "Prostaglandins and the thyroid gland.", "content": "Prostaglandins and the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359039"}
{"pmid": "4359040", "title": "Ultrastructural observations on human oocytes fertilized in vitro.", "content": "Ultrastructural observations on human oocytes fertilized in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359040"}
{"pmid": "4359060", "title": "A rapid screening procedure for some \"street-drugs\" by thin-layer chromatography. II. Cocaine, heroin, local anesthetics and mixtures.", "content": "A rapid screening procedure for some \"street-drugs\" by thin-layer chromatography. II. Cocaine, heroin, local anesthetics and mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359060"}
{"pmid": "4359061", "title": "Separation of diphosphoinositide and triphosphoinositide on oxalate-impregnated silica gel columns.", "content": "Separation of diphosphoinositide and triphosphoinositide on oxalate-impregnated silica gel columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359061"}
{"pmid": "4359062", "title": "Intraoperaoperative echoencephalography.", "content": "Intraoperaoperative echoencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359062"}
{"pmid": "4359063", "title": "Control of retinal sensitivity. I. Light and dark adaptation of vertebrate rods and cones.", "content": "Control of retinal sensitivity. I. Light and dark adaptation of vertebrate rods and cones. Rods and cones in Necturus respond with graded hyperpolarization to test flashes spanning about 3.5 log units of intensity. Steady background levels hyperpolarize the rods, and the rod responses become progressively smaller as background level is increased. In cones, higher background levels reduce the effectiveness of test flashes, so higher ranges of test intensities are required to elicit the full range of graded responses. When backgrounds are terminated, cones return rapidly, but rods return slowly to the dark potential level. The effects of backgrounds on both rods and cones can be observed at intensities that cause negligible bleaching as determined by retinal densitometry. During dark adaptation, changes are observed in the rods and cones that are similar to those produced by backgrounds. Receptor sensitivities, derived from these results, show that rods saturate, cones obey Weber's law, and sensitization during dark adaptation follows a two-phase time-course.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359063"}
{"pmid": "4359064", "title": "Control of retinal sensitivity. II. Lateral interactions at the outer plexi form layer.", "content": "Control of retinal sensitivity. II. Lateral interactions at the outer plexi form layer. Test stimuli, presented at the center of the bipolar cell receptive field, spanning less than 2 log units of intensity, elicit the full range of graded response. The intensity range of test stimuli that elicits the graded response depends upon the background conditions. A higher range of log test intensities is required to elicit the graded bipolar response in the presence of surround backgrounds. But surround backgrounds can also serve to unsaturate the bipolar response and thereby increase sensitivity under certain conditions. The results suggest that a second stage of sensitivity-control is mediated by the horizontal cell system at the outer plexiform layer, concatenated with the effects of adaptation in the photoreceptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359064"}
{"pmid": "4359065", "title": "Control of retinal sensitivity. 3. Lateral interactions at the inner plexiform layer.", "content": "Control of retinal sensitivity. 3. Lateral interactions at the inner plexiform layer. Both the \"on\" and the \"on-off\" ganglion cells in the mudpuppy retina generate graded responses over a narrow range of log test intensities. Sustained full field or surround backgrounds change the range of center log test intensities that elicits the graded response for both cell types. The on-off, but not the on ganglion cells are further affected by moving or flashing surround backgrounds. These cells are hyperpolarized, threshold is elevated, and the entire graded range of response is elicited by a higher range of log center test intensities. Depolarizing activity is elicited in amacrine cells by moving backgrounds that affect the on-off ganglion cells, but bipolar activity is unaffected. These results suggest that the amacrine cells at the inner plexiform layer mediate a third stage of sensitivity control in the retina, increasing threshold for response to change specifically in the on-off ganglion cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359065"}
{"pmid": "4359067", "title": "A systematist looks at cytochrome c.", "content": "A systematist looks at cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359067"}
{"pmid": "4359066", "title": "Sequence data: magnitude and implications of some ambiguities.", "content": "Sequence data: magnitude and implications of some ambiguities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359066"}
{"pmid": "4359068", "title": "Serotonergic and antiserotonergic influences on amphetamine-induced stereotyped behavior.", "content": "Serotonergic and antiserotonergic influences on amphetamine-induced stereotyped behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359068"}
{"pmid": "4359069", "title": "Acetylcholine and cortical excitation by pyramidal tract collaterals.", "content": "Acetylcholine and cortical excitation by pyramidal tract collaterals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359069"}
{"pmid": "4359070", "title": "Observations on bluetongue and epizootic hemorrhagic disease viruses in white-tailed deer: (1) distribution of virus in the blood (2) cross-challenge.", "content": "Observations on bluetongue and epizootic hemorrhagic disease viruses in white-tailed deer: (1) distribution of virus in the blood (2) cross-challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359070"}
{"pmid": "4359077", "title": "Mesodermal mixed tumors of the uterine corpus.", "content": "Mesodermal mixed tumors of the uterine corpus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359077"}
{"pmid": "4359079", "title": "Pituitary-adrenal hormones and extinction of rewarded behaviour in the rat.", "content": "Pituitary-adrenal hormones and extinction of rewarded behaviour in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359079"}
{"pmid": "4359078", "title": "The effect of large doses of medroxyprogesterone acetate (MPA) on urinary estrogen levels and serum levels of cortisol T4 LH and testosterone in patients with advanced cancer.", "content": "The effect of large doses of medroxyprogesterone acetate (MPA) on urinary estrogen levels and serum levels of cortisol T4 LH and testosterone in patients with advanced cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359078"}
{"pmid": "4359080", "title": "Neurologic complications of corticosteroid therapy.", "content": "Neurologic complications of corticosteroid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359080"}
{"pmid": "4359074", "title": "The adsorption of water in a chlorophyll extract.", "content": "The adsorption of water in a chlorophyll extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359074"}
{"pmid": "4359081", "title": "Increased serum conjugated bilirubin in hemolytic anemia.", "content": "Increased serum conjugated bilirubin in hemolytic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359081"}
{"pmid": "4359082", "title": "Female steroid hormones and target cell nuclei.", "content": "Female steroid hormones and target cell nuclei. The data discussed herein demonstrate the great variation in target-tissue response that can occur after administration of steroid hormones. The female sex steroids can exert regulatory effects on the synthesis, activity, and possibly even the degradation of tissue enzymes and structural proteins. Each response, nevertheless, appears to be dependent on the synthesis of nuclear RNA. In many instances, the steroid actually promotes a qualitative change in the base composition and sequence of the RNA synthesized by the target cell, implying a specific effect on gene transcription. Most important is our direct quantitative evidence that sex steroids cause a net increase in the intracellular amounts of specific mRNA molecules in target tissues. It thus appears that we are discovering a pattern of steroid hormone action which includes (Fig. 1): (i) uptake of the hormone by the target cell and binding to a specific cytoplasmic receptor protein; (ii) transport of the steroid-receptor complex to the nucleus; (iii) binding of this \"active\" complex to specific \"acceptor\" sites on the genome (chromatin DNA and acidic protein); (iv) activation of the transcriptional apparatus resulting in the appearance of new RNA species which includes specific mRNA's; (v) transport of the hormone-induced RNA to the cytoplasm resulting in synthesis of new proteins on cytoplasmic ribosomes; and (vi) the occurrence of the specific steroid-mediated \"functional response\" characteristic of that particular target tissue. To elucidate fully the mechanism of steroid hormone action we must study the biochemistry of the process by which information held by the steroid hormone-receptor complex is transferred to the nuclear transcription apparatus. If our assumptions are correct, we should ultimately be able to discover how this hormone-receptor complex exerts a specific regulatory effect on nuclear RNA metabolism. Such regulation might be achieved (i) by direct effects on chromatin template leading to increased gene transcription and thus RNA synthesis; (ii) by activation of the polymerase complex itself; (iii) by inhibition of RNA breakdown; or (iv) by intranuclear processing of large precursor molecules so that smaller biologically active sequences are produced, and (v) by transport of RNA from the nucleus to the cytoplasmic sites of cellular protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359082"}
{"pmid": "4359083", "title": "Failure to confirm cyclic AMP as second messenger for norepinephrine in rat cerebellum.", "content": "Failure to confirm cyclic AMP as second messenger for norepinephrine in rat cerebellum. Microiontophoretic applications of adenosine 3',5'-monophosphate (cyclic AMP) to spontaneously active, electrophysiologically identified Purkinje cells of the rat cerebellum failed to mimic the strong depressant action of norepinephrine on the same cells. These findings, in combination with a reevaluation of other studies, cast doubt on the hypothesis that cyclic AMP mediates the depressant actions of norepinephrine in the cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359083"}
{"pmid": "4359084", "title": "Viscosity of cellular protoplasm.", "content": "Viscosity of cellular protoplasm. The protoplasmic viscosity was studied by using a small spin label having high permeability and broad solubility properties and nickel chloride as an extracellular spin-subtracting agent to localize signal inside cells. The viscosity is variable and in some cells is many times that of water or phospholipids, suggesting that lateral diffusion in biological membranes is important to cell function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359084"}
{"pmid": "4359085", "title": "Diphenylhydantoin: effects on calcium metabolism in the chick.", "content": "Diphenylhydantoin: effects on calcium metabolism in the chick. Rickets, hypocalcemia, decreased duodenal calcium transport, and reduction of calcium binding protein have been produced in chicks treated with diphenylhydantoin. These effects are directly related to diphenylhydantoin dose and inversely related to the intake of vitamin D(3) (cholecalciferol).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359085"}
{"pmid": "4359076", "title": "Origin of the mitochondrial RNA of animal tissues. 2. Hybridization with nuclear DNA.", "content": "Origin of the mitochondrial RNA of animal tissues. 2. Hybridization with nuclear DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359076"}
{"pmid": "4359088", "title": "Observations on the role of viruses in pneumonia of calves.", "content": "Observations on the role of viruses in pneumonia of calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359088"}
{"pmid": "4359075", "title": "The molecular organization of the active sites of the microsomal cytochrome P-450.", "content": "The molecular organization of the active sites of the microsomal cytochrome P-450.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359075"}
{"pmid": "4359092", "title": "The IBR-IPV virus-serum neutralization test. Sensitivity and significance of the tissue culture tube test.", "content": "The IBR-IPV virus-serum neutralization test. Sensitivity and significance of the tissue culture tube test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359092"}
{"pmid": "4359093", "title": "Proteases of Clostridium botulinum. V. Studies on the serological relationship between proteases from Clostridium botulinum and other spore-forming bacteria.", "content": "Proteases of Clostridium botulinum. V. Studies on the serological relationship between proteases from Clostridium botulinum and other spore-forming bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359093"}
{"pmid": "4359095", "title": "Primary congenital eversion of the eyelids.", "content": "Primary congenital eversion of the eyelids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359095"}
{"pmid": "4359086", "title": "Conclusions from Bell's phenomenon variants.", "content": "Conclusions from Bell's phenomenon variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359086"}
{"pmid": "4359094", "title": "Peripheral plasma levels of corticosteroids in normal beagles and greyhounds measured by a rapid competitive protein binding technique.", "content": "Peripheral plasma levels of corticosteroids in normal beagles and greyhounds measured by a rapid competitive protein binding technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359094"}
{"pmid": "4359096", "title": "Stein-Leventhal syndrome in a 12-year-old girl.", "content": "Stein-Leventhal syndrome in a 12-year-old girl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359096"}
{"pmid": "4359097", "title": "Epstein-Barr virus antibodies in the cerebrospinal fluid. A case of infectious mononucleosis with encephalitis.", "content": "Epstein-Barr virus antibodies in the cerebrospinal fluid. A case of infectious mononucleosis with encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359097"}
{"pmid": "4359098", "title": "Galactography: a method of detection of unsuspected cancers.", "content": "Galactography: a method of detection of unsuspected cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359098"}
{"pmid": "4359099", "title": "Comparison of counterimmunoelectrophoresis with other serologic tests in the diagnosis of amebiasis.", "content": "Comparison of counterimmunoelectrophoresis with other serologic tests in the diagnosis of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359099"}
{"pmid": "4359101", "title": "Prolongation of a pancuronium-induced neuronmuscular blockade by polymyxin B.", "content": "Prolongation of a pancuronium-induced neuronmuscular blockade by polymyxin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359101"}
{"pmid": "4359102", "title": "Isolated facial numbness. Clinical significance and relation to trigeminal neuropathy.", "content": "Isolated facial numbness. Clinical significance and relation to trigeminal neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359102"}
{"pmid": "4359103", "title": "Endoscopic cholangiography for biliary system diagnosis.", "content": "Endoscopic cholangiography for biliary system diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359103"}
{"pmid": "4359104", "title": "Studies on bone matrix glycoproteins. Incorporation of (1-14C)glucosamine and plasma (14C)glycoprotein into rabbit cortical bone.", "content": "Studies on bone matrix glycoproteins. Incorporation of (1-14C)glucosamine and plasma (14C)glycoprotein into rabbit cortical bone. The radioactively labelled constituents present in bone matrix were compared 12 days after injection of either [(14)C]glucosamine or plasma [(14)C]glycoprotein. Both precursors are utilized in the synthesis of organic matrix by bone tissue. Cortical bone from animals injected with [(14)C]glucosamine contains radioactivity derived from glucosamine and plasma glycoproteins and all glycoprotein fractions are labelled. Plasma [(14)C]glycoprotein labels the less acidic glycoproteins to a greater extent than the more acidic components. An antibody has been raised against the less-acidic-glycoprotein fraction of bone. The latter contains a glycoprotein of alpha-mobility that appears to be concentrated specifically in bone tissue and which is present also in plasma. This alpha-glycoprotein accounts for a large proportion of the components labelled and retained in bone matrix after [(14)C]glucosamine injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359104"}
{"pmid": "4359106", "title": "Steroid-binding properties and stabilization of cytoplasmic glucocorticoid receptors from rat thymus cells.", "content": "Steroid-binding properties and stabilization of cytoplasmic glucocorticoid receptors from rat thymus cells. 1. A competitive binding assay was adapted for determination of the specific binding of glucocorticoids to cytoplasmic receptors from rat thymus cells. The steroid-receptor complexes prepared by incubation of a cytoplasmic fraction from rat thymus cells with [1,2-(3)H(2)]cortisol or with [1,2,4-(3)H(3)]triamcinolone acetonide had rates of dissociation at 37 degrees C similar to those from intact cells. 2. The cytoplasmic receptor was unstable at 3 degrees C, but the rate of inactivation was decreased in the presence of 2.5mm-EDTA. The steroid-receptor complex was stable. 3. Rate constants for association and for dissociation, and association constants, were determined for the interactions of cortisol, cortexolone, dexamethasone and triamcinolone acetonide with the cytoplasmic receptor at 3 degrees C. Differences in the association constants for different steroids could largely be accounted for by the differences in the rate constants for dissociation, but the rate constants for association did not vary greatly; the implications of these findings for the nature of the steroid-binding site are discussed. 4. A cytoplasmic fraction prepared from cells which had been incubated at 37 degrees C under anaerobic conditions bound much less [1,2-(3)H(2)]cortisol than did a fraction from aerobic cells, but the binding capacity was restored after exposure of the anaerobic cells to O(2). 5. The specific binding of [1,2-(3)H(2)]-cortisol to intact thymus cells incubated aerobically was not affected by the presence of 0.1mm-cycloheximide, nor did this concentration of cycloheximide inhibit the recovery of specific binding observed when anaerobic cells were transferred to an aerobic atmosphere. 6. The energy dependence of specific binding of cortisol to the receptor is discussed with reference to possible mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359106"}
{"pmid": "4359105", "title": "Transport of methionine and proline by rat liver slices and the effect of certain hormones.", "content": "Transport of methionine and proline by rat liver slices and the effect of certain hormones. 1. Transport characteristics of l-methionine and l-proline in rat liver slices in vitro were studied. 2. Intracellular concentration gradients for methionine were obtained. 3. Methionine uptake was inhibited by iodoacetate, dinitrophenol, Na(+)-free media and also by glycine, lysine, cysteine and dithiothreitol but not by alpha-aminoisobutyrate. 4. The rate of methionine metabolism in the slice was slow. 5. Puromycin inhibited methionine incorporation into protein, but not methionine uptake. 6. Methionine inhibited the transport of alpha-aminoisobutyrate but not of cystine. 7. Efflux and exchange diffusion of methionine was studied. 8. Amino acid transport in rat liver slices was not affected by thyroidectomy. 9. Addition of insulin, glucagon, adrenaline or cortisol did not affect the transport of methionine. 10. Addition of 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate increased methionine transport after a 120min incubation period in some experiments. 11. Studies of l-proline transport were invalidated because of the rapid evolution of CO(2) from the substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359105"}
{"pmid": "4359109", "title": "Rections of aliphatic methanesulfonates.", "content": "Rections of aliphatic methanesulfonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359109"}
{"pmid": "4359110", "title": "The phospholipid composition of human serum lipoprotein fractions separated by electrophoresis on agarose gel. Demonstration of a fraction with high lysolecithin content.", "content": "The phospholipid composition of human serum lipoprotein fractions separated by electrophoresis on agarose gel. Demonstration of a fraction with high lysolecithin content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359110"}
{"pmid": "4359111", "title": "Purification and some properties of the enzyme which conjugates sulfobromophthalein to glutathione in rat liver.", "content": "Purification and some properties of the enzyme which conjugates sulfobromophthalein to glutathione in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359111"}
{"pmid": "4359112", "title": "Urinary excretion of neutral steroid glucuronides with reference to the menstrual cycle.", "content": "Urinary excretion of neutral steroid glucuronides with reference to the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359112"}
{"pmid": "4359100", "title": "Synaptosomes, a possible system for the study of synaptic transmission.", "content": "Synaptosomes, a possible system for the study of synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359100"}
{"pmid": "4359114", "title": "Type 3 hyperlipoproteinaemia.", "content": "Type 3 hyperlipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359114"}
{"pmid": "4359113", "title": "The interaction between estradiol and human platelets.", "content": "The interaction between estradiol and human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359113"}
{"pmid": "4359115", "title": "Type V hyperlipoproteinaemia.", "content": "Type V hyperlipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359115"}
{"pmid": "4359116", "title": "Lipoproteins and hyperlipoproteinaemia.", "content": "Lipoproteins and hyperlipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359116"}
{"pmid": "4359117", "title": "Type IV hyperlipoproteinaemia.", "content": "Type IV hyperlipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359117"}
{"pmid": "4359118", "title": "Type I hyperlipoproteinaemia.", "content": "Type I hyperlipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359118"}
{"pmid": "4359119", "title": "Characteristics of cyclic 3',5'-nucleotide phosphodiesterase from the brain of the Madagascar cockroach (Gromphadorhina portentosa).", "content": "Characteristics of cyclic 3',5'-nucleotide phosphodiesterase from the brain of the Madagascar cockroach (Gromphadorhina portentosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359119"}
{"pmid": "4359121", "title": "Estradiol receptors in female rat hypothalamus in the developmental stages and during pubescence.", "content": "Estradiol receptors in female rat hypothalamus in the developmental stages and during pubescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359121"}
{"pmid": "4359120", "title": "A biochemical basis for differences in maximal diving time in aquatic mammals.", "content": "A biochemical basis for differences in maximal diving time in aquatic mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359120"}
{"pmid": "4359122", "title": "Heterogeneity of thyroid iodine turnover: last come, last served phenomenon.", "content": "Heterogeneity of thyroid iodine turnover: last come, last served phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359122"}
{"pmid": "4359123", "title": "Effects of prostaglandin E1, ethanol and TSH on the adenylate cyclase activity of beef thyroid plasma membranes and cyclic AMP content of dog thyroid slices.", "content": "Effects of prostaglandin E1, ethanol and TSH on the adenylate cyclase activity of beef thyroid plasma membranes and cyclic AMP content of dog thyroid slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359123"}
{"pmid": "4359124", "title": "Specificity of nucleotide-induced insulin secretion.", "content": "Specificity of nucleotide-induced insulin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359124"}
{"pmid": "4359125", "title": "Estradiol and 20alpha-dihydroprogesterone dehydrogenase activities in human endometrium during the menstrual cycle.", "content": "Estradiol and 20alpha-dihydroprogesterone dehydrogenase activities in human endometrium during the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359125"}
{"pmid": "4359126", "title": "The effects of dibutyryl cyclic AMP, aminophylline and propranolol on PTE-induced bone resorption in vitro.", "content": "The effects of dibutyryl cyclic AMP, aminophylline and propranolol on PTE-induced bone resorption in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359126"}
{"pmid": "4359127", "title": "Physical characteristics of the Ca++ compartments associated with in vitro ACTH release.", "content": "Physical characteristics of the Ca++ compartments associated with in vitro ACTH release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359127"}
{"pmid": "4359129", "title": "Variations in the levels of cytoplasmic glucocorticoid receptors in lungs of various species at different developmental stages.", "content": "Variations in the levels of cytoplasmic glucocorticoid receptors in lungs of various species at different developmental stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359129"}
{"pmid": "4359128", "title": "Effect of dibutyryl cyclic AMP on in vitro rat testis DNA, RNA and protein labeling.", "content": "Effect of dibutyryl cyclic AMP on in vitro rat testis DNA, RNA and protein labeling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359128"}
{"pmid": "4359131", "title": "Environmental calcium and the sensitivity of killifish (Fundulus heteroclitus) in bioassays for the hypocalcemic response to Stannius corpuscles from killifish and cod (Gadus morhua).", "content": "Environmental calcium and the sensitivity of killifish (Fundulus heteroclitus) in bioassays for the hypocalcemic response to Stannius corpuscles from killifish and cod (Gadus morhua).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359131"}
{"pmid": "4359130", "title": "Development of a radioligand tissue receptor assay for human follicle-stimulating hormone.", "content": "Development of a radioligand tissue receptor assay for human follicle-stimulating hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359130"}
{"pmid": "4359133", "title": "Changes in plasma ACTH and corticosteroid of the maternal and fetal sheep during hypoxia.", "content": "Changes in plasma ACTH and corticosteroid of the maternal and fetal sheep during hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359133"}
{"pmid": "4359132", "title": "The binding of tritiated aldosterone in the rat liver cytosol.", "content": "The binding of tritiated aldosterone in the rat liver cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359132"}
{"pmid": "4359134", "title": "Adenylate cyclase activity in bovine adrenal medulla.", "content": "Adenylate cyclase activity in bovine adrenal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359134"}
{"pmid": "4359135", "title": "An ultrastructural stereologic study of the effects of 3',5'-cyclic nucleotides on the zona glomerulosa of rat adrenal cortex.", "content": "An ultrastructural stereologic study of the effects of 3',5'-cyclic nucleotides on the zona glomerulosa of rat adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359135"}
{"pmid": "4359136", "title": "Structural studies on the heptose region of Salmonella lipopolysaccharides.", "content": "Structural studies on the heptose region of Salmonella lipopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359136"}
{"pmid": "4359137", "title": "Comparative study of photophosphorylation coupling factor-ligand complex by circular dichroism and chemical isolation.", "content": "Comparative study of photophosphorylation coupling factor-ligand complex by circular dichroism and chemical isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359137"}
{"pmid": "4359138", "title": "Ribonuclease activity in Escherichia coli polyribosomes.", "content": "Ribonuclease activity in Escherichia coli polyribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359138"}
{"pmid": "4359139", "title": "Intracellular titration of cyclic AMP bound to receptor proteins and correlation with cyclic-AMP levels in the surviving rat diaphragm.", "content": "Intracellular titration of cyclic AMP bound to receptor proteins and correlation with cyclic-AMP levels in the surviving rat diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359139"}
{"pmid": "4359140", "title": "A new immobilized NAD+ analogue, its application in affinity chromatography and as a functioning coenzyme.", "content": "A new immobilized NAD+ analogue, its application in affinity chromatography and as a functioning coenzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359140"}
{"pmid": "4359141", "title": "5-Aminolevulinic-acid synthetase of Rhodopseudomonas spheroides Y. Kinetic mechanism and inhibition by ATP.", "content": "5-Aminolevulinic-acid synthetase of Rhodopseudomonas spheroides Y. Kinetic mechanism and inhibition by ATP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359141"}
{"pmid": "4359142", "title": "Fluorescence study of liver-alcohol-dehydrogenase complexes with berberine and other ligands.", "content": "Fluorescence study of liver-alcohol-dehydrogenase complexes with berberine and other ligands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359142"}
{"pmid": "4359143", "title": "Rate-limiting factors in ethanol oxidation by isolated rat-liver parenchymal cells. Effect of ethanol concentration, fructose, pyruvate and pyrazole.", "content": "Rate-limiting factors in ethanol oxidation by isolated rat-liver parenchymal cells. Effect of ethanol concentration, fructose, pyruvate and pyrazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359143"}
{"pmid": "4359145", "title": "The effects of trypsin on the membrane-bound nicotinic acid oxidase in Pseudomonas ovalis Chester.", "content": "The effects of trypsin on the membrane-bound nicotinic acid oxidase in Pseudomonas ovalis Chester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359145"}
{"pmid": "4359146", "title": "Purification of plasma membranes from immature brain.", "content": "Purification of plasma membranes from immature brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359146"}
{"pmid": "4359147", "title": "A correlation between the buoyant density and the sedimentation coefficient of EMC viral polyribosomes.", "content": "A correlation between the buoyant density and the sedimentation coefficient of EMC viral polyribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359147"}
{"pmid": "4359148", "title": "Updating the sleeping pill.", "content": "Updating the sleeping pill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359148"}
{"pmid": "4359149", "title": "Problems of gravimetric dust sampling.", "content": "Problems of gravimetric dust sampling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359149"}
{"pmid": "4359151", "title": "Immunological factors in coalworkers' pneumoconiosis.", "content": "Immunological factors in coalworkers' pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359151"}
{"pmid": "4359152", "title": "Mixed dust fibrosis in mineworkers.", "content": "Mixed dust fibrosis in mineworkers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359152"}
{"pmid": "4359154", "title": "Respirable dust in bituminous coal mines in the U.S.", "content": "Respirable dust in bituminous coal mines in the U.S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359154"}
{"pmid": "4359153", "title": "Mineralogical characteristics of airborne dust in coal mines of Western Germany and their relations to pulmonary changes of coal hewers.", "content": "Mineralogical characteristics of airborne dust in coal mines of Western Germany and their relations to pulmonary changes of coal hewers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359153"}
{"pmid": "4359156", "title": "The determination of the size distribution of mine dusts using the Coulter Counter.", "content": "The determination of the size distribution of mine dusts using the Coulter Counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359156"}
{"pmid": "4359155", "title": "Characteristics of the airborne dust in British coal mines.", "content": "Characteristics of the airborne dust in British coal mines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359155"}
{"pmid": "4359158", "title": "The relation between pneumoconiosis and dust-exposure in British coal mines.", "content": "The relation between pneumoconiosis and dust-exposure in British coal mines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359158"}
{"pmid": "4359159", "title": "The attack rate of progressive massive fibrosis in British coalminers.", "content": "The attack rate of progressive massive fibrosis in British coalminers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359159"}
{"pmid": "4359160", "title": "A simple dust index applicable to various dust-contaminated occupations--a program of action for silicosis prophylaxis.", "content": "A simple dust index applicable to various dust-contaminated occupations--a program of action for silicosis prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359160"}
{"pmid": "4359161", "title": "Histochemistry of enzyme response to trauma in the neocortex and corpus callosum of developing rat brain.", "content": "Histochemistry of enzyme response to trauma in the neocortex and corpus callosum of developing rat brain. The enzyme response to injury of the brain was well localized and limited. Some enzymes, even in 12 day old brain, increased rapidly, mainly in neocortical glial cells. In the corpus callosum enzymes were not significantly hyperactive before the light myelination stage. Some hyperactivity declined after 21 days. Oxidative processes and phosphate metabolism were most disturbed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359161"}
{"pmid": "4359163", "title": "Sensory conduction in peroneal and posterior tibial nerves using averaging techniques.", "content": "Sensory conduction in peroneal and posterior tibial nerves using averaging techniques. A method of obtaining pure sensory nerve conduction velocities in the lower extremities is described. This involves the use of electronic summation (signal averaging). Potentials were obtained and velocities calculated from all normal subjects examined. In patients with peripheral neuropathies it was often possible to obtain nerve velocities with signal amplitudes as low as 0·1 μV and these were often slower than those obtained from the normal subjects. The advantages and disadvantages of this method are discussed. It is of significant clinical value in that pure sensory nerve conduction velocities can be measured in the legs when this may be the only valuable parameter in the absence of motor involvement. In addition, investigation of neuropathies at an earlier stage of development and recovery may be facilitated. It is hoped that in the future this technique of obtaining low amplitude responses with an analogue averager can be incorporated with the more routine aspects of nerve conduction testing when clinically indicated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359163"}
{"pmid": "4359162", "title": "Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy.", "content": "Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy. The narcoleptic syndrome is a life-long and sometimes familial disorder in which there is a disturbance of the rapid eye movement phase of sleep. Patients with periodic sleep in the daytime but no other symptoms seldom develop the narcoleptic syndrome and have a separate unrelated disorder. Twelve patients with the narcoleptic syndrome were treated separately with l(-) amphetamine and d(+) amphetamine. Both drugs abolished narcolepsy, d(+) amphetamine being slightly more potent than l(-) amphetamine. In equipotent doses, unwanted effects of nervousness and insomnia were equal in frequency. No tolerance to either preparation developed during a six month period. Cataplexy was not affected by amphetamine treatment, but was abolished in two patients when clomipramine was given together with either amphetamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359162"}
{"pmid": "4359164", "title": "A study of the H-reflex by single fibre EMG.", "content": "A study of the H-reflex by single fibre EMG. The latency of consecutive H-reflex responses of single human triceps surae motoneurones varies up to 2,500 μs. A large part of this variation was shown to occur at the synaptic transmission. A moderate increase in stimulus strength from the threshold value shortened the mean latency and reduced the latency variation, presumably as a result of spatial summation of excitatory inputs. Further increase to maximum strength lengthened the mean latency, increased the variation, and resulted in a dropping out of some responses which was not produced by collision by antidromic impulses. These effects are believed to be due to an active inhibition. Changes of the latency were also obtained by Jendrassik's manoeuvre and facilitatory and inhibitory conditioning stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359164"}
{"pmid": "4359165", "title": "The glomus bodies (\"paraganglia\") of the human larynx.", "content": "The glomus bodies (\"paraganglia\") of the human larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359165"}
{"pmid": "4359166", "title": "Studies on growth hormones.", "content": "Studies on growth hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359166"}
{"pmid": "4359167", "title": "Adsorption and reactions of chitinase and lysozyme on chitin.", "content": "Adsorption and reactions of chitinase and lysozyme on chitin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359167"}
{"pmid": "4359168", "title": "Selective binding properties of vitamin D transport protein in chick plasma in vitro.", "content": "Selective binding properties of vitamin D transport protein in chick plasma in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359168"}
{"pmid": "4359169", "title": "Awakening latency from sleep for meaningful and non-meaningful stimuli.", "content": "Awakening latency from sleep for meaningful and non-meaningful stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359169"}
{"pmid": "4359170", "title": "Some observations on the reliability of REM variables.", "content": "Some observations on the reliability of REM variables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359170"}
{"pmid": "4359171", "title": "Change in the activity of chemical mutagens during their interaction with seed metabolites.", "content": "Change in the activity of chemical mutagens during their interaction with seed metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359171"}
{"pmid": "4359172", "title": "Nature of the spots produced on the bodies of female Drosophila melanogaster under the influence of methylmethane sulfonate.", "content": "Nature of the spots produced on the bodies of female Drosophila melanogaster under the influence of methylmethane sulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359172"}
{"pmid": "4359174", "title": "The effect of certain amino acids on reproduction of encephalomyocarditis virus. II. Investigation of the inhibiting effect of L-histidine.", "content": "The effect of certain amino acids on reproduction of encephalomyocarditis virus. II. Investigation of the inhibiting effect of L-histidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359174"}
{"pmid": "4359178", "title": "Altered cellular responses to interferon induction by poly I-poly C: priming and hyporesponsiveness in cells treated with interferon preparations.", "content": "Altered cellular responses to interferon induction by poly I-poly C: priming and hyporesponsiveness in cells treated with interferon preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359178"}
{"pmid": "4359177", "title": "Sendai virus nucleocapsids in the nucleoli of infected cells.", "content": "Sendai virus nucleocapsids in the nucleoli of infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359177"}
{"pmid": "4359179", "title": "Foot-and-mouth disease: growth of virus after conjunctival inoculation of cattle. Brief report.", "content": "Foot-and-mouth disease: growth of virus after conjunctival inoculation of cattle. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359179"}
{"pmid": "4359185", "title": "Reflections on possible mechanisms of action of anti-inflammatory drugs.", "content": "Reflections on possible mechanisms of action of anti-inflammatory drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359185"}
{"pmid": "4359186", "title": "Biochemical properties of a defective hamster C-type oncornavirus.", "content": "Biochemical properties of a defective hamster C-type oncornavirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359186"}
{"pmid": "4359187", "title": "A proposed regulator for poliovirus: the equestron.", "content": "A proposed regulator for poliovirus: the equestron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359187"}
{"pmid": "4359180", "title": "The effect of D-thyroxine on the metabolism of cholesterol in familial hyperbetalipoproteinaemia.", "content": "The effect of D-thyroxine on the metabolism of cholesterol in familial hyperbetalipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359180"}
{"pmid": "4359188", "title": "Total recovery of infectious virus from noninfectious type 1 poliovirus-antibody complex by heating in salts.", "content": "Total recovery of infectious virus from noninfectious type 1 poliovirus-antibody complex by heating in salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359188"}
{"pmid": "4359189", "title": "Radioimmunoassay of avian RNA tumor virus group-specific antigen.", "content": "Radioimmunoassay of avian RNA tumor virus group-specific antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359189"}
{"pmid": "4359181", "title": "The very low density lipoproteins of cholesterol-fed rabbits. A study of their structure and in vivo changes in plasma.", "content": "The very low density lipoproteins of cholesterol-fed rabbits. A study of their structure and in vivo changes in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359181"}
{"pmid": "4359190", "title": "Rapid diagnosis of enterovirus meningitis by immunofluorescent staining of CSF leukocytes.", "content": "Rapid diagnosis of enterovirus meningitis by immunofluorescent staining of CSF leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359190"}
{"pmid": "4359183", "title": "Clinical and metabolic effects of pentaerythritol tetranicotinate(Perycit)and a comparison with plain nicotinic acid.", "content": "Clinical and metabolic effects of pentaerythritol tetranicotinate(Perycit)and a comparison with plain nicotinic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359183"}
{"pmid": "4359191", "title": "Observations on the rescue of simian virus 40 induced by cell fusion from heterokaryon cultures using electron autoradiography.", "content": "Observations on the rescue of simian virus 40 induced by cell fusion from heterokaryon cultures using electron autoradiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359191"}
{"pmid": "4359192", "title": "Multiplicity reactivation in UV-irradiated herpes simplex type 1 virus.", "content": "Multiplicity reactivation in UV-irradiated herpes simplex type 1 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359192"}
{"pmid": "4359182", "title": "The effect of combined treatment with phenformin and stanazolol on blood lipids and fibrinolytic activity in patients with hypertriglyceridaemia.", "content": "The effect of combined treatment with phenformin and stanazolol on blood lipids and fibrinolytic activity in patients with hypertriglyceridaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359182"}
{"pmid": "4359193", "title": "Deoxythymidine kinase from rabbit kidney cells infected with herpes simplex virus types 1 and 2.", "content": "Deoxythymidine kinase from rabbit kidney cells infected with herpes simplex virus types 1 and 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359193"}
{"pmid": "4359194", "title": "Thymidine kinase activity of herpes simplex virus temperature-sensitive mutants.", "content": "Thymidine kinase activity of herpes simplex virus temperature-sensitive mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359194"}
{"pmid": "4359197", "title": "Hodgkin's disease: involvement of viral agents in the etiology.", "content": "Hodgkin's disease: involvement of viral agents in the etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359197"}
{"pmid": "4359196", "title": "Effect of various enzymes and chelating agents on SV40 tumor-specific transplantation antigens.", "content": "Effect of various enzymes and chelating agents on SV40 tumor-specific transplantation antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359196"}
{"pmid": "4359195", "title": "Potentiation of effect of prolactin by adrenocorticotropic and growth hormones upon weight and nucleic acids contents of female rat mammary gland.", "content": "Potentiation of effect of prolactin by adrenocorticotropic and growth hormones upon weight and nucleic acids contents of female rat mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359195"}
{"pmid": "4359199", "title": "Low resolution structure of adenylate kinase.", "content": "Low resolution structure of adenylate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359199"}
{"pmid": "4359198", "title": "Nuclear magnetic resonance study of the rate of electron transfer between cytochrome c and iron hexacyanides.", "content": "Nuclear magnetic resonance study of the rate of electron transfer between cytochrome c and iron hexacyanides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359198"}
{"pmid": "4359200", "title": "Properties of the genome in experimental hepatomas: variations in the composition of chromatin.", "content": "Properties of the genome in experimental hepatomas: variations in the composition of chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359200"}
{"pmid": "4359201", "title": "Lipids of cultured hepatoma cells. I. Effect of serum lipid levels on cell and media lipids.", "content": "Lipids of cultured hepatoma cells. I. Effect of serum lipid levels on cell and media lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359201"}
{"pmid": "4359202", "title": "Lipids of cultured hepatoma cells. II. Effect of media lipids on cellular phospholipids.", "content": "Lipids of cultured hepatoma cells. II. Effect of media lipids on cellular phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359202"}
{"pmid": "4359203", "title": "Alternate pathways of cerebroside catabolism.", "content": "Alternate pathways of cerebroside catabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359203"}
{"pmid": "4359205", "title": "Removal of lipid from intact erythrocytes and ghosts by aqueous solutions and its relevance to membrane structure.", "content": "Removal of lipid from intact erythrocytes and ghosts by aqueous solutions and its relevance to membrane structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359205"}
{"pmid": "4359204", "title": "Immunochemical quantification of human plasma Lp(a) lipoprotein.", "content": "Immunochemical quantification of human plasma Lp(a) lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359204"}
{"pmid": "4359206", "title": "Ultrastructural findings in acrodermatitis enteropathica.", "content": "Ultrastructural findings in acrodermatitis enteropathica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359206"}
{"pmid": "4359208", "title": "The ultrastructure of a transplantable rat hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene.", "content": "The ultrastructure of a transplantable rat hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359208"}
{"pmid": "4359207", "title": "Persistence of adenylate kinase and other enzymes in glycerol extracted muscle.", "content": "Persistence of adenylate kinase and other enzymes in glycerol extracted muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359207"}
{"pmid": "4359210", "title": "Pyruvate and citrate concentrations in rabbit aqueous humour determined by an enzymatic procedure.", "content": "Pyruvate and citrate concentrations in rabbit aqueous humour determined by an enzymatic procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359210"}
{"pmid": "4359209", "title": "Enzymes of carbohydrate metabolism in rat hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene.", "content": "Enzymes of carbohydrate metabolism in rat hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359209"}
{"pmid": "4359211", "title": "NMR investigations of caffeine-sodium benzoate interactions.", "content": "NMR investigations of caffeine-sodium benzoate interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359211"}
{"pmid": "4359212", "title": "Ultrastructure of sarcoma 180 cells in mice treated with testosterone propionate.", "content": "Ultrastructure of sarcoma 180 cells in mice treated with testosterone propionate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359212"}
{"pmid": "4359214", "title": "mRNA synthesis in erythropoiesis: specific effect of erythropoietin on the synthesis of DNA-like RNA.", "content": "mRNA synthesis in erythropoiesis: specific effect of erythropoietin on the synthesis of DNA-like RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359214"}
{"pmid": "4359215", "title": "Messenger RNA processing in vertebrate cells.", "content": "Messenger RNA processing in vertebrate cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359215"}
{"pmid": "4359216", "title": "Reconstitution of 50S ribosomal subunits and the role of 5S RNA.", "content": "Reconstitution of 50S ribosomal subunits and the role of 5S RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359216"}
{"pmid": "4359217", "title": "Studies on HeLa cell nucleoli.", "content": "Studies on HeLa cell nucleoli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359217"}
{"pmid": "4359218", "title": "Antibiotic action in protein synthesis.", "content": "Antibiotic action in protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359218"}
{"pmid": "4359219", "title": "Modifications of polysome-associated RNA after poliovirus infection.", "content": "Modifications of polysome-associated RNA after poliovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359219"}
{"pmid": "4359221", "title": "Electrical activity in dissociated cell cultures from fetal mouse cerebellum.", "content": "Electrical activity in dissociated cell cultures from fetal mouse cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359221"}
{"pmid": "4359220", "title": "Synthesis of mitochondrial proteins.", "content": "Synthesis of mitochondrial proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359220"}
{"pmid": "4359222", "title": "The role of norepinephrine in the function of the area postrema. II. In vitro incubation and stimulated release of tritiated norepinephrine.", "content": "The role of norepinephrine in the function of the area postrema. II. In vitro incubation and stimulated release of tritiated norepinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359222"}
{"pmid": "4359223", "title": "In vivo studies on the effect of 6-hydroxydopamine on amino acid metabolism in brain.", "content": "In vivo studies on the effect of 6-hydroxydopamine on amino acid metabolism in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359223"}
{"pmid": "4359224", "title": "The effect of mesencephalic reticular stimulation on intracellular potentials of cat lateral geniculate neurons.", "content": "The effect of mesencephalic reticular stimulation on intracellular potentials of cat lateral geniculate neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359224"}
{"pmid": "4359225", "title": "Brain stem stimulation and the hypothesis of presynaptic inhibition in cat lateral geniculate nucleus.", "content": "Brain stem stimulation and the hypothesis of presynaptic inhibition in cat lateral geniculate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359225"}
{"pmid": "4359226", "title": "The use of counter-current distribution to examine the effect of damaging agents on DNA.", "content": "The use of counter-current distribution to examine the effect of damaging agents on DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359226"}
{"pmid": "4359227", "title": "The biosynthesis and secretion of insulin.", "content": "The biosynthesis and secretion of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359227"}
{"pmid": "4359228", "title": "Insulin and insulin-like substances in the circulation.", "content": "Insulin and insulin-like substances in the circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359228"}
{"pmid": "4359229", "title": "Respiratory function on asthmatic patients using beclomethasone dipropionate administered by pressurised aerosol.", "content": "Respiratory function on asthmatic patients using beclomethasone dipropionate administered by pressurised aerosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359229"}
{"pmid": "4359230", "title": "Enzymology of kidney tissue.", "content": "Enzymology of kidney tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359230"}
{"pmid": "4359231", "title": "Enzymes and isoenzymes in urine.", "content": "Enzymes and isoenzymes in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359231"}
{"pmid": "4359232", "title": "Alkaline phosphatase activity in canine renal homografts.", "content": "Alkaline phosphatase activity in canine renal homografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359232"}
{"pmid": "4359233", "title": "Neurologic examination.", "content": "Neurologic examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359233"}
{"pmid": "4359234", "title": "Absorption and secretion of salt and water by the small intestine.", "content": "Absorption and secretion of salt and water by the small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359234"}
{"pmid": "4359235", "title": "The manganous-adenosine triphosphate system. A reinvestigation of its proton magnetic resonance spectra.", "content": "The manganous-adenosine triphosphate system. A reinvestigation of its proton magnetic resonance spectra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359235"}
{"pmid": "4359236", "title": "A 99mTc-pyrophosphate kit: a convenient, economical, and high-quality skeletal-imaging agent.", "content": "A 99mTc-pyrophosphate kit: a convenient, economical, and high-quality skeletal-imaging agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359236"}
{"pmid": "4359237", "title": "Ultracentrifugal studies with absorption optics and a split-beam photoelectric scanner.", "content": "Ultracentrifugal studies with absorption optics and a split-beam photoelectric scanner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359237"}
{"pmid": "4359238", "title": "Chromatography of proteins on hydroxyapatite.", "content": "Chromatography of proteins on hydroxyapatite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359238"}
{"pmid": "4359239", "title": "Magneto optical rotation spectroscopy.", "content": "Magneto optical rotation spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359239"}
{"pmid": "4359240", "title": "Study on tumour specific cell surface antigen in avian sarcoma virus-induced mammaliam cells with the aid of peroxidase-labelled antibody.", "content": "Study on tumour specific cell surface antigen in avian sarcoma virus-induced mammaliam cells with the aid of peroxidase-labelled antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359240"}
{"pmid": "4359241", "title": "Electrophoretic properties of the product of protein synthesis in mitochondria of rat liver and Zajdela hepatoma.", "content": "Electrophoretic properties of the product of protein synthesis in mitochondria of rat liver and Zajdela hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359241"}
{"pmid": "4359242", "title": "Fusion of XC rat sarcoma cells induced by murine leukaemia virus-infected mouse mammary tumour cells. Absence of interference by simultaneously synthesized mammary tumour virus.", "content": "Fusion of XC rat sarcoma cells induced by murine leukaemia virus-infected mouse mammary tumour cells. Absence of interference by simultaneously synthesized mammary tumour virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359242"}
{"pmid": "4359243", "title": "Herpesviruses from fish to man--a search for pathobiologic unity.", "content": "Herpesviruses from fish to man--a search for pathobiologic unity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359243"}
{"pmid": "4359244", "title": "Demyelinating diseases and certain virus infections.", "content": "Demyelinating diseases and certain virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359244"}
{"pmid": "4359245", "title": "The relation between structure and function in mitochondria. Its relevance in pathology.", "content": "The relation between structure and function in mitochondria. Its relevance in pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359245"}
{"pmid": "4359246", "title": "Growth kinetics of solid tumors.", "content": "Growth kinetics of solid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359246"}
{"pmid": "4359248", "title": "Activity of hydrolytic enzymes in a case of subacute multiple sclerosis.", "content": "Activity of hydrolytic enzymes in a case of subacute multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359248"}
{"pmid": "4359250", "title": "The immunizing effect of commercial pigeon pox vaccines on pigeons.", "content": "The immunizing effect of commercial pigeon pox vaccines on pigeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359250"}
{"pmid": "4359249", "title": "Herpes simplex encephalitis. A report of three further cases.", "content": "Herpes simplex encephalitis. A report of three further cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359249"}
{"pmid": "4359251", "title": "Inefficacy of dietary deficiencies of vitamins A, D3 and riboflavin on the reproductive performance of mature cockerels.", "content": "Inefficacy of dietary deficiencies of vitamins A, D3 and riboflavin on the reproductive performance of mature cockerels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359251"}
{"pmid": "4359253", "title": "Renal transplantation in children.", "content": "Renal transplantation in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359253"}
{"pmid": "4359252", "title": "Plasma renin activity (PRA) in 89 patients on regular haemodialysis.", "content": "Plasma renin activity (PRA) in 89 patients on regular haemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359252"}
{"pmid": "4359255", "title": "The presence of glycogen synthase in preparations of platelet plasma membranes.", "content": "The presence of glycogen synthase in preparations of platelet plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359255"}
{"pmid": "4359254", "title": "Regulation of aldosterone in anephric man maintained with regular haemodialysis.", "content": "Regulation of aldosterone in anephric man maintained with regular haemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359254"}
{"pmid": "4359265", "title": "Adrenergic and cholinergic innervation of the turtle heart ventricle.", "content": "Adrenergic and cholinergic innervation of the turtle heart ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359265"}
{"pmid": "4359264", "title": "Ultrastructure of the rat posterior pituitary gland and evidence of hormone release by exocytosis as revealed by freeze-fracturing.", "content": "Ultrastructure of the rat posterior pituitary gland and evidence of hormone release by exocytosis as revealed by freeze-fracturing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359264"}
{"pmid": "4359267", "title": "The capillaries of the middle ear mucosa in the guinea pig. Ultrastructure and permeability.", "content": "The capillaries of the middle ear mucosa in the guinea pig. Ultrastructure and permeability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359267"}
{"pmid": "4359263", "title": "Histochemical changes in the digestive gland of Lymnaea truncatula infected with Fasciola hepatica.", "content": "Histochemical changes in the digestive gland of Lymnaea truncatula infected with Fasciola hepatica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359263"}
{"pmid": "4359266", "title": "The terminal neuromuscular junctions of lower chordates.", "content": "The terminal neuromuscular junctions of lower chordates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359266"}
{"pmid": "4359271", "title": "Environmental modifications for controlling acute respiratory disease.", "content": "Environmental modifications for controlling acute respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359271"}
{"pmid": "4359272", "title": "Experimental reovirus infection in monkeys. II. Serologic studies.", "content": "Experimental reovirus infection in monkeys. II. Serologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359272"}
{"pmid": "4359273", "title": "The distribution of incubation periods of neoplastic diseases.", "content": "The distribution of incubation periods of neoplastic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359273"}
{"pmid": "4359275", "title": "The genetic structure of a tribal population, the Yanomama Indians. IX. Gene frequencies for 18 serum protein and erythrocyte enzyme systems in the Yanomama and five neighboring tribes: nine new variants.", "content": "The genetic structure of a tribal population, the Yanomama Indians. IX. Gene frequencies for 18 serum protein and erythrocyte enzyme systems in the Yanomama and five neighboring tribes: nine new variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359275"}
{"pmid": "4359274", "title": "Probable autosomal recessive inheritance in a family with Albright's hereditary osteodystrophy and an evaluation of the genetics of the disorder.", "content": "Probable autosomal recessive inheritance in a family with Albright's hereditary osteodystrophy and an evaluation of the genetics of the disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359274"}
{"pmid": "4359277", "title": "Epstein-Barr virus (EBV)-induced transformation of human lymphoid cells and immunosurveillance against lymphoma development.", "content": "Epstein-Barr virus (EBV)-induced transformation of human lymphoid cells and immunosurveillance against lymphoma development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359277"}
{"pmid": "4359276", "title": "Systemic eosinophilic infiltrative disease (SEIDI).", "content": "Systemic eosinophilic infiltrative disease (SEIDI).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359276"}
{"pmid": "4359278", "title": "Comparison of the direct and indirect immunoferritin tagging of Sendai virus antigen.", "content": "Comparison of the direct and indirect immunoferritin tagging of Sendai virus antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359278"}
{"pmid": "4359279", "title": "The comparative approach to physiological psychology.", "content": "The comparative approach to physiological psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359279"}
{"pmid": "4359280", "title": "Optic nerve pit and associated coloboma with serous detachment.", "content": "Optic nerve pit and associated coloboma with serous detachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359280"}
{"pmid": "4359281", "title": "Plasma renin levels in the normal and anephric fetus at birth.", "content": "Plasma renin levels in the normal and anephric fetus at birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359281"}
{"pmid": "4359283", "title": "\"Primary\" pulmonary histiocytosis X.", "content": "\"Primary\" pulmonary histiocytosis X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359283"}
{"pmid": "4359282", "title": "Corticotrophin and cortisol concentrations in the plasma of the chronically catheterised sheep fetus.", "content": "Corticotrophin and cortisol concentrations in the plasma of the chronically catheterised sheep fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359282"}
{"pmid": "4359284", "title": "Prolonged respirator support for the treatment of intractable myasthenia gravis.", "content": "Prolonged respirator support for the treatment of intractable myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359284"}
{"pmid": "4359285", "title": "2,3-Diphosphoglycerate fluctuations in erythrocytes reflecting pronounced blood glucose variation. In-vivo and in-vitro studies in normal, diabetic and hypoglycaemic subjects.", "content": "2,3-Diphosphoglycerate fluctuations in erythrocytes reflecting pronounced blood glucose variation. In-vivo and in-vitro studies in normal, diabetic and hypoglycaemic subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359285"}
{"pmid": "4359287", "title": "Immunoadjuvant activity of bacterial fractions on antibody-forming cells during the primary immune response period.", "content": "Immunoadjuvant activity of bacterial fractions on antibody-forming cells during the primary immune response period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359287"}
{"pmid": "4359288", "title": "Ascending connections of a midbrain auditory area in a crocodile, Caiman crocodilus.", "content": "Ascending connections of a midbrain auditory area in a crocodile, Caiman crocodilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359288"}
{"pmid": "4359289", "title": "Ascending connections of a thalamic auditory area in a crocodile, caiman crocodilus.", "content": "Ascending connections of a thalamic auditory area in a crocodile, caiman crocodilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359289"}
{"pmid": "4359290", "title": "Uses and abuses of corticosteroids.", "content": "Uses and abuses of corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359290"}
{"pmid": "4359291", "title": "Partial hepatectomy in metastatic Wilms' tumor.", "content": "Partial hepatectomy in metastatic Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359291"}
{"pmid": "4359292", "title": "Cancer in children with primary immunodeficiency diseases.", "content": "Cancer in children with primary immunodeficiency diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359292"}
{"pmid": "4359286", "title": "Ulceration of the colon associated with rheumatoid arthritis and steroid treatment: report of a case.", "content": "Ulceration of the colon associated with rheumatoid arthritis and steroid treatment: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359286"}
{"pmid": "4359293", "title": "Molecular weight determination of Sendai and Newcastle disease virus RNA.", "content": "Molecular weight determination of Sendai and Newcastle disease virus RNA. The molecular weights of Sendai and Newcastle disease virus RNA were estimated by sedimentation in sucrose gradients and by length measurements in the electron microscope under both denaturing and nondenaturing conditions. Sedimentation analyses under denaturing conditions yielded molecular weight estimates of 2.3 x 10(6) to 2.6 x 10(6), whereas length measurements yielded estimates of 5.2 x 10(6) to 5.6 x 10(6) for both denatured and nondenatured viral RNA. It would appear that the conditions of denaturation used (99% dimethyl sulfoxide at 26 C, and reaction with 1.1 M formaldehyde for 10 min at 60 C) do not equally denature parainfluenza virus RNA and other RNAs, such as cellular rRNA, 45S rRNA precursor, and R17 RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359293"}
{"pmid": "4359294", "title": "Interactions of polyoma and mouse DNAs. I. Lytic infection of bromodeoxyuridine-prelabeled mouse embryo cells.", "content": "Interactions of polyoma and mouse DNAs. I. Lytic infection of bromodeoxyuridine-prelabeled mouse embryo cells. On CsCl isopycnic centrifugation of the DNA extracted from secondary mouse embryo (ME) cultures grown in the presence of 5-bromodeoxyuridine (BUdR) and 5-fluorodeoxyuridine (FUdR) for 40 h, 10 to 25% of the DNA was found to be unsubstituted, 70 to 80% was bromouracil-hybrid DNA, and 5 to 10% was heavy DNA. These results together with cell number determinations, autoradiography, and Feulgen microspectrophotometry revealed three types of cells in these cultures: (i) 60 to 80% of the cells replicated their DNA once, divided, and then stopped mitotic activity, (ii) 5 to 10% were going through a second round of DNA replication; whereas (iii) 10 to 30% did not replicate DNA during the BUdR-FUdR exposure. After the transfer of these cultures to normal medium (without BUdR-FUdR), up to 20% of the cells resumed DNA synthesis asynchronously within 60 h, but no increase in cell number was observed. BUdR-FUdR-treated cultures, which were infected with polyoma virus in the absence of the thymidine analogues, supported a lytic infection to the same extent as did untreated ME cultures. This was concluded from the similar number of cells, which were induced to synthesize DNA, from the similar replication rate of the viral DNA, from the similar number of cells containing polyoma capsid proteins, and from the similar yields of progeny virus determined by hemagglutination and plaque formation. Thus, BUdR-prelabeled ME cultures are suitable for the investigation of interactions of the polyoma and mouse genomes during the lytic infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359294"}
{"pmid": "4359295", "title": "Interactions of polyoma and mouse DNA's. II. Polyoma-induced mouse DNA replication and pseudovirion formation.", "content": "Interactions of polyoma and mouse DNA's. II. Polyoma-induced mouse DNA replication and pseudovirion formation. Secondary mouse embryo (ME) cultures which had been grown prior to infection in the presence of 5-bromodeoxyuridine (BUdR) and 5-fluorodeoxy-uridine were found to be permissive for polyoma virus (16). The DNA extracted from the progeny virus yielded two bands on CsCl isopycnic centrifugation. The light band (LL) contained supercoiled circular (polyoma DNA I), open circular (polyoma DNA II), and linear (polyoma DNA III) molecules, as was seen by electron microscopy. The hybrid band (HL) contained exclusively linear molecules. This DNA was pure, density - labeled, pseudovirion DNA, i.e., fragmented HL mouse DNA. The quantitative comparison of HL and LL polyoma DNA III from six different virus preparations always revealed an excess of HL DNA, the ratio of HL/LL being between 1.2 and 2.2. These results led to the conclusion that in BUdR-prelabeled, polyoma-infected ME cells pseudovirion DNA is excised both from unreplicated and newly replicated regions of mouse DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359295"}
{"pmid": "4359297", "title": "Control of simian virus 40 gene expression in adenovirus-simian virus 40 hybrid viruses. Synthesis of hybrid adenovirus 2-simian virus 40 RNA molecules in cells infected with a nondefective adenovirus 2-simian virus 40 hybrid virus.", "content": "Control of simian virus 40 gene expression in adenovirus-simian virus 40 hybrid viruses. Synthesis of hybrid adenovirus 2-simian virus 40 RNA molecules in cells infected with a nondefective adenovirus 2-simian virus 40 hybrid virus. The effect of interferon on simian virus 40 (SV40) and adenovirus 2 (Ad2) T antigen synthesis has been examined in cells infected with SV40, with Ad2, and with a nondefective Ad2-SV40 hybrid virus, Ad2(+)ND(4). The induction of SV40 T antigen by SV40 was highly sensitive to interferon, whereas the induction of Ad2 T-antigen by Ad2 was resistant. This difference in interferon sensitivity was also noted in cells simultaneously infected with both viruses. However, the induction of SV40 T antigen by Ad2(+)ND(4), which contains covalently linked SV40 and Ad2 DNAs, was as resistant to interferon as the induction of Ad2 T antigen. This change in the interferon sensitivity of SV40 T antigen synthesis suggests that the expression of at least this portion of the SV40 genetic information in Ad2(+)ND(4) is under Ad2 genetic control. When RNA extracted from Ad2(+)ND(4)-infected cells was examined by means of sequential hybridization with Ad2 DNA, elution, and rehybridization with SV40 DNA, 27% of the SV40-specific RNA was found to be linked to Ad2 RNA. No such linkage was detected in control mixtures of Ad2 and SV40 RNAs. The presence of Ad2 and SV40 nucleotide sequences in the same RNA molecule implies that, in Ad2(+)ND(4) infection, transcription is initiated in the DNA of one virus (Ad2 or SV40) and continues without interruption across the point of junction into the DNA of the other virus. Furthermore, the interferon resistance of Ad2(+)ND(4)-induced SV40 T antigen synthesis suggests that transcription of the genetic information for SV40 T antigen is initiated in a region of Ad2 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359297"}
{"pmid": "4359296", "title": "Isolation and characterization of Sendai virus temperature-sensitive mutants.", "content": "Isolation and characterization of Sendai virus temperature-sensitive mutants. Ten temperature-sensitive mutants of Sendai virus, a paramyxovirus, were isolated and partially characterized. The mutants replicated in chicken embryo lung cells at 30 C, but not at 38 C; wild-type virus grew equally well at both temperatures. Complementation tests divided the mutants into seven groups. Six groups synthesized neither infectious virus nor RNA when incubated at 38 C from the beginning of infection. Temperature shift-up experiments demonstrated that three of these complementation groups were blocked in early steps required for RNA synthesis, but these gene functions were not needed throughout the replicative cycle. In contrast, the other three RNA-negative complementation groups were defective throughout the replicative cycle in functions required for virus-specific RNA synthesis. Only one mutant, which complemented all of the above, synthesized RNA but not infectious virus when placed at 38 C; the hemagglutinin of this mutant functioned only at the permissive temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359296"}
{"pmid": "4359299", "title": "Virus replication in enucleate cells: vesicular stomatitis virus and influenza virus.", "content": "Virus replication in enucleate cells: vesicular stomatitis virus and influenza virus. The requirement of the presence of a nucleus for the replication of vesicular stomatitis virus and influenza virus has been examined by following the growth and development of these viruses in enucleate BS-C-1 cells. Vesicular stomatitis virus replicates normally in enucleate cells with the rate of production of infectious virus, the amount of virus-specific protein synthesis, and the type of proteins produced being essentially the same in nucleate and enucleate cells. Influenza virus does not replicate in enucleate cells, no virus gene products can be detected, and there is no inhibition of cellular protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359299"}
{"pmid": "4359301", "title": "Phosphorylation of vesicular stomatitis virus in vivo and in vitro.", "content": "Phosphorylation of vesicular stomatitis virus in vivo and in vitro. The structural protein, NS, of purified vesicular stomatitis virus (VSV) is a phosphoprotein. In infected cells phosphorylated NS is found both free in the cytoplasm and as part of the viral ribonucleoprotein (RNP) complex containing both the 42S RNA and the structural proteins L, N, and NS, indicating that phosphorylation occurs as an early event in viral maturation. VSV contains an endogenous protein kinase activity, probably of host region, which catalyzes the in vitro phosphorylation of the viral proteins NS, M, and L, but not of N or G. The phosphorylated sites on NS appear to be different in the in vivo and in vitro reactions, and are differentially sensitive to alkaline phosphatase. After removal of the membrane components of purified VSV with a dextran-polyethylene glycol two-phase separation, the kinase activity remains tightly associated with the viral RNP. However, viral RNP isolated from infected cells shows only a small amount of kinase activity. The protein kinase enzyme appears to be a cellular contaminant of purified VSV because an activity from the uninfected cell extract can phosphorylate in vitro the dissociated viral proteins NS and M. The virion-associated activity may be derived either from the cytoplasm or the plasma membrane of the host cell since both of these cellular components contain protein kinase activity similar to that found in purified VSV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359301"}
{"pmid": "4359298", "title": "Primate and murine type-C viral nucleic acid association kinetics: analysis of model systems and natural tissues.", "content": "Primate and murine type-C viral nucleic acid association kinetics: analysis of model systems and natural tissues. Hybridization studies employing single-stranded (3)H-DNA transcripts of type-C viruses isolated from a woolly monkey or gibbon ape failed to detect nucleic acid sequences homologous to these viruses in the DNA from a variety of uninfected primate species. The possible significance of these results for the epidemiology of type-C viruses in primates is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359298"}
{"pmid": "4359300", "title": "Structure of the mouse mammary tumor virus: polypeptides and glycoproteins.", "content": "Structure of the mouse mammary tumor virus: polypeptides and glycoproteins. The polypeptide and glycoprotein compositions of the mouse mammary tumor virus virion from primary monolayer cultures of BALB/cfC3H mouse mammary tumor cells were studied by polyacrylamide gel electrophoresis by using internal and external labeling and Coomassie blue and periodic acid Schiff (PAS) staining. Twelve polypeptides were reproducibly resolved by the combined methods. Five major polypeptides were demonstrable with estimated molecular weights of 52,000, 36,000, 28,000, 14,000, and 10,000. Seven minor polypeptides were also consistently detected and had estimated molecular weights of 70,000, 60,000, 46,000, 38,000, 30,000, 22,000, and 17,000. Carbohydrate was associated with five of these polypeptides as measured by PAS stain or [(3)H] glucosamine labeling, or both. These glycoproteins had estimated molecular weights of 70,000, 60,000, 52,000, 36,000 and 10,000. The majority of the PAS stain and glucosamine was found in the 52,000 and 36,000 dalton peaks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359300"}
{"pmid": "4359303", "title": "Preliminary observations pertaining to polyadenylation of rhinovirus RNA.", "content": "Preliminary observations pertaining to polyadenylation of rhinovirus RNA. Human rhinovirus type 14 contained polyadenylated RNA. Virus growth in HeLa cells was inhibited by cordycepin or polyuridilic acid and stimulated by polyadenylic acid. Polyadenylic acid also reversed cordycepin inhibition of virus-induced cytopathology of infected HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359303"}
{"pmid": "4359305", "title": "Proposal for numbering mutants of avian leukosis and sarcoma viruses.", "content": "Proposal for numbering mutants of avian leukosis and sarcoma viruses. A system for the numbering of mutants of avian sarcoma and leukosis viruses is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359305"}
{"pmid": "4359304", "title": "Protein kinase associated with Sendai virions.", "content": "Protein kinase associated with Sendai virions. A protein kinase activity has been found associated with purified Sendai virions. Most of the virion proteins and exogenous protamine served as substrates for this enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359304"}
{"pmid": "4359306", "title": "Diagnosis of adrenal hypertensions.", "content": "Diagnosis of adrenal hypertensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359306"}
{"pmid": "4359308", "title": "Change in baroreceptor sensitivity by angiotensin.", "content": "Change in baroreceptor sensitivity by angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359308"}
{"pmid": "4359307", "title": "Augmentation of pressor response to exogenous renin in rats with acute mercuric chloride intoxication: failure to demonstrate renin activating princile (s) in plasma.", "content": "Augmentation of pressor response to exogenous renin in rats with acute mercuric chloride intoxication: failure to demonstrate renin activating princile (s) in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359307"}
{"pmid": "4359302", "title": "Murine virus-induced proteins synthesized by hamster tumor cells transformed by, but not producing, murine sarcoma virus.", "content": "Murine virus-induced proteins synthesized by hamster tumor cells transformed by, but not producing, murine sarcoma virus. The 8303 hamster tumor cells transformed by Moloney strain of murine sarcoma virus (M-MSV), but which do not produce virus, do contain murine virus-induced proteins. The virus-induced proteins within the cell were identified either as free proteins or in association with membranous material, including the plasma membrane. In addition, some were excreted by the 8303 hamster tumor cells into the growth medium. Most virus-induced proteins were larger than 68,000 daltons, and they did not dissociate into components of smaller size in the presence of detergent and a reducing agent. A small amount of virus-induced protein with a molecular weight of less than 20,000 was also found in the hamster tumor cells. No virus-specific proteins with the identical antigenic specificity or size of the major internal group specific antigen (molecular weight about 30,000) of the murine leukemia viruses were present in these cells. There is a common cell surface antigen present in three other tumor cell lines, both virus-producing and non-virus-producing, identical in reactivity to that of the murine virus-induced antigen of the 8303 hamster tumor cell. This antigen is not present on the cell surface of normal mouse embryo cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359302"}
{"pmid": "4359310", "title": "Effects of cyclic AMP and dibutyryl cyclic AMP on renin release in vivo and in vitro.", "content": "Effects of cyclic AMP and dibutyryl cyclic AMP on renin release in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359310"}
{"pmid": "4359311", "title": "Lysosomal enzyme activities in rat kidney treated with DOCA, especially with reference to renin, cathepsin and beta-glucuronidase.", "content": "Lysosomal enzyme activities in rat kidney treated with DOCA, especially with reference to renin, cathepsin and beta-glucuronidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359311"}
{"pmid": "4359309", "title": "Metabolism of vasoactive substances in the lung.", "content": "Metabolism of vasoactive substances in the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359309"}
{"pmid": "4359312", "title": "Granular cell tumour in a male breast.", "content": "Granular cell tumour in a male breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359312"}
{"pmid": "4359314", "title": "Formation of steroid conjugates in the human. I. Biosynthesis of uridine diphosphate glucuronic acid.", "content": "Formation of steroid conjugates in the human. I. Biosynthesis of uridine diphosphate glucuronic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359314"}
{"pmid": "4359316", "title": "Research still holds the answer.", "content": "Research still holds the answer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359316"}
{"pmid": "4359315", "title": "Mechanism of action of glucocorticoids.", "content": "Mechanism of action of glucocorticoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359315"}
{"pmid": "4359320", "title": "Editorial: Cat leukemia: a threat to man?", "content": "Editorial: Cat leukemia: a threat to man?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359320"}
{"pmid": "4359317", "title": "Extended observations on the secretion of an influenza virus inhibitor in the colostrum of a Caucasian donor.", "content": "Extended observations on the secretion of an influenza virus inhibitor in the colostrum of a Caucasian donor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359317"}
{"pmid": "4359318", "title": "Effect of distilled water, hypertonic saline, freezing and freeze-drying on the haemagglutinin and haemolytic properties of Sendai virus.", "content": "Effect of distilled water, hypertonic saline, freezing and freeze-drying on the haemagglutinin and haemolytic properties of Sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359318"}
{"pmid": "4359324", "title": "Case reports. Benign renal tumor in a 16-month-old boy treated with pre-operative radiotherapy.", "content": "Case reports. Benign renal tumor in a 16-month-old boy treated with pre-operative radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359324"}
{"pmid": "4359325", "title": "Restoration of the conversion of desmosterol to cholesterol in L-cells after hybridization with human fibroblasts.", "content": "Restoration of the conversion of desmosterol to cholesterol in L-cells after hybridization with human fibroblasts. Hybrids between different human cells (which synthesize cholesterol) and mouse cells (whose end-product of sterol synthesis is desmosterol) were analyzed for the ability to convert desmosterol to cholesterol. Conversion of [(14)C]desmosterol to cholesterol and incorporation of [(14)C]acetate into the end-product sterol were studied in the parental and hybrid cells. Concordant segregation of the conversion of desmosterol to cholesterol and the human chromosome F-20 was observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359325"}
{"pmid": "4359328", "title": "Interferon induction by synthetic polynucleotides: importance of purine N-7 and strandwise rearrangement.", "content": "Interferon induction by synthetic polynucleotides: importance of purine N-7 and strandwise rearrangement. The antiviral activity and interferon-inducing ability of single-, double-, and triple-stranded polynucleotides, modified at pyrimidine C-5 or purine N-7, were evaluated in primary rabbit kidney cells challenged with vesicular stomatitis virus. (1) There is a parallel increase in antiviral activity and the temperature at which double-stranded polynucleotides rearrange to inactive triple-stranded complexes. (2) When the purine N-7 of (A)(n) is replaced by CH, all resulting double-stranded complexes fail to provide antiviral protection or to induce interferon, even though such complexes meet all requirements previously recognized for interferon induction. (3) Competition experiments between inactive and active polynucleotides indicate that single-stranded polynucleotides apparently do not bind to the cellular receptor sites for interferon induction, whereas triple-stranded complexes and inactive double-stranded complexes bind to such receptor sites but, probably for conformational reasons, fail to trigger the necessary message for interferon induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359328"}
{"pmid": "4359329", "title": "Transformation of cultured mammalian cells by viable herpes simplex virus subtypes 1 and 2.", "content": "Transformation of cultured mammalian cells by viable herpes simplex virus subtypes 1 and 2. A continuous line of rodent cells carrying the genome of the Rous sarcoma virus was stably transformed by exposure to viable herpes simplex virus of either subtype 1 or 2. Transformation was accompanied by alteration of morphology, growth characteristics, acquisition of a thymidine kinase activity (EC 2.7.1.21) resembling the corresponding specific activity of the enzyme in the herpes simplex virus, and capacity to express continuously some antigens specific for herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359329"}
{"pmid": "4359327", "title": "Interruption of the sequential release of small and large molecules from tumor cells by low temperature during cytolysis mediated by immune T-cells or complement.", "content": "Interruption of the sequential release of small and large molecules from tumor cells by low temperature during cytolysis mediated by immune T-cells or complement. Specific lysis of tumor cells by thymus-derived lymphocytes from alloimmunized mice (T-effector specific lysis) was studied with target cells labeled with isotopes attached to both small ((14)C-labeled nicotinamide) and large ((51)Cr-labeled) molecules. The results confirm and extend previous reports that target cells release small molecules considerably earlier than large molecules during T-effector specific lysis. After interruption of T-effector specific lysis by specific antibody and complement directed against the killer cells, or by ethylenediaminetetraacetic acid, release of both isotopes continued, eventually reaching identical levels of specific release, the value of which represents the fraction of the target cell population which had been committed to die at the time these treatments were applied. On the other hand, release of both isotopes during T-effector specific lysis stops immediately when the cultures are cooled to 0 degrees . Thus, while ethylenediaminetetraacetic acid or specific complement-mediated lysis of the killer cells merely prevents the initiation of any new damage to target cells, cooling to 0 degrees also stops the lytic process in already-damaged target cells. The colloid osmotic phase of target cell lysis induced by specific antibody and complement was similarly stopped at 0 degrees in tumor cells, but not in erythrocytes. Thus, in tumor target cells, both T-effector specific lysis and complement cause a sequential release of progressively larger molecules which can be immediately stopped at any point by cooling to 0 degrees .", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359327"}
{"pmid": "4359326", "title": "Evidence that the AKR murine-leukemia-virus genome is complete in DNA of the high-virus AKR mouse and incomplete in the DNA of the \"virus-negative\" NIH mouse.", "content": "Evidence that the AKR murine-leukemia-virus genome is complete in DNA of the high-virus AKR mouse and incomplete in the DNA of the \"virus-negative\" NIH mouse. The AKR mouse has a high titer of murine leukemia virus early in life, and virus-negative cells derived from embryos of this mouse strain can be activated to yield murine leukemia virus by treatment with 5-iododeoxyuridine. In contrast to this high-virus strain, the NIH Swiss mouse has a low incidence of leukemia and no murine leukemia virus has been isolated from it (virus-negative). We have investigated this difference between AKR and NIH mice by examining the sequences specific for murine leukemia virus in nucleic acids of these mice. A single-stranded viral-DNA probe synthesized in vitro using murine-leukemia-virus from the AKR mouse contains at least 87% of the sequences present in the 70S viral RNA; most of these sequences are in proportions similar to their content in the 70S RNA. Using this probe in nucleic acid hybridization experiments, we have shown that NIH-mouse-cell DNA and AKR-mouse-cell DNA differ with respect to sequences specific for AKR murine-leukemia-virus: NIH-mouse-cell DNA lacks some of the virus-specific sequences present in AKR-mouse-cell DNA, and there are two distinct sets of virus-specific sequences in AKR-mouse-cell DNA, whereas there is only one set in NIH-mouse-cell DNA.RNA from virus-negative AKR-mouse cells grown in tissue culture contains some, but not all, virus-specific RNA sequences; however, within 48 hr after initiating treatment of these cells with 5-iododeoxyuridine, the complete viral genome is represented in cellular RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359326"}
{"pmid": "4359330", "title": "Collagen biosynthesis in nonfibroblastic cell lines.", "content": "Collagen biosynthesis in nonfibroblastic cell lines. Prolyl hydroxylase and other enzymes of collagen synthesis have been found in cloned cells, including epithelium, melanoma, liver, HeLa, pituitary, kidney, and neuroblastoma. The significance of collagen biosynthesis in nonfibroblastic cells lines is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359330"}
{"pmid": "4359332", "title": "Penetration of mouse fibroblasts by the 5'-phosphate of 9-beta-D-arabinofuranosyladenine and incorporation of the nucleotide into DNA.", "content": "Penetration of mouse fibroblasts by the 5'-phosphate of 9-beta-D-arabinofuranosyladenine and incorporation of the nucleotide into DNA. 9-beta-D-Arabinofuranosyladenine 5'-monophosphate (araAMP) is more lethal to mouse fibroblasts (L cells) than the identical exogenous concentration of 9-beta-D-arabinofuranosyladenine (araA) (Cancer Res. 32, 1512, 1972). [(3)H,(32)P]AraAMP (0.1 mM) was taken into L cells for 4 hr in the presence of a large excess of (32)P(i). The radioactivity was subsequently found mainly in the adenine nucleotides in the acid-soluble fraction and in the cell DNA. The cellular concentration of 9-beta-D-arabinofuranosyladenine 5'-triphosphate (araATP) exceeded 2 muM. More than 90% of the (3)H was associated with araA in the nucleotides. After degradation of the adenine-containing triphosphates with apyrase, the adenine mononucleotides were separated by thin-layer electrophoresis and chromatography. All of the (32)P and 97% of the (3)H were associated with araAMP. The small amounts of (3)H and (32)P in the acid-insoluble material were similar during a 4 hr incubation. The DNA fraction was degraded enzymatically to 5'-mononucleotides. Both (32)P and (3)H were associated predominantly with 5'-dAMP. Most of the (3)H was in araA, detected after dephosphorylation. Enzymatic degradation of the DNA fraction to 3'-mononucleotides and fractionation revealed (3)H primarily in the 3'-adenine nucleotide and (32)P in each of the deoxynucleoside 3'-monophosphates. After dephosphorylation of the 3'-mononucleotides, 93% of the (3)H was found in araA. These results suggest that small amounts of araAMP penetrated the cell as an intact nucleotide, were further phosphorylated to the triphosphate, and subsequently incorporated in internucleotide linkage into DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359332"}
{"pmid": "4359331", "title": "Effects of guanosine tetraphosphate, guanosine pentaphosphate, and beta-gamma methylenyl-guanosine pentaphosphate on gene expression of Escherichia coli in vitro.", "content": "Effects of guanosine tetraphosphate, guanosine pentaphosphate, and beta-gamma methylenyl-guanosine pentaphosphate on gene expression of Escherichia coli in vitro. The effects of guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), both produced by E. coli, were measured on the activities of several genes in a cell-free system. Gene activity is measured as gene-directed synthesis of biochemically competent protein or transfer RNA. Both ppGpp and pppGpp stimulated the activities of the ara, lac, and trp operons and inhibited the arg operon. Production of transfer-RNA(Tyr) was unaffected by moderate levels of either ppGpp or pppGpp and only slightly inhibited at higher levels of ppGpp. Since the cell-free reaction mixtures hydrolyze pppGpp to ppGpp, we performed similar studies with a hydrolysis-resistant analog of pppGpp, the beta-gamma methylenyl derivative (pcppGpp). In general, pcppGpp shows the same inhibitory potency as pppGpp for the arg operon, but lacks the stimulatory effects on the ara, lac, and trp operons. This result suggests that the stimulation of these gene activities is specific for ppGpp.Under similar conditions, pppGpp and ppGpp show a slight inhibitory effect on the messenger-directed synthesis of beta-galactosidase and no effect on the messenger-directed synthesis of MS2 viral-coat protein. These observations, together with the fact that in the same system these nucleotides affect coupled transcription and translation, lead us to surmise that the activities of pppGpp and ppGpp are exerted at the level of RNA polymerase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359331"}
{"pmid": "4359333", "title": "ACTH antagonists.", "content": "ACTH antagonists. Structural modifications within the active site of the ACTH molecule have produced analogs that inhibit the hormone sensitive adenylate cyclase system of bovine adrenal cortical plasma membranes. It is demonstrated that the tryptophan residue of the ACTH molecule is essential for stimulation of the enzyme. Substitution of tryptophan by phenylalanine or by N(alpha)-methyltryptophan as in [Gln(5), Phe(9)]corticotropin(1-20) amide or [N(alpha)-Metrp(9)]corticotropin(1-24) provides ACTH analogs that exhibit high affinity for the ACTH receptor(s) but fail to activate the adenylate cyclase system. It is concluded that affinity for the receptors alone is not sufficient for expression of hormonal activity. The observation that adrenal cortical adenylate cyclase activated by fluoride ion is not inhibited by the antagonists indicates that hormonal and fluoride activation proceed via different mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359333"}
{"pmid": "4359335", "title": "Kinetics of early changes in phosphate and uridine transport and cyclic AMP levels stimulated by serum in density-inhibited 3T3 cells.", "content": "Kinetics of early changes in phosphate and uridine transport and cyclic AMP levels stimulated by serum in density-inhibited 3T3 cells. A kinetic study of the early changes in uridine- and phosphate-transport rates and 3':5'-cyclic AMP levels induced by the addition of serum to quiescent 3T3 cells revealed that the increase in phosphate uptake and the decrease in the intracellular concentration of 3':5'-cyclic AMP immediately follow the addition of serum. In contrast, the increase in uridine transport occurred after a lag of several minutes and was clearly preceded by the other changes. The activation of phosphate transport involved an increase in V(max), while a more complex pattern was observed for uridine transport. A possible role of phosphate in connection with the other early events was also studied. The addition of phosphate to quiescent cells produced a time-dependent decrease in 3':5'-cyclic AMP levels and this ion was required for full activation of uridine transport by serum. The results show that the increase in phosphate transport is a primary event in the reinitiation of growth and suggest that the increase in phosphate transport may be connected with subsequent metabolic steps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359335"}
{"pmid": "4359334", "title": "Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture.", "content": "Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture. Chronic (5-16 hr) exposure of cultured human lymphocytes to 10(-8) M insulin at 37 degrees in vitro produced a decrease in insulin receptor concentrations unaccounted for by simple occupancy of sites; acute exposure (0-2 hr) was without effect. These results reproduced observations in vivo where chronic hyperinsulinemia (e.g., 10(-8) M insulin in the circulation of obese insulinresistant hyperglycemic mice) is associated with a substantial reduction in the concentration of insulin receptors per cell, while acute hyperinsulinemia in vivo has no effect on receptor concentration. These data suggest a reciprocal relationship between insulin in the extracellular fluid and the concentration of insulin receptors per cell, which is mediated at the target cell itself by intracellular insulin-sensitive regulatory processes and directly affects target-cell sensitivity to hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359334"}
{"pmid": "4359337", "title": "Granulocytes containing cytoplasmic inclusions in human tuberculous pleuritis.", "content": "Granulocytes containing cytoplasmic inclusions in human tuberculous pleuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359337"}
{"pmid": "4359338", "title": "Nonhistone chromosomal proteins and gene regulation.", "content": "Nonhistone chromosomal proteins and gene regulation. Evidence from several model systems suggests that nonhistone chromosomal proteins may regulate gene expression in eukaryotic cells. The data indicate that the synthesis of new species of nonhistone chromosomal proteins as well as modifications of preexisting nonhistone chromosomal proteins are involved in the control of transcription. However, from the vast number of proteins included in this class, it is apparent that, in addition to regulating the transcription of defined genome loci, the nonhistone chromosomal proteins include enzymes that have a general function, proteins that are involved in determining the structure of chromatin, as well as proteins that serve as recognition sites for binding of regulatory macromolecules. The presence of a nucleoplasmic pool of nonhistone chromosomal proteins which may exchange with the chromatin has also been reported (89). While it is clear that the nonhistone chromosomal proteins play a key role in the regulation of gene expression, the exact manner in which they interact with the genome to initiate, modify, or augment the transcription of specific RNA molecules remains to be resolved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359338"}
{"pmid": "4359339", "title": "Amorphous semiconductor switching in melanins.", "content": "Amorphous semiconductor switching in melanins. Melanins produced synthetically and isolated from biological systems act as an amorphous semiconductor threshold switch. Switching occurs reversibly at potential gradients two to three orders of magnitude lower than reported for inorganic thin films, and comparable to gradients existing in some biological systems. Of a number of other biological materials tested, only cytochrome c acted similarly, but at the high potential gradients reported for thin film amorphous semiconductors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359339"}
{"pmid": "4359340", "title": "Hormonal control of neutrophil lysosomal enzyme release: effect of epinephrine on adenosine 3',5'-monophosphate.", "content": "Hormonal control of neutrophil lysosomal enzyme release: effect of epinephrine on adenosine 3',5'-monophosphate. Human neutrophilic leukocytes release neutral protease and beta-glucuronidase during cell contact with, and phagocytosis of, zymosan particles treated with rheumatoid arthritic serum. Release of lysosomal enzymes is inhibited by epinephrine and adenosine 3',5'-monophosphate (cyclic AMP), but not by phenylephrine or adenosine 5'-monophosphate. Inhibition of enzyme release by epinephrine may be mediated by cyclic AMP because the cyclic AMP in the neutrophils is increased by epinephrine treatment at the time when enzyme release is reduced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359340"}
{"pmid": "4359341", "title": "Hydrocortisone influences developing collaterals. 2. A cytochemical study.", "content": "Hydrocortisone influences developing collaterals. 2. A cytochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359341"}
{"pmid": "4359344", "title": "A new sensor for pneumatic tonometry. Construction and working principle.", "content": "A new sensor for pneumatic tonometry. Construction and working principle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359344"}
{"pmid": "4359343", "title": "Clinical evaluation of the luteinizing hormone-releasing hormone (LH-RH) test in cases with anatomically verified disorders of the hypothalamo-pituitary region.", "content": "Clinical evaluation of the luteinizing hormone-releasing hormone (LH-RH) test in cases with anatomically verified disorders of the hypothalamo-pituitary region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359343"}
{"pmid": "4359345", "title": "Trabeculotomy ab externo.", "content": "Trabeculotomy ab externo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359345"}
{"pmid": "4359346", "title": "The heredity of glaucoma.", "content": "The heredity of glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359346"}
{"pmid": "4359347", "title": "Trabeculotomy, trabeculectomy and sinusotomy--some clinical results.", "content": "Trabeculotomy, trabeculectomy and sinusotomy--some clinical results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359347"}
{"pmid": "4359348", "title": "Adrenalin therapy in glaucoma.", "content": "Adrenalin therapy in glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359348"}
{"pmid": "4359349", "title": "Experience with keratoprostheses.", "content": "Experience with keratoprostheses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359349"}
{"pmid": "4359351", "title": "Ophthalmological involvements in diabetes. An introduction.", "content": "Ophthalmological involvements in diabetes. An introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359351"}
{"pmid": "4359350", "title": "Clinical and histological findings in crystalline corneal dystrophy.", "content": "Clinical and histological findings in crystalline corneal dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359350"}
{"pmid": "4359336", "title": "Peripheral versus central mechanisms accounting for antianxiety effects of propranolol.", "content": "Peripheral versus central mechanisms accounting for antianxiety effects of propranolol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359336"}
{"pmid": "4359353", "title": "Pigment granules in iris pigment epithelium of diabetics.", "content": "Pigment granules in iris pigment epithelium of diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359353"}
{"pmid": "4359352", "title": "Pregnancy and diabetic retinopathy.", "content": "Pregnancy and diabetic retinopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359352"}
{"pmid": "4359354", "title": "Follow-up of initially nonglaucomatous patients with fibrillopathia epitheliocapsularis (so-called senile exfoliation of the anterior lens capsule).", "content": "Follow-up of initially nonglaucomatous patients with fibrillopathia epitheliocapsularis (so-called senile exfoliation of the anterior lens capsule).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359354"}
{"pmid": "4359356", "title": "Importance of callosal transfer in the extramacular inhibition phenomenon along the hemiopic border.", "content": "Importance of callosal transfer in the extramacular inhibition phenomenon along the hemiopic border.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359356"}
{"pmid": "4359355", "title": "The intraocular pressure. An introduction.", "content": "The intraocular pressure. An introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359355"}
{"pmid": "4359357", "title": "Experiences in surgical treatment of haemorrhagic glaucoma. A follow-up study.", "content": "Experiences in surgical treatment of haemorrhagic glaucoma. A follow-up study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359357"}
{"pmid": "4359359", "title": "Newer respiratory viruses: their role in respiratory illness of children.", "content": "Newer respiratory viruses: their role in respiratory illness of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359359"}
{"pmid": "4359358", "title": "Reflex organization and contraction properties of facial muscles. An experimental study in the cat.", "content": "Reflex organization and contraction properties of facial muscles. An experimental study in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359358"}
{"pmid": "4359364", "title": "Human memory and the cholinergic system. A relationship to aging?", "content": "Human memory and the cholinergic system. A relationship to aging?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359364"}
{"pmid": "4359365", "title": "Amyotrophic lateral sclerosis. Abnormal cellular inflammatory response.", "content": "Amyotrophic lateral sclerosis. Abnormal cellular inflammatory response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359365"}
{"pmid": "4359366", "title": "Hepatoma in Papua New Guinea.", "content": "Hepatoma in Papua New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359366"}
{"pmid": "4359368", "title": "Assembly of tobacco mosaic virus rods in vitro. Elongation of partially assembled rods.", "content": "Assembly of tobacco mosaic virus rods in vitro. Elongation of partially assembled rods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359368"}
{"pmid": "4359367", "title": "Cutaneous amoebiasis.", "content": "Cutaneous amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359367"}
{"pmid": "4359369", "title": "Selenium as a catalyst for the reduction of cytochrome c by glutathione.", "content": "Selenium as a catalyst for the reduction of cytochrome c by glutathione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359369"}
{"pmid": "4359371", "title": "Instability of the uterine estrogen receptor under in vitro conditions.", "content": "Instability of the uterine estrogen receptor under in vitro conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359371"}
{"pmid": "4359370", "title": "Estrophilic binding sites of the uterus. Relation to uptake and retention of estradiol in vitro.", "content": "Estrophilic binding sites of the uterus. Relation to uptake and retention of estradiol in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359370"}
{"pmid": "4359372", "title": "Interaction of ovarian receptors with human luteinizing hormone and human chorionic gonadotropin.", "content": "Interaction of ovarian receptors with human luteinizing hormone and human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359372"}
{"pmid": "4359373", "title": "Excited states and reactivity of 5-deazaflavine. Comparative studies with flavine.", "content": "Excited states and reactivity of 5-deazaflavine. Comparative studies with flavine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359373"}
{"pmid": "4359374", "title": "Estimate of minimal distance between rapidly exchanging zinc and nucleotide binding sites in liver alcohol dehydrogenase.", "content": "Estimate of minimal distance between rapidly exchanging zinc and nucleotide binding sites in liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359374"}
{"pmid": "4359376", "title": "The function of the descending root of the fifth nerve.", "content": "The function of the descending root of the fifth nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359376"}
{"pmid": "4359375", "title": "Deuterium isotope effects on initial rates of the liver alcohol dehydrogenase reaction.", "content": "Deuterium isotope effects on initial rates of the liver alcohol dehydrogenase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359375"}
{"pmid": "4359377", "title": "Cytoplasmic inclusions in the vermiform appendix and skeletal muscle in two types of so-called neuronal ceroid-lipofuscinosis.", "content": "Cytoplasmic inclusions in the vermiform appendix and skeletal muscle in two types of so-called neuronal ceroid-lipofuscinosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359377"}
{"pmid": "4359378", "title": "Evolutionary perspectives on the function of the optic tectum.", "content": "Evolutionary perspectives on the function of the optic tectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359378"}
{"pmid": "4359379", "title": "Mouse leukemia virus growth in mouse cells contaminated with Mycoplasma.", "content": "Mouse leukemia virus growth in mouse cells contaminated with Mycoplasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359379"}
{"pmid": "4359380", "title": "Isolation and chemical characterization of mucopolysaccharides from rat tumors.", "content": "Isolation and chemical characterization of mucopolysaccharides from rat tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359380"}
{"pmid": "4359381", "title": "Effects of hexosamines and their acetyl derivatives on aggregation of rat hepatoma cells in rotation culture.", "content": "Effects of hexosamines and their acetyl derivatives on aggregation of rat hepatoma cells in rotation culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359381"}
{"pmid": "4359382", "title": "Studies of initiation factors in protein synthesis of host liver and transplantable hepatoma.", "content": "Studies of initiation factors in protein synthesis of host liver and transplantable hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359382"}
{"pmid": "4359383", "title": "Two-dimensional gel electrophoresis of acid-extractable nuclear proteins of regenerating and thioacetamide-treated rat liver, Morris 9618a hepatoma, and Walker 256 carcinosarcoma.", "content": "Two-dimensional gel electrophoresis of acid-extractable nuclear proteins of regenerating and thioacetamide-treated rat liver, Morris 9618a hepatoma, and Walker 256 carcinosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359383"}
{"pmid": "4359384", "title": "Recent studies on the formation of cerebrospinal fluid.", "content": "Recent studies on the formation of cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359384"}
{"pmid": "4359385", "title": "Symmetrical epileptogenic foci in cerebral cortex of immature rat.", "content": "Symmetrical epileptogenic foci in cerebral cortex of immature rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359385"}
{"pmid": "4359386", "title": "Phenylalanyl-tRNA synthetase from Escherichia coli K10. Synergistic coupling between the sites for binding of L-phenylalanine and ATP.", "content": "Phenylalanyl-tRNA synthetase from Escherichia coli K10. Synergistic coupling between the sites for binding of L-phenylalanine and ATP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359386"}
{"pmid": "4359387", "title": "The wall peptidoglycans of Neisseria perflava, Moraxella glucidolytica, Pseudomonas alcaligenes and Proteus vulgaris strain P18.", "content": "The wall peptidoglycans of Neisseria perflava, Moraxella glucidolytica, Pseudomonas alcaligenes and Proteus vulgaris strain P18.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359387"}
{"pmid": "4359388", "title": "Products of mitochondrial protein synthesis in Neurospora crassa. Determination of equimolar amounts of three products in cytochrome oxidase on the basis of amino-acid analysis.", "content": "Products of mitochondrial protein synthesis in Neurospora crassa. Determination of equimolar amounts of three products in cytochrome oxidase on the basis of amino-acid analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359388"}
{"pmid": "4359389", "title": "The covalent structure of collagen. 1. The chymotrypsin, trypsin, and thermolysin-derived peptides of alpha1-CB7 from calf-skin collagen.", "content": "The covalent structure of collagen. 1. The chymotrypsin, trypsin, and thermolysin-derived peptides of alpha1-CB7 from calf-skin collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359389"}
{"pmid": "4359390", "title": "The covalent structure of collagen. 2. The amino-acid sequence of alpha1-CB7 from calf-skin collagen.", "content": "The covalent structure of collagen. 2. The amino-acid sequence of alpha1-CB7 from calf-skin collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359390"}
{"pmid": "4359391", "title": "Cirrhosis and heterozygous FZ alpha1-antitrypsin deficiency in an adult. Case report and review of the literature.", "content": "Cirrhosis and heterozygous FZ alpha1-antitrypsin deficiency in an adult. Case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359391"}
{"pmid": "4359392", "title": "Mechanisms and control of secretion of bile water and electrolytes.", "content": "Mechanisms and control of secretion of bile water and electrolytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359392"}
{"pmid": "4359393", "title": "Progressive enzyme studies on spontaneous hepatocarcinogenesis in reciprocal F1 crosses of C3H (JAX) and ICRC strains.", "content": "Progressive enzyme studies on spontaneous hepatocarcinogenesis in reciprocal F1 crosses of C3H (JAX) and ICRC strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359393"}
{"pmid": "4359394", "title": "Carcinoma of the lung--a correlative cytological and histopathological study.", "content": "Carcinoma of the lung--a correlative cytological and histopathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359394"}
{"pmid": "4359396", "title": "Melanoameloblastoma--report of a case and review of literature.", "content": "Melanoameloblastoma--report of a case and review of literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359396"}
{"pmid": "4359395", "title": "Mixed salivary tumours.", "content": "Mixed salivary tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359395"}
{"pmid": "4359397", "title": "The application of ultrasound tomography in radiation therapy.", "content": "The application of ultrasound tomography in radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359397"}
{"pmid": "4359398", "title": "A case report on calcified mucinous adenocarcinoma of the stomach.", "content": "A case report on calcified mucinous adenocarcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359398"}
{"pmid": "4359400", "title": "Genetic influences affecting the occurrence of a diabetes mellitus-like disease in mice infected with the encephalomyocarditis virus.", "content": "Genetic influences affecting the occurrence of a diabetes mellitus-like disease in mice infected with the encephalomyocarditis virus. The M variant of encephalomyocarditis virus produces a diabetes mellitus-like disease in DBA/2 mice but not in animals of the C3H strain. Fewer than one-third of infected F(1) (DBA/2 x C3H) progeny exhibit the disease, whereas the prevalence in backcrosses (F(1) x DBA/2, F(1) x C3H) is comparable to the parental inbred strain. Thus, the mode of inheritance of the diabetic predisposition appears to be polygenic. DBA/2 animals develop striking inflammatory and necrotizing lesions of the islets of Langerhans; in contrast, alterations of the insular tissue in the C3H mice are minimal. Although metabolic abnormalities appear to be consequent to lesions of beta cells, the factors influencing the severity of these insular changes are incompletely understood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359400"}
{"pmid": "4359399", "title": "Renal hypertension in rats immunized against angiotensin I and angiotensin II.", "content": "Renal hypertension in rats immunized against angiotensin I and angiotensin II. Rats, actively immunized against angiotensin I (AI) and angiotensin II (AII), were subjected to unilateral renal artery constriction to determine whether the resulting hypertension, which may still ensue in the animal immunized against AII, could be prevented by such combined immunity. Sustained immunity to both AI and AII neither changed preoperative blood pressures of the rats from those of control mock-immunized rats nor altered the incidence or severity of renal dip hypertension. Vascular hyperresponsiveness to small quantities of free angiotensin could not be invoked to explain the hypertension, for there was no significant difference between mock-immunized hypertensive animals, and those remaining normotensive, regarding pressor sensitivity to intravenous AI, AII, renin, and norepinephrine. (AI + AII)-immunized hypertensive rats required AI doses averaging 260 times greater than nonimmune hypertensives to elicit equipressor responses, and were refractory to renin, but not to norepinephrine. Thus, while previous studies have not excluded direct participation of endogenous AI in renal clip hypertension in rats, evidence from our experiments makes it extremely difficult to sustain any pressor function therein for circulating AI or AII. Our results also preclude involvement of AII produced from circulating AI by conversion within arteriolar walls, close to receptor sites, since AI immunity would block this mechanism of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359399"}
{"pmid": "4359401", "title": "Cell transformation by viruses and the role of viruses in cancer. The eleventh Marjory Stephenson Memorial Lecture.", "content": "Cell transformation by viruses and the role of viruses in cancer. The eleventh Marjory Stephenson Memorial Lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359401"}
{"pmid": "4359402", "title": "Cell-mediated immunity to herpes simplex virus in man.", "content": "Cell-mediated immunity to herpes simplex virus in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359402"}
{"pmid": "4359403", "title": "Guinea pig model for cutaneous herpes simplex virus infection.", "content": "Guinea pig model for cutaneous herpes simplex virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359403"}
{"pmid": "4359404", "title": "Viral studies in pemphigus.", "content": "Viral studies in pemphigus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359404"}
{"pmid": "4359405", "title": "The mechanism of drug-induced erythrocyte vacuole formation.", "content": "The mechanism of drug-induced erythrocyte vacuole formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359405"}
{"pmid": "4359406", "title": "The influence of dietary potassium on the renin and aldosterone response to diuretic-induced volume depletion.", "content": "The influence of dietary potassium on the renin and aldosterone response to diuretic-induced volume depletion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359406"}
{"pmid": "4359407", "title": "Glomerular glycoprotein: galactosyl transferase activity in rat kidney.", "content": "Glomerular glycoprotein: galactosyl transferase activity in rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359407"}
{"pmid": "4359409", "title": "Biologically active components from mycobacterial cell walls. II. Suppression and regression of strain-2 guinea pig hepatoma.", "content": "Biologically active components from mycobacterial cell walls. II. Suppression and regression of strain-2 guinea pig hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359409"}
{"pmid": "4359408", "title": "Lack of effect of erythropoietin on cyclic adenosine-3',5'-monophosphate levels in rat fetal liver cells.", "content": "Lack of effect of erythropoietin on cyclic adenosine-3',5'-monophosphate levels in rat fetal liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359408"}
{"pmid": "4359410", "title": "Autogenous immunity to endogenous RNA tumor virus: chronic humoral immune response to virus envelope antigens in B6C3F1 mice.", "content": "Autogenous immunity to endogenous RNA tumor virus: chronic humoral immune response to virus envelope antigens in B6C3F1 mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359410"}
{"pmid": "4359412", "title": "Neoplastic transformation in vivo and in vitro of regenerating hamster hepatic cells by oncogenic DNA Simian virus 40.", "content": "Neoplastic transformation in vivo and in vitro of regenerating hamster hepatic cells by oncogenic DNA Simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359412"}
{"pmid": "4359411", "title": "Rat alpha1 fetoprotein. IV. Effect of growth and surgical removal of Morris hepatoma 7777 on the serum alpha1F concentration of Buffalo rats.", "content": "Rat alpha1 fetoprotein. IV. Effect of growth and surgical removal of Morris hepatoma 7777 on the serum alpha1F concentration of Buffalo rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359411"}
{"pmid": "4359413", "title": "Differential inhibition by fucoses of aggregation of rat hepatoma cells in rotation-mediated cell cultures.", "content": "Differential inhibition by fucoses of aggregation of rat hepatoma cells in rotation-mediated cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359413"}
{"pmid": "4359415", "title": "Familial medullary thyroid carcinoma and pheochromocytoma: epidemiologic investigations.", "content": "Familial medullary thyroid carcinoma and pheochromocytoma: epidemiologic investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359415"}
{"pmid": "4359414", "title": "Associations between tumor types in a large-scale carcinogenesis study of CF-1 mice.", "content": "Associations between tumor types in a large-scale carcinogenesis study of CF-1 mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359414"}
{"pmid": "4359417", "title": "Development of leukemia in rats with tumors induced by chicken sarcoma virus.", "content": "Development of leukemia in rats with tumors induced by chicken sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359417"}
{"pmid": "4359416", "title": "Coexistence of particles resembling herpesvirus and type-C virus in feather follicle epithelium of chickens.", "content": "Coexistence of particles resembling herpesvirus and type-C virus in feather follicle epithelium of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359416"}
{"pmid": "4359418", "title": "Sendai virion transcriptase complex: polyeptide composition and inhibition by virion envelope proteins.", "content": "Sendai virion transcriptase complex: polyeptide composition and inhibition by virion envelope proteins. Sendai virions, disrupted in 2% Triton X-100 in 1 M KCl, were separated into nucleocapsids and envelope proteins by centrifugation. The nucleocapsids, representing 46% of the virion proteins, had a buoyant density of 1.29 gm/cm(3) in D(2)O sucrose. RNA-dependent transcriptase activity associated with them had a ninefold greater specific activity than transcriptase assayed in unfractionated detergent-disrupted virions. These enzyme-active nucleocapsids contained only two polypeptides, the largest virion polypeptide (molecular weight 75,000) and the nucleocapsid structure unit (molecular weight 60,000). Virion envelope proteins, either glycoproteins or nonglycosylated matrix protein, inhibited nucleocapsid-associated polymerase activity; brief heat denaturation abolished their inhibitory activity. Yeast RNA stimulated nucleocapsid-associated enzyme, suggesting that stimulatory polyanions act at the enzyme-template level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359418"}
{"pmid": "4359420", "title": "In vitro polyoma DNA synthesis: characterization of a system from infected 3T3 cells.", "content": "In vitro polyoma DNA synthesis: characterization of a system from infected 3T3 cells. A lysate from hypotonically swollen polyoma-infected BALB/3T3 cells incorporated labeled deoxynucleotide triphosphates into both viral and cellular DNAs. The incorporation was stimulated by the presence of ATP, deoxynucleotide triphosphates, thiols, and magnesium ions. Strong inhibition of incorporation was observed with thiol reagents and arabinosyl nucleotide triphosphates. The rate of in vitro synthesis increased with the temperature of incubation as expected. Incorporation into cellular DNA for up to 2 h was observed in lysates from virus-infected and serum-stimulated cells but not from resting cells. Synthesis in the system, therefore, appeared to reflect the physiological state of the cells before preparation of the lysate. Incorporation into viral DNA stopped far sooner than that into cellular DNA. During the initial phase of the in vitro incubation, incorporation occurred into viral replicative intermediates (RI). These RIs had identical properties to those isolated after in vivo pulse labeling and a substantial proportion of them was matured to form I DNA at later times in the incubation through all the stages known to occur in vivo. Density labeling of the in vitro product showed that practically all of the RIs pre-existing in the infected cell took part in the in vitro reaction. Analysis of DNA labeled in vitro in the presence of 5-bromodeoxyuridine triphosphate showed that synthesis occurred on RIs at all stages of replication and that the progeny strands were elongated by up to 80% of unit viral DNA length. Pre-existing RIs, pulse labeled in vivo, showed evidence of a pool at a late stage of replication which required elongation of their progeny strands by approximately 25% during conversion to form I molecules. From density-labeling experiments, we were also able to show that viral DNA synthesis in vitro was semiconservative. The major reason for cessation of viral DNA synthesis in vitro was the very limited ability of the lysate to initiate new rounds of viral DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359420"}
{"pmid": "4359419", "title": "Protein kinase and phosphoproteins of vesicular stomatitis virus.", "content": "Protein kinase and phosphoproteins of vesicular stomatitis virus. Protein kinases of similar but not identical activity were found associated with vesicular stomatitis (VS) virions grown in mouse L cells, primary chicken embryo (CE) cells, and BHK-21 cells, as well as being present in VS virions grown in HeLa and Aedes albopictus cells. The virion kinase preferentially phosphorylated the nucleocapsid NS protein in vitro and to a lesser extent the envelope M protein. Other virion proteins were phosphorylated in vitro only after drastic detergent treatment. Partial evidence that the virion kinase is of cellular origin was obtained by finding reduced enzyme activity in virions released from cells pretreated with actinomycin D and cycloheximide. Selective detergent and detergent-salt fractionation of VS virions revealed that the kinase activity was present in the envelope but not the spikes. The virion kinase activity in a Triton-salt-solubilized envelope fraction could be separated from M and G proteins and partially purified by phosphocellulose column chromatography. Virions released from L, CE, and BHK-21 cells infected in the presence of [(32)P]orthophosphate were labeled almost exclusively in the NS protein. Both soluble and nucleocapsid-associated NS phosphoprotein were present in cytoplasmic extracts of VS viral-infected L cells. The origin and function of the NS phosphoprotein remain to be elucidated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359419"}
{"pmid": "4359421", "title": "Virus type-specific thymidine kinase in cells biochemically transformed by herpes simplex virus types 1 and 2.", "content": "Virus type-specific thymidine kinase in cells biochemically transformed by herpes simplex virus types 1 and 2. Transformation of mouse cells (Ltk(-)) and human cells (HeLa Bu) from a thymidine kinase (TK)-minus to a TK(+) phenotype (herpes simplex virus [HSV]-transformed cells) has been induced by infection with ultraviolet-irradiated HSV type 2 (HSV-2), as well as by HSV type 1 (HSV-1). Medium containing methotrexate, thymidine, adenine, guanosine, and glycine was used to select for cells able to utilize exogenous thymidine. We have determined the kinetics of thermal inactivation of TK from cells lytically infected with HSV-1 or HSV-2 and from HSV-1- and HSV-2-transformed cells. Three hours of incubation at 41 C produces a 20-fold decrease in the TK activity of cell extracts from HSV-2-transformed cells and Ltk(-) cells lytically infected with HSV-2. The same conditions produce only a twofold decrease in the TK activities from HSV-1-transformed cells and cells lytically infected with HSV-1. This finding supports the hypothesis that an HSV structural gene coding for TK has been incorporated in the HSV-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359421"}
{"pmid": "4359422", "title": "Endogenous C-type viruses of BALB-c cells: frequencies of spontaneous and chemical induction.", "content": "Endogenous C-type viruses of BALB-c cells: frequencies of spontaneous and chemical induction. A sensitive biological assay has been developed for studying the frequency of virus induction from mouse cells containing poorly infectious endogenous C-type viruses. A low spontaneous frequency of virus activation of one but not a second endogenous virus of BALB/c cells has been demonstrated. The resistance of BALB/c cells to superinfection by the more inducible virus appears to be absolute, whereas resistance to the other virus is only relative. Thus, the evidence indicates that the BALB/c cell exerts differential effects at two levels of regulation on the expression of its biologically distinguishable endogenous C-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359422"}
{"pmid": "4359424", "title": "Protein kinase stimulated by cyclic GMP in uninfected and simian virus 40-infected monkey kidney cells.", "content": "Protein kinase stimulated by cyclic GMP in uninfected and simian virus 40-infected monkey kidney cells. Uninfected African green monkey kidney cells contain a cyclic GMP-stimulated protein kinase. The level or specific activity of the enzyme was not significantly increased after infection of the cells with simian virus 40. This enzyme probably catalyzes the phosphorylation of the structural proteins of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359424"}
{"pmid": "4359423", "title": "Biochemical studies on the chi mutation of bacteriophage T4: differential inhibition of chi+ and chi DNA synthesis by mitomycin C.", "content": "Biochemical studies on the chi mutation of bacteriophage T4: differential inhibition of chi+ and chi DNA synthesis by mitomycin C. Biochemical studies were carried out to determine the effect of chi mutation on T4 DNA synthesis. The rate and final extent of DNA synthesis are almost the same with T4D- and T4chi-infected cells, although the burst size of T4chi is about one-sixth that of the wild type. The DNA synthesis of T4chi-infected cells is more readily inhibited by mitomycin C than is that of T4 wild type. When mitomycin C was added during active phage growth, DNA synthesis of T4chi halted almost immediately. T4 DNA polymerases isolated from chi(+)- and chi-infected cells, however, exhibit no difference with regard to their sensitivities to mitomycin C, priming activities with alkylated or ultraviolet light-irradiated templates and other enzymatic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359423"}
{"pmid": "4359425", "title": "In vitro polyoma DNA synthesis: studies on an early temperature-sensitive mutant.", "content": "In vitro polyoma DNA synthesis: studies on an early temperature-sensitive mutant. The polyoma ts-a function was investigated by using an in vitro DNA-synthesizing system. A comparison of systems derived from ts25 (a ts-a group mutant)-and ts1260 (a late group mutant)-infected cells showed that the activation energies for DNA chain elongation and the mechanisms of discontinous growth were identical for both mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359425"}
{"pmid": "4359426", "title": "Viruses of Entamoeba histolytica. V. Ultrastructure of the polyhedral virus V301.", "content": "Viruses of Entamoeba histolytica. V. Ultrastructure of the polyhedral virus V301. The polyhedral amoebal virus V(301) presents sectioned profiles consistent with its having icosahedral (532) symmetry. The DNA appears to be packed in an orderly, folded arrangement of lesser symmetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359426"}
{"pmid": "4359427", "title": "Detection of homologous RNA sequences among six rhabdovirus genomes.", "content": "Detection of homologous RNA sequences among six rhabdovirus genomes. Complete transcripts of the genome of vesicular stomatitis virus Indiana strain have been used to hybridize to virion RNA to determine if there is RNA sequence homology among these viruses. Cellular RNA from cells infected by each of these viruses has also been used for hybridization with the homologous or heterologous virion RNA. The results indicate that there is little exact sequence homology among these viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359427"}
{"pmid": "4359428", "title": "Location of the transcription defect in group I temperature-sensitive mutants of vesicular stomatitis virus.", "content": "Location of the transcription defect in group I temperature-sensitive mutants of vesicular stomatitis virus. The ribonucleoprotein-dependent RNA transcriptase in vesicular stomatitis B virions of four temperature-sensitive (ts) mutants belonging to complementation group I was analyzed in vitro at permissive (31 C) and restrictive (39 C) temperatures. The RNA-synthesizing activity of all four ts mutants was more labile at 39 C than was the transcriptive activity of wild-type (wt) virions. In order to locate the temperature-sensitive transcription defect in the mutants, wt and ts mutant virions were fractionated by Triton X-100-high salt solubilizer into a sedimentable ribonucleoprotein template and a nonsedimentable enzyme fraction, each of which alone had little or no transcriptive activity. The template- and enzyme-containing fractions of wt virions were then tested for their capacity to restore transcriptive activity at 39 C to corresponding template and enzyme preparations of ts mutant virions. Recombination of wt template and ts enzymes resulted in no significant restoration of capacity to synthesize RNA at restrictive temperature. In contrast, transcriptive function at 39 C was reconstituted by recombining the wt enzyme with the template component of ts mutants. It appears, therefore, that the enzyme, rather than the template, is the temperature-sensitive component of the transcription complex of group I vesicular stomatitis virus mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359428"}
{"pmid": "4359429", "title": "Analysis of minimal functions of simian virus 40. 3. Evidence for \"host cell repair\" of oncogenicity and infectivity of UV-irradiated simian virus 40.", "content": "Analysis of minimal functions of simian virus 40. 3. Evidence for \"host cell repair\" of oncogenicity and infectivity of UV-irradiated simian virus 40. The in vitro transforming capacity of simian virus 40 (SV40) for Syrian hamster cells is highly resistant to inactivation by UV light in comparison to infectivity. In the same cell system, we demonstrated a \"host cell repair mechanism\" sensitive to caffeine which is, to a large extent, responsible for the high resistance to UV inactivation of the transforming capacity of SV40. The survival of infectivity of UV-irradiated SV40 in CV-1 cells was also sensitive to caffeine, again indicating host cell repair. On the other hand, depression of normal cell DNA synthesis by hydroxyurea during the first 24 h postinfection only modestly reduced, and to a similar extent, the transforming capacity of UV-irradiated and nonirradiated SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359429"}
{"pmid": "4359430", "title": "Enzymatic radioiodination of the envelope proteins of avian myeloblastosis virus.", "content": "Enzymatic radioiodination of the envelope proteins of avian myeloblastosis virus. Purified avian myeloblastosis virus was iodinated by the lactoperoxidase method. Disruption of the labeled virions and chromatography of the viral proteins showed that radioiodine was associated only with the glycoproteins of the viral envelope. Reaction of the radiolabeled virus with antiviral antibody followed by mild detergent treatment and subsequent recovery of immune complexes showed this technique to be useful for the isolation of viral envelope antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359430"}
{"pmid": "4359431", "title": "Translation of vesicular stomatitis messenger RNA by extracts from mammalian and plant cells.", "content": "Translation of vesicular stomatitis messenger RNA by extracts from mammalian and plant cells. RNA was isolated from polyribosomes of vesicular stomatitis virus (VSV)-infected cells and tested for its ability to direct protein synthesis in extracts of animal and plant cells. In cell-free, non-preincubated extracts of rabbit reticulocytes, the 28S VSV RNA stimulated synthesis of a protein the size of the vesicular stomatitis virus L protein whereas the 13 to 15S RNA directed synthesis of the VSV M, N, NS, and possibly G proteins. In wheat germ extracts, 13 to 15S RNA also directed synthesis of the N, NS, M, and possibly G proteins. Analysis of extracts labeled with formyl [(35)S]methionine showed that the 28S RNA directed the initiation of synthesis of one protein, whereas the 13 to 15S RNA directed initiation of at least four proteins. It is concluded that the 28S RNA encodes only the L protein, whereas the 13 to 15S RNA is a mixture of species, presumably monocistronic, which code for the four other known vesicular stomatitis virus proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359431"}
{"pmid": "4359433", "title": "Physiopathology of portal hypertension. Circulatory neophysiology after portacaval shunt.", "content": "Physiopathology of portal hypertension. Circulatory neophysiology after portacaval shunt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359433"}
{"pmid": "4359432", "title": "Regulation of expression of late genes of bacteriophage T5.", "content": "Regulation of expression of late genes of bacteriophage T5. Amber mutants of bacteriophage T5 defective in gene C2 have been characterized. The product of this gene is required for the normal turn-on of synthesis of late RNA's and proteins, and, apparently, for the normal continued synthesis of early RNA's and proteins during late stages of infection. The inability of nonpermissive cells to synthesize any proteins, either late or early, during the late period after infection with a C2-mutant is not due to premature lysis of the infected cells, to a depletion of the cellular energy supply, or to degradation of phage DNA at late times. A possible role for the product of gene C2 in early and late transcription of the viral genome is suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359432"}
{"pmid": "4359435", "title": "Biochemical studies on the regulation of myocardial contractility.", "content": "Biochemical studies on the regulation of myocardial contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359435"}
{"pmid": "4359437", "title": "Periodic acid-Schiff positive myeloblasts in chronic myelogenous leukaemia: relation to karyotype evolution.", "content": "Periodic acid-Schiff positive myeloblasts in chronic myelogenous leukaemia: relation to karyotype evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359437"}
{"pmid": "4359434", "title": "Platelet function in hyperlipoproteinemia.", "content": "Platelet function in hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359434"}
{"pmid": "4359438", "title": "Pathology of gout.", "content": "Pathology of gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359438"}
{"pmid": "4359439", "title": "Pseudogout.", "content": "Pseudogout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359439"}
{"pmid": "4359449", "title": "Determinants for the establishment of permanent tissue culture lines from human gliomas.", "content": "Determinants for the establishment of permanent tissue culture lines from human gliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359449"}
{"pmid": "4359450", "title": "Comparative study of proteins, non-specific esterases and acid phosphatases in testicular fluids of different vertebrate species.", "content": "Comparative study of proteins, non-specific esterases and acid phosphatases in testicular fluids of different vertebrate species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359450"}
{"pmid": "4359454", "title": "Hemangiopericytoma.", "content": "Hemangiopericytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359454"}
{"pmid": "4359455", "title": "Spontaneous rupture of hepatoma: a misdiagnosed surgical emergency.", "content": "Spontaneous rupture of hepatoma: a misdiagnosed surgical emergency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359455"}
{"pmid": "4359458", "title": "Comparative studies of synaptic membrane protein solubilization by chlorpromazine and sodium dodecylsulfate.", "content": "Comparative studies of synaptic membrane protein solubilization by chlorpromazine and sodium dodecylsulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359458"}
{"pmid": "4359456", "title": "The control of renal cortical perfusion by the renin angiotensin system.", "content": "The control of renal cortical perfusion by the renin angiotensin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359456"}
{"pmid": "4359460", "title": "The effect of gold salts on the purine:pyrophosphate phosphoribosyltransferase enzymes of human blood cells.", "content": "The effect of gold salts on the purine:pyrophosphate phosphoribosyltransferase enzymes of human blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359460"}
{"pmid": "4359459", "title": "The effect of gold salts on the biosynthesis of uridine nucleotides in human granulocytes.", "content": "The effect of gold salts on the biosynthesis of uridine nucleotides in human granulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359459"}
{"pmid": "4359461", "title": "Effect of bioamines on the cellular differentiation of Hartmannella culbertsoni.", "content": "Effect of bioamines on the cellular differentiation of Hartmannella culbertsoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359461"}
{"pmid": "4359462", "title": "Levels of nucleoside and nucleotide kinases in rhesus monkey tissues.", "content": "Levels of nucleoside and nucleotide kinases in rhesus monkey tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359462"}
{"pmid": "4359463", "title": "Aspartate transcarbamylase from Streptococcus faecalis. Steady-state kinetic analysis.", "content": "Aspartate transcarbamylase from Streptococcus faecalis. Steady-state kinetic analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359463"}
{"pmid": "4359464", "title": "Allosteric and nonallosteric interactions with reduced nicotinamide adenine dinucleotide in two forms of cytoplasmic malic dehydrogenase.", "content": "Allosteric and nonallosteric interactions with reduced nicotinamide adenine dinucleotide in two forms of cytoplasmic malic dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359464"}
{"pmid": "4359467", "title": "Nasopharyngeal carcinoma (NPC). VI. Presence of an EBV nuclear antigen in fresh tumour biopsies. Preliminary results.", "content": "Nasopharyngeal carcinoma (NPC). VI. Presence of an EBV nuclear antigen in fresh tumour biopsies. Preliminary results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359467"}
{"pmid": "4359466", "title": "Parsley plastocyanin. The possible presence of sulfhydryl and tyrosine in the copper environment.", "content": "Parsley plastocyanin. The possible presence of sulfhydryl and tyrosine in the copper environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359466"}
{"pmid": "4359468", "title": "Arterial hypertension in retrospect.", "content": "Arterial hypertension in retrospect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359468"}
{"pmid": "4359465", "title": "Identification of a distinction between cytoplasmic histone synthesis and subsequent histone deposition within the nucleus.", "content": "Identification of a distinction between cytoplasmic histone synthesis and subsequent histone deposition within the nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359465"}
{"pmid": "4359470", "title": "Poly(adenosine diphosphoribose) polymerase in mammalian nuclei. Characterization of the activity in mouse fibroblasts (LS cells).", "content": "Poly(adenosine diphosphoribose) polymerase in mammalian nuclei. Characterization of the activity in mouse fibroblasts (LS cells).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359470"}
{"pmid": "4359471", "title": "Properties of arginine kinase from Drosophila melanogaster.", "content": "Properties of arginine kinase from Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359471"}
{"pmid": "4359472", "title": "Immunochemical studies on rat-liver microsomal NAD glycohydrolase.", "content": "Immunochemical studies on rat-liver microsomal NAD glycohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359472"}
{"pmid": "4359473", "title": "Fine structure of epithelial cell of secretory endometrium in unexplained primary infertility.", "content": "Fine structure of epithelial cell of secretory endometrium in unexplained primary infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359473"}
{"pmid": "4359474", "title": "Sperm transport through vas deferens: review of hypotheses and suggestions for a quantitative model.", "content": "Sperm transport through vas deferens: review of hypotheses and suggestions for a quantitative model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359474"}
{"pmid": "4359475", "title": "Interaction of bilayers with basic polypeptides. II. Interaction of phospholipid bilayers with copolymer L-lysine-L-phenylalanine.", "content": "Interaction of bilayers with basic polypeptides. II. Interaction of phospholipid bilayers with copolymer L-lysine-L-phenylalanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359475"}
{"pmid": "4359476", "title": "Studies on plasma membranes. XX. Sialidase in hepatic plasma membranes.", "content": "Studies on plasma membranes. XX. Sialidase in hepatic plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359476"}
{"pmid": "4359477", "title": "Hierarchy levels in the control of blood flow to the hind limb of the dog. A new approach to the analysis of integrative neural cardiovascular control.", "content": "Hierarchy levels in the control of blood flow to the hind limb of the dog. A new approach to the analysis of integrative neural cardiovascular control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359477"}
{"pmid": "4359478", "title": "Event train decoders with many inputs, pulse density versus momentaneous frequency.", "content": "Event train decoders with many inputs, pulse density versus momentaneous frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359478"}
{"pmid": "4359479", "title": "Considerations on models of movement detection.", "content": "Considerations on models of movement detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359479"}
{"pmid": "4359480", "title": "Equine infectious anemia.", "content": "Equine infectious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359480"}
{"pmid": "4359482", "title": "Breathing before birth in animals and man. An essay in developmental medicine.", "content": "Breathing before birth in animals and man. An essay in developmental medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359482"}
{"pmid": "4359481", "title": "Drug therapy. Antacid therapy.", "content": "Drug therapy. Antacid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359481"}
{"pmid": "4359469", "title": "Choline acetyltransferase level in cyclic AMP and x-ray induced morphologically differentiated neuroblastoma cells in culture.", "content": "Choline acetyltransferase level in cyclic AMP and x-ray induced morphologically differentiated neuroblastoma cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359469"}
{"pmid": "4359484", "title": "The central effects of thiopental and morphine in rats with renal hypertension.", "content": "The central effects of thiopental and morphine in rats with renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359484"}
{"pmid": "4359485", "title": "Characterization of a feedback-resistant phosphoribosylpyrophosphate synthetase from cultured, mutagenized hepatoma cells that overproduce purines.", "content": "Characterization of a feedback-resistant phosphoribosylpyrophosphate synthetase from cultured, mutagenized hepatoma cells that overproduce purines. A clone of cells in which the regulation of purine metabolism is genetically altered was selected and isolated from chemically mutagenized HTC cells (a line of rat hepatoma cells in continuous culture). The clone, designated MAU V, was selected for increased ability to salvage exogenous purines by isolating it in medium containing methylmercaptopurine ribonucleoside, adenine, and uridine, in which medium wild-type cells cannot divide. We have characterized these cells as having an increased rate of de novo purine biosynthesis, apparently as the result of an altered phosphoribosylpyrophosphate (PRPP) synthetase. The altered enzyme has normal catalytic properties but an altered sensitivity to feedback inhibition by purine and pyrimidine nucleotides. The types of inhibitions (competitive and uncompetitive) exerted by AMP, ADP, and TDP on the wild-type enzyme have been maintained in the altered enzyme, but values for K(i) have been increased by factors of 10, 17.5, and 5, respectively. The specific catalytic activities of AMP: pyrophosphate phosphoribosyltransferase and IMP:pyrophosphate phosphoribosyltransferase are normal. The mutant cell may serve as a model for a specific human disease, one type of dominantly inherited overproduction hyperuricemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359485"}
{"pmid": "4359486", "title": "Studies on the orientation of cyclic AMP-dependent protein kinase in human erythrocyte membranes.", "content": "Studies on the orientation of cyclic AMP-dependent protein kinase in human erythrocyte membranes. The topographic location of cyclic AMP-dependent protein kinase has been studied in preparations of permeable and sealed membranes derived from human erythrocytes. Both the catalytic and cyclic AMP-binding components of protein kinase are localized on the inner, cytoplasmic, surface of the plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359486"}
{"pmid": "4359487", "title": "Temperature-dependent formation of dimers and oligomers of mitochondrial DNA in cells transformed by a thermosensitive mutant of Rous sarcoma virus.", "content": "Temperature-dependent formation of dimers and oligomers of mitochondrial DNA in cells transformed by a thermosensitive mutant of Rous sarcoma virus. In chick-embryo fibroblasts infected by T5, a temperature-sensitive mutant of Schmidt-Ruppin Rous sarcoma virus, the level of catenated dimeric and oligomeric mitochondrial DNA is temperature-dependent and correlates with the phenotypic manifestation of transformation. At the permissive temperature (36 degrees ), where transformation is expressed, the 2- to 3-fold elevated level characteristic of cells transformed by the wild-type Rous sarcoma virus was observed, but at the nonpermissive temperature (41 degrees ), at which cells appear normal and behave normally, the oligomer level was characteristic of uninfected cells. Temperature shifts from 41 to 36 degrees and vice versa resulted in phenotypic reversion and reversals of the respective levels of multiple-length DNA. Cellular growth rates were not altered. Treatment of control cells with cycloheximide resulted in a 5-fold increase of oligomeric DNA, whereas exposure to 9-beta-D-arabinofuranosyladenine had little effect. With both inhibitors, nuclear but not mitochondrial DNA synthesis was inhibited. The possible relation of formation of oligomeric mitochondrial DNA to alterations in the mitochondrial membranes of transformed cells and to inhibition of protein synthesis in the cytoplasm is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359487"}
{"pmid": "4359488", "title": "Size and base composition of RNA in supercoiled plasmid DNA.", "content": "Size and base composition of RNA in supercoiled plasmid DNA. The average size and base composition of the covalently integrated RNA segment in supercoiled ColE(1) DNA synthesized in Escherichia coli in the presence of chloramphenicol (CM-ColE(1) DNA) have been determined by two independent methods. The two approaches yielded similar results, indicating that the RNA segment in CM-ColE(1) DNA contains GMP at the 5' end and comprises on the average 25 to 26 ribonucleotides with a base composition of 10-11 G, 3 A, 5-6 C, and 6-7 U.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359488"}
{"pmid": "4359490", "title": "Interrelationship between adenylate cyclase activity, adenosine 3':5' cyclic monophosphate phosphodiesterase activity, adenosine 3':5' cyclic monophosphate levels, and growth of cells in culture.", "content": "Interrelationship between adenylate cyclase activity, adenosine 3':5' cyclic monophosphate phosphodiesterase activity, adenosine 3':5' cyclic monophosphate levels, and growth of cells in culture. To investigate how cell population density influences the intracellular concentration of cyclic AMP we have measured adenylate cyclase and cyclic AMP phosphodiesterase activities and cyclic AMP levels at various stages of cell density in normal rat-kidney (NRK) cells, which exhibit contact-inhibition of growth, and in normal chick-embryo fibroblasts (CEF), which do not show contact inhibition of growth under our conditions. Until NRK cells reach confluency, both activities increase with increasing cell population and cyclic AMP levels are low. As NRK cells reach confluency, cyclic AMP phosphodiesterase activity decreases somewhat whereas adenylate cyclase activity continues to rise. This increase in synthetic ability is accompanied by the increase in cyclic AMP levels which occurs in these cells at confluency. In CEF grown in 5% serum where density-dependent inhibition of growth is not observed, both adenylate cyclase and cyclic AMP phosphodiesterase activities increase proportionately with increasing cell population density. No significant alteration occurs in the ratio between these two enzyme activities and no change is observed in cyclic AMP levels. The NaF-stimulated activity in NRK cells increases with increasing cell density until the cells reach confluency; thereafter the NaF-stimulated activity remains constant. In contrast, the NaF-stimulated activity observed in CEF does not vary appreciably between light and heavy density. The observed changes in the enzymes of cyclic AMP metabolism accurately reflect the changes in cyclic AMP concentration as a function of cell population density. The data indicate that these two enzyme activities respond to increasing cell density to elicit a rise in intracellular cyclic AMP levels. The elevated cyclic AMP levels are thought to be involved in the regulation of cellular growth rate and the mediation of contact inhibition of growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359490"}
{"pmid": "4359491", "title": "Regulation of cyclic nucleotide concentrations in photoreceptors: an ATP-dependent stimulation of cyclic nucleotide phosphodiesterase by light.", "content": "Regulation of cyclic nucleotide concentrations in photoreceptors: an ATP-dependent stimulation of cyclic nucleotide phosphodiesterase by light. Regulation of cyclic nucleotide concentrations in rod outer segments (Rana pipiens) has been further examined. The present studies show that illumination markedly diminishes the concentration of cyclic nucleotides in suspensions of photoreceptor membranes, but the locus of regulation is cyclic nucleotide phosphodiesterase (EC 3.1.4.c) (light-stimulated) and not adenylate cyclase. There is a marked disproportionality between bleaching of rhodopsin and stimulation of phosphodiesterase. Bleaching only 0.6% of the rhodopsin produces half the stimulation produced by bleaching 100% of the rhodopsin. The process of activation of phosphodiesterase by light is in two steps, a light-dependent step followed by an ATP-dependent step. Illumination (in the absence of ATP) produces a trypsin-resistant, heat-labile, macromolecular stimulator. In the presence of 0.75 mM ATP (GTP or ITP) this stimulator produces a greater than 5-fold increases in the V(max) of photoreceptor phosphodiesterase without changing the K(m). At physiological substrate concentrations (10(-7) M) the rate of hydrolysis of cyclic GMP is 23 times greater than that of cyclic AMP. The light-produced stimulator appears unique to the photoreceptor membranes and does not activate phosphodiesterase in other tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359491"}
{"pmid": "4359489", "title": "Phosphorylation of 5-bromodeoxycytidine in cells infected with herpes simplex virus.", "content": "Phosphorylation of 5-bromodeoxycytidine in cells infected with herpes simplex virus. 5-Bromodeoxycytidine is phosphorylated to 5-bromodeoxycytidine 5'-monophosphate in extracts of cells infected with herpes simplex virus but not in extracts of uninfected cells. The conversion of 5-bromodeoxycytidine to nucleotides and its utilization for DNA synthesis in uninfected cells occurs by deamination of 5-bromodeoxycytidine to 5-bromodeoxyuridine followed by phosphorylation of 5-bromodeoxyuridine to 5-bromodeoxyuridine 5'-monophosphate. In contrast, in cells infected with herpes simplex virus, 5-bromodeoxycytidine is phosphorylated directly to 5-bromodeoxycytidine 5'-monophosphate, which can then be deaminated to 5-bromodeoxyuridine 5'-monophosphate and incorporated into DNA. These results indicate a difference in the substrate specificity of nucleoside kinases induced by herpes simplex virus and the enzymes present in uninfected cells. It is suggested that this difference in substrate specificity between virus-induced and host-cell enzymes may allow selective chemotherapy of herpes simplex infections with 5-bromo- or 5-iododeoxycytidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359489"}
{"pmid": "4359492", "title": "Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung slices.", "content": "Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung slices. Bradykinin, 1-100 mug/ml, produced a rapid rise in the concentration of 3':5'-guanosine monophosphate (cyclic GMP) and 3':5'-adenosine monophosphate (cyclic AMP) in slices of guinea pig lung. Concentrations of both nucleotides reached a maximum in about 2 min, then declined to a basal levels in 6-12 min. The transient nature of the effect was presumbaly due to the rapid destruction of bradykinin as evidenced by (1) reaccumulation of nucleotides when bradykinin was added a second time, and (2) potentiation of the bradykinin effects by pyroGlu-Lys-Trp-Ala-Pro, a peptide that inhibits inactivation of bradykinin by kininase. It has been reported elsewhere that histamine, prostaglandins E(1) and E(2), and beta-adrenergic stimulation can cause accumulation of cyclic AMP in lung slices without affecting cyclic GMP concentration, whereas acetylcholine increases the concentrations of both cyclic GMP and cyclic AMP. Thus it was possible that the effects of bradykinin were indirect, i.e., secondary to release of one or more of these compounds. Promethazine (an antihistamine), propranolol (a beta-adrenergic blocking agent) and atropine (an anticholinergic agent) did not alter basal cyclic nucleotide concentrations or the effects of bradykinin. Two inhibitors of prostaglandin synthesis, indomethacin and aspirin, which alone were without effect, in the presence of bradykinin completely prevented the rise in cyclic AMP but did not interfere with cyclic GMP accumulation. Similarly, the effect of acetylcholine on cyclic AMP was abolished by indomethacin while that on cyclic GMP was unaltered. We suggest that in lung and probably in other tissues, bradykinin, acetylcholine, and perhaps other stimuli enhance the synthesis and release of prostaglandins as one of the consequences of their effects on cyclic GMP metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359492"}
{"pmid": "4359494", "title": "The importance of calcium ions for the regulation of guanosine 3':5'-cyclic monophosphage levels.", "content": "The importance of calcium ions for the regulation of guanosine 3':5'-cyclic monophosphage levels. Guanosine 3':5'-cyclic monosphosphate (cyclic GMP) levels in the ductus deferens of the rat were increased 2- to 3-fold by acetylcholine (10-1000 muM) or by 125 mM KCl, while adenosine 3':5'-cyclic monophosphate (cyclic AMP) levels were not changed. After incubation for 30 min in the absence of Ca(++), cyclic GMP control levels were decreased by 85% and were not affected by acetylcholine or KCl. The readdition of Ca(++) (1.8 mM) for 3 min to Ca(++)-deprived tissue partially restored basal cyclic GMP levels and the effects of acetylcholine and KCl. The addition of Sr(++) (3.6 mM) or of Ba(++) (1.8 or 10 mM) also caused an increase in basal cyclic GMP in Ca(++)-deprived tissue. Cyclic AMP levels were not significantly changed under any of these conditions. The addition of the phosphodiesterase inhibitor, 1-methyl-3-isobutylxanthine (0.1 mM), to ductus deferentes increased the amount of cyclic AMP about 50% and that of cyclic GMP about 2-fold. The later effect also depended on the presence of Ca(++). 1-Methyl-3-isobutylxanthine (0.1 mM) increased cyclic GMP and cyclic AMP levels in slices of rat submaxillary glands. Methacholine increased cyclic GMP if added in the presence of methyl isobutylxanthine. Cyclic GMP control levels and the effect of methyl isobutylxanthine were unchanged by Ca(++) omission, but the effect of methacholine was abolished.These findings indicate that calcium ions are important for the control of cyclic GMP levels in these tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359494"}
{"pmid": "4359493", "title": "Properties of the beta nerve growth factor receptor of avian dorsal root ganglia.", "content": "Properties of the beta nerve growth factor receptor of avian dorsal root ganglia. Iodination of the beta nerve growth factor protein up to 4.1 iodines per mole of nerve growth factor was achieved with no loss of biological activity. At this level of incorporation no native or monoiodo nerve growth factor remained, the major species being the tri- and tetraiodo derivatives. An (125)I-labeled beta nerve growth factor of high specific activity containing 0.5 iodine per mole of beta nerve growth factor was used to determine the specific binding of nerve growth factor to dorsal root ganglion cells of 8-day-old embryonic chicks. The specific binding of (125)I-labeled nerve growth factor reached saturation at 30-50 ng/ml and half-saturation at 7-8 ng/ml (0.26 nM). The number of receptors per responsive medio-dorsal cell was calculated to be about 2 x 10(4). The pattern of displacement of bound (125)I-labeled beta nerve growth factor by native beta nerve growth factor showed that the two proteins had identical affinities for the receptor. The specificity of the binding for beta nerve growth factor was demonstrated by the fact that only native beta nerve growth factor displaced the bound (125)I-labeled form. Partially inactivated derivatives of beta nerve growth factor retained the same fraction of their specific-binding capacity as of their biological activity. The specificity of the binding for cell type was shown by the lack of any specific component of (125)I-labeled beta nerve growth factor binding to liver or brain cells. The rate constant for association of beta nerve growth factor with its receptor, k(1), was 1.0 x 10(7) mol(-1) sec(-1) and the rate constant for dissociation, k(-1), 1.2 x 10(-8) sec(-1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359493"}
{"pmid": "4359502", "title": "Ultrastructure of herpes simplex virus infection of the nervous system of mice.", "content": "Ultrastructure of herpes simplex virus infection of the nervous system of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359502"}
{"pmid": "4359504", "title": "Recurrent control from motor axon collaterals of Ia inhibitory pathways to ventral spinocerebellar tract neurones.", "content": "Recurrent control from motor axon collaterals of Ia inhibitory pathways to ventral spinocerebellar tract neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359504"}
{"pmid": "4359503", "title": "Nerve biopsy findings in two cases of Tangier disease.", "content": "Nerve biopsy findings in two cases of Tangier disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359503"}
{"pmid": "4359505", "title": "Parallelism between mechanical and metabolic responses to cholecystokinin and prostaglandin E2 in extrahepatic biliary tract.", "content": "Parallelism between mechanical and metabolic responses to cholecystokinin and prostaglandin E2 in extrahepatic biliary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359505"}
{"pmid": "4359507", "title": "An introductory note to ginseng.", "content": "An introductory note to ginseng.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359507"}
{"pmid": "4359506", "title": "Experimental and clinical oncology in People's Republic of China.", "content": "Experimental and clinical oncology in People's Republic of China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359506"}
{"pmid": "4359509", "title": "Endocrine dysfunction and anencephaly and spina bifida: an epidemiologic hypothesis.", "content": "Endocrine dysfunction and anencephaly and spina bifida: an epidemiologic hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359509"}
{"pmid": "4359508", "title": "Anticancer Chinese herbal medicines.", "content": "Anticancer Chinese herbal medicines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359508"}
{"pmid": "4359511", "title": "Effect of angiotensin II and its nonpressor derivatives on renin secretion.", "content": "Effect of angiotensin II and its nonpressor derivatives on renin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359511"}
{"pmid": "4359510", "title": "Rhinovirus infections in an industrial population. V. Change in distribution of serotypes.", "content": "Rhinovirus infections in an industrial population. V. Change in distribution of serotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359510"}
{"pmid": "4359512", "title": "Effect of prostaglandins on renin reactivity.", "content": "Effect of prostaglandins on renin reactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359512"}
{"pmid": "4359513", "title": "Angiotensin interaction with thirst mechanisms.", "content": "Angiotensin interaction with thirst mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359513"}
{"pmid": "4359515", "title": "Reticuloendotheliosis in a duck.", "content": "Reticuloendotheliosis in a duck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359515"}
{"pmid": "4359514", "title": "Sympathetic cardiac stimulation in Bufo marinus under MS-222 anesthesia.", "content": "Sympathetic cardiac stimulation in Bufo marinus under MS-222 anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359514"}
{"pmid": "4359517", "title": "Mechanism of action of a microsomal inhibitor of protein synthesis potentiated by oxidized glutathione.", "content": "Mechanism of action of a microsomal inhibitor of protein synthesis potentiated by oxidized glutathione. Extracts of microsomal fractions cause an inhibition of protein synthesis that is most pronounced in the presence of 0.1mm-GSSG and 0.01mm-GTP, and is abolished by thiol or 0.4mm-GTP (Scornik et al., 1967). Fractionation of microsomal extracts showed that this inhibition of protein synthesis was caused by an enzyme, nucleoside diphosphate phosphohydrolase. Direct inhibition of protein synthesis on detergent-treated polyribosomes by 0.1mm-GSSG was observed under conditions of GTP limitation induced by omission of a GTP-regenerating system, or addition of a nucleoside triphosphate diphosphohydrolase. Thus GSSG potentiated the inhibition of protein synthesis caused by an enzyme that promoted removal of GTP. The inhibition was abolished by adding 4mm-2-mercaptoethanol or 0.4mm-GTP. Nucleoside diphosphate phosphohydrolase was thought also to act by promoting removal of GTP, thus causing an inhibition of protein synthesis that was potentiated by GSSG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359517"}
{"pmid": "4359519", "title": "Cross sensitivity to mono- and bifunctional alkylating agents of three radiation-sensitive Saccharomyces mutants.", "content": "Cross sensitivity to mono- and bifunctional alkylating agents of three radiation-sensitive Saccharomyces mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359519"}
{"pmid": "4359518", "title": "The effects of cytoplasmic extracts on DNA synthesis in vitro.", "content": "The effects of cytoplasmic extracts on DNA synthesis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359518"}
{"pmid": "4359520", "title": "Effects of storage conditons on survival and free radical populations in dried irradiated spores of Osmunda regalis.", "content": "Effects of storage conditons on survival and free radical populations in dried irradiated spores of Osmunda regalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359520"}
{"pmid": "4359516", "title": "Activation of volatile fatty acids in bovine liver and rumen epithelium. Evidence for control by autoregulation.", "content": "Activation of volatile fatty acids in bovine liver and rumen epithelium. Evidence for control by autoregulation. 1. The total capacities of homogenates of bovine liver and rumen epithelium to activate acetate, propionate and butyrate were determined. 2. Activating capacities were assayed by measuring the rate of formation of the corresponding CoA esters. The methods used for determining the concentrations of the CoA esters allowed the CoA esters of acetate, propionate and butyrate to be distinguished. It was thus possible to investigate the effect of the presence of a second volatile fatty acid on the rate at which a given volatile fatty acid was activated. 3. The propionate-activating capacity in rumen epithelium was decreased by about 87% in the presence of butyrate, the acetate-activating capacity in liver was decreased by about 55% in the presence of either propionate or butyrate, and the butyrate-activating capacity in liver was decreased by about 40-50% in the presence of propionate. 4. All three activating capacities in liver appeared to be located in the mitochondrial matrix and membrane. The three activating capacities had similar locations to each other in rumen epithelium as well, although in this case activity was more evenly divided between the mitochondria and the cytoplasm. 5. The relative activating capacities towards the volatile fatty acids in the two tissues, together with the ability of one volatile fatty acid to inhibit the activation of another volatile fatty acid, appear to ensure that butyrate is mainly metabolized in the rumen epithelium and that propionate is metabolized in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359516"}
{"pmid": "4359524", "title": "The metabolism of biological alkylating agents.", "content": "The metabolism of biological alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359524"}
{"pmid": "4359531", "title": "Isolation of temperature sensitive mammalian cells by selective detachment.", "content": "Isolation of temperature sensitive mammalian cells by selective detachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359531"}
{"pmid": "4359532", "title": "A temperature-sensitive function in a Chinese hamster line affecting DNA synthesis.", "content": "A temperature-sensitive function in a Chinese hamster line affecting DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359532"}
{"pmid": "4359522", "title": "Newer knowledge of chemotherapy in the treatment of tuberculosis of bones and joints.", "content": "Newer knowledge of chemotherapy in the treatment of tuberculosis of bones and joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359522"}
{"pmid": "4359533", "title": "The importance of the techniques employed during the enzymatic preparation of isolated liver parenchymal cells.", "content": "The importance of the techniques employed during the enzymatic preparation of isolated liver parenchymal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359533"}
{"pmid": "4359534", "title": "Changes in membrane transport function in G0 and G1 cells.", "content": "Changes in membrane transport function in G0 and G1 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359534"}
{"pmid": "4359537", "title": "Origin of esterified cholesterol transported in the very low density lipoproteins of human plasma.", "content": "Origin of esterified cholesterol transported in the very low density lipoproteins of human plasma. In two subjects the specific activity of esterified cholesterol in plasma lipoprotein subfractions was measured for up to 9 hr after an intravenous injection of [(3)H]mevalonic acid. It was found to be consistently higher in larger (S(f) > 100) than in smaller (S(f) 20-100) very low density lipoproteins (VLDL). Four subjects were given an intravenous injection of heparin so that the VLDL could be studied as its concentration fell and subsequently rose again. During the first hour the relative reduction was greatest for triglyceride, intermediate for free cholesterol, and least for esterified cholesterol. Between 1 and 7 hr postheparin, the VLDL pool was restored, but the pattern of increase of individual lipids was not parallel. The triglyceride increment was much greater during the 1-4-hr period than during the 4-7-hr period; in three of the subjects the free cholesterol increment was also greater during the earlier period. The increase in esterified cholesterol, however, was consistently greater during the 4-7-hr period. In six other subjects the specific activity of VLDL esterified cholesterol was related to that of its possible plasma precursors in samples collected at 1-hr intervals for 8 hr after the injection of [(3)H]mevalonic acid. Free cholesterol emerged as the most likely immediate precursor with the possibility of a hepatic as well as an intraplasma origin. The results did not support a major in vivo transfer of esterified cholesterol from high density lipoproteins to VLDL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359537"}
{"pmid": "4359535", "title": "Deoxyglucose transport of uninfected, murine sarcoma virus-transformed, and murine leukemia virus-infected mouse cells.", "content": "Deoxyglucose transport of uninfected, murine sarcoma virus-transformed, and murine leukemia virus-infected mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359535"}
{"pmid": "4359521", "title": "Application of electron spin resonance in research on mineralized tissues.", "content": "Application of electron spin resonance in research on mineralized tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359521"}
{"pmid": "4359538", "title": "Metabolism of sulfoquinovosyl diglyceride in Chlorella pyrenoidosa by sulfoquinovosyl monoglyceride: fatty acyl CoA acyltransferase and sulfoquinovosyl glyceride: fatty acyl ester hydrolase pathways.", "content": "Metabolism of sulfoquinovosyl diglyceride in Chlorella pyrenoidosa by sulfoquinovosyl monoglyceride: fatty acyl CoA acyltransferase and sulfoquinovosyl glyceride: fatty acyl ester hydrolase pathways. Cell-free preparations of Chlorella pyrenoidosa catalyze the transfer of the fatty acyl moiety of fatty acyl CoA derivatives to sulfoquinovosyl monoglyceride to form sulfoquinovosyl diglyceride. This reaction is stimulated by Triton X-100 concentrations of up to 0.6 mg/ml and has a pH optimum of 7.7. Similar Chlorella preparations catalyze the stepwise removal of both fatty acyl groups from sulfoquinovosyl diglyceride to form sulfoquinovosyl monoglyceride and then sulfoquinovosyl glycerol. This reaction is inhibited by both calcium and magnesium. The nonionic surfactant Triton X-100 inhibits the enzymatic deacylation at concentrations of less than 0.5 mg/ml but stimulates it at higher concentrations. The pH optimum for the deacylation of sulfoquinovosyl glycerides is 8.2, with little activity observed below pH 8. The enzymatic activities for both the transacylation and deacylation reactions are associated with a 30,000 g particulate fraction of Chlorella. Sulfoquinovosyl glycerol was found not to be an acceptor of the fatty acyl moiety of fatty acyl CoA derivatives. Methods are described for the preparation of sulfoquinovosyl monoglyceride, sulfoquinovose, and 3-sulfo-1,2-propanediol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359538"}
{"pmid": "4359539", "title": "Studies of glucagon resistance in large rat adipocytes: 125I-labeled glucagon binding and lipolytic capacity.", "content": "Studies of glucagon resistance in large rat adipocytes: 125I-labeled glucagon binding and lipolytic capacity. This study is concerned with potential modifications of large fat cells from adult rats (400-450 g) that make them resistant to stimulation by glucagon. The lipolytic capacity and (125)I-labeled glucagon-binding capability of these cells were compared with these properties of small glucagon-sensitive cells from young rats (130-160 g). As determined by maximal stimulation with theophylline, dibutyryl cAMP, or epinephrine, the lipolytic capacity of large cells was not markedly different from small cells, which suggests that an alteration contributing to glucagon insensitivity is not present in the enzymes involved with hormone-mediated lipolysis. Glucagon-binding studies did indicate a difference between the two cell types. Both large cells and particulate fractions from large cells bound less (125)I-labeled glucagon than small cells or small-cell particles. That diminished binding is not a consequence of glucagon degradation is indicated by the similar amounts of (125)I-labeled glucagon degraded by both cell types. The decrease in (125)I-labeled glucagon binding was not as marked as the decrease in lipolytic response to glucagon stimulation. This lack of correlation and the relationship between elevated phosphodiesterase levels and glucagon insensitivity described in the accompanying report suggest that diminished binding explains only in part the marked resistance to glucagon found in large cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359539"}
{"pmid": "4359540", "title": "Role of phosphodiesterase in glucagon resistance of large adipocytes.", "content": "Role of phosphodiesterase in glucagon resistance of large adipocytes. The role of phosphodiesterase in glucagon resistance of large adipocytes was investigated. A comparison was made of phosphodiesterase activities of homogenates prepared from isolated small (mean diameter approximately 45 micro m) and large (mean diameter approximately 78 micro m) adipocytes, using various concentrations (5 x 10(-4) to 1 x 10(-7) M) of 3',5'-cAMP. Kinetic analyses revealed two distinct catalytic activities (high and low affinities) in both cell types; however, the activities of both high- and low-affinity enzymes were significantly elevated in large adipocytes. Lipolysis was measured in isolated adipocytes in the presence of different concentrations (0.1-0.6 mM) of the phosphodiesterase inhibitor aminophylline. Large adipocytes were less responsive to low levels of methylxanthine, suggesting that greater amounts of phosphodiesterase must be inhibited before lipolysis can be stimulated. To evaluate the influence of phosphodiesterase during glucagon-stimulated lipolysis, small and large adipocytes were incubated with a maximally effective concentration of glucagon (1.5 x 10(-6) M) in combination with various concentrations (0.1-0.6 mM) of aminophylline. Although the glucagon effect was potentiated in both cell types, the maximum lipolytic response of large adipocytes (at 0.4 mM aminophylline) was approximately 36% lower than that observed in small adipocytes (at 0.2 mM aminophylline). This reduction correlates closely with the decreased glucagon binding present in large cells; therefore, it appears that the glucagon-resistant state is adequately explained by elevations in phosphodiesterase levels and diminished glucagon-cell association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359540"}
{"pmid": "4359541", "title": "Ultrastructural and physiological evidence for corticosteroid-induced alterations in hepatic production of very low density lipoprotein particles.", "content": "Ultrastructural and physiological evidence for corticosteroid-induced alterations in hepatic production of very low density lipoprotein particles. The cause of corticosteroid-induced hyperlipoproteinemia was studied in rats and mice. An ultrastructural morphometric method was utilized to demonstrate alterations in hepatocyte very low density lipoprotein content, and Triton WR 1339-treated rats were used to identify changes in the removal of very low density lipoproteins from plasma. The results show that corticosteroid treatment results in (1) an increase in both plasma triglyceride and cholesterol levels, (2) an increase in rate of accumulation of triglyceride after inhibition of very low density lipoprotein removal by Triton, and (3) an increase in the number and size of Golgi-associated very low density lipoprotein particles in hepatocytes. These combined results suggest that corticosteroids induce hyperlipoproteinemia through increased hepatic production of very low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359541"}
{"pmid": "4359523", "title": "Idiopathic arthropathy of the elbow.", "content": "Idiopathic arthropathy of the elbow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359523"}
{"pmid": "4359542", "title": "Changes of gangliosides and other lipids in skeletal muscle from rabbits with experimental dystrophy.", "content": "Changes of gangliosides and other lipids in skeletal muscle from rabbits with experimental dystrophy. Comparison of the skeletal muscles from vitamin E-deficient and control rabbits showed that the muscles from the deficient animals had lower contents of protein and glycogen but more water and lipid. Increases of individual lipids per unit weight of muscle from deficient animals compared with those from control animals were 2.2-fold for gangliosides, 2.18-fold for cholesterol, 1.74-fold for sulfatides, and 1.45-fold for neutral glycosylceramides. Total phospholipids did not change; this was the result of an increase in sphingomyelin (1.47-fold) and a decrease of phosphatidylcholine to 83% of the control, while the other fractions remained unchanged. When the measurements were referred to total muscle, the contents of cholesterol, gangliosides, sulfatides, neutral glycosylceramides, and sphingomyelin in muscle from vitamin E-deficient rabbits were also above those of the control rabbits, and only the phosphatidylcholine content was decreased. It was not possible to determine whether the alteration of lipid content preceded or followed the onset of signs of muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359542"}
{"pmid": "4359543", "title": "Synthesis and biological activity of 9-beta-D-arabinofuranosyladenine cyclic 3',5'-phosphate and 9-beta-D-arabinofuranosylguanine cyclic 3',5'-phosphate.", "content": "Synthesis and biological activity of 9-beta-D-arabinofuranosyladenine cyclic 3',5'-phosphate and 9-beta-D-arabinofuranosylguanine cyclic 3',5'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359543"}
{"pmid": "4359545", "title": "Angiotensin II analogs. 11. Further studies on des-aspartyl-angiotensin II.", "content": "Angiotensin II analogs. 11. Further studies on des-aspartyl-angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359545"}
{"pmid": "4359546", "title": "Antiviral agents. 1-Aralkyloxyadenosines.", "content": "Antiviral agents. 1-Aralkyloxyadenosines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359546"}
{"pmid": "4359544", "title": "13-Alkylpyrimidine nucleosides. Preparation and properties of 5-ethyl-2'-deoxycytidine and related nucleosides.", "content": "13-Alkylpyrimidine nucleosides. Preparation and properties of 5-ethyl-2'-deoxycytidine and related nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359544"}
{"pmid": "4359547", "title": "Phospholipases. I. Effect of n-alkanols on the rate of enzymatic hydrolysis of egg phosphatidylcholine.", "content": "Phospholipases. I. Effect of n-alkanols on the rate of enzymatic hydrolysis of egg phosphatidylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359547"}
{"pmid": "4359548", "title": "Phospholipases. II. Enzymatic hydrolysis of lecithin: effects of structure, cholesterol content, and sonication.", "content": "Phospholipases. II. Enzymatic hydrolysis of lecithin: effects of structure, cholesterol content, and sonication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359548"}
{"pmid": "4359551", "title": "Antipseudomonal effect of polymyxin and phenylethanol.", "content": "Antipseudomonal effect of polymyxin and phenylethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359551"}
{"pmid": "4359549", "title": "The anatomy of the parotoid gland in Bufonidae with some histochemical findings. I. Bufo marinus.", "content": "The anatomy of the parotoid gland in Bufonidae with some histochemical findings. I. Bufo marinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359549"}
{"pmid": "4359550", "title": "Carcinoma of the adrenal gland in children.", "content": "Carcinoma of the adrenal gland in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359550"}
{"pmid": "4359552", "title": "Evidence for the action of d-lysergic acid diethylamide, mescaline and bufotenine on 5-hydroxytryptamine receptors in umbilical vasculature.", "content": "Evidence for the action of d-lysergic acid diethylamide, mescaline and bufotenine on 5-hydroxytryptamine receptors in umbilical vasculature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359552"}
{"pmid": "4359554", "title": "The effects of dibutyryl cyclic adenosine 3',5'-monophosphate, theophylline and aminophylline on neuromuscular transmission in the rat.", "content": "The effects of dibutyryl cyclic adenosine 3',5'-monophosphate, theophylline and aminophylline on neuromuscular transmission in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359554"}
{"pmid": "4359553", "title": "The elimination of 5-hydroxyindoleacetic acid from cerebrospinal fluid: characteristics of the acid transport system of the choroid plexus.", "content": "The elimination of 5-hydroxyindoleacetic acid from cerebrospinal fluid: characteristics of the acid transport system of the choroid plexus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359553"}
{"pmid": "4359556", "title": "Clostridium perfringens exotoxins. II. Purification and some properties of theta-toxin.", "content": "Clostridium perfringens exotoxins. II. Purification and some properties of theta-toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359556"}
{"pmid": "4359557", "title": "Establishment of two inbred strains of the rat for cancer research in tissue culture.", "content": "Establishment of two inbred strains of the rat for cancer research in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359557"}
{"pmid": "4359555", "title": "Release of renal prostaglandin by catecholamines: relationship to renal endocrine function.", "content": "Release of renal prostaglandin by catecholamines: relationship to renal endocrine function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359555"}
{"pmid": "4359561", "title": "Salmonella typhimurium mutants affecting establishment of lysogeny.", "content": "Salmonella typhimurium mutants affecting establishment of lysogeny.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359561"}
{"pmid": "4359562", "title": "Interactions among genes controlling sensitivity to radiation and alkylation in yeast.", "content": "Interactions among genes controlling sensitivity to radiation and alkylation in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359562"}
{"pmid": "4359563", "title": "Pathobiology of nucleocytoplasmic exchange.", "content": "Pathobiology of nucleocytoplasmic exchange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359563"}
{"pmid": "4359564", "title": "Intercellular junctions in normal and in malignant cells.", "content": "Intercellular junctions in normal and in malignant cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359564"}
{"pmid": "4359566", "title": "Viral and immunologic studies of human neoplasms.", "content": "Viral and immunologic studies of human neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359566"}
{"pmid": "4359565", "title": "Cellular DNA replication in viral infection.", "content": "Cellular DNA replication in viral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359565"}
{"pmid": "4359590", "title": "Arterial infusion chemotherapy of hepatoma.", "content": "Arterial infusion chemotherapy of hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359590"}
{"pmid": "4359591", "title": "Thyroidography and thyrolymphography.", "content": "Thyroidography and thyrolymphography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359591"}
{"pmid": "4359593", "title": "A myoelectric hand splint.", "content": "A myoelectric hand splint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359593"}
{"pmid": "4359595", "title": "Isolation of an electrophoretically homogeneous glucomannan, using glutaraldehyde-insolubilised concanavalin A.", "content": "Isolation of an electrophoretically homogeneous glucomannan, using glutaraldehyde-insolubilised concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359595"}
{"pmid": "4359594", "title": "Photo-affinity labelling of carbohydrate-binding sites in proteins: synthesis of potential inhibitors.", "content": "Photo-affinity labelling of carbohydrate-binding sites in proteins: synthesis of potential inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359594"}
{"pmid": "4359597", "title": "Physiologic and pharmacologic roles for prostaglandins in obstetrics.", "content": "Physiologic and pharmacologic roles for prostaglandins in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359597"}
{"pmid": "4359598", "title": "Sound deprivation causes hypertension in rats.", "content": "Sound deprivation causes hypertension in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359598"}
{"pmid": "4359599", "title": "Early stages in estrogen control of gene expression and its derangement in cancer.", "content": "Early stages in estrogen control of gene expression and its derangement in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359599"}
{"pmid": "4359600", "title": "Microsomal membranes and the translational apparatus of eukaryotic cells.", "content": "Microsomal membranes and the translational apparatus of eukaryotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359600"}
{"pmid": "4359601", "title": "Solubilization and cellular fatty change.", "content": "Solubilization and cellular fatty change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359601"}
{"pmid": "4359602", "title": "Virologic and immunologic aspects of major oral ulcerations.", "content": "Virologic and immunologic aspects of major oral ulcerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359602"}
{"pmid": "4359603", "title": "Rare combinations of multiple primary tumours: report of two cases.", "content": "Rare combinations of multiple primary tumours: report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359603"}
{"pmid": "4359605", "title": "Bilateral granular cell myoblastoma of the lip: report of case.", "content": "Bilateral granular cell myoblastoma of the lip: report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359605"}
{"pmid": "4359604", "title": "A child with multiple congenital malformations and a 46,XX,t(Bq+;Dq-)-45,XX,-B,-D,+der(B),t(Bq+;Dq-) karyotype.", "content": "A child with multiple congenital malformations and a 46,XX,t(Bq+;Dq-)-45,XX,-B,-D,+der(B),t(Bq+;Dq-) karyotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359604"}
{"pmid": "4359608", "title": "Influence of hormone therapy on rats treated with the carcinogen ethylmethanesulphonate.", "content": "Influence of hormone therapy on rats treated with the carcinogen ethylmethanesulphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359608"}
{"pmid": "4359609", "title": "Analysis of morphophysiological developmental processes in mammalian brain.", "content": "Analysis of morphophysiological developmental processes in mammalian brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359609"}
{"pmid": "4359607", "title": "Water insoluble and soluble glucans produced by extracellular glycosyltransferases from Streptococcus mutans.", "content": "Water insoluble and soluble glucans produced by extracellular glycosyltransferases from Streptococcus mutans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359607"}
{"pmid": "4359622", "title": "The surgical treatment of occult insulinomas: a review of the problem.", "content": "The surgical treatment of occult insulinomas: a review of the problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359622"}
{"pmid": "4359620", "title": "Endocrine pancreatic islet disease with diarrhea. Report of a case due to diffuse hyperplasia of nonbeta islet tissue with a review of 54 additional cases.", "content": "Endocrine pancreatic islet disease with diarrhea. Report of a case due to diffuse hyperplasia of nonbeta islet tissue with a review of 54 additional cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359620"}
{"pmid": "4359619", "title": "Clinical evaluations of a histologic examination of the side effects of myelographic contrast media.", "content": "Clinical evaluations of a histologic examination of the side effects of myelographic contrast media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359619"}
{"pmid": "4359623", "title": "Preliminary experience of bone scanning with 99mTc-labelled polyphosphate in malignant disease.", "content": "Preliminary experience of bone scanning with 99mTc-labelled polyphosphate in malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359623"}
{"pmid": "4359624", "title": "Antiviral antibody responses in patients with renal diseases.", "content": "Antiviral antibody responses in patients with renal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359624"}
{"pmid": "4359626", "title": "Further evidence for the pool function of ubiquinone as derived from the inhibition of the electron transport by antimycin.", "content": "Further evidence for the pool function of ubiquinone as derived from the inhibition of the electron transport by antimycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359626"}
{"pmid": "4359625", "title": "Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study.", "content": "Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359625"}
{"pmid": "4359627", "title": "Structural properties of the creatine-kinase active site studied by chromophoric-reagent labelling.", "content": "Structural properties of the creatine-kinase active site studied by chromophoric-reagent labelling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359627"}
{"pmid": "4359628", "title": "Homology between enterotoxin protein and spore structural protein in Clostridium perfringens type A.", "content": "Homology between enterotoxin protein and spore structural protein in Clostridium perfringens type A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359628"}
{"pmid": "4359629", "title": "Precursor--product relationship of encephalomyocarditis virus-specific polypeptides. Comparisons by tryptic peptide mapping.", "content": "Precursor--product relationship of encephalomyocarditis virus-specific polypeptides. Comparisons by tryptic peptide mapping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359629"}
{"pmid": "4359630", "title": "Purification, subunit structure and properties of two repressible phosphohydrolases of Bacillus subtilis.", "content": "Purification, subunit structure and properties of two repressible phosphohydrolases of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359630"}
{"pmid": "4359644", "title": "Mutations in the L-arabinose operon of Escherichia coli B-r that result in hypersensitivity to catabolite repression.", "content": "Mutations in the L-arabinose operon of Escherichia coli B-r that result in hypersensitivity to catabolite repression. Two independent mutants resistant to l-arabinose inhibition only in the presence of d-glucose were isolated from an l-arabinose-sensitive strain containing the araD139 mutation. Preliminary mapping studies indicate that these mutations are closely linked to the araIOC region. Addition of d-glucose to growing cultures of these mutants results in a 95 to 98% repression of ara operon expression, as compared to a 50% repression of the parental control. Since cultures of both mutant and parental strains undergo a 50% repression of lac operon expression upon addition of glucose, the hypersensitivity to catabolite repression exhibited by these mutants is specific for the ara operon. Addition of cyclic adenosine monophosphate reverses the catabolite repression of the ara operon in both mutant and parent strains to 70 to 80% of the control. It is suggested that in these mutants the affinity of the ara operon initiator region for the cAMP-catabolite-activator protein complex may have been altered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359644"}
{"pmid": "4359636", "title": "Genetic polymorphisms in Finno-Ugrian populations. Finns, Lapps and Maris.", "content": "Genetic polymorphisms in Finno-Ugrian populations. Finns, Lapps and Maris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359636"}
{"pmid": "4359639", "title": "Polymorphic traits in peoples of Eastern Asia and the Pacific.", "content": "Polymorphic traits in peoples of Eastern Asia and the Pacific.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359639"}
{"pmid": "4359637", "title": "Investigation of genetic polymorphic traits in jews. A contribution to the study of population genetics.", "content": "Investigation of genetic polymorphic traits in jews. A contribution to the study of population genetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359637"}
{"pmid": "4359646", "title": "Derepressed levels of the isoleucine-valine and leucine enzymes in his T 1504, a strain of Salmonella typhimurium with altered leucine transfer ribonucleic acid.", "content": "Derepressed levels of the isoleucine-valine and leucine enzymes in his T 1504, a strain of Salmonella typhimurium with altered leucine transfer ribonucleic acid. A hisT mutant of Salmonella typhimurium was found to have altered regulation of the isoleucine-valine and leucine enzymes. These enzymes in the hisT strain were derepressed two- to eightfold over those of the parent wild-type strain when grown in minimal medium or under repressing conditions. The amount of tRNA(Leu) and the cellular concentration of charged tRNA(Leu) was about the same in the hisT strain and in the wild type. However, leucyl-tRNA from the mutant was chromatographically different from that of wild type, confirming previous reports that hisT strains have altered tRNA(Leu). These results suggest strongly that tRNA(Leu) is involved in repression of the isoleucine-valine and leucine enzymes in S. typhimurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359646"}
{"pmid": "4359647", "title": "Isolation and complementation of mutants in galactose taxis and transport.", "content": "Isolation and complementation of mutants in galactose taxis and transport. By using a new screening method, we have obtained 43 new Escherichia coli mutants defective in ring formation on galactose swarm plates, which score for defects in chemotaxis or transport. They were complemented and compared with mutations previously known to lie in the galactose-binding protein or the beta-methylgalactoside (mgl) permease, or both. The mutations were all found to lie in three genes, called mglA, mglB, and mglC. mglB codes for the gene specifying the binding protein. Based on co-transduction experiments, mglA, mglB, and mglC lie close to each other on the bacterial chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359647"}
{"pmid": "4359642", "title": "Thalassemia types among Kurdish Jews.", "content": "Thalassemia types among Kurdish Jews.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359642"}
{"pmid": "4359649", "title": "Ethylene glycol-induced alteration of conidial germination in Neurospora crassa.", "content": "Ethylene glycol-induced alteration of conidial germination in Neurospora crassa. In nutrient medium containing 3.22 M ethylene glycol or glycerol, conidia of Neurospora crassa grow as single cells, without forming the germ tubes characteristic of normal morphological germination. Ethylene glycol is more effective than glycerol in producing this response. After growth in ethylene glycol medium for a suitable time, the cells are easily disrupted by an abrupt decrease in osmotic pressure. Osmotic disruption yields intact nuclei and mitochondria, although mitochondrial fractions obtained in this way show significantly reduced concentrations of cytochromes c + c(1), as compared to those observed for comparable fractions obtained from vegetative hyphae. Cell cultures gradually adapted to lower concentrations of the glycol show a much higher degree of synchrony in the formation of germ tubes than do untreated conidia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359649"}
{"pmid": "4359648", "title": "Properties of mutants in galactose taxis and transport.", "content": "Properties of mutants in galactose taxis and transport. beta-Methylgalactoside (mgl) permease mutants of Escherichia coli, which are defective in three genes, mglA, mglB, and mglC, were assayed for galactose taxis and galactose transport. The mglB product is the galactose-binding protein. Previous evidence, supported by our new findings, shows that the galactose-binding protein is the recognition component for galactose taxis as well as for galactose transport. Most mutants defective in mglB showed strong effects on both chemotaxis and transport; however, a couple showed effects chiefly on one process or the other, thus allowing a separation of chemotaxis and transport. The mglA and mglC products have not yet been identified, but they must be components of the galactose transport machinery since mutants defective in mglA or mglC, or both, showed strongly reduced transport. Although some of these mutants showed little chemotaxis, most gave close to wild-type chemotactic responses. Thus, transport is not required for galactose taxis. The bacteria detect changes in the fraction of binding protein associated with galactose, not changes in the rate of transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359648"}
{"pmid": "4359641", "title": "Biochemical aspects of the pathogenesis of the thalassemia syndromes.", "content": "Biochemical aspects of the pathogenesis of the thalassemia syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359641"}
{"pmid": "4359645", "title": "Cyclic adenosine 3',5'-monophosphate and morphogenesis in Mucor racemosus.", "content": "Cyclic adenosine 3',5'-monophosphate and morphogenesis in Mucor racemosus. Yeastlike cells of Mucor racemosus grown under 100% CO(2) underwent morphogenesis to hyphae after exposure to air. The addition of dibutyryl cyclic adenosine monophosphate (dbcAMP) to yeastlike cultures inhibited this morphogenesis in media containing 2% glucose. The maintenance of uniformly spherical, budding cells required 1 mM dbcAMP in a defined medium containing Casamino Acids, and 3 mM dbcAMP in a medium containing yeast extract and peptone. At these concentrations, dbcAMP also induced yeastlike development in young aerobic hyphae grown in media containing 2% glucose. Removal of dbcAMP resulted in hyphal development. The endogenous cyclic AMP (cAMP) content of yeastlike cultures was measured after a shift from CO(2) to air. A fourfold decrease in intracellular cAMP preceded the appearance of hyphal germ tubes. These results indicate that cAMP plays a role in the control of morphogenesis in Mucor racemosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359645"}
{"pmid": "4359638", "title": "Studies of polymorphic traits for the characterization of populations. African populations south of the Sahara.", "content": "Studies of polymorphic traits for the characterization of populations. African populations south of the Sahara.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359638"}
{"pmid": "4359651", "title": "Genetic control of the 2-keto-3-deoxy-d-gluconate metabolism in Escherichia coli K-12: kdg regulon.", "content": "Genetic control of the 2-keto-3-deoxy-d-gluconate metabolism in Escherichia coli K-12: kdg regulon. 2-Keto-3-deoxy-gluconate (KDG), an intermediate of the hexuronate pathway in Escherichia coli K-12, is utilized as the sole carbon source only in strains derepressed for the specific KDG-uptake system. KDG is metabolized to pyruvate and glyceraldehyde-3-phosphate via the inducible enzymes KDG-kinase and 2-keto-3-deoxy-6-phosphate-gluconate (KDPG) aldolase. However, another inducible pathway, where the KDG is the branch point, has been demonstrated. Genetic studies of the KDG degradative pathway reported in this paper led to the location of KDG kinase-negative and pleiotropic constitutive mutations. The kdgK locus, presumably the structural gene of the kinase, occurs at min 69 and is co-transducible with xyl. The mutants, simultaneously constitutive for the uptake, kinase, and aldolase, define a kdgR locus at min 36 between the co-transducible markers kdgA and oldD. As to the nature of the control exerted by the kdgR product, we have shown the following. (i) Thermosensitive mutants of the kdgR locus are inducible at low temperature but derepressed at 42 C for the three operons-kdgT (transport system), kdgK, and kdgA (KDPG aldolase). (ii) The kdgR(+) allele is dominant to the kdgR constitutive allele. (iii) A deletion in kdgA extending into the regulatory gene, kdgR, leads to a constitutive expression of the nondeleted operons-kdgT and kdgK. These properties demonstrate that the kdg regulon is negatively controlled by the kdgR product. It is presumed that differences in operator and in promotor structures could explain the strong decoordination, respectively, in the induction and catabolic repression, of these three enzymes activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359651"}
{"pmid": "4359650", "title": "Residual polarity and transcription-translation coupling during recovery from chloramphenicol or fusidic acid.", "content": "Residual polarity and transcription-translation coupling during recovery from chloramphenicol or fusidic acid. Fusidic acid or chloramphenicol was used to inhibit peptide synthesis to 1% of normal in Escherichia coli B, strain AS19. After 10 min of inhibition, peptide synthesis could be quickly restored to 80% of the normal rate after washing the bacteria on a filter. However, even in the presence of adenosine 3'-5'-cyclic-monophosphoric acid to block catabolite repression, beta-galactosidase, the first enzyme of the lactose operon (lac), could only be induced to 10% of normal, and the last enzyme of the operon, galactoside acetyltransferase, even less. The first and last enzymes of the operon for tryptophan synthesis could be derepressed to about 30% of normal. The lac ribonucleic acid (RNA) induced during recovery showed a smaller than normal size distribution on sucrose gradients. The operator-proximal or -distal parts of this RNA were specifically labeled. Hybridization to phi80dlac deoxyribonucleic acid (DNA) suggested that although the distal parts of the lac RNA were barely detectable, initiation was occurring at normal rates in recovery. Either normal levels of distal messenger RNA (mRNA) are made but then rapidly degraded or the mRNA is not completed. The small amount that is made decayed abnormally slowly, probably as a result of slower transcription. Total mRNA decay was multiphasic with all components decaying slower than normal. We propose that there is a residual level of inhibition of peptide synthesis during recovery. The probability that a ribosome is blocked at any codon can be estimated from the data. The longer the message, the less likely its complete translation. We propose that the RNA polymerase can transcribe translatable mRNA for only a finite distance beyond the lead ribosome. Because ribosomes can load at the start of each message in a polycistronic mRNA, the probability that a distal message will be synthesized and translated is a function of the number of more proximal messages and the distances between their ribosome-loading sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359650"}
{"pmid": "4359652", "title": "Binding of streptococcal competence factor by the spheroplast membrane of a group H streptococcus.", "content": "Binding of streptococcal competence factor by the spheroplast membrane of a group H streptococcus. The binding of streptococcal competence factor (CF) was found to be specific for a strain of streptococcus which was capable of undergoing competence induction. Three other streptococcal strains which could not be induced to competence, did not bind CF. CF binding was independent of time, temperature, age of the culture, and type of growth media employed. Several observations indicated that the receptor sites for CF are located in the bacterial membrane: (i) the retention of CF by spheroplasts, (ii) the binding of CF by isolated membrane fractions, and (iii), the degradation of CF binding capacity of membranes by different chemicals and enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359652"}
{"pmid": "4359643", "title": "Globin synthesis in alpha- and beta-thalassemia.", "content": "Globin synthesis in alpha- and beta-thalassemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359643"}
{"pmid": "4359640", "title": "Distribution of certain polymorphic traits in populations of the Indian peninsula and South Asia.", "content": "Distribution of certain polymorphic traits in populations of the Indian peninsula and South Asia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359640"}
{"pmid": "4359635", "title": "Studies of polymorphic traits for the characterization of populations. The populations of Scandinavia.", "content": "Studies of polymorphic traits for the characterization of populations. The populations of Scandinavia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359635"}
{"pmid": "4359653", "title": "Histidyl-transfer ribonucleic acid synthetase in positive control of the histidine operon in Salmonella typhimurium.", "content": "Histidyl-transfer ribonucleic acid synthetase in positive control of the histidine operon in Salmonella typhimurium. Histidyl-transfer ribonucleic acid (tRNA) synthetase (HRS), coded by the hisS gene, appears to play two roles in regulation of the histidine operon of Salmonella typhimurium: (i) in synthesis of a critical effector molecule, histidyl-tRNA, and (ii) a more direct effect elicited by the presence of the enzyme protein itself. The specific activity of HRS was elevated either by mutations in the strB locus or in hisS(+) merodiploids of Escherichia coli/S. typhimurium and S. abony/S. typhimurium. In each case, an increase in HRS was accompanied by an increase in histidine operon expression, indicating that HRS may be involved in positive control of the histidine operon. It is unlikely that HRS leads to increased histidine operon expression merely by acting as a \"sponge\" for charged tRNA. Rather, HRS appears to influence operon expression by interaction with some effector molecule other than charged tRNA or by a direct interaction with the histidine operator-promoter region. The functional level of histidine operon expression has no effect on HRS specific activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359653"}
{"pmid": "4359654", "title": "Studies of respiratory components and oxidative phosphorylation in mitochondria of mi-1 Neurospora crassa.", "content": "Studies of respiratory components and oxidative phosphorylation in mitochondria of mi-1 Neurospora crassa. Oxidative phosphorylation has been demonstrated with mitochondria of the mi-1 respiratory mutant of Neurospora crassa. The P/O ratios observed with these mitochondria were approximately 0.8 with citrate and 0.4 with either externally added reduced nicotinamide adenine dinucleotide (NADH), succinate, or ascorbate-tetramethyl-p-phenylenediamine (TPD). These P/O ratios suggest that there are only two sites of phosphorylation in mitochondria isolated from young (20 to 24 h) cultures of the mi-1 mutant. The energy-dependent reduction of NAD(+) with succinate and the phosphorylation associated with ascorbate-TPD oxidation indicate that the first and the third sites of energy coupling are present in this mutant. Difference spectra of mitochondria from young cultures of the mi-1 mutant revealed the presence of cytochrome c. Cytochromes b and a + a(3) were not detected. However, in the presence of antimycin A, a small peak in the Soret region at 430 nm was observed. A carbon monoxide difference spectrum revealed the presence of a component of the respiratory chain with a spectrum similar to that of cytochrome o. It is of interest that respiratory inhibitors such as antimycin A, 2-n-nonylhydroxyquinoline N-oxide, and cyanide abolished phosphorylation but only partially inhibited oxidation. It is postulated that the mi-1 respiratory system contains two pathways of electron transport-the first is associated with a phosphorylating pathway, whereas the second is a non-phosphorylating electron transport pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359654"}
{"pmid": "4359655", "title": "D-lysine catabolic pathway in Pseudomonas putida: interrelations with L-lysine catabolism.", "content": "D-lysine catabolic pathway in Pseudomonas putida: interrelations with L-lysine catabolism. The isolation of several mutant strains blocked in l-lysine degradation has permitted an assessment of the physiological significance of enzymatic reactions related to lysine metabolism in Pseudomonas putida. Additional studies with intact cells involved labeling of metabolic intermediates from radioactive l- or d-lysine, and patterns of enzyme induction in both wild-type and mutant strains. These studies lead to the conclusions that from l-lysine, the obligatory pathway is via delta-aminovaleramide, delta-aminovalerate, glutaric semialdehyde, and glutarate, and that no alternative pathways from l-lysine exist in our strain. A distinct pathway from d-lysine proceeds via Delta(1)-piperideine-2-carboxylate, l-pipecolate, and Delta(1)-piperideine-6-carboxylate (alpha-aminoadipic semialdehyde). The two pathways are independent in the sense that certain mutants, unable to grow on l-lysine, grow at wild-type rates of d-lysine, utilizing the same intermediates as the wild type, as inferred from labeling studies. This finding implies that lysine racemase in our strain, while detectable in cell extracts, is not physiologically functional in intact cells at a rate that would permit growth of mutants blocked in the l-lysine pathway. Pipecolate oxidase, a d-lysine-related enzyme, is induced by d-lysine and less efficiently by l-lysine. Aminooxyacetate virtually abolishes the inducing activity of l-lysine for this enzyme, suggesting that lysine racemase, although functionally inactive for growth purposes, may still have regulatory significance in permitting cross-induction of d-lysine-related enzymes by l-lysine, and vice versa. This finding suggests a mechanism in bacteria for maintaining regulatory patterns in pathways that may have lost their capacity to support growth. In addition, enzymatic studies are reported which implicate Delta(1)-piperideine-2-carboxylate reductase as an early step in the d-lysine pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359655"}
{"pmid": "4359657", "title": "Further studies on the behavioural and biochemical interaction between caffeine and L-DOPA.", "content": "Further studies on the behavioural and biochemical interaction between caffeine and L-DOPA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359657"}
{"pmid": "4359656", "title": "Metabolism of D-arabinose by Escherichia coli B-r.", "content": "Metabolism of D-arabinose by Escherichia coli B-r. The pathway for d-arabinose metabolism in Escherichia coli B/r has been determined. Evidence is presented to support the following metabolic scheme: d-arabinose d-ribulose right harpoon-up d-ribulose-5-phosphate d-xylulose-5-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359656"}
{"pmid": "4359658", "title": "Antagonism by DL-threo-DOPS of the suppression of a conditioned avoidance response induced by a dopamine-beta-hydroxylase inhibitor.", "content": "Antagonism by DL-threo-DOPS of the suppression of a conditioned avoidance response induced by a dopamine-beta-hydroxylase inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359658"}
{"pmid": "4359662", "title": "The effects of perlapine on sleep.", "content": "The effects of perlapine on sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359662"}
{"pmid": "4359668", "title": "Development of cell lines after exposure of chicken embryonic fibroblasts to herpes simplex virus type 2 at supraoptimal temperature.", "content": "Development of cell lines after exposure of chicken embryonic fibroblasts to herpes simplex virus type 2 at supraoptimal temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359668"}
{"pmid": "4359667", "title": "Metal complex formation and its importance for enzyme regulation.", "content": "Metal complex formation and its importance for enzyme regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359667"}
{"pmid": "4359669", "title": "Herpes simplex virus latency in SV40 hamster tumour cells.", "content": "Herpes simplex virus latency in SV40 hamster tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359669"}
{"pmid": "4359671", "title": "Measurement of personal exposure to 1,1,1-trichloroethane and trichloroethylene using an inexpensive sampling device and battery-operated pump.", "content": "Measurement of personal exposure to 1,1,1-trichloroethane and trichloroethylene using an inexpensive sampling device and battery-operated pump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359671"}
{"pmid": "4359670", "title": "Inhibition of virus multiplication by partially hydrolysed RNA: a possible membrane-effect.", "content": "Inhibition of virus multiplication by partially hydrolysed RNA: a possible membrane-effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359670"}
{"pmid": "4359672", "title": "Standard quartz dq12 greater than 5 micro m for experimental pneumoconiosis research projects in the Federal Republic of Germany.", "content": "Standard quartz dq12 greater than 5 micro m for experimental pneumoconiosis research projects in the Federal Republic of Germany.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359672"}
{"pmid": "4359676", "title": "Tyrosine crystals in pleomorphic adenomas of the salivary gland.", "content": "Tyrosine crystals in pleomorphic adenomas of the salivary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359676"}
{"pmid": "4359677", "title": "Letter: Congenital mesoblastic nephroma.", "content": "Letter: Congenital mesoblastic nephroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359677"}
{"pmid": "4359678", "title": "Virus excretion in smallpox. 1. Excretion in the throat, urine, and conjunctiva of patients.", "content": "Virus excretion in smallpox. 1. Excretion in the throat, urine, and conjunctiva of patients. Excretion of virus in the throat, urine, and conjunctiva of smallpox patients was studied daily for 2-3 weeks after the onset of fever. The virus titre in the throat and urine of haemorrhagic and confluent cases was higher than in discrete cases. The duration of virus excretion was also greater in confluent cases than in discrete cases. Conjunctival swabs from all 12 smallpox patients with conjunctivitis were positive for virus. The duration and titre of virus excretion in the throat, urine, and conjunctiva of patients were not related to their age or sex and did not depend on whether or not they had received a primary vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359678"}
{"pmid": "4359679", "title": "Virus excretion in smallpox. 2. Excretion in the throats of household contacts.", "content": "Virus excretion in smallpox. 2. Excretion in the throats of household contacts. Throat swabs of 34 of 328 family contacts of 52 smallpox cases, examined 4-8 days after the onset of the disease in the family, were positive for variola virus. The log titre of virus per swab ranged from 2 to 3.95. A higher proportion of unvaccinated than of vaccinated contacts excreted the virus. Only 4 of the virus-positive contacts developed clinical smallpox; this occurred 5-7 days after their swabs were examined. Excretion of virus in the throats of these contacts, a few of whom were in the incubation period of the disease, suggests the possibility that they could have spread the infection. This possibility, if kept in mind, may help in tracing the source of infection or in determining the incubation period in a few instances when difficulty is experienced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359679"}
{"pmid": "4359680", "title": "Evaluation of virological laboratory methods for smallpox diagnosis.", "content": "Evaluation of virological laboratory methods for smallpox diagnosis. Between July 1966 and May 1972 the Vesicular Disease Laboratory, Center for Disease Control, Atlanta, Ga., USA, tested specimens from 849 suspected smallpox cases by at least 2 methods, electron microscopy and chick embryo chorioallantoic membrane (CAM) cultures. A smaller number of specimens was tested by each of 4 methods: electron microscopy, CAM culture, agar gel precipitation, and tissue culture. For specimens handled in the field the CAM culture method was less sensitive than electron microscopy because the adverse conditions often inactivated the virus. CAM cultures were valuable for identifying members of the poxvirus subgroups, however, particularly when supplemented by tissue culture. The agar gel precipitation test was the least sensitive but was of value in confirming the results of electron microscopy. The latter was highly effective for the diagnosis of varicella, but dependably identified only about half of the vaccinia infections; for vaccinia, the CAM technique was essential. The occurrence of human monkeypox cases in West Africa emphasized that the usual smallpox diagnostic methods were inadequate. More sophisticated tests, such as the rabbit dermal sensitivity test, are necessary for accurate diagnosis of these cases as monkeypox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359680"}
{"pmid": "4359684", "title": "Effects of insulin, glucagon and adrenocorticotrophin on the levels of corticosteroids, noradrenaline, adrenaline and ascorbic acid in the adrenal glands of cats.", "content": "Effects of insulin, glucagon and adrenocorticotrophin on the levels of corticosteroids, noradrenaline, adrenaline and ascorbic acid in the adrenal glands of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359684"}
{"pmid": "4359682", "title": "Metabolite synthesis by rat liver cells and rat liver mitochondria.", "content": "Metabolite synthesis by rat liver cells and rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359682"}
{"pmid": "4359681", "title": "Characterization of poliovirus isolates in Japan after the mass vaccination with live oral poliomyelitis vaccine (Sabin).", "content": "Characterization of poliovirus isolates in Japan after the mass vaccination with live oral poliomyelitis vaccine (Sabin). From 1962 to 1968, 127 poliovirus isolates (92 from clinical specimens and 35 from healthy subjects) were subjected to intratypic serodifferentiation by the modified Wecker and McBride techniques. The two techniques gave concordant results for 103 strains, 91 of which were classified as vaccine-like, 9 as nonvaccine-like, and 3 as intermediate; 20 were classified as vaccine-like by one technique and as intermediate by the other, and 4 as nonvaccine-like by one technique and as intermediate by the other. The origin of the nonvaccine-like strains is unknown, but it is unlikely that they had been circulating in the community long. An rct/40-marker test of the isolates revealed a higher positivity rate than that found in field trials of Sabin vaccine. The results indicate that wild poliovirus has been almost completely eradicated from Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359681"}
{"pmid": "4359685", "title": "The cyclic AMP content and karyotype of the somatic hybrids of mouse malignant and nonmalignant cells segregating in vivo and in vitro.", "content": "The cyclic AMP content and karyotype of the somatic hybrids of mouse malignant and nonmalignant cells segregating in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359685"}
{"pmid": "4359687", "title": "Cystosarcoma phyllodes--a study of 13 cases.", "content": "Cystosarcoma phyllodes--a study of 13 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359687"}
{"pmid": "4359686", "title": "A study of the relationship of virus-like particles and Australia antigen in liver.", "content": "A study of the relationship of virus-like particles and Australia antigen in liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359686"}
{"pmid": "4359673", "title": "Scleroma affecting the middle ear cavity with report of three cases.", "content": "Scleroma affecting the middle ear cavity with report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359673"}
{"pmid": "4359688", "title": "Alpha fetoprotein levels in women taking oral contraceptives.", "content": "Alpha fetoprotein levels in women taking oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359688"}
{"pmid": "4359675", "title": "Glomus jugulare tumors. II. A clinicopathologic analysis of the effects of radiotherapy.", "content": "Glomus jugulare tumors. II. A clinicopathologic analysis of the effects of radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359675"}
{"pmid": "4359689", "title": "Use of cyclofenil (Sexovid) to induce ovulation.", "content": "Use of cyclofenil (Sexovid) to induce ovulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359689"}
{"pmid": "4359690", "title": "Evaluation of endometrial biopsy in the cycle of conception.", "content": "Evaluation of endometrial biopsy in the cycle of conception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359690"}
{"pmid": "4359691", "title": "Sub-clinical endometrial inflammation and T-mycoplasma: a possible cause of human reproductive failure.", "content": "Sub-clinical endometrial inflammation and T-mycoplasma: a possible cause of human reproductive failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359691"}
{"pmid": "4359674", "title": "Anti-Epstein Barr virus antibody in nasopharyngeal carcinoma.", "content": "Anti-Epstein Barr virus antibody in nasopharyngeal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359674"}
{"pmid": "4359692", "title": "A modified in vitro spermatozoal penenetration test. I. Method.", "content": "A modified in vitro spermatozoal penenetration test. I. Method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359692"}
{"pmid": "4359693", "title": "A modified in vitro spermatozoal penetration test. II. Application in fertility investigations.", "content": "A modified in vitro spermatozoal penetration test. II. Application in fertility investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359693"}
{"pmid": "4359694", "title": "Clinical trial and laboratory investigation of a low-dose progestogen-only contraceptive--Exluton.", "content": "Clinical trial and laboratory investigation of a low-dose progestogen-only contraceptive--Exluton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359694"}
{"pmid": "4359695", "title": "Characteristics of infection by RSV. I. Non-requirement for the S phase of cellular DNA synthesis.", "content": "Characteristics of infection by RSV. I. Non-requirement for the S phase of cellular DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359695"}
{"pmid": "4359696", "title": "Characteristics of infection by RSV. II. Dependence on cell events which can occur in the G2 phase and after mitosis.", "content": "Characteristics of infection by RSV. II. Dependence on cell events which can occur in the G2 phase and after mitosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359696"}
{"pmid": "4359697", "title": "Studies on a heat-labile variola virus inhibitor in normal sera. I. Detection by the variola focus reduction assay and its general characteristics.", "content": "Studies on a heat-labile variola virus inhibitor in normal sera. I. Detection by the variola focus reduction assay and its general characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359697"}
{"pmid": "4359698", "title": "Studies on a heat-labile variola virus inhibitor in normal sera. II. Further characterization of the inhibitor and its activity.", "content": "Studies on a heat-labile variola virus inhibitor in normal sera. II. Further characterization of the inhibitor and its activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359698"}
{"pmid": "4359701", "title": "Migraines in childhood.", "content": "Migraines in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359701"}
{"pmid": "4359700", "title": "Factors associated with deterioration of kidney function in patients with spinal cord injury.", "content": "Factors associated with deterioration of kidney function in patients with spinal cord injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359700"}
{"pmid": "4359702", "title": "Chondroma of the tibia.", "content": "Chondroma of the tibia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359702"}
{"pmid": "4359704", "title": "Hyperlipidemia in experimental disseminated intravascular coagulation.", "content": "Hyperlipidemia in experimental disseminated intravascular coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359704"}
{"pmid": "4359703", "title": "Renal blood flow in the dog. Autoregulation and intrarenal distribution.", "content": "Renal blood flow in the dog. Autoregulation and intrarenal distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359703"}
{"pmid": "4359713", "title": "Studies on sedimentation characteristics of heterogeneous nuclear RNA.", "content": "Studies on sedimentation characteristics of heterogeneous nuclear RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359713"}
{"pmid": "4359712", "title": "Formation of choline from phospholipid precursors: a comparison of the enzymes involved in phospholipid catabolism in the brain of the rhesus monkey.", "content": "Formation of choline from phospholipid precursors: a comparison of the enzymes involved in phospholipid catabolism in the brain of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359712"}
{"pmid": "4359709", "title": "Inhibition of glycolytic metabolism and sleep-waking states in cats.", "content": "Inhibition of glycolytic metabolism and sleep-waking states in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359709"}
{"pmid": "4359714", "title": "Spin echo nuclear magnetic resonance in cancerous tissue.", "content": "Spin echo nuclear magnetic resonance in cancerous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359714"}
{"pmid": "4359699", "title": "The protein neurotoxins in scorpion and elapid snake venoms.", "content": "The protein neurotoxins in scorpion and elapid snake venoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359699"}
{"pmid": "4359716", "title": "Intra-arterial hepatography: experimental evaluation of a new contrast agent.", "content": "Intra-arterial hepatography: experimental evaluation of a new contrast agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359716"}
{"pmid": "4359715", "title": "Pharmacoangiography with angiotensin.", "content": "Pharmacoangiography with angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359715"}
{"pmid": "4359718", "title": "Poliovirus type 3 isolation from infants with respiratory diseases.", "content": "Poliovirus type 3 isolation from infants with respiratory diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359718"}
{"pmid": "4359720", "title": "A clinical approach to pain.", "content": "A clinical approach to pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359720"}
{"pmid": "4359722", "title": "Mixed leukocyte culture reactions with man-mouse hybrid cells.", "content": "Mixed leukocyte culture reactions with man-mouse hybrid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359722"}
{"pmid": "4359721", "title": "Cell-mediated antitumor immune reactions under syngeneic conditions.", "content": "Cell-mediated antitumor immune reactions under syngeneic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359721"}
{"pmid": "4359710", "title": "Drinking in the monkey evoked by nicotine or angiotensin II microinjected in hypothalamic and mesencephalic sites.", "content": "Drinking in the monkey evoked by nicotine or angiotensin II microinjected in hypothalamic and mesencephalic sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359710"}
{"pmid": "4359723", "title": "Virus plaque assay and enumeration of effector cells in mixed lymphocyte cultures.", "content": "Virus plaque assay and enumeration of effector cells in mixed lymphocyte cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359723"}
{"pmid": "4359724", "title": "Correlation of MLC reactivity after experimental and clinical transplantation. Virus and cytophilic antibody: sources of false negatives.", "content": "Correlation of MLC reactivity after experimental and clinical transplantation. Virus and cytophilic antibody: sources of false negatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359724"}
{"pmid": "4359726", "title": "Sensitivity of Azotobacter chroococcum to some antibiotics.", "content": "Sensitivity of Azotobacter chroococcum to some antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359726"}
{"pmid": "4359711", "title": "Sleep-waking patterns in cats after administration of fenfluramine and other monoaminergic modulating drugs.", "content": "Sleep-waking patterns in cats after administration of fenfluramine and other monoaminergic modulating drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359711"}
{"pmid": "4359729", "title": "Increased production of cyclic AMP in mechanically stressed alveolar bone in cats.", "content": "Increased production of cyclic AMP in mechanically stressed alveolar bone in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359729"}
{"pmid": "4359728", "title": "Reactive granular cells in sites of trauma. A cytochemical and ultrastructural study.", "content": "Reactive granular cells in sites of trauma. A cytochemical and ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359728"}
{"pmid": "4359731", "title": "Mitochondrial conformation and swelling-contraction reactivity during early liver regeneration.", "content": "Mitochondrial conformation and swelling-contraction reactivity during early liver regeneration. Studies of mitochondrial respiratory control and swelling contraction activity during early cell regeneration after partial hepatectomy have revealed a selective defect in the rate of substrate-supported, phosphate-induced mitochondrial swelling. Swelling profiles induced by Fe(2-) or Cu(2-) revealed no differences between sham-operated and partially hepatectomized mice, which suggests no defects in -SH group composition or ability to form lipid peroxides. The specific activity of mitochondrial cytochrome c oxidase was unchanged. There was no significant mitochondrial swelling in situ as determined from mitocrit and mitochondrial protein ratios. A significant decline in respiratory control and efficiency of oxidative phosphorylation was found in mitochondria from animals 8 and 24 hours after partial hepatectomy, partially reversed by bovine serum albumin. No significant change in ADP:O ratio was noted and the decrease in RCI was due primarily to a significant decline in state 3 respiration rate. In situ electron microscopic studies of mitochondria failed to reveal significant abnormalities during early cell regeneration apart from decrease in numbers of matrix granules, focal matrix rarefaction and predominance of round forms. Electron microscopic studies of mitochondria after in vitro phosphate-induced swelling experiments showed no differences between sham and partially hepatectomized animals, but revealed two distinct populations of mitochondria, the predominant form (type III) showing distortion, matrix lucency and outer membrane rupture. ATP induced a diminished reversal in light scattering in partially hepatectomized mitochondria even when examined at 20 minutes, manifested as an increase in numbers of orthodox mitochondrial forms at the expense of the swollen type III forms. The pathogenesis of the impaired respiratory control and phosphate-induced swelling is unknown, but analogous observations have been found in mitochondria harvested from cells in which abnormal accumulations of free fatty acids have been demonstrated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359731"}
{"pmid": "4359732", "title": "Formation of multinucleate giant cells in organized epitheloid cell granulomas.", "content": "Formation of multinucleate giant cells in organized epitheloid cell granulomas. Organized epithelioid cell granulomas were produced experimentally by injecting intradermally dilute suspensions of zirconium and beryllium salts into individuals who had been previously sensitized to these metals. Biopsies were obtained at intervals of between 5 days and 13 months later, and the specimens were fixed and prepared for light and electron microscopy. Tritiated thymidine was injected into a number of the granulomas; the biopsy specimens were secured from 40 minutes to 2 or more weeks later, and the tissues were processed for light microscopic autoradiography. Giant cells occurred commonly, both within organized tubercles and in relation to areas of necrosis, and had markedly different cytoplasmic features from typical secretory epithelioid cells which enabled them to be readily recognized at scanning magnifications. The characteristic hallmark of these giant cells was the presence of myriads of small mitochondria adjacent to nuclei with numerous membrane-lined vesicles in the center of the cell. Giant cells occurred mainly in edematous disrupted tubercles. In these tubercles, epithelioid cells contained cytoplasmic components more like giant cells. Direct evidence of cell fusion was not seen, although fusion of membranes seemed to occur between cells having similar cytoplasmic features. The failure to find labeled nuclei in any giant cells 40 minutes after injection of tritiated thymidine indicates that normal nuclear division does not occur within giant cells. We postulate that epithelioid cells containing vesicles develop in damaged and necrotic areas, and that mainly this type of epithelioid cell fuses to form giant cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359732"}
{"pmid": "4359730", "title": "Electron microscopic and chemical studies of the vascular changes and edema of lead encephalopathy. A comparative study of the human and experimental disease.", "content": "Electron microscopic and chemical studies of the vascular changes and edema of lead encephalopathy. A comparative study of the human and experimental disease. Lead encephalopathy was induced in suckling rats by administering lead to the mother. The brains were studied by light and electron microscopy, and the results were compared with observations in the human disease as well as in cases of cerebral ischemia in children. In their severe forms, both human and experimental lead encephalopathies are characterized by exudative extracellular edema and perivascular PAS-positive globules. The latter consist of osmiophilic non-membrane-limited cytoplasmic inclusions located, in the rat exclusively and in the human predominantly, in perivascular astrocytes. Intervascular strands are also found in both forms of the disease. In the rat these consist of basement membrane surrounding endothelial cytoplasm. Chemically, experimental lead encephalopathy with morphologically demonstrable edema is associated with an increase in brain water, sodium and serum albumin. Relative to the serum concentration, the increase in water is disproportionately greater than the sodium or albumin. There were no demonstrable changes in chloride or potassium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359730"}
{"pmid": "4359733", "title": "Separation of cells having histochemically demonstrable glucose-6-phosphatase from suspensions of hamster kidney cells in an isokinetic density gradient of Ficoll in tissue culture medium.", "content": "Separation of cells having histochemically demonstrable glucose-6-phosphatase from suspensions of hamster kidney cells in an isokinetic density gradient of Ficoll in tissue culture medium. Suspensions of enzymatically disaggregated hamster kidney cells were separated primarily according to differences in diameter using velocity sedimentation in a previously described isokinetic density gradient and according to differences in density in an isopycnic density gradient. Cells which contained histochemically demonstrable glucose-6-phosphatase were thought to be cells from proximal tubules and constituted 46.5 +/- 14.1% of the cells in the starting sample suspension of disaggregated kidney cells. The purest gradient fractions from experiments using velocity sedimentation contained 98.0 +/- 0.6% cells which demonstrated glucose-6-phosphatase activity. More than 99.0% of these cells excluded trypan blue. Isopycnic sedimentation was not an effective means of purifying proximal tubule cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359733"}
{"pmid": "4359734", "title": "Lesions of the islets of Langerhans in encephalomyocarditis virus-infected mice with diabetes mellitus-like disease. I. Acute lesions.", "content": "Lesions of the islets of Langerhans in encephalomyocarditis virus-infected mice with diabetes mellitus-like disease. I. Acute lesions. Mice infected with the M variant of the encephalomyocarditis (EMC) virus develop lesions of the islets of Langerhans associated with a diabetes mellitus-like disease. Ultrastructural alterations become evident in capillaries and beta cells at a time when large amounts of virus are present in the pancreatic tissue. Although some beta cells become necrotic, degranulation and contraction of intact cells is the prominent lesion. Changes in the capillaries appear early in the course of the infection and later are associated with interstitial fibrosis in and around the islets. During early convalescence, beta cells are degranulated and exhibit striking alterations of cytoplasmic organelles. These changes appear to be consequent to increased metabolic activity by the residual insular tissue. Interestingly enough, specific lesions of the alpha cells are not observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359734"}
{"pmid": "4359736", "title": "Clinical evaluation of live, oral types 1, 2, and 5 adenovirus vaccines.", "content": "Clinical evaluation of live, oral types 1, 2, and 5 adenovirus vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359736"}
{"pmid": "4359735", "title": "Histopathology of early myocardial infarcts. A new approach.", "content": "Histopathology of early myocardial infarcts. A new approach. The histopathology of human myocardial infarcts is reviewed in a series of 46 cases ranging from sudden death to a clinical age of 3 days. A set of histopathologic features is described whereby the diagnosis of acute myocardial infarction can be made, even in cases of sudden death, on routine sections and even after considerable autolysis. This is primarily a stretching and waviness of the myocardial fibers, especially at the border of the infarcted area. Its mechanism is probably twofold: the rythmical pull exerted by the normal myocardium against the infarcted paralyzed area and the outward bulging of this area at every systole. On the basis of human material alone, it may be inferred that this pattern develops very rapidly: surely less than 1 hour and perhaps a few minutes after the local circulation has failed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359735"}
{"pmid": "4359738", "title": "Airways function during mild viral respiratory illnesses. The effect of rhinovirus infection in cigarette smokers.", "content": "Airways function during mild viral respiratory illnesses. The effect of rhinovirus infection in cigarette smokers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359738"}
{"pmid": "4359737", "title": "Moderate ethanol ingestion and plasma triglyceride levels. A study in normal and hypertriglyceridemic persons.", "content": "Moderate ethanol ingestion and plasma triglyceride levels. A study in normal and hypertriglyceridemic persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359737"}
{"pmid": "4359740", "title": "Hypercalcemia in bronchogenic carcinoma. A prospective study of 200 patients.", "content": "Hypercalcemia in bronchogenic carcinoma. A prospective study of 200 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359740"}
{"pmid": "4359739", "title": "1,25 Dihydroxy-vitamin D3 in normal man and patients with renal failure.", "content": "1,25 Dihydroxy-vitamin D3 in normal man and patients with renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359739"}
{"pmid": "4359741", "title": "Letter: Hypercalcemia and streptozotocin.", "content": "Letter: Hypercalcemia and streptozotocin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359741"}
{"pmid": "4359742", "title": "Letter: Hypercalcemia and streptozotocin. In comment.", "content": "Letter: Hypercalcemia and streptozotocin. In comment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359742"}
{"pmid": "4359744", "title": "Electron spinal resonance analysis of the nitroxide spin label 2,2,6,6-tetramethylpipidone-N-oxyl (Tempone) in single crystals of the reduced Tempone matrix.", "content": "Electron spinal resonance analysis of the nitroxide spin label 2,2,6,6-tetramethylpipidone-N-oxyl (Tempone) in single crystals of the reduced Tempone matrix. The nitroxide spin label Tempone (2,2,6,6-tetramethylpiperidone-N-oxyl) can be reduced with ascorbic acid to give a nonparamagnetic species. Single crystals of reduced Tempone serve as a suitable host matrix to orient trace quantities of Tempone for ESR analysis. In these crystals the majority of the Tempone molecules are well-oriented, but a smaller fraction of the molecules tumble freely to give an isotropic electron spin resonance (ESR) spectrum. ESR transitions for the oriented molecules are saturated at much lower microwave power levels than for the tumbling molecules. For the oriented molecules, an analysis of the anisotropy of the spectroscopic splitting factor (g) gives principal values of g(1) = 2.0094, g(2) = 2.0061, g(3) = 2.0021. The hyperfine coupling tensor is nearly axially symmetric, with principal values (in gauss) of A(1) = 6.5, A(2) = 6.7, A(3) = 33.0. Within experimental error, the principal axis systems for the g tensor and the hyperfine tensor are identical. Comparison of the average values of g and A with the isotropic values of these parameters for Tempone in solvents of different polarity suggests a method for choosing the most appropriate tensor elements to be used for spin label experiments in various solvent systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359744"}
{"pmid": "4359743", "title": "Sequential enzymolysis of ligament and resultant stress-strain behavior.", "content": "Sequential enzymolysis of ligament and resultant stress-strain behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359743"}
{"pmid": "4359745", "title": "Electrochemical properties of hydrated cation-selective glass membrane. A model of K+ and Na+ transport.", "content": "Electrochemical properties of hydrated cation-selective glass membrane. A model of K+ and Na+ transport. Electrochemical properties of cation-selective glass microelectrodes made from NAS(27-04) were studied. There was a marked fall in electrical resistance of the microelectrodes stored in 3 M KCl solution (aging). The resistance was in the range of 2 x 10(7) to 10(9) Omega, which were much lower than those estimated from the electrical resistivity of dry glass for the equivalent dimensions of microelectrode working tips. This fall in resistance was accompanied by an increase in microelectrode selectivity for K(+). The low resistance and increased K(+) selectivity are desirable features that make the microelectrode more suitable for application to biologic studies. The changes in microelectrode resistance and selectivity were interpreted to be due to hydration of the entire thickness of the glass membrane, resulting in a change in the field strength of anionic sites and formation of ionic channels in the glass membrane. Thus, the fall in resistance is explained by decrease in energy barrier, which is equivalent to the activation energy of interaction between the cations and anionic sites in the glass membrane. Some of the microelectrodes showed a transient depolarization that resembled the action potential of a biological membrane. This transient depolarization was associated with the changes in microelectrode resistance and selectivity. The transient depolarizations suggest the temporary development of wide channels in the membrane permitting free movement of hydrated cations according to the bulk electrochemical gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359745"}
{"pmid": "4359747", "title": "Letter: Type IV hyperlipidaemia in cord blood.", "content": "Letter: Type IV hyperlipidaemia in cord blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359747"}
{"pmid": "4359746", "title": "Plasma testosterone: an accurate monitor of hormone treatment in prostatic cancer.", "content": "Plasma testosterone: an accurate monitor of hormone treatment in prostatic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359746"}
{"pmid": "4359748", "title": "The effect of diphenylhydantoin on insulin response.", "content": "The effect of diphenylhydantoin on insulin response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359748"}
{"pmid": "4359749", "title": "Affinity of calciferol analogues for 25-hydroxycholecalciferol receptors.", "content": "Affinity of calciferol analogues for 25-hydroxycholecalciferol receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359749"}
{"pmid": "4359750", "title": "Effects of angiotensin on plasma electrolyte concentrations in rabbits and in man.", "content": "Effects of angiotensin on plasma electrolyte concentrations in rabbits and in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359750"}
{"pmid": "4359751", "title": "Proceedings: Pressor sensitivity to angiotensin II in relation to sodium.", "content": "Proceedings: Pressor sensitivity to angiotensin II in relation to sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359751"}
{"pmid": "4359752", "title": "The effect of modifying the combination of insulin with rat adipose cells on the intracellular levels of cyclic AMP.", "content": "The effect of modifying the combination of insulin with rat adipose cells on the intracellular levels of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359752"}
{"pmid": "4359753", "title": "The effect of a distant reparative process on rat liver function.", "content": "The effect of a distant reparative process on rat liver function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359753"}
{"pmid": "4359754", "title": "Effects of sodium, angiotensin, and steroids on vascular reactivity in man.", "content": "Effects of sodium, angiotensin, and steroids on vascular reactivity in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359754"}
{"pmid": "4359755", "title": "Derivation of TK- clones from revertant TK+ mammalian cells.", "content": "Derivation of TK- clones from revertant TK+ mammalian cells. In order to obtain a large collection of Chinese hamster cell clones defective in thymidine kinase (TK(-)), BrdU(r) selection experiments have been performed on wild-type and revertant TK(+) cell lines. No clones (< 10(-9)) were obtained from the wild-type TK(+) cell line by single-step selection. In contrast, revertant TK(+) clones readily gave rise to stable TK(-) derivatives (1 - 2 x 10(-4)). Both wild-type and revertant TK(+) clones spontaneously yielded 8-AG(r) colonies with the same frequency (1 - 5 x 10(-6)), suggesting that the differences between wild-type and revertant cell lines specifically affected selection of the TK(-) phenotype. The increased frequency of TK(-) clones reflects perhaps the number (ploidy) or character of the autosomal TK loci in TK(+) revertants, or perhaps the mechanisms which regulate expression of the TK genes. Several mutagens, EMS, MNNG and UV, stimulated the TK(+) revertants' frequency of TK(-) subclones only slightly (< 3-fold). Biochemical and genetic data indicated that the TK(-) clones derived from one revertant are phenotypically different. The phenotypes displayed by these cell lines are stable and do not depend upon the continued presence of the selective agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359755"}
{"pmid": "4359756", "title": "Low gene variation in Drosophila busckii.", "content": "Low gene variation in Drosophila busckii. Study of allozyme variation in D. busckii at thirty loci gives the proportion of polymorphic loci =.166 and the proportion of loci heterozygous per individual =.044. D. busckii has a narrower seasonal and food niche than the other domestic species D. melanogaster which has more allozyme variation. It is suggested that the low gene variation in D. busckii might be due to adaptation of this species to a narrow niche.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359756"}
{"pmid": "4359757", "title": "Defective virions of herpes simplex viruses.", "content": "Defective virions of herpes simplex viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359757"}
{"pmid": "4359759", "title": "In vitro transcriptase activity of vesicular stomatitis virus B and T particles: analysis of product.", "content": "In vitro transcriptase activity of vesicular stomatitis virus B and T particles: analysis of product.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359759"}
{"pmid": "4359758", "title": "Resistance of hamster cells transformed by herpes simplex virus type 2 to superinfection by herpes simplex viruses.", "content": "Resistance of hamster cells transformed by herpes simplex virus type 2 to superinfection by herpes simplex viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359758"}
{"pmid": "4359761", "title": "Biochemical and biophysical characterization of calicivirus isolates from pinnipeds.", "content": "Biochemical and biophysical characterization of calicivirus isolates from pinnipeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359761"}
{"pmid": "4359762", "title": "Agglutinability of Rous cells by concanavalin A: study with a temperature-sensitive RSV mutant and inhibitors of macromolecular synthesis.", "content": "Agglutinability of Rous cells by concanavalin A: study with a temperature-sensitive RSV mutant and inhibitors of macromolecular synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359762"}
{"pmid": "4359760", "title": "Control of gene expression in rat cells transformed by a cold-sensitive murine sarcoma virus (MSV) mutant.", "content": "Control of gene expression in rat cells transformed by a cold-sensitive murine sarcoma virus (MSV) mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359760"}
{"pmid": "4359763", "title": "Differential phosphorylation and turnover of nuclear acidic proteins during the cell cycle of synchronized HeLa cells.", "content": "Differential phosphorylation and turnover of nuclear acidic proteins during the cell cycle of synchronized HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359763"}
{"pmid": "4359764", "title": "Binding of adenosine diphosphate by isolated membranes from human platelets.", "content": "Binding of adenosine diphosphate by isolated membranes from human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359764"}
{"pmid": "4359765", "title": "Fish liver fructose 1,6-diphosphatase. 3. The effect of temperature on the regulatory properties of the carp (Cyprinus carpio) liver enzyme.", "content": "Fish liver fructose 1,6-diphosphatase. 3. The effect of temperature on the regulatory properties of the carp (Cyprinus carpio) liver enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359765"}
{"pmid": "4359766", "title": "Nuclear protein kinases. Evidence for their heterogeneity, tissue specificity, substrate specificities, and differential responses to cyclic adenosine 3':5'-monophosphate.", "content": "Nuclear protein kinases. Evidence for their heterogeneity, tissue specificity, substrate specificities, and differential responses to cyclic adenosine 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359766"}
{"pmid": "4359767", "title": "Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.", "content": "Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359767"}
{"pmid": "4359768", "title": "Near ultraviolet circular dichroism and absorption spectra of chicken ovomucoid and acetylated derivatives at 297 and 77 degrees K.", "content": "Near ultraviolet circular dichroism and absorption spectra of chicken ovomucoid and acetylated derivatives at 297 and 77 degrees K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359768"}
{"pmid": "4359769", "title": "Properties of angiotensin II receptors in the bovine and rat adrenal cortex.", "content": "Properties of angiotensin II receptors in the bovine and rat adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359769"}
{"pmid": "4359770", "title": "Nuclear deoxyribonucleic acid polymerase. Purification and properties of the homogeneous enzyme from human KB cells.", "content": "Nuclear deoxyribonucleic acid polymerase. Purification and properties of the homogeneous enzyme from human KB cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359770"}
{"pmid": "4359771", "title": "Induction of delta-aminolevulinic acid synthetase in isolated rat liver cell suspensions. Adenosine 3':5'-monophosphate dependence of induction by drugs.", "content": "Induction of delta-aminolevulinic acid synthetase in isolated rat liver cell suspensions. Adenosine 3':5'-monophosphate dependence of induction by drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359771"}
{"pmid": "4359772", "title": "Induced reoxidation and reactivation of a reduced uridine diphosphate galactose-4-epimerase complex.", "content": "Induced reoxidation and reactivation of a reduced uridine diphosphate galactose-4-epimerase complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359772"}
{"pmid": "4359773", "title": "Molecular basis of the biological function of molybdenum. Effect of tungsten on xanthine oxidase and sulfite oxidase in the rat.", "content": "Molecular basis of the biological function of molybdenum. Effect of tungsten on xanthine oxidase and sulfite oxidase in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359773"}
{"pmid": "4359774", "title": "The metabolism of cyclopropane fatty acids by Tetrahymena pyriformis.", "content": "The metabolism of cyclopropane fatty acids by Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359774"}
{"pmid": "4359775", "title": "Evidence for randon distribution and translational movement of cytochrome b5 in endoplasmic reticulum.", "content": "Evidence for randon distribution and translational movement of cytochrome b5 in endoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359775"}
{"pmid": "4359776", "title": "Structural analyses of mammalian ribosomal ribonucleic acid and its precursors. The distribution of polypyrimidine sequences in ribosomal 28 S ribonucleic acid.", "content": "Structural analyses of mammalian ribosomal ribonucleic acid and its precursors. The distribution of polypyrimidine sequences in ribosomal 28 S ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359776"}
{"pmid": "4359777", "title": "Anomeric specificity of the alkaline form of fructose 1,6-diphosphatase from rabbit liver.", "content": "Anomeric specificity of the alkaline form of fructose 1,6-diphosphatase from rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359777"}
{"pmid": "4359778", "title": "Multiple forms of flounder muscle glyceraldehyde 3-phosphate dehydrogenase. Subunit composition, properties, and tissue distribution of the forms.", "content": "Multiple forms of flounder muscle glyceraldehyde 3-phosphate dehydrogenase. Subunit composition, properties, and tissue distribution of the forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359778"}
{"pmid": "4359779", "title": "Communication: Coacervation of tropoelastin results in fiber formation.", "content": "Communication: Coacervation of tropoelastin results in fiber formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359779"}
{"pmid": "4359780", "title": "Induction of cellular immunity to herpes simplex virus: relationship to the humoral immune response.", "content": "Induction of cellular immunity to herpes simplex virus: relationship to the humoral immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359780"}
{"pmid": "4359781", "title": "Host response to tumor-associated fetal antigens.", "content": "Host response to tumor-associated fetal antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359781"}
{"pmid": "4359782", "title": "In vitro immune stimulation-inhibition to spontaneous canine tumors of various histologic types.", "content": "In vitro immune stimulation-inhibition to spontaneous canine tumors of various histologic types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359782"}
{"pmid": "4359783", "title": "In vitro study of antiviral activity of immune spleen cells in experimental Venezuelan equine encephalomyelitis infection in mice.", "content": "In vitro study of antiviral activity of immune spleen cells in experimental Venezuelan equine encephalomyelitis infection in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359783"}
{"pmid": "4359784", "title": "The production of interferon by malignant plasma cells from patients with multiple myeloma.", "content": "The production of interferon by malignant plasma cells from patients with multiple myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359784"}
{"pmid": "4359785", "title": "Acid lability of rhinoviruses: loss of C and D antigenicity after treatment at pH 3.0.", "content": "Acid lability of rhinoviruses: loss of C and D antigenicity after treatment at pH 3.0.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359785"}
{"pmid": "4359786", "title": "Immunochemical quantitation of cell bound C4.", "content": "Immunochemical quantitation of cell bound C4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359786"}
{"pmid": "4359788", "title": "A basis for extracellular current density analysis in cerebellar cortex.", "content": "A basis for extracellular current density analysis in cerebellar cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359788"}
{"pmid": "4359787", "title": "In vivo suppression by cholera toxin of cell-mediated and foreign body inflammatory responses.", "content": "In vivo suppression by cholera toxin of cell-mediated and foreign body inflammatory responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359787"}
{"pmid": "4359789", "title": "Organization of vestibular nystagmus in oblique oculomotor system.", "content": "Organization of vestibular nystagmus in oblique oculomotor system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359789"}
{"pmid": "4359791", "title": "Identification of unitary potentials in turtle cerebellum and correlations with structures in granular layer.", "content": "Identification of unitary potentials in turtle cerebellum and correlations with structures in granular layer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359791"}
{"pmid": "4359790", "title": "Observations on phase-sensitive neurons of anteroventral cochlear nucleus of the cat: nonlinearity of cochlear output.", "content": "Observations on phase-sensitive neurons of anteroventral cochlear nucleus of the cat: nonlinearity of cochlear output.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359790"}
{"pmid": "4359793", "title": "Hepatic ultrastructural changes in murine lupinosis.", "content": "Hepatic ultrastructural changes in murine lupinosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359793"}
{"pmid": "4359792", "title": "Response characteristics of single units in the rat's trigeminal nuclei to vibrissa displacements.", "content": "Response characteristics of single units in the rat's trigeminal nuclei to vibrissa displacements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359792"}
{"pmid": "4359794", "title": "Ultrastructure of the alveolar-capillary wall in mitral stenosis.", "content": "Ultrastructure of the alveolar-capillary wall in mitral stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359794"}
{"pmid": "4359795", "title": "Cell death in the normal neonatal rat adrenal cortex.", "content": "Cell death in the normal neonatal rat adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359795"}
{"pmid": "4359797", "title": "An ultrastructural study of the effect of ultrasound on arterial tissue.", "content": "An ultrastructural study of the effect of ultrasound on arterial tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359797"}
{"pmid": "4359796", "title": "Studies on the pathogenesis of corneal arcus formation. I. The human corneal arcus and its relation to atherosclerosis as studied by immunofluorescence.", "content": "Studies on the pathogenesis of corneal arcus formation. I. The human corneal arcus and its relation to atherosclerosis as studied by immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359796"}
{"pmid": "4359798", "title": "Poliovirus antibody in urban school children.", "content": "Poliovirus antibody in urban school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359798"}
{"pmid": "4359799", "title": "Antibody titers to polioviruses in patients ten years after immunization with sabin vaccine.", "content": "Antibody titers to polioviruses in patients ten years after immunization with sabin vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359799"}
{"pmid": "4359800", "title": "Wilms' tumor metastasis to uncommon sites.", "content": "Wilms' tumor metastasis to uncommon sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359800"}
{"pmid": "4359803", "title": "Fever and petechiae with adenovirus type 7 infection.", "content": "Fever and petechiae with adenovirus type 7 infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359803"}
{"pmid": "4359808", "title": "Responsiveness to flickering light in waking and sleeping infants.", "content": "Responsiveness to flickering light in waking and sleeping infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359808"}
{"pmid": "4359809", "title": "A micromethod for the measurement of human plasma renin activity.", "content": "A micromethod for the measurement of human plasma renin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359809"}
{"pmid": "4359810", "title": "Plasma renin activity in the newly born and in young infants.", "content": "Plasma renin activity in the newly born and in young infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359810"}
{"pmid": "4359811", "title": "N-acetyl-2-O-methyl-tyrosine-oxytocin: a specific antagonist of oxytocin.", "content": "N-acetyl-2-O-methyl-tyrosine-oxytocin: a specific antagonist of oxytocin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359811"}
{"pmid": "4359805", "title": "Drinking elicited by intracranial microinjection of angiotensin in the cat.", "content": "Drinking elicited by intracranial microinjection of angiotensin in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359805"}
{"pmid": "4359812", "title": "Treatment of chondritis in the burned ear by the local instillation of antibiotics.", "content": "Treatment of chondritis in the burned ear by the local instillation of antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359812"}
{"pmid": "4359813", "title": "Congenital epulis tumor. Case report.", "content": "Congenital epulis tumor. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359813"}
{"pmid": "4359804", "title": "6-OHDA lesions of the hypothalamus: interaction of aphagia, food palatability, set-point for weight regulation, and recovery of feeding.", "content": "6-OHDA lesions of the hypothalamus: interaction of aphagia, food palatability, set-point for weight regulation, and recovery of feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359804"}
{"pmid": "4359814", "title": "Persistence of abnormal REM sleep response to ethanol as a result of previous ethanol ingestion.", "content": "Persistence of abnormal REM sleep response to ethanol as a result of previous ethanol ingestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359814"}
{"pmid": "4359807", "title": "Taming effect of nonnarcotic analgesics on the septal syndrome in rats.", "content": "Taming effect of nonnarcotic analgesics on the septal syndrome in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359807"}
{"pmid": "4359815", "title": "Persistence of cadmium-induced metabolic changes in liver and kidney.", "content": "Persistence of cadmium-induced metabolic changes in liver and kidney. Daily intraperitoneal injection of cadmium chloride (1 milligram per kilogram) for 45 days enhanced gluconeogenesis as evidenced by significant increases in the activities of liver and kidney cortex pyruvate carboxylase, phosphopyruvate carboxylase, hexosediphosphatase, and glucose-6-phosphatase, the quartet of key, rate-limiting enzymes involved in the biotransformation of noncarbohydrate precursors into glucose. Whereas cadmium treatment decreased the level of hepatic glycogen, the concentration of blood glucose and urea was significantly elevated by this heavy metal. Discontinuation of the heavy metal treatment for 28 days, in rats previously injected with cadmium for 45 days, failed to restore the observed biochemical alterations in hepatic and renal carbohydrate metabolism to control values. Evidence indicates that cadmium augments the glucose-synthesizing capacity of liver and kidney cortex and that various metabolic changes persist even after a 4-week period of withdrawal from exposure to the heavy metal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359815"}
{"pmid": "4359806", "title": "Lever-pressing behavior caused by intraseptal angiotensin II in water satiated rats.", "content": "Lever-pressing behavior caused by intraseptal angiotensin II in water satiated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359806"}
{"pmid": "4359816", "title": "Intravenous infusion of hydrochloric acid for treatment of severe metabolic alkalosis.", "content": "Intravenous infusion of hydrochloric acid for treatment of severe metabolic alkalosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359816"}
{"pmid": "4359817", "title": "Cold lymphocytotoxins in infections and parasitic infestations.", "content": "Cold lymphocytotoxins in infections and parasitic infestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359817"}
{"pmid": "4359823", "title": "Bacterial pneumonia complicating adenoviral pneumonia. A comparison of respiratory tract bacterial culture sources and effectiveness of chemoprophylaxis against bacterial pneumonia.", "content": "Bacterial pneumonia complicating adenoviral pneumonia. A comparison of respiratory tract bacterial culture sources and effectiveness of chemoprophylaxis against bacterial pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359823"}
{"pmid": "4359824", "title": "Diagnostic and surgical aspects of insulinoma. A review of twenty-seven cases.", "content": "Diagnostic and surgical aspects of insulinoma. A review of twenty-seven cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359824"}
{"pmid": "4359825", "title": "Studies on clonazepam, flunitrazepam, and related benzodiazepines in cat and monkey.", "content": "Studies on clonazepam, flunitrazepam, and related benzodiazepines in cat and monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359825"}
{"pmid": "4359826", "title": "Effect of prostaglandin F2alpha on responses on vascular smooth muscle to serotonin, angiotensin and epinephrine.", "content": "Effect of prostaglandin F2alpha on responses on vascular smooth muscle to serotonin, angiotensin and epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359826"}
{"pmid": "4359818", "title": "Complement-fixing antibodies to the AD-169 strain of cytomegalovirus in banked blood.", "content": "Complement-fixing antibodies to the AD-169 strain of cytomegalovirus in banked blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359818"}
{"pmid": "4359827", "title": "Subcutaneous mastectomy and immediate prosthetic implantation as an alternative to simple mastectomy.", "content": "Subcutaneous mastectomy and immediate prosthetic implantation as an alternative to simple mastectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359827"}
{"pmid": "4359829", "title": "Fibrinous pseudointimas within impermeable silastic-nylon velour. I. Ultrastructure of cell components at initial stages and cell population changes in the earlier pseudointima.", "content": "Fibrinous pseudointimas within impermeable silastic-nylon velour. I. Ultrastructure of cell components at initial stages and cell population changes in the earlier pseudointima.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359829"}
{"pmid": "4359831", "title": "Registers and registries: a review.", "content": "Registers and registries: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359831"}
{"pmid": "4359832", "title": "Immunization during pregnancy against poliomyelitis and influenza in relation to childhood malignancy.", "content": "Immunization during pregnancy against poliomyelitis and influenza in relation to childhood malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359832"}
{"pmid": "4359833", "title": "Peculiar lipid inclusions in the hepatic parenchymal cell of a patient with hereditary spherocytosis.", "content": "Peculiar lipid inclusions in the hepatic parenchymal cell of a patient with hereditary spherocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359833"}
{"pmid": "4359834", "title": "Stimulation of phagocytic release of neutral protease from human neutrophils by cholinergic amines and cyclic 3',5'-guanosine monophosphate.", "content": "Stimulation of phagocytic release of neutral protease from human neutrophils by cholinergic amines and cyclic 3',5'-guanosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359834"}
{"pmid": "4359835", "title": "Letter: Prevention of postsurgical ulnar neuropathy.", "content": "Letter: Prevention of postsurgical ulnar neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359835"}
{"pmid": "4359836", "title": "Homozygous type II hyperlipoproteinemia treatment. Partial ileal bypass in two children.", "content": "Homozygous type II hyperlipoproteinemia treatment. Partial ileal bypass in two children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359836"}
{"pmid": "4359837", "title": "Ear piercing and hepatitis. Nonsterile instruments for ear piercing and the subsequent onset of viral hepatitis.", "content": "Ear piercing and hepatitis. Nonsterile instruments for ear piercing and the subsequent onset of viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359837"}
{"pmid": "4359839", "title": "Ovarian tumors. Tumors and tumor-like conditions of the ovaries, fallopian tubes and ligaments of the uterus.", "content": "Ovarian tumors. Tumors and tumor-like conditions of the ovaries, fallopian tubes and ligaments of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359839"}
{"pmid": "4359841", "title": "The baboon. Microbiology, clinical chemistry and some hematological aspects.", "content": "The baboon. Microbiology, clinical chemistry and some hematological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359841"}
{"pmid": "4359843", "title": "NIMH-sponsored chemical synthesis program.", "content": "NIMH-sponsored chemical synthesis program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359843"}
{"pmid": "4359848", "title": "Forty-day fever. An epidemic of cytomegalovirus disease in a renal transplant population.", "content": "Forty-day fever. An epidemic of cytomegalovirus disease in a renal transplant population. An epidemic of cytomegalovirus disease (CMV) occurred in 38 percent of 34 renal transplant recipients during an 18-month period. A characteristic clinical pattern was noted: 40 days following transplantation, daily fevers recurred for periods of four to six weeks. This fever in conjunction with a diffuse interstitial pneumonitis and impaired hepatic and renal function constituted a diagnostic tetrad. Of all the laboratory techniques, throat and urine cultures were the most consistent in confirming the diagnosis. Analysis of the epidemic implicated the communal hemodialysis unit as the source of exposure to the virus. CMV was not seen in the first 86 patients who received transplants in the program, but with increasing use of hemodialysis, the percentage of patients with positive serologic reaction for CMV increased dramatically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359848"}
{"pmid": "4359847", "title": "Mixed mesodermal tumors of the uterus.", "content": "Mixed mesodermal tumors of the uterus. Two of five women with mixed mesodermal tumor of the uterus are well more than ten years after therapy. A third was well when last seen two years after therapy and died at age 84 but autopsy was not done. Review of the literature and the reported experience indicates that this diagnosis should be suspected more often. Since histologic features may vary from one place to another within the lesion, accurate assessment requires examination of adequate specimens of the tumor. The mere presence of heterologous elements in an endometrial carcinoma changes the five-year survival rate from 85 percent to less than 35 percent. While total abdominal hysterectomy with bilateral salpingo-oophorectomy is mandatory, radiation therapy should be added more often than in the past, as it has been clearly shown that many of these tumors are radiosensitive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359847"}
{"pmid": "4359849", "title": "Specialty conference: potpourri of adenoviral infections.", "content": "Specialty conference: potpourri of adenoviral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359849"}
{"pmid": "4359850", "title": "The ubiquitous adenovirus.", "content": "The ubiquitous adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359850"}
{"pmid": "4359851", "title": "Effect of hyper- and hypothyreosis on cytochrome oxidase and succinic dehydrogenase activities of the rat kidney.", "content": "Effect of hyper- and hypothyreosis on cytochrome oxidase and succinic dehydrogenase activities of the rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359851"}
{"pmid": "4359852", "title": "Induced cellular autophagy in the epithelial cells of seminal vesicle of mice treated with actinomycin D.", "content": "Induced cellular autophagy in the epithelial cells of seminal vesicle of mice treated with actinomycin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359852"}
{"pmid": "4359853", "title": "Morphological aspects of protein synthesis.", "content": "Morphological aspects of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359853"}
{"pmid": "4359854", "title": "Control of protein synthesis in anterior pituitary gland.", "content": "Control of protein synthesis in anterior pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359854"}
{"pmid": "4359856", "title": "Protein synthesis in reproductive tissue. Transactions of the sixth symposium held in Geneva on May 21-23, 1973.", "content": "Protein synthesis in reproductive tissue. Transactions of the sixth symposium held in Geneva on May 21-23, 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359856"}
{"pmid": "4359855", "title": "Oestrogen induced synthesis of a protein in avian liver.", "content": "Oestrogen induced synthesis of a protein in avian liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359855"}
{"pmid": "4359858", "title": "Amebiasis presenting as an acute abdomen.", "content": "Amebiasis presenting as an acute abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359858"}
{"pmid": "4359859", "title": "Milk-rejection sign of breast cancer.", "content": "Milk-rejection sign of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359859"}
{"pmid": "4359860", "title": "Galactography in the examination of secretory breasts.", "content": "Galactography in the examination of secretory breasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359860"}
{"pmid": "4359857", "title": "Initiation of free radical reactions and hepatotoxicity in rats poisoned with carbon tetrachloride or bromotrichloromethane.", "content": "Initiation of free radical reactions and hepatotoxicity in rats poisoned with carbon tetrachloride or bromotrichloromethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359857"}
{"pmid": "4359864", "title": "Effects of various mitogens on the phospholipid metabolism of human peripheral lymphocytes.", "content": "Effects of various mitogens on the phospholipid metabolism of human peripheral lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359864"}
{"pmid": "4359865", "title": "On the metabolic conversion of human plasma very low density lipoprotein to low density lipoprotein.", "content": "On the metabolic conversion of human plasma very low density lipoprotein to low density lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359865"}
{"pmid": "4359867", "title": "Metabolism of rat plasma very low density lipoprotein. II. Fate in circulation of apoprotein subunits.", "content": "Metabolism of rat plasma very low density lipoprotein. II. Fate in circulation of apoprotein subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359867"}
{"pmid": "4359866", "title": "Metabolism of rat plasma very low density lipoprotein. I. Fate in circulation of the whole lipoprotein.", "content": "Metabolism of rat plasma very low density lipoprotein. I. Fate in circulation of the whole lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359866"}
{"pmid": "4359868", "title": "Identification of lipoprotein families in familial lecithin: cholesterol acyltransferase deficiency.", "content": "Identification of lipoprotein families in familial lecithin: cholesterol acyltransferase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359868"}
{"pmid": "4359870", "title": "The effect of K+ and pH on protein-dodecylsulphate complexes.", "content": "The effect of K+ and pH on protein-dodecylsulphate complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359870"}
{"pmid": "4359869", "title": "Comparative studies on adrenal iron-sulfur protein and its selenium derivatives by electron nuclear double resonance.", "content": "Comparative studies on adrenal iron-sulfur protein and its selenium derivatives by electron nuclear double resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359869"}
{"pmid": "4359871", "title": "The intracellular distribution of the radiocopper derived from ceruloplasmin and from albumin.", "content": "The intracellular distribution of the radiocopper derived from ceruloplasmin and from albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359871"}
{"pmid": "4359872", "title": "Application of the fluorescent antibody technique to the diagnosis of avian encephalomyelitis.", "content": "Application of the fluorescent antibody technique to the diagnosis of avian encephalomyelitis. A direct fluorescent antibody test was applied to the diagnosis of avian encephalomyeltis in experimental chicks and in chicks from three natural outbreaks of the disease. Intracerebrally inoculated chicks exhibited maximum fluorescence in brain tissue during the early clinical stages of the disease and similar observations were made on natural cases. Best fluorescence was obtained with frozen sections of cerebellum and pancreas from chicks approximately three weeks of age, but after four weeks of age it was not possible to diagnose the naturally-occurring (field) disease by this method. In these cases a diagnosis of avian encephalomyelitis was confirmed by the application of the fluorescent technique to the brains of either (a) chicks which had hatched from eggs inoculated with brain homogenates from the field cases or (b) hatched chicks which had been inoculated with the homogenates by the intracerebral route.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359872"}
{"pmid": "4359873", "title": "Experimental alkylmercurial poisoning in swine. Lesions in the peripheral and central nervous systems.", "content": "Experimental alkylmercurial poisoning in swine. Lesions in the peripheral and central nervous systems. The effects of alkylmercurial poisoning were studied in 16 pigs poisoned with daily oral doses of a fungicide containing methylmercury 2, 3-dihydroxy propyl mercaptide and methylmercury acetate. Clinical signs included weakness, wobbling gait, blindness, recumbency and death. Microscopic studies of the peripheral nervous system revealed Wallerian degeneration in sensory fibers and neuronal degeneration in dorsal root ganglia. In the central nervous system, there were neuronal degeneration of ischemic type, glial degeneration, gliosis and necrosis of the media of meningeal arterioles. The last mentioned lesion was not extensive.The sequential development o lesions and the absence of segmental demyelination suggest that the primary lesion in the peripheral nervous system was neuronal-axonal degeneration rather than degeneration of the Schwann cell and myelin sheath.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359873"}
{"pmid": "4359874", "title": "Effects of dietary cholesterol on bile acid synthesis in liver and hepatomas.", "content": "Effects of dietary cholesterol on bile acid synthesis in liver and hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359874"}
{"pmid": "4359875", "title": "Spectrophotometric analysis of cytochromes in rat liver during carcinogenesis.", "content": "Spectrophotometric analysis of cytochromes in rat liver during carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359875"}
{"pmid": "4359876", "title": "Inhibition of purine ribonucleotide and phosphoribosyl pyrophosphate synthesis by 6-cyclopentylthio-9-hydroxymethylpurine and structurally related compounds.", "content": "Inhibition of purine ribonucleotide and phosphoribosyl pyrophosphate synthesis by 6-cyclopentylthio-9-hydroxymethylpurine and structurally related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359876"}
{"pmid": "4359877", "title": "Lack of syncytium formation by a type C virus-producing XC cell line in the mixed culture cytopathogenicity test.", "content": "Lack of syncytium formation by a type C virus-producing XC cell line in the mixed culture cytopathogenicity test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359877"}
{"pmid": "4359878", "title": "An electron microscopic study of spontaneous and experimentally induced leukemia in ICRC mice.", "content": "An electron microscopic study of spontaneous and experimentally induced leukemia in ICRC mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359878"}
{"pmid": "4359879", "title": "Prevention of 334C murine virus-induced leukemia by transmission of maternal immunity to offspring.", "content": "Prevention of 334C murine virus-induced leukemia by transmission of maternal immunity to offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359879"}
{"pmid": "4359882", "title": "Effect of a carcinogenic oral dose of 7, 12-dimethylbenz(a)anthracene on receptor binding of estradiol-17 beta in uterus and mammary tissue throughout lactation in the rat.", "content": "Effect of a carcinogenic oral dose of 7, 12-dimethylbenz(a)anthracene on receptor binding of estradiol-17 beta in uterus and mammary tissue throughout lactation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359882"}
{"pmid": "4359881", "title": "Effect of aminonucleoside on serum stimulation of nonhistone nuclear protein and DNA synthesis in normal and SV40-transformed human fibroblats.", "content": "Effect of aminonucleoside on serum stimulation of nonhistone nuclear protein and DNA synthesis in normal and SV40-transformed human fibroblats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359881"}
{"pmid": "4359880", "title": "Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine.", "content": "Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359880"}
{"pmid": "4359883", "title": "Glucocorticoid receptors and mechanism of resistance in the cortisol-sensitive and -resistant lines of lymphosarcoma P1798.", "content": "Glucocorticoid receptors and mechanism of resistance in the cortisol-sensitive and -resistant lines of lymphosarcoma P1798.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359883"}
{"pmid": "4359884", "title": "Imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in behavior of L-ornithine:2-oxoacid aminotransferase (ornithine transaminase, EC 2.6.1.13).", "content": "Imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in behavior of L-ornithine:2-oxoacid aminotransferase (ornithine transaminase, EC 2.6.1.13).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359884"}
{"pmid": "4359885", "title": "Identity of the paramagnetic element found in increased concentrations in plasma of cancer patients and its relationship to other pathological processes.", "content": "Identity of the paramagnetic element found in increased concentrations in plasma of cancer patients and its relationship to other pathological processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359885"}
{"pmid": "4359886", "title": "Transfer RNA base composition studies in Morris hepatomas and rat liver.", "content": "Transfer RNA base composition studies in Morris hepatomas and rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359886"}
{"pmid": "4359888", "title": "On the pathological modification of serum high density lipoproteins in liver diseases. An alteration in the binding mode of indocyanine-green with human serum proteins.", "content": "On the pathological modification of serum high density lipoproteins in liver diseases. An alteration in the binding mode of indocyanine-green with human serum proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359888"}
{"pmid": "4359889", "title": "The inorganic pyrophosphatase activity associated with the forms of alkaline phosphatases isolated from human serum.", "content": "The inorganic pyrophosphatase activity associated with the forms of alkaline phosphatases isolated from human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359889"}
{"pmid": "4359890", "title": "Cyclic AMP stimulated phosphorylation of erythrocyte membranes from cystic fibrosis and control subjects.", "content": "Cyclic AMP stimulated phosphorylation of erythrocyte membranes from cystic fibrosis and control subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359890"}
{"pmid": "4359891", "title": "5'nucleotidase: recent advances in cell biology, methodology and clinical significance.", "content": "5'nucleotidase: recent advances in cell biology, methodology and clinical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359891"}
{"pmid": "4359894", "title": "Computer extraction of an ultradian cycle in sleep from manually scored sleep stages.", "content": "Computer extraction of an ultradian cycle in sleep from manually scored sleep stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359894"}
{"pmid": "4359892", "title": "Screening for primary liver cancer. The relationship between the time of appearance of alpha-foetoprotein in the serum and clinical symptoms in nine cases.", "content": "Screening for primary liver cancer. The relationship between the time of appearance of alpha-foetoprotein in the serum and clinical symptoms in nine cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359892"}
{"pmid": "4359895", "title": "Glomus tumor. A case report.", "content": "Glomus tumor. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359895"}
{"pmid": "4359896", "title": "Bovine enteroviruses in the calf: an attempt at serologic, biologic, and pathologic classification.", "content": "Bovine enteroviruses in the calf: an attempt at serologic, biologic, and pathologic classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359896"}
{"pmid": "4359897", "title": "Preslaughter treatment affecting intramuscular and plasma lipids. I. Effect of ACTH in rabbits.", "content": "Preslaughter treatment affecting intramuscular and plasma lipids. I. Effect of ACTH in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359897"}
{"pmid": "4359900", "title": "Genetic manipulation of motor output in shaker mutants of Drosophila.", "content": "Genetic manipulation of motor output in shaker mutants of Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359900"}
{"pmid": "4359898", "title": "The derivation of plasma-free fatty acids from dietary neutral fat in man.", "content": "The derivation of plasma-free fatty acids from dietary neutral fat in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359898"}
{"pmid": "4359899", "title": "Leroy's l-cell disease: markedly increased activity of plasma acid hydrolases.", "content": "Leroy's l-cell disease: markedly increased activity of plasma acid hydrolases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359899"}
{"pmid": "4359901", "title": "Some physiological and biochemical features of striated muscles reinnervated by preganglionic sympathetic fibers.", "content": "Some physiological and biochemical features of striated muscles reinnervated by preganglionic sympathetic fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359901"}
{"pmid": "4359902", "title": "Identity of \"dumbbell\" profiles in synaptosomal fractions from rat brain.", "content": "Identity of \"dumbbell\" profiles in synaptosomal fractions from rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359902"}
{"pmid": "4359905", "title": "Changes in the excitability of Renshaw cells due to orthodromic tetanic stimuli.", "content": "Changes in the excitability of Renshaw cells due to orthodromic tetanic stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359905"}
{"pmid": "4359906", "title": "T-shaped cells of dorsal ganglia can influence the pattern of afferent discharge.", "content": "T-shaped cells of dorsal ganglia can influence the pattern of afferent discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359906"}
{"pmid": "4359907", "title": "RNA viruses: the age of innocence ends.", "content": "RNA viruses: the age of innocence ends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359907"}
{"pmid": "4359908", "title": "Visna virus infection of American lambs.", "content": "Visna virus infection of American lambs. Random-bred fetal and 4-week-old American lambs, inoculated intracerebrally with visna virus, developed a persistent infection in the brain and sometimes in the lung. The pathologic changes present in these lambs were similar to the early lesions of visna in Icelandic sheep, thus providing a possible model for the study of virus-induced demyelinating disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359908"}
{"pmid": "4359910", "title": "Congenital infections due to reovirus type 3 in hamsters.", "content": "Congenital infections due to reovirus type 3 in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359910"}
{"pmid": "4359903", "title": "Future directions for automated analysis.", "content": "Future directions for automated analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359903"}
{"pmid": "4359911", "title": "Effect of furosemide administration and upright position on plasma renin activity and angiotensin II in hypertension.", "content": "Effect of furosemide administration and upright position on plasma renin activity and angiotensin II in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359911"}
{"pmid": "4359917", "title": "Primary linitis plastica of the rectum. Report of two cases.", "content": "Primary linitis plastica of the rectum. Report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359917"}
{"pmid": "4359918", "title": "The structure of novel C35 pentacyclic terpenes from Acetobacter xylinum.", "content": "The structure of novel C35 pentacyclic terpenes from Acetobacter xylinum. A novel C(35) terpene and its monounsaturated analogue were isolated from cultures of Acetobacter xylinum, together with traces of their C(36) homologues. These substances were found to be hopane derivatives substituted by a five-carbon chain bearing four vicinal hydroxyl groups. For the parent hydrocarbon the term bacteriohopane is proposed. The elucidation of the structures utilized high-resolution mass spectrometry of the terpenes, degradation to C(32) hydrocarbons and detailed mass-spectrometric comparison of these with C(32) hydrocarbons synthesized from known pentacyclic triterpenes. High-resolution mass-spectral data of the terpenes are presented. N.m.r. data are in agreement with the proposed structures, which are further supported by the isolation from the same organism of 22-hydroxyhopane and derivative hopene(s).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359918"}
{"pmid": "4359919", "title": "The nature of the electrophoretically separable multiple forms of rat liver monoamine oxidase.", "content": "The nature of the electrophoretically separable multiple forms of rat liver monoamine oxidase. 1. Treatment of a partly purified preparation of rat liver monoamine oxidase with the chaotropic agent sodium perchlorate caused the enzyme to migrate as a single band of activity of polyacrylamide-gel electrophoresis, whereas the untreated enzyme separated into a number of bands. 2. Treatment with the chaotropic agent caused no loss of enzyme activity towards benzylamine, dopamine or tyramine. 3. The activities of the untreated preparation towards different substrates were inhibited to different extents by heat treatment and by some inhibitors. No such differences could be detected after the enzyme preparation had been treated with sodium perchlorate. 4. Lipid material, which could be separated by gel filtration, was liberated from the enzyme preparation by sodium perchlorate treatment. 5. The molecular weight of the treated enzyme was found to be 380000+/-38000. 6. Perchlorate treatment altered the solubility of the enzyme. 7. A continuous assay method for monoamine oxidase is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359919"}
{"pmid": "4359920", "title": "The structure of a beta-(1 leads to 3)-D-glucan from yeast cell walls.", "content": "The structure of a beta-(1 leads to 3)-D-glucan from yeast cell walls. Yeast glucan as normally prepared by various treatments of yeast (Saccharomyces cerevisiae) cell walls to remove mannan and glycogen is still heterogeneous. The major component (about 85%) is a branched beta-(1-->3)-glucan of high molecular weight (about 240000) containing 3% of beta-(1-->6)-glucosidic interchain linkages. The minor component is a branched beta-(1-->6)-glucan. A comparison of our results with those of other workers suggests that different glucan preparations may differ in the degree of heterogeneity and that the major beta-(1-->3)-glucan component may vary considerably in degree of branching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359920"}
{"pmid": "4359923", "title": "The kinetics of the interconversion of intermediates of the reaction of pig muscle lactate dehydrogenase with oxidized nicotinamide-adenine dinucleotide and lactate.", "content": "The kinetics of the interconversion of intermediates of the reaction of pig muscle lactate dehydrogenase with oxidized nicotinamide-adenine dinucleotide and lactate. Oxamate competes with pyruvate for the substrate binding site on the E(NADH) complex of pig skeletal muscle lactate dehydrogenase. When this enzyme was mixed with saturating concentrations of NAD(+) and lactate in a stopped-flow rapid-reaction spectrophotometer there was no transient accumulation of enzyme complexes with the reduced nucleotide. The steady-state rate of formation of free NADH was reached within the dead-time of the instrument (3ms). When oxamate was added to inhibit the steady state and to uncouple the equilibration: [Formula: see text] through the rapid formation of E(NADH) (Oxamate), the rate of formation of E(NADH) could be measured by observation of the first turnover. This pH-dependent transient is controlled by the rate of dissociation of pyruvate and the fraction of the enzyme in the form E(NADH) (Pyruvate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359923"}
{"pmid": "4359921", "title": "The purification and regulatory properties of alpha-oxoglutarate dehydrogenase from Acineobacter iwoffi.", "content": "The purification and regulatory properties of alpha-oxoglutarate dehydrogenase from Acineobacter iwoffi. The alpha-oxoglutarate dehydrogenase multienzyme complex was purified from Acinetobacter lwoffi to a high degree of homogeneity as shown by gel electrophoresis and analytical ultracentrifugation. Sedimentation-velocity analyses gave s(20,w) values which increased with increasing protein concentration, suggesting dissociation of the complex in dilute solution. The maximum s(20,w) value thereby obtained and the value determined by active enzyme centrifugation were both in the range 28-29S. Electron micrographs of the complex indicated a molecular diameter of 20-22nm (200-220A). The overall activity of the complex was inhibited by NADH, and kinetic studies indicated sites of action on the first and third enzyme components. AMP and ADP relieved this inhibition and also stimulated enzyme activity. Assays specific for the first enzyme component showed this to be the site of action of the adenylates. The activity of the complex varied with energy charge in a manner consistent with its role in energy metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359921"}
{"pmid": "4359922", "title": "Evidence that chick tendon procollagen must be denatured to serve as substrate for proline hydroxylase.", "content": "Evidence that chick tendon procollagen must be denatured to serve as substrate for proline hydroxylase. The ability of chick-embryo proline hydroxylase to hydroxylate [(14)C]proline-labelled procollagen was investigated between 23 degrees and 37 degrees C. The amount of hydroxy[(14)C]proline that could be formed increased sharply between 26 degrees and 30 degrees C. This corresponded to the temperature interval in which the [(14)C]procollagen substrate was thermally denatured, and the results therefore indicate that only denatured molecules can be hydroxylated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359922"}
{"pmid": "4359924", "title": "Editorial: New assays for old.", "content": "Editorial: New assays for old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359924"}
{"pmid": "4359925", "title": "Nervous system involvement in ankylosing spondylitis.", "content": "Nervous system involvement in ankylosing spondylitis. In a review of 45 patients with ankylosing spondylitis 10 had neurological symptoms and signs and three of them had two separate neuropathological disorders. The neurological profiles fell into five main categories-multiple sclerosis, the cauda equina syndrome, focal epilepsy, vertebrobasilar insufficiency, and peripheral nerve lesions. An association between ankylosing spondylitis and multiple sclerosis is suggested, possibly due to an immunological defect or to one being a complication of the other.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359925"}
{"pmid": "4359926", "title": "Changes in antigenic nature of lymphocytes caused by common viruses.", "content": "Changes in antigenic nature of lymphocytes caused by common viruses. Healthy human lymphocytes were incubated in the presence of influenza A2/Singapore/57, herpes simplex type 1, or adenovirus type 2. After two days the cultures were inactivated by irradiation. Fresh lymphocytes taken from the same donor were then found to react to the virus-treated cells in short-term cultures. We suggest that this reactivity is due to a change in the surface characteristics of the lymphocytes brought about by the presence of the virus. This may account for anomalous reactions in mixed lymphocyte cultures, and a similar effect in vivo might cause accelerated graft rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359926"}
{"pmid": "4359928", "title": "Repression, interference, and field dependence as factors in dream forgetting.", "content": "Repression, interference, and field dependence as factors in dream forgetting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359928"}
{"pmid": "4359929", "title": "Determination of iron in low-iron diets by colorimetric and atomic absorption procedures.", "content": "Determination of iron in low-iron diets by colorimetric and atomic absorption procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359929"}
{"pmid": "4359930", "title": "Gas-liquid chromatographic method for the determination of dimethoate and dimethoxon residues in plant and animal tissues, milk, and eggs.", "content": "Gas-liquid chromatographic method for the determination of dimethoate and dimethoxon residues in plant and animal tissues, milk, and eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359930"}
{"pmid": "4359931", "title": "The rapid chromatographic analysis of the free nucleotides from rat brain.", "content": "The rapid chromatographic analysis of the free nucleotides from rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359931"}
{"pmid": "4359932", "title": "Simple separation of neutral lipid classes with two dimensional thin-layer chromatography.", "content": "Simple separation of neutral lipid classes with two dimensional thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359932"}
{"pmid": "4359934", "title": "The rapid liquid chromatographic analysis of mixtures of 5'-nucleotides and mixtures of flavin nucleotides and 5'-AMP.", "content": "The rapid liquid chromatographic analysis of mixtures of 5'-nucleotides and mixtures of flavin nucleotides and 5'-AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359934"}
{"pmid": "4359933", "title": "Separation of mammalian neutral lipids by chromatography on glass-fiber paper impregnated with silica gel.", "content": "Separation of mammalian neutral lipids by chromatography on glass-fiber paper impregnated with silica gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359933"}
{"pmid": "4359935", "title": "Application of vapor phase chromatography to the quantitative determination of conjugated estrogens in drugs.", "content": "Application of vapor phase chromatography to the quantitative determination of conjugated estrogens in drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359935"}
{"pmid": "4359936", "title": "Reversal of cyclic AMP-mediated intestinal secretion by ethacrynic acid.", "content": "Reversal of cyclic AMP-mediated intestinal secretion by ethacrynic acid. Ethacrynic acid (EA) has been reported to reduce cholera toxin-induced intestinal fluid secretion in the intact animal. We explored the nature of this inhibition in vitro by measuring unidirectional, transmural fluxes of (22)Na and (36)Cl across isolated rabbit ileal mucosa. Under control conditions (short-circuited mucosa bathed in bicarbonate-Ringer), there was net absorption of Na and Cl. Theophylline (10 mM), cyclic AMP (5 mM), and cholera toxin (added in vivo) abolished net Na flux and produced net Cl secretion. In the presence of either theophylline or cAMP, addition of 0.1 mM EA to the serosal bathing solution abolished net Cl secretion and restored net Na absorption. Cholera toxin-treated mucosa was exposed to 0.05 and 1.0 mM EA. The lower concentration restored net Na absorption but did not significantly reduce Cl secretion. The higher concentration abolished net transport of both Na and Cl. Short-circuit current and Na flux measurements in the presence and absence of glucose indicated that 0.1 mM EA does not inhibit glucose-coupled Na transport. Short-circuit current measurements in the presence of 1.0 mM EA suggested that even this concentration of EA does not inhibit glucose-coupled Na transport. Thus EA appears to specifically inhibit Cl (or NaCl) secretion without inhibiting the absorptive Na \"pump.\" The anti-secretory effect of 0.1 mM EA does not appear to result from inhibition of adenylate cyclase since secretion stimulated by addition of 5 mM cAMP was abolished. Furthermore, 0.1 mM EA did not significantly reduce theophylline-augmented and cholera toxin-augmented cAMP levels in ileal mucosa. We conclude that EA interacts specifically with the active Cl (or NaCl) secretory mechanism of the small intestine at a step beyond generation of cAMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359936"}
{"pmid": "4359937", "title": "Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes.", "content": "Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. The plasma pyridoxal-5'-phosphate (PLP) level of alcoholic subjects has been compared with that of non-alcoholic individuals in order to ascertain the incidence of abnormal vitamin B(6) metabolism in chronic alcohol abuse. 66 alcoholic subjects were selected on the basis that they did not exhibit abnormal liver function tests and hematologic findings. 35 of them had plasma PLP concentrations less than 5 ng/ml, the lowest value encountered in 94 control subjects, indicating a high incidence of deranged PLP metabolism in alcoholic patients even when hepatic and hematologic abnormalities are absent. The biochemical basis for the altered PLP metabolism in chronic alcohol abuse was examined. Low plasma PLP levels in alcoholics were not accompanied by decreased pyridoxal kinase and pyridoxine phosphate oxidase activities in erythrocytes. Further studies with erythrocytes demonstrated that the cellular content of PLP is determined not only by the activities of these PLP-synthesizing enzymes but also by the activity of a phosphate-sensitive, membrane-associated, neutral phosphatase, which hydrolyzes phosphorylated B(6) compounds.Acetaldehyde, but not ethanol, impaired the net formation of PLP from pyridoxal, pyridoxine, and pyridoxine phosphate by erythrocytes. However, when the B(6)-phosphate phosphatase activity was inhibited by 80 mM phosphate, this effect of acetaldehyde was abolished. By the use of broken cell preparations, it was possible to demonstrate directly that the action of acetaldehyde is mediated by the phosphatase, resulting in an acceleration of the degradation of the phosphorylated B(6) compounds in erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359937"}
{"pmid": "4359938", "title": "Direct inhibitory effect of hypercalcemia on renal actions of parathyroid hormone.", "content": "Direct inhibitory effect of hypercalcemia on renal actions of parathyroid hormone. The effects of calcium on the renal actions of parathyroid hormone (PTH) were studied in vivo and in vitro. In parathyroidectomized rats, variable levels of blood calcium concentration were induced by intravenous infusion of calcium. The renal responses to the injected PTH, i.e. phosphate and cyclic AMP excretion, were compared in these animals. After PTH injection, the increases of both phosphate and cyclic AMP excretion were less in the calcium-infused animals than in the control group without calcium infusion. There was an inverse correlation between the renal responses to PTH and plasma calcium concentration of 4.2-13.5 mg/100 ml. But calcium had no effect on phosphate excretion induced by infusion of dibutyryl cyclic AMP. In the in vitro experiments, the increase of cyclic AMP concentration in response to PTH was less in renal cortical slices taken from the calcium-infused animals than in ones from the control group without calcium infusion. Calcium also inhibited the activation of renal cortical adenylate cyclase in response to PTH, but calcium had no effect on phosphodiesterase. The data indicate that calcium directly inhibits renal actions of PTH both in vivo and in vitro. Such inhibitory mechanism is probably at or before the step of PTH-dependent cyclic AMP generation in the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359938"}
{"pmid": "4359940", "title": "Effects of ethacrynic acid on the isolated collecting tubule.", "content": "Effects of ethacrynic acid on the isolated collecting tubule. Effects of the diuretic ethacrynic acid on osmotic water permeability were investigated in the isolated perfused collecting tubule of the rabbit kidney. The base-line water permeability of the collecting tubule was not affected when the drug (10(-4)M) alone was added to the bathing medium. Vasopressin alone in the bathing medium (2, 5 muU/ml) elicited a significant increase in osmotic water absorption. With vasopressin kept in the bathing medium, the addition of 10(-5)M ethacrynic acid depressed the hydro-osmotic effect of vasopressin by 50%. This inhibitory effect of low concentrations of ethacrynic acid could be surmounted by high, supramaximal dosage levels of vasopressin. When 10(-4)M ethacrynic acid was added to the bathing medium before vasopressin, the hydro-osmotic effect of vasopressin and the diuretic in combination was insignificant.Dibutyryl adenosine 3'5'-monophosphate (10(-4)-10(-2)M) alone in the bathing medium significantly increased baseline osmotic water flow, mimicing the effect of antidiuretic hormone. When ethacrynic acid was added together with the nucleotide, the permeability remained at the same high level. Theophylline, like the nucleotide and vasopressin, produced a significant hydro-osmotic effect. The magnitude of this response was not affected by further addition of ethacrynic acid (10(-4)M). It was concluded that ethacrynic acid is an antagonist of antidiuretic hormone. The antagonism probably occurs at the level of the receptor site of the hormone on the peritubular membrane. Antagonism to circulating antidiuretic hormone may therefore be one of the factors involved in the loss of renal concentrating ability brought about by ethacrynic acid diuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359940"}
{"pmid": "4359939", "title": "Study of the renal tubular interactions of thyrocalcitonin, cyclic adenosine 3',5'-monophosphate, 25-hydroxycholecalciferol, and calcium ion.", "content": "Study of the renal tubular interactions of thyrocalcitonin, cyclic adenosine 3',5'-monophosphate, 25-hydroxycholecalciferol, and calcium ion. Acute clearance studies were performed in thyroparathyroidectomized animals to determine the actions and interactions of thyrocalcitonin (TCT), cyclic adenosine 3'5'-monophosphate (cAMP), 25-hydroxycholecalciferol (25HCC), and calcium ion on the reabsorption of phosphate, calcium, sodium, and potassium by the kidney. The infusion of 25HCC in a dosage of 60 U/h to moderately saline-expanded animals (2.5% body weight) induced a fall in the excretion of all of the ions under study after 90-120 min similar to that observed in previous experiments from this laboratory. Mean decrements in fractional excretion were: phosphate, 42.0% (P < 0.005); calcium, 25.0% (P < 0.005); sodium, 23.4% (P < 0.001); and potassium, 14.7% (P < 0.005). The superimposition of either porcine or salmon TCT (1-100 MRC U/h for 2 h) resulted in no further alterations in electrolyte excretion. However, the infusion of TCT during steady-state saline expansion, before the administration of 25HCC, obviated the renal transport effects of the vitamin D metabolite. Both in the latter studies, as well as those in which similar doses of TCT were given to hydropenic animals, the hormone itself failed to induce any consistent alteration in electrolyte excretion. Cyclic AMP (50 mg/h) caused an increase in the excretion of phosphate, sodium, and potassium and no change in calcium excretion. Like TCT, the nucleotide blocked the action of 25HCC on the kidney. Raising the mean level of serum ultrafilterable calcium to 3.02+/-0.25 mEq/liter from 1.62+/-0.17 mEq/liter likewise prevented enhanced ionic reabsorption due to 25HCC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359939"}
{"pmid": "4359942", "title": "Ultrastructure of taper hepatoma ascites cells.", "content": "Ultrastructure of taper hepatoma ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359942"}
{"pmid": "4359941", "title": "Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic AMP accumulation. Evidence against an essential role for prostaglandins in the action of toxin.", "content": "Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic AMP accumulation. Evidence against an essential role for prostaglandins in the action of toxin. Both cholera enterotoxin and certain prostaglandins have been shown to stimulate intestinal fluid secretion in vivo, to cause ion flux changes in vitro similar to those caused by addition of cyclic 3',5'-adenosine monophosphate (cyclic AMP), and to activate intestinal mucosal adenyl cyclase. It has been suggested that the effects of the enterotoxin on intestinal cyclic AMP metabolism may be indirect, and that locally synthesized prostaglandins may serve as required intermediates for the effects of the enterotoxin in activating intestinal mucosal adenyl cyclase. In order to clarify certain aspects of the mechanisms by which these two agents alter intestinal mucosal cyclic AMP metabolism and ion transport, their effects on cyclic AMP accumulation in rabbit ileal mucosa were examined in vitro. Addition of 5 mug per ml (75 mug per 150 mg mucosa) of purified cholera enterotoxin produced a peak increase in cyclic AMP level in 3 h but there was a time delay of at least 30 min before any effect was observed. Inhibition of cyclic nucleotide phosphodiesterase with theophylline failed to reduce this time delay. In contrast, addition of prostaglandin E(1) (PGE(1)) increased the cyclic AMP level rapidly, a peak effect being observed in 2 min. The time of the peak prostaglandin-induced changes in cyclic AMP level and short-circuit current correlated closely. A maximal increment in cyclic AMP level was achieved with 5 x 10(-5) M PGE(1). When 10(-4) M PGE(1) was added to mucosa already maximally stimulated with cholera toxin, the resulting cyclic AMP level was equal to the sum of the levels reached when each agent was added alone. Furthermore, the effects of the enterotoxin on mucosal cyclic AMP levels were not influenced by indomethacin under conditions where mucosal prostaglandins synthesis was inhibited. The results suggest that endogenous prostaglandins do not provide an essential link in the activation of intestinal mucosal adenyl cyclase by cholera enterotoxin. The present study also indicates that the effect of cholera enterotoxin on intestinal mucosal cyclic AMP metabolism involves a definite time delay which is not due to cyclic nucleotide phosphodiesterase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359941"}
{"pmid": "4359943", "title": "Effects of oestrogen antagonists on mitosis and (3H)oestradiol binding in the mouse uterus.", "content": "Effects of oestrogen antagonists on mitosis and (3H)oestradiol binding in the mouse uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359943"}
{"pmid": "4359944", "title": "Inhibition by dexamethasone of adrenocorticotrophin and cortisol release induced by intravenous infusion of ATP and dibutyryl cyclic AMP in piglets.", "content": "Inhibition by dexamethasone of adrenocorticotrophin and cortisol release induced by intravenous infusion of ATP and dibutyryl cyclic AMP in piglets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359944"}
{"pmid": "4359945", "title": "The mechanism of androgen uptake and concentration by rat ventral prostate in organ culture.", "content": "The mechanism of androgen uptake and concentration by rat ventral prostate in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359945"}
{"pmid": "4359947", "title": "Genetic and physiological properties of temperature-sensitive mutants of Cocal virus.", "content": "Genetic and physiological properties of temperature-sensitive mutants of Cocal virus. Temperature-sensitive (ts) mutants of Cocal virus (VSV Cocal) were isolated after treatment with the base analogue mutagen, 5-fluorouracil. These mutants could be classified into four mutually complementing groups. Weak complementation was detected between certain pairs of VSV Cocal ts mutants and ts mutants of vesicular stomatitis virus (VSV) Indiana, but no complementation was observed with ts mutants of VSV New Jersey. Two complementing ts mutants of Chandipura virus, an unrelated rhabdovirus, did not complement any VSV mutant, Thus, ability to complement in the VSV group appears to be correlated with serological relationships. The RNA and protein-synthesizing capacities of these ts mutants have been determined, and it is possible to establish a correspondence between the VSV Cocal and the VSV Indiana complementation groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359947"}
{"pmid": "4359946", "title": "Unwinding of parental strands during simian virus 40 DNA replication.", "content": "Unwinding of parental strands during simian virus 40 DNA replication. Pools of young (less than 60% replicated) and mature (60-90% replicated) replicating molecules of simian virus 40 (SV40) DNA have been treated at pH 12.2 in order to dissociate growing chains from the parental strands. The molecules are neutralized so that the parental strands can reassociate and they have then been isolated. They are covalently closed structures which sediment rapidly in alkaline sucrose gradients; however, the sedimentation rates are less than the sedimentation rate of SV40 DNA I. Isopycnic banding in CsCl-ethidium bromide and sedimentation velocity studies in the presence of various amounts of ethidium bromide indicate that these structures contain negative superhelical turns and several-fold-higher superhelix densities than SV40 DNA I (the covalently closed DNA molecule). These structures are those that would be predicted if nicking, unwinding, and sealing of the parental strands occurred as replication proceeded. These experiments provide a direct demonstration that there is a progressive decrease in the topological winding number which accompanies SV40 DNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359946"}
{"pmid": "4359948", "title": "Phosphorylation of simian virus 40 proteins in a cell-free system.", "content": "Phosphorylation of simian virus 40 proteins in a cell-free system. We have shown previously that all the structural proteins of simian virus 40 (SV40) are phosphoproteins. Virus phosphorylated in vivo could be further phosphorylated with exogenous cellular protein kinases in a cell-free system containing gamma-(32)P-ATP as phosphate donor. In intact infectious virus only polypeptides 1 and 2 (mol wt 49,000 and 40,800, respectively) were further phosphorylated in vitro. However, when infectious SV40 was partially disrupted, treated with nucleases, and then phosphorylated in vitro, all five structural polypeptides accepted additional phosphate groups. Similarly, all polypeptides of intact empty capsids, derived from infected cells, were further phosphorylated in vitro. Phosphorylation of empty capsids and infectious SV40 in vitro was enhanced from 4- to 11-fold after prior treatment of virus with alkali. The phosphate group was linked only to serine residues of the viral polypeptides phosphorylated both in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359948"}
{"pmid": "4359950", "title": "Integrated state of oncornavirus DNA in normal chicken cells and in cells transformed by avian myeloblastosis virus.", "content": "Integrated state of oncornavirus DNA in normal chicken cells and in cells transformed by avian myeloblastosis virus. The covalent linkage of oncornavirus-specific DNA to chicken DNA was investigated in normal chicken embryo fibroblasts (CEF) and in virus-producing leukemic cells transformed by avian myeloblastosis virus (AMV). The virus-specific sequences present in cellular DNA fractionated by different methods were detected by DNA-RNA hybridization by using 70S AMV RNA as a probe. In CEF and in leukemic cells, the viral DNA appeared to be present only in the nucleus. After cesium chloride-ethidium bromide density equilibrium sedimentation, the viral DNA was present as linear, double-stranded molecules not separable from linear chicken DNA. After extraction by the Hirt procedure, the viral DNA precipitated with the high-molecular-weight DNA. After alkaline sucrose velocity sedimentation, the viral DNA cosedimented with the high-molecular-weight cellular DNA. The results indicate that in both types of cells studied, the oncornavirus-specific DNA sequences were linked by alkali stable bonds to nuclear cellular DNA of high molecular weight and did not appear to be present in free form of any size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359950"}
{"pmid": "4359949", "title": "Partial transcription of murine type C viral genomes in BALB c cell lines.", "content": "Partial transcription of murine type C viral genomes in BALB c cell lines. The mouse cell line, BALB/c 3T3, and its derivatives transformed either spontaneously or by treatment with a variety of external agents, were analyzed for cytoplasmic RNA complementary to DNA products prepared from the Kirsten strain of murine sarcoma-leukemia virus, and from an endogenous type C virus of BALB/c 3T3. Although none of these cell lines spontaneously releases complete type C virions, they all contain RNA which is partially homologous to a portion of the 35S RNA isolated from these viruses. The parental cell line, BALB/c 3T3, contains a low level of viral-related RNA, and there is an increased amount of this RNA in some of the transformed cells. The RNA detected represents only a fraction of the viral RNA found in virus-producing cells. The formation of RNA:DNA hybrids was detected by equilibrium centrifugation in Cs(2)SO(4) density gradients and by analysis with a single-strand-specific nuclease from Aspergillus oryzae. Viral DNA products prepared either from an endogenous reaction with whole virus in the presence of actinomycin D or from purified 70S viral RNA as template using avian myeloblastosis virus DNA polymerase yield comparable data. In addition, all of the BALB/c lines examined produce detectable levels of murine type C virus group-specific antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359949"}
{"pmid": "4359951", "title": "Reassortment of simian virus 40 DNA during serial undiluted passage.", "content": "Reassortment of simian virus 40 DNA during serial undiluted passage. Alterations occur in the supercoiled form of viral DNA after the serial undiluted passaging of simian virus (SV) 40. We have identified a portion of the viral genome which is amplified during this process. These SV40 DNA sequences represent about 30% of the viral genetic information and are present in a reiterated form in twisted circular molecules prepared from purified virions. In addition, reiterated and unique green monkey DNA sequences are incorporated into supercoiled viral DNA. The cellular DNA appears to be inserted at numerous locations in the DNA I molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359951"}
{"pmid": "4359952", "title": "Separation of Herpes simplex virus-induced antigens by Concanavalin A affinity chromatography.", "content": "Separation of Herpes simplex virus-induced antigens by Concanavalin A affinity chromatography. Biologically active herpes simplex virus (HSV)-induced antigens were selectively removed from extracts of infected BHK cells by affinity chromatography by utilizing an insoluble form of concanavalin A (Con A). Soluble extracts of (3)H-glucosamine-labeled, HSV-infected cells were absorbed to a Con A column. Bound material was eluted with alpha-methyl-d-mannoside (alphaMM) and NaCl. The specific activity of the eluted glycoproteins increased by 10-fold. Two broad groups of viral-induced antigens were isolated from Con A. Group I includes two antigens which bind to Con A by a specific mechanism because the antigens are dissociated by alphaMM. Group II contains three antigens which bind to Con A but apparently by a nonspecific or electrolytic mechanism. One antigen in group I was identified as the glycoprotein antigen, CP-1, described previously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359952"}
{"pmid": "4359954", "title": "Comparison of in vitro and cell-mediated alteration of a human Rhinovirus and its inhibition by sodium dodecyl sulfate.", "content": "Comparison of in vitro and cell-mediated alteration of a human Rhinovirus and its inhibition by sodium dodecyl sulfate. After human rhinovirus type 2 (HRV-2) attaches to HeLa cells, two types of subviral particles are formed which closely resemble particles produced in vitro by acid or heat. One type of particle contains RNA whereas the second sediments as an empty capsid and is RNA-deficient. Sodium dodecyl sulfate (SDS) at 10(-4) M inhibits the cell-mediated formation of these particles from HRV-2 virions and the ability of HRV-2 to form plaques, but it does not inhibit the formation of plaques by human rhinovirus 14 (HRV-14). SDS also stabilizes HRV-2 against inactivation by acid or heat to a much greater extent than it does HRV-14. In a similar manner, SDS protects against the acid inactivation of the subpopulation of HRV-2 natural top component particles which attach to virus-specific cellular receptors. This suggests that the loss of native properties of natural top component particles and of virion are related processes. The basis for this alteration and also its role in infection are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359954"}
{"pmid": "4359955", "title": "Polypeptide composition of Influenza B viruses and enzymes associated with the purified virus particles.", "content": "Polypeptide composition of Influenza B viruses and enzymes associated with the purified virus particles. Influenza B/LEE/40, B/Rome/1/67, B/Hong Kong/8/73, and B/Victoria/98926/70 viruses have a similar polypeptide composition as analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis. These viruses are composed of six or seven polypeptides, depending on whether one or two high-molecular-weight polypeptides are resolved, ranging in molecular weights from 27,000 to 90,400. Three of these polypeptides, namely the heavy and light hemagglutinin chains and the neuraminidase, have attached carbohydrate. Highly purified influenza B/LEE/40 and B/Rome/1/67 virus preparations have RNA-dependent RNA polymerase activity equivalent to the incorporation of 100 and 30 pmol, respectively, of (3)H-UMP per mg of virus protein per h at 37 C, which is demonstrated only in detergent-treated virus suspensions. However, no RNA-dependent DNA polymerase enzyme activity was detected in the two viruses although virus suspensions were \"activated\" by heat, alpha-chymotrypsin, and detergents. Other enzymatic activities were associated with purified preparations of influenza B virus and were attributed to minor contamination of virus with host cell enzymes. Thus, nucleoside and deoxynucleoside phosphohydrolase enzymes were active in the absence of detergents and catalyzed the release of 1,200 and 1,800 nmol of P(i) per mg of virus protein in 30 min at 37 C from ATP and dATP substrates. Thin-layer chromatography indicated that the products of the phosphohydrolase enzymes of influenza B/LEE/40 were mainly nucleoside diphosphate and monophosphate. The latter enzymes were tightly bound to influenza B/LEE/40 virus and could not be removed completely by repeated centrifugation, including centrifugation of the virus to equilibrium in density gradients of 25 to 40% (wt/vol) cesium chloride. A low degree of RNase (approximately 0.01 mug% contamination) and phosphatase (10-30 nmol of P(i) released per mg of virus protein per 30 min) activity was detected in some, but not all, influenza B/LEE/40 virus preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359955"}
{"pmid": "4359956", "title": "Studies of nondefective Adenovirus 2-Simian virus 40 hybrid viruses. 8. Association of Simian virus 40 transplantation antigen with a specific region of the early viral genome.", "content": "Studies of nondefective Adenovirus 2-Simian virus 40 hybrid viruses. 8. Association of Simian virus 40 transplantation antigen with a specific region of the early viral genome. Two of the five nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrids induce SV40 transplantation resistance in immunized hamsters. These two hybrids, Ad2(+)ND(2) and Ad2(+)ND(4), contain 32 and 43% of the SV40 genome, respectively. The pattern of induction of SV40 transplantation antigen (TSTA) by the various hybrids differentiates TSTA from both SV40 U and T antigens. Since the SV40 RNA induced by both these hybrids is early SV40 RNA, these findings confirm that TSTA is an early SV40 function. By combining available data on SV40 antigen induction by these hybrids with electron microscopy heteroduplex mapping studies, the DNA segment responsible for the induction of SV40 TSTA can be inferred to lie in the region between 0.17 and 0.43 SV40 units from the site on the SV40 chromosome cleaved by E. coli R(1) restriction endonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359956"}
{"pmid": "4359953", "title": "SP62, a viable mutant of bacteriophage T4D defective in regulation of phage enzyme synthesis.", "content": "SP62, a viable mutant of bacteriophage T4D defective in regulation of phage enzyme synthesis. SP62 is a mutant of bacteriophage T4D that was discovered because it produces fewer phage than the wild type in the presence of 5-fluorodeoxyuridine. In the absence of phage DNA synthesis, SP62 solubilizes host DNA slower than normal; this may explain the sensitivity to 5-fluorodeoxyuridine. In Escherichia coli B at 37 C in the absence of drugs, SP62 makes DNA at a normal rate and the kinetics of appearance of phage are nearly normal. Under the same conditions, SP62 produces T4 lysozyme (gene e) at a normal rate until 20 min, but then produces it at twice the normal rate until at least 60 min. It has long been known that, when T4 DNA synthesis is blocked (DNA(-) state) in an otherwise normal infection, the synthesis of a number of early enzymes continues beyond the shutoff time of about 12 min seen in the DNA(+) state, but still stops at about 20 min. We have termed the 12-min shutoff event S1 and the 20-min shutoff event S2. We show here that, in the DNA(+) state, SP62 makes four early enzymes normally, i.e., S1 occurs. However, in the DNA(-) state (where S1 is missing), SP62 continues to make dCTPase (gene 56), dCMP hydroxymethylase (gene 42), and deoxynucleotide kinase (gene 1) for at least an hour; this results in production of up to 13 times the normal level of dCTPase at 60 min after infection, or 6 times the DNA(-) level. We conclude that SP62 is defective in the second shutoff mechanism, S2, for these three enzymes. In contrast, SP62 causes premature cessation of dTMP synthetase production in the DNA(-) state; the result is a twofold underproduction of dTMP synthetase. Autoradiograms of pulse-labeled proteins separated by slab-gel electrophoresis in the presence of sodium dodecyl sulfate show that a number of other T4 early proteins, including the products of genes 45, 46, and rIIA, are synthesized longer than normal by SP62 in the DNA(-) state. Few late proteins are made in the DNA(-) state, but in autoradiograms examining the DNA(+) state there is little or no effect of the SP62 mutation on the synthesis of T4 late or early proteins. Circumstantial evidence is presented favoring a role for the gene of SP62 in translation of certain mRNAs. At very high temperatures (above 43 C) in the absence of drugs, phage production, but not DNA synthesis, is much reduced in SP62 infections relative to wild-type T4 infections; this temperature sensitivity is greater on E. coli CR63 than on E. coli B. This property has facilitated recognition of the SP62 genotype and aided in complementation testing and genetic mapping. A later publication will provide evidence that SP62 defines a new T4 gene named regA, which maps between genes 43 and 62.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359953"}
{"pmid": "4359957", "title": "Properties of nucleoprotein complexes containing replicating polyoma DNA.", "content": "Properties of nucleoprotein complexes containing replicating polyoma DNA. Short-lived nucleoprotein complexes (r-py complex) containing replicating polyoma DNA were isolated from infected cells after lysis with Triton X-100. The Triton lysing procedure of Green, Miller, and Hendler (1971) releases most complexes containing supercoiled viral DNA (py complex) from nuclei, but liberates only a portion of r-py complexes. r-py Complexes are associated more strongly with nuclear sites but can be extracted by prolonged incubation of nuclei in lysing solution. Complexes containing replicating polyoma DNA appear to be precursors to stable complexes containing supercoiled DNA. Sedimentation and buoyant density studies indicate that protein is bound to both r-py complexes and py complexes at a ratio of protein to DNA of about 1 to 2/1. Both types of complexes sediment as if the viral DNA is more compact than free DNA and both undergo major reversible configurational changes with increased salt concentration. Changes resulting from enzymatic and chemical treatment indicate that there may be two or more protein components in both r-py complex and py complex. One component is digested by Pronase and trypsin while another is resistant to the enzymes but released by deoxycholate. The abundance and similarity in chemical and physical properties of protein bound to all forms of polyoma DNA suggest that part of the protein molecules may serve in a structural capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359957"}
{"pmid": "4359958", "title": "Nucleoprotein complexes containing replicating Simian virus 40 DNA: comparison with polyoma nucleoprotein complexes.", "content": "Nucleoprotein complexes containing replicating Simian virus 40 DNA: comparison with polyoma nucleoprotein complexes. Procedures for isolating nucleoprotein complexes containing replicating polyoma DNA from infected mouse cells were used to prepare short-lived nucleoprotein complexes (r-SV40 complexes) containing replicating simian virus 40 (SV40) DNA from infected monkey cells. Like the polyoma complexes, r-SV40 complexes were only partially released from nuclei by cell lysis but could be extracted from nuclei by prolonged treatment with solutions containing Triton X-100. r-SV40 complexes sedimented faster than complexes containing SV40 supercoiled DNA (SV40 complex) in sucrose gradients, and both types of SV40 nucleoprotein complexes sedimented ahead of polyoma complexes containing supercoiled polyoma DNA (py complex). The sedimentation rates of py complex and SV40 complex were 56 and 61S, respectively, based on the sedimentation rate of the mouse large ribosomal subunit as a marker. r-SV40 complexes sedimented as multiple peaks between 56 and 75S. Sedimentation and buoyant density measurements indicated that protein is bound to all forms of SV40 DNA at about the same ratio of protein to DNA (1-2/1) as was reported for polyoma nucleoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359958"}
{"pmid": "4359959", "title": "Herpes simplex virus and human cytomegalovirus replication in WI-38 cells. I. Sequence of viral replication.", "content": "Herpes simplex virus and human cytomegalovirus replication in WI-38 cells. I. Sequence of viral replication. A comparison, under standardized conditions, of herpes simplex virus (HSV) and human cytomegalovirus (CMV) revealed differences in viral morphology, in the timing of their infectious cycles, and in several morphological events during those cycles. Structural distinctions between the two viruses included the coating of unenveloped cytoplasmic CMV capsids, but not those of HSV, and a variation in the structure of their cores. Since the two cycles were carried out in the same host cell strain under conditions of one-step growth (input multiplicity = 10 PFU/cell), it was possible to construct time scales locating the major events of each cycle. Comparison of the two showed that HSV replicated and released progeny within 8 h postinfection, whereas CMV required 4 days. These results correlated well with those of concurrent plaque assays. Within the longer CMV cycle, most of the major events appeared retarded to a similar degree, and no obvious limiting step in particle production could be identified. Distinctions between the two cycles included the following: condensation of the chromatin in HSV- but not CMV-infected cells; the greater tendency of HSV to produce membrane alterations; and the appearance of cytoplasmic dense bodies in CMV- but not HSV-infected cells. Identification of these differences even under identical conditions of culture and infection strongly implies that they result from intrinsic differences in the nature of the viruses, and are not caused by variations in experimental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359959"}
{"pmid": "4359960", "title": "Properties of noninfectious and transforming viruses released by Murine sarcoma virus-induced hamster tumor cells.", "content": "Properties of noninfectious and transforming viruses released by Murine sarcoma virus-induced hamster tumor cells. The cell culture lines HTG2 and HTG3 were established from a transplantable hamster tumor induced by a murine sarcoma virus (strain Gz-MSV) after 17 and 60 in vivo passages, respectively. The viruses released by these two cell lines markedly differ in morphology, antigenic composition, infectivity, transforming ability, and enzymatic activity. HTG2 virions contained the sarcoma genome but were noninfectious for mouse and hamster cells (S+H-virus). HTG3 virions transformed hamster but not mouse cells. Whereas HTG2 cells and its virus contained murine type C virus gs-1 antigen, all HTG3 clonal lines expressed both murine and hamster type C virus gs-1 antigens. The RNA-dependent DNA polymerase activity of HTG2 virus was very low, whereas that of HTG3 virus was relatively high. HTG2 virions contained electron-lucent centers only. HTG3 virus consisted of the expected mixture of virions with electron-dense and electron-lucent centers. Many broken or incomplete virions were present in both viruses. HTG2 virus is a noninfectious \"defective\" sarcoma virus without detectable helper virus. Data obtained in these experiments suggest that HTG3 virus is a hamster type C virus pseudotype of Gz-MSV (Gz-MSV [HaLV]). The genome of Gz-MSV is capable of antigenic expression in heterologous cells and in the presence of heterologous viruses. Attempts to chemically activate hamster type C virus (HaLV) from HTG2 cells were unsuccessful. The HTG1 cell culture line, established from another Gz-MSV-induced hamster tumor, initially released a virus indistinguishable from the HTG2 virus. After in vitro passage, spontaneous activation of HaLV occurred in HTG1 cells, and the resultant Gz-MSV (HaLV) had properties similar to those of the HTG3 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359960"}
{"pmid": "4359961", "title": "Factors affecting cell fusion induced by Sendai virus.", "content": "Factors affecting cell fusion induced by Sendai virus. Cell fusion mediated by exogenous Sendai virus appears to occur in four temperature-dependent stages. The first two, which include viral adsorption, are pH dependent and can be inhibited by viral antibody. Viral envelope constituents remain detectable on the cell surface during the third stage and disappear only when cell-to-cell fusion supervenes. The relationship of these interactions to possible mechanisms of cell fusion are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359961"}
{"pmid": "4359962", "title": "Induction of cellular DNA synthesis by the nondefective Adenovirus 2-Simian virus 40 hybrid viruses.", "content": "Induction of cellular DNA synthesis by the nondefective Adenovirus 2-Simian virus 40 hybrid viruses. Induction of cellular DNA synthesis by the nondefective adenovirus 2-simian virus 40 hybrid viruses was examined in monkey and hamster cells. It was not possible to discriminate the effects of the hybrid viruses from those of wild-type adenovirus 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359962"}
{"pmid": "4359963", "title": "Denitrification in granular carbon and sand columns.", "content": "Denitrification in granular carbon and sand columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359963"}
{"pmid": "4359965", "title": "Health-services information systems in the United States today.", "content": "Health-services information systems in the United States today.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359965"}
{"pmid": "4359964", "title": "Defective superoxide production by granulocytes from patients with chronic granulomatous disease.", "content": "Defective superoxide production by granulocytes from patients with chronic granulomatous disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359964"}
{"pmid": "4359966", "title": "Letter: Acute hemorrhagic cystitis due to adenovirus Type 11.", "content": "Letter: Acute hemorrhagic cystitis due to adenovirus Type 11.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359966"}
{"pmid": "4359967", "title": "Renal function in pregnancy.", "content": "Renal function in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359967"}
{"pmid": "4359968", "title": "Influence of malignant cells on the healing of colonic anastomoses: experimental observations.", "content": "Influence of malignant cells on the healing of colonic anastomoses: experimental observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359968"}
{"pmid": "4359969", "title": "Generalized eruptive histiocytoma.", "content": "Generalized eruptive histiocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359969"}
{"pmid": "4359972", "title": "Toward a theory of dream recall.", "content": "Toward a theory of dream recall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359972"}
{"pmid": "4359970", "title": "The sodium story: effects of anaesthesia and surgery on intrarenal mechanisms concerned with sodium homeostasis.", "content": "The sodium story: effects of anaesthesia and surgery on intrarenal mechanisms concerned with sodium homeostasis. Enormous progress has been made in the last 10 years toward an understanding of sodium homeostasis by the kidney.  Much of the relevant literature is reviewed.  Anesthesia and surgery are normally accompanied by severe sodium retention.  2 studies which investigated this area are summarized.  Together they demonstrate the importance of the kidney in monitoring an individual's hemodynamic state and adjusting his sodium excretion accordingly.  1 study showed uniform fluid retention following surgery, even in patients receiving high levels of extra fluid.  Water and sodium retention were shown to be responses to different, unrelated mechanisms.  Plasma or extracellular fluid deficits were shown to be unrelated to the amount of retention.  These 2 studies confirmed an earlier hypothesis by de Bono and Mills that changes in renal hemodynamics may be responsible for changes in sodium excretion.  Actually, a number of substances, all with powerful vasoactive properties, have been isolated in the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359970"}
{"pmid": "4359976", "title": "Adrenalectomy for metastatic carcinoma of the breast. Experience in a community hospital.", "content": "Adrenalectomy for metastatic carcinoma of the breast. Experience in a community hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359976"}
{"pmid": "4359978", "title": "1971 Yant Memorial Lecture. Mining: problems and progress in industrial hygiene.", "content": "1971 Yant Memorial Lecture. Mining: problems and progress in industrial hygiene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359978"}
{"pmid": "4359979", "title": "Adenine arabinoside therapy in corneal stromal disease and iritis due to herpes simplex.", "content": "Adenine arabinoside therapy in corneal stromal disease and iritis due to herpes simplex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359979"}
{"pmid": "4359981", "title": "Effect of oestradiol-3,17beta dipropionate on spermatogenesis and lysosomal enzymes in the rat testis.", "content": "Effect of oestradiol-3,17beta dipropionate on spermatogenesis and lysosomal enzymes in the rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359981"}
{"pmid": "4359980", "title": "Inhibition by plant growth retardants of cholesterol biosynthesis in slices of rat liver and hepatoma.", "content": "Inhibition by plant growth retardants of cholesterol biosynthesis in slices of rat liver and hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359980"}
{"pmid": "4359982", "title": "Experience with a short test of pituitary-adrenal function.", "content": "Experience with a short test of pituitary-adrenal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359982"}
{"pmid": "4359983", "title": "A passive haemagglutination test for the demonstration of antibody to infectious bovine rhinotracheitis-infectious pustular vulvovaginitis virus. 2. Studies on antibody incidence and the serological response after infection.", "content": "A passive haemagglutination test for the demonstration of antibody to infectious bovine rhinotracheitis-infectious pustular vulvovaginitis virus. 2. Studies on antibody incidence and the serological response after infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359983"}
{"pmid": "4359985", "title": "Cyclic 3',5'-adenosine monophosphate dependent protein kinase from dog prostate.", "content": "Cyclic 3',5'-adenosine monophosphate dependent protein kinase from dog prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359985"}
{"pmid": "4359986", "title": "Effect of EGTA on protein release and cyclic AMP accumulation in rat parotid gland.", "content": "Effect of EGTA on protein release and cyclic AMP accumulation in rat parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359986"}
{"pmid": "4359988", "title": "Comparative aspects of equine herpesviruses.", "content": "Comparative aspects of equine herpesviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359988"}
{"pmid": "4359989", "title": "Induction of polyoma DNA synthesis by injection into frog-egg cytoplasm.", "content": "Induction of polyoma DNA synthesis by injection into frog-egg cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359989"}
{"pmid": "4359987", "title": "The physiology of prostaglandins.", "content": "The physiology of prostaglandins. This is a review from the literature dealing with the physiology of prostaglandins (PGs).  PGs E and F are biosynthesized from straight chain C-20 fatty acids, arachidonic acid being the precursor of 2 of the series and dihomo-linolenic acid the precursor of the other series.  Availability of certain cofactors during synthesis probably determines which PG is formed.  The amounts of PGs in the tissues are very low, indicating that they are biosynthesized immediately before hormone-stimulated release.  PGs seem to be metabolized by all body tissues.  PGE and PGF cannot act as circulating hormones since they are 95-99% deactivated by 1 passage of the blood through the lungs.  The following roles of PGs in the reproductive process are discussed:  1) present in semen, they may aid in fertilization; 2) they may function as mediators between luteinizing hormone and cyclic AMP during ovulation; 3) they may facilitate release of anterior pituitary hormones; 4) they act to stimulate progesterone secretion; 5) they act in some species as the uterine luteolytic hormone; and 6) they sensitize the uterus to oxytocin during delivery.  Since every body tissue appears to be able to synthesize PGs, they also have other physiological functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359987"}
{"pmid": "4359990", "title": "Studies on 1-beta-D-arabinofuranosyl-cytosine-resistant mutants of Chinese-hamster fibroblasts. A mitochondrial deoxycytidine kinase devoid of activity on arabino-cytosine.", "content": "Studies on 1-beta-D-arabinofuranosyl-cytosine-resistant mutants of Chinese-hamster fibroblasts. A mitochondrial deoxycytidine kinase devoid of activity on arabino-cytosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359990"}
{"pmid": "4359984", "title": "The treatment of some neoplastic diseases in children with a new cytostatic drug: peptichemio. Investigations of a possible interference with lymphocyte blastogenesis and chromosomes.", "content": "The treatment of some neoplastic diseases in children with a new cytostatic drug: peptichemio. Investigations of a possible interference with lymphocyte blastogenesis and chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359984"}
{"pmid": "4359991", "title": "Effects of 5'-amido analogues of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphothioate on protein kinase, binding protein and phosphodiesterases.", "content": "Effects of 5'-amido analogues of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphothioate on protein kinase, binding protein and phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359991"}
{"pmid": "4359992", "title": "2-Amino-2,6-dideoxy-d-glucose (D-quinovosamine): a constituent of the lipopolysaccharides of Vibrio cholerae.", "content": "2-Amino-2,6-dideoxy-d-glucose (D-quinovosamine): a constituent of the lipopolysaccharides of Vibrio cholerae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359992"}
{"pmid": "4359993", "title": "A nuclear-magnetic-resonance study of the manganese-thiamine-pyrophosphate complex in solution.", "content": "A nuclear-magnetic-resonance study of the manganese-thiamine-pyrophosphate complex in solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359993"}
{"pmid": "4359994", "title": "Studies on the induction of nitrate reductase by nitrite in bean-seed cotyledons.", "content": "Studies on the induction of nitrate reductase by nitrite in bean-seed cotyledons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359994"}
{"pmid": "4359995", "title": "Clinical evaluation of indoramin, a new antihypertensive agent.", "content": "Clinical evaluation of indoramin, a new antihypertensive agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4359995"}
{"pmid": "4360018", "title": "The lactose system in Klebsiella aerogenes V9A. 3. Specific repression of the lac operon by melibiose and raffinose.", "content": "The lactose system in Klebsiella aerogenes V9A. 3. Specific repression of the lac operon by melibiose and raffinose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360018"}
{"pmid": "4360020", "title": "Suspected adenoviral infection in adult dairy cattle.", "content": "Suspected adenoviral infection in adult dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360020"}
{"pmid": "4360021", "title": "Effects of bovine viral diarrhea and parainfluenza-3 virus vaccines on development of respiratory tract disease in calves.", "content": "Effects of bovine viral diarrhea and parainfluenza-3 virus vaccines on development of respiratory tract disease in calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360021"}
{"pmid": "4360022", "title": "Big ACTH: conversion to biologically active ACTH by trypsin.", "content": "Big ACTH: conversion to biologically active ACTH by trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360022"}
{"pmid": "4360023", "title": "Metabolism of endogenous proinsulin and insulin in man.", "content": "Metabolism of endogenous proinsulin and insulin in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360023"}
{"pmid": "4360024", "title": "Insulin receptors in the plasma membranes of human placenta.", "content": "Insulin receptors in the plasma membranes of human placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360024"}
{"pmid": "4360025", "title": "Cyclic adenosine monophosphate stimulates secretion of human chorionic gonadotropin and estrogens by human trophoblast in vitro.", "content": "Cyclic adenosine monophosphate stimulates secretion of human chorionic gonadotropin and estrogens by human trophoblast in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360025"}
{"pmid": "4360026", "title": "Complementation of translational defect for growth of human adenovirus type 2 in Simian cells by a Simian virus 40-induced factor.", "content": "Complementation of translational defect for growth of human adenovirus type 2 in Simian cells by a Simian virus 40-induced factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360026"}
{"pmid": "4360027", "title": "Rotational relaxation time of concanavalin A bound to the surface membrane of normal and malignant transformed cells.", "content": "Rotational relaxation time of concanavalin A bound to the surface membrane of normal and malignant transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360027"}
{"pmid": "4360031", "title": "Selective inhibition of aldosterone synthesis by 11-hydroxylated spirolactone in rat adrenals.", "content": "Selective inhibition of aldosterone synthesis by 11-hydroxylated spirolactone in rat adrenals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360031"}
{"pmid": "4360030", "title": "Neurotransmitter uptake: a tool in identifying neurotransmitter-specific pathways.", "content": "Neurotransmitter uptake: a tool in identifying neurotransmitter-specific pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360030"}
{"pmid": "4360032", "title": "Nerve sheath myxoma in the tongue.", "content": "Nerve sheath myxoma in the tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360032"}
{"pmid": "4360033", "title": "Surgical management of recurrent head and neck cancer.", "content": "Surgical management of recurrent head and neck cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360033"}
{"pmid": "4360034", "title": "Radiotherapy for postoperative persistent cancer of the head and neck.", "content": "Radiotherapy for postoperative persistent cancer of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360034"}
{"pmid": "4360036", "title": "The sensitivity to 5-hydroxytryptamine of various parts of the gastro-intestinal tract of the rats with experimental gastric ulcers.", "content": "The sensitivity to 5-hydroxytryptamine of various parts of the gastro-intestinal tract of the rats with experimental gastric ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360036"}
{"pmid": "4360035", "title": "Cryosurgery for recurrent cancer of the head and neck.", "content": "Cryosurgery for recurrent cancer of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360035"}
{"pmid": "4360037", "title": "Respiratory symptoms and rash in mumps.", "content": "Respiratory symptoms and rash in mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360037"}
{"pmid": "4360039", "title": "Experimental silicosis. The relation between dose of quartz, length of action for the dust, tissue reaction and disturbance of the lung function.", "content": "Experimental silicosis. The relation between dose of quartz, length of action for the dust, tissue reaction and disturbance of the lung function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360039"}
{"pmid": "4360047", "title": "Renal hypertension in children.", "content": "Renal hypertension in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360047"}
{"pmid": "4360046", "title": "Aromatization of the A-ring of norethynodrel, a steroidal oral contraceptive, during trimethylsilylation.", "content": "Aromatization of the A-ring of norethynodrel, a steroidal oral contraceptive, during trimethylsilylation. Treatment of the steroidal oral contraceptive, norethynodrel (Ia), under persilylation conditions with trimethylsilylimidazole yielded two products: 17 alpha-ethynyl-3,5(10)-estradien-3, 17 beta-diTMS (IIa) and 17  alpha-ethynyl-1,3,5(10)-estratrien-3,17 beta-diTMS (IIIa).  Extended reaction time at 100 degrees C yielded only IIIa, the aromatic substance.  A second steroid, 5(10)-estren-17 beta-ol-3-one (LB), gave the corresponding (IIb (iib and IIIb).  Both aromatic compounds were characterized by gas chromatography-mass spectrometry comparisons with the diTMS-derivatives of the corresponding estradiols.  The mechanism of the aromatization reaction is unknown, but was probably one of dehydrogenation rather than of oxysilylation followed by loss of trimethylsilanol and aromatization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360046"}
{"pmid": "4360050", "title": "Effects of isoflurane and halothane on contractility and the cyclic 3', 5'-adenosine monophosphate system in the rat aorta.", "content": "Effects of isoflurane and halothane on contractility and the cyclic 3', 5'-adenosine monophosphate system in the rat aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360050"}
{"pmid": "4360051", "title": "Pregnancy in a patient with hormone deficiency.", "content": "Pregnancy in a patient with hormone deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360051"}
{"pmid": "4360052", "title": "Capacitance, area, and thickness variations in thin lipid films.", "content": "Capacitance, area, and thickness variations in thin lipid films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360052"}
{"pmid": "4360053", "title": "Proceedings: Correlations between certain biochemical properties of breast cancer and response to therapy: a preliminary report.", "content": "Proceedings: Correlations between certain biochemical properties of breast cancer and response to therapy: a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360053"}
{"pmid": "4360054", "title": "Proceedings: Primary oropharyngeal cancer and hypercalcemia.", "content": "Proceedings: Primary oropharyngeal cancer and hypercalcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360054"}
{"pmid": "4360056", "title": "Proceedings: Immunotherapy of malignant disease: the use of viable sensitized lymphocytes or transfer factor prepared from sensitized lymphocytes.", "content": "Proceedings: Immunotherapy of malignant disease: the use of viable sensitized lymphocytes or transfer factor prepared from sensitized lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360056"}
{"pmid": "4360055", "title": "Proceedings: Treatment of minimal breast cancer.", "content": "Proceedings: Treatment of minimal breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360055"}
{"pmid": "4360057", "title": "Proceedings: Primary liver cancer. A review of the clinical features, blood groups, serum enzymes, therapy, and survival of 65 cases.", "content": "Proceedings: Primary liver cancer. A review of the clinical features, blood groups, serum enzymes, therapy, and survival of 65 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360057"}
{"pmid": "4360064", "title": "Continuing surveillance of families for studying the epidemiology of viral infections.", "content": "Continuing surveillance of families for studying the epidemiology of viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360064"}
{"pmid": "4360065", "title": "Survey of recent literature on the menstrual cycle and behavior.", "content": "Survey of recent literature on the menstrual cycle and behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360065"}
{"pmid": "4360066", "title": "Ultrastructural studies of eight cases of fetal Tay-Sachs disease.", "content": "Ultrastructural studies of eight cases of fetal Tay-Sachs disease. 7 fetuses of 27 high risk pregnancies showed absence of hexosaminidase A and were aborted.  In all 7 cases, biochemical examination of fetal tissue confirmed the diagnosis.  In the brains of the Tay-Sachs disease fetuses electronmicroscopy showed an increase in G-M2 ganglioside and absence of hexosaminidase A.  By 12 weeks gestation abnormal cytoplasmic inclusions were present in the spinal cord.  By 22 weeks, ganglion cells of the retina and spinal ganglia showed alteration of cellular organelles and abnormal lipid material in the cytoplasm.  Attempts at enzyme replacement were unseccessful.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360066"}
{"pmid": "4360063", "title": "The pathogenesis of cholera and some wider implications.", "content": "The pathogenesis of cholera and some wider implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360063"}
{"pmid": "4360067", "title": "The type II epithelial cell of the lung. I. Method of isolation.", "content": "The type II epithelial cell of the lung. I. Method of isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360067"}
{"pmid": "4360068", "title": "Enzymatic solubilization and separation of glomerular collagen and sialoprotein. Effect of contaminating enzymes present in commercial collagenase preparations.", "content": "Enzymatic solubilization and separation of glomerular collagen and sialoprotein. Effect of contaminating enzymes present in commercial collagenase preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360068"}
{"pmid": "4360071", "title": "Erythrocyte enzymes and glycolytic intermediates of high- and low-glutathione sheep.", "content": "Erythrocyte enzymes and glycolytic intermediates of high- and low-glutathione sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360071"}
{"pmid": "4360075", "title": "Dehydration of macromolecules. II. Protective effects of certain anions on ribulosediphosphate carboxylase subjected to low water potenials in vitro.", "content": "Dehydration of macromolecules. II. Protective effects of certain anions on ribulosediphosphate carboxylase subjected to low water potenials in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360075"}
{"pmid": "4360074", "title": "Effect of naftidrofuryl upon energy metabolism of the brain.", "content": "Effect of naftidrofuryl upon energy metabolism of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360074"}
{"pmid": "4360077", "title": "Biological implications of the instability of the N-glycosidic bone of 3-methyldeoxyadenosine in DNA.", "content": "Biological implications of the instability of the N-glycosidic bone of 3-methyldeoxyadenosine in DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360077"}
{"pmid": "4360076", "title": "On the binding and specificity of 3,6-bis-(acetatomercurimethyl)-dioxane to DNAs of different base composition.", "content": "On the binding and specificity of 3,6-bis-(acetatomercurimethyl)-dioxane to DNAs of different base composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360076"}
{"pmid": "4360078", "title": "Comparison of the acceptance activity of the ribosome-bound and the total cellular transfer ribonucleic acids from SV40-transformed mouse fibroblasts.", "content": "Comparison of the acceptance activity of the ribosome-bound and the total cellular transfer ribonucleic acids from SV40-transformed mouse fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360078"}
{"pmid": "4360082", "title": "Receptor mechanism concepts.", "content": "Receptor mechanism concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360082"}
{"pmid": "4360081", "title": "The effect of N6-2'-O dibutyryl 3',5' cyclic adenosine monophosphate, imidazole and aminophylline on ganglionic transmission in the superior cervical ganglion of the cat.", "content": "The effect of N6-2'-O dibutyryl 3',5' cyclic adenosine monophosphate, imidazole and aminophylline on ganglionic transmission in the superior cervical ganglion of the cat. 1. Dibutyryl cyclic AMP, injected towards the superior cervical ganglion of the cat, produced no consistent responses.2. Imidazole, injected towards the ganglion, regularly produced facilitation, both during intermittent and continuous preganglionic stimulation. This effect was dose-dependent and lasted 2-10 minutes.3. Aminophylline, injected towards the ganglion, regularly produced depression of ganglionic transmission, both during intermittent and continuous preganglionic stimulation. This effect was also dose-dependent and lasted 1-4 minutes. Papaverine produced the same type of response as aminophylline.4. Imidazole potentiated the ganglionic response to 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP), while aminophylline depressed it.5. The results of the present experiments are consistent with the view that cyclic AMP may have a mediating role in the process of ganglionic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360081"}
{"pmid": "4360069", "title": "Angiotensin I as a dipsogen: efficacy in brain independent of conversion to angiotensin II.", "content": "Angiotensin I as a dipsogen: efficacy in brain independent of conversion to angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360069"}
{"pmid": "4360084", "title": "Vasopressors in obstetrics.", "content": "Vasopressors in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360084"}
{"pmid": "4360083", "title": "Antibiotics.", "content": "Antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360083"}
{"pmid": "4360085", "title": "Rapid gas chromatographic assay for dehydroepiandrosterone in urine.", "content": "Rapid gas chromatographic assay for dehydroepiandrosterone in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360085"}
{"pmid": "4360086", "title": "A program for assessing the effect of treatment on growth and development in children with growth disorders.", "content": "A program for assessing the effect of treatment on growth and development in children with growth disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360086"}
{"pmid": "4360087", "title": "Chromatin, and gene regulation in eukaryotic cells at the transcriptional level.", "content": "Chromatin, and gene regulation in eukaryotic cells at the transcriptional level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360087"}
{"pmid": "4360080", "title": "Succinate dehydrogenase and cytochrome C oxidase activity of antigen stimulated macrophages.", "content": "Succinate dehydrogenase and cytochrome C oxidase activity of antigen stimulated macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360080"}
{"pmid": "4360091", "title": "Surface biochemical changes accompanying primary infection with Rous sarcoma virus. I. Electrokinetic properties of cells and cell surface glycoprotein:glycosyl transferase activities.", "content": "Surface biochemical changes accompanying primary infection with Rous sarcoma virus. I. Electrokinetic properties of cells and cell surface glycoprotein:glycosyl transferase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360091"}
{"pmid": "4360092", "title": "Nuclear cytochemical changes in rat adrenal glands stimulated by adrenocorticotrophic hormone.", "content": "Nuclear cytochemical changes in rat adrenal glands stimulated by adrenocorticotrophic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360092"}
{"pmid": "4360093", "title": "Periodate-induced lymphocyte transformation. 3. Effects of temperature and pH.", "content": "Periodate-induced lymphocyte transformation. 3. Effects of temperature and pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360093"}
{"pmid": "4360094", "title": "Surface biochemical changes accompanying primary infection with Rous sarcoma virus. II. Proteolytic and glycosidase activity and sublethal autolysis.", "content": "Surface biochemical changes accompanying primary infection with Rous sarcoma virus. II. Proteolytic and glycosidase activity and sublethal autolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360094"}
{"pmid": "4360095", "title": "Reactivation of chick erythrocyte nuclei in heterokaryons with rat hepatoma cells.", "content": "Reactivation of chick erythrocyte nuclei in heterokaryons with rat hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360095"}
{"pmid": "4360096", "title": "The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells.", "content": "The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360096"}
{"pmid": "4360097", "title": "Heavy metals and spermatozoan motility. II. Turbidity changes induced by divalent cations and adenosinetriphosphate in sea urchin sperm flagella.", "content": "Heavy metals and spermatozoan motility. II. Turbidity changes induced by divalent cations and adenosinetriphosphate in sea urchin sperm flagella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360097"}
{"pmid": "4360098", "title": "Dipyrone as a cause of drug rashes: an epidemiologic study.", "content": "Dipyrone as a cause of drug rashes: an epidemiologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360098"}
{"pmid": "4360099", "title": "Cytochrome oxidase activity of mitochondria in sensory nerve endings of mouse palatal rugae.", "content": "Cytochrome oxidase activity of mitochondria in sensory nerve endings of mouse palatal rugae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360099"}
{"pmid": "4360100", "title": "Clinical pathological conference. The man without history.", "content": "Clinical pathological conference. The man without history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360100"}
{"pmid": "4360101", "title": "Different binding of RNA polymerase to individual promoters.", "content": "Different binding of RNA polymerase to individual promoters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360101"}
{"pmid": "4360102", "title": "Mutants of Escherichia coli unable to metabolize cytidine: isolation and characterization.", "content": "Mutants of Escherichia coli unable to metabolize cytidine: isolation and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360102"}
{"pmid": "4360107", "title": "Melanotic neuroectodermal tumor of infancy. A case report and review.", "content": "Melanotic neuroectodermal tumor of infancy. A case report and review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360107"}
{"pmid": "4360108", "title": "Protocollagen proline hydroxylase activity in human dental pulp at various stages of development.", "content": "Protocollagen proline hydroxylase activity in human dental pulp at various stages of development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360108"}
{"pmid": "4360111", "title": "Endotoxin-induced alterations in isolated fat cells: effect on norepinephrine-stimulated lipolysis and cyclic 3',5'-adenosine monophosphate accumulation.", "content": "Endotoxin-induced alterations in isolated fat cells: effect on norepinephrine-stimulated lipolysis and cyclic 3',5'-adenosine monophosphate accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360111"}
{"pmid": "4360109", "title": "Peripheral vascular actions of alpha-methyl-DOPA and its mode of action on arterioles.", "content": "Peripheral vascular actions of alpha-methyl-DOPA and its mode of action on arterioles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360109"}
{"pmid": "4360110", "title": "Isolated adrenal cortex cells: ACTH4-23 (NH2), ACTH5-24, ACTH6-24 and ACTH7-23 (NH2); cyclic AMP and corticosterone production.", "content": "Isolated adrenal cortex cells: ACTH4-23 (NH2), ACTH5-24, ACTH6-24 and ACTH7-23 (NH2); cyclic AMP and corticosterone production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360110"}
{"pmid": "4360112", "title": "Characterization of gluconeogenesis in enzymatically isolated parenchymal cells of rat liver.", "content": "Characterization of gluconeogenesis in enzymatically isolated parenchymal cells of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360112"}
{"pmid": "4360113", "title": "The everted rat intestine used as a model system to demonstrate regulation of sodium absorption following hemorrhage.", "content": "The everted rat intestine used as a model system to demonstrate regulation of sodium absorption following hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360113"}
{"pmid": "4360114", "title": "Calcium-secretagogue interaction in the stimulation of gastric acid secretion.", "content": "Calcium-secretagogue interaction in the stimulation of gastric acid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360114"}
{"pmid": "4360115", "title": "Radiation-enhanced survival of a human virus in normal and malignant rat cells.", "content": "Radiation-enhanced survival of a human virus in normal and malignant rat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360115"}
{"pmid": "4360116", "title": "Correlation of C-type virus (WF-1) production and heme synthesis in a rat fibroblastic cell line.", "content": "Correlation of C-type virus (WF-1) production and heme synthesis in a rat fibroblastic cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360116"}
{"pmid": "4360117", "title": "Effect of glucosamine administration in normal rats in comparison with streptozotocin treatment.", "content": "Effect of glucosamine administration in normal rats in comparison with streptozotocin treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360117"}
{"pmid": "4360118", "title": "Regulation of gingival collagenase: a possible role for a mast cell factor.", "content": "Regulation of gingival collagenase: a possible role for a mast cell factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360118"}
{"pmid": "4360119", "title": "The effect of cold on the composition of the phospholipids of the blood plasma of healthy athletes.", "content": "The effect of cold on the composition of the phospholipids of the blood plasma of healthy athletes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360119"}
{"pmid": "4360120", "title": "Functions of the mammalian cerebral cortex in movement.", "content": "Functions of the mammalian cerebral cortex in movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360120"}
{"pmid": "4360122", "title": "Heterogeneity of enzymes in leukaemic eosinophils.", "content": "Heterogeneity of enzymes in leukaemic eosinophils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360122"}
{"pmid": "4360121", "title": "Studies on the neural control of the skating reflex, and the origin of its variations in field population of the hemipterous insect Gerris.", "content": "Studies on the neural control of the skating reflex, and the origin of its variations in field population of the hemipterous insect Gerris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360121"}
{"pmid": "4360128", "title": "Cyclic adenosine 3',5'-monophosphate dependent protein kinase of human platelets: membrane phosphorylation and regulation of platelet function.", "content": "Cyclic adenosine 3',5'-monophosphate dependent protein kinase of human platelets: membrane phosphorylation and regulation of platelet function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360128"}
{"pmid": "4360127", "title": "Interactions of the pharmacological receptors of blood platelets with adenylate cyclase.", "content": "Interactions of the pharmacological receptors of blood platelets with adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360127"}
{"pmid": "4360129", "title": "The release reaction: is it a common mechanism in all types of hemostatic cells?", "content": "The release reaction: is it a common mechanism in all types of hemostatic cells?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360129"}
{"pmid": "4360130", "title": "Neonatal familial type II hyperlipoproteinemia: cord blood cholesterol and follow up study in 1.323 births.", "content": "Neonatal familial type II hyperlipoproteinemia: cord blood cholesterol and follow up study in 1.323 births.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360130"}
{"pmid": "4360131", "title": "Long term follow-up of the paced patients.", "content": "Long term follow-up of the paced patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360131"}
{"pmid": "4360133", "title": "Obstructive uropathy secondary to calcified metastatic adenocarcinoma of colon.", "content": "Obstructive uropathy secondary to calcified metastatic adenocarcinoma of colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360133"}
{"pmid": "4360132", "title": "Bilateral Wilms' tumor. Treatment, management, and review of the literature.", "content": "Bilateral Wilms' tumor. Treatment, management, and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360132"}
{"pmid": "4360138", "title": "A micro assay for mouse and human interferon. II. Dose-response in different in cell-virus systems.", "content": "A micro assay for mouse and human interferon. II. Dose-response in different in cell-virus systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360138"}
{"pmid": "4360139", "title": "Immunofluorescence measurement of C1 inactivator (alpha 2 neuraminoglycoprotein) activity of the surface of human carcinoma cells.", "content": "Immunofluorescence measurement of C1 inactivator (alpha 2 neuraminoglycoprotein) activity of the surface of human carcinoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360139"}
{"pmid": "4360140", "title": "Stability of human leukocyte interferon towards heat.", "content": "Stability of human leukocyte interferon towards heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360140"}
{"pmid": "4360141", "title": "Diagnostic scoring system for mammary carcinoma.", "content": "Diagnostic scoring system for mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360141"}
{"pmid": "4360142", "title": "Lymphoid cells in carcinoma of the breast. Failure of response to phytohaemagglutinin in vitro.", "content": "Lymphoid cells in carcinoma of the breast. Failure of response to phytohaemagglutinin in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360142"}
{"pmid": "4360143", "title": "Amyotrophic lateral sclerosis. Electrophysiologic study (number of motor units and rate of decay of motor units).", "content": "Amyotrophic lateral sclerosis. Electrophysiologic study (number of motor units and rate of decay of motor units).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360143"}
{"pmid": "4360144", "title": "Multiple muscle analysis of motor units in muscular dystrophy.", "content": "Multiple muscle analysis of motor units in muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360144"}
{"pmid": "4360145", "title": "Hereditary brachial neuropathy. Report of two families.", "content": "Hereditary brachial neuropathy. Report of two families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360145"}
{"pmid": "4360146", "title": "Folate deficiency and neurological disease. One case with a close association.", "content": "Folate deficiency and neurological disease. One case with a close association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360146"}
{"pmid": "4360147", "title": "Interspecies infection by feline leukemia virus: serial cell-free transmission in dogs of malignant lymphomas induced by feline leukemia virus.", "content": "Interspecies infection by feline leukemia virus: serial cell-free transmission in dogs of malignant lymphomas induced by feline leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360147"}
{"pmid": "4360148", "title": "Burkitt's lymphoma: cell kinetics, treatment and immunology.", "content": "Burkitt's lymphoma: cell kinetics, treatment and immunology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360148"}
{"pmid": "4360149", "title": "Viral envelope antigens of the viruses of feline leukemia-sarcoma complex.", "content": "Viral envelope antigens of the viruses of feline leukemia-sarcoma complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360149"}
{"pmid": "4360150", "title": "Significance of leukemia in animals for the human disease.", "content": "Significance of leukemia in animals for the human disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360150"}
{"pmid": "4360151", "title": "Structural and serological studies on animal 'C-type particles' and their implications for demonstrating corresponding viruses in man.", "content": "Structural and serological studies on animal 'C-type particles' and their implications for demonstrating corresponding viruses in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360151"}
{"pmid": "4360152", "title": "Studies on the relationship of RNA viruses to the origin of leukemia and solid tumors of animals and man.", "content": "Studies on the relationship of RNA viruses to the origin of leukemia and solid tumors of animals and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360152"}
{"pmid": "4360153", "title": "Electron microscopy of feline leukaemia virus RNA.", "content": "Electron microscopy of feline leukaemia virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360153"}
{"pmid": "4360154", "title": "Electron microscopy of early interactions between feline leukaemia virus and cells in tissue culture.", "content": "Electron microscopy of early interactions between feline leukaemia virus and cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360154"}
{"pmid": "4360155", "title": "Role of C-type virus in bovine lymphosarcoma.", "content": "Role of C-type virus in bovine lymphosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360155"}
{"pmid": "4360157", "title": "Continuing studies of feline sarcoma virus-induced tumors in nonhuman primates.", "content": "Continuing studies of feline sarcoma virus-induced tumors in nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360157"}
{"pmid": "4360158", "title": "Biological studies in four species of nonhuman primates with simian sarcoma virus (Lagothrix).", "content": "Biological studies in four species of nonhuman primates with simian sarcoma virus (Lagothrix).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360158"}
{"pmid": "4360156", "title": "A comparative study in vitro of a simian virus isolated from spontaneous woolly monkey fibrosarcoma and of a known feline fibrosarcoma virus.", "content": "A comparative study in vitro of a simian virus isolated from spontaneous woolly monkey fibrosarcoma and of a known feline fibrosarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360156"}
{"pmid": "4360160", "title": "The epidemiologic and genetic aspects of an outbreak of leukemia among Hamadryas baboons of the Sukhumi monkey colony.", "content": "The epidemiologic and genetic aspects of an outbreak of leukemia among Hamadryas baboons of the Sukhumi monkey colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360160"}
{"pmid": "4360159", "title": "Simian sarcoma virus: oncogenicity, focus assay, presence of associated virus, and comparison with avian and feline sarcoma virus-induced neoplasia in marmoset monkeys.", "content": "Simian sarcoma virus: oncogenicity, focus assay, presence of associated virus, and comparison with avian and feline sarcoma virus-induced neoplasia in marmoset monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360159"}
{"pmid": "4360161", "title": "Structural components of a murine leukemia virus and the plasma membrane of virus infected cells.", "content": "Structural components of a murine leukemia virus and the plasma membrane of virus infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360161"}
{"pmid": "4360163", "title": "An analysis of antigens on the surface of murine leukemia viruses and cells.", "content": "An analysis of antigens on the surface of murine leukemia viruses and cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360163"}
{"pmid": "4360164", "title": "Etiological strain specificities of the avian tumor viruses.", "content": "Etiological strain specificities of the avian tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360164"}
{"pmid": "4360162", "title": "High resolution electron microscopy studies of murine leukemia viruses.", "content": "High resolution electron microscopy studies of murine leukemia viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360162"}
{"pmid": "4360166", "title": "Transmission and expression of the leukemia introducing agent in BALB-cf(R3) mice.", "content": "Transmission and expression of the leukemia introducing agent in BALB-cf(R3) mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360166"}
{"pmid": "4360167", "title": "Demonstration of helper activity with human leukemic tissue extracts.", "content": "Demonstration of helper activity with human leukemic tissue extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360167"}
{"pmid": "4360165", "title": "Studies of interferon and murine leukemia sarcoma virus group.", "content": "Studies of interferon and murine leukemia sarcoma virus group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360165"}
{"pmid": "4360169", "title": "Spleen focus assays with a mouse leukemia virus in mice treated with actinomycin D, L-asparaginase or rifampicin.", "content": "Spleen focus assays with a mouse leukemia virus in mice treated with actinomycin D, L-asparaginase or rifampicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360169"}
{"pmid": "4360171", "title": "In vitro transformation of leukocytes with a guinea pig herpes-like virus.", "content": "In vitro transformation of leukocytes with a guinea pig herpes-like virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360171"}
{"pmid": "4360170", "title": "Effects of STAS JLSV5 and silicotungstate on the replication of murine sarcoma virus (Moloney) and poliovirus.", "content": "Effects of STAS JLSV5 and silicotungstate on the replication of murine sarcoma virus (Moloney) and poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360170"}
{"pmid": "4360168", "title": "Immunizing and interfering action of non-leukemogenic C-type murine virus variants in leukemogenesis.", "content": "Immunizing and interfering action of non-leukemogenic C-type murine virus variants in leukemogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360168"}
{"pmid": "4360172", "title": "Studies on oncogenic properties of Epstein-Barr virus.", "content": "Studies on oncogenic properties of Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360172"}
{"pmid": "4360173", "title": "Persistence of Epstein-Barr virus DNA in human tumor cells.", "content": "Persistence of Epstein-Barr virus DNA in human tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360173"}
{"pmid": "4360174", "title": "The possible significance of morphological transformation of human fibroblasts by EB virus in vitro.", "content": "The possible significance of morphological transformation of human fibroblasts by EB virus in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360174"}
{"pmid": "4360176", "title": "Purification of Herpesvirus saimiri DNA.", "content": "Purification of Herpesvirus saimiri DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360176"}
{"pmid": "4360175", "title": "A prospective sero-epidemiological study to investigate the role of EBV in Burkitt's lymphoma.", "content": "A prospective sero-epidemiological study to investigate the role of EBV in Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360175"}
{"pmid": "4360177", "title": "Studies on the interrelationship of type B and type C virus particles in breast cancer and in leukemia.", "content": "Studies on the interrelationship of type B and type C virus particles in breast cancer and in leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360177"}
{"pmid": "4360179", "title": "Minor base changes in transfer ribonucleic acid in avian myeloblastosis virus.", "content": "Minor base changes in transfer ribonucleic acid in avian myeloblastosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360179"}
{"pmid": "4360178", "title": "The 60-70S RNA of avian sarcoma and leukosis viruses--distribution of class a and b subunits.", "content": "The 60-70S RNA of avian sarcoma and leukosis viruses--distribution of class a and b subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360178"}
{"pmid": "4360180", "title": "Presence of avian leukosis virus genes, in DNA form in normal chickens.", "content": "Presence of avian leukosis virus genes, in DNA form in normal chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360180"}
{"pmid": "4360181", "title": "A comparative study of Marek's disease virus proteins.", "content": "A comparative study of Marek's disease virus proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360181"}
{"pmid": "4360182", "title": "Chromosomes of viral-transformed BALB-c-3T3 cells.", "content": "Chromosomes of viral-transformed BALB-c-3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360182"}
{"pmid": "4360185", "title": "Possible activation of C-type particles during 'progression' of the chemically-induced pulmonary tumors in mice.", "content": "Possible activation of C-type particles during 'progression' of the chemically-induced pulmonary tumors in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360185"}
{"pmid": "4360184", "title": "RNA tumor virus antigen expression in chemically-induced tumors. Significance of specific chemical carcinogens to the derepression of the C-type RNA virogene and oncogene expressions.", "content": "RNA tumor virus antigen expression in chemically-induced tumors. Significance of specific chemical carcinogens to the derepression of the C-type RNA virogene and oncogene expressions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360184"}
{"pmid": "4360187", "title": "Isolation and characterization of the hamster C-type viruses.", "content": "Isolation and characterization of the hamster C-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360187"}
{"pmid": "4360183", "title": "Chemical co-carcinogenesis: differential action of various compounds, derepression of endogenous C-type RNA genomes, and influence of different genotypes of mice.", "content": "Chemical co-carcinogenesis: differential action of various compounds, derepression of endogenous C-type RNA genomes, and influence of different genotypes of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360183"}
{"pmid": "4360186", "title": "RNA tumor virus genomes as determinants of chemically-induced transformation in vitro.", "content": "RNA tumor virus genomes as determinants of chemically-induced transformation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360186"}
{"pmid": "4360188", "title": "In vitro carcinogenesis studies: dual effect of RNA tumor viruses and carcinogenic chemicals or DNA viruses.", "content": "In vitro carcinogenesis studies: dual effect of RNA tumor viruses and carcinogenic chemicals or DNA viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360188"}
{"pmid": "4360189", "title": "Influence of immune suppression on the induction of neoplasms by MLV and MSV.", "content": "Influence of immune suppression on the induction of neoplasms by MLV and MSV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360189"}
{"pmid": "4360190", "title": "The role of immunity in radiation leukemogenesis.", "content": "The role of immunity in radiation leukemogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360190"}
{"pmid": "4360191", "title": "Homologous and heterologous immunization against Rous sarcoma.", "content": "Homologous and heterologous immunization against Rous sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360191"}
{"pmid": "4360192", "title": "Isolation and characterization of the A-type of latent hamster virus.", "content": "Isolation and characterization of the A-type of latent hamster virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360192"}
{"pmid": "4360193", "title": "Antibodies in chickens against avian leukosis virus group specific antigen.", "content": "Antibodies in chickens against avian leukosis virus group specific antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360193"}
{"pmid": "4360194", "title": "Relationship between humoral antibodies and the failure to develop progressive tumors in cats injected with feline sarcoma virus (FSV).", "content": "Relationship between humoral antibodies and the failure to develop progressive tumors in cats injected with feline sarcoma virus (FSV).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360194"}
{"pmid": "4360195", "title": "Detection of the feline leukemia virus and other mammalian oncornaviruses by immunofluorescence.", "content": "Detection of the feline leukemia virus and other mammalian oncornaviruses by immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360195"}
{"pmid": "4360197", "title": "Studies of human cells infected by leukemia viruses.", "content": "Studies of human cells infected by leukemia viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360197"}
{"pmid": "4360198", "title": "EBV antibody in monkeys and apes.", "content": "EBV antibody in monkeys and apes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360198"}
{"pmid": "4360196", "title": "Antibodies to Epstein-Barr virus associated antigens in Burkitt's lymphoma.", "content": "Antibodies to Epstein-Barr virus associated antigens in Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360196"}
{"pmid": "4360199", "title": "Avian virus-induced leukemia-a model of cell differentiation.", "content": "Avian virus-induced leukemia-a model of cell differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360199"}
{"pmid": "4360200", "title": "Feline leukaemia virus infection--the spectrum of associated disease and its relevance to the pathogenesis and immunology of leukaemia.", "content": "Feline leukaemia virus infection--the spectrum of associated disease and its relevance to the pathogenesis and immunology of leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360200"}
{"pmid": "4360201", "title": "Cell kinetics of virally-induced leukemias.", "content": "Cell kinetics of virally-induced leukemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360201"}
{"pmid": "4360202", "title": "Guanine metabolism in preimplantation mouse embryo.", "content": "Guanine metabolism in preimplantation mouse embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360202"}
{"pmid": "4360203", "title": "Interaction of Sendai virus and rabbit sperm: transmission and scanning electron microscopy.", "content": "Interaction of Sendai virus and rabbit sperm: transmission and scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360203"}
{"pmid": "4360204", "title": "Hormonal effects of estrogen-protein conjugates on rat uterus.", "content": "Hormonal effects of estrogen-protein conjugates on rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360204"}
{"pmid": "4360211", "title": "Therapy strategies, personality orientation and recovery from alcoholism.", "content": "Therapy strategies, personality orientation and recovery from alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360211"}
{"pmid": "4360214", "title": "Storage and activity of prostaglandin-like substance in body tissues of rats fed high fat diets.", "content": "Storage and activity of prostaglandin-like substance in body tissues of rats fed high fat diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360214"}
{"pmid": "4360213", "title": "Family planning: hospitals should expand services.", "content": "Family planning: hospitals should expand services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360213"}
{"pmid": "4360215", "title": "Bone case of the month.", "content": "Bone case of the month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360215"}
{"pmid": "4360217", "title": "Thin fat people.", "content": "Thin fat people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360217"}
{"pmid": "4360216", "title": "Distribution of women physicians, 1971.", "content": "Distribution of women physicians, 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360216"}
{"pmid": "4360218", "title": "Do oral contraceptives need to be interrupted in order to treat vaginal candidiasis?", "content": "Do oral contraceptives need to be interrupted in order to treat vaginal candidiasis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360218"}
{"pmid": "4360219", "title": "Improved Gram's stain for buffy coat smears.", "content": "Improved Gram's stain for buffy coat smears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360219"}
{"pmid": "4360220", "title": "Levels of nicotinamide adenine dinucleotide and reduced nicotinamide adenine dinucleotide in facultative bacteria and the effect of oxygen.", "content": "Levels of nicotinamide adenine dinucleotide and reduced nicotinamide adenine dinucleotide in facultative bacteria and the effect of oxygen. Nicotinamide adenine dinucleotide (NAD) and reduced NAD (NADH) levels have been measured in bacterial cultures. The cofactors were assayed by using the very sensitive cycling assay described previously by Cartier. Control experiments showed that the level of total NAD(H) falls during harvesting, and so samples were taken quickly from growing cultures and extracted immediately without separating the cells from the medium. Total NAD(H) ranged from 4.0 to 11.7 mumoles/g of dry cells for three facultative organisms, Klebsiella aerogenes, Escherichia coli, and Staphylococcus albus. NADH was remarkably constant in these bacteria; only one out of ten series of determinations was outside the range 1.4 to 1.9 mumoles/g of dry cells. NAD(+) showed much greater variation. An anaerobe (Clostridium welchii) had significantly more total NAD(H) whereas an aerobe Pseudomonas aeruginosa had about as much NAD(H) as the facultative organisms. NAD and NADH were measured during growth: once more NADH was much more constant than NAD. During change-over between aerobiosis and anaerobiosis, NADH showed a temporary increase but then returned to a constant level, whereas NAD changed from high aerobically to low anaerobically. These results are discussed in terms of the control mechanisms that may be involved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360220"}
{"pmid": "4360221", "title": "Regulation of myo-inositol catabolism in Aerobacter aerogenes.", "content": "Regulation of myo-inositol catabolism in Aerobacter aerogenes. A mutant of Aerobacter aerogenes produces constitutively the series of enzymes that mediates the degradation of myo-inositol and which in the wildtype strain is inducible. When grown on l-histidine, the mutant forms the enzymes at a level approximately three times as high as that seen in the induced wild type. The enzymes appear to be coordinately regulated and are sensitive to catabolite repression. Unless repressed, the synthesis of these enzymes markedly retards the growth of the mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360221"}
{"pmid": "4360222", "title": "Kinetic properties of phosphotransacetylase from Veillonella alcalescens.", "content": "Kinetic properties of phosphotransacetylase from Veillonella alcalescens. The phosphotransacetylase of Veillonella alcalescens catalyzes a reversible reaction with Michaelis-Menten kinetics for all substrates. The rate of the reverse reaction (the synthesis of acetyl coenzyme A from acetyl phosphate) was 6.5 times greater than the rate of the forward reaction (the synthesis of acetyl phosphate from acetyl coenzyme A). The apparent K(m) values determined for the forward reaction were 8.6 x 10(-6)m for acetyl coenzyme A and 9.3 x 10(-3)m for phosphate. In the reverse reaction, the K(m) values were 3.3 x 10(-4)m for coenzyme A and 5.9 x 10(-4)m for acetyl phosphate. The results of an analysis of the inhibition by end products in the forward and reverse directions were compatible with a random bi- bi- mechanism. The enzyme was inhibited by adenosine triphosphate and adenosine diphosphate but was not affected by reduced nicotinamide adenine dinucleotide or pyruvate. The inhibition by adenosine triphosphate was noncompetitive with respect to acetyl phosphate and competitive with respect to coenzyme A. MgCl(2) reversed the inhibition by adenosine triphosphate or adenosine diphosphate. The role of Mg(2+) and adenylates in the regulation of phosphotranscetylase activity is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360222"}
{"pmid": "4360223", "title": "De novo biosynthesis of nicotinamide adenine dinucleotide in Escherichia coli: excretion of quinolinic acid by mutants lacking quinolinate phosphoribosyl transferase.", "content": "De novo biosynthesis of nicotinamide adenine dinucleotide in Escherichia coli: excretion of quinolinic acid by mutants lacking quinolinate phosphoribosyl transferase. The excretion of quinolinic acid was studied in growing and resting cells of Escherichia coli K-12 nadC(13). Under optimal conditions, this organism could synthesize quinolinic acid in several-fold excess of the amount which would be required for normal growth. The excretion of quinolinic acid was controlled by the concentration of nicotinamide adenine dinucleotide (NAD) precursors available to the organism either during growth or during incubation in dense cell suspensions. These observations suggest that biosynthesis of NAD de novo is regulated by both repression and feedback inhibition. Analogues of niacin which inhibit bacterial growth also inhibited and repressed the synthesis (excretion) of quinolinic acid. The pH optimum for quinolinic acid excretion agreed favorably with the optimum observed for its synthesis in vitro. The rate of quinolinic acid excretion was strongly influenced by the concentration of ribose or glycerol in the medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360223"}
{"pmid": "4360224", "title": "The pathogenicity of Entamoeba histolytica: is heat stress a factor?", "content": "The pathogenicity of Entamoeba histolytica: is heat stress a factor?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360224"}
{"pmid": "4360226", "title": "The nature of the establishment barrier for Trypanosoma brucei in the gut of Glossina pallidipes.", "content": "The nature of the establishment barrier for Trypanosoma brucei in the gut of Glossina pallidipes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360226"}
{"pmid": "4360227", "title": "Letter: Assay of serum enzymes in trypanosomal infection: interference by pyruvate.", "content": "Letter: Assay of serum enzymes in trypanosomal infection: interference by pyruvate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360227"}
{"pmid": "4360234", "title": "The use of isocyanides for the immobilization of biological molecules.", "content": "The use of isocyanides for the immobilization of biological molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360234"}
{"pmid": "4360235", "title": "The effects of nucleotides on the alpha-glucosidase formation in baker's yeast protoplasts.", "content": "The effects of nucleotides on the alpha-glucosidase formation in baker's yeast protoplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360235"}
{"pmid": "4360241", "title": "Control of in vivo luminescence in psychrophilic marine Photobacterium.", "content": "Control of in vivo luminescence in psychrophilic marine Photobacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360241"}
{"pmid": "4360248", "title": "Kinetic studies of the acylation of pig muscle D-glyceraldehyde 3-phosphate dehydrogenase by 1,3-diphosphoglycerate and of proton uptake and release in the overall enzyme mechanism.", "content": "Kinetic studies of the acylation of pig muscle D-glyceraldehyde 3-phosphate dehydrogenase by 1,3-diphosphoglycerate and of proton uptake and release in the overall enzyme mechanism. In the presence of NAD(+) the acylation by 1,3-diphosphoglycerate of the four active sites of pig muscle d-glyceraldehyde 3-phosphate dehydrogenase can be monitored at 365nm by the disappearance of the absorption band present in the binary complex of NAD(+) and the enzyme. A non-specific salt effect decreased the acylation rate 25-fold when the ionic strength was increased from 0.10 to 1.0. This caused acylation to be the rate-limiting process in the enzyme-catalysed reductive dephosphorylation of 1,3-diphosphoglycerate at high ionic strength at pH8. The salt effect permitted investigation of the acylation over a wide range of conditions. Variation of pH from 5.4 to 8.6 produced at most a two-fold change in the acylation rate. One proton was taken up per site acylated at pH8.0. By using a chromophoric H(+) indicator the rate of proton uptake could be monitored during the acylation and was also almost invariant in the pH range 5.5-8.5. Transient kinetic studies of the overall enzyme-catalysed reaction indicated that acylation was the process involving proton uptake at pH8.0. The enzyme mechanism is discussed in the light of these results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360248"}
{"pmid": "4360247", "title": "A comparison of the physical and chemical properties of four cytochromes c from Azotobacter vinelandii.", "content": "A comparison of the physical and chemical properties of four cytochromes c from Azotobacter vinelandii. 1. A modified method for the separation and purification of four cytochromes c from Azotobacter vinelandii is described. Two new cytochromes c have been purified and are designated cytochromes c(551) and c(555). 2. Additional evidence is presented to establish the dihaem nature of cytochrome c(4). Ultracentrifugation data indicated similar molecular weights for the native and the denatured protein. Cleavage with CNBr yielded seven peptides; the amino acid compositions of the purified peptides were determined. Only one haem peptide was recovered. 3. Cytochromes c(551) and c(555) were characterized as acidic proteins of molecular weights about 12000. The spectral properties, isoelectric points, ;maps' of peptides from CNBr cleavage and amino acid compositions were determined for these two proteins. 4. The spectral properties, isoelectric points, molecular weights, CNBr peptide ;maps', amino acid compositions, relative oxidation-reduction potentials and e.p.r. (electron-paramagnetic-resonance) spectra of the four cytochromes c were compared. Cytochrome c(4) and cytochrome c(551) appear to be distinct proteins. The distinction between cytochromes c(5) and c(555) was not as clear, and our data are inadequate to establish firmly that they are distinct proteins. 5. The dihaem nature of cytochrome c(4) is evident in its e.p.r. spectrum. The e.p.r. spectra are similar to the spectra of mammalian cytochromes c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360247"}
{"pmid": "4360246", "title": "Affinity chromatography of nicotinamide-adenine dinucleotide-linked dehydrogenases on immobilized derivatives of the dinucleotide.", "content": "Affinity chromatography of nicotinamide-adenine dinucleotide-linked dehydrogenases on immobilized derivatives of the dinucleotide. 1. Three established methods for immobilization of ligands through primary amino groups promoted little or no attachment of NAD(+) through the 6-amino group of the adenine residue. Two of these methods (coupling to CNBr-activated agarose and to carbodi-imide-activated carboxylated agarose derivatives) resulted instead in attachment predominantly through the ribosyl residues. Other immobilized derivatives were prepared by azolinkage of NAD(+) (probably through the 8 position of the adenine residue) to a number of different spacer-arm-agarose derivatives. 2. The effectiveness of these derivatives in the affinity chromatography of a variety of NAD-linked dehydrogenases was investigated, applying rigorous criteria to distinguish general or non-specific adsorption effects from truly NAD-specific affinity (bio-affinity). The ribosyl-attached NAD(+) derivatives displayed negligible bio-affinity for any of the NAD-linked dehydrogenases tested. The most effective azo-linked derivative displayed strong bio-affinity for glycer-aldehyde 3-phosphate dehydrogenase, weaker bio-affinity for lactate dehydrogenase and none at all for malate dehydrogenase, although these three enzymes have very similar affinities for soluble NAD(+). Alcohol dehydrogenase and xanthine dehydrogenase were subject to such strong non-specific interactions with the hydrocarbon spacer-arm assembly that any specific affinity was completely eclipsed. 3. It is concluded that, in practice, the general effectiveness of a general ligand may be considerably distorted and attenuated by the nature of the immobilization linkage. However, this attenuation can result in an increase in specific effectiveness, allowing dehydrogenases to be separated from one another in a manner unlikely to be feasible if the general effectiveness of the ligand remained intact. 4. The bio-affinity of the various derivatives for lactate dehydrogenase is correlated with the known structure of the NAD(+)-binding site of this enzyme. Problems associated with the use of immobilized derivatives for enzyme binding and mechanistic studies are briefly discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360246"}
{"pmid": "4360249", "title": "The amino acid sequence of cytochrome c' from Alcaligenes sp. N.C.I.B. 11015.", "content": "The amino acid sequence of cytochrome c' from Alcaligenes sp. N.C.I.B. 11015. The amino acid sequence of the cytochrome c' from Alcaligenes sp. N.C.I.B. 11015 (Iwasaki's ;Pseudomonas denitrificans') has been determined. This organism is the only non-photosynthetic bacterium in which the protein has been found. The protein consists of a single polypeptide chain of 127 residues, with a single haem covalently attached to two cysteines. Unlike normal cytochromes c, the haem attachment site is very close to the C-terminus. The amino acid sequence around the haem attachment site is very similar to that of Chromatium vinosum D cytochrome c'. Detailed evidence for the amino acid sequence of the protein has been deposited as Supplementary Publication SUP 50022 at the British Library (Lending Division), (formerly the National Lending Library for Science and Technology), Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained on the terms given in Biochem. J. (1973) 131, 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360249"}
{"pmid": "4360252", "title": "The b-type cytochromes of bovine heart mitochondria: absorption spectra, enzymatic properties, and distribution in the electron transfer complexes.", "content": "The b-type cytochromes of bovine heart mitochondria: absorption spectra, enzymatic properties, and distribution in the electron transfer complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360252"}
{"pmid": "4360244", "title": "Effects of oxandrolone on plasma lipoproteins and the intravenous fat tolerance in man.", "content": "Effects of oxandrolone on plasma lipoproteins and the intravenous fat tolerance in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360244"}
{"pmid": "4360253", "title": "Cytochrome c involved in the reductive decomposition of organic mercurials. Purification of cytochrome c-I from mercury-resistant Pseudomonas and reactivity of cytochromes c from various kinds of bacteria.", "content": "Cytochrome c involved in the reductive decomposition of organic mercurials. Purification of cytochrome c-I from mercury-resistant Pseudomonas and reactivity of cytochromes c from various kinds of bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360253"}
{"pmid": "4360245", "title": "Letter: IIB or not IIB? Classification of hyperlipoproteinaemias.", "content": "Letter: IIB or not IIB? Classification of hyperlipoproteinaemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360245"}
{"pmid": "4360250", "title": "Purification and properties of a mouse liver plasma-membrane glycoprotein hydrolysing nucleotide pyrophosphate and phosphodiester bonds.", "content": "Purification and properties of a mouse liver plasma-membrane glycoprotein hydrolysing nucleotide pyrophosphate and phosphodiester bonds. 1. A mouse liver plasma-membrane preparation was solubilized in an N-dodecylsarcosinate-Tris buffer, pH7.8, and the proteins and glycoproteins were separated by a rate-zonal centrifugation in sucrose-detergent gradients. 2. A peak of alkaline phosphodiesterase activity which sedimented ahead of the 5'-nucleotidase peak was associated with a major glycoprotein component of the plasma membrane. 3. The phosphodiesterase activity was then purified further by gel filtration and gave a single glycoprotein band after electrophoresis on polyacrylamide gels. The apparent molecular weight of the polypeptide at pH7.4 and 8.9 was 128000-130000 and was independent of the polyacrylamide concentration. Electrophoresis in gels containing deoxycholate showed that the protein band was coincident with phosphodiesterase activity. 4. After two-dimensional immunoelectrophoresis, with agarose containing rabbit anti-(mouse plasma-membrane) antiserum as second dimension, the enzyme showed one component which was also coincident with the phosphodiesterase activity. 5. An amino acid composition of the glycoprotein is presented. Carbohydrate analysis indicated the presence of glucosamine, neutral sugars and sialic acid. 6. The enzyme was also a nucleotide pyrophosphatase, as shown by a similar enrichment during purification of activity towards ATP, NAD(+), UDP-galactose and UDP-N-acetylglucosamine. The phosphodiesterase activity, measured by using dTMP p-nitrophenyl ester as substrate, was competitively inhibited by nucleotide pyrophosphate substrates. The enzyme showed little or no activity towards RNA, cyclic AMP, AMP, ADP and glycerylphosphorylcholine. 7. The significance of this enzyme activity in the plasma membrane is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360250"}
{"pmid": "4360243", "title": "Preparation of tissue fluid of the vessel wall and determination of its lipoproteins.", "content": "Preparation of tissue fluid of the vessel wall and determination of its lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360243"}
{"pmid": "4360255", "title": "Shifts of bacteriochlorophyll and carotenoid absorption bands linked to cytochrome c-555 photooxidation in Chromatium.", "content": "Shifts of bacteriochlorophyll and carotenoid absorption bands linked to cytochrome c-555 photooxidation in Chromatium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360255"}
{"pmid": "4360242", "title": "On the passage-restricting role of acid mucopolysaccharides in the endothelium of pig aortas.", "content": "On the passage-restricting role of acid mucopolysaccharides in the endothelium of pig aortas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360242"}
{"pmid": "4360251", "title": "Immunochemical characterization of proteins from mouse liver plasma membranes.", "content": "Immunochemical characterization of proteins from mouse liver plasma membranes. 1. Antiserum was prepared in rabbits against a purified mouse liver plasma-membrane fraction. 2. The antiserum was made to react with an (125)I-labelled alkaline-EDTA extract of the plasma membranes, and the immunoprecipitate analysed by polyacrylamide-gel electrophoresis. Seven proteins were immunoprecipitated and a single glycoprotein present in the alkaline-EDTA-soluble fraction was found to be a major component. 3. The alkaline-EDTA-soluble fraction was analysed by two-dimensional immunoelectrophoresis and this procedure indicated the presence of six antigenic components. 4. The plasma membranes were also extracted with 1% deoxycholate-1% Triton X-100; 50% of the protein, 80% of the alkaline phosphodiesterase activity and 30% of the 5'-nucleotidase activity were solubilized. 5. Two-dimensional immunoelectrophoresis of the deoxycholate-Triton X-100 extract indicated the presence of six antigens. 6. The relative distribution of the six antigens among the fractions obtained during the extraction procedure was examined immunoelectrophoretically to provide information on their disposition within the membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360251"}
{"pmid": "4360256", "title": "Absorption changes of carotenoids and bacteriochlorophyll in energized chromatophores of Rhodospirillum rubrum.", "content": "Absorption changes of carotenoids and bacteriochlorophyll in energized chromatophores of Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360256"}
{"pmid": "4360257", "title": "Electron paramagnetic resonance signal II in spinach chloroplasts. I. Kinetic analysis for untreated chloroplasts.", "content": "Electron paramagnetic resonance signal II in spinach chloroplasts. I. Kinetic analysis for untreated chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360257"}
{"pmid": "4360258", "title": "Electron paramagnetic resonance signal II in spinach chloroplasts. II. Alternative spectral forms and inhibitor effects on kinetics of signal II in flashing light.", "content": "Electron paramagnetic resonance signal II in spinach chloroplasts. II. Alternative spectral forms and inhibitor effects on kinetics of signal II in flashing light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360258"}
{"pmid": "4360259", "title": "The back reaction in the primary electron transfer couple of photosystem II of photosynthesis.", "content": "The back reaction in the primary electron transfer couple of photosystem II of photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360259"}
{"pmid": "4360260", "title": "C-550 in photosystem II subchloroplast particles.", "content": "C-550 in photosystem II subchloroplast particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360260"}
{"pmid": "4360262", "title": "Inorganic pyrophosphatase and photosynthesis by isolated chloroplasts. II. The controlling influence of orthophosphate.", "content": "Inorganic pyrophosphatase and photosynthesis by isolated chloroplasts. II. The controlling influence of orthophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360262"}
{"pmid": "4360261", "title": "Inorganic pyrophospatase and photosynthesis by isolated chloroplasts. I. Characterisation of chloroplast pyrophosphatase and its relation to the response to exogenous pyrophosphate.", "content": "Inorganic pyrophospatase and photosynthesis by isolated chloroplasts. I. Characterisation of chloroplast pyrophosphatase and its relation to the response to exogenous pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360261"}
{"pmid": "4360268", "title": "Glia of myelination and fat deposit during early myelogenesis.", "content": "Glia of myelination and fat deposit during early myelogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360268"}
{"pmid": "4360269", "title": "Effects of caffeine on radiation-induced phenomena associated with cell-cycle traverse of mammalian cells.", "content": "Effects of caffeine on radiation-induced phenomena associated with cell-cycle traverse of mammalian cells. Caffeine induced a state of G(1) arrest when added to an exponentially growing culture of Chinese hamster cells (line CHO). In addition to its effect on cell-cycle traverse, caffeine ameliorated a number of the responses of cells to ionizing radiation. The duration of the division delay period following X-irradiation of caffeine-treated cells was reduced, and the magnitude of reduction was dependent on caffeine concentration. Cells irradiated during the DNA synthetic phase in the presence of caffeine were delayed less in their exit from S, measured autoradiographically, and the radiation-induced reduction of radioactive thymidine incorporation into DNA was lessened. Cells synchronized by isoleucine deprivation, while being generally less sensitive to the effects of ionizing radiation than mitotically synchronized cells, were equally responsive to the effects of caffeine. The X-ray-induced reduction of phosphorylation of lysine-rich histone F1 was less in caffeine-treated cells than in untreated cells. Finally, survival after irradiation was only slightly reduced in caffeine-treated cells. A possible role of cyclic AMP in cell-cycle traverse of irradiated cells is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360269"}
{"pmid": "4360271", "title": "The metabolic and hemodynamic effects of prolonged bed rest in normal subjects.", "content": "The metabolic and hemodynamic effects of prolonged bed rest in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360271"}
{"pmid": "4360272", "title": "An extralemniscal projection to the centrum medianum and pulvinar of the thalamus.", "content": "An extralemniscal projection to the centrum medianum and pulvinar of the thalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360272"}
{"pmid": "4360276", "title": "Estrogen and progestogen binders in human and rat mammary carcinoma.", "content": "Estrogen and progestogen binders in human and rat mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360276"}
{"pmid": "4360277", "title": "Recovery of the genome of murine sarcoma virus (MSV) after infection of cells with nuclear DNA from MSV transformed non-virus producing cells.", "content": "Recovery of the genome of murine sarcoma virus (MSV) after infection of cells with nuclear DNA from MSV transformed non-virus producing cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360277"}
{"pmid": "4360278", "title": "The relationship between growth rate, labelling index and histological type of human solid tumours.", "content": "The relationship between growth rate, labelling index and histological type of human solid tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360278"}
{"pmid": "4360279", "title": "Postheparin plasma lipase in human subjects. Studies with chylomicrons, very-low density lipoproteins and a fat emulsion.", "content": "Postheparin plasma lipase in human subjects. Studies with chylomicrons, very-low density lipoproteins and a fat emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360279"}
{"pmid": "4360280", "title": "Fine structural studies in myasthenia gravis. I. Muscle fibre lesions.", "content": "Fine structural studies in myasthenia gravis. I. Muscle fibre lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360280"}
{"pmid": "4360281", "title": "A histochemical study of enzymes of carbohydrate metabolism in the rat metanephros.", "content": "A histochemical study of enzymes of carbohydrate metabolism in the rat metanephros.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360281"}
{"pmid": "4360282", "title": "Ultrastructural changes in the rat neurohypophysis in hyper- and hypofunction of adrenal glands.", "content": "Ultrastructural changes in the rat neurohypophysis in hyper- and hypofunction of adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360282"}
{"pmid": "4360283", "title": "Ultrastructural changes in nucleus supraopticus and paraventricularis of rat hypothalamus in hyper- and hypofunction of the adrenals.", "content": "Ultrastructural changes in nucleus supraopticus and paraventricularis of rat hypothalamus in hyper- and hypofunction of the adrenals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360283"}
{"pmid": "4360284", "title": "Cytochemical and ultrastructural features of simian virus 40 transformed macrophages.", "content": "Cytochemical and ultrastructural features of simian virus 40 transformed macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360284"}
{"pmid": "4360285", "title": "Ultrastructural changes of the small intestine in rats during neomycin induced enteropathy.", "content": "Ultrastructural changes of the small intestine in rats during neomycin induced enteropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360285"}
{"pmid": "4360286", "title": "Studies on cytoplasmic tubular inclusions in papilloma and other epithelial tumours.", "content": "Studies on cytoplasmic tubular inclusions in papilloma and other epithelial tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360286"}
{"pmid": "4360287", "title": "Ultrastructure and respiration of isolated heart cells.", "content": "Ultrastructure and respiration of isolated heart cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360287"}
{"pmid": "4360292", "title": "The tumor-promoter phorbol ester (12-O-tetradecanoyl-phorbol-13-acetate), a potent aggregating agent for blood platelets.", "content": "The tumor-promoter phorbol ester (12-O-tetradecanoyl-phorbol-13-acetate), a potent aggregating agent for blood platelets. The phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate, a potent tumor-promoting agent, caused irreversible platelet aggregation when more than 0.02 microM was stirred with human citrated or heparinized platelet-rich plasma (PRP). With washed platelets, 1 nM was effective. The alcohol phorbol, which has little tumor-promoting activity, failed to cause platelet aggregation. With all but low concentrations of phorbol ester, aggregation was succeeded by a rapid phase. The latter was prevented or reduced by enzymes which destroy ADP and by aspirin, was associated with a change in platelet shape, and was presumably due to released ADP. At higher concentrations, only a rapid phase was seen, and these inhibitors were not effective. Low concentrations did not aggregate platelets in PRP containing sufficient EDTA or EGTA to chelate ionized calcium or in PRP from thrombasthenic patients; higher concentrations caused slight aggregation. Both the primary, non-ADP-dependent aggregation and the rapid ADP-dependent aggregation were markedly inhibited by substances which increase cyclic AMP, metabolic inhibitors, and the sulfhydryl inhibitor N-ethylmaleimide. Phorbol ester reduced platelet cyclic AMP only when it had been previously elevated by prostaglandin E(1). 1 microM did not release beta-glucuronidase, lactic dehydrogenase, or inflammatory material from platelets in 4-5 min despite marked aggregation, but liberated all three in 30 min. The possibility is discussed that low phorbol ester concentrations cause primary aggregation by a direct action on platelet actomyosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360292"}
{"pmid": "4360294", "title": "Effect of cytochalasin B and colchicine on alpha-amylase release from rat parotid tissue slices.", "content": "Effect of cytochalasin B and colchicine on alpha-amylase release from rat parotid tissue slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360294"}
{"pmid": "4360295", "title": "The effect of cytochalasin B on pigment dispersion and aggregation in perfused Xenopus laevis tailfin melanophores.", "content": "The effect of cytochalasin B on pigment dispersion and aggregation in perfused Xenopus laevis tailfin melanophores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360295"}
{"pmid": "4360296", "title": "Alkaline phosphatase activity and the regulation of growth in transformed mammalian cells.", "content": "Alkaline phosphatase activity and the regulation of growth in transformed mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360296"}
{"pmid": "4360297", "title": "The localization of enzymatic activities involved in uridine nucleotides reactions in human erythrocytes.", "content": "The localization of enzymatic activities involved in uridine nucleotides reactions in human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360297"}
{"pmid": "4360293", "title": "An improved method for isolating alpha granules and mitochondria from human platelets.", "content": "An improved method for isolating alpha granules and mitochondria from human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360293"}
{"pmid": "4360289", "title": "Erythrocyte adenine phosphoribosyltransferase in the Lesch-Nyhan syndrome.", "content": "Erythrocyte adenine phosphoribosyltransferase in the Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360289"}
{"pmid": "4360298", "title": "Nucleoside diphosphate kinase at the cell surface of neoplastic human cells in culture.", "content": "Nucleoside diphosphate kinase at the cell surface of neoplastic human cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360298"}
{"pmid": "4360299", "title": "Permeability changes during cell fusion.", "content": "Permeability changes during cell fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360299"}
{"pmid": "4360301", "title": "Letter: Does perchlorate enhance brain lesion visibility?", "content": "Letter: Does perchlorate enhance brain lesion visibility?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360301"}
{"pmid": "4360300", "title": "Tumor scanning with 169Yb-citrate.", "content": "Tumor scanning with 169Yb-citrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360300"}
{"pmid": "4360302", "title": "Acetylcholinesterase localization in the giant nerve fiber of the squid.", "content": "Acetylcholinesterase localization in the giant nerve fiber of the squid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360302"}
{"pmid": "4360288", "title": "The study of iodized oil emulsions for indirect lymphography.", "content": "The study of iodized oil emulsions for indirect lymphography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360288"}
{"pmid": "4360303", "title": "Electron microscopic studies of plant tissue cultures infected with the aster yellows disease.", "content": "Electron microscopic studies of plant tissue cultures infected with the aster yellows disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360303"}
{"pmid": "4360290", "title": "Inhibition of Herpes simplex virus replication by camptothecin.", "content": "Inhibition of Herpes simplex virus replication by camptothecin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360290"}
{"pmid": "4360291", "title": "Inhibition of Herpes simplex virus replication by cordycepin.", "content": "Inhibition of Herpes simplex virus replication by cordycepin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360291"}
{"pmid": "4360315", "title": "Swine vesicular disease.", "content": "Swine vesicular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360315"}
{"pmid": "4360316", "title": "Organ culture of bovine teat skin and its application to the study of herpes mammillitis and pseudocowpox infections.", "content": "Organ culture of bovine teat skin and its application to the study of herpes mammillitis and pseudocowpox infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360316"}
{"pmid": "4360318", "title": "The influence of relative humidity on the stability of foot-and-mouth disease virus in aerosols from milk and faecal slurry.", "content": "The influence of relative humidity on the stability of foot-and-mouth disease virus in aerosols from milk and faecal slurry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360318"}
{"pmid": "4360319", "title": "The influence of haemoglobin on the fibrinolytic enzyme system.", "content": "The influence of haemoglobin on the fibrinolytic enzyme system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360319"}
{"pmid": "4360317", "title": "The antiketogenic action of an anabolic steroid administered to ketotic cows.", "content": "The antiketogenic action of an anabolic steroid administered to ketotic cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360317"}
{"pmid": "4360320", "title": "The effects of antiinflammatory drugs on myeloperoxidase mediated iodination in human granulocytes.", "content": "The effects of antiinflammatory drugs on myeloperoxidase mediated iodination in human granulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360320"}
{"pmid": "4360321", "title": "Pharmacology of pressor agents on the systemic circulation.", "content": "Pharmacology of pressor agents on the systemic circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360321"}
{"pmid": "4360322", "title": "The in vivo regulation of the progesterone \"receptor\" in guinea pig uterus: dependence on estrogen and progesterone.", "content": "The in vivo regulation of the progesterone \"receptor\" in guinea pig uterus: dependence on estrogen and progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360322"}
{"pmid": "4360331", "title": "Ultrastructure of Blastocystis hominis.", "content": "Ultrastructure of Blastocystis hominis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360331"}
{"pmid": "4360333", "title": "The effects of niamid and reserpine on the nerve endings of the pineal gland.", "content": "The effects of niamid and reserpine on the nerve endings of the pineal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360333"}
{"pmid": "4360334", "title": "The lymphatic capillaries of the middle ear mucosa in the guinea pig. Ultrastructure and permeability.", "content": "The lymphatic capillaries of the middle ear mucosa in the guinea pig. Ultrastructure and permeability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360334"}
{"pmid": "4360335", "title": "Persistent viral hepatitis.", "content": "Persistent viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360335"}
{"pmid": "4360336", "title": "Fibrous histiocytomas of the orbit.", "content": "Fibrous histiocytomas of the orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360336"}
{"pmid": "4360338", "title": "Prevalence of antibodies to herpesvirus types 1 and 2, arteritis and infectious anemia viral antigens in equine serum.", "content": "Prevalence of antibodies to herpesvirus types 1 and 2, arteritis and infectious anemia viral antigens in equine serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360338"}
{"pmid": "4360337", "title": "Ultrastructure of the synovial membrane of lambs affected with chlamydial polyarthritis.", "content": "Ultrastructure of the synovial membrane of lambs affected with chlamydial polyarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360337"}
{"pmid": "4360339", "title": "Ganglionic and adrenergic effects of 2-phenylquinoline methiodide analogues.", "content": "Ganglionic and adrenergic effects of 2-phenylquinoline methiodide analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360339"}
{"pmid": "4360341", "title": "Pharmacological influences on carbon dioxide-induced amnesia.", "content": "Pharmacological influences on carbon dioxide-induced amnesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360341"}
{"pmid": "4360340", "title": "Cardiovascular effects of Cassella 7657 and its interaction with adenosine, NAD and aminophylline in dogs.", "content": "Cardiovascular effects of Cassella 7657 and its interaction with adenosine, NAD and aminophylline in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360340"}
{"pmid": "4360342", "title": "Fetal consequences of maternal viral infections in pregnancy.", "content": "Fetal consequences of maternal viral infections in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360342"}
{"pmid": "4360344", "title": "Selective, near-total, irreversible inactivation of peripheral pseudocholinesterase and acetylcholinesterase in cats in vivo.", "content": "Selective, near-total, irreversible inactivation of peripheral pseudocholinesterase and acetylcholinesterase in cats in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360344"}
{"pmid": "4360346", "title": "Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in culture.", "content": "Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360346"}
{"pmid": "4360345", "title": "Effects of pyrazole, 4-bromopyrazole and 4-methylpyrazole on mitochondrial function.", "content": "Effects of pyrazole, 4-bromopyrazole and 4-methylpyrazole on mitochondrial function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360345"}
{"pmid": "4360343", "title": "The role of hemodynamic measurements in portosystemic shunt surgery.", "content": "The role of hemodynamic measurements in portosystemic shunt surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360343"}
{"pmid": "4360347", "title": "Carbon tetrachloride induced liver alterations in rats pretreated with N,N'-diphenyl-p-phenylenediamine.", "content": "Carbon tetrachloride induced liver alterations in rats pretreated with N,N'-diphenyl-p-phenylenediamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360347"}
{"pmid": "4360348", "title": "Effects of dichlorodiphenyltrichloroethane (DDT) analogs and polychlorinated biphenyl (PCB) mixtures on 17beta-(3H)estradiol binding to rat uterine receptor.", "content": "Effects of dichlorodiphenyltrichloroethane (DDT) analogs and polychlorinated biphenyl (PCB) mixtures on 17beta-(3H)estradiol binding to rat uterine receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360348"}
{"pmid": "4360349", "title": "Protein iodination with solid state lactoperoxidase.", "content": "Protein iodination with solid state lactoperoxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360349"}
{"pmid": "4360350", "title": "Immunospecificity of nonhistone proteins in chromatin.", "content": "Immunospecificity of nonhistone proteins in chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360350"}
{"pmid": "4360351", "title": "Sequence composition of rat nuclear deoxyribonucleic acid and high molecular weight nuclear ribonucleic acid.", "content": "Sequence composition of rat nuclear deoxyribonucleic acid and high molecular weight nuclear ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360351"}
{"pmid": "4360353", "title": "Calcium-induced phase separations in phosphatidylserine--phosphatidylcholine membranes.", "content": "Calcium-induced phase separations in phosphatidylserine--phosphatidylcholine membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360353"}
{"pmid": "4360354", "title": "Activity of liver alcohol dehydrogenase with various substituents on the amino groups.", "content": "Activity of liver alcohol dehydrogenase with various substituents on the amino groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360354"}
{"pmid": "4360352", "title": "Sequence composition of rat ascites chromosomal ribonucleic acid.", "content": "Sequence composition of rat ascites chromosomal ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360352"}
{"pmid": "4360355", "title": "Inhibition of acetoacetate decarboxylase by ketophosphonates. Structural and dynamic probes of the active site.", "content": "Inhibition of acetoacetate decarboxylase by ketophosphonates. Structural and dynamic probes of the active site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360355"}
{"pmid": "4360363", "title": "Lymphocytosis induced in mice by supernatant fluids of Bordetella pertussis cultures: a histopathological study.", "content": "Lymphocytosis induced in mice by supernatant fluids of Bordetella pertussis cultures: a histopathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360363"}
{"pmid": "4360365", "title": "Interactions of normal and neoplastic fibroblasts with the substratum.", "content": "Interactions of normal and neoplastic fibroblasts with the substratum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360365"}
{"pmid": "4360366", "title": "Dual-precipitation method for lipoprotein quantitation: improvement by membrane ultrafiltration of lipemic samples.", "content": "Dual-precipitation method for lipoprotein quantitation: improvement by membrane ultrafiltration of lipemic samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360366"}
{"pmid": "4360364", "title": "Time lapse studies on the motility of fibroblasts in tissue culture.", "content": "Time lapse studies on the motility of fibroblasts in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360364"}
{"pmid": "4360367", "title": "Letter: The ill-wind in direct analysis of plasma.", "content": "Letter: The ill-wind in direct analysis of plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360367"}
{"pmid": "4360368", "title": "Progress report on long-term oestogen therapy.", "content": "Progress report on long-term oestogen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360368"}
{"pmid": "4360371", "title": "The effect of acute or chronic ether stress on plasma ACTH concentration in the rat.", "content": "The effect of acute or chronic ether stress on plasma ACTH concentration in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360371"}
{"pmid": "4360372", "title": "Effects of hCG, asialo-hCG and the subunits of hCG upon luteinization of monkey granulosa cell cultures.", "content": "Effects of hCG, asialo-hCG and the subunits of hCG upon luteinization of monkey granulosa cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360372"}
{"pmid": "4360373", "title": "ACTH effects on aldosterone production and mitochondrial ultrastructure in adrenal gland cultures.", "content": "ACTH effects on aldosterone production and mitochondrial ultrastructure in adrenal gland cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360373"}
{"pmid": "4360374", "title": "Synergism among growth hormone, ACTH, cortisol and dexamethasone in the hormonal induction of diabetes in rats and the diabetogenic effect of tolbutamide.", "content": "Synergism among growth hormone, ACTH, cortisol and dexamethasone in the hormonal induction of diabetes in rats and the diabetogenic effect of tolbutamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360374"}
{"pmid": "4360375", "title": "The metabolism of cholesterol esters in rat adrenal cell suspensions.", "content": "The metabolism of cholesterol esters in rat adrenal cell suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360375"}
{"pmid": "4360376", "title": "Adrenal progesteerone: factors controlling its secretion.", "content": "Adrenal progesteerone: factors controlling its secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360376"}
{"pmid": "4360379", "title": "Effect of dibutyryl cyclic AMP injected into third ventricle on the thyroid 131-I-iodide accumulation.", "content": "Effect of dibutyryl cyclic AMP injected into third ventricle on the thyroid 131-I-iodide accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360379"}
{"pmid": "4360380", "title": "Extra-lysosomal localization of acid phosphatase in the spinal cord of the rat.", "content": "Extra-lysosomal localization of acid phosphatase in the spinal cord of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360380"}
{"pmid": "4360382", "title": "Somatotopic studies on cerebellar fastigial cells.", "content": "Somatotopic studies on cerebellar fastigial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360382"}
{"pmid": "4360381", "title": "Evidence for GABA as the synaptic transmitter of the inhibitory vestibulo-ocular pathway.", "content": "Evidence for GABA as the synaptic transmitter of the inhibitory vestibulo-ocular pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360381"}
{"pmid": "4360383", "title": "Excitatory and inhibitory responses of neurones of the cerebellar fastigial nucleus.", "content": "Excitatory and inhibitory responses of neurones of the cerebellar fastigial nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360383"}
{"pmid": "4360384", "title": "The pathways responsible for excitation and inhibition of fastigial neurones.", "content": "The pathways responsible for excitation and inhibition of fastigial neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360384"}
{"pmid": "4360385", "title": "Metabolism and isoenzyme alterations in experimental hepatomas.", "content": "Metabolism and isoenzyme alterations in experimental hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360385"}
{"pmid": "4360386", "title": "The suppression of AD-3B mutants by supersuppressors in Neurospora crassa.", "content": "The suppression of AD-3B mutants by supersuppressors in Neurospora crassa. The action of eight suppersuppressors has been tested on 76 ad-3B mutants which were induced by base-pair transition mutagens. Thirteen mutants were found to be suppressible by at least one ssu gene. Most of the suppressible mutants were found to belong to a class in which one would expect to find nonsense mutants (polar complementing or noncomplementing classes, with AT at the mutant site). However, suppression was observed in other classes, including those containing presumed missense mutants. The specificity of the suppressors and the criteria for molecular classification of the mutants are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360386"}
{"pmid": "4360387", "title": "Mosaic analysis of lethal mutations in Drosophila.", "content": "Mosaic analysis of lethal mutations in Drosophila. The effects of various lethal mutations were studied when they were present in the hemizygous state as sectors in genetic mosaics (gynandromorphs) of Drosophila melanogaster. Sixty percent of the lethals studied can survive to adulthood in combination with normal tissue in mosaics, whereas the remainder cause the death of such mosaic animals. Some of the gynandromorph-viable lethals appeared to be locally active, in that they allowed the survival of only those mosaics in which the male tissue was present in the abdomen. The regions affected by these lethals were identified more precisely by analysis of the tissue distributions in the surviving gynandromorphs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360387"}
{"pmid": "4360388", "title": "Dental erosion: progress of erosion measured clinically after various fluoride applications.", "content": "Dental erosion: progress of erosion measured clinically after various fluoride applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360388"}
{"pmid": "4360389", "title": "Hepatic cell carcinoma in a dog.", "content": "Hepatic cell carcinoma in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360389"}
{"pmid": "4360391", "title": "Comparative electrophoretic studies of foot-and-mouth disease virus proteins.", "content": "Comparative electrophoretic studies of foot-and-mouth disease virus proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360391"}
{"pmid": "4360392", "title": "An interfering component of rabies virus which contains RNA.", "content": "An interfering component of rabies virus which contains RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360392"}
{"pmid": "4360390", "title": "A somatic cell approach to the genetic analysis of the laboratory mouse.", "content": "A somatic cell approach to the genetic analysis of the laboratory mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360390"}
{"pmid": "4360394", "title": "Electron microscopy and infectivity studies of the action of dimethylsulphoxide on two strains of tobacco mosaic virus.", "content": "Electron microscopy and infectivity studies of the action of dimethylsulphoxide on two strains of tobacco mosaic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360394"}
{"pmid": "4360393", "title": "Comparative electrophoretic analysis of the virus proteins of four rhabdoviruses.", "content": "Comparative electrophoretic analysis of the virus proteins of four rhabdoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360393"}
{"pmid": "4360396", "title": "Refractory state of cells to interferon induction.", "content": "Refractory state of cells to interferon induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360396"}
{"pmid": "4360395", "title": "Heterogeneity of simian virus 40 populations: virus particles containing one or two virus DNA molecules?", "content": "Heterogeneity of simian virus 40 populations: virus particles containing one or two virus DNA molecules?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360395"}
{"pmid": "4360398", "title": "Controlled trial of combinations of hydroxocobalamin-cystine and riboflavine-cystine, in Nigerian ataxic neuropathy.", "content": "Controlled trial of combinations of hydroxocobalamin-cystine and riboflavine-cystine, in Nigerian ataxic neuropathy. Chronic cyanide intoxication of dietary origin and riboflavine deficiency are believed to be major aetiological factors in Nigerian tropical ataxic neuropathy. The results are presented of a double-blind controlled therapeutic trial of combinations of large doses of hydroxocobalamin and cystine as cyanide binding agents together with riboflavine or placebos in Nigerian patients suffering from the tropical ataxic neuropathy. No clinical benefit was demonstrable with any of the treatments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360398"}
{"pmid": "4360399", "title": "Disturbances in the voluntary recruitment order of anterior tibial motor units in spastic paraparesis upon fatigue.", "content": "Disturbances in the voluntary recruitment order of anterior tibial motor units in spastic paraparesis upon fatigue. The recruitment order of motor units in the tibialis anterior muscle upon fatigue of tonic voluntary contraction was studied in 20 patients with severe spastic paraparesis. An electromyographic technique for secure identification of single motor units was used. Before fatigue the recruitment order is stable and low-frequency units are recruited before high-frequency units; this recruitment pattern agrees with that in normal voluntary activity. When fatigue appears, however, the recruitment order becomes indefinite and high-frequency units can be recruited before low-frequency units; this recruitment pattern agrees with that in normal phasic voluntary activity. Finally, all voluntary activation power disappears, even in the case of units which have never been active. Contraction ability and original recruitment order are restored upon rest but also upon tonic reflex support of the voluntary drive. Whether the fatigue reaction may be due to insufficient gamma motoneurone innervation and whether it is related to spasticity are discussed. The practical physiotherapeutic implications are reviewed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360399"}
{"pmid": "4360397", "title": "Alterations in the surface glycoproteins of chicken erythrocytes following transformation with erythroblastosis strain R virus.", "content": "Alterations in the surface glycoproteins of chicken erythrocytes following transformation with erythroblastosis strain R virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360397"}
{"pmid": "4360400", "title": "Motor unit estimations in small muscles of the hand.", "content": "Motor unit estimations in small muscles of the hand. A quantal method has been employed to determine the numbers of functioning motor units in small muscles of the hand. In healthy subjects below the age of 60 years the mean number of hypothenar motor units was 380 ± 79 and the mean number of thenar units innervated by the median nerve was 340 ± 87. In older subjects there was a progressive reduction in the numbers of functioning units in both muscle groups; in some of these subjects the population of motor units in the extensor digitorum brevis was also estimated for comparison. A study was also performed on patients diagnosed as having generalized denervating diseases or with lesions of peripheral nerves and cervical roots; in every instance the number of functioning motor units was markedly reduced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360400"}
{"pmid": "4360402", "title": "Mixed or immune complex cryoglobulinaemia and neuropathy.", "content": "Mixed or immune complex cryoglobulinaemia and neuropathy. Three patients with peripheral neuropathy and mixed or immune complex cryoglobulinaemia are reported. The significance of mixed cryoglobulinaemia and the pathogenesis of the peripheral neuropathy are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360402"}
{"pmid": "4360401", "title": "Hypertrophic mononeuropathy.", "content": "Hypertrophic mononeuropathy. A case of hypertrophic mononeuropathy is described in a 19-year-old female. The entity is very rare as only three previous cases have been reported. The light and electron-microscope appearances resemble those of progressive hypertrophic polyneuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360401"}
{"pmid": "4360407", "title": "Response of Escherichia coli to ethyl methanesulfonate: influence of growth phase and repair ability on survival and mutagenesis.", "content": "Response of Escherichia coli to ethyl methanesulfonate: influence of growth phase and repair ability on survival and mutagenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360407"}
{"pmid": "4360408", "title": "Chemically induced mutation of L-5178Y mouse leukemia cells from asparagine-dependence to asparagine-independence.", "content": "Chemically induced mutation of L-5178Y mouse leukemia cells from asparagine-dependence to asparagine-independence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360408"}
{"pmid": "4360409", "title": "Humoral transmission of sleep. 8. Effects of the \"sleep factor delta\" on cerebral, motor and visceral activities.", "content": "Humoral transmission of sleep. 8. Effects of the \"sleep factor delta\" on cerebral, motor and visceral activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360409"}
{"pmid": "4360410", "title": "Theophylline potentiation of in vitro effects of ACTH and catecholamines in rabbit adipose tissue.", "content": "Theophylline potentiation of in vitro effects of ACTH and catecholamines in rabbit adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360410"}
{"pmid": "4360411", "title": "Effect of coal and quartz dust on ciliary activity in the respiratory tract.", "content": "Effect of coal and quartz dust on ciliary activity in the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360411"}
{"pmid": "4360406", "title": "Cross-linking of collagen. Hydrogen abstraction studies on model compounds.", "content": "Cross-linking of collagen. Hydrogen abstraction studies on model compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360406"}
{"pmid": "4360414", "title": "Identifying the organism in vulvovaginal infections.", "content": "Identifying the organism in vulvovaginal infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360414"}
{"pmid": "4360417", "title": "Reye's syndrome: isolation of parainfluenza virus. Report of three cases.", "content": "Reye's syndrome: isolation of parainfluenza virus. Report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360417"}
{"pmid": "4360416", "title": "Senescence and death of the conidiogenous cell in Stemphylium botryosum Wallroth.", "content": "Senescence and death of the conidiogenous cell in Stemphylium botryosum Wallroth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360416"}
{"pmid": "4360418", "title": "Cerebellar toxic effects from nitrofurantoin.", "content": "Cerebellar toxic effects from nitrofurantoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360418"}
{"pmid": "4360415", "title": "Infection in the severely traumatized patient.", "content": "Infection in the severely traumatized patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360415"}
{"pmid": "4360419", "title": "Adenosine 3',5'-monophosphate in cerebrospinal fluid. Effect of drugs and neurologic disease.", "content": "Adenosine 3',5'-monophosphate in cerebrospinal fluid. Effect of drugs and neurologic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360419"}
{"pmid": "4360420", "title": "Hexachlorophene neuropathy.", "content": "Hexachlorophene neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360420"}
{"pmid": "4360421", "title": "A summary and evaluation of spin labels used as probes for biological membrane structure.", "content": "A summary and evaluation of spin labels used as probes for biological membrane structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360421"}
{"pmid": "4360422", "title": "Membrane fusion.", "content": "Membrane fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360422"}
{"pmid": "4360423", "title": "Frog lactate dehydrogenase: kinetics at physiological enzyme levels.", "content": "Frog lactate dehydrogenase: kinetics at physiological enzyme levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360423"}
{"pmid": "4360424", "title": "Bilirubin: a potent inhibitor of NAD+-linked isocitrate dehydrogenase.", "content": "Bilirubin: a potent inhibitor of NAD+-linked isocitrate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360424"}
{"pmid": "4360425", "title": "One-electron transfer reactions in biochemical systems. VII. Two types of electron outlets in milk xanthine oxidase.", "content": "One-electron transfer reactions in biochemical systems. VII. Two types of electron outlets in milk xanthine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360425"}
{"pmid": "4360426", "title": "One-electron transfer reactions in biochemical systems. 8. Kinetic study of superoxide dismutase.", "content": "One-electron transfer reactions in biochemical systems. 8. Kinetic study of superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360426"}
{"pmid": "4360427", "title": "Conversion of glycogen synthetase D of rat liver to a form that resembles synthetase D of skeletal muscle.", "content": "Conversion of glycogen synthetase D of rat liver to a form that resembles synthetase D of skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360427"}
{"pmid": "4360429", "title": "On the nature of the acceleration of the methanesulfonylation of acetylcholinesterase by tetraethylammonium.", "content": "On the nature of the acceleration of the methanesulfonylation of acetylcholinesterase by tetraethylammonium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360429"}
{"pmid": "4360428", "title": "Purification and characterization of a protein kinase in Tetrahymena cilia.", "content": "Purification and characterization of a protein kinase in Tetrahymena cilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360428"}
{"pmid": "4360430", "title": "Kinetics of the reaction of human renin with natural substrates and tetradecapeptide substrate.", "content": "Kinetics of the reaction of human renin with natural substrates and tetradecapeptide substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360430"}
{"pmid": "4360431", "title": "Effect of free magnesium and salts on the inorganic pyrophosphatase purified from a slightly halophilic Vibrio alginolyticus.", "content": "Effect of free magnesium and salts on the inorganic pyrophosphatase purified from a slightly halophilic Vibrio alginolyticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360431"}
{"pmid": "4360432", "title": "A spin label investigation of some model membrane systems.", "content": "A spin label investigation of some model membrane systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360432"}
{"pmid": "4360433", "title": "Mass spectra of trimethylsilyl derivatives of homogeneous cerebrosides (monoglycosylceramides).", "content": "Mass spectra of trimethylsilyl derivatives of homogeneous cerebrosides (monoglycosylceramides).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360433"}
{"pmid": "4360435", "title": "Muscular dystrophy in childhood.", "content": "Muscular dystrophy in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360435"}
{"pmid": "4360434", "title": "Iron transport by phospholipids in a two phase system containing water and n-pentanol.", "content": "Iron transport by phospholipids in a two phase system containing water and n-pentanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360434"}
{"pmid": "4360441", "title": "Effects of quantal unit latency on statistics of Poisson and binomial neurotransmitter release mechanisms.", "content": "Effects of quantal unit latency on statistics of Poisson and binomial neurotransmitter release mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360441"}
{"pmid": "4360442", "title": "Surgery of bilateral Wilms tumors: the role of renal transplantation.", "content": "Surgery of bilateral Wilms tumors: the role of renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360442"}
{"pmid": "4360443", "title": "Congenital solitary kidney: a review of 74 cases.", "content": "Congenital solitary kidney: a review of 74 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360443"}
{"pmid": "4360444", "title": "Plasma renin and aldosterone after renal transplantation.", "content": "Plasma renin and aldosterone after renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360444"}
{"pmid": "4360445", "title": "Adenylate cyclase activity in rat submandibular gland during postnatal development.", "content": "Adenylate cyclase activity in rat submandibular gland during postnatal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360445"}
{"pmid": "4360447", "title": "Further characterization of mono and diglyceride lipases in rat tissues.", "content": "Further characterization of mono and diglyceride lipases in rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360447"}
{"pmid": "4360446", "title": "The effects of silica dust and alveolar macrophages on lung fibroblasts grown in vitro.", "content": "The effects of silica dust and alveolar macrophages on lung fibroblasts grown in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360446"}
{"pmid": "4360452", "title": "The interaction between Entamoeba histolytica and Schistosoma mansoni infections in mice.", "content": "The interaction between Entamoeba histolytica and Schistosoma mansoni infections in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360452"}
{"pmid": "4360453", "title": "Indirect immunofluorescent staining of trophozoites of Entamoeba histolytica.", "content": "Indirect immunofluorescent staining of trophozoites of Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360453"}
{"pmid": "4360454", "title": "Canine malignant mammary tumors. 3. Special types of carcinomas, malignant mixed tumors.", "content": "Canine malignant mammary tumors. 3. Special types of carcinomas, malignant mixed tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360454"}
{"pmid": "4360455", "title": "Permanent mixed-field polyagglutinability (PMFP). I. Serological observations.", "content": "Permanent mixed-field polyagglutinability (PMFP). I. Serological observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360455"}
{"pmid": "4360449", "title": "A possible direct action of ACTH on nerve and muscle.", "content": "A possible direct action of ACTH on nerve and muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360449"}
{"pmid": "4360456", "title": "Permanent mixed-field polyagglutinability (PMFP). II. Hematological, biophysical and biochemical observations.", "content": "Permanent mixed-field polyagglutinability (PMFP). II. Hematological, biophysical and biochemical observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360456"}
{"pmid": "4360459", "title": "Action of cyclic AMP on pigment donation between mammalian melanocytes and keratinocytes.", "content": "Action of cyclic AMP on pigment donation between mammalian melanocytes and keratinocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360459"}
{"pmid": "4360458", "title": "Molecular biology of pigment cells. Molecular controls in mammalian pigmentation.", "content": "Molecular biology of pigment cells. Molecular controls in mammalian pigmentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360458"}
{"pmid": "4360462", "title": "Effects of calcitonin on osteoclasts in vivo. An ultrastructural and histochemical study.", "content": "Effects of calcitonin on osteoclasts in vivo. An ultrastructural and histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360462"}
{"pmid": "4360457", "title": "Ultrastructure and cell biology of pigment cells. Intracellular dynamics and the fine structure of melanocytes with special reference to the effects of MSH and cyclic AMP on microtubules and 10-nm filaments.", "content": "Ultrastructure and cell biology of pigment cells. Intracellular dynamics and the fine structure of melanocytes with special reference to the effects of MSH and cyclic AMP on microtubules and 10-nm filaments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360457"}
{"pmid": "4360461", "title": "On the fine structure of the Octopus iris.", "content": "On the fine structure of the Octopus iris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360461"}
{"pmid": "4360465", "title": "Association of renal allograft rejection with virus infections.", "content": "Association of renal allograft rejection with virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360465"}
{"pmid": "4360463", "title": "Fine structural studies of rat adrenal cortices following prostaglandin administration.", "content": "Fine structural studies of rat adrenal cortices following prostaglandin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360463"}
{"pmid": "4360468", "title": "Muscle spindle distribution in the masticatory muscle of the squirrel monkey (Saimiri sciurea).", "content": "Muscle spindle distribution in the masticatory muscle of the squirrel monkey (Saimiri sciurea).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360468"}
{"pmid": "4360469", "title": "Arsenical polyneuropathy-a clinical study.", "content": "Arsenical polyneuropathy-a clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360469"}
{"pmid": "4360470", "title": "Progesterone binding in the immature rabbit and guinea pig uterus.", "content": "Progesterone binding in the immature rabbit and guinea pig uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360470"}
{"pmid": "4360471", "title": "In vivo action of vinblastine on thyroid ultrastructure and hormone secretion.", "content": "In vivo action of vinblastine on thyroid ultrastructure and hormone secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360471"}
{"pmid": "4360472", "title": "Studies on cyclic nucleotides in the adrenal gland. IV. Effect of ACTH on cyclic nucleotides-dependent protein kinases in the adrenal gland.", "content": "Studies on cyclic nucleotides in the adrenal gland. IV. Effect of ACTH on cyclic nucleotides-dependent protein kinases in the adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360472"}
{"pmid": "4360464", "title": "Fine structure and innervation of the avian adrenal gland. V. Innervation of interrenal cells.", "content": "Fine structure and innervation of the avian adrenal gland. V. Innervation of interrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360464"}
{"pmid": "4360473", "title": "Effect of hypophysectomy and adrenalectomy on glucagon and insulin concentration.", "content": "Effect of hypophysectomy and adrenalectomy on glucagon and insulin concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360473"}
{"pmid": "4360474", "title": "Effect of ACTH and camp on human adrenocortical growth and function in vitro.", "content": "Effect of ACTH and camp on human adrenocortical growth and function in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360474"}
{"pmid": "4360476", "title": "Androgen receptors in mouse kidney: a study of male, female and androgen-insensitive (tfm-y) mice.", "content": "Androgen receptors in mouse kidney: a study of male, female and androgen-insensitive (tfm-y) mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360476"}
{"pmid": "4360475", "title": "Hormonal control of adrenal RNA polymerase activities.", "content": "Hormonal control of adrenal RNA polymerase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360475"}
{"pmid": "4360467", "title": "Glycogen metabolism and its control by norepinephrine in cardiac Purkinje fibers.", "content": "Glycogen metabolism and its control by norepinephrine in cardiac Purkinje fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360467"}
{"pmid": "4360477", "title": "Studies on the nature of the hypothalamic estradiol-concentrating mechanism in the male and female rat.", "content": "Studies on the nature of the hypothalamic estradiol-concentrating mechanism in the male and female rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360477"}
{"pmid": "4360478", "title": "Oral contraceptives: ethinyl estradiol binds with higher affinity than mestranol to macromolecules from the sites of anti-fertility action.", "content": "Oral contraceptives: ethinyl estradiol binds with higher affinity than mestranol to macromolecules from the sites of anti-fertility action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360478"}
{"pmid": "4360479", "title": "In vitro arterial perfusion of the dog adrenal.", "content": "In vitro arterial perfusion of the dog adrenal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360479"}
{"pmid": "4360480", "title": "Inhibition of luteinization of transplanted rat ovarian follicles by polyphloretin phosphate.", "content": "Inhibition of luteinization of transplanted rat ovarian follicles by polyphloretin phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360480"}
{"pmid": "4360482", "title": "Purification and immunochemical studies of the protein-bound J substance from cattle serum.", "content": "Purification and immunochemical studies of the protein-bound J substance from cattle serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360482"}
{"pmid": "4360484", "title": "Studies on the effect of cyclic-AMP on the ingibition of lipolysis by insulin & some oral hypoglycaemic agents.", "content": "Studies on the effect of cyclic-AMP on the ingibition of lipolysis by insulin & some oral hypoglycaemic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360484"}
{"pmid": "4360483", "title": "Carcinoembryonic antigen (CEA) in non digestive cancerous and normal tissues.", "content": "Carcinoembryonic antigen (CEA) in non digestive cancerous and normal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360483"}
{"pmid": "4360481", "title": "Estradiol receptor in rat testis.", "content": "Estradiol receptor in rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360481"}
{"pmid": "4360485", "title": "Viruses associated with clinical cases with special reference to poliomyelitis epidemic of 1971 in and around Chandigarh (Northern India).", "content": "Viruses associated with clinical cases with special reference to poliomyelitis epidemic of 1971 in and around Chandigarh (Northern India).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360485"}
{"pmid": "4360466", "title": "In vivo effects of phytohaemoagglutinin on NAD-glycohydrolase activity and histological features of spleen, thymus and liver in the rat.", "content": "In vivo effects of phytohaemoagglutinin on NAD-glycohydrolase activity and histological features of spleen, thymus and liver in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360466"}
{"pmid": "4360487", "title": "Chemotaxis of polymorphonuclear leukocytes in corneal inflammation: tissue injury in herpes simplex virus infection.", "content": "Chemotaxis of polymorphonuclear leukocytes in corneal inflammation: tissue injury in herpes simplex virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360487"}
{"pmid": "4360488", "title": "Effects of isoproterenol and cyclic AMP derivatives on cell division in cultured rat lenses.", "content": "Effects of isoproterenol and cyclic AMP derivatives on cell division in cultured rat lenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360488"}
{"pmid": "4360486", "title": "Changes in the contents of cholesterol and phosphatases in the lungs of rats exposed to mica dust.", "content": "Changes in the contents of cholesterol and phosphatases in the lungs of rats exposed to mica dust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360486"}
{"pmid": "4360489", "title": "Multiple sclerosis: an overview, with some observations on the spinal fluid protein.", "content": "Multiple sclerosis: an overview, with some observations on the spinal fluid protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360489"}
{"pmid": "4360491", "title": "Procarbazine hydrochloride in the treatment of brain tumors. Phase 2 study.", "content": "Procarbazine hydrochloride in the treatment of brain tumors. Phase 2 study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360491"}
{"pmid": "4360492", "title": "A technique for relief of motor and sensory deficits occurring after anterior ulnar transposition. Technical note.", "content": "A technique for relief of motor and sensory deficits occurring after anterior ulnar transposition. Technical note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360492"}
{"pmid": "4360493", "title": "Chromosome breakage in Drosophila melanogaster induced by a monofunctional alkylating agent (EMS).", "content": "Chromosome breakage in Drosophila melanogaster induced by a monofunctional alkylating agent (EMS).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360493"}
{"pmid": "4360494", "title": "Investigation of the antifungal activity of the Nelex solution.", "content": "Investigation of the antifungal activity of the Nelex solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360494"}
{"pmid": "4360496", "title": "Letter: Cyclic AMP and corticosteroids.", "content": "Letter: Cyclic AMP and corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360496"}
{"pmid": "4360495", "title": "Letter: Possible neuropathy from methyl N-butyl ketone.", "content": "Letter: Possible neuropathy from methyl N-butyl ketone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360495"}
{"pmid": "4360498", "title": "Letter: Abdominal pain in hyperlipoproteinemia.", "content": "Letter: Abdominal pain in hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360498"}
{"pmid": "4360497", "title": "Letter: EBV and American Burkitt's lymphoma.", "content": "Letter: EBV and American Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360497"}
{"pmid": "4360504", "title": "Neurologic manifestations in patients with mixed cryoglobulinemia.", "content": "Neurologic manifestations in patients with mixed cryoglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360504"}
{"pmid": "4360508", "title": "Extra-articular pigmented villonodular synovitis affecting bone. The role of angiography as an aid in its differentiation from similar bone-destroying conditions.", "content": "Extra-articular pigmented villonodular synovitis affecting bone. The role of angiography as an aid in its differentiation from similar bone-destroying conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360508"}
{"pmid": "4360502", "title": "Spinal cord pathways involved in tourniquet stimulation of ACTH secretion.", "content": "Spinal cord pathways involved in tourniquet stimulation of ACTH secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360502"}
{"pmid": "4360499", "title": "Effects of cortical spreading depression on multiunit activity in the preoptic area and hypothalamus of the female rat.", "content": "Effects of cortical spreading depression on multiunit activity in the preoptic area and hypothalamus of the female rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360499"}
{"pmid": "4360503", "title": "Influence of 6-hydroxydopamine on hypothalamic control of prolactin and ACTH secretion in the teleost fish, Tilapia mossambica.", "content": "Influence of 6-hydroxydopamine on hypothalamic control of prolactin and ACTH secretion in the teleost fish, Tilapia mossambica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360503"}
{"pmid": "4360501", "title": "Physiological regulation of tissue-CRF.", "content": "Physiological regulation of tissue-CRF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360501"}
{"pmid": "4360516", "title": "A selective medium for the isolation of Corynebacterium pyogenes.", "content": "A selective medium for the isolation of Corynebacterium pyogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360516"}
{"pmid": "4360500", "title": "ACTH release in rats after removal of the medial hypothalamus.", "content": "ACTH release in rats after removal of the medial hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360500"}
{"pmid": "4360490", "title": "Detection of cyclic AMP in parotid saliva of normal individuals.", "content": "Detection of cyclic AMP in parotid saliva of normal individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360490"}
{"pmid": "4360522", "title": "The effect of p,p'-DDT (Dicophane) and its main metabolites on the respiration of rat liver mitochondria.", "content": "The effect of p,p'-DDT (Dicophane) and its main metabolites on the respiration of rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360522"}
{"pmid": "4360524", "title": "Hypertension: a disease of abnormal circulatory control.", "content": "Hypertension: a disease of abnormal circulatory control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360524"}
{"pmid": "4360525", "title": "A catecholamine secreting retroperitoneal glomangioma. A case report.", "content": "A catecholamine secreting retroperitoneal glomangioma. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360525"}
{"pmid": "4360528", "title": "The effect of photosensitizing dyes on the 3H-thymidine incorporation of cells grown in vitro.", "content": "The effect of photosensitizing dyes on the 3H-thymidine incorporation of cells grown in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360528"}
{"pmid": "4360527", "title": "Enhancement of senescence in low passage human embryonic lung cells by an agent extracted from phase 3 cells.", "content": "Enhancement of senescence in low passage human embryonic lung cells by an agent extracted from phase 3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360527"}
{"pmid": "4360526", "title": "Stepwise accumulation of autoregulated enzyme activities during the cell cycle of the eucaryote Chlorella.", "content": "Stepwise accumulation of autoregulated enzyme activities during the cell cycle of the eucaryote Chlorella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360526"}
{"pmid": "4360529", "title": "Myogenic cells derived from murine sarcoma induced mouse tumours: DNA synthesis and the effects of simian virus 40 infection.", "content": "Myogenic cells derived from murine sarcoma induced mouse tumours: DNA synthesis and the effects of simian virus 40 infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360529"}
{"pmid": "4360530", "title": "Activation of nuclear chromatin and the release from contact-inhibition of 3T3 cells.", "content": "Activation of nuclear chromatin and the release from contact-inhibition of 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360530"}
{"pmid": "4360531", "title": "Maturation-stimulation effect of brain extract and dibutyryl cyclic AMP on dissociated embryonic brain cells in culture.", "content": "Maturation-stimulation effect of brain extract and dibutyryl cyclic AMP on dissociated embryonic brain cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360531"}
{"pmid": "4360532", "title": "Citric acid-sonication method for the isolation of nucleoli.", "content": "Citric acid-sonication method for the isolation of nucleoli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360532"}
{"pmid": "4360533", "title": "Deoxyribonuclease in sea urchin embryos. Comparison of the activity present in developing embryos, in nuclei, and in mitochondria.", "content": "Deoxyribonuclease in sea urchin embryos. Comparison of the activity present in developing embryos, in nuclei, and in mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360533"}
{"pmid": "4360534", "title": "Differential sensitivity of antigen- and mitogen-stimulated human leukocytes to prolonged inhibition of potassium transport.", "content": "Differential sensitivity of antigen- and mitogen-stimulated human leukocytes to prolonged inhibition of potassium transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360534"}
{"pmid": "4360536", "title": "Nature of the specificity of alcohol coupling to L-alanine transport into isolated membrane vesicles of a marine pseudomonad.", "content": "Nature of the specificity of alcohol coupling to L-alanine transport into isolated membrane vesicles of a marine pseudomonad. Ethanol stimulated the uptake of l-alanine into isolated membrane vesicles of a marine pseudomonad at a rate and to an extent comparable with that obtained with reduced nicotinamide adenine dinucleotide (NADH) or the artificial electron donor ascorbate-N, N, N', N'-tetramethyl-p-phenylenediamine (ascorbate-TMPD). Methanol and branched-chain alcohols had little or no capacity to energize transport. No quantitative relationship was found between the ability of a compound to induce oxygen uptake and to energize transport, since with ethanol initial rates of oxygen uptake were approximately 4% of that obtained with NADH or ascorbate-TMPD. Cytochrome analysis revealed that NADH and ethanol reduced cytochromes b and c, whereas ascorbate-TMPD coupled primarily at the level of cytochrome c. Approximately 25% of the cytochromes reduced by dithionite were reducible by ethanol. Ethanol reduction of both cytochromes b and c was prevented by 2-heptyl-4-hydroxyquinoline-N-oxide, p-chloromercuribenzoate, N-ethylmaleimide, and iodoacetate. The ethanol- and NADH-energized transport systems for l-alanine were subject to quantitatively similar inhibition by cyanide, 2-heptyl-4-hydroxyquinoline-N-oxide, 2, 4-dinitrophenol, and the sulfhydryl reagents p-chloromercuribenzoate, N-ethylmaleimide, and iodoacetate. In contrast, for ascorbate-TMPD-driven transport, only cyanide and 2, 4-dinitrophenol remained fully effective as inhibitors, p-chloromercuribenzoate was only half as effective, and the other compounds stimulated transport. Inhibition of ethanol oxidation strikingly paralleled the inhibition of ethanol-driven transport for each of the inhibitors, including 2, 4-dinitrophenol. Marked differences between inhibition of oxygen uptake and inhibition of transport were observed when NADH or ascorbate-TMPD were the electron donors. The data indicate that only a small proportion of the respiratory chain complexes in the membrane vesicles are involved in transport and these are efficiently coupled to ethanol oxidation. The results also suggest that when 2, 4-dinitrophenol inhibits transport it is not acting as an uncoupling agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360536"}
{"pmid": "4360537", "title": "Specific electron donor-energized transport of alpha-aminoisobutyric acid and K+ into intact cells of a marine pseudomonad.", "content": "Specific electron donor-energized transport of alpha-aminoisobutyric acid and K+ into intact cells of a marine pseudomonad. The transport of alpha-aminoisobutyric acid and K(+) into K(+)-depleted cells of a marine pseudomonad (ATCC 19855) was stimulated strongly by ethanol, reduced nicotinamide adenine dinucleotide (NADH), and ascorbate-reduced N, N, N', N'-tetramethyl-p-phenylenediamine. In the presence of the quinone inhibitor 2-heptyl-4-hydroxyquinoline-N-oxide, only ascorbate-reduced N, N, N', N'-tetramethyl-p-phenylenediamine was active. Primary and secondary, but not tertiary, alcohols from ethanol to n-amyl alcohol stimulated both alpha-aminoisobutyric acid and K(+) transport and were oxidized by the cells. Malate and succinate, which were oxidized rapidly by the cells, had little or no capacity to energize the transport of alpha-aminoisobutyric acid into K(+)-depleted cells but were partially effective in promoting K(+) uptake. Ethanol stimulated the transport of alpha-aminoisobutyric acid into K(+)-preloaded cells. The transport of both alpha-aminoisobutyric acid and K(+) was inhibited 20% by iodoacetate, 85% by N-ethylmaleimide, and 90 to 100% by both NaCN and p-chloromercuribenzoate. The addition of Na(3)Fe(CN)(6) permitted the ethanol-induced transport of alpha-aminoisobutyric acid into K(+)-preloaded cells in the presence of NaCN, but little or no uptake of alpha-aminoisobutyric acid or of K(+) into K(+)-depleted cells under the same conditions. The transport of alpha-aminoisobutyric acid into K(+)-depleted cells required both K(+) and an electron donor. The oxidation of NADH and ethanol by K(+)-depleted cells was stimulated strongly by K(+). Parallels between these studies and those with membrane vesicles show that results with membrane vesicles of the marine pseudomonad have physiological significance for the intact cells. The results support the conclusion that the energy for the active transport of both alpha-aminoisobutyric acid and K(+) into cells of this organism is provided by electron flow through a region of the respiratory chain lying between cytochrome c and O(2).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360537"}
{"pmid": "4360538", "title": "De novo purine synthesis in vegetative cells and myxospores of Myxococcus xanthus.", "content": "De novo purine synthesis in vegetative cells and myxospores of Myxococcus xanthus. This study was designed to determine whether vegetative cells and myxospores of Myxococcus xanthus were capable of classical de novo purine biosynthesis. To answer this question, vegetative and myxospore extracts of M. xanthus FBa were tested for their ability to synthesize the second de novo intermediate, 5'-phosphoribosylglycinamide, from beginning precursors either by way of phosphoribosyl-pyrophosphate amido transferase (EC 2.4.2.14) or ribose-5-phosphate amino transferase. Both the amido and amino transferase routes occurred in both types of extracts, and both enzymes appear to be present at about the same level (per milligram of protein) in vegetative cells, myxospores, and in a bacterial prototype, Salmonella typhimurium. The dose response of the vegetative and myxospore forms of both enzymes towards adenosine 5'-monophosphate (AMP) and guanosine 5'-monophosphate (GMP) suggests that the allosteric structure of both enzymes is changed little by sporulation. Both enzymes were inhibited to varying degrees by a variety of purine nucleotides besides AMP, GMP, and 3':5' cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360538"}
{"pmid": "4360540", "title": "Fatty acid degradation in Escherichia coli: requirement of cyclic adenosine monophosphate and cyclic adenosine monophosphate receptor protein for enzyme synthesis.", "content": "Fatty acid degradation in Escherichia coli: requirement of cyclic adenosine monophosphate and cyclic adenosine monophosphate receptor protein for enzyme synthesis. The strong repression of inducible synthesis of the enzymes of fatty acid degradation by glucose can be partially relieved by the addition of cyclic adenosine 3',5' monophosphate (cyclic AMP) to the growth medium. This reversal of the glucose effect by cyclic AMP is not observed in a mutant (K29) that is unable to grow on fatty acids as sole carbon source and that was found to synthesize low levels of several enzymes specified by the fad regulon. In a revertant selected for the ability to grow on oleate these effects are concomitantly relieved. By both genetic (co-transduction of the mutation with the strA locus) and biochemical experiments (an extract of the mutant strain does not show the cyclic AMP-dependent stimulation of the deoxyribonucleic acid-directed in vitro synthesis of the enzymes of the gal operon), it is demonstrated that the mutant lacks functional cyclic AMP receptor protein (CR protein). It is concluded that, like many other inducible enzyme systems, expression of the enzymes of the fad system requires cyclic AMP and the CR protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360540"}
{"pmid": "4360541", "title": "Isolation and characterization of temperature-sensitive mutants of host-dependent Bdellovibrio bacteriovorus 109D.", "content": "Isolation and characterization of temperature-sensitive mutants of host-dependent Bdellovibrio bacteriovorus 109D. A variety of temperature-sensitive mutants of host-dependent Bdellovibrio bacteriovorus 109D were selected after ethyl methane sulfonate mutagenesis. Mutants that demonstrated plaque-forming ability reversion frequencies of 10(-8) to 10(-9) were chosen for further study. Representatives of these mutants were then characterized by phase-contrast and electron microscopy, temperature-shifted one-step growth experiments, attachment kinetics, and macromolecular capabilities. Representative mutants demonstrate various types of blockage corresponding to the previously described morphological stages of Bdellovibrio predatious life cycle, i.e., attachment blockage (109D153), penetration blockage (109D3 and 109D48), and blockage of intracellular growth (109D4 and 109D152). The time of release from temperature repression for the mutant classes was found to correspond to the apparent morphological stage of blockage via temperature-shifted, one-step growth experiments. Mutants characterized as exhibiting blockage in the penetration or intracellular stages of the infection cycle exhibited, at the permissive and nonpermissive temperatures, kinetics of attachment to Escherichia coli WP2 similar to those of the wild type. One mutant, 109D153, exhibited depressed attachment at the restrictive temperature even though the Bdellovibrio cells were motile. The extent of 38.5 C attachment of 109D153 to E. coli is at the same level as that of wild-type 109D to Bacillus subtilis, a gram-positive, non-host organism. Subsequent detachments were revealed in the wild-type 109D-B. subtilis or mutant 109D153-Escherichia coli (38.5 C) cultures. These studies reveal a biphasic attachment phenomenon in the early interaction of Bdellovibrio with its host. It appears that, at the restrictive temperature, 109D153 is capable only of the initial, nonspecific type of attachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360541"}
{"pmid": "4360542", "title": "Isolation of a regulatory mutant of fructose-1,6-diphosphatase in Saccharomyces carlsbergensis.", "content": "Isolation of a regulatory mutant of fructose-1,6-diphosphatase in Saccharomyces carlsbergensis. By selecting for growth on glycerol, but absence of growth on glucose, a mutant of Saccharomyces carlsbergensis was isolated which does not grow on glucose, fructose, mannose, or sucrose, which shows long-term adaptation to maltose, but which can grow normally on galactose, ethanol, or glycerol. In the mutant, fructose diphosphatase is not inactivated after the addition of glucose, fructose or mannose to the medium, resulting in the simultaneous presence of fructose diphosphatase and phosphofructokinase activity. Under these conditions, a cycle is probably catalyzed between fructose-6-phosphate and fructose-1,6-diphosphate, resulting in the net consumption of adenosine triphosphate and an immediate stop of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360542"}
{"pmid": "4360544", "title": "Antisera to human cytomegaloviruses prepared in the guinea pig: specific immunofluorescence and complement fixation tests.", "content": "Antisera to human cytomegaloviruses prepared in the guinea pig: specific immunofluorescence and complement fixation tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360544"}
{"pmid": "4360543", "title": "Reversion of frameshift mutations by mutator genes in Escherichia coli.", "content": "Reversion of frameshift mutations by mutator genes in Escherichia coli. The Escherichia coli mutator genes mutU4, mutS3, and mut-25 (a possible allele of mutL), previously known to induce transitional base changes, increased significantly the frequencies of reversion of lacZ frameshift mutations. mutT1, previously shown to induce only the transversion of adenine-thymine to cytosine-guanine, had no effect on the reversion of lacZ frameshift mutations. With mutator genes other than mutT1, small increases were found in the frequencies of reversion of trpA frameshift mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360543"}
{"pmid": "4360545", "title": "Evidence for in vivo protection against murine-sarcoma virus-induced tumors by T lymphocytes from immune animals.", "content": "Evidence for in vivo protection against murine-sarcoma virus-induced tumors by T lymphocytes from immune animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360545"}
{"pmid": "4360539", "title": "Regulation of tryptophan biosynthesis in Saccharomyces cerevisiae: mode of action of 5-methyl-tryptophan and 5-methyl-tryptophan-sensitive mutants.", "content": "Regulation of tryptophan biosynthesis in Saccharomyces cerevisiae: mode of action of 5-methyl-tryptophan and 5-methyl-tryptophan-sensitive mutants. In a wild-type strain of Saccharomyces cerevisiae the tryptophan analogue dl-5-methyl-tryptophan (5MT) causes only a slight reduction of the growth rate. Uptake experiments indicate that the limited inhibition is partly due to low levels of 5MT inside the cell. On the other hand, this low concentration of 5MT leads to an increase in the activity of the tryptophan-biosynthetic enzymes. Evidence is presented that suggests that 5MT acts primarily through feedback inhibition of anthranilate synthase, the first enzyme of the pathway. A number of 5MT-sensitive mutants have been isolated, characterized, and assigned to one of the following three classes: class I, strains with altered activity and/or feedback sensitivity of anthranilate synthase; class II, strains with elevated uptake of 5MT; class III, mutants with altered regulation of the tryptophan-biosynthetic enzymes, which do not exhibit increases in activity in the presence of 5MT. This failure to exhibit increased enzyme activities in mutants of class III can also be observed after tryptophan starvation. Two mutants of class III show high sensitivity towards 3-amino-1,2,4-triazole. They can not exhibit derepression of some histidine- and arginine-biosynthetic enzymes under conditions that lead to an increase in these same enzymes in the wild-type strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360539"}
{"pmid": "4360548", "title": "Ruptured abdominal aortic aneurysm presenting with peripheral neuropathy.", "content": "Ruptured abdominal aortic aneurysm presenting with peripheral neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360548"}
{"pmid": "4360546", "title": "In vitro detection of immune responses to MTV-induced mammary tumors: activity of spleen cell preparations from both MTV-free and MTV-infected mice.", "content": "In vitro detection of immune responses to MTV-induced mammary tumors: activity of spleen cell preparations from both MTV-free and MTV-infected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360546"}
{"pmid": "4360547", "title": "Lymphocyte interferon production and transformation after Herpes simplex infections in humans.", "content": "Lymphocyte interferon production and transformation after Herpes simplex infections in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360547"}
{"pmid": "4360551", "title": "Comparison of insulin and proinsulin storage in an islet adenoma and adjacent pancreas.", "content": "Comparison of insulin and proinsulin storage in an islet adenoma and adjacent pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360551"}
{"pmid": "4360552", "title": "Perspectives on the renin-angiotensin-aldosterone system in hypertension.", "content": "Perspectives on the renin-angiotensin-aldosterone system in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360552"}
{"pmid": "4360549", "title": "Adrenocortical structure and function in rats bearing an adrenocorticotrophic hormone, growth hormone, and prolactin-secreting tumor.", "content": "Adrenocortical structure and function in rats bearing an adrenocorticotrophic hormone, growth hormone, and prolactin-secreting tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360549"}
{"pmid": "4360553", "title": "Alcohol and cancer.", "content": "Alcohol and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360553"}
{"pmid": "4360557", "title": "Hypothalamic inputs: methods, and five examples.", "content": "Hypothalamic inputs: methods, and five examples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360557"}
{"pmid": "4360558", "title": "Basic electrophysical mechanisms in neuroendocrinology.", "content": "Basic electrophysical mechanisms in neuroendocrinology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360558"}
{"pmid": "4360559", "title": "Hypothalamic mechanisms controlling pituitary function.", "content": "Hypothalamic mechanisms controlling pituitary function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360559"}
{"pmid": "4360562", "title": "Activation of lymphoid leucosis in chicks by irradiation.", "content": "Activation of lymphoid leucosis in chicks by irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360562"}
{"pmid": "4360578", "title": "Home care program cuts dollars and days.", "content": "Home care program cuts dollars and days.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360578"}
{"pmid": "4360579", "title": "The Baycrest experience: make your beds go further.", "content": "The Baycrest experience: make your beds go further.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360579"}
{"pmid": "4360583", "title": "Modes of Epstein-Barr virus infection in human floating cell lines.", "content": "Modes of Epstein-Barr virus infection in human floating cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360583"}
{"pmid": "4360581", "title": "Further studies on antibodies to early antigens induced by Epstein-Barr virus in nasopharyngeal carcinoma patients.", "content": "Further studies on antibodies to early antigens induced by Epstein-Barr virus in nasopharyngeal carcinoma patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360581"}
{"pmid": "4360582", "title": "Differential inhibition of histoformative aggregation of rat hepatoma cells in culture by concanavalin-A.", "content": "Differential inhibition of histoformative aggregation of rat hepatoma cells in culture by concanavalin-A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360582"}
{"pmid": "4360584", "title": "Tumor inhibitory effect of a new series of methanesulfonate of aminoglycols.", "content": "Tumor inhibitory effect of a new series of methanesulfonate of aminoglycols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360584"}
{"pmid": "4360586", "title": "Assay of Epstein-Barr virus by immunofluorescence.", "content": "Assay of Epstein-Barr virus by immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360586"}
{"pmid": "4360585", "title": "Heterogeneity of catalase in Morris hepatomas as revealed by isoelectric focusing and deae-cellulose column chromatography.", "content": "Heterogeneity of catalase in Morris hepatomas as revealed by isoelectric focusing and deae-cellulose column chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360585"}
{"pmid": "4360587", "title": "Brain tumors induced in adult monkeys by Schmidt-Ruppin strain of Rous sarcoma virus.", "content": "Brain tumors induced in adult monkeys by Schmidt-Ruppin strain of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360587"}
{"pmid": "4360589", "title": "Separation of dl-2-(3-phenoxyphenyl)propionic acid (fenoprofen) from its intermediates by thin layer chromatography.", "content": "Separation of dl-2-(3-phenoxyphenyl)propionic acid (fenoprofen) from its intermediates by thin layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360589"}
{"pmid": "4360590", "title": "An isolation and cleanup procedure for low levels of organochlorine pesticide residues in fats and oils.", "content": "An isolation and cleanup procedure for low levels of organochlorine pesticide residues in fats and oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360590"}
{"pmid": "4360591", "title": "Bluetongue virus transmission with Culicoides variipennis via embryonating chicken eggs.", "content": "Bluetongue virus transmission with Culicoides variipennis via embryonating chicken eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360591"}
{"pmid": "4360596", "title": "Physiology of neuromuscular transmission.", "content": "Physiology of neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360596"}
{"pmid": "4360599", "title": "Hepatic scintoscans.", "content": "Hepatic scintoscans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360599"}
{"pmid": "4360598", "title": "The work of the primary liver cancer research project: the value of liver function tests in the diagnosis of primary cancer of the liver in the Bantu.", "content": "The work of the primary liver cancer research project: the value of liver function tests in the diagnosis of primary cancer of the liver in the Bantu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360598"}
{"pmid": "4360615", "title": "The modern face of rheumatic fever.", "content": "The modern face of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360615"}
{"pmid": "4360621", "title": "Fibrinous pseudo-intimas within impermeable silastic-nylon velour. II. Development of \"neointima\".", "content": "Fibrinous pseudo-intimas within impermeable silastic-nylon velour. II. Development of \"neointima\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360621"}
{"pmid": "4360622", "title": "Hemolytic activity of mica dust and its relation to polyvinylpyridine N-oxide.", "content": "Hemolytic activity of mica dust and its relation to polyvinylpyridine N-oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360622"}
{"pmid": "4360623", "title": "Frey's syndrome: diagnosis and treatment.", "content": "Frey's syndrome: diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360623"}
{"pmid": "4360626", "title": "Replication of the resident non-defective SV40 in transformed human cells superinfected with DNA from a temperature-sensitive SV40 mutant.", "content": "Replication of the resident non-defective SV40 in transformed human cells superinfected with DNA from a temperature-sensitive SV40 mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360626"}
{"pmid": "4360627", "title": "Relationship between cell-interaction and antiviral activity of polyriboinosinic acid-polyribocytidylic acid in different cell cultures.", "content": "Relationship between cell-interaction and antiviral activity of polyriboinosinic acid-polyribocytidylic acid in different cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360627"}
{"pmid": "4360628", "title": "Electron microscopic observations on the mechanisms of entry of simian foamy virus in HEp-2 cells.", "content": "Electron microscopic observations on the mechanisms of entry of simian foamy virus in HEp-2 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360628"}
{"pmid": "4360629", "title": "Characterization of Herpes simplex virus types 1 and 2 adapted to growth at 25 degrees C.", "content": "Characterization of Herpes simplex virus types 1 and 2 adapted to growth at 25 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360629"}
{"pmid": "4360630", "title": "Mass production of human interferon in diploid cells stimulated by poly-I:C.", "content": "Mass production of human interferon in diploid cells stimulated by poly-I:C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360630"}
{"pmid": "4360632", "title": "A comparative study of Tanapox and Yaba viruses.", "content": "A comparative study of Tanapox and Yaba viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360632"}
{"pmid": "4360633", "title": "Interferon assay based on the inhibition of double-stranded reovirus RNA accumulation in mouse L cells.", "content": "Interferon assay based on the inhibition of double-stranded reovirus RNA accumulation in mouse L cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360633"}
{"pmid": "4360631", "title": "Haemolysis by Sendai virus: involvement of a virus protein component.", "content": "Haemolysis by Sendai virus: involvement of a virus protein component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360631"}
{"pmid": "4360634", "title": "Virocidal cleavage of disulphide bonds within structural proteins of Sendai virus.", "content": "Virocidal cleavage of disulphide bonds within structural proteins of Sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360634"}
{"pmid": "4360635", "title": "Blocking of the virus-enhancing activity of 5-methyl-2-D-ribobenzimidazole (MRB).", "content": "Blocking of the virus-enhancing activity of 5-methyl-2-D-ribobenzimidazole (MRB).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360635"}
{"pmid": "4360636", "title": "Behavior of human cytomegaloviruses in cell cultures of bovine and simian origin.", "content": "Behavior of human cytomegaloviruses in cell cultures of bovine and simian origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360636"}
{"pmid": "4360637", "title": "Spontaneous disappearance of tumorigenicity in a polyoma virus-induced neoplasm carried in vitro.", "content": "Spontaneous disappearance of tumorigenicity in a polyoma virus-induced neoplasm carried in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360637"}
{"pmid": "4360638", "title": "Regional cyclic nucleotide phosphodiesterase activity in cat central nervous system: effects of benzodiazepines.", "content": "Regional cyclic nucleotide phosphodiesterase activity in cat central nervous system: effects of benzodiazepines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360638"}
{"pmid": "4360639", "title": "Neurogenic hypercholesterolemia: influence upon lipoproteins.", "content": "Neurogenic hypercholesterolemia: influence upon lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360639"}
{"pmid": "4360641", "title": "Reversible inhibition by hyaluronidase of the insulinotropic action of tolbutamide in isolated hamster pancreatic islets.", "content": "Reversible inhibition by hyaluronidase of the insulinotropic action of tolbutamide in isolated hamster pancreatic islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360641"}
{"pmid": "4360640", "title": "The binding of 131-I-HCG to mature follicles isolated from the rabbit ovary.", "content": "The binding of 131-I-HCG to mature follicles isolated from the rabbit ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360640"}
{"pmid": "4360642", "title": "Tilorone: its selective effects on humoral and cell-mediated immunity.", "content": "Tilorone: its selective effects on humoral and cell-mediated immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360642"}
{"pmid": "4360643", "title": "Ontogenesis of circadian pituitary-adrenal periodicity in rats affected by neonatal treatment with ACTH.", "content": "Ontogenesis of circadian pituitary-adrenal periodicity in rats affected by neonatal treatment with ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360643"}
{"pmid": "4360645", "title": "A survey of cats and humans for prevalence of feline leukemia-sarcoma virus neutralizing serum antibodies.", "content": "A survey of cats and humans for prevalence of feline leukemia-sarcoma virus neutralizing serum antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360645"}
{"pmid": "4360644", "title": "Lack of correlation between initial vascular resistance and responses to vasoconstrictor stimuli in the perfused canine hindpaw.", "content": "Lack of correlation between initial vascular resistance and responses to vasoconstrictor stimuli in the perfused canine hindpaw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360644"}
{"pmid": "4360646", "title": "Effect of heparin on the kinetics of guinea pig and human postheparin lipase activity.", "content": "Effect of heparin on the kinetics of guinea pig and human postheparin lipase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360646"}
{"pmid": "4360647", "title": "Complement-fixing antibodies reactive with Epstein-Barr virus in sera of marmosets and prosimians.", "content": "Complement-fixing antibodies reactive with Epstein-Barr virus in sera of marmosets and prosimians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360647"}
{"pmid": "4360649", "title": "Microneutralization test for detection of rhinovirus antibodies.", "content": "Microneutralization test for detection of rhinovirus antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360649"}
{"pmid": "4360648", "title": "Lack of interaction between glucocorticoids and the kallikrein-kinin system.", "content": "Lack of interaction between glucocorticoids and the kallikrein-kinin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360648"}
{"pmid": "4360650", "title": "Studies of cyclic AMP effect on release of unsaturated vitamin B 12 binding capacity from human blood cells.", "content": "Studies of cyclic AMP effect on release of unsaturated vitamin B 12 binding capacity from human blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360650"}
{"pmid": "4360655", "title": "Ocular illness in association with adenovirus type 3 infection. An epidemic of conjunctivitis and keratoconjunctivitis in Stockholm 1969.", "content": "Ocular illness in association with adenovirus type 3 infection. An epidemic of conjunctivitis and keratoconjunctivitis in Stockholm 1969.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360655"}
{"pmid": "4360656", "title": "Osteoblastic multiple myeloma.", "content": "Osteoblastic multiple myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360656"}
{"pmid": "4360661", "title": "Spironolactone inclusions in an aldosteronoma.", "content": "Spironolactone inclusions in an aldosteronoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360661"}
{"pmid": "4360662", "title": "Angiographic evaluation of primary malignant hepatocellular tumors in children.", "content": "Angiographic evaluation of primary malignant hepatocellular tumors in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360662"}
{"pmid": "4360660", "title": "Cold-reactive antibodies in a case of congenital cytomegalovirus infection.", "content": "Cold-reactive antibodies in a case of congenital cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360660"}
{"pmid": "4360663", "title": "Phlebo-arterio-urography in the assessment of abdominal masses in children.", "content": "Phlebo-arterio-urography in the assessment of abdominal masses in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360663"}
{"pmid": "4360664", "title": "B-scan diagnostic ultrasound in the pediatric patient.", "content": "B-scan diagnostic ultrasound in the pediatric patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360664"}
{"pmid": "4360667", "title": "Prognostic factors in carcinoma of the stomach.", "content": "Prognostic factors in carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360667"}
{"pmid": "4360669", "title": "The anti-anaphylactic actions of disodium cromoglycate, theophylline, isoprenaline and prostaglandins.", "content": "The anti-anaphylactic actions of disodium cromoglycate, theophylline, isoprenaline and prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360669"}
{"pmid": "4360668", "title": "Studies on the reduction of tetrazolium salts. I. The isolation and characterisation of a half-formazan intermediate produced during the reduction of neotetrazolium chloride.", "content": "Studies on the reduction of tetrazolium salts. I. The isolation and characterisation of a half-formazan intermediate produced during the reduction of neotetrazolium chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360668"}
{"pmid": "4360670", "title": "Thin layer chromatography and in situ fluorometry for the quantitative determination of dimethoate and malathion in lettuce.", "content": "Thin layer chromatography and in situ fluorometry for the quantitative determination of dimethoate and malathion in lettuce.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360670"}
{"pmid": "4360671", "title": "Microbiological methods. Collaborative study of the alpha-toxin method for estimating population levels of Clostridium perfringens in food.", "content": "Microbiological methods. Collaborative study of the alpha-toxin method for estimating population levels of Clostridium perfringens in food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360671"}
{"pmid": "4360672", "title": "Anaerobic synthesis of apocytochrome oxidase and assembly of the holoenzyme in yeast protoplasts.", "content": "Anaerobic synthesis of apocytochrome oxidase and assembly of the holoenzyme in yeast protoplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360672"}
{"pmid": "4360673", "title": "Coproporphyrin 3, inhibitor of the synthesis of cytochrome oxidase in anaerobic yeast protoplasts.", "content": "Coproporphyrin 3, inhibitor of the synthesis of cytochrome oxidase in anaerobic yeast protoplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360673"}
{"pmid": "4360674", "title": "Interaction of an active glycopeptide from chick skin collagen (alpha 1-CB5) with human platelets.", "content": "Interaction of an active glycopeptide from chick skin collagen (alpha 1-CB5) with human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360674"}
{"pmid": "4360677", "title": "Glucocorticoid receptors in rat thymocytes. Interactions with the antiglucocorticoid cortexolone and mechanism of its action.", "content": "Glucocorticoid receptors in rat thymocytes. Interactions with the antiglucocorticoid cortexolone and mechanism of its action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360677"}
{"pmid": "4360675", "title": "Spectroscopic studies on the conformation of cytochrome c and apocytochrome c.", "content": "Spectroscopic studies on the conformation of cytochrome c and apocytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360675"}
{"pmid": "4360676", "title": "Interaction of nucleotides with liver uridine diphosphate-glucose-4'-epimerase.", "content": "Interaction of nucleotides with liver uridine diphosphate-glucose-4'-epimerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360676"}
{"pmid": "4360678", "title": "Effects of 25-hydroxyvitamin D3 on rat duodenum, jejunum, and ileum. Correlation of calcium active transport with tissue levels of vitamin D3 metabolites.", "content": "Effects of 25-hydroxyvitamin D3 on rat duodenum, jejunum, and ileum. Correlation of calcium active transport with tissue levels of vitamin D3 metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360678"}
{"pmid": "4360679", "title": "Studies on the regulation of gluconeogenesis in isolated rat liver cells by epinephrine and glucagon.", "content": "Studies on the regulation of gluconeogenesis in isolated rat liver cells by epinephrine and glucagon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360679"}
{"pmid": "4360680", "title": "Protein and glycoprotein subunit composition of plasma membrane from chick embryo fibroblasts.", "content": "Protein and glycoprotein subunit composition of plasma membrane from chick embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360680"}
{"pmid": "4360681", "title": "Characterization of protein kinases from rabbit reticulocytes.", "content": "Characterization of protein kinases from rabbit reticulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360681"}
{"pmid": "4360682", "title": "The role of ribosomal proteins L7 and L-12 in polypeptide chain initiation in Escherichia coli.", "content": "The role of ribosomal proteins L7 and L-12 in polypeptide chain initiation in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360682"}
{"pmid": "4360683", "title": "Structural study of the blood group A active glycolipids of hog gastric mucosa.", "content": "Structural study of the blood group A active glycolipids of hog gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360683"}
{"pmid": "4360684", "title": "Testicular adenosine 3':5'-monophosphate-dependent protein kinase. Regulation by follicle-stimulating hormone.", "content": "Testicular adenosine 3':5'-monophosphate-dependent protein kinase. Regulation by follicle-stimulating hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360684"}
{"pmid": "4360685", "title": "1 Alpha,25-dihydroxycholecalciferol receptors in intestine. I. Association of 1 alpha,25-dihydroxycholecalciferol with intestinal mucosa chromatin.", "content": "1 Alpha,25-dihydroxycholecalciferol receptors in intestine. I. Association of 1 alpha,25-dihydroxycholecalciferol with intestinal mucosa chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360685"}
{"pmid": "4360686", "title": "1 Alpha,25-dihydroxycholecalciferol receptors in intestine. II. Temperature-dependent transfer of the hormone to chromatin via a specific cytosol receptor.", "content": "1 Alpha,25-dihydroxycholecalciferol receptors in intestine. II. Temperature-dependent transfer of the hormone to chromatin via a specific cytosol receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360686"}
{"pmid": "4360687", "title": "Rabbit muscle phosphofructokinase. II. Product and dead end inhibition.", "content": "Rabbit muscle phosphofructokinase. II. Product and dead end inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360687"}
{"pmid": "4360688", "title": "The regulation of lipogenesis by cyclic nucleotides in intact hepatocytes prepared by a simplified technique.", "content": "The regulation of lipogenesis by cyclic nucleotides in intact hepatocytes prepared by a simplified technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360688"}
{"pmid": "4360690", "title": "Thin-layer chromatography of various analgesics, antipyretics and anti-inflammatory agents.", "content": "Thin-layer chromatography of various analgesics, antipyretics and anti-inflammatory agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360690"}
{"pmid": "4360689", "title": "Enzyme-catalyzed free radical reactions with nicotinamide adenine nucleotides. II. Lactate dehydrogenase-catalyzed oxidation of reduced nicotinamide adenine dinucleotide by superoxide radicals generated by xanthine oxidase.", "content": "Enzyme-catalyzed free radical reactions with nicotinamide adenine nucleotides. II. Lactate dehydrogenase-catalyzed oxidation of reduced nicotinamide adenine dinucleotide by superoxide radicals generated by xanthine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360689"}
{"pmid": "4360691", "title": "Cerebral arterial spasm. 1. In vitro contractile activity of vasoactive agents on canine basilar and middle cerebral arteries.", "content": "Cerebral arterial spasm. 1. In vitro contractile activity of vasoactive agents on canine basilar and middle cerebral arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360691"}
{"pmid": "4360694", "title": "Cellular action of antidiuretic hormone in nephrogenic diabetes insipidus.", "content": "Cellular action of antidiuretic hormone in nephrogenic diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360694"}
{"pmid": "4360697", "title": "Detection of Australia antigen (HBAg) in blood donors and hepatoma patients in Mozambique.", "content": "Detection of Australia antigen (HBAg) in blood donors and hepatoma patients in Mozambique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360697"}
{"pmid": "4360695", "title": "Effect of heterologous transplantation of H4-II-E rat hepatoma cells into the cheek pouch of hydrocortisone treated hamsters.", "content": "Effect of heterologous transplantation of H4-II-E rat hepatoma cells into the cheek pouch of hydrocortisone treated hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360695"}
{"pmid": "4360700", "title": "Group I inhibition in Ib excited ventral spinocerebellar tract neurones.", "content": "Group I inhibition in Ib excited ventral spinocerebellar tract neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360700"}
{"pmid": "4360699", "title": "Effects of 6-OH-dopamine on the autonomic nerves of the rabbit myometrium.", "content": "Effects of 6-OH-dopamine on the autonomic nerves of the rabbit myometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360699"}
{"pmid": "4360701", "title": "Vascular and metabolic effects of theophylline, dibuturyl cyclic AMP and dibuturyl cyclic GMP in canine subcutaneous adipose tissue in situ.", "content": "Vascular and metabolic effects of theophylline, dibuturyl cyclic AMP and dibuturyl cyclic GMP in canine subcutaneous adipose tissue in situ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360701"}
{"pmid": "4360702", "title": "Observations on closed tissue cultures of sympathetic ganglia of chick embryos in media buffered with N-tris-(hydroxymethyl) methyl-glycine or N-2-hydroxy-ethylpiperazine-N-2-ethanesulfonic acid.", "content": "Observations on closed tissue cultures of sympathetic ganglia of chick embryos in media buffered with N-tris-(hydroxymethyl) methyl-glycine or N-2-hydroxy-ethylpiperazine-N-2-ethanesulfonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360702"}
{"pmid": "4360703", "title": "A long term study on the ocular lesions in streptozotocin diabetic rats.", "content": "A long term study on the ocular lesions in streptozotocin diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360703"}
{"pmid": "4360705", "title": "Stimulation of dendritogenesis in human melanocytes by dibutyryl adenosine 3', 5'-cyclic monophosphate in vitro.", "content": "Stimulation of dendritogenesis in human melanocytes by dibutyryl adenosine 3', 5'-cyclic monophosphate in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360705"}
{"pmid": "4360704", "title": "Langerhans cells in cell culture. Survival and identification.", "content": "Langerhans cells in cell culture. Survival and identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360704"}
{"pmid": "4360711", "title": "Influence of mitochondria on phospholipid synthesis in preparations from rat liver.", "content": "Influence of mitochondria on phospholipid synthesis in preparations from rat liver. 1. The addition of mitochondria to an incubation system containing the soluble and microsomal fractions of rat liver enhances severalfold the incorporation of each of ethanolamine, phosphorylethanolamine and CDP-ethanolamine into phosphatidylethanolamine. 2. In the presence of microsomal, mitochondrial and soluble fractions, CDP-ethanolamine exhibits the greatest initial rate of incorporation (approx. 6nmol/h per mg of protein), being slightly faster than that of phosphorylethanolamine (approx. 5nmol/h per mg of protein). Incorporation of ethanolamine proceeds very slowly for the first 20min and only after 30min gives rates approaching those of the other two precursors. 3. By using a substrate ;dilution' technique it was shown that in the reconstituted system the affinity of each of the enzymes for their respective substrates is very high: 10mum for ethanolamine, 25mum for phosphorylethanolamine and 5mum for CDP-ethanolamine. 4. Isolation of the mitochondrial and microsomal fractions from the medium after incubation together with phosphorylethanolamine showed that about 70% of the total radioactivity was present in the microsomal fraction and about 30% in the mitochondria after only 20min. Similar experiments with ethanolamine as precursor revealed that after 20min only about 15% of the total radioactivity was present in the mitochondria but that after 40min about 30% was present in this fraction. 5. Heating and phospholipase treatment of mitochondria, but not freeze-thawing, eliminated the stimulatory effect of mitochondria on phospholipid synthesis. 6. The reconstituted system exhibits an absolute requirement for Mg(2+) (2mm gave maximal rates) and is inhibited by very low concentrations of Ca(2+) (100mum-Ca(2+) produced half-maximal inhibition with 3mm-Mg(2+)). Further addition of Mg(2+) overcame the Ca(2+) inhibition, suggesting that the inhibitory effect is readily reversible. 7. The concept that modification of the Mg(2+)/Ca(2+) ratio is a means of controlling the rate of cellular phospholipid synthesis is introduced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360711"}
{"pmid": "4360713", "title": "Phosphatidylinositol kinase. A component of the chromaffin-granule membrane.", "content": "Phosphatidylinositol kinase. A component of the chromaffin-granule membrane. Phosphorylation of bovine chromaffin granules by ATP leads to the formation of diphosphoinositide in the granule membrane. Both phosphatidylinositol kinase and its substrate are components of this membrane, and triphosphoinositide is not formed under the conditions of the assay. The reaction is Mg(2+)-dependent and is stimulated by Mn(2+) and F(-) ions. The initial reaction is rapid, with a broad pH profile and a ;transition' temperature for its activation energy at 27 degrees C. The apparent K(m) for ATP is 5mum. ATP, N-ethylmaleimide, Cu(2+) ions and NaIO(4) are inhibitory. The phospholipids of chromaffin-granule membranes have been analysed: 6.8% of the lipid P is found in phosphatidylinositol, and only 2-3% in phosphatidylserine. Comparison of the rate of phosphorylation of intact and lysed granules suggests that the sites for phosphorylation are on the outer (cytoplasmic) surface of the granules, and diphosphoinositide may therefore make an important contribution to the charge of the chromaffin granule in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360713"}
{"pmid": "4360712", "title": "Plasma lipoproteins and the synthesis and turnover of plasma triglyceride in normal and genetically obese mice.", "content": "Plasma lipoproteins and the synthesis and turnover of plasma triglyceride in normal and genetically obese mice. 1. Lipoproteins in the plasma of mice were characterized by agarose-gel chromatography and polyacrylamide-gel electrophoresis: genetically obese (ob/ob) mice exhibited hyperlipoproteinaemia (compared with lean mice), largely owing to an increase in the concentration of cholesterol in high-density lipoprotein. Plasma concentrations of triglyceride and phospholipid were not markedly increased in genetically obese mice. 2. The formation of glycerolipids in liver and plasma was investigated with (14)C-labelled precursors. The synthesis of hepatic triglyceride and phospholipid from glucose or palmitate was enhanced in ob/ob mice, compared with lean mice. The rate of entry of triglyceride into plasma, calculated from the time-course of incorporation of (14)C from [(14)C]palmitate into plasma triglyceride, was increased in ob/ob mice (0.5mumol of fatty acid/min, compared with 0.2 in lean mice). 3. The removal from plasma of murine lipoprotein triglyceride-[(14)C]fatty acid was increased in ob/ob mice (half-time 2.2min, compared with 7.2min in lean mice). Similar results were obtained with an injected lipid emulsion (Intralipid). 4. From these measurements, estimates of the rates of turnover of plasma triglyceride in mice (fed on a mixed diet, female, 3 months old) are about 1.0mumol of fatty acid/min in ob/ob mice, and 0.25 in lean mice. 5. The major precursor of hepatic and plasma triglyceride in lean and ob/ob mice was calculated to be plasma free fatty acid. 6. These results are discussed, in connexion with the role of the liver in triglyceride metabolism in mice, especially in relation to genetic obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360712"}
{"pmid": "4360714", "title": "Stimulation of ribonucleic acid polymerase activity in vitro by prostatic steroid-protein receptor complexes.", "content": "Stimulation of ribonucleic acid polymerase activity in vitro by prostatic steroid-protein receptor complexes. A system has been developed which allows the stimulation in vitro of prostatic RNA polymerase by prostatic 5alpha-dihydrotestosterone-protein receptor complexes prepared from the tissues of castrated rats. The reconstitution in vitro of such a system necessitates the purification of several subcellular components. Two 5alpha-dihydrotestosterone-receptor complexes are located in the prostatic soluble supernatant fraction, separable by selective ammonium sulphate fractionation, and one complex can be isolated from the nuclear fraction. In the presence of all these complexes, stimulation of RNA polymerase in intact nuclei and nucleoli was observed. The complexes also increased the activity of the enzyme solubilized from whole nuclei. Greater stimulation of this system was noted in the presence of prostatic chromatin as template, as compared with that observed with calf thymus DNA or liver chromatin as template. The effects of the complexes on subnuclear forms of RNA polymerase, of nucleolar and extranucleolar origin, are also described. RNA polymerase solubilized from nucleoli is more susceptible to stimulation by the 5alpha-dihydrotestosterone-receptor complexes than is the ;nucleoplasmic' enzyme. Stimulation occurs less readily in the presence of Mn(2+) and at high ionic strength than in the presence of Mg(2+) and at low ionic strength. Preliminary experiments show that prostatic nucleolar RNA polymerase transcribes prostatic chromatin poorly as compared with the nucleoplasmic enzyme. The observations reported indicate an involvement of non-histone proteins associated with DNA in the process by which stimulation of enzyme activity by the 5alpha-dihydrotestosterone-receptor complexes is achieved. The implications of these findings in the mechanism of steroid hormone action is considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360714"}
{"pmid": "4360715", "title": "Synthesis and degradation of mitochondrial components in hypertrophied rat heart.", "content": "Synthesis and degradation of mitochondrial components in hypertrophied rat heart. The accumulation of inner mitochondrial components of rat heart was studied 1 and 3 days after constriction of the ascending aorta of rats. By 1 day after aortic constriction, the activities of three mitochondrial respiratory enzymes/mg of cardiac homogenate protein were increased; after 3 days, specific activities had levelled off or decreased. Selective accumulation of inner mitochondrial membrane components 24h after aortic constriction was further indicated by increased left ventricular cytochrome c concentration (nmol/mg of protein). By 3 days after surgery, cytochrome c concentration was significantly diminished. Low-temperature spectroscopy of isolated mitochondria showed that the ratios of cytochromes c, b and a+a(3) remained unchanged after aortic constriction, suggesting that cytochrome c was a good indicator of the response of the other mitochondrial inner-membrane cytochromes as well. The effect of cardiac hypertrophy on the turnover of cytochrome c was also examined. Cytochrome c was labelled in its haem group with delta-amino[2,3-(3)H(2)]laevulinate 3 days before aortic constriction. By 1 day after surgery the total ventricular radioactivity in cytochrome c of aortic banded animals was significantly higher than in sham-operated controls, indicating a decreased degradation rate in the former during the first postoperative day. delta-Aminolaevulinate was shown to be a particularly suitable precursor for such turnover studies, since it results in rapid pulse-labelling of cytochrome c (peak activity in 90min), is rapidly removed from the precursor pool (t((1/2))=30min) and is not reutilized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360715"}
{"pmid": "4360716", "title": "The degradation of L-histidine in the rat. The formation of imidazolylpyruvate, imidazolyl-lactate and imidazolylpropionate.", "content": "The degradation of L-histidine in the rat. The formation of imidazolylpyruvate, imidazolyl-lactate and imidazolylpropionate. 1. Soluble and mitochondrial forms of histidine-pyruvate aminotransferase were separated from rat liver preparations by chromatography on DEAE-cellulose. 2. These enzymes were characterized with respect to substrate specificity, substrate affinity, pH optimum, stability and molecular weight by chromatography on Sephadex G-200. 3. Each enzyme has a relatively broad specificity showing significant activity towards l-phenylalanine and l-tyrosine and catalysing transamination with a number of monocarboxylic 2-oxo acids. 2-Oxoglutarate is not a substrate for either enzyme. 4. The molecular weights of the two enzymes, by chromatography on Sephadex G-200, are in the range 130000-150000. 5. The formation in vitro of imidazolyl-lactate from imidazolylpyruvate and NADH was demonstrated by using liver preparations. 6. From a study of imidazolyl-lactate-NAD(+) oxidoreductase activity after electrophoresis of liver preparations on polyacrylamide gel, and from an examination of the activity of l-lactate-NAD(+) oxidoreductase (EC 1.1.1.27) towards imidazolylpyruvate, it is concluded that this latter enzyme is responsible for the formation of imidazolyl-lactate in the liver. 7. Preparations of bacteria obtained from rat faeces form imidazolylpropionate from l-histidine and urocanate without further subculture. The amount of imidazolylpropionate formed is increased under anaerobic conditions and more so in an atmosphere of H(2). It is suggested that the gut flora of the rat contribute largely, if not exclusively, to the formation of imidazolylpropionate normally found in the urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360716"}
{"pmid": "4360717", "title": "Quantitative studies on ferredoxin in greening bean leaves.", "content": "Quantitative studies on ferredoxin in greening bean leaves. Two methods of measuring small amounts of the iron-sulphur protein ferredoxin are described. One involves measurements of the signal at g=1.96 produced by reduced ferredoxin in an e.p.r. (electron-paramagnetic-resonance) spectrometer; the other depends on the rate of ferredoxin-dependent electron transport in a chloroplast bioassay measured in an O(2) electrode. These methods of measurement were used to examine the development of ferredoxin during the greening of etiolated bean leaves. Ferredoxin is present in low concentrations in the leaves and cotyledons of 14-day-old etiolated beans (Phaseolus vulgaris L. var. Canadian Wonder), and develops in a linear manner with time when the leaves are illuminated. This synthesis appears to be independent of chlorophyll synthesis during the early stages of greening. However, the chlorophyll/ferredoxin ratio reaches a final value of approx. 360 irrespective of the light intensity, indicating the existence of a control mechanism operative in deciding the stoicheiometry of these components in the mature chloroplast. The ferredoxin synthesis appears to be light-dependent, and red light is the most effective in its promotion. The effect of red illumination is not reversed by far-red light, indicating the absence of a phytochrome control of ferredoxin synthesis. From experiments using specific inhibitors of chloroplast protein synthesis, it is concluded that ferredoxin is synthesized on cytoplasmic ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360717"}
{"pmid": "4360719", "title": "The ultrastructure of Geotrichum candidum hyphae.", "content": "The ultrastructure of Geotrichum candidum hyphae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360719"}
{"pmid": "4360718", "title": "Inhibition by ricin of protein synthesis in vitro: 60 S ribosomal subunit as the target of the toxin.", "content": "Inhibition by ricin of protein synthesis in vitro: 60 S ribosomal subunit as the target of the toxin. Poly(U)-directed polyphenylalanine synthesis by rat liver ribosomes is strongly inhibited by ricin. Experiments involving hybridization between subunits derived from normal and ricin-treated ribosomes demonstrate that the 60S subunit is the site of action of the toxin. The toxin inactivates the 60S subunit independently of the presence of the 40S subunit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360718"}
{"pmid": "4360720", "title": "Recent developments with the L5178Y TK heterozygote mutagen assay system.", "content": "Recent developments with the L5178Y TK heterozygote mutagen assay system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360720"}
{"pmid": "4360721", "title": "Use of the asparagine auxotroph of the L5178Y murine leukemia for the detection of chemical mutagens in vitro and in the host-mediated assay.", "content": "Use of the asparagine auxotroph of the L5178Y murine leukemia for the detection of chemical mutagens in vitro and in the host-mediated assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360721"}
{"pmid": "4360708", "title": "The immunodepressive effect of infectious bursal disease virus in chickens.", "content": "The immunodepressive effect of infectious bursal disease virus in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360708"}
{"pmid": "4360709", "title": "Investigation of an increase of solid tumors in chickens vaccinated against Marek's disease.", "content": "Investigation of an increase of solid tumors in chickens vaccinated against Marek's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360709"}
{"pmid": "4360723", "title": "Current status of the host-mediated L5178Y system for detecting chemical mutagens.", "content": "Current status of the host-mediated L5178Y system for detecting chemical mutagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360723"}
{"pmid": "4360722", "title": "Evaluation of chromosome aberration effects of chemicals on mouse germ cells.", "content": "Evaluation of chromosome aberration effects of chemicals on mouse germ cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360722"}
{"pmid": "4360725", "title": "Some primary considerations in the interpretation of the dominant-lethal assay.", "content": "Some primary considerations in the interpretation of the dominant-lethal assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360725"}
{"pmid": "4360724", "title": "Chromosome aberrations as a measure of mutagenesis: comparisons in vitro and in vivo and in somatic and germ cells.", "content": "Chromosome aberrations as a measure of mutagenesis: comparisons in vitro and in vivo and in somatic and germ cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360724"}
{"pmid": "4360710", "title": "Atypical fowlpox in a poultry farm in Illinois.", "content": "Atypical fowlpox in a poultry farm in Illinois.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360710"}
{"pmid": "4360726", "title": "New developments in mutagenicity screening techniques with yeast.", "content": "New developments in mutagenicity screening techniques with yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360726"}
{"pmid": "4360727", "title": "Estrogen target cells in the skin.", "content": "Estrogen target cells in the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360727"}
{"pmid": "4360730", "title": "Strategies for developing multisource funding for community mental health centers.", "content": "Strategies for developing multisource funding for community mental health centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360730"}
{"pmid": "4360729", "title": "Scanning electron microscopic study of normal and molar trophoblast.", "content": "Scanning electron microscopic study of normal and molar trophoblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360729"}
{"pmid": "4360728", "title": "Gynecologic aspects of breast disease.", "content": "Gynecologic aspects of breast disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360728"}
{"pmid": "4360731", "title": "A process to help community mental health boards plan programs and facilities.", "content": "A process to help community mental health boards plan programs and facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360731"}
{"pmid": "4360736", "title": "Myomycin, a new antibiotic.", "content": "Myomycin, a new antibiotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360736"}
{"pmid": "4360735", "title": "Surgical correction of islet cell adenocarcinoma in a dog.", "content": "Surgical correction of islet cell adenocarcinoma in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360735"}
{"pmid": "4360737", "title": "Ultrastructure of the crayfish kidney--coelomosac, labyrinth, nephridial canal.", "content": "Ultrastructure of the crayfish kidney--coelomosac, labyrinth, nephridial canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360737"}
{"pmid": "4360740", "title": "Virology and the nonhuman primate.", "content": "Virology and the nonhuman primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360740"}
{"pmid": "4360739", "title": "Editorial: The kidney and uric acid excretion in man.", "content": "Editorial: The kidney and uric acid excretion in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360739"}
{"pmid": "4360734", "title": "Cell culture techniques in the search for cancer viruses of man.", "content": "Cell culture techniques in the search for cancer viruses of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360734"}
{"pmid": "4360732", "title": "Cell transformation by viruses. I. Significance of virus-specific antigens induced by deoxyribonucleic acid-containing tumor viruses. II. Complementary ribonucleic acid in cells transformed by ribonucleic acid-containing tumor viruses.", "content": "Cell transformation by viruses. I. Significance of virus-specific antigens induced by deoxyribonucleic acid-containing tumor viruses. II. Complementary ribonucleic acid in cells transformed by ribonucleic acid-containing tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360732"}
{"pmid": "4360741", "title": "Use of nonhuman primates in virus research.", "content": "Use of nonhuman primates in virus research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360741"}
{"pmid": "4360742", "title": "Activities of the NIH-WHO regional reference center for simian viruses.", "content": "Activities of the NIH-WHO regional reference center for simian viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360742"}
{"pmid": "4360744", "title": "Natural and experimental infections of nonhuman primates with respiratory viruses.", "content": "Natural and experimental infections of nonhuman primates with respiratory viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360744"}
{"pmid": "4360743", "title": "Viral epizootics in captive nonhuman primates.", "content": "Viral epizootics in captive nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360743"}
{"pmid": "4360733", "title": "Biochemical aspects of viral transformation.", "content": "Biochemical aspects of viral transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360733"}
{"pmid": "4360746", "title": "Spontaneous lymphoma of the nonhuman primate.", "content": "Spontaneous lymphoma of the nonhuman primate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360746"}
{"pmid": "4360745", "title": "C-type oncogenic viruses of nonhuman primates.", "content": "C-type oncogenic viruses of nonhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360745"}
{"pmid": "4360747", "title": "Virus from stumptailed monkey (Macaca arctoides) kidney cultures.", "content": "Virus from stumptailed monkey (Macaca arctoides) kidney cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360747"}
{"pmid": "4360748", "title": "Pathology and clinical history of Delta herpesvirus infection in patas monkeys.", "content": "Pathology and clinical history of Delta herpesvirus infection in patas monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360748"}
{"pmid": "4360749", "title": "Recent studies on the isolation and characterization of Delta herpesvirus.", "content": "Recent studies on the isolation and characterization of Delta herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360749"}
{"pmid": "4360750", "title": "Ascorbic acid (vitamin C) and its effects on parainfluenza type 3 virus infection in cotton-topped marmosets.", "content": "Ascorbic acid (vitamin C) and its effects on parainfluenza type 3 virus infection in cotton-topped marmosets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360750"}
{"pmid": "4360751", "title": "Spontaneous neoplasms of nonhuman primates. Attempted transmission to immunosuppressed hosts and in vitro characterization.", "content": "Spontaneous neoplasms of nonhuman primates. Attempted transmission to immunosuppressed hosts and in vitro characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360751"}
{"pmid": "4360752", "title": "Comparative protection by polyoma virus and xenogenic polyoma-induced tumour cells against tumour allograft.", "content": "Comparative protection by polyoma virus and xenogenic polyoma-induced tumour cells against tumour allograft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360752"}
{"pmid": "4360753", "title": "Use of oral antibiotics in protected units environment: clinical effectiveness and role in the emergence of antibiotic-resistant strains.", "content": "Use of oral antibiotics in protected units environment: clinical effectiveness and role in the emergence of antibiotic-resistant strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360753"}
{"pmid": "4360757", "title": "Clinicopathology of equine rhinopneumonitis abortion in central Iowa.", "content": "Clinicopathology of equine rhinopneumonitis abortion in central Iowa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360757"}
{"pmid": "4360754", "title": "The effects of circumcision on sleep-wake states in human neonates.", "content": "The effects of circumcision on sleep-wake states in human neonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360754"}
{"pmid": "4360760", "title": "Studies on nucleic acids in RSV-induced mouse ascites sarcoma cells. Base compositions and chromatographic behaviors.", "content": "Studies on nucleic acids in RSV-induced mouse ascites sarcoma cells. Base compositions and chromatographic behaviors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360760"}
{"pmid": "4360761", "title": "Adenosine 3', 5'-monophosphate-dependent protein kinase from SV 40-induced hamster tumor.", "content": "Adenosine 3', 5'-monophosphate-dependent protein kinase from SV 40-induced hamster tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360761"}
{"pmid": "4360762", "title": "Immunofluorescent and electron microscopic studies of cultured human cells successively transformed by Rous sarcoma virus and simian virus 40.", "content": "Immunofluorescent and electron microscopic studies of cultured human cells successively transformed by Rous sarcoma virus and simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360762"}
{"pmid": "4360763", "title": "Molecular forms and activities of glucose 6-phosphate dehydrogenase in cultured human cells.", "content": "Molecular forms and activities of glucose 6-phosphate dehydrogenase in cultured human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360763"}
{"pmid": "4360756", "title": "Immunologic deficiency in Hodgkin's disease.", "content": "Immunologic deficiency in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360756"}
{"pmid": "4360765", "title": "Human immunoglobulin M antibody in the sero-diagnosis of Japanese encephalitis virus infections.", "content": "Human immunoglobulin M antibody in the sero-diagnosis of Japanese encephalitis virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360765"}
{"pmid": "4360766", "title": "Family-based epidemiologic studies. The second Wade Hampton Frost Lecture.", "content": "Family-based epidemiologic studies. The second Wade Hampton Frost Lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360766"}
{"pmid": "4360767", "title": "Evolutionary aspects of interactions between human host and virus populations.", "content": "Evolutionary aspects of interactions between human host and virus populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360767"}
{"pmid": "4360768", "title": "Epidemic of adenovirus type 7 acute conjunctivitis in swimmers.", "content": "Epidemic of adenovirus type 7 acute conjunctivitis in swimmers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360768"}
{"pmid": "4360769", "title": "Enzymatic production of experimental emphysema in the dog. Route of exposure.", "content": "Enzymatic production of experimental emphysema in the dog. Route of exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360769"}
{"pmid": "4360770", "title": "Electron microscopic studies on the parafollicular cells and parafollicular cell complexes in the dog.", "content": "Electron microscopic studies on the parafollicular cells and parafollicular cell complexes in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360770"}
{"pmid": "4360771", "title": "The central nervous system, liver, and spleen of FM mice. Ultrastructural, histochemical, and biochemical studies.", "content": "The central nervous system, liver, and spleen of FM mice. Ultrastructural, histochemical, and biochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360771"}
{"pmid": "4360774", "title": "Action of micrococcal nuclease on chemically modified deoxyribonucleic acid.", "content": "Action of micrococcal nuclease on chemically modified deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360774"}
{"pmid": "4360775", "title": "Studies on the relationship between deoxyribonucleic acid polymerase activity and intracisternal A-type particles in mouse myeloma.", "content": "Studies on the relationship between deoxyribonucleic acid polymerase activity and intracisternal A-type particles in mouse myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360775"}
{"pmid": "4360776", "title": "Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.", "content": "Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360776"}
{"pmid": "4360777", "title": "Isolation and partial characterization of chimpanzee plasma high density lipoproteins and their apolipoproteins.", "content": "Isolation and partial characterization of chimpanzee plasma high density lipoproteins and their apolipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360777"}
{"pmid": "4360778", "title": "Chemical structure of a novel glycolipid from an extreme thermophile, Flavobacterium thermophilum.", "content": "Chemical structure of a novel glycolipid from an extreme thermophile, Flavobacterium thermophilum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360778"}
{"pmid": "4360780", "title": "Frequency and temperature dependence of the proton relaxation rates of solvent and substrate interaction with isocitrate dehydrogenase bound Mn(II).", "content": "Frequency and temperature dependence of the proton relaxation rates of solvent and substrate interaction with isocitrate dehydrogenase bound Mn(II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360780"}
{"pmid": "4360779", "title": "A comparison of the kinetics and stoichiometry of proton uptake with aldehyde reduction for liver alcohol dehydrogenase under single turnover conditions.", "content": "A comparison of the kinetics and stoichiometry of proton uptake with aldehyde reduction for liver alcohol dehydrogenase under single turnover conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360779"}
{"pmid": "4360782", "title": "Biosynthesis of viomycin. I. Origin of alpha, beta-diaminopropionic acid and serine.", "content": "Biosynthesis of viomycin. I. Origin of alpha, beta-diaminopropionic acid and serine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360782"}
{"pmid": "4360781", "title": "Electron and nuclear magnetic resonance studies of the interaction of pyruvate with transcarboxylase.", "content": "Electron and nuclear magnetic resonance studies of the interaction of pyruvate with transcarboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360781"}
{"pmid": "4360784", "title": "Circular dichroism spectra of the copper enzyme, galactose oxidase, in the presence of its substrates and products.", "content": "Circular dichroism spectra of the copper enzyme, galactose oxidase, in the presence of its substrates and products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360784"}
{"pmid": "4360785", "title": "Guanidine hydrochloride and acid denaturation of horse, cow, and Candida krusei cytochromes c.", "content": "Guanidine hydrochloride and acid denaturation of horse, cow, and Candida krusei cytochromes c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360785"}
{"pmid": "4360783", "title": "Biosynthesis of viomycin. II. Origin of beta-lysine and viomycidine.", "content": "Biosynthesis of viomycin. II. Origin of beta-lysine and viomycidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360783"}
{"pmid": "4360794", "title": "Duck hepatitis virus interactions with DDT and dieldrin in adult mallards.", "content": "Duck hepatitis virus interactions with DDT and dieldrin in adult mallards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360794"}
{"pmid": "4360795", "title": "PPD-stimulated interferon: in vitro macrophage-lymphocyte interaction in the production of a mediator of cellular immunity.", "content": "PPD-stimulated interferon: in vitro macrophage-lymphocyte interaction in the production of a mediator of cellular immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360795"}
{"pmid": "4360797", "title": "Derivative polarography of normal and cancerous tissue extracts and urines.", "content": "Derivative polarography of normal and cancerous tissue extracts and urines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360797"}
{"pmid": "4360796", "title": "Hormonal regulation of the immune response. II. Influence of pituitary and adrenal activity on immune responsiveness in vitro.", "content": "Hormonal regulation of the immune response. II. Influence of pituitary and adrenal activity on immune responsiveness in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360796"}
{"pmid": "4360799", "title": "Investigations on the specificity of hormone receptors in planarians.", "content": "Investigations on the specificity of hormone receptors in planarians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360799"}
{"pmid": "4360800", "title": "Structure and function of the transplanted pituitary in the seawater goby, Gillichthys mirabilis. I. The rostral pars distalis.", "content": "Structure and function of the transplanted pituitary in the seawater goby, Gillichthys mirabilis. I. The rostral pars distalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360800"}
{"pmid": "4360798", "title": "Enzymatic ADP-ribosylation of proteins and regulation of cellular activity.", "content": "Enzymatic ADP-ribosylation of proteins and regulation of cellular activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360798"}
{"pmid": "4360803", "title": "Relationship of craniofacial changes and skeletal age increments in females.", "content": "Relationship of craniofacial changes and skeletal age increments in females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360803"}
{"pmid": "4360804", "title": "A longitudinal examination of speed of reaction and speed of movement in young boys 7 to 13 years.", "content": "A longitudinal examination of speed of reaction and speed of movement in young boys 7 to 13 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360804"}
{"pmid": "4360805", "title": "Hepatoblastoma: pathological studies in a case.", "content": "Hepatoblastoma: pathological studies in a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360805"}
{"pmid": "4360801", "title": "Neural control of pituitary adrenal activity in Cyprinus carpio.", "content": "Neural control of pituitary adrenal activity in Cyprinus carpio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360801"}
{"pmid": "4360806", "title": "The phosphorescent state of indole. Observations using optically detected magnetic resonance.", "content": "The phosphorescent state of indole. Observations using optically detected magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360806"}
{"pmid": "4360807", "title": "Resolution of tryptophan phosphorescence from multiple sites in proteins using optical detection of magnetic resonance.", "content": "Resolution of tryptophan phosphorescence from multiple sites in proteins using optical detection of magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360807"}
{"pmid": "4360809", "title": "Collaborative study of an on-column periodate reaction method for the analysis of phenylpropanolamine hydrochloride in elixirs.", "content": "Collaborative study of an on-column periodate reaction method for the analysis of phenylpropanolamine hydrochloride in elixirs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360809"}
{"pmid": "4360808", "title": "Crystal structure of 1-(2-indol-3-ylethyl)-3-carbamidopyridinium chloride, an intramolecular model of the nicotinamide adenine dinucleotide--tryptophan charge-transfer complex.", "content": "Crystal structure of 1-(2-indol-3-ylethyl)-3-carbamidopyridinium chloride, an intramolecular model of the nicotinamide adenine dinucleotide--tryptophan charge-transfer complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360808"}
{"pmid": "4360810", "title": "Fructose-1, 6-bisphosphatase of an extreme thermophile.", "content": "Fructose-1, 6-bisphosphatase of an extreme thermophile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360810"}
{"pmid": "4360811", "title": "Electron and proton transport in Rhodospirillum rubrum chromatophores.", "content": "Electron and proton transport in Rhodospirillum rubrum chromatophores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360811"}
{"pmid": "4360813", "title": "Sparganum proliferum, a sparganum infected with a virus?", "content": "Sparganum proliferum, a sparganum infected with a virus?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360813"}
{"pmid": "4360812", "title": "Effect of lysolecithin and albumin on lecithin-cholesterol acyltransferase activity in human plasma.", "content": "Effect of lysolecithin and albumin on lecithin-cholesterol acyltransferase activity in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360812"}
{"pmid": "4360814", "title": "Isospora felis: development in cultured cells with some cytological observations.", "content": "Isospora felis: development in cultured cells with some cytological observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360814"}
{"pmid": "4360815", "title": "Hemoglobin absorption in the gut of a monogenetic Trematode, Dicilidophora merlangi.", "content": "Hemoglobin absorption in the gut of a monogenetic Trematode, Dicilidophora merlangi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360815"}
{"pmid": "4360816", "title": "Hyperlipidemia and coronary artery disease. Prinicples of diet and drug treatment.", "content": "Hyperlipidemia and coronary artery disease. Prinicples of diet and drug treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360816"}
{"pmid": "4360818", "title": "Anucleate mammalian cells: applications in cell biology and virology.", "content": "Anucleate mammalian cells: applications in cell biology and virology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360818"}
{"pmid": "4360817", "title": "HeLa cell plasma membranes.", "content": "HeLa cell plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360817"}
{"pmid": "4360819", "title": "Use and misuse of steroids.", "content": "Use and misuse of steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360819"}
{"pmid": "4360820", "title": "The role of macromolecules in neuronal function in Aplysia.", "content": "The role of macromolecules in neuronal function in Aplysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360820"}
{"pmid": "4360821", "title": "Reiter's disease: a review with special attention to cardiovascular and neurologic sequellae.", "content": "Reiter's disease: a review with special attention to cardiovascular and neurologic sequellae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360821"}
{"pmid": "4360823", "title": "Some aspects of the penicillin V-acylase produced by Rhodotorula glutinis var. glutinis.", "content": "Some aspects of the penicillin V-acylase produced by Rhodotorula glutinis var. glutinis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360823"}
{"pmid": "4360824", "title": "Preparation and evaluation of ACTH antibodies.", "content": "Preparation and evaluation of ACTH antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360824"}
{"pmid": "4360825", "title": "Arterial hypertension induced by 9 alpha-fluorocortisol in rats.", "content": "Arterial hypertension induced by 9 alpha-fluorocortisol in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360825"}
{"pmid": "4360826", "title": "Sex dimorphism in the adrenal of hamsters.", "content": "Sex dimorphism in the adrenal of hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360826"}
{"pmid": "4360827", "title": "Ultrastructural pathology of murine cytomegalovirus infection in cultured mouse nervous system tissue.", "content": "Ultrastructural pathology of murine cytomegalovirus infection in cultured mouse nervous system tissue. Mouse spinal cord-ganglia cultures were innoculated with murine cytomegalo-virus 14 days after explantation. Intranuclear virus was first observed 4 days after infection. The viruses, which occurred in four forms, were observed in increasing numbers during the ensuing 4 days. Differences were noted in the relative prevalence of certain of these forms in older as compared to younger cultures. This suggests that variations in virus form are related to virus maturation. Cytoplasmic viruses were occasionally observed, but their site of origin is not certain. A variety of cytoplasmic inclusions were seen, particularly in the older cultures. It seems likely that they represent specific cell responses to the presence of the virus. They were not observed in the control cultures, even though some of the latter did show severe degenerative changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360827"}
{"pmid": "4360831", "title": "Ultraviolet light and cytoplasmic tubules in lupus erythematosus.", "content": "Ultraviolet light and cytoplasmic tubules in lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360831"}
{"pmid": "4360830", "title": "Chordoma-like subcutaneous nodules in an infant.", "content": "Chordoma-like subcutaneous nodules in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360830"}
{"pmid": "4360832", "title": "Proceedings: Cylindroma.", "content": "Proceedings: Cylindroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360832"}
{"pmid": "4360834", "title": "The genetics of herpesvirus.", "content": "The genetics of herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360834"}
{"pmid": "4360836", "title": "Light microscopic observations of transplantable mouse hepatomas.", "content": "Light microscopic observations of transplantable mouse hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360836"}
{"pmid": "4360837", "title": "A direct relationship between immune competence and the subcutaneous growth rate of a malignant murine lung tumor.", "content": "A direct relationship between immune competence and the subcutaneous growth rate of a malignant murine lung tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360837"}
{"pmid": "4360835", "title": "Nucleotide contents of ascites hepatoma cells and their changes induced by D-galactosamine.", "content": "Nucleotide contents of ascites hepatoma cells and their changes induced by D-galactosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360835"}
{"pmid": "4360838", "title": "Prolactin receptors in mammary carcinoma cells.", "content": "Prolactin receptors in mammary carcinoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360838"}
{"pmid": "4360840", "title": "The enzymology of methionine metabolism in rat hepatomas.", "content": "The enzymology of methionine metabolism in rat hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360840"}
{"pmid": "4360841", "title": "Sites of synthesis of murine RNA tumor virus (oncornavirus) group-specific antigens.", "content": "Sites of synthesis of murine RNA tumor virus (oncornavirus) group-specific antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360841"}
{"pmid": "4360839", "title": "Strain- and age-dependent transplacental carcinogenesis by 1-ethyl-1-nitrosourea in inbred strains of mice.", "content": "Strain- and age-dependent transplacental carcinogenesis by 1-ethyl-1-nitrosourea in inbred strains of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360839"}
{"pmid": "4360842", "title": "Sensitivity of transformed and nontransformed cells to amphotericin B and several rifamycin derivatives.", "content": "Sensitivity of transformed and nontransformed cells to amphotericin B and several rifamycin derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360842"}
{"pmid": "4360843", "title": "Thioacetamide-induced alterations in nuclear RNA transport.", "content": "Thioacetamide-induced alterations in nuclear RNA transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360843"}
{"pmid": "4360833", "title": "The temperature dependency of cochlear adaptation and masking in the guinea pig.", "content": "The temperature dependency of cochlear adaptation and masking in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360833"}
{"pmid": "4360844", "title": "Mitochondrial membrane-associated properties of Morris hepatomas.", "content": "Mitochondrial membrane-associated properties of Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360844"}
{"pmid": "4360847", "title": "The cryptophthalmos-syndactyly syndrome. Description, manner of inheritance, and notes on the eye lesions.", "content": "The cryptophthalmos-syndactyly syndrome. Description, manner of inheritance, and notes on the eye lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360847"}
{"pmid": "4360845", "title": "Studies on the relationship between infection with bovine C-type virus, leukemia, and persistent lymphocytosis in cattle.", "content": "Studies on the relationship between infection with bovine C-type virus, leukemia, and persistent lymphocytosis in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360845"}
{"pmid": "4360848", "title": "Membranous conjunctivitis due to adenovirus type 7 infection.", "content": "Membranous conjunctivitis due to adenovirus type 7 infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360848"}
{"pmid": "4360849", "title": "Schistosoma mansoni: ultrastructural observations on the small intestine of murine host.", "content": "Schistosoma mansoni: ultrastructural observations on the small intestine of murine host.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360849"}
{"pmid": "4360854", "title": "Ectopic ACTH production in carcinoma of the lung.", "content": "Ectopic ACTH production in carcinoma of the lung. Immunoreactive ACTH was found in almost all tissue extracts of lung carcinoma from patients without clinical evidence of Cushing's syndrome; i.e. 14 of 15 primary tumors, nine of nine metastatic lymph nodes, and four of four metastatic liver nodules contained immunoreactive ACTH. The incidence of ACTH in extracts of other tumor types was much lower. Comparable normal tissues contained no detectable ACTH. Immunoreactive growth hormone, parathyroid hormone, or gastrin was not found in the same carcinoma tissue. The predominant form of ACTH in the tumor extracts was big ACTH. In pituitary extracts little ACTH predominated.53% of 83 patients with lung carcinoma had afternoon plasma ACTH levels greater than 150 pg/ml; more than 90% of plasmas containing less than 150 pg/ml were obtained from patients who had received radiation therapy or chemotherapy. 31% of 45 patients with chronic obstructive pulmonary disease (COPD), 28% of 25 patients with other severe lung disease, and 6% of 33 controls had elevated values. Big ACTH predominated in the plasma of patients with lung carcinoma or COPD having elevated ACTH levels. Tissue from the lung of a smoking dog with atypical histologic changes contained immunoreactive ACTH, almost exclusively in the big form, while tissue from another smoking dog that was histologically normal contained no ACTH. Thus ACTH may be present even in precancerous lung lesions. These studies suggest that serial plasma ACTH levels may be of value in screening for, and/or management of, patients with carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360854"}
{"pmid": "4360855", "title": "Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters.", "content": "Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters. Although the usual diet may contain 150-250 mg of plant sterols, chiefly beta-sitosterol, only trace amounts of these sterols have heretofore been found in human or animal blood and tissues. We now report elevated plant sterol levels in the blood and tissues of two sisters with extensive tendon xanthomas but normal plasma cholesterol levels. Besides beta-sitosterolemia and xanthomatosis, no other physical, mental, or biochemical abnormalities were detected.Repeatedly, the plasmas of the two sisters have contained 27.1 and 17.7 mg/100 ml of beta-sitosterol, 9.7 and 8.2 mg/100 ml of campesterol, and 0.5 and 0.5 mg/100 ml of stigmasterol, respectively. These plant sterols constituted 15.6 and 11.3% of the total plasma sterols. Some 60% of the plasma beta-sitosterol and campesterol was esterified; the measurable stigmasterol was entirely unesterified. The transport of the plasma beta-sitosterol and campesterol was largely in low density lipoproteins (76 and 83%, respectively). High density lipoproteins carried the remainder. Plant sterols were barely detectable in the very low density lipoprotein fraction. Only trace amounts of stigmasterol could be detected in the low density and high density lipoprotein fractions. The plant sterol content of the red blood cells averaged 12-13 mg/100 ml packed cells or about 13% of the total sterols. Two tendon xanthoma biopsies with the usual high concentration of cholesterol had 36.7 and 4.0 mg of plant sterols/g dry wt, of which 25.7 and 2.9 mg were beta-sitosterol, entirely in the free form. Plant sterols were also found in adipose tissue (0.2 mg/g wet wt) and in skin surface lipids (3.2 mg/g of lipid). The intestinal absorption of beta-sitosterol in both the patients, measured by two techniques, indicated greatly increased absorption of this sterol (about 24 and 28% in the patients L. H. and R. H., respectively, normal absorption being <5%). We suggest that increased absorption of beta-sitosterol must be considered as one cause of this disease. The reason for the extensive xanthomatosis in these two patients remains unknown. Perhaps in some way plant sterols initiated the development of xanthomas with otherwise normal plasma cholesterol levels. Clinical atherosclerosis has not yet occurred. The occurrence of beta-sitosterolemia in these two sisters with un-affected parents suggests an inherited recessive trait.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360855"}
{"pmid": "4360857", "title": "The mechanism of activation of hormone-sensitive lipase in human adipose tissue.", "content": "The mechanism of activation of hormone-sensitive lipase in human adipose tissue. A partially purified hormone-sensitive triglyceride lipase of human adipose tissue was found to be activated twofold by the addition of cyclic 3',5'-AMP, ATP, and magnesium ions. Lipase activities against diolein and monoolein were not affected. Addition of protein kinase inhibitor at zero time completely inhibited activation, and this inhibition was prevented by prior addition of an excess of exogenous protein kinase (from rabbit skeletal muscle). Addition of protein kinase inhibitor during the activation step blocked the activation process without a time lag, suggesting that protein kinase operates directly on hormone-sensitive lipase. Further purification yielded a fraction free of protein kinase, and lipase activation in this fraction depended absolutely on addition of exogenous kinase. Incubation of human fat with epinephrine or isoproterenol stimulated lipolysis and caused conversion of nonactivated hormone-sensitive lipase to its activated form, as indicated by a decrease in the activation subsequently obtainable in fractions prepared from such hormone-treated tissues. These findings strongly suggest that the stimulation of lipolysis by hormonal treatment is the consequence of the activation of hormone-sensitive triglyceride lipase by cyclic 3',5'-AMP-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360857"}
{"pmid": "4360856", "title": "On the mechanism of lithium-induced diabetes insipidus in man and the rat.", "content": "On the mechanism of lithium-induced diabetes insipidus in man and the rat. The mechanism of lithium-induced diabetes insipidus was investigated in 96 patients and in a rat model. Polydipsia was reported by 40% and polyuria (more than 3 liter/day) by 12% of patients receiving lithium. Maximum concentrating ability after dehydration and vasopressin was markedly impaired in 10 polyuric patients and was reduced in 7 of 10 nonpolyuric patients studied before and during lithium therapy. Severe polyuria (more than 6 liter/day) was unresponsive to trials of vasopressin and chlorpropamide, but improved on chlorothiazide. Rats receiving lithium (3-4 meq/kg/day) developed massive polyuria that was resistant to vasopressin, in comparison to rats with comparable polyuria induced by drinking glucose. Analysis of renal tissue in rats with lithium polyuria showed progressive increase in the concentration of lithium from cortex to papilla with a 2.9-fold corticopapillary gradient for lithium. The normal corticopapillary gradient for sodium was not reduced by lithium treatment. The polyuria was not interrupted by brief intravenous doses of vasopressin (5-10 mU/kg) or dibutyryl cyclic AMP (10-15 mg/kg) capable of reversing water diuresis in normal and hypothalamic diabetes insipidus rats (Brattleboro strain). The present studies suggest that nephrogenic diabetes insipidus is a common finding after lithium treatment and results in part from interference with the mediation of vasopressin at a step distal to the formation of 3',5' cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360856"}
{"pmid": "4360859", "title": "A specific role for saline or the sodium ion in the regulation of renin and aldosterone secretion.", "content": "A specific role for saline or the sodium ion in the regulation of renin and aldosterone secretion. It is well established that in normal man the renin-angiotensin-aldosterone system is responsive to changes in volume. The present study was performed to determine whether sodium has an action apart from volume in the regulation of the secretion of renin and aldosterone. Acute volume expansion was induced either by saline, dextran, or glucose infusion in supine, normal subjects in balance on a 10 meq sodium/100 meq potassium diet. Plasma renin activity (PRA), angiotensin II (A II), aldosterone (PA), cortisol, serum sodium, and potassium were measured every 10 min for the first 30 min and then at 1, 2, 4, 6, and 8 h. During saline infusion (500 cm(3)/h for 6 h) mean PRA and A II levels declined very rapidly, falling significantly below control at 10 min (P < 0.01) and by 50% at 60 min. Thereafter, the rate of fall was more gradual, reaching a nadir at 360 min (70-80% below control). PA declined in a parallel pattern except that a significant fall did not occur until 30 min. In contrast to saline, dextran infusion (250 cm(3)/h for 4 h) did not produce a significant fall in PRA, A II, or PA until 4 h after the start of the infusion despite equivalent volume expansion. On the other hand, the infusion of 5% glucose and water (500 cm(3)/h for 6 h) did not produce a significant decline in PRA, A II, or PA over the first 6 h of the study. Although the response rate of PRA, A II, and PA was different in each of the three infusion studies, these parameters were significantly correlated within each study. Serum sodium and potassium levels did not change during any study except dextran infusion, where a significant fall in both occurred at 120 min. In all the infusion studies, plasma cortisol levels gradually declined during the 8-h study period consistent with its expected rhythm of diurnal secretion. These results demonstrate that rate of response of the renin-angiotensin-aldosterone system to acute volume expansion with saline differed from that with dextran and glucose infusion in sodium-depleted man. The data support a specific role for volume expansion with saline or the sodium ion per se in the regulation of renin and aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360859"}
{"pmid": "4360861", "title": "Genetic control of the immune response: the effect of non-H-2 linked genes on antibody production.", "content": "Genetic control of the immune response: the effect of non-H-2 linked genes on antibody production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360861"}
{"pmid": "4360860", "title": "Studies on the effect of specific antisera on the metabolism of cellular antigens. II. The synthesis and degradation of TL antigens of mouse cells in the presence of TL antiserum.", "content": "Studies on the effect of specific antisera on the metabolism of cellular antigens. II. The synthesis and degradation of TL antigens of mouse cells in the presence of TL antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360860"}
{"pmid": "4360858", "title": "Sequence of events mediating the effect of cholera toxin on rat thymocytes.", "content": "Sequence of events mediating the effect of cholera toxin on rat thymocytes. We have found that in rat thymocytes binding of [(125)I]choleragen is followed by cellular accumulation of cyclic 3',5'-AMP which, in turn, is followed by stimulation of amino acid transport. Binding of cholera toxin was complete by 30 min and remained constant for the subsequent 150 min. After stimulation by choleragen, cellular cyclic 3',5'-AMP became maximal by 30 min, after which it declined steadily so that by 90 min of incubation, cellular cyclic nucleotide levels were only 20% of those seen at 30 min. Stimulation of amino acid transport, although detectable by 15 min, did not become maximal until 120 min (by which time cellular cyclic 3',5'-AMP had decreased by more than 80%). We have also used this system to delineate the step at which various pharmacologic agents and hormones act to alter the sequence of events mediating the response of rat thymocytes to cholera toxin. The ability of cycloheximide to abolish choleragen-stimulated amino acid influx without reducing [(125)I]choleragen binding or cellular cyclic 3',5'-AMP suggests that cyclic nucleotide stimulation of amino acid transport includes a step involving protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360858"}
{"pmid": "4360862", "title": "Comparative in vitro studies on effector cell diversity in the cellular immune response to murine sarcoma virus (MSV)-induced tumors in mice.", "content": "Comparative in vitro studies on effector cell diversity in the cellular immune response to murine sarcoma virus (MSV)-induced tumors in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360862"}
{"pmid": "4360863", "title": "The characteristics of a circulating antigen in schistosomiasis.", "content": "The characteristics of a circulating antigen in schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360863"}
{"pmid": "4360865", "title": "Metabolic bone disease--recent developments.", "content": "Metabolic bone disease--recent developments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360865"}
{"pmid": "4360866", "title": "Provocative tests of the hypothalamic-anterior pituitary-target organ axis.", "content": "Provocative tests of the hypothalamic-anterior pituitary-target organ axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360866"}
{"pmid": "4360867", "title": "The enterohormones. Current status and review.", "content": "The enterohormones. Current status and review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360867"}
{"pmid": "4360864", "title": "Cancer and ectopic hormones.", "content": "Cancer and ectopic hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360864"}
{"pmid": "4360853", "title": "Multidisciplinary teams develop programming for patient education.", "content": "Multidisciplinary teams develop programming for patient education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360853"}
{"pmid": "4360868", "title": "Biochemistry of cancer cells: focus on the cell surface.", "content": "Biochemistry of cancer cells: focus on the cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360868"}
{"pmid": "4360872", "title": "Toxoplasmosis: a review.", "content": "Toxoplasmosis: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360872"}
{"pmid": "4360874", "title": "Nucleus gracilis responses to knee joint motion: a frequency response study.", "content": "Nucleus gracilis responses to knee joint motion: a frequency response study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360874"}
{"pmid": "4360875", "title": "Statistical properties of neurons in the rat mesencephalic reticular formation.", "content": "Statistical properties of neurons in the rat mesencephalic reticular formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360875"}
{"pmid": "4360878", "title": "Reward-associated inhibition and pain-associated excitation lasting seconds in single intralaminar thalamic units.", "content": "Reward-associated inhibition and pain-associated excitation lasting seconds in single intralaminar thalamic units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360878"}
{"pmid": "4360876", "title": "Presynaptic depolarization and extracellular potassium in the cat lateral geniculate nucleus.", "content": "Presynaptic depolarization and extracellular potassium in the cat lateral geniculate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360876"}
{"pmid": "4360877", "title": "Hippocampal suppression of intralaminar thalamic unit responses in cats and comparison with suppression evoked from the caudate nucleus.", "content": "Hippocampal suppression of intralaminar thalamic unit responses in cats and comparison with suppression evoked from the caudate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360877"}
{"pmid": "4360880", "title": "Dissecting a short-term memory circuit in the rat brain. I. Changes in entorhinal unit activity and responsiveness of hippocampal units in the process of classical conditioning.", "content": "Dissecting a short-term memory circuit in the rat brain. I. Changes in entorhinal unit activity and responsiveness of hippocampal units in the process of classical conditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360880"}
{"pmid": "4360881", "title": "Discharge characteristics of neurons in anteroventral and dorsal cochlear nuclei of cat.", "content": "Discharge characteristics of neurons in anteroventral and dorsal cochlear nuclei of cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360881"}
{"pmid": "4360882", "title": "Repetitive discharge rate of a simple neuron model with accumulation of after-hyperpolarization conductance.", "content": "Repetitive discharge rate of a simple neuron model with accumulation of after-hyperpolarization conductance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360882"}
{"pmid": "4360883", "title": "Spontaneous activity of single neurons in the precruciate area of the cat's sensory motor cortex.", "content": "Spontaneous activity of single neurons in the precruciate area of the cat's sensory motor cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360883"}
{"pmid": "4360884", "title": "Effects of excitants on neurones and cerebellar-evoked field potentials in the inferior olivary complex of the rat.", "content": "Effects of excitants on neurones and cerebellar-evoked field potentials in the inferior olivary complex of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360884"}
{"pmid": "4360885", "title": "Responses of spinal cord neurons to graded noxious and non-noxious stimuli.", "content": "Responses of spinal cord neurons to graded noxious and non-noxious stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360885"}
{"pmid": "4360886", "title": "Correlation of latency to drink and unit activity following cholinergic stimulation of medial septal nucleus in rats.", "content": "Correlation of latency to drink and unit activity following cholinergic stimulation of medial septal nucleus in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360886"}
{"pmid": "4360888", "title": "Distribution of carotid body chemoreceptor afferents in the medulla of the cat.", "content": "Distribution of carotid body chemoreceptor afferents in the medulla of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360888"}
{"pmid": "4360887", "title": "Projection of tooth pulp afferents in the brain stem of rhesus monkey.", "content": "Projection of tooth pulp afferents in the brain stem of rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360887"}
{"pmid": "4360889", "title": "Caudate-evoked inhibition and actions of GABA and other substances on cat pallidal neurons.", "content": "Caudate-evoked inhibition and actions of GABA and other substances on cat pallidal neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360889"}
{"pmid": "4360890", "title": "Depression by p-methoxyphenylethylamine of sympathetic reflex firing elicited by electrical stimulation of the carotid sinus nerve or pelvic nerve.", "content": "Depression by p-methoxyphenylethylamine of sympathetic reflex firing elicited by electrical stimulation of the carotid sinus nerve or pelvic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360890"}
{"pmid": "4360891", "title": "The effect of intracochlearly administered acetylcholine-blocking agents on the efferent synapses of the cochlea.", "content": "The effect of intracochlearly administered acetylcholine-blocking agents on the efferent synapses of the cochlea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360891"}
{"pmid": "4360893", "title": "Somatosensory properties of neurons in the superior parietal cortex (area 5) of the rhesus monkey.", "content": "Somatosensory properties of neurons in the superior parietal cortex (area 5) of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360893"}
{"pmid": "4360894", "title": "Effect of gamma rays and some chemical mutagens on induction of telotrisomics in Hordeum.", "content": "Effect of gamma rays and some chemical mutagens on induction of telotrisomics in Hordeum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360894"}
{"pmid": "4360895", "title": "The repair of methyl methanesulphonate-induced lesions in the DNA of a murine lymphoma cell.", "content": "The repair of methyl methanesulphonate-induced lesions in the DNA of a murine lymphoma cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360895"}
{"pmid": "4360896", "title": "Separation and characterization of polypeptides from the venom of Dendroaspis viridis.", "content": "Separation and characterization of polypeptides from the venom of Dendroaspis viridis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360896"}
{"pmid": "4360892", "title": "Visual and somatosensory receptive fields of neurons in the squirrel monkey pulvinar.", "content": "Visual and somatosensory receptive fields of neurons in the squirrel monkey pulvinar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360892"}
{"pmid": "4360898", "title": "Hormonal regulation of cyclic-AMP-dependent protein kinase of rat diaphragm by epinephrine and insulin.", "content": "Hormonal regulation of cyclic-AMP-dependent protein kinase of rat diaphragm by epinephrine and insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360898"}
{"pmid": "4360899", "title": "Thiophosphate-analogues and 1-N-oxides of ATP and ADP in mitochondrial translocation and phosphoryl-transfer reactions.", "content": "Thiophosphate-analogues and 1-N-oxides of ATP and ADP in mitochondrial translocation and phosphoryl-transfer reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360899"}
{"pmid": "4360901", "title": "Preparation of the enzymatically active subfragment of myosin by proteolysis of myofibrils.", "content": "Preparation of the enzymatically active subfragment of myosin by proteolysis of myofibrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360901"}
{"pmid": "4360902", "title": "Studies of glutamate dehydrogenase. The interaction of glutamate dehydrogenase with alpha-NADH.", "content": "Studies of glutamate dehydrogenase. The interaction of glutamate dehydrogenase with alpha-NADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360902"}
{"pmid": "4360900", "title": "Correlations between structure and spectroscopic properties in membrane model system. Fluorescence and circular dichroism of the cytochrome c-cardiolipin system.", "content": "Correlations between structure and spectroscopic properties in membrane model system. Fluorescence and circular dichroism of the cytochrome c-cardiolipin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360900"}
{"pmid": "4360904", "title": "Subunit structure of aspartokinase 3 of Escherichia coli K12.", "content": "Subunit structure of aspartokinase 3 of Escherichia coli K12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360904"}
{"pmid": "4360905", "title": "Studies on thymus products. VI. The effects of cyclic nucleotides and prostaglandins on rosette-forming cells. Interactions with thymic factor.", "content": "Studies on thymus products. VI. The effects of cyclic nucleotides and prostaglandins on rosette-forming cells. Interactions with thymic factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360905"}
{"pmid": "4360906", "title": "Cyclic AMP-mediated stimulation by calcium of thymocyte proliferation.", "content": "Cyclic AMP-mediated stimulation by calcium of thymocyte proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360906"}
{"pmid": "4360907", "title": "Control of DNA replication in Physarum polycephalum. I. Specific activity of NAD pyrophosphorylase in isolated nuclei during the cell cycle.", "content": "Control of DNA replication in Physarum polycephalum. I. Specific activity of NAD pyrophosphorylase in isolated nuclei during the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360907"}
{"pmid": "4360909", "title": "Mutant human fibroblast clones able to grow on homocysteine instead of cyst(e)ine.", "content": "Mutant human fibroblast clones able to grow on homocysteine instead of cyst(e)ine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360909"}
{"pmid": "4360908", "title": "Depression of RNA synthesis in the prematurely condensed chromatin of pulverized HeLa cells.", "content": "Depression of RNA synthesis in the prematurely condensed chromatin of pulverized HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360908"}
{"pmid": "4360910", "title": "Immune microfluorimetric analysis of the distribution of species specific nuclear antigens in HeLa-chick erythrocyte heterokaryons.", "content": "Immune microfluorimetric analysis of the distribution of species specific nuclear antigens in HeLa-chick erythrocyte heterokaryons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360910"}
{"pmid": "4360911", "title": "Radiation-induced DNA synthesis in nuclei of hen erythrocytes reactivated in heterokaryons.", "content": "Radiation-induced DNA synthesis in nuclei of hen erythrocytes reactivated in heterokaryons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360911"}
{"pmid": "4360912", "title": "Comparative activities of mammalian, reptilian, and piscine gonadotropins in monkey granulosa cell cultures.", "content": "Comparative activities of mammalian, reptilian, and piscine gonadotropins in monkey granulosa cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360912"}
{"pmid": "4360914", "title": "The control of adrenocortical secretion in the brush-tailed possum, Trichosurus vulpecula.", "content": "The control of adrenocortical secretion in the brush-tailed possum, Trichosurus vulpecula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360914"}
{"pmid": "4360915", "title": "Sleep induced by spinal cord cholinergic stimulation.", "content": "Sleep induced by spinal cord cholinergic stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360915"}
{"pmid": "4360917", "title": "Remission of acanthosis nigricans associated with polycystic ovarian disease and a stromal luteoma.", "content": "Remission of acanthosis nigricans associated with polycystic ovarian disease and a stromal luteoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360917"}
{"pmid": "4360913", "title": "Ovarian maintenance in the hypophysectomized catfish, Heteropneustes fossilis (Bloch), with mammalian hypophyseal and placental hormones, and gonadal and adrenocortical steroids.", "content": "Ovarian maintenance in the hypophysectomized catfish, Heteropneustes fossilis (Bloch), with mammalian hypophyseal and placental hormones, and gonadal and adrenocortical steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360913"}
{"pmid": "4360918", "title": "Secretion and metabolic efficacy of parthyroid hormone in patients with severe hypomagnesemia.", "content": "Secretion and metabolic efficacy of parthyroid hormone in patients with severe hypomagnesemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360918"}
{"pmid": "4360919", "title": "Steroid production from plasma cholesterol. II. In vivo conversion of plasma cholesterol to ovarian progesterone and adrenal C19 and C21 steroids in humans.", "content": "Steroid production from plasma cholesterol. II. In vivo conversion of plasma cholesterol to ovarian progesterone and adrenal C19 and C21 steroids in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360919"}
{"pmid": "4360920", "title": "Integrated concentrations of growth hormone correlated with stage of puberty and estrogen levels in girls.", "content": "Integrated concentrations of growth hormone correlated with stage of puberty and estrogen levels in girls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360920"}
{"pmid": "4360921", "title": "Uptake of iodinated human chorionic gonadotropin by monkey ovaries in vivo.", "content": "Uptake of iodinated human chorionic gonadotropin by monkey ovaries in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360921"}
{"pmid": "4360922", "title": "Pregnenolone in man: plasma levels in states of normal and abnormal steroidogenesis.", "content": "Pregnenolone in man: plasma levels in states of normal and abnormal steroidogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360922"}
{"pmid": "4360923", "title": "Protection by pregnancy. Zollinger-Ellison syndrome.", "content": "Protection by pregnancy. Zollinger-Ellison syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360923"}
{"pmid": "4360916", "title": "Ascorbate oxidase. New method of purification of the enzyme from green zucchini squash and identity of its copper moiety with that of cucumber ascorbate oxidase.", "content": "Ascorbate oxidase. New method of purification of the enzyme from green zucchini squash and identity of its copper moiety with that of cucumber ascorbate oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360916"}
{"pmid": "4360926", "title": "Extracellular current density analysis of responses in cerebellar cortex to climbing fiber activation.", "content": "Extracellular current density analysis of responses in cerebellar cortex to climbing fiber activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360926"}
{"pmid": "4360925", "title": "Local vesicle populations in rat superior cervical ganglia and the vesicle hypothesis.", "content": "Local vesicle populations in rat superior cervical ganglia and the vesicle hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360925"}
{"pmid": "4360927", "title": "Evidence that cyclic AMP is not the chemical mediator of the metabolic changes accompanying phagocytosis.", "content": "Evidence that cyclic AMP is not the chemical mediator of the metabolic changes accompanying phagocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360927"}
{"pmid": "4360924", "title": "The relationship between ATP and an electrogenic pump in the plasma membrane of Neurospora crassa.", "content": "The relationship between ATP and an electrogenic pump in the plasma membrane of Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360924"}
{"pmid": "4360929", "title": "Some inferences from galactokinase deficiency.", "content": "Some inferences from galactokinase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360929"}
{"pmid": "4360928", "title": "The pathogenesis of anuria following shock.", "content": "The pathogenesis of anuria following shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360928"}
{"pmid": "4360930", "title": "Galactokinase deficiency in twins: clinical and biochemical studies.", "content": "Galactokinase deficiency in twins: clinical and biochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360930"}
{"pmid": "4360931", "title": "Infectious mononucleosis and Epstein-Barr virus in childhood.", "content": "Infectious mononucleosis and Epstein-Barr virus in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360931"}
{"pmid": "4360932", "title": "\"Typus Edinburgensis\"?", "content": "\"Typus Edinburgensis\"?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360932"}
{"pmid": "4360934", "title": "Multiple activities of DNA polymerase from visna virus.", "content": "Multiple activities of DNA polymerase from visna virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360934"}
{"pmid": "4360935", "title": "The association of herpesvirus type 2 infection and cervical cancer.", "content": "The association of herpesvirus type 2 infection and cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360935"}
{"pmid": "4360936", "title": "Genetic economy of polyoma virus: capsid proteins are cleavage products of same viral gene.", "content": "Genetic economy of polyoma virus: capsid proteins are cleavage products of same viral gene. Two-dimensional tryptic peptide maps of the nonhistone proteins of purified polyoma virus show marked similarities. Protein P(1) is a nondisaggregated, possibly covalent, dimer of the major capsid protein P(2), whereas P(3) and P(4) share several new peptides as well as many of the peptides derived from P(2). Extensive use of this kind of processing of viral proteins during the biosynthesis of DNA-containing animal viruses has not been reported previously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360936"}
{"pmid": "4360938", "title": "Cell-free translation of messenger RNA of simian virus 40: synthesis of the major capsid protein.", "content": "Cell-free translation of messenger RNA of simian virus 40: synthesis of the major capsid protein. Extracts of wheat germ are capable of synthesizing the major capsid protein of simian virus 40. Poly(A)-containing RNA from BS-C-1 cells infected with simian virus 40 directed the synthesis of a novel polypeptide that migrates in polyacrylamide gels together with the major capsid polypeptide of simian virus 40, VP-1. The patterns of the major tryptic peptides of purified VP-1 and the novel polypeptide synthesized in vitro were identical after two-dimensional paper electrophoresis. The novel polypeptide was not synthesized in response to poly(A)-rich RNA from uninfected cells or from virus-infected cells treated with cytosine arabinoside. Messenger RNA from infected cells purified by selective hybridization to DNA of simian virus 40 directs the synthesis of a major polypeptide of electrophoretic mobility similar to that of VP-1 of simian virus 40. This approach should prove useful in identifying additional products specified by DNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360938"}
{"pmid": "4360933", "title": "The influence of N6-2'-O-dibutyryl cyclic 3',5'-AMP on the metabolism of cholesterol-26-14C and cholesterol-4-14C in the rats fed on atherogenic or lipid-rich diet.", "content": "The influence of N6-2'-O-dibutyryl cyclic 3',5'-AMP on the metabolism of cholesterol-26-14C and cholesterol-4-14C in the rats fed on atherogenic or lipid-rich diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360933"}
{"pmid": "4360939", "title": "Specific binding of cholera toxin to isolated intestinal microvillous membranes.", "content": "Specific binding of cholera toxin to isolated intestinal microvillous membranes. A sucrose density gradient assay was used to demonstrate the specificity and saturation of the binding of [(125)I]cholera toxin to isolated intestinal microvillous membranes from rat small intestine. When the toxin is first complexed to antitoxin and then exposed to intestinal membranes, the binding of cholera toxin is inhibited. To emphasize the physiologic importance of these observations, similar concentrations of [(125)I]cholera toxin were shown to stimulate the accumulation of cyclic AMP in mucosal homogenates and to increase the secretion of fluid into intestinal loops, whereas the same concentrations of toxin mixed with antitoxin had no effect on cyclic AMP accumulation. These studies suggest that cholera toxin attaches to brush border binding sites before exerting its biologic effect and that local intestinal antibody protection against cholera toxin may be due to inhibition of toxin attachment to these binding sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360939"}
{"pmid": "4360940", "title": "Inhibition of induced aldosterone biosynthesis with a specific antagonist of angiotensin II.", "content": "Inhibition of induced aldosterone biosynthesis with a specific antagonist of angiotensin II. The present study determined the effect of [Sar(1)-Ile(8)]-angiotensin II on steroidogenesis and induced aldosterone synthesis by the octapeptide angiotensin II, the heptapeptide des-Asp(1)-angiotensin II, and adrenocorticotropic hormone. Rabbit adrenal cells were suspended by incubation of the capsular cortical tissue with collagenase, and aldosterone levels were determined by immunoassay. Steroidogenic responses to angiotensin II and des-Asp(1)-angiotensin were essentially the same. [Sar(1)-Ile(8)]-angiotensin II (10(-7) to 5 x 10(-7) M) had no significant effect on basal aldosterone biosynthesis. However, when added with steroidogenic peptides, it completely blocked the effect of angiotensin II and des-Asp(1)-angiotensin II but not of adrenocorticotropic hormone. The dose ratio of the antagonist to angiotensin II that gave 100% inhibition was about 2:1 and to des-Asp(1)-angiotensin II, about 50:1. The data suggest that des-Asp(1)-angiotensin II has a much higher affinity for the angiotensin receptor in adrenal cortex than angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360940"}
{"pmid": "4360941", "title": "Homology between Burkitt herpes viral DNA and DNA in continuous lymphoblastoid cells from patients with infectious mononucleosis.", "content": "Homology between Burkitt herpes viral DNA and DNA in continuous lymphoblastoid cells from patients with infectious mononucleosis. At least 90% of the sequences of purified, in vitro labeled, DNA from Epstein-Barr virus (prepared from HR-1, Burkitt's lymphoblastoid cells) are homologous to the DNA of the herpes virus contained in cell lines derived from patients with infectious mononucleosis. The thermal stability of the homologous and heterologous hybrid DNA molecules could not be differentiated, indicating at least 97% matching of base pairs between DNA of Epstein-Barr virus and the herpes viral DNA contained in the lymphoblasts from patients with infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360941"}
{"pmid": "4360942", "title": "Nucleotide sequences of RNA transcribed in infected cells and by Escherichia coli RNA polymerase from a segment of simian virus 40 DNA.", "content": "Nucleotide sequences of RNA transcribed in infected cells and by Escherichia coli RNA polymerase from a segment of simian virus 40 DNA. The nucleotide sequence of 180 residues of an RNA transcript of DNA of simian virus 40 has been deduced. This sequence adjoins a preferred initiation site for E. coli RNA polymerase. Comparison of this sequence with that of complementary RNA of simian virus 40 from infected cells has shown that this site also adjoins the apparent 3' terminus of some of the cytoplasmic complementary RNA of simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360942"}
{"pmid": "4360937", "title": "Absence of a specific ganglioside galactosyltransferase in mouse cells transformed by murine sarcoma virus.", "content": "Absence of a specific ganglioside galactosyltransferase in mouse cells transformed by murine sarcoma virus. The ganglioside composition of a nonproducer subclone (derived from BALB/c 3T3 mouseembryo cells) transformed by Kirsten murine sarcoma virus was drastically altered compared to the nontransformed parental clone. The transformed clone was unable to synthesize the mono- and disialogangliosides, G(M1) and G(D1a), due to the complete absence of a specific galactosyltransferase. The lack of this enzyme activity was established by sensitive radiochemical and enzymological techniques in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360937"}
{"pmid": "4360944", "title": "Translational diffusion coefficient and partition coefficient of a spin-labeled solute in lecithin bilayer membranes.", "content": "Translational diffusion coefficient and partition coefficient of a spin-labeled solute in lecithin bilayer membranes. The translational diffusion coefficient and the partition coefficient of a spin-labeled solute, di-t-butyl nitroxide, in an aqueous suspension of dipalmitoyl lecithin vesicles have been studied by electron spin resonance spectroscopy. When the lecithin is cooled through its phase transition temperature near 41 degrees C, some solute is \"frozen out\" of the bilayer, and the standard partial molar enthalpy and entropy of partition go more positive by a factor of 8 and 6, respectively. However, the apparent diffusion constant in the lecithin phase is only slightly smaller than that in water, both above and below the transition temperature. The fraction of bilayer volume within which solute is distributed may increase with temperature, contributing to the positive enthalpy of partition. Comparison of time constants suggests that there is a permeability barrier to this solute in the periphery of the bilayer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360944"}
{"pmid": "4360943", "title": "Initiation characteristics for the synthesis of five T4 phage-specific messenger RNAs in vitro.", "content": "Initiation characteristics for the synthesis of five T4 phage-specific messenger RNAs in vitro. The involvement of the nucleoside triphosphates in the initiation of the synthesis of the messenger ribonucleic acid of five T4 specific enzymes has been studied. Only one of these, the messenger RNA for deoxynucleosidemonophosphate kinase, can be initiated in the presence of one nucleoside triphosphate, namely ATP. All of the remaining four require the presence of at least two nucleoside triphosphates during the initiation period. The combination of ATP and UTP was best for the initiation of messenger RNA for dihydrofolate reductase, ATP and CTP for deoxycytidylate hydroxymethyltransferase and beta-glucosyltransferase, and ATP and GTP for alpha-glucosyltransferase. We have concluded that there is a great variation in the nucleotide composition and sequence of the initiation sites in T4 DNA. No correlation in the requirements of nucleoside triphosphates during the initiation period could be observed among the five systems studied according to their classification as one type or another of \"early\" T4 messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360943"}
{"pmid": "4360946", "title": "A comparison of membrane proteins of normal and transformed cells by lactoperoxidase labeling.", "content": "A comparison of membrane proteins of normal and transformed cells by lactoperoxidase labeling. The enzyme lactoperoxidase (iodide:hydrogen-peroxide oxidoreductase, EC 1.11.1.8) was used to iodinate ((125)I) accessible proteins on membranes of intact virally transformed and untransformed cells. A number of labeled bands of proteins were detected by acrylamide gel electrophoresis. A heavily labeled band with a molecular weight of approximately 250,000 daltons was found in all untransformed cells but was absent from transformed cells. When Coomassie-blue-stained membrane preparations were compared, a band was seen in normal cells which co-migrated with the lactoperoxidase-labeled band. In transformed cell membranes, three discrete bands were present in the same position. Thus, the expression of this protein may be altered when cells are in the transformed state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360946"}
{"pmid": "4360947", "title": "Multiple regulation of the galactose operon-genetic evidence for a distinct site in the galactose operon that responds to capR gene regulation in Escherichia coli K-12.", "content": "Multiple regulation of the galactose operon-genetic evidence for a distinct site in the galactose operon that responds to capR gene regulation in Escherichia coli K-12. Previous results demonstrated that the capR (lon) locus, which is not linked to the gal operon, independently controls the synthesis of the gal operon enzymes and gal mRNA, i.e., galO(+)capR9 strains are derepressed 4- to 6-fold as compared to galO(+)capR(+) strains. A mutation has been isolated and localized in the galactose operator region that defines a new and distinct site of control. Mutation in this site, designated galO(capR+), causes a 4-fold increase in the galactose enzymes, galactokinase (EC 2.7.1.6) and UDP-galactose-4-epimerase (EC 5.1.3.2), in a capR(+) background. These mutants exhibit a reduced response to regulation by the unlinked regulator gene capR (lon). However, the galO(capR+) mutants are still subject to control by the galR repressor, since they can be further derepressed by growth in the presence of D-fucose. They also synthesize more galactokinase when grown in glycerol as compared to glucose. Thus there are now at least three, and probably four, sites for control of mRNA synthesis in the operator-promoter regions of the gal operon, making it one of the most complex control systems to date for a single operon in bacteria. The complexity is sufficient to accommodate models for differentiation in higher organisms that require more than one \"switch\" to control a single group of genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360947"}
{"pmid": "4360948", "title": "Homeoviscous adaptation--a homeostatic process that regulates the viscosity of membrane lipids in Escherichia coli.", "content": "Homeoviscous adaptation--a homeostatic process that regulates the viscosity of membrane lipids in Escherichia coli. E. coli incorporates increasing proportions of saturated and long-chain fatty acids into phospholipids as growth temperature is increased. It was found that this compositional variation results in the biosynthesis of phospholipids that have identical viscosities at the temperature of growth of the cells. This \"homeoviscous adaptation\" can also be observed in E. coli membrane preparations. Viscosities were determined by use of the electron spin resonance spin-label technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360948"}
{"pmid": "4360950", "title": "Effect of prostaglandins and epinephrine on the level of cyclic AMP-14C of smooth muscle from the rhesus monkey.", "content": "Effect of prostaglandins and epinephrine on the level of cyclic AMP-14C of smooth muscle from the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360950"}
{"pmid": "4360945", "title": "The effect of light on fruiting body formation and adenosine 3':5'-cyclic monophosphate metabolism in Coprinus macrorhizus.", "content": "The effect of light on fruiting body formation and adenosine 3':5'-cyclic monophosphate metabolism in Coprinus macrorhizus. The monokaryotic mycelia of a mutant strain, fis(c), of Coprinus macrorhizus, which are able to form monokaryotic fruiting bodies in the light, failed to form any fruiting bodies in darkness. A dikaryon and a mutant strain, ds, formed malformed fruiting bodies in darkness. Illumination for 1 day of fis(c) mycelia grown in darkness for 4 days or longer was effective in inducing malformed fruiting bodies. The accumulation of adenosine 3':5'-cyclic monophosphate in the illuminated mycelia of strain fis(c) was demonstrated. The illuminated mycelia of strain fis(c) produced high levels of adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] and phosphodiesterase (3':5'-cyclic-AMP 5'-nucleotidohydrolase, EC 3.1.4.17), which degrades cAMP, while the dark-grown mycelia showed no or very low activities of these enzymes. Dikaryotic mycelia and monokaryotic mycelia of strain ds produced significant amounts of these enzymes even in darkness. When the dark-grown mycelia of strain fis(c) were exposed to continuous light, the activities of adenylate cyclase and phosphodiesterase increased rapidly after a lag period whose length depends on the culture age of mycelia. Cycloheximide inhibited the increase in these enzyme activities stimulated by light. When the fis(c) mycelia were exposed to continuous light, an increase in cAMP-binding activity was observed. A possible participation of cAMP in the formation of fruiting bodies in C. macrorhizus is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360945"}
{"pmid": "4360949", "title": "31P nuclear magnetic resonance spectroscopy of native and recombined lipoproteins.", "content": "31P nuclear magnetic resonance spectroscopy of native and recombined lipoproteins. Native and recombined lipoproteins have been studied by (31)P nuclear magnetic resonance spectroscopy. Very low-, low-, and high-density lipoproteins exhibited characteristic spectra. The main resonances were assigned to phosphatidylcholine and sphingomyelin. Relaxation times for these phospholipids were separately measured in low-density lipoproteins and high-density lipoproteins. The effect of paramagnetic ions (Eu(+++)) on the nuclear magnetic resonance spectrum of high-density lipoproteins is reported.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360949"}
{"pmid": "4360951", "title": "Prostaglandin F2 alpha concentration in genital tract secretions of dairy bulls.", "content": "Prostaglandin F2 alpha concentration in genital tract secretions of dairy bulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360951"}
{"pmid": "4360952", "title": "Prostaglandin E2 and its antagonists: effects on autonomic transmission in the isolated sino-atrial node.", "content": "Prostaglandin E2 and its antagonists: effects on autonomic transmission in the isolated sino-atrial node.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360952"}
{"pmid": "4360954", "title": "Enzyme polymorphism and metabolism.", "content": "Enzyme polymorphism and metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360954"}
{"pmid": "4360955", "title": "Prolactin receptors in estrogen receptor-deficient mammary carcinoma.", "content": "Prolactin receptors in estrogen receptor-deficient mammary carcinoma. We demonstrate for the first time the presence of specific high-affinity receptors for prolactin in rat mammayy carcinoma. There appear to be no significant differences between normal rat mammary tissue and the transplantable, estrogen receptor-deficient R3230AC tumor with regard to the number of binding sites, the affinity of the receptor for prolactin, or the specificity of binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360955"}
{"pmid": "4360961", "title": "Deoxyribonuclease in the cow snout epidermis.", "content": "Deoxyribonuclease in the cow snout epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360961"}
{"pmid": "4360953", "title": "Mechanism of action of lithium salts. Biochemical aspects.", "content": "Mechanism of action of lithium salts. Biochemical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360953"}
{"pmid": "4360959", "title": "The role of macrophages in the development of contact sensitivity.", "content": "The role of macrophages in the development of contact sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360959"}
{"pmid": "4360960", "title": "Odland body and intercellular substances.", "content": "Odland body and intercellular substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360960"}
{"pmid": "4360958", "title": "Functional aspects of dermo-epidermal junction.", "content": "Functional aspects of dermo-epidermal junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360958"}
{"pmid": "4360962", "title": "The particulate origin of adenylate kinase isozyme 4.", "content": "The particulate origin of adenylate kinase isozyme 4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360962"}
{"pmid": "4360963", "title": "The role of the renal medulla in hypertension.", "content": "The role of the renal medulla in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360963"}
{"pmid": "4360980", "title": "Virulence of indigenous strains of Entamoeba histolytica in experimental amoebiasis of rats.", "content": "Virulence of indigenous strains of Entamoeba histolytica in experimental amoebiasis of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360980"}
{"pmid": "4360981", "title": "Studies on the effect of lowered temperature on Entamoeba histolytica strains, as  a trial to isolate a strain of the \"Laredo\" type.", "content": "Studies on the effect of lowered temperature on Entamoeba histolytica strains, as  a trial to isolate a strain of the \"Laredo\" type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360981"}
{"pmid": "4360983", "title": "Development of globule leucocyte specific granules from lysosomes.", "content": "Development of globule leucocyte specific granules from lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360983"}
{"pmid": "4360982", "title": "Planning a community mental health program: a case history.", "content": "Planning a community mental health program: a case history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4360982"}
{"pmid": "4361004", "title": "Ultrastructural study of a case of extramammary Paget's disease with special reference to cellular changes in melanocytes and a Langerhans cell.", "content": "Ultrastructural study of a case of extramammary Paget's disease with special reference to cellular changes in melanocytes and a Langerhans cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361004"}
{"pmid": "4361007", "title": "Special observations in skeletal identification.", "content": "Special observations in skeletal identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361007"}
{"pmid": "4361010", "title": "The effect of dibutyryl 3'5'-cyclic AMP on the cardiac pacemaker, arrested with reserpine and alpha-methyl-tyrosine.", "content": "The effect of dibutyryl 3'5'-cyclic AMP on the cardiac pacemaker, arrested with reserpine and alpha-methyl-tyrosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361010"}
{"pmid": "4361013", "title": "Medical management of idiopathic facial (Bell's) palsy.", "content": "Medical management of idiopathic facial (Bell's) palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361013"}
{"pmid": "4361014", "title": "Prostaglandins, cyclic nucleotides and cell function.", "content": "Prostaglandins, cyclic nucleotides and cell function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361014"}
{"pmid": "4361025", "title": "Topological analysis of enzymic mechanisms.", "content": "Topological analysis of enzymic mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361025"}
{"pmid": "4361027", "title": "Pain and suffering. The gate control theory.", "content": "Pain and suffering. The gate control theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361027"}
{"pmid": "4361026", "title": "Power spectra of cortical electric activity in the rabbit in relation to conditioned reflexes.", "content": "Power spectra of cortical electric activity in the rabbit in relation to conditioned reflexes. In chronic experiments on rabbits spectral and correlation characteristics of cerebral cortical potentials were computed to study the elaboration of a conditioned defense reflex. was found that the frequency spectra of the EEG are subject to consistent changes: a narrow-band frequency constantly developing in the theta range. During exposure to a positive conditioned stimulus, the maximum of this frequency increased relative to the pre-stimulus period and a maximal coherence of electrical processes was observed in a narrow theta range between the electrical processes of the cortical analyzers to which the conditional and unconditional stimuli were addressed. Different relationship was noted in the theta range during presentation of a differential or extinguishing stimuli: it became slightly slower than in the pre-stimulus period, and the coherence of the theta rhythms was less than maximal, remaining high at the other frequencies. It was concluded that the presence of highly coherent electrical processes in the theta range is important for the formation of conditioned reflex in the rabbit cerebral cortex. The processes of internal inhibition are characterized electrographically by disagreement of electrical processes in the theta range in respect to phase or frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361026"}
{"pmid": "4361028", "title": "The effects of marijuana on human sleep patterns.", "content": "The effects of marijuana on human sleep patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361028"}
{"pmid": "4361012", "title": "Role of the medial zone of the medulla in rhythmic activity of respiratory center neurons.", "content": "Role of the medial zone of the medulla in rhythmic activity of respiratory center neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361012"}
{"pmid": "4361029", "title": "Urinary tract infection in hospitalized patients.", "content": "Urinary tract infection in hospitalized patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361029"}
{"pmid": "4361022", "title": "Cytochrome c reducing substances in photosynthetic electron transport.", "content": "Cytochrome c reducing substances in photosynthetic electron transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361022"}
{"pmid": "4361031", "title": "Effect of midbrain raphe and lateral mesencephalic stimulation on spontaneous and evoked activity in the lateral geniculate of the cat.", "content": "Effect of midbrain raphe and lateral mesencephalic stimulation on spontaneous and evoked activity in the lateral geniculate of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361031"}
{"pmid": "4361030", "title": "Effects of electrically induced convulsions and transmitter substances on ribonucleic acid turnover in brain slices.", "content": "Effects of electrically induced convulsions and transmitter substances on ribonucleic acid turnover in brain slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361030"}
{"pmid": "4361032", "title": "The effect of electrical stimulation, light and amino acids on the efflux of 35S-taurine from the retina of domestic fowl.", "content": "The effect of electrical stimulation, light and amino acids on the efflux of 35S-taurine from the retina of domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361032"}
{"pmid": "4361033", "title": "Binocular neurons of the rabbit's visual cortex: receptive field characteristics.", "content": "Binocular neurons of the rabbit's visual cortex: receptive field characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361033"}
{"pmid": "4361034", "title": "Binocular neurons of the rabbit's visual cortex: effects of monocular sensory deprivation.", "content": "Binocular neurons of the rabbit's visual cortex: effects of monocular sensory deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361034"}
{"pmid": "4361038", "title": "Studies on the reduction of tetrazolium salts. 3. The products of chemical and enzymic reduction.", "content": "Studies on the reduction of tetrazolium salts. 3. The products of chemical and enzymic reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361038"}
{"pmid": "4361041", "title": "Diagnosis of testicular tumours.", "content": "Diagnosis of testicular tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361041"}
{"pmid": "4361042", "title": "Urinary angiotensinogen loss in chronic proteinuric glomerulonephritis.", "content": "Urinary angiotensinogen loss in chronic proteinuric glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361042"}
{"pmid": "4361043", "title": "Resonance Raman spectra of heme proteins. Effects of oxidation and spin state.", "content": "Resonance Raman spectra of heme proteins. Effects of oxidation and spin state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361043"}
{"pmid": "4361044", "title": "The hydrolysis of penicillin G to 6-amino penicillanic acid by entrapped penicillin acylase.", "content": "The hydrolysis of penicillin G to 6-amino penicillanic acid by entrapped penicillin acylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361044"}
{"pmid": "4361045", "title": "Identification of elastic tissue in human skin viewed in the scanning electron microscope.", "content": "Identification of elastic tissue in human skin viewed in the scanning electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361045"}
{"pmid": "4361046", "title": "Correlations between fatty acid distribution in phospholipids and the temperature dependence of membrane physical state.", "content": "Correlations between fatty acid distribution in phospholipids and the temperature dependence of membrane physical state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361046"}
{"pmid": "4361039", "title": "Biochemical and genetic studies on mammalian cells.", "content": "Biochemical and genetic studies on mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361039"}
{"pmid": "4361047", "title": "A comparison of characteristic temperatures for transport in two unsaturated fatty acid auxotrophs of Escherichia coli.", "content": "A comparison of characteristic temperatures for transport in two unsaturated fatty acid auxotrophs of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361047"}
{"pmid": "4361040", "title": "Isolation and characterization of viruses from fetal calf serum.", "content": "Isolation and characterization of viruses from fetal calf serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361040"}
{"pmid": "4361048", "title": "Electron microscopic observation of the renal lymphatic capillary after injection of ink solution.", "content": "Electron microscopic observation of the renal lymphatic capillary after injection of ink solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361048"}
{"pmid": "4361054", "title": "Adrenaline, DB-c-AMP and myocardial 45Ca exchange. Comparative studies in rat and guinea-pig auricles.", "content": "Adrenaline, DB-c-AMP and myocardial 45Ca exchange. Comparative studies in rat and guinea-pig auricles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361054"}
{"pmid": "4361056", "title": "The effects of 5-hydroxytryptamine and some related compounds on the cat superior cervical ganglion in situ.", "content": "The effects of 5-hydroxytryptamine and some related compounds on the cat superior cervical ganglion in situ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361056"}
{"pmid": "4361057", "title": "Are cholinergic mechanisms involved in morphine effects on motility?", "content": "Are cholinergic mechanisms involved in morphine effects on motility?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361057"}
{"pmid": "4361055", "title": "Stimulatory effects of DB-c-AMP and adrenaline on myocardial contraction and 45Ca exchange. Experiments at reduced calcium concentration and low frequencies of stimulation.", "content": "Stimulatory effects of DB-c-AMP and adrenaline on myocardial contraction and 45Ca exchange. Experiments at reduced calcium concentration and low frequencies of stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361055"}
{"pmid": "4361049", "title": "Pathogenicity of Mokola, a rabies-related virus, in baby mice.", "content": "Pathogenicity of Mokola, a rabies-related virus, in baby mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361049"}
{"pmid": "4361060", "title": "An electron microscope study of the tegument of the metacercaria and adult of Leucochloridiomorpha constantiae (Trematoda: Brachylaemidae).", "content": "An electron microscope study of the tegument of the metacercaria and adult of Leucochloridiomorpha constantiae (Trematoda: Brachylaemidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361060"}
{"pmid": "4361053", "title": "Observations on the frog dorsal column nucleus.", "content": "Observations on the frog dorsal column nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361053"}
{"pmid": "4361061", "title": "Effects of goggle-altered color perception on sleep.", "content": "Effects of goggle-altered color perception on sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361061"}
{"pmid": "4361050", "title": "Neurogenic disorders affecting muscle: five-year analysis of muscle biopsies. I. Segmental atrophy.", "content": "Neurogenic disorders affecting muscle: five-year analysis of muscle biopsies. I. Segmental atrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361050"}
{"pmid": "4361064", "title": "Community control in mental health: how far can it go?", "content": "Community control in mental health: how far can it go?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361064"}
{"pmid": "4361065", "title": "Brief psychotherapy in the hospital setting: techniques and goals.", "content": "Brief psychotherapy in the hospital setting: techniques and goals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361065"}
{"pmid": "4361051", "title": "Chemotherapy of experimental brain tumors: preliminary studies.", "content": "Chemotherapy of experimental brain tumors: preliminary studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361051"}
{"pmid": "4361052", "title": "A new viral-hematologic etiology hypothesis for chronic and paroxysmal headache syndromes.", "content": "A new viral-hematologic etiology hypothesis for chronic and paroxysmal headache syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361052"}
{"pmid": "4361073", "title": "Seasonal change in glycerol kinase activity of goat spermatozoa.", "content": "Seasonal change in glycerol kinase activity of goat spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361073"}
{"pmid": "4361077", "title": "Bronchial carcinoid with choroidal metastasis in an adolescent. Case report and ultrastructural study.", "content": "Bronchial carcinoid with choroidal metastasis in an adolescent. Case report and ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361077"}
{"pmid": "4361076", "title": "Wilms' tumor--a clinical study of eighty-one patients.", "content": "Wilms' tumor--a clinical study of eighty-one patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361076"}
{"pmid": "4361078", "title": "Down's syndrome: establishment of lymphoblastoid cell lines with trisomy 21.", "content": "Down's syndrome: establishment of lymphoblastoid cell lines with trisomy 21.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361078"}
{"pmid": "4361082", "title": "A technique for studying chemotaxis of leucocytes in well-defined chemotactic fields.", "content": "A technique for studying chemotaxis of leucocytes in well-defined chemotactic fields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361082"}
{"pmid": "4361081", "title": "Interspecific somatic cell hybridization between asparagine-requiring and drug-resistant cell lines.", "content": "Interspecific somatic cell hybridization between asparagine-requiring and drug-resistant cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361081"}
{"pmid": "4361083", "title": "Effects of cytochalasin B on cell division and vacuole formation in Tetrahymena pyriformis GL.", "content": "Effects of cytochalasin B on cell division and vacuole formation in Tetrahymena pyriformis GL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361083"}
{"pmid": "4361084", "title": "Unidirectional loss of human chromosomes in rat-human hybrids.", "content": "Unidirectional loss of human chromosomes in rat-human hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361084"}
{"pmid": "4361080", "title": "The deoxyribonucleoside 5'-triphosphate (dATP and dTTP) pool in phytohemagglutinin-stimulated and non-stimulated human lymphocytes.", "content": "The deoxyribonucleoside 5'-triphosphate (dATP and dTTP) pool in phytohemagglutinin-stimulated and non-stimulated human lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361080"}
{"pmid": "4361087", "title": "Comparison of amoebicidal action of antibiotics on Entamoeba histolytica grown axenically & with bacterial or trypanosome associates.", "content": "Comparison of amoebicidal action of antibiotics on Entamoeba histolytica grown axenically & with bacterial or trypanosome associates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361087"}
{"pmid": "4361072", "title": "Action potentials in the cochlea. Masking, adaptation and recruitment.", "content": "Action potentials in the cochlea. Masking, adaptation and recruitment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361072"}
{"pmid": "4361090", "title": "In vitro neoplastic transformation of bovine embryonic urothelium by simian vacuolating virus 40(SV40).", "content": "In vitro neoplastic transformation of bovine embryonic urothelium by simian vacuolating virus 40(SV40).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361090"}
{"pmid": "4361088", "title": "Renal ischemia modified by an angiotensin antagonist.", "content": "Renal ischemia modified by an angiotensin antagonist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361088"}
{"pmid": "4361089", "title": "A comparison of the hormone responsiveness of the prostate and seminal vesicles.", "content": "A comparison of the hormone responsiveness of the prostate and seminal vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361089"}
{"pmid": "4361092", "title": "Congenital epulis--a case report.", "content": "Congenital epulis--a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361092"}
{"pmid": "4361091", "title": "A psychophysiological study of nightmares and night terrors. 3. Mental content and recall of stage 4 night terrors.", "content": "A psychophysiological study of nightmares and night terrors. 3. Mental content and recall of stage 4 night terrors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361091"}
{"pmid": "4361095", "title": "Massive gingival hyperplasia preceding dental eruption in I-cell disease.", "content": "Massive gingival hyperplasia preceding dental eruption in I-cell disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361095"}
{"pmid": "4361096", "title": "Anomalous flexor sublimis muscle with incipient carpal tunnel syndrome. Case report.", "content": "Anomalous flexor sublimis muscle with incipient carpal tunnel syndrome. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361096"}
{"pmid": "4361100", "title": "Metabolic differences between normal and neoplastic cells: effects of aminonucleoside on cytoplasmic messenger RNA.", "content": "Metabolic differences between normal and neoplastic cells: effects of aminonucleoside on cytoplasmic messenger RNA. Treatment of cultured normal human fibroblasts with an adenosine analog (aminonucleoside of puromycin) rapidly inhibits the appearance of cytoplasmic messenger RNA, identified by its polyadenylate sequence. Similar treatment of SV40-transformed fibroblasts does not lead to such an inhibition. Cordycepin. another analog of adenosine. inlhibits polyadenylate-containing cytoplasmic RNA in both types of cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361100"}
{"pmid": "4361099", "title": "Dexamethasone stimulation of murine mammary tumor virus expression: a tissue culture source of virus.", "content": "Dexamethasone stimulation of murine mammary tumor virus expression: a tissue culture source of virus. In mouse cell lines derived from mammary adenocarcinomnas, the synthetic steroid dexamnethasone stimulates production of murine mammary tumor virus. Viral RNA and antigens are increased as much as 20-fold, and culture fluid supernatants from steroid-treated cells contain type B particles with reverse transcriptase. These cells provide a possible tissue culture source of this virus and a model system for studying the mechanism of action of corticosteroids and the regulation of transcription of integrated viral DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361099"}
{"pmid": "4361104", "title": "Brain tumors presenting with psychiatric symptomatology. (A five-year survey).", "content": "Brain tumors presenting with psychiatric symptomatology. (A five-year survey).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361104"}
{"pmid": "4361103", "title": "Diarrhoea in intensively-reared lambs.", "content": "Diarrhoea in intensively-reared lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361103"}
{"pmid": "4361105", "title": "Ultrastructure of a mycoplasma-like avian conjunctivitis agent.", "content": "Ultrastructure of a mycoplasma-like avian conjunctivitis agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361105"}
{"pmid": "4361106", "title": "Properties of mitochondrial thymidine kinases of parental and enzyme-deficient HeLa cells.", "content": "Properties of mitochondrial thymidine kinases of parental and enzyme-deficient HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361106"}
{"pmid": "4361108", "title": "Specificity of sugar-phospholipid interactions.", "content": "Specificity of sugar-phospholipid interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361108"}
{"pmid": "4361107", "title": "Induction of microsomal aryl hydrocarbon (3,4-benzo(alpha)pyrene) hydroxylase and cytochrome P-450K in rat kidney cortex. I. Characteristics of the hydroxylase system.", "content": "Induction of microsomal aryl hydrocarbon (3,4-benzo(alpha)pyrene) hydroxylase and cytochrome P-450K in rat kidney cortex. I. Characteristics of the hydroxylase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361107"}
{"pmid": "4361109", "title": "Kinetic studies of a hepatoma alkaline phosphatase.", "content": "Kinetic studies of a hepatoma alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361109"}
{"pmid": "4361111", "title": "Electron spin resonance of myosin spin labeled at the S1 thiol groups during hydrolysis of adenosine triphosphate.", "content": "Electron spin resonance of myosin spin labeled at the S1 thiol groups during hydrolysis of adenosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361111"}
{"pmid": "4361110", "title": "H2O2 production and cytochrome c peroxidase activity in mitochondria isolated from the trypanosomatid hemoflagellate Crithidia fasciculata.", "content": "H2O2 production and cytochrome c peroxidase activity in mitochondria isolated from the trypanosomatid hemoflagellate Crithidia fasciculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361110"}
{"pmid": "4361113", "title": "Effect of interferon on tumor forming ability of Walker carcinosarcoma 256 cells and secretion of exo-toxin by the bacillus, Clostridium welchii (type C).", "content": "Effect of interferon on tumor forming ability of Walker carcinosarcoma 256 cells and secretion of exo-toxin by the bacillus, Clostridium welchii (type C).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361113"}
{"pmid": "4361114", "title": "Subtilopeptidase a cleavage in the cyclic region of the peptide antibiotic polymyxin B1.", "content": "Subtilopeptidase a cleavage in the cyclic region of the peptide antibiotic polymyxin B1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361114"}
{"pmid": "4361115", "title": "Letter: Rapid relaxation of spin equilibrium in ferric myoglobin hydroxide.", "content": "Letter: Rapid relaxation of spin equilibrium in ferric myoglobin hydroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361115"}
{"pmid": "4361116", "title": "The chemistry of penicillanic acids. II. Some reactions of methyl penicillanate and its 6alpha-bromo- and 6,6-dibromo-derivatives.", "content": "The chemistry of penicillanic acids. II. Some reactions of methyl penicillanate and its 6alpha-bromo- and 6,6-dibromo-derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361116"}
{"pmid": "4361117", "title": "High-speed liquid chromatographic separation of equine estrogens.", "content": "High-speed liquid chromatographic separation of equine estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361117"}
{"pmid": "4361118", "title": "Evaluation of centrifugal chromatography. I. Seperation of steroid hormones on silca gel.", "content": "Evaluation of centrifugal chromatography. I. Seperation of steroid hormones on silca gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361118"}
{"pmid": "4361119", "title": "Radiologic seminar. CXXXVI. Linitis plastica: \"leather-bottle stomach\".", "content": "Radiologic seminar. CXXXVI. Linitis plastica: \"leather-bottle stomach\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361119"}
{"pmid": "4361122", "title": "Pancreatic insulin in diabetes mellitus.", "content": "Pancreatic insulin in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361122"}
{"pmid": "4361121", "title": "Chronic disease of liver and lungs in New Guinea.", "content": "Chronic disease of liver and lungs in New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361121"}
{"pmid": "4361120", "title": "Blood-pressure regulation in renal failure.", "content": "Blood-pressure regulation in renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361120"}
{"pmid": "4361124", "title": "Steroid biosynthesis by transplantable gonadal tumors of rat.", "content": "Steroid biosynthesis by transplantable gonadal tumors of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361124"}
{"pmid": "4361125", "title": "Receptors for androgens in rat epididymis. Interactions with 5alpha-androstane-3alpha,17beta-diol.", "content": "Receptors for androgens in rat epididymis. Interactions with 5alpha-androstane-3alpha,17beta-diol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361125"}
{"pmid": "4361123", "title": "Immunosuppressant agents in the treatment of glomerulonephritis. 1. Corticosteroid drugs.", "content": "Immunosuppressant agents in the treatment of glomerulonephritis. 1. Corticosteroid drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361123"}
{"pmid": "4361126", "title": "Effect of adenosine-3',5'-cyclic monophosphate on beta-hydroxy steroid dehydrogenase in the bovine corpus luteum.", "content": "Effect of adenosine-3',5'-cyclic monophosphate on beta-hydroxy steroid dehydrogenase in the bovine corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361126"}
{"pmid": "4361127", "title": "Serologic evidence of arbovirus activity in a moose population in Alberta.", "content": "Serologic evidence of arbovirus activity in a moose population in Alberta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361127"}
{"pmid": "4361128", "title": "Inclusion body hepatitis in a prairie falcon.", "content": "Inclusion body hepatitis in a prairie falcon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361128"}
{"pmid": "4361129", "title": "Survey for antibody to infectious bovine rhinotracheitis (IBR), bovine virus diarrhea (BVD) and parainfluenza 3 (PI3) in moose sera.", "content": "Survey for antibody to infectious bovine rhinotracheitis (IBR), bovine virus diarrhea (BVD) and parainfluenza 3 (PI3) in moose sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361129"}
{"pmid": "4361130", "title": "Infectious pancreatic necrosis virus--temperature and age factors in mortality.", "content": "Infectious pancreatic necrosis virus--temperature and age factors in mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361130"}
{"pmid": "4361131", "title": "The immune response of channel catfish. I. Basic responsiveness to soluble and viral antigens.", "content": "The immune response of channel catfish. I. Basic responsiveness to soluble and viral antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361131"}
{"pmid": "4361132", "title": "Pseudogout syndrome in hospital patients.", "content": "Pseudogout syndrome in hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361132"}
{"pmid": "4361133", "title": "Barium enema septicemia. Occurrence in a patient with leukemia.", "content": "Barium enema septicemia. Occurrence in a patient with leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361133"}
{"pmid": "4361134", "title": "Photoinactivation of Herpes simplex virus continues to look promising.", "content": "Photoinactivation of Herpes simplex virus continues to look promising.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361134"}
{"pmid": "4361135", "title": "On the phospholipids of Culex pipiens fatigans.", "content": "On the phospholipids of Culex pipiens fatigans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361135"}
{"pmid": "4361136", "title": "Lipid composition and endogenous respiration of pig heart mitochondria.", "content": "Lipid composition and endogenous respiration of pig heart mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361136"}
{"pmid": "4361137", "title": "Postnatal changes in the phospholipid composition of livers from young lambs.", "content": "Postnatal changes in the phospholipid composition of livers from young lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361137"}
{"pmid": "4361139", "title": "Determination of the position of ethylenic linkages in lipids.", "content": "Determination of the position of ethylenic linkages in lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361139"}
{"pmid": "4361138", "title": "Isomerization of L-glyceraldehyde to dihydroxyacetone during glyceride synthesis by rat liver microsomes.", "content": "Isomerization of L-glyceraldehyde to dihydroxyacetone during glyceride synthesis by rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361138"}
{"pmid": "4361140", "title": "Inhibition of phospholipase C by isosteric phosphinic acid analogues of lecithin.", "content": "Inhibition of phospholipase C by isosteric phosphinic acid analogues of lecithin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361140"}
{"pmid": "4361142", "title": "Genetic duplications induced at very high frequency by ultraviolet irradiation in Escherichia coli.", "content": "Genetic duplications induced at very high frequency by ultraviolet irradiation in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361142"}
{"pmid": "4361146", "title": "Management of spina bifida cystica. II. Initial management of the treated child.", "content": "Management of spina bifida cystica. II. Initial management of the treated child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361146"}
{"pmid": "4361144", "title": "The effects of l,l-dimethyl-4-phenyl-piperazinium (DMPP) in the cat superior cervical ganglion in situ.", "content": "The effects of l,l-dimethyl-4-phenyl-piperazinium (DMPP) in the cat superior cervical ganglion in situ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361144"}
{"pmid": "4361143", "title": "Mutants of Salmonella typhimurium deficient in DNA polymerase. I. Detection by their failure to produce colicin E1.", "content": "Mutants of Salmonella typhimurium deficient in DNA polymerase. I. Detection by their failure to produce colicin E1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361143"}
{"pmid": "4361147", "title": "Management of spina bifida cystica. III. Follow-up care and further treatment.", "content": "Management of spina bifida cystica. III. Follow-up care and further treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361147"}
{"pmid": "4361148", "title": "Somatomedin and growth after renal transplantation.", "content": "Somatomedin and growth after renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361148"}
{"pmid": "4361150", "title": "Neuronal circuitry in the nucleus lateralis of the cerebellum.", "content": "Neuronal circuitry in the nucleus lateralis of the cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361150"}
{"pmid": "4361141", "title": "Quantitative determination of urinary metabolites of cortisol in eluates from thin-layer chromatograms obtained by the partition method.", "content": "Quantitative determination of urinary metabolites of cortisol in eluates from thin-layer chromatograms obtained by the partition method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361141"}
{"pmid": "4361154", "title": "Hydroxamic acids of natural origin.", "content": "Hydroxamic acids of natural origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361154"}
{"pmid": "4361155", "title": "The biosynthesis of pteridines.", "content": "The biosynthesis of pteridines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361155"}
{"pmid": "4361157", "title": "Clostridium perfringens septicemia complicating degenerating uterine leiomyomas.", "content": "Clostridium perfringens septicemia complicating degenerating uterine leiomyomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361157"}
{"pmid": "4361158", "title": "Effect of prolonged continuous intracarotid arterial perfusion of hydroxyurea on the normal monkey brain.", "content": "Effect of prolonged continuous intracarotid arterial perfusion of hydroxyurea on the normal monkey brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361158"}
{"pmid": "4361156", "title": "The effects of long-term estrogen on hysterectomized women.", "content": "The effects of long-term estrogen on hysterectomized women. Presented is a report of 737 women subjected to hysterectomy and subsequently given estrogen therapy with conjugated equine estrogens.  A total of 9899 patient-years were studied.  The original objective of the study was to evaluate the role of estrogen in the development of carcinoma of the breast.  No statistical increase in breast cancer was observed.  The most striking finding was the unexpectedly low incidence of all cancer and the markedly low mortality rate.  A study was carried out on the subjective response of 550 of the women.  Questions were asked on general health, emotional status, and sex.  477 of the women said their health was better, 338 said that their nerves were better, and 181 out of 373 (61 were unmarried) said that sex was better.  It believed that due to the use of estrogen, delays were effected in the onset of osteoporosis, and these resulted in an improvement of the incidence of the skeletal fractures which might be anticipated in this age group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361156"}
{"pmid": "4361159", "title": "Studies on control of infections at time of intraocular surgery.", "content": "Studies on control of infections at time of intraocular surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361159"}
{"pmid": "4361161", "title": "Enzymatic theory of corneal ulceration---a beginning.", "content": "Enzymatic theory of corneal ulceration---a beginning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361161"}
{"pmid": "4361160", "title": "Bacterial flora of the lids and conjunctiva before, during, and after intraocular surgery.", "content": "Bacterial flora of the lids and conjunctiva before, during, and after intraocular surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361160"}
{"pmid": "4361163", "title": "Proceedings: How vital is mammography in the diagnosis and management of breast carcinoma?", "content": "Proceedings: How vital is mammography in the diagnosis and management of breast carcinoma?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361163"}
{"pmid": "4361165", "title": "Effects of REM deprivation and awakening on instrumental performance during stage 2 and REM sleep.", "content": "Effects of REM deprivation and awakening on instrumental performance during stage 2 and REM sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361165"}
{"pmid": "4361162", "title": "Separation of phosphoribulokinase from enzymes of the Calvin cycle in Hydrogenomonas eutropha H 16.", "content": "Separation of phosphoribulokinase from enzymes of the Calvin cycle in Hydrogenomonas eutropha H 16.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361162"}
{"pmid": "4361166", "title": "Hypnotizability predicted by digital computer-analyzed EEG pattern.", "content": "Hypnotizability predicted by digital computer-analyzed EEG pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361166"}
{"pmid": "4361168", "title": "Techniques of human breast neoplasm cell culture.", "content": "Techniques of human breast neoplasm cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361168"}
{"pmid": "4361170", "title": "Inhibition and enhancement of mammary tumorigenesis by 7,12-dimethylbenz (a) anthracene in the female sprague-dawley rat.", "content": "Inhibition and enhancement of mammary tumorigenesis by 7,12-dimethylbenz (a) anthracene in the female sprague-dawley rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361170"}
{"pmid": "4361171", "title": "A chromatographic comparison of the constituents of nutmeg and mace (Myristica fragrans Houtt.) with those of marihuana and hashish (Cannabis sativa L.).", "content": "A chromatographic comparison of the constituents of nutmeg and mace (Myristica fragrans Houtt.) with those of marihuana and hashish (Cannabis sativa L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361171"}
{"pmid": "4361172", "title": "Two-dimensional TLC of lipophilic compounds. Characterization of a mixed stationary phase permitting both adsorption TLC and reversed-partition TLC on one plate.", "content": "Two-dimensional TLC of lipophilic compounds. Characterization of a mixed stationary phase permitting both adsorption TLC and reversed-partition TLC on one plate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361172"}
{"pmid": "4361169", "title": "The carbohydrate moiety of rhodopsin: lectin-binding, chemical modification and fluorescence studies.", "content": "The carbohydrate moiety of rhodopsin: lectin-binding, chemical modification and fluorescence studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361169"}
{"pmid": "4361173", "title": "Gas-liquid chromatographic separation of equine estrogens.", "content": "Gas-liquid chromatographic separation of equine estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361173"}
{"pmid": "4361174", "title": "Evidence for dual corticosteroid-receptor mechanisms in the feedback control of adrenocorticotrophin secretion.", "content": "Evidence for dual corticosteroid-receptor mechanisms in the feedback control of adrenocorticotrophin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361174"}
{"pmid": "4361175", "title": "Editorial: Do human tumors show a chromosome pattern specific for each etiologic agent?", "content": "Editorial: Do human tumors show a chromosome pattern specific for each etiologic agent?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361175"}
{"pmid": "4361177", "title": "Heterogeneity of virus production and antigenicity detected in cell clones derived from a \"nonproducer\" neoplasm induced by Moloney murine sarcoma virus.", "content": "Heterogeneity of virus production and antigenicity detected in cell clones derived from a \"nonproducer\" neoplasm induced by Moloney murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361177"}
{"pmid": "4361176", "title": "Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.", "content": "Neoplasms and amyloidosis in strains of mice treated with 3-methylcholanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361176"}
{"pmid": "4361178", "title": "Rescue of cell-transforming virus from a non-virus-producing bovine cell culture transformed by feline sarcoma virus.", "content": "Rescue of cell-transforming virus from a non-virus-producing bovine cell culture transformed by feline sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361178"}
{"pmid": "4361179", "title": "Mammalian sarcoma-leukemia viruses. I. Infection of feline, bovine, and human cell cultures with Snyder-Theilen feline sarcoma virus.", "content": "Mammalian sarcoma-leukemia viruses. I. Infection of feline, bovine, and human cell cultures with Snyder-Theilen feline sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361179"}
{"pmid": "4361181", "title": "Immunoglobulin analysis of C57BL mice infected with a radiation-induced leukemia virus.", "content": "Immunoglobulin analysis of C57BL mice infected with a radiation-induced leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361181"}
{"pmid": "4361180", "title": "Replicating type-C virus particles in monolayer cell cultures of tissues from cattle with lymphosarcoma.", "content": "Replicating type-C virus particles in monolayer cell cultures of tissues from cattle with lymphosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361180"}
{"pmid": "4361182", "title": "Virus particles in primordial germ cells of fetal guinea pigs.", "content": "Virus particles in primordial germ cells of fetal guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361182"}
{"pmid": "4361183", "title": "Different chromosome morphology of diploid and aneuploid malignant cells.", "content": "Different chromosome morphology of diploid and aneuploid malignant cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361183"}
{"pmid": "4361184", "title": "In vitro effects of melanocyte-stimulating hormone, adrenocorticotropic hormone, 17 beta-estradiol, or testosterone propionate on Cloudman S91 mouse melanoma cells.", "content": "In vitro effects of melanocyte-stimulating hormone, adrenocorticotropic hormone, 17 beta-estradiol, or testosterone propionate on Cloudman S91 mouse melanoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361184"}
{"pmid": "4361185", "title": "Effect of feline leukemia virus on transferrred hamster fetuses.", "content": "Effect of feline leukemia virus on transferrred hamster fetuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361185"}
{"pmid": "4361187", "title": "Mixed Müllerian tumour of the corpus uteri.", "content": "Mixed Müllerian tumour of the corpus uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361187"}
{"pmid": "4361188", "title": "Clinicopathologic conference. Cholecystitis, pericholecystic abscess, and septicemia due to Clostridium perfringens. Case presentation.", "content": "Clinicopathologic conference. Cholecystitis, pericholecystic abscess, and septicemia due to Clostridium perfringens. Case presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361188"}
{"pmid": "4361189", "title": "Letter: Nephroblastoma.", "content": "Letter: Nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361189"}
{"pmid": "4361192", "title": "A diallel analysis of the genetic underpinnings of mouse sleep.", "content": "A diallel analysis of the genetic underpinnings of mouse sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361192"}
{"pmid": "4361195", "title": "Hepatic scintiangiographic patterns.", "content": "Hepatic scintiangiographic patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361195"}
{"pmid": "4361194", "title": "Absence of ponto-geniculo-occipital (PGO) spikes in rats.", "content": "Absence of ponto-geniculo-occipital (PGO) spikes in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361194"}
{"pmid": "4361196", "title": "Angiographic features of focal lymphoma of the liver.", "content": "Angiographic features of focal lymphoma of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361196"}
{"pmid": "4361199", "title": "Comparative study of the incorporation of 32P into the phospholipids of membranes from Novikoff hepatoma ascites cells and liver cells from normal and tumor bearing animals.", "content": "Comparative study of the incorporation of 32P into the phospholipids of membranes from Novikoff hepatoma ascites cells and liver cells from normal and tumor bearing animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361199"}
{"pmid": "4361193", "title": "The water tank technique: avoidance conditioning as a function of water level and pedestal size.", "content": "The water tank technique: avoidance conditioning as a function of water level and pedestal size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361193"}
{"pmid": "4361201", "title": "Diabetes and hypertensive vascular disease. Mechanisms and treatment.", "content": "Diabetes and hypertensive vascular disease. Mechanisms and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361201"}
{"pmid": "4361186", "title": "Control of the enzyme systems in plasma renin activity measurement by angiotensin I radioimmunoassay.", "content": "Control of the enzyme systems in plasma renin activity measurement by angiotensin I radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361186"}
{"pmid": "4361203", "title": "Radiopertechnetate flow study and liver scan in a case of benign hepatoma (liver cell adenoma).", "content": "Radiopertechnetate flow study and liver scan in a case of benign hepatoma (liver cell adenoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361203"}
{"pmid": "4361211", "title": "Wilm's-aniridia syndrome with transient hypo-gamma-globulinaemia of infancy.", "content": "Wilm's-aniridia syndrome with transient hypo-gamma-globulinaemia of infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361211"}
{"pmid": "4361213", "title": "Lymphangiography in patients with pulmonary dysfunction.", "content": "Lymphangiography in patients with pulmonary dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361213"}
{"pmid": "4361212", "title": "The pituitary and primary hypothyroidism. Enlargement and unusual growth hormone secretory responses.", "content": "The pituitary and primary hypothyroidism. Enlargement and unusual growth hormone secretory responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361212"}
{"pmid": "4361214", "title": "Thyrotoxicosis from molar thyrotropin.", "content": "Thyrotoxicosis from molar thyrotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361214"}
{"pmid": "4361202", "title": "The REM state and drugs.", "content": "The REM state and drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361202"}
{"pmid": "4361216", "title": "The binding of acetylcholine to receptors and its removal from the synaptic cleft.", "content": "The binding of acetylcholine to receptors and its removal from the synaptic cleft. 1. Acetylcholine (ACh) noise and miniature end-plate potentials were recorded with focal external micro-electrodes.2. The effect of prostigmine on the time course of the ;molecular' and ;quantal' transmitter actions was studied. Prostigmine (10(-6) g/ml.) has little or no effect on the duration of the molecular ;gating action', while it greatly prolongs the quantal conductance change.3. After inhibition of ACh hydrolysis, the removal of the transmitter from the synapse is generally too slow to be accounted for by free diffusion. It is suggested that diffusion is delayed by binding to post-synaptic receptors. This is consistent with the finding that receptor blockage by curare or alpha-bungarotoxin shortens as well as reduces quantal transmitter action.4. The correlated effects of the receptor-blocking agents, on size and time course of the miniature end-plate currents, were subjected to a simple analysis. Its result suggests that after inhibition of cholinesterase about two thrids of the quantal packet of ACh combines with post-synaptic receptors.5. During focal external recording the effect of prostigmine on the time course of miniature end-plate potentials can become exaggerated due to what appears to be a compression artifact which obstructs outward diffusion of the transmitter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361216"}
{"pmid": "4361215", "title": "Membrane properties and inhibitory innervation of the circular muscle cells of guinea-pig caecum.", "content": "Membrane properties and inhibitory innervation of the circular muscle cells of guinea-pig caecum. 1. The membrane properties of the circular muscle cells of guinea-pig caecum and nervous factors influencing the muscle activity were studied with micro-electrodes using partition and field stimulating methods.2. The mean membrane potential was -52 mV. Spontaneous discharges appeared as regular bursts between silent periods, as regular spikes without silent period, or as regular slow potential changes with superimposed spikes.3. Spontaneous spikes with overshoot were frequently observed. The mean maximum rate of rise was 5.2 V/sec. The mean conduction velocity of evoked spikes was 5.4 cm/sec.4. The amplitude of the elctrotonic potential was linearly proportional to the current applied by the partition stimulating method. The spatial decay of the electrotonic potential along the tissue was exponential, with a mean length constant of 1.7 mm.5. The time constants of the membrane calculated from the electrotonic potential, and from the conduction velocity, length constant and time course of the foot of the spike were about 200 and 100 msec respectively. These results indicate that the circular muscle of guinea-pig caecum possesses cable like properties.6. Field stimulation (0.3 msec pulse duration) to the circular muscle evoked three different responses successively, i.e. initial depolarization (initial excitatory junction potential) with or without spike, hyperpolarization (inhibitory junction potential) and delayed depolarization (delayed excitatory junction potential) with or without spikes.7. These three different potential changes were completely blocked by treatment with tetrodotoxin (5 x 10(-6) g/ml.), and both the initial and late excitatory junction potentials were blocked by treatment with atropine (5 x 10(-5) g/ml.).8. The distribution of inhibitory nerves in the circular muscle cells was investigated. The results indicate that inhibitory nerves arise from Auerbach's plexus situated just beneath the taenia coli and the nerve branches spread over the whole distance from one taenia coli to the next along the ciruclar muscle cells, a width of about 3 mm.9. The mean conduction velocity of excitation of the inhibitory nerves was 16.0 cm/sec. Hexamethonium, in a concentration of 5 x 10(-6) g/ml. depolarized the circular muscle membrane and lowered the rate of rise and fall of spike, but did not block the generation of inhibitory junction potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361215"}
{"pmid": "4361217", "title": "The role of the nurse in a drug crisis center.", "content": "The role of the nurse in a drug crisis center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361217"}
{"pmid": "4361219", "title": "The clinical specialist in the geographic unit system.", "content": "The clinical specialist in the geographic unit system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361219"}
{"pmid": "4361226", "title": "Corticosteroid therapy for rheumatoid arthritis.", "content": "Corticosteroid therapy for rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361226"}
{"pmid": "4361227", "title": "The use of glucocorticoids in intestinal disease.", "content": "The use of glucocorticoids in intestinal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361227"}
{"pmid": "4361229", "title": "The radiotherapy of nasopharyngeal angiofibroma.", "content": "The radiotherapy of nasopharyngeal angiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361229"}
{"pmid": "4361230", "title": "A computer model for the study of image formation of blood vessels smaller than the exposing focal spot.", "content": "A computer model for the study of image formation of blood vessels smaller than the exposing focal spot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361230"}
{"pmid": "4361221", "title": "One interdisciplinary planning team: a case study.", "content": "One interdisciplinary planning team: a case study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361221"}
{"pmid": "4361228", "title": "The use of antibodies to study cell structure and metabolism.", "content": "The use of antibodies to study cell structure and metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361228"}
{"pmid": "4361232", "title": "Giant fibro-adenoma (cystosarcoma phyllodes) in adolescent females--a clinicopathological study.", "content": "Giant fibro-adenoma (cystosarcoma phyllodes) in adolescent females--a clinicopathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361232"}
{"pmid": "4361220", "title": "Infantile autism: the puzzle.", "content": "Infantile autism: the puzzle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361220"}
{"pmid": "4361225", "title": "A follow-up survey of the post-treatment adaptation of former day hospital patients.", "content": "A follow-up survey of the post-treatment adaptation of former day hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361225"}
{"pmid": "4361234", "title": "Amoebic perforation of the intestine in children.", "content": "Amoebic perforation of the intestine in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361234"}
{"pmid": "4361218", "title": "The pros and cons of methadone maintenance.", "content": "The pros and cons of methadone maintenance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361218"}
{"pmid": "4361233", "title": "The reduction of surgical wound infections by topical cephaloridine: a controlled clinical trial.", "content": "The reduction of surgical wound infections by topical cephaloridine: a controlled clinical trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361233"}
{"pmid": "4361223", "title": "Black patient, white therapist.", "content": "Black patient, white therapist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361223"}
{"pmid": "4361224", "title": "Higher education in nursing.", "content": "Higher education in nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361224"}
{"pmid": "4361222", "title": "Korsakoff's syndrome.", "content": "Korsakoff's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361222"}
{"pmid": "4361236", "title": "Cancer of the biliary system: a study of 445 cases.", "content": "Cancer of the biliary system: a study of 445 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361236"}
{"pmid": "4361235", "title": "Multiple intestinal malignancies and prolonged survival in a young woman.", "content": "Multiple intestinal malignancies and prolonged survival in a young woman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361235"}
{"pmid": "4361237", "title": "Proceedings: Carcinoma of the urachus.", "content": "Proceedings: Carcinoma of the urachus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361237"}
{"pmid": "4361239", "title": "Retroperitoneal tumors in children.", "content": "Retroperitoneal tumors in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361239"}
{"pmid": "4361241", "title": "Letter: Potential hazards of HClO4 in heated systems where esters are involved.", "content": "Letter: Potential hazards of HClO4 in heated systems where esters are involved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361241"}
{"pmid": "4361240", "title": "Letter: Phosphodiesterase: an important role in cyclic nucleotide regulation in the retina.", "content": "Letter: Phosphodiesterase: an important role in cyclic nucleotide regulation in the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361240"}
{"pmid": "4361242", "title": "A depression of cell-mediated immunity to measles antigen in patients with systemic lupus erythematosus.", "content": "A depression of cell-mediated immunity to measles antigen in patients with systemic lupus erythematosus. Using the direct migration inhibition test, response to measles antigen in patients with systemic lupus erythematosus (SLE) was found to be decreased when compared with that of normal subjects. No alteration was observed in similar experiments using parainfluenza type 1 and rubella antigens. The specific decrease in measles antigen effect showed no obvious correlation with activity of SLE or with the presence of lymphocytotoxic antibodies. Whether the specificity of the decrease in reactivity is due to some particular relationship between the measles virus or antigen and SLE, or to the possibility that measles reactivity is a more sensitive indicator of a generalized defect of cell-mediated immunity, remains unclear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361242"}
{"pmid": "4361244", "title": "Interferon production of human leukemic cells--an in-vitro assay.", "content": "Interferon production of human leukemic cells--an in-vitro assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361244"}
{"pmid": "4361243", "title": "Interaction of cholera toxin and toxin derivatives with lymphocytes. I. Binding properties and interference with lectin-induced cellular stimulation.", "content": "Interaction of cholera toxin and toxin derivatives with lymphocytes. I. Binding properties and interference with lectin-induced cellular stimulation. The interaction of cholera toxin and a number of toxin derivatives, containing different proportions of light and heavy toxin-composing subunits (L and H), with mouse lymphocytes was studied. Experiments with [(125)I]toxin showed that a single cell can rapidly, within minutes, bind up to 40,000 molecules of toxin, the association constant was estimated to 7 +/- 4 x 10(8) liters/mol, and binding was found to be very similar at 37 degrees C and 5 degrees C. Immunofluorescence studies revealed that the toxin attachment is located on the cell surface, and that purified L subunit but not H subunit binds to the cells. A natural cholera toxoid, built up by aggregated L subunits, showed almost identical binding properties as toxin to the cells. Pure G(M1) ganglioside, the proposed membrane receptor structure for toxin, prevented entirely the cellular binding of both toxin and toxoid. Cholera toxin in concentrations down to approximately 5 x 10(-11) mol/liter (corresponding to 10 bound molecules/cell) inhibited thymus cells from being stimulated to DNA synthesis by concanavalin A (con A), and spleen cells from such stimulation by phytohemagglutinin. The G(M1) ganglioside but not a series of other pure structurally related gangliosides and neutral glycosphingolipids neutralized this toxin activity. Toxin derivatives which, in similarity with toxin, possessed H as well as L subunits but in other proportions, were potent inhibitors of con A-induced thymocyte stimulation, whereas the natural toxoid (aggregated L subunits), purified toxin L subunit and purified toxin H subunit were up to 300-fold less active on a weight basis. The capacity of cholera proteins to inhibit con A-induced thymocyte stimulation correlated well with their activity in the rabbit intradermal toxicity assay. The inhibitory action of cholera toxin on con A-induced thymocyte stimulation did not depend on decreased cell viability from the toxin treatment, nor was it caused by a reaction between toxin and con A. [(125)I]con A bound equally well to the cells when toxin was present as when it was absent, which proves that the toxin did not compete for cellular con A receptors. Nor did the toxin seem to disturb the general mobility of membrane receptors or their ability to accumulate in caps. It is concluded that the L type of subunit confers rapid and firm binding of cholera toxin to lymphocyte membranes, probably to G(M1) ganglioside receptors. For biologic activity the additional presence of H subunit is important. One manifestation of toxin action on lymphocytes is inhibition of lectin-induced DNA synthesis; probably this effect relates to the ability of cholera toxin to raise the levels of intracellular cyclic 3'5'-adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361243"}
{"pmid": "4361245", "title": "An apparently new enterovirus isolated from patients with disease of the central nervous system.", "content": "An apparently new enterovirus isolated from patients with disease of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361245"}
{"pmid": "4361246", "title": "Type B hepatitis antigen and antibody among prostitutes and nuns: a study of possible venereal transmission.", "content": "Type B hepatitis antigen and antibody among prostitutes and nuns: a study of possible venereal transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361246"}
{"pmid": "4361247", "title": "Microbiologic study of street heroin and injection paraphernalia.", "content": "Microbiologic study of street heroin and injection paraphernalia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361247"}
{"pmid": "4361248", "title": "Virucidal activity of H2O2-generating bacteria: requirement for peroxidase and a halide.", "content": "Virucidal activity of H2O2-generating bacteria: requirement for peroxidase and a halide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361248"}
{"pmid": "4361249", "title": "Pulmonary defense mechanisms in consolidated and nonconsolidated regions of lungs infected with Sendai virus.", "content": "Pulmonary defense mechanisms in consolidated and nonconsolidated regions of lungs infected with Sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361249"}
{"pmid": "4361251", "title": "Subcellular distribution of cardiac glycosides in rabbit and rat myometrium and their binding to isolated plasma membrane.", "content": "Subcellular distribution of cardiac glycosides in rabbit and rat myometrium and their binding to isolated plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361251"}
{"pmid": "4361250", "title": "Chemical studies of potential relevance to penicillin hypersensitivity: kinetic studies of methicillin, phenoxymethylpenicillin and their penicillenic acids.", "content": "Chemical studies of potential relevance to penicillin hypersensitivity: kinetic studies of methicillin, phenoxymethylpenicillin and their penicillenic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361250"}
{"pmid": "4361253", "title": "The ultrastructure and function of the tentacle in Rhyncheta cyclopum Zenker (Ciliatea, Suctorida).", "content": "The ultrastructure and function of the tentacle in Rhyncheta cyclopum Zenker (Ciliatea, Suctorida).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361253"}
{"pmid": "4361252", "title": "Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.", "content": "Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361252"}
{"pmid": "4361257", "title": "Mutagenic properties of DNA- and RNA-containing viruses nonvirulent for Drosophilia.", "content": "Mutagenic properties of DNA- and RNA-containing viruses nonvirulent for Drosophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361257"}
{"pmid": "4361258", "title": "Study of the properties of a DNA-polymerase-deficient mutant of Escherichia coli.", "content": "Study of the properties of a DNA-polymerase-deficient mutant of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361258"}
{"pmid": "4361262", "title": "Pharmacological fibrinolysis.", "content": "Pharmacological fibrinolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361262"}
{"pmid": "4361263", "title": "Inhibition of platelet aggregation by isochinoline derivatives.", "content": "Inhibition of platelet aggregation by isochinoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361263"}
{"pmid": "4361264", "title": "The mechanism of intragenic recombination.", "content": "The mechanism of intragenic recombination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361264"}
{"pmid": "4361265", "title": "Paramutation.", "content": "Paramutation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361265"}
{"pmid": "4361266", "title": "Genetics of resistance to environmental stresses in Drosophila populations.", "content": "Genetics of resistance to environmental stresses in Drosophila populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361266"}
{"pmid": "4361267", "title": "Pharmacological actions of a novel O-acetylsalicylic acid composition.", "content": "Pharmacological actions of a novel O-acetylsalicylic acid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361267"}
{"pmid": "4361269", "title": "Insulin interactions with its receptors: experimental evidence for negative cooperativity.", "content": "Insulin interactions with its receptors: experimental evidence for negative cooperativity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361269"}
{"pmid": "4361270", "title": "Cyclic AMP binding to living cells of Dictyostelium discoideum in presence of excess cyclic GMP.", "content": "Cyclic AMP binding to living cells of Dictyostelium discoideum in presence of excess cyclic GMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361270"}
{"pmid": "4361268", "title": "[Prolactin cell tumors in animal experiments and in man].", "content": "[Prolactin cell tumors in animal experiments and in man].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361268"}
{"pmid": "4361271", "title": "Determination of oxidation and spin states of heme iron. Resonance Raman spectroscopy of cytochrome c, microperoxidase, and horseradish peroxidase.", "content": "Determination of oxidation and spin states of heme iron. Resonance Raman spectroscopy of cytochrome c, microperoxidase, and horseradish peroxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361271"}
{"pmid": "4361273", "title": "Effect of potassium cyanate on the catalytic activities of carbamyl phosphate synthetase.", "content": "Effect of potassium cyanate on the catalytic activities of carbamyl phosphate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361273"}
{"pmid": "4361272", "title": "A new procedure for the reconstitution of biologically active phospholipid vesicles.", "content": "A new procedure for the reconstitution of biologically active phospholipid vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361272"}
{"pmid": "4361279", "title": "Detection of antigens determined by the Epstein Barr virus (EBV) in human lymphoblastoid cell culture lines by elution of specific radioiodine labeled antibody.", "content": "Detection of antigens determined by the Epstein Barr virus (EBV) in human lymphoblastoid cell culture lines by elution of specific radioiodine labeled antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361279"}
{"pmid": "4361278", "title": "Neutrophilic leukocytes in immunologic reactions in vitro. 3. Pharmacologic modulation of lysosomal constituent release.", "content": "Neutrophilic leukocytes in immunologic reactions in vitro. 3. Pharmacologic modulation of lysosomal constituent release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361278"}
{"pmid": "4361280", "title": "Mammalian collagenases.", "content": "Mammalian collagenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361280"}
{"pmid": "4361281", "title": "Lipid lowering drugs and hyperlipidaemia.", "content": "Lipid lowering drugs and hyperlipidaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361281"}
{"pmid": "4361283", "title": "The sequential inactivation of glycogen phosphorylase and activation of glycogen synthetase in liver after the administration of glucose to mice and rats. The mechanism of the hepatic threshold to glucose.", "content": "The sequential inactivation of glycogen phosphorylase and activation of glycogen synthetase in liver after the administration of glucose to mice and rats. The mechanism of the hepatic threshold to glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361283"}
{"pmid": "4361284", "title": "Pulse-recovery studies on cycloheximide-insensitive protein synthesis in Neurospora. Association of products with cytochrome-oxidase.", "content": "Pulse-recovery studies on cycloheximide-insensitive protein synthesis in Neurospora. Association of products with cytochrome-oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361284"}
{"pmid": "4361285", "title": "A comparison of mitochondrially synthesized proteins from whole mitochondria and cytochrome oxidase in Neurospora.", "content": "A comparison of mitochondrially synthesized proteins from whole mitochondria and cytochrome oxidase in Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361285"}
{"pmid": "4361286", "title": "Measurements of the concentration of active sites in preparations of yeast alcohol dehydrogenase.", "content": "Measurements of the concentration of active sites in preparations of yeast alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361286"}
{"pmid": "4361288", "title": "A simplified procedure for the assay of adenosine 3':5'-monophosphate by the activation of liver phosphorylase.", "content": "A simplified procedure for the assay of adenosine 3':5'-monophosphate by the activation of liver phosphorylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361288"}
{"pmid": "4361287", "title": "The effect of adenosine analogues on the ATP-pyrophosphate exchange reaction catalysed by methionyl-tRNA synthetase.", "content": "The effect of adenosine analogues on the ATP-pyrophosphate exchange reaction catalysed by methionyl-tRNA synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361287"}
{"pmid": "4361290", "title": "Study of some glycolytic enzymes of mouse fibrosarcoma.", "content": "Study of some glycolytic enzymes of mouse fibrosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361290"}
{"pmid": "4361294", "title": "Collagenolytic activity of dental plaque associated with periodontal pathology.", "content": "Collagenolytic activity of dental plaque associated with periodontal pathology. Certain dental plaques, removed from sites of gingival and periodontal pathology in mentally retarded, institutionalized individuals, when incubated in phosphate buffer with Achilles tendon collagen, gave rise to an increase in ninhydrin-positive material. These plaques, while showing great variability, released significantly more ninhydrin-positive material per milligram of plaque (wet weight) than did either the endogenous or heat-treated controls. Certain plaques could also break down soluble, tritiated, labeled collagen isolated from the calvaria of chicken embryos. Bacteroides melaninogenicus and Clostridia histolyticum were found in plaques by either fluorescent antibody or cultural methods. C. histolyticum, when detected, accounted for about 0.01 to 0.1% of the bacteria in plaque. A conspicuous isolate from some plaques was a Bacillus species which rapidly liquefied gelatin. Cell-free supernatants of this organism were able to degrade about 50 to 70% of the soluble collagen when incubated at 36 C. C. histolyticum ATCC 8034 caused an 80% degradation of the collagen under the same conditions of incubation. The Bacillus strains were facultative, could ferment glucose, reduced nitrate to nitrite, and were catalase, indole, and urease negative. The limited taxonomic information for the isolates is compatible with the description given for Bacillus cereus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361294"}
{"pmid": "4361295", "title": "Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils.", "content": "Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils. Human polymorphonuclear neutrophils (PMN) were made anaerobic by nitrogen washout (oxygen saturation <1%, Eh < -42 mV at pH 7.0), and the ability of the cells to kill bacteria was assayed and compared to the bactericidal activity of aerobic PMN. Anaerobic PMN were able to kill Staphylococcus epidermidis, Enterococcus, viridans streptococci, Pseudomonas aeruginosa, Peptostreptococcus anaerobius, Bacteroides fragilis, Clostridium perfringens, and Peptococcus magnus normally. Organisms that were not killed normally by anaerobic PMN included Staphylococcus aureus (strains Wood 46 and 502a), Escherichia coli, Serratia marcescens, Klebsiella pneumoniae, Proteus vulgaris, and Salmonella typhimurium. These findings suggest that mechanisms other than those dependent on hydrogen peroxide may be important in the killing of some bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361295"}
{"pmid": "4361296", "title": "Replication or inactivation of different viruses by human lymphocyte preparations.", "content": "Replication or inactivation of different viruses by human lymphocyte preparations. Cultures of phytohemagglutinin-stimulated, unstimulated, and frozen and thawed mononuclear (as controls) cells from normal human donors were infected with different viruses. A variable pattern of virus infectivity was noted, and influenza and Coxsackie virus were rapidly inactivated even by stimulated lymphocytes. Direct inactivation by lymphocytes may be one form of host defense in infection by some viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361296"}
{"pmid": "4361293", "title": "Capsular polysaccharide of Clostridium perfringens Hobbs 10.", "content": "Capsular polysaccharide of Clostridium perfringens Hobbs 10. A capsular polysaccharide was isolated from a strain of Clostridium perfringens Hobbs 10 type A by cold-water extraction of whole, heavily encapsulated cells. The water-soluble polymer was isolated by alcohol precipitation and purified by treatment with chloroform-butanol, cetytrimethylammonium bromide, and column gel permeation chromatography by using Bio-Gel A-5m agarose. The formation of a single precipitin line, when the isolated polysaccharide was reacted with its homologous antisera by double diffusion in gel, was considered a criterion of immunochemical purity. The purified polymer appeared as a single peak when eluted from diethylaminoethyl-Sephadex with a linear gradient of NaCl. The polysaccharide was composed of glucose, galactose, galactosamine, and iduronic acid in a molar ratio of 4.1:5.1.7:1, respectively. These constituents accounted for 83% of the dry weight. The polysaccharide appeared to have a molecular weight of 40,000 and exhibited aggregation up to 120,000. A trace of peptide material could not be removed during purification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361293"}
{"pmid": "4361291", "title": "Epidemiological and biochemical studies on thiamine-less dwarf-colony variants of Staphylococcus aureus as etiological agents of bovine mastitis.", "content": "Epidemiological and biochemical studies on thiamine-less dwarf-colony variants of Staphylococcus aureus as etiological agents of bovine mastitis. Dwarf-colony (D) variants of Staphylococcus aureus are relatively widespread etiological agents of bovine mastitis in Israel. D strains grow on ordinary solid nutrient media with pinpoint, transparent colonies. An epidemiological study indicated that these variants are more communicable than normal (N) S. aureus strains. Biochemically, several types of metabolic defects have been demonstrated among the D strains: strains from one herd were pantothenate-less, most of the other isolates were thiamine-less, and a few of them were both thiamine-and pantothenate-less. Among the thiamineauxotrophs were a few (from one herd) which were unable to concentrate thiamine-thiazole, whereas all of the other strains required thiamine-pyrimidine (HMP) in the form of pyrophosphate (HMP-PP). At least some of these D strains were defective in three functions: concentrative uptake of HMP, phosphorylation of HMP, and phosphorylation of HMP-monophosphate. Since mutants with normal growth occurred readily, we assumed that the information for these three functions exists on a polycistronic operon. Quantitative requirements for HMP-PP varied highly among the D strains, and other data also indicated that HMP-PP-requiring strains had not developed from a common source.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361291"}
{"pmid": "4361292", "title": "Lipid catabolism of relapsing fever borreliae.", "content": "Lipid catabolism of relapsing fever borreliae. Relapsing fever borreliae require lipid compounds for growth in vitro. In this study, the major pathways of lipid catabolism in three species of tick-borne relapsing fever borreliae were investigated. Thin-layer chromatography was used to compare chloroform-methanol extracts of fresh culture media with extracts of exhausted culture media after organisms were removed by centrifugation. The chromatographic data demonstrated that lysolecithin was removed from the culture media during growth of the spirochetes, whereas lecithin, sphingomyelin, triglycerides, and cholesterol esters were not affected by growth of the organisms. Sonic extracts of the organism were tested for the presence of specific enzymes of lipid catabolism. Lysolecithinase, glycerophosphorylcholine diesterase, and acid phosphatase activities were demonstrated. Thus, these organisms can sequentially dissimilate lysolecithin to fatty acids, choline, inorganic phosphate, and glycerol. Assays for phospholipases A, C, and D, alpha-glycerophosphate dehydrogenase, alkaline phosphatase, and lipase were negative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361292"}
{"pmid": "4361297", "title": "Combined effects of phytohemagglutinin and staphylococcal enterotoxin B on deoxyribonucleic acid synthesis during blast transformation in human lymphocytes.", "content": "Combined effects of phytohemagglutinin and staphylococcal enterotoxin B on deoxyribonucleic acid synthesis during blast transformation in human lymphocytes. Three mitogenic agents, phytohemagglutinin (PHA), staphylococcal enterotoxin B (SEB), and concanavalin A (Con A) were tested for their effects on deoxyribonucleic acid (DNA) synthesis in the normal human lymphocyte. When optimal concentrations of PHA and SEB were combined, tritiated thymidine incorporation in lymphocytes derived from several donors was enhanced significantly. In the presence of graded concentrations of one of these mitogens added to fixed optimal concentrations of the other, this enhancement was shown to be additive. By contrast, when PHA or SEB were combined with Con A, the resulting thymidine incorporation was slightly lower than for either mitogen alone. An inhibition of further thymidine incorporation when puromycin was added to lymphocytes incubated with PHA and SEB suggested that the additive effect of these mitogens was due to increased enzyme synthesis. To define potential differences in mechanisms of action underlying the additive effect of SEB and PHA, the relative contribution of the de novo and salvage pathways for pyrimidine biosynthesis was tested with cytidine, a specific salvage pathway inhibitor. Cytidine (10(-3) M) inhibited synthesis through the salvage pathway, but did not significantly alter induction of carbamyl phosphate synthetase II, the rate-limiting enzyme for the de novo pathway. An inhibition of DNA synthesis by millimolar cytidine concentrations in lymphocytes incubated with PHA or SEB, singly or in combination, suggested that pyrimidines for the observed enhancement of DNA synthesis were derived largely via the salvage pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361297"}
{"pmid": "4361298", "title": "Antibody against Clostridium perfringens type A enterotoxin in human sera.", "content": "Antibody against Clostridium perfringens type A enterotoxin in human sera. Antibody against Clostridium perfringens type A enterotoxin was found in 82% of Brazilian and 65% of American serum samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361298"}
{"pmid": "4361301", "title": "Stereoelectronic properties of metalloenzymes. II. Effects of ligand coordination on the electron spin resonance spectrum of galactose oxidase as a probe of structure and function.", "content": "Stereoelectronic properties of metalloenzymes. II. Effects of ligand coordination on the electron spin resonance spectrum of galactose oxidase as a probe of structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361301"}
{"pmid": "4361300", "title": "Stereoelectronic properties of metalloenzymes. I. A comparison of the coordination of copper (II) in galactose oxidase and a model system, N,N'-ethylenebis(trifluoroacetylacetoniminato)copper(II).", "content": "Stereoelectronic properties of metalloenzymes. I. A comparison of the coordination of copper (II) in galactose oxidase and a model system, N,N'-ethylenebis(trifluoroacetylacetoniminato)copper(II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361300"}
{"pmid": "4361299", "title": "Reaction of phenylmethanesulfonyl-alpha-chymotrypsin with hydrogen peroxide and other nucleophiles.", "content": "Reaction of phenylmethanesulfonyl-alpha-chymotrypsin with hydrogen peroxide and other nucleophiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361299"}
{"pmid": "4361302", "title": "Cation radicals of tetraalkylporphyrins.", "content": "Cation radicals of tetraalkylporphyrins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361302"}
{"pmid": "4361303", "title": "Studies on the sarcoplasmic reticulum of rat, cat and sheep intrafusal fibres.", "content": "Studies on the sarcoplasmic reticulum of rat, cat and sheep intrafusal fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361303"}
{"pmid": "4361304", "title": "The ultrastructure of Leydig cells in the testis of the domestic fowl.", "content": "The ultrastructure of Leydig cells in the testis of the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361304"}
{"pmid": "4361306", "title": "Pressure accelerated chromatography through microparticulate silica columns packed by centrifugation.", "content": "Pressure accelerated chromatography through microparticulate silica columns packed by centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361306"}
{"pmid": "4361305", "title": "Report on microbiological methods.", "content": "Report on microbiological methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361305"}
{"pmid": "4361307", "title": "Tumorous hyperparathyroidism in hypophosphatemic vitamin D--resistant rickets.", "content": "Tumorous hyperparathyroidism in hypophosphatemic vitamin D--resistant rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361307"}
{"pmid": "4361308", "title": "Novel analogs of nucleoside 3',5'-cyclic phosphates. I. 5'-Mono- and dimethyl analogs of adenosine 3',5'-cyclic phosphate.", "content": "Novel analogs of nucleoside 3',5'-cyclic phosphates. I. 5'-Mono- and dimethyl analogs of adenosine 3',5'-cyclic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361308"}
{"pmid": "4361318", "title": "Phospholipids in biology and medicine (second of two parts).", "content": "Phospholipids in biology and medicine (second of two parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361318"}
{"pmid": "4361321", "title": "Eighteenth Bowditch lecture. Motor aspects of cerebellar control.", "content": "Eighteenth Bowditch lecture. Motor aspects of cerebellar control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361321"}
{"pmid": "4361323", "title": "Surgery of atherosclerosis below the inguinal ligament. The value of profundaplasty.", "content": "Surgery of atherosclerosis below the inguinal ligament. The value of profundaplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361323"}
{"pmid": "4361322", "title": "Role of viruses in the etiology of congenital malformations.", "content": "Role of viruses in the etiology of congenital malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361322"}
{"pmid": "4361324", "title": "Separation of prostaglandins A, B and C by thin-layer chromatography on ferric chloride impregnated silica gel.", "content": "Separation of prostaglandins A, B and C by thin-layer chromatography on ferric chloride impregnated silica gel. A convenient thin-layer chromatographic method for separating and isolating the isomeric prostaglandins A1, B1, and C1 under non-alkaline conditions was developed as a prerequisite for the in vivo investigation of the metabolism of PGA1.  The method was based on thin-layer chromatography on ferric chloride impregnanted silica gel.  The resolution of prostaglandin A from prostaglandin B proved to be superior to that on silica-gel thin-layer chromatography plates impregnated with silver nitrate.  Thin-layer chromatography has the advantages of simplicity, speed, and amenability to radioactivity scanning.  The method should find application in the separation of other prostaglandins, as well as a number of other classes of compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361324"}
{"pmid": "4361325", "title": "A review of myelography.", "content": "A review of myelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361325"}
{"pmid": "4361332", "title": "Food safety and food poisoning.", "content": "Food safety and food poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361332"}
{"pmid": "4361334", "title": "On the effects and the mechanism of action of corticosteroids in normal and neoplastic target tissues: findings and hypotheses, with a review of information on intracellular steroid receptors in general.", "content": "On the effects and the mechanism of action of corticosteroids in normal and neoplastic target tissues: findings and hypotheses, with a review of information on intracellular steroid receptors in general.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361334"}
{"pmid": "4361333", "title": "The metabolism of tamoxifen (I.C.I. 46,474). I. In laboratory animals.", "content": "The metabolism of tamoxifen (I.C.I. 46,474). I. In laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361333"}
{"pmid": "4361335", "title": "Effect of cyclic AMP and polyadenylic acid treatment on the delayed hypersensitivity of guinea pigs.", "content": "Effect of cyclic AMP and polyadenylic acid treatment on the delayed hypersensitivity of guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361335"}
{"pmid": "4361336", "title": "Antiviral effect of 1-aminoadamantane derivatives in vitro.", "content": "Antiviral effect of 1-aminoadamantane derivatives in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361336"}
{"pmid": "4361337", "title": "The National Center for Health Statistics. A research resource for pediatricians.", "content": "The National Center for Health Statistics. A research resource for pediatricians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361337"}
{"pmid": "4361338", "title": "Use of oxandrolone for growth stimulation in children.", "content": "Use of oxandrolone for growth stimulation in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361338"}
{"pmid": "4361341", "title": "A new look at the brain-damaged adult.", "content": "A new look at the brain-damaged adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361341"}
{"pmid": "4361339", "title": "Herpesvirus hominis infections in the fetus and the newborn.", "content": "Herpesvirus hominis infections in the fetus and the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361339"}
{"pmid": "4361346", "title": "The process of collaboration. II. Implementation and its discontents or you don't learn that in school.", "content": "The process of collaboration. II. Implementation and its discontents or you don't learn that in school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361346"}
{"pmid": "4361347", "title": "Incorporation and replication of foreign metaphase chromosomes in cultured mammalian cells.", "content": "Incorporation and replication of foreign metaphase chromosomes in cultured mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361347"}
{"pmid": "4361348", "title": "Colony formation of mammalian cells on agar plates and its application to Lederberg's replica plating.", "content": "Colony formation of mammalian cells on agar plates and its application to Lederberg's replica plating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361348"}
{"pmid": "4361349", "title": "c-AMP and the cell cycle: inhibition of growth stimulation.", "content": "c-AMP and the cell cycle: inhibition of growth stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361349"}
{"pmid": "4361351", "title": "The federal role in health: a conversation with Charles C. Edwards, M.D., assistant Secretary for Health, Department of Health, Education, and Welfare.", "content": "The federal role in health: a conversation with Charles C. Edwards, M.D., assistant Secretary for Health, Department of Health, Education, and Welfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361351"}
{"pmid": "4361353", "title": "Effect of induced interferon in experimental rhinovirus infections in volunteers.", "content": "Effect of induced interferon in experimental rhinovirus infections in volunteers. Nasal administration of an interferon inducer, CP-20,961 (N, N-dioctadecyl-N', N'-bis(2-hydroxyethyl)propanediamine), was evaluated in a double-blind, placebo-controlled study of experimental rhinovirus infection in 29 volunteers. Detectable nasal interferon developed in 10 of 15 subjects treated with CP-20,961, and 2 of 14 in the group receiving placebo (P < 0.006). Titers of CP-20,961-induced interferon ranged from 10 to 250 international units, concentrations similar to those observed in rhinovirus infections. Ten in the CP-20,961 group and eight in the placebo group became ill (P > 0.05). However, mean total sign scores were significantly diminished among CP-20,961-treated subjects as compared with placebo-treated subjects (P < 0.025). No significant effect was noted on quantitative virus shedding patterns or neutralizing antibody responses. These findings suggest that such concentrations of induced interferon do not protect against rhinovirus infection, and that factors other than interferon may be important in recovery from rhinovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361353"}
{"pmid": "4361355", "title": "Prevention of malnutrition.", "content": "Prevention of malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361355"}
{"pmid": "4361356", "title": "Prospects for decline in population growth in the developing nations.", "content": "Prospects for decline in population growth in the developing nations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361356"}
{"pmid": "4361354", "title": "Attenuation of rhinovirus type 15: relation of illness to plaque size.", "content": "Attenuation of rhinovirus type 15: relation of illness to plaque size. Rhinovirus type 15 passaged three times in WI-38 cells produced illness in only one of 35 volunteers, but infection resulted in formation of significant quantities of antibodies in the serums of 100%, and in nasal secretions of 89%, of infected volunteers. The inoculum contained large- (60%) and small- (40%) plaque variants. \"Purified\" large- and small-plaque inocula were prepared, and each was administered to 20 volunteers. There was a significant association of illness with the small-plaque inocula (P < 0.01) but the incidence of infection, quantitative virus shedding patterns, and mean serum and nasal secretory antibodies were not significantly different between the two groups. These findings suggest that plaque size may be an in vitro marker of attenuation of illness production by rhinoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361354"}
{"pmid": "4361343", "title": "The excitable membrane-biophysical theory and experiment.", "content": "The excitable membrane-biophysical theory and experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361343"}
{"pmid": "4361357", "title": "Acceptance of Elizabeth Blackwell Award.", "content": "Acceptance of Elizabeth Blackwell Award.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361357"}
{"pmid": "4361358", "title": "A new era: challenges for the woman physician. (Hey, no fair. There are hardly any lady doctors.).", "content": "A new era: challenges for the woman physician. (Hey, no fair. There are hardly any lady doctors.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361358"}
{"pmid": "4361359", "title": "Fluorescence studies of possible protein-protein interactions in model lipoprotein complexes.", "content": "Fluorescence studies of possible protein-protein interactions in model lipoprotein complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361359"}
{"pmid": "4361360", "title": "Cell agglutination mediated by concanavalin A and the dynamic state of the cell surface.", "content": "Cell agglutination mediated by concanavalin A and the dynamic state of the cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361360"}
{"pmid": "4361361", "title": "Initiation of DNA replication in mammalian cells and its inhibition by reovirus infection.", "content": "Initiation of DNA replication in mammalian cells and its inhibition by reovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361361"}
{"pmid": "4361363", "title": "Early components of the averaged electroencephalic response to constant level clicks during all-night sleep.", "content": "Early components of the averaged electroencephalic response to constant level clicks during all-night sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361363"}
{"pmid": "4361362", "title": "The enzymic make-up of the left and right ventricles of the normal rat heart and the changes shown on exposure to exercise and hypoxic exercise.", "content": "The enzymic make-up of the left and right ventricles of the normal rat heart and the changes shown on exposure to exercise and hypoxic exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361362"}
{"pmid": "4361364", "title": "Consequences of excess hormonal secretion in digestive disease.", "content": "Consequences of excess hormonal secretion in digestive disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361364"}
{"pmid": "4361352", "title": "The role of phosphorylation in the uptake of thymidine in mammalian cells.", "content": "The role of phosphorylation in the uptake of thymidine in mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361352"}
{"pmid": "4361370", "title": "Separation and radioimmunoassay of f alpha prostaglandins using silica gel micro columns.", "content": "Separation and radioimmunoassay of f alpha prostaglandins using silica gel micro columns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361370"}
{"pmid": "4361371", "title": "Stimulatory effects of prostaglandin e-1 on rat anterior pituitary cyclic AMP and luteinizing hormone release.", "content": "Stimulatory effects of prostaglandin e-1 on rat anterior pituitary cyclic AMP and luteinizing hormone release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361371"}
{"pmid": "4361368", "title": "Induction of liver tumours in rats by a single treatment with nitroso compounds given after partial hepatectomy.", "content": "Induction of liver tumours in rats by a single treatment with nitroso compounds given after partial hepatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361368"}
{"pmid": "4361372", "title": "TRH and prostaglandin action on rat anterior pituitary: dissociation between cyclic AMP levels and TSH release.", "content": "TRH and prostaglandin action on rat anterior pituitary: dissociation between cyclic AMP levels and TSH release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361372"}
{"pmid": "4361373", "title": "Prostaglandins and cyclic nucleotides in Moloney sarcoma tumors.", "content": "Prostaglandins and cyclic nucleotides in Moloney sarcoma tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361373"}
{"pmid": "4361374", "title": "Granular cell myoblastoma of the esophagus.", "content": "Granular cell myoblastoma of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361374"}
{"pmid": "4361380", "title": "Propagation of some common viruses in human embryonic brain cells.", "content": "Propagation of some common viruses in human embryonic brain cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361380"}
{"pmid": "4361381", "title": "Clear-cell carcinoma of the liver. A clinicopathologic study of 13 patients.", "content": "Clear-cell carcinoma of the liver. A clinicopathologic study of 13 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361381"}
{"pmid": "4361382", "title": "Acquired cytomegalovirus infection presenting as viral endometritis.", "content": "Acquired cytomegalovirus infection presenting as viral endometritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361382"}
{"pmid": "4361384", "title": "Proceedings: Carcinoma of the soft palate and uvula.", "content": "Proceedings: Carcinoma of the soft palate and uvula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361384"}
{"pmid": "4361383", "title": "Non-chromaffin paragangliomatosis manifesting as a cold thyroid nodule.", "content": "Non-chromaffin paragangliomatosis manifesting as a cold thyroid nodule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361383"}
{"pmid": "4361385", "title": "Proceedings: Serum alpha-fetoprotein and Ga67 citrate uptake in hepatoma.", "content": "Proceedings: Serum alpha-fetoprotein and Ga67 citrate uptake in hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361385"}
{"pmid": "4361386", "title": "Proceedings: Arteriography in insulinoma.", "content": "Proceedings: Arteriography in insulinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361386"}
{"pmid": "4361387", "title": "Multiple primary bronchogenic carcinoma with a review of the literature.", "content": "Multiple primary bronchogenic carcinoma with a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361387"}
{"pmid": "4361388", "title": "Ozone effect on respiratory deposition of vesicular stomatitis virus aerosols.", "content": "Ozone effect on respiratory deposition of vesicular stomatitis virus aerosols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361388"}
{"pmid": "4361389", "title": "Beclomethasone in childhood asthma.", "content": "Beclomethasone in childhood asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361389"}
{"pmid": "4361390", "title": "Pulmonary infections complicating treatment of multiple sclerosis. Occurrence with administration of corticotropin or adrenal steroids.", "content": "Pulmonary infections complicating treatment of multiple sclerosis. Occurrence with administration of corticotropin or adrenal steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361390"}
{"pmid": "4361391", "title": "Reye syndrome. An association with type I vaccine-like poliovirus.", "content": "Reye syndrome. An association with type I vaccine-like poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361391"}
{"pmid": "4361392", "title": "Parainfluenza, histocompatibility, and multiple sclerosis. Association of parainfluenza antibodies and histocompatibility types in MS and optic neuritis.", "content": "Parainfluenza, histocompatibility, and multiple sclerosis. Association of parainfluenza antibodies and histocompatibility types in MS and optic neuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361392"}
{"pmid": "4361393", "title": "Genetic heterogeneity of hereditary sensory neuropathy.", "content": "Genetic heterogeneity of hereditary sensory neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361393"}
{"pmid": "4361394", "title": "MU-chain disease in an African patient.", "content": "MU-chain disease in an African patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361394"}
{"pmid": "4361395", "title": "Hemoglobin Duarte: (alpha2beta2 62(E6)Ala leads to Pro): a new unstable hemoglobin with increased oxygen affinity.", "content": "Hemoglobin Duarte: (alpha2beta2 62(E6)Ala leads to Pro): a new unstable hemoglobin with increased oxygen affinity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361395"}
{"pmid": "4361397", "title": "Importance of central catecholaminergic neurones in the development and maintenance of renal hypertension.", "content": "Importance of central catecholaminergic neurones in the development and maintenance of renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361397"}
{"pmid": "4361399", "title": "Metabolic clearance rate of angiotensin II in arterial hypertension.", "content": "Metabolic clearance rate of angiotensin II in arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361399"}
{"pmid": "4361398", "title": "Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.", "content": "Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361398"}
{"pmid": "4361400", "title": "Synthesis of renin inhibitors.", "content": "Synthesis of renin inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361400"}
{"pmid": "4361402", "title": "Effects of angiotensin II on adenylcyclase activity, phosphodiesterase activity and on the level of cyclic AMP in rat uterus.", "content": "Effects of angiotensin II on adenylcyclase activity, phosphodiesterase activity and on the level of cyclic AMP in rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361402"}
{"pmid": "4361403", "title": "Angiotensin-salt hypertension.", "content": "Angiotensin-salt hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361403"}
{"pmid": "4361405", "title": "Plasma renin activity and plasma renin substrate in hypertension associated with steroid excess.", "content": "Plasma renin activity and plasma renin substrate in hypertension associated with steroid excess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361405"}
{"pmid": "4361404", "title": "Experimental studies on the mechanism of adrenocorticotrophic hormone-induced hypertension in the sheep.", "content": "Experimental studies on the mechanism of adrenocorticotrophic hormone-induced hypertension in the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361404"}
{"pmid": "4361406", "title": "Oral contraceptives and hypertension.", "content": "Oral contraceptives and hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361406"}
{"pmid": "4361401", "title": "Renin release and renal vasomotor changes during stimulation of the brain stem in the cat.", "content": "Renin release and renal vasomotor changes during stimulation of the brain stem in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361401"}
{"pmid": "4361407", "title": "Diseases and surgery of the nose.", "content": "Diseases and surgery of the nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361407"}
{"pmid": "4361408", "title": "Hormonal profiling in the diagnosis and treatment of essential hypertension.", "content": "Hormonal profiling in the diagnosis and treatment of essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361408"}
{"pmid": "4361409", "title": "Effects of diphenylhydantoin upon glucose-induced insulin secretion in three patients with insulinoma.", "content": "Effects of diphenylhydantoin upon glucose-induced insulin secretion in three patients with insulinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361409"}
{"pmid": "4361410", "title": "Insulin receptors in human and animal placental tissue.", "content": "Insulin receptors in human and animal placental tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361410"}
{"pmid": "4361411", "title": "Cytologic and functional changes in the adrenal cell culture from a human fetus under the action of o, p1-DDD. I. Morphological study.", "content": "Cytologic and functional changes in the adrenal cell culture from a human fetus under the action of o, p1-DDD. I. Morphological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361411"}
{"pmid": "4361412", "title": "Cytologic and functional changes in the adrenal cell culture from a human fetus under the action of o, p1-DDD. II. Study of corticosteroid production.", "content": "Cytologic and functional changes in the adrenal cell culture from a human fetus under the action of o, p1-DDD. II. Study of corticosteroid production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361412"}
{"pmid": "4361414", "title": "Affinity chromatography on immobilised adenosine 5'-monophosphate. 3. The binding of glycerokinase and lactate dehydrogenase in relation to column geometry and dynamics.", "content": "Affinity chromatography on immobilised adenosine 5'-monophosphate. 3. The binding of glycerokinase and lactate dehydrogenase in relation to column geometry and dynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361414"}
{"pmid": "4361413", "title": "Comparative studies on the template-initiator requirements of the chick-embryo DNA polymerase I and the avian-myeloblastosis-virus DNA polymerase.", "content": "Comparative studies on the template-initiator requirements of the chick-embryo DNA polymerase I and the avian-myeloblastosis-virus DNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361413"}
{"pmid": "4361415", "title": "Affinity chromatography on immobilised adenosine 5'-monophosphate. 4. Variation of the binding of dehydrogenases and kinases with pH.", "content": "Affinity chromatography on immobilised adenosine 5'-monophosphate. 4. Variation of the binding of dehydrogenases and kinases with pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361415"}
{"pmid": "4361416", "title": "Affinity chromatography on immobilised adenosine 5'-monophosphate. 5. Some applications of the influence of temperature on the binding of dehydrogenases and kinases.", "content": "Affinity chromatography on immobilised adenosine 5'-monophosphate. 5. Some applications of the influence of temperature on the binding of dehydrogenases and kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361416"}
{"pmid": "4361418", "title": "Animal DNA-dependent RNA polymerases. Analysis of the RNAs synthesized on Simian virus 40 superhelical DNA by mammalian RNA polymerases AI and B.", "content": "Animal DNA-dependent RNA polymerases. Analysis of the RNAs synthesized on Simian virus 40 superhelical DNA by mammalian RNA polymerases AI and B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361418"}
{"pmid": "4361417", "title": "Animal DNA-dependent RNA polymerases. Studies on the reaction parameters of transcription in vitro of Simian virus 40 DNA by mammalian RNA polymerases AI and B.", "content": "Animal DNA-dependent RNA polymerases. Studies on the reaction parameters of transcription in vitro of Simian virus 40 DNA by mammalian RNA polymerases AI and B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361417"}
{"pmid": "4361420", "title": "Inhibition of spontaneous aggregation by wheat germ agglutinin in suspensions of BALB-C-3T3 and BHK21 tissue culture fibroblasts.", "content": "Inhibition of spontaneous aggregation by wheat germ agglutinin in suspensions of BALB-C-3T3 and BHK21 tissue culture fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361420"}
{"pmid": "4361419", "title": "Animal DNA-dependent RNA polymerases. Studies on the binding of mammalian RNA polymerases AI and B to Simian virus 40 DNA.", "content": "Animal DNA-dependent RNA polymerases. Studies on the binding of mammalian RNA polymerases AI and B to Simian virus 40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361419"}
{"pmid": "4361423", "title": "Cyclic AMP dependent regulation of mitosis in human lymphoid cells.", "content": "Cyclic AMP dependent regulation of mitosis in human lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361423"}
{"pmid": "4361421", "title": "Synthesis of DNA-binding protein in WI-38 cells stimulated to synthesize DNA by medium replacement.", "content": "Synthesis of DNA-binding protein in WI-38 cells stimulated to synthesize DNA by medium replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361421"}
{"pmid": "4361422", "title": "Thymidine transport by Novikoff rat hepatoma cells synchronized by double hydroxyurea treatment.", "content": "Thymidine transport by Novikoff rat hepatoma cells synchronized by double hydroxyurea treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361422"}
{"pmid": "4361425", "title": "Myogenesis in vitro. Enhancement by dibutyryl cAMP.", "content": "Myogenesis in vitro. Enhancement by dibutyryl cAMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361425"}
{"pmid": "4361424", "title": "Tes and HEPES buffers in mammalian cell cultures and viral studies: problem of carbon dioxide requirement.", "content": "Tes and HEPES buffers in mammalian cell cultures and viral studies: problem of carbon dioxide requirement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361424"}
{"pmid": "4361426", "title": "Chromatin fractionation of normal and virus-transformed cells in culture.", "content": "Chromatin fractionation of normal and virus-transformed cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361426"}
{"pmid": "4361428", "title": "Pneumoconiosis.", "content": "Pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361428"}
{"pmid": "4361427", "title": "Chemical labeling and freeze-fracture studies on the localization of rhodopsin in the rod outer segment disk membrane.", "content": "Chemical labeling and freeze-fracture studies on the localization of rhodopsin in the rod outer segment disk membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361427"}
{"pmid": "4361429", "title": "Prolonged administration of Penicillium viridicatum to mice: preliminary report of carcinogenicity.", "content": "Prolonged administration of Penicillium viridicatum to mice: preliminary report of carcinogenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361429"}
{"pmid": "4361430", "title": "Corticosteroid therapy in corneal disease. I.", "content": "Corticosteroid therapy in corneal disease. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361430"}
{"pmid": "4361432", "title": "Current therapy of herpes simplex virus infection of the cornea.", "content": "Current therapy of herpes simplex virus infection of the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361432"}
{"pmid": "4361434", "title": "Investigations on serum lipid components and serum vitamin E in iron deficiency anemia.", "content": "Investigations on serum lipid components and serum vitamin E in iron deficiency anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361434"}
{"pmid": "4361431", "title": "Treatment of corneal ulcers with collagenase inhibitors.", "content": "Treatment of corneal ulcers with collagenase inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361431"}
{"pmid": "4361433", "title": "In vitro phosphate transport in chick ileum: effect of cholecalciferol, calcium, sodium and metabolic inhibitors.", "content": "In vitro phosphate transport in chick ileum: effect of cholecalciferol, calcium, sodium and metabolic inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361433"}
{"pmid": "4361435", "title": "Fluctuation of the nucleotide pools of flavinogenic and nonflavinogenic strains of Eremothecium ashbyii grown in the presence of purines.", "content": "Fluctuation of the nucleotide pools of flavinogenic and nonflavinogenic strains of Eremothecium ashbyii grown in the presence of purines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361435"}
{"pmid": "4361436", "title": "Cyclic adenosine 3':5'-monophosphate and protein kinase levels in developing bovine spermatozoa.", "content": "Cyclic adenosine 3':5'-monophosphate and protein kinase levels in developing bovine spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361436"}
{"pmid": "4361438", "title": "Letter: Estrogen binding in breast cancer.", "content": "Letter: Estrogen binding in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361438"}
{"pmid": "4361440", "title": "Prevention of gestational trophoblastic disease by use of actinomycin D in molar pregnancies.", "content": "Prevention of gestational trophoblastic disease by use of actinomycin D in molar pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361440"}
{"pmid": "4361439", "title": "Inclusion-body beta-thalassemia trait. A form of beta thalassemia producing clinical manifestations in simple heterozygotes.", "content": "Inclusion-body beta-thalassemia trait. A form of beta thalassemia producing clinical manifestations in simple heterozygotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361439"}
{"pmid": "4361442", "title": "Arrhenoblastomas and associated ovarian pathology.", "content": "Arrhenoblastomas and associated ovarian pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361442"}
{"pmid": "4361443", "title": "A new oral amoebicid (RO 7-0207) in the treatment of intestinal amoebiasis.", "content": "A new oral amoebicid (RO 7-0207) in the treatment of intestinal amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361443"}
{"pmid": "4361441", "title": "Arrhenoblastoma associated with adrenal androgenic hyperfunction.", "content": "Arrhenoblastoma associated with adrenal androgenic hyperfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361441"}
{"pmid": "4361446", "title": "Chemistry and biologic activity of the complement system.", "content": "Chemistry and biologic activity of the complement system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361446"}
{"pmid": "4361447", "title": "Synthesis and metabolism of complement proteins.", "content": "Synthesis and metabolism of complement proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361447"}
{"pmid": "4361448", "title": "Editorial: Implications of equine virus abortion.", "content": "Editorial: Implications of equine virus abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361448"}
{"pmid": "4361451", "title": "Morphologic revertants of murine sarcoma virus transformed nonproducer BALB-3T3: selective techniques for isolation and biologic properties in vitro and in vivo.", "content": "Morphologic revertants of murine sarcoma virus transformed nonproducer BALB-3T3: selective techniques for isolation and biologic properties in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361451"}
{"pmid": "4361450", "title": "Cell killing by viruses. I. Comparison of cell-killing, plaque-forming, and defective-interfering particles of vesicular stomatitis virus.", "content": "Cell killing by viruses. I. Comparison of cell-killing, plaque-forming, and defective-interfering particles of vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361450"}
{"pmid": "4361452", "title": "Conditional lethal mutants of vesicular stomatitis virus. I. Phenotypic characterization of single and double mutants exhibiting host restriction and temperature sensitivity.", "content": "Conditional lethal mutants of vesicular stomatitis virus. I. Phenotypic characterization of single and double mutants exhibiting host restriction and temperature sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361452"}
{"pmid": "4361453", "title": "Conditional lethal mutants of vesicular stomatitis virus. II. Synthesis of virus-specific polypeptides in nonpermissive cells infected with \"RNA-\" host-restricted mutants.", "content": "Conditional lethal mutants of vesicular stomatitis virus. II. Synthesis of virus-specific polypeptides in nonpermissive cells infected with \"RNA-\" host-restricted mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361453"}
{"pmid": "4361454", "title": "The molecular size of the herpes simplex virus type 1 genome.", "content": "The molecular size of the herpes simplex virus type 1 genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361454"}
{"pmid": "4361456", "title": "Interferon production by individual cells.", "content": "Interferon production by individual cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361456"}
{"pmid": "4361457", "title": "Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive precursor protein of Sendai virus.", "content": "Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive precursor protein of Sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361457"}
{"pmid": "4361458", "title": "An improved murine leukemia virus immunofluorescence assay.", "content": "An improved murine leukemia virus immunofluorescence assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361458"}
{"pmid": "4361459", "title": "Structure of the Mengo virion. I. Polypeptide and ribonucleate components of the virus particle.", "content": "Structure of the Mengo virion. I. Polypeptide and ribonucleate components of the virus particle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361459"}
{"pmid": "4361461", "title": "In vitro association of vesicular stomatitis virus proteins with purified HeLa and erythrocyte plasma membranes.", "content": "In vitro association of vesicular stomatitis virus proteins with purified HeLa and erythrocyte plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361461"}
{"pmid": "4361460", "title": "Isolation, complementation and preliminary phenotypic characterization of temperature-sensitive mutants of herpes simplex virus type 2.", "content": "Isolation, complementation and preliminary phenotypic characterization of temperature-sensitive mutants of herpes simplex virus type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361460"}
{"pmid": "4361455", "title": "Antigens specified by herpesviruses. 3. Viral-induced nuclear polypeptides.", "content": "Antigens specified by herpesviruses. 3. Viral-induced nuclear polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361455"}
{"pmid": "4361462", "title": "Therapy of herpes simplex with heat inactivated Herpes virus hominis type 1 and type 2.", "content": "Therapy of herpes simplex with heat inactivated Herpes virus hominis type 1 and type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361462"}
{"pmid": "4361464", "title": "Effect on steroid metabolism of STC-407 and cyproterone acetate in female hirsutism.", "content": "Effect on steroid metabolism of STC-407 and cyproterone acetate in female hirsutism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361464"}
{"pmid": "4361465", "title": "Plasma free fatty acid and acute vascular injury.", "content": "Plasma free fatty acid and acute vascular injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361465"}
{"pmid": "4361466", "title": "Cholangiocarcinoma with hypercalcemia--a case report studied by electron-microscope and radioimmunoassay.", "content": "Cholangiocarcinoma with hypercalcemia--a case report studied by electron-microscope and radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361466"}
{"pmid": "4361468", "title": "Determination of the amount of bone in the metacarpal.", "content": "Determination of the amount of bone in the metacarpal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361468"}
{"pmid": "4361470", "title": "Should we always keep controlling?", "content": "Should we always keep controlling?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361470"}
{"pmid": "4361467", "title": "Diet and bone rarefaction in old age.", "content": "Diet and bone rarefaction in old age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361467"}
{"pmid": "4361469", "title": "Editorial: Viruses and arteriosclerosis.", "content": "Editorial: Viruses and arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361469"}
{"pmid": "4361471", "title": "Finite level models of biological systems.", "content": "Finite level models of biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361471"}
{"pmid": "4361475", "title": "Glioblastoma of the optic chiasm.", "content": "Glioblastoma of the optic chiasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361475"}
{"pmid": "4361473", "title": "The radiological importance of soft-tissue lesions related to the skeleton.", "content": "The radiological importance of soft-tissue lesions related to the skeleton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361473"}
{"pmid": "4361476", "title": "Cullen's sign, a feature in liver disease.", "content": "Cullen's sign, a feature in liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361476"}
{"pmid": "4361478", "title": "An aphasic syndrome in children.", "content": "An aphasic syndrome in children. The paper presents case reports of nine children, all of whom had severe disturbances of language function of abrupt or gradual onset. Seizures occurred in seven of the children and all nine had EEG abnormalities.There was no apparent correlation between the seizures, the EEG changes and the aphasia. One patient had a brain biopsy performed at another hospital and the tissue was said to be normal. The cause of the abnormal language function is unknown. Five of the children failed to acquire normal speech subsequently. Three of the four children who made a complete recovery were treated with steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361478"}
{"pmid": "4361479", "title": "The structure of a dextran produced by Leuconostoc mesenteroides NRRL B-1397: the linkages and length of the branches.", "content": "The structure of a dextran produced by Leuconostoc mesenteroides NRRL B-1397: the linkages and length of the branches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361479"}
{"pmid": "4361483", "title": "Proceedings: Unsaturated fat and plasma triglyceride metabolism in man.", "content": "Proceedings: Unsaturated fat and plasma triglyceride metabolism in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361483"}
{"pmid": "4361482", "title": "Proceedings: The effects of exogenous parathyroid hormone on circulating adenosine 3':5' monophosphate in man.", "content": "Proceedings: The effects of exogenous parathyroid hormone on circulating adenosine 3':5' monophosphate in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361482"}
{"pmid": "4361484", "title": "The pressor response to intravenously infused angiotensin II: correlation with plasma renin activity.", "content": "The pressor response to intravenously infused angiotensin II: correlation with plasma renin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361484"}
{"pmid": "4361487", "title": "Action of angiotensin antagonists and antiserum upon the pressor response to renin: further evidence for the local generation of angiotensin II.", "content": "Action of angiotensin antagonists and antiserum upon the pressor response to renin: further evidence for the local generation of angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361487"}
{"pmid": "4361485", "title": "Proceedings: Inhibition of adenyl cyclase by a bacterial exotoxin.", "content": "Proceedings: Inhibition of adenyl cyclase by a bacterial exotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361485"}
{"pmid": "4361488", "title": "The charade of poverty funding for community mental health centers.", "content": "The charade of poverty funding for community mental health centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361488"}
{"pmid": "4361486", "title": "Competitive protein-binding assay for 25-hydroxycholecalciferol.", "content": "Competitive protein-binding assay for 25-hydroxycholecalciferol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361486"}
{"pmid": "4361480", "title": "Comparison of pelvic osteotomies for the surgical correction of the congenital hip.", "content": "Comparison of pelvic osteotomies for the surgical correction of the congenital hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361480"}
{"pmid": "4361491", "title": "Short-term heroin detoxification on an outpatient basis.", "content": "Short-term heroin detoxification on an outpatient basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361491"}
{"pmid": "4361493", "title": "Fibroblast collagenase partial purification and characterization.", "content": "Fibroblast collagenase partial purification and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361493"}
{"pmid": "4361490", "title": "A serological study on the occurrence of some respiratory infections in Fiji.", "content": "A serological study on the occurrence of some respiratory infections in Fiji.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361490"}
{"pmid": "4361492", "title": "Corneal ulceration and the serum antiproteases. I. Alpha 1-antitrypsin.", "content": "Corneal ulceration and the serum antiproteases. I. Alpha 1-antitrypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361492"}
{"pmid": "4361489", "title": "Proceedings: Molecular aspects in comparative endocrinology.", "content": "Proceedings: Molecular aspects in comparative endocrinology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361489"}
{"pmid": "4361495", "title": "The \"new\" vegetarians. Group affiliation and dietary strictures related to attitudes and life style.", "content": "The \"new\" vegetarians. Group affiliation and dietary strictures related to attitudes and life style.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361495"}
{"pmid": "4361494", "title": "Corneal toxicity of collagenase inhibitors.", "content": "Corneal toxicity of collagenase inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361494"}
{"pmid": "4361496", "title": "Vitamin E: relationship to thyroxine in man.", "content": "Vitamin E: relationship to thyroxine in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361496"}
{"pmid": "4361497", "title": "An experiment in liaison psychiatry to a community health center.", "content": "An experiment in liaison psychiatry to a community health center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361497"}
{"pmid": "4361498", "title": "Sudden infant death syndrome: an epidemiologic study.", "content": "Sudden infant death syndrome: an epidemiologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361498"}
{"pmid": "4361499", "title": "A biologically active insulin analog with an enlarged intrachain cyclic system.", "content": "A biologically active insulin analog with an enlarged intrachain cyclic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361499"}
{"pmid": "4361481", "title": "The role of the kidney and vitamin D metabolism in health and disease.", "content": "The role of the kidney and vitamin D metabolism in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361481"}
{"pmid": "4361500", "title": "Susceptibility of the VERO line of African green monkey kidney cells to human enteroviruses.", "content": "Susceptibility of the VERO line of African green monkey kidney cells to human enteroviruses. The relative susceptibility of VERO cells and primary rhesus monkey kidney cells to 47 prototype strains of human enteroviruses is described. Of these strains, types 4, 14, 16, 17, 18, 21, 31 and 34 and Coxsackie virus A 9 failed to cause CPE in the VERO cells whilst only one, echovirus type 34, failed to cause CPE in the monkey kidney cells.A comparison is given of the efficiency of the two cell cultures for enterovirus isolation from clinical material. Results show that VERO cells are as useful as primary monkey kidney for the isolation of Coxsackie B viruses but less satisfactory for isolating echoviruses. They are satisfactory for the isolation of single types of poliovirus and appear to be more satisfactory than primary monkey kidney cells for the isolation of mixtures of polioviruses. The identification of enteroviruses by neutralization tests in VERO cells is successful.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361500"}
{"pmid": "4361501", "title": "The airborne excretion by pigs of swine vesicular disease virus.", "content": "The airborne excretion by pigs of swine vesicular disease virus. The air of loose-boxes holding pigs affected with swine vesicular disease was sampled for virus. In the multistage impinger virus to a titre of 10(2.6) TCID 50 was associated with particles greater than 6 mum., 10(1.6) with particles 3-6 mum. and 10(1.4) or less with particles less than 3 mum. In the noses of workers in contact with the pigs for periods not less than 5 min., virus to a titre of 10(2.4) TCID 50 was found. Virus was recovered from the air for 2-3 days during the disease and maximum titre in pigs infected by injection or by contact occurred on the second to third day after generalization of the lesions. The amounts of virus were about 160-fold less than those recovered from pigs affected with foot-and-mouth disease, and the quantity and time of excretion suggest that the source of swine vesicular disease virus in the aerosol may be from the lesions and skin rather than from the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361501"}
{"pmid": "4361503", "title": "Arbovirus serology in North Dakota mule and white-tailed deer.", "content": "Arbovirus serology in North Dakota mule and white-tailed deer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361503"}
{"pmid": "4361504", "title": "A study of reproduction, disease and physiological blood and serum values in Idaho elk.", "content": "A study of reproduction, disease and physiological blood and serum values in Idaho elk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361504"}
{"pmid": "4361502", "title": "Antibody responses in patients with farmer's lung disease to antigens from Micropolyspora faeni.", "content": "Antibody responses in patients with farmer's lung disease to antigens from Micropolyspora faeni. Three purified cell-wall glycoprotein antigens, a, b and c, sensitive to sodium periodate and resistant to pronase, were extracted from mycelium of Micropolyspora faeni with aqueous phenol or trichloracetic acid. Pronase-sensitive, sodium periodate-resistant protein antigens were extracted from mycelium with aqueous phenol. Immunoelectrophoresis was a critical method of assessing purity of preparation.Antibodies to glycoprotein antigens only occurred in clinically defined cases of farmer's lung disease, whereas antibodies to protein antigens also occurred in symptomless farmers. Precipitins to a occurred in all cases of farmer's lung disease, and this antigen was isolated and purified.Fractionation of pooled sera from cases of farmer's lung disease showed that precipitins were IgG globulins, whereas latex-agglutinating antibodies were IgG, IgA and especially IgM globulins. It is suggested that farmer's lung may involve a cytotoxic type II reaction, in which glycoproteins adsorbed to tissue cells react with IgG, IgA and IgM immunoglobulins in the presence of complement, causing cellular damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361502"}
{"pmid": "4361505", "title": "Vaccination of American bison against Pasteurella multocida serotype 2 infection (Hemorrhagic septicemia).", "content": "Vaccination of American bison against Pasteurella multocida serotype 2 infection (Hemorrhagic septicemia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361505"}
{"pmid": "4361506", "title": "Neutralization of channel catfish virus by serum of channel catfish.", "content": "Neutralization of channel catfish virus by serum of channel catfish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361506"}
{"pmid": "4361507", "title": "Electron microscopy of the virus of oral papillomatosis in the coyote.", "content": "Electron microscopy of the virus of oral papillomatosis in the coyote.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361507"}
{"pmid": "4361508", "title": "Cholesterol metabolism in the rat sensitive to high cholesterol diet.", "content": "Cholesterol metabolism in the rat sensitive to high cholesterol diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361508"}
{"pmid": "4361509", "title": "A fatal case of type 2 herpes simplex virus infection in a newborn.", "content": "A fatal case of type 2 herpes simplex virus infection in a newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361509"}
{"pmid": "4361510", "title": "Changes in back-transplantability by fluid-suspension culture and by long-term of cultivation of two tissue culture cell strains, JTC-1 and JTC-2, originated from rat ascites hepatoma AH-130.", "content": "Changes in back-transplantability by fluid-suspension culture and by long-term of cultivation of two tissue culture cell strains, JTC-1 and JTC-2, originated from rat ascites hepatoma AH-130.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361510"}
{"pmid": "4361511", "title": "Humoral cytotoxic factor in isograft immunity against azo-dye induced hepatoma.", "content": "Humoral cytotoxic factor in isograft immunity against azo-dye induced hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361511"}
{"pmid": "4361513", "title": "Primary hyperparathyroidism: clinical and biochemical features.", "content": "Primary hyperparathyroidism: clinical and biochemical features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361513"}
{"pmid": "4361517", "title": "Electron microscopy of bluetongue virus RNA.", "content": "Electron microscopy of bluetongue virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361517"}
{"pmid": "4361515", "title": "Foot-and-mouth disease in the african elephant (Loxodonta africana).", "content": "Foot-and-mouth disease in the african elephant (Loxodonta africana).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361515"}
{"pmid": "4361518", "title": "Total decompression of the facial nerve in osteopetrosis (marble bone disease-morbus Albers-Schönberg).", "content": "Total decompression of the facial nerve in osteopetrosis (marble bone disease-morbus Albers-Schönberg).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361518"}
{"pmid": "4361523", "title": "Hodgkin's disease: considerable progress and more to be achieved.", "content": "Hodgkin's disease: considerable progress and more to be achieved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361523"}
{"pmid": "4361525", "title": "Plasma cortisol and the use of hydrocortisone in the treatment of status asthmaticus.", "content": "Plasma cortisol and the use of hydrocortisone in the treatment of status asthmaticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361525"}
{"pmid": "4361524", "title": "Electron microscopy of chlorphentermine lung.", "content": "Electron microscopy of chlorphentermine lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361524"}
{"pmid": "4361526", "title": "Granular cell myoblastoma of the oesophagus.", "content": "Granular cell myoblastoma of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361526"}
{"pmid": "4361528", "title": "Studies in cholestasis of pregnancy with special reference to lipids and lipoproteins.", "content": "Studies in cholestasis of pregnancy with special reference to lipids and lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361528"}
{"pmid": "4361529", "title": "Cyclic nucleotide phosphodiesterases.", "content": "Cyclic nucleotide phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361529"}
{"pmid": "4361521", "title": "Certain examples of application of ascorbate in biochemical investigations.", "content": "Certain examples of application of ascorbate in biochemical investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361521"}
{"pmid": "4361530", "title": "Nonhuman primates in viral oncology.", "content": "Nonhuman primates in viral oncology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361530"}
{"pmid": "4361532", "title": "Intestinal diamine oxidase: isolation, substrate specificity and pathophysiological significance.", "content": "Intestinal diamine oxidase: isolation, substrate specificity and pathophysiological significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361532"}
{"pmid": "4361531", "title": "Comparison of the 14-C-putrescine assay with the NADH test for the determination of diamine oxidase: description of a standard procedure with a high precision and an improved accuracy.", "content": "Comparison of the 14-C-putrescine assay with the NADH test for the determination of diamine oxidase: description of a standard procedure with a high precision and an improved accuracy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361531"}
{"pmid": "4361534", "title": "The intimal proliferation in aortic-coronary saphenous vein grafts. Light and electron microscopic studies.", "content": "The intimal proliferation in aortic-coronary saphenous vein grafts. Light and electron microscopic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361534"}
{"pmid": "4361533", "title": "Copper heterogeneity in pig kidney histaminase. An EPR study on the effect of substrate, guanidine and mersalyl.", "content": "Copper heterogeneity in pig kidney histaminase. An EPR study on the effect of substrate, guanidine and mersalyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361533"}
{"pmid": "4361536", "title": "Cyclic adenosine monophosphate and clinical medicine. I.", "content": "Cyclic adenosine monophosphate and clinical medicine. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361536"}
{"pmid": "4361537", "title": "Effects of angiotensin I and angiotensin II on renal blood flow in sheep.", "content": "Effects of angiotensin I and angiotensin II on renal blood flow in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361537"}
{"pmid": "4361539", "title": "Determinants of systemic hydraulic power in unanesthetized dogs.", "content": "Determinants of systemic hydraulic power in unanesthetized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361539"}
{"pmid": "4361535", "title": "Intrauterine virus infections and congenital heart disease.", "content": "Intrauterine virus infections and congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361535"}
{"pmid": "4361538", "title": "Plasma 17-hydroxycorticosteroids and growth hormone during defense reactions.", "content": "Plasma 17-hydroxycorticosteroids and growth hormone during defense reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361538"}
{"pmid": "4361540", "title": "Effect of melanotropic peptides on protein synthesis in mouse brain.", "content": "Effect of melanotropic peptides on protein synthesis in mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361540"}
{"pmid": "4361541", "title": "An antimelanotropic protein in human cerebrospinal fluid.", "content": "An antimelanotropic protein in human cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361541"}
{"pmid": "4361543", "title": "Orbital space-occupying lesions. Four decades of Eye Hospital reports.", "content": "Orbital space-occupying lesions. Four decades of Eye Hospital reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361543"}
{"pmid": "4361545", "title": "Isolation and lipid composition of spinach chloroplast envelope membranes.", "content": "Isolation and lipid composition of spinach chloroplast envelope membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361545"}
{"pmid": "4361546", "title": "Purification and characterization of the Novikoff hepatoma glycogen phosphorylase and its relations to a fetal form.", "content": "Purification and characterization of the Novikoff hepatoma glycogen phosphorylase and its relations to a fetal form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361546"}
{"pmid": "4361548", "title": "Simultaneous measurement of oxidative phosphorylation and adenylate kinase in plant mitochondria.", "content": "Simultaneous measurement of oxidative phosphorylation and adenylate kinase in plant mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361548"}
{"pmid": "4361549", "title": "Structural requirements for the formation of ordered lipid multibilayers--a spin probe study.", "content": "Structural requirements for the formation of ordered lipid multibilayers--a spin probe study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361549"}
{"pmid": "4361550", "title": "Homotropic regulation of dihydrolipoyl dehydrogenase from bovine kidney.", "content": "Homotropic regulation of dihydrolipoyl dehydrogenase from bovine kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361550"}
{"pmid": "4361547", "title": "On the mechanism of a calcium-associated defect of oxidative phosphorylation in progessive muscular dystrophy.", "content": "On the mechanism of a calcium-associated defect of oxidative phosphorylation in progessive muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361547"}
{"pmid": "4361552", "title": "Enzymes of serine biosynthesis in Rhodopseudomonas capsulata.", "content": "Enzymes of serine biosynthesis in Rhodopseudomonas capsulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361552"}
{"pmid": "4361553", "title": "Respiratory changes induced by guanidines and cations in submitochondrial particles.", "content": "Respiratory changes induced by guanidines and cations in submitochondrial particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361553"}
{"pmid": "4361551", "title": "An assessment of some molecular parameters of mevalonate kinase from plant and animal sources.", "content": "An assessment of some molecular parameters of mevalonate kinase from plant and animal sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361551"}
{"pmid": "4361554", "title": "The oxidation-reduction potentials of electron carriers in chloroplast photosystem I fragments.", "content": "The oxidation-reduction potentials of electron carriers in chloroplast photosystem I fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361554"}
{"pmid": "4361555", "title": "Cholesterol uptake from doubly-labeled alpha-lipoproteins by cells in tissue culture.", "content": "Cholesterol uptake from doubly-labeled alpha-lipoproteins by cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361555"}
{"pmid": "4361544", "title": "Oat cell carcinoma of the larynx.", "content": "Oat cell carcinoma of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361544"}
{"pmid": "4361557", "title": "Enzymatic dehydrogenation of steroids by beta-hydroxysteroid dehydrogenase in a two-phase system.", "content": "Enzymatic dehydrogenation of steroids by beta-hydroxysteroid dehydrogenase in a two-phase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361557"}
{"pmid": "4361558", "title": "The mechanism of the diaphorase reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase.", "content": "The mechanism of the diaphorase reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361558"}
{"pmid": "4361556", "title": "The molecular reorganization of lipid bilayers by osmium tetroxide. A spin-label study of orientation and restricted y-axis anisotropic motion in model membrane systems.", "content": "The molecular reorganization of lipid bilayers by osmium tetroxide. A spin-label study of orientation and restricted y-axis anisotropic motion in model membrane systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361556"}
{"pmid": "4361559", "title": "Aspects of Epstein-Barr virus infection in childhood.", "content": "Aspects of Epstein-Barr virus infection in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361559"}
{"pmid": "4361542", "title": "Enzyme changes in diabetes mellitus.", "content": "Enzyme changes in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361542"}
{"pmid": "4361564", "title": "Radiosensitivity and the ascorbic acid electron spin resonance doublet.", "content": "Radiosensitivity and the ascorbic acid electron spin resonance doublet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361564"}
{"pmid": "4361563", "title": "Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by exogenous adenosine deaminase.", "content": "Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by exogenous adenosine deaminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361563"}
{"pmid": "4361565", "title": "Very low density lipoprotein \"remnant\" particles: uptake by aortic smooth muscle cells in culture.", "content": "Very low density lipoprotein \"remnant\" particles: uptake by aortic smooth muscle cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361565"}
{"pmid": "4361566", "title": "Effects of insulin on gluconeogenesis and cyclic AMP levels in perfused livers from diabetic rats.", "content": "Effects of insulin on gluconeogenesis and cyclic AMP levels in perfused livers from diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361566"}
{"pmid": "4361567", "title": "Effects of adrenalectomy and glucocorticoid replacement on gluconeogenesis in perfused livers from diabetic rats.", "content": "Effects of adrenalectomy and glucocorticoid replacement on gluconeogenesis in perfused livers from diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361567"}
{"pmid": "4361568", "title": "Vitamin D metabolites. Specific binding by rat intestinal cytosol.", "content": "Vitamin D metabolites. Specific binding by rat intestinal cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361568"}
{"pmid": "4361569", "title": "The role of calcium in fly salivary gland secretion analyzed with the ionophore A-23187.", "content": "The role of calcium in fly salivary gland secretion analyzed with the ionophore A-23187.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361569"}
{"pmid": "4361570", "title": "The development and present status of ultrasonic encephalography.", "content": "The development and present status of ultrasonic encephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361570"}
{"pmid": "4361571", "title": "Renal function during and after anaesthesia and surgery: significance for water and electrolyte management.", "content": "Renal function during and after anaesthesia and surgery: significance for water and electrolyte management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361571"}
{"pmid": "4361562", "title": "Hearing levels in Nigerian ataxic neuropathy.", "content": "Hearing levels in Nigerian ataxic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361562"}
{"pmid": "4361560", "title": "Neuro-audiological correlates in cerebral hemisphere lesions. Temporal and parietal lobe tumors.", "content": "Neuro-audiological correlates in cerebral hemisphere lesions. Temporal and parietal lobe tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361560"}
{"pmid": "4361572", "title": "Chlamydial infections of the cervix.", "content": "Chlamydial infections of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361572"}
{"pmid": "4361575", "title": "Sexually transmitted diseases. Extract from the Annual Report of the Chief Medical Officer of the Department of Health and Social Security for the year 1972.", "content": "Sexually transmitted diseases. Extract from the Annual Report of the Chief Medical Officer of the Department of Health and Social Security for the year 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361575"}
{"pmid": "4361573", "title": "Chlamydia A in the female genital tract.", "content": "Chlamydia A in the female genital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361573"}
{"pmid": "4361574", "title": "Ultrastructural characteristics of Trichomonas vaginalis. An electron microscopical study.", "content": "Ultrastructural characteristics of Trichomonas vaginalis. An electron microscopical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361574"}
{"pmid": "4361576", "title": "The role of infection in the morbidity of asthmatic children admitted to hospital.", "content": "The role of infection in the morbidity of asthmatic children admitted to hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361576"}
{"pmid": "4361580", "title": "Proceedings: Virological aspects.", "content": "Proceedings: Virological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361580"}
{"pmid": "4361579", "title": "Proceedings: Aspects of EB virus infection.", "content": "Proceedings: Aspects of EB virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361579"}
{"pmid": "4361581", "title": "Proceedings: EB virus and other diseases.", "content": "Proceedings: EB virus and other diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361581"}
{"pmid": "4361582", "title": "Gentamicin:adenine mononucleotide transferase: partial purification, characterization, and use in the clinical quantitation of gentamicin.", "content": "Gentamicin:adenine mononucleotide transferase: partial purification, characterization, and use in the clinical quantitation of gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361582"}
{"pmid": "4361583", "title": "Cyclic production of vesicular stomatitis virus caused by defective interfering particles.", "content": "Cyclic production of vesicular stomatitis virus caused by defective interfering particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361583"}
{"pmid": "4361584", "title": "Three Yugoslav herpes simplex viruses: biologic and antigenic properties and formation of giant cells in vitro by a cervical isolate.", "content": "Three Yugoslav herpes simplex viruses: biologic and antigenic properties and formation of giant cells in vitro by a cervical isolate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361584"}
{"pmid": "4361585", "title": "Editorial: Recent contributions to the mechanism of action and clinical relevance of erythropoietin.", "content": "Editorial: Recent contributions to the mechanism of action and clinical relevance of erythropoietin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361585"}
{"pmid": "4361586", "title": "The lymphoreticular system and interferon production.", "content": "The lymphoreticular system and interferon production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361586"}
{"pmid": "4361587", "title": "Studies on the function of cell membrane. 8th report. Binding of cytochrome c to liver plasma membrane and microsome in CCl4-poisoned rats.", "content": "Studies on the function of cell membrane. 8th report. Binding of cytochrome c to liver plasma membrane and microsome in CCl4-poisoned rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361587"}
{"pmid": "4361561", "title": "Neuro-vestibular correlates in cerebral hemispheric lesions.", "content": "Neuro-vestibular correlates in cerebral hemispheric lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361561"}
{"pmid": "4361588", "title": "Studies on the function of cell membrane. 9th report. Protective action of sodium taurine N-carbodithioate (TDT) against CCl4-induced biochemical changes in liver cell membrane of rats.", "content": "Studies on the function of cell membrane. 9th report. Protective action of sodium taurine N-carbodithioate (TDT) against CCl4-induced biochemical changes in liver cell membrane of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361588"}
{"pmid": "4361589", "title": "Participation of muscarinic receptors on splanchnic-adrenal transmission in the rat.", "content": "Participation of muscarinic receptors on splanchnic-adrenal transmission in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361589"}
{"pmid": "4361591", "title": "Effect of cytochrome c on carbon tetrachloride damage to the liver.", "content": "Effect of cytochrome c on carbon tetrachloride damage to the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361591"}
{"pmid": "4361592", "title": "Effects of low concentrations of lithium chloride on adrenergic transmission in the isolated atria of rabbits.", "content": "Effects of low concentrations of lithium chloride on adrenergic transmission in the isolated atria of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361592"}
{"pmid": "4361590", "title": "Potentiation of the contractile response of isolated aortae to transmural stimulation by angiotensin.", "content": "Potentiation of the contractile response of isolated aortae to transmural stimulation by angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361590"}
{"pmid": "4361593", "title": "Anti-oxytocin actions of papaverine, aspaminol and isoprenaline on the rat uterus and intracellular cyclin adenosine 3,5-monophosphate level.", "content": "Anti-oxytocin actions of papaverine, aspaminol and isoprenaline on the rat uterus and intracellular cyclin adenosine 3,5-monophosphate level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361593"}
{"pmid": "4361595", "title": "The role of cyclic nucleotides in visual excitation.", "content": "The role of cyclic nucleotides in visual excitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361595"}
{"pmid": "4361596", "title": "The construction and use of quartz fiber fish pole balances.", "content": "The construction and use of quartz fiber fish pole balances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361596"}
{"pmid": "4361597", "title": "Oxidation states of peroxidase.", "content": "Oxidation states of peroxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361597"}
{"pmid": "4361599", "title": "Action of a serum protein in coupling excitation contraction of heart papillary muscle.", "content": "Action of a serum protein in coupling excitation contraction of heart papillary muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361599"}
{"pmid": "4361601", "title": "Mycobacterium fortuitum abscess related to surgery, malignancy, and a tight girdle.", "content": "Mycobacterium fortuitum abscess related to surgery, malignancy, and a tight girdle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361601"}
{"pmid": "4361603", "title": "Bronchiolar-alveolar carcinoma of the lung.", "content": "Bronchiolar-alveolar carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361603"}
{"pmid": "4361602", "title": "The treatment of ileocolitis with ACTH and prednisone: immediate and prolonged effect.", "content": "The treatment of ileocolitis with ACTH and prednisone: immediate and prolonged effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361602"}
{"pmid": "4361604", "title": "Current therapy of thyroid nodules.", "content": "Current therapy of thyroid nodules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361604"}
{"pmid": "4361605", "title": "Medullary carcinoma of the thyroid gland: use of biochemical parameters in detection and surgical management of the tumor.", "content": "Medullary carcinoma of the thyroid gland: use of biochemical parameters in detection and surgical management of the tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361605"}
{"pmid": "4361607", "title": "Surgical management of the Zollinger-Ellison syndrome.", "content": "Surgical management of the Zollinger-Ellison syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361607"}
{"pmid": "4361606", "title": "Endocrine surgery in children.", "content": "Endocrine surgery in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361606"}
{"pmid": "4361608", "title": "Surgical considerations in gynecologic endocrine disorders.", "content": "Surgical considerations in gynecologic endocrine disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361608"}
{"pmid": "4361609", "title": "Radical surgery of tumors of the thalamus, hypothalamus, and third ventricle area.", "content": "Radical surgery of tumors of the thalamus, hypothalamus, and third ventricle area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361609"}
{"pmid": "4361611", "title": "The ultrastructure of the accessory sex organs of the male rat. 3. The post-castration involuation of the coagulating gland and the seminal vesicle.", "content": "The ultrastructure of the accessory sex organs of the male rat. 3. The post-castration involuation of the coagulating gland and the seminal vesicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361611"}
{"pmid": "4361610", "title": "The ultrastructure of the accessory sex organs of the male rat. II. The post-castration involution of the ventral, lateral and the dorsal prostate.", "content": "The ultrastructure of the accessory sex organs of the male rat. II. The post-castration involution of the ventral, lateral and the dorsal prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361610"}
{"pmid": "4361612", "title": "Ultrastructure and functional aspects of the nucleus infundibularis ventralis in the green frog, Rana esculenta.", "content": "Ultrastructure and functional aspects of the nucleus infundibularis ventralis in the green frog, Rana esculenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361612"}
{"pmid": "4361614", "title": "Effect of denaturation on muscle proteins as studied by Epr.", "content": "Effect of denaturation on muscle proteins as studied by Epr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361614"}
{"pmid": "4361613", "title": "Electron microscopical studies on the structure, phagocytic properties, and peroxidatic activity of resident and exudate peritoneal macrophages in the guinea pig.", "content": "Electron microscopical studies on the structure, phagocytic properties, and peroxidatic activity of resident and exudate peritoneal macrophages in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361613"}
{"pmid": "4361616", "title": "Histoenzymic studies of the central nervous system in tri-ortho-cresyl phosphate poisoning.", "content": "Histoenzymic studies of the central nervous system in tri-ortho-cresyl phosphate poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361616"}
{"pmid": "4361619", "title": "Hydrosmotic effect of angiotensin II in the toad bladder: role of cyclic AMP.", "content": "Hydrosmotic effect of angiotensin II in the toad bladder: role of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361619"}
{"pmid": "4361620", "title": "Protein synthesis by isolated spermatozoa from cauda and caput epididymis of rat.", "content": "Protein synthesis by isolated spermatozoa from cauda and caput epididymis of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361620"}
{"pmid": "4361618", "title": "Influence of adrenocorticotropic hormone on red cell mass and body composition of the hypophysectomized rat.", "content": "Influence of adrenocorticotropic hormone on red cell mass and body composition of the hypophysectomized rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361618"}
{"pmid": "4361621", "title": "Isolation of proteins by gel filtration in 6M guanidinium chloride: application to RNA tumor viruses.", "content": "Isolation of proteins by gel filtration in 6M guanidinium chloride: application to RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361621"}
{"pmid": "4361623", "title": "The electrophoretic separation of nucleoside-5'-phosphates from nucleoside trialcohol monophosphates, and its application to the identification of 3'-end groups.", "content": "The electrophoretic separation of nucleoside-5'-phosphates from nucleoside trialcohol monophosphates, and its application to the identification of 3'-end groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361623"}
{"pmid": "4361622", "title": "Analysis of steroids in biological fluids by computer-aided gas-liquid chromatography--mass spectrometry.", "content": "Analysis of steroids in biological fluids by computer-aided gas-liquid chromatography--mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361622"}
{"pmid": "4361624", "title": "Fifty years with viruses (Christopher H. Andrewes).", "content": "Fifty years with viruses (Christopher H. Andrewes).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361624"}
{"pmid": "4361627", "title": "New isothiazole derivatives. II. Cytotoxicity and antiviral activity in tissue cultures.", "content": "New isothiazole derivatives. II. Cytotoxicity and antiviral activity in tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361627"}
{"pmid": "4361628", "title": "DNA in heterochromatin cytophotometric pattern recognition image analysis among cell nuclei in duct epithelium and in carcinoma of the human breast.", "content": "DNA in heterochromatin cytophotometric pattern recognition image analysis among cell nuclei in duct epithelium and in carcinoma of the human breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361628"}
{"pmid": "4361632", "title": "Comparison of hemodynamic responses to exercise in hypertensive patients and in healthy subjects given angiotensin.", "content": "Comparison of hemodynamic responses to exercise in hypertensive patients and in healthy subjects given angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361632"}
{"pmid": "4361633", "title": "Exogenous hormones in pregnancy.", "content": "Exogenous hormones in pregnancy. Various changes that have been observed after intrauterine exposure to exogenous hormones are presented.  Often, alterations observed after exogenous maternal hormone therapy consist of varying degrees of masculinization of the female genitalia.  The following specific drug interactions are described in some detail: 1) effects of progestational agents and androgens on female genitalia; 2) relationship of corticosteroids to the development of cleft palate; and 3) effects of synthetic estrogens (e.g., diethylstilbestrol) on the female reproductive tract.  The discussion closes with a review of the association of therapy with such drugs to the delayed appearance of clear-cell adenocarcinoma of the genital tract in young women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361633"}
{"pmid": "4361634", "title": "Gynecologic endocrine disorders in childhood and adolescence.", "content": "Gynecologic endocrine disorders in childhood and adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361634"}
{"pmid": "4361635", "title": "Multihormonal regulation of hepatic histidase during postnatal development.", "content": "Multihormonal regulation of hepatic histidase during postnatal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361635"}
{"pmid": "4361636", "title": "Cellular differentiation and isozymes of branched-chain amino acid transaminase.", "content": "Cellular differentiation and isozymes of branched-chain amino acid transaminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361636"}
{"pmid": "4361638", "title": "Control of rat liver phosphorylase, glucose-6-phosphatase and phosphoenolpyruvate carboxykinase activities by insulin and glucagon during the perinatal period.", "content": "Control of rat liver phosphorylase, glucose-6-phosphatase and phosphoenolpyruvate carboxykinase activities by insulin and glucagon during the perinatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361638"}
{"pmid": "4361637", "title": "Development of disaccharidase and phosphatase activities in the intestine and liver.", "content": "Development of disaccharidase and phosphatase activities in the intestine and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361637"}
{"pmid": "4361639", "title": "The regulation of liver development by birth.", "content": "The regulation of liver development by birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361639"}
{"pmid": "4361640", "title": "Nucleotide supply of the developing animal: role of the so-called 'salvage pathways'.", "content": "Nucleotide supply of the developing animal: role of the so-called 'salvage pathways'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361640"}
{"pmid": "4361641", "title": "Development of intestinal function in mammals.", "content": "Development of intestinal function in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361641"}
{"pmid": "4361642", "title": "The developmental formation of enzymes involved in glycogen metabolism.", "content": "The developmental formation of enzymes involved in glycogen metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361642"}
{"pmid": "4361644", "title": "The effects of bases and nucleosides on the intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.", "content": "The effects of bases and nucleosides on the intracellular contents of nucleotides and 5-phosphoribosyl 1-pyrophosphate in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361644"}
{"pmid": "4361643", "title": "The regulation of phosphoenolpyruvate carboxykinase in fetal rat liver.", "content": "The regulation of phosphoenolpyruvate carboxykinase in fetal rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361643"}
{"pmid": "4361645", "title": "A sequence of 54 nucleotides from the A-protein cistron of coliphage-R17 RNA.", "content": "A sequence of 54 nucleotides from the A-protein cistron of coliphage-R17 RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361645"}
{"pmid": "4361646", "title": "Studies with analogues of nicotinamide adenine dinucleotide.", "content": "Studies with analogues of nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361646"}
{"pmid": "4361648", "title": "Early chromosome changes in diploid Chinese hamster cells after infection with Simian virus 40.", "content": "Early chromosome changes in diploid Chinese hamster cells after infection with Simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361648"}
{"pmid": "4361647", "title": "Hydrolysis of the cyclic 3':5'-monophosphates of adenosine and guanosine by rat pancreas.", "content": "Hydrolysis of the cyclic 3':5'-monophosphates of adenosine and guanosine by rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361647"}
{"pmid": "4361649", "title": "Kinetics of the anti-tumor delayed hypersensitivity response in mice with progressively growing tumors: stimulation followed by specific suppression.", "content": "Kinetics of the anti-tumor delayed hypersensitivity response in mice with progressively growing tumors: stimulation followed by specific suppression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361649"}
{"pmid": "4361650", "title": "Properties of flat variants of murine sarcoma virus transformed non-producer cells isolated after high-temperature passage.", "content": "Properties of flat variants of murine sarcoma virus transformed non-producer cells isolated after high-temperature passage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361650"}
{"pmid": "4361653", "title": "Syndactyly. A review of the literature.", "content": "Syndactyly. A review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361653"}
{"pmid": "4361651", "title": "Differences in the surface mobility between normal and SV40-, polyoma- and adenovirus-transformed hamster cells.", "content": "Differences in the surface mobility between normal and SV40-, polyoma- and adenovirus-transformed hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361651"}
{"pmid": "4361652", "title": "Kinetics of uptake of 2-deoxy-D-glucose and 2-aminoisobutyric acid in chemically transformed cells.", "content": "Kinetics of uptake of 2-deoxy-D-glucose and 2-aminoisobutyric acid in chemically transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361652"}
{"pmid": "4361654", "title": "Proteolipids. VI. The dual role of phospholipid in cytochrome oxidase reaction.", "content": "Proteolipids. VI. The dual role of phospholipid in cytochrome oxidase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361654"}
{"pmid": "4361655", "title": "Spin-labelling studies of fragmented sarcoplasmic reticulum.", "content": "Spin-labelling studies of fragmented sarcoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361655"}
{"pmid": "4361659", "title": "Functional anion binding sites in dogfish M4 lactate dehydrogenase.", "content": "Functional anion binding sites in dogfish M4 lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361659"}
{"pmid": "4361658", "title": "Vinblastine in the treatment of carcinoma of liver.", "content": "Vinblastine in the treatment of carcinoma of liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361658"}
{"pmid": "4361660", "title": "Fine structure of the axon collaterals of Huber in frog spinal ganglia.", "content": "Fine structure of the axon collaterals of Huber in frog spinal ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361660"}
{"pmid": "4361661", "title": "Hypermyoinositolemic polyneuropathy in rats. A possible mechanism for uremic polyneuropathy.", "content": "Hypermyoinositolemic polyneuropathy in rats. A possible mechanism for uremic polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361661"}
{"pmid": "4361662", "title": "Multiple system atrophies. A neuropathological and neurochemical study.", "content": "Multiple system atrophies. A neuropathological and neurochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361662"}
{"pmid": "4361663", "title": "Somatosensory evoked responses to mechanical stimulation in normal subjects and in patients with neurological disorders.", "content": "Somatosensory evoked responses to mechanical stimulation in normal subjects and in patients with neurological disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361663"}
{"pmid": "4361656", "title": "The role of adenosine 3',5'-cyclic monophosphate in the regulation of mammalian cell division.", "content": "The role of adenosine 3',5'-cyclic monophosphate in the regulation of mammalian cell division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361656"}
{"pmid": "4361664", "title": "Paralysis periodica paramyotonica. A clinical and neurophysiological study.", "content": "Paralysis periodica paramyotonica. A clinical and neurophysiological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361664"}
{"pmid": "4361665", "title": "Concentrically laminated membranous inclusions in myofibres of Dyggve-Melchior-Clausen syndrome.", "content": "Concentrically laminated membranous inclusions in myofibres of Dyggve-Melchior-Clausen syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361665"}
{"pmid": "4361667", "title": "Effects of the microbial environment on drug resistance.", "content": "Effects of the microbial environment on drug resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361667"}
{"pmid": "4361666", "title": "Polyneuropathy in Waldenström's macroglobulinaemia.", "content": "Polyneuropathy in Waldenström's macroglobulinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361666"}
{"pmid": "4361670", "title": "New roles for ascorbic acid.", "content": "New roles for ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361670"}
{"pmid": "4361672", "title": "D-glyceraldehyde-3-phosphate dehydrogenase: three-dimensional structure and evolutionary significance.", "content": "D-glyceraldehyde-3-phosphate dehydrogenase: three-dimensional structure and evolutionary significance. A 3.0-A resolution electron density map of lobster glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) was computed. The essentially single isomorphous replacement map was very substantially improved by averaging subunits. NAD binds in an open conformation at sites close to subunit interfaces. The coenzyme binding portion of the enzyme has almost the same fold as the corresponding portion of lactate dehydrogenase (EC 1.1.1.27). The presence of this structure in the five enzymes, analyzed so far, that use nucleotide coenzymes might indicate a fundamental primordial structural element.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361672"}
{"pmid": "4361674", "title": "Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts.", "content": "Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts. A relatively simple but stringent technique was developed to detect the integration of virus-specific DNA into the genomes of higher organisms. In both permissive (duck) and nonpermissive (mammalian) cells which normally contain no nucleotide sequences specific for Rous sarcoma virus, transformation by the virus results in the appearance of DNA specific for Rous sarcoma virus covalently integrated into strands of host-cell DNA containing reiterated sequences. Early after infection of mouse or duck cells by Rous sarcoma virus, unintegrated DNA specific for the virus can be demonstrated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361674"}
{"pmid": "4361673", "title": "Programming of cells for death under experimental conditions: relevance to the tumor problem.", "content": "Programming of cells for death under experimental conditions: relevance to the tumor problem. An attempt was made in this study to determine more precisely the nature of the factors that are involved in the programming of cells for a form of terminal cellular differentiation that results in death. These studies demonstrated that both the cytokinesins, which are potent inhibitors of plant and animal adenosine 3':5'-cyclic monophosphate phosphodiesterases, and 8-bromoadenosine 3':5'-cyclic monophosphate, which is a stable, biologically active form of adenosine 3':5'-cyclic monophosphate, are highly effective in encouraging differentiation of parenchyma cells into tracheary elements with accompanying death. Since adenosine 3':5'-cyclic monophosphate and theophylline when used together were also effective, the results reported here suggest that adenosine 3':5'-cyclic monophosphate is somehow importantly involved in the conversion of parenchyma cells into tracheary elements in this system. The possible significance to the tumor problem generally of the programming of cells for terminal differentiation, with or without resulting death, is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361673"}
{"pmid": "4361675", "title": "A mammalian cell mutant with a temperature-sensitive leucyl-transfer RNA synthetase.", "content": "A mammalian cell mutant with a temperature-sensitive leucyl-transfer RNA synthetase. A cell mutant of the Chinese hamster ovary line, which is temperature sensitive for protein synthesis, is specifically defective in vivo in its ability to charge tRNA with leucine. Cytoplasmic extracts exhibited temperature-sensitive leucyl-tRNA synthetase activity. It is, therefore, highly likely that the mutant has a structural alteration in leucyl-tRNA synthetase. The low leakiness and low reversion rate of this mutant, combined with the specificity of the defect in its protein-synthesizing machinery, make it an appealing tool for investigating regulatory mechanisms in animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361675"}
{"pmid": "4361677", "title": "Charge transfer between amine and carbonyl.", "content": "Charge transfer between amine and carbonyl. The transfer of a whole electron in the ground state can be demonstrated by the interaction of p-phenylenediamine and glyoxal, which leads to the formation of free radicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361677"}
{"pmid": "4361676", "title": "Adenosine-mediated elevation of cyclic 3':5'-adenosine monophosphate concentrations in cultured mouse neuroblastoma cells.", "content": "Adenosine-mediated elevation of cyclic 3':5'-adenosine monophosphate concentrations in cultured mouse neuroblastoma cells. Adenosine causes an increase in the concentration of cyclic AMP in mouse neuroblastoma cells. The amount of increase observed in intracellular cyclic AMP levels due to exogenous adenosine depends greatly on the concentration of a specific cyclic AMP phosphodiesterase inhibitor, 4-(-3-butoxy-4-methoxybenzyl)-2-imidazolidinone. Unstimulated concentrations of cyclic AMP were 29-40 pmol/mg of protein, and concentrations after addition of 0.2 mM adenosine were usually twice as high. The presence of 0.7 mM inhibitor along with 0.2 mM adenosine caused an increase in cyclic AMP levels up to 1000-2000 pmol/mg of protein. In the presence of 0.7 mM inhibitor, 2 muM adenosine gives a half-maximal cyclic AMP elevation. Theophylline blocked the elevation of cyclic AMP concentrations caused by exogenous adenosine. The data show that the cyclic AMP system of mouse neuroblastoma has the necessary receptor components to respond positively to exogenous adenosine. The results presented support a direct effect of adenosine, mediated through its control of intracellular levels, on neuronal elements of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361676"}
{"pmid": "4361678", "title": "Heme proteins: quantum yield determined by the pulse method.", "content": "Heme proteins: quantum yield determined by the pulse method. We report results of the application of the \"pulse method\" to the study of photodissociation of various ligands from several heme proteins. By use of this technique, which allows the determination of the quantum yield of photodissociation accurately and rapidly, several ligands (CO, O(2), isocyanides) have been investigated for sperm-whale myoglobin and trout hemoglobin I. In agreement with previous results, the new data lead to the conclusion that no simple relationship exists between the quantum yield and the affinity constant in the ground state. For trout hemoglobin I, the experiments were extended to measure the quantum yield of the CO photodissociation as a function of the initial degree of saturation, from fully saturated down to the initial values of about 1.5%. The results yield additional information to that obtained by the \"steady-state\" method, and in particular exclude the idea that the photochemical yield is in any way dependent on the fractional saturation of the molecule with carbon monoxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361678"}
{"pmid": "4361679", "title": "Alteration of cell-surface proteins by viral transformation and by proteolysis.", "content": "Alteration of cell-surface proteins by viral transformation and by proteolysis. Putative cell-surface proteins of tissue-culture cells were identified by lactoperoxidase-catalyzed iodination, a technique that attaches label only to proteins outside the cell membrane. Evidence is presented that these proteins are cell derived, not contaminating serum proteins. On \"normal\" cells, which exhibit density dependence of growth, one protein of high molecular weight was particularly readily iodinated. This protein was easily removed by mild proteolytic digestion, and, in virus-transformed cells, was either absent or unavailable for iodination. The possible relevance of these observations to the control of growth in cell culture is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361679"}
{"pmid": "4361680", "title": "Biological and biochemical evidence for an interaction between Marek's disease herpesvirus and avian leukosis virus in vivo.", "content": "Biological and biochemical evidence for an interaction between Marek's disease herpesvirus and avian leukosis virus in vivo. The DNA-containing Epstein-Barr herpesvirus has been implicated in the etiology of Burkitt's lymphoma, a malignant tumor of children in Africa. Recently, however, particles possessing four biochemical characteristics of RNA tumor viruses have also been identified in these tumors. The fact that both types of viruses are found suggests that an interaction between them may be playing a role in the etiology of Burkitt's lymphoma. To explore this possibility with a defined animal model, experiments were performed with the avian Marek's disease, a malignant lymphoproliferative disease associated with a herpesvirus. Controlled contact studies demonstrated that tumorigenesis in a line of isolator-derived, barrier-sustained, specific pathogen-free chickens requires exposure to both the Marek's disease herpesvirus and an avian leukosis virus, Rous-associated virus, type 2. Exposure to either agent alone did not result in tumors. Molecular hybridization experiments to cytoplasmic RNA from similarly contact-exposed conventional Cornell S-line chickens provided further evidence for the occurrence of an interaction between Marek's disease herpesvirus and the avian leukosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361680"}
{"pmid": "4361681", "title": "Pressure effect on the membrane action of a nerve-blocking spin label.", "content": "Pressure effect on the membrane action of a nerve-blocking spin label. A reversible nerve-blocking spin label, 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) was used to study the nature of anesthetic-binding sites in nerve membranes as a function of pressure. The nerve-blocking effect of TEMPO is enhanced under pressure. At atmospheric pressure, TEMPO blocks nerve conduction by solubilizing in the apolar region of the nerve membrane. However, the nerve-conduction-block by TEMPO at 150 atm of helium was related to the binding of TEMPO to a pressure-induced high-affinity polar site in the nerve membrane. The new TEMPO-binding site could not be detected in lipid model membranes and, thus, the involvement of membrane protein in the new site was inferred. Pressure may induce a nerve membrane conformation change in the presence of TEMPO. The observation that under different pressure, a single anesthetic, i.e., TEMPO, was capable of blocking nerve conduction by binding to two different sites within the nerve membrane, supports the view that there are multiple anesthetic receptor sites, which differ in chemical composition and location within the nerve membrane. These sites, when occupied by different classes of anesthetics, produce the general phenomenon of nerve-conduction block. The enhancement of nerve-conduction block by pressure may be due to the increased concentration of TEMPO in the new site in the nerve membrane under pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361681"}
{"pmid": "4361683", "title": "Malignant transformation of BHK21 clone 13 cells by BK virus--a human papovavirus.", "content": "Malignant transformation of BHK21 clone 13 cells by BK virus--a human papovavirus. BK virus, a widespread human papovavirus, is shown to cause malignant transformation of BHK(21) clone 13 cells. The transformed cells grow as tumors upon inoculation in adult hamsters. The question of the possible role of this virus in human neoplasia is raised.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361683"}
{"pmid": "4361684", "title": "Regulation of glucose synthesis in hormone-sensitive isolated rat hepatocytes.", "content": "Regulation of glucose synthesis in hormone-sensitive isolated rat hepatocytes. A simplified procedure was developed for isolation of intact, hormone-sensitive liver cells in a high and reproducible yield. These cells produce glucose from various precursors at rates comparable to those achieved in isolated perfused liver. Glucagon enhanced glucose synthesis from pyruvate, dihydroxyacetone, fructose, or xylitol more effectively at low than at high substrate concentration. At high pyruvate concentrations (>2 mM), glucagon or adenosine 3':5'-cyclic monophosphate (0.1 mM) exerts a curious inhibition of gluconeogenesis that can be reverted to stimulation on addition of ethanol. It is suggested that glucagon and cyclic AMP inhibit pyruvate dehydrogenase and thus limit the supply of reducing equivalents needed for glucose formation. Supporting evidence for hormonal control of pyruvate dehydrogenase in isolated liver cells is provided by the fact that glucagon decreases and insulin increases decarboxylation of [1-(14)C]pyruvate. Calcium salts (1.3 mM) enhance glucose formation from pyruvate but greatly enhance the inhibition exerted by the divalent cationophore, A23187. Inhibition by glucagon of glucose synthesis from pyruvate is additive with the effects of A23187 + Ca(++). However, with dihydroxyacetone as substrate, glucagon partially reverses the inhibition exerted by A23187 + Ca(++). The results are consistent with glucagon effecting an inhibition of pyruvate dehydrogenase and a stimulation of hexosediphosphatase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361684"}
{"pmid": "4361685", "title": "Herpes simplex and herpes genitalis viruses in etiology of some human cancers.", "content": "Herpes simplex and herpes genitalis viruses in etiology of some human cancers. The results of complement fixation tests on 202 sera from people without cancer and from patients with cancer in 29 different areas of the body indicated that only those with nine varieties of advanced cancer (lip, mouth, oropharynx, nasopharynx, kidney, urinary bladder, prostate, cervix uteri, and vulva-all of 56 tested) gave positive specific reactions with nonvirion antigens induced by the DNA herpes simplex (HSV 1) and herpes genitalis (HSV 2) viruses. None of 57 people without cancer (including 10 with current and 18 with recurrent HSV 1 or HSV 2 infections), none of 81 patients with 20 other varieties of advanced cancer (gum, tongue, tonsil, salivary gland, accessory sinus, epiglottis, lung-bronchus, stomach, colon, breast, corpus uteri, ovary, testis, liver, thyroid, Wilms' embryonal kidney, melanoma, Hodgkin's disease, acute lymphocytic leukemia, and acute myelocytic leukemia), and none of four women with early malignant changes in the cervix uteri gave positive results. The seven patients with advanced cancer of the lip or oropharynx gave positive reactions with HSV 1 but not with HSV 2 nonvirion antigens (compatible with involvement of only HSV 1), all of the 13 women with advanced cancer of the cervix uteri and the one woman with advanced cancer of the vulva gave positive reactions with both HSV 1 and HSV 2 nonvirion antigens (compatible with involvement of only HSV 2), while among the 35 other positive patients only two (one with cancer of the kidney and one with cancer of the bladder) reacted with HSV 1 and not at all with HSV 2 nonvirion antigens. Positive sera failed to react with cells harvested at different times after high-multiplicity infection with the DNA vaccinia virus. Massive absorption of positive sera with trypsinized, uninfected human embryonic kidney cells failed to remove, or lower the titer of, the HSV 1 and HSV 2 nonvirion antibodies. All of these data taken together are interpreted as indicating that HSV 1 and HSV 2 play an etiologic role in certain human cancers, because they provide the kind of evidence by which virus-free experimental cancers can be proved to have been originally induced by such DNA viruses as polyoma, Simian Virus 40, or certain types of adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361685"}
{"pmid": "4361686", "title": "Separate intramolecular pathways for reduction and oxidation of cytochrome c in electron transport chain reactions.", "content": "Separate intramolecular pathways for reduction and oxidation of cytochrome c in electron transport chain reactions. The monoiodotyrosine 74, formyltryptophan 59, mononitrotyrosine 67, and carboxymethylmethionine 80 derivatives of horse cytochrome c are defective in their ability to accept electrons from the succinate-cytochrome c reductase system, while their reactions with purified cytochrome c oxidase are essentially those of the native protein. The 4-nitrobenzo-2-oxa-1,3-diazole derivative of lysine 13 of horse cytochrome c and the bis-phenylglyoxal derivative of arginine 13 of Candida krusei cytochrome c have the opposite properties, in that they are readily reduced by the succinate-cytochrome c reductase (EC 1.3.99.1) system but are defective in their capability of transferring electrons to cytochrome c oxidase (EC 1.9.3.1). We conclude that electrons from mitochondrial cytochrome c reductase are transmitted to ferricytochrome c by a different pathway than electrons from ferrocytochrome c to cytochrome c oxidase. The present results are compatible with the concept that the mechanism of reduction involves an aromatic ring channel comprising residues 74, 59, 67, and 80, leading from the \"left back\" part of the protein to the heme iron. On the other hand, since residue 13 is immediately above the edge of the heme that is at the \"front surface\" of the molecule, we suggest that the electron leaves ferrocytochrome c to cytochrome c oxidase by way of the edge of pyrrole ring II or the adjacent surface-located sulfur of cysteinyl residue 17, which is thioether bonded to the heme. On this basis, the sites of electron entry and exit in cytochrome c would appear to be some 110 degrees of arc away from each other along the surface of the protein, explaining several previously observed phenomena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361686"}
{"pmid": "4361682", "title": "Plasma membranes from cultured muscle cells: isolation procedure and separation of putative plasma-membrane marker enzymes.", "content": "Plasma membranes from cultured muscle cells: isolation procedure and separation of putative plasma-membrane marker enzymes. Partially purified plasma membranes were obtained from chick-embryo muscle cells grown in tissue culture. The purification procedure involved homogenization in buffered isotonic sucrose followed by differential and sucrose density gradient centrifugations. The activities of five plasma-membrane markers, as well as microsomal and mitochondrial markers, were followed throughout the purification. When cultures were labeled with [(125)I]alpha-bungarotoxin, which binds to the surface of cultured muscle cells, the distributions of bound alpha-bungarotoxin and Na(+),K(+)-ATPase (EC 3.6.1.3) activity were nearly identical. The activities of these two plasma-membrane markers were maximal in the upper two fractions of the sucrose density gradient and were purified 5- to 7-fold with respect to total particulate protein. These fractions contained 20-30% of the Na(+),K(+)-ATPase activity and bound alpha-bungarotoxin, 4% of the microsomal marker TPNH-dependent cytochrome c reductase, 0.2% of the mitochondrial marker succinate-dependent cytochrome c reductase, 2.7% of the cellular RNA, and 0.02% of the DNA. The activity of the commonly used plasma-membrane marker, 5'-nucleotidase (EC 3.1.3.5), was low in the upper two sucrose gradient fractions and was maximal in a more dense fraction. The distributions of the other two plasma-membrane markers, leucyl beta-naphthylamidase and phosphodiesterase I, were intermediate between Na(+),K(+)-ATPase and 5'-nucleotidase. The distributions of all markers were similar in preparations from cultures containing mononucleated myogenic cells, multinucleated myotubes, fibroblasts, or all three cell types. Modification of the procedure to include homogenization in the absence of sucrose resulted in a 3.4-fold purification of the membranes containing 5'-nucleotidase, which were shifted to a lower density.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361682"}
{"pmid": "4361687", "title": "DNA of Epstein-Barr virus detected in tissue of Burkitt's lymphoma and nasopharyngeal carcinoma.", "content": "DNA of Epstein-Barr virus detected in tissue of Burkitt's lymphoma and nasopharyngeal carcinoma. The association of Epstein-Barr virus (EBV) DNA with African tumors was examined by the method of hybridization with complementary RNA. 22 out of 23 biopsies of Burkitt's lymphoma and 18 out of 23 biopsies of nasopharyngeal carcinoma were found to contain EBV DNA. The number of EBV genome equivalents per cell ranged from four to 113. Five out of 24 other African tumors, two adenocarcinomas, and one each of melanoma, reticulum cell sarcoma, and carcinoma of the antrum, also contained EBV DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361687"}
{"pmid": "4361693", "title": "A four-year clinical and serologic study of the use of inactivated parainfluenza-3 virus vaccines and Pasteurella sp. bacterins in beef calves.", "content": "A four-year clinical and serologic study of the use of inactivated parainfluenza-3 virus vaccines and Pasteurella sp. bacterins in beef calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361693"}
{"pmid": "4361697", "title": "On the nature of frequency dependence of the evoked potentials in the cat's auditory cortex.", "content": "On the nature of frequency dependence of the evoked potentials in the cat's auditory cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361697"}
{"pmid": "4361696", "title": "Effect of conformational changes on the enzymatic inactivation of pig and rabbit skeletal muscle phosphorylase-a.", "content": "Effect of conformational changes on the enzymatic inactivation of pig and rabbit skeletal muscle phosphorylase-a.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361696"}
{"pmid": "4361700", "title": "Plasma vitamin E and cholesterol relationship in Western Canadian Indians.", "content": "Plasma vitamin E and cholesterol relationship in Western Canadian Indians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361700"}
{"pmid": "4361699", "title": "Relationship of ethanol to choline metabolism in the liver: a review.", "content": "Relationship of ethanol to choline metabolism in the liver: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361699"}
{"pmid": "4361703", "title": "Letter: Herpesvirus type 2 infection and cervical carcinoma.", "content": "Letter: Herpesvirus type 2 infection and cervical carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361703"}
{"pmid": "4361701", "title": "Guanine nucleotides and their significance in biochemical processes.", "content": "Guanine nucleotides and their significance in biochemical processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361701"}
{"pmid": "4361702", "title": "In vitro viral studies of cells grown from human amniotic fluid samples.", "content": "In vitro viral studies of cells grown from human amniotic fluid samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361702"}
{"pmid": "4361704", "title": "Height, weight, and lines of arrested growth in young Guatemalan children.", "content": "Height, weight, and lines of arrested growth in young Guatemalan children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361704"}
{"pmid": "4361705", "title": "Amebic liver abscess following metronidazole therapy for amebic colitis.", "content": "Amebic liver abscess following metronidazole therapy for amebic colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361705"}
{"pmid": "4361706", "title": "Synergistic interaction of two agents in mice: Japanese B encephalitis virus and Trichinella spiralis.", "content": "Synergistic interaction of two agents in mice: Japanese B encephalitis virus and Trichinella spiralis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361706"}
{"pmid": "4361707", "title": "Needle-like cytoplasmic inclusions in the liver in prophyria cutanea tarda.", "content": "Needle-like cytoplasmic inclusions in the liver in prophyria cutanea tarda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361707"}
{"pmid": "4361710", "title": "A proposal linking atherogenesis to the interaction of endothelial lipoprotein lipase with triglyceride-rich lipoproteins.", "content": "A proposal linking atherogenesis to the interaction of endothelial lipoprotein lipase with triglyceride-rich lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361710"}
{"pmid": "4361711", "title": "Impaired left ventricular function in alcoholic cirrhosis with ascites. Ineffectiveness of ouabain.", "content": "Impaired left ventricular function in alcoholic cirrhosis with ascites. Ineffectiveness of ouabain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361711"}
{"pmid": "4361713", "title": "Chromatin-bound kinase activity and phosphorylation of chromatin non-histone proteins during early kidney regeneration after folic acid.", "content": "Chromatin-bound kinase activity and phosphorylation of chromatin non-histone proteins during early kidney regeneration after folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361713"}
{"pmid": "4361714", "title": "Adhesion of culture cells to their substratum.", "content": "Adhesion of culture cells to their substratum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361714"}
{"pmid": "4361715", "title": "An unusual cytoplasmic iron-binding material that disappears from diploid cells placed in culture.", "content": "An unusual cytoplasmic iron-binding material that disappears from diploid cells placed in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361715"}
{"pmid": "4361717", "title": "Inhibition by cyclic AMP dibutyryl cyclic AMP of aggregation of embryonic quail liver cells in culture.", "content": "Inhibition by cyclic AMP dibutyryl cyclic AMP of aggregation of embryonic quail liver cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361717"}
{"pmid": "4361716", "title": "Intracellular antigen migration in interspecific myoblast heterokaryons.", "content": "Intracellular antigen migration in interspecific myoblast heterokaryons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361716"}
{"pmid": "4361719", "title": "Stimulation of 2-deoxyglucose uptake in growth-inhibited BALB-C 3T3 and revertant SV40-transformed 3T3 cells.", "content": "Stimulation of 2-deoxyglucose uptake in growth-inhibited BALB-C 3T3 and revertant SV40-transformed 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361719"}
{"pmid": "4361718", "title": "Subfractionation and properties of rat kidney cortex microsomal fraction.", "content": "Subfractionation and properties of rat kidney cortex microsomal fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361718"}
{"pmid": "4361720", "title": "Estrogen sensitive cell lines: establishment and characterization of new cell lines from estrogen-induced rat pituitary tumors.", "content": "Estrogen sensitive cell lines: establishment and characterization of new cell lines from estrogen-induced rat pituitary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361720"}
{"pmid": "4361722", "title": "Heterogeneity of the cell population of the cellular slime mold Dictyostelium discoideum before aggregation, and its relation to the subsequent locations of the cells.", "content": "Heterogeneity of the cell population of the cellular slime mold Dictyostelium discoideum before aggregation, and its relation to the subsequent locations of the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361722"}
{"pmid": "4361721", "title": "The relationship between concentration of prostaglandin E and rates of cell replication.", "content": "The relationship between concentration of prostaglandin E and rates of cell replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361721"}
{"pmid": "4361723", "title": "Myocardial lesions in the offspring of female rats fed a copper deficient diet.", "content": "Myocardial lesions in the offspring of female rats fed a copper deficient diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361723"}
{"pmid": "4361725", "title": "Stimulating effect of crystalline cholesterol on spermiogenesis and oxidative activity in the senile rat testicle.", "content": "Stimulating effect of crystalline cholesterol on spermiogenesis and oxidative activity in the senile rat testicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361725"}
{"pmid": "4361724", "title": "Effect of suramin in doses blocking trypan blue endocytosis on some enzymes in mouse liver.", "content": "Effect of suramin in doses blocking trypan blue endocytosis on some enzymes in mouse liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361724"}
{"pmid": "4361726", "title": "Technique of electron spin resonance investigations in the x-ray field.", "content": "Technique of electron spin resonance investigations in the x-ray field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361726"}
{"pmid": "4361727", "title": "Local antibody response to experimental poliovirus infection in the central nervous system of rhesus monkeys.", "content": "Local antibody response to experimental poliovirus infection in the central nervous system of rhesus monkeys. By employing the techniques of immunofluorescence and radioimmunodiffusion using (32)P-labeled poliovirus as the antigen, the immunoglobulin response to poliovirus in serum, nasopharynx, spinal fluid, and in different segments of the central nervous system (CNS) was studied after intramuscular, oral, intranasal, and intrathalamic administration of inactivated (Salk), live attenuated (Sabin), or live virulent (Mahoney) type I poliovirus. Spinal fluid gammaG antibody was detected after immunization with Sabin or Mahoney virus and intramuscular administration of Salk vaccine. The response in the CNS was characterized by the appearance of gammaG antibody after oral or intrathalamic administration of Mahoney virus and rarely after intrathalamic inoculation of Sabin vaccine. The antibody activity in CNS was limited to the areas of poliovirus replication. Intrathalamic immunization with Mahoney virus resulted in local gammaG antibody production in the CNS in the absence of any detectable response in serum. Discrete foci of gammaG-containing cells were observed in those areas of CNS which contained poliovirus antibody. No immunoglobulin-containing cells or poliovirus antibody was seen in the CNS of monkeys immunized with intramuscularly or orally administered Sabin or Salk vaccine and in sham-immunized control monkeys. It is suggested that the CNS, when stimulated locally with a potent replicating viral antigen, may manifest a specific local antibody response, which is independent of the response in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361727"}
{"pmid": "4361728", "title": "California arbovirus (La Crosse) infections. II. Precipitin antibody tests for the diagnosis of California encephalitis.", "content": "California arbovirus (La Crosse) infections. II. Precipitin antibody tests for the diagnosis of California encephalitis. Precipitin antibodies to California group arboviruses were studied by double agar gel immunodiffusion (ID) and counterimmunoelectrophoresis (CEP). Forty children with California encephalitis (CE), 12 patients with other forms of meningoencephalitis, and 120 residents of endemic CE areas were tested. Precipitin antibodies were detected only in the 40 patients with CE, whereas hemagglutination-inhibiting, neutralizing, and complement-fixing antibodies were also found in persons without a history of CE. Precipitin antibodies did not persist for more than a year, in contrast to the other three antibodies which may be detected for 2 or more years. Of the children with CE, 36% had precipitin antibodies in their acute sera by CEP and 44% by ID. Precipitin responses were subtype-specific, and the patients reacted most strongly with La Crosse virus. The results indicated that precipitin techniques would be useful for the early detection of CE in some patients and that the presence of precipitin antibodies in a patient with acute central nervous system infection is strongly suggestive of CE. In addition, precipitin tests can be used to distinguish the California subtype responsible for CE in a given area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361728"}
{"pmid": "4361730", "title": "Continuous cyclic hormonal therapy.", "content": "Continuous cyclic hormonal therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361730"}
{"pmid": "4361729", "title": "Role of interferon in murine lactic dehydrogenase virus infection, in vivo and in vitro.", "content": "Role of interferon in murine lactic dehydrogenase virus infection, in vivo and in vitro. The induction of interferon (IF) by lactic dehydrogenase virus (LDV) and the action of exogenous IF on LDV multiplication have been studied in vivo and in vitro. In vivo the induction of serum IF by LDV was shown to correspond with the virus challenge dose. In vitro LDV-infected macrophages did not produce detectable IF. As to the action of IF in vivo, the prophylactic or therapeutic administration of IF to mice reduced the LDV serum titers only temporarily. In vitro, (i) the sensitivity of LDV to IF in macrophage culture was 30 times less than that of vesicular stomatitis virus, and 5 times less than that of Sendai virus, and (ii) prolonged exposure of LDV-infected macrophages to high IF concentrations did not cure the chronic infection, but only decreased the virus titer. The probable role of IF in the establishment of the early phase of a persistent but reduced viremia in mice is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361729"}
{"pmid": "4361731", "title": "The distribution of transfer ribonucleic acid in rabbit reticulocytes. Levels of aminoacylation and ribosomal attachment during hemoglobin synthesis.", "content": "The distribution of transfer ribonucleic acid in rabbit reticulocytes. Levels of aminoacylation and ribosomal attachment during hemoglobin synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361731"}
{"pmid": "4361733", "title": "Characterization of a proposed oxytocin receptor in the uterus of the rat and sow.", "content": "Characterization of a proposed oxytocin receptor in the uterus of the rat and sow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361733"}
{"pmid": "4361732", "title": "The mechanism of end product inhibition of serine biosynthesis. IV. Subunit structure of phosphoglycerate dehydrogenase and steady state kinetic studies of phosphoglycerate oxidation.", "content": "The mechanism of end product inhibition of serine biosynthesis. IV. Subunit structure of phosphoglycerate dehydrogenase and steady state kinetic studies of phosphoglycerate oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361732"}
{"pmid": "4361735", "title": "A new apoprotein of human plasma very low density lipoproteins.", "content": "A new apoprotein of human plasma very low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361735"}
{"pmid": "4361734", "title": "Rat brain tubulin and protein kinase activity.", "content": "Rat brain tubulin and protein kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361734"}
{"pmid": "4361736", "title": "The involvement of serine and carboxyl groups in the activity of bovine pancreatic deoxyribonuclease A.", "content": "The involvement of serine and carboxyl groups in the activity of bovine pancreatic deoxyribonuclease A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361736"}
{"pmid": "4361737", "title": "Chicken liver phosphofructokinase. 3. Kinetics and allosteric properties.", "content": "Chicken liver phosphofructokinase. 3. Kinetics and allosteric properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361737"}
{"pmid": "4361738", "title": "Regulation of mitochondrial alpha-ketoglutarate metabolism by product inhibition at alpha-ketoglutarate dehydrogenase.", "content": "Regulation of mitochondrial alpha-ketoglutarate metabolism by product inhibition at alpha-ketoglutarate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361738"}
{"pmid": "4361739", "title": "A mammalian endonuclease specific for apurinic sites in double-stranded deoxyribonucleic acid. II. Further studies on the substrate specificity.", "content": "A mammalian endonuclease specific for apurinic sites in double-stranded deoxyribonucleic acid. II. Further studies on the substrate specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361739"}
{"pmid": "4361740", "title": "Membrane glycopeptides from subcellular fractions of control and virus-transformed cells.", "content": "Membrane glycopeptides from subcellular fractions of control and virus-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361740"}
{"pmid": "4361742", "title": "The cytoplasmic estradiol receptors of bovine uterus. Their occurrence, interconversion, and binding properties.", "content": "The cytoplasmic estradiol receptors of bovine uterus. Their occurrence, interconversion, and binding properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361742"}
{"pmid": "4361743", "title": "Synthesis of virus-capsid antigen (VCA) enhanced by ultraviolet irradiation of a lymphoblastoid cell line carrying Epstein-Barr virus.", "content": "Synthesis of virus-capsid antigen (VCA) enhanced by ultraviolet irradiation of a lymphoblastoid cell line carrying Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361743"}
{"pmid": "4361741", "title": "Stimulation of hydrolysis of phosphatidic acid by cholinergic agents in guinea pig synaptosomes.", "content": "Stimulation of hydrolysis of phosphatidic acid by cholinergic agents in guinea pig synaptosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361741"}
{"pmid": "4361744", "title": "Elevated inorganic pyrophosphate concentrations in synovial fluids in osteoarthritis and pseudogout.", "content": "Elevated inorganic pyrophosphate concentrations in synovial fluids in osteoarthritis and pseudogout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361744"}
{"pmid": "4361746", "title": "The effect of cyanate upon 2,3-diphosphoglyceric acid metabolism.", "content": "The effect of cyanate upon 2,3-diphosphoglyceric acid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361746"}
{"pmid": "4361745", "title": "Oxidative energy metabolism in the skeletal muscle: biochemical and ultrastructural evidence for adaptive changes.", "content": "Oxidative energy metabolism in the skeletal muscle: biochemical and ultrastructural evidence for adaptive changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361745"}
{"pmid": "4361747", "title": "Differential methylation of mitochondrial and nuclear DNA in cultured mouse, hamster and virus-transformed hamster cells. In vivo and in vitro methylation.", "content": "Differential methylation of mitochondrial and nuclear DNA in cultured mouse, hamster and virus-transformed hamster cells. In vivo and in vitro methylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361747"}
{"pmid": "4361748", "title": "Half-of-the sites reactivity in the catalytic mechanism of yeast glyceraldehyde 3-phosphate dehydrogenase.", "content": "Half-of-the sites reactivity in the catalytic mechanism of yeast glyceraldehyde 3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361748"}
{"pmid": "4361750", "title": "Molecular basis of negative co-operativity in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase.", "content": "Molecular basis of negative co-operativity in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361750"}
{"pmid": "4361749", "title": "Secondary structure in heterogeneous nuclear RNA: involvement of regions from repeated DNA sites.", "content": "Secondary structure in heterogeneous nuclear RNA: involvement of regions from repeated DNA sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361749"}
{"pmid": "4361751", "title": "Letter: In vitro polyoma DNA synthesis: involvement of RNA in discontinuous chain growth.", "content": "Letter: In vitro polyoma DNA synthesis: involvement of RNA in discontinuous chain growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361751"}
{"pmid": "4361752", "title": "Accumulation of single-stranded regions in DNA and the block to replication in a human cell line alkylated with methyl methane sulfonate.", "content": "Accumulation of single-stranded regions in DNA and the block to replication in a human cell line alkylated with methyl methane sulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361752"}
{"pmid": "4361753", "title": "Dependence of the sedimentation coefficient of denatured closed circular DNA in alkali on the degree of strand interwinding. The absolute sense of supercoils.", "content": "Dependence of the sedimentation coefficient of denatured closed circular DNA in alkali on the degree of strand interwinding. The absolute sense of supercoils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361753"}
{"pmid": "4361755", "title": "Cystic meningiomas simulating astrocytomas. Report of three cases.", "content": "Cystic meningiomas simulating astrocytomas. Report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361755"}
{"pmid": "4361754", "title": "In vitro polyoma DNA synthesis: discontinuous chain growth.", "content": "In vitro polyoma DNA synthesis: discontinuous chain growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361754"}
{"pmid": "4361756", "title": "Evidence for a vasopressor substance (renin) in human fetal kidneys.", "content": "Evidence for a vasopressor substance (renin) in human fetal kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361756"}
{"pmid": "4361757", "title": "Prevention of malignant hypertension by the synthetic peptide SQ 20,881.", "content": "Prevention of malignant hypertension by the synthetic peptide SQ 20,881.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361757"}
{"pmid": "4361762", "title": "Persistent herpes simplex virus infection in rabbit trigeminal ganglia.", "content": "Persistent herpes simplex virus infection in rabbit trigeminal ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361762"}
{"pmid": "4361758", "title": "Ultrastructure of the glomerular basement membrane in long term renal allografts with transplant glomerular disease.", "content": "Ultrastructure of the glomerular basement membrane in long term renal allografts with transplant glomerular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361758"}
{"pmid": "4361763", "title": "Letter: Hyperphosphatemia and hypocalcemia in neoplastic disorders.", "content": "Letter: Hyperphosphatemia and hypocalcemia in neoplastic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361763"}
{"pmid": "4361764", "title": "Letter: Crystalline perinuclear inclusions in myoblasts from human dystrophic muscle.", "content": "Letter: Crystalline perinuclear inclusions in myoblasts from human dystrophic muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361764"}
{"pmid": "4361765", "title": "Analytical zonal centrifugation of synaptosomes and mitochondria from rat brain homogenates.", "content": "Analytical zonal centrifugation of synaptosomes and mitochondria from rat brain homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361765"}
{"pmid": "4361766", "title": "Neuroblastoma cell differentiation: a tissue culture study using time-lapse cinematography.", "content": "Neuroblastoma cell differentiation: a tissue culture study using time-lapse cinematography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361766"}
{"pmid": "4361767", "title": "Description of \"Minnesota Thermal Disks\" and normal values of cutaneous thermal discrimination in man.", "content": "Description of \"Minnesota Thermal Disks\" and normal values of cutaneous thermal discrimination in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361767"}
{"pmid": "4361770", "title": "Acute hypertension and prolonged focal cerebral ischemia.", "content": "Acute hypertension and prolonged focal cerebral ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361770"}
{"pmid": "4361771", "title": "Latent herpes simplex virus infection in human trigeminal ganglia.", "content": "Latent herpes simplex virus infection in human trigeminal ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361771"}
{"pmid": "4361772", "title": "Reactivation of herpes simplex virus in nonpermissive cells: dependence on cell fusion.", "content": "Reactivation of herpes simplex virus in nonpermissive cells: dependence on cell fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361772"}
{"pmid": "4361773", "title": "Immunoglobulin deposits in amyotrophic lateral sclerosis.", "content": "Immunoglobulin deposits in amyotrophic lateral sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361773"}
{"pmid": "4361775", "title": "Disorders of the immunoglobulin A system in hereditary sensory neuropathy.", "content": "Disorders of the immunoglobulin A system in hereditary sensory neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361775"}
{"pmid": "4361774", "title": "The uptake of 36C1 into astrocytes in tissue culture by a potassium-dependent, saturable process: implications for epilepsy and cortical edema.", "content": "The uptake of 36C1 into astrocytes in tissue culture by a potassium-dependent, saturable process: implications for epilepsy and cortical edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361774"}
{"pmid": "4361776", "title": "Affection of the vagus and sympathetic nerves in alcoholic polyneuropathy.", "content": "Affection of the vagus and sympathetic nerves in alcoholic polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361776"}
{"pmid": "4361777", "title": "A severe pansensory familial neuropathy.", "content": "A severe pansensory familial neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361777"}
{"pmid": "4361778", "title": "Peripheral nerve involvement in Tangier disease.", "content": "Peripheral nerve involvement in Tangier disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361778"}
{"pmid": "4361768", "title": "Bacterial endophthalmitis after cataract extraction. II. Incidence in 36,000 consecutive operations with special reference to preoperative topical antibiotics.", "content": "Bacterial endophthalmitis after cataract extraction. II. Incidence in 36,000 consecutive operations with special reference to preoperative topical antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361768"}
{"pmid": "4361780", "title": "Mechanism of antibiotic-induced neuromuscular block.", "content": "Mechanism of antibiotic-induced neuromuscular block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361780"}
{"pmid": "4361779", "title": "Variability of neuromuscular transmission in myasthenia gravis.", "content": "Variability of neuromuscular transmission in myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361779"}
{"pmid": "4361781", "title": "Reduced acetylcholine receptors in myasthenia gravis.", "content": "Reduced acetylcholine receptors in myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361781"}
{"pmid": "4361769", "title": "Nonauditory of effects of noise.", "content": "Nonauditory of effects of noise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361769"}
{"pmid": "4361785", "title": "Leukocytes as secretory organs of inflammation.", "content": "Leukocytes as secretory organs of inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361785"}
{"pmid": "4361787", "title": "Herpesvirus and Epstein-Barr virus antibodies and carcinoma of the intrinsic larynx.", "content": "Herpesvirus and Epstein-Barr virus antibodies and carcinoma of the intrinsic larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361787"}
{"pmid": "4361786", "title": "Hepatic cellular responses to liver cancer: abnormalities in metabolism of mitochondria isolated from human liver involved with carcinoma.", "content": "Hepatic cellular responses to liver cancer: abnormalities in metabolism of mitochondria isolated from human liver involved with carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361786"}
{"pmid": "4361789", "title": "Effect of bromocarbamide on fibroblasts in vitro: fine structural changes in mouse fibroblasts.", "content": "Effect of bromocarbamide on fibroblasts in vitro: fine structural changes in mouse fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361789"}
{"pmid": "4361790", "title": "Electron microscopy of isolated rat hepatocytes before and after treatment with phalloidin.", "content": "Electron microscopy of isolated rat hepatocytes before and after treatment with phalloidin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361790"}
{"pmid": "4361791", "title": "Necrotic changes of the rabbit adenohypophysis following orthostatic collapse.", "content": "Necrotic changes of the rabbit adenohypophysis following orthostatic collapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361791"}
{"pmid": "4361792", "title": "Studies on the mode of proliferation of rat liver cells in chronic thioacetamide intoxication.", "content": "Studies on the mode of proliferation of rat liver cells in chronic thioacetamide intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361792"}
{"pmid": "4361793", "title": "Ablation of the primary infero-temporal epileptogenic focus in rhesus monkeys with independent secondary spike discharges.", "content": "Ablation of the primary infero-temporal epileptogenic focus in rhesus monkeys with independent secondary spike discharges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361793"}
{"pmid": "4361795", "title": "Histochemical location of glutamic dehydrogenase and aspartate aminotransferase in chicken cerebellum.", "content": "Histochemical location of glutamic dehydrogenase and aspartate aminotransferase in chicken cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361795"}
{"pmid": "4361794", "title": "Impaired hyperpolarising inhibition during insulin hypoglycaemia and fluoroacetate poisoning.", "content": "Impaired hyperpolarising inhibition during insulin hypoglycaemia and fluoroacetate poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361794"}
{"pmid": "4361802", "title": "Comparative studies on angiotensins. 3. Structure of fowl angiotensin and its identification by DNS-method.", "content": "Comparative studies on angiotensins. 3. Structure of fowl angiotensin and its identification by DNS-method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361802"}
{"pmid": "4361803", "title": "The urinary excretion of 1-methylimidazole-4-acetic acid, a histamine metabolite, by healthy and asthmatic children.", "content": "The urinary excretion of 1-methylimidazole-4-acetic acid, a histamine metabolite, by healthy and asthmatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361803"}
{"pmid": "4361804", "title": "Altered bile acid metabolism during treatment with phenobarbitone.", "content": "Altered bile acid metabolism during treatment with phenobarbitone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361804"}
{"pmid": "4361805", "title": "Triglyceride storage disease: a group of inborn errors of triglyceride metabolism.", "content": "Triglyceride storage disease: a group of inborn errors of triglyceride metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361805"}
{"pmid": "4361806", "title": "Measurable effect (5.0--0.005 pg-ml) of ACTH acting on sections of adrenal cortex.", "content": "Measurable effect (5.0--0.005 pg-ml) of ACTH acting on sections of adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361806"}
{"pmid": "4361807", "title": "Left ventricular function in chronic obstructive pulmonary disease with and without cardiac failure.", "content": "Left ventricular function in chronic obstructive pulmonary disease with and without cardiac failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361807"}
{"pmid": "4361808", "title": "Carbohydrate metabolism in patients with primary hepatocellular carcinoma.", "content": "Carbohydrate metabolism in patients with primary hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361808"}
{"pmid": "4361809", "title": "The relationship of steroid excretions to signs of sexual maturation phenomena in normal male adolescents.", "content": "The relationship of steroid excretions to signs of sexual maturation phenomena in normal male adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361809"}
{"pmid": "4361810", "title": "I-cell disease (mucolipidosis type II). Serum hydrolases in obligate heterozygotes.", "content": "I-cell disease (mucolipidosis type II). Serum hydrolases in obligate heterozygotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361810"}
{"pmid": "4361813", "title": "Non-cytopathic, non-productive infection by herpes simplex viruses types 1 and 2.", "content": "Non-cytopathic, non-productive infection by herpes simplex viruses types 1 and 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361813"}
{"pmid": "4361814", "title": "Transformation of baboon cells with feline sarcoma virus.", "content": "Transformation of baboon cells with feline sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361814"}
{"pmid": "4361812", "title": "Effect of nonspecific factors on focus formation by Rous sarcoma virus. II. Polyanions, divalent cations, temperature, and tryptose phosphate broth.", "content": "Effect of nonspecific factors on focus formation by Rous sarcoma virus. II. Polyanions, divalent cations, temperature, and tryptose phosphate broth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361812"}
{"pmid": "4361815", "title": "Silica urolithiasis in laboratory dogs fed semisynthetic diets.", "content": "Silica urolithiasis in laboratory dogs fed semisynthetic diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361815"}
{"pmid": "4361816", "title": "Effect of sequential inoculations of Sendai virus and Pasteurella pneumotropica in mice.", "content": "Effect of sequential inoculations of Sendai virus and Pasteurella pneumotropica in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361816"}
{"pmid": "4361817", "title": "Binding of 125I-human growth hormone to specific receptors in human cultured lymphocytes. Characterization of the interaction and a sensitive radioreceptor assay.", "content": "Binding of 125I-human growth hormone to specific receptors in human cultured lymphocytes. Characterization of the interaction and a sensitive radioreceptor assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361817"}
{"pmid": "4361818", "title": "Spin-labeled sulfonyl fluorides as active site probes of protease structure. I. Comparison of the active site environments in alpha-chymotrypsin and trypsin.", "content": "Spin-labeled sulfonyl fluorides as active site probes of protease structure. I. Comparison of the active site environments in alpha-chymotrypsin and trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361818"}
{"pmid": "4361820", "title": "Enzymatic synthesis of phosphoribosylamine in human cells.", "content": "Enzymatic synthesis of phosphoribosylamine in human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361820"}
{"pmid": "4361819", "title": "Spin-labeled sulfonyl fluorides as active site probes of protease structure. II. Spin label syntheses and enzyme inhibition.", "content": "Spin-labeled sulfonyl fluorides as active site probes of protease structure. II. Spin label syntheses and enzyme inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361819"}
{"pmid": "4361821", "title": "Kinetic properties of allosteric adenosine monophosphate nucleosidase from Azotobacter vinelandii.", "content": "Kinetic properties of allosteric adenosine monophosphate nucleosidase from Azotobacter vinelandii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361821"}
{"pmid": "4361811", "title": "Propagation in vitro of functional rat adrenal cortical cells: modifications of the differentiated state by culture conditions.", "content": "Propagation in vitro of functional rat adrenal cortical cells: modifications of the differentiated state by culture conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361811"}
{"pmid": "4361822", "title": "On the question of the existence of a guanosine triphosphate-specific protein kinase activated by adenosine 3':5'-monophosphate-dependent protein kinase.", "content": "On the question of the existence of a guanosine triphosphate-specific protein kinase activated by adenosine 3':5'-monophosphate-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361822"}
{"pmid": "4361824", "title": "The effect of isoproterenol upon the activity and intracellular distribution of pyrimidine nucleoside kinases in the mouse parotid gland.", "content": "The effect of isoproterenol upon the activity and intracellular distribution of pyrimidine nucleoside kinases in the mouse parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361824"}
{"pmid": "4361825", "title": "Binding of bacitracin to cells and protoplasts of Micrococcus lysodeikticus.", "content": "Binding of bacitracin to cells and protoplasts of Micrococcus lysodeikticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361825"}
{"pmid": "4361823", "title": "Kinetic studies on the reaction between apocytochrome c peroxidase and protoporphyrin IX.", "content": "Kinetic studies on the reaction between apocytochrome c peroxidase and protoporphyrin IX.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361823"}
{"pmid": "4361826", "title": "The structures of oligosaccharides accumulating in the liver of G-M1-gangliosidosis, type I.", "content": "The structures of oligosaccharides accumulating in the liver of G-M1-gangliosidosis, type I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361826"}
{"pmid": "4361827", "title": "Action of magnesium ion on diphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart. Characterization of the forms of the substrate and the modifier of the reaction.", "content": "Action of magnesium ion on diphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart. Characterization of the forms of the substrate and the modifier of the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361827"}
{"pmid": "4361828", "title": "The molecular mechanism of the in vitro 4 S to 5 S transformation of the uterine estrogen receptor.", "content": "The molecular mechanism of the in vitro 4 S to 5 S transformation of the uterine estrogen receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361828"}
{"pmid": "4361829", "title": "Adenylate kinase in human tissue. I. Organ specificity of adenylate kinase isoenzymes.", "content": "Adenylate kinase in human tissue. I. Organ specificity of adenylate kinase isoenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361829"}
{"pmid": "4361830", "title": "Structure of the carbohydrate units of IgE immunoglobulin. I. Over-all composition, glycopeptide isolation, and structure of the high mannose oligosaccharide unit.", "content": "Structure of the carbohydrate units of IgE immunoglobulin. I. Over-all composition, glycopeptide isolation, and structure of the high mannose oligosaccharide unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361830"}
{"pmid": "4361831", "title": "Structure of the carbohydrate units of IgE immunoglobulin. II. Sequence of the sialic acid-containing glycopeptides.", "content": "Structure of the carbohydrate units of IgE immunoglobulin. II. Sequence of the sialic acid-containing glycopeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361831"}
{"pmid": "4361832", "title": "Inhibition by dithiothreitol of the utilization of glutamine by carbamyl phosphate synthetase. Evidence for formation of hydrogen peroxide.", "content": "Inhibition by dithiothreitol of the utilization of glutamine by carbamyl phosphate synthetase. Evidence for formation of hydrogen peroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361832"}
{"pmid": "4361834", "title": "The Trp-59 fluorescence of ferricytochrome c as a sensitive measure of the over-all protein conformation.", "content": "The Trp-59 fluorescence of ferricytochrome c as a sensitive measure of the over-all protein conformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361834"}
{"pmid": "4361833", "title": "Electron paramagnetic resonance-detectable electron acceptors in beef heart mitochondria. Ubihydroquinone-cytochrome c reductase segment of the electron transfer system and complex mitochondrial fragments.", "content": "Electron paramagnetic resonance-detectable electron acceptors in beef heart mitochondria. Ubihydroquinone-cytochrome c reductase segment of the electron transfer system and complex mitochondrial fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361833"}
{"pmid": "4361836", "title": "Phosphatase activity of some Mycoplasma species.", "content": "Phosphatase activity of some Mycoplasma species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361836"}
{"pmid": "4361835", "title": "Bactericidal effect of antibiotics on Haemophilus influenzae.", "content": "Bactericidal effect of antibiotics on Haemophilus influenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361835"}
{"pmid": "4361839", "title": "Hospital treatment of alcoholism. A new therapeutic concept.", "content": "Hospital treatment of alcoholism. A new therapeutic concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361839"}
{"pmid": "4361840", "title": "The biochemistry of alcohol.", "content": "The biochemistry of alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361840"}
{"pmid": "4361841", "title": "Application of antimony trichloride reagent in biochemical and chemotaxonomic studies relating to diosgenin and yamogenin in plants.", "content": "Application of antimony trichloride reagent in biochemical and chemotaxonomic studies relating to diosgenin and yamogenin in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361841"}
{"pmid": "4361842", "title": "Alteration of ethanol-induced CNS depression: ineffectiveness of drugs that modify cholinergic transmission.", "content": "Alteration of ethanol-induced CNS depression: ineffectiveness of drugs that modify cholinergic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361842"}
{"pmid": "4361844", "title": "Coordinating mental health systems: a national and international perspective.", "content": "Coordinating mental health systems: a national and international perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361844"}
{"pmid": "4361845", "title": "Kinetics and the free-radical mechanisms of tumor growth.", "content": "Kinetics and the free-radical mechanisms of tumor growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361845"}
{"pmid": "4361838", "title": "Herpes simplex infection of HEp-2 and L-929 cells. 2. The kinetics of virus multiplication and cell lysis, and the measurement of interferon production.", "content": "Herpes simplex infection of HEp-2 and L-929 cells. 2. The kinetics of virus multiplication and cell lysis, and the measurement of interferon production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361838"}
{"pmid": "4361846", "title": "Free radical induced in rat liver by a chemical carcinogen, N-methyl-N'-nitro-N-nitrosoguanidine.", "content": "Free radical induced in rat liver by a chemical carcinogen, N-methyl-N'-nitro-N-nitrosoguanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361846"}
{"pmid": "4361837", "title": "The effect of chloroform, phenols, alcohols and cyanogen iodide on the swelling of Pseudomonas aeruginosa in various salts.", "content": "The effect of chloroform, phenols, alcohols and cyanogen iodide on the swelling of Pseudomonas aeruginosa in various salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361837"}
{"pmid": "4361848", "title": "ESR signals during x-irradiation of tissue: their characteristics and relationship to the cancerous state.", "content": "ESR signals during x-irradiation of tissue: their characteristics and relationship to the cancerous state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361848"}
{"pmid": "4361847", "title": "Nuclear magnetic resonance as a new tool in cancer research: human tumors by NMR.", "content": "Nuclear magnetic resonance as a new tool in cancer research: human tumors by NMR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361847"}
{"pmid": "4361849", "title": "Experiences with ESR as a tool for surveying narcotic addiction.", "content": "Experiences with ESR as a tool for surveying narcotic addiction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361849"}
{"pmid": "4361851", "title": "Paramagnetic species and radical products in cat spinal cord.", "content": "Paramagnetic species and radical products in cat spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361851"}
{"pmid": "4361850", "title": "The effect of ambient temperature on spin-label immunoassay for morphine.", "content": "The effect of ambient temperature on spin-label immunoassay for morphine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361850"}
{"pmid": "4361852", "title": "Structural studies of transition state analog complexes of creatine kinase.", "content": "Structural studies of transition state analog complexes of creatine kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361852"}
{"pmid": "4361853", "title": "The use of spin labels for measuring distances in biological systems.", "content": "The use of spin labels for measuring distances in biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361853"}
{"pmid": "4361855", "title": "Magnetic resonance studies of human hemoglobins and their implications to the structure-function relationships in human normal and abnormal hemoglobins.", "content": "Magnetic resonance studies of human hemoglobins and their implications to the structure-function relationships in human normal and abnormal hemoglobins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361855"}
{"pmid": "4361854", "title": "Ligand-enzyme interactions and enzyme regulation.", "content": "Ligand-enzyme interactions and enzyme regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361854"}
{"pmid": "4361856", "title": "NMR relaxation studies of the unfolding and refolding of staphylococcal nuclease at low pH.", "content": "NMR relaxation studies of the unfolding and refolding of staphylococcal nuclease at low pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361856"}
{"pmid": "4361857", "title": "Cytochrome c-nucleotide complexes and the role of unpaired electrons in coupling processes.", "content": "Cytochrome c-nucleotide complexes and the role of unpaired electrons in coupling processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361857"}
{"pmid": "4361858", "title": "EPR and other studies of the anion-binding sites of transferrin.", "content": "EPR and other studies of the anion-binding sites of transferrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361858"}
{"pmid": "4361859", "title": "Ionic free radicals induced by ionizing radiation in oriented DNA.", "content": "Ionic free radicals induced by ionizing radiation in oriented DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361859"}
{"pmid": "4361860", "title": "Effects of metal ions on radical formation in gamma-irradiated DNA in the solid state.", "content": "Effects of metal ions on radical formation in gamma-irradiated DNA in the solid state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361860"}
{"pmid": "4361863", "title": "ESR and ENDOR studies of irradiated nucleic acid constituents.", "content": "ESR and ENDOR studies of irradiated nucleic acid constituents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361863"}
{"pmid": "4361861", "title": "Structure and formation of free radicals in irradiated single crystals of nucleic acid constituents.", "content": "Structure and formation of free radicals in irradiated single crystals of nucleic acid constituents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361861"}
{"pmid": "4361862", "title": "Radiation-induced radicals in thymine and its derivatives in low temperature glasses.", "content": "Radiation-induced radicals in thymine and its derivatives in low temperature glasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361862"}
{"pmid": "4361864", "title": "Long-lived radiation-induced free radicals in anoxic wet DNA as studied by electron spin resonance spectroscopy.", "content": "Long-lived radiation-induced free radicals in anoxic wet DNA as studied by electron spin resonance spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361864"}
{"pmid": "4361865", "title": "Equality of the rates of lateral diffusion of phosphatidylethanolamine and phosphatidylcholine spin labels in rabbit sarcoplasmic reticulum.", "content": "Equality of the rates of lateral diffusion of phosphatidylethanolamine and phosphatidylcholine spin labels in rabbit sarcoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361865"}
{"pmid": "4361866", "title": "The noncovalent coupling of rhodopsin and phosphatidylcholines.", "content": "The noncovalent coupling of rhodopsin and phosphatidylcholines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361866"}
{"pmid": "4361867", "title": "Electron spin resonance studies with the volatile anesthetics on phospholipid model membranes.", "content": "Electron spin resonance studies with the volatile anesthetics on phospholipid model membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361867"}
{"pmid": "4361869", "title": "Boundary lipid and fluid bilayer regions in cytochrome oxidase model membranes.", "content": "Boundary lipid and fluid bilayer regions in cytochrome oxidase model membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361869"}
{"pmid": "4361868", "title": "The measurement of zero field splitting and the determination of ligand composition in mononuclear nonheme iron proteins.", "content": "The measurement of zero field splitting and the determination of ligand composition in mononuclear nonheme iron proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361868"}
{"pmid": "4361870", "title": "Triphosphate spin-label studies of allosteric interactions in hemoglobin.", "content": "Triphosphate spin-label studies of allosteric interactions in hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361870"}
{"pmid": "4361871", "title": "The use of spin labels in the study of muscle proteins.", "content": "The use of spin labels in the study of muscle proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361871"}
{"pmid": "4361872", "title": "Molecular architecture of bilayer membranes.", "content": "Molecular architecture of bilayer membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361872"}
{"pmid": "4361873", "title": "Carbon-13 NMR studies of peptide hormones and their components.", "content": "Carbon-13 NMR studies of peptide hormones and their components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361873"}
{"pmid": "4361875", "title": "Spin-probe analysis of membrane perturbations produced by chemical and physical agents.", "content": "Spin-probe analysis of membrane perturbations produced by chemical and physical agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361875"}
{"pmid": "4361876", "title": "Electron spin resonance in silkworm eggs.", "content": "Electron spin resonance in silkworm eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361876"}
{"pmid": "4361874", "title": "ESR studies of radiation damage in nucleic acids, bases, nucleosides and nucleotides.", "content": "ESR studies of radiation damage in nucleic acids, bases, nucleosides and nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361874"}
{"pmid": "4361878", "title": "Heme-spin-label studies on human hemoglobin.", "content": "Heme-spin-label studies on human hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361878"}
{"pmid": "4361877", "title": "New EPR methods for the study of very slow motion: application to spin-labeled hemoglobin.", "content": "New EPR methods for the study of very slow motion: application to spin-labeled hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361877"}
{"pmid": "4361879", "title": "Anomalous relaxation of water protons in solutions of copper-containing proteins.", "content": "Anomalous relaxation of water protons in solutions of copper-containing proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361879"}
{"pmid": "4361880", "title": "Carbon-13 Fourier transform NMR studies in 20 mm sample tubes: observation of individual carbon sites in proteins.", "content": "Carbon-13 Fourier transform NMR studies in 20 mm sample tubes: observation of individual carbon sites in proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361880"}
{"pmid": "4361881", "title": "ESR and NMR studies with deuterated flavodoxin.", "content": "ESR and NMR studies with deuterated flavodoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361881"}
{"pmid": "4361882", "title": "EPR studies of iron-sulphur proteins of plant mitochondria.", "content": "EPR studies of iron-sulphur proteins of plant mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361882"}
{"pmid": "4361883", "title": "Identification of primary photosynthetic processes.", "content": "Identification of primary photosynthetic processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361883"}
{"pmid": "4361885", "title": "Primary processes in chloroplast photosynthesis: EPR studies of bound ferredoxin and P700.", "content": "Primary processes in chloroplast photosynthesis: EPR studies of bound ferredoxin and P700.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361885"}
{"pmid": "4361884", "title": "The role of plastocyanin in the photosynthetic electron transport chain as studied by EPR spectroscopy.", "content": "The role of plastocyanin in the photosynthetic electron transport chain as studied by EPR spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361884"}
{"pmid": "4361886", "title": "Electron nuclear double resonance (ENDOR) investigation on myoglobin and hemoglobin.", "content": "Electron nuclear double resonance (ENDOR) investigation on myoglobin and hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361886"}
{"pmid": "4361887", "title": "A fast kinetic component of ESR signal II in photosynthesis.", "content": "A fast kinetic component of ESR signal II in photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361887"}
{"pmid": "4361890", "title": "Isolated growth hormone deficiency. Two families with autosomal dominant inheritance.", "content": "Isolated growth hormone deficiency. Two families with autosomal dominant inheritance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361890"}
{"pmid": "4361888", "title": "Congenital adrenal hyperplasia.", "content": "Congenital adrenal hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361888"}
{"pmid": "4361891", "title": "Proceedings: Uses of a routine postmortem radiography.", "content": "Proceedings: Uses of a routine postmortem radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361891"}
{"pmid": "4361889", "title": "Growth and skeletal maturation in congenital adrenal hyperplasia. Review of 20 cases.", "content": "Growth and skeletal maturation in congenital adrenal hyperplasia. Review of 20 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361889"}
{"pmid": "4361892", "title": "Diagnosis and clinical significance of parainfluenza virus infections in children.", "content": "Diagnosis and clinical significance of parainfluenza virus infections in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361892"}
{"pmid": "4361894", "title": "Conformational analysis of a cyclic nucleotide: 3'-5'-adenosine monophosphate. A study based on the extended Hückel theory.", "content": "Conformational analysis of a cyclic nucleotide: 3'-5'-adenosine monophosphate. A study based on the extended Hückel theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361894"}
{"pmid": "4361893", "title": "Multiple forms of protein kinase in liver cell. I. Cytosol.", "content": "Multiple forms of protein kinase in liver cell. I. Cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361893"}
{"pmid": "4361895", "title": "Molecular mobility of polypeptides containing proline as determined by 13C magnetic resonance.", "content": "Molecular mobility of polypeptides containing proline as determined by 13C magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361895"}
{"pmid": "4361898", "title": "Leiomyoma. An unusual tumour of the orbit.", "content": "Leiomyoma. An unusual tumour of the orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361898"}
{"pmid": "4361899", "title": "Diseases of the skin. Treatment of scalp disorders.", "content": "Diseases of the skin. Treatment of scalp disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361899"}
{"pmid": "4361901", "title": "Protein-binding assay for plasma testosterone, after purification by column partition chromatography.", "content": "Protein-binding assay for plasma testosterone, after purification by column partition chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361901"}
{"pmid": "4361900", "title": "Diseases of the skin. Present and future trends in approaches to skin disease.", "content": "Diseases of the skin. Present and future trends in approaches to skin disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361900"}
{"pmid": "4361902", "title": "Advantages and disadvantages of nephelometric measurement of serum lipids.", "content": "Advantages and disadvantages of nephelometric measurement of serum lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361902"}
{"pmid": "4361903", "title": "Directional effects of cyclic AMP on platelets.", "content": "Directional effects of cyclic AMP on platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361903"}
{"pmid": "4361905", "title": "The effect of fetal pituitary ACTH and maternal corticosteroid on the development of fetal rat adrenal cortex.", "content": "The effect of fetal pituitary ACTH and maternal corticosteroid on the development of fetal rat adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361905"}
{"pmid": "4361906", "title": "Metabolism of mammalian sympathetic ganglia.", "content": "Metabolism of mammalian sympathetic ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361906"}
{"pmid": "4361907", "title": "Role of cyclic AMP in synaptic transmission in the mammalian peripheral nervous system.", "content": "Role of cyclic AMP in synaptic transmission in the mammalian peripheral nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361907"}
{"pmid": "4361908", "title": "Physiological significance of protein degradation in animal and bacterial cells.", "content": "Physiological significance of protein degradation in animal and bacterial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361908"}
{"pmid": "4361912", "title": "Ribosomal RNA cistron multiplicity and nucleolar organizers in hexaploid wheat.", "content": "Ribosomal RNA cistron multiplicity and nucleolar organizers in hexaploid wheat. The ribosomal DNA (DNA complementary to ribosomal RNA) content of twelve different wheat genotypes has been studied. Some of these genotypes are aneuploids with deletions or additions of chromosomes bearing nucleolar organisers. The rDNA contents of these genotypes provide several examples of a clear departure from a correlation between the number of rRNA cistrons and the number of nucleolar organisers. Thus the number of rRNA cistrons per nucleolar organiser is not constant in wheat. Wheat DNA was found to have a mean buoyant density of approximately 1.702 g/cc for all genotypes studied and rRNA hybridized selectively to DNA of buoyant density approximately 1.710 g/cc. The thermal stabilities of all the rRNA/DNA hybrids were essentially identical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361912"}
{"pmid": "4361911", "title": "Nineteen paracentric chromosomal inversions in mice.", "content": "Nineteen paracentric chromosomal inversions in mice. Using mutagens on sperm and spermatids we have produced nineteen chromosomal inversions in mice. The levels of radiation and chemical mutagen we used induced inversions in about one per cent of the animals screened. Nine inversions have been transmitted through successive generations, and the particular frequency of first meiotic anaphase bridges manifested by each inversion remained constant. The cytological properties of first meiotic anaphases varied considerably among the inversions. Chromosomal locations of five inversions are known. Four of the five are fully viable in homozygous condition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361911"}
{"pmid": "4361913", "title": "Translocations, the predominant cause of total sterility in sons of mice treated with mutagens.", "content": "Translocations, the predominant cause of total sterility in sons of mice treated with mutagens. Histological and cytological analyses of the testes were carried out in 42 sterile sons of males treated in the spermatozoal or spermatid stage with 250 mg/kg ethyl methanesulfonate (EMS) alone or after prefeeding with butylated hydroxytoluene (BHT); or treated with 200 R X-rays. Of the 42 sterile males, 17 had some mature spermatids, nine were blocked at diakinesis, 15 were blocked in pachytene, and one lacked spermatogenic cells altogether, having Sertoli cells only. Mitotic (spermatogonial) metaphases could therefore be analyzed in 41 of the males and meiotic configurations in 26.-(1) None of the males showed abnormalities in chromosome number, such as monosomy, trisomy, or mosaicism for either of these conditions. Certain classes of chromosome abnormalities that have been found associated with male sterility in other investigations, namely trisomies, XXY's, and X-autosome translocations, are not expected from treatment of 19A + Y cells when F(1) males are studied. (2) A very high percentage of the sterile males carried translocations. Direct meiotic evidence for this was found in 22 of the animals. In addition, 11 of the 16 that were blocked (or virtually blocked) in pachytene, and thus could be analyzed in mitosis only, consistently showed one abnormally short chromosome (or, one short plus one long), which presumably had resulted from unequal exchange (or sizable deficiency). Of the meiotically detected translocation males, 1 carried a T(A;Y), 17 had single autosomal translocations, and 4 had multiple autosomal rearrangements involving three, four, four, and six breaks, respectively. In addition, three males showed failure of X-Y pairing. (3) Translocations that cause sterility, rather than partial sterility, in males appear to be those in which at least one of the breaks occurs close to one end of a chromosome. The mitotic and meiotic evidences for this were found to be correlated. (4) It is proposed that many cases of induced F(1) male sterility may be the result of position effects produced when paracentromeric regions are translocated to euchromatic regions of certain other chromosomes. Since many translocations that produce partial sterility in the female cause complete sterility in the male, the male must be assumed to be more susceptible to disturbances of fertility by the postulated mechanism. (5) There is evidence that EMS, especially in the lower dose range, more often breaks chromosomes near one of their ends than does X-irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361913"}
{"pmid": "4361914", "title": "Studies on the mechanisms of invasion in cancer. 3. Purification of a neutral protease of rat ascites hepatoma cell associated with production of chemotactic factor for cancer cells.", "content": "Studies on the mechanisms of invasion in cancer. 3. Purification of a neutral protease of rat ascites hepatoma cell associated with production of chemotactic factor for cancer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361914"}
{"pmid": "4361916", "title": "Potentiation of RSV rescue from RSV-transformed \"poorly\" virogenic cell lines by 5-bromodeoxyuridine treatment before fusion with chick embryo fibroblasts.", "content": "Potentiation of RSV rescue from RSV-transformed \"poorly\" virogenic cell lines by 5-bromodeoxyuridine treatment before fusion with chick embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361916"}
{"pmid": "4361915", "title": "Immunogenicity of embryonic antigens associated with chemically induced rat tumours.", "content": "Immunogenicity of embryonic antigens associated with chemically induced rat tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361915"}
{"pmid": "4361917", "title": "Further studies on the ability of regressor sera to block cell-mediated destruction of Rous sarcomas.", "content": "Further studies on the ability of regressor sera to block cell-mediated destruction of Rous sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361917"}
{"pmid": "4361918", "title": "Antigenic relatedness of simian C-type viruses.", "content": "Antigenic relatedness of simian C-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361918"}
{"pmid": "4361919", "title": "Sensitivity to guinea-pig serum of hamster cells transformed in vitro by two strains of the Rous sarcoma virus.", "content": "Sensitivity to guinea-pig serum of hamster cells transformed in vitro by two strains of the Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361919"}
{"pmid": "4361920", "title": "Non-specific serum inhibitors of activity of haemagglutinins of rabies and vesicular stomatitis viruses.", "content": "Non-specific serum inhibitors of activity of haemagglutinins of rabies and vesicular stomatitis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361920"}
{"pmid": "4361922", "title": "Interfering particles from a culture persistently infected with Parana virus.", "content": "Interfering particles from a culture persistently infected with Parana virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361922"}
{"pmid": "4361921", "title": "The effect of canavanine on herpes simplex virus replication.", "content": "The effect of canavanine on herpes simplex virus replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361921"}
{"pmid": "4361923", "title": "Lipid and protein organization in vesicular stomatitis and Sindbis viruses.", "content": "Lipid and protein organization in vesicular stomatitis and Sindbis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361923"}
{"pmid": "4361925", "title": "Imaging functional nodules of the adrenal glands with 131-I-19-iodocholesterol.", "content": "Imaging functional nodules of the adrenal glands with 131-I-19-iodocholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361925"}
{"pmid": "4361924", "title": "Scintiscanning of pulmonary diseases with 67Ga-citrate.", "content": "Scintiscanning of pulmonary diseases with 67Ga-citrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361924"}
{"pmid": "4361926", "title": "The toxicity of Sn-pyrophosphate: clinical manifestations prior to acute LD50.", "content": "The toxicity of Sn-pyrophosphate: clinical manifestations prior to acute LD50.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361926"}
{"pmid": "4361927", "title": "99mTc-pyrophosphate for bone imaging.", "content": "99mTc-pyrophosphate for bone imaging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361927"}
{"pmid": "4361928", "title": "Sella turcica salivary transplants in hypophysectomized animals.", "content": "Sella turcica salivary transplants in hypophysectomized animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361928"}
{"pmid": "4361929", "title": "Effect of exogenous and endogenous glucocorticosteroids on the in vitro stimulation of lymphocytes from sedated and awake-restrained healthy baboons.", "content": "Effect of exogenous and endogenous glucocorticosteroids on the in vitro stimulation of lymphocytes from sedated and awake-restrained healthy baboons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361929"}
{"pmid": "4361930", "title": "Supercoiled DNA: hydrodynamic model.", "content": "Supercoiled DNA: hydrodynamic model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361930"}
{"pmid": "4361931", "title": "Cholesterol and cell membrane function: a hypothesis concerning etiology of atherosclerosis.", "content": "Cholesterol and cell membrane function: a hypothesis concerning etiology of atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361931"}
{"pmid": "4361932", "title": "Letter: On the inclusion of spontaneous emission in a neuronic equation of state.", "content": "Letter: On the inclusion of spontaneous emission in a neuronic equation of state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361932"}
{"pmid": "4361934", "title": "An administrative record system for ambulatory facilities.", "content": "An administrative record system for ambulatory facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361934"}
{"pmid": "4361933", "title": "Rickets, American style.", "content": "Rickets, American style.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361933"}
{"pmid": "4361936", "title": "Control of cell division by very lysine rich histone (F1) phosphorylation.", "content": "Control of cell division by very lysine rich histone (F1) phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361936"}
{"pmid": "4361937", "title": "Pressor effect of angiotensin II in sodium replete and deplete rats.", "content": "Pressor effect of angiotensin II in sodium replete and deplete rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361937"}
{"pmid": "4361940", "title": "Primary hyperparathyroidism and peptic ulcer disease.", "content": "Primary hyperparathyroidism and peptic ulcer disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361940"}
{"pmid": "4361939", "title": "The presence of radioimmunoassay renin levels in anephric man.", "content": "The presence of radioimmunoassay renin levels in anephric man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361939"}
{"pmid": "4361941", "title": "Control of and by pH.", "content": "Control of and by pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361941"}
{"pmid": "4361935", "title": "Herpes simplex infection of HEp-2 and L-929 cells. 4. The effect of lysosomal inhibitors.", "content": "Herpes simplex infection of HEp-2 and L-929 cells. 4. The effect of lysosomal inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361935"}
{"pmid": "4361943", "title": "The action of heat, chemicals and disinfectants on swine vesicular disease virus.", "content": "The action of heat, chemicals and disinfectants on swine vesicular disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361943"}
{"pmid": "4361947", "title": "Axon retraction following guanethidine treatment. Studies of sympathetic neurons in vivo.", "content": "Axon retraction following guanethidine treatment. Studies of sympathetic neurons in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361947"}
{"pmid": "4361951", "title": "Further observations on a cytoplasmic structure in the hamster oocyte.", "content": "Further observations on a cytoplasmic structure in the hamster oocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361951"}
{"pmid": "4361948", "title": "Electron microscopic study of rat pituitary primordium in organ culture.", "content": "Electron microscopic study of rat pituitary primordium in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361948"}
{"pmid": "4361949", "title": "Fine structural observations of the pecten oculi capillaries of the chicken. Freeze-etching, scanning and transmission electron microscopic investigations.", "content": "Fine structural observations of the pecten oculi capillaries of the chicken. Freeze-etching, scanning and transmission electron microscopic investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361949"}
{"pmid": "4361950", "title": "Sizes of granular vesicles in the rat median eminence, with special reference to the zona granulosa.", "content": "Sizes of granular vesicles in the rat median eminence, with special reference to the zona granulosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361950"}
{"pmid": "4361952", "title": "Absorption of protein macromolecules by the enterocytes of the carp (Cyprinus carpio L.). Ultrastructural and cytochemical study.", "content": "Absorption of protein macromolecules by the enterocytes of the carp (Cyprinus carpio L.). Ultrastructural and cytochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361952"}
{"pmid": "4361953", "title": "The structure of the salivary gland of the moth (Manduca sexta).", "content": "The structure of the salivary gland of the moth (Manduca sexta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361953"}
{"pmid": "4361956", "title": "The proteins of plasma lipoproteins: properties and significance.", "content": "The proteins of plasma lipoproteins: properties and significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361956"}
{"pmid": "4361957", "title": "Peripheral neuropathy presenting with respiratory insufficiency as the primary complaint. Problem of recognizing alveolar hypoventilation due to neuromuscular disorders.", "content": "Peripheral neuropathy presenting with respiratory insufficiency as the primary complaint. Problem of recognizing alveolar hypoventilation due to neuromuscular disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361957"}
{"pmid": "4361959", "title": "Fatal disseminated herpesvirus hominis type 2 infection in an adult with associated thymic dysplasia.", "content": "Fatal disseminated herpesvirus hominis type 2 infection in an adult with associated thymic dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361959"}
{"pmid": "4361958", "title": "Adult meningoencephalitis caused by herpesvirus hominis type 2.", "content": "Adult meningoencephalitis caused by herpesvirus hominis type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361958"}
{"pmid": "4361960", "title": "Chromosomal analysis in malignant ovarian tumors.", "content": "Chromosomal analysis in malignant ovarian tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361960"}
{"pmid": "4361962", "title": "Lipoprotein deficiency disorders.", "content": "Lipoprotein deficiency disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361962"}
{"pmid": "4361961", "title": "The synthesis of matrix components by chondrocytes in vitro in the presence of 5-bromodeoxyuridine.", "content": "The synthesis of matrix components by chondrocytes in vitro in the presence of 5-bromodeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361961"}
{"pmid": "4361963", "title": "Type II hyperlipoproteinaemia.", "content": "Type II hyperlipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361963"}
{"pmid": "4361964", "title": "Tentative method of analysis for cadmium content of atmospheric particulate matter by atomic absorption spectroscopy.", "content": "Tentative method of analysis for cadmium content of atmospheric particulate matter by atomic absorption spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361964"}
{"pmid": "4361966", "title": "Tentative method of analysis for lead content of atmospheric particulate matter by atomic absorption spectroscopy.", "content": "Tentative method of analysis for lead content of atmospheric particulate matter by atomic absorption spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361966"}
{"pmid": "4361965", "title": "Tentative method of analysis for iron content of atmospheric particulate matter by atomic absorption spectroscopy.", "content": "Tentative method of analysis for iron content of atmospheric particulate matter by atomic absorption spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361965"}
{"pmid": "4361967", "title": "Tentative method of analysis for manganese content of atmospheric particulate matter by atomic absorption spectroscopy.", "content": "Tentative method of analysis for manganese content of atmospheric particulate matter by atomic absorption spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361967"}
{"pmid": "4361969", "title": "Fixation of manganese on quartz, limestone, dolomite and marine sediment samples.", "content": "Fixation of manganese on quartz, limestone, dolomite and marine sediment samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361969"}
{"pmid": "4361968", "title": "Tentative method of analysis for zinc content of atmospheric particulate matter by atomic absorption spectroscopy.", "content": "Tentative method of analysis for zinc content of atmospheric particulate matter by atomic absorption spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361968"}
{"pmid": "4361970", "title": "Lung cancer among uranium miners in the United States.", "content": "Lung cancer among uranium miners in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361970"}
{"pmid": "4361971", "title": "An evaluation of the 20 minute perchlorate discharge test.", "content": "An evaluation of the 20 minute perchlorate discharge test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361971"}
{"pmid": "4361972", "title": "A simplified radioimmunoassay of plasma aldosterone.", "content": "A simplified radioimmunoassay of plasma aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361972"}
{"pmid": "4361973", "title": "Effect of various ACTH preparations and of metyrapone on the secretion of growth hormone in normal subjects and in hypopituitary patients.", "content": "Effect of various ACTH preparations and of metyrapone on the secretion of growth hormone in normal subjects and in hypopituitary patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361973"}
{"pmid": "4361974", "title": "The nocturnal rise of human prolactin is dependent on sleep.", "content": "The nocturnal rise of human prolactin is dependent on sleep. Further evidence that there is a relationship between prolactin rise and sleep is offered by this study that delayed sleep onset and inverted the normal sleep-waking cycle in 4 normal patients (3 women and 1 man).  The inversion schedule lasted 3 weeks, and at its conclusion a final 12-hour laboratory study was carried out measuring the plasma levels of human prolactin and growth hormone by radioimmunoassay.  In the first female subject, mean prolactin levels (ng/ml) were, for baseline and after shift, 7 and 8.3; for case 2 (female) the values were 7.3 and 5.9; for case 3 (male) the levels were 6.1 and 6.1; and for the last case, the levels were 4.7 and 4.3, respectively.  Values for growth hormone were (ng/ml) 1.5 and 1.5 for Case 1 for baseline and after shift, respectively; 1.1 and 2.5 for Case 2, respectively; 1.8 and 1.1 for Case 3, respectively; and 7.3 and 5.2 for Case 4, respectively.  Prolactin release shifted immediately and completely with shifts of sleep onset of 3, 6, and 12 hours.  Thus, it is concluded that the nocturnal rise is dependent on the occurrence of sleep, not on the inherent rhythm related to time of day.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361974"}
{"pmid": "4361975", "title": "The urinary excretion of adenosine 3',5'-monophosphate in children and adolescents.", "content": "The urinary excretion of adenosine 3',5'-monophosphate in children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361975"}
{"pmid": "4361976", "title": "Detection of specific surface antigens on cells transformed by cytomegalovirus with the techniques of mixed hemagglutination and 125I-labeled antiglobulin.", "content": "Detection of specific surface antigens on cells transformed by cytomegalovirus with the techniques of mixed hemagglutination and 125I-labeled antiglobulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361976"}
{"pmid": "4361977", "title": "Immunity to murine sarcoma virus-inducted tumors. I. Specific T lymphocytes active in macrophage migration inhibition and lymphocyte transformation.", "content": "Immunity to murine sarcoma virus-inducted tumors. I. Specific T lymphocytes active in macrophage migration inhibition and lymphocyte transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361977"}
{"pmid": "4361978", "title": "Immunity to murine sarcoma virus-inducted tumors. II. Suppression of T cell-mediated immunity by cells from progressor animals.", "content": "Immunity to murine sarcoma virus-inducted tumors. II. Suppression of T cell-mediated immunity by cells from progressor animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361978"}
{"pmid": "4361979", "title": "Phagocytosis: a defense mechanism against infection with Trypanosoma cruzi.", "content": "Phagocytosis: a defense mechanism against infection with Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361979"}
{"pmid": "4361980", "title": "Periodate-induced lymphocyte transformation. IV. Mitogenic effect of NaIO4 treated lymphocytes upon autologous lymphocytes.", "content": "Periodate-induced lymphocyte transformation. IV. Mitogenic effect of NaIO4 treated lymphocytes upon autologous lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361980"}
{"pmid": "4361981", "title": "Reversal of tumor-mediated suppression of immune reactivity by in vitro incubation of spleen cells.", "content": "Reversal of tumor-mediated suppression of immune reactivity by in vitro incubation of spleen cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361981"}
{"pmid": "4361982", "title": "A comparative study of the ultrastructure of the sebaceous glands of man and other primates.", "content": "A comparative study of the ultrastructure of the sebaceous glands of man and other primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361982"}
{"pmid": "4361983", "title": "Hormonal control and methods of measuring sebaceous gland activity.", "content": "Hormonal control and methods of measuring sebaceous gland activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361983"}
{"pmid": "4361984", "title": "The control and measurement of sebum secretion.", "content": "The control and measurement of sebum secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361984"}
{"pmid": "4361985", "title": "Endocrinologic control of the development and activity of the human sebaceous gland.", "content": "Endocrinologic control of the development and activity of the human sebaceous gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361985"}
{"pmid": "4361986", "title": "Receptor proteins for androgen in hamster sebaceous glands.", "content": "Receptor proteins for androgen in hamster sebaceous glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361986"}
{"pmid": "4361987", "title": "Inhibition of dihydrotestosterone formation: an effective means of blocking androgen action in hamster sebaceous gland.", "content": "Inhibition of dihydrotestosterone formation: an effective means of blocking androgen action in hamster sebaceous gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361987"}
{"pmid": "4361988", "title": "Ultrastructural observations in acne vulgaris: the normal sebaceous follicle and acne lesions.", "content": "Ultrastructural observations in acne vulgaris: the normal sebaceous follicle and acne lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361988"}
{"pmid": "4361989", "title": "Proceedings: Reinnervation of skeletal muscle in the mouse.", "content": "Proceedings: Reinnervation of skeletal muscle in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361989"}
{"pmid": "4361990", "title": "Cancer of the lung in young men.", "content": "Cancer of the lung in young men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361990"}
{"pmid": "4361993", "title": "Dual action of praseodymium (Pr3+) on transmitter release at the frog neuromuscular synapse.", "content": "Dual action of praseodymium (Pr3+) on transmitter release at the frog neuromuscular synapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361993"}
{"pmid": "4361992", "title": "Sensitivity to amphotericin B of in vitro established cell lines.", "content": "Sensitivity to amphotericin B of in vitro established cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361992"}
{"pmid": "4361995", "title": "Morphine-like drugs inhibit the stimulation of E prostaglandins of cyclic AMP formation by rat brain homogenate.", "content": "Morphine-like drugs inhibit the stimulation of E prostaglandins of cyclic AMP formation by rat brain homogenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361995"}
{"pmid": "4361994", "title": "Interaction of mercurials with salmon serum lipoproteins.", "content": "Interaction of mercurials with salmon serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361994"}
{"pmid": "4361996", "title": "Inhibitor of vesicular stomatitis virus transcriptase in purified virions.", "content": "Inhibitor of vesicular stomatitis virus transcriptase in purified virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361996"}
{"pmid": "4361991", "title": "Methionine transfer RNAs associated with avian oncornavirus 70S RNA.", "content": "Methionine transfer RNAs associated with avian oncornavirus 70S RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361991"}
{"pmid": "4361999", "title": "Growth hormone releasing factor of microbial origin.", "content": "Growth hormone releasing factor of microbial origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361999"}
{"pmid": "4361997", "title": "Light-regulated guanosine 3',5'-monophosphate phosphodiesterase of bovine retina.", "content": "Light-regulated guanosine 3',5'-monophosphate phosphodiesterase of bovine retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361997"}
{"pmid": "4361998", "title": "Similarity in the sequence of Escherichia coli dihydrofolate reductase with other pyridine nucleotide-requiring enzymes.", "content": "Similarity in the sequence of Escherichia coli dihydrofolate reductase with other pyridine nucleotide-requiring enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4361998"}
{"pmid": "4362000", "title": "Augmentation of cytotoxic drug action by antibodies directed at cell surface.", "content": "Augmentation of cytotoxic drug action by antibodies directed at cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362000"}
{"pmid": "4362002", "title": "Quantitative aspects of interferon-induced plaque reduction: effects of cell age and dose of challenge virus.", "content": "Quantitative aspects of interferon-induced plaque reduction: effects of cell age and dose of challenge virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362002"}
{"pmid": "4362001", "title": "Studies on the anterior pituitary hormones of the kangaroo.", "content": "Studies on the anterior pituitary hormones of the kangaroo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362001"}
{"pmid": "4362003", "title": "Antibodies to viruses of human origin in monkeys from Uganda.", "content": "Antibodies to viruses of human origin in monkeys from Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362003"}
{"pmid": "4362004", "title": "Oral induction of interferon by a low-molecular-weight compound.", "content": "Oral induction of interferon by a low-molecular-weight compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362004"}
{"pmid": "4362005", "title": "Reciprocal relationship between the in vitro synthesis and secretion of prolactin and growth hormone.", "content": "Reciprocal relationship between the in vitro synthesis and secretion of prolactin and growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362005"}
{"pmid": "4362006", "title": "Studies on the prevalence of endogenous type C virus RD 114 in cats.", "content": "Studies on the prevalence of endogenous type C virus RD 114 in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362006"}
{"pmid": "4362007", "title": "Comparison of the ribonucleotide with the canavanine reductase system.", "content": "Comparison of the ribonucleotide with the canavanine reductase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362007"}
{"pmid": "4362008", "title": "The inhibition of virus adsorption by substances induced by DEAE-dextran and poly I:C.", "content": "The inhibition of virus adsorption by substances induced by DEAE-dextran and poly I:C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362008"}
{"pmid": "4362009", "title": "The response of glucose-6-phosphatase in human and rat fetal liver cultures to dibutyryl cyclic AMP.", "content": "The response of glucose-6-phosphatase in human and rat fetal liver cultures to dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362009"}
{"pmid": "4362011", "title": "Effect of the inhibition of angiotensin I converting enzyme in endotoxin and hemorrhagic shock.", "content": "Effect of the inhibition of angiotensin I converting enzyme in endotoxin and hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362011"}
{"pmid": "4362010", "title": "The conjugation of bilirubin by rat hepatoma cells in tissue culture.", "content": "The conjugation of bilirubin by rat hepatoma cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362010"}
{"pmid": "4362013", "title": "Fanconi's anaemia.", "content": "Fanconi's anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362013"}
{"pmid": "4362012", "title": "Stimulation and suppression of erythropoiesis in the plethoric mouse by cyclic nucleotides.", "content": "Stimulation and suppression of erythropoiesis in the plethoric mouse by cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362012"}
{"pmid": "4362015", "title": "Dietary factors affecting the pathogenicity of Entamoeba histolytica in rats.", "content": "Dietary factors affecting the pathogenicity of Entamoeba histolytica in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362015"}
{"pmid": "4362014", "title": "Glioblastoma multiforme of the spinal cord.", "content": "Glioblastoma multiforme of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362014"}
{"pmid": "4362016", "title": "In vitro activity of metronidazole on Entamoeba histolytica in axenic culture.", "content": "In vitro activity of metronidazole on Entamoeba histolytica in axenic culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362016"}
{"pmid": "4362017", "title": "Proceedings: The interaction between E. histolytica and rabbit kidney cell (RK13) monolayers.", "content": "Proceedings: The interaction between E. histolytica and rabbit kidney cell (RK13) monolayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362017"}
{"pmid": "4362018", "title": "Proceedings: Rhabdo-virus like particles of Entamoeba histolytica.", "content": "Proceedings: Rhabdo-virus like particles of Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362018"}
{"pmid": "4362019", "title": "Study of Naegleria aerobia by electron microscopy.", "content": "Study of Naegleria aerobia by electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362019"}
{"pmid": "4362020", "title": "Properties of the polyoma virus transcription complex obtained from mouse nuclei.", "content": "Properties of the polyoma virus transcription complex obtained from mouse nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362020"}
{"pmid": "4362021", "title": "Recombination between temperature-sensitive mutants of simian virus 40.", "content": "Recombination between temperature-sensitive mutants of simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362021"}
{"pmid": "4362022", "title": "C-type particles produced by a permanent cell line from a leukemic pig. I. Origin and properties of the host cells and some evidence for the occurrence of C-type-like particles.", "content": "C-type particles produced by a permanent cell line from a leukemic pig. I. Origin and properties of the host cells and some evidence for the occurrence of C-type-like particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362022"}
{"pmid": "4362023", "title": "Endonucleolytic DNase in oncorna viruses: role of mycoplasma.", "content": "Endonucleolytic DNase in oncorna viruses: role of mycoplasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362023"}
{"pmid": "4362024", "title": "A comparison of the high molecular weight RNAs of visna virus and Rous sarcoma virus.", "content": "A comparison of the high molecular weight RNAs of visna virus and Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362024"}
{"pmid": "4362025", "title": "Pseudotypes of vesicular stomatitis virus determined by exogenous and endogenous avian RNA tumor viruses.", "content": "Pseudotypes of vesicular stomatitis virus determined by exogenous and endogenous avian RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362025"}
{"pmid": "4362027", "title": "Membrane alterations which accompany MuMTV maturation. I. Studies by freeze-cleave techniques.", "content": "Membrane alterations which accompany MuMTV maturation. I. Studies by freeze-cleave techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362027"}
{"pmid": "4362026", "title": "Stimulation of fetal thymidine kinase in cultured human fibroblasts transformed by SV40 virus.", "content": "Stimulation of fetal thymidine kinase in cultured human fibroblasts transformed by SV40 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362026"}
{"pmid": "4362028", "title": "Enhancing factor for Rous sarcoma virus: in vitro assay and action on both cells and virus.", "content": "Enhancing factor for Rous sarcoma virus: in vitro assay and action on both cells and virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362028"}
{"pmid": "4362029", "title": "Accumulation of closed-circular polyoma DNA molecules containing host DNA during serial passage of the virus.", "content": "Accumulation of closed-circular polyoma DNA molecules containing host DNA during serial passage of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362029"}
{"pmid": "4362031", "title": "Extravesical malakoplakia.", "content": "Extravesical malakoplakia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362031"}
{"pmid": "4362032", "title": "Herpesvirus varicellae isolated from human dorsal root ganglia.", "content": "Herpesvirus varicellae isolated from human dorsal root ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362032"}
{"pmid": "4362033", "title": "Chemotherapy of breast cancer. Investigational treatment.", "content": "Chemotherapy of breast cancer. Investigational treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362033"}
{"pmid": "4362035", "title": "Agents which block the action of the renin-angiotensin system.", "content": "Agents which block the action of the renin-angiotensin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362035"}
{"pmid": "4362036", "title": "Senescence and the renal vasculature in normal man.", "content": "Senescence and the renal vasculature in normal man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362036"}
{"pmid": "4362037", "title": "Inhibition by acetylcholine of adrenergic neurotransmission in vascular smooth muscle.", "content": "Inhibition by acetylcholine of adrenergic neurotransmission in vascular smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362037"}
{"pmid": "4362039", "title": "Effect of synthetic LH-releasing factor (LRF) on LH secretion in monolayer cultures of the anterior pituitary cells of cynomolgus monkeys.", "content": "Effect of synthetic LH-releasing factor (LRF) on LH secretion in monolayer cultures of the anterior pituitary cells of cynomolgus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362039"}
{"pmid": "4362041", "title": "A specific progesterone receptor in the hamster uterus: physiologic properties and regulation during the estrous cycle.", "content": "A specific progesterone receptor in the hamster uterus: physiologic properties and regulation during the estrous cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362041"}
{"pmid": "4362040", "title": "Stimulation of 14C-cyclic AMP accumulation by FSH and LH in testis from mature and immature rats.", "content": "Stimulation of 14C-cyclic AMP accumulation by FSH and LH in testis from mature and immature rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362040"}
{"pmid": "4362042", "title": "Hypophyseal-adrenocortical role in urinary excretion of epinephrine and norepinephrine in hypophysectomized and adrenalectomized rats.", "content": "Hypophyseal-adrenocortical role in urinary excretion of epinephrine and norepinephrine in hypophysectomized and adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362042"}
{"pmid": "4362044", "title": "Action of a nonsteroidal antiandrogen, flutamide, on the receptor binding and nuclear retention of 5 alpha-dihydrotestosterone in rat ventral prostate.", "content": "Action of a nonsteroidal antiandrogen, flutamide, on the receptor binding and nuclear retention of 5 alpha-dihydrotestosterone in rat ventral prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362044"}
{"pmid": "4362043", "title": "Effects of colchicine on the formation of thyroid hormone.", "content": "Effects of colchicine on the formation of thyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362043"}
{"pmid": "4362038", "title": "Evidence for different angiotensin II receptors in rat adrenal glomerulosa and rabbit vascular smooth muscle cells. Studies with competitive antagonists.", "content": "Evidence for different angiotensin II receptors in rat adrenal glomerulosa and rabbit vascular smooth muscle cells. Studies with competitive antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362038"}
{"pmid": "4362045", "title": "Acute hormonal regulation of cyclic AMP content and glycogen phosphorylase activity in fetal liver in organ culture.", "content": "Acute hormonal regulation of cyclic AMP content and glycogen phosphorylase activity in fetal liver in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362045"}
{"pmid": "4362046", "title": "Rat placental delta-5-3 beta-hydroxysteroid dehydrogenase. I. Changes in activity with dilution and gestational age.", "content": "Rat placental delta-5-3 beta-hydroxysteroid dehydrogenase. I. Changes in activity with dilution and gestational age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362046"}
{"pmid": "4362047", "title": "General presence of glucocorticoid receptors in mammalian tissues.", "content": "General presence of glucocorticoid receptors in mammalian tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362047"}
{"pmid": "4362049", "title": "Response of somatosensory cerebral neurons to stimulation of dorsal and dorsolateral spinal funiculi.", "content": "Response of somatosensory cerebral neurons to stimulation of dorsal and dorsolateral spinal funiculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362049"}
{"pmid": "4362048", "title": "Effects of projected cortical epileptiform discharges on unit activity in the cat cuneate nucleus.", "content": "Effects of projected cortical epileptiform discharges on unit activity in the cat cuneate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362048"}
{"pmid": "4362050", "title": "The receptive surface and axonal terminals in severely denervated neurons within the lumbosacral cord of the dog.", "content": "The receptive surface and axonal terminals in severely denervated neurons within the lumbosacral cord of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362050"}
{"pmid": "4362053", "title": "The development of unit activity in the lateral geniculate nucleus of the kitten.", "content": "The development of unit activity in the lateral geniculate nucleus of the kitten.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362053"}
{"pmid": "4362054", "title": "Effects of projected cortical epileptiform discharges on field potentials in the cat cuneate nucleus.", "content": "Effects of projected cortical epileptiform discharges on field potentials in the cat cuneate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362054"}
{"pmid": "4362052", "title": "Ontogenesis of ponto-geniculo-occipital activity in the lateral geniculate nucleus of the kitten.", "content": "Ontogenesis of ponto-geniculo-occipital activity in the lateral geniculate nucleus of the kitten.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362052"}
{"pmid": "4362051", "title": "Electrical and chemosensitive properties of normal and dystrophic chicken muscles.", "content": "Electrical and chemosensitive properties of normal and dystrophic chicken muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362051"}
{"pmid": "4362055", "title": "Adenine arabinoside effect on experimental idoxuridine-resistant herpes simplex infection.", "content": "Adenine arabinoside effect on experimental idoxuridine-resistant herpes simplex infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362055"}
{"pmid": "4362056", "title": "Role of Ca2+ in adrenocorticotropic hormone-stimulated lipolysis in the perfused fat cell system.", "content": "Role of Ca2+ in adrenocorticotropic hormone-stimulated lipolysis in the perfused fat cell system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362056"}
{"pmid": "4362057", "title": "Ascorbate oxidase. Inhibition, activation, and pH effects.", "content": "Ascorbate oxidase. Inhibition, activation, and pH effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362057"}
{"pmid": "4362058", "title": "Activation of succinate dehydrogenase by anions and pH.", "content": "Activation of succinate dehydrogenase by anions and pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362058"}
{"pmid": "4362059", "title": "Lipogenesis in rat hepatocytes.", "content": "Lipogenesis in rat hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362059"}
{"pmid": "4362060", "title": "Studies on human beta-D-N-acetylhexosaminidases. I. Purification and properties.", "content": "Studies on human beta-D-N-acetylhexosaminidases. I. Purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362060"}
{"pmid": "4362061", "title": "Interaction of fragment A from diphtheria toxin with nicotinamide adenine dinucleotide.", "content": "Interaction of fragment A from diphtheria toxin with nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362061"}
{"pmid": "4362062", "title": "Glucocorticoid receptors in mouse mammary tumors. Specific binding of glucocorticoids in the cytoplasm.", "content": "Glucocorticoid receptors in mouse mammary tumors. Specific binding of glucocorticoids in the cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362062"}
{"pmid": "4362063", "title": "Studies on cobalt myoglobins and hemoglobins. 3. Electron paramagnetic resonance studies of reversible oxygenation of cobalt myoglobins and hemoglobins.", "content": "Studies on cobalt myoglobins and hemoglobins. 3. Electron paramagnetic resonance studies of reversible oxygenation of cobalt myoglobins and hemoglobins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362063"}
{"pmid": "4362064", "title": "Univalent reduction of molecular oxygen by spinach chloroplasts on illumination.", "content": "Univalent reduction of molecular oxygen by spinach chloroplasts on illumination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362064"}
{"pmid": "4362065", "title": "Effect of insulin and lipolytic agents on rat adipocyte low Km cyclic adenosine 3':5'-monophosphate phosphodiesterase.", "content": "Effect of insulin and lipolytic agents on rat adipocyte low Km cyclic adenosine 3':5'-monophosphate phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362065"}
{"pmid": "4362066", "title": "Characterization and solubilization of gonadotropin receptor of bovine corpus luteum.", "content": "Characterization and solubilization of gonadotropin receptor of bovine corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362066"}
{"pmid": "4362067", "title": "Purification and characterization of lipoprotein lipase from pig adipose tissue.", "content": "Purification and characterization of lipoprotein lipase from pig adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362067"}
{"pmid": "4362068", "title": "Metalloflavoprotein models. The crystal structure of bis(riboflavin) bis(cupric perchlorate) dodecahydrate.", "content": "Metalloflavoprotein models. The crystal structure of bis(riboflavin) bis(cupric perchlorate) dodecahydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362068"}
{"pmid": "4362069", "title": "Quantitative aspects of the insulin-receptor interaction in liver plasma membranes.", "content": "Quantitative aspects of the insulin-receptor interaction in liver plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362069"}
{"pmid": "4362070", "title": "Biochemical studies on the mode of action of cytochalasin B. Preparation of (3H)cytochalasin B and studies on its binding of cells.", "content": "Biochemical studies on the mode of action of cytochalasin B. Preparation of (3H)cytochalasin B and studies on its binding of cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362070"}
{"pmid": "4362071", "title": "A kinetic study of the complementation of fragments of staphylococcal nuclease.", "content": "A kinetic study of the complementation of fragments of staphylococcal nuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362071"}
{"pmid": "4362072", "title": "Characterization of cardiac muscle collagen. Molecular heterogeneity.", "content": "Characterization of cardiac muscle collagen. Molecular heterogeneity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362072"}
{"pmid": "4362073", "title": "Membrane-bound angiotensin-converting enzyme from rat lung.", "content": "Membrane-bound angiotensin-converting enzyme from rat lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362073"}
{"pmid": "4362074", "title": "Multiple disc gel bands of mitochondrial creatine and adenylate kinases.", "content": "Multiple disc gel bands of mitochondrial creatine and adenylate kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362074"}
{"pmid": "4362075", "title": "Phosphoinositide metabolism in rat superior cervical ganglion, vagus and phrenic nerve: effects of electrical stimulation and various blocking agents.", "content": "Phosphoinositide metabolism in rat superior cervical ganglion, vagus and phrenic nerve: effects of electrical stimulation and various blocking agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362075"}
{"pmid": "4362076", "title": "Synaptosomal plasma membranes: acyl group composition of phosphoglycerides and (Na+ plus K+)-ATPase activity during fatty acid deficiency.", "content": "Synaptosomal plasma membranes: acyl group composition of phosphoglycerides and (Na+ plus K+)-ATPase activity during fatty acid deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362076"}
{"pmid": "4362077", "title": "Effect of behavioural training on brain transfer RNA methylases.", "content": "Effect of behavioural training on brain transfer RNA methylases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362077"}
{"pmid": "4362078", "title": "Effects of levorphanol on phospholipid metabolism in the giant axon of the squid.", "content": "Effects of levorphanol on phospholipid metabolism in the giant axon of the squid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362078"}
{"pmid": "4362081", "title": "Melanoameloblastoma.", "content": "Melanoameloblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362081"}
{"pmid": "4362080", "title": "Cyclic nucleotide phosphodiesterase of the bovine retina: activity, subcellular distribution and kinetic parameters.", "content": "Cyclic nucleotide phosphodiesterase of the bovine retina: activity, subcellular distribution and kinetic parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362080"}
{"pmid": "4362079", "title": "Calcium metabolism in isolated brain cells and subcellular fractions.", "content": "Calcium metabolism in isolated brain cells and subcellular fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362079"}
{"pmid": "4362083", "title": "Editorial: The gene for the poliovirus receptor.", "content": "Editorial: The gene for the poliovirus receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362083"}
{"pmid": "4362084", "title": "Pathogenesis of experimental viral hepatitis (second of two parts).", "content": "Pathogenesis of experimental viral hepatitis (second of two parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362084"}
{"pmid": "4362082", "title": "ACTH and the regulation of adrenocortical secretion.", "content": "ACTH and the regulation of adrenocortical secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362082"}
{"pmid": "4362085", "title": "Possible involvement of cyclic GMP in growth control of cultured mouse cells.", "content": "Possible involvement of cyclic GMP in growth control of cultured mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362085"}
{"pmid": "4362086", "title": "Dramatic early increase in uterine eosinophils after oestrogen administration.", "content": "Dramatic early increase in uterine eosinophils after oestrogen administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362086"}
{"pmid": "4362087", "title": "Thymine-labelled deoxyoligonucleotide involved in DNA chain growth in Bacillus subtilis.", "content": "Thymine-labelled deoxyoligonucleotide involved in DNA chain growth in Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362087"}
{"pmid": "4362088", "title": "Protease inhibitors do not block transformed cells in the G1 phase of the cell cycle.", "content": "Protease inhibitors do not block transformed cells in the G1 phase of the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362088"}
{"pmid": "4362090", "title": "Viroids and viral hepatitis in marmosets.", "content": "Viroids and viral hepatitis in marmosets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362090"}
{"pmid": "4362089", "title": "Detection by DNA polymerase I of breaks produced in rat liver chromatin in vivo by alklating agents.", "content": "Detection by DNA polymerase I of breaks produced in rat liver chromatin in vivo by alklating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362089"}
{"pmid": "4362092", "title": "Community psychiatry at UCLA: a decade of training.", "content": "Community psychiatry at UCLA: a decade of training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362092"}
{"pmid": "4362093", "title": "Effects of cyclopropane on contractility and the cyclic 3',5'-adenosine monophosphate system in the rat aorta.", "content": "Effects of cyclopropane on contractility and the cyclic 3',5'-adenosine monophosphate system in the rat aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362093"}
{"pmid": "4362096", "title": "Oral medicine for the dental practitioner. 2. Infections of the oral mucosa.", "content": "Oral medicine for the dental practitioner. 2. Infections of the oral mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362096"}
{"pmid": "4362097", "title": "The epidermis and cyclic AMP.", "content": "The epidermis and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362097"}
{"pmid": "4362098", "title": "Proceedings: Giant glomangioma.", "content": "Proceedings: Giant glomangioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362098"}
{"pmid": "4362099", "title": "Editorial: Unsuspected cytomegalic mononucleosis.", "content": "Editorial: Unsuspected cytomegalic mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362099"}
{"pmid": "4362100", "title": "Cure of insulin-dependent diabetes mellitus by removal of a glucagonoma.", "content": "Cure of insulin-dependent diabetes mellitus by removal of a glucagonoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362100"}
{"pmid": "4362101", "title": "The effect of pancuronium on reflex regulation of heart rate in man.", "content": "The effect of pancuronium on reflex regulation of heart rate in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362101"}
{"pmid": "4362103", "title": "Lack of thrombohemorrhagic phenomena complicating childhood solid tumors.", "content": "Lack of thrombohemorrhagic phenomena complicating childhood solid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362103"}
{"pmid": "4362104", "title": "Pemphigus vulgaris and internal malignancy.", "content": "Pemphigus vulgaris and internal malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362104"}
{"pmid": "4362102", "title": "Cerebral response to hypocapnia in normal and brain-injured dogs.", "content": "Cerebral response to hypocapnia in normal and brain-injured dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362102"}
{"pmid": "4362105", "title": "Herpes esophagitis complicating Hodgkin's disease.", "content": "Herpes esophagitis complicating Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362105"}
{"pmid": "4362106", "title": "A survival study of intestinal and diffuse types of gastric carcinoma.", "content": "A survival study of intestinal and diffuse types of gastric carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362106"}
{"pmid": "4362107", "title": "The treatment of malignant pleural effusions.", "content": "The treatment of malignant pleural effusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362107"}
{"pmid": "4362108", "title": "Differential diagnosis of breast tumors. The sensitivity graded method ultrasonotomography and clinical evaluation of its diagnostic accuracy.", "content": "Differential diagnosis of breast tumors. The sensitivity graded method ultrasonotomography and clinical evaluation of its diagnostic accuracy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362108"}
{"pmid": "4362094", "title": "Secretory otitis media: protein and enzyme analyses.", "content": "Secretory otitis media: protein and enzyme analyses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362094"}
{"pmid": "4362109", "title": "Serum alpha-fetoprotein in 184 Ugandan patients with hepatocellular carcinoma. Clinical, laboratory, and histopathologic correlations.", "content": "Serum alpha-fetoprotein in 184 Ugandan patients with hepatocellular carcinoma. Clinical, laboratory, and histopathologic correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362109"}
{"pmid": "4362110", "title": "A note on differentiation and divisibility of alveolar epithelial cells.", "content": "A note on differentiation and divisibility of alveolar epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362110"}
{"pmid": "4362111", "title": "Scanning electronmicroscopy of virus-infected respiratory epithelium.", "content": "Scanning electronmicroscopy of virus-infected respiratory epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362111"}
{"pmid": "4362112", "title": "Morphologic and ultrastructural changes in the lungs of animals during acute exposure to ozone.", "content": "Morphologic and ultrastructural changes in the lungs of animals during acute exposure to ozone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362112"}
{"pmid": "4362113", "title": "Fibrous histiocytoma of the lung (sclerosing hemangioma variant?).", "content": "Fibrous histiocytoma of the lung (sclerosing hemangioma variant?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362113"}
{"pmid": "4362116", "title": "Myopathies in the elderly.", "content": "Myopathies in the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362116"}
{"pmid": "4362117", "title": "Pro-hormones in tissues and in circulation.", "content": "Pro-hormones in tissues and in circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362117"}
{"pmid": "4362119", "title": "Studies on the pituitary \"Fellstoffwechselhormon\". V. The further purification of lipolytic active peptides from hog pituitary glands.", "content": "Studies on the pituitary \"Fellstoffwechselhormon\". V. The further purification of lipolytic active peptides from hog pituitary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362119"}
{"pmid": "4362118", "title": "Inhibitory effects of calcitonin on lipolysis and 47 calcium accumulation in rat adipose tissue in vivo.", "content": "Inhibitory effects of calcitonin on lipolysis and 47 calcium accumulation in rat adipose tissue in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362118"}
{"pmid": "4362120", "title": "Regulation of adenylate cyclase and cyclic-AMP dependent protein kinase activities in A2-cell rich guinea-pig islets of Langerhans.", "content": "Regulation of adenylate cyclase and cyclic-AMP dependent protein kinase activities in A2-cell rich guinea-pig islets of Langerhans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362120"}
{"pmid": "4362122", "title": "Effect of irreversible adsorbents on the dissociation of the antigen-antibody complexes.", "content": "Effect of irreversible adsorbents on the dissociation of the antigen-antibody complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362122"}
{"pmid": "4362121", "title": "Effect of cyclic AMP on ketogenesis in liver homogenates from pancreatectomized-hypophysectomized dogs.", "content": "Effect of cyclic AMP on ketogenesis in liver homogenates from pancreatectomized-hypophysectomized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362121"}
{"pmid": "4362123", "title": "Human medullary thyroid carcinoma: control of calcitonin secretion in vivo and in tissue culture.", "content": "Human medullary thyroid carcinoma: control of calcitonin secretion in vivo and in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362123"}
{"pmid": "4362124", "title": "Population genetic studies of red cell enzyme polymorphisms in four Spansih populations.", "content": "Population genetic studies of red cell enzyme polymorphisms in four Spansih populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362124"}
{"pmid": "4362125", "title": "Immunology of Ascaris suum infection. I. Production of reaginic antibodies to worm components in rats.", "content": "Immunology of Ascaris suum infection. I. Production of reaginic antibodies to worm components in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362125"}
{"pmid": "4362126", "title": "Heterogeneity of antigen from callus of man.", "content": "Heterogeneity of antigen from callus of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362126"}
{"pmid": "4362128", "title": "Operative culdoscopy ad treatment for the polycystic ovary.", "content": "Operative culdoscopy ad treatment for the polycystic ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362128"}
{"pmid": "4362127", "title": "Artificial insemination. Induced ovulation with intravenous estrogens.", "content": "Artificial insemination. Induced ovulation with intravenous estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362127"}
{"pmid": "4362115", "title": "Bladder dysfunction: a sign of occult colonic carcinoma.", "content": "Bladder dysfunction: a sign of occult colonic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362115"}
{"pmid": "4362114", "title": "Endocavitary irradiation in the curative treatment of early rectal cancers.", "content": "Endocavitary irradiation in the curative treatment of early rectal cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362114"}
{"pmid": "4362129", "title": "Toxic action of anti-H.C.G. antibody to human trophoblast.", "content": "Toxic action of anti-H.C.G. antibody to human trophoblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362129"}
{"pmid": "4362130", "title": "Improved methodology for scanning electron microscopy of the female reproductive tract.", "content": "Improved methodology for scanning electron microscopy of the female reproductive tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362130"}
{"pmid": "4362132", "title": "Autoantibody formation against spermatozoa caused by extravasation of spermatozoa into the interstitium of the epididymis of aged men.", "content": "Autoantibody formation against spermatozoa caused by extravasation of spermatozoa into the interstitium of the epididymis of aged men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362132"}
{"pmid": "4362131", "title": "Etiology and treatment of failed pregnancies.", "content": "Etiology and treatment of failed pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362131"}
{"pmid": "4362134", "title": "Occurrence of embryo mortality in rabbits isoimmunized against semen.", "content": "Occurrence of embryo mortality in rabbits isoimmunized against semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362134"}
{"pmid": "4362133", "title": "Preliminary efforts to capacitate rabbit sperm in vitro.", "content": "Preliminary efforts to capacitate rabbit sperm in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362133"}
{"pmid": "4362135", "title": "Ovarian receptivity to human gonadotropins in primary selective pituitary deficiency in gonadotropins.", "content": "Ovarian receptivity to human gonadotropins in primary selective pituitary deficiency in gonadotropins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362135"}
{"pmid": "4362136", "title": "Evidence for discontinuous replication of circular mitochondrial DNA molecules from Novikoff rat ascites hepatoma cells.", "content": "Evidence for discontinuous replication of circular mitochondrial DNA molecules from Novikoff rat ascites hepatoma cells. Double-forked circular molecules of mitochondrial DNA (mtDNA) from rat tissues, indicated by their form and size to be replicative intermediates, are of two structurally distinct classes. Molecules of the first class are totally double stranded. Molecules of the second class are defined by one daughter segment being totally or partially single stranded. Length histograms of daughter segments measuring between 2% and 44% of the total 5-microm molecular contour were constructed from samples of both classes of replicating molecules derived from mtDNA or Novikoff rat ascites hepatoma cells. For single strand-containing molecules, the lengths fell into eight distinct, reproducible groups with mean values separated by 4.1-7.6% of the circular contour length. For totally double stranded molecules, the lengths fell into seven groups, corresponding to seven of the groups found for single strand-containing molecules. These results suggest that along at least 44% of the contour of mtDNA molecules there exist discrete points at which DNA synthesis tends to be arrested. This may indicate that there are pauses in normal mtDNA synthesis. However, as the DNA used in these experiments was isolated from mitochondrial fractions, the findings may indicate that continuation of synthesis beyond specific points on the nucleotide strands requires a factor which is not available after cell disruption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362136"}
{"pmid": "4362138", "title": "Fusion of erythrocytes and other cells with retention of erythrocyte cytoplasm: nuclear activation in chicken erythrocyte-melanoma heterokaryons.", "content": "Fusion of erythrocytes and other cells with retention of erythrocyte cytoplasm: nuclear activation in chicken erythrocyte-melanoma heterokaryons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362138"}
{"pmid": "4362137", "title": "Ultrastructural localization of cytochrome b5 on rat liver microsomes by means of hybrid antibodies labeled with ferritin.", "content": "Ultrastructural localization of cytochrome b5 on rat liver microsomes by means of hybrid antibodies labeled with ferritin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362137"}
{"pmid": "4362139", "title": "Structural analysis of phosphatidylcholine of plant tissue.", "content": "Structural analysis of phosphatidylcholine of plant tissue. Pure preparations of phosphatidylcholine were isolated from spinach leaf chloroplasts, spinach leaf microsomes, and cauliflower inflorescence. The isolated phosphatidylcholine was treated with snake venom phospholipase A, and the fatty acid distribution and composition of the fatty acid methyl esters prepared from the lysophosphatidylcholine and the freed fatty acid were determined by gas-liquid chromatography. The results showed that saturated fatty acids were preferentially esterified at position 1 and unsaturated fatty acids at position 2. The phosphatidylcholine from cauliflower was also treated with phospholipase C. The resulting diglycerides were fractionated on AgNO(3)-impregnated thin-layer plates. The diglyceride fractions were transesterified and the fatty acid composition of each was determined by gas-liquid chromatography. The predominant species contained linolenic acid only (22% of the total), linolenic and oleic acids (19%), and linolenic and palmitic acids (37%). These molecular species could not be accounted for by random distribution of the fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362139"}
{"pmid": "4362140", "title": "Biosynthesis of phosphatidylcholine by enzyme preparations from spinach leaves.", "content": "Biosynthesis of phosphatidylcholine by enzyme preparations from spinach leaves. The enzymic incorporation of choline-1,2-(14)C from CDP-choline-1,2-(14)C into phosphatidylcholine by spinach leaf preparations was characterized. The enzyme catalyzing the incorporation, choline phosphotransferase, had a pH optimum of about 8.0 and required either Mn(2+) or Mg(2+) as cofactor. The saturation concentration of Mn(2+) was 0.3 mm and that for Mg(2+) was 13 mm. The K(m) for CDP-choline was 10 micro m. The choline phosphotransferase was inhibited by sulfhydryl reagents. The enzyme was inactivated at 30 degrees C, but this inactivation could be prevented by dithiothreitol and Mn(2+). Preincubation of the enzyme with Mn(2+) prevented inhibition by sulfhydryl reagents. The incorporation of diglyceride-U-(14)C into phosphatidylcholine was also studied. The enzyme did not show any diglyceride specificity when exogenous diglyceride was added, indicating that fatty acid distribution in phosphatidylcholine of spinach is not controlled by choline phosphotransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362140"}
{"pmid": "4362141", "title": "Serum lipoprotein accumulation in the livers of orotic acid-fed rats.", "content": "Serum lipoprotein accumulation in the livers of orotic acid-fed rats. This study provides confirmation of previous observations that showed that rats fed a diet containing 1% orotic acid for 7 days develop a fatty liver and that there is an inhibition of the secretion of low density lipoproteins without altering general liver protein synthesis. Accumulated fat droplets (liposomes) are entrapped within rough endoplasmic reticulum vesicles. In this study, these vesicles have been shown to accumulate the apolipoproteins of low and very low density lipoproteins. Inhibition of lipoprotein secretion was demonstrated by perfusion of livers from orotic acid-fed rats with a serum-free medium. Liposomes were isolated from these rats. Partially delipidated liposomes, but not similarly treated microsomes or cell sap, were found to form a precipitation line when reacted against anti-low density lipoprotein antiserum. Detergent solubilization of the liposome followed by density gradient centrifugation resulted in a peak at d 1.025 g/ml containing both lipid and protein. Acrylamide electrophoresis in 8 m urea after total delipidation demonstrated liposomal bands which coelectrophoresed with three of four very low density lipoprotein bands; there was no band corresponding to the very low density lipoprotein band which travels furthest in acrylamide electrophoregrams. However, acrylamide electrophoresis of the apoproteins of serum high density lipoprotein from orotic acid-fed animals revealed the presence of the latter band. The results indicate that liver liposomes from orotic acid-fed rats apparently contain the low density apoprotein and probably several other very low density lipoprotein peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362141"}
{"pmid": "4362142", "title": "A new chromatographic system for vitamin D3 and its metabolites: resoluation of a new vitamin D3 metabolite.", "content": "A new chromatographic system for vitamin D3 and its metabolites: resoluation of a new vitamin D3 metabolite. A simple yet powerful new chromatographic procedure for vitamin D(3) and its metabolites is described. Liquid-gel partition chromatography on Sephadex LH-20 using a solvent of various percentages of CHCl(3) in Skellysolve B (petroleum ether, bp 67-69 degrees C) permits excellent resolution of vitamin D(3), 25-hydroxyvitamin D(3), and their more polar metabolites. Of special importance is the resolution of the metabolites of vitamin D(3) more polar than 25-hydroxycholecalciferol. Because of this resolution, a new metabolite of vitamin D(3) has been demonstrated in the plasma of rats and in the intestines of chicks given 100 IU of vitamin D(3)-1,2-(3)H.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362142"}
{"pmid": "4362143", "title": "Effect of dietary tomatine on cholesterol metabolism in the rat.", "content": "Effect of dietary tomatine on cholesterol metabolism in the rat. Tomatine is a virtually nonabsorbable saponin which has been used as an antifungal agent and analytically as a cholesterol precipitant. It was used in this study to determine whether or not it can form a complex with cholesterol in vivo in the rat intestine and what effects such complex formation would have on cholesterol metabolism. Rats that were fed tomatine as 1% of the diet had a decreased uptake of dietary cholesterol by the liver, an increased rate of hepatic and intestinal cholesterol synthesis as well as a partial offsetting of the dietary cholesterol-induced decrease in hepatic cholesterogenesis, and an apparent increase in sterol excretion without an effect on bile acid excretion. In vitro, tomatine did not sequester cholic acid as did cholestyramine. The results show that tomatine has an effect on cholesterol absorption and on other aspects of lipid metabolism in the rat similar to that of cholestyramine, with the notable exception that tomatine increased sterol excretion while cholestyramine increased bile acid excretion. It was suggested that tomatine forms a nonabsorbable complex with cholesterol in the rat intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362143"}
{"pmid": "4362144", "title": "Synthesis of plasma triglycerides in endogenous hypertriglyceridemia.", "content": "Synthesis of plasma triglycerides in endogenous hypertriglyceridemia. Radioisotopic kinetic studies of triglyceride fatty acid synthesis from serum free fatty acids have been performed in 20 studies of normal and lipemic subjects. The lipemic subjects were characterized as having carbohydrate-responsive endogenous lipemia, and were classified as having either Type III or Type IV prebetalipoproteinemia. In the untreated state, triglyceride production was reduced relative to concentration of triglyceride when compared with the normal control population. In response to carbohydrate restriction an absolute reduction in triglyceride synthesis from free fatty acids was demonstrated. These data indicate that overproduction cannot be importantly implicated as the etiology of this form of endogenous lipemia. The patients thus represent a pathophysiological entity which is distinct from the normal physiological lipemia induced by carbohydrate feeding in which overproduction is reported to be the initiating event.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362144"}
{"pmid": "4362145", "title": "Lipolytic response and adenyl cyclase activity of rat adipocytes as related to cell size.", "content": "Lipolytic response and adenyl cyclase activity of rat adipocytes as related to cell size. The number of fat cells contained in the rat epididymal fat pad was found to increase rapidly as the rats grew to a weight of about 300 g. Additional increases in cell number above this weight were minimal. By contrast, cell size, as measured by the amount of triglyceride per cell, increased linearly until the rats reached about 600 g. Glycerol release per 10(6) cells in response to norepinephrine in vitro was observed to be independent of cell size. Basal release expressed in this manner showed a slight but significant positive correlation with increasing cell size. When the rate of lipolysis was based either on the amount of triglyceride in the incubation medium, as is the usual custom, or on the cell surface area, lipolysis was inversely related to cell size. In addition to these observations on lipolysis, it was also demonstrated that norepinephrine-activated adenyl cyclase activity expressed per 10(6) cells was unaffected by cell size. This leads to the suggestion that the number of adrenergic receptors in the fat cell is fixed and is independent of the size of the cell; as the cell enlarges, these receptors are merely distributed over a greater surface area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362145"}
{"pmid": "4362146", "title": "Chromatography of unusual lipids on thin layers of magnesium oxide.", "content": "Chromatography of unusual lipids on thin layers of magnesium oxide. The chromatographic behavior of some minor components of natural lipids was studied using layers of magnesium oxide and of commercial adsorbents containing magnesium oxide. The lipids investigated included wax esters, cholesteryl esters, diester waxes, and esters, ethers and ether-esters of ethanediol and glycerol. Pronounced differences were found in the patterns of separation of certain lipids on magnesium oxide as compared to silica gel and Florisil. The procedures described afford means for the detection of unusual lipids in natural materials, and their isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362146"}
{"pmid": "4362147", "title": "Resolution of intact phosphatidylinositols by argentation thin-layer chromatography.", "content": "Resolution of intact phosphatidylinositols by argentation thin-layer chromatography. An argentation thin-layer chromatographic method is described for the separation of intact phosphatidylinositols on the basis of the degree of unsaturation of their component fatty acids. The system is applicable for metabolic studies using radioactive precursors of phosphatidylinositol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362147"}
{"pmid": "4362149", "title": "Cytomegalovirus mononucleosis.", "content": "Cytomegalovirus mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362149"}
{"pmid": "4362148", "title": "Proceedings: Gluconeogenesis in fetal and neonatal lambs.", "content": "Proceedings: Gluconeogenesis in fetal and neonatal lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362148"}
{"pmid": "4362154", "title": "Juvenile nasopharyngeal angiofibroma.", "content": "Juvenile nasopharyngeal angiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362154"}
{"pmid": "4362155", "title": "Effect of camptothecin on simian virus 40 DNA.", "content": "Effect of camptothecin on simian virus 40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362155"}
{"pmid": "4362156", "title": "Antibody response and virus survival in cats vaccinated against feline leukaemia.", "content": "Antibody response and virus survival in cats vaccinated against feline leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362156"}
{"pmid": "4362157", "title": "Cyclic GMP response in vivo to cholinergic stimulation of gastric mucosa.", "content": "Cyclic GMP response in vivo to cholinergic stimulation of gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362157"}
{"pmid": "4362158", "title": "Colchicine and vinblastine inhibit fibroblast aggregation.", "content": "Colchicine and vinblastine inhibit fibroblast aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362158"}
{"pmid": "4362161", "title": "Efferent innervation of vestibular and auditory receptors.", "content": "Efferent innervation of vestibular and auditory receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362161"}
{"pmid": "4362162", "title": "Functional significance of connections of the inferior olive.", "content": "Functional significance of connections of the inferior olive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362162"}
{"pmid": "4362164", "title": "Poly I-poly C and endotoxins share immunosuppressive properties and increase the toxicity of alpha-amanitin and hexobarbital.", "content": "Poly I-poly C and endotoxins share immunosuppressive properties and increase the toxicity of alpha-amanitin and hexobarbital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362164"}
{"pmid": "4362165", "title": "Frequent occurrence of hypoplastic optic disks in patients with aniridia.", "content": "Frequent occurrence of hypoplastic optic disks in patients with aniridia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362165"}
{"pmid": "4362166", "title": "The team approach to rehabilitation after mastectomy.", "content": "The team approach to rehabilitation after mastectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362166"}
{"pmid": "4362167", "title": "Letter: A serological survey of parainfluenza type 3 virus infection in pigs in Victoria.", "content": "Letter: A serological survey of parainfluenza type 3 virus infection in pigs in Victoria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362167"}
{"pmid": "4362160", "title": "Alcohol ingestion following intracerebral angiotensin administration and water deprivation.", "content": "Alcohol ingestion following intracerebral angiotensin administration and water deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362160"}
{"pmid": "4362159", "title": "Effects of angiotensin II on central neurons.", "content": "Effects of angiotensin II on central neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362159"}
{"pmid": "4362172", "title": "Respiratory metabolism of tissues in septal forebrain lesioned rats.", "content": "Respiratory metabolism of tissues in septal forebrain lesioned rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362172"}
{"pmid": "4362173", "title": "Comparative studies on the digestive physiology of two sympatric species of Oxyrhachis (Germar) (Membracoidea: Oxyrhachinae) with notes on their taxonomy.", "content": "Comparative studies on the digestive physiology of two sympatric species of Oxyrhachis (Germar) (Membracoidea: Oxyrhachinae) with notes on their taxonomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362173"}
{"pmid": "4362177", "title": "Ovarian neoplasms in children and adolescents.", "content": "Ovarian neoplasms in children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362177"}
{"pmid": "4362178", "title": "Orchioblastoma--a report of two cases.", "content": "Orchioblastoma--a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362178"}
{"pmid": "4362179", "title": "Mixed hepatoblastoma--a case report.", "content": "Mixed hepatoblastoma--a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362179"}
{"pmid": "4362181", "title": "Microflora of fresh and dry-cured hams as affected by fresh ham storage.", "content": "Microflora of fresh and dry-cured hams as affected by fresh ham storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362181"}
{"pmid": "4362180", "title": "Endodermal sinus tumor of ovary--a case report.", "content": "Endodermal sinus tumor of ovary--a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362180"}
{"pmid": "4362182", "title": "Dissociation of plasma and spinal fluid ACTH in Nelson syndrome.", "content": "Dissociation of plasma and spinal fluid ACTH in Nelson syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362182"}
{"pmid": "4362183", "title": "Bilateral aseptic necrosis of femur following a 16-day course of corticotropin.", "content": "Bilateral aseptic necrosis of femur following a 16-day course of corticotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362183"}
{"pmid": "4362186", "title": "Hepatoma--foetal Phe-tRNA also present in normal rat liver.", "content": "Hepatoma--foetal Phe-tRNA also present in normal rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362186"}
{"pmid": "4362188", "title": "Response of mouse melanoma cells to melanocyte stimulating hormone.", "content": "Response of mouse melanoma cells to melanocyte stimulating hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362188"}
{"pmid": "4362187", "title": "Stimulation of calcitonin synthesis and release in vitro by calcium and dibutyryl cyclic AMP.", "content": "Stimulation of calcitonin synthesis and release in vitro by calcium and dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362187"}
{"pmid": "4362189", "title": "Ultrastructural changes of erythrocyte membranes isolated with colloidal silica solution (Ludox).", "content": "Ultrastructural changes of erythrocyte membranes isolated with colloidal silica solution (Ludox).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362189"}
{"pmid": "4362190", "title": "Nocturnal secretory patterns of FSH, GH, LH and TSH.", "content": "Nocturnal secretory patterns of FSH, GH, LH and TSH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362190"}
{"pmid": "4362200", "title": "Ultrastructural study of the pericardial organ-anterior ramifications complex neurosecretory terminals.", "content": "Ultrastructural study of the pericardial organ-anterior ramifications complex neurosecretory terminals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362200"}
{"pmid": "4362201", "title": "Ultrastructure of the sexual segments of the kidney in male and female lizards, Cnemidophorus l. lemniscatus (L.).", "content": "Ultrastructure of the sexual segments of the kidney in male and female lizards, Cnemidophorus l. lemniscatus (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362201"}
{"pmid": "4362203", "title": "Development of muscle spindles deprived of fusimotor innervation.", "content": "Development of muscle spindles deprived of fusimotor innervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362203"}
{"pmid": "4362204", "title": "Ultrastructural changes in the secretory cycle of parathyroid cells of winter frogs (Rana pipiens) after pituitary homoimplantation.", "content": "Ultrastructural changes in the secretory cycle of parathyroid cells of winter frogs (Rana pipiens) after pituitary homoimplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362204"}
{"pmid": "4362205", "title": "Electron microscopic study of the substantia nigra and the strio-nigral projection in the rat.", "content": "Electron microscopic study of the substantia nigra and the strio-nigral projection in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362205"}
{"pmid": "4362207", "title": "Surface morphology of the subfornical organ in the rabbit's brain.", "content": "Surface morphology of the subfornical organ in the rabbit's brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362207"}
{"pmid": "4362206", "title": "Effect of cycloheximide on the fine structure of corpus luteum in intact and hypophysectomized rats.", "content": "Effect of cycloheximide on the fine structure of corpus luteum in intact and hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362206"}
{"pmid": "4362208", "title": "Fine structure of capillaries in the pecten oculi of the sparrow, Passer domesticus.", "content": "Fine structure of capillaries in the pecten oculi of the sparrow, Passer domesticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362208"}
{"pmid": "4362210", "title": "Lysosomal enzymes in neurological and psychiatric conditions.", "content": "Lysosomal enzymes in neurological and psychiatric conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362210"}
{"pmid": "4362209", "title": "Changes in total histamine content of white blood cells (WBC) in allergy patients.", "content": "Changes in total histamine content of white blood cells (WBC) in allergy patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362209"}
{"pmid": "4362211", "title": "Corticosteroids, circulating leukocytes, and erythrocytes in cattle: diurnal changes and effects of bacteriologic status, stage of lactation, and milk yield on response to adrenocorticotropin.", "content": "Corticosteroids, circulating leukocytes, and erythrocytes in cattle: diurnal changes and effects of bacteriologic status, stage of lactation, and milk yield on response to adrenocorticotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362211"}
{"pmid": "4362212", "title": "Multiple viral infection in calves with acute bovine respiratory tract disease.", "content": "Multiple viral infection in calves with acute bovine respiratory tract disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362212"}
{"pmid": "4362213", "title": "Hypolipoidemia and hypergammaglobulinemia associated with experimentally induced anaplasmosis in calves.", "content": "Hypolipoidemia and hypergammaglobulinemia associated with experimentally induced anaplasmosis in calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362213"}
{"pmid": "4362214", "title": "Growth of bovine cell monolayer cultures from tissue explants.", "content": "Growth of bovine cell monolayer cultures from tissue explants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362214"}
{"pmid": "4362215", "title": "A gas chromatographic-mass spectrometric analysis of the esterifying alcohols of pumpkin seed protochlorophylls.", "content": "A gas chromatographic-mass spectrometric analysis of the esterifying alcohols of pumpkin seed protochlorophylls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362215"}
{"pmid": "4362216", "title": "A rapid and sensitive radiometric assay procedure for thiamine pyrophosphokinase activity using anion-exchange paper discs.", "content": "A rapid and sensitive radiometric assay procedure for thiamine pyrophosphokinase activity using anion-exchange paper discs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362216"}
{"pmid": "4362217", "title": "Metal-ion distribution in metalloproteins by proton-induced x-ray emission analysis.", "content": "Metal-ion distribution in metalloproteins by proton-induced x-ray emission analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362217"}
{"pmid": "4362221", "title": "Humoral control of airways.", "content": "Humoral control of airways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362221"}
{"pmid": "4362222", "title": "Induction of the humoral antibody response via the respiratory tract.", "content": "Induction of the humoral antibody response via the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362222"}
{"pmid": "4362223", "title": "Synthesis of polyadenosine diphosphate ribose by isolated nuclei of swine aortic tissue.", "content": "Synthesis of polyadenosine diphosphate ribose by isolated nuclei of swine aortic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362223"}
{"pmid": "4362224", "title": "Interaction of cytochrome c peroxidase with cytochrome c.", "content": "Interaction of cytochrome c peroxidase with cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362224"}
{"pmid": "4362218", "title": "The Epstein-Barr Virus (EBV) in Burkitt's lymphoma and nasopharyngeal carcinoma.", "content": "The Epstein-Barr Virus (EBV) in Burkitt's lymphoma and nasopharyngeal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362218"}
{"pmid": "4362225", "title": "Some properties of a cytochrome c-mixed mitochondrial phospholipid complex.", "content": "Some properties of a cytochrome c-mixed mitochondrial phospholipid complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362225"}
{"pmid": "4362226", "title": "Biosynthesis of head-to-head terpenes. Carbonium ion rearrangements which lead to head-to-head terpenes.", "content": "Biosynthesis of head-to-head terpenes. Carbonium ion rearrangements which lead to head-to-head terpenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362226"}
{"pmid": "4362219", "title": "Molecular basis of cell proliferation: the cell cycle.", "content": "Molecular basis of cell proliferation: the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362219"}
{"pmid": "4362227", "title": "Base-sequence relationships between avian ribonucleic acid endogenous and sarcoma viruses assayed by competitive ribonucleic acid-deoxyribonucleic acid hybridization.", "content": "Base-sequence relationships between avian ribonucleic acid endogenous and sarcoma viruses assayed by competitive ribonucleic acid-deoxyribonucleic acid hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362227"}
{"pmid": "4362230", "title": "The separation and partial purification of the soluble 17 alpha- and 17 beta-hydroxysteroid dehydrogenases of rabbit liver.", "content": "The separation and partial purification of the soluble 17 alpha- and 17 beta-hydroxysteroid dehydrogenases of rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362230"}
{"pmid": "4362229", "title": "Synthesis of peptides with the solid phase method. II. Octapeptide analogues of angiotensin II.", "content": "Synthesis of peptides with the solid phase method. II. Octapeptide analogues of angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362229"}
{"pmid": "4362231", "title": "Adenosine-3',5'-monophosphate-dependent protein kinase from bovine anterior pituitary gland. 3. Structural specificity of the ATP site of the catalytic subunit.", "content": "Adenosine-3',5'-monophosphate-dependent protein kinase from bovine anterior pituitary gland. 3. Structural specificity of the ATP site of the catalytic subunit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362231"}
{"pmid": "4362228", "title": "Synthesis of peptides by the solid phase method. I. Tetradecapeptide renin substrate and intermediate peptides, nonapeptides, and fragments of angiotensin II.", "content": "Synthesis of peptides by the solid phase method. I. Tetradecapeptide renin substrate and intermediate peptides, nonapeptides, and fragments of angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362228"}
{"pmid": "4362232", "title": "Metabolism and transport of purine nucleosides by membrane preparations of Micrococcus sodonensis.", "content": "Metabolism and transport of purine nucleosides by membrane preparations of Micrococcus sodonensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362232"}
{"pmid": "4362234", "title": "Respiratory viral infections among thoroughbred horses in training during 1972.", "content": "Respiratory viral infections among thoroughbred horses in training during 1972.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362234"}
{"pmid": "4362235", "title": "Abnormal property of human mutant hypoxanthine-guanine phosphoribosyltransferase: insensitivity of fibroblast enzyme to stabilization against freezing and thawing by 5-phosphoribosyl-1-pyrophosphate.", "content": "Abnormal property of human mutant hypoxanthine-guanine phosphoribosyltransferase: insensitivity of fibroblast enzyme to stabilization against freezing and thawing by 5-phosphoribosyl-1-pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362235"}
{"pmid": "4362220", "title": "Laboratory aids in the diagnosis of pituitary tumors.", "content": "Laboratory aids in the diagnosis of pituitary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362220"}
{"pmid": "4362240", "title": "Carcinomatous neuromyopathy. 1. Electrophysiological studies. An electrophysiological and immunological study of patients with carcinoma of the lung.", "content": "Carcinomatous neuromyopathy. 1. Electrophysiological studies. An electrophysiological and immunological study of patients with carcinoma of the lung. A high incidence of asymptomatic neuromuscular disease was found. More than half showed EMG evidence of a `myopathy' and of denervation. The commonest syndrome was a neuromyopathy with myopathic units and spontaneous muscle activity, especially fasciculations and nerve fibre loss but with normal or near normal nerve conduction. This is thought to be the result of a neuronal or axonal disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362240"}
{"pmid": "4362241", "title": "Carcinomatous neuromyopathy. 2. Immunological studies. An electrophysiological and immunological study of patients with carcinoma of the lung.", "content": "Carcinomatous neuromyopathy. 2. Immunological studies. An electrophysiological and immunological study of patients with carcinoma of the lung. Significant cellular sensitivity to peripheral nerve antigens was found by MIF assay in 36% of patients with lung cancer (P<0·005) as compared with 62% of patients with peripheral neuropathy without neoplasia. No sensitivity was found in controls or the cancer sub-group without neuromuscular abnormality. The significance of these findings for an immune mechanism is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362241"}
{"pmid": "4362242", "title": "Impulse conduction in multiple sclerosis: a theoretical basis for modification by temperature and pharmacological agents.", "content": "Impulse conduction in multiple sclerosis: a theoretical basis for modification by temperature and pharmacological agents. The simplest model for explaining conduction defects in multiple sclerosis (MS) and other demyelinating diseases assumes that the only abnormality present is loss of myelin. The consequences of such an assumption have been investigated by numerical solution of a well-known set of differential equations describing conduction in a model demyelinated axon. In agreement with clinical findings, we show that this model predicts that the temperature at which conduction block occurs is a steep function of the extent of demyelination, so that small temperature increases may block large numbers of conducting fibres. Decreasing calcium concentration (or increasing pH) is calculated markedly to improve the conduction velocity of conducting demyelinated fibres and will, in addition, restore conduction in blocked fibres. The effects of other pharmacological agents have also been computed. The presence of a demyelinating lesion in a nerve fibre is shown greatly to impair the ability of the fibre to conduct repetitive impulses, conduction failing at much lower frequencies than in normal fibres. These calculations provide some insight into the nature of conduction defects in demyelinated nerve, demonstrate that many clinical features of MS are the expected consequence of loss of myelin and do not require the presence of other defects for their explanation, and provide a useful approach to the search for a symptomatic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362242"}
{"pmid": "4362243", "title": "Voluntary control of arm movement in athetotic patients.", "content": "Voluntary control of arm movement in athetotic patients. Visual tracking tests have been employed to provide a quantitative description of voluntary control of arm movement in a group of patients suffering from athetoid cerebral palsy. Voluntary control was impaired in all patients in a characteristic manner. Maximum velocity and acceleration of arm movement were reduced to about 30-50% of their values in normal subjects and the time lag of the response to a visual stimulus was two or three times greater than in normals. Tracking transmission characteristics indicated a degree of underdamping which was not presnet in normal or spastic patients. This underdamping could be responsible for a low frequency (0·3-0·6 Hz) transient oscillation in elbow-angle movements associated with sudden voluntary movement. The maximum frequency at which patients could produce a coherent tracking response was only 50% of that in normal subjects and the relationship between the electromyogram and muscle contraction indicated that the mechanical load on the biceps muscle was abnormal, possibly due to increased stiffness of joint movement caused by involuntary activity in agonist and antagonist muscles acting across the joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362243"}
{"pmid": "4362245", "title": "Interstitial nephritis in rats immunized with heterologous tubular basement membrane.", "content": "Interstitial nephritis in rats immunized with heterologous tubular basement membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362245"}
{"pmid": "4362244", "title": "Creutzfeldt-Jakob disease: further similarities with kuru.", "content": "Creutzfeldt-Jakob disease: further similarities with kuru. A typical case of Creutzfeldt-Jakob disease is described. Two unusual morphological features-namely, `kuru-like' plaques in the cerebellum and coarsely vacuolated neurones in the striatum-are further similarities between Creutzfeldt-Jakob disease and kuru.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362244"}
{"pmid": "4362247", "title": "Antibodies to common ovine and bovine C-type virus specific antigen in serum from sheep with spontaneous leukosis and from inoculated animals.", "content": "Antibodies to common ovine and bovine C-type virus specific antigen in serum from sheep with spontaneous leukosis and from inoculated animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362247"}
{"pmid": "4362248", "title": "Typing of Herpesvirus simplex hominis 1 and 2 by indirect immunofluorescence.", "content": "Typing of Herpesvirus simplex hominis 1 and 2 by indirect immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362248"}
{"pmid": "4362246", "title": "Vitamin B6 deficiency in uremia and its implications for the depression of immune responses.", "content": "Vitamin B6 deficiency in uremia and its implications for the depression of immune responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362246"}
{"pmid": "4362255", "title": "The isolation of a reovirus-like agent associated with diarrhoea in colostrum-deprived calves in Great Britain.", "content": "The isolation of a reovirus-like agent associated with diarrhoea in colostrum-deprived calves in Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362255"}
{"pmid": "4362257", "title": "Avian adenoviruses: a study of 8 field isolates.", "content": "Avian adenoviruses: a study of 8 field isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362257"}
{"pmid": "4362256", "title": "Changes in ionic composition of allantoic fluid during adrenocorticotrophin infusion into fetal sheep.", "content": "Changes in ionic composition of allantoic fluid during adrenocorticotrophin infusion into fetal sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362256"}
{"pmid": "4362258", "title": "The effect of infectious bronchitis (IB) virus on day-old chicks previously infected as 17-day-old embryos with an avian adenovirus.", "content": "The effect of infectious bronchitis (IB) virus on day-old chicks previously infected as 17-day-old embryos with an avian adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362258"}
{"pmid": "4362266", "title": "Gastrointestinal hormones.", "content": "Gastrointestinal hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362266"}
{"pmid": "4362273", "title": "Radiological appearances of hepatic tumours in Hong Kong.", "content": "Radiological appearances of hepatic tumours in Hong Kong.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362273"}
{"pmid": "4362272", "title": "An electron microscopical study of the cerebral cortex of the calf. II. The calf with amprolium-induced cerebrocortical necrosis.", "content": "An electron microscopical study of the cerebral cortex of the calf. II. The calf with amprolium-induced cerebrocortical necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362272"}
{"pmid": "4362274", "title": "Cross-sensitivities of X-ray and UV-light of two strains of murine lymphoma L5178y cells in vitro.", "content": "Cross-sensitivities of X-ray and UV-light of two strains of murine lymphoma L5178y cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362274"}
{"pmid": "4362276", "title": "Clinical thermography.", "content": "Clinical thermography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362276"}
{"pmid": "4362279", "title": "Amoebiasis and the Entamoeba histolytica.", "content": "Amoebiasis and the Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362279"}
{"pmid": "4362280", "title": "Obstruction of the vasa deferentia of the male rat and rabbit with silastic medical adhesive.", "content": "Obstruction of the vasa deferentia of the male rat and rabbit with silastic medical adhesive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362280"}
{"pmid": "4362281", "title": "Fertility control by continuous administration of d-Norgestrel, 0.03 mg.", "content": "Fertility control by continuous administration of d-Norgestrel, 0.03 mg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362281"}
{"pmid": "4362283", "title": "Oral contraceptives and correlation between serum copper and ceruloplasmin levels.", "content": "Oral contraceptives and correlation between serum copper and ceruloplasmin levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362283"}
{"pmid": "4362282", "title": "Physiology and physiopathology of the fallopian tube.", "content": "Physiology and physiopathology of the fallopian tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362282"}
{"pmid": "4362284", "title": "Effect of vasoligation of 14-day-old and 21-day-old rats on spermatogenesis.", "content": "Effect of vasoligation of 14-day-old and 21-day-old rats on spermatogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362284"}
{"pmid": "4362285", "title": "Tuboplasty for infertility. A review of 100 cases.", "content": "Tuboplasty for infertility. A review of 100 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362285"}
{"pmid": "4362286", "title": "Melatonin action on the time course of compensatory ovarian hypertrophy in the Swiss-Webster mouse.", "content": "Melatonin action on the time course of compensatory ovarian hypertrophy in the Swiss-Webster mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362286"}
{"pmid": "4362289", "title": "The family practice approach to management of illness in the academic setting.", "content": "The family practice approach to management of illness in the academic setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362289"}
{"pmid": "4362291", "title": "Light intensity measurement; characteristics of light sources; filters and monochromators.", "content": "Light intensity measurement; characteristics of light sources; filters and monochromators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362291"}
{"pmid": "4362290", "title": "Two-stage phosphorylation techniques: light-to-dark and acid-to-base procedures.", "content": "Two-stage phosphorylation techniques: light-to-dark and acid-to-base procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362290"}
{"pmid": "4362292", "title": "Enhancement.", "content": "Enhancement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362292"}
{"pmid": "4362293", "title": "Clostridial rubredoxin.", "content": "Clostridial rubredoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362293"}
{"pmid": "4362294", "title": "Purification of nitrogenase and crystallization of its Mo-Fe protein.", "content": "Purification of nitrogenase and crystallization of its Mo-Fe protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362294"}
{"pmid": "4362295", "title": "Techniques for studying light-induced paramagnetism in photosynthetic materials by means of electron paramagnetic resonance spectroscopy.", "content": "Techniques for studying light-induced paramagnetism in photosynthetic materials by means of electron paramagnetic resonance spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362295"}
{"pmid": "4362309", "title": "The treatment of carcinoma of the lung by radiotherapy.", "content": "The treatment of carcinoma of the lung by radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362309"}
{"pmid": "4362308", "title": "Non-surgical treatment of lung cancer--selection of cases for surgery.", "content": "Non-surgical treatment of lung cancer--selection of cases for surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362308"}
{"pmid": "4362320", "title": "A porcine Enterovirus causing fetal death and mummification. I. Characteristics and identification.", "content": "A porcine Enterovirus causing fetal death and mummification. I. Characteristics and identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362320"}
{"pmid": "4362321", "title": "A porcine Enterovirus causing fetal death and mummification. II. Experimental infection of pregnant sows.", "content": "A porcine Enterovirus causing fetal death and mummification. II. Experimental infection of pregnant sows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362321"}
{"pmid": "4362322", "title": "Immunological activity of foot-and-mouth disease virus purified by polyethylene glycol precipitation.", "content": "Immunological activity of foot-and-mouth disease virus purified by polyethylene glycol precipitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362322"}
{"pmid": "4362323", "title": "Studies of the foot-and-mouth disease virus sub-types using antigens inactivated by gamma radiations.", "content": "Studies of the foot-and-mouth disease virus sub-types using antigens inactivated by gamma radiations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362323"}
{"pmid": "4362324", "title": "Some characteristics of the immune response to cytomegalovirus infection.", "content": "Some characteristics of the immune response to cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362324"}
{"pmid": "4362330", "title": "Comparison of the turnover patterns of total and individual muscle proteins in normal mice and those with hereditary muscular dystrophy.", "content": "Comparison of the turnover patterns of total and individual muscle proteins in normal mice and those with hereditary muscular dystrophy. 1. The incorporation of amino acids into hindleg muscle proteins of normal and dystrophic mice was measured (1/2)h to 16 days after administration of the radioactive pulse. 2. Dystrophic animals showed a faster initial rate of incorporation into total and soluble proteins in the first few hours after injection, but the extent of incorporation relative to the size of the amino acid pool was similar in both. There was little difference between the overall degradation rates although this started later in the dystrophic proteins. An initial fast phase of degradation reached a plateau after 3 days whereupon the residual label in the protein remained constant up to 16 days after injection. 3. Analyses of individual radioactive proteins fractionated by polyacrylamide-gel electrophoresis showed that the distribution of label was similar in all the soluble proteins from normal and dystrophic muscle. Time-course experiments revealed that in dystrophic mice the two major soluble proteins of the muscle, creatine kinase and adenylate kinase, initially incorporated 2-3 times more label relative to the initial size of the precursor pool. This label was then lost equally rapidly and the final plateau value was much less than that in normal mice. This initial peak of activity was not observed in normal mice. 4. A group of dehydrogenases showed similar initial turnover patterns in both dystrophic and normal mice but the final plateau value was much higher in the former. 5. The results provide support for the hypothesis that there is no obvious defect in the protein synthetic machinery of dystrophic muscle. However, certain proteins do show anomalous turnover patterns relative to those in normal animals. A single structural gene mutation giving rise to one particularly unstable and readily degradable muscle protein is excluded as the cause of the dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362330"}
{"pmid": "4362332", "title": "Induction of delta-aminolaevulinate synthetase under environmental-stress conditions.", "content": "Induction of delta-aminolaevulinate synthetase under environmental-stress conditions. 1. Exposure of rats to environmental-stress conditions of hypobaria, hypoxia and cold did not alter the activity of hepatic delta-aminolaevulinate synthetase. 2. Induction of the enzyme by diethoxycarbonyldihydrocollidine was inhibited when the rats were exposed to hypobaria before or during the treatment with the drug but not after the initial phase when the process of induction was initiated. Neither increased concentration of the drug nor the time of induction had any effect on the inhibition under hypobaria. 3. A period of 12-24h of pre-exposure to hypobaria gave the maximum inhibition, and on longer exposure the inhibitory effect was decreased. 4. The inhibition was not a permanent effect and could be substantially reversed in 12h of withdrawal to ambient pressure. 5. Inhibition of induction was found under hypobaria and hypoxia, but not on exposure to cold. This suggests a specific effect of lack of O(2) rather than a general effect of stress. 6. It appears possible that alteration of concentration of endogenous adenine nucleotides may control the process of diethoxycarbonyldihydrocollidine-mediated induction of delta-aminolaevulinate synthetase, since treatment with ATP, cyclic AMP or theophylline produced inhibition similar to that under hypobaria and hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362332"}
{"pmid": "4362331", "title": "The metabolism of nitrilotriacetate by a pseudomonad.", "content": "The metabolism of nitrilotriacetate by a pseudomonad. 1. An organism that grows on nitrilotriacetate as sole source of carbon and energy was isolated in pure culture and was identified as a pseudomonad. 2. Cell-free extracts of the nitrilotriacetate-grown pseudomonad contain an enzyme that catalyses the NADH-and O(2)-dependent oxidation of nitrilotriacetate to iminodiacetate and glyoxalate. This enzyme is absent from extracts of glucose-grown cells. 3. Compared with growth on glucose, growth on nitrilotriacetate results in increased activities of enzymes of glycine and serine metabolism, namely serine hydroxymethyltransferase, glycine decarboxylase, serine-oxaloacetate aminotransferase and hydroxypyruvate reductase. 4. Cell-free extracts of the nitrilotriacetate-grown organism contain the enzyme glyoxalate carboligase and, when supplemented with NADH, Mg(2+) and thiamin pyrophosphate, can catalyse the anaerobic conversion of glyoxalate into glycerate. 5. These results are incorporated in a scheme which shows the oxidative metabolism of nitrilotriacetate by the successive removal of C(2) units to form 2mol of glyoxalate and 1mol of glycine per mol of nitrilotriacetate degraded. The glyoxalate and glycine are then both metabolized to glycerate by separate pathways, via tartronic semialdehyde and serine respectively. The role of this scheme in the growth of the organism on nitrilotriacetate is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362331"}
{"pmid": "4362334", "title": "Criteria for identifying a myelin-like fraction from developing brain.", "content": "Criteria for identifying a myelin-like fraction from developing brain. Multiple criteria must be used to relate a membrane fraction (;myelin-like') to myelin. These reported in this communication are electron microscopy, marker enzymes, sodium dodecyl sulphate-polyacrylamide-gel electrophoretic patterns and lipid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362334"}
{"pmid": "4362333", "title": "Progesterone and the metabolic control of the lactose biosynthetic pathway during lactogenesis in the rat.", "content": "Progesterone and the metabolic control of the lactose biosynthetic pathway during lactogenesis in the rat. 1. Lactogenesis was initiated in pregnant rats by ovariectomy, thereby causing progesterone withdrawal, after which the mammary tissue was analysed for contents of enzymes and metabolites concerned with the biosynthesis of lactose. 2. Lactose synthesis increased about 126-fold with little or no accompanying change in the contents of most metabolic intermediates or in the adenine nucleotide energy charge. 3. Comparison of mass-action ratios with equilibrium constants showed that phosphoglucomutase (EC 2.7.5.1), UDP-glucose pyrophosphorylase (EC 2.7.7.9) and UDP-glucose epimerase (EC 5.1.3.2.) catalysed reactions close to equilibrium. Nucleoside diphosphokinase (EC 2.7.4.6.) activity was very high and probably equilibrates the UTP-UDP and ATP-ADP couples. Lactose synthetase and hexokinase (EC 2.7.1.1) appeared to catalyse rate-limiting reactions. 4. Large increases were seen of UDP-glucose pyrophosphorylase (5-fold), lactose synthetase A protein (3.8-fold) and alpha-lactalbumin (28-fold), but not of hexokinase, phosphoglucomutase, UDP-glucose epimerase, nucleoside diphosphokinase or glucose 6-phosphate dehydrogenase (EC 1.1.1.49) activities. 5. It appeared that the increased lactose synthesis was largely accounted for by the increased lactose synthetase A protein activity and alpha-lactalbumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362333"}
{"pmid": "4362335", "title": "The effect of ethylene on (1-14C)glycerol incorporation into phospholipids of etiolated pea stems.", "content": "The effect of ethylene on (1-14C)glycerol incorporation into phospholipids of etiolated pea stems. The effect of ethylene (10 p.p.m.) on the rate of incorporation of [1-(14)C]glycerol into phospholipids of etiolated pea stems was studied. After 2-3h treatment with ethylene, incorporation was decreased by 50%. It remained at this value for as long as ethylene was supplied (8h). Handling the plants also caused a temporary decrease in incorporation, which we attribute to the production of endogenous ;wound' ethylene. The percentage decrease in incorporation was the same in four major phospholipid fractions, i.e. phosphatidylcholine, phosphatidylethanolamine, phosphatidylglycerol and phosphatidylinositol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362335"}
{"pmid": "4362337", "title": "The metabolism of benzene by bacteria. Purification and some properties of the enzyme cis-1,2-dihydroxycyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase (cis-benzene glycol dehydrogenase).", "content": "The metabolism of benzene by bacteria. Purification and some properties of the enzyme cis-1,2-dihydroxycyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase (cis-benzene glycol dehydrogenase). 1. cis-Benzene glycol dehydrogenase was purified to a homogeneous state from a species of Pseudomonas grown with benzene as the major carbon source. 2. The enzyme was specific for the cis-isomer of its substrate and required NAD(+) as hydrogen acceptor. 3. Partial inactivation of the enzyme, which was observed during purification, could be reversed by the addition of Fe(2+) and GSH. 4. A molecular weight of 440000 was calculated from data obtained by sedimentation-velocity and diffusion analysis in the ultracentrifuge. Sodium dodecyl sulphate polyacrylamide-gel electrophoresis indicated a subunit of molecular weight 110000. 5. p-Chloromercuribenzoic acid and 1,10-phenanthroline were shown to inhibit the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362337"}
{"pmid": "4362336", "title": "Output of (14C)adenine nucleotides and their derivatives from cerebral tissues. Tetrodotoxin-resistant and calcium ion-requiring components.", "content": "Output of (14C)adenine nucleotides and their derivatives from cerebral tissues. Tetrodotoxin-resistant and calcium ion-requiring components. 1. Neocortical tissues, exposed briefly to [(14)C]adenine and containing over 98% of their (14)C as adenine nucleotides, when superfused with glucose-bicarbonate salines released about 0.1% of their (14)C content/min to the superfusate. 2. Addition of unlabelled adenosine to the superfusing fluid increased the (14)C output three- to four-fold; half-maximal increase was given by about 40mum-adenosine, and reasons are adduced for considering the activity of adenosine kinase to be a major factor in conditioning the (14)C output. Adenosine similarly increased the enhanced (14)C output caused by electrical excitation of the superfused tissue; it brought about only a small increase in tissue glycolysis. 3. Output of (14)C from the [(14)C]adenine-labelled tissues was increased when Ca(2+) was omitted from the superfusing fluids, but electrical stimulation did not then liberate more (14)C. Nevertheless, such tissues still responded to electrical stimulation by increased glycolysis, and their (14)C output again became susceptible to increase by electrical stimulation when Ca(2+) was restored. 4. The six-fold increase in tissue glycolysis caused by electrical excitation was almost completely inhibited by tetrodotoxin at 0.1mum and above, but this was associated with about 50% inhibition only in the output of (14)C from tissues preincubated with [(14)C]adenine. The (14)C-labelled compounds of which output was most inhibited by tetrodotoxin were adenosine, inosine and hypoxanthine whereas output in a nucleotide fraction was little affected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362336"}
{"pmid": "4362338", "title": "The role of protein kinase activation in the control of steroidogenesis by adrenocorticotrophic hormone in the adrenal cortex.", "content": "The role of protein kinase activation in the control of steroidogenesis by adrenocorticotrophic hormone in the adrenal cortex. A method has been developed for investigation of the effect of adrenocorticotrophic hormone (ACTH) on the state of activation of a cyclic AMP-dependent protein kinase within cells of the adrenal cortex. Enzyme activity was measured in terms of the quantity of (32)P transferred from [gamma-(32)P]ATP to histone under conditions in which bound cyclic AMP did not dissociate from the regulatory subunit of the protein kinase ACTH (1x10(-2)i.u./ml) caused a rapid and complete activation of the cyclic AMP-dependent protein kinase activity within 2min of hormone addition to the isolated cells. In response to a range of ACTH concentrations a sigmoid log dose-response curve for protein kinase activation was obtained, with half-maximal stimulation attained at about 1x10(-3)i.u./ml. However, some low doses of ACTH that elicited a marked (but submaximal) steroidogenic response failed to cause a clear stimulation of protein kinase activity in isolated adrenal cells. Theophylline (2mm) potentiated the effect of ACTH on protein kinase activity. The results implicate an important role for protein kinase in ACTH action on the adrenocortical cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362338"}
{"pmid": "4362342", "title": "Studies in the basic mineralizing system, CaO-P2O5-H2O.", "content": "Studies in the basic mineralizing system, CaO-P2O5-H2O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362342"}
{"pmid": "4362343", "title": "Microchemical studies of acid glycosaminoglycans from isolated chondrocytes in suspension.", "content": "Microchemical studies of acid glycosaminoglycans from isolated chondrocytes in suspension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362343"}
{"pmid": "4362345", "title": "Synthesis of a C-nucleoside analog of the antibiotic cordycepin.", "content": "Synthesis of a C-nucleoside analog of the antibiotic cordycepin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362345"}
{"pmid": "4362344", "title": "Ultrastructure and lysosomal histochemistry of ia rat osteoclasts.", "content": "Ultrastructure and lysosomal histochemistry of ia rat osteoclasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362344"}
{"pmid": "4362347", "title": "Synthesis of 6-O-alpha-L-fucopyranosyl-D-galactose.", "content": "Synthesis of 6-O-alpha-L-fucopyranosyl-D-galactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362347"}
{"pmid": "4362348", "title": "Residential treatment of disturbed children: a study of service delivery.", "content": "Residential treatment of disturbed children: a study of service delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362348"}
{"pmid": "4362350", "title": "Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro.", "content": "Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362350"}
{"pmid": "4362349", "title": "Partial purification of the crowding factor from Carassius auratus and Cyprinus carpio.", "content": "Partial purification of the crowding factor from Carassius auratus and Cyprinus carpio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362349"}
{"pmid": "4362352", "title": "Substituted benzoxazole-benzthiazole-2-thiones: interrelationship between anticonvulsant activity and inhibition of nicotinamide adenine dinucleotide-dependent oxidations and monoamine oxidase.", "content": "Substituted benzoxazole-benzthiazole-2-thiones: interrelationship between anticonvulsant activity and inhibition of nicotinamide adenine dinucleotide-dependent oxidations and monoamine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362352"}
{"pmid": "4362351", "title": "Substituted piperazinoquinazolones: relationship between selective inhibition of nicotinamide adenine dinucleotide-dependent oxidations and anticonvulsant activity.", "content": "Substituted piperazinoquinazolones: relationship between selective inhibition of nicotinamide adenine dinucleotide-dependent oxidations and anticonvulsant activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362351"}
{"pmid": "4362353", "title": "Semisolid oleaginous ointment bases for ophthalmic use.", "content": "Semisolid oleaginous ointment bases for ophthalmic use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362353"}
{"pmid": "4362364", "title": "Nutrition in low-birth-weight infants. II. Repeated intravenous injections of fat emulsion.", "content": "Nutrition in low-birth-weight infants. II. Repeated intravenous injections of fat emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362364"}
{"pmid": "4362365", "title": "Impaired interferon response of children with congenital cytomegalovirus disease.", "content": "Impaired interferon response of children with congenital cytomegalovirus disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362365"}
{"pmid": "4362366", "title": "99mTC-pertechnetate brain scintigraphy in children.", "content": "99mTC-pertechnetate brain scintigraphy in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362366"}
{"pmid": "4362369", "title": "Reiter's syndrome. A review of current status and a hypothesis regarding its pathogenesis.", "content": "Reiter's syndrome. A review of current status and a hypothesis regarding its pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362369"}
{"pmid": "4362370", "title": "The matabolism and control mechanism of human hair follicles.", "content": "The matabolism and control mechanism of human hair follicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362370"}
{"pmid": "4362371", "title": "Histochemical and ultrastructural study of a peculiar form of mucopolysaccharidosis.", "content": "Histochemical and ultrastructural study of a peculiar form of mucopolysaccharidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362371"}
{"pmid": "4362372", "title": "Effects of triethyltin on different ATPases, 5'-nucleotidase and phosphodiesterases in grey and white matter of rabbit brain and their relation with brain edema.", "content": "Effects of triethyltin on different ATPases, 5'-nucleotidase and phosphodiesterases in grey and white matter of rabbit brain and their relation with brain edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362372"}
{"pmid": "4362375", "title": "The HL-A antigens on human spermatozoa.", "content": "The HL-A antigens on human spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362375"}
{"pmid": "4362374", "title": "Viral antibodies and autoantibodies in chronic liver disease.", "content": "Viral antibodies and autoantibodies in chronic liver disease. Our previous observations of highly significant increases in high titre antibodies to measles and rubella in patients with chronic active hepatitis have been extended and it has been shown that these reactions do not occur in other forms of liver disease. Significant increases in antibody titres to cytomegalovirus have also been found in patients with chronic active hepatitis (p<0.001) and alcoholic and primary biliary cirrhosis (p<0.05). Antibody titres to herpes simplex, varicella/zoster, parainfluenza I, and Mycoplasma pneumoniae in all forms of chronic liver disease did not differ from controls. Immunofluorescent autoantibodies were correlated with the viral antibodies and a highly significant correlation with strongly positive antismooth muscle and antinuclear antibodies and measles antibody titres in particular was noted. The possible significance of this correlation is discussed in terms of the hypothesis that the intact liver plays a significant role in the sequestering of antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362374"}
{"pmid": "4362376", "title": "Biological consequences of population control.", "content": "Biological consequences of population control. The mechanisms of the possible biological alterations in the human population as a result of population control are discussed.  Population control is distinguished from population limitation by defining it as actual genetic alteration through manipulation of fertilization.  Population limitation such as the use of contraceptive methods is aimed at simply reducing the size of the population by changing reproductive behavioral patterns.  Major avenues of population control include the freezing of semen for artificial insemination, which causes biochemical changes in the sperm cells and reduces spermatozoa viability in the female reproductive tract.  Artifical fertilizations in infertile couples and prezygotic selection are other actions that can produce genetic alterations in the species.  It is concluded that both deliberate and inadvertent changes in the modes of biological selection as a result of population control and limitation will alter the genetic characteristics of the human population, mainly by reducing genetic  variability.  These possibilities should be considered and watched carefully in population research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362376"}
{"pmid": "4362373", "title": "Studies in alcoholic liver disease in Britain. I. Clinical and pathological patterns related to natural history.", "content": "Studies in alcoholic liver disease in Britain. I. Clinical and pathological patterns related to natural history. A group of 258 patients with various forms of alcoholic liver disease-steatosis, mild and severe hepatitis, and cirrhosis-has been studied. Severity of disease as judged histologically did not correlate very well with clinical presentation although signs of hepatocellular failure were certainly commoner in severe hepatitis and cirrhosis. Fever, pigmentation, and clubbing were also pointers to these two conditions. Alcoholic hepatitis is probably precirrhotic and carries a poor prognosis and the best laboratory indicators of this are moderate elevation of white cell count and bilirubin. Prognosis in alcoholic liver disease is significantly improved by abstinence from alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362373"}
{"pmid": "4362377", "title": "Ovarian pregnancy and the intra-uterine device (IUD). A case report.", "content": "Ovarian pregnancy and the intra-uterine device (IUD). A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362377"}
{"pmid": "4362378", "title": "Preparative separation of rabbit seminal plasma and immunochemical study of the resulting fractions.", "content": "Preparative separation of rabbit seminal plasma and immunochemical study of the resulting fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362378"}
{"pmid": "4362379", "title": "Zinc and magnesium in human spermatozoa.", "content": "Zinc and magnesium in human spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362379"}
{"pmid": "4362380", "title": "Immunobiological studies with the reproductive organs, adrenals and spleen of the female mouse.", "content": "Immunobiological studies with the reproductive organs, adrenals and spleen of the female mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362380"}
{"pmid": "4362381", "title": "Detection of ovulation by color changes in cervical mucus of crab-eating macaque (Macaca fascicularis).", "content": "Detection of ovulation by color changes in cervical mucus of crab-eating macaque (Macaca fascicularis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362381"}
{"pmid": "4362382", "title": "Daily postcoital tests in the conception cycle during treatment of anovulatory women with human gonadotropins.", "content": "Daily postcoital tests in the conception cycle during treatment of anovulatory women with human gonadotropins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362382"}
{"pmid": "4362383", "title": "Treatment of oligospermia by freezing and concentrating semen.", "content": "Treatment of oligospermia by freezing and concentrating semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362383"}
{"pmid": "4362384", "title": "Kymographic utero-tubal insufflation in investigating the mode of action of modern contraceptives.", "content": "Kymographic utero-tubal insufflation in investigating the mode of action of modern contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362384"}
{"pmid": "4362386", "title": "Liver studies during oral contraception with low doses of megestrol acetate.", "content": "Liver studies during oral contraception with low doses of megestrol acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362386"}
{"pmid": "4362385", "title": "Free amino acids in uterine and blastocoelic fluids in the rabbit as affected by ovarian steroids.", "content": "Free amino acids in uterine and blastocoelic fluids in the rabbit as affected by ovarian steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362385"}
{"pmid": "4362387", "title": "A simple method for measuring crystallization of the cervical mucus and its application in human sperm migration.", "content": "A simple method for measuring crystallization of the cervical mucus and its application in human sperm migration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362387"}
{"pmid": "4362388", "title": "Medroxyprogesterone acetate as a contraceptive.", "content": "Medroxyprogesterone acetate as a contraceptive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362388"}
{"pmid": "4362390", "title": "The use of CO2 in the uterine cavity for hysteroscopy.", "content": "The use of CO2 in the uterine cavity for hysteroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362390"}
{"pmid": "4362389", "title": "Medroxyprogesterone acetate (MPA) for contraception.", "content": "Medroxyprogesterone acetate (MPA) for contraception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362389"}
{"pmid": "4362391", "title": "Radiation damage to proteins: the effect of ultra-violet illumination on the secondary radical reactions in a single crystal of glycyl-glycine.", "content": "Radiation damage to proteins: the effect of ultra-violet illumination on the secondary radical reactions in a single crystal of glycyl-glycine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362391"}
{"pmid": "4362392", "title": "Letter: Radiation chemistry of DNA model compounds. IV. Phosphate ester cleavage in radicals derived from glycerol phosphates.", "content": "Letter: Radiation chemistry of DNA model compounds. IV. Phosphate ester cleavage in radicals derived from glycerol phosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362392"}
{"pmid": "4362393", "title": "The human lymphocyte: a model for the study of insulin-receptor interaction.", "content": "The human lymphocyte: a model for the study of insulin-receptor interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362393"}
{"pmid": "4362394", "title": "An FSH-producing pituitary tumor in a patient with hypogonadism.", "content": "An FSH-producing pituitary tumor in a patient with hypogonadism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362394"}
{"pmid": "4362395", "title": "Prolactin and growth hormone in patients with pituitary adenomas: a correlative study of hormone in tumor and plasma by immunoperoxidase technique and radioimmunoassay.", "content": "Prolactin and growth hormone in patients with pituitary adenomas: a correlative study of hormone in tumor and plasma by immunoperoxidase technique and radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362395"}
{"pmid": "4362397", "title": "Diurnal plasma testosterone rhythm and the effects of short-term ACTH administration on plasma testosterone in man.", "content": "Diurnal plasma testosterone rhythm and the effects of short-term ACTH administration on plasma testosterone in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362397"}
{"pmid": "4362396", "title": "Immunoreactive ACTH in cerebrospinal fluid.", "content": "Immunoreactive ACTH in cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362396"}
{"pmid": "4362398", "title": "Relation of sleep-entrained human prolactin release to REM-nonREM cycles.", "content": "Relation of sleep-entrained human prolactin release to REM-nonREM cycles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362398"}
{"pmid": "4362399", "title": "Low affinity binding of thyroxine to proteins of human serum.", "content": "Low affinity binding of thyroxine to proteins of human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362399"}
{"pmid": "4362400", "title": "ACTH-induced sodium retention in pregnancy. Role of desoxycorticosterone and corticosterone.", "content": "ACTH-induced sodium retention in pregnancy. Role of desoxycorticosterone and corticosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362400"}
{"pmid": "4362401", "title": "Herpes simplex virus-specific polypeptides studied by polyacrylamide gel electrophoresis of immune precipitates.", "content": "Herpes simplex virus-specific polypeptides studied by polyacrylamide gel electrophoresis of immune precipitates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362401"}
{"pmid": "4362402", "title": "Close linkage between genetic loci controlling response of fowl to subgroup A and subgroup C sarcoma viruses.", "content": "Close linkage between genetic loci controlling response of fowl to subgroup A and subgroup C sarcoma viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362402"}
{"pmid": "4362403", "title": "Absence of adenovirus-specific repressor in adenovirus tumour cells.", "content": "Absence of adenovirus-specific repressor in adenovirus tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362403"}
{"pmid": "4362404", "title": "Effects of adsorption of u.v.-inactivated parainfluenza (Sendai) virus on the incorporation of amino acids in animal host cells.", "content": "Effects of adsorption of u.v.-inactivated parainfluenza (Sendai) virus on the incorporation of amino acids in animal host cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362404"}
{"pmid": "4362405", "title": "Ferritin-labelled antibody study of RD-114 virus.", "content": "Ferritin-labelled antibody study of RD-114 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362405"}
{"pmid": "4362406", "title": "The detection of foot-and mouth disease virus antigens in infected cell cultures by immuno-peroxidase techniques.", "content": "The detection of foot-and mouth disease virus antigens in infected cell cultures by immuno-peroxidase techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362406"}
{"pmid": "4362407", "title": "Purification of herpes simplex virus.", "content": "Purification of herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362407"}
{"pmid": "4362408", "title": "Studies on the lysosomes of L132 cells infected with either rhinovirus type 2 or poliovirus type 1.", "content": "Studies on the lysosomes of L132 cells infected with either rhinovirus type 2 or poliovirus type 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362408"}
{"pmid": "4362409", "title": "Isolation of a virus responsible for an outbreak of acute haemorrhagic conjunctivitis in Morocco.", "content": "Isolation of a virus responsible for an outbreak of acute haemorrhagic conjunctivitis in Morocco. An epidemic of acute haemorrhagic conjunctivitis occurred in Morocco in 1970-1. It was caused by an enterovirus which appeared to be a new antigenic type similar to a virus isolated in South East Asia during the same period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362409"}
{"pmid": "4362412", "title": "Differentiation of smallpox and camelpox viruses in cultures of human and monkey cells.", "content": "Differentiation of smallpox and camelpox viruses in cultures of human and monkey cells. The cytopathic effect of smallpox and camelpox viruses has been compared in cell cultures derived from human and monkey tissues. The two viruses could easily be distinguished in HeLa, GMK-AH1, BSC-1 and WISH cells, camelpox producing multinucleate giant cells and smallpox producing rounding up of individual cells. In other cells (LLC-MK2, HEK and 2RhK) the differences were not so marked, and in some (VERO, HEL, K and HuTh) no differences were seen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362412"}
{"pmid": "4362411", "title": "Serological evidence of infection with Tana and Yaba pox viruses among several species of monkey.", "content": "Serological evidence of infection with Tana and Yaba pox viruses among several species of monkey. Sera from cynomolgus monkeys from Malaysia, from Indian rhesus monkeys, from various species of monkeys from Africa and from South America have been examined for neutralizing antibody to Tanapox and Yaba viruses. No antibody was found to either virus in the sera of rhesus monkeys or South American monkeys. A certain proportion of sera from cynomolgus monkeys and various species of African monkey showed antibody to one or other of the viruses, but few of the positive sera showed antibody to both. The results would seem to suggest that infection with the two viruses is endemic in African and Malaysian monkeys but does not occur or is very rare in Indian rhesus and New World monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362411"}
{"pmid": "4362410", "title": "Experimental pertussis infection in the marmoset: type specificity of active immunity.", "content": "Experimental pertussis infection in the marmoset: type specificity of active immunity. ALTHOUGH WE HAVE FAILED TO PRODUCE EITHER PAROXYSMAL COUGH OR VOMITING IN RHESUS MONKEYS, CYNOMOLGUS MONKEYS AND MARMOSETS, WE HAVE FOUND IN MARMOSETS SEVERAL FEATURES OF PERTUSSIS INFECTION SIMILAR TO THOSE SEEN IN CHILDREN WITH WHOOPING COUGH: catarrh, persistence of colonization of the naso-pharynx with Bordetella pertussis for 4-11 weeks, change of serotype during colonization and inability of type 1 organisms to establish themselves as the predominant serotype.As in children, we have found that intramuscular vaccine of type 1,2,3 was more effective than type 1,2 in preventing persistent infection with the currently prevalent serotypes 1,2,3 and 1,3. A mixed vaccine (1,2,3 and 1,3) seemed to produce agglutinin 3 in the serum more consistently than a pure type 1,2,3 vaccine. The duration of colonization, after naso-pharyngeal challenge, was greatly reduced in animals with agglutinin 3.Local immunity, resulting from previous infection, was even more effective than a good vaccine in preventing subsequent persistent colonization. Marmosets may be useful in studying the possible development of aerosol pertussis vaccine for human use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362410"}
{"pmid": "4362413", "title": "Virus isolations from patients in general practice, 1961-71.", "content": "Virus isolations from patients in general practice, 1961-71. During the period 1961-71 of 1785 viruses isolated from patients in the general population 503 (28%) were rhinoviruses, 465 (26%) influenza viruses, 248 (14%) enteroviruses, 234 (13%) herpes simplex virus, 132 (7%) parainfluenza viruses, 129 (7%) adenoviruses and 49 (3%) respiratory syncytial virus. Also isolated were 18 strains of mumps virus, 7 coronaviruses and 295 streptococci of groups A, C or G.Fluctuations were observed in the frequency with which respiratory syncytial virus, parainfluenza virus type 2, and the adenoviruses were isolated over the 10-year period.Influenza viruses types A and B, parainfluenza viruses types 1 and 2, respiratory syncytial virus, adenoviruses types 3, 4, 6, 7 and 21, and many enteroviruses were all associated with outbreaks.Infections with influenza viruses A and B and parainfluenza viruses types 1 and 2 came during the winter, whereas those with parainfluenza virus type 3, enteroviruses, and rhinoviruses were more frequently seen in the summer and early autumn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362413"}
{"pmid": "4362415", "title": "Immunocytochemical localization of collagenase in human skin and fibroblasts in monolayer culture.", "content": "Immunocytochemical localization of collagenase in human skin and fibroblasts in monolayer culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362415"}
{"pmid": "4362414", "title": "The distribution in Kenya of bluetongue virus and antibody, and the Culicoides vector.", "content": "The distribution in Kenya of bluetongue virus and antibody, and the Culicoides vector. Sera from domestic cattle, sheep and goats and 11 wild bovid species taken at 41 locations throughout Kenya were screened for antibody to bluetongue virus using the indirect fluorescent antibody method. Positive sera were found at 39 locations and in all the species tested. The distribution of clinical disease was mapped and found to be more restricted than the distribution of antibody. Culicoides were collected in light traps at 55 locations throughout Kenya. The presumptive vector of bluetongue in Kenya, C. pallidipennis, was the most widespread species, found in 38 locations. Both the distribution of antibody and Culicoides have been tabulated by ecological zones to demonstrate that bluetongue virus in its natural state in cattle and wild bovids is far more widespread than clinical bluetongue disease seen in exotic sheep of restricted distribution; and that C. pallidipennis has great ecological range.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362414"}
{"pmid": "4362416", "title": "Mitotic response of normal and psoriatic keratinocytes in vitro to compounds known to affect intracellular cyclic AMP.", "content": "Mitotic response of normal and psoriatic keratinocytes in vitro to compounds known to affect intracellular cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362416"}
{"pmid": "4362417", "title": "Letter: Cyclic AMP for psoriasis.", "content": "Letter: Cyclic AMP for psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362417"}
{"pmid": "4362418", "title": "Chemical diagnosis of fetal malnutrition.", "content": "Chemical diagnosis of fetal malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362418"}
{"pmid": "4362419", "title": "Prostaglandins and lipolysis in rat adipose tissue.", "content": "Prostaglandins and lipolysis in rat adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362419"}
{"pmid": "4362423", "title": "Monolayer culture of normal adult and neoplastic cells of the rat and human adrenal cortex.", "content": "Monolayer culture of normal adult and neoplastic cells of the rat and human adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362423"}
{"pmid": "4362424", "title": "Breast thermography--the mammatherm.", "content": "Breast thermography--the mammatherm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362424"}
{"pmid": "4362426", "title": "Angiography of selected pathologic pregnancies.", "content": "Angiography of selected pathologic pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362426"}
{"pmid": "4362427", "title": "The polypeptide composition of mouse mammary tumor virus.", "content": "The polypeptide composition of mouse mammary tumor virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362427"}
{"pmid": "4362425", "title": "Mammography.", "content": "Mammography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362425"}
{"pmid": "4362428", "title": "Relative locations of rearrangements in the DNA of defective simian virus 40 (SV40).", "content": "Relative locations of rearrangements in the DNA of defective simian virus 40 (SV40).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362428"}
{"pmid": "4362429", "title": "Genetic control of expression of endogenous virus genes in chicken cells.", "content": "Genetic control of expression of endogenous virus genes in chicken cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362429"}
{"pmid": "4362430", "title": "Inhibition of avian sarcoma virus replication by glucosamine.", "content": "Inhibition of avian sarcoma virus replication by glucosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362430"}
{"pmid": "4362431", "title": "Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid.", "content": "Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3-dehydro-N-acetylneuraminic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362431"}
{"pmid": "4362432", "title": "Replication of avian sarcoma viruses in chicken macrophages.", "content": "Replication of avian sarcoma viruses in chicken macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362432"}
{"pmid": "4362433", "title": "Analysis of RNA associated with the poliovirus RNA replication complexes.", "content": "Analysis of RNA associated with the poliovirus RNA replication complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362433"}
{"pmid": "4362435", "title": "Electron microscopic observations on early events of frog virus 3 replication.", "content": "Electron microscopic observations on early events of frog virus 3 replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362435"}
{"pmid": "4362434", "title": "Homologies among the nucleotide sequences of the genomes of C-type viruses.", "content": "Homologies among the nucleotide sequences of the genomes of C-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362434"}
{"pmid": "4362437", "title": "Replication of a temperature sensitive mutant of simian virus 40 in normal and SV40-transformed monkey cells.", "content": "Replication of a temperature sensitive mutant of simian virus 40 in normal and SV40-transformed monkey cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362437"}
{"pmid": "4362436", "title": "Sialidase activity of oncogenic cells transformed by herpes simplex virus.", "content": "Sialidase activity of oncogenic cells transformed by herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362436"}
{"pmid": "4362438", "title": "Synthesis of SV40 capsid antigen(s) in heterokaryocytes formed by fusion of nonpermissive with permissive cells.", "content": "Synthesis of SV40 capsid antigen(s) in heterokaryocytes formed by fusion of nonpermissive with permissive cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362438"}
{"pmid": "4362445", "title": "Editorial: Calcium responses (\"calcium spikes\").", "content": "Editorial: Calcium responses (\"calcium spikes\").", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362445"}
{"pmid": "4362446", "title": "Management of vulvar malignancies.", "content": "Management of vulvar malignancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362446"}
{"pmid": "4362447", "title": "The reticular activating system revisited.", "content": "The reticular activating system revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362447"}
{"pmid": "4362448", "title": "Differentiation between the embryonic and tumour specific antigens on chemically induced rat tumours.", "content": "Differentiation between the embryonic and tumour specific antigens on chemically induced rat tumours. The tumour specific antigens and tumour associated embryonic antigens expressed on chemically induced rat hepatomata and sarcomata have been shown to be different by means of blocking antibody studies. Serum from multiparous female rats contained blocking antibody which protected both tumour and embryo cells from the in vitro cytotoxic effect of lymph node cells from multiparous donors. These sera did not, however, block the cytotoxicity of lymph node cells from tumour immune rats for cells of the immunizing tumour. In addition, the tumour specific rejection antigens and embryonic antigens have been shown to have dissimilar locations in tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362448"}
{"pmid": "4362450", "title": "Proceedings: A new look at the EB virus and oncogenesis.", "content": "Proceedings: A new look at the EB virus and oncogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362450"}
{"pmid": "4362451", "title": "Letter: Oral ulceration and infective agents.", "content": "Letter: Oral ulceration and infective agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362451"}
{"pmid": "4362449", "title": "Additive effect in the induction of kidney tumours in rats treated with dimethylnitrosamine and ethylmethanesulphonate.", "content": "Additive effect in the induction of kidney tumours in rats treated with dimethylnitrosamine and ethylmethanesulphonate. Wistar rats were treated with a single dose of 30 mg/kg of DMN or with single doses of 100, 200 or 300 mg/kg of EMS. Tumours of the kidney developed in a few animals receiving EMS and in 33% of the male and 63% of the female rats treated with DMN alone. In the animals receiving DMN and, 8 hours later, a single dose of 100, 200 or 300 mg/kg of EMS, an additive effect was observed in the induction of kidney tumours. This additive effect was more pronounced in female than in male rats. Morphologically, the tumours were of epithelial and mesenchymal type with a preponderance of the former type. The significance of alkylation of the nucleic acids of the kidney observed with these two compounds is discussed in relation to the present findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362449"}
{"pmid": "4362453", "title": "Letter: Poliomyelitis after contact with recently vaccinated infant.", "content": "Letter: Poliomyelitis after contact with recently vaccinated infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362453"}
{"pmid": "4362454", "title": "Letter: Serological tests for amoebiasis.", "content": "Letter: Serological tests for amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362454"}
{"pmid": "4362452", "title": "Excess deoxycorticosterone secretion from adrenocortical carcinoma.", "content": "Excess deoxycorticosterone secretion from adrenocortical carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362452"}
{"pmid": "4362455", "title": "Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases.", "content": "Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases. The synthetic non-steroidal antioestrogen nafoxidine (U-11, 100A) was given by mouth to 52 women with locally advanced or metastatic breast cancer, in 85% of whom the disease had become resistant to, or relapsed after, previous endocrine treatment. The objective response rate (complete or partial regression of disease) among 48 cases treated for at least four weeks was 37%. Tumours in soft tissue seemed to respond better than skeletal metastases. The patients in all but one of the 52 cases were postmenopausal. Those who had had an objective response to previous hormone treatment had a greater chance of deriving benefit from nafoxidine than those who had been resistant to hormone treatment.Side effects of nafoxidine were dryness of skin, increased loss of scalp hair, and heightened sensitivity to sunlight. None were serious, and they could be lessened by protection from solar radiation or a decrease in dosage. No obvious depression of thyroid or adrenal function or obvious water retention or masculinization was seen. Cataract was a possible complication.This clinical trial was preceded by laboratory studies in which a transplantable oestrogen-dependent tumour in the Syrian hamster was notably inhibited by the administration of nafoxidine. This experimental model may prove useful in screening potentially useful antioestrogenic agents against breast cancer before a human trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362455"}
{"pmid": "4362458", "title": "Formation of estrogen glucosiduronates by human kidney homogenates.", "content": "Formation of estrogen glucosiduronates by human kidney homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362458"}
{"pmid": "4362456", "title": "Central effects of beta-(para-chlorophenyl)-gamma-aminobutyric acid.", "content": "Central effects of beta-(para-chlorophenyl)-gamma-aminobutyric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362456"}
{"pmid": "4362457", "title": "Properties of P503 (prototetrahydroporphyrin IC) in cells and extracts of Saccharomyces cerevisiae.", "content": "Properties of P503 (prototetrahydroporphyrin IC) in cells and extracts of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362457"}
{"pmid": "4362459", "title": "Letter: Barium suspension versus water-soluble, iodinated compounds in diagnostic radiology of the upper gastrointestinal tract.", "content": "Letter: Barium suspension versus water-soluble, iodinated compounds in diagnostic radiology of the upper gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362459"}
{"pmid": "4362460", "title": "Xeroradiography of the breast.", "content": "Xeroradiography of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362460"}
{"pmid": "4362461", "title": "Cytochemical localization of polysaccharides in Claviceps paspali ultrastructure during submerged fermentation of alkaloids.", "content": "Cytochemical localization of polysaccharides in Claviceps paspali ultrastructure during submerged fermentation of alkaloids. Morphological characteristics of two types of elements in the submerged mycelium of Claviceps paspali are described. Distribution of polysaccharides in the cell wall and cytoplasm was cytochemically determined at the ultrastructural level. Polysaccharide deposition into the cell walls was proportional to the increase in the alkaloid yield. In the cytoplasm, on the other hand, the presence of polysaccharide grains indicated an absence of alkaloid synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362461"}
{"pmid": "4362462", "title": "Bioassay for the isolation of Dictyostelium discoideum mutants deficient in extracellular accumulation of cyclic adenosine 3',5'-monophosphate.", "content": "Bioassay for the isolation of Dictyostelium discoideum mutants deficient in extracellular accumulation of cyclic adenosine 3',5'-monophosphate. The growth response to external cyclic adenosine 3',5'-monophosphate of a strain of Escherichia coli deleted for adenyl cyclase was utilized to screen for mutants of Dictyostelium discoideum unable to accumulate this chemical extracellularly. The threshold amount of cyclic adenosine 3',5'-monophosphate able to induce growth of this bacterium was 3 to 4 mug/ml at 37 C and approximately 25 mug/ml at 27 C. Conditions are described that permit the detection of as low as 2 mug of this chemical at either temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362462"}
{"pmid": "4362463", "title": "Examination of isolated yeast cell vacuoles for active transport.", "content": "Examination of isolated yeast cell vacuoles for active transport. Isolated vacuoles of the yeast Candida utilis did not show active transport of S-adenosylmethionine, uric acid, and several amino acids which they concentrate in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362463"}
{"pmid": "4362464", "title": "Microtubule assembly and function in Chlamydomonas: inhibition of growth and flagellar regeneration by antitubulins and other drugs and isolation of resistant mutants.", "content": "Microtubule assembly and function in Chlamydomonas: inhibition of growth and flagellar regeneration by antitubulins and other drugs and isolation of resistant mutants. The distribution of microtubules in Chlamydomonas reinhardtii suggests that they are involved in mitosis, cell and nuclear cleavage, and generation of flagella. Vinblastine, colchicine, and podophyllotoxin bind to the protein building block of microtubules (tubulin) and prevent normal assembly. Mutants resistant to these \"antitubulin\" drugs are candidates to have alterations in tubulin primary structure. We report the ability to inhibit growth, and flagellar regeneration after amputation, of: vinblastine, several colchicine derivatives, two water-soluble derivatives of podophyllotoxin (succinylpodophyllotoxin and epipodophyllotoxin thiuronium bromide), and other substances which may interfere with flagellar assembly or motility (isopropyl N-phenyl carbamate, 2-methoxy-5-nitrotropone, chloral hydrate, caffeine, and nickel acetate). The ability of each drug to inhibit binding of labeled colchicine or podophyllotoxin to mammalian brain tubulin was also determined. The results suggest that only in the cases of colchicine, colcemide, and epipodophyllotoxin thiruonium bromide was the toxicity to Chlamydomonas mediated by inhibition of tubulin assembly. The requirement for high concentrations of colchicine may be due to permeability barriers, since colchicine toxicity was potentiated by deoxycholate. Mutants resistant to antitubulins were isolated after treatment with methyl methanesulfonate. The results with vinblastine were equivocal. Of three mutants resistant to inhibition of growth and flagellar regeneration by colchicine, one was also cross-resistant to epipodophyllotoxin thiuronium bromide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362464"}
{"pmid": "4362465", "title": "Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide-dependent enzyme from Saccharomyces cerevisiae.", "content": "Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide-dependent enzyme from Saccharomyces cerevisiae. A reduced nicotinamide adenine dinucleotide (NADH)-dependent glutamate synthase has been detected and partially purified from crude extracts of Saccharomyces cerevisiae. The enzyme is specific for NADH, glutamine, and alpha-ketoglutarate (K(m) values of 2.6 muM, 1.0 mM, and 140 muM, respectively) and has a pH optimum between 7.1 and 7.7. The stoichiometry of the reaction has been determined as 2 mol of glutamate synthesized per mol of glutamine consumed. Glutamate synthase can be distinguished from either of the glutamate dehydrogenases of yeast on the basis of its substrate requirements and behavior during agarose gel and ion exchange chromatography. Variations in the specific activity of glutamate synthase, which occur in response to changes in the growth medium, are similar in character to those observed with the nicotinamide adenine dinucleotide phosphate-dependent (anabolic) glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362465"}
{"pmid": "4362466", "title": "Inactivation of isocitrate lyase during myxospore development in Myxococcus xanthus.", "content": "Inactivation of isocitrate lyase during myxospore development in Myxococcus xanthus. The inactivation of isocitrate lyase which occurs during late stages of myxospore formation in Myxococcus xanthus was studied. Several findings are reported. (i) Protein synthesis is required over a specific time interval in order for isocitrate lyase inactivation to occur at a later time. (ii) Metabolic energy is required at all times during myxospore development if the inactivation is to occur. (iii) It was possible to inhibit protein turnover to a considerable extent without affecting the net loss in isocitrate lyase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362466"}
{"pmid": "4362468", "title": "Editorial: The pathogenesis of congenital malformations.", "content": "Editorial: The pathogenesis of congenital malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362468"}
{"pmid": "4362467", "title": "Busulfan lung complicated by pneumocystis carinii and cytomegalovirus infection.", "content": "Busulfan lung complicated by pneumocystis carinii and cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362467"}
{"pmid": "4362469", "title": "Congenital choroido-retinitis and cerebral damage from unidentified infective agents.", "content": "Congenital choroido-retinitis and cerebral damage from unidentified infective agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362469"}
{"pmid": "4362471", "title": "The influence of the three color vision-mechanisms on the spectral sensitivity of the fovea.", "content": "The influence of the three color vision-mechanisms on the spectral sensitivity of the fovea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362471"}
{"pmid": "4362470", "title": "The dyschromatopsia of pernicious anaemia.", "content": "The dyschromatopsia of pernicious anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362470"}
{"pmid": "4362472", "title": "An analysis of colour vision in 314 patients.", "content": "An analysis of colour vision in 314 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362472"}
{"pmid": "4362473", "title": "Ectopic secretion of calcitonin by oat-cell carcinoma.", "content": "Ectopic secretion of calcitonin by oat-cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362473"}
{"pmid": "4362474", "title": "Regulation of the circulation. I.", "content": "Regulation of the circulation. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362474"}
{"pmid": "4362475", "title": "Ultrasonic visualization of the uterus, breast and eye by grey scale echography.", "content": "Ultrasonic visualization of the uterus, breast and eye by grey scale echography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362475"}
{"pmid": "4362476", "title": "Radioreceptor assay of human chorionic gonadotropin: detection of early pregnancy.", "content": "Radioreceptor assay of human chorionic gonadotropin: detection of early pregnancy. A rapid, sensitive, and specific radioreceptor assay for the determination of human chorionic gonadotropin and luteinizing hormone in plasma is described. Plasma membranes of bovine corpora lutea of early pregnancy, which bind biologically active labeled human chorionic gonadotropin, have been used as receptor. Pregnancy could be detected by assaying the gonadotropin in plasma samples obtained from day 6 to 8 after conception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362476"}
{"pmid": "4362477", "title": "Partition of tissue functions in epithelia: localization of enzymes in \"mitochondria-rich\" cells of toad urinary bladder.", "content": "Partition of tissue functions in epithelia: localization of enzymes in \"mitochondria-rich\" cells of toad urinary bladder. The mucosal epithelium of the toad urinary bladder reabsorbs sodium, acidifies the urine, and is responsive to neurohypophyseal hormnones. Mucosal epithelial cells, consisting of two major morphologic cell types, \"mitochondria-rich\" and \"granular,\" were removed from the bladder and separated by density gradient centrifugation. The mitochondria-rich cells contained three times as much carbonic anhydrase activity as the granular cells. Oxytocin caused a 235 percent increase in the adenosine 3',5'-monophosphate content of mitochondria-rich cells but had no effect on the granular cells. The evidence indicates that the mitochondria-rich cell, which accounts for only 15 percent of the mucosal cells, plays a major role in the mediation of sodium ion and hydrogen ion transport in the toad bladder and is a specific site of action of neurohypophyseal hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362477"}
{"pmid": "4362480", "title": "Amoebiasis.", "content": "Amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362480"}
{"pmid": "4362482", "title": "The peripheral nerve function in chronic renal failure. 8. Recovery after renal transplantation. Clinical aspects.", "content": "The peripheral nerve function in chronic renal failure. 8. Recovery after renal transplantation. Clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362482"}
{"pmid": "4362484", "title": "Editorial: \"Early to bed\" or sleep revisited.", "content": "Editorial: \"Early to bed\" or sleep revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362484"}
{"pmid": "4362483", "title": "The effect of soya lecithin on serum lipid values in type II hyperlipoproteinemia.", "content": "The effect of soya lecithin on serum lipid values in type II hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362483"}
{"pmid": "4362486", "title": "Parainfluenza virus II and the immunocompromised host.", "content": "Parainfluenza virus II and the immunocompromised host.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362486"}
{"pmid": "4362485", "title": "Doxorubicin in treatment of malignant solid tumors in children.", "content": "Doxorubicin in treatment of malignant solid tumors in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362485"}
{"pmid": "4362487", "title": "Cystosarcoma phyllodes of the breast.", "content": "Cystosarcoma phyllodes of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362487"}
{"pmid": "4362488", "title": "Distribution of 125I-labeled human growth hormone in immature, hypophysectomized rats pretreated with ACTH or unlabeled human growth hormone.", "content": "Distribution of 125I-labeled human growth hormone in immature, hypophysectomized rats pretreated with ACTH or unlabeled human growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362488"}
{"pmid": "4362490", "title": "Patterns of degeneration in the caudal cochlear nucleus of the cat after cochlear ablation.", "content": "Patterns of degeneration in the caudal cochlear nucleus of the cat after cochlear ablation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362490"}
{"pmid": "4362489", "title": "An ultrastructural analysis of spontaneous activation of hamster eggs aged in vivo.", "content": "An ultrastructural analysis of spontaneous activation of hamster eggs aged in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362489"}
{"pmid": "4362492", "title": "Virus resistance transferred from human rheumatoid cells to rabbit synovial cells. II. Cell fusion.", "content": "Virus resistance transferred from human rheumatoid cells to rabbit synovial cells. II. Cell fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362492"}
{"pmid": "4362491", "title": "Effect of glucocorticoids on lysosomes in synovial lining cells in human rheumatoid arthritis.", "content": "Effect of glucocorticoids on lysosomes in synovial lining cells in human rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362491"}
{"pmid": "4362494", "title": "A temperature-jump study of the reaction between azurin and cytochrome c-551 from Pseudomonas aeruginosa.", "content": "A temperature-jump study of the reaction between azurin and cytochrome c-551 from Pseudomonas aeruginosa. Temperature-jump studies on the electron-transfer reaction between azurin and cytochrome c-551 clearly reveal two chemical relaxations. The amplitudes of these relaxation processes have identical spectral distributions, but the relaxation times show different dependences on the reactant concentrations. These findings are discussed in terms of possible models.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362494"}
{"pmid": "4362495", "title": "Involvement of the superoxide anion in sulphoxidation.", "content": "Involvement of the superoxide anion in sulphoxidation. Sulphoxidation of compounds capable of undergoing biological sulphoxidation has been demonstrated in a model system (NADH-phenazine methosulphate-O(2)), known to generate superoxide anions (O(2) (-)). Addition of superoxide dismutase to this system results in complete inhibition, suggesting the involvement of O(2) (-) in sulphoxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362495"}
{"pmid": "4362496", "title": "A rapid method for collecting and assaying gradient fractions for radioactive macromolecules.", "content": "A rapid method for collecting and assaying gradient fractions for radioactive macromolecules. A rapid method is described for collecting gradients after centrifugation, and assaying them for acid-precipitable radioactivity. An entire gradient is collected and processed on a single glass-fibre filter disc. This method allows one easily to assay six gradients for acid-precipitable radioactivity in less than 2h.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362496"}
{"pmid": "4362497", "title": "The evolutionary stability of cytochrome c-551 in Pseudomonas aeruginosa and Pseudomonas fluorescens biotype C.", "content": "The evolutionary stability of cytochrome c-551 in Pseudomonas aeruginosa and Pseudomonas fluorescens biotype C. Cytochrome c-551 was prepared from nine different strains of Pseudomonas aeruginosa and six of Pseudomonas fluorescens biotype C, and their amino acid sequences were compared with the sequences previously determined for the cytochromes of type strains of each species. The standard of sequence examination was such that all single amino acid substitutions, delections or insertions ought to have been detected. Balanced double changes in sites in the same part of the sequence might have escaped detection. The standard of some of the quantitative amino acid analyses was not as high as would be required for the investigation of completely unknown sequences. Eight of the Ps. aeruginosa sequences could not be distinguished from the type sequence, whereas the ninth had a single amino acid substitution. The sequences from Ps. fluorescens biotype C were more varied, differing in from zero to four substitutions from the type sequence, with the most diverse sequences differing in seven positions. The results for Ps. aeruginosa are interpreted as evidence that neutral mutations are not responsible for much molecular evolution. The superficially paradoxical differences in the results for the two species are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362497"}
{"pmid": "4362498", "title": "The amino acid sequences of cytochrome c from four plant sources.", "content": "The amino acid sequences of cytochrome c from four plant sources. Proposed amino acid sequences of cytochrome c from nasturtium (Tropaeolum majus L.), box-elder (Acer negundo L.), elder (Sambucus nigra L.) and parsnip (Pastinaca sativa L.) are presented. Because of the very limited amounts of cytochrome available from some plant sources, peptides derived from the cytochromes c have been sequenced by the semi-quantitative dansyl-Edman technique (Gray & Hartley, 1963) without supporting quantitative amino acid analyses. Because of the qualitative nature of the work, the sequences proposed must be regarded as tentative. Considerations of homology, although useful as a guide, have been kept to a minimum in the construction of sequences. Only the nasturtium sequence relies on considerations of homology for a complete ordering of the peptides. Where material permitted, each residue of a proposed sequence was determined at least once from both a tryptic and a chymotryptic peptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362498"}
{"pmid": "4362499", "title": "Restrained adenyl cyclase in human neutrophils: stimulation of cyclic adenosine 3':5'-monophosphate formation and adenyl cyclase activity by phagocytosis and prostaglandins.", "content": "Restrained adenyl cyclase in human neutrophils: stimulation of cyclic adenosine 3':5'-monophosphate formation and adenyl cyclase activity by phagocytosis and prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362499"}
{"pmid": "4362500", "title": "Single-dose antacid therapy for the prevention of Mendelson's syndrome.", "content": "Single-dose antacid therapy for the prevention of Mendelson's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362500"}
{"pmid": "4362501", "title": "Proceedings: Influence of halothane on mortality from murine hepatitis virus (MHV3).", "content": "Proceedings: Influence of halothane on mortality from murine hepatitis virus (MHV3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362501"}
{"pmid": "4362502", "title": "Influence of norepinephrine-containing neurons derived from the locus coeruleus on lateral geniculate neuronal activities of cats.", "content": "Influence of norepinephrine-containing neurons derived from the locus coeruleus on lateral geniculate neuronal activities of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362502"}
{"pmid": "4362503", "title": "The presence of a factor toxic to pancreatic beta cells in some collagenase preparations.", "content": "The presence of a factor toxic to pancreatic beta cells in some collagenase preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362503"}
{"pmid": "4362493", "title": "Generalized melanosis due to malignant melanoma.", "content": "Generalized melanosis due to malignant melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362493"}
{"pmid": "4362506", "title": "Effects of plasma from hypertensive patients on the responses to angiotensin and norepinephrine in dogs and rats.", "content": "Effects of plasma from hypertensive patients on the responses to angiotensin and norepinephrine in dogs and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362506"}
{"pmid": "4362507", "title": "Comparative study of the effects of metolazone and other diuretics on potassium excretion.", "content": "Comparative study of the effects of metolazone and other diuretics on potassium excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362507"}
{"pmid": "4362508", "title": "Antiviral drugs.", "content": "Antiviral drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362508"}
{"pmid": "4362509", "title": "Prevalence of antibodies against enteroviruses in the populations of Lucknow.", "content": "Prevalence of antibodies against enteroviruses in the populations of Lucknow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362509"}
{"pmid": "4362504", "title": "Wilm's tumor--a clinical review.", "content": "Wilm's tumor--a clinical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362504"}
{"pmid": "4362511", "title": "Adrenocorticotrophic hormone in plasma of mother and newborn.", "content": "Adrenocorticotrophic hormone in plasma of mother and newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362511"}
{"pmid": "4362512", "title": "Nucleotide sequence relationships of avian RNA tumor viruses: measurement of the deletion in a transformation-defective mutant of Rous sarcoma virus.", "content": "Nucleotide sequence relationships of avian RNA tumor viruses: measurement of the deletion in a transformation-defective mutant of Rous sarcoma virus. Stocks of cloned helper-independent Rous sarcoma virus (RSV) spontaneously segregate transformation-defective (td) mutants that appear to have an RNA genome composed of smaller subunits than those of the patent virus. Differential hybridization and competitive hybridization techniques involving reactions between viral RNA and proviral sequences in host cell DNA (under conditions of initial DNA excess) were used to measure the extent of the deletion in a td mutant of Prague strain (Pr) of RSV (Pr RSV-C). Viral 60 to 70S RNA sequences labeled to 1 to 5 x 10(7) counts per min per mug with (125)I were characterized with respect to their properties in hybridization reactions and used to reinforce data obtained with [(3)H]RNA of lower specific activity. By these techniques, about 13% +/- 3% of the sequences Pr RSV-C that formed hybrids with DNA from virus-induced sarcomas appeared to be deleted from the genome of td Pr RSV-C. Studies comparing hybridization of RNA from Pr RSV-C and td Pr RSV-C with RSV-related sequences in normal cells, and competition experiments with RNA from the endogenous chicken oncornavirus Rous-associated virus type 0 (RAV-0) provided evidence that the majority, if not all, of the RNA sequences of Pr RSV-C deleted from its transformation-defective mutant are not represented in normal chicken DNA. Competition studies with a leukosis virus, RAV-7, indicated this virus also lacks a genome segment of about the same size as the deletion in the td mutant. Finally, the genome of all three \"exogenous\" viruses was found to lack a small segment (about 12%) of sequences present in the endogenous provirus of RAV-O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362512"}
{"pmid": "4362510", "title": "Effect of silica on lipid peroxidation in the red cells.", "content": "Effect of silica on lipid peroxidation in the red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362510"}
{"pmid": "4362514", "title": "Effect of D-penicillamine on poliovirus replication in HeLa cells.", "content": "Effect of D-penicillamine on poliovirus replication in HeLa cells. A series of mercaptan compounds were studied with respect to their ability to inhibit the growth of poliovirus in cultured cells. Of the compounds tested only d-penicillamine possessed antiviral activity. There was no direct effect on the virus itself, nor were the processes of adsorption, penetration and uncoating, or virus-induced \"shut-off\" of host cell protein synthesis inhibited. At concentrations where there was no effect on host cell RNA or protein synthesis, d-penicillamine caused a marked inhibition of virus-specific RNA and protein synthesis. Although much reduced, the relative concentrations of single-stranded and double-stranded viral RNA synthesized in the presence of d-penicillamine was unchanged. Similarly, all apparent precursor and cleavage product proteins could be synthesized in the presence of the drug. The inhibitory effect was reversible, after a lag of 1.5 to 2 h after removal of the drug, and normal yields of virus could be obtained. The structural and functional properties of d-penicillamine are discussed in relation to requirements for anti-polioviral activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362514"}
{"pmid": "4362513", "title": "Fate of mRNA of L-cells infected with mengovirus.", "content": "Fate of mRNA of L-cells infected with mengovirus. Mengovirus infection of L-cells results in an inhibition of host protein synthesis which is detectable in vivo by a decreased rate of incorporation of radioactive amino acids into acid-insoluble material and by a concomitant reduction in polysome content. The inhibition of host protein synthesis occurs early in the infection cycle, at a time when there is little synthesis of viral proteins. In this paper the stability of polyadenylic acid [poly(A)]-containing mRNA of uninfected L-cells and cells infected with mengovirus is compared. Our results suggest that there is no increase in the rate of degradation of cellular mRNA upon virus infection. The continued integrity of host mRNA throughout infection was verified by acrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362513"}
{"pmid": "4362505", "title": "Clinical staging system for carcinoma of the lung.", "content": "Clinical staging system for carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362505"}
{"pmid": "4362515", "title": "Genetics and physiology of bacteriophage T4 3'-phosphatase: evidence for involvement of the enzyme in T4 DNA metabolism.", "content": "Genetics and physiology of bacteriophage T4 3'-phosphatase: evidence for involvement of the enzyme in T4 DNA metabolism. Mutants of bacteriophage T4D which fail to induce the deoxyribonucleotide-specific T4 3'-phosphatase have been isolated. These mutants (T4pseT) grow as well as wild-type T4 in most strains of Escherichia coli, but not in the T4-sensitive \"Hospital Strain,\" CT196, or in a derivative strain, CTr5x. Both the formation of infectious centers and the final yield of phage are reduced by 98% when CTr5x is infected by T4pseT mutants. The growth defects are accompanied by a 50% reduction in the rate of T4 DNA synthesis, a decrease in the single-strand length of the DNA product to about one-half the mature length, and greatly reduced packaging of DNA into phage particles. Introduction of an extra-cistronic suppressor mutation (stp) into T4pseT eliminates both the requirement for the T4 3'-phosphatase in infected CTr5x and the other observed effects of the pseT mutations. The pseT gene lies between genes 63 and 31. The stp gene lies in the nonessential region between rIIB and ac. Our results suggest that 3'-phosphoryl termini can disrupt T4 DNA replication to the extent that T4 3'-phosphatase becomes required for phage production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362515"}
{"pmid": "4362516", "title": "Transcription and replication of vesicular stomatitis virus: effects of temperature-sensitive mutations in complementation group IV.", "content": "Transcription and replication of vesicular stomatitis virus: effects of temperature-sensitive mutations in complementation group IV. Temperature-sensitive (ts) mutants of vesicular stomatitis virus belonging to the RNA(-) complementation group IV were investigated under various conditions to study both their RNA and protein syntheses. In infected cells maintained at 39.2 C, viral RNA species were recovered only in the 13 to 15S region of the gradient in an amount depending on the ts mutant used. In the presence of cycloheximide at 39.2 C, the primary transcription was deficient, especially for 28S mRNA production. When mutant-infected cells were shifted to nonpermissive temperature, a shutoff of 28S mRNA synthesis occurred as a general feature. On the contrary under this condition, the two mutants chosen, ts IV100 and ts IV111, behaved very differently in their 13 to 15S and 38S RNA production. However, treatment with cycloheximide at the time of the transfer to 39.2 C resulted in a similar recovery of 13 to 15S RNA in both mutants, whereas the 28S remained very depressed. The viral proteins synthesized by cells infected with the same two mutants also showed a distinct pattern, especially regarding the N protein; a correlation between 38S RNA and protein N syntheses was tentatively drawn. The whole set of data suggested that the lesion in group IV mutants concerned a viral structural protein required for the process of in vivo transcription and which probably intervened in the replication mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362516"}
{"pmid": "4362517", "title": "Mutant of polyoma virus with impaired adsorption to BHK cells.", "content": "Mutant of polyoma virus with impaired adsorption to BHK cells. A mutant of polyoma virus PY235 has an impaired adsorption to guinea pig red blood cells and BHK-21 hamster cells. Adsorption to 3T3 mouse cells is much less inhibited. These altered adsorption properties are responsible for the apparent inability of PY235 to cause cell transformation or hemagglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362517"}
{"pmid": "4362518", "title": "Comparison of 6-94 virus and Sendai virus RNA by RNA-RNA hybridization.", "content": "Comparison of 6-94 virus and Sendai virus RNA by RNA-RNA hybridization. The genomic RNA of 6/94 virus, an agent isolated from the brains of multiple sclerosis patients, was studied for sequence homology by RNA-RNA hybridization with closely related Sendai virus and another paramyxovirus virus, Newcastle disease virus. It was found that the genomic RNA of 6/94 virus hybridizes equally as well to the virus-specific 18S RNA found in Sendai-infected cells as that of Sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362518"}
{"pmid": "4362519", "title": "Submaxillary gland tumors.", "content": "Submaxillary gland tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362519"}
{"pmid": "4362520", "title": "Adenovirus type 4 in Melbourne, 1969-1971.", "content": "Adenovirus type 4 in Melbourne, 1969-1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362520"}
{"pmid": "4362521", "title": "Clinical progress in Crohn's disease.", "content": "Clinical progress in Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362521"}
{"pmid": "4362522", "title": "Protective effects of BCG and other bacteria against neoplasia in mice and hamsters.", "content": "Protective effects of BCG and other bacteria against neoplasia in mice and hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362522"}
{"pmid": "4362523", "title": "Immunotherapeutic studies in mice with the methanol-extraction residue (mer) fraction of BCG: solid tumors.", "content": "Immunotherapeutic studies in mice with the methanol-extraction residue (mer) fraction of BCG: solid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362523"}
{"pmid": "4362524", "title": "Histologic and ultrastructural studies of tumor regression in inbred guinea pigs after intralesional injection of Mycobacterium bovis (BCG).", "content": "Histologic and ultrastructural studies of tumor regression in inbred guinea pigs after intralesional injection of Mycobacterium bovis (BCG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362524"}
{"pmid": "4362525", "title": "The enzymatic ontogeny of neurons and glial cells isolated from postnatal rat cerebral gray matter.", "content": "The enzymatic ontogeny of neurons and glial cells isolated from postnatal rat cerebral gray matter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362525"}
{"pmid": "4362526", "title": "Effect of adrenalectomy on a diurnal (circadian) rhythm in hypothalamic multiple unit activitiy in the female rat.", "content": "Effect of adrenalectomy on a diurnal (circadian) rhythm in hypothalamic multiple unit activitiy in the female rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362526"}
{"pmid": "4362527", "title": "3H-estradiol distribution in normal and androgenized female rats using an improved hypothalamic dissection procedure.", "content": "3H-estradiol distribution in normal and androgenized female rats using an improved hypothalamic dissection procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362527"}
{"pmid": "4362528", "title": "Photoreduction of horse heart cytochrome c.", "content": "Photoreduction of horse heart cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362528"}
{"pmid": "4362529", "title": "Carotenoid chromophore length and protection against photosensitization.", "content": "Carotenoid chromophore length and protection against photosensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362529"}
{"pmid": "4362530", "title": "Neonatal encephalitis following maternal genital herpesvirus infection.", "content": "Neonatal encephalitis following maternal genital herpesvirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362530"}
{"pmid": "4362531", "title": "Some 'pseudo' and some true endocrine syndromes in cancer.", "content": "Some 'pseudo' and some true endocrine syndromes in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362531"}
{"pmid": "4362532", "title": "Cryosurgery in benign conditions of the nose and throat.", "content": "Cryosurgery in benign conditions of the nose and throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362532"}
{"pmid": "4362534", "title": "Interaction of REM deprivation and stage 4 deprivation with total sleep loss: experiment 2.", "content": "Interaction of REM deprivation and stage 4 deprivation with total sleep loss: experiment 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362534"}
{"pmid": "4362533", "title": "The recuperative effects of REM sleep and stage 4 sleep on human performance after complete sleep loss: experiment I.", "content": "The recuperative effects of REM sleep and stage 4 sleep on human performance after complete sleep loss: experiment I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362533"}
{"pmid": "4362537", "title": "A review of 250 cases of Bell's palsy.", "content": "A review of 250 cases of Bell's palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362537"}
{"pmid": "4362543", "title": "Limited proteolysis of alfalfa mosaic virus: influence on the structural and biological function of the coat protein.", "content": "Limited proteolysis of alfalfa mosaic virus: influence on the structural and biological function of the coat protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362543"}
{"pmid": "4362544", "title": "Serological interrelationships in the turnip yellow mosaic virus group.", "content": "Serological interrelationships in the turnip yellow mosaic virus group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362544"}
{"pmid": "4362545", "title": "Identification of a tRNA nucleotidyltransferase and its substrates in virions of avian RNA tumor viruses.", "content": "Identification of a tRNA nucleotidyltransferase and its substrates in virions of avian RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362545"}
{"pmid": "4362546", "title": "Temperature-sensitive defect of type 2 poliovirus.", "content": "Temperature-sensitive defect of type 2 poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362546"}
{"pmid": "4362547", "title": "Recombination between temperature-sensitive mutants of herpes simplex virus type 1.", "content": "Recombination between temperature-sensitive mutants of herpes simplex virus type 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362547"}
{"pmid": "4362548", "title": "RNA polymerase activity and poly(A) synthesizing activity in defective T particles of vesicular stomatitis virus.", "content": "RNA polymerase activity and poly(A) synthesizing activity in defective T particles of vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362548"}
{"pmid": "4362549", "title": "Quantitative electron microscopic analysis of the penetration of VSV into L cells.", "content": "Quantitative electron microscopic analysis of the penetration of VSV into L cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362549"}
{"pmid": "4362550", "title": "Infection of human cells with polyoma virus.", "content": "Infection of human cells with polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362550"}
{"pmid": "4362551", "title": "Temperature-sensitive mutants of murine leukemia virus. 3. Mutants defective in helper functions for sarcoma virus fixation.", "content": "Temperature-sensitive mutants of murine leukemia virus. 3. Mutants defective in helper functions for sarcoma virus fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362551"}
{"pmid": "4362552", "title": "Enhanced activation of the repressed Epstein-Barr viral genome by inhibitors of DNA synthesis.", "content": "Enhanced activation of the repressed Epstein-Barr viral genome by inhibitors of DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362552"}
{"pmid": "4362553", "title": "Synthesis of polyoma virus structural polypeptides in mouse kidney cells.", "content": "Synthesis of polyoma virus structural polypeptides in mouse kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362553"}
{"pmid": "4362554", "title": "Changes in membrane polypeptides that occur when chick embryo fibroblasts and NRK cells are transformed with avian sarcoma viruses.", "content": "Changes in membrane polypeptides that occur when chick embryo fibroblasts and NRK cells are transformed with avian sarcoma viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362554"}
{"pmid": "4362555", "title": "Water-soluble contrast media and adhesive arachnoiditis. II. Reinvestigation of operated cases.", "content": "Water-soluble contrast media and adhesive arachnoiditis. II. Reinvestigation of operated cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362555"}
{"pmid": "4362556", "title": "Value of exercise at one-half earth gravity in preventing the deconditioning effects of simulated weightlessness.", "content": "Value of exercise at one-half earth gravity in preventing the deconditioning effects of simulated weightlessness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362556"}
{"pmid": "4362557", "title": "Ultrastructure and physiological effects of nontobacco cigarettes on Tetrahymena.", "content": "Ultrastructure and physiological effects of nontobacco cigarettes on Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362557"}
{"pmid": "4362558", "title": "Letter: Estrogen therapy for periodic fever.", "content": "Letter: Estrogen therapy for periodic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362558"}
{"pmid": "4362560", "title": "Simulation of cerebral death by succinylcholine sensitivity.", "content": "Simulation of cerebral death by succinylcholine sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362560"}
{"pmid": "4362562", "title": "A short, simple synthetic route to 3-dehydrosphinganine and related compounds.", "content": "A short, simple synthetic route to 3-dehydrosphinganine and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362562"}
{"pmid": "4362559", "title": "Cellular inflammatory response. Findings in patients with neurological diseases.", "content": "Cellular inflammatory response. Findings in patients with neurological diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362559"}
{"pmid": "4362563", "title": "Silicification of developing internodes in the perennial scouring rush (Equisetum hyemale var. affine).", "content": "Silicification of developing internodes in the perennial scouring rush (Equisetum hyemale var. affine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362563"}
{"pmid": "4362564", "title": "Morphological and physiological evidence for the development of functional neuromuscular junctions in vitro.", "content": "Morphological and physiological evidence for the development of functional neuromuscular junctions in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362564"}
{"pmid": "4362565", "title": "Plasma renin concentration: comparison of angiotensinase inhibitors and correlation with plasma renin activity and aldosterone.", "content": "Plasma renin concentration: comparison of angiotensinase inhibitors and correlation with plasma renin activity and aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362565"}
{"pmid": "4362566", "title": "Amylase isoenzymes during viral infections of the pancreas and salivary glands.", "content": "Amylase isoenzymes during viral infections of the pancreas and salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362566"}
{"pmid": "4362570", "title": "Cholestyramine for elevated serum cholesterol.", "content": "Cholestyramine for elevated serum cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362570"}
{"pmid": "4362572", "title": "Hepatic metabolism of estrogens in health and disease.", "content": "Hepatic metabolism of estrogens in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362572"}
{"pmid": "4362573", "title": "Tendon transfers for irreparable peripheral nerve injuries of the upper extremity.", "content": "Tendon transfers for irreparable peripheral nerve injuries of the upper extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362573"}
{"pmid": "4362574", "title": "Tendon transfers in combined nerve lesions.", "content": "Tendon transfers in combined nerve lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362574"}
{"pmid": "4362575", "title": "Skeletal age estimated in a few selected ossification centres of the hand wrist. A simple method for clinical use.", "content": "Skeletal age estimated in a few selected ossification centres of the hand wrist. A simple method for clinical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362575"}
{"pmid": "4362585", "title": "Intestinal parasites in Amerindians of the interior of Surinam.", "content": "Intestinal parasites in Amerindians of the interior of Surinam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362585"}
{"pmid": "4362586", "title": "A comparative study of the rates of metabolism, L.D. 50's and antiacetylcholinesterase activities of three diethylphosphoryl esters of quinolinols.", "content": "A comparative study of the rates of metabolism, L.D. 50's and antiacetylcholinesterase activities of three diethylphosphoryl esters of quinolinols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362586"}
{"pmid": "4362589", "title": "Proceedings: Evidence for a dopaminergic mechanism for modulation of adrenergic transmission in the rabbit ear artery.", "content": "Proceedings: Evidence for a dopaminergic mechanism for modulation of adrenergic transmission in the rabbit ear artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362589"}
{"pmid": "4362588", "title": "Adrenoceptors and adenyl cyclase in gills.", "content": "Adrenoceptors and adenyl cyclase in gills. The content of cyclic 3',5'-adenosine monophosphate (cAMP) in the gills of the mullet (Mugil capito) has been measured. The basal level was found to be 2.9+/-0.3 pmol/mg wet weight. When fish were first anaesthetized with MS222 (tricaine) and the gills perfused to remove blood, the concentration of cAMP was raised to 14.3+/-1.9 pmol/mg wet weight.Adrenaline caused a significant increase in cAMP content, an effect that was blocked by propranalol, a beta-adrenoceptor antagonist. In the presence of the alpha-adrenoceptor block- ing agent phentolamine, adrenaline still caused an increase in nucleotide content.The results are discussed in relation to adrenaline and the adenyl cyclase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362588"}
{"pmid": "4362590", "title": "Proceedings: Drinking in the cat induced by centrally administered angiotensin.", "content": "Proceedings: Drinking in the cat induced by centrally administered angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362590"}
{"pmid": "4362592", "title": "Sleep induced by small doses of tubocurarine injected into cerebral ventricles of dog.", "content": "Sleep induced by small doses of tubocurarine injected into cerebral ventricles of dog. In unanaesthetized dogs, sleep with the typical sleep pattern in the E.E.G. was produced with (+)-tubocurarine when injected in a small dose (500 ng) into, or perfused in low concentration (100 ng/ml) through the cerebral ventricles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362592"}
{"pmid": "4362591", "title": "Proceedings: Potentiation of dubutyryl cyclic 3'5'-AMP-induced gastric acid secretion in rats by non-steroidal anti-inflammatory drugs.", "content": "Proceedings: Potentiation of dubutyryl cyclic 3'5'-AMP-induced gastric acid secretion in rats by non-steroidal anti-inflammatory drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362591"}
{"pmid": "4362594", "title": "Developmental change of choline acetyltransferase and acetylcholinesterase in the ciliary and the superior cervical ganglion of the chick.", "content": "Developmental change of choline acetyltransferase and acetylcholinesterase in the ciliary and the superior cervical ganglion of the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362594"}
{"pmid": "4362593", "title": "The influence of histamine and other vasoactive substances on contractile responses of cat skeletal muscle to acetylcholine.", "content": "The influence of histamine and other vasoactive substances on contractile responses of cat skeletal muscle to acetylcholine. 1. The effect of vasoactive substances, chiefly histamine, on contractions of cat skeletal muscle evoked by acetylcholine has been studied. For this purpose all of these agents were administered intra-arterially to anterior tibialis, chiefly, and also to soleus and external rectus muscles in vivo.2. Under these conditions, histamine itself never altered the resting tension of the muscle, but always enhanced the increase in tension produced by acetylcholine injected shortly afterward.3. On the anterior tibialis muscle, it was determined that the threshold potentiating dose of histamine was 0.001 mug/kg, and that maximal enhancement occurred when 0.1 mug/kg was injected 15 s before fixed, submaximal doses of acetylcholine. Injected 15 s before graded doses of acetylcholine, histamine 0.1 mug/kg shifted the acetylcholine dose-response curves approximately 1.5 log units to the left.4. Under similar experimental conditions the vasodilator, bradykinin, 0.001-1 mug/kg, and procedures which produce a local increase in nutritive capillary blood flow also enhanced acetylcholine-evoked contractile responses of the anterior tibialis, whereas the vasoconstrictor, angiotensin, 0.001-1 mug/kg, inhibited them.5. The potentiating effect of histamine was antagonized by mepyramine, but was undiminished by denervation of the muscle either acutely or for 4 days.6. Histamine failed to enhance responses of the muscle to electrical stimulation of either the muscle, directly, or its motor nerve.7. Histamine also had no effect upon acetylcholine-evoked responses of the isolated external rectus muscle in vitro.8. It is suggested that the potentiating effect of histamine in vivo is due to its vasodilator action within the muscles which, by relaxing arterioles and precapillary sphincters, could allow more of the blood-borne acetylcholine to reach more of its receptors on the muscle fibres in a given time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362593"}
{"pmid": "4362595", "title": "Effects of taurine on cortical acute epileptic foci.", "content": "Effects of taurine on cortical acute epileptic foci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362595"}
{"pmid": "4362596", "title": "Electron histochemical evidence for the role of thiamine pyrophosphatase in synaptic transmission.", "content": "Electron histochemical evidence for the role of thiamine pyrophosphatase in synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362596"}
{"pmid": "4362597", "title": "Localization of opiate receptor binding in synaptic membranes of rat brain.", "content": "Localization of opiate receptor binding in synaptic membranes of rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362597"}
{"pmid": "4362601", "title": "Maintenance of primary African green monkey kidney (pAGMK) and Vero cells at room temperature (25 degrees). A system for virus isolation in community practice.", "content": "Maintenance of primary African green monkey kidney (pAGMK) and Vero cells at room temperature (25 degrees). A system for virus isolation in community practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362601"}
{"pmid": "4362603", "title": "The human spermatozoon. An electron microscopical study including comparative details of Macaca arctoides spermatozoa.", "content": "The human spermatozoon. An electron microscopical study including comparative details of Macaca arctoides spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362603"}
{"pmid": "4362604", "title": "A protein kinase assayable with intact cells of the cellular slime mold Dictyostelium discoideum.", "content": "A protein kinase assayable with intact cells of the cellular slime mold Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362604"}
{"pmid": "4362605", "title": "Cytoplasmic control of nuclear activity in preimplantation mouse embryos.", "content": "Cytoplasmic control of nuclear activity in preimplantation mouse embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362605"}
{"pmid": "4362606", "title": "Inverted caloric nystagmus.", "content": "Inverted caloric nystagmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362606"}
{"pmid": "4362607", "title": "The importance of dose and proliferation of SV40-transformed cells with different oncogenic potentials to the level of tumor immunity.", "content": "The importance of dose and proliferation of SV40-transformed cells with different oncogenic potentials to the level of tumor immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362607"}
{"pmid": "4362608", "title": "Further studies on SV40 permissive cell protein factor(s) allowing rescue of infectious virus and viral DNA from non-shedder SV40-transformed cells.", "content": "Further studies on SV40 permissive cell protein factor(s) allowing rescue of infectious virus and viral DNA from non-shedder SV40-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362608"}
{"pmid": "4362609", "title": "EB virus-associated antibodies in Caucasian patients with carcinoma of the nasopharynx and in long-term survivors after treatment.", "content": "EB virus-associated antibodies in Caucasian patients with carcinoma of the nasopharynx and in long-term survivors after treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362609"}
{"pmid": "4362610", "title": "Comparison of EBV neutralization tests based on abortive infection or transformation of lymphoid cells and their relation to membrane reactive antibodies (anti-MA).", "content": "Comparison of EBV neutralization tests based on abortive infection or transformation of lymphoid cells and their relation to membrane reactive antibodies (anti-MA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362610"}
{"pmid": "4362612", "title": "Effects of adenosine 3'5'-cyclic monophosphoric acid on the morphology, growth and cell cycle of Earle's L cells.", "content": "Effects of adenosine 3'5'-cyclic monophosphoric acid on the morphology, growth and cell cycle of Earle's L cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362612"}
{"pmid": "4362611", "title": "Epstein-Barr virus: transformation of non-human primate lymphocytes in vitro.", "content": "Epstein-Barr virus: transformation of non-human primate lymphocytes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362611"}
{"pmid": "4362613", "title": "Characteristics of murine C-type viruses. 3. Antigenic conversion and focus induction.", "content": "Characteristics of murine C-type viruses. 3. Antigenic conversion and focus induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362613"}
{"pmid": "4362614", "title": "Characteristics of murine C-type viruses. IV. The virus produced by Ehrlich tumor cells and it hybrids with mouse L cells.", "content": "Characteristics of murine C-type viruses. IV. The virus produced by Ehrlich tumor cells and it hybrids with mouse L cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362614"}
{"pmid": "4362615", "title": "The transition from sleep to wakefulness: implications of a study of the organization of laboratory dream reports for the psychoanalytic situation.", "content": "The transition from sleep to wakefulness: implications of a study of the organization of laboratory dream reports for the psychoanalytic situation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362615"}
{"pmid": "4362616", "title": "A medium for overcoming the in vitro inhibition of Clostridium perfringens by Streptococcus faecalis var. zymogenes, and a note on the in vivo interaction of the two organisms.", "content": "A medium for overcoming the in vitro inhibition of Clostridium perfringens by Streptococcus faecalis var. zymogenes, and a note on the in vivo interaction of the two organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362616"}
{"pmid": "4362617", "title": "A method for preparing a pre-reduced, chemically defined, filter sterilized medium for growing Clostridium perfringens.", "content": "A method for preparing a pre-reduced, chemically defined, filter sterilized medium for growing Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362617"}
{"pmid": "4362619", "title": "The presence and function of cytochromes in Selenomonas ruminantium, Anaerovibrio lipolytica and Veillonella alcalescens.", "content": "The presence and function of cytochromes in Selenomonas ruminantium, Anaerovibrio lipolytica and Veillonella alcalescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362619"}
{"pmid": "4362618", "title": "R factors from Providence.", "content": "R factors from Providence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362618"}
{"pmid": "4362622", "title": "The interaction between divalent cations and botulinum toxin type A in the paralysis of the rat phrenic nerve-hemidiaphragm preparation.", "content": "The interaction between divalent cations and botulinum toxin type A in the paralysis of the rat phrenic nerve-hemidiaphragm preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362622"}
{"pmid": "4362620", "title": "Subacute sclerosing panencephalitis. Elevated Epstein-Barr virus antibody titers and failure of amantadine therapy.", "content": "Subacute sclerosing panencephalitis. Elevated Epstein-Barr virus antibody titers and failure of amantadine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362620"}
{"pmid": "4362621", "title": "Induction, detection and characterization of cell differentiation mutants in Drosophila.", "content": "Induction, detection and characterization of cell differentiation mutants in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362621"}
{"pmid": "4362625", "title": "Replication of the resident repressed Epstein-Barr virus genome during the early S phase (S-1 period) of nonproducer Raji cells.", "content": "Replication of the resident repressed Epstein-Barr virus genome during the early S phase (S-1 period) of nonproducer Raji cells. Replication of the resident repressed Epstein-Barr virus genome in synchronized nonproducer Raji cells was shown to occur during the early S phase (S-1 period) by hybridization of cell DNA with virus-specific complementary RNA (cRNA). The S-1 period was previously identified as the critical period for virus activation induced by thymidine analogues. The findings reported here and elsewhere are consistent with the proposal that: (i) virus activation is initiated at or near the site of association of the resident viral genome with cell DNA, (ii) replication of the resident virus genome in nonactivated cells is under cell control mechanisms, and (iii) the resident virus genome is physically associated with early replicating cell DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362625"}
{"pmid": "4362626", "title": "In vitro activation of the transcription of araBAD operon by araC activator.", "content": "In vitro activation of the transcription of araBAD operon by araC activator. The transcription of araBAD operon requires araC activator and cyclic AMP. D-Fucose inhibits ara mRNA synthesis. Our results indicate that the positive control by araC activator is exerted at the level of transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362626"}
{"pmid": "4362628", "title": "Fractionation of DNA on hydroxyapatite with a base-specific complexing agent.", "content": "Fractionation of DNA on hydroxyapatite with a base-specific complexing agent. We describe a chromatographic technique for separating mixtures of DNA of varying G + C content. The method employs a specially prepared high-capacity hydroxyapatite and a G.C-specific DNA ligand (2-methyl-3-amino-7-dimethylamino-5-phenyl-phenazinium cation, abbreviated PNR). DNA molecules rich in G.C pairs bind larger amounts of this dye and are eluted earlier from the hydroxyapatite column than are molecules rich in A.T pairs. The dye can easily be removed from DNA by dialysis or solvent extraction after the chromatographic separation. The resolution of the method approaches that of CsCl density gradient separation, and the capacity of the column is much larger than that of a typical density gradient experiment. Elution of the DNA is not dependent on molecular weight, so samples of different molecular weight can be separated on the basis of G + C content. The technique should be especially useful for separating G.C-rich minor components from DNA obtained form eukaryotic cells, as demonstrated by a fraction of DNA from calf thymus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362628"}
{"pmid": "4362627", "title": "Intracellular cyclic AMP concentration responds specifically to growth regulation by serum.", "content": "Intracellular cyclic AMP concentration responds specifically to growth regulation by serum. Intracellular concentrations of cyclic AMP increase when cells are deprived of serum. Studies with the mouse fibroblast line 3T3, an SV40-transformed subline of 3T3, and six different revertant lines derived from this clone show that a marked increase in cyclic AMP occurs only when the serum concentration is reduced below the minimum necessary for growth of a given line. Conversely, density-dependent inhibition of growth is not accompanied by an increase in cyclic AMP concentration in any line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362627"}
{"pmid": "4362629", "title": "Reversion of a Chinese hamster cell auxotrophic mutant.", "content": "Reversion of a Chinese hamster cell auxotrophic mutant. A mutant cell strain derived from a Chinese hamster line by mutagenesis with ethylmethane sulfonate requires glycine for growth. In the wild type, glycine synthesis is catalyzed by serine hydroxymethyltransferase (EC 2.1.2.1). Cell fractionation by differential centrifugation and isopycnic sucrose gradient analysis reveals that the enzyme activity is found in both the mitochondrial and cytosol fractions. The specific activity in the mitochondrial fraction is about 20 times higher than in the cytosol, and is much more stable to thermal inactivation. The glycine-requiring mutant has lost all of the mitochondrial enzyme activity, while retaining the cytosol activity. The mutant is very stable but can be induced to revert by several chemical mutagens. One glycine-independent revertant induced by ethyl methane sulfonate was studied in detail. Serine hydroxymethyltransferase activity is again present in the mitochondrial fraction, at about [unk] of the wild-type level. However, the revertant mitochondrial enzyme exhibits an altered thermal sensitivity, with a half-life at 45 degrees of 55 min as compared to 180 min in the wild type. The half-life for the cytosol enzyme in all three strains is 7 min. Mixing experiments demonstrate that the heat lability of the revertant enzyme is not due to a dissociable factor in the extract. The data are consistent with the idea that the original mutation occurred in the structural gene for one isozyme of the enzyme and that the revertant has undergone a second mutation in this gene, partially restoring enzyme activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362629"}
{"pmid": "4362630", "title": "Parathyroid hormone receptors of renal cortex: specific binding of biologically active, 125I-labeled hormone and relationship to adenylate cyclase activation.", "content": "Parathyroid hormone receptors of renal cortex: specific binding of biologically active, 125I-labeled hormone and relationship to adenylate cyclase activation. Biologically active (125)I-labeled bovine parathyroid hormone (prepared by electrolytic iodination) and its synthetic NH(2)-terminal (1-34) biologically active fragment bound rapidly and specifically to a purified plasma membrane preparation from bovine renal cortex. Binding of labeled intact hormone or labeled NH(2)-terminal (1-34) peptide was inhibited competitively by unlabeled (1-34) peptide in the same range of concentrations that activated renal cortical 3':5'-adenylate cyclase (EC 4.6.1.1) in these membranes. The concentrations of synthetic (1-34) peptide for half-maximal inhibition of binding of labeled hormone as well as half-maximal activation of the enzyme were about 0.6 muM (2.5 mug/ml). Therefore it is likely that the binding activity studied represents a physiologically important renal receptor for parathyroid hormone. Biologically inactive (oxidized) forms of parathyroid hormone and (1-34) NH(2)-terminal peptide as well as calcitonin, glucagon, insulin, and epinephrine failed to competitively inhibit the binding of labeled (1-34) parathyroid hormone or activate adenylate cyclase in the renal cortical membrane preparation. Observations with the NH(2)-terminal (1-34) biologically active fragment of parathyroid hormone suggest that the COOH-terminal region of the molecule is not required for receptor binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362630"}
{"pmid": "4362631", "title": "Introduction of specific cleavages into RNAs of RNA bacteriophages for determination of base sequences.", "content": "Introduction of specific cleavages into RNAs of RNA bacteriophages for determination of base sequences. Large fragments of R17, MS2, and Qbeta RNAs were obtained reproducibly by limited digestion by ribonuclease T1. After digestion of R17 and MS2 RNAs, two pairs of large fragments were obtained that probably resulted from specific cleavages of the whole molecules. The cleavages of MS2 RNA were produced at points 36 and 47% from the 5' end.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362631"}
{"pmid": "4362632", "title": "The roles of the lambda c3 gene and the Escherichia coli catabolite gene activation system in the establishment of lysogeny by bacteriophage lambda.", "content": "The roles of the lambda c3 gene and the Escherichia coli catabolite gene activation system in the establishment of lysogeny by bacteriophage lambda. Maximum lysogenization of E. coli by bacteriophage lambda requires both the lambdacIII gene function and the host catabolite gene activation system mediated by adenosine 3':5'-cyclic monophosphate. Whereas considerable lysogenization occurs in the presence of either system alone, lysogenization is absolutely prevented in the absence of both systems. Neither system is, however, required for efficient lysogenization when the host bears an hfl(-) mutation. It is argued that the normal function of these two systems is to negate the antagonistic effect of the Hfl(+) protein upon lysogenization. It is further argued that both the lambdacIII gene function and the Hfl(+) protein do not directly affect the host catabolite gene activation system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362632"}
{"pmid": "4362633", "title": "Association of DNA-dependent and  -independent ribonucleoside triphosphatase activities with dnaB gene product of Escherichia coli.", "content": "Association of DNA-dependent and  -independent ribonucleoside triphosphatase activities with dnaB gene product of Escherichia coli. Preparations of E. coli dnaB gene product contain ribonucleoside triphosphatase activity that is stimulated 10-fold by DNA. The products of the triphosphatase activity are nucleoside diphosphates and P(i). The dnaB complementing activity in the varphiX174 DNA-dependent system and these triphosphatase activities copurify over the last 20-fold of an extensive (about 40,000-fold) purification procedure. Acrylamide gel electrophoresis of the purified material shows a single band of protein coincident with eluted dnaB complementing and DNA-dependent and -independent nucleoside triphosphatase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362633"}
{"pmid": "4362634", "title": "Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.", "content": "Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. Monolayers of cultured fibroblasts from normal human subjects bind (125)I-labeled low-density lipoproteins with high affinity and specificity. High affinity binding of similar magnitude was not observed in cells from five unrelated subjects with the homozygous form of familial hypercholesterolemia. In normal cells incubated at 37 degrees , the binding sites were saturated at a low-density lipoprotein concentration of 20 mug/ml. A maximum of approximately 250,000 molecules could be bound to each cell. Whole serum and very-low-density lipoproteins displaced (125)I-labeled low-density lipoproteins from the binding sites, but high-density lipoproteins, the lipoprotein-deficient fraction of serum, and abetalipoproteinemic serum did not. This binding appears to be a required step in the process by which low-density lipoproteins normally suppress the synthesis of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, the rate-controlling enzyme in cholesterol biosynthesis. The demonstration of a defect in binding of low-density lipoproteins to cells from subjects with the homozygous form of familial hypercholesterolemia appears to explain the previously reported failure of lipoproteins to suppress the synthesis of this enzyme and hence may account for the overproduction of cholesterol that occurs in these cultured cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362634"}
{"pmid": "4362636", "title": "Prediction of secondary structure of proteins. A comparison of the phi, psi angles previously predicted for cytochrome c with recent x-ray crystallographic findings.", "content": "Prediction of secondary structure of proteins. A comparison of the phi, psi angles previously predicted for cytochrome c with recent x-ray crystallographic findings. Newer data from the x-ray crystallographic studies of tuna heart ferrocytochrome c have increased the number of residues in alpha-helical segments. This provided an objective test of our method of predicting varphi,Psi values for cytochrome c using the sequences of 18 cytochromes c and twenty 20 x 20 tables for the varphi,Psi values of tripeptides in 10 other proteins whose three-dimensional structures were known from x-ray crystallographic studies. Of the 32 residues now considered from x-ray data to be in alpha-helices, 27 had been predicted to be in the alpha-helical domain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362636"}
{"pmid": "4362635", "title": "Alteration of vein cyclic 3':5' nucleotide concentrations during changes in contractility.", "content": "Alteration of vein cyclic 3':5' nucleotide concentrations during changes in contractility. The relative changes in vascular tissue levels of cyclic 3':5'-guanosine monophosphate (cGMP) and cyclic 3':5'-adenosine monophosphate (cAMP) were determined in bovine and canine vein strips that were quickfrozen during changes in contractility elicited by prostaglandins (PG) or isoproterenol. Prostaglandin F(2alpha)-induced venoconstriction was associated with increased vascular tissue levels of cGMP and increased ratios of cGMP to cAMP concentrations, but no consistent qualitative change in cAMP levels. In contrast, vein cAMP concentrations were increased during administration of the vasodilators PGE(2) and isoproterenol. The results suggest possible opposing roles for the two cyclic nucleotides in vasomotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362635"}
{"pmid": "4362637", "title": "Electron spin resonance studies of erythrocytes from patients with myotonic muscular dystrophy.", "content": "Electron spin resonance studies of erythrocytes from patients with myotonic muscular dystrophy. Electron magnetic resonance experiments have demonstrated that spin-labeled myotonic erythrocyte membranes have spectra that are recognizably different from those of normal erythrocytes. The spin label incorporated in the erythrocyte membranes of patients having myotonic muscular dystrophy is apparently located in a less polar and somewhat more fluid region than the label in a normal membrane. Although the mechanisms of molecular interaction and their relationship to enzymatic differences is unclear, the results lend confirmation to the suggestion that myotonic muscular dystrophy may be a disease resulting from a basic membrane abnormality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362637"}
{"pmid": "4362638", "title": "The electrostatic basis of Mg++ inhibition of transmitter release.", "content": "The electrostatic basis of Mg++ inhibition of transmitter release. The inhibition by Mg(++) of stimulus-evoked transmitter release is attributed to a decrease in surface potential, Psi(0), on the outer surface of the presynaptic terminal and hence a lower surface calcium concentration, [Ca(++)](0). Data on the frog neuromuscular junction are quantitatively fit by assuming that there is a negative charge density, sigma, on the outer surface of the presynaptic terminal of 6.5 x 10(13) charges per cm(2) and that simple diffuse double layer theory is applicable. No specific binding of Mg(++) or Ca(++) is required. Without any additional assumptions, the inhibitory effect of univalent cations is also quantitatively predicted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362638"}
{"pmid": "4362639", "title": "Expression of differentiated functions in hepatoma cell hybrids: high frequency of induction of mouse albumin production in rat hepatoma-mouse lymphoblast hybrids.", "content": "Expression of differentiated functions in hepatoma cell hybrids: high frequency of induction of mouse albumin production in rat hepatoma-mouse lymphoblast hybrids. We have studied the production of serum albumin by somatic hybrids between well-differentiated 2s and 1s rat hepatoma cells (Faza), which produce serum albumin, and sub-diploid mouse leukemic lymphoblasts (Lc), which do not produce albumin. We determined the rat or mouse origin of the albumin by double immunodiffusion, using immuno-adsorbed noncrossreacting antisera. Each of 12 karyologically identified 2s hybrid clones (Lc2F) produces both rat and mouse albumin. Moreover, unlike 1s hybrids reported previously, eight of nine 1s hybrids (LcF) also produce mouse albumin; six of them produce rat albumin as well. One clone from the 1s cross produces only rat albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362639"}
{"pmid": "4362641", "title": "Human antigen and enzyme markers in man-Chinese hamster somatic cell hybrids: evidence for synteny between the HL-A, PGM3, ME1, and IPO-B loci.", "content": "Human antigen and enzyme markers in man-Chinese hamster somatic cell hybrids: evidence for synteny between the HL-A, PGM3, ME1, and IPO-B loci. In man-Chinese hamster somatic cell hybrids the segregation of the loci for 27 human enzyme markers and the species-specific surface antigens, including the HL-A histocompatibility antigens, was studied. The results show a synteny of the human loci for phosphoglucomutase 3, cytoplasmic malic enzyme, tetrameric indophenol oxidase, and HL-A. Furthermore, evidence is presented that the loci for the human species-specific antigens are distributed over several chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362641"}
{"pmid": "4362640", "title": "The isolation of simian virus 40 variants with specifically altered genomes.", "content": "The isolation of simian virus 40 variants with specifically altered genomes. Serial passage of simian virus 40 (SV40) at high multiplicity of infection leads to the emergence of variants with deleted, substituted, and/or duplicated DNA. Individual variants have been cloned by selective complementation with temperature sensitive SV40 mutants, or nonselectively by coinfection of cells with wild-type helper virus. In each case, the presence of variants was detected by the appearance of discrete short viral genomes in infected cell lysates. Such short genomes, isolated by agarose gel electrophoresis, were shown to be specifically altered by comparing the electrophoretic pattern of their DNA fragments produced by Haemophilus influenzae restriction endonuclease with the pattern of fragments from parental DNA. In addition to defective variants, one infectious variant that had an additional segment of DNA within its genome was isolated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362640"}
{"pmid": "4362645", "title": "Current concepts in diagnosis of insulinoma.", "content": "Current concepts in diagnosis of insulinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362645"}
{"pmid": "4362642", "title": "Identification of a high affinity nuclear acceptor site for estrogen receptor of calf uterus.", "content": "Identification of a high affinity nuclear acceptor site for estrogen receptor of calf uterus. By means of affinity chromatography, specific nuclear acceptor sites for estradiol receptors are identified in a fraction that can be solubilized from purified nuclei with 2 M NaCl. Interaction between these acceptor sites and crude or partially purified estradiol receptor shows a high association constant (over 10(9) M). Receptor-acceptor interaction is dependent on physiological concentrations of 17beta-estradiol; it is disrupted by high ionic strength. The nuclear acceptor sites appear to be protein in nature and exist in 5- to 10-fold excess over the estrogen binding sites present in the cytosol. Single- or double-stranded DNA does not bind estrogen-receptor complexes. Acceptor sites appear to be associated with basic nuclear proteins as judged by hydroxyapatite chromatography. The nuclear acceptor sites probably represent less than 0.1% of the purified basic proteins from the nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362642"}
{"pmid": "4362644", "title": "Genetic differentiation within and between species of the Drosophila willistoni group.", "content": "Genetic differentiation within and between species of the Drosophila willistoni group. We describe allelic variation at 28 loci in six Caribbean populations of four sympatric species of Drosophila. Within any one species the allelic frequencies are very similar from population to population, although there is evidence of local as well as regional genetic differentiation. The genetic distance is greater between populations from different islands than between populations of the same island. When the allelic frequencies are compared between different species, a remarkable pattern appears. In any pair of species nearly half of the loci have essentially identical allelic frequencies, while nearly the other half of the loci have different alleles and in different frequencies. The loci with nearly identical allelic frequencies are different when different pairs of species are compared. The patterns of allelic variation within and between species are inconsistent with the hypothesis that the variation is adaptively neutral. Migration or mutation cannot explain the patterns of genetic variation, either. Balancing natural selection is the main process maintaining protein polymorphisms in natural populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362644"}
{"pmid": "4362643", "title": "Lipid-protein interactions in high density lipoproteins.", "content": "Lipid-protein interactions in high density lipoproteins. Delipidated high density lipoprotein (apo-HDL), isolated apolipoproteins apoA-I and apoA-II, S-carboxymethylated apoA-II, apoC-III, the NH(2)- and COOH-terminal CNBr peptides of apoA-II, and the COOH-terminal CNBr peptide of apoA-I were recombined in vitro with [N-C(3)H(3)-choline]phosphatidylcholine (PC) and [N-(14)CH(3)-choline]sphingomyelin (SPM). The lipid-protein complexes were analyzed by ultracentrifugal flotation, agarose gel chromatography and circular dichroism. ApoHDL, apoA-II, and S-carboxymethylated apoA-II readily recombined with PC or SPM to form particles that were similar in size to native HDL. The COOH- but not the NH(2)-terminal CNBr peptide of apoA-II recombined with lipid. ApoA-I and the COOH-terminal CNBr peptide of apoA-I, however, recombined with PC or SPM to only a limited extent, suggesting that protein-protein interactions between apoA-I and apoA-II are important in the integration of apoA-I into recombined lipoprotein particles. Analysis of the recombined lipid-protein complexes by circular dichroism indicated that there was an increase in helical structure concomitant with lipid-protein binding. The reconstituted particles had many of the physical and chemical properties of the native lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362643"}
{"pmid": "4362650", "title": "Life cycle of the murine mammary tumor virus, and a comparison with similar forms reported in human mammary carcinomas.", "content": "Life cycle of the murine mammary tumor virus, and a comparison with similar forms reported in human mammary carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362650"}
{"pmid": "4362648", "title": "Treatment of common enteric parasites.", "content": "Treatment of common enteric parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362648"}
{"pmid": "4362649", "title": "Prevalence and intensity of intestinal parasitism on Talim Island, Binangonan, Rizal, Philippines.", "content": "Prevalence and intensity of intestinal parasitism on Talim Island, Binangonan, Rizal, Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362649"}
{"pmid": "4362651", "title": "Common antigens in herpesviruses from divergent species of animals.", "content": "Common antigens in herpesviruses from divergent species of animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362651"}
{"pmid": "4362653", "title": "Further evidence for a humoral control of factor VIII plasma levels.", "content": "Further evidence for a humoral control of factor VIII plasma levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362653"}
{"pmid": "4362654", "title": "Effect of corticosteroids upon fibrinogen metabolism in rabbits.", "content": "Effect of corticosteroids upon fibrinogen metabolism in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362654"}
{"pmid": "4362663", "title": "Adenoid cystic carcinoma of the breast.", "content": "Adenoid cystic carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362663"}
{"pmid": "4362662", "title": "Adrenocortical function of patients using oral contraceptives.", "content": "Adrenocortical function of patients using oral contraceptives. To investigate the possible changes in adrenocortical function during the use of different oral contraceptives, 43 women of fertile age were studied.  35 were using orgal contraceptives of the estrogen-gestagen type, the estrogen-gestagen sequential type, or the low-gestagen type.  8 women were controls.  Each member of the test groups had been taking contraceptive pills for at least 2 menstrual cycles.  Adrenocortical function was measured by assaying photofluorimetrically the 11-OHCS content of the plasma during the synthetic adrenocortioctrophic hormone (ACTH) (Homactid) test.  The dose of the hormone used was 10 mcg given im.  Plasma samples were obtained before and 15, 30, 60, and 120 minutes after injection.  Tests were done on Days 15-20 of the menstrual cycles.  The plasma 11-OCHS level in the low-gestagen group was the same as in controls both before and during the test.  The combined type contraceptives had an elevating effect on the 11-OHCS level in the plasma; these levels both before and during the ACTH test ranged from nearly significant to p less than .01 with some of the readings reaching significance  at the p less than .001.  The difference is assumed to be due to an increased transcorting content of the plasma and to the increased biological half-life of cortisol induced by estrogen.  This could also explain why the metabolic change noted in association with estrogen-gestagen oral contraceptives is similar to that seen in corticosteroid-induced diabetes.  Similar readings were found for the patients taking the sequential contraceptives, with values ranging from nearly significant at 0-15 minutes to highly significant (p less than .001) from 30 to 120 minutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362662"}
{"pmid": "4362664", "title": "Evidence that the polyadenylic acid segment of \"35S\" RNA of avian myeloblastosis virus is located at the 3'-OH terminus.", "content": "Evidence that the polyadenylic acid segment of \"35S\" RNA of avian myeloblastosis virus is located at the 3'-OH terminus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362664"}
{"pmid": "4362665", "title": "Systematic identification of aldehydes and aldehyde-derived crosslinks in elastin by methods including a modified Strecker reaction.", "content": "Systematic identification of aldehydes and aldehyde-derived crosslinks in elastin by methods including a modified Strecker reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362665"}
{"pmid": "4362667", "title": "The relationship of polyoma virus-induced tumor (T) antigen to activation of DNA synthesis in rat myotubes.", "content": "The relationship of polyoma virus-induced tumor (T) antigen to activation of DNA synthesis in rat myotubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362667"}
{"pmid": "4362668", "title": "Expression of liver phenotypes in cultured mouse hepatoma cells: synthesis and secretion of serum albumin.", "content": "Expression of liver phenotypes in cultured mouse hepatoma cells: synthesis and secretion of serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362668"}
{"pmid": "4362669", "title": "Management of travellers' diarrhoea.", "content": "Management of travellers' diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362669"}
{"pmid": "4362673", "title": "Abnormal degradation of macroaggregated albumin particles in patients with asthma.", "content": "Abnormal degradation of macroaggregated albumin particles in patients with asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362673"}
{"pmid": "4362675", "title": "Chemodectoma of the urinary bladder in a dog.", "content": "Chemodectoma of the urinary bladder in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362675"}
{"pmid": "4362674", "title": "Epidermal adenyl cyclase of human and mouse. A study of the atopic state.", "content": "Epidermal adenyl cyclase of human and mouse. A study of the atopic state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362674"}
{"pmid": "4362677", "title": "The biosynthesis of folic acid. XII. Purification and properties of dihydroneopterin triphosphate pyrophosphohydrolase.", "content": "The biosynthesis of folic acid. XII. Purification and properties of dihydroneopterin triphosphate pyrophosphohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362677"}
{"pmid": "4362676", "title": "Cobamides and ribonucleotide reduction. XII. The electron paramagnetic resonance spectrum of \"active coenzyme B12\".", "content": "Cobamides and ribonucleotide reduction. XII. The electron paramagnetic resonance spectrum of \"active coenzyme B12\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362676"}
{"pmid": "4362678", "title": "The molecular properties of ApoA-I from human high density lipoprotein.", "content": "The molecular properties of ApoA-I from human high density lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362678"}
{"pmid": "4362679", "title": "Neurospora crassa protein kinase. Purification, properties, and kinetic mechanism.", "content": "Neurospora crassa protein kinase. Purification, properties, and kinetic mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362679"}
{"pmid": "4362680", "title": "Glucocorticoid receptors in fetal and adult rabbit tissues.", "content": "Glucocorticoid receptors in fetal and adult rabbit tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362680"}
{"pmid": "4362681", "title": "The b-cytochromes of plant mitochondria. A spectrophotometric and potentiometric study.", "content": "The b-cytochromes of plant mitochondria. A spectrophotometric and potentiometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362681"}
{"pmid": "4362682", "title": "The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents.", "content": "The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362682"}
{"pmid": "4362684", "title": "Immunological specificities of lysine-rich histones from tumors.", "content": "Immunological specificities of lysine-rich histones from tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362684"}
{"pmid": "4362683", "title": "Structural analysis of ribosomal 28 S ribonucleic acid of Novikoff hepatoma cells.", "content": "Structural analysis of ribosomal 28 S ribonucleic acid of Novikoff hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362683"}
{"pmid": "4362685", "title": "Role of photophosphorylation coupling factor in energy conversion by depleted chromatophores of Rhodospirillum rubrum.", "content": "Role of photophosphorylation coupling factor in energy conversion by depleted chromatophores of Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362685"}
{"pmid": "4362686", "title": "The kinetic mechanism of glycerokinase.", "content": "The kinetic mechanism of glycerokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362686"}
{"pmid": "4362689", "title": "The structure of the heme crevice of ferric cytochrome c alkylated at methionine-80.", "content": "The structure of the heme crevice of ferric cytochrome c alkylated at methionine-80.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362689"}
{"pmid": "4362688", "title": "The specificity of chromium nucleotides as inhibitors of selected kinases.", "content": "The specificity of chromium nucleotides as inhibitors of selected kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362688"}
{"pmid": "4362690", "title": "Alkaline isomerization of oxidized cytochrome c. Equilibrium and kinetic measurements.", "content": "Alkaline isomerization of oxidized cytochrome c. Equilibrium and kinetic measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362690"}
{"pmid": "4362692", "title": "Effect of cAMP on nucleoside metabolism. I. Effect on thymidine transport and incorporation in monkey cells (CV-1).", "content": "Effect of cAMP on nucleoside metabolism. I. Effect on thymidine transport and incorporation in monkey cells (CV-1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362692"}
{"pmid": "4362691", "title": "Primary epithelioid sarcoma of the hand and forearm. A review of thirteen cases.", "content": "Primary epithelioid sarcoma of the hand and forearm. A review of thirteen cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362691"}
{"pmid": "4362693", "title": "The role of humoral factors in the regression of leukemia in chickens as measured by in vitro colony formation.", "content": "The role of humoral factors in the regression of leukemia in chickens as measured by in vitro colony formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362693"}
{"pmid": "4362694", "title": "Inhibition of development of transformation by Rous sarcoma virus in cultures of high cell density.", "content": "Inhibition of development of transformation by Rous sarcoma virus in cultures of high cell density.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362694"}
{"pmid": "4362695", "title": "Viral probe into the events of cellular (in vitro) aging.", "content": "Viral probe into the events of cellular (in vitro) aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362695"}
{"pmid": "4362696", "title": "Pyrimidine excretion by cultured fibroblasts: effect of mutational deficiency in pyrimidine salvage enzymes.", "content": "Pyrimidine excretion by cultured fibroblasts: effect of mutational deficiency in pyrimidine salvage enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362696"}
{"pmid": "4362698", "title": "A new rapid method for estimation of urinary pregnanediol.", "content": "A new rapid method for estimation of urinary pregnanediol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362698"}
{"pmid": "4362687", "title": "The inhibition of acetate, pyruvate, and 3-phosphogylcerate kinases by chromium adenosine triphosphate.", "content": "The inhibition of acetate, pyruvate, and 3-phosphogylcerate kinases by chromium adenosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362687"}
{"pmid": "4362699", "title": "Proceedings: Release of adrenocorticotrophin from the isolated pituitary gland of the rat: studies with theophylline.", "content": "Proceedings: Release of adrenocorticotrophin from the isolated pituitary gland of the rat: studies with theophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362699"}
{"pmid": "4362697", "title": "The influence of sex steroids on calcium- and magnesium-induced mitogenesis in isolated rat thymic lymphocytes.", "content": "The influence of sex steroids on calcium- and magnesium-induced mitogenesis in isolated rat thymic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362697"}
{"pmid": "4362701", "title": "Lower motor neuron degeneration associated with type C RNA virus infection in mice: neuropathological features.", "content": "Lower motor neuron degeneration associated with type C RNA virus infection in mice: neuropathological features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362701"}
{"pmid": "4362700", "title": "Ultrastructural studies of the dying-back process. I. Peripheral nerve terminal and axon degeneration in systemic acrylamide intoxication.", "content": "Ultrastructural studies of the dying-back process. I. Peripheral nerve terminal and axon degeneration in systemic acrylamide intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362700"}
{"pmid": "4362702", "title": "Lipogenesis and insulin sensitivity of single fat cells.", "content": "Lipogenesis and insulin sensitivity of single fat cells. 1. A method for measuring the lipogenesis from [(14)C]glucose by single fat cells is described: (i) after incubation with ;carrier-free' [U-(14)C]glucose (0.55 mu-mole/ml.), collagenase-isolated fat cells were fixed with osmium tetroxide; (ii) similarly incubated pieces of epididymal fat pads were treated with osmium tetroxide for 90 sec, whereby only the superficial cells are fixed, and the tissue was then disintegrated by shaking with collagenase. The osmium-fixed free cells were washed, sucked into a micropipette, measured under a microscope and assayed individually for (14)C-activity.2. There was a quantitative recovery of (14)C-lipid activity from osmium-fixed single cells.3. Both collagenase-isolated cells and in situ fixed surface cells were normally distributed with respect to diameters (for both cell groups from ad lib. fed rats of ca. 110 g; mean diameter, about 55 mum; S.D. about 7 mum).4. Frequency distribution curves (number of fat cells versus (14)C-lipogenesis per cell) were asymmetric and very broad (coefficient of variation about 50%) for collagenase-isolated cells incubated with insulin (10(3) mu-u./ml.). Frequency distribution curves for surface cells obtained from similarly incubated pieces of epididymal fat pads showed a coefficient of variation of the same magnitude, whereas the mean lipogenesis of these cells was only about one third of that of the isolated cells.5. Collagenase-isolated cells incubated in the presence of insulin (10(3) mu-u./ml.) showed a weak but highly significant positive correlation between fat cell diameter and (14)C-lipogenesis (eight rats, r about 0.5 and P < 0.001 for each rat). Analysis of the relationship: lipogenesis = k x diameter to the exponent of beta showed that the estimates of beta varied significantly from rat to rat (range: 1.3-2.9). Similar correlations between cell size and lipogenesis were found both for cells incubated with insulin in various submaximal concentrations and for cells incubated without insulin.6. Small and large cells from the same rat were equally sensitive to insulin.7. Statistical analysis of frequency distribution curves (number of cells versus (14)C-lipogenesis per unit surface area) representing cells from the same rat incubated with insulin 0, 2.5, 5, 10, and 10(3) mu-u./ml., respectively, suggests that insulin exerts a graded influence on the lipogenesis of each fat cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362702"}
{"pmid": "4362703", "title": "Organization of corticofugal neurones in somatosensory area II of the cat.", "content": "Organization of corticofugal neurones in somatosensory area II of the cat. 1. This investigation had two main objectives: first to determine whether or not motor activity could be elicited by localized intracortical stimulation in somatosensory area II of the cat, and secondly to identify, by antidromic stimulation, neurones which projected to subcortical structures and to study their afferent input.2. Although arm movements could be elicited in most cats by intracortical train stimulation with tungsten micro-electrodes, the lowest motor thresholds were much higher than the lowest thresholds for the primary motor area under similar experimental conditions. Facial responses were evoked at lower stimulus thresholds, but the threshold decreased steadily as successive stimulation tracks approached the coronal face area. Previously observed responses to prolonged surface stimulation could have been caused by intracortical spread of excitation or by escape of stimulus to the primary area, especially the face area.3. Neurones with corticofugal axons projecting to bulbar and spinal levels were first identified by their antidromic response to stimulation of the cerebral peduncle. Each was further tested by stimulation of the cervical corticospinal tract, and the dorsal column nuclei. Their receptive fields were then recorded.4. It was possible to classify the neurones into four main categories: (i) non-descending neurones: neurones not activated antidromically by any of the subcortical stimulating electrodes. The majority of these neurones had very small (lemniscal type) receptive fields, (ii) corticobulbar neurones: these were invaded antidromically by stimulation of the peduncle but not by spinal or dorsal column nuclei stimulation. They had ;stocking-like' or larger receptive fields; (iii) cortico-spinal neurones: neurones driven antidromically by stimulation of corticospinal fibres. Characteristically, these neurones had large confluent fields, often bilateral. Very few had receptive fields of the lemniscal type; (iv) neurones invaded by dorsal column nuclei stimulation: the number of such units was extremely low and their receptive fields were large or ;stocking-like'.5. The results indicate that somatosensory area II in the cat does not exert an independent motor control of spinal neurones, and it is thought that corticofugal neurones of SII are involved in the control of somatosensory transmission rather than having a direct motor function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362703"}
{"pmid": "4362705", "title": "The family as a system: a network of relationships.", "content": "The family as a system: a network of relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362705"}
{"pmid": "4362715", "title": "Causes of variation of copper, iron, manganese, zinc and magnesium levels in bovine livers. 1. Determination of trace elements by atomic absorption spectrophotometry.", "content": "Causes of variation of copper, iron, manganese, zinc and magnesium levels in bovine livers. 1. Determination of trace elements by atomic absorption spectrophotometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362715"}
{"pmid": "4362714", "title": "Incidence and distribution of neutralizing antibodies to porcine enteroviruses in Southern Africa.", "content": "Incidence and distribution of neutralizing antibodies to porcine enteroviruses in Southern Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362714"}
{"pmid": "4362704", "title": "The use of closed-circuit television in marital therapy.", "content": "The use of closed-circuit television in marital therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362704"}
{"pmid": "4362706", "title": "Intervention in a pathological cycle of anxiety.", "content": "Intervention in a pathological cycle of anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362706"}
{"pmid": "4362716", "title": "Editorial: Varicella-zoster infections: zoster immune globulin.", "content": "Editorial: Varicella-zoster infections: zoster immune globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362716"}
{"pmid": "4362717", "title": "Cancer of the gastrointestinal tract. Histogenesis and premalignant lesions.", "content": "Cancer of the gastrointestinal tract. Histogenesis and premalignant lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362717"}
{"pmid": "4362709", "title": "International trends: how to manage health--a summary of WHO technical discussions.", "content": "International trends: how to manage health--a summary of WHO technical discussions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362709"}
{"pmid": "4362718", "title": "Cancer of the gastrointestinal tract. Diagnostic radiology.", "content": "Cancer of the gastrointestinal tract. Diagnostic radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362718"}
{"pmid": "4362707", "title": "The role of the nurse in counseling the alcoholic.", "content": "The role of the nurse in counseling the alcoholic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362707"}
{"pmid": "4362711", "title": "Speaking out on: increasing costs and reducing patient care in the name of patient protection or standards.", "content": "Speaking out on: increasing costs and reducing patient care in the name of patient protection or standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362711"}
{"pmid": "4362710", "title": "Strategies for interviewing in language and thought disorders.", "content": "Strategies for interviewing in language and thought disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362710"}
{"pmid": "4362720", "title": "In vitro antimicrobial susceptibility testing. Clinical implications and limitations.", "content": "In vitro antimicrobial susceptibility testing. Clinical implications and limitations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362720"}
{"pmid": "4362708", "title": "The process of implementing the nurse's role in a neighborhood center.", "content": "The process of implementing the nurse's role in a neighborhood center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362708"}
{"pmid": "4362719", "title": "Untoward effects of antimicrobial agents on major organ systems.", "content": "Untoward effects of antimicrobial agents on major organ systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362719"}
{"pmid": "4362712", "title": "Psychiatric drugs and trends; new regulations on vitamins and minerals.", "content": "Psychiatric drugs and trends; new regulations on vitamins and minerals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362712"}
{"pmid": "4362722", "title": "Viral infections of the central nervous system.", "content": "Viral infections of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362722"}
{"pmid": "4362721", "title": "Antimicrobial drugs for treatment of infections caused by aerobic gram-negative bacilli.", "content": "Antimicrobial drugs for treatment of infections caused by aerobic gram-negative bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362721"}
{"pmid": "4362724", "title": "The enhancement by caffeine of alkylation-induced cell death, mutations and chromosomal aberrations in Chinese hamster cells, as a result of inhibition of post-replication DNA repair.", "content": "The enhancement by caffeine of alkylation-induced cell death, mutations and chromosomal aberrations in Chinese hamster cells, as a result of inhibition of post-replication DNA repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362724"}
{"pmid": "4362723", "title": "New antituberculosis drugs and concepts of prophylaxis.", "content": "New antituberculosis drugs and concepts of prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362723"}
{"pmid": "4362713", "title": "Geriatrics: CPI consumer price index.", "content": "Geriatrics: CPI consumer price index.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362713"}
{"pmid": "4362725", "title": "Translation of collagen mRNA from chick embryo calvaria in a cell-free system derived from Krebs II ascites cells.", "content": "Translation of collagen mRNA from chick embryo calvaria in a cell-free system derived from Krebs II ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362725"}
{"pmid": "4362728", "title": "Fertility control by intrauterine release of progesterone.", "content": "Fertility control by intrauterine release of progesterone. The contraceptive effectiveness of small amounts of progesterone released in the uterine cavity via a silastic progesterone T IUD was studied.  Over 1600 woman-months of use in 249 women were evaluated.  The amount of progesterone remaining in 14 capsules revoved 161-200 days after insertion was variable, indicating a possible effect of individual uterine environment on release rates.  No pregnancies occurred while devices releasing adequate amounts of progesterone were in situ.  7.9% of the devices were displaced or expelled.  Serial plasma hormonal determinations showed no differences between patients with inert and progesterone IUDs.  There was no inhibition of ovulation or change in cervical mucus.  The mechanism of action is probably related to the decidual changes induced in the endometrial receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362728"}
{"pmid": "4362727", "title": "Effect of exogenous conjugated estrogen on plasma gonadotropins and ovarian steroids during the menstrual cycle.", "content": "Effect of exogenous conjugated estrogen on plasma gonadotropins and ovarian steroids during the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362727"}
{"pmid": "4362729", "title": "Demonstration of a defect in the formation of adenosine 3',5'-monophosphate in vasopressin-resistant diabetes insipidus.", "content": "Demonstration of a defect in the formation of adenosine 3',5'-monophosphate in vasopressin-resistant diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362729"}
{"pmid": "4362730", "title": "Adenylate cyclase activity in immature rabbit lung.", "content": "Adenylate cyclase activity in immature rabbit lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362730"}
{"pmid": "4362731", "title": "Treatment of precocious puberty with cyproterone acetate.", "content": "Treatment of precocious puberty with cyproterone acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362731"}
{"pmid": "4362732", "title": "Etiologic and epidemiologic investigations on the incidence of viral infections in two children communities during the period 1970-1971.", "content": "Etiologic and epidemiologic investigations on the incidence of viral infections in two children communities during the period 1970-1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362732"}
{"pmid": "4362733", "title": "Interferon production by lymphocytes in human milk.", "content": "Interferon production by lymphocytes in human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362733"}
{"pmid": "4362736", "title": "A simple fluorimetric microassay for adenine compounds in platelets and plasma and its application to studies on the platelet release reaction.", "content": "A simple fluorimetric microassay for adenine compounds in platelets and plasma and its application to studies on the platelet release reaction. 1. The formation of a stable fluorescent product between chloroacetaldehyde and adenine or its derivatives provides the basis of a rapid simple assay for total adenine compounds in blood platelets and in plasma. The assay will measure down to 200pmol of adenine nucleotides. An evaluation of the method established the optimum conditions for the production of maximum fluorescence. 2. Values obtained for total adenine compounds in platelets were 12.9nmol/10(8) cells in man and 7.8nmol/10(8) cells in rat. These closely agree with previous values for total platelet adenine nucleotides found by using a firefly luciferase assay, or a recycled NAD-linked photometric assay. This supports the concept that the chloroacetaldehyde reaction measures total adenine nucleotides in platelets. 3. Platelet aggregation induced by collagen was studied photometrically in 0.1ml volumes of citrated platelet-rich plasma, and total adenine nucleotides were assayed in platelets and plasma before and after aggregation. During aggregation 58% of adenine nucleotides were released from human platelets, and 36% from rat platelets. 4. The chloroacetaldehyde assay is no substitute for more sophisticated procedures, but is a simple sensitive means of monitoring the release of adenine nucleotides from blood platelets and is particularly valuable when small plasma samples must be used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362736"}
{"pmid": "4362738", "title": "Fate of corticotrophins in an isolated adrenal-cell bioassay and decrease of peptide breakdown by cell purification.", "content": "Fate of corticotrophins in an isolated adrenal-cell bioassay and decrease of peptide breakdown by cell purification. 1. The fate of corticotrophins in a trypsin-dispersed rat adrenal-cell assay system was investigated with a view to establishing whether differences in the rate of inactivation might contribute to potency differences observed between analogues. 2. Corticotrophin-(1-24)-tetracosapeptide and to a lesser extent synthetic 1-39 corticotrophins were found to be inactivated during incubation with cell suspension. 3. Peptide fragments were isolated by using [[(3)H(2)]Tyr(23)]corticotrophin-(1-24)- tetracosapeptide as a marker. The fragments indicate a peptidase with a predominantly tryptic specificity. 4. The peptidase is present in the extracellular fluid and is released from cells when they are damaged. 5. Cells were fractionated on an albumin gradient. Cells from the zona fasciculata and the zona intermedia or reticularis were present in fractions which produced fluorogenic steroids in response to corticotrophin. 6. Purification of the cells by centrifugation through albumin decreased degradation by peptidases, so that if the assay is carried out with a dilute suspension of purified cells peptide breakdown should not affect the observed potencies of adrenocorticotrophin analogues. 7. No binding of [[(3)H(2)]Tyr(23)]corticotrophin-(1-24)- tetracosapeptide to cells could be detected at low concentrations of the peptide. This indicated that less than 120 receptors/cell are occupied during stimulation by a dose that would elicit approx. 80% of the maximal response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362738"}
{"pmid": "4362737", "title": "The detection and characterization by electron-paramagnetic-resonance spectroscopy of iron-sulphur proteins and other electron-transport components in chromatophores from the purple bacterium Chromatium.", "content": "The detection and characterization by electron-paramagnetic-resonance spectroscopy of iron-sulphur proteins and other electron-transport components in chromatophores from the purple bacterium Chromatium. Low-temperature e.p.r. (electron-paramagnetic-resonance) spectroscopy was used to detect electron-transport components in Chromatium chromatophores with e.p.r. signals in the g=2.00 region. High-potential iron protein (E(m8.0)=+325mV, where E(m8.0) is the midpoint potential at pH8) and a second component (g=1.90, E(m8.0)=+285mV) are oxidized in illuminated chromatophores. Two iron-sulphur proteins (g=1.94) with E(m8.0)=-290mV and E(m8.0)=-50mV are present. One (E(m8.0)=-50mV) is reduced on illumination. A component (g=1.82) with E(m8.0)=-135mV is photoreduced at 10 degrees K. The midpoint potential of this component is altered by o-phenanthroline and pH. The properties of this component suggest that it is the primary electron acceptor of a photochemical system. Another component (g=1.98) also has some of the properties of a primary electron acceptor, but its function cannot be completely defined. These results show that iron-sulphur proteins are present in the electron-transport system of Chromatium and indicate their role in electron transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362737"}
{"pmid": "4362739", "title": "A protein kinase inhibitor in brown adipose tissue of developing rats.", "content": "A protein kinase inhibitor in brown adipose tissue of developing rats. A heat-stable protein was extracted from brown adipose tissue of infant rats that inhibited both purified bovine heart protein kinase and a crude preparation of protein kinase from brown fat. It did not act as an adenosine triphosphatase nor did it exert its effect by proteolytic action. Inhibition of protein kinase was affected in both the presence and the absence of cyclic AMP. Most of the inhibitory activity was present in the 100000g supernatant fraction of tissue homogenates. Inhibitory activity was highest perinatally and it declined 10 days after birth. It is suggested that the protein kinase inhibitor may play a role in regulating cyclic AMP actions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362739"}
{"pmid": "4362740", "title": "The development of cytochromes during the cell cycle of a glucose-repressed fission yeast, Schizosaccharomyces pombe 972h-.", "content": "The development of cytochromes during the cell cycle of a glucose-repressed fission yeast, Schizosaccharomyces pombe 972h-. 1. Spectrophotometric analysis of intact cells of Schizosaccharomyces pombe, harvested from exponentially growing cultures during the phase of glucose repression, revealed the presence of cytochromes a+a(3), c and at least two species of cytochrome b. 2. An absorption maximum at 554nm at 77 degrees K, previously attributed to cytochrome c(1), has been identified as a b-type cytochrome. 3. CO-difference spectra reveal the presence of cytochromes P-420 and P-450 in addition to cytochrome a(3). 4. The cell cycle was analysed by separation of cells into classes representing successive stages in the cell cycle by isopycnic zonal centrifugation. 5. Cytochromes c(548), b(554) and b(560) each exhibited a single broad maximum of synthesis during the cell cycle. 6. Amounts of cytochromes a+a(3) and b(563) (tentatively identified as cytochrome b(T) by its reaction on pulsing anaerobic cell suspensions with O(2)) oscillated in phase, and showed two maxima during the cycle; the second maximum of cytochromes a+a(3) was coincident with a maximum of activity of enzymically active cytochrome c oxidase. 7. The amount of cytochrome P-420 decreased during the first three-quarters of the cell-cycle, whereas that of cytochrome P-450 increased during this period. 8. The discrepancy between spectrophotometric and enzymic assay of cytochrome c oxidase, the changing ratio of cytochrome a(3)/cytochrome a and the relationship between changes in cellular content of cytochromes and previous observations on respiratory oscillations during the cell cycle are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362740"}
{"pmid": "4362741", "title": "Oxidative decarboxylation of glycollate and glyoxylate by leaf peroxisomes.", "content": "Oxidative decarboxylation of glycollate and glyoxylate by leaf peroxisomes. 1. The conditions under which peroxisomal preparations from leaves of spinach beet and spinach catalyse the release of (14)CO(2) from [1-(14)C]glycollate and [1-(14)C]glyoxylate were investigated. 2. At pH8, (14)CO(2) production from [1-(14)C]glyoxylate was accompanied by equivalent quantities of formate. The accumulation of oxalate and the effects of various reagents, especially catalase inhibitors, show that glyoxylate is non-enzymically oxidized by H(2)O(2), which is generated by the oxidation of glyoxylate to oxalate by the action of glycollate oxidase. 3. (14)CO(2) is shown to be generated from [1-(14)C]glycollate at pH8 by a similar reaction, but the H(2)O(2) is generated mainly by the oxidation of glycollate to glyoxylate. 4. The physiological significance of these reactions is discussed, with special reference to their role in photorespiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362741"}
{"pmid": "4362742", "title": "Accumulation of lanthanum by rat liver mitochondria.", "content": "Accumulation of lanthanum by rat liver mitochondria. The interaction of La(3+) with rat liver mitochondria was examined with a wide variety of techniques permitting measurement of respiratory and structural responses. It is concluded that La(3+) is accumulated by mitochondria in a process that is at least partially energy-dependent, and is bound with quite high affinity to membrane-associated sites both external and internal to the inner membrane. The relative insensitivity of the accumulation process to respiratory inhibitors and to the permeant anion acetate has interesting implications for the mechanism of active cation transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362742"}
{"pmid": "4362743", "title": "Microbial metabolism of amino alcohols. Aminoacetone metabolism via 1-aminopropan-2-ol in Pseudomonas sp. N.C.I.B. 8858.", "content": "Microbial metabolism of amino alcohols. Aminoacetone metabolism via 1-aminopropan-2-ol in Pseudomonas sp. N.C.I.B. 8858. 1. Pseudomonas sp. N.C.I.B. 8858 grew well on d- and l-1-aminopropan-2-ol and on aminoacetone. 2. Cell-free extracts possessed high activities of inducibly formed l-1-aminopropan-2-ol-NAD(+) oxidoreductase, amino alcohol-ATP phosphotransferase, dl-1-aminopropan-2-ol O-phosphate phospho-lyase and aldehyde-NAD(+) oxidoreductase, but no 1-aminopropan-2-ol racemase or d-1-aminopropan-2-ol-NAD(+) oxidoreductase. 3. The amino alcohol kinase (activated by ADP) was non-stereospecific towards 1-aminopropan-2-ol and was one-third as active with ethanolamine. The phospho-lyase was active with l- and d-1-aminopropan-2-ol O-phosphate, but ethanolamine O-phosphate was only one-tenth as active as its higher homologues. The purified aldehyde dehydrogenase was active with propionaldehyde, acetaldehyde and also with methylglyoxal. The previously observed 2-oxo aldehyde dehydrogenase activity was considered to be due to the broadly specific aldehyde dehydrogenase. 4. Mutants of Pseudomonas sp. N.C.I.B. 8858 deficient in 1-aminopropan-2-ol kinase, 1-aminopropan-2-ol O-phosphate phospho-lyase, aldehyde dehydrogenase or an enzyme involved in propionate metabolism were incapable of growth on aminoacetone or 1-aminopropan-2-ol as carbon source, although all except the kinase- or phospho-lyasedeficient mutants could use these compounds and ethanolamine as nitrogen sources. The aldehyde dehydrogenase-deficient mutants produced copious amounts of propionaldehyde and acetaldehyde during growth on the corresponding amino alcohols. 5. The path of aminoacetone metabolism in Pseudomonas sp. N.C.I.B. 8858 was concluded to involve l-1-aminopropan-2-ol, the O-phosphate ester of this compound, propionaldehyde and propionate as obligatory intermediates. d-1-Aminopropan-2-ol was metabolized by the same route as the l-isomer, gratuitously inducing formation of the stereospecific l-1-aminopropan-2-ol dehydrogenase. 6. Extracts of the pseudomonad grown with ethanolamine as the nitrogen source were devoid of 1-aminopropan-2-ol dehydrogenase, the kinase and the phospho-lyase, but exhibited cobamide coenzyme-dependent deaminase activity. Mutants deficient in kinase or phospho-lyase (deaminating) grew well on ethanolamine as the nitrogen source. Ethanolamine deaminase was inactive with, but inhibited by, 1-aminopropan-2-ol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362743"}
{"pmid": "4362744", "title": "The involvement of endogenous dolichol in the formation of lipid-linked precursors of glycoprotein in rat liver.", "content": "The involvement of endogenous dolichol in the formation of lipid-linked precursors of glycoprotein in rat liver. Endogenous dolichol was shown to function as a natural acceptor of mannose residues by using regenerating rat liver containing [(3)H]dolichol. When subcellular fractions from this liver were incubated with GDP-[(14)C]mannose a double-labelled lipid, which represented 30% of the total [(14)C]mannolipid, could be isolated. This lipid was shown to be identical with the dolichol phosphate mannose formed from exogenous dolichol phosphate, by chromatography, stability to alkali and by chemical cleavage to mannose and dolichol derivatives. It was formed by the rough endoplasmic reticulum and mitochondria. If it is concerned in glycoprotein synthesis this would suggest that it functions in the formation of both secreted and mitochondrial glycoproteins. When both the dolichol and retinol of rat tissue were radioactive they made similar contributions to the synthesis of the lipid by liver microsomal fractions and intestinal epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362744"}
{"pmid": "4362746", "title": "Effects of collagen and of aspirin on the concentration of guanosine 3':5'-cyclic monophosphate in human blood platelets: measurement by a prelabelling technique.", "content": "Effects of collagen and of aspirin on the concentration of guanosine 3':5'-cyclic monophosphate in human blood platelets: measurement by a prelabelling technique. A method is described for isolating cyclic [(3)H]GMP from platelets preincubated with [(3)H]guanine. Collagen increased and aspirin decreased the cyclic [(3)H]GMP concentration in platelets. The results are consistent with a role for cyclic GMP in the platelet release reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362746"}
{"pmid": "4362748", "title": "Triethylcholine inhibition of phosphatidylcholine synthesis in synaptosomes and mouse leukemic cells L1210 and accelerated synaptosomal uptake of choline and triethylcholine in the presence of acetylcholine.", "content": "Triethylcholine inhibition of phosphatidylcholine synthesis in synaptosomes and mouse leukemic cells L1210 and accelerated synaptosomal uptake of choline and triethylcholine in the presence of acetylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362748"}
{"pmid": "4362747", "title": "Effect of phenobarbital or pregnenolone-16alpha-carbonitrile (PCN) pretreatment on acute carbon tetrachloride hepatotoxicity in rats.", "content": "Effect of phenobarbital or pregnenolone-16alpha-carbonitrile (PCN) pretreatment on acute carbon tetrachloride hepatotoxicity in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362747"}
{"pmid": "4362745", "title": "Rat brain microsomal gangliosides. Accessibility to a neuraminidase preparation and the possible existence of different pools in relation to their biosynthesis.", "content": "Rat brain microsomal gangliosides. Accessibility to a neuraminidase preparation and the possible existence of different pools in relation to their biosynthesis. 1. Treatment of rat brain microsomal membranes with a neuraminidase preparation from Clostridium perfringens resulted in an almost complete conversion of polysialogangliosides into monosialogangliosides. 2. Neuraminidase treatment of the membranes did not increase the incorporation of N-[(3)H]acetylneuraminic acid from CMP-N-[(3)H]acetylneuraminic acid into the gangliosidic fraction, indicating that a monosialoganglioside is an acceptor of N-acetylneuraminic acid in these membranes only if, in addition to having the right chemical structure, it is in a proper position, probably in relation to the endogenous sialyltransferases. 3. These experiments also indicated that no independent turnover of the neuraminidase-labile N-acetylneuraminyl groups of gangliosides occurred in vitro. 4. N-[(3)H]Acetylneuraminic acid from endogenous polysialogangliosides labelled in vitro was released by neuraminidase at a slower rate than N-acetylneuraminic acid from unlabelled gangliosides of the same membranes. From this it was concluded that recently synthesized polysialogangliosides (completed in vitro) are in the membranes in a position less accessible to neuraminidase than are those synthesized earlier which were present in the membranes at the start of the labelling experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362745"}
{"pmid": "4362749", "title": "Purification of human renin and inhibition of its activity by pepstatin.", "content": "Purification of human renin and inhibition of its activity by pepstatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362749"}
{"pmid": "4362750", "title": "Effect of certain metabolic regulators on the activity of lysosomal enzymes in regenerating rat liver.", "content": "Effect of certain metabolic regulators on the activity of lysosomal enzymes in regenerating rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362750"}
{"pmid": "4362754", "title": "Mesophilic clostridia in Puget Sound.", "content": "Mesophilic clostridia in Puget Sound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362754"}
{"pmid": "4362755", "title": "Stability of different viruses in a newly developed transport medium.", "content": "Stability of different viruses in a newly developed transport medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362755"}
{"pmid": "4362756", "title": "Production and control of extracellular enzymes in Micrococcus sodonensis.", "content": "Production and control of extracellular enzymes in Micrococcus sodonensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362756"}
{"pmid": "4362757", "title": "Purification and partial characterization of an antibiotic produced by Myxococcus xanthus.", "content": "Purification and partial characterization of an antibiotic produced by Myxococcus xanthus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362757"}
{"pmid": "4362758", "title": "Characterization of the nadR locus in Escherichia coli.", "content": "Characterization of the nadR locus in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362758"}
{"pmid": "4362759", "title": "Interaction of phentolamine and noradrenaline on myocardial contractility and adenyl cyclase activity.", "content": "Interaction of phentolamine and noradrenaline on myocardial contractility and adenyl cyclase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362759"}
{"pmid": "4362762", "title": "Ultrastructural changes associated with UV irradiation in the \"germinal plasm\" of Xenopus laevis.", "content": "Ultrastructural changes associated with UV irradiation in the \"germinal plasm\" of Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362762"}
{"pmid": "4362763", "title": "Some aspects of the behavior of young and adult rats treated with p-chlorophenylalanine in infancy.", "content": "Some aspects of the behavior of young and adult rats treated with p-chlorophenylalanine in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362763"}
{"pmid": "4362765", "title": "Murine reticulum cell neoplasms type B (Hodgkin's-like lesions) induced in BALB-c mice with field isolates of murine leukemia virus.", "content": "Murine reticulum cell neoplasms type B (Hodgkin's-like lesions) induced in BALB-c mice with field isolates of murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362765"}
{"pmid": "4362764", "title": "Formation of lithogenic bile in man.", "content": "Formation of lithogenic bile in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362764"}
{"pmid": "4362766", "title": "Acceptor control ratio of mitochondria. Factors affecting it in Morris hepatoma 5123 and Yoshida hepatoma AH-130.", "content": "Acceptor control ratio of mitochondria. Factors affecting it in Morris hepatoma 5123 and Yoshida hepatoma AH-130.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362766"}
{"pmid": "4362767", "title": "Letter: Serum dopamine-beta-hydroxylase activity in patients with leukemia and in patients with hepatoma.", "content": "Letter: Serum dopamine-beta-hydroxylase activity in patients with leukemia and in patients with hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362767"}
{"pmid": "4362769", "title": "Conjugation of enzymes to anti-poliovirus globulin: effect of enzyme molecular weight on virus neutralization capacity.", "content": "Conjugation of enzymes to anti-poliovirus globulin: effect of enzyme molecular weight on virus neutralization capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362769"}
{"pmid": "4362770", "title": "The enhanced immogenicity of horse cytochrome C by light dinitrophenylation.", "content": "The enhanced immogenicity of horse cytochrome C by light dinitrophenylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362770"}
{"pmid": "4362771", "title": "Retention of significant antibody binding by surface antigens of feline leukemia cells (FLA) after fixation with formaldehyde and glutaraldehyde.", "content": "Retention of significant antibody binding by surface antigens of feline leukemia cells (FLA) after fixation with formaldehyde and glutaraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362771"}
{"pmid": "4362772", "title": "Control of interferon, migration inhibition factor, and expression of virus capsid antigens in Burkitt's lymphoma-derived cell lines: role of L-arginine.", "content": "Control of interferon, migration inhibition factor, and expression of virus capsid antigens in Burkitt's lymphoma-derived cell lines: role of L-arginine. The effects of an arginine-utilizing mycoplasma, Mycoplasma arginini, and of varying levels of arginine in the growth media of the Epstein-Barr virus (EBV)-containing EB1 and EB3 cell lines, and the EBV-free RPMI 1788 cell line, were studied. l-Arginine, at a concentration of 0.1 mM in the growth medium, led to a reduction of the EBV capsid antigen content of the EB1 and EB3 cells lines as determined by indirect immunofluorescence, and M. arginini infection enhanced this reduction. The synthesis of two immune products, interferon and macrophage migration inhibition factor, was enhanced by growing the cell lines in medium containing arginine at a concentration of 0.1 mM, but the RPMI 1788 cell line produced much less of both products than EB1 or EB3 under these conditions. Infection of the cell lines with M. arginini reduced the amount of interferon produced and completely inhibited macrophage migration inhibition factor synthesis. The addition of arginine to a final concentration of 0.6 mM in the growth medium caused a dual effect: the EB1 and EB3 cell lines maintained the original level of EBV capsid antigens, even when infected with M. arginini; immune product synthesis was greatly reduced or completely inhibited by the addition of arginine, and M. arginini infection caused no further reduction of immune product synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362772"}
{"pmid": "4362773", "title": "Cytomegalovirus interference in vitro.", "content": "Cytomegalovirus interference in vitro. Cytomegalovirus (CMV) was shown to induce a state of viral interference in human embryo fibroblast cultures (HEF). This interference was characterized by: (i) requirement for infectious virus; (ii) a latent period (48 to 96 h) for establishment of the interference; (iii) activity against a representative group of heterologous viruses; (iv) loss of interfering activity when challenged with a high multiplicity of infection; (v) lack of effect on adsorption of virus; (vi) mediation by a soluble product of CMV-cell interaction that it is not blocked by anti-CMV antibody; and (vii) absence of detectable interferon, although the soluble mediator shares a number of characteristics with interferon. This state of interference in HEF cultures could be simulated by extended exposure to subdetectable levels of human interferon. It is postulated that CMV induced the production of a soluble, interferon-like mediator of viral interference and that continuous exposure of the HEF culture to this mediator resulted in the development of resistance to a number of heterologous viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362773"}
{"pmid": "4362774", "title": "A new method for the investigation of the capture reaction in phosphatase cytochemistry. 3. Effects of the composition of the incubation medium on the trapping of phosphate ions in a model system.", "content": "A new method for the investigation of the capture reaction in phosphatase cytochemistry. 3. Effects of the composition of the incubation medium on the trapping of phosphate ions in a model system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362774"}
{"pmid": "4362775", "title": "Alleged rape. An invitational symposium.", "content": "Alleged rape. An invitational symposium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362775"}
{"pmid": "4362776", "title": "Analogs of cyclic AMP and cyclic GMP: general methods of synthesis and the relationship of structure to enzymic activity.", "content": "Analogs of cyclic AMP and cyclic GMP: general methods of synthesis and the relationship of structure to enzymic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362776"}
{"pmid": "4362778", "title": "Effects of ethanol on gastric mucosal adenosine 3', 5' monophosphate (cAMP).", "content": "Effects of ethanol on gastric mucosal adenosine 3', 5' monophosphate (cAMP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362778"}
{"pmid": "4362777", "title": "The neuroendocrinology of human sleep.", "content": "The neuroendocrinology of human sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362777"}
{"pmid": "4362779", "title": "Protein and polypeptide hormones as inhibitors.", "content": "Protein and polypeptide hormones as inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362779"}
{"pmid": "4362784", "title": "The Montefiore Hospital after-care program.", "content": "The Montefiore Hospital after-care program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362784"}
{"pmid": "4362785", "title": "Isoniazid as a cause of neuropathy and sideroblastic anaemia.", "content": "Isoniazid as a cause of neuropathy and sideroblastic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362785"}
{"pmid": "4362787", "title": "Triglyceride storage disease. A group of inborn errors of triglyceride metabolism.", "content": "Triglyceride storage disease. A group of inborn errors of triglyceride metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362787"}
{"pmid": "4362786", "title": "Familial lipoatrophic diabetes with dominant transmission. A new syndrome.", "content": "Familial lipoatrophic diabetes with dominant transmission. A new syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362786"}
{"pmid": "4362789", "title": "Reconstruction of the trachea. Experience in 100 consecutive cases.", "content": "Reconstruction of the trachea. Experience in 100 consecutive cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362789"}
{"pmid": "4362790", "title": "Occurrence of precipitating antibodies to bluetongue virus in sera of farm animals in Iran.", "content": "Occurrence of precipitating antibodies to bluetongue virus in sera of farm animals in Iran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362790"}
{"pmid": "4362800", "title": "Homozygous familial hypercholesterolemia: specificity of the biochemical defect in cultured cells and feasibility of prenatal detection.", "content": "Homozygous familial hypercholesterolemia: specificity of the biochemical defect in cultured cells and feasibility of prenatal detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362800"}
{"pmid": "4362801", "title": "Gene frequencies of erythrocytic enzymes of Alaskan Eskimos and Athabaskan Indians.", "content": "Gene frequencies of erythrocytic enzymes of Alaskan Eskimos and Athabaskan Indians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362801"}
{"pmid": "4362803", "title": "Effects of dibutyryl cyclic AMP on alpha-methyl-d-glucoside accumulation in rabbit kidney.", "content": "Effects of dibutyryl cyclic AMP on alpha-methyl-d-glucoside accumulation in rabbit kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362803"}
{"pmid": "4362804", "title": "Initiation of transcription by RNA polymerases of Escherichia coli and phage T3.", "content": "Initiation of transcription by RNA polymerases of Escherichia coli and phage T3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362804"}
{"pmid": "4362805", "title": "Studies on the transcription of simian virus 40 and adenovirus type 2.", "content": "Studies on the transcription of simian virus 40 and adenovirus type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362805"}
{"pmid": "4362802", "title": "Neurogenic pressor response due to mesencephalic electrical stimulation--effect of blockade of renin-angiotensin system.", "content": "Neurogenic pressor response due to mesencephalic electrical stimulation--effect of blockade of renin-angiotensin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362802"}
{"pmid": "4362806", "title": "Termination and antitermination in transcription: control of gene expression.", "content": "Termination and antitermination in transcription: control of gene expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362806"}
{"pmid": "4362807", "title": "Control of transcription in Bacillus brevis by small molecules.", "content": "Control of transcription in Bacillus brevis by small molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362807"}
{"pmid": "4362808", "title": "Transcription of double-stranded viral and cellular DNAs by purified mammalian DNA-dependent RNA polymerases.", "content": "Transcription of double-stranded viral and cellular DNAs by purified mammalian DNA-dependent RNA polymerases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362808"}
{"pmid": "4362811", "title": "Picrotoxin antagonism of gamma-aminobutyric acid inhibitory responses and synaptic inhibition in the rat substantia nigra.", "content": "Picrotoxin antagonism of gamma-aminobutyric acid inhibitory responses and synaptic inhibition in the rat substantia nigra. Neurones in the substantia nigra of the rat, anaesthetized with urethane, are inhibited both by electrical stimulation of the ipsilateral caudate nucleus and by iontophoretically applied gamma-aminobutyric acid (GABA). Iontophoretically applied picrotoxin reversibly blocks both of these inhibitory responses. These results are consistent with the hypothesis that GABA is the transmitter released by the inhibitory striato-nigral pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362811"}
{"pmid": "4362810", "title": "(3H)-adenosine nucleotide and (3H)-noradrenaline uptake by cold stored guinea-pig taenia caecum; mechanical effects and release of (3H)-adenosine nucleotide by noradrenaline, papaverine, and nitroglycerine.", "content": "(3H)-adenosine nucleotide and (3H)-noradrenaline uptake by cold stored guinea-pig taenia caecum; mechanical effects and release of (3H)-adenosine nucleotide by noradrenaline, papaverine, and nitroglycerine. 1. Cold storage (2 degrees C) treatment progressively reduced noradrenaline uptake by the taenia caecum of the guinea-pig. After 15 days of cold treatment, [(3)H]-noradrenaline uptake by tissue was reduced to about 10% of control. On the other hand, prolonged cold storage failed to decrease [(3)H]-adenosine uptake by the taenia caecum.2. Cocaine (10 muM) inhibited noradrenaline uptake by about 82% but nucleoside uptake was inhibited by 20%. Cocaine treatment failed to decrease the residual noradrenaline uptake in the cold stored strips (more than 10 days). Phenoxybenzamine (1 muM) or oligomycin (1 mug/ml) treatment decreased the tissue adenosine uptake to about 34% and 28% of the respective controls.3. Based on thin layer chromatography, it was estimated that approximately 68% of [(3)H]-adenosine was converted into and retained as [(3)H]-ATP in the fresh tissues, a small fraction was accountable as [(3)H]-adenosine (18%) but virtually no [(3)H]-AMP, [(3)H]-cyclic AMP or [(3)H]-ADP was detected. Similar distribution of radioactivity of nucleotides was observed in tissues cold stored for 8 days.4. The inhibition of the mechanical activity of taenia by noradrenaline (10 muM), papaverine (100 muM) and nitroglycerine (100 muM) was accompanied by [(3)H]-adenine nucleotide but not [(3)H]-noradrenaline release. Treatment with phentolamine and propranolol (both 1 muM) had no effect on the adenine nucleotide release elicited by nicotine and electrical field stimulation, whereas such treatment reduced the inhibitory action of both stimuli.5. These results suggest that the nucleotide release after application of electrical and chemical stimulation may be from an extraneurogenic source. Thus, we conclude that ATP or a related nucleotide is not the chemical transmitter of the non-adrenergic inhibition in the taenia caecum of the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362810"}
{"pmid": "4362812", "title": "Study on the propagation of Herpes simplex virus (type 2) into the brain after intraocular injection.", "content": "Study on the propagation of Herpes simplex virus (type 2) into the brain after intraocular injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362812"}
{"pmid": "4362813", "title": "Brain stem-thalamus reciprocal influences in the cat.", "content": "Brain stem-thalamus reciprocal influences in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362813"}
{"pmid": "4362815", "title": "Three modes of repetitive firing and the role of threshold time course between spikes.", "content": "Three modes of repetitive firing and the role of threshold time course between spikes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362815"}
{"pmid": "4362816", "title": "A frequency shift in the hippocampal theta activity: an electrical correlate of central action of ACTH analogues in the dog?", "content": "A frequency shift in the hippocampal theta activity: an electrical correlate of central action of ACTH analogues in the dog?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362816"}
{"pmid": "4362818", "title": "Influence of dichloromethylene diphosphonate (Cl2MDP) and calcitonin on bone resorption, lactate production and phosphatase and pyrophosphatase content of mouse calvaria treated with parathyroid hormone in vitro.", "content": "Influence of dichloromethylene diphosphonate (Cl2MDP) and calcitonin on bone resorption, lactate production and phosphatase and pyrophosphatase content of mouse calvaria treated with parathyroid hormone in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362818"}
{"pmid": "4362819", "title": "Letter: Narcolepsy.", "content": "Letter: Narcolepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362819"}
{"pmid": "4362820", "title": "Arteriography in tumors of the orbit.", "content": "Arteriography in tumors of the orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362820"}
{"pmid": "4362822", "title": "Transjugular liver biopsy and cholangiography.", "content": "Transjugular liver biopsy and cholangiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362822"}
{"pmid": "4362841", "title": "The determination of age of yearling beef cattle at post-mortem by subjective appraisals of bone and muscle development.", "content": "The determination of age of yearling beef cattle at post-mortem by subjective appraisals of bone and muscle development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362841"}
{"pmid": "4362843", "title": "Developmental aspects of glucose and VFA metabolism in the germfree and conventional ruminant.", "content": "Developmental aspects of glucose and VFA metabolism in the germfree and conventional ruminant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362843"}
{"pmid": "4362842", "title": "Characterization of enzyme and metabolic patterns in mice selected for rapid post-weaning growth rate.", "content": "Characterization of enzyme and metabolic patterns in mice selected for rapid post-weaning growth rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362842"}
{"pmid": "4362844", "title": "Effect of angiotensin II on aldosterone secretion in the conscious rat.", "content": "Effect of angiotensin II on aldosterone secretion in the conscious rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362844"}
{"pmid": "4362846", "title": "Prolactin receptors: characteristics of the particulate fraction binding activity.", "content": "Prolactin receptors: characteristics of the particulate fraction binding activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362846"}
{"pmid": "4362845", "title": "Factors influencing the uptake of (alpha-14C)aminoisobutyric acid by rat testes.", "content": "Factors influencing the uptake of (alpha-14C)aminoisobutyric acid by rat testes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362845"}
{"pmid": "4362849", "title": "Concomitant association between high plasma levels of growth hormone and low hepatic mixed-function oxidase activity in the young rat.", "content": "Concomitant association between high plasma levels of growth hormone and low hepatic mixed-function oxidase activity in the young rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362849"}
{"pmid": "4362848", "title": "Inhibition of cartilage macromolecular synthesis by prostaglandin A.", "content": "Inhibition of cartilage macromolecular synthesis by prostaglandin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362848"}
{"pmid": "4362850", "title": "A strategy to improve patient-staff interaction in a mental health facility.", "content": "A strategy to improve patient-staff interaction in a mental health facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362850"}
{"pmid": "4362861", "title": "Effects of L-glutamine deprivation on growth of HVJ (Sendai virus) in BHK cells.", "content": "Effects of L-glutamine deprivation on growth of HVJ (Sendai virus) in BHK cells. l-Glutamine requirement for viral maturation was found in BHK-HVJ cells, a cell line of baby hamster kidney cells persistently infected with HVJ (Sendai virus). Synthesis of envelope protein in BHK-HVJ cells was markedly suppressed by deprivation of l-glutamine, whereas development of nucleocapsid (S) antigen was less affected. More detailed examination of this phenomenon was carried out by using a cytolytic system. Growth of HVJ in BHK cells cultured in media deprived of various amino acids was investigated, and omission of l-glutamine from culture medium resulted in a marked inhibitory effect on the release of infectious virus and synthesis of envelope protein, although synthesis of virus-specific RNA and nucleocapsid antigen in the cells was readily detected. When l-glutamine was restored to the culture medium, infectious virus and envelope protein could be detected. l-Glutamic acid, l-aspartic acid, or l-alanine could be substituted for l-glutamine. Effects of l-glutamine deprivation on HVJ growth in several other cells were also investigated. The growth of HVJ in the cells other than BHK and FL cells was not suppressed by lack of l-glutamine. Growth of Sindbis virus in BHK cells was also markedly retarded in the absence of l-glutamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362861"}
{"pmid": "4362851", "title": "The psychiatric nurse as the guardian of the ward atmosphere.", "content": "The psychiatric nurse as the guardian of the ward atmosphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362851"}
{"pmid": "4362857", "title": "Speaking out on: when is being generous something else?", "content": "Speaking out on: when is being generous something else?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362857"}
{"pmid": "4362858", "title": "Drugs and trends; the \"unproven\" \"proven\" drug.", "content": "Drugs and trends; the \"unproven\" \"proven\" drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362858"}
{"pmid": "4362854", "title": "The Barrie day care service; a study in partial hospitalization in a general hospital psychiatric facility.", "content": "The Barrie day care service; a study in partial hospitalization in a general hospital psychiatric facility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362854"}
{"pmid": "4362862", "title": "Polyoma viral DNA replicated as a nucleoprotein complex in close association with the host cell chromatin.", "content": "Polyoma viral DNA replicated as a nucleoprotein complex in close association with the host cell chromatin. Polyoma viral DNA is shown to be replicated in close association with the mouse cell chromatin. Two virus-specific nucleoprotein complexes, designated complex A and B, can be dissociated from the isolated chromatin by gentle homogenization in 0.5 M NaCl. Complex A contains only replicating polyoma (Py) DNA whereas complex B contains only mature Py DNA I. The results show, furthermore, that complex A, containing viral DNA in different stages of replication, and complex B are both nucleoproteins with the same buoyant density. The data presently available suggest that newly synthesized stretches of Py DNA are immediately complexed with mouse cell histones and that complex B becomes the \"core\" of progeny Py virions. These results suggested that Py-induced replication of the mouse cell chromatin may be necessary to provide replicating Py DNA with histones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362862"}
{"pmid": "4362863", "title": "Translation of mRNA from simian virus 40-infected cells into simian virus 40 capsid protein by cell-free extracts.", "content": "Translation of mRNA from simian virus 40-infected cells into simian virus 40 capsid protein by cell-free extracts. Messenger RNA was isolated from simian virus 40 (SV40)-infected and mock-infected cells by chromatography on poly(U) sepharose. When added to cell-free extracts from Chinese hamster ovary cells or rabbit reticulocytes, RNA from the infected cells, but not from mock-infected cells, stimulated synthesis of the major SV40 capsid protein. Identification of this species was done by sodium dodecyl sulfate gel electrophoresis, peptide mapping, and immunoprecipitation. The in vitro synthesized capsid protein was slightly different from virion assembled capsid protein, as shown by separation upon chromatography on hydroxylapatite and by minor differences in the peptide map.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362863"}
{"pmid": "4362852", "title": "Nurse, I need help; the school nurse's role in suicide prevention.", "content": "Nurse, I need help; the school nurse's role in suicide prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362852"}
{"pmid": "4362864", "title": "Comparison of JC and BK human papovaviruses with simian virus 40: restriction endonuclease digestion and gel electrophoresis of resultant fragments.", "content": "Comparison of JC and BK human papovaviruses with simian virus 40: restriction endonuclease digestion and gel electrophoresis of resultant fragments. JC virus was found to have a buoyant density of 1.20 g/cm(3) in linear sucrose-D(2)O and 1.35 g/cm(3) in cesium chloride isopycnic gradients. DNA extracted either from JC-infected cultures or from gradient-purified virions occupied a dense position relative to linear DNA in cesium chloride/ethidium bromide gradients, and the circular configuration of the extracted DNA was confirmed by electron microscopy, with a measured molecular weight of 2.93 x 10(6). DNA from BK virus was similarly prepared and compared to JC and to an SV40 DNA standard by digestion with restriction endonuclease preparations from Haemophilus influenzae, Haemophilus parainfluenzae, and Escherichia coli. Digests were electrophoretically analyzed on gradient polyacrylamide slab gels or agarose gels, and the three viruses were found to have distinctly different cleavage patterns by this form of analysis: JC and BK viruses were almost entirely different from SV40 and significantly different from each other. Thus, JC and BK human papovaviruses appear to be discrete new members of the papovavirus group, rather than SV40 variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362864"}
{"pmid": "4362853", "title": "Conflict within the marital dyad.", "content": "Conflict within the marital dyad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362853"}
{"pmid": "4362865", "title": "Establishment and maintenance of the interferon-induced antiviral state: studies in enucleated cells.", "content": "Establishment and maintenance of the interferon-induced antiviral state: studies in enucleated cells. Requirements for the physical presence of the cell's nucleus for the establishment and maintenance of the interferon-induced antiviral state were investigated. Enucleated chicken embryo fibroblasts were obtained by cytochalasin B treatment during centrifugation. The inhibition of vaccinia virus cytoplasmic DNA synthesis, monitored by autoradiography, was used to measure the antiviral activity resulting from interferon treatment. The antiviral state is not established in cells treated with interferon after removal of their nuclei. On the other hand, cells first treated with interferon for 6 or 12 h and then enucleated express the antiviral state. Furthermore, the antiviral state is maintained in enucleated cells for 16 h after enucleation. The antiviral state appears to be more stable in enucleates than in the residual nucleated cells found in the same cultures. Single cells of antiviral populations are found to be either fully permissive or fully restrictive to vaccinia DNA synthesis. The effect of an increasing intracellular multiplicity of infectious virus is to overcome the antiviral cell's block against viral DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362865"}
{"pmid": "4362866", "title": "Human cytomegalovirus. II. Lack of relatedness to DNA of herpes simples I and II, Epstein-Barr virus, and nonhuman strains of cytomegalovirus.", "content": "Human cytomegalovirus. II. Lack of relatedness to DNA of herpes simples I and II, Epstein-Barr virus, and nonhuman strains of cytomegalovirus. The purified DNA of human cytomegalovirus, radiolabeled in vitro, was examined for homology to Epstein-Barr virus, herpes simplex type I and II, and simian and murine cytomegalovirus DNA by DNA-DNA reassociation kinetics analyses with the S1 enzyme differential digestion technique. Cross-matching of the DNAs showed no relatedness or less than 5% detectable homology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362866"}
{"pmid": "4362855", "title": "Mental health--what is it?", "content": "Mental health--what is it?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362855"}
{"pmid": "4362856", "title": "The successful management of \"refractory\" ambulatory schizophrenic patients.", "content": "The successful management of \"refractory\" ambulatory schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362856"}
{"pmid": "4362859", "title": "Geriatrics; statistics on the population and characteristics of the elderly in the United States.", "content": "Geriatrics; statistics on the population and characteristics of the elderly in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362859"}
{"pmid": "4362867", "title": "RNA transcription by the virion polymerases of five rhabdoviruses.", "content": "RNA transcription by the virion polymerases of five rhabdoviruses. The presence of a virion-associated RNA-dependent RNA polymerase in five serologically distinct rhabdovirus isolates (vesicular stomatitis virus [VSV] Indiana, VSV New Jersey, Cocal, Chandipura, and Piry viruses) has been demonstrated. The enzyme for each virus has been shown to be a transcriptase capable of synthesizing in vitro RNA which is complementary to the viral genome. By sequence analyses it has been shown that, for each rhabdovirus, transcription is multiply initiated with specific 5' nucleotide sequences. The results indicate that, for all five viruses, the initiation of transcription involves similar sequences (e.g., pppApCpGp..., pppGpCp..., and possibly one or two other sequences), suggesting relatedness and some genome conservation among these viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362867"}
{"pmid": "4362868", "title": "Antigenic phenotypes and complementation groups of temperature-sensitive mutants of simian virus 40.", "content": "Antigenic phenotypes and complementation groups of temperature-sensitive mutants of simian virus 40. The antigenic phenotypes of several temperature-sensitive mutants of simian virus 40 were determined by an immunofluorescence microtechnique that allowed a very high degree of internal control for the conditions of virus infection and antigenic staining. The tumor (T), U, capsid protein (C), and virion (V) antigens were investigated. Productive infection in monkey cells and abortive infection in mouse cells were simultaneously monitored for antigen production at both permissive and restrictive temperatures. Complementation analyses of the mutants demonstrated two complementing groups (A and B) and one noncomplementing group ((*)). One of the complementing groups could be subdivided into two subgroups having very different antigenic phenotypes. The following phenotypes were observed at the restrictive temperature in monkey cells. (i) The noncomplementing group produced none of the antigens. (ii) Group A induced T antigen in moderately but consistently reduced numbers of cells. Other antigens were markedly reduced or absent. (iii) Some of the group B mutants produced T antigen but little or no U and V antigens. The C antigen appeared in the nucleolus and cytoplasm of this subgroup. (iv) In the other group B mutants, antigen synthesis was not altered. Similar phenotypes were observed in mouse cells, except that U, C, and V antigens could not be detected during either the mutant or wild-type virus infections at any temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362868"}
{"pmid": "4362869", "title": "Characterization of new regulatory mutants of bacteriophage T4.", "content": "Characterization of new regulatory mutants of bacteriophage T4. Plating techniques which eliminate T4 plaque formation on Escherichia coli by folate analogue inhibition of dihydrofolate (FH(2)) reductase (EC 1.5.1.3) allowed the isolation of folate analogue-resistant (far) mutants of T4. One class of far mutants overproduces the phage-induced FH(2) reductase. Deoxycytidylate deaminase (EC 3.5.4.12), thymidine kinase (EC 2.7.1.21), and deoxycytidine triphosphatase (EC 3.6.1.12) are also overproduced by 20 min after infection at 37 C. The overproduction of FH(2) reductase by these far mutants is not affected by the absence of DNA synthesis. Other types of mutations that affect the synthesis of early enzymes cause overproduction in the absence of DNA synthesis of some of the above enzymes but not of FH(2) reductase. Therefore, overproducing far mutants apparently have mutations in previously undescribed genes controlling the expression of the T4 genome. Three of four mutants under study map near gene 56, and one maps near gene 52. All of these mutants show delays in DNA synthesis, phage production, and lysis and appear to show decreased levels of RNA synthesis based on the cumulative incorporation of uridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362869"}
{"pmid": "4362871", "title": "Gene expression during the development of bacteriophage phi 29. 3. Analysis of viral-specific protein synthesis with suppressible mutants.", "content": "Gene expression during the development of bacteriophage phi 29. 3. Analysis of viral-specific protein synthesis with suppressible mutants. Fifty-four suppressible mutants of bacteriophage phi29 have been isolated with a variety of mutagens and assigned to eight complementation groups. Viral-specific protein synthesis in UV light-irradiated, nonsuppressing Bacillus subtilis 60084 was analyzed with exponential acrylamide gels. Four additional phi29 proteins which were undetected on ordinary acrylamide gels are reported in this paper. Five phage phi29 proteins have been unambiguously assigned to specific cistrons. Two cistrons had pleiotropic effects on viral protein synthesis. Mutants in cistrons I or II were unable to synthesize DNA in nonsuppressing bacteria. Mutants in cistron I were unable to attach viral chromosomes to the host cell membrane, and the protein responsible for this function has been identified. The other viral protein playing a role in phage phi29 DNA synthesis is also identified and assigned to cistron II. Mutants in cistron II can attach viral chromosomes to membrane, but cannot synthesize DNA in nonsuppressing bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362871"}
{"pmid": "4362870", "title": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. IX. Template topography in the early region of simian virus 40.", "content": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. IX. Template topography in the early region of simian virus 40. The DNAs of the five nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid viruses contain overlapping segments of the early region of wild-type SV40 DNA. The complementary DNA strands of these five viruses have been separated with synthetic polyribonucleotides in isopycnic cesium chloride gradients. The relative amounts of early and late SV40 template in the DNA of each virus were determined by RNA-DNA hybridization with late lytic SV40 RNA, which contains sequences complementary to both templates. From the distribution of early and late templates in the five overlapping SV40 segments, we conclude that either the entire early region of SV40 is symmetrically transcribed in vivo, or, more probably, that the early SV40 templates are not contiguous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362870"}
{"pmid": "4362860", "title": "Anthropology, nursing and mental health.", "content": "Anthropology, nursing and mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362860"}
{"pmid": "4362872", "title": "Immunochemical procedure for partial purification of newly synthesized proteins in polyoma virus-infected mouse cells.", "content": "Immunochemical procedure for partial purification of newly synthesized proteins in polyoma virus-infected mouse cells. A broad-spectrum antiserum has been obtained against nuclear proteins from normal mouse fibroblasts. Solid phase immunoadsorbants prepared from the serum specifically bind the corresponding antigens. The removal in this way of a significant fraction of host proteins leads to partial purification of viral and virus-induced polypeptides from polyoma virus-infected cell extracts. Four main peptides can be selected, with respective molecular weights of 90,000, 70,000, 46,000, and 41,000.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362872"}
{"pmid": "4362874", "title": "Spontaneous toxoplasmosis in macaques: a report of four cases.", "content": "Spontaneous toxoplasmosis in macaques: a report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362874"}
{"pmid": "4362873", "title": "Fragmentation of RNA in virus particles of rhinovirus type 14.", "content": "Fragmentation of RNA in virus particles of rhinovirus type 14. Purified particles of rhinovirus type 14 lose infectivity during incubation at 34.5 C as a result of fragmentation of RNA genomes within intact virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362873"}
{"pmid": "4362875", "title": "Feline infectious peritonitis in a closed breeding colony.", "content": "Feline infectious peritonitis in a closed breeding colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362875"}
{"pmid": "4362876", "title": "Silvered leaf-monkeys (Presbytis cristatus). I. Colony management, caging, diet, and biologic values.", "content": "Silvered leaf-monkeys (Presbytis cristatus). I. Colony management, caging, diet, and biologic values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362876"}
{"pmid": "4362877", "title": "Silvered leaf-monkeys (Presbytis cristatus). II. Gastrointestinal parasites and their treatment.", "content": "Silvered leaf-monkeys (Presbytis cristatus). II. Gastrointestinal parasites and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362877"}
{"pmid": "4362878", "title": "Colonization patterns of aerobic gram-negative bacteria in the cloaca of Rana pipiens.", "content": "Colonization patterns of aerobic gram-negative bacteria in the cloaca of Rana pipiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362878"}
{"pmid": "4362879", "title": "The effects of various levels of dietary fat and apple supplementation of growth of golden hamsters (Mesocricetus auratus).", "content": "The effects of various levels of dietary fat and apple supplementation of growth of golden hamsters (Mesocricetus auratus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362879"}
{"pmid": "4362880", "title": "Comparative erythrocyte metabolism: studies using guinea pig cells.", "content": "Comparative erythrocyte metabolism: studies using guinea pig cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362880"}
{"pmid": "4362881", "title": "Tuberculous spondylitis and Pott's paraplegia in a rhesus monkey (Macaca mulatta).", "content": "Tuberculous spondylitis and Pott's paraplegia in a rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362881"}
{"pmid": "4362882", "title": "A technic for thymectomy in the adult rat.", "content": "A technic for thymectomy in the adult rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362882"}
{"pmid": "4362883", "title": "A technic for neonatal thymectomy in marmoset monkeys.", "content": "A technic for neonatal thymectomy in marmoset monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362883"}
{"pmid": "4362884", "title": "Modification of the orbital sinus bleeding technic for rabbits.", "content": "Modification of the orbital sinus bleeding technic for rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362884"}
{"pmid": "4362885", "title": "Hexamitiasis in laboratory mice, hamsters, and rats.", "content": "Hexamitiasis in laboratory mice, hamsters, and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362885"}
{"pmid": "4362886", "title": "A simple procedure for long-term intravenous infusion in the rat.", "content": "A simple procedure for long-term intravenous infusion in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362886"}
{"pmid": "4362887", "title": "An exteriorized cranial vena caval catheter for serial blood sample collection from miniature swine.", "content": "An exteriorized cranial vena caval catheter for serial blood sample collection from miniature swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362887"}
{"pmid": "4362888", "title": "A simple hydraulic manostat for use with volume-controlled respirators.", "content": "A simple hydraulic manostat for use with volume-controlled respirators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362888"}
{"pmid": "4362889", "title": "A restraint device for electroejaculation of squirrel monkeys (Saimiri sciureus).", "content": "A restraint device for electroejaculation of squirrel monkeys (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362889"}
{"pmid": "4362890", "title": "Carotid-jugular arteriovenous fistulas for chronic hemodialysis in dogs.", "content": "Carotid-jugular arteriovenous fistulas for chronic hemodialysis in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362890"}
{"pmid": "4362891", "title": "Unilateral renal and urogenital tract aplasia in a guinea pig (Cavia porcellus).", "content": "Unilateral renal and urogenital tract aplasia in a guinea pig (Cavia porcellus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362891"}
{"pmid": "4362892", "title": "A new date mating system for mice in timer-activated breeding cages.", "content": "A new date mating system for mice in timer-activated breeding cages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362892"}
{"pmid": "4362893", "title": "The opposum (Didelphis virginiana Kerr) as a biomedical model. I. Research perspective, husbandry, and laboratory technics.", "content": "The opposum (Didelphis virginiana Kerr) as a biomedical model. I. Research perspective, husbandry, and laboratory technics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362893"}
{"pmid": "4362894", "title": "The opossum (Didelphis virginiana Kerr) as a biomedical model. II. Breeding the opossum in captivity: facility design.", "content": "The opossum (Didelphis virginiana Kerr) as a biomedical model. II. Breeding the opossum in captivity: facility design.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362894"}
{"pmid": "4362895", "title": "The opossum (Didelphis virginiana Kerr) as a biomedical model. 3. Breeding the opossum in captivity: methods.", "content": "The opossum (Didelphis virginiana Kerr) as a biomedical model. 3. Breeding the opossum in captivity: methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362895"}
{"pmid": "4362896", "title": "Letter: Effect of prolonged treatment of high doses of chorionic gonadotropin on immature male rats.", "content": "Letter: Effect of prolonged treatment of high doses of chorionic gonadotropin on immature male rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362896"}
{"pmid": "4362897", "title": "Letter: Identification methods for rodents.", "content": "Letter: Identification methods for rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362897"}
{"pmid": "4362899", "title": "A study of nutritional status of preschool children in the United States, 1968-1970.", "content": "A study of nutritional status of preschool children in the United States, 1968-1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362899"}
{"pmid": "4362900", "title": "Neonatal screening for hyperlipidemia.", "content": "Neonatal screening for hyperlipidemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362900"}
{"pmid": "4362901", "title": "Cholesterol at birth and age 1: comparison of normal and hypercholesterolemic neonates.", "content": "Cholesterol at birth and age 1: comparison of normal and hypercholesterolemic neonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362901"}
{"pmid": "4362907", "title": "Editorial: Current status of our knowledge about cyclic AMP.", "content": "Editorial: Current status of our knowledge about cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362907"}
{"pmid": "4362908", "title": "Stimulation at 50 pulses per second in the normal person: its implication in the differential diagnosis from myasthenia gravis and myasthenic syndrome.", "content": "Stimulation at 50 pulses per second in the normal person: its implication in the differential diagnosis from myasthenia gravis and myasthenic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362908"}
{"pmid": "4362909", "title": "Bilateral adrenalectomy in selected patients with carcinoma of the breast.", "content": "Bilateral adrenalectomy in selected patients with carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362909"}
{"pmid": "4362910", "title": "Synovial sarcoma in children.", "content": "Synovial sarcoma in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362910"}
{"pmid": "4362912", "title": "Neutralization of the hemodynamic effects of endotoxin by polymyxin B.", "content": "Neutralization of the hemodynamic effects of endotoxin by polymyxin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362912"}
{"pmid": "4362911", "title": "The clinical application of a specific radioimmunoassay for human chorionic gondotropin in trophoblastic and nontrophoblastic tumors.", "content": "The clinical application of a specific radioimmunoassay for human chorionic gondotropin in trophoblastic and nontrophoblastic tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362911"}
{"pmid": "4362913", "title": "Ultrastructural changes in the liver of equine fetuses aborted during rhinopneumonitis.", "content": "Ultrastructural changes in the liver of equine fetuses aborted during rhinopneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362913"}
{"pmid": "4362914", "title": "Malignant fibrous histiocytoma of the vagina.", "content": "Malignant fibrous histiocytoma of the vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362914"}
{"pmid": "4362915", "title": "Investigation of the release reaction in platelets exposed to phorbol myristate acetate.", "content": "Investigation of the release reaction in platelets exposed to phorbol myristate acetate. Phorbol myristate acetate (PMA), the active principle of croton oil, is a potent platelet aggregating agent. Previous cytochemical and electron microscopic studies demonstrated that PMA caused selective labilization of platelet storage granules resulting in their conversion to distended vacuoles. Communication was established between the enlarged, almost empty vacuoles and the surrounding plasma through channels of the open canalicular system. The present study has explored the possibility that the effect of PMA on platelet storage organelles stimulates a process of secretion. Analysis of the release reaction in platelets after exposure to PMA revealed that significant amounts of serotonin and adenine nucleotides were secreted without loss of lactic dehydrogenase. Release took place well before the onset of irreversible aggregation. Inhibitors of platelet secretion or ADP induced aggregation could modify or prevent the irreversible clumping stimulated by small concentrations of PMA. Although the secretion induced by PMA differed from the release caused by other agents, the findings of the present study indicate that PMA is capable of triggering the platelet release reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362915"}
{"pmid": "4362916", "title": "Experimental adenovirus infection of the mouse adrenal gland. I. Light microscopic observations.", "content": "Experimental adenovirus infection of the mouse adrenal gland. I. Light microscopic observations. A murine type of adenovirus has been found to have a highly selective affinity for the adrenal of its natural host. In view of the adrenal pathology in Addison's disease, which consists of cortical atrophy and focal lymphocytic infiltration, the possibility of a viral causation is an attractive hypothesis. The striking adrenotropism of this agent offers, theoretically, a potential experimental animal model for investigation of this possibility. Most of our information about the acute biologic action of adenoviruses has been gained from study of virus-infected tissue culture cells. The sharply focused and severe attack of the murine agent upon a prime target organ facilitates correlative in vivo studies of the cytopathology of adenovirus infection at levels of light and electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362916"}
{"pmid": "4362918", "title": "Animal model of human disease. Malignant lymphoma.", "content": "Animal model of human disease. Malignant lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362918"}
{"pmid": "4362917", "title": "Experimental adenovirus infection of the mouse adrenal gland. II. Electron microscopic observations.", "content": "Experimental adenovirus infection of the mouse adrenal gland. II. Electron microscopic observations. A strain of mouse adenovirus, found to have a striking tropism for the weanling mouse adrenal gland, enabled electron microscopic examination of adrenals in various stages of infection. Nucleolar hypertrophy and the successive formation of three types of inclusion bodies in association with nucleoli preceded virion production. Angular crystals of virions formed in the affected nuclei. Virus was released by lysis of nuclear membranes; rapid degeneration of cytoplasmic organelles followed. Rupture of external cell membranes released virus into the extracellular spaces where virions crossed vascular basement membranes to enter endothelial cells. Virions were also phagocytized by inflammatory cells which reentered vascular sinusoids, and by adrenal parenchymal cells. Disruption of virus-laden phagocytic vacuoles in parenchymal cells released virions into the cytoplasm. Typical viral inclusion bodies also formed in vascular endothelial cells and in inflammatory cells, but virion replication was not detected. The possibility that virus directly entered parenchymal cells through the external cell membrane without phagocytosis is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362917"}
{"pmid": "4362919", "title": "Spontaneous regression of cancer: the metabolic triumph of the host?", "content": "Spontaneous regression of cancer: the metabolic triumph of the host?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362919"}
{"pmid": "4362920", "title": "Hypoglycemia associated with neoplasia.", "content": "Hypoglycemia associated with neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362920"}
{"pmid": "4362921", "title": "Paraneoplastic syndromes. Hyperadrenocorticism and ACTH-releasing factor.", "content": "Paraneoplastic syndromes. Hyperadrenocorticism and ACTH-releasing factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362921"}
{"pmid": "4362922", "title": "Neurogenic paraneoplastic syndromes. The brain's uneasy peace with tumors.", "content": "Neurogenic paraneoplastic syndromes. The brain's uneasy peace with tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362922"}
{"pmid": "4362923", "title": "Paraneoplastic syndromes of nerve muscle, and neuromuscular junction.", "content": "Paraneoplastic syndromes of nerve muscle, and neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362923"}
{"pmid": "4362924", "title": "The paraneoplastic syndromes associated with carcinoma of the thyroid gland.", "content": "The paraneoplastic syndromes associated with carcinoma of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362924"}
{"pmid": "4362926", "title": "Epigenetic mechanisms and paraneoplastic phenomena.", "content": "Epigenetic mechanisms and paraneoplastic phenomena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362926"}
{"pmid": "4362925", "title": "Why corticoids are effective against a wide variety of cancers.", "content": "Why corticoids are effective against a wide variety of cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362925"}
{"pmid": "4362927", "title": "The processing of visual information in a simple retina.", "content": "The processing of visual information in a simple retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362927"}
{"pmid": "4362928", "title": "Two-hour embedding procedure for intracellular detection of viruses by electron microscopy.", "content": "Two-hour embedding procedure for intracellular detection of viruses by electron microscopy. An embedding method requiring only 2 h to complete and giving excellent ultrastructural preservation has been used for the rapid detection of viruses in tissue cultures. The method has also been applied successfully to mammalian tissue. It provides a rapid technique for identifying viruses isolated in tissue cultures, for screening cultures for adventitious agents, and for examining tissue biopsies for viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362928"}
{"pmid": "4362929", "title": "Utilization of a further miniaturized serological microtechnique.", "content": "Utilization of a further miniaturized serological microtechnique. A new 0.01-ml serological microtechnique system produced accurate and reproducible complement-fixation and indirect hemagglutination tests. This equipment involves the use of smaller amounts of antigens and sera, and thus increases the value of the method when employed with expensive reagents or limited qualities of sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362929"}
{"pmid": "4362930", "title": "Exogenous and endogenous provocation of psoriasis. A contribution to the Koebner phenomenon.", "content": "Exogenous and endogenous provocation of psoriasis. A contribution to the Koebner phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362930"}
{"pmid": "4362931", "title": "Experimental herpesvirus infection of baboons (Papio cynocephalus) and African green monkeys (Cercopithecus aethiops) and recovery of virus by tissue explants.", "content": "Experimental herpesvirus infection of baboons (Papio cynocephalus) and African green monkeys (Cercopithecus aethiops) and recovery of virus by tissue explants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362931"}
{"pmid": "4362932", "title": "Intracellular neutralization of poliovirus by type-specific antiserum.", "content": "Intracellular neutralization of poliovirus by type-specific antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362932"}
{"pmid": "4362933", "title": "Non-infectious intracisternal A-type particles in a sarcoma-positive, leukemia-negative mouse cell line transformed by murine sarcoma virus (MSV).", "content": "Non-infectious intracisternal A-type particles in a sarcoma-positive, leukemia-negative mouse cell line transformed by murine sarcoma virus (MSV).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362933"}
{"pmid": "4362934", "title": "Studies on temperature-sensitive events in synthesis of poliovirus ts mutants.", "content": "Studies on temperature-sensitive events in synthesis of poliovirus ts mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362934"}
{"pmid": "4362936", "title": "Conformations of cyclic 3',5'-nucleotides. Effect of the base on the synanti conformer distribution.", "content": "Conformations of cyclic 3',5'-nucleotides. Effect of the base on the synanti conformer distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362936"}
{"pmid": "4362935", "title": "Feline \"foamy\" viruses: incidence in Australia.", "content": "Feline \"foamy\" viruses: incidence in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362935"}
{"pmid": "4362937", "title": "Nuclear columns: labeling and release of virus specific RNA by nuclei of DNA-virus (SV 40) infected cells.", "content": "Nuclear columns: labeling and release of virus specific RNA by nuclei of DNA-virus (SV 40) infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362937"}
{"pmid": "4362940", "title": "Interaction of diethylpyrocarbonate with poliovirus double-stranded RNA.", "content": "Interaction of diethylpyrocarbonate with poliovirus double-stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362940"}
{"pmid": "4362938", "title": "Rapid, periodate-induced stimulation of permeability and macromolecular synthesis in chicken erythrocytes.", "content": "Rapid, periodate-induced stimulation of permeability and macromolecular synthesis in chicken erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362938"}
{"pmid": "4362939", "title": "A study of the interaction of human spermatozoa membrane with ATP and cyclic-AMP.", "content": "A study of the interaction of human spermatozoa membrane with ATP and cyclic-AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362939"}
{"pmid": "4362941", "title": "The oxidation state of newly synthesized hemoglobin.", "content": "The oxidation state of newly synthesized hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362941"}
{"pmid": "4362943", "title": "Metabolic regulation of steroidogenesis in adrenocortical carcinoma cells of rat. Effect of adrenocorticotropin and adenosine cyclic 3',5'-monophosphate on the incorporation of (20S)-20-hydroxy(7 alpha-3H)cholesterol into deoxycorticosterone and corticosterone.", "content": "Metabolic regulation of steroidogenesis in adrenocortical carcinoma cells of rat. Effect of adrenocorticotropin and adenosine cyclic 3',5'-monophosphate on the incorporation of (20S)-20-hydroxy(7 alpha-3H)cholesterol into deoxycorticosterone and corticosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362943"}
{"pmid": "4362942", "title": "Synthesis of DNA complementary to AMV RNA using E. coli polymerase I.", "content": "Synthesis of DNA complementary to AMV RNA using E. coli polymerase I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362942"}
{"pmid": "4362946", "title": "Inhibition of choline kinase by selectively cytotoxic purinyl-6-histamine.", "content": "Inhibition of choline kinase by selectively cytotoxic purinyl-6-histamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362946"}
{"pmid": "4362945", "title": "Isolation of a divalent cation ionophore from beef heart mitochondria.", "content": "Isolation of a divalent cation ionophore from beef heart mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362945"}
{"pmid": "4362944", "title": "Synthesis of DNA, RNA protein and glycoprotein in mitochondria of cells transformed with Rous sarcoma viruses.", "content": "Synthesis of DNA, RNA protein and glycoprotein in mitochondria of cells transformed with Rous sarcoma viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362944"}
{"pmid": "4362947", "title": "Spin label translational diffusion in solid tristearin.", "content": "Spin label translational diffusion in solid tristearin. Translational diffusion of the intermediate chain length spin label 7N14 has been detected and studied in a lipid environment which is in the bulk solid state. Under favorable circumstances this can occur at temperatures as much as 50 degrees C below the optical melting point. Translational diffusion allows 7N14 molecules to coalesce into impurity pools of high spin label concentration. Two other spin labels, 2N3 and 14N27, do not show a tendency to form such impurity pools. While 2N3 undergoes rapid tumbling at temperatures far below the melting point of the tristearin matrix, the molecules remain in an isolated state with no evidence of spin exchange. 14N27 is restricted in rotational motion in the solid matrix and also does not form impurity pools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362947"}
{"pmid": "4362948", "title": "Calcium dependence of the inhibitory effect of angiotensin on renin secretion in the isolated perfused kidney of the rat.", "content": "Calcium dependence of the inhibitory effect of angiotensin on renin secretion in the isolated perfused kidney of the rat. 1 The effect of calcium on the inhibition of renin secretion by biologically active angiotensin was investigated in the isolated rat kidney perfused with Krebs-Ringer saline.2 In the presence of calcium (3.7 mM), asp(NH(2))'-angiotensin II suppressed both basal and isoprenaline-stimulated renin secretion. Renal perfusion pressure, which was increased by the infusion of angiotensin, returned to control levels when isoprenaline was added.3 When the calcium concentration was reduced to 0.32 mM, the vasoconstriction produced by angiotensin was abolished although the inhibitory effect on renin secretion was still evident.4 In the absence of calcium, angiotensin no longer suppressed basal renin secretion and a prompt increase in renin secretion occurred when isoprenaline was added.5 The higher basal renin levels which were observed in calcium-free perfusions, suggest the existence of an intrarenal calcium-dependent mechanism that regulates basal renin secretion.6 These observations indicate that the inhibitory effect of biologically active angiotensin, on basal and isoprenaline-stimulated renin secretion, is functionally related to the contractor response by its dependence on calcium. The recognition that the renin-producing cells are modified smooth muscle cells supports this association", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362948"}
{"pmid": "4362951", "title": "Studies on the tachyphylaxis to nicotinic stimulant drugs in the perfused hypogastric ganglion of the guinea-pig.", "content": "Studies on the tachyphylaxis to nicotinic stimulant drugs in the perfused hypogastric ganglion of the guinea-pig. 1 The guinea-pig hypogastric ganglion, perfused through its vasculature with physiological saline solutions, will respond repeatedly to nicotinic stimulant drugs injected at 4 min intervals into the perfusion stream. Stimulation is indicated by contraction of the vas deferens. After a varying number of doses of nicotinic stimulants, complete tachyphylaxis usually develops, and normally this persists for at least 1 hour. During this time, however, electrical stimulation of the hypogastric nerve is still fully effective.2 Tachyphylaxis may be reversed for varying periods of time by all of the following procedures: (a) tetanic stimulation of the hypogastric nerve; (b) injection of large doses of histamine, methacholine, or potassium chloride; (c) perfusion with saline containing ouabain 0.1 mug/ml or 80-100 mM lithium chloride, or, to a lesser extent, with potassium-free saline.3 Tachyphylaxis is always re-established with further doses of nicotinic stimulants, except during perfusion with lithium solutions.4 Atropine hastens the onset of tachyphylaxis, but does not prevent its reversal by hypogastric nerve stimulation or by histamine or potassium. However, it does prevent the reversal by methacholine and by lithium.5 Tachyphylaxis occurs in decentralized ganglia, and can be reversed by histamine, methacholine, and by tetanic stimulation of the hypogastric ganglion. Hence tachyphylaxis and its reversal cannot be due to an effect on presynaptic fibres.6 Potassium chloride stimulates the ganglion both before and after tachyphylaxis has developed to nicotinic drugs, and hence this is unlikely to be due to a depolarization block.7 It is concluded that tachyphylaxis could be due to a prolonged ganglionic hyperpolarization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362951"}
{"pmid": "4362950", "title": "Morphine and neurotransmitter substances: Microiontophoretic study in the rat brain stem.", "content": "Morphine and neurotransmitter substances: Microiontophoretic study in the rat brain stem. 1 The effects of microiontophoretically applied morphine and its interactions with the effects of microiontophoretic applications of either acetylcholine, (-)-noradrenaline or 5-hydroxytryptamine have been studied on single neurones in the brain stem of rats anaesthetized with urethane.2 Morphine excited or inhibited most neurones tested and the effects, especially excitation, were often extremely powerful. However, the time course of the excitatory and inhibitory effects were somewhat different.3 Desensitization to the excitation produced by morphine was seen after repeated or prolonged applications and it is suggested that this phenomenon may be related to the tolerance which develops after chronic administration of morphine. No desensitization was observed to inhibition of neuronal activity by morphine.4 Morphine usually reduced the excitation of neurones by acetylcholine, noradrenaline or 5-hydroxytryptamine but sometimes potentiated the effect, although not always on the same neurones. Inhibition of neuronal activity by these compounds was never modified by morphine and neither were the effects of glutamate or D,L-homocysteic acid when used as control agonists.5 The in vitro release of morphine from six micropipettes was determined and the transport number was calculated to be 0.051 (s.d. 0.021).6 The implications of these observations in explaining the pharmacological actions of morphine are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362950"}
{"pmid": "4362953", "title": "Benign clear cell tumor of the lung. An ultrastructural study.", "content": "Benign clear cell tumor of the lung. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362953"}
{"pmid": "4362952", "title": "Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx: A clinicopathologic study. I. General features and vascular tumors.", "content": "Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx: A clinicopathologic study. I. General features and vascular tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362952"}
{"pmid": "4362949", "title": "Studies on the coronary dilator actions of some adenosine analogues.", "content": "Studies on the coronary dilator actions of some adenosine analogues. 1 The cardiovascular actions of 23 adenosine analogues have been examined in anaesthetized open thorax dogs; the analogues were substituted in the 2-position of the purine ring, or in the exocyclic amino group, or were modified in the imidazole or sugar rings.2 The effects of these compounds on coronary blood flow, peripheral blood pressure, and heart rate were compared with those of adenosine.3 9-beta-D-Arabinofuranosyladenine had no cardiovascular action; the other analogues on intra-atrial administration caused an immediate increase in coronary blood flow, the magnitude and duration of which varied with the structures of the analogues.4 2-Fluoro-, 2-bromo-, 2-isobutylthio-, 2-ethylamino-, and 5'-deoxy-5'-chloro- adenosines had coronary dilator potencies equal to or greater than that of adenosine. No relationship was found between the dilator potency of the adenosine analogues and their duration of coronary dilator action.5 The coronary dilator action of adenosine was potentiated by inosine, 9-beta-D-arabinofurano-syladenine, tubercidin, N(6)-methyladenosine and 2-trifluoromethyl-N(6)-methyladenosine.6 There was no correlation between the substrate specificities of the shorter-acting analogues for adenosine deaminase or adenosine kinase and their duration of coronary dilator action.7 It is proposed that in the anaesthetized dog, uptake into tissues is a more important mode of removal of adenosine and adenosine analogues from the vascular system than inactivation by adenosine deaminase, that the duration of coronary dilator action of the analogues is related primarily to their specificity for the carrier which mediates adenosine uptake, and that the adenosine carrier is not associated with kinase action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362949"}
{"pmid": "4362955", "title": "Sacrococcygeal teratoma with nephroblastoma (Wilm's tumor): a variant of extragonadal teratoma in childhood. A histologic and ultrastructural study.", "content": "Sacrococcygeal teratoma with nephroblastoma (Wilm's tumor): a variant of extragonadal teratoma in childhood. A histologic and ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362955"}
{"pmid": "4362954", "title": "Carcinoid tumor of the pancreas. Ultrastructural observations of a lymph node metastasis and comparison with bronchial carcinoid.", "content": "Carcinoid tumor of the pancreas. Ultrastructural observations of a lymph node metastasis and comparison with bronchial carcinoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362954"}
{"pmid": "4362959", "title": "Familial occurrences of a variety of premalignant diseases and uncommon malignant neoplasms.", "content": "Familial occurrences of a variety of premalignant diseases and uncommon malignant neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362959"}
{"pmid": "4362957", "title": "Childhood non-Hodgkin's lymphoma--a study of 17 cases in Israel.", "content": "Childhood non-Hodgkin's lymphoma--a study of 17 cases in Israel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362957"}
{"pmid": "4362956", "title": "Malignant and benign human mammary disease: estrogen binding in relation to clinical data.", "content": "Malignant and benign human mammary disease: estrogen binding in relation to clinical data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362956"}
{"pmid": "4362960", "title": "Glutamine-dependent carbamyl phosphate synthetase during fetal and neonatal life in the rat.", "content": "Glutamine-dependent carbamyl phosphate synthetase during fetal and neonatal life in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362960"}
{"pmid": "4362958", "title": "Bilateral nephroblastomatosis and Klippel Trenaunay syndrome.", "content": "Bilateral nephroblastomatosis and Klippel Trenaunay syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362958"}
{"pmid": "4362961", "title": "Changes in the activity of selected enzymes during starvation of Physarum polycephalum.", "content": "Changes in the activity of selected enzymes during starvation of Physarum polycephalum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362961"}
{"pmid": "4362963", "title": "Temporal effects of LH, hCG, FSH and dibutyryl cyclic 3',5'-AMP upon luteinization of rhesus monkey granulosa cells in culture.", "content": "Temporal effects of LH, hCG, FSH and dibutyryl cyclic 3',5'-AMP upon luteinization of rhesus monkey granulosa cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362963"}
{"pmid": "4362962", "title": "Studies on the developmental pattern of the enzymes converting glucose 6-phosphate to myo-inositol in the rat.", "content": "Studies on the developmental pattern of the enzymes converting glucose 6-phosphate to myo-inositol in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362962"}
{"pmid": "4362964", "title": "TSH stimulation of iodothyronine formation in prelabeled thyroglobulin of hypophysectomized rats.", "content": "TSH stimulation of iodothyronine formation in prelabeled thyroglobulin of hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362964"}
{"pmid": "4362965", "title": "The preparation of biologically active 125I-labeled adrenocorticotrophic hormone by a simple enzymic radioiodination procedure utilizing lactoperoxidase.", "content": "The preparation of biologically active 125I-labeled adrenocorticotrophic hormone by a simple enzymic radioiodination procedure utilizing lactoperoxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362965"}
{"pmid": "4362966", "title": "Effects of biogenic amines on the formation of adenosine 3',5'-monophosphate in porcine cerebral cortex, hypothalamus and anterior pituitary slices.", "content": "Effects of biogenic amines on the formation of adenosine 3',5'-monophosphate in porcine cerebral cortex, hypothalamus and anterior pituitary slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362966"}
{"pmid": "4362967", "title": "1Alpha-hydroxyvitamin D3: a synthetic sterol which is highly active in preventing rickets in the chick.", "content": "1Alpha-hydroxyvitamin D3: a synthetic sterol which is highly active in preventing rickets in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362967"}
{"pmid": "4362970", "title": "Autoradiographic localization of 3H-estradiol or its metabolites in the central nervous system of the developing rat.", "content": "Autoradiographic localization of 3H-estradiol or its metabolites in the central nervous system of the developing rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362970"}
{"pmid": "4362968", "title": "Effects of hypophysectomy and ACTH on adrenocortical function in the rat.", "content": "Effects of hypophysectomy and ACTH on adrenocortical function in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362968"}
{"pmid": "4362969", "title": "Responses of adipose tissue to sequential lipolytic stimuli.", "content": "Responses of adipose tissue to sequential lipolytic stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362969"}
{"pmid": "4362971", "title": "Stimulation of ketogenesis by dibutyryl cyclic AMP in isolated rat hepatocytes.", "content": "Stimulation of ketogenesis by dibutyryl cyclic AMP in isolated rat hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362971"}
{"pmid": "4362973", "title": "Apparent positive cooperative effects in cyclic AMP and corticosterone production by isolated adrenal cells in response to ACTH analogues.", "content": "Apparent positive cooperative effects in cyclic AMP and corticosterone production by isolated adrenal cells in response to ACTH analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362973"}
{"pmid": "4362972", "title": "Effects of prostaglandins on hepatic adenylate cyclase activity and cyclic adenosine 3',5',-monophosphate content.", "content": "Effects of prostaglandins on hepatic adenylate cyclase activity and cyclic adenosine 3',5',-monophosphate content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362972"}
{"pmid": "4362974", "title": "Angiographic analysis of factors influencing coronary artery bypass patency.", "content": "Angiographic analysis of factors influencing coronary artery bypass patency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362974"}
{"pmid": "4362993", "title": "Isolation of cold-sensitive mutants of poliovirus.", "content": "Isolation of cold-sensitive mutants of poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362993"}
{"pmid": "4362994", "title": "Complementation and phenotypic stabilization of vesicular stomatitis virus temperature-sensitive and thermolabile mutants by avian myeloblastosis virus.", "content": "Complementation and phenotypic stabilization of vesicular stomatitis virus temperature-sensitive and thermolabile mutants by avian myeloblastosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362994"}
{"pmid": "4362992", "title": "Immunologic and genetic relationship between herpes simplex virus and bovine herpes mammillitis virus.", "content": "Immunologic and genetic relationship between herpes simplex virus and bovine herpes mammillitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362992"}
{"pmid": "4362995", "title": "Detection of virus-induced membrane and cytoplasmic antigens: comparison of the 125I-labeled antiviral antibody binding technique with immunofluorescence.", "content": "Detection of virus-induced membrane and cytoplasmic antigens: comparison of the 125I-labeled antiviral antibody binding technique with immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362995"}
{"pmid": "4362997", "title": "Relationship between cytomegalovirus and hepatic function abnormalities in the period after renal transplant.", "content": "Relationship between cytomegalovirus and hepatic function abnormalities in the period after renal transplant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362997"}
{"pmid": "4362996", "title": "The effect of lorazepam on anxious insomniacs' sleep as recorded in the home environment.", "content": "The effect of lorazepam on anxious insomniacs' sleep as recorded in the home environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362996"}
{"pmid": "4362998", "title": "Cyclacillin: a clinical and in vitro profile.", "content": "Cyclacillin: a clinical and in vitro profile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362998"}
{"pmid": "4362999", "title": "Binding of antibiotics to a soluble protein from rat liver.", "content": "Binding of antibiotics to a soluble protein from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4362999"}
{"pmid": "4363000", "title": "Neurologic complications associated with acute hemorrhagic conjunctivitis virus infection and its serologic confirmation.", "content": "Neurologic complications associated with acute hemorrhagic conjunctivitis virus infection and its serologic confirmation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363000"}
{"pmid": "4363002", "title": "Effect of various methods of epidermal-dermal separation on the distribution of 14C-acetate-labeled polyunsaturated fatty acids in skin compartments.", "content": "Effect of various methods of epidermal-dermal separation on the distribution of 14C-acetate-labeled polyunsaturated fatty acids in skin compartments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363002"}
{"pmid": "4363001", "title": "Cyclic 3',5'-nucleotide phosphodiesterase. I. Histochemical localization in rat skin.", "content": "Cyclic 3',5'-nucleotide phosphodiesterase. I. Histochemical localization in rat skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363001"}
{"pmid": "4363007", "title": "A spin label study of human erythrocyte ghost membranes damaged by methyl phenyldiazenecarboxylate (azoester).", "content": "A spin label study of human erythrocyte ghost membranes damaged by methyl phenyldiazenecarboxylate (azoester).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363007"}
{"pmid": "4363006", "title": "The effect of various secretagogues on accumulation of cyclic AMP and secretion of alpha-amylase from rat exocrine pancreas.", "content": "The effect of various secretagogues on accumulation of cyclic AMP and secretion of alpha-amylase from rat exocrine pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363006"}
{"pmid": "4363008", "title": "The influence of low and high doses of theophylline on spontaneous motility and cyclic 3',5' AMP content in isolated rat uterus.", "content": "The influence of low and high doses of theophylline on spontaneous motility and cyclic 3',5' AMP content in isolated rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363008"}
{"pmid": "4363009", "title": "The role of calcium in the central effects of biogenic amines.", "content": "The role of calcium in the central effects of biogenic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363009"}
{"pmid": "4363011", "title": "Specific angiotensin II receptors in organ-cultured canine supra-optic nucleus cells.", "content": "Specific angiotensin II receptors in organ-cultured canine supra-optic nucleus cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363011"}
{"pmid": "4363013", "title": "Effect of angiotensin and norepinephrine on capillary pressure and filtration coefficient in isolated dog hindlimb.", "content": "Effect of angiotensin and norepinephrine on capillary pressure and filtration coefficient in isolated dog hindlimb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363013"}
{"pmid": "4363010", "title": "A new class of angiotensin inhibitors: N-methylphenylalanine analogs.", "content": "A new class of angiotensin inhibitors: N-methylphenylalanine analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363010"}
{"pmid": "4363012", "title": "Magnesium and contraction of arterial smooth muscle.", "content": "Magnesium and contraction of arterial smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363012"}
{"pmid": "4363014", "title": "Inhibition of adenosine cyclic 3', 5'-monophosphate accumulation in fat cells by adenosine, N6-(phenylisopropyl) adenosine, and related compounds.", "content": "Inhibition of adenosine cyclic 3', 5'-monophosphate accumulation in fat cells by adenosine, N6-(phenylisopropyl) adenosine, and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363014"}
{"pmid": "4363016", "title": "Effect of nerve degeneration by 6-hydroxydopamine on catecholamine-stimulated adenosine 3',5'-monophosphate formation in rat cerebral cortex.", "content": "Effect of nerve degeneration by 6-hydroxydopamine on catecholamine-stimulated adenosine 3',5'-monophosphate formation in rat cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363016"}
{"pmid": "4363015", "title": "Superinduction of serotonin N-acetyltransferase and supersensitivity of adenyl cyclase to catecholamines in denervated pineal gland.", "content": "Superinduction of serotonin N-acetyltransferase and supersensitivity of adenyl cyclase to catecholamines in denervated pineal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363015"}
{"pmid": "4363018", "title": "Induction of aryl hydrocarbon hydroxylase in mouse 3T3 cells: relationship to the state of cell proliferation and guanosine cyclic 3',5'-monophosphate.", "content": "Induction of aryl hydrocarbon hydroxylase in mouse 3T3 cells: relationship to the state of cell proliferation and guanosine cyclic 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363018"}
{"pmid": "4363017", "title": "Effects of the carcinogen N-acetoxy-2-fluorenylacetamide on the template properties of deoxyribonucleic acid.", "content": "Effects of the carcinogen N-acetoxy-2-fluorenylacetamide on the template properties of deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363017"}
{"pmid": "4363019", "title": "Changes in a surface-labelled galactoprotein and in glycolipid concentrations in cells transformed by a temperature-sensitive polyoma virus mutant.", "content": "Changes in a surface-labelled galactoprotein and in glycolipid concentrations in cells transformed by a temperature-sensitive polyoma virus mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363019"}
{"pmid": "4363020", "title": "Androgen receptors in a Syrian hamster ductus deferens tumour cell line.", "content": "Androgen receptors in a Syrian hamster ductus deferens tumour cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363020"}
{"pmid": "4363021", "title": "Serotonin and pituitary-adrenal function.", "content": "Serotonin and pituitary-adrenal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363021"}
{"pmid": "4363022", "title": "The structural and functional organization of the thyroid gland and special features of the tumours of this organ.", "content": "The structural and functional organization of the thyroid gland and special features of the tumours of this organ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363022"}
{"pmid": "4363026", "title": "Letter: Effect of exogenous oestrogens on minor psychiatric symptoms in postmenopausal women.", "content": "Letter: Effect of exogenous oestrogens on minor psychiatric symptoms in postmenopausal women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363026"}
{"pmid": "4363027", "title": "Percutaneous transhepatic cholangiography.", "content": "Percutaneous transhepatic cholangiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363027"}
{"pmid": "4363028", "title": "Enlargement of cavernous haemangioma associated with exogenous administration of oestrogens.", "content": "Enlargement of cavernous haemangioma associated with exogenous administration of oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363028"}
{"pmid": "4363034", "title": "Morphological and histochemical study on the major salivary glands of mice injected with dactinomycin.", "content": "Morphological and histochemical study on the major salivary glands of mice injected with dactinomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363034"}
{"pmid": "4363035", "title": "A simple apparatus and procedure for digestion of biologic materials in determinations of nonvolatile elements.", "content": "A simple apparatus and procedure for digestion of biologic materials in determinations of nonvolatile elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363035"}
{"pmid": "4363036", "title": "Pre-Descemet's membrane corneal dystrophy.", "content": "Pre-Descemet's membrane corneal dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363036"}
{"pmid": "4363037", "title": "Sporotrichosis of the orbital margin.", "content": "Sporotrichosis of the orbital margin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363037"}
{"pmid": "4363038", "title": "Protective immunity to amebic infection demonstrated in guinea pigs.", "content": "Protective immunity to amebic infection demonstrated in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363038"}
{"pmid": "4363040", "title": "Immunological reactions in kuru. Attempts to demonstrate serological relationships between karu and other known infectious agents.", "content": "Immunological reactions in kuru. Attempts to demonstrate serological relationships between karu and other known infectious agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363040"}
{"pmid": "4363039", "title": "Schistosomiasis and other human parasitoses of Lake Lindu in central Sulawesi (Celebes), Indonesia.", "content": "Schistosomiasis and other human parasitoses of Lake Lindu in central Sulawesi (Celebes), Indonesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363039"}
{"pmid": "4363043", "title": "Genetic control of resistance to mouse cytomegalovirus infection.", "content": "Genetic control of resistance to mouse cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363043"}
{"pmid": "4363041", "title": "The use of excisional therapy in the management of snakebite.", "content": "The use of excisional therapy in the management of snakebite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363041"}
{"pmid": "4363044", "title": "Comparison of the neuraminidases of three avian paramyxoviruses.", "content": "Comparison of the neuraminidases of three avian paramyxoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363044"}
{"pmid": "4363042", "title": "Dual primary bronchogenic carcinoma.", "content": "Dual primary bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363042"}
{"pmid": "4363045", "title": "Heterogeneity of rabbit serum interferon induced by poly I:C.", "content": "Heterogeneity of rabbit serum interferon induced by poly I:C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363045"}
{"pmid": "4363046", "title": "Activation of herpes specific antigens and infectious virus in a hamster cell line transformed by HSV-2.", "content": "Activation of herpes specific antigens and infectious virus in a hamster cell line transformed by HSV-2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363046"}
{"pmid": "4363048", "title": "Distribution of bound ADP-ribose derivatives in nuclear protein of rat liver nuclei.", "content": "Distribution of bound ADP-ribose derivatives in nuclear protein of rat liver nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363048"}
{"pmid": "4363050", "title": "Neurospora crassa and Humicola lanuginosa cytochromes c: more homology in the heme region.", "content": "Neurospora crassa and Humicola lanuginosa cytochromes c: more homology in the heme region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363050"}
{"pmid": "4363049", "title": "The isolation and the structure of new glycopeptide from blood group substances.", "content": "The isolation and the structure of new glycopeptide from blood group substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363049"}
{"pmid": "4363051", "title": "Isolation of plasma membranes from bovine corpus luteum possessing adenylate cyclase, 125I-hCG binding and Na-K-ATPase activities.", "content": "Isolation of plasma membranes from bovine corpus luteum possessing adenylate cyclase, 125I-hCG binding and Na-K-ATPase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363051"}
{"pmid": "4363052", "title": "The activation of motility in quiescent hamster sperm from the epididymis by calcium and cyclic nucleotides.", "content": "The activation of motility in quiescent hamster sperm from the epididymis by calcium and cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363052"}
{"pmid": "4363053", "title": "Biosynthesis of a P1-2-acetamido-2-deoxy-D-glucosyl P2-polyisoprenyl pyrophosphate by calf pancreas microsomes.", "content": "Biosynthesis of a P1-2-acetamido-2-deoxy-D-glucosyl P2-polyisoprenyl pyrophosphate by calf pancreas microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363053"}
{"pmid": "4363055", "title": "The effect of prostaglandins E1 and E2 on the human erythrocyte as monitored by spin labels.", "content": "The effect of prostaglandins E1 and E2 on the human erythrocyte as monitored by spin labels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363055"}
{"pmid": "4363054", "title": "Yeast mutants requiring ergosterol as only lipid supplement.", "content": "Yeast mutants requiring ergosterol as only lipid supplement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363054"}
{"pmid": "4363057", "title": "Structural polypeptides of primate derived type C RNA tumor viruses.", "content": "Structural polypeptides of primate derived type C RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363057"}
{"pmid": "4363056", "title": "Mechanism of stimulation of Ca2+ plus Mg2+ -dependent phospodiesterase from rat cerebral cortex by the modulator protein and Ca2+.", "content": "Mechanism of stimulation of Ca2+ plus Mg2+ -dependent phospodiesterase from rat cerebral cortex by the modulator protein and Ca2+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363056"}
{"pmid": "4363059", "title": "The epidermal disorder in lichen planus: an in vitro study.", "content": "The epidermal disorder in lichen planus: an in vitro study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363059"}
{"pmid": "4363060", "title": "Deoxynucleotide-polymerizing enzymes in normal and malignant human cells.", "content": "Deoxynucleotide-polymerizing enzymes in normal and malignant human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363060"}
{"pmid": "4363061", "title": "The delayed and lasting rejection of mammary adenocarcinoma cell tumors in DBA-2 mice with use of killed Bordetella pertussis.", "content": "The delayed and lasting rejection of mammary adenocarcinoma cell tumors in DBA-2 mice with use of killed Bordetella pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363061"}
{"pmid": "4363063", "title": "Effect of murine milk samples and human breast tissues on human leukocyte migration indices.", "content": "Effect of murine milk samples and human breast tissues on human leukocyte migration indices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363063"}
{"pmid": "4363062", "title": "Fetal-leukemic antigen of chicken blood cells.", "content": "Fetal-leukemic antigen of chicken blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363062"}
{"pmid": "4363064", "title": "Suppression of SV40 tumors after immunization with group A Streptococcus pyogenes and Bordetella pertussis.", "content": "Suppression of SV40 tumors after immunization with group A Streptococcus pyogenes and Bordetella pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363064"}
{"pmid": "4363065", "title": "Steroid delta 4 -reductase activity in hepatomas of differentgrowth rates.", "content": "Steroid delta 4 -reductase activity in hepatomas of differentgrowth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363065"}
{"pmid": "4363066", "title": "Patterns of excretion of methylated purines in hepatocellular carcinoma.", "content": "Patterns of excretion of methylated purines in hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363066"}
{"pmid": "4363068", "title": "Development of preimplantation rabbit embryos in vivo and in vitro. I. An ultrastructural comparison.", "content": "Development of preimplantation rabbit embryos in vivo and in vitro. I. An ultrastructural comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363068"}
{"pmid": "4363070", "title": "Intradiem changes of plasma aldosterone, cortisol, corticosterone and growth hormone in sodium restriction.", "content": "Intradiem changes of plasma aldosterone, cortisol, corticosterone and growth hormone in sodium restriction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363070"}
{"pmid": "4363071", "title": "An unusual case of Cushing's syndrome, hilus cell tumor and polycystic ovaries.", "content": "An unusual case of Cushing's syndrome, hilus cell tumor and polycystic ovaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363071"}
{"pmid": "4363072", "title": "Responsiveness of human subjects to human growth hormone: relation to bone age.", "content": "Responsiveness of human subjects to human growth hormone: relation to bone age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363072"}
{"pmid": "4363073", "title": "Correlations of serum triglyceride and prebetalipoprotein levels to the severity of spontaneous diabetes in Macaca nigra.", "content": "Correlations of serum triglyceride and prebetalipoprotein levels to the severity of spontaneous diabetes in Macaca nigra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363073"}
{"pmid": "4363074", "title": "Effect of chlorpropamide on osmotic water flow across toad bladder and the response to vasopressin, theophylline and cyclic AMP.", "content": "Effect of chlorpropamide on osmotic water flow across toad bladder and the response to vasopressin, theophylline and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363074"}
{"pmid": "4363058", "title": "Morphologic variations of a cell strain transformed by simian papovavirus SV40 and cloned serially.", "content": "Morphologic variations of a cell strain transformed by simian papovavirus SV40 and cloned serially.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363058"}
{"pmid": "4363075", "title": "Thyroid hormone action: demonstration of putative nuclear receptors in human lymphocytes.", "content": "Thyroid hormone action: demonstration of putative nuclear receptors in human lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363075"}
{"pmid": "4363076", "title": "Big renin: a possible prohormone in kidney and plasma of a patient with Wilm's tumor.", "content": "Big renin: a possible prohormone in kidney and plasma of a patient with Wilm's tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363076"}
{"pmid": "4363077", "title": "Bioavailability of different sources of dietary iron fed to Pitman-Moore miniature pigs.", "content": "Bioavailability of different sources of dietary iron fed to Pitman-Moore miniature pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363077"}
{"pmid": "4363078", "title": "Body fluid and electrolyte balance during estrogen therapy of prostatic cancer.", "content": "Body fluid and electrolyte balance during estrogen therapy of prostatic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363078"}
{"pmid": "4363079", "title": "Webbed penis.", "content": "Webbed penis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363079"}
{"pmid": "4363067", "title": "Persistence and expression of the herpes simplex virus type 2 genome in cervical tumor cells.", "content": "Persistence and expression of the herpes simplex virus type 2 genome in cervical tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363067"}
{"pmid": "4363080", "title": "Regulation of phosphorylase B to A conversion in muscle.", "content": "Regulation of phosphorylase B to A conversion in muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363080"}
{"pmid": "4363083", "title": "Excretion and degradation of exogenous adenosine 3',5'-monophosphate by isolated perfused rat kidney.", "content": "Excretion and degradation of exogenous adenosine 3',5'-monophosphate by isolated perfused rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363083"}
{"pmid": "4363081", "title": "Adenosine-elicited accumulation of cyclic AMP in brain slices: potentiation by agents which inhibit uptake of adenosine.", "content": "Adenosine-elicited accumulation of cyclic AMP in brain slices: potentiation by agents which inhibit uptake of adenosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363081"}
{"pmid": "4363082", "title": "Cartilage cyclic nucleotide phosphodiesterase: inhibition by anti-inflammatory agents.", "content": "Cartilage cyclic nucleotide phosphodiesterase: inhibition by anti-inflammatory agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363082"}
{"pmid": "4363086", "title": "Genetic evidence for SV40 gene function in enhancement of replication of human adenovirus in simian cells.", "content": "Genetic evidence for SV40 gene function in enhancement of replication of human adenovirus in simian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363086"}
{"pmid": "4363085", "title": "Zinc ions inhibit replication of rhinoviruses.", "content": "Zinc ions inhibit replication of rhinoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363085"}
{"pmid": "4363087", "title": "No crossing over between closely linked tumour virus loci in the heterogametic sex of fowl.", "content": "No crossing over between closely linked tumour virus loci in the heterogametic sex of fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363087"}
{"pmid": "4363089", "title": "Prostaglandin-dependent and -independent feedback control of noradrenaline secretion in vasoconstrictor nerves of normotensive human subjects. A preliminary report.", "content": "Prostaglandin-dependent and -independent feedback control of noradrenaline secretion in vasoconstrictor nerves of normotensive human subjects. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363089"}
{"pmid": "4363090", "title": "Temporal discrimination of short intervals of dreamless sleep.", "content": "Temporal discrimination of short intervals of dreamless sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363090"}
{"pmid": "4363091", "title": "Effects of \"short-term\" versus \"long-term\" L-Dopa therapy in parkinsonism on critical flicker frequency.", "content": "Effects of \"short-term\" versus \"long-term\" L-Dopa therapy in parkinsonism on critical flicker frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363091"}
{"pmid": "4363092", "title": "Familial type II hyperlipoproteinaemia. Clinical features and results of treatment in children and young adults.", "content": "Familial type II hyperlipoproteinaemia. Clinical features and results of treatment in children and young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363092"}
{"pmid": "4363098", "title": "Pigment movements in fish melanophores: morphological and physiological studies. 3. The effects of colchicine and vinblastine.", "content": "Pigment movements in fish melanophores: morphological and physiological studies. 3. The effects of colchicine and vinblastine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363098"}
{"pmid": "4363097", "title": "Pigment movements in fish melanophores: morphological and physiological studies.", "content": "Pigment movements in fish melanophores: morphological and physiological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363097"}
{"pmid": "4363100", "title": "Structure and permeability of the septate junction in the kidney sac of Helix pomatia L.", "content": "Structure and permeability of the septate junction in the kidney sac of Helix pomatia L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363100"}
{"pmid": "4363099", "title": "The fine structure of the kidney of Achatina achatina (L).", "content": "The fine structure of the kidney of Achatina achatina (L).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363099"}
{"pmid": "4363101", "title": "Ultrastructure of motor nerve terminals on different types of muscle fibers in the Atlantic hagfish (Myxine glutinosa, L.). Occurrence of round and elongated profiles of synaptic vesicles and dense-core vesicles.", "content": "Ultrastructure of motor nerve terminals on different types of muscle fibers in the Atlantic hagfish (Myxine glutinosa, L.). Occurrence of round and elongated profiles of synaptic vesicles and dense-core vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363101"}
{"pmid": "4363103", "title": "Postnatal development of the lateral vestibular nucleus (Deiters' nucleus) of the rat. A light and electron microscopic study.", "content": "Postnatal development of the lateral vestibular nucleus (Deiters' nucleus) of the rat. A light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363103"}
{"pmid": "4363102", "title": "Total gastrectomy for cancer of the stomach.", "content": "Total gastrectomy for cancer of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363102"}
{"pmid": "4363104", "title": "Conjunctival papillomas in siblings.", "content": "Conjunctival papillomas in siblings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363104"}
{"pmid": "4363105", "title": "Benign mixed tumor of the (palpebral) lacrimal gland presenting as a nodular eyelid lesion.", "content": "Benign mixed tumor of the (palpebral) lacrimal gland presenting as a nodular eyelid lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363105"}
{"pmid": "4363106", "title": "Epithelial inclusion cyst of iris after keratoplasty.", "content": "Epithelial inclusion cyst of iris after keratoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363106"}
{"pmid": "4363107", "title": "Partial REM sleep deprivation, schizophrenia and field articulation.", "content": "Partial REM sleep deprivation, schizophrenia and field articulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363107"}
{"pmid": "4363108", "title": "Physiocochemical properties of low-density lipoproteins of normal human plasma. Evidence for the occurrence of lipoprotein B in associated and free forms.", "content": "Physiocochemical properties of low-density lipoproteins of normal human plasma. Evidence for the occurrence of lipoprotein B in associated and free forms. 1. Low-density (d 1.006-1.063g/ml) lipoproteins from normal human plasma were separated by differential preparative ultracentrifugation into six subfractions. Each low-density (LD) lipoprotein subfraction contained lipoprotein B as the major and lipoproteins A and C as the minor lipoprotein families. 2. Three lipoprotein B subfractions (LP-B), LP-B-III (d 1.019-1.030g/ml), LP-B-IV (d 1.030-1.040g/ml) and LP-B-V (d 1.040-1.053g/ml) were prepared from the corresponding LD lipoprotein subfractions by immunoprecipitating small amounts of lipoproteins A and C. 3. Determination of hydrodynamic properties indicated that LD lipoproteins consisted of three molecular segments characterized by a stepwise change in the molecular weight: LDL-I and LDL-II subfractions (d 1.006-1.019g/ml) with an average mol.wt. of 4.75x10(6), LDL-III (d 1.019-1.030g/ml) with a mol.wt. of 3.99x10(6), and LDL-IV, LDL-V and LDL-VI (d 1.030-1.063g/ml) with a mol.wt. of 2.85x10(6). 4. All three lipoprotein B subfractions had an average mol.wt. of 3.16x10(6). 5. The LDL-I and LDL-II subfractions consisted of lipoprotein B and lipoprotein C families which were present in the form of an association complex. This was isolated from serum by immunoprecipitation with antibodies to lipoprotein B. The complex had a mol.wt. of 4.35x10(6). 6. The results indicate a fundamental difference between the LD lipoprotein subfractions with d 1.006-1.019g/ml and those subfractions with d 1.030-1.063g/ml. In the former, lipoprotein B occurs as a part of an association complex, whereas in the latter it occurs as a separate entity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363108"}
{"pmid": "4363109", "title": "Studies on partially reduced mammalian cytochrome oxidase. Reactions with carbon monoxide and oxygen.", "content": "Studies on partially reduced mammalian cytochrome oxidase. Reactions with carbon monoxide and oxygen. A number of methods were used to prepare a species of mammalian cytochrome oxidase (EC 1.9.3.1, ferrocytochrome c-oxygen oxidoreductase) in which only cytochrome a(3) is reduced and in combination with CO. The kinetics of CO binding by cytochrome a(3) (2+) in this species is significantly different from that exhibited by cytochrome a(3) (2+) in the fully reduced enzyme. The second-order rate constant for combination was 5x10(4)m(-1).s(-1) and the ;off' constant was 3x10(-2)s(-1). The kinetic difference spectra cytochrome a(3) (2+)-cytochrome a(3) (2+)-CO reveal further differences between the mixed-valence and the fully reduced enzyme. The reaction between cytochrome a(3) (2+) and oxygen in the mixed-valence species was followed in flow-flash experiments and reveals a fast, oxygen-dependent (8x10(7)m(-1).s(-1) at low oxygen) rate followed by a slow process, whose rate is independent of oxygen but whose amplitude is dependent on [O(2)]. The fast oxygen-dependent reaction yields as the first product the so-called ;oxygenated' enzyme. We conclude from these experiments that the ligand-binding behaviour of cytochrome a(3) depends on the redox state of its partners, a fact which represents clear evidence for site-site interaction in this enzyme. The fact that oxygen reacts rapidly with this enzyme species in which only one component, namely cytochrome a(3), is reduced represents clear and unequivocal evidence that this is indeed the O(2)-binding site in cytochrome oxidase and may indicate that reduction of oxygen can proceed via single electron steps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363109"}
{"pmid": "4363110", "title": "Separation at neutral pH value of 32P-labelled proteins in a membrane preparation from ox brain. Partial characterization of component of the sodium-plus-potassium ion-activited adenosine triphosphatase.", "content": "Separation at neutral pH value of 32P-labelled proteins in a membrane preparation from ox brain. Partial characterization of component of the sodium-plus-potassium ion-activited adenosine triphosphatase. 1. Ox brain microsomal fractions were labelled with [(32)P]ATP in the presence of Na(+) and the reaction was stopped with sodium dodecyl sulphate. The Na(+)-dependent bound phosphate was isolated on Sephadex G-25 and by acetone precipitation. The bound phosphate isolated under these neutral conditions was labile to hydroxylamine and gave the same pH profile of hydrolysis as that isolated by precipitation with strong acids. 2. When membrane protein was labelled with [(32)P]ATP, solubilized with sodium dodecyl sulphate and fractionated on Sepharose 6B, the Na(+)-dependent label emerged in a peak corresponding to protein of molecular weight 570000-580000. On fractionation of this protein peak on polyacrylamide gels containing detergent and urea, the Na(+)-dependent label occurred in a single band corresponding to a protein of molecular weight 102000. 3. Fractionation on Sepharose 6B of protein labelled with [(32)P]ATP in the absence of Na(+) revealed three labelled peaks, one of which corresponded in position to the Na(+)-dependent label. Electrophoresis of this peak material on polyacrylamide gels showed that most of the label occurred in two fast-running bands. Cyclic AMP stimulated the labelling in these two bands, but had no effect on the labelling of the band corresponding in position to the Na(+)-dependent label. 4. Di-isopropyl [(32)P]phosphorofluoridate also labelled the band corresponding to the Na(+)-dependent label on gel electrophoresis. The labelling of this band by the reagent was inhibited by 50-60% by 3mm-ATP, but there was no evidence to suggest that the group labelled is normally phosphorylated by ATP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363110"}
{"pmid": "4363111", "title": "The molecular basis for biological inactivation of nucleic acids. The action of methylating agents on the ribonucleic acid-containing bacteriophage R17.", "content": "The molecular basis for biological inactivation of nucleic acids. The action of methylating agents on the ribonucleic acid-containing bacteriophage R17. 1. The inactivation of an RNA-containing bacteriophage after reaction with four methylating agents was studied. Measurements of the extent of methylation of the RNA and of the nature and amounts of the various reaction products were made. In experiments with dimethyl sulphate and methyl methanesulphonate inactivation can be quantitatively accounted for by methylation at two of the positions involved in hydrogen bonding: N-1 of adenine and N-3 of cytosine. In experiments with N-methyl-N-nitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine methylation at N-1 of adenine and N-3 of cytosine accounts for only about one-half of the observed inactivation. Scission of the RNA chain during reaction accounts for a further 20% of the inactivation. To account for the remainder it seems necessary to postulate that formation of O(6)-methylguanine constitutes a lethal lesion. 2. Breaks in the RNA chain formed on reaction with the nitroso derivatives presumably result from methylation of the phosphate diester group followed by hydrolysis of the unstable triester thus formed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363111"}
{"pmid": "4363112", "title": "The reaction of alkylating agents with bacteriophage R17. Biological effects of phosphotriester formation.", "content": "The reaction of alkylating agents with bacteriophage R17. Biological effects of phosphotriester formation. The extent of biological inactivation and of the degradation of the RNA after reaction of bacteriophage R17 with ethyl methanesulphonate, isopropyl methanesulphonate and N-ethyl-N-nitrosourea was studied. Formation of breaks in the RNA chain probably results from hydrolysis of phosphotriesters formed in the alkylation reactions. Near neutral pH the ethyl and isopropyl phosphotriesters are sufficiently stable for the kinetics of the hydrolysis reaction to be followed. Results indicate that the rate of hydrolysis increases rapidly as the pH is raised. The evidence shows that a phosphotriester group does not itself constitute a lethal lesion. The extent of phosphotriester formation by the different agents is discussed in terms of reaction mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363112"}
{"pmid": "4363114", "title": "Fluorescence studies of protein-sterol relationships in human plasma lipoproteins.", "content": "Fluorescence studies of protein-sterol relationships in human plasma lipoproteins. Cholesta-5,7,9(11)-trien-3beta-ol and its oleate ester were incorporated into human low-density lipoprotein and reconstituted high-density lipoprotein. The unesterified sterol was more efficient than its ester in quenching tryptophan fluorescence, especially in low-density lipoprotein. The results, which indicate that in such lipoproteins unesterified sterols are more closely associated with peptide than are esterified sterols, are used to assess possible structures for the lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363114"}
{"pmid": "4363113", "title": "A specific collagenase from rabbit fibroblasts in monolayer culture.", "content": "A specific collagenase from rabbit fibroblasts in monolayer culture. 1. Explants of rabbit skin and synovium in tissue culture secreted a specific collagenase into their culture media. Primary cultures of fibroblast-like cells, which were obtained from these tissues and maintained in culture for up to 14 subculture passages, also secreted high activities of a specific collagenase into serum-free culture medium. Secretion of enzyme activity from the cell monolayer was at constant rate for over 100h and continued for up to 8 days in serum-free culture medium. The enzymic activity released was proportional to the number of cells in the monolayer. 2. The fibroblast collagenase was maximally active between pH7 and 8. At 24 degrees C the collagenase decreased the viscosity of collagen in solution by 60%. The collagen molecule was cleaved into three-quarters and one-quarter length fragments as demonstrated by electron microscopy of segment-long-spacing crystallites (measured as native collagen molecules aligned with N-termini together along the long axis), and by polyacrylamide-gel electrophoresis of the denatured products. The collagenase hydrolysed insoluble collagen, reconstituted collagen fibrils and gelatin, but had no effect on haemoglobin or Pz-Pro-Leu-Gly-Pro-d-Arg (where Pz=4-phenylazobenzyloxycarbonyl). 3. The fibroblast collagenase was partially purified by gel filtration and the molecular weight was estimated as 38000. The activity of the partially purified enzyme was stimulated by 4-chloromercuribenzoate, inhibited by EDTA, cysteine, 1,10-phenanthroline and serum, but was unaffected by di-isopropyl phosphorofluoridate, Tos-LysCH(2)Cl and pepstatin. 4. Long-term cell cultures originating from rabbit skin or synovium from rabbits with experimentally induced arthritis also secreted specific collagenase. Human fibroblasts released only very small amounts of collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363113"}
{"pmid": "4363115", "title": "Studies on the topography of the fat cell plasma membrane.", "content": "Studies on the topography of the fat cell plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363115"}
{"pmid": "4363116", "title": "Interaction of actin with spin-labeled heavy meromyosin in the presence of nucleotides.", "content": "Interaction of actin with spin-labeled heavy meromyosin in the presence of nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363116"}
{"pmid": "4363117", "title": "Exchangeability of bicarbonate specifically bound to transferrin.", "content": "Exchangeability of bicarbonate specifically bound to transferrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363117"}
{"pmid": "4363118", "title": "Proton magnetic resonance study of angiotensin II (Asn1Va15) in aqueous solution.", "content": "Proton magnetic resonance study of angiotensin II (Asn1Va15) in aqueous solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363118"}
{"pmid": "4363119", "title": "Purification and characterization of a steroid receptor from chick embryo liver.", "content": "Purification and characterization of a steroid receptor from chick embryo liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363119"}
{"pmid": "4363120", "title": "A circular dichroism study of the secondary structure of bradykinin.", "content": "A circular dichroism study of the secondary structure of bradykinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363120"}
{"pmid": "4363121", "title": "Selective incorporation of host cell methionyl-transfer RNA by RNA tumor viruses.", "content": "Selective incorporation of host cell methionyl-transfer RNA by RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363121"}
{"pmid": "4363122", "title": "Inactivation of aminoacyl-tRNA synthetases by amino acid chloromethylketones.", "content": "Inactivation of aminoacyl-tRNA synthetases by amino acid chloromethylketones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363122"}
{"pmid": "4363123", "title": "Drug-induced renal medullary necrosis. II. Mode of calcification in the kidney.", "content": "Drug-induced renal medullary necrosis. II. Mode of calcification in the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363123"}
{"pmid": "4363125", "title": "Dibutyryl cyclic AMP: increase in viral particles associated with morphologic changes in leukemic cells.", "content": "Dibutyryl cyclic AMP: increase in viral particles associated with morphologic changes in leukemic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363125"}
{"pmid": "4363124", "title": "Dietary induced hyperbetalipoproteinemia in chimpanzees: comparison to the human hyperlipoproteinemia.", "content": "Dietary induced hyperbetalipoproteinemia in chimpanzees: comparison to the human hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363124"}
{"pmid": "4363126", "title": "Phagocytosis of injured hepatocytes following inoculation with encephalomyocarditis virus.", "content": "Phagocytosis of injured hepatocytes following inoculation with encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363126"}
{"pmid": "4363127", "title": "Lysosomes of the arterial wall. II. Subcellular fractionation of aortic cells from rabbits with experimantal atheroma.", "content": "Lysosomes of the arterial wall. II. Subcellular fractionation of aortic cells from rabbits with experimantal atheroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363127"}
{"pmid": "4363128", "title": "Mast cells: extended lifespan and lack of granule turnover under normal in vivo conditions.", "content": "Mast cells: extended lifespan and lack of granule turnover under normal in vivo conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363128"}
{"pmid": "4363148", "title": "Consideration of some problems in dosimetry and radiobioloby of stopped negative pions.", "content": "Consideration of some problems in dosimetry and radiobioloby of stopped negative pions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363148"}
{"pmid": "4363149", "title": "Timing of ovulation in a sterility clinic.", "content": "Timing of ovulation in a sterility clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363149"}
{"pmid": "4363150", "title": "\"Uterine progesterone system (U.P.S.)\": a new form of intrauterine contraception. Preliminary report.", "content": "\"Uterine progesterone system (U.P.S.)\": a new form of intrauterine contraception. Preliminary report. This preliminary study of the \"uterine progesterone system\" (UPS), a new contraceptive agent, on 32 women for a total of 200 woman-months was very effective.  There were no side effects, no expulsions, no pregnancies, and no abnormalities in the metabolism of fats, carbohydrates and protein.  The UPS is in the shape of a T which is easily inserted and easily removed.  It has a biocompatible polymer outer membrane containing an inner core of progesterone suspension.  The UPS releases 50 mcg of progesterone per 24 hours for more than a year.  The local release of steroids interferes with fertility but does not affect the hypothalamic-pituitary-ovarian axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363150"}
{"pmid": "4363151", "title": "Immunochemical studies on human seminal plasma. 3. Ultracentrifugal studies on human seminal plasma and a purified fraction.", "content": "Immunochemical studies on human seminal plasma. 3. Ultracentrifugal studies on human seminal plasma and a purified fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363151"}
{"pmid": "4363152", "title": "Daily urinary excretion of follicle stimulating (FSH) and luteinizing hormone (LH) immediately after menarche.", "content": "Daily urinary excretion of follicle stimulating (FSH) and luteinizing hormone (LH) immediately after menarche.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363152"}
{"pmid": "4363153", "title": "Hydrotubation.", "content": "Hydrotubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363153"}
{"pmid": "4363154", "title": "Effect of HCG on plasma levels of estrogens and progesterone during the luteal phase of the menstrual cycle in rhesus monkeys (Macaca mulatta). Stimulation of sex steroid production in Rhesus monkeys.", "content": "Effect of HCG on plasma levels of estrogens and progesterone during the luteal phase of the menstrual cycle in rhesus monkeys (Macaca mulatta). Stimulation of sex steroid production in Rhesus monkeys. To study the plasma patterns of estrogen and progesterone under gonadotropic stimulation simulating early pregnancy, 4 normal female rhesus monkeys (Macaca mulatta) were injected intramuscularly with 50-250 IU of human chorionic gonadotropin  (HCG) for 5-10 days during the luteal phase of their menstrual cycle.  Plasma levels of estrogen and progesterone were measured by radioimmunoassay of blood samples taken before and after the HCG injections.  The exogenous HCG was found to prolong the life span of the corpus luteum and extended the length of the luteal phase in direct relation to the length of HCG treatment.  Within 6 hours after the first HCG injection, a 10-fold increase in plasma progesterone was found in all 4 monkeys, and plasma progesterone levels remained comparatively high for 4-5 days after the first injection.  The plasma levels of estrone and estradiol were significantly higher than pretreatment levels and normal luteal phase levels during and after HCG injection, with estrone predominating over estradiol levels.  It is concluded that HCG injections in the luteal phase stimulate estrogen and progesterone production, with progesterone increasing before estrogen, but with the increased estrogen levels being maintained for longer periods of time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363154"}
{"pmid": "4363155", "title": "Immunological similarity of placenta in human and Rhesus monkey.", "content": "Immunological similarity of placenta in human and Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363155"}
{"pmid": "4363156", "title": "Post \"pill\" amenorrhoea.", "content": "Post \"pill\" amenorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363156"}
{"pmid": "4363157", "title": "Zinc and magnesium in human spermatozoa from different fractions of split ejaculates.", "content": "Zinc and magnesium in human spermatozoa from different fractions of split ejaculates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363157"}
{"pmid": "4363158", "title": "Long-term therapy with low-dose cisclomiphene in male infertility: effects on semen, serum FSH, LH, testosterone ond estradiol, and carbohydrate tolerance.", "content": "Long-term therapy with low-dose cisclomiphene in male infertility: effects on semen, serum FSH, LH, testosterone ond estradiol, and carbohydrate tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363158"}
{"pmid": "4363159", "title": "In vitro release and uptake of zinc and magnesium by human spermatozoa.", "content": "In vitro release and uptake of zinc and magnesium by human spermatozoa. Changes in the zinc and magnesium content of human spermatozoa with time have been followed over the first 24 hours after ejaculation.  Magnesium did not change but marked alternations were noted for the zinc concentration.  During the first hour there was a significant decrease followed by a \"steady state\" for 2 hours.  Then a significant increase during the following 4 hours was recorded.  Between 7 and 24 hours after ejaculation there was no further increase in the zinc concentration, nor did addition of 100 ug zinc per ml seminal plasma after 24 hours alter the sperm content of this ion.  The importance of the seminal plasma for sperm uptake of zinc could be demonstrated.  One subject presented semen specimens in which the uptake of zinc by the spermatozoa was very rapid and higher than that in the others.  The seminal plasma from this man had biochemical signs of a markedly decreased prostate function.  Incubation of normal spermatozoa in this seminal plasma for 4 hours increased their zinc content 3 times over the control values.  The observation that the secretory function of the accessory genital glands can influence functional properties of the spermatozoa seems of principal interest from many points of view.  Further studies along the same line may give leads to new male contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363159"}
{"pmid": "4363160", "title": "Sperm antibody production in female sterility.", "content": "Sperm antibody production in female sterility. A review of the immunological implications in reproductive physiology is presented.  Although attempts have been made to ascribe the antigenicity of semen to individual components, it has not been possible to isolate the human semen antigen responsible for infertility.  In monkeys total ejaculates and seminal plasma have shown higher antigenicity than washed spermatozoa.  In bulls some evidence of such antigens have been found in the seminal plasma.  They are iron-binding proteins resembling lactoferrin.  Most investigators have found no evidence for any participation of the ABO blood group antigens in cases of sterility.  On the surface of human spermatozoa histo-incompatibility antigens have been detected.  Transplantation antigens may be related to sterility.  However, an immulogic tolerance of the maternal organism exists against the genetically foreign fetal tissue.  Autoimmune spermagglutinating antibodies have been detected in the sera and in the seminal plasma of males with sterility.  An obstruction of the seminal pathways may facilitate the production of such antibodies against retained sperm.  Isoimmunity in females against seminal components has been shown in cases of sterility; however, fertile women have also been shown to have such conditions.  In a group of infertile women spermagglutination activity was detected in 7.5% of cases.  In another series of 46 cases with primary unexplained infertility agglutinating antibodies were found in 17.4%.  Other investigators have also reported higher rates than the authors.  The sperm immobilization test seems to be more sensitive than the agglutination test.  No sera were found positive with both tests.  With immunofluorescent techniques humoral sperm antibodies have been found to be the IgM and IgG fractions.  Each acts on a different part of the spermatozoa.  The only promising therapy against humoral sperm antibodies is avoidance of sperm contact over a long period of time.  Reported results have been conflicting.  Cortisone did not improve the result.  Desensitization or immunosuppresive efforts are of uncertain value.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363160"}
{"pmid": "4363161", "title": "Human vascular endothelial cells in culture. Growth and DNA synthesis.", "content": "Human vascular endothelial cells in culture. Growth and DNA synthesis. Human endothelial cells, obtained by collagenase treatment of term umbilical cord veins, were cultured using Medium 199 supplemented with 20% fetal calf serum. Small clusters of cells initially spread on plastic or glass, coalesced and grew to form confluent monolayers of polygonal cells by 7 days. Cells in primary and subcultures were identified as endothelium by the presence of Weibel-Palade bodies by electron microscopy. A morphologically distinct subpopulation of cells contaminating some primary endothelial cultures was selectively subcultured, and identified by ultrastructural criteria as vascular smooth muscle. Autoradiography of endothelial cells after exposure to [(3)H]thymidine showed progressive increases in labeling in growing cultures beginning at 24 h. In recently confluent cultures, labeling indices were 2.4% in central closely packed regions, and 53.2% in peripheral growing regions. 3 days after confluence, labeling was uniform, being 3.5 and 3.9% in central and peripheral areas, respectively. When small areas of confluent cultures were experimentally \"denuded,\" there were localized increases in [(3)H]thymidine labeling and eventual reconstitution of the monolayer. Liquid scintillation measurements of [(3)H]thymidine incorporation in primary and secondary endothelial cultures in microwell trays showed a similar correlation of DNA synthesis with cell density. These data indicate that endothelial cell cultures may provide a useful in vitro model for studying pathophysiologic factors in endothelial regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363161"}
{"pmid": "4363163", "title": "Haemagglutinating antigen prepared from Yaba-1 virus (strain Lednice-110) by ultrasonic disintegration.", "content": "Haemagglutinating antigen prepared from Yaba-1 virus (strain Lednice-110) by ultrasonic disintegration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363163"}
{"pmid": "4363162", "title": "Unconventional nucleotide analogues. Synthesis of N-substituted 3-(adenin-9-yl)pyrrolidin-2-ones.", "content": "Unconventional nucleotide analogues. Synthesis of N-substituted 3-(adenin-9-yl)pyrrolidin-2-ones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363162"}
{"pmid": "4363164", "title": "Cystosarcoma phylloides.", "content": "Cystosarcoma phylloides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363164"}
{"pmid": "4363165", "title": "Chiropractic: a challenge for health education.", "content": "Chiropractic: a challenge for health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363165"}
{"pmid": "4363166", "title": "Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats.", "content": "Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363166"}
{"pmid": "4363168", "title": "Virus productive transformation of marsupial cells by Schmidt-Ruppin strain of RSV.", "content": "Virus productive transformation of marsupial cells by Schmidt-Ruppin strain of RSV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363168"}
{"pmid": "4363169", "title": "DNA synthesis in \"nuclear monolayers\" from BSC-1 cells infected with herpes virus.", "content": "DNA synthesis in \"nuclear monolayers\" from BSC-1 cells infected with herpes virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363169"}
{"pmid": "4363170", "title": "Oestradiol inhibition of collagenase role in uterine involution.", "content": "Oestradiol inhibition of collagenase role in uterine involution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363170"}
{"pmid": "4363171", "title": "With reference to the effect of pituitary hormones on lymphocyte blastogenesis in cell-culture.", "content": "With reference to the effect of pituitary hormones on lymphocyte blastogenesis in cell-culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363171"}
{"pmid": "4363178", "title": "Non-simultaneous bilateral breast carcinoma.", "content": "Non-simultaneous bilateral breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363178"}
{"pmid": "4363179", "title": "Measurement of hepatic blood flow in man.", "content": "Measurement of hepatic blood flow in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363179"}
{"pmid": "4363193", "title": "The reaction of the preoptic nucleus of Xenopus laevis to osmotic stimulation. An enzyme cytochemical investigation.", "content": "The reaction of the preoptic nucleus of Xenopus laevis to osmotic stimulation. An enzyme cytochemical investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363193"}
{"pmid": "4363197", "title": "Cyclic AMP as a regulator of thymidine kinase.", "content": "Cyclic AMP as a regulator of thymidine kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363197"}
{"pmid": "4363198", "title": "Transformed estrogen receptor in the regulation of RNA synthesis in uterine nuclei.", "content": "Transformed estrogen receptor in the regulation of RNA synthesis in uterine nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363198"}
{"pmid": "4363199", "title": "Alterations of complex lipid metabolism in tumorigenic virus transformed cell lines.", "content": "Alterations of complex lipid metabolism in tumorigenic virus transformed cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363199"}
{"pmid": "4363200", "title": "Functional studies of polysome-membrane interactions in vitro.", "content": "Functional studies of polysome-membrane interactions in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363200"}
{"pmid": "4363201", "title": "A study of the hormonal control in vitro of Na+-K+ activated ATPase of isolated liver plasma membrane.", "content": "A study of the hormonal control in vitro of Na+-K+ activated ATPase of isolated liver plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363201"}
{"pmid": "4363203", "title": "Some regulatory mechanisms in the synthesis of urea in the mammalian liver.", "content": "Some regulatory mechanisms in the synthesis of urea in the mammalian liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363203"}
{"pmid": "4363202", "title": "Glycogen synthetases and phosphorylases in rat hepatomas.", "content": "Glycogen synthetases and phosphorylases in rat hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363202"}
{"pmid": "4363204", "title": "Ordered and specific pattern of gene expression in neoplasia.", "content": "Ordered and specific pattern of gene expression in neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363204"}
{"pmid": "4363206", "title": "Role of gastrin in hypersecretory disorders in man.", "content": "Role of gastrin in hypersecretory disorders in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363206"}
{"pmid": "4363207", "title": "Antiviral chemotherapy.", "content": "Antiviral chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363207"}
{"pmid": "4363209", "title": "Vitamin D metabolism.", "content": "Vitamin D metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363209"}
{"pmid": "4363208", "title": "Crystal deposition joint disease.", "content": "Crystal deposition joint disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363208"}
{"pmid": "4363210", "title": "The cell surface and malignant transformation.", "content": "The cell surface and malignant transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363210"}
{"pmid": "4363212", "title": "Properties of alcohol dehydrogenase isozymes in a strain of Drosophila melanogaster homozygous for the Adh-slow allele.", "content": "Properties of alcohol dehydrogenase isozymes in a strain of Drosophila melanogaster homozygous for the Adh-slow allele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363212"}
{"pmid": "4363211", "title": "Sulfonylureas and the heart.", "content": "Sulfonylureas and the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363211"}
{"pmid": "4363213", "title": "Effects of morphine on the gluconeogenic enzymes from rat liver in vivo.", "content": "Effects of morphine on the gluconeogenic enzymes from rat liver in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363213"}
{"pmid": "4363214", "title": "Absence of an effect of histamine, noradrenaline and depolarizing agents on the levels of adenosine 3', 5'-monophosphate in nerve endings isolated from cerebral cortex.", "content": "Absence of an effect of histamine, noradrenaline and depolarizing agents on the levels of adenosine 3', 5'-monophosphate in nerve endings isolated from cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363214"}
{"pmid": "4363216", "title": "Effect of collagenase pretreatment on choline and acetylcholine release from slices of bovine superior cervical sympathetic ganglia.", "content": "Effect of collagenase pretreatment on choline and acetylcholine release from slices of bovine superior cervical sympathetic ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363216"}
{"pmid": "4363215", "title": "Effect of lithium on prostaglandin F1-stimulated adenylate cyclase activity of human platelets.", "content": "Effect of lithium on prostaglandin F1-stimulated adenylate cyclase activity of human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363215"}
{"pmid": "4363217", "title": "Inhibition of cAMP phosphodiesterase by disodium cromoglycate.", "content": "Inhibition of cAMP phosphodiesterase by disodium cromoglycate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363217"}
{"pmid": "4363221", "title": "Percutaneous trigeminal tractotomy. Variations in delineation of the obex using emulsified Pantopaque.", "content": "Percutaneous trigeminal tractotomy. Variations in delineation of the obex using emulsified Pantopaque.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363221"}
{"pmid": "4363220", "title": "The effects of inhaled beclomethasone dipropionate (Becotide) and sodium cromoglycate on asthmatic reactions to provocation tests.", "content": "The effects of inhaled beclomethasone dipropionate (Becotide) and sodium cromoglycate on asthmatic reactions to provocation tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363220"}
{"pmid": "4363222", "title": "A radioautographic study on the mechanisms by which adrenal glucocorticoids play their permissive role in the biological activity of cyclic AMP in the liver cell.", "content": "A radioautographic study on the mechanisms by which adrenal glucocorticoids play their permissive role in the biological activity of cyclic AMP in the liver cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363222"}
{"pmid": "4363223", "title": "On the activity of cathepsin C in human embryonic kidney cell cultures infected with Herpesvirus hominis (Herpes simplex).", "content": "On the activity of cathepsin C in human embryonic kidney cell cultures infected with Herpesvirus hominis (Herpes simplex).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363223"}
{"pmid": "4363224", "title": "Inhibition of beef heart and rat brain nucleoside-3':5'-monophosphate phosphodiesterase by 3beta-14-dihydroxy-21-oxo-23-desoxo-5-beta-card-20(22)-enolide 3-acetate (AY-17,605) and structurally related compounds.", "content": "Inhibition of beef heart and rat brain nucleoside-3':5'-monophosphate phosphodiesterase by 3beta-14-dihydroxy-21-oxo-23-desoxo-5-beta-card-20(22)-enolide 3-acetate (AY-17,605) and structurally related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363224"}
{"pmid": "4363226", "title": "Oncogenic viruses in the thrombocytopenic stage of experimental HIPA-plasmacytoma.", "content": "Oncogenic viruses in the thrombocytopenic stage of experimental HIPA-plasmacytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363226"}
{"pmid": "4363227", "title": "Selective potentiating effects of metal ions on vasopressin.", "content": "Selective potentiating effects of metal ions on vasopressin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363227"}
{"pmid": "4363229", "title": "Leukocytosis-promoting factor of Bordetella pertussis. 3. Its identity with protective antigen.", "content": "Leukocytosis-promoting factor of Bordetella pertussis. 3. Its identity with protective antigen. Leukocytosis-promoting factor (LPF) was purified from the supernatant of a 5-day liquid culture of Bordetella pertussis strains Tohama and no. 134. The preparations appeared to be filamentous molecules (2 by 40 nm) and contained histamine-sensitizing and hemagglutinin activities in addition to leukocytosis-promoting activity. Active protection tests in mice demonstrated strong protective activities of 80 international protective units per mg of protein in LPF preparations of each strain toxoided by mild Formalin treatment. Passive protection tests in mice with anti-LPF sera indicated that anti-LPF is one of the protective antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363229"}
{"pmid": "4363230", "title": "Delayed-type hypersensitivity and immunity against aerogenic tuberculosis in guinea pigs.", "content": "Delayed-type hypersensitivity and immunity against aerogenic tuberculosis in guinea pigs. In experiments described herein, it was observed that guinea pigs with delayed-type hypersensitivity to tuberculoproteins under various experimental conditions, with or without passive transfer of serum from immune donors, manifested no acquired immunity against aerogenically induced tuberculosis. These results are discussed in relation to the previous observations of other investigators and to the general problem of cellular hypersensitivity and immunity against facultative intracellular bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363230"}
{"pmid": "4363231", "title": "Glycolysis during early infection of feline and human cells with feline leukemia virus.", "content": "Glycolysis during early infection of feline and human cells with feline leukemia virus. A 30 to 40% increase in glucose uptake and lactic acid production was observed during a 48-h period immediately following inoculation of feline fibroblasts and HEp-2 cells with feline leukemia virus. There was no evidence of morphological alterations in either cell type. Immunofluorescent procedures to detect feline leukemia virus group-specific antigen revealed that the feline and HEp-2 cells were infected, whereas the antigen was not found in parallel cultures of uninoculated cells. Increased glycolysis depends upon the physiological state of the host cell and was not observed with infected stationary-phase cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363231"}
{"pmid": "4363233", "title": "Anti-cardiolipin and anti-phosphatidylglycerol antibodies prepared against bacterial phospholipids.", "content": "Anti-cardiolipin and anti-phosphatidylglycerol antibodies prepared against bacterial phospholipids. Anti-phosphatidylglycerol and anti-cardiolipin antisera were prepared in rabbits by using phospholipids purified from Micrococcus lysodeikticus. Anti-phosphatidylglycerol antibodies were found in antisera when either phosphatidylglycerol or cardiolipin were used as immunogens, but adsorption studies indicated they were not similar. Antibodies which reacted with phosphatidylinositol and phosphatidic acid were also found in the anti-cardiolipin antiserum. Structures of the antigenic groups in phosphatidylglycerol and cardiolipin are suggested from cross-reaction and adsorption studies. Adsorption studies with pure phospholipid antigens indicated the importance of the spacial orientation of phospholipid haptens for immunological reactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363233"}
{"pmid": "4363232", "title": "Physicochemical fractionation of extracellular cornea-damaging proteases of Pseudomonas aeruginosa.", "content": "Physicochemical fractionation of extracellular cornea-damaging proteases of Pseudomonas aeruginosa. Fractionation of the culture supernatant fluids of a cornea-virulent strain of Pseudomonas aeruginosa by ammonium sulfate precipitation, diafiltration, isoelectric focusing, ion-exchange chromatography, gel filtration, and sucrose density gradient centrifugation failed to separate the rabbit cornea-damaging activity and the in vitro protease activity of the preparations. Three proteases having similar molecular weights (approximately 20,000) and isoelectric points of approximately 4.6, 5.8, and 8.8 were obtained free of detectable amounts of other known extracellular pseudomonal enzymes. Heating a mixture of the three proteases for 15 min at 80 C resulted in complete loss of protease and cornea-damaging activities. The sterile culture filtrate of a nonproteolytic but lethal toxin-producing strain of P. aeruginosa did not contain cornea-damaging activity. Cultivation of the proteolytic strain in broth containing 4.7% ammonium sulfate yielded a culture supernatant fluid free of protease and cornea-damaging activities. The results obtained support the conclusion that a cornea-virulent strain of P. aeruginosa can produce, in vitro, at least three different extracellular proteases capable of eliciting rapid and extensive damage to rabbit corneas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363232"}
{"pmid": "4363235", "title": "Mutation in Shigella flexneri resulting in loss of ability to penetrate HeLa cells and loss of glycerol kinase activity.", "content": "Mutation in Shigella flexneri resulting in loss of ability to penetrate HeLa cells and loss of glycerol kinase activity. A colonial variant of a virulent Shigella flexneri 2a has lost both virulence and glycerol kinase activity. It also has several other altered characteristics: lowered ability to oxidize tricarboxylic acid cycle intermediates, increased electrophoretic mobility, and decreased sensitivity to sodium lauryl sulfate. Genetic analysis has revealed that the gene governing glycerol kinase activity in Shigella has a different chromosomal locus than that from Escherichia coli. Furthermore, transduction of the Shigella glycerol kinase gene (glp K) into the avirulent Shigella strain can restore the ability to penetrate HeLa cells, whereas the gene from E. coli cannot. About half of the glp K mutants lose this ability, and only about half of the revertants of an avirulent glp K mutant regain it. This indicates that more than one gene affects glycerol kinase activity in Shigella, only one of which is associated with penetration. Glycerol kinase activity is closely correlated with changes in electrophoretic mobility, but does not appear to have any relationship to sodium lauryl sulfate sensitivity nor to the oxidation of tricarboxylic acid cycle intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363235"}
{"pmid": "4363236", "title": "Evidence that neurons harbor latent herpes simplex virus.", "content": "Evidence that neurons harbor latent herpes simplex virus. The cell type(s) harboring latent herpes simplex virus in the spinal ganglia of mice was investigated. Taken together, results from immunofluorescence, electron microscopic, autoradiographic, and in situ nucleic acid hybridization methods suggest strongly that, in mice, latent virus is maintained in neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363236"}
{"pmid": "4363234", "title": "Cross-protection between group B arboviruses: resistance in mice to Japanese B encephalitis and St. Louis encephalitis viruses induced by Dengue virus immunization.", "content": "Cross-protection between group B arboviruses: resistance in mice to Japanese B encephalitis and St. Louis encephalitis viruses induced by Dengue virus immunization. Albino Swiss mice, immunized with any of several types and strains of dengue viruses, were afforded substantial protection against peripheral Japanese B encephalitis or St. Louis encephalitis virus challenge. Dengue-2 (New Guinea \"C\")-immunized mice showed, 10 and 20 weeks after immunization, undiminished resistance with concomitant cyclophosphamide treatment and virus challenge. Examination of the effects of immunization on Japanese B encephalitis virus pathogenesis, after virus challenge with concomitant cyclophosphamide treatment, indicated that protection was associated with decreased viremia and virtually no virus replication in the brain as compared with controls. These effects could be demonstrated before detection of any neutralizing antibody to the challenge virus. From the applied aspect, the data support the hypothesis, based on epidemiological evidence and experiments in hamsters, that prior exposure of man to dengue viruses can confer some degree of protection against Japanese B encephalitis or St. Louis encephalitis disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363234"}
{"pmid": "4363238", "title": "Pleomorphic adenoma of the thyroid containing salivary gland cells with pseudocartilage and myoepithelial cells.", "content": "Pleomorphic adenoma of the thyroid containing salivary gland cells with pseudocartilage and myoepithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363238"}
{"pmid": "4363239", "title": "Preparation and use of surface-modified adsorbents in clean-up techniques for pesticide residue analysis.", "content": "Preparation and use of surface-modified adsorbents in clean-up techniques for pesticide residue analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363239"}
{"pmid": "4363241", "title": "Horny cell formation in the epidermis of Rana pipiens.", "content": "Horny cell formation in the epidermis of Rana pipiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363241"}
{"pmid": "4363240", "title": "Bilateral mixed tumors occurring simultaneously in major and minor salivary glands.", "content": "Bilateral mixed tumors occurring simultaneously in major and minor salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363240"}
{"pmid": "4363245", "title": "Activation of the murine sarcoma virus genome after infection with the murine leukemia virus as determined by cell agglutination.", "content": "Activation of the murine sarcoma virus genome after infection with the murine leukemia virus as determined by cell agglutination. Non-virus-producing NIH/3T3 cells transformed by the murine sarcoma virus are agglutinated by conconavalin A to the same low level as normal NIH/3T3 cells. Infection with the murine leukemia virus greatly increases the agglutination of transformed cells but not that of normal cells. These data suggest that the morphological expression of cell transformation and the surface alterations associated with increased cell agglutination are controlled by the expressions of different sarcoma virus genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363245"}
{"pmid": "4363237", "title": "Pseudomonas infections of skin: an experimental study.", "content": "Pseudomonas infections of skin: an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363237"}
{"pmid": "4363244", "title": "Inability of adenosine 3':5'-cyclic monophosphate to simulate fully the effects of LH in rabbit ovaries.", "content": "Inability of adenosine 3':5'-cyclic monophosphate to simulate fully the effects of LH in rabbit ovaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363244"}
{"pmid": "4363246", "title": "Synthesis of avian oncornavirus DNA in infected chicken cells.", "content": "Synthesis of avian oncornavirus DNA in infected chicken cells. The intracellular synthesis and integration of viral DNA (vDNA) into the host cell genome was studied in cultured chicken embryo fibroblasts infected with avian sarcoma or leukemia viruses. The newly synthesized vDNA was detected by hybridization with 70S viral RNA. Extraction of infected cell DNA by the selective procedure of Hirt resulted in the enrichment of newly synthesized vDNA in the low molecular weight supernatant fraction while leaving the bulk of cellular DNA containing integrated vDNA in the high molecular weight pellet fraction. This approach led to detection of intracellular vDNA synthesis within 1 h after infection and to vDNA integration into cellular DNA within 24 h. There was a several-fold increase in the vDNA content of infected cells during the initial phase of virus infection. But only a part of this newly synthesized vDNA appeared to become covalently linked with high molecular weight cellular DNA. Most of the remaining unintegrated vDNA gradually disappeared. The sedimentation profiles of minimally sheared cellular DNA in alkaline sucrose velocity gradients suggest that vDNA is synthesized as free linear molecules of approximately 3 x 10(6) daltons which subsequently are covalently linked to host cell DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363246"}
{"pmid": "4363247", "title": "Comparison of two human papovaviruses with simian virus 40 by structural protein and antigenic analysis.", "content": "Comparison of two human papovaviruses with simian virus 40 by structural protein and antigenic analysis. The proteins of simian virus 40 (SV40) and two human papovaviruses, the hemagglutinating BK virus and the non-hemagglutinating DAR virus, were analyzed and compared by sodium dodecyl sulfate polyacrylamide gel electrophoresis. The virions of SV40 and DAR contain seven proteins. By molecular weight analysis the constituent proteins of SV40 and DAR are identical. Approximately 84% of the viral protein has a molceular weight of 45,000. The major protein of BK virus is 3,000 to 5,000 daltons lighter than the major proteins of SV40 and DAR viruses. The five most rapidly migrating proteins of BK virus are indistinguishable by molecular weight analysis from the corresponding proteins of SV40 and DAR viruses. Radial immunodiffusion and immunoelectrophoresis of whole virus gave lines of identity between SV40 and DAR when reacted with SV40 antibody. SV40 antiserum tested against BK virus and BK antiserum tested against SV40 virus showed no reactivity by complement fixation, immunodiffusion, or immunoelectrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363247"}
{"pmid": "4363248", "title": "Effect of ionic strength on the binding of Sindbis virus to chick cells.", "content": "Effect of ionic strength on the binding of Sindbis virus to chick cells. Sindbis virus can adsorb to chicken embryo fibroblasts in two different ways. \"Loosely\" bound virus can be washed off the cell with buffers of ionic strength 0.2 or greater, whereas \"tightly\" bound virus remains attached under these conditions. When Sindbis virus is adsorbed to chick cells at 4 C from a buffer of ionic strength 0.17, 40 to 50% of the adsorbed virus is loosely bound, the remainder tightly bound. Infection of chick cells by Sindbis virus has only small effects on the total amount of virus that can be bound to the cells. However, the amount of Sindbis virus that can be tightly bound declines rapidly beginning at 2 to 3 h after infection. By 7 h after infection, the amount of virus that can be tightly bound is only 10 to 20% of the amount bound to uninfected cells. The adsorption (and penetration) of virus at 37 C is most efficient at an ionic strength of 0.15 to 0.17; at this ionic strength most of the adsorbed virus is tightly bound. At higher ionic strengths the virus adsorbs poorly. At lower ionic strengths most of the virus is loosely bound. A second enveloped virus, vesicular stomatitis virus, has been studied for the purposes of comparison; its adsorption behavior differs from that of Sindbis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363248"}
{"pmid": "4363249", "title": "Analysis of a viral agent isolated from multiple sclerosis brain tissue: characterization as a parainfluenzavirus type 1.", "content": "Analysis of a viral agent isolated from multiple sclerosis brain tissue: characterization as a parainfluenzavirus type 1. A virus originally isolated from cell cultures obtained by lysolecithin-induced fusion of human multiple sclerosis brain cells with CV-1 cells has been analyzed for its antigenic, RNA, and polypeptide compositions, and for selective biological properties. Our findings establish that this isolate, designated 6/94 virus, contains a 50S RNA genome and is, as yet, indistinguishable from Sendai virus in its antigenic and total polypeptide compositions. Despite these similarities, the 6/94 and Sendai viruses differ in certain phenotypic properties. 6/94 virus is markedly less cytocidal for chick fibroblasts, especially at 37 C and, after beta-propiolactone inactivation, it possesses a greater capacity for cell fusion and a lower toxicity than does comparably treated Sendai virus. In addition, 6/94 virus shows greater hemolytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363249"}
{"pmid": "4363250", "title": "Location of the origin of DNA replication in adenovirus Type 2.", "content": "Location of the origin of DNA replication in adenovirus Type 2. Utilizing the isolated left and right halves of both adenovirus type 2 and the nondefective adenovirus simian virus 40 hybrid (Ad2(+)ND(1)), studies were undertaken to find the site on the DNA molecules at which replication begins. The data are consistent with several models which include an initiation event at both ends and bidirectional growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363250"}
{"pmid": "4363251", "title": "Polyadenylation of vesicular stomatitis virus mRNA.", "content": "Polyadenylation of vesicular stomatitis virus mRNA. Vesicular stomatitis virus (VSV) mRNA isolated from infected cell polysomes contains polyadenylic acid [poly(A)] sequences. Detergent-activated purified virions in vitro can transcribe complementary RNA, which has sedimentation properties similar to mRNA, and this RNA also contains poly(A) sequences. Digestion of virion RNA with U2 RNase under conditions where hydrolysis is specific for purine linkages leaves no sequences of polyuridylic acid corresponding in length to the poly(A) on the transcripts. Growth of infectious virus is not inhibited by 3-deoxyadenosine (cordycepin) under conditions in which it inhibits polyadenylation of cellular mRNA. The virus-specific mRNA produced in the presence of cordycepin has poly(A) sequences of the same size distribution as that synthesized in the absence of cordycepin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363251"}
{"pmid": "4363253", "title": "Complementation analysis of simian virus 40 mutants.", "content": "Complementation analysis of simian virus 40 mutants. Seventy six new temperature-sensitive mutants of simian virus 40 have been isolated. A simple modification of the standard plaquing technique permits complementation analyses to be performed readily. By using this technique the new mutants have been divided into four complementation groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363253"}
{"pmid": "4363252", "title": "Poliovirus infection and poly(A) sequences of cytoplasmic cellular RNA.", "content": "Poliovirus infection and poly(A) sequences of cytoplasmic cellular RNA. The influence of polio infection on Poly(A) sequences of cellular cytoplasmic RNA was investigated. In the presence of guanidine, cellular protein synthesis was still shut off after poliovirus infection, although there was no viral RNA synthesis. The Poly(A) of these cells was unchanged with respect to quantity, size, and linkage to cellular cytoplasmic RNA. This finding strongly suggests that the shut off of cellular protein synthesis is not caused by a change of the Poly(A) sequences of cellular mRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363252"}
{"pmid": "4363254", "title": "Separation of B and C type virions by centrifugation in gentle density gradients.", "content": "Separation of B and C type virions by centrifugation in gentle density gradients. Murine type B particles were separated from type C (Rauscher leukemia virus) by means of gentle (low-increment rate) density gradients. The best separation was obtained when the density ranged from 1.13 to 1.20 g/cm(3) when sucrose was used and from 1.12 to 1.28 g/cm(3) with CsCl. The buoyant densities of the B and C particle bands in sucrose were 1.18 and 1.16 g/cm(3), respectively. The CsCl gradient gave a better separation with the B particles banding at a density of 1.20 g/cm(3) and with the C particle density little different from its value in sucrose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363254"}
{"pmid": "4363255", "title": "Isolation and partial characterization of different defective DNA molecules derived from polyoma virus.", "content": "Isolation and partial characterization of different defective DNA molecules derived from polyoma virus. Supercoiled DNA molecules purified from mouse cells infected with high-multiplicity-passaged polyoma virus has a broader size distribution and sediments more slowly than DNA derived from low-multiplicity-passaged virus. The shorter DNA molecules are predominately noninfectious. Virus populations containing distinct size classes of defective virus DNA were isolated by growing virus from single cells infected by a defective and nondefective helper virus (infectious center). This technique probably results in the cloning of defective virus particles. By applying the infectious center method to DNA from various fractions of sucrose gradients it has been possible to obtain shorter circular DNA molecules ranging in size from 50 to 95% of the unit-length polyoma DNA molecule. The shorter molecules in any one preparation are homogeneous in size. This class size is retained upon repeated passage of crude viral lysates at high multiplicity. Thus far, all the purified shorter DNA molecules tested appear to be noninfectious and largely resistant to cleavage by the R(1) restriction enzyme. Some of the purified defective molecules have been found to interfere with the production of infectious virus upon co-infection with unit-length infectious polyoma DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363255"}
{"pmid": "4363256", "title": "Surface membrane glycopeptides which coincide with virus transformation and tumorigenesis.", "content": "Surface membrane glycopeptides which coincide with virus transformation and tumorigenesis. Glycopeptides from the surface of clones of hamster embryo cells were examined at various intervals after infection with polyoma virus. Two types of transformed cells were examined: (i) clones that showed delayed transformation or an initially low tumorigenicity, and (ii) clones that were rapidly transformed showing an initially high tumorigenicity. The glycopeptides were removed from the cell surface by trypsin and, after Pronase digestion, were examined by filtration through Sephadex G-50. With delayed transformation, a specific group of glycopeptides was increasingly evident over an 85-day period as the cells showed phenotypic properties of transformation and the ability to form tumors. In the other series, all but one clone of hamster embryo cells showed rapid transformation after infection with polyoma virus. This clone was less tumorigenic and showed little of the specific glycopeptides. In all cases of delayed or rapid transformation examined, the specific group of glycopeptides increased proportionately to the ability of the cells to form tumors. All of the cells derived from progressively growing tumors formed by injection of these transformed hamster cells into adult animals showed an abundance of this group of glycopeptides. These results suggest that specific surface membrane glycopeptides accompany viral transformation and tumorigenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363256"}
{"pmid": "4363283", "title": "Toward control of tumour and virus growth by helical RNA. II. Difference in the post-integrational control of virus synthesis by Poly I:C in acutely and chronically B77 virus infected cells.", "content": "Toward control of tumour and virus growth by helical RNA. II. Difference in the post-integrational control of virus synthesis by Poly I:C in acutely and chronically B77 virus infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363283"}
{"pmid": "4363284", "title": "Possiblity of cancer diagnosis by detection of Clostridial antibodies.", "content": "Possiblity of cancer diagnosis by detection of Clostridial antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363284"}
{"pmid": "4363285", "title": "Lesions in sheep skeletal and oesophageal muscle in vermeersiekte (Geigeria ornativa O. Hoffm. poisoning).", "content": "Lesions in sheep skeletal and oesophageal muscle in vermeersiekte (Geigeria ornativa O. Hoffm. poisoning).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363285"}
{"pmid": "4363286", "title": "Congenital mesoblastic nephroma of infancy.", "content": "Congenital mesoblastic nephroma of infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363286"}
{"pmid": "4363290", "title": "Cell surface receptors--structure and function.", "content": "Cell surface receptors--structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363290"}
{"pmid": "4363291", "title": "Platelet function in health and disease.", "content": "Platelet function in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363291"}
{"pmid": "4363292", "title": "Origin and formation of lymph lipids in the sheep.", "content": "Origin and formation of lymph lipids in the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363292"}
{"pmid": "4363294", "title": "Amniogenic bands as a cause of syndactyly in a young human fetus.", "content": "Amniogenic bands as a cause of syndactyly in a young human fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363294"}
{"pmid": "4363293", "title": "Calcification of oral bacteria: an ultrastructural study of two strains of Bacterionema matruchotii.", "content": "Calcification of oral bacteria: an ultrastructural study of two strains of Bacterionema matruchotii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363293"}
{"pmid": "4363304", "title": "A note on fine structure of synovial sarcoma.", "content": "A note on fine structure of synovial sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363304"}
{"pmid": "4363303", "title": "An autopsy case of primary cytomegalic inclusion enteritis with remarkable hypoproteinemia.", "content": "An autopsy case of primary cytomegalic inclusion enteritis with remarkable hypoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363303"}
{"pmid": "4363305", "title": "Studies on animal collagenase.", "content": "Studies on animal collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363305"}
{"pmid": "4363306", "title": "On the turnover of acetylcholine in the brain. An experimental study using intravenously injected radioactive choline.", "content": "On the turnover of acetylcholine in the brain. An experimental study using intravenously injected radioactive choline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363306"}
{"pmid": "4363302", "title": "Mucous substance and enzyme histochemistry of non-neoplastic and neoplastic gastric epithelium in man.", "content": "Mucous substance and enzyme histochemistry of non-neoplastic and neoplastic gastric epithelium in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363302"}
{"pmid": "4363318", "title": "Some current concepts and concerns relative to amebae and disease in man.", "content": "Some current concepts and concerns relative to amebae and disease in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363318"}
{"pmid": "4363325", "title": "Virulence of axenically cultivated E. histolytica.", "content": "Virulence of axenically cultivated E. histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363325"}
{"pmid": "4363326", "title": "Studies on antibody surveillance to EB virus-induced antigen in patients with sarcoidosis and nasopharyngeal carcinoma by indirect immunofluorescence.", "content": "Studies on antibody surveillance to EB virus-induced antigen in patients with sarcoidosis and nasopharyngeal carcinoma by indirect immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363326"}
{"pmid": "4363327", "title": "Aberrant forms of varicella-zoster virus.", "content": "Aberrant forms of varicella-zoster virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363327"}
{"pmid": "4363328", "title": "Control of flagellum formation in Naegleria gruberi.", "content": "Control of flagellum formation in Naegleria gruberi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363328"}
{"pmid": "4363333", "title": "Metabolic pathways and control mechanisms involved in the biosynthesis and turnover of collagen in normal and pathological connective tissues.", "content": "Metabolic pathways and control mechanisms involved in the biosynthesis and turnover of collagen in normal and pathological connective tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363333"}
{"pmid": "4363334", "title": "Electron optic analysis of human dentin in hypophosphatemic vitamin D-resistant rickets (report of a kindred with consanguinity).", "content": "Electron optic analysis of human dentin in hypophosphatemic vitamin D-resistant rickets (report of a kindred with consanguinity).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363334"}
{"pmid": "4363335", "title": "Collagen metabolism in pericoronitis.", "content": "Collagen metabolism in pericoronitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363335"}
{"pmid": "4363329", "title": "Electron-phonon (trapped photon) coupling and infrared coaxial transmission line theory of energy transport in mitochondria and nerve.", "content": "Electron-phonon (trapped photon) coupling and infrared coaxial transmission line theory of energy transport in mitochondria and nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363329"}
{"pmid": "4363341", "title": "Current therapy approaches of the Division of Cancer Treatment with emphasis on pancreatic carcinoma.", "content": "Current therapy approaches of the Division of Cancer Treatment with emphasis on pancreatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363341"}
{"pmid": "4363343", "title": "A study of the mechanism of the formation of the unproductive lactate dehydrogenase-NAD-pyruvate ternary complex.", "content": "A study of the mechanism of the formation of the unproductive lactate dehydrogenase-NAD-pyruvate ternary complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363343"}
{"pmid": "4363345", "title": "Fine structure of the magnetooptical rotatory dispersion curves and the surroundings of heme in ferrocytochrome c and its model compounds.", "content": "Fine structure of the magnetooptical rotatory dispersion curves and the surroundings of heme in ferrocytochrome c and its model compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363345"}
{"pmid": "4363344", "title": "Conformational analysis of globular proteins by optical rotatory dispersion.", "content": "Conformational analysis of globular proteins by optical rotatory dispersion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363344"}
{"pmid": "4363340", "title": "Proceedings: 155. Role of brain biogenic amines in the regulation of ACTH secretion in the rat.", "content": "Proceedings: 155. Role of brain biogenic amines in the regulation of ACTH secretion in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363340"}
{"pmid": "4363347", "title": "In vitro studies on the nature of prostaglandin E1 binding in the hamster uterus.", "content": "In vitro studies on the nature of prostaglandin E1 binding in the hamster uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363347"}
{"pmid": "4363350", "title": "Proceedings: A new rapid method of enzymic analysis using rate reaction techniques.", "content": "Proceedings: A new rapid method of enzymic analysis using rate reaction techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363350"}
{"pmid": "4363356", "title": "Inhibition of 3',5'-cyclic AMP phosphodiesterase by acid mucopolysaccharides and sulfopolysaccharides.", "content": "Inhibition of 3',5'-cyclic AMP phosphodiesterase by acid mucopolysaccharides and sulfopolysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363356"}
{"pmid": "4363357", "title": "Inhibition of 3',5'-cyclic AMP phosphodiesterase with anti-inflammatory agents.", "content": "Inhibition of 3',5'-cyclic AMP phosphodiesterase with anti-inflammatory agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363357"}
{"pmid": "4363358", "title": "Enhancement of the hepatotoxicity of trichloroethylene by inducers of drug metabolism.", "content": "Enhancement of the hepatotoxicity of trichloroethylene by inducers of drug metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363358"}
{"pmid": "4363359", "title": "The effect of apyrase on platelet retention in normal subjects and in patients with abnormal cardiac valves or with von Willebrand's disease.", "content": "The effect of apyrase on platelet retention in normal subjects and in patients with abnormal cardiac valves or with von Willebrand's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363359"}
{"pmid": "4363361", "title": "Effects of prostaglandins E1 and E2 on renal sodium reabsorption and Starling forces.", "content": "Effects of prostaglandins E1 and E2 on renal sodium reabsorption and Starling forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363361"}
{"pmid": "4363360", "title": "Experimental observations on the effects of physical training upon intrinsic cardiac physiology and biochemistry.", "content": "Experimental observations on the effects of physical training upon intrinsic cardiac physiology and biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363360"}
{"pmid": "4363362", "title": "Fever produced in the squirrel monkey by intravenous and intracerebral endotoxin.", "content": "Fever produced in the squirrel monkey by intravenous and intracerebral endotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363362"}
{"pmid": "4363363", "title": "Brush-border processes and transepithelial Na and Cl transport by rabbit ileum.", "content": "Brush-border processes and transepithelial Na and Cl transport by rabbit ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363363"}
{"pmid": "4363364", "title": "Effects of ADH and other agents on cyclic AMP accumulation in toad bladder epithelium.", "content": "Effects of ADH and other agents on cyclic AMP accumulation in toad bladder epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363364"}
{"pmid": "4363365", "title": "Effects of hormones on cyclic AMP formation in kidneys of nonmammalian vertebrates.", "content": "Effects of hormones on cyclic AMP formation in kidneys of nonmammalian vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363365"}
{"pmid": "4363366", "title": "Dibutyryl cyclic AMP and potassium transport in cardiac Purkinje fibers.", "content": "Dibutyryl cyclic AMP and potassium transport in cardiac Purkinje fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363366"}
{"pmid": "4363368", "title": "Enumeration of food-borne Clostridium perfringens in egg yolk-free tryptose-sulfite-cycloserine agar.", "content": "Enumeration of food-borne Clostridium perfringens in egg yolk-free tryptose-sulfite-cycloserine agar. The SFP (Shahidi-Ferguson perfringens), TSC (tryptose-sulfite-cycloserine), EY (egg yolk)-free TSC, and OPSP (oleandomycin-polymyxin-sulfadiazine perfringens) agars have been tested for their suitability to enumerate Clostridium perfringens in naturally contaminated foods. Complete recoveries of C. perfringens were obtained in each of the four media, but only the TSC and EY-free TSC agars were sufficiently selective to ensure subsequent confirmatory tests without interference from facultative anaerobes. Because of some disadvantages associated with the use of egg yolk, EY-free TSC agar is recommended for enumeration of C. perfringens in foods. Several conditions for convenient shipment of foods and C. perfringens isolates with minimum loss of viability have been tested. The highest viable counts were preserved when foods were mixed 1:1 (wt/vol) with 20% glycerol and kept in a container with dry ice. Isolated C. perfringens strains remained viable for at least 2 weeks at ambient temperatures on blood agar slopes with a 2% agar overlay in screw-cap culture tubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363368"}
{"pmid": "4363367", "title": "Recovery of poliovirus from turbid estuarine water on microporous filters by the use of celite.", "content": "Recovery of poliovirus from turbid estuarine water on microporous filters by the use of celite. The application of a new step for recovering poliovirus from moderately to highly turbid estuarine water by the filter virus-adsorption technique was investigated. The experiments were conducted under both (i) laboratory-based conditions (200-ml volumes) where the turbidity was controlled and (ii) simulated field conditions (15- to 100-gal volumes) where the turbidity varied depending upon the hydrology of the raw estuarine water. The new step consisted of adding Celite to the turbid water prior to sampling for virus. In the experiments, the pH of the water was first adjusted to 3.5 and then AlCl(3) was added to 0.0005 M. Celite was added to a concentration of 0.01% and mixed thoroughly. Either an HE Cox M-780 microfilter (Cox Instrument, Div. of Lynch Corp., Detroit, Mich.) or an MF-membrane filter (Millipore Corp., Bedford, Mass.) was used as the virus adsorbent. Virus was eluted from the Celite-filter complex in situ at pH 9 with 5x nutrient broth. In the laboratory-based experiments, when turbidity ranged from 5.0 to 30.0 Jackson turbidity units (JTU), virus recovery ranged from 66 to 89%. In the simulated field experiments, when the turbidity ranged from 8.5 to 80.0 JTU, virus recovery ranged from <1 to 74%, depending upon the multiplicity of virus input and the level of turbidity. The new step greatly improved the filtration-flux of turbid water and significantly reduced the premature clogging problem usually observed with microporous filters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363367"}
{"pmid": "4363370", "title": "The amino acid sequence of a protein (apovitellenin I) from the low-density lipoprotein of emu egg yolk.", "content": "The amino acid sequence of a protein (apovitellenin I) from the low-density lipoprotein of emu egg yolk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363370"}
{"pmid": "4363369", "title": "Enumeration of fecal Clostridium perfringens spores in egg yolk-free tryptose-sulfite-cycloserine agar.", "content": "Enumeration of fecal Clostridium perfringens spores in egg yolk-free tryptose-sulfite-cycloserine agar. The Shahidi-Ferguson perfringens, tryptose-sulfite-cycloserine (TSC), and egg yolk-free TSC agars have been tested for their suitability to enumerate fecal spores of Clostridium perfringens. When these spores comprised at least 20% of the total anaerobe spores, equally accurate counts were obtained in the three media. With lower ratios of C. perfringens spores, the most accurate counts were obtained in egg yolk-free TSC agar. The median C. perfringens spore count of 60 normal fecal specimens was log 3.4/g. A nonmotile, sulfite- and nitrate-reducing Clostridium, not identifiable with any known clostridial species, was isolated from 14 out of 60 fecal specimans. It was not differentiated from C. perfringens in the nitrite motility test, but could be distinguished by its inability to liquefy gelatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363369"}
{"pmid": "4363373", "title": "Editorial: The heart during sleep.", "content": "Editorial: The heart during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363373"}
{"pmid": "4363374", "title": "Pathology of murine cytomegalovirus infection in newborn mice. Muscle, heart, and brown fat lesions.", "content": "Pathology of murine cytomegalovirus infection in newborn mice. Muscle, heart, and brown fat lesions. Newborn mice were inoculated intracerebrally with murine cytomegalovirus and studies were made of the pathological changes in the striate and cardiac muscle and brown fat. Widespread necrosis was seen in muscle and brown fat in the early stages of the infection. Necrotic lesions became calcified. By 56 days lesions were not resolved in the heart and brown fat but were completely resolved in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363374"}
{"pmid": "4363375", "title": "Clinical pharmacology as an approach to the study of biochemical sleep mechanisms: the action of L-dopa.", "content": "Clinical pharmacology as an approach to the study of biochemical sleep mechanisms: the action of L-dopa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363375"}
{"pmid": "4363376", "title": "Retarded growth of rats by anticonvulsant drugs.", "content": "Retarded growth of rats by anticonvulsant drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363376"}
{"pmid": "4363377", "title": "The polycyclic sleep-wake cycle in the cat: effects produced by sensorimotor rhythm conditioning.", "content": "The polycyclic sleep-wake cycle in the cat: effects produced by sensorimotor rhythm conditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363377"}
{"pmid": "4363378", "title": "Asymptomatic infection with EB virus.", "content": "Asymptomatic infection with EB virus. Evidence of asymptomatic EB virus infection was sought in healthy medical students and nurses following the observation that 1.4% possessed heterophile antibodies. The proportion of subjects with EB virus antibodies rose with age and there was evidence of recent infection in 19%. Smooth muscle antibodies were detected in 13 individuals and recent infection with EB virus was probable in six of these. Subclinical EB virus infections, in some cases associated with some disturbance of immunological function, may therefore be not uncommon in young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363378"}
{"pmid": "4363380", "title": "A cyclic adenosine monophosphate link in the catecholamine enhancement of transmitter release at the neuromuscular junction.", "content": "A cyclic adenosine monophosphate link in the catecholamine enhancement of transmitter release at the neuromuscular junction. The frequency of miniature endplate potentials (mepps) in rat diaphragms was markedly increased by epinephrine and norepinephrine in preparations exposed to 15 mM K(+). The effect was rapid in onset but gradually declined during continued exposure to the catecholamines. N(6), O(2')-dibutyryl adenosine 3',5'-monophosphate (dibutyryl-cAMP) also caused transient frequency increases resembling in time-course those observed with catecholamines. Contrary to previous reports, catecholamines and dibutyryl-cAMP had little effect on mepp frequency in preparations not treated with K(+). Sustained increases with theophylline and decreases with adenosine were found in both K(+)-treated and untreated preparations. Analysis of the data obtained with catecholamines showed the intensity of the response to be a function of nerve terminal polarization. The inability of catecholamines and dibutyryl-cAMP to affect mepp frequency of untreated preparations argues against an obligatory role for cAMP in the neurosecretory mechanism. The findings are consistent with an action of catecholamines and cAMP in the regulation of transmitter release at fatigued preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363380"}
{"pmid": "4363382", "title": "Metabolic effects of antibodies on platelets.", "content": "Metabolic effects of antibodies on platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363382"}
{"pmid": "4363383", "title": "Pulmonary generation and peripheral uptake of endogenous angiotensin II in man.", "content": "Pulmonary generation and peripheral uptake of endogenous angiotensin II in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363383"}
{"pmid": "4363385", "title": "Stimulation of adenosine 3',5'-cyclic monophosphate accumulation in anterior pituitary gland in vitro by purified growth hormone-releasing hormone.", "content": "Stimulation of adenosine 3',5'-cyclic monophosphate accumulation in anterior pituitary gland in vitro by purified growth hormone-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363385"}
{"pmid": "4363379", "title": "Investigation of the accompaniment of calcium during active calcium transport from human erythrocyte ghosts.", "content": "Investigation of the accompaniment of calcium during active calcium transport from human erythrocyte ghosts. To determine whether a cell metabolite was involved in active calcium transport, the cell contents of human erythrocytes were subjected to high dilutions and the resultant ghosts were checked for their ability to actively transport calcium. It was found that the diluted erythrocyte ghosts did retain their capacity to actively transport calcium and that the characteristics of this transport process appeared to be unaltered by the high dilutions. Calcium analysis of the cell membrane and cell supernatant indicated that almost all of the calcium was lost from the cell solution rather than the cell membrane as active calcium transport proceeded. Therefore it appeared that calcium was able to cross the cell membrane without the aid of a cell metabolite. Investigations with layered erythrocytes indicated that the active transport of calcium was not assisted by centrifugation. Neither inorganic phosphate, pyrophosphate, nor an adenine nucleotide appeared to accompany calcium across the membrane as indicated by total phosphate and inorganic phosphate analysis and 260-nm readings of the deproteinized supernatant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363379"}
{"pmid": "4363384", "title": "Evidence that acromegaly is not a hypothalamic disease.", "content": "Evidence that acromegaly is not a hypothalamic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363384"}
{"pmid": "4363386", "title": "In vitro demonstration of normal thyrotropin (TSH) responsiveness in thyroid tissue from patients with Graves' disease.", "content": "In vitro demonstration of normal thyrotropin (TSH) responsiveness in thyroid tissue from patients with Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363386"}
{"pmid": "4363387", "title": "Antifracture efficacy of long-term estrogens for osteoporosis.", "content": "Antifracture efficacy of long-term estrogens for osteoporosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363387"}
{"pmid": "4363388", "title": "The Distinguished Lecture. The adrenal cortex: reflections, progress and speculations.", "content": "The Distinguished Lecture. The adrenal cortex: reflections, progress and speculations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363388"}
{"pmid": "4363389", "title": "Cartilage collagen: substrate in soluble and fibrillar form for rheumatoid collagenase.", "content": "Cartilage collagen: substrate in soluble and fibrillar form for rheumatoid collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363389"}
{"pmid": "4363392", "title": "Development of chloroplasts in intact Atropa belladonna and in stem callus cultures during greening and leaf differentiation.", "content": "Development of chloroplasts in intact Atropa belladonna and in stem callus cultures during greening and leaf differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363392"}
{"pmid": "4363393", "title": "Paneth cell metaplasia in diseases of the colon and rectum.", "content": "Paneth cell metaplasia in diseases of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363393"}
{"pmid": "4363394", "title": "Quantitative cytologic measurements in hepatomas.", "content": "Quantitative cytologic measurements in hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363394"}
{"pmid": "4363395", "title": "Complement-fixing antibodies against cytomegalovirus in different parts of the world.", "content": "Complement-fixing antibodies against cytomegalovirus in different parts of the world. A WHO cooperative study in which 27 laboratories participated showed that the distribution of cytomegalovirus antibodies in healthy blood donors varies widely, ranging from 40% in highly industrialized areas to 100% in developing countries. Climatic factors did not appear to play an important role in the spread of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363395"}
{"pmid": "4363396", "title": "Ecological studies on Culex tritaeniorhynchus as a vector of Japanese encephalitis.", "content": "Ecological studies on Culex tritaeniorhynchus as a vector of Japanese encephalitis. In the Republic of Korea, light-trap assessments and collections from cows and pigs after sunset were highly successful in monitoring the seasonal abundance of C. tritaeniorhynchus, the primary vector of Japanese encephalitis. The dates and duration of the population peaks at semirural suburbs of Seoul and Pusan were markedly different from those at a rural rice-growing site. The main breeding sites in these three areas were, respectively, swamps, marshes, and ricefields. The overall adult densities were the lowest at the rice-growing site where agricultural pesticides were extensively used. A short period of man-vector contact occurred at each study site at low densities when the natural population was at its peak. These vector monitoring techniques, coupled with information on antibodies in swine, represent a simple but valuable surveillance system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363396"}
{"pmid": "4363397", "title": "Immunity to cancer. Naturally occurring tumours in domestic animals as models for research. 1.", "content": "Immunity to cancer. Naturally occurring tumours in domestic animals as models for research. 1. PREVENTIVE VACCINATION IS SUCCESSFULLY PRACTISED TODAY AGAINST TWO NEOPLASTIC DISEASES OF DOMESTIC ANIMALS: fibropapillomatosis of cattle and Marek's disease of chickens (a lymphoproliferative disease). Also it may soon be possible to immunize cats against lymphosarcoma. This memorandum describes these diseases and the immunological reactions involved. It also mentions a number of other tumours that could be used for immunological studies.The greatest advances in immunity have been made with the tumours caused by viruses. The killed papillomavirus vaccine used against bovine papillomatosis produces demonstrable antibodies against the virus. In the case of Marek's disease of chickens, which is due to a herpesvirus, a live virus vaccine is used. This does not prevent infection with virulent virus, but prevents the development of neoplasia. The mechanism by which the vaccine produces its effect is not yet known. Immunization with live and with killed vaccines has been successfully carried out experimentally against leukosis of chickens, which is caused by an oncornavirus. There is evidence that it will be possible to vaccinate cats against lymphosarcoma with non-living vaccine.Naturally occurring cancer in domestic animals parallels cancer in man more closely than does experimentally induced cancer in inbred laboratory animals; therefore immunological studies with the former are more likely to yield results relevant to the problem in man. Experimental cancer in rodents provides models that have the great advantages of uniformity and availability, and they cannot be replaced. However, models in domestic animals offer valuable supplementary systems for research aimed at elucidating the basic principles of immunity to cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363397"}
{"pmid": "4363398", "title": "Limitations of immunofluorescence tests in the diagnosis of infectious mononucleosis.", "content": "Limitations of immunofluorescence tests in the diagnosis of infectious mononucleosis. The relative value of heterophil agglutinins (HA) and of specific EBV antibodies in the diagnosis of infectious mononucleosis (IM) was assessed in 108 cases of the disease and in 280 controls. Among the 108 cases 93 were HA-positive by sheep cells in at least one of their sera, while 15 were HA-negative by the same test. Among the 280 controls false-positive HA tests were not encountered except in eight cases with the horse cell microtitre tests. With one of the two slide tests at least two false-positive tests and 12 false-negative tests were also found but these sera had low titres in microtitre tests. The HA life-span was found to be unexpectedly long in a few cases, sheep cell HA lasting up to 8 to 10 months and horse cell HA up to 21 to 23 months.Many false-positive tests may therefore not be true false-positives and may result from the persistence of HA following unrecognized mononucleosis months before. Virtually all cases of IM had (or developed) antibodies to Epstein-Barr virus, viral capsid antigen (EBV-VCA), whereas only half of the controls were EBV-VCA-positive. The comparative analysis of nonspecific and specific test results in mononucleosis allows the following conclusions: (1) horse cell microtitre tests and the monospot test are more sensitive than sheep cell microtitre tests and the monotest; (2) false-negative results are occasionally seen with the latter tests but not with the former; (3) more false-positive results, however, are probably seen with the former tests; and (4) specific EBV-IgM and EBV-EA antibody tests are useful in the diagnosis of selected borderline cases of mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363398"}
{"pmid": "4363399", "title": "Parathyroid carcinoma: location of pelvic metastases by parathyroid hormone assay.", "content": "Parathyroid carcinoma: location of pelvic metastases by parathyroid hormone assay. A metastasis from a functioning parathyroid carcinoma was located by PTH radioimmunoassay and selective venous catheterization. The site of the metastasis, verified at autopsy, was in the right side of the pelvis. This is the most distant reported location for metastatic parathyroid carcinoma. The patient's plasma immunoreactive PTH rose more than twofold in response to induced hypocalcemia. This suggests that relative hypocalcemia, induced therapeutically in such patients, may result in a higher chronic level of PTH secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363399"}
{"pmid": "4363402", "title": "Address to Annual Meeting of the American Medical Women's Association.", "content": "Address to Annual Meeting of the American Medical Women's Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363402"}
{"pmid": "4363403", "title": "Success or failure: women as medical school applicants.", "content": "Success or failure: women as medical school applicants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363403"}
{"pmid": "4363404", "title": "Sex ratios in authorship and acknowledgments for medical journal articles.", "content": "Sex ratios in authorship and acknowledgments for medical journal articles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363404"}
{"pmid": "4363405", "title": "An internal auditing system for improving the quality of medical care.", "content": "An internal auditing system for improving the quality of medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363405"}
{"pmid": "4363406", "title": "Familial hypercholesterolemia (one form of familial type II hyperlipoproteinemia). A study of its biochemical, genetic and clinical presentation in childhood.", "content": "Familial hypercholesterolemia (one form of familial type II hyperlipoproteinemia). A study of its biochemical, genetic and clinical presentation in childhood. Primary hyperbetalipoproteinemia (type II hyperlipoproteinemia) is a common disorder associated with premature vascular disease. It is frequently due to genetic abnormalities, some of which are expressed in childhood. We have examined the manner in which that form of hyperbetalipoproteinemia known as familial hypercholesterolemia may be expressed in 236 children aged 1-19 born of 90 matings in which one parent had hyperbetalipoproteinemia of this variety and one parent did not.Two Gaussian populations were fitted to the distribution of both low density lipoprotein cholesterol (C(LDL)) and plasma cholesterol (C) in these children and a likelihood ratio test strongly favored a two over a one population model for both C(LDL) (X(2) = 18.41, P < 0.0005) and C (X(2) = 7.81, P < 0.025). 45% of the children were in the population identified as affected; their mean C(LDL) was 229. The remaining 55% were in the normal population with a mean C(LDL) of 110 which was indistinguishable from that of an unrelated control population, aged 1-19. On the basis of an assumed frequency of hyperbetalipoproteinemia in the general population of 5%, the Edwards' test indicated that a polygenic model of inheritance was highly unlikely (expected, 22%; observed, 45%). The segregation ratio obtained from the derived intersection between the two population curves (C(LDL), 164 mg/100 ml; C, 235 mg/100 ml) was 45/55 (abnormal/normal). The percentage of abnormal children in the first decade (52%) significantly exceeded that in the second (39%) (P < 0.01). The ratios (II/N) were 50/47 and 55/84 in the offspring of affected female and male parents, respectively (X(2) = 3.819, 0.05 < P < 0.10). Only 10% of hyperbetalipoproteinemic children were considered to have hyperglyceridemia. These children, frequently, but not invariably, had a parent with hyperglyceridemia in addition to hyperbetalipoproteinemia (P < 0.05). None of the affected children who were examined had ischemic heart disease (IHD) and 7% had tendon xanthomas. Half of the parents (mean age, 37.4 yr) who were examined had IHD and three-quarters had xanthomas. The data agree well with the hypothesis that hyperbetalipoproteinemia is inherited as a monogenic trait with early expression in these children. More than one genetic defect within the group is not excluded, but retrospective analyses of the 345 first-degree adult relatives of the affected parents indicated that most of the abnormal parents probably represented familial hypercholesterolemia, rather than combined hyperlipidemia, the other most generally recognized form of familial hyperbetalipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363406"}
{"pmid": "4363407", "title": "The effect of cyclic AMP and dibutyryl cyclic AMP on the permeability characteristics of the renal tubule.", "content": "The effect of cyclic AMP and dibutyryl cyclic AMP on the permeability characteristics of the renal tubule. The effect of adenosine-3',5'-cyclic monophosphate (cyclic AMP) and N(6),O(2)-dibutyryl adenosine-3',5'-cyclic monophosphate (dibutyryl cyclic AMP) on renal tubular permeability was studied by microinjection techniques in anesthetized diuretic rats. Radioactive inulin and mannitol were microinjected simultaneously into superficial proximal and distal convolutions and recovery of the isotopes was measured in the urine.During control conditions, mannitol and inulin recovery was essentially complete. However, during infusion of cyclic AMP or dibutyryl cyclic AMP, mannitol recovery was significantly less than control after early proximal and late proximal microinjections, averaging 79 and 85%, respectively. There was no loss of mannitol from the nephron after microinjection into distal convolutions. Inulin recovery was complete after all microinjections during cyclic AMP or dibutyryl cyclic AMP infusion. Simultaneous clearances of mannitol and inulin as well as peritubular capillary microinjections studies demonstrated bidirectional fluxes of mannitol across the proximal tubular epithelium during infusion of cyclic AMP or dibutyryl cyclic AMP. Intratubular pressures were not different during control and experimental periods. These studies demonstrate a change in the permeability characteristic of the proximal convoluted tubule during infusion of cyclic AMP and dibutyryl cyclic AMP. This change in permeability of the proximal tubule could account for the effects of cyclic AMP on proximal tubular transport processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363407"}
{"pmid": "4363408", "title": "Assay of total plasma apolipoprotein B concentration in human subjects.", "content": "Assay of total plasma apolipoprotein B concentration in human subjects. We have developed a double antibody radioimmunoassay (RIA) for human apolipoprotein B (ApoB). The assay measures not only the ApoB content of beta-lipoproteins (low density lipoproteins [LDL]) but also that contained in the other lipoproteins in plasma. Purified lymph and plasma chylomicrons and plasma very low density lipoproteins (VLDL) produced displacement curves in the assay system which paralleled those produced by pure LDL. Thus, the ApoB found in chylomicrons, VLDL, and LDL were immunologically identical. ApoB accounted for about 25 and 35%, respectively, of the total protein of chylomicrons and VLDL by RIA. VLDL and LDL preparations from normal and hyperlipoproteinemic subjects also produced parallel displacement curves, suggesting that the ApoB of normal and hyperlipoproteinemic subjects were immunologically identical. High density lipoproteins and abetalipoproteinemic plasma displaced no counts, nor did the sera of several animal species produce any useful displacement curves in this system. The fasting total plasma ApoB concentration of normal subjects was 83+/-16 mg/dl (mean+/-SD). ApoB levels were high in Type II (162+/-16), and less so in Type IV (112+/-24) and Type V (105+/-17).When plasma ApoB concentration in Type IV patients was graphed against plasma glycerides, two subpopulations, which may represent different genetic or biochemical subgroups, were apparent.ApoB concentration in individuals on constant diet and drug regimen was stable over weeks to months. Greater than 90% of ApoB of normal and Type II subjects was in the d > 1.006 plasma fraction. By contrast, only 50-80% of ApoB was in the d > 1.006 fraction in Types IV and V. Thus, hypertriglyceridemia was associated primarily with a redistribution of ApoB to the lighter density fractions; by contrast, in hypercholesterolemia absolute ApoB concentration was markedly increased.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363408"}
{"pmid": "4363409", "title": "Epstein-barr virus-negative human malignant T-cell lines.", "content": "Epstein-barr virus-negative human malignant T-cell lines. Two lymphoblastoid lines, CCRF-CEM and HSB-2, with properties of malignant cells, derived from children with leukemia secondary to lymphosarcoma, have T-cell properties and lack Epstein-Barr virus antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363409"}
{"pmid": "4363410", "title": "Concordant segregation of the expression of SV40 T antigen and human chromosome 7 in mouse-human hybrid subclones.", "content": "Concordant segregation of the expression of SV40 T antigen and human chromosome 7 in mouse-human hybrid subclones. Subcloning of Simian virus 40 (SV40) T antigen-positive mouse-human hybrids, derived from the fusion of mouse cells deficient in thymidine kinase with SV40-transformed Lesch Nyhan fibroblasts, resulted in their segregation into T antigen-positive and negative subclones. Positive correlation between the presence of human chromosome 7 and the expression of SV40 T antigen was established in the subclones examined. These results negate the possibility of a transfer of the SV40 genome to a mouse chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363410"}
{"pmid": "4363421", "title": "Aldosterone: current concepts.", "content": "Aldosterone: current concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363421"}
{"pmid": "4363424", "title": "Wilm's tumor: thirty-year review of cases in Buffalo.", "content": "Wilm's tumor: thirty-year review of cases in Buffalo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363424"}
{"pmid": "4363428", "title": "Increased production of cyclic AMP in mechanically stressed alveolar bone in cats.", "content": "Increased production of cyclic AMP in mechanically stressed alveolar bone in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363428"}
{"pmid": "4363429", "title": "Timing of interceptive orthodontic measures based on stages of maturation.", "content": "Timing of interceptive orthodontic measures based on stages of maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363429"}
{"pmid": "4363431", "title": "Hereditary deafness in the white cat.", "content": "Hereditary deafness in the white cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363431"}
{"pmid": "4363432", "title": "Immunoprecipitation is inappropriate for the isolation of radiochemically pure albumin from tissues.", "content": "Immunoprecipitation is inappropriate for the isolation of radiochemically pure albumin from tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363432"}
{"pmid": "4363433", "title": "A method for isolating respiring mitochondria from epiphyseal cartilage.", "content": "A method for isolating respiring mitochondria from epiphyseal cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363433"}
{"pmid": "4363434", "title": "A method for separating DNA fragments by electrophoresis in polyacrylamide concentration gradient slab gels.", "content": "A method for separating DNA fragments by electrophoresis in polyacrylamide concentration gradient slab gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363434"}
{"pmid": "4363435", "title": "Determination of 2,4-dihydroxy-1,4(2h)-benzoxazin-3-one glucosides in corn (Zea mays L.).", "content": "Determination of 2,4-dihydroxy-1,4(2h)-benzoxazin-3-one glucosides in corn (Zea mays L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363435"}
{"pmid": "4363436", "title": "Rapid sampling of yeast cells and automated assays of adenylate, citrate, pyruvate and glucose-6-phosphate pools.", "content": "Rapid sampling of yeast cells and automated assays of adenylate, citrate, pyruvate and glucose-6-phosphate pools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363436"}
{"pmid": "4363437", "title": "A high precision fluorometer for biochemical measurements.", "content": "A high precision fluorometer for biochemical measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363437"}
{"pmid": "4363439", "title": "Assay for the enzymic hydrolysis of penicillin and acylhydroxamates.", "content": "Assay for the enzymic hydrolysis of penicillin and acylhydroxamates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363439"}
{"pmid": "4363438", "title": "Adsorption chromatography of cyclic nucleotides on silica gel and alumina thin-layer sheets.", "content": "Adsorption chromatography of cyclic nucleotides on silica gel and alumina thin-layer sheets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363438"}
{"pmid": "4363440", "title": "Microanalytical determination of the activities of phospholipases A, C, and D and of their mixtures.", "content": "Microanalytical determination of the activities of phospholipases A, C, and D and of their mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363440"}
{"pmid": "4363442", "title": "Enzymatic synthesis of 32P-labeled coenzyme A.", "content": "Enzymatic synthesis of 32P-labeled coenzyme A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363442"}
{"pmid": "4363443", "title": "Percentage recovery of free fatty acids from bovine muscle lipids by nonchromatographic techniques.", "content": "Percentage recovery of free fatty acids from bovine muscle lipids by nonchromatographic techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363443"}
{"pmid": "4363441", "title": "Separation of proteins by high-speed pressure liquid chromatography.", "content": "Separation of proteins by high-speed pressure liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363441"}
{"pmid": "4363444", "title": "Antigenic structure of murine mammary tumour viruses.", "content": "Antigenic structure of murine mammary tumour viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363444"}
{"pmid": "4363445", "title": "The lack of effect of mouse epidermal growth factor (EGF) and its anti-serum on human tissues.", "content": "The lack of effect of mouse epidermal growth factor (EGF) and its anti-serum on human tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363445"}
{"pmid": "4363446", "title": "Carcinogenic effect of N-nitrosoamines related to butyl(4-hydroxybutyl)nitrosoamine in ACI-N rats, with special reference to induction of urinary bladder tumors.", "content": "Carcinogenic effect of N-nitrosoamines related to butyl(4-hydroxybutyl)nitrosoamine in ACI-N rats, with special reference to induction of urinary bladder tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363446"}
{"pmid": "4363447", "title": "Spin concentration per living cell of normal liver, regenerating liver, and hepatomas.", "content": "Spin concentration per living cell of normal liver, regenerating liver, and hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363447"}
{"pmid": "4363450", "title": "The evolution of a state hospital into a human-services center.", "content": "The evolution of a state hospital into a human-services center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363450"}
{"pmid": "4363451", "title": "The impact of a mental health center on admissions to a state hospital system.", "content": "The impact of a mental health center on admissions to a state hospital system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363451"}
{"pmid": "4363452", "title": "On the mechanism of thymine formation from thymine glycol by gamma-irradiation in aqueous system.", "content": "On the mechanism of thymine formation from thymine glycol by gamma-irradiation in aqueous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363452"}
{"pmid": "4363453", "title": "Ultrastructure of inclusion bodies in type II cells of lung, human and sub-simian.", "content": "Ultrastructure of inclusion bodies in type II cells of lung, human and sub-simian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363453"}
{"pmid": "4363454", "title": "The velocity of lymph flow in the canine thoracic duct.", "content": "The velocity of lymph flow in the canine thoracic duct. 1. The velocity and pattern of movement of lymph in the thoracic duct of anaesthetized and conscious dogs has been studied by observing the movement of droplets of ultrafluid lipiodol in the duct.2. The velocity of flow when anaesthetized varied from 0.1-2.0 cm/sec, to 5.0 cm/sec when conscious.3. The pattern of flow was affected by respiration and the cardiac cycle. Most movement occurred at the end of inspiration.4. The duct of five autopsy preparations was perfused with saline to assess the volume and velocity of flow produced by the level of pressure gradients previously observed in the duct. These studies show that the small gradients (2-5 mmHg) observed during life are more than sufficient to produce the normal volume and velocity of flow measured. The mean resistance of the duct was 0.5 mmHg/ml. min.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363454"}
{"pmid": "4363455", "title": "Analysis of the role of cyclic adenosine 3',5'-monophosphate in catecholamine release.", "content": "Analysis of the role of cyclic adenosine 3',5'-monophosphate in catecholamine release. 1. Cyclic adenosine 3',5'-monophosphate (cyclic AMP) levels and catecholamine release were measured in cat adrenal glands perfused in situ with Locke solution.2. Cyclic AMP was present in the medulla in an amount which represented approximately one fifth of that present in the cortex.3. Perfusion with acetylcholine (ACh) or nicotine increased cyclic AMP both in the intact adrenal and in the perfusate. The time course of the changes in tissue cyclic AMP during stimulation was out of phase with the time course of catecholamine release. Maximal increases in cyclic AMP were not manifest until after 8 min of exposure to the secretogogue, whereas maximal rates of secretion occurred during the first minute.4. Theophylline (0.5 mM) increased basal and stimulated adrenal cyclic AMP levels, but did not potentiate the secretory response to ACh or nicotine.5. Perfusion with cyclic AMP or its dibutyryl derivative (0.2-4 mM) failed to effect a consistent or significant increase in the rate of catecholamine release and was unable to potentiate the secretory response to a submaximal concentration of ACh or calcium.6. The results suggest that, unlike calcium, cyclic AMP is not a direct mediator of medullary secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363455"}
{"pmid": "4363456", "title": "Plasma renin and angiotensin II in conscious pregnant ewes and their lambs.", "content": "Plasma renin and angiotensin II in conscious pregnant ewes and their lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363456"}
{"pmid": "4363457", "title": "Negative feed-back regulation of noradrenaline release by nerve stimulation in the perfused cat's spleen: differences in potency of phenoxybenzamine in blocking the pre- and post-synaptic adrenergic receptors.", "content": "Negative feed-back regulation of noradrenaline release by nerve stimulation in the perfused cat's spleen: differences in potency of phenoxybenzamine in blocking the pre- and post-synaptic adrenergic receptors. 1. The effects of low concentrations of phenoxybenzamine (8.8 x 10(-10) to 2.9 x 10(-7)M) on responses and on noradrenaline overflow elicited by nerve stimulation were studied in the perfused cat's spleen.2. In the presence of 8.8 x 10(-10)M or 2.9 x 10(-9)M phenoxybenzamine there was a significant reduction in responses to nerve stimulation while the overflow of the transmitter did not increase at the two frequencies of stimulation employed: 5 and 30 Hz.3. In the presence of 2.9 x 10(-8)M or 2.9 x 10(-7)M phenoxybenzamine the responses to nerve stimulation were practically abolished and a significant increase in transmitter overflow was obtained at both frequencies of stimulation. The drug was more effective in increasing transmitter overflow at 5 Hz when compared with 30 Hz.4. The higher effectiveness of phenoxybenzamine in blocking the post-synaptic alpha-receptor when compared with the blockade of the presynaptic alpha-receptor that regulates transmitter release is compatible with the view that these two receptors are not identical.5. A second alternative for the difference in effectiveness of phenoxybenzamine is that both types of alpha receptors are identical, but the spare receptor capacity for the presynaptic adrenergic receptors is higher than that of the post-synaptic receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363457"}
{"pmid": "4363458", "title": "Gamma-aminobutyric acid and inhibition in the septal nuclei of the rat.", "content": "Gamma-aminobutyric acid and inhibition in the septal nuclei of the rat. 1. The electrophoretic application of gamma-aminobutyrate (GABA) and glycine to septal neurones inhibited their discharge, but the currents required to cause equivalent degrees of inhibition were always smaller for GABA than for glycine.2. The actions of GABA but not those of glycine were antagonized by bicuculline and not by strychnine and vice versa.3. The recurrent collateral inhibition of lateral septal neurones and the direct inhibition of medial cells evoked by stimulation of the fimbria were blocked by bicuculline but not by strychnine.4. The bursting patterns of discharge of laterally situated medial septal neurones was disrupted by bicuculline, but required a longer application of the drug than was needed to block the direct fimbrial inhibition. It is suggested that this disruption is due to diffusion of the drug to affect the inhibitory interneurones of the lateral septum.5. It is concluded that the inhibitory processes in the septum involve GABA as the synaptic transmitter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363458"}
{"pmid": "4363461", "title": "Cell fusion induced by pederine.", "content": "Cell fusion induced by pederine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363461"}
{"pmid": "4363463", "title": "Repeated partial endoscopic resections as treatment for two patients with inoperable tracheal tumours.", "content": "Repeated partial endoscopic resections as treatment for two patients with inoperable tracheal tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363463"}
{"pmid": "4363462", "title": "The preparation of single cell suspensions from liver and their use for the study of protein synthesis.", "content": "The preparation of single cell suspensions from liver and their use for the study of protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363462"}
{"pmid": "4363466", "title": "Prophylaxis of endemic goitre.", "content": "Prophylaxis of endemic goitre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363466"}
{"pmid": "4363467", "title": "Five years follow-up in the treatment of endemic goiter by iodized oil.", "content": "Five years follow-up in the treatment of endemic goiter by iodized oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363467"}
{"pmid": "4363468", "title": "Biochemical studies on endemic goiter glands before and one year after an injection of iodized oil.", "content": "Biochemical studies on endemic goiter glands before and one year after an injection of iodized oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363468"}
{"pmid": "4363469", "title": "Factors which may alter the epidemiology of endemic goiter.", "content": "Factors which may alter the epidemiology of endemic goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363469"}
{"pmid": "4363470", "title": "Gonadotropins and ovarian function.", "content": "Gonadotropins and ovarian function. The current knowledge of the influence of gonadotropins on ovarian function is reviewed based primarily on human data but supplemented with references to animal studies.  2 aspects of ovarian function are under the influence of gonadotropins--follicular growth and maturation and steroid synthesis and secretion.  Follicular stimulatin hormone (FSH) promotes the growth of more advanced follicles.  Recent evidence suggests that estrogens increase the capacity of the ovary to bind FSH.  There is evidence that estrogen is produced in the theca interna of the maturing follicle.  It seems likely that the ultrastructural, enzymatic, and secretory changes seen in the thecae result from stimulation by low tonic levels of plasma luteinizing hormone (LH) in combination with FSH.  At ovulation the surge of gonadotropins is triggered off by the ri sing estrogen output.  Graafian follicles respond to LH in vitro with increased synthesis of progesterone and lactic acid.  The capacity to lutenize spontaneously develops before ovulation and perhaps the oocyte inhibits this function.  The development of the human corpus luteum is summariezed and the pattern of progesterone production described.  LH and human chorionic gondtropin acutely stimulate steroid synthesis by binding to specific sites on luteal cell menbranes to increase the synthesis of cyclic AMP.  The corpus luteum of early pregnancy differs morphologically and functionally from that of the cycle, increasing progesterone production which remains high until the 11th or 12th week of pregnancy.  The cortical stroma of the human ovary is steroidogenic i n character but producing androstenedion.  The stroma's capacity for synthesis varies with the cycle stage.  Each cell type synthesizes its characteristic spectum of steroid products.  How appropriate enzymes become activated in the cell and thus produce these steroids is as yet unknown.  Gonadotropins only initiate this differentiation and subsequently enhance the activity of transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363470"}
{"pmid": "4363472", "title": "Direct effects of alcohol on in vivo and in vitro exocrine pancreatic secretion and metabolism.", "content": "Direct effects of alcohol on in vivo and in vitro exocrine pancreatic secretion and metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363472"}
{"pmid": "4363471", "title": "Clinical implications of monoclonal gammopathy in chronic liver disease.", "content": "Clinical implications of monoclonal gammopathy in chronic liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363471"}
{"pmid": "4363474", "title": "Bordetella pertussis serotypes in a whooping cough outbreak.", "content": "Bordetella pertussis serotypes in a whooping cough outbreak.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363474"}
{"pmid": "4363473", "title": "Cytomegalovirus and renal vein thrombosis in a newborn infant.", "content": "Cytomegalovirus and renal vein thrombosis in a newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363473"}
{"pmid": "4363476", "title": "Disseminated herpes with hepatoadrenal necrosis in an adult.", "content": "Disseminated herpes with hepatoadrenal necrosis in an adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363476"}
{"pmid": "4363478", "title": "Virus-induced diabetes mellitus. II. Relationship between beta cell damage and hyperglycemia in mice infected with encephalomyocarditis virus.", "content": "Virus-induced diabetes mellitus. II. Relationship between beta cell damage and hyperglycemia in mice infected with encephalomyocarditis virus. Infection of DBA 2 male mice with the M variant of encephalomyocarditis virus resulted in a diabetes-like syndrome. Histologic examination of the pancreas revealed damage to the beta cells with little involvement of the acinar cells. The severity of the hyperglycemia correlated closely with the degree of beta cell damage. By immunofluorescence, viral antigens could be detected in the beta cells during the first 10 days of the infection. In contrast to the response found in male DBA 2 mice, infection of DBA 2 female mice and male mice of several other strains resulted in little if any elevation of blood glucose concentration. Histologic examination of the pancreas of these animals revealed only minimal damage to the beta cells. It is concluded that differences in the severity of the hyperglycemia between DBA 2 males and females and among the different strains of male mice tested are directly related to the degree of beta cell damage produced by the viral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363478"}
{"pmid": "4363475", "title": "Metabolic defects of primary hyperuricemia and gout.", "content": "Metabolic defects of primary hyperuricemia and gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363475"}
{"pmid": "4363477", "title": "Neurotropic virus-host relationship alterations due to variation in viral genome as studied by electron microscopy.", "content": "Neurotropic virus-host relationship alterations due to variation in viral genome as studied by electron microscopy. A series of experiments has been described in which litters of suckling rats were inoculated either with wild-type reovirus type III or one of two of its temperature-sensitive (ts) mutants. While the wild-type virus produced an acute, fatal syndrome, the ts mutants were substantially less neurovirulent. Of the ts mutant-inoculated animals, a large percentage of the surviving (chronic) animals given ts mutant B showed an unobstructive hydrocephalus ex vacuo whereas chronic ts mutant C animals showed no visible nervous system disease. The ts mutants persisted within the central nervous system (CNS) for 6 to 8 weeks, after which they could not be detected either virologically, immunologically or morphologically. In another set of experiments, organized CNS explants were studied following infection with either measles virus or the neuroadapted Mantooth strain of SSPE virus, a variant of measles. Wild measles (Edmonston strain) exerted an acute destructive effect, but SSPE virus had a tendency to enter into coexistence with the tissue without destroying its organotypic nature. These relationships are somewhat reminiscent of the neuropathologic conditions caused by these two viruses in man. Since the reovirus type III ts mutants possess both genetic and morphologic defects and in many instances cause CNS conditions different from that induced by the wild-type virus, it has been proposed that a comparable situation may exist after measles and SSPE virus infection. SSPE virions of the strain studied were found to be defective in certain viral components which may have contributed to the lower neurovirulence and its entering into a chronic relationship with the CNS, in contrast to the acute destructive nature of measles infection. The findings are discussed in terms of relevance to other chronic CNS diseases, particularly multiple sclerosis, in which the possiblity exists that a mutant virus is operative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363477"}
{"pmid": "4363483", "title": "Selection and characterization of acriflavine-induced mutants of Candida albicans.", "content": "Selection and characterization of acriflavine-induced mutants of Candida albicans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363483"}
{"pmid": "4363484", "title": "Initial steps in the degradation of n-alkane-1-sulphonates by Pseudomonas.", "content": "Initial steps in the degradation of n-alkane-1-sulphonates by Pseudomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363484"}
{"pmid": "4363479", "title": "Pathology of colonic polyps as it relates to surgical management.", "content": "Pathology of colonic polyps as it relates to surgical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363479"}
{"pmid": "4363490", "title": "Subcellular fractionation of rat cerebellum: an electron microscopic and biochemical investigation. II. Resolution of morphologically characterised fractions.", "content": "Subcellular fractionation of rat cerebellum: an electron microscopic and biochemical investigation. II. Resolution of morphologically characterised fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363490"}
{"pmid": "4363485", "title": "Pathways of glycollate metabolism in the blue-green alga Anabaena cylindrica.", "content": "Pathways of glycollate metabolism in the blue-green alga Anabaena cylindrica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363485"}
{"pmid": "4363491", "title": "The effect of high doses of synthetic ACTH on rat brain.", "content": "The effect of high doses of synthetic ACTH on rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363491"}
{"pmid": "4363480", "title": "A comparison of the interlaboratory reproducibility of the Hansen radioimmunoassay for carcinoembryonic antigen.", "content": "A comparison of the interlaboratory reproducibility of the Hansen radioimmunoassay for carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363480"}
{"pmid": "4363492", "title": "Corticosterone binding to hippocampus: immediate and delayed influences of the absence of adrenal secretion.", "content": "Corticosterone binding to hippocampus: immediate and delayed influences of the absence of adrenal secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363492"}
{"pmid": "4363495", "title": "Action of angiotensin and analogues on the heart.", "content": "Action of angiotensin and analogues on the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363495"}
{"pmid": "4363493", "title": "Androgen-induced enhancement of vascular reactivity.", "content": "Androgen-induced enhancement of vascular reactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363493"}
{"pmid": "4363494", "title": "Role of the N-terminal amino acid for the biological activities of angiotensin and inhibitory analogues.", "content": "Role of the N-terminal amino acid for the biological activities of angiotensin and inhibitory analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363494"}
{"pmid": "4363497", "title": "Constancy and linearity of the metabolic clearance of adrenocorticotropin in dogs.", "content": "Constancy and linearity of the metabolic clearance of adrenocorticotropin in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363497"}
{"pmid": "4363481", "title": "The diagnosis of malignant neoplasms in infants and children.", "content": "The diagnosis of malignant neoplasms in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363481"}
{"pmid": "4363482", "title": "Catecholamine measurements in pheochromocytoma and neuroblastoma.", "content": "Catecholamine measurements in pheochromocytoma and neuroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363482"}
{"pmid": "4363496", "title": "The effect of replacement of potassium by cesium ions on neuromuscular blockade of the rat phrenic nerve--diaphragm preparation in vitro.", "content": "The effect of replacement of potassium by cesium ions on neuromuscular blockade of the rat phrenic nerve--diaphragm preparation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363496"}
{"pmid": "4363499", "title": "The insulin-glucose ration in children with islet cell tumors of the pancreas.", "content": "The insulin-glucose ration in children with islet cell tumors of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363499"}
{"pmid": "4363498", "title": "Renin activity by radioimmunoassay: the plasma incubation step.", "content": "Renin activity by radioimmunoassay: the plasma incubation step.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363498"}
{"pmid": "4363500", "title": "Germ cell tumors of the ovary: the role of pathology in diagnosis and management.", "content": "Germ cell tumors of the ovary: the role of pathology in diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363500"}
{"pmid": "4363501", "title": "Gestational trophoblastic neoplasia.", "content": "Gestational trophoblastic neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363501"}
{"pmid": "4363486", "title": "Editorial: The compensated polarized light microscope in clinical rheumatology.", "content": "Editorial: The compensated polarized light microscope in clinical rheumatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363486"}
{"pmid": "4363488", "title": "Proceedings: Lymphocyte tubuloreticular structures--disease activity correlation and sequential studies in systemic lupus erythematosus.", "content": "Proceedings: Lymphocyte tubuloreticular structures--disease activity correlation and sequential studies in systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363488"}
{"pmid": "4363487", "title": "IV. Joint erosion in rheumatoid arthritis.", "content": "IV. Joint erosion in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363487"}
{"pmid": "4363504", "title": "Biochemistry of iron.", "content": "Biochemistry of iron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363504"}
{"pmid": "4363505", "title": "Intracellular recording of spontaneous local responses in the chronic epileptogenic focus of a rhesus monkey.", "content": "Intracellular recording of spontaneous local responses in the chronic epileptogenic focus of a rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363505"}
{"pmid": "4363503", "title": "Batrachotoxin, an extremely active cardio- and neurotoxin from the Colombian arrow poison frog Phyllobates aurotaenia.", "content": "Batrachotoxin, an extremely active cardio- and neurotoxin from the Colombian arrow poison frog Phyllobates aurotaenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363503"}
{"pmid": "4363507", "title": "Editorial: Status report: feline leukemia.", "content": "Editorial: Status report: feline leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363507"}
{"pmid": "4363508", "title": "Preparation and use of soluble ferritin-antiferritin complexes as a specific marker for immunoelectron microscopy.", "content": "Preparation and use of soluble ferritin-antiferritin complexes as a specific marker for immunoelectron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363508"}
{"pmid": "4363509", "title": "Enzymatic digestion of the first component of human complement (C1q).", "content": "Enzymatic digestion of the first component of human complement (C1q).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363509"}
{"pmid": "4363510", "title": "Abnormalities in the mixed leukocyte reaction during infectious mononucleosis.", "content": "Abnormalities in the mixed leukocyte reaction during infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363510"}
{"pmid": "4363511", "title": "Wilms' tumor in the horseshoe kidney.", "content": "Wilms' tumor in the horseshoe kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363511"}
{"pmid": "4363502", "title": "Physical biochemistry of calcification.", "content": "Physical biochemistry of calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363502"}
{"pmid": "4363512", "title": "3H-actinomycin D binding to DNA localized in ultrathin sections of plastic-embedded biological materials.", "content": "3H-actinomycin D binding to DNA localized in ultrathin sections of plastic-embedded biological materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363512"}
{"pmid": "4363515", "title": "Effect of mitotic inhibitors on C-type virion production.", "content": "Effect of mitotic inhibitors on C-type virion production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363515"}
{"pmid": "4363513", "title": "Comparison of red cell angiotensinase activity in man and animals.", "content": "Comparison of red cell angiotensinase activity in man and animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363513"}
{"pmid": "4363514", "title": "Staining methods of Australia antigen in paraffin section--detection of cytoplasmic inclusion bodies.", "content": "Staining methods of Australia antigen in paraffin section--detection of cytoplasmic inclusion bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363514"}
{"pmid": "4363517", "title": "Endothelial injury and platelet aggregation assoicated with acute lipid mobilization.", "content": "Endothelial injury and platelet aggregation assoicated with acute lipid mobilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363517"}
{"pmid": "4363516", "title": "Toxic metabolites released from rat hepatoma cells in culture. 2. Biological and chemical analyses of toxic metabolites.", "content": "Toxic metabolites released from rat hepatoma cells in culture. 2. Biological and chemical analyses of toxic metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363516"}
{"pmid": "4363518", "title": "Experimental hydrocephalus: surface alterations of the lateral ventricle. Scanning electron microscopic studies.", "content": "Experimental hydrocephalus: surface alterations of the lateral ventricle. Scanning electron microscopic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363518"}
{"pmid": "4363519", "title": "Oncorna virus disease. The syndrome of hemolytic anemia and lymph node cystic disease.", "content": "Oncorna virus disease. The syndrome of hemolytic anemia and lymph node cystic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363519"}
{"pmid": "4363520", "title": "Effect of prophylactic measures on the microbial flora of patients in protected environment units.", "content": "Effect of prophylactic measures on the microbial flora of patients in protected environment units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363520"}
{"pmid": "4363489", "title": "Proceedings: New and simple polarized microscopy.", "content": "Proceedings: New and simple polarized microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363489"}
{"pmid": "4363521", "title": "Studies of resonance energy migration in a heterogeneous pigment complex. I. Heterogeneity as a factor accelerating the localization of electron excitation in traps.", "content": "Studies of resonance energy migration in a heterogeneous pigment complex. I. Heterogeneity as a factor accelerating the localization of electron excitation in traps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363521"}
{"pmid": "4363522", "title": "Conformational changes in spin-labeled antibodies and antigens during specific complex formation.", "content": "Conformational changes in spin-labeled antibodies and antigens during specific complex formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363522"}
{"pmid": "4363523", "title": "Letter: Adrenal responsiveness in chronic hemodialysis.", "content": "Letter: Adrenal responsiveness in chronic hemodialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363523"}
{"pmid": "4363524", "title": "Letter: Neuropathy and methyl N-butyl ketone.", "content": "Letter: Neuropathy and methyl N-butyl ketone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363524"}
{"pmid": "4363525", "title": "Letter: Mechanisms of lithium action.", "content": "Letter: Mechanisms of lithium action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363525"}
{"pmid": "4363536", "title": "Leptomeningeal changes following lumbar myelography with water-soluble contrast media (meglumine iothalamate and methiodal sodium).", "content": "Leptomeningeal changes following lumbar myelography with water-soluble contrast media (meglumine iothalamate and methiodal sodium).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363536"}
{"pmid": "4363537", "title": "A landmark for the choroidal arteries of the fourth ventricle--branches of the posterior inferior cerebellar artery.", "content": "A landmark for the choroidal arteries of the fourth ventricle--branches of the posterior inferior cerebellar artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363537"}
{"pmid": "4363538", "title": "Studies of chicken sarcoma (strain 13). A review.", "content": "Studies of chicken sarcoma (strain 13). A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363538"}
{"pmid": "4363539", "title": "Interdependable effects of magnesium ion and ethylene diamine tetracetate (EDTA) on chicken liver D-fructose-1,6-diphosphate, 1-phosphohydrolase.", "content": "Interdependable effects of magnesium ion and ethylene diamine tetracetate (EDTA) on chicken liver D-fructose-1,6-diphosphate, 1-phosphohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363539"}
{"pmid": "4363540", "title": "Effect of various nucleoside triphosphates on the catalytic activity of chicken liver fructose diphosphatases.", "content": "Effect of various nucleoside triphosphates on the catalytic activity of chicken liver fructose diphosphatases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363540"}
{"pmid": "4363551", "title": "Haptoglobin levels in the plasma of newborn infants with special reference to infections.", "content": "Haptoglobin levels in the plasma of newborn infants with special reference to infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363551"}
{"pmid": "4363552", "title": "Common bile duct obstruction by granular cell tumor (schwannoma).", "content": "Common bile duct obstruction by granular cell tumor (schwannoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363552"}
{"pmid": "4363553", "title": "Hepatoma, erythrocytosis and increased serum erythropoietin developing in long-standing hemochromatosis.", "content": "Hepatoma, erythrocytosis and increased serum erythropoietin developing in long-standing hemochromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363553"}
{"pmid": "4363554", "title": "The history of infectious mononucleosis.", "content": "The history of infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363554"}
{"pmid": "4363556", "title": "Phosphatase activity of anaerobic organisms.", "content": "Phosphatase activity of anaerobic organisms. Anaerobic organisms were tested for phosphatase activity in different pH ranges. Several groups of organisms displayed characteristic patterns. Bacteroides fragilis, B. melaninogenicus, and B. ruminicola produced phosphatase with strongest activity at pH 8.6. Fusobacterium mortiferum was the only species of this genus to show strong hydrolysis. The enzyme was active in both acid and alkaline ranges. The activity of gram-positive organisms was variable, the most active groups being Clostridium perfringens, Peptostreptococcus intermedius, P. micros, and Peptococcus constellatus. The incorporation of phosphatase activity into the identification scheme of anaerobes seems feasible. There was a correlation of hydrolysis with several important pathogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363556"}
{"pmid": "4363555", "title": "Relationship of cellular fatty acid composition to survival of Lactobacillus bulgaricus in liquid nitrogen.", "content": "Relationship of cellular fatty acid composition to survival of Lactobacillus bulgaricus in liquid nitrogen. Concentrated cultures of Lactobacillus bulgaricus were prepared by resuspending cells grown in semisynthetic media in sterile 10% non-fat milk solids. The concentrated cultures were frozen in liquid nitrogen for 24 h. The cell suspensions exhibited decreased viability after storage, and the amount of death varied among the different strains tested. Storage stability of all strains examined was improved by supplementing the growth medium with sodium oleate. Radioisotopes were used to study the fate of sodium oleate with L. bulgaricus NCS1. [1-(14)C]sodium oleate was incorporated solely into the lipid portion of the cells, including both neutral and polar lipids. The fatty acid composition of L. bulgaricus NCS1, NCS2, NCS3, and NCS4 grown with and without sodium oleate was studied. The major fatty acids of strains NCS1, NCS2, and NCS3 grown without sodium oleate were dodecanoic, tetradecanoic, hexadecanoic, hexadecenoic, and octadecenoic acids. In addition to these, strain NCS4 contained C(19) cyclopropane fatty acid. The major fatty acids of all strains grown with sodium oleate were tetradecanoic, hexadecanoic, hexadecenoic, octadecenoic, and C(19) cyclopropane fatty acids. All strains grown in broth containing sodium oleate contained larger amounts of octadecenoic and C(19) cyclopropane fatty acid, and less saturated fatty acids than when grown without sodium oleate. Statistical analyses indicated that C(19) cyclopropane fatty acid was most closely related to stability of the lactobacilli in liquid nitrogen. A negative regression line that was significant at P < 0.001 was obtained when the cellular content of this fatty acid was plotted against death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363555"}
{"pmid": "4363558", "title": "Evaluation of media, time and temperature of incubation, and method of enumeration of several strains fo Clostridium perfringens spores.", "content": "Evaluation of media, time and temperature of incubation, and method of enumeration of several strains fo Clostridium perfringens spores. Two basal media, containing the ingredients found in common in both SPS (BBL) and TSN (BBL) media and in the previously described media of Schaedler et al. (1965) and Starr et al (1971), but minus antibiotics, were selected as the most suitable for the enumeration of Clostridium perfringens spores in a model system. These media were also used to study the influence of the presence of glucose, xylose, or ribose in various concentrations (0, 0.01, 0.1, and 1.0%) on colony morphology and spore recovery. As the sugar concentration in the basal agar medium increased, the colonies of all the test organisms also increased in size, and more of the black colonies became white in color. At the 1.0% sugar level, glucose permitted only white colony development, whereas the pentoses were completely inhibitory. Both pour plates and most-probable-number tubes were inoculated with the spores of several strains of C. perfringens and incubated at 20, 30, 37, and 45 C for 24, 48, and 72 h. Statistical analyses of the enumeration data indicated, at the 99% confidence level, that a Trypticase(BBL)-yeast extract-glucose-sulfite-iron agar gave maximal population estimates at 37 C in 72 h.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363558"}
{"pmid": "4363559", "title": "Requirement for and sensitivity to lysozyme by Clostridium perfringens spores heated at ultrahigh temperatures.", "content": "Requirement for and sensitivity to lysozyme by Clostridium perfringens spores heated at ultrahigh temperatures. The requirement of ultrahigh temperature (UHT)-treated Clostridium perfringens spores for lysozyme and the sensitivity of heated and unheated spores to lysozyme were studied. The UHT-treated spores requiring lysozyme for germination and colony formation originated from only a small portion of the non-UHT-treated spore population. This raised a question of whether the requirement for lysozyme was natural to the spores or was induced by the UHT treatments. However, these spores did not require lysozyme for germination before UHT treatment, which confirmed that the requirement for lysozyme had been induced by the UHT treatment. Only 1 to 2% of the spores were naturally sensitive to lysozyme; therefore, the mere addition of lysozyme to the plating medium did not permit the enumeration of all survivors. Treatment of UHT-treated spores with ethylenediaminetetraacetate (EDTA) sensitized the spores to lysozyme and increased by 10- to 100-fold the number of survivors that were detected on a medium containing lysozyme. Under the heating conditions used, spores that were naturally sensitive to lysozyme and spores that required EDTA treatment were equally heat resistant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363559"}
{"pmid": "4363549", "title": "Ultrastructure of hepatoma cells detected in peritoneal fluid.", "content": "Ultrastructure of hepatoma cells detected in peritoneal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363549"}
{"pmid": "4363557", "title": "Specificity and sensitivity of the streptozyme test for the detection of streptococcal antibodies.", "content": "Specificity and sensitivity of the streptozyme test for the detection of streptococcal antibodies. A comparison between the results of the streptozyme hemagglutination test and serological titers for anti-streptolysin O (ASO), anti-hyaluronidase (AH), anti-deoxyribonuclease B (ADN-B), and anti-nicotinamide adenine dinucleotidase (ANAD) was made in two groups of human sera. In one group, serological titers for all the four antibodies were lower than the threshold of sensitization reported by the producing firm. In the second group, the titer of at least one of the four antibodies was equal to or higher than the threshold. False-positive and false-negative reactions occur with those sera when one or more antibody titer is at or near the threshold of the test as described by the manufacturer. The test was positive for all sera where either the ASO was greater than 166 or the ANAD was greater than 270, and for 98% of the sera with ADN-B greater than 360. It is, therefore, concluded that the streptozyme test can be used as an adjunct to the clinical diagnosis of streptococcal infections and their nonsuppurative sequelae. It is less useful to assess the levels of antibodies in sera from general population surveys. For such sera, the relative specificity and sensitivity of the test might yield misleading results. Until more experience is gained with the test, caution should be used in its application to infant and older adult age groups, where significant streptococcal antibody titers are frequently near the threshold of the test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363557"}
{"pmid": "4363560", "title": "Developmental changes in vascular reactivity in neonatal skeletal muscle.", "content": "Developmental changes in vascular reactivity in neonatal skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363560"}
{"pmid": "4363561", "title": "Aggression, schizophrenic reactions and epilepsy: some transcultural correlations.", "content": "Aggression, schizophrenic reactions and epilepsy: some transcultural correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363561"}
{"pmid": "4363562", "title": "Chronic venous insufficiency. Discussion and case report of statis ulcer treatment.", "content": "Chronic venous insufficiency. Discussion and case report of statis ulcer treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363562"}
{"pmid": "4363564", "title": "Synaptic interactions of reticulospinal neurons and nerve cells in the spinal cord of the sea lamprey.", "content": "Synaptic interactions of reticulospinal neurons and nerve cells in the spinal cord of the sea lamprey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363564"}
{"pmid": "4363565", "title": "The effect of collagenase-inhibitor complexes on collagenolytic activity of normal and inflamed gingival tissue.", "content": "The effect of collagenase-inhibitor complexes on collagenolytic activity of normal and inflamed gingival tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363565"}
{"pmid": "4363563", "title": "Synaptic interactions of identified nerve cells in the spinal cord of the sea lamprey.", "content": "Synaptic interactions of identified nerve cells in the spinal cord of the sea lamprey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363563"}
{"pmid": "4363566", "title": "A light and electron microscopic study of an atypical calcifying odontogenic tumor containing \"amyloid\".", "content": "A light and electron microscopic study of an atypical calcifying odontogenic tumor containing \"amyloid\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363566"}
{"pmid": "4363567", "title": "Electron microscopic studies of organ cultures of tooth germs infected with polyoma virus.", "content": "Electron microscopic studies of organ cultures of tooth germs infected with polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363567"}
{"pmid": "4363568", "title": "A serological survey for selected viral infections of Rocky Mountain bighorn sheep.", "content": "A serological survey for selected viral infections of Rocky Mountain bighorn sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363568"}
{"pmid": "4363571", "title": "Editorial: Myelography.", "content": "Editorial: Myelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363571"}
{"pmid": "4363569", "title": "Bluetongue virus and white-tailed deer in an enzootic area of Texas.", "content": "Bluetongue virus and white-tailed deer in an enzootic area of Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363569"}
{"pmid": "4363572", "title": "Differentiation of blood islands in chick blastoderms in association with Morris hepatoma grafts and its relationship to specific chromosomal changes in the hepatomas.", "content": "Differentiation of blood islands in chick blastoderms in association with Morris hepatoma grafts and its relationship to specific chromosomal changes in the hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363572"}
{"pmid": "4363578", "title": "Angiotensin II- and angiotensin 3-induced aldosterone release vivo in the rat.", "content": "Angiotensin II- and angiotensin 3-induced aldosterone release vivo in the rat. The potential role of angiotensin II and its heptapeptide metabolite, des-aspartyl-angiotensin II, was studied in the conscious unanesthetized rat. Aldosterone release was induced by both peptides at physiologic doses (0.72 nanogram per minute). [I-Sarcosyl-8-alanyl]-angiotensin II (P-113 inhibited angiotensin II more effectively than des-aspartyl-angiotensin II (101 percent as compared to 82 percent). These results indicate that angiotensin controls aldosterone release in the rat and that des-aspartyl-angiotensin II (that is, angiotensin III) may be important in this sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363578"}
{"pmid": "4363583", "title": "Characterization of \"heavy\" and \"light\" SV40-like particles from a patient with PML.", "content": "Characterization of \"heavy\" and \"light\" SV40-like particles from a patient with PML.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363583"}
{"pmid": "4363582", "title": "Host range studies on xenotropic type C viruses in somatic cell hybrids.", "content": "Host range studies on xenotropic type C viruses in somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363582"}
{"pmid": "4363584", "title": "Poliovirus proteins associated with ribosomal structures in infected cells.", "content": "Poliovirus proteins associated with ribosomal structures in infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363584"}
{"pmid": "4363585", "title": "Integration of SV40 DNA and induction of cellular DNA synthesis after a ts SV40 infection.", "content": "Integration of SV40 DNA and induction of cellular DNA synthesis after a ts SV40 infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363585"}
{"pmid": "4363586", "title": "Fractionation of the double-stranded RNA of maize rough dwarf virus subviral particles.", "content": "Fractionation of the double-stranded RNA of maize rough dwarf virus subviral particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363586"}
{"pmid": "4363587", "title": "Adsorption chromatography of polioviruses on porous glass.", "content": "Adsorption chromatography of polioviruses on porous glass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363587"}
{"pmid": "4363588", "title": "Dependence of interferon induction on cell membrane integrity.", "content": "Dependence of interferon induction on cell membrane integrity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363588"}
{"pmid": "4363599", "title": "Skeletal maturation of the hand and wrist, a longitudinal study covering two years among children of Finnish Lapps.", "content": "Skeletal maturation of the hand and wrist, a longitudinal study covering two years among children of Finnish Lapps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363599"}
{"pmid": "4363600", "title": "A comparison between histochemical and biochemical data on the optic lobe of the chicken embryo after unilateral removal of the eye.", "content": "A comparison between histochemical and biochemical data on the optic lobe of the chicken embryo after unilateral removal of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363600"}
{"pmid": "4363601", "title": "\"Caveolated cells\" characterized by deep surface invaginations and abundant filaments in mouse gastro-intestinal epithelia.", "content": "\"Caveolated cells\" characterized by deep surface invaginations and abundant filaments in mouse gastro-intestinal epithelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363601"}
{"pmid": "4363602", "title": "Vinblastine-induced aggregates of smooth endoplasmic reticulum in proximal tubular cells of rat kidney.", "content": "Vinblastine-induced aggregates of smooth endoplasmic reticulum in proximal tubular cells of rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363602"}
{"pmid": "4363603", "title": "An ultrastructural comparison of the uptake and transport of horseradish peroxidase by the rat visceral yolk-sac placenta during mid- and late gestation.", "content": "An ultrastructural comparison of the uptake and transport of horseradish peroxidase by the rat visceral yolk-sac placenta during mid- and late gestation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363603"}
{"pmid": "4363604", "title": "Ultrastructure of the mouse superior cervical ganglion, with particular reference to the pre- and postganglionic elements covering the soma of its principal neurons.", "content": "Ultrastructure of the mouse superior cervical ganglion, with particular reference to the pre- and postganglionic elements covering the soma of its principal neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363604"}
{"pmid": "4363605", "title": "Purification and characterization of a cellular fibrinolytic factor associated with oncogenic transformation: the plasminogen activator from SV-40-transformed hamster cells.", "content": "Purification and characterization of a cellular fibrinolytic factor associated with oncogenic transformation: the plasminogen activator from SV-40-transformed hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363605"}
{"pmid": "4363606", "title": "Effects of glucagon on activities of hepatic enzymes in sheep.", "content": "Effects of glucagon on activities of hepatic enzymes in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363606"}
{"pmid": "4363607", "title": "Pacemaker activity during aggregation in Dictyostelium discoideum.", "content": "Pacemaker activity during aggregation in Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363607"}
{"pmid": "4363608", "title": "Nucleoside triphosphate hydrolase activities of avian vitelline membrane and oviductal lumen.", "content": "Nucleoside triphosphate hydrolase activities of avian vitelline membrane and oviductal lumen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363608"}
{"pmid": "4363609", "title": "Nicotinamide adenine dinucleotide levels in cells of developing chick limbs: possible control of muscle and cartilage development.", "content": "Nicotinamide adenine dinucleotide levels in cells of developing chick limbs: possible control of muscle and cartilage development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363609"}
{"pmid": "4363611", "title": "Red to white fiber ratios as an index of double muscling in beef cattle.", "content": "Red to white fiber ratios as an index of double muscling in beef cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363611"}
{"pmid": "4363612", "title": "Simultaneous measurements in awake rats of drug-induced changes in carotid and tail-cuff systolic pressures.", "content": "Simultaneous measurements in awake rats of drug-induced changes in carotid and tail-cuff systolic pressures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363612"}
{"pmid": "4363614", "title": "Glioblastoma multiforme with remote extracranial metastases.", "content": "Glioblastoma multiforme with remote extracranial metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363614"}
{"pmid": "4363615", "title": "In vitro degradation and stabilization of the glucocorticoid binding component from mouse fibroblasts.", "content": "In vitro degradation and stabilization of the glucocorticoid binding component from mouse fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363615"}
{"pmid": "4363616", "title": "Steroid-receptor in Pseudomonas testosteroni released by osmotic shock.", "content": "Steroid-receptor in Pseudomonas testosteroni released by osmotic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363616"}
{"pmid": "4363617", "title": "Induction of steroid-binding activity in Pseudomonas testosteroni.", "content": "Induction of steroid-binding activity in Pseudomonas testosteroni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363617"}
{"pmid": "4363618", "title": "The influence of synthetic anti-estrogens on the binding of tritiated estradiol-17beta by cytosols of human uterus and human breast carcinoma.", "content": "The influence of synthetic anti-estrogens on the binding of tritiated estradiol-17beta by cytosols of human uterus and human breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363618"}
{"pmid": "4363624", "title": "Otoneurology.", "content": "Otoneurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363624"}
{"pmid": "4363623", "title": "Clinical neurology.", "content": "Clinical neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363623"}
{"pmid": "4363625", "title": "Neuroophthalmology.", "content": "Neuroophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363625"}
{"pmid": "4363626", "title": "Genral neurophysiology (biochemical aspects).", "content": "Genral neurophysiology (biochemical aspects).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363626"}
{"pmid": "4363628", "title": "Peripheral nerve surgery.", "content": "Peripheral nerve surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363628"}
{"pmid": "4363627", "title": "Neuroendocrine relationships.", "content": "Neuroendocrine relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363627"}
{"pmid": "4363629", "title": "Neuropathology.", "content": "Neuropathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363629"}
{"pmid": "4363636", "title": "Neutrophil leukocyte collagenase, elastase and serum protease inhibitors in human gingival crevicles.", "content": "Neutrophil leukocyte collagenase, elastase and serum protease inhibitors in human gingival crevicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363636"}
{"pmid": "4363637", "title": "Two-dimensional polyacrylamide gel electrophoresis separation of low molecular weight nuclear RNA.", "content": "Two-dimensional polyacrylamide gel electrophoresis separation of low molecular weight nuclear RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363637"}
{"pmid": "4363638", "title": "Inhibition of adenosine 3',5'-monophosphate accumulation in anterior pituitary gland in vitro by growth hormone-release inhibiting hormone.", "content": "Inhibition of adenosine 3',5'-monophosphate accumulation in anterior pituitary gland in vitro by growth hormone-release inhibiting hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363638"}
{"pmid": "4363640", "title": "Competitive inhibition of the transport of nucleosides, hypoxanthine, choline and deoxyglucose by theophylline, papaverine and prostaglandins.", "content": "Competitive inhibition of the transport of nucleosides, hypoxanthine, choline and deoxyglucose by theophylline, papaverine and prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363640"}
{"pmid": "4363639", "title": "Inhibition of deoxyribonuclease in an extract of rat liver nuclei by poly(ADP-ribose).", "content": "Inhibition of deoxyribonuclease in an extract of rat liver nuclei by poly(ADP-ribose).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363639"}
{"pmid": "4363641", "title": "\"In vitro\" binding of cellular, alpha-amanitin sensitive, RNA polymerase to infectious, mengovirus-induced double-stranded RNA.", "content": "\"In vitro\" binding of cellular, alpha-amanitin sensitive, RNA polymerase to infectious, mengovirus-induced double-stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363641"}
{"pmid": "4363642", "title": "Corticosterone suppression of ACTH secretion: actinomycin D sensitive and insensitive components of the response.", "content": "Corticosterone suppression of ACTH secretion: actinomycin D sensitive and insensitive components of the response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363642"}
{"pmid": "4363643", "title": "Evidence from the control of pyrimidine biosynthesis in tissue minces by purines.", "content": "Evidence from the control of pyrimidine biosynthesis in tissue minces by purines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363643"}
{"pmid": "4363644", "title": "Studies of vanadium toxicity in the rat. Lack of correlation with molybdenum utilization.", "content": "Studies of vanadium toxicity in the rat. Lack of correlation with molybdenum utilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363644"}
{"pmid": "4363645", "title": "Interactions of parathyroid hormone and plasma membranes from rat kidney.", "content": "Interactions of parathyroid hormone and plasma membranes from rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363645"}
{"pmid": "4363646", "title": "Lymphocyte and polymorphonuclear enzymes in stress. V. Changes associated with a viral infection: Herpes simplex.", "content": "Lymphocyte and polymorphonuclear enzymes in stress. V. Changes associated with a viral infection: Herpes simplex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363646"}
{"pmid": "4363647", "title": "Elevation of hepatic phenylalanine: pyruvate aminotransferase by dibutyryl cyclic AMP in rats.", "content": "Elevation of hepatic phenylalanine: pyruvate aminotransferase by dibutyryl cyclic AMP in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363647"}
{"pmid": "4363648", "title": "A brief review of pulmonary clearance of bacterial aerosols emphasizing aspects of particular relevance to veterinary medicine.", "content": "A brief review of pulmonary clearance of bacterial aerosols emphasizing aspects of particular relevance to veterinary medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363648"}
{"pmid": "4363649", "title": "Combination therapy: some concepts and results.", "content": "Combination therapy: some concepts and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363649"}
{"pmid": "4363650", "title": "Rationale of combined modality therapy for cancer.", "content": "Rationale of combined modality therapy for cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363650"}
{"pmid": "4363651", "title": "In vitro-in vivo studies on the susceptibility of the solid Yoshida sarcoma to drugs and hyperthermia (42 degrees).", "content": "In vitro-in vivo studies on the susceptibility of the solid Yoshida sarcoma to drugs and hyperthermia (42 degrees).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363651"}
{"pmid": "4363652", "title": "5'-Nucleotide phosphodiesterase activity in rat hepatoma.", "content": "5'-Nucleotide phosphodiesterase activity in rat hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363652"}
{"pmid": "4363653", "title": "Alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazone inhibitors of ribonucleoside diphosphate reductase.", "content": "Alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazone inhibitors of ribonucleoside diphosphate reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363653"}
{"pmid": "4363654", "title": "Virus oncogenesis and tumor immunogenicity in the mouse mammary tumor system.", "content": "Virus oncogenesis and tumor immunogenicity in the mouse mammary tumor system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363654"}
{"pmid": "4363655", "title": "In vitro determination of thymidine-3H labeling index in human solid tumors.", "content": "In vitro determination of thymidine-3H labeling index in human solid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363655"}
{"pmid": "4363656", "title": "Beta-aminoisobutyric acid, a new probe for the metabolism of DNA and RNA in normal and tumorous tissue.", "content": "Beta-aminoisobutyric acid, a new probe for the metabolism of DNA and RNA in normal and tumorous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363656"}
{"pmid": "4363657", "title": "Concanavalin A-induced agglutination and tumorigenicity in virally and spontaneously transformed cells derived from BALB-c mice.", "content": "Concanavalin A-induced agglutination and tumorigenicity in virally and spontaneously transformed cells derived from BALB-c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363657"}
{"pmid": "4363658", "title": "Relationship of rat alpha 1-fetoprotein to growth rate and chromosome composition of Morris hepatomas.", "content": "Relationship of rat alpha 1-fetoprotein to growth rate and chromosome composition of Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363658"}
{"pmid": "4363659", "title": "Effects of carcinogens and other agents on histone methylation by a histone arginine methyltransferase purified from rat liver cytoplasm.", "content": "Effects of carcinogens and other agents on histone methylation by a histone arginine methyltransferase purified from rat liver cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363659"}
{"pmid": "4363660", "title": "Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.", "content": "Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363660"}
{"pmid": "4363661", "title": "Isozymes of pyruvate kinase in liver and hepatomas of the rat.", "content": "Isozymes of pyruvate kinase in liver and hepatomas of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363661"}
{"pmid": "4363662", "title": "Isolation of a transplantable cell line induced by the MC29 avian leukosis virus.", "content": "Isolation of a transplantable cell line induced by the MC29 avian leukosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363662"}
{"pmid": "4363663", "title": "Metabolic regulation and adenyl cyclase activity of adrenocortical carcinoma cultured cells.", "content": "Metabolic regulation and adenyl cyclase activity of adrenocortical carcinoma cultured cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363663"}
{"pmid": "4363664", "title": "Separation and characterization of the soluble and insoluble components of insoluble laminaran.", "content": "Separation and characterization of the soluble and insoluble components of insoluble laminaran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363664"}
{"pmid": "4363665", "title": "Chemical analysis of exocellular, acid polysaccharides from seven Rhizobium strains.", "content": "Chemical analysis of exocellular, acid polysaccharides from seven Rhizobium strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363665"}
{"pmid": "4363668", "title": "Improved lipid extraction of erythrocytes.", "content": "Improved lipid extraction of erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363668"}
{"pmid": "4363667", "title": "Quantitative immunoelectrophoresis of plasma proteins in acute viral hepatitis, extrahepatic biliary obstruction, primary biliary cirrhosis and idiopathic haemochromatosis.", "content": "Quantitative immunoelectrophoresis of plasma proteins in acute viral hepatitis, extrahepatic biliary obstruction, primary biliary cirrhosis and idiopathic haemochromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363667"}
{"pmid": "4363669", "title": "Control of mitogen--induced lymphocyte activation.  I. The effect of cyclic AMP on DNA and RNA synthesis in PHA--stimulated cells.", "content": "Control of mitogen--induced lymphocyte activation.  I. The effect of cyclic AMP on DNA and RNA synthesis in PHA--stimulated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363669"}
{"pmid": "4363671", "title": "Pyrophosphate stimulation of calcium uptake into cultured embryonic bones. Fine structure of matrix vesicles and their role in calcification.", "content": "Pyrophosphate stimulation of calcium uptake into cultured embryonic bones. Fine structure of matrix vesicles and their role in calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363671"}
{"pmid": "4363670", "title": "Meeting report Twelfth Midwinter Conference of Immunologists. January 6-9, 1973.", "content": "Meeting report Twelfth Midwinter Conference of Immunologists. January 6-9, 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363670"}
{"pmid": "4363672", "title": "Further studies on the localization of peroxidase in pig thyroid cells.", "content": "Further studies on the localization of peroxidase in pig thyroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363672"}
{"pmid": "4363673", "title": "5Alpha-dihydrotestosterone \"receptor\" in the rat hypophysis.", "content": "5Alpha-dihydrotestosterone \"receptor\" in the rat hypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363673"}
{"pmid": "4363674", "title": "Action of angiotensin on uptake, release and metabolism of 14C-noradrenaline by isolated rabbit hearts.", "content": "Action of angiotensin on uptake, release and metabolism of 14C-noradrenaline by isolated rabbit hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363674"}
{"pmid": "4363676", "title": "Training mental health workers to better meet patient needs.", "content": "Training mental health workers to better meet patient needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363676"}
{"pmid": "4363677", "title": "Using college students as paraprofessionals.", "content": "Using college students as paraprofessionals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363677"}
{"pmid": "4363679", "title": "Mechanism of adrenaline-induced lipolysis in adipose tissue.", "content": "Mechanism of adrenaline-induced lipolysis in adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363679"}
{"pmid": "4363680", "title": "Changes in adenosine 3',5'-monophosphate level and protein kinase activity by glucagon in rat liver nuclei.", "content": "Changes in adenosine 3',5'-monophosphate level and protein kinase activity by glucagon in rat liver nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363680"}
{"pmid": "4363681", "title": "Further investigations on the chemical structure of Forssman globoside obtained from caprine erythrocyte stroma.", "content": "Further investigations on the chemical structure of Forssman globoside obtained from caprine erythrocyte stroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363681"}
{"pmid": "4363682", "title": "Membrane-associated adenosine 3',5'-monophosphate-dependent protein kinase and its substrates in human erythrocytes.", "content": "Membrane-associated adenosine 3',5'-monophosphate-dependent protein kinase and its substrates in human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363682"}
{"pmid": "4363684", "title": "Studies on low temperature spectra of respiratory pigments. II. Spectra of cytochromes in respiratory systems between liquid helium and room temperatures.", "content": "Studies on low temperature spectra of respiratory pigments. II. Spectra of cytochromes in respiratory systems between liquid helium and room temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363684"}
{"pmid": "4363683", "title": "A spin-label study on calcium-induced conformational changes of troponin components.", "content": "A spin-label study on calcium-induced conformational changes of troponin components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363683"}
{"pmid": "4363685", "title": "The formate hydrogenlyase activity of cytochrome c552-deficient mutants of Escherichia coli K12.", "content": "The formate hydrogenlyase activity of cytochrome c552-deficient mutants of Escherichia coli K12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363685"}
{"pmid": "4363686", "title": "Resistance to skin tumorigenesis by 3-methylcholanthrene in mice susceptible to leukemia.", "content": "Resistance to skin tumorigenesis by 3-methylcholanthrene in mice susceptible to leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363686"}
{"pmid": "4363687", "title": "Feline malignant mammary tumors. II. Immunologic and electron microscopic investigations into a possible viral etiology.", "content": "Feline malignant mammary tumors. II. Immunologic and electron microscopic investigations into a possible viral etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363687"}
{"pmid": "4363688", "title": "Tumor grading by implantation in embryos. I. Grading of minimum-deviation hepatomas.", "content": "Tumor grading by implantation in embryos. I. Grading of minimum-deviation hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363688"}
{"pmid": "4363689", "title": "Membrane antigen of bovine papilloma virus-induced fibroma cells.", "content": "Membrane antigen of bovine papilloma virus-induced fibroma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363689"}
{"pmid": "4363690", "title": "Restriction of herpes simplex virus type 1 replication in oncornavirus-transformed cells.", "content": "Restriction of herpes simplex virus type 1 replication in oncornavirus-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363690"}
{"pmid": "4363691", "title": "Type-C RNA virus isolated from SJL-J mice.", "content": "Type-C RNA virus isolated from SJL-J mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363691"}
{"pmid": "4363678", "title": "Influence of catalase and superoxide dismutase on side oxidations involving singlet oxygen.", "content": "Influence of catalase and superoxide dismutase on side oxidations involving singlet oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363678"}
{"pmid": "4363693", "title": "Transplacental effects of 1-ethyl-1-nitrosourea in inbred strains of mice. IV. Rapid tumor induction in strain crosses.", "content": "Transplacental effects of 1-ethyl-1-nitrosourea in inbred strains of mice. IV. Rapid tumor induction in strain crosses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363693"}
{"pmid": "4363692", "title": "Properties of the common antigen associated with Marek's disease herpesvirus and turkey herpesvirus infections.", "content": "Properties of the common antigen associated with Marek's disease herpesvirus and turkey herpesvirus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363692"}
{"pmid": "4363694", "title": "Effect of lifetime administration of 2-hydroxyethylhydrazine on tumorigenesis in hamsters and mice.", "content": "Effect of lifetime administration of 2-hydroxyethylhydrazine on tumorigenesis in hamsters and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363694"}
{"pmid": "4363696", "title": "Spontaneous tumors and C-type virus in polyoma-infected aging wild house mice.", "content": "Spontaneous tumors and C-type virus in polyoma-infected aging wild house mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363696"}
{"pmid": "4363695", "title": "Transplantation studies on polyoma virus-infected cultures of mouse tooth germs.", "content": "Transplantation studies on polyoma virus-infected cultures of mouse tooth germs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363695"}
{"pmid": "4363698", "title": "Additional evidence of type-C particles in human placentas.", "content": "Additional evidence of type-C particles in human placentas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363698"}
{"pmid": "4363699", "title": "Effect of dibutyryl cyclic adenosine 3',5'-monophosphate on in vivo growth of Walker 256 carcinoma: isolation of responsive and unresponsive cell populations.", "content": "Effect of dibutyryl cyclic adenosine 3',5'-monophosphate on in vivo growth of Walker 256 carcinoma: isolation of responsive and unresponsive cell populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363699"}
{"pmid": "4363697", "title": "An attenuated mouse leukemia virus. I. Origin and immunization.", "content": "An attenuated mouse leukemia virus. I. Origin and immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363697"}
{"pmid": "4363700", "title": "Antibodies to Epstein-Barr virus-associated antigens in relatives of cancer patients.", "content": "Antibodies to Epstein-Barr virus-associated antigens in relatives of cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363700"}
{"pmid": "4363701", "title": "B-cell characteristics of human peripheral and cord blood lymphocytes transformed by Epstein-Barr virus.", "content": "B-cell characteristics of human peripheral and cord blood lymphocytes transformed by Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363701"}
{"pmid": "4363702", "title": "Mammary tumor virus in strain GR mice in relation to age and tissue type.", "content": "Mammary tumor virus in strain GR mice in relation to age and tissue type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363702"}
{"pmid": "4363703", "title": "Evaluation of an in vitro assay system for carcinogens based on prior infection of rodent cells with nontransforming RNA tumor virus.", "content": "Evaluation of an in vitro assay system for carcinogens based on prior infection of rodent cells with nontransforming RNA tumor virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363703"}
{"pmid": "4363704", "title": "Diversity of envelope antigens on murine type-C RNA viruses.", "content": "Diversity of envelope antigens on murine type-C RNA viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363704"}
{"pmid": "4363705", "title": "Expression of genes for intracisternal A-particle antigen in somatic cell hybrids.", "content": "Expression of genes for intracisternal A-particle antigen in somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363705"}
{"pmid": "4363706", "title": "C-type virus particles in a reptilian tumor.", "content": "C-type virus particles in a reptilian tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363706"}
{"pmid": "4363707", "title": "Differential effect of ionizing radiation on mammary tumor virus activity associated with blood cells and mammary tumor cells.", "content": "Differential effect of ionizing radiation on mammary tumor virus activity associated with blood cells and mammary tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363707"}
{"pmid": "4363708", "title": "Hemic cell-associated mammary tumor virus activity in BALB-cfC3H mice.", "content": "Hemic cell-associated mammary tumor virus activity in BALB-cfC3H mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363708"}
{"pmid": "4363710", "title": "Stimulated growth of syngeneic tumors at the site of an ongoing delayed-hypersensitivity reaction to tuberculin in BALB-c mice.", "content": "Stimulated growth of syngeneic tumors at the site of an ongoing delayed-hypersensitivity reaction to tuberculin in BALB-c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363710"}
{"pmid": "4363709", "title": "Transmission of mammary tumor virus by the GR mouse strain. I. Role of the virus in the production of lesions.", "content": "Transmission of mammary tumor virus by the GR mouse strain. I. Role of the virus in the production of lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363709"}
{"pmid": "4363711", "title": "Morphology of a \"noninfectious\" sarcoma virus.", "content": "Morphology of a \"noninfectious\" sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363711"}
{"pmid": "4363712", "title": "Procedure for activating Epstein-Barr virus early antigen in nonproducer cells by 5-iododeoxyuridine.", "content": "Procedure for activating Epstein-Barr virus early antigen in nonproducer cells by 5-iododeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363712"}
{"pmid": "4363713", "title": "Cellular immunity in mice with simian virus 40-induced mKSA tumors: comparison of three assays of tumor immunity.", "content": "Cellular immunity in mice with simian virus 40-induced mKSA tumors: comparison of three assays of tumor immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363713"}
{"pmid": "4363715", "title": "Glandular epithelial cells from mice: a method for selective cultivation.", "content": "Glandular epithelial cells from mice: a method for selective cultivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363715"}
{"pmid": "4363714", "title": "Neurotropic effect of 7,12-dimethylbenz(a)anthracene in transplacental carcinogenesis.", "content": "Neurotropic effect of 7,12-dimethylbenz(a)anthracene in transplacental carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363714"}
{"pmid": "4363716", "title": "Ultrastructural comparison of placental virus with several type-c- oncogenic viruses.", "content": "Ultrastructural comparison of placental virus with several type-c- oncogenic viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363716"}
{"pmid": "4363717", "title": "Biogenesis of cocarboxylase in Escherichia coli: regulatory properties of thiamine monophosphate kinase.", "content": "Biogenesis of cocarboxylase in Escherichia coli: regulatory properties of thiamine monophosphate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363717"}
{"pmid": "4363719", "title": "Lipids of cultured hepatoma cells. 3. Triglyceride and phosphoglyceride biosynthesis in minimal deviation hepatoma 7288C.", "content": "Lipids of cultured hepatoma cells. 3. Triglyceride and phosphoglyceride biosynthesis in minimal deviation hepatoma 7288C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363719"}
{"pmid": "4363721", "title": "Diseases in feeder calves.", "content": "Diseases in feeder calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363721"}
{"pmid": "4363720", "title": "On the levels of alkyl and alk-1-enyl glycerolipids in normal and neoplastic tissues: a method of quantification.", "content": "On the levels of alkyl and alk-1-enyl glycerolipids in normal and neoplastic tissues: a method of quantification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363720"}
{"pmid": "4363723", "title": "The functional significance of scolex retraction and subsequent cyst formation in the cysticercoid larva of Hymenolepis microstoma.", "content": "The functional significance of scolex retraction and subsequent cyst formation in the cysticercoid larva of Hymenolepis microstoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363723"}
{"pmid": "4363724", "title": "The tegument of Schistosoma mansoni: observations on the formation, structure and composition of cytoplasmic inclusions in relation to tegument function.", "content": "The tegument of Schistosoma mansoni: observations on the formation, structure and composition of cytoplasmic inclusions in relation to tegument function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363724"}
{"pmid": "4363725", "title": "An in vitro investigation of dynamic processes occurring in the schistosome tegument, using compounds known to disrupt secretory processes.", "content": "An in vitro investigation of dynamic processes occurring in the schistosome tegument, using compounds known to disrupt secretory processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363725"}
{"pmid": "4363722", "title": "Oxaloacetate metabolic crossroads in liver. Enzyme compartmentation and regulation of gluconeogenesis.", "content": "Oxaloacetate metabolic crossroads in liver. Enzyme compartmentation and regulation of gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363722"}
{"pmid": "4363728", "title": "Neonatal islet cell adenoma: case report and literature review.", "content": "Neonatal islet cell adenoma: case report and literature review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363728"}
{"pmid": "4363727", "title": "Liver-spleen scanning in pediatrics.", "content": "Liver-spleen scanning in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363727"}
{"pmid": "4363729", "title": "Studies on hypoglycaemia in primary carcinoma of the liver. A case report and review of pathogenetic mechanisms.", "content": "Studies on hypoglycaemia in primary carcinoma of the liver. A case report and review of pathogenetic mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363729"}
{"pmid": "4363736", "title": "Formation of receptors of glucocorticoid hormones in rat liver chromatin and cytoplasm in ontogenesis.", "content": "Formation of receptors of glucocorticoid hormones in rat liver chromatin and cytoplasm in ontogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363736"}
{"pmid": "4363738", "title": "Action of corticosteroids and ACTH on the chromaffin cells of chick embryo's adrenal glands in organ culture.", "content": "Action of corticosteroids and ACTH on the chromaffin cells of chick embryo's adrenal glands in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363738"}
{"pmid": "4363737", "title": "Differentiation of water-conducting elements in plants.", "content": "Differentiation of water-conducting elements in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363737"}
{"pmid": "4363740", "title": "The morphology of experimental tumours of the nervous system. II. Intracerebral tumours in the rat.", "content": "The morphology of experimental tumours of the nervous system. II. Intracerebral tumours in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363740"}
{"pmid": "4363741", "title": "Oncocytes in the anterior lobe of the human pituitary gland. A light and electron microscopic study.", "content": "Oncocytes in the anterior lobe of the human pituitary gland. A light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363741"}
{"pmid": "4363743", "title": "Heterogeneity and biochemical findings in manic-melancholic disorders.", "content": "Heterogeneity and biochemical findings in manic-melancholic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363743"}
{"pmid": "4363745", "title": "Respiratory control in cytochrome oxidase.", "content": "Respiratory control in cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363745"}
{"pmid": "4363744", "title": "Cyclic 3',5'-adenosine monophosphate stimulates trehalose degradation in baker's yeast.", "content": "Cyclic 3',5'-adenosine monophosphate stimulates trehalose degradation in baker's yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363744"}
{"pmid": "4363746", "title": "A novel property of mitochondrial oxidative phosphorylation.", "content": "A novel property of mitochondrial oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363746"}
{"pmid": "4363747", "title": "Demethylamination of N6-methyldeoxyadenosine by commercial spleen phosphodiesterase preparations.", "content": "Demethylamination of N6-methyldeoxyadenosine by commercial spleen phosphodiesterase preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363747"}
{"pmid": "4363748", "title": "Kinetics of reactions involving C-550 and cytochrome b559 in chloroplasts at low temperature. Evidence for two photoreactions.", "content": "Kinetics of reactions involving C-550 and cytochrome b559 in chloroplasts at low temperature. Evidence for two photoreactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363748"}
{"pmid": "4363749", "title": "A possible termination factor for transcription in Escherichia coli.", "content": "A possible termination factor for transcription in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363749"}
{"pmid": "4363750", "title": "The reaction of the superoxide ion with iron (3) protoporphyrin IX dimethyl ester perchlorate: evidence for a stable dioxygen complex.", "content": "The reaction of the superoxide ion with iron (3) protoporphyrin IX dimethyl ester perchlorate: evidence for a stable dioxygen complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363750"}
{"pmid": "4363751", "title": "The effect of cyclic AMP and related compounds on the control of protein synthesis in reticulocyte lysates.", "content": "The effect of cyclic AMP and related compounds on the control of protein synthesis in reticulocyte lysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363751"}
{"pmid": "4363752", "title": "Cyclic adenosine 3':5'-monophosphate levels in normal and transformed cells of higher plants.", "content": "Cyclic adenosine 3':5'-monophosphate levels in normal and transformed cells of higher plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363752"}
{"pmid": "4363753", "title": "Deuterium and carbon-13 tracer studies of ethanol metabolism in the rat by 2H, 1H-decoupled 13C nuclear magnetic resonance.", "content": "Deuterium and carbon-13 tracer studies of ethanol metabolism in the rat by 2H, 1H-decoupled 13C nuclear magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363753"}
{"pmid": "4363755", "title": "The heme environment in ferric and ferrous cytochrome c oxidase.", "content": "The heme environment in ferric and ferrous cytochrome c oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363755"}
{"pmid": "4363754", "title": "On the specificity and pH dependence of ficin-catalyzed hydrolyses. Some comparisons with bromelain specificity.", "content": "On the specificity and pH dependence of ficin-catalyzed hydrolyses. Some comparisons with bromelain specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363754"}
{"pmid": "4363756", "title": "Influence of globin structure on the state of the heme. 3. Changes in heme spectra accompanying allosteric transitions in methemoglobin and their implications for heme-heme interaction.", "content": "Influence of globin structure on the state of the heme. 3. Changes in heme spectra accompanying allosteric transitions in methemoglobin and their implications for heme-heme interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363756"}
{"pmid": "4363757", "title": "Prefrontal unit activity during delayed alternation in the monkey. I. Relation to direction of response.", "content": "Prefrontal unit activity during delayed alternation in the monkey. I. Relation to direction of response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363757"}
{"pmid": "4363758", "title": "Prefrontal unit activity during delayed alternation in the monkey. II. Relation to absolute versus relative direction of response.", "content": "Prefrontal unit activity during delayed alternation in the monkey. II. Relation to absolute versus relative direction of response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363758"}
{"pmid": "4363759", "title": "Correlation between brain adenyl cyclase activity and spontaneous motor activity in rats after chronic reserpine treatment.", "content": "Correlation between brain adenyl cyclase activity and spontaneous motor activity in rats after chronic reserpine treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363759"}
{"pmid": "4363760", "title": "Early onset in inhibitory functions during synaptogenesis in fetal mouse brain cultures.", "content": "Early onset in inhibitory functions during synaptogenesis in fetal mouse brain cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363760"}
{"pmid": "4363761", "title": "Molecular species and membrane forming properties of lecithins in normal liver and hepatoma.", "content": "Molecular species and membrane forming properties of lecithins in normal liver and hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363761"}
{"pmid": "4363762", "title": "Upper limit of autoregulation of cerebral blood flow in the baboon.", "content": "Upper limit of autoregulation of cerebral blood flow in the baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363762"}
{"pmid": "4363763", "title": "Stimulation of prostaglandin biosynthesis by adenine nucleotides. Profile of prostaglandin release by perfused organs.", "content": "Stimulation of prostaglandin biosynthesis by adenine nucleotides. Profile of prostaglandin release by perfused organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363763"}
{"pmid": "4363767", "title": "Radioimmunoassay of angiotensin I, for estimation of plasma renin activity.", "content": "Radioimmunoassay of angiotensin I, for estimation of plasma renin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363767"}
{"pmid": "4363764", "title": "Depressed fatty acid and acetate oxidation and other metabolic defects in homogenates from hearts of hamsters with hereditary cardiomyopathy.", "content": "Depressed fatty acid and acetate oxidation and other metabolic defects in homogenates from hearts of hamsters with hereditary cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363764"}
{"pmid": "4363766", "title": "Evaluation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides in the hexokinase method for determining glucose in serum.", "content": "Evaluation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides in the hexokinase method for determining glucose in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363766"}
{"pmid": "4363765", "title": "Ontogenesis of the renin-angiotensin system in spontaneously hypertensive and normal Wistar rats.", "content": "Ontogenesis of the renin-angiotensin system in spontaneously hypertensive and normal Wistar rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363765"}
{"pmid": "4363768", "title": "Optic radiation activity during sleep and waking.", "content": "Optic radiation activity during sleep and waking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363768"}
{"pmid": "4363769", "title": "Binding of D-tubocurarine and alpha-bungarotoxin in normal and denervated mouse muscles.", "content": "Binding of D-tubocurarine and alpha-bungarotoxin in normal and denervated mouse muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363769"}
{"pmid": "4363770", "title": "Excitation of cerebral cortical neurons by various polypeptides.", "content": "Excitation of cerebral cortical neurons by various polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363770"}
{"pmid": "4363771", "title": "Electron microscope studies of Fasciola hepatica. XI. Autophagy and parenchymal cell function.", "content": "Electron microscope studies of Fasciola hepatica. XI. Autophagy and parenchymal cell function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363771"}
{"pmid": "4363772", "title": "Hormonal responses to intravenous and oral glucose tolerance testing in a patient with a gastrinoma and a gastrojejunostomy.", "content": "Hormonal responses to intravenous and oral glucose tolerance testing in a patient with a gastrinoma and a gastrojejunostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363772"}
{"pmid": "4363773", "title": "Route of protein loss during a model protein-losing gastropathy in dogs.", "content": "Route of protein loss during a model protein-losing gastropathy in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363773"}
{"pmid": "4363774", "title": "Saccadic discharges evoked by intracellular stimulation of extraocular motoneurons.", "content": "Saccadic discharges evoked by intracellular stimulation of extraocular motoneurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363774"}
{"pmid": "4363775", "title": "Primary afferent hyperpolarization and presynaptic facilitation of Ia afferent terminals induced by large cutaneous fibers.", "content": "Primary afferent hyperpolarization and presynaptic facilitation of Ia afferent terminals induced by large cutaneous fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363775"}
{"pmid": "4363776", "title": "Contribution of nonspecific thalamus to sensory evoked activity in cat postcruciate cortex.", "content": "Contribution of nonspecific thalamus to sensory evoked activity in cat postcruciate cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363776"}
{"pmid": "4363777", "title": "Neural control of circulation in Aplysia. I. Motoneurons.", "content": "Neural control of circulation in Aplysia. I. Motoneurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363777"}
{"pmid": "4363778", "title": "Neural control of circulation in Aplysia. II. Interneurons.", "content": "Neural control of circulation in Aplysia. II. Interneurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363778"}
{"pmid": "4363779", "title": "Furosemide--pharmacology and cellular mode of action.", "content": "Furosemide--pharmacology and cellular mode of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363779"}
{"pmid": "4363780", "title": "The use of multiple systemic antibiotics in the treatment of patients with burns.", "content": "The use of multiple systemic antibiotics in the treatment of patients with burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363780"}
{"pmid": "4363782", "title": "The carcinogenic effect of 2-oxo-propyl-propylnitrosamine in Sprague-Dawley rats.", "content": "The carcinogenic effect of 2-oxo-propyl-propylnitrosamine in Sprague-Dawley rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363782"}
{"pmid": "4363784", "title": "Action of ascorbic--iron combination on the synthesis of blood cells and on the activity of phosphatase enzymes.", "content": "Action of ascorbic--iron combination on the synthesis of blood cells and on the activity of phosphatase enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363784"}
{"pmid": "4363785", "title": "Megakaryocyte abnormalities in thrombotic thrombocytopenic purpura.", "content": "Megakaryocyte abnormalities in thrombotic thrombocytopenic purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363785"}
{"pmid": "4363781", "title": "Experience with infusion and resection in cancer of the liver.", "content": "Experience with infusion and resection in cancer of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363781"}
{"pmid": "4363783", "title": "Energy coupling and extramitochondrial electron transport in slices of Morris hepatoma 3924 A.", "content": "Energy coupling and extramitochondrial electron transport in slices of Morris hepatoma 3924 A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363783"}
{"pmid": "4363786", "title": "Effect of polymyxin B on antibiotic-resistant Proteus mirabilis.", "content": "Effect of polymyxin B on antibiotic-resistant Proteus mirabilis. The surface properties of polymyxin B-resistant Proteus mirabilis are markedly altered by the antibiotic. The effects include the development of susceptibility to surface-active agents such as deoxycholate or tris(hydroxymethyl)aminomethane and a marked increased osmotic fragility. However, cell wall impermeability to various agents such as erythromycin, actinomycin D, bacitracin, lysozyme, and triphenyltetrazolium chloride apparently remains intact. These results support the concept that the actions of the polymyxins on gram-negative bacteria are multiple; the action(s) of the antibiotic responsible for lethality in vitro, presumably at the level of the cytoplasmic membrane, may represent only a portion of the potential therapeutic effects of the antibiotic in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363786"}
{"pmid": "4363788", "title": "Locus of divalent cation inhibition of the bactericidal action of polymyxin B.", "content": "Locus of divalent cation inhibition of the bactericidal action of polymyxin B. The bactericidal effect of polymyxin B upon two Pseudomonas aeruginosa strains and two Escherichia coli strains was studied as a function of the concentration of the divalent cations Ca(2+) and Mg(2+). Lipid spherules in aqueous suspension (liposomes) were prepared from the bacterial phospholipids and were examined for the release of trapped glucose induced by polymyxin B under similar conditions of divalent cation concentration. In contrast to the bacteria, which were protected markedly from the bactericidal action of polymyxin B by Ca(2+) or Mg(2+) at concentrations of 2 x 10(-3)m or less, neither cation had any protective effect on bacterial liposomes at concentrations up to 2 x 10(-2)m. These observations suggest that divalent cations antagonize the bactericidal effect of polymyxin B indirectly through interaction with the cell wall rather than at the primary membrane locus of action. The interaction of the divalent cations with the cell wall prevents access of the antibiotic to the cytoplasmic membrane by mechanisms that remain unclear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363788"}
{"pmid": "4363787", "title": "Standardized antimicrobial disc susceptibility testing of anaerobic bacteria: in vitro susceptibility of Clostridium perfringens to nine antibiotics.", "content": "Standardized antimicrobial disc susceptibility testing of anaerobic bacteria: in vitro susceptibility of Clostridium perfringens to nine antibiotics. The in vitro susceptibility of 43 strains of Clostridium perfringens to nine antibiotics was determined by a standardized test for rapid-growing anaerobes. Good correlation was established between the agar dilution susceptibility and the disc diffusion susceptibility results. The inhibition zone diameters around the antibiotic discs, however, were generally much smaller than those of gram-negative anaerobes previously studied. All of the strains tested were susceptible in vitro to chloramphenicol, clindamycin, doxycycline, minocycline, penicillin, and vancomycin. Erythromycin showed poor in vitro activity against this organism, with only 7% of the strains susceptible, 72% intermediate in susceptibility, and 21% resistant. In tests of the 43 strains against lincomycin, 58% were susceptible, 32.5% were intermediate in susceptibility, and 9.5% were resistant. Against tetracycline, 37% of the strains were intermediate in susceptibility and the rest were susceptible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363787"}
{"pmid": "4363789", "title": "Antiviral action of camptothecin.", "content": "Antiviral action of camptothecin. At a concentration of 10 mum, camptothecin inhibited vaccinia deoxyribonucleic acid (DNA) synthesis in HeLa cells. Inhibition of viral DNA synthesis was observed when the drug was added before infection or at 1 or 2 hr after infection. Inhibitory effects of camptothecin on vaccinia DNA synthesis could be reversed, even after exposure to the alkaloid for 2 hr. Viral DNA, isolated from vaccinia-infected, camptothecin-treated cells, displayed an altered sedimentation constant after alkaline sucrose density gradient centrifugation. Incorporation of uridine into vaccinia messenger ribonucleic acid was inhibited by camptothecin, but the activity of ribonucleic acid polymerase, as tested in isolated vaccinia cores, was not affected by the drug. Camptothecin had essentially no effect on replication of poliovirus in HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363789"}
{"pmid": "4363790", "title": "The Guillain-Barré syndrome. A clinical and electrodiagnostic study of 25 cases.", "content": "The Guillain-Barré syndrome. A clinical and electrodiagnostic study of 25 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363790"}
{"pmid": "4363793", "title": "Pituitary tumours.", "content": "Pituitary tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363793"}
{"pmid": "4363791", "title": "Autonomous breathing. Report of a case.", "content": "Autonomous breathing. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363791"}
{"pmid": "4363794", "title": "Effect of \"medical\" and surgical adrenalectomy on the ventral prostate and other accessory sex glands of the male rat.", "content": "Effect of \"medical\" and surgical adrenalectomy on the ventral prostate and other accessory sex glands of the male rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363794"}
{"pmid": "4363795", "title": "Intermediary mechanisms in asthma. Some informal comments on the pathogenesis of the breathing disturbances.", "content": "Intermediary mechanisms in asthma. Some informal comments on the pathogenesis of the breathing disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363795"}
{"pmid": "4363796", "title": "A cytological and genetic study of oogenesis in Drosophila melanogaster.", "content": "A cytological and genetic study of oogenesis in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363796"}
{"pmid": "4363798", "title": "Microtubules in the cortical region of the egg of Lymnaea during cortical segregation.", "content": "Microtubules in the cortical region of the egg of Lymnaea during cortical segregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363798"}
{"pmid": "4363797", "title": "Protein synthesis and secretion in a myogenic cell line.", "content": "Protein synthesis and secretion in a myogenic cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363797"}
{"pmid": "4363799", "title": "Changes in adenosine 3',5'-monophosphate induced by parathyroid hormone and theophylline in the developing rat renal cortex.", "content": "Changes in adenosine 3',5'-monophosphate induced by parathyroid hormone and theophylline in the developing rat renal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363799"}
{"pmid": "4363800", "title": "Ultrastructural studies of lizard (Anolis carolinensis) myogenesis in vitro.", "content": "Ultrastructural studies of lizard (Anolis carolinensis) myogenesis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363800"}
{"pmid": "4363801", "title": "Inhibition of ribosomal RNA synthesis in neurula cells by extracts from blastulae of Xenopus laevis.", "content": "Inhibition of ribosomal RNA synthesis in neurula cells by extracts from blastulae of Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363801"}
{"pmid": "4363802", "title": "Adhesive specificity in normal and transformed mouse fibroblasts.", "content": "Adhesive specificity in normal and transformed mouse fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363802"}
{"pmid": "4363803", "title": "Stimulation of ciliary activity by low levels of extracellular adenine nucleotides in the amphibian oviduct.", "content": "Stimulation of ciliary activity by low levels of extracellular adenine nucleotides in the amphibian oviduct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363803"}
{"pmid": "4363804", "title": "Preparation and characterization of chick erythrocyte nuclei from heterokaryons.", "content": "Preparation and characterization of chick erythrocyte nuclei from heterokaryons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363804"}
{"pmid": "4363805", "title": "N6-substituted adenines induce cell elongation irrespective of the intracellular cyclic AMP levels.", "content": "N6-substituted adenines induce cell elongation irrespective of the intracellular cyclic AMP levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363805"}
{"pmid": "4363806", "title": "The influence of serum proteins and pH on the effective amino acid concentration in tissue culture medium.", "content": "The influence of serum proteins and pH on the effective amino acid concentration in tissue culture medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363806"}
{"pmid": "4363807", "title": "Suitability of silica sol gradients for purification of cell organelles.", "content": "Suitability of silica sol gradients for purification of cell organelles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363807"}
{"pmid": "4363808", "title": "Different cyclic changes in the surface membrane of normal and malignant transformed cells.", "content": "Different cyclic changes in the surface membrane of normal and malignant transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363808"}
{"pmid": "4363809", "title": "Electron microscope observations on the cell walls of some gram-positive bacteria.", "content": "Electron microscope observations on the cell walls of some gram-positive bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363809"}
{"pmid": "4363810", "title": "Phagocytic activity in the retinal pigment epithelium of the frog Rana pipiens. II. Exclusion of Sarcina subflava.", "content": "Phagocytic activity in the retinal pigment epithelium of the frog Rana pipiens. II. Exclusion of Sarcina subflava.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363810"}
{"pmid": "4363812", "title": "Kupffer cell reactions in rat liver under various conditions as observed in the electron microscope.", "content": "Kupffer cell reactions in rat liver under various conditions as observed in the electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363812"}
{"pmid": "4363811", "title": "Observations on the fine structure and peroxidase cytochemistry of normal rat liver Kupffer cells.", "content": "Observations on the fine structure and peroxidase cytochemistry of normal rat liver Kupffer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363811"}
{"pmid": "4363815", "title": "Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.", "content": "Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363815"}
{"pmid": "4363817", "title": "Paroxysmal signs and symptoms in multiple sclerosis.", "content": "Paroxysmal signs and symptoms in multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363817"}
{"pmid": "4363816", "title": "Adverse interaction between steroid hormones and anticholinesterase drugs.", "content": "Adverse interaction between steroid hormones and anticholinesterase drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363816"}
{"pmid": "4363818", "title": "Morphologic changes associated with combined BCNU and radiation therapy in glioblastoma multiforme.", "content": "Morphologic changes associated with combined BCNU and radiation therapy in glioblastoma multiforme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363818"}
{"pmid": "4363819", "title": "Effect of pentoxifylline on cerebral edema in cats.", "content": "Effect of pentoxifylline on cerebral edema in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363819"}
{"pmid": "4363822", "title": "Endogenously blocked high affinity estradiol receptors in the immature and mature rat uterus.", "content": "Endogenously blocked high affinity estradiol receptors in the immature and mature rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363822"}
{"pmid": "4363823", "title": "Effect of intravenous infusion of isethionate on rats.", "content": "Effect of intravenous infusion of isethionate on rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363823"}
{"pmid": "4363825", "title": "Comparative studies of the viruses rescued from polyoma tumor cell line.", "content": "Comparative studies of the viruses rescued from polyoma tumor cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363825"}
{"pmid": "4363824", "title": "Effects of glucagon and dibutyryl cyclic AMP on the phosphorylase activity and gluconeogenesis in rat liver slices.", "content": "Effects of glucagon and dibutyryl cyclic AMP on the phosphorylase activity and gluconeogenesis in rat liver slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363824"}
{"pmid": "4363826", "title": "Estrogen receptors in bone. An evaluation of the uptake of estrogen into bone cells.", "content": "Estrogen receptors in bone. An evaluation of the uptake of estrogen into bone cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363826"}
{"pmid": "4363828", "title": "Evidence for the involvement of superoxide anion in dopamine-beta-hydroxylase system.", "content": "Evidence for the involvement of superoxide anion in dopamine-beta-hydroxylase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363828"}
{"pmid": "4363829", "title": "Typing of isolates of herpes simplex-virus by mixed agglutination.", "content": "Typing of isolates of herpes simplex-virus by mixed agglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363829"}
{"pmid": "4363827", "title": "Induction of tumors of the stomach and esophagus in inbred Chinese hamsters by oral diethylnitrosamine.", "content": "Induction of tumors of the stomach and esophagus in inbred Chinese hamsters by oral diethylnitrosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363827"}
{"pmid": "4363830", "title": "Pituitary-adrenal function in adult androgenized female rats.", "content": "Pituitary-adrenal function in adult androgenized female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363830"}
{"pmid": "4363833", "title": "Specific unresponsiveness to skin allografts in mice. 3. Synergistic effect of tissue extracts, Bordetella pertussis, and antilymphocytic serum.", "content": "Specific unresponsiveness to skin allografts in mice. 3. Synergistic effect of tissue extracts, Bordetella pertussis, and antilymphocytic serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363833"}
{"pmid": "4363838", "title": "A histochemical study on the interstitial cells of the rat renal medulla.", "content": "A histochemical study on the interstitial cells of the rat renal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363838"}
{"pmid": "4363839", "title": "Liver biopsy.", "content": "Liver biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363839"}
{"pmid": "4363841", "title": "Hyperresponsiveness to lysine-vasopressin in Cushing's disease.", "content": "Hyperresponsiveness to lysine-vasopressin in Cushing's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363841"}
{"pmid": "4363842", "title": "Plasma testosterone in male puberty. I. Physiology of plasma testosterone.", "content": "Plasma testosterone in male puberty. I. Physiology of plasma testosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363842"}
{"pmid": "4363844", "title": "Biological activity of synthetic human corticotropin with revised amino acid sequence.", "content": "Biological activity of synthetic human corticotropin with revised amino acid sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363844"}
{"pmid": "4363843", "title": "The uptake and metabolism of (4-14C)testosterone in human breast cancer growth in organ culture.", "content": "The uptake and metabolism of (4-14C)testosterone in human breast cancer growth in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363843"}
{"pmid": "4363845", "title": "Growth retardation in the Lesch-Nyhan syndrome.", "content": "Growth retardation in the Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363845"}
{"pmid": "4363847", "title": "On the regulation of estrogen production by cortisol and ACTH in human pregnancy at term. Memorial Foundation award thesis.", "content": "On the regulation of estrogen production by cortisol and ACTH in human pregnancy at term. Memorial Foundation award thesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363847"}
{"pmid": "4363846", "title": "Angiography in gastric tumours.", "content": "Angiography in gastric tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363846"}
{"pmid": "4363848", "title": "Herpesvirus infections in pregnancy: a comparison of neutralizing antibody titers in mothers and their infants.", "content": "Herpesvirus infections in pregnancy: a comparison of neutralizing antibody titers in mothers and their infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363848"}
{"pmid": "4363849", "title": "Sodium dodecylsulfate-dependent anomalies in gel electrophoresis: alterations in the banding patterns of foot-and-mouth disease virus polypeptides.", "content": "Sodium dodecylsulfate-dependent anomalies in gel electrophoresis: alterations in the banding patterns of foot-and-mouth disease virus polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363849"}
{"pmid": "4363850", "title": "Activation of DNA primer for DNA polymerase as an ultrasensitive assay for a subgroup of enzymes with deoxyribonuclease activity.", "content": "Activation of DNA primer for DNA polymerase as an ultrasensitive assay for a subgroup of enzymes with deoxyribonuclease activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363850"}
{"pmid": "4363852", "title": "A sensitive analytical method for the detection and quantitation of adenosine in biological samples.", "content": "A sensitive analytical method for the detection and quantitation of adenosine in biological samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363852"}
{"pmid": "4363851", "title": "An improved protein binding assay for cyclic AMP.", "content": "An improved protein binding assay for cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363851"}
{"pmid": "4363853", "title": "A fast and sensitive method for the analysis of modified nucleosides in tRNA.", "content": "A fast and sensitive method for the analysis of modified nucleosides in tRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363853"}
{"pmid": "4363855", "title": "The effect of two synthetic ACTH analogues on the metabolism of biogenic amines in the rat brain.", "content": "The effect of two synthetic ACTH analogues on the metabolism of biogenic amines in the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363855"}
{"pmid": "4363854", "title": "The assay of ATP by the luciferin-luciferase method. Interference by a bacterial phosphatase enzyme stable to perchlorate treatment.", "content": "The assay of ATP by the luciferin-luciferase method. Interference by a bacterial phosphatase enzyme stable to perchlorate treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363854"}
{"pmid": "4363856", "title": "Experimental disciform serous retinal detachment. I. Method of production and histology.", "content": "Experimental disciform serous retinal detachment. I. Method of production and histology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363856"}
{"pmid": "4363857", "title": "Experimental disciform serous retinal detachment. II. Autoradiography of photoreceptor protein metabolism.", "content": "Experimental disciform serous retinal detachment. II. Autoradiography of photoreceptor protein metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363857"}
{"pmid": "4363858", "title": "Pseudomonas blepharoconjunctivitis: a complication of combination chemotherapy.", "content": "Pseudomonas blepharoconjunctivitis: a complication of combination chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363858"}
{"pmid": "4363861", "title": "Studies on the radioiodination of very low density lipoprotein obtained from different mammalian species.", "content": "Studies on the radioiodination of very low density lipoprotein obtained from different mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363861"}
{"pmid": "4363862", "title": "Long-term storage of erythrocytes for quantitative analyses of lipids.", "content": "Long-term storage of erythrocytes for quantitative analyses of lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363862"}
{"pmid": "4363864", "title": "Proceedings: A possible gene assignment to chromosome 21.", "content": "Proceedings: A possible gene assignment to chromosome 21.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363864"}
{"pmid": "4363863", "title": "A review of methods and metabolic studies associated with the radioiodination of lipoproteins.", "content": "A review of methods and metabolic studies associated with the radioiodination of lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363863"}
{"pmid": "4363865", "title": "Proceedings: The human loci for phosphopyruvate hydratase and guanylate kinase are syntenic with the PGD-PGM1 linkage group in man-Chinese hamster somatic cell hybrids.", "content": "Proceedings: The human loci for phosphopyruvate hydratase and guanylate kinase are syntenic with the PGD-PGM1 linkage group in man-Chinese hamster somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363865"}
{"pmid": "4363867", "title": "Proceedings: Assignment of the gene in man for mitochondrial superoxide dismutase (indophenol oxidase-B, tetrameric) to chromosome 6.", "content": "Proceedings: Assignment of the gene in man for mitochondrial superoxide dismutase (indophenol oxidase-B, tetrameric) to chromosome 6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363867"}
{"pmid": "4363866", "title": "Proceedings: The genetics of the antiviral state in human cells.", "content": "Proceedings: The genetics of the antiviral state in human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363866"}
{"pmid": "4363868", "title": "Proceedings: Assignment of the second locus of adenylate kinase to chromosome 1p: preliminary data.", "content": "Proceedings: Assignment of the second locus of adenylate kinase to chromosome 1p: preliminary data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363868"}
{"pmid": "4363869", "title": "Proceedings: Evidence for synteny between the human loci for the HLA histocompatibility antigen, phosphoglucomutase3, malic enzyme (cytoplasmic), and indophenol oxidase B (tetrameric).", "content": "Proceedings: Evidence for synteny between the human loci for the HLA histocompatibility antigen, phosphoglucomutase3, malic enzyme (cytoplasmic), and indophenol oxidase B (tetrameric).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363869"}
{"pmid": "4363870", "title": "Proceedings: Regional assignments of seven enzyme loci on chromosme 1 of man.", "content": "Proceedings: Regional assignments of seven enzyme loci on chromosme 1 of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363870"}
{"pmid": "4363871", "title": "Proceedings: The expression of hepatic functions in mouse hepatoma x human leukocyte hybrids.", "content": "Proceedings: The expression of hepatic functions in mouse hepatoma x human leukocyte hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363871"}
{"pmid": "4363872", "title": "Temperature-sensitive mutations in Drosophila melanogaster. XI. Male sterile mutants of the Y chromosome.", "content": "Temperature-sensitive mutations in Drosophila melanogaster. XI. Male sterile mutants of the Y chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363872"}
{"pmid": "4363873", "title": "Studies of oogenesis in Urechis caupo. II. Accumulation during oogenesis of carbohydrate, RNA, microtubule protein, and soluble, mitochondrial, and lysosomal enzymes.", "content": "Studies of oogenesis in Urechis caupo. II. Accumulation during oogenesis of carbohydrate, RNA, microtubule protein, and soluble, mitochondrial, and lysosomal enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363873"}
{"pmid": "4363874", "title": "Sleep, sleep deprivation, photosensitivity and epilepsy.", "content": "Sleep, sleep deprivation, photosensitivity and epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363874"}
{"pmid": "4363875", "title": "5-Hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid of patients with neurological diseases.", "content": "5-Hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid of patients with neurological diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363875"}
{"pmid": "4363879", "title": "The deoxyribonucleoside transport systems of cultured Novikoff rat hepatoma cells.", "content": "The deoxyribonucleoside transport systems of cultured Novikoff rat hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363879"}
{"pmid": "4363878", "title": "Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells and effects of hydroxyurea.", "content": "Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells and effects of hydroxyurea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363878"}
{"pmid": "4363880", "title": "Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.", "content": "Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363880"}
{"pmid": "4363881", "title": "The effect of calcium concentration on ACTH stimulation of steroidogenesis in mouse adrenal tumor cells.", "content": "The effect of calcium concentration on ACTH stimulation of steroidogenesis in mouse adrenal tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363881"}
{"pmid": "4363883", "title": "The nervous control of autotomy in Carcinus maenas.", "content": "The nervous control of autotomy in Carcinus maenas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363883"}
{"pmid": "4363882", "title": "Plasma membrane ectoglycosyltransferase activity of L1210 murine leukemic cells.", "content": "Plasma membrane ectoglycosyltransferase activity of L1210 murine leukemic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363882"}
{"pmid": "4363884", "title": "Angiofibroma: a treatment approach.", "content": "Angiofibroma: a treatment approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363884"}
{"pmid": "4363885", "title": "The medical and surgical treatment of nasal polyps.", "content": "The medical and surgical treatment of nasal polyps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363885"}
{"pmid": "4363887", "title": "Role of the spleen in membrane conditioning and hemolysis of spur cells in liver disease.", "content": "Role of the spleen in membrane conditioning and hemolysis of spur cells in liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363887"}
{"pmid": "4363888", "title": "Treatment of hyperlipidemia.", "content": "Treatment of hyperlipidemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363888"}
{"pmid": "4363890", "title": "Letter: Hypertension and hydronephrosis.", "content": "Letter: Hypertension and hydronephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363890"}
{"pmid": "4363891", "title": "Studies on the neuropharmacology of papaverine. 3. The inhibition of ganglionic transmission.", "content": "Studies on the neuropharmacology of papaverine. 3. The inhibition of ganglionic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363891"}
{"pmid": "4363889", "title": "Thyroid thermogenesis.", "content": "Thyroid thermogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363889"}
{"pmid": "4363892", "title": "Comparative study of brain scintiphotography, cerebral angiography and pneumencephalography in detection of gliomas.", "content": "Comparative study of brain scintiphotography, cerebral angiography and pneumencephalography in detection of gliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363892"}
{"pmid": "4363893", "title": "The vascular supply of eosinophilic and mixed pituitary adenomas in acromegalic patients.", "content": "The vascular supply of eosinophilic and mixed pituitary adenomas in acromegalic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363893"}
{"pmid": "4363895", "title": "Radioisotope serial brainscanning.", "content": "Radioisotope serial brainscanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363895"}
{"pmid": "4363894", "title": "Aspects of the venous drainage of the pons and the mesencephalon.", "content": "Aspects of the venous drainage of the pons and the mesencephalon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363894"}
{"pmid": "4363896", "title": "Type-specific tumor patterns in the cerebral radioangiography (CRAG): results in 195 patients.", "content": "Type-specific tumor patterns in the cerebral radioangiography (CRAG): results in 195 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363896"}
{"pmid": "4363897", "title": "Functional radioangiographic studies of cerebral vascular haemodynamics (preliminary report).", "content": "Functional radioangiographic studies of cerebral vascular haemodynamics (preliminary report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363897"}
{"pmid": "4363898", "title": "A case of chronic adhesive arachnoiditis after lumbar myelography with methiodal-sodium.", "content": "A case of chronic adhesive arachnoiditis after lumbar myelography with methiodal-sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363898"}
{"pmid": "4363900", "title": "Diagnostic problems of cerebral metastases.", "content": "Diagnostic problems of cerebral metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363900"}
{"pmid": "4363899", "title": "Cytomegalic inclusion diseases; a clinico-pathological correlation.", "content": "Cytomegalic inclusion diseases; a clinico-pathological correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363899"}
{"pmid": "4363904", "title": "Renin-angiotensin activation in hyperacute renal xenograft rejection.", "content": "Renin-angiotensin activation in hyperacute renal xenograft rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363904"}
{"pmid": "4363906", "title": "Erythrocyte association and interferon production by minute virus of mice.", "content": "Erythrocyte association and interferon production by minute virus of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363906"}
{"pmid": "4363907", "title": "Inhibitory effect of sodium cyclamate and sodium saccharin on tumor induction by 2-acetylaminofluorene in rats.", "content": "Inhibitory effect of sodium cyclamate and sodium saccharin on tumor induction by 2-acetylaminofluorene in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363907"}
{"pmid": "4363905", "title": "Activation of the renal erythropoietic factor by a cyclic AMP-dependent protein kinase.", "content": "Activation of the renal erythropoietic factor by a cyclic AMP-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363905"}
{"pmid": "4363908", "title": "Inhibition at the T-cells of the spinothalamic tract: a neurophysiological basis for electrically induced analgesia.", "content": "Inhibition at the T-cells of the spinothalamic tract: a neurophysiological basis for electrically induced analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363908"}
{"pmid": "4363909", "title": "Histochemical enzyme changes in epidermis of manganese-deficient fetal mice.", "content": "Histochemical enzyme changes in epidermis of manganese-deficient fetal mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363909"}
{"pmid": "4363910", "title": "Effects of adrenal steroids on brain function and behavior.", "content": "Effects of adrenal steroids on brain function and behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363910"}
{"pmid": "4363912", "title": "Effects of acute and chronic adminstration of narcotic analgesics on growth hormone and corticotrophin (ACTH) secretion in rats.", "content": "Effects of acute and chronic adminstration of narcotic analgesics on growth hormone and corticotrophin (ACTH) secretion in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363912"}
{"pmid": "4363911", "title": "How do neurones secrete peptides? Exocytosis and its consequences, including \"synaptic vesicle\" formation, in the hypothalamo-neurohypophyseal system.", "content": "How do neurones secrete peptides? Exocytosis and its consequences, including \"synaptic vesicle\" formation, in the hypothalamo-neurohypophyseal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363911"}
{"pmid": "4363913", "title": "Effects of morphine and related drugs on the corticotrophin (ACTH)-stress reaction.", "content": "Effects of morphine and related drugs on the corticotrophin (ACTH)-stress reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363913"}
{"pmid": "4363916", "title": "Behavioral aspects of melanocyte-stimulating hormone (MSH).", "content": "Behavioral aspects of melanocyte-stimulating hormone (MSH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363916"}
{"pmid": "4363915", "title": "The influence of peptides derived from corticotrophin (ACTH) on performance. Structure activity studies.", "content": "The influence of peptides derived from corticotrophin (ACTH) on performance. Structure activity studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363915"}
{"pmid": "4363914", "title": "Antagonism between morphine and the polypeptides ACTH, ACTH1-24 and beta-MSH in the nervous system.", "content": "Antagonism between morphine and the polypeptides ACTH, ACTH1-24 and beta-MSH in the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363914"}
{"pmid": "4363918", "title": "Steroid feedback mechanisms in pituitary-adrenal function.", "content": "Steroid feedback mechanisms in pituitary-adrenal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363918"}
{"pmid": "4363919", "title": "Effect of short-term upright posture on plasma angiotensin II in man.", "content": "Effect of short-term upright posture on plasma angiotensin II in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363919"}
{"pmid": "4363917", "title": "Glucocorticoid binding sites in rat brain: subcellular and anatomical localizations.", "content": "Glucocorticoid binding sites in rat brain: subcellular and anatomical localizations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363917"}
{"pmid": "4363921", "title": "Altered action of parathyroid hormone by chlorpropamide.", "content": "Altered action of parathyroid hormone by chlorpropamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363921"}
{"pmid": "4363922", "title": "Charge to the community: some early effects of a state hospital system's change of policy.", "content": "Charge to the community: some early effects of a state hospital system's change of policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363922"}
{"pmid": "4363923", "title": "The principle of energy transduction in the cytochrome c oxidase region of the respiratory chain.", "content": "The principle of energy transduction in the cytochrome c oxidase region of the respiratory chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363923"}
{"pmid": "4363924", "title": "Energy coupling in cytochrome oxidase.", "content": "Energy coupling in cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363924"}
{"pmid": "4363925", "title": "Enzymic generators of membrane potential in mitochondria.", "content": "Enzymic generators of membrane potential in mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363925"}
{"pmid": "4363928", "title": "Conduction within the cytochrome c molecule.", "content": "Conduction within the cytochrome c molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363928"}
{"pmid": "4363929", "title": "Heme-heme interaction between the cytochromes of the mitochondrial respiratory chain.", "content": "Heme-heme interaction between the cytochromes of the mitochondrial respiratory chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363929"}
{"pmid": "4363930", "title": "Solid state physical mechanisms of biological energy transduction.", "content": "Solid state physical mechanisms of biological energy transduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363930"}
{"pmid": "4363926", "title": "Evaluation of the chemiosmotic interpretation of active transport in bacterial membrane vesicles.", "content": "Evaluation of the chemiosmotic interpretation of active transport in bacterial membrane vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363926"}
{"pmid": "4363927", "title": "The function of cytochrome c.", "content": "The function of cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363927"}
{"pmid": "4363931", "title": "The separation of electrons and protons during electron transfer: the distinction between membrane potentials and transmembrane gradients.", "content": "The separation of electrons and protons during electron transfer: the distinction between membrane potentials and transmembrane gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363931"}
{"pmid": "4363935", "title": "Irreversibility of the alteration in RNA transport induced by an azo-dye carcinogen in the rat liver.", "content": "Irreversibility of the alteration in RNA transport induced by an azo-dye carcinogen in the rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363935"}
{"pmid": "4363936", "title": "Studies on a possible phosphoryl-enzyme intermediate in the catalytic reaction of yeast phosphoglycerate kinase.", "content": "Studies on a possible phosphoryl-enzyme intermediate in the catalytic reaction of yeast phosphoglycerate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363936"}
{"pmid": "4363938", "title": "Choline kinase and choline phosphotransferase in developing fetal rat lung.", "content": "Choline kinase and choline phosphotransferase in developing fetal rat lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363938"}
{"pmid": "4363937", "title": "The incorporation of glycerol into mitochondrial lipids during neonatal renal compensatory growth.", "content": "The incorporation of glycerol into mitochondrial lipids during neonatal renal compensatory growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363937"}
{"pmid": "4363939", "title": "A functional acetylcholine receptor in the human erythrocyte.", "content": "A functional acetylcholine receptor in the human erythrocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363939"}
{"pmid": "4363940", "title": "Formation of mengovirus-like particles in cell-free extracts from virus-infected cells.", "content": "Formation of mengovirus-like particles in cell-free extracts from virus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363940"}
{"pmid": "4363941", "title": "In vivo covalent binding of 14CCl4 metabolites in liver microsomal lipids.", "content": "In vivo covalent binding of 14CCl4 metabolites in liver microsomal lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363941"}
{"pmid": "4363942", "title": "Release of the inhibition of messenger RNA translation in extracts of interferon-treated Ehrlich ascites tumor cells by added transfer RNA.", "content": "Release of the inhibition of messenger RNA translation in extracts of interferon-treated Ehrlich ascites tumor cells by added transfer RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363942"}
{"pmid": "4363944", "title": "The metabolism of very low density lipoprotein and chylomicrons by purified lipoprotein lipase from rat heart and adipose tissue.", "content": "The metabolism of very low density lipoprotein and chylomicrons by purified lipoprotein lipase from rat heart and adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363944"}
{"pmid": "4363943", "title": "Use of a concanavalin A polymer to isolate right side-out vesicles of purified plasma membranes from eukariotic cells.", "content": "Use of a concanavalin A polymer to isolate right side-out vesicles of purified plasma membranes from eukariotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363943"}
{"pmid": "4363946", "title": "Isolation of the plasma membrane of a trypanosomatid flagellate: general characterisation and lipid composition.", "content": "Isolation of the plasma membrane of a trypanosomatid flagellate: general characterisation and lipid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363946"}
{"pmid": "4363947", "title": "Effect of ATP on the intermediary steps of the reaction of the (Na+ plus K+)-dependent enzyme system. 3. Effect on the p-nitrophenylphosphatase activity of the system.", "content": "Effect of ATP on the intermediary steps of the reaction of the (Na+ plus K+)-dependent enzyme system. 3. Effect on the p-nitrophenylphosphatase activity of the system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363947"}
{"pmid": "4363948", "title": "A sensitive method for the bioassay of acetylcholine.", "content": "A sensitive method for the bioassay of acetylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363948"}
{"pmid": "4363949", "title": "Mechanism of the inhibitory actions of some spasmogens on the bradykinin relaxation of the guinea-pig ileum.", "content": "Mechanism of the inhibitory actions of some spasmogens on the bradykinin relaxation of the guinea-pig ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363949"}
{"pmid": "4363951", "title": "A comparison of the utilization of thymine and thymidine for the synthesis of DNA-thymine in Novikoff hepatoma cells.", "content": "A comparison of the utilization of thymine and thymidine for the synthesis of DNA-thymine in Novikoff hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363951"}
{"pmid": "4363953", "title": "GH and ACTH secretion in insulin-induced hypoglycemia in normal children.", "content": "GH and ACTH secretion in insulin-induced hypoglycemia in normal children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363953"}
{"pmid": "4363950", "title": "Effects of cell adhesion of the substratum on the growth of chick embryo fibroblasts.", "content": "Effects of cell adhesion of the substratum on the growth of chick embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363950"}
{"pmid": "4363955", "title": "Stereological analysis of the guinea pig pancreas. I. Analytical model and quantitative description of nonstimulated pancreatic exocrine cells.", "content": "Stereological analysis of the guinea pig pancreas. I. Analytical model and quantitative description of nonstimulated pancreatic exocrine cells. A stereological model which provides detailed quantitative information on the structure of the fasted, nonstimulated gland has been developed for the guinea pig pancreas. The model consists of morphologically defined space and membrane compartments which were used to describe the general composition of the tissue and the specific components of exocrine cells. The results are presented, where appropriate, relative to a cubic centimeter of pancreas, a cubic centimeter of exocrine cell cytoplasm, and to the volume of an average exocrine cell. The exocrine cells, accounting for 82% of the pancreas volume, consisted of 54% cytoplasmic matrix, 22% rough-surfaced endoplasmic reticulum (RER), 8.3% nuclei, 8.1% mitochondria, 6.4% zymogen granules, and 0.7% condensing vacuoles. Their total membrane surface area was distributed as follows: 60% RER, 21% mitochondria, 9.9% Golgi apparatus, 4.8% plasma membranes, 2.6% zymogen granules, 1.8% plasma membrane vesicles, and 0.4% condensing vacuoles. The application of this model to the study of membrane movements associated with the secretory process is discussed within the framework of an analytical approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363955"}
{"pmid": "4363956", "title": "Rapid changes in nucleoside transport induced by growth inhibitors. Studies with neoplastic mast cells.", "content": "Rapid changes in nucleoside transport induced by growth inhibitors. Studies with neoplastic mast cells. Aqueous extracts of murine embryonic or uterine tissue, or [(6)N]O(2)'-dibutyryl 3',5'-adenosine monophosphate (dbc-AMP) which were cytostatic for the murine mastocytoma P815Y in vitro also induced rapid changes in the incorporation of exogenous nucleosides into acid-insoluble material. However, these alterations were not a consequence of growth arrest. Different dose-response curves were obtained for cytostasis and inhibition of [(3)H]-nucleoside incorporation, and changes in [(3)H]thymidine uptake were detected within 15 min of treatment with the inhibitors. Also, there were differential effects of each inhibitor on the incorporation of (3)H-labeled thymidine, uridine, adenosine, or choline into acid-insoluble material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363956"}
{"pmid": "4363957", "title": "Effects of cyclic AMP and Sephadex fractions of chick embryo extract on cloned retinal pigmented epithelium in tissue culture.", "content": "Effects of cyclic AMP and Sephadex fractions of chick embryo extract on cloned retinal pigmented epithelium in tissue culture. The effects of dibutyryl cyclic 3',5'-adenosine monophosphate (BcAMP) and Sephadex G-25 fractions of chick embryo extract on the growth rate, morphology, and pigmentation of normal chick retinal pigmented epithelium (PE) were investigated. Seven cloned PE cell lines were each grown in modified Ham's F-12 medium alone (F-12), or in F-12 supplemented with either high molecular weight (H) or low molecular weight (L) fractions of chick embryo extract. Cells grown in F-12 alone or in L medium formed compact epithelial sheets, whereas cells grown in H had a fibrocytic appearance and formed poorly organized monolayers. In H plus BcAMP, cell morphology was more epithelioid than in H alone, and generally the monolayers appeared more differentiated. Under each of these three culture conditions, 2 x 10(-4) M BCAMP retarded the increase in cell number and decreased the final number of cells per culture dish, but had little effect on plating efficiency. BcAMP also increased the rate of cell adhesion to a plastic substratum. Pigmentation was marked in cultures grown in F-12 or in L alone, but the addition of BcAMP dramatically reduced visible pigmentation. This effect was reversed when BcAMP was removed from the culture medium. Thus BcAMP modifies cell and colonial morphology, rate of cell accumulation, adhesive properties, and pigmentation of normal PE cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363957"}
{"pmid": "4363958", "title": "Characterization of a unique muscle cell line.", "content": "Characterization of a unique muscle cell line. A clonal cell line derived from a mouse neoplasm is described which shares many properties with smooth muscle. The cells have electrically excitable membranes capable of generating overshooting action potentials, and they contract both spontaneously and with electrical stimulation. They respond to the iontophoretic application of acetylcholine with a depolarizing response, and to norepinephrine with a hyperpolarizing response. Electron microscopy reveals that the cells have a morphology similar in many, but not all, respects to that of smooth muscle cells in vivo. The cells secrete soluble collagen-like molecules in addition to several proteins of undefined function. Finally, there is an increase in the specific activities of creatine phosphokinase and myokinase associated with increased cell density and the cessation of cell division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363958"}
{"pmid": "4363959", "title": "Resolution of three distinct populations of nerve endings from rat brain homogenates by zonal isopycnic centrifugation.", "content": "Resolution of three distinct populations of nerve endings from rat brain homogenates by zonal isopycnic centrifugation. Conditions have been established for the fractionation of subcellular components of rat forebrain homogenates by zonal isopycnic equilibration in continuous sucrose density gradients using a B-XIV rotor. The fractions were analyzed biochemically and by ultra-structural morphometry. Starting from postnuclear supernates of forebrain homogenates, it has been possible to resolve three distinct populations of nerve endings from one another, as well as from free mitochondria and myelin fragments. The three types of nerve endings differ in their apparent specific gravity, their biochemical properties, and their ability selectively to accumulate exogenous transmitter substances in vitro. These three particle populations are likely to represent, in order of increasing modal equilibrium density, (a) cholinergic nerve endings, characterized by their high content of acetylcholine, (b) gamma-amino butyric acid (GABA)-containing nerve endings with high glutamate decarboxylase activity and the ability to accumulate exogenous GABA, (c) adrenergic nerve endings that accumulate exogenous dopamine and noradrenaline and exhibit high monoamine oxidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363959"}
{"pmid": "4363960", "title": "Ultrastructural localization of concanavalin A receptors in somatic cell hybrids between normal mouse cells and simian virus 40-transformed rat cells.", "content": "Ultrastructural localization of concanavalin A receptors in somatic cell hybrids between normal mouse cells and simian virus 40-transformed rat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363960"}
{"pmid": "4363961", "title": "Bulk isolation of mouse hepatocyte gap junctions. Characterization of the principal protein, connexin.", "content": "Bulk isolation of mouse hepatocyte gap junctions. Characterization of the principal protein, connexin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363961"}
{"pmid": "4363962", "title": "A single extraction thin-layer chromatographic method in current use.", "content": "A single extraction thin-layer chromatographic method in current use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363962"}
{"pmid": "4363963", "title": "Quantitative spectrodensitometry on morphine and amphetamine on thin layer chromatograms.", "content": "Quantitative spectrodensitometry on morphine and amphetamine on thin layer chromatograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363963"}
{"pmid": "4363964", "title": "Glycosphingolipids from rabbit aorta, plasma, and red blood cells: effects of high cholesterol-high fat diets on fatty acid distribution and quantity of glycosphingolipids.", "content": "Glycosphingolipids from rabbit aorta, plasma, and red blood cells: effects of high cholesterol-high fat diets on fatty acid distribution and quantity of glycosphingolipids. Four glycosphingolipids were isolated from rabbit aorta, plasma, and red blood cells. They were identified, by thin-layer chromatography and by quantitative analysis of hexose and fatty acid, as cerebroside, diglycosyl ceramide, triglycosyl ceramide, and globoside. The rabbits had been maintained on a normal diet or on one of three high cholesterol diets for 180 days. The quantities of the glycosphingolipids and their fatty acid distributions were determined, and comparisons were made between the control and experimental animals. Aorta and plasma glycosphingolipids were more affected by the high cholesterol diets than were those from red blood cells. The effects on aorta and plasma glycosphingolipids were similar. The amount of cerebroside was increased in aorta and plasma in all animals in the experimental groups. The amount was also increased in red blood cells in rabbits from two of the experimental groups. The average fatty acid chain length was greater in the lipids from the experimental animals than in those from the control animals for all measured glycosphingolipids from aorta. The average chain length was also greater in cerebrosides from the experimental animals from all three tissues. Probably the most notable differences in the experimental animals were the increased 24:1/24:0 ratios and the increased concentrations of 24:2. These increases occurred in nearly all samples from plasma and aorta, but not in red blood cells. There was also an increase of total unsaturated fatty acids in aorta cerebrosides from the experimental animals. Except for the increase in 24:2, lard generally caused more deviation from normal than did cottonseed oil when the level of cholesterol in the diet was 1%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363964"}
{"pmid": "4363965", "title": "Inhibition of free fatty acid mobilization by colchicine.", "content": "Inhibition of free fatty acid mobilization by colchicine. Segments of epididymal adipose tissue from normal male rats were incubated with micromolar concentrations of colchicine for different periods of time up to 4 hr, and the mobilization of free fatty acids (FFA) was measured during a subsequent reincubation. Although pretreatment with colchicine did not alter basal unstimulated FFA release, mobilization of FFA in the presence of epinephrine or theophylline was reduced. However, neither lipolysis, as judged by glycerol production, nor cyclic AMP accumulation was impaired under the same conditions. To assess the possibility that colchicine might limit production of fatty acids by accelerating the entry and metabolism of glucose into adipocytes, the metabolism of glucose by adipose tissue was studied. Pretreatment with colchicine did not affect uptake of glucose nor its oxidation to CO(2), although colchicine-treated tissues did have slightly more [(14)C]glucose incorporated into the glyceride moiety of triglyceride. When adipose tissues pretreated with colchicine were incubated in an albumin-free medium, no reduction in FFA production by colchicine was observed. Because no FFA release occurs in albumin-free media, this experiment suggests that colchicine-induced inhibition of FFA mobilization results from impaired extrusion of FFA from adipose cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363965"}
{"pmid": "4363966", "title": "3-Hydroxy-3-methylglutaryl CoA reductase and mevalonate kinase of Neurospora crassa.", "content": "3-Hydroxy-3-methylglutaryl CoA reductase and mevalonate kinase of Neurospora crassa. Two enzymes of polyisoprenoid synthesis, 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase (mevalonate:NADP oxidoreductase [acylating CoA], EC 1.1.1.34) and mevalonate kinase (ATP:mevalonate 5-phosphotransferase, EC 2.7.1.36), are present in the microsomal and soluble fractions of Neurospora crassa, respectively. HMG CoA reductase specifically uses NADPH as reductant and has a K(m) for dl-HMG CoA of 30 micro M. The activities of HMG CoA reductase and mevalonate kinase are low in conidia and increase threefold during the first 12 hr of stationary growth. Maximum specific activities of both enzymes occur when aerial hyphae and conidia first appear (2 days), but total activities peak later (3-4 days). Addition to the growth media of ergosterol or beta-carotene, alone or in combination, does not affect the specific or total activity of either enzyme. The mevalonate kinase of N. crassa, purified 200-fold to a specific activity of 5 micro moles/min/mg, is free from HMG CoA reductase, phosphomevalonate kinase, ATPase, adenylate kinase, and NADH oxidase activities. Mevalonate kinase specifically requires ATP as cosubstrate and exhibits a marked preference for Mg(2+) over Mn(2+), especially at high ratios of divalent metal ion to ATP. Kinase activity is inhibited by p-hydroxymercuribenzoate, and this inhibition is partially prevented by mevalonate or MgATP. Optimum activity occurs at pH 8.0-8.5 and at about 55 degrees C. The Neurospora kinase, like that of hog liver, has a sequential mechanism for substrate addition. The Michaelis constants obtained were 2.8 mM for dl-mevalonate and 1.8 mM for MgATP(-2). Geranyl pyrophosphate is an inhibitor competitive with MgATP (K(i) = 0.11 mM).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363966"}
{"pmid": "4363968", "title": "Structure and composition of sulfatides isolated from livers of patients with metachromatic leukodystrophy: galactosyl sulfatide and lactosyl sulfatide.", "content": "Structure and composition of sulfatides isolated from livers of patients with metachromatic leukodystrophy: galactosyl sulfatide and lactosyl sulfatide. The livers of four patients with metachromatic leukodystrophy contained galactosyl sulfatide and lactosyl sulfatide, whereas these substances were undetectable in normal human liver. On the basis of methanolysis and permethylation studies, both sulfatides were shown to be substituted with sulfate at the C-3 position of the galactose moiety. Examination of the fatty acid compositions of these sulfatides showed that C(22:0) and higher 2-hydroxy and nonhydroxy fatty acids predominated in both. Both sulfatides contained the same long-chain bases, predominantly sphingosine, dihydrosphingosine, and phytosphingosine. Using as criteria the proportion of lactosyl sulfatide to galactosyl sulfatide, and the fatty acid and long-chain base compositions, the liver sulfatides from subjects with metachromatic leukodystrophy closely resemble those in the kidney and differ from those in brain and peripheral nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363968"}
{"pmid": "4363967", "title": "High performance liquid chromatography of ceramides: application to analysis in human tissues and demonstration of ceramide excess in Farber's disease.", "content": "High performance liquid chromatography of ceramides: application to analysis in human tissues and demonstration of ceramide excess in Farber's disease. Conditions have been determined for the benzoylation of ceramides containing nonhydroxy and hydroxy fatty acids, and a high performance liquid chromatography system for the separation and measurement of these derivatives has been devised that is capable of good resolution and high sensitivity. These methods have been used to determine quantitatively the levels of ceramides in human tissues, and in serum and urine, and to demonstrate elevated amounts of ceramide in Farber's disease urine and tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363967"}
{"pmid": "4363969", "title": "Steryl esters and their relationship to normal and diseased human central nervous system.", "content": "Steryl esters and their relationship to normal and diseased human central nervous system. The composition and distribution of steryl esters in human diseased or developing brain tissue has been studied. The abnormal brain conditions included sudanophilic leukodystrophy, multiple sclerosis plaque, subacute sclerosing panencephalitis, and an old cerebral infarction and two types of brain-derived tumors. In addition to the above abnormal tissue, steryl esters were also examined in developing and normal adult human brain. It was found upon subcellular fractionation that the steryl ester was localized mainly in the soluble nonparticulate material. A cholesteryl ester-rich fraction, floating on top of distilled water after centrifugation, was recovered only in the developing brain or in instances where there was myelin damage. The sterol portion of the steryl ester was largely cholesterol. The fatty acid moiety was mainly composed of C(16), C(18), and C(20) fatty acids. The dominant fatty acid was oleic acid, and the proportion of this fatty acid increased in demyelination. Although there were great differences in the quantities of steryl ester found, the fatty acid profiles of normal developing and adult brain were quite similar. As has been noted by others, the fatty acid composition of brain steryl esters most closely resembles that of brain phosphatidylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363969"}
{"pmid": "4363970", "title": "Permeability changes induced by peroxidation in liposomes prepared from human erythrocyte lipids.", "content": "Permeability changes induced by peroxidation in liposomes prepared from human erythrocyte lipids. The diffusion of [2-(14)C]glucose out of liposomes prepared from extracted human erythrocyte lipids was examined. Increased glucose efflux was observed when the lipids were treated with hydrogen peroxide and CuCl(2) before liposome formation, and this phenomenon required both peroxide and metal. Peroxidation of these lipids also resulted in the destruction of polyunsaturated fatty acids and the generation of conjugated dienes, but neither of these processes appeared to be the sole cause of increased glucose efflux. Thin-layer chromatography and the effects of aqueous washes suggested that surface-active lysophosphatides or other lipid degradation products were responsible for the increased permeability of the treated liposomes. It is suggested that the behavior of this liposome model system may be relevant to the high permeability and fragility of vitamin E-deficient erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363970"}
{"pmid": "4363971", "title": "Quantitative determination of lysolecithin and sphingomyelin in phospholipid mixtures by thin-layer chromatography as applied to the thymus of the fmfm mouse.", "content": "Quantitative determination of lysolecithin and sphingomyelin in phospholipid mixtures by thin-layer chromatography as applied to the thymus of the fmfm mouse. Lysolecithin and sphingomyelin may be readily separated from other phospholipids on thin-layer plates impregnated with silver nitrate using the solvent system chloroform-methanol-concentrated ammonium hydroxide 65:35:8. Quantitation is carried out by determining the phosphorus content of the developed bands. The minimum amount of phospholipid that can be quantitatively determined is that which contains 0.7 micro g of phosphorus. This method has been used for the determination of lysolecithin and sphingomyelin in the tissues of mice having foam-cell reticulosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363971"}
{"pmid": "4363973", "title": "Use of stainless steel wire coil prosthesis in treatment of anastomotic dehiscence after cervical tracheal resection.", "content": "Use of stainless steel wire coil prosthesis in treatment of anastomotic dehiscence after cervical tracheal resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363973"}
{"pmid": "4363972", "title": "Simple assay for monoacylglycerol hydrolase activity of rat adipose tissue.", "content": "Simple assay for monoacylglycerol hydrolase activity of rat adipose tissue. A simple, sensitive, and specific assay for monoacylglycerol hydrolase activity of rat adipose tissue is described. Monoacyl[(3)H]glycerols with different chain lengths (8-18 carbon atoms) and different degrees of unsaturation in mixed micellar solution with different detergents can be used as substrates. The [(3)H]glycerol that is produced is isolated in a one-step liquid-liquid partition procedure. For routine purposes monooleoyl[(3)H]glycerol was found to be the most suitable substrate. A simple method for the chemical synthesis and purification of this substrate in high yield is given. The assay allows rapid serial sampling of enzymatic activity with a high reproducibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363972"}
{"pmid": "4363975", "title": "Mucus gland adenoma of the bronchus.", "content": "Mucus gland adenoma of the bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363975"}
{"pmid": "4363974", "title": "Arteriographic findings in mediastinal chemodectoma.", "content": "Arteriographic findings in mediastinal chemodectoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363974"}
{"pmid": "4363978", "title": "Granular-cell tumor. Review of the literature and report of a case.", "content": "Granular-cell tumor. Review of the literature and report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363978"}
{"pmid": "4363979", "title": "The effect of systemic disorders on the dental pulp in experimental animals.", "content": "The effect of systemic disorders on the dental pulp in experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363979"}
{"pmid": "4363983", "title": "Competitive protein-binding assay for corticoids in the peripheral plasma of the immature chicken.", "content": "Competitive protein-binding assay for corticoids in the peripheral plasma of the immature chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363983"}
{"pmid": "4363984", "title": "Isolation and purification of turkey heme proteins.", "content": "Isolation and purification of turkey heme proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363984"}
{"pmid": "4363987", "title": "Steroid metabolism by human breast and rat mammary carcinomata.", "content": "Steroid metabolism by human breast and rat mammary carcinomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363987"}
{"pmid": "4363998", "title": "Dual role of calcium in steroidogenesis in the isolated adrenal cell of rat.", "content": "Dual role of calcium in steroidogenesis in the isolated adrenal cell of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363998"}
{"pmid": "4363999", "title": "A novel form of covalently bound flavin from thiamine dehydrogenase.", "content": "A novel form of covalently bound flavin from thiamine dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4363999"}
{"pmid": "4364000", "title": "Comparative study on the binding of estrogens by human and rat serum proteins in development.", "content": "Comparative study on the binding of estrogens by human and rat serum proteins in development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364000"}
{"pmid": "4364002", "title": "The role of tryptophan in neutral fructose diphosphatase.", "content": "The role of tryptophan in neutral fructose diphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364002"}
{"pmid": "4364003", "title": "A different pattern of insulin release in the perifused islets of the rabbits.", "content": "A different pattern of insulin release in the perifused islets of the rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364003"}
{"pmid": "4364004", "title": "Activity of protein-deficient 30S ribosomal subunits in elongation factor G-dependent GTPAse.", "content": "Activity of protein-deficient 30S ribosomal subunits in elongation factor G-dependent GTPAse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364004"}
{"pmid": "4364001", "title": "Antibiotic mucidin, a new antimycin A-like inhibitor of electron transport in rat liver mitochondria.", "content": "Antibiotic mucidin, a new antimycin A-like inhibitor of electron transport in rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364001"}
{"pmid": "4364005", "title": "Sialic acid residues exposed on mammalian cell surface: the effect of adsorption of denatured virus particles.", "content": "Sialic acid residues exposed on mammalian cell surface: the effect of adsorption of denatured virus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364005"}
{"pmid": "4364008", "title": "A recognition marker required for uptake of a lysosomal enzyme by cultured fibroblasts.", "content": "A recognition marker required for uptake of a lysosomal enzyme by cultured fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364008"}
{"pmid": "4364006", "title": "Linoleic- and linolenic acid dependency of some brain membrane-bound enzymes after lipid deprivation in rats.", "content": "Linoleic- and linolenic acid dependency of some brain membrane-bound enzymes after lipid deprivation in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364006"}
{"pmid": "4364007", "title": "Insulin and non-suppressible insulin-like activity (NSILA-s): evidence for separate plasma membrane receptor sites.", "content": "Insulin and non-suppressible insulin-like activity (NSILA-s): evidence for separate plasma membrane receptor sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364007"}
{"pmid": "4364011", "title": "A fluorescent spot test for the detection of galactokinase deficiency.", "content": "A fluorescent spot test for the detection of galactokinase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364011"}
{"pmid": "4364010", "title": "Immunity to cancer: naturally occurring tumours in domestic animals as models for research. 2.", "content": "Immunity to cancer: naturally occurring tumours in domestic animals as models for research. 2. Part 1 of this Memorandum appeared in Vol. 49, pages 81-91. Part 2 covers neoplasia of the bovine urinary bladder; tumours of unknown cause (including melanomas, osteosarcomas, mammary tumours, lymphosarcomas, mastocytomas, transmissible venereal tumours, and histiocytomas); and the applications of animal models in studies of neoplasia. A summary of animal models is included as an annex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364010"}
{"pmid": "4364012", "title": "Case report No. 16942.", "content": "Case report No. 16942.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364012"}
{"pmid": "4364009", "title": "Phospholipids of adrenal cortex mitochondria and the steroid hydroxylases: the lipid-environment of cytochrome P-450.", "content": "Phospholipids of adrenal cortex mitochondria and the steroid hydroxylases: the lipid-environment of cytochrome P-450.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364009"}
{"pmid": "4364015", "title": "Protein kinase in adipose tissue: effect of hypophysectomy.", "content": "Protein kinase in adipose tissue: effect of hypophysectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364015"}
{"pmid": "4364016", "title": "Renal handling of cortisol in dogs. II. Effect of ACTH on stop flow pattern.", "content": "Renal handling of cortisol in dogs. II. Effect of ACTH on stop flow pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364016"}
{"pmid": "4364017", "title": "The cyclic AMP-mediated action of epinephrine on the activity of carbonic anhydrase in avian erythrocytes.", "content": "The cyclic AMP-mediated action of epinephrine on the activity of carbonic anhydrase in avian erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364017"}
{"pmid": "4364019", "title": "Repair of soft tissue injuries of the face.", "content": "Repair of soft tissue injuries of the face.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364019"}
{"pmid": "4364020", "title": "What is CWIM?", "content": "What is CWIM?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364020"}
{"pmid": "4364018", "title": "Kidney function during anesthesia and hemorrhage.", "content": "Kidney function during anesthesia and hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364018"}
{"pmid": "4364022", "title": "Explanation for the apparent inefficiency of reduced nicotinamide adenine dinucleotide in energizing amino acid transport in membrane vesicles.", "content": "Explanation for the apparent inefficiency of reduced nicotinamide adenine dinucleotide in energizing amino acid transport in membrane vesicles. Lineweaver-Burk plots of reduced nicotinamide adenine dinucleotide (NADH) oxidation by membrane preparations from Bacillus subtilis are biphasic, with two K(m) values for NADH. The higher K(m) corresponds to the only K(m) observed for NADH oxidation by whole cells, whereas the lower K(m) corresponds to that observed with open cell envelopes. Membrane preparations apparently contain a small fraction of open or inverted vesicles which is responsible for the low K(m) reaction, whereas entry of NADH into the larger portion of closed, normally oriented vesicles is rate limiting and responsible for the high K(m) reaction. In contrast, the oxidation of l-alpha-glycerol-phosphate (glycerol-P) by membrane preparations shows only one K(m) that corresponds to that of glycerol-P oxidation by whole cells or lysates. Since glycerol-P dehydrogenase (NAD independent) has the same K(m), this enzyme reaction rather than entry of glycerol-P into vesicles represents the rate-limiting step for glycerol-phosphate oxidation. The K(m) for amino acid uptake by vesicles in the presence of NADH corresponds to the high K(m) for NADH oxidation, indicating that NADH energizes transport only if it enters closed, normally oriented vesicles. Studies with rotenone and proteolytic enzymes support this interpretation. The apparent efficiency of NADH in energizing uptake seems to be lower than that of glycerol-P because, under the experimental conditions usually employed, open or inverted vesicles that do not participate in amino acid uptake are responsible for the major portion of NADH oxidation. When the results are corrected for this effect, the efficiency of NADH is essentially the same as that of l-alpha-glycerol-P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364022"}
{"pmid": "4364024", "title": "Osmiophilic structure in pigment-producing Flavobacterium mutants.", "content": "Osmiophilic structure in pigment-producing Flavobacterium mutants. A highly osmiophilic structure observed in all pigment-producing mutants of Flavobacterium examined is described. Several factors favor the possibility that this structure might be related to pigment synthesis or pigment accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364024"}
{"pmid": "4364023", "title": "Homoserine kinase from Escherichia coli K-12: properties, inhibition by L-threonine, and regulation of biosynthesis.", "content": "Homoserine kinase from Escherichia coli K-12: properties, inhibition by L-threonine, and regulation of biosynthesis. We have partially purified homoserine kinase from a genetically derepressed strain of Escherichia coli K-12. The optimum pH of the enzyme-substrate reaction was 7.8 and the K(m) values for l-homoserine and adenosine 5'-triphosphate were both 3 x 10(-4) M. K(+) (or NH(4) (+)) as well as Mg(2+) were required for its activity. The sedimentation coefficient determined by ultracentrifugation in a sucrose density gradient was 5.0 +/- 0.25S. l-Homoserine was an excellent protector against heat inactivation of homoserine kinase. l-Threonine was a competitive inhibitor of homoserine kinase, suggesting that end-product inhibition of this enzyme plays a role in vivo in the overall regulation of threonine biosynthesis. The specific activity of aspartokinase I-homoserine dehydrogenase I and of homoserine kinase showed a strong positive correlation in extracts from strains under widely varying conditions of genetic or physiological derepression; it was concluded that these two enzymes are coordinately regulated in E. coli K-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364023"}
{"pmid": "4364021", "title": "Intracellular and extracellular nucleotides and related compounds during the development of Myxococcus xanthus.", "content": "Intracellular and extracellular nucleotides and related compounds during the development of Myxococcus xanthus. Changes in nucleotide pools and extracellular nucleotides during the developmental cycle of the myxobacterium Myxococcus xanthus were determined using a high-pressure liquid chromatography nucleotide analyzer. A general increase in all nucleotide pools occurred during the morphological phase of glycerol conversion of vegetative cells to myxospores. The levels of the nucleoside triphosphate pools remained high as the myxospore matured and throughout subsequent germination. Oxidized nicotinamide adenine dinucleotide levels were elevated in the dormant myxospore and then declined during germination. The adenylate energy charge value was 0.85 +/- 0.02 for vegetative cells, germinating myxospores, and 6-h-old myxospores. It was interesting that the value for the so-called dormant myxospore was the same as that characteristic of physiologically active cells. The germinating myxospores excreted large quantities of uracil along with lesser quantities of purine nucleoside monophosphates. Although the source of the extracellular uracil cannot be determined from these experiments, it may have been derived from a shift in base ratios accompanying an assumed ribonucleic acid turnover during germination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364021"}
{"pmid": "4364025", "title": "Lung collagen composition and synthesis. Characterization and changes with age.", "content": "Lung collagen composition and synthesis. Characterization and changes with age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364025"}
{"pmid": "4364027", "title": "Electron spin resonance studies with dioldehydrase. II. The hyperfine structure of proposed radical intermediates derived from isotopic substitution in 2-chloroacetaldehyde.", "content": "Electron spin resonance studies with dioldehydrase. II. The hyperfine structure of proposed radical intermediates derived from isotopic substitution in 2-chloroacetaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364027"}
{"pmid": "4364026", "title": "Electron paramagnetic resonance, 1-H, and 13C nuclear magnetic resonance studies of the interaction of manganese and bicarbonate with ribulose 1, 5-diphosphate carboxylase.", "content": "Electron paramagnetic resonance, 1-H, and 13C nuclear magnetic resonance studies of the interaction of manganese and bicarbonate with ribulose 1, 5-diphosphate carboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364026"}
{"pmid": "4364029", "title": "Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.", "content": "Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364029"}
{"pmid": "4364028", "title": "Adenylate cyclase. A new kinetic analysis of the effects of hormones and fluoride ion.", "content": "Adenylate cyclase. A new kinetic analysis of the effects of hormones and fluoride ion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364028"}
{"pmid": "4364030", "title": "Purification and properties of electron-transferring flavoprotein from Peptostreptococcus elsdenii.", "content": "Purification and properties of electron-transferring flavoprotein from Peptostreptococcus elsdenii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364030"}
{"pmid": "4364031", "title": "Phosphorylation of acid-soluble nucleolar proteins of Novikoff hepatoma ascites cells in vivo.", "content": "Phosphorylation of acid-soluble nucleolar proteins of Novikoff hepatoma ascites cells in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364031"}
{"pmid": "4364032", "title": "Properties of gonadotropin receptors in the cell membranes of bovine corpus luteum.", "content": "Properties of gonadotropin receptors in the cell membranes of bovine corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364032"}
{"pmid": "4364033", "title": "Oxidation and reduction of soluble cytochrome c by membrane-bound oxidase and reductase systems.", "content": "Oxidation and reduction of soluble cytochrome c by membrane-bound oxidase and reductase systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364033"}
{"pmid": "4364034", "title": "Regulation of the L-arabinose operon BAD in vitro.", "content": "Regulation of the L-arabinose operon BAD in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364034"}
{"pmid": "4364036", "title": "Averaged encephalic response of aphasics to linguistic and nonlinguistic auditory stimuli.", "content": "Averaged encephalic response of aphasics to linguistic and nonlinguistic auditory stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364036"}
{"pmid": "4364037", "title": "Influence of stimulus level and sleep stage on the early components of the averaged electroencephalic response to clicks during all-night sleep.", "content": "Influence of stimulus level and sleep stage on the early components of the averaged electroencephalic response to clicks during all-night sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364037"}
{"pmid": "4364035", "title": "Surveillance of viral infections at the National Taiwan University Hospital.", "content": "Surveillance of viral infections at the National Taiwan University Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364035"}
{"pmid": "4364040", "title": "Cyclic nucleotide phosphodiesterase activity in rat adrenal gland zones.", "content": "Cyclic nucleotide phosphodiesterase activity in rat adrenal gland zones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364040"}
{"pmid": "4364039", "title": "Stimulation of brain aromatic alkylamine N-methyltransferase activity by FAD and methylcobalamin.", "content": "Stimulation of brain aromatic alkylamine N-methyltransferase activity by FAD and methylcobalamin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364039"}
{"pmid": "4364042", "title": "Composition of myelin. Enzymes.", "content": "Composition of myelin. Enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364042"}
{"pmid": "4364041", "title": "Effects of hormone treatment and age on the stimulation of rat anterior pituitary adenylate cyclase and cyclic adenosine 3',5' monophosphate by hypothalamic extract.", "content": "Effects of hormone treatment and age on the stimulation of rat anterior pituitary adenylate cyclase and cyclic adenosine 3',5' monophosphate by hypothalamic extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364041"}
{"pmid": "4364055", "title": "Proceedings: The immunizing potency of foot-and-mouth disease virus vaccines for swines.", "content": "Proceedings: The immunizing potency of foot-and-mouth disease virus vaccines for swines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364055"}
{"pmid": "4364054", "title": "Proceedings: Quantitative assay of the immunizing dose of monovalent vaccines against foot-and-mouth disease prepared from the virus propagated on cattle tongue mucosa and in culture after Frenkel.", "content": "Proceedings: Quantitative assay of the immunizing dose of monovalent vaccines against foot-and-mouth disease prepared from the virus propagated on cattle tongue mucosa and in culture after Frenkel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364054"}
{"pmid": "4364056", "title": "Proceedings: Isolation of various types of enteroviruses from ill children from a nursery school.", "content": "Proceedings: Isolation of various types of enteroviruses from ill children from a nursery school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364056"}
{"pmid": "4364057", "title": "Proceedings: The role of vegetables in spread of enteroviruses. I. The presence of poliovirus in overground parts of the plants cultivated on infected soil.", "content": "Proceedings: The role of vegetables in spread of enteroviruses. I. The presence of poliovirus in overground parts of the plants cultivated on infected soil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364057"}
{"pmid": "4364058", "title": "Proceedings: Cow teat inflammation due to a poxvirus.", "content": "Proceedings: Cow teat inflammation due to a poxvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364058"}
{"pmid": "4364044", "title": "Action of two hypothalamic factors (TRH, MIF) and of angiotensin II on the behavioral effects of L-DOPA and 5-hydroxytryptophan in mice.", "content": "Action of two hypothalamic factors (TRH, MIF) and of angiotensin II on the behavioral effects of L-DOPA and 5-hydroxytryptophan in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364044"}
{"pmid": "4364060", "title": "A tissue culture system for studies of the regulation of ether-linked and ester-linked aliphatic moieties in glycerolipids.", "content": "A tissue culture system for studies of the regulation of ether-linked and ester-linked aliphatic moieties in glycerolipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364060"}
{"pmid": "4364061", "title": "Inhibition of subtilisin by boronic acids, potential analogs of tetrahedral reaction intermediates.", "content": "Inhibition of subtilisin by boronic acids, potential analogs of tetrahedral reaction intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364061"}
{"pmid": "4364062", "title": "The occurrence of beta-glucocerebrosidase activity in the glucocerebroside-rich deposits of Gaucher's disease.", "content": "The occurrence of beta-glucocerebrosidase activity in the glucocerebroside-rich deposits of Gaucher's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364062"}
{"pmid": "4364063", "title": "Studies on the in vitro transcription and translation of the lac operon.", "content": "Studies on the in vitro transcription and translation of the lac operon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364063"}
{"pmid": "4364064", "title": "Increased response to catecholamines of the cyclic AMP system of rat pineal gland induced by decreased sympathetic activity.", "content": "Increased response to catecholamines of the cyclic AMP system of rat pineal gland induced by decreased sympathetic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364064"}
{"pmid": "4364065", "title": "Characterization of the threonine-sensitive aspartokinase--homoserine dehydrogenase of Escherichia coli K12 by transient electric birefringence.", "content": "Characterization of the threonine-sensitive aspartokinase--homoserine dehydrogenase of Escherichia coli K12 by transient electric birefringence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364065"}
{"pmid": "4364067", "title": "Rapid purification of lactate dehydrogenase from rat liver and hepatoma: a new approach.", "content": "Rapid purification of lactate dehydrogenase from rat liver and hepatoma: a new approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364067"}
{"pmid": "4364068", "title": "Pseudomonas putida cytochrome P-450. Binding of a spin-labeled analog of the inhibitor metyrapone.", "content": "Pseudomonas putida cytochrome P-450. Binding of a spin-labeled analog of the inhibitor metyrapone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364068"}
{"pmid": "4364069", "title": "Prolyl hydroxylase and an immunologically related protein in mammalian tissues.", "content": "Prolyl hydroxylase and an immunologically related protein in mammalian tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364069"}
{"pmid": "4364070", "title": "Subcellular location of rat liver calciferol-25-hydroxylase.", "content": "Subcellular location of rat liver calciferol-25-hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364070"}
{"pmid": "4364071", "title": "Changes in membrane lipid structure of illuminated chloroplasts: studies with spin-labeled and freeze-fractured membranes.", "content": "Changes in membrane lipid structure of illuminated chloroplasts: studies with spin-labeled and freeze-fractured membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364071"}
{"pmid": "4364072", "title": "Apocrine hidrocystoma (cystademnoma).", "content": "Apocrine hidrocystoma (cystademnoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364072"}
{"pmid": "4364076", "title": "Effect of the sodium salt and ethyl ester of alpha-p-chlorophenoxyisobutyric acid (clofibrate) on a fat-mobilizing factor in serum.", "content": "Effect of the sodium salt and ethyl ester of alpha-p-chlorophenoxyisobutyric acid (clofibrate) on a fat-mobilizing factor in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364076"}
{"pmid": "4364084", "title": "Vesicle ultrastructure and RNA synthesis during male meiosis of Glossina austeni (Diptera, Glossinidae).", "content": "Vesicle ultrastructure and RNA synthesis during male meiosis of Glossina austeni (Diptera, Glossinidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364084"}
{"pmid": "4364082", "title": "The activity of 2',3'-cyclic adenosine monophosphate 3'-phosphoesterhydrolase in elasmobranch and teleost brain.", "content": "The activity of 2',3'-cyclic adenosine monophosphate 3'-phosphoesterhydrolase in elasmobranch and teleost brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364082"}
{"pmid": "4364083", "title": "Lysosomal and mitochondrial enzymes in avian muscle.", "content": "Lysosomal and mitochondrial enzymes in avian muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364083"}
{"pmid": "4364085", "title": "Subcellular distributions of catalase in rat skeletal muscle.", "content": "Subcellular distributions of catalase in rat skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364085"}
{"pmid": "4364077", "title": "The fatty acid composition of cholesteryl esters, phospholipids and triglycerides of the baboon, Papio ursinus.", "content": "The fatty acid composition of cholesteryl esters, phospholipids and triglycerides of the baboon, Papio ursinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364077"}
{"pmid": "4364074", "title": "Lipid deposits in ageing human arteries, tendons and fascia.", "content": "Lipid deposits in ageing human arteries, tendons and fascia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364074"}
{"pmid": "4364089", "title": "Gas phase analytical methods for the study of human metabolites. Metabolic profiles obtained by open tubular capillary chromatography.", "content": "Gas phase analytical methods for the study of human metabolites. Metabolic profiles obtained by open tubular capillary chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364089"}
{"pmid": "4364073", "title": "Clinical and metabolic effects of pentaerythritol tetranicotinate in combination with cholesolvin or clofibrate.", "content": "Clinical and metabolic effects of pentaerythritol tetranicotinate in combination with cholesolvin or clofibrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364073"}
{"pmid": "4364091", "title": "Effect of increased aortic perfusion pressure on fluorescent emission of the isolated rat heart.", "content": "Effect of increased aortic perfusion pressure on fluorescent emission of the isolated rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364091"}
{"pmid": "4364093", "title": "The after care project: a viable alternative to home care.", "content": "The after care project: a viable alternative to home care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364093"}
{"pmid": "4364092", "title": "Inhibition of central pressor effects of agiotensin I and II.", "content": "Inhibition of central pressor effects of agiotensin I and II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364092"}
{"pmid": "4364080", "title": "Infectious bursal disease virus: growth and characterization in cell cultures.", "content": "Infectious bursal disease virus: growth and characterization in cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364080"}
{"pmid": "4364081", "title": "Arrhenoblastoma in a chukar partridge.", "content": "Arrhenoblastoma in a chukar partridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364081"}
{"pmid": "4364079", "title": "Composition and concentration of apolipoproteins in very-low-and low-density lipoproteins of normal human plasma.", "content": "Composition and concentration of apolipoproteins in very-low-and low-density lipoproteins of normal human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364079"}
{"pmid": "4364097", "title": "Norepinephrine--an antagonist of dibutyryl cyclic AMP in the regulation of narcosis in the rat.", "content": "Norepinephrine--an antagonist of dibutyryl cyclic AMP in the regulation of narcosis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364097"}
{"pmid": "4364098", "title": "Cytomegalovirus antibody in uremic patients prior to renal transplantation.", "content": "Cytomegalovirus antibody in uremic patients prior to renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364098"}
{"pmid": "4364078", "title": "Serum lipoproteins in pigs on high-cholesterol-high-triglyceride diets.", "content": "Serum lipoproteins in pigs on high-cholesterol-high-triglyceride diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364078"}
{"pmid": "4364112", "title": "The influence of angiotensin II and of adrenaline on the critical opening pressure of vessels in forearm skin. Evidence for a qualitatively different response to angiotensin II in vessels of forearm skin from that in some digital vessels.", "content": "The influence of angiotensin II and of adrenaline on the critical opening pressure of vessels in forearm skin. Evidence for a qualitatively different response to angiotensin II in vessels of forearm skin from that in some digital vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364112"}
{"pmid": "4364113", "title": "A contrast in vascular reactivity between two kinds of experimental hypertension studied by measurements of the critical opening pressure of tail vessels in the conscious rat.", "content": "A contrast in vascular reactivity between two kinds of experimental hypertension studied by measurements of the critical opening pressure of tail vessels in the conscious rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364113"}
{"pmid": "4364114", "title": "Heat treatment of rat liver denosine 3':5'-monophosphate phosphodiesterase. Kinetic characterization of the low affinity enzyme.", "content": "Heat treatment of rat liver denosine 3':5'-monophosphate phosphodiesterase. Kinetic characterization of the low affinity enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364114"}
{"pmid": "4364115", "title": "Fructose-1,6-diphosphatase from rat liver. Purification and properties.", "content": "Fructose-1,6-diphosphatase from rat liver. Purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364115"}
{"pmid": "4364116", "title": "Specificities of rat alkaline ribonucleases and cytochemical localization of pancreatic-like ribonucleases.", "content": "Specificities of rat alkaline ribonucleases and cytochemical localization of pancreatic-like ribonucleases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364116"}
{"pmid": "4364118", "title": "Dihydroxyacetone sulfate as substrate analogue for alpha-glycerol phosphate dehydrogenase.", "content": "Dihydroxyacetone sulfate as substrate analogue for alpha-glycerol phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364118"}
{"pmid": "4364117", "title": "Nucleotide and divalent cation interactions with the (Na+ plus K+)-dependent ATPase.", "content": "Nucleotide and divalent cation interactions with the (Na+ plus K+)-dependent ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364117"}
{"pmid": "4364119", "title": "The inhibition by saccharin and cyclamate of phosphotransferase and phosphohydrolase activities of glucose-6-phosphatase.", "content": "The inhibition by saccharin and cyclamate of phosphotransferase and phosphohydrolase activities of glucose-6-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364119"}
{"pmid": "4364120", "title": "Inorganic pyrophosphate-phosphohydrolytic activity associated with human placental alkaline orthophosphatase. Nature of the substrate and role of magnesium.", "content": "Inorganic pyrophosphate-phosphohydrolytic activity associated with human placental alkaline orthophosphatase. Nature of the substrate and role of magnesium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364120"}
{"pmid": "4364121", "title": "Stereochemistry of hydrogen transfer between pyridine nucleotide and some intermediates of cholesterol catabolism catalyzed by liver alcohol and aldehyde dehydrogenase.", "content": "Stereochemistry of hydrogen transfer between pyridine nucleotide and some intermediates of cholesterol catabolism catalyzed by liver alcohol and aldehyde dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364121"}
{"pmid": "4364122", "title": "Studies on cyclic nucleotides in the adrenal gland. 3. Properties of cyclic AMP- and GMP-dependent protein kinases in the adrenal gland.", "content": "Studies on cyclic nucleotides in the adrenal gland. 3. Properties of cyclic AMP- and GMP-dependent protein kinases in the adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364122"}
{"pmid": "4364124", "title": "Inhibitors of glucagon inactivation. Effect on glucagon--receptor interactions and glucagon-stimulated adenylate cyclase activity in liver cell membranes.", "content": "Inhibitors of glucagon inactivation. Effect on glucagon--receptor interactions and glucagon-stimulated adenylate cyclase activity in liver cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364124"}
{"pmid": "4364123", "title": "Rabbit muscle L-glycerol-3-phosphate dehydrogenase. Substrate activity of 3,4-dihydroxybutyl 1-phosphonate and 4-hydroxy-3-oxobutyl 1-phosphonate.", "content": "Rabbit muscle L-glycerol-3-phosphate dehydrogenase. Substrate activity of 3,4-dihydroxybutyl 1-phosphonate and 4-hydroxy-3-oxobutyl 1-phosphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364123"}
{"pmid": "4364125", "title": "Adenosine 3',5'-cyclic monophosphate in higher plants: assay, distribution and age-dependency.", "content": "Adenosine 3',5'-cyclic monophosphate in higher plants: assay, distribution and age-dependency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364125"}
{"pmid": "4364126", "title": "Analogs of alpha-tocopherol as inhibitors of cyclic-AMP and cyclic-GMP phosphodiesterases and effects of alpha-tocopherol deficiency on cyclic AMP-controlled metabolism.", "content": "Analogs of alpha-tocopherol as inhibitors of cyclic-AMP and cyclic-GMP phosphodiesterases and effects of alpha-tocopherol deficiency on cyclic AMP-controlled metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364126"}
{"pmid": "4364127", "title": "Formation, accumulation and release of adenosine 3',5'-monophosphate induced by histamine in the superior cervical ganglion of the rat in vitro.", "content": "Formation, accumulation and release of adenosine 3',5'-monophosphate induced by histamine in the superior cervical ganglion of the rat in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364127"}
{"pmid": "4364129", "title": "Protein-bound carbohydrate content of normal and tumorous human lung tissue.", "content": "Protein-bound carbohydrate content of normal and tumorous human lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364129"}
{"pmid": "4364128", "title": "Regulation of fructose metabolism in the perfused rat liver. Interrelation with inorganic phosphate, glucose, ketone body and ethanol metabolism.", "content": "Regulation of fructose metabolism in the perfused rat liver. Interrelation with inorganic phosphate, glucose, ketone body and ethanol metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364128"}
{"pmid": "4364130", "title": "Alterations in adenylate cyclase activity of the rat prostate gland.", "content": "Alterations in adenylate cyclase activity of the rat prostate gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364130"}
{"pmid": "4364131", "title": "Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats.", "content": "Effects of glucagon on cyclic AMP and carbohydrate metabolism in livers from diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364131"}
{"pmid": "4364132", "title": "Insulin receptors in murine mammary cells: comparison in pregnant and nonpregnant animals.", "content": "Insulin receptors in murine mammary cells: comparison in pregnant and nonpregnant animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364132"}
{"pmid": "4364133", "title": "Studies of the metabolism of asialotransferrins: potentiation of the catabolism of human asialotransferrin in the rabbit.", "content": "Studies of the metabolism of asialotransferrins: potentiation of the catabolism of human asialotransferrin in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364133"}
{"pmid": "4364134", "title": "Changes in the adenyl cyclase system of skeletal muscle of cold-acclimated rats.", "content": "Changes in the adenyl cyclase system of skeletal muscle of cold-acclimated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364134"}
{"pmid": "4364135", "title": "Studies on corticosterone-receptor complexes from mouse placenta.", "content": "Studies on corticosterone-receptor complexes from mouse placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364135"}
{"pmid": "4364136", "title": "Biosynthesis of the diguanosine nucleotides. II. Mechanism of action of GTP:GTP guanylyltransferase on nucleotide metabolism in brine shrimp embryos.", "content": "Biosynthesis of the diguanosine nucleotides. II. Mechanism of action of GTP:GTP guanylyltransferase on nucleotide metabolism in brine shrimp embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364136"}
{"pmid": "4364137", "title": "Inhibition of lipogenesis by cylic AMP without altered lipolysis.", "content": "Inhibition of lipogenesis by cylic AMP without altered lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364137"}
{"pmid": "4364138", "title": "Effects of actinomycin D on purine ribonucleotide metabolism in Ehrlich ascites tumor cells in vitro.", "content": "Effects of actinomycin D on purine ribonucleotide metabolism in Ehrlich ascites tumor cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364138"}
{"pmid": "4364139", "title": "Pyrimidine metabolism in Pseudomonas acidovorans.", "content": "Pyrimidine metabolism in Pseudomonas acidovorans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364139"}
{"pmid": "4364141", "title": "Characteristics of a reserve alpha-glucan from Clostridium pasteurianum.", "content": "Characteristics of a reserve alpha-glucan from Clostridium pasteurianum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364141"}
{"pmid": "4364140", "title": "Sequential action of cell wall hydrolases in the germination and outgrowth of Microsporum gypseum macroconidia.", "content": "Sequential action of cell wall hydrolases in the germination and outgrowth of Microsporum gypseum macroconidia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364140"}
{"pmid": "4364142", "title": "Morphologic and functional studies in lymph nodes regional to cancer.", "content": "Morphologic and functional studies in lymph nodes regional to cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364142"}
{"pmid": "4364146", "title": "A comparison of the properties of FSH from several species as determined by a rat testis tubule receptor assay.", "content": "A comparison of the properties of FSH from several species as determined by a rat testis tubule receptor assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364146"}
{"pmid": "4364147", "title": "The mechanism of frog skin lightening by acetylcholine.", "content": "The mechanism of frog skin lightening by acetylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364147"}
{"pmid": "4364148", "title": "Adhesion of red cells to foreign surfaces in the presence of flow.", "content": "Adhesion of red cells to foreign surfaces in the presence of flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364148"}
{"pmid": "4364151", "title": "Extracellular lipids of Pseudomonas aeruginosa NCTC2000 obtained by n-butanol extraction of stationary liquid cultures.", "content": "Extracellular lipids of Pseudomonas aeruginosa NCTC2000 obtained by n-butanol extraction of stationary liquid cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364151"}
{"pmid": "4364152", "title": "Studies on the degradation of poliovirus by heat.", "content": "Studies on the degradation of poliovirus by heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364152"}
{"pmid": "4364158", "title": "Demonstration of myositis ossificans by 99mTc pyrophosphate bone scanning.", "content": "Demonstration of myositis ossificans by 99mTc pyrophosphate bone scanning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364158"}
{"pmid": "4364160", "title": "Aldehyde-osmium fixation of the rat olfactory bulb: correlation between synaptic patterns and nature of the transmission.", "content": "Aldehyde-osmium fixation of the rat olfactory bulb: correlation between synaptic patterns and nature of the transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364160"}
{"pmid": "4364159", "title": "Neurosurgical aspects of leprosy.", "content": "Neurosurgical aspects of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364159"}
{"pmid": "4364161", "title": "Phosphorylation in vitro of adrenal subcellular proteins by adenosine-3',5'-monophosphate-dependent protein kinase: effect of ACTH in vivo.", "content": "Phosphorylation in vitro of adrenal subcellular proteins by adenosine-3',5'-monophosphate-dependent protein kinase: effect of ACTH in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364161"}
{"pmid": "4364162", "title": "Accentuation by angiotensin II of the antidiuretic and dipsogenic responses to intracarotid infusions of NaCl and fructose.", "content": "Accentuation by angiotensin II of the antidiuretic and dipsogenic responses to intracarotid infusions of NaCl and fructose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364162"}
{"pmid": "4364163", "title": "Hypercorticism in rabbits immunized against corticosteroids.", "content": "Hypercorticism in rabbits immunized against corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364163"}
{"pmid": "4364164", "title": "Action of cyclic adenosine 3',5' monophosphate on protein synthesis in a thyroidal cell-free system. Relation to ATP and GTP.", "content": "Action of cyclic adenosine 3',5' monophosphate on protein synthesis in a thyroidal cell-free system. Relation to ATP and GTP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364164"}
{"pmid": "4364166", "title": "Gastric localization of endodermal sinus tumour.", "content": "Gastric localization of endodermal sinus tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364166"}
{"pmid": "4364167", "title": "The fine structure of possible carcinoma-in-situ in the seminiferous tubules in the testis of four infertile men.", "content": "The fine structure of possible carcinoma-in-situ in the seminiferous tubules in the testis of four infertile men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364167"}
{"pmid": "4364168", "title": "Ultrastructural study of heterokaryons from rous rat sarcoma cells and normal chickens cells.", "content": "Ultrastructural study of heterokaryons from rous rat sarcoma cells and normal chickens cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364168"}
{"pmid": "4364169", "title": "Intracranial tumours induced in guinea pigs with Rous sarcoma virus.", "content": "Intracranial tumours induced in guinea pigs with Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364169"}
{"pmid": "4364171", "title": "Ultrastructural changes of rat blastocysts induced by estrogen during delayed implantation.", "content": "Ultrastructural changes of rat blastocysts induced by estrogen during delayed implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364171"}
{"pmid": "4364170", "title": "Competition between p-aminophenol, p-nitrophenol, and bilirubin for glucuronidation in cultures of rat hepatoma cells and homogenates of the same cells.", "content": "Competition between p-aminophenol, p-nitrophenol, and bilirubin for glucuronidation in cultures of rat hepatoma cells and homogenates of the same cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364170"}
{"pmid": "4364172", "title": "Inhibition of vesicular stomatitis virus replication by 9-beta-D-arabinofuranosyladenine.", "content": "Inhibition of vesicular stomatitis virus replication by 9-beta-D-arabinofuranosyladenine. 9-beta-d-Arabinofuranosyladenine (Ara-A) effectively inhibited the production of infectious vesicular stomatitis virus (VSV) in MDBK cells. Furthermore, inhibition was shown to begin as early as the first 3 hr of infection. Studies employing (3)H-l-leucine indicated that Ara-A did not affect protein synthesis in uninfected cells, although it did cause a marked stimulation of protein synthesis in VSV-infected cells during the log phase of the growth cycle. Puromycin, an inhibitor of protein synthesis, was a more effective viral inhibitor than Ara-A. However, the combination of Ara-A and puromycin was less effective than puromycin alone except when present for long time periods. Short-term labeling experiments with (3)H-uridine demonstrated that Ara-A depressed ribonucleic acid (RNA) synthesis in uninfected cells, whereas periods of stimulation and depression of radioisotope incorporation occurred in infected cells. The results support the notion that Ara-A is incorporated into RNA early during viral replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364172"}
{"pmid": "4364173", "title": "Spectrophotometric method for the estimation of 6-aminopenicillanic acid.", "content": "Spectrophotometric method for the estimation of 6-aminopenicillanic acid. A simple, rapid, and sensitive method is described whereby 6-aminopenicillanic acid can be spectrophotometrically determined in the presence of penicillins and their degradation products without prior separation. d-(+)-Glucosamine is used as reagent. The effect of such parameters as pH, temperature, and time of heating on the formation of the chromophore is described. The recommended range is from 25 to 250 mug of 6-aminopenicillanic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364173"}
{"pmid": "4364176", "title": "Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in man and its significance in assessing penicillin absorption.", "content": "Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in man and its significance in assessing penicillin absorption. Penicillins can be metabolized to penicilloic acids in man, the extent being dependent on the penicillin structure. In the phenoxy penicillin series, phenoxymethyl penicillin was found to be particularly unstable, but the higher homologues were more stable. In the isoxazolyl series, oxacillin was unstable, and progressive insertion of halogen in the phenyl ring increased stability. Ampicillin and amoxycillin showed some instability, ampicillin possibly being the more stable. After intramuscular administration, carbenicillin was very stable in the body, ampicillin was fairly stable, and benzyl penicillin was unstable. It is important to take into account the penicilloic acid content of urine when estimating total absorption of a penicillin. Increased stability in the body as well as slower renal clearance can lead to high concentrations in the serum. Penicilloic acids seemed to be more slowly cleared from the body than penicillins. The liver is probably the site of inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364176"}
{"pmid": "4364174", "title": "Reversible inhibition of herpes simplex virus replication by hydroxyurea.", "content": "Reversible inhibition of herpes simplex virus replication by hydroxyurea. Hydroxyurea, at a concentration of 5 x 10(-2) M, inhibits the replication of herpes simplex deoxyribonucleic acid (DNA) in the nuclei of infected cells. As a result, the synthesis of infectious virus progeny was prevented. The presence of parental viral DNA genomes in inhibited cells led to the synthesis of the viral structural peptides. The inhibitory effect of hydroxyurea was reversible; after washing the cells free from hydroxyurea, virus progeny appeared after a lag of 3 h. Upon resumption of viral DNA replication, the content of radioactive viral structural peptides gradually increased in parallel with the increase in mature virions. It is concluded that the information for the synthesis of viral structural peptides is transcribed from the parental DNA genomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364174"}
{"pmid": "4364177", "title": "Antiviral activity of tobacco smoke condensate on encephalomyocarditis infection in mice.", "content": "Antiviral activity of tobacco smoke condensate on encephalomyocarditis infection in mice. A water-soluble nontumorigenic acidic fraction of tobacco smoke condensate of cigarettes has been found to have antiviral activity against encephalomyocarditis (EMC) virus infection in mice. The portion of lower molecular weight was inhibitory to the growth of EMC virus, vesicular stomatitis virus, reovirus type 2, vaccinia virus, and poliovirus type 2, but not against adenovirus type 12, in KB cell cultures. The cigarette smoke agent did not induce serum interferon although it protected mice from EMC disease by pretreatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364177"}
{"pmid": "4364175", "title": "Trial of the antiviral action of isoprinosine against rhinovirus infection of volunteers.", "content": "Trial of the antiviral action of isoprinosine against rhinovirus infection of volunteers. Isoprinosine (NPT-10381) was given orally to a group of 22 volunteers at a daily dose of 6 g for 7 days; a control group of 23 volunteers received placebo. Volunteers were inoculated intranasally with both rhinovirus type 9 and rhinovirus type 31, and the clinical picture, extent of virus shedding, and serological responses were assessed. There was no evidence that the compound had useful antiviral activity under the conditions of this trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364175"}
{"pmid": "4364178", "title": "N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl) propanediamine: antiviral activity and interferon stimulation in mice.", "content": "N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl) propanediamine: antiviral activity and interferon stimulation in mice. CP-20,961, N,N-dioctadecyl-N', N'-bis(2-hydroxyethyl)propanediamine, is an antiviral drug with low acute toxicity in mice. Parenteral injection of this compound protected mice against lethal infections with encephalomyocarditis and Semliki Forest viruses and effectively suppressed pox formation by vaccinia infection. Maximal antiviral effects were observed when CP-20,961 was administered 6 to 12 h before infection. An interferon detected in plasma 12 to 20 h after the drug was given appeared to mediate these effects. Comparison of the minimal effective and lethal doses in mice established a therapeutic index of 300.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364178"}
{"pmid": "4364179", "title": "Synergism of polymyxin and sulfonamides in L-forms of Staphylococcus aureus and Proteus mirabilis.", "content": "Synergism of polymyxin and sulfonamides in L-forms of Staphylococcus aureus and Proteus mirabilis. Earlier workers suggested that synergism of polymyxin and sulfonamides occurred because sulfonamides produced changes in the cell wall which permitted the more ready access of polymyxin. We tested this hypothesis by using L-forms, which lack cell wall. The demonstration that synergism of polymyxin and sulfonamides occurs in L-forms of Proteus mirabilis and Staphylococcus aureus suggested that the synergism is a result of some mechanism other than alterations of the cell wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364179"}
{"pmid": "4364181", "title": "Interaction of poliovirus-specific RNAs with HeLa cells and E. coli.", "content": "Interaction of poliovirus-specific RNAs with HeLa cells and E. coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364181"}
{"pmid": "4364180", "title": "Double-stranded ribonucleic acid from Mengo virus: production, characterization, and interferon-inducing and antiviral activities in comparison with polyriboinosinic-polyribocytidylic acid.", "content": "Double-stranded ribonucleic acid from Mengo virus: production, characterization, and interferon-inducing and antiviral activities in comparison with polyriboinosinic-polyribocytidylic acid. Mengo virus double-stranded ribonucleic acid (dsRNA) was obtained on a semi-industrial scale from infected cultures of BHK-21 cells grown in suspension. Yield of the extraction and purification operations was small (about 22 mg from 10(11) cells in a 100-liter culture). Physicochemical characterization of this dsRNA gave an estimated molecular weight close to 4 x 10(6), a density of 1.59 (similar to that of the poliovirus dsRNA), and a thermal transition midpoint of 94 C. This product was a little more toxic for the mouse, by the intravenous route, than polyriboinosinic . polyribocytidylic acid (poly I:C) and strictly comparable in this respect to poliovirus dsRNA. The interferon-inducing capacity in the mouse and the antiviral activities in the mouse (infected with encephalomyocarditis, Semliki Forest, influenza, foot-and-mouth disease, and murine hepatitis viruses) and in the rabbit (Shope fibroma virus) of the ultraviolet light-inactivated product were practically identical, on a quantitative basis, with those of poly I:C. In vitro and in vivo experiments showed the dsRNA from Mengo virus to be slightly but significantly more resistant than poly I:C to the inactivating effect of human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364180"}
{"pmid": "4364182", "title": "The SV40 \"S\" antigen and other papovavirus-induced surface antigens.", "content": "The SV40 \"S\" antigen and other papovavirus-induced surface antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364182"}
{"pmid": "4364183", "title": "Alterations in bovine endothelial histidine decarboxylase activity following exposure to shearing stresses.", "content": "Alterations in bovine endothelial histidine decarboxylase activity following exposure to shearing stresses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364183"}
{"pmid": "4364184", "title": "Alcoholic steatonecrosis. II. Prospective study of prevalence of Mallory bodies in biopsy speciemens and comparison of severity of hepatic disease in patients with and without this histological feature.", "content": "Alcoholic steatonecrosis. II. Prospective study of prevalence of Mallory bodies in biopsy speciemens and comparison of severity of hepatic disease in patients with and without this histological feature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364184"}
{"pmid": "4364186", "title": "Endoscopic localization of a duodenal wall tumor in Zollinger-Ellison syndrome.", "content": "Endoscopic localization of a duodenal wall tumor in Zollinger-Ellison syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364186"}
{"pmid": "4364185", "title": "Implications of portal hepatotrophic factors in hepatology.", "content": "Implications of portal hepatotrophic factors in hepatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364185"}
{"pmid": "4364187", "title": "Possible involvement of cyclic AMP in regulation of masculine sexual behaviour by testosterone.", "content": "Possible involvement of cyclic AMP in regulation of masculine sexual behaviour by testosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364187"}
{"pmid": "4364188", "title": "Proceedings: Effect of synthetic corticotrophin analogues on plasma delta4-androstenedione, testosterone and gonadotrophins in normal men.", "content": "Proceedings: Effect of synthetic corticotrophin analogues on plasma delta4-androstenedione, testosterone and gonadotrophins in normal men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364188"}
{"pmid": "4364189", "title": "Proceedings: Cytoplasmic steroid hormone 'receptors' in reproductive organs.", "content": "Proceedings: Cytoplasmic steroid hormone 'receptors' in reproductive organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364189"}
{"pmid": "4364192", "title": "Plasma testosterone, androstenedione and urinary 17-oxosteroids in hirsutism.", "content": "Plasma testosterone, androstenedione and urinary 17-oxosteroids in hirsutism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364192"}
{"pmid": "4364190", "title": "Proceedings: Effects of prostaglandin E1 and an endogenous inhibitor of vasopressin action on the cyclic AMP system in toad bladders.", "content": "Proceedings: Effects of prostaglandin E1 and an endogenous inhibitor of vasopressin action on the cyclic AMP system in toad bladders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364190"}
{"pmid": "4364191", "title": "Proceedings: The influence of the oestrous cycle upon the energy supply for angiotensin-induced contractions of rat uterus and colon.", "content": "Proceedings: The influence of the oestrous cycle upon the energy supply for angiotensin-induced contractions of rat uterus and colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364191"}
{"pmid": "4364194", "title": "Proceedings: Corticosterone in the control of corticotrophin secretion in the rat.", "content": "Proceedings: Corticosterone in the control of corticotrophin secretion in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364194"}
{"pmid": "4364193", "title": "Proceedings: Pituitary-adrenocortical function in the reserpine-treated rat.", "content": "Proceedings: Pituitary-adrenocortical function in the reserpine-treated rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364193"}
{"pmid": "4364195", "title": "Inhibition of formation of birefringent crystals by high humidity in citrus red mites infected with virus.", "content": "Inhibition of formation of birefringent crystals by high humidity in citrus red mites infected with virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364195"}
{"pmid": "4364196", "title": "The development of spindle inclusions of Choristoneura fumiferana (Lepidoptera: Tortricidae) infected with entomopox virus.", "content": "The development of spindle inclusions of Choristoneura fumiferana (Lepidoptera: Tortricidae) infected with entomopox virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364196"}
{"pmid": "4364197", "title": "67Ga-citrate imaging in untreated primary lung cancer: preliminary report of Cooperative Group.", "content": "67Ga-citrate imaging in untreated primary lung cancer: preliminary report of Cooperative Group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364197"}
{"pmid": "4364198", "title": "Tumor uptake of 99mTc-polyphosphate: its similarity with 87mSr-citrate and dissimilarity with 67Ga-citrate.", "content": "Tumor uptake of 99mTc-polyphosphate: its similarity with 87mSr-citrate and dissimilarity with 67Ga-citrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364198"}
{"pmid": "4364199", "title": "Modification of intestinal stimulatory effects of 5-hydroxytryptamine by adrenergic amines, prostaglandin E1 and theophylline.", "content": "Modification of intestinal stimulatory effects of 5-hydroxytryptamine by adrenergic amines, prostaglandin E1 and theophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364199"}
{"pmid": "4364200", "title": "Effects of verapamil on the short-circuit current of an epithelial membrane: the toad urinary bladder.", "content": "Effects of verapamil on the short-circuit current of an epithelial membrane: the toad urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364200"}
{"pmid": "4364204", "title": "Lipid composition of rat superior cervical ganglion.", "content": "Lipid composition of rat superior cervical ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364204"}
{"pmid": "4364205", "title": "In vitro desaturation of 1-14C linoleic acid in Novikoff hepatoma.", "content": "In vitro desaturation of 1-14C linoleic acid in Novikoff hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364205"}
{"pmid": "4364208", "title": "Fluorocarbon emulsion as a blood substitute: cerebral microcirculation and related parameters.", "content": "Fluorocarbon emulsion as a blood substitute: cerebral microcirculation and related parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364208"}
{"pmid": "4364210", "title": "Immunologic competence of the immature human fetus. Morphologic evidence from intrauterine Cytomegalovirus infection.", "content": "Immunologic competence of the immature human fetus. Morphologic evidence from intrauterine Cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364210"}
{"pmid": "4364209", "title": "Recurrent herpes genitalis. Treatment with Mycobacterium bovis (BCG).", "content": "Recurrent herpes genitalis. Treatment with Mycobacterium bovis (BCG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364209"}
{"pmid": "4364211", "title": "The nature of pressor responsiveness to angiotensin II in human pregnancy.", "content": "The nature of pressor responsiveness to angiotensin II in human pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364211"}
{"pmid": "4364213", "title": "Adenoid cystic carcinoma of the uterine cervix.", "content": "Adenoid cystic carcinoma of the uterine cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364213"}
{"pmid": "4364212", "title": "Relation of type 2 Herpesvirus antibodies to cervical neoplasia. Barbados, West Indies, 1971.", "content": "Relation of type 2 Herpesvirus antibodies to cervical neoplasia. Barbados, West Indies, 1971.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364212"}
{"pmid": "4364214", "title": "Hypercalcemia associated with chronic renal failure: a unifying hypothesis.", "content": "Hypercalcemia associated with chronic renal failure: a unifying hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364214"}
{"pmid": "4364215", "title": "Influence of anti-inflammatory drugs on the electroencephalographic effect of morphine in rabbits.", "content": "Influence of anti-inflammatory drugs on the electroencephalographic effect of morphine in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364215"}
{"pmid": "4364207", "title": "Influence of citrate ions on the dissolution of silica from asbestos.", "content": "Influence of citrate ions on the dissolution of silica from asbestos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364207"}
{"pmid": "4364206", "title": "Interrelation between silicosis and lung cancer. Preliminary report.", "content": "Interrelation between silicosis and lung cancer. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364206"}
{"pmid": "4364220", "title": "Development of the capillitium in Perichaena vermicularis, a plasmodial slime mold.", "content": "Development of the capillitium in Perichaena vermicularis, a plasmodial slime mold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364220"}
{"pmid": "4364221", "title": "A possible virus infection in the brown alga Pylaiella littoralis.", "content": "A possible virus infection in the brown alga Pylaiella littoralis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364221"}
{"pmid": "4364223", "title": "Clinical and polygraphic study of the cataplectic attacks.", "content": "Clinical and polygraphic study of the cataplectic attacks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364223"}
{"pmid": "4364224", "title": "ACTH therapy in some nonhypsarrhythmic forms of epilepsy.", "content": "ACTH therapy in some nonhypsarrhythmic forms of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364224"}
{"pmid": "4364225", "title": "Measurement of a progestational and antiandrogenic compound by a competitive protein binding assay.", "content": "Measurement of a progestational and antiandrogenic compound by a competitive protein binding assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364225"}
{"pmid": "4364227", "title": "Histochemical data on the parotid glands of the marmosets, Callithrix jacchus and Callithrix penicillata.", "content": "Histochemical data on the parotid glands of the marmosets, Callithrix jacchus and Callithrix penicillata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364227"}
{"pmid": "4364229", "title": "Ulastructural modifications in the keratinization process of the intermediate-layer cells in the epidermis of Natrix natrix (L.).", "content": "Ulastructural modifications in the keratinization process of the intermediate-layer cells in the epidermis of Natrix natrix (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364229"}
{"pmid": "4364228", "title": "Histochemical observations on the seminiferous epithelium of the snake testis.", "content": "Histochemical observations on the seminiferous epithelium of the snake testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364228"}
{"pmid": "4364230", "title": "Crystalloid material in marrow macrophages of specific pathogen-free mice.", "content": "Crystalloid material in marrow macrophages of specific pathogen-free mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364230"}
{"pmid": "4364231", "title": "Cytoplasmic microfilaments in the anterior lobe of the human pituitary gland.", "content": "Cytoplasmic microfilaments in the anterior lobe of the human pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364231"}
{"pmid": "4364233", "title": "Canine mycoplasmas II: biochemical characterization and serological identification.", "content": "Canine mycoplasmas II: biochemical characterization and serological identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364233"}
{"pmid": "4364232", "title": "Effect of some chemical mutagens on proteolytic activity in Lactobacilli.", "content": "Effect of some chemical mutagens on proteolytic activity in Lactobacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364232"}
{"pmid": "4364234", "title": "Rapid diagnosis by immunofluorescence of viral infections associated with the croup syndrome in children.", "content": "Rapid diagnosis by immunofluorescence of viral infections associated with the croup syndrome in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364234"}
{"pmid": "4364235", "title": "Letter: Cyclic GMP and gastric acid secretion.", "content": "Letter: Cyclic GMP and gastric acid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364235"}
{"pmid": "4364236", "title": "Are cyclic AMP effects related to real physiological phenomena?", "content": "Are cyclic AMP effects related to real physiological phenomena?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364236"}
{"pmid": "4364238", "title": "Abnormally high rate of cyclic AMP excretion from an Escherichia coli mutant deficient in cyclic AMP receptor protein.", "content": "Abnormally high rate of cyclic AMP excretion from an Escherichia coli mutant deficient in cyclic AMP receptor protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364238"}
{"pmid": "4364237", "title": "Content of 3',5' cyclic AMP and cyclic AMP phosphodiesterase in dormant and activated tissues of Jerusalem artichoke tubers.", "content": "Content of 3',5' cyclic AMP and cyclic AMP phosphodiesterase in dormant and activated tissues of Jerusalem artichoke tubers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364237"}
{"pmid": "4364239", "title": "Adenosine 3',5'-monophosphate-dependent protein kinase and amylase secretion from rat parotid gland.", "content": "Adenosine 3',5'-monophosphate-dependent protein kinase and amylase secretion from rat parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364239"}
{"pmid": "4364240", "title": "Regulation of prostaglandin metabolism: inhibition of 15-hydroxyprostaglandin dehydrogenase by thyroid hormones.", "content": "Regulation of prostaglandin metabolism: inhibition of 15-hydroxyprostaglandin dehydrogenase by thyroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364240"}
{"pmid": "4364241", "title": "Venom exonuclease (phosphodiesterase) immobilized on concanavalin-A-sepharose.", "content": "Venom exonuclease (phosphodiesterase) immobilized on concanavalin-A-sepharose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364241"}
{"pmid": "4364242", "title": "Glucocorticoid tight binding in rat liver and thymus particles.", "content": "Glucocorticoid tight binding in rat liver and thymus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364242"}
{"pmid": "4364245", "title": "On the relationship between Lp(a) lipoprotein, \"sinking pre-beta-lipoprotein\" and inherited hyper-beta-lipoproteinaemia.", "content": "On the relationship between Lp(a) lipoprotein, \"sinking pre-beta-lipoprotein\" and inherited hyper-beta-lipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364245"}
{"pmid": "4364246", "title": "Antimicrobial therapy in experimental pseudomonas infection. II.", "content": "Antimicrobial therapy in experimental pseudomonas infection. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364246"}
{"pmid": "4364248", "title": "Enzyme and enzyme fragments purification by specific immunoadsorbents. Application to structural studies of aspartokinase I-homoserine dehydrogenase I of Escherichia coli.", "content": "Enzyme and enzyme fragments purification by specific immunoadsorbents. Application to structural studies of aspartokinase I-homoserine dehydrogenase I of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364248"}
{"pmid": "4364247", "title": "Thyrotropin-binding properties of isolated thyroid cells and their purified plasma membranes. Relation of thyrotropin-specific binding to adenylate-cyclase activation.", "content": "Thyrotropin-binding properties of isolated thyroid cells and their purified plasma membranes. Relation of thyrotropin-specific binding to adenylate-cyclase activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364247"}
{"pmid": "4364249", "title": "A study of the density pattern of ATPase and respiratory enzymes during mitochondrial biogenesis of Saccharomyces cerevisiae.", "content": "A study of the density pattern of ATPase and respiratory enzymes during mitochondrial biogenesis of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364249"}
{"pmid": "4364250", "title": "Isolation and properties of hydroxycinnamate: CoA ligase from lignifying tissue of Forsythia.", "content": "Isolation and properties of hydroxycinnamate: CoA ligase from lignifying tissue of Forsythia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364250"}
{"pmid": "4364251", "title": "Properties of soluble and bound protein kinases isolated from swine kidney.", "content": "Properties of soluble and bound protein kinases isolated from swine kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364251"}
{"pmid": "4364252", "title": "Metabolism of isolated kidney tubules. Regulation of pyruvate dehydrogenase by metabolic substrates.", "content": "Metabolism of isolated kidney tubules. Regulation of pyruvate dehydrogenase by metabolic substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364252"}
{"pmid": "4364253", "title": "Template specificity of eucaryotic DNA-dependent RNA polymerases. Effect of DNA structure and integrity.", "content": "Template specificity of eucaryotic DNA-dependent RNA polymerases. Effect of DNA structure and integrity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364253"}
{"pmid": "4364255", "title": "Multilayering of the capillary basal lamina in the granular cell tumor. A marker of cellular injury.", "content": "Multilayering of the capillary basal lamina in the granular cell tumor. A marker of cellular injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364255"}
{"pmid": "4364256", "title": "Herpetic esophagitis. A common cause of esophageal ulceration.", "content": "Herpetic esophagitis. A common cause of esophageal ulceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364256"}
{"pmid": "4364257", "title": "Testing for drugs. II. Techniques and issues.", "content": "Testing for drugs. II. Techniques and issues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364257"}
{"pmid": "4364258", "title": "Some international differences in histology and survival in breast cancer.", "content": "Some international differences in histology and survival in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364258"}
{"pmid": "4364259", "title": "Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to superinfection and the inducibility of the resident viral genome.", "content": "Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to superinfection and the inducibility of the resident viral genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364259"}
{"pmid": "4364260", "title": "Histologic characteristics of breast cancer in Boston and Tokyo.", "content": "Histologic characteristics of breast cancer in Boston and Tokyo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364260"}
{"pmid": "4364261", "title": "Oncogenic activity of N-nitrosododecamethyleneimine in liver, glandular stomach and other tissues of NZO-B1 mice.", "content": "Oncogenic activity of N-nitrosododecamethyleneimine in liver, glandular stomach and other tissues of NZO-B1 mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364261"}
{"pmid": "4364262", "title": "Temperature-dependent alterations in 2-deoxyglucose uptake in rat cells transformed by a cold-sensitive murine sarcoma virus mutant.", "content": "Temperature-dependent alterations in 2-deoxyglucose uptake in rat cells transformed by a cold-sensitive murine sarcoma virus mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364262"}
{"pmid": "4364263", "title": "Fractionation of plasma membrane-associated tumor-specific antigen from an aminoazo dye-induced rat hepatoma.", "content": "Fractionation of plasma membrane-associated tumor-specific antigen from an aminoazo dye-induced rat hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364263"}
{"pmid": "4364265", "title": "Immunological studies on a case of recurrent Burkitt's lymphoma during immune stimulant treatment.", "content": "Immunological studies on a case of recurrent Burkitt's lymphoma during immune stimulant treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364265"}
{"pmid": "4364264", "title": "Distribution of basic azo-dye-binding protein in normal rat tissues and carcinogen-induced liver tumors.", "content": "Distribution of basic azo-dye-binding protein in normal rat tissues and carcinogen-induced liver tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364264"}
{"pmid": "4364266", "title": "Isolation and characterization of a primate sarcoma virus: mechanism of rescue.", "content": "Isolation and characterization of a primate sarcoma virus: mechanism of rescue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364266"}
{"pmid": "4364267", "title": "Reversion in hybrids between SV40-transformed hamster and mouse cells.", "content": "Reversion in hybrids between SV40-transformed hamster and mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364267"}
{"pmid": "4364269", "title": "Aggregation of feline lymphoma cells by hyaluronic acid.", "content": "Aggregation of feline lymphoma cells by hyaluronic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364269"}
{"pmid": "4364270", "title": "Cell-mediated immunity and blocking factors in patients with tumours of the central nervous system.", "content": "Cell-mediated immunity and blocking factors in patients with tumours of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364270"}
{"pmid": "4364268", "title": "The horizontal development of cell-mediated tumor-specific immunity in Rous sarcoma virus tumorigenesis in rats.", "content": "The horizontal development of cell-mediated tumor-specific immunity in Rous sarcoma virus tumorigenesis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364268"}
{"pmid": "4364272", "title": "Cell-mediated immunity to human oral leukoplakia demonstrated by the leukocyte migration test.", "content": "Cell-mediated immunity to human oral leukoplakia demonstrated by the leukocyte migration test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364272"}
{"pmid": "4364274", "title": "Congenital non-progressive peripheral neuropathy with arthrogryposis multiplex.", "content": "Congenital non-progressive peripheral neuropathy with arthrogryposis multiplex. A family is described in which a hereditary peripheral neuropathy occurs, inherited as an autosomal dominant character. The syndrome is present at birth and does not show any significant progression thereafter. Three of the cases have suffered from arthrogryposis multiplex congenita. A secondary myopathy is also present. The condition appears to be intermediary between peroneal muscular atrophy and Friedreich's ataxia. Appearance at birth, presence of arthrogryposis multiplex congenita, and the non-progressive nature separate it sharply from the other heredofamilial ataxias and peripheral neuropathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364274"}
{"pmid": "4364275", "title": "Acidophilic adenoma of the pituitary with polyneuropathy.", "content": "Acidophilic adenoma of the pituitary with polyneuropathy. An acromegalic man aged 70 developed progressive polyneuropathy affecting mainly the extremities. The peripheral nerves showed hypertrophic neuropathy and accumulation of acid mucopolysaccharides in the nerve without `onion bulb' formation. The myelin showed a lamellar disintegration and vesicular formation. It is suggested that the association of these findings represents a pathological entity, acromegalic polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364275"}
{"pmid": "4364277", "title": "In vivo lipogenesis and enzyme levels in adipose and liver tissues from pair-fed genetically obese and lean rats.", "content": "In vivo lipogenesis and enzyme levels in adipose and liver tissues from pair-fed genetically obese and lean rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364277"}
{"pmid": "4364276", "title": "Electrophysiological studies of peripheral nerves in patients with organic mercury poisoning.", "content": "Electrophysiological studies of peripheral nerves in patients with organic mercury poisoning. Nineteen patients with organic mercury poisoning were examined clinically and electrophysiological studies were carried out on their peripheral nerves. Four severely affected patients were disorientated, restless, and unable to speak. Vision was abnormal in nearly half the patients, usually consisting of gross constriction of visual fields with preservation of central acuity. Severe cerebellar abnormalities were present in most. Paraesthesiae were common. On sensory examination, all except three patients had one or more of the following abnormalities: reduced appreciation of pin prick peripherally, defective position sensation, abnormal two-point discrimination, astereognosis. Vibration sensation was normal in all. Despite these sensory findings no electrophysiological abnormality was demonstrated in the peripheral nerves. It is suggested that the sensory disturbances are predominantly or entirely due to damage to the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364276"}
{"pmid": "4364278", "title": "The inhibition of L-3-hydroxyacyl-CoA dehydrogenase by acetoacetyl-CoA and the possible effect of this inhibitor on fatty acid oxidation.", "content": "The inhibition of L-3-hydroxyacyl-CoA dehydrogenase by acetoacetyl-CoA and the possible effect of this inhibitor on fatty acid oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364278"}
{"pmid": "4364279", "title": "The influence of caffeine on d-amphetamine- and apomorphine-induced stereotyped behavior.", "content": "The influence of caffeine on d-amphetamine- and apomorphine-induced stereotyped behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364279"}
{"pmid": "4364280", "title": "Metabolism of prostaglandin A. I. The kidney cortex as a major site of PGA2 degradation.", "content": "Metabolism of prostaglandin A. I. The kidney cortex as a major site of PGA2 degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364280"}
{"pmid": "4364281", "title": "Rate of inactivation of adenyl cyclase and phosphodiesterase: determinants of brain cyclic AMP.", "content": "Rate of inactivation of adenyl cyclase and phosphodiesterase: determinants of brain cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364281"}
{"pmid": "4364273", "title": "Effects of hypothyroidism and hyperthyroidism on dipyrone metabolism in man.", "content": "Effects of hypothyroidism and hyperthyroidism on dipyrone metabolism in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364273"}
{"pmid": "4364287", "title": "Letter: Adenovirus type 19 keratoconjunctivitis.", "content": "Letter: Adenovirus type 19 keratoconjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364287"}
{"pmid": "4364286", "title": "BCG and cancer (first of two parts).", "content": "BCG and cancer (first of two parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364286"}
{"pmid": "4364292", "title": "Lipid biosynthesis.", "content": "Lipid biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364292"}
{"pmid": "4364298", "title": "Functional parameters in the study of metabolic regulation.", "content": "Functional parameters in the study of metabolic regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364298"}
{"pmid": "4364299", "title": "Effect of beta receptor blockade on liver injury induced by carbon tetrachloride.", "content": "Effect of beta receptor blockade on liver injury induced by carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364299"}
{"pmid": "4364303", "title": "Letter: Femoral neuropathy.", "content": "Letter: Femoral neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364303"}
{"pmid": "4364290", "title": "Sleep-waking patterns and brain biogenic amine levels in cats after administration of 6-hydroxydopamine into the dorsolateral pontine tegmentum.", "content": "Sleep-waking patterns and brain biogenic amine levels in cats after administration of 6-hydroxydopamine into the dorsolateral pontine tegmentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364290"}
{"pmid": "4364304", "title": "Roentgenography of the ear and eye in Pyle disease.", "content": "Roentgenography of the ear and eye in Pyle disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364304"}
{"pmid": "4364306", "title": "Letter: Bile duct adenomatosis of the liver.", "content": "Letter: Bile duct adenomatosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364306"}
{"pmid": "4364291", "title": "Elicitation of water ingestion in the Mongolian gerbil (Meriones unguiculatus) by intracranial injections of angiotensin II and 1-norepinephrine.", "content": "Elicitation of water ingestion in the Mongolian gerbil (Meriones unguiculatus) by intracranial injections of angiotensin II and 1-norepinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364291"}
{"pmid": "4364305", "title": "Idiopathic hypoglycemia in infancy. Surgical management.", "content": "Idiopathic hypoglycemia in infancy. Surgical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364305"}
{"pmid": "4364307", "title": "Theoretical view of REM sleep function: maintenance of catecholamine systems in the central nervous system.", "content": "Theoretical view of REM sleep function: maintenance of catecholamine systems in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364307"}
{"pmid": "4364289", "title": "Sleep and serotonin in two strains of Mus musculus.", "content": "Sleep and serotonin in two strains of Mus musculus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364289"}
{"pmid": "4364308", "title": "The action of D-amphetamine on spontaneous activity in the caudate nucleus and reticular formation of the rat.", "content": "The action of D-amphetamine on spontaneous activity in the caudate nucleus and reticular formation of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364308"}
{"pmid": "4364309", "title": "Family treatment within the milieu of a residential treatment center.", "content": "Family treatment within the milieu of a residential treatment center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364309"}
{"pmid": "4364300", "title": "Audiological comparison of cochlear and eighth nerve disorders.", "content": "Audiological comparison of cochlear and eighth nerve disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364300"}
{"pmid": "4364311", "title": "Proceedings: Experimental herpes arthritis--chronicity and species specificity.", "content": "Proceedings: Experimental herpes arthritis--chronicity and species specificity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364311"}
{"pmid": "4364310", "title": "An Israeli experimental group with primary school dropouts outside the school setting.", "content": "An Israeli experimental group with primary school dropouts outside the school setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364310"}
{"pmid": "4364302", "title": "Association of nerve fibers and plasma cells in abnormal human nasal respiratory mucosa.", "content": "Association of nerve fibers and plasma cells in abnormal human nasal respiratory mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364302"}
{"pmid": "4364312", "title": "Effect of phenobarbitone treatment on vitamin D metabolism in mammals.", "content": "Effect of phenobarbitone treatment on vitamin D metabolism in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364312"}
{"pmid": "4364314", "title": "Melatonin and the endocrine role of the pineal organ.", "content": "Melatonin and the endocrine role of the pineal organ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364314"}
{"pmid": "4364313", "title": "Investigation of serum lipoproteins and apoproteins in abetalipoproteinaemia.", "content": "Investigation of serum lipoproteins and apoproteins in abetalipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364313"}
{"pmid": "4364315", "title": "Luteinizing hormone and human chorionic gonadotropin: structure and activity.", "content": "Luteinizing hormone and human chorionic gonadotropin: structure and activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364315"}
{"pmid": "4364316", "title": "The effect of corticotrophine and cortisone on arylsulphatase activity in stomach mucosa of rats.", "content": "The effect of corticotrophine and cortisone on arylsulphatase activity in stomach mucosa of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364316"}
{"pmid": "4364301", "title": "Cochlear and neural diseases: classification and oto-audiologic correlations.", "content": "Cochlear and neural diseases: classification and oto-audiologic correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364301"}
{"pmid": "4364321", "title": "Effects of BCG on various facets of the immune response against polyoma tumors in rats.", "content": "Effects of BCG on various facets of the immune response against polyoma tumors in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364321"}
{"pmid": "4364322", "title": "EBV infections in Brazil. I. Occurrence in normal persons, in lymphomas and in leukemias.", "content": "EBV infections in Brazil. I. Occurrence in normal persons, in lymphomas and in leukemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364322"}
{"pmid": "4364323", "title": "Antibody to Epstein-Barr virus and cellular immunity in Hodgkin's disease and chronic lymphatic leukemia.", "content": "Antibody to Epstein-Barr virus and cellular immunity in Hodgkin's disease and chronic lymphatic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364323"}
{"pmid": "4364319", "title": "Comparison of blood platelet and erythrocyte lipids in man in three age groups from three regions: Milan, Cincinnati and Sicily.", "content": "Comparison of blood platelet and erythrocyte lipids in man in three age groups from three regions: Milan, Cincinnati and Sicily.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364319"}
{"pmid": "4364325", "title": "Cell locomotion and contact inhibition of normal and neoplastic rat cells.", "content": "Cell locomotion and contact inhibition of normal and neoplastic rat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364325"}
{"pmid": "4364318", "title": "Platelet lipid modifications induced by fatty acids. Experimental studies and correlations with human neuropathology.", "content": "Platelet lipid modifications induced by fatty acids. Experimental studies and correlations with human neuropathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364318"}
{"pmid": "4364324", "title": "Growth and antigenic properties of a biopsy-derived Burkitt's lymphoma in thymus-less (nude) mice.", "content": "Growth and antigenic properties of a biopsy-derived Burkitt's lymphoma in thymus-less (nude) mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364324"}
{"pmid": "4364327", "title": "Synthesis of murine leukemia virus in cell culture.", "content": "Synthesis of murine leukemia virus in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364327"}
{"pmid": "4364326", "title": "Growth regulation and tumour formation of normal and neoplastic rat cells.", "content": "Growth regulation and tumour formation of normal and neoplastic rat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364326"}
{"pmid": "4364328", "title": "Cold-sensitive mutant of Salmonella typhimurium defective in nucleosidediphosphokinase.", "content": "Cold-sensitive mutant of Salmonella typhimurium defective in nucleosidediphosphokinase. A cold-sensitive mutant of Salmonella typhimurium defective in nucleosidediphosphokinase (ATP:nucleosidediphosphate phosphotransferase, EC 2.7.4.6) has been isolated and characterized. The mutant contains only 2% of the enzyme activity found in the parent, and the heat lability of this activity is 10 times that from the parent at 33 C. Mutant extracts lack the ability to convert any of 11 nucleoside diphosphates tested to the corresponding nucleoside triphosphates, but the nucleosidemonophosphatase activities are normal. Although the nucleoside triphosphate pools of the mutant are depressed significantly at the restrictive temperature (20 C), they are slightly elevated at the permissive temperature (37 C). The levels of guanosine pentaphosphate and guanosine tetraphosphate are dramatically increased. Two representative enzymes of pyrimidine de novo synthesis, aspartic transcarbamylase and dihydroorotate dehydrogenase, are fully repressed at both 37 and 20 C. Intracellular pools of uridine diphosphate are depressed at both permissive and restrictive temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364328"}
{"pmid": "4364320", "title": "Effect of lipids and hypolipaemic drugs on platelet aggregation and thrombosis.", "content": "Effect of lipids and hypolipaemic drugs on platelet aggregation and thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364320"}
{"pmid": "4364330", "title": "Ribonucleic acid regulation in premeabilized cells of Escherichia coli capable of ribonucleic acid and protein synthesis.", "content": "Ribonucleic acid regulation in premeabilized cells of Escherichia coli capable of ribonucleic acid and protein synthesis. A cell permeabilization procedure is described that reduces viability less than 10% and does not significantly reduce the rates of ribonucleic acid and protein synthesis when appropriately supplemented. Permeabilization abolishes the normal stringent coupling of protein and ribonucleic acid synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364330"}
{"pmid": "4364331", "title": "Inhibition of transformation by sodium metaperiodate in Streptococcus sanguis (Wicky): demonstration that deoxyribonucleic acid binding sites contain amino acids.", "content": "Inhibition of transformation by sodium metaperiodate in Streptococcus sanguis (Wicky): demonstration that deoxyribonucleic acid binding sites contain amino acids. Addition of sodium metaperiodate to competent Streptococcus sanguis (Wicky) cells at 0 or 37 C revealed that the deoxyribonucleic acid binding sites consist of amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364331"}
{"pmid": "4364329", "title": "Properties of a thermosensitive asporogenous filamentous mutant of Bacillus megaterium.", "content": "Properties of a thermosensitive asporogenous filamentous mutant of Bacillus megaterium. Mutant TH14 of Bacillus megaterium ATCC 19213 is thermosensitive and defective in cell-division septation and spore formation at the restrictive temperature (39 C). As a consequence, the mutant forms multinucleate aseptate filaments and is asporogenic. The mutation does not result in any qualitative compositional changes in extractable membrane proteins. At the restrictive temperature, the mutant membrane has a reduced content of a small molecular weight protein(s). A membrane protein(s) with a molecular weight of nearly 80,000 appears to be partially derepressed in the mutant grown at the restrictive temperature. In addition, numerous unidentified spherical inclusions of fairly uniform size (diameter approximately 100 nm) are present in the cytoplasm at the restrictive temperature. They are especially concentrated at only one pole of each filament. Filamentous growth of the mutant is less sensitive to penicillin than growth in the rod form. Growth in either form is equally sensitive to d-cycloserine at the concentrations used for selection of the mutant. Temperature shift-up experiments suggest that one to two rounds of deoxyribonucleic acid (DNA) replication occur before the phenotypic expression of the mutation occurs. The septations after these replication events can be either two-division septations or a single-division septation plus a subsequent sporulation septation. This conclusion, coupled with previously reported work, supports the hypothesis that the early stages of sporulation represent a modified cell division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364329"}
{"pmid": "4364332", "title": "Characteristics and relationships of mercury-resistant mutants and methionine auxotrophs of yeast.", "content": "Characteristics and relationships of mercury-resistant mutants and methionine auxotrophs of yeast. Approximately one-half of the mutants of Saccharomyces cerevisiae that are selected as resistant to methyl mercury are also found to require methionine. Eighty-four percent of these met mutations occur at the met15 locus, and the remaining 16% occur at the met2 locus. Surprisingly, the methionine-requiring mutants are recovered at a much higher frequency on methionineless media than on media supplemented with methionine. Growth patterns of the met mutants on media having a continuous concentration gradient of methionine and mercury compounds indicate that, at a critical concentration of the mercury compounds, the methionine requirement of certain met mutants is partially or completely alleviated. This was found for met2, met15, and to a lesser extent for met6, but not for any other methionine mutants. This loss of methionine requirement is produced with methyl mercury, phenyl mercury, and mercuric chloride although met2 and met15 strains can be shown to be resistant only to methyl mercury. Other methionine auxotrophs are not resistant to any of the three mercury compounds. The met2 and met15 mutants, but not the other methionine auxotrophs, develop a sheen of an unidentified product when grown on media with mercuric chloride but not with methyl mercury or phenyl mercury. It is suggested that met2 and met15 mutants produce a simple diffusible substance, which detoxifies methyl mercury, which reacts with mercuric chloride to produce a sheen, and which is the cause of the methionine requirement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364332"}
{"pmid": "4364333", "title": "Threonine locus of Escherichia coli K-12: genetic structure and evidence for an operon.", "content": "Threonine locus of Escherichia coli K-12: genetic structure and evidence for an operon. Three genes, thrA, thrB, and thrC, were previously defined and localized in the threonine locus of Escherichia coli K-12. thrA, thrB, and thrC specify the enzymes aspartokinase I-homoserine dehydrogenase I, homoserine kinase, and threonine synthetase, respectively. A complementation analysis of the threonine cluster using derivatives of a lambda phage carrying the threonine genes (lambdadthr(c)) demonstrates that: (i) thrB and thrC each consist of a single cistron; and (ii) thrA is composed of two cistrons, thrA(1) and thrA(2), although it specifies a single polypeptide chain. thrA(1) and thrA(2) correspond to aspartokinase I and homoserine dehydrogenase I, respectively. Their relative order is established. The demonstration of polar effects of mutations (nonsense or induced by phage Mu) in thrA and thrB is taken as evidence for the existence of a thrA thrB thrC operon, transcribed in this order.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364333"}
{"pmid": "4364335", "title": "Autogenous immunity to endogenous RNA tumor virus. Identification of antibody reactivity to select viral antigens.", "content": "Autogenous immunity to endogenous RNA tumor virus. Identification of antibody reactivity to select viral antigens. The viral antigenic determinants recognized in an autogenous immune response in mice against their endogenous C-type virus have been identified by SDS-polyacrylamide gel electrophoresis of immune precipitates between various sera and H(3)-labeled intact or disrupted AKR leukemia virus. Normal B6C3F(1) [(C57BL/6 x C3H/Anf)F(1)] serum reacts with viral envelope antigens having mol wt of approximately 68,000, 43,000, and 17,000. In addition, minor reactions with viral antigens having mol wts of approximately 19,000 and 15,000 are demonstrable. The 68,000 and 43,000 mol wt antigens can be labeled with [(3)H]glucosamine and may correspond to the major viral envelope antigens M(2) and M(1), respectively. The antigens recognized by autogenous immune sera do not differ with respect to age of the animal, nor are they significantly different in sera from various strains of mice (BALB/c, C57BL/6, and C3H/Anf). These results suggest that the age-asociated and strain variations in the autogenous immune response, as determined by radioimmune precipitation assays against intact virus, are due to quantitative and qualitative alterations of antibody levels against common antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364335"}
{"pmid": "4364334", "title": "Hormonal control of lysosomal enzyme release from human neutrophils. Effects of autonomic agents on enzyme release, phagocytosis, and cylic nucleotide levels.", "content": "Hormonal control of lysosomal enzyme release from human neutrophils. Effects of autonomic agents on enzyme release, phagocytosis, and cylic nucleotide levels. The purpose of this investigation was to examine the effects of autonomic neurohormones, cyclic nucleotides, and related agents on the immunologic discharge of lysosomal enzymes from, and phagocytosis by, purified human neutrophils. In order to discern the possible intracellular mechanisms by which certain neurohormones influence neutrophil function, the concentrations of cyclic AMP and cyclic GMP in neutrophils were assessed during cell contact with phagocytizable particles and autonomic agents. The model system employed for study was the interaction of purified human neutrophils with rheumatoid arthritic (RA) serum-treated zymosan particles at 37 degrees C in a neutral, balanced salt solution containing glucose. Neutrophils ingested the particles and discharged beta-glucuronidase but not lactate dehydrogenase activity during 30 min of incubation. Treatment of zymosan particles with RA serum was more effective than treatment with normal serum with regard to the extent of both particle uptake and lysosomal enzyme release. During contact of neutrophils with RA serum-treated zymosan particles epinephrine, isoproterenol, and cyclic AMP inhibited both particle ingestion and beta-glucuronidase discharge. These actions of epinephrine were associated with a concomitant elevation of cyclic AMP levels. In contrast to the actions of catecholamines and cyclic AMP, acetylcholine and cyclic GMP accelerated lysosomal enzyme release without affecting particle uptake. The actions of acetylcholine were associated with a concomitant elevation of cyclic GMP levels. Increases in neutrophil levels of cyclic GMP but not of cyclic AMP were associated also with the discharge of beta-glucuronidase provoked by particles in the absence of added cholinergic agents. The data suggest that the immunologic release of lysosomal enzymes from human neutrophils can be regulated by autonomic neurohormones, perhaps via the selective formation of appropriate nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364334"}
{"pmid": "4364336", "title": "3-Substituted 5,7-dimethylpyrazolo(1,5-a)pyrimidines, 3',5'-cyclic-AMP phosphodiesterase inhibitors. 1.", "content": "3-Substituted 5,7-dimethylpyrazolo(1,5-a)pyrimidines, 3',5'-cyclic-AMP phosphodiesterase inhibitors. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364336"}
{"pmid": "4364337", "title": "Enzymatic isotopic assay for and presence of beta-phenylethylamine in brain.", "content": "Enzymatic isotopic assay for and presence of beta-phenylethylamine in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364337"}
{"pmid": "4364339", "title": "Isolation and partial characterization of rat brain synaptic plasma membranes.", "content": "Isolation and partial characterization of rat brain synaptic plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364339"}
{"pmid": "4364338", "title": "The lipid composition of axons from bovine brain.", "content": "The lipid composition of axons from bovine brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364338"}
{"pmid": "4364341", "title": "Mechanisms activating glycolysis in the brain in arterial hypoxia.", "content": "Mechanisms activating glycolysis in the brain in arterial hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364341"}
{"pmid": "4364342", "title": "The effect of porta-caval anastomosis upon the energy state and upon acid-base parameters of the rat brain.", "content": "The effect of porta-caval anastomosis upon the energy state and upon acid-base parameters of the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364342"}
{"pmid": "4364340", "title": "Effect of neurotransmitters on phospholipid metabolism in rat cerebral-cortex slices: cellular and subcellular distribution.", "content": "Effect of neurotransmitters on phospholipid metabolism in rat cerebral-cortex slices: cellular and subcellular distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364340"}
{"pmid": "4364343", "title": "Changes in brain alcohol dehydrogenase activity during chronic ethanol ingestion and withdrawal.", "content": "Changes in brain alcohol dehydrogenase activity during chronic ethanol ingestion and withdrawal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364343"}
{"pmid": "4364345", "title": "Effects of neonatal hyperthyroidism on activity of cyclic AMP-dependent microsomal protein kinase.", "content": "Effects of neonatal hyperthyroidism on activity of cyclic AMP-dependent microsomal protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364345"}
{"pmid": "4364344", "title": "2',3'-Cyclic AMP 3'-phosphohydrolase activity during Wallerian degeneration.", "content": "2',3'-Cyclic AMP 3'-phosphohydrolase activity during Wallerian degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364344"}
{"pmid": "4364347", "title": "The biosynthesis and concentration of galactosyl diglyceride in glial and neuronal enriched fractions of actively myelinating rat brain.", "content": "The biosynthesis and concentration of galactosyl diglyceride in glial and neuronal enriched fractions of actively myelinating rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364347"}
{"pmid": "4364346", "title": "Detergent-like action of tetraphenylborate on phospholipid labelling in guinea pig cortex subfractions.", "content": "Detergent-like action of tetraphenylborate on phospholipid labelling in guinea pig cortex subfractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364346"}
{"pmid": "4364348", "title": "Neuronal cell body enriched and glial cell enriched fractions from young and adult rat brains: preparation and morphological and biochemical properties.", "content": "Neuronal cell body enriched and glial cell enriched fractions from young and adult rat brains: preparation and morphological and biochemical properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364348"}
{"pmid": "4364349", "title": "Elevation of cyclic GMP levels in central nervous system by excitatory and inhibitory amino acids.", "content": "Elevation of cyclic GMP levels in central nervous system by excitatory and inhibitory amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364349"}
{"pmid": "4364350", "title": "In vivo changes of cerebral cyclic adenosine 3',5'-monophosphate induced by biogenic amines: association with phosphorylase activation.", "content": "In vivo changes of cerebral cyclic adenosine 3',5'-monophosphate induced by biogenic amines: association with phosphorylase activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364350"}
{"pmid": "4364352", "title": "Enzymatic acylation of histidine to mengovirus RNA.", "content": "Enzymatic acylation of histidine to mengovirus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364352"}
{"pmid": "4364351", "title": "Influence of cephalin and egg lecithin on pig heart malate dehydrogenase activity.", "content": "Influence of cephalin and egg lecithin on pig heart malate dehydrogenase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364351"}
{"pmid": "4364353", "title": "Structure of inositol hexaphosphate--human deoxyhaemoglobin complex.", "content": "Structure of inositol hexaphosphate--human deoxyhaemoglobin complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364353"}
{"pmid": "4364355", "title": "Prostaglandins and the regulation of uterine blood flow in pregnancy.", "content": "Prostaglandins and the regulation of uterine blood flow in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364355"}
{"pmid": "4364354", "title": "Expression of polyoma-induced antigens in low malignant hybrids derived from fusion of a polyoma-induced tumour with a fibroblast line.", "content": "Expression of polyoma-induced antigens in low malignant hybrids derived from fusion of a polyoma-induced tumour with a fibroblast line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364354"}
{"pmid": "4364357", "title": "Presence of HCN in chlorella vulgaris and its possible role in controlling the reduction of nitrate.", "content": "Presence of HCN in chlorella vulgaris and its possible role in controlling the reduction of nitrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364357"}
{"pmid": "4364356", "title": "Solubilisation of angiotensin II receptors in rabbit aortae membranes.", "content": "Solubilisation of angiotensin II receptors in rabbit aortae membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364356"}
{"pmid": "4364358", "title": "Class of promotor sites for Escherichia coli DNA-dependent RNA polymerase.", "content": "Class of promotor sites for Escherichia coli DNA-dependent RNA polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364358"}
{"pmid": "4364360", "title": "Cytochrome c oxidase: some current biochemical and biophysical problems.", "content": "Cytochrome c oxidase: some current biochemical and biophysical problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364360"}
{"pmid": "4364359", "title": "Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and DNA.", "content": "Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364359"}
{"pmid": "4364363", "title": "Blocking antibodies and enhancement.", "content": "Blocking antibodies and enhancement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364363"}
{"pmid": "4364362", "title": "Thyroid hormone action: in vitro demonstration of putative receptors in isolated nuclei and soluble nuclear extracts.", "content": "Thyroid hormone action: in vitro demonstration of putative receptors in isolated nuclei and soluble nuclear extracts. Saturable binding activities for triiodothyronine were demonstrated in vitro with isolated nuclei and soluble nuclear extracts of rat liver, kidney, and cultured GH(1) cells. The binding activity can be extracted from nuclei in soluble form with no significant change in hormone affinity and has properties of a nonhistone protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364362"}
{"pmid": "4364361", "title": "Latent ganglionic infection with herpes simplex virus types 1 and 2: viral reactivation in vivo after neurectomy.", "content": "Latent ganglionic infection with herpes simplex virus types 1 and 2: viral reactivation in vivo after neurectomy. Inoculation of the cornea, lip, or footpad of mice with herpes simplex virus type 1 resulted in a latent infection of the local sensory ganglia. Inoculation of the vagina and cervix with herpes simplex virus type 2, as well as type 1, also induced a latent ganglionic infection. With the use of sciatic nerve section as a stimulus, a reproducible model of viral reactivation in vivo was established.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364361"}
{"pmid": "4364364", "title": "Invasive mole, gestational choriocarcinoma and transplantation antigens.", "content": "Invasive mole, gestational choriocarcinoma and transplantation antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364364"}
{"pmid": "4364365", "title": "Phospholipid requirements in thrombin formation.", "content": "Phospholipid requirements in thrombin formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364365"}
{"pmid": "4364367", "title": "A new in vitro method for assay of the biological activity of growth hormone.", "content": "A new in vitro method for assay of the biological activity of growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364367"}
{"pmid": "4364366", "title": "Effects of hypophysectomy with or without ACTH maintenance therapy on the final steps of aldosterone biosynthesis in the rat.", "content": "Effects of hypophysectomy with or without ACTH maintenance therapy on the final steps of aldosterone biosynthesis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364366"}
{"pmid": "4364368", "title": "Serum pre-beta-1 lipoprotein fraction in coronary atherosclerosis.", "content": "Serum pre-beta-1 lipoprotein fraction in coronary atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364368"}
{"pmid": "4364369", "title": "Pre-beta-1 lipoprotein and early detection of risk factors for coronary heart disease.", "content": "Pre-beta-1 lipoprotein and early detection of risk factors for coronary heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364369"}
{"pmid": "4364371", "title": "Ribonuclease T1, Structure and function.", "content": "Ribonuclease T1, Structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364371"}
{"pmid": "4364370", "title": "Effect of bicarbonate and phosphate on the adrenergic receptor response in human adipose tissue in vitro.", "content": "Effect of bicarbonate and phosphate on the adrenergic receptor response in human adipose tissue in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364370"}
{"pmid": "4364373", "title": "Serum and liver triglycerides in malnourished Jamaican children with fatty liver.", "content": "Serum and liver triglycerides in malnourished Jamaican children with fatty liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364373"}
{"pmid": "4364372", "title": "Normal and abnormal sexual maturation.", "content": "Normal and abnormal sexual maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364372"}
{"pmid": "4364374", "title": "Papillary adenofibroma of the uterus: a benign mesodermal mixed tumor of Müllerian orgin.", "content": "Papillary adenofibroma of the uterus: a benign mesodermal mixed tumor of Müllerian orgin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364374"}
{"pmid": "4364376", "title": "Studies on amikhellin. I. Intercalative binding to double-stranded DNA.", "content": "Studies on amikhellin. I. Intercalative binding to double-stranded DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364376"}
{"pmid": "4364380", "title": "Effect of cyclic 3'-5' GMP on in vitro protein synthesis.", "content": "Effect of cyclic 3'-5' GMP on in vitro protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364380"}
{"pmid": "4364379", "title": "Properties of 3-aldoxime pyridine adenine dinucleotide, an NAD+ analogue.", "content": "Properties of 3-aldoxime pyridine adenine dinucleotide, an NAD+ analogue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364379"}
{"pmid": "4364381", "title": "Editorial: Guidelines on the analysis of tumour rates and death rates in experimental animals.", "content": "Editorial: Guidelines on the analysis of tumour rates and death rates in experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364381"}
{"pmid": "4364382", "title": "Fibrosis as in indication of time in infiltrating breast cancer and its importance in prognosis.", "content": "Fibrosis as in indication of time in infiltrating breast cancer and its importance in prognosis. The histological grading of tumours according to their intrinsic malignancy is very important in the prognosis of breast cancer but within each grade the ultimate prognosis depends mainly on the age of the tumours.We have shown that tumour fibrosis is an indication of this time factor, increasing with the age of the tumour. Within each grade the metastatic ratio is higher and the 5 year and 10 year survival less with the scirrhous than with the non-scirrhous tumours. The establishment of axillary metastases is closely connected with both the degree of malignancy and the time available, the unfavourable effect upon survival being greater in the scirrhous than in the non-scirrhous tumours.Another consequence of the passage of time, as indicated by fibrosis, is the gradual diminution of lymphoid infiltration (LI) which is mostly present in young tumours, especially those of high grades. The favourable effect of LI upon survival is demonstrated in the non-scirrhous tumours of grade III, possibly because of its great intensity, but this influence upon survival is lost as fibrosis increases and the intensity of the reaction diminishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364382"}
{"pmid": "4364385", "title": "Pulmonary blastoma.", "content": "Pulmonary blastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364385"}
{"pmid": "4364383", "title": "Survival rates of lung cancer according to histological type.", "content": "Survival rates of lung cancer according to histological type. The post-operative survival in 554 lung carcinomata, classified according to the histological type, was calculated by the actuarial method. On the whole, squamous cell carcinoma was the most favourable and anaplastic small cell carcinoma the least favourable lesion. However, in tumours smaller than 4 cm, confined to the lung and with negative lymph nodes (stage I), small cell carcinoma had the highest percentage of 5 year survivors, followed by large cell carcinoma, squamous cell carcinoma and adenocarcinoma. When tumours had attained a larger size and/or spread to neighbouring structures and regional lymph nodes (stage II and III), the histological type was a much more determining factor in survival, squamous cell carcinoma being a significantly more favourable lesion. On the other hand, no difference in survival in relation to the histological type was found when distant metastases were probably present (stage IV). It was concluded that in assessing the role of histopathology in the prognosis of lung cancer, the mutual relationship to other pathological factors must be taken into account.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364383"}
{"pmid": "4364384", "title": "The effects of the inhalation of asbestos in rats.", "content": "The effects of the inhalation of asbestos in rats. Two experiments in which SPF Wistar rats were exposed by inhalation to dust clouds of the UICC standard reference samples for periods of between one day and 2 years are described. All the samples of asbestos produced asbestosis which continued to progress after removal from exposure but only a little fibrosis was observed in control rats. Lung tumours, ranging in severity from adenomata to squamous carcinomata, were produced by all samples but in the controls there were only a few adenomata and none of the more serious tumours. Of the 20 tumours which metastasized, 16 occurred after exposure to one or other of the 2 chrysotile samples. In addition, a total of 11 mesotheliomata occurred, 4 of which were with crocidolite and 4 with Canadian chrysotile. Two of the mesotheliomata occurred with only one day's exposure to asbestos. There was a positive association between asbestosis and lung tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364384"}
{"pmid": "4364386", "title": "Management of an infected simple renal cyst by percutaneous aspiration.", "content": "Management of an infected simple renal cyst by percutaneous aspiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364386"}
{"pmid": "4364387", "title": "Characterization of the periodate oxidation of glycerol and related compounds, and application toward determination of serum triglyceride concentrations.", "content": "Characterization of the periodate oxidation of glycerol and related compounds, and application toward determination of serum triglyceride concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364387"}
{"pmid": "4364388", "title": "Plasma corticotropin radioimmunoassay, with use of fuller's earth for extraction.", "content": "Plasma corticotropin radioimmunoassay, with use of fuller's earth for extraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364388"}
{"pmid": "4364389", "title": "Diabetic neuropathic cachexia.", "content": "Diabetic neuropathic cachexia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364389"}
{"pmid": "4364392", "title": "A linear steady-state treatment of enzymatic chains. A mathematical model of glycolysis of human erythrocytes.", "content": "A linear steady-state treatment of enzymatic chains. A mathematical model of glycolysis of human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364392"}
{"pmid": "4364393", "title": "RNA ligase activity in phage-infected bacteria and animal cells.", "content": "RNA ligase activity in phage-infected bacteria and animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364393"}
{"pmid": "4364395", "title": "Kinetics of the interaction between pig-plasma benzylamine oxidase and hydrazine derivatives.", "content": "Kinetics of the interaction between pig-plasma benzylamine oxidase and hydrazine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364395"}
{"pmid": "4364399", "title": "Autoradiographic studies on the influence of ACTH and ovarian hormones on proliferation of epithelial cells of the mammary gland in white mice.", "content": "Autoradiographic studies on the influence of ACTH and ovarian hormones on proliferation of epithelial cells of the mammary gland in white mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364399"}
{"pmid": "4364394", "title": "Alteration of ribosomal proteins and functions by 2-methoxy-5-nitrotropone.", "content": "Alteration of ribosomal proteins and functions by 2-methoxy-5-nitrotropone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364394"}
{"pmid": "4364396", "title": "Affinity chromatography on immobilised adenosine 5'-monophosphate. Some kinetic parameters involved in the binding of group-specific enzymes.", "content": "Affinity chromatography on immobilised adenosine 5'-monophosphate. Some kinetic parameters involved in the binding of group-specific enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364396"}
{"pmid": "4364398", "title": "Prostaglandin induction of mitochondrial respiration and adaptive changes of enzymes in the perfused rat liver.", "content": "Prostaglandin induction of mitochondrial respiration and adaptive changes of enzymes in the perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364398"}
{"pmid": "4364397", "title": "Studies on the quaternary structure of the threonine-sensitive aspartokinase-homoserine dehydrogenase of Escherichia coli. A proposed subunit-interaction model.", "content": "Studies on the quaternary structure of the threonine-sensitive aspartokinase-homoserine dehydrogenase of Escherichia coli. A proposed subunit-interaction model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364397"}
{"pmid": "4364400", "title": "Effect of bacterial enterotoxins on the gastrointestinal tract.", "content": "Effect of bacterial enterotoxins on the gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364400"}
{"pmid": "4364402", "title": "Lipolysis in genetically obese and diabetes-prone mice.", "content": "Lipolysis in genetically obese and diabetes-prone mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364402"}
{"pmid": "4364403", "title": "Electron microscopic studies on the existence of the so called \"acinar-islet cells\" in the regenerating pancreas of the rat.", "content": "Electron microscopic studies on the existence of the so called \"acinar-islet cells\" in the regenerating pancreas of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364403"}
{"pmid": "4364405", "title": "Circadian rhythmicity of hypothalamic CRH and its central nervous regulation.", "content": "Circadian rhythmicity of hypothalamic CRH and its central nervous regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364405"}
{"pmid": "4364404", "title": "Cushing's syndrome following ectopic neoplastic production of corticotropin. (Report of 4 cases studied by clinical and biochemical methods, and by microscopic and macroscopic anatomy).", "content": "Cushing's syndrome following ectopic neoplastic production of corticotropin. (Report of 4 cases studied by clinical and biochemical methods, and by microscopic and macroscopic anatomy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364404"}
{"pmid": "4364407", "title": "Diabetes mellitus--a disorder of cellular information transmission?", "content": "Diabetes mellitus--a disorder of cellular information transmission?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364407"}
{"pmid": "4364406", "title": "Potentiation by antidiuretic hormone (vasopressin) of the ability of parathyroid hormone to stimulate the proliferation of rat thymic lymphocytes.", "content": "Potentiation by antidiuretic hormone (vasopressin) of the ability of parathyroid hormone to stimulate the proliferation of rat thymic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364406"}
{"pmid": "4364410", "title": "Immunochemical localization of parathyroid hormone in cancer tissue from patients with ectopic hyperparathyroidism.", "content": "Immunochemical localization of parathyroid hormone in cancer tissue from patients with ectopic hyperparathyroidism. Immunoreactive parathyroid hormone (PTH) in nonparathyroid malignant tumors associated with hypercalcemia and hypophosphatemia in the absence of demonstrable bone metastases was determined by radioimmunoassay and immunofluorescent techniques. Six of seven tumors contained material with immunological cross-reactivity to bovine PTH by radioimmunoassay and immunofluorescence. The intensity of the immunofluorescent stain varied considerably in the different tumors. From 15 to 90% of neoplastic cells were stained specifically with fluorescein-labeled anti-PTH. In contrast, normal parathyroid glands and parathyroid adenomas showed uniform distribution of immunofluorescence in all parenchymal cells. In one malignant tumor, PTH was localized also by immunoautoradiography. In every case PTH was detected only in the cytoplasm of parenchymal cells. One patient lacked detectable PTH in his tumor, yet showed regression of the hypercalcemia to normal values after removal of large masses of neoplastic tissue and recurrence of hypercalcemia when new growth occurred.Dilutional radioimmunoassay curves of nonparathyroid malignant tumors were in most cases different from those obtained with extracts of normal parathyroid glands and parathyroid adenomas. Although both nonparathyroid neoplasmas and parathyroid extracts demonstrated immunoheterogeneity by gel filtration, greater heterogeneity was found in nonparathyroid malignant tumors. In those tumors in which immunological cross-reactivity to PTH was detected, the capability of secreting PTH may be restricted to derepressed cell clones amidst other neoplastic cells, whereas the greater heterogeneity of ectopic PTH may reflect hormone cleavage by proteolytic enzymes in the tumor that is less specific than the Pro-PTH cleaving enzyme in the parathyroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364410"}
{"pmid": "4364411", "title": "The effect of ethidium bromide on the membrane glycopeptides in control and virus-transformed cells.", "content": "The effect of ethidium bromide on the membrane glycopeptides in control and virus-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364411"}
{"pmid": "4364412", "title": "The effect of parathyroid hormone and thyrocalcitonin on the accumulation of cyclic adenosine 3':5'-monophosphate in freshly isolated bone cells.", "content": "The effect of parathyroid hormone and thyrocalcitonin on the accumulation of cyclic adenosine 3':5'-monophosphate in freshly isolated bone cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364412"}
{"pmid": "4364409", "title": "Biological defense mechanisms. The effect of bacteria and serum on superoxide production by granulocytes.", "content": "Biological defense mechanisms. The effect of bacteria and serum on superoxide production by granulocytes. We previously reported that granulocytes are able to produce superoxide (O(2) (-)), a highly reactive compound formed by the one-electron reduction of oxygen. The demonstration of O(2) (-) production was based on the observation that the reduction of extra-cellular cytochrome c by granulocytes was greatly diminished by superoxide dismutase, an enzyme catalyzing the conversion of O(2) (-) to hydrogen peroxide and oxygen. In the present report, studies concerning the effect of bacteria and serum on O(2) (-)-dependent cytochrome c reduction by granulocytes are described.In the absence of bacteria, the O(2) (-)-dependent reduction of extracellular cytochrome c by granulocytes under optimal assay conditions amounted to 9.2+/-2.8 SD nmol/3 x 10(6) cells/20 min. When bacteria (100 organisms/cell) were present, the O(2) (-)-dependent cytochrome c reduction under otherwise similar conditions increased by a factor of nearly four (34.5+/-9.4). There was no effect of albumin or catalase on cytochrome c reduction, and boiled dismutase had only a small effect. Omission of granulocytes or substitution of live cells by cells by cells killed by heat abolished O(2) (-)-dependent cytochrome c reduction. Bacteria killed by autoclaving were almost as effective as live bacteria in stimulating granulocyte O(2) (-) production. Measurements of particle uptake and O(2) uptake by granulocytes indicated that superoxide dismutase did not affect granulocyte metabolism nonspecifically, supporting the conclusion that the diminution of cytochrome c reduction in the presence of dismutase was due to the destruction of O(2) (-) by this enzyme. Stimulation of O(2) (-) production by bacteria was strongly dependent on the presence of serum in the incubation mixture. Serum heated to 56 degrees C for 45 min was as effective as unheated serum in stimulating O(2) (-) production in the presence of bacteria, but boiled serum had no effect. Other experiments suggested that incubation of bacteria with serum resulted in the release of a nonparticulate heat-labile substance capable of stimulating O(2) (-) production in the absence of bacteria. Certain characteristics of the O(2) (-)-dependent cytochrome c reduction by granulocytes were studied, including the dependence of this process on granulocyte, cytochrome c, and bacterial concentrations. In addition, O(2) (-)-dependent cytochrome c reduction was followed as a function of time. A constant rate was found with resting granulocytes. With bacteria the time course was more complex. A well-defined lag was followed by a fairly brief period of extremely vigorous cytochrome c reduction. During this period, the maximum rate of cytochrome c reduction exceeded the rate observed in the absence of bacteria by a factor of 12. The rate then decreased until by 40 min, it had slowed to the rate observed in the absence of bacteria. From the above results, it was concluded that the exposure of the granulocyte to bacteria plus serum initiates a process in which a defined quantity of O(2) (-) is formed in a rapid burst lasting 20-30 min. It is conceivable that the O(2) (-) generated by this process may be involved in the killing of bacteria by the granulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364409"}
{"pmid": "4364413", "title": "Receptor-binding affinities and biological activities of analogs of thyrotropin-releasing hormone in prolactin-producing pituitary cells in culture.", "content": "Receptor-binding affinities and biological activities of analogs of thyrotropin-releasing hormone in prolactin-producing pituitary cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364413"}
{"pmid": "4364408", "title": "Human platelet collagenase.", "content": "Human platelet collagenase. The presence of proteolytic enzymes such as cathepsin and elastase in platelets and the important role of collagen in platelet aggregation suggested that collagenase might be present in platelets. Epinephrine, ADP, and collagen liberate collagenase from platelets in plasma as measured by the hydrolysis of [(14)C]glycine-labeled collagen fibrils. The collagenase activity appeared in an early phase of platelet aggregation and was not a part of the release reaction. However, only 50% of the total collagenase could be liberated by the aggregating agents used. Sucrose density gradient analysis of platelet homogenates using appropriate sub-cellular markers indicated that collagenase appeared in both the granule and membrane fractions. Gel-filtered platelets failed to show collagenase activity before exposure to aggregating agents but released more collagenolytic activity than was found in platelet-rich plasma. This observation was explained by the finding that collagenolytic activity was inhibited by normal human plasma. One of the inhibitors is alpha(1)-antitrypsin as demonstrated by decreased inhibition in plasma from a patient with homozygous alpha(1)-antitrypsin deficiency. Platelet collagenase activity could also be demonstrated by its ability to decrease the viscosity of collagen solutions and to produce collagen fragments similar to those produced by other mammalian collagenases on disk gel electrophoresis. The observation that partially purified platelet collagenase could destroy the platelet-aggregating activity of collagen suggests that the enzyme might function in a negative feedback mechanism limiting thrombus formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364408"}
{"pmid": "4364414", "title": "The effects of epinephrine and prostaglandin E-1 on cyclic adenosine 3':5'-monophosphate levels in WI-38 fibroblasts.", "content": "The effects of epinephrine and prostaglandin E-1 on cyclic adenosine 3':5'-monophosphate levels in WI-38 fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364414"}
{"pmid": "4364416", "title": "Electron paramagnetic resonance studies of cobalt-copper bovine superoxide dismutase.", "content": "Electron paramagnetic resonance studies of cobalt-copper bovine superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364416"}
{"pmid": "4364415", "title": "Purification and kinetic characterization of a monovalent cation-activated glycerol dehydrogenase from Aerobacter aerogenes.", "content": "Purification and kinetic characterization of a monovalent cation-activated glycerol dehydrogenase from Aerobacter aerogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364415"}
{"pmid": "4364417", "title": "Iron, an essential component of lipoxygenase.", "content": "Iron, an essential component of lipoxygenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364417"}
{"pmid": "4364418", "title": "Magnetic resonance and kinetic studies of the mechanism of sodium and potassium ion-activated adenosine triphosphatase.", "content": "Magnetic resonance and kinetic studies of the mechanism of sodium and potassium ion-activated adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364418"}
{"pmid": "4364419", "title": "The subcellular localization of glutaminase isoenzymes in rat kidney cortex.", "content": "The subcellular localization of glutaminase isoenzymes in rat kidney cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364419"}
{"pmid": "4364420", "title": "Regulation of renal ammoniagenesis. Subcellular localization of rat kidney glutaminase isoenzymes.", "content": "Regulation of renal ammoniagenesis. Subcellular localization of rat kidney glutaminase isoenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364420"}
{"pmid": "4364421", "title": "Two nucleid acid-dependent nucleoside triphosphate phosphohydrolases from vaccinia virus. Purification and characterization.", "content": "Two nucleid acid-dependent nucleoside triphosphate phosphohydrolases from vaccinia virus. Purification and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364421"}
{"pmid": "4364422", "title": "Two nucleic acid-dependent nucleoside triphosphate phosphohydrolases from vaccinia virus. Nucleotide substrate and polynucleotide cofactor specificities.", "content": "Two nucleic acid-dependent nucleoside triphosphate phosphohydrolases from vaccinia virus. Nucleotide substrate and polynucleotide cofactor specificities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364422"}
{"pmid": "4364423", "title": "Single-stranded deoxyribonucleic acid-specific nuclease from vaccinia virus. Endonucleolytic and exonucleolytic activities.", "content": "Single-stranded deoxyribonucleic acid-specific nuclease from vaccinia virus. Endonucleolytic and exonucleolytic activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364423"}
{"pmid": "4364425", "title": "Nonessentiality of the active sulfhydryl group of rabbit muscle creatine kinase.", "content": "Nonessentiality of the active sulfhydryl group of rabbit muscle creatine kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364425"}
{"pmid": "4364424", "title": "Conformational transition in polypeptide elongation factor Tu as revealed by electron spin resonance.", "content": "Conformational transition in polypeptide elongation factor Tu as revealed by electron spin resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364424"}
{"pmid": "4364426", "title": "Photoaffinity labeling with cyclic nucleotides.", "content": "Photoaffinity labeling with cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364426"}
{"pmid": "4364429", "title": "The kidney as an endocrine organ involved in calcium homeostasis.", "content": "The kidney as an endocrine organ involved in calcium homeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364429"}
{"pmid": "4364428", "title": "Disordered divalent ion metabolism in kidney disease: comments on pathogenesis and treatment.", "content": "Disordered divalent ion metabolism in kidney disease: comments on pathogenesis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364428"}
{"pmid": "4364427", "title": "Treatment of renal osteodystrophy with calciferol (vitamin D) and related steroids.", "content": "Treatment of renal osteodystrophy with calciferol (vitamin D) and related steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364427"}
{"pmid": "4364434", "title": "Fucosylglycolipids in cells transformed by a temperature-sensitive mutant of murine sarcoma virus.", "content": "Fucosylglycolipids in cells transformed by a temperature-sensitive mutant of murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364434"}
{"pmid": "4364433", "title": "Presence of a large poly(rC) tract within the RNA of encephalomyocarditis virus.", "content": "Presence of a large poly(rC) tract within the RNA of encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364433"}
{"pmid": "4364436", "title": "Parathormone, cyclic AMP and neonatal kidneys.", "content": "Parathormone, cyclic AMP and neonatal kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364436"}
{"pmid": "4364435", "title": "Carbohydrate groups in the major glycoprotein of Rous sarcoma virus.", "content": "Carbohydrate groups in the major glycoprotein of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364435"}
{"pmid": "4364437", "title": "Regulation of cell growth by cyclic AMP.", "content": "Regulation of cell growth by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364437"}
{"pmid": "4364438", "title": "Cytomegalovirus infections in New York State.", "content": "Cytomegalovirus infections in New York State.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364438"}
{"pmid": "4364442", "title": "Positive control of transformed phenotype in hybrids between SV40-transformed and normal human cells.", "content": "Positive control of transformed phenotype in hybrids between SV40-transformed and normal human cells. Somatic cell hybrids have been obtained between SV40-transformed Lesch-Nyhan fibroblasts, which are deficient in hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and display glucose-6-phosphate dehydrogenase A (G6PD-A) activity, and late-passage HGPRT-positive W138 human embryo fibroblasts, which display G6PD-B activity. The human-human hybrid clones, which display G6PD-A and G6PD-B and heteropolymers of the two enzyme forms, have the same growth characteristic as the SV40-transformed parental cells and behave as continuous cell lines. The SV40 tumor antigen, the gene for which has been assigned to human chromosome 7, is present in all clones examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364442"}
{"pmid": "4364440", "title": "Ultrastructural and functional relationships of some human endocrine tumors.", "content": "Ultrastructural and functional relationships of some human endocrine tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364440"}
{"pmid": "4364449", "title": "On the mechanism of the enhancement by smooth muscle stimulants of the motor responses of the guinea-pig vas deferens to nerve stimulation.", "content": "On the mechanism of the enhancement by smooth muscle stimulants of the motor responses of the guinea-pig vas deferens to nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364449"}
{"pmid": "4364448", "title": "Conversion of angiotensin I in pulmonary and systemic vascular beds of children.", "content": "Conversion of angiotensin I in pulmonary and systemic vascular beds of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364448"}
{"pmid": "4364451", "title": "Differences in recruitment order and discharge pattern of motor units in the early and late flexion reflex components in man.", "content": "Differences in recruitment order and discharge pattern of motor units in the early and late flexion reflex components in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364451"}
{"pmid": "4364454", "title": "Carcinogenic response of brood sows fed aflatoxin for 28 to 30 months.", "content": "Carcinogenic response of brood sows fed aflatoxin for 28 to 30 months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364454"}
{"pmid": "4364452", "title": "The effect of dopa on the spinal cord. 8. Presynaptic and \"remote\" inhibition of transmission from Ia afferents to alpha motoneurones.", "content": "The effect of dopa on the spinal cord. 8. Presynaptic and \"remote\" inhibition of transmission from Ia afferents to alpha motoneurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364452"}
{"pmid": "4364455", "title": "Infectivity of bovine C- type (leukemia) virus for sheep and goats.", "content": "Infectivity of bovine C- type (leukemia) virus for sheep and goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364455"}
{"pmid": "4364453", "title": "Stimulation of adenosine 3,5-monophosphate formation in mast cells by 5-hydroxytryptamine and guanethidine.", "content": "Stimulation of adenosine 3,5-monophosphate formation in mast cells by 5-hydroxytryptamine and guanethidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364453"}
{"pmid": "4364456", "title": "Genital disease in dogs caused by canine herpesvirus.", "content": "Genital disease in dogs caused by canine herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364456"}
{"pmid": "4364450", "title": "Activities of rat muscle enzymes after acute exercise.", "content": "Activities of rat muscle enzymes after acute exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364450"}
{"pmid": "4364458", "title": "Lesions in nervous tissue of owl monkeys experimentally infected with herpesvirus-T.", "content": "Lesions in nervous tissue of owl monkeys experimentally infected with herpesvirus-T.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364458"}
{"pmid": "4364457", "title": "Study of the use of evoked cortical activity for clinical evaluation of spinal cord sensory transmission.", "content": "Study of the use of evoked cortical activity for clinical evaluation of spinal cord sensory transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364457"}
{"pmid": "4364459", "title": "Antigenic comparisons and serologic survey of equine adenoviruses.", "content": "Antigenic comparisons and serologic survey of equine adenoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364459"}
{"pmid": "4364460", "title": "Phagocytosis of Babesia canis by neutrophils in peripheral circulation.", "content": "Phagocytosis of Babesia canis by neutrophils in peripheral circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364460"}
{"pmid": "4364461", "title": "Reduction of mercury to the elemental state by a yeast.", "content": "Reduction of mercury to the elemental state by a yeast. A yeast of the genus Cryptococcus has been isolated from a stream and was shown to be capable of reducing mercury to the elemental state. The organism grows in Wickerham broth supplemented with high concentrations of mercury (II) chloride (180 mg of mercury per liter) and will metabolize [(14)C]glucose in this medium as do cells in the absence of mercury. Mercury was associated with the cell wall and membrane, and in vacuoles within the cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364461"}
{"pmid": "4364462", "title": "The plaque-antiserum method: an assay of virus infectivity and an experimental model of virus infection.", "content": "The plaque-antiserum method: an assay of virus infectivity and an experimental model of virus infection. Areas of cytopathic effect can be circumscribed in cell monolayers by adding antiserum to the liquid nutrient medium after adsorption of virus. This procedure represents a simple and reliable tool for the titration of virus infectivity and provides an experimental model for studying some aspects of virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364462"}
{"pmid": "4364463", "title": "Environmental factors influencing isolation of enteroviruses from polluted surface waters.", "content": "Environmental factors influencing isolation of enteroviruses from polluted surface waters. The influence of water quality upon the concentration of virus on location was assessed in field studies conducted in the Houston ship channel, Galveston Bay, and Houston waste treatment plants. Clarification of polluted surface waters was accomplished with minimal loss of virus. Virus from clarified sewage effluents and saline waters was then adsorbed and concentrated on textile and membrane filter surfaces. Direct measurements of virus from large volumes of polluted surface waters under existing field conditions were then made using the virus concentrator equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364463"}
{"pmid": "4364464", "title": "Concentration of oncogenic herpesviruses by methyl alcohol precipitation.", "content": "Concentration of oncogenic herpesviruses by methyl alcohol precipitation. Oncogenic herpesviruses, like many other viruses, can be concentrated effectively from large volumes of culture fluids by precipitation with methanol with good recovery of infectivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364464"}
{"pmid": "4364466", "title": "Electrophoretic characterization of human phosphoribosylpyrophosphate synthetase.", "content": "Electrophoretic characterization of human phosphoribosylpyrophosphate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364466"}
{"pmid": "4364465", "title": "Hepatitis B (Australia) antigen--current clinical and epidemiological concepts.", "content": "Hepatitis B (Australia) antigen--current clinical and epidemiological concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364465"}
{"pmid": "4364468", "title": "Metabolite levels reflecting changes in liver energy metabolism during the neonatal period.", "content": "Metabolite levels reflecting changes in liver energy metabolism during the neonatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364468"}
{"pmid": "4364469", "title": "Influence of asphyxia and of dexamethasone on ATP concentrations in the immature rat brain.", "content": "Influence of asphyxia and of dexamethasone on ATP concentrations in the immature rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364469"}
{"pmid": "4364467", "title": "Pyruvate carboxylase in human liver. Apparent loss of a component of catalytic activity in a form of lactic acidosis with hypoglycemia.", "content": "Pyruvate carboxylase in human liver. Apparent loss of a component of catalytic activity in a form of lactic acidosis with hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364467"}
{"pmid": "4364471", "title": "Acetylcholine sensitivity of the chick fast muscle after cross-union with the slow muscle nerve.", "content": "Acetylcholine sensitivity of the chick fast muscle after cross-union with the slow muscle nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364471"}
{"pmid": "4364472", "title": "Modulation of synaptic transmission in cat's superior colliculus by saccadic eye movements.", "content": "Modulation of synaptic transmission in cat's superior colliculus by saccadic eye movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364472"}
{"pmid": "4364470", "title": "Cytoplasmic solvent structure of single barnacle muscle cells studied by electron spin resonance.", "content": "Cytoplasmic solvent structure of single barnacle muscle cells studied by electron spin resonance. A free radical probe was introduced into single barnacle muscle cells, and its freedom of motion inferred from the spin resonance spectra. The probe reported an average local viscosity of 5-10 cp compared with 1 cp for pure water. From a comparison of the temperature dependence of the probe's tumbling rate in model aqueous systems and in the muscle we concluded that in the muscle the probe was undergoing fast exchange between sites of different mobility. Thus 10 cp must be taken as an upper limit for the viscosity of most cell water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364470"}
{"pmid": "4364474", "title": "Stimulation- and calcium-dependence of vesicle attachment sites in the presynaptic membrane: a freeze-cleave study on the lamprey spinal cord.", "content": "Stimulation- and calcium-dependence of vesicle attachment sites in the presynaptic membrane: a freeze-cleave study on the lamprey spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364474"}
{"pmid": "4364473", "title": "Common synaptic effects of pentylenetetrazol and penicillin.", "content": "Common synaptic effects of pentylenetetrazol and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364473"}
{"pmid": "4364475", "title": "Ascending monoamine-containing fiber pathways related to intracranial self-stimulation: histochemical fluorescence study.", "content": "Ascending monoamine-containing fiber pathways related to intracranial self-stimulation: histochemical fluorescence study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364475"}
{"pmid": "4364477", "title": "The action of norepinephrine in the rat hippocampus. II. Activation of the input pathway.", "content": "The action of norepinephrine in the rat hippocampus. II. Activation of the input pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364477"}
{"pmid": "4364476", "title": "The action of norepinephrine in the rat hippocampus. I. Iontophoretic studies.", "content": "The action of norepinephrine in the rat hippocampus. I. Iontophoretic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364476"}
{"pmid": "4364482", "title": "Histochemical studies on the effect of sodium fluoride on metabolism in Purkinje's cells.", "content": "Histochemical studies on the effect of sodium fluoride on metabolism in Purkinje's cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364482"}
{"pmid": "4364483", "title": "The effect of oxytocin on the oxidoreductive activity and spermatogenesis in the rabbit testicle.", "content": "The effect of oxytocin on the oxidoreductive activity and spermatogenesis in the rabbit testicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364483"}
{"pmid": "4364505", "title": "Action of Escherichia coli enterotoxin: adenylate cyclase behavior of intestinal epithelial cells in culture.", "content": "Action of Escherichia coli enterotoxin: adenylate cyclase behavior of intestinal epithelial cells in culture. Heat-labile enterotoxin preparations obtained from two enteropathogenic strains of Escherichia coli of porcine and human origin were shown to stimulate adenylate cyclase activity of human embryonic intestinal epithelial cells in culture. Comparable results were also obtained when cholera toxin was used. The degree of enzyme stimulation was proportional to the concentration of enterotoxin. Similar preparations from two strains of non-enterotoxigenic E. coli had no effect on adenylate cyclase activity. Cells exposed to enterotoxin could be washed after 1 min of contact time without altering the subsequent course of maximum adenylate cyclase activity, which was maintained for at least 18 h at 37 C. During long periods (18 h) of tissue culture incubation, the determination of adenylate cyclase activity was 200- to 300-fold more sensitive than quantitating fluid accumulation in the adult rabbit ileal loop model. Decreasing the incubation time appreciably reduced the sensitivity of the epithelial cells to enterotoxin. E. coli enterotoxin is an effective activator of nonintestinal adenylate cyclase systems. Treatment of KB and HEp-2 cell lines with enterotoxin also resulted in significant enzyme stimulation. The intestinal epithelial cell tissue culture model provides a sensitive homogenous biological system for studying the response of intestinal adenylate cyclase to enterotoxin while eliminating the numerous cellular and tissue components present in the ligated ileal loop model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364505"}
{"pmid": "4364506", "title": "Replication of Marek's disease virus in cell cultures derived from genetically resistant chickens.", "content": "Replication of Marek's disease virus in cell cultures derived from genetically resistant chickens. Various parameters of replication of Marek's disease virus (MDV) were studied in cells derived from genetically resistant (line 6) and susceptible (line 7) chickens. Cell-free and cell-associated preparations of three strains of pathogenic MDV (JM, GA, and Id-1) replicated equally well in cells of resistant and susceptible chickens. There were no demonstrable differences between the two genetic sources of cells for the chronological appearance and type of cytopathic effects and for the type of virus-induced antigens detectable by immunofluorescent and agar-gel precipitin tests. MDV propagated for about 4 weeks in cells of resistant line 6 chickens remained nonvirulent for line 6 and fully virulent for line 7 chickens. The lack of expression of genetic resistance to Marek's disease at cellular level contrasts the infection mechanisms of MDV from those of viruses associated with lymphoid leukosis in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364506"}
{"pmid": "4364508", "title": "Synthesis and biological activity of some 8-substituted seleno cyclic nucleotides and related compounds.", "content": "Synthesis and biological activity of some 8-substituted seleno cyclic nucleotides and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364508"}
{"pmid": "4364509", "title": "Synthesis of analogs of (8-isoleucine)angiotensin II with variations in position 1.", "content": "Synthesis of analogs of (8-isoleucine)angiotensin II with variations in position 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364509"}
{"pmid": "4364510", "title": "Synthesis of some trinucleoside monophosphates of biological interest.", "content": "Synthesis of some trinucleoside monophosphates of biological interest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364510"}
{"pmid": "4364511", "title": "The pathology of the human muscle spindle: effect of denervation.", "content": "The pathology of the human muscle spindle: effect of denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364511"}
{"pmid": "4364514", "title": "A thin-layer chromatographic procedure for the separation of aspirin, cocaine, caffeine, codeine, heroin, 6-monoacetyl morphine, and morphine.", "content": "A thin-layer chromatographic procedure for the separation of aspirin, cocaine, caffeine, codeine, heroin, 6-monoacetyl morphine, and morphine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364514"}
{"pmid": "4364521", "title": "Oligonucleotide photoproducts formed by photolysis of polyribobromouridylic acid.", "content": "Oligonucleotide photoproducts formed by photolysis of polyribobromouridylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364521"}
{"pmid": "4364523", "title": "The phosphorescent triplet state of some hydroxycoumarins.", "content": "The phosphorescent triplet state of some hydroxycoumarins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364523"}
{"pmid": "4364522", "title": "Photochemistry of biological molecules. IV. Gaseous products from the photolysis of alanine peptides in the solid state.", "content": "Photochemistry of biological molecules. IV. Gaseous products from the photolysis of alanine peptides in the solid state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364522"}
{"pmid": "4364524", "title": "The egg yolk very low density lipoproteins of fresh and stored shell eggs.", "content": "The egg yolk very low density lipoproteins of fresh and stored shell eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364524"}
{"pmid": "4364525", "title": "Synthesis of simian virus 40 DNA in isolated nuclei.", "content": "Synthesis of simian virus 40 DNA in isolated nuclei. Nuclei isolated from African green monkey kidney cells infected with simian virus 40 at different times after infection maintain in vitro the same temporal sequence of host and viral DNA synthesis as that seen in intact cells. The viral DNA synthesized by the nuclei of cells previously infected for 32-35 hr was characterized by centrifugation through neutral and alkaline sucrose gradients, and by isopycnic banding in a propidium iodide-cesium chloride gradient. DNA synthesis in this system is maintained for only 4-5 min. Neutral sucrose gradient analysis showed that most of the radioactivity is associated with the replicative intermediate of simian virus 40 DNA and the rest sediments at 5-7 S. Alkaline gradient analysis showed that 50-60% of the radioactivity sediments as 3-7S fragments, and the rest between 7 and 16 S. Pulsechase experiments showed that in this system 3-7S fragments do not mature into long chains. A model is presented to explain the failure of these fragments to join into long chains in this in vitro nuclear system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364525"}
{"pmid": "4364526", "title": "Genetic control of melanization: isolation and analysis of amelanotic variants from cultured melanotic melanoma cells.", "content": "Genetic control of melanization: isolation and analysis of amelanotic variants from cultured melanotic melanoma cells. MELANOMA CELLS EXPRESS A PHENOTYPE THAT IS EASY TO RECOGNIZE: the synthesis of melanin. We used this marker to isolate clones of amelanotic variants from large populations of wild-type melanotic clones. Cloudman mouse melanoma (S91, clone M-3, CCL 53.1) was chosen as the parental line because the cells are highly pigmented, grow well as clones in soft agar, and fuse readily with Sendai virus. Subclones (10(7)) of this line were screened without prior mutagenesis, and nine amelanotic variants were isolated. The mutagen ethylmethanesulfonate increased the frequency of variants by three to four orders of magnitude. Wild-type cells had both basal and melanocyte stimulating hormone-inducible tyrosinase activities. The four amelanotic variants that we have examined to date all behaved similarly: they lost basal tyrosinase (EC 1.14.18.1; monophenol monooxygenase) activity but retained melanocyte stimulating hormone-inducible activity; they contained Stage-II melanosomes but no melanized melanosomes; they exhibited growth characteristics similar to those of wild-type cells in culture but produced fewer tumors in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364526"}
{"pmid": "4364527", "title": "Octopamine- and serotonin-stimulated phosphorylation of specific protein in the abdominal ganglion of Aplysia californica.", "content": "Octopamine- and serotonin-stimulated phosphorylation of specific protein in the abdominal ganglion of Aplysia californica. Phosphorylation of a protein (or proteins) of molecular weight 120,000 in the Aplysia abdominal ganglion, as measured by incorporation of [(32)P] or [(33)P]sodium phosphate in vitro followed by separation of the phosphoproteins on sodium dodecyl sulfate-polyacrylamide gels, was specifically stimulated by incubation in the presence of the putative neurotransmitters octopamine or serotonin. The stimulatory effect of octopamine and serotonin was inhibited by phentolamine and methysergide, respectively, and was mimicked by incubation in the presence of dibutyryl cyclic AMP. Label-chase experiments indicated that the difference between control and octopamine-treated ganglia persists for several hours after removal of the drug from the incubation medium. This result suggests that neurotransmitters may produce relatively long-lasting changes in a phosphoprotein in the ganglion, perhaps in postsynaptic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364527"}
{"pmid": "4364528", "title": "Relationship of a proton gradient to the active transport of proline with membrane vesicles from Mycobacterium phlei.", "content": "Relationship of a proton gradient to the active transport of proline with membrane vesicles from Mycobacterium phlei. Electron transport particles prepared from Mycobacterium phlei were depleted of bound coupling factors by washing with water in the absence of inorganic ions. The depleted electron transport particles were void of latent ATPase activity and were capable of oxidation, but were unable to support coupled phosphorylation. Nevertheless, the depleted electron transport particles were capable of substrate-induced active transport of proline. Changes in pH in response to substrate oxidation were measured in normal and depleted electron particles with bromthymol blue. A bromthymol blue response upon substrate oxidation was not observed with depleted electron transport particles. The level of oxidative phosphorylation with succinate or NADH oxidation was not reduced in the presence of proline, and proline did not have an effect upon the proton gradients formed by the oxidation of either succinate or NADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364528"}
{"pmid": "4364530", "title": "Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA.", "content": "Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA. Explanted mouse blastocysts were microinjected in the blastocoel cavity with simian virus 40 (SV40) viral DNA. After surgical transfer to the uteri of pseudopregnant surrogate mothers, approximately 40% of the blastocysts developed to term and became healthy adults without apparent tumors at 1 year of age. Molecular hybridization tests for the presence of SV40-specific DNA sequences were conducted on DNA extracted from various organs of these animals. Between 0.5 and 13 SV40 genome equivalents per diploid mouse DNA value were found in some organs of approximately 40% of the adult survivors; this represents a substantial augmentation of the amount administered per embryo. The results are consistent with the working hypothesis that the SV40 DNA may have been integrated into the host genome; alternatively, the viral DNA may have replicated as an extrachromosomal entity or by lytic infection in a few permissive cells. Persistence of the viral DNA from preimplantation stages to adult life may thus provide a new tool for experimental investigation of vertical transmission and expression of tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364530"}
{"pmid": "4364529", "title": "Cell-free transcription of mammalian chromatin: transcription of globin messenger RNA sequences from bone-marrow chromatin with mammalian RNA polymerase.", "content": "Cell-free transcription of mammalian chromatin: transcription of globin messenger RNA sequences from bone-marrow chromatin with mammalian RNA polymerase. A mammalian cell-free transcriptional system was developed in which mammalian RNA polymerase synthesizes globin messenger RNA sequences from bone-marrow chromatin. The messenger RNA sequences are detected by measurement of the ability of the transcribed RNA to hybridize with globin complementary DNA. The globin complementary DNA is synthesized by the enzyme from avian myeloblastosis virus, RNA-directed DNA polymerase, with purified globin messenger RNA as template. The specificity of the globin complementary DNA in annealing reactions was verified by preparing DNA complementary to liver messenger RNA and showing that the globin and liver complementary DNAs are specific for their own messenger RNAs. Both DNA-dependent RNA polymerase II from sheep liver and RNA polymerase from Escherichia coli can transcribe globin messenger RNA sequences from rabbit bone-marrow chromatin; however, the mammalian enzyme appears to be more specific in that globin gene sequences represent a higher proportion of the RNA synthesized. Neither polymerase can transcribe globin messenger RNA sequences from rabbit-liver chromatin. This cell-free assay system should be useful in searching for mammalian transcriptional regulatory factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364529"}
{"pmid": "4364532", "title": "Regulation of a plant 5'(3')-ribonucleotide phosphohydrolase by cyclic nucleotides and pyrimidine, purine, and cytokinin ribosides.", "content": "Regulation of a plant 5'(3')-ribonucleotide phosphohydrolase by cyclic nucleotides and pyrimidine, purine, and cytokinin ribosides. A highly specific 5'(3')-ribonucleotide phosphohydrolase has been purified extensively from wheat seedling leaves. While catalyzing the hydrolysis of a wide variety of phosphomonoesters, the enzyme has K(m) values for adenosine 5'-monophosphate and adenosine 3'-monophosphate in the micromolar range and appears highly specific for 5'- and 3'-ribonucleoside monophosphates as substrates at pH 5.0. The cyclic nucleotides adenosine 3':5'-cyclic monophosphate, guanosine 3':5'-cyclic monophosphate, and 8-bromoadenosine 3':5'-cyclic monophosphate, as well as 8-bromoadenosine 5'-monophosphate, are powerful competitive inhibitors of the enzyme; the apparent K(i) values for these nucleotides are 3.4 muM, 1.6 muM, 26 muM, and 9.1 muM, respectively. The enzyme is inhibited noncompetitively by a variety of pyrimidine and purine (including cytokinin) ribosides and 2'-deoxyribosides. Since the cyclic nucleotide competitive inhibitors are also active growth promoters of higher plants, and, furthermore, since elevation of cyclic AMP levels appears to be a consequence of some phytohormone treatments that promote plant growth, it is suggested that negative control of this 5'(3')-ribonucleotide phosphohydrolase may be a significant component of growth regulation through the maximizing of the levels of nucleotide precursors for RNA and DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364532"}
{"pmid": "4364533", "title": "Rapid loss of translatable messenger RNA of phosphoenolpyruvate carboxykinase during glucose repression in liver.", "content": "Rapid loss of translatable messenger RNA of phosphoenolpyruvate carboxykinase during glucose repression in liver. The rate of synthesis of phosphoenolpyruvate carboxykinase (EC 4.1.1.32) in rat liver decreased with a half-life of 30 min after fasted rats were refed either a chow diet or glucose. A requirement for both glucose and insulin to bring about this rapid deinduction was shown, as well as the ability of dibutyryl adenosine 3':5'-cyclic monophosphate to block the decrease in enzyme synthesis. Estimates of the stability of messenger RNA of phosphoenolpyruvate carboxykinase were made by using the inhibitors actinomycin D and cordycepin to block further messenger RNA synthesis, and then measuring the decrease in specific enzyme synthesis. It is suggested that the use of actinomycin D yields an overestimation of the template stability. The results with cordycepin imply that the enzyme messenger RNA has a short half-life of approximately 1 hr. Thus, it is possible that deinduction may proceed by way of a decrease in messenger RNA production, leading to a rapid fall in the synthesis of phosphoenolpyruvate carboxykinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364533"}
{"pmid": "4364531", "title": "Viral DNA-RNA hybrids in cells infected with simian virus: the simian virus 40 transcriptional intermediates.", "content": "Viral DNA-RNA hybrids in cells infected with simian virus: the simian virus 40 transcriptional intermediates. Brief labeling of cells infected with simian virus 40 with tritiated uridine resulted in the incorporation of part of the label into material that was soluble in 1 M NaCl and sensitive to KOH, with a buoyant density close to that of DNA. The properties of this material suggest that it represents single-stranded nascent molecules of messenger RNA of simian virus 40 hydrogen-bonded over a small portion of their length to viral DNA templates. The name \"simian virus 40 transcriptional intermediate molecules\" is suggested for these naturally occurring DNA.RNA hybrid molecules. The DNA in the hybrid seems to be in the form of replicative intermediate molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364531"}
{"pmid": "4364537", "title": "The three-state model: a minimal allosteric description of homotropic and heterotropic effects in the binding of ligands to hemoglobin.", "content": "The three-state model: a minimal allosteric description of homotropic and heterotropic effects in the binding of ligands to hemoglobin. The effect of hydrogen ion, chloride, and 2,3-diphosphoglycerate upon the oxygen binding of hemoglobin may be satisfactorily described by an allosteric model employing three affinity states. The allosteric two-state model does not provide even an approximate description except under defined extreme conditions. In particular, the two-state model cannot provide a correct interpretation of recently reported electron spin resonance and nuclear magnetic resonance data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364537"}
{"pmid": "4364534", "title": "Cholinergic augmentation of lymphocyte-mediated cytotoxicity. A study of the cholinergic receptor of cytotoxic T lymphocytes.", "content": "Cholinergic augmentation of lymphocyte-mediated cytotoxicity. A study of the cholinergic receptor of cytotoxic T lymphocytes. Cholinergic agonists have previously been shown to augment the ability of sensitized lymphocytes to injure cells bearing the sensitizing alleantigens. The cholinergic receptor of the attacking lymphocyte population has been studied with pharmacological manipulation of an in vitro system that quantitates the injury mediated by sensitized attacking cells upon target cells. The data reveal that muscarinic ligands are several orders of magnitude more potent than nicotinic agents in altering cytotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364534"}
{"pmid": "4364535", "title": "Synthesis and properties of Clostridium acidi-urici (Leu2)-ferredoxin: a function of the peptide chain and evidence against the direct role of the aromatic residues in electron transfer.", "content": "Synthesis and properties of Clostridium acidi-urici (Leu2)-ferredoxin: a function of the peptide chain and evidence against the direct role of the aromatic residues in electron transfer. Tyrosyl or other aromatic residues generally occur in two conserved positions in the peptide chain of clostridial-type ferredoxins and have been implicated in the electron transfer function of these iron-sulfur proteins. We have prepared and determined some of the properties of a derivative of Clostridium acidi-urici ferredoxin, [Leu(2)]-ferredoxin, in which a leucyl residue has been substituted for the tyrosyl residue in position 2 from the amino terminus. [Leu(2)]-ferredoxin is fully active as an electron carrier in two biological assays, the phosphoroclastic enzyme system and the ferredoxin-dependent reduction of cytochrome c in the presence of ferredoxin-TPN reductase and TPNH. Quantitative electron paramagnetic resonance experiments indicate that [Leu(2)]-ferredoxin accepts nearly two electrons upon enzymatic reduction by pyruvate-ferredoxin oxidoreductase and an excess of pyruvate. If electron transfer to an iron-sulfur cluster is the rate-limiting step in the assays used, and if the rate of electron transfer through Tyr(30) is not much faster than through Tyr(2), these results indicate that the primary pathway of electron transfer in clostridial-type ferredoxins is not via Tyr or other aromatic amino-acid residues. The syntheses of other ferredoxin derivatives with amino-acid substitutions or deletions in positions 1 and 2 indicate that a large bulky residue, but not necessarily an aromatic residue, is needed in position 2 for the stability of this ferredoxin. The residue in position 2, therefore, appears to act as a hydrophobic shield for an iron-sulfur cluster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364535"}
{"pmid": "4364539", "title": "Renal aldosterone receptors: studies with (3H)aldosterone and the anti-mineralocorticoid (3H)spirolactone (SC-26304).", "content": "Renal aldosterone receptors: studies with (3H)aldosterone and the anti-mineralocorticoid (3H)spirolactone (SC-26304). In vivo, a spirolactone (SC-26304) inhibited the effects of aldosterone on urinary K(+):Na(+) ratios and the binding of [(3)H]aldosterone to renal cytoplasmic and nuclear receptors. Cytoplasmic binding of [(3)H]aldosterone and [(3)H]spirolactone (SC-26304) was similar in magnitude and involved the same set of sites. Under three sets of conditions-(i) in the intact rat, (ii) in kidney slices, and (iii) in reconstitution studies (mixing prelabeled cytoplasm with either purified renal nuclei or chromatin), [(3)H]spirolactone (SC-26304) did not yield specific nuclear complexes in contrast to the reproducible generation of these complexes with [(3)H]aldosterone. In glycerol density gradients, cytoplasmic [(3)H]aldosterone receptor complexes sedimented at 8.5 S and 4 S in low concentrations of salt and at 4.5 S in high concentrations of salt. Cytoplasmic [(3)H]spirolactone (SC-26304) receptor complexes sedimented at 3 S in low concentrations of salt and 4 S in high concentrations of salt. These results are discussed in terms of an allosteric model of the receptor system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364539"}
{"pmid": "4364536", "title": "Electron transfer reactions in biological systems: the reduction of ferricytochrome c by chromous ions.", "content": "Electron transfer reactions in biological systems: the reduction of ferricytochrome c by chromous ions. Chromous ion reacts with ferricytochrome c to yield a one-to-one Cr(III)-ferrocytochrome c complex. This material, when hydrolyzed by trypsin and subjected to chromatographic procedures, yielded two fragments containing chromium. The amino-acid compositions and chemical characteristics of each of these fragments indicated that the chromium had crosslinked two segments of polypeptide chain; these were residues 40-53-Cr(III)-residues 61-72 and residues 40-53-Cr(III)-residues 61-73. Examination of a model of the ferricytochrome c molecule indicated that only two residues of the crosslinked peptides were sufficiently close to allow crosslinking to take place. These residues were tyrosine 67 and asparagine 52. Enzymatic hydrolysis of one of those fragments by aminopeptidase M supported this identification. The position of the chromic ion implies what is the path of electron transfer from the chromous ion to the ferric ion in this chemical reduction of cytochrome c, and suggests a possible path of electron transfer in biological oxidation-reduction reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364536"}
{"pmid": "4364538", "title": "Epstein-Barr virus-associated membrane-reactive antibodies during long term survival Burkitt's lymphoma.", "content": "Epstein-Barr virus-associated membrane-reactive antibodies during long term survival Burkitt's lymphoma. Antibodies to Epstein-Barr virus associated cell membrane antigens persisted or slowly decreased during prolonged uncomplicated survival of patients with Burkitt's lymphoma in remission. Serum was sampled from four patients within 6 months before recurrence occurring after the first year and preceded by remission during more than 6 months. Rapid and significant decreases of the antibodies before clinical recognition of the recurrences were found in three patients. The fourth patient had slowly increasing titers before relapse. Immune stimulant treatment during remission, with BCG (Bacille Calmette Guérin vaccine) or BCG + Bordetella pertussis, temporarily increased the antibody levels. Possible mechanisms for the observed titer changes before recurrence are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364538"}
{"pmid": "4364541", "title": "Enhancement by carbachol of transmitter release from motor nerve terminals.", "content": "Enhancement by carbachol of transmitter release from motor nerve terminals. In the endplates of rat phrenic nerve-diaphragm, application of the acetylcholine-like compound, carbachol, causes a marked increase in transmitter release, as measured electrophysiologically using miniature endplate potential frequency. Washing out of carbachol reverses the increase in frequency. The ability of carbachol to increase transmitter release is greatly enhanced by perfusion of the preparation with Ringer solution containing elevated K(+). At concentrations of carbachol greater than 30 muM, the onset of the postjunctional blocking action of carbachol is too rapid and obscures the increase in miniature potential frequency. The rate of increase in transmitter release is dependent on the concentration of carbachol applied and can be antagonized by d-tubocurarine (10-60 nM) and other blocking compounds. These findings, in contrast to previous reports, indicate that cholinergic nerve endings, like adrenergic nerve endings, respond to applied acetylcholine-like drugs with measurable increases in transmitter output.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364541"}
{"pmid": "4364540", "title": "Cyclic 3':5'-adenosine monophosphate in Escherichia coli during transient and catabolite repression.", "content": "Cyclic 3':5'-adenosine monophosphate in Escherichia coli during transient and catabolite repression. Cyclic AMP concentrations were low for an adenylate cyclase-deficient mutant (cya(-)) and abnormally high for a catabolite receptor protein-deficient mutant (crp(-)). A fall in cellular cAMP concentration was always found when cells were subjected to transient repression. No consistent correlations were observed between catabolite repression and cellular cAMP levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364540"}
{"pmid": "4364543", "title": "A molecular model of high density lipoproteins.", "content": "A molecular model of high density lipoproteins. Based on the analysis of recombined lipidapoprotein complexes by C-13 and P-31 nuclear magnetic resonance spectroscopy and circular dichroism [Assmann, G., Sokoloski, E. A. & Brewer, H. B., Jr. (1974) Proc. Nat. Acad. Sci. USA 71, 549-553; Assmann, G., Highet, R. J., Sokoloski, E. A. & Brewer, H. B., Jr. (1974) Proc. Nat. Acad. Sci. USA 71, in press; Assmann, G. & Brewer, H. B., Jr. (1974) Proc. Nat. Acad. Sci. USA 71, 989-993] and the identification of conformational amphipathic regions in apoproteins, a new model for human high density lipoproteins is proposed. This model is analogous to membrane models proposed by Singer, in that protein \"icebergs\" are embedded in a \"sea\" of lipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364543"}
{"pmid": "4364542", "title": "Role of phosphate and other proton-donating anions in respiration-coupled transport of Ca2+ by mitochondria.", "content": "Role of phosphate and other proton-donating anions in respiration-coupled transport of Ca2+ by mitochondria. Measurements of extra oxygen consumption, (45)Ca(2+) uptake, and the osmotic expansion of the matrix compartment show that not all permeant anions are capable of supporting and accompanying the energy-dependent transport of Ca(2+) from the medium into the matrix in respiring rat-liver mitochondria. Phosphate, arsenate, acetate, butyrate, beta-hydroxybutyrate, lactate, and bicarbonate + CO(2) supported Ca(2+) uptake, whereas the permeant anions, nitrate, thiocyanate, chlorate, and perchlorate, did not. The active anions share a common denominator, the potential ability to donate a proton to the mitochondrial matrix; the inactive anions lack this capacity. Phosphate and the other active permeant anions move into the matrix in response to the alkaline-inside electrochemical gradient of protons generated across the mitochondrial membrane by electron transport, thus forming a negative-inside anion gradient. It is postulated that the latter gradient is the immediate \"pulling\" force for the influx of Ca(2+) on the electrogenic Ca(2+) carrier in respiring mitochondria under intracellular conditions. Since mitochondria in the cell are normally exposed to an excess of phosphate (and the bicarbonate-CO(2) system), particularly in state 4, inward transport of these proton-yielding anions probably precedes and is necessary for inward transport of Ca(2+) and other cations under biological conditions. These observations indicate that a negative-inside gradient of phosphate generated by electron transport is a common step and provides the immediate motive power not only for (a) the inward transport of dicarboxylates and tricarboxylates and (b) the energy-dependent exchange of external ADP(3-) for internal ATP(4-) during oxidative phosphorylation, as has already been established, but also for (c) the inward transport of Ca(2+), K(+), and other cations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364542"}
{"pmid": "4364552", "title": "Renal arteriovenous fistula secondary to metastatic tumor.", "content": "Renal arteriovenous fistula secondary to metastatic tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364552"}
{"pmid": "4364553", "title": "Wilms' tumor. Treatment in an adult.", "content": "Wilms' tumor. Treatment in an adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364553"}
{"pmid": "4364554", "title": "Effect of prolonged lithium ingestion on glucagon and parathyroid hormone responses in rats.", "content": "Effect of prolonged lithium ingestion on glucagon and parathyroid hormone responses in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364554"}
{"pmid": "4364556", "title": "Endocrine laboratory assays in obstetrics and gynecology.", "content": "Endocrine laboratory assays in obstetrics and gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364556"}
{"pmid": "4364558", "title": "Antifungal properties of polymyxin B and its potentiation of tetracycline as an antifungal agent.", "content": "Antifungal properties of polymyxin B and its potentiation of tetracycline as an antifungal agent. High concentrations of polymyxin B inhibited the growth of Candida albicans and Saccharomyces cerevisiae. When these yeasts were incubated with concentrations of polymyxin B too low to affect growth, and were then exposed to tetracycline, protein synthesis was inhibited and at least 99% of the organisms were killed. Neither inhibition of protein synthesis nor cell death occurred in cultures treated with high concentrations of tetracycline alone. We conclude that polymyxin B at high concentrations affects the cell membrane of yeasts, which results in inhibition of growth. At low concentrations, it increases the permeability of the yeast cell membrane to tetracycline, which then inhibits protein synthesis and leads to cell death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364558"}
{"pmid": "4364559", "title": "Location of the T4 gene 32 protein-binding site on polyoma virus DNA.", "content": "Location of the T4 gene 32 protein-binding site on polyoma virus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364559"}
{"pmid": "4364560", "title": "Interaction of N-methyl phenazinium radical cation with single-stranded polyriboadenylic acid.", "content": "Interaction of N-methyl phenazinium radical cation with single-stranded polyriboadenylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364560"}
{"pmid": "4364561", "title": "Localization of major group-specific polypeptides in the avian RNA tumor viruses.", "content": "Localization of major group-specific polypeptides in the avian RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364561"}
{"pmid": "4364562", "title": "Coupling of polyoma DNA and RNA synthesis.", "content": "Coupling of polyoma DNA and RNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364562"}
{"pmid": "4364563", "title": "Flavin binding by bacterial luciferase: affinity chromatography of bacterial luciferase.", "content": "Flavin binding by bacterial luciferase: affinity chromatography of bacterial luciferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364563"}
{"pmid": "4364564", "title": "Translation of mengovirus RNA in Ehrlich ascites cell extracts.", "content": "Translation of mengovirus RNA in Ehrlich ascites cell extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364564"}
{"pmid": "4364565", "title": "The effect of altered sterol composition on cytochrome oxidase and S-adenosylmethionine: delta 24 sterol methyltransferase enzymes of yeast mitochondria.", "content": "The effect of altered sterol composition on cytochrome oxidase and S-adenosylmethionine: delta 24 sterol methyltransferase enzymes of yeast mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364565"}
{"pmid": "4364566", "title": "A new eukaryotic RNA polymerase factor: a factor from chicken myeloblastosis cells which stimulates transcription of denatured DNA.", "content": "A new eukaryotic RNA polymerase factor: a factor from chicken myeloblastosis cells which stimulates transcription of denatured DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364566"}
{"pmid": "4364567", "title": "Isolation and terminal sequence determination of the major rat brain myelin proteolipid P7 apoprotein.", "content": "Isolation and terminal sequence determination of the major rat brain myelin proteolipid P7 apoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364567"}
{"pmid": "4364569", "title": "Effect of NH+4 and K+ on the activity of the ribosomal subunits in the EF-G- and EF-T-dependent GTR hydrolysis.", "content": "Effect of NH+4 and K+ on the activity of the ribosomal subunits in the EF-G- and EF-T-dependent GTR hydrolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364569"}
{"pmid": "4364568", "title": "Interaction of lysolecithin micelles and lecithin vesicles with apolipoprotein Gln I from serum high density lipoproteins.", "content": "Interaction of lysolecithin micelles and lecithin vesicles with apolipoprotein Gln I from serum high density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364568"}
{"pmid": "4364572", "title": "ALA synthetase induction. Inhibitory effect exerted by administration of dibutyryl adenosine-3',5'-cyclic monophosphate, theophylline and caffeine.", "content": "ALA synthetase induction. Inhibitory effect exerted by administration of dibutyryl adenosine-3',5'-cyclic monophosphate, theophylline and caffeine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364572"}
{"pmid": "4364573", "title": "Comparative study on induction of hepatic delta-aminolevulinate synthetase by different drugs.", "content": "Comparative study on induction of hepatic delta-aminolevulinate synthetase by different drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364573"}
{"pmid": "4364574", "title": "Are both fractions of Rhodopseudomonas spheroides Y ALA synthetase isoenzymes?", "content": "Are both fractions of Rhodopseudomonas spheroides Y ALA synthetase isoenzymes?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364574"}
{"pmid": "4364575", "title": "Protohaem synthesis by the yeast Saccharomyces cerevisiae during respiratory adaptation. Relationships with glycogen metabolism.", "content": "Protohaem synthesis by the yeast Saccharomyces cerevisiae during respiratory adaptation. Relationships with glycogen metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364575"}
{"pmid": "4364576", "title": "Vitamin D3 metabolites. I. Synthesis of 25-hydroxycholesterol.", "content": "Vitamin D3 metabolites. I. Synthesis of 25-hydroxycholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364576"}
{"pmid": "4364577", "title": "Vitamin D3 metabolites. II. Further syntheses of 25-hydroxycholesterol.", "content": "Vitamin D3 metabolites. II. Further syntheses of 25-hydroxycholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364577"}
{"pmid": "4364579", "title": "The cytoproct of Paramecium caudatum: structure and function, microtubules, and fate of food vacuole membranes.", "content": "The cytoproct of Paramecium caudatum: structure and function, microtubules, and fate of food vacuole membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364579"}
{"pmid": "4364578", "title": "Vitamin D3 metabolites. 3. Synthesis and X-ray analysis of 1 alpha,25-dihydroxycholesterol.", "content": "Vitamin D3 metabolites. 3. Synthesis and X-ray analysis of 1 alpha,25-dihydroxycholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364578"}
{"pmid": "4364581", "title": "Cell hybridization and cancer.", "content": "Cell hybridization and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364581"}
{"pmid": "4364582", "title": "Molecular pathology of the cancer cell.", "content": "Molecular pathology of the cancer cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364582"}
{"pmid": "4364580", "title": "Tumour-associated hormonal products.", "content": "Tumour-associated hormonal products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364580"}
{"pmid": "4364583", "title": "Effects of tumour viruses on cell growth.", "content": "Effects of tumour viruses on cell growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364583"}
{"pmid": "4364586", "title": "Characteristics of Sendai virus receptors in a model membrane.", "content": "Characteristics of Sendai virus receptors in a model membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364586"}
{"pmid": "4364584", "title": "Hormones and neoplasia.", "content": "Hormones and neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364584"}
{"pmid": "4364587", "title": "Replication of polyoma DNA in isolated nuclei. 3. The nucleotide sequence at the RNA-DNA junction of nascent strands.", "content": "Replication of polyoma DNA in isolated nuclei. 3. The nucleotide sequence at the RNA-DNA junction of nascent strands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364587"}
{"pmid": "4364588", "title": "Letter: Evidence for non-repetitive subunits in the genome of Rous sarcoma virus.", "content": "Letter: Evidence for non-repetitive subunits in the genome of Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364588"}
{"pmid": "4364589", "title": "Logical analysis of the mechanism of protein folding II. The nucleation process.", "content": "Logical analysis of the mechanism of protein folding II. The nucleation process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364589"}
{"pmid": "4364590", "title": "A re-examination of the renal blastema graft model for Wilms tumor production.", "content": "A re-examination of the renal blastema graft model for Wilms tumor production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364590"}
{"pmid": "4364594", "title": "Editorial: Vaccine against cytomegalovirus.", "content": "Editorial: Vaccine against cytomegalovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364594"}
{"pmid": "4364598", "title": "Spread of an avian adenovirus (CELO virus) to uninoculated fowls.", "content": "Spread of an avian adenovirus (CELO virus) to uninoculated fowls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364598"}
{"pmid": "4364599", "title": "The survival of foot-and-mouth disease virus in African buffalo with non-transference of infection to domestic cattle.", "content": "The survival of foot-and-mouth disease virus in African buffalo with non-transference of infection to domestic cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364599"}
{"pmid": "4364604", "title": "Errata: Demonstration of platelet fibrinogen secretion via the surface connecting system.", "content": "Errata: Demonstration of platelet fibrinogen secretion via the surface connecting system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364604"}
{"pmid": "4364603", "title": "Influence of human ceruloplasmin on the aggregation of human platelets by adenosine diphosphate.", "content": "Influence of human ceruloplasmin on the aggregation of human platelets by adenosine diphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364603"}
{"pmid": "4364605", "title": "Studies on the pathogenesis of iodide myxedema.", "content": "Studies on the pathogenesis of iodide myxedema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364605"}
{"pmid": "4364606", "title": "The mechanism of activation of hormone-sensitive lipase.", "content": "The mechanism of activation of hormone-sensitive lipase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364606"}
{"pmid": "4364607", "title": "Action of cholera toxin to stimulate adenyl cyclase.", "content": "Action of cholera toxin to stimulate adenyl cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364607"}
{"pmid": "4364608", "title": "Extracellular deoxyribonuclease production by anaerobic bacteria.", "content": "Extracellular deoxyribonuclease production by anaerobic bacteria. The production of extracellular deoxyribonuclease was examined with anaerobic organisms isolated from clinical specimens. Nuclease activity was extraordinarily common. All strains of Fusobacterium, including eight species, as well as Bacteroides fragilis and B. melaninogenicus, displayed enzyme activity. Whereas the gram-positive bacteria were generally less productive, all strains of Clostridium perfringens, Peptostreptococcus intermedius, and P. anaerobius specifically produced deoxyribonuclease. The test is taxonomically valuable, particularly in the characterization of gram-positive cocci, since a deoxyribonuclease-producing coccus indicates P. intermedius or P. anaerobius. Additionally, possession of the enzyme may prove to be a useful correlate of the potential pathogenicity of anaerobes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364608"}
{"pmid": "4364609", "title": "Method for isolation and selection of temperature-sensitive mutants of herpes simplex virus.", "content": "Method for isolation and selection of temperature-sensitive mutants of herpes simplex virus. A method for induction and selection of temperature-sensitive mutants of herpes simplex virus is presented. After the infected cells were treated with 5-bromodeoxyuridine, the virus was extracted by repeated freezing and thawing and cloned in microcultures which were then incubated at permissive temperature until viral plaques appeared. The microcultures were then replicated at nonpermissive temperature. Clones not forming plaques in these latter were further purified and examined for temperature-sensitive characteristics. Viral clones mutated in plaque-forming ability or in yield were obtained and preliminarily characterized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364609"}
{"pmid": "4364610", "title": "Effect of culture medium and carbon dioxide concentration on growth of anaerobic bacteria commonly encountered in clinical specimens.", "content": "Effect of culture medium and carbon dioxide concentration on growth of anaerobic bacteria commonly encountered in clinical specimens. Representative strains of anaerobic bacteria from human infections were used to evaluate broth media, gas mixtures, and inocula for use in developing a procedure for performing minimal inhibitory concentration antimicrobic susceptibility tests. Nine commercially available media, including two that were chemically defined, were tested. Tests were performed in atmospheres with carbon dioxide concentrations between 2.5 and 10% and also in the GasPak system (BBL) that had a disposable hydrogen-carbon dioxide generator. Growth curves on each organism grown in schaedler broth and a 5% carbon dioxide atmosphere were used to determine growth characteristics, equate time of the particular growth phases to turbidity readings, and determine the numbers of viable organisms present in the culture. Schaedler broth proved to be most advantageous in combination with an atmosphere of 5% carbon dioxide, 10% hydrogen, and 85% nitrogen. The growth curve studies yielded valuable data on the rapidity and quantity of growth under these conditions. We believe these data have provided information which can be used as the basis for developing a standardized procedure for antimicrobic susceptibility testing for anaerobic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364610"}
{"pmid": "4364611", "title": "Apparatus for conditioning unlimited quantities of finished waters for enteric virus detection.", "content": "Apparatus for conditioning unlimited quantities of finished waters for enteric virus detection. An apparatus has been developed, constructed, and tested for conditioning unlimited quantities of finished waters for enteric virus detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364611"}
{"pmid": "4364612", "title": "Metabolic adaptations in skeletal muscle of streptozotocin-diabetic rats following exercise training.", "content": "Metabolic adaptations in skeletal muscle of streptozotocin-diabetic rats following exercise training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364612"}
{"pmid": "4364613", "title": "Incorporation of 131-I-labeled androgen-receptor into nuclei of rat prostates.", "content": "Incorporation of 131-I-labeled androgen-receptor into nuclei of rat prostates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364613"}
{"pmid": "4364614", "title": "The influence of cyclic GMP on polypeptide synthesis in a cell-free system derived from wheat embryos.", "content": "The influence of cyclic GMP on polypeptide synthesis in a cell-free system derived from wheat embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364614"}
{"pmid": "4364616", "title": "The conformation of oxytocin in dimethylsulfoxide as revealed by carbon-13 spin-lattice relaxation times.", "content": "The conformation of oxytocin in dimethylsulfoxide as revealed by carbon-13 spin-lattice relaxation times.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364616"}
{"pmid": "4364615", "title": "An apolipoprotein preferentially enriched in cholesteryl ester-rich very low density lipoproteins.", "content": "An apolipoprotein preferentially enriched in cholesteryl ester-rich very low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364615"}
{"pmid": "4364617", "title": "Conversion of diglyceride to triglyceride by rat liver microsomes: a requirement for the 105,000 x g supernatant.", "content": "Conversion of diglyceride to triglyceride by rat liver microsomes: a requirement for the 105,000 x g supernatant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364617"}
{"pmid": "4364618", "title": "Cobalt cytochrome C: preparation of characterization.", "content": "Cobalt cytochrome C: preparation of characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364618"}
{"pmid": "4364619", "title": "Action of Solanum malacoxylon on calcium metabolism in the rat.", "content": "Action of Solanum malacoxylon on calcium metabolism in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364619"}
{"pmid": "4364621", "title": "Role of lecithin in D-beta-hydroxybutyrate dehydrogenase function.", "content": "Role of lecithin in D-beta-hydroxybutyrate dehydrogenase function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364621"}
{"pmid": "4364620", "title": "Selective chemical modification of arginine residues in mitochondrial malate dehydrogenase.", "content": "Selective chemical modification of arginine residues in mitochondrial malate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364620"}
{"pmid": "4364623", "title": "In vivo regulation of hepatic protein kinase by adenosine 3',5'-monophosphate mediated glucagon stimulation.", "content": "In vivo regulation of hepatic protein kinase by adenosine 3',5'-monophosphate mediated glucagon stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364623"}
{"pmid": "4364624", "title": "Synthesis of glucosylceramide by purified calf spleen beta-glucosidase.", "content": "Synthesis of glucosylceramide by purified calf spleen beta-glucosidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364624"}
{"pmid": "4364622", "title": "Soluble & membrane-bound superoxide dismutases in a blue-green algae (Spirulina)and spinach.", "content": "Soluble & membrane-bound superoxide dismutases in a blue-green algae (Spirulina)and spinach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364622"}
{"pmid": "4364625", "title": "Discharge patterns of cat raphe neurons during sleep and waking.", "content": "Discharge patterns of cat raphe neurons during sleep and waking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364625"}
{"pmid": "4364626", "title": "Developmental variations of choline acetyl-transferase, dopamine-beta-hydroxylase and monoamineoxidase in chicken embryo and chicken sympathetic ganglia.", "content": "Developmental variations of choline acetyl-transferase, dopamine-beta-hydroxylase and monoamineoxidase in chicken embryo and chicken sympathetic ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364626"}
{"pmid": "4364627", "title": "Connectivity changes of Ia afferents on axotomized motoneurons.", "content": "Connectivity changes of Ia afferents on axotomized motoneurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364627"}
{"pmid": "4364629", "title": "Two cAMP-activated protein kinases from bovine thyroid.", "content": "Two cAMP-activated protein kinases from bovine thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364629"}
{"pmid": "4364628", "title": "Streptomycin resistance and ribosomal proteins: amino acid substitutions in the str protein of one streptomycin-resistant mutant of Escherichia coli K12 after mutagenesis with ethyl methanesulfonate.", "content": "Streptomycin resistance and ribosomal proteins: amino acid substitutions in the str protein of one streptomycin-resistant mutant of Escherichia coli K12 after mutagenesis with ethyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364628"}
{"pmid": "4364630", "title": "The synthesis of diastereomeric epoxy-(beta-D-glucopyranosyl)ethanes and 1,2-epoxy-3-(beta-D-glucopyranosyl)propanes, as irreversible inhibitors of beta-D-glucosidase.", "content": "The synthesis of diastereomeric epoxy-(beta-D-glucopyranosyl)ethanes and 1,2-epoxy-3-(beta-D-glucopyranosyl)propanes, as irreversible inhibitors of beta-D-glucosidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364630"}
{"pmid": "4364631", "title": "Identification of iduronic acid as a constituent of the \"type-specific\" polysaccharide of Clostridium perfringens Hobbs 10.", "content": "Identification of iduronic acid as a constituent of the \"type-specific\" polysaccharide of Clostridium perfringens Hobbs 10.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364631"}
{"pmid": "4364632", "title": "The ultrastructure of the accessory sex organs of the male rat. VI. The effect of cyproterone acetate on the dorsal lobe and the coagulating gland.", "content": "The ultrastructure of the accessory sex organs of the male rat. VI. The effect of cyproterone acetate on the dorsal lobe and the coagulating gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364632"}
{"pmid": "4364633", "title": "The development and fine structure of the ultimobranchial glands in larval Rana temporaria L.", "content": "The development and fine structure of the ultimobranchial glands in larval Rana temporaria L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364633"}
{"pmid": "4364634", "title": "Developmental genetics of teleosts: a biochemical analysis of lake chubsucker ontogeny.", "content": "Developmental genetics of teleosts: a biochemical analysis of lake chubsucker ontogeny.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364634"}
{"pmid": "4364635", "title": "The content of pyridine dinucleotides in the mouse embryo before implantation.", "content": "The content of pyridine dinucleotides in the mouse embryo before implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364635"}
{"pmid": "4364636", "title": "Effect of phenobarbital administration on the subcellular distribution of vitamin D3-3H in rat liver.", "content": "Effect of phenobarbital administration on the subcellular distribution of vitamin D3-3H in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364636"}
{"pmid": "4364637", "title": "Effects of calcitonin in the concentration of cyclic adenosine 3',5'-monophosphate in rat kidney in vivo and in vitro.", "content": "Effects of calcitonin in the concentration of cyclic adenosine 3',5'-monophosphate in rat kidney in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364637"}
{"pmid": "4364639", "title": "Embryonic chick intestine in organ culture: interaction of adenylate cyclase system and vitamin D3-mediated calcium absorptive mechanism.", "content": "Embryonic chick intestine in organ culture: interaction of adenylate cyclase system and vitamin D3-mediated calcium absorptive mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364639"}
{"pmid": "4364638", "title": "Purified somatotrophs from rat adenohypophysis: response to secretagogues.", "content": "Purified somatotrophs from rat adenohypophysis: response to secretagogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364638"}
{"pmid": "4364640", "title": "Thyrotropin-releasing hormone stimulation and somatostatin inhibition of growth hormone secretion from perfused rat adenohypophyses.", "content": "Thyrotropin-releasing hormone stimulation and somatostatin inhibition of growth hormone secretion from perfused rat adenohypophyses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364640"}
{"pmid": "4364641", "title": "Observations on the effects of chromate on the thyroid.", "content": "Observations on the effects of chromate on the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364641"}
{"pmid": "4364642", "title": "Secretion of ACTH by isolated anterior pituitary cells: kinetics of stimulation of corticotropin-releasing factor and of inhibition by corticosterone.", "content": "Secretion of ACTH by isolated anterior pituitary cells: kinetics of stimulation of corticotropin-releasing factor and of inhibition by corticosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364642"}
{"pmid": "4364643", "title": "Mineralocorticoid receptors in salt-susceptible and salt-resistant rats.", "content": "Mineralocorticoid receptors in salt-susceptible and salt-resistant rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364643"}
{"pmid": "4364645", "title": "Lead-induced inclusion bodies: composition and probable role in lead metabolism.", "content": "Lead-induced inclusion bodies: composition and probable role in lead metabolism. Lead-induced inclusion bodies in renal tubular cells of rats have been studied in vitro after isolation by differential centrifugation. The inclusion bodies are insoluble in physiological media but may be dissolved in denaturants like 6M urea and sodium deoxycholate. They contain about 40-50 mug of lead/mg protein, but only about 10% of this is tightly bound. They also contain calcium, iron, zinc, copper, and cadmium. The protein is rich in glutamic and aspartic acids, glycine and cystine. When dissolved in 6M urea, the protein migrates as a single band on acrylamide gel electrophoresis and has a molecular weight of 27,500. It is suggested that the inclusion bodies function as an intracellular depot of nondiffusible lead. Further studies have been directed toward finding a free, unaggregated lead-containing protein fraction. Nuclear proteins from kidneys of lead-toxic rats were separated into NaCl-, Tris-, and NaOH-soluble fractions and an insoluble acidic fraction. A quantitatively small lead-containing protein was found in the 0.14M NaCl fraction. Amino acid composition, electrophoretic mobility, molecular weight, and ability to bind lead are similar to those of insoluble inclusion body protein. The possible role of this soluble lead-binding protein in the formation of nuclear inclusion bodies is at present time not certain. These studies do suggest, however, that protein-bound lead in renal tubular cells may be partitioned between insoluble and nondiffusible morphologically discrete inclusion bodies and a soluble, extractable fraction which is presumably diffusable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364645"}
{"pmid": "4364644", "title": "Lead aggravates viral disease and represses the antiviral activity of interferon inducers.", "content": "Lead aggravates viral disease and represses the antiviral activity of interferon inducers. Lead acetate was administered continuously in the drinking water to CD-1 male mice beginning at 4 weeks of age. An LD(10-20) of the lytic viruses or 300 plaque-forming units of RLV was inoculated intrapertioneally at 6 weeks of age. Lead increased the response of the mice to all classes of viruses against which it was tested: an RNA picornavirus-encephalomyocarditis (EMCV), a DNA herpesvirus-pseudoribies, an RNA leukemia-virus-Rauscher leukemia (RLV), an RNA arbovirus B-St. Louis encephalitis, and an RNA arbovirus A-western encephalitis. Most studies were performed between lead and EMCV. Increases in EMCV mortality in lead treated mice over controls ranged from 2x at a lead level of 0.004M to 7x (100% mortality) at a 0.1M lead level. Splenomegaly with spleens 800 to 1100 mg in weight containing high titers of RLV occurred in lead (0.03M)-treated mice 3 and 6 weeks after RLV inoculation; spleens or RLV controls were normal in weight (200 mg) and were free of virus. Lead did not reduce the protective effect of mouse interferon (IF) against the lethal action of EMCV, but it did repress the EMCV antiviral effect of poly I/poly C (PIC) and of Newcastle disease virus (NDV) against EMCV mortality. These data indicate several new facts concerning adverse effects lead may have on an animal: (1) lead aggravates viral disease, most likely in part, through reduced IF synthesis; (2) lead represses the anti-EMCV protective effects of both PIC and of NDV, which, in other reports, were shown to induce IF in radioresistant macrophages (PIC) or in radiosensitive lymphocytes (NDV); (3) lead may then be said to repress IF induction in two kinds of cells; (4) however, lead does not inhibit IF action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364644"}
{"pmid": "4364647", "title": "Demonstration of a reaggregation inhibitor in sea urchin embryos.", "content": "Demonstration of a reaggregation inhibitor in sea urchin embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364647"}
{"pmid": "4364648", "title": "Retraction fibers and leucocyte chemotaxis.", "content": "Retraction fibers and leucocyte chemotaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364648"}
{"pmid": "4364646", "title": "Red cell lead, whole blood lead, and red cell enzymes.", "content": "Red cell lead, whole blood lead, and red cell enzymes. Simultaneous assay of blood lead (Pb-B) and red cell lead (Pb-Rbc) in 123 samples from 104 urban and suburban students, ages 10-18, shows the ratio of concentration (Pb-Rbc)/(Pb-B) to increase as the hematocrit decreases. On direct assay in 40 samples, plasma lead (Pb-P) was fixed in a narrow range. In 28 students with Pb-Rbc >40 mug/100 ml, the mean red cell 2,3-diphosphoglycerate (2,3-DPG) was 6.05+/-0.28 (+/-S.E.), significantly higher (P<.025) than the 5.25+/-0.18 of 51 students with Pb-Rbc<40 mug/100 ml, although hemoglobin values were comparable (13.83+/-0.31 versus 13.55+/-0.20). Analysis of the individual population groups showed this correlation of Pb-Rbc with 2,3-DPG to be primarily related to the intercorrelation of each parameter with hemoglobin.Rbc membrane Na/K ATPase, as per cent of total membrane ATPase, had a median value of 60% in 48 subjects. Na/K ATPase below 60% was found in 10 (77%) of the 13 students with Pb-Rbc>/=40 mug/100 ml, but in only 14 of the 35 with Pb-Rbc<40 mug/100 ml (chi(2)=5.1, df=1, P<0.05). Correlation of significant enzyme changes with Pb-Rbc, but not with Pb-B in the normal urban range of Pb-B<35 mug/100 ml suggests Pb-Rbc, increased in anemia, to be a critical factor in the hematotoxicity of lead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364646"}
{"pmid": "4364649", "title": "Effect of proteolytic inhibitors on growth and surface architecture of normal and transformed cells.", "content": "Effect of proteolytic inhibitors on growth and surface architecture of normal and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364649"}
{"pmid": "4364650", "title": "Uncoupler-stimulated adenosine triphosphatase activity. Deficiency in intact mitochondria from Morris hepatomas and ascites tumor cells.", "content": "Uncoupler-stimulated adenosine triphosphatase activity. Deficiency in intact mitochondria from Morris hepatomas and ascites tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364650"}
{"pmid": "4364651", "title": "Sugar transport in chick embryo fibroblasts. II. Alterations in transport following transformation by a temperature-sensitive mutant of the Rous sarcoma virus.", "content": "Sugar transport in chick embryo fibroblasts. II. Alterations in transport following transformation by a temperature-sensitive mutant of the Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364651"}
{"pmid": "4364652", "title": "The isolation and partial characterization of two novel sphingolipids from Neurospora crassa: di(inositolphosphoryl)ceramide and ((gal)3glu)ceramide.", "content": "The isolation and partial characterization of two novel sphingolipids from Neurospora crassa: di(inositolphosphoryl)ceramide and ((gal)3glu)ceramide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364652"}
{"pmid": "4364653", "title": "Inositol phosphorylceramide, a novel substance and the chief member of a major group of yeast sphingolipids containing a single inositol phosphate.", "content": "Inositol phosphorylceramide, a novel substance and the chief member of a major group of yeast sphingolipids containing a single inositol phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364653"}
{"pmid": "4364654", "title": "Nucleoside diphosphokinase of Salmonella typhimurium.", "content": "Nucleoside diphosphokinase of Salmonella typhimurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364654"}
{"pmid": "4364656", "title": "Thermodynamic parameters for the hydrolysis of inorganic pyrophosphate at pH 7.4 as a function of (Mg2+), (K+), and ionic strength determined from equilibrium studies of the reaction.", "content": "Thermodynamic parameters for the hydrolysis of inorganic pyrophosphate at pH 7.4 as a function of (Mg2+), (K+), and ionic strength determined from equilibrium studies of the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364656"}
{"pmid": "4364655", "title": "Inhibition of macromolecular synthesis in Escherichia coli by protease inhibitors. Specific reversal by glutathione of the effects of chloromethyl ketones.", "content": "Inhibition of macromolecular synthesis in Escherichia coli by protease inhibitors. Specific reversal by glutathione of the effects of chloromethyl ketones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364655"}
{"pmid": "4364657", "title": "Regulation of protein synthesis during density-dependent growth inhibition of BHK21-13 cells.", "content": "Regulation of protein synthesis during density-dependent growth inhibition of BHK21-13 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364657"}
{"pmid": "4364658", "title": "Isolation and relationship of human hexosaminidases.", "content": "Isolation and relationship of human hexosaminidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364658"}
{"pmid": "4364659", "title": "The equilibria and reaction rates of nicotinamide-adenine dinucleotide and its related compounds with cyanide ion in the presence of polyelectrolytes.", "content": "The equilibria and reaction rates of nicotinamide-adenine dinucleotide and its related compounds with cyanide ion in the presence of polyelectrolytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364659"}
{"pmid": "4364660", "title": "Differential effects of adenylyl imidodiphosphate on adenosine triphosphate synthesis and the partial reactions of oxidative phosphorylation.", "content": "Differential effects of adenylyl imidodiphosphate on adenosine triphosphate synthesis and the partial reactions of oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364660"}
{"pmid": "4364661", "title": "Studies with cyclic adenosine monophosphate receptor and stimulation of in vitro transcription of the Gal operon.", "content": "Studies with cyclic adenosine monophosphate receptor and stimulation of in vitro transcription of the Gal operon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364661"}
{"pmid": "4364662", "title": "Stimulation and desensitization of macrophage adenylate cyclase by prostaglandins and catecholamines.", "content": "Stimulation and desensitization of macrophage adenylate cyclase by prostaglandins and catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364662"}
{"pmid": "4364663", "title": "The enhancement of macrophage adenylate cyclase by products of activated lymphocytes.", "content": "The enhancement of macrophage adenylate cyclase by products of activated lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364663"}
{"pmid": "4364664", "title": "Casein kinase from the Golgi apparatus of lactating mammary gland.", "content": "Casein kinase from the Golgi apparatus of lactating mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364664"}
{"pmid": "4364665", "title": "Formation of a novel nucleotide by fat cell preparations containing adenylate cyclase.", "content": "Formation of a novel nucleotide by fat cell preparations containing adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364665"}
{"pmid": "4364667", "title": "The determination of low density lipoproteins by micro-nephelometry: a practical assessment.", "content": "The determination of low density lipoproteins by micro-nephelometry: a practical assessment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364667"}
{"pmid": "4364666", "title": "A histochemical characterization of malignant tumour mucins as a possible aid in the identification of metastatic deposits.", "content": "A histochemical characterization of malignant tumour mucins as a possible aid in the identification of metastatic deposits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364666"}
{"pmid": "4364670", "title": "Cystosarcoma phylloides in a twelve-year-old girl.", "content": "Cystosarcoma phylloides in a twelve-year-old girl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364670"}
{"pmid": "4364672", "title": "Studies on growth homone secretion. VI. Effects of dibutyryl cyclic AMP, prostaglandin E1, and indomethacin on growth and hormone secretion by rat pituitary tumor cells in culture.", "content": "Studies on growth homone secretion. VI. Effects of dibutyryl cyclic AMP, prostaglandin E1, and indomethacin on growth and hormone secretion by rat pituitary tumor cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364672"}
{"pmid": "4364673", "title": "Cyclic AMP regulation of prostaglandin biosynthesis in fat cells.", "content": "Cyclic AMP regulation of prostaglandin biosynthesis in fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364673"}
{"pmid": "4364678", "title": "The effect of L-tryptophane upon the elaboration and extinction of a conditioned avoidance response and upon the behaviour of rats.", "content": "The effect of L-tryptophane upon the elaboration and extinction of a conditioned avoidance response and upon the behaviour of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364678"}
{"pmid": "4364679", "title": "Cyclic AMP-dependent protein kinase activity in a cell membrane-enriched subcellular fraction of pig myocardium.", "content": "Cyclic AMP-dependent protein kinase activity in a cell membrane-enriched subcellular fraction of pig myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364679"}
{"pmid": "4364680", "title": "Binding of calcium to a cell membrane-enriched preparation from pig myocardium: increase in calcium affinity upon membrane protein phosphorylation enhanced by a membrane-bound cyclic AMP-dependent protein kinase.", "content": "Binding of calcium to a cell membrane-enriched preparation from pig myocardium: increase in calcium affinity upon membrane protein phosphorylation enhanced by a membrane-bound cyclic AMP-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364680"}
{"pmid": "4364681", "title": "Subcellular localisation and properties of contractile protein ATPases of blood platelets.", "content": "Subcellular localisation and properties of contractile protein ATPases of blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364681"}
{"pmid": "4364682", "title": "Cyclic AMP and platelet aggregation.", "content": "Cyclic AMP and platelet aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364682"}
{"pmid": "4364684", "title": "The release reaction.", "content": "The release reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364684"}
{"pmid": "4364683", "title": "Platelet aggregation in the rat--relation to human thrombopathias.", "content": "Platelet aggregation in the rat--relation to human thrombopathias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364683"}
{"pmid": "4364685", "title": "Enzymes of purine metabolism in platelets: phosphoribosylpyrophosphate synthetase and purine phosphoribosyltransferases.", "content": "Enzymes of purine metabolism in platelets: phosphoribosylpyrophosphate synthetase and purine phosphoribosyltransferases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364685"}
{"pmid": "4364686", "title": "Hypoxanthine-guanine phosphoribosyltransferase deficiency: altered kinetic properties of a specific mutant form of the enzyme.", "content": "Hypoxanthine-guanine phosphoribosyltransferase deficiency: altered kinetic properties of a specific mutant form of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364686"}
{"pmid": "4364687", "title": "Mutant phosphoribosylpyrophosphate synthetase in two gouty siblings with excessive purine production.", "content": "Mutant phosphoribosylpyrophosphate synthetase in two gouty siblings with excessive purine production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364687"}
{"pmid": "4364689", "title": "An unusual case of glycogen storage disease.", "content": "An unusual case of glycogen storage disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364689"}
{"pmid": "4364690", "title": "Human glltamine phosphoribosylpyrophosphate (PP-ribose-P) amidotransferase: kinetic, regulation and configurational changes.", "content": "Human glltamine phosphoribosylpyrophosphate (PP-ribose-P) amidotransferase: kinetic, regulation and configurational changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364690"}
{"pmid": "4364688", "title": "Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.", "content": "Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364688"}
{"pmid": "4364692", "title": "Human phosphoribosylpyrophosphate (PP-ribose-P) synthetase: properties and regulation.", "content": "Human phosphoribosylpyrophosphate (PP-ribose-P) synthetase: properties and regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364692"}
{"pmid": "4364693", "title": "Regulatory aspects of the synthesis of 5-phosphoribosyl-1-pyrophosphate in human red blood cells.", "content": "Regulatory aspects of the synthesis of 5-phosphoribosyl-1-pyrophosphate in human red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364693"}
{"pmid": "4364691", "title": "Xanthine oxidase and aldehyde oxidase in purine and purine analogue metabolism.", "content": "Xanthine oxidase and aldehyde oxidase in purine and purine analogue metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364691"}
{"pmid": "4364695", "title": "Familial association of metabolic myopathy, lactic acidosis and sideroblastic anemia.", "content": "Familial association of metabolic myopathy, lactic acidosis and sideroblastic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364695"}
{"pmid": "4364694", "title": "Hormonal control of skeletal and mineral homeostasis.", "content": "Hormonal control of skeletal and mineral homeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364694"}
{"pmid": "4364697", "title": "Catalytic properties of three lactate dehydrogenases from potato tubers (Solanum tuberosum).", "content": "Catalytic properties of three lactate dehydrogenases from potato tubers (Solanum tuberosum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364697"}
{"pmid": "4364696", "title": "Fat metabolism in higher plants. Recent studies on plant alpha-oxidation systems.", "content": "Fat metabolism in higher plants. Recent studies on plant alpha-oxidation systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364696"}
{"pmid": "4364699", "title": "Effects of visual pigments on the organization of phospholipid multibilayer model membranes--a spin probe study.", "content": "Effects of visual pigments on the organization of phospholipid multibilayer model membranes--a spin probe study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364699"}
{"pmid": "4364698", "title": "Regulatory sulfhydryl groups, conformational change, and allosteric inhibition in rabbit muscle fructose diphosphatase.", "content": "Regulatory sulfhydryl groups, conformational change, and allosteric inhibition in rabbit muscle fructose diphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364698"}
{"pmid": "4364703", "title": "The effect of sulisoxazole (Gantrisin) and albumin on bilirubin conjugation in cultures of a clonal cell line with liver-like functions.", "content": "The effect of sulisoxazole (Gantrisin) and albumin on bilirubin conjugation in cultures of a clonal cell line with liver-like functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364703"}
{"pmid": "4364705", "title": "Changes in apolipoproteins and properties of rabbit very low density lipoproteins on induction of cholesteremia.", "content": "Changes in apolipoproteins and properties of rabbit very low density lipoproteins on induction of cholesteremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364705"}
{"pmid": "4364702", "title": "The mode of action of metronidazole in Trichomonas vaginalis and other micro-organisms.", "content": "The mode of action of metronidazole in Trichomonas vaginalis and other micro-organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364702"}
{"pmid": "4364704", "title": "Antibodies to the unfolded form of a helix-rich region in staphylococcal nuclease.", "content": "Antibodies to the unfolded form of a helix-rich region in staphylococcal nuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364704"}
{"pmid": "4364706", "title": "Two pictures of a lipid bilayer. A comparison between deuterium label and spin-label experiments.", "content": "Two pictures of a lipid bilayer. A comparison between deuterium label and spin-label experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364706"}
{"pmid": "4364708", "title": "Tritium-hydrogen exchange of the cyclic peptide polymyxin B-1.", "content": "Tritium-hydrogen exchange of the cyclic peptide polymyxin B-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364708"}
{"pmid": "4364709", "title": "Magnetic resonance studies of the geometry of bound nicotinamide adenine dinucleotide and isobutyramide on spin-labeled alcohol dehydrogenase.", "content": "Magnetic resonance studies of the geometry of bound nicotinamide adenine dinucleotide and isobutyramide on spin-labeled alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364709"}
{"pmid": "4364710", "title": "Specificity of chemical modification of ribonucleic acid transport by liver carcinogens in the rat.", "content": "Specificity of chemical modification of ribonucleic acid transport by liver carcinogens in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364710"}
{"pmid": "4364707", "title": "Enzymatic synthesis of deoxyribonucleic acids with repeating sequences. A new repeating trinucleotide deoxyribonucleic acid, d(T-C-C)n-d(G-G-A)n.", "content": "Enzymatic synthesis of deoxyribonucleic acids with repeating sequences. A new repeating trinucleotide deoxyribonucleic acid, d(T-C-C)n-d(G-G-A)n.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364707"}
{"pmid": "4364711", "title": "Binding of lanthanides and of divalent metal ions to porcine trypsin.", "content": "Binding of lanthanides and of divalent metal ions to porcine trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364711"}
{"pmid": "4364714", "title": "Protective effect of interferon on mice experimentally infected with Japanese encephalitis virus.", "content": "Protective effect of interferon on mice experimentally infected with Japanese encephalitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364714"}
{"pmid": "4364716", "title": "Improving psychiatric drug therapy. A matter of dosage and choice.", "content": "Improving psychiatric drug therapy. A matter of dosage and choice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364716"}
{"pmid": "4364717", "title": "Inhibition of hepatoma-immune lymph-node cell cytotoxicity by tumour-bearer serum, and solubilized hepatoma antigen.", "content": "Inhibition of hepatoma-immune lymph-node cell cytotoxicity by tumour-bearer serum, and solubilized hepatoma antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364717"}
{"pmid": "4364718", "title": "Inheritance of susceptibility to Friend mouse leukemia virus. X. Separate genetic control of two viruses in Friend virus preparation.", "content": "Inheritance of susceptibility to Friend mouse leukemia virus. X. Separate genetic control of two viruses in Friend virus preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364718"}
{"pmid": "4364719", "title": "Specific neutralizing antibodies in Epstein-Barr virus associated diseases.", "content": "Specific neutralizing antibodies in Epstein-Barr virus associated diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364719"}
{"pmid": "4364720", "title": "Influence of age and 3-methylcholanthrene on azo-dye carcinogenesis and metabolism of p-dimethylaminoazobenzene in rat liver.", "content": "Influence of age and 3-methylcholanthrene on azo-dye carcinogenesis and metabolism of p-dimethylaminoazobenzene in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364720"}
{"pmid": "4364722", "title": "The effects of long-term feeding of DDT to BALB-c mice.", "content": "The effects of long-term feeding of DDT to BALB-c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364722"}
{"pmid": "4364721", "title": "Increase in viral antigen in individual polyoma-virus-infected mouse kidney cells as studied by quantiative immunofluorescence.", "content": "Increase in viral antigen in individual polyoma-virus-infected mouse kidney cells as studied by quantiative immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364721"}
{"pmid": "4364723", "title": "A rapid destructive effect of the Schmidt-Ruppin strain of Rous sarcoma virus on transformed rat cell lines.", "content": "A rapid destructive effect of the Schmidt-Ruppin strain of Rous sarcoma virus on transformed rat cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364723"}
{"pmid": "4364726", "title": "Extraction and analysis of carotenoids in fresh plant materials.", "content": "Extraction and analysis of carotenoids in fresh plant materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364726"}
{"pmid": "4364724", "title": "Genetic control of MuLV-gs expression in crosses between high and low leukemia incidence strains.", "content": "Genetic control of MuLV-gs expression in crosses between high and low leukemia incidence strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364724"}
{"pmid": "4364725", "title": "Cherubism.", "content": "Cherubism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364725"}
{"pmid": "4364729", "title": "Failure to detect, in human sera, antibodies cross-reactive with group-specific antigens of murine leukemia virus.", "content": "Failure to detect, in human sera, antibodies cross-reactive with group-specific antigens of murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364729"}
{"pmid": "4364727", "title": "Rapid screening method for analysis of chlorinated pesticide and polychlorinated biphenyl residues in fish.", "content": "Rapid screening method for analysis of chlorinated pesticide and polychlorinated biphenyl residues in fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364727"}
{"pmid": "4364728", "title": "Rapid screening method for examining corn and corn-derived products for possible aflatoxin contamination.", "content": "Rapid screening method for examining corn and corn-derived products for possible aflatoxin contamination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364728"}
{"pmid": "4364731", "title": "A rapid dialysis cell in the zirconyl gel assay for carcinoembryonic antigen in human serum.", "content": "A rapid dialysis cell in the zirconyl gel assay for carcinoembryonic antigen in human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364731"}
{"pmid": "4364730", "title": "Chemodectomas in dogs: epidemiologic comparisons with man.", "content": "Chemodectomas in dogs: epidemiologic comparisons with man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364730"}
{"pmid": "4364733", "title": "Responses of isolator-derived and conventional chickens to Marek's disease herpesvirus and avian leukosis virus.", "content": "Responses of isolator-derived and conventional chickens to Marek's disease herpesvirus and avian leukosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364733"}
{"pmid": "4364732", "title": "Prevalence of endogenous type-C virus in normal hamster tissues and hamster tumors induced by chemical carcinogens, simian virus 40, and polyoma virus.", "content": "Prevalence of endogenous type-C virus in normal hamster tissues and hamster tumors induced by chemical carcinogens, simian virus 40, and polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364732"}
{"pmid": "4364734", "title": "Effect of aminoacetonitrile on the metabolism of diethylnitrosamine during liver carcinogenesis.", "content": "Effect of aminoacetonitrile on the metabolism of diethylnitrosamine during liver carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364734"}
{"pmid": "4364735", "title": "Transmission of the mammary tumor virus by the GR mouse strain. II. Genetic studies.", "content": "Transmission of the mammary tumor virus by the GR mouse strain. II. Genetic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364735"}
{"pmid": "4364737", "title": "Potential carcinogens. I. Carcinogenicity of some plant extracts and their tannin-containing fractions in rats.", "content": "Potential carcinogens. I. Carcinogenicity of some plant extracts and their tannin-containing fractions in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364737"}
{"pmid": "4364736", "title": "Immunotherapy of cancer: regression of established intradermal tumors after intralesional injection of mycobacterial cell walls attached to oil droplets.", "content": "Immunotherapy of cancer: regression of established intradermal tumors after intralesional injection of mycobacterial cell walls attached to oil droplets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364736"}
{"pmid": "4364738", "title": "BALB-cfR3: a new high mammary-tumor and high leukemia mouse strain.", "content": "BALB-cfR3: a new high mammary-tumor and high leukemia mouse strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364738"}
{"pmid": "4364739", "title": "Protection against guinea pig hepatomas by pretreatment with subcelluar fractions of Mycobacterium bovis (BCG).", "content": "Protection against guinea pig hepatomas by pretreatment with subcelluar fractions of Mycobacterium bovis (BCG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364739"}
{"pmid": "4364740", "title": "Hepatocarcinogenic material in urine specimens from humans consuming aflatoxin.", "content": "Hepatocarcinogenic material in urine specimens from humans consuming aflatoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364740"}
{"pmid": "4364741", "title": "A one cell-cycle delay for tumor cytostasis in vitro: effects of dibutyryl cyclic AMP or embryonic extracts on synchronized cultures of a murine tumor.", "content": "A one cell-cycle delay for tumor cytostasis in vitro: effects of dibutyryl cyclic AMP or embryonic extracts on synchronized cultures of a murine tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364741"}
{"pmid": "4364744", "title": "Effect of soluble and membrane proteins upon diethyl ether extraction of aqueous phospholipid dispersions.", "content": "Effect of soluble and membrane proteins upon diethyl ether extraction of aqueous phospholipid dispersions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364744"}
{"pmid": "4364745", "title": "Bis-(monoacylglyceryl)phosphate and acyl phosphatidylglycerol isolated from human livers of lipidosis induced by 4,4'-diethylaminoethoxyhexesterol.", "content": "Bis-(monoacylglyceryl)phosphate and acyl phosphatidylglycerol isolated from human livers of lipidosis induced by 4,4'-diethylaminoethoxyhexesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364745"}
{"pmid": "4364746", "title": "Phospholipids of two strains of dermatophyte, Arthroderma uncinatum.", "content": "Phospholipids of two strains of dermatophyte, Arthroderma uncinatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364746"}
{"pmid": "4364748", "title": "Biological characters of Staphylococcus aureus isolated from diseased chickens.", "content": "Biological characters of Staphylococcus aureus isolated from diseased chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364748"}
{"pmid": "4364749", "title": "Axonal filamentous spheroids associated with cardiomyopathy with \"targetoid fibers\". I. Clinical, histologic, and electron microscopic studies.", "content": "Axonal filamentous spheroids associated with cardiomyopathy with \"targetoid fibers\". I. Clinical, histologic, and electron microscopic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364749"}
{"pmid": "4364751", "title": "Malignant tumors of the trachea. A new outlook.", "content": "Malignant tumors of the trachea. A new outlook.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364751"}
{"pmid": "4364752", "title": "Diabetes and Addison's disease.", "content": "Diabetes and Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364752"}
{"pmid": "4364754", "title": "Flunitrazepam (Ro 5-4200) and sleep cycle in insomniac patients.", "content": "Flunitrazepam (Ro 5-4200) and sleep cycle in insomniac patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364754"}
{"pmid": "4364755", "title": "Cytochemical observations on the midpiece of the spermatozoa of the gastropod Biomphalaria glabrata.", "content": "Cytochemical observations on the midpiece of the spermatozoa of the gastropod Biomphalaria glabrata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364755"}
{"pmid": "4364758", "title": "A case of Raynaud's syndrome of peculiar origin.", "content": "A case of Raynaud's syndrome of peculiar origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364758"}
{"pmid": "4364759", "title": "Is the inhibition of glutamic-pyruvic transaminase by phenylalanine one of the causes of hypoglucosemia in phenylketonurics?", "content": "Is the inhibition of glutamic-pyruvic transaminase by phenylalanine one of the causes of hypoglucosemia in phenylketonurics?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364759"}
{"pmid": "4364760", "title": "Latest developments in the treatment of amebiasis.", "content": "Latest developments in the treatment of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364760"}
{"pmid": "4364761", "title": "Adrenocortical responses of the Apollo 17 crew members.", "content": "Adrenocortical responses of the Apollo 17 crew members.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364761"}
{"pmid": "4364762", "title": "In vitro antiviral activity and preliminary clinical trials of a new adamantane compound.", "content": "In vitro antiviral activity and preliminary clinical trials of a new adamantane compound. A compound, 1'-methyl spiro (adamantane-2,3'-pyrrolidine) maleate, chemically related to the antiviral drug amantadine, was tested for activity in vitro against a number of human respiratory viruses. By a variety of techniques, it was shown to be active against a wide range of human and animal influenza A viruses. The effect was, however, variable and ranged from high activity against two 1957 Asian strains to no observable activity against a 1971 strain. Like amantadine, the drug did not inhibit the growth of influenza B viruses. It was also inactive against a number of paramyxoviruses. Unlike amantadine, the drug did inhibit rhinoviruses, but to a lesser extent than myxoviruses. The coronavirus 229E was also sensitive to the action of the drug in vitro. Although an earlier trial in volunteers showed that, when given orally from 2 days before until 5 days after virus challenge, the drug was protective against infection with influenza A/Hong Kong/68 virus, a similar trial in volunteers challenged with rhinoviruses 2 and 9 revealed no useful activity against rhinoviruses in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364762"}
{"pmid": "4364763", "title": "Antiviral activity of cytarabine in herpesvirus-infected rats.", "content": "Antiviral activity of cytarabine in herpesvirus-infected rats. Intranasal inoculation of herpesvirus (approximately 1.8 mean lethal doses [LD(50)] in 0.1 ml) into 105- to 115-g rats produces paralytic disease in 4 to 5 days and 80 to 100% mortality in 8 to 12 days. Cytarabine (ara-C) (40 to 320 mg/kg), administered subcutaneously to inoculated rats, delays the onset of paralysis and protects the animals from death. Drug treatments were given twice daily for 5 days. Beneficial drug effects were observed even when initiation of therapy was delayed for 3 days after virus inoculation. A dose-response relationship existed when therapy was initiated at 4 h after virus inoculation. However, when therapy was delayed for 3 days, it appeared that the highest drug level (320 mg/kg twice daily) was somewhat less effective than the lower doses (160 and 80 mg/kg twice daily). Virus could be detected in homogenates of brain beginning 3 days after inoculation, and the titer increased through 7 days. Ara-C treatment, initiated 4 h after inoculation, caused a delay in the appearance of virus, and a reduction in the titer in the brain homogenates. No virus was detected in blood serum, or in homogenates prepared from lung, kidney, thymus, or spleen of infected rats. The virus titration studies are in agreement with the illness and mortality produced by herpesvirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364763"}
{"pmid": "4364764", "title": "Regulation of the diurnal rhythm of rat liver beta-hydroxy-beta-methylglutaryl coenzmye A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone.", "content": "Regulation of the diurnal rhythm of rat liver beta-hydroxy-beta-methylglutaryl coenzmye A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364764"}
{"pmid": "4364765", "title": "Thermodynamic relationships between the oxidation-reduction reactions and the ATP synthesis in suspensions of isolated pigeon heart mitochondria.", "content": "Thermodynamic relationships between the oxidation-reduction reactions and the ATP synthesis in suspensions of isolated pigeon heart mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364765"}
{"pmid": "4364766", "title": "Formation of the yeast mitochondrial membrane. 3. Accumulation of mitochondrial proteins synthesized in both the cytoplasm and mitochondria in yeast undergoing glucose depression.", "content": "Formation of the yeast mitochondrial membrane. 3. Accumulation of mitochondrial proteins synthesized in both the cytoplasm and mitochondria in yeast undergoing glucose depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364766"}
{"pmid": "4364767", "title": "The use of 13C spin lattice relaxation times to study the interaction of alpha-methyl-D-glucopyranoside with concanavalin A.", "content": "The use of 13C spin lattice relaxation times to study the interaction of alpha-methyl-D-glucopyranoside with concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364767"}
{"pmid": "4364768", "title": "Factors affecting the formation of phytol and its incorporation into chlorophyll by homogenates of the leaves of the french bean Phaseolus vulgaris.", "content": "Factors affecting the formation of phytol and its incorporation into chlorophyll by homogenates of the leaves of the french bean Phaseolus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364768"}
{"pmid": "4364770", "title": "Stimulation of the incorporation of 32Pi and myo-(2-3H)inositol into the phosphoinositides in polymorphonuclear leukocytes during phagocytosis.", "content": "Stimulation of the incorporation of 32Pi and myo-(2-3H)inositol into the phosphoinositides in polymorphonuclear leukocytes during phagocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364770"}
{"pmid": "4364771", "title": "Inhibition of nucleic acid synthesis in Ehrlich tumor cells by periodate-oxidized adenosine and adenylic acid.", "content": "Inhibition of nucleic acid synthesis in Ehrlich tumor cells by periodate-oxidized adenosine and adenylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364771"}
{"pmid": "4364769", "title": "Heme-heme interaction in cytochrome c oxidase: the cooperativity of the hemes of cytochrome c oxidase as evidenced in the reaction with CO.", "content": "Heme-heme interaction in cytochrome c oxidase: the cooperativity of the hemes of cytochrome c oxidase as evidenced in the reaction with CO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364769"}
{"pmid": "4364772", "title": "Ferrochelatase activity in wild-type and mutant strains of Spirillum itersonii. Solubilization with chaotropic reagents.", "content": "Ferrochelatase activity in wild-type and mutant strains of Spirillum itersonii. Solubilization with chaotropic reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364772"}
{"pmid": "4364774", "title": "New cyclopentenyl fatty acids in Flacourtiaceae. Straight-chain fatty acids and cyclic fatty acids in lipids during maturation of the seeds.", "content": "New cyclopentenyl fatty acids in Flacourtiaceae. Straight-chain fatty acids and cyclic fatty acids in lipids during maturation of the seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364774"}
{"pmid": "4364775", "title": "Adenosine diphosphate as a regulatory ligand in beef heart cytosol nucleoside diphosphokinase.", "content": "Adenosine diphosphate as a regulatory ligand in beef heart cytosol nucleoside diphosphokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364775"}
{"pmid": "4364776", "title": "Molecular characterization of proteins in detergent solutions.", "content": "Molecular characterization of proteins in detergent solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364776"}
{"pmid": "4364773", "title": "Alterations of the aryl hydrocarbon hydroxylase system during riboflavin depletion and repletion.", "content": "Alterations of the aryl hydrocarbon hydroxylase system during riboflavin depletion and repletion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364773"}
{"pmid": "4364780", "title": "Conformation of angiotensin II in aqueous solution. Titration of several peptide analogs and homologs.", "content": "Conformation of angiotensin II in aqueous solution. Titration of several peptide analogs and homologs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364780"}
{"pmid": "4364777", "title": "Effect of magnesium adenosine 5'-triphosphate on the accessibility of the iron of clostridial azoferredoxin, a component of nitrogenase.", "content": "Effect of magnesium adenosine 5'-triphosphate on the accessibility of the iron of clostridial azoferredoxin, a component of nitrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364777"}
{"pmid": "4364778", "title": "A convenient micro method for the quantitation of closed circular deoxyribonucleic acid.", "content": "A convenient micro method for the quantitation of closed circular deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364778"}
{"pmid": "4364779", "title": "Partial characterization of the sexual agglutination factor from Hansenula wingei Y-2340 type 5 cells.", "content": "Partial characterization of the sexual agglutination factor from Hansenula wingei Y-2340 type 5 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364779"}
{"pmid": "4364781", "title": "Bone turnover-sex hormone-parathyroid hormone interrelationships in postmenopausal osteoporosis.", "content": "Bone turnover-sex hormone-parathyroid hormone interrelationships in postmenopausal osteoporosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364781"}
{"pmid": "4364783", "title": "The mechanism of SV40 DNA replication.", "content": "The mechanism of SV40 DNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364783"}
{"pmid": "4364782", "title": "The temporal order of replication of some DNA cistrons.", "content": "The temporal order of replication of some DNA cistrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364782"}
{"pmid": "4364784", "title": "Replication of mitochondrial DNA: replicative forms of molecules from rat tissues and evidence for discontinuous replication.", "content": "Replication of mitochondrial DNA: replicative forms of molecules from rat tissues and evidence for discontinuous replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364784"}
{"pmid": "4364786", "title": "Genetic organization and regulation of the Drosophila Y chromosome.", "content": "Genetic organization and regulation of the Drosophila Y chromosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364786"}
{"pmid": "4364787", "title": "Recent DNA fiber diffraction studies and their implications for DNA recognition.", "content": "Recent DNA fiber diffraction studies and their implications for DNA recognition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364787"}
{"pmid": "4364788", "title": "Some properties of RNA:protein complexes from the nucleus of eukaryotic cells.", "content": "Some properties of RNA:protein complexes from the nucleus of eukaryotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364788"}
{"pmid": "4364785", "title": "Cleavage of mouse DNA by a restriction enzyme as a clue to the arrangement of genes.", "content": "Cleavage of mouse DNA by a restriction enzyme as a clue to the arrangement of genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364785"}
{"pmid": "4364790", "title": "A comparison of DNA binding proteins from normal and virus-transformed mouse cells.", "content": "A comparison of DNA binding proteins from normal and virus-transformed mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364790"}
{"pmid": "4364791", "title": "Intracerebral transplantation of human rhabdomyosarcoma cells into fetal and newborn kittens.", "content": "Intracerebral transplantation of human rhabdomyosarcoma cells into fetal and newborn kittens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364791"}
{"pmid": "4364792", "title": "Mammary tumor virus (MTV) antigens in normal and mammary tumor-bearing mice.", "content": "Mammary tumor virus (MTV) antigens in normal and mammary tumor-bearing mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364792"}
{"pmid": "4364793", "title": "Differences in cytochalasin B inhibition of 3-O-methylglucose uptake between BALB-3T3 cells and a murine sarcoma virus transformed clone.", "content": "Differences in cytochalasin B inhibition of 3-O-methylglucose uptake between BALB-3T3 cells and a murine sarcoma virus transformed clone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364793"}
{"pmid": "4364794", "title": "A study of herpes simplex type 2 antibody status in groups of patients with cervical neoplasia in Czechoslovakia.", "content": "A study of herpes simplex type 2 antibody status in groups of patients with cervical neoplasia in Czechoslovakia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364794"}
{"pmid": "4364796", "title": "Influence of interferon on virus particle formation in different oncornavirus carrier cell lines.", "content": "Influence of interferon on virus particle formation in different oncornavirus carrier cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364796"}
{"pmid": "4364797", "title": "Serum effects on cell-mediated destruction of Rous sarcomas.", "content": "Serum effects on cell-mediated destruction of Rous sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364797"}
{"pmid": "4364795", "title": "The humoral antibody response to a primary viral neoplasm (MSV) through its entire course in BALB-c mice.", "content": "The humoral antibody response to a primary viral neoplasm (MSV) through its entire course in BALB-c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364795"}
{"pmid": "4364799", "title": "The histogenesis of tumours induced in golden hamsters by murine sarcoma virus-Harvey (MSV-H).", "content": "The histogenesis of tumours induced in golden hamsters by murine sarcoma virus-Harvey (MSV-H).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364799"}
{"pmid": "4364800", "title": "Carcinogenicity of nitrosamines and methanesulphonate esters given intraperitoneally, in RF mice.", "content": "Carcinogenicity of nitrosamines and methanesulphonate esters given intraperitoneally, in RF mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364800"}
{"pmid": "4364798", "title": "Antibody to Epstein-Barr virus in man in Australia and New Guinea.", "content": "Antibody to Epstein-Barr virus in man in Australia and New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364798"}
{"pmid": "4364801", "title": "Cyclic-AMP in ocular tissues of the rabbit, monkey, and human.", "content": "Cyclic-AMP in ocular tissues of the rabbit, monkey, and human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364801"}
{"pmid": "4364802", "title": "Carbon-13 nuclear relaxation measurements in nicotinamide adenine dinucleotide and adenosine monophosphate.", "content": "Carbon-13 nuclear relaxation measurements in nicotinamide adenine dinucleotide and adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364802"}
{"pmid": "4364803", "title": "Kinetic studies of the reduction of ferricytochrome c by Fe(EDTA)2-.", "content": "Kinetic studies of the reduction of ferricytochrome c by Fe(EDTA)2-.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364803"}
{"pmid": "4364804", "title": "Effects of a prolonged 3-hour sleep-wake cycle on sleep stages, plasma cortisol, growth hormone and body temperature in man.", "content": "Effects of a prolonged 3-hour sleep-wake cycle on sleep stages, plasma cortisol, growth hormone and body temperature in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364804"}
{"pmid": "4364805", "title": "A rapid assay for 25-OH-vitamin D3 without preparative chromatography.", "content": "A rapid assay for 25-OH-vitamin D3 without preparative chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364805"}
{"pmid": "4364806", "title": "Oxytocin receptors in human uterus.", "content": "Oxytocin receptors in human uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364806"}
{"pmid": "4364808", "title": "Recovery of hypothalamic-pituitary-adrenal function, growth hormone responsiveness and sleep EEG pattern in a patient following removal of an adrenal cortical adenoma.", "content": "Recovery of hypothalamic-pituitary-adrenal function, growth hormone responsiveness and sleep EEG pattern in a patient following removal of an adrenal cortical adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364808"}
{"pmid": "4364807", "title": "A study of thyrotropin deficiencies by the combination of two tests of TSH function.", "content": "A study of thyrotropin deficiencies by the combination of two tests of TSH function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364807"}
{"pmid": "4364809", "title": "Hypothalamic-pituitary function in the olfacto-genital syndrome.", "content": "Hypothalamic-pituitary function in the olfacto-genital syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364809"}
{"pmid": "4364810", "title": "Multiple hormones in a bronchial tumor.", "content": "Multiple hormones in a bronchial tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364810"}
{"pmid": "4364811", "title": "Glandular end organ deficiency associated with secretion of biologically inactive pituitary peptides.", "content": "Glandular end organ deficiency associated with secretion of biologically inactive pituitary peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364811"}
{"pmid": "4364812", "title": "Prostaglandin E (PGE) control of cell proliferation in vitro: characteristics of HT-29.", "content": "Prostaglandin E (PGE) control of cell proliferation in vitro: characteristics of HT-29.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364812"}
{"pmid": "4364813", "title": "Editorial: The value of scanning in hepatic cirrhosis.", "content": "Editorial: The value of scanning in hepatic cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364813"}
{"pmid": "4364815", "title": "The agent of trachoma. Recent studies of the biology, biochemistry and immunology of a prokaryotic obligate parasite of eukaryocytes.", "content": "The agent of trachoma. Recent studies of the biology, biochemistry and immunology of a prokaryotic obligate parasite of eukaryocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364815"}
{"pmid": "4364817", "title": "In vitro and in vivo phosphorylation of myelin basic protein by cerebral protein kinase.", "content": "In vitro and in vivo phosphorylation of myelin basic protein by cerebral protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364817"}
{"pmid": "4364816", "title": "Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth.", "content": "Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364816"}
{"pmid": "4364818", "title": "Induced redistribution of membrane particles, anionic sites and con A receptors in Entamoeba histolytica.", "content": "Induced redistribution of membrane particles, anionic sites and con A receptors in Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364818"}
{"pmid": "4364819", "title": "Urinary excretion of carnitine in progressive muscular dystrophy.", "content": "Urinary excretion of carnitine in progressive muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364819"}
{"pmid": "4364821", "title": "Production of O2- in photolyzed water demonstrated through the use of superoxide dismutase.", "content": "Production of O2- in photolyzed water demonstrated through the use of superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364821"}
{"pmid": "4364820", "title": "Biologic exposure to dental materials.", "content": "Biologic exposure to dental materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364820"}
{"pmid": "4364822", "title": "Protein binding of 3',5'-adenosine cyclic monophosphate acid.", "content": "Protein binding of 3',5'-adenosine cyclic monophosphate acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364822"}
{"pmid": "4364824", "title": "Association of cowpea mosaic virus-induced double-stranded RNA with a cytopathological structure in infected cells.", "content": "Association of cowpea mosaic virus-induced double-stranded RNA with a cytopathological structure in infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364824"}
{"pmid": "4364823", "title": "Heterogeneity of the inner mitochondrial membrane through the unequal distribution of phospholipid unsaturation.", "content": "Heterogeneity of the inner mitochondrial membrane through the unequal distribution of phospholipid unsaturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364823"}
{"pmid": "4364825", "title": "A nonselective analysis of SV40 transformation of mouse 3T3 cells.", "content": "A nonselective analysis of SV40 transformation of mouse 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364825"}
{"pmid": "4364828", "title": "Characteristics of murine C-type viruses. II. The behavior of viruses resident in various cell lines and their hybrids on BALB-3T3 and mouse embryo fibroblast cultures.", "content": "Characteristics of murine C-type viruses. II. The behavior of viruses resident in various cell lines and their hybrids on BALB-3T3 and mouse embryo fibroblast cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364828"}
{"pmid": "4364827", "title": "Isolation of defective viruses from SV40-transformed human and hamster cells.", "content": "Isolation of defective viruses from SV40-transformed human and hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364827"}
{"pmid": "4364829", "title": "Maturation of vesicular stomatitis virus: electron microscopy of surface replicas of infected cells.", "content": "Maturation of vesicular stomatitis virus: electron microscopy of surface replicas of infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364829"}
{"pmid": "4364830", "title": "The involvement of NADH-cytochrome b5 reductase and cytochrome b5 complex in microsomal NADH-cytochrome c reductase activity. Resolution of the complex by triton X-100.", "content": "The involvement of NADH-cytochrome b5 reductase and cytochrome b5 complex in microsomal NADH-cytochrome c reductase activity. Resolution of the complex by triton X-100.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364830"}
{"pmid": "4364831", "title": "The involvement of NADH-cytochrome b5 reductase and cytochrome b5 complex in microsomal NADH-cytochrome c reductase activity. Changes in NADH-cytochrome c reductase activity following phenobarbital treatment.", "content": "The involvement of NADH-cytochrome b5 reductase and cytochrome b5 complex in microsomal NADH-cytochrome c reductase activity. Changes in NADH-cytochrome c reductase activity following phenobarbital treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364831"}
{"pmid": "4364826", "title": "Inhibition of influenza and parainfluenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA).", "content": "Inhibition of influenza and parainfluenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364826"}
{"pmid": "4364832", "title": "Labyrinthine morphology and temperature in cryosurgery (guinea pig).", "content": "Labyrinthine morphology and temperature in cryosurgery (guinea pig).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364832"}
{"pmid": "4364833", "title": "Isoleucyl transfer ribonucleic acid synthetase from Escherichia coli. Effect of limited cleavage by trypsin on activity and structure.", "content": "Isoleucyl transfer ribonucleic acid synthetase from Escherichia coli. Effect of limited cleavage by trypsin on activity and structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364833"}
{"pmid": "4364834", "title": "Fluorescence energy transfer between the thiamine diphosphate and flavine adenine dinucleotide binding sites on the pyruvate dehydrogenase multienzyme complex.", "content": "Fluorescence energy transfer between the thiamine diphosphate and flavine adenine dinucleotide binding sites on the pyruvate dehydrogenase multienzyme complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364834"}
{"pmid": "4364835", "title": "Fluorescent affinity labeling of initiation site on ribonucleic acid polymerase of Escherichia coli.", "content": "Fluorescent affinity labeling of initiation site on ribonucleic acid polymerase of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364835"}
{"pmid": "4364837", "title": "Conformational transitions of cyclic adenosine monophosphate receptor protein of Escherichia coli. A temperature-jump study.", "content": "Conformational transitions of cyclic adenosine monophosphate receptor protein of Escherichia coli. A temperature-jump study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364837"}
{"pmid": "4364836", "title": "Conformational transitions of cyclic adenosine monophosphate receptor protein of Escherichia coli. A fluorescent probe study.", "content": "Conformational transitions of cyclic adenosine monophosphate receptor protein of Escherichia coli. A fluorescent probe study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364836"}
{"pmid": "4364838", "title": "Interaction of apolipoprotein-alamine and apolipoprotein-glutamine-I with phosphatidylcholine. Effect on solute quenching of intrinsic fluorescence.", "content": "Interaction of apolipoprotein-alamine and apolipoprotein-glutamine-I with phosphatidylcholine. Effect on solute quenching of intrinsic fluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364838"}
{"pmid": "4364839", "title": "A new method of assay for polynucleotide ligase.", "content": "A new method of assay for polynucleotide ligase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364839"}
{"pmid": "4364840", "title": "Chemical synthesis of ppGpp.", "content": "Chemical synthesis of ppGpp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364840"}
{"pmid": "4364841", "title": "Serum lipoprotein apoproteins as major protein constituents of the human erythrocyte membrane.", "content": "Serum lipoprotein apoproteins as major protein constituents of the human erythrocyte membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364841"}
{"pmid": "4364843", "title": "Magnetic studies on the changes in the iron environment in Chromatium ferricytochrome c'.", "content": "Magnetic studies on the changes in the iron environment in Chromatium ferricytochrome c'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364843"}
{"pmid": "4364842", "title": "Effect of neuraminidase on the synthesis of collagen and other proteins.", "content": "Effect of neuraminidase on the synthesis of collagen and other proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364842"}
{"pmid": "4364844", "title": "A method for the preparation of desialylated human chorionic gonadotropin and its sub-units.", "content": "A method for the preparation of desialylated human chorionic gonadotropin and its sub-units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364844"}
{"pmid": "4364846", "title": "Aberrant carotid artery simulating a tumor of the middle ear.", "content": "Aberrant carotid artery simulating a tumor of the middle ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364846"}
{"pmid": "4364847", "title": "Effects of antibiotics on intracellular symbiotes in the pea aphid, Acyrthosiphon pisum.", "content": "Effects of antibiotics on intracellular symbiotes in the pea aphid, Acyrthosiphon pisum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364847"}
{"pmid": "4364849", "title": "A comparative ultrastructural study of the pars tuberalis of various mammals, the chicken and the newt.", "content": "A comparative ultrastructural study of the pars tuberalis of various mammals, the chicken and the newt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364849"}
{"pmid": "4364850", "title": "The cell-types in the adenohypophysis of the Indian catfish Heteropneustes fossilis (Bloch).", "content": "The cell-types in the adenohypophysis of the Indian catfish Heteropneustes fossilis (Bloch).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364850"}
{"pmid": "4364848", "title": "Fine structure of frog lime sacs.", "content": "Fine structure of frog lime sacs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364848"}
{"pmid": "4364853", "title": "Comparative studies on porcine and human high density lipoproteins.", "content": "Comparative studies on porcine and human high density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364853"}
{"pmid": "4364851", "title": "Intraependymal cerebrospinal fluid contacting neurons and axon terminals on the external surface in the filum terminale of the carp (Cyprinus carpio).", "content": "Intraependymal cerebrospinal fluid contacting neurons and axon terminals on the external surface in the filum terminale of the carp (Cyprinus carpio).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364851"}
{"pmid": "4364854", "title": "Characterization and quantification of a crustacean lipovitellin.", "content": "Characterization and quantification of a crustacean lipovitellin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364854"}
{"pmid": "4364855", "title": "Some enzymic reactions of adenine derivatives in the tail muscle of the lobster, Homarus americanus.", "content": "Some enzymic reactions of adenine derivatives in the tail muscle of the lobster, Homarus americanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364855"}
{"pmid": "4364852", "title": "The fine structure of the digital pads of rhacophorid tree frogs.", "content": "The fine structure of the digital pads of rhacophorid tree frogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364852"}
{"pmid": "4364856", "title": "Fish liver fructose 1,6-diphosphatase. II. \"Neutral\" and \"alkaline\" forms.", "content": "Fish liver fructose 1,6-diphosphatase. II. \"Neutral\" and \"alkaline\" forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364856"}
{"pmid": "4364858", "title": "DNCB reactivity in patients with skin carcinoma.", "content": "DNCB reactivity in patients with skin carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364858"}
{"pmid": "4364857", "title": "The amino acid sequence of ostrich (Struthio camelus) cytochrome c.", "content": "The amino acid sequence of ostrich (Struthio camelus) cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364857"}
{"pmid": "4364860", "title": "Modulation of mitochondrial adenylate kinase by citric-acid-cycle intermediates.", "content": "Modulation of mitochondrial adenylate kinase by citric-acid-cycle intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364860"}
{"pmid": "4364861", "title": "The effect of lanthanide ions on the conformation of adenine mononucleotides and dinucleotides.", "content": "The effect of lanthanide ions on the conformation of adenine mononucleotides and dinucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364861"}
{"pmid": "4364862", "title": "Characterization of the single-strand-specific nuclease S1 activity on double-stranded supercoiled polyoma DNA.", "content": "Characterization of the single-strand-specific nuclease S1 activity on double-stranded supercoiled polyoma DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364862"}
{"pmid": "4364863", "title": "Structural studies on phenylalanine transfer ribonucleic acid from yeast with the spectroscopic label formycin.", "content": "Structural studies on phenylalanine transfer ribonucleic acid from yeast with the spectroscopic label formycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364863"}
{"pmid": "4364864", "title": "Intracellular cyclic AMP level and intestinal smooth muscle relaxation.", "content": "Intracellular cyclic AMP level and intestinal smooth muscle relaxation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364864"}
{"pmid": "4364866", "title": "Chromosomal and nonchromosomal mutations affecting the \"killer character\" of Saccharomyces cerevisiae.", "content": "Chromosomal and nonchromosomal mutations affecting the \"killer character\" of Saccharomyces cerevisiae. The \"killer character\" of Saccharomyces cerevisiae is a nonchromosomal genetic element which imparts to cells carrying it (a) the ability to kill cells which lack it, by secreting the soluble macromolecular killer substance and (b) the ability to resist the killing effects of the killer substance.-Mutants have been isolated from S. cerevisiae carrying the \"killer character\". Mutants were found in two nuclear genes (mak1 and mak2) involved in maintenance of the genetic element of the killer character. Mutants in three other nuclear genes could maintain the cytoplasmic genetic element normally; two of these were able to express resistance to killing, but not the ability to kill (kex1 and kex2), while the third could express the killing function, but was sensitive to killing and is thus a \"suicide\" strain (rex1). These five nuclear genes were all distinct.-Several mutants were detected which showed non-mendelian segregation indicating mutation of the \"cytoplasmic\" genetic element. Some such mutants had normal resistance to killing but were either unable to kill at all or showed marked reduction in the ability to kill. Others had lost both killing ability and resistance. None were suppressive.-Two nonkilling mutants, both of which showed cytoplasmic inheritance, were mated. A large, but variable, proportion of diploid colonies, plated after several generations of growth, showed normal killing which has then stably inherited on further subcloning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364866"}
{"pmid": "4364865", "title": "Interactions between peripheral and hypothalamic carbachol stimulation of drinking in the rat.", "content": "Interactions between peripheral and hypothalamic carbachol stimulation of drinking in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364865"}
{"pmid": "4364867", "title": "Phosphatases within the cartilage of the mandibular condyle of the mouse.", "content": "Phosphatases within the cartilage of the mandibular condyle of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364867"}
{"pmid": "4364868", "title": "Proceedings: The effect of cyclic AMP and cyclic GMP on the histology of the neonatal rat hepatocytes.", "content": "Proceedings: The effect of cyclic AMP and cyclic GMP on the histology of the neonatal rat hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364868"}
{"pmid": "4364869", "title": "Proceedings: Evidence that large granular vesicles are not involved in transmitter release from adrenergic nerves.", "content": "Proceedings: Evidence that large granular vesicles are not involved in transmitter release from adrenergic nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364869"}
{"pmid": "4364870", "title": "Proceedings: Adrenergic and cholinergic innervation of arteriovenous anastomoses: the effect of 6-hydroxydopamine.", "content": "Proceedings: Adrenergic and cholinergic innervation of arteriovenous anastomoses: the effect of 6-hydroxydopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364870"}
{"pmid": "4364872", "title": "The rapid isolation of plant virus RNAs using sodium perchlorate.", "content": "The rapid isolation of plant virus RNAs using sodium perchlorate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364872"}
{"pmid": "4364873", "title": "Human serum lipoproteins as inhibitors of haemagglutination for selected togaviruses.", "content": "Human serum lipoproteins as inhibitors of haemagglutination for selected togaviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364873"}
{"pmid": "4364874", "title": "Studies in genetic resistance to RSV (RAV-O). A third type of genetic resistance typified by the W line of fowl and further support for the two loci genetic model.", "content": "Studies in genetic resistance to RSV (RAV-O). A third type of genetic resistance typified by the W line of fowl and further support for the two loci genetic model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364874"}
{"pmid": "4364871", "title": "Proceedings: Interrelationship between swimming performance and chronological age, dental age, skeletal age of age group competitive swimmers.", "content": "Proceedings: Interrelationship between swimming performance and chronological age, dental age, skeletal age of age group competitive swimmers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364871"}
{"pmid": "4364875", "title": "On the nature of poliovirus genetic recombinants.", "content": "On the nature of poliovirus genetic recombinants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364875"}
{"pmid": "4364876", "title": "Retarded growth of poliovirus in contact inhibited cells.", "content": "Retarded growth of poliovirus in contact inhibited cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364876"}
{"pmid": "4364877", "title": "A temperature-sensitive mutant of vesicular stomatitis virus with two abnormal virus proteins.", "content": "A temperature-sensitive mutant of vesicular stomatitis virus with two abnormal virus proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364877"}
{"pmid": "4364878", "title": "Bovine enterovirus-1: characterization, replication and cytopathogenic effects.", "content": "Bovine enterovirus-1: characterization, replication and cytopathogenic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364878"}
{"pmid": "4364880", "title": "The effect of an antireceptor serum on mammalian cell lines.", "content": "The effect of an antireceptor serum on mammalian cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364880"}
{"pmid": "4364879", "title": "Murine sarcoma virus-induced cytopathological effects in mouse cells made resistant to 6-azauridine.", "content": "Murine sarcoma virus-induced cytopathological effects in mouse cells made resistant to 6-azauridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364879"}
{"pmid": "4364881", "title": "A locus affecting circulating interferon levels induced by mouse mammary tumour virus.", "content": "A locus affecting circulating interferon levels induced by mouse mammary tumour virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364881"}
{"pmid": "4364882", "title": "Association of foot-and-mouth disease virus replicase with RNA template and cytoplasmic membranes.", "content": "Association of foot-and-mouth disease virus replicase with RNA template and cytoplasmic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364882"}
{"pmid": "4364883", "title": "A stable syncytial mutant of herpes simplex type 2 virus.", "content": "A stable syncytial mutant of herpes simplex type 2 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364883"}
{"pmid": "4364885", "title": "Heparin anticoagulation as adjuvant to chemotherapy in carcinoma of the lung.", "content": "Heparin anticoagulation as adjuvant to chemotherapy in carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364885"}
{"pmid": "4364887", "title": "Potential of yttrium-aluminum-garnet laser in caries prevention.", "content": "Potential of yttrium-aluminum-garnet laser in caries prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364887"}
{"pmid": "4364886", "title": "Effects of sodium warfarin and other carcinostatic agents on malignant cells: a study of drug synergy.", "content": "Effects of sodium warfarin and other carcinostatic agents on malignant cells: a study of drug synergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364886"}
{"pmid": "4364894", "title": "Ribonucleotides linked to DNA of herpes simplex virus type 1.", "content": "Ribonucleotides linked to DNA of herpes simplex virus type 1. Cells of a continuous cell line derived from rabbit embryo fibroblasts were infected with herpes simplex type 1 virus (HSV-1) and maintained in the presence of either [5-(3)H]uridine or [methyl-(3)H]thymidine or (32)PO(4) (3-). Nucleocapsids were isolated from the cytoplasmic fraction, partially purified, and treated with DNase and RNase. From the pelleted nucleocapsids, DNA was extracted and purified by centrifugation in sucrose and cesium sulfate gradients. The acid-precipitable radioactivity of [5-(3)H]uridine-labeled DNA was partially susceptible to pancreatic RNase and alkaline treatment; the susceptibility to the enzyme decreased with increasing salt concentration. No drop of activity of DNA labeled with [(3)H]thymidine was observed either after RNase or alkali treatment. Base composition analysis of [5-(3)H]uridine-labeled DNA showed that the radioactivity was recovered as uracil and cytosine. In the cesium sulfate gradient, the purified [5-(3)H]uridine-labeled DNA banded at the same position as the (32)P-labeled DNA. The present data tend to suggest that ribonucleotide sequences are present in HSV DNA, that they are covalently attached to the viral DNA, and that they can form double-stranded structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364894"}
{"pmid": "4364896", "title": "Immunochemical characterization of two major polypeptides from murine mammary tumor virus.", "content": "Immunochemical characterization of two major polypeptides from murine mammary tumor virus. A major murine mammary tumor viral (MMTV) antigen, sl, originally described by Nowinski et al. (1967, 1968, 1971), has been purified from RIII mouse milk MMTV by sequential ion-exchange and gel chromatography. The purified protein with sl antigenic reactivity contains carbohydrate, and has an apparent minimal molecular weight of 52,000. It can be designated as gp52 (sl). Another major MMTV viral protein with a molecular weight of 27,000 has also been isolated, and antisera have been prepared against it. Both MMTV gp52 (sl) and p27 viral polypeptides have been iodinated with (125)I and used in immunoprecipitation and competition assays. The two MMTV proteins differ absolutely from each other and from major mouse type C viral polypeptides in molecular weight, immunological reactivity, and amino acid composition. Purified gp52 (sl) in radioimmunoprecipitation inhibition assays reacted in two distinct patterns. One pattern showed partial displacement of antibody which could be converted to the second, a complete displacement, by heating the antigen, presumably by exposing additional reactive determinants. Biologically, the patterns of major MMTV polypeptide expression in milk correlated with spontaneous mammary tumor incidence in different strains of mice, indicating that the sl antigen is group specific for MMTV or that several mouse strains contain the same virus type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364896"}
{"pmid": "4364897", "title": "Harvey sarcoma virus: a second murine type C sarcoma virus with rat genetic information.", "content": "Harvey sarcoma virus: a second murine type C sarcoma virus with rat genetic information. The nucleic acid sequences found in the Harvey strain of murine sarcoma virus have been analyzed by RNA.[(3)H]DNA and [(3)H]RNA.DNA hybridization techniques. The Harvey strain of murine sarcoma virus has been found to possess at least two sets of nucleic acid sequences. One set of sequences is contained in the Moloney strain of mouse type-C virus, and the other set is contained in DNA transcripts synthesized in endogenous reactions containing rat type-C virus(es). The nucleic acid sequences that are detected in the Harvey sarcoma virus with the DNA probes synthesized from the rat type-C virus(es) are related to the rat sequences detected in the Kirsten strain of murine sarcoma virus. The results support the model that both Kirsten and Harvey sarcoma viruses arose through a process of recombination or reassortment between mouse type-C viruses and sequences in rat cells and suggest that the information for transformation of fibroblasts may be contained in the rat type-C or cellular genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364897"}
{"pmid": "4364898", "title": "Conditional lethal mutants of adenovirus 2-simian virus 40 hybrids. I. Host range mutants of Ad2+ND1.", "content": "Conditional lethal mutants of adenovirus 2-simian virus 40 hybrids. I. Host range mutants of Ad2+ND1. Human adenovirus type 2 (Ad2) grows poorly in monkey cells, although this defect can be overcome by co-infection with simian virus 40 (SV40). The nondefective Ad2-SV40 hybrid virus, Ad2(+)ND1, replicates efficiently in both human and African green monkey kidney cells, presumably due to the insertion of SV40 sequences into the Ad2 DNA. Several mutants of Ad2(+)ND1 have been isolated that grow and plaque poorly in monkey cells, although they retain the ability to replicate and plaque efficiently in HeLa cells. One of these mutants (H39) has been examined in detail. Studies comparing the DNA of the mutant with Ad2(+)ND1 either by the cleavage patterns produced by Escherichia coli R.RI restriction endonuclease digestion or by heteroduplexing reveal no differences. The pattern of protein synthesis of Ad2(+)ND1 and H39 in monkey cells is quite different with the mutant resembling Ad2, which is defective in the synthesis of late proteins. However, in human cells, the proteins synthesized by H39 and the parent Ad2(+)ND1 are very similar. The production of SV40 U antigen in H39-infected cells is different from that in Ad2(+)ND1-infected cells. Finally, the growth of H39 in monkey cells can be complemented by SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364898"}
{"pmid": "4364895", "title": "Inhibition of the multiplication of vesicular stomatitis and Newcastle disease virus by 2-deoxy-d-glucose.", "content": "Inhibition of the multiplication of vesicular stomatitis and Newcastle disease virus by 2-deoxy-d-glucose. The production of infectious vesicular stomatitis (VSV) and Newcastle disease virus can be completely inhibited by 2-deoxy-d-glucose in pyruvate-containing medium, if virus either grown in pyruvate-containing medium or dialyzed against phosphate-buffered saline is used for infection. Under these conditions, the synthesis of all VSV proteins is reduced. VSV RNA, which is synthesized at reduced rates, seems to be unstable. The effect is completely reversible. If virus grown in glucose-containing medium is used for infection, the production of both viruses is not significantly inhibited by 2-deoxy-d-glucose. Under these conditions the production of the VSV glycoprotein is specifically impaired, but does not lead to a marked reduction of the yield of infectious virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364895"}
{"pmid": "4364899", "title": "Virion-bound protein kinase in Semliki forest and Sindbis viruses.", "content": "Virion-bound protein kinase in Semliki forest and Sindbis viruses. Semliki forest virus and Sindbis virus (Alphaviruses belonging to the togavirus group) grown in BHK-21 cells possessed very low levels of virion-associated protein kinase activity. For comparison, vesicular stomatitis virus, also grown in BHK-21 cells, contained a virion-bound protein kinase which had a specific activity 80 times greater than that of the Alphaviruses. The Alphavirus protein kinase was unmasked by the nonionic detergent Nonidet P-40 but was not activated by cyclic nucleotides. Phosvitin was the best exogenous phosphate acceptor for assaying the viral enzyme in vitro. Phosphoprotein phosphatase activity was also detected in the Alphaviruses. Both in vivo and in vitro, all of the viral structural polypeptides were phosphorylated, and the phosphorylated amino acids were found to be serine and threonine. The viral nucleocapsid protein was about four times more efficient as a phosphate acceptor than were the envelope proteins. From 33 to 50% of the total protein kinase was bound to the viral nucleocapsid, and the specific activity of this enzyme was 4 to 10 times greater than that associated with the viral envelope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364899"}
{"pmid": "4364901", "title": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. Transformation of hamster kidney cells by adenovirus 2 and the nondefective hybrid viruses.", "content": "Studies of nondefective adenovirus 2-simian virus 40 hybrid viruses. Transformation of hamster kidney cells by adenovirus 2 and the nondefective hybrid viruses. Nonhybrid adenovirus 2 (Ad2) and five nondefective Ad2-simian virus 40 (SV40) hybrids (Ad2(+)ND(1)-Ad2(+)ND(5)) failed to produce tumors when injected into newborn hamsters. However, each of these agents transformed hamster kidney cells in vitro, and the transformed cell lines produced tumors when injected into suckling hamsters. Foci of cells transformed by the hybrids could not be distinguished from foci of cells transformed by nonhybrid Ad2. Histopathologically, tumors induced by the nondefective hybrid-transformed lines were of the adenovirus type with no areas of SV40-type fibrosarcoma. All of the cell lines studied contained Ad2 T antigen and Ad2 RNA. Only the B55HK(1) line contained the three early SV40 antigens, U, TSTA, and T. The ND(4)HK(1) line contained SV40 T and TSTA antigens (the latter antigen being detected only after 48 to 49 tissue culture passages) and SV40 RNA. The ND(2)HK(2) line contained SV40 RNA but no detectable SV40 antigens; the other hybrid-transformed lines contained no SV40 RNA. The transformation of hamster cells by the nondefective Ad2-SV40 hybrids seemed to be caused by the Ad2 genome and could not be attributed to the regions of the SV40 genome contained within the hybrids. Additionally, these results indicate that interactions between the genomes of the nondefective hybrid viruses and the hamster cells they transform are complex and could involve the site of integration, the size of the incorporated viral genome, the transcription or translation of the viral genome, or various combinations of these processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364901"}
{"pmid": "4364902", "title": "Virion-associated RNA primer for Rous sarcoma virus DNA synthesis: isolation from uninfected cells.", "content": "Virion-associated RNA primer for Rous sarcoma virus DNA synthesis: isolation from uninfected cells. Uninfected chicken, duck, rat, and human fibroblast cells in culture contained a tRNA-like RNA molecule which was structurally identical to a virion-associated RNA primer for in vitro Rous sarcoma virus DNA synthesis. This primer RNA appeared to be a normal tRNA of these cells. It was not found in a number of lower eukaryotic cells or in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364902"}
{"pmid": "4364904", "title": "Endogenous C-type virus of a mouse cell line and its defectiveness.", "content": "Endogenous C-type virus of a mouse cell line and its defectiveness. MLg cells originating from a newborn ddY mouse began to release C-type virus by treatment with 5-iodo-2'-deoxyuridine (5 mug/ml) for 48 h, or spontaneoulsy after prolonged cultivation. The data indicated the presence of three categories of the viruses spontaneously induced, i.e., virus equipped with the abilities of infecting and transforming the S+L- C182 cells, virus which can infect C182 cells but is unable to transform C182 cells, and virus which cannot infect nor transform the C182 cells, but is positive for the XC test. The type of the virus produced depended upon the cell clone. With the advance in the passage level, the cell population was dominated by the cells producing, uniquely, the last category of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364904"}
{"pmid": "4364900", "title": "Simian virus 40 transcription in productively infected and transformed cells.", "content": "Simian virus 40 transcription in productively infected and transformed cells. Several independent cell lines transformed by simian virus 40 carry a species of viral RNA of 900,000 to 1,000,000 daltons. A viral RNA species of similar size is found early in the lytic cycle. Late in the viral lytic cycle, two prominent viral RNA species of about 600,000 and 900,000 daltons are seen. The larger late species shares nucleotide sequences with, and is less stable than, the smaller. These RNA species are located in the cytoplasm of the infected cell. The regions of the viral genome coding for these RNA species are mapped by hybridization of lytic RNA species to fragments of the genome produced by cleavage with Haemophilus aegyptius endonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364900"}
{"pmid": "4364905", "title": "Cellular replication and the persistence of inducible RNA type C viruses.", "content": "Cellular replication and the persistence of inducible RNA type C viruses. Cells of mouse and rat origin contain endogenous type C viruses. There are intrinsic regulatory factors which restrict the ability of different classes of these inducible viruses to persist in cells after chemical activation. The cellular block to certain viruses is shown to be overcome under conditions in which the virus-activated cells are allowed continued exponential growth. These findings may help to explain the high frequency at which replicating type C viruses are detectable in naturally occurring tumors of some species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364905"}
{"pmid": "4364903", "title": "Inactivation of herpes simplex virus by concanavalin A.", "content": "Inactivation of herpes simplex virus by concanavalin A. The infectivity of herpes simplex virus type 1 (HSV-1) was inactivated after treatment with either concanavalin A (ConA) or periodate. Phytohemagglutinin, wheat germ agglutinin, pokeweed mitogen, and neuraminidase failed to inactivate the virus. The effect of ConA could be specifically inhibited or reversed by the addition of alpha-methyl-d-glucoside or alpha-methyl-d-mannoside. Evidence was obtained that HSV-1 inactivated by ConA could adsorb to host cells. Viral aggregation was not a major mechanism in the inactivation of HSV-1 by ConA. Under the experimental conditions employed, inactivation of HSV-1 was faster by ConA than by antiserum and less temperature dependent. A ConA-resistant fraction was detected which appeared to adsorb less quickly than untreated virus, and penetration of ConA-resistant fraction was strikingly slow. The presence of aggregates in the virus preparation did not appear to account for the ConA-resistant fraction. Inactivation of viral infectivity by ConA was obtained only with enveloped viruses, since HSV-1, HSV-2, pseudorabies, and vesicular stomatitis virus were inactivated and vaccinia and echovirus type 6 were not.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364903"}
{"pmid": "4364907", "title": "Ocular myopathy. A case history with electron microscopy, biochemistry and review of literature.", "content": "Ocular myopathy. A case history with electron microscopy, biochemistry and review of literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364907"}
{"pmid": "4364909", "title": "Effect of cyclic AMP and some structural analogues on the dark repair inhibition by caffeine of uv-irradiated cells.", "content": "Effect of cyclic AMP and some structural analogues on the dark repair inhibition by caffeine of uv-irradiated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364909"}
{"pmid": "4364922", "title": "Effects of vestibular nuclei lesions on vestibulo-ocular reflexes and posture in monkeys.", "content": "Effects of vestibular nuclei lesions on vestibulo-ocular reflexes and posture in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364922"}
{"pmid": "4364923", "title": "Spindle responses in pig eye muscles.", "content": "Spindle responses in pig eye muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364923"}
{"pmid": "4364925", "title": "Focal nodular hyperplasia of the liver. Possible relationship to oral contraceptives.", "content": "Focal nodular hyperplasia of the liver. Possible relationship to oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364925"}
{"pmid": "4364927", "title": "Letter: Ferruginous bodies in lung tissue.", "content": "Letter: Ferruginous bodies in lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364927"}
{"pmid": "4364926", "title": "Ten thousand consecutive frozen sections. A retrospective study focusing on accuracy and quality control.", "content": "Ten thousand consecutive frozen sections. A retrospective study focusing on accuracy and quality control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364926"}
{"pmid": "4364924", "title": "The mechanism of interaction of red cell organic phosphates with hemoglobin.", "content": "The mechanism of interaction of red cell organic phosphates with hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364924"}
{"pmid": "4364929", "title": "Congenital band of the abdomen and the amniotic etiology of bands.", "content": "Congenital band of the abdomen and the amniotic etiology of bands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364929"}
{"pmid": "4364928", "title": "Colitis cystica profunda.", "content": "Colitis cystica profunda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364928"}
{"pmid": "4364930", "title": "Serum lipids and lipoproteins in hepatosis of pregnancy and pre-eclampsia.", "content": "Serum lipids and lipoproteins in hepatosis of pregnancy and pre-eclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364930"}
{"pmid": "4364931", "title": "Rapid ACTH test with plasma aldosterone levels. Improved diagnostic discrimination.", "content": "Rapid ACTH test with plasma aldosterone levels. Improved diagnostic discrimination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364931"}
{"pmid": "4364932", "title": "Diagnostic use of glucagon-induced insulin response. Studies in patients with insulinoma or other hypoglycemic conditions.", "content": "Diagnostic use of glucagon-induced insulin response. Studies in patients with insulinoma or other hypoglycemic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364932"}
{"pmid": "4364934", "title": "Vincristine neurotoxicity.", "content": "Vincristine neurotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364934"}
{"pmid": "4364935", "title": "Letter: \"Swiss-cheese\" platelets.", "content": "Letter: \"Swiss-cheese\" platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364935"}
{"pmid": "4364933", "title": "Goltz syndrome with multiple giant-cell tumor-like lesions in bones. A case report.", "content": "Goltz syndrome with multiple giant-cell tumor-like lesions in bones. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364933"}
{"pmid": "4364937", "title": "Susceptibility of herpesviruses to cytosine arabinoside: standardization of susceptibility test procedure and relative resistance of herpes simplex type 2 strains.", "content": "Susceptibility of herpesviruses to cytosine arabinoside: standardization of susceptibility test procedure and relative resistance of herpes simplex type 2 strains. Susceptibility testing of herpes simplex type 1 (HSV-1) and type 2 (HSV-2) viruses to cytosine arabinoside (Ara-C) has been standardized under conditions of optimal reproducibility, susceptibility, and simplicity. Standard conditions were defined as virus inoculum of 10(1.5) to 10(2.5) TCID(50), WI-38 strain of lung fibroblasts, 2-day incubation, and observation of virus cytopathic effect after staining by the May-Greenwald-Giemsa method. The variability of minimum inhibitory concentration (MIC) of cytopathic effect was fourfold within each test and sixfold in successive assays. MIC values of all seven tested HSV-1 strains were in the range of 0.25 to 0.75 mug per ml, whereas four of nine HSV-2 strains had MIC values of 0.9 mug per ml and greater. A similar method can be used for assay of virus inhibitory titers of body fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364937"}
{"pmid": "4364936", "title": "Letter: Gastrin and islet-cell tumors.", "content": "Letter: Gastrin and islet-cell tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364936"}
{"pmid": "4364939", "title": "Analysis of 2-acetylaminofluorene: residues in laboratory chow and microbiological media.", "content": "Analysis of 2-acetylaminofluorene: residues in laboratory chow and microbiological media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364939"}
{"pmid": "4364940", "title": "A monomolecular electron transfer chain: structure and function of cytochrome C3.", "content": "A monomolecular electron transfer chain: structure and function of cytochrome C3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364940"}
{"pmid": "4364938", "title": "Lividomycin resistance in staphylococci by enzymatic phosphorylation.", "content": "Lividomycin resistance in staphylococci by enzymatic phosphorylation. Enzymatic inactivation of lividomycin (LV) was attempted with nine clinical isolates of staphylococci including LV-susceptible and -resistant strains. LV inactivation and the incorporation into LV of (32)P from gamma-(32)P-adenosine triphosphate were demonstrated in the presence of cell-free extracts from LV-resistant strains but not from LV-susceptible ones. The enzyme was purified approximately 82-fold from a resistant Staphylococcus aureus strain by means of ammonium sulfate fractionation and column chromatography. Some properties of the partially purified LV-phosphorylating enzyme were quite similar to those of an enzyme from Escherichia coli carrying an R factor conferring LV resistance, and the phosphorylated product of the drug was also found to be identical with that produced by E. coli carrying an R factor, i.e., 5''-phosphoryl-LV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364938"}
{"pmid": "4364941", "title": "The variable course of primary hepatocellular carcinoma.", "content": "The variable course of primary hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364941"}
{"pmid": "4364942", "title": "Sleep and delirium after open heart surgery.", "content": "Sleep and delirium after open heart surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364942"}
{"pmid": "4364943", "title": "Growth pattern and dietary intake of children with chronic renal insufficiency.", "content": "Growth pattern and dietary intake of children with chronic renal insufficiency. The growth pattern and dietary intake of 33 children with varying degrees of renal insufficiency has been investigated. The development of impaired renal function in infancy has a more deleterious effect on linear growth than has its onset in later years. A reduction in growth velocity may occur once the glomerular filtration rate falls below 25 ml/min/1.73m(2). There was a significant reduction of the energy, protein, and vitamin D intakes of children with renal insufficiency compared with those recommended for their age, and of energy intake compared with that of normal children of their own height. Reduced growth velocity occurred when energy intake fell below 80% of that recommended. The reduction in the intake of energy and nutrients in these children may in part be responsible for their growth retardation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364943"}
{"pmid": "4364944", "title": "Viability and pathogenicity of entomogenous fungi after prolonged storage on silica gel at -20degrees C.", "content": "Viability and pathogenicity of entomogenous fungi after prolonged storage on silica gel at -20degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364944"}
{"pmid": "4364945", "title": "Corynebacterium okanaganae, an entomopathogenic species of the Corynebacteriaceae.", "content": "Corynebacterium okanaganae, an entomopathogenic species of the Corynebacteriaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364945"}
{"pmid": "4364948", "title": "Primary tumours of salivary glands: analysis of 111 tumours.", "content": "Primary tumours of salivary glands: analysis of 111 tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364948"}
{"pmid": "4364949", "title": "Conformational flexibility of the neurohypophyseal hormones oxytocin and lysine-vasopressin. A carbon-13 spin-lattice relaxation study of backbone and side chains.", "content": "Conformational flexibility of the neurohypophyseal hormones oxytocin and lysine-vasopressin. A carbon-13 spin-lattice relaxation study of backbone and side chains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364949"}
{"pmid": "4364952", "title": "Alteration of rabbit PCA reaction by drugs known to influence intracellular cyclic AMP.", "content": "Alteration of rabbit PCA reaction by drugs known to influence intracellular cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364952"}
{"pmid": "4364951", "title": "Role of cyclic adenosine 3',5'-monophosphate in lymphocyte mitogenesis.", "content": "Role of cyclic adenosine 3',5'-monophosphate in lymphocyte mitogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364951"}
{"pmid": "4364953", "title": "Spin-label studies of a hapten-combining site of rainbow trout antibody.", "content": "Spin-label studies of a hapten-combining site of rainbow trout antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364953"}
{"pmid": "4364954", "title": "Properties of antisera to ganglioside GM1 and asialo GM1.", "content": "Properties of antisera to ganglioside GM1 and asialo GM1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364954"}
{"pmid": "4364956", "title": "The variability of plasma oestradiol concentration in late pregnancy.", "content": "The variability of plasma oestradiol concentration in late pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364956"}
{"pmid": "4364955", "title": "Increase in Gross (G) antigen sites on the surface of AKR virus-induced rat lymphoma cells after treatment with trypsin.", "content": "Increase in Gross (G) antigen sites on the surface of AKR virus-induced rat lymphoma cells after treatment with trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364955"}
{"pmid": "4364957", "title": "Adrenal response in pregnancy to long-acting tetracosactrin.", "content": "Adrenal response in pregnancy to long-acting tetracosactrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364957"}
{"pmid": "4364958", "title": "An evaluation of cytology in the diagnosis of herpes simplex virus infection and cytomegalovirus infection of the cervix uteri.", "content": "An evaluation of cytology in the diagnosis of herpes simplex virus infection and cytomegalovirus infection of the cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364958"}
{"pmid": "4364962", "title": "Synovial sarcoma of the cervical area.", "content": "Synovial sarcoma of the cervical area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364962"}
{"pmid": "4364967", "title": "The cytidine mechanism and methylation pathway in the formation of N-methylated ethanolamine phosphoglycerides in Neurospora crassa.", "content": "The cytidine mechanism and methylation pathway in the formation of N-methylated ethanolamine phosphoglycerides in Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364967"}
{"pmid": "4364968", "title": "Letter: On the repression of mitochondrial DNA transcription by fructose 1.6-diphosphate and its derepression by cyclic adenosine 3',5'-monophosphate.", "content": "Letter: On the repression of mitochondrial DNA transcription by fructose 1.6-diphosphate and its derepression by cyclic adenosine 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364968"}
{"pmid": "4364969", "title": "Wilms's tumor in three children of a woman with congenital hemihypertrophy.", "content": "Wilms's tumor in three children of a woman with congenital hemihypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364969"}
{"pmid": "4364966", "title": "Differential labeling of triglycerides and polar lipids of cultured mammalian cells by albumin-bound (1-14C) fatty acids of serum.", "content": "Differential labeling of triglycerides and polar lipids of cultured mammalian cells by albumin-bound (1-14C) fatty acids of serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364966"}
{"pmid": "4364972", "title": "Multiple denticle formation.", "content": "Multiple denticle formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364972"}
{"pmid": "4364971", "title": "Jaw metastases.", "content": "Jaw metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364971"}
{"pmid": "4364973", "title": "A preview of growth hormone stimulation tests in children.", "content": "A preview of growth hormone stimulation tests in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364973"}
{"pmid": "4364976", "title": "Tumor detection and localization with 99mTc-tetracycline.", "content": "Tumor detection and localization with 99mTc-tetracycline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364976"}
{"pmid": "4364975", "title": "Limitations of angiography and scanning in diagnosis of liver masses.", "content": "Limitations of angiography and scanning in diagnosis of liver masses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364975"}
{"pmid": "4364978", "title": "Studies on the mechanism of fructose-induced hyperuricemia in man.", "content": "Studies on the mechanism of fructose-induced hyperuricemia in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364978"}
{"pmid": "4364979", "title": "Observations of altered intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human disease.", "content": "Observations of altered intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364979"}
{"pmid": "4364981", "title": "Electrophoretic separation of normal and mutant phosphoribosylpyrophosphate synthetase.", "content": "Electrophoretic separation of normal and mutant phosphoribosylpyrophosphate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364981"}
{"pmid": "4364980", "title": "Human erythrocyte phosphoribosylpyrophosphate content and \"generation\" during a constant rate infusion of xylitol.", "content": "Human erythrocyte phosphoribosylpyrophosphate content and \"generation\" during a constant rate infusion of xylitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364980"}
{"pmid": "4364982", "title": "Diagnostic value of Bekesy comfortable loudness tracings.", "content": "Diagnostic value of Bekesy comfortable loudness tracings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364982"}
{"pmid": "4364984", "title": "Malignant fibrous histiocytoma of the maxilla. A report of an unusual lesion.", "content": "Malignant fibrous histiocytoma of the maxilla. A report of an unusual lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364984"}
{"pmid": "4364983", "title": "Glomus tympanicum tumor in infancy.", "content": "Glomus tympanicum tumor in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364983"}
{"pmid": "4364985", "title": "Chemical, biochemical and toxicological differences between carbon tetrachloride and chloroform. A critical review of recent investigations of these compounds in mammals.", "content": "Chemical, biochemical and toxicological differences between carbon tetrachloride and chloroform. A critical review of recent investigations of these compounds in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364985"}
{"pmid": "4364986", "title": "ATP balance and the effect of 2,4-dinitrophenol on fatty acid synthesis.", "content": "ATP balance and the effect of 2,4-dinitrophenol on fatty acid synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364986"}
{"pmid": "4364987", "title": "The sphingolipid composition of human renal carcinoma.", "content": "The sphingolipid composition of human renal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364987"}
{"pmid": "4364989", "title": "Isolation and characterization of an unsaponifiable lipid from Neurospora crassa.", "content": "Isolation and characterization of an unsaponifiable lipid from Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364989"}
{"pmid": "4364990", "title": "The nuclear lipids of bovine hypertrophic thyroid.", "content": "The nuclear lipids of bovine hypertrophic thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364990"}
{"pmid": "4364988", "title": "The lipid composition of the salt (rectal) gland of spiny dogfish.", "content": "The lipid composition of the salt (rectal) gland of spiny dogfish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364988"}
{"pmid": "4364991", "title": "Interaction of I-anilino-8-naphthalene sulphonate with human serum low-density lipoprotein.", "content": "Interaction of I-anilino-8-naphthalene sulphonate with human serum low-density lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364991"}
{"pmid": "4364992", "title": "Stimulation by angiotensin of myocardial prostaglandin synthesis.", "content": "Stimulation by angiotensin of myocardial prostaglandin synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364992"}
{"pmid": "4364993", "title": "The rate of polypeptide chain elongation in a cell-free system from Krebs II ascites cells.", "content": "The rate of polypeptide chain elongation in a cell-free system from Krebs II ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364993"}
{"pmid": "4364994", "title": "Modification of cytidine residues with a bisulfite-O-methylhydroxylamine mixture.", "content": "Modification of cytidine residues with a bisulfite-O-methylhydroxylamine mixture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364994"}
{"pmid": "4364996", "title": "Proceedings: active enhancement of mouse skin allografts: the effect of Bordetella pertussis and regional lymphadenectomy.", "content": "Proceedings: active enhancement of mouse skin allografts: the effect of Bordetella pertussis and regional lymphadenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364996"}
{"pmid": "4364995", "title": "Aetiology and prevention of wound infection in appendicetomy.", "content": "Aetiology and prevention of wound infection in appendicetomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364995"}
{"pmid": "4364997", "title": "Proceedings: The effects of mercury perchloride solution on collagen synthesis in rat colon anastomoses.", "content": "Proceedings: The effects of mercury perchloride solution on collagen synthesis in rat colon anastomoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364997"}
{"pmid": "4364999", "title": "Hydrolysis of bradykinin by angiotensin-converting enzyme.", "content": "Hydrolysis of bradykinin by angiotensin-converting enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364999"}
{"pmid": "4365001", "title": "Comparison between fractional turnover rate of endogenous plasma triglycerides and of intralipid (intravenous fat tolerance test) in man.", "content": "Comparison between fractional turnover rate of endogenous plasma triglycerides and of intralipid (intravenous fat tolerance test) in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365001"}
{"pmid": "4364998", "title": "Proceedings: Comparison of 99Tc-labelled polyphosphate, pyrophosphate and ethane hydroxydiphosphonate in patients with skeletal metastases.", "content": "Proceedings: Comparison of 99Tc-labelled polyphosphate, pyrophosphate and ethane hydroxydiphosphonate in patients with skeletal metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4364998"}
{"pmid": "4365002", "title": "Plasma cyclic AMP and total catecholamines during acute myocardial infarction in man.", "content": "Plasma cyclic AMP and total catecholamines during acute myocardial infarction in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365002"}
{"pmid": "4365003", "title": "Sex difference in the kinetics of triglyceride metabolism in normal and hypertriglyceridaemic human subjects.", "content": "Sex difference in the kinetics of triglyceride metabolism in normal and hypertriglyceridaemic human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365003"}
{"pmid": "4365004", "title": "Relationship between plasma concentrations of angiotensin I, angiotensin II and plasma renin activity during cardio-pulmonary bypass in man.", "content": "Relationship between plasma concentrations of angiotensin I, angiotensin II and plasma renin activity during cardio-pulmonary bypass in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365004"}
{"pmid": "4365005", "title": "Galactose metabolism in a patient with hereditary galactokinase deficiency.", "content": "Galactose metabolism in a patient with hereditary galactokinase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365005"}
{"pmid": "4365007", "title": "Presence of the same types of nonhistone chromosomal proteins in different tissues.", "content": "Presence of the same types of nonhistone chromosomal proteins in different tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365007"}
{"pmid": "4365006", "title": "Cycloheximide: a specific inhibitor of protein synthesis and intercellular ion transport in plant roots.", "content": "Cycloheximide: a specific inhibitor of protein synthesis and intercellular ion transport in plant roots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365006"}
{"pmid": "4365009", "title": "Muscarinic mediation of the biphasic temperature response to intrahypothalamic injections of carbachol in the cat.", "content": "Muscarinic mediation of the biphasic temperature response to intrahypothalamic injections of carbachol in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365009"}
{"pmid": "4365010", "title": "The cyclic AMP response to noradrenalin in young adult rat brain following post-natal injections of 6-hydroxydopamine.", "content": "The cyclic AMP response to noradrenalin in young adult rat brain following post-natal injections of 6-hydroxydopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365010"}
{"pmid": "4365008", "title": "Carbohydrate components of plasma membrane of transitional epithelium of urinary tract.", "content": "Carbohydrate components of plasma membrane of transitional epithelium of urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365008"}
{"pmid": "4365011", "title": "A neuralizing influence of dibutyryl cyclic AMP on competent chick ectoderm.", "content": "A neuralizing influence of dibutyryl cyclic AMP on competent chick ectoderm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365011"}
{"pmid": "4365012", "title": "Short term effects of dimethylnitrosamine and methylmethanesulphonate on hydrolases of the rat.", "content": "Short term effects of dimethylnitrosamine and methylmethanesulphonate on hydrolases of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365012"}
{"pmid": "4365016", "title": "Use of restriction endonucleases in analyzing the genome of simian virus 40.", "content": "Use of restriction endonucleases in analyzing the genome of simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365016"}
{"pmid": "4365021", "title": "The usefulness of the relaxation response in the therapy of headache.", "content": "The usefulness of the relaxation response in the therapy of headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365021"}
{"pmid": "4365024", "title": "The Epstein-Barr virus and its relationship to infectious mononucleosis in Air Force recruits.", "content": "The Epstein-Barr virus and its relationship to infectious mononucleosis in Air Force recruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365024"}
{"pmid": "4365023", "title": "Clinical evolution of Japanese encephalitis.", "content": "Clinical evolution of Japanese encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365023"}
{"pmid": "4365025", "title": "Venereal disease in Vietnam: clinical experience at a major military hospital.", "content": "Venereal disease in Vietnam: clinical experience at a major military hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365025"}
{"pmid": "4365030", "title": "Association of the Golgi complex with the plasma membrane of amphibian embryonic cells.", "content": "Association of the Golgi complex with the plasma membrane of amphibian embryonic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365030"}
{"pmid": "4365029", "title": "Glomus tympanicum tumours: early diagnosis by arteriography.", "content": "Glomus tympanicum tumours: early diagnosis by arteriography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365029"}
{"pmid": "4365028", "title": "Pediatric radiologic notes. Case no. 373. Mesenchymal hamartoma of the kidney in a neonate.", "content": "Pediatric radiologic notes. Case no. 373. Mesenchymal hamartoma of the kidney in a neonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365028"}
{"pmid": "4365045", "title": "Visna virus-induced fusion of continous simian kidney cells.", "content": "Visna virus-induced fusion of continous simian kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365045"}
{"pmid": "4365049", "title": "Properties of afferent nerve impulses originating from a neuroma.", "content": "Properties of afferent nerve impulses originating from a neuroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365049"}
{"pmid": "4365051", "title": "The blockade of angiotensin action by 8-leu-angiotensin on the guinea-pig aortic strip.", "content": "The blockade of angiotensin action by 8-leu-angiotensin on the guinea-pig aortic strip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365051"}
{"pmid": "4365052", "title": "Drinking elicited by polyethylene glycol and isoproterenol reduced by antiserum to angiotensin II.", "content": "Drinking elicited by polyethylene glycol and isoproterenol reduced by antiserum to angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365052"}
{"pmid": "4365053", "title": "Thrombocythaemia. Familial occurrence and transition into blastic crisis.", "content": "Thrombocythaemia. Familial occurrence and transition into blastic crisis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365053"}
{"pmid": "4365044", "title": "Release and metabolism of prostaglandins in lung tissue.", "content": "Release and metabolism of prostaglandins in lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365044"}
{"pmid": "4365054", "title": "A look at restraining practices and the use of psychotropic drugs.", "content": "A look at restraining practices and the use of psychotropic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365054"}
{"pmid": "4365063", "title": "Determination of the kinetic constants of fructose transport and phosphorylation in the perfused rat liver.", "content": "Determination of the kinetic constants of fructose transport and phosphorylation in the perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365063"}
{"pmid": "4365055", "title": "Which patient for which therapeutic group.", "content": "Which patient for which therapeutic group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365055"}
{"pmid": "4365064", "title": "The action of melittin on phosphatide multibilayers as studied by infrared dichroism and spin labeling. A model approach to lipid-protein interactions.", "content": "The action of melittin on phosphatide multibilayers as studied by infrared dichroism and spin labeling. A model approach to lipid-protein interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365064"}
{"pmid": "4365056", "title": "At what level does the psychiatric clinical specialist practice?", "content": "At what level does the psychiatric clinical specialist practice?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365056"}
{"pmid": "4365069", "title": "Ultrasonic patterns of tumors of the liver.", "content": "Ultrasonic patterns of tumors of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365069"}
{"pmid": "4365058", "title": "Sterilization and therapeutic abortion counseling for the mentally retarded.", "content": "Sterilization and therapeutic abortion counseling for the mentally retarded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365058"}
{"pmid": "4365059", "title": "Everybody gets angry sometime.", "content": "Everybody gets angry sometime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365059"}
{"pmid": "4365057", "title": "An expanded role for psychiatric nursing personnel: psychological evaluation and interpersonal care.", "content": "An expanded role for psychiatric nursing personnel: psychological evaluation and interpersonal care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365057"}
{"pmid": "4365070", "title": "Proceedings: Pharmacological aspect of enzymes related to cyclic AMP.", "content": "Proceedings: Pharmacological aspect of enzymes related to cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365070"}
{"pmid": "4365072", "title": "Proceedings: Studies on food poisoning due to Clostridium welchii.", "content": "Proceedings: Studies on food poisoning due to Clostridium welchii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365072"}
{"pmid": "4365061", "title": "Prospects for contraception.", "content": "Prospects for contraception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365061"}
{"pmid": "4365073", "title": "Proceedings: Inhibition of platelet cyclic AMP phosphodiesterase and platelet aggregation.", "content": "Proceedings: Inhibition of platelet cyclic AMP phosphodiesterase and platelet aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365073"}
{"pmid": "4365060", "title": "Nursing students and their learning experiences in geriatrics.", "content": "Nursing students and their learning experiences in geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365060"}
{"pmid": "4365074", "title": "Proceedings: Effect of antidiuretic hormone on cyclic adenosine 3',5'-monophosphate levels in rat kidney cells in culture.", "content": "Proceedings: Effect of antidiuretic hormone on cyclic adenosine 3',5'-monophosphate levels in rat kidney cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365074"}
{"pmid": "4365075", "title": "Proceedings: Fluorometric determination of cyclic AMP using dansyl chloride.", "content": "Proceedings: Fluorometric determination of cyclic AMP using dansyl chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365075"}
{"pmid": "4365071", "title": "Proceedings: Effects of prostaglandin E on the inhibitory responses of taenia coli produced by electrical stimulation.", "content": "Proceedings: Effects of prostaglandin E on the inhibitory responses of taenia coli produced by electrical stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365071"}
{"pmid": "4365062", "title": "Speaking out on: approaching a sensible position on public facilities and treatment resources for the mentally ill and mentally retarded?", "content": "Speaking out on: approaching a sensible position on public facilities and treatment resources for the mentally ill and mentally retarded?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365062"}
{"pmid": "4365076", "title": "Proceedings: Pharmacological analyses of action of DBc-AMP on the central nervous system of conscious dogs.", "content": "Proceedings: Pharmacological analyses of action of DBc-AMP on the central nervous system of conscious dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365076"}
{"pmid": "4365077", "title": "Proceedings: Excretion of cyclic AMP into duct saliva from the salivary gland.", "content": "Proceedings: Excretion of cyclic AMP into duct saliva from the salivary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365077"}
{"pmid": "4365078", "title": "Proceedings: Comparison of cardiovascular effects of dibutyryl cyclic AMP (DBcAMP) and cyclic AMP (cAMP).", "content": "Proceedings: Comparison of cardiovascular effects of dibutyryl cyclic AMP (DBcAMP) and cyclic AMP (cAMP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365078"}
{"pmid": "4365080", "title": "Proceedings: Effects of trazodone on monoamine metabolism in rat brain, as related to the paradoxical sleep suppressing effects.", "content": "Proceedings: Effects of trazodone on monoamine metabolism in rat brain, as related to the paradoxical sleep suppressing effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365080"}
{"pmid": "4365079", "title": "Proceedings: Regional differences in the sensitivity to several bioactive peptides in the venous system of dog.", "content": "Proceedings: Regional differences in the sensitivity to several bioactive peptides in the venous system of dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365079"}
{"pmid": "4365081", "title": "Proceedings: Physiological and pharmacological properties of bradikinin-sensitive dorsal horn neuron of the spinal cord.", "content": "Proceedings: Physiological and pharmacological properties of bradikinin-sensitive dorsal horn neuron of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365081"}
{"pmid": "4365082", "title": "Proceedings: Studies of the \"whorled body\" in the adrenocortical cell.", "content": "Proceedings: Studies of the \"whorled body\" in the adrenocortical cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365082"}
{"pmid": "4365084", "title": "Proceedings: Effects of antispasmodics on phosphodiesterase.", "content": "Proceedings: Effects of antispasmodics on phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365084"}
{"pmid": "4365083", "title": "Proceedings: Pharmacological studies on ganglionic transmission: effects of acetylcholine and catecholamines.", "content": "Proceedings: Pharmacological studies on ganglionic transmission: effects of acetylcholine and catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365083"}
{"pmid": "4365085", "title": "Proceedings: The effects of some drugs on the Ca++-uptake by microsomal fraction from guinea pig taenia coli.", "content": "Proceedings: The effects of some drugs on the Ca++-uptake by microsomal fraction from guinea pig taenia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365085"}
{"pmid": "4365087", "title": "Cellular and subcellular localization of 3H-oestradiol in the oviduct and uterus of the neonatal rat.", "content": "Cellular and subcellular localization of 3H-oestradiol in the oviduct and uterus of the neonatal rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365087"}
{"pmid": "4365088", "title": "Detergent dispersion of adenylate cyclase from partially purified rat liver plasma membranes.", "content": "Detergent dispersion of adenylate cyclase from partially purified rat liver plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365088"}
{"pmid": "4365086", "title": "Transcellular fluid formation and vascular permeability increase by angiotensins.", "content": "Transcellular fluid formation and vascular permeability increase by angiotensins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365086"}
{"pmid": "4365089", "title": "Cyclic 3',5'-nucleotide phosphodiesterase. Distribution and developmental changes of the enzyme and its protein activator in mammalian tissues and cells.", "content": "Cyclic 3',5'-nucleotide phosphodiesterase. Distribution and developmental changes of the enzyme and its protein activator in mammalian tissues and cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365089"}
{"pmid": "4365090", "title": "Effect of temperature upon inhibition by substrate of lactate dehydrogenase isoenzymes from a poikilotherm.", "content": "Effect of temperature upon inhibition by substrate of lactate dehydrogenase isoenzymes from a poikilotherm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365090"}
{"pmid": "4365091", "title": "Pilot experiments with EB virus in owl monkeys (Aotus trivirgatus). I Reticuloproliferative disease in an inoculated animal.", "content": "Pilot experiments with EB virus in owl monkeys (Aotus trivirgatus). I Reticuloproliferative disease in an inoculated animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365091"}
{"pmid": "4365092", "title": "Primary immunodeficiency diseases and cancer: the immunodeficiency-cancer registry.", "content": "Primary immunodeficiency diseases and cancer: the immunodeficiency-cancer registry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365092"}
{"pmid": "4365093", "title": "Sensitivity to EBV superinfection and IUdR inducibility of hybrid cells formed between a sensitive and a relatively resistant Burkitt lymphoma cell line.", "content": "Sensitivity to EBV superinfection and IUdR inducibility of hybrid cells formed between a sensitive and a relatively resistant Burkitt lymphoma cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365093"}
{"pmid": "4365094", "title": "Immunogenicity and immunosensitivity of SV40-transformed cells with different oncogenic potentials.", "content": "Immunogenicity and immunosensitivity of SV40-transformed cells with different oncogenic potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365094"}
{"pmid": "4365095", "title": "Analysis of minimal functions of simian virus 40. I. Oncogenic transformation of Syrian hamster kidney cells in vitro by photodynamically inactivated SV40.", "content": "Analysis of minimal functions of simian virus 40. I. Oncogenic transformation of Syrian hamster kidney cells in vitro by photodynamically inactivated SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365095"}
{"pmid": "4365096", "title": "Repair of radiation and chemical damage to DNA in human cells.", "content": "Repair of radiation and chemical damage to DNA in human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365096"}
{"pmid": "4365097", "title": "Triglyceride metabolism in skeletal muscle from normal and dystrophic mice.", "content": "Triglyceride metabolism in skeletal muscle from normal and dystrophic mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365097"}
{"pmid": "4365099", "title": "Current concepts of therapy in mushroom intoxication.", "content": "Current concepts of therapy in mushroom intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365099"}
{"pmid": "4365098", "title": "Quinones of Brevibacterium.", "content": "Quinones of Brevibacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365098"}
{"pmid": "4365100", "title": "Studies on the ribosomes of a thiopeptin-resistant mutant of Escherichia coli.", "content": "Studies on the ribosomes of a thiopeptin-resistant mutant of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365100"}
{"pmid": "4365102", "title": "Isolation of cold-sensitive mutants of simian virus 40.", "content": "Isolation of cold-sensitive mutants of simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365102"}
{"pmid": "4365101", "title": "Intestinal resistance in the experimental enteric infection of mice with a mouse adenovirus. 3. Suppressive effect of cyclophosphamide on the establishment and duration of the intestinal resistance.", "content": "Intestinal resistance in the experimental enteric infection of mice with a mouse adenovirus. 3. Suppressive effect of cyclophosphamide on the establishment and duration of the intestinal resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365101"}
{"pmid": "4365105", "title": "5-Keto-D-fructose. 8. Synthesis of 5-keto-D-fructose 1,6-bisphosphate and some of its properties.", "content": "5-Keto-D-fructose. 8. Synthesis of 5-keto-D-fructose 1,6-bisphosphate and some of its properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365105"}
{"pmid": "4365103", "title": "Cyclic nucleotide levels in incubations of guinea pig trachea.", "content": "Cyclic nucleotide levels in incubations of guinea pig trachea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365103"}
{"pmid": "4365106", "title": "Regulation of gluconeogenesis by alanine.", "content": "Regulation of gluconeogenesis by alanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365106"}
{"pmid": "4365107", "title": "Polysaccharides of the cellular slime mold. I. Extracellular polysaccharides in growth phase of Dictyostelium discoideum.", "content": "Polysaccharides of the cellular slime mold. I. Extracellular polysaccharides in growth phase of Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365107"}
{"pmid": "4365104", "title": "Modulation by cyclic AMP in vitro of liver plasma membrane (Na+--K+)-ATPase and protein kinases.", "content": "Modulation by cyclic AMP in vitro of liver plasma membrane (Na+--K+)-ATPase and protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365104"}
{"pmid": "4365108", "title": "Disulphide groups of gonadotropin receptors are essential for specific binding of human chorionic gonadotropin.", "content": "Disulphide groups of gonadotropin receptors are essential for specific binding of human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365108"}
{"pmid": "4365109", "title": "Ultrastructlral and histochemical observations of the external epithelium of echinoderm tube feet.", "content": "Ultrastructlral and histochemical observations of the external epithelium of echinoderm tube feet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365109"}
{"pmid": "4365110", "title": "Myodifferentiation in the carotid artery of the adult sheep: an ultrastructural study.", "content": "Myodifferentiation in the carotid artery of the adult sheep: an ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365110"}
{"pmid": "4365112", "title": "An electron microscopic study of the intraepidermal innervation of human glabrous skin.", "content": "An electron microscopic study of the intraepidermal innervation of human glabrous skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365112"}
{"pmid": "4365111", "title": "Effect of glucose loading on blood sugar and on the histology of the pancreatic islets in Clarias batrachus (Linn.).", "content": "Effect of glucose loading on blood sugar and on the histology of the pancreatic islets in Clarias batrachus (Linn.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365111"}
{"pmid": "4365113", "title": "Avian pox in a mourning dove.", "content": "Avian pox in a mourning dove.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365113"}
{"pmid": "4365114", "title": "Anti-herpesvirus action of isoprinosine.", "content": "Anti-herpesvirus action of isoprinosine. Anti-herpesvirus effects of Isoprinosine were found to be condition-dependent in vitro and in vivo. A herpes type 1 strain, grown in primary rabbit kidney cells, was not susceptible to Isoprinosine when cytopathic effect was evaluated, but was modestly inhibited when plaque-forming methocel overlay was used in the same cell line. However, the growth of a herpes type 2 strain was inhibited by Isoprinosine in this system when cytopathic effect was evaluated. Both viruses produced an encephalitis in hamsters after application by corneal abrasion. The encephalitis produced by a 1.5 mean lethal dose of herpesvirus was strikingly suppressed by large doses of Isoprinosine given ad libitum in the drinking water; this protection was not seen, however, at 15 mean lethal doses. Anti-herpes effects of Isoprinosine were suppressed by additional treatment with cortisone, both in tissue culture and in vivo. Isoprinosine, in the absence of virus infection, produced significant effects on the metabolism, structure, and function of brain ribosomes. In vivo, RNA components were labeled more rapidly and gave up their radioactivity more slowly after treatment with Isoprinosine. This enhanced cytoplasmic radioactivity was associated with a loss of incorporated radioactivity located in the nucleus and an increase in radioactivity located in a ribonucleo-protein fraction >4S and <18S. Ribosomes from treated brains gave physical evidence of being more compact (less orthochromic). Isoprinosine treatment increased the incorporation of [(14)C]phenylalanine into nascent protein in a cell-free system examining protein synthesis in brain polyribosomes. The addition of the exogenous messenger ribonucleic acid, polyuridylic acid, produced a significant age-dependent inhibition in the incorporation of [(14)C] phenylalanine. This inhibition was significantly greater when ribosomes were isolated from animals pretreated with Isoprinosine. These and other observations suggest that the Isoprinosine stimulation of host ribonucleic acid metabolism may be coupled to the production of ribosomes that do not effectively translate exogenous messenger ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365114"}
{"pmid": "4365116", "title": "Susceptibility of 1,500 isolates of Pseudomonas aeruginosa to gentamicin, carbenicillin, colistin, and polymyxin B.", "content": "Susceptibility of 1,500 isolates of Pseudomonas aeruginosa to gentamicin, carbenicillin, colistin, and polymyxin B. A series of 1,500 strains of Pseudomonas aeruginosa was collected from a variety of sources to provide a group of strains which would truly represent the species. All of them were pyocine typed, and a wide range of types was included among the isolates from each source. The gentamicin, carbenicillin, colistin, and polymyxin minimal inhibitory concentration of each strain was measured by the agar dilution method employing the Steers inocula replicator. Over 99% of strains were inhibited by 8 mug of gentamicin per ml, by 256 mug of carbenicillin per ml, and by 4 mug of colistin per ml. The small number of strains more resistant to each antibiotic comprised a variety of different pyocine types. Few strains were found to be susceptible to tetracycline, chloramphenicol, kanamycin, or streptomycin at the single concentration tested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365116"}
{"pmid": "4365115", "title": "Efficacy of trimethoprim and sulfamethoxazole in the prevention and treatment of Pneumocystis carinii pneumonitis.", "content": "Efficacy of trimethoprim and sulfamethoxazole in the prevention and treatment of Pneumocystis carinii pneumonitis. A combination of trimethoprim and sulfamethoxazole was effective in the prevention and treatment of Pneumocystis carinii pneumonitis in cortisonetreated rats. Although all of 15 untreated rats died with P. carinii pneumonitis, none of 15 given trimethoprim-sulfamethoxazole prophylactically acquired the infection. After P. carinii pneumonitis was established, 9 of 14 rats recovered after treatment with trimethoprim-sulfamethoxazole compared with only 2 of 14 treated with pentamidine isethionate. Rifampin and clindamycin, separately or in combination with pentamidine, were ineffective in the prevention and treatment of P. carinii infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365115"}
{"pmid": "4365117", "title": "Inhibition of Sindbis virus replication in HeLa cells by poliovirus.", "content": "Inhibition of Sindbis virus replication in HeLa cells by poliovirus. Concomitant infection of HeLa cells with poliovirus and Sindbis (SB) virus allowed replication of poliovirus only. The poliovirus-induced interference with the replication of SB virus was dependent partially on the multiplicity of SB virus used for infection. The observed interference was not sensitive to guanidine. Translation, but not replication of poliovirus, appears to be needed for the restriction of SB virus. Superinfection of SB virus-infected cultures with poliovirus was followed by inhibition of protein, but not by viral ribonucleic acid (RNA) synthesis. Polyribosomes present in SB virus-infected cells were disaggregated subsequent to superinfection. The nascent SB viral RNAs synthesized in cells subsequent to superinfection were not associated with the ribosomal structures. These results indicate that the block in protein synthesis, possibly at the level of initiation, may be the basis of the observed interference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365117"}
{"pmid": "4365120", "title": "Discharge from hospital: the problem of adjustment.", "content": "Discharge from hospital: the problem of adjustment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365120"}
{"pmid": "4365121", "title": "Culture of hepatitis B virus on a human cell line of hepatic origin. Preliminary results.", "content": "Culture of hepatitis B virus on a human cell line of hepatic origin. Preliminary results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365121"}
{"pmid": "4365118", "title": "Model studies in terpene biosynthesis.", "content": "Model studies in terpene biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365118"}
{"pmid": "4365123", "title": "Letter: Recognition of structural domains in globular proteins.", "content": "Letter: Recognition of structural domains in globular proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365123"}
{"pmid": "4365125", "title": "Unsuspected cytomegalic mononucleosis.", "content": "Unsuspected cytomegalic mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365125"}
{"pmid": "4365124", "title": "Specific immunodiagnosis of hepatocellular carcinoma by leucocyte adherence inhibition.", "content": "Specific immunodiagnosis of hepatocellular carcinoma by leucocyte adherence inhibition. The leucocyte adherence inhibition test provides a rapid, reliable, and specific technique for the immunodiagnosis of primary hepatocellular carcinoma (malignant hepatoma). The patient's blood leucocytes are tested in vitro for cell-mediated immunity against tumour-associated antigens and the serum is tested for blocking factor which interferes with the immunological reaction. Specific reactivity of both leucocytes and serum was consistently detected in patients with malignant hepatoma, and negative reactions were obtained in other liver diseases including secondary tumours of the liver. The test has provided positive evidence for the presence of hepatoma when more conventional methods gave doubtful or negative results. A positive result preceded the clinical appearance of tumour by up to three years in two patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365124"}
{"pmid": "4365126", "title": "Electrophysiological properties of the giant neurons of the leech subesophageal ganglion.", "content": "Electrophysiological properties of the giant neurons of the leech subesophageal ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365126"}
{"pmid": "4365122", "title": "Morphometric study of the ultrastructure of human alcoholic fatty liver.", "content": "Morphometric study of the ultrastructure of human alcoholic fatty liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365122"}
{"pmid": "4365127", "title": "Calcium and Purkinje cells in a perfused frog cerebellum.", "content": "Calcium and Purkinje cells in a perfused frog cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365127"}
{"pmid": "4365128", "title": "Recovery of neuronal activity and high-energy compound level after complete and prolonged brain ischemia.", "content": "Recovery of neuronal activity and high-energy compound level after complete and prolonged brain ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365128"}
{"pmid": "4365130", "title": "Ultrastructure of chondrosarcoma.", "content": "Ultrastructure of chondrosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365130"}
{"pmid": "4365129", "title": "Vascular lesions in the hand. Current management.", "content": "Vascular lesions in the hand. Current management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365129"}
{"pmid": "4365134", "title": "Photoconversions of bacteriochlorophylls and cytochromes in Chromatium chromatophores and cells under reducing conditions.", "content": "Photoconversions of bacteriochlorophylls and cytochromes in Chromatium chromatophores and cells under reducing conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365134"}
{"pmid": "4365135", "title": "The transsynaptic relationship between dopamine and serotonin in the caudate nucleus of cats.", "content": "The transsynaptic relationship between dopamine and serotonin in the caudate nucleus of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365135"}
{"pmid": "4365133", "title": "Inclusion of proteins of the cytoplasm of Zajdela hepatoma in the chromatin of rat liver cells.", "content": "Inclusion of proteins of the cytoplasm of Zajdela hepatoma in the chromatin of rat liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365133"}
{"pmid": "4365139", "title": "Fine structure of rat islet cell tumors induced by streptozotocin and nicotinamide.", "content": "Fine structure of rat islet cell tumors induced by streptozotocin and nicotinamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365139"}
{"pmid": "4365141", "title": "Aldosterone secretion in the enucleated rat adrenal during salt retention.", "content": "Aldosterone secretion in the enucleated rat adrenal during salt retention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365141"}
{"pmid": "4365142", "title": "Prostaglandin receptors in the human, monkey and hamster uterus.", "content": "Prostaglandin receptors in the human, monkey and hamster uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365142"}
{"pmid": "4365143", "title": "A comparison of cyclic nucleotide levels in plasma and cells of rat and human blood.", "content": "A comparison of cyclic nucleotide levels in plasma and cells of rat and human blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365143"}
{"pmid": "4365145", "title": "Proceedings: An explanation of the antiandrogenic properties of a non-steroidal compound, SCH 13521.", "content": "Proceedings: An explanation of the antiandrogenic properties of a non-steroidal compound, SCH 13521.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365145"}
{"pmid": "4365144", "title": "Prevention of illness from rhinovirus infection by a topical interferon inducer.", "content": "Prevention of illness from rhinovirus infection by a topical interferon inducer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365144"}
{"pmid": "4365146", "title": "Proceedings: Thyroid-stimulating hormone binding to human thyroid membranes and solubilized receptors.", "content": "Proceedings: Thyroid-stimulating hormone binding to human thyroid membranes and solubilized receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365146"}
{"pmid": "4365147", "title": "Proceedings: Corticosteroid feedback at the pituitary level.", "content": "Proceedings: Corticosteroid feedback at the pituitary level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365147"}
{"pmid": "4365149", "title": "Proceedings: Effect of human chorionic gonadotrophin on in-vivo levels of cyclic AMP in rabbit ovaries.", "content": "Proceedings: Effect of human chorionic gonadotrophin on in-vivo levels of cyclic AMP in rabbit ovaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365149"}
{"pmid": "4365148", "title": "Proceedings: Pituitary adrenocorticotrophic activity after adrenalectomy and adrenal enucleation in the rat.", "content": "Proceedings: Pituitary adrenocorticotrophic activity after adrenalectomy and adrenal enucleation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365148"}
{"pmid": "4365151", "title": "Hypothalamic control of gonadotrophin and prolactin secretion, implications for fertility control.", "content": "Hypothalamic control of gonadotrophin and prolactin secretion, implications for fertility control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365151"}
{"pmid": "4365150", "title": "The gonadotrophins and their releasing factors.", "content": "The gonadotrophins and their releasing factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365150"}
{"pmid": "4365153", "title": "Cholesteryl ester-rich inclusions from human aortic fatty streak and fibrous plaque lesions of atherosclerosis. I. Crystalline properties, size and internal structure.", "content": "Cholesteryl ester-rich inclusions from human aortic fatty streak and fibrous plaque lesions of atherosclerosis. I. Crystalline properties, size and internal structure. Cholesteryl esters, the major lipid in the lesions of human atherosclerosis, occurred in fatty streaks and fibrous plaques from 42 adults as spherical inclusions whose diameters averaged 1.99 +/- 0.48 and 2.16 +/- 0.62 mu, respectively, and which with polarizing light microscopy resolved into a mixture of various proportions of anisotropic and isotropic forms. Anisotropic forms had diameters of 1.9 +/- 0.4 mu, uniaxial-like symmetry with a formée cross image, a whitish gray interference color under cross polarizer and analyzer, second order blue and first order yellow interference colors with a tint plate, a birefringence of 0.0412 +/- 0.0054 and a refractive index of 1.559 +/- 0.0014. Their probable structural organization is primarily a lyotropic smectic mesophase (liquid crystal) of cholesteryl esters secondarily organized into multiple concentric lamellae. Isotropic forms had diameters of 2.3 +/- 0.6 mu and were optically inactive irrespective of their orientation. At 23 C, fatty streak inclusions from 21 subjects averaged significantly higher in the proportion of anisotropic forms, 85.5 +/- 9.3%, than did fibrous plaque inclusions from 21 subjects, which had 32.4 +/- 16.3% anisotropic forms (P < 0.01).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365153"}
{"pmid": "4365152", "title": "Hypoglycemia and insular hyperplasia: review of 148 cases.", "content": "Hypoglycemia and insular hyperplasia: review of 148 cases. On the bases of personal experience and the series of 148 cases from an international inquiry and a review of the literature, the relation between insular hyperplasia and hypoglycemia was examined. The fundamental points in this investigation included: age, diagnostic investigations, histological findings and postoperative results. The data on the patients with insular hyperplasia indicates that 83% were of adult age. Insular hyperplasia was the only abnormal factor determined to be present. Through treatment a high percentage of cases (71%) was cured. From a practical surgical point of view, differentiation between occult insulomas and insular hyperplasia is not critical. Consequently, good results can be achieved in botlh diseases by practicing a progressive blind resection guided by examination of the operated specimen and by intra-operative blood sugar levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365152"}
{"pmid": "4365154", "title": "Responses to exogenous adenosine 3',5'-monophosphate of cardiac output and blood flow in the renal, superior mesenteric and carotid arteries in anesthetized dogs.", "content": "Responses to exogenous adenosine 3',5'-monophosphate of cardiac output and blood flow in the renal, superior mesenteric and carotid arteries in anesthetized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365154"}
{"pmid": "4365155", "title": "Effect of corticosterone and cortisol on corticosteroidogenesis in isolated rat adrenal cells.", "content": "Effect of corticosterone and cortisol on corticosteroidogenesis in isolated rat adrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365155"}
{"pmid": "4365156", "title": "Studies on plasma membranes. XXI. Inhibition of liver plasma membrane enzymes by tumour-promoting phorbolester, mitotic inhibitors and cytochalasin B.", "content": "Studies on plasma membranes. XXI. Inhibition of liver plasma membrane enzymes by tumour-promoting phorbolester, mitotic inhibitors and cytochalasin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365156"}
{"pmid": "4365158", "title": "Proceedings: Acute toxicity of cyclic AMP in mice.", "content": "Proceedings: Acute toxicity of cyclic AMP in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365158"}
{"pmid": "4365157", "title": "Proceedings: Effect of calcium ion on renin release from renal cortex slices and isolated renin granules.", "content": "Proceedings: Effect of calcium ion on renin release from renal cortex slices and isolated renin granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365157"}
{"pmid": "4365159", "title": "Proceedings: Metabolism of N6,02'-dibutyryl-3', 5'-cyclic-AMP (DBcAMP).", "content": "Proceedings: Metabolism of N6,02'-dibutyryl-3', 5'-cyclic-AMP (DBcAMP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365159"}
{"pmid": "4365119", "title": "Nitrite in meat. Effect of various compounds on loss of nitrite.", "content": "Nitrite in meat. Effect of various compounds on loss of nitrite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365119"}
{"pmid": "4365161", "title": "Proceedings: Influence of morphine on ACTH secretion in the rat.", "content": "Proceedings: Influence of morphine on ACTH secretion in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365161"}
{"pmid": "4365160", "title": "Proceedings: Effects of cholinergic drugs on the synaptic transmission in isolated spinal cord-nerve-muscle preparation of the bullfrog.", "content": "Proceedings: Effects of cholinergic drugs on the synaptic transmission in isolated spinal cord-nerve-muscle preparation of the bullfrog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365160"}
{"pmid": "4365163", "title": "Response of plasma aldosterone to postural change, diuretica, angiotensin II, sodium restriction or loading and prostaglandin.", "content": "Response of plasma aldosterone to postural change, diuretica, angiotensin II, sodium restriction or loading and prostaglandin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365163"}
{"pmid": "4365162", "title": "Proceedings: Mechanism of relaxation of smooth muscle by 3-isopropyl-5,7-dipiperidinomethyltropolone hydrochloride (IDPT).", "content": "Proceedings: Mechanism of relaxation of smooth muscle by 3-isopropyl-5,7-dipiperidinomethyltropolone hydrochloride (IDPT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365162"}
{"pmid": "4365165", "title": "Coronavirus infections in military recruits. Three-year study with coronavirus strains OC43 and 229E.", "content": "Coronavirus infections in military recruits. Three-year study with coronavirus strains OC43 and 229E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365165"}
{"pmid": "4365167", "title": "The effects of sodium chromate on the proximal tubules of the rat kidney. Fine structural damage and lysozymuria.", "content": "The effects of sodium chromate on the proximal tubules of the rat kidney. Fine structural damage and lysozymuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365167"}
{"pmid": "4365166", "title": "Melanin: a normal component of human eosinophils.", "content": "Melanin: a normal component of human eosinophils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365166"}
{"pmid": "4365168", "title": "Effect of renin immunization on mercuric chloride and glycerol-induced renal failure.", "content": "Effect of renin immunization on mercuric chloride and glycerol-induced renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365168"}
{"pmid": "4365169", "title": "Letter: Down's syndrome, hypothyroidism, and diabetes mellitus.", "content": "Letter: Down's syndrome, hypothyroidism, and diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365169"}
{"pmid": "4365170", "title": "Temperature-sensitive pleiotropic revertants from a mutant in the arom gene cluster of Neurospora crassa.", "content": "Temperature-sensitive pleiotropic revertants from a mutant in the arom gene cluster of Neurospora crassa. Genetical and biochemical studies have been performed with revertants induced in a polyaromatic mutant (No. 58) in the arom gene cluster of Neurospora crassa. In addition to complete and partial revertants able to grow on minimal at both 25 degrees and 35 degrees , temperature-sensitive revertants capable of growth on minimal at 25 degrees but not at 35 degrees have been recovered. One of these revertants has been shown to lack biosynthetic dehydroquinase activity at both temperatures (utilizing the inducible catabolic isozyme for growth at 25 degrees ), to have dehydroshikimate reductase activity only at 25 degrees , and to form an arom aggregate having a molecular weight approximately one-half that of wild type. These results are interpreted as indicating that pleiotropic mutants in the arom gene cluster can result from missense mutations, as well as from nonsense mutations as indicated in previous studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365170"}
{"pmid": "4365171", "title": "Malignancy in pleomorphic adenoma. A clinical and microspectrophotometric study.", "content": "Malignancy in pleomorphic adenoma. A clinical and microspectrophotometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365171"}
{"pmid": "4365172", "title": "Diagnostic tests of facial nerve function.", "content": "Diagnostic tests of facial nerve function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365172"}
{"pmid": "4365173", "title": "Neoplastic involvement of the facial nerve.", "content": "Neoplastic involvement of the facial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365173"}
{"pmid": "4365178", "title": "Intracellular hydroxylation of non-helical protocollagen to form triple-helical procollagen and subsequent secretion of the molecule.", "content": "Intracellular hydroxylation of non-helical protocollagen to form triple-helical procollagen and subsequent secretion of the molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365178"}
{"pmid": "4365177", "title": "Reference values for cord blood lipid and lipoprotein concentrations.", "content": "Reference values for cord blood lipid and lipoprotein concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365177"}
{"pmid": "4365181", "title": "Mössbauer effect and electron spin resonance of the (iron)4-sulfur clusters of ferredoxin from Clostridium pasteurianum.", "content": "Mössbauer effect and electron spin resonance of the (iron)4-sulfur clusters of ferredoxin from Clostridium pasteurianum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365181"}
{"pmid": "4365179", "title": "Chromatographic analysis of aminoacyl tRNAs of poliovirus infected HEp-2 cells.", "content": "Chromatographic analysis of aminoacyl tRNAs of poliovirus infected HEp-2 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365179"}
{"pmid": "4365180", "title": "Studies on seed-oil triglycerides. Triglyceride biosynthesis and storage in whole seeds and oil bodies of Crambe abyssinica.", "content": "Studies on seed-oil triglycerides. Triglyceride biosynthesis and storage in whole seeds and oil bodies of Crambe abyssinica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365180"}
{"pmid": "4365182", "title": "Protein kinase activity in African swine fever virus.", "content": "Protein kinase activity in African swine fever virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365182"}
{"pmid": "4365175", "title": "Prostaglandins and inflammation.", "content": "Prostaglandins and inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365175"}
{"pmid": "4365183", "title": "Studies of glutamate dehydrogenase: chemical modification and quantitative determination of tryptophan residues.", "content": "Studies of glutamate dehydrogenase: chemical modification and quantitative determination of tryptophan residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365183"}
{"pmid": "4365176", "title": "Comparison of the PGE1 and catecholamines influence on the active transport of sodium.", "content": "Comparison of the PGE1 and catecholamines influence on the active transport of sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365176"}
{"pmid": "4365185", "title": "Foot-and-mouth disease virus: plaque reduction neutralization tests.", "content": "Foot-and-mouth disease virus: plaque reduction neutralization tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365185"}
{"pmid": "4365184", "title": "Hemadsorption cell-counting assay of interferon.", "content": "Hemadsorption cell-counting assay of interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365184"}
{"pmid": "4365186", "title": "ATPase and GTPase activities isolated from rat liver ribosomes.", "content": "ATPase and GTPase activities isolated from rat liver ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365186"}
{"pmid": "4365187", "title": "Neutralizing activity in the serum and oesophageal-pharyngeal fluid of cattle after exposure to foot-and-mouth disease virus and subsequent re-exposure.", "content": "Neutralizing activity in the serum and oesophageal-pharyngeal fluid of cattle after exposure to foot-and-mouth disease virus and subsequent re-exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365187"}
{"pmid": "4365189", "title": "The reactivation of C55-isoprenoid-alcohol-phosphokinase apoprotein by lipids. Evidence for lipid hydration in lipoprotein function.", "content": "The reactivation of C55-isoprenoid-alcohol-phosphokinase apoprotein by lipids. Evidence for lipid hydration in lipoprotein function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365189"}
{"pmid": "4365188", "title": "The intracellular location of pyruvate carboxylase in rat liver.", "content": "The intracellular location of pyruvate carboxylase in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365188"}
{"pmid": "4365190", "title": "The surface energetics of asbestos minerals.", "content": "The surface energetics of asbestos minerals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365190"}
{"pmid": "4365193", "title": "Adenosine 3',5'-cyclic phosphate, lipolysis and oxygen consumption in brown adipose tissue from newborn rabbits. Effect of cervical sympathectomy and of noradrenalin and theophylline in vitro, and the partial purification of an adenosine 3',5'-cyclic phosphate-dependent protein kinase.", "content": "Adenosine 3',5'-cyclic phosphate, lipolysis and oxygen consumption in brown adipose tissue from newborn rabbits. Effect of cervical sympathectomy and of noradrenalin and theophylline in vitro, and the partial purification of an adenosine 3',5'-cyclic phosphate-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365193"}
{"pmid": "4365196", "title": "Enhancement of the sensitivity of the immunodiffusion reaction in the detection of antibody against bovine adenoviruses.", "content": "Enhancement of the sensitivity of the immunodiffusion reaction in the detection of antibody against bovine adenoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365196"}
{"pmid": "4365197", "title": "Enhancement in excitability properties of mouse neuroblastoma cells cultured in the presence of dibutyryl cyclic AMP.", "content": "Enhancement in excitability properties of mouse neuroblastoma cells cultured in the presence of dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365197"}
{"pmid": "4365198", "title": "Aromatic sulfonic acids as viral inhibitors. Structure-activity study using rhino, adeno 3, herpes simplex, and influenza viruses.", "content": "Aromatic sulfonic acids as viral inhibitors. Structure-activity study using rhino, adeno 3, herpes simplex, and influenza viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365198"}
{"pmid": "4365199", "title": "Angiotensin II analogs. 5. (2-Glycine)angiotensin II and related analogs.", "content": "Angiotensin II analogs. 5. (2-Glycine)angiotensin II and related analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365199"}
{"pmid": "4365200", "title": "Septic arthritis of the hip joint secondary to umbilical artery catheterization associated with transient femoral and sciatic neuropathy.", "content": "Septic arthritis of the hip joint secondary to umbilical artery catheterization associated with transient femoral and sciatic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365200"}
{"pmid": "4365201", "title": "Potential antidiabetics. 9. Biological activity of some pyrazoles.", "content": "Potential antidiabetics. 9. Biological activity of some pyrazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365201"}
{"pmid": "4365204", "title": "Studies of malformation syndromes of man 33: the FG syndrome. An X-linked recessive syndrome of multiple congenital anomalies and mental retardation.", "content": "Studies of malformation syndromes of man 33: the FG syndrome. An X-linked recessive syndrome of multiple congenital anomalies and mental retardation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365204"}
{"pmid": "4365205", "title": "Protein kinase-catalyzed phosphorylation of muscle sarcolemma.", "content": "Protein kinase-catalyzed phosphorylation of muscle sarcolemma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365205"}
{"pmid": "4365207", "title": "Control of respiration by the mitochondrial phosphorylation state.", "content": "Control of respiration by the mitochondrial phosphorylation state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365207"}
{"pmid": "4365206", "title": "Differences in active center reactivity of trypsin homologs. Specific inactivation of thrombin by nitrophenyl p-amidinophenylmethanesulfonate.", "content": "Differences in active center reactivity of trypsin homologs. Specific inactivation of thrombin by nitrophenyl p-amidinophenylmethanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365206"}
{"pmid": "4365209", "title": "Hyperlipoproteinemia type V: biochemical observations in two cases.", "content": "Hyperlipoproteinemia type V: biochemical observations in two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365209"}
{"pmid": "4365208", "title": "Distribution of enzymes of glycogen metabolism and calcium uptake in skeletal muscle.", "content": "Distribution of enzymes of glycogen metabolism and calcium uptake in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365208"}
{"pmid": "4365210", "title": "Glucosylceramide in plasma of patients with Niemann-Pick disease.", "content": "Glucosylceramide in plasma of patients with Niemann-Pick disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365210"}
{"pmid": "4365211", "title": "The use of synthetic inhibitors to study the interaction of nicotinamide adenine dinucleotide with yeast alcohol dehydrogenase.", "content": "The use of synthetic inhibitors to study the interaction of nicotinamide adenine dinucleotide with yeast alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365211"}
{"pmid": "4365212", "title": "The renin-angiotensin system in the fetal lamb.", "content": "The renin-angiotensin system in the fetal lamb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365212"}
{"pmid": "4365213", "title": "Biochemical changes during progesterone-induced maturation in Xenopus laevis oocytes.", "content": "Biochemical changes during progesterone-induced maturation in Xenopus laevis oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365213"}
{"pmid": "4365214", "title": "Enzyme catalysis: conflicting requirements of substrate access and transition state affinity.", "content": "Enzyme catalysis: conflicting requirements of substrate access and transition state affinity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365214"}
{"pmid": "4365215", "title": "Receptor-binding assay of chemically modified insulins. Comparison with in vitro and in vivo bioassays.", "content": "Receptor-binding assay of chemically modified insulins. Comparison with in vitro and in vivo bioassays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365215"}
{"pmid": "4365217", "title": "Ocular manifestations of systemic disease.", "content": "Ocular manifestations of systemic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365217"}
{"pmid": "4365219", "title": "Plasma cyclic adenosine 3'5'-monophosphate (AMP) levels in acute myocardial infarction.", "content": "Plasma cyclic adenosine 3'5'-monophosphate (AMP) levels in acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365219"}
{"pmid": "4365220", "title": "Donovanosis: a morphologic study.", "content": "Donovanosis: a morphologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365220"}
{"pmid": "4365222", "title": "The maintenance of liver cells in vitro for virological and other studies.", "content": "The maintenance of liver cells in vitro for virological and other studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365222"}
{"pmid": "4365221", "title": "The adrenergic innervation of the gastrointestinal tract.", "content": "The adrenergic innervation of the gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365221"}
{"pmid": "4365227", "title": "Letter: Postmortem formation of giant endothelial vacuoles in Schlemm's canal.", "content": "Letter: Postmortem formation of giant endothelial vacuoles in Schlemm's canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365227"}
{"pmid": "4365226", "title": "Ultrastructural and histochemical studies of a newly recognized form of systemic mucopolysaccharidosis. (Maroteaux-Lamy syndrome, mild phenotype).", "content": "Ultrastructural and histochemical studies of a newly recognized form of systemic mucopolysaccharidosis. (Maroteaux-Lamy syndrome, mild phenotype).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365226"}
{"pmid": "4365229", "title": "Effect of N-methyl-N-nitrosourea on the protein-synthesizing system in mouse liver and hepatoma 22a cells.", "content": "Effect of N-methyl-N-nitrosourea on the protein-synthesizing system in mouse liver and hepatoma 22a cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365229"}
{"pmid": "4365228", "title": "Different degradation rates of alkylated RNA protein and lipids in normal and tumor cells.", "content": "Different degradation rates of alkylated RNA protein and lipids in normal and tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365228"}
{"pmid": "4365231", "title": "The catabolism of alpha1-fetoprotein and albumin in rats bearing Morris hepatoma 7777.", "content": "The catabolism of alpha1-fetoprotein and albumin in rats bearing Morris hepatoma 7777.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365231"}
{"pmid": "4365232", "title": "Diurnal distribution of motor activity and feeding during growth of tumors.", "content": "Diurnal distribution of motor activity and feeding during growth of tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365232"}
{"pmid": "4365230", "title": "Cytoplasmic glucocorticoid-binding proteins in glucocorticoid-unresponsive human and mouse leukemic cell lines.", "content": "Cytoplasmic glucocorticoid-binding proteins in glucocorticoid-unresponsive human and mouse leukemic cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365230"}
{"pmid": "4365233", "title": "A comparison of phenylalanyl-tRNA synthetase from rat liver and a minimal deviation hepatoma.", "content": "A comparison of phenylalanyl-tRNA synthetase from rat liver and a minimal deviation hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365233"}
{"pmid": "4365234", "title": "Evidence for bile acid synthesis by transplantable hepatomas.", "content": "Evidence for bile acid synthesis by transplantable hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365234"}
{"pmid": "4365235", "title": "Activity and hormone responsiveness of adenyl cyclase during induction of tumors in rat liver with 3'-methyl-4-dimethylaminoazobenzene.", "content": "Activity and hormone responsiveness of adenyl cyclase during induction of tumors in rat liver with 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365235"}
{"pmid": "4365236", "title": "Letter: Classification of mouse tumor viruses.", "content": "Letter: Classification of mouse tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365236"}
{"pmid": "4365237", "title": "A fast method of analysis of the 5' terminal nucleotides of deoxyribooligonucleotides.", "content": "A fast method of analysis of the 5' terminal nucleotides of deoxyribooligonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365237"}
{"pmid": "4365238", "title": "Isolation and characterisation of a mitochondrially synthesized precursor protein of cytochrome oxidase.", "content": "Isolation and characterisation of a mitochondrially synthesized precursor protein of cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365238"}
{"pmid": "4365240", "title": "Biological and immunological activity of fructose 1,6-bisphosphatase. Effect of structural changes on the quantitative displacement radioimmunoassay of fructose 1,6-bisphosphatase.", "content": "Biological and immunological activity of fructose 1,6-bisphosphatase. Effect of structural changes on the quantitative displacement radioimmunoassay of fructose 1,6-bisphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365240"}
{"pmid": "4365239", "title": "On the nature of argR mutations is Saccharomyces cerevisiae.", "content": "On the nature of argR mutations is Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365239"}
{"pmid": "4365242", "title": "Isotope effects and hydrogen transfer during simultaneous metabolism of ethanol and cyclohexanone in rats.", "content": "Isotope effects and hydrogen transfer during simultaneous metabolism of ethanol and cyclohexanone in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365242"}
{"pmid": "4365241", "title": "Purification and properties of N-acetylglucosamine kinase from human gastric mucosa.", "content": "Purification and properties of N-acetylglucosamine kinase from human gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365241"}
{"pmid": "4365244", "title": "Micturition symptoms in frontal tumours.", "content": "Micturition symptoms in frontal tumours. In a series of 50 consecutive tumours involving the frontal lobes, seven cases (14%) were found who exhibited the syndrome, first described by Andrew and Nathan in 1964, of frequency of micturition, urgency, and incontinence causing distress to the patient. This suggests that this syndrome may occur rather more commonly than those authors had indicated. In 100 consecutive intracranial tumours, no instances were found with non-frontal tumours, indicating that the syndrome may be of localizing value.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365244"}
{"pmid": "4365243", "title": "Benefit from adrenocorticotrophin in myasthenia gravis.", "content": "Benefit from adrenocorticotrophin in myasthenia gravis. Twenty-one of 29 patients suffering from myasthenia gravis derived benefit from a short intensive course of adrenocorticotrophin (ACTH). The mean duration of benefit was approximately six months. The best results were obtained in patients with a short history of myasthenia. Transient deterioration during the course of injections was encountered in some cases but necessitated assisted respiration only in patients with severe generalized weakness before treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365243"}
{"pmid": "4365245", "title": "Collagen films: effect of cross-linking on physical and biological properties.", "content": "Collagen films: effect of cross-linking on physical and biological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365245"}
{"pmid": "4365246", "title": "Epinephrine blockade of ribonuclease activity stimulation in lymphoid organs by cortisone and prostaglandin EI.", "content": "Epinephrine blockade of ribonuclease activity stimulation in lymphoid organs by cortisone and prostaglandin EI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365246"}
{"pmid": "4365248", "title": "Reaction of cytidine with ethylating agents.", "content": "Reaction of cytidine with ethylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365248"}
{"pmid": "4365249", "title": "Reaction of adenosine with ethylating agents.", "content": "Reaction of adenosine with ethylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365249"}
{"pmid": "4365252", "title": "Proton magnetic resonance studies of Desulfovibrio cytochromes c3.", "content": "Proton magnetic resonance studies of Desulfovibrio cytochromes c3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365252"}
{"pmid": "4365251", "title": "Characterization of the interaction between 17 beta-estradiol and its cytoplasmic receptor in the rat anterior pituitary gland.", "content": "Characterization of the interaction between 17 beta-estradiol and its cytoplasmic receptor in the rat anterior pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365251"}
{"pmid": "4365250", "title": "Regulation of adenylyl cyclase from isolated pancretic islets by prostaglandins and guanosine 5'-triphosphate.", "content": "Regulation of adenylyl cyclase from isolated pancretic islets by prostaglandins and guanosine 5'-triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365250"}
{"pmid": "4365254", "title": "The inhibition of avian myeloblastosis virus deoxyribonucleic acid polymerase by synthetic polynucleotides.", "content": "The inhibition of avian myeloblastosis virus deoxyribonucleic acid polymerase by synthetic polynucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365254"}
{"pmid": "4365257", "title": "Ribonucleic acid synthesis of vesicular stomatitis virus. VI. Correlation of defective particle RNA synthesis with standard RNA replication.", "content": "Ribonucleic acid synthesis of vesicular stomatitis virus. VI. Correlation of defective particle RNA synthesis with standard RNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365257"}
{"pmid": "4365259", "title": "Diminishing corticotrope capacity to release ACTH during sustained stimulation: the twenty-four hours after bilateral adrenalectomy in the rat.", "content": "Diminishing corticotrope capacity to release ACTH during sustained stimulation: the twenty-four hours after bilateral adrenalectomy in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365259"}
{"pmid": "4365261", "title": "Stimulation of uridine incorporation in isolated bone cells by parathyroid hormone and cyclic AMP.", "content": "Stimulation of uridine incorporation in isolated bone cells by parathyroid hormone and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365261"}
{"pmid": "4365258", "title": "Enhanced phosphatidylinositol labelling in rat parotid fragments exposed to alpha-adrenergic stimulation.", "content": "Enhanced phosphatidylinositol labelling in rat parotid fragments exposed to alpha-adrenergic stimulation. 1. Adrenergic agonists provoke a marked increase in labelling of phosphatidylinositol in fragments of rat parotid gland. 2. Adrenaline and phenylephrine (an adrenergic alpha-agonist) are effective stimulants, but isoprenaline (an adrenergic beta-agonist) is relatively ineffective. 3. The response evoked by phenylephrine or adrenaline is prevented by prior incubation of the tissue with phenoxybenzamine (an alpha-receptor blocking agent), but not by prior incubation with pindolol (a beta-receptor blocking agent). 4. Adrenergic stimulation of phosphatidylinositol metabolism in parotid gland is therefore mediated through alpha-receptors, in common with the adrenaline-induced K(+) efflux. It is not linked to enzyme secretion, which is triggered by stimulation of beta-receptors. 5. It is suggested that the stimulation of phospholipid metabolism that occurs in several other tissues in the presence of adrenaline or noradrenaline may also involve alpha-receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365258"}
{"pmid": "4365260", "title": "Metabolism of two adrenocorticotrophin analogues in the intestine of the rat.", "content": "Metabolism of two adrenocorticotrophin analogues in the intestine of the rat. 1. At 30min after oral administration unchanged Synacthen [corticotrophin-(1-24)-tetracosapeptide] was found in the stomach but could not be detected in the lumen of the small intestine of the rat. 2. Synacthen and 41795-Ba {[d-Ser(1), Lys(17), Lys(18)]corticotrophin-(1-18)-octadecapeptide amide} were rapidly metabolized in vitro by both intestinal juice and everted pieces of small intestine. Peptide products were not found either in the intestinal tissue or in the fluid bathing the serosal tissue. 3. Glucose but not O(2) was necessary for the breakdown of the two adrenocorticotrophin analogues by everted tissue. 4. When the products obtained after partial digestion were chromatographically separated and identified, a pattern of breakdown emerged. The N-terminus of Synacthen and the Phe(7)-Arg(8) bond in both analogues were particularly labile. The d-serine N-terminal residue of 41795-Ba conferred a marked protection to aminopeptidase action. 5. The relative susceptibilities of peptide bonds would have been difficult to predict on the basis of existing knowledge of the properties of enzymes of the small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365260"}
{"pmid": "4365263", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-1974. Recurrent abdominal pain and fever post cholecystectomy.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-1974. Recurrent abdominal pain and fever post cholecystectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365263"}
{"pmid": "4365247", "title": "Molecular aspects for the metabolic regulation of the nicotinamide adenine dinucleotide-dependent D(-)-lactate dehydrogenase from Leuconostoc.", "content": "Molecular aspects for the metabolic regulation of the nicotinamide adenine dinucleotide-dependent D(-)-lactate dehydrogenase from Leuconostoc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365247"}
{"pmid": "4365266", "title": "Proceedings: Investigation of steroid-receptor interaction in pregnant sheep myometrium.", "content": "Proceedings: Investigation of steroid-receptor interaction in pregnant sheep myometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365266"}
{"pmid": "4365265", "title": "Proceedings: Characterization of adrenocortical cell receptors for adrenocorticotrophin.", "content": "Proceedings: Characterization of adrenocortical cell receptors for adrenocorticotrophin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365265"}
{"pmid": "4365267", "title": "Effects of silica and asbestos on cells in culture.", "content": "Effects of silica and asbestos on cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365267"}
{"pmid": "4365269", "title": "Proceedings: Functional affinities of the non-zoned adrenocortical tissue of the skink Tiliqua rugosa with the zone glomerulosa of the rat adrenal.", "content": "Proceedings: Functional affinities of the non-zoned adrenocortical tissue of the skink Tiliqua rugosa with the zone glomerulosa of the rat adrenal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365269"}
{"pmid": "4365273", "title": "Proceedings: Adrenal function, oestrogen and the control of parturition in the guinea-pig.", "content": "Proceedings: Adrenal function, oestrogen and the control of parturition in the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365273"}
{"pmid": "4365272", "title": "Proceedings: Thyroid function in the foetal calf.", "content": "Proceedings: Thyroid function in the foetal calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365272"}
{"pmid": "4365274", "title": "Proceedings: A correlated biochemical and morphological study of the development of adrenocorticotrophin-sensitive adenylate cyclase activity in foetal rabbit adrenals.", "content": "Proceedings: A correlated biochemical and morphological study of the development of adrenocorticotrophin-sensitive adenylate cyclase activity in foetal rabbit adrenals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365274"}
{"pmid": "4365275", "title": "Proceedings: Stimulation of melanocyte-stimulating hormone release in vitro by cyclic AMP.", "content": "Proceedings: Stimulation of melanocyte-stimulating hormone release in vitro by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365275"}
{"pmid": "4365270", "title": "Proceedings: Functional and morphological changes occuring in rat adrenal zona glomerulosa cells in monolayer culture.", "content": "Proceedings: Functional and morphological changes occuring in rat adrenal zona glomerulosa cells in monolayer culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365270"}
{"pmid": "4365276", "title": "The effect of antibiotics on the growth and longevity of human diploid fibroblasts in vitro.", "content": "The effect of antibiotics on the growth and longevity of human diploid fibroblasts in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365276"}
{"pmid": "4365271", "title": "Inhibition of growth and respiration by visible and near-visible light.", "content": "Inhibition of growth and respiration by visible and near-visible light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365271"}
{"pmid": "4365277", "title": "An electron microscopic study of a single-cycle infection of Madin-Darby bovine kidney cells by infectious bovine rhinotracheitis virus.", "content": "An electron microscopic study of a single-cycle infection of Madin-Darby bovine kidney cells by infectious bovine rhinotracheitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365277"}
{"pmid": "4365278", "title": "The radiology corner. Insulin-producing tumors of the pancreas.", "content": "The radiology corner. Insulin-producing tumors of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365278"}
{"pmid": "4365279", "title": "Isolation and properties of cytochrome a deficient mutants of Bacillus subtilis.", "content": "Isolation and properties of cytochrome a deficient mutants of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365279"}
{"pmid": "4365280", "title": "Effect of prolonged chlorpromazine administration on the sleep of chronic schizophrenics.", "content": "Effect of prolonged chlorpromazine administration on the sleep of chronic schizophrenics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365280"}
{"pmid": "4365282", "title": "The formation of methylated bases in DNA by dimethylnitrosamine and its relation to differences in the formation of tumours in the livers of GR and C3HF mice.", "content": "The formation of methylated bases in DNA by dimethylnitrosamine and its relation to differences in the formation of tumours in the livers of GR and C3HF mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365282"}
{"pmid": "4365264", "title": "Chemistry of animal venoms.", "content": "Chemistry of animal venoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365264"}
{"pmid": "4365284", "title": "EPR studies on the mechanism of biotransformation of tricyclic neuroleptics and antidepressants.", "content": "EPR studies on the mechanism of biotransformation of tricyclic neuroleptics and antidepressants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365284"}
{"pmid": "4365286", "title": "Inhibition by phenothiazines of adenylate cyclase in adrenal and brain tissue.", "content": "Inhibition by phenothiazines of adenylate cyclase in adrenal and brain tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365286"}
{"pmid": "4365285", "title": "Hydroxylation of 7-hydroxychlorpromazine by mushroom tyrosinase.", "content": "Hydroxylation of 7-hydroxychlorpromazine by mushroom tyrosinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365285"}
{"pmid": "4365289", "title": "Replication of temperature sensitive mutant of infectious bovine rhinotracheitis virus in the tissues of inoculated calves.", "content": "Replication of temperature sensitive mutant of infectious bovine rhinotracheitis virus in the tissues of inoculated calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365289"}
{"pmid": "4365290", "title": "Bovine abortion associated with Cytomegalovirus infection.", "content": "Bovine abortion associated with Cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365290"}
{"pmid": "4365288", "title": "Applied anatomical aspects of pain.", "content": "Applied anatomical aspects of pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365288"}
{"pmid": "4365287", "title": "Effects of phenothiazines and phenothiazine metabolites on adenyl cyclase and the cyclic AMP response in the rat brain.", "content": "Effects of phenothiazines and phenothiazine metabolites on adenyl cyclase and the cyclic AMP response in the rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365287"}
{"pmid": "4365292", "title": "Influence of heart rate on the reduction of sympathetic outflow produced by L-dopa.", "content": "Influence of heart rate on the reduction of sympathetic outflow produced by L-dopa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365292"}
{"pmid": "4365294", "title": "Pituitary 45 Ca ion uptake and release of ACTH, GH, and TSH: effect of verapamil.", "content": "Pituitary 45 Ca ion uptake and release of ACTH, GH, and TSH: effect of verapamil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365294"}
{"pmid": "4365293", "title": "Beta-adrenergic effects on rat myometrium: role of cyclic AMP.", "content": "Beta-adrenergic effects on rat myometrium: role of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365293"}
{"pmid": "4365295", "title": "Effect of PGE1, indomethacin, and polyphloretin phosphate on toad bladder response to ADH.", "content": "Effect of PGE1, indomethacin, and polyphloretin phosphate on toad bladder response to ADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365295"}
{"pmid": "4365296", "title": "Acute intermittent porphyria, hypercholesterolaemia, and renal impairment.", "content": "Acute intermittent porphyria, hypercholesterolaemia, and renal impairment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365296"}
{"pmid": "4365297", "title": "Sensitization to ragweed pollen in Bordetella pertussis-infected or vaccine-injected mice.", "content": "Sensitization to ragweed pollen in Bordetella pertussis-infected or vaccine-injected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365297"}
{"pmid": "4365298", "title": "Effects of glucocorticosteroids on the urinary excretion of cyclic AMP and electrolytes by asthmatic children.", "content": "Effects of glucocorticosteroids on the urinary excretion of cyclic AMP and electrolytes by asthmatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365298"}
{"pmid": "4365299", "title": "An electron microscopic study of the giant cells in proliferative myositis.", "content": "An electron microscopic study of the giant cells in proliferative myositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365299"}
{"pmid": "4365301", "title": "Primary liver carcinoma.", "content": "Primary liver carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365301"}
{"pmid": "4365303", "title": "The bioavailability of iron sources and their utilization in food enrichment.", "content": "The bioavailability of iron sources and their utilization in food enrichment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365303"}
{"pmid": "4365306", "title": "Letter: Burkitt's lymphoma.", "content": "Letter: Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365306"}
{"pmid": "4365305", "title": "Familial hypobetalipoproteinemia: report of a case with psychomotor retardation.", "content": "Familial hypobetalipoproteinemia: report of a case with psychomotor retardation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365305"}
{"pmid": "4365308", "title": "Viral probes of aging in the human diploid cell strain WI-38.", "content": "Viral probes of aging in the human diploid cell strain WI-38.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365308"}
{"pmid": "4365307", "title": "Effects of cholecalciferol on bone formation and serum calcium, phosphate and magnesium in chicks.", "content": "Effects of cholecalciferol on bone formation and serum calcium, phosphate and magnesium in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365307"}
{"pmid": "4365309", "title": "Effect of angiotensin converting enzyme inhibition on renal autoregulation.", "content": "Effect of angiotensin converting enzyme inhibition on renal autoregulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365309"}
{"pmid": "4365300", "title": "Proceedings: 231. Role of Ca++ and Mg++ in neuromuscular transmission and excitation of the radula protractor.", "content": "Proceedings: 231. Role of Ca++ and Mg++ in neuromuscular transmission and excitation of the radula protractor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365300"}
{"pmid": "4365310", "title": "125I-glucagon binding and adenylate cyclase activation in the fetal rat heart.", "content": "125I-glucagon binding and adenylate cyclase activation in the fetal rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365310"}
{"pmid": "4365311", "title": "An improved immunoperoxidase technique for identifying SV40 V and T antigens by light microscopy.", "content": "An improved immunoperoxidase technique for identifying SV40 V and T antigens by light microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365311"}
{"pmid": "4365304", "title": "Proceedings: 350. Aerobic dependence of synaptic transmission at the outer plexiform layer in the fish retina.", "content": "Proceedings: 350. Aerobic dependence of synaptic transmission at the outer plexiform layer in the fish retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365304"}
{"pmid": "4365313", "title": "Effect of hypophysectomy and pretreatment on uptake and retention of estradiol by the ovary.", "content": "Effect of hypophysectomy and pretreatment on uptake and retention of estradiol by the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365313"}
{"pmid": "4365312", "title": "Effect of nonsteroidal antiinflammatory drugs on plasma protein-thyroxine interaction.", "content": "Effect of nonsteroidal antiinflammatory drugs on plasma protein-thyroxine interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365312"}
{"pmid": "4365314", "title": "Depression of frog isolated spinal cord by morphine and antagonism by tetracosactin.", "content": "Depression of frog isolated spinal cord by morphine and antagonism by tetracosactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365314"}
{"pmid": "4365316", "title": "Malignant fibrous histiocytoma of spermatic cord.", "content": "Malignant fibrous histiocytoma of spermatic cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365316"}
{"pmid": "4365315", "title": "Enhancement of interferon antiviral action in L-cells by cyclic nucleotides.", "content": "Enhancement of interferon antiviral action in L-cells by cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365315"}
{"pmid": "4365317", "title": "Effect of adenosine 3',5'-cyclic monophosphate on the morphogenesis of fruit bodies of Schizophyllum commune.", "content": "Effect of adenosine 3',5'-cyclic monophosphate on the morphogenesis of fruit bodies of Schizophyllum commune.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365317"}
{"pmid": "4365318", "title": "Cyclophosphamide in disseminated bronchial carcinoma.", "content": "Cyclophosphamide in disseminated bronchial carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365318"}
{"pmid": "4365319", "title": "Relationships between antimicrobial activities and chemical structures of reduced products of viomycin.", "content": "Relationships between antimicrobial activities and chemical structures of reduced products of viomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365319"}
{"pmid": "4365302", "title": "Proceedings: 261. On the projection from the parietal association cortex to the cerebellum.", "content": "Proceedings: 261. On the projection from the parietal association cortex to the cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365302"}
{"pmid": "4365322", "title": "Self-annealing of Sendai virus RNA.", "content": "Self-annealing of Sendai virus RNA. Both complementary strands are found in 50S Sendai virion RNA. 50S Sendai virion RNA has been shown to consist of unequal amounts of a single population of plus and minus strands by annealing studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365322"}
{"pmid": "4365321", "title": "Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins.", "content": "Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. Based on evidence that 50% of herpes simplex 1 DNA is transcribed in HEp-2 cells in the absence of protein synthesis we examined the order and rates of synthesis of viral polypeptides in infected cells after reversal of cycloheximide- or puromycin-mediated inhibition of protein synthesis. These experiments showed that viral polypeptides formed three sequentially synthesized, coordinately regulated groups designated alpha, beta, and gamma. Specifically: (i) The alpha group, containing one minor structural and several nonstructural polypeptides, was synthesized at highest rates from 3 to 4 h postinfection in untreated cells and at diminishing rates thereafter. The beta group, also containing minor structural and nonstructural polypeptides, was synthesized at highest rates from 5 to 7 h and at decreasing rates thereafter. The gamma group containing major structural polypeptides was synthesized at increasing rates until at least 12 h postinfection. (ii) The synthesis of alpha polypeptides did not require prior infected cell protein synthesis. In contrast, the synthesis of beta polypeptides required both prior alpha polypeptide synthesis as well as new RNA synthesis, since the addition of actinomycin D immediately after removal of cycloheximide precluded beta polypeptide synthesis. The function supplied by the alpha polypeptides was stable since interruption of protein synthesis after alpha polypeptide synthesis began and before beta polypeptides were made did not prevent the immediate synthesis of beta polypeptides once the drug was withdrawn. The requirement of gamma polypeptide synthesis for prior synthesis of beta polypeptides seemed to be similar to that of beta polypeptides for prior synthesis of the alpha group. (iii) The rates of synthesis of alpha polypeptides were highest immediately after removal of cycloheximide and declined thereafter concomitant with the initiation of beta polypeptide synthesis; this decline in alpha polypeptide synthesis was less rapid in the presence of actinomycin D which prevented the appearance of beta and gamma polypeptides. The decrease in rates of synthesis of beta polypeptides normally occurring after 7 h postinfection was also less rapid in the presence of actinomycin D than in its absence, whereas ongoing synthesis of gamma polypeptides at this time was rapidly reduced by actinomycin D. (iv) Inhibitors of DNA synthesis (cytosine arabinoside or hydroxyurea) did not prevent the synthesis of alpha, beta, or gamma polypeptides, but did reduce the amounts of gamma polypeptides made.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365321"}
{"pmid": "4365323", "title": "Detection of baboon type C viral sequences in various primate tissues by molecular hybridization.", "content": "Detection of baboon type C viral sequences in various primate tissues by molecular hybridization. Nucleic acid sequences homologous to a single-stranded [(3)H]DNA transcript prepared from a baboon type C virus replicating in dog thymus cells can be readily detected in the cellular DNA of several Old World monkeys (baboon, patas, African green, and two species of macaques-rhesus and stumptail). These results demonstrate that primates other than the baboon also contain endogenous type C viral genes. With the hybridization conditions employed (S(1) nuclease, 65 C), no homologous sequences were detected in DNA from human or New World monkey tissues. Of various nonprimate tissues examined, only domestic cat cellular DNA was partially homologous to the baboon virus [(3)H]DNA transcript. In reciprocal experiments, [(3)H]DNA transcripts of RNAs from endogenous cat viruses (RD-114/CCC group) show a significant partial homology with cellular DNA from Old World primates (baboon, patas, and rhesus monkey). The partial homology between type-C-related information in the DNA of domestic cats and various Old World monkeys suggests the possibility of horizontal transmission between the progenitors of these animals at some point in evolution. No nucleic acid sequences homologous to [(3)H]DNA transcripts prepared from type C viruses isolated from tumor tissue of a woolly monkey and a gibbon ape could be detected in any primate tissue DNA examined; however, a partial nucleic acid homology was found between woolly monkey and gibbon ape type C viral [(3)H]DNA and normal mouse cellular DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365323"}
{"pmid": "4365324", "title": "Specific fragmentation of DNA of adenovirus serotypes 3, 5, 7, and 12, and adeno-simian virus 40 hybrid virus Ad2+ND1 by restriction endonuclease R.EcoRI.", "content": "Specific fragmentation of DNA of adenovirus serotypes 3, 5, 7, and 12, and adeno-simian virus 40 hybrid virus Ad2+ND1 by restriction endonuclease R.EcoRI. The products of complete digestion of duplex DNA of each of seven human adenoviruses with restriction endonuclease R. EcoRI ranged from two fragments for adenovirus 7 DNA (Ad7) to six fragments for Ad12 and Ad2 DNA. Viral serotypes from the same subgroups appeared to have related cleavage sites; Ad3 DNA and Ad7 (cl E46-LL) DNA were each cleaved into three fragments, and Ad7 (cl 19) DNA lacked one of the cleavage sites present in Ad3 and Ad7 (cl E46-LL) DNA. One of the cleavage sites in Ad2 DNA was deleted in the DNA' of adeno-SV40 hybrid virus Ad2(+)ND1, and three of the cleavage sites in Ad2 DNA were missing in Ad5 DNA. Thus, Ad2(+)ND1 DNA was cleaved into five and Ad5 DNA into three fragments. Each fragment represented a unique segment of viral DNA since each fragment was obtained in equimolar amounts and since the sum of the molecular weights of the fragments equaled the molecular weight of the homologous intact adenovirus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365324"}
{"pmid": "4365325", "title": "Isolation and partial characterization of bacteriophage T5 mutants deficient in the ability to induce deoxynucleoside monophosphate kinase.", "content": "Isolation and partial characterization of bacteriophage T5 mutants deficient in the ability to induce deoxynucleoside monophosphate kinase. Two mutants of bacteriophage T5 deficient in the ability to induce wild-type levels of deoxynucleoside monophosphate kinase were isolated and partially characterized. Both mutations were demonstrated to be in a structural gene for the kinase. One of the mutants, designated dnk 10, induces no detectable levels of dCMP, dGMP, or dTMP kinase activity. Because the mutant can successfully infect nonpermissive cells, phage-induced deoxynucleoside monophosphate kinase appears to be an unessential function for phage production. DNA synthesis in dnk 10-infected cells, however, is reduced to 30% of that observed in wild-type-infected cells; phage production is reduced by a comparable amount. The dnk mutation has been mapped and located on the \"C\" region of the T5 genetic map, 6.3 map units from the C1 locus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365325"}
{"pmid": "4365326", "title": "Mechanism of Sindbis virus-induced intrinsic interference with vesicular stomatitis virus replication.", "content": "Mechanism of Sindbis virus-induced intrinsic interference with vesicular stomatitis virus replication. Heterologous viral interference is induced by Sindbis virus against vesicular stomatitis virus (VSV) in a manner analogous to intrinsic interference with Newcastle disease virus replication. Interference in both systems (i) depends upon early expression of the inducing virus genome, (ii) shows similar kinetics of induction, (iii) does not involve interferon action, and (iv) appears to be manifest as an all-or-none effect. VSV can be added to the list of viruses blocked by intrinsic interference. Sindbis virus-induced intrinsic interference with VSV replication is not mediated through homotypic interference by defective interfering particles; rather, T-particle and B-particle synthesis is inhibited. Significantly, intrinsic interference has no effect on primary transcription directed by the virion-associated transcriptase in VSV-challenged cells. However, Sindbis virus appears to induce interference with the VSV-RNA synthesized subsequent to primary transcription, namely, that which is dependent on protein synthesis. Thus, the target of intrinsic interference appears to be a reaction subsequent to primary transcription but prior to the appearance of protein synthesis-dependent VSV RNA, secondary transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365326"}
{"pmid": "4365327", "title": "Reconstitution of infectivity and transcriptase activity of homologous and heterologous viruses: vesicular stomatitis (Indiana serotype), Chandipura, vesicular stomatitis (New Jersey serotype), and Cocal viruses.", "content": "Reconstitution of infectivity and transcriptase activity of homologous and heterologous viruses: vesicular stomatitis (Indiana serotype), Chandipura, vesicular stomatitis (New Jersey serotype), and Cocal viruses. RNA TRANSCRIPTASE ACTIVITIES HAVE BEEN RECONSTITUTED FROM FRACTIONATED COMPONENTS OF FOUR RHABDOVIRUSES: vesicular stomatitis virus (VSV) (Indiana serotype), Cocal, VSV (New Jersey), and Chandipura viruses. Heterologous reconstitution of transcription has been observed between template and enzyme fractions of VSV Indiana and Cocal viruses but not to any significant extent between components of the other two viruses with VSV Indiana template or enzyme. Homologous reconstitution of infectivity has been obtained for each virus from their respective parts as well as heterologous reconstitution between Cocal and VSV Indiana components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365327"}
{"pmid": "4365328", "title": "Phosphate acceptor amino acid residues in structural proteins of rhabdoviruses.", "content": "Phosphate acceptor amino acid residues in structural proteins of rhabdoviruses. Partial acid hydrolysates of the [(32)P]phosphate- or [(3)H]serine-labeled proteins of purified vesicular stomatitis, rabies, Lagos bat, Mokola, or spring viremia of carp virions and of purified intracellular nucleocapsids of these viruses have been analyzed by paper electrophoresis for the presence of phosphorylated amino acids. Both phosphoserine and phosphothreonine, with the former predominant, were present in virion and nucleocapsid preparations that contained phosphoproteins. An exception was the fish rhabdovirus, which contained only phosphoserine. When vesicular stomatitis or rabies virus proteins were phosphorylated in a cell-free system by the virion-associated protein kinase and analyzed for the presence of phosphorylated amino acid residues, phosphoserine was again found to be more abundant than phosphothreonine. After in vitro protein phosphorylation, another phospho-compound, possibly a third phosphoamino acid, was detected in the partial acid hydrolysates of these viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365328"}
{"pmid": "4365329", "title": "Structure and molecular length of the large subunits of RD-114 viral RNA.", "content": "Structure and molecular length of the large subunits of RD-114 viral RNA. By electron microscopy, the large subunits of RD-114 RNA have a molecular weight of 5.0 x 10(6); they all have a characteristic secondary structure feature close to the middle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365329"}
{"pmid": "4365330", "title": "Host cell regulation of induction of Epstein-Barr virus.", "content": "Host cell regulation of induction of Epstein-Barr virus. When Epstein-Barr virus (EBV) negative cells (Raji) were treated with iododeoxyuridine, only the early antigen (EA) component was induced. There was no significant increase in EBV DNA and no virus particles were observed. Somatic-cell hybrids were prepared from the fusion of Raji and D98 cells (D98/Raji). When these cells were treated with iododeoxyuridine, early antigen EBV DNA, and virus particles were synthesized. These data suggest cellular control over the expression of the EBV genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365330"}
{"pmid": "4365331", "title": "Simple, quantitative assay for both xenotropic murine leukemia and ecotropic feline leukemia viruses.", "content": "Simple, quantitative assay for both xenotropic murine leukemia and ecotropic feline leukemia viruses. A cat cell line carrying the genome of a murine sarcoma virus developed discrete foci in linear response to infection with feline leukemia virus or xenotropic murine C-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365331"}
{"pmid": "4365335", "title": "Isospora callimico n sp, (Coccidia: Eimeriidae) from Goeldi's marmoset (Callimico goeldii).", "content": "Isospora callimico n sp, (Coccidia: Eimeriidae) from Goeldi's marmoset (Callimico goeldii).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365335"}
{"pmid": "4365334", "title": "The effects of noise level and elevated ambient temperatures upon selected reproductive traits in female Swiss-Webster mice.", "content": "The effects of noise level and elevated ambient temperatures upon selected reproductive traits in female Swiss-Webster mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365334"}
{"pmid": "4365336", "title": "Effect of open and closed formula rations on the performance of three strains of laboratory mice.", "content": "Effect of open and closed formula rations on the performance of three strains of laboratory mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365336"}
{"pmid": "4365337", "title": "A semisynthetic diet for long-term maintenance of hamsters to study effects of dietary vitamin A.", "content": "A semisynthetic diet for long-term maintenance of hamsters to study effects of dietary vitamin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365337"}
{"pmid": "4365338", "title": "The erythrocyte life span in the American opossum (Didelphis marsupialis Virginiana).", "content": "The erythrocyte life span in the American opossum (Didelphis marsupialis Virginiana).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365338"}
{"pmid": "4365339", "title": "Use of ventriculo-cisternal perfusion in conscious sheep.", "content": "Use of ventriculo-cisternal perfusion in conscious sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365339"}
{"pmid": "4365340", "title": "The parasitic ecology of the rodent mite Myobia musculi. I. Grooming factors.", "content": "The parasitic ecology of the rodent mite Myobia musculi. I. Grooming factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365340"}
{"pmid": "4365341", "title": "A feeder for controlling food consumption in treatment-control pairs of mice.", "content": "A feeder for controlling food consumption in treatment-control pairs of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365341"}
{"pmid": "4365342", "title": "Cranial hyperostosis of squirrel monkeys (Saimiri sciureus).", "content": "Cranial hyperostosis of squirrel monkeys (Saimiri sciureus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365342"}
{"pmid": "4365343", "title": "Malignant melanoma in a black gerbil (Meriones unguiculatus).", "content": "Malignant melanoma in a black gerbil (Meriones unguiculatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365343"}
{"pmid": "4365346", "title": "Letter: Time of fertility as reflected by urinary protein levels.", "content": "Letter: Time of fertility as reflected by urinary protein levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365346"}
{"pmid": "4365345", "title": "Letter: Duodenal ulcer formation in the rat.", "content": "Letter: Duodenal ulcer formation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365345"}
{"pmid": "4365344", "title": "Blood chemistry of the rat kangaroo, Potorous tridactylus.", "content": "Blood chemistry of the rat kangaroo, Potorous tridactylus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365344"}
{"pmid": "4365347", "title": "The biogenesis of mitochondria during proliferation and muturation of the intestinal epithelium of the rat. Effects of oxytetracycline.", "content": "The biogenesis of mitochondria during proliferation and muturation of the intestinal epithelium of the rat. Effects of oxytetracycline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365347"}
{"pmid": "4365352", "title": "A new and fast method of preparation of CEA.", "content": "A new and fast method of preparation of CEA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365352"}
{"pmid": "4365353", "title": "In vitro study on the effects of bradykinin potentiating factor and angiotensin II analogue on degradation and conversion of angiotensin I and II in plasma.", "content": "In vitro study on the effects of bradykinin potentiating factor and angiotensin II analogue on degradation and conversion of angiotensin I and II in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365353"}
{"pmid": "4365358", "title": "Selected topics in immunology: infectious mononucleosis and Australia antigen.", "content": "Selected topics in immunology: infectious mononucleosis and Australia antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365358"}
{"pmid": "4365360", "title": "Are there differences in contact inhibition of movement between normal and malignant cells.", "content": "Are there differences in contact inhibition of movement between normal and malignant cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365360"}
{"pmid": "4365359", "title": "Injection of foreign substances into single cells by cell fusion.", "content": "Injection of foreign substances into single cells by cell fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365359"}
{"pmid": "4365362", "title": "Neurotrophic control of colchicine effects on muscle?", "content": "Neurotrophic control of colchicine effects on muscle?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365362"}
{"pmid": "4365361", "title": "Evidence that mitogenic lectins induce changes in lymphocyte membrane fluidity.", "content": "Evidence that mitogenic lectins induce changes in lymphocyte membrane fluidity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365361"}
{"pmid": "4365364", "title": "Syndrome of accelerated skeletal maturation in infancy, peculiar facies, and multiple congenital anomalies.", "content": "Syndrome of accelerated skeletal maturation in infancy, peculiar facies, and multiple congenital anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365364"}
{"pmid": "4365363", "title": "The neuropharmacology of aggression: a critical review.", "content": "The neuropharmacology of aggression: a critical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365363"}
{"pmid": "4365365", "title": "Temperature-dependent expression of transformation by cold-sensitive mutant of murine sarcoma virus.", "content": "Temperature-dependent expression of transformation by cold-sensitive mutant of murine sarcoma virus. Morphological transformation of normal rat kidney cells by a murine sarcoma virus was found to be cold-sensitive. Cells transformed by the virus expressed their transformed phenotype at the permissive temperature (39 degrees ) but not at the nonpermissive temperature (33 degrees ), as judged by the criteria of morphological changes and colony-forming ability on monolayers of normal rat kidney cells. Cold-sensitive expression of transformation was specific for focus-derived normal rat kidney cells transformed by the virus, readily reversible, and not lost during serial propagation of the cells. The genome of the murine sarcoma virus can be rescued by superinfection with Moloney leukemia virus at the permissive or nonpermissive temperature, and the rescued virus exhibited the same cold-sensitive properties as the original transforming virus. These results suggest that maintenance of the transformed state is continuously dependent on a cold-sensitive viral function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365365"}
{"pmid": "4365366", "title": "Identification of the chloramphenicol-binding protein in Escherichia coli ribosomes by partial reconstitution.", "content": "Identification of the chloramphenicol-binding protein in Escherichia coli ribosomes by partial reconstitution. 50S-derived cores were prepared by treatment of 50S subunits with 0.4 M Licl (0.4c core) and 0.8 M Licl (0.8c core), respectively. 0.4c cores bind chloramphenicol whereas 0.8c cores do not. The split proteins obtained during the transitions 0.4c --> 0.8c were separated by DEAE-cellulose chromatography and Sephadex G-100 gel filtration. Reconstitution experiments with the fractionated proteins demonstrated that protein L16 is involved in chloramphenicol binding. In contrast to chloramphenicol, the CACCA-(N-acetyl-leucyl) fragment is bound by the 0.8c core, i.e., this core contains the intact p-site moiety of the peptidyltransferase center. Puromycin can inhibit chloramphenicol binding completely. In the concentration range tested (up to 20 mM) the trinucleotide CCA inhibits chloramphenicol binding as effectively as puromycin, whereas an aminoacid mixture shows no inhibition. It is concluded that chloramphenicol acts exclusively on the a-site part of the peptidyltransferase center interfering with the binding of the last two or three nucleotides (3' end) of aminoacyl-tRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365366"}
{"pmid": "4365367", "title": "The synthesis and enzymatic polymerization of nucleotides containing mercury: potential tools for nucleic acid sequencing and structural analysis.", "content": "The synthesis and enzymatic polymerization of nucleotides containing mercury: potential tools for nucleic acid sequencing and structural analysis. A simple acetoxymercuration reaction for introducing covalently bound mercury atoms into nucleotides is described. The 5-mercuriacetate derivatives of UTP, CTP, dUTP, and dCTP, as well as the 7-mercuriacetate derivative of 7-deazaATP, have been prepared by this procedure and tested as substrates for nucleic acid polymerases. These nucleotides, in the absence of added mercaptan, are not polymerized and in most instances are potent enzyme inhibitors. However, conversion of these mercuriacetates to mercurithio compounds in situ by the addition of one of various mercaptans, yields nucleoside triphosphates that are excellent substrates for all polymerases tested: Escherichia coli and T7 RNA polymerases, DNA polymerase I of E. coli, DNA polymerase of avian myeloblastosis virus, and calf-thymus terminal deoxynucleotidyl transferase. By varying the mercaptan used to promote syntheses it is possible to access certain structural limitations in the enzyme's nucleoside triphosphate binding site. These mercurinucleotides appear to have a diversity of potential applications: (1) as heavy-atom reagents for crystallographic and microscopic studies; (2) as affinity probes for enzymes sensitive to sulfhydryl modification; (3) as steric probes of substrate-binding sites on enzymes; and (4) as reagents for forming covalent protein-polynucleotide complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365367"}
{"pmid": "4365368", "title": "Biological activity of 1alpha-hydroxycholecalciferol, a synthetic analog of the hormonal form of vitamin D3.", "content": "Biological activity of 1alpha-hydroxycholecalciferol, a synthetic analog of the hormonal form of vitamin D3. 1,25-Dihydroxycholecalciferol, the apparent active hormonal form of cholecalciferol (vitamin D(2)), is formed from cholecalciferol by specific and sequential hydroxylations of the sterol at carbons 25 and 1. Recently, 1alpha-hydroxycholecalciferol was synthesized and we report on its biological activity in rachitic chicks. 1alpha-Hydroxycholecalciferol is identical in potency to 1,25-dihydroxycholecalciferol in stimulation of intestinal calcium absorption; either sterol elicits a near maximal effect at a dose of 0.3-0.6 nmol. The time-course of action of 1alpha-hydroxycholecalciferol also parallels that of the active metabolite 1,25-dihydroxycholecalciferol with a maximal increase in calcium transport occurring 5-10 hr after administration of sterol to vitamin D-deficient chicks. 6.5 nmol of 1alpha-hydroxycholecalciferol causes a doubling in calcium absorption in only 2-3 hr, which is the most rapid physiologic response yet detected for a vitamin D-sterol. 1alpha-Hydroxycholecalciferol is active also in enhancing bone calcium resorption and, like 1,25-dihydroxycholecalciferol, is at least 10 times as active as cholecalciferol in mobilizing bone calcium and raising plasma calcium concentration. It is concluded that 1alpha-hydroxycholecalciferol represents a synthetic analog of 1,25-dihydroxycholecalciferol that can be used both to study the mechanism of action of this hormone and as a therapeutic agent in the treatment of patients with certain metabolic bone diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365368"}
{"pmid": "4365370", "title": "Induction of the stellate configuration in cultured iris epithelial cells by adenosine and compounds related to adenosine 3':5'-cyclic monophosphate.", "content": "Induction of the stellate configuration in cultured iris epithelial cells by adenosine and compounds related to adenosine 3':5'-cyclic monophosphate. Adenosine, dibutyryl cyclic AMP, monobutyryl cyclic AMP, cyclic AMP, and 5'-AMP have a remarkable morphogenetic effect on cultured iris epithelial cells obtained from adult newt. They alter the broad undulating membrane of the cell into branching strands of cytoplasm, a configuration that has been named \"stellate.\" Theophylline, a phosphodiesterase inhibitor also induces the stellate configuration. This transient morphological alteration is detectable by 30 min and becomes maximal 80 min after treatment. In the continued presence of the effective compounds the altered cells return to their normal shape, although the recovery period is variable. The morphological alteration of iris epithelial cells in vitro observed in the present experiment is reminiscent of that which occurs during the dedifferentiation phase in lens regeneration in vivo. These observations suggest that induction of the stellate configuration is relevant to the mechanism of dedifferentiation of newt iris epithelial cells during Wolffian lens regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365370"}
{"pmid": "4365369", "title": "Lateral phase separations in membrane lipids and the mechanism of sugar transport in Escherichia coli.", "content": "Lateral phase separations in membrane lipids and the mechanism of sugar transport in Escherichia coli. Changes in slope of Arrhenius plots for transport can, in some instances, be detected at two different temperatures for cells that have a relatively simple fatty-acid composition in the membrane lipids. These characteristic temperatures correlate with the characteristic temperatures that define changes of state in membrane phospholipids as revealed by the paramagnetic resonance of the spin label TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl). The higher of these characteristic temperatures is that at which the formation of solid patches of membrane lipids is first detected. The lower is the end point of the course of lateral phase separations, at which all the membrane lipids are in a solid phase. For cells enriched for elaidic acid, the rate of transport increase by as much as 2-fold as the temperature is decreased by less than 1 degrees , at the higher characteristic temperature. At this characteristic temperature, lateral phase separations begin in the membrane phospholipids. This is also the temperature where one predicts a striking increase in the lateral compressibility of the membrane lipids. These data are thus interpreted to indicate that a component of the transport system vertically penetrates one or both monolayer faces of the membrane during transport, or that some other event involving the lateral compression of the phospholipids is important for transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365369"}
{"pmid": "4365371", "title": "Enumeration of activated thymus-derived lymphocytes by the virus plaque assay.", "content": "Enumeration of activated thymus-derived lymphocytes by the virus plaque assay. Lymphocytes activated by antigens or mitogens acquire the capacity to replicate viruses, and the number of activated lymphocytes can be estimated by the virus plaque assay. Concanavalin A and pokeweed mitogen produced 33-fold and 17-fold increases in virus plaqueforming cells (V-PFC), respectively, above background, while lipopolysaccharide produced only a 2- to 3-fold increase. T (thymus-derived lymphocyte)-depleted lymphocyte populations, derived from anti-theta-treated or nude (arthymic) mouse spleens, failed to produce V-PFC after culture with concanavalin A or pokeweed mitogen. The present studies thus demonstrate that the virus plaque assay measures activated T-lymphocytes.A dissociation between the V-PFC response and cell proliferation was previously observed in antigen-stimulated cells cultured in the presence of mitotic inhibitors. In the present studies, while stimulation of CBA (H2(k)) lymphocytes by DBA/2 (H2(d)) cells produced high levels of thymidine incorporation, lymphocyte target-cell cytotoxicity, and V-PFC, stimulation of BALB/c (H2(d)) lymphocytes against DBA/2 (H2(d)) cells resulted in even higher levels of thymidine incorporation with a virtual absence of cytotoxic lymphocytes or V-PFC. These results indicate that proliferation is not a sufficient condition for permitting lymphocytes either to exert cytotoxicity on target cells or to replicate viruses, and suggest that there may be a correlation between the development of V-PFC and cytotoxic lymphocytes. They are consistent with the view that there are at least two functional subpopulations of T-lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365371"}
{"pmid": "4365372", "title": "In vitro transcription of simian virus 40 sequences in SV3T3 chromatin.", "content": "In vitro transcription of simian virus 40 sequences in SV3T3 chromatin. The template properties of chromatin were studied in a system in which transcription of unique genes could be examined. Chromation and DNA were isolated from SV3T3 cells, a line of simian virus 40 (SV40)-transformed mouse cells, and used as templates for Escherichia coli RNA polymerase. The SV40 sequences in the RNA transcribed in vitro and in RNA isolated from the transformed cells were analyzed by hybridization to radioactive RNA transcribed from SV40 DNA. The results indicate that the same sequences of the SV40 \"-\" strand (DNA strand which serves as a template for early RNA) are transcribed in vitro from chromatin as are found in transformed cells. In contrast, when the DNA isolated from SV3T3 chromatin by removal of proteins is used as a template, the entire SV40 \"-\" strand is transcribed. It is concluded that the specific template restriction observed with chromatin is due to the presence of proteins associated with the DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365372"}
{"pmid": "4365373", "title": "Adhesion of cultured fibroblasts to insoluble analogues of cell-surface carbohydrates.", "content": "Adhesion of cultured fibroblasts to insoluble analogues of cell-surface carbohydrates. Animal cells are coated with complex carbohydrates. Insoluble analogues of these substances were prepared by coupling monosaccharides to Sephadex beads (crosslinked dextran), and the interactions between these derivatives and three established cell lines were studied. A virally transformed fibroblast, simian virus 40-transformed 3T3 cells, adhered to the beads derivatized with D-galactose, but did not adhere to the corresponding beads derivatized with D-glucose or N-acetyl-D-glucosamine. Cells that adhered to the galactose-beads appeared to initiate a nucleation process in that they became more adhesive towards the cells in suspension, leading to the formation of large aggregates containing both cells and galactose-beads. The results suggest that specific carbohydrates are involved in the processes of cell recognition or cell adhesion, or both.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365373"}
{"pmid": "4365374", "title": "Antiviral effect of interferon covalently bound to sepharose.", "content": "Antiviral effect of interferon covalently bound to sepharose. Interferon, covalently bound to Sepharose 4B activated by cyanogen bromide, induces the antiviral state in sensitive cells. The antiviral effect is neutralized by antiserum specific to interferon and is recovered thereafter when the antibody is detached from the interferon by treatment at low pH. Binding interferon to Sepharose increases the stability of the molecule. It is likely that the interferon molecule acts on the cell receptor without being detached from the beads. However, the data do not exclude the possibility of a small loss of interferon, or fragments of it, after contact with the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365374"}
{"pmid": "4365375", "title": "A cell-contact model for cellular position determination in development.", "content": "A cell-contact model for cellular position determination in development. The fate of a cell in a developing organism is a function of its position within the organism. The molecular mechanism that cells use to determine their position and to convert positional information into a form that can be used to regulate the expression of genes is not understood. This paper presents a model in which contacts between complementary molecules on plasma membranes of adjacent cells regulate the concentration of a morphogenetic substance and transmit positional information. This model is described by four equations that, when solved with realistic parameters, demonstrated that this mechanism will produce discrete populations of cells within a few hours from an initially undifferentiated array of cells. The model suggests an explanation for several phenomena that have been observed and suggests experiments to test it and to clearly differentiate it from other models for position determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365375"}
{"pmid": "4365376", "title": "NAD(P) glycohydrolase deficiency in human erythrocytes and alteration of cytosol NADH-methemoglobin diaphorase by membrane NAD-glycohydrolase activity.", "content": "NAD(P) glycohydrolase deficiency in human erythrocytes and alteration of cytosol NADH-methemoglobin diaphorase by membrane NAD-glycohydrolase activity. Erythrocytic NADH methemoglobin diaphorase acquires NADH-dichlorophenolindophenol diaphorase activity when enzyme-associated NAD is removed. This transformation is reversible and can be mediated by membrane NAD glycohydrolase (EC 3.2.2.5) in hemolysates as well as in intact cells exposed to hydrogen peroxide. It is abolished either in NADH methemoglobin diaphorase deficiency or in NAD(P) glycohydrolase (EC 3.2.2.6) deficiency which is common in Afro-American but not in European-American adults. Activities of erythrocytic NADP glycohydrolase and NAD glycohydrolase appear to depend on a single membrane enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365376"}
{"pmid": "4365377", "title": "Supersensitivity and subsensitivity of the beta-adrenergic receptor in pineal gland regulated by catecholamine transmitter.", "content": "Supersensitivity and subsensitivity of the beta-adrenergic receptor in pineal gland regulated by catecholamine transmitter. Depletion of neural norepinephrine by reserpine treatment or by denervation resulted in a greater induction of serotonin N-acetyltransferase (EC 2.3.1.5) and a higher elevation of cyclic AMP in postsynaptic pineal cell to small amount of isoproterenol. This increase in responsiveness occurs rapidly within 24 hr after treatment with reserpine. Repeated administration of isoproterenol to the denervated or reserpine-treated rats not only suppressed the superinduction, but also caused a decreased response to isoproterenol in cultured pineal cells. Cultured pineal cells from denervated or reserpine-treated rats were about 10 times more responsive to small amounts of isoproterenol. The response of cultured pineal cells of rats which were repeatedly injected with isoproterenol was markedly reduced after exposure to submaximal amounts of catecholamines. The maximal increase in N-acetyltransferase was the same in denervated, reserpine-treated, isoproterenol-treated, and untreated pineal cells. Exposure of rats to continuous lighting (a procedure that reduces sympathetic nerve activity) resulted in a superinduction of pineal N-acetyltransferase by isoproterenol. These observations indicate that the responsiveness of the postsynaptic beta-adrenergic receptor is conditioned by prior exposure to its agonist, norepinephrine. Decreased norepinephrine results in supersensitivity, and repeated exposure to large amounts of catecholamines causes subsensitivity (tolerance).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365377"}
{"pmid": "4365378", "title": "The synthesis in vitro of RNA polymerase subunits of Escherichia coli.", "content": "The synthesis in vitro of RNA polymerase subunits of Escherichia coli. DNA from transducing bacteriophage that carry the structural gene for the beta subunit of RNA polymerase has been used to direct protein synthesis in a cell-free transcription-translation system. A polypeptide species has been detected which appears to be beta-subunit material made in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365378"}
{"pmid": "4365379", "title": "Structure of liver alcohol dehydrogenase at 2.9-angstrom resolution.", "content": "Structure of liver alcohol dehydrogenase at 2.9-angstrom resolution. The conformation of the polypeptide chain in horse liver alcohol dehydrogenase (EC 1.1.1.1), as well as the binding sites for some inhibitor molecules, have been determined from x-ray crystallographic data to a resolution of 2.9 A. Each subunit of the dimeric molecule is organized into two parts unequal in size and separated by a wide and deep active-site cleft. The adenosine moiety of the coenzyme is bound within the smaller region. Interactions between these coenzyme-binding substructures define the subunit contact area of the molecule. The \"catalytic\" zinc atoms are bound at the bottom of the clefts about 20 A from the surface of the molecule. The coenzyme binding region has a main-chain conformation very similar to a corresponding region in lactate and malate dehydrogenase. It is suggested that this substructure is a general one for binding of nucleotides and, in particular, the coenzyme NAD(+).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365379"}
{"pmid": "4365380", "title": "Mechanism of action of nerve growth factor and cyclic AMP on neurite outgrowth in embryonic chick sensory ganglia: demonstration of independent pathways of stimulation.", "content": "Mechanism of action of nerve growth factor and cyclic AMP on neurite outgrowth in embryonic chick sensory ganglia: demonstration of independent pathways of stimulation. The suggested role of adenosine 3':5'-cyclic monophosphate as the \"second messenger\" in the neurite outgrowth from chick embryonic sensory ganglia mediated by nerve growth factor was examined. Although N(6),O(2)-dibutyryl adenosine 3':5'-cyclic monophosphate induces fiber outgrowth at concentrations of 1-5 mM, this response is morphologically distinct from that produced by nerve growth factor, is pH dependent, is mimicked by sodium butyrate, and does not occur in sympathetic ganglia. In addition, nerve growth factor does not alter the amounts of intracellular cyclic AMP during incubations up to 24 hr and does not stimulate adenylate cyclase in broken-cell preparations. Addition of theophylline, an inhibitor of phosphodiesterase, causes increases in intracellular levels of cyclic AMP but does not affect fiber outgrowth. These observations indicate that the nerve growth factor response is not mediated through cyclic AMp and that stimulation of sensory ganglia by exogenous cyclic AMP derivatives is probably of limited physiological significance. These findings are also compatible with the developing hypothesis, based on structural similarities, that nerve growth factor and insulin exert their effects on their respective responsive tissues by related mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365380"}
{"pmid": "4365381", "title": "Growth inhibition and morphological changes caused by lipophilic acids in mammalian cells.", "content": "Growth inhibition and morphological changes caused by lipophilic acids in mammalian cells. Human (HeLa, Chang liver, L-132, and Intestine 407) and other mammalian (XC, SV3T3, and chick-embryo) cells in tissue culture are at least as sensitive to inhibition by lipophilic acids and nitrite as bacteria. Some of these compounds are the most frequently used antimicrobial food additives. Short-chain fatty acids (up to hexanoate) and parabens induce, at partially inhibitory concentrations, a jagged cell shape in continuous epithelial-like cell lines, such as HeLa, Chang liver, L-132, and Intestine 407. This morphological effect is not mediated or enhanced by butyryl cyclic AMP, which specifically affects fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365381"}
{"pmid": "4365383", "title": "Regulation of 25-hydroxycholecalciferol metabolism by inorganic phosphate.", "content": "Regulation of 25-hydroxycholecalciferol metabolism by inorganic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365383"}
{"pmid": "4365382", "title": "Presynaptic inhibition at inhibitory nerve terminals.  A new synapse in the crayfish stretch receptor.", "content": "Presynaptic inhibition at inhibitory nerve terminals.  A new synapse in the crayfish stretch receptor. Previous physiological evidence has shown that the receptor neuron of the slowly adapting stretch receptor organ of crayfish receives synapses from three inhibitory axons, while the receptor muscle is innervated by both excitatory and inhibitory axons. Fine structural studies have indicated that after certain preparative procedures synaptic vesicles in the inhibitory terminals on dendrites of the receptor neuron appear small and elongate, while those in the excitatory terminals on the receptor muscle are round and larger. This study describes a new synapse between two inhibitory nerve endings on the receptor neuron. One axon, containing small elongate vesicles, forms a presynaptic chemical contact with another morphologically similar axon that, itself, presumably releases inhibitory transmitter onto the receptor neuron. A second type of presynaptic axo-axonic synapse, analogous to one previously described in another crustacean muscle, was also found between presumed inhibitory and excitatory nerve terminals on the receptor muscle. Thus, the stretch receptor has a relatively complex organization with a morphological basis for two types of presynaptic inhibition: one on excitatory terminals and the other on inhibitory terminals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365382"}
{"pmid": "4365384", "title": "Malignancy of the uterine corpus following irradiation therapy for squamous cell carcinoma of the cervix.", "content": "Malignancy of the uterine corpus following irradiation therapy for squamous cell carcinoma of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365384"}
{"pmid": "4365385", "title": "Studies on a specific glucocorticoid-hormone receptor in the developing chick retina.", "content": "Studies on a specific glucocorticoid-hormone receptor in the developing chick retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365385"}
{"pmid": "4365386", "title": "Karyometry in the estimation of nuclear population in pulmonary carcinomas.", "content": "Karyometry in the estimation of nuclear population in pulmonary carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365386"}
{"pmid": "4365387", "title": "Ultrastructure of human mesotheliomas.", "content": "Ultrastructure of human mesotheliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365387"}
{"pmid": "4365388", "title": "Titrations of various mouse mammary tumor viruses in different mouse strains.", "content": "Titrations of various mouse mammary tumor viruses in different mouse strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365388"}
{"pmid": "4365389", "title": "Mechanism of resistance to mammary tumor development in C57BL and I strains of mice. II. Inherent differences between the two strains.", "content": "Mechanism of resistance to mammary tumor development in C57BL and I strains of mice. II. Inherent differences between the two strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365389"}
{"pmid": "4365390", "title": "C-type particles in baboon (Papio cynocephalus) preimplantation embryos.", "content": "C-type particles in baboon (Papio cynocephalus) preimplantation embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365390"}
{"pmid": "4365391", "title": "Inhibitory effect of 2-br-alpha-ergocryptine-methane-sulfonate on renal carcinogenesis in the male hamster.", "content": "Inhibitory effect of 2-br-alpha-ergocryptine-methane-sulfonate on renal carcinogenesis in the male hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365391"}
{"pmid": "4365393", "title": "Letter: Doxapram hydrochloride.", "content": "Letter: Doxapram hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365393"}
{"pmid": "4365392", "title": "Proceedings: Experimental observations on intestinal healing in malignant disease.", "content": "Proceedings: Experimental observations on intestinal healing in malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365392"}
{"pmid": "4365395", "title": "Letter: Eosinophilia in bronchogenic carcinoma.", "content": "Letter: Eosinophilia in bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365395"}
{"pmid": "4365394", "title": "Editorial: Problems in receptor identification: catecholamines.", "content": "Editorial: Problems in receptor identification: catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365394"}
{"pmid": "4365396", "title": "Nerve conduction velocity in patients on long-term diphenylhydantoin therapy.", "content": "Nerve conduction velocity in patients on long-term diphenylhydantoin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365396"}
{"pmid": "4365397", "title": "Uptake of the neurotransmitter candidate glutamate by glia.", "content": "Uptake of the neurotransmitter candidate glutamate by glia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365397"}
{"pmid": "4365399", "title": "Effect of Sendai virus on the respiration of rabbit spermatozoa.", "content": "Effect of Sendai virus on the respiration of rabbit spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365399"}
{"pmid": "4365398", "title": "1,25-dihydroxyvitamin D3: a kidney-produced steroid hormone essential to calcium homeostasis.", "content": "1,25-dihydroxyvitamin D3: a kidney-produced steroid hormone essential to calcium homeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365398"}
{"pmid": "4365400", "title": "Editorial: Islet cell tumours of the pancreas.", "content": "Editorial: Islet cell tumours of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365400"}
{"pmid": "4365401", "title": "Cation dependence of high-affinity angiotensin II binding to adrenal cortex receptors.", "content": "Cation dependence of high-affinity angiotensin II binding to adrenal cortex receptors. The specific binding of monoiodinated angiotensin II by particulate receptors from the bovine adrenal cortex is enhanced by addition of sodium and potassium ions, but not other cations. In the presence of 140 millimolar sodium, increased uptake of angiotensin II by adrenal receptors is associated with the appearance of high-affinity binding sites with an association constant of 2 x 10(9) liters per mole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365401"}
{"pmid": "4365403", "title": "The ubiquity of type-C viruses in spargana of Spirometra spp.", "content": "The ubiquity of type-C viruses in spargana of Spirometra spp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365403"}
{"pmid": "4365402", "title": "Incrementing responses in myasthenia gravis.", "content": "Incrementing responses in myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365402"}
{"pmid": "4365404", "title": "Recovery following cranial nerve dysfunction and muscle weakness in infancy.", "content": "Recovery following cranial nerve dysfunction and muscle weakness in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365404"}
{"pmid": "4365405", "title": "Letter: Surgical correction of islet cell carcinoma in a dog.", "content": "Letter: Surgical correction of islet cell carcinoma in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365405"}
{"pmid": "4365407", "title": "NADH- and N2-oxidation in hydrogen bacteria studied by respiratory chain inhibitors.", "content": "NADH- and N2-oxidation in hydrogen bacteria studied by respiratory chain inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365407"}
{"pmid": "4365408", "title": "Comparison of 13C spin-lattice relaxation times in phospholipid vesicles and mutilayers.", "content": "Comparison of 13C spin-lattice relaxation times in phospholipid vesicles and mutilayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365408"}
{"pmid": "4365410", "title": "Ultrastructural studies of periostracum formation in the hard shelled clam Mercenaria mercenaria (L).", "content": "Ultrastructural studies of periostracum formation in the hard shelled clam Mercenaria mercenaria (L).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365410"}
{"pmid": "4365406", "title": "Regulation of aspartokinase activity in non-fermentative, marine eubacteria.", "content": "Regulation of aspartokinase activity in non-fermentative, marine eubacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365406"}
{"pmid": "4365409", "title": "EPR studies on the mechanism of action of succinate dehydrogenase in activated preparations.", "content": "EPR studies on the mechanism of action of succinate dehydrogenase in activated preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365409"}
{"pmid": "4365411", "title": "The rapid separation and isolation of mono- and oligonucleotides by high speed liquid chromatography: an ion exchange, reversed-phase system.", "content": "The rapid separation and isolation of mono- and oligonucleotides by high speed liquid chromatography: an ion exchange, reversed-phase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365411"}
{"pmid": "4365412", "title": "Guanosine 3', 5'-cyclic monophosphate phosphodiesterase activity of Bacillus licheniformis.", "content": "Guanosine 3', 5'-cyclic monophosphate phosphodiesterase activity of Bacillus licheniformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365412"}
{"pmid": "4365413", "title": "Resolution of two protein kinase modulators from lactating rat mammary gland.", "content": "Resolution of two protein kinase modulators from lactating rat mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365413"}
{"pmid": "4365414", "title": "Acetylcholine causes a net decrease in phosphatidylinositol and a net increase in phosphatidic acid in mouse pancreas.", "content": "Acetylcholine causes a net decrease in phosphatidylinositol and a net increase in phosphatidic acid in mouse pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365414"}
{"pmid": "4365415", "title": "Comparative studies on composition of liver phospholipids from rats fed oleic or elaidic acid.", "content": "Comparative studies on composition of liver phospholipids from rats fed oleic or elaidic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365415"}
{"pmid": "4365416", "title": "Evidence for a regulatory function related to the expression of the polyoma genome following the onset of virus DNA replication.", "content": "Evidence for a regulatory function related to the expression of the polyoma genome following the onset of virus DNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365416"}
{"pmid": "4365418", "title": "The nucleic acids of viruses.", "content": "The nucleic acids of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365418"}
{"pmid": "4365417", "title": "Effect of X537A on the release of amino acids in retina.", "content": "Effect of X537A on the release of amino acids in retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365417"}
{"pmid": "4365419", "title": "Cytomegaloviruses.", "content": "Cytomegaloviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365419"}
{"pmid": "4365420", "title": "Selective and reversible inhibition of initiation of protein synthesis in mammalian cells.", "content": "Selective and reversible inhibition of initiation of protein synthesis in mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365420"}
{"pmid": "4365421", "title": "Mating reaction in Saccharomyces cerevisiae. V. Changes in the fine structure during the mating reaction.", "content": "Mating reaction in Saccharomyces cerevisiae. V. Changes in the fine structure during the mating reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365421"}
{"pmid": "4365422", "title": "Liver circulation.", "content": "Liver circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365422"}
{"pmid": "4365423", "title": "Role of silicon in diatom metabolism. V. Silicic acid transport and metabolism in the heterotrophic diatom Nitzschia alba.", "content": "Role of silicon in diatom metabolism. V. Silicic acid transport and metabolism in the heterotrophic diatom Nitzschia alba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365423"}
{"pmid": "4365424", "title": "Electron microscope studies on spermiogenesis in various animal species.", "content": "Electron microscope studies on spermiogenesis in various animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365424"}
{"pmid": "4365425", "title": "Comparative studies of the juxtaglomerular apparatus.", "content": "Comparative studies of the juxtaglomerular apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365425"}
{"pmid": "4365427", "title": "Micronuclei in mouse bone-marrow cells. A simple in vivo model for the evaluation of drug-induced chromosomal aberrations.", "content": "Micronuclei in mouse bone-marrow cells. A simple in vivo model for the evaluation of drug-induced chromosomal aberrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365427"}
{"pmid": "4365428", "title": "The uvrC  gene in Salmonella: phenotypic properties and a preliminary mapping.", "content": "The uvrC  gene in Salmonella: phenotypic properties and a preliminary mapping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365428"}
{"pmid": "4365429", "title": "Herpes simplex.", "content": "Herpes simplex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365429"}
{"pmid": "4365431", "title": "Paul-Bunnell-Davidsohn antibody of infectious mononucleosis and Epstein-Barr virus.", "content": "Paul-Bunnell-Davidsohn antibody of infectious mononucleosis and Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365431"}
{"pmid": "4365435", "title": "Proliferation of arterial cells in atherosclerosis.", "content": "Proliferation of arterial cells in atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365435"}
{"pmid": "4365433", "title": "Concurrence of multiple sclerosis and glioma.", "content": "Concurrence of multiple sclerosis and glioma. Three cases are reported of concurrence of malignant gliomas (astrocytomas and glioblastomas) with multiple sclerosis (MS). This situation may lead to considerable diagnostic difficulties, yet an accurate appraisal is of prognostic, if not therapeutic, value. There is suggestive but inconclusive evidence that the two conditions may be causally related, malignant astrocytic tumours arising from plaques of MS. The small number of reported cases makes statistical analysis impossible, but the scanty literature may not reflect the true incidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365433"}
{"pmid": "4365436", "title": "Thrombosis and connective tissue interrelationships in arteriosclerosis.", "content": "Thrombosis and connective tissue interrelationships in arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365436"}
{"pmid": "4365434", "title": "Reaction patterns of intimal mesenchyme to injury, and repair in atherosclerosis.", "content": "Reaction patterns of intimal mesenchyme to injury, and repair in atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365434"}
{"pmid": "4365438", "title": "Distribution of some possible intermediates of the haem biosynthesis.", "content": "Distribution of some possible intermediates of the haem biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365438"}
{"pmid": "4365426", "title": "Hepatography: distribution of the oily contrast medium after intrasplenic and intravenous (mesenteric) injection.", "content": "Hepatography: distribution of the oily contrast medium after intrasplenic and intravenous (mesenteric) injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365426"}
{"pmid": "4365440", "title": "Enzymes of glycerol metabolism in developing rat liver and kidney.", "content": "Enzymes of glycerol metabolism in developing rat liver and kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365440"}
{"pmid": "4365439", "title": "Androgen receptors in rat testis.", "content": "Androgen receptors in rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365439"}
{"pmid": "4365441", "title": "Protein-prednisolone interaction in the regulation of the activity of some liver and kidney enzymes in growth-plateaued rats.", "content": "Protein-prednisolone interaction in the regulation of the activity of some liver and kidney enzymes in growth-plateaued rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365441"}
{"pmid": "4365442", "title": "Kinetics of the photo-induced EPR signal in whole-cell Rhodospirillum rubrum: effects of light intensity, dark adaptation, temperature, and microwave power.", "content": "Kinetics of the photo-induced EPR signal in whole-cell Rhodospirillum rubrum: effects of light intensity, dark adaptation, temperature, and microwave power.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365442"}
{"pmid": "4365443", "title": "An ultrastructural study of silica deposition in the freshwater sponge Spongilla lacustris.", "content": "An ultrastructural study of silica deposition in the freshwater sponge Spongilla lacustris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365443"}
{"pmid": "4365444", "title": "Benign clear cell tumor of lung.", "content": "Benign clear cell tumor of lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365444"}
{"pmid": "4365445", "title": "Absence of adenine nucleotide release from autonomic ganglion.", "content": "Absence of adenine nucleotide release from autonomic ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365445"}
{"pmid": "4365448", "title": "Antioestrogens in treatment of breast cancer.", "content": "Antioestrogens in treatment of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365448"}
{"pmid": "4365446", "title": "Editorial: Treatment of genital herpes.", "content": "Editorial: Treatment of genital herpes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365446"}
{"pmid": "4365449", "title": "The bacterial etiology of pneumatosis cystoides intestinalis.", "content": "The bacterial etiology of pneumatosis cystoides intestinalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365449"}
{"pmid": "4365451", "title": "The effects of acetylcholine and of synaptic stimulation on the sensorimotor cortex of cats. II. Comparison of the neuronal responses to reticular and other stimuli.", "content": "The effects of acetylcholine and of synaptic stimulation on the sensorimotor cortex of cats. II. Comparison of the neuronal responses to reticular and other stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365451"}
{"pmid": "4365454", "title": "Amino acid release from isolated rat dorsal root ganglia.", "content": "Amino acid release from isolated rat dorsal root ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365454"}
{"pmid": "4365453", "title": "p-Chlorophenylalanine treatment in developing rats: protein and lipids in whole brain and myelin.", "content": "p-Chlorophenylalanine treatment in developing rats: protein and lipids in whole brain and myelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365453"}
{"pmid": "4365456", "title": "Effects from the somatic sensory cortex on transmission through the spinocervical tract.", "content": "Effects from the somatic sensory cortex on transmission through the spinocervical tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365456"}
{"pmid": "4365455", "title": "Effect of dorsal root section on amino acids of rat spinal cord.", "content": "Effect of dorsal root section on amino acids of rat spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365455"}
{"pmid": "4365457", "title": "Comparison of purified lactate dehydrogenases from normal rat liver and Morris hepatomas in rats and in culture.", "content": "Comparison of purified lactate dehydrogenases from normal rat liver and Morris hepatomas in rats and in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365457"}
{"pmid": "4365458", "title": "Microglia and reactive \"M\" cells of degenerating central nervous system: does similar morphology and function imply a common origin?", "content": "Microglia and reactive \"M\" cells of degenerating central nervous system: does similar morphology and function imply a common origin?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365458"}
{"pmid": "4365459", "title": "The effect of slow freezing and hypertonic NaCl on the hydrolytic activity of rat erythrocyte cyclic AMP phosphodiesterase and its sensitivity to the inhibitor, D,L-4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone.", "content": "The effect of slow freezing and hypertonic NaCl on the hydrolytic activity of rat erythrocyte cyclic AMP phosphodiesterase and its sensitivity to the inhibitor, D,L-4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365459"}
{"pmid": "4365460", "title": "Further observations on urethral chromaffin cells: an electron microscopic study.", "content": "Further observations on urethral chromaffin cells: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365460"}
{"pmid": "4365461", "title": "Characteristics of murine C-type viruses. I. Independent assortment of infectivity in one in vivo and four in vitro assays.", "content": "Characteristics of murine C-type viruses. I. Independent assortment of infectivity in one in vivo and four in vitro assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365461"}
{"pmid": "4365462", "title": "Study by the isotopic antiglobulin technique of a cross-reacting murine antibody produced by immunization with a syngeneic SV40 tumor.", "content": "Study by the isotopic antiglobulin technique of a cross-reacting murine antibody produced by immunization with a syngeneic SV40 tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365462"}
{"pmid": "4365464", "title": "The distribution of the sensory input in the dorsal spinal cord of the tortoise.", "content": "The distribution of the sensory input in the dorsal spinal cord of the tortoise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365464"}
{"pmid": "4365466", "title": "Effect of angiotensin II on blood volume and water intake in the rat.", "content": "Effect of angiotensin II on blood volume and water intake in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365466"}
{"pmid": "4365465", "title": "Composition drift in the cytochrome c cistron.", "content": "Composition drift in the cytochrome c cistron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365465"}
{"pmid": "4365467", "title": "Induction and complementation of lysine auxotrophs in Saccharomyces.", "content": "Induction and complementation of lysine auxotrophs in Saccharomyces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365467"}
{"pmid": "4365469", "title": "Cellular lipoproteins, calcium and magnesium in Novikoff hepatoma, liver of tumor-bearing and liver of normal rats.", "content": "Cellular lipoproteins, calcium and magnesium in Novikoff hepatoma, liver of tumor-bearing and liver of normal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365469"}
{"pmid": "4365468", "title": "Interrelations between sulfate-reducing and methane-producing bacteria in bottom deposits of a fresh-water lake. II. Inhibition experiments.", "content": "Interrelations between sulfate-reducing and methane-producing bacteria in bottom deposits of a fresh-water lake. II. Inhibition experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365468"}
{"pmid": "4365475", "title": "I-active antigen of human erythrocyte membrane.", "content": "I-active antigen of human erythrocyte membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365475"}
{"pmid": "4365474", "title": "Streptozotocin treatment for malignant insulinoma.", "content": "Streptozotocin treatment for malignant insulinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365474"}
{"pmid": "4365481", "title": "Studies on experimental lymphoma induced by Herpesvirus saimiri in nonhuman primates. Introduction to the symposium.", "content": "Studies on experimental lymphoma induced by Herpesvirus saimiri in nonhuman primates. Introduction to the symposium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365481"}
{"pmid": "4365482", "title": "Oncogenic herpesviruses in species other than owl monkeys. A review.", "content": "Oncogenic herpesviruses in species other than owl monkeys. A review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365482"}
{"pmid": "4365479", "title": "Chromatin-associated receptors for estrogen, progesterone, and dihydrotestosterone and the induction of egg white protein synthesis in chick magnum.", "content": "Chromatin-associated receptors for estrogen, progesterone, and dihydrotestosterone and the induction of egg white protein synthesis in chick magnum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365479"}
{"pmid": "4365488", "title": "The polypeptide composition of the encephalomyocarditis virus particle.", "content": "The polypeptide composition of the encephalomyocarditis virus particle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365488"}
{"pmid": "4365487", "title": "A serological study on mentally ill patients with particular reference to the prevalence of herpes virus infections.", "content": "A serological study on mentally ill patients with particular reference to the prevalence of herpes virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365487"}
{"pmid": "4365477", "title": "Synthesis and morphogenetic activity of derivaties and analogs of aryl geranyl ether juvenoids.", "content": "Synthesis and morphogenetic activity of derivaties and analogs of aryl geranyl ether juvenoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365477"}
{"pmid": "4365489", "title": "Nuclear localization and covalent linkage of infective virus DNA to chromosomal DNA of non-producer Rous sarcoma cells.", "content": "Nuclear localization and covalent linkage of infective virus DNA to chromosomal DNA of non-producer Rous sarcoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365489"}
{"pmid": "4365490", "title": "Inhibition of simian virus 40 DNA synthesis by frog virus 3.", "content": "Inhibition of simian virus 40 DNA synthesis by frog virus 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365490"}
{"pmid": "4365491", "title": "Inhibition of rhinovirus RNA synthesis in diploid cells by a substituted guanidine compound having a different mode of action from guanidine.", "content": "Inhibition of rhinovirus RNA synthesis in diploid cells by a substituted guanidine compound having a different mode of action from guanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365491"}
{"pmid": "4365478", "title": "A microcolumn apparatus for rapid cleanup of 2,4-dinitrophenylmethylamine extracts for carbamate pesticide analysis.", "content": "A microcolumn apparatus for rapid cleanup of 2,4-dinitrophenylmethylamine extracts for carbamate pesticide analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365478"}
{"pmid": "4365497", "title": "Alteration of fermentation products from butyrate to acetate by nitrate reduction in Clostridium perfringens.", "content": "Alteration of fermentation products from butyrate to acetate by nitrate reduction in Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365497"}
{"pmid": "4365498", "title": "Sensitivity of mesenteric vascular bed to vasoconstrictor drugs during reactive hyperemia.", "content": "Sensitivity of mesenteric vascular bed to vasoconstrictor drugs during reactive hyperemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365498"}
{"pmid": "4365499", "title": "Partially coated vacuoles--a new type of endocytotic structure.", "content": "Partially coated vacuoles--a new type of endocytotic structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365499"}
{"pmid": "4365501", "title": "The mechanism of action of methionyl-tRNA synthetase from Escherichia coli. Mechanism of the amino-acid activation reaction catalyzed by the native and the trypsin-modified enzymes.", "content": "The mechanism of action of methionyl-tRNA synthetase from Escherichia coli. Mechanism of the amino-acid activation reaction catalyzed by the native and the trypsin-modified enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365501"}
{"pmid": "4365502", "title": "Myocardial energy metabolism.", "content": "Myocardial energy metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365502"}
{"pmid": "4365504", "title": "Letter: 14-Sec and 6-sec spikes on sleep EEG as normal finding in stage REM.", "content": "Letter: 14-Sec and 6-sec spikes on sleep EEG as normal finding in stage REM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365504"}
{"pmid": "4365503", "title": "Energy sources of cardiac contraction.", "content": "Energy sources of cardiac contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365503"}
{"pmid": "4365506", "title": "Cyclic nucleotide phosphodiesterase of Chlamydomonas reinhardtii.", "content": "Cyclic nucleotide phosphodiesterase of Chlamydomonas reinhardtii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365506"}
{"pmid": "4365507", "title": "Transformation of mouse cells infected with AKR leukemia virus by benzene extact fractions of city air particles.", "content": "Transformation of mouse cells infected with AKR leukemia virus by benzene extact fractions of city air particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365507"}
{"pmid": "4365505", "title": "Effects of sodium acetate and sodium chloride on EMS-induced chlorophyll mutations in barley.", "content": "Effects of sodium acetate and sodium chloride on EMS-induced chlorophyll mutations in barley.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365505"}
{"pmid": "4365509", "title": "Comparison of dihydrotachysterol and 5,6-trans vitamin D3 on intestinal calcium absorption in patients with chronic renal failure.", "content": "Comparison of dihydrotachysterol and 5,6-trans vitamin D3 on intestinal calcium absorption in patients with chronic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365509"}
{"pmid": "4365508", "title": "Biochemical reactions involved in pancreatic enzyme secretion. I. Activation of the adenylate cyclase complex.", "content": "Biochemical reactions involved in pancreatic enzyme secretion. I. Activation of the adenylate cyclase complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365508"}
{"pmid": "4365511", "title": "Proceedings: 67Ga citrate liver scanning: evaluation of its use in 80 patients and evidence of intrahepatic distribution by autoradiography.", "content": "Proceedings: 67Ga citrate liver scanning: evaluation of its use in 80 patients and evidence of intrahepatic distribution by autoradiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365511"}
{"pmid": "4365510", "title": "Collagen proline hydroxylase activity and 35S sulphate uptake in human liver biopsies.", "content": "Collagen proline hydroxylase activity and 35S sulphate uptake in human liver biopsies. In an effort to assess connective tissue biosynthetic activity in human liver disease, collagen proline hydroxylase (a key enzyme in collagen biosynthesis) and the uptake of (35)S sulphate (a precursor of sulphated mucopolysaccharides) were measured in hepatic tissue obtained mainly by percutaneous biopsy.A procedure is described for the quantitation of collagen proline hydroxylase in cryostat sections which allows for the simultaneous histopathological examination of the liver specimen. A three to eightfold increase in the activity of this enzyme was found in four cirrhotic livers compared with the mean value of four normal livers and two biopsies from patients with Gilbert's syndrome. Elevated hydroxylase levels were found also in five patients with hepatic dysfunction but without cirrhosis (four alcoholics and one patient with persistent hepatitis associated with serum smooth muscle antibody). It is suggested that the hepatic level of collagen proline hydroxylase may be a useful quantitative index of fibroblastic activity in human liver disease. Autoradiographic studies of radioactive sulphate uptake in biopsy specimens from patients with chronic liver disease showed an exaggerated incorporation of isotope not only at sites of established fibrogenesis but also in the walls of sinusoids throughout the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365510"}
{"pmid": "4365512", "title": "Proceedings: Primary liver cell carcinoma: alcohol and chronic liver disease.", "content": "Proceedings: Primary liver cell carcinoma: alcohol and chronic liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365512"}
{"pmid": "4365513", "title": "Cell surface antigens of a mouse testicular teratoma. Identification of an antigen physically associated with H-2 antigens on tumor cells.", "content": "Cell surface antigens of a mouse testicular teratoma. Identification of an antigen physically associated with H-2 antigens on tumor cells. Rabbit antisera to a mouse testicular teratoma, absorbed with normal mouse tissues, react by immunofluorescence with plasma membrane antigens of a variety of transplantable mouse tumor cells and transformed fibroblast cell lines including Clone 1D, SV-40-3T3, and 3T12. Trypsin treatment of cells of \"normal\" lines, 3T3 and FR-SV-3T3, uncovers reactivity on these as well. Early passage mouse embryo fibroblast cell cultures do not react even after trypsinization. By cross-absorbtion studies, the anti-teratoma serum appears to react with an antigen common to most tumor cells investigated thus far. When this antigen on Clone 1D cells is \"capped,\" H-2 antigens collect with the teratoma antigens in the cap indicating a physical association between the molecules. Molecules specified by both the H-2D and H-2K regions are bound to the teratoma antigens in the Clone 1D plasma membrane. This antigen is also found in soluble tumor cell fractions where it is believed to be free of H-2. A second cell surface antigen defined by anti-teratoma serum is expressed only by hepatoma and teratoma itself. This second antigen is apparently a secretory product of teratoma cells. A third surface antigen defined by anti-teratoma serum appears to be specific for the teratoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365513"}
{"pmid": "4365514", "title": "Mutants of nonproducer cell lines transformed by murine sarcoma virus. 3. Detection and characterization of RNA specific for helper and sarcoma viruses.", "content": "Mutants of nonproducer cell lines transformed by murine sarcoma virus. 3. Detection and characterization of RNA specific for helper and sarcoma viruses. BALB/3T3 cells transformed by the Kirsten sarcoma virus (nonvirus producer BALB/3T3 cells) and mutant cell lines derived therefrom by treatment with bromodeoxyuridine (BrdU) were analyzed for expression of virus-specific RNA using single-stranded DNA transcripts of Rauscher leukemia virus (RLV), a virus activated in one of the cell lines (58-2T), and Ki-SV-specific DNA transcript; the latter transcript after removal of all sequences cross-reactive with RLV RNA. The Rauscher virus DNA detected multiple copies of viral RNA in virus-producing cells ( approximately 2.5 x 10(3)/cell) whether infected with RLV or activated to produce virus with BrdU. Nonproducer (NP) cells and normal BALB cells showed small numbers of RNA genomes (70-250/cell) and only partial saturation of the transcript. The intracellular RNA sedimented at 35S (main peak) with a variable minor peak at 20S with the exception of one mutant cell, M-43-2 (main peak at 26-27S). The 58-2T transcript reacted preferentially in NP cells and their derivatives with biphasic kinetics suggesting the possibility of sequences specific for the original transforming virus. The size of Ki-SV specific sequences were 30S in mutant cells whether or not complete virus was being produced and independent of in vivo transplantability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365514"}
{"pmid": "4365515", "title": "Mediation of immunologic discharge of lysosomal enzymes from human neutrophils by guanosine 3',5'-monophosphate. Requirement of calcium, and inhibition by adenosine 3',5'-monophosphate.", "content": "Mediation of immunologic discharge of lysosomal enzymes from human neutrophils by guanosine 3',5'-monophosphate. Requirement of calcium, and inhibition by adenosine 3',5'-monophosphate. The purpose of this investigation was to elucidate the relationship of cyclic GMP and calcium to the immunologic discharge of lysosomal enzymes from purified human neutrophils. Contact of neutrophils with a variety of immunologic stimuli, including zymosan particles treated with either normal or rheumatoid arthritic (RA) serum, heat-aggregated (agg) IgG, particulate and immobilized agg IgG each treated with RA serum, and zymosan-treated serum, provoked the discharge of beta-glucuronidase, but not cytoplasmic lactate dehydrogenase, and stimulated the accumulation of cyclic GMP. Both enzyme release and elevation of cyclic GMP levels required the presence of extracellular calcium as neither cellular event proceeded in its absence. Cholinergic enhancement of the immunologic secretion of beta-glucuronidase from neutrophils by acetylcholine was associated with a concomitant accumulation of cyclic GMP. These actions of acetylcholine on neutrophils did not proceed in the absence of extracellular calcium. Whereas the concentrations of cyclic GMP in neutrophils were elevated by both immune reactants and a combination of the latter and acetylcholine, cyclic AMP levels remained unaltered. Thus, cyclic GMP, but not cyclic AMP, was associated with the immunologic and pharmacologic discharge of lysosomal enzymes from neutrophils. Contrariwise, cyclic AMP, but not cyclic GMP, was associated with inhibition of lysosomal enzyme release. For example, dibutyryl cyclic AMP and epinephrine inhibited the release of beta-glucuronidase from neutrophils that was elicited by each of the immune reactants tested. Moreover, cyclic AMP levels in the cells were elevated markedly in every instance that enzyme discharge was inhibited by epinephrine. Epinephrine did not alter the neutrophil concentrations of cyclic GMP at times when those of cyclic AMP were elevated. The data in this report constitute partial evidence that the immunologic discharge of lysosomal enzymes from human neutrophils is mediated or signaled by intracellular cyclic GMP and that calcium is linked to this stimulation of enzyme secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365515"}
{"pmid": "4365516", "title": "Ultrastructure of xanthelasma palpebrarum as revealed by freeze etching techniques.", "content": "Ultrastructure of xanthelasma palpebrarum as revealed by freeze etching techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365516"}
{"pmid": "4365519", "title": "Pathogenesis of infectious bovine rhinotracheitis (IBR) virus infection in bovine fetal tracheal organ cultures.", "content": "Pathogenesis of infectious bovine rhinotracheitis (IBR) virus infection in bovine fetal tracheal organ cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365519"}
{"pmid": "4365520", "title": "Studies on the unmasking and-or carrier effects of vesicular stomatitis virus grown in human lymphocytes.", "content": "Studies on the unmasking and-or carrier effects of vesicular stomatitis virus grown in human lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365520"}
{"pmid": "4365521", "title": "Pancreatitis of mice infected with encephalomyocarditis virus.", "content": "Pancreatitis of mice infected with encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365521"}
{"pmid": "4365523", "title": "In vitro effects of synthetic somatotropin-release inhibiting factor on cyclic AMP level and GH release in rat anterior pituitary gland.", "content": "In vitro effects of synthetic somatotropin-release inhibiting factor on cyclic AMP level and GH release in rat anterior pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365523"}
{"pmid": "4365525", "title": "A papovavirus isolated from patients with progressive multifocal leukoencephalopathy.", "content": "A papovavirus isolated from patients with progressive multifocal leukoencephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365525"}
{"pmid": "4365527", "title": "Editorial: Bronchial asthma.", "content": "Editorial: Bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365527"}
{"pmid": "4365528", "title": "Mixed tumour in an ectopic salivary gland.", "content": "Mixed tumour in an ectopic salivary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365528"}
{"pmid": "4365529", "title": "Editorial: Japanese encephalitis in India.", "content": "Editorial: Japanese encephalitis in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365529"}
{"pmid": "4365530", "title": "The distribution of 14C-label in the lipids of ram semen following the intratesticular injection of (1-14C)palmitic acid.", "content": "The distribution of 14C-label in the lipids of ram semen following the intratesticular injection of (1-14C)palmitic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365530"}
{"pmid": "4365526", "title": "Virus antibodies in patients with multiple sclerosis.", "content": "Virus antibodies in patients with multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365526"}
{"pmid": "4365531", "title": "Actions of antifertility chemicals on Xenopus laevis spermatozoa in vitro.", "content": "Actions of antifertility chemicals on Xenopus laevis spermatozoa in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365531"}
{"pmid": "4365533", "title": "Relation of nucleoside transport and surface phosphohydrolase activity in Hymenolepis diminuta.", "content": "Relation of nucleoside transport and surface phosphohydrolase activity in Hymenolepis diminuta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365533"}
{"pmid": "4365532", "title": "Interaction of prostaglandins E1 and E2 in regulation of cyclic-AMP and aggregation in human platelets: evidence for a common prostaglandin receptor.", "content": "Interaction of prostaglandins E1 and E2 in regulation of cyclic-AMP and aggregation in human platelets: evidence for a common prostaglandin receptor. The effects of (PGE) prostaglandins E1 and E2 on the aggregation and release reaction induced in human platelets by ADP have been investigated.  Measurements of cyclic-AMP content in (PRP) platelet-rich plasma were made concurrently.  Although both PGE1 and PGE2 independently increased platelet cyclic-AMP and inhibited 1st phase ADP-induced aggregation (order of potency, PGE1  PGE2), the effect of a fixed concentration of PGE2 in the presence of PGE1 varied.  At low PGE1 concentrations, the effects were additive, but at higher PGE1 concentrations PGE2 lowered the efficacy of PGE1.  These results suggest that PGE2 may be a \"partial agonist\" of PGE1.  PGE2 enhanced and PGE1 inhibited the 2nd phase of ADP-induced aggregation and the release of serotonin by a mechanism which appeared to be independent of cyclic-AMP content.  A mixture of the 2 PGs produced responses intermediate between those observed with each PG independently.  Binding of PGE1-3H to platelets was demonstrated in PRP and in concentrated platelet suspensions.  PGE1 and PGE2 inhibited binding in a simular manner.  It is proposed that PGE1 and PGE2 compete for a common receptor on the platelet membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365532"}
{"pmid": "4365534", "title": "On the treatment with proflavine of herpes simplex or vaccinia infected GMK cells. An electron microscopic study.", "content": "On the treatment with proflavine of herpes simplex or vaccinia infected GMK cells. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365534"}
{"pmid": "4365535", "title": "Genetic control of some metabolic modifications during the sporulation of Saccharomyces cerevisiae Hansen.", "content": "Genetic control of some metabolic modifications during the sporulation of Saccharomyces cerevisiae Hansen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365535"}
{"pmid": "4365536", "title": "Influence of dilution rate on enzyme synthesis in Aspergillus niger in continuous culture.", "content": "Influence of dilution rate on enzyme synthesis in Aspergillus niger in continuous culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365536"}
{"pmid": "4365538", "title": "Aminoacyl-tRNA synthetases: sone recent results and achievements.", "content": "Aminoacyl-tRNA synthetases: sone recent results and achievements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365538"}
{"pmid": "4365539", "title": "Clinical care of nonhuman primates. Synopsis and evaluation of a workshop held at the National Institutes of Health, Bethesda, MD., 7-8 March 1973.", "content": "Clinical care of nonhuman primates. Synopsis and evaluation of a workshop held at the National Institutes of Health, Bethesda, MD., 7-8 March 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365539"}
{"pmid": "4365540", "title": "Methods for the separation of platelets from plasma. A comparison of functional and morphological integrity.", "content": "Methods for the separation of platelets from plasma. A comparison of functional and morphological integrity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365540"}
{"pmid": "4365537", "title": "Enzymes of arginine biosynthesis and their repressive control.", "content": "Enzymes of arginine biosynthesis and their repressive control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365537"}
{"pmid": "4365541", "title": "The influence of benzamidine derivatives on human platelet function.", "content": "The influence of benzamidine derivatives on human platelet function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365541"}
{"pmid": "4365542", "title": "Time of appearance of the distal sesamoidean loci of ossification of the calf.", "content": "Time of appearance of the distal sesamoidean loci of ossification of the calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365542"}
{"pmid": "4365543", "title": "Rapid identification of swine vesicular disease virus in vesicular epithelium using the fluorescent antibody technique.", "content": "Rapid identification of swine vesicular disease virus in vesicular epithelium using the fluorescent antibody technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365543"}
{"pmid": "4365544", "title": "Bacterial attack on phenolic ethers. Electron acceptor-substrate binding proteins in bacterial O-dealkylases: purification and characterization of cytochrome P-450npd of Nocardia.", "content": "Bacterial attack on phenolic ethers. Electron acceptor-substrate binding proteins in bacterial O-dealkylases: purification and characterization of cytochrome P-450npd of Nocardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365544"}
{"pmid": "4365546", "title": "The effects of an elevated temperature, colchicine, and vinblastine on axonal microtubules of the crayfish (Procambarus clarkii).", "content": "The effects of an elevated temperature, colchicine, and vinblastine on axonal microtubules of the crayfish (Procambarus clarkii).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365546"}
{"pmid": "4365545", "title": "Biosynthesis of lipovitellin by the crustacean ovary.", "content": "Biosynthesis of lipovitellin by the crustacean ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365545"}
{"pmid": "4365547", "title": "Isolation and characterization of phenothiazine-copper complexes.", "content": "Isolation and characterization of phenothiazine-copper complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365547"}
{"pmid": "4365553", "title": "Purification and biochemical properties of genetically defined malate dehydrogenase in maize.", "content": "Purification and biochemical properties of genetically defined malate dehydrogenase in maize.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365553"}
{"pmid": "4365552", "title": "A Meckel-like syndrome?", "content": "A Meckel-like syndrome?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365552"}
{"pmid": "4365554", "title": "A new procedure for synthesis of 3-keto derivatives of sphingolipids and its application for study of fatty acid composition of brain ceramides and cerebrosides containing dihydrosphingosine of sphingosine.", "content": "A new procedure for synthesis of 3-keto derivatives of sphingolipids and its application for study of fatty acid composition of brain ceramides and cerebrosides containing dihydrosphingosine of sphingosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365554"}
{"pmid": "4365555", "title": "Membrane phospholipids and hormone-sensitive lipolysis in fat cells.", "content": "Membrane phospholipids and hormone-sensitive lipolysis in fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365555"}
{"pmid": "4365556", "title": "Morphological and biochemical studies on liver biopsies of parkinsonian patients treated with levodopa and decarboxylase inhibitor.", "content": "Morphological and biochemical studies on liver biopsies of parkinsonian patients treated with levodopa and decarboxylase inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365556"}
{"pmid": "4365558", "title": "The effect of catecholamines and fasting on cyclic-AMP and release of glycerol from human adipose tissue.", "content": "The effect of catecholamines and fasting on cyclic-AMP and release of glycerol from human adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365558"}
{"pmid": "4365559", "title": "The effect of sex on certain properties of the very low density lipoprotein secreted by the liver.", "content": "The effect of sex on certain properties of the very low density lipoprotein secreted by the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365559"}
{"pmid": "4365560", "title": "Cobalt--bis(histidine methyl ester) deuteroporphyrine IX: a coenzyme B12--related model.", "content": "Cobalt--bis(histidine methyl ester) deuteroporphyrine IX: a coenzyme B12--related model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365560"}
{"pmid": "4365561", "title": "A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity.", "content": "A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365561"}
{"pmid": "4365563", "title": "Phosphoglycerate kinase (GTP). An enzyme from Entamoeba histolytica selective for guanine nucleotides.", "content": "Phosphoglycerate kinase (GTP). An enzyme from Entamoeba histolytica selective for guanine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365563"}
{"pmid": "4365564", "title": "(3H)norepinephrine binding: unrelated to catechol-O-methyl transferase.", "content": "(3H)norepinephrine binding: unrelated to catechol-O-methyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365564"}
{"pmid": "4365562", "title": "Lysophospholipid induced volume changes in lysosomes and in lysosomal lipid dispersions.", "content": "Lysophospholipid induced volume changes in lysosomes and in lysosomal lipid dispersions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365562"}
{"pmid": "4365567", "title": "Editorial: The diagnostic tripod.", "content": "Editorial: The diagnostic tripod.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365567"}
{"pmid": "4365568", "title": "Letter: Test for role of angiotensin in hypertension.", "content": "Letter: Test for role of angiotensin in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365568"}
{"pmid": "4365569", "title": "Regularity in the control of the free-running sleep-wakefulness rhythm.", "content": "Regularity in the control of the free-running sleep-wakefulness rhythm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365569"}
{"pmid": "4365570", "title": "Regulation of melanocyte stimulating hormone action at the receptor level: discontinuous binding of hormone to synchronized mouse melanoma cells during the cell cycle.", "content": "Regulation of melanocyte stimulating hormone action at the receptor level: discontinuous binding of hormone to synchronized mouse melanoma cells during the cell cycle. Melanocyte stimulating hormone coupled to Sepharose effects an increase in tryosinase (EC 1.14.18.1; monophenol monoxygenase) activity of cultivated mouse melanoma cells. Synchronized cells are found to respond to melanocyte stimulating hormone only in the G2 phase of the cell cycle, although their response to cyclic AMP is independent of position in the cell cycle. The binding of (125)I-labeled melanocyte stimulating hormone occurs predominantly in G2. These observations are satisfied by a model in which the hormone can activate adenylate cyclase (EC 4.6.1.1) by binding to a melanocyte stimulating hormone receptor only in G2; the events distal to cyclic AMP production can occur throughout the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365570"}
{"pmid": "4365571", "title": "Non-selective inhibition of transformed cell growth by a protease inhibitor.", "content": "Non-selective inhibition of transformed cell growth by a protease inhibitor. The protease inhibitors N-tosyl-L-phenylalanylchloromethyl ketone (TPCK) and N-tosyl-L-lysylchloromethyl ketone (TLCK) have previously been shown to selectively inhibit growth of simian virus 40-transformed cells, suggesting that proteolytic enzymes play a role in loss of cellular growth control following viral transformation. In contrast, this study shows that TPCK-mediated growth inhibition is non-selective, since the growth of both simian virus 40-transformed and untransformed 3T3 cells is similarly reduced by TPCK treatment. Under certain conditions, TPCK treatment of simian virus 40-transformed cells yields a reversible \"growth plateau\" condition which mimics, but is not equivalent to, contact inhibition of growth. The growth inhibitory effects of TPCK are due to inhibition of protein synthesis, since TPCK treatment resulted in a diminution of protein synthesis and since the \"growth plateau\" effect was also observed in cultures treated with cycloheximide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365571"}
{"pmid": "4365573", "title": "Enzyme activity in invasive tumors of human breast and colon.", "content": "Enzyme activity in invasive tumors of human breast and colon. Elevated levels of glycoprotein:sialyltransferase activity (EC 2.4.99.1; CMP-N-acetylneuraminate: D-galactosyl-glycoprotein N-acetylneuraminyltransferase) were found in human malignant neoplastic tissues compared to normal, benign, and \"preneoplastic\" tissues. This increase was not due to the cell density of the tissue. Elevated levels of certain proteases and glycosidases were also found. The increase in transferase activity may be associated with altered membrane synthesis in the neoplastic state; changes in the activity of degradative enzymes may be associated with tumor invasiveness and maintenance of the neoplastic state. Measurements on human tumors are possibly more directly relevant to cancer than those described for transformed fibroblastic cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365573"}
{"pmid": "4365575", "title": "Guanosine 3':5'-cyclic monophosphate-dependent phosphorylation of endogenous substrate proteins in membranes of mammalian smooth muscle.", "content": "Guanosine 3':5'-cyclic monophosphate-dependent phosphorylation of endogenous substrate proteins in membranes of mammalian smooth muscle. Guanosine 3':5'-cyclic monophosphate (cyclic GMP) stimulated the endogenous phosphorylation of two proteins in isolated membrane fractions from mammalian organs rich in smooth muscle, including ductus deferens, uterus, and small intestine. The apparent molecular weights of the substrate proteins were 130,000 and 100,000. In the presence of 10 mM MnCl(2), a half-maximal increase in phosphorylation of these proteins was achieved with 20-30 nM cyclic GMP. Approximately 10-fold higher concentrations of adenosine 3':5'-cyclic monophosphate (cyclic AMP) were required to produce the same increase in phosphorylation of these two proteins. Cyclic AMP, but not cyclic GMP, regulated the phosphorylation of a third protein present in these same membrane fractions; the apparent molecular weight of this protein was 50,000. Cyclic GMP-dependent phosphorylation of endogenous protein was not observed in the cell sap of any of the three preparations of smooth muscle studied. The finding of endogenous cyclic GMP-dependent protein kinase activity and associated substrate proteins in membrane fractions from several mammalian organs containing smooth muscle raises the possibility that physiological actions of cyclic GMP in smooth muscle may be mediated by the phosphorylation of membrane proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365575"}
{"pmid": "4365576", "title": "Investigation of very slowly tumbling spin labels by nonlinear spin response techniques: theory and experiment for stationary electron electron double resonance.", "content": "Investigation of very slowly tumbling spin labels by nonlinear spin response techniques: theory and experiment for stationary electron electron double resonance. The investigation of very slowly tumbling spin labels by nonlinear electron spin response techniques is discussed. Such techniques permit characterization of rotational processes with correlation times from 10(-3) to 10(-7) sec even though the linear spin response (ESR) technique is insensitive to motion in this region. Nonlinear techniques fall into two categories: (a) Techniques (referred to as passage techniques) in which the distribution of saturation throughout the spin system is determined both by the applied magnetic field modulation of the resonance condition and by the modulation of the resonance frequency induced by the molecular motion. The time dependence of this distribution produces phase and amplitude changes in the observed signals. (b) Techniques that measure the integral of the distribution function of the time required for saturated spin packets to move between pumped and observed portions of the spectrum [stationary and pulsed electron electron double resonance (ELDOR) techniques]. Quantitative analysis of passage ESR and stationary ELDOR techniques can be accomplished employing a density matrix treatment that explicitly includes the interaction of the spins with applied radiation and modulation fields. The effect of molecular motion inducing a random modulation of the anisotropic spin interactions can be calculated by describing the motion by the diffusion equation appropriate to the motional model assumed. For infinitesimal steps the eigen-functions of the diffusion operator are known analytically, while for random motion of arbitrary step size they are determined by diagonalizing the transition matrix appropriate for the step model used. The present communication reports investigation of the rotational diffusion of the spin label probes 2,2,6,6-tetramethyl-4-piperidinol-1-oxyl and 17beta-hydroxy-4',4'-dimethylspiro-[5alpha-androstane-3,2'-oxazolidin]-3'-oxyl in sec-butylbenzene. Experimental spectra are compared with computer simulations of spectra carried out for isotropic Brownian (limit of infinitesimal step size) and free diffusion (arbitrary step size) models.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365576"}
{"pmid": "4365574", "title": "Visualization of single-stranded nucleic acid of RNA tumor virus with the electron microscope.", "content": "Visualization of single-stranded nucleic acid of RNA tumor virus with the electron microscope. 60-70S RNA of avian myeloblastosis virus was spread with the Kleinschmidt method and examined in the electron microscope after being subjected to a variety of denaturing conditions. Extension of the molecules from a collapsed configuration was seen only under stringent denaturing conditions, resulting in molecules of 1-2 mum in length. Longer strands of these extremely fragile molecules cannot be obtained with the methods presently available.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365574"}
{"pmid": "4365572", "title": "Changes in activity and molecular properties of fructose 1, 6-bisphosphatase during fasting and refeeding.", "content": "Changes in activity and molecular properties of fructose 1, 6-bisphosphatase during fasting and refeeding. During prolonged starvation, fructose 1,6bisphosphatase (EC 3.1.3.11) activity in rabbit liver and kidney shows a transient decrease during the first 36 hr, before rising at 96 hr to levels severalfold higher than those found in the livers of fed animals. Proteolytic activity appears in the 105,000 x g supernatant fraction within several hours of starvation, and continues to increase during the entire 96-hr period. On refeeding, the activities return to nearly the control levels within 24 hr. The catalytic properties of fructose 1,6-bisphosphatase isolated from the livers of fasted rabbits are similar to those of the enzyme from fed animals, but its structure is modified, since it no longer contains the single tryptophan residue located near the NH(2)-terminus in the native enzyme. Thus this tryptophan residue is not required for the neutral pH optimum. The structural changes and the transient decrease in activity may be related to the observed increase in \"free\" proteolytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365572"}
{"pmid": "4365577", "title": "Widespread natural occurrence of high titers of neutralizing antibodies to a specific class of endogenous mouse type-C virus.", "content": "Widespread natural occurrence of high titers of neutralizing antibodies to a specific class of endogenous mouse type-C virus. Mouse cells contain several biologically distinguishable endogenous type-C viruses. In the present studies, the immunologic response of different strains of mice to the natural expression of these viruses has been examined. High titers of neutralizing antibodies have been detected to a class of virus that lacks the ability to exogenously infect mouse cells. The expression of this virus, in vivo as well as in vitro, is shown to be vertically transmitted as a dominant genetic trait. The findings indicate the widespread occurrence of this endogenous virus and the ability of the mouse to immunologically respond to a class of type-C virus whose mode of transmission is similar to that of cellular genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365577"}
{"pmid": "4365578", "title": "Accumulation of an intermediate in DNA synthesis by HEp.2 cells treated with methyl methanesulfonate.", "content": "Accumulation of an intermediate in DNA synthesis by HEp.2 cells treated with methyl methanesulfonate. A portion of the DNA synthesized by HEp.2 cells after short incubation in the presence of BrdU bands in a CsCl gradient at a distinct peak of density 1.715-1.718 g/cm(3). Inhibition of DNA synthesis by methyl methanesulfonate results in an increased proportion of this \"intermediate density\" DNA. Cells labeled and subsequently chased in nonradioactive BrdU yield only hybrid DNA. Treatment with single-strand-specific deoxyribonuclease converts a portion of the intermediate density material to molecules of hybrid density (1.755 g/cm(3)). The data suggest an intermediate in DNA replication that contains a single-stranded region in the parental strand and that accumulates when DNA synthesis is blocked by an alkylation-induced lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365578"}
{"pmid": "4365579", "title": "Mechanism of enzymic acetylation of des-acetyl citrate lyase.", "content": "Mechanism of enzymic acetylation of des-acetyl citrate lyase. A new enzyme, acetate:SH-[acyl-carrier-protein] enzyme ligase (AMP), has been purified about 30-fold from cell-free extracts of Klebsiella aerogenes. The enzyme, in the presence of acetate and ATP, catalyzes the acetylation of enzymically inactive des-acetyl citrate lyase to enzymically active citrate lyase (EC 4.1.3.6). Acetate and ATP could be replaced by acetyl adenylate. Acetyl-CoA can act as acetyl donor in this activation only if trace amounts of adenine nucleotides and auxiliary enzymes are present. These allow formation of acetyl adenylate in acetate- and ATP-generating reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365579"}
{"pmid": "4365580", "title": "Differences in membrane fluidity and structure in contact-inhibited and transformed cells.", "content": "Differences in membrane fluidity and structure in contact-inhibited and transformed cells. Studies on contact-inhibited mouse embryo fibroblast 3T3 cells and 3T3 cells transformed by oncogenic RNA and DNA viruses and by a chemical carcinogen have demonstrated differences in plasma membrane architecture. Spin-label and freeze-fracture ultrastructural studies have shown that contact-inhibited cells have ordered membrane lipids and aggregated intramembranous particles, whereas transformed cells have fluid membrane lipids and randomly distributed intramembranous particles. These findings suggest a model for how changes in the cell membrane may account for some of the characteristic differences observed between contact-inhibited and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365580"}
{"pmid": "4365581", "title": "An RNA-dependent nucleoside triphosphate phosphohydrolase (ATPase) associated with rho termination factor.", "content": "An RNA-dependent nucleoside triphosphate phosphohydrolase (ATPase) associated with rho termination factor. Highly purified rho termination factor from Escherichia coli catalyzes an RNA-dependent hydrolysis of ribonucleoside triphosphates to nucleoside diphosphates and inorganic phosphate. In the presence of poly(C), a specific activity of 100 mumole of ATP hydrolyzed per min/mg has been measured. The phosphohydrolase activity appears to be associated with the protein responsible for termination of RNA synthesis, but a functional relationship between the two activities is not yet evident. Hydrolysis of nucleoside triphosphates occurs in the absence of termination and without any extensive degradation of RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365581"}
{"pmid": "4365582", "title": "Spontaneous induction of endogenous murine leukemia virus-related antigen expression during short-term in vitro incubation of mouse lymphocytes.", "content": "Spontaneous induction of endogenous murine leukemia virus-related antigen expression during short-term in vitro incubation of mouse lymphocytes. Short-term lymphocyte cultures from mouse thymus, spleen, or lymph nodes were studied for the presence of murine leukemia virus group-specific antigens with an immunofluorescence test using rat immune sera against syngeneic cells infected with the radiation leukemia virus or its pseudotype of murine sarcoma virus and goat and rabbit antisera against purified murine leukemia virus group-specific antigen. Antigens reacting with these sera appeared in the cultured lymphocytes within 24 hr, and the proportion of immunofluorescent-positive cells increased to 25-80% by the second or third day of cultivation, concomitantly with a decrease in cell viability. The appearance of these antigens can be suppressed by inhibitors of DNA (mitomycin-C), RNA (actinomycin-D, cordycepin, and polyadenylic acid), and protein (cycloheximide) synthesis. No infectious virus could be detected by the immunofluorescence and XC-cell tests. The observed phenomenon appears to represent the spontaneous partial derepression of endogenous murine leukemia virus replication in lymphocytes during short-term in vitro cultivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365582"}
{"pmid": "4365583", "title": "Specific movement of cell membranes fused with HVJ (Sendai virus).", "content": "Specific movement of cell membranes fused with HVJ (Sendai virus). When Ehrlich ascites tumor cells fused with UV-inactivated HVJ (Sendai virus) were cultured, the viral envelope antigens, which had been integrated at random into the cell membranes, accumulated at one site on the fused cell. The site showed a specific structure, namely, a projection of the cytoplasm from the spherical fused cell surface with clusters of many long microvillilike protrusions from it. When the fused cells were conjugated with antibody against Ehrlich ascites tumor cells and cultured, the antigen-antibody complex also accumulated on the projection.Associated with the development of the projection and accumulation of viral antigens, vacuoles developed at the base of the projection in the cytoplasm of the fused cells in culture. The development of the projection and vacuoles and the accumulation of viral antigens were all inhibited by glucose, mannose, galactose, sodium azide, and cycloheximide, and these inhibitions were reversible. All these structures were observed in multinucleated cells, but few in mononucleated cells after reaction with HVJ (Sendai virus). We consider that these three phenomena correlate with each other and may result from changes in cell-membrane systems caused by fusion of cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365583"}
{"pmid": "4365585", "title": "Polyoma DNA: a physical map.", "content": "Polyoma DNA: a physical map. The action of restriction enzymes on polyoma DNA was studied with uniformly (32)P-labeled viral DNA obtained from either infected 3T6 or secondary mouse-embryo cells. Three restriction enzymes were used to construct a physical map of the polyoma genome. An enzyme from Hemophilus parainfluenzae, Hpa(II), cleaved polyma DNA into eight unique fragments (Hpa(II)-1 to Hpa(II)-8), ranging in size from 27.3 to 1.8% of the genome. An enzyme from Hemophilus influenzae, Hin(III), gave two fragments (56 and 44%); and a third enzyme from Escherichia coli, EcoR(I), cut at a single unique site. The physical map of the polyma genome was constructed from methods involving: (1) further digestion of the fragments produced by enzymes EcoR(I) and Hin(III) with Hpa(II), and (2) analysis of the products of partial digestion with Hpa(II). Analysis by electron microscopy of replicating DNA molecules (less than 50% replicated) cut with the Hin(III) enzyme, in combination with other studies, has indicated that the origin of DNA replication is located at 71 +/- 3 map units from the EcoR(I) cleavage site, probably in Hpa(II)-5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365585"}
{"pmid": "4365584", "title": "Discontinuous variability, in the form of a geometric progression, of albumin production in hepatoma and hybrid cells.", "content": "Discontinuous variability, in the form of a geometric progression, of albumin production in hepatoma and hybrid cells. A clonal rat hepatoma cell line (Fu5) produces rat serum albumin at a constant rate over at least 3 months of continuous cultivation. Ten hybrid cell clones derived from the fusion of Fu5 cells and mouse fibroblasts, as well as 14 hepatoma subclones of Fu5 cells, all produce albumin but at different rates, ranging from about 0.09 to 36.7 mug/mg of protein per 72 hr. Despite this variability in albumin production, the distribution of clones is not random but discontinuous, with both hepatoma and hybrid clones clustering around discrete values that can be fitted to the geometric progression: a, a( radical2)(1), a( radical2)(2)..... a( radical2)(n). The values of the majority of clones fall into alternate members of this geometric progression, which differ by a factor of 2. Hepatoma subclones with indistinguishable karyotypes differ in level of albumin production by as much as 4-fold. In contrast to hepatoma clones, albumin production in hybrid clones decreases with increasing cell generations. A survey of 28 enzymes of different hepatomas reveals a large variability in enzyme levels which, for most enzymes, can be arranged into classes that form a geometric progression. The apparent widespread nature of this discontinuous phenotypic variability suggests that it may reflect a basic mechanism of control of gene expression in animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365584"}
{"pmid": "4365586", "title": "Evidence for the in vivo regulation of glucose 6-phosphate dehydrogenase activity in Hydrogenomonas eutropha H 16 from measurements of the intracellular concentrations of metabolic intermediates.", "content": "Evidence for the in vivo regulation of glucose 6-phosphate dehydrogenase activity in Hydrogenomonas eutropha H 16 from measurements of the intracellular concentrations of metabolic intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365586"}
{"pmid": "4365588", "title": "Aspirin and analgin as analgesics.", "content": "Aspirin and analgin as analgesics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365588"}
{"pmid": "4365589", "title": "Carbohydrate transport and cyclic 3',5' adenosine monophosphate (cAMP) levels in a temperature sensitive phosphotransferase mutant of Escherichia coli.", "content": "Carbohydrate transport and cyclic 3',5' adenosine monophosphate (cAMP) levels in a temperature sensitive phosphotransferase mutant of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365589"}
{"pmid": "4365590", "title": "Physiological and endocrinological changes in response to terminal heat stress in swine.", "content": "Physiological and endocrinological changes in response to terminal heat stress in swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365590"}
{"pmid": "4365594", "title": "An autopsy case of isolated myocarditis probably associated with infectious mononucleosis and disseminated cytomegalic inclusion disease.", "content": "An autopsy case of isolated myocarditis probably associated with infectious mononucleosis and disseminated cytomegalic inclusion disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365594"}
{"pmid": "4365596", "title": "Letter: Estrogenic substances in beef.", "content": "Letter: Estrogenic substances in beef.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365596"}
{"pmid": "4365598", "title": "Growth quantitation of human mammary carcinoma in organ tissue culture.", "content": "Growth quantitation of human mammary carcinoma in organ tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365598"}
{"pmid": "4365597", "title": "Genital herpes. Some clinical and laboratory observations.", "content": "Genital herpes. Some clinical and laboratory observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365597"}
{"pmid": "4365599", "title": "Relationship of the adrenergic nervous system and growth hormone release in normal adults and children with various growth disorders.", "content": "Relationship of the adrenergic nervous system and growth hormone release in normal adults and children with various growth disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365599"}
{"pmid": "4365595", "title": "Reciprocal influence of salt intake on adrenal glomerulosa and renal vascular responses to angiotensin II in normal man.", "content": "Reciprocal influence of salt intake on adrenal glomerulosa and renal vascular responses to angiotensin II in normal man. The adrenal glomerulosa cell and the renal vasculature respond to similar arterial angiotensin II (A II) levels. We have assessed the effect of decreased sodium intake on their responses to A II in man. Studies were performed in 42 normal subjects in balance on a daily intake of 100 meq potassium and either 200 or 10 meq sodium/day. Renal blood flow was measured with (133)Xe and arterial A II, renin and aldosterone concentrations by radioimmunoassay. A II was infused intravenously (1, 3, or 10 ng/kg/min) for 40-60 min; 14 subjects received graded doses. The A II level increased linearly with dose and plateaued within 3 min; blood pressure and renal vascular resistance showed a similar time-course. Aldosterone rose within 10 and plateaued within 20 min. Dose-response relationships were established between the rate of A II infusion and the adrenal, the renal vascular, and pressor responses. Sodium restriction reduced the pressor (P < 0.01) and the renal vascular response (P < 0.01), but potentiated the adrenal response to A II (P < 0.01). An excellent correlation was found between the plasma A II and aldosterone levels, but the slope of their regression relationship on a high (y = 0.13x + 6) and low salt intake (y = 0.32x + 14) differed significantly (P < 0.0005). Thus, sodium intake reciprocally influences vascular and adrenal responses to A II: salt restriction blunts the vascular response and potentiates the adrenal's, a physiologically important influence in view of aldosterone's role in sodium conservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365595"}
{"pmid": "4365600", "title": "Renal vein native plasma pressor activity.", "content": "Renal vein native plasma pressor activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365600"}
{"pmid": "4365602", "title": "Isolation of reovirus type 1 from lambs showing respiratory and intestinal symptoms.", "content": "Isolation of reovirus type 1 from lambs showing respiratory and intestinal symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365602"}
{"pmid": "4365603", "title": "Isolation of rhinovirus from cattle in outbreaks of acute respiratory disease.", "content": "Isolation of rhinovirus from cattle in outbreaks of acute respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365603"}
{"pmid": "4365605", "title": "Further characterization of infectious hematopoietic necrosis virus of salmonid fish (Oregon strain).", "content": "Further characterization of infectious hematopoietic necrosis virus of salmonid fish (Oregon strain).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365605"}
{"pmid": "4365607", "title": "Mechanism of bufalin-induced blockade of neuromuscular transmission in isolated rat diaphragm.", "content": "Mechanism of bufalin-induced blockade of neuromuscular transmission in isolated rat diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365607"}
{"pmid": "4365606", "title": "Effects of cytochrome C on the liver function of aged rats.", "content": "Effects of cytochrome C on the liver function of aged rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365606"}
{"pmid": "4365613", "title": "Spectral analysis of hippocampal slow wave activity during feeding and drinking in the rabbit.", "content": "Spectral analysis of hippocampal slow wave activity during feeding and drinking in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365613"}
{"pmid": "4365612", "title": "Sleep patterns in the pony with observations on partial perceptual deprivation.", "content": "Sleep patterns in the pony with observations on partial perceptual deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365612"}
{"pmid": "4365619", "title": "Specific induction of transitions and transversions of G-C base pairs by 4-nitroquinoline-1-oxide in iso-1-cytochrome c mutants of yeast.", "content": "Specific induction of transitions and transversions of G-C base pairs by 4-nitroquinoline-1-oxide in iso-1-cytochrome c mutants of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365619"}
{"pmid": "4365620", "title": "Specificity and frequency of ultraviolet-induced reversion of an iso-1-cytochrome c ochre mutant in radiation-sensitive strains of yeast.", "content": "Specificity and frequency of ultraviolet-induced reversion of an iso-1-cytochrome c ochre mutant in radiation-sensitive strains of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365620"}
{"pmid": "4365621", "title": "Acute suppurative amebic pericarditis.", "content": "Acute suppurative amebic pericarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365621"}
{"pmid": "4365623", "title": "Nuclear receptor estradiol complex: a requirement for uterotrophic responses.", "content": "Nuclear receptor estradiol complex: a requirement for uterotrophic responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365623"}
{"pmid": "4365622", "title": "Inhibition of glucagon-mediated increases in hepatic cyclic adenosine 3', 5'-monophosphate by prostaglandin E1 and E2.", "content": "Inhibition of glucagon-mediated increases in hepatic cyclic adenosine 3', 5'-monophosphate by prostaglandin E1 and E2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365622"}
{"pmid": "4365624", "title": "Initiation of luteinization in rabbit Graafian follicles by dibutyryl cyclic AMP in vitro.", "content": "Initiation of luteinization in rabbit Graafian follicles by dibutyryl cyclic AMP in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365624"}
{"pmid": "4365626", "title": "Proceedings: Further investigations on the effects of adrenalectomy and pituitary-adrenocortical hormone treatments on isolation-induced fighting behaviour in male albino mice.", "content": "Proceedings: Further investigations on the effects of adrenalectomy and pituitary-adrenocortical hormone treatments on isolation-induced fighting behaviour in male albino mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365626"}
{"pmid": "4365627", "title": "Proceedings: Changes in kallikrein excretion during arterial infusion of angiotensin.", "content": "Proceedings: Changes in kallikrein excretion during arterial infusion of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365627"}
{"pmid": "4365625", "title": "Binding of luteinizing hormone and human chorionic gonadotrophin to ovarian cells and activation of adenylate cyclase.", "content": "Binding of luteinizing hormone and human chorionic gonadotrophin to ovarian cells and activation of adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365625"}
{"pmid": "4365628", "title": "Proceedings: Effect of angiotensin II on cyclic AMP and corticosterone output by purified zona glomerulosa and zona fasciculata cells of the rat adrenal cortex.", "content": "Proceedings: Effect of angiotensin II on cyclic AMP and corticosterone output by purified zona glomerulosa and zona fasciculata cells of the rat adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365628"}
{"pmid": "4365629", "title": "Red blood cell drug binding as a possible mechanism for tranquilization.", "content": "Red blood cell drug binding as a possible mechanism for tranquilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365629"}
{"pmid": "4365618", "title": "Responsiveness of lymphocytes from Mengovirus treated mice to phytohaemagglutinin stimulation, in vitro.", "content": "Responsiveness of lymphocytes from Mengovirus treated mice to phytohaemagglutinin stimulation, in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365618"}
{"pmid": "4365630", "title": "Mode of action of mucidin, a new antifungal antibiotic produced by the basidiomycete Oudemansiella mucida.", "content": "Mode of action of mucidin, a new antifungal antibiotic produced by the basidiomycete Oudemansiella mucida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365630"}
{"pmid": "4365632", "title": "Biochemical cytology of trichomonad flagellates. II. Subcellular distribution of oxidoreductases and hydrolases in Monocercomonas sp.", "content": "Biochemical cytology of trichomonad flagellates. II. Subcellular distribution of oxidoreductases and hydrolases in Monocercomonas sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365632"}
{"pmid": "4365631", "title": "Inhibition by several standard antiprotozoal drugs of growth and O2 uptake of cells and particulate preparations of a Leptomonas.", "content": "Inhibition by several standard antiprotozoal drugs of growth and O2 uptake of cells and particulate preparations of a Leptomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365631"}
{"pmid": "4365636", "title": "The renin system: Variations in man measured by radioimmunoassay or bioassay.", "content": "The renin system: Variations in man measured by radioimmunoassay or bioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365636"}
{"pmid": "4365633", "title": "Stimulation of cyclic adenosine 3',5'-monophosphate accumulation and lipolysis in fat cells by adenosine deaminase.", "content": "Stimulation of cyclic adenosine 3',5'-monophosphate accumulation and lipolysis in fat cells by adenosine deaminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365633"}
{"pmid": "4365635", "title": "Renal morphological and immunological changes associated with acute viral hepatitis.", "content": "Renal morphological and immunological changes associated with acute viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365635"}
{"pmid": "4365637", "title": "Enzyme activities of the single juxtaglomerular apparatus in the rat kidney.", "content": "Enzyme activities of the single juxtaglomerular apparatus in the rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365637"}
{"pmid": "4365641", "title": "Exocellular pyruvate-containing galactoglucan of Achromobacter spp.", "content": "Exocellular pyruvate-containing galactoglucan of Achromobacter spp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365641"}
{"pmid": "4365642", "title": "Pinocytotic uptake of protein from the reservoir in Euglena.", "content": "Pinocytotic uptake of protein from the reservoir in Euglena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365642"}
{"pmid": "4365645", "title": "Chromatographic preparation of purified structural proteins from foot-and-mouth disease virus.", "content": "Chromatographic preparation of purified structural proteins from foot-and-mouth disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365645"}
{"pmid": "4365643", "title": "The cytochromes of some hydrogen bacteria.", "content": "The cytochromes of some hydrogen bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365643"}
{"pmid": "4365644", "title": "Bio-degradation and utilization of silica and quartz.", "content": "Bio-degradation and utilization of silica and quartz.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365644"}
{"pmid": "4365646", "title": "Comparison of large fragments obtained by T1 RNase digestion of ribosomal and nucleolar preribosomal RNA of Novikoff hepatoma ascites cells: the 5'-terminal eicosanucleotide.", "content": "Comparison of large fragments obtained by T1 RNase digestion of ribosomal and nucleolar preribosomal RNA of Novikoff hepatoma ascites cells: the 5'-terminal eicosanucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365646"}
{"pmid": "4365648", "title": "Nucleotide clusters in in deoxyribonucleic acids. X. Sequences of the pyrimidine oligonucleotides of mouse L-cell satellite DNA.", "content": "Nucleotide clusters in in deoxyribonucleic acids. X. Sequences of the pyrimidine oligonucleotides of mouse L-cell satellite DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365648"}
{"pmid": "4365649", "title": "Regulation of herpes simplex virus-induced thymidine kinase.", "content": "Regulation of herpes simplex virus-induced thymidine kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365649"}
{"pmid": "4365647", "title": "Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity.", "content": "Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365647"}
{"pmid": "4365653", "title": "Proceedings: Influence of dibutyryl cyclic AMP on the K+-contracture of guinea-pig trachea.", "content": "Proceedings: Influence of dibutyryl cyclic AMP on the K+-contracture of guinea-pig trachea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365653"}
{"pmid": "4365652", "title": "Inactivation of Sabin oral poliomyelitis type I virus.", "content": "Inactivation of Sabin oral poliomyelitis type I virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365652"}
{"pmid": "4365654", "title": "Proceedings: Changes of the level of cyclic AMP in carrageenin granuloma.", "content": "Proceedings: Changes of the level of cyclic AMP in carrageenin granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365654"}
{"pmid": "4365655", "title": "Proceedings: Electrophysiological studies on adenyl cyclase-cyclic AMP system in the fat cell membrane.", "content": "Proceedings: Electrophysiological studies on adenyl cyclase-cyclic AMP system in the fat cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365655"}
{"pmid": "4365656", "title": "Proceedings: Thiamine metabolism in the central nervous system. 2. Effects of psychotropic drugs on rat brain thiamine di- and tri-phosphatase.", "content": "Proceedings: Thiamine metabolism in the central nervous system. 2. Effects of psychotropic drugs on rat brain thiamine di- and tri-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365656"}
{"pmid": "4365658", "title": "Proceedings: Influence of the nucleus dorsalis on neuron activities of the spinal trigeminal nucleus.", "content": "Proceedings: Influence of the nucleus dorsalis on neuron activities of the spinal trigeminal nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365658"}
{"pmid": "4365657", "title": "Proceedings: Relation between hyperkalemia and hyperglycemia. 9.", "content": "Proceedings: Relation between hyperkalemia and hyperglycemia. 9.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365657"}
{"pmid": "4365659", "title": "Proceedings: Influence of the nucleus dorsalis on neuron activities of the spinal trigeminal nucleus.", "content": "Proceedings: Influence of the nucleus dorsalis on neuron activities of the spinal trigeminal nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365659"}
{"pmid": "4365660", "title": "Proceedings: Effects of ATP on sympathetic ganglia from bullfrog.", "content": "Proceedings: Effects of ATP on sympathetic ganglia from bullfrog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365660"}
{"pmid": "4365661", "title": "Proceedings: Biochemical studies on the mechanism of action of a new anti-inflammatory agent, naproxen. 2. Effects of naproxen on mucopolysaccharase, protease and collagenolytic enzyme activities in inflamed tissues of filter paper-implanted rats.", "content": "Proceedings: Biochemical studies on the mechanism of action of a new anti-inflammatory agent, naproxen. 2. Effects of naproxen on mucopolysaccharase, protease and collagenolytic enzyme activities in inflamed tissues of filter paper-implanted rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365661"}
{"pmid": "4365664", "title": "Polyamines in normal and in virus-transformed chick embryo fibroblasts.", "content": "Polyamines in normal and in virus-transformed chick embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365664"}
{"pmid": "4365663", "title": "Ocular findings in leprosy.", "content": "Ocular findings in leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365663"}
{"pmid": "4365665", "title": "Trial of a bacterial screening system for rapid detection of mutagens and carcinogens.", "content": "Trial of a bacterial screening system for rapid detection of mutagens and carcinogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365665"}
{"pmid": "4365666", "title": "Neurotoxicity of commonly used antineoplastic agents (second of two parts).", "content": "Neurotoxicity of commonly used antineoplastic agents (second of two parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365666"}
{"pmid": "4365667", "title": "Cytomegalovirus in semen. Persistence and demonstration in extracellular fluids.", "content": "Cytomegalovirus in semen. Persistence and demonstration in extracellular fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365667"}
{"pmid": "4365668", "title": "Letter: Implications of cyclic adenosine 3',5'-monophosphate in chronic renal failure.", "content": "Letter: Implications of cyclic adenosine 3',5'-monophosphate in chronic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365668"}
{"pmid": "4365670", "title": "Pneumonia in an intensive care unit. A 30-month experience.", "content": "Pneumonia in an intensive care unit. A 30-month experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365670"}
{"pmid": "4365669", "title": "Esophageal varices. Development secondary to primary and metastatic liver tumors.", "content": "Esophageal varices. Development secondary to primary and metastatic liver tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365669"}
{"pmid": "4365671", "title": "Letter: Gentamicin-resistant escherichia coli.", "content": "Letter: Gentamicin-resistant escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365671"}
{"pmid": "4365672", "title": "Subcellular localization of staphylococcal enterotoxin B in rabbit kidney.", "content": "Subcellular localization of staphylococcal enterotoxin B in rabbit kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365672"}
{"pmid": "4365673", "title": "Physicochemical properties of plasma renin substrate in normal, binephrectomized, and estrogen-treated rats.", "content": "Physicochemical properties of plasma renin substrate in normal, binephrectomized, and estrogen-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365673"}
{"pmid": "4365674", "title": "Effect of cyclic AMP, caffeine and theophylline on differentiation of lens epithelial cells.", "content": "Effect of cyclic AMP, caffeine and theophylline on differentiation of lens epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365674"}
{"pmid": "4365675", "title": "Some observations on spontaneously occurring tumours of the central nervous system of Sprague-Dawley derived rats.", "content": "Some observations on spontaneously occurring tumours of the central nervous system of Sprague-Dawley derived rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365675"}
{"pmid": "4365676", "title": "Pressor substances in the posthemodialysis dialysates of patients with toxemia of pregnancy.", "content": "Pressor substances in the posthemodialysis dialysates of patients with toxemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365676"}
{"pmid": "4365677", "title": "Rous sarcoma virus-transformed hamster tumor cells resistant to 5-bromodeoxyuridine.", "content": "Rous sarcoma virus-transformed hamster tumor cells resistant to 5-bromodeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365677"}
{"pmid": "4365678", "title": "Relationship between hydration and proton nuclear magnetic resonance relaxation times in tissues of tumor-bearing and non-tumor-bearing mice: implications for cancer detection.", "content": "Relationship between hydration and proton nuclear magnetic resonance relaxation times in tissues of tumor-bearing and non-tumor-bearing mice: implications for cancer detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365678"}
{"pmid": "4365679", "title": "Adult and embryonic gecko cells in vitro: growth characteristics, infection by rabies, sindbis and polyoma viruses, and transformation by SV40.", "content": "Adult and embryonic gecko cells in vitro: growth characteristics, infection by rabies, sindbis and polyoma viruses, and transformation by SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365679"}
{"pmid": "4365680", "title": "Structure-function relationships in phosphoinositides.", "content": "Structure-function relationships in phosphoinositides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365680"}
{"pmid": "4365683", "title": "Biochemical changes in cottonseed during germination.", "content": "Biochemical changes in cottonseed during germination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365683"}
{"pmid": "4365681", "title": "Extraction and production of renin and angiotensin II across several vascular beds in dogs.", "content": "Extraction and production of renin and angiotensin II across several vascular beds in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365681"}
{"pmid": "4365684", "title": "Vestibulospinal effects on hindlimb motoneurons of the frog.", "content": "Vestibulospinal effects on hindlimb motoneurons of the frog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365684"}
{"pmid": "4365685", "title": "Hormonally enhanced proliferation of human breast cancer in organ culture. An in vitro system for assessment of specific hormonal response.", "content": "Hormonally enhanced proliferation of human breast cancer in organ culture. An in vitro system for assessment of specific hormonal response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365685"}
{"pmid": "4365686", "title": "Radiologic assessment of the facial nerve.", "content": "Radiologic assessment of the facial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365686"}
{"pmid": "4365687", "title": "Dibutyryl cyclic 3':5'-adenosine monphosphate in hypopituitarism and Silver-Russell syndrome.", "content": "Dibutyryl cyclic 3':5'-adenosine monphosphate in hypopituitarism and Silver-Russell syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365687"}
{"pmid": "4365693", "title": "Laboratory recognition of coronary artery disease (with a review of the surgical treatment).", "content": "Laboratory recognition of coronary artery disease (with a review of the surgical treatment).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365693"}
{"pmid": "4365692", "title": "Radioimmunoassays.", "content": "Radioimmunoassays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365692"}
{"pmid": "4365696", "title": "Exercise after myocardial infarction.", "content": "Exercise after myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365696"}
{"pmid": "4365697", "title": "Hypothesis: hypothalamic dysfunction and lipoatrophic diabetes.", "content": "Hypothesis: hypothalamic dysfunction and lipoatrophic diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365697"}
{"pmid": "4365699", "title": "Avian tumor virus RNA: a comparison of three sarcoma viruses and their transformation-defective derivatives by oligonucleotide fingerprinting and DNA-RNA hybridization.", "content": "Avian tumor virus RNA: a comparison of three sarcoma viruses and their transformation-defective derivatives by oligonucleotide fingerprinting and DNA-RNA hybridization. Earlier electrophoretic analyses have shown that the 60-70S RNA of avian sarcoma viruses contains a characteristic subunit, termed class a subunit, which has a lower electrophoretic mobility than class b subunit found in transformation-defective derivatives of sarcoma viruses and in avian leukosis viruses. We have compared the RNAs of three nondefective avian sarcoma viruses, B77 and Prague and Schmidt-Ruppin strains of Rous sarcoma virus, with those of their transformation-defective (td) derivatives, td B77, td PR-C, and td SR-A, respectively, to determine the chemical basis for the difference between class a and b subunits. It was found by \"fingerprinting\" that (1) all (about 20-25) large T1 RNase-resistant oligonucleotides present in class b subunits of transformation-defective viruses have homologous counterparts in the class a subunits of corresponding nondefective sarcoma viruses and that (2) class a subunits contain a few (one or two) additional oligonucleotides that are not present in class b. By contrast the oligonucleotide fingerprints of avian tumor viruses of different strains and subgroups were very different.Cross hybridization of classes a and b RNA of sarcoma virus B77 with DNA transcribed from a corresponding transformation-defective virus td B77 showed that the two RNAs share at least 60% and differ by about 10% of their sequences. It is suggested that the structural relationship of class a and b subunits of corresponding viruses may be expressed as a = b + x, and that all the oligonucleotides present only in RNAs of sarcoma viruses but not in transformation-defective viruses of the corresponding strains are part of sequence(s) x. The possibility that x represents genetic information directly or indirectly involved in transformation of fibroblasts is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365699"}
{"pmid": "4365700", "title": "Growth-and density-dependent inhibition of deoxyglucose transport in Balb 3T3 cells and its absence in cells transformed by murine sarcoma virus.", "content": "Growth-and density-dependent inhibition of deoxyglucose transport in Balb 3T3 cells and its absence in cells transformed by murine sarcoma virus. The earliest measurable parameter that shows density-dependent inhibition is the uptake of [(3)H]deoxyglucose by Balb 3T3 cells. The rate decreases even during the exponential phase of growth and reaches a minimum, about 8- to 10-times lower than maximum, as the culture approaches the saturation density. Cells transformed by murine sarcoma virus fail to show either growth-dependent or density-dependent inhibition of deoxyglucose uptake. Treatment with dibutyryl cyclic AMP in the presence of theophylline results in premature cessation of growth and in an arrest in the decline of deoxyglucose transport. Culture in serum-deficient medium also produces rapid inhibition of growth at low cell density, but these cultures exhibit a markedly decreased rate of deoxyglucose uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365700"}
{"pmid": "4365702", "title": "Effect of ADP-induced shape change on incorporation of 32P into platelet phosphatidic acid and mono-, di- and triphosphatidyl inositol.", "content": "Effect of ADP-induced shape change on incorporation of 32P into platelet phosphatidic acid and mono-, di- and triphosphatidyl inositol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365702"}
{"pmid": "4365701", "title": "Guanosine 3':5'-cyclic monophosphate and the action of insulin and acetylcholine.", "content": "Guanosine 3':5'-cyclic monophosphate and the action of insulin and acetylcholine. Low concentrations of insulin (120 muunits/ml) and of carbamylcholine (1 muM) increase cyclic GMP content in isolated fat cells by 350%. The maximal amount of cyclic GMP, achieved within 2 min after addition of insulin or carbamylcholine, falls rapidly for insulin and much more slowly for carbamylcholine. 10 pM Acetylcholine can also augment the content of fat-cell cyclic GMP, but by 5 min (37 degrees ) the amount falls to that of unstimulated cells. Atropine abolishes the effects of carbamylcholine and acetylcholine but does not modify that of insulin, indicating that the ability of insulin to regulate cyclic GMP levels is not mediated by cholinergic receptors. Insulin and carbamylcholine increase the concentration of cyclic GMP in rat-liver slices by 400%; the effects of both agents occur rapidly and are relatively transient. Insulin does not alter cyclic GMP concentrations in purified human peripheral lymphocytes or in rat-spleen lymphocytes, cells which possess few insulin receptors and which are insensitive to the metabolic effects of the hormone. Carbamylcholine, however, causes a substantial increase in the cyclic GMP content of these lymphocytes. The data support the view that close and reciprocal relationships may exist between the concentrations and actions of cyclic AMP and cyclic GMP, as well as between the enzymes responsible for biosynthesis and degradation of these nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365701"}
{"pmid": "4365698", "title": "Toxic proteins produced by Clostridium botulinum.", "content": "Toxic proteins produced by Clostridium botulinum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365698"}
{"pmid": "4365705", "title": "Letter: Status report: feline leukemia.", "content": "Letter: Status report: feline leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365705"}
{"pmid": "4365709", "title": "The biogenesis of mitochondria in Neurospora crassa: ultrastructural changes induced by nutrients.", "content": "The biogenesis of mitochondria in Neurospora crassa: ultrastructural changes induced by nutrients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365709"}
{"pmid": "4365711", "title": "Physical compatibility and chemical stability of cephapirin sodium in combination with antibiotics and large-volume parenteral solutions. I.", "content": "Physical compatibility and chemical stability of cephapirin sodium in combination with antibiotics and large-volume parenteral solutions. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365711"}
{"pmid": "4365712", "title": "An ultrastructural study of the first cleavage of Xenopus embryos.", "content": "An ultrastructural study of the first cleavage of Xenopus embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365712"}
{"pmid": "4365710", "title": "Conjunctivitis. Differential diagnosis and treatment.", "content": "Conjunctivitis. Differential diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365710"}
{"pmid": "4365714", "title": "Invisible glomus tumor.", "content": "Invisible glomus tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365714"}
{"pmid": "4365713", "title": "Homology between human breast tumour RNA and mouse mammary tumour virus genome.", "content": "Homology between human breast tumour RNA and mouse mammary tumour virus genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365713"}
{"pmid": "4365716", "title": "Tumours of the nervous system in the African in Eritrea (Ethiopia).", "content": "Tumours of the nervous system in the African in Eritrea (Ethiopia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365716"}
{"pmid": "4365715", "title": "Fine structure and cytochemistry of testicular cells in men treated with testosterone propionate.", "content": "Fine structure and cytochemistry of testicular cells in men treated with testosterone propionate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365715"}
{"pmid": "4365717", "title": "Serological characterization of the three major proteins of vesicular stomatitis virus.", "content": "Serological characterization of the three major proteins of vesicular stomatitis virus. The three major proteins of vesicular stomatitis virus-Indiana, glycoprotein (G), nucleoprotein (N), and membrane protein (M), were isolated and characterized by means of specific monocomponent antisera. G, N, and M proteins are distinct, nonrelated antigens with specific serological properties. The G protein is the only antigen inducing the formation of virus-neutralizing antibodies and was shown to confer immunity to mice. Specific complement-fixing and precipitating activity was demonstrated for each of the three antisera. The future use of isolated rhabdovirus components and of monospecific antisera is considered for therapeutic and diagnostic purposes as well as for virus strain differentiation and classification work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365717"}
{"pmid": "4365719", "title": "Presence in leukemic cells of avian myeloblastosis virus-specific DNA sequences absent in normal chicken cells.", "content": "Presence in leukemic cells of avian myeloblastosis virus-specific DNA sequences absent in normal chicken cells. (3)H-labeled 35S RNA from purified avian myeloblastosis virus (AMV) was exhaustively hybridized with an excess of normal chicken DNA to remove all viral RNA sequences which are complementary to DNA from uninfected cells. The [(3)H]RNA which failed to hybridize was isolated by hydroxylapatite column chromatography which separates DNA-RNA hybrids from single-stranded [(3)H]RNA. The residual RNA hybridized to leukemic chicken DNA but did not rehybridize with normal chicken DNA. This demonstrates conclusively that DNA from AMV-induced leukemic cells contain viral-specific sequences which are absent in DNA from normal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365719"}
{"pmid": "4365721", "title": "Colitis in mice with a high incidence of rectal prolapse.", "content": "Colitis in mice with a high incidence of rectal prolapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365721"}
{"pmid": "4365718", "title": "Inhibition of herpes simplex virus type 2 replication by thymidine.", "content": "Inhibition of herpes simplex virus type 2 replication by thymidine. Replication of herpes simplex virus type 2 (HSV-2) was impeded in KB cells which were blocked in their capacity to synthesize DNA by 2 mM thymidine (TdR). The degree of inhibition was dependent upon the concentration of TdR. In marked contrast, HSV-1 is able to replicate under these conditions. The failure of HSV-2 to replicate is probably due to the inhibition of viral DNA synthesis; there was a marked reduction in the rate of DNA synthesis as well as the total amount of HSV-2 DNA made in the presence of 2 mM TdR. We postulated that the effect of TdR on viral replication occurs at the level of ribonucleotide reductase in a manner similar to KB cells. However, unlike KB cells, an altered ribonucleotide reductase activity, highly resistant to thymidine triphosphate inhibition, was found in extracts of HSV-2-infected KB cells. This activity was present in HSV-2-infected cells incubated in the presence or absence of TdR. Ribonucleotide reductase activity in extracts of HSV-1-infected KB cells showed a similar resistance to thymidine triphosphate inhibition. These results suggest that the effect of TdR on HSV-2 replication occurs at a stage of DNA synthesis other than reduction of cytidine nucleotides to deoxycytidine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365718"}
{"pmid": "4365722", "title": "Quantitative studies on the migration and development of Taenia pisiformis larvae in laboratory rabbits.", "content": "Quantitative studies on the migration and development of Taenia pisiformis larvae in laboratory rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365722"}
{"pmid": "4365723", "title": "Bacterial diseases of bats: a review.", "content": "Bacterial diseases of bats: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365723"}
{"pmid": "4365724", "title": "Heart rate in caged rhesus monkeys (Macaca mulatta).", "content": "Heart rate in caged rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365724"}
{"pmid": "4365725", "title": "A new technical approach for the study of endometrial regeneration in the rabbit.", "content": "A new technical approach for the study of endometrial regeneration in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365725"}
{"pmid": "4365726", "title": "Comparative aspects of mastocytosis in man and animals with report of a case in a baboon.", "content": "Comparative aspects of mastocytosis in man and animals with report of a case in a baboon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365726"}
{"pmid": "4365727", "title": "The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.", "content": "The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365727"}
{"pmid": "4365720", "title": "The changing seborrheic keratosis.", "content": "The changing seborrheic keratosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365720"}
{"pmid": "4365728", "title": "Interrelation of epithelial glycogen, cell proliferation and cellular migration with cyclic adenosine monophosphate in epithelial wound healing.", "content": "Interrelation of epithelial glycogen, cell proliferation and cellular migration with cyclic adenosine monophosphate in epithelial wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365728"}
{"pmid": "4365729", "title": "Hyporeactivity of tissue cultures.", "content": "Hyporeactivity of tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365729"}
{"pmid": "4365730", "title": "Radioimmunoassay of insulin by the double antibody method. Evaluation of the techique in practice.", "content": "Radioimmunoassay of insulin by the double antibody method. Evaluation of the techique in practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365730"}
{"pmid": "4365732", "title": "A new indigogenic method for the light and electron microscopic demonstration of 5'-nucleotide phosphodiesterases.", "content": "A new indigogenic method for the light and electron microscopic demonstration of 5'-nucleotide phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365732"}
{"pmid": "4365734", "title": "A mitochondrial iron protein with properties of a high-potential iron-sulfur protein.", "content": "A mitochondrial iron protein with properties of a high-potential iron-sulfur protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365734"}
{"pmid": "4365733", "title": "Histochemical demonstration of xanthine dehydrogenase in the tissues of the domestic fowl.", "content": "Histochemical demonstration of xanthine dehydrogenase in the tissues of the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365733"}
{"pmid": "4365735", "title": "Unsubstituted agarose as an affinity matrix for isolation of NAD-dependent alpha-glycerophosphate dehydrogenase from the trypanosomatid Crithidia fasciculata.", "content": "Unsubstituted agarose as an affinity matrix for isolation of NAD-dependent alpha-glycerophosphate dehydrogenase from the trypanosomatid Crithidia fasciculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365735"}
{"pmid": "4365736", "title": "Mobilization of iron from reticulocyte ghosts by cytoplasmic agents.", "content": "Mobilization of iron from reticulocyte ghosts by cytoplasmic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365736"}
{"pmid": "4365738", "title": "Kinetics of Woodward's Reagent K hydrolysis and reaction with staphylococcal nuclease.", "content": "Kinetics of Woodward's Reagent K hydrolysis and reaction with staphylococcal nuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365738"}
{"pmid": "4365737", "title": "Evaluation of mammography based upon correlation of specimen mammograms and histopathologic findings.", "content": "Evaluation of mammography based upon correlation of specimen mammograms and histopathologic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365737"}
{"pmid": "4365739", "title": "Yeast glycogen synthetase in the glucose 6-phosphate-dependent form. I. Purification and properties.", "content": "Yeast glycogen synthetase in the glucose 6-phosphate-dependent form. I. Purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365739"}
{"pmid": "4365740", "title": "Myosin in cultured fibroblasts.", "content": "Myosin in cultured fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365740"}
{"pmid": "4365741", "title": "The interaction of polypeptide components of human high density lipoprotein with sodium dodecyl sulfate.", "content": "The interaction of polypeptide components of human high density lipoprotein with sodium dodecyl sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365741"}
{"pmid": "4365742", "title": "Comparison of surface membranes isolated from cultured murine neuroblastoma cells in the differentiated or undifferentiated state.", "content": "Comparison of surface membranes isolated from cultured murine neuroblastoma cells in the differentiated or undifferentiated state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365742"}
{"pmid": "4365745", "title": "Childhood cancer: the national Wilm's tumor study. A progress report.", "content": "Childhood cancer: the national Wilm's tumor study. A progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365745"}
{"pmid": "4365744", "title": "Proceedings: Rhodopsin and light-sensitive kinase activity of retinal outer segments.", "content": "Proceedings: Rhodopsin and light-sensitive kinase activity of retinal outer segments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365744"}
{"pmid": "4365743", "title": "Epinephrine and adrenocorticotropic hormone-stimulated magnesium accumulation in adipocytes and their plasma membranes.", "content": "Epinephrine and adrenocorticotropic hormone-stimulated magnesium accumulation in adipocytes and their plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365743"}
{"pmid": "4365746", "title": "Immediate inactivation of T7 coliphage treated by monofunctional alkylating agents.", "content": "Immediate inactivation of T7 coliphage treated by monofunctional alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365746"}
{"pmid": "4365749", "title": "Rapid diagnostic techniques in clinical virology.", "content": "Rapid diagnostic techniques in clinical virology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365749"}
{"pmid": "4365748", "title": "The association of adenovirus infection with disease of the intestinal tract.", "content": "The association of adenovirus infection with disease of the intestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365748"}
{"pmid": "4365750", "title": "Immunoglobulins in virus disease.", "content": "Immunoglobulins in virus disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365750"}
{"pmid": "4365757", "title": "Immunofluorescence evidence for the distribution of cyclic AMP in cells and cell masses of the cellular slime molds.", "content": "Immunofluorescence evidence for the distribution of cyclic AMP in cells and cell masses of the cellular slime molds. With immunofluorescent techniques it has been possible to show that bound cyclic AMP is uniformly distributed in the nucleus and cytoplasm of a number of species of cellular slime molds. One species (which does not respond to cyclic AMP as an acrasin) is an exception and has its cyclic AMP concentrated in the nucleus during the feeding and aggregation stage. In cell masses of Dictyostelium discoideum that show early signs of differentiation the anterior, prestalk cells contain more cyclic AMP than the posterior, prespore cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365757"}
{"pmid": "4365758", "title": "Effects of epinephrine, adrenocorticotrophic hormone, and theophylline on adenosine 3', 5'-monophosphate phosphodiesterase activity in fat cells.", "content": "Effects of epinephrine, adrenocorticotrophic hormone, and theophylline on adenosine 3', 5'-monophosphate phosphodiesterase activity in fat cells. When rat fat cells were incubated with ACTH, epinephrine, or theophylline for 2 to 10 min, cyclic AMP phosphodiesterase (3':5'-cyclic-AMP 5'-nucleotidohydrolase, E.C. 3.1.4.17) activity (K(m) about 0.39 muM) in the 100,000 x g sediment fraction of homogenates was increased 35 to 50%. The effects of epinephrine and ACTH were concentration dependent and maximal increases were produced with concentrations similar to those that maximally stimulate lipolysis. Theophylline (0.5 mM) similarly increased phosphodiesterase activity but did not enhance the effects of maximally effective concentrations of the hormones. The changes in phosphodiesterase activity following addition of ACTH or theophylline paralleled changes in cell cyclic AMP content; both reached a maximum within 5 min and then declined, approaching basal levels after 20 or 30 min. The increased phosphodiesterase activity in cells incubated for 5 min with epinephrine reverted to basal levels within 2.5 min after the addition of propranolol. Our data are consistent with the view that there is a component of the fat-cell phosphodiesterase, perhaps localized in the plasma membrane, whose activity can be acutely modified by the concentration of its substrate, cyclic AMP. As previously reported (J. Biol. Chem.248, 7164-7170, 1973), exposure of fat cells to insulin increases the activity of a low K(m) phosphodiesterase also localized in the 100,000 x g sediment fraction of fat cell homogenates. In the presence of insulin, however, phosphodiesterase remained elevated for at least 40 min and there was no significant change in fat-cell cyclic AMP content. When phosphodiesterase activity was elevated and cyclic AMP content maintained at a high level by incubation of cells with ACTH plus theophylline, insulin produced a further increase in enzyme activity. Whether or not insulin and ACTH (or epinephrine or theophylline) affect the same phosphodiesterase, there seems little doubt that the underlying mechanisms are different.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365758"}
{"pmid": "4365759", "title": "Immune lysis of liposomes and erythrocyte ghosts loaded with spin label.", "content": "Immune lysis of liposomes and erythrocyte ghosts loaded with spin label. It is shown that the paramagnetic resonance of spin labels offers a convenient technique for monitoring the complement-mediated immune lysis of erythrocyte ghosts, and sensitized phospholipid liposomes. The ghosts or liposomes are loaded with a concentrated solution of a water-soluble, membrane-impermeable spin label, so that there is a strong exchange broadening of the paramagnetic resonance signal due to labels enclosed within the liposomes or ghosts. Complement-mediated lysis releases the labels into a dilute solution, where a relatively sharp and intense paramagnetic resonance signal is detected. AN UNANTICIPATED RESULT IS ALSO REPORTED: this is the augmentation of release of spin label from loaded ghosts sensitized with egg albumin, in the presence of antibody against egg albumin, complement, and egg albumin in solution, over and above the release in the absence of egg albumin in solution. Comparison with complement fixation suggests that the augmentation of lysis is effected by crosslinking of immune complexes with the cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365759"}
{"pmid": "4365761", "title": "Angiotensin-converting enzyme from rabbit pulmonary particles.", "content": "Angiotensin-converting enzyme from rabbit pulmonary particles. Angiotensin-converting enzyme has been solubilized from rabbit pulmonary particles and purified to homogeneity. The molecular weight of the native enzyme was estimated to be about 136,000 by glycerol gradient centrifugation, and a value of 140,000 was obtained for the reduced denatured protein by disc-gel electrophoresis in the presence of sodium dodecyl sulfate and 2-mercaptoethanol. The enzyme was found to be a glycoprotein with carbohydrate accounting for approximately 16% of its dry weight. The major sugar residues were identified as galactose, N-acetylglucosamine, and mannose, with smaller amounts of fucose and sialic acid. The homogeneous enzyme catalyzed the release of His-Leu from the COOH-terminus of angiotensin I and of Phe-Arg and Ser-Pro from that of bradykinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365761"}
{"pmid": "4365762", "title": "Interspecific recombination of mitochondrial DNA molecules in hybrid somatic cells.", "content": "Interspecific recombination of mitochondrial DNA molecules in hybrid somatic cells. The mitochondrial DNA (mtDNA) in rodent-human hybrid somatic cells was studied in strains that contain nucleotide sequences from both parental mtDNAs. A test for linkage of rodent to human mtDNA was devised on the basis of the density and sequence differences between these DNAs. When a mixture of rodent and human mtDNAs was banded in a CsCl gradient and each fraction hybridized with a mixture of complementary [(3)H]RNA transcribed from human mtDNA and complementary [(32)P]RNA transcribed from rodent mtDNA, each DNA was detected as a distinct and separate band at its expected density by specific hybridization with its complementary RNA. In some of the hybrid cell strains, the mtDNA sequences derived from the two species did not separate in the CsCl gradients. This result is interpreted as evidence for linkage between sequences from the two parental mtDNAs. While the exact nature of the linkage and the structure of the molecules containing both types of sequences are not known, the evidence supports the conclusion that the linkage is realized by a covalent bond. An event leading to the covalent bonding of these different sequences may be described as recombination. Among 18 hybrid cell strains examined, 13 contained large proportions of recombinant molecules. These molecules were found in both mouse-human and rat-human strains, and in strains containing more human or more rodent mtDNA sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365762"}
{"pmid": "4365760", "title": "Characterization and substrate specificity of a protein carboxymethylase in the pituitary gland.", "content": "Characterization and substrate specificity of a protein carboxymethylase in the pituitary gland. Protein carboxymethylase, an enzyme capable of methylating proteins and polypeptides, was purified from bovine pituitary. The anterior pituitary hormones, luteinizing hormone, follicle-stimulating hormone, adrenocorticotropic hormone, growth hormone, thyroid-stimulating hormone, and prolactin, were found to be substrates for this enzyme. The posterior pituitary hormones, oxytocin and vasopressin, did not serve as substrates. With luteinizing hormone as the substrate, protein carboxymethylase had a pH optimum near pH 5.5. A limiting K(m) of 1.47 muM for S-adenosyl-L-methionine was obtained with luteinizing hormone as the methyl acceptor. Possible roles of this enzyme in the posterior and anterior pituitary are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365760"}
{"pmid": "4365764", "title": "Cyclic-AMP-controlled oscillations in suspended Dictyostelium cells: their relation to morphogenetic cell interactions.", "content": "Cyclic-AMP-controlled oscillations in suspended Dictyostelium cells: their relation to morphogenetic cell interactions. Periodic spikes of decreased optical density were recorded in cell suspensions of Dictyostelium discoideum. Spike formation as well as changes in the redox state of cytochrome b are facultatively and independently coupled to an oscillating system which is under developmental control and presumably underlies signal transmission in aggregating cells. Cyclic AMP triggers a double response, the slow component resembling the spikes formed during spontaneous oscillations. The fast component shows characteristics of the chemotactic response to cyclic AMP. The receptor system is suggested to sense changes of cyclic AMP concentration in time. Cyclic AMP pulses interact with the oscillating system, resulting in phase shift or suppression of spike formation, and in the induction of oscillations in an early stage of development before the onset of spontaneous oscillations. Continuous flow application of cyclic AMP does not change frequency up to flow rates which extinguish oscillations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365764"}
{"pmid": "4365763", "title": "Estrogen-related increases in uterine guanosine 3':5'-cyclic momophosphate levels.", "content": "Estrogen-related increases in uterine guanosine 3':5'-cyclic momophosphate levels. Endogenous uterine cyclic GMP and cyclic AMP concentrations were monitored at each stage of the estrus cycle; cyclic GMP concentrations were found to be highest and cyclic AMP concentrations lowest during proestrus when plasma estrogen levels have been shown to be maximal. After administration of estradiol-17beta or diethylstilbestrol, the concentrations of uterine cyclic GMP in ovariectomized rats underwent a progressive and significant elevation and the levels of cyclic AMP declined significantly below control values when near maximal accumulation of tissue cyclic GMP was achieved. The increase in uterine cyclic GMP concentrations produced by estradiol benzoate administration was prevented when progesterone and the estrogen were co-administered. These results raise the possibility that an enhanced cellular accumulation of cyclic GMP may be involved in the expression of some of the actions of estrogen in uterine tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365763"}
{"pmid": "4365765", "title": "Simultaneous administration of dichlorvos anthelmintic and modified live virus vaccines to puppies.", "content": "Simultaneous administration of dichlorvos anthelmintic and modified live virus vaccines to puppies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365765"}
{"pmid": "4365768", "title": "A study of serum vitamin B12 in various peripheral neuropathies.", "content": "A study of serum vitamin B12 in various peripheral neuropathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365768"}
{"pmid": "4365772", "title": "Third F. Raymond Keating, Jr., Memorial Symposium--parathyroid hormone, calcitonin and vitamin D: clinical considerations. II. Vitamin D--1973.", "content": "Third F. Raymond Keating, Jr., Memorial Symposium--parathyroid hormone, calcitonin and vitamin D: clinical considerations. II. Vitamin D--1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365772"}
{"pmid": "4365773", "title": "Rickets and the pathogenesis of impaired tubular transport of phosphate and other solutes.", "content": "Rickets and the pathogenesis of impaired tubular transport of phosphate and other solutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365773"}
{"pmid": "4365774", "title": "The physiologic significance of plasma transport of vitamin D and metabolites.", "content": "The physiologic significance of plasma transport of vitamin D and metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365774"}
{"pmid": "4365775", "title": "Circulating 25-hydroxyvitamin D in man.", "content": "Circulating 25-hydroxyvitamin D in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365775"}
{"pmid": "4365776", "title": "Intrauterine infection and cord immunoglobulin M. 3. Serological analysis of infants with elevated cord serum immunoglobulin M.", "content": "Intrauterine infection and cord immunoglobulin M. 3. Serological analysis of infants with elevated cord serum immunoglobulin M. The presence of antibodies to rubella, cytomegalovirus and Toxoplasma gondii was determined at birth and at 6 months of age in a group of 147 infants with cord serum IgM levels >/= 19.0 mg/dl and in 92 control infants. Maternal syphilis serology was determined in both groups as well. No significant differences in the prevalence or levels of antibodies to these pathogens were found between the two groups which might have led to the diagnosis of unsuspected intrauterine infection. Persistence of antibodies to 6 months of age was similar in the two groups, indicating that this is not a useful index of intrauterine infection.ANALYSIS OF THE RESULTS YIELDED THE FOLLOWING DATA ON THE PREVALENCE OF ANTIBODIES TO THE PATHOGENS STUDIED: rubella virus, 90 and 75% seropositivity at birth and 6 months respectively; cytomegalovirus, 65 and 35%; and Toxoplasma gondii, 33% seropositivity at birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365776"}
{"pmid": "4365778", "title": "Transport of peroxidase in flounder kidney tubules studied by electron microscope histochemistry.", "content": "Transport of peroxidase in flounder kidney tubules studied by electron microscope histochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365778"}
{"pmid": "4365779", "title": "Sedative or tranquillizer? A comparison of the hypnotic effects of chlordiazepoxide and amylobarbitone sodium.", "content": "Sedative or tranquillizer? A comparison of the hypnotic effects of chlordiazepoxide and amylobarbitone sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365779"}
{"pmid": "4365780", "title": "Nuclear gene dosage effects on mitochondrial mass and DNA.", "content": "Nuclear gene dosage effects on mitochondrial mass and DNA. In order to assess the effect of nuclear gene dosage on the regulation of mitochondria we have studied serial sections of a set of isogenic haploid and diploid cells of Saccharomyces cerevisiae, growing exponentially in the absence of catabolite repression, and determined the amount of mitochondrial DNA per cell. Mitochondria accounted for 14% of the cytoplasmic and 12% of the total cellular volume in all cells examined regardless of their ploidy or their apparent stage in the cell cycle. The mean number of mitochondria per cell was 22 in the diploid and 10 in the haploids. The volume distribution appeared unimodal and identical in haploids and diploids. The mitochondrial DNA accounted for 12.6 +/- 1.2% and 13.5 +/- 1.3% of the total cellular DNA in the diploid and haploid populations, respectively. These values correspond to 3.6 x 10(-15) g, 2.2 x 10(9) daltons, or 44 genomes (50 x 10(6) daltons each) per haploid and twice that per diploid cell. On this basis, the average mitochondrion in these cells contains four mitochondrial genomes in both the haploid and the diploid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365780"}
{"pmid": "4365781", "title": "Lysosomal packaging in differentiating and degenerating anuran lateral motor column neurons.", "content": "Lysosomal packaging in differentiating and degenerating anuran lateral motor column neurons. The role of the Golgi apparatus and the Golgi-endoplasmic reticulum-lysosome complex (GERL) in the genesis of lysosomes was examined in differentiating and degenerating motor neurons of anuran larvae. Acid phosphatase, aryl sulfatase, and thiolacetic acid esterase were utilized as marker enzymes for the lysosomal system, while nucleoside diphosphatase and thiamine pyrophosphatase labeled the inner saccule(s) of the Golgi apparatus. Reduced osmium tetroxide was routinely deposited in the outer Golgi saccule regardless of the state of neuronal maturation. In all young neurons, the disposition of acid hydrolase reaction product paralleled the formation of GERL, with no lytic activity in the Golgi apparatus per se. Hypertrophy of the Golgi apparatus and GERL was observed in the early phases of degeneration, and both organelles apparently exhibit extensive hydrolytic activity. Dense bodies, autophagic vacuoles, and primary lysosomes were found arising from GERL, while the Golgi apparatus may produce primary lysosomal granules during regression. On the other hand, in differentiating neurons, hydrolytic activity was restricted to GERL and an occasional dense body and autophagic vacuole. These studies illustrate a parallelism between the development of GERL and genesis of primary and secondary lysosomes during neuronal cytodifferentiation, and implicate GERL and possibly the Golgi apparatus in lysosomal packaging in degenerating neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365781"}
{"pmid": "4365787", "title": "Quinoline derivatives as antiallergy agents.", "content": "Quinoline derivatives as antiallergy agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365787"}
{"pmid": "4365788", "title": "Thymidine 5' variants as inhibitors of thymidylate kinase.", "content": "Thymidine 5' variants as inhibitors of thymidylate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365788"}
{"pmid": "4365789", "title": "Morphology of mesenchymal elements of normal artery, fatty streaks, and plaques.", "content": "Morphology of mesenchymal elements of normal artery, fatty streaks, and plaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365789"}
{"pmid": "4365790", "title": "Studies of primate arterial smooth muscle cells in relation to atherosclerosis.", "content": "Studies of primate arterial smooth muscle cells in relation to atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365790"}
{"pmid": "4365791", "title": "Changes in plasma levels of estrone sulfate and estrone in the pregnant ewe around parturition.", "content": "Changes in plasma levels of estrone sulfate and estrone in the pregnant ewe around parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365791"}
{"pmid": "4365792", "title": "Fatal herpes hepatitis associated with pemphigus vulgaris and steroids in an adult.", "content": "Fatal herpes hepatitis associated with pemphigus vulgaris and steroids in an adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365792"}
{"pmid": "4365798", "title": "Dugbe virus: a tick-borne arbovirus from Nigeria.", "content": "Dugbe virus: a tick-borne arbovirus from Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365798"}
{"pmid": "4365794", "title": "Thiamine diphosphate content of liver mitochondria of the pregnant and developing rat.", "content": "Thiamine diphosphate content of liver mitochondria of the pregnant and developing rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365794"}
{"pmid": "4365799", "title": "Partial separation of Sendai virus-fused lymphocytes by velocity sedimentation.", "content": "Partial separation of Sendai virus-fused lymphocytes by velocity sedimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365799"}
{"pmid": "4365803", "title": "Intracellular concentration of inorganic pyrophosphate in the cells of Escherichia coli: a method for its determination.", "content": "Intracellular concentration of inorganic pyrophosphate in the cells of Escherichia coli: a method for its determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365803"}
{"pmid": "4365801", "title": "Riboflavin deficiency and galactose metabolism in human subjects.", "content": "Riboflavin deficiency and galactose metabolism in human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365801"}
{"pmid": "4365804", "title": "A microassay for guanosine 3',5'-monophosphate phosphodiesterase activity.", "content": "A microassay for guanosine 3',5'-monophosphate phosphodiesterase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365804"}
{"pmid": "4365802", "title": "Microsomal Na+-stimulated NADH-cytochrome c reductase: could it be involved in sodium transport?", "content": "Microsomal Na+-stimulated NADH-cytochrome c reductase: could it be involved in sodium transport?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365802"}
{"pmid": "4365805", "title": "Assay of cyclic AMP by an isotope dilution test with binding protein.", "content": "Assay of cyclic AMP by an isotope dilution test with binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365805"}
{"pmid": "4365806", "title": "Coprecipitation of ATP with potassium perchlorate: the effect of the firefly enzyme assay of ATP in tissue and blood.", "content": "Coprecipitation of ATP with potassium perchlorate: the effect of the firefly enzyme assay of ATP in tissue and blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365806"}
{"pmid": "4365807", "title": "Separation and automated analysis of phosphorylated metabolic intermediates.", "content": "Separation and automated analysis of phosphorylated metabolic intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365807"}
{"pmid": "4365808", "title": "Langerhans cells in a bronchiolar-alveolar tumour of lung.", "content": "Langerhans cells in a bronchiolar-alveolar tumour of lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365808"}
{"pmid": "4365809", "title": "A statistical analysis of the release of acetylcholine at newly formed synapses in striated muscle.", "content": "A statistical analysis of the release of acetylcholine at newly formed synapses in striated muscle. 1. A statistical analysis has been made of the changes in the binomial parameters n and p during transmitter release from motor-nerve terminals when synapses are forming in either regenerating or reinnervated mammalian muscle.2. The amplitude-frequency distribution of e.p.p.s evoked by a single impulse was well predicted by binomial statistics at all junctions analysed allowing values of n and p to be determined. At most of these junctions, p > 0.5 and Poisson statistics did not predict the observed distributions at all.3. During the changes in quantal content which occur during short trains of impulses or during continual stimulation over minutes, no significant change in p was detected. Changes in quantal content of the e.p.p. were therefore determined by n.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365809"}
{"pmid": "4365811", "title": "Sulfhydryl group reactivity of D-galactose dehydrogenases from Pseudomonas saccharophila.", "content": "Sulfhydryl group reactivity of D-galactose dehydrogenases from Pseudomonas saccharophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365811"}
{"pmid": "4365812", "title": "28-S RNA from Xenopus laevis contains a sequence of three adjacent 2'-O-methylations.", "content": "28-S RNA from Xenopus laevis contains a sequence of three adjacent 2'-O-methylations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365812"}
{"pmid": "4365814", "title": "Aspiration biopsy cytology. I. Cytology of supradiaphragmatic organs. 8 Lungs.", "content": "Aspiration biopsy cytology. I. Cytology of supradiaphragmatic organs. 8 Lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365814"}
{"pmid": "4365813", "title": "Characterization of blood-group-H-active ceramide tetrasaccharide from hog-stomach mucosa.", "content": "Characterization of blood-group-H-active ceramide tetrasaccharide from hog-stomach mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365813"}
{"pmid": "4365816", "title": "Proceedings: Plasma levels of amino acids and glucagon in patients with pancreatic glucagonomas.", "content": "Proceedings: Plasma levels of amino acids and glucagon in patients with pancreatic glucagonomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365816"}
{"pmid": "4365818", "title": "Editorial: Vitamin D, the kidney and calcium homeostasis.", "content": "Editorial: Vitamin D, the kidney and calcium homeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365818"}
{"pmid": "4365817", "title": "Fine-structural observations on the gill filaments of the fresh-water crayfish, Astacus pallipes Lereboullet.", "content": "Fine-structural observations on the gill filaments of the fresh-water crayfish, Astacus pallipes Lereboullet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365817"}
{"pmid": "4365819", "title": "The effect of exogenous angiotensin on superficial and deep glomeruli in the rat kidney.", "content": "The effect of exogenous angiotensin on superficial and deep glomeruli in the rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365819"}
{"pmid": "4365820", "title": "An evaluation of the contribution of cholinergic mechanism to thirst.", "content": "An evaluation of the contribution of cholinergic mechanism to thirst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365820"}
{"pmid": "4365821", "title": "Centrally mediated effects of angiotensin II in the unanesthetized rat.", "content": "Centrally mediated effects of angiotensin II in the unanesthetized rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365821"}
{"pmid": "4365831", "title": "Studies on Coccidioides immitis. XVII: Morphology of the parasite in relationship with the host immunoallergic condition in the experimental infection of the guinea-pig.", "content": "Studies on Coccidioides immitis. XVII: Morphology of the parasite in relationship with the host immunoallergic condition in the experimental infection of the guinea-pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365831"}
{"pmid": "4365832", "title": "Occurrence of atypical lymphocytes following intravenous injection of Candida albicans in mice.", "content": "Occurrence of atypical lymphocytes following intravenous injection of Candida albicans in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365832"}
{"pmid": "4365833", "title": "Comparative treatment of hyperlipoproteinaemias in chimpanzees.", "content": "Comparative treatment of hyperlipoproteinaemias in chimpanzees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365833"}
{"pmid": "4365836", "title": "Glycosylation of beta-lipoprotein and the possible role of choline derivatives.", "content": "Glycosylation of beta-lipoprotein and the possible role of choline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365836"}
{"pmid": "4365838", "title": "Enzymatic dehydrogenation of testosterone coupled to pyruvate reduction in a two-phase system.", "content": "Enzymatic dehydrogenation of testosterone coupled to pyruvate reduction in a two-phase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365838"}
{"pmid": "4365837", "title": "Urinary excretion of cyclic AMP by cold-acclimated rats.", "content": "Urinary excretion of cyclic AMP by cold-acclimated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365837"}
{"pmid": "4365839", "title": "Nucleophilic addition at the photoexcited flavin cation: synthesis and properties of 6- and 9-hydroxy-flavocoenzyme chromophores.", "content": "Nucleophilic addition at the photoexcited flavin cation: synthesis and properties of 6- and 9-hydroxy-flavocoenzyme chromophores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365839"}
{"pmid": "4365840", "title": "Identification and properties of new flavins in electron-transferring flavoprotein from Peptostreptococcus elsdenii and pig-liver glycolate oxidase.", "content": "Identification and properties of new flavins in electron-transferring flavoprotein from Peptostreptococcus elsdenii and pig-liver glycolate oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365840"}
{"pmid": "4365841", "title": "Regulation of myocardial contraction.", "content": "Regulation of myocardial contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365841"}
{"pmid": "4365842", "title": "Free fatty acids and the ischaemic myocardium.", "content": "Free fatty acids and the ischaemic myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365842"}
{"pmid": "4365844", "title": "Lymphocytes in infectious mononucleosis. Properties of atypical cells and origin on the lymphoblastoid lines.", "content": "Lymphocytes in infectious mononucleosis. Properties of atypical cells and origin on the lymphoblastoid lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365844"}
{"pmid": "4365843", "title": "Regulatory role of adenyl cyclase and cyclic AMP.", "content": "Regulatory role of adenyl cyclase and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365843"}
{"pmid": "4365846", "title": "Urea-cycle enzymes in normal liver and in patients with alcoholic hepatitis.", "content": "Urea-cycle enzymes in normal liver and in patients with alcoholic hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365846"}
{"pmid": "4365848", "title": "Effect of onion ingestion on serum triglyceride, betalipoprotein-cholesterol and phospholipids in alimentary lipaemia.", "content": "Effect of onion ingestion on serum triglyceride, betalipoprotein-cholesterol and phospholipids in alimentary lipaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365848"}
{"pmid": "4365851", "title": "Coeliac disease. Electron microscopy of jejunal mucosa.", "content": "Coeliac disease. Electron microscopy of jejunal mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365851"}
{"pmid": "4365856", "title": "Cytomegalovirus infection after lumbosacral fusion. A case report.", "content": "Cytomegalovirus infection after lumbosacral fusion. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365856"}
{"pmid": "4365859", "title": "Editorial: Sex and alcohol.", "content": "Editorial: Sex and alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365859"}
{"pmid": "4365852", "title": "Influence of prostaglandin E1 on cyclic 3',5'-AMP levels and glycosaminoglycan secretion of fibroblasts cultured in vitro.", "content": "Influence of prostaglandin E1 on cyclic 3',5'-AMP levels and glycosaminoglycan secretion of fibroblasts cultured in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365852"}
{"pmid": "4365855", "title": "Studies on human cytomegalovirus strain variations by membrane-fluorescence.", "content": "Studies on human cytomegalovirus strain variations by membrane-fluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365855"}
{"pmid": "4365860", "title": "Astrocytosis without globules in infant cerebral white matter. An epidemiologic study.", "content": "Astrocytosis without globules in infant cerebral white matter. An epidemiologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365860"}
{"pmid": "4365862", "title": "Vitreoretinal juncture--simple epiretinal membranes.", "content": "Vitreoretinal juncture--simple epiretinal membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365862"}
{"pmid": "4365863", "title": "Effect of dipyridamole on retinal embolism associated with cardiopulmonary bypass surgery in the dog.", "content": "Effect of dipyridamole on retinal embolism associated with cardiopulmonary bypass surgery in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365863"}
{"pmid": "4365865", "title": "Serum prolactin levels during ovulatory menstrual cycle and menstrual disorders in women.", "content": "Serum prolactin levels during ovulatory menstrual cycle and menstrual disorders in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365865"}
{"pmid": "4365864", "title": "Rubella and cytomegalovirus. Current concepts of congenital and acquired infection.", "content": "Rubella and cytomegalovirus. Current concepts of congenital and acquired infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365864"}
{"pmid": "4365853", "title": "Influence of antiphlogistic drugs on prostaglandin E1 stimulated cyclic 3',5'-AMP levels and glycosaminoglycan synthesis in fibroblast tissue cultures.", "content": "Influence of antiphlogistic drugs on prostaglandin E1 stimulated cyclic 3',5'-AMP levels and glycosaminoglycan synthesis in fibroblast tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365853"}
{"pmid": "4365867", "title": "Adynamic ileus, its pathogenesis and treatment.", "content": "Adynamic ileus, its pathogenesis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365867"}
{"pmid": "4365868", "title": "Plasma renin and angiotensin I converting enzyme activity in anaphylactic shock.", "content": "Plasma renin and angiotensin I converting enzyme activity in anaphylactic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365868"}
{"pmid": "4365854", "title": "Effects of prostaglandin synthesis inhibitors on angiotensin tachyphylaxis in the isolated coeliac and mesenteric arteries of the rabbit.", "content": "Effects of prostaglandin synthesis inhibitors on angiotensin tachyphylaxis in the isolated coeliac and mesenteric arteries of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365854"}
{"pmid": "4365866", "title": "A human papovavirus (B.K.), biological properties and seroepidemiology.", "content": "A human papovavirus (B.K.), biological properties and seroepidemiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365866"}
{"pmid": "4365871", "title": "Abnormal reflexes in the \"stiff-man\" syndrome.", "content": "Abnormal reflexes in the \"stiff-man\" syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365871"}
{"pmid": "4365873", "title": "A roentgenologic study of epiphyseal union around elbow, wrist and knee joints and the pelvis in boys and girls of Uttar Pradesh.", "content": "A roentgenologic study of epiphyseal union around elbow, wrist and knee joints and the pelvis in boys and girls of Uttar Pradesh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365873"}
{"pmid": "4365879", "title": "Guanidine inhibition of poliovirus growth. Partial elimination by protease antagonists and low temperature.", "content": "Guanidine inhibition of poliovirus growth. Partial elimination by protease antagonists and low temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365879"}
{"pmid": "4365880", "title": "Studies on beta-galactosidase activity in Vibrio El Tor.", "content": "Studies on beta-galactosidase activity in Vibrio El Tor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365880"}
{"pmid": "4365884", "title": "Biochemical studies on sulfate-ruducing bacteria. 8. Sulfite reductase from Desulfovibrio vulgaris--mechanism of trithionate, thiosulfate, and sulfide formation and enzymatic properties.", "content": "Biochemical studies on sulfate-ruducing bacteria. 8. Sulfite reductase from Desulfovibrio vulgaris--mechanism of trithionate, thiosulfate, and sulfide formation and enzymatic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365884"}
{"pmid": "4365886", "title": "The response of adipose tissue to lipid mobilizing hormones in postnatally under- and overnourished rats.", "content": "The response of adipose tissue to lipid mobilizing hormones in postnatally under- and overnourished rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365886"}
{"pmid": "4365885", "title": "The activity of adenylate cyclase, phosphodiesterase and protein kinase in the adenohypophyses of rats treated by chronic administration of estrogens and acute application of thyroxine in vivo.", "content": "The activity of adenylate cyclase, phosphodiesterase and protein kinase in the adenohypophyses of rats treated by chronic administration of estrogens and acute application of thyroxine in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365885"}
{"pmid": "4365887", "title": "Two types of insulin receptors mediating opposite effects on cyclic-amp in fat cells of the rat.", "content": "Two types of insulin receptors mediating opposite effects on cyclic-amp in fat cells of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365887"}
{"pmid": "4365889", "title": "Effect of insulin on the phosphorylation of adipose tissue protein.", "content": "Effect of insulin on the phosphorylation of adipose tissue protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365889"}
{"pmid": "4365888", "title": "Gastric HCO3-stimulated ATPase: evidence against its microsomal localization in rat fundus mucosa.", "content": "Gastric HCO3-stimulated ATPase: evidence against its microsomal localization in rat fundus mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365888"}
{"pmid": "4365890", "title": "Testosterone-estradiol-binding globulin of human plasma: denaturation and protection.", "content": "Testosterone-estradiol-binding globulin of human plasma: denaturation and protection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365890"}
{"pmid": "4365891", "title": "Purification of Clostridium perfringens phospholipase C (alpha-toxin) by affinity chromatography on agarose-linked egg-yolk lipoprotein.", "content": "Purification of Clostridium perfringens phospholipase C (alpha-toxin) by affinity chromatography on agarose-linked egg-yolk lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365891"}
{"pmid": "4365892", "title": "Synthetic analogs of the active sites of iron-sulfur proteins. 8. Some electronic properties of (Fe4S4(SR)4)3-, analogs of reduced bacterial ferredoxins.", "content": "Synthetic analogs of the active sites of iron-sulfur proteins. 8. Some electronic properties of (Fe4S4(SR)4)3-, analogs of reduced bacterial ferredoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365892"}
{"pmid": "4365893", "title": "A possible mechanism for the stimulation of Krebs cycle activity by ACTH in isolated rat adrenal cells.", "content": "A possible mechanism for the stimulation of Krebs cycle activity by ACTH in isolated rat adrenal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365893"}
{"pmid": "4365894", "title": "The influence of 2,3 diphosphoglycerate on the Bohr effect of sulfhemoglobin.", "content": "The influence of 2,3 diphosphoglycerate on the Bohr effect of sulfhemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365894"}
{"pmid": "4365895", "title": "Peptidase activity of carrier proteins used in radioimmunoassays.", "content": "Peptidase activity of carrier proteins used in radioimmunoassays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365895"}
{"pmid": "4365896", "title": "Pathomorphologic and histochemical changes in the liver during hemodilution.", "content": "Pathomorphologic and histochemical changes in the liver during hemodilution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365896"}
{"pmid": "4365897", "title": "Regulation of glycogen metabolism in acute uremic hearts.", "content": "Regulation of glycogen metabolism in acute uremic hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365897"}
{"pmid": "4365898", "title": "Catecholamine metabolism in health and disease.", "content": "Catecholamine metabolism in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365898"}
{"pmid": "4365899", "title": "Biochemical genetics of bacterial sporulation. V. Fine structure analysis of two sporulation mutants of B. subtilis derepressed for late functions.", "content": "Biochemical genetics of bacterial sporulation. V. Fine structure analysis of two sporulation mutants of B. subtilis derepressed for late functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365899"}
{"pmid": "4365900", "title": "Saponin adjuvants. 3. Isolation of a substance from Quillaja saponaria Molina with adjuvant activity in food-and-mouth disease vaccines.", "content": "Saponin adjuvants. 3. Isolation of a substance from Quillaja saponaria Molina with adjuvant activity in food-and-mouth disease vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365900"}
{"pmid": "4365901", "title": "The development of double-seeded and mixed cell culture systems for use in diagnostic virology.", "content": "The development of double-seeded and mixed cell culture systems for use in diagnostic virology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365901"}
{"pmid": "4365902", "title": "Replication and plaque formation of mouse hepatitis virus (MHV-2) in mouse cell line DBT culture.", "content": "Replication and plaque formation of mouse hepatitis virus (MHV-2) in mouse cell line DBT culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365902"}
{"pmid": "4365903", "title": "Effect of morphinization on in vitro incorporation of labelled precursors into adrenal protein and nucleic acids in rats.", "content": "Effect of morphinization on in vitro incorporation of labelled precursors into adrenal protein and nucleic acids in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365903"}
{"pmid": "4365904", "title": "Adrenergic mechanism in Tetrahymena. 3. Cyclic adenosine 3', 5'-monophosphate and cell proliferation.", "content": "Adrenergic mechanism in Tetrahymena. 3. Cyclic adenosine 3', 5'-monophosphate and cell proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365904"}
{"pmid": "4365906", "title": "Differentiation between early and late membrane antigen on human lymphoblastoid cell lines infected with Epstein-Barr virus. I. Immunofluorescence.", "content": "Differentiation between early and late membrane antigen on human lymphoblastoid cell lines infected with Epstein-Barr virus. I. Immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365906"}
{"pmid": "4365908", "title": "Latent infection and malignant lymphoma in marmosets (Callithrix jacchus) after infection with two oncogenic herpesviruses from primates.", "content": "Latent infection and malignant lymphoma in marmosets (Callithrix jacchus) after infection with two oncogenic herpesviruses from primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365908"}
{"pmid": "4365909", "title": "Pancreatic islet cell tumors in domestic animals. Data from 11 colleges of veterinary medicine in the United States and Canada.", "content": "Pancreatic islet cell tumors in domestic animals. Data from 11 colleges of veterinary medicine in the United States and Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365909"}
{"pmid": "4365907", "title": "Presence and transmission of mammary tumor virus and leukemia virus in the BALB-cfRIII mouse.", "content": "Presence and transmission of mammary tumor virus and leukemia virus in the BALB-cfRIII mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365907"}
{"pmid": "4365910", "title": "Variation in quantitative expression of Forssman antigen on virus-transformed hamster cells.", "content": "Variation in quantitative expression of Forssman antigen on virus-transformed hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365910"}
{"pmid": "4365912", "title": "Elevated cyclic AMP levels in human breast-cancer tissue.", "content": "Elevated cyclic AMP levels in human breast-cancer tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365912"}
{"pmid": "4365911", "title": "Zinc intake and growth of a transplanted hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene in rats.", "content": "Zinc intake and growth of a transplanted hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365911"}
{"pmid": "4365913", "title": "Acute cerebral infarction and hypotension: an ultrastructural study.", "content": "Acute cerebral infarction and hypotension: an ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365913"}
{"pmid": "4365914", "title": "The astrocyte response in experimental portal-systemic encephalopathy: an electron microscopic study.", "content": "The astrocyte response in experimental portal-systemic encephalopathy: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365914"}
{"pmid": "4365916", "title": "Electron-microscopic observations of scirrhous and mucin-producing carcinomas of the breast.", "content": "Electron-microscopic observations of scirrhous and mucin-producing carcinomas of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365916"}
{"pmid": "4365915", "title": "Gliomas containing bone and cartilage.", "content": "Gliomas containing bone and cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365915"}
{"pmid": "4365917", "title": "The nature of the circadian periodicity and suppressibility of immunoreactive ACTH levels in Addison's disease.", "content": "The nature of the circadian periodicity and suppressibility of immunoreactive ACTH levels in Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365917"}
{"pmid": "4365918", "title": "Cyclic adenosine 3',5'-monophosphate concentration in plasma, adipose tissue and skeletal muscle in normal subjects and in patients with hyper- and hypothyroidism.", "content": "Cyclic adenosine 3',5'-monophosphate concentration in plasma, adipose tissue and skeletal muscle in normal subjects and in patients with hyper- and hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365918"}
{"pmid": "4365919", "title": "Secretion of 16alpha-hydroxyprogesterone and other steroids by the adult human adrenal.", "content": "Secretion of 16alpha-hydroxyprogesterone and other steroids by the adult human adrenal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365919"}
{"pmid": "4365920", "title": "Regulation of aldosterone in the syndrome of inappropriate antidiuretic hormone secretion (SIADH).", "content": "Regulation of aldosterone in the syndrome of inappropriate antidiuretic hormone secretion (SIADH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365920"}
{"pmid": "4365921", "title": "Human adrenal tissue in vitro: steroidogenic properties.", "content": "Human adrenal tissue in vitro: steroidogenic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365921"}
{"pmid": "4365922", "title": "Cirrhosis and malignant hepatoma in alpha 1-antitrypsin deficiency.", "content": "Cirrhosis and malignant hepatoma in alpha 1-antitrypsin deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365922"}
{"pmid": "4365923", "title": "Respirable silica dust exposure of sandblasters and associated workers in steel fabrication yards.", "content": "Respirable silica dust exposure of sandblasters and associated workers in steel fabrication yards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365923"}
{"pmid": "4365924", "title": "Effects of cigarette smoke components on bronchial clearance in the donkey.", "content": "Effects of cigarette smoke components on bronchial clearance in the donkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365924"}
{"pmid": "4365925", "title": "Wilm's tumour.", "content": "Wilm's tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365925"}
{"pmid": "4365926", "title": "Intranuclear inclusions in the lead-poisoned cultured kidney cell.", "content": "Intranuclear inclusions in the lead-poisoned cultured kidney cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365926"}
{"pmid": "4365928", "title": "Cytophysiology and metabolism of pancreatic B-cell.", "content": "Cytophysiology and metabolism of pancreatic B-cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365928"}
{"pmid": "4365927", "title": "Plasma MSH and cortisol levels in 567 patients with special reference to brain trauma.", "content": "Plasma MSH and cortisol levels in 567 patients with special reference to brain trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365927"}
{"pmid": "4365930", "title": "Immediate effects of total visual deafferentation on single unit activity in the visual cortex of freely behaving cats. II. Rhythmic EEG bursts and PGO waves.", "content": "Immediate effects of total visual deafferentation on single unit activity in the visual cortex of freely behaving cats. II. Rhythmic EEG bursts and PGO waves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365930"}
{"pmid": "4365929", "title": "Immediate effects of total visual deafferentation on single unit activity in the visual cortex of freely behaving cats. I. Tonic excitability changes.", "content": "Immediate effects of total visual deafferentation on single unit activity in the visual cortex of freely behaving cats. I. Tonic excitability changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365929"}
{"pmid": "4365933", "title": "Clostridium perfringens panophthalmitis.", "content": "Clostridium perfringens panophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365933"}
{"pmid": "4365932", "title": "Tumours of the orbit and the eye in Indonesia. A clincal-pathological correlation.", "content": "Tumours of the orbit and the eye in Indonesia. A clincal-pathological correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365932"}
{"pmid": "4365938", "title": "Methyl n-butyl ketone.", "content": "Methyl n-butyl ketone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365938"}
{"pmid": "4365939", "title": "Treatment of advanced primary liver carcinoma using intermittent intra-arterial nitrogen mustard.", "content": "Treatment of advanced primary liver carcinoma using intermittent intra-arterial nitrogen mustard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365939"}
{"pmid": "4365940", "title": "Genital herpes in guinea-pigs. An experimental model with Herpesvirus hominis.", "content": "Genital herpes in guinea-pigs. An experimental model with Herpesvirus hominis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365940"}
{"pmid": "4365941", "title": "Simian virus 40 in a human cancer.", "content": "Simian virus 40 in a human cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365941"}
{"pmid": "4365934", "title": "Metabolism and action of the hormone vitamin D. Its relation to diseases of calcium homeostasis.", "content": "Metabolism and action of the hormone vitamin D. Its relation to diseases of calcium homeostasis. Extensive experimental evidence has established a significant role of calciferol in the maintenance of normal calcium homeostasis. Present knowledge indicates that vitamin D(3) must first be converted to 25-OH-D(3) and then to 1,25(OH)(2)D(3), the most active known form of the steroid. Many of the factors regulating the rate of production of this last steroid from its precurser have been evaluated, and the concept that vitamin D functions as a steroid hormone seems to be well established. Deranged action of calciferol, caused by impaired metabolism of the steroid or through altered sensitivity of target tissues, may be involved in the pathophysiology of several disease states with abnormal calcium metabolism. It is noted that liver disease, osteomalacia due to anticonvulsant therapy, chronic renal failure, hypophosphatemic rickets, hypoparathyroidism, hyperparathyroidism, sarcoidosis and idiopathic hypercalciuria have possible relation to alterations in metabolism or action of vitamin D. The future clinical availability of 1,25(OH)(2)D(3) and other analogs of this steroid may offer potential therapeutic benefit in the treatment of certain of the disease entities discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365934"}
{"pmid": "4365942", "title": "Outline structure of cytochrome c3 and consideration of its properties.", "content": "Outline structure of cytochrome c3 and consideration of its properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365942"}
{"pmid": "4365943", "title": "Congenital corneal clouding with abnormal systemic storage bodies: a new variant of mucolipidosis.", "content": "Congenital corneal clouding with abnormal systemic storage bodies: a new variant of mucolipidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365943"}
{"pmid": "4365944", "title": "Serologic responses to herpes simplex virus in rabbits: complement-requiring neutralizing, conventional neutralizing, and passive hemagglutinating antibodies.", "content": "Serologic responses to herpes simplex virus in rabbits: complement-requiring neutralizing, conventional neutralizing, and passive hemagglutinating antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365944"}
{"pmid": "4365945", "title": "Pathogenesis of pulmonary cytomegalovirus infection in immunosuppressed mice.", "content": "Pathogenesis of pulmonary cytomegalovirus infection in immunosuppressed mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365945"}
{"pmid": "4365946", "title": "The effect of cholera enterotoxin on steroidogenesis in cultured adrenal tumor cells.", "content": "The effect of cholera enterotoxin on steroidogenesis in cultured adrenal tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365946"}
{"pmid": "4365948", "title": "Bacterial interference among strains of Staphylococcus aureus in man.", "content": "Bacterial interference among strains of Staphylococcus aureus in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365948"}
{"pmid": "4365947", "title": "Urinary tract infection and pyelonephritis due to Escherichia coli in dogs infected with canine adenovirus.", "content": "Urinary tract infection and pyelonephritis due to Escherichia coli in dogs infected with canine adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365947"}
{"pmid": "4365949", "title": "Fecal excretion of cytomegalovirus in disseminated cytomegalic inclusion disease.", "content": "Fecal excretion of cytomegalovirus in disseminated cytomegalic inclusion disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365949"}
{"pmid": "4365950", "title": "Plasma proinsulin. Comparison of insulin specific protease and gel filtration assays.", "content": "Plasma proinsulin. Comparison of insulin specific protease and gel filtration assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365950"}
{"pmid": "4365955", "title": "Influence of dietary protein on 6- and 9-desaturation of fatty acids in rats of different ages and in different seasons.", "content": "Influence of dietary protein on 6- and 9-desaturation of fatty acids in rats of different ages and in different seasons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365955"}
{"pmid": "4365956", "title": "Occurrence of Parkinson's disease in black patients at Charity Hospital in New Orleans.", "content": "Occurrence of Parkinson's disease in black patients at Charity Hospital in New Orleans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365956"}
{"pmid": "4365957", "title": "Lipid cerebrospinal fluid in a patient with cerebral hemorrhage.", "content": "Lipid cerebrospinal fluid in a patient with cerebral hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365957"}
{"pmid": "4365953", "title": "Plasma vitamin A and E levels in children with familial type II hyperlipoproteinemia during therapy with diet and cholestyramine resin.", "content": "Plasma vitamin A and E levels in children with familial type II hyperlipoproteinemia during therapy with diet and cholestyramine resin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365953"}
{"pmid": "4365958", "title": "Sleep epilepsy: its pattern and prognosis.", "content": "Sleep epilepsy: its pattern and prognosis. In a series of 645 patients with epilepsy only 38 had attacks exclusively during sleep. A further 111 had attacks while waking and sleeping. The total number of patients whose epilepsy started with sleep attacks and who later developed attacks when waking increased with each successive year. The prognosis of sleep epilepsy is important in relation to the granting of driving licences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365958"}
{"pmid": "4365960", "title": "Letter: Unsuspected cytomegalic mononucleosis.", "content": "Letter: Unsuspected cytomegalic mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365960"}
{"pmid": "4365954", "title": "Vitamin A and glycosaminoglycan metabolism in rats.", "content": "Vitamin A and glycosaminoglycan metabolism in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365954"}
{"pmid": "4365951", "title": "Relation of hypertension to changes in the arteries.", "content": "Relation of hypertension to changes in the arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365951"}
{"pmid": "4365959", "title": "EB virus and the treatment of lymphomas.", "content": "EB virus and the treatment of lymphomas. The high incidence of EB virus infections (and possibly of other viruses) in patients with African lymphoma and, to a lesser extent, in patients with lymphosarcoma in the temperate zones, is thought to be due to its being a passenger virus which persists in the human body and, since it is lymphotropic, presents an opportunistic infection of proliferating lymphoid cells. The thesis is put forward that by entering the cell nucleus, the virus renders malignant lymphoid cells more vulnerable to cytotoxic drugs. Hence a deliberate policy of EB virus inoculation before starting chemotherapy might achieve a more rapid response and longer remissions in indigenous lymphomas of the temperate zones, and might possibly render drug-resistant cases once more drug-sensitive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365959"}
{"pmid": "4365952", "title": "Renin and aldosterone and the pathogenesis of hypertensive vascular damage.", "content": "Renin and aldosterone and the pathogenesis of hypertensive vascular damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365952"}
{"pmid": "4365961", "title": "Letter: Mental changes in Parkinsonism.", "content": "Letter: Mental changes in Parkinsonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365961"}
{"pmid": "4365963", "title": "An unusual case of adenocarcinoma of the pancreas.", "content": "An unusual case of adenocarcinoma of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365963"}
{"pmid": "4365962", "title": "Metronidazole and amebiasis.", "content": "Metronidazole and amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365962"}
{"pmid": "4365964", "title": "A histological, histochemical and biochemical study of the effect of the toxin of lupinosis on murine liver.", "content": "A histological, histochemical and biochemical study of the effect of the toxin of lupinosis on murine liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365964"}
{"pmid": "4365966", "title": "Plasma corticotrophin levels during insulin-hypoglycaemia: comparison of radioimmunoassay and cytochemical bioassay.", "content": "Plasma corticotrophin levels during insulin-hypoglycaemia: comparison of radioimmunoassay and cytochemical bioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365966"}
{"pmid": "4365968", "title": "Mass determination of lipids with automated thermogravimetric analytical procedure.", "content": "Mass determination of lipids with automated thermogravimetric analytical procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365968"}
{"pmid": "4365967", "title": "DDT absorption and chylomicron transport in rat.", "content": "DDT absorption and chylomicron transport in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365967"}
{"pmid": "4365969", "title": "Radioimmunoassay for medroxyprogesterone acetate (Provera) using the 11alpha-hydroxy succinyl conjugate.", "content": "Radioimmunoassay for medroxyprogesterone acetate (Provera) using the 11alpha-hydroxy succinyl conjugate. The development of a radioimmunoassay for medroxyprogesterone acetate (MPA) employing rabbit antibodies made against a bovine serum albumin (BSA) conjugate of the hemisuccinate ester of 11alpha-hydroxy MPA are described.  The 11alpa-hydroxyl group was introduced into MPA by a series of chemical and microbiological transformations.  The acid succinate MPA was coupled to BSA by reacting it with N,N'-carbonyldiimidazole.  Cross-reactivities of several MPA analogs were compared suing rabbit antisera developed against the C-11 conjugate of MPA and goat antiserum developed against a C-3 conjugate of MPA.  Antibodies formed against the C-11 conjugate showed increased specificity to steroid analogs which changes in the C-21 side chain.  The profiles of serum MPA levels vs time, measured with both the C-3 and C-11 antisera, after oral drug administration to the monkey were similar.  After intramuscular drug administration to dogs, serum MPA levels measured with the C-3 antisera were consistently greater as compared with those with C-11 antisera.  Factors affecting precipitation of the antibody-antigen complex, assay precision, and assay sensitivity were evaluated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365969"}
{"pmid": "4365973", "title": "The cytochemical section assay for corticotrophin.", "content": "The cytochemical section assay for corticotrophin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365973"}
{"pmid": "4365972", "title": "Ectopic hormone production by non-endocrine tumours.", "content": "Ectopic hormone production by non-endocrine tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365972"}
{"pmid": "4365975", "title": "The redox bioassay technique for the direct assessment of pituitary adrenocorticotrophic activity in the rat.", "content": "The redox bioassay technique for the direct assessment of pituitary adrenocorticotrophic activity in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365975"}
{"pmid": "4365974", "title": "Validation of the redox cytochemical assay for corticotrophin.", "content": "Validation of the redox cytochemical assay for corticotrophin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365974"}
{"pmid": "4365977", "title": "Massive fetal ascites, urethral atresia, and cytomegalic inclusion disease.", "content": "Massive fetal ascites, urethral atresia, and cytomegalic inclusion disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365977"}
{"pmid": "4365978", "title": "Virus-like particles induced in guinea pig cells by 5-bromo-2'-deoxyuridine are morphologically similar to murine B-type virus.", "content": "Virus-like particles induced in guinea pig cells by 5-bromo-2'-deoxyuridine are morphologically similar to murine B-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365978"}
{"pmid": "4365979", "title": "Evidence that most noradrenaline is stored without ATP in sympathetic large dense core nerve vesicles.", "content": "Evidence that most noradrenaline is stored without ATP in sympathetic large dense core nerve vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365979"}
{"pmid": "4365981", "title": "Individual versus group aftercare treatment.", "content": "Individual versus group aftercare treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365981"}
{"pmid": "4365980", "title": "Mixed Müllerian tumors of the oviduct.", "content": "Mixed Müllerian tumors of the oviduct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365980"}
{"pmid": "4365984", "title": "Auxiliary structures of tuberous organ (electroreceptor) of Sternarchus albifrons (Gymnotidae).", "content": "Auxiliary structures of tuberous organ (electroreceptor) of Sternarchus albifrons (Gymnotidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365984"}
{"pmid": "4365985", "title": "The giant melanosome: a model of deranged melanosome-morphogenesis.", "content": "The giant melanosome: a model of deranged melanosome-morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365985"}
{"pmid": "4365986", "title": "Striated and crystalline inclusions in the nuclei and cytoplasm of intact yeast cells and yeast protoplasts.", "content": "Striated and crystalline inclusions in the nuclei and cytoplasm of intact yeast cells and yeast protoplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365986"}
{"pmid": "4365988", "title": "Letter: Acute poliomyelitis disputed.", "content": "Letter: Acute poliomyelitis disputed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365988"}
{"pmid": "4365987", "title": "Cerebral blood flow in acute hypertension.", "content": "Cerebral blood flow in acute hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365987"}
{"pmid": "4365989", "title": "Proceedings: Interactions of separate types of cells during normal and neoplastic mammary gland growth.", "content": "Proceedings: Interactions of separate types of cells during normal and neoplastic mammary gland growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365989"}
{"pmid": "4365990", "title": "Proceedings: Hormones and other factors controlling growth in the mammary gland: a review.", "content": "Proceedings: Hormones and other factors controlling growth in the mammary gland: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365990"}
{"pmid": "4365992", "title": "Special diet for familial type II hyperlipoproteinemia.", "content": "Special diet for familial type II hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365992"}
{"pmid": "4365991", "title": "Proceedings: Mammogenesis in transsexuals.", "content": "Proceedings: Mammogenesis in transsexuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365991"}
{"pmid": "4365994", "title": "Bone marrow biopsy in malignant disease.", "content": "Bone marrow biopsy in malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365994"}
{"pmid": "4365993", "title": "Pitfalls in the diagnosis of low-back and leg pain.", "content": "Pitfalls in the diagnosis of low-back and leg pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365993"}
{"pmid": "4365995", "title": "Brain scanning and conventional neuroradiologic methods in intracranial tumours. Scanning with 99Tcm and a gamma camera.", "content": "Brain scanning and conventional neuroradiologic methods in intracranial tumours. Scanning with 99Tcm and a gamma camera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365995"}
{"pmid": "4365997", "title": "Experience with intraoperative echoencephalography in cerebral mass lesions.", "content": "Experience with intraoperative echoencephalography in cerebral mass lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365997"}
{"pmid": "4365996", "title": "Cerebral scintiphotos with 113mIn.", "content": "Cerebral scintiphotos with 113mIn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365996"}
{"pmid": "4365998", "title": "Unusual myelographic appearances of the lumbosacral radicular sheaths.", "content": "Unusual myelographic appearances of the lumbosacral radicular sheaths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365998"}
{"pmid": "4365999", "title": "Electron microscopic observations of human retinitis pigmentosa, dominantly inherited.", "content": "Electron microscopic observations of human retinitis pigmentosa, dominantly inherited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4365999"}
{"pmid": "4366000", "title": "Retinal degeneration in monkeys induced by deficiencies of vitamin E or A.", "content": "Retinal degeneration in monkeys induced by deficiencies of vitamin E or A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366000"}
{"pmid": "4366001", "title": "Primary malignant lymphoma of the bladder: case report and review of the literature.", "content": "Primary malignant lymphoma of the bladder: case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366001"}
{"pmid": "4366003", "title": "Nuclear bodies in papillary carcinomas of the human thyroid gland.", "content": "Nuclear bodies in papillary carcinomas of the human thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366003"}
{"pmid": "4366002", "title": "Association between herpes hominis type 2 and the male genitourinary tract.", "content": "Association between herpes hominis type 2 and the male genitourinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366002"}
{"pmid": "4366004", "title": "Megakaryocytes in the May-Heggelin anomaly.", "content": "Megakaryocytes in the May-Heggelin anomaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366004"}
{"pmid": "4366005", "title": "Hepatic injury associated with penicillin therapy.", "content": "Hepatic injury associated with penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366005"}
{"pmid": "4366006", "title": "Functional black adenoma of the adrenal gland. Light and electron microscopical study.", "content": "Functional black adenoma of the adrenal gland. Light and electron microscopical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366006"}
{"pmid": "4366007", "title": "An electrophoretic study of the negative correlation of certain carboxylesterases to insecticide resistance in Musca domestica L.", "content": "An electrophoretic study of the negative correlation of certain carboxylesterases to insecticide resistance in Musca domestica L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366007"}
{"pmid": "4366008", "title": "Electron microscope studies on the dissociation of actomyosin by pyrophosphate.", "content": "Electron microscope studies on the dissociation of actomyosin by pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366008"}
{"pmid": "4366009", "title": "Effects of GABA on presynaptic nerve terminals in bullfrog (Rana catesbiana) sympathetic ganglia.", "content": "Effects of GABA on presynaptic nerve terminals in bullfrog (Rana catesbiana) sympathetic ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366009"}
{"pmid": "4366010", "title": "Light-microscopic demonstration of drug-induced myelin bodies in the liver of rats.", "content": "Light-microscopic demonstration of drug-induced myelin bodies in the liver of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366010"}
{"pmid": "4366011", "title": "A renal tumour of the nephroblastoma type in Praomys (Mastomys) natalensis.", "content": "A renal tumour of the nephroblastoma type in Praomys (Mastomys) natalensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366011"}
{"pmid": "4366013", "title": "Excretion of equine infectious anemia virus from horses infected with the virus.", "content": "Excretion of equine infectious anemia virus from horses infected with the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366013"}
{"pmid": "4366012", "title": "In vitro synthesis of an ACTH-like hormone and human chorionic somatomammotrophin by placental and amniotic cells.", "content": "In vitro synthesis of an ACTH-like hormone and human chorionic somatomammotrophin by placental and amniotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366012"}
{"pmid": "4366015", "title": "Studies on the replicase of encephalomyocarditis virus.", "content": "Studies on the replicase of encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366015"}
{"pmid": "4366014", "title": "SV40 DNA molecules which contain host cell DNA.", "content": "SV40 DNA molecules which contain host cell DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366014"}
{"pmid": "4366016", "title": "Prostaglandins and cancer: an update.", "content": "Prostaglandins and cancer: an update.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366016"}
{"pmid": "4366017", "title": "Cyclic AMP, prostaglandins, and the control of cell proliferation.", "content": "Cyclic AMP, prostaglandins, and the control of cell proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366017"}
{"pmid": "4366018", "title": "Effects of prostaglandins on the stomach and the intestine.", "content": "Effects of prostaglandins on the stomach and the intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366018"}
{"pmid": "4366020", "title": "Morphology of the electromotor system in the spinal cord of the electric eel, Electrophorus electricus.", "content": "Morphology of the electromotor system in the spinal cord of the electric eel, Electrophorus electricus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366020"}
{"pmid": "4366019", "title": "Synaptic organization of the substantia gelatinosa glomeruli in the spinal trigeminal nucleus of the adult cat.", "content": "Synaptic organization of the substantia gelatinosa glomeruli in the spinal trigeminal nucleus of the adult cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366019"}
{"pmid": "4366021", "title": "Viral DNA synthesis in cells infected by temperature-sensitive mutants of simian virus 40.", "content": "Viral DNA synthesis in cells infected by temperature-sensitive mutants of simian virus 40. Temperature-sensitive mutants of simian virus 40 (SV40) have been classified as those that are blocked prior to viral DNA synthesis at the restrictive temperature, \"early\" mutants, and those harboring a defect later in the replication cycle, \"late\" mutants. Mutants of the A and D complementation groups are early, those of the B, C, and BC groups are late. Our results confirm earlier reports that A mutants are defective in a function required for the initiation of each round of viral DNA synthesis. D mutants, on the other hand, continue viral DNA replication at the restrictive temperature after preincubation at the permissive temperature. The length of time required for D function to be expressed at the permissive temperature-after which infection proceeds unabated on shifting of the cultures to the restrictive temperature-is 10 to 20 h. The viral DNA synthesized in D mutants under these conditions progresses in normal fashion through replicative intermediate molecules to mature component I and II DNA molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366021"}
{"pmid": "4366022", "title": "Genetic analysis of a temperature-resistant revertant of the conditional lethal Escherichia coli double mutant polA12 uvrE502.", "content": "Genetic analysis of a temperature-resistant revertant of the conditional lethal Escherichia coli double mutant polA12 uvrE502. Conditional lethality of the Escherichia coli polA12 uvrE502 double mutant may be overcome by a mutation that has been termed polA350. The polA350 mutation restored the polymerizing activity of deoxyribonucleic acid polymerase I at 42 C in the polA12 mutant and partially suppressed ultraviolet (UV) and methylmethane sulfonate sensitivities of the polA12. Mapping experiments have located polA350 between metE and polA12, very close to the latter. The strain carrying polA12 polA350 and recB21 was viable at 42 C. The effects of the recB21 and polA12 polA350 combination on the UV sensitivity were additive. The triple mutant polA12 polA350 uvrE502 was more UV sensitive than the single uvrE502 mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366022"}
{"pmid": "4366023", "title": "Biosynthetic dihydroorotate dehydrogenase from Lactobacillus bulgaricus: partial characterization of the enzyme.", "content": "Biosynthetic dihydroorotate dehydrogenase from Lactobacillus bulgaricus: partial characterization of the enzyme. Some of the catalytic properties of the biosynthetic dihydroorotate dehydrogenase purified from an anaerobic bacterium, Lactobacillus bulgaricus, are described. Studies with p-hydroxymercuribenzoate, N-ethylmaleimide, and mercuric chloride showed that sulfhydryl groups are necessary for transfer of electrons from dihydroorotate to a variety of electron acceptors. Protection studies with substrates for the enzyme indicated that free sulfhydryl groups at or near the active center are required for catalytic activity. Evidence is presented for the production of superoxide free radicals during reaction of the enzyme with molecular oxygen. Inhibitor studies with Tiron indicated that reduction of cytochrome c by the enzyme may involve the superoxide free radical as an intermediate. Orotate, one of the substrates for the enzyme, has been found to be a competitive inhibitor for the dihydroorotate site. The K(i) for orotate as estimated by several techniques is 0.1 mM. The K(m) for dihydroorotate with ferricyanide as the electron acceptor is estimated to be 0.5 mM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366023"}
{"pmid": "4366024", "title": "Pleiotropic alteration of activities of several toxins and enzymes in mutants of Staphylococcus aureus.", "content": "Pleiotropic alteration of activities of several toxins and enzymes in mutants of Staphylococcus aureus. Pleiotropic alteration of several genetic characters including toxin production was quantitatively shown with a strain of Staphylococcus aureus of phage type 80, 81 which had been given a very specific genetic marker (temperature sensitivity of mannitol fermentation) to avoid confusion by contamination. Thus, alpha-hemolysin hyperproducers obtained by N-methyl-N'-nitro-N-nitrosoguanidine (NTG) mutagenesis were very often hyperproducers of DNase, coagulase, and protease. Their colonies were less yellow than the parent. DNase hyperproducers obtained after NTG mutagenesis were also often hyperproducers of alpha-hemolysin, coagulase, and protease, with colonies less yellow than the parent. Almost all of the revertants obtained by mutagenesis with ethyl methane sulfonate with respect to alpha-hemolysin or DNase were shown to have simultaneously become hypoproducers of alpha-hemolysin, DNase, and protease. Since the pleiotropic alteration of multiple functions was thus quantitatively confirmed, the mechanism underlying this phenomenon should probably be related to a regulatory mechanism common to them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366024"}
{"pmid": "4366025", "title": "Ribitol catabolic pathway in Klebsiella aerogenes.", "content": "Ribitol catabolic pathway in Klebsiella aerogenes. In Klebsiella aerogenes W70, there is an inducible pathway for the catabolism of ribitol consisting of at least two enzymes, ribitol dehydrogenase (RDH) and d-ribulokinase (DRK). These two enzymes are coordinately controlled and induced in response to d-ribulose, an intermediate of the pathway. Whereas wild-type K. aerogenes W70 are unable to utilize xylitol as a carbon and energy source, mutants constitutive for the ribitol pathway are able to utilize RDH to oxidize the unusual pentitol, xylitol, to d-xylulose. These mutants are able to grow on xylitol, presumably by utilization of the d-xylulose produced. Mutants constitutive for l-fucose isomerase can utilize the isomerase to convert d-arabinose to d-ribulose. In the presence of d-ribulose, RDH and DRK are induced, and such mutants are thus able to phosphorylate the d-ribulose by using the DRK of the ribitol pathway. Derivatives of an l-fucose isomerase-constitutive mutant were plated on d-arabinose, ribitol, and xylitol to select and identify mutations in the ribitol pathway. Using the transducing phage PW52, we were able to demonstrate genetic linkage of the loci involved. Three-point crosses, using constitutive mutants as donors and RDH(-), DRK(-) double mutants as recipients and selecting for DRK(+) transductants on d-arabinose, resulted in DRK(+)RDH(+)-constitutive, DRK(+)RDH(+)-inducible, and DRK(+)RDH(-)-inducible transductants but no detectable DRK(+)RDH(-) constitutive transductants, data consistent with the order rbtC-rbtD-rbtK, where rbtC is a control site and rbtD and rbtK correspond to the sites for the sites for the enzymes RDH and DRK, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366025"}
{"pmid": "4366028", "title": "Isolating peripheral nerve activity with respect to propagation velocity.", "content": "Isolating peripheral nerve activity with respect to propagation velocity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366028"}
{"pmid": "4366027", "title": "Regulation of rabbit liver fructose-1,6-diphosphatase. II. Modification by lysosomal cathepsin B1 from the same cell.", "content": "Regulation of rabbit liver fructose-1,6-diphosphatase. II. Modification by lysosomal cathepsin B1 from the same cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366027"}
{"pmid": "4366026", "title": "D-Arabitol catabolic pathway in Klebsiella aerogenes.", "content": "D-Arabitol catabolic pathway in Klebsiella aerogenes. Klebsiella aerogenes strain W70 has an inducible pathway for the degradation of d-arabitol which is comparable to the one found in Aerobacter aerogenes strain PRL-R3. The pathway is also similar to the pathway of ribitol catabolism in that it is composed of a pentitol dehydrogenase, d-arabitol dehydrogenase (ADH), and a pentulokinase, d-xylulokinase (DXK). These two enzymes are coordinately controlled and induced in response to d-arabitol, the apparent inducer of synthesis of these enzymes. We obtained mutants which lacked a functional d-xylose pathway and were constitutive for the ribitol catabolic pathway. These mutants were able to grow on the unusual pentitol, xylitol, only if they contained the functional DXK of the d-arabitol pathway. This provided us with a specific selection technique for DXK(+) transductants. As in A. aerogenes, mutants constitutive for ADH were able to use this enzyme to convert the hexitol d-mannitol to d-fructose. With mutants blocked in the normal d-mannitol catabolic pathway, growth on d-mannitol became a test for ADH constitutivity. Growth of such mutants on xylitol, d-arabitol, and d-mannitol was utilized to classify transductants in mapping, by transductional analysis, the loci involved in d-arabitol utilization. Three-point crosses gave the order dalK-dalD-dalC, where dalK is the DXK structural gene, dalD is the ADH structural gene, and dalC is a regulatory site controlling synthesis of both enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366026"}
{"pmid": "4366030", "title": "Morphologic abnormalities in human infant cerebral white matter related to gestational and postnatal age.", "content": "Morphologic abnormalities in human infant cerebral white matter related to gestational and postnatal age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366030"}
{"pmid": "4366032", "title": "Ultrastructural changes in germinating ascospores of Saccharomyces cerevisiae.", "content": "Ultrastructural changes in germinating ascospores of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366032"}
{"pmid": "4366033", "title": "The cytochrome system in Mycobacterium lepraemurium.", "content": "The cytochrome system in Mycobacterium lepraemurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366033"}
{"pmid": "4366034", "title": "Histoenzymological demonstration of certain phosphatases in the intestinal mucosa of common garden lizard Calotes versicolor.", "content": "Histoenzymological demonstration of certain phosphatases in the intestinal mucosa of common garden lizard Calotes versicolor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366034"}
{"pmid": "4366037", "title": "Hypoglycemia with primary liver cell carcinoma.", "content": "Hypoglycemia with primary liver cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366037"}
{"pmid": "4366038", "title": "The acupunture point.", "content": "The acupunture point.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366038"}
{"pmid": "4366044", "title": "The influence of presleep suggestions on dream content: evidence and methodological problems.", "content": "The influence of presleep suggestions on dream content: evidence and methodological problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366044"}
{"pmid": "4366045", "title": "Proceedings: The oxidation of catecholamines by hemepeptide obtained from enzymatically digested yeast cytochrome C.", "content": "Proceedings: The oxidation of catecholamines by hemepeptide obtained from enzymatically digested yeast cytochrome C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366045"}
{"pmid": "4366047", "title": "Hepatic cell adenoma: A report of four cases.", "content": "Hepatic cell adenoma: A report of four cases. Four patients with hepatic cell adenoma have been treated at the UCLA Hospital since 1965. The most recent was a 22-year-old woman who underwent subtotal resection of a giant hepatic cell adenoma after an unusual and confusing clinical presentation. The tumor may be the largest reported to date and may have excreted metabolically-active substances. Increased familiarity with the varying clinical and radiographic presentations of these rare tumors may facilitate earlier diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366047"}
{"pmid": "4366046", "title": "Ultrastructure of the fetal rat adenohypophysis.", "content": "Ultrastructure of the fetal rat adenohypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366046"}
{"pmid": "4366048", "title": "The retina and optic nerve.", "content": "The retina and optic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366048"}
{"pmid": "4366050", "title": "The effect of plasma cortisol concentration on the pituitary adrenal response elicited by electrical stimulation of the infundibular area of the awake unrestrained cat.", "content": "The effect of plasma cortisol concentration on the pituitary adrenal response elicited by electrical stimulation of the infundibular area of the awake unrestrained cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366050"}
{"pmid": "4366049", "title": "Vasodilator drugs in the treatment of peripheral arterial insufficiency.", "content": "Vasodilator drugs in the treatment of peripheral arterial insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366049"}
{"pmid": "4366051", "title": "Experimental studies of the endolymphatic radiotherapy.", "content": "Experimental studies of the endolymphatic radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366051"}
{"pmid": "4366052", "title": "Expression of the familial hypercholesterolemia gene in heterozygotes: mechanism for a dominant disorder in man.", "content": "Expression of the familial hypercholesterolemia gene in heterozygotes: mechanism for a dominant disorder in man. Studies in ctltured fibroblasts indicate that the primary genetic abnormality in familial hypercholesterolemia involves a deficiency in a cell surface receptor for low density lipoproteins (LDL). In normal cells, binding of LDL to this receptor regulates cholesterol metabolism by suppressing cholesterol synthesis and increasing LDL degradation. In cells from heterozygotes, a 60 percent reduction in LDL receptors leads to a concentration-dependent defect in regulation, so that attainment of equal rates of cholesterol synthesis and LDL degradation in normal and heterozygous cells requires a two- to threefold higher concentration of LDL in the heterozygote. The identification of this genetic regulatory defect in fibroblasts of heterozygotes makes available an in vitro system for studying the effects of a dominant mutation on gene expression in mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366052"}
{"pmid": "4366053", "title": "The effects of Escherichia coli endotoxin and ACTH on the plasma zinc concentration in the domestic fowl.", "content": "The effects of Escherichia coli endotoxin and ACTH on the plasma zinc concentration in the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366053"}
{"pmid": "4366054", "title": "Collagenolytic enzymes and acid-proteinase activity in granuloma tissue.", "content": "Collagenolytic enzymes and acid-proteinase activity in granuloma tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366054"}
{"pmid": "4366055", "title": "Loss of serum protein from hepatoma-bearing animals.", "content": "Loss of serum protein from hepatoma-bearing animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366055"}
{"pmid": "4366057", "title": "The lipoprotein apoproteins. Their role in normal lipid transport and dyslipoproteinemia.", "content": "The lipoprotein apoproteins. Their role in normal lipid transport and dyslipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366057"}
{"pmid": "4366056", "title": "Comparison of MHG virus with mouse encephalomyelitis viruses.", "content": "Comparison of MHG virus with mouse encephalomyelitis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366056"}
{"pmid": "4366058", "title": "Neuromuscular transmission in myasthenia gravis studied with single fibre electromyography.", "content": "Neuromuscular transmission in myasthenia gravis studied with single fibre electromyography. Patients with myasthenia gravis have been investigated with single fibre electromyography. In all myasthenic muscles recordings were obtained where there was an increase of the jitter and occasional blocking of different degree of single fibre action potentials. The jitter is the variability at consecutive discharges in the time interval between action potentials from two muscle fibres from the same motor unit. During prolonged activity the jitter increased and blockings occurred more and more frequently. The size of the jitter and the degree of blocking also depended on the discharge rate. At a low rate the jitter was lower and the degree of blocking less than at the high rate. Injection of edrophonium could decrease or increase the jitter or leave it unaffected. Single fibre electromyography is a sensitive way of studying the transmission in individual motor end-plates in myasthenia gravis and is also a valuable diagnostic aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366058"}
{"pmid": "4366060", "title": "Role of extrapulmonary conversion in mediating the systemic pressor activity of angiotensin I.", "content": "Role of extrapulmonary conversion in mediating the systemic pressor activity of angiotensin I. The effect of antibodies against angiotensin II (AII) on systemic pressor responses to intravenously injected AII and angiotensin I (AI) was studied in a group of bioassay rats. AII antibody was only 29% as effective in neutralizing AI given intravenously as it was in neutralizing AII injected by the same route. Control plasma caused no change in the relative potencies of AI and AII. In a further series of experiments, AII antibody was significantly less effective in blocking intra-arterial AI than in blocking intravenous AI. The potency of intra-arterial AI, initially less than that of intravenous AI, became nearly twice that of intravenous AI after antibody administration, a result which could not occur if AI were inactive before lung transit. Thus, AI can elicit systemic pressor activity independently of pulmonary conversion to AII. However, since the intra-arterial AI responses were abolished by an inhibitor of angiotensin-converting enzyme, the activity would appear to be mediated by peripheral conversion to AII rather than by an intrinsic action of the decapeptide. Both series of experiments suggest that the efficacy of AII antibody in abolishing the systemic pressor activity of AI is highly dependent on the site of conversion of the AI to AII. The occurrence of localized intramural conversion of AI to AII near arteriolar receptors in vivo may so minimize exposure of the liberated AII to circulating antibody as to render AII immunization an inefficient means of blocking endogenous pressor activity of the renin-angiotensin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366060"}
{"pmid": "4366059", "title": "Oncornavirus expression in human x mouse hybrid cells segregating mouse chromosomes.", "content": "Oncornavirus expression in human x mouse hybrid cells segregating mouse chromosomes. Human x mouse hybrid clones obtained by fusing transformed human (VA2) cells with embryonic mouse brain cells were tested for their ability to spontaneously express type C virus particles. It had been previously shown that these hybrid cells preferentially retained human chromosomes while mouse chromosomes were lost. The culture fluid from one cell line was found to contain type C particle markers in abundance, and typical budding C particles were observed in the cells by electron microscopy. In contrast, no particle markers were detected in the culture fluid from parental cells and several other hybrid cell lines. Subclones of the virus-positive cell line continued to lose mouse chromosomes and were found to vary more than 100-fold in their culture fluid DNA polymerase activity. The hybrid cell viruses, termed HMV1, banded in a sucrose gradient between 1.14 and 1.16 g/ml, possessed viral group-specific antigens, and exhibited B-tropic host range for replication in mouse embryo cells, but did not replicate in human cells when directly applied. The virus did not transform mouse cells but was able to rescue the defective murine sarcoma virus from sarcoma-positive, helper-virus-negative cells. Activity of the DNA polymerase associated with HMV1 was similar to the activity of Rauscher murine leukemia virus (MuLV) DNA polymerase in its preference for poly(rA) over poly(dA) as a template, use of endogenous template, detergent requirement, and inhibition by antiserum directed against MuLV.DNA polymerase. The results suggest that human x mouse hybrid cells segregating mouse chromosomes can spontaneously express endogenous type C viruses and that such hybrid cell lines may be used for the isolation of latent mammalian oncornaviruses and analysis of viral gene regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366059"}
{"pmid": "4366061", "title": "Control of derepressed beta-galactosidase synthesis in Escherichia coli.", "content": "Control of derepressed beta-galactosidase synthesis in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366061"}
{"pmid": "4366063", "title": "Functional and morphological effects of hypophysectomy and androgen replacement in the rabbit epididymis.", "content": "Functional and morphological effects of hypophysectomy and androgen replacement in the rabbit epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366063"}
{"pmid": "4366065", "title": "Induction and isolation of auxotrophic mutants in mammalian cells.", "content": "Induction and isolation of auxotrophic mutants in mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366065"}
{"pmid": "4366066", "title": "Isolation of temperature-sensitive mutants of mammalian cells.", "content": "Isolation of temperature-sensitive mutants of mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366066"}
{"pmid": "4366067", "title": "Methods for obtaining revertants of transformed cells.", "content": "Methods for obtaining revertants of transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366067"}
{"pmid": "4366068", "title": "Uses of enucleated cells.", "content": "Uses of enucleated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366068"}
{"pmid": "4366070", "title": "Ionic coupling between nonexcitable cells in culture.", "content": "Ionic coupling between nonexcitable cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366070"}
{"pmid": "4366069", "title": "Enucleation of somatic cells with cytochalasin B.", "content": "Enucleation of somatic cells with cytochalasin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366069"}
{"pmid": "4366072", "title": "Persistent changes induced by subcarcinogenic doses of 3'-methyl-4-(dimethylamino)azobenzene in rat liver.", "content": "Persistent changes induced by subcarcinogenic doses of 3'-methyl-4-(dimethylamino)azobenzene in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366072"}
{"pmid": "4366071", "title": "Methods of cell transformation by tumor viruses.", "content": "Methods of cell transformation by tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366071"}
{"pmid": "4366073", "title": "Effect of N-(3,5-dichlorophenyl)succinimide on the histological pattern and incidence of kidney tumors in rats induced by dimethylnitrosoamine.", "content": "Effect of N-(3,5-dichlorophenyl)succinimide on the histological pattern and incidence of kidney tumors in rats induced by dimethylnitrosoamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366073"}
{"pmid": "4366074", "title": "Variation in the mode of sugar transport among normal and tumor cells.", "content": "Variation in the mode of sugar transport among normal and tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366074"}
{"pmid": "4366076", "title": "Episodic secretion of aldosterone in primary aldosteronism: relationship to cortisol.", "content": "Episodic secretion of aldosterone in primary aldosteronism: relationship to cortisol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366076"}
{"pmid": "4366077", "title": "Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase.", "content": "Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366077"}
{"pmid": "4366079", "title": "Ribosomal activities dependent on elongation factors T and G. Effects of methanol.", "content": "Ribosomal activities dependent on elongation factors T and G. Effects of methanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366079"}
{"pmid": "4366075", "title": "Effect of Clostridium perfringens phospholipase C(alpha-toxin) on the human diploid fibroblast membrane.", "content": "Effect of Clostridium perfringens phospholipase C(alpha-toxin) on the human diploid fibroblast membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366075"}
{"pmid": "4366078", "title": "Phosphorylation of N-protected deoxyoligonucleotides by T4 polynucleotide kinase.", "content": "Phosphorylation of N-protected deoxyoligonucleotides by T4 polynucleotide kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366078"}
{"pmid": "4366080", "title": "Conformation of nicotinamide adenine dinucleotide bound to cytoplasmic malate dehydrogenase.", "content": "Conformation of nicotinamide adenine dinucleotide bound to cytoplasmic malate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366080"}
{"pmid": "4366081", "title": "Polynucleotides containing 2'-amino-2'-deoxyribose and 2'-azido-2'-deoxyribose.", "content": "Polynucleotides containing 2'-amino-2'-deoxyribose and 2'-azido-2'-deoxyribose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366081"}
{"pmid": "4366082", "title": "Acidophilic activation of steroid hormone receptors.", "content": "Acidophilic activation of steroid hormone receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366082"}
{"pmid": "4366083", "title": "Gonadotropin regulation of nucleotide biosynthesis in corpus luteum.", "content": "Gonadotropin regulation of nucleotide biosynthesis in corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366083"}
{"pmid": "4366084", "title": "Studies on the function of central noradrenergic neurons.", "content": "Studies on the function of central noradrenergic neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366084"}
{"pmid": "4366085", "title": "Shape of the hydrophobic barrier of phospholipid bilayers (evidence for water penetration in biological membranes).", "content": "Shape of the hydrophobic barrier of phospholipid bilayers (evidence for water penetration in biological membranes).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366085"}
{"pmid": "4366086", "title": "Regulation of glycolysis in the early development of fish embryos.", "content": "Regulation of glycolysis in the early development of fish embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366086"}
{"pmid": "4366087", "title": "Galactosyl-diglyceride from Actinomyces viscosus.", "content": "Galactosyl-diglyceride from Actinomyces viscosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366087"}
{"pmid": "4366090", "title": "Virus, the primordial parasite, and man.", "content": "Virus, the primordial parasite, and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366090"}
{"pmid": "4366088", "title": "Mass spectra of complex molecules. I. Chemical ionization of sphingolipids.", "content": "Mass spectra of complex molecules. I. Chemical ionization of sphingolipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366088"}
{"pmid": "4366091", "title": "Herpesviruses, latency and cancer: a biochemical approach.", "content": "Herpesviruses, latency and cancer: a biochemical approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366091"}
{"pmid": "4366093", "title": "The Wilms' tumour--old and new facts. I. Clinical features and tumour biology.", "content": "The Wilms' tumour--old and new facts. I. Clinical features and tumour biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366093"}
{"pmid": "4366094", "title": "The Wilms' tumour--old and new facts. 3. Special problems in therapy.", "content": "The Wilms' tumour--old and new facts. 3. Special problems in therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366094"}
{"pmid": "4366095", "title": "Intraoperative upper gastrointestinal endoscopy and biopsy.", "content": "Intraoperative upper gastrointestinal endoscopy and biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366095"}
{"pmid": "4366096", "title": "Granuloma annulare and vitamin D resistant rickets.", "content": "Granuloma annulare and vitamin D resistant rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366096"}
{"pmid": "4366098", "title": "Radioimmunoassay of pituitary gonadotropins: serum levels in normal women and those with gonadal dysfunction.", "content": "Radioimmunoassay of pituitary gonadotropins: serum levels in normal women and those with gonadal dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366098"}
{"pmid": "4366099", "title": "The role of estradiol in the equilibrium binding of estrogen receptor to rabbit uterine chromatin.", "content": "The role of estradiol in the equilibrium binding of estrogen receptor to rabbit uterine chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366099"}
{"pmid": "4366100", "title": "Effect of dibutyryl cyclic amp on glucose-6-phosphatase activity in human fetal liver explants.", "content": "Effect of dibutyryl cyclic amp on glucose-6-phosphatase activity in human fetal liver explants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366100"}
{"pmid": "4366102", "title": "Effects of decapitation, ether and pentobarbital on guanosine 3',5'-phosphate and adenosine 3',5'-phosphate levels in rat tissues.", "content": "Effects of decapitation, ether and pentobarbital on guanosine 3',5'-phosphate and adenosine 3',5'-phosphate levels in rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366102"}
{"pmid": "4366101", "title": "Effect of triamcinolone treatment, starvation and diabetes on rat liver protein kinase activity.", "content": "Effect of triamcinolone treatment, starvation and diabetes on rat liver protein kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366101"}
{"pmid": "4366103", "title": "The physical chemistry of hemes and hemopeptides. 3. Synthesis and physicochemical properties of cytochrome c-related heme--pentapeptide soluble in organic solvents.", "content": "The physical chemistry of hemes and hemopeptides. 3. Synthesis and physicochemical properties of cytochrome c-related heme--pentapeptide soluble in organic solvents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366103"}
{"pmid": "4366106", "title": "The enrichment of adenylate cyclase in the plasma membrane and golgi subcellular fractions of porcine adenohypophysis.", "content": "The enrichment of adenylate cyclase in the plasma membrane and golgi subcellular fractions of porcine adenohypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366106"}
{"pmid": "4366108", "title": "Role of the cell surface in growth and transformation.", "content": "Role of the cell surface in growth and transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366108"}
{"pmid": "4366105", "title": "Ultrastructure, steroidogenic potential, and energy metabolism of the Snell adrenocortical carcinoma 494. A comparison with normal adrenocortical tissue.", "content": "Ultrastructure, steroidogenic potential, and energy metabolism of the Snell adrenocortical carcinoma 494. A comparison with normal adrenocortical tissue. Electron microscope studies were carried out with the adrenocortical carcinoma 494 and normal adrenal cortex tissue. The mitochondria of the tumor cells showed marked differences when compared with mitochondria from fasciculata cells of the normal adrenal cortex. These differences were primarily related to mitochondrial number and crista structure. Corticosterone production in isolated tumor cells was extremely low and neither ACTH nor dibutyryl cyclic AMP had any stimulatory effect. Normal adrenal cells showed at least a tenfold increase under identical conditions. In the presence of corticosteroid precursors the amount of corticosterone produced by the tumor cells was much less than that produced by normal cells. The results indicate a reduced capacity for 11beta-hydroxylation in the tumor mitochondria and a possible reduced capacity for biosynthetic steps before the 11beta-hydroxylation reaction. Glycolysis in isolated tumor cells was also lower than in normal cells. Isolated tumor mitochondria oxidized succinate normally with a good degree of coupling with phosphorylation. However, unlike normal adrenal mitochondria, the tumor mitochondria showed little or no oxygen uptake with other Krebs cycle substrates. These data suggest that the tumor mitochondria may be lacking in the flavoprotein dehydrogenases responsible for the oxidation of NADH and NADPH, although other components of the respiratory chain may be intact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366105"}
{"pmid": "4366109", "title": "Time on organic evolution.", "content": "Time on organic evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366109"}
{"pmid": "4366104", "title": "Colchicine-induced inhibition of lipoprotein and protein secretion into the serum and lack of interference with secretion of biliary phospholipids and cholesterol by rat liver in vivo.", "content": "Colchicine-induced inhibition of lipoprotein and protein secretion into the serum and lack of interference with secretion of biliary phospholipids and cholesterol by rat liver in vivo. Rats were injected with colchicine and the secretion of triglycerides into the serum was studied for 90 min after injection of [(14)C]palmitic acid and Triton WR 1339. The release of labeled and chemically determined triglyceride was reduced to about 20-30% of control values. The effect of colchicine on serum triglyceride levels was not dependent on the presence of Triton and was similar in males and females and in fed and fasted rats. The effect was dose dependent and was reversible 6-7 h after injection of 0.05 mg/100 g body weight. Colchicine inhibited also the release of labeled proteins into the serum but did not affect the amount of [(3)H]leucine incorporated into liver proteins. Within 4 h of colchicine treatment there was an 80% fall in serum very low density lipoproteins (VLDL), a 30% fall in serum high density lipoproteins (HDL), and no change in the d > 1.21 protein level, but reduction in the appearance of labeled proteins was encountered in all serum fractions. Colchicine had no effect on the rate of bile flow and on the secretion of phospholipids and cholesterol into the bile. In the hepatocyte there was accumulation of Golgi-derived secretory vesicles, containing nascent VLDL particles; these vesicles were seen also in the vicinity of the sinusoidal cell surface, but the space of Disse contained few or no VLDL particles. There was an apparent reduction in microtubules and some increase in microfilaments. It is suggested that microtubules affect the secretion of lipoproteins and proteins into the serum by maintaining the organization of the plasma membrane required for its fusion with secretory vesicles. The lack of effect of colchicine on biliary lipid secretion indicates that the latter is not dependent on vesicular transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366104"}
{"pmid": "4366107", "title": "Effect of dibutyryl adenosine cyclic 3',5'-monophosphate and testololactone on concanavalin A binding and cell killing.", "content": "Effect of dibutyryl adenosine cyclic 3',5'-monophosphate and testololactone on concanavalin A binding and cell killing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366107"}
{"pmid": "4366097", "title": "Observations on the epidemiology of pseudocowpox in South-west England and South Wales.", "content": "Observations on the epidemiology of pseudocowpox in South-west England and South Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366097"}
{"pmid": "4366110", "title": "A study of the renin-angiotensin system in the nephrotic syndrome.", "content": "A study of the renin-angiotensin system in the nephrotic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366110"}
{"pmid": "4366111", "title": "The effect of intravenous oestrogen injections on plasma human placental lactogen levels.", "content": "The effect of intravenous oestrogen injections on plasma human placental lactogen levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366111"}
{"pmid": "4366112", "title": "Adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices: effect of benzodiazepines.", "content": "Adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices: effect of benzodiazepines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366112"}
{"pmid": "4366113", "title": "Alterations in cyclic AMP metabolism associated with photoreceptor cell degeneration in the C3H mouse.", "content": "Alterations in cyclic AMP metabolism associated with photoreceptor cell degeneration in the C3H mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366113"}
{"pmid": "4366114", "title": "Effects of ATP on the activity of nucleoside 3',5'-cyclic monophosphate phosphodiesterase from brain.", "content": "Effects of ATP on the activity of nucleoside 3',5'-cyclic monophosphate phosphodiesterase from brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366114"}
{"pmid": "4366115", "title": "Oat cell tumor of the small bowel.", "content": "Oat cell tumor of the small bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366115"}
{"pmid": "4366116", "title": "Corticotrophin-like peptides in the rat pituitary.", "content": "Corticotrophin-like peptides in the rat pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366116"}
{"pmid": "4366117", "title": "Purification and characterization of porcine corticotrophin-like intermediate lobe peptide.", "content": "Purification and characterization of porcine corticotrophin-like intermediate lobe peptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366117"}
{"pmid": "4366119", "title": "The thyrotrophin receptor in guinea-pig thyroid homogenate: general properties.", "content": "The thyrotrophin receptor in guinea-pig thyroid homogenate: general properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366119"}
{"pmid": "4366118", "title": "DNA synthesis and the secretion of prolactin and growth hormone by the pituitary gland of the male rat: effects of diethylstilboestrol and 2-bromo-alpha-ergocryptine methanesluphonate.", "content": "DNA synthesis and the secretion of prolactin and growth hormone by the pituitary gland of the male rat: effects of diethylstilboestrol and 2-bromo-alpha-ergocryptine methanesluphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366118"}
{"pmid": "4366120", "title": "The thyrotrophin receptor in guinea-pig thyroid homogenate: interaction with the long-acting thyroid stimulator.", "content": "The thyrotrophin receptor in guinea-pig thyroid homogenate: interaction with the long-acting thyroid stimulator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366120"}
{"pmid": "4366121", "title": "Genetic study of the effects of (8-arginine)- and (8-lysine)-vasopressins on adenyl cyclase activity of mouse kidney.", "content": "Genetic study of the effects of (8-arginine)- and (8-lysine)-vasopressins on adenyl cyclase activity of mouse kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366121"}
{"pmid": "4366124", "title": "Letter: Serological tests for amoebiasis.", "content": "Letter: Serological tests for amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366124"}
{"pmid": "4366122", "title": "Virological findings and blood gas tensions in acute lower respiratory tract infections in children.", "content": "Virological findings and blood gas tensions in acute lower respiratory tract infections in children. Sequential blood gas tensions and pH have been measured in 84 children selected from 486 admitted to hospital during a 15-month period with acute lower respiratory tract infections. Of those selected 73 were treated conservatively and 11 by intermittent positive-pressure ventilation; one infant in the latter group died. Respiratory syncytial virus (R.S.V.) was isolated from 24 out of 62 patients studied and the main pathogen in the most severely affected infants. Statistical analysis showed that age and R.S.V. infection were independent determinants of severity, as reflected by a peak Pco(2) measurement at the height of the illness (age, P < 0.01; R.S.V. 0.05 > P > 0.01).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366122"}
{"pmid": "4366123", "title": "Acute respiratory failure in bronchiolitis and pneumonia in infancy. Modes of presentation and treatment.", "content": "Acute respiratory failure in bronchiolitis and pneumonia in infancy. Modes of presentation and treatment. The modes of presentation and the management of acute respiratory failure in 11 infants with severe lower respiratory tract infections (due to respiratory syncytial virus in eight) are described. Progressive respiratory difficulties leading to exhaustion, peripheral circulatory collapse, recurrent apnoeic attacks, or generalized convulsions were the main clinical presentations resulting in severe ventilatory failure. In nine infants preventilation carbon dioxide tensions exceeded 65 mm Hg. It seems likely that the use of intermittent positive-pressure ventilation in these patients contributed to the low mortality rate, less than 0.5%, from such illnesses during the 15-month study period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366123"}
{"pmid": "4366125", "title": "Studies on hormone-cytostatic complexes in the cytoplasm of rat prostatic gland.", "content": "Studies on hormone-cytostatic complexes in the cytoplasm of rat prostatic gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366125"}
{"pmid": "4366126", "title": "Estracyt (NSC 89199) as a substrate for phosphatases in human serum.", "content": "Estracyt (NSC 89199) as a substrate for phosphatases in human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366126"}
{"pmid": "4366129", "title": "Immunology of virus-induced tumours.", "content": "Immunology of virus-induced tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366129"}
{"pmid": "4366128", "title": "Cellular hypersensitivity in Guillain-Barré syndrome.", "content": "Cellular hypersensitivity in Guillain-Barré syndrome. The Guillain-Barré syndrome is hypothesized to be secondary to cellular hypersensitivity to peripheral nerve antigens. To test this theory lymphocytes from 100 subjects were studied using the macrophage-migration-inhibition factor (MIF) assay. Thirty-four normal controls gave a mean migration of 100.4 +/- 9%. Of 34 patients with peripheral nervous system disease, only those with the Guillain-Barré syndrome showed hypersensitivity with a mean migration of 72 +/- 11%. Of 34 patients with central nervous system disease only three with multiple sclerosis and two with stroke gave similar results. Positive results in the Guillain-Barré syndrome were found only in patients presenting with classical disease and who were ill at the time of study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366128"}
{"pmid": "4366130", "title": "Oncogenic DNA viruses of nonhuman primates: a review.", "content": "Oncogenic DNA viruses of nonhuman primates: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366130"}
{"pmid": "4366132", "title": "Transvenous adrenal destruction: clinical trials in patients with metastatic malignancy.", "content": "Transvenous adrenal destruction: clinical trials in patients with metastatic malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366132"}
{"pmid": "4366133", "title": "A possible mechanism of 1,2-shift reactions catalyzed by coenzyme B 12 dependent enzymes.", "content": "A possible mechanism of 1,2-shift reactions catalyzed by coenzyme B 12 dependent enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366133"}
{"pmid": "4366134", "title": "The pharmacodynamics of depression and its relation to therapy.", "content": "The pharmacodynamics of depression and its relation to therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366134"}
{"pmid": "4366135", "title": "Beta-islet cell tumors of the pancreas: results of a study on 1,067 cases.", "content": "Beta-islet cell tumors of the pancreas: results of a study on 1,067 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366135"}
{"pmid": "4366136", "title": "Contributions of clonal systems to neurobiology.", "content": "Contributions of clonal systems to neurobiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366136"}
{"pmid": "4366144", "title": "Studies on the availability of intramitochondrial carbamoylphosphate for utilization in extramitochondrial reactions in rat liver.", "content": "Studies on the availability of intramitochondrial carbamoylphosphate for utilization in extramitochondrial reactions in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366144"}
{"pmid": "4366145", "title": "Cytochrome c interaction with membranes. Interaction of cytochrome c with isolated membrane fragments and purified enzymes.", "content": "Cytochrome c interaction with membranes. Interaction of cytochrome c with isolated membrane fragments and purified enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366145"}
{"pmid": "4366146", "title": "Effects of membrane steroid modification on human erythrocyte glucose transport.", "content": "Effects of membrane steroid modification on human erythrocyte glucose transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366146"}
{"pmid": "4366147", "title": "On the interpretation of electron paramagnetic resonance spectra of binuclear iron-sulfur proteins.", "content": "On the interpretation of electron paramagnetic resonance spectra of binuclear iron-sulfur proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366147"}
{"pmid": "4366148", "title": "Stimulation of cytochrome synthesis in Escherichia coli by cyclic AMP.", "content": "Stimulation of cytochrome synthesis in Escherichia coli by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366148"}
{"pmid": "4366149", "title": "Polyacrylamide gel electrophoresis of glycoproteins on single concentration and gradient gels.", "content": "Polyacrylamide gel electrophoresis of glycoproteins on single concentration and gradient gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366149"}
{"pmid": "4366150", "title": "Resonance-raman evidence for anomalous heme structures in cytochrome c' from Rhodopseudomonas palustris.", "content": "Resonance-raman evidence for anomalous heme structures in cytochrome c' from Rhodopseudomonas palustris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366150"}
{"pmid": "4366151", "title": "Purification and properties of a protein which stimulates succinate oxidation in the particulate fraction of Azotobacter vinelandii.", "content": "Purification and properties of a protein which stimulates succinate oxidation in the particulate fraction of Azotobacter vinelandii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366151"}
{"pmid": "4366152", "title": "Localization of low-density lipoproteins in atherosclerotic lesions from human normolipemics employing a purified fluorescent-labeled antibody.", "content": "Localization of low-density lipoproteins in atherosclerotic lesions from human normolipemics employing a purified fluorescent-labeled antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366152"}
{"pmid": "4366154", "title": "Energy-dependent accumulation of iron by isolated rat liver mitochondria. 3. Submitochondrial localization of the iron accumulated.", "content": "Energy-dependent accumulation of iron by isolated rat liver mitochondria. 3. Submitochondrial localization of the iron accumulated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366154"}
{"pmid": "4366155", "title": "Biochemical and biophysical studies on cytochrome c oxidase. XVI. Circular dichroic study of cytochrome c oxidase and its ligand complexes.", "content": "Biochemical and biophysical studies on cytochrome c oxidase. XVI. Circular dichroic study of cytochrome c oxidase and its ligand complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366155"}
{"pmid": "4366157", "title": "Synaptic potentials of hypoglossal motoneurons and a common inhibitory interneuron in the trigemino-hypoglossal reflex.", "content": "Synaptic potentials of hypoglossal motoneurons and a common inhibitory interneuron in the trigemino-hypoglossal reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366157"}
{"pmid": "4366156", "title": "Articular rhizotomy.", "content": "Articular rhizotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366156"}
{"pmid": "4366158", "title": "The accumulation of adenosine 3',5'-monophosphate in cerebral cortical slices of the quaking mouse, a neurologic mutant.", "content": "The accumulation of adenosine 3',5'-monophosphate in cerebral cortical slices of the quaking mouse, a neurologic mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366158"}
{"pmid": "4366159", "title": "Biochemical and physiological properties of a purified snake venom neurotoxin which acts presynaptically.", "content": "Biochemical and physiological properties of a purified snake venom neurotoxin which acts presynaptically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366159"}
{"pmid": "4366160", "title": "Characterization of the serum low-density lipoproteins of normal and two rhesus monkeys with spontaneous hyperbeta-lipoproteinemia.", "content": "Characterization of the serum low-density lipoproteins of normal and two rhesus monkeys with spontaneous hyperbeta-lipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366160"}
{"pmid": "4366165", "title": "Alcohol dehydrogenases of Euglena gracilis, strain Z.", "content": "Alcohol dehydrogenases of Euglena gracilis, strain Z.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366165"}
{"pmid": "4366166", "title": "A DNA antigen that reacts with antisera to cardiolipin.", "content": "A DNA antigen that reacts with antisera to cardiolipin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366166"}
{"pmid": "4366164", "title": "Cyclic AMP stimulation of calcium efflux from kidney, liver and heart mitochondria.", "content": "Cyclic AMP stimulation of calcium efflux from kidney, liver and heart mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366164"}
{"pmid": "4366168", "title": "Liver microsomal electron transport systems. II. The involvement of cytochrome b5 in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted cytochrome P-448-containing system.", "content": "Liver microsomal electron transport systems. II. The involvement of cytochrome b5 in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted cytochrome P-448-containing system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366168"}
{"pmid": "4366167", "title": "Singlet oxygen generation by the lipoxidase system.", "content": "Singlet oxygen generation by the lipoxidase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366167"}
{"pmid": "4366172", "title": "Effect of nuclear protein kinases on mammalian RNA synthesis.", "content": "Effect of nuclear protein kinases on mammalian RNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366172"}
{"pmid": "4366176", "title": "Proceedings: Effects of hypoxia on maternal and foetal renin and angiotensin II in sheep.", "content": "Proceedings: Effects of hypoxia on maternal and foetal renin and angiotensin II in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366176"}
{"pmid": "4366175", "title": "Proceedings: Peptide antagonists of the renin-angiotensin system and the elucidation of the receptors for angiotensin-induced drinking.", "content": "Proceedings: Peptide antagonists of the renin-angiotensin system and the elucidation of the receptors for angiotensin-induced drinking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366175"}
{"pmid": "4366174", "title": "Use of (1-14C) aectic anhydride to quantitate diglycerides: a new analytical procedure.", "content": "Use of (1-14C) aectic anhydride to quantitate diglycerides: a new analytical procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366174"}
{"pmid": "4366178", "title": "The muscular atrophy of central origin (an ultramicroscopic study on muscle biopsy material).", "content": "The muscular atrophy of central origin (an ultramicroscopic study on muscle biopsy material).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366178"}
{"pmid": "4366177", "title": "The amino-acid sequence of sarcine adenylate kinase from skeletal muscle.", "content": "The amino-acid sequence of sarcine adenylate kinase from skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366177"}
{"pmid": "4366180", "title": "Positive and negative control of bacterial gene expression.", "content": "Positive and negative control of bacterial gene expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366180"}
{"pmid": "4366181", "title": "A prospective controlled study of neonatal hypoglycemia.", "content": "A prospective controlled study of neonatal hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366181"}
{"pmid": "4366183", "title": "Performances of Mueller-Hinton agars prepared by three manufacturers.", "content": "Performances of Mueller-Hinton agars prepared by three manufacturers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366183"}
{"pmid": "4366184", "title": "Role of the superoxide anion in the myeloperoxidase-mediated antimicrobial system.", "content": "Role of the superoxide anion in the myeloperoxidase-mediated antimicrobial system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366184"}
{"pmid": "4366185", "title": "Proceedings: Physiology and enzymology of frog photoreceptor membranes.", "content": "Proceedings: Physiology and enzymology of frog photoreceptor membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366185"}
{"pmid": "4366186", "title": "Proceedings: Light regulation of adenosine 3',5' cyclic monophosphate levels in vertebrate photoreceptors.", "content": "Proceedings: Light regulation of adenosine 3',5' cyclic monophosphate levels in vertebrate photoreceptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366186"}
{"pmid": "4366187", "title": "A new overgrowth syndrome with accelerated skeletal maturation, unusual facies, and camptodactyly.", "content": "A new overgrowth syndrome with accelerated skeletal maturation, unusual facies, and camptodactyly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366187"}
{"pmid": "4366188", "title": "Lipoproteins in neonates.", "content": "Lipoproteins in neonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366188"}
{"pmid": "4366189", "title": "The effects of acetylcholine and of synaptic stimulation on the sensorimotor cortex of cats. I. Neuronal responses to stimulation of the reticular formation.", "content": "The effects of acetylcholine and of synaptic stimulation on the sensorimotor cortex of cats. I. Neuronal responses to stimulation of the reticular formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366189"}
{"pmid": "4366190", "title": "Biochemically active substances from Actinomycetes and other organisms. II. Effects of various compounds on motilometry.", "content": "Biochemically active substances from Actinomycetes and other organisms. II. Effects of various compounds on motilometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366190"}
{"pmid": "4366191", "title": "Dissociated loss of cold and warm sensibility during regional anaesthesia.", "content": "Dissociated loss of cold and warm sensibility during regional anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366191"}
{"pmid": "4366193", "title": "Fine structure of Bowen's disease in chronic arsenicalism.", "content": "Fine structure of Bowen's disease in chronic arsenicalism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366193"}
{"pmid": "4366194", "title": "Effects of cis-dichlorodiammine platinum (II) in the regression of sarcoma 180: a fine structural study.", "content": "Effects of cis-dichlorodiammine platinum (II) in the regression of sarcoma 180: a fine structural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366194"}
{"pmid": "4366195", "title": "Humoral immune responses to tumor-specific antigens in strain-2 guinea pigs.", "content": "Humoral immune responses to tumor-specific antigens in strain-2 guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366195"}
{"pmid": "4366197", "title": "Summary and recommendations of the workshop on uterine-cervical cancer.", "content": "Summary and recommendations of the workshop on uterine-cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366197"}
{"pmid": "4366196", "title": "Epithelial cell cultures from normal glandular tissue of mice.", "content": "Epithelial cell cultures from normal glandular tissue of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366196"}
{"pmid": "4366198", "title": "Respiratory virus inhibitors in the colostrum of Chinese donors.", "content": "Respiratory virus inhibitors in the colostrum of Chinese donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366198"}
{"pmid": "4366199", "title": "Effects of corticotrophin, starvation and glucose on ascorbic acid levels in the blood plasma and liver of piglets.", "content": "Effects of corticotrophin, starvation and glucose on ascorbic acid levels in the blood plasma and liver of piglets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366199"}
{"pmid": "4366200", "title": "Lack of fixed order of recruitment in cat motoneuron pools.", "content": "Lack of fixed order of recruitment in cat motoneuron pools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366200"}
{"pmid": "4366201", "title": "Purification of alpha-toxin (phospholipase C) of Clostridium perfringens by affinity chromatography.", "content": "Purification of alpha-toxin (phospholipase C) of Clostridium perfringens by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366201"}
{"pmid": "4366202", "title": "Fine structure of myogenesis and elastogenesis in the developing rat lung.", "content": "Fine structure of myogenesis and elastogenesis in the developing rat lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366202"}
{"pmid": "4366203", "title": "A colicin-tolerant mutant of Escherichia coli with reduced levels of cyclic AMP and the regulation of lambdoid phage lysogeny.", "content": "A colicin-tolerant mutant of Escherichia coli with reduced levels of cyclic AMP and the regulation of lambdoid phage lysogeny.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366203"}
{"pmid": "4366205", "title": "Spin-label studies at F9(93)beta of deoxyhemoglobin S aggregation.", "content": "Spin-label studies at F9(93)beta of deoxyhemoglobin S aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366205"}
{"pmid": "4366206", "title": "Brenner tumors and Walthard cell nests.", "content": "Brenner tumors and Walthard cell nests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366206"}
{"pmid": "4366207", "title": "Atherosclerosis in rat kangaroos.", "content": "Atherosclerosis in rat kangaroos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366207"}
{"pmid": "4366209", "title": "Proteinaceous hexagonal inclusions in hyphae of Whetzelinia sclerotiorum and Neurospora crassa.", "content": "Proteinaceous hexagonal inclusions in hyphae of Whetzelinia sclerotiorum and Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366209"}
{"pmid": "4366211", "title": "Influence of mesencephalic stimulation on unit activity in striate cortex of squirrel monkeys.", "content": "Influence of mesencephalic stimulation on unit activity in striate cortex of squirrel monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366211"}
{"pmid": "4366213", "title": "A supraspinal monosynaptic input to hindlimb motoneurons in lumbar spinal cord of the frog, Rana catesbiana.", "content": "A supraspinal monosynaptic input to hindlimb motoneurons in lumbar spinal cord of the frog, Rana catesbiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366213"}
{"pmid": "4366212", "title": "Dynamic characteristics of responses to horizontal head angular acceleration in vestibuloocular pathway in the cat.", "content": "Dynamic characteristics of responses to horizontal head angular acceleration in vestibuloocular pathway in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366212"}
{"pmid": "4366215", "title": "Phenylethanolamine-N-methyl transferase activity in the avian adrenal following immobilization or adrenocorticotropin.", "content": "Phenylethanolamine-N-methyl transferase activity in the avian adrenal following immobilization or adrenocorticotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366215"}
{"pmid": "4366216", "title": "Transformation by adenovirus type 12 of rat embryol fibroblasts cultivated in the presence of interferon.", "content": "Transformation by adenovirus type 12 of rat embryol fibroblasts cultivated in the presence of interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366216"}
{"pmid": "4366217", "title": "Bacterial pathogens in dry dog foods.", "content": "Bacterial pathogens in dry dog foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366217"}
{"pmid": "4366219", "title": "Alterations with age in composition and lipolytic activity of adipose tissue from male and female chickens.", "content": "Alterations with age in composition and lipolytic activity of adipose tissue from male and female chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366219"}
{"pmid": "4366218", "title": "Abnormality in hepatic lipids of a patient having taken coralgil, (hexestrol bis (beta-diethylaminoethyl ether)) for a long period.", "content": "Abnormality in hepatic lipids of a patient having taken coralgil, (hexestrol bis (beta-diethylaminoethyl ether)) for a long period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366218"}
{"pmid": "4366221", "title": "The effect of ergocornine on melanophores of Ambystoma tigrinum: evidence for suppression of pituitary MSH release.", "content": "The effect of ergocornine on melanophores of Ambystoma tigrinum: evidence for suppression of pituitary MSH release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366221"}
{"pmid": "4366223", "title": "Gas chromatographic resolution of homologous monoacyl and monoalkylglycerols.", "content": "Gas chromatographic resolution of homologous monoacyl and monoalkylglycerols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366223"}
{"pmid": "4366222", "title": "Subcutaneous glucagon as a test of the ability of the pituitary to secrete GH and ACTH.", "content": "Subcutaneous glucagon as a test of the ability of the pituitary to secrete GH and ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366222"}
{"pmid": "4366224", "title": "Biosynthesis of monoacyl-sn-glycerol 3-phosphate by rabbit heart mitochondria: positional specificity differing from liver enzyme.", "content": "Biosynthesis of monoacyl-sn-glycerol 3-phosphate by rabbit heart mitochondria: positional specificity differing from liver enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366224"}
{"pmid": "4366225", "title": "Prostaglandins of rat testis.", "content": "Prostaglandins of rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366225"}
{"pmid": "4366227", "title": "Embryonic vs tumor lipids. II. Changes in phospholipids of developing chick brain, heart, and liver.", "content": "Embryonic vs tumor lipids. II. Changes in phospholipids of developing chick brain, heart, and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366227"}
{"pmid": "4366228", "title": "The ACTH-enhanced conversion of 118-hydroxyprogesterone to corticosterone in the adrenal glands of fetal rhesus monkeys (Macaca mulatta).", "content": "The ACTH-enhanced conversion of 118-hydroxyprogesterone to corticosterone in the adrenal glands of fetal rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366228"}
{"pmid": "4366226", "title": "In vivo and in vitro biosynthesis of free fatty alcohols in Escherichia coli K-12.", "content": "In vivo and in vitro biosynthesis of free fatty alcohols in Escherichia coli K-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366226"}
{"pmid": "4366229", "title": "Gas chromatographic differentiation of 4-desmethyl, 4-monomethyl and 4,4-dimethylsterols.", "content": "Gas chromatographic differentiation of 4-desmethyl, 4-monomethyl and 4,4-dimethylsterols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366229"}
{"pmid": "4366230", "title": "Simultaneous radioimmunoassay of testosterone and dihydrotestosterone.", "content": "Simultaneous radioimmunoassay of testosterone and dihydrotestosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366230"}
{"pmid": "4366231", "title": "Extranasopharyngeal juvenile angiofibroma--a case report.", "content": "Extranasopharyngeal juvenile angiofibroma--a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366231"}
{"pmid": "4366232", "title": "Plasticity in small neuronal assemblies.", "content": "Plasticity in small neuronal assemblies. When spike activity of two or more individual neurons is simultaneously recorded, it is possible to detect various types of neuronal connections to and between the observed neurons by making appropriate statistical analysis of the data. Such methods are reviewed. This approach is particularly useful in seeking changes of neuronal connectivity associated with behavioral plasticity. Examples from experiments with Aplysia and crayfish are given.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366232"}
{"pmid": "4366234", "title": "Influence of pure virus infection on wound healing.", "content": "Influence of pure virus infection on wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366234"}
{"pmid": "4366235", "title": "Insulin responses to calcium infusion.", "content": "Insulin responses to calcium infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366235"}
{"pmid": "4366233", "title": "The role of the renin-angiotensin system in the aldosterone response to acute hemorrhage.", "content": "The role of the renin-angiotensin system in the aldosterone response to acute hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366233"}
{"pmid": "4366236", "title": "Alterations in plasma aldosterone levels in response to acute stimuli in kidney allograft recipients.", "content": "Alterations in plasma aldosterone levels in response to acute stimuli in kidney allograft recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366236"}
{"pmid": "4366237", "title": "Influence of altered cyclic 3',5'-adenosine monophosphate phosphodiesterase activity on systemic hemodynamics.", "content": "Influence of altered cyclic 3',5'-adenosine monophosphate phosphodiesterase activity on systemic hemodynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366237"}
{"pmid": "4366238", "title": "Diagnosis of pulmonary cytomegalic virus by bronchoscopy.", "content": "Diagnosis of pulmonary cytomegalic virus by bronchoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366238"}
{"pmid": "4366240", "title": "Temperature-sensitive mutations in Habrobracon.", "content": "Temperature-sensitive mutations in Habrobracon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366240"}
{"pmid": "4366239", "title": "Histamine and collagen synthesis in keloid and hypertrophic scar.", "content": "Histamine and collagen synthesis in keloid and hypertrophic scar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366239"}
{"pmid": "4366241", "title": "The regulation of NAD L-glutamate dehydrogenase in Aspergillus nidulans.", "content": "The regulation of NAD L-glutamate dehydrogenase in Aspergillus nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366241"}
{"pmid": "4366242", "title": "Differentiation between the steroidogenic effects of cholera enterotoxin and adrenocorticotropin through use of a mutant adrenal cell line.", "content": "Differentiation between the steroidogenic effects of cholera enterotoxin and adrenocorticotropin through use of a mutant adrenal cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366242"}
{"pmid": "4366244", "title": "Demonstration of acetylcholine-sensitive adenyl cyclase in malignant neuroblastoma cells in culutre.", "content": "Demonstration of acetylcholine-sensitive adenyl cyclase in malignant neuroblastoma cells in culutre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366244"}
{"pmid": "4366243", "title": "Yeast glycogen synthetase in the glucose 6-phosphate-dependent form. II. The effect of proteolysis.", "content": "Yeast glycogen synthetase in the glucose 6-phosphate-dependent form. II. The effect of proteolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366243"}
{"pmid": "4366246", "title": "Hydroxyproline in the early diagnosis of bone metastases in prostatic cancer.", "content": "Hydroxyproline in the early diagnosis of bone metastases in prostatic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366246"}
{"pmid": "4366247", "title": "Letter: Ménétrier disease.", "content": "Letter: Ménétrier disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366247"}
{"pmid": "4366245", "title": "Effects of phorbol myristate acetate on the metabolism and ultrastructure of neutrophils in chronic granulomatous disease.", "content": "Effects of phorbol myristate acetate on the metabolism and ultrastructure of neutrophils in chronic granulomatous disease. Previous investigations have demonstrated that phorbol myristate acetate (PMA), the active principle of croton oil, stimulates alterations in normal polymorphonuclear leukocytes (PMN) that resemble closely the changes that develop in the cells after phagocytosis of bacteria. The present study has compared the effects of PMA and heat-killed bacteria on the oxygen uptake, glucose oxidation, nitroblue tetrazolium (NBT) reduction, and ultrastructure of normal neutrophils and PMN from six patients with chronic granulomatous disease (CGD). PMA stimulated oxygen consumption, hexose monophosphate shunt activity, and NBT reduction in normal cells but failed to produce similar effects in CGD neutrophils. However, PMA did induce formation of cytoplasmic vacuoles in the CGD cells similar to those observed in normal neutrophils. The results indicate that PMA is a useful nonparticulate agent for distinguishing between normal and CGD neutrophils and for studying basic mechanisms of phagocytosis in normal and abnormal PMN.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366245"}
{"pmid": "4366248", "title": "Sensitivity of serological tests and the diagnosis of streptococcal sore throat in children.", "content": "Sensitivity of serological tests and the diagnosis of streptococcal sore throat in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366248"}
{"pmid": "4366249", "title": "Proceedings: Renin and lysosomal enzyme activities in the kidney of spontaneously hypertensive rats.", "content": "Proceedings: Renin and lysosomal enzyme activities in the kidney of spontaneously hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366249"}
{"pmid": "4366250", "title": "Regulation of glycerol catabolism in Klebsiella aerogenes.", "content": "Regulation of glycerol catabolism in Klebsiella aerogenes. The utilization of glycerol as a carbon source for growth by Klebsiella aerogenes, strain 2103, involves separate aerobic (sn-glycerol-3-phosphate or G3P) and anaerobic (dihydroxyacetone or DHA) pathways of catabolism. Enzyme and transport activities of the aerobic pathway are elevated in cells grown under oxygenated conditions on glycerol or G3P. Anaerobic growth on G3P as carbon source requires the presence of an exogenous hydrogen acceptor such as fumarate; cells thus grown also are highly induced in the G3P pathway. Anaerobic growth on glycerol requires no exogenous hydrogen acceptors; cells thus grown are highly induced in the DHA pathway but almost uninduced in the G3P pathway and the addition of fumarate electron acceptors has no effect on the relative levels of the two pathways. When both glycerol and G3P are provided anaerobically with fumarate, the DHA pathway is still preferentially induced, which probably accounts for the exclusive utilization of glycerol until its exhaustion. These observations suggest the presence of a regulatory control of G3P pathway imposed by the operation of the DHA pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366250"}
{"pmid": "4366251", "title": "Evidence for a composite state of an F'his, gnd element and a cryptic plasmid in a derivative of Salmonella typhimurium LT2.", "content": "Evidence for a composite state of an F'his, gnd element and a cryptic plasmid in a derivative of Salmonella typhimurium LT2. A method designed to select mutants constitutive for expression of the histidine operon has been applied to a Salmonella typhimurium LT2 strain containing an F'his,gnd element and a cryptic plasmid. One of the mutants isolated, strain AA0019, has not only increased levels of histidinol phosphate phosphatase (hisB), but also increased levels of gluconate-6-phosphate dehydrogenase (gnd). Ultracentrifugation studies of extrachromosomal deoxyribonucleic acid (DNA) isolated from strain AA0019 revealed the presence of a single species of covalently closed circular (CCC) DNA that sedimented more rapidly through neutral and alkaline sucrose gradients than any of its possible plasmid precursors. From neutral sucrose gradients, sedimentation coefficients of 130, 100, and 86S were derived, corresponding to the CCC DNA of the large plasmid in strain AA0019, the F'his,gnd element and the cryptic LT2 plasmid, respectively. An Escherichia coli plasmid-free strain that upon mating had received the large 130S plasmid also contained 86S and 100S CCC DNA components. A histidine-requiring derivative of strain AA0019 obtained after acridine orange treatment retained the cryptic plasmid DNA. Apparently, the large plasmid in strain AA0019 consists of the F'his,gnd element and the cryptic LT2 plasmid of the parental strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366251"}
{"pmid": "4366252", "title": "Differential diagnosis of an abnormal brain scan.", "content": "Differential diagnosis of an abnormal brain scan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366252"}
{"pmid": "4366254", "title": "Papillary cystadenoma lymphomatosum associated with pleomorphic adenoma of the parotid gland.", "content": "Papillary cystadenoma lymphomatosum associated with pleomorphic adenoma of the parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366254"}
{"pmid": "4366259", "title": "Reusability of silica gel in thin layer chromatography.", "content": "Reusability of silica gel in thin layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366259"}
{"pmid": "4366260", "title": "The effects of human serum on local (Ibadan) strains of Entamoeba histolytica. (Preliminary studies).", "content": "The effects of human serum on local (Ibadan) strains of Entamoeba histolytica. (Preliminary studies).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366260"}
{"pmid": "4366261", "title": "Proceedings: Long-term follow-up of fluorine-18 bone scans in carcinoma of the prostate.", "content": "Proceedings: Long-term follow-up of fluorine-18 bone scans in carcinoma of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366261"}
{"pmid": "4366262", "title": "Proceedings: Urinary hydroxyproline and leucocyte ascorbic acid levels in patients bearing breast tumour with skeletal metastases.", "content": "Proceedings: Urinary hydroxyproline and leucocyte ascorbic acid levels in patients bearing breast tumour with skeletal metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366262"}
{"pmid": "4366263", "title": "Studies on a new antiviral antibiotic, 9-methylstreptimidone. I. Physicochemical and biological properties.", "content": "Studies on a new antiviral antibiotic, 9-methylstreptimidone. I. Physicochemical and biological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366263"}
{"pmid": "4366255", "title": "Juvenile nasopharyngeal angiofibroma.", "content": "Juvenile nasopharyngeal angiofibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366255"}
{"pmid": "4366267", "title": "Formation of interchain disulfide bonds and helical structure during biosynthesis of procollagen by embryonic tendon cells.", "content": "Formation of interchain disulfide bonds and helical structure during biosynthesis of procollagen by embryonic tendon cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366267"}
{"pmid": "4366268", "title": "Comparison of proteins of ribosomal subunits and nucleolar preribosomal particles from Novikoff hepatoma ascites cells by two-dimensional polyacrylamide gel electrophoresis.", "content": "Comparison of proteins of ribosomal subunits and nucleolar preribosomal particles from Novikoff hepatoma ascites cells by two-dimensional polyacrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366268"}
{"pmid": "4366269", "title": "An electrophoretic method for the quantitative isolation of human and swine plasma lipoproteins.", "content": "An electrophoretic method for the quantitative isolation of human and swine plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366269"}
{"pmid": "4366270", "title": "Wilms' tumor.", "content": "Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366270"}
{"pmid": "4366265", "title": "Adrenergic receptors and insulin secretion.", "content": "Adrenergic receptors and insulin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366265"}
{"pmid": "4366283", "title": "Fat absorption after infusing bile salts into the human small intestine.", "content": "Fat absorption after infusing bile salts into the human small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366283"}
{"pmid": "4366284", "title": "Electron microscopy of small intestinal mucosa in pancreatic insufficiency.", "content": "Electron microscopy of small intestinal mucosa in pancreatic insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366284"}
{"pmid": "4366285", "title": "Jejunal calcium transport in health and metabolic bone disease: Effect of vitamin D.", "content": "Jejunal calcium transport in health and metabolic bone disease: Effect of vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366285"}
{"pmid": "4366286", "title": "Changes in the fine structure of mouse gastric epithelium produced by ethanol and urea.", "content": "Changes in the fine structure of mouse gastric epithelium produced by ethanol and urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366286"}
{"pmid": "4366287", "title": "Pathogenesis of herpetic encephalitis in mice after ophthalmic inoculation.", "content": "Pathogenesis of herpetic encephalitis in mice after ophthalmic inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366287"}
{"pmid": "4366289", "title": "News. From the National Academy of Sciences: Nomenclature of antigens associated with viral hepatitis type B.", "content": "News. From the National Academy of Sciences: Nomenclature of antigens associated with viral hepatitis type B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366289"}
{"pmid": "4366288", "title": "Effect of adenine arabinoside on cytomegalovirus infections.", "content": "Effect of adenine arabinoside on cytomegalovirus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366288"}
{"pmid": "4366290", "title": "Hyperoxia and lung metabolism.", "content": "Hyperoxia and lung metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366290"}
{"pmid": "4366291", "title": "Clinical trial design in studies of corticosteroids for bacterial infections.", "content": "Clinical trial design in studies of corticosteroids for bacterial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366291"}
{"pmid": "4366292", "title": "Letter: Anticoagulant therapy and acute adrenal insufficiency.", "content": "Letter: Anticoagulant therapy and acute adrenal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366292"}
{"pmid": "4366282", "title": "Viral disease of the labyrinth. I. Review of the literature and discussion of the role of cytomegalovirus in congenital deafness.", "content": "Viral disease of the labyrinth. I. Review of the literature and discussion of the role of cytomegalovirus in congenital deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366282"}
{"pmid": "4366293", "title": "Letter: Androgen role in erythroleukemia after treatment with alkylating agents.", "content": "Letter: Androgen role in erythroleukemia after treatment with alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366293"}
{"pmid": "4366294", "title": "Use of amoxicillin in the treatment of patients with septic abortion.", "content": "Use of amoxicillin in the treatment of patients with septic abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366294"}
{"pmid": "4366296", "title": "Ribonuclease T1 catalyzed degradation of transfer RNA: an unusual alteration induced by urea.", "content": "Ribonuclease T1 catalyzed degradation of transfer RNA: an unusual alteration induced by urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366296"}
{"pmid": "4366295", "title": "The frog dorsal column nucleus.", "content": "The frog dorsal column nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366295"}
{"pmid": "4366297", "title": "Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme.", "content": "Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366297"}
{"pmid": "4366299", "title": "A theoretical treatment of the turnover of protein-bound phosphate in the presence of both protein kinase and phosphatase activities.", "content": "A theoretical treatment of the turnover of protein-bound phosphate in the presence of both protein kinase and phosphatase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366299"}
{"pmid": "4366300", "title": "The effect of hypophysial hormones and human chorionic gonadotrophin (HCG) on the anencephalic fetal adrenal cortex and on parturition in the human.", "content": "The effect of hypophysial hormones and human chorionic gonadotrophin (HCG) on the anencephalic fetal adrenal cortex and on parturition in the human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366300"}
{"pmid": "4366301", "title": "Uptake and relase of (14C)adenine derivatives at beds of mammalian cortical synaptosomes in a superfusion system.", "content": "Uptake and relase of (14C)adenine derivatives at beds of mammalian cortical synaptosomes in a superfusion system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366301"}
{"pmid": "4366302", "title": "Transfer RNA and the regulation of protein synthesis in rat cerebral cortex during neural development.", "content": "Transfer RNA and the regulation of protein synthesis in rat cerebral cortex during neural development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366302"}
{"pmid": "4366303", "title": "Comparison of effects of long-term corticotrophin and corticosteroid treatment on responses of plasma growth hormone, ACTH, and corticosteroid to hypoglycaemia.", "content": "Comparison of effects of long-term corticotrophin and corticosteroid treatment on responses of plasma growth hormone, ACTH, and corticosteroid to hypoglycaemia. The development of the highly sensitive cytochemical bioassay for ACTH has permitted the measurement of plasma ACTH levels during the insulin hypoglycaemia test (I.H.T.) in patients treated with corticosteroids and corticotrophin. The ACTH, corticosteroid, and growth hormone (GH) responses in the I.H.T. were measured in three groups of 12 rheumatoid arthritis patients. One group was receiving long-term corticotrophin treatment, the second was undergoing long-term corticosteroid treatment, and the third had never received systemic hormone therapy. The increments in plasma ACTH, corticosteroids, and GH were diminished in the corticosteroid-treated group, as were increments in plasma GH and ACTH in the corticotrophin-treated group; but in this group the corticosteroid increment was normal. Examination of the area under the curve of the ACTH response showed that the total amount of ACTH secreted was normal though the rate of secretion was reduced. In the corticosteroid-treated group both rate and total secretion were diminished.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366303"}
{"pmid": "4366305", "title": "Methods for selecting and studying temperature-sensitive mutants of BHK-21 cells.", "content": "Methods for selecting and studying temperature-sensitive mutants of BHK-21 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366305"}
{"pmid": "4366306", "title": "Reversal of bacteriophage T4 induced polynucleotide kinase action.", "content": "Reversal of bacteriophage T4 induced polynucleotide kinase action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366306"}
{"pmid": "4366307", "title": "The catecholamines and aggressive behavior.", "content": "The catecholamines and aggressive behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366307"}
{"pmid": "4366309", "title": "Experimental herpes infection in the newborn rat. 3. Disease development after oral inoculation.", "content": "Experimental herpes infection in the newborn rat. 3. Disease development after oral inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366309"}
{"pmid": "4366310", "title": "Conjunctival collagenase: partial purification.", "content": "Conjunctival collagenase: partial purification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366310"}
{"pmid": "4366311", "title": "The pathogenesis of the neuropathy in dimorphous leprosy: electron microscopic and cytochemical studies.", "content": "The pathogenesis of the neuropathy in dimorphous leprosy: electron microscopic and cytochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366311"}
{"pmid": "4366312", "title": "Thyrotrophin responses to intravenous thyrotrophin-releasing hormone in patients with hypothalamic and pituitary disease.", "content": "Thyrotrophin responses to intravenous thyrotrophin-releasing hormone in patients with hypothalamic and pituitary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366312"}
{"pmid": "4366314", "title": "Glycerolipid formation from sn-glycerol-3-phosphate by rat liver cell fractions. The role of phosphatidate phosphohydrolase.", "content": "Glycerolipid formation from sn-glycerol-3-phosphate by rat liver cell fractions. The role of phosphatidate phosphohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366314"}
{"pmid": "4366313", "title": "31P nuclear magnetic resonance: application to the study of human serum high density lipoproteins.", "content": "31P nuclear magnetic resonance: application to the study of human serum high density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366313"}
{"pmid": "4366316", "title": "Effect of exogenous adenosine cyclic 3'-5'-monophosphate on antibody-producing cells in vivo and in vitro.", "content": "Effect of exogenous adenosine cyclic 3'-5'-monophosphate on antibody-producing cells in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366316"}
{"pmid": "4366315", "title": "An enzymatic explanation for dietary induced alterations in hepatic glycerolipid metabolism.", "content": "An enzymatic explanation for dietary induced alterations in hepatic glycerolipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366315"}
{"pmid": "4366319", "title": "Transcription products synthesized by purified calf thymus DNA-dependent RNA polymerase on Shope papilloma virus DNA.", "content": "Transcription products synthesized by purified calf thymus DNA-dependent RNA polymerase on Shope papilloma virus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366319"}
{"pmid": "4366320", "title": "Virus-like particles in human laryngeal papilloma. An ultrastructural study.", "content": "Virus-like particles in human laryngeal papilloma. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366320"}
{"pmid": "4366322", "title": "The efficacy of various mutagens and polyene antibiotics for the induction and isolation of sterol mutants of Neurospora crassa.", "content": "The efficacy of various mutagens and polyene antibiotics for the induction and isolation of sterol mutants of Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366322"}
{"pmid": "4366325", "title": "Chemical induction of streptomycin-resistant mutations in Escherichia coli. Dose and mutagenic effects of dichlorvos and methyl methanesulfonate.", "content": "Chemical induction of streptomycin-resistant mutations in Escherichia coli. Dose and mutagenic effects of dichlorvos and methyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366325"}
{"pmid": "4366324", "title": "Methionine biosynthesis in Saccharomyces cerevisiae: mutations at the regulatory locus ETH2. I. Genetic data.", "content": "Methionine biosynthesis in Saccharomyces cerevisiae: mutations at the regulatory locus ETH2. I. Genetic data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366324"}
{"pmid": "4366323", "title": "Rsf mutants of Escherichia coli HfrC defective in the production of the factor stimulating recombination in conjugation.", "content": "Rsf mutants of Escherichia coli HfrC defective in the production of the factor stimulating recombination in conjugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366323"}
{"pmid": "4366326", "title": "Repair replication and unscheduled DNA synthesis in mammalian cell lines showing differential sensitivity to alkylating agents.", "content": "Repair replication and unscheduled DNA synthesis in mammalian cell lines showing differential sensitivity to alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366326"}
{"pmid": "4366328", "title": "The molecular biology of the steroid hormones.", "content": "The molecular biology of the steroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366328"}
{"pmid": "4366331", "title": "Effect of prostaglandin E1 on hepatic cyclic AMP activity, carbohydrate and lipid metabolism.", "content": "Effect of prostaglandin E1 on hepatic cyclic AMP activity, carbohydrate and lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366331"}
{"pmid": "4366329", "title": "Effects of oestradiol on different cell types.", "content": "Effects of oestradiol on different cell types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366329"}
{"pmid": "4366330", "title": "Sequential gene expression in response to estradiol-17 beta during post-natal development of rat uterus.", "content": "Sequential gene expression in response to estradiol-17 beta during post-natal development of rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366330"}
{"pmid": "4366332", "title": "The relationship of transmitter release and storage to fine structure in a sympathetic ganglion.", "content": "The relationship of transmitter release and storage to fine structure in a sympathetic ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366332"}
{"pmid": "4366334", "title": "Medical management of the patient with arthritis.", "content": "Medical management of the patient with arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366334"}
{"pmid": "4366335", "title": "Tibial osteotomy for the treatment of degenerative arthritis of the knee.", "content": "Tibial osteotomy for the treatment of degenerative arthritis of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366335"}
{"pmid": "4366333", "title": "The substantia gelatinosa Rolandi of the rat. Fine structure, cytochemistry (acid phosphatase) and changes after dorsal root section.", "content": "The substantia gelatinosa Rolandi of the rat. Fine structure, cytochemistry (acid phosphatase) and changes after dorsal root section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366333"}
{"pmid": "4366338", "title": "Toxicity of collagenase: the relation to enzyme therapy of disk herniation.", "content": "Toxicity of collagenase: the relation to enzyme therapy of disk herniation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366338"}
{"pmid": "4366336", "title": "Effect of a surgical horizontal unidirectional filtered air flow unit on wound bacterial contamination and wound healing.", "content": "Effect of a surgical horizontal unidirectional filtered air flow unit on wound bacterial contamination and wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366336"}
{"pmid": "4366337", "title": "Stabilization of pathologic fractures with acrylic cement.", "content": "Stabilization of pathologic fractures with acrylic cement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366337"}
{"pmid": "4366344", "title": "Application of the cytochemical bioassay for corticotrophin to clinical and physiological studies in man.", "content": "Application of the cytochemical bioassay for corticotrophin to clinical and physiological studies in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366344"}
{"pmid": "4366345", "title": "Studies on the mechanism of cytochemical bioassays.", "content": "Studies on the mechanism of cytochemical bioassays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366345"}
{"pmid": "4366350", "title": "Cytomegalic inclusion syndrome with thrombocytopenia.", "content": "Cytomegalic inclusion syndrome with thrombocytopenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366350"}
{"pmid": "4366347", "title": "Lanthanum inhibition of the action of oxytocin on the water permeability of the frog urinary bladder: effect on the serosal and the apical membrane.", "content": "Lanthanum inhibition of the action of oxytocin on the water permeability of the frog urinary bladder: effect on the serosal and the apical membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366347"}
{"pmid": "4366351", "title": "On the Nordic Pharmacopoeia limit test for heavy metals. Heating with anhydrous sodium sulphate as a source of error.", "content": "On the Nordic Pharmacopoeia limit test for heavy metals. Heating with anhydrous sodium sulphate as a source of error.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366351"}
{"pmid": "4366352", "title": "Principles of synaptic ultrastructure in the central nervous system.", "content": "Principles of synaptic ultrastructure in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366352"}
{"pmid": "4366355", "title": "The effect of chlorhexidine on some biochemical parameters of rat liver microsomes.", "content": "The effect of chlorhexidine on some biochemical parameters of rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366355"}
{"pmid": "4366356", "title": "Serial plasma growth hormone concentration during selective removal of pituitary tumors in acromegaly.", "content": "Serial plasma growth hormone concentration during selective removal of pituitary tumors in acromegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366356"}
{"pmid": "4366357", "title": "Lymphocyte inhibition by mammary tumor virus in patients with breast cancer.", "content": "Lymphocyte inhibition by mammary tumor virus in patients with breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366357"}
{"pmid": "4366358", "title": "Collagenase activity in the alkali-burned cornea.", "content": "Collagenase activity in the alkali-burned cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366358"}
{"pmid": "4366359", "title": "Experimental liquefaction of the vitreous body.", "content": "Experimental liquefaction of the vitreous body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366359"}
{"pmid": "4366362", "title": "Functional morphology of cestode larvae.", "content": "Functional morphology of cestode larvae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366362"}
{"pmid": "4366363", "title": "Close genetic linkage of the determinants of the ribitol and D-arabitol catabolic pathways in Klebsiella aerogenes.", "content": "Close genetic linkage of the determinants of the ribitol and D-arabitol catabolic pathways in Klebsiella aerogenes. Klebsiella aerogenes strain W70 has separate inducible pathways for the degradation of the pentitols ribitol and d-arabitol. These pathways are closely linked genetically as determined by transduction with phage PW52. There are two regulatory sites for the ribitol catabolic pathway as defined by loci for mutations to constitutive synthesis of ribitol dehydrogenase and d-ribulokinase, rbtB and rbtC. The two control sites are separated by a site represented by the dalB22 mutation. This mutation deprives the cell of the ability to induce synthesis of d-arabitol dehydrogenase and d-xylulokinase activities. Two additional regulatory mutations for the d-arabitol pathway, dalC31 and dalC37, map to the opposite side of rbtB13 relative to dalB22. The order of the genetic sites thus far determined for this region is dalK-dalD-dalC31, dalC37-rbtB13-dalB22-rbtC14-rbtD-rbtK, where dalK and dalD represent structural genes for the kinase and dehydrogenase of the d-arabitol pathway, respectively, and rbtK and rbtD represent the corresponding genes for the ribitol pathway. The two mutations that lead to constitutive synthesis of the d-arabitol-induced enzymes, dalC31 and dalC37, have different phenotypes with regard to their response to xylitol. The growth of dalC31 is inhibited by xylitol, but the toxicity can be reduced by increasing the levels of ribitol dehydrogenase either by induction with ribitol or by selection of a ribitol dehydrogenase-constitutive mutation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366363"}
{"pmid": "4366364", "title": "Bladder function during lumbar myelography. An experimental investigation in cats.", "content": "Bladder function during lumbar myelography. An experimental investigation in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366364"}
{"pmid": "4366370", "title": "Low temperature photodissociation of hemoproteins: oxygenated cobalt-myoglobin and hemoglobin.", "content": "Low temperature photodissociation of hemoproteins: oxygenated cobalt-myoglobin and hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366370"}
{"pmid": "4366367", "title": "Cyclic nucleotide phosphodiesterase activities from isolated fat cells: correlation of subcellular distribution with effects of nucleotides and insulin.", "content": "Cyclic nucleotide phosphodiesterase activities from isolated fat cells: correlation of subcellular distribution with effects of nucleotides and insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366367"}
{"pmid": "4366368", "title": "Direct evidence for the involvement of epoxide intermediates in the biosynthesis of the C18 family of cutin acids.", "content": "Direct evidence for the involvement of epoxide intermediates in the biosynthesis of the C18 family of cutin acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366368"}
{"pmid": "4366369", "title": "Divalent metal ion effects on a mutant histidinol phosphate phosphatase from Salmonella typhimurium.", "content": "Divalent metal ion effects on a mutant histidinol phosphate phosphatase from Salmonella typhimurium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366369"}
{"pmid": "4366371", "title": "Characterization of porcine malate dehydrogenase. II. Amino acid sequence of a peptide containing the active center histidine residue.", "content": "Characterization of porcine malate dehydrogenase. II. Amino acid sequence of a peptide containing the active center histidine residue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366371"}
{"pmid": "4366372", "title": "Chimpanzee (Pan troglodytes) serum high density lipoproteins. Isolation and properties of their two major apolipoproteins.", "content": "Chimpanzee (Pan troglodytes) serum high density lipoproteins. Isolation and properties of their two major apolipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366372"}
{"pmid": "4366374", "title": "Biochemical and biophysical studies on cytochrome c oxidase. XVII. An epr study of the photodissociation of cytochrome a32+-CO.", "content": "Biochemical and biophysical studies on cytochrome c oxidase. XVII. An epr study of the photodissociation of cytochrome a32+-CO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366374"}
{"pmid": "4366375", "title": "Effects of ATP, antimycin and cyanide on the EPR spectra of cytochromes in phosphorylating submitochondrial particles.", "content": "Effects of ATP, antimycin and cyanide on the EPR spectra of cytochromes in phosphorylating submitochondrial particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366375"}
{"pmid": "4366376", "title": "A re-examination of succinic dehydrogenase activity and its association with cell death in the interdigit of the chick foot.", "content": "A re-examination of succinic dehydrogenase activity and its association with cell death in the interdigit of the chick foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366376"}
{"pmid": "4366377", "title": "Application of physical methods to the study of serum lipoproteins.", "content": "Application of physical methods to the study of serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366377"}
{"pmid": "4366378", "title": "Half-site reactivity.", "content": "Half-site reactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366378"}
{"pmid": "4366379", "title": "The role of the membrane in the utilization of nucleic acid precursors.", "content": "The role of the membrane in the utilization of nucleic acid precursors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366379"}
{"pmid": "4366381", "title": "Use of Xavin in auditory nerve lesions.", "content": "Use of Xavin in auditory nerve lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366381"}
{"pmid": "4366383", "title": "The inhibition of alkaline phosphatase by periodate and permanganate.", "content": "The inhibition of alkaline phosphatase by periodate and permanganate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366383"}
{"pmid": "4366382", "title": "Angiotensin I-converting enzyme of the kidney cortex.", "content": "Angiotensin I-converting enzyme of the kidney cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366382"}
{"pmid": "4366366", "title": "Complications in therapeutic soft lens wear.", "content": "Complications in therapeutic soft lens wear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366366"}
{"pmid": "4366384", "title": "Intracellular localisation and properties of aldehyde dehydrogenases from sheep liver.", "content": "Intracellular localisation and properties of aldehyde dehydrogenases from sheep liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366384"}
{"pmid": "4366385", "title": "Maleimideinactivation of lactate dehydrogenase isozymes.", "content": "Maleimideinactivation of lactate dehydrogenase isozymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366385"}
{"pmid": "4366386", "title": "Inhibitor of nitrate reductase in the roots of rice seedlings and its effect on the enzyme activity in the presence of NADH.", "content": "Inhibitor of nitrate reductase in the roots of rice seedlings and its effect on the enzyme activity in the presence of NADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366386"}
{"pmid": "4366387", "title": "Kinetics of amidophosphoribosyltransferase in intact tumor cells.", "content": "Kinetics of amidophosphoribosyltransferase in intact tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366387"}
{"pmid": "4366388", "title": "Partial purification and characterization of an adenosine 3',5'-monophosphate-dependent protein kinase from rabbit gastric mucosa.", "content": "Partial purification and characterization of an adenosine 3',5'-monophosphate-dependent protein kinase from rabbit gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366388"}
{"pmid": "4366389", "title": "Activation and phosphorylation of carbonic anhydrase by adenosine 3',5'-monophosphate-dependent protein kinases.", "content": "Activation and phosphorylation of carbonic anhydrase by adenosine 3',5'-monophosphate-dependent protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366389"}
{"pmid": "4366392", "title": "Stimulation by thyrotropin of horse thyroid plasma membranes adenylate cyclase: evidence of cooperativity.", "content": "Stimulation by thyrotropin of horse thyroid plasma membranes adenylate cyclase: evidence of cooperativity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366392"}
{"pmid": "4366390", "title": "Isolation of cyclic inositol-1,2-phosphate from mammalian cells and a probable function of phosphatidylinositol turnover.", "content": "Isolation of cyclic inositol-1,2-phosphate from mammalian cells and a probable function of phosphatidylinositol turnover.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366390"}
{"pmid": "4366391", "title": "Isoenzymes of sphingomyelinase and the genetic defect in Niemann-Pick disease, type C.", "content": "Isoenzymes of sphingomyelinase and the genetic defect in Niemann-Pick disease, type C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366391"}
{"pmid": "4366393", "title": "Lecithin biosynthesis in liver mitochondrial fractions.", "content": "Lecithin biosynthesis in liver mitochondrial fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366393"}
{"pmid": "4366394", "title": "In vitro triiodothyronine binding to non-histone proteins from rat liver nuclei.", "content": "In vitro triiodothyronine binding to non-histone proteins from rat liver nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366394"}
{"pmid": "4366396", "title": "Pulmonary carcinoma (Jaagsiekte) of sheep: pathologic findings and comparison in multiple-case and case-free herds.", "content": "Pulmonary carcinoma (Jaagsiekte) of sheep: pathologic findings and comparison in multiple-case and case-free herds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366396"}
{"pmid": "4366397", "title": "Comparative studies on some herpes simplex virus strains with different locations. 3. Cultivability in cell cultures.", "content": "Comparative studies on some herpes simplex virus strains with different locations. 3. Cultivability in cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366397"}
{"pmid": "4366399", "title": "Gene manipulation: progress and prospects.", "content": "Gene manipulation: progress and prospects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366399"}
{"pmid": "4366401", "title": "Histologic differences in breast carcinoma of Japanese and American women.", "content": "Histologic differences in breast carcinoma of Japanese and American women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366401"}
{"pmid": "4366402", "title": "Lung cancer at autopsy in a-bomb survivors and controls, Hiroshima and Nagasaki, 1961-1970. I. Autopsy findings and relation to radiation.", "content": "Lung cancer at autopsy in a-bomb survivors and controls, Hiroshima and Nagasaki, 1961-1970. I. Autopsy findings and relation to radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366402"}
{"pmid": "4366403", "title": "Hereditary tumors of the carotid bodies and chronic obstructive pulmonary disease.", "content": "Hereditary tumors of the carotid bodies and chronic obstructive pulmonary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366403"}
{"pmid": "4366405", "title": "Estimation of the mean and variance of cycle times in cinemicrographically recorded cell populations during balanced exponential growth.", "content": "Estimation of the mean and variance of cycle times in cinemicrographically recorded cell populations during balanced exponential growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366405"}
{"pmid": "4366404", "title": "Biosynthesis of yeast mitochondria. Some effects of ethidium bromide on Kluyveromyces (Saccharomyces) fragilis.", "content": "Biosynthesis of yeast mitochondria. Some effects of ethidium bromide on Kluyveromyces (Saccharomyces) fragilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366404"}
{"pmid": "4366406", "title": "Effects of indomethacin on Moloney sarcoma virus-induced tumors.", "content": "Effects of indomethacin on Moloney sarcoma virus-induced tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366406"}
{"pmid": "4366408", "title": "The study and effect of streptoxotocin (NSC-37917) rendered diabetic Chinese.", "content": "The study and effect of streptoxotocin (NSC-37917) rendered diabetic Chinese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366408"}
{"pmid": "4366409", "title": "Ultrastructure of the tegument of Schistosoma.", "content": "Ultrastructure of the tegument of Schistosoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366409"}
{"pmid": "4366410", "title": "Virologic and serologic studies on infectious mononucleosis-like disease in children, with special reference to cytomegalovirus, Epstein-Barr virus and adenovirus infections.", "content": "Virologic and serologic studies on infectious mononucleosis-like disease in children, with special reference to cytomegalovirus, Epstein-Barr virus and adenovirus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366410"}
{"pmid": "4366411", "title": "Effect of alpha-methyldopa and of spironolactone on angiotensin responsiveness in man.", "content": "Effect of alpha-methyldopa and of spironolactone on angiotensin responsiveness in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366411"}
{"pmid": "4366412", "title": "Current evaluation research on mental health services.", "content": "Current evaluation research on mental health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366412"}
{"pmid": "4366413", "title": "Ego defense patterns in manic-depressive illness.", "content": "Ego defense patterns in manic-depressive illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366413"}
{"pmid": "4366414", "title": "Intrinsic urethral peristalsis.", "content": "Intrinsic urethral peristalsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366414"}
{"pmid": "4366417", "title": "The Nader report: one author's perspective.", "content": "The Nader report: one author's perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366417"}
{"pmid": "4366415", "title": "Genetic influence on development of reticulum cell sarcomas in SJL-J mice.", "content": "Genetic influence on development of reticulum cell sarcomas in SJL-J mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366415"}
{"pmid": "4366416", "title": "Ultrastructure and function of the mesenchyme of the rat adrenal cortex.", "content": "Ultrastructure and function of the mesenchyme of the rat adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366416"}
{"pmid": "4366418", "title": "Recurrent sciatica associated with herpes simplex. Case report.", "content": "Recurrent sciatica associated with herpes simplex. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366418"}
{"pmid": "4366420", "title": "Symmetrical transcription in animal cells and viruses.", "content": "Symmetrical transcription in animal cells and viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366420"}
{"pmid": "4366419", "title": "Early changes of protein-kinase (glycogen-synthetase kinase) in denervated muscle.", "content": "Early changes of protein-kinase (glycogen-synthetase kinase) in denervated muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366419"}
{"pmid": "4366421", "title": "Erythema multiforme exudativum (Stevens-Johnson syndrome) following sodium diphenylhydantoin therapy.", "content": "Erythema multiforme exudativum (Stevens-Johnson syndrome) following sodium diphenylhydantoin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366421"}
{"pmid": "4366423", "title": "Complementation in theta-toxin production between mutants of two groups of Clostridium perfringens.", "content": "Complementation in theta-toxin production between mutants of two groups of Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366423"}
{"pmid": "4366422", "title": "Effects of short-term ozone exposure on lung mitochondrial oxidative and energy metabolism.", "content": "Effects of short-term ozone exposure on lung mitochondrial oxidative and energy metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366422"}
{"pmid": "4366425", "title": "Transmitter sensitivities of some nerve and muscle cells in culture.", "content": "Transmitter sensitivities of some nerve and muscle cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366425"}
{"pmid": "4366424", "title": "Viral infection and lipemia: a problem of disordered host physiology.", "content": "Viral infection and lipemia: a problem of disordered host physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366424"}
{"pmid": "4366426", "title": "Short-term toxicity of pentachlorophenol in rats.", "content": "Short-term toxicity of pentachlorophenol in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366426"}
{"pmid": "4366429", "title": "Isolation and characterization of temperature-sensitive mutants of vesicular stomatitis virus, New Jersey serotype.", "content": "Isolation and characterization of temperature-sensitive mutants of vesicular stomatitis virus, New Jersey serotype. Forty-eight temperature-sensitive (ts) mutants have been isolated from a wild-type strain of the New Jersey serotype of vesicular stomatitis virus (VSV) after exposure to the base analogue mutagen 5-fluorouracil. Of these mutants, 47 have been classified into 6 nonoverlapping complementation groups containing 21, 17, 4, 3, 2, and 1 mutant, respectively (1 mutant remaining unallocated). The ribonucleic acid (RNA) phenotype of 23 of these mutants has been established. Four of the six groups contain one or more mutants unable to synthesize detectable amounts of viral RNA under restrictive conditions (39 C). No complementation was observed in mixed infection with ts mutants from the five established complementation groups of the Indiana serotype of VSV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366429"}
{"pmid": "4366430", "title": "Nucleotide composition of the ribonucleic acid of rabies virus.", "content": "Nucleotide composition of the ribonucleic acid of rabies virus. The nucleotide composition of the ribonucleic acid of three strains of rabies virus was determined and found to be similar to that of vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366430"}
{"pmid": "4366428", "title": "Reinitiation within one cell cycle of the deoxyribonucleic acid synthesis induced by simian virus 40.", "content": "Reinitiation within one cell cycle of the deoxyribonucleic acid synthesis induced by simian virus 40. The infection of secondary cultures of Chinese hamster cells with simian virus 40 (SV40) induces the appearance of cells with polyploid deoxyribonucleic acid (DNA) content or chromosomal component within one cell generation. The mechanism of this phenomenon was studied by the use of 5-bromodeoxyuridine (BUdR) incorporation as a DNA density marker. When cultures were treated with (14)C-BUdR and colcemide and harvested at 48 hr postinfection, only hybrid and light DNA molecules were found in control cultures, whereas in infected cultures there were also heavy molecules. The proportion of heavy DNA synthesized during the experimental period varied from 13 to 25%. It was determined by DNA-DNA hybridization that the heavy DNA consisted of cellular DNA. In radioautographic experiments, it was shown that, under the conditions used, a fraction of the infected cell population twice replicated its complete DNA content. Analysis of the kinetics indicated that the heavy DNA resulted from the reinitiation of DNA synthesis after the initial replication of the entire cell DNA. It was concluded that, after infection with SV40, a fraction of the Chinese hamster cell population undergoes two cycles of DNA synthesis without intervening mitosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366428"}
{"pmid": "4366432", "title": "Different properties of synapses between a single sensory neurone and two different motor cells in the leech C.N.S.", "content": "Different properties of synapses between a single sensory neurone and two different motor cells in the leech C.N.S. In leech ganglia, an individual sensory cell that responds specifically to noxious mechanical stimulation of the skin (N cell) excites two different motoneurones. One raises the annuli of the skin into ridges (the AE cell), while the other innervates logitudinal muscles and thereby shortens the body segment (L cell). A comparison has been made of the way in which these two synapses behave when their common presynaptic cell is stimulated in various conditions.1. Using previously described criteria, N sensory cells have been shown to make monosynaptic chemical connexions with both the AE and L motoneurones (Nicholls & Purves, 1972). Following a single stimulus, the excitatory synaptic potential recorded in the AE motoneurone was only about one tenth the size of that in the L cell (approximately 0.5 mV compared to 5 mV). Trains of impulses in the same N sensory cell gave rise to synaptic potentials in the AE and the L motoneurones that underwent phases of facilitation and depression; the facilitation, however, was characteristically greater and longer lasting at synapses upon the AE motoneurone.2. The differences between the two synapses were accentuated in Ringer fluid containing increased concentrations of Ca and also in the cold. Under both of these conditions repetitive firing by the N sensory cell could give rise to synaptic potentials in the AE motoneurone which progressively increased in amplitude, while those in the L motoneurone became smaller.3. The results suggest that the differences in synaptic transmission can be accounted for by variations in the amount of transmitter released at the presynaptic N cell terminals, rather than by differences in the post-synaptic cells. The animal's behaviour corresponds to expectations from the physiology of the synapses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366432"}
{"pmid": "4366431", "title": "The accumulative properties of facilitation at crayfish neuromuscular synapses.", "content": "The accumulative properties of facilitation at crayfish neuromuscular synapses. 1. Synaptic facilitation was measured with intracellular recording at two classes of neuromuscular synapses in the opener muscle of the crayfish dactyl by placing a test stimulus at various intervals after either a single conditioning stimulus or a short conditioning train.2. The facilitative effect of one stimulus reaches approximately the same level with both the superficial central and superficial distal synapses. The facilitation decreases smoothly in two phases after the conditioning stimulus at superficial central synapses and in a more complex fashion at superficial distal synapses.3. The two synaptic types differ in the manner in which they add up the facilitative effects produced by each of the stimuli in a short train. With superficial distal synapses the facilitative effects of conditioning stimuli add linearly, while with superficial central synapses the facilitative effects accumulate exponentially.4. The linear addition of facilitation at superficial distal synapses is not altered when the quantal content is lowered by decreasing the external Ca concentration from 13.5 to 3 mM.5. The rate of decay of facilitation is the same following both one and three conditioning stimuli, even though the facilitation is nearly six times larger in the latter case.6. The results are discussed in terms of mechanisms for synaptic facilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366431"}
{"pmid": "4366434", "title": "Quantitative and qualitative dynamics of the epidermal and cellular inflammatory reaction in primary toxic and allergic dinitrochlorobenzene contact dermatitis in guinea pigs.", "content": "Quantitative and qualitative dynamics of the epidermal and cellular inflammatory reaction in primary toxic and allergic dinitrochlorobenzene contact dermatitis in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366434"}
{"pmid": "4366435", "title": "Quantitative determination of the conformation of cyclic 3',5'-adenosine monophosphate in solution using lanthanide ions as nuclear magnetic resonance probes.", "content": "Quantitative determination of the conformation of cyclic 3',5'-adenosine monophosphate in solution using lanthanide ions as nuclear magnetic resonance probes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366435"}
{"pmid": "4366436", "title": "Rapid viscosimetric evaluation of collagenose activity.", "content": "Rapid viscosimetric evaluation of collagenose activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366436"}
{"pmid": "4366438", "title": "Penetration and removal of horseradish peroxidase injected into the cerebrospinal fluid: role of cerebral perivascular spaces, endothelium and microglia.", "content": "Penetration and removal of horseradish peroxidase injected into the cerebrospinal fluid: role of cerebral perivascular spaces, endothelium and microglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366438"}
{"pmid": "4366437", "title": "Insulin secretion and glucose metabolism during succinylcholine paralysis in dogs.", "content": "Insulin secretion and glucose metabolism during succinylcholine paralysis in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366437"}
{"pmid": "4366448", "title": "Evolutionary divergence in the two kinds of subunits of ribulose diphosphate carboxylase isolated from different species of Nicotiana.", "content": "Evolutionary divergence in the two kinds of subunits of ribulose diphosphate carboxylase isolated from different species of Nicotiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366448"}
{"pmid": "4366449", "title": "Analysis of high molecular weight material from the polymerization of adenosine cyclic 2', 3'-phosphate.", "content": "Analysis of high molecular weight material from the polymerization of adenosine cyclic 2', 3'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366449"}
{"pmid": "4366450", "title": "Simultaneous isolation of adenosine 3',5'-cyclic monophosphate (cAMP) and guanosine 3',5'-cyclic monophosphate (cGMP) in small tissue samples.", "content": "Simultaneous isolation of adenosine 3',5'-cyclic monophosphate (cAMP) and guanosine 3',5'-cyclic monophosphate (cGMP) in small tissue samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366450"}
{"pmid": "4366451", "title": "Flotation equilibrium of serum low density lipoproteins.", "content": "Flotation equilibrium of serum low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366451"}
{"pmid": "4366452", "title": "An enzymatic, spectrophotometric glycerol assay with increased basic sensitivity.", "content": "An enzymatic, spectrophotometric glycerol assay with increased basic sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366452"}
{"pmid": "4366453", "title": "Adrenal-gonadal interactions at puberty.", "content": "Adrenal-gonadal interactions at puberty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366453"}
{"pmid": "4366454", "title": "Nuclear receptor-estrogen complex: in vivo and in vitro binding of estradiol and estriol as influenced by serum albumin.", "content": "Nuclear receptor-estrogen complex: in vivo and in vitro binding of estradiol and estriol as influenced by serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366454"}
{"pmid": "4366456", "title": "Radioimmunoassay for aldosterone and normal values under various physiological conditions.", "content": "Radioimmunoassay for aldosterone and normal values under various physiological conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366456"}
{"pmid": "4366455", "title": "Steroid excretion in the neo-natal period: a comparative study of the excretion of steroids by human, ape and rhesus monkey infants.", "content": "Steroid excretion in the neo-natal period: a comparative study of the excretion of steroids by human, ape and rhesus monkey infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366455"}
{"pmid": "4366457", "title": "Demonstration of an androgen binding protein (ABP) in rabbit testis: secretion in efferent duct fluid and passage into epididymis.", "content": "Demonstration of an androgen binding protein (ABP) in rabbit testis: secretion in efferent duct fluid and passage into epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366457"}
{"pmid": "4366459", "title": "Influence of adrenal steroidogenesis in urinary excretion of catecholamine acid metabolites.", "content": "Influence of adrenal steroidogenesis in urinary excretion of catecholamine acid metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366459"}
{"pmid": "4366458", "title": "Specificity of cyclic AMP potentiation of glucose-stimulated insulin release.", "content": "Specificity of cyclic AMP potentiation of glucose-stimulated insulin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366458"}
{"pmid": "4366460", "title": "Glucose transport in isolated brush-border and lateral-basal plasma-membrane vesicles from intestinal epithelial cells.", "content": "Glucose transport in isolated brush-border and lateral-basal plasma-membrane vesicles from intestinal epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366460"}
{"pmid": "4366462", "title": "The effect of oxygen on the photoconductivity of lipid bilayers containing magnesium-porphyrin.", "content": "The effect of oxygen on the photoconductivity of lipid bilayers containing magnesium-porphyrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366462"}
{"pmid": "4366461", "title": "On the sidedness of plasma membrane enzymes.", "content": "On the sidedness of plasma membrane enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366461"}
{"pmid": "4366463", "title": "Two variants of feedback artificially created in central motor disturbances on the base of EMG.", "content": "Two variants of feedback artificially created in central motor disturbances on the base of EMG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366463"}
{"pmid": "4366465", "title": "Photooxidative and spectral studies on cytochrome c. Conformational changes induced by binding of cardiolipin.", "content": "Photooxidative and spectral studies on cytochrome c. Conformational changes induced by binding of cardiolipin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366465"}
{"pmid": "4366467", "title": "Characteristics of the sensory discharge of the muscle spindle in Xenopus laevis.", "content": "Characteristics of the sensory discharge of the muscle spindle in Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366467"}
{"pmid": "4366468", "title": "Modification of fructose-1,6-diphosphatase with pyridoxal 5'-phosphate. Evidence for the participation of lysyl residues at the active site.", "content": "Modification of fructose-1,6-diphosphatase with pyridoxal 5'-phosphate. Evidence for the participation of lysyl residues at the active site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366468"}
{"pmid": "4366470", "title": "Chemical polymerization of oligonucleotides directed by a complementary polynucleotide. Preparation and polymerization of oligo(2'-O-methylinosine 3'-phosphate).", "content": "Chemical polymerization of oligonucleotides directed by a complementary polynucleotide. Preparation and polymerization of oligo(2'-O-methylinosine 3'-phosphate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366470"}
{"pmid": "4366471", "title": "Substrate and product inhibition in the xanthine oxidase catalyzed oxidation of acetaldehyde.", "content": "Substrate and product inhibition in the xanthine oxidase catalyzed oxidation of acetaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366471"}
{"pmid": "4366469", "title": "Neurospora arginyl transfer ribonucleic acid ligase. Binding and dissociation of transfer ribonucleic acid.", "content": "Neurospora arginyl transfer ribonucleic acid ligase. Binding and dissociation of transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366469"}
{"pmid": "4366472", "title": "Contribution of carotenoids to the optical activity of human serum low-density lipoprotein.", "content": "Contribution of carotenoids to the optical activity of human serum low-density lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366472"}
{"pmid": "4366473", "title": "Linear electric field effect measurements of variant low-spin forms of ferric cytochrome c.", "content": "Linear electric field effect measurements of variant low-spin forms of ferric cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366473"}
{"pmid": "4366474", "title": "Interactions of periodate-oxidized guanine nucleotides with Escherichia coli elongation factor G and the ribosome.", "content": "Interactions of periodate-oxidized guanine nucleotides with Escherichia coli elongation factor G and the ribosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366474"}
{"pmid": "4366475", "title": "Chemical linkage of nucleic acids to neutral and phosphorylated cellulose powders and isolation of specific sequences by affinity chromatography.", "content": "Chemical linkage of nucleic acids to neutral and phosphorylated cellulose powders and isolation of specific sequences by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366475"}
{"pmid": "4366476", "title": "The genetics of Caenorhabditis elegans.", "content": "The genetics of Caenorhabditis elegans. Methods are described for the isolation, complementation and mapping of mutants of Caenorhabditis elegans, a small free-living nematode worm. About 300 EMS-induced mutants affecting behavior and morphology have been characterized and about one hundred genes have been defined. Mutations in 77 of these alter the movement of the animal. Estimates of the induced mutation frequency of both the visible mutants and X chromosome lethals suggests that, just as in Drosophila, the genetic units in C. elegans are large.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366476"}
{"pmid": "4366477", "title": "Gel electrophoresis, isoelectric focusing, and localization of thymidine kinase in normal and simian virus 40-infected monkey cells.", "content": "Gel electrophoresis, isoelectric focusing, and localization of thymidine kinase in normal and simian virus 40-infected monkey cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366477"}
{"pmid": "4366480", "title": "Induction of common transplantation antigen by various isolates of papovavirus SV40 and by virus rescued from transformed cells.", "content": "Induction of common transplantation antigen by various isolates of papovavirus SV40 and by virus rescued from transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366480"}
{"pmid": "4366479", "title": "Enzyme activities associated with cytoplasmic polyhedrosis virus from Bombyx mori. II. Comparative studies.", "content": "Enzyme activities associated with cytoplasmic polyhedrosis virus from Bombyx mori. II. Comparative studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366479"}
{"pmid": "4366478", "title": "On the nature of the hemolytic activity of Sendai virus. A kinetic study.", "content": "On the nature of the hemolytic activity of Sendai virus. A kinetic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366478"}
{"pmid": "4366481", "title": "Sanfilippo A disease in the fetus.", "content": "Sanfilippo A disease in the fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366481"}
{"pmid": "4366482", "title": "Polysyndactyly and Marfan's syndrome.", "content": "Polysyndactyly and Marfan's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366482"}
{"pmid": "4366483", "title": "E.s.r.-spectroscopy of radiation-produced radicals in 9-ethyl adenine.", "content": "E.s.r.-spectroscopy of radiation-produced radicals in 9-ethyl adenine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366483"}
{"pmid": "4366489", "title": "Genetic variation in coumarin hydroxylase activity in the mouse (Mus musculus).", "content": "Genetic variation in coumarin hydroxylase activity in the mouse (Mus musculus). Basal and phenobarbital-induced rates of hepatic metabolism of coumarin to 7-hydroxycoumarin are markedly higher in DBA/2J mice than they are in the AKR/J, C57BL/6J, and C3H/HeJ strains. Intermediate coumarin hydroxylase activity in F(1) hybrids of mating between DBA/2J and the other three strains indicates an additive mode of inheritance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366489"}
{"pmid": "4366488", "title": "Insulin binding to isolated human adipocytes.", "content": "Insulin binding to isolated human adipocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366488"}
{"pmid": "4366491", "title": "Increased sensitivity of cell-free protein synthesis to double-stranded RNA after interferon treatment.", "content": "Increased sensitivity of cell-free protein synthesis to double-stranded RNA after interferon treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366491"}
{"pmid": "4366490", "title": "Absence of REM rebound after barbiturate withdrawal.", "content": "Absence of REM rebound after barbiturate withdrawal. Administration of three different barbiturates reduced rapid eye movement (REM) sleep. Drug withdrawal led to a return to baseline REM] values without significant overshoot. Similar results are observed with administration of benzodiazepines in pharmacologically equivalent dosages; therefore, a distinction between these two drug classes on the basis of withdrawal effects on the sleep electroencephalogram appears unwarranted. Further investigation is required determine why high REM levels are sometimes associated with the withdrawal of sedative-hypnotic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366490"}
{"pmid": "4366493", "title": "Partial suppression by UV irradiation of the mechanism of resistance to cucumber mosaic virus in a resistant cucumber cultivar.", "content": "Partial suppression by UV irradiation of the mechanism of resistance to cucumber mosaic virus in a resistant cucumber cultivar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366493"}
{"pmid": "4366492", "title": "Comparative studies on tomato aspermy and cucumber mosaic viruses. II. Virus stability.", "content": "Comparative studies on tomato aspermy and cucumber mosaic viruses. II. Virus stability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366492"}
{"pmid": "4366494", "title": "Posttranscriptional block to adenovirus replication in nonpermissive monkey cells.", "content": "Posttranscriptional block to adenovirus replication in nonpermissive monkey cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366494"}
{"pmid": "4366496", "title": "Rescue of simian virus 40 (SV 40) from SV40-transformed cells by fusion with anucleate monkey cells and variation in the yield of virus rescued by fusion with replicating or nonreplicating monkey cells.", "content": "Rescue of simian virus 40 (SV 40) from SV40-transformed cells by fusion with anucleate monkey cells and variation in the yield of virus rescued by fusion with replicating or nonreplicating monkey cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366496"}
{"pmid": "4366497", "title": "Carbohydrate composition of the membrane glycoprotein of vesicular stomatitis virus.", "content": "Carbohydrate composition of the membrane glycoprotein of vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366497"}
{"pmid": "4366498", "title": "Influence of increasing 2'-O-methylation on the interferon stimulating capacity of poly(rl)-poly(rC).", "content": "Influence of increasing 2'-O-methylation on the interferon stimulating capacity of poly(rl)-poly(rC).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366498"}
{"pmid": "4366495", "title": "Production of interferon-like substance by mouse spleen cells through contact with BHK cells persistently infected with HVJ.", "content": "Production of interferon-like substance by mouse spleen cells through contact with BHK cells persistently infected with HVJ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366495"}
{"pmid": "4366499", "title": "Transcription of herpes simplex type 1 DNA in nuclei isolated from infected HEp-2 and KB cells.", "content": "Transcription of herpes simplex type 1 DNA in nuclei isolated from infected HEp-2 and KB cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366499"}
{"pmid": "4366500", "title": "Redetermination of the RNA content and the limiting RNA size of three strains of cucumber mosaic virus.", "content": "Redetermination of the RNA content and the limiting RNA size of three strains of cucumber mosaic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366500"}
{"pmid": "4366502", "title": "Synthesis of alpha-fetoprotein by membrane-bound polysomes of rat ascites hepatoma cells.", "content": "Synthesis of alpha-fetoprotein by membrane-bound polysomes of rat ascites hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366502"}
{"pmid": "4366501", "title": "Cross-reacting tumor-associated antigen (s) among chemically induced rat colon carcinomas.", "content": "Cross-reacting tumor-associated antigen (s) among chemically induced rat colon carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366501"}
{"pmid": "4366503", "title": "Deviation in esterase isozyme pattern during early stage of hepatocarcinogenesis by 3'-methyl-4-dimethylaminoazobenzene.", "content": "Deviation in esterase isozyme pattern during early stage of hepatocarcinogenesis by 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366503"}
{"pmid": "4366504", "title": "Virus release by cell colonies derived from chickens and cultures infected with avian myeloblastosis virus.", "content": "Virus release by cell colonies derived from chickens and cultures infected with avian myeloblastosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366504"}
{"pmid": "4366505", "title": "Effect of nitrofurans antagonistic to 3'-methyl-4-dimethylaminoazobenzene in hepatocarcinogenesis and RNA polymerase activity of liver cell nuclei in rats.", "content": "Effect of nitrofurans antagonistic to 3'-methyl-4-dimethylaminoazobenzene in hepatocarcinogenesis and RNA polymerase activity of liver cell nuclei in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366505"}
{"pmid": "4366506", "title": "Proceedings: Proposed mechanisms by which autochthonous neoplasms escape immune rejection.", "content": "Proceedings: Proposed mechanisms by which autochthonous neoplasms escape immune rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366506"}
{"pmid": "4366507", "title": "Proceedings: The graded enzymic immaturity of transplanted neoplasms.", "content": "Proceedings: The graded enzymic immaturity of transplanted neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366507"}
{"pmid": "4366508", "title": "Hormonal interactions among GH, ACTH, cortisol and dexamethasone upon size of kidney, liver, and adrenal.", "content": "Hormonal interactions among GH, ACTH, cortisol and dexamethasone upon size of kidney, liver, and adrenal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366508"}
{"pmid": "4366509", "title": "Identification by immunofluorescence of adenoviral antigen in exfoliated bladder epithelial cells from patients with acute hemorrhagic cystitis.", "content": "Identification by immunofluorescence of adenoviral antigen in exfoliated bladder epithelial cells from patients with acute hemorrhagic cystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366509"}
{"pmid": "4366510", "title": "Depressed growth of Morris hepatomas and altered lysosomal hydrolases during altitudinal hypoxia.", "content": "Depressed growth of Morris hepatomas and altered lysosomal hydrolases during altitudinal hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366510"}
{"pmid": "4366511", "title": "Interferon cell species specificity: role of cell membrane receptors.", "content": "Interferon cell species specificity: role of cell membrane receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366511"}
{"pmid": "4366512", "title": "Growth of Novikoff hepatoma cells in the presence of long-chain fatty acids.", "content": "Growth of Novikoff hepatoma cells in the presence of long-chain fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366512"}
{"pmid": "4366513", "title": "Epidermal cell-leukocyte interactions in spongiform pustules of Kogoj. An ultrastructural study.", "content": "Epidermal cell-leukocyte interactions in spongiform pustules of Kogoj. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366513"}
{"pmid": "4366514", "title": "Progressive multifocal leukoencephalopathy with paramyxovirus-like structures, Hirano bodies and neurogibrillary tangles.", "content": "Progressive multifocal leukoencephalopathy with paramyxovirus-like structures, Hirano bodies and neurogibrillary tangles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366514"}
{"pmid": "4366515", "title": "Morphological and biochemical observations in the Jimpy spinal cord.", "content": "Morphological and biochemical observations in the Jimpy spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366515"}
{"pmid": "4366516", "title": "Steroid therapy of multiple myeloma and macroglobulinemia.", "content": "Steroid therapy of multiple myeloma and macroglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366516"}
{"pmid": "4366519", "title": "The molecular basis of connective tissue pathology.", "content": "The molecular basis of connective tissue pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366519"}
{"pmid": "4366517", "title": "The structure of the gills of the elasmobranch, Scyliorhinus canicula (1).", "content": "The structure of the gills of the elasmobranch, Scyliorhinus canicula (1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366517"}
{"pmid": "4366522", "title": "Characteristics of aortic diastolic pressure decay with application to the continuous monitoring of changes in peripheral vascular resistance.", "content": "Characteristics of aortic diastolic pressure decay with application to the continuous monitoring of changes in peripheral vascular resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366522"}
{"pmid": "4366523", "title": "Copper content and exchange in mammalian hearts.", "content": "Copper content and exchange in mammalian hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366523"}
{"pmid": "4366524", "title": "Effect of ischemia on capillary pressure and equivalent pore radius in capillaries of the isolated dog hind limb.", "content": "Effect of ischemia on capillary pressure and equivalent pore radius in capillaries of the isolated dog hind limb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366524"}
{"pmid": "4366526", "title": "Lipoprotein uptake and metabolism by rat aortic smooth muscle cells in tissue culture.", "content": "Lipoprotein uptake and metabolism by rat aortic smooth muscle cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366526"}
{"pmid": "4366525", "title": "Studies on the cardiomegaly of the spontaneously hypertensive rat.", "content": "Studies on the cardiomegaly of the spontaneously hypertensive rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366525"}
{"pmid": "4366520", "title": "Nerve and muscle stimulation of the rat isolated phrenic nerve-diaphragm preparation.", "content": "Nerve and muscle stimulation of the rat isolated phrenic nerve-diaphragm preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366520"}
{"pmid": "4366530", "title": "A Raman and infrared spectroscopic study of the 3-carbonyl group of pyridine nucleotide coenzymes and related model compounds.", "content": "A Raman and infrared spectroscopic study of the 3-carbonyl group of pyridine nucleotide coenzymes and related model compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366530"}
{"pmid": "4366532", "title": "Chemical studies on the cyanogen bromide peptides of rat skin collagen. Amino acid sequence of alpha 1-CB3.", "content": "Chemical studies on the cyanogen bromide peptides of rat skin collagen. Amino acid sequence of alpha 1-CB3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366532"}
{"pmid": "4366531", "title": "Separation of ribonucleotides and deoxyribonucleotides on columns of borate covalently linked to cellulose. Application to the assay of ribonucleoside diphosphate reductase.", "content": "Separation of ribonucleotides and deoxyribonucleotides on columns of borate covalently linked to cellulose. Application to the assay of ribonucleoside diphosphate reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366531"}
{"pmid": "4366535", "title": "Study of free and bound lipids of Brassica campestris, var yellow sarson.", "content": "Study of free and bound lipids of Brassica campestris, var yellow sarson.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366535"}
{"pmid": "4366537", "title": "In vitro activity of delta 6 and delta 9 desaturases in hepatomas of different growth rates.", "content": "In vitro activity of delta 6 and delta 9 desaturases in hepatomas of different growth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366537"}
{"pmid": "4366536", "title": "Unusual lipids. II. Head oil of the north atlantic pilot whale, Globicephala melaena melaena.", "content": "Unusual lipids. II. Head oil of the north atlantic pilot whale, Globicephala melaena melaena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366536"}
{"pmid": "4366521", "title": "Hyperlipoproteinaemia in peripheral arterial disease in the north of England.", "content": "Hyperlipoproteinaemia in peripheral arterial disease in the north of England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366521"}
{"pmid": "4366539", "title": "Enhancement by rat liver preparations of the gene conversion frequency induced by ethyl methanesulphonate in Saccharomyces cerevisiae.", "content": "Enhancement by rat liver preparations of the gene conversion frequency induced by ethyl methanesulphonate in Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366539"}
{"pmid": "4366538", "title": "Comparative studies of the effects of carcinogenic and antitumor agents on the DNA replication of cultured mammalian cells.", "content": "Comparative studies of the effects of carcinogenic and antitumor agents on the DNA replication of cultured mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366538"}
{"pmid": "4366541", "title": "Effect of actinomycin D, cycloheximide and puromycin on hepatic adenosine 3',5'-monophosphate in rats treated with glucagon.", "content": "Effect of actinomycin D, cycloheximide and puromycin on hepatic adenosine 3',5'-monophosphate in rats treated with glucagon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366541"}
{"pmid": "4366533", "title": "Electron-microscopic investigation of pathologic inclusions in neuron mitochondria during retrograde degeneration.", "content": "Electron-microscopic investigation of pathologic inclusions in neuron mitochondria during retrograde degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366533"}
{"pmid": "4366668", "title": "Lymphocytopoiesis after irradiation.", "content": "Lymphocytopoiesis after irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366668"}
{"pmid": "4366675", "title": "The pathology of colitis and other inflammatory diseases of the colon.", "content": "The pathology of colitis and other inflammatory diseases of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366675"}
{"pmid": "4366696", "title": "Neutrons in radiotherapy--yes or no?", "content": "Neutrons in radiotherapy--yes or no?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366696"}
{"pmid": "4366697", "title": "Biological effects of fast neutrons.", "content": "Biological effects of fast neutrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366697"}
{"pmid": "4366695", "title": "Compact cyclotron neutron dosimetry.", "content": "Compact cyclotron neutron dosimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366695"}
{"pmid": "4366752", "title": "Experimental studies on the regulation of myocardial and adipose tissue lipoprotein lipase activitites in rat.", "content": "Experimental studies on the regulation of myocardial and adipose tissue lipoprotein lipase activitites in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366752"}
{"pmid": "4366753", "title": "The electron paramagnetic resonance of oxidized clostridial ferredoxins.", "content": "The electron paramagnetic resonance of oxidized clostridial ferredoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366753"}
{"pmid": "4366754", "title": "Regulation of fructose, 1,6-bisphosphatase by histidine under gluconeogenic conditions.", "content": "Regulation of fructose, 1,6-bisphosphatase by histidine under gluconeogenic conditions. Fructose 1,6-bisphosphatase (EC 3.1.3.11) requires a free divalent metal and a metal chelate for optimum activity in the neutral pH range. The latter requirement can be satisfied by histidine, which appears to function as the chelating metabolite in vivo. Under fasting conditions, the concentrations of histidine in rabbit liver vary in the range required for activation of fructose bisphosphatase, and the enzyme itself is modified so that it becomes more responsive to histidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366754"}
{"pmid": "4366756", "title": "Pattern of immunoglobulin synthesis and assembly in a human-mouse somatic cell hybrid clone.", "content": "Pattern of immunoglobulin synthesis and assembly in a human-mouse somatic cell hybrid clone. Fusion of human peripheral blood lymphocytes, not forming detectable immunoglobulins, with mouse myeloma cells (TEPC-15), secreting mouse immunoglobulin A with known antibody activity, yielded a somatic cell hybrid clone that secreted both human and mouse immunoglobulins. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that human gamma, alpha, and light chains, as well as mouse alpha and light chains, were formed by the hybrid cells. To determine whether individual antibody molecules with both human and mouse components were secreted, medium from the hybrid cells was precipitated first with antibody against mouse immunoglobulin produced in rabbit, reduced, and alkylated, and then reprecipitated with antibody against human immunoglobulin produced in rabbit. Human gamma, alpha, and light chains were detected after electrophoresis of the immunoprecipitates on sodium dodecyl sulfate-polyacrylamide gels, indicating that antibody molecules containing both human and mouse components were secreted by the hybrid cells. These data indicate that this somatic cell hybrid clone synthesized human gamma and alpha heavy chains and human light chains, as well as mouse alpha heavy chains and mouse light chains. Some of these immunoglobulin components were assembled as hybrid antibody molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366756"}
{"pmid": "4366755", "title": "A phosphate-acceptor protein related to parvalbumins in dogfish skeletal muscle.", "content": "A phosphate-acceptor protein related to parvalbumins in dogfish skeletal muscle. A phosphate-acceptor protein was isolated from the skeletal muscle of the Pacific dogfish (Squalus acanthias) displaying properties extremely similar to those of the parvalbumins, i.e., the low-molecular-weight, soluble, Ca-binding muscle proteins found in fish and amphibians. It has the same characteristic UV spectrum, strong affinity for calcium, and immunological crossreactivity with antibodies against homogeneous dogfish parvalbumin. Although it was isolated in three states of aggregation with molecular weights of about 350,000, 75,000, and 25,000, all species dissociate in Na dodecyl sulfate into subunits of 11,000 and 13,000 molecular weight. Furthermore, whereas no phosphorylation of parvalbumins could be demonstrated under any experimental conditions, the aggregated forms could be readily phosphorylated by a cyclic AMP-independent dogfish protein kinase, but not by phosphorylase kinase. One acid-stable and base-labile phosphate group was introduced per subunit which could be rapidly released by a dogfish protein phosphatase, but only very slowly if at all by phosphorylase phosphatase. It is speculated that this \"phosphate-acceptor protein\" might represent a physiologically active form of the parvalbumins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366755"}
{"pmid": "4366757", "title": "Dominance of the senescent phenotype in heterokaryons between replicative and post-replicative human fibroblast-like cells.", "content": "Dominance of the senescent phenotype in heterokaryons between replicative and post-replicative human fibroblast-like cells. In heterokaryons between senescent and young diploid fibroblast-like cells, dominance of the former with respect to nuclear DNA synthesis (incorporation of [(3)H]thymidine) was demonstrated. For identification of the respective partners, double-layer autoradiography was used after the old cells were labeled with [(3)H]methionine and the young cells were labeled with [(14)C]thymidine. Synchrony of nuclear labeling (i.e., all nuclei in a cell labeled with [(3)H]thymidine) was observed in the majority of di- and polykaryons during the second and third of three 24-hr periods of labeling with [(3)H]thymidine. The results are compatible with either terminal differentiation or error theories of clonal senescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366757"}
{"pmid": "4366758", "title": "Localization of replicating DNA of simian virus 40 in monkey kidney cells.", "content": "Localization of replicating DNA of simian virus 40 in monkey kidney cells. Approximately 80-85% of the DNA synthesized by cells infected with simian virus 40 during a short pulse with [(3)H]thymidine is associated with host nuclear membrane components, as defined by the M-band technique. A substantial portion of this membrane-associated DNA has been shown to be viral specific by sedimentation studies and by DNA.DNA hybridization. Examination of DNA associated and unassociated with nuclear M-band by neutral sucrose gradient analysis suggested that while replicating DNA of simian virus 40 is attached to the nuclear membrane, mature component I DNA of simian virus 40 is released from the membrane upon completion of replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366758"}
{"pmid": "4366760", "title": "Effects of dialyzable transfer factor in patients with breast cancer.", "content": "Effects of dialyzable transfer factor in patients with breast cancer. Five patients with advanced breast cancer were treated with pooled dialyzable transfer factor from healthy adult donors. The period of treatment ranged from 21 to 310 days, the total dose from 20 to 257 ml. Transfer factor did not elicit inflammatory or hypersensitivity reactions or detectable formation of antibody to itself, nor any hematological or biochemical abnormalities or other side effects. Three patients became responsive (by skin test) to tuberculin and/or streptococcal antigens. Marked partial regression of the breast cancer, lasting 6 months, was observed in one patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366760"}
{"pmid": "4366759", "title": "Lipid binding to the amphipathic membrane protein cytochrome b5.", "content": "Lipid binding to the amphipathic membrane protein cytochrome b5. The lipid binding properties of the membrane protein cytochrome b(5) (detergent-extracted from calf liver microsomal preparations) were characterized by studying the interaction of spin-labeled lipids (5-, 12-, and 16-doxylstearic acid and 5- and 16-doxylphosphatidyl-choline, where doxyl refers to the nitroxide moiety) with cytochrome b(5), using electron spin resonance spectroscopy. The intact cytochrome b(5) molecule immobilizes all of the lipid spin labels, while the segment of cytochrome b(5) released by trypsin does not affect lipid mobility. The immobilization of lipid spin labels on the hydrophobic surface of intact cytochrome b(5) is not appreciably altered by associating the protein with liposomes. Differences in polarity of the lipid binding sites between cytochrome b(5) and phospholipid vesicles were also observed. The lipid binding sites on cytochrome b(5) are hydrophobic by conventional criteria, but are more polar than the interior of fluid phospholipid bilayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366759"}
{"pmid": "4366761", "title": "Glucose inhibition of adenylate cyclase in intact cells of Escherichia coli B.", "content": "Glucose inhibition of adenylate cyclase in intact cells of Escherichia coli B. Previous studies in E. coli B have demonstrated an inverse correlation between the presence of glucose in the medium and the accumulation of cyclic AMP in the medium. This observation could not be explained by the action of glucose as a repressor of adenylate cyclase (EC 4.6.1.1) synthesis, as a stabilizer of cyclic AMP phosphodiesterase (EC 3.1.4.17) activity, or as a direct inhibitor of adenylate cyclase activity in cell-free preparations. The recent development of an in vivo assay for adenylate cyclase has provided a basis for further exploring the inhibitory action of glucose in intact cells. With this assay it has been possible to show that, while glucose does not affect adenylate cyclase in vitro, it rapidly inhibits the enzyme activity in intact cells. Extensive metabolism of glucose is not required, since alpha-methylglucoside also inhibits adenylate cyclase in vivo. When cells are grown on glucose as carbon source, some sugars (mannose, glucosamine) substitute for glucose as adenylate cyclase inhibitors while others (e.g., fructose) do not. Dose-response studies indicate that low concentrations of glucose lead to essentially complete inhibition of adenylate cyclase activity while only moderately decreasing intracellular cyclic AMP concentrations. The evidence presented suggests that the decreased cellular cyclic AMP levels resulting from glucose addition can be accounted for by inhibition of adenylate cyclase without any significant effect on cyclic AMP phosphodiesterase or the transport of cyclic AMP from the cells to the medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366761"}
{"pmid": "4366762", "title": "Isolation of the major viral glycoprotein and a putative precursor from cells transformed by avian sarcoma viruses.", "content": "Isolation of the major viral glycoprotein and a putative precursor from cells transformed by avian sarcoma viruses. Immune precipitation with a monospecific antiserum was employed to study the synthesis of the major viral glycoprotein gp85. Labeled gp85 was detectable by polyacrylamide gel electrophoresis of immune precipitates prepared from lysates of transformed cells which had been labeled for long term with radioactive amino acid or fucose. When immune precipitates were prepared from lysates of cells pulse-labeled with radioactive amino acid, the bulk of the precipitated counts did not appear in gp85 but in a heterogeneous protein fraction with a mean molecular weight of approximately 70,000; this fraction has been designated p70. If, however, the pulse label was followed by incubation of the cells in medium containing excess unlabeled amino acid, the bulk of the precipitated counts comigrated with gp85. Similar pulse-labeling experiments with radioactive fucose and glucosamine suggested that p70 represents incompletely glycosylated precursor to gp85.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366762"}
{"pmid": "4366763", "title": "The isolation and characterization of a new iron-sulfur protein from photosynthetic membranes.", "content": "The isolation and characterization of a new iron-sulfur protein from photosynthetic membranes. A new iron-sulfur protein, distinct from the soluble chloroplast ferredoxin, was isolated from chloroplast membranes. The isolated protein, purified to homogeneity, had a molecular weight of about 8000 and 4 atoms of iron and 4 inorganic sulfides per mole. Its absorption spectrum had a broad absorbance band in the 400 nm region, a shoulder at approximately 310 nm, and a peak around 280 nm. The absorbance ratio A(400) to A(280) was 0.55. The electron paramagnetic resonance spectrum (measured at 12 degrees K) of the reduced protein was similar to that of other reduced iron-sulfur proteins, showing a major resonance line at g = 1.94. The isolated protein, when photoreduced by spinach chloroplasts, can in turn transfer electrons to mammalian cytochrome c. However, the photoreduced protein cannot replace soluble ferredoxin in NADP(+) reduction because of its apparent inability to interact with the chloroplast enzyme, ferredoxin-NADP(+) reductase. The relation of the isolated iron-sulfur protein to the bound ferredoxin that acts as the primary electron acceptor in Photosystem I is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366763"}
{"pmid": "4366764", "title": "Regulation of adenylate kinase and creatine kinase activities in myogenic cells.", "content": "Regulation of adenylate kinase and creatine kinase activities in myogenic cells. The regulation of the specific activities of adenylate kinase (EC 2.7.4.3) and creatine kinase (EC 2.7.3.2) in myogenic cell lines is independent of cell fusion. The observed increases in enzyme specific activities are cell density dependent, and may be further broken down into contributions from an increase in enzyme activity per cell and a decrease in protein per cell. Only the former appears to be affected by medium conditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366764"}
{"pmid": "4366765", "title": "The homopolyadenylate and adjacent nucleotides at the 3'-terminus of 30-40s RNA subunits in the genome of murine sarcoma-leukemia virus.", "content": "The homopolyadenylate and adjacent nucleotides at the 3'-terminus of 30-40s RNA subunits in the genome of murine sarcoma-leukemia virus. Adenosine is the major 3'OH-terminal nucleoside of the 60-70S RNA genome of the murine sarcoma-leukemia virus, its 30-40S RNA subunits, and the poly(A) segments derived by RNase treatment of both RNA species, as determined by periodate oxidation-[(3)H]-borohydride reduction. The binding 30-40S RNA to oligo(dT)-cellulose suggests that most viral RNA subunits contain poly(A). The molecular weight of poly(A) derived from viral RNA by digestion with RNase and purified by affinity chromatography is 64,000-68,000, as determined by gel electrophoresis. From the size of poly(A) and the poly(A) content of viral RNA (1.6%), it is estimated that there is about one poly(A) segment for each viral 30-40S RNA subunit. The results of 3'-termini labeling with [(3)H]borohydride, in vivo labeling with [(3)H]adenosine, and base composition of [(32)P]poly(A) indicate that a homopoly(A) segment is located at the 3'-end of a 30-40S RNA subunit. The homogeneous poly(A) segments isolated from RNase T1 digests of 60-70S [(32)P]RNA consist of one cytidylate, one uridylate, and about 190 adenylate residues, while those isolated from RNase A digests consist exclusively of adenylate residues. These results indicate that -G(C,U)A(190)A(OH) is the 3'-terminal nucleotide sequence of the viral 30-40S RNA subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366765"}
{"pmid": "4366766", "title": "Induction of a lactogenic receptor in rat liver: influence of estrogen and the pituitary.", "content": "Induction of a lactogenic receptor in rat liver: influence of estrogen and the pituitary. A receptor exists in female rat liver with high specificity for lactogenic hormones. Previous work showed the receptor level increased at the time of puberty in female but not male animals. Pregnancy caused a further substantial increase. Here we show that estrone (50 mug/day) administration to male rats induced a 10- to 30-fold increase in specific binding of ovine prolactin and human growth hormone after 8-12 days with a significant increase first seen after 4 but not 2 days of injection. In females, this regimen increased binding to pregnancy levels. In prepuberal (20-days-old) male and female rats, estrone was also markedly stimulatory. The binding sites for ovine prolactin and human growth hormone were of high affinity in liver membranes from both female and estrone-treated male rats (K(a) = 0.6 to 1.4 x 10(9) M(-1)). Estrone and estradiol were equally effective in inducing the lactogenic receptor. Estriol (50 mug/day), progesterone (500 mug/day), human placental lactogen (1 mg/day), and testosterone (100 mug/day) were without influence. Hypophysectomy drastically decreased the levels of lactogenic receptor in mature female rats, and estrogen treatment failed to restore receptor levels to normal. Hypophysectomized male rats were also unresponsive to estrogen. Throughout these studies the specific binding of (125)I-labeled insulin remained relatively constant. This work demonstrates estrogen induction of a lactogenic receptor. The pituitary gland appears to have a critical, though presently undefined, role in the induction process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366766"}
{"pmid": "4366767", "title": "Short-term binding and hydrolysis of cyclic 3':5'-adenosine monophosphate by aggregating Dictyostelium cells.", "content": "Short-term binding and hydrolysis of cyclic 3':5'-adenosine monophosphate by aggregating Dictyostelium cells. Transient binding of cyclic AMP to aggregating cells of Dictyostelium discoideum was measured under cyclic GMP excess in order to inhibit cyclic AMP hydrolysis by cell-bound phosphodiesterase. Cyclic GMP extended the period of half-maximal cyclic AMP binding from less than 5 sec to 1-2 min. With the same time course as bound cyclic AMP was released from the cells, labeled 5'-AMP appeared in the medium. Specificity, kinetics, and developmental regulation suggest that the cyclic AMP-binding sites exposed in living cells are identical with receptor sites for the chemotactic response. The functioning of the cyclic AMP-receptor/phosphodiesterase system and its formal similarity with the synaptic acetylcholine-receptor/esterase system are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366767"}
{"pmid": "4366768", "title": "Effect of poliovirus double-stranded RNA on viral and host-cell protein synthesis.", "content": "Effect of poliovirus double-stranded RNA on viral and host-cell protein synthesis. Cell-free protein-synthesizing systems that initiate on endogenous messenger RNA have been developed from uninfected and poliovirus-infected HeLa cells. Poliovirus double-stranded RNA is an effective inhibitor of protein synthesis in these extracts, and both cell-directed and virus-specific protein synthesis are equally sensitive to the inhibitory action of double-stranded RNA. The concentrations of double-stranded RNA required for inhibition are not achieved in the infected cell at early times after infection when host-cell shut-off occurs, but rather are achieved only late in infection when virus-specific protein synthesis begins to decline. This indicates that double-stranded RNA does not act as a direct agent to inhibit host cell protein synthesis following infection by poliovirus. The possible significance of inhibition by double-stranded RNA of poliovirus-specific protein synthesis is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366768"}
{"pmid": "4366769", "title": "Kinetic properties and electron paramagnetic resonance spectra of the nitric oxide derivative of hemoglobin components of trout (Salmo irideus).", "content": "Kinetic properties and electron paramagnetic resonance spectra of the nitric oxide derivative of hemoglobin components of trout (Salmo irideus). The binding of nitric oxide to hemoglobin components of trout (Salmo irideus), i.e., Hb trout I and Hb trout IV, has been studied by optical and electron paramagnetic resonance spectroscopy. Kinetic studies show that the Root effect in Hb trout IV is operative also for NO, since a large increase in the dissociation velocity constant (j(4)) is observed as the pH is decreased below 7. Moreover, the time course of the displacement of NO by CO is heterogeneous, suggesting that alpha and beta chains may have different j(4) values. Low-temperature X-band electron paramagnetic resonance spectra have been recorded with Hb trout I and IV saturated with NO at different pH values. The spectra of Hb trout IV are strongly pH-dependent. The high-pH form (pH 8.1) shows axial symmetry and no resolved hyperfine splitting, while the low-pH form is rhombic with a hyperfine splitting of 6.5 G in the g(z) region. The latter form reflects a more distorted site with a more significant delocalization of the unpaired electron on the proximal histidine; both features indicate a destabilization of the ligand binding at low pH. On the other hand, spectra of Hb trout I are axial at both pH values, with hyperfine splitting of 16.5 G, indicating that the site is not distorted and interacts with the ligand very strongly at either pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366769"}
{"pmid": "4366770", "title": "Phosphate metabolism in intact human erythrocytes: determination by phosphorus-31 nuclear magnetic resonance spectroscopy.", "content": "Phosphate metabolism in intact human erythrocytes: determination by phosphorus-31 nuclear magnetic resonance spectroscopy. Whole human blood was examined by (31)P nuclear magnetic resonance spectroscopy. Individual phosphates (alpha,beta,gamma) of ATP were identifiable, and two microenvironments appeared to be present for this molecule. When sequential recordings of freshly collected blood were made, 2,3-diphosphoglycerate was observed to decrease in association with a concomitant increase in inorganic orthophosphate. When aged cells containing little 2,3-diphosphoglycerate were incubated in the presence of inosine and pyruvate, 2,3-diphosphoglycerate formation could be demonstrated. These results show that cellular metabolism can be recorded directly in intact cells by (31)P nuclear magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366770"}
{"pmid": "4366772", "title": "Demonstration of dopamine-sensitive adenylate cyclase in malignant neuroblastoma cells and change in sensitivity of adenylate cyclase to catecholamines in \"differentiated\" cells.", "content": "Demonstration of dopamine-sensitive adenylate cyclase in malignant neuroblastoma cells and change in sensitivity of adenylate cyclase to catecholamines in \"differentiated\" cells. Adenylate cyclase (EC 4.6.1.1) activity was stimulated by low concentrations of dopamine and apomorphine, but not by low concentrations of norepinephrine in homogenates of malignant mouse neuroblastoma cells. In cyclic AMP-induced \"differentiated\" cells, dopamine concentration required for a maximal increase in adenylate cyclase activity was about 10-fold less than that required for a similar increase in control cells, and norepinephrine-sensitive adenylate cyclase activity became apparent at low norepinephrine concentrations. The pharmacological properties of dopamine-sensitive adenylate cyclase were different from those of norepinephrine-sensitive enzyme. For example, dopamine-stimulated adenylate cyclase activity was markedly reduced by low concentrations of haloperidol and phentolamine, whereas norepinephrine-stimulated enzyme activity required higher concentrations of these blocking agents for a similar amount of inhibition. Norepinephrine-stimulated enzyme activity was markedly blocked by low concentrations of propranolol, whereas dopamine-stimulated enzyme activity required a much higher concentration of this blocking agent for a similar amount of inhibition. Low concentrations of isoproterenol increased adenylate cyclase activity in malignant cells, but in \"differentiated\" cells even a high concentration failed to do so. The fact that dopamine and norepinephrine produced an additive stimulatory effect on adenylate cyclase activity suggests that they interact at different receptor sites. This suggestion is further supported by the observation that the combination of prostaglandin E(1) and norepinephrine produced an additive stimulatory effect of enzyme activity. The observation that the effects of dopamine and prostaglandin E(1) are not additive, coupled with the observation that a low concentration of phentolamine blocked the effect of prostaglandin E(1), suggests that these two agents may interact at a common site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366772"}
{"pmid": "4366773", "title": "The mechanism of viral replication. Structure of replication complexes of encephalomyocarditis virus.", "content": "The mechanism of viral replication. Structure of replication complexes of encephalomyocarditis virus. The structure of the purified replicative intermediate of encephalomyocarditis virus was determined by electron microscopy. Approximately 80% of the replicative intermediate complexes were characterized by a filament of double-stranded RNA of widely variable length, which had a \"bush\" of single-stranded RNA at one end. In many examples one or more additional single-stranded bushes were appended internally to the double-stranded RNA filament. These results support the view that before deproteinization, replicative intermediate contains little if any double-stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366773"}
{"pmid": "4366771", "title": "Cholera toxin mimics melanocyte stimulating hormone in inducing differentiation in melanoma cells.", "content": "Cholera toxin mimics melanocyte stimulating hormone in inducing differentiation in melanoma cells. Cholera toxin (choleragen) and melanocyte stimulating hormone alter within hours the morphology of melanoma cells in culture, and they slow the growth of serum-stimulated cells. After 7-10 days, cells exposed to choleragen or hormone show increased size and a fibroblastic growth pattern. Tyrosinase (EC 1.14.18.1; monophenol monooxygenase) activity increases after 3 days in the presence of 10(-8) M hormone or 10(-10) M choleragen. Binding studies with (125)I-labeled choleragen indicate that although a melanoma cell can bind a maximum of 10(6) molecules of cholera toxin, only about 4000 binding sites must be occupied to achieve maximum stimulation of tyrosinase activity. Melanocyte stimulating hormone and choleragen probably have different membrane-binding sites. After exposure to choleragen for 5 min, membrane adenylate cyclase (EC 4.6.1.1) activity increases dramatically upon further incubation of intact cells for several hours at 37 degrees and falls slowly to basal values over a period of more than 10 days. Hormone stimulation of adenylate cyclase is rapidly reversed by washing the cells, but subsequent restimulation of cyclase by the hormone is impaired. These studies indicate that cAMP mediates the effects of melanocyte stimulating hormone on growth and morphology as well as on tyrosinase activity. Cholera toxin may permanently activate the available adenylate cyclase molecules, and the protracted decay of stimulation that follows may reflect the biological turnover of adenylate cyclase molecules in these cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366771"}
{"pmid": "4366774", "title": "Acquirement of fetal properties in hepatoma on glutathione metabolism.", "content": "Acquirement of fetal properties in hepatoma on glutathione metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366774"}
{"pmid": "4366775", "title": "Hormonal regulation of hepatic and jejunal formiminotransferase activity in man and rat.", "content": "Hormonal regulation of hepatic and jejunal formiminotransferase activity in man and rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366775"}
{"pmid": "4366776", "title": "Correlations between the enzymatic activities and the factors active on blood coagulation and platelet aggregation from the venom of Vipera aspis.", "content": "Correlations between the enzymatic activities and the factors active on blood coagulation and platelet aggregation from the venom of Vipera aspis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366776"}
{"pmid": "4366777", "title": "SV40 nucleoprotein complex activity unwinds superhelical turns in SV40 DNA.", "content": "SV40 nucleoprotein complex activity unwinds superhelical turns in SV40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366777"}
{"pmid": "4366779", "title": "Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat fat cells.", "content": "Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366779"}
{"pmid": "4366778", "title": "Binding of concanavalin A and ricin to synaptic junctions of rat brain.", "content": "Binding of concanavalin A and ricin to synaptic junctions of rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366778"}
{"pmid": "4366780", "title": "Constitutivity of the HCG-receptor protein in the testis of rat and man.", "content": "Constitutivity of the HCG-receptor protein in the testis of rat and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366780"}
{"pmid": "4366781", "title": "Release of cyclic AMP from rat superior cervical ganglia after stimulation of synthesis in vitro.", "content": "Release of cyclic AMP from rat superior cervical ganglia after stimulation of synthesis in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366781"}
{"pmid": "4366782", "title": "The effect of angiotensin upon the vasculature of the isolated perfused rat kidney.", "content": "The effect of angiotensin upon the vasculature of the isolated perfused rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366782"}
{"pmid": "4366783", "title": "Meiotic drive in tn-bearing mouse spermatozoa: a relationship between aerobic respiration and transmission frequency.", "content": "Meiotic drive in tn-bearing mouse spermatozoa: a relationship between aerobic respiration and transmission frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366783"}
{"pmid": "4366786", "title": "The somatomedins: a family of insulinlike hormones under growth hormone control.", "content": "The somatomedins: a family of insulinlike hormones under growth hormone control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366786"}
{"pmid": "4366787", "title": "MSH, cyclic AMP, and melanocyte differentiation.", "content": "MSH, cyclic AMP, and melanocyte differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366787"}
{"pmid": "4366788", "title": "Interpreting the failures to confirm the depression of cerebellar Purkinje cells by cyclic AMP.", "content": "Interpreting the failures to confirm the depression of cerebellar Purkinje cells by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366788"}
{"pmid": "4366789", "title": "D(--)-lactic acid and d(--)-lactate dehydrohgenase in octopus spermatozoa.", "content": "D(--)-lactic acid and d(--)-lactate dehydrohgenase in octopus spermatozoa. The spermatozoa of Octopus dofleini martini produce anaerobically D(-)-lactic acid and possess a very active D(-)-lactate dehydrogenase. In this respect, while resembling certain microorganisms, they differ strikingly from mammalian spermatozoa which produce L(+)-lactic acid and contain L(+)-lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366789"}
{"pmid": "4366790", "title": "The spectrum of antibacterial activity of human amniotic fluid determined by scanning electron microscopy.", "content": "The spectrum of antibacterial activity of human amniotic fluid determined by scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366790"}
{"pmid": "4366791", "title": "Serum estradiol-17beta and serum human chorionic gonadotropin in patients with hydatidiform moles.", "content": "Serum estradiol-17beta and serum human chorionic gonadotropin in patients with hydatidiform moles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366791"}
{"pmid": "4366792", "title": "Progesterone concentrations in the sera of patients with intact and aborted hydatidiform moles.", "content": "Progesterone concentrations in the sera of patients with intact and aborted hydatidiform moles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366792"}
{"pmid": "4366793", "title": "Quantitation of the lecithin-sphingomyelin ratio in amniotic fluid by a simple charring method.", "content": "Quantitation of the lecithin-sphingomyelin ratio in amniotic fluid by a simple charring method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366793"}
{"pmid": "4366794", "title": "Respiratory movements in fetal rhesus monkeys.", "content": "Respiratory movements in fetal rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366794"}
{"pmid": "4366795", "title": "Studies on the luteinizing hormone- and follicle-stimulating hormone-releasing mechanism in the testicular feminization syndrome. Hypothalamic-pituitary responsiveness to clomiphene, luteinizing hormone-releasing hormone, gonadectomy, and sexual steroids.", "content": "Studies on the luteinizing hormone- and follicle-stimulating hormone-releasing mechanism in the testicular feminization syndrome. Hypothalamic-pituitary responsiveness to clomiphene, luteinizing hormone-releasing hormone, gonadectomy, and sexual steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366795"}
{"pmid": "4366796", "title": "Viral teratogenesis: a review with experimental and clinical perspectives.", "content": "Viral teratogenesis: a review with experimental and clinical perspectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366796"}
{"pmid": "4366797", "title": "Cyclic AMP, ATP and cell contact.", "content": "Cyclic AMP, ATP and cell contact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366797"}
{"pmid": "4366798", "title": "Correlations between plasma ACTH concentrations and breathing movements in foetal sheep.", "content": "Correlations between plasma ACTH concentrations and breathing movements in foetal sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366798"}
{"pmid": "4366799", "title": "Herpes simplex viruses: discrimination of types and correlation between different characteristics.", "content": "Herpes simplex viruses: discrimination of types and correlation between different characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366799"}
{"pmid": "4366800", "title": "Mink cell line Mv 1 Lu (CCL 64). Focus formation and the generation of \"nonproducer\" transformed cell lines with murine and feline sarcoma viruses.", "content": "Mink cell line Mv 1 Lu (CCL 64). Focus formation and the generation of \"nonproducer\" transformed cell lines with murine and feline sarcoma viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366800"}
{"pmid": "4366801", "title": "The nucleotide sequence of chicken 5S ribosomal RNA.", "content": "The nucleotide sequence of chicken 5S ribosomal RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366801"}
{"pmid": "4366802", "title": "Potentiated acid 1,5 pentanedial solution--a new chemical sterilizing and disinfecting agent.", "content": "Potentiated acid 1,5 pentanedial solution--a new chemical sterilizing and disinfecting agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366802"}
{"pmid": "4366803", "title": "Zonal electrophoresis and isoelectric focusing of proteins and virus particles in density gradients of small volume.", "content": "Zonal electrophoresis and isoelectric focusing of proteins and virus particles in density gradients of small volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366803"}
{"pmid": "4366804", "title": "Analysis of hydroxyproline and hydroxylysine by gas chromatography.", "content": "Analysis of hydroxyproline and hydroxylysine by gas chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366804"}
{"pmid": "4366805", "title": "The steroid specificity of the estrogen-receptor of human breast carcinoma.", "content": "The steroid specificity of the estrogen-receptor of human breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366805"}
{"pmid": "4366807", "title": "Quantitative histologic distribution of adenosine-3',5'-monophosphate in the rat stomach. Improved procedure for the luminescence assay.", "content": "Quantitative histologic distribution of adenosine-3',5'-monophosphate in the rat stomach. Improved procedure for the luminescence assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366807"}
{"pmid": "4366806", "title": "Mechanism of estrogen action--independence of several responses of the rat uterus from the early increase in adenosine 3',5'-cyclic monophosphate.", "content": "Mechanism of estrogen action--independence of several responses of the rat uterus from the early increase in adenosine 3',5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366806"}
{"pmid": "4366808", "title": "Involvement of the anticodon region of Escherichia coli tRNAGln and tRNAGlu in the specific interaction with cognate aminoacyl-tRNA synthetase. Alteration of the 2-thiouridine derivatives located in the anticodon of the tRNAs by BrCN or sulfur deprivation.", "content": "Involvement of the anticodon region of Escherichia coli tRNAGln and tRNAGlu in the specific interaction with cognate aminoacyl-tRNA synthetase. Alteration of the 2-thiouridine derivatives located in the anticodon of the tRNAs by BrCN or sulfur deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366808"}
{"pmid": "4366810", "title": "Nucleases in HeLa cell nucleoplasm and nucleoli.", "content": "Nucleases in HeLa cell nucleoplasm and nucleoli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366810"}
{"pmid": "4366809", "title": "Ribosomal RNA homologies in flowering plants: comparison of the nucleotide sequences in 5.8-S rRNA from broad bean, dwarf bean, tomato, sunflower and rye.", "content": "Ribosomal RNA homologies in flowering plants: comparison of the nucleotide sequences in 5.8-S rRNA from broad bean, dwarf bean, tomato, sunflower and rye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366809"}
{"pmid": "4366812", "title": "Lateral phase separations in Escherichia coli membranes.", "content": "Lateral phase separations in Escherichia coli membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366812"}
{"pmid": "4366813", "title": "Tumors of the submandibular gland.", "content": "Tumors of the submandibular gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366813"}
{"pmid": "4366814", "title": "Structural differences in the adenylate kinase enzymes.", "content": "Structural differences in the adenylate kinase enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366814"}
{"pmid": "4366815", "title": "Activity of microsomal enzymes in the livers of rats fed rapeseed oil.", "content": "Activity of microsomal enzymes in the livers of rats fed rapeseed oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366815"}
{"pmid": "4366816", "title": "Pathology of ulcerogenic and diarrheogenic tumors of the pancreas.", "content": "Pathology of ulcerogenic and diarrheogenic tumors of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366816"}
{"pmid": "4366818", "title": "The effect of partial degradation of mitochondrial phospholipids by phospholipase A on the temperature dependence of succinate-cytochrome c reductase and cytochrome c oxidase.", "content": "The effect of partial degradation of mitochondrial phospholipids by phospholipase A on the temperature dependence of succinate-cytochrome c reductase and cytochrome c oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366818"}
{"pmid": "4366817", "title": "Studies on the stability of rat liver D-glucose-6-phosphate phosphohydrolase (EC 3.1.3.9).", "content": "Studies on the stability of rat liver D-glucose-6-phosphate phosphohydrolase (EC 3.1.3.9).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366817"}
{"pmid": "4366819", "title": "Uptake and accumulation of purine bases by stationary yeast cells pretreated with glucose.", "content": "Uptake and accumulation of purine bases by stationary yeast cells pretreated with glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366819"}
{"pmid": "4366833", "title": "Partitioning turkey blood plasma and egg yolk lipoproteins using agarose gel.", "content": "Partitioning turkey blood plasma and egg yolk lipoproteins using agarose gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366833"}
{"pmid": "4366832", "title": "Regulation of membrane lipid fluidity in Acholeplasma laidlawii: effect of carotenoid pigment content.", "content": "Regulation of membrane lipid fluidity in Acholeplasma laidlawii: effect of carotenoid pigment content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366832"}
{"pmid": "4366834", "title": "Hematological responses associated with resistance to Rous sarcomas in four strains of chickens.", "content": "Hematological responses associated with resistance to Rous sarcomas in four strains of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366834"}
{"pmid": "4366840", "title": "Chemistry of technetium 99m.", "content": "Chemistry of technetium 99m.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366840"}
{"pmid": "4366843", "title": "Effect of caffeine on the neuromuscular junction of the frog, and its relation to external calcium concentration.", "content": "Effect of caffeine on the neuromuscular junction of the frog, and its relation to external calcium concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366843"}
{"pmid": "4366844", "title": "Analysis of the relationship between 99mTc-Sn-polyphosphate and 99mTc-Sn-pyrophosphate.", "content": "Analysis of the relationship between 99mTc-Sn-polyphosphate and 99mTc-Sn-pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366844"}
{"pmid": "4366846", "title": "A new electrophoretic technique for mouse, human, and Chinese hamster galactokinase.", "content": "A new electrophoretic technique for mouse, human, and Chinese hamster galactokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366846"}
{"pmid": "4366845", "title": "The diagnostic value of bronchial washing in lung cancer.", "content": "The diagnostic value of bronchial washing in lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366845"}
{"pmid": "4366848", "title": "Intraocular and optic nerve sheath hemorrhage in cases of sudden intracranial hypertension.", "content": "Intraocular and optic nerve sheath hemorrhage in cases of sudden intracranial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366848"}
{"pmid": "4366847", "title": "Blood loss and factors affecting pulmonary antibacterial defenses.", "content": "Blood loss and factors affecting pulmonary antibacterial defenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366847"}
{"pmid": "4366835", "title": "Estradiol mustard (NSC-112259) and phenester (NSC-116785): possible mediation of action by estrogen binding protein.", "content": "Estradiol mustard (NSC-112259) and phenester (NSC-116785): possible mediation of action by estrogen binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366835"}
{"pmid": "4366849", "title": "Ganglion of the peroneal nerve. Report of two cases.", "content": "Ganglion of the peroneal nerve. Report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366849"}
{"pmid": "4366850", "title": "The Mongolian gerbil as a model for lead toxicity. I. Studies of acute poisoning.", "content": "The Mongolian gerbil as a model for lead toxicity. I. Studies of acute poisoning. Mongolian gerbils fed diets containing lead acetate maintained body weight comparable to gerbils fed the same diet without added lead. Intranuclear lead inclusion bodies in epithelial cells of the proximal convoluted tubules of the kidney were first observed at 4 weeks, and increased in number to about 50 per high power field at 12 weeks. At this time, a corticomedullary area of empty-appearing tubules was prominent. Transmission electron microscopy confirmed the increase in number and size of nuclear lead inclusion over the 12-week period. Cytoplasmic changes observed in proximal tubule cells containing lead inclusions were considered indicative of acute lethal injury. Distinct cytoplasmic fibrillar structures, first apparent at 8 weeks, were present in some proximal tubular lining cells and strongly resembled newly formed intranuclear lead inclusions. After 12 weeks, the total amount of lead present in the gerbil kidney was four to six times greater than that in rat kidney as determined by atomic absorption spectrophotometry. A hypothesis has been formulated that relates the more efficient nephron of the gerbil kidney to the rapid and extensive development of intranuclear inclusion bodies and the greater accumulation of total lead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366850"}
{"pmid": "4366852", "title": "Some effects of 5-bromodeoxyuridine on polyoma-transformed mouse cells.", "content": "Some effects of 5-bromodeoxyuridine on polyoma-transformed mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366852"}
{"pmid": "4366851", "title": "Induction of alkaline phosphatase activity by dibutyryl adenosine 3':5'-cyclic monophosphate in aneuploid rat liver cells.", "content": "Induction of alkaline phosphatase activity by dibutyryl adenosine 3':5'-cyclic monophosphate in aneuploid rat liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366851"}
{"pmid": "4366853", "title": "Ultrastructural localization of SV40 viral DNA in cells, during lytic infection, by in situ molecular hybridization.", "content": "Ultrastructural localization of SV40 viral DNA in cells, during lytic infection, by in situ molecular hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366853"}
{"pmid": "4366854", "title": "Ribosomal protein differences between animal cells.", "content": "Ribosomal protein differences between animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366854"}
{"pmid": "4366856", "title": "A hospital's support systems for chronic patients living in the community.", "content": "A hospital's support systems for chronic patients living in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366856"}
{"pmid": "4366857", "title": "Holding tea groups: a home visiting program for chronic schizophrenics.", "content": "Holding tea groups: a home visiting program for chronic schizophrenics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366857"}
{"pmid": "4366858", "title": "Boerum Hill: a private long-term residential program for former mental patients.", "content": "Boerum Hill: a private long-term residential program for former mental patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366858"}
{"pmid": "4366855", "title": "A diseases of Sokoto goats resembling \"peste des petits ruminants\".", "content": "A diseases of Sokoto goats resembling \"peste des petits ruminants\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366855"}
{"pmid": "4366859", "title": "Inhibitory effects in the cuneate nucleus produced by vago-aortic afferent fibers.", "content": "Inhibitory effects in the cuneate nucleus produced by vago-aortic afferent fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366859"}
{"pmid": "4366860", "title": "Disynaptic corticospinal effects in forelimb motoneurones in the cat.", "content": "Disynaptic corticospinal effects in forelimb motoneurones in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366860"}
{"pmid": "4366862", "title": "Effect of prolonged alcohol administration on calcium transport in heart muscle of the dog.", "content": "Effect of prolonged alcohol administration on calcium transport in heart muscle of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366862"}
{"pmid": "4366867", "title": "Perthes-like changes in the syndrome of caudal regression.", "content": "Perthes-like changes in the syndrome of caudal regression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366867"}
{"pmid": "4366869", "title": "Ochratoxin A, an inhibitor of mitochondrial transport systems.", "content": "Ochratoxin A, an inhibitor of mitochondrial transport systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366869"}
{"pmid": "4366870", "title": "Virus encephalitis: pathogenesis in the immature brain.", "content": "Virus encephalitis: pathogenesis in the immature brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366870"}
{"pmid": "4366872", "title": "Some chemical aspects of dose-response relationships in alkylation mutagenesis.", "content": "Some chemical aspects of dose-response relationships in alkylation mutagenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366872"}
{"pmid": "4366873", "title": "Caffeine-induced enhancement of chromosome damage in human lymphocytes treated with methyl-methanesulphonate, mitomycin C and X-rays.", "content": "Caffeine-induced enhancement of chromosome damage in human lymphocytes treated with methyl-methanesulphonate, mitomycin C and X-rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366873"}
{"pmid": "4366876", "title": "Cytomegalovirus infection and sudden death in infants.", "content": "Cytomegalovirus infection and sudden death in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366876"}
{"pmid": "4366877", "title": "Early eruption of deciduous and permanent teeth: a case report.", "content": "Early eruption of deciduous and permanent teeth: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366877"}
{"pmid": "4366878", "title": "A modified gas chromatographic method for lactate analysis.", "content": "A modified gas chromatographic method for lactate analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366878"}
{"pmid": "4366879", "title": "Identification of a vasopressin-neurophysin and of an oxytocin-neurophysin in man.", "content": "Identification of a vasopressin-neurophysin and of an oxytocin-neurophysin in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366879"}
{"pmid": "4366880", "title": "Effects of neurogenic and systemic stresses on hypothalamic and adenohypophysial cAMP content.", "content": "Effects of neurogenic and systemic stresses on hypothalamic and adenohypophysial cAMP content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366880"}
{"pmid": "4366881", "title": "Platelet glucose-6-phosphatase activity in patients with von Gierke's disease and their parents.", "content": "Platelet glucose-6-phosphatase activity in patients with von Gierke's disease and their parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366881"}
{"pmid": "4366882", "title": "Lecithin:cholesterol acyltransferase and plasma proteins in liver diseases.", "content": "Lecithin:cholesterol acyltransferase and plasma proteins in liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366882"}
{"pmid": "4366883", "title": "The binding of indocyanine green and other organic anions to serum proteins in liver diseases.", "content": "The binding of indocyanine green and other organic anions to serum proteins in liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366883"}
{"pmid": "4366886", "title": "Investigations on the oncogenic activity for the chick embryo of ribonucleic acid (RNA) extracted from fowl sarcoma induced by the Carr strain (Zilber) of Rous virus.", "content": "Investigations on the oncogenic activity for the chick embryo of ribonucleic acid (RNA) extracted from fowl sarcoma induced by the Carr strain (Zilber) of Rous virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366886"}
{"pmid": "4366887", "title": "Association between production of infectious virus and chromosomal aberrations in carcinomatous human cells (HeLa) persistently infected with Papova virus SV40.", "content": "Association between production of infectious virus and chromosomal aberrations in carcinomatous human cells (HeLa) persistently infected with Papova virus SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366887"}
{"pmid": "4366888", "title": "Mitochondrial functions under hypoxic conditions. The steady states of cytochrome c reduction and of energy metabolism.", "content": "Mitochondrial functions under hypoxic conditions. The steady states of cytochrome c reduction and of energy metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366888"}
{"pmid": "4366889", "title": "The effect of temperature on the primary reaction of chloroplast photosystem II. Evidence for a temperature-dependent back reaction.", "content": "The effect of temperature on the primary reaction of chloroplast photosystem II. Evidence for a temperature-dependent back reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366889"}
{"pmid": "4366890", "title": "Identification of ubiquinone as the secondary electron acceptor in the photosynthetic apparatus of Chromatium vinosum.", "content": "Identification of ubiquinone as the secondary electron acceptor in the photosynthetic apparatus of Chromatium vinosum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366890"}
{"pmid": "4366891", "title": "Light activation of phosphodiesterase activity in retinal rod outer segments.", "content": "Light activation of phosphodiesterase activity in retinal rod outer segments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366891"}
{"pmid": "4366892", "title": "EPR studies by 57Fe isotopic substitution on the nature of an unknown electron acceptor in Azotobacter vinelandii phosphorylating particles.", "content": "EPR studies by 57Fe isotopic substitution on the nature of an unknown electron acceptor in Azotobacter vinelandii phosphorylating particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366892"}
{"pmid": "4366893", "title": "The synthesis of 3-deoxy-4-O-methyl-D-arabino-2-heptulosonic acid and its behaviour in the Warren reaction.", "content": "The synthesis of 3-deoxy-4-O-methyl-D-arabino-2-heptulosonic acid and its behaviour in the Warren reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366893"}
{"pmid": "4366894", "title": "Studies on dextrans and dextranases. XI. The structure of a dextran elaborated by Leuconostoc mesenteroides NRRL B-1299.", "content": "Studies on dextrans and dextranases. XI. The structure of a dextran elaborated by Leuconostoc mesenteroides NRRL B-1299.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366894"}
{"pmid": "4366895", "title": "A synthesis of (plus or minus)-myo-inositol 1-phosphate.", "content": "A synthesis of (plus or minus)-myo-inositol 1-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366895"}
{"pmid": "4366896", "title": "Alkaline sucrose gradient sedimentation studies of DNA from HeLa S3 cells exposed to methyl methanesulphonate or methylazoxymethanol acetate.", "content": "Alkaline sucrose gradient sedimentation studies of DNA from HeLa S3 cells exposed to methyl methanesulphonate or methylazoxymethanol acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366896"}
{"pmid": "4366897", "title": "The determination of metallic elements in wastes and waters with the graphite furnace.", "content": "The determination of metallic elements in wastes and waters with the graphite furnace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366897"}
{"pmid": "4366898", "title": "Using primates in medical reseach. 2. Recent comparative research. Cancer--a general review.", "content": "Using primates in medical reseach. 2. Recent comparative research. Cancer--a general review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366898"}
{"pmid": "4366900", "title": "Using primates in medical research. 2. Recent comparative research. Communicable diseases: hazards for man and models for research.", "content": "Using primates in medical research. 2. Recent comparative research. Communicable diseases: hazards for man and models for research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366900"}
{"pmid": "4366899", "title": "Monkey cell cultures in virology.", "content": "Monkey cell cultures in virology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366899"}
{"pmid": "4366901", "title": "Smallpox and monkeypox in primates.", "content": "Smallpox and monkeypox in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366901"}
{"pmid": "4366902", "title": "Using primates in medical research. 1. Husbandry and technology. New World monkeys.", "content": "Using primates in medical research. 1. Husbandry and technology. New World monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366902"}
{"pmid": "4366904", "title": "Trophic functions of the neuron. VI. Other trophic systems. Neurotrophic regulation at the neuromuscular junction.", "content": "Trophic functions of the neuron. VI. Other trophic systems. Neurotrophic regulation at the neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366904"}
{"pmid": "4366905", "title": "Trophic interactions in the mammalian central nervous system.", "content": "Trophic interactions in the mammalian central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366905"}
{"pmid": "4366903", "title": "Brain and meningeal infections in children. Radiological considerations.", "content": "Brain and meningeal infections in children. Radiological considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366903"}
{"pmid": "4366908", "title": "Some properties of embryonic mitochondria of the loach.", "content": "Some properties of embryonic mitochondria of the loach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366908"}
{"pmid": "4366909", "title": "The relationship between chromosomal aberrations, survival and DNA repair in tumour cell lines of differential sensitivity to X-rays and sulphur mustard.", "content": "The relationship between chromosomal aberrations, survival and DNA repair in tumour cell lines of differential sensitivity to X-rays and sulphur mustard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366909"}
{"pmid": "4366914", "title": "Persistence of Adenovirus 5 in guinea pigs.", "content": "Persistence of Adenovirus 5 in guinea pigs. One intracardiac inoculation of adenovirus 5 in guinea pigs leads to virus persistence in different organs, viz., 5 days in lungs and liver, 14 days in blood and lymph nodes, and 56 days or more in the spleen. After cultivation of tissue cells for 1 week, virus was recovered from blood, lymph nodes, or spleen lymphocytes, but virus could be detected directly in cells only when organs were removed within 48 h of inoculation. To determine how the virus persisted in low concentrations and as a latent infection, spleens were primarily selected for study by three techniques: homogenization of spleens, suspended Maitland fragment cultures, and in vitro cultivation of spleen cells. The last procedure showed virus in fibroblast-like cells (probably macrophages or reticuloendothelial cells) for 56 days after infection of guinea pigs. With other methods, the virus was found only within the first 2 days after inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366914"}
{"pmid": "4366907", "title": "Biomolecules from HCN.", "content": "Biomolecules from HCN.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366907"}
{"pmid": "4366916", "title": "Reactivity of envelope, capsid, and soluble antigens of Herpesvirus hominis types 1 and 2 in the indirect hemagglutination test.", "content": "Reactivity of envelope, capsid, and soluble antigens of Herpesvirus hominis types 1 and 2 in the indirect hemagglutination test. Envelope, capsid, and soluble antigens of Herpesvirus hominis (HVH) types 1 and 2 were compared to crude antigens (disrupted HVH-infected cells) for potency, type-specificity, and diagnostic value in the indirect hemagglutination (IHA) test. The envelope appeared to be the predominant component reacting in the IHA test, but recurrent HVH infections increased the reactivity of human sera with capsid antigens. The soluble antigens reacted in the IHA test with HVH immune animal sera, but very few convalescent-phase human sera showed reactivity with soluble antigens. Overall, none of the subunit antigens showed greater type-specificity than did crude antigens in IHA tests with immune animal or convalescent-phase human sera. Recurrent infections with type 1 or type 2 viruses tended to broaden heterotypic reactivity of the patients' sera with both crude and subunit antigens, even in patients showing only a single type of antibody by IHA inhibition. Subunit antigens were no more sensitive than crude antigens in demonstrating significant IHA antibody titer rises for serodiagnosis of herpesvirus infections, and they generally had to be used at lower working dilutions than crude antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366916"}
{"pmid": "4366915", "title": "In vitro cellular immunity to unrelated pathogens in chickens infected with fowlpox virus.", "content": "In vitro cellular immunity to unrelated pathogens in chickens infected with fowlpox virus. Peritoneal macrophages recovered from chickens 15 to 20 days after inoculation with fowlpox virus and showing a delayed hypersensitivity reaction against fowlpox antigens demonstrated an enhanced antimicrobial effect against fowlpox virus as well as unrelated viruses and bacteria. Inoculation of normal chicken macrophage cultures with fowlpox virus resulted in approximately a 200-fold increase in virus titer by 96 h, whereas the virus showed less than a fourfold increase in macrophage cultures from fowlpox-immune chickens. Similarly, the titer of Newcastle disease virus increased by more than 1 log in cultures of normal macrophages, whereas the titer decreased by approximately 1 log after infection of fowlpox-immune macrophages. Vaccinia, vesicular stomatitis, and herpes simplex viruses, which are not natural pathogens of chickens, failed to replicate in cultures of either normal or fowlpox-immune macrophages. By using Salmonella gallinarum, it was further demonstrated that the antimicrobial activity of fowlpox-immune macrophages encompassed not only nonspecific viruses but also bacteria. Infection of normal macrophages with Salmonella resulted in intracellular replication of the organism between 0 and 24 h as determined by microscope examination and viable bacteria counts. In contrast, cultures of fowlpox-immune macrophages failed to show an increase in intracellular organisms and showed a marked decrease in viable bacteria. In conclusion, these studies clearly showed that cellular immunity, previously demonstrated in mammalian species, develops in chickens after infection with fowlpox virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366915"}
{"pmid": "4366917", "title": "Production of chemotactic factor and lymphotoxin by human leukocytes stimulated with Herpes simplex virus.", "content": "Production of chemotactic factor and lymphotoxin by human leukocytes stimulated with Herpes simplex virus. Peripheral blood leukocytes (PBL) of 41 subjects were tested for their ability to be stimulated by herpes simplex virus antigens as measured by [(3)H]thymidine incorporation and lymphokine production (i.e., lymphocyte-derived chemotactic factor and lymphotoxin). The PBL of seronegative subjects failed to respond to viral antigens as measured by stimulation or lymphokine production. In contrast, PBL from seropositive subjects without clinical lesions of herpes labialis were stimulated by herpes simplex virus antigens and produced lymphokines. PBL from seropositive patients with clinical lesions of herpes labialis also produced lymphokines, but [(3)H]thymidine incorporation was slightly depressed. These findings suggest that lymphocytes from patients with a recent herpes simplex virus infection may respond less vigorously to in vitro stimulation by herpes antigens, but our study fails to show any basic defect in the responsiveness of the lymphocytes to account for recurrent herpetic episodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366917"}
{"pmid": "4366906", "title": "Aspects of the geologic history of seawater.", "content": "Aspects of the geologic history of seawater.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366906"}
{"pmid": "4366918", "title": "Oxygen uptake by Treponema pallidum.", "content": "Oxygen uptake by Treponema pallidum. Virulent Treponema pallidum has been shown to consume O(2) at a rate similar to that of the known aerobic spirochaete, Leptospira. Such O(2) uptake is cyanide sensitive, indicating a functioning cytochrome oxidase. Inhibition of O(2) uptake by azide, chlorpromazine, and amytal further suggests a functioning electron transport system for the oxidation of nicotinamide adenine dinucleotide (reduced) to O(2). Evidence is consistent with the probability that this terminal electron-transport system is coupled to oxidative phosphorylation. The potential significance of these findings is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366918"}
{"pmid": "4366919", "title": "Escherichia coli enterotoxin-induced steroidogenesis in cultured adrenal tumor cells.", "content": "Escherichia coli enterotoxin-induced steroidogenesis in cultured adrenal tumor cells. A heat-labile, Pronase-sensitive factor has been partially purified from cell-free culture filtrates of enterotoxigenic Escherichia coli. The partially purified factor contains both protein and carbohydrate moieties and appears to be E. coli enterotoxin (ECT). ECT binds to cultured adrenal tumor cells rapidly and irreversibly leads to adenosine 3', 5'-cyclic monophosphate formation and steroidogenesis after a 60-min lag phase. Further studies indicate that it interacts with the cholera toxin receptor site on adrenal cells rather than the adrenocorticotropin receptor to activate adenyl cyclase. Mixed gangliosides block stimulation of steroidogenesis in response to both E. coli and cholera enterotoxin. In contrast to adrenocorticotropin, ECT has no additive effect on cholera toxin-induced steroidogenesis. The protein moiety of ECT is similar to cholera enterotoxin because horse serum anticholeragenoid prevented stimulation of steroidogenesis by either enterotoxin. Cultured adrenal cells provide a quantitative assay system that has facilitated the purification and characterization of E. coli enterotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366919"}
{"pmid": "4366921", "title": "Growth of murine cytomegalovirus in a heterologous cell system and its enhancement by 5-iodo-2'-deoxyuridine.", "content": "Growth of murine cytomegalovirus in a heterologous cell system and its enhancement by 5-iodo-2'-deoxyuridine. Mouse cytomegalovirus replicated in rabbit kidney cultures, a cell system of nonrodent origin. However, the sensitivity of these cultures, and the yields of virus therefrom, were lower than those of mouse cultures. Although a cytopathic effect developed in rabbit kidney cultures inoculated with sufficient amounts of the virus, such cultures were unsatisfactory for plaque assay. This was also true when rabbit fibroblast cultures were used, even though the murine cytomegalovirus replicated much better in mouse fibroblasts than in mouse kidney cultures, the latter of which contained extensive areas of epithelial cells. Viral growth in rabbit kidney cells was considerably enhanced when those cells had been initiated and grown in the presence of 5-iodo-2'-deoxyuridine; not only were the viral titers increased, but also the clarity and distinctness of the inclusion bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366921"}
{"pmid": "4366920", "title": "Comparison of techniques and immunoreagents used for indirect immunofluorescence and immunoperoxidase identification of enteroviruses.", "content": "Comparison of techniques and immunoreagents used for indirect immunofluorescence and immunoperoxidase identification of enteroviruses. Peroxidase-conjugated antibodies were found to be as sensitive as those conjugated to fluorescein-isothiocyanate (FITC) for identification of selected enterovirus types by the indirect technique. Peroxidase conjugates, however, were found to give fewer nonspecific reactions. The reasons for the higher specificity of the immunoperoxidase technique appear to be related to the relative size, charge, and uniformity of the preparations. Monomers of peroxidase-conjugated globulin are larger than those of FITC conjugates, but the latter readily form aggregates. This was shown by chromatography on Sepharose 6B columns: various FITC-conjugated globulins eluted before those conjugated to peroxidase and before (125)I-labeled immunoglobulin G. The net charge of the conjugates was determined by adsorption to ion-exchange columns. FITC-labeled globulins had a negative net charge, eluting at pH 5.1 from diethylamino-ethyl-Sephadex A-50 columns. Peroxidase conjugates were not retained by either cationic or anionic exchangers at pH values ranging from 4.0 to 10.5. Further, the fluorescein/protein ratios of FITC conjugates from different commercial sources and of those prepared in the laboratory were found to be variable; higher fluorescein/protein ratios (>2:1) give a higher degree of nonspecific reactions, whereas the peroxidase/protein ratio does not appear to affect specificity. These characteristics of peroxidase conjugates make the immunoperoxidase technique easier to standardize and more reliable for enterovirus identification than the immunofluorescence technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366920"}
{"pmid": "4366923", "title": "Origin and biological role of molecular asymmetry.", "content": "Origin and biological role of molecular asymmetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366923"}
{"pmid": "4366925", "title": "Editorial: Tempest in the chickenpot.", "content": "Editorial: Tempest in the chickenpot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366925"}
{"pmid": "4366926", "title": "Benign tumors of the hand.", "content": "Benign tumors of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366926"}
{"pmid": "4366928", "title": "Molecular mechanisms of temperature compensation in poikilotherms.", "content": "Molecular mechanisms of temperature compensation in poikilotherms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366928"}
{"pmid": "4366929", "title": "Fetal hamartoma of the kidney--a benign tumour to be distinguished from Wilms' tumour.", "content": "Fetal hamartoma of the kidney--a benign tumour to be distinguished from Wilms' tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366929"}
{"pmid": "4366931", "title": "Complementation of adeno-associated satellite viral antigens and infectious DNA by temperature-sensitive mutants of herpes simplex virus.", "content": "Complementation of adeno-associated satellite viral antigens and infectious DNA by temperature-sensitive mutants of herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366931"}
{"pmid": "4366930", "title": "The host DNA sequences in different populations of serially passaged SV40.", "content": "The host DNA sequences in different populations of serially passaged SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366930"}
{"pmid": "4366932", "title": "Studies on action mechanisms of a possible false cholinergic transmitter, (2-hydroxyethyl) methyldiethylammonium.", "content": "Studies on action mechanisms of a possible false cholinergic transmitter, (2-hydroxyethyl) methyldiethylammonium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366932"}
{"pmid": "4366933", "title": "A pilgrim's progress in cancer research, 1918 to 1974: autobiographical essay.", "content": "A pilgrim's progress in cancer research, 1918 to 1974: autobiographical essay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366933"}
{"pmid": "4366934", "title": "Blood glucose levels and gluconeogenesis in animals bearing transplantable tumors.", "content": "Blood glucose levels and gluconeogenesis in animals bearing transplantable tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366934"}
{"pmid": "4366935", "title": "The presence of the Epstein-Barr viral genome in human lymphoblastoid B-cell lines and its absence in a myeloma cell line.", "content": "The presence of the Epstein-Barr viral genome in human lymphoblastoid B-cell lines and its absence in a myeloma cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366935"}
{"pmid": "4366936", "title": "Alveolar cell carcinoma-like antigen and antibodies in patients with alveolar cell carcinoma and other cancers.", "content": "Alveolar cell carcinoma-like antigen and antibodies in patients with alveolar cell carcinoma and other cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366936"}
{"pmid": "4366937", "title": "Mitochondrial protein content and enzyme activity of Reuber hepatoma H-351.", "content": "Mitochondrial protein content and enzyme activity of Reuber hepatoma H-351.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366937"}
{"pmid": "4366938", "title": "Inhibition of subcutaneously growing line 1 carcinomas due to metastatic spread.", "content": "Inhibition of subcutaneously growing line 1 carcinomas due to metastatic spread.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366938"}
{"pmid": "4366939", "title": "Proceedings: Heterogeneity of carcinoembryonic antigen.", "content": "Proceedings: Heterogeneity of carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366939"}
{"pmid": "4366940", "title": "Estrogen excretion in a case of theca-granulosa cell tumor.", "content": "Estrogen excretion in a case of theca-granulosa cell tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366940"}
{"pmid": "4366941", "title": "Prolactin binding to rat mammary tumor tissue.", "content": "Prolactin binding to rat mammary tumor tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366941"}
{"pmid": "4366942", "title": "Anterolateral hypothalamic deafferentation prevents compensatory hypersecretion of ACTH following adrenalectomy in the rat.", "content": "Anterolateral hypothalamic deafferentation prevents compensatory hypersecretion of ACTH following adrenalectomy in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366942"}
{"pmid": "4366943", "title": "Isolation and characterization of a neutral deoxyribonuclease from the testes of the crab Cancer pagurus.", "content": "Isolation and characterization of a neutral deoxyribonuclease from the testes of the crab Cancer pagurus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366943"}
{"pmid": "4366944", "title": "Different expressions of cooperativity in the kinetics of two forms of cytoplasmic malic dehydrogenase.", "content": "Different expressions of cooperativity in the kinetics of two forms of cytoplasmic malic dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366944"}
{"pmid": "4366946", "title": "Fabry's disease: specific inclusions found on electron microscopy of fibroblast cultures.", "content": "Fabry's disease: specific inclusions found on electron microscopy of fibroblast cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366946"}
{"pmid": "4366945", "title": "Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.", "content": "Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366945"}
{"pmid": "4366947", "title": "DNA-synthesis in the spleen of mice after whole-body X-irradiation and its modification by 5-hydroxytryptamine and NADH.", "content": "DNA-synthesis in the spleen of mice after whole-body X-irradiation and its modification by 5-hydroxytryptamine and NADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366947"}
{"pmid": "4366948", "title": "Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.", "content": "Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366948"}
{"pmid": "4366954", "title": "5'-Adenylylation and 5'-uridylation of N-acetyl tyrosine ethyl ester: a general synthesis of 5'-nucleotidylated tyrosyl residues.", "content": "5'-Adenylylation and 5'-uridylation of N-acetyl tyrosine ethyl ester: a general synthesis of 5'-nucleotidylated tyrosyl residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366954"}
{"pmid": "4366955", "title": "Metabolism of glycol-derived lipids in Novikoff hepatomas.", "content": "Metabolism of glycol-derived lipids in Novikoff hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366955"}
{"pmid": "4366956", "title": "Nucleotide sequences at the cleavage sites of two restriction endonucleases from Hemophilus parainfluenzae.", "content": "Nucleotide sequences at the cleavage sites of two restriction endonucleases from Hemophilus parainfluenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366956"}
{"pmid": "4366957", "title": "The length of repetitive sequences of monkey cell and salmon sperm DNA.", "content": "The length of repetitive sequences of monkey cell and salmon sperm DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366957"}
{"pmid": "4366958", "title": "Decreased basal cyclic adenosine 3',5'-monophosphate levels in Morris hepatoma 5123 t.c. (h).", "content": "Decreased basal cyclic adenosine 3',5'-monophosphate levels in Morris hepatoma 5123 t.c. (h).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366958"}
{"pmid": "4366960", "title": "TSH regulation of cAMP-dependent protein kinase activity in the thyroid.", "content": "TSH regulation of cAMP-dependent protein kinase activity in the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366960"}
{"pmid": "4366959", "title": "Stimulation of DNA polymerase activity by the combination of p-hydroxymercuribenzoate and dithiothreitol.", "content": "Stimulation of DNA polymerase activity by the combination of p-hydroxymercuribenzoate and dithiothreitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366959"}
{"pmid": "4366962", "title": "A proposed hydrogen transfer function for cytochrome c.", "content": "A proposed hydrogen transfer function for cytochrome c. Outlines of proposed mechanisms for cytochrome c oxidoreduction are presented which differ in detail from those previously published. The mechanisms, while accommodating the fact that cytochrome c is a net electron acceptor and donor in its catalytic cycle, dictate that the enzyme catalyses hydrogen transfer. It is shown that the mechanism of cytochrome c reduction fulfills a recent proposal that the transition state is an analogue of the structure of ferricytochrome c(2). The implications of a hydrogen transfer role of cytochrome c are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366962"}
{"pmid": "4366961", "title": "Structure-function correlations of formylmethionine transfer RNA.", "content": "Structure-function correlations of formylmethionine transfer RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366961"}
{"pmid": "4366964", "title": "Structure of cell wall and exocellular mannans from the yeast Hansenula holstii. I. Mannans produced in phosphate-containing medium.", "content": "Structure of cell wall and exocellular mannans from the yeast Hansenula holstii. I. Mannans produced in phosphate-containing medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366964"}
{"pmid": "4366965", "title": "Direct measurement of electric current generation by cytochrome oxidase, H+-ATPase and bacteriorhodopsin.", "content": "Direct measurement of electric current generation by cytochrome oxidase, H+-ATPase and bacteriorhodopsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366965"}
{"pmid": "4366963", "title": "Preferential inhibition of the growth of virus-transformed cells in culture by rifazone-82, a new rifamycin derivative.", "content": "Preferential inhibition of the growth of virus-transformed cells in culture by rifazone-82, a new rifamycin derivative. Rifazone-8(2), a new rifamycin derivative, is shown to preferentially inhibit the growth of virus-transformed chick cells in culture. Macromolecular synthesis and glucose uptake of transformed cells are also appreciably decreased in the presence of low concentrations of rifazone-8(2) where the normal cells appear unaffected. While rifazone-8(2) is shown to be a selective inhibitor of RNA-directed DNA polymerase in vitro, its action on the growth of transformed cells may involve some other mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366963"}
{"pmid": "4366966", "title": "Effects of nucleotides, hormones, ions, and 1,25-dihydroxycholecalciferon on 1,25-dihydroxycholecalciferol production in isolated chick renal tubules.", "content": "Effects of nucleotides, hormones, ions, and 1,25-dihydroxycholecalciferon on 1,25-dihydroxycholecalciferol production in isolated chick renal tubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366966"}
{"pmid": "4366968", "title": "Preparation of cell lysate for separation of polyoma DNA from cellular DNA by sedimentation velocity.", "content": "Preparation of cell lysate for separation of polyoma DNA from cellular DNA by sedimentation velocity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366968"}
{"pmid": "4366967", "title": "Maintenance of pregnancy in rats on deficient diets.", "content": "Maintenance of pregnancy in rats on deficient diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366967"}
{"pmid": "4366970", "title": "Virus-augmented tumor transplantation antigens: evidence for a Helper antigen mechanism.", "content": "Virus-augmented tumor transplantation antigens: evidence for a Helper antigen mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366970"}
{"pmid": "4366969", "title": "Reduced transplantability of syngeneic tumors in rats immunized with allogeneic tumors.", "content": "Reduced transplantability of syngeneic tumors in rats immunized with allogeneic tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366969"}
{"pmid": "4366971", "title": "Occupational lung cancer among copper smelters.", "content": "Occupational lung cancer among copper smelters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366971"}
{"pmid": "4366972", "title": "Induction of neurogenic tumors in C3HeB-FeJ mice by nitrosourea derivatives: observations by light microscopy, tissue culture, and electron microscopy.", "content": "Induction of neurogenic tumors in C3HeB-FeJ mice by nitrosourea derivatives: observations by light microscopy, tissue culture, and electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366972"}
{"pmid": "4366974", "title": "Frequency dependence of dual negative feedback control of secretion of sympathetic neurotransmitter in guinea-pig vas deferens.", "content": "Frequency dependence of dual negative feedback control of secretion of sympathetic neurotransmitter in guinea-pig vas deferens. The secretion of sympathetic neurotransmitter in guinea-pig vas deferens appears to be normally controlled by two different mechanisms, one dependent and one independent of prostaglandin E. The efficiency of both control systems, as well as of exogenous prostaglandin E(2), is inversely related to nerve stimulation frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366974"}
{"pmid": "4366975", "title": "Basal cell adenoma of intraoral minor salivary gland origin.", "content": "Basal cell adenoma of intraoral minor salivary gland origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366975"}
{"pmid": "4366973", "title": "Inhibition by diuretics of cyclic 3',5'-AMP-dependent protein kinase from toad bladder epithelium.", "content": "Inhibition by diuretics of cyclic 3',5'-AMP-dependent protein kinase from toad bladder epithelium. 1. A cAMP-dependent protein kinase enzyme has been isolated from toad bladder epithelium.2. This enzyme catalyses the phosphorylation of histones; a reaction stimulated by 0.1 muM cAMP.3. Activity of this enzyme in the presence of 0.1 muM cAMP was significantly inhibited by 100 muM mercuderamide, bumetanide and frusemide. A small, though statistically insignificant inhibition was seen with the same concentrations of hydrochlorothiazide and ethacrynic acid.4. The half maximal inhibition was achieved with mercuderamide, 5 muM, and with frusemide and bumetanide 600 muM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366973"}
{"pmid": "4366977", "title": "The oncogenicity of Epstein-Barr virus.", "content": "The oncogenicity of Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366977"}
{"pmid": "4366976", "title": "Bronchoscopic diagnosis of cytomegalovirus infection.", "content": "Bronchoscopic diagnosis of cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366976"}
{"pmid": "4366978", "title": "Studies on 1-beta-D-arabinofuranosyl-cytosine (Ara-C) resistant mutants of Chinese hamster fibroblasts. II. High resistance to Ara-C as a genetic marker for cellular hybridization.", "content": "Studies on 1-beta-D-arabinofuranosyl-cytosine (Ara-C) resistant mutants of Chinese hamster fibroblasts. II. High resistance to Ara-C as a genetic marker for cellular hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366978"}
{"pmid": "4366979", "title": "Cell surface interactions with concanavalin A. Location of bound radiolabeled lectin.", "content": "Cell surface interactions with concanavalin A. Location of bound radiolabeled lectin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366979"}
{"pmid": "4366981", "title": "A differential chemotactic response of slime mould amoebae to regions of the early amphibian embryo.", "content": "A differential chemotactic response of slime mould amoebae to regions of the early amphibian embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366981"}
{"pmid": "4366982", "title": "Serological studies of normal and leukemic cats in a multiple-case leukemia cluster.", "content": "Serological studies of normal and leukemic cats in a multiple-case leukemia cluster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366982"}
{"pmid": "4366980", "title": "Low resistance junctions between normal and between virus transformed fibroblasts in tissue culture.", "content": "Low resistance junctions between normal and between virus transformed fibroblasts in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366980"}
{"pmid": "4366983", "title": "Herpesviruses and cervical cancer.", "content": "Herpesviruses and cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366983"}
{"pmid": "4366984", "title": "Perspectives on the epidemiology of cervical cancer with special reference to the herpesvirus hypothesis.", "content": "Perspectives on the epidemiology of cervical cancer with special reference to the herpesvirus hypothesis. Epidemiological considerations with regard to mortality statistics and incidence rates for cervical cancer are discussed and recent data are summarized.  The unresolved problem of the nature of the relationship between cervical dysplasia and carcinoma in situ with invasive cervical cancer is considered.  A summary is made of data on time trends in the incidence of cervical cancer and of the details of studies on the biological behavior of cervical carcinoma in situ.  Coital/marital and penile factors in the etiology of cervical cancer are reviewed, and the herpesvirus hypothesis is evaluated in light of methodological considerations.  Finally, a major new collaborative prospective test of the herpesvirus hypothesis is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366984"}
{"pmid": "4366985", "title": "Epidemiological studies relating genital herpetic infection to cervical carcinoma.", "content": "Epidemiological studies relating genital herpetic infection to cervical carcinoma. Epidemiological studies relating genital herpetic infection to cervical carcinoma are reviewed.  The high frequency of herpes simplex virus type 2 (HSV-2) antibodies in young women (21 years or younger) with cervical carcinoma in situ and in women with dysplasia or carcinoma in situ, matched for various sexual attributes to control women, provide support for a causal relation.  However, various laboratory, histopathological, and statistical problems associated with all epidemiological studies do not yet permit a firm conclusion as to the etiological role to the genital virus in cervical carcinogenesis.  With the use of herpes-related cancer antigens or purified HSV-2 type-specific antigens, and with the possible development of protective HSV-2 vaccines, the application of epidemiological approaches may be necessary to provide the most finite evidence of causality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366985"}
{"pmid": "4366987", "title": "Biochemical approaches to detection of herpes simplex virus type 2 in cervical carcinoma.", "content": "Biochemical approaches to detection of herpes simplex virus type 2 in cervical carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366987"}
{"pmid": "4366986", "title": "A nonhuman primate model for the study of the cervical oncogenic potential of herpes simplex virus type 2.", "content": "A nonhuman primate model for the study of the cervical oncogenic potential of herpes simplex virus type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366986"}
{"pmid": "4366988", "title": "Discussion of case-control study of Hodgkin's disease.", "content": "Discussion of case-control study of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366988"}
{"pmid": "4366989", "title": "Nasopharyngeal carcinoma: recent studies and outlook for a viral etiology.", "content": "Nasopharyngeal carcinoma: recent studies and outlook for a viral etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366989"}
{"pmid": "4366990", "title": "Antibodies to herpes group viruses in patients with nasopharyngeal and other head and neck cancers.", "content": "Antibodies to herpes group viruses in patients with nasopharyngeal and other head and neck cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366990"}
{"pmid": "4366991", "title": "Antibody levels to infectious agents other than Epstein-Barr virus in Burkitt's lymphoma patients.", "content": "Antibody levels to infectious agents other than Epstein-Barr virus in Burkitt's lymphoma patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366991"}
{"pmid": "4366992", "title": "Immunological reactions to tumor-associated antigens in Burkitts lymphoma and other lymphomas.", "content": "Immunological reactions to tumor-associated antigens in Burkitts lymphoma and other lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366992"}
{"pmid": "4366994", "title": "Animal models: herpesvirus saimiri, a nonhuman primate model for herpesvirus-associated neoplasia of man.", "content": "Animal models: herpesvirus saimiri, a nonhuman primate model for herpesvirus-associated neoplasia of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366994"}
{"pmid": "4366993", "title": "Epstein-Barr virus DNA in Hodgkin's disease, American Burkitt's lymphoma, and other human tumors.", "content": "Epstein-Barr virus DNA in Hodgkin's disease, American Burkitt's lymphoma, and other human tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366993"}
{"pmid": "4366995", "title": "Epstein-Barr virus: one or a family of viruses.", "content": "Epstein-Barr virus: one or a family of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366995"}
{"pmid": "4366997", "title": "DNA and nucleoprotein changes in liver and tumor nuclei after irradiation.", "content": "DNA and nucleoprotein changes in liver and tumor nuclei after irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366997"}
{"pmid": "4366998", "title": "Eicosatrienoic acid omega9 in serum lipids of patients with hepatocellular carcinoma.", "content": "Eicosatrienoic acid omega9 in serum lipids of patients with hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4366998"}
{"pmid": "4367000", "title": "Studies on the dense pre-beta-lipoprotein of human serum.", "content": "Studies on the dense pre-beta-lipoprotein of human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367000"}
{"pmid": "4367001", "title": "3,4-Methylene hexanedioic acid--a previously unknown compound in human urine.", "content": "3,4-Methylene hexanedioic acid--a previously unknown compound in human urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367001"}
{"pmid": "4367006", "title": "Direct contact between a neuron and soma and myocardial cells; an electronmicroscopic finding in the sinus venosus of the turtle heart.", "content": "Direct contact between a neuron and soma and myocardial cells; an electronmicroscopic finding in the sinus venosus of the turtle heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367006"}
{"pmid": "4367012", "title": "Antiviral compounds. XVI. p-Alkylthiophenylglyoxals and their derivatives.", "content": "Antiviral compounds. XVI. p-Alkylthiophenylglyoxals and their derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367012"}
{"pmid": "4367004", "title": "Cell culture of the endocrine pancreas of the mouse in chemically defined media.", "content": "Cell culture of the endocrine pancreas of the mouse in chemically defined media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367004"}
{"pmid": "4367021", "title": "Femoral cortical erosions and osteoarthrosis of the knee with chondrocalcinosis. An anatomo-radiological study of two cases.", "content": "Femoral cortical erosions and osteoarthrosis of the knee with chondrocalcinosis. An anatomo-radiological study of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367021"}
{"pmid": "4367029", "title": "The effect of drugs influencing the level of cyclic AMP on angiotensin hyperglycaemia in rabbits.", "content": "The effect of drugs influencing the level of cyclic AMP on angiotensin hyperglycaemia in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367029"}
{"pmid": "4367028", "title": "Clindamycin phosphate in severe infections mainly caused by Bacteroides fragilis: clinical and microbiological evaluation.", "content": "Clindamycin phosphate in severe infections mainly caused by Bacteroides fragilis: clinical and microbiological evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367028"}
{"pmid": "4367030", "title": "Seroepidemiology of herpesvirus type Epstein-Barr in blood donors from communities around Lyon.", "content": "Seroepidemiology of herpesvirus type Epstein-Barr in blood donors from communities around Lyon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367030"}
{"pmid": "4367031", "title": "Occurrence of respiratory illness due to an atypical strain of adenovirus type 11 during a large outbreak in Spanish military recruits.", "content": "Occurrence of respiratory illness due to an atypical strain of adenovirus type 11 during a large outbreak in Spanish military recruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367031"}
{"pmid": "4367032", "title": "Study of Japanese encephalitis virus in Chiangmia Valley, Thailand. V. Animal infections.", "content": "Study of Japanese encephalitis virus in Chiangmia Valley, Thailand. V. Animal infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367032"}
{"pmid": "4367033", "title": "Study of Japanese encephalitis virus in Chiangmia Valley, Thailand. VI. Summary and conclusions.", "content": "Study of Japanese encephalitis virus in Chiangmia Valley, Thailand. VI. Summary and conclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367033"}
{"pmid": "4367034", "title": "Use of the delayed brain scan in differentiating calvarial from cerebral lesions.", "content": "Use of the delayed brain scan in differentiating calvarial from cerebral lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367034"}
{"pmid": "4367035", "title": "Further studies on chemical closure of the Fallopian tubes in the monkey.", "content": "Further studies on chemical closure of the Fallopian tubes in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367035"}
{"pmid": "4367036", "title": "A fluorometric kinetic method for creatine in urine.", "content": "A fluorometric kinetic method for creatine in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367036"}
{"pmid": "4367037", "title": "Purification and further characterization of three DNA polymerases of rat Ascites hepatoma cells.", "content": "Purification and further characterization of three DNA polymerases of rat Ascites hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367037"}
{"pmid": "4367038", "title": "Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizing enzyme system. 3.", "content": "Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizing enzyme system. 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367038"}
{"pmid": "4367039", "title": "Inhibition of 2-deoxy-D-glucose transport by theophylline, caffeine and papaverine in alveolar macrophages.", "content": "Inhibition of 2-deoxy-D-glucose transport by theophylline, caffeine and papaverine in alveolar macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367039"}
{"pmid": "4367077", "title": "Antibody formation after irradiation and its cellular background.", "content": "Antibody formation after irradiation and its cellular background.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367077"}
{"pmid": "4367104", "title": "Anti-tumor activity in regression fluid.", "content": "Anti-tumor activity in regression fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367104"}
{"pmid": "4367108", "title": "Endocrine action during insect growth.", "content": "Endocrine action during insect growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367108"}
{"pmid": "4367109", "title": "Nerve growth factor and insulin: evidence of similarities in structure, function, and mechanism of action.", "content": "Nerve growth factor and insulin: evidence of similarities in structure, function, and mechanism of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367109"}
{"pmid": "4367107", "title": "The lysosome as a mediator of hormone action.", "content": "The lysosome as a mediator of hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367107"}
{"pmid": "4367111", "title": "Microtubule proteins in the nerve growth factor mediated response. Interaction between the nerve growth factor and its target cells.", "content": "Microtubule proteins in the nerve growth factor mediated response. Interaction between the nerve growth factor and its target cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367111"}
{"pmid": "4367112", "title": "Insulin secreting pancreatic adenoma demonstrated by selective angiography.", "content": "Insulin secreting pancreatic adenoma demonstrated by selective angiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367112"}
{"pmid": "4367110", "title": "Heterogeneity of peptide hormones.", "content": "Heterogeneity of peptide hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367110"}
{"pmid": "4367115", "title": "Preparation of DNA-splitting activities yielding 3'-mononucleotides from the sponge Verongia aerophoba.", "content": "Preparation of DNA-splitting activities yielding 3'-mononucleotides from the sponge Verongia aerophoba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367115"}
{"pmid": "4367105", "title": "Adenocarcinoma of the lung cytologic correlation with histologic types.", "content": "Adenocarcinoma of the lung cytologic correlation with histologic types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367105"}
{"pmid": "4367106", "title": "Cellular changes in the glandular epithelium of patients using IUCD--a source of cytologic error.", "content": "Cellular changes in the glandular epithelium of patients using IUCD--a source of cytologic error.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367106"}
{"pmid": "4367116", "title": "Hydrophobic binding sites in bovine serum albumin and erythrocyte ghost proteins. Study by spin-labelling, paramagnetic fluorescence quenching and chemical modification.", "content": "Hydrophobic binding sites in bovine serum albumin and erythrocyte ghost proteins. Study by spin-labelling, paramagnetic fluorescence quenching and chemical modification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367116"}
{"pmid": "4367120", "title": "Biological properties of two strains of Simian virus 40 isolated from patients with progressive multifocal leukoencephalopathy.", "content": "Biological properties of two strains of Simian virus 40 isolated from patients with progressive multifocal leukoencephalopathy. Biological properties of two strains of simian virus 40 (SV40) from brains of two patients with progressive multifocal leukoencephalopathy (PML) have been compared to those of a standard laboratory strain of SV40. Infectivity of both SV40-PML viruses was resistant to treatment with chloroform, low pH, and 50 C for 120 min. African green monkey kidney and BSC-1 cells were the most sensitive for viral replication, and cytopathology in these cultures was indistinguishable from that caused by SV40. Both viruses formed plaques in these cells. but, in African green monkey kidney cells, strain 1 virus produced plaques measuring 2 mm in diameter whereas strain 2 virus produced pleomorphic plaques varying from 1 to 10 mm in diameter. Hamster cells were not permissive for viral replication, and infection resulted only in viral transformation. Inoculation of human fetal glial cells resulted in a permissive lytic infection of one cell type and a persistent infection with only partial expression of the viral genome in the other. No morphological evidence of transformation was evident in the latter cells. Both strains of SV40-PML viruses were neutralized by commercial anti-SV40 serum, but in reciprocal kinetic neutralization tests differences in K values were noted when each was compared to SV40. Both viruses showed oncogenicity for hamsters, producing undifferentiated sarcomas when injected subcutaneously and choroid plexus papillomas after intracerebral inoculation. All hamster tumor cells contained intranuclear immunofluorescent tumor antigen. This was indistinguishable from SV40 T antigen in reciprocal staining reactions using hamster anti-T antibody induced by the two SV40-PML agents and SV40. These two human agents appear therefore to be new variants of simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367120"}
{"pmid": "4367119", "title": "Comparison of immunofluorescence and isolation techniques in the diagnosis of respiratory viral infections of children.", "content": "Comparison of immunofluorescence and isolation techniques in the diagnosis of respiratory viral infections of children. The immunoflourescent antibody technique (IFAT) and cell culture isolation procedures were compared for their efficiency in the etiological diagnosis of viral respiratory illness in children. Before the IFAT was incorporated as a routine procedure, antisera used in the test were carefully calibrated to insure specificity. A study was then conducted in which 375 nasopharyngeal suctions were investigated by both IFAT and isolation for the presence of parainfluenza virus types 1, 2, and 3, respiratory syncytial, influenza A, and influenza B viruses. Methods already established in our hospital for patient management and specimen collection were not altered for the purposes of the study. The IFAT, as conventionally practiced in the detection of respiratory virus antigens, requires adequate numbers of ciliated epithelial cells. There were 68.5% specimens which contained cells suitable for IFAT, whereas 31.5% had either an insufficient number or inappropriate types of cells and could be used only for virus isolation. Cell-associated immunoglobulins were detected in 16% of those specimens with adequate cells. When all specimens were considered regardless of their cell population, IFAT was inferior to isolation in diagnostic efficiency. However, isolation complemented by IFAT resulted in a statistically significant increase in number of positive virus identifications. Under routine working conditions in a large pediatric hospital, it was found that IFAT could not replace isolation techniques but could, if used in conjunction with isolation, provide a significant overall increase in number of positive diagnoses. The time that the specimen was taken in relation to first symptoms was found to be an important variable with respect to the method most likely to succeed in virus identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367119"}
{"pmid": "4367121", "title": "Hepatocellular localization of fetal antigens during induction of rat liver tumors by 3'-methyl-4-dimethylaminoazobenzene.", "content": "Hepatocellular localization of fetal antigens during induction of rat liver tumors by 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367121"}
{"pmid": "4367122", "title": "Primary neoplasms in dog liver induced by diethylnitrosamine.", "content": "Primary neoplasms in dog liver induced by diethylnitrosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367122"}
{"pmid": "4367123", "title": "Biosynthesis of globoside and Forssman-related glycosphingolipid in mouse adrenal Y-1 tumor cells.", "content": "Biosynthesis of globoside and Forssman-related glycosphingolipid in mouse adrenal Y-1 tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367123"}
{"pmid": "4367124", "title": "The effects of di-butyryl cAMP on enzymatic and metabolic changes in explants of rat mammary tissue.", "content": "The effects of di-butyryl cAMP on enzymatic and metabolic changes in explants of rat mammary tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367124"}
{"pmid": "4367125", "title": "Influence of reserpine-induced depletion of noradrenaline on the negative feed-back mechanism for transmitter release during nerve stimulation.", "content": "Influence of reserpine-induced depletion of noradrenaline on the negative feed-back mechanism for transmitter release during nerve stimulation. 1. The effects of depletion of endogenous noradrenaline by reserpine-pretreatment on [(3)H]-noradrenaline overflow elicited by nerve stimulation were determined in the isolated nerve-muscle preparation of the cat's nictitating membrane.2. Reserpine pretreatment (0.3 mg/kg, s.c., 4 days prior to the experiment) reduced the noradrenaline levels in the smooth muscle of the nictitating membrane to about 10% of the control values while granular retention of [(3)H]-noradrenaline had recovered to nearly 40% of the controls.3. In the reserpine-pretreated tissue the fraction release per shock induced by nerve stimulation was 2.2-fold higher than the value obtained in the untreated tissues. This effect was correlated with the degree of depletion of the noradrenaline stores rather than with the decrease in the response of the effector organ.4. Phenoxybenzamine, 2.9 muM reduced the responses to nerve stimulation to the same extent in control and in reserpine-pretreated tissues. Yet, this concentration of phenoxybenzamine increased by 13-fold the overflow of the labelled transmitter in the controls and only by 3-fold in reserpine-pretreated tissues.5. The decrease in effectiveness of phenoxybenzamine in enhancing transmitter overflow after reserpine-pretreatment appears to be due to the decrease in the total release of the transmitter.6. The results obtained support the view that in reserpine-pretreated tissues decreased transmitter output reduces the activation of the presynaptic alpha-adrenoceptors which mediate the negative feed-back mechanism that regulates transmitter release by nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367125"}
{"pmid": "4367126", "title": "Presynaptic and postsynaptic effects of the venom of the Australian tiger snake at the neuromuscular junction.", "content": "Presynaptic and postsynaptic effects of the venom of the Australian tiger snake at the neuromuscular junction. 1. Crude venom (TSV) from the Australian tiger snake (Notechis scutatus scutatus) has both presynaptic and postsynaptic effects at the neuromuscular junctions of toads.2. TSV (50 mug/ml) rapidly blocked indirectly elicited muscle twitches without affecting the compound action potential in the sciatic nerve or twitches elicited by direct stimulation.3. Low concentrations of the venom (1-10 mug/ml) reduced the amplitude of miniature endplate potentials (m.e.p.ps) and inhibited the depolarization of muscle fibres normally caused by carbachol. It was concluded that a fraction of the venom binds to acetylcholine receptors.4. The frequency of m.e.p.ps was at first increased by TSV at a concentration of 1 mug/ml. Occasional, high frequency ;bursts' of m.e.p.ps were recorded in some preparations. The mean frequency of m.e.p.ps appeared to fall after several hours in the venom.5. The quantal content of endplate potentials (e.p.ps) was reduced by the venom. With low concentrations (1 mug/ml), an initial increase in quantal content was often seen. When the quantal content was markedly depressed there was no parallel reduction in the amplitude of nerve terminal spikes recorded extracellularly, though a later fall in size and slowing of time course was often seen.6. There was evidence that TSV eventually changed the normal Poisson characteristics of the spontaneous release of quanta and this may be correlated with electronmicroscopic changes in nerve terminals.7. Tiger snake antivenene counteracted the postsynaptic, but not the presynaptic effects of TSV when they had developed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367126"}
{"pmid": "4367127", "title": "Transformation of chick embryo neuroretinal cells by Rous sarcoma virus in vitro: induction of cell proliferation.", "content": "Transformation of chick embryo neuroretinal cells by Rous sarcoma virus in vitro: induction of cell proliferation. Neuroretinal cells from 7-day-old chick embryos are transformed and induced to proliferate after infection with Rous sarcoma virus in vitro. Susceptibility of neuroretinal cells to the virus is also dependent on the stage of development since infection of cells from 10-day-old embryos is uneffective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367127"}
{"pmid": "4367128", "title": "Management of burn syndactyly.", "content": "Management of burn syndactyly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367128"}
{"pmid": "4367130", "title": "Degranulation of sensitised rat peritoneal mast cells in response to antigen, compound 48-80 and polymyxin B. A scanning electron microscope study.", "content": "Degranulation of sensitised rat peritoneal mast cells in response to antigen, compound 48-80 and polymyxin B. A scanning electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367130"}
{"pmid": "4367132", "title": "The distribution of 5-bromodeoxyuridine in the DNA of polyoma-transformed mouse cells and some apparent effects on transcription.", "content": "The distribution of 5-bromodeoxyuridine in the DNA of polyoma-transformed mouse cells and some apparent effects on transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367132"}
{"pmid": "4367129", "title": "Studies on a murine form of spontaneous lower motor neuron degeneration--the wobbler (wa) mouse.", "content": "Studies on a murine form of spontaneous lower motor neuron degeneration--the wobbler (wa) mouse. The wobbler (wr) mouse has been considered an animal model of spontaneous lower motor neuron degeneration which is inherited as an autosomal recessive trait. Previously available data are, however, also compatible with genetic factors playing a necessary though not exclusive role in the expression of the wobbler trait. The present report describes the results of chromosome analyses, electromyography and selected histochemical studies on wobbler mice, as well as studies exploring the possible participation of infectious agents, transneuronal effects, retrograde effects, aging, circulating toxins and immunologic factors in the pathogenesis of the wobbler disorder. The data obtained do not implicate any of these mechanisms in the pathogenesis of the wobbler trait and also indicate that the wobbler mouse is not a clinical variant of the recently described type C oncornavirus-induced murine paralytic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367129"}
{"pmid": "4367131", "title": "Chemotactic responses of human polymorphonuclear leukocytes to cyclic GMP and other compounds.", "content": "Chemotactic responses of human polymorphonuclear leukocytes to cyclic GMP and other compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367131"}
{"pmid": "4367133", "title": "Infectious pericarditis in children.", "content": "Infectious pericarditis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367133"}
{"pmid": "4367134", "title": "Muscular hypertrophy in hypothyroid children: the Kocher-Debré-Semelaigne syndrome. A review of 23 cases.", "content": "Muscular hypertrophy in hypothyroid children: the Kocher-Debré-Semelaigne syndrome. A review of 23 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367134"}
{"pmid": "4367135", "title": "Postural protection against complications in radiculography with dimer X.", "content": "Postural protection against complications in radiculography with dimer X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367135"}
{"pmid": "4367136", "title": "Type-specific tumor patterns in the combined early and late cerebral scintigrams.", "content": "Type-specific tumor patterns in the combined early and late cerebral scintigrams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367136"}
{"pmid": "4367138", "title": "The binding of 1alpha-hydroxycorticosterone to tissue soluble proteins in the skate, Raja ocellata.", "content": "The binding of 1alpha-hydroxycorticosterone to tissue soluble proteins in the skate, Raja ocellata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367138"}
{"pmid": "4367137", "title": "Trophic functions of the neuron. VI. Other trophic systems. Taste bud regeneration in organ culture.", "content": "Trophic functions of the neuron. VI. Other trophic systems. Taste bud regeneration in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367137"}
{"pmid": "4367139", "title": "Studies on fish liver protein synthesis. I. Isolation and characterization of shark liver transfer ribonucleic acid.", "content": "Studies on fish liver protein synthesis. I. Isolation and characterization of shark liver transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367139"}
{"pmid": "4367141", "title": "Development of host-mediated mutagenicity tests. I. Differential response of yeast cells injected into testes of rats and peritoneum of mice and rats to mutagens.", "content": "Development of host-mediated mutagenicity tests. I. Differential response of yeast cells injected into testes of rats and peritoneum of mice and rats to mutagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367141"}
{"pmid": "4367140", "title": "Mutagenicity of hycanthone in Drosophila melanogaster.", "content": "Mutagenicity of hycanthone in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367140"}
{"pmid": "4367143", "title": "Assessment of biological age. Methodological study in two finnish populations.", "content": "Assessment of biological age. Methodological study in two finnish populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367143"}
{"pmid": "4367146", "title": "Monosynaptic projections from the pontine reticular formation to the 3rd nucleus in the cat.", "content": "Monosynaptic projections from the pontine reticular formation to the 3rd nucleus in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367146"}
{"pmid": "4367142", "title": "Observations on pathogenic organisms in the airborne state.", "content": "Observations on pathogenic organisms in the airborne state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367142"}
{"pmid": "4367145", "title": "Presynaptic modulation of la fiber synaptic effectiveness without concurrent postsynaptic inhibitory conductances.", "content": "Presynaptic modulation of la fiber synaptic effectiveness without concurrent postsynaptic inhibitory conductances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367145"}
{"pmid": "4367147", "title": "Ultrastructural aspects of the liver in cases of constitutional non haemolytic hyperbilirubinemia before and after treatment with barbiturates. Morphological aspects of enzymatic induction.", "content": "Ultrastructural aspects of the liver in cases of constitutional non haemolytic hyperbilirubinemia before and after treatment with barbiturates. Morphological aspects of enzymatic induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367147"}
{"pmid": "4367149", "title": "Canine glomeruli: light and electron microscopic change in biopsy, perfused, and in situ autolyzed kidney from normal dogs.", "content": "Canine glomeruli: light and electron microscopic change in biopsy, perfused, and in situ autolyzed kidney from normal dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367149"}
{"pmid": "4367151", "title": "A contribution to the study on embryonal lung cancer (alveogonioma).", "content": "A contribution to the study on embryonal lung cancer (alveogonioma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367151"}
{"pmid": "4367150", "title": "A review of prostaglandin F2alpha for ovulation control in cows and mares.", "content": "A review of prostaglandin F2alpha for ovulation control in cows and mares.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367150"}
{"pmid": "4367156", "title": "Persistence and expression of the herpes simplex virus type 2 genome in cervical tumor cells.", "content": "Persistence and expression of the herpes simplex virus type 2 genome in cervical tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367156"}
{"pmid": "4367157", "title": "Nasopharyngeal carcinoma: present status of knowledge.", "content": "Nasopharyngeal carcinoma: present status of knowledge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367157"}
{"pmid": "4367158", "title": "Transformation of nonhuman primate lymphocytes by Epstein-Barr virus.", "content": "Transformation of nonhuman primate lymphocytes by Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367158"}
{"pmid": "4367159", "title": "Uranyl acetate as an excellent fixative for lipoproteins after electrophoresis on agarose gel.", "content": "Uranyl acetate as an excellent fixative for lipoproteins after electrophoresis on agarose gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367159"}
{"pmid": "4367173", "title": "Formation of high-energy phosphate bonds effected by electron-deficient sulfides.", "content": "Formation of high-energy phosphate bonds effected by electron-deficient sulfides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367173"}
{"pmid": "4367171", "title": "Newer beta-lactam antibiotics.", "content": "Newer beta-lactam antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367171"}
{"pmid": "4367176", "title": "Meningeal and glial tumors in combination.", "content": "Meningeal and glial tumors in combination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367176"}
{"pmid": "4367172", "title": "Antineoplastic substances from the sea: a review.", "content": "Antineoplastic substances from the sea: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367172"}
{"pmid": "4367178", "title": "Cross-reacting tumor-associated antigen(s) of adenovirus type 9-induced fibroadenomas and a chemically induced mammary carcinoma in rats.", "content": "Cross-reacting tumor-associated antigen(s) of adenovirus type 9-induced fibroadenomas and a chemically induced mammary carcinoma in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367178"}
{"pmid": "4367179", "title": "Enhanced Na+-K+-activated adenosine triphosphatase activity in transformed fibroblasts.", "content": "Enhanced Na+-K+-activated adenosine triphosphatase activity in transformed fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367179"}
{"pmid": "4367174", "title": "Interrelation of afferent impluses from different bellies of the temporal muscle of the cat.", "content": "Interrelation of afferent impluses from different bellies of the temporal muscle of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367174"}
{"pmid": "4367181", "title": "The immunologic modulation of infectious disease pathogenesis. Friedenwald Lecture, 1973.", "content": "The immunologic modulation of infectious disease pathogenesis. Friedenwald Lecture, 1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367181"}
{"pmid": "4367180", "title": "Radioimmunoassay for mouse mammary tumor virus-associated antigen.", "content": "Radioimmunoassay for mouse mammary tumor virus-associated antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367180"}
{"pmid": "4367182", "title": "Klinefelter syndrome and cancer. A family study.", "content": "Klinefelter syndrome and cancer. A family study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367182"}
{"pmid": "4367175", "title": "Pathways for glucose metabolism in the rat gingiva. I. Patterns of enzymes of glucose metabolism.", "content": "Pathways for glucose metabolism in the rat gingiva. I. Patterns of enzymes of glucose metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367175"}
{"pmid": "4367186", "title": "Association of Wolff-Parkinson-White syndrome with congenital abnormalities of hands and feet.", "content": "Association of Wolff-Parkinson-White syndrome with congenital abnormalities of hands and feet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367186"}
{"pmid": "4367194", "title": "Electroneurography in intermittent claudication due to obliterative arteriosclerosis.", "content": "Electroneurography in intermittent claudication due to obliterative arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367194"}
{"pmid": "4367193", "title": "A sporadic case of apparent Crouzon's syndrome with extracraniofacial manifestations.", "content": "A sporadic case of apparent Crouzon's syndrome with extracraniofacial manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367193"}
{"pmid": "4367197", "title": "Association of PPi-phosphohydrolytic activity with fractions of alkaline orthophosphatase (EC 3.1.3.1) from human placenta.", "content": "Association of PPi-phosphohydrolytic activity with fractions of alkaline orthophosphatase (EC 3.1.3.1) from human placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367197"}
{"pmid": "4367200", "title": "Isolation of infectious bovine rhinotracheitis virus from feces of a feeder steer.", "content": "Isolation of infectious bovine rhinotracheitis virus from feces of a feeder steer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367200"}
{"pmid": "4367201", "title": "Epipolythiopiperazinedione antibiotics from Penicillium turbatum.", "content": "Epipolythiopiperazinedione antibiotics from Penicillium turbatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367201"}
{"pmid": "4367192", "title": "Suggestive evidence for an oncorna-virus-specific DNA polymerase from C-type particles of bovine leukosis.", "content": "Suggestive evidence for an oncorna-virus-specific DNA polymerase from C-type particles of bovine leukosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367192"}
{"pmid": "4367198", "title": "Influence of sodium and cyclic AMP on the passive permeability of the mucosal membrane in the rat intestine.", "content": "Influence of sodium and cyclic AMP on the passive permeability of the mucosal membrane in the rat intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367198"}
{"pmid": "4367199", "title": "The lysosomal enzymes in the regression of the mesonephron. Histochemical observations on chick embryo development.", "content": "The lysosomal enzymes in the regression of the mesonephron. Histochemical observations on chick embryo development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367199"}
{"pmid": "4367209", "title": "The resident's page: pathologic quiz case 2.", "content": "The resident's page: pathologic quiz case 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367209"}
{"pmid": "4367208", "title": "Adenoid cystic carcinoma in the head and neck (cylindroma).", "content": "Adenoid cystic carcinoma in the head and neck (cylindroma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367208"}
{"pmid": "4367210", "title": "Three dimensional structure of adenyl kinase.", "content": "Three dimensional structure of adenyl kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367210"}
{"pmid": "4367211", "title": "Comparison of predicted and experimentally determined secondary structure of adenyl kinase.", "content": "Comparison of predicted and experimentally determined secondary structure of adenyl kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367211"}
{"pmid": "4367212", "title": "Topological comparison of adenyl kinase with other proteins.", "content": "Topological comparison of adenyl kinase with other proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367212"}
{"pmid": "4367213", "title": "Food vacuole membrane in nutrient uptake by Tetrahymena.", "content": "Food vacuole membrane in nutrient uptake by Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367213"}
{"pmid": "4367214", "title": "The reaction of xanthine oxidase with molecular oxygen.", "content": "The reaction of xanthine oxidase with molecular oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367214"}
{"pmid": "4367215", "title": "The mechanism of action of xanthine oxidase.", "content": "The mechanism of action of xanthine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367215"}
{"pmid": "4367218", "title": "Heme-spin label studies of hemoglobin. I. Preparation and properties of heme-spin-labeled ferrihemoglobin.", "content": "Heme-spin label studies of hemoglobin. I. Preparation and properties of heme-spin-labeled ferrihemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367218"}
{"pmid": "4367217", "title": "Effects of temperature on conformation, hydroxylation, and secretion of chick tendon procollagen.", "content": "Effects of temperature on conformation, hydroxylation, and secretion of chick tendon procollagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367217"}
{"pmid": "4367216", "title": "Effect of sulfate on the activity and the kinetics of dexoyribonucleic acid degradation by porcine spleen deoxyribonuclease.", "content": "Effect of sulfate on the activity and the kinetics of dexoyribonucleic acid degradation by porcine spleen deoxyribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367216"}
{"pmid": "4367219", "title": "The mechanism of action of ethanolamine ammonia-lyase, a B-12-dependent enzyme. The participation of paramagnetic species in the catalytic deamination of 2-aminopropanol.", "content": "The mechanism of action of ethanolamine ammonia-lyase, a B-12-dependent enzyme. The participation of paramagnetic species in the catalytic deamination of 2-aminopropanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367219"}
{"pmid": "4367220", "title": "Interactions of saccharides with concanavalin A. Relation between calcium ions and the binding of saccharides to concanavalin A.", "content": "Interactions of saccharides with concanavalin A. Relation between calcium ions and the binding of saccharides to concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367220"}
{"pmid": "4367222", "title": "The recovery of anaerobic bacteria from swabs.", "content": "The recovery of anaerobic bacteria from swabs. When a standard sample of simulated exudate containing known numbers of anaerobic bacteria was taken up on a swab and plated on solid medium, the number of colonies subsequently cultured represented a very small proportion of the original sample. Evidence is produced that the apparent loss is not primarily attributable to inactivation on the swab but rather to retention of organisms on the swab. This was demonstrable with Clostridium welchii and with Bacteroides species that have hitherto been regarded as relatively oxygen-sensitive.When stock strains of Bacteroides species were held for some hours on swabs, some progressive loss of viability was demonstrable. A measure of protection was afforded when these organisms were held aerobically on blood agar medium, but a very exacting anaerobe and some wild strains of faecal anaerobes showed gradual inactivation under these conditions.These findings may have important implications in relation to currently employed bacteriological sampling procedures with swabs in clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367222"}
{"pmid": "4367221", "title": "Selective binding of human interferon to albumin immoblized on agarose.", "content": "Selective binding of human interferon to albumin immoblized on agarose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367221"}
{"pmid": "4367223", "title": "A study of foot-and-mouth disease virus strains by complement fixation. I. A model for the fixation of complement by antigen-antibody mixtures.", "content": "A study of foot-and-mouth disease virus strains by complement fixation. I. A model for the fixation of complement by antigen-antibody mixtures. An examination was made of the relations between antigen, antibody and fixation of complement with foot-and-mouth disease virus (FMDV). It was found that complement fixation in this system follows the same principles as models developed in other antigen/antibody systems. The assumption that there is a relation of direct proportionality between the amount of complement fixed and the amount of antiserum reacting with constant antigen was found to be incorrect. An alternative method was proposed for the quantitative differentiation of FMDV strains by comparing the titres of an antiserum when reacting with optimum amounts of homologous or heterologous antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367223"}
{"pmid": "4367224", "title": "A study of foot-and-mouth disease virus strains by complement fixation. II. A comparison of tube and microplate tests for the differentiation of strains.", "content": "A study of foot-and-mouth disease virus strains by complement fixation. II. A comparison of tube and microplate tests for the differentiation of strains. Several foot-and-mouth disease virus strains were examined by complement-fixation tests in microplates and in tubes. It was established that the two systems are comparable, although greater reproducibility is obtained with tube tests. While microplate tests are a satisfactory method for the differentiation of strains, tube tests provide a more precise method for the identification of small antigenic differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367224"}
{"pmid": "4367225", "title": "Viruses associated with acute respiratory infections 1961-71.", "content": "Viruses associated with acute respiratory infections 1961-71. Influenza-like illness, cold and sore throat was the diagnosis given in over 80% of 5177 acute respiratory illnesses in patients swabbed over a 10-year-period. A pathogenic organism was isolated twice as frequently from patients with a sore throat or an influenza-like illness as from those diagnosed as suffering from croup or laryngitis and bronchitis. A laboratory diagnosis was commoner in school children than in older or younger persons.Most of the organisms isolated were found in association with all types of acute respiratory illness but, with increasing age of the patient, one particular agent or group of agents was more likely to be of aetiological significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367225"}
{"pmid": "4367227", "title": "Diagnosis of idiopathic hypertrophic subaortic stenosis by right ventricular septal biopsy.", "content": "Diagnosis of idiopathic hypertrophic subaortic stenosis by right ventricular septal biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367227"}
{"pmid": "4367226", "title": "Antibodies against adeno-, cytomegalo and rubella viruses in Australia-antigen-negative sera from patients with infectious hepatitis.", "content": "Antibodies against adeno-, cytomegalo and rubella viruses in Australia-antigen-negative sera from patients with infectious hepatitis. Antibodies neutralizing adenovirus type 5 were found in all of 50 pairs (100%) of sera from patients with acute icteric infectious hepatitis. The incidence in sera from the general population was 57%. No differences in mean titre or in proportion of positive sera were found in the same sera tested for complement-fixing antibodies to cytomegalovirus and for antibodies to rubella virus haemagglutinin. The results can be interpreted as supporting the involvement, either direct or indirect, of adenovirus in the aetiology of infectious hepatitis; but could also be due to a non-specific anamnestic enhancement of the production of antibody to adenovirus, or to coincidental infection with adenovirus and the agent of infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367226"}
{"pmid": "4367229", "title": "The Brenner tumor and the Walthard cell nest. An electron microscopic study.", "content": "The Brenner tumor and the Walthard cell nest. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367229"}
{"pmid": "4367228", "title": "The Golgi complex. II. The effects of aminonucleoside on ultrastructure and glycoprotein biosynthesis.", "content": "The Golgi complex. II. The effects of aminonucleoside on ultrastructure and glycoprotein biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367228"}
{"pmid": "4367230", "title": "Ultrastructure of the parafollicular (C) cells and the parathyroid cell in growing dogs on a high calcium diet.", "content": "Ultrastructure of the parafollicular (C) cells and the parathyroid cell in growing dogs on a high calcium diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367230"}
{"pmid": "4367232", "title": "Evaluation of a new mucolytic drug.", "content": "Evaluation of a new mucolytic drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367232"}
{"pmid": "4367231", "title": "Pharmacologic effects of nicotinic acid on human purine metabolism.", "content": "Pharmacologic effects of nicotinic acid on human purine metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367231"}
{"pmid": "4367234", "title": "Spontaneous eyelid behavior in the sleeping cat.", "content": "Spontaneous eyelid behavior in the sleeping cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367234"}
{"pmid": "4367235", "title": "Effects of glutamate on spontaneous electrical activity in the embryonic chick cerebrum.", "content": "Effects of glutamate on spontaneous electrical activity in the embryonic chick cerebrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367235"}
{"pmid": "4367236", "title": "Rigidity and primary motoneuron damage in tetanus.", "content": "Rigidity and primary motoneuron damage in tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367236"}
{"pmid": "4367237", "title": "The uptake process for gamma-aminobutyric acid in cultures of developing chick cerebrum.", "content": "The uptake process for gamma-aminobutyric acid in cultures of developing chick cerebrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367237"}
{"pmid": "4367238", "title": "Superinfection with adenovirus of Burkitt's lymphoma cell lines.", "content": "Superinfection with adenovirus of Burkitt's lymphoma cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367238"}
{"pmid": "4367240", "title": "Effects of partial hepatectomy on carcinogenicity, metabolism, and binding to DNA of ethyl carbamate.", "content": "Effects of partial hepatectomy on carcinogenicity, metabolism, and binding to DNA of ethyl carbamate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367240"}
{"pmid": "4367239", "title": "Isolation and characterization of a cell line from the cocultivation of Lucké renal tumor cells and nontransformed feeder cells.", "content": "Isolation and characterization of a cell line from the cocultivation of Lucké renal tumor cells and nontransformed feeder cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367239"}
{"pmid": "4367241", "title": "Cell culture from a rat brain tumor induced by intracerebral inoculation with murine sarcoma virus.", "content": "Cell culture from a rat brain tumor induced by intracerebral inoculation with murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367241"}
{"pmid": "4367242", "title": "Effect of cyclopropenoid compounds on the carcinogenic activity of diethylnitrosamine and aflatoxin B1 in rats.", "content": "Effect of cyclopropenoid compounds on the carcinogenic activity of diethylnitrosamine and aflatoxin B1 in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367242"}
{"pmid": "4367243", "title": "Neuraminidase and cell viability: failure to detect cytotoxic effects with dye-exclusion techniques.", "content": "Neuraminidase and cell viability: failure to detect cytotoxic effects with dye-exclusion techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367243"}
{"pmid": "4367244", "title": "In vivo inhibition of murine leukemia and sarcoma viruses by the heteropolyanion 5-tungsto-2-antimoniate.", "content": "In vivo inhibition of murine leukemia and sarcoma viruses by the heteropolyanion 5-tungsto-2-antimoniate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367244"}
{"pmid": "4367245", "title": "Suppression of chemically induced pulmonary tumors by treatment of strain A mice with murine sarcoma virus.", "content": "Suppression of chemically induced pulmonary tumors by treatment of strain A mice with murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367245"}
{"pmid": "4367247", "title": "Ultrastructural studies of cell-virus interaction in reptilian cell lines. II. Distribution, incidence, and factors enhancing the production of intramitochondrial virions.", "content": "Ultrastructural studies of cell-virus interaction in reptilian cell lines. II. Distribution, incidence, and factors enhancing the production of intramitochondrial virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367247"}
{"pmid": "4367248", "title": "Destruction of syngeneic tumors by tuberculin-stimulated peritoneal exudate cells from guinea pigs immunized to Mycobacterium bovis (strain BCG).", "content": "Destruction of syngeneic tumors by tuberculin-stimulated peritoneal exudate cells from guinea pigs immunized to Mycobacterium bovis (strain BCG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367248"}
{"pmid": "4367246", "title": "The murine male antigen. 3. Variable expression of H-Y by murine tumors.", "content": "The murine male antigen. 3. Variable expression of H-Y by murine tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367246"}
{"pmid": "4367249", "title": "Induction of adenofibrosis and hepatomas of the liver in BALB-cJ mice by polychlorinated biphenyls (Aroclor 1254).", "content": "Induction of adenofibrosis and hepatomas of the liver in BALB-cJ mice by polychlorinated biphenyls (Aroclor 1254).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367249"}
{"pmid": "4367250", "title": "Several changes associated with the acquisition of a single chromosome in rat glial tumor cells.", "content": "Several changes associated with the acquisition of a single chromosome in rat glial tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367250"}
{"pmid": "4367251", "title": "Treatment of metastatic Wilm's tumor.", "content": "Treatment of metastatic Wilm's tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367251"}
{"pmid": "4367252", "title": "Editorial: The \"oat-cell\" tumors: a medical and biological challenge.", "content": "Editorial: The \"oat-cell\" tumors: a medical and biological challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367252"}
{"pmid": "4367253", "title": "Drug levels in the target tissue and effect.", "content": "Drug levels in the target tissue and effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367253"}
{"pmid": "4367255", "title": "The supine subcostal modification of the thoraco-abdominal incision.", "content": "The supine subcostal modification of the thoraco-abdominal incision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367255"}
{"pmid": "4367254", "title": "Blood level measurements and antimicrobial agents.", "content": "Blood level measurements and antimicrobial agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367254"}
{"pmid": "4367257", "title": "Zinc deficiency and decreased pancreatic secretory response.", "content": "Zinc deficiency and decreased pancreatic secretory response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367257"}
{"pmid": "4367256", "title": "Peritubular membrane transport of PAH into proximal cells in Necturus kidney slices.", "content": "Peritubular membrane transport of PAH into proximal cells in Necturus kidney slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367256"}
{"pmid": "4367258", "title": "Comparison of the effects of cholera enterotoxin and ACTH on adrenal cells in tissue culture.", "content": "Comparison of the effects of cholera enterotoxin and ACTH on adrenal cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367258"}
{"pmid": "4367259", "title": "Pulmonary adema and hemorrhage as a consequence of systemic vasoconstriction.", "content": "Pulmonary adema and hemorrhage as a consequence of systemic vasoconstriction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367259"}
{"pmid": "4367260", "title": "Effect of pH on epinephrine-induced lipolysis in isolated fat cells.", "content": "Effect of pH on epinephrine-induced lipolysis in isolated fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367260"}
{"pmid": "4367261", "title": "Influence of sodium, potassium, and pituitary hormones on iso-renin in rat adrenal glands.", "content": "Influence of sodium, potassium, and pituitary hormones on iso-renin in rat adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367261"}
{"pmid": "4367262", "title": "Computer-assisted analysis of chromosomal abnormalities: detection of a deletion in aniridia-Wilms' tumor syndrome.", "content": "Computer-assisted analysis of chromosomal abnormalities: detection of a deletion in aniridia-Wilms' tumor syndrome. A chromosome translocation, t(8p + ; 11q -), in a patient with aniridia and Wilms' tumor, appeared balanced by standard techniques, including trypsin banding. Computer analysis of optical microscope scanning profiles of chromosome pairs 8 and 11 revealed an interstitial deletion of the short arm of 8. Computer analysis coupled to the new banding techniques provides greater resolution for the detection of subtle chromosomal variations not recognized by banding methods alone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367262"}
{"pmid": "4367264", "title": "Cancer of the pancreas induced in the Syrian golden hamster.", "content": "Cancer of the pancreas induced in the Syrian golden hamster. A high incidence of pancreatic neoplasms was induced in Syrian golden hamsters following subcutaneous applications of diisopropanolnitrosamine (DIPN) once weekly for life. The tumor latency was as short as 15 weeks. In clinical and morphologic aspects the induced pancreatic tumors closely resembled those of humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367264"}
{"pmid": "4367263", "title": "Toxic polyneuropathy produced by methyl N-butyl ketone.", "content": "Toxic polyneuropathy produced by methyl N-butyl ketone. A polyneuropathy affecting a large number of workers was recently observed at a plant producing plastic-coated and color-printed fabrics. Epidemiological data suggested strongly that methyl N-butyl ketone (MBK) was responsible for the outbreak. This hypothesis is now supported by the development of a peripheral neuropathy in chickens, rats, and cats exposed to MBK at atmospheric concentrations of 200 to 600 parts per million, 24 hours per day, 7 days per week. Although the animals were exposed continuously and the affected workers were exposed intermittently, the averages of the total number of hours of exposure for development of the peripheral neutropathy in the animals and workers were remarkably close.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367263"}
{"pmid": "4367265", "title": "Animal model of human disease. Burkitt's lymphoma, malignant lymphoma and lymphocytic leukemia.", "content": "Animal model of human disease. Burkitt's lymphoma, malignant lymphoma and lymphocytic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367265"}
{"pmid": "4367267", "title": "Altering lipid patterns in adult males.", "content": "Altering lipid patterns in adult males.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367267"}
{"pmid": "4367269", "title": "Reduced calcium absorption after nephrectomy in uremic patients.", "content": "Reduced calcium absorption after nephrectomy in uremic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367269"}
{"pmid": "4367268", "title": "The renin-angiotensin system (second of two parts).", "content": "The renin-angiotensin system (second of two parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367268"}
{"pmid": "4367270", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 34-1974.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 34-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367270"}
{"pmid": "4367271", "title": "Cellular pathology and uterine cancer. Ward Burdick Award address.", "content": "Cellular pathology and uterine cancer. Ward Burdick Award address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367271"}
{"pmid": "4367273", "title": "Effects of actinomycin D on RNA metabolism in the growing hair follicles of the mouse.", "content": "Effects of actinomycin D on RNA metabolism in the growing hair follicles of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367273"}
{"pmid": "4367272", "title": "Autoimmunity and neoplasia. The possible role of C-type viruses.", "content": "Autoimmunity and neoplasia. The possible role of C-type viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367272"}
{"pmid": "4367274", "title": "Carcinoma of the gallbladder and extrahepatic biliary tree.", "content": "Carcinoma of the gallbladder and extrahepatic biliary tree.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367274"}
{"pmid": "4367276", "title": "Macrodactyly and localized hypertrophic neuropathy.", "content": "Macrodactyly and localized hypertrophic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367276"}
{"pmid": "4367277", "title": "The innervation of muscle spindles in a case of hypertrophic polyneuropathy.", "content": "The innervation of muscle spindles in a case of hypertrophic polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367277"}
{"pmid": "4367275", "title": "Ocular myasthenia gravis mimicking progressive external ophthalmoplegia. Rare case of myasthenia associated with peripheral neuropathy and spastic paraparesis.", "content": "Ocular myasthenia gravis mimicking progressive external ophthalmoplegia. Rare case of myasthenia associated with peripheral neuropathy and spastic paraparesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367275"}
{"pmid": "4367278", "title": "The fate of kidney transplants from donors with minor renal abnormalities.", "content": "The fate of kidney transplants from donors with minor renal abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367278"}
{"pmid": "4367279", "title": "Trace elements in noraml and malignant human breast tissue.", "content": "Trace elements in noraml and malignant human breast tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367279"}
{"pmid": "4367281", "title": "Letter: Effect of exogenous oestrogens on minor psychiatric symptoms in postmenopausal women.", "content": "Letter: Effect of exogenous oestrogens on minor psychiatric symptoms in postmenopausal women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367281"}
{"pmid": "4367282", "title": "Prevention of food poisoning in hospital patients.", "content": "Prevention of food poisoning in hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367282"}
{"pmid": "4367280", "title": "Oestrogen assays in gynaecology.", "content": "Oestrogen assays in gynaecology. The applications of total urinary estrogen and pregnanediol assays in nonpregnant patients are presented.  Estrogen levels provide information on overall ovarian activity, and when measured periodically during the ovulatory cycle, give values of 10-20 mcg/24 hours during the first week, 45-100 mcg/24 hours just before ovulation, then back down and  up again to a second maximum of 30-100 mcg/24 hours during the luteal phase.  Urinary estrogen levels are useful in determining whether ovarian function is present or absent, since values remain less than 10 mcg/24 hours in complete absence of ovarian activity.  Anovulatory cycles are also characterized by low pregnanediol levels.  These assays are also important in determining proper dosage for gonadotrophin and clomiphene treatment.  Both assays are useful in the differentiation between disease and normal pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367280"}
{"pmid": "4367284", "title": "The preparation of microsomal fractions of rodent respiratory tract and their characterization.", "content": "The preparation of microsomal fractions of rodent respiratory tract and their characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367284"}
{"pmid": "4367283", "title": "Enhancement of 7,12-dimethylbenzanthracene skin carcinogenesis by adenosine 3',5'-cyclic monophosphate.", "content": "Enhancement of 7,12-dimethylbenzanthracene skin carcinogenesis by adenosine 3',5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367283"}
{"pmid": "4367285", "title": "A comparative study of rat liver, muscle, and hepatoma 3924A phosphofructokinase isozymes.", "content": "A comparative study of rat liver, muscle, and hepatoma 3924A phosphofructokinase isozymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367285"}
{"pmid": "4367287", "title": "Synthesis, toxicities, and carcinogenicities of carcinogenic bifunctional aminoazo dyes.", "content": "Synthesis, toxicities, and carcinogenicities of carcinogenic bifunctional aminoazo dyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367287"}
{"pmid": "4367286", "title": "Endogenous type C particles from rat embryo cells treated with 5-bromodeoxyuridine.", "content": "Endogenous type C particles from rat embryo cells treated with 5-bromodeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367286"}
{"pmid": "4367288", "title": "Isozyme patterns of pyruvate kinase in various primary liver tumors induced during the process of hepatocarcinogenesis.", "content": "Isozyme patterns of pyruvate kinase in various primary liver tumors induced during the process of hepatocarcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367288"}
{"pmid": "4367290", "title": "Rabbit antibodies to nucleoli of Novikoff hepatoma and normal liver of the rat.", "content": "Rabbit antibodies to nucleoli of Novikoff hepatoma and normal liver of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367290"}
{"pmid": "4367289", "title": "Substrate requirements and kinetic analysis of the cortisol effects on uridine uptake and incorporation by mouse lymphoma P1798 cells in vitro.", "content": "Substrate requirements and kinetic analysis of the cortisol effects on uridine uptake and incorporation by mouse lymphoma P1798 cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367289"}
{"pmid": "4367291", "title": "Polyamine depletion of tumor tissue and subsequent elevation of spermidine in the sera of rats with 3924A hepatomas after 5-fluorouracil administration.", "content": "Polyamine depletion of tumor tissue and subsequent elevation of spermidine in the sera of rats with 3924A hepatomas after 5-fluorouracil administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367291"}
{"pmid": "4367292", "title": "Stromal nephromas and renal cell tumors in suckling and weaned rats.", "content": "Stromal nephromas and renal cell tumors in suckling and weaned rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367292"}
{"pmid": "4367293", "title": "Transfer RNA methylase activity in benign human ovarian neoplasms.", "content": "Transfer RNA methylase activity in benign human ovarian neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367293"}
{"pmid": "4367295", "title": "Overview on pathogenesis of cardiac hypertrophy.", "content": "Overview on pathogenesis of cardiac hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367295"}
{"pmid": "4367297", "title": "Massive hemothorax: two unusual cases.", "content": "Massive hemothorax: two unusual cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367297"}
{"pmid": "4367299", "title": "Travelers' warning: dipyrone in over-the-counter drugs.", "content": "Travelers' warning: dipyrone in over-the-counter drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367299"}
{"pmid": "4367298", "title": "Bilateral symmetrical metastases to the clavicular heads from bronchogenic carcinoma simulating primary hyperparathyroidism.", "content": "Bilateral symmetrical metastases to the clavicular heads from bronchogenic carcinoma simulating primary hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367298"}
{"pmid": "4367300", "title": "Proceedings: Electron spin resonance study of the role of calcium in the fibrinogen fibrin reaction.", "content": "Proceedings: Electron spin resonance study of the role of calcium in the fibrinogen fibrin reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367300"}
{"pmid": "4367301", "title": "The role of transferrin in iron transport.", "content": "The role of transferrin in iron transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367301"}
{"pmid": "4367302", "title": "A temperature-sensitive mutant of herpes simplex virus type 1 defective in the synthesis of the major capsid polypeptide.", "content": "A temperature-sensitive mutant of herpes simplex virus type 1 defective in the synthesis of the major capsid polypeptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367302"}
{"pmid": "4367303", "title": "Inhibition of foot-and-mouth disease virus replicase by frog virus 3 particles.", "content": "Inhibition of foot-and-mouth disease virus replicase by frog virus 3 particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367303"}
{"pmid": "4367304", "title": "The induction of deoxythymidine kinase by bacteriophage T4.", "content": "The induction of deoxythymidine kinase by bacteriophage T4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367304"}
{"pmid": "4367305", "title": "Electron microscopic observations on the entry of influenza virus into susceptible cells.", "content": "Electron microscopic observations on the entry of influenza virus into susceptible cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367305"}
{"pmid": "4367306", "title": "Transformation of rat embryo cells by temperature-sensitive mutants of herpes simplex virus.", "content": "Transformation of rat embryo cells by temperature-sensitive mutants of herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367306"}
{"pmid": "4367307", "title": "Inactivation of some bacterial and animal viruses by exposure to liquid-air interfaces.", "content": "Inactivation of some bacterial and animal viruses by exposure to liquid-air interfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367307"}
{"pmid": "4367308", "title": "The IgG receptor induced by herpes simplex virus: studies using radioiodinated IgG.", "content": "The IgG receptor induced by herpes simplex virus: studies using radioiodinated IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367308"}
{"pmid": "4367309", "title": "Absence of a requirement for host polypeptides in the herpes virus thymidine kinase.", "content": "Absence of a requirement for host polypeptides in the herpes virus thymidine kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367309"}
{"pmid": "4367311", "title": "Treatment of gestational trophoblastic disease.", "content": "Treatment of gestational trophoblastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367311"}
{"pmid": "4367310", "title": "A clinical test useful for predicting the development of acute hypertension in pregnancy.", "content": "A clinical test useful for predicting the development of acute hypertension in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367310"}
{"pmid": "4367312", "title": "Relative importance of viral and neoantigens in cytotoxic reaction against murine leukaemia cells.", "content": "Relative importance of viral and neoantigens in cytotoxic reaction against murine leukaemia cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367312"}
{"pmid": "4367313", "title": "Simple siliceous pneumoconiosis in Negev Bedouins.", "content": "Simple siliceous pneumoconiosis in Negev Bedouins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367313"}
{"pmid": "4367315", "title": "The inhibition of mouse bone collagenase by lysozyme.", "content": "The inhibition of mouse bone collagenase by lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367315"}
{"pmid": "4367316", "title": "Vibrational spectra of some phosphate salts amorphous to X-ray diffraction.", "content": "Vibrational spectra of some phosphate salts amorphous to X-ray diffraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367316"}
{"pmid": "4367314", "title": "The lipids of matrix vesicles from bovine fetal epiphyseal cartilage.", "content": "The lipids of matrix vesicles from bovine fetal epiphyseal cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367314"}
{"pmid": "4367317", "title": "The effect of galactose on bone metabolism.", "content": "The effect of galactose on bone metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367317"}
{"pmid": "4367318", "title": "Vitamin A deficiency stimulated phosphatase activity in epiphyseal chick cartilage.", "content": "Vitamin A deficiency stimulated phosphatase activity in epiphyseal chick cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367318"}
{"pmid": "4367321", "title": "Cytochemical, ultrastructural, and autoradiographic study of the intranuclear crystals in the midgut cells of Gyrinus marinus Gyll.", "content": "Cytochemical, ultrastructural, and autoradiographic study of the intranuclear crystals in the midgut cells of Gyrinus marinus Gyll.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367321"}
{"pmid": "4367319", "title": "Human serum albumin phenotype activation in mouse hepatoma--human leukocyte cell hybrids.", "content": "Human serum albumin phenotype activation in mouse hepatoma--human leukocyte cell hybrids. Murine hepatoma cells that secreted mouse serum albumin were fused with human leukocytes that did not produce albumin. The resulting hybrids secreted both mouse and human serum albumin, as demonstrated by immuno-electrophoretic techniques. The activation of the human genome suggests that mapping genes governing specialized functions in somatic cell hybrids may be accomplished by using adifferentiated human cells as a parental line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367319"}
{"pmid": "4367320", "title": "Antibody to leukemia virus: widespread occurrence in inbred mice.", "content": "Antibody to leukemia virus: widespread occurrence in inbred mice. Mice from a wide variety of inbred strains produce immunoglobulin G antibody against murine leukemia virus. This is contrary to the common view that the mouse is immunologically tolerant to its endogenous leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367320"}
{"pmid": "4367323", "title": "Cooperative effects of AMP, ATP and fructose 1,6-P2 on the specific elution of fructose 1,6-diphosphatase from cellulose phosphate.", "content": "Cooperative effects of AMP, ATP and fructose 1,6-P2 on the specific elution of fructose 1,6-diphosphatase from cellulose phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367323"}
{"pmid": "4367322", "title": "Affinity chromatography. New approaches for the preparation of spacer containing derivatives and for specific isolation of peptides.", "content": "Affinity chromatography. New approaches for the preparation of spacer containing derivatives and for specific isolation of peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367322"}
{"pmid": "4367324", "title": "The biosynthesis of riboflavin: affinity chromatography purification of GTP-ring-opening enzyme.", "content": "The biosynthesis of riboflavin: affinity chromatography purification of GTP-ring-opening enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367324"}
{"pmid": "4367325", "title": "Immobilized polynucleotides and nucleic acids.", "content": "Immobilized polynucleotides and nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367325"}
{"pmid": "4367327", "title": "Preparation, characterization and applications of enzymes immobilized on inorganic supports.", "content": "Preparation, characterization and applications of enzymes immobilized on inorganic supports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367327"}
{"pmid": "4367326", "title": "Immobilized cofactors and multi-step enzyme-systems.", "content": "Immobilized cofactors and multi-step enzyme-systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367326"}
{"pmid": "4367329", "title": "The preparation of microenvironments for bound enzymes by solid phase peptide synthesis.", "content": "The preparation of microenvironments for bound enzymes by solid phase peptide synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367329"}
{"pmid": "4367328", "title": "The optimization of porous materials for immobilized enzyme (IME) systems.", "content": "The optimization of porous materials for immobilized enzyme (IME) systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367328"}
{"pmid": "4367330", "title": "Chain refolding and subunit interactions in enzyme molecules covalently bound to a solid matrix.", "content": "Chain refolding and subunit interactions in enzyme molecules covalently bound to a solid matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367330"}
{"pmid": "4367331", "title": "Use of immobilized enzymes for synthetic purposes.", "content": "Use of immobilized enzymes for synthetic purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367331"}
{"pmid": "4367332", "title": "Studies on the site of origin of the androgen binding protein present in epididymal cytosol from mature intact rabbits.", "content": "Studies on the site of origin of the androgen binding protein present in epididymal cytosol from mature intact rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367332"}
{"pmid": "4367333", "title": "Androgen binding protein (ABP) in rabbit testis and epididymis.", "content": "Androgen binding protein (ABP) in rabbit testis and epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367333"}
{"pmid": "4367339", "title": "In vitro cellular immunity to Epstein-Barr virus in normal human subjects.", "content": "In vitro cellular immunity to Epstein-Barr virus in normal human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367339"}
{"pmid": "4367338", "title": "Disappearance of a major cell-type specific surface glycoprotein antigen (SF) after transformation of fibroblasts by Rous sarcoma virus.", "content": "Disappearance of a major cell-type specific surface glycoprotein antigen (SF) after transformation of fibroblasts by Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367338"}
{"pmid": "4367340", "title": "Attempts to detect virus-secific DNA in human tumors. I. Nucleic acid hybridizations with complementary RNA of human wart virus.", "content": "Attempts to detect virus-secific DNA in human tumors. I. Nucleic acid hybridizations with complementary RNA of human wart virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367340"}
{"pmid": "4367342", "title": "An analysis of variables affecting the measurement of tumor immunity in vitro with 125I-iododeoxyuridine-labelled target cells. Studies of immunity to primary Moloney sarcomas.", "content": "An analysis of variables affecting the measurement of tumor immunity in vitro with 125I-iododeoxyuridine-labelled target cells. Studies of immunity to primary Moloney sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367342"}
{"pmid": "4367341", "title": "Attempts to detect virus-specific DNA in human tumors. II. Nucleic acid hybridizations with complementary RNA of human herpes group viruses.", "content": "Attempts to detect virus-specific DNA in human tumors. II. Nucleic acid hybridizations with complementary RNA of human herpes group viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367341"}
{"pmid": "4367344", "title": "Proceedings: Influence of large doses of rifampicin on mammalian embryonic development.", "content": "Proceedings: Influence of large doses of rifampicin on mammalian embryonic development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367344"}
{"pmid": "4367343", "title": "Cell-mediated and humoral immunity studies of murine and hamster sarcoma virus-induced producer and non-producer tumors in syngeneic animals.", "content": "Cell-mediated and humoral immunity studies of murine and hamster sarcoma virus-induced producer and non-producer tumors in syngeneic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367343"}
{"pmid": "4367345", "title": "Proceedings: The effect of PGE1, PGE2 and PGF2alpha on parasympathetic transmission.", "content": "Proceedings: The effect of PGE1, PGE2 and PGF2alpha on parasympathetic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367345"}
{"pmid": "4367346", "title": "Proceedings: Calcium-dependent changes of adenylate cyclase activity by adenosine.", "content": "Proceedings: Calcium-dependent changes of adenylate cyclase activity by adenosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367346"}
{"pmid": "4367347", "title": "Proceedings: Effects of cyclic nucleotide monophosphates (cAMP, dbcAMP, cGMP, cIMP) on transepithelial netfluxes in proximal convolutions of rat kidneys.", "content": "Proceedings: Effects of cyclic nucleotide monophosphates (cAMP, dbcAMP, cGMP, cIMP) on transepithelial netfluxes in proximal convolutions of rat kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367347"}
{"pmid": "4367348", "title": "Proceedings: Iso-renin in adrenal glands of rats: a possible factor in steroid production.", "content": "Proceedings: Iso-renin in adrenal glands of rats: a possible factor in steroid production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367348"}
{"pmid": "4367350", "title": "Proceedings: The specificity of membranes of chromaffin granules: a biochemical and immunohistological study.", "content": "Proceedings: The specificity of membranes of chromaffin granules: a biochemical and immunohistological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367350"}
{"pmid": "4367349", "title": "Proceedings: Angiotensin receptors in the adrenal cortex.", "content": "Proceedings: Angiotensin receptors in the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367349"}
{"pmid": "4367351", "title": "Proceedings: The action of tetanus toxin on the electrical activity of the rabbit's brain.", "content": "Proceedings: The action of tetanus toxin on the electrical activity of the rabbit's brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367351"}
{"pmid": "4367353", "title": "Proceedings: Influence of hydroxyphenyl-orciprenalin (HO) on the cAMP level and the motility of the rat uterus in vitro.", "content": "Proceedings: Influence of hydroxyphenyl-orciprenalin (HO) on the cAMP level and the motility of the rat uterus in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367353"}
{"pmid": "4367352", "title": "Proceedings: (14C)-labelling and fractionation of lipids in bovine glomerular basement membrane.", "content": "Proceedings: (14C)-labelling and fractionation of lipids in bovine glomerular basement membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367352"}
{"pmid": "4367354", "title": "Proceedings: Cardiac effects of dibutyryl-C-AMP in several mammalian species.", "content": "Proceedings: Cardiac effects of dibutyryl-C-AMP in several mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367354"}
{"pmid": "4367355", "title": "Proceedings: Investigation of the antilipolytic action of clomiphene.", "content": "Proceedings: Investigation of the antilipolytic action of clomiphene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367355"}
{"pmid": "4367356", "title": "Proceedings: Effect of nicotine and nicotine monomethiodide on vascular adrenergic neuroeffector transmission.", "content": "Proceedings: Effect of nicotine and nicotine monomethiodide on vascular adrenergic neuroeffector transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367356"}
{"pmid": "4367358", "title": "Proceedings: Demonstration of the in vivo action of pepstatin: effects on plasma angiotensin II concentration (PAC).", "content": "Proceedings: Demonstration of the in vivo action of pepstatin: effects on plasma angiotensin II concentration (PAC).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367358"}
{"pmid": "4367359", "title": "Proceedings: Effects of antiphlogistic drugs on the adenyl cyclase system of fibroblasts.", "content": "Proceedings: Effects of antiphlogistic drugs on the adenyl cyclase system of fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367359"}
{"pmid": "4367357", "title": "Proceedings: Studies on the inhibitory effect of pepstatin on the renin--angiotensinogen reaction.", "content": "Proceedings: Studies on the inhibitory effect of pepstatin on the renin--angiotensinogen reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367357"}
{"pmid": "4367361", "title": "Proceedings: Effect of cholinergic mechanisms on rat gastric mucosal cAMP.", "content": "Proceedings: Effect of cholinergic mechanisms on rat gastric mucosal cAMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367361"}
{"pmid": "4367360", "title": "Proceedings: Synthesis of cyclic AMP and cyclic AMP-mediated protein phosphorylation in rat erythrocytes.", "content": "Proceedings: Synthesis of cyclic AMP and cyclic AMP-mediated protein phosphorylation in rat erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367360"}
{"pmid": "4367362", "title": "Proceedings: The ciliary ganglion of the cat: pharmacological aspects.", "content": "Proceedings: The ciliary ganglion of the cat: pharmacological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367362"}
{"pmid": "4367363", "title": "Proceedings: Effect of tropolone on vascular sympathetic neuroeffector transmission.", "content": "Proceedings: Effect of tropolone on vascular sympathetic neuroeffector transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367363"}
{"pmid": "4367364", "title": "Proceedings: The effect of norepinephrine on cyclic nucleotide concentrations in rat ductus deferens.", "content": "Proceedings: The effect of norepinephrine on cyclic nucleotide concentrations in rat ductus deferens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367364"}
{"pmid": "4367366", "title": "Proceedings: Effect of the alpha-receptor blocking agent phentolamine on cAMP levels and release of glycerol in isolated rat fat cells.", "content": "Proceedings: Effect of the alpha-receptor blocking agent phentolamine on cAMP levels and release of glycerol in isolated rat fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367366"}
{"pmid": "4367365", "title": "Proceedings: Adenosine 3',5'-monophosphate in cerebral cortical slices from guinea pig and rat: effect of benzodiazepines.", "content": "Proceedings: Adenosine 3',5'-monophosphate in cerebral cortical slices from guinea pig and rat: effect of benzodiazepines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367365"}
{"pmid": "4367368", "title": "The evaluation of the experience of various European countries in cancer control.", "content": "The evaluation of the experience of various European countries in cancer control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367368"}
{"pmid": "4367371", "title": "A fine structural study of human oral epithelium separated from the lamina propria by enzymatic action.", "content": "A fine structural study of human oral epithelium separated from the lamina propria by enzymatic action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367371"}
{"pmid": "4367372", "title": "A cytoplasmic inclusion in mouse trigeminal neurons (1).", "content": "A cytoplasmic inclusion in mouse trigeminal neurons (1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367372"}
{"pmid": "4367373", "title": "Primary breast cancer: some considerations concerning its management.", "content": "Primary breast cancer: some considerations concerning its management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367373"}
{"pmid": "4367375", "title": "Effect of histone on oncogenic properties of Moloney's murine sarcoma virus.", "content": "Effect of histone on oncogenic properties of Moloney's murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367375"}
{"pmid": "4367376", "title": "Specificity of rabbit IgM and IgG antibody in intratypic differentiation of poliovirus type I strains.", "content": "Specificity of rabbit IgM and IgG antibody in intratypic differentiation of poliovirus type I strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367376"}
{"pmid": "4367377", "title": "Herpesvirus strigis: a new avian herpesvirus. I. Biological properties.", "content": "Herpesvirus strigis: a new avian herpesvirus. I. Biological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367377"}
{"pmid": "4367380", "title": "Precipitating antibodies against maedi-visna virus in experimentally infected sheep.", "content": "Precipitating antibodies against maedi-visna virus in experimentally infected sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367380"}
{"pmid": "4367379", "title": "Nelson Bay virus. A novel reovirus.", "content": "Nelson Bay virus. A novel reovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367379"}
{"pmid": "4367381", "title": "Biological and biophysical characterization of SV40 cytoplasmic T-antigen-inducing mutants of PARA-adenovirus 7.", "content": "Biological and biophysical characterization of SV40 cytoplasmic T-antigen-inducing mutants of PARA-adenovirus 7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367381"}
{"pmid": "4367378", "title": "Composition of poliovirus fibrils.", "content": "Composition of poliovirus fibrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367378"}
{"pmid": "4367382", "title": "In vivo behaviour of a temperature-sensitive (ts) mutant of herpesvirus hominis type 2.", "content": "In vivo behaviour of a temperature-sensitive (ts) mutant of herpesvirus hominis type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367382"}
{"pmid": "4367383", "title": "Further studies on the development of Yaba poxvirus in cell culture.", "content": "Further studies on the development of Yaba poxvirus in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367383"}
{"pmid": "4367384", "title": "Infections with herpesviruses in a closed infants' community.", "content": "Infections with herpesviruses in a closed infants' community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367384"}
{"pmid": "4367385", "title": "Strain specific cell-mediated response to polyoma-transformed fibroblasts in mice.", "content": "Strain specific cell-mediated response to polyoma-transformed fibroblasts in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367385"}
{"pmid": "4367386", "title": "Rational surgery for tumors of the ovary in children.", "content": "Rational surgery for tumors of the ovary in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367386"}
{"pmid": "4367374", "title": "Brain lipid changes following hypoxia.", "content": "Brain lipid changes following hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367374"}
{"pmid": "4367390", "title": "Applications of phospholipase C in the study of membranes.", "content": "Applications of phospholipase C in the study of membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367390"}
{"pmid": "4367389", "title": "Hyperlipoproteinemia--relation to platelet lipids, platelet function and tendency to thrombosis.", "content": "Hyperlipoproteinemia--relation to platelet lipids, platelet function and tendency to thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367389"}
{"pmid": "4367393", "title": "Postsynaptic effects evoked from brain stem reticular formation in lumbar cord and their temporal correlations with a presynaptic mechanism.", "content": "Postsynaptic effects evoked from brain stem reticular formation in lumbar cord and their temporal correlations with a presynaptic mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367393"}
{"pmid": "4367399", "title": "Tonotopic organization: review and analysis.", "content": "Tonotopic organization: review and analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367399"}
{"pmid": "4367400", "title": "Cytochemical localization of cyclic nucleotide phosphodiesterase activity at developing synapses.", "content": "Cytochemical localization of cyclic nucleotide phosphodiesterase activity at developing synapses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367400"}
{"pmid": "4367401", "title": "Signal transmission through degenerating synapses in the lateral geniculate body of the cat.", "content": "Signal transmission through degenerating synapses in the lateral geniculate body of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367401"}
{"pmid": "4367402", "title": "Phosphatases in the substantia gelatinosa and motoneurones: a comparative histochemical study.", "content": "Phosphatases in the substantia gelatinosa and motoneurones: a comparative histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367402"}
{"pmid": "4367395", "title": "Inhibition studies of dehydrogenases by structural analogues of NAD.", "content": "Inhibition studies of dehydrogenases by structural analogues of NAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367395"}
{"pmid": "4367405", "title": "Binding of 3H-labelled cobra neurotoxin to cholinergic receptors in fast and slow mammalian muscles.", "content": "Binding of 3H-labelled cobra neurotoxin to cholinergic receptors in fast and slow mammalian muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367405"}
{"pmid": "4367406", "title": "Cholinergic suppression of tardive dyskinesia.", "content": "Cholinergic suppression of tardive dyskinesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367406"}
{"pmid": "4367407", "title": "Effects of methylphenidate on hyperactive children's sleep.", "content": "Effects of methylphenidate on hyperactive children's sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367407"}
{"pmid": "4367397", "title": "Treatment of respiratory distress in the newborn infant.", "content": "Treatment of respiratory distress in the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367397"}
{"pmid": "4367408", "title": "Sensory conduction of the sural nerve in polyneuropathy.", "content": "Sensory conduction of the sural nerve in polyneuropathy. Using surface electrodes, sensory nerve action potentials (SAP) have been recorded in the proximal segment (mid-calf to lateral malleolus) and the distal segment (lateral malleolus to toe 5) of the sural nerve and in the median nerve in 79 control subjects. The values obtained for the distal segment of the sural nerve varied widely and in seven apparently normal subjects no SAP could be distinguished. In the proximal segment conduction velocities were over 40 m/s and there was no significant change with age, unlike the median nerve in which a highly significant slowing occurred with age. Comparison of the results of sural and median sensory conduction studies in 300 consecutive patients screened for sensory polyneuropathy confirms the value of sural nerve sensory studies as a routine screening test, and confirms the belief that the changes in polyneuropathy are usually more prominent in lower limb nerves. It is therefore suggested that studies of sural sensory conduction form the single most useful test in the diagnosis of sensory polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367408"}
{"pmid": "4367410", "title": "Nephroblastoma in a bovine fetus.", "content": "Nephroblastoma in a bovine fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367410"}
{"pmid": "4367409", "title": "Pattern of recruiting human motor units in neuropathies and motor neurone disease.", "content": "Pattern of recruiting human motor units in neuropathies and motor neurone disease. The pattern of recruiting human motor units in the first dorsal interosseous muscle of the hand has been studied in 31 patients with ulnar neuropathies and motor neurone disease. Two years after surgical repair of an unilateral complete severance of the ulnar nerve, the twitch tensions increased to normal size. However, the normal orderly pattern of recruiting motor units of increasing size during increasing voluntary contractions was irretrievably lost. Among patients with pressure or entrapment neuropathies, the normal orderly pattern of recruiting motor units was always retained. Similarly, in patients with motor neurone disease (amyotrophic lateral sclerosis), the orderly pattern of recruitment was not disrupted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367409"}
{"pmid": "4367411", "title": "Ultrastructure of canine carotid body and aortic body tumors. Comparison with tissues of thyroid and parathyroid origin.", "content": "Ultrastructure of canine carotid body and aortic body tumors. Comparison with tissues of thyroid and parathyroid origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367411"}
{"pmid": "4367412", "title": "Ultrastructure of normal and neoplastic mast cells of the cat.", "content": "Ultrastructure of normal and neoplastic mast cells of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367412"}
{"pmid": "4367413", "title": "Aortic body tumor in a white rat.", "content": "Aortic body tumor in a white rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367413"}
{"pmid": "4367414", "title": "Cyclic adenosine-3',5'-monophosphate in cellular immunity.", "content": "Cyclic adenosine-3',5'-monophosphate in cellular immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367414"}
{"pmid": "4367416", "title": "Preliminary analysis of the effects of ATP-Mg on Escherichia coli K 12 aspartokinase I-homoserine dehydrogenase I, at low potassium concentration.", "content": "Preliminary analysis of the effects of ATP-Mg on Escherichia coli K 12 aspartokinase I-homoserine dehydrogenase I, at low potassium concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367416"}
{"pmid": "4367418", "title": "Congenital hyperphosphatasia.", "content": "Congenital hyperphosphatasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367418"}
{"pmid": "4367420", "title": "The action of barbiturates upon liver alcohol dehydrogenase. Their interference with alcohol metabolism.", "content": "The action of barbiturates upon liver alcohol dehydrogenase. Their interference with alcohol metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367420"}
{"pmid": "4367421", "title": "Action of proteolytic and glycolytic enzymes on the permeability of the blood-brain barrier.", "content": "Action of proteolytic and glycolytic enzymes on the permeability of the blood-brain barrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367421"}
{"pmid": "4367422", "title": "Activity of inactivated Burcella on murine tumors: prophylactic effects and combination with specific immunostimulation.", "content": "Activity of inactivated Burcella on murine tumors: prophylactic effects and combination with specific immunostimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367422"}
{"pmid": "4367423", "title": "Experiences with a lyophilised contagious bovine pleuropneumonia vaccine in the Ivory coast.", "content": "Experiences with a lyophilised contagious bovine pleuropneumonia vaccine in the Ivory coast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367423"}
{"pmid": "4367424", "title": "Isolation and characterization of a novel lipid, 1(3),2-diacylglyceryl-(3)-O-4'-(N,N,N-trimethyl)homoserine, from Ochromonas danica.", "content": "Isolation and characterization of a novel lipid, 1(3),2-diacylglyceryl-(3)-O-4'-(N,N,N-trimethyl)homoserine, from Ochromonas danica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367424"}
{"pmid": "4367425", "title": "Stimulation of alkaline phosphatase by analogs of inorganic pyrophosphate.", "content": "Stimulation of alkaline phosphatase by analogs of inorganic pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367425"}
{"pmid": "4367427", "title": "Magnetic resonance studies of the active-site region of thermolysin.", "content": "Magnetic resonance studies of the active-site region of thermolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367427"}
{"pmid": "4367426", "title": "Kinetic and magnetic resonance studies of the interaction of oxalate with pyruvate kinase.", "content": "Kinetic and magnetic resonance studies of the interaction of oxalate with pyruvate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367426"}
{"pmid": "4367428", "title": "Quantitative interaction of Ricinus communis agglutinin and concanavalin A with influenza and vesicular stomatitis viruses and virus-infected normal and polyoma-transformed cells.", "content": "Quantitative interaction of Ricinus communis agglutinin and concanavalin A with influenza and vesicular stomatitis viruses and virus-infected normal and polyoma-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367428"}
{"pmid": "4367429", "title": "Antibodies to the codons ApApAp, ApApC, and ApUpG.", "content": "Antibodies to the codons ApApAp, ApApC, and ApUpG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367429"}
{"pmid": "4367430", "title": "Stepwise degradation of polyribonucleotides.", "content": "Stepwise degradation of polyribonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367430"}
{"pmid": "4367431", "title": "Chemical probes of chromatin structure.", "content": "Chemical probes of chromatin structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367431"}
{"pmid": "4367432", "title": "Canine malignant mammary tumours. I. Sarcomas.", "content": "Canine malignant mammary tumours. I. Sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367432"}
{"pmid": "4367433", "title": "The relevance of the superoxide anion radical in biological systems.", "content": "The relevance of the superoxide anion radical in biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367433"}
{"pmid": "4367435", "title": "Mesenchymal tumors of the uterus.", "content": "Mesenchymal tumors of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367435"}
{"pmid": "4367434", "title": "The biological activity and the binding affinity of modified insulins determined on isolated rat fat cells.", "content": "The biological activity and the binding affinity of modified insulins determined on isolated rat fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367434"}
{"pmid": "4367436", "title": "Pathophysiology of the Fallopian tube.", "content": "Pathophysiology of the Fallopian tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367436"}
{"pmid": "4367437", "title": "Complications of regional anesthesia in obstetrics.", "content": "Complications of regional anesthesia in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367437"}
{"pmid": "4367441", "title": "Some kinetic and inhibition properties of human brain mitochondrial monoamine oxidase (EC 1.4.3.4).", "content": "Some kinetic and inhibition properties of human brain mitochondrial monoamine oxidase (EC 1.4.3.4).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367441"}
{"pmid": "4367447", "title": "Fibers projecting onto the crista ampullaris of the vertical anterior semicircular canal from other ipsilateral vestibular receptors in the frog (Rana esculenta).", "content": "Fibers projecting onto the crista ampullaris of the vertical anterior semicircular canal from other ipsilateral vestibular receptors in the frog (Rana esculenta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367447"}
{"pmid": "4367449", "title": "Malignant liver tumors in children.", "content": "Malignant liver tumors in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367449"}
{"pmid": "4367450", "title": "Effects of some coenzymes and metabolic factors on experimintal atherosclerosis in animals.", "content": "Effects of some coenzymes and metabolic factors on experimintal atherosclerosis in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367450"}
{"pmid": "4367451", "title": "Cytochrome c.", "content": "Cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367451"}
{"pmid": "4367452", "title": "Effects of 3', 5'-cyclic adenosine monophosphate, 5-hydroxytryptamine, noradrenaline and theophylline on the simultaneous release of peroxidase and amylase from the guinea pig submanibular gland.", "content": "Effects of 3', 5'-cyclic adenosine monophosphate, 5-hydroxytryptamine, noradrenaline and theophylline on the simultaneous release of peroxidase and amylase from the guinea pig submanibular gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367452"}
{"pmid": "4367454", "title": "Pituitary and plasma concentrations of adrenocorticotrophin, growth hormone, vasopressin and oxytocin in fetal and maternal sheep during the latter half of gestation and the response to haemorrhage.", "content": "Pituitary and plasma concentrations of adrenocorticotrophin, growth hormone, vasopressin and oxytocin in fetal and maternal sheep during the latter half of gestation and the response to haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367454"}
{"pmid": "4367453", "title": "Virus infections in bats.", "content": "Virus infections in bats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367453"}
{"pmid": "4367455", "title": "In vivo metabolism of 14C-labeled palmitic acid in serum and in brown and white adipose tissue of well-fed and starved newborn rabbits. II. Tracer kinetic analysis of the incorporation rate of serum free fatty acids into the main lipid fractions of brown and white adipose tissues.", "content": "In vivo metabolism of 14C-labeled palmitic acid in serum and in brown and white adipose tissue of well-fed and starved newborn rabbits. II. Tracer kinetic analysis of the incorporation rate of serum free fatty acids into the main lipid fractions of brown and white adipose tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367455"}
{"pmid": "4367457", "title": "Use of immunoperoxidase for the rapid identification of human myxoviruses and paramyxoviruses in tissue culture.", "content": "Use of immunoperoxidase for the rapid identification of human myxoviruses and paramyxoviruses in tissue culture. The immunoperoxidase method, using commercially available antisera, was compared with standard virological methods for the identification and typing of 77 isolates of human myxoviruses and paramyxoviruses. Results of typing using neutralization tests and the immunoperoxidase technique were identical for 76 of the 77 isolates. With the immunoperoxidase method there was one false negative reaction, but no false positive reactions. Cross-reactivity between influenza A (soluble) and A(2)/HK antisera with influenza A isolates was noted, but did not interfere with the interpretation of results. It is concluded that the immunoperoxidase method is ideally suited for the rapid identification and typing of common human respiratory viruses on a routine basis. It offers a number of decided advantages over both immunofluorescence and standard virological methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367457"}
{"pmid": "4367456", "title": "Unsuspected tumors in aircraft accident fatalities as a guide to evaluation of physical-examination standards.", "content": "Unsuspected tumors in aircraft accident fatalities as a guide to evaluation of physical-examination standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367456"}
{"pmid": "4367458", "title": "Biophysical-immunological assay for ribonucleic acid type C viruses.", "content": "Biophysical-immunological assay for ribonucleic acid type C viruses. A biophysical and immunological method for characterization of ribonucleic acid type C virus suspensions is described. The method provides a relationship to the total viral mass concentration of the particle titer, the gs antigen titer, and the ultraviolet absorbance (268 nm) of 2% sodium dodecyl sulfate digests. Data for murine, rat, feline, and hamster viruses are shown to be analogous within the test limitations. From these data, an assessment of the viral purity can be made, the structural integrity can be evaluated, an approximate molecular weight can be computed, and the mole ratio of gs antigen can be determined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367458"}
{"pmid": "4367462", "title": "Biosynthesis of nitrogenous phospholipids in spinach leaves.", "content": "Biosynthesis of nitrogenous phospholipids in spinach leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367462"}
{"pmid": "4367463", "title": "Preparation and properties of purified (Na+ plus K+)-stimulated mitochondrial ATPase from germinating pea seeds.", "content": "Preparation and properties of purified (Na+ plus K+)-stimulated mitochondrial ATPase from germinating pea seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367463"}
{"pmid": "4367464", "title": "Glycosphingolipids in secondary lysosomes prepared from rat liver.", "content": "Glycosphingolipids in secondary lysosomes prepared from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367464"}
{"pmid": "4367467", "title": "Ultrastructural findings in a well-differentiated hepatoma.", "content": "Ultrastructural findings in a well-differentiated hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367467"}
{"pmid": "4367468", "title": "Quantitative hepatic cytology. Experimental study.", "content": "Quantitative hepatic cytology. Experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367468"}
{"pmid": "4367471", "title": "Herpes encephalitis.", "content": "Herpes encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367471"}
{"pmid": "4367472", "title": "Electroencephalographic patterns in herpesvirus encephalitis.", "content": "Electroencephalographic patterns in herpesvirus encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367472"}
{"pmid": "4367474", "title": "Purification and partial characterization of an endonuclease from Palaemon serratus hepatopancreas.", "content": "Purification and partial characterization of an endonuclease from Palaemon serratus hepatopancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367474"}
{"pmid": "4367479", "title": "Pancreatic islet cell carcinoid: a highly malignant form of carcinoid tumor.", "content": "Pancreatic islet cell carcinoid: a highly malignant form of carcinoid tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367479"}
{"pmid": "4367480", "title": "Culturing breast tumor cells in the presence of hormones.", "content": "Culturing breast tumor cells in the presence of hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367480"}
{"pmid": "4367481", "title": "Theory of chromatography of rigid molecules on hydroxyapatite columns with small loads. I. The case when virtually all molecules are adsorbed on to a single type of crystal site through a single type of adsorption group.", "content": "Theory of chromatography of rigid molecules on hydroxyapatite columns with small loads. I. The case when virtually all molecules are adsorbed on to a single type of crystal site through a single type of adsorption group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367481"}
{"pmid": "4367482", "title": "Solitary glomus tumours of the fingers.", "content": "Solitary glomus tumours of the fingers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367482"}
{"pmid": "4367483", "title": "Proceedings: Ectopic parathyroid hormone-producing tumors.", "content": "Proceedings: Ectopic parathyroid hormone-producing tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367483"}
{"pmid": "4367484", "title": "Proceedings: An autopsy case of cholangiocarcinoma associated with pseudohyperparathyroidism.", "content": "Proceedings: An autopsy case of cholangiocarcinoma associated with pseudohyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367484"}
{"pmid": "4367486", "title": "Rescue of defective SV40 from a transformed mouse 3T3 cell line: selection of a specific defective.", "content": "Rescue of defective SV40 from a transformed mouse 3T3 cell line: selection of a specific defective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367486"}
{"pmid": "4367485", "title": "Proceedings: Effect of dibutyryl cyclic AMP on the formation of dentin and bone in parathyroidectomized rats.", "content": "Proceedings: Effect of dibutyryl cyclic AMP on the formation of dentin and bone in parathyroidectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367485"}
{"pmid": "4367487", "title": "Properties of the ts3 mutant of polyoma virus during lytic infection.", "content": "Properties of the ts3 mutant of polyoma virus during lytic infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367487"}
{"pmid": "4367488", "title": "Inhibitors of DNA synthesis: their influence on replication and transcription of simian virus 40 DNA.", "content": "Inhibitors of DNA synthesis: their influence on replication and transcription of simian virus 40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367488"}
{"pmid": "4367489", "title": "Mapping temperature-sensitive mutants of simian virus 40: rescue of mutants by fragments of viral DNA.", "content": "Mapping temperature-sensitive mutants of simian virus 40: rescue of mutants by fragments of viral DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367489"}
{"pmid": "4367490", "title": "Correlation between amino acid exchanges in coat protein of TMV mutants and the nature of the mutagens.", "content": "Correlation between amino acid exchanges in coat protein of TMV mutants and the nature of the mutagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367490"}
{"pmid": "4367491", "title": "Molecular weights of plant viral RNAs determined by gel electrophoresis under denaturing conditions.", "content": "Molecular weights of plant viral RNAs determined by gel electrophoresis under denaturing conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367491"}
{"pmid": "4367492", "title": "Regulation of synthesis of herpes simplex type 1 virus mRNA during productive infection.", "content": "Regulation of synthesis of herpes simplex type 1 virus mRNA during productive infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367492"}
{"pmid": "4367493", "title": "High specific infectivity avian RNA tumor viruses.", "content": "High specific infectivity avian RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367493"}
{"pmid": "4367494", "title": "RNA tumor viruses of pheasants: characterization of avian leukosis subgroups F and G.", "content": "RNA tumor viruses of pheasants: characterization of avian leukosis subgroups F and G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367494"}
{"pmid": "4367496", "title": "Defective interfering particles from poliovirus vaccine and vaccine reference strains.", "content": "Defective interfering particles from poliovirus vaccine and vaccine reference strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367496"}
{"pmid": "4367495", "title": "Hemagglutinating activity of bovine papilloma virus.", "content": "Hemagglutinating activity of bovine papilloma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367495"}
{"pmid": "4367497", "title": "Simian virus 40 structural proteins: amino-terminal sequence of the major capsid protein.", "content": "Simian virus 40 structural proteins: amino-terminal sequence of the major capsid protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367497"}
{"pmid": "4367498", "title": "Hybridization of simian virus 40 complementary RNA with nucleolus-associated DNA isolated from simian virus 40-transformed Chinese hamster cells.", "content": "Hybridization of simian virus 40 complementary RNA with nucleolus-associated DNA isolated from simian virus 40-transformed Chinese hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367498"}
{"pmid": "4367499", "title": "\"Huffer's\" neuropathy.", "content": "\"Huffer's\" neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367499"}
{"pmid": "4367500", "title": "A study of fine structural changes in the cartilage-to-bone transition within the developing chick vertebra.", "content": "A study of fine structural changes in the cartilage-to-bone transition within the developing chick vertebra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367500"}
{"pmid": "4367502", "title": "The control of mastitis.", "content": "The control of mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367502"}
{"pmid": "4367503", "title": "Pathogenesis of peptic ulcer.", "content": "Pathogenesis of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367503"}
{"pmid": "4367507", "title": "Effects of 6-hydroxydopamine on an identified dopamine-containing neuron in the central nervous system of Planorbis corneus.", "content": "Effects of 6-hydroxydopamine on an identified dopamine-containing neuron in the central nervous system of Planorbis corneus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367507"}
{"pmid": "4367506", "title": "Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat.", "content": "Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367506"}
{"pmid": "4367505", "title": "Depression and frequency facilitation at a synapse in Aplysia californica: evidence for regulation by availability of transmitter.", "content": "Depression and frequency facilitation at a synapse in Aplysia californica: evidence for regulation by availability of transmitter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367505"}
{"pmid": "4367508", "title": "Measurements of extracellular potassium, ECoG and pyridine nucleotide levels during cortical spreading depression in rats.", "content": "Measurements of extracellular potassium, ECoG and pyridine nucleotide levels during cortical spreading depression in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367508"}
{"pmid": "4367509", "title": "The effect of angiotensin II on neurones of the cat subfornical organ.", "content": "The effect of angiotensin II on neurones of the cat subfornical organ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367509"}
{"pmid": "4367510", "title": "Dynamic patterns of brain cell assemblies. II. Concept of dynamic patterns. Dynamic patterns in chemistry.", "content": "Dynamic patterns of brain cell assemblies. II. Concept of dynamic patterns. Dynamic patterns in chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367510"}
{"pmid": "4367511", "title": "Dynamic patterns of brain cell assemblies. II. Concept of dynamic patterns. Cell patterning.", "content": "Dynamic patterns of brain cell assemblies. II. Concept of dynamic patterns. Cell patterning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367511"}
{"pmid": "4367512", "title": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Interneuronal connectivity. Gap junction ultrastructure.", "content": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Interneuronal connectivity. Gap junction ultrastructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367512"}
{"pmid": "4367513", "title": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields and pulse distributions. Relation of neuronal waves to EEG.", "content": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields and pulse distributions. Relation of neuronal waves to EEG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367513"}
{"pmid": "4367515", "title": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields and pulse distributions. Postsynaptic events.", "content": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields and pulse distributions. Postsynaptic events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367515"}
{"pmid": "4367516", "title": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Influence of exogenous low-level currents. Electrophysiological effects of direct currents.", "content": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Influence of exogenous low-level currents. Electrophysiological effects of direct currents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367516"}
{"pmid": "4367514", "title": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields and pulse distributions. Pulse-wave problems.", "content": "Dynamic patterns of brain cell assemblies. IV. Mixed systems. Oscillating fields and pulse distributions. Pulse-wave problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367514"}
{"pmid": "4367517", "title": "Identification of viruses involved in the 1971 outbreak of hemorrhagic disease in southeastern United States white-tailed deer.", "content": "Identification of viruses involved in the 1971 outbreak of hemorrhagic disease in southeastern United States white-tailed deer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367517"}
{"pmid": "4367518", "title": "The 1971 outbreak of hemorrhagic disease among white-tailed deer of the southeastern United States.", "content": "The 1971 outbreak of hemorrhagic disease among white-tailed deer of the southeastern United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367518"}
{"pmid": "4367519", "title": "Vaccination trials in desert bighorn sheep against bluetongue virus.", "content": "Vaccination trials in desert bighorn sheep against bluetongue virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367519"}
{"pmid": "4367521", "title": "Proceedings: An attempt to localize cyclic phosphodiesterase at adrenergic nerve endings.", "content": "Proceedings: An attempt to localize cyclic phosphodiesterase at adrenergic nerve endings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367521"}
{"pmid": "4367520", "title": "Proceedings: Synaptochemistry. Outlines and scope of a discipline.", "content": "Proceedings: Synaptochemistry. Outlines and scope of a discipline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367520"}
{"pmid": "4367522", "title": "Proceedings: Effects of papaverine derivatives on cyclic 3', 5'-AMP phosphodiesterase and relaxation of rabbit ileum.", "content": "Proceedings: Effects of papaverine derivatives on cyclic 3', 5'-AMP phosphodiesterase and relaxation of rabbit ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367522"}
{"pmid": "4367523", "title": "Proceedings: Spinal transmission of autonomic processes.", "content": "Proceedings: Spinal transmission of autonomic processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367523"}
{"pmid": "4367524", "title": "Proceedings of the International Neurovegetative Symposium: Concluding remarks.", "content": "Proceedings of the International Neurovegetative Symposium: Concluding remarks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367524"}
{"pmid": "4367527", "title": "Spontaneous autoimmune diseases of domestic animals.", "content": "Spontaneous autoimmune diseases of domestic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367527"}
{"pmid": "4367526", "title": "General neuropathology of degenerative processes of the nervous system.", "content": "General neuropathology of degenerative processes of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367526"}
{"pmid": "4367528", "title": "Reactivation of chick erythrocyte nuclei by somatic cell hybridization.", "content": "Reactivation of chick erythrocyte nuclei by somatic cell hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367528"}
{"pmid": "4367529", "title": "Cyclic AMP levels in temperature sensitive SV40 transformed cell lines.", "content": "Cyclic AMP levels in temperature sensitive SV40 transformed cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367529"}
{"pmid": "4367532", "title": "Studies on a Chinese hamster line that is temperature sensitive for the commitment to DNA synthesis.", "content": "Studies on a Chinese hamster line that is temperature sensitive for the commitment to DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367532"}
{"pmid": "4367530", "title": "Calcium transport in isolated bone cells. I. Bone cell isolation procedures.", "content": "Calcium transport in isolated bone cells. I. Bone cell isolation procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367530"}
{"pmid": "4367531", "title": "Calcium transport in isolated bone cells. II. Calcium transport studies.", "content": "Calcium transport in isolated bone cells. II. Calcium transport studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367531"}
{"pmid": "4367533", "title": "Comparative study of various methods for the extraction of free creatine and phosphocreatine from mouse skeletal muscle.", "content": "Comparative study of various methods for the extraction of free creatine and phosphocreatine from mouse skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367533"}
{"pmid": "4367534", "title": "An assay for protein activity on polyacrylamide gels.", "content": "An assay for protein activity on polyacrylamide gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367534"}
{"pmid": "4367535", "title": "Quantitative measurement of hypermodified adenosine ribonucleosides in plant tissues.", "content": "Quantitative measurement of hypermodified adenosine ribonucleosides in plant tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367535"}
{"pmid": "4367536", "title": "A new rapid assay for measuring deoxycytidylate- and deoxythymidylate-kinase activities.", "content": "A new rapid assay for measuring deoxycytidylate- and deoxythymidylate-kinase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367536"}
{"pmid": "4367537", "title": "Acetonitrile-based solvents: their application in thin-layer chromatography of cyclic nucleotides, nucleosides, purine, and pyrimidines.", "content": "Acetonitrile-based solvents: their application in thin-layer chromatography of cyclic nucleotides, nucleosides, purine, and pyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367537"}
{"pmid": "4367538", "title": "Experimental herpetic keratitis in the guinea pig.", "content": "Experimental herpetic keratitis in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367538"}
{"pmid": "4367540", "title": "Characteristics and distribution of spinal focal synaptic potentials generated by group II muscle afferents.", "content": "Characteristics and distribution of spinal focal synaptic potentials generated by group II muscle afferents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367540"}
{"pmid": "4367541", "title": "Studies on the postnatal development of the collecting ducts of the rat kidney, with particular reference to their glycogen content.", "content": "Studies on the postnatal development of the collecting ducts of the rat kidney, with particular reference to their glycogen content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367541"}
{"pmid": "4367542", "title": "Ascorbic acid as an antioxidant in thin-layer chromatography of corticosteroids.", "content": "Ascorbic acid as an antioxidant in thin-layer chromatography of corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367542"}
{"pmid": "4367543", "title": "Separation of phosphatidyl inositomannosides of Mycobacteria.", "content": "Separation of phosphatidyl inositomannosides of Mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367543"}
{"pmid": "4367545", "title": "Retinal lesions in rat after treatment with chlorphentermine or with tricyclic antidepressants.", "content": "Retinal lesions in rat after treatment with chlorphentermine or with tricyclic antidepressants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367545"}
{"pmid": "4367546", "title": "Bone marking and lead intoxication. Early pathological changes in osteoclasts.", "content": "Bone marking and lead intoxication. Early pathological changes in osteoclasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367546"}
{"pmid": "4367544", "title": "Lipidosis-like cellular alterations in lymphatic tissues of chlorphentermine-treated animals.", "content": "Lipidosis-like cellular alterations in lymphatic tissues of chlorphentermine-treated animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367544"}
{"pmid": "4367547", "title": "An ultrastructural analysis of early fertilization in the sand dollar, Echinarachnius parma.", "content": "An ultrastructural analysis of early fertilization in the sand dollar, Echinarachnius parma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367547"}
{"pmid": "4367548", "title": "Electron microscopic investigation of synaptic organization of the trochlear nucleus in cat. I. Normal ultrastructure.", "content": "Electron microscopic investigation of synaptic organization of the trochlear nucleus in cat. I. Normal ultrastructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367548"}
{"pmid": "4367551", "title": "Clinicopathological conference: Exanthem and pneumonia in a 3-year-old girl.", "content": "Clinicopathological conference: Exanthem and pneumonia in a 3-year-old girl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367551"}
{"pmid": "4367552", "title": "Circumscribed \"giant-cell\" glioblastoma.", "content": "Circumscribed \"giant-cell\" glioblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367552"}
{"pmid": "4367553", "title": "Giant cell hepatitis with cytomegalovirus inclusions in an adult. A case report.", "content": "Giant cell hepatitis with cytomegalovirus inclusions in an adult. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367553"}
{"pmid": "4367554", "title": "Plasma angiotensin-like activity in hypertension.", "content": "Plasma angiotensin-like activity in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367554"}
{"pmid": "4367559", "title": "The use of solid medium cultures for the removal of bacteria and fungi from Entamoeba histolytica strains.", "content": "The use of solid medium cultures for the removal of bacteria and fungi from Entamoeba histolytica strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367559"}
{"pmid": "4367560", "title": "Studies on the effect of inactivated viruses on the growth of Poxvirus variolae. I. The influence of heating at temperatures: 70 degrees C, 56 degrees C and 37 degrees C on the infection activity of some viruses.", "content": "Studies on the effect of inactivated viruses on the growth of Poxvirus variolae. I. The influence of heating at temperatures: 70 degrees C, 56 degrees C and 37 degrees C on the infection activity of some viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367560"}
{"pmid": "4367561", "title": "Syncytium formation of Japanese quail embryo fibroblasts on double infection with Rous sarcoma virus and measles virus.", "content": "Syncytium formation of Japanese quail embryo fibroblasts on double infection with Rous sarcoma virus and measles virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367561"}
{"pmid": "4367562", "title": "Primary tissue culture of brain tumor using glass fiber.", "content": "Primary tissue culture of brain tumor using glass fiber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367562"}
{"pmid": "4367563", "title": "Vincristine sulphate in the postoperative management of malignant supratentorial glioma.", "content": "Vincristine sulphate in the postoperative management of malignant supratentorial glioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367563"}
{"pmid": "4367564", "title": "Combined use of trimethoprim plus superseptyl and of trimethoprim plus superseptyl plus polymyxin B in Salmonella infections.", "content": "Combined use of trimethoprim plus superseptyl and of trimethoprim plus superseptyl plus polymyxin B in Salmonella infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367564"}
{"pmid": "4367566", "title": "[Mechanism of action and cellular receptors of insulin (author's transl)].", "content": "[Mechanism of action and cellular receptors of insulin (author's transl)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367566"}
{"pmid": "4367574", "title": "The primary structure of DNA.", "content": "The primary structure of DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367574"}
{"pmid": "4367575", "title": "Variola virus in the throat of healthy contacts of small-pox cases.", "content": "Variola virus in the throat of healthy contacts of small-pox cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367575"}
{"pmid": "4367577", "title": "Treatment and prophylaxis in food handling amoebic cyst carriers.", "content": "Treatment and prophylaxis in food handling amoebic cyst carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367577"}
{"pmid": "4367578", "title": "A specific method for the assay of alcohol dehydrogenase in human liver and serum.", "content": "A specific method for the assay of alcohol dehydrogenase in human liver and serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367578"}
{"pmid": "4367580", "title": "Identification and quantitative determination of 2-hydroxyoestriol in human late-pregnancy urine.", "content": "Identification and quantitative determination of 2-hydroxyoestriol in human late-pregnancy urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367580"}
{"pmid": "4367581", "title": "Steroid metabolism in testis tissue: concentrations of unconjugated and sulfated neutral steroids in boar testis.", "content": "Steroid metabolism in testis tissue: concentrations of unconjugated and sulfated neutral steroids in boar testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367581"}
{"pmid": "4367582", "title": "Ligand specificity of progesterone-binding proteins in guinea pig and sheep.", "content": "Ligand specificity of progesterone-binding proteins in guinea pig and sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367582"}
{"pmid": "4367583", "title": "Physiological variations in plasma testosterone in normal adult male subjects measured by a competitive protein-binding technique.", "content": "Physiological variations in plasma testosterone in normal adult male subjects measured by a competitive protein-binding technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367583"}
{"pmid": "4367584", "title": "Simultaneous determination of cortisol, deoxycortisol and corticosterone in plasma and urine by competitive protein binding assay. Response of normal subjects to ACTH and metyrapone.", "content": "Simultaneous determination of cortisol, deoxycortisol and corticosterone in plasma and urine by competitive protein binding assay. Response of normal subjects to ACTH and metyrapone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367584"}
{"pmid": "4367585", "title": "Binding of progesterone by rat myometrium during pregnancy and by human myometrium in late pregnancy.", "content": "Binding of progesterone by rat myometrium during pregnancy and by human myometrium in late pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367585"}
{"pmid": "4367586", "title": "Characterization of a specific androgen receptor in rat prostate cytosol by agargel electrophoresis. In vivo and in vitro studies.", "content": "Characterization of a specific androgen receptor in rat prostate cytosol by agargel electrophoresis. In vivo and in vitro studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367586"}
{"pmid": "4367587", "title": "Blood coagulation and fibrinolysis in Ugandan patients with cirrhosis and hepatocellular carcinoma.", "content": "Blood coagulation and fibrinolysis in Ugandan patients with cirrhosis and hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367587"}
{"pmid": "4367591", "title": "Carriers and specificity in membranes. 3. Carrier-facilitated transport. Molecular motion in phospholipid bilayers and biomembranes.", "content": "Carriers and specificity in membranes. 3. Carrier-facilitated transport. Molecular motion in phospholipid bilayers and biomembranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367591"}
{"pmid": "4367592", "title": "Carriers and specificity in membranes. V. Neuron membranes. Membrane phenomena at the synapse.", "content": "Carriers and specificity in membranes. V. Neuron membranes. Membrane phenomena at the synapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367592"}
{"pmid": "4367593", "title": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 2. Tilorone and related bis-basic ethers of fluorenone, fluorenol, and fluorene.", "content": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 2. Tilorone and related bis-basic ethers of fluorenone, fluorenol, and fluorene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367593"}
{"pmid": "4367594", "title": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 3. 2,7-Bis(aminoacyl)fluorenes and -fluorenones.", "content": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 3. 2,7-Bis(aminoacyl)fluorenes and -fluorenones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367594"}
{"pmid": "4367595", "title": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 4. Bis-basic sulfonamides of anthraquinone.", "content": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 4. Bis-basic sulfonamides of anthraquinone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367595"}
{"pmid": "4367596", "title": "The enzymology of cholesterol esterification.", "content": "The enzymology of cholesterol esterification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367596"}
{"pmid": "4367597", "title": "Phospholipid substrate specificity of purified human plasma lecithin:cholesterol acyltransferase.", "content": "Phospholipid substrate specificity of purified human plasma lecithin:cholesterol acyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367597"}
{"pmid": "4367598", "title": "Cholesterol esterification by the rat liver Golgi apparatus.", "content": "Cholesterol esterification by the rat liver Golgi apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367598"}
{"pmid": "4367599", "title": "Studies on enzymatic and molecular properties of lecithin:cholesterol acyltransferase.", "content": "Studies on enzymatic and molecular properties of lecithin:cholesterol acyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367599"}
{"pmid": "4367601", "title": "Lecithin: cholesterol acyltransferase of human plasma. Role of chylomicrons, very low, and high density lipoproteins in the reaction.", "content": "Lecithin: cholesterol acyltransferase of human plasma. Role of chylomicrons, very low, and high density lipoproteins in the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367601"}
{"pmid": "4367600", "title": "In vitro determination of lecithin:cholesterol acyltransferase in plasma.", "content": "In vitro determination of lecithin:cholesterol acyltransferase in plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367600"}
{"pmid": "4367602", "title": "Factors determining the concentrations of lysolecithin in plasma and tissues.", "content": "Factors determining the concentrations of lysolecithin in plasma and tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367602"}
{"pmid": "4367603", "title": "Degradation of high-density lipoproteins (HDL) in vitro.", "content": "Degradation of high-density lipoproteins (HDL) in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367603"}
{"pmid": "4367605", "title": "Isoelectric fractionation of plasma high-density lipoproteins.", "content": "Isoelectric fractionation of plasma high-density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367605"}
{"pmid": "4367604", "title": "Human plasma high-density lipoprotein composition during the menstrual cycle.", "content": "Human plasma high-density lipoprotein composition during the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367604"}
{"pmid": "4367607", "title": "Apolipoproteins and lipoprotein families in familial lecithin: cholesterol acyltransferase deficiency.", "content": "Apolipoproteins and lipoprotein families in familial lecithin: cholesterol acyltransferase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367607"}
{"pmid": "4367608", "title": "Familial lecithin:cholesterol acyltransferase deficiency. Studies on lipid composition and morphology of tissues.", "content": "Familial lecithin:cholesterol acyltransferase deficiency. Studies on lipid composition and morphology of tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367608"}
{"pmid": "4367606", "title": "Familial lecithin:cholesterol acyltransferase deficiency--a clinical survey.", "content": "Familial lecithin:cholesterol acyltransferase deficiency--a clinical survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367606"}
{"pmid": "4367609", "title": "Familial lecithin:cholesterol acyltransferase deficiency. Report of a third Norwegian family with two afflicted members.", "content": "Familial lecithin:cholesterol acyltransferase deficiency. Report of a third Norwegian family with two afflicted members.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367609"}
{"pmid": "4367610", "title": "Lipid and lipoprotein abnormalities in liver disease: the possible role of lecithin: cholesterol acyltransferase deficiency.", "content": "Lipid and lipoprotein abnormalities in liver disease: the possible role of lecithin: cholesterol acyltransferase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367610"}
{"pmid": "4367612", "title": "Plasma cholesterol esterification in vivo in man.", "content": "Plasma cholesterol esterification in vivo in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367612"}
{"pmid": "4367611", "title": "Structural studies on serum lipoproteins in homozygotes and heterozygotes for the lecithin:cholesterol acyltransferase deficiency gene.", "content": "Structural studies on serum lipoproteins in homozygotes and heterozygotes for the lecithin:cholesterol acyltransferase deficiency gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367611"}
{"pmid": "4367613", "title": "Current concepts of cholesterol metabolism and their relationship to lecithin:cholesterol acyltransferase.", "content": "Current concepts of cholesterol metabolism and their relationship to lecithin:cholesterol acyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367613"}
{"pmid": "4367614", "title": "Plasma lipoprotein metabolism in familial lecithin:cholesterol acyltransferase deficiency.", "content": "Plasma lipoprotein metabolism in familial lecithin:cholesterol acyltransferase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367614"}
{"pmid": "4367621", "title": "Milk inhalation pneumonia: the significance of fat filled macrophages in tracheal secretions.", "content": "Milk inhalation pneumonia: the significance of fat filled macrophages in tracheal secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367621"}
{"pmid": "4367623", "title": "Clinicopathologic conference: Coexistent congenital cytomegalovirus and toxoplasmosis in a newborn infant.", "content": "Clinicopathologic conference: Coexistent congenital cytomegalovirus and toxoplasmosis in a newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367623"}
{"pmid": "4367624", "title": "Bronchogenic carcinoma.", "content": "Bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367624"}
{"pmid": "4367628", "title": "Oxidative haemolysis and Heinz body haemolytic anaemia.", "content": "Oxidative haemolysis and Heinz body haemolytic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367628"}
{"pmid": "4367629", "title": "Delayed incorporation of (75Se)selenomethionine into fibrinogen: its effect upon kinetic studies of fibrinogen with (75Se)selenomethionine in rabbits.", "content": "Delayed incorporation of (75Se)selenomethionine into fibrinogen: its effect upon kinetic studies of fibrinogen with (75Se)selenomethionine in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367629"}
{"pmid": "4367630", "title": "Neuromuscular blocking action of an alkylating local anaesthetic: site of action and effects of temperature and calcium ions.", "content": "Neuromuscular blocking action of an alkylating local anaesthetic: site of action and effects of temperature and calcium ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367630"}
{"pmid": "4367631", "title": "Genetic complementation after fusion of Tay-Sachs and Sandhoff cells.", "content": "Genetic complementation after fusion of Tay-Sachs and Sandhoff cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367631"}
{"pmid": "4367632", "title": "Solvent exposure of specific nuclei of angiotensin II determined by NMR solvent saturation method.", "content": "Solvent exposure of specific nuclei of angiotensin II determined by NMR solvent saturation method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367632"}
{"pmid": "4367633", "title": "Analysis of specificity of antibodies contained in antiserum against poliovirus with mutants resistant to inhibitors in equine serum.", "content": "Analysis of specificity of antibodies contained in antiserum against poliovirus with mutants resistant to inhibitors in equine serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367633"}
{"pmid": "4367634", "title": "On-filter analysis of quartz in respirable coal dust by infrared absorption and X-ray diffraction.", "content": "On-filter analysis of quartz in respirable coal dust by infrared absorption and X-ray diffraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367634"}
{"pmid": "4367635", "title": "Therapeutic action of antimicrobial agents in localized infections of mice.", "content": "Therapeutic action of antimicrobial agents in localized infections of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367635"}
{"pmid": "4367636", "title": "Comparative evaluation of cyclacillin and ampicillin in urinary tract infections. A double-blind study.", "content": "Comparative evaluation of cyclacillin and ampicillin in urinary tract infections. A double-blind study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367636"}
{"pmid": "4367637", "title": "Pre- and postoperative treatment of chronic multiresistant cases of pulmonary tuberculosis with rifampicin.", "content": "Pre- and postoperative treatment of chronic multiresistant cases of pulmonary tuberculosis with rifampicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367637"}
{"pmid": "4367639", "title": "Atypical warts in cattle.", "content": "Atypical warts in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367639"}
{"pmid": "4367641", "title": "Biochemical characteristics of mammalian brain 5-hydroxytryptophan decarboxylase activity.", "content": "Biochemical characteristics of mammalian brain 5-hydroxytryptophan decarboxylase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367641"}
{"pmid": "4367640", "title": "Ulcerative esophagitis associated with poxvirus infection in a calf.", "content": "Ulcerative esophagitis associated with poxvirus infection in a calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367640"}
{"pmid": "4367642", "title": "Role of active transport of tryptophan in the control of 5-hydroxytryptamine biosynthesis.", "content": "Role of active transport of tryptophan in the control of 5-hydroxytryptamine biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367642"}
{"pmid": "4367644", "title": "On the effects of melatonin on sleep and behavior in man.", "content": "On the effects of melatonin on sleep and behavior in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367644"}
{"pmid": "4367643", "title": "The role of serotonin in the regulation of a phasic event of rapid eye movement sleep: the ponto-geniculo-occipital wave.", "content": "The role of serotonin in the regulation of a phasic event of rapid eye movement sleep: the ponto-geniculo-occipital wave.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367643"}
{"pmid": "4367645", "title": "Ventricular fluid 5-hydroxyindoleacetic acid concentrations during human sleep.", "content": "Ventricular fluid 5-hydroxyindoleacetic acid concentrations during human sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367645"}
{"pmid": "4367646", "title": "Effects of central alterations of serotoninergic neurons upon the sleep-waking cycle.", "content": "Effects of central alterations of serotoninergic neurons upon the sleep-waking cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367646"}
{"pmid": "4367647", "title": "Opposite effects of serotonin and dopamine on copulatory activation in castrated male rats.", "content": "Opposite effects of serotonin and dopamine on copulatory activation in castrated male rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367647"}
{"pmid": "4367648", "title": "Melatonin: effects on brain function.", "content": "Melatonin: effects on brain function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367648"}
{"pmid": "4367649", "title": "Serotonergic-dopaminergic interactions and extrapyramidal function.", "content": "Serotonergic-dopaminergic interactions and extrapyramidal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367649"}
{"pmid": "4367650", "title": "Radioimmunoassay of porcine FSH.", "content": "Radioimmunoassay of porcine FSH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367650"}
{"pmid": "4367654", "title": "The pathogenesis of recurrent infections with infectious bovine rhinotracheitis virus induced in calves by treatment with corticosteroids.", "content": "The pathogenesis of recurrent infections with infectious bovine rhinotracheitis virus induced in calves by treatment with corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367654"}
{"pmid": "4367655", "title": "An outbreak of bovine cutaneous fibropapillomas following dehorning.", "content": "An outbreak of bovine cutaneous fibropapillomas following dehorning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367655"}
{"pmid": "4367657", "title": "Americans love hogwash.", "content": "Americans love hogwash.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367657"}
{"pmid": "4367658", "title": "Megavitamin and orthomolecular therapy in psychiatry.", "content": "Megavitamin and orthomolecular therapy in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367658"}
{"pmid": "4367659", "title": "Radioiodine metabolism in endemic goitre in Nigeria. (Significance of the perchlorate discharge test).", "content": "Radioiodine metabolism in endemic goitre in Nigeria. (Significance of the perchlorate discharge test).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367659"}
{"pmid": "4367660", "title": "Advantages of intertrochanteric osteotomy in osteoarthrosis of the hip.", "content": "Advantages of intertrochanteric osteotomy in osteoarthrosis of the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367660"}
{"pmid": "4367661", "title": "Case report: pseudo-tumor of the liver in hepatitis.", "content": "Case report: pseudo-tumor of the liver in hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367661"}
{"pmid": "4367662", "title": "The use of the Langner's Psychiatric Impairment Scale in a student health service.", "content": "The use of the Langner's Psychiatric Impairment Scale in a student health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367662"}
{"pmid": "4367664", "title": "Group after-care for employed problem drinkers.", "content": "Group after-care for employed problem drinkers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367664"}
{"pmid": "4367666", "title": "Cosmetics: is new legislation needed?", "content": "Cosmetics: is new legislation needed?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367666"}
{"pmid": "4367663", "title": "Administrative relationships between maternal and child health programs and family planning programs in health departments--1973.", "content": "Administrative relationships between maternal and child health programs and family planning programs in health departments--1973.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367663"}
{"pmid": "4367667", "title": "Cosmetics: marketing practices and the Federal Trade Commission.", "content": "Cosmetics: marketing practices and the Federal Trade Commission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367667"}
{"pmid": "4367669", "title": "Remarks on proposed cosmetic legislation pending in Congress.", "content": "Remarks on proposed cosmetic legislation pending in Congress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367669"}
{"pmid": "4367668", "title": "Cosmetic legislation: the need.", "content": "Cosmetic legislation: the need.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367668"}
{"pmid": "4367671", "title": "Inactivation of poliovirus in water by ozonation.", "content": "Inactivation of poliovirus in water by ozonation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367671"}
{"pmid": "4367674", "title": "Inhibition of replication of vesicular stomatitis virus in mouse embryonic cell culture infected with Japanese encephalitis virus.", "content": "Inhibition of replication of vesicular stomatitis virus in mouse embryonic cell culture infected with Japanese encephalitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367674"}
{"pmid": "4367665", "title": "A treatment for cold sores.", "content": "A treatment for cold sores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367665"}
{"pmid": "4367686", "title": "Antiviral effect of 3, 4-dihydro-1-isoquinolineacetamide hydrochloride in experimental human rhinovirus infection.", "content": "Antiviral effect of 3, 4-dihydro-1-isoquinolineacetamide hydrochloride in experimental human rhinovirus infection. Double-blind trials were conducted in volunteers to evaluate the efficacy of the prophylactic 3,4-dihydro-1-isoquinolineacetamide hydrochloride (DIQA) treatment against rhinovirus type 24 challenge. Ten men received a 7-day course of DIQA treatment and 11 men received a placebo. The intranasal viral challenge dose was 10 mean tissue culture infective doses. The oral administration of 1 g prechallenge and 2 g a day for 6 consecutive postchallenge days did not prevent the development of colds. Nine drug-treated men and 10 controls developed rhinovirus illness. However, the illnesses of the drug-treated men were mild. Rhinorrhea occurred less frequently and was more mild in the drug-treated group. The challenge virus was recovered from 80% of these subjects in both groups, but almost twice the number of challenge viruses were isolated from the controls than from the drug-treated men. The prophylactic DIQA therapy appears to suppress the cold syndrome and to reduce virus excretion, although its effect is marginal. Additional clinical trials are warranted to confirm the antirhinoviral effect of this drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367686"}
{"pmid": "4367687", "title": "Review of the functional neuromuscular transmission unit.", "content": "Review of the functional neuromuscular transmission unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367687"}
{"pmid": "4367688", "title": "Rehabilitation through team effort.", "content": "Rehabilitation through team effort.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367688"}
{"pmid": "4367694", "title": "Testosterone-activated copulatory behavior in the castrated male rat.", "content": "Testosterone-activated copulatory behavior in the castrated male rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367694"}
{"pmid": "4367696", "title": "Fetal influences on myometrial contractility.", "content": "Fetal influences on myometrial contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367696"}
{"pmid": "4367698", "title": "Embryonic antigen expression on experimental rat tumours.", "content": "Embryonic antigen expression on experimental rat tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367698"}
{"pmid": "4367701", "title": "Myasthenia gravis.", "content": "Myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367701"}
{"pmid": "4367704", "title": "Bronchogenic carcinoma in the presence of heart disease: a diagnostic dilemma.", "content": "Bronchogenic carcinoma in the presence of heart disease: a diagnostic dilemma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367704"}
{"pmid": "4367705", "title": "Changes in 32P-content of phosphatidic acid and the phosphoinositides of rabbit platelets during aggregation induced by collagen or thrombin.", "content": "Changes in 32P-content of phosphatidic acid and the phosphoinositides of rabbit platelets during aggregation induced by collagen or thrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367705"}
{"pmid": "4367706", "title": "Histochemical findings on preleukemic states.", "content": "Histochemical findings on preleukemic states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367706"}
{"pmid": "4367707", "title": "Nitroxides. 58. Structure of steroidal spin labels.", "content": "Nitroxides. 58. Structure of steroidal spin labels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367707"}
{"pmid": "4367708", "title": "Ornithine decarboxylase turnover slowed by alpha-hydrazino-ornithine.", "content": "Ornithine decarboxylase turnover slowed by alpha-hydrazino-ornithine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367708"}
{"pmid": "4367710", "title": "ACTH and alpha-MSH: cardiovascular and antiarrhythmic properties.", "content": "ACTH and alpha-MSH: cardiovascular and antiarrhythmic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367710"}
{"pmid": "4367709", "title": "The influence of dichlorodiphenyltrichloroethane, polychlorinated biphenyls and anionic amphiphilic compounds on stabilization of sodium- and potassium-activated adenosine triphosphatases by acidic phospholipids.", "content": "The influence of dichlorodiphenyltrichloroethane, polychlorinated biphenyls and anionic amphiphilic compounds on stabilization of sodium- and potassium-activated adenosine triphosphatases by acidic phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367709"}
{"pmid": "4367712", "title": "Increasing the resistance of carp to dropsy by breeding. I. Methods of breeding for resistance.", "content": "Increasing the resistance of carp to dropsy by breeding. I. Methods of breeding for resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367712"}
{"pmid": "4367713", "title": "Genetic control of the sensitivity of Aspergillus nidulans to mutagenic factors. II. The sensitivity of uvs mutants to different mutagenic factors.", "content": "Genetic control of the sensitivity of Aspergillus nidulans to mutagenic factors. II. The sensitivity of uvs mutants to different mutagenic factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367713"}
{"pmid": "4367717", "title": "5-Hydroxytryptamine and sleep in the cat: a brief overview.", "content": "5-Hydroxytryptamine and sleep in the cat: a brief overview.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367717"}
{"pmid": "4367719", "title": "Characteristics of a novel serum vitamin-B12-binding protein associated with hepatocellular carcinoma.", "content": "Characteristics of a novel serum vitamin-B12-binding protein associated with hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367719"}
{"pmid": "4367720", "title": "Proceedings: The release of plasminogen activator and factor VIII to lysine vasopressin, arginine vasopressin, I-desamino-8-d-arginine vasopressin, angiotensin and oxytocin in man.", "content": "Proceedings: The release of plasminogen activator and factor VIII to lysine vasopressin, arginine vasopressin, I-desamino-8-d-arginine vasopressin, angiotensin and oxytocin in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367720"}
{"pmid": "4367721", "title": "Glucose intolerance in mice infected with encephalomyocarditis virus.", "content": "Glucose intolerance in mice infected with encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367721"}
{"pmid": "4367722", "title": "Steroid studies in a case of ovarian hyperluteinization with virilism in two consecutive pregnancies.", "content": "Steroid studies in a case of ovarian hyperluteinization with virilism in two consecutive pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367722"}
{"pmid": "4367724", "title": "Growth of a new fiber projection in the brain of adult rats: Re-innervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions.", "content": "Growth of a new fiber projection in the brain of adult rats: Re-innervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367724"}
{"pmid": "4367725", "title": "Isolation of synaptic plasma membrane from brain by combined flotation-sedimentation density gradient centrifugation.", "content": "Isolation of synaptic plasma membrane from brain by combined flotation-sedimentation density gradient centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367725"}
{"pmid": "4367726", "title": "Affinity chromatography of beta-hydroxybutyrate dehydrogenase on Nad and hydrophobic chain derivatives of sepharose.", "content": "Affinity chromatography of beta-hydroxybutyrate dehydrogenase on Nad and hydrophobic chain derivatives of sepharose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367726"}
{"pmid": "4367727", "title": "Nine disease outbreaks associated with myxoviruses among ducks in Hong Kong.", "content": "Nine disease outbreaks associated with myxoviruses among ducks in Hong Kong.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367727"}
{"pmid": "4367728", "title": "Effects of phosphate on the dissociation and enzymic stability of rabbit muscle lactate dehydrogenase.", "content": "Effects of phosphate on the dissociation and enzymic stability of rabbit muscle lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367728"}
{"pmid": "4367729", "title": "Covalent attachment of fluorescent groups to transfer ribonucleic acid. Reactions with 4-bromomethyl-7-methoxy-2-oxo-2H-benzopyran.", "content": "Covalent attachment of fluorescent groups to transfer ribonucleic acid. Reactions with 4-bromomethyl-7-methoxy-2-oxo-2H-benzopyran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367729"}
{"pmid": "4367730", "title": "The vitamin-E-deficiency syndrome in pigs. 3. Light- and electron microscopic studies on myocardial vascular injuty.", "content": "The vitamin-E-deficiency syndrome in pigs. 3. Light- and electron microscopic studies on myocardial vascular injuty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367730"}
{"pmid": "4367731", "title": "Canary pox in sparrows and canaries (Fringillidae and in weavers (Ploceidae). Pathology and host specificity of the virus.", "content": "Canary pox in sparrows and canaries (Fringillidae and in weavers (Ploceidae). Pathology and host specificity of the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367731"}
{"pmid": "4367732", "title": "Cushing's syndrome secondary to ACTH-secreting Wilms' tumor.", "content": "Cushing's syndrome secondary to ACTH-secreting Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367732"}
{"pmid": "4367733", "title": "Coenzyme contents of arterial tissue.", "content": "Coenzyme contents of arterial tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367733"}
{"pmid": "4367734", "title": "Dissolution and removal of neuronal lipofuscin following dimethylaminoethyl p-chlorophenoxyacetate administration to guinea pigs.", "content": "Dissolution and removal of neuronal lipofuscin following dimethylaminoethyl p-chlorophenoxyacetate administration to guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367734"}
{"pmid": "4367740", "title": "IBR virus isolated from two epizootics in Mexican dairy cattle.", "content": "IBR virus isolated from two epizootics in Mexican dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367740"}
{"pmid": "4367742", "title": "Food faddism.", "content": "Food faddism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367742"}
{"pmid": "4367741", "title": "Letter: Ferroxidase I and II.", "content": "Letter: Ferroxidase I and II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367741"}
{"pmid": "4367737", "title": "Swellings of the salivary glands. I. Non-neoplastic enlargements.", "content": "Swellings of the salivary glands. I. Non-neoplastic enlargements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367737"}
{"pmid": "4367743", "title": "Investigation of some biochemical genetic markers in four endogamous groups in Panjab (N.W. India). II. Red cell enzyme polymorphisms.", "content": "Investigation of some biochemical genetic markers in four endogamous groups in Panjab (N.W. India). II. Red cell enzyme polymorphisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367743"}
{"pmid": "4367745", "title": "The turnover rate of serum glycerides in the lipoproteins of fasting obese women during weight loss.", "content": "The turnover rate of serum glycerides in the lipoproteins of fasting obese women during weight loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367745"}
{"pmid": "4367746", "title": "Aspects of experimental hepatocarcinogenesis. V. Ultrastructural morpholgy of early hepatocellular carcinomas.", "content": "Aspects of experimental hepatocarcinogenesis. V. Ultrastructural morpholgy of early hepatocellular carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367746"}
{"pmid": "4367748", "title": "Vascular problems in upper abdominal cancer surgery.", "content": "Vascular problems in upper abdominal cancer surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367748"}
{"pmid": "4367747", "title": "Primary liver tumors in infancy and childhood. 41 cases variously treated.", "content": "Primary liver tumors in infancy and childhood. 41 cases variously treated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367747"}
{"pmid": "4367750", "title": "The Lockerbie road accident after-care scheme.", "content": "The Lockerbie road accident after-care scheme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367750"}
{"pmid": "4367749", "title": "Bronchial carcinoma treated by adjuvant cancer chemotherapy.", "content": "Bronchial carcinoma treated by adjuvant cancer chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367749"}
{"pmid": "4367752", "title": "Endocrine changes before and after the menarche. I. Urinary excretion of estrogen, FSH and LH, and serum levels of progesterone, FSH and LH.", "content": "Endocrine changes before and after the menarche. I. Urinary excretion of estrogen, FSH and LH, and serum levels of progesterone, FSH and LH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367752"}
{"pmid": "4367754", "title": "Papaverine, a potent inhibitor of respiration in C-6 astrocytoma cells.", "content": "Papaverine, a potent inhibitor of respiration in C-6 astrocytoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367754"}
{"pmid": "4367753", "title": "Enhancement of the activity of angiotensin II by certain cations.", "content": "Enhancement of the activity of angiotensin II by certain cations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367753"}
{"pmid": "4367755", "title": "Products, requirements and efficiency of biosynthesis: a quantitative approach.", "content": "Products, requirements and efficiency of biosynthesis: a quantitative approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367755"}
{"pmid": "4367757", "title": "Formation and biologic role of polyoma virus-antibody complexes. A critical role for complement.", "content": "Formation and biologic role of polyoma virus-antibody complexes. A critical role for complement. Interaction of polyoma virus, specific antibody, and complement has been studied. Firm evidence has been gathered that C1 through C3 and not C5 through C9 enhance neutralization of virus-antiviral antibody (V-Ab) complexes. C enhancement of neutralization occurs primarily by agglutination of V-Ab complexes and not by virion lysis or attachment of large protein molecules to the V-Ab complex. In this model, binding of C1, 4, 2, 3 to the V-Ab complex may explain why some viruses concentrate in or infect certain cells bearing C3 receptors such as B lymphocytes, macrophages, and monocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367757"}
{"pmid": "4367759", "title": "Expression of mammary tumor virus antigen on the membranes of lymphoid cells.", "content": "Expression of mammary tumor virus antigen on the membranes of lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367759"}
{"pmid": "4367758", "title": "Inhibition of leukocyte migration by human tumors. Effect on patient survival.", "content": "Inhibition of leukocyte migration by human tumors. Effect on patient survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367758"}
{"pmid": "4367760", "title": "Carcinogenic and hepatotoxic effects of diethylnitrosamine in hedgehogs.", "content": "Carcinogenic and hepatotoxic effects of diethylnitrosamine in hedgehogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367760"}
{"pmid": "4367761", "title": "Cancer control in Yugoslavia.", "content": "Cancer control in Yugoslavia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367761"}
{"pmid": "4367763", "title": "Studies on the effect of fructose diphosphatase on phosphofructokinase.", "content": "Studies on the effect of fructose diphosphatase on phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367763"}
{"pmid": "4367762", "title": "Possible viral etiology of human cancer.", "content": "Possible viral etiology of human cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367762"}
{"pmid": "4367764", "title": "Differential effects of pentylenetetrazol on REM sleep in naive and cobalt-epileptic rats.", "content": "Differential effects of pentylenetetrazol on REM sleep in naive and cobalt-epileptic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367764"}
{"pmid": "4367765", "title": "Cytoplasmic inclusions in urinary bladder epithelium of the rhesus monkey. A histochemical, light-and electron-microscopic study.", "content": "Cytoplasmic inclusions in urinary bladder epithelium of the rhesus monkey. A histochemical, light-and electron-microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367765"}
{"pmid": "4367766", "title": "Proceedings: The role of choline in maintatining the fine structure of nerve terminals in the superior cervical ganglion of cat.", "content": "Proceedings: The role of choline in maintatining the fine structure of nerve terminals in the superior cervical ganglion of cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367766"}
{"pmid": "4367768", "title": "Protein and ribonucleic acid metabolism in single-cell suspensions from Morris hepatoma 5123tc and from normal rat liver.", "content": "Protein and ribonucleic acid metabolism in single-cell suspensions from Morris hepatoma 5123tc and from normal rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367768"}
{"pmid": "4367770", "title": "Light and electron microscopic study of unfertilized egg of Ascidia malaca (Tunicata).", "content": "Light and electron microscopic study of unfertilized egg of Ascidia malaca (Tunicata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367770"}
{"pmid": "4367771", "title": "Availability of tryptophan to the brain and some hormonal and drug influences on it.", "content": "Availability of tryptophan to the brain and some hormonal and drug influences on it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367771"}
{"pmid": "4367773", "title": "Intrahepatic arterial portal communications: angiographic study.", "content": "Intrahepatic arterial portal communications: angiographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367773"}
{"pmid": "4367772", "title": "How important is the synthesis of brain 5-hydroxytryptamine in the physiological control of its central function?", "content": "How important is the synthesis of brain 5-hydroxytryptamine in the physiological control of its central function?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367772"}
{"pmid": "4367774", "title": "Macro-regenerating nodule in the cirrhotic liver. Radiologic features and differential diagnosis.", "content": "Macro-regenerating nodule in the cirrhotic liver. Radiologic features and differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367774"}
{"pmid": "4367775", "title": "Localized deformity of the gallbladder secondary to hepatic mass lesions.", "content": "Localized deformity of the gallbladder secondary to hepatic mass lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367775"}
{"pmid": "4367777", "title": "Paralytic poliomyelitis in Ontario: laboratory studies of two recent cases.", "content": "Paralytic poliomyelitis in Ontario: laboratory studies of two recent cases. Sporadic cases of paralytic poliomyelitis are being reported with increasing frequency, particularly in unvaccinated persons, in several countries in which the disease had been absent for several years following adequate initial vaccination programmes. In Ontario, two paralytic cases occurred in unvaccinated children after several disease-free years. Detailed studies of the strains of poliovirus type 1 isolated from these patients showed that they were not vaccine strains. Contact surveillance in one case showed that 21 originally unvaccinated contacts were also excreting virulent virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367777"}
{"pmid": "4367778", "title": "Assay of variola virus on microtiter plates and its application to the neutralization test.", "content": "Assay of variola virus on microtiter plates and its application to the neutralization test. It was established that microfocus assay of the variola virus in HeLa cell cultures on Microtiter plates is a suitable method for titrating the virus in numerous specimens of small volume. The variola foci were formed within 48 hours of inoculation, and the standard error for the number of foci per well did not exceed 15%, with 96 flat-bottomed wells (6 mm diameter) containing 0.1 ml per well of the culture media on a plastic plate replacing 96 Petri dishes in the standard assay procedures. Microfocus assay was successfully applied to the quantification of neutralizing antibody against variola and vaccinia viruses, with a reproducibility equal to that of the standard focus reduction method on glass Petri dishes. Applications of this technique to the assay of field specimens and to the laboratory differentiation of variola viruses are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367778"}
{"pmid": "4367779", "title": "Ecological studies on the mosquito vectors of Japanese encephalitis.", "content": "Ecological studies on the mosquito vectors of Japanese encephalitis. These studies were conducted in China (Province of Taiwan) to assess the populations of known and potential mosquito vectors of Japanese encephalitis in a typical endemic area, and to evaluate a variety of sampling techniques, some of which were new. Culex annulus was found to be the predominant vector species in the study area during the epidemic season; C. tritaeniorhynchus was never abundant, and C. fuscocephalus was rare. C. annulus and C. tritaeniorhynchus were active throughout the year, although populations were at a low level during the cool season. The results show that attention must be given to C. annulus as a possible vector where it is present in JE foci. The collection of mosquitos during the early evening hours from buffalo bait tethered outdoors was found to be the most efficient and sensitive means of monitoring vector populations throughout the year. During the JE epidemic season remarkable results were obtained with a vacuum sweep-net.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367779"}
{"pmid": "4367780", "title": "Host-feeding patterns and behaviour of 4 Culex species in an endemic area of Japanese encephalitis.", "content": "Host-feeding patterns and behaviour of 4 Culex species in an endemic area of Japanese encephalitis. Studies were made on the host-feeding patterns and behaviour of 4 Culex species in China (Province of Taiwan) to further assess their importance as vectors of Japanese encephalitis. A relatively unbiased, non-attractant technique (vacuum sweep-net) was used for collecting mosquitos resting outdoors on rural premises; blood meals from engorged specimens were identified by precipitin tests. Additional information was obtained by analysing data from related studies. Precipitin-test results indicated that C. annulus, C. tritaeniorhynchus, and C. fuscocephalus feed principally on mammals, the first species mainly on swine and the latter two largely on bovine hosts. Mosquito forage ratios suggested that the apparent preference of C. annulus for swine over bovine hosts might be a function of host density. C. annulus was found to be zoophilic, exophilic, and exophagic; however, in view of its abundance during the JE epidemic season, contact with human hosts may reach a significant level, even indoors. The other 3 species of Culex were considered to be of lesser importance as JE vectors during the 1971 epidemic season because of their host-feeding patterns and/or population densities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367780"}
{"pmid": "4367805", "title": "Association of the uterine 17beta-estradiol-receptor complex with ribonucleoprotein in vitro and in vivo.", "content": "Association of the uterine 17beta-estradiol-receptor complex with ribonucleoprotein in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367805"}
{"pmid": "4367806", "title": "Initiator methionine transfer ribonucleic acid from wheat embryo. Purification, properties, and partial nucleotide sequences.", "content": "Initiator methionine transfer ribonucleic acid from wheat embryo. Purification, properties, and partial nucleotide sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367806"}
{"pmid": "4367807", "title": "Staphylococcal transfer ribonucleic acids. II. Sequence analysis of isoaccepting glycine transfer ribonucleic acids IA and IB from Staphylococcus epidermidis Texas 26.", "content": "Staphylococcal transfer ribonucleic acids. II. Sequence analysis of isoaccepting glycine transfer ribonucleic acids IA and IB from Staphylococcus epidermidis Texas 26.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367807"}
{"pmid": "4367808", "title": "Functional groups of diphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart. Studies of cysteine residues.", "content": "Functional groups of diphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart. Studies of cysteine residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367808"}
{"pmid": "4367809", "title": "Rotational and segmental motions in the lipids of human plasma lipoproteins.", "content": "Rotational and segmental motions in the lipids of human plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367809"}
{"pmid": "4367810", "title": "Structure and methylation of coenzyme M(HSCH2CH2SO3).", "content": "Structure and methylation of coenzyme M(HSCH2CH2SO3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367810"}
{"pmid": "4367811", "title": "Soluble cytochrome b-c1 complex and the reconstitution of succinate-cytochrome c reductase.", "content": "Soluble cytochrome b-c1 complex and the reconstitution of succinate-cytochrome c reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367811"}
{"pmid": "4367812", "title": "Physical and kinetic studies of arginyl transfer ribonucleic acid ligase of Neurospora. A sequential ordered mechanism.", "content": "Physical and kinetic studies of arginyl transfer ribonucleic acid ligase of Neurospora. A sequential ordered mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367812"}
{"pmid": "4367813", "title": "Cyclic 3':5'-nucleotide phosphodiesterase. Purification, characterization, and active form of the protein activator from bovine brain.", "content": "Cyclic 3':5'-nucleotide phosphodiesterase. Purification, characterization, and active form of the protein activator from bovine brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367813"}
{"pmid": "4367814", "title": "Isolation and alignment of the tryptic peptides of alanine apolipoprotein, an apolipoprotein from human plasma very low density lipoproteins.", "content": "Isolation and alignment of the tryptic peptides of alanine apolipoprotein, an apolipoprotein from human plasma very low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367814"}
{"pmid": "4367815", "title": "Phosphorylation of a cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine cardiac muscle.", "content": "Phosphorylation of a cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine cardiac muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367815"}
{"pmid": "4367816", "title": "Aflatoxin hepatic carcinogenesis (sequential study in albino rats).", "content": "Aflatoxin hepatic carcinogenesis (sequential study in albino rats).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367816"}
{"pmid": "4367817", "title": "Microbial opportunism in clinical medicine.", "content": "Microbial opportunism in clinical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367817"}
{"pmid": "4367820", "title": "The metabolism of vitamin D; recent developments and their clinical relevance.", "content": "The metabolism of vitamin D; recent developments and their clinical relevance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367820"}
{"pmid": "4367821", "title": "Idiopathic thrombocytopenic purpura.", "content": "Idiopathic thrombocytopenic purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367821"}
{"pmid": "4367827", "title": "Etiology and laboratory diagnosis of infectious mononucleosis: II. Cytomegalovirus (CMV) mononucleosis.", "content": "Etiology and laboratory diagnosis of infectious mononucleosis: II. Cytomegalovirus (CMV) mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367827"}
{"pmid": "4367826", "title": "Etiology and laboratory diagnosis of infectious mononucleosis: I. Epstein-Barr virus (EBV) mononucleosis.", "content": "Etiology and laboratory diagnosis of infectious mononucleosis: I. Epstein-Barr virus (EBV) mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367826"}
{"pmid": "4367825", "title": "Classification and treatment of seizure disorders in children.", "content": "Classification and treatment of seizure disorders in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367825"}
{"pmid": "4367828", "title": "Foreign body granuloma of synovium following intra-articular injection.", "content": "Foreign body granuloma of synovium following intra-articular injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367828"}
{"pmid": "4367829", "title": "Gout and pseudogout established by polarized light microscopy of synovial fluid. Methods and two case reports.", "content": "Gout and pseudogout established by polarized light microscopy of synovial fluid. Methods and two case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367829"}
{"pmid": "4367830", "title": "Histogenesis of prostatic carcinomas.", "content": "Histogenesis of prostatic carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367830"}
{"pmid": "4367831", "title": "Cyclic changes in the uterine phosphatases during breeding and non-breeding seasons of Hemiechinus auritus collaris Gray, the Indian long-cared hedgehog.", "content": "Cyclic changes in the uterine phosphatases during breeding and non-breeding seasons of Hemiechinus auritus collaris Gray, the Indian long-cared hedgehog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367831"}
{"pmid": "4367832", "title": "Virus content of sewage in different seasons in Hungary.", "content": "Virus content of sewage in different seasons in Hungary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367832"}
{"pmid": "4367833", "title": "Intraspecific variation in Plasmodium falciparum.", "content": "Intraspecific variation in Plasmodium falciparum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367833"}
{"pmid": "4367834", "title": "Malaria antibody levels in patients with Burkitt's lymphoma.", "content": "Malaria antibody levels in patients with Burkitt's lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367834"}
{"pmid": "4367835", "title": "The interaction between Entamoeba histolytica and Trichuris muris infections in mice.", "content": "The interaction between Entamoeba histolytica and Trichuris muris infections in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367835"}
{"pmid": "4367836", "title": "Susceptibility of Schistosoma mansoni from Liberia and Puerto Rico to antischistosomal drugs.", "content": "Susceptibility of Schistosoma mansoni from Liberia and Puerto Rico to antischistosomal drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367836"}
{"pmid": "4367838", "title": "Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. I. Vegetative growth of mycelium and arthrospore formation in submerged and aerated cultures.", "content": "Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. I. Vegetative growth of mycelium and arthrospore formation in submerged and aerated cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367838"}
{"pmid": "4367839", "title": "The presence of unusual microtubular structures in senescent cells of Chlamydomonas dysosmos.", "content": "The presence of unusual microtubular structures in senescent cells of Chlamydomonas dysosmos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367839"}
{"pmid": "4367842", "title": "Treatment of Wilm's tumor. Diagnosis and surgical treatment.", "content": "Treatment of Wilm's tumor. Diagnosis and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367842"}
{"pmid": "4367840", "title": "Inorganic polyphosphates and enzymes of polyphosphate metabolism in the cellular slime mold Dictyostelium discoideum.", "content": "Inorganic polyphosphates and enzymes of polyphosphate metabolism in the cellular slime mold Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367840"}
{"pmid": "4367841", "title": "Cyanide-insensitive respiration in Moniliella tomentosa and the effect of drugs on respiration and polyol biosynthesis.", "content": "Cyanide-insensitive respiration in Moniliella tomentosa and the effect of drugs on respiration and polyol biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367841"}
{"pmid": "4367843", "title": "Treatment of Wilm's tumor. Radiotherapy.", "content": "Treatment of Wilm's tumor. Radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367843"}
{"pmid": "4367844", "title": "Treatment of Wilm's tumor. Chemotherapy.", "content": "Treatment of Wilm's tumor. Chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367844"}
{"pmid": "4367845", "title": "Cyclic nucleotide binding and protein kinase in the central nervous system of Galleria mellonella (L.).", "content": "Cyclic nucleotide binding and protein kinase in the central nervous system of Galleria mellonella (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367845"}
{"pmid": "4367846", "title": "Measured and calculated NAD+-NADH ratios in human erythrocytes.", "content": "Measured and calculated NAD+-NADH ratios in human erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367846"}
{"pmid": "4367849", "title": "Catabolite repression of L-arabinose isomerase in Escherichia coli induced by ultraviolet irradiation.", "content": "Catabolite repression of L-arabinose isomerase in Escherichia coli induced by ultraviolet irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367849"}
{"pmid": "4367847", "title": "Turnover of hepatic mitochondrial ornithine aminotransferase and cytochrome oxidase using (14C)carbonate as tracer.", "content": "Turnover of hepatic mitochondrial ornithine aminotransferase and cytochrome oxidase using (14C)carbonate as tracer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367847"}
{"pmid": "4367848", "title": "Hormonal regulation of collagen degradation in the uterus: inhibition of collagenase expression by progesterone and cyclic AMP.", "content": "Hormonal regulation of collagen degradation in the uterus: inhibition of collagenase expression by progesterone and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367848"}
{"pmid": "4367850", "title": "Regulation of growth in vitro. I. Control of ornithine decarboxylase levels in untransformed and transformed mouse fibroblasts by serum.", "content": "Regulation of growth in vitro. I. Control of ornithine decarboxylase levels in untransformed and transformed mouse fibroblasts by serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367850"}
{"pmid": "4367851", "title": "Structural changes in rat liver endoplasmic reticulum following triiodothyronine administration.", "content": "Structural changes in rat liver endoplasmic reticulum following triiodothyronine administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367851"}
{"pmid": "4367855", "title": "Fluorescence and electron microscopical study of aminergic nuclei in the brain of Bufo poweri.", "content": "Fluorescence and electron microscopical study of aminergic nuclei in the brain of Bufo poweri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367855"}
{"pmid": "4367856", "title": "Origin and fate of the multivesicular bodies in PHA stimulated lymphocytes.", "content": "Origin and fate of the multivesicular bodies in PHA stimulated lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367856"}
{"pmid": "4367857", "title": "A quantitative study of the ultrastructural changes in the hypothalamo-neurohypophysial system during and after experimentally induced hypersecretion.", "content": "A quantitative study of the ultrastructural changes in the hypothalamo-neurohypophysial system during and after experimentally induced hypersecretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367857"}
{"pmid": "4367858", "title": "Structure and ultrastructure of the central nervous system of the polychaete Nephtys, with special reference to photoreceptor elements.", "content": "Structure and ultrastructure of the central nervous system of the polychaete Nephtys, with special reference to photoreceptor elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367858"}
{"pmid": "4367859", "title": "Cholinesterase in the posterior pituitary. Increased number of reactive pituicytes in the dehydrated rat.", "content": "Cholinesterase in the posterior pituitary. Increased number of reactive pituicytes in the dehydrated rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367859"}
{"pmid": "4367860", "title": "Lipidosis-like alterations in hypothalamic neurosecretory cells of rats treated with chlorphentermine or iprindole.", "content": "Lipidosis-like alterations in hypothalamic neurosecretory cells of rats treated with chlorphentermine or iprindole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367860"}
{"pmid": "4367861", "title": "Nerve endings in the arteria centralis retinae.", "content": "Nerve endings in the arteria centralis retinae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367861"}
{"pmid": "4367862", "title": "Investigations on the fine structure of Purkinje fibres in the atrium of the avian heart.", "content": "Investigations on the fine structure of Purkinje fibres in the atrium of the avian heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367862"}
{"pmid": "4367863", "title": "Ultrastructure of neurohemal organs (paraganglionic plates) of Trogulus nepaeformis (Scopoli) (Opiliones, Trogulidae) and release of neurosecretory material.", "content": "Ultrastructure of neurohemal organs (paraganglionic plates) of Trogulus nepaeformis (Scopoli) (Opiliones, Trogulidae) and release of neurosecretory material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367863"}
{"pmid": "4367864", "title": "Ivestigations on adrenocortical mitochondria turnover. I. Effect of chronic treatment with ACTH on the size and number of rat zona fasciculata mitochondria.", "content": "Ivestigations on adrenocortical mitochondria turnover. I. Effect of chronic treatment with ACTH on the size and number of rat zona fasciculata mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367864"}
{"pmid": "4367865", "title": "Ultrastructure of mucosal mast cells in normal and compound 48-80-treated rats.", "content": "Ultrastructure of mucosal mast cells in normal and compound 48-80-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367865"}
{"pmid": "4367868", "title": "A modified thymol turbidity test in hyperglobulinaemia.", "content": "A modified thymol turbidity test in hyperglobulinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367868"}
{"pmid": "4367867", "title": "Anti-DNA virus activity of the 5'-nucleotide and 3',5'-cyclic nucleotide of 9-beta-D-arabinofuranosyladenine.", "content": "Anti-DNA virus activity of the 5'-nucleotide and 3',5'-cyclic nucleotide of 9-beta-D-arabinofuranosyladenine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367867"}
{"pmid": "4367869", "title": "The use of density gradient centrifugation for the separation of serum lipoproteins.", "content": "The use of density gradient centrifugation for the separation of serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367869"}
{"pmid": "4367870", "title": "The use of nitroblue tetrazolium prestaining of serum lipoproteins on polyacrylamide disc electrophoresis.", "content": "The use of nitroblue tetrazolium prestaining of serum lipoproteins on polyacrylamide disc electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367870"}
{"pmid": "4367871", "title": "Hepatic hexokinase isozyme in liver diseases.", "content": "Hepatic hexokinase isozyme in liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367871"}
{"pmid": "4367873", "title": "Possible association between an abnormal low density lipoprotein and nephropathy in lecithin: cholesterol acyltransferase deficiency.", "content": "Possible association between an abnormal low density lipoprotein and nephropathy in lecithin: cholesterol acyltransferase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367873"}
{"pmid": "4367872", "title": "Effect of Al-chlorophenoxyisobutyrate (Alufibrate) on pyruvate metabolism and on the fate of very low density lipoprotein lipids in hyperlipidemic patients.", "content": "Effect of Al-chlorophenoxyisobutyrate (Alufibrate) on pyruvate metabolism and on the fate of very low density lipoprotein lipids in hyperlipidemic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367872"}
{"pmid": "4367874", "title": "A modified radiochemical assay for serum free fatty acid determination.", "content": "A modified radiochemical assay for serum free fatty acid determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367874"}
{"pmid": "4367875", "title": "Effect of lipoic acid on tissue respiration in rabbits with experimental atherosclerosis.", "content": "Effect of lipoic acid on tissue respiration in rabbits with experimental atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367875"}
{"pmid": "4367878", "title": "Comparison of the frequencies of spontaneous and chemically-induced 5-bromodeoxyuridine-resistance mutations in wild-type and revertant BHK-21-13 cells.", "content": "Comparison of the frequencies of spontaneous and chemically-induced 5-bromodeoxyuridine-resistance mutations in wild-type and revertant BHK-21-13 cells. 5-bromodeoxyuridine resistance mutations induced by mutagenesis were studied. The average expression time for induced mutations varied with the concentration of the mutagen ethyl methanesulfonate (EMS). However, a constant number of two generation times was necessary for half maximal expression of induced mutations. Also, induced mutation rates were compared under optimal expression conditions for bromodeoxyuridine, fluorodeoxyuridine and azaguanine resistance markers. Ten independent bromodeoxy-uridine-resistant clones were tested for reversion. Two clones reverted-one spontaneously and the other after mutagenesis. The spontaneous rate of mutation to bromodeoxyuridine resistance, estimated by the fluctuation test, was high in revertant clones (4 x 10(-6) / cell / generation) and low in the wild-type cells (< 3.5 x 10(-8) / cell / generation). A comparison of induced mutation frequencies at variable EMS concentrations showed a single-hit curve for revertant clones and a multihit curve for the wild-type cells. Thymidine kinase activities of resistant clones were usually less than 2% of that of the wild-type clone. Inducibility, thermal stability and intracellular localization of the thymidine kinases of the wild-type cells and of a revertant clone were identical. A low, but significant (P < 0.10), Km discrepancy was observed between enzyme extracts of these lines. The genetic implications of these results are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367878"}
{"pmid": "4367877", "title": "Mutants of yeast defective in iso-1-cytochrome c.", "content": "Mutants of yeast defective in iso-1-cytochrome c. A medium containing chlorolactate has been devised to enrich for mutants that are unable to utilize lactate for growth, and therefore that may be defective in cytochrome c. Complementation tests of 6,520 chlorolactate-resistant mutants that were obtained spontaneously or induced with UV, ICR-170, or nitrosoimidazolidone resulted in the identification of 195 mutations at the cyc1 locus, which controls the primary structure of iso-1-cytochrome c. These 195 mutants, with 16 cyc1 mutants previously isolated, were examined for total cytochrome c by spectroscopic methods, growth on lactate medium, suppressibility by defined nonsense suppressors, mutational sites by x-ray-induced recombination, ability to revert, and in 86 cases, whether intragenic revertants contain altered iso-1-cytochrome c. Except for the deletion mutant cyc1-1, all of the mutants appeared to contain single-site mutations that could be assigned to at least 35 different sites within the gene. The cyc1 mutants either completely lacked iso-1-cytochrome c or contained iso-1- cytochromes c that were completely or partially nonfunctional. In spite of the fact that the cyc1 mutants obtained by the chlorolactate procedure were selected on the basis of defective function, 68% appeared to completely lack iso-1-cytochrome c. The remaining cyc1 mutants contained below normal amounts of iso-1-cytochromes c. Studies at several incubation temperatures indicated that these nonfunctional iso-1-cytochromes c were thermolabile. It is suggested that the predominant means for abolishing iso-1-cytochrome c by mutations are either through a complete loss, such as produced by chain terminating codons, or impairments through drastic changes of tertiary structure which lead to instability and thermolability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367877"}
{"pmid": "4367879", "title": "Localization of 3', 5'-cyclic nucleotide phosphodiesterase activity in isolated thyroid cells and intact thyroid tissue.", "content": "Localization of 3', 5'-cyclic nucleotide phosphodiesterase activity in isolated thyroid cells and intact thyroid tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367879"}
{"pmid": "4367881", "title": "An affinity column method for partial purification of cytochrome P-450 from phenobarbital-induced rabbit liver microsomes.", "content": "An affinity column method for partial purification of cytochrome P-450 from phenobarbital-induced rabbit liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367881"}
{"pmid": "4367883", "title": "Reactivity of peptide imino groups in proteins with tert-butyl hypochlorite in relation to secondary structure.", "content": "Reactivity of peptide imino groups in proteins with tert-butyl hypochlorite in relation to secondary structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367883"}
{"pmid": "4367882", "title": "Nuclear phosphoprotein kinases from rat liver.", "content": "Nuclear phosphoprotein kinases from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367882"}
{"pmid": "4367884", "title": "Phosphodiesterase-phosphomonoesterases from Fusarium moniliforme. IV. Kinetic studies.", "content": "Phosphodiesterase-phosphomonoesterases from Fusarium moniliforme. IV. Kinetic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367884"}
{"pmid": "4367885", "title": "N-acyl specificity of Taka-N-acetyl-beta-d-glucosaminidase. IV. Essential requirement of the 2-acetamide-carbonyl group for the enzymatic hydrolysis.", "content": "N-acyl specificity of Taka-N-acetyl-beta-d-glucosaminidase. IV. Essential requirement of the 2-acetamide-carbonyl group for the enzymatic hydrolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367885"}
{"pmid": "4367886", "title": "Malignant fibrous histiocytoma and osteosarcoma in association with bone infarcts; report of four cases, two in caisson workers.", "content": "Malignant fibrous histiocytoma and osteosarcoma in association with bone infarcts; report of four cases, two in caisson workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367886"}
{"pmid": "4367887", "title": "Effects of colchicine and vinblastine on the cellular action of vasopressin in mammalian kidney. A possible role of microtubules.", "content": "Effects of colchicine and vinblastine on the cellular action of vasopressin in mammalian kidney. A possible role of microtubules. To evaluate the possible role of microtubules in the cellular action of vasopressin on the mammalian kidney, the effects of microtubule-disrupting agents were studied in vivo and in vitro. In vivo studies were done in rats in mild to moderate water diuresis induced by drinking 5% glucose. Microtubule-disrupting alkaloids, colchicine (0.1 mg/day) or vinblastine (0.08 mg/day), given intraperitoneally, did not change water and solute excretion itself, but blocked or markedly inhibited the antidiuretic response (increase in urine osmolality and decrease in urine flow) to exogenous vasopressin. Total solute excretion was unaffected by these two alkaloids and there were no substantial changes in excretion of sodium, potassium, or creatinine. Lumicolchicine, a derivative of colchicine that does not interact with microtubules, did not alter the antidiuretic response to exogenous vasopressin. Activities of adenylate cyclase in the renal medullary plasma membrane, and cyclic AMP phosphodiesterase and protein kinase in renal medullary cytosol, were not influenced by 10(-5)-10(-4) M colchicine or vinblastine in vitro. Studies on the subcellular distribution of microtubular protein (assessed as [(3)H]colchicine-binding protein) in renal medulla shows that this protein is contained predominantly in the cytosol. Particulate fractions, including plasma membrane, contain only a minute amount (less than 6%) of the colchicine-binding activity. The results suggest that the integrity of cytoplasmic microtubules in cells of the distal nephron is required for the antidiuretic action of vasopressin, probably in the sites distal to cyclic AMP generation in the mammalian kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367887"}
{"pmid": "4367888", "title": "Utilization of alpha-keto and alpha-hydroxy analogues of valine by the growing rat.", "content": "Utilization of alpha-keto and alpha-hydroxy analogues of valine by the growing rat. When 70-80-g male albino rats eat a diet furnishing daily requirement of valine for optimal growth (70 mumol/g) and all other nutrients (\"complete diet\"), they gain weight at an average rate of 3.0 g/100 g body wt/day. When valine is removed, they lose weight at an average 2.1 g/100 g body wt/day. The growth retardation is improved or corrected by adding valine to the diet, daily weight gain being proportional to dietary valine content over a range of 0-70 mumol/g. Addition of alpha-ketoisovaleric acid instead of valine to the valine-free diet also improves or corrects the growth failure. Percent efficiency of alpha-ketoisovaleric acid as a substitute for valine was calculated as: 100 x (micromole valine per gram diet required to produce specified growth response)/(micromole alpha-ketoisovaleric acid per gram diet required to produce the same response). Efficiency of the substitution is inversely related to dietary content of the keto analogue, being 80% when diet contains 17.5 mumol/g (molar equivalent of (1/4) the daily requirement of valine), and 37% when diet provides 140 mumol/g (molar equivalent of twice the daily requirement of valine).alpha-Hydroxyisovaleric acid also substitutes for valine. Efficiency of the substitution at the single ration tested, 70 mumol/g diet, is 45%, similar to that for the keto analogue under the same conditions. When [1-(14)C]alpha-ketoisovaleric acid is injected intravenously, 30-80% of the administered radioactivity is exhaled as (14)CO(2) within 24 h. This finding suggests that inefficiency of alpha-ketoisovaleric acid as a substitute for valine results in part from degradation of the keto acid to isobutyric acid by branched chain dehydrogenase-decarboxylase. Oral administration of neomycin, polymyxin, and bacitracin reduces efficiency of alpha-ketoisovaleric acid as a substitute for valine by (1/4)-(1/2). This effect suggests that transamination of the keto acid may be performed in part by gastrointestinal microbes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367888"}
{"pmid": "4367889", "title": "The turnover of cholesterol in human atherosclerotic arteries.", "content": "The turnover of cholesterol in human atherosclerotic arteries. The equilibration of cholesterol between plasma and atherosclerotic arteries was studied in 13 patients with obstructive atherosclerosis 2-96 days after the intravenous and/or oral administration of isotopic cholesterol. Arterial specimens were obtained in 12 patients during surgery for arterial reconstruction and in a 13th patient at autopsy. Equilibration was calculated as the specific radioactivity of cholesterol in the arterial tissue relative to that in the plasma (percent).In specimens obtained 2-4 days after pulse labeling, the specific activity of cholesterol in atheroma ranged from 0.3 to 4.5% of that in the plasma. By 17-27 days, the relative specific activity ranged from 6 to 20% in different arteries. In contrast, cholesterol of skeletal muscle had a relative specific activity of 96% by 22 days. By 61-96 days, atheroma cholesterol in the abdominal aorta, common iliac, and femoral arteries had equilibrated to 55, 30, and 26%, respectively. In the patient who died at 96 days, the cholesterol in the coronary arteries had a mean equilibration of 66%, similar to the values for the abdominal (66%) and thoracic (57%) aortas. The route of administration of the isotope did not influence the equilibration. Within the atheromatous plaque, the superficial layers equilibrated better than the deeper layers (75% vs. 22%). The free cholesterol in the atheroma equilibrated to a significantly higher extent than did esterified cholesterol (59% vs. 38%). There was a fourfold higher specific activity of cholesterol in the media than in the corresponding intima (916 vs. 230 dpm/mg). The estimated minimal influx rates of plasma cholesterol into the atheromatous intima ranged from 0.065 to 0.274 mg of cholesterol/g dry tissue per day for different arteries. The approximated turnover times of atheroma cholesterol ranged from 442 days for the abdominal aorta and the coronary arteries to 580 days for the common iliac and 821 and 934 days, respectively, for the femoral and the carotid arteries. These data indicate a definite, though slow, exchange of cholesterol between the plasma and severely atherosclerotic human arteries. Within the atheroma, there are multiple pools of cholesterol, each turning over differently and more slowly than the cholesterol of most other tissues, such as the skeletal muscle. The estimates of influx rate and turnover time of atheroma cholesterol suggest the possibility that this cholesterol is mobilizable, an indication of potential regression of atheromatous lesions in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367889"}
{"pmid": "4367892", "title": "Studies on locust neuromuscular physiology in relation to glutamic acid.", "content": "Studies on locust neuromuscular physiology in relation to glutamic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367892"}
{"pmid": "4367890", "title": "Release of prostaglandin by mitogen- and antigen-stimulated leukocytes in culture.", "content": "Release of prostaglandin by mitogen- and antigen-stimulated leukocytes in culture. The prostaglandin (PG) content of mitogen- and antigen-stimulated leukocyte cultures was examined by a radioimmunoassay procedure empolying an antiserum reactive with PGB(1) and PGB(2), the alkaline dehydration products of PGE and PGA. At 48 h, mitogen-activated mouse spleen cell cultures showed 2-10-fold increases in the PGE, but not in the PGA, component of immunoreactive PG (iPG) fractionated by silicic acid column chromatography. Increases in iPG were detectable by h 16 in spleen cell cultures incubated with staphylococcal enterotoxin B. Since iPG levels rose only in the culture supernates and not in cells exposed to mitogens for 48 h, increases reflected extracellular release of PG. The validity of the radioimmunoassay determinations of PGE in spleen cell cultures was supported by the results of concomitant assessment of the PGE(2) content of basal and enterotoxin-stimulated cultures by gas chromatography/mass spectrometry. By the latter method, the PGE(2) content was three-fold higher in enterotoxin-activated, compared to basal, cultures at 48 h. Aspirin effectively suppressed increases in both iPG and PGE(2). In spleen cell cultures prepared from mice previously inoculated with an attenuated strain of yellow fever virus in vivo and then incubated with this virus in vitro, iPG levels increased twofold over basal at 48 h. By contrast, iPG content of spleen cell cultures prepared from saline-inoculated mice was not appreciably altered by exposure to the virus in vitro. The enhancement of iPG release from cultured spleen cells by mitogens did not correlate with an ability of these agents to increase cellular cyclic AMP (cAMP) levels. Moreover, epinephrine and cholera toxin markedly increased spleen cell cAMP content but had no demonstrable effect on basal iPG levels, suggesting iPG release from these cells was not mediated by cAMP. Incubation with mitogens also enhanced the iPG content of 72-cultures of human peripheral leukocytes and of human lymphocytes isolated by nylon chromatography. However, the iPG of cultures of human lymphocytes purified by glass bead chromatography and of mouse thymocytes was not appreciably altered when these cells were cultured with mitogens, even though DNA synthesis in both instances was markedly increased. Accordingly, iPG release was not an invariable concomitant of increased DNA synthesis in lymphoid cell cultures. In summary, the results demonstrate that mitogen and antigen stimulation of leukocytes in culture may be accompanied by enhanced release of PGE. The mechanisms mediating this phenomenon and its biologic significance remain to be delineated, but participation of PGE in immunologically induced inflammatory responses seems possible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367890"}
{"pmid": "4367893", "title": "L-glutamate in arthropod blood plasma: physiological implications.", "content": "L-glutamate in arthropod blood plasma: physiological implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367893"}
{"pmid": "4367891", "title": "The hypercalciurias. Causes, parathyroid functions, and diagnostic criteria.", "content": "The hypercalciurias. Causes, parathyroid functions, and diagnostic criteria. The causes for the hypercalciuria and diagnostic criteria for the various forms of hypercalciuria were sought in 56 patients with hypercalcemia or nephrolithiasis (Ca stones), by a careful assessment of parathyroid function and calcium metabolism. A study protocol for the evaluation of hypercalciuria, based on a constant liquid synthetic diet, was developed. In 26 cases of primary hyperparathyroidism, characteristic features were: hypercalcemia, high urinary cyclic AMP (cAMP, 8.58+/-3.63 SD mumol/g creatinine; normal, 4.02+/-0.70 mumol/g creatinine), high immunoreactive serum parathyroid hormone (PTH), hypercalciuria, the urinary Ca exceeding absorbed Ca from intestinal tract (Ca(A)), high fasting urinary Ca (0.2 mg/mg creatinine or greater), and low bone density by (125)I photon absorption. The results suggest that hypercalciuria is partly secondary to an excessive skeletal resorption (resorptive hypercalciuria). The 22 cases with renal stones had normocalcemia, hypercalciuria, intestinal hyperabsorption of calcium, normal or low serum PTH and urinary cAMP, normal fasting urinary Ca, and normal bone density. Since their Ca(A) exceeded urinary Ca, the hypercalciuria probably resulted from an intestinal hyperabsorption of Ca (absorptive hypercalciuria). The primacy of intestinal Ca hyperabsorption was confirmed by responses to Ca load and deprivation under a metabolic dietary regimen. During a Ca load of 1,700 mg/day, there was an exaggerated increase in the renal excretion of Ca and a suppression of cAMP excretion. The urinary Ca of 453+/-154 SD mg/day was significantly higher than the control group's 211+/-42 mg/day. The urinary cAMP of 2.26+/-0.56 mumol/g creatinine was significantly lower than in the control group. In contrast, when the intestinal absorption of calcium was limited by cellulose phosphate, the hypercalciuria was corrected and the suppressed renal excretion of cAMP returned towards normal. Two cases with renal stones had normocalcemia, hypercalciuria, and high urinary cAMP or serum PTH. Since Ca(A) was less than urinary Ca, the hypercalciuria may have been secondary to an impaired renal tubular reabsorption of Ca (renal hypercalciuria). Six cases with renal stones had normal values of serum Ca, urinary Ca, urinary cAMP, and serum PTH (normocalciuric nephrolithiasis). Their Ca(A) exceeded urinary Ca, and fasting urinary Ca and bone density were normal. The results support the proposed mechanisms for the hypercalciuria and provide reliable diagnostic criteria for the various forms of hypercalciuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367891"}
{"pmid": "4367894", "title": "Saturday night retinopathy.", "content": "Saturday night retinopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367894"}
{"pmid": "4367895", "title": "Paradoxical effects of d-amphetamine on behavioral thermoregulation: possible mediation by brain dopamine.", "content": "Paradoxical effects of d-amphetamine on behavioral thermoregulation: possible mediation by brain dopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367895"}
{"pmid": "4367896", "title": "Effects of intracellularly applied cyclic 3',5'-adenosine monophosphate and dibutyryl cyclic 3',5'-adenosine monophosphate on the electrical activity of sinoatrial nodal cells of the rabbit.", "content": "Effects of intracellularly applied cyclic 3',5'-adenosine monophosphate and dibutyryl cyclic 3',5'-adenosine monophosphate on the electrical activity of sinoatrial nodal cells of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367896"}
{"pmid": "4367898", "title": "Inhibition of angiotensin-induced adrenal catecholamine release by 8-substituted analogs of angiotensin II.", "content": "Inhibition of angiotensin-induced adrenal catecholamine release by 8-substituted analogs of angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367898"}
{"pmid": "4367897", "title": "Influence of various substances which induce and inhibit aggregation on the uptake of deoxyglucose by human blood platelets.", "content": "Influence of various substances which induce and inhibit aggregation on the uptake of deoxyglucose by human blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367897"}
{"pmid": "4367899", "title": "Reliability of the RNA-DNA filter hybridization for the detection of oncornavirus-specific DNA sequences.", "content": "Reliability of the RNA-DNA filter hybridization for the detection of oncornavirus-specific DNA sequences. Denatured DNA from leukemic myeloblasts or uninfected chicken embryos, immobilized on nitrocellulose filters, was hybridized to a vast excess of [(3)H]70S RNA from purified avian myeloblastosis virus. The viral RNA was eluted from the RNA-DNA hybrids, purified, and then rehybridized in solution to an excess of either leukemic or normal chicken embryonic DNA. This study revealed that all the slow and the fast hybridizing viral RNA sequences detectable by liquid hybridization in DNA excess had hybridized to the filter bound DNA. Both techniques also gave similar values for the number of 28S ribosomal RNA genes contained in a chicken cell genome: 210 by the liquid hybridization procedure and 218 by the filter hybridization technique. Therefore, filter hybridization can accurately detect DNA sequences present in relatively few numbers in the genome of higher organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367899"}
{"pmid": "4367902", "title": "Cleavage of mengovirus polyproteins in vivo.", "content": "Cleavage of mengovirus polyproteins in vivo. The synthesis of mengovirus-specific proteins in vivo was studied by labeling the viral proteins with radioactive amino acids under conditions in which host protein synthesis was almost completely inhibited. Pulse-chase experiments enabled the kinetic analysis of the cleavages of certain viral protein precursors and the formation of others. The pattern of cleavages of mengovirus precursor polypeptides is similar to that of encephalomyocarditis virus. The major difference between the two viruses seems to be in the molar concentration in which the various primary products are produced. The molar ratio of the A protein, which is the precursor of the capsid proteins, to that of the primary products F and C, is approximately 1.5 to 2.0: 1: 1. Possible explanations for the unequal appearance of the structural and nonstructural proteins are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367902"}
{"pmid": "4367900", "title": "Selection of revertants of Kirsten sarcoma virus transformed nonproducer BALB-3T3 cells.", "content": "Selection of revertants of Kirsten sarcoma virus transformed nonproducer BALB-3T3 cells. Revertants of Kirsten sarcoma virus transformed nonproducer BALB/3T3 cells (KA31 cells) were isolated after exposing the transformed cells to 5-fluorodeoxyuridine at high cell density, or when suspended in methylcellulose. Revertants were also isolated by treating KA31 cells with the lectin, concanavalin A, which is manyfold more toxic to transformed cells than for normal cells. The revertants resemble BALB/3T3 cells in their morphology and growth characteristics in that they have a low saturation density, fail to grow in 1% calf serum or when suspended in methylcellulose, and cease to synthesize DNA after reaching their saturation density. Infection by murine leukemia virus rescues Kirsten sarcoma virus from only the concanavalin-A-selected variants, though all the revertants are susceptible to infection by leukemia virus. The concanavalin A revertants also become transformed after infection with murine leukemia virus. All the revertants can be transformed by Kirsten sarcoma virus but not by simian virus 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367900"}
{"pmid": "4367903", "title": "Sialoglycoprotein of vesicular stomatitis virus: role of the neuraminic acid in infection.", "content": "Sialoglycoprotein of vesicular stomatitis virus: role of the neuraminic acid in infection. Neuraminidase free of proteolytic activity substantially reduced the infectivity of vesicular stomatitis (VS) virus but less effectively than trypsin. The only sugar residue hydrolyzed by neuraminidase was N-acetyl neuraminic acid, approximately 89% of which was liberated from virion glycoprotein and the rest from virion glycolipid. Desialylation of virion glycoprotein but not of glycolipid resulted in progressive loss of infectivity. Sialyl transferase prepared and partially purified from BHK-21 cells catalyzed resialylation by CMP-[(14)C]sialic acid of the glycoprotein of neuraminidase-treated VS virions and supersialylation of unhydrolyzed VS viral glycoprotein. Resialylation of desialylated VS virions resulted in substantial (26-fold) restoration of their infectivity. We conclude that terminal neuraminic acids of VS viral sialoglycoprotein play an important role in initiation of infection with this virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367903"}
{"pmid": "4367901", "title": "Characterization of late polyoma mRNA.", "content": "Characterization of late polyoma mRNA. Polyoma-infected mouse kidney cell cultures were labeled with [(3)H]uridine for 3 h late in the lytic cycle (26 to 29 h after infection) and RNA was extracted from cytoplasm and nuclei and from isolated polyribosomes. Sedimentation velocity analysis in sucrose gradients showed that polyoma-specific \"giant\" and 26S RNAs are present exclusively in the nucleus. RNA associated with cytoplasmic polyribosomes was analyzed by sedimentation in aqueous sucrose density gradients and dimethylsulfoxide sucrose gradients, as well as by polyacrylamide gel electrophoresis. Polyoma-specific RNA in polyribosomes consists of at least two classes, with sedimentation coefficients of 16 (major fraction) and 19S (minor fraction) in aqueous sucrose gradients and 15 and 17S, respectively, in dimethylsulfoxide gradients. Estimates based on dimethylsulfoxide gradient and analysis suggest a molecular weight of approximately 500,000 for 16S RNA and 700,000 for 19S RNA. These polyoma RNAs seem to undergo reversible conformational changes under the different conditions of analysis. We cannot exclude the possibility that they contain more than one molecular species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367901"}
{"pmid": "4367904", "title": "Characterization of the large picornaviral polypeptides produced in the presence of zinc ion.", "content": "Characterization of the large picornaviral polypeptides produced in the presence of zinc ion. Zinc ion inhibits the posttranslational cleavages of human rhinovirus-1A, encephalomyocarditis virus, and poliovirus polypeptides. Each virus displayed a different susceptibility to zinc. However, in each case the cleavages of the capsid precursor and the cleavages analogous to the C --> D --> E conversion in encephalomyocarditis virus were most sensitive to zinc. Higher concentrations of zinc resulted in the buildup of even larger precursor polypeptides of a size between 106,000 and 214,000 daltons. The sizes of these polypeptides and the relative position of their gene loci on the viral RNA were determined. These data were used to place these polypeptides in the over-all scheme of viral protein processing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367904"}
{"pmid": "4367906", "title": "Rhabdovirus replication in enucleated host cells.", "content": "Rhabdovirus replication in enucleated host cells. Infection of enucleated TC-7 monkey cells with rabies virus resulted in the synthesis of virus-directed RNA and the production of rabies antigens but not of infectious virus. The yield of infectious vesicular stomatitis virus from enucleated TC-7 cells, on the other hand, was almost as high as that from intact cells. Inhibition of the mitochondrial functions of enucleated cells by treatment with ethidium bromide did not influence the development of rabies antigens or the production of infectious vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367906"}
{"pmid": "4367905", "title": "Transcriptional regulation of T4 bacteriophage-specific enzymes synthesized in vitro.", "content": "Transcriptional regulation of T4 bacteriophage-specific enzymes synthesized in vitro. In contrast to dihydrofolate reductase and four other phage-specific enzymes, the initiation of deoxynucleotide kinase is essentially prevented if rifampin is added to a culture of Escherichia coli B cells within 1.5 min after infection with T4. Deoxynucleotide kinase thus belongs to a group of so-called delayed-early enzymes that is not initiated from an immediate-early promoter site. We prepared crude extracts from infected cells in a manner designed to maintain the integrity of the complexes of native, endogenous T4 DNA with bacterial structural and enzymatic units concerned with RNA synthesis. The initiation of the synthesis of the mRNA for dihydrofolate reductase, an example of an immediate-early enzyme, and deoxynucleotide kinase, a special type of delayed-early enzyme, was studied with these extracts prepared from cells infected in the absence or presence of chloramphenicol. Initiation of transcription of the dihydrofolate reductase gene is immediate when programmed by extracts made either from cells treated with chloramphenicol prior to infection (CM extracts) or from cells 3 min into the normal infection cycle (3-min extracts). However, initiation of transcription of the deoxynucleotide kinase gene programmed by CM extracts is delayed 2 min relative to the immediate initiation of transcription of the deoxynucleotide kinase gene programmed by 3-min extracts. These experiments duplicated in vitro effects of the antibiotics on the synthesis of phage-specific mRNA previously noted only in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367905"}
{"pmid": "4367907", "title": "Growth in agarose of human cells infected with cytomegalovirus.", "content": "Growth in agarose of human cells infected with cytomegalovirus. After infection by human cytomegalovirus (CMV), human diploid fibroblasts could grow in agarose medium for several generations. Clones of infected cells grew for weeks, although in every case they ultimately underwent lysis owing to the cytopathic effect of the virus. Virus was inoculated at high dilution and after UV irradiation in an effort to derive cells infected with noninfectious defective particles still capable of inducing cell stimulation. Dilute or irradiated virus occasionally yielded large colonies of replicating cells, although permanent transformation was not observed. One clone derived from UV-CMV-infected cells was passaged four times before undergoing lysis. During these passages the cells exhibited alterations in morphology and orientation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367907"}
{"pmid": "4367916", "title": "Improving emergency-room patient follow-up in a metropolitan teaching hospital. Effect of a follow-up check.", "content": "Improving emergency-room patient follow-up in a metropolitan teaching hospital. Effect of a follow-up check.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367916"}
{"pmid": "4367917", "title": "The renin-angiotensin system (first of two parts).", "content": "The renin-angiotensin system (first of two parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367917"}
{"pmid": "4367919", "title": "The preparation of brush border membranes from rat kidney using an aqueous two-phase polymer system.", "content": "The preparation of brush border membranes from rat kidney using an aqueous two-phase polymer system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367919"}
{"pmid": "4367918", "title": "A comparative study of two structurally related analogs of Asp1-Ile5-angiotensin II.", "content": "A comparative study of two structurally related analogs of Asp1-Ile5-angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367918"}
{"pmid": "4367920", "title": "Relative contributions of Ca2+ influx and cellular Ca2+ release during drug induced activation of the rabbit aorta.", "content": "Relative contributions of Ca2+ influx and cellular Ca2+ release during drug induced activation of the rabbit aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367920"}
{"pmid": "4367922", "title": "Platelet adenylate cyclase responses in depression: implications for a receptor defect.", "content": "Platelet adenylate cyclase responses in depression: implications for a receptor defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367922"}
{"pmid": "4367944", "title": "Serum concentrations of beta-melanocyte-stimulating hormone in human pregnancy.", "content": "Serum concentrations of beta-melanocyte-stimulating hormone in human pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367944"}
{"pmid": "4367945", "title": "Study of serum lipid and blood fibrinolytic activity in cases of cerebral venous-venous sinus thrombosis during the puerperium.", "content": "Study of serum lipid and blood fibrinolytic activity in cases of cerebral venous-venous sinus thrombosis during the puerperium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367945"}
{"pmid": "4367946", "title": "Acute endogenous panophthalmitis caused by Clostridium perfringens.", "content": "Acute endogenous panophthalmitis caused by Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367946"}
{"pmid": "4367948", "title": "Cell wall formation in zoospores of Allomyces arbuscula. I. Fine structural observations on encysting haploid zoospores.", "content": "Cell wall formation in zoospores of Allomyces arbuscula. I. Fine structural observations on encysting haploid zoospores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367948"}
{"pmid": "4367949", "title": "Experimental vitreous surgery in monkeys. IX. Pars plana approach in open-sky technique.", "content": "Experimental vitreous surgery in monkeys. IX. Pars plana approach in open-sky technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367949"}
{"pmid": "4367950", "title": "Cornea and sclera.", "content": "Cornea and sclera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367950"}
{"pmid": "4367951", "title": "The concept of social dominance.", "content": "The concept of social dominance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367951"}
{"pmid": "4367952", "title": "Molecular modifications of anti-aldosterone compounds: effects on affinity of spirolactones for renal aldosterone receptors.", "content": "Molecular modifications of anti-aldosterone compounds: effects on affinity of spirolactones for renal aldosterone receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367952"}
{"pmid": "4367953", "title": "Effects of SC-26096(2-methyl-3-oxo-2azabicyclo(2.2.2.)octan-6-exo-yl 5-(4-biphenylyl)-3-methyl valerate), a new hypolipidemic agent, on mitochondrial respiration and oxidative phosphorylation.", "content": "Effects of SC-26096(2-methyl-3-oxo-2azabicyclo(2.2.2.)octan-6-exo-yl 5-(4-biphenylyl)-3-methyl valerate), a new hypolipidemic agent, on mitochondrial respiration and oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367953"}
{"pmid": "4367954", "title": "Effects of opioid narcotic drugs on energy reserves of skeletal muscle. II. Further studies of the glycogenolytic action of methadone.", "content": "Effects of opioid narcotic drugs on energy reserves of skeletal muscle. II. Further studies of the glycogenolytic action of methadone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367954"}
{"pmid": "4367955", "title": "Further studies on the inhibition of drug metabolism by pregnanolone and related steroids.", "content": "Further studies on the inhibition of drug metabolism by pregnanolone and related steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367955"}
{"pmid": "4367956", "title": "A new phosphodiesterase inhibitor in human lymphocytes: N-methyl-isatin-beta-thiosemicarbazone.", "content": "A new phosphodiesterase inhibitor in human lymphocytes: N-methyl-isatin-beta-thiosemicarbazone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367956"}
{"pmid": "4367957", "title": "Deoxythymidine triphosphate-deoxyuridine triphosphate nucleotidohydrolase induced by Bacillus subtilis bacteriophage phie.", "content": "Deoxythymidine triphosphate-deoxyuridine triphosphate nucleotidohydrolase induced by Bacillus subtilis bacteriophage phie.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367957"}
{"pmid": "4367958", "title": "The triplet state of reaction center bacteriochlorophyll: determination of a relative quantum yeild.", "content": "The triplet state of reaction center bacteriochlorophyll: determination of a relative quantum yeild.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367958"}
{"pmid": "4367959", "title": "Biochemical and biophysical studies on cytochrome C oxidase. XIV. The reaction with cytochrome as studied by pulse radiolysis.", "content": "Biochemical and biophysical studies on cytochrome C oxidase. XIV. The reaction with cytochrome as studied by pulse radiolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367959"}
{"pmid": "4367960", "title": "Biochemical and biophysical studies on cytochrome oxidase. XV. Reaction with fluoride.", "content": "Biochemical and biophysical studies on cytochrome oxidase. XV. Reaction with fluoride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367960"}
{"pmid": "4367961", "title": "Properties of the cytochrome a-like material developed in the photosynthetic bacterium Rhodopseudomonas spheroides when grown aerobically.", "content": "Properties of the cytochrome a-like material developed in the photosynthetic bacterium Rhodopseudomonas spheroides when grown aerobically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367961"}
{"pmid": "4367963", "title": "Light-induced absorbance changes in chloroplasts mediated by photosystem I and photosystem II at low temperature.", "content": "Light-induced absorbance changes in chloroplasts mediated by photosystem I and photosystem II at low temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367963"}
{"pmid": "4367962", "title": "Characterization of a mutant of Schizosaccharomyces pombe lacking cytochrome b-566.", "content": "Characterization of a mutant of Schizosaccharomyces pombe lacking cytochrome b-566.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367962"}
{"pmid": "4367964", "title": "Oxidation of reduced nicotinamide-adenine dinucleotide by the malate-aspartate shuttle in Ehrlich ascites tumour cells.", "content": "Oxidation of reduced nicotinamide-adenine dinucleotide by the malate-aspartate shuttle in Ehrlich ascites tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367964"}
{"pmid": "4367967", "title": "Microbiological transformation of prostaglandins. II. Stereospecific reduction of A (plus or minus)-delta 8(12)-15-dehydroprostaglandin.", "content": "Microbiological transformation of prostaglandins. II. Stereospecific reduction of A (plus or minus)-delta 8(12)-15-dehydroprostaglandin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367967"}
{"pmid": "4367966", "title": "Metabolism of prostaglandin F2alpha in the rat.", "content": "Metabolism of prostaglandin F2alpha in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367966"}
{"pmid": "4367968", "title": "Mechanism of biohydrogenation of cholesterol to coprostanol by Eubacterium ATCC 21408.", "content": "Mechanism of biohydrogenation of cholesterol to coprostanol by Eubacterium ATCC 21408.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367968"}
{"pmid": "4367965", "title": "The distribution of molecular species of monoglycosylceramides (cerebrosides) in different parts of bovine digestive tract.", "content": "The distribution of molecular species of monoglycosylceramides (cerebrosides) in different parts of bovine digestive tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367965"}
{"pmid": "4367969", "title": "The acute action of adrenocorticotropic hormone on adrenal steroidogenesis.", "content": "The acute action of adrenocorticotropic hormone on adrenal steroidogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367969"}
{"pmid": "4367970", "title": "On the solubility, stability and partial purification of CDPdiacyl-sn-glycerol: inositol transferase from rat brain.", "content": "On the solubility, stability and partial purification of CDPdiacyl-sn-glycerol: inositol transferase from rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367970"}
{"pmid": "4367972", "title": "Biochemical changes in Bifidobacterium bifidum var. Pennsylvanicus after cell wall inhibition. VII. Structure of the phosphogalactolipids.", "content": "Biochemical changes in Bifidobacterium bifidum var. Pennsylvanicus after cell wall inhibition. VII. Structure of the phosphogalactolipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367972"}
{"pmid": "4367971", "title": "Affinity chromatography of 3-oxosteroid delta4--delta5-isomerase of Pseudomonas testosteroni.", "content": "Affinity chromatography of 3-oxosteroid delta4--delta5-isomerase of Pseudomonas testosteroni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367971"}
{"pmid": "4367973", "title": "Sulfatides of hog gastric mucosa.", "content": "Sulfatides of hog gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367973"}
{"pmid": "4367974", "title": "Microsomal synthesis of the ether analogs of triacylglycerols. Acyl CoA:alkylacylglycerol and acyl CoA:alk-i-enylacylglycerol acyltransferases in tumors and liver.", "content": "Microsomal synthesis of the ether analogs of triacylglycerols. Acyl CoA:alkylacylglycerol and acyl CoA:alk-i-enylacylglycerol acyltransferases in tumors and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367974"}
{"pmid": "4367975", "title": "The effect of premixing on the oxidation of ethanol by liver alcohol dehydrogenase.", "content": "The effect of premixing on the oxidation of ethanol by liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367975"}
{"pmid": "4367976", "title": "The inhibition of malate dehydrogenase by chlorammine-platinum complexes.", "content": "The inhibition of malate dehydrogenase by chlorammine-platinum complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367976"}
{"pmid": "4367977", "title": "Lipoamide dehydrogenase of the phytopathogenic fungi Pythium ultimum and Phytophthora erythroseptica. Differences in conformation and kinetics.", "content": "Lipoamide dehydrogenase of the phytopathogenic fungi Pythium ultimum and Phytophthora erythroseptica. Differences in conformation and kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367977"}
{"pmid": "4367978", "title": "Studies on glycogen synthase D phosphatase of rat liver--multiple nature.", "content": "Studies on glycogen synthase D phosphatase of rat liver--multiple nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367978"}
{"pmid": "4367979", "title": "Competition of inorganic pyrophosphate and a phosphomonoester as substrates for human placental alkaline orthophosphatase.", "content": "Competition of inorganic pyrophosphate and a phosphomonoester as substrates for human placental alkaline orthophosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367979"}
{"pmid": "4367980", "title": "Solid-phase radioimmunoassay of rat skin collagenase. Comparative studies and in vivo measurement of the enzyme.", "content": "Solid-phase radioimmunoassay of rat skin collagenase. Comparative studies and in vivo measurement of the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367980"}
{"pmid": "4367981", "title": "Separation of multiple dihydrotestosterone receptors in rat ventral prostate by a novel micromethod of electrofocusing. Blocking action of cyproterone acetate and uptake by nuclear chromatin.", "content": "Separation of multiple dihydrotestosterone receptors in rat ventral prostate by a novel micromethod of electrofocusing. Blocking action of cyproterone acetate and uptake by nuclear chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367981"}
{"pmid": "4367982", "title": "The quaternary structure of lactate dehydrogenase. II. The mechanisms, kinetics and thermodynamics of dissociation, denaturation and hybridization in ethylene glycol.", "content": "The quaternary structure of lactate dehydrogenase. II. The mechanisms, kinetics and thermodynamics of dissociation, denaturation and hybridization in ethylene glycol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367982"}
{"pmid": "4367983", "title": "Electron paramagnetic resonance studies on the copper(II) substituted alkaline phosphatase from Escherichia coli.", "content": "Electron paramagnetic resonance studies on the copper(II) substituted alkaline phosphatase from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367983"}
{"pmid": "4367984", "title": "Two copper-containing proteins from cucumber (Cucumis sativus).", "content": "Two copper-containing proteins from cucumber (Cucumis sativus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367984"}
{"pmid": "4367985", "title": "Histone and casein kinases of lactating bovine mammary gland.", "content": "Histone and casein kinases of lactating bovine mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367985"}
{"pmid": "4367986", "title": "Protein disposition in biological membranes.", "content": "Protein disposition in biological membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367986"}
{"pmid": "4367987", "title": "The distribution of noradrenergic nerves and small, intensely fluorescent (SIF) cells in the cat urinary bladder. A light and electron microscope study.", "content": "The distribution of noradrenergic nerves and small, intensely fluorescent (SIF) cells in the cat urinary bladder. A light and electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367987"}
{"pmid": "4367988", "title": "Ultrastructural study of pigment cells of human red hair.", "content": "Ultrastructural study of pigment cells of human red hair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367988"}
{"pmid": "4367989", "title": "Ultrastructure of rat pituitary gonadotrophs following incubations of the gland with synthetic LH-RH.", "content": "Ultrastructure of rat pituitary gonadotrophs following incubations of the gland with synthetic LH-RH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367989"}
{"pmid": "4367990", "title": "The role of the nervous system in regeneration, growth and cell differentiation in Hydra. II. Ultrastructural study of nerve cell elements during hypostomal regeneration.", "content": "The role of the nervous system in regeneration, growth and cell differentiation in Hydra. II. Ultrastructural study of nerve cell elements during hypostomal regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367990"}
{"pmid": "4367991", "title": "Electron microscopical and cytochemical study of vitelline cells in the fresh water triclad Dugesia lugubris s. 1. I. Origin and morphogenesis of cocoon-shell globules.", "content": "Electron microscopical and cytochemical study of vitelline cells in the fresh water triclad Dugesia lugubris s. 1. I. Origin and morphogenesis of cocoon-shell globules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367991"}
{"pmid": "4367992", "title": "In vitro maturation of Arbacia punctulata oocytes and initiation of heavy body formation. An ultrastructural study.", "content": "In vitro maturation of Arbacia punctulata oocytes and initiation of heavy body formation. An ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367992"}
{"pmid": "4367993", "title": "Electrophoretic patterns of blood serum proteins of the cyprinid fish, Leuciscus leuciscus (L.).", "content": "Electrophoretic patterns of blood serum proteins of the cyprinid fish, Leuciscus leuciscus (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367993"}
{"pmid": "4367994", "title": "Organophosphate splitting serum enzymes in different mammals.", "content": "Organophosphate splitting serum enzymes in different mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367994"}
{"pmid": "4367995", "title": "Inhibition of the angiotensin I converting enzyme of the lung by a peptide fragment of bradykinin.", "content": "Inhibition of the angiotensin I converting enzyme of the lung by a peptide fragment of bradykinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367995"}
{"pmid": "4367996", "title": "The effect of hydrocortisone on tension and cyclic AMP metabolism in tracheal smooth muscle.", "content": "The effect of hydrocortisone on tension and cyclic AMP metabolism in tracheal smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367996"}
{"pmid": "4367997", "title": "Paracrystalline inclusions in mitochondria of frog oocytes.", "content": "Paracrystalline inclusions in mitochondria of frog oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367997"}
{"pmid": "4367998", "title": "Stimulation of cell aggregation by theophylline in the asexual reproduction of fresh-water sponges (Ephydatia fluviatilis).", "content": "Stimulation of cell aggregation by theophylline in the asexual reproduction of fresh-water sponges (Ephydatia fluviatilis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367998"}
{"pmid": "4367999", "title": "Epstein-Barr virus-binding receptor on the surface of chronic lymphocytic leukaemic lymphocytes.", "content": "Epstein-Barr virus-binding receptor on the surface of chronic lymphocytic leukaemic lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4367999"}
{"pmid": "4368000", "title": "Cyclic guanosine 3',5'-monophosphate and gallbladder contraction.", "content": "Cyclic guanosine 3',5'-monophosphate and gallbladder contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368000"}
{"pmid": "4368001", "title": "Inherited hyperammonemic syndromes.", "content": "Inherited hyperammonemic syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368001"}
{"pmid": "4368002", "title": "Cross-reactions between human and animal plasma proteins. VI. An assay method for ape and monkey plasma proteins using antihuman antisera.", "content": "Cross-reactions between human and animal plasma proteins. VI. An assay method for ape and monkey plasma proteins using antihuman antisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368002"}
{"pmid": "4368003", "title": "Metastasis of mammary carcinoma to the mandibular condyle.", "content": "Metastasis of mammary carcinoma to the mandibular condyle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368003"}
{"pmid": "4368004", "title": "Spontaneous conductance changes, multilevel conductance states and negative differential resistance in oxidized cholesterol black lipid membranes.", "content": "Spontaneous conductance changes, multilevel conductance states and negative differential resistance in oxidized cholesterol black lipid membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368004"}
{"pmid": "4368005", "title": "Localization of a calcium-stimulated ATPase in the basal-lateral plasma membranes of the proximal tubule of rat kidney cortex.", "content": "Localization of a calcium-stimulated ATPase in the basal-lateral plasma membranes of the proximal tubule of rat kidney cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368005"}
{"pmid": "4368006", "title": "Polar lipid composition of the leaves and seeds from the tea plant (Camellia sinensis L).", "content": "Polar lipid composition of the leaves and seeds from the tea plant (Camellia sinensis L).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368006"}
{"pmid": "4368008", "title": "To spritz or not to spritz: the doubtful value of aimless iontophoresis.", "content": "To spritz or not to spritz: the doubtful value of aimless iontophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368008"}
{"pmid": "4368010", "title": "A 7S DNA polymerase in the cytoplasmic fraction from higher plant.", "content": "A 7S DNA polymerase in the cytoplasmic fraction from higher plant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368010"}
{"pmid": "4368009", "title": "The role of the first component of the bovine complement system in the haemolytic activity of a bovine derived lytic intermediate.", "content": "The role of the first component of the bovine complement system in the haemolytic activity of a bovine derived lytic intermediate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368009"}
{"pmid": "4368012", "title": "Changes in electrolyte excretion following intraperitoneal injection of dibutyryl cyclic AMP in the brattleboro rat.", "content": "Changes in electrolyte excretion following intraperitoneal injection of dibutyryl cyclic AMP in the brattleboro rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368012"}
{"pmid": "4368011", "title": "Renal effects of cyclic AMP in normal and congenital diabetes insipidus rats.", "content": "Renal effects of cyclic AMP in normal and congenital diabetes insipidus rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368011"}
{"pmid": "4368013", "title": "Virus-associated enzymes.", "content": "Virus-associated enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368013"}
{"pmid": "4368014", "title": "Kinetic and metabolic studies of Prostaglandin F2-alpha administered intra-amniotically for induction of abortion.", "content": "Kinetic and metabolic studies of Prostaglandin F2-alpha administered intra-amniotically for induction of abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368014"}
{"pmid": "4368017", "title": "Decreased adrenal sensitivity to ACTH in the vasopressin-deficient (Brattleboro) rat.", "content": "Decreased adrenal sensitivity to ACTH in the vasopressin-deficient (Brattleboro) rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368017"}
{"pmid": "4368018", "title": "Differential localization of the influence of lysine vasopressin and of ACTH 4-10 on avoidance behavior: a study in rats bearing lesions in the parafascicular nuclei.", "content": "Differential localization of the influence of lysine vasopressin and of ACTH 4-10 on avoidance behavior: a study in rats bearing lesions in the parafascicular nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368018"}
{"pmid": "4368019", "title": "Hypothalamic control of aldosterone production in sodium-deficient rats.", "content": "Hypothalamic control of aldosterone production in sodium-deficient rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368019"}
{"pmid": "4368020", "title": "Brain monoamines and endocrine function.", "content": "Brain monoamines and endocrine function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368020"}
{"pmid": "4368021", "title": "Neuroendocrine transduction.", "content": "Neuroendocrine transduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368021"}
{"pmid": "4368022", "title": "Possible function of monoamines as neurotransmitters.", "content": "Possible function of monoamines as neurotransmitters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368022"}
{"pmid": "4368023", "title": "Possible sites of action of monoamines in hypothalamohypophyseal function.", "content": "Possible sites of action of monoamines in hypothalamohypophyseal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368023"}
{"pmid": "4368024", "title": "Neuroendocrine transducer input-output relations.", "content": "Neuroendocrine transducer input-output relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368024"}
{"pmid": "4368025", "title": "Monoamines and control of glucocorticoid secretion from the adrenal cortex.", "content": "Monoamines and control of glucocorticoid secretion from the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368025"}
{"pmid": "4368026", "title": "Gonad function and tuberoinfundibular dopamine.", "content": "Gonad function and tuberoinfundibular dopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368026"}
{"pmid": "4368027", "title": "Lesion effects on hypothalamohypophyseal function.", "content": "Lesion effects on hypothalamohypophyseal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368027"}
{"pmid": "4368028", "title": "Brain monoamines and endocrine function. Conclusions.", "content": "Brain monoamines and endocrine function. Conclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368028"}
{"pmid": "4368029", "title": "A special baby visitor.", "content": "A special baby visitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368029"}
{"pmid": "4368032", "title": "Permeability and other properties of the outer mitochondrial membrane.", "content": "Permeability and other properties of the outer mitochondrial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368032"}
{"pmid": "4368031", "title": "Antiviral activities of silver sulfadiazine in ocular infection.", "content": "Antiviral activities of silver sulfadiazine in ocular infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368031"}
{"pmid": "4368036", "title": "\"Cri du chat\" syndrome with maternal insertional translocation.", "content": "\"Cri du chat\" syndrome with maternal insertional translocation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368036"}
{"pmid": "4368035", "title": "'Stress' hormones and lipid metabolism.", "content": "'Stress' hormones and lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368035"}
{"pmid": "4368034", "title": "Permeability of capillaries to different tracers and uptake of horseradish peroxidase by the secretory cells in rat anterior pituitary gland.", "content": "Permeability of capillaries to different tracers and uptake of horseradish peroxidase by the secretory cells in rat anterior pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368034"}
{"pmid": "4368227", "title": "[Probable existence of hexosaminidase C locus located on chromosome 7 in man].", "content": "[Probable existence of hexosaminidase C locus located on chromosome 7 in man].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368227"}
{"pmid": "4368290", "title": "[Tissue culture of viruses (author's transl)].", "content": "[Tissue culture of viruses (author's transl)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368290"}
{"pmid": "4368313", "title": "A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants.", "content": "A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368313"}
{"pmid": "4368314", "title": "A catch-up phenomenon in skeletal development of children with Down's syndrome.", "content": "A catch-up phenomenon in skeletal development of children with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368314"}
{"pmid": "4368316", "title": "A chromatographic method of assay of colchicine alkaloid.", "content": "A chromatographic method of assay of colchicine alkaloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368316"}
{"pmid": "4368315", "title": "A chickenpox epidemic in a pediatric burn unit.", "content": "A chickenpox epidemic in a pediatric burn unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368315"}
{"pmid": "4368317", "title": "A comparative histochemical study of some oxidative and hydrolytic enzymes in the kidneys of domestic food animals, laboratory animals and the fowl.", "content": "A comparative histochemical study of some oxidative and hydrolytic enzymes in the kidneys of domestic food animals, laboratory animals and the fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368317"}
{"pmid": "4368319", "title": "A comparison of graduate and recidivist WISC IQ scores in a delinquency treatment program for girls.", "content": "A comparison of graduate and recidivist WISC IQ scores in a delinquency treatment program for girls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368319"}
{"pmid": "4368318", "title": "A comparative study of viruses associated with acute haemorrhagic conjunctivitis.", "content": "A comparative study of viruses associated with acute haemorrhagic conjunctivitis. Seven representative isolates from six outbreaks of acute haemorrhagic conjunctivitis were shown to have the characteristics of enteroviruses. Two viruses differed from the remaining five isolates in producing paralysis in suckling mice and being resistant to 2-hydroxybenzyl-benzimidazole. These two viruses were also closely related antigenically and distinct from the other five viruses which were serologically similar to each other. Neither group of viruses was inhibited by antisera to the known enteroviruses and they probably represent two new enterovirus types one related to the Coxsackie A viruses and the other to the echoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368318"}
{"pmid": "4368320", "title": "A comparison of urea and alkali degradation of full and empty bovine enterovirus particles.", "content": "A comparison of urea and alkali degradation of full and empty bovine enterovirus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368320"}
{"pmid": "4368322", "title": "A cytomegalovirus vaccine?", "content": "A cytomegalovirus vaccine?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368322"}
{"pmid": "4368321", "title": "A critical investigation into the antibiotic sterilization of heart valve homografts.", "content": "A critical investigation into the antibiotic sterilization of heart valve homografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368321"}
{"pmid": "4368323", "title": "A deletion mutation placing the galactokinase gene of Escherichia coli under control of the biotin promoter.", "content": "A deletion mutation placing the galactokinase gene of Escherichia coli under control of the biotin promoter. A deletion has been isolated which fuses galK and presumably galT to the promoter and operator of the bioA operon. The deletion has endpoints in bioA and galE, and leaves the operator-proximal end of bioA intact and the regulatory sites themselves functional. In bacterial strains which carry the deletion, the expression of galK is regulated by biotin, although due to the inefficiency of the bioA promoter even the fully derepressed level of galactokinase is low. Electron micrographic examination of the mutation shows that it is a simple deletion, uncomplicated by other chromosomal abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368323"}
{"pmid": "4368326", "title": "A family study of 50 REM narcoleptics.", "content": "A family study of 50 REM narcoleptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368326"}
{"pmid": "4368324", "title": "A demonstration of several deoxyribonuclease activities in mammalian cell mitochondria.", "content": "A demonstration of several deoxyribonuclease activities in mammalian cell mitochondria. Extracts of purified mitochondria from adult rabbit liver and kidney have been prepared by lysis with Triton X-100. Such extracts contain deoxyribonuclease activity demonstrable at alkaline pH. Studies utilizing the effects of substrate variation, differing ionic strength, nucleoside di- and triphosphates, and SH-group inhibitors reveal the existence of at least five distinguishable deoxyribonuclease activities in these extracts. Assay of lysosomal and mitochondrial enzyme markers indicates no significant lysosomal contamination of the mitochondrial extracts. Further studies also suggest that the alkaline deoxyribonuclease activity is specifically located in or in association with mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368324"}
{"pmid": "4368327", "title": "A filter assay for the sex steroid binding protein (SBP) of human serum.", "content": "A filter assay for the sex steroid binding protein (SBP) of human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368327"}
{"pmid": "4368325", "title": "A differential effect of chronically administered guanethidine on sympathetic neurotransmission to the dog heart and mesenteric arterial blood vessels.", "content": "A differential effect of chronically administered guanethidine on sympathetic neurotransmission to the dog heart and mesenteric arterial blood vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368325"}
{"pmid": "4368328", "title": "A health and seroepidemiological survey of a community in Barbados.", "content": "A health and seroepidemiological survey of a community in Barbados.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368328"}
{"pmid": "4368330", "title": "A method for the implanation of solid and liquid materials in the marrow cavity of the femur of small laboratory animals.", "content": "A method for the implanation of solid and liquid materials in the marrow cavity of the femur of small laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368330"}
{"pmid": "4368329", "title": "A large hepatoma without apparent abnormality on laparotomy.", "content": "A large hepatoma without apparent abnormality on laparotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368329"}
{"pmid": "4368331", "title": "A modified tendon transference for radial nerve paralysis.", "content": "A modified tendon transference for radial nerve paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368331"}
{"pmid": "4368332", "title": "A modified two-dimensional gel system for the separation and radioautography of microgram amounts of ribosomal proteins.", "content": "A modified two-dimensional gel system for the separation and radioautography of microgram amounts of ribosomal proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368332"}
{"pmid": "4368333", "title": "A molecular theory of lipid-protein interactions in the plasma lipoproteins.", "content": "A molecular theory of lipid-protein interactions in the plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368333"}
{"pmid": "4368335", "title": "A new approach to the study of nucleotide sequences in DNA: the analysis of termini formed by DNases.", "content": "A new approach to the study of nucleotide sequences in DNA: the analysis of termini formed by DNases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368335"}
{"pmid": "4368334", "title": "A new acid hydrolysis method for determining tryptophan in peptides and proteins.", "content": "A new acid hydrolysis method for determining tryptophan in peptides and proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368334"}
{"pmid": "4368336", "title": "A new assay of cyclic nucleotide phosphodiesterase; its application to human serum.", "content": "A new assay of cyclic nucleotide phosphodiesterase; its application to human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368336"}
{"pmid": "4368337", "title": "A new procedure for the two-dimensional display of the molecular size-electric charge characteristics of native proteins in crude mixtures.", "content": "A new procedure for the two-dimensional display of the molecular size-electric charge characteristics of native proteins in crude mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368337"}
{"pmid": "4368338", "title": "A new purine ring closure and the synthesis of 2-substituted derivatives of adenosine cyclic 3',5'-phosphate.", "content": "A new purine ring closure and the synthesis of 2-substituted derivatives of adenosine cyclic 3',5'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368338"}
{"pmid": "4368339", "title": "A nuclear magnetic relaxation study of Co(II) bovine superoxide dismutase. Evidence that the Co(II) site is exchange-coupled to the copper and not accessible to the solvent.", "content": "A nuclear magnetic relaxation study of Co(II) bovine superoxide dismutase. Evidence that the Co(II) site is exchange-coupled to the copper and not accessible to the solvent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368339"}
{"pmid": "4368340", "title": "A parasitological survey of a village in a mountain district of Papua.", "content": "A parasitological survey of a village in a mountain district of Papua.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368340"}
{"pmid": "4368341", "title": "A possible biological function of the protein kinase associated with vaccinia and vesicular stomatitis virions.", "content": "A possible biological function of the protein kinase associated with vaccinia and vesicular stomatitis virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368341"}
{"pmid": "4368342", "title": "A probable mechanism for apurinic acid inhibition of DNA synthesis.", "content": "A probable mechanism for apurinic acid inhibition of DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368342"}
{"pmid": "4368343", "title": "A pure sign of lumbrical function.", "content": "A pure sign of lumbrical function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368343"}
{"pmid": "4368345", "title": "A quantitative approach to habituation and to evaluation of the effects of noisy neural pathways in a crayfish system.", "content": "A quantitative approach to habituation and to evaluation of the effects of noisy neural pathways in a crayfish system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368345"}
{"pmid": "4368344", "title": "A qualification to the use of TEA as a tracer for monosynaptic pathways.", "content": "A qualification to the use of TEA as a tracer for monosynaptic pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368344"}
{"pmid": "4368346", "title": "A radioimmunoassay for serum dehydroepiandrosterone.", "content": "A radioimmunoassay for serum dehydroepiandrosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368346"}
{"pmid": "4368347", "title": "A rapid isolation of phosphoribosyladenosine triphosphate synthetase and comparison to native enzyme.", "content": "A rapid isolation of phosphoribosyladenosine triphosphate synthetase and comparison to native enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368347"}
{"pmid": "4368348", "title": "A re-evaluation of the effects of lesions of the pontine tegmentum and locus coeruleus on phenomena of paradoxical sleep in the cat.", "content": "A re-evaluation of the effects of lesions of the pontine tegmentum and locus coeruleus on phenomena of paradoxical sleep in the cat. Bilateral lesions placed in the pontiene tegmentum resulted in episodes of paradoxical sleep in which the characteristic atonia of that sleep stage was absent in six cats. Following each period of synchronized sleep, in which the degree of muscle tone of the dorsal cervical muscles gradually diminished, cats with such lesions would slowly raise their heads, move their limbs at all joints, make several attempts to rise and eventually leap violently. During such episodes they were unresponsive to strong lights, touching and mild pinching. Only sound would arouse them. This behavior appeared as early as the 2nd postoperative day, the 1st day of recording. Such episodes supplanted normal paradoxical sleep with atonia and lasted unchanged for as long as 6 months in one cat until it was killed while still in good health. Complete recovery of atonia was observed in one cat after 3 weeks. Either no recovery or else eventual recovery to excessively active periods of paradoxical sleep while remaining recumbent characterized the sleep of the other four. The conclusion drawn from these experiments and from a review of the literature is that the hypotheses stating that the locus coeruleus or other isolated nuclei of the pons are specifically concerned with the initiation of paradoxical sleep are not clearly supported by available evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368348"}
{"pmid": "4368349", "title": "A resolution of conflicting reports concerning the mode of action of fusidic acid.", "content": "A resolution of conflicting reports concerning the mode of action of fusidic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368349"}
{"pmid": "4368350", "title": "A retrospective study of lung cancer in Bombay.", "content": "A retrospective study of lung cancer in Bombay. This is a retrospective study of 520 patients with lung cancer, seen at the Tata Memorial Hospital between 1963 and 1970. Matched controls were obtained from those patients who came to the hospital within the same period and who were diagnosed as not having cancer. The patients and controls were matched for age, sex and community. As reported in other studies, an association was found between smoking habit and lung cancer. The relative risk of all types of smokers to non-smokers is 2·45, of bidi smokers 2·64 and of cigarette smokers 2·23. There is a preponderance of the group of epidermoid carcinomata among smokers as against adenocarcinomata. The probable reasons for the reported low incidence of lung cancer in this population have been discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368350"}
{"pmid": "4368351", "title": "A role of the carbohydrate moiety of glucose oxidase: kinetic evidence for protection of the enzyme from thermal inactivation in the presence of sodium dodecyl sulfate.", "content": "A role of the carbohydrate moiety of glucose oxidase: kinetic evidence for protection of the enzyme from thermal inactivation in the presence of sodium dodecyl sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368351"}
{"pmid": "4368352", "title": "A semi-automated in vitro assay for CRF: activities of peptides related to oxytocin and vasopressin.", "content": "A semi-automated in vitro assay for CRF: activities of peptides related to oxytocin and vasopressin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368352"}
{"pmid": "4368353", "title": "A sensitive method for the detection of corticotrophin releasing factor using a perfused pituitary cell column.", "content": "A sensitive method for the detection of corticotrophin releasing factor using a perfused pituitary cell column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368353"}
{"pmid": "4368354", "title": "A serologic study on cytomegalovirus infection associated with blood transfusion in Japanese.", "content": "A serologic study on cytomegalovirus infection associated with blood transfusion in Japanese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368354"}
{"pmid": "4368355", "title": "A simple modification of the Tudor Thomas eye piece stand.", "content": "A simple modification of the Tudor Thomas eye piece stand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368355"}
{"pmid": "4368356", "title": "A simplified technique for hepatic resection: the crush method.", "content": "A simplified technique for hepatic resection: the crush method. A new technique of hepatic lobectomy with combined use of hepatic clamp and liver crush clamp is described. It is a simplification of the original finger fracture technique by using instruments instead of fingers for hepatic resection. It provides the unexperienced with a technique of hepatic resection done in the shortest possible time and in an almost bloodless field with safety. Since February 1973 the author has performed 5 hepatic resections with this crush method for primary liver cell carcinoma. The blood transfusion averaged 200 ml and the operation time averaged 1.5 hours. No complication or mortality was encountered and the patients were invariably discharged within 14 days after the operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368356"}
{"pmid": "4368357", "title": "A small portable centrifugal fast analyzer system.", "content": "A small portable centrifugal fast analyzer system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368357"}
{"pmid": "4368358", "title": "A special program for nurse addicts.", "content": "A special program for nurse addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368358"}
{"pmid": "4368360", "title": "A thermodynamic approach to the problem of stabilization of globular protein structure: a calorimetric study.", "content": "A thermodynamic approach to the problem of stabilization of globular protein structure: a calorimetric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368360"}
{"pmid": "4368359", "title": "A spectrophotometric assay of beta-lactamase action on penicillins.", "content": "A spectrophotometric assay of beta-lactamase action on penicillins. A new method for measuring the enzymic hydrolysis of the beta-lactam ring in penicillins is described. The change in extinction in the u.v. region is determined. The method is sensitive (50mum-benzylpenicillin can be used) and convenient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368359"}
{"pmid": "4368362", "title": "Abortive infection and transformation of human embryonic fibroblasts by Molluscum contagiosum virus.", "content": "Abortive infection and transformation of human embryonic fibroblasts by Molluscum contagiosum virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368362"}
{"pmid": "4368361", "title": "A transmissible antigen detected in two cell lines derived from human tumours.", "content": "A transmissible antigen detected in two cell lines derived from human tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368361"}
{"pmid": "4368365", "title": "Acidic nuclear protein synthesis in Rous Sarcoma virus infected chick embryo fibroblasts.", "content": "Acidic nuclear protein synthesis in Rous Sarcoma virus infected chick embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368365"}
{"pmid": "4368364", "title": "Accumulation and metabolism of 3H-epinephrine by the rat heart during variable states of adrenocortical function.", "content": "Accumulation and metabolism of 3H-epinephrine by the rat heart during variable states of adrenocortical function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368364"}
{"pmid": "4368363", "title": "Acceleration of sugar transport in avian erythrocytes by catecholamines.", "content": "Acceleration of sugar transport in avian erythrocytes by catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368363"}
{"pmid": "4368366", "title": "Action of 'diamide' on some energy linked processes of rat liver mitochondria.", "content": "Action of 'diamide' on some energy linked processes of rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368366"}
{"pmid": "4368367", "title": "Action of cyclic 3',5' adenosine monophosphate on the uterus of the ovariectomized rat.", "content": "Action of cyclic 3',5' adenosine monophosphate on the uterus of the ovariectomized rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368367"}
{"pmid": "4368368", "title": "Activation by reductive cleavage of potentially cytotoxic azo compounds by human hepatocellular carcinoma.", "content": "Activation by reductive cleavage of potentially cytotoxic azo compounds by human hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368368"}
{"pmid": "4368369", "title": "Activation of cholesteryl esterase in bovine adrenal cortex.", "content": "Activation of cholesteryl esterase in bovine adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368369"}
{"pmid": "4368370", "title": "Activation of latent collagenase by microbial plaque.", "content": "Activation of latent collagenase by microbial plaque.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368370"}
{"pmid": "4368371", "title": "Activation of the peripheral lymphocytes in the course of the immune response to transplanted SV40-transformed tumour cells in hamsters.", "content": "Activation of the peripheral lymphocytes in the course of the immune response to transplanted SV40-transformed tumour cells in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368371"}
{"pmid": "4368372", "title": "Activation of transcription at specific promoters by glycerol.", "content": "Activation of transcription at specific promoters by glycerol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368372"}
{"pmid": "4368374", "title": "Adenosine 3',5'-cyclic phosphorothioate: synthesis and biological properties.", "content": "Adenosine 3',5'-cyclic phosphorothioate: synthesis and biological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368374"}
{"pmid": "4368377", "title": "Adenylate cyclase assay with adenylyl imidodiphosphate and product detection by competitive protein binding.", "content": "Adenylate cyclase assay with adenylyl imidodiphosphate and product detection by competitive protein binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368377"}
{"pmid": "4368376", "title": "Adenyl cyclase and the cyclic AMP responsive systems in the uterus.", "content": "Adenyl cyclase and the cyclic AMP responsive systems in the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368376"}
{"pmid": "4368375", "title": "Adenovirus polypeptide synthesis in the presence of non-replicating poliovirus.", "content": "Adenovirus polypeptide synthesis in the presence of non-replicating poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368375"}
{"pmid": "4368379", "title": "Adreno-leukodystrophy (sex-linked Schilder disease). Ultrastructural demonstration of specific cytoplasmic inclusions in the central nervous system.", "content": "Adreno-leukodystrophy (sex-linked Schilder disease). Ultrastructural demonstration of specific cytoplasmic inclusions in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368379"}
{"pmid": "4368380", "title": "Adrenocortical function following long-term corticosteroid treatment.", "content": "Adrenocortical function following long-term corticosteroid treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368380"}
{"pmid": "4368373", "title": "Adenocarcinoma of the larynx.", "content": "Adenocarcinoma of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368373"}
{"pmid": "4368381", "title": "Adrenocortical function in the Burmese.", "content": "Adrenocortical function in the Burmese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368381"}
{"pmid": "4368383", "title": "Adriamycin in advanced bronchogenic carcinoma.", "content": "Adriamycin in advanced bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368383"}
{"pmid": "4368384", "title": "Adult lipoid nephrosis: clinicopathological correlations.", "content": "Adult lipoid nephrosis: clinicopathological correlations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368384"}
{"pmid": "4368382", "title": "Adrenocorticotrophic and melanocyte-stimulating peptides in the human pituitary.", "content": "Adrenocorticotrophic and melanocyte-stimulating peptides in the human pituitary. The adrenocorticotrophic and melanocyte-stimulating peptides of the human pituitary were investigated by means of radioimmunoassay, bioassay and physicochemical procedures. Substantial amounts of adrenocorticotrophin and a peptide resembling beta-lipotrophin were identified in pituitary extracts, but alpha-melanocyte-stimulating hormone, beta-melanocyte-stimulating hormone and corticotrophin-like intermediate lobe peptide, which have been identified in the pars intermedia of pituitaries from other vertebrates, were not found. The absence of beta-melanocyte-stimulating hormone appears to contradict previous chemical and radioimmunological studies. Our results suggest, however, that it is not a natural pituitary peptide but an artefact formed by enzymic degradation of beta-lipotrophin during extraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368382"}
{"pmid": "4368386", "title": "Affinity chromatographic differentiation of lactate dehydrogenase isoenzymes on the basis of differential abortive complex formation.", "content": "Affinity chromatographic differentiation of lactate dehydrogenase isoenzymes on the basis of differential abortive complex formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368386"}
{"pmid": "4368385", "title": "Aerial applications of ultra-low-volume insecticides to control the vector of Japanese encephalitis in Korea.", "content": "Aerial applications of ultra-low-volume insecticides to control the vector of Japanese encephalitis in Korea. As a suitable emergency measure to arrest epidemics of Japanese encephalitis in Korea, the ultra-low-volume method of spraying insecticide to control the mosquito vector Culex tritaeniorhynchus has been tested in 2 successive years over a 16-km (2) area, utilizing a large fixed-wing aircraft. Malathion concentrate applied at 0.36 litres/ha gave insufficient control of the parous (infective) females, and no reduction in total numbers of this species. Fenitrothion concentrate applied at 0.45 litres/ha resulted in a 77-87% reduction in total numbers and an 87-98% reduction in parous females over a 4-day period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368385"}
{"pmid": "4368378", "title": "Adrenal steroids in leukemia and lymphoma.", "content": "Adrenal steroids in leukemia and lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368378"}
{"pmid": "4368387", "title": "Affinity chromatography of cytosolic NAD-linked glycerol-3-phosphate dehydrogenase from normal and neoplastic mammalian tissues.", "content": "Affinity chromatography of cytosolic NAD-linked glycerol-3-phosphate dehydrogenase from normal and neoplastic mammalian tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368387"}
{"pmid": "4368389", "title": "Aflatoxin hepatitis (an experimental comparative study).", "content": "Aflatoxin hepatitis (an experimental comparative study).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368389"}
{"pmid": "4368388", "title": "Affinity labeling steroids for characterization of steroid binding sites.", "content": "Affinity labeling steroids for characterization of steroid binding sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368388"}
{"pmid": "4368391", "title": "Aldosterone production by adrenal cultures via dbcAMP, and the reversibility of ACTH and dbcAMP-induced changes.", "content": "Aldosterone production by adrenal cultures via dbcAMP, and the reversibility of ACTH and dbcAMP-induced changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368391"}
{"pmid": "4368390", "title": "Aggressive trends in endocrine surgery.", "content": "Aggressive trends in endocrine surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368390"}
{"pmid": "4368393", "title": "Alleviation of barbiturate inhibition on the oxidative activity of submitochondrial particles by alkali.", "content": "Alleviation of barbiturate inhibition on the oxidative activity of submitochondrial particles by alkali.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368393"}
{"pmid": "4368392", "title": "Alkaline isomerization of ferricytochrome c: identification of the lysine ligand.", "content": "Alkaline isomerization of ferricytochrome c: identification of the lysine ligand. Changes in the visible absorbance spectra of complexes of horse heart cytochrome c hemopeptide 1-65, peptide 66-104, and their guanidinated counterparts are compared with those characteristic of native and fully guanidinated ferricytochrome c over the pH range 7 to 11. Upon raising the pH, the methionine ligand in the guanidinated hemopeptide 1-65.peptide 66-104 complex is replaced by a strong field ligand. By contrast, the methionine ligand in the hemopeptide 1-65.guanidinated peptide 66-104 is replaced by a weak field ligand. These results demonstrate that lysine 13 does not ligate with the heme iron upon isomerization of ferricytochrome c and that the ligand in the horse heart protein is one of the eight lysine residues in the 66-104 segment of the polypeptide, most likely lysine 79.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368392"}
{"pmid": "4368394", "title": "Allyl alcohol-induced irreversible inhibition of yeast alcohol dehydrogenase.", "content": "Allyl alcohol-induced irreversible inhibition of yeast alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368394"}
{"pmid": "4368395", "title": "Alteration of structure of level of threonyl-tRNA-synthetase in Borrelidin resistant mutants of E. coli.", "content": "Alteration of structure of level of threonyl-tRNA-synthetase in Borrelidin resistant mutants of E. coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368395"}
{"pmid": "4368396", "title": "Alveolar cell carcinoma (bronchiolar carcinoma).", "content": "Alveolar cell carcinoma (bronchiolar carcinoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368396"}
{"pmid": "4368397", "title": "An autopsy case of congenital hepatic cell tumor.", "content": "An autopsy case of congenital hepatic cell tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368397"}
{"pmid": "4368399", "title": "An epidemiologic and serologic comparison of uterine carcinoma in situ and squamous dysplasia.", "content": "An epidemiologic and serologic comparison of uterine carcinoma in situ and squamous dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368399"}
{"pmid": "4368398", "title": "An electron microscope study of mitochondrial DNA in spontaneous human tumours and chemically induced animal tumours.", "content": "An electron microscope study of mitochondrial DNA in spontaneous human tumours and chemically induced animal tumours. MtDNA was extracted by a phenol method from transplanted and primary DAB induced hepatomata in male Wistar rats, normal rat liver, spontaneous human tumours (2 Wilm's tumours, one neuroblastoma and one adrenal carcinoma), as well as 2 specimens of normal human kidney, BNU induced \"leukaemias\" in mice and CHO fibroblasts in monolayer culture. The proportion of monomers, catenated dimers and oligomers, open dimers and small circles was determined by electron microscopy of the fractions comprising lower and middle DNA bands in a CsCl-EthBr gradient. Tumours were compared where possible with their normal tissue of origin. Open dimers were found in 2 Wilm's tumours and their attached \"normal-looking\" kidney tissue but not in normal, non-malignant kidney or any other tissue studied. In Wilm's tumours, the occurrence of open dimers is far from being an all-or-none phenomenon. Malignancy produced little change in the relative proportions of catenated dimers and oligomers in the tissues studied. Small circles were found associated with mtDNA from every tissue. Tumour mtDNA was not more heterogeneous in length than monomers from the corresponding normal tissue, neither was the mean length of tumour mtDNA significantly different from its corresponding normal mtDNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368398"}
{"pmid": "4368401", "title": "An improved spectrophotometric assay for ribulosebisphosphate carboxylase.", "content": "An improved spectrophotometric assay for ribulosebisphosphate carboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368401"}
{"pmid": "4368400", "title": "An examination of the constancy of the rate of molecular evolution.", "content": "An examination of the constancy of the rate of molecular evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368400"}
{"pmid": "4368402", "title": "An in vitro study of mineralocorticoid binding proteins from rat kidney.", "content": "An in vitro study of mineralocorticoid binding proteins from rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368402"}
{"pmid": "4368403", "title": "An inactivator for the affinity labelling of adenine nucleotide dependent enzymes.", "content": "An inactivator for the affinity labelling of adenine nucleotide dependent enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368403"}
{"pmid": "4368404", "title": "An investigation of media for the long term storage of three respiratory viruses.", "content": "An investigation of media for the long term storage of three respiratory viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368404"}
{"pmid": "4368406", "title": "An unusual lipid-protein complex observed in an IgG myeloma patient.", "content": "An unusual lipid-protein complex observed in an IgG myeloma patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368406"}
{"pmid": "4368407", "title": "Analysis of intact gangliosides by mass spectrometry. Comparison of different derivatives of a hematoside of a tumour and the major monosialoganglioside of brain.", "content": "Analysis of intact gangliosides by mass spectrometry. Comparison of different derivatives of a hematoside of a tumour and the major monosialoganglioside of brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368407"}
{"pmid": "4368409", "title": "Analysis of molecular species of 2H-labelled phosphatidylcholines by liquid-gel chromatography and gas chromatography-mass spectrometry.", "content": "Analysis of molecular species of 2H-labelled phosphatidylcholines by liquid-gel chromatography and gas chromatography-mass spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368409"}
{"pmid": "4368408", "title": "Analysis of labeled 3' terminal nucleotides of DNA fragments.", "content": "Analysis of labeled 3' terminal nucleotides of DNA fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368408"}
{"pmid": "4368411", "title": "Androgen transport and receptor mechanisms in testis and epididymis.", "content": "Androgen transport and receptor mechanisms in testis and epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368411"}
{"pmid": "4368410", "title": "Analytical study of microsomes and isolated subcellular membranes from rat liver. IV. Biochemical, physical, and morphological modifications of microsomal components induced by digitonin, EDTA, and pyrophosphate.", "content": "Analytical study of microsomes and isolated subcellular membranes from rat liver. IV. Biochemical, physical, and morphological modifications of microsomal components induced by digitonin, EDTA, and pyrophosphate. Isopycnic equilibration and sedimentation rate studies of rat liver microsomes led previously to the assignment of microsomal constituents into group a1 (monoamine oxidase), group a2 (5'-nucleotidase, alkaline phosphodiesterase I, alkaline phosphatase and cholesterol), group a3 (galactosyltransferase), group b (NADH cytochrome c reductase, NADPH cytochrome c reductase, aminopyrine demethylase, cytochrome b(5) and P 450), and group c (glucose 6-phosphatase, esterase, nucleoside diphosphatase, beta-glucuronidase and glucuronyltransferase). Confirmation and extension of the assignment into groups has been obtained by studying the differential effect of the reagents digitonin, EDTA, and PPi. Digitonin specifically affected the equilibrium density only of the group a2 and (to a lesser extent) group a3, and not of groups b and c under conditions which preserved the structure-linked latency of nucleoside diphosphatase and galactosyltransferase. Within experimental error the rate of sedimentation of all microsomal constituents was unaffected. The morphological appearance under the electron microscope was indistinguishable from that of nondigitonin-treated microsomes, except that a few smooth membranes (< 10%) exhibited broken-looking profiles. Treatment of microsomes with EDTA or PPi detached a substantial part of RNA and released protein in excess over the amount accountable for by detachment of ribosome constituents. This detachment was confirmed by electron microscopy. EDTA and PPi decreased markedly the equilibrium density and the density dispersion of groups b and c, due mainly to the uncoating of rough elements. EDTA and PPi shifted slightly the distribution profiles of groups a towards lower densities, possibly as a result of the release of adsorbed proteins. The combination of EDTA and digitonin, used subsequently, rendered the average equilibrium density of group a2 higher than that of groups b and c. Dense subfractions were thus enriched in constituents of group a2 and showed mainly broken-looking vesicles under the electron microscope. The import of our results on the biochemical and enzymic properties of the subcellular components of the microsome fractions is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368410"}
{"pmid": "4368405", "title": "An overview on new procedures in surgery of the hand.", "content": "An overview on new procedures in surgery of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368405"}
{"pmid": "4368412", "title": "Androgen-receptor cycling in prostate cells.", "content": "Androgen-receptor cycling in prostate cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368412"}
{"pmid": "4368413", "title": "Androgens in the human fetus.", "content": "Androgens in the human fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368413"}
{"pmid": "4368414", "title": "Androgens. I. A review of current research on the binding and mechanism of action of androgenic steroids, notably 5 alpha-dihydrotestosterone.", "content": "Androgens. I. A review of current research on the binding and mechanism of action of androgenic steroids, notably 5 alpha-dihydrotestosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368414"}
{"pmid": "4368415", "title": "Animal DNA-dependent RNA polymerases. 10. General enzymatic properties of purified calf thymus RNA polymerases AI and B.", "content": "Animal DNA-dependent RNA polymerases. 10. General enzymatic properties of purified calf thymus RNA polymerases AI and B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368415"}
{"pmid": "4368416", "title": "Anomeric specificity of enzymes of D-glucose metabolism.", "content": "Anomeric specificity of enzymes of D-glucose metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368416"}
{"pmid": "4368417", "title": "Anterior hypophysial function in the posterior-hypophysectomized rat: normal regulation of the adrenal system.", "content": "Anterior hypophysial function in the posterior-hypophysectomized rat: normal regulation of the adrenal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368417"}
{"pmid": "4368418", "title": "Anti-allergic actions of disodium cromoglycate and other drugs known to inhibit cyclic 3',5'-nucleotide phosphodiesterase.", "content": "Anti-allergic actions of disodium cromoglycate and other drugs known to inhibit cyclic 3',5'-nucleotide phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368418"}
{"pmid": "4368421", "title": "Antibodies to Epstein-Barr virus, cytomegalovirus, and Australia antigen in Hodgkin's disease.", "content": "Antibodies to Epstein-Barr virus, cytomegalovirus, and Australia antigen in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368421"}
{"pmid": "4368419", "title": "Antiasthmatic drugs. II. Therapeutic aspects.", "content": "Antiasthmatic drugs. II. Therapeutic aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368419"}
{"pmid": "4368420", "title": "Antibodies to Epstein-Barr and other viruses in children with acute lymphoblastic leukaemia.", "content": "Antibodies to Epstein-Barr and other viruses in children with acute lymphoblastic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368420"}
{"pmid": "4368423", "title": "Anticonvulsant activity and inhibition of respiration in rat brain homogenates by substituted oxadiazoles.", "content": "Anticonvulsant activity and inhibition of respiration in rat brain homogenates by substituted oxadiazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368423"}
{"pmid": "4368422", "title": "Antibody response of susceptible and resistant chickens (type-II leukosis) infected with JM and JM-V leukosis strains and herpesvirus of turkeys (HVT).", "content": "Antibody response of susceptible and resistant chickens (type-II leukosis) infected with JM and JM-V leukosis strains and herpesvirus of turkeys (HVT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368422"}
{"pmid": "4368424", "title": "Appearance of cytotoxic T cells in cerebrospinal fluid of mice with ectromelia virus-induced meningitis.", "content": "Appearance of cytotoxic T cells in cerebrospinal fluid of mice with ectromelia virus-induced meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368424"}
{"pmid": "4368425", "title": "Application of spin-labeled vitamin B6 analogues for the study of aspartate aminotransferase.", "content": "Application of spin-labeled vitamin B6 analogues for the study of aspartate aminotransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368425"}
{"pmid": "4368426", "title": "Applications of kinetic methods to aminoacyl-tRNA synthetases.", "content": "Applications of kinetic methods to aminoacyl-tRNA synthetases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368426"}
{"pmid": "4368427", "title": "Aqueous humour dynamics in ocular hypertension.", "content": "Aqueous humour dynamics in ocular hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368427"}
{"pmid": "4368428", "title": "Arabinose (fucose) dehydrogenase from pig liver. II. Steady-state kinetics.", "content": "Arabinose (fucose) dehydrogenase from pig liver. II. Steady-state kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368428"}
{"pmid": "4368429", "title": "Aromatization of testosterone by human placental microsomes under the presence of sex hormone-binding globulin and 17 beta-estradiol.", "content": "Aromatization of testosterone by human placental microsomes under the presence of sex hormone-binding globulin and 17 beta-estradiol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368429"}
{"pmid": "4368430", "title": "Arrestovisography, a method for objective assessment of visual acuity. Demonstration of the apparatus.", "content": "Arrestovisography, a method for objective assessment of visual acuity. Demonstration of the apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368430"}
{"pmid": "4368431", "title": "Ascorbic acid-like effect of the soluble fraction of rat brain on adenosine triphosphatases and its relation to catecholamines and chelating agents.", "content": "Ascorbic acid-like effect of the soluble fraction of rat brain on adenosine triphosphatases and its relation to catecholamines and chelating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368431"}
{"pmid": "4368432", "title": "Aspects of experimental hepatocarcinogenesis. II. Hyperplastic nodules.", "content": "Aspects of experimental hepatocarcinogenesis. II. Hyperplastic nodules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368432"}
{"pmid": "4368433", "title": "Aspects of the blood-aqueous barrier with special reference to the penetration of antibiotics.", "content": "Aspects of the blood-aqueous barrier with special reference to the penetration of antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368433"}
{"pmid": "4368434", "title": "Association of herpes simplex type 2 virus with cervical cancer of the uterus.", "content": "Association of herpes simplex type 2 virus with cervical cancer of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368434"}
{"pmid": "4368435", "title": "Association of viral and mycoplasma infections with exacerbations of asthma.", "content": "Association of viral and mycoplasma infections with exacerbations of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368435"}
{"pmid": "4368436", "title": "Atypical lymphocytes. Morphologic features.", "content": "Atypical lymphocytes. Morphologic features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368436"}
{"pmid": "4368437", "title": "Automatic determination of the N-terminal sequence of cytochrome C from the insect Ceratitis capitata.", "content": "Automatic determination of the N-terminal sequence of cytochrome C from the insect Ceratitis capitata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368437"}
{"pmid": "4368439", "title": "Autoradiography with a position sensitive counter.", "content": "Autoradiography with a position sensitive counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368439"}
{"pmid": "4368438", "title": "Autoradiographic analysis of gonadotropin binding to rat ovarian tissue sections.", "content": "Autoradiographic analysis of gonadotropin binding to rat ovarian tissue sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368438"}
{"pmid": "4368440", "title": "Availability of zinc in leavened and unleavened wholemeal wheaten breads as measured by solubility and uptake by rat intestine in vitro.", "content": "Availability of zinc in leavened and unleavened wholemeal wheaten breads as measured by solubility and uptake by rat intestine in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368440"}
{"pmid": "4368441", "title": "Axonal degeneration in the sural nerves of cancer patients.", "content": "Axonal degeneration in the sural nerves of cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368441"}
{"pmid": "4368442", "title": "Axonal transport in the retinal ganglion cells of the rabbit under different experimental conditions.", "content": "Axonal transport in the retinal ganglion cells of the rabbit under different experimental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368442"}
{"pmid": "4368443", "title": "ACTH-induced protein release from the perfused cat adrenal gland: evidence for exocytosis?", "content": "ACTH-induced protein release from the perfused cat adrenal gland: evidence for exocytosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368443"}
{"pmid": "4368445", "title": "Bacteriocin susceptibility of Clostridium perfringens: a provisional typing schema.", "content": "Bacteriocin susceptibility of Clostridium perfringens: a provisional typing schema. Ninety-four strains of Clostridium perfringens were examined for bacteriocin production. Bacteriocins produced by ten of these strains were selected for typing 274 cultures of C. perfringens. The bacteriocins were prepared by growing the producer strains in broth and precipitating the active principle from the supernatant fluids of centrifuged cultures with ammonium sulfate. All bacteriocins were titrated against a common indicator strain, adjusted to equivalent titers, and spotted onto blood agar plates seeded with the test organisms. Fifty different bacteriocin sensitivity patterns were observed. These patterns were organized into seven groups bearing some relationship, and the largest number of strains falling into any one pattern did not exceed 16% of the total strains tested. Ninety-nine percent of all isolates were typable. The new method should prove useful in studies where strains must be fingerprinted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368445"}
{"pmid": "4368444", "title": "Bacitracin biosynthesis by three complementary fractions from Bacillus licheniformis.", "content": "Bacitracin biosynthesis by three complementary fractions from Bacillus licheniformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368444"}
{"pmid": "4368446", "title": "Baro- and chemoreceptor mechanisms in haemorrhage.", "content": "Baro- and chemoreceptor mechanisms in haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368446"}
{"pmid": "4368447", "title": "Basis for the selectivity of action of the polymyxin antibiotics on cell membranes.", "content": "Basis for the selectivity of action of the polymyxin antibiotics on cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368447"}
{"pmid": "4368448", "title": "Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.", "content": "Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368448"}
{"pmid": "4368449", "title": "Binding of acetylcholine and cholinergic drugs to proteolipid fractions from rat cerebral cortex and to phospholipids from bovine brain.", "content": "Binding of acetylcholine and cholinergic drugs to proteolipid fractions from rat cerebral cortex and to phospholipids from bovine brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368449"}
{"pmid": "4368450", "title": "Binding of heparin in vitro and in vivo to plasma proteins.", "content": "Binding of heparin in vitro and in vivo to plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368450"}
{"pmid": "4368451", "title": "Binding of thyroid stimulators to thyroid membranes.", "content": "Binding of thyroid stimulators to thyroid membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368451"}
{"pmid": "4368452", "title": "Binding of UGA to wild type and suppressor tryptophan tRNA from E. coli.", "content": "Binding of UGA to wild type and suppressor tryptophan tRNA from E. coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368452"}
{"pmid": "4368453", "title": "Bioassay of oxytocin on the superfused mammary gland of the mouse, using an automatic apparatus.", "content": "Bioassay of oxytocin on the superfused mammary gland of the mouse, using an automatic apparatus. 1 A sensitive method of assaying oxytocin using the superfused mouse mammary gland is described. The method is shown to be reliable, accurate and precise. Assays are performed automatically and the preparation is stable for at least 18 hours.2 The preparation is relatively insensitive to bradykinin, histamine, 5-hydroxytryptamine, angiotensin, prostaglandin F(2alpha), adrenaline and noradrenaline. The contractions produced by acetylcholine can be abolished by atropine without the sensitivity to oxytocin being affected.3 Vasopressin has a variable activity on the preparation; its potency can be as high as one-fifth that of oxytocin.4 It is concluded that this method compares favourably with other published methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368453"}
{"pmid": "4368455", "title": "Biogenic amines and affective disorders.", "content": "Biogenic amines and affective disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368455"}
{"pmid": "4368454", "title": "Biochemical effects of ellipticine on leukemia L1210 cells.", "content": "Biochemical effects of ellipticine on leukemia L1210 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368454"}
{"pmid": "4368456", "title": "Biosynthesis of membrane teichoic acid: role of the D-alanine-activating enzyme and D-alanine: membrane acceptor ligase.", "content": "Biosynthesis of membrane teichoic acid: role of the D-alanine-activating enzyme and D-alanine: membrane acceptor ligase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368456"}
{"pmid": "4368457", "title": "Biosynthesis of valinomycin.", "content": "Biosynthesis of valinomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368457"}
{"pmid": "4368458", "title": "Biosynthesis of water-soluble vitamins.", "content": "Biosynthesis of water-soluble vitamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368458"}
{"pmid": "4368460", "title": "Blood volume of adult germfree and conventional rats.", "content": "Blood volume of adult germfree and conventional rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368460"}
{"pmid": "4368459", "title": "Biosynthesis, physiologic role and normal patterns of lipoproteins in normal human plasma.", "content": "Biosynthesis, physiologic role and normal patterns of lipoproteins in normal human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368459"}
{"pmid": "4368461", "title": "Bluetongue and related viruses in Ibadan, Nigeria: serologic comparison of bluetongue, epizootic hemorrhagic disease of deer, and Abadina (Palyam) viral isolates.", "content": "Bluetongue and related viruses in Ibadan, Nigeria: serologic comparison of bluetongue, epizootic hemorrhagic disease of deer, and Abadina (Palyam) viral isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368461"}
{"pmid": "4368462", "title": "Bluetongue and related viruses in Ibadan, Nigeria: serologic studies of domesticated and wild animals.", "content": "Bluetongue and related viruses in Ibadan, Nigeria: serologic studies of domesticated and wild animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368462"}
{"pmid": "4368463", "title": "Bone marrow and thymus regeneration is a condition for thymoma development.", "content": "Bone marrow and thymus regeneration is a condition for thymoma development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368463"}
{"pmid": "4368464", "title": "Brain stem encephalitic lesions and schizophrenia. A report of 3 cases.", "content": "Brain stem encephalitic lesions and schizophrenia. A report of 3 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368464"}
{"pmid": "4368465", "title": "Calcinosis.", "content": "Calcinosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368465"}
{"pmid": "4368467", "title": "Can benign lymphadenosis (lymphomatosis) of the orbit occasionally be a paraneoplasia?", "content": "Can benign lymphadenosis (lymphomatosis) of the orbit occasionally be a paraneoplasia?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368467"}
{"pmid": "4368466", "title": "Calcium-binding phosphoprotein from pig brain: identification as a calcium-dependent regulator of brain cyclic nucleotide phosphodiesterase.", "content": "Calcium-binding phosphoprotein from pig brain: identification as a calcium-dependent regulator of brain cyclic nucleotide phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368466"}
{"pmid": "4368468", "title": "Canine herpesvirus infection: literature review and case report.", "content": "Canine herpesvirus infection: literature review and case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368468"}
{"pmid": "4368470", "title": "Carbohydrate metabolism in rat uterus during the oestrous cycle.", "content": "Carbohydrate metabolism in rat uterus during the oestrous cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368470"}
{"pmid": "4368471", "title": "Carbohydrate metabolism in shock resistance.", "content": "Carbohydrate metabolism in shock resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368471"}
{"pmid": "4368469", "title": "Canrenoate in normal man.", "content": "Canrenoate in normal man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368469"}
{"pmid": "4368473", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 37-1974.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 37-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368473"}
{"pmid": "4368474", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 38-1974.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 38-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368474"}
{"pmid": "4368475", "title": "Ca2+-induced lateral phase separations in phosphatidic acid-phosphatidylcholine membranes.", "content": "Ca2+-induced lateral phase separations in phosphatidic acid-phosphatidylcholine membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368475"}
{"pmid": "4368476", "title": "Cell fusion by the antigen-antibody complex of Sendai virus studied by electron microscopy.", "content": "Cell fusion by the antigen-antibody complex of Sendai virus studied by electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368476"}
{"pmid": "4368477", "title": "Cell surface glycolipid and glycoprotein glycosyltransferases of normal and transformed cells.", "content": "Cell surface glycolipid and glycoprotein glycosyltransferases of normal and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368477"}
{"pmid": "4368478", "title": "Cell surface immunoglobulin. VI. Dynamics on a human lymphoma line.", "content": "Cell surface immunoglobulin. VI. Dynamics on a human lymphoma line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368478"}
{"pmid": "4368479", "title": "Cell transformation mutants are not susceptible to growth activation by fibroblast growth factor at permissive temperatures.", "content": "Cell transformation mutants are not susceptible to growth activation by fibroblast growth factor at permissive temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368479"}
{"pmid": "4368481", "title": "Central nervous influence upon the adrenocortical reaction during stress situations.", "content": "Central nervous influence upon the adrenocortical reaction during stress situations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368481"}
{"pmid": "4368482", "title": "Cerebral scintigraphy with a Nuclear Chicago 1206 high performance gamma camera.", "content": "Cerebral scintigraphy with a Nuclear Chicago 1206 high performance gamma camera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368482"}
{"pmid": "4368472", "title": "Carcinoma complicating a benign teratoma of the rectum: Report of a case.", "content": "Carcinoma complicating a benign teratoma of the rectum: Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368472"}
{"pmid": "4368483", "title": "Changes in plasma corticosterone and hypothalamic CRF levels following intraventricular injection or drug-induced changes of brain biogenic amines in the rat.", "content": "Changes in plasma corticosterone and hypothalamic CRF levels following intraventricular injection or drug-induced changes of brain biogenic amines in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368483"}
{"pmid": "4368484", "title": "Characteristics of vesicular stomatitis virus envelopes released with saponin.", "content": "Characteristics of vesicular stomatitis virus envelopes released with saponin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368484"}
{"pmid": "4368485", "title": "Characterization of a novel nicotinamide adenine dinucleotide-dependent alcohol dehydrogenase from a strain of Streptococcus mutans.", "content": "Characterization of a novel nicotinamide adenine dinucleotide-dependent alcohol dehydrogenase from a strain of Streptococcus mutans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368485"}
{"pmid": "4368480", "title": "Cellular action of antidiuretic hormone in mice with inherited vasopressin-resistant urinary concentrating defects.", "content": "Cellular action of antidiuretic hormone in mice with inherited vasopressin-resistant urinary concentrating defects. Previous work has suggested that resistance to vasopressin in two strains of mice with nephrogenic deficiency of urinary concentration may entail a defect in the action of vasopressin at the cellular level. Several components involved in this action were therefore examined in vitro in renal medullary tissues from control mice (genotype VII +/+) and two genotypes with mild diabetes insipidus (DI +/+ nonsevere) and marked (DI +/+ severe) vasopressin-resistant concentrating defects. No significant differences were found in the affinity of adenylate cyclase for [8-arginine]-vasopressin (AVP), tested over a range of hormone concentration from 10(-10) to 10(-5) M. However, maximal stimulation of adenylate cyclase by saturating concentrations of AVP (intrinsic activity) was markedly decreased from control values in DI +/+ severe mice, and decreased to a lesser extent in DI +/+ nonsevere animals. A significant correlation was found between the activity of adenylate cyclase maximally stimulated by AVP in a given genotype, and the urine osmolality in the same animals. There were no significant differences in maximal stimulation of renal medullary adenylate cyclase in control experiments: not when stimulated nonspecifically by sodium fluoride, nor when stimulated by AVP in tissues from rats with induced water diuresis as compared to antidiuretic rats. Nor were there significant differences between VII +/+ and DI +/+ severe mice in the activity of renal cortical adenylate cyclase, either basal or when stimulated by parathyroid hormone. Furthermore, the abnormal genotypes did not differ significantly from control mice in the renal medullary activities of cyclic AMP phosphodiesterase or cyclic AMP-dependent protein kinase, nor in the content of microtubular subunits (assessed as colchicinebinding protein). The results are compatible with the view that impaired stimulation of renal medullary adenylate cyclase by vasopressin might be the sole or contributing cause of the vasopressin-resistant concentrating defect in the diseased mice; however, a causal relationship has not yet been proved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368480"}
{"pmid": "4368488", "title": "Characterization of protein kinases forming acid-labile histone phosphates in Walker-256 carcinosarcoma cell nuclei.", "content": "Characterization of protein kinases forming acid-labile histone phosphates in Walker-256 carcinosarcoma cell nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368488"}
{"pmid": "4368486", "title": "Characterization of bromodeoxyuridine-induced endogenous guinea pig virus.", "content": "Characterization of bromodeoxyuridine-induced endogenous guinea pig virus. An endogenous virus (GPV) was induced after 5-bromodeoxyuridine treatment of cultured guinea pig cells. Compared to Gross murine leukemia virus (G-MuLV) GPV has a reproducibly heterogenous density of about 1.16 to 1.18 g/ml. The virion-associated RNA is slightly larger than that in G-MuLV. Sodium dodecyl sulfate-polyacrylamide gel electrophoretic analysis of dissociated GPV resolved five major structural proteins: I (molecular weight 70,000), II (molecular weight 36,000), III (molecular weight 24,000), IV (molecular weight 18,000), and V (molecular weight 16,000) which are similar to but distinct from G-MuLV proteins. Proteins I and II were demonstrated to be glycoproteins by incorporation of [(3)H]glucosamine. GPV and G-MuLV did not have any appreciable genetic homology or any common group-specific antigens when analyzed by immunodiffusion, radioimmunoassay, and indirect immunofluorescence. Morphogenesis of GPV also differed from that of a typical type C oncornavirus and proceeded via two pathways: (i) a majority of virus particles were formed in cytoplasmic vacuoles and were released after cellular disruption; and (ii) a minor population of particles were assembled in the cytoplasmic matrix and then migrated to the plasma membrane where they budded into the extracellular space. To date, GPV has been unable to initiate or maintain a productive replication in any cell line tested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368486"}
{"pmid": "4368487", "title": "Characterization of lactose-fermenting revertants from lactose-negative Streptococcus lactis C2 mutants.", "content": "Characterization of lactose-fermenting revertants from lactose-negative Streptococcus lactis C2 mutants. Partial lactose-fermenting revertants from lactose-negative (lac(-)) mutants of Streptococcus lactis C2 appeared on a lawn of lac(-) cells after 3 to 5 days of incubation at 25 C. The revertants grew slowly on lactose with a growth response similar to that for cryptic cells. In contrast to lac(+)S. lactis C2, the revertants were defective in the accumulation of [(14)C]thiomethyl-beta-d-galactoside, indicating that they were devoid of a transport system. Hydrolysis of o-nitrophenyl-beta-d-galactoside-6-phosphate by toluene-treated cells confirmed the presence of phospho-beta-d-galactosidase (P-beta-gal) in the revertant. However, this enzyme was induced only when the cells were grown in the presence of lactose; galactose was not an inducer. In lac(+)S. lactis C2, enzyme induction occurred in lactose- or galactose-grown cells. The revertants were defective in EII-lactose and FIII-lactose of the phosphoenolpyruvate-dependent phosphotransferase system. Galactokinase activity was detected in cell extracts of lac(+)S. lactis C2, but the activity was 9 to 13 times higher in extracts from the revertant and lac(-), respectively. This suggested that the lac(-) and the revertants use the Leloir pathway for galactose metabolism and that galactose-1-phosphate rather than galactose-6-phosphate was being formed. This may explain why lactose, but not galactose, induced P-beta-gal in the revertants. Because the revertant was unable to form galactose-6-phosphate, induction could not occur. This compound would be formed on hydrolysis of lactose phosphate. The data also indicate that galactose-6-phosphate may serve not only as an inducer of the lactose genes in S. lactis C2, but also as a repressor of the Leloir pathway for galactose metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368487"}
{"pmid": "4368489", "title": "Characterization of slowly interconvertible states of phosphoribosyladenosine triphosphate synthetase dependent on temperature, substrates, and histidine.", "content": "Characterization of slowly interconvertible states of phosphoribosyladenosine triphosphate synthetase dependent on temperature, substrates, and histidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368489"}
{"pmid": "4368491", "title": "Chemical and physico-chemical alterations of human erythrocytes by periodate, succinic anhydride, 2-phenylethanol, and 1,1-dimethylphenylethanol: effects on membrane permeability and on metabolism of intact cells and hemolysates.", "content": "Chemical and physico-chemical alterations of human erythrocytes by periodate, succinic anhydride, 2-phenylethanol, and 1,1-dimethylphenylethanol: effects on membrane permeability and on metabolism of intact cells and hemolysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368491"}
{"pmid": "4368490", "title": "Chemical and biological evolution of nucleotide-binding protein.", "content": "Chemical and biological evolution of nucleotide-binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368490"}
{"pmid": "4368492", "title": "Chemical determination of oestrogen distribution in the foetus and placenta of the domestic pig.", "content": "Chemical determination of oestrogen distribution in the foetus and placenta of the domestic pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368492"}
{"pmid": "4368493", "title": "Chemotherapy in intraocular metastasis from carcinoma of the breast.", "content": "Chemotherapy in intraocular metastasis from carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368493"}
{"pmid": "4368494", "title": "Children's mental health services: a case study of a successful grant proposal.", "content": "Children's mental health services: a case study of a successful grant proposal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368494"}
{"pmid": "4368495", "title": "Chinese hamster hypoxanthine-guanine phosphoribosyltransferase. Purification, structural, and catalytic properties.", "content": "Chinese hamster hypoxanthine-guanine phosphoribosyltransferase. Purification, structural, and catalytic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368495"}
{"pmid": "4368496", "title": "Chloroquine-induced ultrastructural changes in the pigment epithelium of the albino rat.", "content": "Chloroquine-induced ultrastructural changes in the pigment epithelium of the albino rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368496"}
{"pmid": "4368497", "title": "Cholangiofibrosis induced by short-term feeding of 3'-methyl-4-(dimethylamino)azobenzene: an electron microscopic observation.", "content": "Cholangiofibrosis induced by short-term feeding of 3'-methyl-4-(dimethylamino)azobenzene: an electron microscopic observation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368497"}
{"pmid": "4368498", "title": "Cholinergic stimulation of phospholipid labelling from (32P) orthophosphate in guinea-pig cortex synaptosomes in vitro: subsynaptosomal localization.", "content": "Cholinergic stimulation of phospholipid labelling from (32P) orthophosphate in guinea-pig cortex synaptosomes in vitro: subsynaptosomal localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368498"}
{"pmid": "4368500", "title": "Chromatographic changes in specific tRNAs after reaction with cyanogen bromide and sodium periodate.", "content": "Chromatographic changes in specific tRNAs after reaction with cyanogen bromide and sodium periodate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368500"}
{"pmid": "4368499", "title": "Chromatin-associated DNA endonuclease activities in HeLa cells.", "content": "Chromatin-associated DNA endonuclease activities in HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368499"}
{"pmid": "4368502", "title": "Chronic cyclitis in children.", "content": "Chronic cyclitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368502"}
{"pmid": "4368504", "title": "Circular dichroism spectra of DNA of high adenine plus thymine content.", "content": "Circular dichroism spectra of DNA of high adenine plus thymine content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368504"}
{"pmid": "4368503", "title": "Circular dichroism of DNA in the vacuum ultraviolet.", "content": "Circular dichroism of DNA in the vacuum ultraviolet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368503"}
{"pmid": "4368505", "title": "Cleavage of 23-S RNA in 50-S ribosomes into a 5'-terminal and a 3'-terminal fragment by pancreatic ribonuclease.", "content": "Cleavage of 23-S RNA in 50-S ribosomes into a 5'-terminal and a 3'-terminal fragment by pancreatic ribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368505"}
{"pmid": "4368506", "title": "Clinical and pathological effects of streptozotocin.", "content": "Clinical and pathological effects of streptozotocin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368506"}
{"pmid": "4368508", "title": "Clinical evaluation of endolymphatic radiotherapy in malignant lymphoma.", "content": "Clinical evaluation of endolymphatic radiotherapy in malignant lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368508"}
{"pmid": "4368509", "title": "Clinical immunology and the physician. Blood.", "content": "Clinical immunology and the physician. Blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368509"}
{"pmid": "4368501", "title": "Chronic aggressive hepatitis. Report of a case with virus like particles in the liver.", "content": "Chronic aggressive hepatitis. Report of a case with virus like particles in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368501"}
{"pmid": "4368510", "title": "Clinical significance of circulating hormonal substances.", "content": "Clinical significance of circulating hormonal substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368510"}
{"pmid": "4368512", "title": "Cold agglutinin production and cytomegalovirus infection.", "content": "Cold agglutinin production and cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368512"}
{"pmid": "4368511", "title": "Clusters in lipid bilayers and the interpretation of thermal effects in biological membranes.", "content": "Clusters in lipid bilayers and the interpretation of thermal effects in biological membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368511"}
{"pmid": "4368514", "title": "Collagenases (first of three parts).", "content": "Collagenases (first of three parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368514"}
{"pmid": "4368515", "title": "Collagenases (second of three parts).", "content": "Collagenases (second of three parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368515"}
{"pmid": "4368516", "title": "Collagenases (third of three parts).", "content": "Collagenases (third of three parts).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368516"}
{"pmid": "4368518", "title": "Comparative effects of prostaglandins A2 and B2 on vascular and airway resistances and adrenergic neurotransmission.", "content": "Comparative effects of prostaglandins A2 and B2 on vascular and airway resistances and adrenergic neurotransmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368518"}
{"pmid": "4368517", "title": "Combined use of 99mtechnetium-labelled macroaggregates of albumin and 75selenium-selenomethionine in the diagnosis of lung cancer.", "content": "Combined use of 99mtechnetium-labelled macroaggregates of albumin and 75selenium-selenomethionine in the diagnosis of lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368517"}
{"pmid": "4368507", "title": "Clinical disorders of sleep.", "content": "Clinical disorders of sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368507"}
{"pmid": "4368520", "title": "Comparison between different techniques of immuno-protection in the A-SW mouse-SEWA tumour system.", "content": "Comparison between different techniques of immuno-protection in the A-SW mouse-SEWA tumour system. Various procedures for immunoprotection in the A-SW mouse SEWA tumour system were compared. Four types of protector agents were used: polyoma virus, allogeneic S724 cells, A9/SEWA hybrid cells and xenogeneic ST(py) cells. Several injection schedules were also employed. On the whole, reasonable immunoprotection was obtained. The results, when allogeneic hybrid or xenogeneic cells were used, were comparable with those obtained for polyoma virus. This indicates that the T.A.T.A. of the SEWA tumour had been well conserved. When polyoma virus alone was used as the protector agent, injection 7 days before the tumour challenge, or iterative injection, afforded better protection than a single injection on the day of challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368520"}
{"pmid": "4368521", "title": "Comparison between the effect of luteinizing hormone and prostaglandin E1 on ovarian cyclic AMP.", "content": "Comparison between the effect of luteinizing hormone and prostaglandin E1 on ovarian cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368521"}
{"pmid": "4368513", "title": "Colitis cystica profunda, an unusual solitary tumor: Report of three cases.", "content": "Colitis cystica profunda, an unusual solitary tumor: Report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368513"}
{"pmid": "4368522", "title": "Comparison of actions of papaverine, aspaminol and isoprenaline on isolated rat uterus.", "content": "Comparison of actions of papaverine, aspaminol and isoprenaline on isolated rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368522"}
{"pmid": "4368523", "title": "Comparison of analysis of isoniazid and its dosage forms by several methods.", "content": "Comparison of analysis of isoniazid and its dosage forms by several methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368523"}
{"pmid": "4368524", "title": "Comparison of immunoglobulin formation in vitro by leukocytes of normal donors and steroid- and nonsteroid-treated asthmatic patients.", "content": "Comparison of immunoglobulin formation in vitro by leukocytes of normal donors and steroid- and nonsteroid-treated asthmatic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368524"}
{"pmid": "4368525", "title": "Comparison of somatic mutation rates induced in Tradescantia by chemical and physical mutagens.", "content": "Comparison of somatic mutation rates induced in Tradescantia by chemical and physical mutagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368525"}
{"pmid": "4368527", "title": "Comparison of the properties of glucosaminephosphate isomerase (glutamine-forming) from rat liver and a hepatoma.", "content": "Comparison of the properties of glucosaminephosphate isomerase (glutamine-forming) from rat liver and a hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368527"}
{"pmid": "4368528", "title": "Compartmentalization of murein hydrolases in the envelope of Escherichia coli.", "content": "Compartmentalization of murein hydrolases in the envelope of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368528"}
{"pmid": "4368526", "title": "Comparison of the presynaptic actions of botulinum toxin and beta-bungarotoxin on neuromuscular transmission.", "content": "Comparison of the presynaptic actions of botulinum toxin and beta-bungarotoxin on neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368526"}
{"pmid": "4368519", "title": "Comparative studies on mitochondrial development in yeasts. 3. Growth-phasic effects of antibiotics on mitochondrial differentiation in Candida.", "content": "Comparative studies on mitochondrial development in yeasts. 3. Growth-phasic effects of antibiotics on mitochondrial differentiation in Candida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368519"}
{"pmid": "4368529", "title": "Concentration of amino acids in aqueous humour and plasma in congenital cataract or dislocation of the lens.", "content": "Concentration of amino acids in aqueous humour and plasma in congenital cataract or dislocation of the lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368529"}
{"pmid": "4368530", "title": "Conformation changes in cytochrome c2 from Rhodospirillum rubrum.", "content": "Conformation changes in cytochrome c2 from Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368530"}
{"pmid": "4368531", "title": "Conformation of cyclic beta-adenosine 3',5'-phosphate in solution using the lanthanide shift technique.", "content": "Conformation of cyclic beta-adenosine 3',5'-phosphate in solution using the lanthanide shift technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368531"}
{"pmid": "4368532", "title": "Conformational differences in myosin. Evidence for change in rate limiting step of the magnesium stimulated ITPase of myosin.", "content": "Conformational differences in myosin. Evidence for change in rate limiting step of the magnesium stimulated ITPase of myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368532"}
{"pmid": "4368534", "title": "Consideration of potential parasite food hazards.", "content": "Consideration of potential parasite food hazards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368534"}
{"pmid": "4368533", "title": "Conjugated estrogen therapy and tests of thyroid function.", "content": "Conjugated estrogen therapy and tests of thyroid function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368533"}
{"pmid": "4368535", "title": "Constant occurrence of adrenocortical tissue in the juvenile rabbit ovary.", "content": "Constant occurrence of adrenocortical tissue in the juvenile rabbit ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368535"}
{"pmid": "4368536", "title": "Control of membrane lipid fluidity in Acholeplasma laidlawii.", "content": "Control of membrane lipid fluidity in Acholeplasma laidlawii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368536"}
{"pmid": "4368538", "title": "Corneal reflection of a straight line and ophthalmometry in normal people and in asymptomatic relatives of patients with keratoconus. A preliminary report.", "content": "Corneal reflection of a straight line and ophthalmometry in normal people and in asymptomatic relatives of patients with keratoconus. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368538"}
{"pmid": "4368537", "title": "Copper deficiency in the developing rat brain: a possible model for Menkes' steely-hair disease.", "content": "Copper deficiency in the developing rat brain: a possible model for Menkes' steely-hair disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368537"}
{"pmid": "4368539", "title": "Cortisol induction of glycerol phosphate dehydrogenase in a rat brain tumour cell line.", "content": "Cortisol induction of glycerol phosphate dehydrogenase in a rat brain tumour cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368539"}
{"pmid": "4368540", "title": "Cross-pathway regulation: histidine-mediated control of histidine, tryptophan, and arginine biosynthetic enzymes in Neurospora crassa.", "content": "Cross-pathway regulation: histidine-mediated control of histidine, tryptophan, and arginine biosynthetic enzymes in Neurospora crassa. In Neurospora crassa, histidine starvation of histidine mutants resulted in derepression of histidine, tryptophan, and arginine biosynthetic enzymes. The same tripartite derepression occurred in wild-type strain 74A when it was grown in medium supplemented with 3-amino-1,2,4-triazole, an inhibitor of histidine biosynthesis. Histidine-mediated derepression of tryptophan and arginine biosynthetic enzymes was not due to a lowered intracellular concentration of tryptophan or arginine, respectively. A discussion of possible mechanisms and of similar studies in prokaryotic and eukaryotic organisms is presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368540"}
{"pmid": "4368542", "title": "Cryptic A-like receptor sites in human erythrocyte glycoproteins: proposed nature of Tn-antigen.", "content": "Cryptic A-like receptor sites in human erythrocyte glycoproteins: proposed nature of Tn-antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368542"}
{"pmid": "4368543", "title": "Cultivation of Entamoeba histolytica with bacterial associates. Isolation and maintenance of Taiwan strains.", "content": "Cultivation of Entamoeba histolytica with bacterial associates. Isolation and maintenance of Taiwan strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368543"}
{"pmid": "4368541", "title": "Cross-pathway regulation: tryptophan-mediated control of histidine and arginine biosynthetic enzymes in Neurospora crassa.", "content": "Cross-pathway regulation: tryptophan-mediated control of histidine and arginine biosynthetic enzymes in Neurospora crassa. In Neurospora crassa, the starvation of tryptophan mutants for tryptophan resulted in the derepression of tryptophan, histidine, and arginine biosynthetic enzymes. This tryptophan-mediated derepression of histidine and arginine biosynthetic enzymes occurred despite the fact that the tryptophan-starved cells had a higher intracellular concentration of histidine and arginine than did nonstarved cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368541"}
{"pmid": "4368544", "title": "Cutting the REM nerve: an approach to the adaptive role of REM sleep.", "content": "Cutting the REM nerve: an approach to the adaptive role of REM sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368544"}
{"pmid": "4368545", "title": "Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli.", "content": "Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli. The major limitation to our understanding of the clinical importance of enterotoxigenic Escherichia coli in diarrheal illness has been the lack of a simple rapid assay for the enterotoxin produced by certain E. coli. On the basis of the activation of adenylate cyclase by heat-labile enterotoxin of E. coli (LT) and by cholera toxin (CT) in intestinal and other tissues, cultured Chinese hamster ovary (CHO) cells with known morphological responses to dibutyryl cyclic adenosine 5'-monophosphate (AMP) were exposed to these enterotoxins. Crude culture filtrates of LT-producing E. coli and CT stimulated cyclic AMP accumulation and cell elongation in CHO cells. The similarity of time course, concentration dependence, and potentiation by phosphodiesterase inhibitors suggested cyclic AMP mediation of the morphological change. Heat inactivated CT and LT in this system. Choleragenoid inhibited CT; antiserum against CT inhibited both enterotoxin effects. In contrast to culture filtrates of 16 strains of E. coli known to produce LT, culture filtrates from 13 E. coli that do not produce LT did not alter CHO cell morphology. The morphological change is a simple, specific assay for these enterotoxins and detect 3 x 10(-17) mol of CT or a 1:250 dilution of crude culture filtrate of LT-producing E. coli 334.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368545"}
{"pmid": "4368546", "title": "Cyclic adenosine 3':5'-monophosphate metabolism in normal and SV40-transformed WI-38 cells.", "content": "Cyclic adenosine 3':5'-monophosphate metabolism in normal and SV40-transformed WI-38 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368546"}
{"pmid": "4368547", "title": "Cyclic guanosine 3':5'-monophosphate in Escherichia coli and Bacillus lichenformis.", "content": "Cyclic guanosine 3':5'-monophosphate in Escherichia coli and Bacillus lichenformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368547"}
{"pmid": "4368548", "title": "Cyclic guanosine-3':5'-monophosphate induced diuresis in rats.", "content": "Cyclic guanosine-3':5'-monophosphate induced diuresis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368548"}
{"pmid": "4368550", "title": "Cyclic nucleotides in higher plants?", "content": "Cyclic nucleotides in higher plants?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368550"}
{"pmid": "4368549", "title": "Cyclic nucleotide levels during spontaneous uterine contractions.", "content": "Cyclic nucleotide levels during spontaneous uterine contractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368549"}
{"pmid": "4368552", "title": "Cyclic AMP and the immune response;.", "content": "Cyclic AMP and the immune response;.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368552"}
{"pmid": "4368553", "title": "Cyclic AMP and the transformation of fibroblasts.", "content": "Cyclic AMP and the transformation of fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368553"}
{"pmid": "4368554", "title": "Cyclic AMP and the triggering of the decidual reaction.", "content": "Cyclic AMP and the triggering of the decidual reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368554"}
{"pmid": "4368556", "title": "Cytochalasin B: aspects of phagocytosis in nutrient uptake in Tetrahymena.", "content": "Cytochalasin B: aspects of phagocytosis in nutrient uptake in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368556"}
{"pmid": "4368555", "title": "Cytarabine treatment of progressive multifocal leukoencephalopathy. Clinical course and detection of virus-like particles after antiviral chemotherapy.", "content": "Cytarabine treatment of progressive multifocal leukoencephalopathy. Clinical course and detection of virus-like particles after antiviral chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368555"}
{"pmid": "4368557", "title": "Cytochrome c peroxidase catalyzed oxidation of ferrocyanide by hydrogen peroxide. Steady-state kinetics.", "content": "Cytochrome c peroxidase catalyzed oxidation of ferrocyanide by hydrogen peroxide. Steady-state kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368557"}
{"pmid": "4368558", "title": "Cytochrome c peroxidase catalyzed oxidation of ferrocyanide by hydrogen peroxide. Transient state kinetics.", "content": "Cytochrome c peroxidase catalyzed oxidation of ferrocyanide by hydrogen peroxide. Transient state kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368558"}
{"pmid": "4368559", "title": "Cytochrome c: a thermodynamic study of the relationship among oxidation state, ion-binding and structural parameters. Cation binding to horse-heart ferrocytochrome c.", "content": "Cytochrome c: a thermodynamic study of the relationship among oxidation state, ion-binding and structural parameters. Cation binding to horse-heart ferrocytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368559"}
{"pmid": "4368560", "title": "Cytochrome P450 associated with free hepatic polyribosomes.", "content": "Cytochrome P450 associated with free hepatic polyribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368560"}
{"pmid": "4368561", "title": "Cytosol-binding protein of thyroxine and triiodothyronine in human and rat kidney tissue.", "content": "Cytosol-binding protein of thyroxine and triiodothyronine in human and rat kidney tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368561"}
{"pmid": "4368562", "title": "D(-)-beta-hydroxybutyrate dehydrogenase activity in cloned cell lines of glial and neuronal origin.", "content": "D(-)-beta-hydroxybutyrate dehydrogenase activity in cloned cell lines of glial and neuronal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368562"}
{"pmid": "4368564", "title": "Demodicosis in the Mongolian gerbil (Meriones unguiculatus): a case report.", "content": "Demodicosis in the Mongolian gerbil (Meriones unguiculatus): a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368564"}
{"pmid": "4368565", "title": "Demonstration of alpha-Fetoglobulin in hepatoma tissue by fluorescent antibody technique.", "content": "Demonstration of alpha-Fetoglobulin in hepatoma tissue by fluorescent antibody technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368565"}
{"pmid": "4368566", "title": "Demonstration of protease-like activity in human serum low density lipoprotein.", "content": "Demonstration of protease-like activity in human serum low density lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368566"}
{"pmid": "4368551", "title": "Cyclic AMP and anxiety.", "content": "Cyclic AMP and anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368551"}
{"pmid": "4368568", "title": "Deoxyglucose transport changes in murine sarcoma virus-infected cells-a quantitative assay for virus transforming activity.", "content": "Deoxyglucose transport changes in murine sarcoma virus-infected cells-a quantitative assay for virus transforming activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368568"}
{"pmid": "4368570", "title": "Design consideration for long-acting antagonists.", "content": "Design consideration for long-acting antagonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368570"}
{"pmid": "4368569", "title": "Deoxyribonucleic acid-dependent ribonucleic acid polymerase activity in purified Chlamydia trachomatis initial bodies.", "content": "Deoxyribonucleic acid-dependent ribonucleic acid polymerase activity in purified Chlamydia trachomatis initial bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368569"}
{"pmid": "4368571", "title": "Detection of antibodies against virally-induced tumor-associated antigens by mixed hemadsorption.", "content": "Detection of antibodies against virally-induced tumor-associated antigens by mixed hemadsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368571"}
{"pmid": "4368572", "title": "Detection of cardiac damage using a steady state assay for lactate dehydrogenase isoenzymes in serum.", "content": "Detection of cardiac damage using a steady state assay for lactate dehydrogenase isoenzymes in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368572"}
{"pmid": "4368563", "title": "Death and dying--oncology discussion group.", "content": "Death and dying--oncology discussion group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368563"}
{"pmid": "4368573", "title": "Detection of tumor-virus associated antibodies by mixed hemadsorption.", "content": "Detection of tumor-virus associated antibodies by mixed hemadsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368573"}
{"pmid": "4368575", "title": "Determination of glycerol dehydratase activity by the coupled enzymic method.", "content": "Determination of glycerol dehydratase activity by the coupled enzymic method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368575"}
{"pmid": "4368574", "title": "Detection of Epstein-Barr virus (EBV)-associated nuclear antigen in human lymphoblastoid cell lines by means of an 125-I-IgG-binding assay.", "content": "Detection of Epstein-Barr virus (EBV)-associated nuclear antigen in human lymphoblastoid cell lines by means of an 125-I-IgG-binding assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368574"}
{"pmid": "4368576", "title": "Determination of the absolute hand of the helix in the nucleocapsid of haemagglutinating virus (Japan).", "content": "Determination of the absolute hand of the helix in the nucleocapsid of haemagglutinating virus (Japan).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368576"}
{"pmid": "4368577", "title": "Determination of the age of some anopheline mosquitos by daily growth layers of skeletal apodemes.", "content": "Determination of the age of some anopheline mosquitos by daily growth layers of skeletal apodemes. Earlier work has shown that it is possible to determine the calendar age of Culex and Aedes mosquitos by counting the daily layers of cuticular growth on the inner apodemes. In view of the epidemiological importance of age grouping in Anopheles species, the applicability of the method to this genus was studied in both laboratory-reared and field-collected specimens. In the four species examined, it was found possible to distinguish daily growth layers for periods of up to 10-13 days provided that proper staining procedures are used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368577"}
{"pmid": "4368567", "title": "Density changes in herpesvirus-infected cells.", "content": "Density changes in herpesvirus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368567"}
{"pmid": "4368578", "title": "Determination of the catalytically active unit of fructose 1,6-diphosphatase from rabbit liver.", "content": "Determination of the catalytically active unit of fructose 1,6-diphosphatase from rabbit liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368578"}
{"pmid": "4368579", "title": "Determination of the vanadium content of protein solutions by electron paramagnetic resonance spectroscopy.", "content": "Determination of the vanadium content of protein solutions by electron paramagnetic resonance spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368579"}
{"pmid": "4368580", "title": "Development of an inexpensive cell culture medium for the production of foot-and-mouth disease vaccine.", "content": "Development of an inexpensive cell culture medium for the production of foot-and-mouth disease vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368580"}
{"pmid": "4368582", "title": "Development of Periplaneta americana (L.) cell cultures and their infection with enteroviruses.", "content": "Development of Periplaneta americana (L.) cell cultures and their infection with enteroviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368582"}
{"pmid": "4368581", "title": "Development of methods for detecting viruses in solid waste landfill leachates.", "content": "Development of methods for detecting viruses in solid waste landfill leachates. Methods were developed for detecting and concentrating enteric viruses in municipal solid waste landfill leachates. Poliovirus added to a leachate was not readily detectable, possibly because the virus was adsorbed to the leachate particulates. The masking effects associated with suspended solids in the leachate were overcome by adding a final 0.1 M sodium (tetra)ethylenediaminetetraacetate concentration to the leachate. A sodium (tetra)ethylenediaminetetraacetate-treated leachate could be clarified by filtration at pH 8.0 without a loss of virus. The clarified and sodium (tetra)ethylenediaminetetraacetate-treated leachate contained interfering materials of an anionic nature which prevented virus adsorption to epoxy-fiber glass filters. This interfering effect was overcome by treating the leachate with an anion-exchange resin. Viruses in the resin-treated leachate were concentrated by adjusting the leachate to pH 3.5, adding AlCl(3) to a final 0.005 M concentration, adsorbing the viruses to an epoxy-fiber glass virus adsorbent, and eluting the adsorbed viruses in a small volume. When this method was used to concentrate poliovirus 100-fold in a variety of leachates, the average virus recovery efficiency was 37%. With the methods described in this study, it should be possible to efficiently monitor solid waste disposal site leachates for enteric viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368581"}
{"pmid": "4368583", "title": "Developmental changes of steryl esters in normal and jimpy mouse brain.", "content": "Developmental changes of steryl esters in normal and jimpy mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368583"}
{"pmid": "4368584", "title": "Developments in monitoring human populations for mutation rates.", "content": "Developments in monitoring human populations for mutation rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368584"}
{"pmid": "4368585", "title": "Diagnosis of recent Herpes simplex infections. A modified immunofluorescent test for the detection of specific Herpes simplex IgM antibodies after staphylococcal adsorption of IgG.", "content": "Diagnosis of recent Herpes simplex infections. A modified immunofluorescent test for the detection of specific Herpes simplex IgM antibodies after staphylococcal adsorption of IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368585"}
{"pmid": "4368586", "title": "Dielectric measurements of Nitellopsis obtusa cells with intracellular electrodes.", "content": "Dielectric measurements of Nitellopsis obtusa cells with intracellular electrodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368586"}
{"pmid": "4368587", "title": "Differential effects of Mg2+ on various hydrolytic and synthetic activities of multifunctional glucose-6-phosphatase.", "content": "Differential effects of Mg2+ on various hydrolytic and synthetic activities of multifunctional glucose-6-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368587"}
{"pmid": "4368588", "title": "Differential properties of prostaglandin and gonadotropin receptors in the bovine corpus lutuem cell membranes.", "content": "Differential properties of prostaglandin and gonadotropin receptors in the bovine corpus lutuem cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368588"}
{"pmid": "4368590", "title": "Differentiation of type A foot-and-mouth disease virus subtypes by double- and radial-immunodiffusion analysis.", "content": "Differentiation of type A foot-and-mouth disease virus subtypes by double- and radial-immunodiffusion analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368590"}
{"pmid": "4368589", "title": "Differential spermatogenic response of mice to the induction of mutations by antineoplastic drugs.", "content": "Differential spermatogenic response of mice to the induction of mutations by antineoplastic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368589"}
{"pmid": "4368591", "title": "Diguanosinetetraphosphate guanylohydrolase in Artemia salina.", "content": "Diguanosinetetraphosphate guanylohydrolase in Artemia salina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368591"}
{"pmid": "4368592", "title": "Diphenylhydantoin treatment of glycogen storage diseases.", "content": "Diphenylhydantoin treatment of glycogen storage diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368592"}
{"pmid": "4368593", "title": "Distribution and some properties of acid phosphatase in the 7,12-dimethylbenz(alpha) anthracene-induced rat-mammary carcinoma.", "content": "Distribution and some properties of acid phosphatase in the 7,12-dimethylbenz(alpha) anthracene-induced rat-mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368593"}
{"pmid": "4368594", "title": "Disturbances of the hypothalamo-hypophysial-adrenocortical system in the alloxan diabetic rat.", "content": "Disturbances of the hypothalamo-hypophysial-adrenocortical system in the alloxan diabetic rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368594"}
{"pmid": "4368595", "title": "Divergent synaptic influences affecting discharge patterning of genioglossus motor units.", "content": "Divergent synaptic influences affecting discharge patterning of genioglossus motor units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368595"}
{"pmid": "4368596", "title": "Dopamine-beta-hydroxylase activity in cholinergic neuroblastoma times glioma hybrid cells; increase of activity by N6,O2'-dibutyryl adenosine 3':5'-cyclic monophosphate.", "content": "Dopamine-beta-hydroxylase activity in cholinergic neuroblastoma times glioma hybrid cells; increase of activity by N6,O2'-dibutyryl adenosine 3':5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368596"}
{"pmid": "4368597", "title": "Dopamine-induced inhibition of synaptic transmission in the inferior mesenteric ganglion of the dog.", "content": "Dopamine-induced inhibition of synaptic transmission in the inferior mesenteric ganglion of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368597"}
{"pmid": "4368598", "title": "Dose response analysis of 0.1 per cent, 0.5 per cent, 1.0 per cent, and 2.0 per cent epinephrine in chronic open-angle glaucoma.", "content": "Dose response analysis of 0.1 per cent, 0.5 per cent, 1.0 per cent, and 2.0 per cent epinephrine in chronic open-angle glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368598"}
{"pmid": "4368600", "title": "Duck viral enteritis: microtiter plate isolation and neutralization test using the duck embryo fibroblast cell line.", "content": "Duck viral enteritis: microtiter plate isolation and neutralization test using the duck embryo fibroblast cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368600"}
{"pmid": "4368599", "title": "Drinking induced by injections of angiotensin into forebrain and mid-brain sites of the monkey.", "content": "Drinking induced by injections of angiotensin into forebrain and mid-brain sites of the monkey. 1. Unilateral and bilateral injections of 1.0 mul. solutions of angiotensin II into specific brain sites produced copious drinking of water in the water-replete rhesus monkey (Macaca mulatta).2. Of six brain regions in seven monkeys into which a total of 368 microinjections of angiotensin II were made, three were sensitive to angiotensin II. In decreasing order of sensitivity, they were (i) a rostral zone that included the septum, the anterior hypothalamus and the preoptic region, (ii) a caudal zone consisting of the mesencephalic central grey, and (iii) the lateral and third ventricles near the foramen of Monro. Of the regions tested, those that were relatively inactive included (i) the mid line thalmus, (ii) the mid-brain reticular formation, and (iii) metencephalic points in the cerebellum, the 4th ventricle and the dorsal aspect of the pons.3. Bilateral microinjections of angiotensin II into the sensitive regions in doses as low as 0.75-6 ng were dipsogenic and, with increasing doses, drinking occurred in a dose-dependent fashion up to 500 ng, after which the amount drunk levelled off or was reduced. The dose-response curve for unilateral microinjections began at 12.5 ng, and at doses higher than 50 ng unilateral and bilateral microinjections were equipotent.4. The onset of drinking (without eating) averaged 2.1-3.2 min following the end of microinjections for all sensitive tissue sites. Injections into the ventricles produced significantly longer drinking latencies.5. Angiotensin I elicited drinking in amounts comparable to angiotensin II at a dose of 100 ng whereas analogues of angiotensin II were weak dipsogens. Of the three analogues tested, Phe(4), Tyr(8)-angiotensin II was the most potent dipsogen, followed by Ile(8)-angiotensin II. The 1-7 heptapeptide, des-Phe(8)-angiotensin II was an ineffective dipsogen. Carbachol microinjected into the most sensitive angiotensin drinking sites had no dipsogenic action in the water-replete monkey.6. Tachyphylaxis to angiotensin II was demonstrated as a reduction in mean water intake of 55 and 74 per cent on the second and third microinjections, respectively. This reduction appeared to be due to dilutional inhibition or signals from the amount of water ingested on the first microinjection of angiotensin II.7. Monkeys drank an amount equal to a normal daily intake following two to three microinjections of angiotensin II in doses of 100-250 ng into sensitive regions. This extra water load caused no reductions in normal daily water intake either for the remainder of the experimental day or 24 hr later.8. Pre-treatments with microinjections of an angiotensin-converting enzyme inhibitor, SQ 20,881, did not reduce the dipsogenic action of angiotensin I, suggesting that this and perhaps other peptide precursors act directly on receptor mechanisms to produce drinking. Attempts to change the polydipsic effects of angiotensin II were unsuccessful with pre-treatments of intracranial microinjections of either haloperidol, Ile(8)-angiotensin II or carbachol.9. Microinjections of angiotensin II dissolved in hypertonic saline solutions had no influence on water intake when compared with the same dose dissolved in distilled water or isotonic saline.10. Yawning was the only other response that appeared to be related directly to intracranial injections of angiotensin II. In some instances, a hyperactive state of the animal followed intraventricular injections of angiotensin II. In other instances, intracranial microinjections of angiotensin II were followed by quietude or e.e.g. and behavioural signs of light sleep.11. This work further confirms the findings of previous research which showed that angiotensin II is the most potent dipsogen in all species tested to date. This endogenous peptide appears to participate in natural thirst by acting on central mechanisms of extracellular thirst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368599"}
{"pmid": "4368601", "title": "Duodenal calcium binding protein in the chick: a new bioassay for vitamin D.", "content": "Duodenal calcium binding protein in the chick: a new bioassay for vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368601"}
{"pmid": "4368602", "title": "Dynamics of cyclic adenosine 3',5'-monophosphate release during adrenocortical stimulation in vivo.", "content": "Dynamics of cyclic adenosine 3',5'-monophosphate release during adrenocortical stimulation in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368602"}
{"pmid": "4368603", "title": "Dyskeratotic marginal keratoconjunctivitis in hereditary periodontopathy and hyperkeratosis.", "content": "Dyskeratotic marginal keratoconjunctivitis in hereditary periodontopathy and hyperkeratosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368603"}
{"pmid": "4368604", "title": "Dyslipoproteinemias and diabetes mellitus.", "content": "Dyslipoproteinemias and diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368604"}
{"pmid": "4368605", "title": "Ecological survey by the immunofluorescent method of virus in enzootics of avian encephalomyelitis.", "content": "Ecological survey by the immunofluorescent method of virus in enzootics of avian encephalomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368605"}
{"pmid": "4368606", "title": "Editorial: Burkitt's lymphoma;.", "content": "Editorial: Burkitt's lymphoma;.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368606"}
{"pmid": "4368607", "title": "Editorial: New concepts in adipose tissue metabolism and obesity.", "content": "Editorial: New concepts in adipose tissue metabolism and obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368607"}
{"pmid": "4368608", "title": "Editorial: The endogenous factor in intestinal calcium absorption.", "content": "Editorial: The endogenous factor in intestinal calcium absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368608"}
{"pmid": "4368609", "title": "Effect of aging on renal membrane-bound enzyme activities.", "content": "Effect of aging on renal membrane-bound enzyme activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368609"}
{"pmid": "4368610", "title": "Effect of carbachol on amino acid incorporation into protein of rat pancreas in vitro.", "content": "Effect of carbachol on amino acid incorporation into protein of rat pancreas in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368610"}
{"pmid": "4368611", "title": "Effect of chemical mediators on the K+-efflux, Ca2+-uptake and 32P-incorporation of erythrocytes.", "content": "Effect of chemical mediators on the K+-efflux, Ca2+-uptake and 32P-incorporation of erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368611"}
{"pmid": "4368612", "title": "Effect of chloroquine on acid phosphatase activity in the pigment epithelium of the retina of albino and pigmented rats.", "content": "Effect of chloroquine on acid phosphatase activity in the pigment epithelium of the retina of albino and pigmented rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368612"}
{"pmid": "4368613", "title": "Effect of chlorpropamide on cyclic AMP in rat renal medulla.", "content": "Effect of chlorpropamide on cyclic AMP in rat renal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368613"}
{"pmid": "4368614", "title": "Effect of cyclopentolate on the aqueous dynamics in incipient or suspected open-angle glaucoma.", "content": "Effect of cyclopentolate on the aqueous dynamics in incipient or suspected open-angle glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368614"}
{"pmid": "4368615", "title": "Effect of cyclophosphamide on ACTH-induced kidney disease.", "content": "Effect of cyclophosphamide on ACTH-induced kidney disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368615"}
{"pmid": "4368616", "title": "Effect of drugs on the activity of thrombocytes 3,5-cyclic AMP phosphodiesterase.", "content": "Effect of drugs on the activity of thrombocytes 3,5-cyclic AMP phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368616"}
{"pmid": "4368617", "title": "Effect of estradiol on lipolysis and adenosine 3',5'-monophosphate accumulation in isolated rat adipocytes.", "content": "Effect of estradiol on lipolysis and adenosine 3',5'-monophosphate accumulation in isolated rat adipocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368617"}
{"pmid": "4368618", "title": "Effect of extracellular chondroitin sulfate on cultured chondrocytes.", "content": "Effect of extracellular chondroitin sulfate on cultured chondrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368618"}
{"pmid": "4368619", "title": "Effect of flavin adenine dinucleotide on the glucose-6-phosphate dehydrogenase activity of adrenal gland of hypophysectomized rats.", "content": "Effect of flavin adenine dinucleotide on the glucose-6-phosphate dehydrogenase activity of adrenal gland of hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368619"}
{"pmid": "4368620", "title": "Effect of fusidic acid on sporulation of Bacillus subtilis.", "content": "Effect of fusidic acid on sporulation of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368620"}
{"pmid": "4368621", "title": "Effect of glucagon, epinephrine, cyclic 3',5'-AMP, N6-2'-0-dibutyryl cyclic 3',5'-AMP and insulin upon the phosphate exchange of the isolated perfused fed rat liver.", "content": "Effect of glucagon, epinephrine, cyclic 3',5'-AMP, N6-2'-0-dibutyryl cyclic 3',5'-AMP and insulin upon the phosphate exchange of the isolated perfused fed rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368621"}
{"pmid": "4368622", "title": "Effect of glycine and serine in synthetic amino acid diets upon glycine and serine metabolism in chicks.", "content": "Effect of glycine and serine in synthetic amino acid diets upon glycine and serine metabolism in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368622"}
{"pmid": "4368623", "title": "Effect of hypervitaminosis A on the testes of the rat during lactation.", "content": "Effect of hypervitaminosis A on the testes of the rat during lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368623"}
{"pmid": "4368625", "title": "Effect of induced hypothyroidism on pituitary luteinizing hormone (LH) concentration in female rats.", "content": "Effect of induced hypothyroidism on pituitary luteinizing hormone (LH) concentration in female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368625"}
{"pmid": "4368624", "title": "Effect of immunisation with heat-killed micro-organisms on transplantation immunity to adenovirus-12-induced tumour cells.", "content": "Effect of immunisation with heat-killed micro-organisms on transplantation immunity to adenovirus-12-induced tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368624"}
{"pmid": "4368627", "title": "Effect of isoproterenol on blood pressure, plasma renin activity, and water intake in rats.", "content": "Effect of isoproterenol on blood pressure, plasma renin activity, and water intake in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368627"}
{"pmid": "4368626", "title": "Effect of inhibitors of ribonucleic acid and protein synthesis on the cyclic adenosine monophosphate stimulation of plasmid ColE1 replication.", "content": "Effect of inhibitors of ribonucleic acid and protein synthesis on the cyclic adenosine monophosphate stimulation of plasmid ColE1 replication. Addition of cyclic adenosine 3'-5'-monophosphate (c-AMP) to growing Escherichia coli cells, colicinogenic for the plasmid ColE1, results in a fourfold stimulation in the rate of synthesis of the plasmid deoxyribonucleic acid (DNA). The stimulation is transient (30 min) and is succeeded by a brief period (30 min) of cessation of plasmid DNA replication. The stimulation of ColE1 DNA replication also occurs in chloramphenicol-treated cells. Rifampin inhibits ColE1 DNA replication in the presence or absence of c-AMP. Employing thymine starvation conditions to stop ColE1 DNA synthesis, it was found that c-AMP, added during the period of thymine starvation, effected a stimulation in the amount of subsequent replication which took place when replicating conditions were restored. The stimulatory effect of c-AMP under these conditions was not prevented by chloramphenicol but was completely eliminated when rifampin was present. Under these conditions, when rifampin was added after the effect of c-AMP was allowed to occur, subsequent replication of the plasmid could take place, but only one round of replication occurred. A model to account for the c-AMP effects is presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368626"}
{"pmid": "4368628", "title": "Effect of paracentesis on ocular antibiotic concentration.", "content": "Effect of paracentesis on ocular antibiotic concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368628"}
{"pmid": "4368629", "title": "Effect of phenformin on lipid transport in hypertriglyceridemia.", "content": "Effect of phenformin on lipid transport in hypertriglyceridemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368629"}
{"pmid": "4368630", "title": "Effect of phospholipase C on the permeability of the toad bladder.", "content": "Effect of phospholipase C on the permeability of the toad bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368630"}
{"pmid": "4368631", "title": "Effect of potassium sorbate on salmonellae, Staphylococcus aureus, Clostridium perfringens, and Clostridium botulinum in cooked, uncured sausage.", "content": "Effect of potassium sorbate on salmonellae, Staphylococcus aureus, Clostridium perfringens, and Clostridium botulinum in cooked, uncured sausage. Skinless precooked, uncured sausage links with and without potassium sorbate (0.1% wt/wt) were inoculated with salmonellae, Staphylococcus aureus, Clostridium perfringens, and Clostridium botulinum and held at 27 C to represent temperature abuse of the product. Total counts of uninoculated product showed that the normal spoilage flora was delayed 1 day when sorbate was present. Growth of salmonellae was markedly retarded by sorbate. Growth of S. aureus was delayed 1 day in the presence of sorbate, after which growth occurred to the same level as in product without sorbate. C. perfringens declined to below detectable levels within the first day in product with and without sorbate. Sorbate retarded the growth of C. botulinum. Botulinal toxin was detected in 4 days in product without sorbate but not until after 10 days in product with sorbate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368631"}
{"pmid": "4368633", "title": "Effect of short-term increased intraocular pressure on the fine structure of the retina.", "content": "Effect of short-term increased intraocular pressure on the fine structure of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368633"}
{"pmid": "4368632", "title": "Effect of schistosomal infection and of schistosomicidal drugs on the drug metabolizing enzymes of mouse liver.", "content": "Effect of schistosomal infection and of schistosomicidal drugs on the drug metabolizing enzymes of mouse liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368632"}
{"pmid": "4368634", "title": "Effect of somatostatin on glucose induced insulin release in isolated perfused rat pancreas and isolated rat pancreatic islets.", "content": "Effect of somatostatin on glucose induced insulin release in isolated perfused rat pancreas and isolated rat pancreatic islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368634"}
{"pmid": "4368636", "title": "Effect of vasoconstrictors on lymph oxygen tension in normo- and hypovolemia.", "content": "Effect of vasoconstrictors on lymph oxygen tension in normo- and hypovolemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368636"}
{"pmid": "4368635", "title": "Effect of stretching on the elastic characteristics and the contractile component of frog striated muscle.", "content": "Effect of stretching on the elastic characteristics and the contractile component of frog striated muscle. 1. The force-velocity relationship and the stress-strain curve of the so-called series elastic component (s.e.c.) of frog sartorius, semitendinosus and gastrocnemius have been determined during shortening against a given force (isotonic quick-release) and at high speed (controlled release): (a) from a state of isometric contraction and (b) after stretching of the contracted muscle. In both cases the muscle was released from the same length: this was usually slightly greater than the muscle's resting length.2. The muscle released immediately after being stretched is able to shorten against a constant force, P, equal to or even greater than the isometric force, P(0), at the same length. When the force P applied to the muscle is reduced below P(0) the velocity of shortening is greater after stretching, and the force-velocity curve is therefore shifted along the velocity axis: the shift is maximal when P is near to P(0) and it decreases rapidly with decreasing P.3. The extent of shortening of the s.e.c. required to make the force fall from P(0) to zero is 50-100% greater when the muscle is released immediately after stretching than when it is released from a state of isometric contraction. This difference is found by using either the controlled release method or the isotonic quick-release method.4. If a time interval is left between the end of stretching and the onset of shortening of the contracted muscle (controlled release method), the length change of the s.e.c., for a given fall of the force, is reduced and approaches that taking place when the muscle is released from a state of isometric contraction.5. Curare does not affect the results described above, indicating that these do not depend on modification of the neuromuscular transmission.6. It is concluded that stretching a contracted muscle modifies temporarily: (a) its elastic characteristics, as shown by the greater amount of mechanical energy released for a given fall of the force at the muscle's extremities, and (b) its contractile machinery, as it is suggested by the change of the force-velocity relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368635"}
{"pmid": "4368637", "title": "Effect of DB-c-AMP on mechanical characteristics of ventricular and atrial preparations of several mammalian species.", "content": "Effect of DB-c-AMP on mechanical characteristics of ventricular and atrial preparations of several mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368637"}
{"pmid": "4368638", "title": "Effect of 2'-deoxythymidine on experimental herpes infection.", "content": "Effect of 2'-deoxythymidine on experimental herpes infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368638"}
{"pmid": "4368639", "title": "Effect on growth and structure of transplantable malignant melanomas of the Syrian golden hamster (Mesocricetus auratus) by depletion of phenylalanine and tyrosine in the diet and by inhibition of tyrosinase. Brief report.", "content": "Effect on growth and structure of transplantable malignant melanomas of the Syrian golden hamster (Mesocricetus auratus) by depletion of phenylalanine and tyrosine in the diet and by inhibition of tyrosinase. Brief report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368639"}
{"pmid": "4368640", "title": "Effects of acetylcholine on incorporation of (14C)glucose into phosphatidylinositol and on phosphatidylinositol breakdown in subcellular fractions from cerebral cortex.", "content": "Effects of acetylcholine on incorporation of (14C)glucose into phosphatidylinositol and on phosphatidylinositol breakdown in subcellular fractions from cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368640"}
{"pmid": "4368641", "title": "Effects of adrenalectomy and corticosterone on thyroid weight of goitrogen-treated rats. Role of adrenal-corticoids in the insulin increase of goitre weight.", "content": "Effects of adrenalectomy and corticosterone on thyroid weight of goitrogen-treated rats. Role of adrenal-corticoids in the insulin increase of goitre weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368641"}
{"pmid": "4368642", "title": "Effects of alcohols on the autoxidation of cytochrome c-1.", "content": "Effects of alcohols on the autoxidation of cytochrome c-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368642"}
{"pmid": "4368643", "title": "Effects of cyclic adenosine nucleotides on fluid absorption by different segments of proximal tubule.", "content": "Effects of cyclic adenosine nucleotides on fluid absorption by different segments of proximal tubule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368643"}
{"pmid": "4368645", "title": "Effects of dopamine-like drugs on rat striatal adenyl cyclase have implications for CNS dopamine receptor topography.", "content": "Effects of dopamine-like drugs on rat striatal adenyl cyclase have implications for CNS dopamine receptor topography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368645"}
{"pmid": "4368644", "title": "Effects of demethylchlortetracycline on cellular action of antidiuretic hormone in vitro.", "content": "Effects of demethylchlortetracycline on cellular action of antidiuretic hormone in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368644"}
{"pmid": "4368646", "title": "Effects of ethanol, methanol and different antibiotics on the ATPase and GTPase activities associated with B. stearothermophilus 5 S RNS- protein complex.", "content": "Effects of ethanol, methanol and different antibiotics on the ATPase and GTPase activities associated with B. stearothermophilus 5 S RNS- protein complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368646"}
{"pmid": "4368647", "title": "Effects of halothane and other anesthetic agents on the concentrations of rat liver metabolites in vivo.", "content": "Effects of halothane and other anesthetic agents on the concentrations of rat liver metabolites in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368647"}
{"pmid": "4368648", "title": "Effects of hypophysectomy and TSH replacement on the ultrastructural localization of thyroperoxidase.", "content": "Effects of hypophysectomy and TSH replacement on the ultrastructural localization of thyroperoxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368648"}
{"pmid": "4368650", "title": "Effects of ovine luteinizing hormone and porcine adrenocorticotropin on maturation of oocytes of the catfish, Heteropneustes fossilis (Bloch), in ovary-interrenal coculture.", "content": "Effects of ovine luteinizing hormone and porcine adrenocorticotropin on maturation of oocytes of the catfish, Heteropneustes fossilis (Bloch), in ovary-interrenal coculture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368650"}
{"pmid": "4368649", "title": "Effects of morphine on kinetics of 14C-dopamine in rat striatal slices.", "content": "Effects of morphine on kinetics of 14C-dopamine in rat striatal slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368649"}
{"pmid": "4368651", "title": "Effects of photo-oxidation on the catalytic and regulatory properties of citrate synthase from Acinetobacter lwoffi.", "content": "Effects of photo-oxidation on the catalytic and regulatory properties of citrate synthase from Acinetobacter lwoffi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368651"}
{"pmid": "4368652", "title": "Effects of pyrazole on ethanol-induced changes in hepatic triglyceride and glycerol-1-phosphate contents and on esterified and non-esterified fatty acids in the blood.", "content": "Effects of pyrazole on ethanol-induced changes in hepatic triglyceride and glycerol-1-phosphate contents and on esterified and non-esterified fatty acids in the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368652"}
{"pmid": "4368653", "title": "Effects of succinyl-con A on the growth of normal and transformed cells.", "content": "Effects of succinyl-con A on the growth of normal and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368653"}
{"pmid": "4368654", "title": "Effects of theophylline and propranolol on acetylcholine-induced release of adrenal medullary catecholamines.", "content": "Effects of theophylline and propranolol on acetylcholine-induced release of adrenal medullary catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368654"}
{"pmid": "4368655", "title": "Effects of thyroid hormone deficiency on cyclic adenosine 3':5'-monophosphate and control of lipolysis in fat cells.", "content": "Effects of thyroid hormone deficiency on cyclic adenosine 3':5'-monophosphate and control of lipolysis in fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368655"}
{"pmid": "4368656", "title": "Effects of ACTH on the sleep of normal subjects and patients with Addison's disease.", "content": "Effects of ACTH on the sleep of normal subjects and patients with Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368656"}
{"pmid": "4368657", "title": "Electro-oculography: a clinical normal case series.", "content": "Electro-oculography: a clinical normal case series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368657"}
{"pmid": "4368659", "title": "Electrocorticogram and behavioral correlates during the development of chronic cobalt experimental epilepsy in the rat.", "content": "Electrocorticogram and behavioral correlates during the development of chronic cobalt experimental epilepsy in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368659"}
{"pmid": "4368661", "title": "Electron microscopical studies of the acetylcholinesterase-positive and -negative nerve fibres in the ciliary body of the albino rat.", "content": "Electron microscopical studies of the acetylcholinesterase-positive and -negative nerve fibres in the ciliary body of the albino rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368661"}
{"pmid": "4368658", "title": "Electro-optical system for monitoring activity of heart cells in culture: application to the study of several drugs and scorpion toxins.", "content": "Electro-optical system for monitoring activity of heart cells in culture: application to the study of several drugs and scorpion toxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368658"}
{"pmid": "4368660", "title": "Electron microscopic observations on postnatal development of the X zone in mouse adrenal cortex.", "content": "Electron microscopic observations on postnatal development of the X zone in mouse adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368660"}
{"pmid": "4368662", "title": "Electron microscopy as a supplement in the diagnosis of glomus jugulare tumor.", "content": "Electron microscopy as a supplement in the diagnosis of glomus jugulare tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368662"}
{"pmid": "4368663", "title": "Electron microscopy of the lung in experimental Toxocara canis infection.", "content": "Electron microscopy of the lung in experimental Toxocara canis infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368663"}
{"pmid": "4368666", "title": "Electron spin resonance spectrometry on the whole mouse in vivo: a 100 MHZ spectrometer.", "content": "Electron spin resonance spectrometry on the whole mouse in vivo: a 100 MHZ spectrometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368666"}
{"pmid": "4368665", "title": "Electron paramagnetic resonance study of the interaction of a spin-labeled analog of adenosine diphosphoribose with paramagnetic cobalt(II) liver alcohol dehydrogenase.", "content": "Electron paramagnetic resonance study of the interaction of a spin-labeled analog of adenosine diphosphoribose with paramagnetic cobalt(II) liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368665"}
{"pmid": "4368664", "title": "Electron microscopy of young Candida albicans chlamydospores.", "content": "Electron microscopy of young Candida albicans chlamydospores. One- to three-day-old cultures of Candida albicans bearing chlamydospores were grown and harvested by a special technique, free of agar, and prepared for ultramicrotomy and electron microscopy. These young chlamydospores exhibited a subcellular structure similar to that of the yeast phase, e.g., cytoplasmic membrane, ribosomes, and mitochondria. Other structural characteristics unique to chlamydospores were a very thick, layered cell wall, the outer layer of which was continuous with the outer layer of the suspensor cell wall and was covered by hair-like projections; membrane bound organelles; and large lipoid inclusions. Only young chlamydospores less than 3 to 4 days old exhibited these ultrastructural characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368664"}
{"pmid": "4368667", "title": "Electron spin resonance studies of free radicals in solution. 3. pH dependence of thiyl free radical of cysteine.", "content": "Electron spin resonance studies of free radicals in solution. 3. pH dependence of thiyl free radical of cysteine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368667"}
{"pmid": "4368668", "title": "Electron spin resonance studies on diol dehydrase. 3. Rapid kinetic studies on the rate of formation of radicals in the reaction with propanediol.", "content": "Electron spin resonance studies on diol dehydrase. 3. Rapid kinetic studies on the rate of formation of radicals in the reaction with propanediol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368668"}
{"pmid": "4368669", "title": "Electron transport phosphorylation.", "content": "Electron transport phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368669"}
{"pmid": "4368670", "title": "Electron-paramagnetic-resonance studies on nitrogenase. Investigation of the oxidation-reduction behaviour of azoferredoxin and molybdoferredoxin with potentiometric and rapid-freeze techniques.", "content": "Electron-paramagnetic-resonance studies on nitrogenase. Investigation of the oxidation-reduction behaviour of azoferredoxin and molybdoferredoxin with potentiometric and rapid-freeze techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368670"}
{"pmid": "4368671", "title": "Electron-paramagnetic-resonance study of manganese ions bound to concanavalin A.", "content": "Electron-paramagnetic-resonance study of manganese ions bound to concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368671"}
{"pmid": "4368672", "title": "Elongation factor T-dependent GTP hydrolysis: dissociation from aminoacyl-tRNA binding.", "content": "Elongation factor T-dependent GTP hydrolysis: dissociation from aminoacyl-tRNA binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368672"}
{"pmid": "4368673", "title": "Elongation factor 2. Amino acid sequence at the site of adenosine diphosphate ribosylation.", "content": "Elongation factor 2. Amino acid sequence at the site of adenosine diphosphate ribosylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368673"}
{"pmid": "4368674", "title": "Encephalomyocarditis virus infection of mouse plasmacytoma cells. I. Inhibition of cellular protein synthesis.", "content": "Encephalomyocarditis virus infection of mouse plasmacytoma cells. I. Inhibition of cellular protein synthesis. Mouse plasmacytoma ascites tumor cells (MOPC 460) were efficiently infected with encephalomyocarditis virus. Inhibition of host protein synthesis was evident after 2 h and complete by 4 h postinfection. The mechanism by which virus infection results in inhibition of host cell protein synthesis was studied in vitro. Cell-free protein-synthesizing systems, prepared from uninfected and infected cells, were found to be equally active with respect to their abilities to translate cellular and viral mRNAs. The plasmacytoma cell-free system was also shown to be insensitive to the addition of double-stranded viral RNA. Host cellular mRNA was isolated from uninfected and infected cells. No difference in the amount or size distribution of the mRNA was detected. However, the mRNA from infected cells was translated only 46 to 49% as actively as that from uninfected cells. mRNA isolated from cells in which initiation of protein synthesis was inhibited with pactamycin was similarly inactivated. Simultaneous addition of viral RNA and cellular mRNA to the plasmacytoma cell-free system resulted in a complete suppression of the translation of the cellular message, whereas viral RNA was translated normally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368674"}
{"pmid": "4368676", "title": "Endemic goitre and thyroid function in Central Africa.", "content": "Endemic goitre and thyroid function in Central Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368676"}
{"pmid": "4368677", "title": "Endocrine functions during adaptation to stress.", "content": "Endocrine functions during adaptation to stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368677"}
{"pmid": "4368675", "title": "Encephalomyocarditis virus infection of mouse plasmacytoma cells. II. Effect on host RNA synthesis and RNA polymerases.", "content": "Encephalomyocarditis virus infection of mouse plasmacytoma cells. II. Effect on host RNA synthesis and RNA polymerases. The effect of encephalomyocarditis virus infection of MOPC 460 mouse plasmacytoma cells on host RNA synthesis and RNA polymerases was investigated. Consistent with work performed in other virus host systems, rates of RNA synthesis appeared to be inhibited in infected cells, whereas RNA degradation appeared normal. These results were further extended with isolated nuclei, in which distinct RNA polymerase activities could be studied under conditions where problems with RNA turnover and endogenous nucleotide pool sizes were insignificant. Endogenous nuclear RNA polymerase II activity was inhibited early postinfection and at 1 to 2 h prior to endogenous RNA polymerase I plus III activity. However, the solubilized enzymes were fully active with exogenous DNA as template. In fact, the levels of RNA polymerases I, II, and III, isolated from infected cells and nuclei, were indistinguishable from levels in uninfected cells and nuclei at each stage of their partial purification procedure. The chromatographic properties of the enzymes on DEAE-Sephadex were also unaltered. Furthermore, the RNA synthetic activity of these isolated enyzmes, or of nuclei isolated from uninfected cells, was resistant to extracts of nuclei or of cytoplasmic fractions from infected cells. These results are discussed in terms of a possible inhibition of RNA synthesis in vivo at the level of transcription initiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368675"}
{"pmid": "4368679", "title": "Enhanced interferon response to murine leukemia virus by ascorbic acid.", "content": "Enhanced interferon response to murine leukemia virus by ascorbic acid. BALB/cJ mice, on an ad libitum regimen of 250 mg% l-ascorbate in their drinking water, displayed augmented levels of circulating interferon after stimulation with murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368679"}
{"pmid": "4368681", "title": "Enhancement of radiation effects by heating of the tumor.", "content": "Enhancement of radiation effects by heating of the tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368681"}
{"pmid": "4368680", "title": "Enhancement of radiation effects by chemotherapy.", "content": "Enhancement of radiation effects by chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368680"}
{"pmid": "4368682", "title": "Enhancement of DNA synthesis of mouse myelogenous cells by cyclic adenosine 3',5'-monophosphate (cAMP).", "content": "Enhancement of DNA synthesis of mouse myelogenous cells by cyclic adenosine 3',5'-monophosphate (cAMP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368682"}
{"pmid": "4368683", "title": "Enterovirus type 70: the etiologic agent of pandemic acute haemorrhagic conjunctivitis.", "content": "Enterovirus type 70: the etiologic agent of pandemic acute haemorrhagic conjunctivitis. A new enterovirus, now classified as enterovirus type 70, was isolated from the conjunctiva of patients with acute haemorrhagic conjunctivitis during the 1971 epidemics that occurred in Japan, Singapore, and Morocco. These epidemics were parts of a pandemic involving Africa (Algeria, Ghana, Morocco, Nigeria, and Tunisia), Asia (Cambodia, China (Province of Taiwan), Hong Kong, India, Indonesia, Japan, Malaysia, the Philippines, Singapore, and Thailand), and England during 1969-71. A representative strain from each of the three epidemic areas was studied cooperatively. The strains exhibited the physicochemical characteristics of enteroviruses. Cross-neutralization tests showed that these viruses were distinct from all known human enterovirus immunotypes, but that they were antigenically closely related. The human origin of the viruses was demonstrated by the appearance of homologous neutralizing antibodies during convalescence in patients with acute haemorrhagic conjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368683"}
{"pmid": "4368684", "title": "Environmental mutagen testing in Escherichia coli and phage lambda.", "content": "Environmental mutagen testing in Escherichia coli and phage lambda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368684"}
{"pmid": "4368685", "title": "Enzymatic acylation of 1-alkyl-, 1-alkenyl- and 1-acyl glycero-3-phosphorylethanolamine in developing rat brain.", "content": "Enzymatic acylation of 1-alkyl-, 1-alkenyl- and 1-acyl glycero-3-phosphorylethanolamine in developing rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368685"}
{"pmid": "4368686", "title": "Enzymatic formation of uridine diphosphate N-acetyl-D-mannosaminuronic acid.", "content": "Enzymatic formation of uridine diphosphate N-acetyl-D-mannosaminuronic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368686"}
{"pmid": "4368678", "title": "Endocrine tumors of the pancreas associated with elevated urinary serotonin excretion.", "content": "Endocrine tumors of the pancreas associated with elevated urinary serotonin excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368678"}
{"pmid": "4368687", "title": "Enzymatic methods for sequence analysis applied to DNA restriction and methylation sites.", "content": "Enzymatic methods for sequence analysis applied to DNA restriction and methylation sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368687"}
{"pmid": "4368689", "title": "Epinephrine binding by rat liver plasma membranes: effect of guanyl nucleotides.", "content": "Epinephrine binding by rat liver plasma membranes: effect of guanyl nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368689"}
{"pmid": "4368688", "title": "Epidermal growth factor: effects of androgens and adrenergic agents.", "content": "Epidermal growth factor: effects of androgens and adrenergic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368688"}
{"pmid": "4368690", "title": "Epstein-Barr virus and heterophile antibodies in infectious mononucleosis.", "content": "Epstein-Barr virus and heterophile antibodies in infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368690"}
{"pmid": "4368691", "title": "Epstein-Barr virus specific diagnostic tests in infectious mononucleosis.", "content": "Epstein-Barr virus specific diagnostic tests in infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368691"}
{"pmid": "4368692", "title": "Equilibrium kinetic study of bovine liver glutamate dehydrogenase at high pH.", "content": "Equilibrium kinetic study of bovine liver glutamate dehydrogenase at high pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368692"}
{"pmid": "4368693", "title": "Erythrocyte membrane vacuole formation in hereditary spherocytosis.", "content": "Erythrocyte membrane vacuole formation in hereditary spherocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368693"}
{"pmid": "4368694", "title": "Escape of intestinal resistance vessels to angiotensin II.", "content": "Escape of intestinal resistance vessels to angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368694"}
{"pmid": "4368697", "title": "Estradiol receptors: a new evaluation.", "content": "Estradiol receptors: a new evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368697"}
{"pmid": "4368695", "title": "Escape of TA3 tumors from allogeneic immune rejection: theory and experiments.", "content": "Escape of TA3 tumors from allogeneic immune rejection: theory and experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368695"}
{"pmid": "4368696", "title": "Establishment of a tetraploid, immunoglobulin-producing cell line from the hybridization of two human lymphocyte lines.", "content": "Establishment of a tetraploid, immunoglobulin-producing cell line from the hybridization of two human lymphocyte lines. We here report the establishment of a seemingly permanent hybrid cell line formed by fusion of the cells of two biochemically mutant human lymphocyte lines. One parental line (UM-1-6TGr) was deficient in hypoxanthine-guanine phosphoribosyl transferase (IMP: pyrophosphate phosphoribosyltransferase, EC 2.4.2.8), and had two marker chromosomes. The second parental line (UM-21-5) was a clonal derivative of a citrullinemic lymphocyte line, and was, like the line of origin, dificient in argininosuccinic acid synthetase [(L)-Citrulline: (L)-aspartate ligase (AMP-forming), EC 6.3.4.5]. This line also had a marker chromosome, which was a B5 with a very prominent secondary constriction. After trypsinization of both parental lines, followed by addition to the fusion mixture of beta-propiolactone-inactivated Sendai virus, the cells were placed in a doubly selective medium (hypoxanthine-aminopterin-thymidine-containing medium in which the arginine was replaced with citrulline) to prevent the proliferation of the mutant parents. Under selective conditions, 97-99% of cells were found to be tetraploid, containing the three marker chromosomes; and the specific activities of the hybrid line transferase and synthetase were intermediate between normal and mutant line values. Furthermore, the UM-1-6TGr and UM-21-5 lines were producers of gamma and mu heavy chains of immunoglobulin, and of kappa light chains, as determined by immunodiffusion and immunofluorescence, and the hybrid line continued to synthesize and to secrete detectable levels of these same immunoglobulins. These studies demonstrate the genic and cytogenetic stability of this hybridized lymphocyte cell line, and prove that hybridization per se does not extinguish the activity of either the regulatory of structural genes involved in immunoglobulin synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368696"}
{"pmid": "4368698", "title": "Estrogen binding in the rat and human.", "content": "Estrogen binding in the rat and human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368698"}
{"pmid": "4368699", "title": "Estrogen receptor transformation and nuclear RNA synthesis.", "content": "Estrogen receptor transformation and nuclear RNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368699"}
{"pmid": "4368700", "title": "Estrogenic profile on a water-soluble estrogen, estrazinol hydrobromide.", "content": "Estrogenic profile on a water-soluble estrogen, estrazinol hydrobromide. The estrogenic properties of estrazinol hydrobromide (EZ), a water-soluble estrogen, were compared with those of Premarin (PR), another water-soluble estrogen preparation consisting of conjugated equine estrogens.  Estradiol-17beta, estra-1,3,5(10)-triene-3,17beta-diol (E), and ethinyl estradiol, 17alpha-ethinyl-1,3,5 (10)-estratriene-3,17beta-diol (EE) were used as reference standards.  Subcutaneous progesterone (400 mcg) given to rabbits primed with comparable subcutaneous doses of either E or EE produced full secretory changes of the endometrium, while such a transformation could not be elicited in orally primed animals  regardless of the estrogen used.  The biological profile or orally administered EZ was very similar to that of oral EE and different from oral PR.  Howerver, the oral EZ-induced morphological changes of the rabbit endometrium appeared somewhat different from those produced by oral EE.  The findings indicated that following oral administration, EZ-induced endometrial transformation is more \"normal\" and/or adequate than the changes produced by either EE or PR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368700"}
{"pmid": "4368701", "title": "Ethanol-induced inhibition of human intestinal enzyme activities: reversal by folic acid.", "content": "Ethanol-induced inhibition of human intestinal enzyme activities: reversal by folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368701"}
{"pmid": "4368702", "title": "Evaluation of physical maturity in adolescent mentally retarded boys.", "content": "Evaluation of physical maturity in adolescent mentally retarded boys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368702"}
{"pmid": "4368703", "title": "Evidence against formation of a pyrophosphoryl enzyme intermediate in the phosphoribosylpyrophosphate synthetase reaction.", "content": "Evidence against formation of a pyrophosphoryl enzyme intermediate in the phosphoribosylpyrophosphate synthetase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368703"}
{"pmid": "4368705", "title": "Evidence for a role for protein phosphorylation in synaptic function in the cerebral cortex mediated through a beta noradrenergic receptor.", "content": "Evidence for a role for protein phosphorylation in synaptic function in the cerebral cortex mediated through a beta noradrenergic receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368705"}
{"pmid": "4368704", "title": "Evidence for a guanosine-3':5'-monophosphate-binding protein from rat cerebellum.", "content": "Evidence for a guanosine-3':5'-monophosphate-binding protein from rat cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368704"}
{"pmid": "4368706", "title": "Evidence for a role of the Epstein-Barr virus in the etiology of human lymphoma.", "content": "Evidence for a role of the Epstein-Barr virus in the etiology of human lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368706"}
{"pmid": "4368707", "title": "Evidence for cooperative binding of Triton X-100 to bovine serum albumin.", "content": "Evidence for cooperative binding of Triton X-100 to bovine serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368707"}
{"pmid": "4368708", "title": "Evolutionary clock: the rate of evolution of rattlesnake cytochrome c.", "content": "Evolutionary clock: the rate of evolution of rattlesnake cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368708"}
{"pmid": "4368709", "title": "Existence of two pools of prostaglandins during stimulation of the thyroid by TSH.", "content": "Existence of two pools of prostaglandins during stimulation of the thyroid by TSH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368709"}
{"pmid": "4368710", "title": "Experimental autoallergic parotitis.", "content": "Experimental autoallergic parotitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368710"}
{"pmid": "4368711", "title": "Experimental transmission of equine adenovirus in Arabian and non-Arabian foals.", "content": "Experimental transmission of equine adenovirus in Arabian and non-Arabian foals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368711"}
{"pmid": "4368714", "title": "Facial muscle tonus during REM and NREM sleep.", "content": "Facial muscle tonus during REM and NREM sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368714"}
{"pmid": "4368712", "title": "Extraction, partial purification and characterization of 'the insoluble estrogen receptor' from chick liver nuclei.", "content": "Extraction, partial purification and characterization of 'the insoluble estrogen receptor' from chick liver nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368712"}
{"pmid": "4368713", "title": "EM49: a new polypeptide antibiotic active against cell membranes.", "content": "EM49: a new polypeptide antibiotic active against cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368713"}
{"pmid": "4368716", "title": "Factors affecting the saturation assay of cyclic AMP in biological systems.", "content": "Factors affecting the saturation assay of cyclic AMP in biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368716"}
{"pmid": "4368717", "title": "Factors associated with treatment success in lithium carbonate prophylaxis. Report of the Veterans Administration and National Institute of Mental Health collaborative study group.", "content": "Factors associated with treatment success in lithium carbonate prophylaxis. Report of the Veterans Administration and National Institute of Mental Health collaborative study group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368717"}
{"pmid": "4368715", "title": "Facilitation by adenosine of the action of insulin on the accumulation of adenosine 3':5'-monophosphate, lipolysis, and glucose oxidation in isolated fat cells.", "content": "Facilitation by adenosine of the action of insulin on the accumulation of adenosine 3':5'-monophosphate, lipolysis, and glucose oxidation in isolated fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368715"}
{"pmid": "4368718", "title": "Failure of pentagastrin to stimulate cyclic AMP accumulation in human gastric mucosa.", "content": "Failure of pentagastrin to stimulate cyclic AMP accumulation in human gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368718"}
{"pmid": "4368719", "title": "False negative and prozone reactions in tests for antibodies to Epstein-Barr virus-associated nuclear antigen.", "content": "False negative and prozone reactions in tests for antibodies to Epstein-Barr virus-associated nuclear antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368719"}
{"pmid": "4368720", "title": "Familial homozygous hypobetalipoproteinemia.", "content": "Familial homozygous hypobetalipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368720"}
{"pmid": "4368721", "title": "Fatal adenovirus pneumonia in a young adult associated with ADV-7 vaccine administered 15 days earlier.", "content": "Fatal adenovirus pneumonia in a young adult associated with ADV-7 vaccine administered 15 days earlier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368721"}
{"pmid": "4368722", "title": "Fatty acid composition of the major lipid classes of very low density lipoproteins and of plasma in rats poisoned with carbon tetrachloride.", "content": "Fatty acid composition of the major lipid classes of very low density lipoproteins and of plasma in rats poisoned with carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368722"}
{"pmid": "4368724", "title": "Feed preferences of adult male Dutch rabbits.", "content": "Feed preferences of adult male Dutch rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368724"}
{"pmid": "4368723", "title": "Fc binding of IgG to skeletal muscle tissue.", "content": "Fc binding of IgG to skeletal muscle tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368723"}
{"pmid": "4368725", "title": "Feeding in ciliated protozoa. I. Pharyngeal disks in Euplotes: a source of membrane for food vacuole formation?", "content": "Feeding in ciliated protozoa. I. Pharyngeal disks in Euplotes: a source of membrane for food vacuole formation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368725"}
{"pmid": "4368726", "title": "Fibrinolysis associated with oncogenic transformation. Morphological correlates.", "content": "Fibrinolysis associated with oncogenic transformation. Morphological correlates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368726"}
{"pmid": "4368727", "title": "Fibrinolysis associated with oncogenic transformation. Partial purification and characterization of the cell factor, a plasminogen activator.", "content": "Fibrinolysis associated with oncogenic transformation. Partial purification and characterization of the cell factor, a plasminogen activator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368727"}
{"pmid": "4368728", "title": "Field nutrition survey of Nigerian children in Ivory Coast refugee camps.", "content": "Field nutrition survey of Nigerian children in Ivory Coast refugee camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368728"}
{"pmid": "4368729", "title": "Filtered air-positive pressure rearing of broiler chickens.", "content": "Filtered air-positive pressure rearing of broiler chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368729"}
{"pmid": "4368731", "title": "Flagyl and reduced nicotinamide adenine dinucleotide.", "content": "Flagyl and reduced nicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368731"}
{"pmid": "4368730", "title": "First night effect revisited: a clinical note.", "content": "First night effect revisited: a clinical note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368730"}
{"pmid": "4368732", "title": "Fluorescence studies of cytochrome c1 and a cytochrome c1-cytochrome c complex.", "content": "Fluorescence studies of cytochrome c1 and a cytochrome c1-cytochrome c complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368732"}
{"pmid": "4368733", "title": "Function and interaction of on and off transients in vision. II. Neurophysiology.", "content": "Function and interaction of on and off transients in vision. II. Neurophysiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368733"}
{"pmid": "4368734", "title": "Functional organization of the vestibular input to ocular motoneurons of the frog.", "content": "Functional organization of the vestibular input to ocular motoneurons of the frog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368734"}
{"pmid": "4368736", "title": "Further analysis of the resistance of a colony of rats to dextran.", "content": "Further analysis of the resistance of a colony of rats to dextran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368736"}
{"pmid": "4368735", "title": "Functional similarity of yeast and mammalian adenosine 3',5'-monophosphate-dependent protein kinases.", "content": "Functional similarity of yeast and mammalian adenosine 3',5'-monophosphate-dependent protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368735"}
{"pmid": "4368737", "title": "Further evidence for the heterogeneity of liver lysosomes.", "content": "Further evidence for the heterogeneity of liver lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368737"}
{"pmid": "4368738", "title": "Further studies on rat mast cell degranulation by IgE-anti-IgE and the inhibitory effect of drugs related to cAMP.", "content": "Further studies on rat mast cell degranulation by IgE-anti-IgE and the inhibitory effect of drugs related to cAMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368738"}
{"pmid": "4368739", "title": "Gas gangrene in a greyhound.", "content": "Gas gangrene in a greyhound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368739"}
{"pmid": "4368740", "title": "General anesthesia for surgery in the infant pigtail monkey, Macaca nemestrina.", "content": "General anesthesia for surgery in the infant pigtail monkey, Macaca nemestrina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368740"}
{"pmid": "4368741", "title": "Genetic blood markers and anthropometry of the populations in Aswan Governorate, Egypt.", "content": "Genetic blood markers and anthropometry of the populations in Aswan Governorate, Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368741"}
{"pmid": "4368742", "title": "Genetic counselling in retinoblastoma.", "content": "Genetic counselling in retinoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368742"}
{"pmid": "4368743", "title": "Genital herpesvirus infection in pregnancy.", "content": "Genital herpesvirus infection in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368743"}
{"pmid": "4368745", "title": "Glucose oxidation in alveolar macrophages: pharmacologic features.", "content": "Glucose oxidation in alveolar macrophages: pharmacologic features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368745"}
{"pmid": "4368747", "title": "Glycosyltransferases in canine respiratory tissue. Alterations in an experimentally induced hypersecretory state.", "content": "Glycosyltransferases in canine respiratory tissue. Alterations in an experimentally induced hypersecretory state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368747"}
{"pmid": "4368748", "title": "Golgi function and cell wall formation in the Conjugales.", "content": "Golgi function and cell wall formation in the Conjugales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368748"}
{"pmid": "4368746", "title": "Glycerol metabolism in Bacillus subtilis: gene-enzyme relationships.", "content": "Glycerol metabolism in Bacillus subtilis: gene-enzyme relationships. Bacillus subtilis mutants unable to catabolize glycerol (Glp mutants) were isolated and mapped. The location of the mutations on the chromosome was determined by a density transfer technique and confirmed by PBS1 transduction and transformation. The different mutations were ordered relative to each other. Mutations rendering the cells glycerol auxotrophic were also mapped and found not to be linked to the Glp mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368746"}
{"pmid": "4368744", "title": "Geriatrics. Intermediate care facilities standards.", "content": "Geriatrics. Intermediate care facilities standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368744"}
{"pmid": "4368750", "title": "Gonadotropin receptors in rat ovarian tissue. I. Localization of LH binding sites by fractionation of subcellular organelles.", "content": "Gonadotropin receptors in rat ovarian tissue. I. Localization of LH binding sites by fractionation of subcellular organelles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368750"}
{"pmid": "4368752", "title": "Goniotomy in congenital glaucoma.", "content": "Goniotomy in congenital glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368752"}
{"pmid": "4368749", "title": "Gonadal hormones and triglycerides.", "content": "Gonadal hormones and triglycerides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368749"}
{"pmid": "4368751", "title": "Gonadotropin receptors in rat ovarian tissue. II. Subcellular localization of LH binding sites by electron microscopic radioautography.", "content": "Gonadotropin receptors in rat ovarian tissue. II. Subcellular localization of LH binding sites by electron microscopic radioautography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368751"}
{"pmid": "4368755", "title": "Granular cell tumor (myoblastoma) of the bladder.", "content": "Granular cell tumor (myoblastoma) of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368755"}
{"pmid": "4368754", "title": "Granular cell myoblastoma of the head and neck.", "content": "Granular cell myoblastoma of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368754"}
{"pmid": "4368756", "title": "Granulosa cell maturation in the rat: increased binding of human chorionic gonadotropin following treatment with follicle-stimulating hormone in vivo.", "content": "Granulosa cell maturation in the rat: increased binding of human chorionic gonadotropin following treatment with follicle-stimulating hormone in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368756"}
{"pmid": "4368753", "title": "Granular cell myoblastoma located in the floor of the mouth.", "content": "Granular cell myoblastoma located in the floor of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368753"}
{"pmid": "4368758", "title": "Guinea pig insulin. II. Biological activity.", "content": "Guinea pig insulin. II. Biological activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368758"}
{"pmid": "4368757", "title": "Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures.", "content": "Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368757"}
{"pmid": "4368760", "title": "Hapten-specific tolerance in mice. II. Adoptive transfer studies and evidence for unresponsiveness in the B cells.", "content": "Hapten-specific tolerance in mice. II. Adoptive transfer studies and evidence for unresponsiveness in the B cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368760"}
{"pmid": "4368761", "title": "Health care cooperation at Aquarius Festival.", "content": "Health care cooperation at Aquarius Festival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368761"}
{"pmid": "4368759", "title": "Haem ligands of the ferricytochrome c of Ustilago sphaerogena.", "content": "Haem ligands of the ferricytochrome c of Ustilago sphaerogena. The mammalian-type cytochrome c of the basidiomycete Ustilago sphaerogena contains in a single polypeptide chain of 107 residues, two histidine residues located at positions 18 and 33, and one methionine residue situated at position 80 (Bitar et al., 1972). The reaction of Ustilago ferricytochrome c with bromoacetate at neutral pH resulted in the modification of histidine-33, but not of histidine-18 or of the invariant methionine residue. The activities of Ustilago cytochrome c with mitochondrial cytochrome c oxidase and with NADH-cytochrome c reductase were unaltered by the modification. The equilibrium constants for the formation of low-spin complexes of the ferrihaem octapeptide of horse cytochrome c (residues 14-21, including the haem bound covalently to cysteines 14 and 17) with imidazole, N(2)-acetylhistidine and monocarboxymethyl derivatives of N(2)-acetylhistidine were determined spectrophotometrically. Alkylation of the imidazole side-chain group of N(2)-acetylhistidine resulted in a marked decrease in its ability to form low-spin ferrihaem complexes. These results indicate that in Ustilago ferricytochrome c in solution histidine-33 is not involved in the central co-ordination complex. Since side-chain groups of residues other than histidine and methionine do not appear to be involved in the central complexes of other mammalian-type cytochromes c (Hettinger & Harbury, 1964, 1965; Myer & Harbury, 1965) it is likely that in Ustilago ferricytochrome c in solution at neutral pH, the side-chain groups of histidine-18 and methionine-80 are involved in the central co-ordination complex. The latter is stable over the pH range 2.6-8.4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368759"}
{"pmid": "4368762", "title": "Heat denaturation of D-glyceraldehyde-3-phosphate dehydrogenase holoenzyme.", "content": "Heat denaturation of D-glyceraldehyde-3-phosphate dehydrogenase holoenzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368762"}
{"pmid": "4368763", "title": "Helix-coil transition and conformational studies of nucleoprotein: poly(L-arginine)- and poly(L-arginine87, L-ornithine13)-DNA complexes. II. Circular dichroism.", "content": "Helix-coil transition and conformational studies of nucleoprotein: poly(L-arginine)- and poly(L-arginine87, L-ornithine13)-DNA complexes. II. Circular dichroism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368763"}
{"pmid": "4368764", "title": "Hematological and serological effects of Rauscher leukemia virus and Epstein-Barr virus on immunosuppressed newborn subhuman primates.", "content": "Hematological and serological effects of Rauscher leukemia virus and Epstein-Barr virus on immunosuppressed newborn subhuman primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368764"}
{"pmid": "4368766", "title": "Hepatic microsomal membrane: activation of glucose-6-phosphatase.", "content": "Hepatic microsomal membrane: activation of glucose-6-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368766"}
{"pmid": "4368765", "title": "Heme proteins: hemoglobin.", "content": "Heme proteins: hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368765"}
{"pmid": "4368768", "title": "Herpes nodules in the lung of the African elephant (Loxodonta africana (Blumebach, 1792)).", "content": "Herpes nodules in the lung of the African elephant (Loxodonta africana (Blumebach, 1792)).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368768"}
{"pmid": "4368771", "title": "High reactivity of kidney preparations from man, pig, beef, dog and rat for carbamyl phosphate hydrolysis.", "content": "High reactivity of kidney preparations from man, pig, beef, dog and rat for carbamyl phosphate hydrolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368771"}
{"pmid": "4368770", "title": "Herring bodies reexamined: an ultrastructural experimental investigation of the rat neural lobe.", "content": "Herring bodies reexamined: an ultrastructural experimental investigation of the rat neural lobe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368770"}
{"pmid": "4368769", "title": "Herpesviruses and cancer.", "content": "Herpesviruses and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368769"}
{"pmid": "4368772", "title": "Histidine residues and the enzyme activity of pig heart supernatant malate dehydrogenase.", "content": "Histidine residues and the enzyme activity of pig heart supernatant malate dehydrogenase. 1. Supernatant pig heart malate dehydrogenase is completely inhibited by reaction with diethyl pyrocarbonate at pH6.5, when 0.58+/-0.1 residue of ethoxycarbonylhistidine is formed per NADH-binding site. 2. Oxaloacetate and hydroxymalonate protect the enzyme from inhibition in the absence of coenzyme. 3. Limited ethoxycarbonylation does not alter the binding of NADH to the enzyme but prevents the enzyme-NADH complex from interacting with hydroxymalonate in a ternary complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368772"}
{"pmid": "4368773", "title": "Histochemical findings on sodium-potassium activated adenosine triphosphatase (NaK-ATPase) activity in the cornea.", "content": "Histochemical findings on sodium-potassium activated adenosine triphosphatase (NaK-ATPase) activity in the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368773"}
{"pmid": "4368774", "title": "Histochemical studies of hepatic enzymes in dogs subjected to lobar bile duct obstruction.", "content": "Histochemical studies of hepatic enzymes in dogs subjected to lobar bile duct obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368774"}
{"pmid": "4368776", "title": "Histologic and histochemical studies on C cells in the thyroid gland in white rats under conditions of chronic hypercalcemia induced with vitamin D3.", "content": "Histologic and histochemical studies on C cells in the thyroid gland in white rats under conditions of chronic hypercalcemia induced with vitamin D3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368776"}
{"pmid": "4368775", "title": "Histochemistry and ultrastructure of atypical myoclonus body (type II).", "content": "Histochemistry and ultrastructure of atypical myoclonus body (type II).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368775"}
{"pmid": "4368778", "title": "Hormonal effects on mammary cytology.", "content": "Hormonal effects on mammary cytology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368778"}
{"pmid": "4368777", "title": "Hormonal control of lipolysis.", "content": "Hormonal control of lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368777"}
{"pmid": "4368780", "title": "Human ecthyma contagiosum (orf) in the Faroe islands. An epidemiological and electron microscopical study.", "content": "Human ecthyma contagiosum (orf) in the Faroe islands. An epidemiological and electron microscopical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368780"}
{"pmid": "4368781", "title": "Human N-acetyl-beta-hexosaminidases: hydrolysis of N, N' diacetylchitobiose by a low molecular weight enzyme.", "content": "Human N-acetyl-beta-hexosaminidases: hydrolysis of N, N' diacetylchitobiose by a low molecular weight enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368781"}
{"pmid": "4368779", "title": "Hormone-receptor interactions with the genome of eucaryotic target cells.", "content": "Hormone-receptor interactions with the genome of eucaryotic target cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368779"}
{"pmid": "4368782", "title": "Hypoglycemia in infancy caused by beta cell nesidioblastosis.", "content": "Hypoglycemia in infancy caused by beta cell nesidioblastosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368782"}
{"pmid": "4368784", "title": "Identification of bile acids as their derivatives by 100 MHZ PMR spectroscopy.", "content": "Identification of bile acids as their derivatives by 100 MHZ PMR spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368784"}
{"pmid": "4368783", "title": "Iatrogenic disorders in epilepsy.", "content": "Iatrogenic disorders in epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368783"}
{"pmid": "4368767", "title": "Hepatoma associated with ulcerative colitis: Report of a case.", "content": "Hepatoma associated with ulcerative colitis: Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368767"}
{"pmid": "4368785", "title": "Identification of missense mutants by amino acid replacements in iso-1-cytochrome c from yeast.", "content": "Identification of missense mutants by amino acid replacements in iso-1-cytochrome c from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368785"}
{"pmid": "4368786", "title": "Identity of a newly isolated human polyomavirus from a patient with progressive multifocal leucoencephalopathy.", "content": "Identity of a newly isolated human polyomavirus from a patient with progressive multifocal leucoencephalopathy. Isolation of a strain of polyomavirus, designated COL, from the brain of a patient with progressive multifocal leucoencephalopathy is described. The COL strain is antigenically similar to JC polyomavirus, previously isolated from a brain affected by progressive multifocal leucoencephalopathy and is unrelated to BK, another human polyomavirus isolated from urine. Immunological cross testing of viruses in the Polyomavirus genus shows that there are at least six antigenic types in this group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368786"}
{"pmid": "4368787", "title": "Immunity in viral and rickettsial diseases. Round table conference.", "content": "Immunity in viral and rickettsial diseases. Round table conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368787"}
{"pmid": "4368788", "title": "Immunocytes and leukemia virus infection: effects on bone marrow and thymus cell responses and interactions.", "content": "Immunocytes and leukemia virus infection: effects on bone marrow and thymus cell responses and interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368788"}
{"pmid": "4368789", "title": "Immunodeficiency states.", "content": "Immunodeficiency states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368789"}
{"pmid": "4368791", "title": "Immunologic study of an oncornavirus isolated from a human cancer cell line.", "content": "Immunologic study of an oncornavirus isolated from a human cancer cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368791"}
{"pmid": "4368790", "title": "Immunofluorescence and elution studies in tetraparental NZB forms and is formed from CFW chimaeras and graft-versus-host diseased NZB.", "content": "Immunofluorescence and elution studies in tetraparental NZB forms and is formed from CFW chimaeras and graft-versus-host diseased NZB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368790"}
{"pmid": "4368793", "title": "Immunological studies of the protein moieties of human plasma very low-density and low-density lipoproteins.", "content": "Immunological studies of the protein moieties of human plasma very low-density and low-density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368793"}
{"pmid": "4368792", "title": "Immunological cross-reactions between two low-molecular-weight polypeptides from a murine type C virus.", "content": "Immunological cross-reactions between two low-molecular-weight polypeptides from a murine type C virus. Two low-molecular-weight type-specific virion polypeptides from the Kirsten strain of Murine leukemia virus, polypeptides p10 and p12, are immunologically related by radioimmunoassay competition techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368792"}
{"pmid": "4368795", "title": "Implications of selection for high and low adrenal response to stress.", "content": "Implications of selection for high and low adrenal response to stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368795"}
{"pmid": "4368794", "title": "Immunospecificity of chromatin nonhistone protein--DNA complexes in normal and neoplastic growth.", "content": "Immunospecificity of chromatin nonhistone protein--DNA complexes in normal and neoplastic growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368794"}
{"pmid": "4368796", "title": "Important events in photosynthesis.", "content": "Important events in photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368796"}
{"pmid": "4368797", "title": "Improved prognosis of infants mechanically ventilated for hyaline membrane disease.", "content": "Improved prognosis of infants mechanically ventilated for hyaline membrane disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368797"}
{"pmid": "4368798", "title": "In vitro labelling of childhood cancers with tritiated thymidine.", "content": "In vitro labelling of childhood cancers with tritiated thymidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368798"}
{"pmid": "4368800", "title": "In vitro synthesis of structural proteins of Semliki Forest virus directed by isolated 26 S RNA from infected cells.", "content": "In vitro synthesis of structural proteins of Semliki Forest virus directed by isolated 26 S RNA from infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368800"}
{"pmid": "4368799", "title": "In vitro synthesis of proteins by membrane-bound polyribosomes from vesicular stomatitis virus-infected HeLa cells.", "content": "In vitro synthesis of proteins by membrane-bound polyribosomes from vesicular stomatitis virus-infected HeLa cells. Membrane-bound polysomes from vesicular stomatitis virus (VSV)-infected HeLa cells synthesize predominantly three proteins in an in vitro protein synthesizing system. These three proteins have different molecular weights than the viral structural proteins, i.e., 115,000, 88,000, and 72,000. Addition of preincubated L or HeLa cell S10 or HeLa cell crude initiation factors stimulates amino acid incorporation and, furthermore, alters the pattern of proteins synthesized. Stimulated membrane-bound polysomes synthesize predominantly viral protein G and lesser amounts of N, NS, and M. In vitro synthesized proteins G and N are very similar to virion proteins G and N based on analysis of tryptic methionine-labeled peptides. Most methionine-labeled tryptic peptides of virion G protein contain no carbohydrate moieties, since about 90% of sugar-labeled peptides co-chromatograph with only about 10% of methionine-labeled peptides. Sucrose gradient analysis of the labeled RNA present in VSV-infected membrane-bound polysomes reveals a relative enrichment in a class of viral RNA sedimenting slightly faster than the total population of the 13 to 15S mRNA, as compared to a VSV-infected crude cytoplasmic extract. A number of proteins, other than the viral structural proteins, are synthesized in the cytoplasm of five lines of VSV-infected cells. One of these proteins has the same molecular weight as the major in vitro synthesized protein, P(88). In vitro synthesized protein P(88) does not appear to be a precursor of viral structural proteins G, N, or M based on pulse-chase experiments and tryptic peptide mapping. Nonstimulated membrane-bound polysomes from uninfected HeLa cells synthesize the same size distribution of proteins as nonstimulated VSV-infected membrane-bound polysomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368799"}
{"pmid": "4368801", "title": "In vitro synthesis of Rous sarcoma virus-specific RNA is catalyzed by a DNA-dependent RNA polymerase.", "content": "In vitro synthesis of Rous sarcoma virus-specific RNA is catalyzed by a DNA-dependent RNA polymerase. Synthesis of Rous sarcoma virus RNA was examined in vitro with a new assay for radioactive virus-specific RNA. Nuclei from infected and uninfected cells were incubated with ribonucleoside [alpha-(32)P]triphosphates, Mn(++), Mg(++) and (NH(4))(2)SO(4). Incorporation into total and viral RNA proceeded with similar kinetics for up to 25 min at 37 degrees . About 0.5% of the RNA synthesized by the infected system was scored as virus-specific, compared to 0.03% of the RNA from the uninfected system and 0.005% of the RNA synthesized by monkey kidney cell nuclei. Preincubation with DNase or actinomycin D completely suppressed total and virus-specific RNA synthesis. alpha-Amanitin, a specific inhibitor of eukaryotic RNA polymerase II, completely inhibited virus-specific RNA synthesis, while reducing total RNA synthesis by only 50%. We conclude that tumor virus-specific RNA is synthesized on a DNA template, most probably by the host's RNA polymerase II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368801"}
{"pmid": "4368802", "title": "In vivo and in vitro properties of a temperature sensitive mutant of infectious bovine Rhinotracheitis virus.", "content": "In vivo and in vitro properties of a temperature sensitive mutant of infectious bovine Rhinotracheitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368802"}
{"pmid": "4368804", "title": "Inactivation of trypsinogen by methane sulfonyl fluoride.", "content": "Inactivation of trypsinogen by methane sulfonyl fluoride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368804"}
{"pmid": "4368803", "title": "In vivo effects of pancreozymin, secretin, vasoactive intestinal polypeptide and pilocarpine on the levels of cyclic AMP and cyclic GMP in the rat pancreas.", "content": "In vivo effects of pancreozymin, secretin, vasoactive intestinal polypeptide and pilocarpine on the levels of cyclic AMP and cyclic GMP in the rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368803"}
{"pmid": "4368805", "title": "Incidence of clostridia in meat products.", "content": "Incidence of clostridia in meat products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368805"}
{"pmid": "4368806", "title": "Incidence of postoperative complications in patients subjected to surgery under steroid cover.", "content": "Incidence of postoperative complications in patients subjected to surgery under steroid cover.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368806"}
{"pmid": "4368807", "title": "Increase in hepatic NAD level--its effect on the redox state and on ethanol and acetaldehyde metabolism.", "content": "Increase in hepatic NAD level--its effect on the redox state and on ethanol and acetaldehyde metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368807"}
{"pmid": "4368808", "title": "Increase of serum free thyroxine following the administration of thiocyanate and other anions in vivo and in vitro.", "content": "Increase of serum free thyroxine following the administration of thiocyanate and other anions in vivo and in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368808"}
{"pmid": "4368809", "title": "Increased binding of calcitonin to renal receptors in parathyroidectomized rats.", "content": "Increased binding of calcitonin to renal receptors in parathyroidectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368809"}
{"pmid": "4368810", "title": "Increased paradoxical sleep in mice during acquisition of a shock avoidance task.", "content": "Increased paradoxical sleep in mice during acquisition of a shock avoidance task.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368810"}
{"pmid": "4368812", "title": "Increased PRPP synthetase activity in rapidly growing hepatomas.", "content": "Increased PRPP synthetase activity in rapidly growing hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368812"}
{"pmid": "4368811", "title": "Increased thermal stability of chromatin containing 5-bromodeoxyuridine-substituted DNA.", "content": "Increased thermal stability of chromatin containing 5-bromodeoxyuridine-substituted DNA. The replacement of thymidine by 5-bromodeoxyuridine in DNA leads to a greatly enhanced stability of chromatin from hepatoma tissue culture or embryonic rat pancreas, as measured by thermal chromatography on hydroxylapatite. The increased stability is directly correlated with the degree of bromodeoxyuridine substitution. On the other hand, the incorporation of bromodeoxyuridine into DNA results in a modest stabilization of purified DNA. Substitution of nucleotide also alters slightly the hyperchromicity profile generated during the thermal denaturation of purified DNA and chromatin. The observed changes can best be explained by an altered interaction between the bromodeoxyuridine-DNA and other chromatin components, presumably proteins. These results suggests that the selective effects of bromodeoxyuridine on cytodifferentiation may be due to an increased affinity of regulatory proteins for bromodeoxyuridine-DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368811"}
{"pmid": "4368813", "title": "Increases in activities of aminoacyl-tRNA synthetases during cold-treatment of dormant pear embryo.", "content": "Increases in activities of aminoacyl-tRNA synthetases during cold-treatment of dormant pear embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368813"}
{"pmid": "4368814", "title": "Induction and inhibition of ovulation in the rat by intracerebral progesterone implants.", "content": "Induction and inhibition of ovulation in the rat by intracerebral progesterone implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368814"}
{"pmid": "4368815", "title": "Infectious tenosynovitis: serologic and histopathologic response after experimental infection with a Connecticut isolate.", "content": "Infectious tenosynovitis: serologic and histopathologic response after experimental infection with a Connecticut isolate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368815"}
{"pmid": "4368816", "title": "Inflammatory pseudotumor of the lung.", "content": "Inflammatory pseudotumor of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368816"}
{"pmid": "4368817", "title": "Influence of ligands on the coenzyme dissociation constants in octopine dehydrogenase.", "content": "Influence of ligands on the coenzyme dissociation constants in octopine dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368817"}
{"pmid": "4368818", "title": "Influence of NAD+ on development of mouse blastocysts in vitro.", "content": "Influence of NAD+ on development of mouse blastocysts in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368818"}
{"pmid": "4368819", "title": "Inhibition by interferon of SV40 tumor antigen formation in cells injected with SV40 cRNA transcribed in vitro.", "content": "Inhibition by interferon of SV40 tumor antigen formation in cells injected with SV40 cRNA transcribed in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368819"}
{"pmid": "4368820", "title": "Inhibition effect of quinaldic acid on glucose-induced insulin release from isolated Langerhans islets of the rat.", "content": "Inhibition effect of quinaldic acid on glucose-induced insulin release from isolated Langerhans islets of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368820"}
{"pmid": "4368822", "title": "Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. Role of subplasmalemmal microfilaments.", "content": "Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. Role of subplasmalemmal microfilaments. Functional and morphologic effects of cytochalasin B on the cultivated macrophage were examined to determine the basis for plasma membrane movements of the type required for endocytosis and/or spreading on a substratum. Inhibition of phagocytosis and changes in cell shape by cytochalasin B exhibited nearly identical dose-response curves requiring 2-5 x 10(-6) M and 1-2 x 10(-5) M cytochalasin B to inhibit these functions by 50% and 100%, respectively. In contrast, hexose transport was ten times more sensitive to the drug requiring 2-3 x 10(-7) M cytochalasin B to achieve 50% inhibition of 2-deoxyglucose uptake. Inhibition of phagocytosis and changes in cell shape could not be explained solely by drug effects on hexose transport. Analysis of serial thin sections showed that cytochalasin B doses inhibitory for hexose transport had no effect on distribution or organization of either of the two subplasmalemmal microfilament types. However, cytochalasin B concentrations (2.0 x 10(-5) M) that inhibited phagocytosis and altered cell shape disorganized and/or disrupted oriented bundles of 40-50-A subplasmalemmal microfilaments, but had no effect on the microfilamentous network. Comparative dose-response studies showing positive correlations among cytochalasin B effects on phagocytosis, changes in cell shape, and alterations in oriented subplasmalemmal microfilament bundles provide additional support for the hypothesis that microfilamentous structures play a role in translocation of plasma membrane required for endocytosis and cell motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368822"}
{"pmid": "4368821", "title": "Inhibition of a vesicular stomatitis virus mutant by rifampin.", "content": "Inhibition of a vesicular stomatitis virus mutant by rifampin. Rifampin reversibly inhibits the intracellular replication of a VSV mutant, whereas a revertant variant selected from this viral population, as well as the wild strain, are not affected by this drug. Rifampin inhibits transcriptase activity of the sensitive mutant only and, consequently, total viral RNA synthesis decreases significantly in the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368821"}
{"pmid": "4368823", "title": "Inhibition of rat liver Ca2+, Mg2+-dependent endonuclease activity by nicotinamide adenine dinucleotide and poly (adenosine diphosphate ribose) synthetase.", "content": "Inhibition of rat liver Ca2+, Mg2+-dependent endonuclease activity by nicotinamide adenine dinucleotide and poly (adenosine diphosphate ribose) synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368823"}
{"pmid": "4368824", "title": "Inhibition of AMV DNA polymerase by polyriboadenylic acid containing epsilon-adenosine residues.", "content": "Inhibition of AMV DNA polymerase by polyriboadenylic acid containing epsilon-adenosine residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368824"}
{"pmid": "4368826", "title": "Inhibitory effects of central hypertensive activity of angiotensin I and II by 1-sar-8-ala-angiotensin II (saralasin acetate).", "content": "Inhibitory effects of central hypertensive activity of angiotensin I and II by 1-sar-8-ala-angiotensin II (saralasin acetate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368826"}
{"pmid": "4368825", "title": "Inhibition of 3',5'-nucleotide phosphodiesterase in guinea pig cerebral cortical slices.", "content": "Inhibition of 3',5'-nucleotide phosphodiesterase in guinea pig cerebral cortical slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368825"}
{"pmid": "4368827", "title": "Inhibitory effects of 2-thiouracil and 2-thiouracil metabolites on enzymes involved in pyrimidine nucleotide biosynthesis.", "content": "Inhibitory effects of 2-thiouracil and 2-thiouracil metabolites on enzymes involved in pyrimidine nucleotide biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368827"}
{"pmid": "4368828", "title": "Insulin secretion: multifactorial regulation for a single process of release. The Minkowski award lecture delivered on September 7, 1972 before the European Association for the study of Diabetes at Madrid, Spain.", "content": "Insulin secretion: multifactorial regulation for a single process of release. The Minkowski award lecture delivered on September 7, 1972 before the European Association for the study of Diabetes at Madrid, Spain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368828"}
{"pmid": "4368831", "title": "Interactions of glucagon, gut glucagon, vasoactive intestinal polypeptide and secretin with liver and fat cell plasma membranes: binding to specific sites and stimulation of adenylate cyclase.", "content": "Interactions of glucagon, gut glucagon, vasoactive intestinal polypeptide and secretin with liver and fat cell plasma membranes: binding to specific sites and stimulation of adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368831"}
{"pmid": "4368829", "title": "Interaction of human serum high density lipoproteins with triglycerides in vitro.", "content": "Interaction of human serum high density lipoproteins with triglycerides in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368829"}
{"pmid": "4368830", "title": "Interaction of phalloidin with actin.", "content": "Interaction of phalloidin with actin. Phalloidin, a toxic bicyclic peptide of rapid action from the toadstool, Amanita phalloides, gives rise to polymerization of G-actin to filamentous structures (Ph-actin) in a medium of low ionic strength. Ph-actin closely resembles the microfilaments found in liver membrane fractions (Ph-filaments) after in vivo or in vitro poisoning. Both phalloidin induced filaments are resistant to 0.6 M KI in contrast to F-actin, and become decorated by heavy meromyosin. After preincubation with cytochalasin B significantly fewer actin filaments are observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368830"}
{"pmid": "4368832", "title": "Interactions of LH and hCG with testicular gonadotropin receptors.", "content": "Interactions of LH and hCG with testicular gonadotropin receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368832"}
{"pmid": "4368833", "title": "Interconversion of ampicillin and hetacillin in vitro.", "content": "Interconversion of ampicillin and hetacillin in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368833"}
{"pmid": "4368834", "title": "Intermembrane electron transfer in mitochondrial and microsomal systems.", "content": "Intermembrane electron transfer in mitochondrial and microsomal systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368834"}
{"pmid": "4368835", "title": "Intermolecular steric interactions and lipid chain fluidity in phospholipid multibilayers. A spin label study.", "content": "Intermolecular steric interactions and lipid chain fluidity in phospholipid multibilayers. A spin label study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368835"}
{"pmid": "4368836", "title": "Interstitial cell tumor of the testicle in rabbits: a report of two cases.", "content": "Interstitial cell tumor of the testicle in rabbits: a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368836"}
{"pmid": "4368838", "title": "Intracranial causes of headache.", "content": "Intracranial causes of headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368838"}
{"pmid": "4368839", "title": "Intranuclear annulate lamellae in Ehrlich ascites tumour cells.", "content": "Intranuclear annulate lamellae in Ehrlich ascites tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368839"}
{"pmid": "4368837", "title": "Intestinal glycoproteins of germfree rats. 3. Characterization of a water-soluble glycoprotein fraction.", "content": "Intestinal glycoproteins of germfree rats. 3. Characterization of a water-soluble glycoprotein fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368837"}
{"pmid": "4368840", "title": "Intranuclear concentration of lysosomal hydrolases in steroid target cells. Acute response to administration of gonadal hormones in vivo.", "content": "Intranuclear concentration of lysosomal hydrolases in steroid target cells. Acute response to administration of gonadal hormones in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368840"}
{"pmid": "4368841", "title": "Introduction of mouse L cell nucleus into heterologous mammalian cells.", "content": "Introduction of mouse L cell nucleus into heterologous mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368841"}
{"pmid": "4368842", "title": "Investigation of a family with hypertrophic neuropathy resembling Roussy-Levy syndrome. Clinical, electrophysiologic, histologic, and biochemical studies.", "content": "Investigation of a family with hypertrophic neuropathy resembling Roussy-Levy syndrome. Clinical, electrophysiologic, histologic, and biochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368842"}
{"pmid": "4368843", "title": "Investigation of recognition sites in valine tRNA I (Baker's yeast) by dissected molecule method.", "content": "Investigation of recognition sites in valine tRNA I (Baker's yeast) by dissected molecule method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368843"}
{"pmid": "4368844", "title": "Investigations on the release of membrane-bound glyceraldehyde-3-phosphate dehydrogenase.", "content": "Investigations on the release of membrane-bound glyceraldehyde-3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368844"}
{"pmid": "4368846", "title": "Is cortisol metabolized as it dissociates from glucocorticoid receptors in thymus cells?", "content": "Is cortisol metabolized as it dissociates from glucocorticoid receptors in thymus cells?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368846"}
{"pmid": "4368845", "title": "Iontophoretic and autoradiographic studies on the role of proline in nervous transmission.", "content": "Iontophoretic and autoradiographic studies on the role of proline in nervous transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368845"}
{"pmid": "4368849", "title": "Isolation and identification of infectious bursal disease virus in Lebanon.", "content": "Isolation and identification of infectious bursal disease virus in Lebanon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368849"}
{"pmid": "4368848", "title": "Isolation and characterization of plasma and smooth membranes of the marine diatom Nitzschia alba.", "content": "Isolation and characterization of plasma and smooth membranes of the marine diatom Nitzschia alba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368848"}
{"pmid": "4368847", "title": "Isolated hypoaldosteronism associated with idiopathic hypoparathyroidism.", "content": "Isolated hypoaldosteronism associated with idiopathic hypoparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368847"}
{"pmid": "4368850", "title": "Isolation and partial characterization of a glycoprotein from bovine cortical bone.", "content": "Isolation and partial characterization of a glycoprotein from bovine cortical bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368850"}
{"pmid": "4368852", "title": "Japanese encephalitis vaccination in Thailand.", "content": "Japanese encephalitis vaccination in Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368852"}
{"pmid": "4368851", "title": "Isolation of a myelogenous leukemia-inducing virus from mice infected with the Friend virus complex.", "content": "Isolation of a myelogenous leukemia-inducing virus from mice infected with the Friend virus complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368851"}
{"pmid": "4368853", "title": "Juvenile fibroma of antral origin.", "content": "Juvenile fibroma of antral origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368853"}
{"pmid": "4368854", "title": "Juvenile GM1 gangliosidosis. Occurrence with absence of two beta-galactosidase components.", "content": "Juvenile GM1 gangliosidosis. Occurrence with absence of two beta-galactosidase components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368854"}
{"pmid": "4368855", "title": "Kinetic techniques for the investigation of amino acid: tRNA ligases (aminoacyl-tRNA synthetases, amino acid activating enzymes).", "content": "Kinetic techniques for the investigation of amino acid: tRNA ligases (aminoacyl-tRNA synthetases, amino acid activating enzymes).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368855"}
{"pmid": "4368857", "title": "Klebsiella air sacculitis in the owl monkey (Aotus trivirgatus).", "content": "Klebsiella air sacculitis in the owl monkey (Aotus trivirgatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368857"}
{"pmid": "4368856", "title": "Kinetics of aminoacyl-tRNA synthetases catalyzed ATP-PPi exchange.", "content": "Kinetics of aminoacyl-tRNA synthetases catalyzed ATP-PPi exchange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368856"}
{"pmid": "4368859", "title": "Letter: Basal cell adenomas.", "content": "Letter: Basal cell adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368859"}
{"pmid": "4368860", "title": "Letter: Feline leukemia virus.", "content": "Letter: Feline leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368860"}
{"pmid": "4368862", "title": "Letter: On the possible role of cAMP in receptor dark adaptation.", "content": "Letter: On the possible role of cAMP in receptor dark adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368862"}
{"pmid": "4368863", "title": "Letter: Relief of pain in women with genital herpes.", "content": "Letter: Relief of pain in women with genital herpes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368863"}
{"pmid": "4368861", "title": "Letter: Letter: Nucleotide distribution in bacterial DNA's differing in G plus C content.", "content": "Letter: Letter: Nucleotide distribution in bacterial DNA's differing in G plus C content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368861"}
{"pmid": "4368865", "title": "Levels of adenosine 3',5'-cyclic monophosphate in the cerebral cortex of aging rats.", "content": "Levels of adenosine 3',5'-cyclic monophosphate in the cerebral cortex of aging rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368865"}
{"pmid": "4368864", "title": "Leukocyte chemotaxis in vivo. II. Analysis of the selective inhibition of neutrophil or mononuclear cell accumulation.", "content": "Leukocyte chemotaxis in vivo. II. Analysis of the selective inhibition of neutrophil or mononuclear cell accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368864"}
{"pmid": "4368858", "title": "Laboratory aids in the diagnosis of tumors of the pancreas.", "content": "Laboratory aids in the diagnosis of tumors of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368858"}
{"pmid": "4368866", "title": "Lightly haptenated proteins induce IgM-deficient antibody responses.", "content": "Lightly haptenated proteins induce IgM-deficient antibody responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368866"}
{"pmid": "4368868", "title": "Lipid acceptor in UDPglucuronic acid metabolism in rat liver microsomes.", "content": "Lipid acceptor in UDPglucuronic acid metabolism in rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368868"}
{"pmid": "4368870", "title": "Lipid phase transitions and drug interactions.", "content": "Lipid phase transitions and drug interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368870"}
{"pmid": "4368871", "title": "Lipids of potato tubers. 3. Effect of growth and storage on lipid content of the potato tuber.", "content": "Lipids of potato tubers. 3. Effect of growth and storage on lipid content of the potato tuber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368871"}
{"pmid": "4368869", "title": "Lipid composition and cholesterol esterification in lymph.", "content": "Lipid composition and cholesterol esterification in lymph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368869"}
{"pmid": "4368873", "title": "Lipotropic and adrenocorticotropic hormones. Biological activities of the carboxyl-modified hormones.", "content": "Lipotropic and adrenocorticotropic hormones. Biological activities of the carboxyl-modified hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368873"}
{"pmid": "4368872", "title": "Lipoproteins and lipolytic plasma enzymes in a case of tangier disease.", "content": "Lipoproteins and lipolytic plasma enzymes in a case of tangier disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368872"}
{"pmid": "4368874", "title": "Liver and spleen in rats after intravenous injection of Lipiodol Ultra-Fluide and 99Tcm-sulphide colloid.", "content": "Liver and spleen in rats after intravenous injection of Lipiodol Ultra-Fluide and 99Tcm-sulphide colloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368874"}
{"pmid": "4368875", "title": "Liver cirrhosis and hepatoma in rats induced by 3-benzylsydnone-4-acetamide.", "content": "Liver cirrhosis and hepatoma in rats induced by 3-benzylsydnone-4-acetamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368875"}
{"pmid": "4368876", "title": "Local immunity to avian infectious bronchitis in tracheal organ culture.", "content": "Local immunity to avian infectious bronchitis in tracheal organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368876"}
{"pmid": "4368877", "title": "Long-term stimulatory effects of adenosine 3',5'-cyclic monophosphate on nuclear and cytoplasmic protein synthesis of rat hepatocytes in primary culture.", "content": "Long-term stimulatory effects of adenosine 3',5'-cyclic monophosphate on nuclear and cytoplasmic protein synthesis of rat hepatocytes in primary culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368877"}
{"pmid": "4368878", "title": "Long-term survival after massive liver resection for hepatocellular carcinoma.", "content": "Long-term survival after massive liver resection for hepatocellular carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368878"}
{"pmid": "4368879", "title": "Lumbar myelography and arachnoiditis.", "content": "Lumbar myelography and arachnoiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368879"}
{"pmid": "4368881", "title": "Lymphocyte tubuloreticular structures in lupus erythematosus. Correlation with disease activity.", "content": "Lymphocyte tubuloreticular structures in lupus erythematosus. Correlation with disease activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368881"}
{"pmid": "4368880", "title": "Luteinizing hormone receptors in luteinized rat ovaries.", "content": "Luteinizing hormone receptors in luteinized rat ovaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368880"}
{"pmid": "4368882", "title": "Lymphotic inclusions in I-cell disease.", "content": "Lymphotic inclusions in I-cell disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368882"}
{"pmid": "4368884", "title": "LH does not increase cyclic AMP in the thyroid.", "content": "LH does not increase cyclic AMP in the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368884"}
{"pmid": "4368883", "title": "Lysosomal labilization: rapid, target-specific effect of ACTH.", "content": "Lysosomal labilization: rapid, target-specific effect of ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368883"}
{"pmid": "4368867", "title": "Linitis plastica carcinoma of the intestine: Report of four cases.", "content": "Linitis plastica carcinoma of the intestine: Report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368867"}
{"pmid": "4368886", "title": "Magnetic resonance studies on glutamate dehydrogenase.", "content": "Magnetic resonance studies on glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368886"}
{"pmid": "4368885", "title": "LH-RH interaction with the pituitary plasma membrane is affected by sex steroids.", "content": "LH-RH interaction with the pituitary plasma membrane is affected by sex steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368885"}
{"pmid": "4368888", "title": "Malignant chemodectoma of the superior mediastinum with elevated urinary homovanillic acid.", "content": "Malignant chemodectoma of the superior mediastinum with elevated urinary homovanillic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368888"}
{"pmid": "4368889", "title": "Malignant melanoma in a snake.", "content": "Malignant melanoma in a snake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368889"}
{"pmid": "4368890", "title": "Mass fragmentographic determination of eleven estrogens in the body fluids of pregnant and nonpregnant subjects.", "content": "Mass fragmentographic determination of eleven estrogens in the body fluids of pregnant and nonpregnant subjects. Mass fragmentographic determinations of 11 estrogens in urine, bile, or plasma of pregnant and nonpregnant subjects were made.  The estrogens (estriol, estrone, 2-methoxyestrone, estradiol-17beta, estradiol-17alpha, 16-epiestriol, 17-epiestriol, 16-alpha-hydroxyestrone, 16beta-hydroxyestrone, 16oxoestradiol-17beta, and 15alpha-hydroxyestrone) were quantitatively  determined in bile from 1 male and 3 postmenopausal women, in the urine of a nonpregnant woman, and in a 20 ml pool of late pregnancy plasma obtained from 10 women.  The specificity of mass fragmentography as compared with gas chromatography is considered better because a characteristic ion is monitored rather than the total ion current measured by flame ionization detection and reliable measurements can  be made in the presence of larger amounts of impurities, resulting in a shortened fractionation procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368890"}
{"pmid": "4368891", "title": "Mass spectra of trimethylsilyl ethers of 2H-labelled mono- and diglycerides.", "content": "Mass spectra of trimethylsilyl ethers of 2H-labelled mono- and diglycerides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368891"}
{"pmid": "4368893", "title": "Mathematics of hormone-receptor interaction. I. Basic principles.", "content": "Mathematics of hormone-receptor interaction. I. Basic principles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368893"}
{"pmid": "4368894", "title": "Measurement of the second and fourth components of rat complement.", "content": "Measurement of the second and fourth components of rat complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368894"}
{"pmid": "4368887", "title": "Major or minor tranquilizers for relief of common symptoms of psychoneurosis?", "content": "Major or minor tranquilizers for relief of common symptoms of psychoneurosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368887"}
{"pmid": "4368895", "title": "Measurement of the sequence complexity of cloned Moloney murine leukemia virus 60 to 70S RNA: evidence for a haploid genome.", "content": "Measurement of the sequence complexity of cloned Moloney murine leukemia virus 60 to 70S RNA: evidence for a haploid genome. The sequence complexity of the 60-70S RNA complex from Moloney murine leukemia virus (M-MuLV) was determined by measuring the annealing rate of radioactively labeled virus-specific DNA with M-MuLV 60-70S RNA in conditions of vast RNA excess. The M-MuLV RNA annealing rate, characterized by the quantity C(r)t((1/2)), was compared with the C(r)t((1/2)) values for annealing of poliovirus 35S RNA (2.6 x 10(6) molecular weight) with poliovirus-specific DNA and Sindbis virus 42S RNA (4.3 x 10(6) molecular weight) with Sindbis-specific DNA. M-MuLV-specific DNA was prepared in vitro by the endogenous DNA polymerase reaction of M-MuLV virions, and poliovirus and Sindbis virus DNAs were prepared by incubation of viral RNA and DNA polymerase purified from avian myeloblastosis virus and an oligo deoxynucleotide primer. The poliovirus and Sindbis virus DNAs were sedimented through alkaline sucrose gradients, and those portions of the DNA with sizes similar to the M-MuLV DNA were selected out for the annealing measurements. M-MuLV was cloned on NIH-3T3 cells because it appeared possible that the standard source of M-MuLV for these experiments was a mixture of viruses. The annealing measurements indicated a sequence complexity of approximately 9 x 10(6) daltons for the cloned M-MuLV 60-70S RNA when standardized to poliovirus and Sindbis virus RNAs. This value supports the hypothesis that each of the 35S RNA subunits of M-MuLV 60-70S RNA has a different base sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368895"}
{"pmid": "4368897", "title": "Mechanism of cell contact-dependent glycolipid synthesis: further studies with glycolipid-glass complex.", "content": "Mechanism of cell contact-dependent glycolipid synthesis: further studies with glycolipid-glass complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368897"}
{"pmid": "4368896", "title": "Mechanism of bacitracin action: a specific lipid-peptide interaction.", "content": "Mechanism of bacitracin action: a specific lipid-peptide interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368896"}
{"pmid": "4368892", "title": "Maternal cardiovascular adjustments to pregnancy.", "content": "Maternal cardiovascular adjustments to pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368892"}
{"pmid": "4368898", "title": "Mechanism of control of skeletal-muscle contraction by dantrolene sodium.", "content": "Mechanism of control of skeletal-muscle contraction by dantrolene sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368898"}
{"pmid": "4368900", "title": "Mechanisms of resistance of human acute leukaemia cells to cytosine arabinoside.", "content": "Mechanisms of resistance of human acute leukaemia cells to cytosine arabinoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368900"}
{"pmid": "4368899", "title": "Mechanism of the interferon-induced block of mRNA translation in mouse L cells: reversal of the block by transfer RNA.", "content": "Mechanism of the interferon-induced block of mRNA translation in mouse L cells: reversal of the block by transfer RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368899"}
{"pmid": "4368901", "title": "Mechanisms of spasticity.", "content": "Mechanisms of spasticity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368901"}
{"pmid": "4368902", "title": "Meiotic maturation of the mammalian oocyte in vitro: effect of dibutyryl cyclic AMP on protein synthesis.", "content": "Meiotic maturation of the mammalian oocyte in vitro: effect of dibutyryl cyclic AMP on protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368902"}
{"pmid": "4368904", "title": "Membrane filtration in the study of antimicrobial drugs.", "content": "Membrane filtration in the study of antimicrobial drugs. A membrane filtration apparatus of the type employed in water bacteriology was used in the assessment of some antimicrobial drugs. Samples of liquid nutrient medium inoculated with a small number of bacteria, to which dilutions of a drug had been added before incubation and again later, were filtered and the membranes washed and incubated on solid medium. By this means differences between bacteriostatic and bactericidal action were clearly demonstrated. It was shown that staphylococci which had survived exposure to penicillin or gentamicin at levels below their minimum bactericidal concentrations remained fully responsive to the subsequent addition of more of the same drug, while those which had survived exposure to chloramphenicol or clindamycin were not significantly affected by further addition, so that neither of the latter two drugs was bactericidal against the strain of organism used. Bactericidal effects were also demonstrated by benzyl penicillin against Clostridium welchii and ampicillin against Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368904"}
{"pmid": "4368905", "title": "Membrane orientation in vesicles from Micrococcus lysodeikticus cells.", "content": "Membrane orientation in vesicles from Micrococcus lysodeikticus cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368905"}
{"pmid": "4368906", "title": "Membrane receptors.", "content": "Membrane receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368906"}
{"pmid": "4368908", "title": "Metabolic effects of 2-phenylethanol, 1,1-dimethylphenylethanol, periodate and succinic anhydride on intact yeast cells and on fermenting preparations from lyophilized yeast.", "content": "Metabolic effects of 2-phenylethanol, 1,1-dimethylphenylethanol, periodate and succinic anhydride on intact yeast cells and on fermenting preparations from lyophilized yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368908"}
{"pmid": "4368909", "title": "Metabolism of progesterone in the chick oviduct: relation to the progesterone receptor and biological activity.", "content": "Metabolism of progesterone in the chick oviduct: relation to the progesterone receptor and biological activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368909"}
{"pmid": "4368907", "title": "Metabolic effects of N6-substituted adenosines in rats.", "content": "Metabolic effects of N6-substituted adenosines in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368907"}
{"pmid": "4368910", "title": "Metabolites and the incorporation of L-leucine into rabbit insulin in vitro.", "content": "Metabolites and the incorporation of L-leucine into rabbit insulin in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368910"}
{"pmid": "4368911", "title": "Methaqualone: an irrational hypnotic.", "content": "Methaqualone: an irrational hypnotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368911"}
{"pmid": "4368912", "title": "Methodological problems and clinical validity of an ACTH radioimmunoassay method applied to extracted plasma samples.", "content": "Methodological problems and clinical validity of an ACTH radioimmunoassay method applied to extracted plasma samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368912"}
{"pmid": "4368913", "title": "Methoxyflurane anesthesia for Rana pipiens.", "content": "Methoxyflurane anesthesia for Rana pipiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368913"}
{"pmid": "4368914", "title": "Methylglyoxal formation during glucose catabolism by Pseudomonas saccharophila. Identification of methylglyoxal synthase.", "content": "Methylglyoxal formation during glucose catabolism by Pseudomonas saccharophila. Identification of methylglyoxal synthase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368914"}
{"pmid": "4368915", "title": "Micro hemagglutination-inhibition test for detection of CELO virus antibodies.", "content": "Micro hemagglutination-inhibition test for detection of CELO virus antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368915"}
{"pmid": "4368916", "title": "Microcirculation and hypoxia.", "content": "Microcirculation and hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368916"}
{"pmid": "4368917", "title": "Mineral metabolism and skeletal development of lambs affected by Trichostrongylus colubriformis.", "content": "Mineral metabolism and skeletal development of lambs affected by Trichostrongylus colubriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368917"}
{"pmid": "4368918", "title": "Minimal change and focal sclerotic lesions in lipoid nephrosis.", "content": "Minimal change and focal sclerotic lesions in lipoid nephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368918"}
{"pmid": "4368903", "title": "Melatonin: cellular effects on live stentors correlated with the inhibition of colchicine-binding to microtubule protein.", "content": "Melatonin: cellular effects on live stentors correlated with the inhibition of colchicine-binding to microtubule protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368903"}
{"pmid": "4368920", "title": "Mobility of protein molecules in Micrococcus lysodeikticus membranes.", "content": "Mobility of protein molecules in Micrococcus lysodeikticus membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368920"}
{"pmid": "4368919", "title": "Mitochondrial heterosis.", "content": "Mitochondrial heterosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368919"}
{"pmid": "4368921", "title": "Modification of cysteine residues with sodium 2-bromoethanesulfonate. The application of S-sulfoethylated peptides in automatic Edman degradation.", "content": "Modification of cysteine residues with sodium 2-bromoethanesulfonate. The application of S-sulfoethylated peptides in automatic Edman degradation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368921"}
{"pmid": "4368923", "title": "Modifications in the purified rabbit skeletal muscle apophosphorylase-b assay of serum pyridoxal phosphate levels.", "content": "Modifications in the purified rabbit skeletal muscle apophosphorylase-b assay of serum pyridoxal phosphate levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368923"}
{"pmid": "4368922", "title": "Modifications in the chromosomal proteins of SV-40 transformed WI-38 human diploid fibroblasts.", "content": "Modifications in the chromosomal proteins of SV-40 transformed WI-38 human diploid fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368922"}
{"pmid": "4368924", "title": "Modified radioimmunoassay for murine sarcoma-leukemia virus group-specific antigen.", "content": "Modified radioimmunoassay for murine sarcoma-leukemia virus group-specific antigen. Iodination of disrupted Moloney strain murine sarcoma-leukemia virus resulted in labeled group-specific (gs) protein which was subsequently purified on an isoelectrofocusing column. This iodinated purified gs antigen, prepared from a relatively small quantity of purified virus, was used in a radioimmunoassay. A radioimmunoassay inhibition method was developed so that antibody specific for mammalian C-type gs antigen could be measured in undiluted or low dilutions of test serum without altering the known reagents of the test. The gs antigen isolated from purified Moloney strain murine sarcoma-leukemia virus has an isoelectric point (pH 5.95) which is significantly lower than that reported for other murine leukemia viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368924"}
{"pmid": "4368925", "title": "Modulation of the baroreceptor reflex by central administration of angiotensin.", "content": "Modulation of the baroreceptor reflex by central administration of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368925"}
{"pmid": "4368926", "title": "Molecular basis of the biological function of molybdenum. Molybdenum-free sulfite oxidase from livers of tungsten-treated rats.", "content": "Molecular basis of the biological function of molybdenum. Molybdenum-free sulfite oxidase from livers of tungsten-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368926"}
{"pmid": "4368927", "title": "Molecular basis of the biological function of molybdenum. Molybdenum-free xanthine oxidase from livers of tungsten-treated rats.", "content": "Molecular basis of the biological function of molybdenum. Molybdenum-free xanthine oxidase from livers of tungsten-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368927"}
{"pmid": "4368928", "title": "Molecular orbital studies of the conformation around the 5 position in angiotensin II.", "content": "Molecular orbital studies of the conformation around the 5 position in angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368928"}
{"pmid": "4368929", "title": "Molecular orbital study on the interaction between coenzymes and enzymes; NAD+ or NADH and dehydrogenases.", "content": "Molecular orbital study on the interaction between coenzymes and enzymes; NAD+ or NADH and dehydrogenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368929"}
{"pmid": "4368931", "title": "Morphological basis of diffusion through the iris vessels in the dynamics of the aqueous humour.", "content": "Morphological basis of diffusion through the iris vessels in the dynamics of the aqueous humour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368931"}
{"pmid": "4368930", "title": "Molecular weight of microsomal glucose-6-phosphatase of rat and human liver.", "content": "Molecular weight of microsomal glucose-6-phosphatase of rat and human liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368930"}
{"pmid": "4368933", "title": "Motor end-plate fine structure in acrylamide dying-back neuropathy: a sequential morphometric study.", "content": "Motor end-plate fine structure in acrylamide dying-back neuropathy: a sequential morphometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368933"}
{"pmid": "4368932", "title": "Morphological observations on visceral leishmaniasis in the Sudan.", "content": "Morphological observations on visceral leishmaniasis in the Sudan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368932"}
{"pmid": "4368935", "title": "Mulibrey nanism; an inherited dysmorphic syndrome with characteristic ocular findings.", "content": "Mulibrey nanism; an inherited dysmorphic syndrome with characteristic ocular findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368935"}
{"pmid": "4368936", "title": "Multicentric chemodectomata at high altitude. A case report and review of the literature.", "content": "Multicentric chemodectomata at high altitude. A case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368936"}
{"pmid": "4368934", "title": "Motor unit recruitment as reflected by muscle fibre glycogen loss in a prosimian (bushbaby) after running and jumping.", "content": "Motor unit recruitment as reflected by muscle fibre glycogen loss in a prosimian (bushbaby) after running and jumping. A qualitative histochemical assessment of glycogen loss in biopsies was made in bush-babies after running and jumping. Glycogen loss was related to the specific type of exercise. After running, glycogen loss was greatest in the slow-twitch oxidative fibre and depletion in the fast-twitch oxidative glycolytic fibres was similarly greater than in the fast-twitch glycolytic fibres. After jumping, the opposite pattern of glycogen utilization occurred (FG>FOG>SO).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368934"}
{"pmid": "4368937", "title": "Multiple aggregation states of phosphoribosyladenosine triphosphate synthetase.", "content": "Multiple aggregation states of phosphoribosyladenosine triphosphate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368937"}
{"pmid": "4368938", "title": "Multiple forms of solubilized gonadotropin receptors from the rat testis.", "content": "Multiple forms of solubilized gonadotropin receptors from the rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368938"}
{"pmid": "4368940", "title": "Murine cytomegalovirus-infected liver: depletion of acid phosphatase with concomitant increase of alkaline phosphate.", "content": "Murine cytomegalovirus-infected liver: depletion of acid phosphatase with concomitant increase of alkaline phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368940"}
{"pmid": "4368939", "title": "Multiple primary carcinomas of respiratory tract: primary carcinoma of larynx followed by primary carcinomas involving two lungs consecutively.", "content": "Multiple primary carcinomas of respiratory tract: primary carcinoma of larynx followed by primary carcinomas involving two lungs consecutively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368939"}
{"pmid": "4368941", "title": "Muscle length and neuromuscular transmission in the frog.", "content": "Muscle length and neuromuscular transmission in the frog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368941"}
{"pmid": "4368943", "title": "Mutagens in the biosphere.", "content": "Mutagens in the biosphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368943"}
{"pmid": "4368942", "title": "Mutagenicity of thioxanthenes (hycanthone, lucanthone and four indazole derivatives) at the TK locus in cultured mammalian cells.", "content": "Mutagenicity of thioxanthenes (hycanthone, lucanthone and four indazole derivatives) at the TK locus in cultured mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368942"}
{"pmid": "4368944", "title": "Mutant of Salmonella typhimurium that channels infecting bacteriophage P22 toward lysogenization.", "content": "Mutant of Salmonella typhimurium that channels infecting bacteriophage P22 toward lysogenization. A slowly growing, polymyxin-sensitive mutant of Salmonella typhimurium was isolated. Wild-type phage P22 form plaques on the mutant at 5 x 10(-4), the frequency observed on wild-type hosts. All P22 clear mutants form plaques with near normal frequency. The inability of the mutant to form plaques is correlated with an increase in lysogenization frequency. The cause of the increased lysogenization frequency is not known, but it is not the result of overproduction of cyclic adenosine 5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368944"}
{"pmid": "4368945", "title": "Myelin enzymes and protein metabolism.", "content": "Myelin enzymes and protein metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368945"}
{"pmid": "4368947", "title": "Mössbauer studies of some complexes of the undecapeptide of cytochrome c.", "content": "Mössbauer studies of some complexes of the undecapeptide of cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368947"}
{"pmid": "4368950", "title": "Neo-natal mortality of puppies in Queensland caused by canine herpesvirus infection.", "content": "Neo-natal mortality of puppies in Queensland caused by canine herpesvirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368950"}
{"pmid": "4368949", "title": "Needle biopsies in pulmonary diagnostics.", "content": "Needle biopsies in pulmonary diagnostics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368949"}
{"pmid": "4368951", "title": "Neonatal hematuria.", "content": "Neonatal hematuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368951"}
{"pmid": "4368946", "title": "Myocardial function and lipid metabolism in the chronic alcoholic animal.", "content": "Myocardial function and lipid metabolism in the chronic alcoholic animal. In view of the variables that obscure the pathogenesis of cardiomyopathy, a study was undertaken in mongrel dogs fed ethanol as 36% of calories for up to 22 mo. Both the experimental and control groups maintained body weight, hematocrit, plasma vitamin, and protein levels. Left ventricular function was evaluated in the intact anesthetized dog using indicator dilution for end-diastolic and stroke volume determinations. During increased afterload with angiotensin, the ethanol group exhibited a larger rise of end-diastolic pressure (P<0.01), whereas end-diastolic and stroke volume responses were significantly less than in controls. Preload increments with saline elicited a significantly higher end-diastolic pressure rise in the ethanol group (P<0.01). No hypertrophy, inflammation, or fibrosis was present and it was postulated that the enhanced diastolic stiffness was related to accumulation of Alcian Blue-positive material in the ventricular interstitium. To evaluate myocardial lipid metabolism, [1-(14)C]oleic acid was infused systemically. Plasma specific activity and myocardial lipid uptake were similar in both groups. There was a significantly increased incorporation of label into triglyceride, associated with a reduced (14)CO(2) production, considered the basis for a twofold increment of triglyceride content. In addition, diminished incorporation of [(14)C]oleic acid into phospholipid was observed accompanied by morphologic abnormalities of cardiac cell membranes. Potassium loss and sodium gain, like the lipid alteration, was more prominent in the subendocardium. Thus, chronic ethanol ingestion in this animal model is associated with abnormalities of ventricular function without evident malnutrition, analogous to the preclinical malfunction described in the human alcoholic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368946"}
{"pmid": "4368952", "title": "Neural-tube defects and herpesvirus type 2--test of a hypothesis.", "content": "Neural-tube defects and herpesvirus type 2--test of a hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368952"}
{"pmid": "4368953", "title": "Neurilemmoma of the choroid in Recklinghausen's disease.", "content": "Neurilemmoma of the choroid in Recklinghausen's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368953"}
{"pmid": "4368955", "title": "Neutralizing antibodies to herpesvirus types 1 and 2 in carcinoma of the cervix, carcinoma in situ and cervical dysplasia.", "content": "Neutralizing antibodies to herpesvirus types 1 and 2 in carcinoma of the cervix, carcinoma in situ and cervical dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368955"}
{"pmid": "4368954", "title": "Neurophysiologic mechanisms of hemiplegic and paraplegic spasticity: implications for therapy.", "content": "Neurophysiologic mechanisms of hemiplegic and paraplegic spasticity: implications for therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368954"}
{"pmid": "4368956", "title": "Neutralizing antibodies to herpesvirus types 1 and 2 in Montreal women.", "content": "Neutralizing antibodies to herpesvirus types 1 and 2 in Montreal women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368956"}
{"pmid": "4368957", "title": "New experimental approaches.", "content": "New experimental approaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368957"}
{"pmid": "4368948", "title": "N-oxide formation and related reactions in drug metabolism.", "content": "N-oxide formation and related reactions in drug metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368948"}
{"pmid": "4368958", "title": "No evidence for a carbohydrate moiety affecting the clearance of circulating human leukocyte interferon in rabbits.", "content": "No evidence for a carbohydrate moiety affecting the clearance of circulating human leukocyte interferon in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368958"}
{"pmid": "4368959", "title": "Non-metastatic neurological minifestations of malignant disease.", "content": "Non-metastatic neurological minifestations of malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368959"}
{"pmid": "4368960", "title": "Non-polio virus interference with oral polio vaccine immunization: possible influence of physical climate and socio-economic status.", "content": "Non-polio virus interference with oral polio vaccine immunization: possible influence of physical climate and socio-economic status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368960"}
{"pmid": "4368961", "title": "Non-transmitting neuromuscular junctions during an early stage of end-plate reinnervation.", "content": "Non-transmitting neuromuscular junctions during an early stage of end-plate reinnervation. 1. Electrophysiological studies were made on regenerating motor end-plates in frog cutaneous pectoris muscle after crushing the motor nerve.2. The pattern of degenerative and regenerative changes is similar to that already described for the frog sartorius, although it occurs more quickly in the cutaneous pectoris. Resumption of synaptic transmission first occurs after 9 days, in muscle fibres closest to the nerve crush. During the subsequent 12 days synaptic contact is progressively re-established across the muscle.3. During the period of regeneration muscle fibres can be found which have been reinnervated, but which do not produce an end-plate potential in response to stimulation of the nerve trunk. This is referred to as the ;non-transmitting' stage of regeneration.4. Increases in extracellular potassium, addition of lanthanum to the bath and focal extracellular stimulation all indicate that the axon terminals at non-transmitting junctions do have a releasable supply of neurotransmitter. Focal stimulation occasionally sets up active responses in these nerve terminals.5. It is concluded that this ;non-transmitting' stage results from failure of action potential propagation in the regenerating neurone proximal to the end-plate region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368961"}
{"pmid": "4368962", "title": "Nonfunctioning nonchromaffin paraganglioma of the pancreas.", "content": "Nonfunctioning nonchromaffin paraganglioma of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368962"}
{"pmid": "4368964", "title": "Nuclear concentration of estriol in superfused human endometrium; competition with estradiol.", "content": "Nuclear concentration of estriol in superfused human endometrium; competition with estradiol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368964"}
{"pmid": "4368963", "title": "Novikoff hepatoma nuclear 8-18S RNA.", "content": "Novikoff hepatoma nuclear 8-18S RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368963"}
{"pmid": "4368965", "title": "Nuclear receptor-estrogen complexes of rat uteri: concentration-time-response parameters.", "content": "Nuclear receptor-estrogen complexes of rat uteri: concentration-time-response parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368965"}
{"pmid": "4368967", "title": "Nucleotide pyrophosphatase, a sialoglycoprotein located on the hepatocyte surface.", "content": "Nucleotide pyrophosphatase, a sialoglycoprotein located on the hepatocyte surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368967"}
{"pmid": "4368968", "title": "Nucleotide sequence analysis of bacteriophage DNA.", "content": "Nucleotide sequence analysis of bacteriophage DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368968"}
{"pmid": "4368966", "title": "Nuclear ribonucleoprotein complexes containing polyadenylate from mouse ascites cells.", "content": "Nuclear ribonucleoprotein complexes containing polyadenylate from mouse ascites cells. Nuclear poly(A)-containing RNA of mouse ascites cells can be extracted in the form of 15-17S ribonucleoprotein complexes under conditions in which the bulk of the heterogeneous nuclear RNA is released as 30S complexes. The poly(A)-containing fraction of nuclear extracts has been resolved into two distinct components, 15 and 17 S; neither contains the two polypeptides of 30S ribonucleoprotein. The 17S particle contains approximately six polypeptide species of molecular masses 17,000-30,000 daltons. The 15S complex has four distinct polypeptides of higher molecular mass, including a prominent 80,000-dalton species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368966"}
{"pmid": "4368969", "title": "NADH brain surface scanning and 3-D computer display.", "content": "NADH brain surface scanning and 3-D computer display.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368969"}
{"pmid": "4368970", "title": "NADH, a physiological electron donor in clostridial nitrogen fixation.", "content": "NADH, a physiological electron donor in clostridial nitrogen fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368970"}
{"pmid": "4368971", "title": "NH2-terminal sequence of yeast inorganic pyrophosphatase.", "content": "NH2-terminal sequence of yeast inorganic pyrophosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368971"}
{"pmid": "4368972", "title": "N6-(delta2-isopentenyl)adenosine 5'-monophosphate: formation and effect on purine metabolism in cellular and enzymatic systems.", "content": "N6-(delta2-isopentenyl)adenosine 5'-monophosphate: formation and effect on purine metabolism in cellular and enzymatic systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368972"}
{"pmid": "4368973", "title": "Observations on the structural arrangement of the somatic sensory innervation in the iris of mammals.", "content": "Observations on the structural arrangement of the somatic sensory innervation in the iris of mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368973"}
{"pmid": "4368976", "title": "Occupational therapist in home health.", "content": "Occupational therapist in home health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368976"}
{"pmid": "4368975", "title": "Observations on vibrio eltor.", "content": "Observations on vibrio eltor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368975"}
{"pmid": "4368974", "title": "Observations on uptake of herpes simplex virus in organized cultures of mammalian nervous tissue.", "content": "Observations on uptake of herpes simplex virus in organized cultures of mammalian nervous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368974"}
{"pmid": "4368977", "title": "On the development of a well-defined source of superoxide ion for studies with biological systems.", "content": "On the development of a well-defined source of superoxide ion for studies with biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368977"}
{"pmid": "4368978", "title": "On the electron donor property of veratrine.", "content": "On the electron donor property of veratrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368978"}
{"pmid": "4368979", "title": "On the interaction of periodate oxidized GDP and its borohydride reduction product with the elongation factors Tu and G from Escherichia coli.", "content": "On the interaction of periodate oxidized GDP and its borohydride reduction product with the elongation factors Tu and G from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368979"}
{"pmid": "4368980", "title": "On the mechanism of erythropoietin-induced differentiation. 13. The role of sialic acid in erythropoietin action.", "content": "On the mechanism of erythropoietin-induced differentiation. 13. The role of sialic acid in erythropoietin action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368980"}
{"pmid": "4368981", "title": "On the nature of the spin coupling between the iron-sulfur clusters in the eight-iron ferredoxins.", "content": "On the nature of the spin coupling between the iron-sulfur clusters in the eight-iron ferredoxins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368981"}
{"pmid": "4368983", "title": "One-step separation of human plasma angiotensinogen from renin.", "content": "One-step separation of human plasma angiotensinogen from renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368983"}
{"pmid": "4368984", "title": "Oral infection of Culicoides variipennis with bluetongue virus: development of susceptible and resistant lines from a colony population.", "content": "Oral infection of Culicoides variipennis with bluetongue virus: development of susceptible and resistant lines from a colony population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368984"}
{"pmid": "4368985", "title": "Origin of asymmetry in biomolecules.", "content": "Origin of asymmetry in biomolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368985"}
{"pmid": "4368986", "title": "Oxaziridines as possible intermediates in flavin monooxygenases.", "content": "Oxaziridines as possible intermediates in flavin monooxygenases. The enzymatic hydroxylation reactions of flavin monooxygenases are suggested to involve an oxaziridine as the active oxygenating agent. The chemistry of these monooxygenases and their nonenzymatic model systems are consistent with an oxaziridine intermediate. Several advantages of the oxaziridine model over the previously proposed \"carbonyl oxide\" and flavin peroxide models are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368986"}
{"pmid": "4368987", "title": "Oxygen poisoning in the unanesthetized brain: correlation of the oxidation-reduction state of pyridine nucleotide with electrical activity.", "content": "Oxygen poisoning in the unanesthetized brain: correlation of the oxidation-reduction state of pyridine nucleotide with electrical activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368987"}
{"pmid": "4368988", "title": "Paediatric ophthalmology in Northern Finland--a population investigation.", "content": "Paediatric ophthalmology in Northern Finland--a population investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368988"}
{"pmid": "4368989", "title": "Pancreatic surgery in the 1960s.", "content": "Pancreatic surgery in the 1960s.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368989"}
{"pmid": "4368990", "title": "Parental compliance with postdischarge recommendations for retarded children.", "content": "Parental compliance with postdischarge recommendations for retarded children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368990"}
{"pmid": "4368991", "title": "Partial inhibition of hydroxyurea on liver tumors induced by N, N-dimethyl-4-aminoazobenzene.", "content": "Partial inhibition of hydroxyurea on liver tumors induced by N, N-dimethyl-4-aminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368991"}
{"pmid": "4368992", "title": "Partial nephrectomy--a pathological evaluation.", "content": "Partial nephrectomy--a pathological evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368992"}
{"pmid": "4368993", "title": "Participation of mononuclear phagocytes in chronic inflammatory diseases.", "content": "Participation of mononuclear phagocytes in chronic inflammatory diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368993"}
{"pmid": "4368994", "title": "Particles similar to mouse leukaemia virus in Ehrlich's ascites carcinoma and in reticulum cell noeplasms type B. An electron microscopic study in mice.", "content": "Particles similar to mouse leukaemia virus in Ehrlich's ascites carcinoma and in reticulum cell noeplasms type B. An electron microscopic study in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368994"}
{"pmid": "4368996", "title": "Patterns of spontaneous cortisol and growth hormone secretion in rhesus monkeys during the sleep-waking cycle.", "content": "Patterns of spontaneous cortisol and growth hormone secretion in rhesus monkeys during the sleep-waking cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368996"}
{"pmid": "4368995", "title": "Patterns of changes in brain carbohydrate metabolites, amino acids and organic phosphates at increased carbon dioxide tensions.", "content": "Patterns of changes in brain carbohydrate metabolites, amino acids and organic phosphates at increased carbon dioxide tensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368995"}
{"pmid": "4368997", "title": "Pellicular immobilized enzymes.", "content": "Pellicular immobilized enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368997"}
{"pmid": "4368982", "title": "Oncolytic action of prostaglandins.", "content": "Oncolytic action of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368982"}
{"pmid": "4368998", "title": "Pelvic arteriography in the diagnosis of malignant trophoblastic disease.", "content": "Pelvic arteriography in the diagnosis of malignant trophoblastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368998"}
{"pmid": "4368999", "title": "Peptide hormones.", "content": "Peptide hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4368999"}
{"pmid": "4369000", "title": "Peptide synthesis.", "content": "Peptide synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369000"}
{"pmid": "4369001", "title": "Persistence of complement-fixing antibodies in guinea pig sera serially collected in large volumes.", "content": "Persistence of complement-fixing antibodies in guinea pig sera serially collected in large volumes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369001"}
{"pmid": "4369002", "title": "Persistence of late SV40 genome transcription after inhibition of DNA relication by cytosine arabinoside.", "content": "Persistence of late SV40 genome transcription after inhibition of DNA relication by cytosine arabinoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369002"}
{"pmid": "4369003", "title": "Persistent albuminuria and meningitis caused by congenital cytomegalovirus infection. A case report of cytomegalic inclusion disease.", "content": "Persistent albuminuria and meningitis caused by congenital cytomegalovirus infection. A case report of cytomegalic inclusion disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369003"}
{"pmid": "4369004", "title": "Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in smooth muscles.", "content": "Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in smooth muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369004"}
{"pmid": "4369005", "title": "Phase specific surface autoantigens on membranes of fetus and tumors.", "content": "Phase specific surface autoantigens on membranes of fetus and tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369005"}
{"pmid": "4369006", "title": "Phosphatase activity of methicillin-resistant and methicillin-sensitive cells of Staphylococcus aureus.", "content": "Phosphatase activity of methicillin-resistant and methicillin-sensitive cells of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369006"}
{"pmid": "4369007", "title": "Phospholipids and acyl groups of subcellular membrane fractions from human intracranial tumors.", "content": "Phospholipids and acyl groups of subcellular membrane fractions from human intracranial tumors. The phospholipids from subcellular fractions of human intracranial tumors were examined. For comparison, microsomes were isolated from a fetal human brain and from the gray matter of adult human brains. The subcellular membranes of tumors had a higher protein-to-phospholipid ratio than the normal brain membranes. The microsomes from tumors had a lower proportion of diacylglycerophosphorylethanolamine and higher proportions of alkenylacylglycerophosphorylcholine and sphingomyelin (plus diacylglycerophosphorylinositol) than microsomes from the gray matter. Also, the ratios of alkenylacylglycerophosphorylethanolamine to diacylglycerophosphorylethanolamine were higher in the tumors than in the normal controls. The acyl groups of ethanolamine phosphoglycerides in tumor microsomes had relatively more 18:1, 18:2, and 20:4(n - 6) and less 18:0, 22:4(n - 6), and 22:6(n - 3) than the adult brain gray matter. Except for the increase in 18:2, acyl group changes in choline phosphoglycerides between tumors and controls were not as extensive as in the ethanolamine phosphoglycerides. The characteristic features of phospholipids and their constituent acyl groups of tumors were often present in all the subcellular fractions. Although the acyl group profiles of the tumor phosphoglycerides were in closer resemblance to the fetal brain than to the adult brain, other differences were observed. Results indicate that neoplastic brain cells are unique in their cellular composition, and consequently they deviate from the normal neurons and glials in metabolism and functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369007"}
{"pmid": "4369008", "title": "Phosphonolipids. XXVI. Mixed-acid phosphonocephalins: synthesis of alpha'-stearoyl-beta-oleoyl-l-alpha-glyceryl-(2-aminoethyl)phosphonate.", "content": "Phosphonolipids. XXVI. Mixed-acid phosphonocephalins: synthesis of alpha'-stearoyl-beta-oleoyl-l-alpha-glyceryl-(2-aminoethyl)phosphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369008"}
{"pmid": "4369009", "title": "Phosphorylation of a zymogen granule membrane polypeptide from rat pancreas.", "content": "Phosphorylation of a zymogen granule membrane polypeptide from rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369009"}
{"pmid": "4369010", "title": "Phosphorylation of nuclear proteins during muscle differentiation in vitro.", "content": "Phosphorylation of nuclear proteins during muscle differentiation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369010"}
{"pmid": "4369011", "title": "Phosphorylation of proteins in rat liver. Endogenous phosphorylation and dephosphorylation of proteins from smooth and rough endoplasmic reticulum and free ribosomes.", "content": "Phosphorylation of proteins in rat liver. Endogenous phosphorylation and dephosphorylation of proteins from smooth and rough endoplasmic reticulum and free ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369011"}
{"pmid": "4369012", "title": "Photoinactivation of ammonia oxidation in Nitrosomonas.", "content": "Photoinactivation of ammonia oxidation in Nitrosomonas. Photoinactivation of ammonia oxidation in cells of Nitrosomonas was shown to follow first-order kinetics with a rate constant proportional to incident light intensity. The action spectrum for photoinactivation consisted of a broad peak in the ultraviolet range, where both hydroxylamine and ammonia oxidation were affected, and a shoulder at approximately 410 nm where only ammonia oxidation was affected. In photoinactivated cells, hydroxylamine but not ammonia was oxidized to nitrite and hydroxylamine but not ammonia caused reduction of cytochromes in vivo. The amount per cell of the following constituents was not measurably altered by photoinactivation: cytochromes b, c, a, and P460; ubiquinone; phospholipid; free amino acids; hydroxylamine-dependent nitrite synthetase; nitrite reductase; p-phenylenediamine oxidase; and cytochrome c oxidase. Malonaldehyde or lipid peroxides were not detected in photoinactivated cells. Photoinactivation was prevented (i) under anaerobic conditions, (ii) in the presence of methanol, allylthiourea, thiosemicarbazide, hydroxylamine, ethylxanthate, or CO at concentrations wich caused 100% inhibition of ammonia oxidation, and (iii) at concentrations of ammonia or hydroxylamine which gave a rapid rate of nitrite production. Recovery of ammonia oxidation activity in 90% inactivated cells took place in 6 h, required an energy and/or nitrogen source, and was inhibited by 400 mug of chloramphenicol per ml.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369012"}
{"pmid": "4369013", "title": "Phylogenetic aspects of adrenocortical activity during the process of adaptation.", "content": "Phylogenetic aspects of adrenocortical activity during the process of adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369013"}
{"pmid": "4369014", "title": "Physical and chemical properties of opossum hemoglobin. A hemoglobin containing glutamine at position 58 (E7) in the alpha subunit.", "content": "Physical and chemical properties of opossum hemoglobin. A hemoglobin containing glutamine at position 58 (E7) in the alpha subunit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369014"}
{"pmid": "4369015", "title": "Physico-chemical properties of chromatin of mouse sperm nuclei in heterokaryons with Chinese hamster cells.", "content": "Physico-chemical properties of chromatin of mouse sperm nuclei in heterokaryons with Chinese hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369015"}
{"pmid": "4369016", "title": "Plant sterol metabolism. Enzymatic cleavage of the 9beta, 19beta-cyclopropane ring of cyclopropyl sterols in bramble tissue cultures.", "content": "Plant sterol metabolism. Enzymatic cleavage of the 9beta, 19beta-cyclopropane ring of cyclopropyl sterols in bramble tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369016"}
{"pmid": "4369017", "title": "Plants gathered as foodstuffs by the Transkeian peoples.", "content": "Plants gathered as foodstuffs by the Transkeian peoples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369017"}
{"pmid": "4369019", "title": "Plasma cortisol in children with fulminating meningococcal infection.", "content": "Plasma cortisol in children with fulminating meningococcal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369019"}
{"pmid": "4369018", "title": "Plasma adenosine 3',5'-cyclic monophosphate in human hypertension.", "content": "Plasma adenosine 3',5'-cyclic monophosphate in human hypertension. In a previous study we observed an increase in urinary cyclic AMP in labile hypertension in the upright position and during isoproterenol infusion, in contrast to a decrease in control subjects. In the present study we measured the plasma level of cyclic AMP in control subjects and patients with various types of hypertension. We obtained the following results: (1) plasma cyclic AMP increases in response to upright posture in control subjects and hypertensive patients; (2) values of cyclic AMP in the recumbent and upright positions are comparable in control subjects and patients with essential hypertension, but are significantly higher in those with true renovascular hypertension due to bilateral renal artery stenosis; (3) propranolol inhibits the increase of plasma cyclic AMP in response to posture in control subjects, but has an opposite effect in labile hypertension where there is a further increase; (4) the rise in blood pressure in pheochromocytoma is associated with a considerable increase in plasma cyclic AMP.Present and previous data suggest that kidney handling of cyclic AMP is abnormal in hypertension, and that the specific defect may be related to the type of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369018"}
{"pmid": "4369022", "title": "Platelet electrophoresis: the present position.", "content": "Platelet electrophoresis: the present position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369022"}
{"pmid": "4369021", "title": "Plasminogen, the serum proenzyme activated by factors from cells transformed by oncogenic viruses.", "content": "Plasminogen, the serum proenzyme activated by factors from cells transformed by oncogenic viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369021"}
{"pmid": "4369020", "title": "Plasma post-heparin lipolytic activity in patients with malabsorption: effect of intravenous fat administration.", "content": "Plasma post-heparin lipolytic activity in patients with malabsorption: effect of intravenous fat administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369020"}
{"pmid": "4369023", "title": "Platelet retention in glass bead columns: further evidence for the importance of ADP.", "content": "Platelet retention in glass bead columns: further evidence for the importance of ADP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369023"}
{"pmid": "4369024", "title": "Polymyositis without inflammation.", "content": "Polymyositis without inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369024"}
{"pmid": "4369025", "title": "Polypeptide composition of rat high density lipoprotein: characterization by SDS-gel electrophoresis.", "content": "Polypeptide composition of rat high density lipoprotein: characterization by SDS-gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369025"}
{"pmid": "4369026", "title": "Polypeptide distribution of the main lipoprotein density classes separated from human plasma by rate zonal ultracentrifugation.", "content": "Polypeptide distribution of the main lipoprotein density classes separated from human plasma by rate zonal ultracentrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369026"}
{"pmid": "4369027", "title": "Population dynamics of mitochondria. I. A model for the role to ACTH in the degradation of adrenocortical mitochondria.", "content": "Population dynamics of mitochondria. I. A model for the role to ACTH in the degradation of adrenocortical mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369027"}
{"pmid": "4369028", "title": "Possible dapsone-induced peripheral neuropathy in dermatitis herpetiformis.", "content": "Possible dapsone-induced peripheral neuropathy in dermatitis herpetiformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369028"}
{"pmid": "4369029", "title": "Postsynaptic responses of motor cortex neurons of cats to sensory stimulation of different modalities.", "content": "Postsynaptic responses of motor cortex neurons of cats to sensory stimulation of different modalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369029"}
{"pmid": "4369031", "title": "Preliminary crystallographic data for cytochrome c' of Rhodopseudomonas palustris.", "content": "Preliminary crystallographic data for cytochrome c' of Rhodopseudomonas palustris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369031"}
{"pmid": "4369032", "title": "Prenatal viral infection with particular reference to cytomegaloviruses.", "content": "Prenatal viral infection with particular reference to cytomegaloviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369032"}
{"pmid": "4369033", "title": "Preparation and properties of a cell-free, hormonally responsive adenylate cyclase from guinea pig brain.", "content": "Preparation and properties of a cell-free, hormonally responsive adenylate cyclase from guinea pig brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369033"}
{"pmid": "4369035", "title": "Preparation of avian ribosomes with low levels of contaminating elongation factors.", "content": "Preparation of avian ribosomes with low levels of contaminating elongation factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369035"}
{"pmid": "4369034", "title": "Preparation of adenosine nucleotide derivatives suitable for affinity chromatography.", "content": "Preparation of adenosine nucleotide derivatives suitable for affinity chromatography. Methods of synthesizing a series of chemically-defined AMP, ADP, ATP, adenylyl imidodiphosphate and pyrophosphate derivatives suitable for affinity chromatography are extensively described. Each derivative has a single primary amino group at the end of a hexamethylene ;spacer' chain for attachment to CNBr-activated agarose. The synthesis of the derivative where the ;spacer' arm is attached directly to the 8 position of the adenine ring to produce 8-(6-aminohexyl)amino-AMP involves the direct bromination of AMP in the 8 position followed by displacement of the halogen by 1,6-diaminohexane. This monophosphate derivative can then be converted into the corresponding di- or triphosphate forms by direct phosphate condensation with carbonyl di-imidazole. A second series of adenosine phosphate derivatives with the phosphate moieties unsubstituted has been similarly prepared from N(6)-(6-aminohexyl)-AMP (Guilford et al., 1972). A third type of ligand has been synthesized by condensing the phosphoryl imidazolide of AMP with 6-aminohex-1-yl phosphate. This compound, P(1)-(6-aminohex-1-yl) P(2)-(5'-adenosyl) pyrophosphate, has an unsubstituted adenine ring. The synthesis of a fourth type of ligand, 6-aminohex-1-yl pyrophosphate, was done by heating 6-aminohexan-1-ol with crystalline pyrophosphoric acid under reduced pressure. The structures of the synthesized compounds were confirmed by chemical, electrophoretic and chromatographic methods and by u.v. spectrometry. The general applicability of the synthetic methods used is discussed in relation to the preparation of other affinity adsorbents. Examples are given where these derivatives have been successful in reversibly binding dehydrogenases, kinases and myosin and its proteolytic subfragments. The partial purification of rat liver glucokinase on an ADP derivative is shown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369034"}
{"pmid": "4369036", "title": "Preparation of 3-chloroacetylpyridine adenine dinucleotide: an alkylating analogue of NAD+.", "content": "Preparation of 3-chloroacetylpyridine adenine dinucleotide: an alkylating analogue of NAD+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369036"}
{"pmid": "4369037", "title": "Pressure response of pulmonary vasculature to vasoconstricting agents.", "content": "Pressure response of pulmonary vasculature to vasoconstricting agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369037"}
{"pmid": "4369038", "title": "Prevention by metallothionein of cadmium-induced inhibition of vitamin D activation reaction in kidney.", "content": "Prevention by metallothionein of cadmium-induced inhibition of vitamin D activation reaction in kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369038"}
{"pmid": "4369030", "title": "Prediction of breast cancer response to endocrine therapy.", "content": "Prediction of breast cancer response to endocrine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369030"}
{"pmid": "4369039", "title": "Prevention of hemolysis by bivalent metal ions during virus-induced fusion of erythrocytes with Ehrlich ascites tumor cells.", "content": "Prevention of hemolysis by bivalent metal ions during virus-induced fusion of erythrocytes with Ehrlich ascites tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369039"}
{"pmid": "4369041", "title": "Primary cause of decreased functional reserve in the liver of icteric patients and rats.", "content": "Primary cause of decreased functional reserve in the liver of icteric patients and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369041"}
{"pmid": "4369043", "title": "Primary mucinous (adenocystic) carcinoma of the skin.", "content": "Primary mucinous (adenocystic) carcinoma of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369043"}
{"pmid": "4369040", "title": "Prevention of the generalized Shwartzman reaction and endotoxin lethality by polymyxin B localized in tissues.", "content": "Prevention of the generalized Shwartzman reaction and endotoxin lethality by polymyxin B localized in tissues. Pretreatment with multiple doses of polymyxin B and colistimethate was evaluated as to its ability to sequester sufficient antibiotic in tissues to neutralize the effects of endotoxin in three animal models. Animals were challenged with endotoxin 24, 48, or 72 h after the last dose of antibiotic when there was minimal or not detectable drug in serum. Pretreatment with polymyxin B was successful in preventing the generalized Shwartzman reaction in rabbits and reducing endotoxin lethality in mice; however, large doses (20 mg per kg per day for 2 or 4 days) were required. Prolongation by more than 24 h of the interval between the last dose of polymyxin B and endotoxin challenge resulted in reduction or loss of protection. Dogs were unable to tolerate the high polymyxin B dosage which was protective in the mouse and rabbit. Lower, nontoxic doses of polymyxin B in dogs did not prevent endotoxin shock and lethality, even when challenged as soon as 1 h after the last dose. Pretreatment with colistimethate was ineffective in all three animal models.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369040"}
{"pmid": "4369042", "title": "Primary hepatoma and invasive lobular carcinoma of breast without cirrhosis.", "content": "Primary hepatoma and invasive lobular carcinoma of breast without cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369042"}
{"pmid": "4369044", "title": "Primary structure of lobster-muscle arginine kinase. Isolation and characterization of the fragments produced by cyanogen-bromide cleavage.", "content": "Primary structure of lobster-muscle arginine kinase. Isolation and characterization of the fragments produced by cyanogen-bromide cleavage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369044"}
{"pmid": "4369045", "title": "Probenecide sensitive 3'-5'-cyclic AMP secretion by isoproterenol stimulated glial cells in culture.", "content": "Probenecide sensitive 3'-5'-cyclic AMP secretion by isoproterenol stimulated glial cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369045"}
{"pmid": "4369047", "title": "Proceedings: Effect of temperature on the regulatory properties of poikilothermic enzymes.", "content": "Proceedings: Effect of temperature on the regulatory properties of poikilothermic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369047"}
{"pmid": "4369049", "title": "Proceedings: Feed-back control of corticotrophin in the rat.", "content": "Proceedings: Feed-back control of corticotrophin in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369049"}
{"pmid": "4369048", "title": "Proceedings: Effects of electrical and chemical stimulation of the central nervous system on sodium chloride and water intake.", "content": "Proceedings: Effects of electrical and chemical stimulation of the central nervous system on sodium chloride and water intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369048"}
{"pmid": "4369051", "title": "Proceedings: Humoral control of periodical changes of nervous excitability.", "content": "Proceedings: Humoral control of periodical changes of nervous excitability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369051"}
{"pmid": "4369050", "title": "Proceedings: Glycine receptors in the cerebral cortex are probably transport receptors.", "content": "Proceedings: Glycine receptors in the cerebral cortex are probably transport receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369050"}
{"pmid": "4369046", "title": "Proceedings: Do the anterior pituitary and adrenal cortex participate in the reflex response of the adrenal medulla to arterial hypoxia?", "content": "Proceedings: Do the anterior pituitary and adrenal cortex participate in the reflex response of the adrenal medulla to arterial hypoxia?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369046"}
{"pmid": "4369053", "title": "Proceedings: Intraneuronal distributions and metabolic pathways of the adrenergic neurotransmitter.", "content": "Proceedings: Intraneuronal distributions and metabolic pathways of the adrenergic neurotransmitter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369053"}
{"pmid": "4369052", "title": "Proceedings: Hydroxylation of steroids and electron microscopy in adrenals from rats bearing an ACTH secreting tumor.", "content": "Proceedings: Hydroxylation of steroids and electron microscopy in adrenals from rats bearing an ACTH secreting tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369052"}
{"pmid": "4369055", "title": "Proceedings: Malacoplakia in childhood.", "content": "Proceedings: Malacoplakia in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369055"}
{"pmid": "4369054", "title": "Proceedings: Liver and adipose tissue metabolism in rats with acute insulin deficiency induced by total pancreatectomy.", "content": "Proceedings: Liver and adipose tissue metabolism in rats with acute insulin deficiency induced by total pancreatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369054"}
{"pmid": "4369056", "title": "Proceedings: Modification of the receptive field properties of neurones in the visual cortex by bicuculline, a GABA antagonist.", "content": "Proceedings: Modification of the receptive field properties of neurones in the visual cortex by bicuculline, a GABA antagonist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369056"}
{"pmid": "4369057", "title": "Proceedings: Neurotrophic effects upon muscles and receptors of the cat's tongue.", "content": "Proceedings: Neurotrophic effects upon muscles and receptors of the cat's tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369057"}
{"pmid": "4369058", "title": "Proceedings: Pancreas and hypophysis in liver ketone body production.", "content": "Proceedings: Pancreas and hypophysis in liver ketone body production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369058"}
{"pmid": "4369059", "title": "Proceedings: Physiological implication of the metabolism of androgen in brain.", "content": "Proceedings: Physiological implication of the metabolism of androgen in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369059"}
{"pmid": "4369060", "title": "Proceedings: Primary hepatic cancer in childhood.", "content": "Proceedings: Primary hepatic cancer in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369060"}
{"pmid": "4369062", "title": "Proceedings: Some similarities and differences between renin and sustained pressor principle.", "content": "Proceedings: Some similarities and differences between renin and sustained pressor principle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369062"}
{"pmid": "4369061", "title": "Proceedings: Regulatory mechanisms of sodium appetite.", "content": "Proceedings: Regulatory mechanisms of sodium appetite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369061"}
{"pmid": "4369063", "title": "Proceedings: Stimulation and inhibition of renin production in monolayer cultures of kidney cells.", "content": "Proceedings: Stimulation and inhibition of renin production in monolayer cultures of kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369063"}
{"pmid": "4369065", "title": "Proceedings: The brain renin-angiotensin system. Its physiological role.", "content": "Proceedings: The brain renin-angiotensin system. Its physiological role.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369065"}
{"pmid": "4369064", "title": "Proceedings: Synthetic angiotensin inhibiting peptides.", "content": "Proceedings: Synthetic angiotensin inhibiting peptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369064"}
{"pmid": "4369066", "title": "Proceedings: The effect of reserpine on pituitary-adrenocortical function in the rat.", "content": "Proceedings: The effect of reserpine on pituitary-adrenocortical function in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369066"}
{"pmid": "4369068", "title": "Proceedings: The renin--angiotensin system in experimental renal hypertension.", "content": "Proceedings: The renin--angiotensin system in experimental renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369068"}
{"pmid": "4369069", "title": "Proceedings: The role of the presynaptic receptors in regulating noradrenaline overflow by nerve stimulation.", "content": "Proceedings: The role of the presynaptic receptors in regulating noradrenaline overflow by nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369069"}
{"pmid": "4369070", "title": "Prognostic value of ERG (oscillatory potential) in juvenile diabetics.", "content": "Prognostic value of ERG (oscillatory potential) in juvenile diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369070"}
{"pmid": "4369067", "title": "Proceedings: The mechanism of action of estrogens.", "content": "Proceedings: The mechanism of action of estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369067"}
{"pmid": "4369071", "title": "Prolactin stimulation of estrogen receptor in vitro in 7,12 dimethylbenz(A)anthracene-induced mammary tumor.", "content": "Prolactin stimulation of estrogen receptor in vitro in 7,12 dimethylbenz(A)anthracene-induced mammary tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369071"}
{"pmid": "4369072", "title": "Prolonged culture of Visna virus in human astrocytes.", "content": "Prolonged culture of Visna virus in human astrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369072"}
{"pmid": "4369073", "title": "Prolylcarboxypeptidase in biological fluids.", "content": "Prolylcarboxypeptidase in biological fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369073"}
{"pmid": "4369074", "title": "Properties of feline leukemia virus. II. In vitro labeling of the polypeptides.", "content": "Properties of feline leukemia virus. II. In vitro labeling of the polypeptides. Radioactive labeling of proteins from guanidine-hydrochloride disrupted feline leukemia virus was done in vitro by attaching [(3)H]methyl groups to protein amino groups with reductive alkylation. When in vitro labeled disrupted virus was analyzed by gel filtration in the presence of 6 M guanidine-hydrochloride the expected six major and one minor protein peaks were detected. When the same preparation was analyzed by immunodiffusion, the three antigens tested were found to have retained their antigenic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369074"}
{"pmid": "4369075", "title": "Properties of partially purified liver microsomal cytochrome P-450: acceptance of two electrons during anaerobic titration.", "content": "Properties of partially purified liver microsomal cytochrome P-450: acceptance of two electrons during anaerobic titration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369075"}
{"pmid": "4369077", "title": "Properties of the nicotinamide adenine dinucleotide-specific isocitrate dehydrogenase from Blastocladiella emersonii.", "content": "Properties of the nicotinamide adenine dinucleotide-specific isocitrate dehydrogenase from Blastocladiella emersonii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369077"}
{"pmid": "4369076", "title": "Properties of the abnormal human plasma lipoprotein (LP-X) characteristic of cholestasis after chemical modification with succinic anhydride.", "content": "Properties of the abnormal human plasma lipoprotein (LP-X) characteristic of cholestasis after chemical modification with succinic anhydride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369076"}
{"pmid": "4369078", "title": "Properties of the Sezary lymphoid cell. An ultrastructural analysis.", "content": "Properties of the Sezary lymphoid cell. An ultrastructural analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369078"}
{"pmid": "4369080", "title": "Prostaglandin inhibition of cartilage chondromucoprotein synthesis: concept of \"intrinsic activity\".", "content": "Prostaglandin inhibition of cartilage chondromucoprotein synthesis: concept of \"intrinsic activity\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369080"}
{"pmid": "4369079", "title": "Properties of Clostridium perfringens (welchii) type-A alpha-toxin (phospholipase C) purified by electrofocusing.", "content": "Properties of Clostridium perfringens (welchii) type-A alpha-toxin (phospholipase C) purified by electrofocusing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369079"}
{"pmid": "4369081", "title": "Prostaglandin receptors in human and ovine adrenal glands: binding and stimulation of adenyl cyclase in subcellular preparations.", "content": "Prostaglandin receptors in human and ovine adrenal glands: binding and stimulation of adenyl cyclase in subcellular preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369081"}
{"pmid": "4369082", "title": "Protein kinases in testes of adult and prepuberal rats.", "content": "Protein kinases in testes of adult and prepuberal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369082"}
{"pmid": "4369083", "title": "Protein metabolism in tumor cells at various stages of growth in vivo.", "content": "Protein metabolism in tumor cells at various stages of growth in vivo. Protein metabolism of Yoshida ascites hepatoma cells was studied in the early phase of logarithmic proliferation and in the following stage in which cell mass remains constant (resting phase). The rate of protein synthesis was measured by a short-time incorporation of [(8)H]lysine, while degradation was concurrently assessed by following the decrease of specific activity of [(14)C]lysine-labeled proteins. Most of the labeled amino acid injected intraperitoneally into the animal was immediately available for the tumor cells, with only a minor loss towards the extra-ascitic compartment. It was thus possible to calculate the dilution of the isotope in the ascitic pool of the lysine, which increased concurrently with the ascitic plasma volume. Amino acid transport capacity did not change in the log vs. the resting cells. This fact permitted the correction of the specific activity of the proteins synthesized by tumors in the two phases, taking into account the dilution effect. Protein synthesis was found to proceed at a constant rate throughout each of the two phases, although it was 30% lower during the resting as compared to the log phase. When cell mass attained the steady-state, protein degradation occurred at such a level as to balance the synthesis. Throughout the resting phase the amount of lysine taken up by the cells and renewed from the blood remained unchanged. Protein turnover, as studied in subcellular fractions, exhibited a similar rate in nuclei and microsomes, where it proceeded at a higher level than in mitochondria. On the whole, the results encourage the use of the Yoshida ascites hepatoma as a suitable model for studying protein turnover in relation to cell growth in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369083"}
{"pmid": "4369086", "title": "Proteolipids.", "content": "Proteolipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369086"}
{"pmid": "4369085", "title": "Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains.", "content": "Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains. The polypeptides from purified virions of a herpes simplex 1 (human herpes-virus 1) strain, F1, which had been passaged a limited number of times in cell culture after isolation, formed 33 bands on electrophoretic separation in polyacrylamide gels cross-linked with N, N'-diallyltartardiamide in contrast to a maximum resolution of only 24 to 25 bands in gels cross-linked with N, N'-methylenebisacrylamide. This increase in the number of bands was due chiefly to an improved separation of glycosylated polypeptides from nonglycosylated polypeptides with which they co-electrophoresed on methylenebisacrylamide cross-linked gels. Purified virions of HSV-1 [F1] had a protein/DNA mass ratio of 10.7 +/- 0.96, and based on a DNA molecular mass of 85 x 10(6) to 100 x 10(6) the estimated weight of virion polypeptides ranges from 16.4 to 19.4 x 10(-16) g. The number of molecules of each polypeptide per virion ranged from less than 50 to 1,500. Comparison of the virion polypeptides of two HSV-1 strains with similar isolation and limited passage history with those of four HSV-1 strains with histories of numerous passages outside the human host showed a number of nonrandom variations in virion polypeptides. Thus, although the virion polypeptides of two strains with similar isolation and limited passage history could not be differentiated, strains with extended passage histories differed markedly from each other and from the limited passage strains in the number and electrophoretic mobility of noncapsid polypeptides and notably in those of the envelope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369085"}
{"pmid": "4369084", "title": "Protein-losing enteropathy in primary lymphoedema: mesenteric lymphography and gut resection.", "content": "Protein-losing enteropathy in primary lymphoedema: mesenteric lymphography and gut resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369084"}
{"pmid": "4369090", "title": "Purification and characterization of Streptomyces sialidases.", "content": "Purification and characterization of Streptomyces sialidases. Some strains of Streptomyces produce sialidases. Two sialidases were purified over 1,000-fold from a culture filtrate of two Streptomyces species. They had the same properties in molecular weight, behavior to ions and other reagents, and substrate specificity. They showed very small differences in kinetic properties, pH optima, and heat stability. These Streptomyces sialidases differed markedly from Clostridium perfringens sialidase in molecular weight, p-chloromercuribenzoate sensitivity, and substrate specificity. Approximate molecular weights of the sialidases from Streptomyces and C. perfringens were 32,000 and 57,000, respectively. p-Chloromercuribenzoate (10(-3) M) caused complete inhibition of C. perfringens sialidase but not of Streptomyces sialidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369090"}
{"pmid": "4369094", "title": "Purification of the cAMP receptor protein by affinity chromatography.", "content": "Purification of the cAMP receptor protein by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369094"}
{"pmid": "4369093", "title": "Purification of messenger RNA and heterogeneous nuclear RNA containing poly(a) sequences.", "content": "Purification of messenger RNA and heterogeneous nuclear RNA containing poly(a) sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369093"}
{"pmid": "4369087", "title": "Psychiatric drugs and trends. Review of the phenothiazines. II.", "content": "Psychiatric drugs and trends. Review of the phenothiazines. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369087"}
{"pmid": "4369089", "title": "Psychiatric patients' impressions of teaching conferences.", "content": "Psychiatric patients' impressions of teaching conferences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369089"}
{"pmid": "4369092", "title": "Purification and regulatory properties of phosphoribulokinase from Hydrogenomonas eutropha H 16.", "content": "Purification and regulatory properties of phosphoribulokinase from Hydrogenomonas eutropha H 16. 1. Phosphoribulokinase was purified 286-fold from extracts of autotrophically grown cells. 2. The enzyme had a molecular weight of 237000 and showed a pH optimum of 9.0 in both crude extracts and purified preparation. MgCl(2) was required for activity; full activation was obtained at 5mm-MgCl(2) and the K(m) was approx. 0.5mm. 3. The ATP-saturation curve was sigmoidal and the degree of positive co-operativity increased at higher MgCl(2) concentrations. The ATP-binding sites appeared to be non-interacting at low ribulose 5-phosphate concentrations. 4. Lineweaver-Burk plots for ribulose 5-phosphate showed abrupt transitions between apparently linear sections. The apparent K(m) and V(max.) values increased with increasing concentrations of ribulose phosphate. The transitions may be explained by a sequence of negative and positive co-operativity in the catalytic rate constants. 5. Phosphoribulokinase activity was inhibited by AMP and phosphoenolpyruvate and was activated by NADH. The presence of AMP or phosphoenolpyruvate increased s(0.5) (substrate concentration required for half-maximal velocity) for both ribulose 5-phosphate and ATP but V(max.) was not changed. The sigmoidicity of the ATP-saturation curve increased in the presence of AMP but was not affected by phosphoenolpyruvate. The transitions in the ribulose 5-phosphate-saturation curves were more abrupt in the presence of either inhibitor. NADH lowered the s(0.5) for both ribulose 5-phosphate and ATP. The activator did not affect the degree of positive co-operativity between ATP-binding sites, but the ribulose 5-phosphate-binding sites appeared to be non-interacting in its presence. 6. A sequence of positive and negative co-operativity in the interactions of AMP-binding sites was suggested by the Hill plots. In the presence of NADH (and phosphoenolpyruvate) the sensitivity to inhibition by AMP was less below a certain AMP concentration and increased above that concentration. 7. Examination of the interactions between ligands indicated that phosphoribulokinase can be regulated effectively by changes in effector concentrations similar to those reported to occur in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369092"}
{"pmid": "4369095", "title": "Purification of Escherichia coli ADPglucose pyrophosphorylase by affinity chromatography.", "content": "Purification of Escherichia coli ADPglucose pyrophosphorylase by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369095"}
{"pmid": "4369097", "title": "Pyrophosphate arthropathy: a clinical study of fifty cases.", "content": "Pyrophosphate arthropathy: a clinical study of fifty cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369097"}
{"pmid": "4369091", "title": "Purification and propeties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of Pseudomonas putida.", "content": "Purification and propeties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of Pseudomonas putida. Cells of Pseudomonas putida, after growth with naphthalene as sole source of carbon and energy, contain an enzyme that oxidizes (+)-cis-1(r),2(s)-dihydroxy-1,2-dihydronaphthalene to 1,2-dihydroxynaphthalene. The purified enzyme has a molecular weight of 102,000 and apparently consists of four 25,500 molecular weight subunits. The enzyme is specific for nicotinamide adenine dinucleotide as an electron acceptor and also oxidizes several other cis-dihydrodiols. However, no enzymatic activity was observed with trans-1,2-dihydronaphthalene, or the K-region cis-dihydrodiols of carcinogenic polycyclic hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369091"}
{"pmid": "4369096", "title": "Purification of N-acetyl D-glucosamine-binding proteins by affinity chromatography.", "content": "Purification of N-acetyl D-glucosamine-binding proteins by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369096"}
{"pmid": "4369098", "title": "P430, a possible primary electron acceptor in Rhodospirillum rubrum.", "content": "P430, a possible primary electron acceptor in Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369098"}
{"pmid": "4369099", "title": "Quantitative aspects of iodothyronine binding by cytosol proteins of rat liver and kidney.", "content": "Quantitative aspects of iodothyronine binding by cytosol proteins of rat liver and kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369099"}
{"pmid": "4369088", "title": "Psychiatric nursing: facilitating the development of a helping person.", "content": "Psychiatric nursing: facilitating the development of a helping person.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369088"}
{"pmid": "4369100", "title": "Quantitative determination of bile acids and their conjugates using thin-layer chromatography and a purified 3alpha-hydroxysteroid dehydrogenase.", "content": "Quantitative determination of bile acids and their conjugates using thin-layer chromatography and a purified 3alpha-hydroxysteroid dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369100"}
{"pmid": "4369102", "title": "Rabbit intubation and halothane anesthesia.", "content": "Rabbit intubation and halothane anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369102"}
{"pmid": "4369103", "title": "Radiation treatment of intraocular cancer metastases.", "content": "Radiation treatment of intraocular cancer metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369103"}
{"pmid": "4369101", "title": "Quantum chemical study of the thermodynamics, kinetics of formation and bonding of H2CN: relevance to prebiotic chemistry.", "content": "Quantum chemical study of the thermodynamics, kinetics of formation and bonding of H2CN: relevance to prebiotic chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369101"}
{"pmid": "4369104", "title": "Radiation-killed BCG in the treatment of transplanted rat tumours.", "content": "Radiation-killed BCG in the treatment of transplanted rat tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369104"}
{"pmid": "4369105", "title": "Radiographic anatomy of normal cerebral deep medullary veins: criteria for distinguishing them from their abnormal counterparts.", "content": "Radiographic anatomy of normal cerebral deep medullary veins: criteria for distinguishing them from their abnormal counterparts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369105"}
{"pmid": "4369107", "title": "Radiologic diagnosis of carcinoma of the biliary tree.", "content": "Radiologic diagnosis of carcinoma of the biliary tree.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369107"}
{"pmid": "4369108", "title": "Rapid degradation of puromycyl peptides in hepatoma cells and reticulocytes.", "content": "Rapid degradation of puromycyl peptides in hepatoma cells and reticulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369108"}
{"pmid": "4369109", "title": "Rapid determination of estriol of pregnancy by spectrodensitometry of thin layer chromatograms.", "content": "Rapid determination of estriol of pregnancy by spectrodensitometry of thin layer chromatograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369109"}
{"pmid": "4369106", "title": "Radioimmunologic determination of plasma unconjugated estriol in normal and abnormal pregnancies with a specific antiserum to estriol.", "content": "Radioimmunologic determination of plasma unconjugated estriol in normal and abnormal pregnancies with a specific antiserum to estriol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369106"}
{"pmid": "4369111", "title": "Rapid isolation of a plant microsomal fraction by Mg2+--precipitation.", "content": "Rapid isolation of a plant microsomal fraction by Mg2+--precipitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369111"}
{"pmid": "4369112", "title": "Rapidly fatal cytomegalovirus pneumonia in Hodgkin's disease.", "content": "Rapidly fatal cytomegalovirus pneumonia in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369112"}
{"pmid": "4369110", "title": "Rapid diagnosis and typind of herpesvirus hominis by the fluorescent antibody method.", "content": "Rapid diagnosis and typind of herpesvirus hominis by the fluorescent antibody method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369110"}
{"pmid": "4369113", "title": "Rate constants for the reactions of OH radicals with the enzyme proteins as determined by the p-nitrosodimethylaniline method.", "content": "Rate constants for the reactions of OH radicals with the enzyme proteins as determined by the p-nitrosodimethylaniline method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369113"}
{"pmid": "4369114", "title": "Re-examination of the sequence of the C-terminal tryptic fragment from porcine adrenocorticotropic hormone.", "content": "Re-examination of the sequence of the C-terminal tryptic fragment from porcine adrenocorticotropic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369114"}
{"pmid": "4369116", "title": "Reaction of nucleosides with N-trimethylsilylimidazole: separation of TMS derivatives of anomeric pyrimidine nucleosides by gas-liquid chromatography.", "content": "Reaction of nucleosides with N-trimethylsilylimidazole: separation of TMS derivatives of anomeric pyrimidine nucleosides by gas-liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369116"}
{"pmid": "4369117", "title": "Reassociation and reactivation of lactic dehydrogenase from the unfolded subunits.", "content": "Reassociation and reactivation of lactic dehydrogenase from the unfolded subunits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369117"}
{"pmid": "4369119", "title": "Recent advances in wound healing.", "content": "Recent advances in wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369119"}
{"pmid": "4369115", "title": "Reaction of alantolactone, an allergenic sesquiterpene lactone, with some amino acids. Resultant loss of immunologic reactivity.", "content": "Reaction of alantolactone, an allergenic sesquiterpene lactone, with some amino acids. Resultant loss of immunologic reactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369115"}
{"pmid": "4369120", "title": "Recent views on tremors and their treatment.", "content": "Recent views on tremors and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369120"}
{"pmid": "4369122", "title": "Recombination of human erythrocyte apoprotein and lipid. I. Interaction of apoprotein and lipid at the air-water interface.", "content": "Recombination of human erythrocyte apoprotein and lipid. I. Interaction of apoprotein and lipid at the air-water interface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369122"}
{"pmid": "4369121", "title": "Receptors and acceptors: a necessary distinction in hormone binding studies.", "content": "Receptors and acceptors: a necessary distinction in hormone binding studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369121"}
{"pmid": "4369123", "title": "Recommended methods for the determination of four enzymes in blood.", "content": "Recommended methods for the determination of four enzymes in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369123"}
{"pmid": "4369118", "title": "Recent advances in glycogen metabolism.", "content": "Recent advances in glycogen metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369118"}
{"pmid": "4369125", "title": "Reduced nicotinamide adenine dinucleotide cytochrome o reductase associated with cytochrome o purified from Vitreoscilla. Evidence for an intermediate oxygenated form of cytochrome o.", "content": "Reduced nicotinamide adenine dinucleotide cytochrome o reductase associated with cytochrome o purified from Vitreoscilla. Evidence for an intermediate oxygenated form of cytochrome o.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369125"}
{"pmid": "4369126", "title": "Reduction of the pressor response to angiotensin and norepinephrine in the rat, induced by a renal peptide.", "content": "Reduction of the pressor response to angiotensin and norepinephrine in the rat, induced by a renal peptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369126"}
{"pmid": "4369128", "title": "Regulation of amino acid transport in chick embryo heart cells. IV. Site and mechanisms of insulin action.", "content": "Regulation of amino acid transport in chick embryo heart cells. IV. Site and mechanisms of insulin action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369128"}
{"pmid": "4369127", "title": "Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.", "content": "Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369127"}
{"pmid": "4369129", "title": "Regulation of cellular sterol flux and synthesis by human serum lipoproteins.", "content": "Regulation of cellular sterol flux and synthesis by human serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369129"}
{"pmid": "4369124", "title": "Recurrent herpes simplex virus infections.", "content": "Recurrent herpes simplex virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369124"}
{"pmid": "4369130", "title": "Regulation of hormone stimulation of adipose tissue lipolysis by guanosine triphosphate.", "content": "Regulation of hormone stimulation of adipose tissue lipolysis by guanosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369130"}
{"pmid": "4369131", "title": "Regulation of steroid biosynthesis.", "content": "Regulation of steroid biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369131"}
{"pmid": "4369133", "title": "Regulation of the mammalian pyruvate dehydrogenase multienzyme complex by Mg2+ and the adenine nucleotide pool.", "content": "Regulation of the mammalian pyruvate dehydrogenase multienzyme complex by Mg2+ and the adenine nucleotide pool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369133"}
{"pmid": "4369134", "title": "Relative stabilities of the intermediate reducible crosslinks present in collagen fibres.", "content": "Relative stabilities of the intermediate reducible crosslinks present in collagen fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369134"}
{"pmid": "4369132", "title": "Regulation of synthesis of two immunologically distinct nucleic acid-dependent nucleoside triphosphate phosphohydrolases in vaccinia virus-infected HeLa cells.", "content": "Regulation of synthesis of two immunologically distinct nucleic acid-dependent nucleoside triphosphate phosphohydrolases in vaccinia virus-infected HeLa cells. The two nucleic acid-dependent nucleoside triphosphate phosphohydrolases, previously purified from vaccinia virus cores, were shown to be immunologically distinct enzymes. Antiserum prepared against purified phosphohydrolase I and antiserum prepared against purified phosphohydrolase II only neutralized the activity of that enzyme used as antigen. Both enzymes were induced in HeLa cells after vaccinia infection. DNA-cellulose chromatography was used to purify the two phosphohydrolases from the cytoplasms of infected cells. The enzymes were identified by their different substrate specificities, nucleic acid dependence, and neutralization with specific antiserum. A third chromatographically separable nucleic acid-dependent phosphohydrolase similar to phosphohydrolase I in substrate specificity but not neutralizable by antiserum to either phosphohydrolase I or II, was also isolated from infected cells. No nucleic acid-dependent nucleoside triphosphate phosphohydrolase activity was detected by similar methods from uninfected HeLa cells. Formation of these virus-induced enzymes was prevented by actinomycin D and cycloheximide, indicating a requirement for de novo RNA and protein synthesis, respectively. The kinetics of induction and inhibition by cytosine arabinoside, an inhibitor of DNA synthesis, suggested that synthesis of the phosphohydrolases is a late viral function. Rifampin, an inhibitor of vaccinia virus growth which prevents virion assembly, had no inhibitory effect on the induction of the phosphohydrolases. This result was consistent with the finding that these enzymes exist in a soluble as well as in a particulate form in the cytoplasm of infected cells. Addition of another specific anti-poxviral drug, isatin-beta-thiosemicarbazone, to vaccinia-infected cells partially inhibited induction of the phosphohydrolases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369132"}
{"pmid": "4369135", "title": "Relaxation of catabolite repression and loss of valine sensitivity in Escherichia coli K-12.", "content": "Relaxation of catabolite repression and loss of valine sensitivity in Escherichia coli K-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369135"}
{"pmid": "4369137", "title": "Release of lipopolysaccharide, phospholipids and enzymes from Salmonella enteritidis by ethylenediaminetetra-acetic acid.", "content": "Release of lipopolysaccharide, phospholipids and enzymes from Salmonella enteritidis by ethylenediaminetetra-acetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369137"}
{"pmid": "4369138", "title": "Remarks about angiographic findings in cases of pontine tumor.", "content": "Remarks about angiographic findings in cases of pontine tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369138"}
{"pmid": "4369139", "title": "Renal transplantation in hypophosphatemia with vitamin D-resistant rickets.", "content": "Renal transplantation in hypophosphatemia with vitamin D-resistant rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369139"}
{"pmid": "4369136", "title": "Relaxation spectra of rabbit muscle lactate dehydrogenase and tetraiodofluorescein.", "content": "Relaxation spectra of rabbit muscle lactate dehydrogenase and tetraiodofluorescein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369136"}
{"pmid": "4369140", "title": "Renin-angiotensin-aldosterone system of a woman with Bartter's syndrome: Juxtaglomerular cell hyperplasia without hypertension.", "content": "Renin-angiotensin-aldosterone system of a woman with Bartter's syndrome: Juxtaglomerular cell hyperplasia without hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369140"}
{"pmid": "4369141", "title": "Reovirus-associated mortality in broiler chickens.", "content": "Reovirus-associated mortality in broiler chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369141"}
{"pmid": "4369143", "title": "Replication of mouse-tropic and xenotropic strains of murine leukemia virus in human x mouse hybrid cells.", "content": "Replication of mouse-tropic and xenotropic strains of murine leukemia virus in human x mouse hybrid cells. The replication of mouse-tropic and xenotropic strains of murine leukemia virus in human x mouse hybrid cells was investigated. NB-tropic strains of the leukemia virus replicated efficiently in several hybrid lines, including those that contained a complete complement of human chromosomes and many mouse chromosomes. In lines with only a few mouse chromosomes, NB-tropic viruses failed to replicate. N- and B-tropic viruses replicated in human x N-type and human x B-type cells, respectively. The N- and B-tropic viruses replicating in these hybrid cells retained their original tropism. The viral restrictive functions of the mouse Fv-1 locus were expressed in the hybrid cells, restricting the replication of N- and B-tropic strains in human x B-type and human x N-type mouse cells, respectively. In contrast to mouse-tropic viruses, AT-124 virus, a xenotropic strain, replicated in human but not in mouse cells or in hybrid cells containing a complete complement of human chromosomes and near complete complement of mouse chromosomes However, hybrid lines with only a few mouse chromosomes supported AT-124 replication. Thus, human genes in hybrid cells do not restrict the replication of mouse or xenotropic murine leukemia virus strains, while mouse genes in such cells restrict xenotropic leukemia virus replication and, as determined by the mouse Fv-1 phenotype, mouse-tropic murine leukemia virus. These results indicate that exogenously applied mouse-tropic and xenotropic oncornaviruses exhibit different patterns of restriction in human-mouse hybrid cells and that such hybrid cells may be used for genetic analysis of oncornavirus replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369143"}
{"pmid": "4369142", "title": "Replacement of ribothymidine by 5-methyl-2-thiouridine in sequence GT psi C in tRNA of an extreme thermophile.", "content": "Replacement of ribothymidine by 5-methyl-2-thiouridine in sequence GT psi C in tRNA of an extreme thermophile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369142"}
{"pmid": "4369144", "title": "Requirement for cell division for initiation of transcription of Rous sarcoma virus RNA.", "content": "Requirement for cell division for initiation of transcription of Rous sarcoma virus RNA. Stationary chicken embryo fibroblasts exposed to Rous sarcoma virus (RSV) did not synthesize virus RNA until after division of the infected cells. Initiation of RNA transcription after cell division resulted in transcription of the entire viral genome and was followed shortly thereafter by appearance of progeny virus. Addition of colchicine to RSV-infected stationary chicken embryo fibroblasts resulted in inhibition of cell division and a 24-h delay in the appearance of virus RNA. RSV-infected chicken embryo fibroblasts made stationary 10 to 15 cell generations after infection continued to produce an amount of progeny virus similar to that produced in dividing RSV-infected cells. Teh virus produced from cells made stationary after virus production had begun contained RNA synthesized in stationary cells. Therefore, division of the RSV-infected chicken embryo fibroblast is required for the initiation of transcription of virus RNA, but it is not required for the maintenance of transcription of virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369144"}
{"pmid": "4369145", "title": "Requirement of L-serine for enzymic activation of carcinogen, 4-hydroxyaminoquinoline 1-oxide.", "content": "Requirement of L-serine for enzymic activation of carcinogen, 4-hydroxyaminoquinoline 1-oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369145"}
{"pmid": "4369146", "title": "Respiratory deficiency in Saccharomyces carlsbergensis 4228 caused by thiamine and its prevention by pyridoxine.", "content": "Respiratory deficiency in Saccharomyces carlsbergensis 4228 caused by thiamine and its prevention by pyridoxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369146"}
{"pmid": "4369148", "title": "Retinoblastoma in Norway.", "content": "Retinoblastoma in Norway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369148"}
{"pmid": "4369147", "title": "Reticuloendothelial function in experimental injury and tolerance to shock.", "content": "Reticuloendothelial function in experimental injury and tolerance to shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369147"}
{"pmid": "4369149", "title": "Retrospective study of 117 patients with optic neuritis.", "content": "Retrospective study of 117 patients with optic neuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369149"}
{"pmid": "4369150", "title": "Ribonucleoprotein complexes containing nascent DNA-like RNA in the crude chromatin fraction of rat liver.", "content": "Ribonucleoprotein complexes containing nascent DNA-like RNA in the crude chromatin fraction of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369150"}
{"pmid": "4369151", "title": "Rod outer segment phosphodiesterase: factors affecting the hydrolysis of cyclic-AMP and cyclic-GMP.", "content": "Rod outer segment phosphodiesterase: factors affecting the hydrolysis of cyclic-AMP and cyclic-GMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369151"}
{"pmid": "4369152", "title": "Role of cyclic nucleotides in cancer.", "content": "Role of cyclic nucleotides in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369152"}
{"pmid": "4369153", "title": "Role of cyclic AMP in reproductive processes.", "content": "Role of cyclic AMP in reproductive processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369153"}
{"pmid": "4369154", "title": "Role of vasopressin and angiotensin in response of splanchnic resistance vessels to hemorrhage.", "content": "Role of vasopressin and angiotensin in response of splanchnic resistance vessels to hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369154"}
{"pmid": "4369155", "title": "Rorschach responses subsequent to REM deprivation in schizophrenic and nonschizophrenic patients.", "content": "Rorschach responses subsequent to REM deprivation in schizophrenic and nonschizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369155"}
{"pmid": "4369156", "title": "Sabin's vaccine used for nonspecific prevention of infant diarrhea of viral etiology.", "content": "Sabin's vaccine used for nonspecific prevention of infant diarrhea of viral etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369156"}
{"pmid": "4369157", "title": "Salmonellosis and shigellosis at Boston City Hospital. 2. Susceptibility of strains of Salmonellae and Shigellae to antibacterial agents.", "content": "Salmonellosis and shigellosis at Boston City Hospital. 2. Susceptibility of strains of Salmonellae and Shigellae to antibacterial agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369157"}
{"pmid": "4369158", "title": "Seasonal infection of Culex mosquitos and swine with Japanese encephalitis virus.", "content": "Seasonal infection of Culex mosquitos and swine with Japanese encephalitis virus. A year-round study of the infection rates of JE virus in Culex mosquitos was made during 1970-71 in 2 hamlets in Taoyuan County, China (Province of Taiwan). JE virus was recovered from 5 of 314 pools of C. annulus, and from 1 of 22 pools of C. tritaeniorhynchus; these recoveries occurred during a 14-day period in July 1971. None of the 288 pools of C. p. fatigans, which had been collected between October and April, was positive. In addition, sentinel swine were assessed for antibody and virus. All the pigs became highly immune by 23 July; in each hamlet all the pigs had become infected within 1 week, virus being detected in them for only 1-2 weeks. Virus-positive mosquitos appeared to have obtained their infections at about the time that viraemia was occurring in the sentinel swine. These observations illustrate once again the lower infection rate and shorter duration of virus-positive mosquitos in China (Province of Taiwan) as compared with Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369158"}
{"pmid": "4369159", "title": "Secretion of apolipoproteins in very low density and high density lipoproteins by perfused rat liver.", "content": "Secretion of apolipoproteins in very low density and high density lipoproteins by perfused rat liver. The incorporation of labeled amino acids into the peptides of very low density lipoproteins (VLDL) and high density lipoproteins (HDL) secreted by perfused rat liver was studied using a Ringer-albumin solution in the perfusate in place of serum to diminish exchange of peptides between VLDL and HDL. Among the lipoproteins, the greatest release of protein, greatest incorporation of amino acid, and highest specific activity were found in VLDL. After separation of the delipidated peptides by electrophoresis on polyacrylamide gel, the incorporation into VLDL peptides was found to be 5-10 times as great as into HDL peptides. There was virtually no incorporation into the peptides of low density lipoproteins (LDL). Approximately 25% of the radioactivity incorporated into perfusate VLDL failed to enter the 13% polyacrylamide gel. The remaining radioactivity was distributed primarily among three peptide bands; one, found in the upper portion of the gel, contained 45% of the total, most of the remainder being found in two rapidly migrating bands. These three peptides appear to approximate those of human apo-C in relative electrophoretic mobility. Most of the HDL peptide radioactivity entering the running gel was found in a band that migrates slightly faster than the main VLDL band. A portion of the radioactivity of this major HDL band did not enter the running gel unless beta-mercaptoethanol was present. Greater separation of these two bands by polyacrylamide gel electrophoresis for 24 hr confirmed that the major bands in VLDL and in HDL were different. The rapidly moving peptides of HDL were found to contain very little radioactivity. Determination of the intensity of staining of carrier-free perfusate VLDL and HDL peptides produced a pattern similar to the incorporation of labeled amino acids. It is concluded that the rapidly moving peptides, which may contain activators of lipoprotein lipase, are only secreted as part of the VLDL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369159"}
{"pmid": "4369160", "title": "Selection and application of factors for forecasting the epidemic time and severity of Japanese encephalitis prevalence.", "content": "Selection and application of factors for forecasting the epidemic time and severity of Japanese encephalitis prevalence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369160"}
{"pmid": "4369161", "title": "Selective formation of desmosomes in chick cell reaggregates.", "content": "Selective formation of desmosomes in chick cell reaggregates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369161"}
{"pmid": "4369162", "title": "Semen matrix calculi in a rhesus monkey (Macaca mulatta).", "content": "Semen matrix calculi in a rhesus monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369162"}
{"pmid": "4369163", "title": "Separate estimation of serum beta-lipoprotein cholesterol and pre-beta-lipoprotein cholesterol: clinical aspects.", "content": "Separate estimation of serum beta-lipoprotein cholesterol and pre-beta-lipoprotein cholesterol: clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369163"}
{"pmid": "4369165", "title": "Separation of urinary androstanediol and pregnanediol isomers by a combined gas-liquid chromatography-thin-layer chromatography method.", "content": "Separation of urinary androstanediol and pregnanediol isomers by a combined gas-liquid chromatography-thin-layer chromatography method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369165"}
{"pmid": "4369164", "title": "Separation of the main lipoprotein density classes from human plasma by rate-zonal ultracentrifugation.", "content": "Separation of the main lipoprotein density classes from human plasma by rate-zonal ultracentrifugation. The major lipoprotein density classes (chylomicrons-VLDL, LDL, HDL(2) and HDL(3)) were isolated from human plasma in a two-step ultracentrifugal procedure using the Ti-14 zonal rotor. The isolation of the two major high density lipoprotein subclasses (HDL(2) and HDL(3)) was achieved in a 24-hr run using a nonlinear NaBr gradient in the density range of 1.00-1.40. The lipoproteins with a density < 1.063 found in the rotor's center were isolated in a second run of 140 min duration using a continuous linear NaBr gradient in the density range of 1.00-1.30. The isolated lipoproteins were analyzed for chemical composition and for electrophoretic mobility; purity of isolated fractions was checked by immunochemistry. The lipoproteins exhibited flotation rates, chemical compositions, and molecular weights similar to those found with the common sequential procedures in angle-head rotors. The amount of lipoprotein lipids in the bottom fraction of the zonal rotor was comparable to that of the angle-head rotor. The described method yields the main lipoprotein density classes free from albumin in a very short running time; compared with the rate-zonal techniques already in use, this method allows the quantitative separation of an additional lipoprotein density class (HDL(2)) without increasing the running time. Furthermore, this procedure proved to be suitable for isolation of plasma lipoproteins from subjects with various types and varying degrees of hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369164"}
{"pmid": "4369166", "title": "Sequence dependent deamidation rates for model peptides of cytochrome C.", "content": "Sequence dependent deamidation rates for model peptides of cytochrome C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369166"}
{"pmid": "4369167", "title": "Serologic testing of various primate species maintained in a single outdoor breeding colony.", "content": "Serologic testing of various primate species maintained in a single outdoor breeding colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369167"}
{"pmid": "4369168", "title": "Serum hormone concentrations in ruminants during mammary growth, lactogenesis, and lactation: a review.", "content": "Serum hormone concentrations in ruminants during mammary growth, lactogenesis, and lactation: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369168"}
{"pmid": "4369169", "title": "Serum parathyroid hormone concentrations in hypophosphataemic vitamin D resistant rickets.", "content": "Serum parathyroid hormone concentrations in hypophosphataemic vitamin D resistant rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369169"}
{"pmid": "4369170", "title": "Significance of respiratory virus isolations. A study in primary schoolchildren.", "content": "Significance of respiratory virus isolations. A study in primary schoolchildren.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369170"}
{"pmid": "4369173", "title": "Simultaneous bilateral fluorescein angiography of the anterior eye.", "content": "Simultaneous bilateral fluorescein angiography of the anterior eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369173"}
{"pmid": "4369172", "title": "Simple methods of preparing nicotinamide mononucleotide.", "content": "Simple methods of preparing nicotinamide mononucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369172"}
{"pmid": "4369171", "title": "Simian herpesviruses and neoplasia.", "content": "Simian herpesviruses and neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369171"}
{"pmid": "4369174", "title": "Single dose irradiation in treatment of cerebral metastases from bronchial carcinoma.", "content": "Single dose irradiation in treatment of cerebral metastases from bronchial carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369174"}
{"pmid": "4369176", "title": "Sleep disorders. Recent findings in the diagnosis and treatment of disturbed sleep.", "content": "Sleep disorders. Recent findings in the diagnosis and treatment of disturbed sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369176"}
{"pmid": "4369179", "title": "Sleeping pills and dream content.", "content": "Sleeping pills and dream content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369179"}
{"pmid": "4369178", "title": "Sleep-wakefulness cycle in adult rats suffered from icterus gravis neonatorum.", "content": "Sleep-wakefulness cycle in adult rats suffered from icterus gravis neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369178"}
{"pmid": "4369180", "title": "Smallpox.", "content": "Smallpox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369180"}
{"pmid": "4369175", "title": "Sleep and some psychoactive drugs.", "content": "Sleep and some psychoactive drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369175"}
{"pmid": "4369181", "title": "So-called\"virus-like\" intranuclear filaments in brain autopsy material: a reappraisal on hand of two fatal cases of tick-borne encephalitis.", "content": "So-called\"virus-like\" intranuclear filaments in brain autopsy material: a reappraisal on hand of two fatal cases of tick-borne encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369181"}
{"pmid": "4369183", "title": "Soluble gonadotropin receptors of the rat ovary.", "content": "Soluble gonadotropin receptors of the rat ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369183"}
{"pmid": "4369177", "title": "Sleep pattern and intelligence in functional mental retardation.", "content": "Sleep pattern and intelligence in functional mental retardation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369177"}
{"pmid": "4369182", "title": "Sodium-potassium-activated adenosine triphosphatase (NaK-ATPase) activity in the rat lens. A histochemical and biochemical study.", "content": "Sodium-potassium-activated adenosine triphosphatase (NaK-ATPase) activity in the rat lens. A histochemical and biochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369182"}
{"pmid": "4369185", "title": "Some aspects on nervous control of aqueous humour dynamics in the rabbit eye.", "content": "Some aspects on nervous control of aqueous humour dynamics in the rabbit eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369185"}
{"pmid": "4369184", "title": "Soluble lymphocytic mediators. I. Inhibition of macrophage migration inhibitory factor production by drugs.", "content": "Soluble lymphocytic mediators. I. Inhibition of macrophage migration inhibitory factor production by drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369184"}
{"pmid": "4369186", "title": "Some characteristics of corticosterone uptake by the dorsal hippocampus and the adenohypophysis in the rat.", "content": "Some characteristics of corticosterone uptake by the dorsal hippocampus and the adenohypophysis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369186"}
{"pmid": "4369187", "title": "Some chemical parameters of serum, cerebrospinal fluid, perilymph, and aqueous humor of the chinchilla.", "content": "Some chemical parameters of serum, cerebrospinal fluid, perilymph, and aqueous humor of the chinchilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369187"}
{"pmid": "4369189", "title": "Some histochemical reactions in the neurocytes of the trigeminal ganglion in rabbits.", "content": "Some histochemical reactions in the neurocytes of the trigeminal ganglion in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369189"}
{"pmid": "4369191", "title": "Some properties of endothelial cells isolated from human umbilical cord vein.", "content": "Some properties of endothelial cells isolated from human umbilical cord vein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369191"}
{"pmid": "4369190", "title": "Some parasitic and other natural diseases of the African elephant in the Kruger National Park.", "content": "Some parasitic and other natural diseases of the African elephant in the Kruger National Park.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369190"}
{"pmid": "4369193", "title": "Some reactions of 1,6-di-O-p-tolylsulphonyl-D-mannitol and its derivatives.", "content": "Some reactions of 1,6-di-O-p-tolylsulphonyl-D-mannitol and its derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369193"}
{"pmid": "4369192", "title": "Some properties of the nitrogenase proteins from Clostridium pasteurianum. Molecular weight, subunit structure, isoelectric point and EPR spectra.", "content": "Some properties of the nitrogenase proteins from Clostridium pasteurianum. Molecular weight, subunit structure, isoelectric point and EPR spectra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369192"}
{"pmid": "4369194", "title": "Some studies of adrenal suppression by alternate-day prednisone therapy.", "content": "Some studies of adrenal suppression by alternate-day prednisone therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369194"}
{"pmid": "4369195", "title": "Spacer arms in affinity chromatography: use of hydrophilic arms to control or eliminate nonbiospecific adsorption effects.", "content": "Spacer arms in affinity chromatography: use of hydrophilic arms to control or eliminate nonbiospecific adsorption effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369195"}
{"pmid": "4369197", "title": "Specific inactivation of fructose 1,6-bisphosphatase from Saccharomyces cerevisiae by a yeast protease.", "content": "Specific inactivation of fructose 1,6-bisphosphatase from Saccharomyces cerevisiae by a yeast protease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369197"}
{"pmid": "4369200", "title": "Specific RNA fragments in defective particles of bacteriophage MS2.", "content": "Specific RNA fragments in defective particles of bacteriophage MS2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369200"}
{"pmid": "4369199", "title": "Specific interaction of 3H-FSH with rat testis binding sites.", "content": "Specific interaction of 3H-FSH with rat testis binding sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369199"}
{"pmid": "4369202", "title": "Specificity of the retrograde axonal transport of nerve growth factor.", "content": "Specificity of the retrograde axonal transport of nerve growth factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369202"}
{"pmid": "4369203", "title": "Spectral characteristics and interconversions of the reduced oxidized, and oxygenated forms of purified cytochrome o.", "content": "Spectral characteristics and interconversions of the reduced oxidized, and oxygenated forms of purified cytochrome o.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369203"}
{"pmid": "4369201", "title": "Specificity of the natural rat liver ribonuclease inhibitor towards nuclease activities of subcellular fractions.", "content": "Specificity of the natural rat liver ribonuclease inhibitor towards nuclease activities of subcellular fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369201"}
{"pmid": "4369204", "title": "Spin labelling of D-glyceraldehyde-3-phosphate dehydrogenase with specific reagents.", "content": "Spin labelling of D-glyceraldehyde-3-phosphate dehydrogenase with specific reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369204"}
{"pmid": "4369205", "title": "Spin-labeled polyuridylic acid. Formation of an intermediate structure.", "content": "Spin-labeled polyuridylic acid. Formation of an intermediate structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369205"}
{"pmid": "4369206", "title": "Spin-labelled phosphorylase as a probe in a rabbit muscle glycogen particle fraction.", "content": "Spin-labelled phosphorylase as a probe in a rabbit muscle glycogen particle fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369206"}
{"pmid": "4369196", "title": "Speaking out on: social change, social policy and the helping professional.", "content": "Speaking out on: social change, social policy and the helping professional.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369196"}
{"pmid": "4369207", "title": "Splenomegaly, sex, and other characteristics of laboratory animals used for primary isolations of Coxiella burnetii.", "content": "Splenomegaly, sex, and other characteristics of laboratory animals used for primary isolations of Coxiella burnetii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369207"}
{"pmid": "4369209", "title": "Spontaneous hematoma of the optic chiasma. Report of a case.", "content": "Spontaneous hematoma of the optic chiasma. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369209"}
{"pmid": "4369208", "title": "Spontaneous and stimulated secretion of QUSO-extractable immunoassayable ACTH in man.", "content": "Spontaneous and stimulated secretion of QUSO-extractable immunoassayable ACTH in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369208"}
{"pmid": "4369198", "title": "Specific inhibition of the renin-angiotensin system: A key to understanding blood pressure regulation.", "content": "Specific inhibition of the renin-angiotensin system: A key to understanding blood pressure regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369198"}
{"pmid": "4369210", "title": "Spontaneous tumours of the central nervous system of laboratory rats.", "content": "Spontaneous tumours of the central nervous system of laboratory rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369210"}
{"pmid": "4369211", "title": "Steroid metabolism in arrhenoblastoma.", "content": "Steroid metabolism in arrhenoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369211"}
{"pmid": "4369212", "title": "Steroid-induced bilateral femoral head ischaemic necrosis.", "content": "Steroid-induced bilateral femoral head ischaemic necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369212"}
{"pmid": "4369214", "title": "Stimulation of a dopamine-sensitive adenylate cyclase in homogenates of rat striatum by a metabolite of piribedil (ET 495).", "content": "Stimulation of a dopamine-sensitive adenylate cyclase in homogenates of rat striatum by a metabolite of piribedil (ET 495).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369214"}
{"pmid": "4369213", "title": "Stimulation by D-glucose of cyclic adenosine 3':5'-monophosphate accumulation and insulin release in isolated pancreatic islets of the rat.", "content": "Stimulation by D-glucose of cyclic adenosine 3':5'-monophosphate accumulation and insulin release in isolated pancreatic islets of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369213"}
{"pmid": "4369215", "title": "Stimulation of melanogenesis in cultured melanoma cells by calciferols.", "content": "Stimulation of melanogenesis in cultured melanoma cells by calciferols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369215"}
{"pmid": "4369216", "title": "Stimulation of sodium transport in turkey erythrocytes by cyclic 3',5'-AMP.", "content": "Stimulation of sodium transport in turkey erythrocytes by cyclic 3',5'-AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369216"}
{"pmid": "4369217", "title": "Streptozotocin diabetes. Correlation with extent of depression of pancreatic islet nicotinamide adenine dinucleotide.", "content": "Streptozotocin diabetes. Correlation with extent of depression of pancreatic islet nicotinamide adenine dinucleotide. The diabetogenic activity of streptozotocin has been correlated with a reduction in pyridine nucleotide synthesis in the mouse pancreatic islet. To determine the specificity of this reduction for diabetogenicity, a comparative study of streptozotocin, its cytotoxic moiety, 1-methyl-1-nitrosourea, and alloxan was performed. Streptozotocin administered intraperitoneally (i.p.) producd a dose-related reduction in islet NAD which was proportional to the degree of diabetogenicity. A diabetogenic dose, 200 mg/kg, attained a peak plasma N-nitroso intact streptozotocin concentration of 0.224 mumol/ml and reduced the mean islet NAD from a control of 0.78 to 0.15 pmol. At borderline, 150 mg/kg, and nondiabetogenic, 100 mg/kg, doses, plasma concentrations reached 0.161 and 0.136 mumol/ml, and NAD was 0.36 and 0.86 pmol/islet, respectively. 1-Methyl-1-nitrosourea, 100 mg/kg, attained a maximum N-nitroso intact 1-methyl-1-nitrosourea concentration of 0.162 mumol/ml and reduced the mean NAD to 0.58 pmol/islet, and was nondiabetogenic; 200 mg/kg attained a peak plasma concentration of 0.344 mumol/ml and depressed NAD to 0.38 pmol/islet, and was inconsistently diabetogenic. Islet NAD of 0.4 pmol/islet or greater is required for integrity of the beta cell. A diabetogenic dose of alloxan, 500 mg/kg, did not depress NAD, 0.85 pmol/islet, therefore confirming that its mechanism of diabetogenicity differs from that of streptozotocin. In vivo uptake of [methyl-(14)C]streptozotocin by islets was 3.8 times that of [methyl-(14)C]-1-methyl-1-nitrosourea, whereas uptake by the exocrine pancreas favored 1-methyl-1-nitrosourea over streptozotocin 2.4:1. The decreased islet uptake of 1-methyl-1-nitrosourea correlates with the 3.5 times increased molar dosage required to produce islet NAD depression comparable to that of streptozotocin, 150 mg/kg. These studies indicate that the glucose carrier of streptozotocin facilitates uptake of its cytotoxic group, 1-methyl-1-nitrosourea, into islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369217"}
{"pmid": "4369218", "title": "Structural and functional changes in human and experimental neuropathy.", "content": "Structural and functional changes in human and experimental neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369218"}
{"pmid": "4369220", "title": "Structural studies of a mitochondria-free plasma membrane fraction from rat liver.", "content": "Structural studies of a mitochondria-free plasma membrane fraction from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369220"}
{"pmid": "4369221", "title": "Structure of bis(methylguanidinium) monohydrogen orthophosphate. A model for the arginine-phosphate interactions at the active site of staphylococcal nuclease and other phosphohydrolytic enzymes.", "content": "Structure of bis(methylguanidinium) monohydrogen orthophosphate. A model for the arginine-phosphate interactions at the active site of staphylococcal nuclease and other phosphohydrolytic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369221"}
{"pmid": "4369219", "title": "Structural membrane proteins and loosely associated proteins of the sarcoplasmic reticulum.", "content": "Structural membrane proteins and loosely associated proteins of the sarcoplasmic reticulum. The protein composition of sarcoplasmic-reticulum vesicles, either unpurified or after fractionation on sucrose gradients, and with or without previous osmotic shock and sonication, was investigated by electrophoresis in acid polyacrylamide gels. The pattern of release of loosely bound proteins is discussed with respect to their localization in the interior of the vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369219"}
{"pmid": "4369188", "title": "Some fundamental considerations in the study of sleep.", "content": "Some fundamental considerations in the study of sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369188"}
{"pmid": "4369222", "title": "Structure-function relationship in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase. Trinitrophenylation of the lysine residues.", "content": "Structure-function relationship in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase. Trinitrophenylation of the lysine residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369222"}
{"pmid": "4369223", "title": "Structure-function relationships in foot-and-mouth disease virus.", "content": "Structure-function relationships in foot-and-mouth disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369223"}
{"pmid": "4369225", "title": "Studies of insulin, growth hormone and prolactin binding: tissue distribution, species variation and characterization.", "content": "Studies of insulin, growth hormone and prolactin binding: tissue distribution, species variation and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369225"}
{"pmid": "4369224", "title": "Studies of insulin, growth hormone and prolactin binding: ontogenesis, effects of sex and pregnancy.", "content": "Studies of insulin, growth hormone and prolactin binding: ontogenesis, effects of sex and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369224"}
{"pmid": "4369227", "title": "Studies on androgen and estrogen uptake by rat hypothalamus.", "content": "Studies on androgen and estrogen uptake by rat hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369227"}
{"pmid": "4369228", "title": "Studies on free and 5 S RNA-bound ribosomal GTPase and ATPase.", "content": "Studies on free and 5 S RNA-bound ribosomal GTPase and ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369228"}
{"pmid": "4369226", "title": "Studies of the polysaccharide fraction from the lipopolysaccharide of Pseudomonas alcaligenes.", "content": "Studies of the polysaccharide fraction from the lipopolysaccharide of Pseudomonas alcaligenes. Studies of the lipopolysaccharide of Pseudomonas alcaligenes strain BR 1/2 were extended to the polysaccharide moiety. The crude polysaccharide, obtained by mild acid hydrolysis of the lipopolysaccharide, was fractionated by gel filtration. The major fraction was the phosphorylated polysaccharide, for which the approximate proportions of residues were; glucose (2), rhamnose (0.7), heptose (2-3), galactosamine (1), alanine (1), 3-deoxy-2-octulonic acid (1), phosphorus (5-6). The heptose was l-glycero-d-manno-heptose. The minor fractions from gel filtration contained free 3-deoxy-2-octulonic acid, P(i) and PP(i). The purified polysaccharide was studied by periodate oxidation, methylation analysis, partial hydrolysis, and dephosphorylation. All the rhamnose and part of the glucose and heptose occur as non-reducing terminal residues. Other glucose residues are 3-substituted, and most heptose residues are esterified with condensed phosphate residues, possibly in the C-4 position. Free heptose and a heptosylglucose were isolated from a partial hydrolysate of the polysaccharide. The location of galactosamine in the polysaccharide was not established, but either the C-3 or C-4 position appears to be substituted and a linkage to alanine was indicated. In its composition, the polysaccharide from Ps. alcaligenes resembles core polysaccharides from other pseudomonads: no possible side-chain polysaccharide was detected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369226"}
{"pmid": "4369231", "title": "Studies on pyrimidine biosynthesis in the granulocytes of patients receiving gold therapy for rheumatoid arthritis.", "content": "Studies on pyrimidine biosynthesis in the granulocytes of patients receiving gold therapy for rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369231"}
{"pmid": "4369229", "title": "Studies on polynucleotides. The linkage of deoxyribopolynucleotide templates to cellulose and its use in their replication.", "content": "Studies on polynucleotides. The linkage of deoxyribopolynucleotide templates to cellulose and its use in their replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369229"}
{"pmid": "4369230", "title": "Studies on proteins of animal ribosomes. XVII. Quantitative aspects of enzymatic phosphorylation of ribosomal proteins and particles from rat liver.", "content": "Studies on proteins of animal ribosomes. XVII. Quantitative aspects of enzymatic phosphorylation of ribosomal proteins and particles from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369230"}
{"pmid": "4369232", "title": "Studies on the biology of the lung mite, Pneumonyssus simicola banks (Acarina: Halarachnidae) and diagnosis of infestation in macaques.", "content": "Studies on the biology of the lung mite, Pneumonyssus simicola banks (Acarina: Halarachnidae) and diagnosis of infestation in macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369232"}
{"pmid": "4369233", "title": "Studies on the control of development. Differences in the pattern of DNA binding proteins isolated from vegetative and sporulating cells of Bacillus subtilis.", "content": "Studies on the control of development. Differences in the pattern of DNA binding proteins isolated from vegetative and sporulating cells of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369233"}
{"pmid": "4369235", "title": "Studies on the estrogen receptor in breast cancer.", "content": "Studies on the estrogen receptor in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369235"}
{"pmid": "4369234", "title": "Studies on the distribution of urea cycle enzymes in different regions of rat brain.", "content": "Studies on the distribution of urea cycle enzymes in different regions of rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369234"}
{"pmid": "4369236", "title": "Studies on the immune response and pathogenesis of Sendai virus infection of mice. II. The immunoglobulin class of plasma cells in the bronchial sub-mucosa.", "content": "Studies on the immune response and pathogenesis of Sendai virus infection of mice. II. The immunoglobulin class of plasma cells in the bronchial sub-mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369236"}
{"pmid": "4369237", "title": "Studies on the interaction of concanavalin A with major density classes of human plasma lipoproteins. Evidence for the specific binding of lipoprotein B in its associated and free forms.", "content": "Studies on the interaction of concanavalin A with major density classes of human plasma lipoproteins. Evidence for the specific binding of lipoprotein B in its associated and free forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369237"}
{"pmid": "4369238", "title": "Studies on the minor components of the organic matrix of human dentine.", "content": "Studies on the minor components of the organic matrix of human dentine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369238"}
{"pmid": "4369239", "title": "Studies on the phosphorylation of nucleolar proteins. Identification of a nucleolus-associated protein kinase activity.", "content": "Studies on the phosphorylation of nucleolar proteins. Identification of a nucleolus-associated protein kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369239"}
{"pmid": "4369240", "title": "Studies on the ultrastructure of the blood-aqueous barrier in the rabbit.", "content": "Studies on the ultrastructure of the blood-aqueous barrier in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369240"}
{"pmid": "4369241", "title": "Studies on 14C-imipramine metabolism in the isolated perfused rat liver.", "content": "Studies on 14C-imipramine metabolism in the isolated perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369241"}
{"pmid": "4369242", "title": "Studies with foot-and-mouth disease virus in British deer (red, fallow and roe).", "content": "Studies with foot-and-mouth disease virus in British deer (red, fallow and roe).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369242"}
{"pmid": "4369243", "title": "Studies with foot-and-mouth disease virus in British deer (red, fallow and roe). II. Recovery of virus and serological response.", "content": "Studies with foot-and-mouth disease virus in British deer (red, fallow and roe). II. Recovery of virus and serological response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369243"}
{"pmid": "4369244", "title": "Study of the reactions of blood with artificial surfaces. Use of the thrombogenerator.", "content": "Study of the reactions of blood with artificial surfaces. Use of the thrombogenerator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369244"}
{"pmid": "4369245", "title": "Subacute sclerosing panencephalitis (SSPE). Reappraisal of nuclear, cytoplasmic and axonal inclusions ultrastructural study of eight cases.", "content": "Subacute sclerosing panencephalitis (SSPE). Reappraisal of nuclear, cytoplasmic and axonal inclusions ultrastructural study of eight cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369245"}
{"pmid": "4369246", "title": "Subcellular distribution of sphingomyelinase and other acid hydrolases in different parts of the calf lens.", "content": "Subcellular distribution of sphingomyelinase and other acid hydrolases in different parts of the calf lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369246"}
{"pmid": "4369247", "title": "Substructure of amphibian motor end plate. Evidence for a granular component projecting from the outer surface of the receptive membrane.", "content": "Substructure of amphibian motor end plate. Evidence for a granular component projecting from the outer surface of the receptive membrane. End-plate membrane has been examined at amphibian myoneural junctions by means of transmission electron microscopy of thin tissue sections. The postjunctional membrane exhibits morphologically specialized dense, convex patches which are located superficially facing the axon terminal but do not extend into the depths of the junctional folds. In the specialized regions the plasma membrane is approximately 120 A thick and trilaminar. The outer dense lamina is thickened by the presence in it of granular elements approximately 60-120 A in diameter which are spaced semiregularly at approximately 100-150-A intervals and which border the junctional cleft directly. In these regions the concentration of the granules is of the order of approximately 10(4)/microm(2), which is in the same range as the estimated concentration of receptor sites at other vertebrate cholinergic junctions. Filamentous projections can sometimes be seen extending from the granules to the overlying basement membrane, and in oblique views a reticular pattern may appear both in these patches and in the basement membrane. The cytoplasmic surface of the specialized membrane is covered with an amorphous and filamentous dense material whose distribution coincides with that of the granules visible in the outer layer and which may be connected to them across the membrane. In unosmicated specimens stained with permanganate and uranyl acetate the specialized regions exhibit the same morphological features but stand out sharply in contrast to adjacent areas of unspecialized membrane which appear only faintly. Such preparations are particularly useful in assessing the extent of the specialized membrane. It is proposed that the granules visible at the outer surface of the end-plate membrane represent acetylcholine receptors and that in amphibians, as in annelids, the receptors at myoneural junctions are concentrated into patches which occupy less than the total postjunctional membrane surface area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369247"}
{"pmid": "4369248", "title": "Subunit structure of testicular hyaluronidase.", "content": "Subunit structure of testicular hyaluronidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369248"}
{"pmid": "4369249", "title": "Sugar catabolism in Aquaspirillum gracile.", "content": "Sugar catabolism in Aquaspirillum gracile. Aquaspirillum (Spirillum) gracile is one of the few spirilla that cause acidification of the medium when cultured with sugars. Acidic reactions have been reported only for d-glucose, d-galactose, and l-arabinose, and the mode of attack of these sugars has not been previously investigated. The soluble portion of extracts of glucose-cultured cells of A. gracile ATCC 19624 was found by spectrophotometric methods to contain enzyme activities characteristic of the Entner-Doudoroff and Embden-Meyerhof-Parnas pathways. No activity for 6-phosphogluconate dehydrogenase (EC 1.1.1.44) was detected. Pyridine nucleotide-linked dehydrogenase activities for l-arabinose and d-galactose (EC 1.1.1.46 and EC 1.1.1.48) occurred in the soluble fraction of cells cultured with either sugar. Glucose-cultured cells contained not only glucokinase (EC 2.7.1.2) and glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activities but also glucose dehydrogenase (EC 1.1.1.47) activity. Enzymes capable of oxidizing gluconate were not detectable, but gluconokinase (EC 2.7.1.12) activity was present. Paper chromatographic analysis of the spent culture supernatant media from glucose-cultured cells indicated an accumulation of gluconic acid, and this was confirmed by enzymatic methods. Evidence is presented for the production of d-galactonic and l-arabonic acids in cultures containing d-galactose or l-arabinose, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369249"}
{"pmid": "4369250", "title": "Superoxide dismutase activity in WI-38 cell cultures: effects of age, trypsinization and SV-40 transformation.", "content": "Superoxide dismutase activity in WI-38 cell cultures: effects of age, trypsinization and SV-40 transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369250"}
{"pmid": "4369251", "title": "Surface glycosyltransferases on cultured mouse fibroblasts.", "content": "Surface glycosyltransferases on cultured mouse fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369251"}
{"pmid": "4369252", "title": "Survival of Entamoeba and related Amoebae at low temperature. I. Viability of Entamoeba cysts at 4 degrees C.", "content": "Survival of Entamoeba and related Amoebae at low temperature. I. Viability of Entamoeba cysts at 4 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369252"}
{"pmid": "4369253", "title": "Synaptic regulation of specific protein synthesis in an identified neuron.", "content": "Synaptic regulation of specific protein synthesis in an identified neuron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369253"}
{"pmid": "4369254", "title": "Synergism between polymyxins, polysorbate and antimetabolites of folic acid synthesis, and a paper disc technique for routine testing for synergism.", "content": "Synergism between polymyxins, polysorbate and antimetabolites of folic acid synthesis, and a paper disc technique for routine testing for synergism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369254"}
{"pmid": "4369255", "title": "Synthesis and degradation of the major hepatic phosphofructokinase isozyme in rat liver and hepatoma 3924-A.", "content": "Synthesis and degradation of the major hepatic phosphofructokinase isozyme in rat liver and hepatoma 3924-A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369255"}
{"pmid": "4369256", "title": "Synthesis of (alpha-32P) ribo- and deoxyribonucleoside 5'-triphosphates.", "content": "Synthesis of (alpha-32P) ribo- and deoxyribonucleoside 5'-triphosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369256"}
{"pmid": "4369257", "title": "Synthesis of galactosylphytosphingosine and galactosylceramides containing phytosphingosine.", "content": "Synthesis of galactosylphytosphingosine and galactosylceramides containing phytosphingosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369257"}
{"pmid": "4369258", "title": "Synthesis of substituted piperidino carbamides: correlation between CNS effects and selective inhibition of NAD-dependent oxidations.", "content": "Synthesis of substituted piperidino carbamides: correlation between CNS effects and selective inhibition of NAD-dependent oxidations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369258"}
{"pmid": "4369260", "title": "Systemic chromomycosis in Rana pipiens.", "content": "Systemic chromomycosis in Rana pipiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369260"}
{"pmid": "4369259", "title": "Synthesis of viral-specific RNA in cells infected with the parvovirus, Kilham rat virus.", "content": "Synthesis of viral-specific RNA in cells infected with the parvovirus, Kilham rat virus. We have studied the viral-specific RNA synthesized after infection of a permissive cell line with Kilham rat virus (KRV). The RNA was shown to be virus specific by analysis of its nucleotide base ratios and by hybridization with KRV and cellular DNA. Viral RNA is synthesized as early as 2 h after infection. This viral RNA synthesis occurs before viral progeny DNA synthesis which is initiated at 7 to 8 h after infection. The predominant viral RNA synthesized before and after viral progeny DNA synthesis has a sedimentation coefficient of approximately 18S in dimethylsulfoxide-sucrose gradients and a calculated molecular weight of 6.5 x 10(5) to 7.5 x 10(5). KRV contains a molecule of single-stranded DNA with a molecular weight of approximately 1.6 x 10(6). If the viral-specific 18S RNA is a homogenous species, it would account for 40 to 50% of the viral genome. A small amount of 26S viral RNA with a molecular weight of 1.6 x 10(6) to 1.7 x 10(6) can also be detected. If this 26S RNA is a single viral-specific entity, it could represent a transcription of the entire KRV genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369259"}
{"pmid": "4369262", "title": "Testosterone metabolism and 5 alpha-dihydrotestosterone-binding macromolecule in rat kidney.", "content": "Testosterone metabolism and 5 alpha-dihydrotestosterone-binding macromolecule in rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369262"}
{"pmid": "4369263", "title": "The adenohypophysial response to stress and its hypothalamic control.", "content": "The adenohypophysial response to stress and its hypothalamic control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369263"}
{"pmid": "4369261", "title": "Target cell polarity and membrane phosphorylation in relation to the mechanism of action of antidiuretic hormone.", "content": "Target cell polarity and membrane phosphorylation in relation to the mechanism of action of antidiuretic hormone. The plasma membrane of the bovine renal collecting duct epithelial cell has been resolved into its apical (luminal) and basal-lateral (contraluminal) components by free flow electrophoresis. The contraluminal, but not the luminal, membrane was found to contain antidiuretic hormone-sensitive adenylate cyclase. The luminal membrane was found to contain a cyclic 3':5'-adenosine monophosphate-sensitive self-phosphorylating system consisting of a membrane-bound protein kinase and its membrane-bound substrate(s); this intrinsic protein kinase was not present in the contraluminal membrane. These findings provide direct evidence that the initiating steps in the action of antidiuretic hormone on the kidney take place at the contraluminal pole of the hormonesensitive target cell and that the late or terminal steps occur at the luminal pole, where they involve an alteration in the level of membrane phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369261"}
{"pmid": "4369264", "title": "The advantages of drosophila for mutation studies.", "content": "The advantages of drosophila for mutation studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369264"}
{"pmid": "4369265", "title": "The amino acid sequences of the phosphorylated sites in troponin-I from rabbit skeletal muscle.", "content": "The amino acid sequences of the phosphorylated sites in troponin-I from rabbit skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369265"}
{"pmid": "4369267", "title": "The binding of dexamethasone and triamcinolone acetonide to glucocorticoid receptors in rat skeletal muscle.", "content": "The binding of dexamethasone and triamcinolone acetonide to glucocorticoid receptors in rat skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369267"}
{"pmid": "4369268", "title": "The binding of quinacrine mustard to nucleic acids.", "content": "The binding of quinacrine mustard to nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369268"}
{"pmid": "4369270", "title": "The calcium ionophore A 23 187 as a probe for studying the role of Ca2+ ions in the mediation of carbachol effects on rat salivary glands: protein secretion and metabolism of phospholipids and glycogen.", "content": "The calcium ionophore A 23 187 as a probe for studying the role of Ca2+ ions in the mediation of carbachol effects on rat salivary glands: protein secretion and metabolism of phospholipids and glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369270"}
{"pmid": "4369272", "title": "The cardiodynamic effects and mechanism of action of bretylium tosylate.", "content": "The cardiodynamic effects and mechanism of action of bretylium tosylate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369272"}
{"pmid": "4369273", "title": "The cellular basis of immunosuppression caused by the radiation leukaemia virus.", "content": "The cellular basis of immunosuppression caused by the radiation leukaemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369273"}
{"pmid": "4369271", "title": "The carcinogenic effects of dimethylnitrosamine and nitrosomethylurea in European hamsters (Cricetus cricetus L.).", "content": "The carcinogenic effects of dimethylnitrosamine and nitrosomethylurea in European hamsters (Cricetus cricetus L.). The carcinogenic effects of dimethylnitrosamine (DMN) and nitrosomethylurea (NMU) injected subcutaneously at 3 different dose levels in European hamsters were studied. DMN induced malignant haemangioendotheliomata of the liver and kidney, hepatocellular carcinomata and, in one animal, a cholangiocellular carcinoma. The effect of NMU was localized at the site of administration and resulted in subcutaneous fibrosarcomata, carcinosarcomata or epidermal carcinomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369271"}
{"pmid": "4369266", "title": "The association of congenital malformations and malignant tumors in infants and children.", "content": "The association of congenital malformations and malignant tumors in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369266"}
{"pmid": "4369274", "title": "The chemical basis for the action of the vancomycin group of antibiotics.", "content": "The chemical basis for the action of the vancomycin group of antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369274"}
{"pmid": "4369275", "title": "The continuing evolution of an estrogen-receptor model.", "content": "The continuing evolution of an estrogen-receptor model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369275"}
{"pmid": "4369276", "title": "The control of glycogen synthesis in the liver.", "content": "The control of glycogen synthesis in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369276"}
{"pmid": "4369277", "title": "The control of myelin synthesis and inborn errors of metabolism.", "content": "The control of myelin synthesis and inborn errors of metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369277"}
{"pmid": "4369278", "title": "The covalently bound flavin prosthetic group of beta-cyclopiazonate oxidocyclase.", "content": "The covalently bound flavin prosthetic group of beta-cyclopiazonate oxidocyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369278"}
{"pmid": "4369269", "title": "The biological oxidation of aromatic heterocyclic amines.", "content": "The biological oxidation of aromatic heterocyclic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369269"}
{"pmid": "4369279", "title": "The demonstration of protein synthesis-dependent repair replication in Escherichia coli after treatment with the mono-alkylating agent ethyl methane sulphonate.", "content": "The demonstration of protein synthesis-dependent repair replication in Escherichia coli after treatment with the mono-alkylating agent ethyl methane sulphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369279"}
{"pmid": "4369280", "title": "The development of a new selective medium for the isolation of Brucella abortus from contaminated sources.", "content": "The development of a new selective medium for the isolation of Brucella abortus from contaminated sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369280"}
{"pmid": "4369282", "title": "The diagnostic value of radioimmunoassay in clinical medicine. Discussion.", "content": "The diagnostic value of radioimmunoassay in clinical medicine. Discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369282"}
{"pmid": "4369281", "title": "The diagnosis and management of myasthenia gravis.", "content": "The diagnosis and management of myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369281"}
{"pmid": "4369284", "title": "The dyslipoproteinemias.", "content": "The dyslipoproteinemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369284"}
{"pmid": "4369283", "title": "The distribution of genetic polymorphisms in patients with Down's syndrome.", "content": "The distribution of genetic polymorphisms in patients with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369283"}
{"pmid": "4369286", "title": "The effect of caffeine on the survival of u.v.-irradiated herpes simplex type 1 virus.", "content": "The effect of caffeine on the survival of u.v.-irradiated herpes simplex type 1 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369286"}
{"pmid": "4369285", "title": "The effect of angiotensin-II intravenous infusion on plasma renin activity and prostaglandins A, E, and F levels in the uterine vein of the pregnant monkey.", "content": "The effect of angiotensin-II intravenous infusion on plasma renin activity and prostaglandins A, E, and F levels in the uterine vein of the pregnant monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369285"}
{"pmid": "4369287", "title": "The effect of corticotropin on mouse spleen colony-forming cells.", "content": "The effect of corticotropin on mouse spleen colony-forming cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369287"}
{"pmid": "4369288", "title": "The effect of cAMP on phospholipid metabolism.", "content": "The effect of cAMP on phospholipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369288"}
{"pmid": "4369289", "title": "The effect of disinfectants on bacteriophage phi chi X 174.", "content": "The effect of disinfectants on bacteriophage phi chi X 174.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369289"}
{"pmid": "4369290", "title": "The effect of early undernutrition on the calibre spectrum of the rat optic nerve. Amorphometric ultrastructural study.", "content": "The effect of early undernutrition on the calibre spectrum of the rat optic nerve. Amorphometric ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369290"}
{"pmid": "4369291", "title": "The effect of edema, hydrocortisone acetate, concurrent viral infection and immunization on the clearance of Pasteurella hemolytica from the bovine lung.", "content": "The effect of edema, hydrocortisone acetate, concurrent viral infection and immunization on the clearance of Pasteurella hemolytica from the bovine lung. The influence of pulmonary edema, hydrocortisone, immunization against Pasteurella hemolytica and concurrent infection with parainfluenza-3 virus upon pulmonary clearance of aerosolized P. hemolytica was studied in 31 calves. Following the various treatments calves were challenged with an aerosol of P. hemolytica. One control calf was killed immediately after the aerosol and the numbers of bacteria in the lung taken as 100%. Two calves were killed four hours after challenge and the numbers of bacteria in the lungs were compared to the 100% of the control calf. The result was the percentage clearance of bacteria at four hours. PULMONARY EDEMA WAS INDUCED BY THREE DIFFERENT METHODS: by an aerosol of histamine, by intravenous injection of endotoxin and by intravenous injection of croton oil emulsion. The edema impaired the clearance of P. hemolytica, which was reflected in high numbers of P. hemolytica present in the lungs at four hours after challenge: 260% after histamine, 300% and 400% after endotoxin and 92% after croton oil. SIX DAYS OF TREATMENT OF FOUR CALVES WITH HIGH DOSES OF HYDROCORTISONE ACETATE PRODUCED INCONSISTENT RESULTS: two calves treated with a higher daily dose (36 mg/kg) had normal clearance whereas two calves treated with a lower dose had pulmonary edema and displayed lowered clearance with 111% and 31% respectively of P. hemolytica retained in the lungs four hours after challenge. Immunization of calves by three different methods, a subcutaneously injected bacterin of P. hemolytica (2 calves), single aerosol (2 calves) and four aerosols (4 calves) of live P. hemolytica was reflected in an accelerated pulmonary clearance of P. hemolytica (with a mean of 1.55% of bacteria retained at four hours). Concurrent infection with parainfluenza-3 virus did not lower the clearance of P. hemolytica in the lungs of 12 calves over 15 days except on the first day following the exposure to parainfluenza-3 virus. These calves had hemagglutinating antibodies against P. hemolytica before exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369291"}
{"pmid": "4369292", "title": "The effect of glucagon on the liver cell membrane potential.", "content": "The effect of glucagon on the liver cell membrane potential. 1. Intracellular recordings of membrane potential were made from superficial cells of isolated mouse liver segments superfused with physiological salt solutions.2. The mean resting cell membrane potential was -39.4 mV.3. Glucagon caused a dose-dependent membrane hyperpolarization which was detectable at 10(-9)M and maximal (7 mV) at 10(-7)M. The hyperpolarization started within half a minute after exposure to glucagon. Secretion (2 x 10(-7)M) had no effect on the membrane potential.4. Adrenaline (10(-6)M) and isoprenaline (10(-6)M) also caused membrane hyperpolarization (4-6 mV). The effect of isoprenaline, but not that of adrenaline, was blocked by propranolol (5 x 10(-6)M).5. Dibutyryl adenosine 3',5'-monophosphate (10(-3)M) caused a membrane hyperpolarization of 4-8 mV.6. In the absence of extracellular K or the presence of Strophanthin-G (10(-3)M) the resting potential was decreased and the response to glucagon reduced. During exposure to a solution containing 20 mM-K the resting potential was slightly enhanced and the amplitude of the glucagon-induced hyperpolarization reduced compared with control conditions.7. It is concluded that the effect of glucagon on the membrane potential is due to an interaction with specific membrane receptors probably leading to activation of the membrane-bound adenyl cyclase. It is probable that the hyperpolarization is mediated by cyclic AMP. The hyperpolarization induced by glucagon is dependent on a normal function of the membrane Na-K pump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369292"}
{"pmid": "4369293", "title": "The effect of growth conditions on NAD+ and NADH concentrations and the NAD+:NADH ratio in normal and transformed fibroblasts.", "content": "The effect of growth conditions on NAD+ and NADH concentrations and the NAD+:NADH ratio in normal and transformed fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369293"}
{"pmid": "4369294", "title": "The effect of hepatic injury upon the development of amoebic liver abscess in hamsters.", "content": "The effect of hepatic injury upon the development of amoebic liver abscess in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369294"}
{"pmid": "4369295", "title": "The effect of hydrocortisone and bromodeoxyuridine (BUdR) on the Epstein-Barr herpes virus in human lymphoblastoid cell lines.", "content": "The effect of hydrocortisone and bromodeoxyuridine (BUdR) on the Epstein-Barr herpes virus in human lymphoblastoid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369295"}
{"pmid": "4369296", "title": "The effect of intravenously administered prostaglandin E2 on rat uterine 3',5'-adenosine monophosphate.", "content": "The effect of intravenously administered prostaglandin E2 on rat uterine 3',5'-adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369296"}
{"pmid": "4369297", "title": "The effect of noradrenaline and tyramine on cardiac contractility, cyclic AMP, and phosphorylase a in normal and hyperthyroid rats.", "content": "The effect of noradrenaline and tyramine on cardiac contractility, cyclic AMP, and phosphorylase a in normal and hyperthyroid rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369297"}
{"pmid": "4369298", "title": "The effect of polychlorinated biphenyls on liver gluconeogenic enzyme activities in rats during exposure to cold.", "content": "The effect of polychlorinated biphenyls on liver gluconeogenic enzyme activities in rats during exposure to cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369298"}
{"pmid": "4369299", "title": "The effect of tyrosinase on glyceraldehyde-3-phosphate dehydrogenase and glycerophosphate dehydrogenase.", "content": "The effect of tyrosinase on glyceraldehyde-3-phosphate dehydrogenase and glycerophosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369299"}
{"pmid": "4369301", "title": "The effects of epinephrine, prostaglandins, and their antagonists on adenosine cyclic 3',5'-monophosphate concentrations and motility of the rat uterus.", "content": "The effects of epinephrine, prostaglandins, and their antagonists on adenosine cyclic 3',5'-monophosphate concentrations and motility of the rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369301"}
{"pmid": "4369302", "title": "The effects of eye movement and dark-adaptation on transmission through the visual pathways of unrestrained cats.", "content": "The effects of eye movement and dark-adaptation on transmission through the visual pathways of unrestrained cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369302"}
{"pmid": "4369303", "title": "The effects of hyperosmolarity on the blood-brain barrier. A morphological and physiological correlation.", "content": "The effects of hyperosmolarity on the blood-brain barrier. A morphological and physiological correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369303"}
{"pmid": "4369305", "title": "The effects of parental composition on recidivism rates in delinquent girls.", "content": "The effects of parental composition on recidivism rates in delinquent girls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369305"}
{"pmid": "4369304", "title": "The effects of infusions of synthetic adrenocorticotrophin in the conscious calf.", "content": "The effects of infusions of synthetic adrenocorticotrophin in the conscious calf. 1. A technique is described by which the whole of the effluent blood from the right adrenal gland can be collected as required from conscious, unrestrained calves. The technique may be used to measure adrenal blood flow gravimetrically and to compute the output of adrenal hormones under various conditions in the normal calf.2. In a group of seven calves mean cortisol output from the right adrenal gland was found to vary between 20 and 40 ng.kg(-1) min(-1) and corticosterone between 6 and 18 ng.kg(-1) min(-1) during a 2 hr period, 24 hr after surgery.3. Intravenous infusions of synthetic adrenocorticotrophin (5 ng.kg(-1) min(-1)) produced a significant increase in the output of both cortisol and corticosterone within 5 min. The output of both hormones rose to maximal values within 10-20 min and mean values of approximately 300 ng.kg(-1) min(-1) (cortisol) and 120 ng.kg(-1) min(-1) (corticosterone) were maintained thereafter for the duration of the infusion (120 min). The output of both steroids fell to values comparable with those observed initially within 45-60 min after the infusion was discontinued.4. These changes in glucocorticoid output in response to adrenocorticotrophin produced a significant rise in the concentration of both cortisol and corticosterone in peripheral plasma. It is noteworthy that the rise in the mean corticosterone concentration in the peripheral plasma was substantially less than that which might be expected from relating the rise in mean plasma cortisol concentration to cortisol output.5. The results of control experiments have eliminated the possibility that the sampling procedure might itself increase steroid output or peripheral plasma concentration. Comparison of results from calves of widely disparate ages (8-38 days) provided no evidence that either the resting output of cortisol or corticosterone or the response to adrenocorticotrophin changes with age within the range examined.6. Infusion of adrenocorticotrophin (5 ng.kg(-1) min(-1)) also stimulated an abrupt rise in adrenal blood flow; mean resting flow (210 +/- 23 mul.kg(-1)) increased by approximately 30% within 5 min and attained peak values (355-365 mul.kg(-1) min(-1)) between 10 and 30 min. Thereafter, adrenal blood flow steadily decreased and then fell rapidly to within the resting range when the infusion was terminated. No significant changes in heart rate or aortic blood pressure occurred during these infusions.7. The results are discussed in relation to those obtained in other species and under differing conditions by other workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369304"}
{"pmid": "4369300", "title": "The effect of REM deprivation on depression.", "content": "The effect of REM deprivation on depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369300"}
{"pmid": "4369306", "title": "The effects of thallium salts, with particular reference to the nervous system changes. A report of three cases.", "content": "The effects of thallium salts, with particular reference to the nervous system changes. A report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369306"}
{"pmid": "4369308", "title": "The epithelium of the urinary bladder of rock hyrax.", "content": "The epithelium of the urinary bladder of rock hyrax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369308"}
{"pmid": "4369307", "title": "The effects of theophylline on cyclic adenosine monophosphate metabolism in lymphocytes from open-angle glaucoma patients.", "content": "The effects of theophylline on cyclic adenosine monophosphate metabolism in lymphocytes from open-angle glaucoma patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369307"}
{"pmid": "4369309", "title": "The human plasma kallikrein-kinin system.", "content": "The human plasma kallikrein-kinin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369309"}
{"pmid": "4369310", "title": "The identification of intermediates in the reaction of pig heart lactate dehydrogenase with its substrates.", "content": "The identification of intermediates in the reaction of pig heart lactate dehydrogenase with its substrates. Pig heart lactate dehydrogenase was studied in the direction of pyruvate and NADH formation by recording rapid changes in extinction, proton concentration, nucleotide fluorescence and protein fluorescence. Experiments measuring extinction changes show that there is a very rapid formation of NADH within the first millisecond and that the amplitude of this phase (phase 1) increases threefold over the pH range 6-8. A second transient rate (phase 2) can also be distinguished (whose rate is pH-dependent), followed by a steady-state rate (phase 3) of NADH production. The sum of the amplitudes of the first two phases corresponds to 1mol of NADH produced/mol of active sites of lactate dehydrogenase. Experiments that measured the liberation of protons by using Phenol Red as an indicator show that no proton release occurs during the initial very rapid formation of NADH (phase 1), but protons are released during subsequent phases of NADH production. Fluorescence experiments help to characterize these phases, and show that the very rapid phase 1 corresponds to the establishment of an equilibrium between E(NAD) (Lactate) right harpoon over left harpoon H(+)E(NADH) (Pyruvate). This equilibrium can be altered by changing lactate concentration or pH, and the H(+)E(NADH) (Pyruvate) species formed has very low nucleotide fluorescence and quenched protein fluorescence. Phase 2 corresponds to the dissociation of pyruvate and a proton from the complex with a rate constant of 1150s(-1). The observed rate constant is slower than this and is proportional to the position of the preceding equilibrium. The E(NADH) formed has high nucleotide fluorescence and quenched protein fluorescence. The reaction, which is rate-limiting during steady-state turnover, must then follow this step and be involved with dissociation of NADH from the enzyme or some conformational change immediately preceding dissociation. Several inhibitory complexes have also been studied including E(NAD+) (Oxamate) and E(NADH) (Oxamate') and the abortive ternary complex E(NADH) (Lactate). The rate of NADH dissociation from the enzyme was measured and found to be the same whether measured by ligand displacement or by relaxation experiments. These results are discussed in relation to the overall mechanism of lactate dehydrogenase turnover and the independence of the four binding sites in the active tetramer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369310"}
{"pmid": "4369311", "title": "The identification of phosphatidylglycerol in the rat, rabbit, monkey and human lung.", "content": "The identification of phosphatidylglycerol in the rat, rabbit, monkey and human lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369311"}
{"pmid": "4369313", "title": "The immunological system and the development of central nervous system lesions in acute viral infections.", "content": "The immunological system and the development of central nervous system lesions in acute viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369313"}
{"pmid": "4369312", "title": "The immunological basis of glomerulonephritis.", "content": "The immunological basis of glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369312"}
{"pmid": "4369315", "title": "The incidence of cytomegalovirus among mentally retarded and microcephalic children in a state institution.", "content": "The incidence of cytomegalovirus among mentally retarded and microcephalic children in a state institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369315"}
{"pmid": "4369316", "title": "The information content of protein amino acid sequences.", "content": "The information content of protein amino acid sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369316"}
{"pmid": "4369314", "title": "The in vivo effects of leucine dehydrogenase from Bacillus sphaericus.", "content": "The in vivo effects of leucine dehydrogenase from Bacillus sphaericus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369314"}
{"pmid": "4369317", "title": "The inhibition of brain choline kinase by hemicholinium-3.", "content": "The inhibition of brain choline kinase by hemicholinium-3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369317"}
{"pmid": "4369318", "title": "The inhibition of ribonuclease activity and the isolation of polysomes from leaves of the french bean, Phaseolus vulgaris.", "content": "The inhibition of ribonuclease activity and the isolation of polysomes from leaves of the french bean, Phaseolus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369318"}
{"pmid": "4369319", "title": "The intake, digestion and utilization of food and growth rate of lambs affected by Trichostrongylus colubriformis.", "content": "The intake, digestion and utilization of food and growth rate of lambs affected by Trichostrongylus colubriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369319"}
{"pmid": "4369320", "title": "The interaction of apolipoprotein-serine with phosphatidylcholine.", "content": "The interaction of apolipoprotein-serine with phosphatidylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369320"}
{"pmid": "4369321", "title": "The interaction of uterine estrogen receptors with DNA.", "content": "The interaction of uterine estrogen receptors with DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369321"}
{"pmid": "4369322", "title": "The interaction of vasoactive intestinal polypeptide and secretin with liver-cell membranes.", "content": "The interaction of vasoactive intestinal polypeptide and secretin with liver-cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369322"}
{"pmid": "4369323", "title": "The lipids of the alga Spirulina.", "content": "The lipids of the alga Spirulina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369323"}
{"pmid": "4369325", "title": "The mechanism of reaction of Cys- 149 of D-glyceraldehyde-3-phosphate dehydrogenase with p-hydroxy-mercuribenzoate.", "content": "The mechanism of reaction of Cys- 149 of D-glyceraldehyde-3-phosphate dehydrogenase with p-hydroxy-mercuribenzoate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369325"}
{"pmid": "4369326", "title": "The metabolic response to exercise and exhaustion in normal and growth-hormone-deficient children.", "content": "The metabolic response to exercise and exhaustion in normal and growth-hormone-deficient children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369326"}
{"pmid": "4369327", "title": "The motor neuron surface and spinal shock.", "content": "The motor neuron surface and spinal shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369327"}
{"pmid": "4369324", "title": "The lysosomal enzymes in lymphocytes. II. Activated lymphocytes.", "content": "The lysosomal enzymes in lymphocytes. II. Activated lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369324"}
{"pmid": "4369328", "title": "The motor unit profile of the rat soleus in experimental myopathy and reinnervation.", "content": "The motor unit profile of the rat soleus in experimental myopathy and reinnervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369328"}
{"pmid": "4369329", "title": "The nature and distribution of enzymes catalyzing the conjugation of glutathione with foreign compounds.", "content": "The nature and distribution of enzymes catalyzing the conjugation of glutathione with foreign compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369329"}
{"pmid": "4369330", "title": "The normal short child. Community study of children in Newcastle upon Tyne.", "content": "The normal short child. Community study of children in Newcastle upon Tyne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369330"}
{"pmid": "4369331", "title": "The nucleotide sequence of the cytoplasmic initiator transfer RNA of a mouse myeloma cell.", "content": "The nucleotide sequence of the cytoplasmic initiator transfer RNA of a mouse myeloma cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369331"}
{"pmid": "4369332", "title": "The occurrence of intermediates in mitochondrial fatty acid oxidation.", "content": "The occurrence of intermediates in mitochondrial fatty acid oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369332"}
{"pmid": "4369333", "title": "The organization of extraocular muscles in Anura.", "content": "The organization of extraocular muscles in Anura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369333"}
{"pmid": "4369334", "title": "The pancreatic beta-cell recognition of insulin secretogogues. Influence of neuraminidase treatment on the release of insulin and the islet content of insulin, sialic acid, and cyclic adenosine 3':5'-monophosphate.", "content": "The pancreatic beta-cell recognition of insulin secretogogues. Influence of neuraminidase treatment on the release of insulin and the islet content of insulin, sialic acid, and cyclic adenosine 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369334"}
{"pmid": "4369338", "title": "The poly(adenylic acid) sequence of mouse globin messenger RNA.", "content": "The poly(adenylic acid) sequence of mouse globin messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369338"}
{"pmid": "4369336", "title": "The peripheral lung pulse in pulmonary carcinoma. A cinedensigraphic study based on 174 proven cases.", "content": "The peripheral lung pulse in pulmonary carcinoma. A cinedensigraphic study based on 174 proven cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369336"}
{"pmid": "4369335", "title": "The pathology of 3-Nitro-4-hydroxyphanylarsonic acid toxicity in turkeys.", "content": "The pathology of 3-Nitro-4-hydroxyphanylarsonic acid toxicity in turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369335"}
{"pmid": "4369337", "title": "The phosphorylation sites of troponin I from white skeletal muscle of the rabbit.", "content": "The phosphorylation sites of troponin I from white skeletal muscle of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369337"}
{"pmid": "4369339", "title": "The preparation and properties of pyruvate kinase from yeast.", "content": "The preparation and properties of pyruvate kinase from yeast. A new method is described for the preparation of pyruvate kinase from yeast. This eliminates proteolysis during the preparation. The molecular weight of yeast pyruvate kinase is 215000, and it is composed of four subunits. Such properties of the enzyme as its extinction coefficient, cold-lability, thiol-group reactivity and binding of Mn(2+) ions are compared with those previously reported for yeast pyruvate kinase prepared by different methods. The specific activity is significantly higher than previously observed, but otherwise the enzyme is similar, apart from its molecular weight and Mn(2+)-binding characteristics, to preparations from Saccharomyces cerevisiae obtained in this laboratory (e.g. Fell et al., 1972, and references therein) and that of C. H. Suelter (e.g. Kuczenski & Suelter, 1971, and references therein), and is different from the enzyme isolated from Saccharomyces carlsbergensis by B. Hess and his co-workers (e.g. Wieker & Hess, 1972, and references therein).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369339"}
{"pmid": "4369340", "title": "The primary structure of apolopoprotein-serine.", "content": "The primary structure of apolopoprotein-serine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369340"}
{"pmid": "4369341", "title": "The production of limit-oligonucleotide digests from phenylalanine tRNA (Escherichia coli) with snake venom phosphodiesterase.", "content": "The production of limit-oligonucleotide digests from phenylalanine tRNA (Escherichia coli) with snake venom phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369341"}
{"pmid": "4369344", "title": "The purification of cell nuclei from calf uterus by zonal centrifugation in reorienting density gradients.", "content": "The purification of cell nuclei from calf uterus by zonal centrifugation in reorienting density gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369344"}
{"pmid": "4369342", "title": "The production of superoxide radical during the decomposition of potassium peroxochromate(V).", "content": "The production of superoxide radical during the decomposition of potassium peroxochromate(V).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369342"}
{"pmid": "4369343", "title": "The psychogeriatric patient in hospital.", "content": "The psychogeriatric patient in hospital. The records of 148 geriatric patients discharged from the Royal Ottawa Hospital over an 18-month period were studied. The readmission rate, 38%, was similar to that of all inpatients in this hospital. The largest diagnostic category was depressive neurosis. More women than men had diagnoses of affective disorders, while more men had organic brain disease; these differences were statistically significant. The average length of hospital stay was 25 days. Those patients with diagnoses of organic brain disease and alcoholism had shorter stays than those with affective disorders. The implications of these findings in terms of setting up a psychogeriatric unit are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369343"}
{"pmid": "4369345", "title": "The pH-dependence of ESR spectra from nitroxide probes in lecithin dispersions.", "content": "The pH-dependence of ESR spectra from nitroxide probes in lecithin dispersions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369345"}
{"pmid": "4369346", "title": "The rate of cholesterol 'flip-flop' in lipid bilayers and its relation to membrane sterol pools.", "content": "The rate of cholesterol 'flip-flop' in lipid bilayers and its relation to membrane sterol pools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369346"}
{"pmid": "4369347", "title": "The rate-limiting step of adrenal steroidogenesis and adenosine 3':5'-monophosphate.", "content": "The rate-limiting step of adrenal steroidogenesis and adenosine 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369347"}
{"pmid": "4369348", "title": "The regulation of calciferol-25-hydroxylase in the chick.", "content": "The regulation of calciferol-25-hydroxylase in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369348"}
{"pmid": "4369349", "title": "The regulatory center of D-glyceraldehyde-3-phosphate dehydrogenase.", "content": "The regulatory center of D-glyceraldehyde-3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369349"}
{"pmid": "4369350", "title": "The renin-angiotensin system in acute renal failure in rats.", "content": "The renin-angiotensin system in acute renal failure in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369350"}
{"pmid": "4369351", "title": "The renin-angiotensin system of uninephrectomized rats under diuretic treatment.", "content": "The renin-angiotensin system of uninephrectomized rats under diuretic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369351"}
{"pmid": "4369352", "title": "The respiratory system of the marine bacterium Beneckea natriegens. Oxidation--reduction potentials of the cytochromes.", "content": "The respiratory system of the marine bacterium Beneckea natriegens. Oxidation--reduction potentials of the cytochromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369352"}
{"pmid": "4369353", "title": "The role of cyclic AMP in the modulation of cardiac contractility.", "content": "The role of cyclic AMP in the modulation of cardiac contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369353"}
{"pmid": "4369355", "title": "The role of prolactin in the depressed or 'buffered' adrenocorticosteroid response of the rat.", "content": "The role of prolactin in the depressed or 'buffered' adrenocorticosteroid response of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369355"}
{"pmid": "4369354", "title": "The role of cyclic AMP in the regulation of steroid biosynthesis in testis tissue.", "content": "The role of cyclic AMP in the regulation of steroid biosynthesis in testis tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369354"}
{"pmid": "4369356", "title": "The role of sialic acid in determining the survival of transcortin in the circulation.", "content": "The role of sialic acid in determining the survival of transcortin in the circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369356"}
{"pmid": "4369357", "title": "The sensitivity of function tests in detecting liver damage in the rat.", "content": "The sensitivity of function tests in detecting liver damage in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369357"}
{"pmid": "4369359", "title": "The specificity of dimethylbenzylrifampicin as an inhibitor of viral induced transformation.", "content": "The specificity of dimethylbenzylrifampicin as an inhibitor of viral induced transformation. The effect of 2',6'-dimethyl-N(4')-benzyl-N(4')- [desmethyl]rifampicin on viral transformation induced by two unrelated oncogenic viruses was compared. Transformation of Balb/3T3 cells by the small, DNA-containing papova virus simian virus 40 was completely normal under conditions where transformation by the large, RNA-containing oncornavirus murine sarcoma virus was inhibited more than 150-fold. For these experiments a resistant variant of Balb/3T3 was selected that grows well in high concentrations of the drug, is not dependent on the drug for growth, and is probably not blocked at the level of drug uptake. These data show that dimethyl-benzylrifampicin specifically inhibits oncornavirus-induced transformation rather than nonspecifically inhibiting cellular growth or transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369359"}
{"pmid": "4369358", "title": "The sodium-potassium adenosinetriphosphatase.", "content": "The sodium-potassium adenosinetriphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369358"}
{"pmid": "4369360", "title": "The stability of PGM and AK isoenzymes in human tissues.", "content": "The stability of PGM and AK isoenzymes in human tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369360"}
{"pmid": "4369361", "title": "The stoichiometry of the three different types of copper in ascorbate oxidase from green zucchini squash.", "content": "The stoichiometry of the three different types of copper in ascorbate oxidase from green zucchini squash.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369361"}
{"pmid": "4369362", "title": "The structure of cytochrome oxidase membranes.", "content": "The structure of cytochrome oxidase membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369362"}
{"pmid": "4369363", "title": "The structure of the posterior piriform cortex in the dog.", "content": "The structure of the posterior piriform cortex in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369363"}
{"pmid": "4369365", "title": "The surface structure of polyoma virus.", "content": "The surface structure of polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369365"}
{"pmid": "4369364", "title": "The subfractionation of platelet membranes by zonal centrifugation: identification of surface membranes.", "content": "The subfractionation of platelet membranes by zonal centrifugation: identification of surface membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369364"}
{"pmid": "4369366", "title": "The synthesis of encephalomyocarditis virus polypeptides in infected L-cells and cell-free systems.", "content": "The synthesis of encephalomyocarditis virus polypeptides in infected L-cells and cell-free systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369366"}
{"pmid": "4369369", "title": "The treatment of muscular subaortic stenosis.", "content": "The treatment of muscular subaortic stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369369"}
{"pmid": "4369370", "title": "The ultrastructure of cartilage cells in the epiphyses of long bones in the domestic fowl.", "content": "The ultrastructure of cartilage cells in the epiphyses of long bones in the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369370"}
{"pmid": "4369367", "title": "The temperature-dependent enzymatic breakdown of ribosomal RNA of reticulocytes. The nucleoside plus mononucleotide fraction.", "content": "The temperature-dependent enzymatic breakdown of ribosomal RNA of reticulocytes. The nucleoside plus mononucleotide fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369367"}
{"pmid": "4369371", "title": "The ultrastructure of Dentalium egg at the trefoil stage.", "content": "The ultrastructure of Dentalium egg at the trefoil stage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369371"}
{"pmid": "4369373", "title": "The use of red light for handling wild rats.", "content": "The use of red light for handling wild rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369373"}
{"pmid": "4369372", "title": "The use of deoxyfluoro-D-galactopyranoses in a study of yeast galactokinase specificity.", "content": "The use of deoxyfluoro-D-galactopyranoses in a study of yeast galactokinase specificity. 1. 2-Deoxy-2-fluoro-d-galactose, 3-deoxy-3-fluoro-d-galactose, 4-deoxy-4-fluoro-d-galactose, 6-deoxy-6-fluoro-d-galactose and 2-deoxy-d-lyxo-hexose are substrates for yeast galactokinase. 2. The variation in K(m) values for the d-hexose derivatives was not associated with a variation in the value of K(m) for MgATP(2-) indicating that the binding of MgATP(2-) is not modified by the binding of the sugar substrate. 3. Donated H bonds from OH-3, OH-4 and OH-6 and an accepted H bond to OH-2 of the d-hexose are important for the binding of the sugar substrate to galactokinase. 4. Yeast galactokinase exhibits similar kinetics to the galactokinase from Escherichia coli and operates by a similar random sequential mechanism. 5. 4-Deoxy-4-fluoro-d-glucose was neither a substrate for nor an inhibitor of yeast galactokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369372"}
{"pmid": "4369368", "title": "The theme is change.", "content": "The theme is change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369368"}
{"pmid": "4369375", "title": "The RNA of defective vesicular stomatitis virus particles in relation to viral cistrons.", "content": "The RNA of defective vesicular stomatitis virus particles in relation to viral cistrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369375"}
{"pmid": "4369376", "title": "The SV40-induced T-antigen in mouse cells.", "content": "The SV40-induced T-antigen in mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369376"}
{"pmid": "4369378", "title": "Theory of radioimmunoassays and hormone-receptor interactions. II. Simulation of antibody divalency, cooperativity and allosteric effects.", "content": "Theory of radioimmunoassays and hormone-receptor interactions. II. Simulation of antibody divalency, cooperativity and allosteric effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369378"}
{"pmid": "4369379", "title": "Thermography of the eye during cold stress.", "content": "Thermography of the eye during cold stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369379"}
{"pmid": "4369374", "title": "The use of ribosubstitution techniques for determining DNA sequences.", "content": "The use of ribosubstitution techniques for determining DNA sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369374"}
{"pmid": "4369377", "title": "Theory of hormone-receptor interaction. 3. The endocrine target cell as a quantal response unit: a general control mechanism.", "content": "Theory of hormone-receptor interaction. 3. The endocrine target cell as a quantal response unit: a general control mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369377"}
{"pmid": "4369380", "title": "Thymic lymphocytes in obese (ob-ob) mice. A mirror of the insulin receptor defect in liver and fat.", "content": "Thymic lymphocytes in obese (ob-ob) mice. A mirror of the insulin receptor defect in liver and fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369380"}
{"pmid": "4369381", "title": "Thymus graft in four children: clinical and immunological results.", "content": "Thymus graft in four children: clinical and immunological results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369381"}
{"pmid": "4369383", "title": "Thyroid lymphography.", "content": "Thyroid lymphography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369383"}
{"pmid": "4369384", "title": "Tissue differences in the concentration of triiodothyronine nuclear binding sites in the rat: liver, kidney, pituitary, heart, brain, spleen, and testis.", "content": "Tissue differences in the concentration of triiodothyronine nuclear binding sites in the rat: liver, kidney, pituitary, heart, brain, spleen, and testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369384"}
{"pmid": "4369382", "title": "Thyroid function following partial thyroidectomy.", "content": "Thyroid function following partial thyroidectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369382"}
{"pmid": "4369385", "title": "Toxic effects of anticonvulsants: general principles.", "content": "Toxic effects of anticonvulsants: general principles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369385"}
{"pmid": "4369387", "title": "Toxic properties of chlorine trifluoride.", "content": "Toxic properties of chlorine trifluoride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369387"}
{"pmid": "4369389", "title": "Toxicity studies on tetrasul. 3. Short-term comparative studies in rats with tetrasul and structurally related acaricides.", "content": "Toxicity studies on tetrasul. 3. Short-term comparative studies in rats with tetrasul and structurally related acaricides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369389"}
{"pmid": "4369388", "title": "Toxicity studies on tertrasul. II. Short-term comparative studies in 6 animal species.", "content": "Toxicity studies on tertrasul. II. Short-term comparative studies in 6 animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369388"}
{"pmid": "4369386", "title": "Toxic polyneuropathy due to glue sniffing.", "content": "Toxic polyneuropathy due to glue sniffing. Four cases of toxic polyneuropathy due to glue-sniffing were reported. Neurological examination revealed motor predominant mixed type polyneuropathy. The cause of polyneuropathies in these cases was considered to be due to the inhalation of the vaporized elements of the adhesive agent, which contain mainly n-hexane and toluene. N-hexane is considered to be chiefly responsible for the polyneuropathy, though toluene also could have some influence on the illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369386"}
{"pmid": "4369390", "title": "Transcortin: a corticosteroid-binding protein of plasma. XII. Immunologic studies on transcortin in guinea-pig tissues.", "content": "Transcortin: a corticosteroid-binding protein of plasma. XII. Immunologic studies on transcortin in guinea-pig tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369390"}
{"pmid": "4369392", "title": "Transfection of chicken embryo cells with DNA extracted from avian virus-producing neoplastic cells.", "content": "Transfection of chicken embryo cells with DNA extracted from avian virus-producing neoplastic cells. DNA isolated from avian virus-producing leukemic myeloblasts induced the production of viruses, but not morphological transformation, in cultivated chicken fibroblasts. The recovered virus had the same biological characteristics as the original avian myeloblastosis virus (AMV) and produced myeloblastosis and nephroblastomas when injected into chickens. Neutralization experiments with chicken anti-AMV-BAI strain A sera showed an antigenic community between the DNA-transfected virus and the original virus. Virus induced in fibroblasts after treatment with DNA from a viral nephroblastic nephroblastoma line only gave nephroblastoma when injected into chicken. Treatment of chicken embryo cells with DNA extracted from normal chicken embryos did not induce viral production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369392"}
{"pmid": "4369391", "title": "Transcribing complexes in cells infected by vesicular stomatitis virus and rabies virus.", "content": "Transcribing complexes in cells infected by vesicular stomatitis virus and rabies virus. We analyzed cell extracts from BHK(21) cells infected with vesicular stomatitis virus (VSV) and rabies virus for in vitro RNA polymerase activity. Cells infected with VSV B virions exhibited several complexes with in vitro RNA polymerase activity in sucrose gradients. These complexes synthesize VSV transcriptase product (4 to 18S) polyadenylated in RNA complementary to virion RNA. Cells infected with a high multiplicity of B virions and T particles show only one RNA polymerase complex active in vitro. This complex sediments at 110S and makes only small (2S) RNA. Carrier BHK(21) cells persistently noncytopathically infected with VSV contain several complexes active in RNA polymerase, but both exhibit very low activity. Cytoplasms of cells noncytopathically infected with rabies virus also show very low levels of a complex containing RNA polymerase activity. No transcriptase nor any other in vitro polymerase activity could be found associated with purified rabies virions, although they do carry out primary transcription in cells treated with actinomycin D and cycloheximide before infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369391"}
{"pmid": "4369393", "title": "Transfer of very low density lipoprotein from hen plasma into egg yolk.", "content": "Transfer of very low density lipoprotein from hen plasma into egg yolk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369393"}
{"pmid": "4369394", "title": "Transient monoclonal gammopathy associated with cytomegalovirus infection.", "content": "Transient monoclonal gammopathy associated with cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369394"}
{"pmid": "4369396", "title": "Treatment of a case of sympathetic ophthalmia.", "content": "Treatment of a case of sympathetic ophthalmia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369396"}
{"pmid": "4369395", "title": "Translation of reovirus mRNA, poliovirus RNA and bacteriophage Qbeta RNA in cell-free extracts of mammalian cells.", "content": "Translation of reovirus mRNA, poliovirus RNA and bacteriophage Qbeta RNA in cell-free extracts of mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369395"}
{"pmid": "4369398", "title": "Treatment of retinoblastoma.", "content": "Treatment of retinoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369398"}
{"pmid": "4369397", "title": "Treatment of hyperlipoproteinaemia type II A with a new anion exchange resin secholex.", "content": "Treatment of hyperlipoproteinaemia type II A with a new anion exchange resin secholex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369397"}
{"pmid": "4369399", "title": "Treatment of stabilized liver cirrhosis by dehydroepiandrosterone sulphate. I. Evaluation of principal biochemical tests as a whole.", "content": "Treatment of stabilized liver cirrhosis by dehydroepiandrosterone sulphate. I. Evaluation of principal biochemical tests as a whole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369399"}
{"pmid": "4369400", "title": "Trehalose metabolism by Bacillus popilliae.", "content": "Trehalose metabolism by Bacillus popilliae. Trehalose was found to be utilized more readily than glucose for the growth of Bacillus popilliae NRRL B-2309MC. The pathway of degradation of trehalose was elucidated and found to differ from that reported for other organisms. Trehalase and trehalose phosphorylase activities could not be detected. Rather, trehalose was found to undergo phosphoenolpyruvate (PEP)-dependent phosphorylation, and the resulting trehalose 6-phosphate was cleaved by a phosphotrehalase to equimolar amounts of glucose and glucose 6-phosphate. The phosphotrehalase was purified 34-fold and shown to have a pH optimum of 6.5 to 7.0 and a K(m) for trehalose 6-phosphate of 1.8 mM. A mutant missing the phosphotrehalase failed to grow on trehalose but grew normally on other sugars. The mutant accumulated [(14)C]trehalose as [(14)C]trehalose 6-phosphate. Phosphorylation of trehalose by dialyzed extracts was at least 25 times faster with PEP than with adenosine 5'-triphosphate, and the phosphorylation activity was associated primarily with the particulate fraction. These data and the results of studies of [(14)C]trehalose uptake suggest that trehalose is transported into the cell as trehalose 6-phosphate by a PEP:sugar phosphotransferase system. Cell extracts of other strains of B. popilliae were also found to produce [(14)C]sugar phosphate from [(14)C]trehalose and to have phosphotrehalase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369400"}
{"pmid": "4369401", "title": "Trisomy-9 in the bone marrow of a patient with acute myelomonoblastic leukaemia.", "content": "Trisomy-9 in the bone marrow of a patient with acute myelomonoblastic leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369401"}
{"pmid": "4369402", "title": "Tritium sequence analysis of polyribonucleotides following periodate-phosphomonoesterase degradation--analysis of nucleoside methylene dialdehydes derived from tetra-, penta-, and hexanucleotides.", "content": "Tritium sequence analysis of polyribonucleotides following periodate-phosphomonoesterase degradation--analysis of nucleoside methylene dialdehydes derived from tetra-, penta-, and hexanucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369402"}
{"pmid": "4369403", "title": "Tumor-specific membrane antigens in established cell lines from gliomas.", "content": "Tumor-specific membrane antigens in established cell lines from gliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369403"}
{"pmid": "4369404", "title": "Tumors in Gerbillinae: a literature review and report of a case.", "content": "Tumors in Gerbillinae: a literature review and report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369404"}
{"pmid": "4369405", "title": "Type 2 hyperprolinemia: absence of delta1-pyrroline-5-carboxylic acid dehydrogenase activity.", "content": "Type 2 hyperprolinemia: absence of delta1-pyrroline-5-carboxylic acid dehydrogenase activity. triangle up(1)-Pyrroline-5-carboxylic acid dehydrogenase activity was measured radioisotopically in normal and type 2 hyperprolinemia fibroblasts. The type 2 cells had no detectable activity over a range of reaction conditions whereas normal cells had easily measurable activity. This enzymatic defect accounts for the biochemical abnormalities in type 2 hyperprolinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369405"}
{"pmid": "4369406", "title": "TSH initiation of hormone secretion by rat thyroid lobes in vitro.", "content": "TSH initiation of hormone secretion by rat thyroid lobes in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369406"}
{"pmid": "4369407", "title": "Ultrasonic diagnosis in melanoma and retinoblastoma.", "content": "Ultrasonic diagnosis in melanoma and retinoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369407"}
{"pmid": "4369409", "title": "Ultrastructural changes produced in Proteus vulgaris by a synergistic combination of colistin and sulphadiazine.", "content": "Ultrastructural changes produced in Proteus vulgaris by a synergistic combination of colistin and sulphadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369409"}
{"pmid": "4369410", "title": "Ultrastructural examination of various stages of amelogenesis in the rat following parenteral fluoride administration.", "content": "Ultrastructural examination of various stages of amelogenesis in the rat following parenteral fluoride administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369410"}
{"pmid": "4369408", "title": "Ultrastructural alterations of rat brain microglial cells and pericytes after chronic lead poisoning.", "content": "Ultrastructural alterations of rat brain microglial cells and pericytes after chronic lead poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369408"}
{"pmid": "4369411", "title": "Ultrastructural observations of anterior pituitary somatotrophs following pituitary portal vessel infusion of dibutyryl cAMP.", "content": "Ultrastructural observations of anterior pituitary somatotrophs following pituitary portal vessel infusion of dibutyryl cAMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369411"}
{"pmid": "4369412", "title": "Ultrastructural studies on tumours and cell cultures of the Harding--Passey mouse melanoma.", "content": "Ultrastructural studies on tumours and cell cultures of the Harding--Passey mouse melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369412"}
{"pmid": "4369414", "title": "Ultrastructural study of brain lesions produced in mice by the administration of Clostridium welchii type D toxin.", "content": "Ultrastructural study of brain lesions produced in mice by the administration of Clostridium welchii type D toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369414"}
{"pmid": "4369413", "title": "Ultrastructural study of androgen-producing adrenocortical adenoma.", "content": "Ultrastructural study of androgen-producing adrenocortical adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369413"}
{"pmid": "4369415", "title": "Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. II. Vegetative yeast form grown under anaerobic conditions.", "content": "Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. II. Vegetative yeast form grown under anaerobic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369415"}
{"pmid": "4369418", "title": "Ultrastructure of the chamber angle after a short period of high intraocular pressure.", "content": "Ultrastructure of the chamber angle after a short period of high intraocular pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369418"}
{"pmid": "4369416", "title": "Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. 3. Dormant sporangiospore.", "content": "Ultrastructure of polymorphic Mucor as observed by means of freeze-etching. 3. Dormant sporangiospore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369416"}
{"pmid": "4369419", "title": "Ultrastructure of the extended ribonucleic acid molecules from purified ribosomes of Rous sarcoma virus-induced mouse ascites sarcoma cells.", "content": "Ultrastructure of the extended ribonucleic acid molecules from purified ribosomes of Rous sarcoma virus-induced mouse ascites sarcoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369419"}
{"pmid": "4369420", "title": "Ultraviolet-enhanced reactivation of Herpes virus in human tumor cells.", "content": "Ultraviolet-enhanced reactivation of Herpes virus in human tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369420"}
{"pmid": "4369421", "title": "Untreated neonatal herpes simplex 2 meningitis without apparent neurologic damage.", "content": "Untreated neonatal herpes simplex 2 meningitis without apparent neurologic damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369421"}
{"pmid": "4369417", "title": "Ultrastructure of pure cultures of Physarum flavicomum. 1. Conversion of a plasmodium to microplasmodia and microsclerotia, and the process of slime secretion.", "content": "Ultrastructure of pure cultures of Physarum flavicomum. 1. Conversion of a plasmodium to microplasmodia and microsclerotia, and the process of slime secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369417"}
{"pmid": "4369423", "title": "Urinary excretion and cerebrospinal fluid concentration of cyclic adenosine-3',5'-monophosphate in various neurological diseases.", "content": "Urinary excretion and cerebrospinal fluid concentration of cyclic adenosine-3',5'-monophosphate in various neurological diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369423"}
{"pmid": "4369424", "title": "Use of benzoylated cellulose columns for the isolation of poly(adenylic acid) containing RNA and other polynucleotides with little secondary structure.", "content": "Use of benzoylated cellulose columns for the isolation of poly(adenylic acid) containing RNA and other polynucleotides with little secondary structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369424"}
{"pmid": "4369425", "title": "Use of immune lymphocytes to detect expression of herpetic genome.", "content": "Use of immune lymphocytes to detect expression of herpetic genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369425"}
{"pmid": "4369426", "title": "Utilization of ascites plasma very low density lipoprotein triglycerides by Ehrlich cells.", "content": "Utilization of ascites plasma very low density lipoprotein triglycerides by Ehrlich cells. Much of the lipid present in the ascites plasma in which Ehrlich cells grow is contained in very low density lipoproteins (VLDL). Chemical measurements indicated that triglycerides were taken up by the cells during in vitro incubation with ascites VLDL. When tracer amounts of radioactive triolein were incorporated into the ascites VLDL, the percentage uptakes of glyceryl tri[1-(14)C]oleate and triglycerides measured chemically were similar. The cells also took up [2-(3)H]glyceryl trioleate that was added to VLDL, but the percentage of available (3)H recovered in the cell lipids was 30-40% less than that of (1 4)C from glyceryl tri[1-(1 4)C]oleate. This difference was accounted for by water-soluble (3)H that accumulated in the incubation medium, suggesting that extensive hydrolysis accompanied the uptake of VLDL triglycerides. Radioactive fatty acids derived from the VLDL triglycerides were incorporated into cell phospholipids, glycerides, and free fatty acids, and they also were oxidized to CO(2). Triglyceride utilization increased as the VLDL concentration was raised. These results suggest that one function of the ascites plasma VLDL may be to supply fatty acid to the Ehrlich cells and that the availability of fatty acid to this tumor is determined in part by the ascites plasma VLDL concentration. Although Ehrlich cells incorporate almost no free glycerol into triglycerides, considerable amounts of [2-(3)H]glyceryl trioleate radioactivity were recovered in cell triglycerides. This indicates that at least some VLDL triglycerides were taken up intact. The net uptake of VLDL protein and cholesterol was very small relative to the triglyceride uptake, suggesting that intact triglycerides are transferred from the ascites VLDL to the Ehrlich cells and that hydrolysis occurs after the triglyceride is associated with the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369426"}
{"pmid": "4369427", "title": "Uveitis, episcleritis and conjunctivitis associated with Yersinia infection.", "content": "Uveitis, episcleritis and conjunctivitis associated with Yersinia infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369427"}
{"pmid": "4369428", "title": "Vacuolar transcellular channels as a drainage pathway for cerebrospinal fluid.", "content": "Vacuolar transcellular channels as a drainage pathway for cerebrospinal fluid. 1. Based on our ultrastructural investigations in monkeys, we report here a new concept as to the physiological mechanism of drainage of cerebrospinal fluid (c.s.f.) which would seem to bridge the gap between the two apparently opposing views of ;closed' and ;open' system.2. Our studies reveal the presence of an intact mesothelial lining of the arachnoid mater, including its villus-like projections and herniations into the dural sinus and its lacunae, adjacent cells being joined by tight junctions; in addition we have observed for the first time that many lining cells in the region of the superior sagittal sinus are characterized by unit membrane-bound, electron-optically empty giant vacuoles of several micrometres diameter. In one monkey with a fresh subarachnoid haemorrhage, many vacuoles were filled with plasma proteins and some contained intact blood corpuscles.3. Serial section analysis showed that the vacuoles were in fact invaginations from the basal aspect of the cell surface and were evidently in direct communication with the c.s.f. in the subarachnoid space. Some vacuoles in addition showed openings on their apical surface thus constituting transcellular channels or pores. Basal openings up to 3.5 mum and apical openings up to 2.3 mum were seen.4. It is postulated that vacuoles are stages in the formation of a dynamic system of transcellular pores which allow the bulk outflow of c.s.f. down a pressure gradient, and that the mesothelial vacuolation cycle, in providing the requisite number of transcellular pores across the mesothelial barrier at any time, is a controlling factor in the outflow of c.s.f. and in the maintenance of its fluid-pressure within the subarachnoid space.5. The basic similarity between the bulk flow of the aqueous humour and c.s.f. from the anatomically closed cavities of the anterior chamber and the subarachnoid space, respectively, is underlined.6. The present study provides further support for our hypothesis that the bulk outflow of fluid, via a dynamic system of transcellular pores formed by gradually enlarging membranous surface infoldings in a single cell, termed as giant vacuoles, is a fundamental biological process not hitherto described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369428"}
{"pmid": "4369430", "title": "Variability of sleep measures in normal subjects.", "content": "Variability of sleep measures in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369430"}
{"pmid": "4369422", "title": "Unusual metastatic sites of colonic and rectal carcinoma: Report of four cases.", "content": "Unusual metastatic sites of colonic and rectal carcinoma: Report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369422"}
{"pmid": "4369429", "title": "Value of aortography in the diagnosis of congenital multicystic kidney.", "content": "Value of aortography in the diagnosis of congenital multicystic kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369429"}
{"pmid": "4369432", "title": "Vascular intimal components: precursors of thrombosis.", "content": "Vascular intimal components: precursors of thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369432"}
{"pmid": "4369433", "title": "Vascular responsiveness of the in situ perfused dog pancreas.", "content": "Vascular responsiveness of the in situ perfused dog pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369433"}
{"pmid": "4369435", "title": "Ventilation and sleep state in the new-born.", "content": "Ventilation and sleep state in the new-born. 1. Ventilation, oesophageal pressure and sleep state were measured in fourteen babies between 25 hr and 7 days of age.2. Trunk plethysmograph records showed that respiratory rate and minute volume were significantly higher in REM sleep than non-REM sleep. Tidal volume was not significantly altered.3. Tidal volume, respiratory rate and minute volume were all more variable in each baby in REM sleep, both on breath to breath analysis and over successive 20 sec periods.4. Major oesophageal peristaltic activity was observed in REM sleep only.5. In response to a sharp rise in P(O2) the tidal volume and minute volume fell significantly by the same proportion in both sleep states. Respiratory rate did not change significantly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369435"}
{"pmid": "4369436", "title": "Viability of swine vesicular disease in carcases and faeces.", "content": "Viability of swine vesicular disease in carcases and faeces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369436"}
{"pmid": "4369431", "title": "Vascular characteristics of unilateral acute renal failure in the dog. Assessment with vasodilators and antagonists to angiotensin and norepinephrine.", "content": "Vascular characteristics of unilateral acute renal failure in the dog. Assessment with vasodilators and antagonists to angiotensin and norepinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369431"}
{"pmid": "4369434", "title": "Vasoactive intestinal peptide stimulation of adenylate cyclase and active electrolyte secretion in intestinal mucosa.", "content": "Vasoactive intestinal peptide stimulation of adenylate cyclase and active electrolyte secretion in intestinal mucosa. Vasoactive intestinal peptide (VIP), originally isolated from hog small intestinal mucosa, has been shown to cause small intestinal secretion. More recently, this peptide has been identified in the plasma and tumors of patients with the so-called \"pancreatic cholera\" syndrome. In order to explore the possible role of VIP in the pathogenesis of this syndrome, we examined the effects of this peptide and other hormones on the cyclic AMP levels, adenylate cyclase activity, and ion transport in in vitro preparations of ileal mucosa. In rabbit ileal mucosa, VIP (20 mug/ml) caused a prompt fivefold increase in cyclic AMP level, whereas nine other hormones, which have been postulated to cause intestinal secretion, failed to exert such an effect. Pentagastrin and glucagon also failed to increase cyclic AMP levels in canine ileal mucosa. An increase in mucosal cyclic AMP levels was observed at a VIP concentration of 0.1 mug/ml and appeared to be nearly maximal at 2.0 mug/ml. VIP (100 mug/ml) stimulated adenylate cyclase activity in a membrane preparation from rabbit ileal mucosa. Secretin (6.0 x 10(-5) M) failed to do so. When added to the serosal side of isolated rabbit ileal mucosa clamped in an Ussing chamber, VIP (2 mug/ml) increased short-circuit current (SCC) and caused net secretion of both Cl and Na. Net Cl secretion exceeded net Na secretion. These effects of VIP on mucosal cyclic AMP metabolism and ion transport are similar to those observed with cholera enterotoxin and certain prostaglandins. VIP was also tested with normal human ileal mucosa. At a concentration of 2 mug/ml it caused a fivefold increase in cyclic AMP level and an increase in SCC of the same magnitude as that caused by 5 mM theophylline. Addition of a second 2-mug/ml dose of VIP and addition of theophylline after VIP produced no further change in SCC. We conclude the VIP stimulates adenylate cyclase and active ion secretion in both rabbit and human ileal mucosa. This may be related to the pathogenesis of diarrhea in patients with the pancreatic cholera syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369434"}
{"pmid": "4369437", "title": "Villous adenoma of the colon and rectum: an ultrastructural study.", "content": "Villous adenoma of the colon and rectum: an ultrastructural study. The villous component of nine colonic polyps (three pure villous adenoma and six mixed adenomatous and villous adenomas) was studied by light and electron microscopy. Normal colonic mucosa was used for control. The predominant cell was an undifferentiated epithelial cell resembling those of the base of the crypts of normal colonic mucosa. A minority of these cells differentiated toward goblet cells and absorptive cells. Interdigitations of the plasma membrane with enlarged intercellular spaces were frequently observed, possibly related to the loss of water and electrolytes in some of these tumors, suggesting an analogy to renal tubular plasma membrane changes in kalliopenic nephropathy. Numerous membrane-bound, inter and intracellular \"inclusion bodies\" representing degenerated lymphocytes and epithelial cell organelles were commonly found. Viral inclusions were not detected in this material. The possibility that the inclusion bodies observed in villous adenoma may represent lysosome-modified vesicles, secondary to absorption of protein and surface mucosubstances appears unlikely.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369437"}
{"pmid": "4369439", "title": "Virus infection and incidence of respiratory disease: a serological study of four micro-organisms at a large beef-rearing farm.", "content": "Virus infection and incidence of respiratory disease: a serological study of four micro-organisms at a large beef-rearing farm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369439"}
{"pmid": "4369440", "title": "Virus-specific proteins associated with ribosomes of Krebs-II cells infected with encephalomyocarditis virus.", "content": "Virus-specific proteins associated with ribosomes of Krebs-II cells infected with encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369440"}
{"pmid": "4369441", "title": "Viruses and the immune response.", "content": "Viruses and the immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369441"}
{"pmid": "4369438", "title": "Viral teratology.", "content": "Viral teratology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369438"}
{"pmid": "4369442", "title": "Vitamin D hormones. 2.", "content": "Vitamin D hormones. 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369442"}
{"pmid": "4369443", "title": "Vitamin D hormones: 1.", "content": "Vitamin D hormones: 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369443"}
{"pmid": "4369444", "title": "Water pollution. Microbiology--detection, occurrence, and removal of viruses.", "content": "Water pollution. Microbiology--detection, occurrence, and removal of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369444"}
{"pmid": "4369445", "title": "What is analgesia?", "content": "What is analgesia?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369445"}
{"pmid": "4369446", "title": "Wilms's tumour--an improved prognosis. Report of 22 consecutive children seen from 1967-71.", "content": "Wilms's tumour--an improved prognosis. Report of 22 consecutive children seen from 1967-71.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369446"}
{"pmid": "4369448", "title": "X-ray small angle scattering of human plasma high density lipoprotein LpA from HDL2: application of a new evaluation method.", "content": "X-ray small angle scattering of human plasma high density lipoprotein LpA from HDL2: application of a new evaluation method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369448"}
{"pmid": "4369447", "title": "X-ray diffraction studies of DNA at reduced water contents.", "content": "X-ray diffraction studies of DNA at reduced water contents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369447"}
{"pmid": "4369450", "title": "1,N6-etheno-2-aza-adenosine 3',5'-monophosphate: a new fluorescent substrate for cycle nucleotide phosphodiesterase.", "content": "1,N6-etheno-2-aza-adenosine 3',5'-monophosphate: a new fluorescent substrate for cycle nucleotide phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369450"}
{"pmid": "4369449", "title": "Xanthine oxidase deficiency: studies of a previously unreported case.", "content": "Xanthine oxidase deficiency: studies of a previously unreported case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369449"}
{"pmid": "4369451", "title": "1H nuclear magnetic resonance studies of thyrotropin releasing factor (TRF).", "content": "1H nuclear magnetic resonance studies of thyrotropin releasing factor (TRF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369451"}
{"pmid": "4369452", "title": "2',3'-Cyclic nucleotide 3'-phosphohydrolase activity in human brain tumours.", "content": "2',3'-Cyclic nucleotide 3'-phosphohydrolase activity in human brain tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369452"}
{"pmid": "4369453", "title": "270 MHz proton magnetic resonance spectra of metallothionein.", "content": "270 MHz proton magnetic resonance spectra of metallothionein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369453"}
{"pmid": "4369454", "title": "3' End-group labeling and partial sequence determination of oligodeoxynucleotides.", "content": "3' End-group labeling and partial sequence determination of oligodeoxynucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369454"}
{"pmid": "4369455", "title": "5'-Terminal nucleotide sequences of the double-stranded RNA of silkworm cytoplasmic polyhedrosis virus.", "content": "5'-Terminal nucleotide sequences of the double-stranded RNA of silkworm cytoplasmic polyhedrosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369455"}
{"pmid": "4369456", "title": "6-O-methyl-D-glucosamine in lipopolysaccharides of Rhodopseudomonas palustris strains.", "content": "6-O-methyl-D-glucosamine in lipopolysaccharides of Rhodopseudomonas palustris strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369456"}
{"pmid": "4369457", "title": "8 alpha-substituted flavins of biological importance.", "content": "8 alpha-substituted flavins of biological importance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369457"}
{"pmid": "4369458", "title": "On the hypothalamic regulation of the adenohypophysial gonadotropic function.", "content": "On the hypothalamic regulation of the adenohypophysial gonadotropic function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369458"}
{"pmid": "4369461", "title": "Probable sites for estrogen receptors in brain and pituitary.", "content": "Probable sites for estrogen receptors in brain and pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369461"}
{"pmid": "4369459", "title": "Symptomatology of early maturing girls.", "content": "Symptomatology of early maturing girls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369459"}
{"pmid": "4369463", "title": "(R,S)-2,3-epoxypropyl ethers and glycosides of D-glucopyranose.", "content": "(R,S)-2,3-epoxypropyl ethers and glycosides of D-glucopyranose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369463"}
{"pmid": "4369464", "title": "c-AMP phosphodiesterase activity during growth and differentiation in Blastocladiella emersonii.", "content": "c-AMP phosphodiesterase activity during growth and differentiation in Blastocladiella emersonii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369464"}
{"pmid": "4369465", "title": "p-Nitrophenylphosphatase in denervated muscle.", "content": "p-Nitrophenylphosphatase in denervated muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369465"}
{"pmid": "4369534", "title": "[Diagnosis, surgical and radiotherapeutic treatment of malignant tumors of the upper jaw].", "content": "[Diagnosis, surgical and radiotherapeutic treatment of malignant tumors of the upper jaw].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369534"}
{"pmid": "4369620", "title": "[Mixed mesodermal tumor of the uterine corpus in a 4-year-old girl].", "content": "[Mixed mesodermal tumor of the uterine corpus in a 4-year-old girl].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369620"}
{"pmid": "4369712", "title": "A case of atrial myxoma.", "content": "A case of atrial myxoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369712"}
{"pmid": "4369714", "title": "A comparative study of some properties of chromatin from normal diploid and SV-40 transformed human fibroblasts.", "content": "A comparative study of some properties of chromatin from normal diploid and SV-40 transformed human fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369714"}
{"pmid": "4369713", "title": "A column procedure for the esterification of organic acids with diazomethane at the microgram level.", "content": "A column procedure for the esterification of organic acids with diazomethane at the microgram level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369713"}
{"pmid": "4369715", "title": "A comparison of renin and erythropoietin levels in anephric man.", "content": "A comparison of renin and erythropoietin levels in anephric man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369715"}
{"pmid": "4369716", "title": "A cytogenetic investigation of blood lymphocytes in chronic forms of virus hepatitis.", "content": "A cytogenetic investigation of blood lymphocytes in chronic forms of virus hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369716"}
{"pmid": "4369717", "title": "A direct, stimulating effect of cyclic GMP on purified phosphoribosyl pyrophosphate synthetase and its antagonism by cyclic AMP.", "content": "A direct, stimulating effect of cyclic GMP on purified phosphoribosyl pyrophosphate synthetase and its antagonism by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369717"}
{"pmid": "4369718", "title": "A fluorescent method for the demonstration of cyclic 3',5'-AMP phosphodiesterase activity in polyacrylamide gel.", "content": "A fluorescent method for the demonstration of cyclic 3',5'-AMP phosphodiesterase activity in polyacrylamide gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369718"}
{"pmid": "4369719", "title": "A highly sensitive in vitro bioassay for luteinizing hormone and chorionic gonadotropin: testosterone production by dispersed Leydig cells.", "content": "A highly sensitive in vitro bioassay for luteinizing hormone and chorionic gonadotropin: testosterone production by dispersed Leydig cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369719"}
{"pmid": "4369720", "title": "A method for determination of saturated phosphatidylcholine.", "content": "A method for determination of saturated phosphatidylcholine. Phosphatidylcholine preparations containing saturated and unsaturated molecular species were subjected to KMnO(4)-NaIO(4) oxidation in aqueous acetic acid, which left only disaturated species intact. After the oxidation, the remaining intact phosphatidylcholine was separated by thin-layer chromatography. The procedure could be used as a simple and rapid method for microdetermination of the saturated species in phosphatidylcholine preparations containing more than 0.1 micro mole of the saturated species. The contents of the saturated species in native phosphatidylcholines obtained from rat lung tissue and washings by this procedure were 35.7% and 58.3%, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369720"}
{"pmid": "4369721", "title": "A method for determination of the methylated constituents of transfer ribonucleic acid.", "content": "A method for determination of the methylated constituents of transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369721"}
{"pmid": "4369722", "title": "A method for quantitative determination of the abnormal lipoprotein of cholestasis, LP-X.", "content": "A method for quantitative determination of the abnormal lipoprotein of cholestasis, LP-X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369722"}
{"pmid": "4369723", "title": "A new approach to the isolation of RNA-DNA hybrids and its application to the quantitative determination of labeled tumor virus RNA.", "content": "A new approach to the isolation of RNA-DNA hybrids and its application to the quantitative determination of labeled tumor virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369723"}
{"pmid": "4369724", "title": "A new form of acute conjunctivitis epidemic in Taiwan. A simultaneous outbreak of adenovirus type II and \"acute hemorrhagic conjunctivitis\" virus infections.", "content": "A new form of acute conjunctivitis epidemic in Taiwan. A simultaneous outbreak of adenovirus type II and \"acute hemorrhagic conjunctivitis\" virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369724"}
{"pmid": "4369725", "title": "A new form of beta-thalassemia trait.", "content": "A new form of beta-thalassemia trait.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369725"}
{"pmid": "4369727", "title": "A new method for radionuclide imaging of acute myocardial infarction in humans.", "content": "A new method for radionuclide imaging of acute myocardial infarction in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369727"}
{"pmid": "4369729", "title": "A rapid gas chromatographic-mass spectrometric method for prostaglandin analysis at picomole levels.", "content": "A rapid gas chromatographic-mass spectrometric method for prostaglandin analysis at picomole levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369729"}
{"pmid": "4369731", "title": "A seroepidemiological study of herpes simplex virus.", "content": "A seroepidemiological study of herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369731"}
{"pmid": "4369728", "title": "A potent interferon inducer derived from poly (7-deazainosinic acid).", "content": "A potent interferon inducer derived from poly (7-deazainosinic acid).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369728"}
{"pmid": "4369732", "title": "A spin-label study of the photosynthetic bacterium, Rhodospirillum rubrum; Reduction and regeneration of nitroxide spin-labels.", "content": "A spin-label study of the photosynthetic bacterium, Rhodospirillum rubrum; Reduction and regeneration of nitroxide spin-labels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369732"}
{"pmid": "4369733", "title": "A study of associated factors, including genital herpes, in Black women with cervical carcinoma in Johannesburg.", "content": "A study of associated factors, including genital herpes, in Black women with cervical carcinoma in Johannesburg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369733"}
{"pmid": "4369734", "title": "A study of auditory evoked responses during sleep.", "content": "A study of auditory evoked responses during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369734"}
{"pmid": "4369726", "title": "A new hypothesis for the evolution of biological electron transport.", "content": "A new hypothesis for the evolution of biological electron transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369726"}
{"pmid": "4369736", "title": "A study of pyruvate-induced inhibition in the dogfish lactate dehydrogenase system. Mechanistic comparison with the iodination of pyruvate.", "content": "A study of pyruvate-induced inhibition in the dogfish lactate dehydrogenase system. Mechanistic comparison with the iodination of pyruvate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369736"}
{"pmid": "4369739", "title": "A thermodynamic characterisation of the cytochromes of chromatophores from Rhodopseudomonas capsulata.", "content": "A thermodynamic characterisation of the cytochromes of chromatophores from Rhodopseudomonas capsulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369739"}
{"pmid": "4369737", "title": "A study on cataplexy.", "content": "A study on cataplexy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369737"}
{"pmid": "4369740", "title": "Abrogation of resistance to bone marrow grafts by silica particles. Prevention of the silica effect by the macrophage stabilizer poly-2-vinylpyridine N-oxide.", "content": "Abrogation of resistance to bone marrow grafts by silica particles. Prevention of the silica effect by the macrophage stabilizer poly-2-vinylpyridine N-oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369740"}
{"pmid": "4369741", "title": "Acetolysis of dextran NRRL b1397. Preparation of trisaccharides containing (1 leads to 2)- and (1 leads to 6)-alpha-D-glucose linkages.", "content": "Acetolysis of dextran NRRL b1397. Preparation of trisaccharides containing (1 leads to 2)- and (1 leads to 6)-alpha-D-glucose linkages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369741"}
{"pmid": "4369742", "title": "Achilles tendinitis and tenosynovitis. A diagnostic manifestation of familial type II hyperlipoproteinemia in children.", "content": "Achilles tendinitis and tenosynovitis. A diagnostic manifestation of familial type II hyperlipoproteinemia in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369742"}
{"pmid": "4369743", "title": "Acrodermatitis enteropathica associated with low density lipoproteins deficiency.", "content": "Acrodermatitis enteropathica associated with low density lipoproteins deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369743"}
{"pmid": "4369735", "title": "A study of methods of identification and estimation of Lp(a) lipoprotein and of its significance in health, hyperlipidaemia and atherosclerosis.", "content": "A study of methods of identification and estimation of Lp(a) lipoprotein and of its significance in health, hyperlipidaemia and atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369735"}
{"pmid": "4369744", "title": "Action of alpha-1,6-glucan glucohydrolase on oligosaccharides derived from dextran.", "content": "Action of alpha-1,6-glucan glucohydrolase on oligosaccharides derived from dextran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369744"}
{"pmid": "4369745", "title": "Action of peptides and other algesic agents on paravascular pain receptors of the isolated perfused rabbit ear.", "content": "Action of peptides and other algesic agents on paravascular pain receptors of the isolated perfused rabbit ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369745"}
{"pmid": "4369746", "title": "Activation of glycogenolysis in perfused rat livers by glucagon and metabolic inhibitors.", "content": "Activation of glycogenolysis in perfused rat livers by glucagon and metabolic inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369746"}
{"pmid": "4369747", "title": "Activation of lordosis in ovariectomized guinea pigs by free and esterified forms of estrone, estradiol-17 beta and estriol.", "content": "Activation of lordosis in ovariectomized guinea pigs by free and esterified forms of estrone, estradiol-17 beta and estriol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369747"}
{"pmid": "4369748", "title": "Activation of pea leaf chloroplast sedoheptulose 1,7-diphosphate phosphatase by light and dithiothreitol.", "content": "Activation of pea leaf chloroplast sedoheptulose 1,7-diphosphate phosphatase by light and dithiothreitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369748"}
{"pmid": "4369749", "title": "Activation of simian virus 40 by transfer of isolated chromosomes from transformed cells.", "content": "Activation of simian virus 40 by transfer of isolated chromosomes from transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369749"}
{"pmid": "4369750", "title": "Active site chloride binding in liver alcohol dehydrogenase.", "content": "Active site chloride binding in liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369750"}
{"pmid": "4369752", "title": "Acute effects of ozone on cat lungs. II. Structural.", "content": "Acute effects of ozone on cat lungs. II. Structural.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369752"}
{"pmid": "4369751", "title": "Active transport of iodide and other anions across the choroid plexus.", "content": "Active transport of iodide and other anions across the choroid plexus. 1. An in vitro preparation of the frog choroid plexus was used to study mechanisms of anion transport.2. It was observed that, in the absence of electrochemical potential gradients, there were net fluxes of I(-), SCN(-), TcO(4) (-), and Br(-) across the plexus, from the ventricular to the serosal surface. The net flux of I(-) reached a maximum at a concentration of 250 muM.3. On the basis of competition effects it was concluded that the affinity of the transport process for anions was: ClO(4) > ReO(4) approximately BF(4) > SCN approximately SeCN > I > NO(3) > Br > Cl.4. Ouabain, oligomycin, phloretin and 2,4-DNP inhibited the net transport of anions, but phlorrhizin, furosemide, 2,4,6-trinitro-m-cresolate, reducing agents, and antithyroid agents did not. Ouabain and phloretin were only effective on the ventricular side of the preparation.5. Anion transport required the presence of both Na and K. The requirement for Na was specific, but Rb, and to a lesser extent Cs, could substitute for K. Na in either the ventricular or the serosal fluids could partially stimulate anion transport, but K was only effective in the ventricular solution.6. TcO(4) (-), SCN(-) and I(-) were accumulated within the choroidal epithelium from the ventricular fluid, but not from the serosal fluid. Accumulation was inhibited by ouabain and ClO(4) (-).7. The unidirectional influx of I(-) across the apical cell membrane was about an order of magnitude greater than the flux across the epithelium. This flux was inhibited by ClO(4) (-), ouabain, and Na-free solutions.8. These experiments suggest the following mechanism for anion transport across the plexus: anions are actively transported into the epithelium, by a ouabain sensitive, Na/K dependent pump located in the brush border membrane. The anions are accumulated within the epithelium, and, finally, they pass into the serosal fluid down their electrochemical potential gradient. Relations between anion transport, Na/K transport, and Na/K ATPases are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369751"}
{"pmid": "4369753", "title": "Acute respiratory infections.", "content": "Acute respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369753"}
{"pmid": "4369754", "title": "Adenosine 3',5'-monophosphate in amniotic fluid from pregnancy complicated by hypertension.", "content": "Adenosine 3',5'-monophosphate in amniotic fluid from pregnancy complicated by hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369754"}
{"pmid": "4369755", "title": "Adenosine 3':5'-monophosphate and hormone interrelationships in the mammary gland of the rat during pregnancy and lactation.", "content": "Adenosine 3':5'-monophosphate and hormone interrelationships in the mammary gland of the rat during pregnancy and lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369755"}
{"pmid": "4369756", "title": "Adenosine 3':5'-monophosphate dependent protein kinase isolated from rat Harderian gland.", "content": "Adenosine 3':5'-monophosphate dependent protein kinase isolated from rat Harderian gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369756"}
{"pmid": "4369758", "title": "Adenylate kinase from Pseudomonas denitrificans. I. Purification and antiserum inhibition.", "content": "Adenylate kinase from Pseudomonas denitrificans. I. Purification and antiserum inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369758"}
{"pmid": "4369757", "title": "Adenosine 3':5'-monophosphate-dependent protein kinase and the stimulation of ovarian nuclear ribonucleic acid polymerase activities.", "content": "Adenosine 3':5'-monophosphate-dependent protein kinase and the stimulation of ovarian nuclear ribonucleic acid polymerase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369757"}
{"pmid": "4369759", "title": "Adrenal cells in tissue culture. The effect of papaverine and amytal on steroidogenesis, respiration and replication.", "content": "Adrenal cells in tissue culture. The effect of papaverine and amytal on steroidogenesis, respiration and replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369759"}
{"pmid": "4369760", "title": "Adrenergic stimulation of phosphatidylinositol labelling in rat vas deferens.", "content": "Adrenergic stimulation of phosphatidylinositol labelling in rat vas deferens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369760"}
{"pmid": "4369761", "title": "Adrenoceptors and bronchial asthma.", "content": "Adrenoceptors and bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369761"}
{"pmid": "4369762", "title": "Adrenocortical control of monoamine oxidase activity in the ground squirrel (Citellus citellus) during the winter.", "content": "Adrenocortical control of monoamine oxidase activity in the ground squirrel (Citellus citellus) during the winter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369762"}
{"pmid": "4369763", "title": "Adrenocorticotrophic and growth hormone secretion. Studies during pneumoencephalography.", "content": "Adrenocorticotrophic and growth hormone secretion. Studies during pneumoencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369763"}
{"pmid": "4369765", "title": "Affinity chromatography purification of diphtheria toxin.", "content": "Affinity chromatography purification of diphtheria toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369765"}
{"pmid": "4369766", "title": "Affinity of murine and human interferon for concanavalin A.", "content": "Affinity of murine and human interferon for concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369766"}
{"pmid": "4369767", "title": "Agonist and antagonist relationships in 1- and 8-substituted analogs of angiotensin II.", "content": "Agonist and antagonist relationships in 1- and 8-substituted analogs of angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369767"}
{"pmid": "4369764", "title": "Aetiology of hyperthyroidism. II.", "content": "Aetiology of hyperthyroidism. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369764"}
{"pmid": "4369768", "title": "Algesic actions of the polypeptides and other agents.", "content": "Algesic actions of the polypeptides and other agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369768"}
{"pmid": "4369769", "title": "Allergenic glucans from dermatophytes. I. Isolation, purification, and biological properties.", "content": "Allergenic glucans from dermatophytes. I. Isolation, purification, and biological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369769"}
{"pmid": "4369770", "title": "An electron microscopy study of the effects on dibutyryl cyclic AMP on Chinese hamster ovary cells.", "content": "An electron microscopy study of the effects on dibutyryl cyclic AMP on Chinese hamster ovary cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369770"}
{"pmid": "4369771", "title": "An epidemiologic study of breast cancer.", "content": "An epidemiologic study of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369771"}
{"pmid": "4369772", "title": "An epizootic of Sendai infection with mortality in a barrier-maintained mouse colony.", "content": "An epizootic of Sendai infection with mortality in a barrier-maintained mouse colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369772"}
{"pmid": "4369774", "title": "An extra species of lysine transfer ribonucleic acid in polyoma virus-transformed cells in tissue culture.", "content": "An extra species of lysine transfer ribonucleic acid in polyoma virus-transformed cells in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369774"}
{"pmid": "4369773", "title": "An estrogen binding protein in the renal cytosol of intact, castrated and estrogenized golden hamsters.", "content": "An estrogen binding protein in the renal cytosol of intact, castrated and estrogenized golden hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369773"}
{"pmid": "4369776", "title": "An intracellular alpha-D-glucan from Clostridium botulinum, type E.", "content": "An intracellular alpha-D-glucan from Clostridium botulinum, type E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369776"}
{"pmid": "4369775", "title": "An in-vitro bioassay for prolactin based on stimulation of casein synthesis by a dispersed cell preparation from mouse mammary gland.", "content": "An in-vitro bioassay for prolactin based on stimulation of casein synthesis by a dispersed cell preparation from mouse mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369775"}
{"pmid": "4369778", "title": "An ultrastructural study of alkaline phosphatase activity in normal and neoplastic human salivary glands.", "content": "An ultrastructural study of alkaline phosphatase activity in normal and neoplastic human salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369778"}
{"pmid": "4369777", "title": "An isoenzyme of 5'-nucleotide phosphodiesterase and alpha-fetoprotein in human hepatic cancer patient sera.", "content": "An isoenzyme of 5'-nucleotide phosphodiesterase and alpha-fetoprotein in human hepatic cancer patient sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369777"}
{"pmid": "4369779", "title": "An unusual variant of Klippel-Trenaunay-Weber syndrome.", "content": "An unusual variant of Klippel-Trenaunay-Weber syndrome. The association of soft tissue and bony overgrowth, varicose veins and port-wine nevus is known as Klippel-Trenaunay-Weber syndrome. An unusual case of a young woman with this syndrome is presented. In addition to the classic features she had face swelling, bilateral limb involvement and an infected cutaneous lymphangioma. No evidence of arteriovenous fistula was demonstrated. In contrast to an abnormal lymphatic system the deep veins of the limbs were normal. Unilateral lung lesions were demonstrated which have not been described previously in such cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369779"}
{"pmid": "4369780", "title": "Analysis of the RNA of defective VSV particles.", "content": "Analysis of the RNA of defective VSV particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369780"}
{"pmid": "4369782", "title": "Angioleiomyoma of the skin.", "content": "Angioleiomyoma of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369782"}
{"pmid": "4369781", "title": "Androgen binding proteins in cock's tissues: properties of ear lobe protein and determination of binding sites in head appendages and other tissues.", "content": "Androgen binding proteins in cock's tissues: properties of ear lobe protein and determination of binding sites in head appendages and other tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369781"}
{"pmid": "4369783", "title": "Angiotensin infusion test in the diagnosis of renal hypertension.", "content": "Angiotensin infusion test in the diagnosis of renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369783"}
{"pmid": "4369784", "title": "Anterior interosseous nerve syndrome.", "content": "Anterior interosseous nerve syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369784"}
{"pmid": "4369786", "title": "Antibiotic neurotoxicity. Laboratory and clinical study.", "content": "Antibiotic neurotoxicity. Laboratory and clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369786"}
{"pmid": "4369787", "title": "Antibodies to Epstein-Barr virus-associated nuclear antigen in infectious mononucleosis.", "content": "Antibodies to Epstein-Barr virus-associated nuclear antigen in infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369787"}
{"pmid": "4369788", "title": "Antibody to prolyl hydroxylase from rat skin and its cross-reactivity with enzyme from other species.", "content": "Antibody to prolyl hydroxylase from rat skin and its cross-reactivity with enzyme from other species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369788"}
{"pmid": "4369790", "title": "Application of measurement and control of dissolved oxygen pressure to vaccine production.", "content": "Application of measurement and control of dissolved oxygen pressure to vaccine production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369790"}
{"pmid": "4369789", "title": "Antimicrobial therapy in children.", "content": "Antimicrobial therapy in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369789"}
{"pmid": "4369791", "title": "Application of serum alpha feto-protein assay in mass survey of primary carcinoma of liver. The Co-ordinating Group for the Research of Liver Cancer. People's Republic of China.", "content": "Application of serum alpha feto-protein assay in mass survey of primary carcinoma of liver. The Co-ordinating Group for the Research of Liver Cancer. People's Republic of China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369791"}
{"pmid": "4369792", "title": "Aspects of continuous cultivation of spore-forming microbes from the group Bacillus thuringiensis.", "content": "Aspects of continuous cultivation of spore-forming microbes from the group Bacillus thuringiensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369792"}
{"pmid": "4369785", "title": "Anti-C3d antiglobulin reagents. I. Characteristics of the anti-C3c and anti-C3d responses during hyperimmunization in rabbits.", "content": "Anti-C3d antiglobulin reagents. I. Characteristics of the anti-C3c and anti-C3d responses during hyperimmunization in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369785"}
{"pmid": "4369793", "title": "Atherogenic and thrombogenic mosaic.", "content": "Atherogenic and thrombogenic mosaic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369793"}
{"pmid": "4369794", "title": "Atherosclerosis as a pediatric problem.", "content": "Atherosclerosis as a pediatric problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369794"}
{"pmid": "4369797", "title": "Attitudes and behaviors of acute and chronic schizophrenic patients regarding ambulatory treatment.", "content": "Attitudes and behaviors of acute and chronic schizophrenic patients regarding ambulatory treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369797"}
{"pmid": "4369796", "title": "Attempts to demonstrate the interferon defense mechanism in cultured mosquito cells.", "content": "Attempts to demonstrate the interferon defense mechanism in cultured mosquito cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369796"}
{"pmid": "4369798", "title": "Audiologic evaluation in cochlear and eighth nerve disorders.", "content": "Audiologic evaluation in cochlear and eighth nerve disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369798"}
{"pmid": "4369799", "title": "Autonomous derivatives of estrogen-induced renal carcinomas and spontaneous renal tumors in the Syrian hamster.", "content": "Autonomous derivatives of estrogen-induced renal carcinomas and spontaneous renal tumors in the Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369799"}
{"pmid": "4369800", "title": "Avian myeloblastosis virus DNA polymerase: initiation of DNA synthesis and an associated ribonuclease.", "content": "Avian myeloblastosis virus DNA polymerase: initiation of DNA synthesis and an associated ribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369800"}
{"pmid": "4369803", "title": "Basic rest-activity cycle in the perception of the spiral after-effect; a sensitive detector of a basic biological rhythm.", "content": "Basic rest-activity cycle in the perception of the spiral after-effect; a sensitive detector of a basic biological rhythm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369803"}
{"pmid": "4369802", "title": "Baroreceptor activity and responsiveness to angiotensin in patients with chronic renal failure.", "content": "Baroreceptor activity and responsiveness to angiotensin in patients with chronic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369802"}
{"pmid": "4369801", "title": "ATP-dependent calcium uptake by microsomal fractions of pig coronary artery and its dependence on bradykinin and angiotensin II.", "content": "ATP-dependent calcium uptake by microsomal fractions of pig coronary artery and its dependence on bradykinin and angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369801"}
{"pmid": "4369804", "title": "Bentonite flocculation test for amoebiasis.", "content": "Bentonite flocculation test for amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369804"}
{"pmid": "4369805", "title": "Biliary excretion in vivo of bile acids synthesized by hepatomas.", "content": "Biliary excretion in vivo of bile acids synthesized by hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369805"}
{"pmid": "4369795", "title": "Atherosclerosis in the rhesus monkey fed three food fats.", "content": "Atherosclerosis in the rhesus monkey fed three food fats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369795"}
{"pmid": "4369807", "title": "Binding of spin-labeled local anesthetics to phosphatidylcholine and phosphatidylserine liposomes.", "content": "Binding of spin-labeled local anesthetics to phosphatidylcholine and phosphatidylserine liposomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369807"}
{"pmid": "4369806", "title": "Biliary infections and the chouce of antibiotics.", "content": "Biliary infections and the chouce of antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369806"}
{"pmid": "4369809", "title": "Biochemical and biophysical studies on cytochrome c oxidase. XVIII. Potentiometric titrations of cytochrome c oxidase followed by circular dichroism.", "content": "Biochemical and biophysical studies on cytochrome c oxidase. XVIII. Potentiometric titrations of cytochrome c oxidase followed by circular dichroism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369809"}
{"pmid": "4369808", "title": "Binding of steroids to progesterone receptor proteins in chick oviduct and human uterus.", "content": "Binding of steroids to progesterone receptor proteins in chick oviduct and human uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369808"}
{"pmid": "4369810", "title": "Biochemical neuroendocrinology. I. Biosynthesis of thyrotropin releasing hormone (TRH) by organ cultures of mammalian hypothalamus.", "content": "Biochemical neuroendocrinology. I. Biosynthesis of thyrotropin releasing hormone (TRH) by organ cultures of mammalian hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369810"}
{"pmid": "4369811", "title": "Biochemistry and psychiatry with special reference to psychopharmacology.", "content": "Biochemistry and psychiatry with special reference to psychopharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369811"}
{"pmid": "4369812", "title": "Biogenic amine-containing neurons: biochemical mechanisms of synaptic transmission.", "content": "Biogenic amine-containing neurons: biochemical mechanisms of synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369812"}
{"pmid": "4369813", "title": "Biologic and immunologic comparison of two HSV-2 variants: one an isolate from cervical tumor cells.", "content": "Biologic and immunologic comparison of two HSV-2 variants: one an isolate from cervical tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369813"}
{"pmid": "4369816", "title": "Biosynthesis of 1-alkyl-sn-glycero-3-phosphate via adenosine triphosphate:1-alkyl-sn-glycerol phosphotransferase.", "content": "Biosynthesis of 1-alkyl-sn-glycero-3-phosphate via adenosine triphosphate:1-alkyl-sn-glycerol phosphotransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369816"}
{"pmid": "4369814", "title": "Biosynthesis of cholinesterase in rabbit bone marrow cells in culture.", "content": "Biosynthesis of cholinesterase in rabbit bone marrow cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369814"}
{"pmid": "4369815", "title": "Biosynthesis of glycolipids in virus-transformed cells.", "content": "Biosynthesis of glycolipids in virus-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369815"}
{"pmid": "4369818", "title": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 5. Bis-basic ethers of anthraquinone and bisalkamine esters of anthraquinonedicarboxylic acids.", "content": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 5. Bis-basic ethers of anthraquinone and bisalkamine esters of anthraquinonedicarboxylic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369818"}
{"pmid": "4369817", "title": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 1,2 6. Bis-basic-substituted fluoranthenes.", "content": "Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 1,2 6. Bis-basic-substituted fluoranthenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369817"}
{"pmid": "4369819", "title": "Blastocystis hominis: axenic cultivation.", "content": "Blastocystis hominis: axenic cultivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369819"}
{"pmid": "4369820", "title": "BGM, a continuous cell line more sensitive than primary rhesus and African green kidney cells for the recovery of viruses from water.", "content": "BGM, a continuous cell line more sensitive than primary rhesus and African green kidney cells for the recovery of viruses from water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369820"}
{"pmid": "4369821", "title": "Calciferol and its relatives. XVII. Ring-A components for synthetic work on vitamin D3 and on model compounds.", "content": "Calciferol and its relatives. XVII. Ring-A components for synthetic work on vitamin D3 and on model compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369821"}
{"pmid": "4369822", "title": "Calcitonin secretion in vitro. I. Preparation of monolayer C-cell cultures.", "content": "Calcitonin secretion in vitro. I. Preparation of monolayer C-cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369822"}
{"pmid": "4369823", "title": "Calcium homeostasis and the patogenesis and management of hypercalcemic disorders.", "content": "Calcium homeostasis and the patogenesis and management of hypercalcemic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369823"}
{"pmid": "4369825", "title": "Calibration of a cascade centripeter dust sampler.", "content": "Calibration of a cascade centripeter dust sampler.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369825"}
{"pmid": "4369824", "title": "Calculated equilibria of phosphocreatine and adenosine phosphates during utilization of high energy phosphate by muscle.", "content": "Calculated equilibria of phosphocreatine and adenosine phosphates during utilization of high energy phosphate by muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369824"}
{"pmid": "4369826", "title": "Carbon-13 magnetic resonance assignments of the repeat peptides of elastin and solvent delineation of carbonyls.", "content": "Carbon-13 magnetic resonance assignments of the repeat peptides of elastin and solvent delineation of carbonyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369826"}
{"pmid": "4369827", "title": "Carbon-13 spin-lattice relaxation studies of intramolecular motion in lysine and a series of oligolysines.", "content": "Carbon-13 spin-lattice relaxation studies of intramolecular motion in lysine and a series of oligolysines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369827"}
{"pmid": "4369828", "title": "Carcinoid tumours and cylindromas of the tracheobronchial tree.", "content": "Carcinoid tumours and cylindromas of the tracheobronchial tree.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369828"}
{"pmid": "4369830", "title": "Carcinoma of Skene's gland associated with urethral diverticulum: a case report.", "content": "Carcinoma of Skene's gland associated with urethral diverticulum: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369830"}
{"pmid": "4369829", "title": "Carcinoma of the breast in American Negro men.", "content": "Carcinoma of the breast in American Negro men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369829"}
{"pmid": "4369831", "title": "Cataracts induced by surface active agents.", "content": "Cataracts induced by surface active agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369831"}
{"pmid": "4369832", "title": "Cell cycle dependent transcription of SV40 DNA in SV40-transformed cells.", "content": "Cell cycle dependent transcription of SV40 DNA in SV40-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369832"}
{"pmid": "4369833", "title": "Cell fusion, using Sendai virus, to effect inter-species transfer of a cell-associated parasite (Theileria parva).", "content": "Cell fusion, using Sendai virus, to effect inter-species transfer of a cell-associated parasite (Theileria parva).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369833"}
{"pmid": "4369834", "title": "Cell surface modifications in virus-transformed cells--glycolipid changes in the NIL2 hamster cells.", "content": "Cell surface modifications in virus-transformed cells--glycolipid changes in the NIL2 hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369834"}
{"pmid": "4369836", "title": "Central and reflex regulation of sympathetic vasoconstrictor activity to limb muscles during desynchronized sleep in the cat.", "content": "Central and reflex regulation of sympathetic vasoconstrictor activity to limb muscles during desynchronized sleep in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369836"}
{"pmid": "4369835", "title": "Cellular immunity to herpes simplex virus mediated by interferon.", "content": "Cellular immunity to herpes simplex virus mediated by interferon. Rabbit kidney cell monolayers infected with herpes simplex virus (HSV) were incubated with leukocytes from rabbits immunized with complete Freund's adjuvant. When the leukocytes were exposed to tuberculin purified protein derivative (PPD), viral replication and plaque formation were markedly inhibited. Similarly, when leukocytes from animals immunized with HSV were exposed to UV-inactivated HSV, viral replication was markedly inhibited. Exposure of leukocytes from unimmunized animals or animals immunized with incomplete Freund's adjuvant to UV-inactivated virus or PPD produced relatively little inhibition of viral replication. Examination of supernatant fluids from stimulated cultures revealed a soluble mediator that had the properties of interferon. Interferon production was detected within several hours after exposure of sensitized leukocytes to antigen. Supernatant fluids from as few as one sensitized leukocyte per 200 rabbit kidney cells inhibited HSV replication by over 90%. These findings support the concept that the cellular immune response to HSV consists of two phases: an immunologically specific antigen recognition phase, and a nonspecific effector phase that stops HSV spread by generating interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369835"}
{"pmid": "4369837", "title": "Cerebral metastatic disease in childhood.", "content": "Cerebral metastatic disease in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369837"}
{"pmid": "4369838", "title": "Cerebrospinal fluid concentration of cyclic adenosine-3',5'-monophosphate and pneumoencephalography.", "content": "Cerebrospinal fluid concentration of cyclic adenosine-3',5'-monophosphate and pneumoencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369838"}
{"pmid": "4369839", "title": "Certain biochemical and ultrastructural features of the ventricular myocardium following cardiac denervation.", "content": "Certain biochemical and ultrastructural features of the ventricular myocardium following cardiac denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369839"}
{"pmid": "4369840", "title": "Change in the pituitary-adrenal function of silver foxes during selection according to behavior.", "content": "Change in the pituitary-adrenal function of silver foxes during selection according to behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369840"}
{"pmid": "4369842", "title": "Changes in conformation of stereocilia in hair cells of the rat spiral organ of Corti after 6-hydroxydopamine as revealed by scanning electron microscopy.", "content": "Changes in conformation of stereocilia in hair cells of the rat spiral organ of Corti after 6-hydroxydopamine as revealed by scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369842"}
{"pmid": "4369841", "title": "Changes in chromatin proteins during liver regeneration.", "content": "Changes in chromatin proteins during liver regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369841"}
{"pmid": "4369843", "title": "Changes in the properties of the resident L virus in somatic cell hybrid lines.", "content": "Changes in the properties of the resident L virus in somatic cell hybrid lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369843"}
{"pmid": "4369844", "title": "Characteristics of sodium flux from serosa to mucosa in rabbit ileum.", "content": "Characteristics of sodium flux from serosa to mucosa in rabbit ileum. Sodium flux from serosa to mucosa, J(sm) (Na) in rabbit ileum in vitro has been studied as a function of applied electrical potential at equal sodium concentrations in the bathing solutions. The results indicate that J(sm) (Na) involves two pathways, a diffusional flux through a paracellular shunt pathway and a flux that is independent of applied potential and presumably involves a transcellular pathway. The latter pathway comprises approximately 25 % of J(sm) (Na) in Ringer's solution containing 10 mM glucose and 25 mM bicarbonate. It is stimulated significantly by theophylline unaffected by removal of glucose or addition of ouabain but is reduced to negligible values by anoxia, dinitrophenol, and replacement of all chloride and bicarbonate by isethionate. Thus this component of J(sm) (Na) has a number of characteristics consistent with involvement in a specific secretory process mediating an electrically neutral secretory transport of sodium plus anion from serosa to mucosa. In addition to stimulating this process, theophylline significantly reduced the permeability of the paracellular shunt pathway to sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369844"}
{"pmid": "4369845", "title": "Characteristics of the cyclic 3',5'-AMP formation in isolated ovarian follicles from PMSG-treated immature rats after stimulation in vitro with gonadotrophins and prostaglandins.", "content": "Characteristics of the cyclic 3',5'-AMP formation in isolated ovarian follicles from PMSG-treated immature rats after stimulation in vitro with gonadotrophins and prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369845"}
{"pmid": "4369846", "title": "Characterization and properties of progesterone-binding components in human endometrium.", "content": "Characterization and properties of progesterone-binding components in human endometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369846"}
{"pmid": "4369847", "title": "Characterization of a hormone receptor defect in the androgen-insensitivity mutant.", "content": "Characterization of a hormone receptor defect in the androgen-insensitivity mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369847"}
{"pmid": "4369848", "title": "Characterization of a normal, tissular antigen extracted from human colonic tumors.", "content": "Characterization of a normal, tissular antigen extracted from human colonic tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369848"}
{"pmid": "4369849", "title": "Characterization of defective interfering viral particles present in a population of pseudorabies virions.", "content": "Characterization of defective interfering viral particles present in a population of pseudorabies virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369849"}
{"pmid": "4369850", "title": "Characterization of multiplication of embryo-adapted avian encephalomyelitis virus in chick embryo brain cell cultures.", "content": "Characterization of multiplication of embryo-adapted avian encephalomyelitis virus in chick embryo brain cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369850"}
{"pmid": "4369851", "title": "Characterization of the active site structures of arginine kinase-substrate complexes. Water proton magnetic relaxation rates and electron paramagnetic resonance spectra of manganous-enzyme complexes with substrates and of a transition state analog.", "content": "Characterization of the active site structures of arginine kinase-substrate complexes. Water proton magnetic relaxation rates and electron paramagnetic resonance spectra of manganous-enzyme complexes with substrates and of a transition state analog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369851"}
{"pmid": "4369852", "title": "Characterization of the plasma lipoproteins of the genetically obese hyperlipoproteinemic Zucker fatty rat.", "content": "Characterization of the plasma lipoproteins of the genetically obese hyperlipoproteinemic Zucker fatty rat. The plasma lipoproteins of the Zucker fatty rat were characterized with respect to lipid and apoprotein composition, and results were compared with those obtained from lean controls. Information on apoproteins was obtained from gel filtration experiments and electrophoresis on polyacrylamide gels. Very low density lipoproteins (VLDL) were increased several-fold in fatties, and 78% of their mass was triglycerides compared with 60% in the controls. Low density (LDL) and high density (HDL) lipoproteins were increased by a factor of 2, although their compositions were similar to those of the controls. Levels of apoVLDL, apoLDL, and apoHDL were five, two and two times higher, respectively, in the fatties, and the two most rapidly moving subunit peptides on polyacrylamide gels were disproportionately elevated in the apoproteins. The slower of these two bands was present in relatively greater amounts than the faster one in fatties. If the slower peptide is an activator of lipoprotein lipase, analogous to the comparable subunit peptides of human apolipoproteins, plasmas of fatties could contain up to 10 times more lipase activator activity than control plasma. This finding, and the fact that adipose tissue lipoprotein lipase activity of fatties was about 150% of controls, suggests that fatties have increased capacities for VLDL catabolism. We have previously shown that hepatic VLDL secretory rates are higher than normal in these animals. The increased capacity for catabolism may be a response to the altered secretory rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369852"}
{"pmid": "4369853", "title": "Characterization of the rat apolipoproteins. I. The low molecular weight proteins of rat plasma high density lipoproteins.", "content": "Characterization of the rat apolipoproteins. I. The low molecular weight proteins of rat plasma high density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369853"}
{"pmid": "4369854", "title": "Characterization of vesicular stomatitis virus nucleocapsids. I. Complementary 40 S RNA molecules in nucleocapsids.", "content": "Characterization of vesicular stomatitis virus nucleocapsids. I. Complementary 40 S RNA molecules in nucleocapsids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369854"}
{"pmid": "4369855", "title": "Chemical and physiological approaches to neuroendocrine mechanisms: attempts at integration.", "content": "Chemical and physiological approaches to neuroendocrine mechanisms: attempts at integration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369855"}
{"pmid": "4369856", "title": "Chemical constituents of the digestive gland of the sea hare Aplysia californica. I. Importance of diet.", "content": "Chemical constituents of the digestive gland of the sea hare Aplysia californica. I. Importance of diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369856"}
{"pmid": "4369857", "title": "Chemical evolution. XXII. The hydantoins released on hydrolysis of HCN oligomers.", "content": "Chemical evolution. XXII. The hydantoins released on hydrolysis of HCN oligomers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369857"}
{"pmid": "4369859", "title": "Chemistry of the hypothalamic releasing factors--studies on structure-function relationships.", "content": "Chemistry of the hypothalamic releasing factors--studies on structure-function relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369859"}
{"pmid": "4369858", "title": "Chemistry and biological activity of vitamin D, its metabolites and analogs.", "content": "Chemistry and biological activity of vitamin D, its metabolites and analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369858"}
{"pmid": "4369861", "title": "Cholera enterotoxin stimulation of cAMP in cultured adrenal tumor cells.", "content": "Cholera enterotoxin stimulation of cAMP in cultured adrenal tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369861"}
{"pmid": "4369862", "title": "Cholesterol metabolism in the Ehrlich ascites tumor.", "content": "Cholesterol metabolism in the Ehrlich ascites tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369862"}
{"pmid": "4369863", "title": "Chromatin interaction with oestradiol-receptor protein complex.", "content": "Chromatin interaction with oestradiol-receptor protein complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369863"}
{"pmid": "4369864", "title": "Chromophobe adenoma masquerading as corticosteroid-responsive optic neuritis.", "content": "Chromophobe adenoma masquerading as corticosteroid-responsive optic neuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369864"}
{"pmid": "4369865", "title": "Clearing factor lipase and its role in the regulation of triglyceride utilization. Studies on the enzyme in adipose tissue.", "content": "Clearing factor lipase and its role in the regulation of triglyceride utilization. Studies on the enzyme in adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369865"}
{"pmid": "4369860", "title": "Chlorophyll a and cytochrome c at a heptane-water interface.", "content": "Chlorophyll a and cytochrome c at a heptane-water interface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369860"}
{"pmid": "4369866", "title": "Clofibrate reversal of platelet hypersensitivity in hyperbetalipoproteinemia.", "content": "Clofibrate reversal of platelet hypersensitivity in hyperbetalipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369866"}
{"pmid": "4369867", "title": "Closed circular DNAs with tandem repeats of a sequence from polyoma virus.", "content": "Closed circular DNAs with tandem repeats of a sequence from polyoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369867"}
{"pmid": "4369868", "title": "Clostridial myonecrosis of the abdominal wall. Management after extensive resection.", "content": "Clostridial myonecrosis of the abdominal wall. Management after extensive resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369868"}
{"pmid": "4369869", "title": "Clostridium perfringens type C in hemorrhagic enterotoxemia of neonatal calves in Alberta.", "content": "Clostridium perfringens type C in hemorrhagic enterotoxemia of neonatal calves in Alberta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369869"}
{"pmid": "4369870", "title": "Clostridium perfringens type D epsilon prototoxin. Some chemical, immunological and biological properties of a highly purified prototoxin.", "content": "Clostridium perfringens type D epsilon prototoxin. Some chemical, immunological and biological properties of a highly purified prototoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369870"}
{"pmid": "4369872", "title": "Collagen synthesis by lathyrogen-treated 3T6 fibroblasts.", "content": "Collagen synthesis by lathyrogen-treated 3T6 fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369872"}
{"pmid": "4369871", "title": "Collagen degradation in cultured keloid and hypertrophic scar tissue.", "content": "Collagen degradation in cultured keloid and hypertrophic scar tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369871"}
{"pmid": "4369873", "title": "Collagenase induced changes in the circular dichroism spectrum of collagen.", "content": "Collagenase induced changes in the circular dichroism spectrum of collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369873"}
{"pmid": "4369874", "title": "Color-enhanced chest roentgenography: a feasibility report.", "content": "Color-enhanced chest roentgenography: a feasibility report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369874"}
{"pmid": "4369875", "title": "Committee on Environmental Hazards. Noise pollution: neonatal aspects.", "content": "Committee on Environmental Hazards. Noise pollution: neonatal aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369875"}
{"pmid": "4369877", "title": "Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in rats.", "content": "Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369877"}
{"pmid": "4369876", "title": "Comparative sensitivity and resistance of some strains of Pseudomonas aeruginosa and Pseudomonas stutzeri to antibacterial agents.", "content": "Comparative sensitivity and resistance of some strains of Pseudomonas aeruginosa and Pseudomonas stutzeri to antibacterial agents. A comparison has been made of the sensitivities to various antibiotic and non-antibiotic substances of some strains of Pseudomonas aeruginosa and P. stutzeri, the latter including strains isolated from eye and other cosmetic products and from other sources. Whereas P. aeruginosa strains showed a high resistance to cetrimide and to benzalkonium chloride, the P. stutzeri strains were generally more sensitive to these and to chlorhexidine. The P. stutzeri strains were also more sensitive to the various antibiotics tested. The loss of the ability to transfer an R factor by two strains of P. aeruginosa caused no significant change in their drug sensitivity pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369876"}
{"pmid": "4369879", "title": "Comparison of effects of locally infused angiotensin I and II on hand veins and forearm arteries in man: evidence for converting enzyme activity in limb vessels.", "content": "Comparison of effects of locally infused angiotensin I and II on hand veins and forearm arteries in man: evidence for converting enzyme activity in limb vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369879"}
{"pmid": "4369880", "title": "Comparison of glucocorticoid cytoplasmic receptors from liver, Zajdela hepatoma and HTC cells.", "content": "Comparison of glucocorticoid cytoplasmic receptors from liver, Zajdela hepatoma and HTC cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369880"}
{"pmid": "4369881", "title": "Comparisons between induced by water deprivation or chemical stimulation.", "content": "Comparisons between induced by water deprivation or chemical stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369881"}
{"pmid": "4369883", "title": "Computerized tomography of the brain.", "content": "Computerized tomography of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369883"}
{"pmid": "4369882", "title": "Competitive binding assay for estradiol receptor using immobilized antibody.", "content": "Competitive binding assay for estradiol receptor using immobilized antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369882"}
{"pmid": "4369884", "title": "Conditions influencing inhibitors of the colony-stimulating factor (CSF).", "content": "Conditions influencing inhibitors of the colony-stimulating factor (CSF).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369884"}
{"pmid": "4369885", "title": "Conductometric evaluation of interactions of electrolytes with D-glucitol, D-glucose, glycerol, D-mannitol, and sucrose.", "content": "Conductometric evaluation of interactions of electrolytes with D-glucitol, D-glucose, glycerol, D-mannitol, and sucrose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369885"}
{"pmid": "4369886", "title": "Congenital goiter due to maternal ingestion of iodide.", "content": "Congenital goiter due to maternal ingestion of iodide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369886"}
{"pmid": "4369887", "title": "Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas.", "content": "Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas. Three exceptional cell lines have been tested for the presence of the Epstein-Barr virus genome by nucleic acid hybridization (complementary RNA.DNA) and Epstein-Barr virus-determined nuclear antigen tests. Two lines were derived from Swedish lymphoma cases and one from an African Burkitt-like lymphoma biopsy that was negative for Epstein-Barr virus DNA and the virus-determined nuclear antigen. All three lines apparently lacked the viral genome. Two of the three lines clearly had characteristics of B-cells (bone-marrow-derived).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369887"}
{"pmid": "4369889", "title": "Cooperative interactions between native and modified subunits of rabbit liver fructose 1,6-bisphosphatase.", "content": "Cooperative interactions between native and modified subunits of rabbit liver fructose 1,6-bisphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369889"}
{"pmid": "4369890", "title": "Correlation of (Na+--K+)-ATPase activity with growth of normal and transformed cells.", "content": "Correlation of (Na+--K+)-ATPase activity with growth of normal and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369890"}
{"pmid": "4369888", "title": "Control of uracil transport by cyclic AMP in E. coli.", "content": "Control of uracil transport by cyclic AMP in E. coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369888"}
{"pmid": "4369891", "title": "Correlation of pretreatment serum nonprotein-bound cortisol and total 17-hydroxycorticosteroid values with survival in patients with prostatic cancer.", "content": "Correlation of pretreatment serum nonprotein-bound cortisol and total 17-hydroxycorticosteroid values with survival in patients with prostatic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369891"}
{"pmid": "4369892", "title": "Corticosteroid therapy. Updating of principles.", "content": "Corticosteroid therapy. Updating of principles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369892"}
{"pmid": "4369893", "title": "Current problems in myocardial metabolism.", "content": "Current problems in myocardial metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369893"}
{"pmid": "4369878", "title": "Comparative study of several hypolipidemic agents related to clofibrate.", "content": "Comparative study of several hypolipidemic agents related to clofibrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369878"}
{"pmid": "4369894", "title": "Cushing's disease. Treatment by pituitary implantation of radioactive gold or yttrium seeds.", "content": "Cushing's disease. Treatment by pituitary implantation of radioactive gold or yttrium seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369894"}
{"pmid": "4369895", "title": "Cyclic changes in oviductal morphology and residual cytoplasmic estradiol binding capacity induced by sequential estradiol--progesterone treatment of spayed Rhesus monkeys.", "content": "Cyclic changes in oviductal morphology and residual cytoplasmic estradiol binding capacity induced by sequential estradiol--progesterone treatment of spayed Rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369895"}
{"pmid": "4369896", "title": "Cyclic guanosine monophosphate: elevation in degenerating photoreceptor cells of the C3H mouse retina.", "content": "Cyclic guanosine monophosphate: elevation in degenerating photoreceptor cells of the C3H mouse retina. As a result of an early deficiency in cyclic nucleotide phosphodiesterase activity, guanosine 3',5'-monophosphate accumulates in retinal photoreceptor cells before they begin to degenerate. It is suggested that degeneration of the photoreceptor cells is related to an imbalance in their metabolism or function which is caused by the elevated levels of cyclic guanosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369896"}
{"pmid": "4369897", "title": "Cyclic AMP as a cell surface activating agent in Dictyostelium discoideum.", "content": "Cyclic AMP as a cell surface activating agent in Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369897"}
{"pmid": "4369898", "title": "Cyclic AMP regulates phosphorylation of three protein components of rat cerebral cortex membranes for thirty minutes.", "content": "Cyclic AMP regulates phosphorylation of three protein components of rat cerebral cortex membranes for thirty minutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369898"}
{"pmid": "4369899", "title": "Cytidine 3',5'-monophosphate (cyclic CMP). II. Initiation of leukemia L-1210 cell growth in vitro.", "content": "Cytidine 3',5'-monophosphate (cyclic CMP). II. Initiation of leukemia L-1210 cell growth in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369899"}
{"pmid": "4369900", "title": "Cytogenetic study of primary tumors of chemical and viral origin in the golden hamster. Communication I. Karyotypic characteristics of tumors induced by the Rous sarcoma virus and by 7,12-dimethylbenzanthracene.", "content": "Cytogenetic study of primary tumors of chemical and viral origin in the golden hamster. Communication I. Karyotypic characteristics of tumors induced by the Rous sarcoma virus and by 7,12-dimethylbenzanthracene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369900"}
{"pmid": "4369902", "title": "Cytosol androgen receptor from kidney of normal and testicular feminized (Tfm) mice.", "content": "Cytosol androgen receptor from kidney of normal and testicular feminized (Tfm) mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369902"}
{"pmid": "4369901", "title": "Cytomegalovirus: Clinical virological correlations in renal transplant recipients.", "content": "Cytomegalovirus: Clinical virological correlations in renal transplant recipients. One-hundred thirty-two renal transplant recipients were systematically screened for viral infections and the findings correlated with the clinical course. One-hundred ten patients showed evidence of infection with herpesviruses and 89 patients showed laboratory evidence of infection with cytomegalovirus (CMV) uncomplicated by bacterial infections or technical complications. Patients without viral infections were usually asymptomatic. After recovery and development of anti-viral antibodies, most patients were asymptomatic despite the persistence of viral excretion in the urine. In contrast, the onset of viral infections were almost always accompanied by a significant clinical illness characterized by fever, leukopenia, and renal malfunction. Of 89 patients with cytomegalovirus infections, 83 survived at least three months. In these patients, the fever appeared to be self-limited and resolution of the fever was accompanied by increases in anti-CMV antibody. Renal biopsies demonstrated typical rejection reactions in all the biopsied patients and renal malfunction usually responded to anti-rejection treatment. Six of the 89 patients with CMV infections died within a month of viral isolation. These patients could be distinguished from those who recovered by a decreased or absent antibody response to the virus, suppressed lymphocyte responses to mitogen in autochthonous blood, and absent histologic evidence of rejection in the renal allografts. Thus, two paradoxical responses to CMV infections are seen in transplant patients: In the relatively immunocompetent patient, the infection is associated with renal allograft rejection, a prompt antibody response to the virus, and recovery. The severely immunosuppressed patient cannot make an antibody response, does not exhibit allograft rejection as a cause of renal malfunction, he may be further immunosuppressed by the viral infection, and is susceptible to sequential opportunistic infections leading to death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369901"}
{"pmid": "4369903", "title": "Daily changes in concentration of pancreatic and serum insulin and of blood glucose during 5 days of treatment of rats with growth hormone, ACTH, cortisol, dexamethasone, and tolbutamide alone and in combinations.", "content": "Daily changes in concentration of pancreatic and serum insulin and of blood glucose during 5 days of treatment of rats with growth hormone, ACTH, cortisol, dexamethasone, and tolbutamide alone and in combinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369903"}
{"pmid": "4369904", "title": "Daily rhythms of steroid and associated pituitary hormones in man and their relationship to sleep.", "content": "Daily rhythms of steroid and associated pituitary hormones in man and their relationship to sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369904"}
{"pmid": "4369905", "title": "Day care for cancer patients.", "content": "Day care for cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369905"}
{"pmid": "4369906", "title": "Degradation of O-phosphohydroxylysine in rat liver. Purification and properties of 2-aminoadipic semialdehyde dehydrogenase.", "content": "Degradation of O-phosphohydroxylysine in rat liver. Purification and properties of 2-aminoadipic semialdehyde dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369906"}
{"pmid": "4369907", "title": "Demonstration of two immunologically distinct xenotropic type C RNA viruses of mouse cells.", "content": "Demonstration of two immunologically distinct xenotropic type C RNA viruses of mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369907"}
{"pmid": "4369908", "title": "Deoxycholate-mediated cleavage of the protein of Sendai virus nucleocapsid derived from infected cells.", "content": "Deoxycholate-mediated cleavage of the protein of Sendai virus nucleocapsid derived from infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369908"}
{"pmid": "4369911", "title": "Detection of tricuspid valve vegetations by echocardiography.", "content": "Detection of tricuspid valve vegetations by echocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369911"}
{"pmid": "4369910", "title": "Depression of viral interferon induction in cell monolayers by coal dust.", "content": "Depression of viral interferon induction in cell monolayers by coal dust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369910"}
{"pmid": "4369912", "title": "Determinants and modification of adrenergic and vascular resistance in the kidney.", "content": "Determinants and modification of adrenergic and vascular resistance in the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369912"}
{"pmid": "4369913", "title": "Determination of leptophos, leptophos oxon, and a possible phenolic photoconversion metabolite in rapeseed grain.", "content": "Determination of leptophos, leptophos oxon, and a possible phenolic photoconversion metabolite in rapeseed grain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369913"}
{"pmid": "4369914", "title": "Development of hCG sensitivity in the testis of the immature rat.", "content": "Development of hCG sensitivity in the testis of the immature rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369914"}
{"pmid": "4369915", "title": "Dialysis schedule and peripheral neuropathy.", "content": "Dialysis schedule and peripheral neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369915"}
{"pmid": "4369916", "title": "Diazoxide, encorton and streptozotocin in the treatment of malignant betacytoma.", "content": "Diazoxide, encorton and streptozotocin in the treatment of malignant betacytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369916"}
{"pmid": "4369917", "title": "Dibutyryl cyclic AMP and cytotoxic lymphocytes in Hashimoto's thyroiditis.", "content": "Dibutyryl cyclic AMP and cytotoxic lymphocytes in Hashimoto's thyroiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369917"}
{"pmid": "4369918", "title": "Dietary modulation of beta cell adenylate cyclase activity.", "content": "Dietary modulation of beta cell adenylate cyclase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369918"}
{"pmid": "4369909", "title": "Depression in infant monkeys: physiological correlates.", "content": "Depression in infant monkeys: physiological correlates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369909"}
{"pmid": "4369919", "title": "Differences between liver and hepatoma cells in their complements of adenosine 3':5'-monophosphate-binding proteins and protein kinases.", "content": "Differences between liver and hepatoma cells in their complements of adenosine 3':5'-monophosphate-binding proteins and protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369919"}
{"pmid": "4369920", "title": "Differences between the integration of avian myeloblastosis virus DNA in leukemic cells and of endogenous viral DNA in normal chicken cells.", "content": "Differences between the integration of avian myeloblastosis virus DNA in leukemic cells and of endogenous viral DNA in normal chicken cells. The nature of integrated viral DNA in normal and leukemic chicken cells has been studied by sequential nucleic acid hybridization procedures that localize the viral specific DNA in cellular DNA regions differing in reiteration frequency. First, DNA.DNA reassociation was employed to fractionate cellular DNA sequences according to their reiteration frequencies. Next, the DNA in each fraction was denatured, immobilized on nitrocellulose filters, and then hybridized with viral [(3)H]RNA. In normal cells, endogenous viral DNA appears to be associated with cell sequences reiterated 1200 times, and each integration unit appears to have a maximal size approximately equivalent to the 35S RNA subunit of the virion. In infected cells, additional viral sequences are found which reassociate as if they integrated adjacent to unique cellular DNA, or in tandem with endogenous viral DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369920"}
{"pmid": "4369922", "title": "Different sensitivity of nuclear and microsomal NADH-cytochrome c reductase activities to thenoyltrifluoroacetone.", "content": "Different sensitivity of nuclear and microsomal NADH-cytochrome c reductase activities to thenoyltrifluoroacetone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369922"}
{"pmid": "4369921", "title": "Different effects of hormonal peptides and cyclic adenosine 3',5'-monophosphate on colonic transport in vitro.", "content": "Different effects of hormonal peptides and cyclic adenosine 3',5'-monophosphate on colonic transport in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369921"}
{"pmid": "4369924", "title": "Diffusion and convection in normal and neoplastic tissues.", "content": "Diffusion and convection in normal and neoplastic tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369924"}
{"pmid": "4369923", "title": "Differential effects of an angiotensin II analogue on pressor and adrenal receptors in the rabbit.", "content": "Differential effects of an angiotensin II analogue on pressor and adrenal receptors in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369923"}
{"pmid": "4369926", "title": "Direct involvement of vitamin D in the regulation of 25-hydroxycholecalciferol metabolism.", "content": "Direct involvement of vitamin D in the regulation of 25-hydroxycholecalciferol metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369926"}
{"pmid": "4369927", "title": "Discharge planning: tentative program improves utilization.", "content": "Discharge planning: tentative program improves utilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369927"}
{"pmid": "4369925", "title": "Dilution kinetic studies of yeast populations: in vivo aggregation of galactose utilizing enzymes and positive regulator molecules.", "content": "Dilution kinetic studies of yeast populations: in vivo aggregation of galactose utilizing enzymes and positive regulator molecules. By use of a selective medium containing ethidium bromide, population analyses of yeast galactose long-term adaptation mutants (gal3) in the process of deadaptation in the absence of galactose have been performed. The analysis of diploid strains homozygous for the gal3 locus but heterozygous for different combinations of the other mutant galactose loci, which thus have reduced amounts of the gene products of those loci, have demonstrated that, in addition to the two permease units determined in a previous study, a cell requires one complex of the Leloir pathway enzymes and two complexes specified by the Gal4 locus to be readily induced. From the consideration of these complexes as being aggregated molecules which are diluted out as units (i.e., if such a molecule were a dimer, it would not dissociate into monomers) during cell growth, the in vivo aggregation of these enzymes and the Gal4 gene product could be studied. The data indicate that the function of the Gal4 gene product is to activate a Leloir enzyme complex. It is postulated that the gal3 phenotype is the result of such strains' inability to actively synthesize an endogenous co-inducer which allows wild-type cells to be readily induced upon exposure to galactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369925"}
{"pmid": "4369928", "title": "Dispersion and isolation of beating cells from adult rat heart.", "content": "Dispersion and isolation of beating cells from adult rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369928"}
{"pmid": "4369929", "title": "Distinct molecular species of interferons.", "content": "Distinct molecular species of interferons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369929"}
{"pmid": "4369930", "title": "Distribution patterns of hepatitis B antigen in the liver. Immunofluorescence studies.", "content": "Distribution patterns of hepatitis B antigen in the liver. Immunofluorescence studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369930"}
{"pmid": "4369931", "title": "Distrubances in tryptophan metabolism after a single dose of aflatoxin B1 and chronic intoxication with carbon tetrachloride.", "content": "Distrubances in tryptophan metabolism after a single dose of aflatoxin B1 and chronic intoxication with carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369931"}
{"pmid": "4369932", "title": "Dominant lethal mutations induced in mice by orally administered ethyl methanesulfonate.", "content": "Dominant lethal mutations induced in mice by orally administered ethyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369932"}
{"pmid": "4369934", "title": "Dosimetry of the SIN biomedical pion beam with tissue-equivalent ionization chambers.", "content": "Dosimetry of the SIN biomedical pion beam with tissue-equivalent ionization chambers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369934"}
{"pmid": "4369933", "title": "Dopaminergic inhibition of striatal cholinergic neurons: synergistic blocking action of gamma-butyrolactone and neuroleptic drugs.", "content": "Dopaminergic inhibition of striatal cholinergic neurons: synergistic blocking action of gamma-butyrolactone and neuroleptic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369933"}
{"pmid": "4369935", "title": "Dosimetry studies on the ethylation of mouse sperm DNA after in vivo exposure to (3H)ethyl metanesulfonate.", "content": "Dosimetry studies on the ethylation of mouse sperm DNA after in vivo exposure to (3H)ethyl metanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369935"}
{"pmid": "4369937", "title": "DNA strand breakage caused by dichlorvos, methyl methanesulphonate and iodoacetamide in Escherichia coli and cultured Chinese hamster cells.", "content": "DNA strand breakage caused by dichlorvos, methyl methanesulphonate and iodoacetamide in Escherichia coli and cultured Chinese hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369937"}
{"pmid": "4369936", "title": "Dynamics of functional and ultrastructural changes in the liver cells during the development of allyl alcohol necrosis.", "content": "Dynamics of functional and ultrastructural changes in the liver cells during the development of allyl alcohol necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369936"}
{"pmid": "4369939", "title": "Early and late averaged electroencephalic responses at low sensation levels.", "content": "Early and late averaged electroencephalic responses at low sensation levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369939"}
{"pmid": "4369938", "title": "DNA strand scission by the antitumor protein neocarzinostatin.", "content": "DNA strand scission by the antitumor protein neocarzinostatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369938"}
{"pmid": "4369940", "title": "Early and late viral-specific polyribosomal RNA in herpes virus-1 and -2-infected rabbit kidney cells.", "content": "Early and late viral-specific polyribosomal RNA in herpes virus-1 and -2-infected rabbit kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369940"}
{"pmid": "4369941", "title": "Early components of the averaged electroencephalic response to monaural and binaural stimulation.", "content": "Early components of the averaged electroencephalic response to monaural and binaural stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369941"}
{"pmid": "4369942", "title": "Early diagnosis of carcinoma of the bronchi with special reference to catheter biopsy.", "content": "Early diagnosis of carcinoma of the bronchi with special reference to catheter biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369942"}
{"pmid": "4369943", "title": "Early tendon transfer in upper extremity peripheral nerve injury.", "content": "Early tendon transfer in upper extremity peripheral nerve injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369943"}
{"pmid": "4369944", "title": "Editorial: Acute hemorrhagic conjunctivitis.", "content": "Editorial: Acute hemorrhagic conjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369944"}
{"pmid": "4369945", "title": "Editorial: Hepatitis and herpesvirus.", "content": "Editorial: Hepatitis and herpesvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369945"}
{"pmid": "4369946", "title": "Editorial: Neuroblastoma: possible viral aetiology?", "content": "Editorial: Neuroblastoma: possible viral aetiology?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369946"}
{"pmid": "4369948", "title": "Editorial: Vaccination against whooping cough.", "content": "Editorial: Vaccination against whooping cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369948"}
{"pmid": "4369947", "title": "Editorial: The national Wilms tumor study. A progress report.", "content": "Editorial: The national Wilms tumor study. A progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369947"}
{"pmid": "4369949", "title": "Effect of \"Aquasol A\", vitamin A, and \"Tween 80\" on vesicular stomatitis virus plaque formation and on interferon action.", "content": "Effect of \"Aquasol A\", vitamin A, and \"Tween 80\" on vesicular stomatitis virus plaque formation and on interferon action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369949"}
{"pmid": "4369950", "title": "Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin.", "content": "Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369950"}
{"pmid": "4369951", "title": "Effect of cytochalasin B on hexose transport and glucose metabolism in pancreatic islets.", "content": "Effect of cytochalasin B on hexose transport and glucose metabolism in pancreatic islets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369951"}
{"pmid": "4369952", "title": "Effect of energy-rich compounds on release of intracellular enzymes from human leukocytes and rat lymphocytes.", "content": "Effect of energy-rich compounds on release of intracellular enzymes from human leukocytes and rat lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369952"}
{"pmid": "4369954", "title": "Effect of glucagon, dibutyryl adenosine 3',5'-cyclic monophosphate and phosphodiesterase inhibitors on rat liver phosphorylase activity and adenosine 3',5'-cyclic monophosphate levels.", "content": "Effect of glucagon, dibutyryl adenosine 3',5'-cyclic monophosphate and phosphodiesterase inhibitors on rat liver phosphorylase activity and adenosine 3',5'-cyclic monophosphate levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369954"}
{"pmid": "4369953", "title": "Effect of flurazepam on sleep in the laboratory.", "content": "Effect of flurazepam on sleep in the laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369953"}
{"pmid": "4369956", "title": "Effect of morphine on serotonin release from myenteric plexus of the guinea pig.", "content": "Effect of morphine on serotonin release from myenteric plexus of the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369956"}
{"pmid": "4369957", "title": "Effect of plasma protein concentration on glomerular and tubular function.", "content": "Effect of plasma protein concentration on glomerular and tubular function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369957"}
{"pmid": "4369959", "title": "Effect of prostaglandins on the velocity of the reaction between human renin and homologous renin substrate.", "content": "Effect of prostaglandins on the velocity of the reaction between human renin and homologous renin substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369959"}
{"pmid": "4369960", "title": "Effect of subacute administration of human growth hormone on various serum lipid and hormone levels of hypercholesterolemic and normocholesterolemic subjects.", "content": "Effect of subacute administration of human growth hormone on various serum lipid and hormone levels of hypercholesterolemic and normocholesterolemic subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369960"}
{"pmid": "4369961", "title": "Effect of testes removal and androgen replacement therapy on enzyme levels in hypothalamus and pituitary of frog (Rana esculenta).", "content": "Effect of testes removal and androgen replacement therapy on enzyme levels in hypothalamus and pituitary of frog (Rana esculenta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369961"}
{"pmid": "4369962", "title": "Effect of tissue injury on tumorigenesis induced by murine sarcoma virus (Harvey).", "content": "Effect of tissue injury on tumorigenesis induced by murine sarcoma virus (Harvey).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369962"}
{"pmid": "4369964", "title": "Effect of 1,10-phenanthroline and desferrioxamine in vivo on prolyl hydroxylase and hydroxylation of collagen in various tissues of rats.", "content": "Effect of 1,10-phenanthroline and desferrioxamine in vivo on prolyl hydroxylase and hydroxylation of collagen in various tissues of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369964"}
{"pmid": "4369963", "title": "Effect of IUD on uterine cyclic AMP and the activities of adenyl cyclase and phosphodiesterase during the oestrous cycle and early pregnancy in rats.", "content": "Effect of IUD on uterine cyclic AMP and the activities of adenyl cyclase and phosphodiesterase during the oestrous cycle and early pregnancy in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369963"}
{"pmid": "4369965", "title": "Effects of acetylimidazole on the hydrolysis of fructose diphosphate and p-nitrophenyl phosphate by liver fructose diphosphatase.", "content": "Effects of acetylimidazole on the hydrolysis of fructose diphosphate and p-nitrophenyl phosphate by liver fructose diphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369965"}
{"pmid": "4369966", "title": "Effects of dimethylsulfoxide on the E. coli gal operon and on bacteriophage lambda in vivo.", "content": "Effects of dimethylsulfoxide on the E. coli gal operon and on bacteriophage lambda in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369966"}
{"pmid": "4369967", "title": "Effects of drugs on the metabolism of bile acids.", "content": "Effects of drugs on the metabolism of bile acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369967"}
{"pmid": "4369969", "title": "Effects of growth phase and repair capacity on rejoining of ethyl methanesulfonate-induced DNA breaks in Escherichia coli.", "content": "Effects of growth phase and repair capacity on rejoining of ethyl methanesulfonate-induced DNA breaks in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369969"}
{"pmid": "4369968", "title": "Effects of factors influencing the activity of the reticuloendothelial system on the half-life of labelled beta-lipoproteins. Preliminary report.", "content": "Effects of factors influencing the activity of the reticuloendothelial system on the half-life of labelled beta-lipoproteins. Preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369968"}
{"pmid": "4369971", "title": "Effects of pokeweed mitogen, cholera toxin and prostaglandin E1 on immunoglobulin production and cyclic AMP levels in tonsillar lymphocytes.", "content": "Effects of pokeweed mitogen, cholera toxin and prostaglandin E1 on immunoglobulin production and cyclic AMP levels in tonsillar lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369971"}
{"pmid": "4369970", "title": "Effects of pituitary hormones and corticosterone on lipolysis in hypophysectomized rats.", "content": "Effects of pituitary hormones and corticosterone on lipolysis in hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369970"}
{"pmid": "4369972", "title": "Effects of prostaglandin E1 and isoproterenol on cyclic AMP content of human fibroblasts modified by time and cell density in subculture.", "content": "Effects of prostaglandin E1 and isoproterenol on cyclic AMP content of human fibroblasts modified by time and cell density in subculture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369972"}
{"pmid": "4369955", "title": "Effect of imipramine on adrenergic responses.", "content": "Effect of imipramine on adrenergic responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369955"}
{"pmid": "4369973", "title": "Effects of prostaglandins, cyclic AMP, seminal plasma, indomethacin, and other factors on oviposition in the Japanese quail, Coturnix coturnix japonica.", "content": "Effects of prostaglandins, cyclic AMP, seminal plasma, indomethacin, and other factors on oviposition in the Japanese quail, Coturnix coturnix japonica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369973"}
{"pmid": "4369974", "title": "Effects of tetrahydrocannabinols on cyclic AMP levels in rat brain areas.", "content": "Effects of tetrahydrocannabinols on cyclic AMP levels in rat brain areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369974"}
{"pmid": "4369976", "title": "Effects of the 3',5'-cyclic phosphates of 2-methylthioadenosine, 2-chloroadenosine and adenosine on platelet aggregation.", "content": "Effects of the 3',5'-cyclic phosphates of 2-methylthioadenosine, 2-chloroadenosine and adenosine on platelet aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369976"}
{"pmid": "4369958", "title": "Effect of propranolol on pituitary adrenal axis.", "content": "Effect of propranolol on pituitary adrenal axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369958"}
{"pmid": "4369978", "title": "Elastosis in tubular carcinoma of the breast.", "content": "Elastosis in tubular carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369978"}
{"pmid": "4369977", "title": "Effects of vitamin D3 on duodenal absorptive cells of chicks. An electron microscopic study.", "content": "Effects of vitamin D3 on duodenal absorptive cells of chicks. An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369977"}
{"pmid": "4369979", "title": "Electromyography and nerve conduction measurements.", "content": "Electromyography and nerve conduction measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369979"}
{"pmid": "4369981", "title": "Electron microscopy of the pulmonary alveolar cells (granular pneumocytes) of normal and vagotomized amphibian (Bufo icterus icterus).", "content": "Electron microscopy of the pulmonary alveolar cells (granular pneumocytes) of normal and vagotomized amphibian (Bufo icterus icterus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369981"}
{"pmid": "4369975", "title": "Effects of the combination of nicotinic acid and propranolol in very low doses on blood lipids in man.", "content": "Effects of the combination of nicotinic acid and propranolol in very low doses on blood lipids in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369975"}
{"pmid": "4369982", "title": "Electron paramagnetic resonance of single crystal 15N-nitrosyl-57Fe-myoglobin.", "content": "Electron paramagnetic resonance of single crystal 15N-nitrosyl-57Fe-myoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369982"}
{"pmid": "4369983", "title": "Electron paramagnetic resonance studies of the structure and metal ion exchange kinetics of vanadyl(IV) bovine carbonic anhydrase.", "content": "Electron paramagnetic resonance studies of the structure and metal ion exchange kinetics of vanadyl(IV) bovine carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369983"}
{"pmid": "4369984", "title": "Electrophoretic characterization of shuttling and nonshuttling small nuclear RNAs.", "content": "Electrophoretic characterization of shuttling and nonshuttling small nuclear RNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369984"}
{"pmid": "4369985", "title": "Elevation of renal cyclic GMP concentrations and plasma lysosomal enzyme activity following cobalt treatment in rats.", "content": "Elevation of renal cyclic GMP concentrations and plasma lysosomal enzyme activity following cobalt treatment in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369985"}
{"pmid": "4369986", "title": "Elucidation of the exact sites of cleavage of tropocollagen by rheumatoid synovial collagenase: correlation of cleavage sites with fibril structure.", "content": "Elucidation of the exact sites of cleavage of tropocollagen by rheumatoid synovial collagenase: correlation of cleavage sites with fibril structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369986"}
{"pmid": "4369987", "title": "Embryonic differentiation in the nucleoside triphosphatase activities of myosin from the fast, slow and cardiac muscles of chick.", "content": "Embryonic differentiation in the nucleoside triphosphatase activities of myosin from the fast, slow and cardiac muscles of chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369987"}
{"pmid": "4369980", "title": "Electron microscope studies of the antileprosy drug B663 (clofazimine; Lamprenel).", "content": "Electron microscope studies of the antileprosy drug B663 (clofazimine; Lamprenel).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369980"}
{"pmid": "4369988", "title": "Endocrine disorders as a contributory factor to neoplasia in SJL-J mice.", "content": "Endocrine disorders as a contributory factor to neoplasia in SJL-J mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369988"}
{"pmid": "4369989", "title": "Endocrine evaluation in thalassemia major.", "content": "Endocrine evaluation in thalassemia major.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369989"}
{"pmid": "4369990", "title": "Endocrine function in thalassemia major.", "content": "Endocrine function in thalassemia major.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369990"}
{"pmid": "4369991", "title": "Enhancement of Simian virus 40-induced transformation of Chinese hamster embryo cells by 4-nitroquinoline 1-oxide.", "content": "Enhancement of Simian virus 40-induced transformation of Chinese hamster embryo cells by 4-nitroquinoline 1-oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369991"}
{"pmid": "4369992", "title": "Envelope proteins of vesicular stomatitis virions: accessibility to iodination.", "content": "Envelope proteins of vesicular stomatitis virions: accessibility to iodination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369992"}
{"pmid": "4369993", "title": "Enzymatic activation of Clostridium perfringens epsilon prototoxin and some biological properties of activated toxin.", "content": "Enzymatic activation of Clostridium perfringens epsilon prototoxin and some biological properties of activated toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369993"}
{"pmid": "4369995", "title": "Epidemiology as a field of practice.", "content": "Epidemiology as a field of practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369995"}
{"pmid": "4369996", "title": "Episodic secretion of luteinizing hormone-releasing factor (LRF) in the human.", "content": "Episodic secretion of luteinizing hormone-releasing factor (LRF) in the human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369996"}
{"pmid": "4369994", "title": "Enzymatic synthesis of 2-keto-3-deoxy-d-glucose from D-gluconate.", "content": "Enzymatic synthesis of 2-keto-3-deoxy-d-glucose from D-gluconate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369994"}
{"pmid": "4369997", "title": "Erythema annulare centrifugum coincident with Epstein-Barr virus infection in an infant.", "content": "Erythema annulare centrifugum coincident with Epstein-Barr virus infection in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369997"}
{"pmid": "4369998", "title": "Erythrocyte phosphoribosylpyrophosphate concentrations in heterozygotes for hypoxanthine-guanine phosphoribosyltransferase deficiency.", "content": "Erythrocyte phosphoribosylpyrophosphate concentrations in heterozygotes for hypoxanthine-guanine phosphoribosyltransferase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369998"}
{"pmid": "4369999", "title": "Erythrocytic galactokinase activity in neonatal and adult blood from various mammalian species.", "content": "Erythrocytic galactokinase activity in neonatal and adult blood from various mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4369999"}
{"pmid": "4370000", "title": "Erythroleukemia in two infant chimpanzees fed milk from cows naturally infected with the bovine C-type virus.", "content": "Erythroleukemia in two infant chimpanzees fed milk from cows naturally infected with the bovine C-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370000"}
{"pmid": "4370001", "title": "Estradiol binding to rat corpora lutea during pregnancy.", "content": "Estradiol binding to rat corpora lutea during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370001"}
{"pmid": "4370002", "title": "Estrogen receptor in normal and neoplastic mouse mammary tissues.", "content": "Estrogen receptor in normal and neoplastic mouse mammary tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370002"}
{"pmid": "4370003", "title": "Estrogen receptor interaction with the antitumor agent estradiol mustard.", "content": "Estrogen receptor interaction with the antitumor agent estradiol mustard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370003"}
{"pmid": "4370004", "title": "Estrogen receptors: physiology and clinical applications.", "content": "Estrogen receptors: physiology and clinical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370004"}
{"pmid": "4370006", "title": "Evidence for a dual central role for angiotensin in water and sodium intake.", "content": "Evidence for a dual central role for angiotensin in water and sodium intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370006"}
{"pmid": "4370005", "title": "Estrogenic regulation of uterine cyclic AMP metabolism.", "content": "Estrogenic regulation of uterine cyclic AMP metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370005"}
{"pmid": "4370007", "title": "Evidence for a structural interaction between ATP synthetase and cytochrome c oxidase in mitochondria.", "content": "Evidence for a structural interaction between ATP synthetase and cytochrome c oxidase in mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370007"}
{"pmid": "4370008", "title": "Evidence for a subcellular vesicular site of collagen prolyl hydroxylation.", "content": "Evidence for a subcellular vesicular site of collagen prolyl hydroxylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370008"}
{"pmid": "4370009", "title": "Evidence for common nucleotide sequences in the RNA subunits comprising Rous sarcoma virus 70 S RNA.", "content": "Evidence for common nucleotide sequences in the RNA subunits comprising Rous sarcoma virus 70 S RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370009"}
{"pmid": "4370012", "title": "Evidence for the T cell specificity of sodium periodate-induced lymphocyte blastogenesis.", "content": "Evidence for the T cell specificity of sodium periodate-induced lymphocyte blastogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370012"}
{"pmid": "4370013", "title": "Evidence that adenosine 3', 5'-cyclic monophosphate is not involved in the growth response of prostate to androgens.", "content": "Evidence that adenosine 3', 5'-cyclic monophosphate is not involved in the growth response of prostate to androgens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370013"}
{"pmid": "4370011", "title": "Evidence for persistence of infectious agents in isolated human populations.", "content": "Evidence for persistence of infectious agents in isolated human populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370011"}
{"pmid": "4370014", "title": "Excretion of cyclic 3',5'-adenosine monophosphate in renal insufficiency and primary hyperparathyroidism after stimulation with parathyroid hormone.", "content": "Excretion of cyclic 3',5'-adenosine monophosphate in renal insufficiency and primary hyperparathyroidism after stimulation with parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370014"}
{"pmid": "4370015", "title": "Experiences in computer audiometry (ECoG and ERA).", "content": "Experiences in computer audiometry (ECoG and ERA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370015"}
{"pmid": "4370016", "title": "Experimental encephalomyocarditis virus infection of pigs.", "content": "Experimental encephalomyocarditis virus infection of pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370016"}
{"pmid": "4370017", "title": "Explants, transplants and implants of a cartilage and bone morphogenetic matrix.", "content": "Explants, transplants and implants of a cartilage and bone morphogenetic matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370017"}
{"pmid": "4370018", "title": "Extracellular current density analysis of responses in cerebellar cortex to mossy fiber activation.", "content": "Extracellular current density analysis of responses in cerebellar cortex to mossy fiber activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370018"}
{"pmid": "4370019", "title": "Fabry's disease in a black man without skin lesions.", "content": "Fabry's disease in a black man without skin lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370019"}
{"pmid": "4370020", "title": "Fatty acids composition of very low density lipoprotein in psoriatic serum.", "content": "Fatty acids composition of very low density lipoprotein in psoriatic serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370020"}
{"pmid": "4370021", "title": "Fibroma regression in relation to antibody and challenge immunity to bovine papilloma virus.", "content": "Fibroma regression in relation to antibody and challenge immunity to bovine papilloma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370021"}
{"pmid": "4370022", "title": "Fibrous histiocytoma of the corneoscleral limbus.", "content": "Fibrous histiocytoma of the corneoscleral limbus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370022"}
{"pmid": "4370024", "title": "Fine structure of rat carotid body after 6-methylprednisolone treatment.", "content": "Fine structure of rat carotid body after 6-methylprednisolone treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370024"}
{"pmid": "4370023", "title": "Filter assay for 1alpha, 25-dihydroxyvitamin D3. Utilization of the hormone's target tissue chromatin receptor.", "content": "Filter assay for 1alpha, 25-dihydroxyvitamin D3. Utilization of the hormone's target tissue chromatin receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370023"}
{"pmid": "4370010", "title": "Evidence for myocardial conversion of angiotensin I.", "content": "Evidence for myocardial conversion of angiotensin I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370010"}
{"pmid": "4370025", "title": "Flank tumours in infants and children.", "content": "Flank tumours in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370025"}
{"pmid": "4370027", "title": "Fluoride uptake from prophylactic dentifrices. IV. In vitro fluoride uptake from two different types of abrasive dentifrices.", "content": "Fluoride uptake from prophylactic dentifrices. IV. In vitro fluoride uptake from two different types of abrasive dentifrices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370027"}
{"pmid": "4370026", "title": "Flash photolysis--electron spin resonance studies of the dynamics of photosystem I. 3. Temperature dependence of the decay of signal I.", "content": "Flash photolysis--electron spin resonance studies of the dynamics of photosystem I. 3. Temperature dependence of the decay of signal I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370026"}
{"pmid": "4370028", "title": "Fractionation of plasma lipoproteins by density gradient centrifugation in swing-out rotors.", "content": "Fractionation of plasma lipoproteins by density gradient centrifugation in swing-out rotors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370028"}
{"pmid": "4370031", "title": "Functional classes of cells and their laminar distribution in monkey visual cortex.", "content": "Functional classes of cells and their laminar distribution in monkey visual cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370031"}
{"pmid": "4370029", "title": "Fructose-1,6-diphosphatase deficiency: another enzyme defect which can present itself with the clinical features of \"tyrosinosis\".", "content": "Fructose-1,6-diphosphatase deficiency: another enzyme defect which can present itself with the clinical features of \"tyrosinosis\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370029"}
{"pmid": "4370032", "title": "Functional organization of receptive fields in thalamic ventrobasal neurons examined by neuronal response to iterative electrical stimulation of skin.", "content": "Functional organization of receptive fields in thalamic ventrobasal neurons examined by neuronal response to iterative electrical stimulation of skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370032"}
{"pmid": "4370030", "title": "Functional arginyl residues as NADH binding sites of alcohol dehydrogenases.", "content": "Functional arginyl residues as NADH binding sites of alcohol dehydrogenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370030"}
{"pmid": "4370033", "title": "Further investigations of the expression of SV40-induced surface antigens subsequent to enzymatic treatment of transformed cells.", "content": "Further investigations of the expression of SV40-induced surface antigens subsequent to enzymatic treatment of transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370033"}
{"pmid": "4370034", "title": "Further studies of histone phosphorylation in the presence of inhibitors of DNA synthesis.", "content": "Further studies of histone phosphorylation in the presence of inhibitors of DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370034"}
{"pmid": "4370035", "title": "Further studies on the accumulation and binding of androgen in rat epididymis.", "content": "Further studies on the accumulation and binding of androgen in rat epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370035"}
{"pmid": "4370036", "title": "Further studies on the stimulation of prostatic ribonucleic acid polymerase by x-5 alpha-dihydrotestosterone-receptor complexes.", "content": "Further studies on the stimulation of prostatic ribonucleic acid polymerase by x-5 alpha-dihydrotestosterone-receptor complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370036"}
{"pmid": "4370037", "title": "Gangliosides of bovine optic nerve.", "content": "Gangliosides of bovine optic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370037"}
{"pmid": "4370038", "title": "Gas chromatographic estimation of hydroxyproline.", "content": "Gas chromatographic estimation of hydroxyproline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370038"}
{"pmid": "4370040", "title": "Gas-liquid chromatographic determination of vitamin D 2 in fortified full-cream dried milk.", "content": "Gas-liquid chromatographic determination of vitamin D 2 in fortified full-cream dried milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370040"}
{"pmid": "4370041", "title": "Gastric leiomyoblastoma.", "content": "Gastric leiomyoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370041"}
{"pmid": "4370042", "title": "General proteolytic activity of highly purified preparations of clostridial collagenase.", "content": "General proteolytic activity of highly purified preparations of clostridial collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370042"}
{"pmid": "4370045", "title": "Genetic study on susceptibility of different mouse lines to ectromelia virus.", "content": "Genetic study on susceptibility of different mouse lines to ectromelia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370045"}
{"pmid": "4370044", "title": "Genetic expression of aryl hydrocarbon hydroxylase activity. Induction of monooxygenase activities and cytochrome P1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically \"nonresponsive\" to other aromatic hydrocarbons.", "content": "Genetic expression of aryl hydrocarbon hydroxylase activity. Induction of monooxygenase activities and cytochrome P1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically \"nonresponsive\" to other aromatic hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370044"}
{"pmid": "4370039", "title": "Gas-chromatographic detection of isethionic acid in pig heart.", "content": "Gas-chromatographic detection of isethionic acid in pig heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370039"}
{"pmid": "4370046", "title": "Giant cell tumour associated with rheumatoid arthritis.", "content": "Giant cell tumour associated with rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370046"}
{"pmid": "4370047", "title": "Glomerular permeability to protein molecules--its possible structural basis.", "content": "Glomerular permeability to protein molecules--its possible structural basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370047"}
{"pmid": "4370048", "title": "Glomus tumour. A review of 15 clinical cases.", "content": "Glomus tumour. A review of 15 clinical cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370048"}
{"pmid": "4370043", "title": "Generalized planar xanthomata associated with multiple myeloma and hyperlipoproteinemia.", "content": "Generalized planar xanthomata associated with multiple myeloma and hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370043"}
{"pmid": "4370049", "title": "Glucocorticoid receptors. Characteristics, specificity, and ontogenesis in embryonic chick neural retina.", "content": "Glucocorticoid receptors. Characteristics, specificity, and ontogenesis in embryonic chick neural retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370049"}
{"pmid": "4370050", "title": "Glucocorticoid-binding components in an irradiation-induced thymoma of the C57BL-6J mouse.", "content": "Glucocorticoid-binding components in an irradiation-induced thymoma of the C57BL-6J mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370050"}
{"pmid": "4370051", "title": "Glycogen metabolism in macrophages: effect of exogenous glycogen on glucogenesis in inflammatory exudate leukocytes and macrophages.", "content": "Glycogen metabolism in macrophages: effect of exogenous glycogen on glucogenesis in inflammatory exudate leukocytes and macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370051"}
{"pmid": "4370052", "title": "Glycolytic enzymes in muscle of the pacific dolphin: role of pyruvate kinase in aerobic-anaerobic transition during diving.", "content": "Glycolytic enzymes in muscle of the pacific dolphin: role of pyruvate kinase in aerobic-anaerobic transition during diving.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370052"}
{"pmid": "4370053", "title": "Gonadal androgen and sociosexual behavior of male mammals: a comparative analysis.", "content": "Gonadal androgen and sociosexual behavior of male mammals: a comparative analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370053"}
{"pmid": "4370055", "title": "Granular cell myoblastoma lentiginosis profusa.", "content": "Granular cell myoblastoma lentiginosis profusa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370055"}
{"pmid": "4370054", "title": "Gram-negative bacteria isolated from external eye infections.", "content": "Gram-negative bacteria isolated from external eye infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370054"}
{"pmid": "4370056", "title": "Granular cell myoblastoma of the Larynx.", "content": "Granular cell myoblastoma of the Larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370056"}
{"pmid": "4370057", "title": "Granulated hydroxyapatite: preparation and chromatographic properties.", "content": "Granulated hydroxyapatite: preparation and chromatographic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370057"}
{"pmid": "4370058", "title": "Growth and body composition in intrauterine growth retardation (IUGR) before and during human growth hormone administration.", "content": "Growth and body composition in intrauterine growth retardation (IUGR) before and during human growth hormone administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370058"}
{"pmid": "4370059", "title": "Growth control in chick embryo fibroblasts; no evidence for a specific role for cyclic purine nucleotides.", "content": "Growth control in chick embryo fibroblasts; no evidence for a specific role for cyclic purine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370059"}
{"pmid": "4370060", "title": "Haem-haem interactions in cytochrome aa3 during the anaerobic-aerobic transition.", "content": "Haem-haem interactions in cytochrome aa3 during the anaerobic-aerobic transition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370060"}
{"pmid": "4370061", "title": "Hepatic artery ligation: adjunct in the management of massive hemorrhage from the liver.", "content": "Hepatic artery ligation: adjunct in the management of massive hemorrhage from the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370061"}
{"pmid": "4370062", "title": "Hepatocellular cacinoma; prolonged survival following resection.", "content": "Hepatocellular cacinoma; prolonged survival following resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370062"}
{"pmid": "4370063", "title": "Hepatocellular tolerance to carbon tetrachloride induced injury in the rat: a study of its nature and possible mode of evolution.", "content": "Hepatocellular tolerance to carbon tetrachloride induced injury in the rat: a study of its nature and possible mode of evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370063"}
{"pmid": "4370064", "title": "Herpes simplex-genitalis virus nonvirion antigens and their implication in certain human cancers: unconfirmed.", "content": "Herpes simplex-genitalis virus nonvirion antigens and their implication in certain human cancers: unconfirmed. The previously reported data on the existence of herpes simplex-genitalis virus nonvirion, neoantigens with distinctive properties, and on the presence of specific antibodies for these neoantigens only in the sera of specially hyperimmunized guinea pigs or of patients with certain types of cancer, could not be confirmed. Many factors that could have been responsible for the difference between the originally reported results and those recently obtained were carefully checked and investigated. The assumption that a mixture of two anticomplementary ingredients bound at least as much complement as the more anticomplementary component, and sometimes more, was found to be incorrect for the ingredients used in this work; the reverse was true. Previous failure to observe some of the strict requirements of the complement fixation test could account for some but not all of the unconfirmed previously reported data. Conclusions, based on the unconfirmed data, including those implicating these viruses in the etiology of certain human cancers, are therefore negated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370064"}
{"pmid": "4370065", "title": "Heterogeneity and unusually high affinity in the interactions of adenosine 3':5'-monophosphate with specific binding proteins from liver and hepatoma cells.", "content": "Heterogeneity and unusually high affinity in the interactions of adenosine 3':5'-monophosphate with specific binding proteins from liver and hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370065"}
{"pmid": "4370067", "title": "High-molecular-weight DNA associated with intracytoplasmic A-particle inclusions.", "content": "High-molecular-weight DNA associated with intracytoplasmic A-particle inclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370067"}
{"pmid": "4370066", "title": "Heterogeneity in the methylation and 5' termini of Novikoff ascites hepatoma 5.8 S ribosomal RNA.", "content": "Heterogeneity in the methylation and 5' termini of Novikoff ascites hepatoma 5.8 S ribosomal RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370066"}
{"pmid": "4370068", "title": "Histochemical evidence of cyclic nucleotide phosphodiesterase in photoreceptor outer segments.", "content": "Histochemical evidence of cyclic nucleotide phosphodiesterase in photoreceptor outer segments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370068"}
{"pmid": "4370069", "title": "Histochemical observations on the enzymes of chicken yolk sac membrane.", "content": "Histochemical observations on the enzymes of chicken yolk sac membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370069"}
{"pmid": "4370070", "title": "Hormonal control of lipolysis in adipose tissue.", "content": "Hormonal control of lipolysis in adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370070"}
{"pmid": "4370071", "title": "Hormonal control of oestrogen receptor in uterus and receptivity for ovoimplantation in the rat.", "content": "Hormonal control of oestrogen receptor in uterus and receptivity for ovoimplantation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370071"}
{"pmid": "4370072", "title": "Hormone control of heme synthesis in cultures of human fetal liver cells.", "content": "Hormone control of heme synthesis in cultures of human fetal liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370072"}
{"pmid": "4370073", "title": "Host defense mechanisms against infection with influenza virus. I. Effect of sensitized spleen cells on infection in vitro.", "content": "Host defense mechanisms against infection with influenza virus. I. Effect of sensitized spleen cells on infection in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370073"}
{"pmid": "4370074", "title": "Housing for the disabled: a follow-up study.", "content": "Housing for the disabled: a follow-up study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370074"}
{"pmid": "4370075", "title": "Human cataract and galactose metabolism.", "content": "Human cataract and galactose metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370075"}
{"pmid": "4370076", "title": "Hydatid cysts of the kidney. Simulating similar kidney lesions.", "content": "Hydatid cysts of the kidney. Simulating similar kidney lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370076"}
{"pmid": "4370077", "title": "Hypercalcaemia of neoplasia, parathyroid hormone and vitamin D: studies in parabiosis.", "content": "Hypercalcaemia of neoplasia, parathyroid hormone and vitamin D: studies in parabiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370077"}
{"pmid": "4370079", "title": "Hyperpigmentation on cortisone after adrenalectomy for primary aldosteronism.", "content": "Hyperpigmentation on cortisone after adrenalectomy for primary aldosteronism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370079"}
{"pmid": "4370078", "title": "Hypercholesterolemia and hypertriglyceridemia in children. A pediatric approach to primary atherosclerosis prevention.", "content": "Hypercholesterolemia and hypertriglyceridemia in children. A pediatric approach to primary atherosclerosis prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370078"}
{"pmid": "4370080", "title": "Hypnotic effects of L-tryptophan.", "content": "Hypnotic effects of L-tryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370080"}
{"pmid": "4370081", "title": "Hypolipidemic drugs and lipoprotein metabolism.", "content": "Hypolipidemic drugs and lipoprotein metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370081"}
{"pmid": "4370082", "title": "Hypothalamic control of secretion and release of prolactin.", "content": "Hypothalamic control of secretion and release of prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370082"}
{"pmid": "4370083", "title": "Identification of a poison in toxic scallops from a Gonyaulax tamarensis red tide.", "content": "Identification of a poison in toxic scallops from a Gonyaulax tamarensis red tide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370083"}
{"pmid": "4370085", "title": "IgM antibodies specific for Epstein-Barr virus in infectious mononucleosis without heterophil antibodies.", "content": "IgM antibodies specific for Epstein-Barr virus in infectious mononucleosis without heterophil antibodies. IgM antibodies specific for Epstein-Barr (E.B.) virus were demonstrable in all but one out of 46 patients diagnosed as having infectious mononucleosis wihout heterophil antibodies; cytomegalovirus aetiology was excluded. In all but two cases the highest titre was found in the first sample. In 21 patients a significant decrease was seen within a few weeks. IgG antibodies to E.B. virus, mostly remaining at a constant level, were demonstrable in all cases. IgM antibodies to E.B. virus were found in only five out of 300 controls.The results suggest that in a disease similar to infectious mononucleosis without heterophil antibodies testing of transient E.B. virus-specific IgM antibodies makes a rapid aetiological diagnosis possible and that in clinically well-defined cases viruses other than E.B. virus and cytomegalovirus are unlikely to be causal agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370085"}
{"pmid": "4370084", "title": "Identity of structure of ovine and bovine ACTH: correction of revised structure of the ovine hormone.", "content": "Identity of structure of ovine and bovine ACTH: correction of revised structure of the ovine hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370084"}
{"pmid": "4370086", "title": "Imidazole derivatives as inhibitors of cyclic nucleotide phosphodiesterases.", "content": "Imidazole derivatives as inhibitors of cyclic nucleotide phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370086"}
{"pmid": "4370087", "title": "Immunofluorescence staining for the diagnosis of herpes encephalitis.", "content": "Immunofluorescence staining for the diagnosis of herpes encephalitis. Direct immunofluorescence staining for herpes simplex virus was applied to cryostat sections of 43 specimens removed at brain biopsy. Herpes antigen was found in 10 specimens and virus was isolated from them. Antigen was found in one specimen from which virus was not isolated. Two specimens from which virus was isolated gave equivocal fluorescence. Thirty specimens gave no fluorescence or live virus. Immunofluorescence provided a diagnosis in three hr compared with 24-42 hr for virus isolation. Indirect immunofluorescence staining was applied to sections of brain removed at necropsy and fixed in formalin. Herpes antigen was found in sections of six of the 12 brains examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370087"}
{"pmid": "4370089", "title": "Immunopurification of phospholipase C (alpha-toxin) from Clostridium perfringens.", "content": "Immunopurification of phospholipase C (alpha-toxin) from Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370089"}
{"pmid": "4370088", "title": "Immunological phagocytosis: effect of drugs on phosphodiesterase activity.", "content": "Immunological phagocytosis: effect of drugs on phosphodiesterase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370088"}
{"pmid": "4370090", "title": "Implications of secretory immune system in viral infections.", "content": "Implications of secretory immune system in viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370090"}
{"pmid": "4370091", "title": "Importance of age of host in detecting tumor-associated transplantation antigens.", "content": "Importance of age of host in detecting tumor-associated transplantation antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370091"}
{"pmid": "4370092", "title": "Importance of testes in induction of hyperplastic nodules, carcinomas, and cirrhosis of liver in A times C male rats ingesting 0.025 percent N-2-fluorenyldiacetamide.", "content": "Importance of testes in induction of hyperplastic nodules, carcinomas, and cirrhosis of liver in A times C male rats ingesting 0.025 percent N-2-fluorenyldiacetamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370092"}
{"pmid": "4370093", "title": "In situ characterisation of photosynthetic electron transport in Rhodopseudomonas capsulata.", "content": "In situ characterisation of photosynthetic electron transport in Rhodopseudomonas capsulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370093"}
{"pmid": "4370095", "title": "In vivo subunit hybridization of succinic semialdehyde and 4-aminobutanal dehydrogenases from a Pseudomonas species.", "content": "In vivo subunit hybridization of succinic semialdehyde and 4-aminobutanal dehydrogenases from a Pseudomonas species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370095"}
{"pmid": "4370096", "title": "Increase in the amount of iodide released from the thyroid after perchlorate or carbimazole administration.", "content": "Increase in the amount of iodide released from the thyroid after perchlorate or carbimazole administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370096"}
{"pmid": "4370099", "title": "Infectious diseases in children with cancer.", "content": "Infectious diseases in children with cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370099"}
{"pmid": "4370097", "title": "Increased collagen synthesis in blood vessels of hypertensive rats and its reversal by antihypertensive agents.", "content": "Increased collagen synthesis in blood vessels of hypertensive rats and its reversal by antihypertensive agents. Collagen synthesis is increased in the aortas, mesenteric arteries, and to a lesser extent, in the hearts of rats either made hypertensive with desoxycorticosterone acetate-salt or that are spontaneously hypertensive. Several markers of collagen biosynthesis were shown to be increased, including prolyl hydroxylase (EC 1.14.11.2; proline, 2-oxoglutarate dioxygenase), prolyl hydroxylase-related antigen, total collagen content, and the incorporation of [(3)H]proline into total protein and into collagen. The antihypertensive agents chlorothiazide and reserpine, when administered before the onset of hypertension in the rats treated with desoxycorticosterone acetate-salt, prevented or diminished the increase in collagen biosynthesis. When reserpine was given after the onset of hypertension, prolyl hydroxylase activity was decreased concomitant with the decrease in blood pressure. Treatment with reserpine is particularly effective in diminishing arterial prolyl hydroxylase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370097"}
{"pmid": "4370098", "title": "Induction of respiratory-deficient mutants in a \"petite negative\" yeast species Kluyveromyces lactis with N-methyl-N'-nitro-N-nitrosoguanidine.", "content": "Induction of respiratory-deficient mutants in a \"petite negative\" yeast species Kluyveromyces lactis with N-methyl-N'-nitro-N-nitrosoguanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370098"}
{"pmid": "4370100", "title": "Infectious mononucleosis.", "content": "Infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370100"}
{"pmid": "4370094", "title": "In vivo study of mechanism of propranolol-induced blockade or neuromuscular transmission.", "content": "In vivo study of mechanism of propranolol-induced blockade or neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370094"}
{"pmid": "4370102", "title": "Influenza virus antigen in postencephalitic parkinsonism brain. Detection by immunofluorescence.", "content": "Influenza virus antigen in postencephalitic parkinsonism brain. Detection by immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370102"}
{"pmid": "4370103", "title": "Inhibition of human leucocyte collagenase by some drugs used in the therapy of rheumatic diseases.", "content": "Inhibition of human leucocyte collagenase by some drugs used in the therapy of rheumatic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370103"}
{"pmid": "4370104", "title": "Inhibition of interferon action by plant lectins.", "content": "Inhibition of interferon action by plant lectins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370104"}
{"pmid": "4370106", "title": "Inhibition of platelet adherence to a collagen-coated surface by agents that inhibit platelet shape change and clot retraction.", "content": "Inhibition of platelet adherence to a collagen-coated surface by agents that inhibit platelet shape change and clot retraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370106"}
{"pmid": "4370105", "title": "Inhibition of membrane adenosine triphosphatase by alpha-tocopherol and its derivatives.", "content": "Inhibition of membrane adenosine triphosphatase by alpha-tocopherol and its derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370105"}
{"pmid": "4370107", "title": "Inhibition of transport systems in cultured rat hepatoma cells by colcemid and ethanol.", "content": "Inhibition of transport systems in cultured rat hepatoma cells by colcemid and ethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370107"}
{"pmid": "4370108", "title": "Inhibitors against rabies virus present in normal rabbit sera.", "content": "Inhibitors against rabies virus present in normal rabbit sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370108"}
{"pmid": "4370109", "title": "Inhibitors of inositol cyclase (D-glucose 6-phosphate-1L-myoinositol 1-phosphate cycloaldolase) from rat testis.", "content": "Inhibitors of inositol cyclase (D-glucose 6-phosphate-1L-myoinositol 1-phosphate cycloaldolase) from rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370109"}
{"pmid": "4370101", "title": "Inferences from protein and nucleic acid sequences: early molecular evolution, divergence of kingdoms and rates of change.", "content": "Inferences from protein and nucleic acid sequences: early molecular evolution, divergence of kingdoms and rates of change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370101"}
{"pmid": "4370110", "title": "Inhibitory action of thyroid hormone of the activation of adenyl cyclase-cyclic AMP system by thyroid-stimulating hormone in human thyroid tissues from euthyroid subjects and thyrotoxic patients.", "content": "Inhibitory action of thyroid hormone of the activation of adenyl cyclase-cyclic AMP system by thyroid-stimulating hormone in human thyroid tissues from euthyroid subjects and thyrotoxic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370110"}
{"pmid": "4370111", "title": "Inhibitory effects of dibutyryl and cyclic AMP on the compound action potential in the frog (Rana pipiens) sciatic nerve.", "content": "Inhibitory effects of dibutyryl and cyclic AMP on the compound action potential in the frog (Rana pipiens) sciatic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370111"}
{"pmid": "4370112", "title": "Inhibitory processes and interneuronal apparatus in motor cortex during sleep and waking. I. Background firing and responsiveness of pyramidal tract neurons and interneurons.", "content": "Inhibitory processes and interneuronal apparatus in motor cortex during sleep and waking. I. Background firing and responsiveness of pyramidal tract neurons and interneurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370112"}
{"pmid": "4370113", "title": "Inhibitory processes and interneuronal apparatus in motor cortex during sleep and waking. II. Recurrent and afferent inhibition of pyramidal tract neurons.", "content": "Inhibitory processes and interneuronal apparatus in motor cortex during sleep and waking. II. Recurrent and afferent inhibition of pyramidal tract neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370113"}
{"pmid": "4370114", "title": "Intensive transfusion therapy in thalassemia major: an eight-year follow-up.", "content": "Intensive transfusion therapy in thalassemia major: an eight-year follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370114"}
{"pmid": "4370115", "title": "Interaction between dehydroepiandrosterone, cyclic adenosine-3',5'-monophosphate and glucose-6-phosphate-dehydrogenase in normal and diseased subjects.", "content": "Interaction between dehydroepiandrosterone, cyclic adenosine-3',5'-monophosphate and glucose-6-phosphate-dehydrogenase in normal and diseased subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370115"}
{"pmid": "4370116", "title": "Interaction of angiotensin peptides and of amino acids with p-nitrophenyl acetate.", "content": "Interaction of angiotensin peptides and of amino acids with p-nitrophenyl acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370116"}
{"pmid": "4370117", "title": "Interaction of human serum high density lipoprotein apoprotein with phospholipids.", "content": "Interaction of human serum high density lipoprotein apoprotein with phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370117"}
{"pmid": "4370118", "title": "Interaction of manganous ion, substrates, and anions with arginine kinase. Magnetic relaxation rate studies of water protons and kinetic anion effects.", "content": "Interaction of manganous ion, substrates, and anions with arginine kinase. Magnetic relaxation rate studies of water protons and kinetic anion effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370118"}
{"pmid": "4370120", "title": "Interactions between the prostaglandins and steroid hormones.", "content": "Interactions between the prostaglandins and steroid hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370120"}
{"pmid": "4370122", "title": "Intravenous nutrition of newborn infants with lipid.", "content": "Intravenous nutrition of newborn infants with lipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370122"}
{"pmid": "4370123", "title": "Intussusception as a complication of malignant neoplasm.", "content": "Intussusception as a complication of malignant neoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370123"}
{"pmid": "4370126", "title": "Ion pair partition chromatography in the bioanalysis of alprenolol-(3H) and alprenolol metabolites.", "content": "Ion pair partition chromatography in the bioanalysis of alprenolol-(3H) and alprenolol metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370126"}
{"pmid": "4370125", "title": "Iodinated derivatives of adrenocorticotropic hormone. Preparation of iodinated alpha 1-24-ACTH with full hormonal activity.", "content": "Iodinated derivatives of adrenocorticotropic hormone. Preparation of iodinated alpha 1-24-ACTH with full hormonal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370125"}
{"pmid": "4370127", "title": "Is chloramphenicol the drug of choice for the treatment of enteric fever? Comparative studies on the effects of chloramphenicol, trimethoprim-sulphametoxazole and beta-lactam antibiotics.", "content": "Is chloramphenicol the drug of choice for the treatment of enteric fever? Comparative studies on the effects of chloramphenicol, trimethoprim-sulphametoxazole and beta-lactam antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370127"}
{"pmid": "4370129", "title": "Isolation and characterization of bovine parainfluenza type 3 virus from cattle in Kenya.", "content": "Isolation and characterization of bovine parainfluenza type 3 virus from cattle in Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370129"}
{"pmid": "4370119", "title": "Interaction of neomycin with phosphoinositide metabolism in guinea pig inner ear and brain tissues.", "content": "Interaction of neomycin with phosphoinositide metabolism in guinea pig inner ear and brain tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370119"}
{"pmid": "4370128", "title": "Isolation and analysis of human plasma lipoproteins accumulating postrandial in an intermediate density fraction (d 1.006--1.019 g-ml).", "content": "Isolation and analysis of human plasma lipoproteins accumulating postrandial in an intermediate density fraction (d 1.006--1.019 g-ml).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370128"}
{"pmid": "4370130", "title": "Isolation and fractionation of porcine peripheral lymphocytes.", "content": "Isolation and fractionation of porcine peripheral lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370130"}
{"pmid": "4370131", "title": "Isolation and identification of an O-(2-hydroxypropyl)-maltose from the faeces of rats fed with O-(hyroxypropyl)starch.", "content": "Isolation and identification of an O-(2-hydroxypropyl)-maltose from the faeces of rats fed with O-(hyroxypropyl)starch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370131"}
{"pmid": "4370132", "title": "Isolation and properties of protein component as activator for anthranilamide hydroxylation in rat liver.", "content": "Isolation and properties of protein component as activator for anthranilamide hydroxylation in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370132"}
{"pmid": "4370121", "title": "Interferon production by lymphocytes from patients with systemic lupus erythematosus.", "content": "Interferon production by lymphocytes from patients with systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370121"}
{"pmid": "4370133", "title": "Isolation and protein pattern of eye lens fiber junctions.", "content": "Isolation and protein pattern of eye lens fiber junctions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370133"}
{"pmid": "4370135", "title": "Isolation of plasma membranes from normal and 1-beta-D arabinofuranosylcytosine transformed hamster embryo fibroblasts.", "content": "Isolation of plasma membranes from normal and 1-beta-D arabinofuranosylcytosine transformed hamster embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370135"}
{"pmid": "4370136", "title": "Kinetic and molecular properties of lysine-sensitive aspartokinase. Factors influencing the lysine-mediated association reaction and their relationship to the cooperativity of lysine inhibition.", "content": "Kinetic and molecular properties of lysine-sensitive aspartokinase. Factors influencing the lysine-mediated association reaction and their relationship to the cooperativity of lysine inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370136"}
{"pmid": "4370137", "title": "Kinetic studies of the oxidation of ferrocytochrome c from horse heart and Candida krusei by tris(1,10-phenanthroline)cobalt(3).", "content": "Kinetic studies of the oxidation of ferrocytochrome c from horse heart and Candida krusei by tris(1,10-phenanthroline)cobalt(3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370137"}
{"pmid": "4370138", "title": "Kinetics and electron paramagnetic resonance spectra of vanadyl(IV) carboxypeptidase A.", "content": "Kinetics and electron paramagnetic resonance spectra of vanadyl(IV) carboxypeptidase A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370138"}
{"pmid": "4370139", "title": "Labeling of the external surface of hamster and mouse fibroblasts with (14C)sialic acid.", "content": "Labeling of the external surface of hamster and mouse fibroblasts with (14C)sialic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370139"}
{"pmid": "4370141", "title": "Lactate stimulation of renal cortical adenylate cyclase: a mechanism for erythropoietin production following cobalt treatment or hypoxia.", "content": "Lactate stimulation of renal cortical adenylate cyclase: a mechanism for erythropoietin production following cobalt treatment or hypoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370141"}
{"pmid": "4370140", "title": "Laboratory test results altered by \"The Pill\".", "content": "Laboratory test results altered by \"The Pill\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370140"}
{"pmid": "4370142", "title": "Late field responses in optic tectum of the pigeon.", "content": "Late field responses in optic tectum of the pigeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370142"}
{"pmid": "4370143", "title": "Lead neuropathy and sickle cell disease.", "content": "Lead neuropathy and sickle cell disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370143"}
{"pmid": "4370145", "title": "Letter: Alcohol and alpha-lipoprotein cholesterol.", "content": "Letter: Alcohol and alpha-lipoprotein cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370145"}
{"pmid": "4370144", "title": "Letter to the editor: Differences between in vivo and in vitro actions of prostaglandins in corpus luteum: is there a paradox?", "content": "Letter to the editor: Differences between in vivo and in vitro actions of prostaglandins in corpus luteum: is there a paradox?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370144"}
{"pmid": "4370146", "title": "Letter: Assay for carcinoembryonic antigen.", "content": "Letter: Assay for carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370146"}
{"pmid": "4370147", "title": "Letter: Congenital mesoblastic nephroma.", "content": "Letter: Congenital mesoblastic nephroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370147"}
{"pmid": "4370148", "title": "Letter: Diagnosis of insulinomas.", "content": "Letter: Diagnosis of insulinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370148"}
{"pmid": "4370134", "title": "Isolation of infectious DNA from avian myeloblastosis virus transformed leukemic cells.", "content": "Isolation of infectious DNA from avian myeloblastosis virus transformed leukemic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370134"}
{"pmid": "4370149", "title": "Letter: Experimental infection of a horse with an equine adenovirus.", "content": "Letter: Experimental infection of a horse with an equine adenovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370149"}
{"pmid": "4370150", "title": "Letter: Glioblastoma multiforme.", "content": "Letter: Glioblastoma multiforme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370150"}
{"pmid": "4370151", "title": "Letter: Immobilization of trypsin on partially oxidized cellulose.", "content": "Letter: Immobilization of trypsin on partially oxidized cellulose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370151"}
{"pmid": "4370153", "title": "Letter: Malabsorption in overland travellers to India.", "content": "Letter: Malabsorption in overland travellers to India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370153"}
{"pmid": "4370154", "title": "Letter: Nutrient deficiencies after intensive parenteral alimentation.", "content": "Letter: Nutrient deficiencies after intensive parenteral alimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370154"}
{"pmid": "4370152", "title": "Letter: Indomethacin, prostaglandin and hypercalcemia.", "content": "Letter: Indomethacin, prostaglandin and hypercalcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370152"}
{"pmid": "4370155", "title": "Letter: NAD and chronic schizophrenia.", "content": "Letter: NAD and chronic schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370155"}
{"pmid": "4370156", "title": "Letter: On continuity of care.", "content": "Letter: On continuity of care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370156"}
{"pmid": "4370157", "title": "Letter: Other causes of petechiae.", "content": "Letter: Other causes of petechiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370157"}
{"pmid": "4370158", "title": "Letter: Photoinactivation therapy and herpes simplex.", "content": "Letter: Photoinactivation therapy and herpes simplex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370158"}
{"pmid": "4370160", "title": "Letter: Tinel's sign and Laplace's Law.", "content": "Letter: Tinel's sign and Laplace's Law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370160"}
{"pmid": "4370159", "title": "Letter: The oncogenic potential of dye-light treatment of herpetic lesions.", "content": "Letter: The oncogenic potential of dye-light treatment of herpetic lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370159"}
{"pmid": "4370161", "title": "Letter: Viscosity of cellular protoplasm: what do spin probes tell us?", "content": "Letter: Viscosity of cellular protoplasm: what do spin probes tell us?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370161"}
{"pmid": "4370162", "title": "Letter: Zoster in families.", "content": "Letter: Zoster in families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370162"}
{"pmid": "4370163", "title": "Light, electron microscopical, and histochemical study of motor nerve cells in spinal cord of hibernating and non-hibernating hedgehog.", "content": "Light, electron microscopical, and histochemical study of motor nerve cells in spinal cord of hibernating and non-hibernating hedgehog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370163"}
{"pmid": "4370165", "title": "Lipid phase transitions in membrane vesicles from Thermoplasma acidophila.", "content": "Lipid phase transitions in membrane vesicles from Thermoplasma acidophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370165"}
{"pmid": "4370166", "title": "Lipolysis, aging, and hormones.", "content": "Lipolysis, aging, and hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370166"}
{"pmid": "4370168", "title": "Lipoprotein fractions in maternal, cord and newborn serum.", "content": "Lipoprotein fractions in maternal, cord and newborn serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370168"}
{"pmid": "4370167", "title": "Lipolytic effects of sheep beta-lipotropin in rat adipose tissue: interaction with theophylline and dihydroergotamine.", "content": "Lipolytic effects of sheep beta-lipotropin in rat adipose tissue: interaction with theophylline and dihydroergotamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370167"}
{"pmid": "4370169", "title": "Lipoprotein lipase: comparative properties of the membrane-supported and solubilized enzyme species.", "content": "Lipoprotein lipase: comparative properties of the membrane-supported and solubilized enzyme species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370169"}
{"pmid": "4370170", "title": "Lipoproteins and lipids in diabetics with and without coronary heart disease.", "content": "Lipoproteins and lipids in diabetics with and without coronary heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370170"}
{"pmid": "4370171", "title": "Liver disease in transplanted patients.", "content": "Liver disease in transplanted patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370171"}
{"pmid": "4370172", "title": "Local, reflex, and central commands controlling gill and siphon movements in Aplysia.", "content": "Local, reflex, and central commands controlling gill and siphon movements in Aplysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370172"}
{"pmid": "4370173", "title": "Localization of alpha-fetoprotein by immunofluorescence in hyperplastic nodules during hepatocarcinogenesis induced by 2-acetylaminofluorene.", "content": "Localization of alpha-fetoprotein by immunofluorescence in hyperplastic nodules during hepatocarcinogenesis induced by 2-acetylaminofluorene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370173"}
{"pmid": "4370174", "title": "Location of intrahypothalamic estrogen-responsive sites influencing LH secretion in the female Rhesus monkey.", "content": "Location of intrahypothalamic estrogen-responsive sites influencing LH secretion in the female Rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370174"}
{"pmid": "4370164", "title": "Linoleate oxidation products and cardiovascular lesions.", "content": "Linoleate oxidation products and cardiovascular lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370164"}
{"pmid": "4370176", "title": "Lung cancer: assessment and selective management.", "content": "Lung cancer: assessment and selective management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370176"}
{"pmid": "4370175", "title": "Lumbar myelography and adhesive arachnoiditis.", "content": "Lumbar myelography and adhesive arachnoiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370175"}
{"pmid": "4370177", "title": "Luteotrophic factors in the cow: evidence for LH rather than prolactin.", "content": "Luteotrophic factors in the cow: evidence for LH rather than prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370177"}
{"pmid": "4370178", "title": "Magnetic resonance study of spin-labelled rhodopsin.", "content": "Magnetic resonance study of spin-labelled rhodopsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370178"}
{"pmid": "4370179", "title": "Malignant lymphoma with intracytoplasmic IgM crystalline inclusions.", "content": "Malignant lymphoma with intracytoplasmic IgM crystalline inclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370179"}
{"pmid": "4370180", "title": "Malignant mesenchymal tumors of the uterine corpus.", "content": "Malignant mesenchymal tumors of the uterine corpus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370180"}
{"pmid": "4370182", "title": "Mammographic varicosities indicative of a superior mediastinal syndrome. A case report.", "content": "Mammographic varicosities indicative of a superior mediastinal syndrome. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370182"}
{"pmid": "4370181", "title": "Malignant tumours following immunosuppression in renal transplantation.", "content": "Malignant tumours following immunosuppression in renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370181"}
{"pmid": "4370183", "title": "Marine sterols. V. Isolation and structure of occelasterol, a new 27-norergostane-type sterol, from an annelida, Pseudopotamilla occelata.", "content": "Marine sterols. V. Isolation and structure of occelasterol, a new 27-norergostane-type sterol, from an annelida, Pseudopotamilla occelata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370183"}
{"pmid": "4370184", "title": "Maternal adrenocorticotrophic hormone and cortisol during labour and vaginal delivery.", "content": "Maternal adrenocorticotrophic hormone and cortisol during labour and vaginal delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370184"}
{"pmid": "4370185", "title": "Measurement of angiotensin II in an ultrafiltrate of plasma.", "content": "Measurement of angiotensin II in an ultrafiltrate of plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370185"}
{"pmid": "4370186", "title": "Mechanism of adenosine triphosphate-dependent Ca2+ uptake of brain microsomes.", "content": "Mechanism of adenosine triphosphate-dependent Ca2+ uptake of brain microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370186"}
{"pmid": "4370187", "title": "Mechanisms controlling maternal placental circulation.", "content": "Mechanisms controlling maternal placental circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370187"}
{"pmid": "4370188", "title": "Mechanisms of drug action on recovery processes of cardiac muscle in myocardial infarction.", "content": "Mechanisms of drug action on recovery processes of cardiac muscle in myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370188"}
{"pmid": "4370189", "title": "Mechanisms of hyperlipoproteinemia.", "content": "Mechanisms of hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370189"}
{"pmid": "4370191", "title": "Mechanisms of steroid resistance.", "content": "Mechanisms of steroid resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370191"}
{"pmid": "4370190", "title": "Mechanisms of insulin action.", "content": "Mechanisms of insulin action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370190"}
{"pmid": "4370193", "title": "Metabolic regulation of steroidogenesis in isolated adrenal cells of rat. Effect of actinomycin D on cGMP-induced steroidogenesis.", "content": "Metabolic regulation of steroidogenesis in isolated adrenal cells of rat. Effect of actinomycin D on cGMP-induced steroidogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370193"}
{"pmid": "4370192", "title": "Mechanisms underlying vasomotor regulation of regional pulmonary blood flow in normal and disease states.", "content": "Mechanisms underlying vasomotor regulation of regional pulmonary blood flow in normal and disease states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370192"}
{"pmid": "4370194", "title": "Metabolic regulation of steroidogenesis in isolated adrenal cells of the rat. ACTH regulation of cGMP and cAMP levels and steroidogenesis.", "content": "Metabolic regulation of steroidogenesis in isolated adrenal cells of the rat. ACTH regulation of cGMP and cAMP levels and steroidogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370194"}
{"pmid": "4370195", "title": "Methionine metabolism in pyridoxine deficiency.", "content": "Methionine metabolism in pyridoxine deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370195"}
{"pmid": "4370196", "title": "Microcirculatory effects of prostaglandins E1, E2, and A1 in the rat mesentery and cremaster muscle.", "content": "Microcirculatory effects of prostaglandins E1, E2, and A1 in the rat mesentery and cremaster muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370196"}
{"pmid": "4370198", "title": "Mitochondrial membranes of inositol-requiring Saccharomyces carlsbergensis: covalent binding of a radioactive marker to the outer membrane.", "content": "Mitochondrial membranes of inositol-requiring Saccharomyces carlsbergensis: covalent binding of a radioactive marker to the outer membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370198"}
{"pmid": "4370200", "title": "Mode of action of chronotropic agents in cardiac Purkinje fibers. Does epinephrine act by directly modifying the external surface charge?", "content": "Mode of action of chronotropic agents in cardiac Purkinje fibers. Does epinephrine act by directly modifying the external surface charge? Hauswirth et al. (1968) proposed that epinephrine acts on i(KK2) by adding its own positive charge to the external membrane surface near the i(KK2) channel. This hypothesis was tested by using noncationic compounds, theophylline and R07-2956, which mimicked epinephrine's effects on pacemaker activity and on i(KK2). In maximally effective doses, theophylline or R07-2956 occluded the effect of epinephrine, indicating a shared final common mechanism. Since theophylline and R07-2956 are noncationic at pH 7.4, the common mechanism cannot be a direct change in external surface charge. On the contrary, epinephrine does not interfere with the voltage shift produced by La(+++), which is thought to modify the external surface charge. The results argue against the original hypothesis but leave open the possibility that an alteration in internal surface charge generates the observed voltage shift. The potency of theophylline and R07-2956 as phosphodiesterase inhibitors suggests that the final common mechanism begins with the elevation of intracellular cyclic AMP, leading to a saturable process which limits the voltage shift's magnitude. This hypothesis is used to generate dose-response curves describing the combined effects of epinephrine and theophylline, and these are compared with experimental data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370200"}
{"pmid": "4370199", "title": "Mode of action of cholera toxin: stabilization of catecholamine-sensitive adenylate cyclase in turkey erythrocytes.", "content": "Mode of action of cholera toxin: stabilization of catecholamine-sensitive adenylate cyclase in turkey erythrocytes. Preincubating turkey erythrocytes with cholera toxin alters their adenylate cyclase (EC 4.6.1.1) system: basal activity, maximal epinephrine-stimulatable activity, and affinity of the enzyme reaction for epinephrine are all increased. Pretreatment of erythrocytes with choleragenoid prevents these changes. Cholera toxin does not alter [(3)H]epinephrine uptake by intact erythrocytes. The increase in epinephrine-stimulatable cyclase activity appears to occur at the expense of fluoride-stimulatable activity, which is decreased by the toxin. In lysates from both toxin-treated and control cells, maximally stimulating amounts of epinephrine and fluoride, when added in combination, have a nearly additive effect on cyclase activity. These observations suggest that the adenylate cyclase system of the turkey erythrocyte may exist in two interconvertible forms, one that is catecholamine-responsive but fluoride-insensitive, and another that is fluoride-sensitive but not coupled to catecholamine receptors. Cholera toxin appears to stabilize the enzyme in its hormone receptor-coupled form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370199"}
{"pmid": "4370203", "title": "Modification of neuron properties by electrotonic synapses. II. Burst formation by electrotonic synapses.", "content": "Modification of neuron properties by electrotonic synapses. II. Burst formation by electrotonic synapses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370203"}
{"pmid": "4370202", "title": "Modification of neuron properties by electrotonic synapses. I. Input resistance, time constant, and integration.", "content": "Modification of neuron properties by electrotonic synapses. I. Input resistance, time constant, and integration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370202"}
{"pmid": "4370201", "title": "Model of molecular mechanism able to generate a depolarization-hyperpolarization cycle.", "content": "Model of molecular mechanism able to generate a depolarization-hyperpolarization cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370201"}
{"pmid": "4370197", "title": "Middle ear masses mimicking glomus tumors: radiographic and otoscopic recognition.", "content": "Middle ear masses mimicking glomus tumors: radiographic and otoscopic recognition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370197"}
{"pmid": "4370204", "title": "Modulation of malate dehydrogenase of young and old rats by various effectors.", "content": "Modulation of malate dehydrogenase of young and old rats by various effectors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370204"}
{"pmid": "4370205", "title": "Monovalent cation requirement for ADP inhibition of pyruvate dehydrogenase kinase.", "content": "Monovalent cation requirement for ADP inhibition of pyruvate dehydrogenase kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370205"}
{"pmid": "4370207", "title": "Multiple forms of cyclic 3',5'-AMP phosphodiesterase of rat cerebrum and cloned astrocytoma and neuroblastoma cells.", "content": "Multiple forms of cyclic 3',5'-AMP phosphodiesterase of rat cerebrum and cloned astrocytoma and neuroblastoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370207"}
{"pmid": "4370208", "title": "Multiple glomus tumours.", "content": "Multiple glomus tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370208"}
{"pmid": "4370210", "title": "Mutagenic action of methyl methane sulphonate on the bluegreen alga Anacystis nidulans.", "content": "Mutagenic action of methyl methane sulphonate on the bluegreen alga Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370210"}
{"pmid": "4370209", "title": "Murine sarcoma virus gene expression: transformants which express viral envelope glycoprotein in the absence of the major internal protein and infectious particles.", "content": "Murine sarcoma virus gene expression: transformants which express viral envelope glycoprotein in the absence of the major internal protein and infectious particles. Expression of the major internal protein and the envelope glycoprotein of murine C-type viruses in focus-derived lines of normal rat kidney cells infected with Kirsten murine sarcoma virus was measured by radioimmunoassay. Of the clones selected, which do not produce virus particles or the major viral structural protein, approximately half express the viral envelope glycoprotein at concentrations found in productively infected cells. Expression of the envelope glycoprotein did not appear to alter significantly the properties of the transformed cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370209"}
{"pmid": "4370211", "title": "Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells.", "content": "Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370211"}
{"pmid": "4370212", "title": "Myoepithelioma of the parotid gland.", "content": "Myoepithelioma of the parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370212"}
{"pmid": "4370213", "title": "Neoplasms of the kidney, renal pelvis and ureter. A study of 92 primary and 44 metastic tumours.", "content": "Neoplasms of the kidney, renal pelvis and ureter. A study of 92 primary and 44 metastic tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370213"}
{"pmid": "4370206", "title": "Multicentric reticulohistiocytosis. Fine structural analysis of the synovium and synovial fluid cells.", "content": "Multicentric reticulohistiocytosis. Fine structural analysis of the synovium and synovial fluid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370206"}
{"pmid": "4370214", "title": "Nephroblastoma with keratinising cysts--(a case report).", "content": "Nephroblastoma with keratinising cysts--(a case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370214"}
{"pmid": "4370216", "title": "Network analysis as a method for the evaluation of service delivery systems.", "content": "Network analysis as a method for the evaluation of service delivery systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370216"}
{"pmid": "4370215", "title": "Nephrotic syndrome with oat-cell carcinoma.", "content": "Nephrotic syndrome with oat-cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370215"}
{"pmid": "4370218", "title": "Neuroblastoma: drug-induced differentiation increases proportion of cytoplasmic RNA that contains polyadenylic acid.", "content": "Neuroblastoma: drug-induced differentiation increases proportion of cytoplasmic RNA that contains polyadenylic acid. The production of cytoplasmic RNA that contains polyadenylic acid is increased, relative to total cytoplasmic RNA, in a neuroblastoma clone, NBE-(A), after induction of differentiation by 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone, an inhibitor of adenosine 3',5'-monophosphate phosphodiesterase. The amount of RNA that contains polyadenylic acid in cytoplasm may be greater in such differentiated neuroblastoma cells than in proliferating control cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370218"}
{"pmid": "4370219", "title": "Neuronal activity before and during eye movements in thalamic internal medullary lamina of the cat.", "content": "Neuronal activity before and during eye movements in thalamic internal medullary lamina of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370219"}
{"pmid": "4370222", "title": "Night terrors.", "content": "Night terrors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370222"}
{"pmid": "4370221", "title": "New serotypes of reoviruses isolated from cattle.", "content": "New serotypes of reoviruses isolated from cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370221"}
{"pmid": "4370217", "title": "Neural origin of granular cell tumor.", "content": "Neural origin of granular cell tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370217"}
{"pmid": "4370223", "title": "Non-productive infection of genetically resistant mouse cells by murine cytomegalovirus.", "content": "Non-productive infection of genetically resistant mouse cells by murine cytomegalovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370223"}
{"pmid": "4370224", "title": "Non-specific immunostimulation in bronchogenic cancer.", "content": "Non-specific immunostimulation in bronchogenic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370224"}
{"pmid": "4370225", "title": "Nuclear bodies in endothelial cells of human glomeruli.", "content": "Nuclear bodies in endothelial cells of human glomeruli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370225"}
{"pmid": "4370226", "title": "Nuclear coupling of 33S and the nature of free radicals in irradiated crystals of cystine dihydrochloride.", "content": "Nuclear coupling of 33S and the nature of free radicals in irradiated crystals of cystine dihydrochloride. The (33)S hyperfine structure has been observed and analyzed in the electron spin resonance of gamma-irradiated single crystals of cystine dihydrochloride at 77 degrees K and at room temperature. The radicals observed at room temperature and previously assigned as RCH(2)S are proved to be disulfide radicals, RCH(2)SS. However, the RCH(2)S radical is identified by the (33)S measurements in samples irradiated at 77 degrees K, annealed at 200 degrees K, and observed at 77 degrees K. This monosulfide radical appears to undergo reactions to form disulfide radicals at room temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370226"}
{"pmid": "4370220", "title": "New approaches to the evaluation and treatment of insomnia. (Preliminary results).", "content": "New approaches to the evaluation and treatment of insomnia. (Preliminary results).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370220"}
{"pmid": "4370227", "title": "Nuclear magnetic resonance studies of cancer. V. Appearance and development of a tumor systemic effect in serum and tissues.", "content": "Nuclear magnetic resonance studies of cancer. V. Appearance and development of a tumor systemic effect in serum and tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370227"}
{"pmid": "4370229", "title": "Nuclear poly (ADPR) and mono (ADPR) residues in tissues with different growth rates.", "content": "Nuclear poly (ADPR) and mono (ADPR) residues in tissues with different growth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370229"}
{"pmid": "4370228", "title": "Nuclear magnetic resonance titration curves of histidine ring protons. V. Comparative study of cytochrome c from three species and the assignment of individual proton resonances.", "content": "Nuclear magnetic resonance titration curves of histidine ring protons. V. Comparative study of cytochrome c from three species and the assignment of individual proton resonances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370228"}
{"pmid": "4370230", "title": "Nucleoside peptides. 6. Synthesis of certain N-(5-amino-1-(beta-D-ribofuranosyl)imidazole-4-carbonyl)amino acids related to naturally occurring intermediates in the purine biosynthetic pathway.", "content": "Nucleoside peptides. 6. Synthesis of certain N-(5-amino-1-(beta-D-ribofuranosyl)imidazole-4-carbonyl)amino acids related to naturally occurring intermediates in the purine biosynthetic pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370230"}
{"pmid": "4370231", "title": "Nutrient media for plant-parasitic nematodes. VI. Nucleic acids content and nucleotide synthesis in Aphelenchoides rutgersi.", "content": "Nutrient media for plant-parasitic nematodes. VI. Nucleic acids content and nucleotide synthesis in Aphelenchoides rutgersi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370231"}
{"pmid": "4370233", "title": "Observations on experimental infection with infectious bovine rhinotracheitis virus in rabbits.", "content": "Observations on experimental infection with infectious bovine rhinotracheitis virus in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370233"}
{"pmid": "4370232", "title": "Observations and comments on two outbreaks of abortion associated with IBR virus infection.", "content": "Observations and comments on two outbreaks of abortion associated with IBR virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370232"}
{"pmid": "4370234", "title": "Observations on the first epidemic of foot-and-mouth disease type SAT 1 in Tanzania.", "content": "Observations on the first epidemic of foot-and-mouth disease type SAT 1 in Tanzania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370234"}
{"pmid": "4370235", "title": "Ocular manifestations of the mucopolysaccharidoses.", "content": "Ocular manifestations of the mucopolysaccharidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370235"}
{"pmid": "4370236", "title": "Olivopontocerebellar degeneration. Clinical and ultrastructural abnormalities.", "content": "Olivopontocerebellar degeneration. Clinical and ultrastructural abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370236"}
{"pmid": "4370237", "title": "On the limited peptic digestion of horse heart cytochrome C. isolation of C-terminal peptide sequences.", "content": "On the limited peptic digestion of horse heart cytochrome C. isolation of C-terminal peptide sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370237"}
{"pmid": "4370238", "title": "On the luminescence of estrogens.", "content": "On the luminescence of estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370238"}
{"pmid": "4370239", "title": "On the mechanism of uptake of iron by reticulocytes.", "content": "On the mechanism of uptake of iron by reticulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370239"}
{"pmid": "4370240", "title": "On the polypeptide composition of an abnormal high density lipoprotein (LP-E) occurring in LCAT-deficient plasma.", "content": "On the polypeptide composition of an abnormal high density lipoprotein (LP-E) occurring in LCAT-deficient plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370240"}
{"pmid": "4370242", "title": "Oncogenic activity of an m-dioxane derivatives: 2,6-dimethyl-m-dioxan-4-ol acetate (dimethoxane).", "content": "Oncogenic activity of an m-dioxane derivatives: 2,6-dimethyl-m-dioxan-4-ol acetate (dimethoxane).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370242"}
{"pmid": "4370241", "title": "On the relation of products of activated lymphocytes to cell-mediated cytolysis.", "content": "On the relation of products of activated lymphocytes to cell-mediated cytolysis. Experiments have been designed to test the hypothesis that soluble mediator production and T-cell-mediated cytotoxicity are necessarily related phenomena, and that soluble mediators may be involved in the mechanism of cytolysis. To this end, agents known to inhibit T-cell-mediated lysis in vitro have been studied for their effects on the production of two lymphocyte-derived mediators, lymphotoxin (LT) and migration inhibitory factor (MIF). A clear dissociation between mediator production and cell-mediated cytolysis was found using inhibitors of protein synthesis. Pactamycin and emetine, in doses of 10(-7) M to 10(-6) M, suppressed production of MIF and LT with only slight effect on killing of mastocytoma cells by immune T cells. On the other hand colchicine and vinblastine inhibited T-cell-mediated cytolysis in a dose-related manner but had no significant effect on either MIF or LT production, A striking dichotomy was also observed after augmentation of intracellular cyclic 3'5' adenosine monophosphate (cAMP) levels with cholera enterotoxin. Increased cAMP levels were associated with abrogation of direct lytic activity, but were without significant effect on MIF or LT production in guinea pigs or mice. These findings indicate that mediator production and direct lymphocyte-mediated cytolysis can be experimentally dissociated and represent independent cell-mediated immune functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370241"}
{"pmid": "4370243", "title": "Ontogeny of thirst in the rat: effects of hypertonic saline polyethylene glycol, and vena cava ligation.", "content": "Ontogeny of thirst in the rat: effects of hypertonic saline polyethylene glycol, and vena cava ligation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370243"}
{"pmid": "4370244", "title": "Oocyte maturation and follicle cell viability in vitro.", "content": "Oocyte maturation and follicle cell viability in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370244"}
{"pmid": "4370245", "title": "Organizational and attitudinal correlates of citizen board accomplishment in mental health and retardation.", "content": "Organizational and attitudinal correlates of citizen board accomplishment in mental health and retardation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370245"}
{"pmid": "4370246", "title": "Osteodystrophy of dialysed patients treated with vitamin D.", "content": "Osteodystrophy of dialysed patients treated with vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370246"}
{"pmid": "4370247", "title": "Paradoxical sleep in the chick (Gallus domesticus).", "content": "Paradoxical sleep in the chick (Gallus domesticus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370247"}
{"pmid": "4370248", "title": "Parathyroid hormone deficiency with Albright's hereditary osteodystrophy.", "content": "Parathyroid hormone deficiency with Albright's hereditary osteodystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370248"}
{"pmid": "4370249", "title": "Partial purification and characterization of the SV40 T antigen.", "content": "Partial purification and characterization of the SV40 T antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370249"}
{"pmid": "4370251", "title": "Partial purification of human interferon by affinity chromatography.", "content": "Partial purification of human interferon by affinity chromatography. Human interferon prepared by challenge of leukocytes with Sendai virus, or of fibroblasts with double-stranded poly(inosinic acid).poly(cytidylic acid), has been studied with respect to purification by affinity chromatography. Both leukocyte and fibroblast interferons are removed from crude tissue culture fluids by means of columns of antibody to leukocyte interferon attached to Sepharose-4B. The antibody was prepared in sheep using, as antigen, material that had been partially purified by gel filtration through Sephadex G-100 columns. Many of the impurities in the crude fibroblast interferon were presumably not recognized by the sheep antibodies induced by leukocyte interferon. Fibroblast interferon was, therefore, much more effectively purified as the result of this \"common denominator\" approach. The fibroblast product, in contrast to interferon from leukocytes, could only be harvested efficiently from the crude starting material when a carrier protein (bovine-serum albumin, and later, cytochrome c) was added to the eluting buffers to counteract losses, presumably due to adsorption on purification and assay equipment. Both varieties of interferon exhibit molecular weights of approximately 20,000-25,000, although association with higher molecular weight proteins occurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370251"}
{"pmid": "4370250", "title": "Partial purification and reconstitution of the heme oxygenase system from pig spleen microsomes.", "content": "Partial purification and reconstitution of the heme oxygenase system from pig spleen microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370250"}
{"pmid": "4370252", "title": "Pathological studies on adenocarcinoma of the uterine cervix in Singapore.", "content": "Pathological studies on adenocarcinoma of the uterine cervix in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370252"}
{"pmid": "4370253", "title": "Percutaneous needle aspiration lung biopsy.", "content": "Percutaneous needle aspiration lung biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370253"}
{"pmid": "4370254", "title": "Peripheral modification of thermoregulatory function during heat acclimation.", "content": "Peripheral modification of thermoregulatory function during heat acclimation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370254"}
{"pmid": "4370256", "title": "Pharyngoesophageal dysphagia and recurrent laryngeal nerve palsy.", "content": "Pharyngoesophageal dysphagia and recurrent laryngeal nerve palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370256"}
{"pmid": "4370255", "title": "Persistent noncytocidal vesicular stomatitis virus infections mediated by defective T particles that suppress virion transcriptase.", "content": "Persistent noncytocidal vesicular stomatitis virus infections mediated by defective T particles that suppress virion transcriptase. Infectious B virions of vesicular stomatitis virus were 100% lethal to BHK(21) (baby hamster kidney) cells when infecting alone, and persistent noncytocidal infection could not be achieved with cloned B virions alone. However, a mixture of B virions and homologous, short, defective, interfering particles (T particles) of a temperature-sensitive mutant of the virus regularly established persistently infected, noncytocidal carrier cultures. A long T particle was generated during establishment of the carrier culture; we show that this long T particle can establish and maintain persistent noncytocidal infection even when it infects cells along with virulent wild-type B virions. This long T particle causes the production of wild-type B virions with greatly reduced virion transcriptase (EC 2.7.7.6; RNA nucleotidyltransferase) levels when coinfecting the same cells, so it appears to prevent cytopathology by regulating virus transcription. The implications of these findings for rabies and other slowly progressing noncytocidal infections are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370255"}
{"pmid": "4370258", "title": "Phospholipid metabolism in the eggs and embryos of the sea urchin Arbacia punctulata.", "content": "Phospholipid metabolism in the eggs and embryos of the sea urchin Arbacia punctulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370258"}
{"pmid": "4370257", "title": "Phospholipid compositon of mitochondria and microsomes from regenerating rat liver and hepatomas of different growth rate.", "content": "Phospholipid compositon of mitochondria and microsomes from regenerating rat liver and hepatomas of different growth rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370257"}
{"pmid": "4370259", "title": "Phosphorylation of acid-soluble proteins in isolated nucleoli of Novikoff hepatoma ascites cells. Effects of divalent cations.", "content": "Phosphorylation of acid-soluble proteins in isolated nucleoli of Novikoff hepatoma ascites cells. Effects of divalent cations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370259"}
{"pmid": "4370260", "title": "Photophosphorylation not coupled to DCMU-insensitive photosystem II oxygen evolution.", "content": "Photophosphorylation not coupled to DCMU-insensitive photosystem II oxygen evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370260"}
{"pmid": "4370261", "title": "Physical-chemical studies of phospholipids and poly (amino acids) interactions.", "content": "Physical-chemical studies of phospholipids and poly (amino acids) interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370261"}
{"pmid": "4370262", "title": "Physiological and biochemical properties of neuromuscular transmission between identified motoneurons and gill muscle in Aplysia.", "content": "Physiological and biochemical properties of neuromuscular transmission between identified motoneurons and gill muscle in Aplysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370262"}
{"pmid": "4370263", "title": "Physiological properties of developing frog tadpole nerve-muscle junctions during repetitive stimulation.", "content": "Physiological properties of developing frog tadpole nerve-muscle junctions during repetitive stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370263"}
{"pmid": "4370264", "title": "Plasma adenosine 3',5'-monophosphate in antiinsulin-treated rats.", "content": "Plasma adenosine 3',5'-monophosphate in antiinsulin-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370264"}
{"pmid": "4370265", "title": "Plasma aldosterone during haemodialysis in patients with terminal renal failure.", "content": "Plasma aldosterone during haemodialysis in patients with terminal renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370265"}
{"pmid": "4370266", "title": "Plasminic activity and emotional stress.", "content": "Plasminic activity and emotional stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370266"}
{"pmid": "4370267", "title": "Platelet factor-3 availability and the platelet release reaction.", "content": "Platelet factor-3 availability and the platelet release reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370267"}
{"pmid": "4370268", "title": "Platelets as a source of fibroblast growth-promoting activity.", "content": "Platelets as a source of fibroblast growth-promoting activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370268"}
{"pmid": "4370269", "title": "Pneumocystis carinii pneumonia.", "content": "Pneumocystis carinii pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370269"}
{"pmid": "4370270", "title": "Poliomyelitis vaccination in Thailand. I. A pilot study of the administration of live poliomyelitis vaccine.", "content": "Poliomyelitis vaccination in Thailand. I. A pilot study of the administration of live poliomyelitis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370270"}
{"pmid": "4370272", "title": "Polymorphism of adenylate kinase (AK) and adenosine deaminase (ADA) in the Polish population.", "content": "Polymorphism of adenylate kinase (AK) and adenosine deaminase (ADA) in the Polish population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370272"}
{"pmid": "4370271", "title": "Poly(ADP-ribose): release of template restriction in HeLa cells.", "content": "Poly(ADP-ribose): release of template restriction in HeLa cells. Evidence is presented to show that ADP-ribosylation of nuclear proteins by poly(ADP-ribose) polymerase enhances template-primer activity of HeLa cell nuclear DNA. We used Escherichia coli DNA polymerase I (EC 2.7.7.7; DNA nucleotidyltransferase) as an exogenous probe of nuclear DNA status. Neither NAD nor free poly(ADP-ribose) acts directly on the bacterial enzyme. The stimulation is specific for formation of ADP-ribosylated proteins and is not a generalized polyanion or nucleotide effect on chromatin. The release of template restriction is proportional to the capacity of a given cell line to synthesize poly(ADP-ribose); both the stimulation and poly(ADP-ribose) formation are coordinately proportional to NAD concentration. Binding studies with DNA polymerase indicate exposure or generation of additional 3'-OH primer sites due to ADP-ribosylation in intact nuclei. With intact cells, there appears a correlation among growth, physiological template restriction, and the above effects of ADP-ribosylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370271"}
{"pmid": "4370273", "title": "Polysaccharide synthesis on immobilized phosphorylase.", "content": "Polysaccharide synthesis on immobilized phosphorylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370273"}
{"pmid": "4370274", "title": "Potential antitumor agents. 10. Synthesis and biochemical properties of 5-N-alkylamino-,N,N-dialkylamino-, and N-alkylacetamido-1-formylisoquinoline thiosemicarbazones.", "content": "Potential antitumor agents. 10. Synthesis and biochemical properties of 5-N-alkylamino-,N,N-dialkylamino-, and N-alkylacetamido-1-formylisoquinoline thiosemicarbazones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370274"}
{"pmid": "4370275", "title": "Potential antitumor agents. 11. Inhibitors of alkaline phosphatase, an enzyme involved in the resistance of neoplastic cells to 6-thiopurines.", "content": "Potential antitumor agents. 11. Inhibitors of alkaline phosphatase, an enzyme involved in the resistance of neoplastic cells to 6-thiopurines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370275"}
{"pmid": "4370276", "title": "Power spectral density of hippocampal theta activity during rhombencephalic sleep, after physostigmine administration and during orienting reaction.", "content": "Power spectral density of hippocampal theta activity during rhombencephalic sleep, after physostigmine administration and during orienting reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370276"}
{"pmid": "4370277", "title": "Preparation of microcells by enucleation of micronucleate cells.", "content": "Preparation of microcells by enucleation of micronucleate cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370277"}
{"pmid": "4370279", "title": "Presence of two active X chromosomes in hybrids between normal human and SV40-transformed fibroblasts from patients with the Lesch-Nyhan syndrome.", "content": "Presence of two active X chromosomes in hybrids between normal human and SV40-transformed fibroblasts from patients with the Lesch-Nyhan syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370279"}
{"pmid": "4370278", "title": "Presence of repeating sub-sequences and symmetry patterns in proteins.", "content": "Presence of repeating sub-sequences and symmetry patterns in proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370278"}
{"pmid": "4370280", "title": "Presynaptic inhibition: primary afferent depolarization in crayfish neurons.", "content": "Presynaptic inhibition: primary afferent depolarization in crayfish neurons. Inhibition of transmission between tactile sensory neurons and interneurons in the crayfish was investigated by intracellular recording int the presynaptic processes. Inhibition is correlated with a depolarization of the presynaptic process, as in the mammalian spinal cord; the depolarization is accompanied by a conductance increase, and is mediated by interneurons that can be excited by a variety of routes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370280"}
{"pmid": "4370282", "title": "Prevention and treatment; a stategy for survival.", "content": "Prevention and treatment; a stategy for survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370282"}
{"pmid": "4370283", "title": "Preventive maintenance for mentally ill patients.", "content": "Preventive maintenance for mentally ill patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370283"}
{"pmid": "4370286", "title": "Problem solving: waking and dreaming.", "content": "Problem solving: waking and dreaming.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370286"}
{"pmid": "4370284", "title": "Primary breast and lung carcinoma in the same patient.", "content": "Primary breast and lung carcinoma in the same patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370284"}
{"pmid": "4370285", "title": "Primary type V hyperlipoproteinaemia (mixed hyperlipaemia): successful response to dietary restriction and simfibrate.", "content": "Primary type V hyperlipoproteinaemia (mixed hyperlipaemia): successful response to dietary restriction and simfibrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370285"}
{"pmid": "4370287", "title": "Proceedings: A possible origin of the 'giant' spontaneous potentials that occur after prolonged transmitter release at frog neuromuscular junctions.", "content": "Proceedings: A possible origin of the 'giant' spontaneous potentials that occur after prolonged transmitter release at frog neuromuscular junctions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370287"}
{"pmid": "4370289", "title": "Proceedings: Benign tumours of the kidney in infancy.", "content": "Proceedings: Benign tumours of the kidney in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370289"}
{"pmid": "4370288", "title": "Proceedings: Azurophil and specific granules of blood neutrophils in chronic myelogenous leukaemia: and ultrastructural and cytochemical analysis.", "content": "Proceedings: Azurophil and specific granules of blood neutrophils in chronic myelogenous leukaemia: and ultrastructural and cytochemical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370288"}
{"pmid": "4370290", "title": "Procollagen: intermediate forms containing several types of peptide chains and non-collagen peptide extensions at NH2 and COOH ends.", "content": "Procollagen: intermediate forms containing several types of peptide chains and non-collagen peptide extensions at NH2 and COOH ends. A population of procollagen molecules has been isolated from the culture medium of a clonal line of calf dermatosparactic cells and shown to have the amino-acid composition, physical properties, and molecular structure consistent with collagen precursors. Although this procollagen population shares immunologic determinants with the procollagen obtained from dermatosparactic skin, it differs from the latter in aminoacid composition, in subunit properties, and by its content of both amino and carboxyl terminal non-collagen peptide appendages. We propose that the cell culture procollagen contains earlier biosynthetic forms of dermatosparactic procollagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370290"}
{"pmid": "4370292", "title": "Prolactin release in cattle.", "content": "Prolactin release in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370292"}
{"pmid": "4370281", "title": "Prevalence of asymptomatic femoral artery atheromas in hyperlipoproteinemic patients.", "content": "Prevalence of asymptomatic femoral artery atheromas in hyperlipoproteinemic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370281"}
{"pmid": "4370291", "title": "Progesterone receptors of chick oviduct. Steroid-binding \"subunit\" formed with divalent cations.", "content": "Progesterone receptors of chick oviduct. Steroid-binding \"subunit\" formed with divalent cations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370291"}
{"pmid": "4370293", "title": "Propagation of mouse cytomegalovirus in murine renal epithelium.", "content": "Propagation of mouse cytomegalovirus in murine renal epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370293"}
{"pmid": "4370294", "title": "Properties of enucleated cells. II. Characteristic overlapping of transformed cells is reestablished by enucleates.", "content": "Properties of enucleated cells. II. Characteristic overlapping of transformed cells is reestablished by enucleates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370294"}
{"pmid": "4370296", "title": "Prostaglandin inhibition of cyclic-AMP accumulation and rate of lipolysis in fat cells.", "content": "Prostaglandin inhibition of cyclic-AMP accumulation and rate of lipolysis in fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370296"}
{"pmid": "4370295", "title": "Properties of the specific binding of 125I-nerve growth factor to responsive peripheral neurons.", "content": "Properties of the specific binding of 125I-nerve growth factor to responsive peripheral neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370295"}
{"pmid": "4370297", "title": "Prostaglandin synthesis in rabbit graafian follicles in vitro. Effect of luteinizing hormone and cyclic AMP.", "content": "Prostaglandin synthesis in rabbit graafian follicles in vitro. Effect of luteinizing hormone and cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370297"}
{"pmid": "4370298", "title": "Prostaglandin F production in vitro by granulosa cells from rabbit pre-ovulatory follicles.", "content": "Prostaglandin F production in vitro by granulosa cells from rabbit pre-ovulatory follicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370298"}
{"pmid": "4370299", "title": "Prostaglandin 15-hydroxy dehydrogenase and delta13 reductase levels in the lungs of maternal, fetal and neonatal rabbits.", "content": "Prostaglandin 15-hydroxy dehydrogenase and delta13 reductase levels in the lungs of maternal, fetal and neonatal rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370299"}
{"pmid": "4370301", "title": "Proton equilibria and kinetics in the liver alcohol dehydrogenase reaction mechanism.", "content": "Proton equilibria and kinetics in the liver alcohol dehydrogenase reaction mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370301"}
{"pmid": "4370300", "title": "Protein metabolism in hypertrophied heart muscle.", "content": "Protein metabolism in hypertrophied heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370300"}
{"pmid": "4370304", "title": "Purification of a ribonuclease inhibitor from Novikoff hepatoma supernatant fraction.", "content": "Purification of a ribonuclease inhibitor from Novikoff hepatoma supernatant fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370304"}
{"pmid": "4370302", "title": "Pseudohypoparathyroidism type II: restoration of normal renal responsiveness to parathyroid hormone by calcium administration.", "content": "Pseudohypoparathyroidism type II: restoration of normal renal responsiveness to parathyroid hormone by calcium administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370302"}
{"pmid": "4370303", "title": "Purification and characterization of anti-A agglutinin from Euhadra callizoma amaliae.", "content": "Purification and characterization of anti-A agglutinin from Euhadra callizoma amaliae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370303"}
{"pmid": "4370305", "title": "Pyruvate oxidation in neuromuscular diseases. Evidence of a genetic defect in two families with the clinical syndrome of Friedreich's ataxia.", "content": "Pyruvate oxidation in neuromuscular diseases. Evidence of a genetic defect in two families with the clinical syndrome of Friedreich's ataxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370305"}
{"pmid": "4370306", "title": "PGF-2 alpha-induced loss of corpus luteum gonadotrophin receptors.", "content": "PGF-2 alpha-induced loss of corpus luteum gonadotrophin receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370306"}
{"pmid": "4370308", "title": "Radiation effects and adrenal cortex. VII. Corticosteroid changes in mice following whole-body irradiation.", "content": "Radiation effects and adrenal cortex. VII. Corticosteroid changes in mice following whole-body irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370308"}
{"pmid": "4370309", "title": "Radioimmunoassay of the major group specific protein of endogenous baboon type C viruses: relation to the RD-114-CCC group and detection of antigen in normal baboon tissues.", "content": "Radioimmunoassay of the major group specific protein of endogenous baboon type C viruses: relation to the RD-114-CCC group and detection of antigen in normal baboon tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370309"}
{"pmid": "4370307", "title": "Quantitative studies of the inhibitory effect of perchlorate on the concentration of 36C1O minus 4 125I minus and 99mTcO minus 4 in salivary glands of male and female mice.", "content": "Quantitative studies of the inhibitory effect of perchlorate on the concentration of 36C1O minus 4 125I minus and 99mTcO minus 4 in salivary glands of male and female mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370307"}
{"pmid": "4370310", "title": "Rapid estimation of small amounts of formaldehyde liberated during periodate oxidation of a sialoglycoprotein.", "content": "Rapid estimation of small amounts of formaldehyde liberated during periodate oxidation of a sialoglycoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370310"}
{"pmid": "4370311", "title": "Rapid separation of tumor-promoting agents, phorbol and phorbol myristate acetate (12-o-tetradecanoylphorbol-13-acetate) by high-pressure liquid chromatography.", "content": "Rapid separation of tumor-promoting agents, phorbol and phorbol myristate acetate (12-o-tetradecanoylphorbol-13-acetate) by high-pressure liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370311"}
{"pmid": "4370312", "title": "Rates of disappearance from blood and biological potencies of mammalian gonadotropins (HCG and ovine LH) in the toad Bufo bufo bufo (L.).", "content": "Rates of disappearance from blood and biological potencies of mammalian gonadotropins (HCG and ovine LH) in the toad Bufo bufo bufo (L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370312"}
{"pmid": "4370313", "title": "Reaction center bacteriochlorophyll triplet states: redox potential dependence and kinetics.", "content": "Reaction center bacteriochlorophyll triplet states: redox potential dependence and kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370313"}
{"pmid": "4370314", "title": "Recent work on virus diseases.", "content": "Recent work on virus diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370314"}
{"pmid": "4370315", "title": "Receptive fields and response properties of mechanoreceptor neurons innervating siphon skin and mantle shelf in Aplysia.", "content": "Receptive fields and response properties of mechanoreceptor neurons innervating siphon skin and mantle shelf in Aplysia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370315"}
{"pmid": "4370316", "title": "Recognition of TMV RNA by the tRNA nucleotidyltransferase.", "content": "Recognition of TMV RNA by the tRNA nucleotidyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370316"}
{"pmid": "4370318", "title": "Recurrent idiopathic polyneuropathy.", "content": "Recurrent idiopathic polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370318"}
{"pmid": "4370317", "title": "Reconstituted hamster liver microsomal enzyme system for N-hydroxylation of the carcinogen 2-acetylaminofluorene.", "content": "Reconstituted hamster liver microsomal enzyme system for N-hydroxylation of the carcinogen 2-acetylaminofluorene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370317"}
{"pmid": "4370319", "title": "Recurrent paroxysmal nonepileptic disorders.", "content": "Recurrent paroxysmal nonepileptic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370319"}
{"pmid": "4370320", "title": "Red chorda tympani nerve and Bell's palsy.", "content": "Red chorda tympani nerve and Bell's palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370320"}
{"pmid": "4370322", "title": "Reduction of ferricytochrome c by hydrogen atoms: evidence for intramolecular transfer of reducing equivalent.", "content": "Reduction of ferricytochrome c by hydrogen atoms: evidence for intramolecular transfer of reducing equivalent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370322"}
{"pmid": "4370321", "title": "Reduced aldosterone secretion during spironolactone treatment in primary aldosteronism: report of a case.", "content": "Reduced aldosterone secretion during spironolactone treatment in primary aldosteronism: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370321"}
{"pmid": "4370324", "title": "Regional diversity in excitatory and inhibitory receptive-field organization of cat thalamic ventrobasal neurons.", "content": "Regional diversity in excitatory and inhibitory receptive-field organization of cat thalamic ventrobasal neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370324"}
{"pmid": "4370325", "title": "Regulation of protein phosphorylation and membrane permeability by beta-adrenergic agents and cyclic adenosine 3':5'-monophosphate in the avian erythrocyte.", "content": "Regulation of protein phosphorylation and membrane permeability by beta-adrenergic agents and cyclic adenosine 3':5'-monophosphate in the avian erythrocyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370325"}
{"pmid": "4370327", "title": "Rejection of mammary adenocarcinoma cell tumors and the prevention of progressive growth of incipient metastases following intratumor permeation with killed Bordetella pertussis.", "content": "Rejection of mammary adenocarcinoma cell tumors and the prevention of progressive growth of incipient metastases following intratumor permeation with killed Bordetella pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370327"}
{"pmid": "4370326", "title": "Regulation of renal circulation during behavioral changes in the cat.", "content": "Regulation of renal circulation during behavioral changes in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370326"}
{"pmid": "4370328", "title": "Relation between rhythmical hippocampal (\"theta\") and olfactory (breath) EEG activity during spontaneous behaviour and REM sleep in rats.", "content": "Relation between rhythmical hippocampal (\"theta\") and olfactory (breath) EEG activity during spontaneous behaviour and REM sleep in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370328"}
{"pmid": "4370329", "title": "Relationship of calcium uptake and calcium-binding protein synthesis in chick and rat intestine in response to Solanum malacoxylon.", "content": "Relationship of calcium uptake and calcium-binding protein synthesis in chick and rat intestine in response to Solanum malacoxylon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370329"}
{"pmid": "4370330", "title": "Relationship of glucose metabolism to adrenergic transmission in rat mesenteric arteries. Effects of glucose deprivation, glucose metabolites, and changes in ionic composition on adrenergic mechanisms.", "content": "Relationship of glucose metabolism to adrenergic transmission in rat mesenteric arteries. Effects of glucose deprivation, glucose metabolites, and changes in ionic composition on adrenergic mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370330"}
{"pmid": "4370331", "title": "Release of kallikrein from isolated cellular organelles of the rat submandibular salivary gland.", "content": "Release of kallikrein from isolated cellular organelles of the rat submandibular salivary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370331"}
{"pmid": "4370332", "title": "Renal neoplasms in children.", "content": "Renal neoplasms in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370332"}
{"pmid": "4370333", "title": "Renin release by rat kidney slices in vitro: effects of cations and catecholamines.", "content": "Renin release by rat kidney slices in vitro: effects of cations and catecholamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370333"}
{"pmid": "4370334", "title": "Reo-like neonatal calf diarrhoea (NCD) virus demonstrated in Denmark.", "content": "Reo-like neonatal calf diarrhoea (NCD) virus demonstrated in Denmark.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370334"}
{"pmid": "4370335", "title": "Repetitive patterns of metabolic changes during cortical spreading depression of the awake rat.", "content": "Repetitive patterns of metabolic changes during cortical spreading depression of the awake rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370335"}
{"pmid": "4370336", "title": "Replication of arboviruses in mouse organ cultures. I. Results with Middelburg virus in organ cultures and peritoneal macrophages.", "content": "Replication of arboviruses in mouse organ cultures. I. Results with Middelburg virus in organ cultures and peritoneal macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370336"}
{"pmid": "4370323", "title": "Reduction of serum triglyceride levels by polyunsaturated fat. Studies on the mode of action and on very low density lipoprotein composition.", "content": "Reduction of serum triglyceride levels by polyunsaturated fat. Studies on the mode of action and on very low density lipoprotein composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370323"}
{"pmid": "4370338", "title": "Representation of the course of an outbreak of contagious bovine pleuro-pneumonia in a sedentary herd of humpless cattle.", "content": "Representation of the course of an outbreak of contagious bovine pleuro-pneumonia in a sedentary herd of humpless cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370338"}
{"pmid": "4370337", "title": "Report from Sloan-Kettering Institute. Enzyme therapy and nutritional depletion of tumors.", "content": "Report from Sloan-Kettering Institute. Enzyme therapy and nutritional depletion of tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370337"}
{"pmid": "4370340", "title": "Requirement of 3'-terminal poly(adenylic acid) for the infectivity of poliovirus RNA.", "content": "Requirement of 3'-terminal poly(adenylic acid) for the infectivity of poliovirus RNA. Ribonuclease H (EC 3.1.4.34) has been used to remove selectively much of the 3'-terminal poly(adenylic acid) [poly(A)] from poliovirus RNA by treating the RNA with the enzyme in the presence of poly(dT). Over 80% of the poly(A) could be removed and the residuum was found as oligo(A) stretches attached to many or all of the viral RNA molecules. Reduction of the size of the poly(A) markedly decreased the specific infectivity of poliovirus RNA, indicating that poly(A) is necessary to the infectivity of the RNA. The virions in plaques deriving from infection with treated RNA have a normal amount and size of poly(A), indicating that mechanisms exist in infected cells to regenerate normal length poly(A) from truncated poly(A).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370340"}
{"pmid": "4370341", "title": "Reserve of vasopressin-sensitive adenylate cyclase in toad urinary bladder.", "content": "Reserve of vasopressin-sensitive adenylate cyclase in toad urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370341"}
{"pmid": "4370339", "title": "Requirement for double-stranded RNA during the in vitro synthesis of RNA by foot-and-mouth disease virus replicase.", "content": "Requirement for double-stranded RNA during the in vitro synthesis of RNA by foot-and-mouth disease virus replicase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370339"}
{"pmid": "4370342", "title": "Residential facilities for hospital-discharged former mental patients. Aspects in development.", "content": "Residential facilities for hospital-discharged former mental patients. Aspects in development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370342"}
{"pmid": "4370343", "title": "Response of chick-embryo kidney cells in vitro to two avian tumor viruses.", "content": "Response of chick-embryo kidney cells in vitro to two avian tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370343"}
{"pmid": "4370345", "title": "Rheumatic manifestations of hypophosphatemia.", "content": "Rheumatic manifestations of hypophosphatemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370345"}
{"pmid": "4370347", "title": "Ribonucleotides in newly synthesized DNA of herpes simplex virus.", "content": "Ribonucleotides in newly synthesized DNA of herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370347"}
{"pmid": "4370346", "title": "Riboflavin metabolism in cancer.", "content": "Riboflavin metabolism in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370346"}
{"pmid": "4370348", "title": "Rifamycin derivatives as inhibitors of a ribonucleic acid instructed deoxyribonucleic acid polymerase function. Effect of lipophilicity.", "content": "Rifamycin derivatives as inhibitors of a ribonucleic acid instructed deoxyribonucleic acid polymerase function. Effect of lipophilicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370348"}
{"pmid": "4370350", "title": "Role of enzyme interactions in the regulation of gluconeogenesis. Modification of the binding properties of fructose 1,6-diphosphatase by adenosine monophosphate, adenosine triphosphate, and fructose 1,6-diphosphate.", "content": "Role of enzyme interactions in the regulation of gluconeogenesis. Modification of the binding properties of fructose 1,6-diphosphatase by adenosine monophosphate, adenosine triphosphate, and fructose 1,6-diphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370350"}
{"pmid": "4370349", "title": "Role of deoxyribonucleic acid-ribonucleic acid hybrids in eukaryotes. Study of the template requirements of yeast ribonucleic acid polymerases and nature of the ribonucleic acid product.", "content": "Role of deoxyribonucleic acid-ribonucleic acid hybrids in eukaryotes. Study of the template requirements of yeast ribonucleic acid polymerases and nature of the ribonucleic acid product.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370349"}
{"pmid": "4370351", "title": "Rotator cuff tear versus suprascapular nerve injury: a problem in differential diagnosis.", "content": "Rotator cuff tear versus suprascapular nerve injury: a problem in differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370351"}
{"pmid": "4370352", "title": "Schistosomatium douthitti: effects of thyroxine.", "content": "Schistosomatium douthitti: effects of thyroxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370352"}
{"pmid": "4370353", "title": "Screening and genetic counseling programs for sickle cell trait and sickle cell anemia.", "content": "Screening and genetic counseling programs for sickle cell trait and sickle cell anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370353"}
{"pmid": "4370354", "title": "Screening tests for renovascular hypertension--an appraisal.", "content": "Screening tests for renovascular hypertension--an appraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370354"}
{"pmid": "4370356", "title": "Selection of hormone-dependent breast cancers.", "content": "Selection of hormone-dependent breast cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370356"}
{"pmid": "4370357", "title": "Selective inhibition of the synthesis of single-stranded RNA of encephalomyocarditis virus by 2-(alpha-hydroxybenzyl)-benzimidazole in cell-free systems.", "content": "Selective inhibition of the synthesis of single-stranded RNA of encephalomyocarditis virus by 2-(alpha-hydroxybenzyl)-benzimidazole in cell-free systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370357"}
{"pmid": "4370355", "title": "Secretion rates and chemical composition of oviduct and uterine fluids in sows.", "content": "Secretion rates and chemical composition of oviduct and uterine fluids in sows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370355"}
{"pmid": "4370344", "title": "Responses of resistance and capacitance vessels in feline nasal mucosa to vasoactive agents.", "content": "Responses of resistance and capacitance vessels in feline nasal mucosa to vasoactive agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370344"}
{"pmid": "4370358", "title": "Selective thymic localization of murine leukemia virus-related antigens in C57BL-Ka mice after inoculation with radiation virus.", "content": "Selective thymic localization of murine leukemia virus-related antigens in C57BL-Ka mice after inoculation with radiation virus. The tissue distribution and extent of virus-specific antigen expression were studied by immunofluorescence as a function of time and of lymphoma development in adult C57BL/Ka (Fv-1(b)) mice after intravenous injection of radiation leukemia virus, a B-tropic murine leukemia virus. Viral antigens were detected earlier in the thymus (1 week) than in the bone marrow, spleen, or lymph nodes (2-3 weeks). Despite an initial virus-induced thymic involution, the percentage of immunofluorescence-positive cells in the thymus rapidly increased thereafter to 65-80%, at which level it remained until 9 weeks, at which time increases in size and weight, histological changes, and an increased number of blastoid cells indicated the onset of lymphoma development in the thymus. In contrast, the percentage of immunofluorescence-positive cells in the bone marrow, spleen, and nodes remained low, and gradually decreased to zero within 8 weeks after thymectomy. The selective thymic localization of antigens induced by radiation leukemia virus in C57BL/Ka mice is in striking contrast to the previously reported ubiquitous tissue distribution of the Gross-AKR virus, an N-tropic virus, in its natural host, the Fv-1(n), AKR strain with a high incidence of leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370358"}
{"pmid": "4370359", "title": "Sensation and sensibility in the upper extremity.", "content": "Sensation and sensibility in the upper extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370359"}
{"pmid": "4370360", "title": "Sensitivity of target cells to the cytotoxic effects of lymphocytes induced by interferon.", "content": "Sensitivity of target cells to the cytotoxic effects of lymphocytes induced by interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370360"}
{"pmid": "4370361", "title": "Sensory transmission through lemniscal pathway during voluntary movement in the cat.", "content": "Sensory transmission through lemniscal pathway during voluntary movement in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370361"}
{"pmid": "4370362", "title": "Separation of amino acids from untreated urine on thin layers of silica gel.", "content": "Separation of amino acids from untreated urine on thin layers of silica gel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370362"}
{"pmid": "4370363", "title": "Separation of newly synthesized nucleohistone by equilibrium centrifugation in cesium chloride.", "content": "Separation of newly synthesized nucleohistone by equilibrium centrifugation in cesium chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370363"}
{"pmid": "4370364", "title": "Septal hyperdipsia: specific enhancement of drinking to angiotensin in rats.", "content": "Septal hyperdipsia: specific enhancement of drinking to angiotensin in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370364"}
{"pmid": "4370365", "title": "Serological examination of a sample of human population and some animal species for the presence of antibodies to Yaba 1 virus.", "content": "Serological examination of a sample of human population and some animal species for the presence of antibodies to Yaba 1 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370365"}
{"pmid": "4370366", "title": "Serum and tissue lipid metabolism and effect of nicotinic acid in different types of hyperlipidemia.", "content": "Serum and tissue lipid metabolism and effect of nicotinic acid in different types of hyperlipidemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370366"}
{"pmid": "4370367", "title": "Serum lipoprotein abnormalities in patients with ischaemic heart disease: comparisons with a control population.", "content": "Serum lipoprotein abnormalities in patients with ischaemic heart disease: comparisons with a control population. The frequency and nature of abnormalities of serum lipoproteins have been studied, using quantitative techniques, in 143 patients with ischaemic heart disease (I.H.D.). Rigorous selection criteria were used. The findings were related to the distribution of lipoprotein concentrations in a carefully screened control population. Hyperlipoproteinaemia occurred in 55% of patients and in 11 out of 15 patients aged less than 40 years. Raised triglyceride and cholesterol concentrations in very low density lipoprotein were the most frequent abnormalities followed by raised cholesterol content of low density lipoprotein. In young patients high density lipoprotein levels were subnormal. Hyperlipoproteinaemia of W.H.O. types IIa, IIb, III, IV, and V all seemed to be over-represented in I.H.D. I.H.D. patients with type IIa, IIb, and IV abnormalities were all significantly younger than I.H.D. patients with normal lipoprotein levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370367"}
{"pmid": "4370369", "title": "Short length amino acid sequence homology among ancestrally unrelated proteins.", "content": "Short length amino acid sequence homology among ancestrally unrelated proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370369"}
{"pmid": "4370368", "title": "Serum lipoproteins and coronary heart disease.", "content": "Serum lipoproteins and coronary heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370368"}
{"pmid": "4370371", "title": "Similar effects of calitonin, insulin and somatomedin A on lipolysis and uptake of calcium and glucose in rat adipose tissue in vitro.", "content": "Similar effects of calitonin, insulin and somatomedin A on lipolysis and uptake of calcium and glucose in rat adipose tissue in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370371"}
{"pmid": "4370370", "title": "Sialyl transferase activities of rat ascites hepatoma cells and rat liver.", "content": "Sialyl transferase activities of rat ascites hepatoma cells and rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370370"}
{"pmid": "4370374", "title": "Skeletal maturation of the hand and wrist of young children in Baghdad.", "content": "Skeletal maturation of the hand and wrist of young children in Baghdad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370374"}
{"pmid": "4370373", "title": "Simultaneous stimulation test for the anterior pituitary hormones.", "content": "Simultaneous stimulation test for the anterior pituitary hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370373"}
{"pmid": "4370372", "title": "Simultaneous evaluation of the pituitary reserve of GH, TSH, ACTH and LH in children.", "content": "Simultaneous evaluation of the pituitary reserve of GH, TSH, ACTH and LH in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370372"}
{"pmid": "4370375", "title": "Sleep of depressed patients in remission.", "content": "Sleep of depressed patients in remission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370375"}
{"pmid": "4370376", "title": "Sleep-associated growth hormone (GH) release in schizophrenia.", "content": "Sleep-associated growth hormone (GH) release in schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370376"}
{"pmid": "4370378", "title": "Society pays for the learning disabled.", "content": "Society pays for the learning disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370378"}
{"pmid": "4370377", "title": "Slow evolution of transferrin and albumin in birds according to micro-complement fixation analysis.", "content": "Slow evolution of transferrin and albumin in birds according to micro-complement fixation analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370377"}
{"pmid": "4370379", "title": "Solvent isotope effects on the structure and function of mitochondrial membranes in aqueous media.", "content": "Solvent isotope effects on the structure and function of mitochondrial membranes in aqueous media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370379"}
{"pmid": "4370380", "title": "Some chemical and stereochemical modifications of the erythromycin lactone rings.", "content": "Some chemical and stereochemical modifications of the erythromycin lactone rings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370380"}
{"pmid": "4370381", "title": "Some in vivo interactions of oestradiol with the mouse vagina.", "content": "Some in vivo interactions of oestradiol with the mouse vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370381"}
{"pmid": "4370382", "title": "Some peculiarities of metabolism of the myocardium under conditions of experimental disturbance of the microcirculation.", "content": "Some peculiarities of metabolism of the myocardium under conditions of experimental disturbance of the microcirculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370382"}
{"pmid": "4370384", "title": "Specific binding of 8-anilinonaphthalene sulfonate to diphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart.", "content": "Specific binding of 8-anilinonaphthalene sulfonate to diphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370384"}
{"pmid": "4370385", "title": "Specificity of ribonucleic acid chain initiation by bacteriophage T3-induced ribonucleic acid polymerase.", "content": "Specificity of ribonucleic acid chain initiation by bacteriophage T3-induced ribonucleic acid polymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370385"}
{"pmid": "4370386", "title": "Spectral characterization of 15N spin labels.", "content": "Spectral characterization of 15N spin labels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370386"}
{"pmid": "4370387", "title": "Spinal and supraspinal factors in the control of voluntary activity under normal and pathological conditions.", "content": "Spinal and supraspinal factors in the control of voluntary activity under normal and pathological conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370387"}
{"pmid": "4370388", "title": "Statistical quality control and routine data processing for radioimmunoassays and immunoradiometric assays.", "content": "Statistical quality control and routine data processing for radioimmunoassays and immunoradiometric assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370388"}
{"pmid": "4370389", "title": "Stereotactic Curie-therapy of pituitary adenomas. A long-term follow-up study.", "content": "Stereotactic Curie-therapy of pituitary adenomas. A long-term follow-up study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370389"}
{"pmid": "4370390", "title": "Steroid hormones and breast cancer.", "content": "Steroid hormones and breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370390"}
{"pmid": "4370383", "title": "Some recent advances in virilizing and feminizing syndromes and hirsutism.", "content": "Some recent advances in virilizing and feminizing syndromes and hirsutism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370383"}
{"pmid": "4370391", "title": "Stimulated formation of cyclic adenosine 3':5'-monophosphate by aspartate and glutamate in cerebral cortical slices of guinea pig.", "content": "Stimulated formation of cyclic adenosine 3':5'-monophosphate by aspartate and glutamate in cerebral cortical slices of guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370391"}
{"pmid": "4370392", "title": "Stimulation of the synthesis of very low density lipoproteins in rooster liver by estradiol.", "content": "Stimulation of the synthesis of very low density lipoproteins in rooster liver by estradiol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370392"}
{"pmid": "4370394", "title": "Stochastic models for single neuron firing trains: a survey.", "content": "Stochastic models for single neuron firing trains: a survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370394"}
{"pmid": "4370393", "title": "Stimulation of vascular smooth muscle sodium, potassium--adenosinetriphosphatase by vasodilators.", "content": "Stimulation of vascular smooth muscle sodium, potassium--adenosinetriphosphatase by vasodilators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370393"}
{"pmid": "4370395", "title": "Stress and the hormonal regulation of the immune response in mice.", "content": "Stress and the hormonal regulation of the immune response in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370395"}
{"pmid": "4370396", "title": "Stress, insulin antagonist and transient diabetes mellitus in the rat.", "content": "Stress, insulin antagonist and transient diabetes mellitus in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370396"}
{"pmid": "4370397", "title": "Structural investigation of oxalate-soluble rapeseed (Brassica campestris) polysaccharides. 3. An arabinan.", "content": "Structural investigation of oxalate-soluble rapeseed (Brassica campestris) polysaccharides. 3. An arabinan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370397"}
{"pmid": "4370399", "title": "Studies on an extracellular coat of mammalian sperm with reference to its DNA content.", "content": "Studies on an extracellular coat of mammalian sperm with reference to its DNA content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370399"}
{"pmid": "4370398", "title": "Structure of yeast hexokinase. 3. Low resolution structure of a second crystal form showing a different quaternary structure, heterologous interaction of subunits and substrate binding.", "content": "Structure of yeast hexokinase. 3. Low resolution structure of a second crystal form showing a different quaternary structure, heterologous interaction of subunits and substrate binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370398"}
{"pmid": "4370400", "title": "Studies on feline lymphosarcoma in the Sydney area.", "content": "Studies on feline lymphosarcoma in the Sydney area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370400"}
{"pmid": "4370401", "title": "Studies on lipid and fatty acid composition of human hepatoma tissue.", "content": "Studies on lipid and fatty acid composition of human hepatoma tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370401"}
{"pmid": "4370403", "title": "Studies on the conformational changes of metalloproteins induced by electrons in water-ethylene glycol solutions at low temperatures. Cytochrome C.", "content": "Studies on the conformational changes of metalloproteins induced by electrons in water-ethylene glycol solutions at low temperatures. Cytochrome C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370403"}
{"pmid": "4370402", "title": "Studies on the angiotensin II receptor in the zona glomerulosa of the rat adrenal gland.", "content": "Studies on the angiotensin II receptor in the zona glomerulosa of the rat adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370402"}
{"pmid": "4370404", "title": "Studies on the differential response to glucagon concentration on gluconeogenesis in isolated hepatocytes containing high and low glycogen.", "content": "Studies on the differential response to glucagon concentration on gluconeogenesis in isolated hepatocytes containing high and low glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370404"}
{"pmid": "4370406", "title": "Studies on the metabolism of ATP by isolated bacterial membranes: role of succinyl CoA synthetase in diglyceride kinase activity.", "content": "Studies on the metabolism of ATP by isolated bacterial membranes: role of succinyl CoA synthetase in diglyceride kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370406"}
{"pmid": "4370405", "title": "Studies on the mechanism of action of udp-D-glucose dehydrogenase from beef liver. II.", "content": "Studies on the mechanism of action of udp-D-glucose dehydrogenase from beef liver. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370405"}
{"pmid": "4370407", "title": "Studies on vitamin D and its analogs. I. Synthesis of 1alpha-hydroxycholest-5-ene.", "content": "Studies on vitamin D and its analogs. I. Synthesis of 1alpha-hydroxycholest-5-ene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370407"}
{"pmid": "4370408", "title": "Study of enterovirus replication in human tissue explants, using photosensitized virus strains.", "content": "Study of enterovirus replication in human tissue explants, using photosensitized virus strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370408"}
{"pmid": "4370409", "title": "Study of the oxygen effect mediated by Janus green B.", "content": "Study of the oxygen effect mediated by Janus green B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370409"}
{"pmid": "4370410", "title": "Subcellular distribution of oxidative enzymes in human, inflamed and dilantin hyperplastic gingiva.", "content": "Subcellular distribution of oxidative enzymes in human, inflamed and dilantin hyperplastic gingiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370410"}
{"pmid": "4370411", "title": "Subcellular localization of ribonucleotide reductase in Novikoff hepatoma and regenerating rat liver.", "content": "Subcellular localization of ribonucleotide reductase in Novikoff hepatoma and regenerating rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370411"}
{"pmid": "4370412", "title": "Subclinical congenital cytomegalovirus infection and hearing impairment.", "content": "Subclinical congenital cytomegalovirus infection and hearing impairment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370412"}
{"pmid": "4370413", "title": "Subcutaneous adipose tissue and lipids in blood in growth hormone deficiency before and after treatment with human growth hormone.", "content": "Subcutaneous adipose tissue and lipids in blood in growth hormone deficiency before and after treatment with human growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370413"}
{"pmid": "4370415", "title": "Succinate dehydrogenase and cytochrome oxidase in adult and plerocercoid Diphyllobothrium latum.", "content": "Succinate dehydrogenase and cytochrome oxidase in adult and plerocercoid Diphyllobothrium latum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370415"}
{"pmid": "4370414", "title": "Substrate activation and product inhibition of LDH activity in human skeletal muscle.", "content": "Substrate activation and product inhibition of LDH activity in human skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370414"}
{"pmid": "4370416", "title": "Suppression of fibrinolysin T activity fails to restore density-dependent growth inhibition to SV3T3 cells.", "content": "Suppression of fibrinolysin T activity fails to restore density-dependent growth inhibition to SV3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370416"}
{"pmid": "4370417", "title": "Surgery of the pterygoid fossa.", "content": "Surgery of the pterygoid fossa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370417"}
{"pmid": "4370418", "title": "Survival and growth in a woman with untreated hypothalamic panhypopituitarism of 21 years' duration.", "content": "Survival and growth in a woman with untreated hypothalamic panhypopituitarism of 21 years' duration. A 29-year-old woman with evidence of a craniopharyngioma and documented panhypopituitarism is described. Clinical and laboratory evaluation revealed deficiencies of follicle-stimulating hormone, luteinizing hormone, thyroid-stimulating hormone, growth hormone, prolactin, adrenocorticotropic hormone and antidiuretic hormone. Prompt release of several pituitary hormones was noticed after administration of the hypothalamic releasing hormones FSH/LH-RF and thyrotropin-releasing hormone, whereas insulin-induced hypoglycemia, levodopa, chlorpromazine and clomiphene citrate, all of which act at the level of the hypothalamus, did not alter basal pituitary secretion. The patient's height of 60 inches, despite panhypopituitarism, and the interpretation of the above data are discussed in the light of current concepts regarding the dynamics of the hypothalamic-hypophyseal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370418"}
{"pmid": "4370421", "title": "Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazoles.", "content": "Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370421"}
{"pmid": "4370420", "title": "Synthesis and antimicrobial activity of aliphatic nitro compounds.", "content": "Synthesis and antimicrobial activity of aliphatic nitro compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370420"}
{"pmid": "4370422", "title": "Synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3.", "content": "Synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370422"}
{"pmid": "4370423", "title": "Synthesis and secretion of plasma lipoproteins.", "content": "Synthesis and secretion of plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370423"}
{"pmid": "4370424", "title": "Synthesis of diphosphoinositide by a soluble fraction of Saccharomyces cerevisiae.", "content": "Synthesis of diphosphoinositide by a soluble fraction of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370424"}
{"pmid": "4370425", "title": "Synthesis of viral mRNA and polyadenylate by a ribonucleoprotein complex from extracts of VSV-infected cells.", "content": "Synthesis of viral mRNA and polyadenylate by a ribonucleoprotein complex from extracts of VSV-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370425"}
{"pmid": "4370419", "title": "Sympathetic-parasympathetic interactions on the ventricular myocardium: possible role of cyclic nucleotides.", "content": "Sympathetic-parasympathetic interactions on the ventricular myocardium: possible role of cyclic nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370419"}
{"pmid": "4370426", "title": "Synthesis of 1-(3-deoxy-beta-D-psicofuranosyl)uracil and related compounds.", "content": "Synthesis of 1-(3-deoxy-beta-D-psicofuranosyl)uracil and related compounds. D-Fructose affords on treatment with cyanamide 2-amino-beta-D-fructofuro[2',3':3,4]-oxazoline which is not isolated but transformed directly by the reaction with ethyl propiolate into O(2,3)-anhydro-2-[beta-D-fructofuranosyl]uracil. This compound is benzoylated to the 1',4',6'-tri-O-benzoyl derivative by the action of benzoyl cyanide and triethylamine. On treatment with hydrogen chloride/dimethylformamide, the latter intermediate is converted to the 1-[1,4,6-tri-O-benzoyl-3-chloro-3-deoxy-beta-D-psicofuranosyl]uracil 1',4',5'-tribenzoate from which the title nucleoside derivative is obtained by methanolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370426"}
{"pmid": "4370427", "title": "Temperature effects on the concanavalin A molecule and on concanavalin A binding.", "content": "Temperature effects on the concanavalin A molecule and on concanavalin A binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370427"}
{"pmid": "4370428", "title": "Test and teach number two.", "content": "Test and teach number two.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370428"}
{"pmid": "4370429", "title": "Testing of antiviral compounds against Mengo virus infection of mice. I. Screening of compounds and statistical evaluation of their effects.", "content": "Testing of antiviral compounds against Mengo virus infection of mice. I. Screening of compounds and statistical evaluation of their effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370429"}
{"pmid": "4370430", "title": "The absorption of conjugated oestrogen and sodium oestrone sulphate from the vagina.", "content": "The absorption of conjugated oestrogen and sodium oestrone sulphate from the vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370430"}
{"pmid": "4370431", "title": "The action of phospholipase C and lipase on black film bilayer membranes.", "content": "The action of phospholipase C and lipase on black film bilayer membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370431"}
{"pmid": "4370432", "title": "The adhesion of BHK and PyBHK cells to the substratum.", "content": "The adhesion of BHK and PyBHK cells to the substratum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370432"}
{"pmid": "4370434", "title": "The apolipoproteins.", "content": "The apolipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370434"}
{"pmid": "4370435", "title": "The archaic barbiturate hypnotics.", "content": "The archaic barbiturate hypnotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370435"}
{"pmid": "4370436", "title": "The binding of reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase to hepatic microsomes.", "content": "The binding of reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase to hepatic microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370436"}
{"pmid": "4370438", "title": "The changing attitudes of women: implications for psychotherapy.", "content": "The changing attitudes of women: implications for psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370438"}
{"pmid": "4370437", "title": "The carbohydrate moiety of sea cucumber (Thyone briareus) gelatin.", "content": "The carbohydrate moiety of sea cucumber (Thyone briareus) gelatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370437"}
{"pmid": "4370439", "title": "The clinical and chemical heterogeneity of the beta-thalassemias.", "content": "The clinical and chemical heterogeneity of the beta-thalassemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370439"}
{"pmid": "4370440", "title": "The clinical-chemical application of the NADH test for the determination of diamine oxidase activity in human pregnancy.", "content": "The clinical-chemical application of the NADH test for the determination of diamine oxidase activity in human pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370440"}
{"pmid": "4370442", "title": "The denervated heart. A model for studying autonomic control of the heart.", "content": "The denervated heart. A model for studying autonomic control of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370442"}
{"pmid": "4370441", "title": "The degradation of ribonucleic acids injected into Xenopus laevis oocytes.", "content": "The degradation of ribonucleic acids injected into Xenopus laevis oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370441"}
{"pmid": "4370443", "title": "The detection of hyaluronidase on electrophoresis membranes.", "content": "The detection of hyaluronidase on electrophoresis membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370443"}
{"pmid": "4370444", "title": "The development of nerve-muscle junctions in Rana catesbeiana tadpoles.", "content": "The development of nerve-muscle junctions in Rana catesbeiana tadpoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370444"}
{"pmid": "4370446", "title": "The effect of cyclic 3',5'-adenosine monophosphate on yeast glyceraldehyde-3-phosphate dehydrogenase. II. Initial velocity kinetic studies.", "content": "The effect of cyclic 3',5'-adenosine monophosphate on yeast glyceraldehyde-3-phosphate dehydrogenase. II. Initial velocity kinetic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370446"}
{"pmid": "4370445", "title": "The effect of alpha-tocopherol on cerium induced changes in drug and lipid metabolism of rat.", "content": "The effect of alpha-tocopherol on cerium induced changes in drug and lipid metabolism of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370445"}
{"pmid": "4370447", "title": "The effect of glucagon on adenosine 3',5'-monophosphate (cyclic AMP), glucose, insulin and growth hormone in the full term newborn and children.", "content": "The effect of glucagon on adenosine 3',5'-monophosphate (cyclic AMP), glucose, insulin and growth hormone in the full term newborn and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370447"}
{"pmid": "4370449", "title": "The effect of population density on phenylalanine hydroxylase activity in rat-hepatoma cells in culture.", "content": "The effect of population density on phenylalanine hydroxylase activity in rat-hepatoma cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370449"}
{"pmid": "4370448", "title": "The effect of orally administered cocaine on sleep of depressed patients.", "content": "The effect of orally administered cocaine on sleep of depressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370448"}
{"pmid": "4370450", "title": "The effect of prior inoculation with an enterovirus (LEV 4) on rhinovirus infection of volunteers.", "content": "The effect of prior inoculation with an enterovirus (LEV 4) on rhinovirus infection of volunteers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370450"}
{"pmid": "4370451", "title": "The effect of pH on hycanthone methanesulfonate-induced inactivation and mitotic recombination in saccharomyces.", "content": "The effect of pH on hycanthone methanesulfonate-induced inactivation and mitotic recombination in saccharomyces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370451"}
{"pmid": "4370452", "title": "The effect of synthetic corticotropin analogues on adrenocortical, anterior pituitary and testicular function.", "content": "The effect of synthetic corticotropin analogues on adrenocortical, anterior pituitary and testicular function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370452"}
{"pmid": "4370453", "title": "The effect of Ro 20-1724 upon induced beta-galactosidase synthesis in Escherichia coli.", "content": "The effect of Ro 20-1724 upon induced beta-galactosidase synthesis in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370453"}
{"pmid": "4370454", "title": "The effect of 1-sarcosine, 8-leucyl angiotensin II on the pressor effect of infused angiotensin II.", "content": "The effect of 1-sarcosine, 8-leucyl angiotensin II on the pressor effect of infused angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370454"}
{"pmid": "4370455", "title": "The effects of diet cholesterol on the synthesis of rat serum apolipoproteins.", "content": "The effects of diet cholesterol on the synthesis of rat serum apolipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370455"}
{"pmid": "4370456", "title": "The effects of nicotinamide on mouse sleep.", "content": "The effects of nicotinamide on mouse sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370456"}
{"pmid": "4370457", "title": "The effects of some anti-inflammatory drugs on the acute-phase proteins in rheumatoid arthritis.", "content": "The effects of some anti-inflammatory drugs on the acute-phase proteins in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370457"}
{"pmid": "4370458", "title": "The effects of Lioresal on synaptic activity in the isolated spinal cord.", "content": "The effects of Lioresal on synaptic activity in the isolated spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370458"}
{"pmid": "4370459", "title": "The effects of PGE1 on the spontaneous motility of the guinea pig and rat female reproductive tracts, in vitro.", "content": "The effects of PGE1 on the spontaneous motility of the guinea pig and rat female reproductive tracts, in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370459"}
{"pmid": "4370460", "title": "The establishment of a line of visna virus-producing human astrocytes (V-1181N1).", "content": "The establishment of a line of visna virus-producing human astrocytes (V-1181N1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370460"}
{"pmid": "4370461", "title": "The evolution of ovarian steroid hormones during luteolysis and folliculogenesis in the cow.", "content": "The evolution of ovarian steroid hormones during luteolysis and folliculogenesis in the cow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370461"}
{"pmid": "4370464", "title": "The face in sacred art of the Upper Sepik River of New Guinea: analogies to neuro-developmental aspects and to prosopagnosia. 3. Neuropathologic aspects: prosopagnosia.", "content": "The face in sacred art of the Upper Sepik River of New Guinea: analogies to neuro-developmental aspects and to prosopagnosia. 3. Neuropathologic aspects: prosopagnosia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370464"}
{"pmid": "4370463", "title": "The experimental pathology of cycad toxicity with special reference to oncogenic effects.", "content": "The experimental pathology of cycad toxicity with special reference to oncogenic effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370463"}
{"pmid": "4370465", "title": "The formation of arabino nucleosides from 3-acetamido-1,2-di-O-acetyl-3,5-dideoxy-d-ribofuranose during the fusion synthesis.", "content": "The formation of arabino nucleosides from 3-acetamido-1,2-di-O-acetyl-3,5-dideoxy-d-ribofuranose during the fusion synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370465"}
{"pmid": "4370466", "title": "The fructose 1,6-diphosphatase-phosphofructokinase substrate cycle. A site of regulation of hepatic gluconeogenesis by glucagon.", "content": "The fructose 1,6-diphosphatase-phosphofructokinase substrate cycle. A site of regulation of hepatic gluconeogenesis by glucagon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370466"}
{"pmid": "4370468", "title": "The glomerular basement membrane in long-term allografts with heavy proteinuria.", "content": "The glomerular basement membrane in long-term allografts with heavy proteinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370468"}
{"pmid": "4370469", "title": "The hemicellulose of pollen grains of Phoenix dactylifera.", "content": "The hemicellulose of pollen grains of Phoenix dactylifera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370469"}
{"pmid": "4370470", "title": "The immune response to virally determined tumor associated antigens.", "content": "The immune response to virally determined tumor associated antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370470"}
{"pmid": "4370471", "title": "The importance of DNA size for successful transfection of chicken embryo fibroblasts.", "content": "The importance of DNA size for successful transfection of chicken embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370471"}
{"pmid": "4370473", "title": "The influence of a conscious wish on dreams: a methodological study of dream meaning and function.", "content": "The influence of a conscious wish on dreams: a methodological study of dream meaning and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370473"}
{"pmid": "4370474", "title": "The influence of cholesterol on molecular motion in egg lecithin bilayers--a variable-frequency electron spin resonance study of a cholestane spin probe.", "content": "The influence of cholesterol on molecular motion in egg lecithin bilayers--a variable-frequency electron spin resonance study of a cholestane spin probe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370474"}
{"pmid": "4370472", "title": "The in vitro synthesis of avian myeloblastosis viral RNA sequences.", "content": "The in vitro synthesis of avian myeloblastosis viral RNA sequences. Isolated nuclei, prepared from myeloblasts of chicks infected with avian myeloblastosis virus, synthesize RNA sequences present in avian myeloblastosis viral RNA. These sequences are also formed during transcription of chromatin, isolated from myeloblasts, by DNA-dependent RNA polymerases purified from Escherichia coli or calfthymus. In the latter case, transcription is alpha-amanitin sensitive. Formation of hybrids between RNA and avian myeloblastosis virus DNA probes has been monitored by the combined use of ribonucleases A, T(1), and H, and ribonucleases specific for single strands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370472"}
{"pmid": "4370475", "title": "The influence of supraoptimal temperature on poliovirus type 1 Mahoney strain reproduction.", "content": "The influence of supraoptimal temperature on poliovirus type 1 Mahoney strain reproduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370475"}
{"pmid": "4370476", "title": "The influence of the size of wuartz dust particles on the reaction of lung tissue.", "content": "The influence of the size of wuartz dust particles on the reaction of lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370476"}
{"pmid": "4370467", "title": "The furocoumarin photosensitizing effect on the virus-producing Graffi leukaemia cells.", "content": "The furocoumarin photosensitizing effect on the virus-producing Graffi leukaemia cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370467"}
{"pmid": "4370478", "title": "The interaction of cyclic 3',5'-adenosine monophosphate with yeast glyceraldehyde-3-phosphate dehydrogenase. I. Equilibrium dialysis studies.", "content": "The interaction of cyclic 3',5'-adenosine monophosphate with yeast glyceraldehyde-3-phosphate dehydrogenase. I. Equilibrium dialysis studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370478"}
{"pmid": "4370480", "title": "The isolation and properties of a rabbit liver binding protein specific for asialoglycoproteins.", "content": "The isolation and properties of a rabbit liver binding protein specific for asialoglycoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370480"}
{"pmid": "4370479", "title": "The involvement of human placental microsomal cytochrome P-450 in aromatization.", "content": "The involvement of human placental microsomal cytochrome P-450 in aromatization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370479"}
{"pmid": "4370481", "title": "The isolation of chemically pure elastins in a form suitable for mechanical testing.", "content": "The isolation of chemically pure elastins in a form suitable for mechanical testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370481"}
{"pmid": "4370482", "title": "The isolation of soluble proteins, glycoproteins, and proteoglycans from bone.", "content": "The isolation of soluble proteins, glycoproteins, and proteoglycans from bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370482"}
{"pmid": "4370484", "title": "The mechanism of water-proton relaxation in enzyme paramagnetic-ion complexes. 1. The Gd(3)-lysozyme complex.", "content": "The mechanism of water-proton relaxation in enzyme paramagnetic-ion complexes. 1. The Gd(3)-lysozyme complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370484"}
{"pmid": "4370483", "title": "The isolation of terminally cross-linked DNA and kinetics of venom phosphodiesterase.", "content": "The isolation of terminally cross-linked DNA and kinetics of venom phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370483"}
{"pmid": "4370485", "title": "The metabolism of 25-hydroxycholecalciferol by isolated renal tubules in vitro as studied by a new chromatographic technique.", "content": "The metabolism of 25-hydroxycholecalciferol by isolated renal tubules in vitro as studied by a new chromatographic technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370485"}
{"pmid": "4370477", "title": "The influence of the vegetative nerve system on the maximal conduction velocity in the atrioventricular bundle and in the cardiac ventricles measured by the differential quotient of QRS. Investigations in dogs.", "content": "The influence of the vegetative nerve system on the maximal conduction velocity in the atrioventricular bundle and in the cardiac ventricles measured by the differential quotient of QRS. Investigations in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370477"}
{"pmid": "4370486", "title": "The modulating effect of cholera enterotoxin on the immune response.", "content": "The modulating effect of cholera enterotoxin on the immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370486"}
{"pmid": "4370488", "title": "The phosphorylation and subsequent metabolism of 1-aminopropan-2-ol.", "content": "The phosphorylation and subsequent metabolism of 1-aminopropan-2-ol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370488"}
{"pmid": "4370489", "title": "The polyoma pseudovirion--its properties, production, and use in transferring DNA to mouse and human cells.", "content": "The polyoma pseudovirion--its properties, production, and use in transferring DNA to mouse and human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370489"}
{"pmid": "4370487", "title": "The nucleases from Acrocylindrium sp. IV. Purification and properties of exonuclease.", "content": "The nucleases from Acrocylindrium sp. IV. Purification and properties of exonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370487"}
{"pmid": "4370490", "title": "The polypeptide compositions of bovine cytochrome oxidase and its \"proteinase-treated\" derivative.", "content": "The polypeptide compositions of bovine cytochrome oxidase and its \"proteinase-treated\" derivative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370490"}
{"pmid": "4370491", "title": "The preparation of 1-deoxy-1-halogeno-D-fructoses.", "content": "The preparation of 1-deoxy-1-halogeno-D-fructoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370491"}
{"pmid": "4370492", "title": "The properties and origin of the proteins in the SV40 nucleoprotein complex.", "content": "The properties and origin of the proteins in the SV40 nucleoprotein complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370492"}
{"pmid": "4370493", "title": "The protective effects of nucleotides on the histamine hypersensitivity of Bordetella pertussis-treated mice.", "content": "The protective effects of nucleotides on the histamine hypersensitivity of Bordetella pertussis-treated mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370493"}
{"pmid": "4370494", "title": "The purification of glycerate kinase from Hyphomicrobium sp. and Pseudomonas AM1: product identification.", "content": "The purification of glycerate kinase from Hyphomicrobium sp. and Pseudomonas AM1: product identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370494"}
{"pmid": "4370495", "title": "The redox properties of the cytochromes of purified complex 3.", "content": "The redox properties of the cytochromes of purified complex 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370495"}
{"pmid": "4370496", "title": "The regulation of polyamine synthesis during the stringent control in Escherichia coli.", "content": "The regulation of polyamine synthesis during the stringent control in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370496"}
{"pmid": "4370497", "title": "The renin-angiotensin system and aldosterone secretion during sodium depletion in the rat.", "content": "The renin-angiotensin system and aldosterone secretion during sodium depletion in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370497"}
{"pmid": "4370499", "title": "The role of cyclic 3'5'-AMP and its derivatives in lipid and carbohydrate metabolism.", "content": "The role of cyclic 3'5'-AMP and its derivatives in lipid and carbohydrate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370499"}
{"pmid": "4370498", "title": "The role of calcium in insulin action. I. Purification and properties of enzymes regulating lipolysis in human adipose tissue: effects of cyclic-AMP and calcium ions.", "content": "The role of calcium in insulin action. I. Purification and properties of enzymes regulating lipolysis in human adipose tissue: effects of cyclic-AMP and calcium ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370498"}
{"pmid": "4370500", "title": "The role of the amino group in subunit association and receptor site interaction for ovine luteinizing hormone as studied by acylation.", "content": "The role of the amino group in subunit association and receptor site interaction for ovine luteinizing hormone as studied by acylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370500"}
{"pmid": "4370501", "title": "The role of the secretory immune system in protection against agents which infect the respiratory tract.", "content": "The role of the secretory immune system in protection against agents which infect the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370501"}
{"pmid": "4370503", "title": "The susceptibility of the fetus and child to chemical pollutants. Viral etiology of cancer: two hypotheses with relevance to chemical exposures.", "content": "The susceptibility of the fetus and child to chemical pollutants. Viral etiology of cancer: two hypotheses with relevance to chemical exposures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370503"}
{"pmid": "4370502", "title": "The state of water on hydrated collagen as studied by pulsed NMR.", "content": "The state of water on hydrated collagen as studied by pulsed NMR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370502"}
{"pmid": "4370504", "title": "The synthesis and biological activity of peptides corresponding to the first nineteen amino acids of adrenocorticotropin containing delta-aminovaleric and omega-aminocaprylic acids.", "content": "The synthesis and biological activity of peptides corresponding to the first nineteen amino acids of adrenocorticotropin containing delta-aminovaleric and omega-aminocaprylic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370504"}
{"pmid": "4370505", "title": "The synthesis of virus-specific polypeptides on polyribosomes isolated from the cells infected with encephalomyocarditis virus.", "content": "The synthesis of virus-specific polypeptides on polyribosomes isolated from the cells infected with encephalomyocarditis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370505"}
{"pmid": "4370506", "title": "The toxic optic neuropathies.", "content": "The toxic optic neuropathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370506"}
{"pmid": "4370507", "title": "The ultrastructure of erythropoiesis in two haemoglobinopathies.", "content": "The ultrastructure of erythropoiesis in two haemoglobinopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370507"}
{"pmid": "4370509", "title": "The use of lymphangiography in melanoma.", "content": "The use of lymphangiography in melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370509"}
{"pmid": "4370508", "title": "The use of conjugated oestrogen in oral contraception.", "content": "The use of conjugated oestrogen in oral contraception. To find a suitable contraceptive combination 11 dosage combinations of estrogen and megestrol acetate were studied clinically.  An additional combination for treatment of menopausal symptoms was used in 603 treatments, each with 21 pills.  A dose of 3.75 mg and even 4.0 mg of conjugated estrogen was not sufficient to inhibit ovulation.  Pregnancies occurred also when 21 daily doses of 3 mg conjugated estrogen were combined with 2 or 3 mg megestrol acetate daily.  Consequently, not even 3 mg megestrol acetate can be considered a sufficient dose to prevent the pentration of spermatozoa through the cervical mucus when used in combination with estrogens.  Clinically best results were obtained with following 2 combinations (2 and 7): conjugated estrogen 3.75 mg/day for 21 days + 5 mg megestrol acetate for the last 5 days and conjugated estrogen 4 mg/day for 21 days + 5 mg megestrol acetate for  the last 7 days.  The tolerance to conjugated estrogen was good in the whole series.  No embolism was observed, nor were any changes in the ASAT; GOT or ALAT; GPT values recorded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370508"}
{"pmid": "4370510", "title": "The value of resection in tumors involving the chest wall.", "content": "The value of resection in tumors involving the chest wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370510"}
{"pmid": "4370511", "title": "Theoretical analysis of the oxidation of amylose by periodate ion as an example of cooperative effects in polymer kinetics.", "content": "Theoretical analysis of the oxidation of amylose by periodate ion as an example of cooperative effects in polymer kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370511"}
{"pmid": "4370512", "title": "Threshold of the early components of the averaged electroencephalic response determined with tone pips and clicks during drug-induced sleep.", "content": "Threshold of the early components of the averaged electroencephalic response determined with tone pips and clicks during drug-induced sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370512"}
{"pmid": "4370513", "title": "Thyrotropin-induced aggregation-promoting factors of adult cultured thyroid cells.", "content": "Thyrotropin-induced aggregation-promoting factors of adult cultured thyroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370513"}
{"pmid": "4370514", "title": "Tissue cytochrome oxidase activity and copper, iron, and pantothenic acid nutrition in the growing rat.", "content": "Tissue cytochrome oxidase activity and copper, iron, and pantothenic acid nutrition in the growing rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370514"}
{"pmid": "4370515", "title": "Traffic of metabolites between blood and tissue.", "content": "Traffic of metabolites between blood and tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370515"}
{"pmid": "4370516", "title": "Transformation of hamster embryo and human embryo cells by temperature sensitive mutants of herpes simplex virus type 2.", "content": "Transformation of hamster embryo and human embryo cells by temperature sensitive mutants of herpes simplex virus type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370516"}
{"pmid": "4370517", "title": "Transformation-defective virus mutants in a class of morphologic revertants of sarcoma virus transformed nonproducer cells.", "content": "Transformation-defective virus mutants in a class of morphologic revertants of sarcoma virus transformed nonproducer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370517"}
{"pmid": "4370518", "title": "Transfusion-acquired cytomegalovirus infection in newborn infants.", "content": "Transfusion-acquired cytomegalovirus infection in newborn infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370518"}
{"pmid": "4370521", "title": "Transplantation of nervous system tumors in diffusion chambers.", "content": "Transplantation of nervous system tumors in diffusion chambers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370521"}
{"pmid": "4370520", "title": "Translation in vitro of total nuclear RNA from HeLa cell nuclei infected with adenovirus 2.", "content": "Translation in vitro of total nuclear RNA from HeLa cell nuclei infected with adenovirus 2. Total heterogeneous nuclear RNA from HeLa cells infected with adenovirus for 18-20 hr stimulates amino acid incorporation into protein in a cell-free system from Ehrlich ascites tumors. This stimulation of protein synthesis by the nuclear RNA requires intact nuclei. The role of nuclei in this system is unknown, but evidence is presented that the nuclei are involved in the conversion of high-molecular-weight RNA to low-molecular-weight species. Some of the newly synthesized polypeptides appear to resemble the virion polypeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370520"}
{"pmid": "4370523", "title": "Transport of ACTH across human placenta.", "content": "Transport of ACTH across human placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370523"}
{"pmid": "4370524", "title": "Traumatic induction of an intraoral reinfection with herpes simplex virus. Report of a case.", "content": "Traumatic induction of an intraoral reinfection with herpes simplex virus. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370524"}
{"pmid": "4370522", "title": "Transport of lipids in insects.", "content": "Transport of lipids in insects. Many insect species are almost completely dependent on lipids for their metabolic needs, although this is usually a function of developmental stage. The primary storage organ is the fat body, which can constitute 50% of the fresh weight of the insect and also acts as the major metabolic center (analogous to the vertebrate adipose tissue and liver). Bathing the fat body (and all other tissues and organs) is the hemolymph, the main functions of which are to transport nutrient substrates to utilization sites and to deliver metabolic wastes to the excretory system. Although neutral lipids are stored as triglycerides, in times of need they appear to be endergonically released into the hemolymph as diglycerides in the majority of insects thus far studied (particularly silkmoths and locusts). Indeed, diglycerides constitute the largest neutral lipid fraction in the hemolymph of silkmoths, locusts, cockroaches, bugs, etc. In the hemolymph the diglyceride is found as a constituent of specific lipoproteins, and one specific lipoprotein class (lipoprotein I; high density lipoprotein) appears to be necessary for the transport of diglyceride from the fat body cell into the hemolymph. This particular lipoprotein is also involved in the transport of cholesterol from the gut into the hemolymph. Thus, lipoprotein I appears to be the major neutral lipid and sterol transport agent in the insects studied and, in addition, plays a regulatory role in the release of both diglycerides and sterols. Hemolymph lipoprotein II (very high density lipoprotein) may be important in providing protein and lipid to the insect ovary during oogenesis. Ecdysone, the polyhydroxy steroidal insect molting hormone, is probably carried \"free\" in the hemolymph, although reports exist of specific hemolymph-binding proteins in some species. The other major insect growth hormone, juvenile hormone, is transported by hemolymph lipoproteins in silkmoths and locusts and by a lower molecular weight hemolymph protein in the tobacco hornworm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370522"}
{"pmid": "4370526", "title": "Trophoblastic disease diagnosis and management.", "content": "Trophoblastic disease diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370526"}
{"pmid": "4370525", "title": "Treatment of acute cholecystitis by routine urgent operation.", "content": "Treatment of acute cholecystitis by routine urgent operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370525"}
{"pmid": "4370527", "title": "Tumor viruses at Cold Spring Harbor.", "content": "Tumor viruses at Cold Spring Harbor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370527"}
{"pmid": "4370528", "title": "Turnover of phosphatidylglycerol in Streptococcus sanguis.", "content": "Turnover of phosphatidylglycerol in Streptococcus sanguis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370528"}
{"pmid": "4370529", "title": "Two cases of pseudo-gout.", "content": "Two cases of pseudo-gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370529"}
{"pmid": "4370530", "title": "Two forms of mouse interferon messenger RNA.", "content": "Two forms of mouse interferon messenger RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370530"}
{"pmid": "4370531", "title": "Two routes for synthesis of phosphoenolpyruvate from C4-dicarboxylic acids in Escherichia coli.", "content": "Two routes for synthesis of phosphoenolpyruvate from C4-dicarboxylic acids in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370531"}
{"pmid": "4370532", "title": "Ultrastructural changes in the smooth musculature of antrum and pylorus in presence of ulcus ventriculi.", "content": "Ultrastructural changes in the smooth musculature of antrum and pylorus in presence of ulcus ventriculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370532"}
{"pmid": "4370519", "title": "Transient effect of angiotensin II infusion into the lateral ventricle of the brain on the blood ADH level in dogs.", "content": "Transient effect of angiotensin II infusion into the lateral ventricle of the brain on the blood ADH level in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370519"}
{"pmid": "4370533", "title": "Ultrastructural evidence for leakage of lysosomal contents after phagocytosis of monosodium urate crystals. A mechanism of gouty inflammation.", "content": "Ultrastructural evidence for leakage of lysosomal contents after phagocytosis of monosodium urate crystals. A mechanism of gouty inflammation. To obtain direct evidence for the mechanism involved in gouty inflammation, human leukocytes were incubated with synthetic monosodium urate microcrystals. To trace the phago(lyso)somal contents, colloidal carbon, ferritin, Thorotrast(R) or horseradish peroxidase was added to the incubation medium, or acid phosphatase activity was localized cytochemically. The interaction was analyzed in time sequence by electron microscopy. By 5 minutes' incubation, urate crystals and tracers had appeared in the single membrane-bounded vacuoles of leukocytes. After 30 minutes' incubation, the vacuoles containing the urate crystals and the tracers were found in more than 50% of the leukocyte population. The phago(lyso)somal membrane was occasionally discontinuous, and the tracers were found in the free cytoplasm near the membrane opening as well. After 60 minutes' or more incubation, the phago(lyso)somal changes and the cytoplasmic localization of the tracers were common, and many cells showed signs of degeneration. Urate crystals mixed in cell debris were often found to be ingested by other leukocytes. These results have been interpreted as follows. Monosodium urate crystals are avidly phagocytized. The urate crystal-containing phagosomes eventually become phagolysosomes. The phagolysosomal membrane is damaged and the contents leak out into the cytoplasm. The leakage of the hydrolases initiates the host cell injury. The urate crystals released by cell disruption are again phagocytized by other cells and the series of events are repeated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370533"}
{"pmid": "4370534", "title": "Ultrastructural studies of early nidation in pregnancy and pseudopregnancy.", "content": "Ultrastructural studies of early nidation in pregnancy and pseudopregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370534"}
{"pmid": "4370535", "title": "Ultrastructure of the inclusion bodies and nuclear abnormalities in beta-thalassemic erythroblasts.", "content": "Ultrastructure of the inclusion bodies and nuclear abnormalities in beta-thalassemic erythroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370535"}
{"pmid": "4370536", "title": "Ultrastructure of tumors induced in mice by Moloney and Harvey strains of murine sarcoma virus.", "content": "Ultrastructure of tumors induced in mice by Moloney and Harvey strains of murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370536"}
{"pmid": "4370537", "title": "Unit responses in the hypothalamus.", "content": "Unit responses in the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370537"}
{"pmid": "4370538", "title": "Unstable hemoglobins and thalassemia: some properties of Hb Köln.", "content": "Unstable hemoglobins and thalassemia: some properties of Hb Köln.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370538"}
{"pmid": "4370540", "title": "Ureteral and vesical metastases in nephroblastoma.", "content": "Ureteral and vesical metastases in nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370540"}
{"pmid": "4370539", "title": "Uptake of 2-deoxyglucose by BALB-3T3 cells: changes after polyoma infection.", "content": "Uptake of 2-deoxyglucose by BALB-3T3 cells: changes after polyoma infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370539"}
{"pmid": "4370541", "title": "Use of stochastic signals in evaluation of the dynamic properties of a neuronal system.", "content": "Use of stochastic signals in evaluation of the dynamic properties of a neuronal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370541"}
{"pmid": "4370542", "title": "Use of unithiol for reducing radiation hazard of renal scintigraphy with chlormerodrin 203Hg. I. Estimation of the urinary excretion of 203Hg.", "content": "Use of unithiol for reducing radiation hazard of renal scintigraphy with chlormerodrin 203Hg. I. Estimation of the urinary excretion of 203Hg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370542"}
{"pmid": "4370543", "title": "Use of unithiol for reducing radiation hazard of renal scintigraphy with chlormerodrin 203Hg. II. Scintigraphic estimation.", "content": "Use of unithiol for reducing radiation hazard of renal scintigraphy with chlormerodrin 203Hg. II. Scintigraphic estimation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370543"}
{"pmid": "4370544", "title": "Value structure as a predictor of type of discharge among residential addicts.", "content": "Value structure as a predictor of type of discharge among residential addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370544"}
{"pmid": "4370545", "title": "Variable sensitivity of different hypertensives to constant infusion of angiotensin.", "content": "Variable sensitivity of different hypertensives to constant infusion of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370545"}
{"pmid": "4370546", "title": "Variables related to success in a medical rehabilitation setting.", "content": "Variables related to success in a medical rehabilitation setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370546"}
{"pmid": "4370548", "title": "Various aspects of alpha-thalassemia.", "content": "Various aspects of alpha-thalassemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370548"}
{"pmid": "4370547", "title": "Varicella dendritic keratitis.", "content": "Varicella dendritic keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370547"}
{"pmid": "4370549", "title": "Vastus lateralis cytochrome oxidase activity and its relationship to maximal oxygen consumption in man.", "content": "Vastus lateralis cytochrome oxidase activity and its relationship to maximal oxygen consumption in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370549"}
{"pmid": "4370550", "title": "Very early effects of aminonucleoside on some rat liver enzymes.", "content": "Very early effects of aminonucleoside on some rat liver enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370550"}
{"pmid": "4370551", "title": "Vesicular stomatitis virus envelope glycoprotein alterations induced by host cell transformation.", "content": "Vesicular stomatitis virus envelope glycoprotein alterations induced by host cell transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370551"}
{"pmid": "4370552", "title": "Virilization in pregnancy associated with polycystic ovary disease.", "content": "Virilization in pregnancy associated with polycystic ovary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370552"}
{"pmid": "4370553", "title": "Virogenic nontransformed cells isolated following infection of normal rat kidney cells with B77 strain Rous sarcoma virus.", "content": "Virogenic nontransformed cells isolated following infection of normal rat kidney cells with B77 strain Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370553"}
{"pmid": "4370554", "title": "Virus antibody in synovial fluid of rheumatoid and control patients.", "content": "Virus antibody in synovial fluid of rheumatoid and control patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370554"}
{"pmid": "4370556", "title": "Vitamin D physiology and its importance in dairy cattle: a review.", "content": "Vitamin D physiology and its importance in dairy cattle: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370556"}
{"pmid": "4370555", "title": "Visual loss: a rare complication following oil myelography. Case report and review of the literature.", "content": "Visual loss: a rare complication following oil myelography. Case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370555"}
{"pmid": "4370558", "title": "Waxes of the uropygial gland secretion of birds of the genus Parus.", "content": "Waxes of the uropygial gland secretion of birds of the genus Parus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370558"}
{"pmid": "4370557", "title": "Vitamin D: mode of action and biomedical applications.", "content": "Vitamin D: mode of action and biomedical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370557"}
{"pmid": "4370559", "title": "Workshop on possible pharmacologic mechanisms for enhancement of lung maturation.", "content": "Workshop on possible pharmacologic mechanisms for enhancement of lung maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370559"}
{"pmid": "4370561", "title": "14CO2 fixation and glycolate metabolism in the dark in isolated maize (Zea mays L.) bundle sheath strands.", "content": "14CO2 fixation and glycolate metabolism in the dark in isolated maize (Zea mays L.) bundle sheath strands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370561"}
{"pmid": "4370560", "title": "1Alpha-hydroxyvitamin D3. An analog of vitamin D which apparently acts by metabolism to 1alpha, 25-dihydroxyvitamin D3.", "content": "1Alpha-hydroxyvitamin D3. An analog of vitamin D which apparently acts by metabolism to 1alpha, 25-dihydroxyvitamin D3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370560"}
{"pmid": "4370562", "title": "3-Epi-20-hydroxyecdysone from meconium of the tobacco hornworm.", "content": "3-Epi-20-hydroxyecdysone from meconium of the tobacco hornworm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370562"}
{"pmid": "4370564", "title": "What do women want?", "content": "What do women want?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370564"}
{"pmid": "4370563", "title": "8-(6-Aminohexyl)-amino-adenine nucleotide derivatives for affinity chromatography.", "content": "8-(6-Aminohexyl)-amino-adenine nucleotide derivatives for affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370563"}
{"pmid": "4370567", "title": "Some applications of calorimetry in biochemistry and biology.", "content": "Some applications of calorimetry in biochemistry and biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370567"}
{"pmid": "4370569", "title": "U.S. childhood cancer deaths by cell type, 1960-68.", "content": "U.S. childhood cancer deaths by cell type, 1960-68.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370569"}
{"pmid": "4370570", "title": "What cyclic AMP is all about.", "content": "What cyclic AMP is all about.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370570"}
{"pmid": "4370571", "title": "High density lipoproteins in cholestasis.", "content": "High density lipoproteins in cholestasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370571"}
{"pmid": "4370575", "title": "Some diseases of zoo animals.", "content": "Some diseases of zoo animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370575"}
{"pmid": "4370578", "title": "Some hematologic and biochemical observations in the mongoose (Herpestes auropunctatus).", "content": "Some hematologic and biochemical observations in the mongoose (Herpestes auropunctatus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370578"}
{"pmid": "4370577", "title": "On a family with coexistence of phenotypes II and III hyperlipoproteinemia.", "content": "On a family with coexistence of phenotypes II and III hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370577"}
{"pmid": "4370580", "title": "Cell inoculum size and rate of subsequent exponential multiplication in human cell lines.", "content": "Cell inoculum size and rate of subsequent exponential multiplication in human cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370580"}
{"pmid": "4370587", "title": "Role of cyclic nucleotides in the nervous system.", "content": "Role of cyclic nucleotides in the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370587"}
{"pmid": "4370588", "title": "Role of cytochrome b5 in hydroxylation by a reconstituted cytochrome P-450-containing system.", "content": "Role of cytochrome b5 in hydroxylation by a reconstituted cytochrome P-450-containing system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370588"}
{"pmid": "4370589", "title": "Role of lipid in the formation and function of the respiratory system of Staphylococcus aureus.", "content": "Role of lipid in the formation and function of the respiratory system of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370589"}
{"pmid": "4370590", "title": "Loss of mitotic response of the thyroid gland to TSH in hypophysectomized rats and its partial restoration by anterior and posterior pituitary hormones.", "content": "Loss of mitotic response of the thyroid gland to TSH in hypophysectomized rats and its partial restoration by anterior and posterior pituitary hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370590"}
{"pmid": "4370592", "title": "Role of splenic arteriography in evaluation of malignant tumors in the body of the pancreas.", "content": "Role of splenic arteriography in evaluation of malignant tumors in the body of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370592"}
{"pmid": "4370593", "title": "Role of the amygdaloid complexes in the stress-induced release of ACTH in the rat.", "content": "Role of the amygdaloid complexes in the stress-induced release of ACTH in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370593"}
{"pmid": "4370591", "title": "Role of phospholipids in transport and enzymic reactions.", "content": "Role of phospholipids in transport and enzymic reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370591"}
{"pmid": "4370594", "title": "Role of 3-mercaptopyruvate sulfurtransferase in the formation of the iron-sulfur chromophore of adrenal ferredoxin.", "content": "Role of 3-mercaptopyruvate sulfurtransferase in the formation of the iron-sulfur chromophore of adrenal ferredoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370594"}
{"pmid": "4370597", "title": "Some properties of Ascaris suum allergen A.", "content": "Some properties of Ascaris suum allergen A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370597"}
{"pmid": "4370599", "title": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 48-1974.", "content": "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 48-1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370599"}
{"pmid": "4370600", "title": "Host responses to infectious bovine rhinotracheitis virus. III. Isolation and immunologic activities of bovine T lymphocytes.", "content": "Host responses to infectious bovine rhinotracheitis virus. III. Isolation and immunologic activities of bovine T lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370600"}
{"pmid": "4370602", "title": "Fine structure of the adrenal gland in the duck (Anas platyrhynchos).", "content": "Fine structure of the adrenal gland in the duck (Anas platyrhynchos).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370602"}
{"pmid": "4370608", "title": "Poly(riboadenylic acid) and adjacent nucleotides in Rous sarcoma virus RNA.", "content": "Poly(riboadenylic acid) and adjacent nucleotides in Rous sarcoma virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370608"}
{"pmid": "4370609", "title": "Host-cell reactivation in mammalian cells. IV. Cell culture conditions affecting virus survival.", "content": "Host-cell reactivation in mammalian cells. IV. Cell culture conditions affecting virus survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370609"}
{"pmid": "4370611", "title": "Cell-mediated immunity to varicella-zoster virus: in vitro lymphocyte responses.", "content": "Cell-mediated immunity to varicella-zoster virus: in vitro lymphocyte responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370611"}
{"pmid": "4370610", "title": "Drug-induced phospholipidosis.", "content": "Drug-induced phospholipidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370610"}
{"pmid": "4370612", "title": "Drug-receptor-related stereoselectivities in fat cells.", "content": "Drug-receptor-related stereoselectivities in fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370612"}
{"pmid": "4370614", "title": "Post-transfusion hepatitis in a London hospital: results of a two-year prospective study. A report to the M.R.C. Blood Transfusion Research Committee by the Medical Research Council Working Party on Post-Transfusion Hepatitis.", "content": "Post-transfusion hepatitis in a London hospital: results of a two-year prospective study. A report to the M.R.C. Blood Transfusion Research Committee by the Medical Research Council Working Party on Post-Transfusion Hepatitis. Seven hundred and sixty-eight patients were seen and tested at frequent intervals after transfusion of whole blood. Eight patients were judged to have developed icteric or anicteric post-transfusion viral hepatitis, an incidence of 1%. Five were icteric and four of these were hepatitis B antigen (HB Ag) positive; two of these four died. One of the fatal cases and one non-fatal HB Ag positive case had received HB Ag positive blood. Two other antigen-positive patients had received blood or plasma or both which had not been tested for antigen.Thirty-five patients showed conspicuous or sustained elevations of alanine transaminase without clinical features of hepatitis.Four were positive for HB Ag but had not received antigen positive blood.Two who had received antigen positive blood remained antigen negative, but one developed hepatitis B antibody (HB Ab).Two other patients were also transfused with plasma.Five had serological evidence of cytomegalovirus (CMV) infection accompanying the enzyme changes.One patient who had received HB Ag positive blood remained antigen-negative and showed no abnormalities.Five patients who became HB Ag positive, although they had been given antigen-negative blood, remained clinically and biochemically well.Cytomegalovirus primary infection or reactivation occurred in another 32 patients; five had isolated, transient enzyme rises, one other was associated with a drug-induced focal liver necrosis and 26 showed no enzyme changes. Epstein-Barr virus infections, one of which was associated with a transient upset of enzyme activity, were detected in five patients. There were no cases of post-perfusion syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370614"}
{"pmid": "4370615", "title": "Visna-maedi in sheep.", "content": "Visna-maedi in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370615"}
{"pmid": "4370616", "title": "Destabilization of membranes with chaotropic ions.", "content": "Destabilization of membranes with chaotropic ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370616"}
{"pmid": "4370618", "title": "Surface proteins of the erythrocyte membrane. Effect of aging.", "content": "Surface proteins of the erythrocyte membrane. Effect of aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370618"}
{"pmid": "4370619", "title": "Intracellular activity of medullary respiratory neurons.", "content": "Intracellular activity of medullary respiratory neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370619"}
{"pmid": "4370620", "title": "Extracellular toxins of Pseudomonas aeruginosa.", "content": "Extracellular toxins of Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370620"}
{"pmid": "4370621", "title": "Avenaciolide inhibition of anion transport in mitochondria.", "content": "Avenaciolide inhibition of anion transport in mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370621"}
{"pmid": "4370622", "title": "Intracisternal inclusions in nerve cells of cat ventromedial hypothalamic nucleus.", "content": "Intracisternal inclusions in nerve cells of cat ventromedial hypothalamic nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370622"}
{"pmid": "4370623", "title": "Characteristic ultrastructural changes in organs of newborn mice infected with EMC virus.", "content": "Characteristic ultrastructural changes in organs of newborn mice infected with EMC virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370623"}
{"pmid": "4370613", "title": "Dose-response analysis of angiotensin- and renin-induced drinking in the cat.", "content": "Dose-response analysis of angiotensin- and renin-induced drinking in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370613"}
{"pmid": "4370624", "title": "Characterization and comparison of rabbit blastokinin produced under various physiological and experimental conditions.", "content": "Characterization and comparison of rabbit blastokinin produced under various physiological and experimental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370624"}
{"pmid": "4370625", "title": "Characterization of the fraction obtained from the CNS of Jimpy mice by a procedure for myelin isolation.", "content": "Characterization of the fraction obtained from the CNS of Jimpy mice by a procedure for myelin isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370625"}
{"pmid": "4370626", "title": "Characterization of the insulin and somatomedin-C receptors in human placental cell membranes.", "content": "Characterization of the insulin and somatomedin-C receptors in human placental cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370626"}
{"pmid": "4370627", "title": "Characterization of Bacillus polymyxa amylase as an exo-acting(1 leads to 4)-alpha-D-glucan maltohydrolase.", "content": "Characterization of Bacillus polymyxa amylase as an exo-acting(1 leads to 4)-alpha-D-glucan maltohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370627"}
{"pmid": "4370628", "title": "Degradation of oil shale by sulfur-oxidizing bacteria.", "content": "Degradation of oil shale by sulfur-oxidizing bacteria. Approximately 40% of oil shale can be solubilized by the action of sulfur-oxidizing bacteria. Thiobacillus thiooxidans and Thiobacillus concretivorous are equally effective in solubilization. Continuous leaching experiments show that this process can be completed within 14 days. The growth of Thiobacillus and the production of acid were measured under several conditions. Almost all of the CaMg(CO(3))(2) was removed by this process, leaving a complex of silica and kerogen that could be burned as low-energy fuel. The silica-kerogen complex had not yet been biologically degraded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370628"}
{"pmid": "4370629", "title": "Circadian variation in human urinary cyclic AMP and the effect of different diets on this rhythm.", "content": "Circadian variation in human urinary cyclic AMP and the effect of different diets on this rhythm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370629"}
{"pmid": "4370630", "title": "Intradiaphragmatic cyst: a diagnostic challenge.", "content": "Intradiaphragmatic cyst: a diagnostic challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370630"}
{"pmid": "4370631", "title": "Estradiol receptor in the human fallopian tube.", "content": "Estradiol receptor in the human fallopian tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370631"}
{"pmid": "4370632", "title": "Estradiol receptors in the oviduct and uterus of the rabbit.", "content": "Estradiol receptors in the oviduct and uterus of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370632"}
{"pmid": "4370633", "title": "Leukaemogenic effect of repeated inoculations with small doses of Tennant virus in BALB-c mice.", "content": "Leukaemogenic effect of repeated inoculations with small doses of Tennant virus in BALB-c mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370633"}
{"pmid": "4370634", "title": "The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic agents, cyclic nucleotides and methyl xanthines.", "content": "The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic agents, cyclic nucleotides and methyl xanthines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370634"}
{"pmid": "4370636", "title": "Spinal pathways for cortical influences on lumbar motoneurons in rats.", "content": "Spinal pathways for cortical influences on lumbar motoneurons in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370636"}
{"pmid": "4370637", "title": "Spinal transmission of autonomic processes.", "content": "Spinal transmission of autonomic processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370637"}
{"pmid": "4370638", "title": "Isovaleric acid as a precursor of odd numbered iso fatty acids in Tetrahymena.", "content": "Isovaleric acid as a precursor of odd numbered iso fatty acids in Tetrahymena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370638"}
{"pmid": "4370639", "title": "Mammalian acyl carrier protein. Dissociation of the acyl carrier protein subunit from dog liver fatty acid synthetase complex.", "content": "Mammalian acyl carrier protein. Dissociation of the acyl carrier protein subunit from dog liver fatty acid synthetase complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370639"}
{"pmid": "4370641", "title": "A team approach to a disease survey on an aboriginal island (Orchid Island, Taiwan). V. Arboviral, rickettsial and brucella antibodies on Orchid Island.", "content": "A team approach to a disease survey on an aboriginal island (Orchid Island, Taiwan). V. Arboviral, rickettsial and brucella antibodies on Orchid Island.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370641"}
{"pmid": "4370643", "title": "Glutamate dehydrogenase activity related to histopathological grade of hepatocellular carcinoma in man.", "content": "Glutamate dehydrogenase activity related to histopathological grade of hepatocellular carcinoma in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370643"}
{"pmid": "4370644", "title": "Monoaminergic enzymes other than MAO.", "content": "Monoaminergic enzymes other than MAO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370644"}
{"pmid": "4370646", "title": "Neuraminidase treatment of adrenal cells increases their response to cholera enterotoxin.", "content": "Neuraminidase treatment of adrenal cells increases their response to cholera enterotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370646"}
{"pmid": "4370645", "title": "Monoamines and the regulation of vigilance and sleep.", "content": "Monoamines and the regulation of vigilance and sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370645"}
{"pmid": "4370647", "title": "Neuraminidase: its effect on synaptic transmission.", "content": "Neuraminidase: its effect on synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370647"}
{"pmid": "4370650", "title": "Manganese in photosynthetic oxygen evolution. I. Electron paramagnetic resonance study of the environment of manganese in Tris-washed chloroplasts.", "content": "Manganese in photosynthetic oxygen evolution. I. Electron paramagnetic resonance study of the environment of manganese in Tris-washed chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370650"}
{"pmid": "4370649", "title": "The anatomy and physiology of the oviduct.", "content": "The anatomy and physiology of the oviduct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370649"}
{"pmid": "4370651", "title": "Methanesulfonic acid derivative of p,p'-diaminodiphenylsulfone. II. Pharmacokinetics and availability of parental drug in rabbit.", "content": "Methanesulfonic acid derivative of p,p'-diaminodiphenylsulfone. II. Pharmacokinetics and availability of parental drug in rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370651"}
{"pmid": "4370652", "title": "Cholangiocarcinoma: a clinicopathologic study of five cases with ultrastructural observations.", "content": "Cholangiocarcinoma: a clinicopathologic study of five cases with ultrastructural observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370652"}
{"pmid": "4370653", "title": "Mechanically self-induced muzzle alopecia in mice.", "content": "Mechanically self-induced muzzle alopecia in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370653"}
{"pmid": "4370648", "title": "Intramitochondrial localization of arginase appearing in chicken liver upon starvation.", "content": "Intramitochondrial localization of arginase appearing in chicken liver upon starvation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370648"}
{"pmid": "4370654", "title": "Mechanism of stimulation of murine type-C RNA tumor virus production by glucocorticoids: post-transcriptional effects.", "content": "Mechanism of stimulation of murine type-C RNA tumor virus production by glucocorticoids: post-transcriptional effects. We have previously shown that dexamethasone stimulates production of type-C virus from seemingly normal murine fibroblasts (BALB/3T3) and from transformed (Kirsten sarcoma-leukemia virus) nonproducing cells (BALB/K3T3) induced by 5-iododeoxyuridine. In this report, we further examine the mechanism of this effect by using BALB/K3T3 cells. Several observations suggest that this effect is post-transcriptional. The optimal stimulation by dexamethasone is obtained when dexamethasone is given 24 to 48 h after 5-iododeoxyuridine induction. Although this effect is late, time course experiments suggest that dexamethasone does not act to promote release of preformed virions. The stimulation by dexamethasone is blocked when cells are treated with cordycepin (3'-deoxyadenosine) during the first 24 h of induction, but not when cordycepin is added later. Conversely, interferon, which inhibits virus production, interferes with dexamethasone when it is added late or after removal of the steroid. The results of molecular hybridization experiments show that there is no detectable increase in Kirsten sarcoma-leukemia virus-specific RNA in dexamethasone-treated cells (with or without 5-iododeoxyuridine). The results of the time course studies, and the cordycepin, interferon, and hybridization experiments, suggest that the effect of dexamethasone on type-C virus production in this system is post-transcriptional.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370654"}
{"pmid": "4370655", "title": "Mechanisms by which activated normal macrophages destroy syngeneic rat tumour cells in vitro. Cytokinetics, non-involvement of T lymphocytes, and effect of metabolic inhibitors.", "content": "Mechanisms by which activated normal macrophages destroy syngeneic rat tumour cells in vitro. Cytokinetics, non-involvement of T lymphocytes, and effect of metabolic inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370655"}
{"pmid": "4370657", "title": "Mechanisms of blood-vascular reactions of the primate lung to acute endotoxemia.", "content": "Mechanisms of blood-vascular reactions of the primate lung to acute endotoxemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370657"}
{"pmid": "4370658", "title": "Mechanisms of inflammation.", "content": "Mechanisms of inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370658"}
{"pmid": "4370656", "title": "Mechanisms for development of diabetic hypertriglyceridemia in streptozotocin-treated rats. Effect of diet and duration of insulin deficiency.", "content": "Mechanisms for development of diabetic hypertriglyceridemia in streptozotocin-treated rats. Effect of diet and duration of insulin deficiency. A combined ultrastructural and functional approach was employed to define the effects of duration of diabetes and of diet on various aspects of lipid metabolism in rats with severe streptozotocin (SZ)-induced insulin deficiency. Plasma triglyceride (TG) levels rose to a mean of 479 mg/100 ml 24 h after SZ administration in rats eating a fat-free, high carbohydrate diet as compared to a mean of 324 mg/100 ml in rats eating a high fat diet. These changes were associated with a commensurate increase in hepatocyte Golgi very low density lipoprotein (VLDL) content, but only a small increase in estimates of VLDL-TG secretion rate (post-Triton WR 1339 increment in plasma TG level). Although these findings are consistent with the thesis that VLDL-TG synthesis and secretion are increased 24 h after administration of SZ, it seemed unlikely that the observed increase in VLDL-TG secretion could entirely account for the severity of the hypertriglyceridemia. Thus, although lipoprotein removal rate was not measured directly, it was necessary to postulate that a defect in VLDL-TG removal was also present at this stage. Hypertriglyceridemia was still present 7 days later, only in this instance plasma TG levels were higher in rats eating the high fat diet (a mean of 589 mg/100 ml, as compared to 263 mg/100 ml). Rats with diabetes of 7-day duration had a 50% decrease in both TG entry rate and hepatocyte Golgi complex VLDL content, irrespective of diet. Thus, there was no evidence of increased VLDL-TG secretion in chronic insulin deficiency. In this instance, although not assessed directly, it was necessary to postulate that the hypertriglyceridemia in chronically insulin-deficient rats is due entirely to a defect in lipoprotein removal, involving both dietary and endogenous fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370656"}
{"pmid": "4370660", "title": "The antiviral activity of some related benzo(b)thiophene derivatives. I. Initial screening tests.", "content": "The antiviral activity of some related benzo(b)thiophene derivatives. I. Initial screening tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370660"}
{"pmid": "4370661", "title": "Ocular malformations in chick embryo resulting from diminished intraneural pressure.", "content": "Ocular malformations in chick embryo resulting from diminished intraneural pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370661"}
{"pmid": "4370662", "title": "Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes.", "content": "Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370662"}
{"pmid": "4370664", "title": "Comparative immunogenicity of irradiated, neuraminidase treated, and fused cells of a strain-restricted sarcoma.", "content": "Comparative immunogenicity of irradiated, neuraminidase treated, and fused cells of a strain-restricted sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370664"}
{"pmid": "4370663", "title": "Preparation of isolated fat cells and fat cell \"ghosts\"; methods for assaying adenylate cyclase activity and levels of cyclic AMP.", "content": "Preparation of isolated fat cells and fat cell \"ghosts\"; methods for assaying adenylate cyclase activity and levels of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370663"}
{"pmid": "4370666", "title": "Comparative studies of viral infections of the developing forebrain. II. Electron microscopic studies of rat virus and bluetongue vaccine virus infections.", "content": "Comparative studies of viral infections of the developing forebrain. II. Electron microscopic studies of rat virus and bluetongue vaccine virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370666"}
{"pmid": "4370665", "title": "Comparative studies of viral infections of the developing forebrain. I. Pathogenesis of rat virus and bluetongue vaccine virus infections in neonatal hamsters.", "content": "Comparative studies of viral infections of the developing forebrain. I. Pathogenesis of rat virus and bluetongue vaccine virus infections in neonatal hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370665"}
{"pmid": "4370668", "title": "Univariate and multivariate models for evaluating long-term changes in neurobiological development, maturity and aging.", "content": "Univariate and multivariate models for evaluating long-term changes in neurobiological development, maturity and aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370668"}
{"pmid": "4370667", "title": "Suprarenal cortical reserve capacity in Kwashiorkor.", "content": "Suprarenal cortical reserve capacity in Kwashiorkor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370667"}
{"pmid": "4370669", "title": "Comparison between effects of cyclic AMP, dibutyryl cyclic AMP and luteinizing hormone on ovarian glycolysis.", "content": "Comparison between effects of cyclic AMP, dibutyryl cyclic AMP and luteinizing hormone on ovarian glycolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370669"}
{"pmid": "4370670", "title": "Comparison of adenylate kinase from liver and muscle of normal mice and those with an hereditary muscular dystrophy.", "content": "Comparison of adenylate kinase from liver and muscle of normal mice and those with an hereditary muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370670"}
{"pmid": "4370671", "title": "Comparison of antigenicity of hepatoma cells, normal liver cells, foetal liver cells and chemically damaged liver cells in guinea-pigs immunized with hepatomata using the macrophage migration inhibition test.", "content": "Comparison of antigenicity of hepatoma cells, normal liver cells, foetal liver cells and chemically damaged liver cells in guinea-pigs immunized with hepatomata using the macrophage migration inhibition test. The macrophage migration inhibition test has been used to study the immune responses of guinea-pigs immunized with injections of whole cells of both an allogeneic and a syngeneic hepatoma grown as established cell lines in tissue culture.A clear dose-response relationship between tumour cell concentration and migration inhibition was seen in immunized animals and no significant migration inhibition was seen in control animals. There was no cross reaction between the two tumours used. There was no cross reaction between whole isolated normal liver cells and tumour cells, or between foetal liver cells and tumour cells. Whole isolated liver cells from carbon tetrachloride damaged livers caused some degree of migration inhibition in both normal and immunized guinea-pigs but, taking this into account, they did not appear to cross react with hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370671"}
{"pmid": "4370673", "title": "Urinary cyclic adenosine monophosphate excretion in diabetes insipidus of childhood. Effect of vasopressin and chlorpropamide.", "content": "Urinary cyclic adenosine monophosphate excretion in diabetes insipidus of childhood. Effect of vasopressin and chlorpropamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370673"}
{"pmid": "4370672", "title": "Comparison of the fractional post-coital test with the Sims-Huhner post-coital test.", "content": "Comparison of the fractional post-coital test with the Sims-Huhner post-coital test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370672"}
{"pmid": "4370674", "title": "Urinary excretion of adenosine 3' :5'-cyclic monophosphate in depressive illness.", "content": "Urinary excretion of adenosine 3' :5'-cyclic monophosphate in depressive illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370674"}
{"pmid": "4370675", "title": "Primary hyperparathyroidism. Preoperative evaluation and correlation with surgical findings.", "content": "Primary hyperparathyroidism. Preoperative evaluation and correlation with surgical findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370675"}
{"pmid": "4370676", "title": "Primary linitis plastica carcinoma of the colon.", "content": "Primary linitis plastica carcinoma of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370676"}
{"pmid": "4370677", "title": "Primary malignant hemangioendothelioma of the liver. Report of a successful case of resection and review of the Japanese literature.", "content": "Primary malignant hemangioendothelioma of the liver. Report of a successful case of resection and review of the Japanese literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370677"}
{"pmid": "4370678", "title": "Primary reninism, a surgically curable form of hypertension.", "content": "Primary reninism, a surgically curable form of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370678"}
{"pmid": "4370679", "title": "Primary sequence of U-1 nuclear ribonucleic acid of Novikoff hepatoma ascites cells.", "content": "Primary sequence of U-1 nuclear ribonucleic acid of Novikoff hepatoma ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370679"}
{"pmid": "4370680", "title": "Urinary steroid dynamics after a single dose of metyrapone.", "content": "Urinary steroid dynamics after a single dose of metyrapone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370680"}
{"pmid": "4370691", "title": "Ultrastructural effects of dietary galactoflavin on mouse hepatocytes.", "content": "Ultrastructural effects of dietary galactoflavin on mouse hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370691"}
{"pmid": "4370689", "title": "Ultrastructural and biochemical studies of the isolated fibrillar component of nucleoli from Novikoff hepatoma ascites cells.", "content": "Ultrastructural and biochemical studies of the isolated fibrillar component of nucleoli from Novikoff hepatoma ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370689"}
{"pmid": "4370690", "title": "Ultrastructural changes in the nervous system after chronic exposure to halothane.", "content": "Ultrastructural changes in the nervous system after chronic exposure to halothane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370690"}
{"pmid": "4370693", "title": "Ultrastructural features of papillomatosis and carcinoma of nipple ducts. The significance of myoepithelial cells and basal lamina in benign, \"questionable,\" and malignant lesions.", "content": "Ultrastructural features of papillomatosis and carcinoma of nipple ducts. The significance of myoepithelial cells and basal lamina in benign, \"questionable,\" and malignant lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370693"}
{"pmid": "4370694", "title": "Ultrastructural observation of possible nerve endings in rat sebaceous gland.", "content": "Ultrastructural observation of possible nerve endings in rat sebaceous gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370694"}
{"pmid": "4370695", "title": "Ultrastructural observations on the spinal cords of piglets affected with congenital tremor type AIV.", "content": "Ultrastructural observations on the spinal cords of piglets affected with congenital tremor type AIV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370695"}
{"pmid": "4370696", "title": "Ultrastructure and three-dimensional organization of synaptic glomeruli in rat somatosensory thalamus.", "content": "Ultrastructure and three-dimensional organization of synaptic glomeruli in rat somatosensory thalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370696"}
{"pmid": "4370698", "title": "Ultrastructure of Michaelis-Gutmann body. A study of a case of testicular malacoplakia.", "content": "Ultrastructure of Michaelis-Gutmann body. A study of a case of testicular malacoplakia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370698"}
{"pmid": "4370699", "title": "An easy radioimmunological microassay of renin activity, concentration and substrate in human and animal plasma and tissues based on angiotensin I trapping by antibody.", "content": "An easy radioimmunological microassay of renin activity, concentration and substrate in human and animal plasma and tissues based on angiotensin I trapping by antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370699"}
{"pmid": "4370692", "title": "Ultrastructural evolution of experimentally induced lipid inclusions in rat and mouse hepatocytes indicative for the recovery of livers from effects of benzidamine and triacetyloleandomycin.", "content": "Ultrastructural evolution of experimentally induced lipid inclusions in rat and mouse hepatocytes indicative for the recovery of livers from effects of benzidamine and triacetyloleandomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370692"}
{"pmid": "4370697", "title": "Ultrastructure of the lamina propria in the ovine seminiferous tubule. Development and some endocrine considerations.", "content": "Ultrastructure of the lamina propria in the ovine seminiferous tubule. Development and some endocrine considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370697"}
{"pmid": "4370701", "title": "Neonatal changes in the concentration of rat liver cyclic AMP and of serum glucose, free fatty acids, insulin, pancreatic, and total glucagon in man and in the rat.", "content": "Neonatal changes in the concentration of rat liver cyclic AMP and of serum glucose, free fatty acids, insulin, pancreatic, and total glucagon in man and in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370701"}
{"pmid": "4370702", "title": "Neonatal keratitis due to herpes virus hominis type i infection.", "content": "Neonatal keratitis due to herpes virus hominis type i infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370702"}
{"pmid": "4370703", "title": "Neonatal plasma lipids as measured in cord blood.", "content": "Neonatal plasma lipids as measured in cord blood. The status of cord blood screening of plasma lipids is reviewed, emphasizing the problems associated with the diagnosis of familial hyperlipoproteinemia (HLP), particularly type II (hyperbetalipoproteinemia), in the neonate. For 2937 neonates in this study the mean +/- standard deviation (SD) of plasma cholesterol was 70.3 +/- 16.9 mg/dl. The mean triglyceride level of 1805 neonates was 39.6 +/- 19.3 mg/dl. The mean level of beta-cholesterol in 240 neonates was 34.3 +/- 10.9 mg/dl and the correlation between total and beta-cholesterol was high (r=0.89). By convention, the upper limit of normal was defined as the mean + 2 SD, and these levels for total cholesterol, triglyceride and beta-cholesterol were 100, 80 and 55 mg/dl respectively. Only by careful follow-up of hyperlipidemic neonates can the incidence of HLP and the worth of early diagnosis be assessed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370703"}
{"pmid": "4370704", "title": "Repeated examinations, using the laparotomy sampling technique, of the gastro-intestinal microflora of baboons fed a natural or a synthetic diet.", "content": "Repeated examinations, using the laparotomy sampling technique, of the gastro-intestinal microflora of baboons fed a natural or a synthetic diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370704"}
{"pmid": "4370706", "title": "Isolation and characterization of two distinct types of HVJ (Sendai virus) spikes.", "content": "Isolation and characterization of two distinct types of HVJ (Sendai virus) spikes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370706"}
{"pmid": "4370705", "title": "Isolation and characterization of rifampin-resistant and streptolydigin-resistant mutants of Bacillus subtilis with altered sporulation properties.", "content": "Isolation and characterization of rifampin-resistant and streptolydigin-resistant mutants of Bacillus subtilis with altered sporulation properties. Mutants of Bacillus subtilis with altered deoxyribonucleic-dependent ribonucleic acid polymerase activity have been isolated and characterized. These mutants, selected as strains resistant to rifampin or streptolydigin, demonstrate drug-resistant in vitro ribonucleic acid synthesis. Sporeforming ability and support of phage infection are altered in many of the mutants. Mutations to rifampin and streptolydigin resistance have been located on the B. subtilis chromosome and ordered relative to the markers cysA14 and str.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370705"}
{"pmid": "4370707", "title": "Radiation effects on NAD-and DNA-metabolism in mouse spleen.", "content": "Radiation effects on NAD-and DNA-metabolism in mouse spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370707"}
{"pmid": "4370708", "title": "Isolation of hen's egg yolk very low density lipoproteins by DEAE-cellulose chromatography.", "content": "Isolation of hen's egg yolk very low density lipoproteins by DEAE-cellulose chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370708"}
{"pmid": "4370709", "title": "Isolation of kidney lysosomes.", "content": "Isolation of kidney lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370709"}
{"pmid": "4370710", "title": "Isolation of modified liver lysosomes.", "content": "Isolation of modified liver lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370710"}
{"pmid": "4370711", "title": "Isolation of myelin from nerve tissue.", "content": "Isolation of myelin from nerve tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370711"}
{"pmid": "4370712", "title": "Isolation of nuclei from liver and other tissues.", "content": "Isolation of nuclei from liver and other tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370712"}
{"pmid": "4370713", "title": "Isolation of plasma membranes from rat and mouse livers and hepatomas.", "content": "Isolation of plasma membranes from rat and mouse livers and hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370713"}
{"pmid": "4370714", "title": "Isolation of rat liver plasma membrane fragments in isotonic sucrose.", "content": "Isolation of rat liver plasma membrane fragments in isotonic sucrose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370714"}
{"pmid": "4370715", "title": "Variation of serotype in strains of Bordetella pertussis.", "content": "Variation of serotype in strains of Bordetella pertussis. The four main serotypes of Bordetella pertussis (1, 2, 3; 1, 2; 1, 3; 1) undergo spontaneous variation involving loss or gain of antigen 2 or antigen 3. By serial subculture from single colonies on charcoal-blood-agar medium, we have detected loss-mutations from type 1, 2, 3 to 1, 2 or 1, 3, and from type 1, 2 to type 1. Likewise we have found gain-mutations from type 1 to 1, 2 or 1, 3, and from 1, 2 to 1, 2, 3.These mutations apparently occur with a high frequency in some strains. Other strains have a lower mutation-rate and are more stable antigenically. We have not detected, by this method, either gain- or loss-mutations from the type 1, 3 strains that we have tested.These findings offer an explanation for the changes in serotype that occur during the course of a pertussis infection in the child and in the marmoset. They also constitute a warning on the possible antigenic instability of laboratory strains, especially relevant in the production, absorption and testing of diagnostic antisera and in the preparation of pertussis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370715"}
{"pmid": "4370716", "title": "Isolation of ACTH-induced protein from adrenal perfusate.", "content": "Isolation of ACTH-induced protein from adrenal perfusate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370716"}
{"pmid": "4370718", "title": "Radiation therapy in bronchiolar-alveolar cell carcinoma: a case report.", "content": "Radiation therapy in bronchiolar-alveolar cell carcinoma: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370718"}
{"pmid": "4370717", "title": "Formation of 5'-nucleotides of 6-methylmercaptopurine ribonucleoside in human tissues in vitro.", "content": "Formation of 5'-nucleotides of 6-methylmercaptopurine ribonucleoside in human tissues in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370717"}
{"pmid": "4370720", "title": "Isolation, identification, and characterization of six bovine picornavirus isolates.", "content": "Isolation, identification, and characterization of six bovine picornavirus isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370720"}
{"pmid": "4370721", "title": "Variations of cytotoxic antibodies to cells with herpes simplex virus antigens in women with progressing or regressing cancerous lesions of the cervix.", "content": "Variations of cytotoxic antibodies to cells with herpes simplex virus antigens in women with progressing or regressing cancerous lesions of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370721"}
{"pmid": "4370722", "title": "Chelator-sensitive in chloroplast electron transport.", "content": "Chelator-sensitive in chloroplast electron transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370722"}
{"pmid": "4370723", "title": "The background to Arthur Harden's discovery of cozymase.", "content": "The background to Arthur Harden's discovery of cozymase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370723"}
{"pmid": "4370726", "title": "Solubilization of membrane-associated tumour-specific antigens by beta-glucosidase.", "content": "Solubilization of membrane-associated tumour-specific antigens by beta-glucosidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370726"}
{"pmid": "4370727", "title": "Antibiotic susceptibility testing of Pseudomonas aeruginosa: selection of a control strain and criteria for magnesium and calcium content in media.", "content": "Antibiotic susceptibility testing of Pseudomonas aeruginosa: selection of a control strain and criteria for magnesium and calcium content in media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370727"}
{"pmid": "4370728", "title": "Inhibition of cytochrome c oxidase by hydrophobic metal chelators.", "content": "Inhibition of cytochrome c oxidase by hydrophobic metal chelators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370728"}
{"pmid": "4370729", "title": "Inhibition of growth of gonadal dependent structures by arginine vasotocin and purified bovine pineal fractions in immature mice and hamsters.", "content": "Inhibition of growth of gonadal dependent structures by arginine vasotocin and purified bovine pineal fractions in immature mice and hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370729"}
{"pmid": "4370730", "title": "Inhibition of Flac transfer by the fin+ I-like plasmid R62.", "content": "Inhibition of Flac transfer by the fin+ I-like plasmid R62. Flac mutants have been isolated in Escherichia coli K-12 which carry dominant mutations resulting in insensitivity to transfer inhibition by the Fin(+) I-like plasmid R62. These mutants were still sensitive to transfer inhibition by the fin(+) F-like plasmid R100 and, conversely, FlactraO(-) and traP(-) mutants, which are insensitive to R100 inhibition, were still sensitive to R62. The sites of action of the two inhibition systems are therefore different. Furthermore, inhibition by R62, unlike R100, did not require an F-specified product. Like R100, R62 prevented transfer, pilus formation, and surface exclusion and, therefore, probably inhibits expression of the transfer operon traA through traI. However, R62 was different from R100 in inhibiting transfer of J-independent mutants, indicating that its effect on the transfer operon is probably direct rather than via traJ. This is consistent with the different sites of action of the two inhibition systems. None of the Flac mutants overproduced pili in the absence of R62, although one mutant differing from those described above showed increased levels of transfer and surface exclusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370730"}
{"pmid": "4370725", "title": "Amoebic liver abscess--a clinical study.", "content": "Amoebic liver abscess--a clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370725"}
{"pmid": "4370733", "title": "Antibodies to herpes-simplex virus in the cerebrospinal fluid of patients with herpetic encephalitis.", "content": "Antibodies to herpes-simplex virus in the cerebrospinal fluid of patients with herpetic encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370733"}
{"pmid": "4370734", "title": "Antibodies to Epstein-Barr virus and some other herpesviruses in patients with sarcoidosis, pulmonary tuberculosis and erythema nodosum.", "content": "Antibodies to Epstein-Barr virus and some other herpesviruses in patients with sarcoidosis, pulmonary tuberculosis and erythema nodosum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370734"}
{"pmid": "4370736", "title": "Metabolic effects of cortisol and corticotrophins in the Australian brush-tailed opossum, Trichosurus vulpecula (Kerr).", "content": "Metabolic effects of cortisol and corticotrophins in the Australian brush-tailed opossum, Trichosurus vulpecula (Kerr).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370736"}
{"pmid": "4370737", "title": "Metabolic regulation by multifunctional glucose-6-phosphatase.", "content": "Metabolic regulation by multifunctional glucose-6-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370737"}
{"pmid": "4370735", "title": "Metabolic adaptation of spiny mice (Acomys cahirinus) transferred from the desert to laboratory diets.", "content": "Metabolic adaptation of spiny mice (Acomys cahirinus) transferred from the desert to laboratory diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370735"}
{"pmid": "4370738", "title": "Metabolic studies on 125I-labeled baby hamster kidney cell plasma membranes.", "content": "Metabolic studies on 125I-labeled baby hamster kidney cell plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370738"}
{"pmid": "4370739", "title": "Metabolism of iodinated very low density lipoprotein in the rat. Autoradiographic localization in the liver.", "content": "Metabolism of iodinated very low density lipoprotein in the rat. Autoradiographic localization in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370739"}
{"pmid": "4370740", "title": "Metabolism of plasma triglycerides in endogenous hypertriglyceridemia.", "content": "Metabolism of plasma triglycerides in endogenous hypertriglyceridemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370740"}
{"pmid": "4370741", "title": "Foodborne disease surveillance: Washington State.", "content": "Foodborne disease surveillance: Washington State.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370741"}
{"pmid": "4370742", "title": "The bovine respiratory disease complex.", "content": "The bovine respiratory disease complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370742"}
{"pmid": "4370743", "title": "A rubredoxin-like mononuclear FeS4 derivative of adrenal iron-sulfur protein (adrenodoxin).", "content": "A rubredoxin-like mononuclear FeS4 derivative of adrenal iron-sulfur protein (adrenodoxin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370743"}
{"pmid": "4370744", "title": "Cerebrocerebellar communication systems.", "content": "Cerebrocerebellar communication systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370744"}
{"pmid": "4370745", "title": "L-Ribulokinase from an initiator constitutive mutant.", "content": "L-Ribulokinase from an initiator constitutive mutant. The N-terminal sequence of l-ribulokinase (EC 2.7.1.16) isolated from an initiator constitutive (araI(-)) mutant is identical to wild-type kinase, indicating that the I(c) mutation probably lies outside of kinase structural gene araB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370745"}
{"pmid": "4370746", "title": "99mTc pyrophosphate for diagnostic bone imaging.", "content": "99mTc pyrophosphate for diagnostic bone imaging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370746"}
{"pmid": "4370747", "title": "Radical treatment of recurrent cytosarcoma phylloides.", "content": "Radical treatment of recurrent cytosarcoma phylloides. Malignant cystosarcoma phylloides is a rare breast cancer which frequently recurs locally before metastasizing. Local recurrence of cystosarcoma phylloides is unlike adenocarcinoma of the breast since it does not necessarily indicate systemic metastases; and, therefore, aggressive surgery can cure a number of patients with locally recurrent tumor. The present report is an extreme example of a patient with locally recurrent malignant cystosarcoma phylloides, and it illustrates the value of radical surgery in controlling this disease which had previously recurred 21 times. Fifteen months following sternal resection, the patient enjoys her longest tumor-free interval in 16 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370747"}
{"pmid": "4370750", "title": "A receptor mediating sexual differentiation?", "content": "A receptor mediating sexual differentiation?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370750"}
{"pmid": "4370752", "title": "Bronchial carcinoma. A retrospective analysis of 2200 patients.", "content": "Bronchial carcinoma. A retrospective analysis of 2200 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370752"}
{"pmid": "4370756", "title": "Capacitation in vitro of rabbit spermatozoa with cyclic adenosine monophosphate and human follicular fluid.", "content": "Capacitation in vitro of rabbit spermatozoa with cyclic adenosine monophosphate and human follicular fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370756"}
{"pmid": "4370755", "title": "Principles of treatment of different types of parotid tumors.", "content": "Principles of treatment of different types of parotid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370755"}
{"pmid": "4370757", "title": "The clinical effects of CI 744 in chinchillas, Chinchilla villidera (Laniger).", "content": "The clinical effects of CI 744 in chinchillas, Chinchilla villidera (Laniger).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370757"}
{"pmid": "4370759", "title": "The coordination of sterically hindered bases to metalloporphyrins.", "content": "The coordination of sterically hindered bases to metalloporphyrins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370759"}
{"pmid": "4370748", "title": "Two cases of chemodectoma of the carotid body.", "content": "Two cases of chemodectoma of the carotid body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370748"}
{"pmid": "4370760", "title": "Endocrine evaluation and indications for surgery of functional pituitary adenomas.", "content": "Endocrine evaluation and indications for surgery of functional pituitary adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370760"}
{"pmid": "4370753", "title": "Cytochrome oxidase activity in isolated giant cell of the reticular formation from the rat brain stem following carbon monoxide intoxication (Cartesian micro-diver technique).", "content": "Cytochrome oxidase activity in isolated giant cell of the reticular formation from the rat brain stem following carbon monoxide intoxication (Cartesian micro-diver technique).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370753"}
{"pmid": "4370761", "title": "Direct binding of corticosterone and estradiol to rat liver nuclear non-histone proteins.", "content": "Direct binding of corticosterone and estradiol to rat liver nuclear non-histone proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370761"}
{"pmid": "4370758", "title": "The control of aldosterone secretion in nephrectomized man.", "content": "The control of aldosterone secretion in nephrectomized man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370758"}
{"pmid": "4370763", "title": "Effect of aging, organ allografting, and surgical stress on rat thymus histidine decarboxylase activity.", "content": "Effect of aging, organ allografting, and surgical stress on rat thymus histidine decarboxylase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370763"}
{"pmid": "4370764", "title": "Effect of beta-propiolactone inactivation of polyoma virus on viral functions.", "content": "Effect of beta-propiolactone inactivation of polyoma virus on viral functions. Polyoma virus was inactivated by treatment with beta-propiolactone. T-antigen production, polyoma-RNA synthesis, induction of host DNA synthesis (measured by incorporation of labeled thymidine into the cell culture), and in vitro transforming ability were inactivated to a similar degree by various beta-propiolactone concentrations (0.25% beta-propiolactone reduced these functions approximately 96%), whereas plaque-forming ability and the ability of the virus to replicate its DNA and to synthesize capsid antigen were inactivated by a given concentration of beta-propiolactone to a much greater degree (0.25% beta-propiolactone led to a reduction of plaque-forming ability of over 8 logs). The significance of these data and their relationship to previously published experiments are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370764"}
{"pmid": "4370762", "title": "Direct determination of molar ratios of various chemical constituents in endotoxic glycolipids in silicic acid scrapings from thin-layer chromatographic plates.", "content": "Direct determination of molar ratios of various chemical constituents in endotoxic glycolipids in silicic acid scrapings from thin-layer chromatographic plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370762"}
{"pmid": "4370767", "title": "Effect of different solid metals and metallic pairs on human sperm motility.", "content": "Effect of different solid metals and metallic pairs on human sperm motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370767"}
{"pmid": "4370765", "title": "Effect of calcium ions on steroid-binding spectra and pregnenolone formation in rat-adrenal mitochondria.", "content": "Effect of calcium ions on steroid-binding spectra and pregnenolone formation in rat-adrenal mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370765"}
{"pmid": "4370766", "title": "Effect of cysteine on the survival of mice with transplanted malignant thymoma.", "content": "Effect of cysteine on the survival of mice with transplanted malignant thymoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370766"}
{"pmid": "4370768", "title": "Effect of glucose on the fruiting body formation and adenosine 3',5'-cyclic monophosphate levels in Coprinus macrorhizus.", "content": "Effect of glucose on the fruiting body formation and adenosine 3',5'-cyclic monophosphate levels in Coprinus macrorhizus. The formation of fruiting bodies in the monokaryotic fis(c) strain and a dikaryon of Coprinus macrorhizus was inhibited by growth in high-glucose media. In high-glucose media the characteristic burst of adenosine 3',5'-cyclic monophosphate (cAMP) accumulation during fruiting-body formation was absent. Enzymatic activity assays revealed that mycelia grown in high-glucose media contained relatively lower amounts of adenylate cyclase and cAMP-phosphodiesterase than mycelia grown in low-glucose media. The synthesis of inducible d-serine deaminase and tryptophanase was repressed in high-glucose media. A mutant (gluR) in which the glucose repression of fruiting-body formation is affected was isolated by selection in high-glucose media. The mutation caused the cAMP levels to be no longer affected by glucose and affected ability to synthesize the inducible d-serine deaminase and tryptophanase. The gluR mutant was partially dominant in dikaryons. It is suggested that cAMP may play important roles in inducing fruiting bodies and in controlling inducible enzyme synthesis in C. macrorhizus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370768"}
{"pmid": "4370769", "title": "Effect of inflammation upon human gingival oxidative metabolism.", "content": "Effect of inflammation upon human gingival oxidative metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370769"}
{"pmid": "4370771", "title": "Effect of intraventricular norepinephrine on neuron activity in the medial forebrain bundle during self-stimulation behavior.", "content": "Effect of intraventricular norepinephrine on neuron activity in the medial forebrain bundle during self-stimulation behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370771"}
{"pmid": "4370770", "title": "Effect of inhibitors of proteolytic enzymes on the growth of normal and polyoma transformed BHK cells.", "content": "Effect of inhibitors of proteolytic enzymes on the growth of normal and polyoma transformed BHK cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370770"}
{"pmid": "4370772", "title": "Effect of manganese extraction on oxygen generation and EPR signal II in spinach chloroplasts.", "content": "Effect of manganese extraction on oxygen generation and EPR signal II in spinach chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370772"}
{"pmid": "4370774", "title": "Effect of peritubular infusion of angiotensin II on rat proximal nephron function.", "content": "Effect of peritubular infusion of angiotensin II on rat proximal nephron function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370774"}
{"pmid": "4370773", "title": "Effect of pentobarbital and sodium hydroxybutyrate on central mechanisms regulating vascular tone.", "content": "Effect of pentobarbital and sodium hydroxybutyrate on central mechanisms regulating vascular tone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370773"}
{"pmid": "4370775", "title": "Effect of pharmacological agents on human keratinocyte mitosis in vitro. I. Inhibition by adenine nucleotides.", "content": "Effect of pharmacological agents on human keratinocyte mitosis in vitro. I. Inhibition by adenine nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370775"}
{"pmid": "4370776", "title": "Effect of polyinosinic-polycytidylic acid in dogs experimentally infected with infectious canine hepatitis virus.", "content": "Effect of polyinosinic-polycytidylic acid in dogs experimentally infected with infectious canine hepatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370776"}
{"pmid": "4370777", "title": "Effect of pregnancy on cytoplasmic and mitochondrial enzymes in human and animal myometrium.", "content": "Effect of pregnancy on cytoplasmic and mitochondrial enzymes in human and animal myometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370777"}
{"pmid": "4370778", "title": "Effect of secretagogues on membrane parameters of adenohypophysial cells.", "content": "Effect of secretagogues on membrane parameters of adenohypophysial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370778"}
{"pmid": "4370779", "title": "Effect of sleep-wake cycle reversal on luteinizing hormone secretory pattern in puberty.", "content": "Effect of sleep-wake cycle reversal on luteinizing hormone secretory pattern in puberty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370779"}
{"pmid": "4370780", "title": "Effect of tumor-promoting phorbol esters on the normal and the isoproterenol-elevated level of adenosine 3',5'-cyclic monophosphate in mouse epidermis in vivo.", "content": "Effect of tumor-promoting phorbol esters on the normal and the isoproterenol-elevated level of adenosine 3',5'-cyclic monophosphate in mouse epidermis in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370780"}
{"pmid": "4370782", "title": "Effect of xanthothricin on the respiratory chain.", "content": "Effect of xanthothricin on the respiratory chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370782"}
{"pmid": "4370783", "title": "Effect of zinc deficiency from day 18 of gestation and-or during lactation on the development of some rat brain enzymes.", "content": "Effect of zinc deficiency from day 18 of gestation and-or during lactation on the development of some rat brain enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370783"}
{"pmid": "4370784", "title": "Effect of TSH on iodine metabolism and intermediary metabolism in tissue from patients with Graves' disease.", "content": "Effect of TSH on iodine metabolism and intermediary metabolism in tissue from patients with Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370784"}
{"pmid": "4370785", "title": "Effect of 1,3-butanediol on hepatic fatty acid synthesis and metabolite levels in the rat.", "content": "Effect of 1,3-butanediol on hepatic fatty acid synthesis and metabolite levels in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370785"}
{"pmid": "4370786", "title": "Effect of 2-nitrosonaphthalene on bacteria and bacteriophage.", "content": "Effect of 2-nitrosonaphthalene on bacteria and bacteriophage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370786"}
{"pmid": "4370781", "title": "Effect of various dietary fats on the size and distribution of lymph fat particles in rat.", "content": "Effect of various dietary fats on the size and distribution of lymph fat particles in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370781"}
{"pmid": "4370787", "title": "Selected recent vistas in bone pathology.", "content": "Selected recent vistas in bone pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370787"}
{"pmid": "4370788", "title": "Induction of aspermatogenesis in guinea pig through immunization with lactate dehydrogenase-x isozyme.", "content": "Induction of aspermatogenesis in guinea pig through immunization with lactate dehydrogenase-x isozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370788"}
{"pmid": "4370790", "title": "Detection of sequence heterology by use of the N. Crassa nucleases.", "content": "Detection of sequence heterology by use of the N. Crassa nucleases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370790"}
{"pmid": "4370789", "title": "Detection of neoplastic lesions with radiogallium(67Ga citrate). Clinical-statistical report on 125 cases.", "content": "Detection of neoplastic lesions with radiogallium(67Ga citrate). Clinical-statistical report on 125 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370789"}
{"pmid": "4370791", "title": "Induction of the postsynaptic membrane.", "content": "Induction of the postsynaptic membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370791"}
{"pmid": "4370792", "title": "Detection of trophoblast specific antigen in normal and neoplastic trophoblast.", "content": "Detection of trophoblast specific antigen in normal and neoplastic trophoblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370792"}
{"pmid": "4370793", "title": "Infections of swine with pseudorabies virus and enteroviruses: laboratory confirmation, clinical and epizootiologic features.", "content": "Infections of swine with pseudorabies virus and enteroviruses: laboratory confirmation, clinical and epizootiologic features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370793"}
{"pmid": "4370794", "title": "Defective immune responses and malignancy.", "content": "Defective immune responses and malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370794"}
{"pmid": "4370796", "title": "Selective radioprotection in extracellular space.", "content": "Selective radioprotection in extracellular space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370796"}
{"pmid": "4370795", "title": "Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia.", "content": "Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia. An assay has been developed for specific measurement of two different lipase activities in postheparin plasma. Lipoprotein lipase, derived from extrahepatic sources, is measured as protamine-inactivated lipase activity; hepatic lipase activity is protamine-resistant under the conditions of this assay. In 100 normal subjects, both enzyme activities were noted to be related to age and sex. Protamine-resistant lipase, which comprised 46-95% of the total activity, was highest in men over 18. Protamine-inactivated lipase activity was greatest in younger males and was age-correlated in women, doubling between the second and sixth decades. In 12 patients with hyperchylomicronemia, including five previously shown to have familial type I hyperlipoproteinemia, protamine-inactivated lipase activity was markedly reduced, whereas protamine-resistant lipase was below normal in only 1. The results were not due to lack of plasma activator, presence of plasma inhibitor, or diet, and the deficiency was not overcome by increasing the provoking dose of heparin from 10 U to 75 U/kg. Mean values for both lipase activities were not reduced in 32 other patients with hyperchylomicronemia, nine with \"floating beta\" lipoproteins (type III hyperlipoproteinemia), and 23 with hyperprebetalipoproteinemia (type IV). Mean protamine-resistant lipase activity was below normal in a group of four women with hypothyroidism, in whom protamine-inactivated lipase was not reduced. Both of the lipase activities were capable of hydrolyzing lipid in very low-density lipoproteins, but the relative rate of hydrolysis of chylomicrons by protamine-resistant lipase was markedly limited. These results indicate the importance of distinguishing between lipases of hepatic and extra-hepatic origin in the measurement of postheparin lipolytic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370795"}
{"pmid": "4370797", "title": "Defective simian virus 40 genomes: isolation and growth of individual clones.", "content": "Defective simian virus 40 genomes: isolation and growth of individual clones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370797"}
{"pmid": "4370801", "title": "Effects of alpha- and beta-receptor blocking agents on catecholamine and 5-hydroxytryptamine induced peroxidase and amylase secretion from guinea pig submandibular gland.", "content": "Effects of alpha- and beta-receptor blocking agents on catecholamine and 5-hydroxytryptamine induced peroxidase and amylase secretion from guinea pig submandibular gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370801"}
{"pmid": "4370802", "title": "Effects of buffers and pH on in vitro binding of 67Ga by L1210 leukemic cells.", "content": "Effects of buffers and pH on in vitro binding of 67Ga by L1210 leukemic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370802"}
{"pmid": "4370803", "title": "Effects of clofibrate on mitochondrial function.", "content": "Effects of clofibrate on mitochondrial function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370803"}
{"pmid": "4370804", "title": "Effects of cyclic neucleotide monophosphates (cAMP, cGMP, cIMP, dibutyryl-cAMP) on transtubular net fluxes in rat kidneys.", "content": "Effects of cyclic neucleotide monophosphates (cAMP, cGMP, cIMP, dibutyryl-cAMP) on transtubular net fluxes in rat kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370804"}
{"pmid": "4370805", "title": "Effects of dose on the induction of  dominant-lethal mutations and heritable translocations with ethyl methanesulfonate in male mice.", "content": "Effects of dose on the induction of  dominant-lethal mutations and heritable translocations with ethyl methanesulfonate in male mice. Genetic damage by ethyl methanesulfonate (EMS) in male mice was measured at doses ranging from 50 to 300 mg/kg with dominant-lethal mutations and reciprocal translocations as endpoints. No appreciable increase in dominant-lethal mutations was detected following a dose of 100 mg/kg. Dominant lethals induced by EMS were convincingly detected only after a dose of 150 mg/kg, but in the translocation experiment an increase in the genetic effect was detectable at the 50 mg/kg dose. It is likely that dominant lethals had also been induced at the 50 and 100 mg/kg doses, but were not detected due to the relative insensitivity of the dominant..lethal procedure. Thus, for detection of low levels of EMS-induced chromosome breakage, translocations are a much more reliable endpoint than are dominant-lethal mutations. A procedure for large-scale screening of induced translocations is described.-The dominant-lethal dose-response curve, plotted on the basis of living embryos as a percentage of the control value, is clearly not linear as it is markedly concave downward. Similarly, the translocation dose-response curve showed a more rapid increase in the number of translocations with dose than would be expected on the basis of dose-square kinetics. It is clear for both of these endpoints that the effectiveness of EMS in inducing chromosome breakage is proportionately much lower at low doses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370805"}
{"pmid": "4370806", "title": "Effects of dose on the induction of dominant-lethal mutations with triethylenemelamine in male mice.", "content": "Effects of dose on the induction of dominant-lethal mutations with triethylenemelamine in male mice. Dose effects of triethylenemelamine (TEM) in the induction of dominant-lethal mutations were studied at the early spermatozoon, midspermatid and spermatocyte stages. The pattern of effects on spermatocytes, unlike midspermatids and early spermatozoa, indicated possible cytotoxic damage, so for the determination of TEM dose-response curves in the induction of genetic damage only the data for midspermatids and early spermatozoa were used. The TEM dose-effect curves for those two stages differ markedly from ethyl methanesulfonate (EMS) dose-effect curves. Beginning with the lowest doses at which significant effects are observed, there is a considerably more rapid increase in dominant-lethal effects with dose of EMS than TEM. Another marked difference between the two compounds is in the ratio of the genetically effective dose (as measured by dominant-lethal mutations) to the lethal dose. The ratio is 1:100 for TEM and only 1:3.5 for EMS; thus, TEM is mutagenic far below its toxic level. Obviously, these results have important implications not only for our understanding of the nature of chemical induction and recovery of chromosomal aberrations but also for the practical problems of evaluating the mutagenic effects of chemicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370806"}
{"pmid": "4370807", "title": "Effects of gonadotrophins, dibutyryl cyclic AMP and prostaglandin E2 on amino acid transport and glycolysis in isolated rat corpora lutea.", "content": "Effects of gonadotrophins, dibutyryl cyclic AMP and prostaglandin E2 on amino acid transport and glycolysis in isolated rat corpora lutea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370807"}
{"pmid": "4370808", "title": "Effects of intraventricular infusions of ACTH1-24 and ACTH4-10 on LH release, ovulation and behavior in the rabbit.", "content": "Effects of intraventricular infusions of ACTH1-24 and ACTH4-10 on LH release, ovulation and behavior in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370808"}
{"pmid": "4370809", "title": "Effects of papaverine derivatives on cyclic 3',5'-AMP phosphodiesterase and relaxation of rabbit ileum.", "content": "Effects of papaverine derivatives on cyclic 3',5'-AMP phosphodiesterase and relaxation of rabbit ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370809"}
{"pmid": "4370811", "title": "Effects of pH and enzyme inhibitors on apparent generation of angiotensin I in human plasma.", "content": "Effects of pH and enzyme inhibitors on apparent generation of angiotensin I in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370811"}
{"pmid": "4370810", "title": "Effects of progesterone and four synthetic progestagens on sodium balance and the renin-aldosterone system in man.", "content": "Effects of progesterone and four synthetic progestagens on sodium balance and the renin-aldosterone system in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370810"}
{"pmid": "4370812", "title": "Effects of sympathetic stimulation on facial muscle contractions.", "content": "Effects of sympathetic stimulation on facial muscle contractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370812"}
{"pmid": "4370813", "title": "Effects of tiletamine on spinal cord synaptic transmission.", "content": "Effects of tiletamine on spinal cord synaptic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370813"}
{"pmid": "4370816", "title": "Effects on tumor growth in vivo by manipulation of the tumor immune response.", "content": "Effects on tumor growth in vivo by manipulation of the tumor immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370816"}
{"pmid": "4370814", "title": "Defects of two temperature-sensitive lysyl-transfer ribonucleic acid synthetase mutants of Bacillus subtilis.", "content": "Defects of two temperature-sensitive lysyl-transfer ribonucleic acid synthetase mutants of Bacillus subtilis. Two temperature-sensitive mutants (lysS1 and lysS2) of the lysyl-transfer ribonucleic acid synthetase (l-lysine:tRNA ligase [adenosine 5'-monophosphate], EC 6.1.1.6) of Bacillus subtilis have been isolated. Although protein synthesis is inhibited in both mutants at the restrictive temperature (42 to 45 C), the mutants remain viable in a minimal medium. In comparison with the wild-type lysyl-tRNA synthetase, the l-lysine-dependent exchange of [(32)P]pyrophosphate with adenosine 5'-triphosphate (ATP) for both mutant enzymes is decreased. The lysS1 enzyme is completely defective in the ATP-dependent attachment of l-lysine to tRNA, whereas the lysS2 enzyme has 3- to 10-fold reduced levels of this activity. Temperature-resistant transformants have wild-type enzyme levels, whereas partial revertants to temperature resistance have varied levels of enzyme activity. The attachment and exchange activities of the lysS2 enzyme are more heat labile in vitro than the wild-type enzyme, as is the attachment activity of a partial revertant of the lysS1 mutant. The lysS1 and the lysS2 lysyl-tRNA synthetases have higher apparent K(m) values for lysine and ATP, in both the activation and the attachment reactions. The lysS2 enzyme has a V(max) for tRNA(lys) one-third that of the wild-type enzyme. Molecular weights of approximately 150,000 for the wild-type and lysS2 enzymes and approximately 76,000 for the lysS1 enzyme were estimated from sedimentation positions in sucrose density gradients assayed by the ATP-pyrophosphate exchange activity. We propose that the two mutations (lysS1 and lysS2) directly affect the sites for exchange activity, but indirectly alter attachment activity as a consequence of defective subunit association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370814"}
{"pmid": "4370815", "title": "Effects of DMSO on vacuole formation, contractile vacuole function, and nuclear division in Tetrahymena pyriformis GL.", "content": "Effects of DMSO on vacuole formation, contractile vacuole function, and nuclear division in Tetrahymena pyriformis GL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370815"}
{"pmid": "4370818", "title": "Structural studies of avian myeloblastosis virus: absence of leukemogenic activity of the core component.", "content": "Structural studies of avian myeloblastosis virus: absence of leukemogenic activity of the core component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370818"}
{"pmid": "4370817", "title": "Structural and functional heterogeneity of the murine cytomegalovirus genome.", "content": "Structural and functional heterogeneity of the murine cytomegalovirus genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370817"}
{"pmid": "4370819", "title": "Structure of polysaccharides from the Polyporus tumulosus cell wall.", "content": "Structure of polysaccharides from the Polyporus tumulosus cell wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370819"}
{"pmid": "4370820", "title": "Molecular and clinical pharmacology of psoriasis.", "content": "Molecular and clinical pharmacology of psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370820"}
{"pmid": "4370821", "title": "Molecular and crystal structure of deoxyguanosine 5'-phosphate.", "content": "Molecular and crystal structure of deoxyguanosine 5'-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370821"}
{"pmid": "4370822", "title": "Mixed mesodermal tumors of the corpus uteri.", "content": "Mixed mesodermal tumors of the corpus uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370822"}
{"pmid": "4370824", "title": "Mixed substrate experiments with human brain monoamine oxidase.", "content": "Mixed substrate experiments with human brain monoamine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370824"}
{"pmid": "4370825", "title": "Lipid transport and the availability of insulin.", "content": "Lipid transport and the availability of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370825"}
{"pmid": "4370826", "title": "Rapid typing of herpes simplex virus strains using the indirect immunoperoxidase method.", "content": "Rapid typing of herpes simplex virus strains using the indirect immunoperoxidase method. The indirect immunoperoxidase technique with type-specific antisera was compared to kinetic neutralization for the typing of herpes simplex virus strains. There was complete agreement between the results obtained by kinetic neutralization and indirect immunoperoxidase. The indirect immunoperoxidase assay was far simpler to perform and interpret than the kinetic neutralization tests, and it offered a rapid means for the routine antigenic typing of herpes simplex isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370826"}
{"pmid": "4370828", "title": "Tinidazole in symptomatic intestinal amoebiasis.", "content": "Tinidazole in symptomatic intestinal amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370828"}
{"pmid": "4370830", "title": "Accidental infection of laboratory-reared Macaca mulatta with Trypanosoma cruzi.", "content": "Accidental infection of laboratory-reared Macaca mulatta with Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370830"}
{"pmid": "4370831", "title": "Ribodeoxyviruses and cancer.", "content": "Ribodeoxyviruses and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370831"}
{"pmid": "4370823", "title": "Mixed mesodermal tumour of the ovary.", "content": "Mixed mesodermal tumour of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370823"}
{"pmid": "4370832", "title": "The dependence of evoked transmitter release on external calcium ions at very low mean quantal contents.", "content": "The dependence of evoked transmitter release on external calcium ions at very low mean quantal contents. 1. The mean quantal content of the frog end-plate potential was examined under conditions that reduced evoked transmitter release to very low values.2. When the calcium concentration of the Ringer is reduced below 10(-4)M a deviation occurs from the fourth power dependence of the mean quantal content (m) on the calcium concentration such that more quanta are released than is expected from the behaviour of m at higher calcium concentrations.3. At 10(-5)M this extra quantal release is more than two orders of magnitude greater than that predicted by the fourth power relationship.4. The calcium dependence of very low values of m was studied in low calcium Ringer in which the calcium was buffered by either citrate or EDTA. It was found that in the fourth power dependence of m on the external calcium concentration changes rather suddenly to an approximately linear dependence.5. The inclusion of small concentrations of cobalt in the Ringer was found to reduce m to very low values even in the presence of millimolar concentrations of calcium.6. The fourth power dependence of m on the external calcium concentration at high values of m was unaffected by the presence of cobalt. At low quantal contents the transition to a linear dependence on external calcium was again seen, but was shifted to calcium concentrations that did not require buffering.7. The fourth power to linear transition is discussed in terms of its relevance to the relationship between m and the m.e.p.p. frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370832"}
{"pmid": "4370833", "title": "Age-dependent changes in the regulation of glycerolphosphate dehydrogenase in the rat brain and in a glial cell line.", "content": "Age-dependent changes in the regulation of glycerolphosphate dehydrogenase in the rat brain and in a glial cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370833"}
{"pmid": "4370835", "title": "The detection of chemical mutagens using the L5178y-Asn-murine leukemia in vitro and in  a host-mediated assay.", "content": "The detection of chemical mutagens using the L5178y-Asn-murine leukemia in vitro and in  a host-mediated assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370835"}
{"pmid": "4370834", "title": "Acrodermatitis enteropathica. A clinical and biochemical survey.", "content": "Acrodermatitis enteropathica. A clinical and biochemical survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370834"}
{"pmid": "4370836", "title": "The determination of 2'-O-methylnucleosides in RNA.", "content": "The determination of 2'-O-methylnucleosides in RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370836"}
{"pmid": "4370837", "title": "Triadic synaptic arrangements and their possible significance in the lateral geniculate nucleus of the monkey.", "content": "Triadic synaptic arrangements and their possible significance in the lateral geniculate nucleus of the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370837"}
{"pmid": "4370840", "title": "Sex differences in the elongation of the cranial base during pubescence.", "content": "Sex differences in the elongation of the cranial base during pubescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370840"}
{"pmid": "4370841", "title": "The differential diagnosis of neonatal hepatitis and biliary atresia.", "content": "The differential diagnosis of neonatal hepatitis and biliary atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370841"}
{"pmid": "4370842", "title": "A modification in the response of human astrocytes to visna virus.", "content": "A modification in the response of human astrocytes to visna virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370842"}
{"pmid": "4370844", "title": "Two distinct types of secretory granules in an islet cell carcinoma associated with the Zollinger-Ellison syndrome.", "content": "Two distinct types of secretory granules in an islet cell carcinoma associated with the Zollinger-Ellison syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370844"}
{"pmid": "4370843", "title": "Two distinct toxic proteins in Corynebacterium ulcerans.", "content": "Two distinct toxic proteins in Corynebacterium ulcerans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370843"}
{"pmid": "4370845", "title": "Pseudohomozygous type II hyperlipoproteinemia.", "content": "Pseudohomozygous type II hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370845"}
{"pmid": "4370846", "title": "Pseudomonas aeruginosa endocarditis in drug addicts.", "content": "Pseudomonas aeruginosa endocarditis in drug addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370846"}
{"pmid": "4370850", "title": "Three cases of hepatoma.", "content": "Three cases of hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370850"}
{"pmid": "4370852", "title": "Acute effects of alpha-methyldopa on mean blood pressure and plasma renin activity.", "content": "Acute effects of alpha-methyldopa on mean blood pressure and plasma renin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370852"}
{"pmid": "4370851", "title": "Three comparative techniques on tubo-plasty.", "content": "Three comparative techniques on tubo-plasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370851"}
{"pmid": "4370854", "title": "Trace elements in the human fallopian tube epithelium. Copper, zinc, manganese and potassium in the menstrual cycle.", "content": "Trace elements in the human fallopian tube epithelium. Copper, zinc, manganese and potassium in the menstrual cycle. A study was undertaken to determine the amounts of certain trace elements in the normal endosalpinx and their possible variation in the normal menstrual cycle.  Atomic absorption spectrophotometry was used to estimate the levels of copper, zinc, manganese, and potassium in 23 oviduct specimens which were divided into 4 groups according to the phase of the cycle: 1) early proliferative (EP), Cycle  Days 6-10; 2) late proliferative (LP), Cycle Days 11-14; 3) early secretory (ESY, Cycle Days 16-22; and 4) late secretory (LS), Cycle Days 23-28.  A biopsy was taken from the mucosa of the intramural part, isthmus, and ampulla in each tube.  Findings indicated no differences in copper, manganese, and potassium concentrations among the different parts of the tube in each phase of the cycle.  The zinc concentration was lower (p less than .05) in the ampulla (36.9 mcg/gm dry weight) than in the isthmus (57.4) and intramural part (69) in EP, but not in the other 3 phases.  In the 4 phases of the menstrual cycle there was no significant difference between the levels of zinc and manganese, whereas the potassium concentration was highest in ES (p less than .05) and the copper concentration was highest in LS (p  less than .05).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370854"}
{"pmid": "4370855", "title": "House fly and Drosophila cell cultures as hosts for human enteroviruses.", "content": "House fly and Drosophila cell cultures as hosts for human enteroviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370855"}
{"pmid": "4370849", "title": "Hemodynamic effects of acute and prolonged beta-adrenergic blockade in essential hypertension.", "content": "Hemodynamic effects of acute and prolonged beta-adrenergic blockade in essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370849"}
{"pmid": "4370857", "title": "Acute leukemia-associated antigens.", "content": "Acute leukemia-associated antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370857"}
{"pmid": "4370866", "title": "Increased activity of a factor (\"transferangiotensin\") favoring the binding of angiotensin II to arterial wall in hypertension.", "content": "Increased activity of a factor (\"transferangiotensin\") favoring the binding of angiotensin II to arterial wall in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370866"}
{"pmid": "4370865", "title": "Force-feeding effects on growth, carcass and blood composition in the young chick.", "content": "Force-feeding effects on growth, carcass and blood composition in the young chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370865"}
{"pmid": "4370867", "title": "Decreased response of plasma renin activity to orthostasis in diabetic patients with orthostatic hypotension.", "content": "Decreased response of plasma renin activity to orthostasis in diabetic patients with orthostatic hypotension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370867"}
{"pmid": "4370868", "title": "Increased transcapillary escape rate of albumin, IgG, and IgM during angiotensin-II-induced hypertension in man.", "content": "Increased transcapillary escape rate of albumin, IgG, and IgM during angiotensin-II-induced hypertension in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370868"}
{"pmid": "4370877", "title": "Connection between the structural organization of the aortic baroreceptor zone and characteristics of the baroreceptors.", "content": "Connection between the structural organization of the aortic baroreceptor zone and characteristics of the baroreceptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370877"}
{"pmid": "4370880", "title": "Soiled disposable diapers: a potential source of viruses.", "content": "Soiled disposable diapers: a potential source of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370880"}
{"pmid": "4370882", "title": "Proceedings: A role for noradrenaline and cyclic AMP in prostaglandin E1 Fever.", "content": "Proceedings: A role for noradrenaline and cyclic AMP in prostaglandin E1 Fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370882"}
{"pmid": "4370883", "title": "Proceedings: Assay of steroid hormone receptor in cancers, methodology and perspectives.", "content": "Proceedings: Assay of steroid hormone receptor in cancers, methodology and perspectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370883"}
{"pmid": "4370884", "title": "Proceedings: Clinical value of predictive tests for advanced breast cancer.", "content": "Proceedings: Clinical value of predictive tests for advanced breast cancer. With different endocrine measures remissions may be brought about in 30% of cases of advanced breast cancer.  Remissions seen after ablative procedures are best.  However, average survival of the 70% of nonresponders is short, especially if the therapy is adrenalectomy.  Several techniques to predict response have been investigated.  There is correlation between uptake of tritiated estradiol by the tumor tissue in vitro and the response to endocrinetherapy, but this test is not for routine use.  Correlation between the presence of receptors in breast cancer tissue and a favorable response to adrenalectomy or other endocrine treatments has been demonstrated.  As a first treatment nafoxidine can produce remissions but it prevents effectiveness of a second therapy with estrogens.  A successful first therapy with estrogens may be followed by a second remission with nafoxidine.  In 3 patients estrogen receptors have been negative in new biopsy material after hormone treatment although negative results had been reported in previous tests.  In these cases subjective remissions had been obtained with estrogens or androgens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370884"}
{"pmid": "4370885", "title": "Proceedings: Correlation of serum levels of hepatoma D23 antigen, antibody and immune complexes with growth of transplanted tumours.", "content": "Proceedings: Correlation of serum levels of hepatoma D23 antigen, antibody and immune complexes with growth of transplanted tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370885"}
{"pmid": "4370886", "title": "Proceedings: Effect of alpha-bungarotoxin and dendroaspis neurotoxins on acetylcholine responses of snail neurones.", "content": "Proceedings: Effect of alpha-bungarotoxin and dendroaspis neurotoxins on acetylcholine responses of snail neurones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370886"}
{"pmid": "4370887", "title": "Proceedings: Effects of angiotensin on fluid transport by rat jejunum in vivo.", "content": "Proceedings: Effects of angiotensin on fluid transport by rat jejunum in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370887"}
{"pmid": "4370888", "title": "Proceedings: Further evidence that secretin stimulates pancreatic secretion through adenosine 3,'5'-monophosphate (cyclic AMP).", "content": "Proceedings: Further evidence that secretin stimulates pancreatic secretion through adenosine 3,'5'-monophosphate (cyclic AMP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370888"}
{"pmid": "4370889", "title": "Proceedings: Oestrogen and androgen receptors in human breast cancer.", "content": "Proceedings: Oestrogen and androgen receptors in human breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370889"}
{"pmid": "4370890", "title": "Proceedings: Oestrogen receptors in human breast cancer.", "content": "Proceedings: Oestrogen receptors in human breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370890"}
{"pmid": "4370891", "title": "Proceedings: Pathways for bulk outflow of aqueous humour and cerebrospinal fluid.", "content": "Proceedings: Pathways for bulk outflow of aqueous humour and cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370891"}
{"pmid": "4370892", "title": "Proceedings: Plasma cyclic AMP response to glucagon in thyroid disease.", "content": "Proceedings: Plasma cyclic AMP response to glucagon in thyroid disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370892"}
{"pmid": "4370894", "title": "Proceedings: Radioimmunoassay of HCG, alpha and beta subunits in cancer.", "content": "Proceedings: Radioimmunoassay of HCG, alpha and beta subunits in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370894"}
{"pmid": "4370893", "title": "Proceedings: Possible role of mitochondria in transmitter release.", "content": "Proceedings: Possible role of mitochondria in transmitter release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370893"}
{"pmid": "4370895", "title": "Proceedings: The use of tissue culture in the screening of hormone sensitivity of endometrial carcinoma.", "content": "Proceedings: The use of tissue culture in the screening of hormone sensitivity of endometrial carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370895"}
{"pmid": "4370896", "title": "The effect of acetyl-coenzyme A on phosphate-activated glutaminase from pig kidney and brain.", "content": "The effect of acetyl-coenzyme A on phosphate-activated glutaminase from pig kidney and brain. Phosphate-activated glutaminase (EC 3.5.1.2; l-glutamine amidohydrolase) purified from pig kidney and brain is activated by CoA and short-chain acyl-CoA derivatives. Acetyl-CoA is the most powerful activator (K(A) about 0.2mm). Acetyl-CoA is maximally effective in the absence of other activating anions such as phosphate and citrate, and at low glutamine concentrations. The negative co-operative substrate activation observed at pH7 becomes more pronounced in the presence of acetyl-CoA. Similarly to phosphate, acetyl-CoA produces at high protein concentrations a different type of activation, which is time-dependent, depends on protein concentration and is accompanied by an increase in the sedimentation coefficient. Acetyl-CoA, phosphate and citrate appear to have binding sites in common. No significant difference was observed between kidney and brain phosphate-activated glutaminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370896"}
{"pmid": "4370897", "title": "The effect of antiestrogens on the nuclear binding of the estrogen receptor.", "content": "The effect of antiestrogens on the nuclear binding of the estrogen receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370897"}
{"pmid": "4370898", "title": "The effect of repeated vaccination in an enzootic foot-and-mouth disease area on the incidence of virus carrier cattle.", "content": "The effect of repeated vaccination in an enzootic foot-and-mouth disease area on the incidence of virus carrier cattle. A comparison was made of the incidence of foot-and-mouth disease virus ;carrier' cattle in an unvaccinated enzootic area and an area where routine 6-monthly vaccination with an inactivated vaccine had been carried out for 3-4 years. The incidence of carriers in the vaccinated area was 0.49% as compared to 3.34% in the non-vaccinated area. The results indicate that, provided the immune status of the vaccinated herd is maintained at a level sufficient to prevent outbreaks of clinical disease and the re-introduction of virus is prevented through livestock movement controls, it should be possible to eradicate the disease from an enzootic area through vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370898"}
{"pmid": "4370899", "title": "The effect of sulfhydryl inhibitors on substrate oxidation and proline transport with membrane preparations from Mycobacterium phlei.", "content": "The effect of sulfhydryl inhibitors on substrate oxidation and proline transport with membrane preparations from Mycobacterium phlei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370899"}
{"pmid": "4370900", "title": "The effect of the hypocholesterolemic drug clofibrate on liver mitochondrial biogenesis. A role for neutral mitochondrial proteases.", "content": "The effect of the hypocholesterolemic drug clofibrate on liver mitochondrial biogenesis. A role for neutral mitochondrial proteases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370900"}
{"pmid": "4370901", "title": "The effect of 3',5'-adenosine monophosphate on granulocyte adhesion.", "content": "The effect of 3',5'-adenosine monophosphate on granulocyte adhesion. Human granulocyte adhesion to glass capillary tubes was tested in the presence of agents that increase intracellular levels of cyclic 3',5'-adenosine monophosphate (cAMP). Adhesion was significantly reduced by 10(-3)-10(-4) M dibutyryl cAMP, 10(-4)-10(-6) M prostaglandin E(1) (PGE(1)), 10(-4)-10(-6) M histamine, or 10(-3) M theophylline. Adhesion was not suppressed by 10(-4) M theophylline unless it was combined with PGE(1) or histamine. Eosinophil and basophil adhesion was especially sensitive to suppression by the above agents. These findings suggest that intracellular cAMP may play a role in regulation of adhesiveness of human basophils, eosinophils, and neutrophils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370901"}
{"pmid": "4370902", "title": "The effects of a chronic limitation of sleep length.", "content": "The effects of a chronic limitation of sleep length.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370902"}
{"pmid": "4370903", "title": "The effects of prolonged physiologic estradiol therapy on the maturation of hypogonadal teen-agers.", "content": "The effects of prolonged physiologic estradiol therapy on the maturation of hypogonadal teen-agers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370903"}
{"pmid": "4370904", "title": "Biodegradative L-threonine deaminase of Salmonella typhimurium.", "content": "Biodegradative L-threonine deaminase of Salmonella typhimurium. The threonine deaminase formed under anaerobic conditions by Salmonella typhimurium is induced by l-serine and l-threonine, is catabolite repressible, requires cyclic adenosine 3',5'-monophosphate for its synthesis and adenylic acid for optimal activity, and is immunologically different from biosynthetic threonine deaminase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370904"}
{"pmid": "4370905", "title": "Protein kinase activity of bovine thyroid microsomes.", "content": "Protein kinase activity of bovine thyroid microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370905"}
{"pmid": "4370906", "title": "Protein kinase and cyclic 3',5'-AMP: significance of binding and activation constants.", "content": "Protein kinase and cyclic 3',5'-AMP: significance of binding and activation constants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370906"}
{"pmid": "4370907", "title": "Protein kinase in the sea urchin egg cortices. Its purification and characterization and some properties of an endogenous protein kinase in the cortices.", "content": "Protein kinase in the sea urchin egg cortices. Its purification and characterization and some properties of an endogenous protein kinase in the cortices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370907"}
{"pmid": "4370908", "title": "Protein model refinement based on x-ray data.", "content": "Protein model refinement based on x-ray data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370908"}
{"pmid": "4370909", "title": "Protein secretion in the rat ventral prostate and the relation of golgi vesicles, cisternae and vacuoles, as studied by electron microscope radioautography.", "content": "Protein secretion in the rat ventral prostate and the relation of golgi vesicles, cisternae and vacuoles, as studied by electron microscope radioautography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370909"}
{"pmid": "4370910", "title": "Epstein-Barr virus and human malignancies.", "content": "Epstein-Barr virus and human malignancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370910"}
{"pmid": "4370911", "title": "Epstein-Barr virus from P3HR-1 cells grown in chemically defined medium.", "content": "Epstein-Barr virus from P3HR-1 cells grown in chemically defined medium. A chemically defined medium, designated FCRC-1, supports the growth of P3HR-1 cells and concomitant replication of infectious Epstein-Barr virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370911"}
{"pmid": "4370913", "title": "One-electron reactions in biochemical systems as studied by pulse radiolysis. VI. Stages in the reduction of ferricytochrome c.", "content": "One-electron reactions in biochemical systems as studied by pulse radiolysis. VI. Stages in the reduction of ferricytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370913"}
{"pmid": "4370912", "title": "Caffeine inhibition of dark-repair: lack of reversal by adenosine-(3'5')-monophosphate.", "content": "Caffeine inhibition of dark-repair: lack of reversal by adenosine-(3'5')-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370912"}
{"pmid": "4370914", "title": "The electron transport system in the cochlear hair cell: the ultrastructural cytochemistry of respiratory enzymes in hair cell mitochondria of the guinea pig.", "content": "The electron transport system in the cochlear hair cell: the ultrastructural cytochemistry of respiratory enzymes in hair cell mitochondria of the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370914"}
{"pmid": "4370916", "title": "Subcellular distribution of transmitter-related enzyme activities in discrete areas of the rat dentate gyrus.", "content": "Subcellular distribution of transmitter-related enzyme activities in discrete areas of the rat dentate gyrus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370916"}
{"pmid": "4370915", "title": "The electrophoretic properties of some human blood cells. Effect of pH, ionic strength and antilymphocyte globulin.", "content": "The electrophoretic properties of some human blood cells. Effect of pH, ionic strength and antilymphocyte globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370915"}
{"pmid": "4370917", "title": "Subcellular fractionation of adipocytes.", "content": "Subcellular fractionation of adipocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370917"}
{"pmid": "4370921", "title": "Evidence for the existence of a fully reduced state of molybdoferredoxin during the functioning of nitrogenase, and the order of electron transfer from reduced ferredoxin.", "content": "Evidence for the existence of a fully reduced state of molybdoferredoxin during the functioning of nitrogenase, and the order of electron transfer from reduced ferredoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370921"}
{"pmid": "4370920", "title": "Evidence against the presence of cyclic AMP and related enzymes in selected strains of Bacteroides fragilis.", "content": "Evidence against the presence of cyclic AMP and related enzymes in selected strains of Bacteroides fragilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370920"}
{"pmid": "4370922", "title": "Evidence for the formation of a gamma-phosphorylated glutamyl residue in the Escherichia coli acetate kinase reaction.", "content": "Evidence for the formation of a gamma-phosphorylated glutamyl residue in the Escherichia coli acetate kinase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370922"}
{"pmid": "4370923", "title": "Evidence for the modification of fructose 1,6-bisphosphatase by two distinct lysosomal proteases.", "content": "Evidence for the modification of fructose 1,6-bisphosphatase by two distinct lysosomal proteases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370923"}
{"pmid": "4370918", "title": "Epidemiology of malignant neoplasms in children and juveniles in Warsaw Province between 1966-1970.", "content": "Epidemiology of malignant neoplasms in children and juveniles in Warsaw Province between 1966-1970.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370918"}
{"pmid": "4370924", "title": "Biogenic amines in cultured neuroblastoma and astrocytoma cells.", "content": "Biogenic amines in cultured neuroblastoma and astrocytoma cells. The presence of biogenic amines in cultured cells of mouse neuroblastoma C-1300 (clone NB-2a) was suggested by fluorescence-microscope histochemistry. Incubation in media containing L-[(14)C]tyrosine and L-[(14)C]tryptophan for 24 h, followed by high-voltage electrophoresis, radiochromatogram scanning, and scintillation counting, confirmed the presence of [(14)C]dopamine, [(14)C]norepinephrine, [(14)C]epinephrine, [(14)C]serotonin, [(14)C]tyramine, and [(14)C]octopamine. Dopamine, norepinephrine, epinephrine, and serotonin were demonstrated spectrophotofluorometrically in concentrations, expressed as micrograms amine per milligram protein, of 1.19, 0.027, 0.038, and 0.148, respectively, for cells in a stationary growth phase. Fluorescence-microscope histochemistry also suggested the presence of biogenic amines in cultured astrocytoma cells (cell line C6). Spectrophotofluorometric assay of cells in a stationary growth phase demonstrated intracellular dopamine, norepinephrine, epinephrine, and serotonin in concentrations significantly lower than those of neuroblastoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370924"}
{"pmid": "4370927", "title": "Content of adenosine 3'-5'-cyclic monophosphate in the pancreatic islets of mice with a hereditary defect of insulin secretion.", "content": "Content of adenosine 3'-5'-cyclic monophosphate in the pancreatic islets of mice with a hereditary defect of insulin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370927"}
{"pmid": "4370929", "title": "Segmental and lobar atrophy of the liver.", "content": "Segmental and lobar atrophy of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370929"}
{"pmid": "4370930", "title": "Carpenter syndrome--acrocephalopolysyndactyly type II.", "content": "Carpenter syndrome--acrocephalopolysyndactyly type II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370930"}
{"pmid": "4370931", "title": "Sequential renal lipid changes in weanling rats fed a choline-deficient diet.", "content": "Sequential renal lipid changes in weanling rats fed a choline-deficient diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370931"}
{"pmid": "4370932", "title": "Concentration of enteric viruses from water with lettuce extract.", "content": "Concentration of enteric viruses from water with lettuce extract. A method for recovering enteroviruses, adenovirus, and reovirus from water with lettuce extract is described. Lettuce extract at pH 8.5 was added to the sample and the pH was reduced stepwise with hydrochloric acid to 4.0 to 4.5. The flocculent lettuce-extract particles, and adsorbed virus, were readily removed from solution by low-speed centrifugation. Electron microscopy suggests that, under conditions suitable for adsorption, virus particles are coated with the lettuce-extract colloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370932"}
{"pmid": "4370933", "title": "The enzymology of short-chain fatty acyl-coenzyme A synthetase from seeds of Pinus radiata. Kinetic studies and a proposed reaction mechanism.", "content": "The enzymology of short-chain fatty acyl-coenzyme A synthetase from seeds of Pinus radiata. Kinetic studies and a proposed reaction mechanism. 1. Short-chain fatty acyl-CoA synthetase from seeds of Pinus radiata was examined by acetate- and propionate-dependent PP(i)-ATP exchange. Reaction mixtures came to equilibrium almost instantly as judged by rates of exchange and analysis of an incubation mixture. 2. The activity of the enzyme was correlated with the concentration of MgP(2)O(7) (2-) but not with the concentration of Mg(2+), as judged by PP(i)-ATP exchange and fatty acyl AMP-dependent synthesis of ATP in the presence of PP(i). In PP(i)-ATP exchange assays, no clear relationship between activity and any single species of ATP was apparent. 3. High concentrations of fatty acid inhibited PP(i)-ATP exchange. PP(i)-dATP exchange was less than PP(i)-ATP exchange at low concentrations of fatty acid, but at higher concentrations PP(i)-dATP exchange exceeded PP(i)-ATP exchange. The rate of synthesis of fatty acyl-CoA in the presence of dATP was less than with ATP. 4. ATP and propionate inhibited the synthesis of ATP from propionyl-AMP and PP(i). The inhibition by ATP was competitive with respect to propionyl-AMP and non-competitive with respect to PP(i). The inhibition by propionate was non-competitive with respect to propionyl-AMP and PP(i). 5. AMP was a competitive inhibitor of propionyl-AMP-dependent synthesis of ATP and competitively inhibited propionate-dependent PP(i)-ATP exchange when ATP was the variable substrate. 6. It was concluded that the first partial reaction catalysed by the enzyme is ordered; ATP is the first substrate to react with the enzyme and PP(i) is probably the only product released.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370933"}
{"pmid": "4370935", "title": "Stereospecific (3H)(minus)-alprenolol binding sites, beta-adrenergic receptors and adenylate cyclase.", "content": "Stereospecific (3H)(minus)-alprenolol binding sites, beta-adrenergic receptors and adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370935"}
{"pmid": "4370936", "title": "Stereotactic anterior cingulate lesions for persistent pain: a report on 68 cases.", "content": "Stereotactic anterior cingulate lesions for persistent pain: a report on 68 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370936"}
{"pmid": "4370934", "title": "Proteolytic processing in the biosynthesis of insulin and other proteins.", "content": "Proteolytic processing in the biosynthesis of insulin and other proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370934"}
{"pmid": "4370938", "title": "Susceptibility of human gingival cells to some animal viruses.", "content": "Susceptibility of human gingival cells to some animal viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370938"}
{"pmid": "4370937", "title": "Nucleotide sequence of tRNA Cys from baker's yeast.", "content": "Nucleotide sequence of tRNA Cys from baker's yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370937"}
{"pmid": "4370940", "title": "Cancer in immunosuppressed experimental animals and human patients.", "content": "Cancer in immunosuppressed experimental animals and human patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370940"}
{"pmid": "4370941", "title": "Cancer risk in ulcerative colitis: its independence of luminal factors.", "content": "Cancer risk in ulcerative colitis: its independence of luminal factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370941"}
{"pmid": "4370942", "title": "Cancer- and organ-specificity of the carcinoembryonic antigen.", "content": "Cancer- and organ-specificity of the carcinoembryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370942"}
{"pmid": "4370944", "title": "Letter: Accurate quantitative estimation of lactate in whole blood.", "content": "Letter: Accurate quantitative estimation of lactate in whole blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370944"}
{"pmid": "4370945", "title": "Letter: Cyclic AMP and cyclic GMP in gastric acid secretion.", "content": "Letter: Cyclic AMP and cyclic GMP in gastric acid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370945"}
{"pmid": "4370943", "title": "Letter: A newly recognized inherited syndrome of dwarfism, craniosynostosis, retinitis pigmentosa, and multiple congenital malformations.", "content": "Letter: A newly recognized inherited syndrome of dwarfism, craniosynostosis, retinitis pigmentosa, and multiple congenital malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370943"}
{"pmid": "4370947", "title": "Letter: Hematologic and biochemical profiles in normal Demoiselle cranes.", "content": "Letter: Hematologic and biochemical profiles in normal Demoiselle cranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370947"}
{"pmid": "4370946", "title": "Letter: Cytomegalovirus and penta X syndrome.", "content": "Letter: Cytomegalovirus and penta X syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370946"}
{"pmid": "4370948", "title": "Letter: Interference by antibiotics in amino acid assays.", "content": "Letter: Interference by antibiotics in amino acid assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370948"}
{"pmid": "4370949", "title": "Letter: Lead and intelligence.", "content": "Letter: Lead and intelligence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370949"}
{"pmid": "4370950", "title": "Letter: Nephroblastoma--genetic aspects.", "content": "Letter: Nephroblastoma--genetic aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370950"}
{"pmid": "4370951", "title": "Letter: Nephrotic syndrome with oat-cell carcinoma.", "content": "Letter: Nephrotic syndrome with oat-cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370951"}
{"pmid": "4370952", "title": "Letter: Prostaglandins in renal venous blood of essential hypertensive patients.", "content": "Letter: Prostaglandins in renal venous blood of essential hypertensive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370952"}
{"pmid": "4370953", "title": "Letter: Regulation of aldosterone biosynthesis by \"angiotensin III\".", "content": "Letter: Regulation of aldosterone biosynthesis by \"angiotensin III\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370953"}
{"pmid": "4370954", "title": "Letter: The dynamic voltage-transfer function for rod-bipolar cell transmission.", "content": "Letter: The dynamic voltage-transfer function for rod-bipolar cell transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370954"}
{"pmid": "4370955", "title": "Letter: Transmission of feline leukemia.", "content": "Letter: Transmission of feline leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370955"}
{"pmid": "4370956", "title": "Letter: Zoster in three children in family.", "content": "Letter: Zoster in three children in family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370956"}
{"pmid": "4370957", "title": "Cooperativity in the inhibition of oxidative phosphorylation by chlorophenoxyisobutyrate.", "content": "Cooperativity in the inhibition of oxidative phosphorylation by chlorophenoxyisobutyrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370957"}
{"pmid": "4370959", "title": "Temperature-sensitive DNA polymerase from Rous sarcoma virus mutants.", "content": "Temperature-sensitive DNA polymerase from Rous sarcoma virus mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370959"}
{"pmid": "4370958", "title": "Temperature-sensitive mutants of vesicular stomatitis virus: comparison of the in vitro RNA polymerase defects of group I and group IV mutants.", "content": "Temperature-sensitive mutants of vesicular stomatitis virus: comparison of the in vitro RNA polymerase defects of group I and group IV mutants. When tested in vitro, certain temperature-sensitive (ts) mutants of vesicular stomatitis virus (VSV) belonging to complementation groups I and IV appear to have defects in the virion-bound polymerase. To obtain further information concerning the nature of these defects, representative mutants were dissociated by the method of S. Emerson and R. Wagner (1972), and their supernatant (S) and pellet (P) fractions were tested for transcriptase activity when combined with the P and S fractions, respectively, of VSV-HR virions. It was found that the S fractions from group I mutants tsW4, 11, 14, 15, and 28 were defective in transcriptase activity, whereas their P fractions were as active as those of VSV-HR. On the other hand, the P fraction derived from virions of the group IV mutant tsW16B showed reduced activity at 25 C and very little activity at 38 C. These results suggest that our group I mutants, like those examined by D. Hunt and R. Wagner (1974), have a defect in the soluble transcriptase enzyme, whereas mutant tsW16B (group IV) has a defect in a sedimentable component required for transcriptase activity, possibly in the ribonucleoprotein template.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370958"}
{"pmid": "4370960", "title": "Differences in choroid plexus concentration of pertechnetate produced by varying time of pertechnetate administration and brain imaging.", "content": "Differences in choroid plexus concentration of pertechnetate produced by varying time of pertechnetate administration and brain imaging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370960"}
{"pmid": "4370961", "title": "Different types of mutagenic effect of ethylmethanesulfonate on Drosophila melanogaster.", "content": "Different types of mutagenic effect of ethylmethanesulfonate on Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370961"}
{"pmid": "4370962", "title": "Differential activation of biologically distinguishable endogenous mouse type C RNA viruses: interaction with host cell regulatory factors.", "content": "Differential activation of biologically distinguishable endogenous mouse type C RNA viruses: interaction with host cell regulatory factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370962"}
{"pmid": "4370963", "title": "Differential diagnosis of tumors of the salivary glands with radioactive isotopes.", "content": "Differential diagnosis of tumors of the salivary glands with radioactive isotopes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370963"}
{"pmid": "4370965", "title": "Bacterial exoenzymes toxic for insects; proteinase and lecithinase.", "content": "Bacterial exoenzymes toxic for insects; proteinase and lecithinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370965"}
{"pmid": "4370966", "title": "Bacterial interference between strains of S. aureus.", "content": "Bacterial interference between strains of S. aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370966"}
{"pmid": "4370972", "title": "Epidermolysis in a case of severe cytomegalovirus infection.", "content": "Epidermolysis in a case of severe cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370972"}
{"pmid": "4370974", "title": "Concerning specificity of the influence of pentoxifylline on various cyclic AMP phosphodiesterases.", "content": "Concerning specificity of the influence of pentoxifylline on various cyclic AMP phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370974"}
{"pmid": "4370973", "title": "Pattern of osmium deposition in the parietal cells of the stomach.", "content": "Pattern of osmium deposition in the parietal cells of the stomach. Parietal cells of the stomach of the hamster show extensive amounts of dense material in a variety of organelles after prolonged exposure to a solution of osmium tetroxide. Conspicuous amounts of reduced osmium compounds are evident within the granular endoplasmic reticulum, perinuclear cisterna, and vesicular elements of the Golgi complex. Dense material is also apparent within cristae of the mitochondria, the surface coat of the microvilli of the intracellular canaliculus, and vesicular elements of the multivesicular bodies. Multivesicular bodies, containing numerous small osmiophilic elements, are often seen surrounding and/or in close contact with mitochondria. The proximity of the multivesicular bodies to the mitochondria appears to be related to an autophagic process involving degradation of mitochondria. The distribution and intensity of the precipitates within the organelles of the parietal cells vary in different regions of the gastric glands. The findings of this study emphasize that cell structures other than the Golgi complex may contain large concentrations of reduced osmium compounds after prolonged exposure to a solution of osmium tetroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370973"}
{"pmid": "4370975", "title": "Dispersion of central nervous system tumors. Correlation between clinical aspects and tissue culture studies.", "content": "Dispersion of central nervous system tumors. Correlation between clinical aspects and tissue culture studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370975"}
{"pmid": "4370977", "title": "Properties of a phosphoprotein phosphatase from bovine heart with activity on glycogen synthase, phosphorylase, and histone.", "content": "Properties of a phosphoprotein phosphatase from bovine heart with activity on glycogen synthase, phosphorylase, and histone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370977"}
{"pmid": "4370976", "title": "Properties and substrate specificity of some reactions catalysed by a short-chain fatty acyl-coenzyme A synthetase from seeds of Pinus radiata.", "content": "Properties and substrate specificity of some reactions catalysed by a short-chain fatty acyl-coenzyme A synthetase from seeds of Pinus radiata. 1. Crude extracts of seeds of Pinus radiata catalysed acetate-, propionate-, n-butyrate- and n-valerate-dependent PP(i)-ATP exchange in the presence of MgCl(2), which was apparently due to a single enzyme. Propionate was the preferred substrate. Crude extracts did not catalyse medium-chain or long-chain fatty acid-dependent exchange. 2. Ungerminated dry seeds contained short-chain fatty acyl-CoA synthetase activity. The activity per seed was approximately constant for 11 days after imbibition and then declined. The enzyme was located only in the female gametophyte tissue. 3. The synthetase was purified 70-fold. 4. Some properties of the enzyme were studied by [(32)P]PP(i)-ATP exchange. K(m) values for acetate, propionate, n-butyrate and n-valerate were 4.7, 0.21, 0.33 and 2.1mm respectively. Competition experiments between acetate and propionate demonstrated that only one enzyme was involved and confirmed that the affinity of the enzyme for propionate was greater than that for acetate. CoA inhibited fatty acid-dependent PP(i)-ATP exchange. The enzyme catalysed fatty acid-dependent [(32)P]PP(i)-dATP exchange. 5. The enzyme also catalysed the fatty acyl-AMP-dependent synthesis of [(32)P]ATP from [(32)P]PP(i). Apparent K(m) (acetyl-AMP) and apparent K(m) (propionyl-AMP) were 57mum and 7.5mum respectively. The reaction was inhibited by AMP and CoA. 6. Purified enzyme catalysed the synthesis of acetyl-CoA and propionyl-CoA. Apparent K(m) (acetate) and apparent K(m) (propionate) were 16mm and 7.5mm respectively. The rate of formation of acetyl-CoA was enhanced by pyrophosphatase. 7. It was concluded that fatty acyl adenylates are intermediates in the formation of the corresponding fatty acyl-CoA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370976"}
{"pmid": "4370978", "title": "Properties of 3-hydroxy-3-methylglutaryl coenzyme A reductase solubilized from rat liver and hepatoma.", "content": "Properties of 3-hydroxy-3-methylglutaryl coenzyme A reductase solubilized from rat liver and hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370978"}
{"pmid": "4370981", "title": "Herpes encephalitis therapeutic considerations.", "content": "Herpes encephalitis therapeutic considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370981"}
{"pmid": "4370982", "title": "Herpes encephalitis with catatonic stupor.", "content": "Herpes encephalitis with catatonic stupor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370982"}
{"pmid": "4370980", "title": "Glomerular beta-lipoprotein in childhood renal diseases.", "content": "Glomerular beta-lipoprotein in childhood renal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370980"}
{"pmid": "4370983", "title": "Herpes genitalis and aseptic meningitis.", "content": "Herpes genitalis and aseptic meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370983"}
{"pmid": "4370985", "title": "Herpes simplex lesions of the skin diagnosed by the immunofluorescence technique.", "content": "Herpes simplex lesions of the skin diagnosed by the immunofluorescence technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370985"}
{"pmid": "4370986", "title": "Herpes simplex virus and human cytomegalovirus replication in WI-38 cells. II. An ultrastructural study of viral penetration.", "content": "Herpes simplex virus and human cytomegalovirus replication in WI-38 cells. II. An ultrastructural study of viral penetration. An electron microscope study was carried out on the early minutes of herpes simplex virus (HSV) and cytomegalovirus (CMV) penetration into WI-38 cells. Both HSV and CMV entered cells either by fusion of the viral envelope with a limiting cell membrane, or via phagocytosis. Both fusion and phagocytosis occurred within 3 min after the initiation of penetration. After fusion, the naked capsids of CMV free in the cytoplasm became coated with a fine, fibrillar material. CMV capsids thus coated retained a well-defined and easily identifiable morphology until the eclipse of visible viral particles between 1 and 1.5 days postinfection. In contrast, naked HSV capsids free in the cytoplasm were never coated. Rather, within minutes after penetration, they assumed a rounded, less regular outline, and were no longer detectable by 90 to 120 min postinfection. The free naked capsids of both viruses appeared to migrate across the cytoplasm toward the nucleus and to become located near nuclear pores. Both HSV and CMV capsids reached the nucleus as early as 5 min after the initiation of penetration. No further interaction with the nucleus could be documented. Particles were also consistently identified in the Golgi region. Phagocytosed particles generally remained within phagosomes, where they appeared to be degraded. However, stages were identified in what is believed to be the escape of enveloped viruses from phagosomes into the cytoplasm via fusion of their envelope with the phagosomal membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370986"}
{"pmid": "4370987", "title": "Herpes virus latency in spinal ganglia of mice without illness.", "content": "Herpes virus latency in spinal ganglia of mice without illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370987"}
{"pmid": "4370988", "title": "Herpes viruses and oncogenesis.", "content": "Herpes viruses and oncogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370988"}
{"pmid": "4370989", "title": "Successful extraction of large intracaval isthmus of nephroblastoma.", "content": "Successful extraction of large intracaval isthmus of nephroblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370989"}
{"pmid": "4370984", "title": "Herpes genitalis and its relationship to cervical cancer.", "content": "Herpes genitalis and its relationship to cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370984"}
{"pmid": "4370990", "title": "Depression of cell-mediated immunity during acute infectious mononucleosis.", "content": "Depression of cell-mediated immunity during acute infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370990"}
{"pmid": "4370991", "title": "Depression of human monocyte chemotaxis by herpes simplex and influenza viruses.", "content": "Depression of human monocyte chemotaxis by herpes simplex and influenza viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370991"}
{"pmid": "4370992", "title": "Expression of purified mitochondrial poly(A)polymerase of hepatomas by an endogenous primer from liver..", "content": "Expression of purified mitochondrial poly(A)polymerase of hepatomas by an endogenous primer from liver..", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370992"}
{"pmid": "4370993", "title": "Progesterone and androgen receptors in non-flagellate germ cells of the rat testis.", "content": "Progesterone and androgen receptors in non-flagellate germ cells of the rat testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370993"}
{"pmid": "4370995", "title": "Nondestructive separation of rat liver rough microsomes into ribosomal and membranous components.", "content": "Nondestructive separation of rat liver rough microsomes into ribosomal and membranous components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370995"}
{"pmid": "4370996", "title": "Herpesvirus encephalitis and pulmonary sarcoidosis. A case report with necropsy findings.", "content": "Herpesvirus encephalitis and pulmonary sarcoidosis. A case report with necropsy findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370996"}
{"pmid": "4370994", "title": "Cholesteryl ester metabolism in tissue culture cells. I. Accumulation in Fu5AH rat hepatoma cells.", "content": "Cholesteryl ester metabolism in tissue culture cells. I. Accumulation in Fu5AH rat hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370994"}
{"pmid": "4370998", "title": "Competitive protein-binding radioassay of urinary cortisol.", "content": "Competitive protein-binding radioassay of urinary cortisol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370998"}
{"pmid": "4370999", "title": "Pasteur effect and phosphofructokinase.", "content": "Pasteur effect and phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4370999"}
{"pmid": "4371000", "title": "EEG evaluation of a sleep recorder.", "content": "EEG evaluation of a sleep recorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371000"}
{"pmid": "4371002", "title": "Purification and properties of an extracellular acid ribonuclease from Penicillium janthinellum.", "content": "Purification and properties of an extracellular acid ribonuclease from Penicillium janthinellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371002"}
{"pmid": "4371004", "title": "Modification of diphtheria toxin by NAD.", "content": "Modification of diphtheria toxin by NAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371004"}
{"pmid": "4371003", "title": "Purification and regulatory properties of fructose 1,6-diphosphatase from Hydrogenomonas eutropha.", "content": "Purification and regulatory properties of fructose 1,6-diphosphatase from Hydrogenomonas eutropha. Fructose diphosphatase of Hydrogenomonas eutropha H 16, produced during autotrophic growth, was purified 247-fold from extracts of cells. The molecular weight of the enzyme was estimated to be 170,000. The enzyme showed a pH optimum of 8.5 in both crude extracts and purified preparation. The shape of the pH curve was not changed in the presence of ethylenediaminetetraacetic acid. The enzyme required Mg(2+) for activity. The MgCl(2) saturation curve was sigmoidal and the degree of positive cooperativity increased at lower fructose diphosphate concentrations. Mn(2+) can replace Mg(2+), but maximal activity was lower than that observed with Mg(2+) and the optimal concentration range was narrow. The fructose diphosphate curve was also sigmoidal. The purified enzyme also hydrolyzed sedoheptulose diphosphate but at a much lower rate than fructose diphosphate. The enzyme was not inhibited by adenosine 5'-monophosphate but was inhibited by ribulose 5-phosphate and adenosine 5'-triphosphate. Adenosine 5'-triphosphate did not affect the degree of cooperativity among the sites for fructose diphosphate. The inhibition by adenosine 5'-triphosphate was mixed and by ribulose 5-phosphate was noncompetitive. An attempt was made to correlate the properties of fructose diphosphatase from H. eutropha with its physiological role during autotrophic growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371003"}
{"pmid": "4371006", "title": "The fine structure of the ovarian follicle of Alloteuthis subulata Lam. (Mollusca, Cephalopoda).", "content": "The fine structure of the ovarian follicle of Alloteuthis subulata Lam. (Mollusca, Cephalopoda).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371006"}
{"pmid": "4371005", "title": "The fine structure of the lutein cells in the blue fox (Alopex lagopus) with special reference to the secretory activity during pregnancy.", "content": "The fine structure of the lutein cells in the blue fox (Alopex lagopus) with special reference to the secretory activity during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371005"}
{"pmid": "4371008", "title": "The foot-and-mouth disease virus subtype variants in Kenya.", "content": "The foot-and-mouth disease virus subtype variants in Kenya. The subtype variants found in Kenya in the past ten years have been studied. The type O and type SAT 2 subtypes have a distinct geographical distribution which appears to be associated with livestock movement patterns. The type A viruses have a greater tendency to antigenic variation and their geographical distribution is less distinct. In type C only minor differences exist between the three viruses studied.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371008"}
{"pmid": "4371011", "title": "Wakefulness and REM sleep in human neonates.", "content": "Wakefulness and REM sleep in human neonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371011"}
{"pmid": "4371001", "title": "The eye and its disorders. 29. Diseases of the visual pathways.", "content": "The eye and its disorders. 29. Diseases of the visual pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371001"}
{"pmid": "4371012", "title": "Rat gastric mucosal cAMP following cholinergic and histamine stimulation.", "content": "Rat gastric mucosal cAMP following cholinergic and histamine stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371012"}
{"pmid": "4371014", "title": "Cytogenetic study of primary tumors induced in the golden hamster by chemical and viral agents. Communication II. Karyotypic characteristics of tumors induced by the simian virus 40 (SV40) and the combined action of virus and 7,12-dimethylbenzanthracene.", "content": "Cytogenetic study of primary tumors induced in the golden hamster by chemical and viral agents. Communication II. Karyotypic characteristics of tumors induced by the simian virus 40 (SV40) and the combined action of virus and 7,12-dimethylbenzanthracene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371014"}
{"pmid": "4371013", "title": "The general febrile respiratory form of infectious bovine rhinotracheitis in calves.", "content": "The general febrile respiratory form of infectious bovine rhinotracheitis in calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371013"}
{"pmid": "4371007", "title": "The flower pot technique of rapid eye movement (REM) sleep deprivation.", "content": "The flower pot technique of rapid eye movement (REM) sleep deprivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371007"}
{"pmid": "4371015", "title": "Antigenic makeup of subcellular fractions of Trypanosoma cruzi.", "content": "Antigenic makeup of subcellular fractions of Trypanosoma cruzi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371015"}
{"pmid": "4371017", "title": "Changes during development of mouse brain in the activities and subcellular distributions of creatine and adenylate kinases.", "content": "Changes during development of mouse brain in the activities and subcellular distributions of creatine and adenylate kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371017"}
{"pmid": "4371018", "title": "Changes in intra-ovarian pressure in woman following the administration of luteinizing hormone-releasing hormone LH-FSH).", "content": "Changes in intra-ovarian pressure in woman following the administration of luteinizing hormone-releasing hormone LH-FSH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371018"}
{"pmid": "4371020", "title": "Hypoglycemia: pathogenesis, diagnosis and treatment.", "content": "Hypoglycemia: pathogenesis, diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371020"}
{"pmid": "4371021", "title": "Recognition by electrophoretic localisation of the extracellular products of selected strains of staphylococci.", "content": "Recognition by electrophoretic localisation of the extracellular products of selected strains of staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371021"}
{"pmid": "4371022", "title": "Assignment of the gene for galactokinase to human chromosome 17 and its regional localisation to band q21-22.", "content": "Assignment of the gene for galactokinase to human chromosome 17 and its regional localisation to band q21-22.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371022"}
{"pmid": "4371024", "title": "Antagonism of morphine by beta-melanocyte-stimulating hormone and by tetracosactin.", "content": "Antagonism of morphine by beta-melanocyte-stimulating hormone and by tetracosactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371024"}
{"pmid": "4371023", "title": "Antagonism of dopamine-mediated inhibition in the nigro-striatal pathway: a mode of action of some catatonia-inducing drugs.", "content": "Antagonism of dopamine-mediated inhibition in the nigro-striatal pathway: a mode of action of some catatonia-inducing drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371023"}
{"pmid": "4371025", "title": "Antagonistic effect of methadone on steroidogenesis and the adenylate cyclase system in isolated rat adrenocortical cells.", "content": "Antagonistic effect of methadone on steroidogenesis and the adenylate cyclase system in isolated rat adrenocortical cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371025"}
{"pmid": "4371027", "title": "Lymph node metastasis as first manifestation of glioblastoma. Case report.", "content": "Lymph node metastasis as first manifestation of glioblastoma. Case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371027"}
{"pmid": "4371026", "title": "Energy-linked reactions in photosynthetic bacteria. IX. Pi-PPi exchange in Rhodospirillum rubrum.", "content": "Energy-linked reactions in photosynthetic bacteria. IX. Pi-PPi exchange in Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371026"}
{"pmid": "4371032", "title": "On the electron transfer reaction between ferricytochrome c and ferrohexacyanide in the pH range 5 to 7.", "content": "On the electron transfer reaction between ferricytochrome c and ferrohexacyanide in the pH range 5 to 7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371032"}
{"pmid": "4371034", "title": "Is the neurotransmitter system abnormal in multiple sclerosis?", "content": "Is the neurotransmitter system abnormal in multiple sclerosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371034"}
{"pmid": "4371035", "title": "On the origin of the genes for neoplasia: G.H.A. Clowes memorial lecture.", "content": "On the origin of the genes for neoplasia: G.H.A. Clowes memorial lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371035"}
{"pmid": "4371033", "title": "On the extracellular synthesis of adenosine triphosphate by mammalian cells.", "content": "On the extracellular synthesis of adenosine triphosphate by mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371033"}
{"pmid": "4371036", "title": "On the problem of the origin of nerve terminals in the sympathetic ganglia.", "content": "On the problem of the origin of nerve terminals in the sympathetic ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371036"}
{"pmid": "4371037", "title": "On the question of the primary acceptor in bacterial photosynthesis:manganese substituting for iron in reaction centers of Rhodopseudomonas spheroides R-26.", "content": "On the question of the primary acceptor in bacterial photosynthesis:manganese substituting for iron in reaction centers of Rhodopseudomonas spheroides R-26.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371037"}
{"pmid": "4371038", "title": "On the relationship between cell division and cyclic adenosine-3',5'-monophosphate in Escherichia coli.", "content": "On the relationship between cell division and cyclic adenosine-3',5'-monophosphate in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371038"}
{"pmid": "4371031", "title": "On the association of some dermatoses with South American pemphigus foliaceus.", "content": "On the association of some dermatoses with South American pemphigus foliaceus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371031"}
{"pmid": "4371040", "title": "Epithelial inclusions in the vas deferens: an electron microscopic study.", "content": "Epithelial inclusions in the vas deferens: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371040"}
{"pmid": "4371039", "title": "On the ultrastructure of the rat anococcygeus muscle.", "content": "On the ultrastructure of the rat anococcygeus muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371039"}
{"pmid": "4371041", "title": "Biochemical and endocrine differences between normotensive and spontaneously hypertensive rats.", "content": "Biochemical and endocrine differences between normotensive and spontaneously hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371041"}
{"pmid": "4371044", "title": "Further studies on postsynaptic potential in masseteric motoneuron.", "content": "Further studies on postsynaptic potential in masseteric motoneuron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371044"}
{"pmid": "4371042", "title": "Biochemical and morphological characterization of azurophil and specific granules of human neutrophilic polymorphonuclear leukocytes.", "content": "Biochemical and morphological characterization of azurophil and specific granules of human neutrophilic polymorphonuclear leukocytes. Postnuclear supernates from homogenates of purified neutrophil polymorphonuclear leukocytes (PMNs) from human blood were fractionated by zonal sedimentation and isopycnic equilibration in sucrose gradients. The fractions were characterized biochemically by measuring protein content and the activities of eight enzymes. Selected fractions were further analyzed by electron microscopy. In both centrifugation systems, azurophil and specific granules could be resolved almost completely. Azurophil granules sediment three to four times faster than the specifics and have an average density of 1.23. They contain all the peroxidase of the cells, large portions of four lysosomal hydrolases, and about half of the total lysozyme, and therefore appear to be, in biochemical terms, very similar to the azurophil granules of rabbit PMNs. The specific granules, which have an average density of 1.19, contain the remaining half of the lysozyme but appear to be free of the other components of the azurophil granules, and of alkaline phosphatase. Isopycnic equilibration disclosed a minor lysosomal population, which strongly overlaps the specific granules, and made possible the identification of a membrane-fraction which is characterized by the presence of the thiol-sensitive acid 4-nitrophenyl phosphatase and of alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371042"}
{"pmid": "4371046", "title": "Synthesis of simian virus 40 DNA in isolated nuclei.", "content": "Synthesis of simian virus 40 DNA in isolated nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371046"}
{"pmid": "4371045", "title": "Synthesis and secretion of fibrinogen and albumin by isolated rat hepatocytes.", "content": "Synthesis and secretion of fibrinogen and albumin by isolated rat hepatocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371045"}
{"pmid": "4371047", "title": "Synthesis of some new semisynthetic penicillins.", "content": "Synthesis of some new semisynthetic penicillins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371047"}
{"pmid": "4371050", "title": "Morphological and cytological effects of carbenicillin on Pseudomonas pseudomallei.", "content": "Morphological and cytological effects of carbenicillin on Pseudomonas pseudomallei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371050"}
{"pmid": "4371051", "title": "Psychological aspects of cardiac surgery. Psychiatric grand rounds.", "content": "Psychological aspects of cardiac surgery. Psychiatric grand rounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371051"}
{"pmid": "4371052", "title": "Morphology and X-ray sensitivity of rat glial cells after cytochalasin B treatment.", "content": "Morphology and X-ray sensitivity of rat glial cells after cytochalasin B treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371052"}
{"pmid": "4371053", "title": "Morphology of the aging brain, human and animal.", "content": "Morphology of the aging brain, human and animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371053"}
{"pmid": "4371054", "title": "N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture.", "content": "N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371054"}
{"pmid": "4371055", "title": "Psychotropic drugs and some enzymes of energy metabolism.", "content": "Psychotropic drugs and some enzymes of energy metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371055"}
{"pmid": "4371057", "title": "Prophylactic use of antibiotics in preventing bovine respiratory disease complex.", "content": "Prophylactic use of antibiotics in preventing bovine respiratory disease complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371057"}
{"pmid": "4371059", "title": "Staphylococcal sphingomyelinase (beta-hemolysin).", "content": "Staphylococcal sphingomyelinase (beta-hemolysin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371059"}
{"pmid": "4371058", "title": "Staphylococcal sphingomyelinase (beta-hemolysin).", "content": "Staphylococcal sphingomyelinase (beta-hemolysin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371058"}
{"pmid": "4371060", "title": "The hyperthermic effect of intracerebroventricular cholera enterotoxin in the unanaesthetized cat.", "content": "The hyperthermic effect of intracerebroventricular cholera enterotoxin in the unanaesthetized cat. 1. Cholera enterotoxin was used to evaluate a possible role of endogenous cyclic AMP in production of hyperthermia. Injection of purified toxin (0.10-1.0 mug in 0.10 ml.) into the lateral cerebral ventricle of unanaesthetized cats caused dose-related hyperthermic responses. Heating the toxin for 40 min at 90 degrees C abolished its hyperthermic activity.2. Intraventricular administration of dibutyryl cyclic AMP (250-1000 mug) also caused hyperthermia which, however, was preceded by transient periods of hypothermia and/or excitation in about half of the tests.3. Paracetamol, indomethacin and sodium salicylate inhibited hyperthermic responses to cholera enterotoxin. Paracetamol and indomethacin also inhibited hyperthermia induced by dibutyryl cyclic AMP (sodium salicylate was not tested).4. It is likely that the hyperthermic effect of cholera enterotoxin in the cat is mediated via endogenous cyclic AMP and that the antipyretics inhibit this effect by an action subsequent to the increase in cyclic AMP.5. It is unlikely that prostaglandin-induced hyperthermia in the cat is mediated via cyclic AMP since these antipyretics do not inhibit this response to prostaglandin E(1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371060"}
{"pmid": "4371062", "title": "Cardiac hypertrophy in spontaneously hypertensive rats.", "content": "Cardiac hypertrophy in spontaneously hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371062"}
{"pmid": "4371061", "title": "The hypothalamo-hypophysial system of the lamprey, Lampetra fluviatilis L. I. the neuohypophysis.", "content": "The hypothalamo-hypophysial system of the lamprey, Lampetra fluviatilis L. I. the neuohypophysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371061"}
{"pmid": "4371063", "title": "A trial of corticotrophin gelatin injection in acute optic neuritis.", "content": "A trial of corticotrophin gelatin injection in acute optic neuritis. The effect of a 30 day course of corticotrophin gelatin injections on the natural history of acute unilateral optic neuritis in 27 patients is reported. A further 27 patients received inert injections in a double-blind control. Measurements were made on visual acuity, visual field, macular threshold, and colour vision, and the development of optic atrophy and other neurological episodes was recorded. No significant differences were found between treated and control groups at intervals up to two years from the start of the trial. The criteria for inclusion of patients are given and it is concluded that corticotrophin has no effect on the natural history of the condition as defined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371063"}
{"pmid": "4371065", "title": "Ovarian hilus-cell tumours: their varying presentations.", "content": "Ovarian hilus-cell tumours: their varying presentations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371065"}
{"pmid": "4371066", "title": "Ovarian neoplasms at the Chelsea Hospital.", "content": "Ovarian neoplasms at the Chelsea Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371066"}
{"pmid": "4371068", "title": "Possible higher valence states of cytochrome P-450 during oxidative reactions.", "content": "Possible higher valence states of cytochrome P-450 during oxidative reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371068"}
{"pmid": "4371067", "title": "Amebiasis in a mental institution: serologic and epidemiologic studies.", "content": "Amebiasis in a mental institution: serologic and epidemiologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371067"}
{"pmid": "4371069", "title": "A cribriform cylindroma with metastases.", "content": "A cribriform cylindroma with metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371069"}
{"pmid": "4371071", "title": "Steric and electrostatic interactions in reactions of carbohydrates. III. Direct displacement of the C-2 sulfonate of methyl 4,6-o-benzylidene-3-o-methyl-2-o-methylsulfonyl-beta-d-gluco-and-mannopyranosides.", "content": "Steric and electrostatic interactions in reactions of carbohydrates. III. Direct displacement of the C-2 sulfonate of methyl 4,6-o-benzylidene-3-o-methyl-2-o-methylsulfonyl-beta-d-gluco-and-mannopyranosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371071"}
{"pmid": "4371072", "title": "Cyclic AMP levels in Phycomyces during a response to light.", "content": "Cyclic AMP levels in Phycomyces during a response to light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371072"}
{"pmid": "4371070", "title": "Cyclic adenosine monophosphate-dependent phosphorylation of specific fat cell membrane proteins by an endogenous membrane-bound protein kinase. Possible involvement in the regulation of insulin-stimulated glucose transport.", "content": "Cyclic adenosine monophosphate-dependent phosphorylation of specific fat cell membrane proteins by an endogenous membrane-bound protein kinase. Possible involvement in the regulation of insulin-stimulated glucose transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371070"}
{"pmid": "4371073", "title": "Cyclic AMP mediates the concanavalin A agglutinability of mouse fibroblasts.", "content": "Cyclic AMP mediates the concanavalin A agglutinability of mouse fibroblasts. We have devised a quantitative way to measure the agglutination of cells which utilizes the size discrimination feature of an automatic particle counter. With this method we have studied the agglutinability by concanavalin A of 3T3 cells, a mutant of 3T3 cells (3T3cAMP(tcs)) in which cyclic AMP levels fall when the cells are subjected to temperature change or fresh serum, and L929 cells. We find with 3T3cAMP(tcs) cells that low levels of cyclic AMP correlate with increased agglutinability and that high levels of cyclic AMP correlate with decreased agglutinability. Prior treatment of these cells with a cyclic AMP phosphodiesterase inhibitor or Bt(2)cAMP blocks the increase in agglutinability induced by temperature change. When 3T3 cells are treated with fresh serum, their agglutinability also increases although to a much smaller extent than with 3T3cAMP(tcs) cells. Cells change their agglutinability very rapidly. Treatment of L929 cells for 15 min with 1-methyl-3-isobutyl xanthine at 1 mM decreases their agglutinability to the level of normal 3T3 cells. We conclude that in normal and transformed cells the level of cyclic AMP regulates agglutinability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371073"}
{"pmid": "4371074", "title": "Cyclic GMP and cyclic AMP levels in normal and transformed fibroblasts.", "content": "Cyclic GMP and cyclic AMP levels in normal and transformed fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371074"}
{"pmid": "4371076", "title": "Surgical aspects of amebiasis.", "content": "Surgical aspects of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371076"}
{"pmid": "4371075", "title": "Clinical antitumor activity and toxicity of streptozotocin (NSC-85998).", "content": "Clinical antitumor activity and toxicity of streptozotocin (NSC-85998).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371075"}
{"pmid": "4371064", "title": "[Facial paralysis of unknown origin. Testing for a viral etiology by antibody measurement].", "content": "[Facial paralysis of unknown origin. Testing for a viral etiology by antibody measurement].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371064"}
{"pmid": "4371077", "title": "Atypical blood lymphocytes in sarcoidosis: morphology, cytochemistry, and membrane properties.", "content": "Atypical blood lymphocytes in sarcoidosis: morphology, cytochemistry, and membrane properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371077"}
{"pmid": "4371079", "title": "Physical properties of a dog liver and kidney cytosol protein that binds thyroid hormone.", "content": "Physical properties of a dog liver and kidney cytosol protein that binds thyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371079"}
{"pmid": "4371080", "title": "Physical protein regulation of adenylate kinases from muscle, liver, and hepatoma.", "content": "Physical protein regulation of adenylate kinases from muscle, liver, and hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371080"}
{"pmid": "4371078", "title": "Atypical demyelinating disease.", "content": "Atypical demyelinating disease. A 17 year old girl died after an illness characterized by progressive mental deterioration and severe myoclonic jerks. Extensive pathological, virological, and immunological studies failed to support the diagnosis of subacute sclerosing panencephalitis but were compatible with disseminated demyelinating disease. The spinal fluid was positive for measles virus antibodies when examined by the fluorescent antibody technique, by complement fixation, and by haemagglutination inhibition tests, but the antibody titres were not high. The concentration of vaccinia antibody in the serum was consistent with that found in the general population and none was detected in the spinal fluid. Animal and tissue culture studies failed to disclose a viral agent, but pathological sections revealed perivascular cellular infiltration, demyelination, rare inclusion bodies, and multinucleated giant cells. Although these studies were not definitive, a record of procedures used and results obtained, both positive and negative, may be helpful to other investigators interested in defining more accurately the clinical features and the pathogenesis of these diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371078"}
{"pmid": "4371081", "title": "Chemical structure of a modification of the Escherichia coli ribonucleic acid polymerase alpha polypeptides induced by bacteriophage T4 infection.", "content": "Chemical structure of a modification of the Escherichia coli ribonucleic acid polymerase alpha polypeptides induced by bacteriophage T4 infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371081"}
{"pmid": "4371083", "title": "Clinical use of renin determinations.", "content": "Clinical use of renin determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371083"}
{"pmid": "4371082", "title": "Chemical synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3 an analog of 1alpha,25-(OH)2-D3, the active form of vitamin D3.", "content": "Chemical synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3 an analog of 1alpha,25-(OH)2-D3, the active form of vitamin D3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371082"}
{"pmid": "4371084", "title": "Application of a vidicon spectrometer for simultaneous flame-emission analysis for sodium and potassium in serum.", "content": "Application of a vidicon spectrometer for simultaneous flame-emission analysis for sodium and potassium in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371084"}
{"pmid": "4371085", "title": "Application of immune electron microscopy to the study of the antigenic relationships between three new human papovaviruses.", "content": "Application of immune electron microscopy to the study of the antigenic relationships between three new human papovaviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371085"}
{"pmid": "4371087", "title": "Corticosteroids: a direct effect at the neuromuscular junction.", "content": "Corticosteroids: a direct effect at the neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371087"}
{"pmid": "4371088", "title": "Corticotropin release during ECT in man.", "content": "Corticotropin release during ECT in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371088"}
{"pmid": "4371091", "title": "Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.", "content": "Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371091"}
{"pmid": "4371092", "title": "President's address. Myasthenia gravis.", "content": "President's address. Myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371092"}
{"pmid": "4371094", "title": "Studies of the regulation of colicin Ib synthesis. II. The synthesis of col Ib-P9 specific RNA in vivo.", "content": "Studies of the regulation of colicin Ib synthesis. II. The synthesis of col Ib-P9 specific RNA in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371094"}
{"pmid": "4371093", "title": "Studies of serum lipoprotein concentrations in children: preliminary report.", "content": "Studies of serum lipoprotein concentrations in children: preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371093"}
{"pmid": "4371095", "title": "Studies of NAD(H) conformations in solution: a new method using the PMR spectra of cobalt ion-dinucleotide complexes.", "content": "Studies of NAD(H) conformations in solution: a new method using the PMR spectra of cobalt ion-dinucleotide complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371095"}
{"pmid": "4371089", "title": "Prediction of the secondary structure of proteins using the helix-coil transition theory.", "content": "Prediction of the secondary structure of proteins using the helix-coil transition theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371089"}
{"pmid": "4371096", "title": "Studies on the diagnostic value of an immunofluorescence test for EB virus-specific IgM.", "content": "Studies on the diagnostic value of an immunofluorescence test for EB virus-specific IgM. A modification of the test for EB virus/IgM introduced by Schmitz and Scherer (1972) is described. It is simple and gives reproducible results.EB virus/IgM was demonstrated in all but one case of infectious mononucleosis and in students with minor illness shown to have acquired EB virus/IgG recently. Unlike the EB virus/IgG, the IgM disappears within a few months. Although the Paul-Bunnell-Davidsohn test is still the test of choice for the diagnosis of infectious mononucleosis, the EB virus/IgM test could be useful to establish a diagnosis of current or recent EB virus infection where the Paul-Bunnell-Davidsohn test was negative or equivocal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371096"}
{"pmid": "4371097", "title": "Studies on the effects of acetylcholine, epinephrine, dibutyryl cyclic adenosine monophosphate, theophylline, and calcium on the synthesis of myoglobin in muscle cell cultures estimated by radioimmunoassay.", "content": "Studies on the effects of acetylcholine, epinephrine, dibutyryl cyclic adenosine monophosphate, theophylline, and calcium on the synthesis of myoglobin in muscle cell cultures estimated by radioimmunoassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371097"}
{"pmid": "4371098", "title": "Studies on the growth and changes in metabolism of rats fed on carbohydrate-deficient fatty acid-based diets supplemented with graded levels of maize starch.", "content": "Studies on the growth and changes in metabolism of rats fed on carbohydrate-deficient fatty acid-based diets supplemented with graded levels of maize starch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371098"}
{"pmid": "4371099", "title": "Studies on the in vitro adenylation of RNA by vesicular stomatitis virus.", "content": "Studies on the in vitro adenylation of RNA by vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371099"}
{"pmid": "4371101", "title": "Studies on the mechanism of deacylation of aminoacyl-tRNAs by aminoacyl-tRNA synthetases in the absence of adenosine monophosphate and pyrophosphate.", "content": "Studies on the mechanism of deacylation of aminoacyl-tRNAs by aminoacyl-tRNA synthetases in the absence of adenosine monophosphate and pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371101"}
{"pmid": "4371102", "title": "Studies on the stability of the hemagglutinating antibody of Entamoeba histolytica.", "content": "Studies on the stability of the hemagglutinating antibody of Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371102"}
{"pmid": "4371100", "title": "Studies on the inhibition of RNA synthesis by phalloidin in primary cultures of fetal cells.", "content": "Studies on the inhibition of RNA synthesis by phalloidin in primary cultures of fetal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371100"}
{"pmid": "4371103", "title": "Studies on the structure-activity relationships of synthetic LHRH analogs.", "content": "Studies on the structure-activity relationships of synthetic LHRH analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371103"}
{"pmid": "4371104", "title": "Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine(BL 191). I. Cyclic 3',5'-nucleotide phosphodiesterase (PDE) and the inhibitory effect of BL 191 on PDE in rat brain and heart.", "content": "Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine(BL 191). I. Cyclic 3',5'-nucleotide phosphodiesterase (PDE) and the inhibitory effect of BL 191 on PDE in rat brain and heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371104"}
{"pmid": "4371105", "title": "Specific binding of growth hormone to thymocytes.", "content": "Specific binding of growth hormone to thymocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371105"}
{"pmid": "4371106", "title": "Amplification of a circular segment of SV40 DNA.", "content": "Amplification of a circular segment of SV40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371106"}
{"pmid": "4371107", "title": "Calcification of selected strains of Streptococcus mutans and Streptococcus sanguis.", "content": "Calcification of selected strains of Streptococcus mutans and Streptococcus sanguis. Nine strains of cariogenic Streptococcus mutans and two strains of Streptococcus sanguis were tested for their ability to form hydroxyapatite. The cells were examined by X-ray diffraction and electron microscopy for apatite crystals after growth in a synthetic calcification medium. Each of the test isolates, except for one strain of S. sanguis, produced intracellular mineral. Two strains of S. mutans formed both intra- and extracellular crystals. There was no apparent relationship between calcifiability and serotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371107"}
{"pmid": "4371110", "title": "Stability and enzyme separation: integral representation of the solutions.", "content": "Stability and enzyme separation: integral representation of the solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371110"}
{"pmid": "4371111", "title": "Stability studies and tumor uptake of a technetium-tetracycline complex.", "content": "Stability studies and tumor uptake of a technetium-tetracycline complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371111"}
{"pmid": "4371115", "title": "Haemin and nicotinamide adenine dinucleotide requirements of Haemophilus influenzae and Haemophilus parainfluenzae.", "content": "Haemin and nicotinamide adenine dinucleotide requirements of Haemophilus influenzae and Haemophilus parainfluenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371115"}
{"pmid": "4371117", "title": "Reagin synthesis in inbred strains of rats.", "content": "Reagin synthesis in inbred strains of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371117"}
{"pmid": "4371119", "title": "The inactivation of the acyl phosphatase activity catalyzed by the sulfenic acid form of glyceraldehyde 3-phosphate dehydrogenase by dimedone and olefins.", "content": "The inactivation of the acyl phosphatase activity catalyzed by the sulfenic acid form of glyceraldehyde 3-phosphate dehydrogenase by dimedone and olefins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371119"}
{"pmid": "4371120", "title": "Vaccination against infectious bovine rhinotracheitis may hamper export trade in breeding cattle.", "content": "Vaccination against infectious bovine rhinotracheitis may hamper export trade in breeding cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371120"}
{"pmid": "4371121", "title": "The incorporation of glucose into brain glycogen and the activities of cerebral glycogen phosphorylase and synthetase: some effects of amphetamine.", "content": "The incorporation of glucose into brain glycogen and the activities of cerebral glycogen phosphorylase and synthetase: some effects of amphetamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371121"}
{"pmid": "4371123", "title": "Guanine nucleotides and thiourea as modifiers of dynein ATPase and CTPase activity.", "content": "Guanine nucleotides and thiourea as modifiers of dynein ATPase and CTPase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371123"}
{"pmid": "4371124", "title": "Combined contrast and radionuclide angiography of the liver.", "content": "Combined contrast and radionuclide angiography of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371124"}
{"pmid": "4371125", "title": "Cholinergic control by endogenous prostaglandins of cAMP accumulation under TSH stimulation in the thyroid.", "content": "Cholinergic control by endogenous prostaglandins of cAMP accumulation under TSH stimulation in the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371125"}
{"pmid": "4371126", "title": "The influence of calcium on the molecular mobility of fatty acid spin labels in phosphatidylserine and phosphatidylinositol structures.", "content": "The influence of calcium on the molecular mobility of fatty acid spin labels in phosphatidylserine and phosphatidylinositol structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371126"}
{"pmid": "4371127", "title": "The influence of enzymes on the estrogen receptors of human uterus and breast carcinoma.", "content": "The influence of enzymes on the estrogen receptors of human uterus and breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371127"}
{"pmid": "4371129", "title": "The inherited blood factors of the inhabitants of Southern Arabia.", "content": "The inherited blood factors of the inhabitants of Southern Arabia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371129"}
{"pmid": "4371130", "title": "A clinical evaluation of aspiration of cysts of the breast.", "content": "A clinical evaluation of aspiration of cysts of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371130"}
{"pmid": "4371131", "title": "A clinicopathological review of 100 cases of primary malignant tumours of the liver.", "content": "A clinicopathological review of 100 cases of primary malignant tumours of the liver. One hundred cases of primary malignant tumour of the liver coming to necropsy in the period 1900-1969 have been reviewed. The overall tumour incidence was 0.46% of all necropsies. The overall tumour incidence in hepatic cirrhosis was 12.3%, but the corresponding male and female incidences were 17.5 and 4.4% respectively. There was no significantly increased tumour incidence in haemochromatosis. An increasing incidence of primary malignant tumours of the liver has been noted since 1940 and appears to be due to a corresponding increase in incidence of hepatic cirrhosis. Hepatocellular carcinomas outnumbered cholangiocarcinomas by 8 to 1, were more common in males than females (6 to 1), and in 77% of cases occurred in cirrhotic livers. Tumours supervened as a complication of macronodular or predominantly macronodular cirrhotic patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371131"}
{"pmid": "4371132", "title": "Carcinomatous lymph nodes within breast parenchyma.", "content": "Carcinomatous lymph nodes within breast parenchyma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371132"}
{"pmid": "4371133", "title": "The interaction of phospholipase C from Staphylococcus aureus and Clostridium perfringens with cell membranes.", "content": "The interaction of phospholipase C from Staphylococcus aureus and Clostridium perfringens with cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371133"}
{"pmid": "4371139", "title": "Physiological cyclic AMP in Drosophila.", "content": "Physiological cyclic AMP in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371139"}
{"pmid": "4371138", "title": "Physiological characteristics of re-innervation of skeletal muscle in the mouse.", "content": "Physiological characteristics of re-innervation of skeletal muscle in the mouse. 1. Re-innervation of soleus was studied in the mouse after either crushing the sciatic nerve or re-implanting the nerve to soleus outside the original end-plate region.2. During the early stages of re-innervation subthreshold end-plate potentials (e.p.p.s) were recorded in muscle fibres in response to nerve stimulation. Later the e.p.p.s became large enough to evoke action potentials in muscle fibres.3. The rate of recovery of the release of acetylcholine (ACh) as estimated from the quantal content of e.p.p.s was faster when nerves re-innervated the old end-plate region after nerve crush than after re-implantation so that new neuromuscular junctions were formed.4. During re-innervation soleus fatigued more rapidly than normal during repetitive nerve stimulation. The fatigue was due to failure of neuromuscular transmission associated with an impaired release of ACh.5. During re-innervation soleus was supersensitive to ACh until nerve stimulation was capable of evoking action potentials in muscle fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371138"}
{"pmid": "4371143", "title": "Erosions of the petrous temporal bone.", "content": "Erosions of the petrous temporal bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371143"}
{"pmid": "4371148", "title": "Multiple divergent copies of endogenous C-type virogenes in mammalian cells.", "content": "Multiple divergent copies of endogenous C-type virogenes in mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371148"}
{"pmid": "4371147", "title": "Multiple control mechanisms underlie initiation of growth in animal cells.", "content": "Multiple control mechanisms underlie initiation of growth in animal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371147"}
{"pmid": "4371149", "title": "Apolipoprotein B levels and altered lipoprotein composition in diabetes.", "content": "Apolipoprotein B levels and altered lipoprotein composition in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371149"}
{"pmid": "4371150", "title": "Repair replication and photorepair of DNA in larvae of Drosophila melanogaster.", "content": "Repair replication and photorepair of DNA in larvae of Drosophila melanogaster. Repair replication of DNA has been studied in first instar larvae of Drosophila melanogaster with isopycnic centrifugation techniques. Larvae were fed BUdR, FUdR, streptomycin, penicillin, and Fungazone for two to four hours prior to exposure to UV, X-rays, MMS, or EMS. Feeding was continued for four hours in the presence of (3)HBUdR and DNA was isolated from whole larvae. Repair replication is stimulated by each of these agents. MMS is about 10 times as potent as EMS in stimulating repair synthesis. A dose of 200 ergs/mm(2) largely saturates the level of repair replication observed after UV irradiation. Repair replication rises between 0 and 80,000 R of X-rays before falling off. Semiconservative synthesis is seriously inhibited above a dose of 40,000 R of X-rays. Photorepair has been detected as a reduction in repair synthesis resulting from post-irradiation exposure to photoreactivating light. The same treatment has no detectable effect on X-ray-stimulated repair replication. Repair replication is insensitive to the presence of caffeine or hydroxyurea during the final incubation, although semiconservative synthesis is strongly inhibited by these agents. A mixture of BUdR and (3)HTdR can be used to replace (3)HBUdR in detecting repair replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371150"}
{"pmid": "4371151", "title": "Respiration for protection against cotton dust.", "content": "Respiration for protection against cotton dust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371151"}
{"pmid": "4371153", "title": "Of birds and mice and men: comments on the use of animal models and molecular hybridization in the search for human tumor viruses.", "content": "Of birds and mice and men: comments on the use of animal models and molecular hybridization in the search for human tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371153"}
{"pmid": "4371152", "title": "Respiratory activities associated with mesosomal vesicles and protoplast membranes of Staphylococcus aureus.", "content": "Respiratory activities associated with mesosomal vesicles and protoplast membranes of Staphylococcus aureus. Analysis of oxidase and dehydrogenase activities, cytochrome content of mesosomal vesicles, and protoplast membranes showed that the respiratory chain in Staphylococcus aureus is associated predominantly with the protoplast membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371152"}
{"pmid": "4371154", "title": "Impaired autoregulation of blood flow and glomerular filtration rate in the isolated dog kidney depleted of renin.", "content": "Impaired autoregulation of blood flow and glomerular filtration rate in the isolated dog kidney depleted of renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371154"}
{"pmid": "4371155", "title": "Requirement of thymus-derived theta-positive lymphocytes for rejection of DNA virus (SV 40) tumors in mice.", "content": "Requirement of thymus-derived theta-positive lymphocytes for rejection of DNA virus (SV 40) tumors in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371155"}
{"pmid": "4371157", "title": "Cortisol dynamics in the adrenal venous effluent.", "content": "Cortisol dynamics in the adrenal venous effluent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371157"}
{"pmid": "4371156", "title": "Acquisition of chick cytosol thymidine kinase activity by thymidine kinase-deficient mouse fibroblast cells after fusion with chick erythrocytes.", "content": "Acquisition of chick cytosol thymidine kinase activity by thymidine kinase-deficient mouse fibroblast cells after fusion with chick erythrocytes. Chick-mouse heterokaryons were obtained by UV-Sendai virus-induced fusion of chick erythrocytes with thymidine (dT) kinase-deficient mouse fibroblast [LM(TK(-))] cells. Autoradiographic studies demonstrated that 1 day after fusion, [(3)H]dT was incorporated into both red blood cell and LM(TK(-)) nuclei of 23% of the heterokaryons. Self-fused LM(TK(-)) cells failed to incorporate [(3)H]dT into nuclear DNA. 15 clonal lines of chick-mouse somatic cell hybrids [LM(TK(-))/CRB] were isolated from the heterokaryons by cultivating them in selective hypoxanthine-aminopterin-thymidine-glycine medium. LM(TK(-)) and chick erythrocytes exhibited little, if any, cytosol dT kinase activity. In contrast, all 15 LM(TK(-))/CRB lines contained levels of cytosol dT kinase activity comparable to that found in chick embryo cells. Disk polyacrylamide gel electrophoresis and isoelectric focusing analyses demonstrated that the LM(TK(-))/CRB cells contained chick cytosol, but not mouse cytosol dT kinase. The LM(TK(-))/CRB cells also contained mouse mitochondrial, but not chick mitochondrial dT kinase. Hence, the clonal lines were somatic cell hybrids and not LM(TK(-)) cell revertants. The experiments demonstrate that chick erythrocyte cytosol dT kinase can be activated in heterokaryons and in hybrid cells, most likely as a result of functions supplied by mouse fibroblast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371156"}
{"pmid": "4371158", "title": "The isolation and characterization of plasma membrane from cultured chicken embryo fibroblasts.", "content": "The isolation and characterization of plasma membrane from cultured chicken embryo fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371158"}
{"pmid": "4371159", "title": "The isolation of anaerobic bacteria from wound swabs.", "content": "The isolation of anaerobic bacteria from wound swabs. The isolation of anaerobic bacteria from routine wound swabs by three procedures was evaluated. Recovery of anaerobic organisms was doubled by immediate incubation of seeded plates, and the recovery could be further dramatically improved by the use of prereduced media, in conjunction with an anaerobic chamber. Recommendations for the treatment of swabs and cultures for anaerobic investigation are made.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371159"}
{"pmid": "4371160", "title": "The isolation of lung lamellar bodies.", "content": "The isolation of lung lamellar bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371160"}
{"pmid": "4371162", "title": "The isolation of outer and inner mitochondrial membranes.", "content": "The isolation of outer and inner mitochondrial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371162"}
{"pmid": "4371161", "title": "The isolation of lysosomes from brain.", "content": "The isolation of lysosomes from brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371161"}
{"pmid": "4371164", "title": "Persistent infections with herpesviruses.", "content": "Persistent infections with herpesviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371164"}
{"pmid": "4371163", "title": "The isolation of strict anaerobes: the use of an anaerobic cabinet compared with a conventional procedure.", "content": "The isolation of strict anaerobes: the use of an anaerobic cabinet compared with a conventional procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371163"}
{"pmid": "4371165", "title": "Rabbit brain phosphofructokinase. Comparison of regulatory properties with those of other phosphofructokinase isozymes.", "content": "Rabbit brain phosphofructokinase. Comparison of regulatory properties with those of other phosphofructokinase isozymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371165"}
{"pmid": "4371166", "title": "Pituitary adenomas: factors in treatment.", "content": "Pituitary adenomas: factors in treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371166"}
{"pmid": "4371168", "title": "Sensitive in vivo assay for detection of murine leukemia viruses.", "content": "Sensitive in vivo assay for detection of murine leukemia viruses. A test is reported for the in vivo detection of the replicative ability of murine leukemia viruses (MLV) in the BALB/c mouse strain. Growth in the spleen was assayed by the complement-fixation assay for MLV group-specific antigen after injection of newborn mice. Low doses of laboratory-derived and wild-type MLV from cell-culture and animal-grown sources were detected as early as 7 to 14 days postinoculation. The sensitivity of this in vivo test compared favorably with in vitro assays for MLV. In vivo detection of MLV replication was correlated with long-term oncogenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371168"}
{"pmid": "4371169", "title": "Calcitonin receptors on cultured human lymphocytes.", "content": "Calcitonin receptors on cultured human lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371169"}
{"pmid": "4371170", "title": "In vitro association of unique species of cellular 4S RNA with 35S RNA of RNA tumor viruses.", "content": "In vitro association of unique species of cellular 4S RNA with 35S RNA of RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371170"}
{"pmid": "4371171", "title": "In vitro release of corticosteroids from adrenal glands of obese-hyperglycemic mice (gene symbol ob).", "content": "In vitro release of corticosteroids from adrenal glands of obese-hyperglycemic mice (gene symbol ob).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371171"}
{"pmid": "4371172", "title": "In vitro transfer of cellular immunity against nasopharyngeal carcinoma using transfer factor from donors with Epstein-Barr virus antibody activity.", "content": "In vitro transfer of cellular immunity against nasopharyngeal carcinoma using transfer factor from donors with Epstein-Barr virus antibody activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371172"}
{"pmid": "4371173", "title": "Calcium binding to brain plasma membranes.", "content": "Calcium binding to brain plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371173"}
{"pmid": "4371174", "title": "Survival of Clostridium perfringens on chicken cooked with microwave energy.", "content": "Survival of Clostridium perfringens on chicken cooked with microwave energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371174"}
{"pmid": "4371178", "title": "Marek's disease virus and the herpesvirus of turkeys.", "content": "Marek's disease virus and the herpesvirus of turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371178"}
{"pmid": "4371179", "title": "Breakdown of intracellular NAD by streptococcal NAD--glycohydrolase EC 3.2.2.5.", "content": "Breakdown of intracellular NAD by streptococcal NAD--glycohydrolase EC 3.2.2.5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371179"}
{"pmid": "4371180", "title": "The kinetics of formation and biological activity of native and hybrid molecules of human follicle-stimulating hormone.", "content": "The kinetics of formation and biological activity of native and hybrid molecules of human follicle-stimulating hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371180"}
{"pmid": "4371181", "title": "Cytokinins: formation of the nucleoside-5'-triphosphate in tobacco and Acer cells.", "content": "Cytokinins: formation of the nucleoside-5'-triphosphate in tobacco and Acer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371181"}
{"pmid": "4371182", "title": "Basal cell adenoma of the salivary glands.", "content": "Basal cell adenoma of the salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371182"}
{"pmid": "4371183", "title": "Renal tubular localization of parathyroid hormone induced urinary cyclic adenosine 3',5'-monophosphate.", "content": "Renal tubular localization of parathyroid hormone induced urinary cyclic adenosine 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371183"}
{"pmid": "4371184", "title": "The laboratory in the diagnosis and management of viral hepatitis.", "content": "The laboratory in the diagnosis and management of viral hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371184"}
{"pmid": "4371186", "title": "Modulation of cyclic-AMP synthesis in the cat superior cervical ganglion by short term presynaptic stimulation.", "content": "Modulation of cyclic-AMP synthesis in the cat superior cervical ganglion by short term presynaptic stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371186"}
{"pmid": "4371185", "title": "Regulation of aldosterone synthesis.", "content": "Regulation of aldosterone synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371185"}
{"pmid": "4371188", "title": "Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins.", "content": "Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371188"}
{"pmid": "4371187", "title": "Regulation of muscle phosphorylase b kinase activity by inorganic phosphate and calcium ions.", "content": "Regulation of muscle phosphorylase b kinase activity by inorganic phosphate and calcium ions. The regulation of the activity of blowfly flight-muscle phosphorylase b kinase by P(i) and Ca(2+) was studied, and the actions of these effectors on the kinases from insect flight and rabbit leg muscles were compared. Preincubation of blowfly kinase with P(i) increased activity severalfold. The effect was concentration-dependent, with an apparent K(m) of about 20mm, and time-dependent, requiring at least 10min for maximal activation. Neither ATP nor cyclic AMP was needed, suggesting that a protein kinase may not be involved. Maximal activation of the insect kinase required Mg(2+) in addition to P(i). The apparent K(m) for Mg(2+) was 3mm. Rabbit leg-muscle phosphorylase b kinase was slightly inhibited, rather than stimulated, by P(i), and was strongly inhibited by K(+), Na(+) and Li(+). At physiological concentrations, Ca(2+) activated the phosphorylase b kinases from both blowfly flight and rabbit leg muscles. However, the responses to Ca(2+) of the enzymes from the two tissues were different. The mammalian kinase had virtually no activity in the absence of Ca(2+), and showed a large increase in activity over a narrow range of Ca(2+) concentrations. Flight-muscle kinase had appreciable activity in the absence of Ca(2+), and had a smaller increase over a wide range of Ca(2+) concentration. The concentrations of Ca(2+) required for half-activation were 0.1 and 1mum for the blowfly and rabbit enzymes respectively. The pH-activity profiles of the non-activated, phosphate- and Ca(2+)-activated kinase revealed considerable enhancement of activity with little, if any, increase in the ratio of activities at pH6.8 to those at 8.2. These results are discussed in relation to the mechanism coupling contraction to glycogenolysis and to the biochemical distinction between asynchronous and synchronous types of muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371187"}
{"pmid": "4371190", "title": "Enucleated neuroblastoma cells form neurites when treated with dibutyryl cyclic AMP.", "content": "Enucleated neuroblastoma cells form neurites when treated with dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371190"}
{"pmid": "4371191", "title": "Indolent mucoid carcinoma of stomach.", "content": "Indolent mucoid carcinoma of stomach. In a review of 574 cases of gastric carcinoma, 50 (8.7%) proved to be mucoid using defined microscopic criteria. Three histological types were recognized: pure signet-ring cell carcinoma (three cases); tumour of mixed pattern (41 cases); and an easily recognized, well differentiated type (six cases). This last group pursued an indolent course and had a mean survival time of nine years compared with mean survival times in the other two groups of five and 18 months respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371191"}
{"pmid": "4371192", "title": "Accelerated induction to two-kidney hypertension in rats and renin-angiotensin sensitivity.", "content": "Accelerated induction to two-kidney hypertension in rats and renin-angiotensin sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371192"}
{"pmid": "4371194", "title": "Restless legs syndrome. Sleep-electroencephalographic and neurologic findings.", "content": "Restless legs syndrome. Sleep-electroencephalographic and neurologic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371194"}
{"pmid": "4371193", "title": "Müllerian adenosarcoma of the uterus. A clinicopathologic analysis of ten cases of a distinctive type of müllerian mixed tumor.", "content": "Müllerian adenosarcoma of the uterus. A clinicopathologic analysis of ten cases of a distinctive type of müllerian mixed tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371193"}
{"pmid": "4371195", "title": "Complete nucleotide sequence of the cohesive ends of bacteriophage P2 deoxyribonucleic acid.", "content": "Complete nucleotide sequence of the cohesive ends of bacteriophage P2 deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371195"}
{"pmid": "4371196", "title": "Familial hyperlipidemias. Diagnosis and treatment.", "content": "Familial hyperlipidemias. Diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371196"}
{"pmid": "4371198", "title": "Insulin and growth hormone response to an oral glucose load in Ugandan hepatocellular carcinoma patients.", "content": "Insulin and growth hormone response to an oral glucose load in Ugandan hepatocellular carcinoma patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371198"}
{"pmid": "4371199", "title": "Insulin reversal of alloxan-diabetes induced changes in gingival collagen metabolism of the rat.", "content": "Insulin reversal of alloxan-diabetes induced changes in gingival collagen metabolism of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371199"}
{"pmid": "4371200", "title": "Alkaline isomerization of ferricytochrome C from Euglena gracilis.", "content": "Alkaline isomerization of ferricytochrome C from Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371200"}
{"pmid": "4371201", "title": "Insulinomas--problems of diagnosis and management.", "content": "Insulinomas--problems of diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371201"}
{"pmid": "4371202", "title": "Thallium-205 nuclear relaxation and kinetic studies of sodium and potassium ion-activated adenosine triphosphatase.", "content": "Thallium-205 nuclear relaxation and kinetic studies of sodium and potassium ion-activated adenosine triphosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371202"}
{"pmid": "4371203", "title": "Virologic studies of multiple sclerosis and other chronic and relapsing neurological diseases.", "content": "Virologic studies of multiple sclerosis and other chronic and relapsing neurological diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371203"}
{"pmid": "4371204", "title": "Virologic studies of progressive multifocal leukoencephalopathy.", "content": "Virologic studies of progressive multifocal leukoencephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371204"}
{"pmid": "4371205", "title": "Cytological and serological studies of a feline endogenous C-type virus.", "content": "Cytological and serological studies of a feline endogenous C-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371205"}
{"pmid": "4371206", "title": "Serological survey for antibodies to arboviruses in the human population of Portugal.", "content": "Serological survey for antibodies to arboviruses in the human population of Portugal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371206"}
{"pmid": "4371207", "title": "Development of a screening technic to monitor a Mycoplasma-free blu:(LE) Long-Evans rat colony.", "content": "Development of a screening technic to monitor a Mycoplasma-free blu:(LE) Long-Evans rat colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371207"}
{"pmid": "4371208", "title": "Development of antibodies to viral and tumor antigens before tumor induction in Syrian golden hamsters inoculated intravenously at 3 weeks of age with SV40.", "content": "Development of antibodies to viral and tumor antigens before tumor induction in Syrian golden hamsters inoculated intravenously at 3 weeks of age with SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371208"}
{"pmid": "4371209", "title": "Development of intranasal vaccination for the immunization of cattle against infectious bovine rhinotracheitis.", "content": "Development of intranasal vaccination for the immunization of cattle against infectious bovine rhinotracheitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371209"}
{"pmid": "4371211", "title": "Simultaneous stimulation test for the anterior pituitary hormones.", "content": "Simultaneous stimulation test for the anterior pituitary hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371211"}
{"pmid": "4371210", "title": "Models for metal-protein interaction: copper(II) complexes with some substituted cyclic dipeptides.", "content": "Models for metal-protein interaction: copper(II) complexes with some substituted cyclic dipeptides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371210"}
{"pmid": "4371215", "title": "Involutional (physiologic) bone loss in women and the feasibility of preventing structural failure.", "content": "Involutional (physiologic) bone loss in women and the feasibility of preventing structural failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371215"}
{"pmid": "4371216", "title": "Involvement of the adrenal gland in ovulation of the fowl.", "content": "Involvement of the adrenal gland in ovulation of the fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371216"}
{"pmid": "4371218", "title": "Lipolytic activity of adipose tissue. IV. The diacylglycerol lipase activity of human adipose tissue.", "content": "Lipolytic activity of adipose tissue. IV. The diacylglycerol lipase activity of human adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371218"}
{"pmid": "4371219", "title": "Serum lipid and lipoprotein concentrations in a Norwegian population sample.", "content": "Serum lipid and lipoprotein concentrations in a Norwegian population sample.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371219"}
{"pmid": "4371220", "title": "Serum lipoproteins and the liver, synthesis and catabolism.", "content": "Serum lipoproteins and the liver, synthesis and catabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371220"}
{"pmid": "4371221", "title": "Serum 17-alpha-hydroxyprogesterone, progesterone, estradiol, and testosterone in the diagnosis and management of congenital adrenal hyperplasia.", "content": "Serum 17-alpha-hydroxyprogesterone, progesterone, estradiol, and testosterone in the diagnosis and management of congenital adrenal hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371221"}
{"pmid": "4371222", "title": "Plasma angiotensin II activity in essential hypertension. Relation with vascular complications.", "content": "Plasma angiotensin II activity in essential hypertension. Relation with vascular complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371222"}
{"pmid": "4371223", "title": "Plasma clotting of female beagle dogs.", "content": "Plasma clotting of female beagle dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371223"}
{"pmid": "4371225", "title": "Plasma lipoproteins in patients with familial plasma lecithin: cholesterol acyltransferase (LCAT) deficiency--studies on the apolipoprotein composition of isolated fractions with identification of LP-X.", "content": "Plasma lipoproteins in patients with familial plasma lecithin: cholesterol acyltransferase (LCAT) deficiency--studies on the apolipoprotein composition of isolated fractions with identification of LP-X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371225"}
{"pmid": "4371224", "title": "Plasma free fatty acid and triglyceride transport kinetics in man.", "content": "Plasma free fatty acid and triglyceride transport kinetics in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371224"}
{"pmid": "4371226", "title": "Plasma testosterone during nocturnal sleep in normal men.", "content": "Plasma testosterone during nocturnal sleep in normal men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371226"}
{"pmid": "4371227", "title": "Plasma triglyceride production in man. Effect of noradrenaline infusion.", "content": "Plasma triglyceride production in man. Effect of noradrenaline infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371227"}
{"pmid": "4371228", "title": "Plasma ACTH levels in the human fetus and neonate as related to age and parturition.", "content": "Plasma ACTH levels in the human fetus and neonate as related to age and parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371228"}
{"pmid": "4371229", "title": "Plasma 17-OH-pregnenolone in normal subjects.", "content": "Plasma 17-OH-pregnenolone in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371229"}
{"pmid": "4371230", "title": "Pharmacokinetic function of the pulmonary circulation.", "content": "Pharmacokinetic function of the pulmonary circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371230"}
{"pmid": "4371232", "title": "Pharmacological evaluation of a new Ca++ antagonist, 8-(N,N-diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in skeletal muscles.", "content": "Pharmacological evaluation of a new Ca++ antagonist, 8-(N,N-diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in skeletal muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371232"}
{"pmid": "4371231", "title": "Pharmacologic regulation of the early steps of purine biosynthesis in Burkitt lymphoma cells and in Ehrlich ascites tumor cells.", "content": "Pharmacologic regulation of the early steps of purine biosynthesis in Burkitt lymphoma cells and in Ehrlich ascites tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371231"}
{"pmid": "4371233", "title": "Pharmacological properties of a potential tranquilising agent mesylphenacyrazine. II. Changes related to its repeated administration.", "content": "Pharmacological properties of a potential tranquilising agent mesylphenacyrazine. II. Changes related to its repeated administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371233"}
{"pmid": "4371234", "title": "Pharmacological studies with alkylsulfonyloxyalkyl substituted and chloroethyl substituted oxazaphosphorine-2-oxides. 1. Communication: relationship between chemical structure and pharmacological action.", "content": "Pharmacological studies with alkylsulfonyloxyalkyl substituted and chloroethyl substituted oxazaphosphorine-2-oxides. 1. Communication: relationship between chemical structure and pharmacological action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371234"}
{"pmid": "4371235", "title": "Pharmacology of angiotensin.", "content": "Pharmacology of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371235"}
{"pmid": "4371237", "title": "The management and evaluation of the solitary pulmonary nodule.", "content": "The management and evaluation of the solitary pulmonary nodule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371237"}
{"pmid": "4371240", "title": "Rheumatoid arthritis of the elbow: The results of synovectomy.", "content": "Rheumatoid arthritis of the elbow: The results of synovectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371240"}
{"pmid": "4371241", "title": "Chromatoid bodies in somatic cells of the planarian: observations on their behavior during mitosis.", "content": "Chromatoid bodies in somatic cells of the planarian: observations on their behavior during mitosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371241"}
{"pmid": "4371242", "title": "Enzyme activities and glycogen concentration in skeletal muscle in alcoholism. The effect of abstinence and physical conditioning.", "content": "Enzyme activities and glycogen concentration in skeletal muscle in alcoholism. The effect of abstinence and physical conditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371242"}
{"pmid": "4371243", "title": "Enzyme and ultrastructural characteristics of esophageal columnar epithelium.", "content": "Enzyme and ultrastructural characteristics of esophageal columnar epithelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371243"}
{"pmid": "4371244", "title": "Enzyme changes during ageing.", "content": "Enzyme changes during ageing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371244"}
{"pmid": "4371245", "title": "Cytomegalovirus infection in black children in Durban. A morbid anatomical study.", "content": "Cytomegalovirus infection in black children in Durban. A morbid anatomical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371245"}
{"pmid": "4371247", "title": "Parameters influencing the purification of calf uterus estrogen 'receptor' by affinity chromatography.", "content": "Parameters influencing the purification of calf uterus estrogen 'receptor' by affinity chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371247"}
{"pmid": "4371249", "title": "Asymmetries in Cu(II) impurity complexes in asparagine monohydrate crystals.", "content": "Asymmetries in Cu(II) impurity complexes in asparagine monohydrate crystals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371249"}
{"pmid": "4371248", "title": "Indomethacin potentiates PGE1 stimulated cyclic AMP accumulation in human synoviocytes.", "content": "Indomethacin potentiates PGE1 stimulated cyclic AMP accumulation in human synoviocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371248"}
{"pmid": "4371250", "title": "Dynamic bloodflow studies of space-occupying lesions in the liver.", "content": "Dynamic bloodflow studies of space-occupying lesions in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371250"}
{"pmid": "4371253", "title": "Dopamine and psychotic states: preliminary remarks.", "content": "Dopamine and psychotic states: preliminary remarks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371253"}
{"pmid": "4371252", "title": "Vitamin D-resistant rickets and parathyroid adenomas: renal transport of phosphate.", "content": "Vitamin D-resistant rickets and parathyroid adenomas: renal transport of phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371252"}
{"pmid": "4371254", "title": "Thiamine deficiency and oxalosis.", "content": "Thiamine deficiency and oxalosis. Type I hyperoxaluria results from reduced activity of alpha-ketoglutarate: glyoxylate carboligase, which is necessary for the synergistic decarboxylation of glyoxylate and alpha-ketoglutarate to alpha-hydroxy-beta-keto-adipate. Since thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might be expected to result in tissue oxalosis. However, there was no significant increase in the incidence of renal oxalosis in 15 patients with Wernicke's encephalopathy at necropsy compared with controls. It is possible that hyperoxaluria was present in these thiamine-deficient patients but at a urine concentration below that necessary for calcium oxalate deposition. It is also possible that the severity of the thiamine deficit required for hyperoxaluria exceeds that for the neuronal and cardiac manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371254"}
{"pmid": "4371256", "title": "Thermogram and mammogram.", "content": "Thermogram and mammogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371256"}
{"pmid": "4371255", "title": "Dopaminergic nervous transmission in Parkinson's disease.", "content": "Dopaminergic nervous transmission in Parkinson's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371255"}
{"pmid": "4371258", "title": "Thermoluminescent supralinear response as an optical emission effect for CaF2 Vk-centers.", "content": "Thermoluminescent supralinear response as an optical emission effect for CaF2 Vk-centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371258"}
{"pmid": "4371257", "title": "Low molecular weight nuclear RNA. The 3'-terminal sequence of the U2 RNA.", "content": "Low molecular weight nuclear RNA. The 3'-terminal sequence of the U2 RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371257"}
{"pmid": "4371259", "title": "A tumor associated antigen in human nephroblastomas.", "content": "A tumor associated antigen in human nephroblastomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371259"}
{"pmid": "4371260", "title": "Pleomorphic salivary adenoma of the lower lip: a rare site of occurrence.", "content": "Pleomorphic salivary adenoma of the lower lip: a rare site of occurrence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371260"}
{"pmid": "4371262", "title": "Jaw movements and rumen motility as criteria for measurement of deep sleep in cattle.", "content": "Jaw movements and rumen motility as criteria for measurement of deep sleep in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371262"}
{"pmid": "4371261", "title": "Chromosomal nonhistone proteins of rat hepatomas and normal rat liver.", "content": "Chromosomal nonhistone proteins of rat hepatomas and normal rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371261"}
{"pmid": "4371263", "title": "A simple direct assay for cyclic AMP in plasma and other biological samples using an improved competitive protein binding technique.", "content": "A simple direct assay for cyclic AMP in plasma and other biological samples using an improved competitive protein binding technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371263"}
{"pmid": "4371264", "title": "A simple method for density gradient zonal electrophoresis with imidazole-glycine buffer and its application to a study of cyclic AMP-binding protein.", "content": "A simple method for density gradient zonal electrophoresis with imidazole-glycine buffer and its application to a study of cyclic AMP-binding protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371264"}
{"pmid": "4371265", "title": "A simple method for routine determination of adenylate cyclase activity in intact fat cells.", "content": "A simple method for routine determination of adenylate cyclase activity in intact fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371265"}
{"pmid": "4371266", "title": "The mutagenic effect of ethylmethanesulfonate on Drosophila melanogaster sperm and spermatids.", "content": "The mutagenic effect of ethylmethanesulfonate on Drosophila melanogaster sperm and spermatids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371266"}
{"pmid": "4371268", "title": "Human cancer virus vaccines and the pursuit of the practical.", "content": "Human cancer virus vaccines and the pursuit of the practical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371268"}
{"pmid": "4371267", "title": "Human cancer and animal viral oncology.", "content": "Human cancer and animal viral oncology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371267"}
{"pmid": "4371269", "title": "Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state.", "content": "Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Human primary skin fibroblasts trisomic for chromosome 13, 18, or 21 and diploid human skin fibroblasts were induced for an antiviral response with human interferon. The cells that were trisomnic for chromosome 21 were three to seven times more sensitive to protection by human interferon than the normal diploid or trisomic 18 or 13 fibroblasts. The differential response in trisomnic 21 cells is consistent with the known assignment of the human antiviral gene to chromosome 21.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371269"}
{"pmid": "4371271", "title": "Human hemopexin. Preparation and magnetic properties.", "content": "Human hemopexin. Preparation and magnetic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371271"}
{"pmid": "4371272", "title": "Human liver nuclear transcortin. Its postulated role in glucocorticoid regulation of genetic activity.", "content": "Human liver nuclear transcortin. Its postulated role in glucocorticoid regulation of genetic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371272"}
{"pmid": "4371273", "title": "Human IMP dehydrogenase. Kinetics and regulatory properties.", "content": "Human IMP dehydrogenase. Kinetics and regulatory properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371273"}
{"pmid": "4371274", "title": "Renin-secreting juxtaglomerular-cell tumour.", "content": "Renin-secreting juxtaglomerular-cell tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371274"}
{"pmid": "4371275", "title": "Renin, angiotensin II and juxtaglomerular apparatus in liver cirrhosis.", "content": "Renin, angiotensin II and juxtaglomerular apparatus in liver cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371275"}
{"pmid": "4371276", "title": "Renin, angiotensin, and aldosterone.", "content": "Renin, angiotensin, and aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371276"}
{"pmid": "4371277", "title": "An anaerobic screw-cap culture tube.", "content": "An anaerobic screw-cap culture tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371277"}
{"pmid": "4371278", "title": "Coronavirus infection in acute lower respiratory tract disease of infants.", "content": "Coronavirus infection in acute lower respiratory tract disease of infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371278"}
{"pmid": "4371279", "title": "Absence of action potentials in frog slow muscle fibres paralysed by botulinum toxin.", "content": "Absence of action potentials in frog slow muscle fibres paralysed by botulinum toxin. 1. As shown previously, slow muscle fibres of the frog develop the ability to produce action potentials in 2 weeks after denervation.2. Normal transmission at the slow fibre neuromuscular junction gives a junction potential of 11 mV average (range 6-20 mV), caused by summation of potentials from several motor axons.3. Botulinum toxin injected intramuscularly into the iliofibularis blocks the neuromuscular junction of slow fibres in 6 days at room temperature. Single nerve stimuli give junction potentials of 0.05 mV average (range 0-1.6 mV). Contraction of slow fibres in response to tetanic stimulation is eliminated.4. No action potentials could be elicited in botulinum treated fibres, even 6(1/2) weeks after injection of toxin. This finding is discussed in relation to the possible involvement of a ;trophic' factor regulating the action potential mechanism in frog slow muscle fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371279"}
{"pmid": "4371280", "title": "Enhancement of bee venom phospholipase A2 activity by melittin, direct lytic factor from cobra venom and polymyxin B.", "content": "Enhancement of bee venom phospholipase A2 activity by melittin, direct lytic factor from cobra venom and polymyxin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371280"}
{"pmid": "4371281", "title": "Enhancement of simian virus 40 infection in simian and human cells by permissive cell extracts.", "content": "Enhancement of simian virus 40 infection in simian and human cells by permissive cell extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371281"}
{"pmid": "4371283", "title": "Equine infectious anemia.", "content": "Equine infectious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371283"}
{"pmid": "4371284", "title": "Canine lingual granular cell myoblastoma: a case report.", "content": "Canine lingual granular cell myoblastoma: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371284"}
{"pmid": "4371282", "title": "Advances in ocular therapy: noncorticosteroid anti-inflammatory agents. Fifth annual Jules Stein Lecture.", "content": "Advances in ocular therapy: noncorticosteroid anti-inflammatory agents. Fifth annual Jules Stein Lecture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371282"}
{"pmid": "4371285", "title": "Bovine lymphosarcoma (leukemia)-a synopsis.", "content": "Bovine lymphosarcoma (leukemia)-a synopsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371285"}
{"pmid": "4371287", "title": "Immune responses to virus induced experimental leukemia and to human leukemia.", "content": "Immune responses to virus induced experimental leukemia and to human leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371287"}
{"pmid": "4371286", "title": "Purine nucleotide metabolism in the cat brain after one hour of complete ischemia.", "content": "Purine nucleotide metabolism in the cat brain after one hour of complete ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371286"}
{"pmid": "4371288", "title": "Corynebacterium ulcerans mastitis in a bonnet macaque (Macaca radiata).", "content": "Corynebacterium ulcerans mastitis in a bonnet macaque (Macaca radiata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371288"}
{"pmid": "4371289", "title": "Cutaneous afferent stimulation for relief of chronic pain.", "content": "Cutaneous afferent stimulation for relief of chronic pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371289"}
{"pmid": "4371291", "title": "Cutaneous Herpesvirus hominis (type 2) infection after renal transplantation.", "content": "Cutaneous Herpesvirus hominis (type 2) infection after renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371291"}
{"pmid": "4371290", "title": "Cutaneous pseudolymphoma resulting from antigen injections.", "content": "Cutaneous pseudolymphoma resulting from antigen injections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371290"}
{"pmid": "4371292", "title": "The nephrotic syndrome in the first year of life: is a pathologic classification possible?", "content": "The nephrotic syndrome in the first year of life: is a pathologic classification possible?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371292"}
{"pmid": "4371293", "title": "On influence of aflatoxin B1 on the physical properties of the avian myeloblastosis virus BAI strain A (AMV) and on the biosynthesis of viral nucleic acids.", "content": "On influence of aflatoxin B1 on the physical properties of the avian myeloblastosis virus BAI strain A (AMV) and on the biosynthesis of viral nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371293"}
{"pmid": "4371295", "title": "Laryngeal pleomorphic adenoma.", "content": "Laryngeal pleomorphic adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371295"}
{"pmid": "4371294", "title": "Typing Herpesvirus hominis antibodies and isolates by inhibition of the indirect hemagglutination reaction.", "content": "Typing Herpesvirus hominis antibodies and isolates by inhibition of the indirect hemagglutination reaction. Inhibition of the indirect hemagglutination reaction (IHA inhibition) was compared to several other methods for type-specific identification of Herpesvirus hominis (HVH) antibodies and isolates. The method appears to have the greatest value for typing antibodies for HVH type 1 and HVH type 2 in human sera; identification of antibody type was relatively simple and results were definitive. The IHA-inhibition test permitted serological diagnosis of HVH type 2 infection in three young adults with meningoencephalitis, thus extending the mounting evidence that nervous system involvement with this virus type is not limited to neonatal infections. II/I indexes of neutralizing or IHA antibody gave an accurate indication of the presence of HVH type 2 antibody in those sera containing type 2 antibody by IHA inhibition, but they indicated the presence of HVH type 2 antibody in one-half or more of the sera shown to contain only HVH type 1 antibody by IHA inhibition. For typing HVH isolates, the IHA-inhibition test gave results identical to those obtained by direct fluorescent-antibody staining using cross-absorbed conjugates, but the IHA-inhibition test was much more cumbersome and time-consuming to perform than was direct fluorescent-antibody staining. A microneutralization technique for virus typing also gave results identical to those obtained with direct fluorescent-antibody staining and IHA inhibition. However, typing HVH isolates by plaque size or the differential effect of incubation temperature was found to be less definitive and accurate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371294"}
{"pmid": "4371296", "title": "Meningeal reactions seen with myodil myelography.", "content": "Meningeal reactions seen with myodil myelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371296"}
{"pmid": "4371298", "title": "An angiotensin converting-enzyme inhibitor to identify and treat vasoconstrictor and volume factors in hypertensive patients.", "content": "An angiotensin converting-enzyme inhibitor to identify and treat vasoconstrictor and volume factors in hypertensive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371298"}
{"pmid": "4371300", "title": "Chronic destructive polyarthritis due to pyrophosphate crystal arthritis (\"pseudogout\" syndrome).", "content": "Chronic destructive polyarthritis due to pyrophosphate crystal arthritis (\"pseudogout\" syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371300"}
{"pmid": "4371299", "title": "Ammonia formation in brain slices.", "content": "Ammonia formation in brain slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371299"}
{"pmid": "4371301", "title": "Chronic effects of botulinum toxin on neuromuscular transmission and sensitivity to acetylcholine in slow and fast skeletal muscle of the mouse.", "content": "Chronic effects of botulinum toxin on neuromuscular transmission and sensitivity to acetylcholine in slow and fast skeletal muscle of the mouse. 1. A sublethal dose of botulinum toxin (type A) was injected into the muscles of one hind limb of the mouse causing local paralysis.2. Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3. Both soleus and EDL failed to respond to nerve stimulation within 6 hr of the injection of toxin.4. In muscle fibres in which neuromuscular transmission was blocked, subthreshold end-plate potentials (e.p.p.s) were recorded. The amplitude of the e.p.p.s increased during recovery from the effects of the toxin and both muscles contracted in response to nerve stimulation after 2-3 weeks.5. For about 2 months muscles fatigued more rapidly than normal during repetitive nerve stimulation because of the low quantal content of e.p.p.s.6. Supersensitivity to ACh developed in 3-5 days and persisted after the return of neuromuscular transmission. Muscle sensitivity to ACh became normal when the rate of fatigue during nerve stimulation was normal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371301"}
{"pmid": "4371305", "title": "Subunit structure of the apoprotein of human serum low density lipoproteins.", "content": "Subunit structure of the apoprotein of human serum low density lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371305"}
{"pmid": "4371306", "title": "Meconium corpuscles in intestinal epithelium of fetal and newborn primates.", "content": "Meconium corpuscles in intestinal epithelium of fetal and newborn primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371306"}
{"pmid": "4371308", "title": "Melanocyte function: influence of cyclic adenosine monophosphate.", "content": "Melanocyte function: influence of cyclic adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371308"}
{"pmid": "4371307", "title": "Adrenocorticotropin stimulation of cyclic adenosine 3', 5'-monophosphate formation in isolated rat adrenal cells. The role of membrane sialic acid.", "content": "Adrenocorticotropin stimulation of cyclic adenosine 3', 5'-monophosphate formation in isolated rat adrenal cells. The role of membrane sialic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371307"}
{"pmid": "4371310", "title": "Immunologic evidence for horizontal transmission of MTV.", "content": "Immunologic evidence for horizontal transmission of MTV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371310"}
{"pmid": "4371309", "title": "Immunofluorescent demonstration of double-stranded RNA and virus antigen in RNA virus-infected cells.", "content": "Immunofluorescent demonstration of double-stranded RNA and virus antigen in RNA virus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371309"}
{"pmid": "4371311", "title": "Immunological destruction of herpes simplex virus I infected cells.", "content": "Immunological destruction of herpes simplex virus I infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371311"}
{"pmid": "4371312", "title": "Immunological intervention in neoplasia.", "content": "Immunological intervention in neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371312"}
{"pmid": "4371315", "title": "Immunotherapy of guinea pig cancer with BCG.", "content": "Immunotherapy of guinea pig cancer with BCG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371315"}
{"pmid": "4371313", "title": "An anomaly of the genetic regulation of the de novo pyrimidine pathway in the plant Arabidopsis.", "content": "An anomaly of the genetic regulation of the de novo pyrimidine pathway in the plant Arabidopsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371313"}
{"pmid": "4371316", "title": "Toxins and enzymes of coagulase negative staphylococci isolated from human infections.", "content": "Toxins and enzymes of coagulase negative staphylococci isolated from human infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371316"}
{"pmid": "4371317", "title": "A sensitive method for the separation and quantitation of (14C)proline and (14C)hydroxyproline from the collagen of rat uterus.", "content": "A sensitive method for the separation and quantitation of (14C)proline and (14C)hydroxyproline from the collagen of rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371317"}
{"pmid": "4371318", "title": "Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. VII. Stimulation of benzphetamine N-demethylation by lipid and detergent.", "content": "Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. VII. Stimulation of benzphetamine N-demethylation by lipid and detergent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371318"}
{"pmid": "4371320", "title": "Demonstration of collagenase activity in rat liver homogenate.", "content": "Demonstration of collagenase activity in rat liver homogenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371320"}
{"pmid": "4371321", "title": "Demonstration of low-titer anti-Pr cold agglutinins.", "content": "Demonstration of low-titer anti-Pr cold agglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371321"}
{"pmid": "4371322", "title": "Demonstration of the in vivo action of pepstatin: effects on plasma angiotensin II concentration.", "content": "Demonstration of the in vivo action of pepstatin: effects on plasma angiotensin II concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371322"}
{"pmid": "4371314", "title": "Diagnosis of salivary gland tumors.", "content": "Diagnosis of salivary gland tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371314"}
{"pmid": "4371323", "title": "Potential generation in bilayer lipid membranes in the NADH-flavin mononucleotide-ubiquinone-6-O2 system.", "content": "Potential generation in bilayer lipid membranes in the NADH-flavin mononucleotide-ubiquinone-6-O2 system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371323"}
{"pmid": "4371324", "title": "Potential X-ray contrast agents. 3. Synthesis of some derivatives of iodomethanesulphonic acid and tris-iodomethylacetic acid.", "content": "Potential X-ray contrast agents. 3. Synthesis of some derivatives of iodomethanesulphonic acid and tris-iodomethylacetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371324"}
{"pmid": "4371326", "title": "Infantile type of so-called neuronal ceroid-lipofuscinosis.", "content": "Infantile type of so-called neuronal ceroid-lipofuscinosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371326"}
{"pmid": "4371328", "title": "An ontogenic study on the effect of catecholamine receptor-stimulating agents on the turnover of noradrenaline and dopamine in the brain.", "content": "An ontogenic study on the effect of catecholamine receptor-stimulating agents on the turnover of noradrenaline and dopamine in the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371328"}
{"pmid": "4371327", "title": "Attention in the cat: electrophysiological and behavioural studies.", "content": "Attention in the cat: electrophysiological and behavioural studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371327"}
{"pmid": "4371329", "title": "Mutants of the N-3 R-factor conditionally defective in hspII modification and deoxyribonucleic acid-cytosine methylase activity.", "content": "Mutants of the N-3 R-factor conditionally defective in hspII modification and deoxyribonucleic acid-cytosine methylase activity. The N-3 drug resistance (R) factor specifies a deoxyribonucleic acid (DNA)-cytosine methylase and a DNA restriction-modification (hspII) system. We have isolated three independent mutants that are conditionally defective in their ability to modify bacteriophage lambda and to methylate DNA-cytosine residues. The ratio of 5-methylcytosine to N(6)-methyladenine in bacterial DNA and in the DNA of phages lambda and fd was determined after labeling with [methyl-(3)H]methionine at various growth temperatures. Although the ability of the wild-type N-3 factor to modify phage lambda and to methylate DNA-cytosine residues was unaffected with increasing temperature, two of the mutants exhibited a parallel loss in modification and cytosine methylation ability. The ability of the third mutant to carry out these functions was dependent on the presence or absence of an amber suppressor mutation in the host genome. These results offer further support for the notion that hspII modification is mediated by a DNA-cytosine methylase. Evidence is also presented that the modification methylase is responsible for the in vivo methylation of phage fd DNA (which is not subject to hspII restriction in vivo).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371329"}
{"pmid": "4371330", "title": "Ribonuclease H activities associated with Herpes simplex virus.", "content": "Ribonuclease H activities associated with Herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371330"}
{"pmid": "4371331", "title": "Ice nucleation induced by pseudomonas syringae.", "content": "Ice nucleation induced by pseudomonas syringae. Broth cultures of suspensions of Pseudomonas syringae isolated from decaying alder leaves (Alnus tenuifolia) were found to freeze at very warm (-1.8 to -3.8 C) temperatures. The initiation of freezing appears associated with the intact cell and not with extracellular material. Chemical treatments and physical destruction of the cell destroy activity. Bacteria must be in concentrations of approximately 10(6)/ml before freezing at warm temperatures occurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371331"}
{"pmid": "4371332", "title": "The nucleotide sequence of 5 S rRNA from the blue-green alga Anacystis nidulans.", "content": "The nucleotide sequence of 5 S rRNA from the blue-green alga Anacystis nidulans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371332"}
{"pmid": "4371333", "title": "An unusual karyotypic observation on cultured cells from an owl monkey (Aotus trivirgatus).", "content": "An unusual karyotypic observation on cultured cells from an owl monkey (Aotus trivirgatus). A cell line, established from a pathological lymph node of an owl monkey, Aotus trivirgatus s.sp. trivirgatus, was found to have two cell populations distinguished from one another by chromosome number. The normal karyotype was present in the population of cells with 54 chromosomes; the other cell population, with 55 chromosomes, possessed a normal karyotype but with one additional abnormal chromosome. The significance of this extra chromosome is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371333"}
{"pmid": "4371319", "title": "Demonstration of an enhanced alpha-adrenergic response in human adipose tissue when incubated in presence of Li+ instead of Na+.", "content": "Demonstration of an enhanced alpha-adrenergic response in human adipose tissue when incubated in presence of Li+ instead of Na+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371319"}
{"pmid": "4371336", "title": "Amino acid transport and staphylococcal membrane vesicles.", "content": "Amino acid transport and staphylococcal membrane vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371336"}
{"pmid": "4371337", "title": "Microbial penicillin acylases.", "content": "Microbial penicillin acylases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371337"}
{"pmid": "4371338", "title": "Protocatechuate 3, 4-dioxygenase. Cobalt substitution for iron.", "content": "Protocatechuate 3, 4-dioxygenase. Cobalt substitution for iron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371338"}
{"pmid": "4371339", "title": "Histochemical data on the sebaceous glands in the lips of the marmoset (Callithrix jacchus).", "content": "Histochemical data on the sebaceous glands in the lips of the marmoset (Callithrix jacchus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371339"}
{"pmid": "4371340", "title": "Histochemical localization of phosphohydrolases in testes of man and rat.", "content": "Histochemical localization of phosphohydrolases in testes of man and rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371340"}
{"pmid": "4371342", "title": "Histochemical studies of hydropic degeneration of the rat liver induced by carbon disulphide.", "content": "Histochemical studies of hydropic degeneration of the rat liver induced by carbon disulphide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371342"}
{"pmid": "4371341", "title": "Histochemical observations on the human foetal testis with reference to steroid hormone synthesis.", "content": "Histochemical observations on the human foetal testis with reference to steroid hormone synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371341"}
{"pmid": "4371346", "title": "Dissociation properties of aspartokinase I-homoserine dehydrogenase I extracted from a missense mutant of E. coli K12.", "content": "Dissociation properties of aspartokinase I-homoserine dehydrogenase I extracted from a missense mutant of E. coli K12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371346"}
{"pmid": "4371345", "title": "Dissociation of growth hormone and prolactin secretion in Parkinson's disease following chronic L-dopa therapy.", "content": "Dissociation of growth hormone and prolactin secretion in Parkinson's disease following chronic L-dopa therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371345"}
{"pmid": "4371347", "title": "Histocompatibility studies on the husband-wife pair with trophoblastic neoplasia.", "content": "Histocompatibility studies on the husband-wife pair with trophoblastic neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371347"}
{"pmid": "4371348", "title": "Glucocorticoid binding in the chicken liver cytosol.", "content": "Glucocorticoid binding in the chicken liver cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371348"}
{"pmid": "4371349", "title": "Glucocorticoids and hCG sensitivity of rat testicular Leydig cell.", "content": "Glucocorticoids and hCG sensitivity of rat testicular Leydig cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371349"}
{"pmid": "4371352", "title": "Chemodectomas.", "content": "Chemodectomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371352"}
{"pmid": "4371354", "title": "Methods for preparation of secretory granules from anterior pituitary glands.", "content": "Methods for preparation of secretory granules from anterior pituitary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371354"}
{"pmid": "4371355", "title": "Introduction of a cross-infection rate in children's wards and its application to respiratory virus infections.", "content": "Introduction of a cross-infection rate in children's wards and its application to respiratory virus infections. Statistical methods are described in detail for the calculating and comparing of cross-infection rates. In addition the use of these rates has been extended to study the influence of age and of different virus types on susceptibility to cross-infection in children's wards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371355"}
{"pmid": "4371356", "title": "Introduction to virus-caused cancer: type C virus.", "content": "Introduction to virus-caused cancer: type C virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371356"}
{"pmid": "4371357", "title": "Use of streptomycin and cyclic adenosine 5'-monophosphate in the isolation of mutants deficient in CAP protein.", "content": "Use of streptomycin and cyclic adenosine 5'-monophosphate in the isolation of mutants deficient in CAP protein. A method is described for selective isolation of mutants deficient in CAP protein necessary for the expression of catabolite-sensitive operons in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371357"}
{"pmid": "4371358", "title": "Neurofibromatosis (Recklinghausen's disease) with gastrointestinal and uterine manifestations: report of a case.", "content": "Neurofibromatosis (Recklinghausen's disease) with gastrointestinal and uterine manifestations: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371358"}
{"pmid": "4371359", "title": "Neurogenic and humoral factors controlling vascular resistance in the spontaneously hypertensive rat.", "content": "Neurogenic and humoral factors controlling vascular resistance in the spontaneously hypertensive rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371359"}
{"pmid": "4371360", "title": "Onocogenic conversion of normal cells by inactivated herpes simplex viruses.", "content": "Onocogenic conversion of normal cells by inactivated herpes simplex viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371360"}
{"pmid": "4371361", "title": "Pathogenic role of cyclic AMP in the impairment of urinary concentrating ability in acute hypercalcemia.", "content": "Pathogenic role of cyclic AMP in the impairment of urinary concentrating ability in acute hypercalcemia. A possible association between the impairment of urinary concentrating ability and an impairment of the vasopressin-dependent cyclic AMP system in hypercalcemia was investigated in rat kidneys both in vivo and in vitro. The increases of urinary osmolality and negative free water clearance and the increase of urinary cyclic AMP excretion by vasopressin injection were significantly less in the hypercalcemic rats than in the control rats. The increase of cyclic AMP concentration by vasopressin in renal medullary tissue was significantly less in the slices obtained from the hypercalcem'c rats than in those obtained from the control rats. The activation of adenylate cyclase by vasopressin was significantly less in the group with an increased concentration of calcium in media than the control group, but phosphodiesterase activity was not affected by calcium concentration in the media. These data suggest that the impaired urinary concentrating ability in hypercalcemic kidneys is due at least in part to the direct inhibitory effect of calcium on the vasopressin-dependent cyclic AMP system at the level of adenylate cyclase in renal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371361"}
{"pmid": "4371362", "title": "Pathogenicity of five Asian strains of Entamoeba histolytica in laboratory rats.", "content": "Pathogenicity of five Asian strains of Entamoeba histolytica in laboratory rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371362"}
{"pmid": "4371363", "title": "Biological properties of extracellular proteins from staphylococcus.", "content": "Biological properties of extracellular proteins from staphylococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371363"}
{"pmid": "4371364", "title": "Amniography for the detection of fetal myelomeningocele.", "content": "Amniography for the detection of fetal myelomeningocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371364"}
{"pmid": "4371365", "title": "Angiography in radiation \"hepatitis\".", "content": "Angiography in radiation \"hepatitis\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371365"}
{"pmid": "4371366", "title": "Neurohypophyseal hormones and analogues: rat pressor potency versus contractile potency on rat arterioles and arteries.", "content": "Neurohypophyseal hormones and analogues: rat pressor potency versus contractile potency on rat arterioles and arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371366"}
{"pmid": "4371367", "title": "Steroid binding in polyacrylamide gels. Quantitation at steady state conditions.", "content": "Steroid binding in polyacrylamide gels. Quantitation at steady state conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371367"}
{"pmid": "4371368", "title": "Adenoid cystic carcinoma of salivary origin. A clinicopathologic study of 242 cases.", "content": "Adenoid cystic carcinoma of salivary origin. A clinicopathologic study of 242 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371368"}
{"pmid": "4371370", "title": "Steroids, hypertension, and fluid retention in the genesis of postoperative seizures with inflammatory bowel disease in childhood.", "content": "Steroids, hypertension, and fluid retention in the genesis of postoperative seizures with inflammatory bowel disease in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371370"}
{"pmid": "4371371", "title": "Sterol compositions of echinoids (sea urchin, sand dollar and heart urchin).", "content": "Sterol compositions of echinoids (sea urchin, sand dollar and heart urchin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371371"}
{"pmid": "4371369", "title": "Steroid production by the isolated rabbit ovarian follicle. II. Effects of peptide hormones.", "content": "Steroid production by the isolated rabbit ovarian follicle. II. Effects of peptide hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371369"}
{"pmid": "4371376", "title": "Radiological examination of the stomach with a potentiated double contrast technique.", "content": "Radiological examination of the stomach with a potentiated double contrast technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371376"}
{"pmid": "4371377", "title": "Radiological follow-up examination of the mineral salt content in the various vitamin D-resistant forms of rachitis of renal origin.", "content": "Radiological follow-up examination of the mineral salt content in the various vitamin D-resistant forms of rachitis of renal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371377"}
{"pmid": "4371379", "title": "Histologically different, synchronous, bilateral carcinoma of the male breast (a case report).", "content": "Histologically different, synchronous, bilateral carcinoma of the male breast (a case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371379"}
{"pmid": "4371380", "title": "Aetiology and epidemiology of viral croup in Glasgow, 1966-72.", "content": "Aetiology and epidemiology of viral croup in Glasgow, 1966-72. A retrospective study of 258 children admitted to Ruchill Hospital, Glasgow, with croup between 1966 and 1972 indicated that the viruses most frequently associated with the syndrome were parainfluenza types 1 and 3 and influenza A. Most cases were admitted in the late autumn and winter months, with a small peak in May and June. This seasonal distribution mirrored the circulation of the main causative agents in the community, parainfluenza 1 being principally associated with the autumn cases, influenza A the winter cases and parainfluenza 3 the summer cases. Two of these ;croup associated' viruses showed regular periodicity, parainfluenza 1 occurring biennially in even years and influenza A in most years. The periodicity of parainfluenza 3 is as yet undetermined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371380"}
{"pmid": "4371382", "title": "Glycolysis in the digestive gland of healthy and parasitized Littorina saxatilis rudis (Maton) and in the daughter sporocysts of Microphallus similis (Jäg.) (Digenea: Microphallidae).", "content": "Glycolysis in the digestive gland of healthy and parasitized Littorina saxatilis rudis (Maton) and in the daughter sporocysts of Microphallus similis (Jäg.) (Digenea: Microphallidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371382"}
{"pmid": "4371381", "title": "Pathology and pathogenesis of the common diseases of the respiratory tract of cattle.", "content": "Pathology and pathogenesis of the common diseases of the respiratory tract of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371381"}
{"pmid": "4371383", "title": "Radiolysis of biochemical systems using adamantane as an isolation matrix.", "content": "Radiolysis of biochemical systems using adamantane as an isolation matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371383"}
{"pmid": "4371385", "title": "Thecoma with extensive calcification.", "content": "Thecoma with extensive calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371385"}
{"pmid": "4371384", "title": "Sarcoma and transformation-defective viruses produced with infectious DNA(s) from Rous sarcoma virus (RSV)-transformed chicken cells.", "content": "Sarcoma and transformation-defective viruses produced with infectious DNA(s) from Rous sarcoma virus (RSV)-transformed chicken cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371384"}
{"pmid": "4371386", "title": "Thymoma with systemic lupus erythematosus, red blood cell aplasia, and herpesvirus infection.", "content": "Thymoma with systemic lupus erythematosus, red blood cell aplasia, and herpesvirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371386"}
{"pmid": "4371390", "title": "Poliomyelitis in the German Federal Republic. Sporadic diseases by imported wild poliovirus.", "content": "Poliomyelitis in the German Federal Republic. Sporadic diseases by imported wild poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371390"}
{"pmid": "4371391", "title": "Carbon dioxide laser in head and neck surgery.", "content": "Carbon dioxide laser in head and neck surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371391"}
{"pmid": "4371392", "title": "Fusion of chicken erythrocytes by phospholipase C (Clostridium perfringens). The requirement for hemolytic and hydrolytic factors for fusion.", "content": "Fusion of chicken erythrocytes by phospholipase C (Clostridium perfringens). The requirement for hemolytic and hydrolytic factors for fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371392"}
{"pmid": "4371394", "title": "Action of metabolic hormones on the fine structure of rat liver cells. III. Effects of adrenalectomy and administration of cortisone.", "content": "Action of metabolic hormones on the fine structure of rat liver cells. III. Effects of adrenalectomy and administration of cortisone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371394"}
{"pmid": "4371393", "title": "Fusion of intact human erythrocytes and erythrocyte ghosts.", "content": "Fusion of intact human erythrocytes and erythrocyte ghosts. Sendai virus is able to induce the fusion of human erythrocytes. Bivalent cations or ATP are not essential for polyerythrocyte formation. High fusion indices were obtained when Sendai virus was added to cells incubated in the presence of both EDTA and iodoacetic acid. Human erythrocyte ghosts prepared by gradual hemolysis still retain the potential to undergo virus-induced fusion. Fusion of human red blood cells without the addition of viruses was obtained by incubation of erythrocytes at pH 10.5 in the presence of Ca(++) (40 mM) or by addition of phospholipase C Clostridium perfringens preparations to cells previously agglutinated or polylysine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371393"}
{"pmid": "4371395", "title": "Action of thyrotropin on phosphate incorporation into thyroid proteins in vitro.", "content": "Action of thyrotropin on phosphate incorporation into thyroid proteins in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371395"}
{"pmid": "4371396", "title": "Proton relaxation studies of diphosphopyridine coenzymes.", "content": "Proton relaxation studies of diphosphopyridine coenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371396"}
{"pmid": "4371397", "title": "Rational basis for an immunization program against the common diseases of the bovine respiratory tract.", "content": "Rational basis for an immunization program against the common diseases of the bovine respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371397"}
{"pmid": "4371399", "title": "Hormonal effects of synthetic ACTH analogues.", "content": "Hormonal effects of synthetic ACTH analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371399"}
{"pmid": "4371398", "title": "Hormonal control of the potassium level in isolated rat liver cells.", "content": "Hormonal control of the potassium level in isolated rat liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371398"}
{"pmid": "4371401", "title": "Neuronal storage disorder with chorea and curvilinear bodies.", "content": "Neuronal storage disorder with chorea and curvilinear bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371401"}
{"pmid": "4371400", "title": "Hormonal regulation of amino acid accumulation in human fetal liver explants. Effects of dibutyryl cyclic AMP, glucogon and insulin.", "content": "Hormonal regulation of amino acid accumulation in human fetal liver explants. Effects of dibutyryl cyclic AMP, glucogon and insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371400"}
{"pmid": "4371404", "title": "Hormone synthesis and release from human fetal adenohypophyses in vitro.", "content": "Hormone synthesis and release from human fetal adenohypophyses in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371404"}
{"pmid": "4371405", "title": "Components of the renin-angiotensin system in the rat during development.", "content": "Components of the renin-angiotensin system in the rat during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371405"}
{"pmid": "4371406", "title": "Actions of excitatory amino acids and their antagonism.", "content": "Actions of excitatory amino acids and their antagonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371406"}
{"pmid": "4371407", "title": "Prisons, adolescents, and the right to quality medical care: the time is now.", "content": "Prisons, adolescents, and the right to quality medical care: the time is now.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371407"}
{"pmid": "4371408", "title": "Response of isolated human ventricular myocardium to cyclic AMP and its dibutyryl derivative.", "content": "Response of isolated human ventricular myocardium to cyclic AMP and its dibutyryl derivative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371408"}
{"pmid": "4371409", "title": "Response to LH-RH in women before and after treatment with prednisone.", "content": "Response to LH-RH in women before and after treatment with prednisone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371409"}
{"pmid": "4371410", "title": "Responses of antidromically identified preoptic neurons in the rat to neurotransmitters and to estrogen.", "content": "Responses of antidromically identified preoptic neurons in the rat to neurotransmitters and to estrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371410"}
{"pmid": "4371411", "title": "Responses of guinea pig umbilical vasculature to vasoactive drugs.", "content": "Responses of guinea pig umbilical vasculature to vasoactive drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371411"}
{"pmid": "4371416", "title": "Cyclopenta(f)isoquinoline derivatives designed to bind specifically to native deoxyribonucleic acid. 3. Interaction of 6-carbamylmethyl-8-methyl-7H-cyclopenta(f)isoquinolin-3(2H)-one with deoxyribonucleic acids and polydeoxyribonucleotides.", "content": "Cyclopenta(f)isoquinoline derivatives designed to bind specifically to native deoxyribonucleic acid. 3. Interaction of 6-carbamylmethyl-8-methyl-7H-cyclopenta(f)isoquinolin-3(2H)-one with deoxyribonucleic acids and polydeoxyribonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371416"}
{"pmid": "4371417", "title": "Macrophage spreading in vitro. III. The effect of metabolic inhibitors, anesthetics and other drugs on spreading induced by subtilisin.", "content": "Macrophage spreading in vitro. III. The effect of metabolic inhibitors, anesthetics and other drugs on spreading induced by subtilisin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371417"}
{"pmid": "4371419", "title": "Hydrophobic interaction of human interferon with concanavalin A-agarose.", "content": "Hydrophobic interaction of human interferon with concanavalin A-agarose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371419"}
{"pmid": "4371421", "title": "Radioreceptor and radioimmunoassay quantitation of human growth hormone in acromegalic serum: overestimation by immunoassay and systematic differences between antisera.", "content": "Radioreceptor and radioimmunoassay quantitation of human growth hormone in acromegalic serum: overestimation by immunoassay and systematic differences between antisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371421"}
{"pmid": "4371420", "title": "Netropsin. A specific probe for A-T regions of duplex deoxyribonucleic acid.", "content": "Netropsin. A specific probe for A-T regions of duplex deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371420"}
{"pmid": "4371422", "title": "Radioreceptor assay for somatomedin A.", "content": "Radioreceptor assay for somatomedin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371422"}
{"pmid": "4371424", "title": "Editorial: Cytomegalovirus again.", "content": "Editorial: Cytomegalovirus again.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371424"}
{"pmid": "4371423", "title": "Editorial: Angiotensin inhibition.", "content": "Editorial: Angiotensin inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371423"}
{"pmid": "4371425", "title": "Editorial: Diffuse interstitial pulmonary calcification.", "content": "Editorial: Diffuse interstitial pulmonary calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371425"}
{"pmid": "4371426", "title": "Editorial: Some newer endocrine aspects of breast cancer.", "content": "Editorial: Some newer endocrine aspects of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371426"}
{"pmid": "4371427", "title": "Performance and concentration of airway washings of chickens.", "content": "Performance and concentration of airway washings of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371427"}
{"pmid": "4371428", "title": "Conformational change associated with the acylation of alpha-chymotrypsin by N-acetyl-L-phenylalanine methyl ester.", "content": "Conformational change associated with the acylation of alpha-chymotrypsin by N-acetyl-L-phenylalanine methyl ester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371428"}
{"pmid": "4371429", "title": "Conformational changes induced in Escherichia coli ribosomes by streptomycin. A spin label study.", "content": "Conformational changes induced in Escherichia coli ribosomes by streptomycin. A spin label study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371429"}
{"pmid": "4371431", "title": "Factors influencing pituitary glycogen metabolism and gonadotropic hormone release. I. Luteinizing hormone-releasing hormone.", "content": "Factors influencing pituitary glycogen metabolism and gonadotropic hormone release. I. Luteinizing hormone-releasing hormone. The way in which luteinizing hormone (LH) and follicle stimulating h ormone (FSH) are related to pituitary glycogen metabolism is investigated by measuring pituitary glycogen content and the activity of glycogen synthetase and glycogen  phosphorylase in LH-releasing hormone (LH-RH) treated rat pituitaries.  The presence of LH-RH (15 ng/flask) resulted in a significant (p less than .05) release of LH and FSH after 4 hours of incubation.  Pituitary LH content was also raised (p less than .05).  3 ng of LH-RH increased pituitary cyclic adenosine monophosphate (AMP) content by 475% in 10 minutes of incubation.  Glycogen phosphorylase was converted to its active form with 1-10 ng LH-RH per flask; this glycogenolytic activity occurred within 5 minutes (p less than .01) and was also induced by cyclic AMP in the presence of theophylline.  The forms of glycogen synthetase did not appear to be affected by LH-RH or cyclic AMP.  It is concluded that pituitary glycogen may be an energy source for release of gonadotropins via LH-RH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371431"}
{"pmid": "4371430", "title": "Conformational mobility of the pyrrolidine ring of proline in peptides and peptide hormones as manifest in carbon 13 spin-lattice relaxation times.", "content": "Conformational mobility of the pyrrolidine ring of proline in peptides and peptide hormones as manifest in carbon 13 spin-lattice relaxation times.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371430"}
{"pmid": "4371432", "title": "Factors influencing pituitary glycogen metabolism and gonadotropic hormone release. II. A role of prostaglandins.", "content": "Factors influencing pituitary glycogen metabolism and gonadotropic hormone release. II. A role of prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371432"}
{"pmid": "4371433", "title": "Osteosclerotic myeloma with peripheral neuropathy.", "content": "Osteosclerotic myeloma with peripheral neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371433"}
{"pmid": "4371434", "title": "Adenosine 3',5'-cyclic monophosphate-deficient mutants of Vibrio cholerae.", "content": "Adenosine 3',5'-cyclic monophosphate-deficient mutants of Vibrio cholerae. Two adenosine 3',5'-cyclic monophosphate (AMP)-deficient mutants of Vibrio cholerae (biotype El Tor) were successfully isolated by nitrosoguanidine treatment followed by pencillin screening for pleiotropic sugar-negative clones. Exogenous cyclic AMP is required for the fermentation of sucrose, trehalose, fructose, maltose, and mannose but not of glucose, as well as for the formation of normal flagella and specific somatic antigens. A striking characteristic of the mutants is their growth behavior at higher temperatures. They cannot grow on TCBS selective plates at 37 C or higher unless they are provided with a supply of exogenous cyclic AMP, although they are capable of producing colonies on the same medium, even without cyclic AMP, at temperatures lower than 30 C. Since the mutants are converted to spheroplasts, spindle forms, and spiral filaments in cyclic AMP-free media at 37 C, and this phenomenon is stopped by the addition of cyclic AMP or a combination of 20% sucrose and 0.2% magnesium chloride, it is assumed that cyclic AMP is essential for the synthesis of the cell wall of V. cholerae at higher temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371434"}
{"pmid": "4371435", "title": "Adenosine 3':5'-monophosphate-dependent protein kinase-catalyzed phosphorylation reaction and its relationship to calcium transport in cardiac sarcoplasmic reticulum.", "content": "Adenosine 3':5'-monophosphate-dependent protein kinase-catalyzed phosphorylation reaction and its relationship to calcium transport in cardiac sarcoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371435"}
{"pmid": "4371436", "title": "Adenosine 5'-triphosphate release and membrane collapse in glycerol-requiring mutants of Bacillus subtilis.", "content": "Adenosine 5'-triphosphate release and membrane collapse in glycerol-requiring mutants of Bacillus subtilis. Glycerol-requiring mutants of Bacillus subtilis could not sporulate in nutrient sporulation medium even when additional glycerol was added from the beginning of growth. Sporulation could be partially restored either by the frequent addition of small amounts of glycerol during the developmental period or by the single addition of both 10 mM glycerol and 10 mM malate. But sporulation could be completely restored by the addition of 50 mM glycerol-phosphate from the beginning. At the end of growth of the glycerol mutants in nutrient sporulation medium, the cell membrane collapsed and separated from the cell wall, and much of the cellular adenosine 5'-triphosphate was released into the medium. These observations were made in two glycerol mutants, one derived from strain 168 containing glycerol-teichoic acid in the cell wall and the other derived from strain W23 containing ribitol-teichoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371436"}
{"pmid": "4371439", "title": "Glycosyl glycerides.", "content": "Glycosyl glycerides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371439"}
{"pmid": "4371440", "title": "Mannosyltransferase activity in calf pancreas microsomes. Formation from guanosine diphosphate-D-(14C)mannose of a 14C-labeled mannolipid with properties of dolichyl mannopyranosyl phosphate.", "content": "Mannosyltransferase activity in calf pancreas microsomes. Formation from guanosine diphosphate-D-(14C)mannose of a 14C-labeled mannolipid with properties of dolichyl mannopyranosyl phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371440"}
{"pmid": "4371442", "title": "Hypnotic suggestions for learning during stage I REM sleep.", "content": "Hypnotic suggestions for learning during stage I REM sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371442"}
{"pmid": "4371441", "title": "A protein-bound form of porcine renal renin.", "content": "A protein-bound form of porcine renal renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371441"}
{"pmid": "4371444", "title": "Pronounced antiviral activity of human interferon on bovine and porcine cells.", "content": "Pronounced antiviral activity of human interferon on bovine and porcine cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371444"}
{"pmid": "4371443", "title": "Enzootic Brucella canis--an occult disease in a research canine colony.", "content": "Enzootic Brucella canis--an occult disease in a research canine colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371443"}
{"pmid": "4371445", "title": "An \"outbreak\" of juvenile diabetes mellitus: consideration of a viral etiology.", "content": "An \"outbreak\" of juvenile diabetes mellitus: consideration of a viral etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371445"}
{"pmid": "4371447", "title": "The oxidation state of copper in resting tyrosinase.", "content": "The oxidation state of copper in resting tyrosinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371447"}
{"pmid": "4371448", "title": "Hydroxylysine glycosides in the collagen of normal and scarred rabbit corneas.", "content": "Hydroxylysine glycosides in the collagen of normal and scarred rabbit corneas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371448"}
{"pmid": "4371449", "title": "Sleep deprivation in cattle.", "content": "Sleep deprivation in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371449"}
{"pmid": "4371446", "title": "Improved methods for the study of drug effects on purine metabolism and their application to nebularine and 7-deazanebularine.", "content": "Improved methods for the study of drug effects on purine metabolism and their application to nebularine and 7-deazanebularine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371446"}
{"pmid": "4371450", "title": "Sleep in hypnosis: a pilot EEG study.", "content": "Sleep in hypnosis: a pilot EEG study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371450"}
{"pmid": "4371454", "title": "Idiopathic sexual precocity in a boy with growth hormone, prolactin and thyrotropin deficiencies.", "content": "Idiopathic sexual precocity in a boy with growth hormone, prolactin and thyrotropin deficiencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371454"}
{"pmid": "4371455", "title": "The pathogenesis of hexachlorophene neuropathy: in vivo and in vitro studies.", "content": "The pathogenesis of hexachlorophene neuropathy: in vivo and in vitro studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371455"}
{"pmid": "4371457", "title": "Independence of cholesterol and fatty acid biosynthesis from cyclic adenosine monophosphate concentration in the perfused rat liver.", "content": "Independence of cholesterol and fatty acid biosynthesis from cyclic adenosine monophosphate concentration in the perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371457"}
{"pmid": "4371456", "title": "C-type viral particles in a urinary bladder neoplasm induced by Schistosoma haematobium.", "content": "C-type viral particles in a urinary bladder neoplasm induced by Schistosoma haematobium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371456"}
{"pmid": "4371458", "title": "Independent dibutyryl cyclic adenosine monophosphate stimulation of human chorionic gonadotropin and estrogen secretion by malignant trophoblast cells in vitro.", "content": "Independent dibutyryl cyclic adenosine monophosphate stimulation of human chorionic gonadotropin and estrogen secretion by malignant trophoblast cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371458"}
{"pmid": "4371459", "title": "Subependymal veins and ventricular tumors.", "content": "Subependymal veins and ventricular tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371459"}
{"pmid": "4371460", "title": "Polypeptide composition of urea- and heat-resistant mutants of poliovirus types 1 and 2.", "content": "Polypeptide composition of urea- and heat-resistant mutants of poliovirus types 1 and 2. Five urea-resistant and two heat-resistant mutants of poliovirus types 1 and 2 were isolated and their structural and nonstructural polypeptides compared to those of their wild-type, parental strains in an attempt to correlate mutant phenotypes with alterations in specific capsid polypeptides. Four of the seven mutants were found to contain polypeptides which differed in molecular weight from their respective parental viruses. However, resistance of virions to heat- or urea-inactivation could not be attributed to changes in particular capsid polypeptides because alterations were detected in all but one of the capsid components. For two of the urea-resistant mutants and one heat-resistant mutant, no differences were found in the molecular weights of the capsid and noncapsid polypeptides. These results, and the fact that at least 12 selective treatments were required to obtain stable mutants, indicate that: (i) such phenotypes probably can be expressed by mutations affecting one or more of the larger capsid polypeptides, and (ii) such phenotypes reflect multiple mutational steps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371460"}
{"pmid": "4371461", "title": "Polypeptides of Moloney sarcoma-leukemia virions: their resolution and incorporation into extracellular virions.", "content": "Polypeptides of Moloney sarcoma-leukemia virions: their resolution and incorporation into extracellular virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371461"}
{"pmid": "4371462", "title": "The peribrachial region of cat. II. Distribution of acetylthiocholinesterase and monoaminoxidase, with special reference to the locus coeruleus.", "content": "The peribrachial region of cat. II. Distribution of acetylthiocholinesterase and monoaminoxidase, with special reference to the locus coeruleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371462"}
{"pmid": "4371465", "title": "Phosphate metabolism in blue-green algae. I. Fine structure of the \"polyphosphate overplus\" phenomenon in Plectonema boryanum.", "content": "Phosphate metabolism in blue-green algae. I. Fine structure of the \"polyphosphate overplus\" phenomenon in Plectonema boryanum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371465"}
{"pmid": "4371468", "title": "Phospholipid exchange between membranes. Purification of bovine brain proteins that preferentially catalyze the transfer of phosphatidylinositol.", "content": "Phospholipid exchange between membranes. Purification of bovine brain proteins that preferentially catalyze the transfer of phosphatidylinositol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371468"}
{"pmid": "4371470", "title": "Phosphorylation of proteins of ribosomes and nucleolar preribosomal particles in vivo in Novikoff hepatoma ascites cells.", "content": "Phosphorylation of proteins of ribosomes and nucleolar preribosomal particles in vivo in Novikoff hepatoma ascites cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371470"}
{"pmid": "4371471", "title": "Ectopic fetal adrenal cortex in the lung of a newborn.", "content": "Ectopic fetal adrenal cortex in the lung of a newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371471"}
{"pmid": "4371473", "title": "A rapid, simple and reliable method for the screening of potential antiviral compounds in vitro.", "content": "A rapid, simple and reliable method for the screening of potential antiviral compounds in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371473"}
{"pmid": "4371472", "title": "A rapid micromethod for the determination of nitrogen and phosphate in biological material.", "content": "A rapid micromethod for the determination of nitrogen and phosphate in biological material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371472"}
{"pmid": "4371475", "title": "Cytoplasmic alterations of hepatocytes in rainbow trout (Salmo gairdneri) induced by cyclopropenoid fatty acids.", "content": "Cytoplasmic alterations of hepatocytes in rainbow trout (Salmo gairdneri) induced by cyclopropenoid fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371475"}
{"pmid": "4371476", "title": "The preparation and characterisation of a water-soluble coenzymically active dextran-NAD+.", "content": "The preparation and characterisation of a water-soluble coenzymically active dextran-NAD+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371476"}
{"pmid": "4371477", "title": "The presence of bound cyanide in the naturally inactivated form of nitrate reductase of Chlorella vulgaris.", "content": "The presence of bound cyanide in the naturally inactivated form of nitrate reductase of Chlorella vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371477"}
{"pmid": "4371478", "title": "The presence of 4-selenouridine in Escherichia coli tRNA.", "content": "The presence of 4-selenouridine in Escherichia coli tRNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371478"}
{"pmid": "4371479", "title": "Derepression of nitrogenase in Azotobacter.", "content": "Derepression of nitrogenase in Azotobacter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371479"}
{"pmid": "4371480", "title": "The process of establishing a collaborative program between a mental health center and a public health nursing division: a case study.", "content": "The process of establishing a collaborative program between a mental health center and a public health nursing division: a case study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371480"}
{"pmid": "4371474", "title": "Incipient pulmonary emphysema. II. Genetics and biochemistry.", "content": "Incipient pulmonary emphysema. II. Genetics and biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371474"}
{"pmid": "4371481", "title": "The properties of water in biological systems.", "content": "The properties of water in biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371481"}
{"pmid": "4371483", "title": "The purine DNA base cation and anion radicals: an e.s.r. study.", "content": "The purine DNA base cation and anion radicals: an e.s.r. study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371483"}
{"pmid": "4371484", "title": "The pyrophosphate exchange reaction of histidyl-tRNA synthetase from Salmonella typhimurium: reaction parameters and inhibition by transfer ribonucleic acid.", "content": "The pyrophosphate exchange reaction of histidyl-tRNA synthetase from Salmonella typhimurium: reaction parameters and inhibition by transfer ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371484"}
{"pmid": "4371482", "title": "Lipoprotein-polyanion-metal interactions.", "content": "Lipoprotein-polyanion-metal interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371482"}
{"pmid": "4371485", "title": "Water balance and kidney function in some rodents native to Australia.", "content": "Water balance and kidney function in some rodents native to Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371485"}
{"pmid": "4371486", "title": "Newer insights into the role and modifications of olfaction in man through clinical studies.", "content": "Newer insights into the role and modifications of olfaction in man through clinical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371486"}
{"pmid": "4371487", "title": "165Er: an \"ideal\" radionuclide for imaging with pressurized multiwire proportional gamma cameras.", "content": "165Er: an \"ideal\" radionuclide for imaging with pressurized multiwire proportional gamma cameras.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371487"}
{"pmid": "4371488", "title": "Interaction between adrenergic and cholinergic systems: presynaptic inhibitory effect of noradrenaline on acetylcholine release.", "content": "Interaction between adrenergic and cholinergic systems: presynaptic inhibitory effect of noradrenaline on acetylcholine release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371488"}
{"pmid": "4371489", "title": "Interaction of estradiol and ACTH in the regulation of adrenal corticosterone production in the rat.", "content": "Interaction of estradiol and ACTH in the regulation of adrenal corticosterone production in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371489"}
{"pmid": "4371490", "title": "Interaction of staphylococcal protein A with virus-IgG complexes.", "content": "Interaction of staphylococcal protein A with virus-IgG complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371490"}
{"pmid": "4371492", "title": "Accuracy of radionuclide cerebral angiograms in the detection of cerebral arteriovenous malformations.", "content": "Accuracy of radionuclide cerebral angiograms in the detection of cerebral arteriovenous malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371492"}
{"pmid": "4371493", "title": "The radiological diagnosis of congenital multicystic kidney 'Radiological Triad'.", "content": "The radiological diagnosis of congenital multicystic kidney 'Radiological Triad'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371493"}
{"pmid": "4371496", "title": "A viral inhibitory substance in culture filtrates of Proteus mirabilis. 1. Inhibition of Sindbis virus plaque formation without a parallel antiviral action in fluid medium.", "content": "A viral inhibitory substance in culture filtrates of Proteus mirabilis. 1. Inhibition of Sindbis virus plaque formation without a parallel antiviral action in fluid medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371496"}
{"pmid": "4371497", "title": "Lateral phase separations in binary lipid mixtures: correlation between spin label and freeze-fracture electron microscopic studies.", "content": "Lateral phase separations in binary lipid mixtures: correlation between spin label and freeze-fracture electron microscopic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371497"}
{"pmid": "4371498", "title": "Programming of events in Epstein-Barr virus-activated cells induced by 5-iododeoxyuridine.", "content": "Programming of events in Epstein-Barr virus-activated cells induced by 5-iododeoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371498"}
{"pmid": "4371500", "title": "Membrane proteins of MSV-MLV: their role in virion-virion interactions in vitro.", "content": "Membrane proteins of MSV-MLV: their role in virion-virion interactions in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371500"}
{"pmid": "4371499", "title": "Membrane fusion. Transfer of phospholipid molecules between phospholipid bilayer membranes.", "content": "Membrane fusion. Transfer of phospholipid molecules between phospholipid bilayer membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371499"}
{"pmid": "4371506", "title": "Separation of the two non-identical subunits of lombricine kinase from Lumbricus terrestris muscle by chromatography on sepharose-mercurial. Isolation of the tryptic peptide containing its essential thiol group.", "content": "Separation of the two non-identical subunits of lombricine kinase from Lumbricus terrestris muscle by chromatography on sepharose-mercurial. Isolation of the tryptic peptide containing its essential thiol group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371506"}
{"pmid": "4371507", "title": "Alterations of murine immunologic responses after silica dust inhalation.", "content": "Alterations of murine immunologic responses after silica dust inhalation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371507"}
{"pmid": "4371508", "title": "Alterations of surface properties of chick embryo fibroblasts infected with four Rous sarcoma viruses producing distinctive cell transformation.", "content": "Alterations of surface properties of chick embryo fibroblasts infected with four Rous sarcoma viruses producing distinctive cell transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371508"}
{"pmid": "4371509", "title": "Tuberculin testing in Macaca species: evaluation of two tuberculin diluents.", "content": "Tuberculin testing in Macaca species: evaluation of two tuberculin diluents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371509"}
{"pmid": "4371510", "title": "Disordered calcium metabolism during anticonvulsant treatment.", "content": "Disordered calcium metabolism during anticonvulsant treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371510"}
{"pmid": "4371511", "title": "The reaction of alkylating agents with cyclic 3',5'-nucleotide phosphodiesterase.", "content": "The reaction of alkylating agents with cyclic 3',5'-nucleotide phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371511"}
{"pmid": "4371512", "title": "Pancreatic islet cell carcinoma metastatic to the eyes.", "content": "Pancreatic islet cell carcinoma metastatic to the eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371512"}
{"pmid": "4371513", "title": "Indirect hemagglutinating antibody response to Herpesvirus hominis types 1 and 2 in immunized laboratory animals and in natural infections of man.", "content": "Indirect hemagglutinating antibody response to Herpesvirus hominis types 1 and 2 in immunized laboratory animals and in natural infections of man. Indirect hemagglutinating (IHA) antibody responses to Herpesvirus hominis types 1 and 2 (HVH-1 and HVH-2) were compared to complement-fixing and neutralizing antibody responses in immunized laboratory animals (rabbits, guinea pigs, and hamsters) and in natural infections of man. With the immunized animals, type specificity was seen only in the IHA test and only with antisera produced in hamsters and in the rabbits immunized with HVH-2. In human nongenital infections (considered to be caused predominately by HVH-1), IHA and neutralizing antibodies developed at about the same rate and reached approximately the same levels for HVH-1 and HVH-2. IHA titers tended to be higher than neutralizing antibody titers for both virus types. In genital infections (considered to be caused predominately by HVH-2), there was a rapid IHA antibody response to HVH-2, and the early HVH-2 antibody demonstrable by IHA, but not by neutralization tests, was found to be immunoglobulin M in nature. In genital infections, IHA titers for HVH-2 were markedly higher than neutralization titers, but there was no pronounced difference in neutralizing the IHA antibody titers for HVH-1. Several patients with genital infections fialed to develop IHA antibody for HVH-1. The IHA test possessed no greater sensitivity than did complement fixation or neutralization tests for serodiagnosis of HVH infections. Despite the fact that a number of patients with genital infections produced IHA antibody only for HVH-2, the test was no more effective than the neutralization test in providing a type-specific serodiagnosis of infection, due largely to the fact that the rapid IHA antibody response to HVH-2 prevented demonstration of a further, significant antibody titer increase in a number of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371513"}
{"pmid": "4371514", "title": "Altered amphibian cell morphology following treatment with polyene antibiotic and a mammalian RNA virus.", "content": "Altered amphibian cell morphology following treatment with polyene antibiotic and a mammalian RNA virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371514"}
{"pmid": "4371515", "title": "Altered protein metabolism in infection by the late tsB11 mutant of simian virus 40.", "content": "Altered protein metabolism in infection by the late tsB11 mutant of simian virus 40. The DNA of the temperature-sensitive mutant tsB11 is replicated at the same rate as the DNA of wild-type virus in infection at the restrictive temperature. The progeny mutant DNA cannot be distinguished from wild-type DNA by gel electrophoresis and is assembled into a nucleoprotein complex with the same velocity sedimentation characteristics as the wild-type complex. Analysis of in vivo protein synthesis by sodium dodecyl sulfate polyacrylamide gel electrophoresis and immunoprecipitation techniques demonstrated that the capsid components VP1, VP2, and VP3 of the mutant and wild-type virus are synthesized at a similar rate, but VP1 fails to accumulate within cells infected by tsB11. Furthermore, VP1 is located predominantly in the cytoplasmic rather than in the nuclear fraction of extracts from cells infected by the mutant. Immunofluorescent studies localized virion antigen within the nucleolus as well as the cytoplasm. The altered intracellular distribution and stability of VP1 suggest that it may be the mutant protein of tsB11. The synthesis of a 72,000 dalton protein is consistently induced in significant quantity in cells infected by tsB11 at the restrictive temperature. A protein of the same apparent molecular weight is present in smaller quantities in uninfected cells and is only slightly increased in quantity in cells infected by wild-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371515"}
{"pmid": "4371516", "title": "The regulation of cyclic guanosine monophosphate in rat cerebellum: possible involvement of putative amino acid neurotransmitters.", "content": "The regulation of cyclic guanosine monophosphate in rat cerebellum: possible involvement of putative amino acid neurotransmitters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371516"}
{"pmid": "4371517", "title": "Age-related changes in vascular responsiveness to cyclic nucleotides and contractile agonists.", "content": "Age-related changes in vascular responsiveness to cyclic nucleotides and contractile agonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371517"}
{"pmid": "4371518", "title": "The relationship between plasma and tissue lipids in human atherosclerosis.", "content": "The relationship between plasma and tissue lipids in human atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371518"}
{"pmid": "4371519", "title": "The relationship of total dust, free silica, and trace metal concentrations to the occupational respiratory disease of bituminous coal miners.", "content": "The relationship of total dust, free silica, and trace metal concentrations to the occupational respiratory disease of bituminous coal miners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371519"}
{"pmid": "4371520", "title": "Low renin, \"normal\" aldosterone and hypertension: circadian rhythm of renin, aldosterone, cortisol and growth hormone.", "content": "Low renin, \"normal\" aldosterone and hypertension: circadian rhythm of renin, aldosterone, cortisol and growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371520"}
{"pmid": "4371521", "title": "Apparent correlation between adenosine 3':5' cyclic monophosphate levels and malignancy in somatic cell hybrids.", "content": "Apparent correlation between adenosine 3':5' cyclic monophosphate levels and malignancy in somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371521"}
{"pmid": "4371523", "title": "The reovirus murine models.", "content": "The reovirus murine models.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371523"}
{"pmid": "4371526", "title": "Fluorescent antibody study of a new bovine herpesvirus (strain DN-599).", "content": "Fluorescent antibody study of a new bovine herpesvirus (strain DN-599).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371526"}
{"pmid": "4371524", "title": "The replication of papovavirus DNA.", "content": "The replication of papovavirus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371524"}
{"pmid": "4371525", "title": "The requirement for lipid fluidity in the formation and structure of lipoproteins: thermotropic analysis of apolipoprotein-alanine binding to dimyristoyl phosphatidylcholine.", "content": "The requirement for lipid fluidity in the formation and structure of lipoproteins: thermotropic analysis of apolipoprotein-alanine binding to dimyristoyl phosphatidylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371525"}
{"pmid": "4371527", "title": "Cigarette smoking and cholesterol atherosclerosis of rabbits.", "content": "Cigarette smoking and cholesterol atherosclerosis of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371527"}
{"pmid": "4371528", "title": "Interferon inducers in therapy of infection with encephalomyocarditis virus in mice. I. Effect of single doses of polyriboinosinic-polyribocytidylic acid and tilorone hydrochloride on viral pathogenesis.", "content": "Interferon inducers in therapy of infection with encephalomyocarditis virus in mice. I. Effect of single doses of polyriboinosinic-polyribocytidylic acid and tilorone hydrochloride on viral pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371528"}
{"pmid": "4371529", "title": "Interferon inducers in therapy of infection with encephalomyocarditis virus in mice. II. Effect of multiple doses of polyriboinosinic-polyribocytidylic acid on viral pathogenesis.", "content": "Interferon inducers in therapy of infection with encephalomyocarditis virus in mice. II. Effect of multiple doses of polyriboinosinic-polyribocytidylic acid on viral pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371529"}
{"pmid": "4371530", "title": "Interferon-mediated increased lysis of L-cells by vesicular stomatitis virus.", "content": "Interferon-mediated increased lysis of L-cells by vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371530"}
{"pmid": "4371531", "title": "Allergy involving the cranial nerves.", "content": "Allergy involving the cranial nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371531"}
{"pmid": "4371532", "title": "Synergy of 9-beta-D-arabinofuranosyladenine and human interferon against Herpes simplex virus, type 1.", "content": "Synergy of 9-beta-D-arabinofuranosyladenine and human interferon against Herpes simplex virus, type 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371532"}
{"pmid": "4371535", "title": "Distribution and persistence of avian encephalomyelitis viral antigens in internal organs of naturally infected chickens.", "content": "Distribution and persistence of avian encephalomyelitis viral antigens in internal organs of naturally infected chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371535"}
{"pmid": "4371534", "title": "Arterial cannulation in awake restrained monkeys.", "content": "Arterial cannulation in awake restrained monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371534"}
{"pmid": "4371536", "title": "Distribution of calcium and magnesium in rat kidney homogenate fractions accompanying magnesium deficiency induced nephrocalcinosis.", "content": "Distribution of calcium and magnesium in rat kidney homogenate fractions accompanying magnesium deficiency induced nephrocalcinosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371536"}
{"pmid": "4371537", "title": "Distribution of glutamate sensitivity on insect muscle fibres.", "content": "Distribution of glutamate sensitivity on insect muscle fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371537"}
{"pmid": "4371538", "title": "Distribution of sterols in the fungi. I. Fungal spores.", "content": "Distribution of sterols in the fungi. I. Fungal spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371538"}
{"pmid": "4371539", "title": "Distribution of WR-2721 in normal and malignant tissues of mice and rats bearing solid tumors: dependence on tumor type, drug dose and species.", "content": "Distribution of WR-2721 in normal and malignant tissues of mice and rats bearing solid tumors: dependence on tumor type, drug dose and species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371539"}
{"pmid": "4371541", "title": "Experimental herpes virus arthritis. Factors in chronicity.", "content": "Experimental herpes virus arthritis. Factors in chronicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371541"}
{"pmid": "4371540", "title": "Centrifugation.", "content": "Centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371540"}
{"pmid": "4371542", "title": "Experimental investigations on the influence upon the chemical carcinogenesis. 1st Communication: Studies with ethylnitroso-urea.", "content": "Experimental investigations on the influence upon the chemical carcinogenesis. 1st Communication: Studies with ethylnitroso-urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371542"}
{"pmid": "4371543", "title": "Experimental Zieria arborescens (stinkwood) poisoning in rabbits.", "content": "Experimental Zieria arborescens (stinkwood) poisoning in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371543"}
{"pmid": "4371546", "title": "Abnormal accumulation of sialoglycoproteins in a case of late infantile amaurotic idiocy.", "content": "Abnormal accumulation of sialoglycoproteins in a case of late infantile amaurotic idiocy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371546"}
{"pmid": "4371544", "title": "Description by quasi elastic laser light scattering of a biological preparation: sarcoplasmic reticulum vesicles.", "content": "Description by quasi elastic laser light scattering of a biological preparation: sarcoplasmic reticulum vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371544"}
{"pmid": "4371547", "title": "Abnormal brain scan in Paget's disease of bone-confusion with subdural hematoma.", "content": "Abnormal brain scan in Paget's disease of bone-confusion with subdural hematoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371547"}
{"pmid": "4371548", "title": "Determination of \"free\" testosterone in plasma by GLC-63Ni ECD.", "content": "Determination of \"free\" testosterone in plasma by GLC-63Ni ECD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371548"}
{"pmid": "4371550", "title": "Oncornavirus directed tumor cell surface antigens detectable by humoral and cellular immunity.", "content": "Oncornavirus directed tumor cell surface antigens detectable by humoral and cellular immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371550"}
{"pmid": "4371549", "title": "Determination of the degree of in vivo tRNA aminoacylation in yeast cells.", "content": "Determination of the degree of in vivo tRNA aminoacylation in yeast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371549"}
{"pmid": "4371552", "title": "Oestrogen receptors and antagonism of steroid hormone action.", "content": "Oestrogen receptors and antagonism of steroid hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371552"}
{"pmid": "4371554", "title": "Gastrointestinal fibroma. A clinicopathological study.", "content": "Gastrointestinal fibroma. A clinicopathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371554"}
{"pmid": "4371555", "title": "Control of phospholipid peroxidation and enzyme activity losses in mitochondria by antioxidants.", "content": "Control of phospholipid peroxidation and enzyme activity losses in mitochondria by antioxidants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371555"}
{"pmid": "4371556", "title": "Control of uterine blood flow in pregnancy.", "content": "Control of uterine blood flow in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371556"}
{"pmid": "4371557", "title": "The role of calcium in insulin action. II. Effects of insulin and procaine hydrochloride on lipolysis.", "content": "The role of calcium in insulin action. II. Effects of insulin and procaine hydrochloride on lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371557"}
{"pmid": "4371558", "title": "The role of carboxyl, imidazole, and amino groups in inorganic pyrophosphatase of baker's yeast.", "content": "The role of carboxyl, imidazole, and amino groups in inorganic pyrophosphatase of baker's yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371558"}
{"pmid": "4371559", "title": "The role of choline in maintaining the fine structure of nerve terminals in the superior cervical ganglion of cat.", "content": "The role of choline in maintaining the fine structure of nerve terminals in the superior cervical ganglion of cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371559"}
{"pmid": "4371560", "title": "The role of cyclic nucleotides in the development and function of rat mammary tissue.", "content": "The role of cyclic nucleotides in the development and function of rat mammary tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371560"}
{"pmid": "4371562", "title": "The role of mineralocorticoids in the pathogenesis of hypokalemic periodic paralysis.", "content": "The role of mineralocorticoids in the pathogenesis of hypokalemic periodic paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371562"}
{"pmid": "4371561", "title": "The role of cyclic AMP in neoplastic cell growth and regression. II. Growth arrest and glucose-6-phosphate dehydrogenase isozyme shift by dibutyryl cyclic AMP.", "content": "The role of cyclic AMP in neoplastic cell growth and regression. II. Growth arrest and glucose-6-phosphate dehydrogenase isozyme shift by dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371561"}
{"pmid": "4371564", "title": "The role of the polyol pathway in methaemoglobin reduction in human red cells.", "content": "The role of the polyol pathway in methaemoglobin reduction in human red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371564"}
{"pmid": "4371563", "title": "The role of platelet membrane phospholipids in the platelet release reaction.", "content": "The role of platelet membrane phospholipids in the platelet release reaction. The structure and function of the platelet surface was probed by phospholipase C (Clostridium perfringens) which hydrolyzes membrane phospholipids, particularly phosphatidylcholine. Platelet phospholipids were susceptible to phospholipase C, and extent of hydrolysis was dependent on concentration of phospholipase C and Ca(++). Phospholipase C (0.15 U/ml) with Ca(++) (0.55 mM) hydrolyzed 15.6% phospholipids during 5 min. Phospholipase C released platelet serotonin (5HT), ADP, and platelet factor 4. Hydrolysis of 5% phospholipids resulted in release of 70% 5HT. Platelet 5HT release was rapid, occurring within 2 min. Phospholipase C (0.2 U/ml) with Ca(++) (0.55 mM) also released 10.35 nmol sotrage pool ADP/10(9) platelets and 63% platelet factor 4 during 3 min. Phospholipase C did not cause leakage of cytoplasmic metabolic pool ADP, since only 6.6% [(3)H]ADP was released. Ultrastructural analysis of phospholipase C-modified platelets showed that platelets were intact. After 2% phospholipid hydrolysis, centralization of granules and contraction of microtubules were evident. After 18% phospholipid hydrolysis, there were morphological indications of degranulation. Phospholipase C-induced phospholipid hydrolysis caused the release of ADP and 5HT since: (a) Phospholipase C purified by heating was shown to be free of protease and neuraminidase activity and capable of inducing the platelet release reaction. (b) Antitoxin (Cl. perfringens) neutralized phospholipase C-induced 5HT release which rules out a contaminant. (c) Phosphorylcholine, the hydrolysis product, did not induce platelet 5HT release. This study demonstrates that minimal hydrolysis of platelet phospholipids triggers the release reaction. Our hypothesis is that phospholipids, presumably phosphatidylcholine, are situated at or near active site or \"receptor\" on the platelet surface and function as the modulator for the release reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371563"}
{"pmid": "4371566", "title": "The role of Clostridium perfringens in the growth response of chicks to dietary penicillin.", "content": "The role of Clostridium perfringens in the growth response of chicks to dietary penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371566"}
{"pmid": "4371565", "title": "The role of viruses in the etiology of cancer and leukemia.", "content": "The role of viruses in the etiology of cancer and leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371565"}
{"pmid": "4371567", "title": "A serological study of antibody to Epstein-Barr virus in an Australian population.", "content": "A serological study of antibody to Epstein-Barr virus in an Australian population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371567"}
{"pmid": "4371569", "title": "Hyperostosis corticalis generalisata familiaris.", "content": "Hyperostosis corticalis generalisata familiaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371569"}
{"pmid": "4371568", "title": "Chlorophyll b containing liposomes: effect of thermal transitions on catalytic and spectral properties.", "content": "Chlorophyll b containing liposomes: effect of thermal transitions on catalytic and spectral properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371568"}
{"pmid": "4371571", "title": "Superoxide dismutases.", "content": "Superoxide dismutases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371571"}
{"pmid": "4371572", "title": "Incorporation of lipid vesicles by mammalian cells provides a potential method for modifying cell behaviour.", "content": "Incorporation of lipid vesicles by mammalian cells provides a potential method for modifying cell behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371572"}
{"pmid": "4371573", "title": "Interrelationships among the levels of ATP, adenosine and cyclic AMP in incubated slices of guinea-pig cerebral cortex: effects of depolarizing agents, psychotropic drugs and metabolic inhibitors.", "content": "Interrelationships among the levels of ATP, adenosine and cyclic AMP in incubated slices of guinea-pig cerebral cortex: effects of depolarizing agents, psychotropic drugs and metabolic inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371573"}
{"pmid": "4371574", "title": "Interrelationships of pituitary and plasma corticotrophin and plasma corticosterone in adrenalectomized and stressed, adrenalectomized rats.", "content": "Interrelationships of pituitary and plasma corticotrophin and plasma corticosterone in adrenalectomized and stressed, adrenalectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371574"}
{"pmid": "4371575", "title": "Occurrence of carcinoma of the bile ducts: a brief review.", "content": "Occurrence of carcinoma of the bile ducts: a brief review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371575"}
{"pmid": "4371576", "title": "Reversible inhibition of poliovirus RNA synthesis in vivo and in vitro by viral products.", "content": "Reversible inhibition of poliovirus RNA synthesis in vivo and in vitro by viral products. In poliovirus-infected HeLa-S3 cells, the protease inhibitors tolylsulfonyl-phenylalanyl chloromethyl ketone and iodoacetamide cause an accumulation of large precursor proteins, and they block viral RNA synthesis most probably via these products. Viral RNA polymerase activity can, however, be extracted by detergent containing buffer (Tris/Nonidet P-40, deoxycholate) from the inhibited cells. Only cytoplasmic extracts from infected cells treated with tolylsulfonyl-phenylalanyl chloromethyl ketone or iodoacetamide contain a protein which inhibits the in vitro polymerase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371576"}
{"pmid": "4371577", "title": "Revertants and secondary arom-2 mutants induced in non-complementing mutants in the arom gene cluster of Neurospora crassa.", "content": "Revertants and secondary arom-2 mutants induced in non-complementing mutants in the arom gene cluster of Neurospora crassa. Extensive genetical and biochemical studies have been performed with revertants and secondary arom-2 mutants induced in two different primary non-complementing mutants which map within the arom gene cluster of Neurospora crassa. These studies indicate that mutant M54 but not M25 can revert by super-suppressor mutations in unlinked genes, thus confirming previous evidence that M54 contains a nonsense codon. At least three new super suppressors of M54 have been detected. All four super suppressors (including one previously detected) when combined with M54 result in high levels of all five of the arom enzymic activities in the form of arom multienzyme complexes very similar to (but not necessarily identical with) that in wild type (WT).-Evidence has also been obtained that the two non-complementing mutants can yield revertants which appear to result from true back mutations and produce arom aggregates essentially indistinguishable from that of WT. In addition, M25, but not M54, when plated on quinic acid yields revertants (secondary mutants) some of which are phenotypically indistinguishable from arom-2 primary mutants and others of which, although also mapping within the arom-2 gene, exhibit unusual properties. Genetic evidence indicates that the M25 secondary mutants are localized within the arom-2 gene, but that they arise from mutational events more complex than ones resulting in single base pair changes in the M25 codon.-The recovery of secondary arom-2 mutants as revertants of non-complementing arom mutants provides strong evidence, independent of earlier recombination data, that non-complementing arom mutants are located within the arom-2 structural gene of the arom gene cluster. In addition, the occurrence and characteristics of these secondary arom-2 mutants provide strong evidence, independent of the results with nonsense suppressors, that the arom gene cluster is transcribed, beginning with the arom-2 gene, as a single polycistronic messenger ribonucleic acid (mRNA) molecule which is subsequently translated into the arom multienzyme complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371577"}
{"pmid": "4371578", "title": "Hypertriglyceridemia and carbohydrate intolerance.", "content": "Hypertriglyceridemia and carbohydrate intolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371578"}
{"pmid": "4371580", "title": "Restructuring medical education for management of the chronically ill aged.", "content": "Restructuring medical education for management of the chronically ill aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371580"}
{"pmid": "4371579", "title": "Bilirubin UDP-glucosyl-and UDP-glucuronosyltransferase of rat liver. A comparative study of the effects of membrane perturbants in vitro and of chrysene administration in vivo.", "content": "Bilirubin UDP-glucosyl-and UDP-glucuronosyltransferase of rat liver. A comparative study of the effects of membrane perturbants in vitro and of chrysene administration in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371579"}
{"pmid": "4371581", "title": "Observations from longitudinal data on growth in stature and sitting height of children with Down's syndrome.", "content": "Observations from longitudinal data on growth in stature and sitting height of children with Down's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371581"}
{"pmid": "4371583", "title": "Observations on the resistance of Fpstein-Barr virus DNA synthesis to hydroxyurea.", "content": "Observations on the resistance of Fpstein-Barr virus DNA synthesis to hydroxyurea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371583"}
{"pmid": "4371584", "title": "A surveillance for Japanese encephalitis (JE) in pigs in southern Taiwan.", "content": "A surveillance for Japanese encephalitis (JE) in pigs in southern Taiwan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371584"}
{"pmid": "4371582", "title": "Observations on the action of type A botulinum toxin on frog neuromuscular junctions.", "content": "Observations on the action of type A botulinum toxin on frog neuromuscular junctions. 1. Progressive block of neuromuscular transmission in frog sartorius and gastrocnemius preparations by haemagglutinin-free crystalline Type A botulinum toxin (BTX) was investigated by in vitro application and by injection of the toxin into living animals.2. Neuromuscular block was characterized by (a) decline in amplitude of evoked twitch contractions, (b) decline in amplitudes of end-plate potentials (e.p.p.s) and (c) changes in statistical characteristics of spontaneous miniature end-plate potentials (m.e.p.p.s).3. Progress of the block was enhanced by nerve stimulation.4. A decrease in frequency to less than 0.1/sec and decreased average amplitudes of m.e.p.p.s preceded observable impairment of neuromuscular transmission. These changes occurred as early as 3 hr after injection of the toxin into dorsal lymph sacs.5. The amplitude distributions of m.e.p.p.s changed from a normal distribution to one that showed an increased skewness toward smaller amplitudes as the block progressed. These changes were first detectable as early as 75 min following addition of the toxin to the bath.6. At later stages of toxin action, e.p.p.s began to decrease in amplitude and eventually failed altogether. E.p.p.s showed a normal quantal variation at very early stages in the block in Mg(2+)-treated preparations. At later stages of the block, it was not possible to test the quantal make-up of the e.p.p.7. At all stages before complete failure it was possible to obtain normal or greater than normal degrees of synaptic facilitation with paired stimuli to the nerve. This aspect of the coupling of nerve terminal depolarization to transmitter release appears to be relatively unaffected by BTX.8. Electrical depolarization of nerve terminals in partially blocked preparations evoked a maintained discharge of m.e.p.p.s with an amplitude distribution similar to that of the spontaneous m.e.p.p.s; hyperpolarization of the terminals evokes a distinctly larger class of m.e.p.p.s. In fully blocked preparations, depolarization of the terminals does not evoke transmitter release whereas hyperpolarization continues to yield the larger class of m.e.p.p.s.9. It is proposed that the neuromuscular block caused by BTX is due to impairment of a process by which vesicles become charged with transmitter before release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371582"}
{"pmid": "4371585", "title": "Mucus-producing adenocarcinoma of renal pelvis.", "content": "Mucus-producing adenocarcinoma of renal pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371585"}
{"pmid": "4371586", "title": "Air sampling of smallpox virus.", "content": "Air sampling of smallpox virus. Airborne smallpox virus has been recovered in an isolation hospital using an adhesive surface sampling technique in the presence of very low aerosol concentrations. Previous work in this field is reviewed. Successful recovery of airborne virus depends on sampling large volumes of air with a suitable sampler and thorough investigation of the whole sample taken for the presence of viable virus. More information on the characteristics and behaviour of airborne smallpox virus is needed in particular with regard to the future design and siting of smallpox isolation units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371586"}
{"pmid": "4371587", "title": "Transcutaneous electrical stimulation for control of pain.", "content": "Transcutaneous electrical stimulation for control of pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371587"}
{"pmid": "4371588", "title": "The search for a viral agent in Hodgkin's disease.", "content": "The search for a viral agent in Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371588"}
{"pmid": "4371589", "title": "Viruses and brain tumors.", "content": "Viruses and brain tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371589"}
{"pmid": "4371591", "title": "The significance of a palpable liver. A correlation of clinical and radioisotope studies.", "content": "The significance of a palpable liver. A correlation of clinical and radioisotope studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371591"}
{"pmid": "4371592", "title": "The significance of cyclic 3'5-AMP for the Euler-Liljestrand mechanism.", "content": "The significance of cyclic 3'5-AMP for the Euler-Liljestrand mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371592"}
{"pmid": "4371594", "title": "A gosling disease in Viet-Nam.", "content": "A gosling disease in Viet-Nam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371594"}
{"pmid": "4371593", "title": "Translation products of foot-and-mouth disease virus-infected baby hamster kidney cells.", "content": "Translation products of foot-and-mouth disease virus-infected baby hamster kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371593"}
{"pmid": "4371595", "title": "Chiasma in the XY bivalent of the Chinese hamster.", "content": "Chiasma in the XY bivalent of the Chinese hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371595"}
{"pmid": "4371596", "title": "Transmitter-dependent changes of equilibrium characteristics of catecholamine synaptosomes in sucrose density gradients.", "content": "Transmitter-dependent changes of equilibrium characteristics of catecholamine synaptosomes in sucrose density gradients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371596"}
{"pmid": "4371599", "title": "Transport of sugars in tumor cell membranes.", "content": "Transport of sugars in tumor cell membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371599"}
{"pmid": "4371600", "title": "A possible relation between human pathogenicity of smallpox vaccines and virus growth at elevated temperatures.", "content": "A possible relation between human pathogenicity of smallpox vaccines and virus growth at elevated temperatures. Seven smallpox vaccines of known human pathogenicity were tested for their ability to produce pocks on the chick chorioallantois at 39.7 degrees C. Significant differences were found and the more pathogenic strains produced pocks with greater efficiency at 39.7 degrees C. than did strains of average or low pathogenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371600"}
{"pmid": "4371602", "title": "A test of osteoblasts for hematopoietic competence.", "content": "A test of osteoblasts for hematopoietic competence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371602"}
{"pmid": "4371606", "title": "The status of poliomyelitis in Venezuela.", "content": "The status of poliomyelitis in Venezuela.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371606"}
{"pmid": "4371607", "title": "The stereospecificity of the hydrogen transfer from (R)-carnitine to NAD, catalyzed by (R)-carnitine dehydrogenase from Pseudomonas aeruginosa.", "content": "The stereospecificity of the hydrogen transfer from (R)-carnitine to NAD, catalyzed by (R)-carnitine dehydrogenase from Pseudomonas aeruginosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371607"}
{"pmid": "4371608", "title": "The stimulation of calcium transport in cardiac sarcoplasmic reticulum by adenosine 3':5'-monophosphate-dependent protein kinase.", "content": "The stimulation of calcium transport in cardiac sarcoplasmic reticulum by adenosine 3':5'-monophosphate-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371608"}
{"pmid": "4371609", "title": "The stimulatory effect of a serum factor on DNA and protein synthesis in hepatoma cells.", "content": "The stimulatory effect of a serum factor on DNA and protein synthesis in hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371609"}
{"pmid": "4371610", "title": "The stimulus-secretion coupling of glucose-induced insulin release. XVI. A glucose-like and calcium-independent effect of cyclic AMP.", "content": "The stimulus-secretion coupling of glucose-induced insulin release. XVI. A glucose-like and calcium-independent effect of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371610"}
{"pmid": "4371611", "title": "Intestinal vasculitis in essential, mixed cryoglobulinemia.", "content": "Intestinal vasculitis in essential, mixed cryoglobulinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371611"}
{"pmid": "4371613", "title": "The synthesis and biological activity of 25,26-dihydroxy-cholecalciferol, a polar metabolite of vitamin D3.", "content": "The synthesis and biological activity of 25,26-dihydroxy-cholecalciferol, a polar metabolite of vitamin D3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371613"}
{"pmid": "4371605", "title": "The state of laboratory automation.", "content": "The state of laboratory automation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371605"}
{"pmid": "4371615", "title": "Short communications tissue culture of adult human adrenocortical cells.", "content": "Short communications tissue culture of adult human adrenocortical cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371615"}
{"pmid": "4371617", "title": "Short rib-polydactyly syndromes and related conditions.", "content": "Short rib-polydactyly syndromes and related conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371617"}
{"pmid": "4371616", "title": "Ergot intoxication: historical review and description of unusual clinical manifestations.", "content": "Ergot intoxication: historical review and description of unusual clinical manifestations. Clinical ergotism as seen today results almost exclusively from the excessive intake of ergotamine tartrate in the treatment of migraine headache. Although both gangrenous and convulsive symptoms are seen in naturally occurring ergotism resulting from the ingestion of fungus infected rye, only gangrenous ergotism has been reported following the excessive ingestion of ergotamine tartrate. The symptoms of both iatrogenic and naturally occurring ergotism appear to result from regional ischemia caused by ergot induced vasospasm. This report discribes experiences in the diagnosis and management of two patients with unusual manifestations of iatrogenic ergotism. One patient presented with ischemia of all extremities and bilateral foot drop probably due to ischemic damage to the common peroneal nerves, a finding not previously described in ergot intoxication. The foot drop totally resolved in several months following the discontinuation of ergot. A second patient presented with unilateral leg ischemia and transient monocular blindness, both of which resolved after discontinuation of ergot. Both patients displayed typical angiographic findings of ergotism. There is no convincing evidence that any treatment other than discontinuation of ergotamine is of benefit in the treatment of iatrogenic ergotism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371616"}
{"pmid": "4371619", "title": "Prostaglandin E1 and fever.", "content": "Prostaglandin E1 and fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371619"}
{"pmid": "4371620", "title": "Spontaneous deaths in rabbits resulting from gastric trichobezoars.", "content": "Spontaneous deaths in rabbits resulting from gastric trichobezoars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371620"}
{"pmid": "4371618", "title": "Excitability changes in crayfish motor neurone terminals.", "content": "Excitability changes in crayfish motor neurone terminals. 1. Changes in the post-activation excitability of crayfish motor nerve terminals were used to measure afterpotentials that might be related to facilitation of transmitter release.2. The refractory period is followed by a period of supernormal excitability in which the threshold of nerve terminals drops to about 70% of its pre-activation level at about 15 msec following an impulse. The threshold returns exponentially to its pre-activation level with a time constant of about 25 msec at 13 degrees C. Such a supernormal excitability is rarely seen in pre-terminal nerve branches or in the main axon.3. Following a brief high-frequency tetanus the peak of the supernormal excitability is greater than that following a single impulse. At low temperature this peak is reduced and delayed, and the decay rate of the supernormal excitability is prolonged with a Q(10) of about 2.5.4. Depolarization of nerve terminals decreases, and hyperpolarization increases, the magnitude of the post-activation supernormal excitability.5. The magnitude of the supernormal excitability depends on the external potassium concentration, but not on sodium. In low calcium the peak supernormal excitability is often reduced. High calcium concentration and manganese ions have no effect, but cobalt abolishes the supernormal excitability, and its effects are only slightly reversible. Both cobalt and manganese reversibly block neuromuscular transmission.6. Strophanthidin has no effect on the post-activation supernormal excitability, but proteolytic enzymes reduce or abolish it, and hyperosmotic solutions also affect it.7. It is suggested that the action potential is followed by a depolarizing afterpotential in nerve terminals which is caused by a transient increase in the potassium concentration around the terminals. There is no evidence that afterpotentials in nerve terminals are related to facilitation in any way.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371618"}
{"pmid": "4371621", "title": "Spontaneous recovery from severe rickets resembling pseudo-vitamin D deficiency rickets.", "content": "Spontaneous recovery from severe rickets resembling pseudo-vitamin D deficiency rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371621"}
{"pmid": "4371622", "title": "A mutant of Pseudomonas putida with altered regulation of the enzymes for degradation of phenol and cresols.", "content": "A mutant of Pseudomonas putida with altered regulation of the enzymes for degradation of phenol and cresols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371622"}
{"pmid": "4371623", "title": "Adaptation in Rhodopseudomonas spheroides.", "content": "Adaptation in Rhodopseudomonas spheroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371623"}
{"pmid": "4371624", "title": "Adaptation of influenza virus to growth in cultured murine methylcholanthrene induced tumors.", "content": "Adaptation of influenza virus to growth in cultured murine methylcholanthrene induced tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371624"}
{"pmid": "4371627", "title": "A detector tube for the analysis of methyl isocyanate in air or nitrogen purge gas;.", "content": "A detector tube for the analysis of methyl isocyanate in air or nitrogen purge gas;.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371627"}
{"pmid": "4371628", "title": "Two temperature-induced changes in mitochondrial membranes detected by spin labelling and enzyme kinetics.", "content": "Two temperature-induced changes in mitochondrial membranes detected by spin labelling and enzyme kinetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371628"}
{"pmid": "4371631", "title": "Hypothalamic nuclei of rats after head irradiation and adrenocortical hormone treatment.", "content": "Hypothalamic nuclei of rats after head irradiation and adrenocortical hormone treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371631"}
{"pmid": "4371632", "title": "Hypothalamus as an endocrine organ. II.", "content": "Hypothalamus as an endocrine organ. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371632"}
{"pmid": "4371640", "title": "A method for the detection of starch hydrolysis by bacteria.", "content": "A method for the detection of starch hydrolysis by bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371640"}
{"pmid": "4371641", "title": "A method for the determination of polyamines in cerebrospinal fluid.", "content": "A method for the determination of polyamines in cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371641"}
{"pmid": "4371639", "title": "Hypothesis: Inhibition of E prostaglandin-sensitive adenyl cyclase as the mechanism of morphine analgesia.", "content": "Hypothesis: Inhibition of E prostaglandin-sensitive adenyl cyclase as the mechanism of morphine analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371639"}
{"pmid": "4371642", "title": "Parathyroid hormone (PTH)-mediated rise in urinary cyclic AMP(UcAMP) during acute extracellular fluid (ECF) expansion natriuresis in man.", "content": "Parathyroid hormone (PTH)-mediated rise in urinary cyclic AMP(UcAMP) during acute extracellular fluid (ECF) expansion natriuresis in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371642"}
{"pmid": "4371643", "title": "Hepatic amoebiasis. A study of 32 cases in the Western Cape.", "content": "Hepatic amoebiasis. A study of 32 cases in the Western Cape.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371643"}
{"pmid": "4371644", "title": "Genetic analysis of mutations affecting growth of Saccharomyces cerevisiae at low temperature.", "content": "Genetic analysis of mutations affecting growth of Saccharomyces cerevisiae at low temperature. A large number of genes control growth of the yeast Saccharomyces cerevisiae at low temperatures (< 10 degrees ). Approximately 47 percent of the mutants selected for inability to grow at 4-5 degrees C show increased sensitivity to cycloheximide. In 3 of 4 cases tested, supersensitivity to cycloheximide and inability to grow at the low temperature segregate together and thus appear to be effects of the same mutation. Since many cold-sensitive mutants of bacteria have been found to have altered ribosomes and since cycloheximide resistance in yeast can be caused by ribosomal changes, this suggests that the mutants having low-temperature-sensitive growth may be defective in ribosome-assembly processes at the low temperatures. Two of the lts loci, lts1 and lts3 have been located on chromosome VII and another two, lts4 and lts10 on chromosome IV. A mutation, cyh10, conferring cycloheximide resistance, but not cold sensitivity, has been located close to the centromere on chromosome II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371644"}
{"pmid": "4371645", "title": "Kinetic approach to the development in beta-lactam antibiotics. I. Comparative stability of semisynthetic penicllins and 6-aminopenicillanic acid in aqueous solution.", "content": "Kinetic approach to the development in beta-lactam antibiotics. I. Comparative stability of semisynthetic penicllins and 6-aminopenicillanic acid in aqueous solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371645"}
{"pmid": "4371647", "title": "Hepatic copper-and zinc-binding proteins in ruminants. 1. Distribution of Cu and Zn among soluble proteins of livers of varying Cu and Zn content.", "content": "Hepatic copper-and zinc-binding proteins in ruminants. 1. Distribution of Cu and Zn among soluble proteins of livers of varying Cu and Zn content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371647"}
{"pmid": "4371646", "title": "Somatic cell hybrids between mouse peritoneal macrophages and SV40-transformed human cells. I. Positive control of the transformed phenotype by the human chromosome 7 carrying the SV40 genome.", "content": "Somatic cell hybrids between mouse peritoneal macrophages and SV40-transformed human cells. I. Positive control of the transformed phenotype by the human chromosome 7 carrying the SV40 genome. Fusion of mouse peritoneal macrophages with SV40-transformed human cells, deficient in hypoxanthine guanine phosphoribosyltransferase, resulted in the formation of transformed somatic cell hybrids which contained, without exception, the human chromosome 7 carrying the SV40 genome. It is postulated that the hybridization of mouse nondividing cells with human cancer cells could permit the identification of the human \"oncogenic\" chromosome(s) present in human cancer cells, since such chromosome(s) should be retained by the totality of the mouse-human hybrid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371646"}
{"pmid": "4371648", "title": "Genetic manipulation of an abnormal jump response in Drosophila.", "content": "Genetic manipulation of an abnormal jump response in Drosophila. The hyperkinetic mutants, Hk(1) and Hk(2), jump and fall over when an object moves near them. This behavior, the kinetogenic response, has been measured by the experimenter moving his hand above a vial containing a single fly and scoring the number of positive responses in fifty trials. The response is higher in Hk(1) than in Hk(2) and has remained so over a period of several years and in different genetic backgrounds. The Hk(1)/Hk(2) heterozygote also responds to movements, establishing the allelism of the two mutants.-When Sh(5), a shaker mutant at another locus on the X chromosome, is introduced into the same chromosome as Hk(1) or Hk(2), the response is reduced in proportion to the number of Sh(5) mutant genes added.-When Hk(1) or Hk(2) is heterozygous with a deficiency for the hyperkinetic region of the X chromosome, the expression is more abnormal than the respective Hk(1) or Hk(2) homozygote. This shows that the mutant genes are producing an altered gene product, or less of the normal, since one mutant gene by itself has a more abnormal expression than two. A tentative explanation has been offered for the observed mutant behaviors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371648"}
{"pmid": "4371650", "title": "Kinetics of allosteric enzymes.", "content": "Kinetics of allosteric enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371650"}
{"pmid": "4371649", "title": "Kinetic regulation of adenylate kinases from muscle, liver, and hepatoma.", "content": "Kinetic regulation of adenylate kinases from muscle, liver, and hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371649"}
{"pmid": "4371651", "title": "Kinetics of ligand-binding and oxidation-reduction reactions of cytochrome c from horse heart and Candida krusei.", "content": "Kinetics of ligand-binding and oxidation-reduction reactions of cytochrome c from horse heart and Candida krusei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371651"}
{"pmid": "4371652", "title": "Kinetics of pyrophosphate-ATP exchange catalysed by L-tryptophan: tRNA ligase from Escherichia coli.", "content": "Kinetics of pyrophosphate-ATP exchange catalysed by L-tryptophan: tRNA ligase from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371652"}
{"pmid": "4371653", "title": "Deletion analysis of two nonessential regions of the T4 genome.", "content": "Deletion analysis of two nonessential regions of the T4 genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371653"}
{"pmid": "4371654", "title": "Function and structure of plasma lipoproteins.", "content": "Function and structure of plasma lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371654"}
{"pmid": "4371655", "title": "Rotational and translational diffusion in membranes.", "content": "Rotational and translational diffusion in membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371655"}
{"pmid": "4371656", "title": "Functional correlates of dopamine neurotransmission.", "content": "Functional correlates of dopamine neurotransmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371656"}
{"pmid": "4371657", "title": "Functional development of the autonomic innervation of the human fetal heart.", "content": "Functional development of the autonomic innervation of the human fetal heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371657"}
{"pmid": "4371658", "title": "Fractionation and molecular weight determination of deoxyribonucleic acid fragments using agarose column chromatography.", "content": "Fractionation and molecular weight determination of deoxyribonucleic acid fragments using agarose column chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371658"}
{"pmid": "4371659", "title": "Fractionation of islet tissue in processing proinsulin to insulin.", "content": "Fractionation of islet tissue in processing proinsulin to insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371659"}
{"pmid": "4371660", "title": "Relationship between SMON virus and avian infectious laryngotracheitis virus.", "content": "Relationship between SMON virus and avian infectious laryngotracheitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371660"}
{"pmid": "4371663", "title": "Quantitation of endogenous C-type virion production in several murine cell lines.", "content": "Quantitation of endogenous C-type virion production in several murine cell lines. Quantitation by enumeration of virion particles, measurement of absorbancy at 260 nm, and densitometry on sodium dodecyl sulfate-polyacrylamide gels has shown that mouse L-M cells yielded 7- to 10-fold less endogenous C-type virions than the parental lines, L or L929. The previously noted stimulation of L-M cell virion production by a concomitant 10% increase in fetal calf serum concentration (D. A. Kindig, R. Karp, and W. H. Kirsten, 1968), was not observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371663"}
{"pmid": "4371665", "title": "Hepatitis and brain lesions due to mouse hepatitis virus accompanied by wasting in nude mice.", "content": "Hepatitis and brain lesions due to mouse hepatitis virus accompanied by wasting in nude mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371665"}
{"pmid": "4371664", "title": "Quantitative genetic studies of the human plasma Lp(a) lipoprotein.", "content": "Quantitative genetic studies of the human plasma Lp(a) lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371664"}
{"pmid": "4371668", "title": "Hepatitis-associated antigen, cirrhosis and hepatoma in Rhodesia.", "content": "Hepatitis-associated antigen, cirrhosis and hepatoma in Rhodesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371668"}
{"pmid": "4371666", "title": "Hepatitis following actinomycin D and irradiation.", "content": "Hepatitis following actinomycin D and irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371666"}
{"pmid": "4371667", "title": "Hepatitis A: in vitro isolation of an agent with unusual growth requirements from a clinical case occurring in Costa Rica.", "content": "Hepatitis A: in vitro isolation of an agent with unusual growth requirements from a clinical case occurring in Costa Rica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371667"}
{"pmid": "4371669", "title": "Relative dependence on intracellular cyclic adenosine-3',5'-monophosphate levels of catabolite repressible proteins in Escherichia coli.", "content": "Relative dependence on intracellular cyclic adenosine-3',5'-monophosphate levels of catabolite repressible proteins in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371669"}
{"pmid": "4371670", "title": "Positive mediastinoscopy. An ominous finding.", "content": "Positive mediastinoscopy. An ominous finding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371670"}
{"pmid": "4371672", "title": "Treatment of childhood asthma for 13 months and longer with beclomethasone dipropionate aerosol.", "content": "Treatment of childhood asthma for 13 months and longer with beclomethasone dipropionate aerosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371672"}
{"pmid": "4371671", "title": "Reactivity of chick embryo heart to cholinergic agonists during ontogenesis: decline in desensitization at the onset of cholinergic transmission.", "content": "Reactivity of chick embryo heart to cholinergic agonists during ontogenesis: decline in desensitization at the onset of cholinergic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371671"}
{"pmid": "4371674", "title": "Symptomatic porphyria. I. The pathology of the liver in human symptomatic porphyria.", "content": "Symptomatic porphyria. I. The pathology of the liver in human symptomatic porphyria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371674"}
{"pmid": "4371675", "title": "Symptomatic porphyria. II. Hepatic changes with hexachlorobenzene.", "content": "Symptomatic porphyria. II. Hepatic changes with hexachlorobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371675"}
{"pmid": "4371679", "title": "Somatostatin inhibition of rat growth hormone release in vitro in the presence of BaCl2 or 3-isobutyl-1-methylxanthine.", "content": "Somatostatin inhibition of rat growth hormone release in vitro in the presence of BaCl2 or 3-isobutyl-1-methylxanthine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371679"}
{"pmid": "4371680", "title": "Spectral and catalytic properties of cytochrome P-450 from a diazinon-resistant housefly strain.", "content": "Spectral and catalytic properties of cytochrome P-450 from a diazinon-resistant housefly strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371680"}
{"pmid": "4371681", "title": "Spectral resolution of four cytochrome b components in mitochondria.", "content": "Spectral resolution of four cytochrome b components in mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371681"}
{"pmid": "4371684", "title": "Clostridium perfringens in the environment.", "content": "Clostridium perfringens in the environment. Clostridium perfringens was isolated from samples collected in Puget Sound in the state of Washington and areas considered as possible sources of these organisms to Puget Sound. The distribution of C. perfringens in the total Clostridium population was determined for fish gut contents and sediments collected in highly polluted and less polluted areas, sewage samples, freshwater sediments, and soils. The greatest numbers of C. perfringens were obtained from marine sediments collected near the sewage outfall at West Point. Fewer isolates were made from fish collected from less polluted stations, although the number of C. perfringens remained high in sediments from other Puget Sound stations. The proportion of C. perfringens in the total Clostridium populations varied between 56 and 71% for sewage samples and only 0.4 to 4.1% for freshwater sediments and soil samples. Only 25 C. perfringens isolates out of 137 from fish guts, or 18%, were identifiable serologically and these fell into 12 groups. C. perfringens were fed to fish and the fish were sacrificed after varying lengths of time. The number of C. perfringens increased slightly in the gut during the first 24 h and then the numbers decreased rapidly for the next 120 h.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371684"}
{"pmid": "4371685", "title": "Electron microscopic demonstration of insulin receptors on adipocyte plasma membranes utilizing a ferritin-insulin conjugate.", "content": "Electron microscopic demonstration of insulin receptors on adipocyte plasma membranes utilizing a ferritin-insulin conjugate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371685"}
{"pmid": "4371686", "title": "Electron microscopic observations on infectious bovine rhinotracheitis virus in bovine fetal tracheal organ cultures.", "content": "Electron microscopic observations on infectious bovine rhinotracheitis virus in bovine fetal tracheal organ cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371686"}
{"pmid": "4371688", "title": "Electron spin resonance of manganese(II)-substituted zinc(II) metalloenzymes.", "content": "Electron spin resonance of manganese(II)-substituted zinc(II) metalloenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371688"}
{"pmid": "4371687", "title": "Electron microscopy of single-stranded RNA from vesicular stomatitis virus.", "content": "Electron microscopy of single-stranded RNA from vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371687"}
{"pmid": "4371683", "title": "Electrical activity of gastrointestinal smooth muscle.", "content": "Electrical activity of gastrointestinal smooth muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371683"}
{"pmid": "4371689", "title": "Electron spin resonance spectra from whole blood of cancer patients.", "content": "Electron spin resonance spectra from whole blood of cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371689"}
{"pmid": "4371691", "title": "Electron-spin resonance of an X-irradiated single crystal of N-acetyl-DL-valine.", "content": "Electron-spin resonance of an X-irradiated single crystal of N-acetyl-DL-valine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371691"}
{"pmid": "4371690", "title": "Electron-paramagnetic-resonance studies on cobalt(II) carbonic anhydrase. Low-spin cyanide complexes.", "content": "Electron-paramagnetic-resonance studies on cobalt(II) carbonic anhydrase. Low-spin cyanide complexes. The low-spin cyanide complexes of three Co(II) carbonic anhydrases were investigated by electron paramagnetic resonance (e.p.r.) at 9 and 35GHz. Well-defined and closely axial spectra were obtained only in the absence of oxygen. Several mole equivalents of cyanide were required for complete formation of the complexes in frozen solution, although large excesses caused abstraction of the cobalt. Experiments with [(13)C]cyanide showed that the low-spin complexes contained two CN(-) groups in an environment similar to that of the in-plane ligands in [Co(CN)(5)](3-). A combined e.p.r. and spectrophotometric titration confirmed the presence of two CN(-) ligands. A 5-co-ordinate square pyramidal structure involving three protein ligands was proposed. The dicyanide complex could be oxygenated reversibly, producing a characteristic new e.p.r. spectrum. The O(2) molecule was thought to occupy the remaining octahedral metal site in a formally Co(III) species. The optical spectrum of the dicyanide lacked the prominent d-d bands of the high-spin monocyanide. Both e.p.r. and optical data indicated that the low-spin complex was formed much more fully in frozen solution than at room temperature. Differences in behaviour between the high- and low-activity enzymes suggested some variation in conformational flexibility at the metal binding site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371690"}
{"pmid": "4371692", "title": "The trophic responses of cultured adrenocortical cells to ACTH.", "content": "The trophic responses of cultured adrenocortical cells to ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371692"}
{"pmid": "4371693", "title": "Electrophoretic polymorphism of adenylate kinase in human jejunum.", "content": "Electrophoretic polymorphism of adenylate kinase in human jejunum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371693"}
{"pmid": "4371694", "title": "An attempt to identify putative neurotransmitter substance released from the non-adrenergic inhibitory fibers in the vagal supply to the guinea-pig stomach.", "content": "An attempt to identify putative neurotransmitter substance released from the non-adrenergic inhibitory fibers in the vagal supply to the guinea-pig stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371694"}
{"pmid": "4371695", "title": "An attempt to localize cyclic phosphodiesterase at adrenergic nerve endings.", "content": "An attempt to localize cyclic phosphodiesterase at adrenergic nerve endings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371695"}
{"pmid": "4371697", "title": "Denaturation of the normal and abnormal hemoglobin molecule.", "content": "Denaturation of the normal and abnormal hemoglobin molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371697"}
{"pmid": "4371698", "title": "Dibutyryl cyclic adenosine 3',5-monophosphate and brain lipid metabolism.", "content": "Dibutyryl cyclic adenosine 3',5-monophosphate and brain lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371698"}
{"pmid": "4371700", "title": "Evaluation of serum dopamine-beta-hydroxylase activity as an index of sympathetic nervous activity in man.", "content": "Evaluation of serum dopamine-beta-hydroxylase activity as an index of sympathetic nervous activity in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371700"}
{"pmid": "4371699", "title": "Evaluation of a plaque assay for the maedi-progressive pneumonia-visna viruses.", "content": "Evaluation of a plaque assay for the maedi-progressive pneumonia-visna viruses. A simple and direct plaque assay for maedi virus, two strains of progressive pneumonia virus, and two strains of visna virus has been developed and evaluated. The technique allows the plaques formed by these viruses to be localized without disturbing the host-cell substrate of sheep choroid plexus cells or the gelled maintenance medium over the host-cell monolayer. Diethylaminoethyl-dextran supplementation of the medium used to overlay strain K796 visna virus-infected cultures decreases the time required for maximum plaque development from 12 to 10 days, enhances the contrast of the plaques, increases the titer of plaque-forming units, and permits a plaque size heterogeneity to be realized. Both large and small plaques occur in cultures infected with the visna viruses, one strain of progressive pneumonia virus, or maedi virus. In contrast, the plaques observed in cultures infected with the second strain of progressive pneumonia virus are relatively homogeneous in size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371699"}
{"pmid": "4371701", "title": "Production and localization of the secretory component in tumours of the exocrine glands.", "content": "Production and localization of the secretory component in tumours of the exocrine glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371701"}
{"pmid": "4371703", "title": "Production of sindbis, influenza, and vesicular stomatitis viruses in chicken embryo and rat embryo cell suspensions.", "content": "Production of sindbis, influenza, and vesicular stomatitis viruses in chicken embryo and rat embryo cell suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371703"}
{"pmid": "4371705", "title": "A study of the relationships between carbon tetrachloride-induced lipid peroxidation and liver damage in rats pretreated with vitamin E.", "content": "A study of the relationships between carbon tetrachloride-induced lipid peroxidation and liver damage in rats pretreated with vitamin E.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371705"}
{"pmid": "4371707", "title": "A study of urolithiasis in grazing ruminants in South Australia.", "content": "A study of urolithiasis in grazing ruminants in South Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371707"}
{"pmid": "4371706", "title": "A study of tumors of the parapharyngeal space.", "content": "A study of tumors of the parapharyngeal space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371706"}
{"pmid": "4371709", "title": "Tissue sensitivity to drugs in disease states.", "content": "Tissue sensitivity to drugs in disease states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371709"}
{"pmid": "4371708", "title": "Tissue androgens and androphilic proteins in rat epididymis during sexual development.", "content": "Tissue androgens and androphilic proteins in rat epididymis during sexual development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371708"}
{"pmid": "4371710", "title": "Influence of adrenal steroids on liver enzymes of neonatally castrated rats.", "content": "Influence of adrenal steroids on liver enzymes of neonatally castrated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371710"}
{"pmid": "4371711", "title": "Influence of corticotrophic and corticosteroid hormones on the output of cells from the popliteal lymph node of the sheep.", "content": "Influence of corticotrophic and corticosteroid hormones on the output of cells from the popliteal lymph node of the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371711"}
{"pmid": "4371712", "title": "Influence of immunosuppressive drugs on replication of Col MM virus and productive of interferon in vivo.", "content": "Influence of immunosuppressive drugs on replication of Col MM virus and productive of interferon in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371712"}
{"pmid": "4371713", "title": "Influence of membrane phosphatidylinositol content on the activity of bovine brain phospholipid transfer protein.", "content": "Influence of membrane phosphatidylinositol content on the activity of bovine brain phospholipid transfer protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371713"}
{"pmid": "4371715", "title": "Influence of the socio-economic level on the conception rate during lactation.", "content": "Influence of the socio-economic level on the conception rate during lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371715"}
{"pmid": "4371714", "title": "Influence of the hormonal forms of ACTH on the pattern of corticosteroid secretion.", "content": "Influence of the hormonal forms of ACTH on the pattern of corticosteroid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371714"}
{"pmid": "4371716", "title": "Cellular and humoral immune interactions during neoplastic development.", "content": "Cellular and humoral immune interactions during neoplastic development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371716"}
{"pmid": "4371717", "title": "Granular cells and granular cell lesions.", "content": "Granular cells and granular cell lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371717"}
{"pmid": "4371718", "title": "Cellular distribution of nicotinamide adenine dinucleotide glycohydrolase in the central nervous system.", "content": "Cellular distribution of nicotinamide adenine dinucleotide glycohydrolase in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371718"}
{"pmid": "4371721", "title": "Stimulation of hepatic triglyceride synthesis and secretion by clofibrate.", "content": "Stimulation of hepatic triglyceride synthesis and secretion by clofibrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371721"}
{"pmid": "4371722", "title": "Stimulation of mitochondrial DNA synthesis as an early function of herpes simplex virus.", "content": "Stimulation of mitochondrial DNA synthesis as an early function of herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371722"}
{"pmid": "4371725", "title": "Stimulation of thymidine kinase induction by polyoma virus in cells \"prelabeled\" with 5-bromo-2'-deoxyuridine.", "content": "Stimulation of thymidine kinase induction by polyoma virus in cells \"prelabeled\" with 5-bromo-2'-deoxyuridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371725"}
{"pmid": "4371723", "title": "Stimulation of ribosomal and DNA-like RNA synthesis by alpha-methyltryptophan.", "content": "Stimulation of ribosomal and DNA-like RNA synthesis by alpha-methyltryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371723"}
{"pmid": "4371724", "title": "Stimulation of the posterior columns of the spinal cord for pain control: indications, technique, and results.", "content": "Stimulation of the posterior columns of the spinal cord for pain control: indications, technique, and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371724"}
{"pmid": "4371726", "title": "The ultrastructure of cytoplasmic inclusions in circulating lymphocytes in canine distemper.", "content": "The ultrastructure of cytoplasmic inclusions in circulating lymphocytes in canine distemper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371726"}
{"pmid": "4371727", "title": "The ultrastructure of neuroblastoma glioma somatic cell hybrids. Expression of neuronal characteristics stimulated by dibutyryl adenosine 3',5' cyclic monophosphate.", "content": "The ultrastructure of neuroblastoma glioma somatic cell hybrids. Expression of neuronal characteristics stimulated by dibutyryl adenosine 3',5' cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371727"}
{"pmid": "4371729", "title": "Conjunctival bacterial flora of the clinically normal New Zealand white rabbit.", "content": "Conjunctival bacterial flora of the clinically normal New Zealand white rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371729"}
{"pmid": "4371735", "title": "Failure of cytochrome C to cure experimental Amanita phalloides poisoning.", "content": "Failure of cytochrome C to cure experimental Amanita phalloides poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371735"}
{"pmid": "4371736", "title": "Failure to demonstrate serotonergic neurons in the myenteric plexus of the rat.", "content": "Failure to demonstrate serotonergic neurons in the myenteric plexus of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371736"}
{"pmid": "4371737", "title": "Tumours and dysplasias of the mammary gland.", "content": "Tumours and dysplasias of the mammary gland. As mammary tumours occur frequently in the dog and cat but rarely in other domestic animals, only the tumours of these two species are classified. The epithelial tumours are termed \"complex\" when they consist of cells resembling both secretory and myoepithelial cells: these tumours are biologically less malignant than tumours of the \"simple\" type in which only one of these kinds of cell is present. The carcinomas are subdivided into adenocarcinoma, solid carcinoma, spindle cell carcinoma, anaplastic carcinoma, squamous cell carcinoma, and mucinous carcinoma. The term \"carcinosarcoma or malignant mixed tumour\" was used only when there were cells morphologically resembling not only one or both of the epithelial components but also connective tissue cells with their products of differentiation. The benign tumours are classed as adenoma, papilloma, fibroadenoma, or benign soft tissue tumour. The dysplasias are described under the following headings: cyst, adenosis, regular typical epithelial proliferation in ducts and lobules (epitheliosis), duct ectasia, fibrosclerosis, and lobular hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371737"}
{"pmid": "4371738", "title": "Tumours of the lung.", "content": "Tumours of the lung. Lung tumours are not common in domestic animals; there has not been the increase in epidermoid carcinomas and anaplastic small-cell carcinomas that has occurred in man this century. Adenocarcinoma is the most common type in animals. The biological behaviour of each type of tumour in animals seems to be much the same as in man. The tumours are described histologically, the main categories being: epidermoid carcinoma, anaplastic carcinoma, adenocarcinoma, combined epidermoid and adenocarcinoma, carcinoid tumours, bronchial gland tumours, benign tumours, and sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371738"}
{"pmid": "4371739", "title": "Tumours of the nervous system.", "content": "Tumours of the nervous system. Tumours of the nervous system of animals are not as rare as has been commonly believed. In dogs, especially the brachycephalic breeds, these tumours occur as frequently as in man. The tumours are grouped according to tissue of origin as follows: nerve cells, neuroepithelium, glia, peripheral nerves and nerve sheaths, meninges and vessels, the pineal and pituitary glands, and the craniopharyngeal duct. Tumours of the glia are relatively common and are divided into the following types: astrocytoma, oligodendroglioma, glioblastoma, spongioblastoma, medulloblastoma, and unclassified gliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371739"}
{"pmid": "4371740", "title": "Tumours of the soft (mesenchymal) tissues.", "content": "Tumours of the soft (mesenchymal) tissues. This is a classification of tumours of fibrous tissue, fat, muscle, blood and lymph vessels, and mast cells, irrespective of the region of the body in which they arise. Tumours of fibrous tissue are divided into fibroma, fibrosarcoma (including \"canine haemangiopericytoma\"), other sarcomas, equine sarcoid, and various tumour-like lesions. The histological appearance of the tumours is described and illustrated with photographs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371740"}
{"pmid": "4371741", "title": "Tumours of the urinary bladder.", "content": "Tumours of the urinary bladder. Tumours of the urinary bladder are uncommon in all domestic animals except cattle in certain regions. Where cattle eat bracken (Pteridium aquilinum) there is a high incidence of these tumours. Epithelial tumours are the most frequently encountered neoplasms in cattle and in dogs-the two species most studied. They are described under the following names: papilloma, adenoma, transitional cell carcinoma (with variants), squamous cell carcinoma, adenocarcinoma, and undifferentiated carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371741"}
{"pmid": "4371742", "title": "Status of the endogenous avian leukosis virus in resistant cells from a producing line.", "content": "Status of the endogenous avian leukosis virus in resistant cells from a producing line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371742"}
{"pmid": "4371743", "title": "The use of continuous preparative free-flow electrophoresis for dissociating cell fractions and isolation of membranous components.", "content": "The use of continuous preparative free-flow electrophoresis for dissociating cell fractions and isolation of membranous components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371743"}
{"pmid": "4371744", "title": "The use of non-professional change agents in an institution.", "content": "The use of non-professional change agents in an institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371744"}
{"pmid": "4371745", "title": "The use of oestrogen-progestogen preparations in the treatment of hirsutism in the female.", "content": "The use of oestrogen-progestogen preparations in the treatment of hirsutism in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371745"}
{"pmid": "4371746", "title": "The use of BSVR-SrCr mice for detection of murine strains of toxigenic Escherichia coli.", "content": "The use of BSVR-SrCr mice for detection of murine strains of toxigenic Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371746"}
{"pmid": "4371733", "title": "Disruption of drinking to intracranial angiotensin by a lateral hypothalamic lesion.", "content": "Disruption of drinking to intracranial angiotensin by a lateral hypothalamic lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371733"}
{"pmid": "4371747", "title": "The use of CI 744 as an anesthetic for laboratory animals.", "content": "The use of CI 744 as an anesthetic for laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371747"}
{"pmid": "4371748", "title": "Computerized primate information retrieval system (PIRS).", "content": "Computerized primate information retrieval system (PIRS).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371748"}
{"pmid": "4371749", "title": "The validity of comparing the measurements of angiotensin I generated in human plasma by radioimmunoassay and bioassay.", "content": "The validity of comparing the measurements of angiotensin I generated in human plasma by radioimmunoassay and bioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371749"}
{"pmid": "4371750", "title": "Salivary gland scintiphotography.", "content": "Salivary gland scintiphotography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371750"}
{"pmid": "4371751", "title": "Renovascular hypertension. A clinical and laboratory study.", "content": "Renovascular hypertension. A clinical and laboratory study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371751"}
{"pmid": "4371753", "title": "Pryuvate as substrate in the determination of serum lactate dehydrogenase isoenzyme activity.", "content": "Pryuvate as substrate in the determination of serum lactate dehydrogenase isoenzyme activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371753"}
{"pmid": "4371752", "title": "The vasopressin-sensitive adenylate cyclase of the rat kidney. Effect of adrenalectomy and corticosteroids on hormonal receptor-enzyme coupling.", "content": "The vasopressin-sensitive adenylate cyclase of the rat kidney. Effect of adrenalectomy and corticosteroids on hormonal receptor-enzyme coupling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371752"}
{"pmid": "4371754", "title": "Pyruvate carboxylase from chicken liver. Magnetic resonance studies of the effect of substrates and inhibitors on the environment of the bound manganese.", "content": "Pyruvate carboxylase from chicken liver. Magnetic resonance studies of the effect of substrates and inhibitors on the environment of the bound manganese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371754"}
{"pmid": "4371755", "title": "Activation and dissociation of adenosine 3'-5'-monophosphate-dependent and guanosine 3'-5'-monophosphate-dependent protein kinases by various cyclic nucleotide analogs.", "content": "Activation and dissociation of adenosine 3'-5'-monophosphate-dependent and guanosine 3'-5'-monophosphate-dependent protein kinases by various cyclic nucleotide analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371755"}
{"pmid": "4371757", "title": "Active transport of exogenous S-adenosylmethionine and related compounds into cells and vacuoles of Saccharomyces cerevisiae.", "content": "Active transport of exogenous S-adenosylmethionine and related compounds into cells and vacuoles of Saccharomyces cerevisiae. Saccharomyces cerevisiae 4094-B (alpha, ade-2, ura-1) in potassium phosphate buffer with glucose under aerobic conditions took up (-)S-adenosyl-l-methionine from the medium in sufficient quantity to permit the demonstration of its accumulation in the vacuole by ultraviolet micrography. The same result was obtained with (+/-)S-adenosyl-l-methionine, (+/-)S-adenosyl-d-methionine, and (-)S-adenosyl-l-ethionine. The rate of uptake was slow with (-)S-adenosyl-S(n-propyl)-l-homocysteine and S-adenosyl-d-homocysteine. S-Adenosyl-l-homocysteine was assimilated rapidly, but intracellular degradation precluded accumulation and ultraviolet micrographic studies. The uptake of 5'-methyl-, 5'-ethyl-, 5'-n-propylthioadenosine, and 5'-dimethylsulfonium adenosine was minimal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371757"}
{"pmid": "4371756", "title": "Activation of lipoprotein lipase in vitro by unsaturated phospholipids.", "content": "Activation of lipoprotein lipase in vitro by unsaturated phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371756"}
{"pmid": "4371758", "title": "A novel respiration-deficient mutant of Saccharomyces cerevisiae. I. Preliminary characterization of phenotype and mitochondrial inheritance.", "content": "A novel respiration-deficient mutant of Saccharomyces cerevisiae. I. Preliminary characterization of phenotype and mitochondrial inheritance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371758"}
{"pmid": "4371760", "title": "Recovery of herpes simplex virus from human sacral ganglions.", "content": "Recovery of herpes simplex virus from human sacral ganglions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371760"}
{"pmid": "4371759", "title": "Recovery of adenoviruses and slow herpesviruses from horses having respiratory tract infection.", "content": "Recovery of adenoviruses and slow herpesviruses from horses having respiratory tract infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371759"}
{"pmid": "4371761", "title": "Recovery of DNA-dependent RNA polymerase activities from L cells after mengovirus infection.", "content": "Recovery of DNA-dependent RNA polymerase activities from L cells after mengovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371761"}
{"pmid": "4371762", "title": "Synovial sarcoma arising from the lower end of the femur.", "content": "Synovial sarcoma arising from the lower end of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371762"}
{"pmid": "4371763", "title": "Synovial sarcoma of the head and neck.", "content": "Synovial sarcoma of the head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371763"}
{"pmid": "4371764", "title": "Synovial sarcoma of the tongue, report of a case.", "content": "Synovial sarcoma of the tongue, report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371764"}
{"pmid": "4371766", "title": "Behavioral manifestations of competition of retinal endings for sites in doubly innervated frog optic tectum.", "content": "Behavioral manifestations of competition of retinal endings for sites in doubly innervated frog optic tectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371766"}
{"pmid": "4371765", "title": "Behavioral effects of direct- and indirect-acting dopaminergic agonists.", "content": "Behavioral effects of direct- and indirect-acting dopaminergic agonists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371765"}
{"pmid": "4371767", "title": "Behavioral modulation of the cardiovascular effects of l-norepinephrine in the squirrel monkey.", "content": "Behavioral modulation of the cardiovascular effects of l-norepinephrine in the squirrel monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371767"}
{"pmid": "4371768", "title": "Behaviour of flagella isolated from Crithidia oncopelti.", "content": "Behaviour of flagella isolated from Crithidia oncopelti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371768"}
{"pmid": "4371770", "title": "Activity of reduced ubiquinone: cytochrome c oxidoreductase with various ubiquinol-isoprenologues as substrate and corresponding inhibitory effect of antimycin in yeast.", "content": "Activity of reduced ubiquinone: cytochrome c oxidoreductase with various ubiquinol-isoprenologues as substrate and corresponding inhibitory effect of antimycin in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371770"}
{"pmid": "4371771", "title": "A new approach for selecting patients with metastatic breast cancer for hypophysectomy.", "content": "A new approach for selecting patients with metastatic breast cancer for hypophysectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371771"}
{"pmid": "4371769", "title": "Behaviour of rat-liver mitochondria during centrifugation in a sucrose gradient.", "content": "Behaviour of rat-liver mitochondria during centrifugation in a sucrose gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371769"}
{"pmid": "4371772", "title": "A new class of lipopolysaccharide from Thermoplasma acidophilum.", "content": "A new class of lipopolysaccharide from Thermoplasma acidophilum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371772"}
{"pmid": "4371773", "title": "A new fluorimetric procedure for the detection and quantitation of organic compounds in thin-layer chromatography.", "content": "A new fluorimetric procedure for the detection and quantitation of organic compounds in thin-layer chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371773"}
{"pmid": "4371774", "title": "A low molecular weight ruthenium complex inhibitory to mitochondrial Ca2+ transport.", "content": "A low molecular weight ruthenium complex inhibitory to mitochondrial Ca2+ transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371774"}
{"pmid": "4371775", "title": "A new, sensitive detector for liquid chromatography: the spray impact detector.", "content": "A new, sensitive detector for liquid chromatography: the spray impact detector.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371775"}
{"pmid": "4371777", "title": "An examination of the metabolism of thiamin by rat liver alcohol dehydrogenase.", "content": "An examination of the metabolism of thiamin by rat liver alcohol dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371777"}
{"pmid": "4371778", "title": "Autoxidation as a cause of antibacterial activity in unsaturated fatty acids.", "content": "Autoxidation as a cause of antibacterial activity in unsaturated fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371778"}
{"pmid": "4371779", "title": "An extracellular nuclease from suspension cultures of tobacco.", "content": "An extracellular nuclease from suspension cultures of tobacco.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371779"}
{"pmid": "4371780", "title": "On extraction of acyl and alkyl dihydroxyacetone phosphate from incubation mixtures.", "content": "On extraction of acyl and alkyl dihydroxyacetone phosphate from incubation mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371780"}
{"pmid": "4371781", "title": "Fully automated, all-enzymatic triglyceride method adapted to the GEMSAEC centrifugal analyzer, with use of an aqueous triolein standard.", "content": "Fully automated, all-enzymatic triglyceride method adapted to the GEMSAEC centrifugal analyzer, with use of an aqueous triolein standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371781"}
{"pmid": "4371782", "title": "Study of nucleolar vacuolation and RNA synthesis in embryonic root cells of Zea mays.", "content": "Study of nucleolar vacuolation and RNA synthesis in embryonic root cells of Zea mays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371782"}
{"pmid": "4371783", "title": "Epoxy-fiberglass adsorbent for concentrating viruses from large volumes of potable water.", "content": "Epoxy-fiberglass adsorbent for concentrating viruses from large volumes of potable water. A simple and compact virus-adsorbing unit for efficiently concentrating human enteric viruses from 100 gallons (about 380 liters) or more of potable water is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371783"}
{"pmid": "4371784", "title": "Prolyl hydroxylase.", "content": "Prolyl hydroxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371784"}
{"pmid": "4371785", "title": "Adenylate cyclase activity in rat adipocyte plasma membranes after adrenalectomy and administration of cortisone acetate. Effects of calcium ions and hormonal stimulations.", "content": "Adenylate cyclase activity in rat adipocyte plasma membranes after adrenalectomy and administration of cortisone acetate. Effects of calcium ions and hormonal stimulations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371785"}
{"pmid": "4371786", "title": "Acetylglutamate kinase: a feedback-sensitive enzyme of arginine biosynthesis in Neurospora.", "content": "Acetylglutamate kinase: a feedback-sensitive enzyme of arginine biosynthesis in Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371786"}
{"pmid": "4371787", "title": "Biosynthesis of collagen and elastin by chick embryo skin during maturation.", "content": "Biosynthesis of collagen and elastin by chick embryo skin during maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371787"}
{"pmid": "4371788", "title": "Biosynthesis of oligogalactosyl side chains of the cell envelope glycoprotein of Cryptococcus laurentii.", "content": "Biosynthesis of oligogalactosyl side chains of the cell envelope glycoprotein of Cryptococcus laurentii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371788"}
{"pmid": "4371789", "title": "Analysis of penicillic acid by gas-liquid chromatography.", "content": "Analysis of penicillic acid by gas-liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371789"}
{"pmid": "4371792", "title": "The Klippel-Trenaunay-Weber syndrome.", "content": "The Klippel-Trenaunay-Weber syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371792"}
{"pmid": "4371790", "title": "Analytical fractionation of homogenates from cultured rat embryo fibroblasts.", "content": "Analytical fractionation of homogenates from cultured rat embryo fibroblasts. Homogenates of cultured rat embryo fibroblasts have been assayed for acid phosphatase, N-acetyl-beta-glucosaminidase, cathepsin D, acid deoxyribonuclease, cytochrome oxidase, NADH cytochrome c reductase, 5'-nucleotidase, inosine diphosphatase, acid pyrophosphatase, neutral pyrophosphatase, esterase, catalase, cholesterol, and RNA. The validity of the assay conditions was checked. Neutral pyrophosphatase is a readily soluble enzyme. Acid hydrolases, except acid pyrophosphatase, are particle-bound enzymes, which exhibit a high degree of structural latency. They are activated and solubilized in a parallel fashion by mechanical treatments and tensio-active agents. Catalase is also particle-bound and latent; activating conditions stronger than those for hydrolases are required to activate the enzyme. Acid pyrophosphatase, 5'-nucleotidase and inosine diphosphatase are firmly particle-bound, but not latent; they are not easily solubilized. In differential and isopycnic centrifugation, the latent hydrolases, cytochrome oxidase and catalase dissociate largely from each other; this suggests the occurrence of lysosomes and peroxisome-like structures besides mitochondria. The distribution patterns of 5'-nucleotidase and cholesterol are largely similar; digitonin influences their equilibrium density to the same extent; these two constituents are thought to be related to the plasma membrane. Inosine diphosphatase and acid pyrophosphatase are also partially associated with the plasma membrane, although some part of these enzymic activities probably belongs to other structures. NADH cytochrome c reductase is associated partly with the endoplasmic reticulum, partly with mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371790"}
{"pmid": "4371793", "title": "The Mn2+-activated incorporation of inositol into molecular species of phosphatidylinositol in rat liver microsomes.", "content": "The Mn2+-activated incorporation of inositol into molecular species of phosphatidylinositol in rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371793"}
{"pmid": "4371803", "title": "Copper and zinc levels in peripheral nerve tissues of rats with experimental carbon-disulphide neuropathy.", "content": "Copper and zinc levels in peripheral nerve tissues of rats with experimental carbon-disulphide neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371803"}
{"pmid": "4371804", "title": "A study of the histological cell types of lung cancer in workers suffering from asbestosis in the United Kingdom.", "content": "A study of the histological cell types of lung cancer in workers suffering from asbestosis in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371804"}
{"pmid": "4371805", "title": "What a dream is.", "content": "What a dream is.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371805"}
{"pmid": "4371806", "title": "Relapsing polychondritis and eye disease.", "content": "Relapsing polychondritis and eye disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371806"}
{"pmid": "4371808", "title": "Imidazole catalysis of amino proton exchange in 2',3'-cyclic adenosine monophosphate. A general exchange mechanism.", "content": "Imidazole catalysis of amino proton exchange in 2',3'-cyclic adenosine monophosphate. A general exchange mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371808"}
{"pmid": "4371807", "title": "Focal dermal hypoplasia.", "content": "Focal dermal hypoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371807"}
{"pmid": "4371809", "title": "Physical and chemical properties of rabbit muscle phosphofructokinase cross-linked with dimethyl suberimidate.", "content": "Physical and chemical properties of rabbit muscle phosphofructokinase cross-linked with dimethyl suberimidate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371809"}
{"pmid": "4371810", "title": "A homogeneous, thermostable deoxythymidine kinase from Bacillus stearothermophilus.", "content": "A homogeneous, thermostable deoxythymidine kinase from Bacillus stearothermophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371810"}
{"pmid": "4371811", "title": "The phosphorylation of ribavirin by deoxyadenosine kinase from rat liver. Differentiation between adenosine and deoxyadenosine kinase.", "content": "The phosphorylation of ribavirin by deoxyadenosine kinase from rat liver. Differentiation between adenosine and deoxyadenosine kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371811"}
{"pmid": "4371812", "title": "Biosynthesis of cartilage procollagen. Influence of chain association and hydroxylation of prolyl residues on the folding of the polypeptides into the triple-helical conformation.", "content": "Biosynthesis of cartilage procollagen. Influence of chain association and hydroxylation of prolyl residues on the folding of the polypeptides into the triple-helical conformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371812"}
{"pmid": "4371813", "title": "Ferrous porphyrins in organic solvents. II. Optical spectra and paramagnetic susceptibilities.", "content": "Ferrous porphyrins in organic solvents. II. Optical spectra and paramagnetic susceptibilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371813"}
{"pmid": "4371814", "title": "Structure of the primary acid rearrangement product of reduced nicotinamide adenine dinucleotide (NADH).", "content": "Structure of the primary acid rearrangement product of reduced nicotinamide adenine dinucleotide (NADH).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371814"}
{"pmid": "4371815", "title": "Glyceraldehyde-3-phosphate dehydrogenase catalyzed hydration of the 5-6 double bond of reduced beta-nicotinamide adenine dinucleotide (betaNADH). Formation of beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide.", "content": "Glyceraldehyde-3-phosphate dehydrogenase catalyzed hydration of the 5-6 double bond of reduced beta-nicotinamide adenine dinucleotide (betaNADH). Formation of beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371815"}
{"pmid": "4371816", "title": "Topography of 16S RNA in 30S ribosomal subunits. Nucleotide sequences and location of sites of reaction with kethoxal.", "content": "Topography of 16S RNA in 30S ribosomal subunits. Nucleotide sequences and location of sites of reaction with kethoxal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371816"}
{"pmid": "4371817", "title": "Purification and characterization of two forms of geranyl transferase from Ricinus communis.", "content": "Purification and characterization of two forms of geranyl transferase from Ricinus communis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371817"}
{"pmid": "4371818", "title": "Trypsin-modified isoleucyl transfer ribonucleic acid synthetase with partial retention of activity.", "content": "Trypsin-modified isoleucyl transfer ribonucleic acid synthetase with partial retention of activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371818"}
{"pmid": "4371819", "title": "Structure of the major complex formed by interaction of phosphatidylcholine bilamellar vesicles and apolipoprotein-alanine (APO-C-III).", "content": "Structure of the major complex formed by interaction of phosphatidylcholine bilamellar vesicles and apolipoprotein-alanine (APO-C-III).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371819"}
{"pmid": "4371820", "title": "The dynamic structure of fatty acyl chains in a phospholipid bilayer measured by deuterium magnetic resonance.", "content": "The dynamic structure of fatty acyl chains in a phospholipid bilayer measured by deuterium magnetic resonance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371820"}
{"pmid": "4371821", "title": "The reactivity of conformationally modified cytochrome c.", "content": "The reactivity of conformationally modified cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371821"}
{"pmid": "4371822", "title": "Mechanism of the mutagenic action of hydroxylamine. VII. Functional activity and specificity of cytidine triphosphate modified with hydroxylamine and O-methylhydroxylamine.", "content": "Mechanism of the mutagenic action of hydroxylamine. VII. Functional activity and specificity of cytidine triphosphate modified with hydroxylamine and O-methylhydroxylamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371822"}
{"pmid": "4371823", "title": "Effects of temperature-induced phase changes in membranes on protein synthesis by bound ribosomes.", "content": "Effects of temperature-induced phase changes in membranes on protein synthesis by bound ribosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371823"}
{"pmid": "4371824", "title": "Ribosomal and soluble protein synthesis during a nutritional shift-up. Influence of cyclic AMP on beta-galactosidase activity.", "content": "Ribosomal and soluble protein synthesis during a nutritional shift-up. Influence of cyclic AMP on beta-galactosidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371824"}
{"pmid": "4371825", "title": "Steroid-protein interactions. XXX. A progesterone-binding protein in the uterine cytosol of the pregnant guinea pig.", "content": "Steroid-protein interactions. XXX. A progesterone-binding protein in the uterine cytosol of the pregnant guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371825"}
{"pmid": "4371826", "title": "Enzymatic repair of x-ray-damaged DNA. I. Labeling of the precursor of a malonaldehyde-like material in X-irradiated DNA and the enzymatic excision of labeled lesions.", "content": "Enzymatic repair of x-ray-damaged DNA. I. Labeling of the precursor of a malonaldehyde-like material in X-irradiated DNA and the enzymatic excision of labeled lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371826"}
{"pmid": "4371827", "title": "Low molecular weight DNA polymerase of rat ascites hepatoma cells.", "content": "Low molecular weight DNA polymerase of rat ascites hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371827"}
{"pmid": "4371828", "title": "Characterization of the 5'-terminus of murine leukemia virus RNA.", "content": "Characterization of the 5'-terminus of murine leukemia virus RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371828"}
{"pmid": "4371830", "title": "Effect of cyclic AMP on nucleoside metabolism. III. Effect on uridine incorporation in monkey (CV-1) cells.", "content": "Effect of cyclic AMP on nucleoside metabolism. III. Effect on uridine incorporation in monkey (CV-1) cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371830"}
{"pmid": "4371829", "title": "ESR evidence for the radiation-induced breakage of the sugar-phosphate bonds in nucleotides: single crystal of deoxycytidine 5'-monophosphate.", "content": "ESR evidence for the radiation-induced breakage of the sugar-phosphate bonds in nucleotides: single crystal of deoxycytidine 5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371829"}
{"pmid": "4371831", "title": "Purification of pig heart mitochondrial membranes. Enzymatic and morphological characterization as compared to microsomes.", "content": "Purification of pig heart mitochondrial membranes. Enzymatic and morphological characterization as compared to microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371831"}
{"pmid": "4371833", "title": "Chain ordering in liquid crystals. II. Structure of bilayer membranes.", "content": "Chain ordering in liquid crystals. II. Structure of bilayer membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371833"}
{"pmid": "4371832", "title": "Studies on Tetrahymena membranes: temperature-induced alterations in fatty acid composition of various membrane fractions in Tetrahymena pyriformis and its effect on membrane fluidity as inferred by spin-label study.", "content": "Studies on Tetrahymena membranes: temperature-induced alterations in fatty acid composition of various membrane fractions in Tetrahymena pyriformis and its effect on membrane fluidity as inferred by spin-label study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371832"}
{"pmid": "4371835", "title": "Some factors affecting the valinomycin-induced leak from liposomes.", "content": "Some factors affecting the valinomycin-induced leak from liposomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371835"}
{"pmid": "4371834", "title": "A plasma membrane fraction from bovine adrenal medulla: preparation, marker enzyme studies and phospholipid composition.", "content": "A plasma membrane fraction from bovine adrenal medulla: preparation, marker enzyme studies and phospholipid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371834"}
{"pmid": "4371836", "title": "The effect of phospholipase on the binding of asialoglycoproteins by rat liver plasma membranes.", "content": "The effect of phospholipase on the binding of asialoglycoproteins by rat liver plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371836"}
{"pmid": "4371837", "title": "Substrate-induced membrane potential changes in the perfused rat liver.", "content": "Substrate-induced membrane potential changes in the perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371837"}
{"pmid": "4371838", "title": "Biosynthetic pathways and turnover of individual biliary phosphatidylcholines during metabolism of (1,1-2H2)ethanol in the rat.", "content": "Biosynthetic pathways and turnover of individual biliary phosphatidylcholines during metabolism of (1,1-2H2)ethanol in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371838"}
{"pmid": "4371839", "title": "Biosynthesis of molecular species of phosphatidylcholines in bile, liver and plasma of rats given (1,1-2H2)ethanol.", "content": "Biosynthesis of molecular species of phosphatidylcholines in bile, liver and plasma of rats given (1,1-2H2)ethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371839"}
{"pmid": "4371840", "title": "Mono-acid diacylglycerols in human adipose tissue.", "content": "Mono-acid diacylglycerols in human adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371840"}
{"pmid": "4371841", "title": "Lipid components of two different regions of an intestinal epithelial cell membrane of mouse.", "content": "Lipid components of two different regions of an intestinal epithelial cell membrane of mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371841"}
{"pmid": "4371842", "title": "The kinetics of NAD-linked isocitrate dehydrogenase from calf heart.", "content": "The kinetics of NAD-linked isocitrate dehydrogenase from calf heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371842"}
{"pmid": "4371843", "title": "Protein kinases in Tetrahymena cilia. II. Partial purification and characterization of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases.", "content": "Protein kinases in Tetrahymena cilia. II. Partial purification and characterization of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371843"}
{"pmid": "4371844", "title": "Studies on manganese-substrate complexes of arginine kinase from Panulirus longipes.", "content": "Studies on manganese-substrate complexes of arginine kinase from Panulirus longipes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371844"}
{"pmid": "4371845", "title": "Effect of sulfhydryl reagents on the activity of histidinolphosphatase from Salmonella typhimurium and bakers' yeast.", "content": "Effect of sulfhydryl reagents on the activity of histidinolphosphatase from Salmonella typhimurium and bakers' yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371845"}
{"pmid": "4371847", "title": "Separation of multiple forms of cyclic nucleotide phosphodiesterases from rat brain by isoelectrofocusing.", "content": "Separation of multiple forms of cyclic nucleotide phosphodiesterases from rat brain by isoelectrofocusing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371847"}
{"pmid": "4371846", "title": "Cyclic nucleotide phosphodiesterase in silkworm: purification and properties.", "content": "Cyclic nucleotide phosphodiesterase in silkworm: purification and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371846"}
{"pmid": "4371848", "title": "Identification of the thiol residues involved in modifications of pig heart lipoamide dehydrogenase by cupric ion and by iodoacetamide.", "content": "Identification of the thiol residues involved in modifications of pig heart lipoamide dehydrogenase by cupric ion and by iodoacetamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371848"}
{"pmid": "4371849", "title": "Oxidation of NADH by melanin and melanoproteins.", "content": "Oxidation of NADH by melanin and melanoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371849"}
{"pmid": "4371850", "title": "Regulation of purine metabolism in Schizosaccharomyces pombe. IV. Variations in the stability and kinetic parameters of amidophosphoribosyltransferase depending on growth phase and growth conditions.", "content": "Regulation of purine metabolism in Schizosaccharomyces pombe. IV. Variations in the stability and kinetic parameters of amidophosphoribosyltransferase depending on growth phase and growth conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371850"}
{"pmid": "4371852", "title": "EPR studies of nitric oxide complexes of turnip and horse-radish peroxidases.", "content": "EPR studies of nitric oxide complexes of turnip and horse-radish peroxidases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371852"}
{"pmid": "4371851", "title": "A fluorescent probe for the coenzyme-induced structural changes in glyceraldehyde-3-phosphate dehydrogenase from rabbit muscle.", "content": "A fluorescent probe for the coenzyme-induced structural changes in glyceraldehyde-3-phosphate dehydrogenase from rabbit muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371851"}
{"pmid": "4371853", "title": "Binding of the estradiol receptor from calf uterus to the chromatin: active forms.", "content": "Binding of the estradiol receptor from calf uterus to the chromatin: active forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371853"}
{"pmid": "4371854", "title": "Tritium labeling of luteinizing hormone by reductive methylation.", "content": "Tritium labeling of luteinizing hormone by reductive methylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371854"}
{"pmid": "4371855", "title": "The apoproteins of various size classes of human chylous fluid lipoproteins.", "content": "The apoproteins of various size classes of human chylous fluid lipoproteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371855"}
{"pmid": "4371856", "title": "Magnetic susceptibility of lacquer tree laccase.", "content": "Magnetic susceptibility of lacquer tree laccase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371856"}
{"pmid": "4371858", "title": "Metabolism of phytane in rats.", "content": "Metabolism of phytane in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371858"}
{"pmid": "4371857", "title": "Multiple molecular forms of phosphoprotein phosphatase. II. Dissociation and activation of phosphorylase phosphatase from rabbit skeletal muscle.", "content": "Multiple molecular forms of phosphoprotein phosphatase. II. Dissociation and activation of phosphorylase phosphatase from rabbit skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371857"}
{"pmid": "4371859", "title": "The cleavage of the carbon--cobalt bond in vitamin B12 and coenzyme B12 by reduction with electrons in gamma-irradiated frozen solutions.", "content": "The cleavage of the carbon--cobalt bond in vitamin B12 and coenzyme B12 by reduction with electrons in gamma-irradiated frozen solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371859"}
{"pmid": "4371860", "title": "The pancreatic beta-cell recognition of insulin secretagogues. XIII. Effects of sulphydryl reagents on cyclic AMP.", "content": "The pancreatic beta-cell recognition of insulin secretagogues. XIII. Effects of sulphydryl reagents on cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371860"}
{"pmid": "4371861", "title": "Subcellular localization and some properties of the adenylate cyclase activity of the yeast, Saccharomyces cerevisiae.", "content": "Subcellular localization and some properties of the adenylate cyclase activity of the yeast, Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371861"}
{"pmid": "4371862", "title": "Cyclic AMP and thyroglobulin biosynthesis in the experimental rat thyroid tumor.", "content": "Cyclic AMP and thyroglobulin biosynthesis in the experimental rat thyroid tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371862"}
{"pmid": "4371863", "title": "The isolation and partial characterization of a glycoprotein isolated from human gastric aspirates and from extracts of gastric mucosae.", "content": "The isolation and partial characterization of a glycoprotein isolated from human gastric aspirates and from extracts of gastric mucosae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371863"}
{"pmid": "4371864", "title": "The effect of isoproterenol and its analogs upon adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate levels in mouse parotid gland in vivo. Relationship to the stimulation of DNA synthesis.", "content": "The effect of isoproterenol and its analogs upon adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate levels in mouse parotid gland in vivo. Relationship to the stimulation of DNA synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371864"}
{"pmid": "4371865", "title": "The actions of insulin and glucagon on glucose metabolism and on related enzyme activities in the isolated perfused rat liver.", "content": "The actions of insulin and glucagon on glucose metabolism and on related enzyme activities in the isolated perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371865"}
{"pmid": "4371867", "title": "Glycoprotein biosynthesis in liver mitochondria. II. Mitochondrial localization of mannosyltransferase.", "content": "Glycoprotein biosynthesis in liver mitochondria. II. Mitochondrial localization of mannosyltransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371867"}
{"pmid": "4371869", "title": "The effect of pressure on the phase diagram of mixed dipalmitoyl-dimyristoylphosphatidylcholine bilayers.", "content": "The effect of pressure on the phase diagram of mixed dipalmitoyl-dimyristoylphosphatidylcholine bilayers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371869"}
{"pmid": "4371866", "title": "Androgen receptors in rat ventral prostate microsomes.", "content": "Androgen receptors in rat ventral prostate microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371866"}
{"pmid": "4371868", "title": "Cycloheximide inhibition of hypoxanthine transport cultured cells.", "content": "Cycloheximide inhibition of hypoxanthine transport cultured cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371868"}
{"pmid": "4371870", "title": "Effect of several \"specific\" chemical reagents on the Na+, K+ and leakage currents in voltage-clamped single nodes of Ranvier.", "content": "Effect of several \"specific\" chemical reagents on the Na+, K+ and leakage currents in voltage-clamped single nodes of Ranvier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371870"}
{"pmid": "4371871", "title": "Effect of chemical modifiers of passive permeability on the conformation of spin-labeled erythrocyte membranes.", "content": "Effect of chemical modifiers of passive permeability on the conformation of spin-labeled erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371871"}
{"pmid": "4371872", "title": "Effect of theophylline and Na+ on methionine influx in Na+-depleted intestine.", "content": "Effect of theophylline and Na+ on methionine influx in Na+-depleted intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371872"}
{"pmid": "4371873", "title": "Temperature sensitivity of the assembly process of the enveloped bacteriophage phi6.", "content": "Temperature sensitivity of the assembly process of the enveloped bacteriophage phi6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371873"}
{"pmid": "4371875", "title": "The methylation of transfer RNA in Escherichia coli.", "content": "The methylation of transfer RNA in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371875"}
{"pmid": "4371874", "title": "Properties of the homogeneous main band DNA from the human genome.", "content": "Properties of the homogeneous main band DNA from the human genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371874"}
{"pmid": "4371884", "title": "Is there a first night effect? (a revisit).", "content": "Is there a first night effect? (a revisit).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371884"}
{"pmid": "4371883", "title": "Longitudinal study of the effects of lithium carbonate on the sleep of hospitalized depressed patients.", "content": "Longitudinal study of the effects of lithium carbonate on the sleep of hospitalized depressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371883"}
{"pmid": "4371885", "title": "Spontaneously recalled verbal material and its linguistic organization in relation to different stages of sleep.", "content": "Spontaneously recalled verbal material and its linguistic organization in relation to different stages of sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371885"}
{"pmid": "4371886", "title": "The intracellular phase of fat absorption.", "content": "The intracellular phase of fat absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371886"}
{"pmid": "4371887", "title": "Simplified radioimmunoassay of angiotensin II.", "content": "Simplified radioimmunoassay of angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371887"}
{"pmid": "4371888", "title": "Some hydrodynamic and optical properties of polyribonucleotides.", "content": "Some hydrodynamic and optical properties of polyribonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371888"}
{"pmid": "4371889", "title": "On site heterogeneity in sturgeon muscle GPDH: a kinetic approach.", "content": "On site heterogeneity in sturgeon muscle GPDH: a kinetic approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371889"}
{"pmid": "4371890", "title": "Nucleotide and serotonin metabolism in platelets with defective secondary aggregation.", "content": "Nucleotide and serotonin metabolism in platelets with defective secondary aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371890"}
{"pmid": "4371891", "title": "Criteria for the differentiation of lymphoid cell lines.", "content": "Criteria for the differentiation of lymphoid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371891"}
{"pmid": "4371893", "title": "Further observations on the virological studies on the epidemic of conjunctivitis in Calcutta.", "content": "Further observations on the virological studies on the epidemic of conjunctivitis in Calcutta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371893"}
{"pmid": "4371892", "title": "Isolation of virus from the urine, conjunctiva and throat of smallpox cases.", "content": "Isolation of virus from the urine, conjunctiva and throat of smallpox cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371892"}
{"pmid": "4371894", "title": "Role of acetylcholine in the mechanism of nervous autoregulation of the heart.", "content": "Role of acetylcholine in the mechanism of nervous autoregulation of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371894"}
{"pmid": "4371895", "title": "Role of the limbic structures in the mechanism of action of glucocorticoids and estrogens on hypothalamic control of pituitary adrenocorticotropic and gonadotropic functions.", "content": "Role of the limbic structures in the mechanism of action of glucocorticoids and estrogens on hypothalamic control of pituitary adrenocorticotropic and gonadotropic functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371895"}
{"pmid": "4371897", "title": "A rare case of hidradenoma papilliferum: report of a case and review of the literature.", "content": "A rare case of hidradenoma papilliferum: report of a case and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371897"}
{"pmid": "4371896", "title": "The mechanism of action of ACTH on the adrenal cortex.", "content": "The mechanism of action of ACTH on the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371896"}
{"pmid": "4371898", "title": "Vascular reactivity in spontaneously hypertensive normotensive and hypotensive rats.", "content": "Vascular reactivity in spontaneously hypertensive normotensive and hypotensive rats. 1 Three strains of rats spontaneously hypertensive (HRS), normotensive (NS) and hypotensive (HOS), were selected by repeated inbreeding.2 In order to explain the different blood pressure levels observed, we have studied their vascular reactivity to noradrenaline and angiotensin II. Experiments were performed in anaesthetized ganglion-blocked, vagotomized rats.3 The reactivity to noradrenaline was significantly higher in HRS than in NS and HOS rats.4 The reactivity to angiotensin II appeared identical in the three strains used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371898"}
{"pmid": "4371899", "title": "Effects on plasma and brain tryptophan in the rat of drugs and hormones that influence the concentration of unesterified fatty acid in the plasma.", "content": "Effects on plasma and brain tryptophan in the rat of drugs and hormones that influence the concentration of unesterified fatty acid in the plasma. 1 The effects on tryptophan distribution and metabolism of drugs altering plasma unesterified fatty acid (UFA) concentration were investigated in the rat.2 UFA and plasma free (i.e. ultrafilterable) tryptophan altered in the same direction.3 Catecholamines and L-DOPA increased both plasma UFA and free tryptophan. L-DOPA also increased brain tryptophan and 5-hydroxyindoleacetic acid (5-HIAA) but decreased brain 5-hydroxytryptamine (5-HT).4 Aminophylline increased plasma UFA and free tryptophan and also brain tryptophan, 5-HT and 5-HIAA. Food deprivation had qualitatively similar effects.5 Insulin decreased plasma UFA and free tryptophan in both fed and food-deprived rats. However, while in fed rats these changes were associated with small decreases of brain indoles, in food-deprived animals small increases occurred.6 Nicotinic acid had only small effects in fed rats but it opposed both the UFA and indole changes in food-deprived animals. Total plasma tryptophan increased in nicotinic acid treated, food-deprived rats.7 There was a tendency towards inverse relations between changes of plasma free and total tryptophan.8 The results suggest that drugs which influence plasma UFA through actions on cyclic AMP thereby alter the binding of tryptophan to plasma protein and that this leads to altered distribution and metabolism of tryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371899"}
{"pmid": "4371900", "title": "Mechanism of the pro-inflammatory activity of sympathomimetic amines in thermic oedema of the rat paw.", "content": "Mechanism of the pro-inflammatory activity of sympathomimetic amines in thermic oedema of the rat paw. 1 Thermic oedema induced by heating rat paws at 46.5 degrees C was potentiated by local injection of adrenaline, noradrenaline or high doses of isoprenaline. The pro-inflammatory effect of sympathomimetic amines was antagonized by phenoxybenzamine or phentolamine but not by propranolol.2 The subcutaneous space of heated rat paws was perfused with Tyrode solution and the perfusate collected and assayed for bradykinin, bradykininogen, kinin-forming activity and kininase activity. When adrenaline (0.5 mug/ml) was included in the perfusion fluid, kininase activity of the perfusate was increased by 76% and free bradykinin reduced by 46%.3 Increased vascular permeability induced by injection of bradykinin or kallikrein was reduced by adrenaline or noradrenaline, but isoprenaline had no significant effect.4 Pretreatment with soya bean trypsin inhibitor (SBTI) or heparin did not antagonize the pro-inflammatory effect of adrenaline or thermic oedema per se.5 Potentiation of thermic oedema similar to that induced by sympathomimetic amines was obtained by injecting paws with vasopressin prior to heating, or by applying a ligature to stop blood flow to the paw for the first 15 min of heating.6 Thermistor probes inserted beneath the paw skin showed that sympathomimetic amines increased the internal temperature of heated paws. This was significant, as small changes in temperature had a marked effect on the development of thermic oedema.7 It is suggested that sympathomimetic amines potentiate thermic oedema of rat paws heated at 46.5 degrees C by reducing blood flow to the paw, thereby causing a greater rise in paw temperature and consequently greater injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371900"}
{"pmid": "4371901", "title": "Effect of ethanol on the oxidative metabolism of tryptamine by rat liver homogenate.", "content": "Effect of ethanol on the oxidative metabolism of tryptamine by rat liver homogenate. 1 The effect of a wide range of ethanol concentrations (v/v) on indoleacetic acid (IAA) formation from the oxidative deamination of tryptamine was studied in vitro, in rat whole liver homogenate.2 IAA production was inhibited progressively by ethanol in concentrations between 0.01% to 0.2%, but the inhibition declined when the ethanol concentration was increased further to 6%.3 Ethanol-induced inhibition of IAA formation was only partially reversed by excess aldehyde dehydrogenase, whereas reductions in IAA formation were completely prevented by pyrazole or ethanol (6% and 10%) itself.4 Excess nicotinamide adenine dinucleotide failed to alter the inhibitory effect of ethanol and no evidence was obtained for inhibition of monoamine oxidase by ethanol or its metabolite, acetaldehyde.5 We conclude that ethanol indirectly inhibits IAA production as a result of oxidation of ethanol by alcohol dehydrogenase, during which the oxidative metabolism of tryptamine is shifted towards the reductive pathway, thus favouring the formation of tryptophol in place of IAA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371901"}
{"pmid": "4371902", "title": "Dose-response curves for angiotensin II and synthetic analogues in three types of smooth muscle: existence of different forms of receptor sites for angiotensin II.", "content": "Dose-response curves for angiotensin II and synthetic analogues in three types of smooth muscle: existence of different forms of receptor sites for angiotensin II. 1 The dose-response curves for angiotensin II and four analogues in rat colon and uterus, and in rabbit aorta, were obtained.2 The ED(50) values of angiotensin II as well as the ED(50)s and intrinsic activities of angiotensin analogues varied between the three organs.3 The interaction of two competitive antagonists with angiotensin II receptors was also examined. The K(I) values obtained with both antagonists on the uterus differed from the values on the other tissues.4 It is concluded that angiotensin II receptors may be different in the three organs examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371902"}
{"pmid": "4371903", "title": "Letter: B-lymphocytes as target cells for E.B. virus transformation.", "content": "Letter: B-lymphocytes as target cells for E.B. virus transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371903"}
{"pmid": "4371904", "title": "Editorial: Screening for hyperlipidaemia in childhood.", "content": "Editorial: Screening for hyperlipidaemia in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371904"}
{"pmid": "4371905", "title": "What could the G.P. treat at home--with proper support?", "content": "What could the G.P. treat at home--with proper support?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371905"}
{"pmid": "4371906", "title": "Letter: E.B. virus and treatment of lymphomas.", "content": "Letter: E.B. virus and treatment of lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371906"}
{"pmid": "4371907", "title": "Paradoxical sleep: prolonged augmentation following learning.", "content": "Paradoxical sleep: prolonged augmentation following learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371907"}
{"pmid": "4371912", "title": "Comparative measurements of the crystallinity of callus and compact bone by electron spin resonance spectrometry.", "content": "Comparative measurements of the crystallinity of callus and compact bone by electron spin resonance spectrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371912"}
{"pmid": "4371924", "title": "Evidence for the biosynthetic difference between isolated mitochondria and microsomes from guinea-pig and rat liver regarding lysophosphatidic acid, phosphatidic acid, CDP-diglyceride, phosphatidylglycerol, and cardiolipin.", "content": "Evidence for the biosynthetic difference between isolated mitochondria and microsomes from guinea-pig and rat liver regarding lysophosphatidic acid, phosphatidic acid, CDP-diglyceride, phosphatidylglycerol, and cardiolipin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371924"}
{"pmid": "4371923", "title": "Biosynthesis of spin-labelled lipids and their use in the study of biological membranes: isolation and characterization of membrane-bound spin-labelled sn-3-phosphatidic acid-2-3H prepared by enzymatic incorporation of spin-labelled stearic acid into sn-glycero-3-phosphate-2-3H.", "content": "Biosynthesis of spin-labelled lipids and their use in the study of biological membranes: isolation and characterization of membrane-bound spin-labelled sn-3-phosphatidic acid-2-3H prepared by enzymatic incorporation of spin-labelled stearic acid into sn-glycero-3-phosphate-2-3H.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371923"}
{"pmid": "4371925", "title": "Lipid and temperature dependence of membrane-bound ATPase activity of Acholeplasma laidlawii.", "content": "Lipid and temperature dependence of membrane-bound ATPase activity of Acholeplasma laidlawii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371925"}
{"pmid": "4371926", "title": "Isolation of dimethylallylpyrophosphate: umbelliferone dimethylally transferase from Ruta graveolens.", "content": "Isolation of dimethylallylpyrophosphate: umbelliferone dimethylally transferase from Ruta graveolens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371926"}
{"pmid": "4371927", "title": "Succinate dehydrogenases of Mucor rouxii and Penicillium duponti.", "content": "Succinate dehydrogenases of Mucor rouxii and Penicillium duponti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371927"}
{"pmid": "4371928", "title": "Localization of phosphate-independent glutaminase in the brush border of rat kidney cortex.", "content": "Localization of phosphate-independent glutaminase in the brush border of rat kidney cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371928"}
{"pmid": "4371930", "title": "Mutation test of 2,4,5-trichlorophenoxyacetic acid on Drosophila melanogaster.", "content": "Mutation test of 2,4,5-trichlorophenoxyacetic acid on Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371930"}
{"pmid": "4371929", "title": "Time differential in labelling of different monosaccharides into serum lipoproteins in rats.", "content": "Time differential in labelling of different monosaccharides into serum lipoproteins in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371929"}
{"pmid": "4371931", "title": "Mixed tumor of the nasal septum.", "content": "Mixed tumor of the nasal septum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371931"}
{"pmid": "4371932", "title": "Regulation of pancreatic acinar function: effects of cyclic AMP, dibutyryl cyclic AMP, and theophylline in vitro.", "content": "Regulation of pancreatic acinar function: effects of cyclic AMP, dibutyryl cyclic AMP, and theophylline in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371932"}
{"pmid": "4371933", "title": "Intestinal vasoconstriction following diuretic-induced volume depletion: role of angiotensin and vasopressin.", "content": "Intestinal vasoconstriction following diuretic-induced volume depletion: role of angiotensin and vasopressin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371933"}
{"pmid": "4371935", "title": "The effect of intravenous infusions of angiotensin and noradrenaline on systolic blood pressure and critical opening pressure of tail vessels in conscious rats.", "content": "The effect of intravenous infusions of angiotensin and noradrenaline on systolic blood pressure and critical opening pressure of tail vessels in conscious rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371935"}
{"pmid": "4371934", "title": "Stimulation of nerve fiber growth from cultured sympathetic explants.", "content": "Stimulation of nerve fiber growth from cultured sympathetic explants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371934"}
{"pmid": "4371936", "title": "Dantrolene sodium: effects on crustacean muscle.", "content": "Dantrolene sodium: effects on crustacean muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371936"}
{"pmid": "4371937", "title": "Negative cardiac inotropic effects of calcium ion and of N-2-hydroxyethylpiperazine-N' -2-ethanesulfonic acid (HEPES) buffer at normal and low sodium concentration.", "content": "Negative cardiac inotropic effects of calcium ion and of N-2-hydroxyethylpiperazine-N' -2-ethanesulfonic acid (HEPES) buffer at normal and low sodium concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371937"}
{"pmid": "4371938", "title": "Catecholamine binding and the turnover number of adenylate cyclase.", "content": "Catecholamine binding and the turnover number of adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371938"}
{"pmid": "4371939", "title": "Surgical treatment of Crohn's disease.", "content": "Surgical treatment of Crohn's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371939"}
{"pmid": "4371941", "title": "Criteria for the post-hospital adjustment of mental patients in sheltered settings.", "content": "Criteria for the post-hospital adjustment of mental patients in sheltered settings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371941"}
{"pmid": "4371942", "title": "A quantitative ultrastructural study of the pleomorphic adenoma (mixed tumor) of human minor salivary glands.", "content": "A quantitative ultrastructural study of the pleomorphic adenoma (mixed tumor) of human minor salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371942"}
{"pmid": "4371940", "title": "Pseudomembranous colitis associated with antibiotic therapy - an emerging entity.", "content": "Pseudomembranous colitis associated with antibiotic therapy - an emerging entity. Two cases of pseudomembranous colitis are presented. The first patient had been treated with novobiocin-tetracycline and penicillin, and two weeks later developed severe fulminating diarrhea with ascites and bilateral pleural effusions which did not respond to intravenous ACTH. Subsequently she underwent subtotal colectomy and made a rapid and complete recovery. The second patient developed severe diarrhea two weeks after a 10-day course of clindamycin. She was treated with intravenous ACTH, oral Lactobacillus and a fecal enema and made a complete recovery.These cases reconfirm the importance of antibiotics as etiologic agents in this disease. They also stress the classic sigmoidoscopic and histologic findings that should facilitate prompt and rapid diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371940"}
{"pmid": "4371943", "title": "Localized fibrous tumors of pleura: a light and electron microscopic study.", "content": "Localized fibrous tumors of pleura: a light and electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371943"}
{"pmid": "4371944", "title": "Cell kinetic studies in patients with small cell carcinoma of the lung.", "content": "Cell kinetic studies in patients with small cell carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371944"}
{"pmid": "4371945", "title": "Angiolymphoid hyperplasia with eosinophilia in the skin.", "content": "Angiolymphoid hyperplasia with eosinophilia in the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371945"}
{"pmid": "4371946", "title": "Urinary cholesterol--VI. Its excretion in women with inoperable inflammatory carcinoma of the breast.", "content": "Urinary cholesterol--VI. Its excretion in women with inoperable inflammatory carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371946"}
{"pmid": "4371947", "title": "Concurrence of carotid body tumor and pheochromocytoma.", "content": "Concurrence of carotid body tumor and pheochromocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371947"}
{"pmid": "4371950", "title": "Half-life of N-acetylneuraminic acid in plasma membranes of rat liver and Morris hepatoma 7777.", "content": "Half-life of N-acetylneuraminic acid in plasma membranes of rat liver and Morris hepatoma 7777.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371950"}
{"pmid": "4371951", "title": "A difference between B10.D2-n and B10.D2-o strains of mice in rates of irradiation-induced leukemogenesis.", "content": "A difference between B10.D2-n and B10.D2-o strains of mice in rates of irradiation-induced leukemogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371951"}
{"pmid": "4371952", "title": "Estrogen receptor content and hormone-responsive growth of mouse mammary tumors.", "content": "Estrogen receptor content and hormone-responsive growth of mouse mammary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371952"}
{"pmid": "4371953", "title": "Dietary effects on stearyl coenzyme A desaturase in Morris hepatomas.", "content": "Dietary effects on stearyl coenzyme A desaturase in Morris hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371953"}
{"pmid": "4371954", "title": "An ultrastructural study of C-type virion assembly in mouse cells.", "content": "An ultrastructural study of C-type virion assembly in mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371954"}
{"pmid": "4371948", "title": "Comparison of daunorubicin (NSC-83142) with adriamycin (NSC-123127) in the treatment of late-stage childhood solid tumors.", "content": "Comparison of daunorubicin (NSC-83142) with adriamycin (NSC-123127) in the treatment of late-stage childhood solid tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371948"}
{"pmid": "4371955", "title": "Two forms of repair in the DNA of human cells damaged by chemical carcinogens and mutagens.", "content": "Two forms of repair in the DNA of human cells damaged by chemical carcinogens and mutagens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371955"}
{"pmid": "4371956", "title": "Further investigation of a variant of the placental alkaline phosphatase in human hepatic carcinoma.", "content": "Further investigation of a variant of the placental alkaline phosphatase in human hepatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371956"}
{"pmid": "4371949", "title": "Evaluation of intravenous allopurinol (NSC-1390) in pediatric neoplasia.", "content": "Evaluation of intravenous allopurinol (NSC-1390) in pediatric neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371949"}
{"pmid": "4371958", "title": "Demonstration of glucose 6-phosphatase activity in the oval cells of rat liver and the significance of the oval cells in azo dye carcinogenesis.", "content": "Demonstration of glucose 6-phosphatase activity in the oval cells of rat liver and the significance of the oval cells in azo dye carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371958"}
{"pmid": "4371957", "title": "Tumor induction in the progeny of mice receiving 4-nitroquinoline 1-oxide and N-methyl-N-nitrosourethan during pregnancy or lactation.", "content": "Tumor induction in the progeny of mice receiving 4-nitroquinoline 1-oxide and N-methyl-N-nitrosourethan during pregnancy or lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371957"}
{"pmid": "4371959", "title": "Alteration of tumor response in rat liver by carbon tetrachloride.", "content": "Alteration of tumor response in rat liver by carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371959"}
{"pmid": "4371960", "title": "The effect of benzo(alpha)pyrene on the basal and isoproterenol-stimulated levels of cyclic adenosine 3',5'-monophosphate in mouse epidermis.", "content": "The effect of benzo(alpha)pyrene on the basal and isoproterenol-stimulated levels of cyclic adenosine 3',5'-monophosphate in mouse epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371960"}
{"pmid": "4371961", "title": "Incorporation of precursors and inhibitors of nucleic acid synthesis into hepatomas and liver of the rat.", "content": "Incorporation of precursors and inhibitors of nucleic acid synthesis into hepatomas and liver of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371961"}
{"pmid": "4371962", "title": "A leukemic lymphoproliferative diseases in A-J mice following inoculation with blood from patients with acute infectious hepatitis.", "content": "A leukemic lymphoproliferative diseases in A-J mice following inoculation with blood from patients with acute infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371962"}
{"pmid": "4371963", "title": "Phorbol-12-myristate-13-acetate effect on cyclic adenosine 3',5'-monophosphate levels in mouse skin and inhibition of phorbol-myristate-acetate-promoted tumorigenesis by theophylline.", "content": "Phorbol-12-myristate-13-acetate effect on cyclic adenosine 3',5'-monophosphate levels in mouse skin and inhibition of phorbol-myristate-acetate-promoted tumorigenesis by theophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371963"}
{"pmid": "4371964", "title": "In vitro growth of an attenuated mouse leukemia virus.", "content": "In vitro growth of an attenuated mouse leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371964"}
{"pmid": "4371965", "title": "The possible correlation of growth rate and expression of transformation with temperature-dependent modification in high-molecular-weight membrane glycoproteins in mammalian cells transformed by a wild-type and by a thermosensitive mutant of avian sarcoma virus.", "content": "The possible correlation of growth rate and expression of transformation with temperature-dependent modification in high-molecular-weight membrane glycoproteins in mammalian cells transformed by a wild-type and by a thermosensitive mutant of avian sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371965"}
{"pmid": "4371967", "title": "Enhancement of simian virus 40 transformation and integration by 4-nitroquinoline 1-oxide.", "content": "Enhancement of simian virus 40 transformation and integration by 4-nitroquinoline 1-oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371967"}
{"pmid": "4371966", "title": "In vivo inhibition of tumor growth by cyclic adenosine 3',5'-monophosphate derivatives.", "content": "In vivo inhibition of tumor growth by cyclic adenosine 3',5'-monophosphate derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371966"}
{"pmid": "4371968", "title": "Cation preferences for poly(rC)-oligo(dG)-directed DNA synthesis by RNA tumor viruses and human milk particulates.", "content": "Cation preferences for poly(rC)-oligo(dG)-directed DNA synthesis by RNA tumor viruses and human milk particulates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371968"}
{"pmid": "4371969", "title": "Periodate oxidation of L-iduronic acid residues in dermatan sulphate.", "content": "Periodate oxidation of L-iduronic acid residues in dermatan sulphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371969"}
{"pmid": "4371970", "title": "Alkaline and smith degradation of oxidized dermatan sulphate-chondroitin sulphate copolymers.", "content": "Alkaline and smith degradation of oxidized dermatan sulphate-chondroitin sulphate copolymers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371970"}
{"pmid": "4371971", "title": "Periodate oxidation, acid hydrolysis, and structure-activity relationships of human-pituitary, follicle-stimulating hormone and human chorionic gonadotrophin.", "content": "Periodate oxidation, acid hydrolysis, and structure-activity relationships of human-pituitary, follicle-stimulating hormone and human chorionic gonadotrophin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371971"}
{"pmid": "4371972", "title": "Chemical synthesis of P1-2-acetamido-2-deoxy-alpha-D-glucopyranosyl P2-dolichyl pyrophosphate.", "content": "Chemical synthesis of P1-2-acetamido-2-deoxy-alpha-D-glucopyranosyl P2-dolichyl pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371972"}
{"pmid": "4371973", "title": "The attachment of poly(ribitol phosphate) to lipoteichoic acid carrier.", "content": "The attachment of poly(ribitol phosphate) to lipoteichoic acid carrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371973"}
{"pmid": "4371974", "title": "A micromethod for the determination of 5-(adenosine 5'-pyrophosphoryl)-D-ribose (adenosine diphosphoribose-(5)) in biological extracts.", "content": "A micromethod for the determination of 5-(adenosine 5'-pyrophosphoryl)-D-ribose (adenosine diphosphoribose-(5)) in biological extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371974"}
{"pmid": "4371975", "title": "Immunochemical studies on the specificity of soybean agglutinin.", "content": "Immunochemical studies on the specificity of soybean agglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371975"}
{"pmid": "4371976", "title": "Fine structural localization of nucleoside triphosphatase and acid phosphatase activity in Trichomonas vaginalis Donné.", "content": "Fine structural localization of nucleoside triphosphatase and acid phosphatase activity in Trichomonas vaginalis Donné.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371976"}
{"pmid": "4371978", "title": "Cephalopod integument: the ultrastructure of Kölliker's organs and their relationship to setae.", "content": "Cephalopod integument: the ultrastructure of Kölliker's organs and their relationship to setae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371978"}
{"pmid": "4371977", "title": "Investigations on turnover of adrenocortical mitochondria. II. Effect of chronic treatment with ACTH on the 3H-thymidine incorporation into rat zona fasciculata mitochondria.", "content": "Investigations on turnover of adrenocortical mitochondria. II. Effect of chronic treatment with ACTH on the 3H-thymidine incorporation into rat zona fasciculata mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371977"}
{"pmid": "4371979", "title": "Freeze-fracture studies on the cockroach hemocyte membrane complex: symmetric and asymmetric membrane particle distributions.", "content": "Freeze-fracture studies on the cockroach hemocyte membrane complex: symmetric and asymmetric membrane particle distributions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371979"}
{"pmid": "4371980", "title": "Ultrastructural and cytochemical localization of the storage sites of monoamines in the paraventricular organ of Xenopus laevis tadpoles.", "content": "Ultrastructural and cytochemical localization of the storage sites of monoamines in the paraventricular organ of Xenopus laevis tadpoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371980"}
{"pmid": "4371981", "title": "Pigment movements in fish melanophores: morphological and physiolgical studies. IV. The effect of cyclic adenosine monophosphate on normal and vinblastine treated melanophores.", "content": "Pigment movements in fish melanophores: morphological and physiolgical studies. IV. The effect of cyclic adenosine monophosphate on normal and vinblastine treated melanophores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371981"}
{"pmid": "4371982", "title": "Studies on the juxtaglomerular apparatus. III. Quantitative morphology after treatment with deoxycorticosterone (DOC).", "content": "Studies on the juxtaglomerular apparatus. III. Quantitative morphology after treatment with deoxycorticosterone (DOC).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371982"}
{"pmid": "4371984", "title": "Metabolism of cyclic adenosine 3':5'-monophosphate in somatic cell hybrids.", "content": "Metabolism of cyclic adenosine 3':5'-monophosphate in somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371984"}
{"pmid": "4371983", "title": "The release of secretory products from the corticotrophic cells of Salmo gairdneri in vitro.", "content": "The release of secretory products from the corticotrophic cells of Salmo gairdneri in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371983"}
{"pmid": "4371986", "title": "Nuclear protein changes during the nitrosamine-induced carcinogenesis of rat liver.", "content": "Nuclear protein changes during the nitrosamine-induced carcinogenesis of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371986"}
{"pmid": "4371987", "title": "Studies on viomycin. VII. Oxidative modifications of viomycin.", "content": "Studies on viomycin. VII. Oxidative modifications of viomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371987"}
{"pmid": "4371989", "title": "Studies on peptides. XLVI. Synthesis of human type corticotropin-like intermediate lobe peptide (CLIP).", "content": "Studies on peptides. XLVI. Synthesis of human type corticotropin-like intermediate lobe peptide (CLIP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371989"}
{"pmid": "4371988", "title": "Studies on peptides. XLV. Synthesis of the bovine type corticotropin-like intermediate lobe peptide (CLIP).", "content": "Studies on peptides. XLV. Synthesis of the bovine type corticotropin-like intermediate lobe peptide (CLIP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371988"}
{"pmid": "4371990", "title": "Synthesis of D,L-erythro-sphingomyelins.", "content": "Synthesis of D,L-erythro-sphingomyelins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371990"}
{"pmid": "4371992", "title": "Vascular effects of procaine amide in the dog. Predominance of the inhibitory effect on ganglionic transmission.", "content": "Vascular effects of procaine amide in the dog. Predominance of the inhibitory effect on ganglionic transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371992"}
{"pmid": "4371993", "title": "Characteristics of hypertension in the black population.", "content": "Characteristics of hypertension in the black population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371993"}
{"pmid": "4371994", "title": "Adolescent hypertension. II. Characteristics and response to treatment.", "content": "Adolescent hypertension. II. Characteristics and response to treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371994"}
{"pmid": "4371995", "title": "Altered sedimentation behavior and ultrastructure of platelets in hyperlipidemia.", "content": "Altered sedimentation behavior and ultrastructure of platelets in hyperlipidemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371995"}
{"pmid": "4371997", "title": "Transport of beta-carotene in serum of individuals with carotenemia.", "content": "Transport of beta-carotene in serum of individuals with carotenemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371997"}
{"pmid": "4371996", "title": "Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino penicillanic acid and related substances.", "content": "Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino penicillanic acid and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371996"}
{"pmid": "4371998", "title": "Development and standardization of radioimmunoassays for prostaglandins E, F, and A.", "content": "Development and standardization of radioimmunoassays for prostaglandins E, F, and A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371998"}
{"pmid": "4371999", "title": "Isozymes of human alpha-L-fucosidase detectable by starch gel electrophoresis.", "content": "Isozymes of human alpha-L-fucosidase detectable by starch gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4371999"}
{"pmid": "4372000", "title": "Further characterization of the serum pre-alpha-lipoprotein.", "content": "Further characterization of the serum pre-alpha-lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372000"}
{"pmid": "4372001", "title": "Control of plasma aldosterone in supine anephric man.", "content": "Control of plasma aldosterone in supine anephric man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372001"}
{"pmid": "4372002", "title": "Evidence for an underlying adrenocortical abnormality in hirsute women.", "content": "Evidence for an underlying adrenocortical abnormality in hirsute women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372002"}
{"pmid": "4372010", "title": "A syndrome of polydactyly-syndactyly and triphalangeal thumbs in three generations.", "content": "A syndrome of polydactyly-syndactyly and triphalangeal thumbs in three generations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372010"}
{"pmid": "4372011", "title": "Lp(a) lipoprotein and pre-beta1-lipoprotein in patients with coronary heart disease.", "content": "Lp(a) lipoprotein and pre-beta1-lipoprotein in patients with coronary heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372011"}
{"pmid": "4372013", "title": "Aldosterone and its regulation during diuresis in patients with gross congestive heart failure.", "content": "Aldosterone and its regulation during diuresis in patients with gross congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372013"}
{"pmid": "4372014", "title": "Changes in the fatty acid composition of plasma lipoproteins during administration of Intralipid to a patient with essential fatty acid deficiency.", "content": "Changes in the fatty acid composition of plasma lipoproteins during administration of Intralipid to a patient with essential fatty acid deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372014"}
{"pmid": "4372017", "title": "Leishmania donovani and L. mexicana: production of the excretion factor.", "content": "Leishmania donovani and L. mexicana: production of the excretion factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372017"}
{"pmid": "4372016", "title": "Composition of very low density lipoproteins from cholesterol fed animals.", "content": "Composition of very low density lipoproteins from cholesterol fed animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372016"}
{"pmid": "4372018", "title": "Chymotrypsins.", "content": "Chymotrypsins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372018"}
{"pmid": "4372019", "title": "Eggshell calcification with systemic sarcoidosis.", "content": "Eggshell calcification with systemic sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372019"}
{"pmid": "4372020", "title": "Granular cell myoblastoma of the bronchus: a new case, 12-year followup report, and review of the literature.", "content": "Granular cell myoblastoma of the bronchus: a new case, 12-year followup report, and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372020"}
{"pmid": "4372030", "title": "Uptake of exogenous 3H-1,2-testosterone in the hypothalamus, endocrine glands and sex-accessory organs in neonatally castrated and androgenized male rats.", "content": "Uptake of exogenous 3H-1,2-testosterone in the hypothalamus, endocrine glands and sex-accessory organs in neonatally castrated and androgenized male rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372030"}
{"pmid": "4372031", "title": "Correlation between the activities of enzymes involved in glucose oxidation in corpus luteum and the concentration of sex steroids in systemic plasma during the reproductive cycle of the guinea pig.", "content": "Correlation between the activities of enzymes involved in glucose oxidation in corpus luteum and the concentration of sex steroids in systemic plasma during the reproductive cycle of the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372031"}
{"pmid": "4372032", "title": "Ontogeny of rat hepatic glucocorticoid receptors.", "content": "Ontogeny of rat hepatic glucocorticoid receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372032"}
{"pmid": "4372033", "title": "Preparation of biologically active 125I-TSH.", "content": "Preparation of biologically active 125I-TSH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372033"}
{"pmid": "4372034", "title": "Functional and morphological observations on rat adrenal zona glomerulosa cells in monolayer culture.", "content": "Functional and morphological observations on rat adrenal zona glomerulosa cells in monolayer culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372034"}
{"pmid": "4372035", "title": "The effects of hypothyroidism and 2,4-dinitrophenol on growth hormone synthesis.", "content": "The effects of hypothyroidism and 2,4-dinitrophenol on growth hormone synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372035"}
{"pmid": "4372036", "title": "Progesterone \"receptor\" in human endometrium.", "content": "Progesterone \"receptor\" in human endometrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372036"}
{"pmid": "4372037", "title": "Maternal and fetal plasma progesterone, cortisol, testosterone and 17beta-estradiol in preparturient sheep: response to fetal ACTH infusion.", "content": "Maternal and fetal plasma progesterone, cortisol, testosterone and 17beta-estradiol in preparturient sheep: response to fetal ACTH infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372037"}
{"pmid": "4372038", "title": "Interaction of lithium with vasopressin-sensitive cyclic AMP system of human renal medulla.", "content": "Interaction of lithium with vasopressin-sensitive cyclic AMP system of human renal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372038"}
{"pmid": "4372039", "title": "In vitro testosterone biosynthesis in the human fetal testis. II. Stimulation by cyclic AMP and human chorionic gonadotropin (hCG).", "content": "In vitro testosterone biosynthesis in the human fetal testis. II. Stimulation by cyclic AMP and human chorionic gonadotropin (hCG).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372039"}
{"pmid": "4372040", "title": "5Alpha-reduction and binding of testosterone in androgen-dependent and -independent mouse mammary tumors.", "content": "5Alpha-reduction and binding of testosterone in androgen-dependent and -independent mouse mammary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372040"}
{"pmid": "4372041", "title": "Chicken insulin: radioimmunological characterization and enhanced activity in rat fat cells and liver plasma membranes.", "content": "Chicken insulin: radioimmunological characterization and enhanced activity in rat fat cells and liver plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372041"}
{"pmid": "4372042", "title": "Inhibitory and facilitatory hypothalamic areas mediating ACTH release in the cat.", "content": "Inhibitory and facilitatory hypothalamic areas mediating ACTH release in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372042"}
{"pmid": "4372043", "title": "Stimulation of angiotensinogen release by hemodilution in the dog.", "content": "Stimulation of angiotensinogen release by hemodilution in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372043"}
{"pmid": "4372044", "title": "Multiple sclerosis: reticulum cell sarcoma of the nervous system in a patient treated with immunosuppressive drugs.", "content": "Multiple sclerosis: reticulum cell sarcoma of the nervous system in a patient treated with immunosuppressive drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372044"}
{"pmid": "4372046", "title": "Changes in cell mediated immune functions by growing tumor.", "content": "Changes in cell mediated immune functions by growing tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372046"}
{"pmid": "4372045", "title": "Chromosome studies on 14 near-diploid carcinomas of the ovary.", "content": "Chromosome studies on 14 near-diploid carcinomas of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372045"}
{"pmid": "4372047", "title": "Interferon production by leukocytes cultures from neoplastic patients.", "content": "Interferon production by leukocytes cultures from neoplastic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372047"}
{"pmid": "4372048", "title": "Antibiotic combinations of gram-negative infections in patients with cancer.", "content": "Antibiotic combinations of gram-negative infections in patients with cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372048"}
{"pmid": "4372049", "title": "Empirical antibiotic therapy in febrile patients with neutropenia and malignant disease.", "content": "Empirical antibiotic therapy in febrile patients with neutropenia and malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372049"}
{"pmid": "4372050", "title": "Advances in the management of Pseudomonas aeruginosa infections in cancer patients.", "content": "Advances in the management of Pseudomonas aeruginosa infections in cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372050"}
{"pmid": "4372051", "title": "Pseudomonas septicemia: incidence, epidemiology, prevention and therapy in patients with advanced cancer.", "content": "Pseudomonas septicemia: incidence, epidemiology, prevention and therapy in patients with advanced cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372051"}
{"pmid": "4372052", "title": "Immune response to adenovirus 12-induced tumour antigens, as measured in vitro by the macrophage migration inhibition test.", "content": "Immune response to adenovirus 12-induced tumour antigens, as measured in vitro by the macrophage migration inhibition test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372052"}
{"pmid": "4372053", "title": "In vivo effect of adenosine 3', 5'-monophosphate on Ehrlich ascites tumour cells.", "content": "In vivo effect of adenosine 3', 5'-monophosphate on Ehrlich ascites tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372053"}
{"pmid": "4372054", "title": "Estrogen receptors in human breast cancer.", "content": "Estrogen receptors in human breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372054"}
{"pmid": "4372055", "title": "Specific estrogen receptor of the DMBA-induced mammary carcinoma of the rat and its estrogen-requiring molecular transformation.", "content": "Specific estrogen receptor of the DMBA-induced mammary carcinoma of the rat and its estrogen-requiring molecular transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372055"}
{"pmid": "4372056", "title": "Interaction of activated estradiol-receptor complex and chromatin in isolated uterine nuclei.", "content": "Interaction of activated estradiol-receptor complex and chromatin in isolated uterine nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372056"}
{"pmid": "4372059", "title": "Interaction of vasopressins and linear N-terminal ACTH fragments in the induction of natriuresis.", "content": "Interaction of vasopressins and linear N-terminal ACTH fragments in the induction of natriuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372059"}
{"pmid": "4372058", "title": "Isolation of a tridecapeptide from Natriuretic fractions of bovine posterior pituitary.", "content": "Isolation of a tridecapeptide from Natriuretic fractions of bovine posterior pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372058"}
{"pmid": "4372057", "title": "Adrenal secretion of estrogens, glucocorticosteroids and mineralocorticosteroids in the dog.", "content": "Adrenal secretion of estrogens, glucocorticosteroids and mineralocorticosteroids in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372057"}
{"pmid": "4372060", "title": "Selective activation of mouse T and B lymphocytes by periodate, galactose oxidase and soybean agglutinin.", "content": "Selective activation of mouse T and B lymphocytes by periodate, galactose oxidase and soybean agglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372060"}
{"pmid": "4372061", "title": "The anti-virus activity of double-stranded RNA in the presence of antibody to double-stranded RNA.", "content": "The anti-virus activity of double-stranded RNA in the presence of antibody to double-stranded RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372061"}
{"pmid": "4372062", "title": "The influence of volume loading on the inotropic effect of Ro 7-2956.", "content": "The influence of volume loading on the inotropic effect of Ro 7-2956.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372062"}
{"pmid": "4372063", "title": "Antidiuretic hormone and renin in rats with diabetes insipidus.", "content": "Antidiuretic hormone and renin in rats with diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372063"}
{"pmid": "4372064", "title": "Cold potentiation of neuromuscular transmission in the avian biventer cervicis muscle.", "content": "Cold potentiation of neuromuscular transmission in the avian biventer cervicis muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372064"}
{"pmid": "4372066", "title": "Effects of droperidol on neuromuscular transmission and muscle membrane.", "content": "Effects of droperidol on neuromuscular transmission and muscle membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372066"}
{"pmid": "4372065", "title": "Release of prostaglandins from the rabbit renal medulla.", "content": "Release of prostaglandins from the rabbit renal medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372065"}
{"pmid": "4372068", "title": "Antibody-induced redistribution of normal and tumor associated surface antigens.", "content": "Antibody-induced redistribution of normal and tumor associated surface antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372068"}
{"pmid": "4372069", "title": "Rapid isolation of nucleoli from detergent purified nuclei of various tumor and tissue culture cells.", "content": "Rapid isolation of nucleoli from detergent purified nuclei of various tumor and tissue culture cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372069"}
{"pmid": "4372071", "title": "Isolation of temperature-sensitive mutants from murine leukemic cells (L5178Y).", "content": "Isolation of temperature-sensitive mutants from murine leukemic cells (L5178Y).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372071"}
{"pmid": "4372070", "title": "Isolation of Kupffer cell lysosomes, with observations on their chemical and enzymic composition.", "content": "Isolation of Kupffer cell lysosomes, with observations on their chemical and enzymic composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372070"}
{"pmid": "4372073", "title": "Influence of cell cycle and cell movement on the distribution of intramembranous particles in contact-inhibited and transformed cells.", "content": "Influence of cell cycle and cell movement on the distribution of intramembranous particles in contact-inhibited and transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372073"}
{"pmid": "4372072", "title": "In vitro phosphorylation of chicken erythrocyte histone by various protein kinases: absence of phosphorylation from F1 histone.", "content": "In vitro phosphorylation of chicken erythrocyte histone by various protein kinases: absence of phosphorylation from F1 histone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372072"}
{"pmid": "4372074", "title": "Proteases as mitogens. The Effect of trypsin and pronase on mouse and human lymphocytes.", "content": "Proteases as mitogens. The Effect of trypsin and pronase on mouse and human lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372074"}
{"pmid": "4372075", "title": "Complementation in hybrid cells derived from mutagen-induced mouse clones deficient in hypoxanthine-guanine phosphoribosyl-transferase activity.", "content": "Complementation in hybrid cells derived from mutagen-induced mouse clones deficient in hypoxanthine-guanine phosphoribosyl-transferase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372075"}
{"pmid": "4372076", "title": "Introduction of nuclei and micronuclei into cells and enucleated cytoplasms by Sendai virus induced fusion.", "content": "Introduction of nuclei and micronuclei into cells and enucleated cytoplasms by Sendai virus induced fusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372076"}
{"pmid": "4372077", "title": "Relation of activation of neurones in the pons and medulla to brain-stimulation reward.", "content": "Relation of activation of neurones in the pons and medulla to brain-stimulation reward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372077"}
{"pmid": "4372078", "title": "Cerebellar Purkynĕ cell responses to inputs from sensorimotor cortex.", "content": "Cerebellar Purkynĕ cell responses to inputs from sensorimotor cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372078"}
{"pmid": "4372080", "title": "Schistosoma mansoni: penetration apparatus and epidermis of the miracidium.", "content": "Schistosoma mansoni: penetration apparatus and epidermis of the miracidium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372080"}
{"pmid": "4372079", "title": "Somatotopically organized inputs from fore- and hindlimb areas of sensorimotor cortex to cerebellar Purkynĕ cells.", "content": "Somatotopically organized inputs from fore- and hindlimb areas of sensorimotor cortex to cerebellar Purkynĕ cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372079"}
{"pmid": "4372081", "title": "Effect of a catatoxic steroid pregnenolone-16alpha-carbonitrile, on rat liver microsomal subfractions.", "content": "Effect of a catatoxic steroid pregnenolone-16alpha-carbonitrile, on rat liver microsomal subfractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372081"}
{"pmid": "4372083", "title": "Isolation of rat liver cells containing concanavalin-A receptor sites.", "content": "Isolation of rat liver cells containing concanavalin-A receptor sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372083"}
{"pmid": "4372082", "title": "A comparative study of SV40-transformed fibroblast plasma membrane proteins labelled by enzymatic iodination or with trinitrobenzene sulfonate.", "content": "A comparative study of SV40-transformed fibroblast plasma membrane proteins labelled by enzymatic iodination or with trinitrobenzene sulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372082"}
{"pmid": "4372084", "title": "Hepatic action of vasopressin: lack of a role for adenosine-3',5'-cyclic monophosphate.", "content": "Hepatic action of vasopressin: lack of a role for adenosine-3',5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372084"}
{"pmid": "4372086", "title": "Glycogen synthetase kinase 2 (GSK 2); the identification of a new protein kinase in skeletal muscle.", "content": "Glycogen synthetase kinase 2 (GSK 2); the identification of a new protein kinase in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372086"}
{"pmid": "4372085", "title": "Hormone-stimulated cAMP production in human placenta perfused in vitro.", "content": "Hormone-stimulated cAMP production in human placenta perfused in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372085"}
{"pmid": "4372087", "title": "Inhibition of lipolysis in bovine adipose tissue by butyrate and beta-hydroxybutyrate.", "content": "Inhibition of lipolysis in bovine adipose tissue by butyrate and beta-hydroxybutyrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372087"}
{"pmid": "4372088", "title": "Conformational changes at membranes of target cells induced by the peptide hormone angiotensin. A spin label study.", "content": "Conformational changes at membranes of target cells induced by the peptide hormone angiotensin. A spin label study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372088"}
{"pmid": "4372089", "title": "NAD levels in 3T3 cells during exponential growth and density-dependent inhibition of growth.", "content": "NAD levels in 3T3 cells during exponential growth and density-dependent inhibition of growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372089"}
{"pmid": "4372090", "title": "Nicotinamide 1, N6-ethenoadenine dinucleotide, a coenzyme for glutamate dehydrogenase.", "content": "Nicotinamide 1, N6-ethenoadenine dinucleotide, a coenzyme for glutamate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372090"}
{"pmid": "4372091", "title": "A receptor for testosterone in mature rat testes.", "content": "A receptor for testosterone in mature rat testes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372091"}
{"pmid": "4372093", "title": "The effect of catecholamine analogues upon amylase secretion from the mouse parotid gland in vivo:relationship to changes in cyclic AMP and cyclic GMP levels.", "content": "The effect of catecholamine analogues upon amylase secretion from the mouse parotid gland in vivo:relationship to changes in cyclic AMP and cyclic GMP levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372093"}
{"pmid": "4372092", "title": "The amino acid sequence of cytochrome c from Solanum tuberosum (potato).", "content": "The amino acid sequence of cytochrome c from Solanum tuberosum (potato).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372092"}
{"pmid": "4372094", "title": "The carbohydrate composition of submitochondrial fractions from rat liver.", "content": "The carbohydrate composition of submitochondrial fractions from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372094"}
{"pmid": "4372096", "title": "A peptic phosphopeptide from the active site of pea seed nucleoside diphosphate kinase.", "content": "A peptic phosphopeptide from the active site of pea seed nucleoside diphosphate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372096"}
{"pmid": "4372095", "title": "Specific spin-labelling of the energy-coupling system of mitochondria.", "content": "Specific spin-labelling of the energy-coupling system of mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372095"}
{"pmid": "4372097", "title": "Synthesis of cytochrome oxidase components in isolated mitochondria of Neurosora crassa.", "content": "Synthesis of cytochrome oxidase components in isolated mitochondria of Neurosora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372097"}
{"pmid": "4372098", "title": "Activation of adenyl cyclase in the early phase of germination.", "content": "Activation of adenyl cyclase in the early phase of germination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372098"}
{"pmid": "4372099", "title": "Transcription of the Col E1 genome in colicinogenic E. coli strains during induction with mitomycin C.", "content": "Transcription of the Col E1 genome in colicinogenic E. coli strains during induction with mitomycin C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372099"}
{"pmid": "4372100", "title": "Defective protein phosphorylation in membranes of hereditary spherocytosis erythrocytes.", "content": "Defective protein phosphorylation in membranes of hereditary spherocytosis erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372100"}
{"pmid": "4372101", "title": "EPR detection of deuteriochlorophyll cation-radicals arising at its photoreaction with quinone at low temperature.", "content": "EPR detection of deuteriochlorophyll cation-radicals arising at its photoreaction with quinone at low temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372101"}
{"pmid": "4372102", "title": "Energy transduction in photosynthetic bacteria. The nature of cytochrome C oxidase in the respiratory chain of Rhodopseudomonas capsulata.", "content": "Energy transduction in photosynthetic bacteria. The nature of cytochrome C oxidase in the respiratory chain of Rhodopseudomonas capsulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372102"}
{"pmid": "4372103", "title": "Reaction of cytochrome C oxidase with CO: involvement of the invisible copper.", "content": "Reaction of cytochrome C oxidase with CO: involvement of the invisible copper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372103"}
{"pmid": "4372104", "title": "Molecular weight determination of the chymotrypsin-like protease of the larvae of the hornet, Vespa orientalis, by affinity labeling of the active center.", "content": "Molecular weight determination of the chymotrypsin-like protease of the larvae of the hornet, Vespa orientalis, by affinity labeling of the active center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372104"}
{"pmid": "4372105", "title": "LH-RH-receptor interaction is inhibited by des-His--2-des-Gly--10-LH-RH-ethylamide.", "content": "LH-RH-receptor interaction is inhibited by des-His--2-des-Gly--10-LH-RH-ethylamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372105"}
{"pmid": "4372106", "title": "Vitamin D: the vitamin and the hormone.", "content": "Vitamin D: the vitamin and the hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372106"}
{"pmid": "4372107", "title": "Present knowledge of the role of chromium.", "content": "Present knowledge of the role of chromium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372107"}
{"pmid": "4372109", "title": "Lesions associated with impacted teeth.", "content": "Lesions associated with impacted teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372109"}
{"pmid": "4372110", "title": "The nature of pain.", "content": "The nature of pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372110"}
{"pmid": "4372111", "title": "Xanthomatosis and hyperlipoproteinemia; a review.", "content": "Xanthomatosis and hyperlipoproteinemia; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372111"}
{"pmid": "4372113", "title": "A developmental study on the capacity of rabbit granulosa cells to respond to trophic hormones and secrete progesterone in vitro.", "content": "A developmental study on the capacity of rabbit granulosa cells to respond to trophic hormones and secrete progesterone in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372113"}
{"pmid": "4372112", "title": "Testosterone-protein binding in cytosol of rat anterior hypophysis in vitro: evidence for a specific receptor.", "content": "Testosterone-protein binding in cytosol of rat anterior hypophysis in vitro: evidence for a specific receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372112"}
{"pmid": "4372114", "title": "Development of phosphodiesterase activity in the chick retina.", "content": "Development of phosphodiesterase activity in the chick retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372114"}
{"pmid": "4372115", "title": "Increased hepatic gluconeogenesis without a rise of glucagon secretion in rats fed a high fat diet.", "content": "Increased hepatic gluconeogenesis without a rise of glucagon secretion in rats fed a high fat diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372115"}
{"pmid": "4372116", "title": "Dietary and drug treatment of hyperlipidemia in diabetes.", "content": "Dietary and drug treatment of hyperlipidemia in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372116"}
{"pmid": "4372118", "title": "Quantitative study on thromboplastin in various strains of Yoshida ascites hepatoma cells of rat.", "content": "Quantitative study on thromboplastin in various strains of Yoshida ascites hepatoma cells of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372118"}
{"pmid": "4372119", "title": "Inhibitory effect of Capsella bursa-pastoris on hepatocarcino-genesis induced by 3-methyl-4-(dimethylamino)azobenzene in rats.", "content": "Inhibitory effect of Capsella bursa-pastoris on hepatocarcino-genesis induced by 3-methyl-4-(dimethylamino)azobenzene in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372119"}
{"pmid": "4372120", "title": "Dual infection of hamsters with Adenovirus type 12 and type 6.", "content": "Dual infection of hamsters with Adenovirus type 12 and type 6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372120"}
{"pmid": "4372121", "title": "Selective distribution of the radioactivity in nerve tissues of the mouse after intravenous administration of 14C-labeled N-methyl-N-nitrosoguanidine.", "content": "Selective distribution of the radioactivity in nerve tissues of the mouse after intravenous administration of 14C-labeled N-methyl-N-nitrosoguanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372121"}
{"pmid": "4372122", "title": "Microsomal acetylesterase activity in tumor-bearing rats.", "content": "Microsomal acetylesterase activity in tumor-bearing rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372122"}
{"pmid": "4372123", "title": "Collision tumor of the stomach. Report of two cases.", "content": "Collision tumor of the stomach. Report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372123"}
{"pmid": "4372124", "title": "Effects of cholera toxin and phosphodiesterase inhibitors on fluid transport and cyclic adenosine 3',5'-monophosphate concentrations in rabbit gallbladder.", "content": "Effects of cholera toxin and phosphodiesterase inhibitors on fluid transport and cyclic adenosine 3',5'-monophosphate concentrations in rabbit gallbladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372124"}
{"pmid": "4372125", "title": "Endoscopic retrograde cholangiopancreatography in the diagnosis of jaundice associated with ulcerative colitis.", "content": "Endoscopic retrograde cholangiopancreatography in the diagnosis of jaundice associated with ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372125"}
{"pmid": "4372126", "title": "Cytodiagnosis of pancreatic malignant tumors by aspiration, under direct vision, using a duodenal fiberscope.", "content": "Cytodiagnosis of pancreatic malignant tumors by aspiration, under direct vision, using a duodenal fiberscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372126"}
{"pmid": "4372128", "title": "Further studies on the hormonal control of melanophores and iridophores isolated from bullfrog tadpoles.", "content": "Further studies on the hormonal control of melanophores and iridophores isolated from bullfrog tadpoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372128"}
{"pmid": "4372129", "title": "A five-step approach to antimicrobial medication. 2. Urinary tract infections.", "content": "A five-step approach to antimicrobial medication. 2. Urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372129"}
{"pmid": "4372130", "title": "Electron microscopic study on the jejunal mucosa in human cholera.", "content": "Electron microscopic study on the jejunal mucosa in human cholera. Small intestinal mucosa obtained from six fasting patients with cholera by a peroral biopsy technique was studied with the electron microscope. The cultures of their rectal swabs were all positive for Vibrio cholerae. In the absorptive cells, large pseudopod-like cytoplasmic processes with deformed microvilli or without microvilli (blebs) projected into the intestinal lumen from the apical cell surface, interrupting the microvillous border. In the crypts some of the undifferentiated crypt cells possessed pseudopod-like cytoplasmic projections which extended into the crypt lumen. The swelling of mitochondria, the disappearance of their cristae, an increase in the number of vesicles of the Golgi apparatus, and the dilatation and vesiculation of endoplasmic reticulum were observed in the epithelial cells. The apical portion of the cells became oedematous in some of the epithelial cells. Cytoplasmic fragments enclosed by a plasma membrane, desquamated epithelial cells, cytoplasmic organelles, and secretory granules were lying free in the intestinal lumen.Marked irregular widening of the interepithelial spaces in the jejunal mucoa was observed at the midvillous area. Many cystic vacuoles were present in the cytoplasm of epithelial cells. The possibility of fluids being transported from blood vessels to intestinal lumina through the interepithelial spaces, and the significance of these pathological findings in human cholera are discussed in this study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372130"}
{"pmid": "4372131", "title": "Histochemical studies on the mucous membrane of the jejunum after vagotomy and pyloromyotomy in white rats.", "content": "Histochemical studies on the mucous membrane of the jejunum after vagotomy and pyloromyotomy in white rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372131"}
{"pmid": "4372132", "title": "Ultrastructure of renal glomerulus under conditions of hypercalcemia induced with vitamin D3.", "content": "Ultrastructure of renal glomerulus under conditions of hypercalcemia induced with vitamin D3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372132"}
{"pmid": "4372133", "title": "Comparative studies on the behavior of C cells in the rat thyroid under conditions of hypercalcemia induced with vitamin D3 and calcium gluconate.", "content": "Comparative studies on the behavior of C cells in the rat thyroid under conditions of hypercalcemia induced with vitamin D3 and calcium gluconate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372133"}
{"pmid": "4372134", "title": "Oxidative phosphorylation in a yeast mutant lacking alpha-ketoglutarate dehydrogenase activity.", "content": "Oxidative phosphorylation in a yeast mutant lacking alpha-ketoglutarate dehydrogenase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372134"}
{"pmid": "4372135", "title": "Recent developments in the chemistry of penicillins.", "content": "Recent developments in the chemistry of penicillins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372135"}
{"pmid": "4372136", "title": "Structure, chemistry, and biosynthesis of the melanins.", "content": "Structure, chemistry, and biosynthesis of the melanins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372136"}
{"pmid": "4372138", "title": "Interactions of 17 beta-estradiol and L-epinephrine on the rat uterus.", "content": "Interactions of 17 beta-estradiol and L-epinephrine on the rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372138"}
{"pmid": "4372139", "title": "Study of the effects of morphine on adrenal corticosteroids, ascorbic acid and catecholamines in unanaesthetized and anaesthetized cats.", "content": "Study of the effects of morphine on adrenal corticosteroids, ascorbic acid and catecholamines in unanaesthetized and anaesthetized cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372139"}
{"pmid": "4372140", "title": "Molecular and catalytic properties of unspecific carboxylesterases (EC 3-1-1-1).", "content": "Molecular and catalytic properties of unspecific carboxylesterases (EC 3-1-1-1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372140"}
{"pmid": "4372143", "title": "Stereospecificities in the metabolic reactions of the four isomeric sphinganines (dihydrosphingosines) in rat liver.", "content": "Stereospecificities in the metabolic reactions of the four isomeric sphinganines (dihydrosphingosines) in rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372143"}
{"pmid": "4372145", "title": "Studies on the B-protein of human serum beta-lipoprotein using SDS-polyacrylamide gel electrophoresis.", "content": "Studies on the B-protein of human serum beta-lipoprotein using SDS-polyacrylamide gel electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372145"}
{"pmid": "4372146", "title": "Magnetic resonance studies on the binding of manganese to D-fructose-1,6-diphosphate 1-phosphohydrolase (hexose-1,6-diphosphatase).", "content": "Magnetic resonance studies on the binding of manganese to D-fructose-1,6-diphosphate 1-phosphohydrolase (hexose-1,6-diphosphatase).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372146"}
{"pmid": "4372147", "title": "Metabolic transformation of colchicine. I. The oxidative formation of products from colchicine in the Udenfriend system.", "content": "Metabolic transformation of colchicine. I. The oxidative formation of products from colchicine in the Udenfriend system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372147"}
{"pmid": "4372149", "title": "Sphingosine kinase in blood platelets.", "content": "Sphingosine kinase in blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372149"}
{"pmid": "4372148", "title": "Different half-lives of nicotinamide and adenine moieties of NAD in HeLa S3 cultures.", "content": "Different half-lives of nicotinamide and adenine moieties of NAD in HeLa S3 cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372148"}
{"pmid": "4372151", "title": "Expression of the mitochondria genome in wild type and in extracellular mutants of Neurospora crassa.", "content": "Expression of the mitochondria genome in wild type and in extracellular mutants of Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372151"}
{"pmid": "4372152", "title": "The orientation of serologically active phospholipids in mitochondrial membranes, I.", "content": "The orientation of serologically active phospholipids in mitochondrial membranes, I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372152"}
{"pmid": "4372153", "title": "The orientation of serologically active phospholipids in mitochondrial membranes, II. Studies in vitro with a complement fixation reaction.", "content": "The orientation of serologically active phospholipids in mitochondrial membranes, II. Studies in vitro with a complement fixation reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372153"}
{"pmid": "4372155", "title": "Mitochondrial H2O2 formation at site II.", "content": "Mitochondrial H2O2 formation at site II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372155"}
{"pmid": "4372157", "title": "Gangliosides of extraneural organs.", "content": "Gangliosides of extraneural organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372157"}
{"pmid": "4372159", "title": "Continuous synthesis of NAD in a nuclear column.", "content": "Continuous synthesis of NAD in a nuclear column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372159"}
{"pmid": "4372160", "title": "Studies on ADP-ribose ribosylation in rat liver nuclei.", "content": "Studies on ADP-ribose ribosylation in rat liver nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372160"}
{"pmid": "4372161", "title": "Radiographic determination of excessive bone loss in Alaskan Eskimos.", "content": "Radiographic determination of excessive bone loss in Alaskan Eskimos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372161"}
{"pmid": "4372162", "title": "The distribution of some erythrocyte and serum enzyme group systems in the Mahishyas and the Muslims of 24-Parganas, West Bengal.", "content": "The distribution of some erythrocyte and serum enzyme group systems in the Mahishyas and the Muslims of 24-Parganas, West Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372162"}
{"pmid": "4372163", "title": "Metabolism of cholesterol in rats under dietary necrosis.", "content": "Metabolism of cholesterol in rats under dietary necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372163"}
{"pmid": "4372164", "title": "Certain biochemical changes in the root meristem cells of Vicia faba treated with mitomycin C.", "content": "Certain biochemical changes in the root meristem cells of Vicia faba treated with mitomycin C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372164"}
{"pmid": "4372165", "title": "A dipole mechanism of nervous transmission.", "content": "A dipole mechanism of nervous transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372165"}
{"pmid": "4372166", "title": "Effect of age on the composition of major phospholipids of mycobacteria.", "content": "Effect of age on the composition of major phospholipids of mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372166"}
{"pmid": "4372168", "title": "Immunological relationship between antigens induced by leukemia virus & mammary tumor virus in an inbred mouse strain.", "content": "Immunological relationship between antigens induced by leukemia virus & mammary tumor virus in an inbred mouse strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372168"}
{"pmid": "4372167", "title": "Antisera to carcinoembryonic antigen: removal of persistant impurities.", "content": "Antisera to carcinoembryonic antigen: removal of persistant impurities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372167"}
{"pmid": "4372169", "title": "Jaagziekte & maedi of sheep & goats transmitted in laboratory animals.", "content": "Jaagziekte & maedi of sheep & goats transmitted in laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372169"}
{"pmid": "4372171", "title": "Recurrent cutaneous herpes simplex in hairless mice.", "content": "Recurrent cutaneous herpes simplex in hairless mice. Passively immunized hairless mice were inoculated cutaneously with herpes simplex virus. Thirty-nine days later, when the primary cutaneous lesions had completely healed, the mice were treated subcutaneously with prednisone. Within 12 to 30 days after starting prednisone treatment, herpesvirus was recovered by skin swabs from 12 of 71 (17%) of the treated mice. This new model has potential application for understanding and treating recurrent cutaneous herpes infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372171"}
{"pmid": "4372170", "title": "Stimulation of peripheral blood lymphocytes by herpes simplex virus in vitro.", "content": "Stimulation of peripheral blood lymphocytes by herpes simplex virus in vitro. A method for stimulating sensitized lymphocytes by inactivated herpes simplex virus was established by using cultures of washed whole blood cells. The development of the immune response of herpes simplex virus-infected guinea pigs was examined at different times in the 4-month period after infection. Humoral and cellular immune responses were compared in individual animals by measuring lymphocyte stimulation ratios and neutralizing serum antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372170"}
{"pmid": "4372174", "title": "Relationship of Ehrlichia canis-infected mononuclear cells to blood vessels of lungs.", "content": "Relationship of Ehrlichia canis-infected mononuclear cells to blood vessels of lungs. The lung tissue of six dogs with ehrlichiosis and two control dogs was examined with the electron microscope. Mononuclear cells containing inclusions (morulae) of Ehrlichia canis were adhered at one or more sites to the luminal surfaces of endothelial cells of arterioles or capillaries by way of interdigitations or areas of adherence, or an endothelial cell-bound mononuclear cell was chained to another parasitized or nonparasitized mononuclear cell in the lumen. The bifurcation of arterioles was the most common site at which mononuclear cells clung to the endothelium. Cell-free bodies (morulae), enclosed by a single membrane, were present in the lumens of arterioles. Such cell-free bodies were swollen and vesiculated as compared with intracytoplasmic inclusions (morulae) in mononuclear cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372174"}
{"pmid": "4372173", "title": "Differentiation of strains of infectious bovine rhinotracheitis virus by neutralization kinetics with late 19S rabbit antibodies.", "content": "Differentiation of strains of infectious bovine rhinotracheitis virus by neutralization kinetics with late 19S rabbit antibodies. Two vaccine, two respiratory (infectious bovine rhinotracheitis [IBR]), and two genital (infectious pustular vulvovaginitis [IPV]) strains of infectious bovine rhinotracheitis virus were compared by neutralization kinetics using late 19S antibody (AB). The two vaccine strains were indistinguishable from one another, but were neutralized far more rapidly than the other four strains when either anti-IBR or anti-IPV 19S AB was used. The two IPV strains were indistinguishable from one another, but were neutralized significantly more rapidly than the two IBR strains when anti-IBR 19S AB was used. The 2 IBR strains were neutralized at a similar rate with the latter globulin preparation. Almost identical results were obtained with anti-IPV 19S AB, except that one IPV strain was neutralized at a rate similar to the IBR strains. However, when early and late rabbit 7S AB were used, IBR strains could not be distinguished from IPV strains by neutralization kinetics. Preliminary experiments indicated that both early and late 19S rabbit antibodies neutralized the homologous strain more rapidly than the heterologous strain, but the difference was more noticeable with late 19S AB. It was also determined that neutralization of IBR-IPV virus by specific early and late 19S rabbit AB and early 7S rabbit AB was markedly enhanced by guinea pig complement. Neutralization of this virus by late 7S AB, however, was only slightly enhanced by complement. These results suggest that vaccine strains of IBR-IPV virus may be distinguished by neutralization kinetics with late 19S rabbit AB, and that genital and respiratory strains may possibly also be distinguishable with some 19S AB preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372173"}
{"pmid": "4372175", "title": "Equine infectious anemia virus from infected horse serum.", "content": "Equine infectious anemia virus from infected horse serum. Equine infectious anemia virus was purified from infected horse serum samples. Electron microscope observation on negatively stained preparations of purified virus showed roughly spherical particles sized between 100 and 200 nm in diameter. In disrupted particles, an envelope was visible but no internal structure could be resolved. Since the purified virus fraction had a strong antigenic activity to antiserum in immunodiffusion reaction, these particles are thought to be the causative virus of equine infectious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372175"}
{"pmid": "4372172", "title": "Comparison of the action of Escherichia coli enterotoxin on the thymocyte adenylate cyclase-cyclic adenosine monophosphate system to that of cholera toxin and prostaglandin E1.", "content": "Comparison of the action of Escherichia coli enterotoxin on the thymocyte adenylate cyclase-cyclic adenosine monophosphate system to that of cholera toxin and prostaglandin E1. Mouse thymocytes were used to compare mechanisms by which Vibrio cholerae and heat-labile Escherichia coli enterotoxins activate the adenylate cyclase-cyclic adenosine monophosphate (AMP) system. Both enterotoxins had their time-delayed increase in cyclic AMP neutralized by antisera to V. cholerae or E. coli enterotoxin, blocked by low concentrations of ganglioside G(M1), and destroyed by prior heating. Enterotoxin activation of adenylate cyclase was similarly affected. By contrast, prostaglandin E(1)-mediated increases in cyclic AMP were not affected by specific antitoxins or gangliosides. Combination of maximal stimulatory doses of both enterotoxins did not produce additive increases in cyclic AMP. Wash experiments suggested that both enterotoxins bind rapidly and tightly to thymocytes at 37 C. However, lowering the incubation temperature to 8 C reduced the affinity of E. coli enterotoxin but not cholera toxin for thymocytes. Results suggest that heat-labile E. coli enterotoxin and cholera enterotoxin may activate the same adenylate cyclase enzyme by similar mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372172"}
{"pmid": "4372176", "title": "Comparative studies of the Smith and Raynaud strains of murine cytomegalovirus.", "content": "Comparative studies of the Smith and Raynaud strains of murine cytomegalovirus. A number of the biological, biophysical, and immunological parameters of the Smith and Raynaud strains of murine cytomegalovirus were compared. The two strains were found to be indistinguishable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372176"}
{"pmid": "4372177", "title": "Neutralizing activity in isolated serum antibody fractions from visna-infected sheep.", "content": "Neutralizing activity in isolated serum antibody fractions from visna-infected sheep. The neutralization technique was used to detect specific antibodies against visna virus in isolated immunoglobulin (Ig) G(1), IgG(2), and IgM fractions of visna-infected sheep serum. The neutralizing antibodies were present chiefly in the IgG(1) class. Low amount of activity was demonstrated in the IgM class, but no significant activity was seen in the IgG(2) class.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372177"}
{"pmid": "4372178", "title": "Comparison of antibodies against different viruses in cerebrospinal fluid and serum samples from patients with multiple sclerosis.", "content": "Comparison of antibodies against different viruses in cerebrospinal fluid and serum samples from patients with multiple sclerosis. The occurrence of a local production in the central nervous system (CNS) of antibodies against different selected viruses was analyzed by comparison of titers in serum and cerebrospinal fluid samples from groups of 50 patients with multiple sclerosis from Finland, Norway, and Sweden. Measles antibodies were determined in hemagglutination inhibition, hemolysis inhibition, and nucleocapsid complement fixation tests; mumps, parainfluenza virus type 1, and rubella virus antibodies were determined in hemagglutination inhibition tests; and herpes simplex virus type 1 antibodies were determined in passive hemagglutination tests. For reference purposes tests were also made for adenovirus antibodies in penton hemagglutination enhancement tests and poliovirus antibodies in neutralization enhancement tests. Among the 150 multiple sclerosis patients, a local production of antibodies against measles virus was found in the CNS in 57%, against rubella virus in 19%, mumps virus in 15%, herpes simplex virus type 1 in 11%, and parainfluenza virus type 1 (Sendai) in 3%. A local production in the CNS of antibodies against any of the viruses studied was found in 71% of multiple sclerosis patients. These included 48, 16, and 7% that produced antibodies to one, two, and three or more viruses, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372178"}
{"pmid": "4372180", "title": "Virus production and release, cell longevity, and cloning efficiency of chicken embryo fibroblasts infected with Rous sarcoma virus.", "content": "Virus production and release, cell longevity, and cloning efficiency of chicken embryo fibroblasts infected with Rous sarcoma virus. Continuous virus production is a characteristic of chicken embryo fibroblasts (CEF) infected and transformed by a nondefective Schmidt-Ruppin subgroup A Rous sarcoma virus. This virus production has been examined with particular attention to the amount of newly budded virus which remained cell-associated, and to the amount and degree of viral aggregation at the cell surface and in the fluid tissue culture medium. The total biologically active virus associated with a Schmidt-Ruppin subgroup A Rous sarcoma virus-infected CEF culture was divided almost equally between that portion of virus which was present in the fluid medium and that portion which was cell-associated. Various mechanical and enzymatic methods were used to remove cell-bound virus and to disperse aggregates of virus in the tissue culture medium to assess cell production of virus per hour accurately, which was determined as an average of 16.4 focus-forming units per cell per hour. With appropriate culture conditions, it was found that Schmidt-Ruppin subgroup A Rous sarcoma virus-infected and -transformed CEF replicated faster, could be passaged more times, and grew to higher cell densities than did normal CEF and CEF infected with a subgroup A Rous associated virus. Subgroup A Rous sárcoma virus-infected CEF cloned with much lower efficiency than did subgroup A Rous associated virus-infected CEF or normal CEF. Experiments employing a temperature-sensitive mutant of subgroup A Schmidt-Ruppin Rous sarcoma virus- and Rous associated virus-infected CEF indicated that the poor cloning efficiency of Schmidt-Ruppin subgroup A Rous sarcoma virus infected cells was not due to the constant production of virus but was probably related to some property associated with transformation of the cell by Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372180"}
{"pmid": "4372179", "title": "Cell-mediated immunity in humans during viral infection: dermal hypersensitivity and in vitro lymphocyte proliferation during mild viral respiratory infections.", "content": "Cell-mediated immunity in humans during viral infection: dermal hypersensitivity and in vitro lymphocyte proliferation during mild viral respiratory infections. In vitro lymphocyte proliferation in response to phytohemagglutinin and streptokinase-streptodornase and delayed dermal hypersensitivity to several antigens were assessed in patients with mild viral upper respiratory infections. The response to phytohemagglutinin in 18 patients was not diminished during the viral infection. Deoxyribonucleic acid synthesis induced by streptokinase-streptodornase remained unaffected by the viral illness in five patients, and skin test reactivity was not depressed during the viral infection. Thus, it appeared that localized viral upper respiratory infections were not associated with suppression of systemic cell-mediated immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372179"}
{"pmid": "4372181", "title": "Effect of parainfluenza-3 virus neuraminidase on the structure of the gel phase of bovine nasal secretion.", "content": "Effect of parainfluenza-3 virus neuraminidase on the structure of the gel phase of bovine nasal secretion. The gel phase of bovine nasal secretion was separated from the liquid phase and exposed to parainfluenza-3 virus or Vibrio cholerae neuraminidase under optimal in vitro conditions. N-Acetylneuraminic acid was released from the gel by either neuraminidase. The release of N-acetylneuraminic acid was accompanied by a decrease in the net negative charge of the gel, as evidenced by free zone electrophoresis. Scanning electron microscopy showed that after exposure to neuraminidases the regular network structure of the untreated gel attained a coarse, irregular structure. Samples of gel incubated with 0.15 M sodium chloride under similar conditions did not show changes in the net charge or morphology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372181"}
{"pmid": "4372182", "title": "Pathogenesis of human parainfluenza type 3 virus infection in hamster tracheal organ culture.", "content": "Pathogenesis of human parainfluenza type 3 virus infection in hamster tracheal organ culture. Hamster tracheal organ culture was employed as a model for the study of the pathogenesis of human parainfluenza type 3 virus infection. It clearly supported replication of the virus over a 2-week period of time. Infected tracheal explants were examined with light, electron, and immunofluorescence microscopy. They exhibited specific cytopathologic alterations including nuclear swelling and chromatin margination, multinucleated syncytia and binucleated epithelial cells, and fibroblasts and chondrocytes. Focal destruction and denudation of the respiratory epithelium occurred in later stages of infection. Virus was detected in close association with cilia and was observed budding off the unit membrane of epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372182"}
{"pmid": "4372183", "title": "Induction of disseminated virulent cytomegalovirus infection by immunosuppression of naturally chronically infected wild mice.", "content": "Induction of disseminated virulent cytomegalovirus infection by immunosuppression of naturally chronically infected wild mice. Wild mice immunosuppressed with antithymocytic sera show a high incidence of disseminated virulent cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372183"}
{"pmid": "4372184", "title": "The mechanism of the adjuvant effect of Bordetella pertussis: the substance responsible for the selective enhancement of IgE antibody production.", "content": "The mechanism of the adjuvant effect of Bordetella pertussis: the substance responsible for the selective enhancement of IgE antibody production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372184"}
{"pmid": "4372185", "title": "Mast cell degranulation: a comparison of the inhibitory actions of disodium cromoglycate, drugs known to influence the level of intracellular cyclic nucleotide and diisopropylfluorophosphate (DFP).", "content": "Mast cell degranulation: a comparison of the inhibitory actions of disodium cromoglycate, drugs known to influence the level of intracellular cyclic nucleotide and diisopropylfluorophosphate (DFP).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372185"}
{"pmid": "4372186", "title": "Time course of homocytotropic and passive haemagglutinating antibody synthesis in the marsupial Setonix brachyurus (the quokka).", "content": "Time course of homocytotropic and passive haemagglutinating antibody synthesis in the marsupial Setonix brachyurus (the quokka).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372186"}
{"pmid": "4372187", "title": "Arthropod-borne disease as a possible factor limiting the distribution of birds.", "content": "Arthropod-borne disease as a possible factor limiting the distribution of birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372187"}
{"pmid": "4372188", "title": "Radioassays for the proteolytic enzyme secreted by living eggs of Schistosoma mansoni.", "content": "Radioassays for the proteolytic enzyme secreted by living eggs of Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372188"}
{"pmid": "4372189", "title": "Polyhydric alcohols: structure-supporting solvents for polypeptides and proteins.", "content": "Polyhydric alcohols: structure-supporting solvents for polypeptides and proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372189"}
{"pmid": "4372190", "title": "Some considerations of after-care: problems of therapy, training and preceptoring.", "content": "Some considerations of after-care: problems of therapy, training and preceptoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372190"}
{"pmid": "4372191", "title": "Effects of x-radiation on growth and function of the repair blastema (granulation tissue). III. Measurements of pharmacodynamic activity in vitro.", "content": "Effects of x-radiation on growth and function of the repair blastema (granulation tissue). III. Measurements of pharmacodynamic activity in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372191"}
{"pmid": "4372192", "title": "An insoluble structural glycoprotein a major constituent of the zonula Zinni.", "content": "An insoluble structural glycoprotein a major constituent of the zonula Zinni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372192"}
{"pmid": "4372195", "title": "Effect of oxathiol on the uptake of absorbed doses from polonium-210 in the rat.", "content": "Effect of oxathiol on the uptake of absorbed doses from polonium-210 in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372195"}
{"pmid": "4372193", "title": "Antagonism of renal angiographic effects of cadmium by zinc.", "content": "Antagonism of renal angiographic effects of cadmium by zinc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372193"}
{"pmid": "4372200", "title": "Familial epilepsy and yellow teeth--a disease of the CNS associated with enamel hypoplasia.", "content": "Familial epilepsy and yellow teeth--a disease of the CNS associated with enamel hypoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372200"}
{"pmid": "4372201", "title": "Growth and body proportions in 54 boys and men with Klinefelter's syndrome.", "content": "Growth and body proportions in 54 boys and men with Klinefelter's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372201"}
{"pmid": "4372203", "title": "On the binding of Schiff's reagent in the PAS reaction: effects of molecular configurations in models.", "content": "On the binding of Schiff's reagent in the PAS reaction: effects of molecular configurations in models.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372203"}
{"pmid": "4372204", "title": "Organ culture of adult guinea-pig intestine. II. Biochemical and ultracytochemical findings.", "content": "Organ culture of adult guinea-pig intestine. II. Biochemical and ultracytochemical findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372204"}
{"pmid": "4372205", "title": "Fine structure of the pars intermedia in the rhesus monkey, Macaca mulatta.", "content": "Fine structure of the pars intermedia in the rhesus monkey, Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372205"}
{"pmid": "4372206", "title": "Fine structure, origin and fate of extracellular materials in the interspace between the presumptive lens and presumptive retina of the chick embryo.", "content": "Fine structure, origin and fate of extracellular materials in the interspace between the presumptive lens and presumptive retina of the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372206"}
{"pmid": "4372194", "title": "Angiography in hepatic cysts and tumors in the rat.", "content": "Angiography in hepatic cysts and tumors in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372194"}
{"pmid": "4372208", "title": "Studies on energy and electron transfer systems in the green photosynthetic bacterium Chloropseudomonas ethylica strain 2-K. II. Composition of pigments and electron transfer systems.", "content": "Studies on energy and electron transfer systems in the green photosynthetic bacterium Chloropseudomonas ethylica strain 2-K. II. Composition of pigments and electron transfer systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372208"}
{"pmid": "4372207", "title": "The effect of transection of the glossopharyngeal nerve upon the structure, cholinesterase activity and innervation of taste buds in rabbits.", "content": "The effect of transection of the glossopharyngeal nerve upon the structure, cholinesterase activity and innervation of taste buds in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372207"}
{"pmid": "4372209", "title": "The inhibition mechanism of the cytochrome oxidase reaction. V. Quantitative analyses of the formation of the kinetically inactive complex of cytochrome oxidase with cyanide.", "content": "The inhibition mechanism of the cytochrome oxidase reaction. V. Quantitative analyses of the formation of the kinetically inactive complex of cytochrome oxidase with cyanide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372209"}
{"pmid": "4372211", "title": "Adenylate kinase activity. In ciliary axonemes isolated from Tetrahymena pyriformis.", "content": "Adenylate kinase activity. In ciliary axonemes isolated from Tetrahymena pyriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372211"}
{"pmid": "4372210", "title": "The isolation and characterization of glycopeptides from plasma membranes of an ascites hepatoma, AH 66.", "content": "The isolation and characterization of glycopeptides from plasma membranes of an ascites hepatoma, AH 66.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372210"}
{"pmid": "4372212", "title": "Studies on triglyceride synthesis in lipid micelles from adipose tissue.", "content": "Studies on triglyceride synthesis in lipid micelles from adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372212"}
{"pmid": "4372214", "title": "The role of direct phosphorylation in the mechanism of adenosine utilization for nucleotide synthesis in mouse erythrocytes.", "content": "The role of direct phosphorylation in the mechanism of adenosine utilization for nucleotide synthesis in mouse erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372214"}
{"pmid": "4372213", "title": "Carboxypeptidase CN. II. Stability and some chemical and kinetic properties.", "content": "Carboxypeptidase CN. II. Stability and some chemical and kinetic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372213"}
{"pmid": "4372215", "title": "Inhibition of protein kinase and cyclic AMP phosphodiesterase by eritadenine isoamyl ester. A possible mechanism for its biphasic effects on cyclic AMP-dependent lipolysis, steroidogenesis and amino acid uptake.", "content": "Inhibition of protein kinase and cyclic AMP phosphodiesterase by eritadenine isoamyl ester. A possible mechanism for its biphasic effects on cyclic AMP-dependent lipolysis, steroidogenesis and amino acid uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372215"}
{"pmid": "4372217", "title": "Pyrophosphate:D-fructose 6-phosphate 1-phosphotransferase. A new enzyme with the glycolytic function of 6-phosphofructokinase.", "content": "Pyrophosphate:D-fructose 6-phosphate 1-phosphotransferase. A new enzyme with the glycolytic function of 6-phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372217"}
{"pmid": "4372216", "title": "Studies of the insulin-like actions of polyamines on lipid and glucose metabolism in adipose tissue cells.", "content": "Studies of the insulin-like actions of polyamines on lipid and glucose metabolism in adipose tissue cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372216"}
{"pmid": "4372218", "title": "Cyclic adenosine 3':5'-monophosphate and cyclic guanosine 3':5'-monophosphate phosphodiesterase activities are under separate genetic control.", "content": "Cyclic adenosine 3':5'-monophosphate and cyclic guanosine 3':5'-monophosphate phosphodiesterase activities are under separate genetic control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372218"}
{"pmid": "4372219", "title": "Cytidine 5'-monophosphosialic acid hydrolase. Subcellular location and properties.", "content": "Cytidine 5'-monophosphosialic acid hydrolase. Subcellular location and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372219"}
{"pmid": "4372220", "title": "Studies on receptor-mediated activation of adenylyl cyclases. I. Preparation and description of general properties of an adenylyl cyclase system in beef renal medullary membranes sensitive to neurohypophyseal hormones.", "content": "Studies on receptor-mediated activation of adenylyl cyclases. I. Preparation and description of general properties of an adenylyl cyclase system in beef renal medullary membranes sensitive to neurohypophyseal hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372220"}
{"pmid": "4372221", "title": "Studies on receptor-mediated activation of adenylyl cyclases. II. Nucleotide and nucleoside regulation of the activities of the beef renal medullary adenylyl cyclase and their stimulation by neurohypophyseal hormones.", "content": "Studies on receptor-mediated activation of adenylyl cyclases. II. Nucleotide and nucleoside regulation of the activities of the beef renal medullary adenylyl cyclase and their stimulation by neurohypophyseal hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372221"}
{"pmid": "4372222", "title": "Studies on receptor-mediated activation of adenylyl cyclases. III. Regulation by purine nucleotides of the activation of adenylyl cyclases from target organs for prostaglandins, luteinizing hormone, neurohypophyseal hormones and catecholamines. Tissue- and hormone-dependent variations.", "content": "Studies on receptor-mediated activation of adenylyl cyclases. III. Regulation by purine nucleotides of the activation of adenylyl cyclases from target organs for prostaglandins, luteinizing hormone, neurohypophyseal hormones and catecholamines. Tissue- and hormone-dependent variations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372222"}
{"pmid": "4372224", "title": "Solubilization and purification of a prolactin receptor from the rabbit mammary gland.", "content": "Solubilization and purification of a prolactin receptor from the rabbit mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372224"}
{"pmid": "4372223", "title": "Studies on receptor-mediated activation of adenylyl cyclases. V. Transient kinetics of the activation of beef renal medullary adenylyl cyclase by neurohypophyseal hormones: estimation of apparent rate constants of the receptor-hormone interaction.", "content": "Studies on receptor-mediated activation of adenylyl cyclases. V. Transient kinetics of the activation of beef renal medullary adenylyl cyclase by neurohypophyseal hormones: estimation of apparent rate constants of the receptor-hormone interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372223"}
{"pmid": "4372225", "title": "Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. I. Purification and molecular properties.", "content": "Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. I. Purification and molecular properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372225"}
{"pmid": "4372226", "title": "Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. II. Selective chemical reactivity of amino and sulfhydryl groups.", "content": "Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. II. Selective chemical reactivity of amino and sulfhydryl groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372226"}
{"pmid": "4372227", "title": "Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. III. Isolation and sequences of peptides containing selectively labeled lysine and cysteine residues.", "content": "Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. III. Isolation and sequences of peptides containing selectively labeled lysine and cysteine residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372227"}
{"pmid": "4372228", "title": "Physicochemical properties of the diphosphopyridine nucleotide-specific isocitrate dehydrogenase of pig heart.", "content": "Physicochemical properties of the diphosphopyridine nucleotide-specific isocitrate dehydrogenase of pig heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372228"}
{"pmid": "4372229", "title": "Gonadotropin receptors in rat testes. Interaction of an ethanol-soluble testicular factor with human follicle-stimulating hormone and luteinizing hormone.", "content": "Gonadotropin receptors in rat testes. Interaction of an ethanol-soluble testicular factor with human follicle-stimulating hormone and luteinizing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372229"}
{"pmid": "4372232", "title": "Some variables in the plaque assay of poliovirus.", "content": "Some variables in the plaque assay of poliovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372232"}
{"pmid": "4372231", "title": "Stability of DTP vaccine.", "content": "Stability of DTP vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372231"}
{"pmid": "4372234", "title": "Purification and some properties of formate dehydrogenase.", "content": "Purification and some properties of formate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372234"}
{"pmid": "4372235", "title": "Cytochrome c-552 and cytochrome c-554 derived from Nitrosomonas europaea. Purification, properties, and their function in hydroxylamine oxidation.", "content": "Cytochrome c-552 and cytochrome c-554 derived from Nitrosomonas europaea. Purification, properties, and their function in hydroxylamine oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372235"}
{"pmid": "4372236", "title": "Pyrophosphatidic acid. A new phospholipid from cryptococcus neoformans.", "content": "Pyrophosphatidic acid. A new phospholipid from cryptococcus neoformans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372236"}
{"pmid": "4372237", "title": "Effect of glucose and adenosine 3', 5'-cyclic monophosphate on the early development of Dictyostelium discoideum.", "content": "Effect of glucose and adenosine 3', 5'-cyclic monophosphate on the early development of Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372237"}
{"pmid": "4372238", "title": "Studies on lipolysis in lipid micelles isolated from adipose tissue.", "content": "Studies on lipolysis in lipid micelles isolated from adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372238"}
{"pmid": "4372239", "title": "Studies on ESR spectra of chromatophores from Rhodospirillum rubrum.", "content": "Studies on ESR spectra of chromatophores from Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372239"}
{"pmid": "4372240", "title": "Characterization of the external proteins of hamster fibroblasts.", "content": "Characterization of the external proteins of hamster fibroblasts. The results of metabolic labeling studies and enzymatic treatments followed by analysis on polyacrylamide gels show that the external proteins of hamster fibroblast cell lines, which have been identified by lactoperoxidase-catalyzed iodination, do not contain sulphated mucopolysaccharides or hyaluronic acid and are probably unrelated to collagen. Several of the iodinated species comigrate with carbohydrate-containing molecules. In particular, the major iodine-labeled polypeptide of normal fibroblasts appears to be a glycoprotein. This glycoprotein is absent or much reduced in virus-transformed cells, as detected both by iodination and by metabolic labeling. We conclude that the major iodinated polypeptide is not detected on transformed cells because it is absent rather than because it is masked. Approximate molecular weights of the external proteins are also reported.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372240"}
{"pmid": "4372241", "title": "Erythrophagocytosis by the epithelial cells of the bladder.", "content": "Erythrophagocytosis by the epithelial cells of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372241"}
{"pmid": "4372242", "title": "Influence of alkalinity in thin-layer chromatography systems for the separation of impurities in chlorpromazine, promazine and promethazine.", "content": "Influence of alkalinity in thin-layer chromatography systems for the separation of impurities in chlorpromazine, promazine and promethazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372242"}
{"pmid": "4372243", "title": "Pseudohypoaldosteronism: persistence of hyperaldosteronism and evidence for renal tubular and intestinal responsiveness to endogenous aldosterone.", "content": "Pseudohypoaldosteronism: persistence of hyperaldosteronism and evidence for renal tubular and intestinal responsiveness to endogenous aldosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372243"}
{"pmid": "4372244", "title": "The metabolism of vitamin D3 and 25-hydroxyvitamin D3 in normal and anephric humans.", "content": "The metabolism of vitamin D3 and 25-hydroxyvitamin D3 in normal and anephric humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372244"}
{"pmid": "4372245", "title": "Plasma 17-hydroxyprogesterone, 21-deoxycortisol and cortisol in congenital adrenal hyperplasia.", "content": "Plasma 17-hydroxyprogesterone, 21-deoxycortisol and cortisol in congenital adrenal hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372245"}
{"pmid": "4372247", "title": "Severe osteopenia in young adults associated with Cushing's syndrome due to micronodular adrenal disease.", "content": "Severe osteopenia in young adults associated with Cushing's syndrome due to micronodular adrenal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372247"}
{"pmid": "4372246", "title": "Embolization of a mediastinal parathyroid adenoma.", "content": "Embolization of a mediastinal parathyroid adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372246"}
{"pmid": "4372248", "title": "Receptor binding properties of 125I-hFSH prepared by enzymatic iodination.", "content": "Receptor binding properties of 125I-hFSH prepared by enzymatic iodination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372248"}
{"pmid": "4372249", "title": "Sleep EEG stages and plasma growth hormone concentration in states of endogenous and exogenous hypercortisolemia or ACTH elevation.", "content": "Sleep EEG stages and plasma growth hormone concentration in states of endogenous and exogenous hypercortisolemia or ACTH elevation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372249"}
{"pmid": "4372250", "title": "Profile of circulating vasoactive substances in hemorrhagic shock and their pharmacologic manipulation.", "content": "Profile of circulating vasoactive substances in hemorrhagic shock and their pharmacologic manipulation. (a) Hemorrhage in dogs (to 45-50 mm Hg) was associated with a 10-fold increase in plasma renin activity (PRA) which remained elevated throughout the time-course of shock including the irreversible (decompensation) stage. The presence of angiotensin II (AII) in arterial blood was demonstrated by the bloodbathed organ technique and confirmed by blockade with specific AII antagonists (cysteine(8)-AII or isoleucine(8)-AII). The contribution of AII to systemic peripheral resistance during hemorrhage shock in dogs was established by administering AII antagonists which immediately cause a further fall in blood pressure.(b) Plasma catecholamines (CA) steadily increased during hemorrhage and peaked during compensation (a 100-fold increase). The CA decreased progressively during decompensation.(c) Prostaglandin (PG) E-like material was observed in arterial blood for 15-60 min (after hemorrhage); the peak arterial concentration was 2.6 ng/ml blood. Indomethacin (i.v., before 80% of maximum bleedout): (i) confirmed the presence of PGE, (ii) increased blood pressure, and (iii) increased blood loss.(d) Thus: peripheral resistance during hemorrhagic shock seems temporally correlated with blood CA levels (and not PRA), and the renin-AII system contributes to the maintenance of vascular resistance and may markedly decrease perfusion of organs, such as kidney; the administration of the proper combination of specific antagonists of vasoconstrictor humoral substances may radically improve organ perfusion and could contribute to ultimate recovery from hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372250"}
{"pmid": "4372251", "title": "Thyroid hormone action: in vitro characterization of solubilized nuclear receptors from rat liver and cultured GH1 cells.", "content": "Thyroid hormone action: in vitro characterization of solubilized nuclear receptors from rat liver and cultured GH1 cells. We previously reported that putative nuclear receptors for thyroid hormone can be demonstrated by incubation of hormone either with intact GH(1) cells, a rat pituitary tumor cell line, or with isolated GH(1) cell nuclei and rat liver nuclei in vitro. We characterized further the kinetics of triiodothyronine (T3) and thyroxine (T4) binding and the biochemical properties of the nuclear receptor after extraction to a soluble form with 0.4 M KCl. In vitro binding of [(125)I]T3 and [(125)I]T4 with GH(1) cell and rat liver nuclear extract was examined at 0 degrees C and 37 degrees C. Equilibrium was attained within 5 min at 37 degrees C and 2 h at 0 degrees C. The binding activity from GH(1) cells was stable for at least 1 h at 37 degrees C and 10 days at - 20 degrees C. Chromatography on a weak carboxylic acid column and inactivation by trypsin and Pronase, but not by DNase or RNase, suggested that the putative receptor was a nonhistone protein. The estimated equilibrium dissociation constants (K(d)) for hormone binding to the solubilized nuclear binding activity was 1.80 x 10(-10) M (T3) and 1.20 x 10(-9) M (T4) for GH(1) cells and 1.57 x 10(-10) M (T3) and 2.0 x 10(-9) M (T4) for rat liver. These K(d) values for T3 are virtually identical to those which we previously reported with isolated rat liver nuclei and GH(1) cell nuclei in vitro. The 10-fold greater affinity for T3 compared to T4 in the nuclear extract is also identical to that observed with intact GH(1) cells. In addition, the [(125)I]T3 and [(125)I]T4 high-affinity binding in the nuclear extract were inhibited by either nonradioactive T3 or T4, which suggests that the binding activity in nuclear extract was identical for T3 and T4. In contrast, the binding activity for T4 and T3 in GH(1) cell cytosol was markedly different from that observed with nuclear extract (K(d) values were 2.87 x 10(-10) M for T4 and 1.13 x 10(-9) M for T3). Our results indicate that nuclear receptors for T3 and T4 can be isolated in a soluble and stable form with no apparent change in hormonal affinity. This should allow elucidation of the mechanisms of thyroid hormone action at the molecular level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372251"}
{"pmid": "4372252", "title": "Hereditary hemolytic anemia with human erythrocyte pyrimidine 5'-nucleotidase deficiency.", "content": "Hereditary hemolytic anemia with human erythrocyte pyrimidine 5'-nucleotidase deficiency. A severe deficiency of a red cell pyrimidine 5'-nucleotidase was found to be associated with hereditary hemolytic anemia in four members of three kindreds. The syndrome was characterized by marked increases above normal in red cell basophilic stippling, total nucleotides, and GSH and by a fairly severe deficiency of ribosephosphate pyrophosphokinase (EC 2.7.6.1.). Patient erythrocytes uniquely contained large amounts of pyrimidine 5'-ribonucleotides. In earlier studies, these were erroneously considered to be adenosine phosphates, since all previous investigations of the nucleotides of human red cells and reticulocytes have shown 97% or more to contain adenine. Total nucleotides in patient cells were present in amounts 3-6 times greater than normal, and approximately 80% contained pyrimidine. The ultraviolet spectral curves of deproteinized red cell extracts exhibited a shift in maximum absorbance from the usual 256-257 nm to approximately 266-270 nm, and absorbance at 250, 270, 280, and 290 nm, expressed as a ratio of that at 260 nm, differed greatly from normal. The spectral characteristics of extracts provide the basis of a readily performed screening procedure, which does not require enzyme assay. The nucleotidase activity in deficient red cells assayed less than 14%, and usually less than 10%, of normal and much less in terms of reticulocyte-rich blood, where it was consistently found to be increased. The enzyme has a pH optimum of 7.5-8.0, is inhibited by EDTA, and does not utilize purine 5'-ribonucleotides or beta-glycerophosphate as substrates. While comparatively few family members have been available thus far for study, initial data are compatible with an autosomal, recessive mode of transmission of the deficiency. The pyrimidine 5'-ribonucleotides are presumably derived from RNA degradation and, not being diffusible, accumulate when the enzyme catalyzing their dephosphorylation is deficient. It is postulated that the prominent basophilic stippling results from retarded ribosomal RNA degradation secondary to accumulation of degradation products, namely pyrimidine 5'-ribonucleotides. Ribosephosphate pyrophosphokinase deficiency is considered to be an epiphenomenon. The mechanism responsible for increased red cell GSH is unknown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372252"}
{"pmid": "4372254", "title": "Contribution of the fatty acids of three low density serum lipoproteins to bovine milk fat.", "content": "Contribution of the fatty acids of three low density serum lipoproteins to bovine milk fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372254"}
{"pmid": "4372253", "title": "A light and electron microscopic study of the liver in case of erythrohepatic protoporphyria and in griseofulvin-induced porphyria in mice.", "content": "A light and electron microscopic study of the liver in case of erythrohepatic protoporphyria and in griseofulvin-induced porphyria in mice. The light- and electron-microscopic appearances of a liver biopsy from a case of erythrohepatic protoporphyria are compared with the appearances of the liver in griseofulvin-induced porphyria in mice. Crystals are present in hepatocytes and in the bile secretory pathways in each case. The nature and significance of these is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372253"}
{"pmid": "4372255", "title": "Hereditary bovine syndactyly. II. Hyperthermia.", "content": "Hereditary bovine syndactyly. II. Hyperthermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372255"}
{"pmid": "4372256", "title": "A test of the salience hypothesis of dream recall.", "content": "A test of the salience hypothesis of dream recall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372256"}
{"pmid": "4372261", "title": "Simulation of the effect of recruitment on loudness relationships in speech.", "content": "Simulation of the effect of recruitment on loudness relationships in speech.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372261"}
{"pmid": "4372265", "title": "Electron spin resonance spectroscopy of single crystals of concanavalin A.", "content": "Electron spin resonance spectroscopy of single crystals of concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372265"}
{"pmid": "4372257", "title": "Reactions in glass ionomer cements: II. An infrared spectroscopic study.", "content": "Reactions in glass ionomer cements: II. An infrared spectroscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372257"}
{"pmid": "4372259", "title": "Collagenolytic activity of human gingival crevice fluid.", "content": "Collagenolytic activity of human gingival crevice fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372259"}
{"pmid": "4372266", "title": "Electron spin resonance spectroscopy of aqueous solutions of concanavalin A.", "content": "Electron spin resonance spectroscopy of aqueous solutions of concanavalin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372266"}
{"pmid": "4372267", "title": "Sensitivity of human diploid embryonic lung cells for isolation of ECHO viruses from sewage.", "content": "Sensitivity of human diploid embryonic lung cells for isolation of ECHO viruses from sewage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372267"}
{"pmid": "4372268", "title": "Myxovirus parainfluenzae type 4 A growth in monkey-kidney tissue cultures and respiratory epithelium of experimentally infected hamsters.", "content": "Myxovirus parainfluenzae type 4 A growth in monkey-kidney tissue cultures and respiratory epithelium of experimentally infected hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372268"}
{"pmid": "4372269", "title": "Maintenance of latent herpetic infection: an apparent role for anti-viral IgG.", "content": "Maintenance of latent herpetic infection: an apparent role for anti-viral IgG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372269"}
{"pmid": "4372270", "title": "Modulation of polymorphonuclear leukocyte-mediated antibody-dependent cellular cytotoxicity.", "content": "Modulation of polymorphonuclear leukocyte-mediated antibody-dependent cellular cytotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372270"}
{"pmid": "4372258", "title": "Induced collagenolytic activity by electrical stimulation of embryonic fibroblasts in tissue culture.", "content": "Induced collagenolytic activity by electrical stimulation of embryonic fibroblasts in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372258"}
{"pmid": "4372260", "title": "Potassium dependent phosphatase in mitochondria of rat submandibular gland.", "content": "Potassium dependent phosphatase in mitochondria of rat submandibular gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372260"}
{"pmid": "4372271", "title": "Relative insensitivity of spleen cells to interferon.", "content": "Relative insensitivity of spleen cells to interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372271"}
{"pmid": "4372263", "title": "Effects of processing on the amine content of pork bellies.", "content": "Effects of processing on the amine content of pork bellies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372263"}
{"pmid": "4372272", "title": "Susceptibility tests of anaerobic bacteria: statistical and clinical considerations.", "content": "Susceptibility tests of anaerobic bacteria: statistical and clinical considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372272"}
{"pmid": "4372273", "title": "Cyclophosphamide-potentiated West Nile viral encephalitis: relative influence of cellular and humoral factors.", "content": "Cyclophosphamide-potentiated West Nile viral encephalitis: relative influence of cellular and humoral factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372273"}
{"pmid": "4372264", "title": "Photodecomposition of mirex on silica gel chromatoplates exposed to natural and artificial light.", "content": "Photodecomposition of mirex on silica gel chromatoplates exposed to natural and artificial light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372264"}
{"pmid": "4372274", "title": "A comparison of two methods of gentamicin assay: an enzymatic procedure and an agar diffusion technique.", "content": "A comparison of two methods of gentamicin assay: an enzymatic procedure and an agar diffusion technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372274"}
{"pmid": "4372275", "title": "Serologic response to varicella-zoster membrane antigens measured by direct immunofluorescence.", "content": "Serologic response to varicella-zoster membrane antigens measured by direct immunofluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372275"}
{"pmid": "4372276", "title": "Cytosine arabinoside for localized herpes zoster in patients with cancer: failure in a controlled trial.", "content": "Cytosine arabinoside for localized herpes zoster in patients with cancer: failure in a controlled trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372276"}
{"pmid": "4372262", "title": "Implication of mycotoxins for human health.", "content": "Implication of mycotoxins for human health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372262"}
{"pmid": "4372277", "title": "Workshop on hospital-associated infections.", "content": "Workshop on hospital-associated infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372277"}
{"pmid": "4372278", "title": "Influenza research in the Soviet Union--1974.", "content": "Influenza research in the Soviet Union--1974.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372278"}
{"pmid": "4372279", "title": "Letter: Severe combined nephrotoxicity of BL-P1654 and gentamicin.", "content": "Letter: Severe combined nephrotoxicity of BL-P1654 and gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372279"}
{"pmid": "4372283", "title": "A hepatocarcinoma with osseous metastases.", "content": "A hepatocarcinoma with osseous metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372283"}
{"pmid": "4372284", "title": "Lipoproteins in a nonrecirculating perfusate of rat liver.", "content": "Lipoproteins in a nonrecirculating perfusate of rat liver. Rat livers were perfused in a nonrecirculating system for 30-40 min with Krebs-Ringer bicarbonate-0.1% glucose solution gassed with 95% O(2)-5% CO(2) at 37 degrees C at a flow rate of 3 ml/g/min. The livers appeared normal as judged by O(2) uptake, bile flow, transaminase release, and net protein output (2.5 mg/g/hr). The perfusate was concentrated by ultrafiltration using Amicon PM-10 or PM-30 membranes. The concentrated perfusate was subjected to sequential ultracentrifugation at solution densities of 1.006, 1.04, 1.06, and 1.21, and the top fractions were analyzed for protein and lipid. The net release of protein in the four density classes, suitably corrected, averaged 39, 10, 5, and 20 micro g/g/hr. The lipid composition of the perfusate lipoprotein fractions differed from that of serum mainly in the high percentage of free cholesterol, reflecting the lack of exposure to lecithin:cholesterol acyltransferase. When rat serum was fractionated in the same way, most of the lipoprotein in the d 1.006-1.06 range had a density greater than 1.04. It was concluded from these experiments that the liver secretes very low density lipoprotein (VLDL), high density lipoprotein (HDL), and a modified form of VLDL containing less lipid. Comparison of secretion rates and serum lipoprotein levels leads to the conclusion that the latter are largely determined by catabolic rates. When labeled amino acids were present, the perfusate HDL had a higher specific activity than VLDL. Addition of carrier whole serum did not alter recovery of labeled lipoproteins, but when these were isolated from Golgi membranes after a 40-min perfusion, more than twice as much label was recovered in HDL, suggesting the presence of precursors within the Golgi. The main advantages of the nonrecirculation perfusion technique are the avoidance of catabolic reactions, simplicity, and complete control over the composition of the perfusing medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372284"}
{"pmid": "4372285", "title": "Subcellular localization of hexadecanedioic acid activation in human liver.", "content": "Subcellular localization of hexadecanedioic acid activation in human liver. The activation of hexadecanedioic acid has been studied in subcellular fractions of human liver. The activation capacity in a total homogenate of human liver was found to be 0.5 micro mole/min/g wet wt of tissue, about 10% of that for palmitic acid. Hexadecanedioic acid was activated by the mitochondrial and microsomal fractions. The mitochondrial enzyme is probably localized outside the inner mitochondrial compartment. The subcellular distribution of the hexadecanedioic acid activation was almost identical with the distribution of palmitic acid activation. Hexadecanedioic and palmitic acids seemed to compete for the same enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372285"}
{"pmid": "4372286", "title": "Stimulation of erythroblast maturation in vitro by sphingolipids.", "content": "Stimulation of erythroblast maturation in vitro by sphingolipids. A lipid factor previously isolated from leukocytes and found to stimulate basophilic erythroblast formation in an in vitro system of incubated rabbit bone marrow cells has been analyzed by thin-layer chromatography, gas-liquid chromatography, and gas-liquid chromatography-mass spectrometry. The biologically active components are sphingosine ceramides of tetracosanoic and dehydrotetracosanoic acids. Tests of a series of related ceramides show a high degree of structural specificity for the C(24)-V-acyl compounds with significant but markedly lower activity of the C(22) analog. Commercially available sphingomyelin shows activity comparable to that of the tetracosanoic acid ceramide. Sphingosine and tetracosanic acid supplied in equimolar amounts have negligible activity. The results, in the context of other findings, suggest a possible supportive role of plasma ceramides and sphingomyelins in red cell maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372286"}
{"pmid": "4372287", "title": "Influx of cholesterol into plasma in rabbits with fasting hyperbetalipoproteinemia.", "content": "Influx of cholesterol into plasma in rabbits with fasting hyperbetalipoproteinemia. New Zealand white rabbits exhibited as much as a threefold increase in plasma cholesterol but no change in hepatic cholesterol when fasted for 7-9 days. Agarose electrophoresis and ultracentrifugation of plasma samples showed that only low density lipoprotein increased during fasting. Fasting changed the composition of the low density lipoprotein by increasing the percentage of cholesterol and decreasing the percentage of triglyceride while protein and phospholipid remained the same. Rates of cholesterol secretion into plasma, measured by Triton WR 1339 injection, and rates of plasma cholesteryl ester synthesis, determined by [2-(14)C]mevalonate injection, were similar for fed and fasted rabbits. These findings suggest that fasting hypercholesterolemia in rabbits did not result from increased production of low density lipoproteins. Triton WR 1339 was shown to inhibit plasma cholesterol esterification in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372287"}
{"pmid": "4372289", "title": "Analysis of alpha-lipoprotein cholesterol in 50 microl of plasma.", "content": "Analysis of alpha-lipoprotein cholesterol in 50 microl of plasma. A micromethod for quantitation of alpha-lipoprotein cholesterol was devised for gas-liquid chromatography to minimize plasma sample size and facilitate lipid studies using capillary blood from children or small animals. alpha-Lipoprotein cholesterol was measured by gas-liquid chromatography in 20 micro l of the centrifuged supernate obtained after addition of 5 micro l of mixed heparin-manganese chloride solution 1:1 (v/v) to 50 micro l of plasma. Comparison of venous alpha-lipoprotein cholesterol measured by gas-liquid chromatography with venous alpha-lipoprotein cholesterol measured by conventional heparin-manganese precipitation and ferric chloride (colorimetric) cholesterol determination gave a correlation coefficient of 0.98 for 80 plasma samples. Capillary alpha-lipoprotein cholesterol and venous alpha-lipoprotein cholesterol were closely correlated in 31 patients (r = 0.97).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372289"}
{"pmid": "4372288", "title": "Reversible protein kinase activation of hormone-sensitive lipase from chicken adipose tissue.", "content": "Reversible protein kinase activation of hormone-sensitive lipase from chicken adipose tissue. Hormone-sensitive lipase partially purified from adipose tissue of laying hens was markedly activated by cyclic AMP-dependent protein kinase. Activation was approximately 4-fold (ranging up to as great as 10-fold) compared with the much lower degree of activation obtained with analogous preparations from rat and human adipose tissues (59 and 86%, respectively). The partially purified preparations contained adequate endogenous protein kinase activity to effect complete activation with addition of cyclic AMP, ATP, and Mg(2+). Activation was blocked by protein kinase inhibitor (from rabbit skeletal muscle) but could be restored fully by addition of excess exogenous protein kinase (from bovine skeletal muscle). The fully activated lipase was slowly deactivated by dialysis at 4 degrees C and then rapidly and almost fully reactivated by addition of cyclic AMP and ATP-Mg(2+). Reactivation was blocked by protein kinase inhibitor. This deactivation-reactivation cycle was rapid at 23 degrees C with dialysis against charcoal and could be demonstrated repeatedly using a single preparation. The reversible deactivation of protein kinase-activated enzyme is presumed to reflect the action of a lipase phosphatase. Lipase prepared from tissue previously exposed to glucagon yielded a much smaller degree of activation than lipase prepared from tissue not exposed to the lipolytic hormone, indicating that the physiological hormone-induced activation is probably similar to or identical with the protein kinase activation demonstrated in the cell-free preparations. Under the conditions of assay used, the partially purified lipase fraction contained diglyceride, monoglyceride, and lipoprotein lipase activities. However, treatment with cyclic AMP-dependent protein kinase had virtually no effect on these lipase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372288"}
{"pmid": "4372291", "title": "Human T lymphocyte \"E\" rosette function. I. A process modulated by intracellular cyclic AMP.", "content": "Human T lymphocyte \"E\" rosette function. I. A process modulated by intracellular cyclic AMP. The capacity of normal human T lymphocytes to form rosettes with sheep red blood cells can be inhibited by drugs or agents which induce elevations in intracellular levels of cyclic AMP. The effect is early in the presence of agents which elicit rapid elevations in intracellular cyclic AMP (isoproterenol, aminophylline) and occurs later in the presence of cholera toxin which induces a dalayed increase in endogenous cyclic AMP. Dibutyryl cyclic AMP is inhibitory, and the effects of dibutyryl cyclic AMP and the adenyl cyclase stimulators are potentiated by inhibition of phosphodiesterase. These data provide substantial evidence that elevation of intracellular cyclic AMP diminishes E rosette function of lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372291"}
{"pmid": "4372290", "title": "Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia virus.", "content": "Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia virus. This report clearly demonstrates that a systemic lupus erythematosus (SLE)-like syndrome and lymphoma can be induced in immunologically normal (BALB/c x NZB)F(1) mice by infection of neonates with a murine leukemia virus (MuLV) (Scripps leukemia virus [SLV] 60A) isolated from NZB lymphoblasts. SLV 60A was titered in vitro (XC test) and administered to newborn and adult (BALB/c x NZB)F(1) mice over six log(10) dilutions. Propagation of MuLV in the newborn recipients was indicated by greatly elevated serum Mu gs-1 levels which were proportional to the dose of virus given. The SLE-like syndrome was characterized by antinuclear antibodies (ANA) and immune complex-type glomerulonephritis. ANA production was related to the dose of virus and reached the highest levels at 8-16 wk. The incidence of glomerulonephritis was also correlated with the dose of virus and reached nearly 50% in the animals given the highest virus dose. Both titers of ANA and incidence of glomerulonephritis were greater in females than in males, although the amounts of Mu gs-1 in sera of both sexes were equal. The incidence of direct Coombs' positivity was not significantly affected by inoculation of this virus. The incidence and time of onset of thymocytic lymphoma were linearly related to the amount of virus inoculated. High serum Mu gs-1 levels predicted lymphoma development and reflected increases in the amount of infectious virus in the spleen. No induction of tumors, autoimmunity, or high serum Mu gs-1 levels followed administration of SLV 60A to 6-wk old (BALB/c x NZB)F(1) mice or inactivated 60A or active AKR virus to newborns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372290"}
{"pmid": "4372293", "title": "Distribution of fibroblast surface antigen: association with fibrillar structures of normal cells and loss upon viral transformation.", "content": "Distribution of fibroblast surface antigen: association with fibrillar structures of normal cells and loss upon viral transformation. The localization of a cell type-specific, soluble fibroblast surface antigen (SFA) was studied by immunofluorescence and by scanning electron microscopy of the same cells. The antigen had an uneven distribution forming streaks on chick embryo fibroblasts. It was localized to membrane processes and ridges, with a diameter of 50-200 nm. The processes extended from the periphery of the cells to the substratum or to other cells. Trypsin treatment completely removed detectable amounts of SFA. The antigen was detectable within 1 h after trypsin-treated cells were reseeded. The reappearance of SFA correlated with the restoration of membrane processes. Fibroblasts transformed by Rous sarcoma virus (RSV) showed loss of all or most SFA. When normal cells were transformed without subcultivation and trypsinization a fibrillar extracellular network of SFA remained under the transformed fibroblasts while the cells themselves were negative in immunofluorescence. When fibroblasts infected by RSV mutants were transferred to nonpermissive temperature for transformation new SFA was detected within 2 h. These data lead us to propose that loss of stabilizing and anchoring effect of SFA molecules in fibrillar cell surface structures may be critical in altered growth control and malignant transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372293"}
{"pmid": "4372292", "title": "Stimulation by endocytosis of the secretion of collagenase and neutral proteinase from rabbit synovial fibroblasts.", "content": "Stimulation by endocytosis of the secretion of collagenase and neutral proteinase from rabbit synovial fibroblasts. Rabbit synovial fibroblasts in monolayer culture secrete a specific collagenase and a neutral endopeptidase into their serum-free culture medium. The rate of secretion of these two enzymes is increased after the ingestion and storage of latex particles within the vacuolar system of the cells. The increased rates of secretion of the neutral enzymes are stable for over 2 wk in the absence of a further phagocytic bout. In constrast there is little change in the extracellular levels of two lysosomal hydrolases, cathepsin D and beta-glucuronidase. The increase in the secretory rates for the two neutral enzymes is related to the number of latex particles ingested by the cells, and increases of up to 12-fold over the nonphagocytosing cultures were observed. A variety of other materials including mycostatin particles and dextran sulfate also induced increases in the secretion of collagenase. These results are discussed in relation to the turnover of connective tissue matrix macromolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372292"}
{"pmid": "4372294", "title": "Active transport of amino acids by membrane vesicles of Thiobacillus neapolitanus.", "content": "Active transport of amino acids by membrane vesicles of Thiobacillus neapolitanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372294"}
{"pmid": "4372295", "title": "Identification of intracellular polysaccharide granules in thin sections of Nocardia asteroides.", "content": "Identification of intracellular polysaccharide granules in thin sections of Nocardia asteroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372295"}
{"pmid": "4372297", "title": "DNA synthesis in resting African green monkey kidney cells infected with defective SV 40.", "content": "DNA synthesis in resting African green monkey kidney cells infected with defective SV 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372297"}
{"pmid": "4372296", "title": "The properties of the Sendai virus ribonucleoproteins involved in genome transcription in infected cells.", "content": "The properties of the Sendai virus ribonucleoproteins involved in genome transcription in infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372296"}
{"pmid": "4372298", "title": "Structural phosphoproteins associated with ten rhabdoviruses.", "content": "Structural phosphoproteins associated with ten rhabdoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372298"}
{"pmid": "4372299", "title": "Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.", "content": "Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372299"}
{"pmid": "4372300", "title": "Biochemical studies on the herpes simplex virus-specified deoxypyrimidine kinase activity.", "content": "Biochemical studies on the herpes simplex virus-specified deoxypyrimidine kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372300"}
{"pmid": "4372301", "title": "Cell interaction with poly(rI)-poly(rC) and interferon induction in chick and mouse cells.", "content": "Cell interaction with poly(rI)-poly(rC) and interferon induction in chick and mouse cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372301"}
{"pmid": "4372302", "title": "A possible precursor containing RNA of a bovine enterovirus: the provirion 11.", "content": "A possible precursor containing RNA of a bovine enterovirus: the provirion 11.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372302"}
{"pmid": "4372304", "title": "Renaturation of inactivated interferons: requirement for reduction of a major component; lack of requirement for reduction of a minor component.", "content": "Renaturation of inactivated interferons: requirement for reduction of a major component; lack of requirement for reduction of a minor component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372304"}
{"pmid": "4372303", "title": "The iodination of bovine enterovirus particles.", "content": "The iodination of bovine enterovirus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372303"}
{"pmid": "4372305", "title": "Translation of virus mRNA: protein synthesis directed by several virus RNAs in a cell-free extract from wheat germ.", "content": "Translation of virus mRNA: protein synthesis directed by several virus RNAs in a cell-free extract from wheat germ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372305"}
{"pmid": "4372306", "title": "Cell fusion by HeLa cells persistently infected with haemadsorption type 2 virus.", "content": "Cell fusion by HeLa cells persistently infected with haemadsorption type 2 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372306"}
{"pmid": "4372308", "title": "Location of the origin and terminus of replication in polyoma virus DNA.", "content": "Location of the origin and terminus of replication in polyoma virus DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372308"}
{"pmid": "4372307", "title": "Absence of glycoproteins in poliovirus particles.", "content": "Absence of glycoproteins in poliovirus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372307"}
{"pmid": "4372309", "title": "Interferon-sepharose: priming of L cells for induction of interferon by MM virus.", "content": "Interferon-sepharose: priming of L cells for induction of interferon by MM virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372309"}
{"pmid": "4372310", "title": "Enhanced production of human interferon by u.v. irradiated cells.", "content": "Enhanced production of human interferon by u.v. irradiated cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372310"}
{"pmid": "4372311", "title": "Focal necrotic hepatitis in mice as a biological marker for differentiation of Herpesvirus hominis type 1 and type 2.", "content": "Focal necrotic hepatitis in mice as a biological marker for differentiation of Herpesvirus hominis type 1 and type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372311"}
{"pmid": "4372312", "title": "Dependence of RNA replication on continuous protein synthesis in a temperature-sensitive mutant of foot-and-mouth disease virus.", "content": "Dependence of RNA replication on continuous protein synthesis in a temperature-sensitive mutant of foot-and-mouth disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372312"}
{"pmid": "4372313", "title": "Comparative production of paramyxoviruses by avian heart cells.", "content": "Comparative production of paramyxoviruses by avian heart cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372313"}
{"pmid": "4372314", "title": "Demonstration of a receptor for IgG in Syrian hamster cells transformed with herpes simplex virus.", "content": "Demonstration of a receptor for IgG in Syrian hamster cells transformed with herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372314"}
{"pmid": "4372315", "title": "Immunofluorescent studies of RD-114 virus replication in cell culture.", "content": "Immunofluorescent studies of RD-114 virus replication in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372315"}
{"pmid": "4372317", "title": "Infectivity of mengovirus replicative form. Relationship to cellular transcription.", "content": "Infectivity of mengovirus replicative form. Relationship to cellular transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372317"}
{"pmid": "4372316", "title": "Replication of simian virus 40 in permissive cells: assembly of virus components.", "content": "Replication of simian virus 40 in permissive cells: assembly of virus components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372316"}
{"pmid": "4372318", "title": "Isolation of herpes simplex virus DNA from virus particles and infected cells by electrophoresis in polyacrylamide gels.", "content": "Isolation of herpes simplex virus DNA from virus particles and infected cells by electrophoresis in polyacrylamide gels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372318"}
{"pmid": "4372319", "title": "Sequential steps in attachment of human rhinovirus type 2 to HeLa cells.", "content": "Sequential steps in attachment of human rhinovirus type 2 to HeLa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372319"}
{"pmid": "4372320", "title": "Electron microscopic studies of visna virus ribonucleic acid.", "content": "Electron microscopic studies of visna virus ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372320"}
{"pmid": "4372322", "title": "Myelin proteins from different regions of the central nervous system.", "content": "Myelin proteins from different regions of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372322"}
{"pmid": "4372321", "title": "Phospholipid metabolism in experimental allergic encephalomyelitis: activity of mitochondrial phospholipase A2 of rat brain towards specifically labelled 1,2-diacyl-, 1-alk-1'-enyl-2-acyl- and 1-alkyl-2-acyl-sn-glycero-3-phosphorylcholine.", "content": "Phospholipid metabolism in experimental allergic encephalomyelitis: activity of mitochondrial phospholipase A2 of rat brain towards specifically labelled 1,2-diacyl-, 1-alk-1'-enyl-2-acyl- and 1-alkyl-2-acyl-sn-glycero-3-phosphorylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372321"}
{"pmid": "4372323", "title": "In vitro Ca2+ dependent proteolysis in brain tissues: a possible source of error in transmitter metabolism studies.", "content": "In vitro Ca2+ dependent proteolysis in brain tissues: a possible source of error in transmitter metabolism studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372323"}
{"pmid": "4372325", "title": "Na+-K+-activated ATPase and K+-activated p-nitrophenylphosphatase activities: a comparison of their regional localizations in the C57 mouse brain.", "content": "Na+-K+-activated ATPase and K+-activated p-nitrophenylphosphatase activities: a comparison of their regional localizations in the C57 mouse brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372325"}
{"pmid": "4372326", "title": "Plasma renin and angiotensin II levels in subarachnoid haemorrhage.", "content": "Plasma renin and angiotensin II levels in subarachnoid haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372326"}
{"pmid": "4372324", "title": "Cyclic nucleotide hydrolysis: some possible natural regulators in retina and rod outer segments.", "content": "Cyclic nucleotide hydrolysis: some possible natural regulators in retina and rod outer segments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372324"}
{"pmid": "4372327", "title": "Labeled asialo-human chorionic gonadotropin as a liver-scanning agent.", "content": "Labeled asialo-human chorionic gonadotropin as a liver-scanning agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372327"}
{"pmid": "4372328", "title": "Preoperative localization of an insulinoma by external scanning with 131I-toluidine blue.", "content": "Preoperative localization of an insulinoma by external scanning with 131I-toluidine blue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372328"}
{"pmid": "4372329", "title": "Letter: Improving the 99mTc-phosphate bone scan.", "content": "Letter: Improving the 99mTc-phosphate bone scan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372329"}
{"pmid": "4372331", "title": "Extreme dysplasia in renal epithelium of a young woman dying from hepatocarcinoma.", "content": "Extreme dysplasia in renal epithelium of a young woman dying from hepatocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372331"}
{"pmid": "4372330", "title": "Effect of cellulose and cholesterol on blood and yolk lipids and reproductive efficiency of the hen.", "content": "Effect of cellulose and cholesterol on blood and yolk lipids and reproductive efficiency of the hen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372330"}
{"pmid": "4372332", "title": "Characterisation of spontaneous and induced epithelial and mesenchymal tumours by their enzyme patterns.", "content": "Characterisation of spontaneous and induced epithelial and mesenchymal tumours by their enzyme patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372332"}
{"pmid": "4372333", "title": "Origin of osmophilic inclusion bodies in type II pneumocytes.", "content": "Origin of osmophilic inclusion bodies in type II pneumocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372333"}
{"pmid": "4372335", "title": "Mesenchymal renal neoplasms of infancy revisited.", "content": "Mesenchymal renal neoplasms of infancy revisited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372335"}
{"pmid": "4372336", "title": "Calcified hepatoblastoma in a newborn.", "content": "Calcified hepatoblastoma in a newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372336"}
{"pmid": "4372334", "title": "Cytological studies on the absorptive surfaces of cestodes. VIII. Phosphohydrolase activity and cation adsorption in the tegument brush border of Hymenolepis diminuta.", "content": "Cytological studies on the absorptive surfaces of cestodes. VIII. Phosphohydrolase activity and cation adsorption in the tegument brush border of Hymenolepis diminuta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372334"}
{"pmid": "4372337", "title": "Critical evaluation of use of effective protein fractions in developing pharmacokinetic models for drug distribution.", "content": "Critical evaluation of use of effective protein fractions in developing pharmacokinetic models for drug distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372337"}
{"pmid": "4372338", "title": "Synthesis and biological evaluation of 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphate.", "content": "Synthesis and biological evaluation of 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372338"}
{"pmid": "4372339", "title": "Release of norepinephrine and dopamine-beta-hydroxylase by nerve stimulation. II. Effects of papaverine.", "content": "Release of norepinephrine and dopamine-beta-hydroxylase by nerve stimulation. II. Effects of papaverine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372339"}
{"pmid": "4372340", "title": "Ontogenesis of adrenergic and cholinergic neuroeffector transmission in chick embryo heart.", "content": "Ontogenesis of adrenergic and cholinergic neuroeffector transmission in chick embryo heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372340"}
{"pmid": "4372341", "title": "Increased sensitivity of sinoatrial pace-maker to acetylcholine and to catecholamines at the onset of autonomic neuroeffector transmission in chick embryo heart.", "content": "Increased sensitivity of sinoatrial pace-maker to acetylcholine and to catecholamines at the onset of autonomic neuroeffector transmission in chick embryo heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372341"}
{"pmid": "4372343", "title": "Luteolysis in normal and prostaglandin F2 alpha-treated pseudopregnant rabbits.", "content": "Luteolysis in normal and prostaglandin F2 alpha-treated pseudopregnant rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372343"}
{"pmid": "4372344", "title": "The arterial migration of trophoblast in the uterus of the golden hamster, Mesocricetus auratus.", "content": "The arterial migration of trophoblast in the uterus of the golden hamster, Mesocricetus auratus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372344"}
{"pmid": "4372345", "title": "Growth hormone responses to hypoglycaemia in women with secondary amenorrhoea.", "content": "Growth hormone responses to hypoglycaemia in women with secondary amenorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372345"}
{"pmid": "4372346", "title": "The stimulation of mouse ovarian follicular growth in vitro by dibutyryl cyclic adenosine 3':5' monophosphate.", "content": "The stimulation of mouse ovarian follicular growth in vitro by dibutyryl cyclic adenosine 3':5' monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372346"}
{"pmid": "4372347", "title": "Current guidelines for the use of antimicrobial agents.", "content": "Current guidelines for the use of antimicrobial agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372347"}
{"pmid": "4372348", "title": "Laboratory aids in the diagnosis of gynecologic infections--progress and pitfalls.", "content": "Laboratory aids in the diagnosis of gynecologic infections--progress and pitfalls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372348"}
{"pmid": "4372349", "title": "Letter: Post-coital estrogen.", "content": "Letter: Post-coital estrogen. The efficacy of Premarin as a postcoital contraceptive agent was eva luated in 194 women.  The patients were instructed to take 4 2.5 mg tablets 3 times a day for 5 days.  There were no pregnancies.  Menses began on the average of 1.1 days before the expected menstrual period, and was not altered by the treatment.  Should the treatment fail to prevent pregnancy, abortion is recommended if desired.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372349"}
{"pmid": "4372350", "title": "Cycloalkanones. 4. Antifertility activity.", "content": "Cycloalkanones. 4. Antifertility activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372350"}
{"pmid": "4372351", "title": "Potential antifertility agents. 6. Synthesis and biological activities of optical isomers of 4 beta-(p-methozyphenyl)-2 beta-methylcyclohexane-alpha-carboxylic acid and related compounds.", "content": "Potential antifertility agents. 6. Synthesis and biological activities of optical isomers of 4 beta-(p-methozyphenyl)-2 beta-methylcyclohexane-alpha-carboxylic acid and related compounds. The optical isomers of the title compound were synthesized and the biological potencies of the two enantiomers were compared.  There was essentially no difference in their hypocholesterolemic activities, as had been predicted, and little or no difference between their uterotropic potencies.  The approximately equal uterotropic activities seen with the enantiomers is explained in terms of stereochemical requirements at the receptor level for an estrogenic response.  A working model of an estrogenic receptor is proposed.  An accompanying paper provides support for the proposed model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372351"}
{"pmid": "4372353", "title": "Congenital limb anomalies:frequency and aetiological factors. Data from the Edinburgh Register of the Newborn (1964-68).", "content": "Congenital limb anomalies:frequency and aetiological factors. Data from the Edinburgh Register of the Newborn (1964-68).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372353"}
{"pmid": "4372352", "title": "Potential antifertility agents. 7. Synthesis and biological activities of 2-,3-, and 6-alkyl-substituted 4-aryl-2-methylcyclohexanecarboxylic acids.", "content": "Potential antifertility agents. 7. Synthesis and biological activities of 2-,3-, and 6-alkyl-substituted 4-aryl-2-methylcyclohexanecarboxylic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372352"}
{"pmid": "4372355", "title": "Haemoglobin H disease and beta-thalassaemia. Clinical haematological and electrophoretic studies in a family from South Lebanon.", "content": "Haemoglobin H disease and beta-thalassaemia. Clinical haematological and electrophoretic studies in a family from South Lebanon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372355"}
{"pmid": "4372354", "title": "Mitochondrial inclusions in fibroblast culture from a patient with beta-methylcrotonylglycinuria.", "content": "Mitochondrial inclusions in fibroblast culture from a patient with beta-methylcrotonylglycinuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372354"}
{"pmid": "4372356", "title": "In vivo synthesis of RNA by vesicular stomatitis virus and its mutants.", "content": "In vivo synthesis of RNA by vesicular stomatitis virus and its mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372356"}
{"pmid": "4372357", "title": "Triplication of a unique genetic segment in a simian virus 40-like virus of human origin and evolution of new viral genomes.", "content": "Triplication of a unique genetic segment in a simian virus 40-like virus of human origin and evolution of new viral genomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372357"}
{"pmid": "4372358", "title": "Characterization of a rearrangement in viral DNA: mapping of the circular simian virus 40-like DNA containing a triplication of a specific one-third of the viral genome.", "content": "Characterization of a rearrangement in viral DNA: mapping of the circular simian virus 40-like DNA containing a triplication of a specific one-third of the viral genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372358"}
{"pmid": "4372359", "title": "Binding of divalent copper ions to aspartic acid residue 52 in hen egg-white lysozyme.", "content": "Binding of divalent copper ions to aspartic acid residue 52 in hen egg-white lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372359"}
{"pmid": "4372360", "title": "An amber dna mutant of Escherichia coli K12 affecting DNA ligase.", "content": "An amber dna mutant of Escherichia coli K12 affecting DNA ligase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372360"}
{"pmid": "4372361", "title": "Phosphorylation of Escherichia coli RNA polymerase by rabbit skeletal muscle protein kinase.", "content": "Phosphorylation of Escherichia coli RNA polymerase by rabbit skeletal muscle protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372361"}
{"pmid": "4372362", "title": "A new class of promoter mutations in the lactose operon of Escherichia coli.", "content": "A new class of promoter mutations in the lactose operon of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372362"}
{"pmid": "4372363", "title": "Transfer RNA genes in mitochondrial DNA of grande (wild-type) yeast.", "content": "Transfer RNA genes in mitochondrial DNA of grande (wild-type) yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372363"}
{"pmid": "4372364", "title": "Oncogenicity of the R-35 rat mammary tumor virus.", "content": "Oncogenicity of the R-35 rat mammary tumor virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372364"}
{"pmid": "4372365", "title": "Prevention of lower limb paralysis by neutralization of type-C RNA virus in wild mice.", "content": "Prevention of lower limb paralysis by neutralization of type-C RNA virus in wild mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372365"}
{"pmid": "4372366", "title": "Comparative pathology of cells transformed by herpes simplex virus type 1 or type 2.", "content": "Comparative pathology of cells transformed by herpes simplex virus type 1 or type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372366"}
{"pmid": "4372367", "title": "Ultrastructural study of herpes simplex virus infection of mouse cells chronically producing Rauscher leukemia virus.", "content": "Ultrastructural study of herpes simplex virus infection of mouse cells chronically producing Rauscher leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372367"}
{"pmid": "4372368", "title": "Protection of mice from malignant tumor implants by enucleated tumor cells.", "content": "Protection of mice from malignant tumor implants by enucleated tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372368"}
{"pmid": "4372369", "title": "Possible gene complementation in in vitro cell lines of Ehrlich ascites tumor established by cell fusion with sendai virus.", "content": "Possible gene complementation in in vitro cell lines of Ehrlich ascites tumor established by cell fusion with sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372369"}
{"pmid": "4372371", "title": "Detection of Epstein-Barr virus-determined intracellular antigens in unfixed cells with labeled antibodies.", "content": "Detection of Epstein-Barr virus-determined intracellular antigens in unfixed cells with labeled antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372371"}
{"pmid": "4372370", "title": "Carcinoembryonic antigen and blood group substances in carcinomas of the stomach and colon.", "content": "Carcinoembryonic antigen and blood group substances in carcinomas of the stomach and colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372370"}
{"pmid": "4372372", "title": "Distribution of virus particles and mammary tumor virus antigens in mouse mammary tumors, transformed BALB-c mouse kidney cells, and GR ascites leukemia cells.", "content": "Distribution of virus particles and mammary tumor virus antigens in mouse mammary tumors, transformed BALB-c mouse kidney cells, and GR ascites leukemia cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372372"}
{"pmid": "4372373", "title": "Histocompatibility genes (the H-2 complex) and susceptibility to mammary tumor virus in mice.", "content": "Histocompatibility genes (the H-2 complex) and susceptibility to mammary tumor virus in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372373"}
{"pmid": "4372374", "title": "Relationship between the cellular and viral antigens of a BALB-c myeloma and murine leukemia virus.", "content": "Relationship between the cellular and viral antigens of a BALB-c myeloma and murine leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372374"}
{"pmid": "4372375", "title": "Antibodies unrelated to Epstein-Barr virus in human sera which precipitate soluble components of cultured lymphoblasts.", "content": "Antibodies unrelated to Epstein-Barr virus in human sera which precipitate soluble components of cultured lymphoblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372375"}
{"pmid": "4372376", "title": "Suppression of the avian sarcoma virus genome in hamster-transformed cells made resistant to 8-azaguanine.", "content": "Suppression of the avian sarcoma virus genome in hamster-transformed cells made resistant to 8-azaguanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372376"}
{"pmid": "4372377", "title": "Quantitative studies on the developing vascular system of rat hepatoma.", "content": "Quantitative studies on the developing vascular system of rat hepatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372377"}
{"pmid": "4372378", "title": "Inhibitory effect of polychlorinated biphenyls on liver tumorigenesis in rats treated with 3'-methyl-4-dimethylaminoazobenzene, n-2-fluorenylacetamide, and diethylnitrosamine.", "content": "Inhibitory effect of polychlorinated biphenyls on liver tumorigenesis in rats treated with 3'-methyl-4-dimethylaminoazobenzene, n-2-fluorenylacetamide, and diethylnitrosamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372378"}
{"pmid": "4372379", "title": "Erythroid hypoplasia in cats inoculated with feline leukemia virus.", "content": "Erythroid hypoplasia in cats inoculated with feline leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372379"}
{"pmid": "4372380", "title": "Bone lesions in cats with anemia induced by feline leukemia virus.", "content": "Bone lesions in cats with anemia induced by feline leukemia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372380"}
{"pmid": "4372381", "title": "Hepatic carcinogenesis of aflatoxin M1 in rainbow trout (Salmo gairdneri) and its enchancement by cyclopropene fatty acids.", "content": "Hepatic carcinogenesis of aflatoxin M1 in rainbow trout (Salmo gairdneri) and its enchancement by cyclopropene fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372381"}
{"pmid": "4372382", "title": "Carcinogenic effects of oral diethylstilbestrol on C3H male mice with and without the mammary tumor virus.", "content": "Carcinogenic effects of oral diethylstilbestrol on C3H male mice with and without the mammary tumor virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372382"}
{"pmid": "4372383", "title": "Further observations on the production of oncornaviruses by MJY-alpha cell line.", "content": "Further observations on the production of oncornaviruses by MJY-alpha cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372383"}
{"pmid": "4372384", "title": "Effect of metabolic inhibitors on killing of tumor cells by antibody and complement.", "content": "Effect of metabolic inhibitors on killing of tumor cells by antibody and complement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372384"}
{"pmid": "4372385", "title": "Changes in growth control and growth requirements associated with neoplastic transformation in vitro.", "content": "Changes in growth control and growth requirements associated with neoplastic transformation in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372385"}
{"pmid": "4372386", "title": "Protein modification, metabolic controls, and their significance in transformation in eukaryotic cells.", "content": "Protein modification, metabolic controls, and their significance in transformation in eukaryotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372386"}
{"pmid": "4372387", "title": "Rhinovirus RNA polymerase: products and kinetics of appearance in human diploid cells.", "content": "Rhinovirus RNA polymerase: products and kinetics of appearance in human diploid cells. The kinetics of appearance of an RNA-dependent RNA polymerase activity obtained from human embryo lung cells infected with rhinovirus type 2 have been followed by analysis of the RNA synthesized by the polymerase preparation in vitro. Little single-stranded RNA was synthesized and the proportion of replicative intermediate to replicative form was over threefold greater than obtained in vivo. The polymerase activity in vivo declined in the presence of cycloheximide showing that continued protein synthesis was necessary to maintain RNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372387"}
{"pmid": "4372389", "title": "Nature of the scrapie agent: evidence against a viroid.", "content": "Nature of the scrapie agent: evidence against a viroid. The postulated viroid nature of scrapie agent was tested. Since the agent could not be recovered after a carefully controlled phenol extraction of infected mouse brains, it is suggested that this agent is not a viroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372389"}
{"pmid": "4372388", "title": "Chromatographic analyses of isoaccepting tRNAs from avian tumor viruses.", "content": "Chromatographic analyses of isoaccepting tRNAs from avian tumor viruses. Low-molecular-weight RNA from transforming viruses (Rous sarcoma virus-Rous-associated virus 1, Schmidt-Ruppin strain of Rous sarcoma virus, and sarcoma-B(77)), from nontransforming viruses (Rous-associated virus 1 and sarcoma-NTB(77)), and from chicken liver, chicken embryo fibroblast, and Rous sarcoma virus-Rous-associated virus 1-transformed chicken embryo fibroblast was isolated and purified. To determine if there are modified, qualitatively or quantitatively different isoaccepting species of tRNA in these avian sarcoma viruses as compared with the cell of virus origin, chicken embryo fibroblast or normal chicken liver, methionyl-, arginyl-, and lysyl-tRNA (with high amino acid acceptance activity), and aspartyl- and glutamyl-tRNA from viral-trans-formed cells (with low viral amino acid acceptance activity) were co-chromatographed on reversed phase-5 chromatography columns, and elution profiles were compared. Although in each case the elution profile between a particular viral and host cell tRNA differed quantitatively, there was no qualitative difference in the profiles of corresponding tRNAs from either transforming or nontransforming viruses examined. Minor quantitative differences in the elution profiles might be a reflection of the metabolic state of the cells, since all evidence points to acceptor activity being of host rather than viral origin. Since, with the exception of selective packaging of methionyl-tRNA (IV) species by both transforming and nontransforming viruses, no selectivity was found for isoacceptor species of other tRNAs, it seems that such preferential packaging of methionyl-tRNA (IV) species has no bearing on the event of viral transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372388"}
{"pmid": "4372390", "title": "Effect of chemically modified 70S RNA from avian myeloblastosis virus (AMV) upon the activity of AMV DNA polymerase.", "content": "Effect of chemically modified 70S RNA from avian myeloblastosis virus (AMV) upon the activity of AMV DNA polymerase. Adenine residues of 70S avian myeloblastosis virus (AMV) RNA are modified when reacted with chloroacetaldehyde. This modification introduces characteristic fluorescent epsilon-adenosine (epsilonA) probes which were used to monitor the reaction. Under suitable conditions, modified 70S(epsilonA) RNA was maintained intact and was inactive as a template for the AMV DNA polymerase. Furthermore, it inhibited the reaction catalyzed by AMV polymerase when 70S RNA was used as template-primer and had no effect on the two tested bacterial polymerases. Protection against the 70S (epsilonA) RNA inhibition was observed when 70S RNA was primed with oligo(dT) indicating preference of the polymerase for the oligo(dT) primed regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372390"}
{"pmid": "4372391", "title": "Infectious rous sarcoma virus and reticuloendotheliosis virus DNAs.", "content": "Infectious rous sarcoma virus and reticuloendotheliosis virus DNAs. An efficient and quantitative assay for infectious Rous sarcoma virus and reticuloendotheliosis virus DNAs is described. The specific infectivities of viral DNA corresponded to one infectious unit per 10(5) to 10(6) viral DNA molecules. Infection with viral DNA followed one-hit kinetics. The minimal size of infectious Rous sarcoma virus DNA was approximately 6 million daltons, whereas the minimal size of infectious reticuloendotheliosis virus DNA was larger, 10 to 20 million daltons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372391"}
{"pmid": "4372393", "title": "Reticuloendotheliosis virus nucleic acid sequences in cellular DNA.", "content": "Reticuloendotheliosis virus nucleic acid sequences in cellular DNA. Reticuloendotheliosis virus 60S RNA labeled with (125)I, or reticuloendotheliosis virus complementary DNA labeled with (3)H, were hybridized to DNAs from infected chicken and pheasant cells. Most of the sequences of the viral RNA were found in the infected cell DNAs. The reticuloendotheliosis viruses, therefore, replicate through a DNA intermediate. The same labeled nucleic acids were hybridized to DNA of uninfected chicken, pheasant, quail, turkey, and duck. About 10% of the sequences of reticuloendotheliosis virus RNA were present in the DNA of uninfected chicken, pheasant, quail, and turkey. None were detected in DNA of duck. The specificity of the hybridization was shown by competition between unlabeled and (125)I-labeled viral RNAs and by determination of melting temperatures. In contrast, (125)I-labeled RNA of Rous-associated virus-O, an avian leukosis-sarcoma virus, hybridized 55% to DNA of uninfected chicken, 20% to DNA of uninfected pheasant, 15% to DNA of uninfected quail, 10% to DNA of uninfected turkey, and less than 1% to DNA of uninfected duck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372393"}
{"pmid": "4372392", "title": "Effect of interferon upon the primary and secondary transcription of vesicular stomatitis and influenza viruses.", "content": "Effect of interferon upon the primary and secondary transcription of vesicular stomatitis and influenza viruses. The synthesis of viral complementary RNA by vesicular stomatitis virus in permissive cells can be distinguished operationally into two phases, primary transcription, which can be observed in cycloheximide treated cells, and secondary transcription, which represents the further synthesis of viral complementary RNA obtained in untreated cells. Pretreatment of mouse L cells or chicken embryo fibroblasts with the homologous interferon and, for chicken embryo fibroblast cells, poly(rI):poly(rC), inhibits the production of infectious virus and reduces the synthesis of viral complementary RNA to levels comparable to that obtained during primary transcription. Treatment of mouse L cells with interferon plus cycloheximide also gives levels of vesicular stomatitis viral complementary RNA synthesis comparable to that observed with the cycloheximide treatment alone. Similar results have been obtained for interferontreated cells subsequently infected with influenza virus (strain WSN). The results are interpreted as indicating that inhibition of virus development by interferon does not act at the level of primary transcription but rather at an intermediate step between primary and secondary transcription, such as viral protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372392"}
{"pmid": "4372394", "title": "Expression of the viral thymidine kinase gene in herpes simplex virus-transformed L cells.", "content": "Expression of the viral thymidine kinase gene in herpes simplex virus-transformed L cells. In these studies, the expression of thymidine kinase (TK) in normal and herpes simplex virus (HSV)-transformed L cells has been compared. In asynchronously dividing cultures of L cells, the TK activity rose and declined rapidly and coordinately with DNA synthesis. When net cell increase stopped, TK activity was at a minimum. In contrast, TK activity of HSV-transformed cells remained at a minimum during rapid DNA synthesis and gradually increased as the rate of DNA synthesis decreased. When net cell increase stopped, TK activity was at a maximum. In synchronous cultures of L cells, TK activity rose and fell coordinately with the rate of DNA synthesis. In synchronous cultures of HSV-transformed cells, no increase in TK activity was observed during the period of rapid DNA synthesis, i.e., the S phase. These findings indicated that the viral TK gene in HSV-transformed cells was not placed under the control of the cellular mechanisms which normally modulate the host cell TK gene. Lytic infection of HSV-transformed cells with a TK(-) mutant of HSV-1 induced a four-to fivefold increase in viral TK. The TK of HSV-1 was induced in the HSV-1-transformed cells and HSV-2 in the HSV-2-transformed cells by this TK(-) mutant. The same infection of normal L cells decreased the cellular TK activity by 80%. This stimulation, rather than inhibition, suggest that the viral gene in HSV-transformed cells retain some of its original viral characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372394"}
{"pmid": "4372395", "title": "Envelope proteins of vesicular stomatitis virus: effect of temperature-sensitive mutations in complementation groups III and V.", "content": "Envelope proteins of vesicular stomatitis virus: effect of temperature-sensitive mutations in complementation groups III and V. All five major viral proteins were synthesized in chicken embryo cells infected with vesicular stomatitis virus temperature-sensitive (ts) mutants of complementation groups III and V and maintained at the nonpermissive temperature. The distribution of these proteins among cytoplasmic cellular fractions separated on discontinuous sucrose gradients was identical for wild-type and tsIII-infected cells. Strikingly different patterns were observed for the G protein in gradients from cells infected by tsV mutants; very little, if any, G protein was found in the lightest fraction. Pulse and chase experiments with wild-type, virus-infected cells showed that protein G moves from the heaviest to the lightest fraction before being incorporated into the virion. After shift down to the permissive temperature (30 C), G protein synthesized at 39.6 C in tsV-infected cells became associated with the lightest cellular fraction and later with the released virions. In contrast, M protein, synthesized at 39.6 C in tsIII-infected cells, was not incorporated into the virions after shift down. These data strongly suggest, first, that M protein is encoded by the vesicular stomatitis gene III, and second, that incorporation of G protein in the lightest cellular fraction is a necessary step of vesicular stomatitis maturation. This step is impaired by tsV mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372395"}
{"pmid": "4372396", "title": "Effects of actinomycin D on the cytopathology induced by poliovirus in HEp-2 cells.", "content": "Effects of actinomycin D on the cytopathology induced by poliovirus in HEp-2 cells. One possible mechanism of virus-induced cell damage is that the redistributed (released) lysosomal enzymes produce the cytopathic effect during cytolytic types of infections such as poliovirus in HEp-2 cells. To determine if the lysosomal enzyme redistribution and cell damage are host-cell directed, we studied sensitivity of these events to the action of actinomycin D. By the use of actinomycin D at concentrations producing the least toxicity but maximal effectiveness in shuting down cell RNA synthesis, it was shown that the cytopathic effect and enzyme redistribution were not inhibited and, therefore, not directly controlled and induced by the cell genome in response to the virus infection. Evaluation of cytopathic effect by a phase contrast microscopy method detected changes earlier than the erythrocin B uptake method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372396"}
{"pmid": "4372397", "title": "Analysis of endonuclease R-EcoRI fragments of DNA from lambdoid bacteriophages and other viruses by agarose-gel electrophoresis.", "content": "Analysis of endonuclease R-EcoRI fragments of DNA from lambdoid bacteriophages and other viruses by agarose-gel electrophoresis. By means of agarose-gel electrophoresis, endonuclease R.EcoRI-generated fragments of DNA from various viruses were separated, their molecular weights were determined, and complete or partial fragment maps for lambda, phi80, and hybrid phages were constructed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372397"}
{"pmid": "4372398", "title": "Proteolytic cleavage of subunits of the nucleocapsid of the paramyxovirus simian virus 5.", "content": "Proteolytic cleavage of subunits of the nucleocapsid of the paramyxovirus simian virus 5. The protein subunits of the nucleocapsid of the parainfluenza virus simian virus 5 isolated from infected cells after dispersion with trypsin, chymotrypsin, or ficin are cleaved proteolytically. The molecular weights of the subunits which result from cleavage depend on the enzyme used, but are around 43,000, compared to the native subunit of 61,000. In most instances cleavage of the subunit appears to be due to the protease used to disperse the cell, and follows cell disruption. Nucleocapsids composed of native, uncleaved subunits can frequently be obtained from infected cells dispersed without a proteolytic enzyme; however, cleavage occasionally occurs even under those conditions, indicating that cellular proteases can at times cleave this protein. Nucleocapsids containing uncleaved subunits can be isolated from cells persistently infected with simian virus 5, indicating that persistent infection is not invariably associated with intracellular cleavage of this protein. Nucleocapsids composed of native subunits are hydrophobic, whereas those composed of the cleaved subunit can be dispersed in aqueous solution. It is suggested that the portion of the molecule removed by cleavage may be responsible for a specific interaction during virus assembly between the nucleocapsid and those areas of plasma membrane which contain the non-glycosylated viral membrane protein, which is also hydrophobic. An amino acid analysis of native and cleaved subunits has been done. The portion of the subunit removed by cleavage does not have a high proportion of hydrophobic residues, suggesting that those present are arranged together to form a hydrophobic domain. The N termini of both the native and cleaved subunits are blocked. This suggests that the portion of the molecule which is externally disposed and removed by cleavage contains the C terminus, and the cleaved subunit which reacts with the viral RNA contains the N terminus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372398"}
{"pmid": "4372399", "title": "Structure of the mouse mammary tumor virus: characterization of bald particles.", "content": "Structure of the mouse mammary tumor virus: characterization of bald particles. The polypeptide, antigenic, and morphological structure of the mouse mammary tumor virus was studied following protease digestion of intact virions. Intact, untreated virions (rho = 1.17 g/ml) had characteristic envelope spikes, five major polypeptides, and were precipitated by antisera against gp52. Two of the major polypeptides, with molecular weights of 52,000 (gp52) and 36,000 (gp36), had carbohydrate moieties. Protease treatment resulted in spikeless, \"bald\" particles (rho = 1.14 g/ml), which had altered surface antigenicity and which contained neither gp52 nor gp36. These data indicated that gp52 and gp36 were on the viral envelope. Bald particles retained a 28,000 dalton polypeptide (p28) which was proposed as the major internal polypeptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372399"}
{"pmid": "4372400", "title": "Hemagglutination-inhibition: rapid assay for neuraminic acid-containing viruses.", "content": "Hemagglutination-inhibition: rapid assay for neuraminic acid-containing viruses. Influenza virus particles bind rapidly to vesicular stomatitis, Sindbis, or Rauscher murine leukemia virus particles, forming mixed aggregates demonstrable by electron microscopy. The normal hemagglutinating property of influenza virus is inhibited by these viruses, providing a rapid quantitative assay. Prior treatment with neuraminidase blocks the ability of other viruses to inhibit influenza virus hemagglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372400"}
{"pmid": "4372401", "title": "Characterization of polyoma DNA-protein complexes. I. Electrophoretic identification of the proteins in a nucleoprotein complex isolated from polyoma-infected cells.", "content": "Characterization of polyoma DNA-protein complexes. I. Electrophoretic identification of the proteins in a nucleoprotein complex isolated from polyoma-infected cells. A study was undertaken to examine polyoma DNA-protein complexes. A biophysical characterization of the complexes was made, and the proteins found in such complexes were identified by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. A comparison was made between a 52S nucleoprotein complex isolated from nuclei of 26-h polyoma-infected cells and a 28S virion core complex ejected out of mature virus particles. It was found that both complexes were reduced to a 20S viral DNA component plus free protein after incubation in 1 M NaCl or Sarkosyl. Treatment of the complexes with either Pronase or 0.5 M NaCl resulted in only partial removal of proteins from the viral DNA. After fixation in formaldehyde, the 52S nucleoprotein complex had a buoyant density of 1.45 g/cm(3), and the virion core complex had a buoyant density of 1.59 g/cm(3). Sodium dodecyl sulfate-polyacrylamide gel profiles of purified polyoma virion proteins, used as a reference marker, demonstrated three capsid proteins, V1 to V3, as well as four histones, V4 to V7, which constituted about 7% of the total virion protein. Electrophoretic analysis of the proteins comprising the 52S nucleoprotein complex revealed that the same seven proteins present in the mature virion were also found in this complex. However, the ratios of the proteins in the complex were quite different from that of the mature virion, with the four histones comprising 48% of the total complex protein. A pulse-chase experiment of the nucleoprotein complex demonstrated that the 26-h complex was chased into mature virions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372401"}
{"pmid": "4372402", "title": "Molecular weight of two oncornavirus genomes: derivation from particle molecular weights and RNA content.", "content": "Molecular weight of two oncornavirus genomes: derivation from particle molecular weights and RNA content. Sedimentation analysis and intensity fluctuation spectroscopy have been used in conjunction with the Svedberg equation to determine the particle molecular weights of Rous sarcoma virus (Prague strain) and avian myeloblastosis virus (BAI strain). The molecular weights of these two viruses are (294 +/- 20) x 10(6) and (256 +/- 18) x 10(6), respectively. Values for the molecular weight of the RNA contained in each particle have been calculated as (5.58 +/- 0.5) x 10(6) and (5.88 +/- 0.5) x 10(6). Since the proportion of the viral RNA represented by 4 to 7S low-molecular-weight material is known, the molecular weight of the 60 to 70S genomes may be calculated to lie in the range (3.8 +/- 0.3 to 4.8 +/- 0.4) x 10(6) for both particles. These estimates for the molecular weight of the 60 to 70S genome are much lower than previous estimates and fall within the range of current estimates of the size of a single 35S subunit. The implications of this finding are discussed in terms of current theories for the structure of the genome of RNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372402"}
{"pmid": "4372403", "title": "Nucleic acid homology of murine type-C viral genes.", "content": "Nucleic acid homology of murine type-C viral genes. The nucleic acid sequence homology between various murine, endogenous type-C viruses (three host range classes of BALB/c virus, the AT-124 virus, and the CCL 52 virus) and two laboratory strains of murine leukemia virus (Rauscher and Kirsten) was determined by DNA:RNA hybridization. The viral sequences exhibit varying degrees of partial homology. DNA:DNA hybridizations were performed between [(3)H]DNA probes prepared from N- and X-tropic BALB/c endogenous viruses and cellular DNAs from BALB/c, NIH Swiss, and AKR inbred mouse strains as well as from California feral mice and the Asian mouse subspecies Mus musculus molossinus and M. musculus castaneus. All of these strains of mice are shown to possess multiple (six to seven per haploid genome), partially related copies of type-C virogenes in their DNAs. Thermal melting profiles of the DNA:RNA and DNA:DNA hybrids suggest that the partial homology of the viral nucleic acid sequences is the result of base alterations throughout the viral genomes, rather than the loss of discrete segments of viral sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372403"}
{"pmid": "4372405", "title": "Avian tumor virus proteins and RNA in uninfected chicken embryo cells.", "content": "Avian tumor virus proteins and RNA in uninfected chicken embryo cells. The content of proteins P19 and P15 (mol wt 19,000 and 15,000, respectively) of avian leukovirus in various types of uninfected chicken embryos has been determined by radioimmunoassay. All chicken embryos examined, including embryos which have thus far been classified as group specific (gs) antigen negative by complement fixation tests, contained these viral proteins as well as P27 as previously reported. The embryos known as \"gs antigen-positive\" type contained about five times as much of these viral proteins as did the \"gs antigen-negative\" type. The ratio of the three viral proteins was similar for all types of embryos, suggesting that the genes for these proteins are coordinately controlled. In contrast to the relatively high levels of viral internal proteins in gs antigen-negative cells, the amounts of virus-specific RNA detectable by molecular hybridization were extremely low. The levels of helper activity, which presumably reflect the level of viral envelope glycoprotein, were also generally low or undetectable in these cells. Thus, the expression of the gene for envelope glycoprotein does not appear to be controlled coordinately with the genes for viral internal proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372405"}
{"pmid": "4372404", "title": "Isolation and characterization of revertant cell lines. VI. Susceptibility of revertants to retransformation by simian virus 40 and murine sarcoma virus.", "content": "Isolation and characterization of revertant cell lines. VI. Susceptibility of revertants to retransformation by simian virus 40 and murine sarcoma virus. The susceptibility of two classes of revertants of Simian virus 40 (SV40)-transformed 3T3 cells to retransformation by SV40 or murine sarcoma virus (MSV) was studied. Both serum-sensitive and density-sensitive revertants are not retransformable by SV40. MSV can transform both types of revertants. The MSV-transformed revertants grow to high cell densities and form colonies when suspended in semi-solid methylcellulose medium, but are unable to grow in 1% calf serum. The MSV-transformed revertants produce infectious MSV and murine leukemia virus and possess the same number of chromosomes as the untransformed revertants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372404"}
{"pmid": "4372406", "title": "Levels of rat cellular RNA homologous to either Kirsten sarcoma virus or rat type-C virus in cell lines derived from Osborne-Mendel rats.", "content": "Levels of rat cellular RNA homologous to either Kirsten sarcoma virus or rat type-C virus in cell lines derived from Osborne-Mendel rats. DNA transcripts from V-NRK and RT21c rat type-C viruses were found to differ in their sequence homology to Kirsten and Harvey sarcoma viruses. V-NRK DNA transcripts consistently had homology to Kirsten and Harvey sarcoma virus, whereas RT21c DNA transcripts did not. To explain the differences, the nucleic acids and structural proteins of the two type-C viruses, released from each of two cell lines derived from Osborne-Mendel rats, were analyzed by molecular hybridization and competition radioimmunoassays. The p30 and p12 structural proteins of the two viruses were found to be highly related immunologically. In the V-NRK virus preparation, two sets of distinct RNA sequences were found in approximately equal amounts. One set is homologous to Ki-SV, and the other homologous to RT21c. In contrast, the RT21c virus preparation was found to contain a different ratio of these sequences. In this case the RT21c-like RNA sequences are present in 100-fold excess as compared to the additional Ki-SV specific sequences. Both NRK and RT21c cells contain in their DNA the full complement of Ki-SV homologous sequences, but NRK cells express much higher levels of these Ki-SV sequences in their RNA. These additional sequences, not homologous to RT21c, which are detected in uninfected NRK cellular RNA or V-NRK rat virus, could also be detected in the 60-70S RNA from a Moloney mouse type-C virus released from the NRK cells infected with the Moloney type-C virus. The results suggest that type-C viruses released from NRK cells incorporate species of RNA present in NRK cells which are homologous to Kirsten and Harvey sarcoma viruses. Either these sequences are of cellular origin, or rat cells contain two endogenous viruses with completely distinct nucleic acid sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372406"}
{"pmid": "4372407", "title": "Extent of double strandedness in avian myeloblastosis virus RNA.", "content": "Extent of double strandedness in avian myeloblastosis virus RNA. The extent of double strandedness of avian myeloblastosis virus 70S RNA has been determined from fluorescence measurements of the intercalation of ethidium bromide. We have shown that 50% of the nucleotides of 70S RNA in solution are in a stable helical configuration. This value does not include small helical regions that are too unstable to permit intercalation of the dye. The avian myeloblastosis virus RNA as it exists within the virion has the same degree of helicity as the free 70S RNA. Heating the free 70S RNA to 55 or 70 C, followed by cooling, does not measurably change the degree of helicity; the subunits therefore have as much helicity as the parent molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372407"}
{"pmid": "4372408", "title": "Mechanistic independence of avian myeloblastosis virus DNA polymerase and ribonuclease H.", "content": "Mechanistic independence of avian myeloblastosis virus DNA polymerase and ribonuclease H. Differential inhibition conditions were established for the DNA polymerase and RNase H activities of avian myeloblastosis virus (AMV) with ether-disrupted AMV and a purified enzyme preparation. The RNase H activity of ether-disrupted AMV with (rA)(n).(dT)(n) and (rA)(n).(dT)(11) as substrates was inhibited 80 to 100% by preincubation with NaF at a final reaction concentration of 27 to 30 mM. Under these conditions, the DNA polymerase activity was inhibited only 0 to 20%. Similar inhibitions were found with exogenous Rous sarcoma virus 35S and 70S RNA.DNA hybrid and phiX174 DNA.RNA hybrid as substrates. Studies were also performed with a purified enzyme preparation, in which the two activities essentially co-purified. The RNase H activity was inhibited >80% by 150 mM KCl with three different hybrid substrates, whereas the DNA polymerase activity was uninhibited. The DNA polymerase was completely inactivated by heat denaturation at 41 C or by omission of the deoxytriphosphates from the reaction mixture; the RNase H remained active. These differential inhibition conditions were used to compare the size of the DNA product synthesized with and without simultaneous RNase H action and to examine the effect of inhibition of the DNA polymerase on the size of the RNase H products. The size of the products of one activity was not affected by inhibition of the other activity. These results suggest that the AMV DNA polymerase and RNase H are not coupled mechanistically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372408"}
{"pmid": "4372410", "title": "Simian virus 40-host cell interactions. II. Cytoplasmic and nucleolar accumulation of simian virus 40 virion protein.", "content": "Simian virus 40-host cell interactions. II. Cytoplasmic and nucleolar accumulation of simian virus 40 virion protein. We have used immunofluorescence in parallel with transmission and scanning electron microscopy to characterize the unusual cytoplasmic and nucleolar accumulation of Simian virus 40 (SV40) virion protein (C antigen) at restrictive temperatures (39 to 41 C) in monkey cells infected with a temperature-sensitive mutant of SV40 defective in virion assembly, tsB11. Cytoplasmic and nucleolar accumulation of C antigen did not occur in wild-type-infected cells at any temperature. Wild-type- and tsBll-infected cells were not distinguishable at 33 C by immunofluorescence or electron microscopy. Temperature-shift experiments using metabolic inhibitors of DNA (cytosine arabinonucleoside, 20 mug/ml), RNA (actinomycin D, 5 mug/ml), and protein synthesis (cycloheximide, 2 x 10(-4) to 10 x 10(-4) M) were used to investigate the requirements for ongoing DNA, RNA, and protein synthesis in the distribution of virion protein between the nucleus, nucleolus, and cytoplasm. The transport of C antigen from the nucleolus and cytoplasm into the nucleus was complete after a temperature shift-down (41 and 39 to 33 C). Limited virus particle formation occurred after the shift-down in the presence of actinomycin D and cycloheximide, indicating some of the 39 to 41 C synthesized virion protein could be used for capsid assembly at 33 C in the absence of further virion protein synthesis. Nucleolar and cytoplasmic accumulations of C antigen occurred in the absence of drugs after a shift-up (33 to 39 C and 41 C) indicating a continuous requirement for the tsB11 mutant function. Furthermore, the virion protein synthesized at 33 C remained confined to the nucleus when the cells were shifted to 39 and 41 C in the presence of actinomycin D or cycloheximide. In the presence of cytosine arabinonucleoside, however, the virion protein accumulated in large aggregates in the nucleus and nucleolus after the shift-up, but did not migrate into the cytoplasm as it did in drug-free tsB11-infected control cells. Colchicine (10(-3) M) had no effect on the abnormal accumulation of C antigen during shift-up or shift-down experiments suggesting that microtubular transport plays little if any role in the abnormal transport of tsB11 virion protein from cytoplasm to nucleus. Although virus particles were never observed by electron microscopy and V antigen was not detected by immunofluorescence at 39 or 41 C in tsB11-infected cells, dense amorphous accumulations were formed in the nucleoli and cytoplasm. We suggest that the tsB11 function is continuously required for the normal transport of SV40 virion protein between the cytoplasm, nucleolus, and nucleus and for the assembly of capsids and virions. Several possible mechanisms for the altered tsB11 function or protein are discussed. One of the virion proteins may also be involved in some presently undetermined nucleolar function during SV40 productive infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372410"}
{"pmid": "4372409", "title": "Properties and location of poly(A) in Rous sarcoma virus RNA.", "content": "Properties and location of poly(A) in Rous sarcoma virus RNA. The poly(A) sequence of 30 to 40S Rous sarcoma virus RNA, prepared by digestion of the RNA with RNase T(1), showed a rather homogenous electrophoretic distribution in formamide-polyacrylamide gels. Its size was estimated to be about 200 AMP residues. The poly(A) appears to be located at or near the 3' end of the 30 to 40S RNA because: (i) it contained one adenosine per 180 AMP residues, and because (ii) incubation of 30 to 40S RNA with bacterial RNase H in the presence of poly(dT) removed its poly(A) without significantly affecting its hydrodynamic or electrophoretic properties in denaturing solvents. The viral 60 to 70S RNA complex was found to consist of 30 to 40S subunits both with (65%) and without (approximately 30%) poly(A). The heteropolymeric sequences of these two species of 30 to 40S subunits have the same RNase T(1)-resistant oligonucleotide composition. Some, perhaps all, RNase T(1)-resistant oligonucleotides of 30 to 40S Rous sarcoma virus RNA appear to have a unique location relative to the poly(A) sequence, because the complexity of poly(A)-tagged fragments of 30 to 40S RNA decreased with decreasing size of the fragment. Two RNase T(1)-resistant oligonucleotides which distinguish sarcoma virus Prague B RNA from that of a transformation-defective deletion mutant of the same virus appear to be associated with an 11S poly(A)-tagged fragment of Prague B RNA. Thus RNA sequences concerned with cell transformation seem to be located within 5 to 10% of the 3' terminus of Prague B RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372409"}
{"pmid": "4372413", "title": "Replication process of the parvovirus H-1. IV. H-1-specific proteins synthesized in synchronized human NB kidney cells.", "content": "Replication process of the parvovirus H-1. IV. H-1-specific proteins synthesized in synchronized human NB kidney cells. The synthesis of two virus-induced proteins, VP1 (mol wt 92,000) and VP2' (mol wt 72,000), was detected in the cell and in purified virions from H-1 parvovirus propagated in synchronous cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372413"}
{"pmid": "4372411", "title": "Murine type-C virus group-specific antigens: interstrain immunochemical, biophysical, and amino acid sequence differences.", "content": "Murine type-C virus group-specific antigens: interstrain immunochemical, biophysical, and amino acid sequence differences. The 30,000-molecular-weight internal protein, p30, was purified from seven strains of mouse type-C viruses. The individual p30's showed variation in isoelectric points and also intrastrain heterogeneity. The individual p30's could be distinguished by peptide map and quantitative complement fixation techniques with relatedness estimates of >95%. Amino terminal sequence analysis showed variability at position 4 for several p30's with complete homology otherwise through 24 residues. The intrastrain heterogeneity in p30 isoelectric points could not be explained by common contaminants, as shown by peptide mapping, and is more likely based on post-transcriptional modifications. These data provide a chemical basis for the recently described type-specific immunological properties of individual p30's.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372411"}
{"pmid": "4372414", "title": "Plaque formation with simian virus 40: enhancement by dimethyl sulfoxide.", "content": "Plaque formation with simian virus 40: enhancement by dimethyl sulfoxide. Dimethyl sulfoxide (DMSO) added to agar overlays during plaque assays of simian virus 40 (SV40) in CV1 monkey cells increases the plaque size and number and enables plaques to be read several days earlier than usual. DMSO appears to act during development of plaques, perhaps by causing cell lysis at smaller burst sizes in the presence of near-lethal DMSO concentrations. It does not act synergistically in determining virus inactivation with UV light and is equally effective on wild type and a late mutant of SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372414"}
{"pmid": "4372415", "title": "Differential effect of phenethyl alcohol on mycoplasmas and enveloped viruses.", "content": "Differential effect of phenethyl alcohol on mycoplasmas and enveloped viruses. Mycoplasmas are totally inactivated by a 20-min treatment with 1% phenethyl alcohol, whereas suspensions of enveloped viruses resist the same treatment. This treatment has proved successful in eliminating mycoplasma contamination of a virus suspension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372415"}
{"pmid": "4372412", "title": "Type-C RNA virus gene expression in human tissue.", "content": "Type-C RNA virus gene expression in human tissue. Partially purified fractions of human tissues have been analyzed by competition radioimmunoassay for the presence of two of the principle structural components of type-C RNA viruses, the major core protein (p27 to p30) and the major envelope glycopeptides (gp69/71). Screening of tissues was carried out by use of a heterologous assay system of (125)I-labeled Rauscher murine virus p30 antigen and anti-RD 114 virus serum which was found to detect a class of interspecies determinants common to murine, feline, and primate viruses. A competitor with the same apparent affinity for antibody binding as that of purified viral core proteins was found in relatively high concentration in tissues from patients with systemic lupus erythematosus, in some neoplastic tissues, and also in normal human tissues. This competitor from a lupus spleen chromatographed on phosphocellulose and showed size fractionation during gel filtration similar to known p27 to p30 viral proteins. An immunologically reactive protein was also demonstrated by immunodiffusion and by immunoprecipitation of (125)I-labeled human protein with anti-RD 114 p28 serum. Analysis of these human competitor proteins with homologous assay systems of viral core proteins and corresponding antisera showed that all, including the normal tissue extracts, appear similar to core proteins of known viruses, especially the RD 114 and woolly monkey species. A hypothesis suggested by these data is that many, if not all, humans harbor at least part of the genome of one or more type-C viruses, the properties of which are similar to those of viruses from other mammalian species, particularly primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372412"}
{"pmid": "4372416", "title": "In vitro radioisotopic labeling of proteins associated with purified polyoma virions.", "content": "In vitro radioisotopic labeling of proteins associated with purified polyoma virions. An in vitro procedure using [(14)C]formaldehyde and sodium borohydride was used to label the proteins of purified polyoma virions. This method, which labeled the three capsid proteins and the four internal histones of polyoma virus, did not alter the biological and biophysical characteristics of the virus. In addition to the seven viral proteins, five additional radioactive peaks were resolved on polyacrylamide gels. Four of these peaks could be attributed to growing the virus in the presence of serum. The fifth peak appears to be a nonhistone host-contributed protein made before infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372416"}
{"pmid": "4372417", "title": "Screening for hyperlipidemia in childhood.", "content": "Screening for hyperlipidemia in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372417"}
{"pmid": "4372418", "title": "Islet cell hyperinsulinism in adults and children.", "content": "Islet cell hyperinsulinism in adults and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372418"}
{"pmid": "4372419", "title": "Pneumocystis carinii pneumonia in an adopted Vietnamese infant. A case of diffuse, fulminant disease, with recovery.", "content": "Pneumocystis carinii pneumonia in an adopted Vietnamese infant. A case of diffuse, fulminant disease, with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372419"}
{"pmid": "4372426", "title": "Phosphoesterases of hemolytic streptococci.", "content": "Phosphoesterases of hemolytic streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372426"}
{"pmid": "4372427", "title": "Epidemiology of myxo- paramyxovirus infections among cynomolgus monkeys imported for laboratory use.", "content": "Epidemiology of myxo- paramyxovirus infections among cynomolgus monkeys imported for laboratory use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372427"}
{"pmid": "4372428", "title": "Selective adsorption of serum proteins to aerosil.", "content": "Selective adsorption of serum proteins to aerosil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372428"}
{"pmid": "4372429", "title": "The effects of amino acids and metals on the infectivity of poliovirus ribonucleic acid.", "content": "The effects of amino acids and metals on the infectivity of poliovirus ribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372429"}
{"pmid": "4372430", "title": "Growth characteristics of Bordetella pertussis in the chick tracheal organ culture.", "content": "Growth characteristics of Bordetella pertussis in the chick tracheal organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372430"}
{"pmid": "4372431", "title": "Production of mouse interferon with high titers in a large-scale suspension culture system.", "content": "Production of mouse interferon with high titers in a large-scale suspension culture system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372431"}
{"pmid": "4372432", "title": "Effect of a lactobacillus product administration on the anaerobic intestinal flora of aged adults.", "content": "Effect of a lactobacillus product administration on the anaerobic intestinal flora of aged adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372432"}
{"pmid": "4372433", "title": "Enhanced production of interferon by temperature shift-down from 37 C to 25 C in rabbit cell cultures stimulated with Newcastle disease virus.", "content": "Enhanced production of interferon by temperature shift-down from 37 C to 25 C in rabbit cell cultures stimulated with Newcastle disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372433"}
{"pmid": "4372434", "title": "Enhancing effect of interferon pretreatment on interferon production.", "content": "Enhancing effect of interferon pretreatment on interferon production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372434"}
{"pmid": "4372435", "title": "Sensitivity of various H particles of poliovirus to alkaline treatment.", "content": "Sensitivity of various H particles of poliovirus to alkaline treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372435"}
{"pmid": "4372437", "title": "A sensitive plaque assay for Sendai virus in an established line of monkey kidney cells.", "content": "A sensitive plaque assay for Sendai virus in an established line of monkey kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372437"}
{"pmid": "4372436", "title": "Typing of herpes simplex virus strains of genital and nongenital origins.", "content": "Typing of herpes simplex virus strains of genital and nongenital origins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372436"}
{"pmid": "4372438", "title": "Biochemical basis for narcotic tolerance and physical dependence.", "content": "Biochemical basis for narcotic tolerance and physical dependence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372438"}
{"pmid": "4372447", "title": "Low-renin hypertension.", "content": "Low-renin hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372447"}
{"pmid": "4372448", "title": "Tubular reabsorption of phosphate after release of complete ureteral obstruction in the rat.", "content": "Tubular reabsorption of phosphate after release of complete ureteral obstruction in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372448"}
{"pmid": "4372449", "title": "The role of angiotensin in the cardiovascular and renal response to salt restriction.", "content": "The role of angiotensin in the cardiovascular and renal response to salt restriction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372449"}
{"pmid": "4372450", "title": "Evidence for renal glomerular receptors for angiotensin II.", "content": "Evidence for renal glomerular receptors for angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372450"}
{"pmid": "4372451", "title": "Phylogeny of the renal effects of angiotensin.", "content": "Phylogeny of the renal effects of angiotensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372451"}
{"pmid": "4372452", "title": "The adrenal cortex and the kidney.", "content": "The adrenal cortex and the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372452"}
{"pmid": "4372453", "title": "A proposed cybernetic system for sodium and potassium homeostasis: coordination of aldosterone and intrarenal physical factors.", "content": "A proposed cybernetic system for sodium and potassium homeostasis: coordination of aldosterone and intrarenal physical factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372453"}
{"pmid": "4372454", "title": "Effects of adrenergic nervous system and catecholamines on systemic and renal hemodynamics, sodium and water excretion and renin secretion.", "content": "Effects of adrenergic nervous system and catecholamines on systemic and renal hemodynamics, sodium and water excretion and renin secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372454"}
{"pmid": "4372455", "title": "Vasopressin.", "content": "Vasopressin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372455"}
{"pmid": "4372456", "title": "Parathyroid hormone and calcitonin regulation of renal function.", "content": "Parathyroid hormone and calcitonin regulation of renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372456"}
{"pmid": "4372457", "title": "Estrogens and the kidney.", "content": "Estrogens and the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372457"}
{"pmid": "4372489", "title": "Estradiol receptor functions of soluble proteins from target-specific lysosomes.", "content": "Estradiol receptor functions of soluble proteins from target-specific lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372489"}
{"pmid": "4372491", "title": "The intramitochondrial distribution of the 3beta-hydroxysteroid dehydrogenase-oxosteroid isomerase. A probable redistribution artifact.", "content": "The intramitochondrial distribution of the 3beta-hydroxysteroid dehydrogenase-oxosteroid isomerase. A probable redistribution artifact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372491"}
{"pmid": "4372490", "title": "The origin of 5alpha-androstane-3alpha, 17beta-diol and its 3beta epimer in peripheral blood of immature female rats.", "content": "The origin of 5alpha-androstane-3alpha, 17beta-diol and its 3beta epimer in peripheral blood of immature female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372490"}
{"pmid": "4372492", "title": "The epidemiologic pathology of carcinomas of the large bowel.", "content": "The epidemiologic pathology of carcinomas of the large bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372492"}
{"pmid": "4372495", "title": "Intra-axonal transport and degeneration of adrenergic nerve terminals after axotomy with long and short nerve stump.", "content": "Intra-axonal transport and degeneration of adrenergic nerve terminals after axotomy with long and short nerve stump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372495"}
{"pmid": "4372496", "title": "Is adenylate cyclase the dopamine receptor?", "content": "Is adenylate cyclase the dopamine receptor?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372496"}
{"pmid": "4372497", "title": "The autonomic innervation of the exocrine pancreas.", "content": "The autonomic innervation of the exocrine pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372497"}
{"pmid": "4372498", "title": "The APUD cells of the alimentary tract in health and disease.", "content": "The APUD cells of the alimentary tract in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372498"}
{"pmid": "4372499", "title": "Normal mechanisms of fat absorption and derangements induced by various gastrointestinal diseases.", "content": "Normal mechanisms of fat absorption and derangements induced by various gastrointestinal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372499"}
{"pmid": "4372493", "title": "Gas gangrene-on the basis of 19 observations. Advantages of combining surgery with hyperbaric oxygen therapy.", "content": "Gas gangrene-on the basis of 19 observations. Advantages of combining surgery with hyperbaric oxygen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372493"}
{"pmid": "4372494", "title": "In vitro studies on the thyroid.", "content": "In vitro studies on the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372494"}
{"pmid": "4372505", "title": "Altered stearoyl-CoA desaturase activities in Morris hepatomas 5123C and 7800.", "content": "Altered stearoyl-CoA desaturase activities in Morris hepatomas 5123C and 7800.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372505"}
{"pmid": "4372506", "title": "Tumor lipids: long chain dienoic acid in sphingomyelin.", "content": "Tumor lipids: long chain dienoic acid in sphingomyelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372506"}
{"pmid": "4372507", "title": "Alleged role of boric acid in detritylation of diglyceride-alpha-trityl ethers by silicic acid.", "content": "Alleged role of boric acid in detritylation of diglyceride-alpha-trityl ethers by silicic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372507"}
{"pmid": "4372509", "title": "The intravenous L-alanine tolerance test as a means for investigating gluconeogenesis.", "content": "The intravenous L-alanine tolerance test as a means for investigating gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372509"}
{"pmid": "4372511", "title": "Preliminary study of the treatment of nephrolithiasis (calcium stones) with diphosphonate.", "content": "Preliminary study of the treatment of nephrolithiasis (calcium stones) with diphosphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372511"}
{"pmid": "4372512", "title": "Editorial: Oestrogen receptors and breast carcinoma.", "content": "Editorial: Oestrogen receptors and breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372512"}
{"pmid": "4372510", "title": "A mechanism for hyporeninemic hypoaldosteronism in chronic renal disease.", "content": "A mechanism for hyporeninemic hypoaldosteronism in chronic renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372510"}
{"pmid": "4372513", "title": "Two types of spin-labels and their interaction with phospholipid micelles and mitochondrial enzymes.", "content": "Two types of spin-labels and their interaction with phospholipid micelles and mitochondrial enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372513"}
{"pmid": "4372514", "title": "Investigation of the lysozyme macromolecule by a spin-labeling method.", "content": "Investigation of the lysozyme macromolecule by a spin-labeling method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372514"}
{"pmid": "4372515", "title": "Reaction of DNA with Girard's reagent P: kinetics of the reaction and resistance of the product to some nucleases.", "content": "Reaction of DNA with Girard's reagent P: kinetics of the reaction and resistance of the product to some nucleases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372515"}
{"pmid": "4372516", "title": "A study of nucleus-cytoplasm interrelationships in a cell-free system with isolated rat liver cell nuclei.", "content": "A study of nucleus-cytoplasm interrelationships in a cell-free system with isolated rat liver cell nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372516"}
{"pmid": "4372518", "title": "Investigation of electron transport in chloroplasts and their fragments by the ESR method. Communication I. Electron transport and kinetic characteristics of the light-induced ESR signal.", "content": "Investigation of electron transport in chloroplasts and their fragments by the ESR method. Communication I. Electron transport and kinetic characteristics of the light-induced ESR signal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372518"}
{"pmid": "4372517", "title": "An investigation of the interaction of steroids with human serum albumin by the spin-label method.", "content": "An investigation of the interaction of steroids with human serum albumin by the spin-label method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372517"}
{"pmid": "4372519", "title": "An investigation of rRNA and synthetic polyribonucleotides by the spin-label method.", "content": "An investigation of rRNA and synthetic polyribonucleotides by the spin-label method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372519"}
{"pmid": "4372521", "title": "Distribution of transcribable DNA sequences in mouse liver hepatoma chromatin.", "content": "Distribution of transcribable DNA sequences in mouse liver hepatoma chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372521"}
{"pmid": "4372520", "title": "Hemoglobin. Cooperativity and electronic properties.", "content": "Hemoglobin. Cooperativity and electronic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372520"}
{"pmid": "4372522", "title": "Covalent coupling of alkaline Bacillus subtilis protease to controlled-pore silica with a new simplified coupling technique.", "content": "Covalent coupling of alkaline Bacillus subtilis protease to controlled-pore silica with a new simplified coupling technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372522"}
{"pmid": "4372523", "title": "On the dual role of respiration.", "content": "On the dual role of respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372523"}
{"pmid": "4372525", "title": "The induction of thymidine- and IUdR-resistant variants in P388 mouse lymphoma cells by x-rays, UV and mono- and bi-functional alkylating agents.", "content": "The induction of thymidine- and IUdR-resistant variants in P388 mouse lymphoma cells by x-rays, UV and mono- and bi-functional alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372525"}
{"pmid": "4372524", "title": "Requirements for the initiation of polyphenylalanine synthesis by recombined ribosomal subunits from yeast.", "content": "Requirements for the initiation of polyphenylalanine synthesis by recombined ribosomal subunits from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372524"}
{"pmid": "4372527", "title": "The use of different test systems with yeasts for the evaluation of chemically induced gene conversions and gene mutations.", "content": "The use of different test systems with yeasts for the evaluation of chemically induced gene conversions and gene mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372527"}
{"pmid": "4372528", "title": "Comparison of the genetic activity of dimethylnitrosamine, ethyl methanesulfonate, 2-acetylaminofluorene and ICR-170 in Saccharomyces cerevisiae strains D3, D4 and D5 using in vitro assays with and without metabolic activation.", "content": "Comparison of the genetic activity of dimethylnitrosamine, ethyl methanesulfonate, 2-acetylaminofluorene and ICR-170 in Saccharomyces cerevisiae strains D3, D4 and D5 using in vitro assays with and without metabolic activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372528"}
{"pmid": "4372529", "title": "Detection of chemical mutagens using a host-mediated assay (L5178Y) mutagenesis system.", "content": "Detection of chemical mutagens using a host-mediated assay (L5178Y) mutagenesis system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372529"}
{"pmid": "4372530", "title": "The induction of micronuclei by frameshift mutagens at the time of nucleus expulsion in mouse erythroblasts.", "content": "The induction of micronuclei by frameshift mutagens at the time of nucleus expulsion in mouse erythroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372530"}
{"pmid": "4372531", "title": "The ultrastructure of the spherules of Emmonsia crescens studied by the technique of freeze-etching.", "content": "The ultrastructure of the spherules of Emmonsia crescens studied by the technique of freeze-etching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372531"}
{"pmid": "4372532", "title": "Editorial: Killer T cells.", "content": "Editorial: Killer T cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372532"}
{"pmid": "4372533", "title": "Letter: Collagenases: human and bacterial.", "content": "Letter: Collagenases: human and bacterial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372533"}
{"pmid": "4372534", "title": "Poly(C) in animal viral RNAs.", "content": "Poly(C) in animal viral RNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372534"}
{"pmid": "4372535", "title": "Detection of cell-dependent cytotoxic antibody to cells infected with herpes simplex virus.", "content": "Detection of cell-dependent cytotoxic antibody to cells infected with herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372535"}
{"pmid": "4372536", "title": "Cyclic GMP stimulates lymphocyte nucleic acid synthesis.", "content": "Cyclic GMP stimulates lymphocyte nucleic acid synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372536"}
{"pmid": "4372537", "title": "Membrane antigens of murine leukaemia cells.", "content": "Membrane antigens of murine leukaemia cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372537"}
{"pmid": "4372539", "title": "Collagenase activity in experimental hepatic fibrosis.", "content": "Collagenase activity in experimental hepatic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372539"}
{"pmid": "4372538", "title": "Autologous human B and T lymphoblastoid cell lines.", "content": "Autologous human B and T lymphoblastoid cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372538"}
{"pmid": "4372540", "title": "Activity of CNS depressants related to hydrophobicity.", "content": "Activity of CNS depressants related to hydrophobicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372540"}
{"pmid": "4372541", "title": "Caffeine inhibits induction of endogenous C-type virus.", "content": "Caffeine inhibits induction of endogenous C-type virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372541"}
{"pmid": "4372542", "title": "Rapid in vivo assay for murine lymphatic leukaemia viruses.", "content": "Rapid in vivo assay for murine lymphatic leukaemia viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372542"}
{"pmid": "4372543", "title": "Antigenic inhibition of cell-mediated cytotoxicity against tumour cells.", "content": "Antigenic inhibition of cell-mediated cytotoxicity against tumour cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372543"}
{"pmid": "4372544", "title": "Human times mouse hybrid cells segregating mouse chromosomes and isozymes.", "content": "Human times mouse hybrid cells segregating mouse chromosomes and isozymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372544"}
{"pmid": "4372546", "title": "Evolution of C-type viral genes: inheritance of exogenously acquired viral genes.", "content": "Evolution of C-type viral genes: inheritance of exogenously acquired viral genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372546"}
{"pmid": "4372545", "title": "Transcription, translation and maturation of succinate dehydrogenase during cell cycle.", "content": "Transcription, translation and maturation of succinate dehydrogenase during cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372545"}
{"pmid": "4372548", "title": "Octopamine receptors on Aplysia neurones mediate hyperpolarisation by increasing membrane conductance.", "content": "Octopamine receptors on Aplysia neurones mediate hyperpolarisation by increasing membrane conductance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372548"}
{"pmid": "4372547", "title": "Binding of interferon to gangliosides.", "content": "Binding of interferon to gangliosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372547"}
{"pmid": "4372549", "title": "Association of polyanion resistance with tumorigenicity and other properties in BHK-21 cells.", "content": "Association of polyanion resistance with tumorigenicity and other properties in BHK-21 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372549"}
{"pmid": "4372550", "title": "Ultrastructural localization of herpes simplex virus antigens on rabbit corneal cells using sheep antihuman IgG antihorse ferritin hybrid antibodies.", "content": "Ultrastructural localization of herpes simplex virus antigens on rabbit corneal cells using sheep antihuman IgG antihorse ferritin hybrid antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372550"}
{"pmid": "4372551", "title": "Effects on the neonate of prednisone and azathioprine administered to the mother during pregnancy.", "content": "Effects on the neonate of prednisone and azathioprine administered to the mother during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372551"}
{"pmid": "4372552", "title": "Serum concentrations of parathyroid hormone in infants, children, and adolescents.", "content": "Serum concentrations of parathyroid hormone in infants, children, and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372552"}
{"pmid": "4372553", "title": "Peripheral neuropathy and lead poisoning in a child with sickle-cell anemia. Case report and review of the literature.", "content": "Peripheral neuropathy and lead poisoning in a child with sickle-cell anemia. Case report and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372553"}
{"pmid": "4372554", "title": "Extending the scope of the VATER association: definition of the VATER syndrome.", "content": "Extending the scope of the VATER association: definition of the VATER syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372554"}
{"pmid": "4372555", "title": "Occipito-facial-cervico-thoracic-abdomino-digital dysplasia; Jarcho-Levin syndrome of vertebral anomalies. Report of six cases and review of the literature.", "content": "Occipito-facial-cervico-thoracic-abdomino-digital dysplasia; Jarcho-Levin syndrome of vertebral anomalies. Report of six cases and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372555"}
{"pmid": "4372556", "title": "Possible model reactions for the nitrate reductases.", "content": "Possible model reactions for the nitrate reductases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372556"}
{"pmid": "4372557", "title": "Oral contraceptive for men.", "content": "Oral contraceptive for men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372557"}
{"pmid": "4372558", "title": "Voltage clamp studies of glutamate synapse.", "content": "Voltage clamp studies of glutamate synapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372558"}
{"pmid": "4372559", "title": "Cell-mediated immunity to Epstein-Barr virus and a blocking factor in patients with infectious mononucleosis.", "content": "Cell-mediated immunity to Epstein-Barr virus and a blocking factor in patients with infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372559"}
{"pmid": "4372560", "title": "A rapid and simple procedure for the determination of guanosine 3',5'-monophosphate by use of the protein-binding method.", "content": "A rapid and simple procedure for the determination of guanosine 3',5'-monophosphate by use of the protein-binding method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372560"}
{"pmid": "4372563", "title": "Cancer genetics: urological system. II.", "content": "Cancer genetics: urological system. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372563"}
{"pmid": "4372572", "title": "Appearance of alpha-fetoprotein in rat serum during induction of primary hepatoma with regard to development of histological changes in liver tissue.", "content": "Appearance of alpha-fetoprotein in rat serum during induction of primary hepatoma with regard to development of histological changes in liver tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372572"}
{"pmid": "4372571", "title": "Dynamics of alpha-fetoprotein production compared to alpha 2-macroglobulin during induction of primary hepatoma with 4-dimethylaminoazobenzene in rats.", "content": "Dynamics of alpha-fetoprotein production compared to alpha 2-macroglobulin during induction of primary hepatoma with 4-dimethylaminoazobenzene in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372571"}
{"pmid": "4372573", "title": "Protein synthesizing activities of ribosome-like structure isolated from avian myeloblastosis virus in chicken cell-free protein synthesis.", "content": "Protein synthesizing activities of ribosome-like structure isolated from avian myeloblastosis virus in chicken cell-free protein synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372573"}
{"pmid": "4372574", "title": "Difference in density of nuclear pores in normal and malignant fibroblasts of Syrian hamster.", "content": "Difference in density of nuclear pores in normal and malignant fibroblasts of Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372574"}
{"pmid": "4372578", "title": "For goodness sake - let your patients sleep.", "content": "For goodness sake - let your patients sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372578"}
{"pmid": "4372581", "title": "Chronic respiratory problems in neuromyopathic disorders: their nature and management.", "content": "Chronic respiratory problems in neuromyopathic disorders: their nature and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372581"}
{"pmid": "4372583", "title": "I-cell disease (mucolipidosis II): a lysosomopathy.", "content": "I-cell disease (mucolipidosis II): a lysosomopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372583"}
{"pmid": "4372582", "title": "Asthma: current concepts.", "content": "Asthma: current concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372582"}
{"pmid": "4372587", "title": "Roadside resuscitation.", "content": "Roadside resuscitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372587"}
{"pmid": "4372590", "title": "Familial and acquired hyperlipoproteinemias in children and adolescents.", "content": "Familial and acquired hyperlipoproteinemias in children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372590"}
{"pmid": "4372591", "title": "Soft-tissue swellings.", "content": "Soft-tissue swellings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372591"}
{"pmid": "4372592", "title": "Relipidation of phospholipid-depleted microsomal particles with high glucose 6-phosphatase activity.", "content": "Relipidation of phospholipid-depleted microsomal particles with high glucose 6-phosphatase activity. Microsomal particles enriched up to 20-fold in glucose 6-phosphatase activity (as compared to crude microsomal fractions) were prepared from livers of phenobarbital-treated, normal, and diabetic rats by a method involving sucrose-density gradient centrifugation through a layer containing deoxycholate, followed by flotation of the delipidated particles in a phospholipid-detergent mixture. The flotation with phospholipid resulted in the extraction of additional protein, in a corresponding increase in specific activity, and in relipidation of the particles to their original phospholipid content. Detergents alone did not extract any additional protein. Relipidation caused a change in the properties of the microsomal membrane, as indicated by a 4-fold decrease in the K(m) for glucose 6-phosphate and mannose 6-phosphate. The maximal rate was not affected. The crude homogenate of diabetic rat liver contained more latent enzyme than that of normal rats. The diabetic rats also yielded purified microsomal particles of specific glucose 6-phosphatase activity twice that of normal and five times that of phenobarbital-treated rats, indicating that some regulatory mechanism exists for the incorporation of different amounts of the enzyme into the endoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372592"}
{"pmid": "4372593", "title": "Degradation of pseudoviral DNA after infection of mouse cells with polyoma pseudovirions.", "content": "Degradation of pseudoviral DNA after infection of mouse cells with polyoma pseudovirions. When mouse cells are infected with [(3)H]-thymidine-labeled polyoma pseudovirions, as much as 11% of the input pseudoviral radioactivity is found in the recipient cell DNA. However, the radioactivity found in the recipient cell DNA virtually disappears when nonradioactive thymidine and deoxycytidine, or D-arabinosyl cytosine, are added to the medium. The radioactivity found in the recipient cell DNA appears to be the result of the breakdown of pseudoviral DNA to precursors of DNA and the utilization of these precursors for the synthesis of cell DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372593"}
{"pmid": "4372594", "title": "Aldosterone-induced increase in protein phosphatase activity of toad bladder.", "content": "Aldosterone-induced increase in protein phosphatase activity of toad bladder. A study has been carried out of the effect of aldosterone on the endogenous phosphorylation and dephosphorylation of membrane-bound and of soluble proteins from toad bladder. Membrane-bound protein D (apparent molecular weight, 49,000), a protein which may possibly be involved in the regulation of sodium transport across the mucosal epithelium of toad bladder, contained a substantial fraction of the radioactive phosphate incorporated into membrane proteins; moreover, it was the only protein to appear consistently in autoradiographs of polyacrylamide gels of phosphorylated membrane proteins. Pretreatment of toad bladder slices with aldosterone caused an increase in the endogenous dephosphorylation of membrane-bound protein D. A half-maximal increase in this dephosphorylation occurred at an aldosterone concentration of 20-40 nM. The increase in protein D phosphatase activity induced by aldosterone was prevented by inhibitors of RNA and protein synthesis as well as by spironolactone, a specific antagonist of aldosterone. The mineralocorticoid, 9alpha-fluorohydrocortisone, also increased protein D phosphatase activity, but testosterone did not. Aldosterone also increased the removal of [(32)P]phosphate from protein D in the cell sap. In contrast to the increase in protein D phosphatase activity, aldosterone had little effect on the phosphorylation of protein D by endogenous protein D kinase. In some experiments, effects of aldosterone and of cAMP, qualitatively similar to those found with protein D, were also observed on the phosphorylation and dephosphorylation of a protein with an apparent molecular weight of 37,000, in both the microsomal and cell sap fractions. No consistent effect of preincubation with aldosterone or of cAMP was observed on any membrane-bound or cell sap protein other than protein D and the 37,000 dalton protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372594"}
{"pmid": "4372595", "title": "Synthesis of viral DNA in the cytoplasm of duck embryo fibroblasts and in enucleated cells after infection by avian sarcoma virus.", "content": "Synthesis of viral DNA in the cytoplasm of duck embryo fibroblasts and in enucleated cells after infection by avian sarcoma virus. TWO LINES OF EVIDENCE INDICATE THAT SYNTHESIS OF VIRAL DNA OCCURS IN THE CYTOPLASM OF DUCK EMBRYO FIBROBLASTS INFECTED WITH AVIAN SARCOMA VIRUS: (i) viral DNA is detected first in the cytoplasmic fraction of infected cells and subsequently in the nuclear fraction; and (ii) viral DNA is synthesized at a normal rate in cells infected after enucleation with cytochalasin B. The presence of viral DNA in the cytoplasmic fraction is not a consequence of leakage of newly synthesized viral DNA from the nucleus, since it remains in nuclear fractions late after infection when integration of viral DNA into the host genome is inhibited by ethidium bromide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372595"}
{"pmid": "4372596", "title": "Enhancement of dopamine-stimulated adenylate cyclase activity in rat caudate after lesions in substantia nigra: evidence for denervation supersensitivity.", "content": "Enhancement of dopamine-stimulated adenylate cyclase activity in rat caudate after lesions in substantia nigra: evidence for denervation supersensitivity. Unilateral radiofrequency lesions or chemical lesions with 6-hydroxydopamine were produced in the substantia nigra of rat brain in order to destroy dopaminergic innervations to caudate nucleus and thereby to produce functional denervation supersensitivity. Both types of lesions resulted in enhanced stimulation of caudate adenylate cyclase (EC 4.6.1.1) activity by dopamine at all dopamine concentrations tested, with more marked enhancement at the lower concentrations. Response to another dopamine agonist, 1-(3,4-dihydroxybenzyl)-4-(20pyrimidinyl) piperazine (S584) was also enhanced. 6-Hydroxydopamine lesions resulted in selective enhancement of the dopamine-stimulated component of adenylate cyclase, whereas radiofrequency lesions resulted also in a marked decrease in basal activity. It is postulated that the basal activity of caudate represents primarily an adenylate cyclase distinct from that stimulated by dopamine and destroyed only by the less selective radiofrequency lesion. The enhancement of dopamine-sensitive adenylate cyclase after lesions serves as indirect evidence for a significant role of this system in the transmitter function of dopamine and indicates, furthermore, that it is directly involved in dopamine receptor supersensitivity in vivo produced by denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372596"}
{"pmid": "4372597", "title": "Receptors from glucocorticoid-sensitive lymphoma cells and two clases of insensitive clones: physical and DNA-binding properties.", "content": "Receptors from glucocorticoid-sensitive lymphoma cells and two clases of insensitive clones: physical and DNA-binding properties. Mouse lymphoma tissue culture cells (S49.1A) are normally killed by dexamethasone, a synthetic glucocorticoid hormone. Dexamethasone-resistant clones have been selected from this line, some of which retain the ability to specifically bind dexamethasone. Addition of [(3)H]dexamethasone to cultures, followed by cell fractionation, reveals that the nuclear transfer of hormone-receptor complexes in some of these variant clones is deficient (nt(-)), while others show increased nuclear transfer (nt(i)) relative to the parental line. Two independently selected members of each class have been studied here, in an effort to elucidate the molecular determinants involved in the receptor-nucleus interaction in vivo. The labeled receptors in cell-free extracts bind to DNA-cellulose, but only after previous incubation of the extract at 20 degrees , similar to the treatment required for cell-free interaction of receptors with nuclei. More importantly, the apparent DNA-binding affinity of the nt(-) receptors is lower than the wild type, whereas the nt(i) receptors bind DNA with an affinity higher than the parental molecules. The parallelism of nuclear and DNA binding, together with the observations that the receptors from the variants have sedimentation properties different from the wild-type cells, lead us to conclude that (i) these variants may contain altered receptor molecules and (ii) DNA is probably the primary nuclear binding site for steroid receptors in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372597"}
{"pmid": "4372599", "title": "Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells.", "content": "Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells. The poly(A) tract found in eukaryotic mRNA was used to study methylation in mRNA obtained from Novikoff hepatoma cells. Methyl labeling of RNA was achieved with L-[methyl-(3)H]methionine under conditions that suppress radioactive incorporation into the purine ring. RNA that contains a poly(A) segment was obtained from polysomal RNA by chromatography on oligo(dT)-cellulose. Sucrose density gradient centrifugation of this RNA revealed a pattern expected for mRNA. The composition of the methyl-labeled nucleosides in the RNA was analyzed after complete enzymatic degradation to nucleosides. By use of DEAE-cellulose (borate) chromatography, which separates 2'-O-methylnucleosides from normal and base-methylated nucleosides, about 50% of the radioactivity was recovered in the 2'-O-methylnucleoside fraction and 50% in the base-methylnucleoside fraction. High-speed liquid chromatography (Aminex A-5) of the 2'-O-methylnucleoside fraction produced four peaks coincident with the four 2'-O-methylnucleoside standards. Analysis of the base-methylnucleoside fraction revealed a unique pattern. While ribosomal RNA and tRNA possessed complex base-methylnucleoside patterns, the distribution in mRNA was quite simple, consisting predominantly of N(6)-methyladenosine. These results demonstrate a unique distribution of methylated nucleosides in mRNA. By analogy to ribosomal RNA synthesis, the presence of methylnucleosides in mRNA may reflect a cellular mechanism for the selective processing of certain mRNA sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372599"}
{"pmid": "4372598", "title": "Induction of type-C RNA virus by cycloheximide: increased expression of virus-specific RNA.", "content": "Induction of type-C RNA virus by cycloheximide: increased expression of virus-specific RNA. Mouse cells contain the genetic information for multiple endogenous type-C RNA viruses. The mechanisms by which the cell controls expression of these naturally integrated viruses are not yet known. Recently, chemicals that inhibit protein synthesis have been shown to induce a specific type-C virus at high frequency from BALB/c mouse embryo cells. In the present studies, virus activation in response to a representative translational inhibitor, cycloheximide, is demonstrated to be transient, with virus release primarily occurring within the first 12-24 hr following drug exposure. Analysis of virus-specific RNA in cells by molecular hybridization revealed an absolute increase in viral RNA concentration in cycloheximide-treated cells. This was blocked by simultaneous exposure of the cells to actinomycin D. Further, inhibition of RNA synthesis during but not subsequent to cycloheximide exposure prevented virus activation. These findings show that virus induction by cycloheximide requires de novo RNA synthesis during but not after drug exposure and suggest that the required RNA species may be that of the virus itself. The present results are consistent with the hypothesis that translational inhibitors prevent synthesis of a labile protein whose normal action is to inhibit viral RNA transcription or to cause degradation of viral RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372598"}
{"pmid": "4372600", "title": "The glycine synaptic receptor: evidence that strychnine binding is associated with the ionic conductance mechanism.", "content": "The glycine synaptic receptor: evidence that strychnine binding is associated with the ionic conductance mechanism. The ability of a series of anions to inhibit [(3)H]strychnine binding to spinal cord synaptic membranes correlates closely with their neurophysiologic capacity to reverse inhibitory postsynaptic potentials in the mammalian spinal cord. Seven neurophysiologically active anions are also effective inhibitors of [(3)H]strychnine binding with mean effective doses ranging from 160 to 620 mM. Seven other anions that are ineffective neurophysiologically also fail to alter strychnine binding. Chloride inhibits strychnine binding in a noncompetitive fashion. Hill plots of the displacement of [(3)H]strychnine by chloride give coefficients of 2.3-2.7. The inhibition of strychnine binding by these anions suggests that strychnine binding is closely associated with the ionic conductance mechanism for chloride in the glycine receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372600"}
{"pmid": "4372601", "title": "Differences between laboratory strains of Epstein-Barr virus based on immortalization, abortive infection, and interference.", "content": "Differences between laboratory strains of Epstein-Barr virus based on immortalization, abortive infection, and interference. Biologic activities of extracellular Epstein-Barr virus (EB virus) from two laboratory strains, namely, P(3)J-HR-1 (P-H) from Burkitt lymphoma and B95-8 (B95) from infectious mononucleosis, were compared. Virus stocks from both sources contained approximately the same number of virions. Virus from the P-H line induced \"early antigen\" in six nonproducer EB virus genome carrier cell lines; virus from B95 did not induce \"early antigen.\" Extracellular virus from B95 regularly caused lymphocytes from human umbilical cords to form continuous lines (immortalization); P-H virus did not cause primary cultures of human lymphocytes to grow continuously. B95 virus stimulated DNA synthesis as determined by rate of incorporation of [(3)H]thymidine into acid-insoluble material; P-H virus did not stimulate DNA synthesis. Pretreatment of lymphocytes with undiluted P-H virus inhibited immortalization and stimulation of DNA synthesis by B95 virus. The inhibitory properties of the P-H virus were sedimented at 100,000 x g and inactivated by heat and UV irradiation; interference by the P-H virus was neutralized by human serum with antibody to EB virus and not by antibody-negative human serum. The hypothesis most consistent with these results is that the P-H virus is defective in gene(s) needed for initiation of immortalization. We speculate that the absence of this gene allows early antigen to be expressed upon super-infection of nonproducer cell lines. The availability of two laboratory strains of EB virus which differ in biologic behavior provides starting material for analysis of the mechanism of lymphocyte immortalization by EB virus and of virus structural differences which affect immortalization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372601"}
{"pmid": "4372602", "title": "Carbohydrate composition of the membrane glycoprotein of vesicular stomatitis virus grown in four mammalian cell lines.", "content": "Carbohydrate composition of the membrane glycoprotein of vesicular stomatitis virus grown in four mammalian cell lines. The carbohydrate composition of the membrane glycoprotein of vesicular stomatitis virus has been determined for virus grown in four different mammalian cell lines. The glycoprotein contains mannose, galactose, N-acetylglucosamine, and neuraminic acid as the major carbohydrate components, whereas N-acetyl-galactosamine and fucose are present in lesser amounts. The glycoprotein contains approximately 9-10% carbohydrate regardless of the host cell in which it is synthesized. Small quantitative differences are evident in the composition of the component sugars of the glycoprotein when the virus is grown in different host cells, and the glycoprotein of virus grown in a mouse fibroblast line (L cells) lacks fucose. The major oligosaccharide moieties of the virus glycoprotein from all cells are approximately the same size (3000-3400 daltons). The data presented here, in conjunction with previous data, indicate that the viral glycoprotein contains two major oligosaccharide constituents regardless of the host cell in which it is synthesized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372602"}
{"pmid": "4372603", "title": "Guanosine 3':5'-monophosphate-dependent protein kinases in mammalian tissues.", "content": "Guanosine 3':5'-monophosphate-dependent protein kinases in mammalian tissues. The mammalian protein kinase activity stimulated preferentially by low concentrations of guanosine 3':5'-monophosphate (cyclic GMP), but not by adenosine 3':5'-monophosphate (cyclic AMP), was readily assayed in a modified incubation system that contained a neutral phosphate buffer, protein kinase modulator, and arginine-rich histone. Cyclic GMP-dependent protein kinase activity assayed under these conditions was about two to three orders of magnitude higher than that previously detected. The enzyme activity occurred in all guinea pig and rat tissues (lung, heart, aorta, brain, liver, ileum, adipose, and pancreatic islets) examined. The activity can be separated from the cyclic AMP-dependent protein kinase activity, also present in the same tissues, by means of either Sephadex G-200 gel filtration or ammonium sulfate fractionation. The cyclic GMP-dependent enzyme preparations had K(a) values for cyclic GMP ranging from 0.03 to 0.12 muM, compared to the K(a) values for cyclic AMP ranging from 0.6 to 3.8 muM. The presence of phosphate and protein kinase modulator was essential for maximal cyclic GMP-dependent enzyme activity. The occurrence of high levels of cyclic GMP-dependent protein kinase activity in mammalian tissues clearly suggests that it may serve as a \"target\" enzyme for cyclic GMP, mediating many biological effects of this cyclic nucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372603"}
{"pmid": "4372605", "title": "Initiation of oncogenic transformation of mouse lymphocytes in vitro by Abelson leukemia virus.", "content": "Initiation of oncogenic transformation of mouse lymphocytes in vitro by Abelson leukemia virus. While C-type RNA viruses are known to induce leukemias and lymphomas, oncogenic transformation of lymphoid cells by them in vitro has not been reported. In this study, splenocytes from female BALB/c mice were infected in vitro with Abelson virus, a C-type RNA virus that induces nonthymic lymphomas and plasmacytomas in mice. The cells were transplanted into recipients of different karyotype, either male BALB/c mice or hybrid BALB/c x AL/N (CALF1) mice, which bear the Rb(5.19)1Wh translocation. Transplants of eight of the resulting tumors (one plasmacytoma and seven lymphomas) contained cells of donor BALB/c karyotype, indicating that transformation of splenocytes occurred in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372605"}
{"pmid": "4372604", "title": "Stimulation of synthesis of free chondroitin sulfate chains by beta-D-xylosides in cultured cells.", "content": "Stimulation of synthesis of free chondroitin sulfate chains by beta-D-xylosides in cultured cells. Previous studies have shown that D-xylose partially overcomes the puromycin inhibition of chondroitin sulfate synthesis in cultured chick embryo chondrocytes. Likewise, D-xylose stimulates chondroitin sulfate synthesis by limb bud mesenchyme cells previously treated with BrdU or limb bud cartilage cells treated with puromycin. The studies reported here show that p-nitrophenyl-beta-D-xylopyranoside and 4-methyl-umbelliferyl-beta-D-xylopyranoside cause a much greater stimulation than does D-xylose and are active at much lower concentrations. In contrast to D-xylose, the xylosides strikingly stimulate chondroitin sulfate synthesis in predifferentiated mesenchyme cells. The xylosides stimulate synthesis of chondroitin sulfate by rat glial cell tumor cells (RC-6), a mouse neuroblastoma (C1300, NB41A), and two strains of cultured rat hepatoma cells (HTC, H(4)). These results indicate that certain types of nonconnective tissue cells contain the enzymic machinery for synthesis of chondroitin sulfate which is normally not utilized because of limited synthesis of core protein and/or xylosyltransferase. The beta-xylosides may be used as a probe of the capacity of various cell types to synthesize sulfated glycosaminoglycans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372604"}
{"pmid": "4372606", "title": "Correlation between thermal death and membrane fluidity in Bacillus stearothermophilus.", "content": "Correlation between thermal death and membrane fluidity in Bacillus stearothermophilus. Paramagnetic resonance spectra of spin labels partitioned into spheroplast membranes of Bacillus stearothermophilus indicate lateral lipid phase separations. Cells adjust their lipid composition in response to temperature changes so that the same change of state in membrane phospholipids is achieved at the respective growth temperature. A temperature-sensitive mutant that fails to change its lipid composition above a certain temperature can survive only up to the higher temperature boundary for lateral phase separation. These data are interpreted to indicate that the maximal and minimal growth temperatures of thermophiles are regulated by the onset and conclusion of phase separations of the particular lipid composition they synthesize. It is suggested that isolated lipid domains are required for functional membrane assembly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372606"}
{"pmid": "4372607", "title": "Chromosome assignment of the T-antigen gene of simian virus 40 in African green monkey cells transformed by adeno 7-SV40 hybrid.", "content": "Chromosome assignment of the T-antigen gene of simian virus 40 in African green monkey cells transformed by adeno 7-SV40 hybrid. Somatic cell hybrids between mouse cells deficient in thymidine kinase [ATP:thymidine 5'-phosphotransferase (EC 2.7.1.75)] and two different monkey cell lines transformed by an adeno 7-SV40 hybrid have been produced using both a semiselective and a double selective procedure. Concordant segregation of the expression of SV40 T antigen with a specific monkey chromosome has been observed in all the mouse-monkey hybrid clones examined. Subcloning of three SV40 T antigen positive hybrid clones resulted in their segregation into SV40 T antigen-positive and negative subclones. Positive correlation between the SV40 T antigen and the same monkey chromosome has been observed in all the subclones examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372607"}
{"pmid": "4372608", "title": "Alterations in glucose metabolism in chick-embryo cells transformed by Rous sarcoma virus: intracellular levels of glycolytic intermediates.", "content": "Alterations in glucose metabolism in chick-embryo cells transformed by Rous sarcoma virus: intracellular levels of glycolytic intermediates. Chick-embryo cells, transformed with Rous sarcoma virus, show enhanced rates of sugar transport and glycolysis. Determination of intracellular concentrations of glycolytic intermediates suggests that the enhanced glycolytic flux is due to increased activities of hexokinase (ATP:D-hexose 6-phosphotransferase, EC 2.7.1.1), phosphofructokinase, (ATP:D-fructose-1-phosphate 6-phosphotransferase, EC 2.7.1.56), and pyruvate kinase (ATP:pyruvate 2-O-phosphotransferase, EC 2.7.1.40), and not directly to the increased glucose transport. This conclusion is supported by the finding that the intracellular concentration of free glucose is decreased, rather than increased, in the transformed cells. The present observations suggest that the increased glycolytic flux is related to an increased rate of phosphorylation of glucose, and that hexokinase in the transformed cells is at least partly released from its normal control mechanism involving feedback inhibition by glucose-6-P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372608"}
{"pmid": "4372609", "title": "Myosin is a component of the cell surface of cultured cells.", "content": "Myosin is a component of the cell surface of cultured cells. Antisera to myosin from mouse L929 cells, mouse uterus, and rabbit skeletal muscle have been prepared in goats. Each antiserum shows specific reaction by immunodiffusion only to the myosin against which it was prepared. Antiserum against L cell myosin agglutinates L929 cells and shows surface localization in unfixed cells by indirect immunofluorescence. This reaction is prevented by immunoabsorption with L cell myosin, but not by absorption with mouse uterine or rabbit skeletal muscle myosins. Elution of the antibody from L cell myosin antiserum that absorbs to fixed L cells yields antibody reactive to L cell myosin in immunodiffusion. At the ultrastructural level, surface localization is also evident with a peroxidase bridge immunocytologic method as a uniform distribution of surface label. Antiserum against L cell myosin also shows localization on the surface of other cells of rodent origin (3T3-4, NRK, MNRK, KNRK, and MEF) and HeLa cells, but not with some other cells of human origin (ALL and WI-38). The reactivity with antibody of the plasma membrane myosin is unaffected by trypsin treatment or fixation with 0.5-2.0% formalin. These results strongly suggest that myosin in cultured nonmuscle cells is a component of the plasma membrane, a finding of possible significance in studying the mechanisms regulating the motility, morphology, and growth of these cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372609"}
{"pmid": "4372610", "title": "Evidence for the involvement of sulfhydryl oxidation in the regulation of fat cell hexose transport by insulin.", "content": "Evidence for the involvement of sulfhydryl oxidation in the regulation of fat cell hexose transport by insulin. Previous studies have shown that the oxidants Cu(++), H(2)O(2), and diamide mimic the stimulatory effect of insulin on 3-O-methylglucose transport in isolated fat cells. The present experiments were designed to determine whether sulfhydryl oxidation plays a key role in the activation of the glucose transport system. It was found that reductants such as dithiothreitol inhibited 3-O-methylglucose transport rates and that this effect was reversible when cells were washed free of reducing agent. Treatment of cells with 1 mM N-ethylmalcimide for 5 min completely blocked the actions of insulin and oxidants on hexose transport without affecting control transport system activity. Under these conditions, binding of (125)I-labeled insulin to fat cell surface receptors was inhibited by only about 50%. Addition of insulin or oxidants to fat cells for 10 min before addition of N-ethylmaleimide completely prevented the inhibitory effect of N-ethylmaleimide on the activated transport system. This protective effect on transport rates appears to reside at a site that is altered by insulin subsequent to hormone-receptor interaction, since prior treatment of fat cells with insulin did not prevent the partial inhibitory effect of N-ethylmaleimide on insulin receptors. Furthermore, treatment of cells with N-ethylmaleimide after incubation with insulin prevented the elevated transport rates from returning to control levels when either the cells were washed free of hormone or insulin binding to its receptors was disrupted by trypsin digestion. However, transport rates in these cells treated with N-ethylmaleimide remained sensitive to cytochalasin B, phlorizin, and reductants. These data suggest that a component of the glucose transport system in isolated fat cells must be maintained in its disulfide state for expression of transport activity. Further, the results are consistent with the concept that the binding of insulin to cell surface receptors triggers sulfhydryl oxidation in this component, which prevents its reaction with N-ethylmaleimide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372610"}
{"pmid": "4372611", "title": "Viral DNA in transformed cells. III. The amounts of different regions of the SV40 genome present in a line of transformed mouse cells.", "content": "Viral DNA in transformed cells. III. The amounts of different regions of the SV40 genome present in a line of transformed mouse cells. (32)P-Labeled SV40 DNA was treated sequentially with restricting endonucleases EcoRI and Hpa I, and the resulting four fragments of DNA were separated by gel electrophoresis. The kinetics of renaturation of each of the fragments and of complete SV40 DNA were measured in the presence of DNA extracted from the SVT2 line of SV40-transformed mouse cells. It was found that these cells contain about six copies of a segment of DNA which includes the early region of the SV40 genome, and about one copy of the late viral sequences. To map the region of the viral genome which is transcribed in SVT2 cells, separated strands of each of the four fragments were prepared and hybridized to total transformed cell RNA. Part of the E strands of the two DNA fragments (A and C) which span the early region of the SV40 genome were found to enter the hybrid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372611"}
{"pmid": "4372613", "title": "Further comparison of predicted and experimentally determined structure of adenylate kinase.", "content": "Further comparison of predicted and experimentally determined structure of adenylate kinase. An analysis is made of various predictive methods used to locate alpha-helices and beta-sheets in proteins. The analysis is based on attempts to locate the alpha-helices and beta-sheets in adenylate kinase (ATP:AMP phosphotransferase EC 2.7.4.3) from the sequence without prior knowledge of the x-ray findings. Specification of the beta-sheet breaking and alpha-helix breaking tripeptides, a method independent of the others combined with the best of the other methods would substantially reduce the prediction of nonexistent beta-sheets and to a lesser extent would aid in locating alpha-helices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372613"}
{"pmid": "4372612", "title": "Vitamin D: concerning the relationship between molecular topology and biological function.", "content": "Vitamin D: concerning the relationship between molecular topology and biological function. Structure-function relationships for vitamin D, its metabolites, and analogs are discussed with particular emphasis on the A-ring conformation. It is emphasized that the A-ring of these seco-steroids consists of a pair of rapidly equilibrating chair conformers. As a consequence, different chair conformations produce different orientations of substituent groups in the A-ring. It is proposed that the 1alpha-hydroxyl of 1alpha,25-dihydroxyvitamin D(3) or its geometric equivalent in analogs must occupy the equatorial, as opposed to the axial, orientation for optimization of biological activity. This proposal is discussed in relation to existing published data on structure-function relationships and the steroid hormone model of action for the biologically active form of vitamin D. This three-dimensional topological model suggests the synthesis of other vitamin D analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372612"}
{"pmid": "4372614", "title": "Reciprocal inhibition of mouse leukemia virus infection by Fv-1 allele cell extracts.", "content": "Reciprocal inhibition of mouse leukemia virus infection by Fv-1 allele cell extracts. Soluble extracts of mouse cells with Fv-1(n) or Fv-1(b) gene alleles specifically and reciprocally inhibit infection of B- or N-tropic mouse leukemia viruses in permissive cell cultures. NB-tropic virus infection was not inhibited by either cell extract. Extracts from Fv-1(-) cells did not inhibit infection by the three virus host-range types, but N- or B-tropic virus infection of Fv-1(-) cells was inhibited by extracts of the nonpermissive cells, and Fv-1(nb) cell extracts inhibited both viruses. The maximum degree of inhibition was 50-80% as determined by immunofluorescent or plaque assays, with extracts containing up to 500 mug/ml of nonpermissive cell protein. The inhibitor(s) is relatively unstable since activity is lost after 2 hr at 37 degrees or 30 min at 56 degrees . The inhibitor(s) was most effective if added 2 hr before or within 2 hr after infection, did not react with the virus directly, inhibit virus attachment, or inhibit the normal cell functions tested. These results indicate that nonpermissive mouse cells contain a product, possibly determined by the Fv-1 gene, which inhibits some early postpenetration event(s) in leukemia virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372614"}
{"pmid": "4372615", "title": "Evidence for crossing-over between avian tumor viruses based on analysis of viral RNAs.", "content": "Evidence for crossing-over between avian tumor viruses based on analysis of viral RNAs. The RNAs of several avian tumor virus recombinants that had inherited their focus-forming ability from a sarcoma virus and their host range marker from a leukosis virus were investigated. Electrophoretic analyses showed that the cloned sarcoma virus recombinants contained only size class a RNA, although they had acquired a marker that resided on class b RNA in the leukosis virus parent. Class a RNA of different recombinant clones, derived from the same pair of parental viruses and selected for the same biological markers, differed slightly in electrophoretic mobility from each other and from the parental sarcoma virus. They were also found to have different fingerprints of RNase T1-resistant oligonucleotides. The average complexity of the 60-70S RNA prepared from Prague Rous sarcoma virus of subgroup B was estimated to be 3.5 x 10(6) daltons from the size of 20 RNase T1-resistant oligonucleotides, which represented 3.9% of the RNA and that of a recombinant to be 3.3 x 10(6) daltons from 23 oligonucleotides, which represented 4.7% of the RNA. This result suggests that the genome of wild-type and of recombinant RNA tumor viruses is polyploid. The sum of these observations led us to propose that recombination among avian tumor viruses occurred by crossing-over between homologous pieces of nucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372615"}
{"pmid": "4372617", "title": "Biological activity of a growth factor for ovarian cells.", "content": "Biological activity of a growth factor for ovarian cells. The biological activity of a protein growth factor is described. This factor was isolated from bovine pituitary tissue, and its activity was tested on cells of rat ovarian origin. Activity was assayed as growth-promoting potential measured by cell counts and is concentrationdependent. Similar growth stimulation was not produced by several cyclic nucleotides tested, neither was there crossreactivity between this growth factor and a chemically similar one produced by rat liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372617"}
{"pmid": "4372616", "title": "Changing the actions of neuroactive drugs by changing brain protein synthesis.", "content": "Changing the actions of neuroactive drugs by changing brain protein synthesis. Diminution of cerebral protein synthesis diminished the cerebral responses of mice to some neuroactive drugs, while an increase in synthesis increased the responses. Protein synthesis in whole brains (tested in vitro) was diminished by giving living mice different inhibitors by different routes. The inhibitors tested (chloramphenicol, cycloheximide, and puromycin) diminished the behavioral responses of the mice to levodopa without affecting either its cerebral uptake or its conversion to dopamine. A diminution of the reactions of dopaminergic receptors was suggested by the diminished responses to the dopaminergic drug, apomorphine, while participation of cholinergic ones was suggested by experiments with oxotremorine. Proof that receptors had been specifically involved was secured on homogenized caudate nuclei from chloramphenicol-treated mice, in which the dopamine-activated production of cyclic AMP was markedly diminished. A stimulator of cerebral protein synthesis, the artificial double-stranded RNA, poly(I).poly(C), increased the behavioral responses to these three drugs while it increased the dopamine-activated production of cyclic AMP. Since all these experimental increases or decreases in the responses to drugs required the lapse of only a few hours, proteins with rapid turnover rates must be critical in the activation of several kinds of cerebral receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372616"}
{"pmid": "4372618", "title": "The pancreatic beta-cell recognition of insulin secretagogues: does cyclic AMP mediate the effect of glucose?", "content": "The pancreatic beta-cell recognition of insulin secretagogues: does cyclic AMP mediate the effect of glucose? Insulin release and the content of cAMP were studied in microdissected pancreatic islets of noninbred ob/ob (obese) mice. In the absence of 3-isobutyl-1-methylxanthine, a phosphodiesterase inhibitor, 20 mM glucose had no effect on cAMP save a very small initial rise detectable by a freeze-stop perifusion technique only. However, combined with this methylxanthine, 20 mM glucose produced significant increases of cAMP both in perifused islets and in islets conventionally incubated in closed vials. Glucose shared this capacity to raise the cAMP level with D-glyceraldehyde and 1,3-dihydroxyacetone. Isobutylmethylxanthine (0.05-1.0 mM) or 5 mug/ml of cholera toxin, an activator of adenylate cyclase, also increased the islet cAMP level; the effects of the methylxanthine, whether or not combined with cholera toxin, were potentiated by glucose. Isobutylmethylxanthine (0.05-1.0 mM) or 5 mug/ml of cholera toxin potentiated insulin release in response to 20 mM glucose. However, only 0.5-1.0 mM isobutylmethylxanthine stimulated insulin release in the presence of 3 mM glucose, whereas 0.05-0.1 mM isobutylmethylxanthine or 5 mug/ml of cholera toxin had no effect on secretion at the low glucose concentration. These discrepancies between cAMP-promoting and insulin-releasing activities suggest that glucose does not initiate insulin release by activating the beta-cell adenylate cyclase. By being metabolized in the beta-cells, glucose may both create a release-initiating signal not identical with cAMP and enhance cAMP formation, leading to potentiation of the effect of the initiator signal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372618"}
{"pmid": "4372619", "title": "Purification and separation of pyridine nucleotide-linked dehydrogenases by affinity chromatography techniques.", "content": "Purification and separation of pyridine nucleotide-linked dehydrogenases by affinity chromatography techniques. A number of different dehydrogenases have been shown to bind to Sepharose-bound N(6)-(6-aminohexyl)-AMP. These dehydrogenases can be specifically eluted by binary adducts of NAD(+) or with cofactor gradients. In such manner pure enzymes can be obtained from crude extracts, as demonstrated in the purification on a preparative scale of lactate dehydrogenase from dogfish muscle. The data presented indicate the usefulness of general ligands as affinity agents. The techniques are particularly adaptable for the isolation of human mutant enzymes in blood or in the purification and concentration of enzymes present at low levels in fluids or tissues, as shown in the extensive purification of serum lactate dehydrogenase and glucose 6-phosphate dehydrogenase from hemolysate. lsoenzymes with different affinities for co-enzymes can be separated by affinity techniques. Application of affinity techniques may lead to the separation of isoenzymes or mutant enzymes that are not separable by electrophoretic methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372619"}
{"pmid": "4372620", "title": "The contribution of subunits of thyroid stimulating hormone to the binding and biological activity of thyrotropin.", "content": "The contribution of subunits of thyroid stimulating hormone to the binding and biological activity of thyrotropin. The binding of bovine TSH (thyroid stimulating hormone), LH (luteinizing hormone), and their subunits to the TSH receptor of beef thyroid membranes was compared to stimulation by these agents of adenylate cyclase [ATP pyrophosphate-lyase(cyelizing), EC 4.6.1.1] in the same membranes, glucose oxidation in dog thyroid slices, and the secretory process in mouse thyroids in vitro (colloid droplet formation) and in vivo (hormone release). The beta-subunits of TSH and LH can bind to the TSH receptor and can activate thyroid function in vitro. In contrast, the alpha-subunit of TSH binds negligibly to the TSH receptor and has very low potency for stimulation of thyroid function (except for colloid droplet formation). Neither binding nor the biological activity of the beta-subunits can be accounted for by TSH contamination, whereas this cannot be ruled out for alpha-TSH. LH binds to the TSH receptor even better than the beta-subunit of TSH but the increased binding does not result in a corresponding activation of thyroid function. Neither alpha- nor beta-TSH alone can induce more than 4-8% of the response to intact TSH in any of the investigated parameters. It is proposed that the beta-subunit has within its structure the primary determinants which are necessary to stimulate biological activity, whereas the alpha-subunit imposes conformational changes on the beta-subunit which in intact TSH promote binding and biological activity commensurately but in LH promote only binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372620"}
{"pmid": "4372621", "title": "Reversibility of the pyrophosphoryl transfer from ATP to GTP by Escherichia coli stringent factor.", "content": "Reversibility of the pyrophosphoryl transfer from ATP to GTP by Escherichia coli stringent factor. The stringent factor-catalyzed, ribosome-dependent synthesis of guanosine polyphosphates is found to be reversible. The reverse reaction specifically requires 5'-AMP as the pyrophosphoryl acceptor, and guanosine 5'-triphosphate-3'-diphosphate is preferentially utilized as the pyrophosphoryl donor. The primary products of the reaction are GTP and ATP. The reverse reaction is strongly inhibited by the antibiotics thiostrepton and tetracycline, and by ATP and beta-gamma-methylene-adenosine-triphosphate, but not by ADP, GTP, and GDP. The reverse reaction occurs under conditions for nonribosomal synthesis. The overall reaction for stringent factor-catalyzed guanosine polyphosphate formation may thus be formulated: (p)pp5'G + ppp5'A right harpoon over left harpoon (p)pp5'G3'pp + p5'A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372621"}
{"pmid": "4372622", "title": "Distribution and fate of synthetic lipid vesicles in the mouse: a combined radionuclide and spin label study.", "content": "Distribution and fate of synthetic lipid vesicles in the mouse: a combined radionuclide and spin label study. Single compartmental spherules of various lipid constituents (vesicles), enclosing (99m)TcO(4) (-) as a radioactive marker, were injected intravenously into C(3)H mice, and the distribution of radioactivity was studied. About 25% of the administered radioactivity was present in the liver 5 min and 30 min after the injection of vesicles composed of phosphatidylcholine and gangliosides, which were sonicated for 5 min (standard preparation). About 10-20% of the radioactivity remained in the circulation. By use of a nonradioactive spin label (tempocholine) enclosed within vesicles, intact vesicles were demonstrated in the circulation for 46 min after intravenous injection. The distribution of radioactivity from (99m)TcO(4) (-) inside vesicles is very different from that of free (99m)TcO(4) (-) or of (99m)Tc sulfur colloid. Increase in the length of sonication or incorporation of cholesterol into the wall of the vesicles enhanced hepatic levels and reduced blood levels of radioactivity. These same manipulations also slowed the rate of transfer of (99m)TcO(4) (-) out of vesicles in dialysis experiments in vitro. Addition of phosphatidic acid, phosphatidylethanolamine, or phosphatidylserine to the standard constituents did not greatly alter the distribution of radioactivity in vivo but did increase the number and type of active coupling sites on the outside of the vesicle. The results indicate that vesicles might be valuable as carriers of diagnostic or therapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372622"}
{"pmid": "4372623", "title": "Sequence arrangements in clonal isolates of polyoma defective DNA.", "content": "Sequence arrangements in clonal isolates of polyoma defective DNA. Five clonal isolates of purified polyoma defective DNA [Fried, M. (1974) J. Virol. 13, 939-946] have been examined by electron microscopy. Four isolates (D-92, D-74, D-50, and D-47) are largely homogeneous in sequence, whereas, the fifth isolate (D-80) is somewhat heterogeneous.Polyoma nondefective DNA is cleaved in a unique region of the genome by the EcoR(I) endonuclease. Hybridization of the resulting linear molecules with randomly nicked defective DNA reveals distinguishable types of heteroduplex structures for each of the different defective DNAs. Although the defective DNAs are shorter than polyoma nondefective DNA, the heteroduplex experiments demonstrate that they are not simply deletion mutants containing only a portion of the viral genome. Three isolates (D-92, D-50, and D-47) contain regions of homology to polyoma DNA covalently linked to non-homologous regions. One isolate (D-74) contained no regions of detectable homology to polyoma DNA. Another isolate (D-80) contained a large proportion of molecules with duplicated-inverted regions. Some of these isolates of defective DNA may contain specific host sequences at the site(s) of integration of the polyoma genome during the lytic cycle in mouse cells. A process we term \"abortive replication\" may explain the formation of different types of defective DNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372623"}
{"pmid": "4372624", "title": "AKR murine leukemia virus genome: frequency of sequences in DNA of high-, low-, and non-virus-yielding mouse strains.", "content": "AKR murine leukemia virus genome: frequency of sequences in DNA of high-, low-, and non-virus-yielding mouse strains. Studies with a single-stranded DNA probe complementary to the RNA of mouse-tropic AKR murine leukemia virus indicate that the complete genome of the AKR-type murine leukemia virus is present in the DNA of high- and low-virus-yielding mouse strains, while DNA of non-virus-yielding strains contains only a part of the genome. Furthermore, in those strains where the genome is complete, two populations of virus-specific DNA sequences can be identified (more abundant and less abundant species) according to their rate of association with the probe. Low-virus-yielding mouse strains contain fewer copies of the less abundant species and, consequently, fewer complete viral genomes than do high-virus-yielding strains. Thus, in the ten strains tested, there is a good correlation between completeness of the genome of AKR-type murine leukemia virus in cellular DNA and the capacity of the cells to release infectious AKR-type murine leukemia virus. Moreover, the number of complete viral genomes correlates with the frequency of infectious virus production by virus-positive strains. DNA from wild Mus musculus also contained viral sequences, the sample tested showing reassociation kinetics identical to the non-virus-producing strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372624"}
{"pmid": "4372625", "title": "The nucleotide sequence complexity of avian tumor virus RNA.", "content": "The nucleotide sequence complexity of avian tumor virus RNA. The nucleotide sequence complexity of 60-70S RNA of Rous sarcoma virus was determined from the molar yields of 11 pure oligonucleotides of known chain length, obtained from [(32)P]RNA of Rous sarcoma virus by T1 RNase digestion and two-dimensional polyacrylamide gel electrophoresis. We calculate an apparent chain length of about 9800 nucleotides, corresponding to a molecular weight of 3.4 x 10(6). Assuming the molecular weight of 60-70S RNA of Rous sarcoma virus to be about 10(7), our data suggest that the virus genome consists of identical, or very similar, nucleotide sequences repeated three to four times.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372625"}
{"pmid": "4372627", "title": "Activation of protein kinase by physiological concentrations of cyclic AMP.", "content": "Activation of protein kinase by physiological concentrations of cyclic AMP. When determined under the usual conditions of an excess of ligand over protein, the concentration of cyclic AMP necessary to activate pure preparations of cyclic AMP-dependent protein kinase (EC 2.7.1.37; ATP:-protein protein phosphotransferase) half-maximally is in the range of 0.2-0.3 muM when casein or glycogen synthetase is used as the substrate, i.e., essentially the same as the concentration of the nucleotide that is found in resting skeletal muscle. The apparent dissociation constant for cyclic AMP bound to the protein kinase is also about 0.2-0.3 muM when measured under similar conditions. The concentration of the protein kinase in muscle is relatively high (0.23 muM), however, and under these conditions the apparent activation constant of the enzyme for cyclic AMP is raised so that an increase in cyclic AMP levels in the tissue would cause a concomitant increase in protein kinase activity over a wide range of nucleotide concentration. As a result, it is unnecessary to invoke compartmentalization of cyclic AMP to explain how it can control protein kinase activity in vivo. Another factor that may increase the effectiveness of changes in cyclic AMP concentration is the heat-stable protein inhibitor of protein kinase that may function to inhibit the activity of nearly all the protein kinase catalytic subunit dissociated by basal concentrations of cyclic AMP. Finally, the near equity between the concentration of cyclic AMP binding sites and the ligand itself provides a potential mechanism whereby agents can affect the total cyclic AMP content without directly affecting adenylate cyclase, cyclic AMP phosphodiesterase, or cyclic AMP transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372627"}
{"pmid": "4372626", "title": "Establishment of a clone of mouse hypothalamic neurosecretory cells synthesizing neurophysin and vasopressin.", "content": "Establishment of a clone of mouse hypothalamic neurosecretory cells synthesizing neurophysin and vasopressin. Hypothalamic cells taken from 14-day-old mouse embryos were cultured for 6 days and transformed with simian virus 40. After cloning, a homogeneous cell population was obtained. Its morphological, Ultrastructural, biochemical, and immunochemical properties were studied. These cells possess ultrastructural features of primitive neurosecretory cells. They synthesize (35)S-labeled protein components that have the molecular weight and isoelectric focusing behavior of, and display the same immunoreactivity as, neurophysin. In addition, a (35)S-labeled peptidic fraction with a molecular weight close to 1000 is synthesized and is radioimmunologically indistinguishable from vasopressin. Immunochemical staining shows that both neurophysin and vasopressin are localized in the cytoplasm. These observations strongly suggest that a clone of mouse hypothalamic neurosecretory cells has been obtained with the synthesizing capacities of secretory neurons of the magnocellular hypothalamic nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372626"}
{"pmid": "4372628", "title": "Collagenase production by endotoxin-activated macrophages.", "content": "Collagenase production by endotoxin-activated macrophages. Peritoneal exudate macrophages, when exposed to bacterial lipopolysaccharide in culture, were found to produce collagenase (EC 3.4.24.3). This enzyme was not detected in extracts of the macrophages or in media from nonstimulated macrophage cultures. Lipidcontaining fractions of the lipopolysaccharide, including a glycolipid from the rough mutant of Salmonella minnesota (R595) and lipid A, were potent stimulators of collagenase production. The lipid-free polysaccharide fraction had no effect. Cycloheximide prevented the production of collagenase by endotoxin-treated macrophages, suggesting that it was newly synthesized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372628"}
{"pmid": "4372630", "title": "The primary structure of high density apolipoprotein-glutamine-I.", "content": "The primary structure of high density apolipoprotein-glutamine-I. The major protein constituent of human plasma high density lipoproteins has been isolated and its complete amino-acid sequence determined. The protein, designated apolipoprotein-glutamine-I by the presence of carboxyl-terminal glutamine, is a single polypeptide chain of 245 amino-acid residues, including three residues of methionine. The protein is devoid of cysteine, cystine, and isoleucine. Cleavage of apolipoprotein-glutamine-I with cyanogen bromide yields four fragments with 94, 90, 36, and 25 amino acids. The amino-acid sequence of each fragment was determined by conventional methods, with proteolytic digestion with trypsin, chymotrypsin, and thermolysin. The alignment of the cyanogen bromide fragments was determined by the isolation of the methionine-containing tryptic peptides from apolipoprotein-glutamine-I. Inspection of the sequence of apolipoprotein-glutamine-I suggests an interesting distribution of amino acids that may account for its helical structure and its ability to bind and transport lipid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372630"}
{"pmid": "4372629", "title": "Evidence for cholinergic synapses between dissociated rat sympathetic neurons in cell culture.", "content": "Evidence for cholinergic synapses between dissociated rat sympathetic neurons in cell culture. Sympathetic principal neurons were dissociated from superior cervical ganglia of new-born rats, and grown in cell culture. In electrophysiological experiments two types of excitatory synapses were found. One, which was relatively rare, was shown to operate by electrical transmission. The other, the predominant type, had several characteristics of chemical transmission, and pharmacological evidence indicated it was cholinergic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372629"}
{"pmid": "4372632", "title": "Change in state of spin labels bound to sarcoplasmic reticulum with change in enzymic state, as deduced from ascorbate-quenching studies.", "content": "Change in state of spin labels bound to sarcoplasmic reticulum with change in enzymic state, as deduced from ascorbate-quenching studies. The ATPase (EC 3.6.1.3) of sarcoplasmic reticulum vesicles was reacted to various extents with thiol-directed spin labels. By suspension of the preparation in appropriate solutions, the enzyme could be placed and held in certain intermediate states of the ATPase cycle, or it could be set into steady-state catalysis. Ascorbate added to the system destroyed the spin-label signals with undetectable distortion of the electron paramagnetic resonance spectrum. In general, in the presence of ascorbate, undestroyed signal as a function of time could be described as the sum of two first-order reductions going on in separate compartments with different ascorbate concentrations. In different enzymatic states the proportion of total signal in the two compartments was different, but the first-order velocity constants remained the same. If the labeled membrane was first attacked with Triton, then exposed to ascorbate, signal was destroyed according to a single first-order constant, equal to the faster of the two constants observed with intact membrane, and equal to the constant whereby ascorbate attacks free label in solution. The data were reconciled by a simple rotary model, envisioning that an enzymatic state corresponds to an average angular position of the ATPase and thereby determines the proportion of labeled thiols exposed to external and internal ascorbate concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372632"}
{"pmid": "4372631", "title": "Host control of endogenous murine leukemia virus gene expression: concentrations of viral proteins in high and low leukemia mouse strains.", "content": "Host control of endogenous murine leukemia virus gene expression: concentrations of viral proteins in high and low leukemia mouse strains. Two of the major molecular components of murine leukemia virus particles, the internal protein (p30) and the envelope glycoprotein (gp69/71) have been measured in the spleens of normal, 6- to 10-week-old mice of various inbred strains and crosses. Both proteins were detected in virtually all mice. Extracts of high leukemia, high murine leukemia virus strains (AKR, C58, PL) showed high levels of both proteins; extracts of other strains usually showed lower levels. Of particular interest, however, were the exceptions to these general observations: (1) Very little gp69/71 could be detected in spleens of BALB mice, and this trait was dominant in crosses with AKR and DBA/2, both of which express a high level of gp69/71. Thymus-deficient BALB/c-nu/nu (nude) mice, in contrast, showed a higher concentration of gp69/71 typical of other low leukemia strains, suggesting that the virtual absence of the protein in normal BALB/c mice may result from immunologic suppression. (2) With C57L, C57BL/10Sn, and C57BL/6 strains the concentration of p30 was lower, in some cases much lower, than would be expected from the concentration of gp69/71. (3) DBA/2 mice showed high levels of gp69/71, 10-fold greater than that of p30, whereas congenic DBA/2-Fv-1(b) mice showed the opposite pattern. (4) Mice of 129-G(IX) (-) strain showed no detectable levels of either p30 or gp69/71 proteins, although the congenic 129 (G(IX) (+)) showed appreciable levels of both. The absence of these proteins in 129-G(IX) (-) mice is a recessive trait, as F(1) hybrids with AKR and DBA/2 showed appropriate levels of both proteins. It is concluded that expression of viral p30 and gp69/71 proteins in mice is not coordinately linked and that expression is complex, being influenced by several genes, including Gv-1, H-2, Fv-1, and probably still others.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372631"}
{"pmid": "4372633", "title": "13C nuclear magnetic resonance spectroscopic evidence for hydrophobic lipid-protein interactions in human high density lipoproteins.", "content": "13C nuclear magnetic resonance spectroscopic evidence for hydrophobic lipid-protein interactions in human high density lipoproteins. Phosphatidylcholines, sphingomyelins, cholesterol, and cholesterol esters were enriched with (13)C by chemical synthesis in specific positions of their hydrophilic groups and aliphatic chains. Their spin-lattice relaxation times were determined in organic solvents. The substances were organized as liposomes and recombined with total human high density apolipoproteins and the two separated main components, apolipoprotein A-I (apoLp-Gln-I) and apolipoprotein A-II (apoLp-Gln-II). These (13)C nuclear magnetic resonance data established that in reassembled high density lipoproteins the phospholipid molecules bind to the apoprotein moieties with their hydrophobic fatty acid chains and not with their hydrophilic zwitterionic groups. Apolipoprotein A-I preferentially binds phosphatidylcholine, although its lipid-binding capacity is smaller than that of apolipoprotein A-II. Apolipoprotein A-II avidly reassembles with sphingomyelin by hydrophobic interactions. A model of the molecular organization of the high density lipoportein particle has been derived.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372633"}
{"pmid": "4372634", "title": "13C nuclear magnetic resonance spectroscopy of native and recombined lipoproteins.", "content": "13C nuclear magnetic resonance spectroscopy of native and recombined lipoproteins. (13)C nuclear magnetic resonance data on native and recombined lipoproteins are reported. [Methyl-(13)C]phosphatidylcholine, [methyl-(13)C]sphingomyelin, 1,2-[dioleoyl-1-(13)C]-sn-phosphatidylcholine and cholesteryl-[1-(13)C]oleate were enriched with 90% carbon-13 in respective molecules by chemical synthesis and used for recombination experiments with high density lipoprotein apoproteins. Relaxation times for these specifically enriched lipids in organic solvents, (2)H(2)O, and lipid-protein complexes isolated by ultracentrifugal flotation, were measured. The results show that both the phosphatidylcholine and sphingomyelin polar headgroups have the same hydrophilic environment in either sonicated lipid particles or reassembled lipoproteins, and suggest that ionic interaction of lipid and apolipoproteins is of minor importance in the formation of plasma lipoprotein complexes. Our experiments indicate that (13)C nuclear magnetic resonance spectroscopy will contribute to the understanding of lipidprotein interaction in lipoproteins and membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372634"}
{"pmid": "4372636", "title": "Simian virus 40 T antigen binds to DNA.", "content": "Simian virus 40 T antigen binds to DNA. The T antigen of simian virus 40, which may play a role in the control of viral DNA replication, is recovered from nuclei of cells transformed by simian virus 40 in several forms sedimenting at different rates. The large molecular weight forms are converted to the smallest (5 S) form by high salt, suggesting that they differ in the degree of aggregation. All the forms of the antigen bind efficiently to double-stranded DNA-cellulose columns at pH 6.2 and low salt, and elute in two fractions: one at pH 8.0 and low salt, the other at pH 8.0 and high salt. The antigen has little affinity for single-stranded DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372636"}
{"pmid": "4372637", "title": "Necrolytic migratory erythema with glucagon-secreting tumour of the pancreas.", "content": "Necrolytic migratory erythema with glucagon-secreting tumour of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372637"}
{"pmid": "4372635", "title": "Type C viral expression in primate tissues.", "content": "Type C viral expression in primate tissues. Nucleic acid sequences homologous to a [(3)H]DNA transcript prepared from an endogenous baboon type C virus are readily detected in both the cellular DNA and RNA of several different Old World monkeys. Competitive radioimmunoassays for the major viral protein (p30) of baboon type C viruses detect viral antigen in a normal stumptail spleen and a rhesus ovarian carcinoma. The p30 antigen from these tissues is closely related by several immunologic criteria to the p30 protein of baboon type C viruses. The results indicate that normal primate tissues transcribe endogenous viral-specific RNA and translate at least one viral structural protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372635"}
{"pmid": "4372638", "title": "Diagnosis and management of insulinoma.", "content": "Diagnosis and management of insulinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372638"}
{"pmid": "4372639", "title": "Emiocytosis: a possible molecular mechanism.", "content": "Emiocytosis: a possible molecular mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372639"}
{"pmid": "4372642", "title": "Equilibrium between metabolic pathways producing energy: a key factor in regulating lipolysis.", "content": "Equilibrium between metabolic pathways producing energy: a key factor in regulating lipolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372642"}
{"pmid": "4372643", "title": "Cyclophosphates VI. Cyclophosphates as substrates and effectors of phosphodiesterase.", "content": "Cyclophosphates VI. Cyclophosphates as substrates and effectors of phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372643"}
{"pmid": "4372644", "title": "Sodium preference induced by angiotensin in the rat.", "content": "Sodium preference induced by angiotensin in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372644"}
{"pmid": "4372645", "title": "The concept of the quasi-abstinence effect and its use in the investigation of dependence mechanisms.", "content": "The concept of the quasi-abstinence effect and its use in the investigation of dependence mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372645"}
{"pmid": "4372646", "title": "Effects of ACTH on conditioned suppression: a time and strength of conditioning analysis.", "content": "Effects of ACTH on conditioned suppression: a time and strength of conditioning analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372646"}
{"pmid": "4372647", "title": "Duration of paradoxical sleep necessary for the acquisition of conditioned avoidance in the rat.", "content": "Duration of paradoxical sleep necessary for the acquisition of conditioned avoidance in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372647"}
{"pmid": "4372641", "title": "Polypeptide influences on attention, memory and anxiety in man.", "content": "Polypeptide influences on attention, memory and anxiety in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372641"}
{"pmid": "4372650", "title": "Proceedings: Evolutionary role of neuromelanin.", "content": "Proceedings: Evolutionary role of neuromelanin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372650"}
{"pmid": "4372651", "title": "Proceedings: Drug and sociotherapy in the aftercare of schizophrenic patients.", "content": "Proceedings: Drug and sociotherapy in the aftercare of schizophrenic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372651"}
{"pmid": "4372652", "title": "The effect of internally deposited plutonium-239 on the lysosomes of rat liver.", "content": "The effect of internally deposited plutonium-239 on the lysosomes of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372652"}
{"pmid": "4372653", "title": "The extraction of the yet unused wealth of information in diagnostic radiology.", "content": "The extraction of the yet unused wealth of information in diagnostic radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372653"}
{"pmid": "4372654", "title": "Adenohypophyseal function during cerebral angiography.", "content": "Adenohypophyseal function during cerebral angiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372654"}
{"pmid": "4372648", "title": "Effect of daytime alpha rhythm maintenance on subsequent sleep.", "content": "Effect of daytime alpha rhythm maintenance on subsequent sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372648"}
{"pmid": "4372649", "title": "Heart rate levels of black and white newborns.", "content": "Heart rate levels of black and white newborns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372649"}
{"pmid": "4372657", "title": "Prostaglandin-sepharose: application to the purification of bovine lung 15 (S) -hydroxyprostaglandin dehydrogenase.", "content": "Prostaglandin-sepharose: application to the purification of bovine lung 15 (S) -hydroxyprostaglandin dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372657"}
{"pmid": "4372658", "title": "The hypothalamic \"savage\" syndrome.", "content": "The hypothalamic \"savage\" syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372658"}
{"pmid": "4372660", "title": "Experimental sheep pox. A histological and ultrastructural study.", "content": "Experimental sheep pox. A histological and ultrastructural study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372660"}
{"pmid": "4372661", "title": "Oestrogen excretion by sows with induced cystic ovarian follicles.", "content": "Oestrogen excretion by sows with induced cystic ovarian follicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372661"}
{"pmid": "4372659", "title": "Inhibition of hepatic drug metabolism by cyclic 3',5'-adenosine monophosphate.", "content": "Inhibition of hepatic drug metabolism by cyclic 3',5'-adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372659"}
{"pmid": "4372640", "title": "Antagonism of the dipsogenic action of intraseptal angiotensin II in the rat.", "content": "Antagonism of the dipsogenic action of intraseptal angiotensin II in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372640"}
{"pmid": "4372664", "title": "Acute lymphoblastic leukemia of childhood: results of combination therapy.", "content": "Acute lymphoblastic leukemia of childhood: results of combination therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372664"}
{"pmid": "4372662", "title": "Fluorescent antibody inhibition for determination of serum antibodies against the enterotoxin of Clostridium perfringens type A.", "content": "Fluorescent antibody inhibition for determination of serum antibodies against the enterotoxin of Clostridium perfringens type A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372662"}
{"pmid": "4372675", "title": "Studies on human serum high-density lipoproteins. II. Isolation of subfractions in the cold.", "content": "Studies on human serum high-density lipoproteins. II. Isolation of subfractions in the cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372675"}
{"pmid": "4372676", "title": "Megaduodenum. A case with bacterial overgrowth, deconjugation of bile salts, malabsorption, and polyneuropathy.", "content": "Megaduodenum. A case with bacterial overgrowth, deconjugation of bile salts, malabsorption, and polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372676"}
{"pmid": "4372677", "title": "Ultrastructural changes in jejunal epithelial cells in liver cirrhosis.", "content": "Ultrastructural changes in jejunal epithelial cells in liver cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372677"}
{"pmid": "4372679", "title": "Adrenocortical function in children with juvenile rheumatoid arthritis and other connective tissue disorders.", "content": "Adrenocortical function in children with juvenile rheumatoid arthritis and other connective tissue disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372679"}
{"pmid": "4372678", "title": "FL 1039 in bacteriuria following prostatectomy. A double-blind comparison with pivampicillin and placebo.", "content": "FL 1039 in bacteriuria following prostatectomy. A double-blind comparison with pivampicillin and placebo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372678"}
{"pmid": "4372674", "title": "Emphysematous cholecystitis--an important clinical variant of acute cholecystitis.", "content": "Emphysematous cholecystitis--an important clinical variant of acute cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372674"}
{"pmid": "4372682", "title": "Reversal of catecholamine refractoriness by inhibitors of RNA and protein synthesis.", "content": "Reversal of catecholamine refractoriness by inhibitors of RNA and protein synthesis. The generation of adenosine 3',5'-monophosphate (cyclic AMP) in response to catecholamines in the 2B subclone of RGC6 rat glioma cells previously exposed to norepinephrine and refractory to further norepinephrine addition is substantially increased by addition of inhibitors of RNA and protein synthesis. The time course of the effect of these inhibitors on cyclic AMP concentration suggests that rapid protein synthesis and turnover are involved in catecholamine refractoriness. Norepinephrine induction of cyclic nucleotide phosphodiesterase is demonstrable in RGC6 cells but not in the 2B subclone. Thus, catecholamine refractoriness cannot be attributed to induction of phosphodiesterase. This implies that induction of a protein or proteins, important in catecholamine refractoriness, affects the synthesis rather than the degradation of cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372682"}
{"pmid": "4372715", "title": "Leukemia and lymphoma in experimental and domestic animals.", "content": "Leukemia and lymphoma in experimental and domestic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372715"}
{"pmid": "4372716", "title": "Etiologic factors in autoimmune hemolytic anemia.", "content": "Etiologic factors in autoimmune hemolytic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372716"}
{"pmid": "4372717", "title": "Psychotherapy with donors and recipients of kidney transplants.", "content": "Psychotherapy with donors and recipients of kidney transplants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372717"}
{"pmid": "4372718", "title": "The West Philadelphia Community Mental Health Consortium in retrospect: supraprocess and infraprocess.", "content": "The West Philadelphia Community Mental Health Consortium in retrospect: supraprocess and infraprocess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372718"}
{"pmid": "4372719", "title": "Mental health counselors--new professionals? The NIMH pilot group ten years later.", "content": "Mental health counselors--new professionals? The NIMH pilot group ten years later.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372719"}
{"pmid": "4372720", "title": "Behavioral effects of cortisol in man.", "content": "Behavioral effects of cortisol in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372720"}
{"pmid": "4372721", "title": "\"Delayed\" iatrogenic diseases.", "content": "\"Delayed\" iatrogenic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372721"}
{"pmid": "4372722", "title": "Adenovirus type 11 epidemic conjunctivitis in Singapore.", "content": "Adenovirus type 11 epidemic conjunctivitis in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372722"}
{"pmid": "4372723", "title": "Epidemic haemorrhagic conjunctivitis associated with adenovirus type 11 in Taiwan.", "content": "Epidemic haemorrhagic conjunctivitis associated with adenovirus type 11 in Taiwan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372723"}
{"pmid": "4372724", "title": "Immunological tests in asymptomatic intestinal amoebiasis.", "content": "Immunological tests in asymptomatic intestinal amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372724"}
{"pmid": "4372725", "title": "Axenic cultivation of four strains of Entamoeba histolytica from liver abscesses.", "content": "Axenic cultivation of four strains of Entamoeba histolytica from liver abscesses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372725"}
{"pmid": "4372726", "title": "Dynamics of activity of redox enzymes in ontogenesis of Colorado beetle (Leptinotarsa decemlineata Say).", "content": "Dynamics of activity of redox enzymes in ontogenesis of Colorado beetle (Leptinotarsa decemlineata Say).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372726"}
{"pmid": "4372728", "title": "Oestrogen, headache and oral contraceptives.", "content": "Oestrogen, headache and oral contraceptives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372728"}
{"pmid": "4372729", "title": "Cervical synovial sarcoma in a young boy.", "content": "Cervical synovial sarcoma in a young boy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372729"}
{"pmid": "4372730", "title": "Liver aspiration cytology.", "content": "Liver aspiration cytology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372730"}
{"pmid": "4372731", "title": "Toxicity and carcinogenicity of some South African cycad (Encephalartos) species.", "content": "Toxicity and carcinogenicity of some South African cycad (Encephalartos) species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372731"}
{"pmid": "4372732", "title": "Inflammatory carcinoma of the breast.", "content": "Inflammatory carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372732"}
{"pmid": "4372733", "title": "Radiologically occult lung cancer. Report of 26 cases.", "content": "Radiologically occult lung cancer. Report of 26 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372733"}
{"pmid": "4372734", "title": "Results of treating malignant melanoma intralymphatically with radioactive isotopes.", "content": "Results of treating malignant melanoma intralymphatically with radioactive isotopes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372734"}
{"pmid": "4372735", "title": "Low cerebro-spinal fluid sugar associated with malignant glioma.", "content": "Low cerebro-spinal fluid sugar associated with malignant glioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372735"}
{"pmid": "4372736", "title": "Immune responses in patients with gliomas.", "content": "Immune responses in patients with gliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372736"}
{"pmid": "4372737", "title": "Structural changes during preparation of autogenous venous grafts.", "content": "Structural changes during preparation of autogenous venous grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372737"}
{"pmid": "4372739", "title": "X-ray diffraction analysis of quartz in lung tissue.", "content": "X-ray diffraction analysis of quartz in lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372739"}
{"pmid": "4372740", "title": "Immunological responsiveness in rats infected with the Soehner-Dmochowski murine sarcoma virus (MSV-SD).", "content": "Immunological responsiveness in rats infected with the Soehner-Dmochowski murine sarcoma virus (MSV-SD).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372740"}
{"pmid": "4372741", "title": "Antimicrobial therapy in experimental pseudomonas infection.", "content": "Antimicrobial therapy in experimental pseudomonas infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372741"}
{"pmid": "4372744", "title": "Effect of fulvine on pulmonary arteries and veins of the rat.", "content": "Effect of fulvine on pulmonary arteries and veins of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372744"}
{"pmid": "4372745", "title": "Response of patients receiving high dose beclomethasone dipropionate.", "content": "Response of patients receiving high dose beclomethasone dipropionate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372745"}
{"pmid": "4372746", "title": "Enhancement of plasminogen activator by vasopressin and adrenaline: a role of cyclic AMP?", "content": "Enhancement of plasminogen activator by vasopressin and adrenaline: a role of cyclic AMP?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372746"}
{"pmid": "4372747", "title": "Membrane fusion in the growth cone-microspike region of embryonic nerve cells undergoing axon elongation in cell culture.", "content": "Membrane fusion in the growth cone-microspike region of embryonic nerve cells undergoing axon elongation in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372747"}
{"pmid": "4372748", "title": "Fine structure of ocelli in sphinx moths.", "content": "Fine structure of ocelli in sphinx moths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372748"}
{"pmid": "4372749", "title": "A preliminary report on complex fibrillar aggregates in the gill epithelium of Panulirus interruptus (Randall).", "content": "A preliminary report on complex fibrillar aggregates in the gill epithelium of Panulirus interruptus (Randall).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372749"}
{"pmid": "4372750", "title": "Crystalline inclusions in the pituitary gonadotrophs of estrogen-primed, spayed rhesus monkeys (Macaca mulatta).", "content": "Crystalline inclusions in the pituitary gonadotrophs of estrogen-primed, spayed rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372750"}
{"pmid": "4372751", "title": "Effects of dibutyryl cyclic AMP on carbohydrate and lipid metabolism.", "content": "Effects of dibutyryl cyclic AMP on carbohydrate and lipid metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372751"}
{"pmid": "4372752", "title": "Obesity and pituitary lipolytic hormones.", "content": "Obesity and pituitary lipolytic hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372752"}
{"pmid": "4372754", "title": "Adenosine kinase from normal mouse erythrocytes and from Plasmodium chabaudi: partial purification and characterization.", "content": "Adenosine kinase from normal mouse erythrocytes and from Plasmodium chabaudi: partial purification and characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372754"}
{"pmid": "4372758", "title": "The production of blood cell stasis and endothelial damage in the blood vessels of chick embryos treated with ultrasound in a stationary wave field.", "content": "The production of blood cell stasis and endothelial damage in the blood vessels of chick embryos treated with ultrasound in a stationary wave field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372758"}
{"pmid": "4372760", "title": "Cyclic 3',5'-AMP-stimulated and non-stimulated phosphorylation of protein fractions from rat-liver cell sap on incubation with (gamma-32P)ATP.", "content": "Cyclic 3',5'-AMP-stimulated and non-stimulated phosphorylation of protein fractions from rat-liver cell sap on incubation with (gamma-32P)ATP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372760"}
{"pmid": "4372762", "title": "Active site phosphopeptides from pea seed nucleoside diphosphate kinase.", "content": "Active site phosphopeptides from pea seed nucleoside diphosphate kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372762"}
{"pmid": "4372761", "title": "(32P)phosphoryl transfer by endogenous protein kinase at the Ehrlich cell surface into extrinsic acceptor proteins.", "content": "(32P)phosphoryl transfer by endogenous protein kinase at the Ehrlich cell surface into extrinsic acceptor proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372761"}
{"pmid": "4372763", "title": "Innervation of the detrusor muscle and urethra.", "content": "Innervation of the detrusor muscle and urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372763"}
{"pmid": "4372764", "title": "Sphincter electromyography.", "content": "Sphincter electromyography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372764"}
{"pmid": "4372766", "title": "Symposium on renal lithiasis. Medical evaluation of urolithiasis. Etiologic aspects and diagnostic evaluation.", "content": "Symposium on renal lithiasis. Medical evaluation of urolithiasis. Etiologic aspects and diagnostic evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372766"}
{"pmid": "4372765", "title": "Symposium on renal lithiasis. Renal lithiasis in review.", "content": "Symposium on renal lithiasis. Renal lithiasis in review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372765"}
{"pmid": "4372767", "title": "Symposium on renal lithiasis. Urinary tract infection and renal lithiasis.", "content": "Symposium on renal lithiasis. Urinary tract infection and renal lithiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372767"}
{"pmid": "4372768", "title": "Genetic determinants of urologic disease.", "content": "Genetic determinants of urologic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372768"}
{"pmid": "4372770", "title": "Studies on the nucleic acid metabolism of renal tumour cells in vitro.", "content": "Studies on the nucleic acid metabolism of renal tumour cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372770"}
{"pmid": "4372771", "title": "Clostridial cystitis emphysematosa.", "content": "Clostridial cystitis emphysematosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372771"}
{"pmid": "4372772", "title": "Shedding patterns of herpes simplex virus and cytomegalovirus among chronic dialysis patients.", "content": "Shedding patterns of herpes simplex virus and cytomegalovirus among chronic dialysis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372772"}
{"pmid": "4372769", "title": "Secondary hyperparathyroidism in rats with experimentally induced pyelonephritis.", "content": "Secondary hyperparathyroidism in rats with experimentally induced pyelonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372769"}
{"pmid": "4372776", "title": "Spontaneous neoplasms in aging Gerbillinae. A summary of forty-four neoplasms.", "content": "Spontaneous neoplasms in aging Gerbillinae. A summary of forty-four neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372776"}
{"pmid": "4372777", "title": "An indirect haemagglutination test for the detection and assay of antibody to infectious bovine rhinotracheitis virus.", "content": "An indirect haemagglutination test for the detection and assay of antibody to infectious bovine rhinotracheitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372777"}
{"pmid": "4372778", "title": "Recent studies with etamiphyllin camsylate.", "content": "Recent studies with etamiphyllin camsylate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372778"}
{"pmid": "4372779", "title": "Airborne stability of swine vesicular disease virus.", "content": "Airborne stability of swine vesicular disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372779"}
{"pmid": "4372780", "title": "Interaction of phage P2 DNA with some fast-sedimenting host components during infection.", "content": "Interaction of phage P2 DNA with some fast-sedimenting host components during infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372780"}
{"pmid": "4372782", "title": "Temperature-sensitive mutants of herpes simplex virus type 1: isolation, complementation and partial characterization.", "content": "Temperature-sensitive mutants of herpes simplex virus type 1: isolation, complementation and partial characterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372782"}
{"pmid": "4372781", "title": "Phosphoproteins, structural components of rhabdoviruses.", "content": "Phosphoproteins, structural components of rhabdoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372781"}
{"pmid": "4372783", "title": "Control of transcription during the expression of the bluetongue virus genome.", "content": "Control of transcription during the expression of the bluetongue virus genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372783"}
{"pmid": "4372784", "title": "Polyoma virus proteins: a description of the structural proteins of the virion based on polyacrylamide gel electrophoresis and peptide analysis.", "content": "Polyoma virus proteins: a description of the structural proteins of the virion based on polyacrylamide gel electrophoresis and peptide analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372784"}
{"pmid": "4372785", "title": "Studies on the type C viral replication defect in MSV-transformed rat nonproducer variant clones.", "content": "Studies on the type C viral replication defect in MSV-transformed rat nonproducer variant clones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372785"}
{"pmid": "4372787", "title": "Electron microscopic studies of temperature-sensitive mutants of herpes simplex virus type 1.", "content": "Electron microscopic studies of temperature-sensitive mutants of herpes simplex virus type 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372787"}
{"pmid": "4372786", "title": "Cucumber mosaic virus-induced RNA polymerase: partial purification and properties of the template-free enzyme.", "content": "Cucumber mosaic virus-induced RNA polymerase: partial purification and properties of the template-free enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372786"}
{"pmid": "4372788", "title": "The persistence and expression of virus-specific DNA in revertants of Rous sarcoma virus-transformed BHK-21 cells.", "content": "The persistence and expression of virus-specific DNA in revertants of Rous sarcoma virus-transformed BHK-21 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372788"}
{"pmid": "4372789", "title": "Reversion and induction of Rous sarcoma virus expression in virus-transformed baby hamster kidney cells.", "content": "Reversion and induction of Rous sarcoma virus expression in virus-transformed baby hamster kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372789"}
{"pmid": "4372790", "title": "Isolation and characterization of a large molecular-weight polypeptide of herpes simplex virus type 1.", "content": "Isolation and characterization of a large molecular-weight polypeptide of herpes simplex virus type 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372790"}
{"pmid": "4372791", "title": "Glycoprotein fragment associated with vesicular stomatitis virus after proteolytic digestion.", "content": "Glycoprotein fragment associated with vesicular stomatitis virus after proteolytic digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372791"}
{"pmid": "4372812", "title": "Entero-bacterial formation of cyclohexylamine in rats ingesting cyclamate.", "content": "Entero-bacterial formation of cyclohexylamine in rats ingesting cyclamate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372812"}
{"pmid": "4372813", "title": "Kinetic experiments on the synergistic effect of NADH on microsomal drug oxidation.", "content": "Kinetic experiments on the synergistic effect of NADH on microsomal drug oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372813"}
{"pmid": "4372814", "title": "Commentary. EB virus, infectious mononucleosis, and cancer: the closing of the web.", "content": "Commentary. EB virus, infectious mononucleosis, and cancer: the closing of the web.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372814"}
{"pmid": "4372815", "title": "Expression of Epstein-Barr viral capsid, complement fixing, and nuclear antigens in stationary and exponential phase cultures.", "content": "Expression of Epstein-Barr viral capsid, complement fixing, and nuclear antigens in stationary and exponential phase cultures. Three continuous lymphoblastoid cell lines, 2 productive of nucleocapsids and 1 nonproductive line, were studied for their content of Epstein-Barr viral (EBV) antigens during transition from stationary to logarithmic phase growth. As a preliminary step, viable cells were separated from degenerating ones in discontinuous gradients of serum albumin. Viral capsid antigens were found in both living and dead cells of the 2 producer lines; however, complement fixing (CF) antigens and nuclear antigen were detected only in viable cell subpopulations. The content of antigen detectable in extracts of viable cells by complement fixation remained constant in replicating and resting cultures; further, all viable cells of the 3 lines demonstrated intranuclear antigen by anticomplement immunofluorescence in all stages of growth. In contrast, the proportion of cells with viral capsid antigen in the producer lines increased 7- to 24-fold following entry of resting populations into the phase of exponential growth.The results suggest that expression of viral capsid antigens is discontinuous and is initiated in response to events in log phase, possibly DNA synthesis or mitosis. Expression of the complement fixing and nuclear antigens in continuous in viable cells. These findings emphasize the intimate relationship of the CF and nuclear antigen to the transformed state and suggest that study of this antigen complex will shed light on the mechanisms of lymphocyte transformation by EBV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372815"}
{"pmid": "4372818", "title": "Measurement of human plasma renin substrate concentration by angiotensin I radioimmunoassay: a discussion of methodical problems.", "content": "Measurement of human plasma renin substrate concentration by angiotensin I radioimmunoassay: a discussion of methodical problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372818"}
{"pmid": "4372819", "title": "An evaluation of the diagnostic value of haptoglobin and transferrin levels in serum.", "content": "An evaluation of the diagnostic value of haptoglobin and transferrin levels in serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372819"}
{"pmid": "4372817", "title": "Growth hormone studies in patients with rheumatoid arthritis with or without glucocorticoid therapy.", "content": "Growth hormone studies in patients with rheumatoid arthritis with or without glucocorticoid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372817"}
{"pmid": "4372824", "title": "Comparative investigation on the activity of a synthetic corticotrophin (18-ACTH). A clinical trial.", "content": "Comparative investigation on the activity of a synthetic corticotrophin (18-ACTH). A clinical trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372824"}
{"pmid": "4372827", "title": "Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats in vivo.", "content": "Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372827"}
{"pmid": "4372833", "title": "Comparative study of the phosphatase activity in the semen of bovines (Bos bubalis and Bos taurus) in Egypt.", "content": "Comparative study of the phosphatase activity in the semen of bovines (Bos bubalis and Bos taurus) in Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372833"}
{"pmid": "4372834", "title": "Intracytoplasmic myocardial inclusions in chickens.", "content": "Intracytoplasmic myocardial inclusions in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372834"}
{"pmid": "4372837", "title": "Isolation, cultivation and characterization of a poxvirus from some horses in Kenya.", "content": "Isolation, cultivation and characterization of a poxvirus from some horses in Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372837"}
{"pmid": "4372838", "title": "Studies on bovine leukemia. I. Establishment of type C virus producing cell lines.", "content": "Studies on bovine leukemia. I. Establishment of type C virus producing cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372838"}
{"pmid": "4372842", "title": "An improved in vitro bioassay method for measuring luteinizing hormone (LH) activity using mouse Leydig cell preparations.", "content": "An improved in vitro bioassay method for measuring luteinizing hormone (LH) activity using mouse Leydig cell preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372842"}
{"pmid": "4372843", "title": "Cyclic AMP in isolated corpora lutea of the rat: influence of gonadotrophins and prostaglandins.", "content": "Cyclic AMP in isolated corpora lutea of the rat: influence of gonadotrophins and prostaglandins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372843"}
{"pmid": "4372845", "title": "Effect of pinealectomy on the 3H-5HT uptake of mast cells in the thyroid gland of the rat.", "content": "Effect of pinealectomy on the 3H-5HT uptake of mast cells in the thyroid gland of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372845"}
{"pmid": "4372844", "title": "Pharmacological mediators in asthma.", "content": "Pharmacological mediators in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372844"}
{"pmid": "4372846", "title": "Progressive myoclonic epilepsy with Lafora's bodies. A clinico-pathological study.", "content": "Progressive myoclonic epilepsy with Lafora's bodies. A clinico-pathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372846"}
{"pmid": "4372841", "title": "Letter: 'Latent type IV' hyperlipoproteinemia.", "content": "Letter: 'Latent type IV' hyperlipoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372841"}
{"pmid": "4372847", "title": "Histochemical changes in the rat spinal cord after exposure to 6-aminonicotinamide.", "content": "Histochemical changes in the rat spinal cord after exposure to 6-aminonicotinamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372847"}
{"pmid": "4372848", "title": "Effects of chloroquine on neurons of long-term cultures of peripheral and central nervous system. A light and electron microscope study.", "content": "Effects of chloroquine on neurons of long-term cultures of peripheral and central nervous system. A light and electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372848"}
{"pmid": "4372849", "title": "Morphological changes induced by ouabain in normal and neoplastic human glia in monolayer culture.", "content": "Morphological changes induced by ouabain in normal and neoplastic human glia in monolayer culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372849"}
{"pmid": "4372840", "title": "Insulin secretion in hyperlipoproteinemias.", "content": "Insulin secretion in hyperlipoproteinemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372840"}
{"pmid": "4372850", "title": "Infantile neuroaxonal dystrophy or Seitelberger's disease. IV. Autonomic nervous system involvement: electron microscopic study in two siblings.", "content": "Infantile neuroaxonal dystrophy or Seitelberger's disease. IV. Autonomic nervous system involvement: electron microscopic study in two siblings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372850"}
{"pmid": "4372851", "title": "Genetics and physiology of colour vision. II.", "content": "Genetics and physiology of colour vision. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372851"}
{"pmid": "4372852", "title": "Clinical aspects of neonatal hypoglycaemia.", "content": "Clinical aspects of neonatal hypoglycaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372852"}
{"pmid": "4372855", "title": "Induction of SV40-tumour immunity by SV40-transformed cells in diffusion chambers.", "content": "Induction of SV40-tumour immunity by SV40-transformed cells in diffusion chambers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372855"}
{"pmid": "4372853", "title": "Repression of hyaluronidase in Streptococcus mitis, ATCC 903.", "content": "Repression of hyaluronidase in Streptococcus mitis, ATCC 903.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372853"}
{"pmid": "4372854", "title": "The distribution of enzymes and bacteria in the small intestines of slaughter pigs.", "content": "The distribution of enzymes and bacteria in the small intestines of slaughter pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372854"}
{"pmid": "4372856", "title": "Decreased oncogenic potential of SV40-transformed cells grown in diffusion chambers intraperitoneally.", "content": "Decreased oncogenic potential of SV40-transformed cells grown in diffusion chambers intraperitoneally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372856"}
{"pmid": "4372857", "title": "The effect of lithium on blood pressure and on plasma renin substrate and renin in rats.", "content": "The effect of lithium on blood pressure and on plasma renin substrate and renin in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372857"}
{"pmid": "4372859", "title": "Pepstatin: lack of inhibition of the human renin-angiotensinogen reaction.", "content": "Pepstatin: lack of inhibition of the human renin-angiotensinogen reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372859"}
{"pmid": "4372858", "title": "Effect of lithium on glucagon-stimulated cyclic AMP excretion in rats.", "content": "Effect of lithium on glucagon-stimulated cyclic AMP excretion in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372858"}
{"pmid": "4372860", "title": "The relation of plasma renin activity to left ventricular hypertrophy and retinopathy in patients with arterial hypertension.", "content": "The relation of plasma renin activity to left ventricular hypertrophy and retinopathy in patients with arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372860"}
{"pmid": "4372861", "title": "Lp(a) lipoprotein and pre-beta1-lipoprotein in young adults.", "content": "Lp(a) lipoprotein and pre-beta1-lipoprotein in young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372861"}
{"pmid": "4372862", "title": "A theoretical treatment of the problem of virion attachment and infection of the host cell.", "content": "A theoretical treatment of the problem of virion attachment and infection of the host cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372862"}
{"pmid": "4372863", "title": "Metabolic effect of interferon preparations and some interferon inducers: activation of adenylate cyclase system.", "content": "Metabolic effect of interferon preparations and some interferon inducers: activation of adenylate cyclase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372863"}
{"pmid": "4372864", "title": "Further evidences that priming is a non-antiviral function of interferon.", "content": "Further evidences that priming is a non-antiviral function of interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372864"}
{"pmid": "4372865", "title": "\"Plexiform vermicellar arrays\" in human cytomegalovirus-infected WI-38 human embryonic fibroblast cells.", "content": "\"Plexiform vermicellar arrays\" in human cytomegalovirus-infected WI-38 human embryonic fibroblast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372865"}
{"pmid": "4372869", "title": "The rehabilitation of addicts.", "content": "The rehabilitation of addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372869"}
{"pmid": "4372870", "title": "The anion-binding functions of transferrin.", "content": "The anion-binding functions of transferrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372870"}
{"pmid": "4372871", "title": "Calcium binding to elastin.", "content": "Calcium binding to elastin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372871"}
{"pmid": "4372872", "title": "Cellular effects of lead.", "content": "Cellular effects of lead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372872"}
{"pmid": "4372873", "title": "X-ray photoelectron spectroscopic studies of biological materials: metal ion protein binding and other analytical applications.", "content": "X-ray photoelectron spectroscopic studies of biological materials: metal ion protein binding and other analytical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372873"}
{"pmid": "4372874", "title": "The child with acute leukemia.", "content": "The child with acute leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372874"}
{"pmid": "4372875", "title": "Development of a dust sampling system for hardrock mines based on gravimetric and quartz assessment.", "content": "Development of a dust sampling system for hardrock mines based on gravimetric and quartz assessment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372875"}
{"pmid": "4372876", "title": "X-ray diffraction determination of alpha-quartz in respirable and total dust samples from sand-blasting operations.", "content": "X-ray diffraction determination of alpha-quartz in respirable and total dust samples from sand-blasting operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372876"}
{"pmid": "4372877", "title": "Relationship between exposure to asbestos, collagen formation, ferruginous bodies, and carcinoma.", "content": "Relationship between exposure to asbestos, collagen formation, ferruginous bodies, and carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372877"}
{"pmid": "4372879", "title": "Gastrointestinal malacoplakia. Report of a case and a review of the literature.", "content": "Gastrointestinal malacoplakia. Report of a case and a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372879"}
{"pmid": "4372878", "title": "Comparative evaluation of a partial thromboplastin reagent containing a non-settling, particulate activator.", "content": "Comparative evaluation of a partial thromboplastin reagent containing a non-settling, particulate activator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372878"}
{"pmid": "4372880", "title": "Immunoglobulin and autoantibody response in acute and chronic liver disease.", "content": "Immunoglobulin and autoantibody response in acute and chronic liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372880"}
{"pmid": "4372881", "title": "Reappraisal of the role of insulin in hypertriglyceridemia.", "content": "Reappraisal of the role of insulin in hypertriglyceridemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372881"}
{"pmid": "4372882", "title": "The hormones of the hypothalamus.", "content": "The hormones of the hypothalamus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372882"}
{"pmid": "4372883", "title": "Hepatic abscess: changes in clinical, bacteriologic and therapeutic aspects.", "content": "Hepatic abscess: changes in clinical, bacteriologic and therapeutic aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372883"}
{"pmid": "4372884", "title": "Fasting hypoglycemia, hypercalcemia and hyperprolactinemia. Multiple endocrine neoplasia, type 1?", "content": "Fasting hypoglycemia, hypercalcemia and hyperprolactinemia. Multiple endocrine neoplasia, type 1?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372884"}
{"pmid": "4372885", "title": "Parathyroid carcinoma in familial hyperparathyroidism.", "content": "Parathyroid carcinoma in familial hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372885"}
{"pmid": "4372886", "title": "Breast cancer in men. Report illustrating the value of endocrine ablation.", "content": "Breast cancer in men. Report illustrating the value of endocrine ablation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372886"}
{"pmid": "4372888", "title": "Adenoid cystic carcinoma of the cervix presenting as a primary bronchial neoplasm.", "content": "Adenoid cystic carcinoma of the cervix presenting as a primary bronchial neoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372888"}
{"pmid": "4372887", "title": "The \"viruses of love\" and cancer.", "content": "The \"viruses of love\" and cancer. A review of recent results of research into Herpesvirus is presented and a tentative association with cervical cancer is proposed.  2 types of the virus have been identified, HSV-1 which causes fever blisters or lip sores and HSV-2 which causes genital lesions.  The structure and composition of the virus is described.  In addition, mechanisms of productive and nonproductive infection at the cellular level are reviewed.  The pathogenesis of the HSV-1 and HSV-2 infections varies according to previous exposure, whether the patient is in a compromised medical condition and for newborns.  Many primary infections are subclinical, however when apparent are more severe than recurrent cases.  Most infections are localized to superficial areas of the skin or mucous membranes, which may be due to the virus' inability to spread through the connective tissue, variation in tissue susceptibility, proclivity of dissemination through blood or nerves and immune responses.  Primary oral infections range from inapparent to severe gingivostomatitis with extensive ulceration of the mouth, tongue and gum, fever, and adenopathy.  The occular conditions include conjunctivitis, cataracts, iridocyclitis, and panuveitis.  The genital infection occurs on the cervix and external genitalia in women and the penis, urethra, prostate and seminal vesicle in men.  Most cases of neonatal disease are caused by HSV-2.  The neurologic manifestations associated with the virus include encephalitis, meningitis and myelitis.  The recurrent disease consists of localized vesicular lesions caused by various stress factors.  It is suspected that for most recurrences the virus has persisted in the interim in a noninfectious form close to or at the site of the recurrency.  Data from several studies support this hypothesis.  Research into the mechanism of virus persistence and recurrence is focusing on the host cell and the role of immune factors.  Diagnosis is largely clinical although some laboratory aids have been useful.  Among the drugs used in prevention and therapy, the application of vital dye such as neutral red or proflavine, followed by exposure to light has been successful with recurrent lesions.  Research is warranted into the use of fever therapy and interferon.  Recently Hespesvirus has been associated with cancer in at least 6 cases.  Interpretation of data from animal as well as human studies is suggestive of a link but other explanatory factors have not been ruled out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372887"}
{"pmid": "4372889", "title": "The use of a radioimmunoassay specific for human chorionic gonadotropin in patients with molar pregnancy and gestational trophoblastic disease.", "content": "The use of a radioimmunoassay specific for human chorionic gonadotropin in patients with molar pregnancy and gestational trophoblastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372889"}
{"pmid": "4372890", "title": "Ultrastructure of sclerosing hemangioma.", "content": "Ultrastructure of sclerosing hemangioma. Specimens from 9 patients with the varying histopathologic patterns of sclerosing hemangioma were studied by electron microscopy. Not only were there numerous identifiable vascular spaces, but many of the cells had the ultrastructural characteristics of endothelial cells whether they were lining vascular spaces, forming organoid structures or were isolated. The Weibel-Palade bodies served as a marker for endothelial cells. They are rod-shaped, with a length up to 2 mu and a diameter up to .1 mu, and contain a tubular substructure, the diameter of the individual tubules being 150 [unk]. Our findings clearly support Gross and Wolbach's theory that this group of lesions is of endothelial origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372890"}
{"pmid": "4372891", "title": "Experimental cytomegalovirus ophthalmitis.", "content": "Experimental cytomegalovirus ophthalmitis. Cytomegalovirus can produce a severe necrotizing chorioretinitis in patients on immunosuppressive therapy and infants born with congenital cytomegaloviral inclusion disease. To study the effect of cytomegalovirus on the eye, murine cytomegalovirus was injected into the eyes of nonimmunosuppressed Swiss CD-1 weanling mice. The eyes were then prepared for virus titer, as well as light and electron microscopy at variable periods after inoculation (1 to 28 days). From days 2 to 6, the hallmarks of cytomegalovirus infection, intranuclear and intracytoplasmic viral inclusions, were evident within cytomegalic cells. The major site of reaction was in the uveal tract, where necrosis and inflammation were prominent. Viral particles budding through the nuclear membranes into the perinuclear cisternae and vacuoles with viral particles could be seen in the cytoplasm of infected cells. In lesions older than 2 weeks, only a mild mixed inflammatory infiltrate and fibrosis were observed. Morphologic alterations unaccompanied by inflammation occurred in the outer sensory retina overlying infected retinal pigment epithelial cells. Multiple necrotic foci with inclusion-bearing cells in the liver indicated the systemic spread of virus from the eye. The titer of virus recovered from the eye peaked at day 4 and then declined to low levels, but infectious virus could still be isolated at day 28, even though viral particles were not seen morphologically at or after day 14. Many of the alterations seen in the model resemble those found in the human cytomegaloviral ophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372891"}
{"pmid": "4372892", "title": "Male advancement in prenatal hand development.", "content": "Male advancement in prenatal hand development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372892"}
{"pmid": "4372893", "title": "Carbohydrate metabolism of heat-acclimated hamsters. IV. Hormonal control.", "content": "Carbohydrate metabolism of heat-acclimated hamsters. IV. Hormonal control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372893"}
{"pmid": "4372894", "title": "Effects of parathyroidectomy and cyclic AMP on renal transport of phosphate, calcium, and magnesium.", "content": "Effects of parathyroidectomy and cyclic AMP on renal transport of phosphate, calcium, and magnesium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372894"}
{"pmid": "4372895", "title": "Potassium deficiency in rats with hereditary diabetes insipidus.", "content": "Potassium deficiency in rats with hereditary diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372895"}
{"pmid": "4372896", "title": "Relation of fibrinogen secretion (synthesis) to ACTH dose.", "content": "Relation of fibrinogen secretion (synthesis) to ACTH dose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372896"}
{"pmid": "4372897", "title": "ACTH stimulation of fibrinogen biosynthesis.", "content": "ACTH stimulation of fibrinogen biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372897"}
{"pmid": "4372898", "title": "Membrane depolarization, cyclic AMP, and glycerol release by brown adipose tissue.", "content": "Membrane depolarization, cyclic AMP, and glycerol release by brown adipose tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372898"}
{"pmid": "4372899", "title": "Catecholamine receptor function in depressed patients.", "content": "Catecholamine receptor function in depressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372899"}
{"pmid": "4372900", "title": "Cultural aspects of psychotherapy.", "content": "Cultural aspects of psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372900"}
{"pmid": "4372902", "title": "Artificial slow-flow carotid angiography with tumors of the glomus jugulare and of the carotid body.", "content": "Artificial slow-flow carotid angiography with tumors of the glomus jugulare and of the carotid body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372902"}
{"pmid": "4372901", "title": "The use of multiple radionuclide imaging to differentiate the focal intrahepatic lesion.", "content": "The use of multiple radionuclide imaging to differentiate the focal intrahepatic lesion. Thirty-five patients with various focal intrahepatic lesions were evaluated with multiple radionuclides. Comparison of the blood pool scans with angiography and histology demonstrated an excellent correlation of these studies. Diagnostic accuracy was improved by separating the blood and pool scans into 3 categories. Each category suggested, at most, one further study to provide specific diagnostic information. Thus, by utilizing 3 radiopharmaceuticals, one can be more specific in preoperative diagnoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372901"}
{"pmid": "4372904", "title": "Islet cell tumors of the pancreas.", "content": "Islet cell tumors of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372904"}
{"pmid": "4372903", "title": "In vitro cultivation of Plasmodium falciparum at high parasitemia.", "content": "In vitro cultivation of Plasmodium falciparum at high parasitemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372903"}
{"pmid": "4372905", "title": "Correlation of circulating serum antibody to the histologic findings in breast cancer.", "content": "Correlation of circulating serum antibody to the histologic findings in breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372905"}
{"pmid": "4372907", "title": "Determination of 5-phosphoribosyl 1-pyrophosphate in mouse liver.", "content": "Determination of 5-phosphoribosyl 1-pyrophosphate in mouse liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372907"}
{"pmid": "4372908", "title": "Continuous pH-stat titration method for the assay of lipoprotein lipase activity in vitro.", "content": "Continuous pH-stat titration method for the assay of lipoprotein lipase activity in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372908"}
{"pmid": "4372909", "title": "Identification of fatty acids by GC-MS using polar siloxane liquid phases.", "content": "Identification of fatty acids by GC-MS using polar siloxane liquid phases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372909"}
{"pmid": "4372912", "title": "Persistent viremia after regression of primary virus-induced feline fibrosarcomas.", "content": "Persistent viremia after regression of primary virus-induced feline fibrosarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372912"}
{"pmid": "4372911", "title": "The effect of ketamine on regional cerebral blood flow in man.", "content": "The effect of ketamine on regional cerebral blood flow in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372911"}
{"pmid": "4372913", "title": "Duration of immunity in recycled turkey breeder hens vaccinated with a single dose of live avian encephalomyelitis virus vaccine.", "content": "Duration of immunity in recycled turkey breeder hens vaccinated with a single dose of live avian encephalomyelitis virus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372913"}
{"pmid": "4372906", "title": "Clinical evaluation of the most frequently used analgetics: morphine, pethidine, pentazocine, fentanyl and noramidopyrine (pyralgin).", "content": "Clinical evaluation of the most frequently used analgetics: morphine, pethidine, pentazocine, fentanyl and noramidopyrine (pyralgin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372906"}
{"pmid": "4372914", "title": "Early in utero infection of porcine embryos and fetuses with SMEDI (entero-) viruses: mortality, antibody development, and viral persistence.", "content": "Early in utero infection of porcine embryos and fetuses with SMEDI (entero-) viruses: mortality, antibody development, and viral persistence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372914"}
{"pmid": "4372915", "title": "Pathogenic properties of six bovine picornavirus isolates in mice.", "content": "Pathogenic properties of six bovine picornavirus isolates in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372915"}
{"pmid": "4372916", "title": "Effects of cord factor on microsomal enzymes.", "content": "Effects of cord factor on microsomal enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372916"}
{"pmid": "4372917", "title": "Immune response in persistent infection. Further studies on persistent respiratory infection in man with para-influenza type 3 virus.", "content": "Immune response in persistent infection. Further studies on persistent respiratory infection in man with para-influenza type 3 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372917"}
{"pmid": "4372910", "title": "A new approach to the study of four nondepolarizing relaxants in man.", "content": "A new approach to the study of four nondepolarizing relaxants in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372910"}
{"pmid": "4372918", "title": "Effect of angiotensin and ACTH on gastric secretion.", "content": "Effect of angiotensin and ACTH on gastric secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372918"}
{"pmid": "4372919", "title": "Diagnostic value of thyrotrophin-releasing hormone in pituitary and hypothalamic diseases. Assessment of thyrotrophin and prolactin secretion in 100 patients.", "content": "Diagnostic value of thyrotrophin-releasing hormone in pituitary and hypothalamic diseases. Assessment of thyrotrophin and prolactin secretion in 100 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372919"}
{"pmid": "4372920", "title": "Hepatocellular carcinoma and partial deficiency of alpha-1 antitrypsin (MZ).", "content": "Hepatocellular carcinoma and partial deficiency of alpha-1 antitrypsin (MZ).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372920"}
{"pmid": "4372921", "title": "Emphysema, cirrhosis, and hepatoma with alpha-1 antitrypsin deficiency.", "content": "Emphysema, cirrhosis, and hepatoma with alpha-1 antitrypsin deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372921"}
{"pmid": "4372922", "title": "Letter: Parainfluenza virus type 3 isolated in a case of bloody diarrhea.", "content": "Letter: Parainfluenza virus type 3 isolated in a case of bloody diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372922"}
{"pmid": "4372923", "title": "Digitonin as an uncoupler of the partial reactions of Na+, K+-ATPase.", "content": "Digitonin as an uncoupler of the partial reactions of Na+, K+-ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372923"}
{"pmid": "4372924", "title": "Analysis of Na+, K+ and nucleotide interactions in terms of a heterotropic relaxation model for (Na+-K+)-ATPase.", "content": "Analysis of Na+, K+ and nucleotide interactions in terms of a heterotropic relaxation model for (Na+-K+)-ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372924"}
{"pmid": "4372925", "title": "Studies of the effects of 2H2O on Na+, K+-ATPase.", "content": "Studies of the effects of 2H2O on Na+, K+-ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372925"}
{"pmid": "4372926", "title": "The relationship of the K+-activated phosphatase to the Na+,K+-ATPase.", "content": "The relationship of the K+-activated phosphatase to the Na+,K+-ATPase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372926"}
{"pmid": "4372927", "title": "The effects of Ca2+ on ATPase and phosphatase activities of erythrocyte membranes.", "content": "The effects of Ca2+ on ATPase and phosphatase activities of erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372927"}
{"pmid": "4372928", "title": "The effects of antibodies to Na+, K+-ATPase on the reactions catalyzed by the enzyme.", "content": "The effects of antibodies to Na+, K+-ATPase on the reactions catalyzed by the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372928"}
{"pmid": "4372929", "title": "Na+, K+ exchange and Na+, Na+ exchange in the giant axon of the squid.", "content": "Na+, K+ exchange and Na+, Na+ exchange in the giant axon of the squid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372929"}
{"pmid": "4372930", "title": "Action of methanethiol on Na+, K+-ATPase: implications for hepatic coma.", "content": "Action of methanethiol on Na+, K+-ATPase: implications for hepatic coma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372930"}
{"pmid": "4372931", "title": "Mechanism of the effects of lipid phase transitions on the Na+, K+-ATPase, and the role of protein conformational changes.", "content": "Mechanism of the effects of lipid phase transitions on the Na+, K+-ATPase, and the role of protein conformational changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372931"}
{"pmid": "4372932", "title": "Ouabain sensitivity of the Na+, K+-ATPase from rat neonatal and human fetal and adult heart.", "content": "Ouabain sensitivity of the Na+, K+-ATPase from rat neonatal and human fetal and adult heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372932"}
{"pmid": "4372935", "title": "Antibody levels to multiple viral antigens in systemic lupus erythematosus and some other connective tissue diseases.", "content": "Antibody levels to multiple viral antigens in systemic lupus erythematosus and some other connective tissue diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372935"}
{"pmid": "4372936", "title": "Regulation of enzyme activity during differentiation in Dictyostelium discoideum.", "content": "Regulation of enzyme activity during differentiation in Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372936"}
{"pmid": "4372937", "title": "Inclusion bodies of prokaryotes.", "content": "Inclusion bodies of prokaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372937"}
{"pmid": "4372938", "title": "Slow virus diseases.", "content": "Slow virus diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372938"}
{"pmid": "4372939", "title": "Cyclic AMP in prokaryotes.", "content": "Cyclic AMP in prokaryotes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372939"}
{"pmid": "4372942", "title": "Studies on photosystem I. Characteristics of \"310 material\" isolated from spinach chloroplasts.", "content": "Studies on photosystem I. Characteristics of \"310 material\" isolated from spinach chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372942"}
{"pmid": "4372943", "title": "Metabolism of vitamin D3 in the chick embryo.", "content": "Metabolism of vitamin D3 in the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372943"}
{"pmid": "4372945", "title": "Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes.", "content": "Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372945"}
{"pmid": "4372944", "title": "Effect of trypsin, phospholipases, and membrane-impermeable reagents on the uptake of palmitic acid by isolated rat liver cells.", "content": "Effect of trypsin, phospholipases, and membrane-impermeable reagents on the uptake of palmitic acid by isolated rat liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372944"}
{"pmid": "4372946", "title": "The effect of trypsin treatment on rabbit muscle phosphofructokinase.", "content": "The effect of trypsin treatment on rabbit muscle phosphofructokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372946"}
{"pmid": "4372947", "title": "A new ternary complex between horse liver alcohol dehydrogenase, NAD+, and acetone.", "content": "A new ternary complex between horse liver alcohol dehydrogenase, NAD+, and acetone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372947"}
{"pmid": "4372948", "title": "A two-step procedure for purification of papain from extract of papaya latex.", "content": "A two-step procedure for purification of papain from extract of papaya latex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372948"}
{"pmid": "4372949", "title": "Distribution of liver plasma membrane 5' nucleotidase as indicated by its reaction with anti-plasma membrane serum.", "content": "Distribution of liver plasma membrane 5' nucleotidase as indicated by its reaction with anti-plasma membrane serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372949"}
{"pmid": "4372950", "title": "Analysis of the ATP-induced conformational changes in sarcoplasmic reticulum.", "content": "Analysis of the ATP-induced conformational changes in sarcoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372950"}
{"pmid": "4372951", "title": "The reversal of experimental porphyria and the prevention of induction of hepatic mixed-function oxidase by acetate.", "content": "The reversal of experimental porphyria and the prevention of induction of hepatic mixed-function oxidase by acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372951"}
{"pmid": "4372952", "title": "Studies on a HCO3 minus-stimulated ATPase and carbonic anhydrase system in rat liver lysosomes.", "content": "Studies on a HCO3 minus-stimulated ATPase and carbonic anhydrase system in rat liver lysosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372952"}
{"pmid": "4372953", "title": "In vivo changes of cellulose, trehalose and glycogen during differentiation of Dictyostelium discoideum.", "content": "In vivo changes of cellulose, trehalose and glycogen during differentiation of Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372953"}
{"pmid": "4372954", "title": "Growth in children with 45,XO Turner's syndrome.", "content": "Growth in children with 45,XO Turner's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372954"}
{"pmid": "4372955", "title": "Plasma renin activity in acute poststreptococcal glomerulonephritis and the haemolytic-uraemic syndrome.", "content": "Plasma renin activity in acute poststreptococcal glomerulonephritis and the haemolytic-uraemic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372955"}
{"pmid": "4372956", "title": "Dose-response basis for settling a quartz threshold limit value: a new, simple formula for calculating the \"lifetime dose\" of quartz.", "content": "Dose-response basis for settling a quartz threshold limit value: a new, simple formula for calculating the \"lifetime dose\" of quartz.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372956"}
{"pmid": "4372958", "title": "Studies on some pathogenic strains of free-living amoebae isolated from lakes in Poland.", "content": "Studies on some pathogenic strains of free-living amoebae isolated from lakes in Poland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372958"}
{"pmid": "4372960", "title": "Clinical application of cytochrome a(plus a3) assay of mitochondria from liver specimens: an aid in determining metabolic tolerance of liver remnant for hepatic resection.", "content": "Clinical application of cytochrome a(plus a3) assay of mitochondria from liver specimens: an aid in determining metabolic tolerance of liver remnant for hepatic resection. Measurement of cytochrome a(+a(3)) contents in liver mitochondria was made on 52 biopsy specimens of patients with liver tumor. Patients having higher cytochrome a(+a(3)) contents in mitochondria from remaining liver than those of normal human liver mitochondria could survive well major liver resections whether or not associated with liver cirrhosis. However, patients with cytochrome a(+a(3)) contents less than 0.5 x 10(-10) moles per mg protein showed a high rate of postoperative complication (80%) and death (40%) in spite of minor operation. In routinely used liver function tests such as serum albumin, A/G ratio, SGOT, total bilirubin, prothrombin time, BSP and TTT, there were no significant differences between patients with cytochrome a(+a(3)) contents more than 0.5 x 10(-10) moles per mg protein and those less than 0.5. The results indicate that routine laboratory studies do not have much diagnostic value in estimation of a marked decrease of mitochondrial cytochrome a(+a(3)) contents. It is suggested that the measurements of cytochrome a(+a(3)) of the remnant liver should be done prior to a contemplated major resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372960"}
{"pmid": "4372962", "title": "Chemotherapy for adenocarcinoma and alveolar cell carcinoma of the lung.", "content": "Chemotherapy for adenocarcinoma and alveolar cell carcinoma of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372962"}
{"pmid": "4372961", "title": "The role of early open lung biopsy in the diagnosis and treatment of Pneumocystis carinii pneumonia.", "content": "The role of early open lung biopsy in the diagnosis and treatment of Pneumocystis carinii pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372961"}
{"pmid": "4372963", "title": "Hydrocortisone suppression test for Cushing syndrome. Therapy with anticonvulsants.", "content": "Hydrocortisone suppression test for Cushing syndrome. Therapy with anticonvulsants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372963"}
{"pmid": "4372965", "title": "Nitrogen metabolism and ultrastructure in Anabaena cylindrica. II. The effect of molybdenum and vanadium.", "content": "Nitrogen metabolism and ultrastructure in Anabaena cylindrica. II. The effect of molybdenum and vanadium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372965"}
{"pmid": "4372966", "title": "A study of sporophore development in the myxomycete Protophysarum phloiogenum.", "content": "A study of sporophore development in the myxomycete Protophysarum phloiogenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372966"}
{"pmid": "4372967", "title": "Hyphal tips of wild-type and spreading colonial mutants of Neurospora crassa.", "content": "Hyphal tips of wild-type and spreading colonial mutants of Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372967"}
{"pmid": "4372970", "title": "Quantitative studies by electron microscopy on the sex-difference and the change during the oestrous cycle in the mouse anterior pituitary.", "content": "Quantitative studies by electron microscopy on the sex-difference and the change during the oestrous cycle in the mouse anterior pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372970"}
{"pmid": "4372977", "title": "Xerosialography.", "content": "Xerosialography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372977"}
{"pmid": "4372975", "title": "Opsoclonus associated with an intracranial tumor. A clinicopathologic case report.", "content": "Opsoclonus associated with an intracranial tumor. A clinicopathologic case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372975"}
{"pmid": "4372976", "title": "Pullularia corneal ulcer.", "content": "Pullularia corneal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372976"}
{"pmid": "4372979", "title": "Fibrous histiocytomas of the nose and paranasal sinuses.", "content": "Fibrous histiocytomas of the nose and paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372979"}
{"pmid": "4372978", "title": "Granular cell myoblastoma of the trachea.", "content": "Granular cell myoblastoma of the trachea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372978"}
{"pmid": "4372981", "title": "Regional odontodysplasia. A review and a report of two cases.", "content": "Regional odontodysplasia. A review and a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372981"}
{"pmid": "4372982", "title": "inositol phosphate phosphatases of microbiological origin. Some properties of the partially purified phosphatases of Aspergillus ficuum NRRL 3135.", "content": "inositol phosphate phosphatases of microbiological origin. Some properties of the partially purified phosphatases of Aspergillus ficuum NRRL 3135.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372982"}
{"pmid": "4372986", "title": "The limbic system: an interface.", "content": "The limbic system: an interface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372986"}
{"pmid": "4372988", "title": "A new method for propagation of HVJ (Sendai virus) in vitro: high sensitivity and productivity in spreading cultures of fragmented chorioallantoic membrane of chick embryos.", "content": "A new method for propagation of HVJ (Sendai virus) in vitro: high sensitivity and productivity in spreading cultures of fragmented chorioallantoic membrane of chick embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372988"}
{"pmid": "4372989", "title": "Chemical and immunological studies of liver microsomes from mouse mutants with ultrastructurally abnormal hepatic endoplasmic reticulum.", "content": "Chemical and immunological studies of liver microsomes from mouse mutants with ultrastructurally abnormal hepatic endoplasmic reticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372989"}
{"pmid": "4372990", "title": "Anti-anabolic effects of adenosine 3':5'-cyclic monophosphate. Inhibition of protein synthesis.", "content": "Anti-anabolic effects of adenosine 3':5'-cyclic monophosphate. Inhibition of protein synthesis. 1. Evidence is presented that cyclic AMP inhibits the incorporation of l-[4,5-(3)H]leucine into protein in a cell-free system from rat liver. This inhibition occurs after aminoacyl-tRNA formation. 2. Microsomal fractions, isolated after the incubation of postmitochondrial supernatant with cyclic AMP and ATP, show a diminished ability to synthesize protein. Both cyclic AMP and ATP are required for this effect. 3. A possible physiological role for the anti-anabolic action of cyclic AMP is discussed in terms of the control of gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372990"}
{"pmid": "4372992", "title": "The effects of acetylcolletotrichin on the mitochondrial respiratory chain.", "content": "The effects of acetylcolletotrichin on the mitochondrial respiratory chain. 1. Acetylcolletotrichin is a phytotoxic compound that has been isolated from the culture medium of the fungus Colletotrichum capsici (Grove et al., 1966). 2. With isolated liver and kidney mitochondria acetylcolletotrichin markedly inhibited the oxidation of succinate and those substrates with NAD-linked dehydrogenases, but did not inhibit the oxidation of ascorbate in the presence of tetramethyl-p-phenylenediamine. In this respect its action was similar to that of antimycin A. 3. Acetylcolletotrichin differed from antimycin in that, even at high concentrations which produced a maximal inhibitory effect, its action was partially reversed by uncoupling agents. Also acetylcolletotrichin had no detectable effect on the oxidative activity of blowfly flight-muscle mitochondria and was not very effective with heart mitochondria. 4. Acetylcolletotrichin inhibited the oxidative activity of liver mitochondria more markedly when respiration was stimulated by ADP together with phosphate and was less effective when respiration was stimulated by uncoupling agents. 5. There was an unusual interaction between the succinate oxidation system and the oxidation of glutamate together with malate. Thus, glutamate together with malate, even in the presence of rotenone, markedly decreased the effectiveness of acetylcolletotrichin in inhibiting succinate oxidation. 6. These effects were paralleled in the observed redox changes of cytochrome c. 7. The unusual behaviour of the cytochromes b in the presence of acetylcolletotrichin is described, and it is suggested tentatively that this inhibitor acts between cytochromes b with absorption maxima at 30 degrees C of approximately 560 and 565nm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372992"}
{"pmid": "4372991", "title": "Nitrogen metabolism in the isolated perfused rat liver. Nitrogen balance, redox state and rates of proteolysis.", "content": "Nitrogen metabolism in the isolated perfused rat liver. Nitrogen balance, redox state and rates of proteolysis. Nitrogen balances were measured in isolated perfused rat livers in the presence and absence of nitrogen donors. In all instances the balance apparently was incomplete. The expression [alanine][alpha-oxoglutarate]/[pyruvate][glutamate] remained fairly constant under the metabolic conditions studied, indicating that it may be at near-equilibrium. The source of the extra nitrogen seems to be derived from increased hepatic proteolysis. The addition of a nitrogen donor to the perfusate arrested proteolysis, as did the addition of pyruvate. The free mitochondrial [NAD(+)]/[NADH] ratio, calculated from the glutamate dehydrogenase and beta-hydroxybutyrate dehydrogenase reactants, showed similar values and exhibited parallel changes under most metabolic situations studied. These results suggest that, under the reported experimental conditions, both dehydrogenases share a common mitochondrial NAD pool. Glutamate dehydrogenase plays an important role in hepatic nitrogen metabolism in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372991"}
{"pmid": "4372994", "title": "Phosphodiesterases in human tissues. I. Identification and separation of enzymes active on bis(p-nitrophenyl)phosphate.", "content": "Phosphodiesterases in human tissues. I. Identification and separation of enzymes active on bis(p-nitrophenyl)phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372994"}
{"pmid": "4372995", "title": "Phosphodiesterases in human tissues. II. Decreased hydrolysis of synthetic substrate by tissues from patients with the Niemann-Pick syndrome.", "content": "Phosphodiesterases in human tissues. II. Decreased hydrolysis of synthetic substrate by tissues from patients with the Niemann-Pick syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372995"}
{"pmid": "4372984", "title": "Interferon production by strains of herpesvirus associated with Marek's disease.", "content": "Interferon production by strains of herpesvirus associated with Marek's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372984"}
{"pmid": "4372983", "title": "Preparation of fowl pox vaccine on chicken-embryo-dermis cell culture.", "content": "Preparation of fowl pox vaccine on chicken-embryo-dermis cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372983"}
{"pmid": "4372997", "title": "UDP glucose-4 epimerase from Saccharomyces fragilis: interaction with sugar phosphates at an effector site.", "content": "UDP glucose-4 epimerase from Saccharomyces fragilis: interaction with sugar phosphates at an effector site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372997"}
{"pmid": "4372993", "title": "Biochemical effects of diquat and paraquat. Disturbance of the control of corticosteroid synthesis in rat adrenal and subsequent effects on the control of liver glycogen utilization.", "content": "Biochemical effects of diquat and paraquat. Disturbance of the control of corticosteroid synthesis in rat adrenal and subsequent effects on the control of liver glycogen utilization. 1. Administration of diquat (NN'-ethylene-2,2'-bipyridilium) or paraquat (NN'-dimethyl-4,4'-bipyridilium) prevents the normal depletion of liver glycogen in starved rats. 2. There is an increase in blood glucose, which returns to normal values after approx. 7h. 3. After administration of diquat or paraquat, plasma corticosteroids increase to very high concentrations and remain high for at least 24h, but plasma ACTH (adrenocorticotrophin) is only increased for 4h. 4. Adrenal cyclic AMP is considerably increased after administration of diquat and remains significantly higher than control values for at least 24h. 5. It is suggested that diquat and paraquat increase the response of the adrenal cortex to ACTH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372993"}
{"pmid": "4372985", "title": "Factors influencing growth of Mycoplasma synoviae.", "content": "Factors influencing growth of Mycoplasma synoviae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372985"}
{"pmid": "4372996", "title": "Role of superoxide radical in mitochondrial dehydrogenase reactions.", "content": "Role of superoxide radical in mitochondrial dehydrogenase reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372996"}
{"pmid": "4372998", "title": "Insulin degradation in insulinoma: evidence for the occurrence of an inactive form of glutathione-insulin transhydrogenase and for the absence of insulin A and B chains degrading protease(s).", "content": "Insulin degradation in insulinoma: evidence for the occurrence of an inactive form of glutathione-insulin transhydrogenase and for the absence of insulin A and B chains degrading protease(s).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372998"}
{"pmid": "4372999", "title": "Maintenance of the energy charge in the presence of large decreases in the total adenylate pool of Escherichia coli and concurrent changes in glucose-6-p, fructose-p2 and glycogen synthesis.", "content": "Maintenance of the energy charge in the presence of large decreases in the total adenylate pool of Escherichia coli and concurrent changes in glucose-6-p, fructose-p2 and glycogen synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4372999"}
{"pmid": "4373000", "title": "The meta-cleavage of catechol by a thermophilic Bacillus species.", "content": "The meta-cleavage of catechol by a thermophilic Bacillus species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373000"}
{"pmid": "4373001", "title": "Protein kinase activities during maturation in Xenopus laevis oocytes.", "content": "Protein kinase activities during maturation in Xenopus laevis oocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373001"}
{"pmid": "4373002", "title": "Commentary. Insulin receptors, cell membranes and hormone action.", "content": "Commentary. Insulin receptors, cell membranes and hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373002"}
{"pmid": "4373003", "title": "Effects of methadone on steroid biosynthesis in rat adrenocortical cells.", "content": "Effects of methadone on steroid biosynthesis in rat adrenocortical cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373003"}
{"pmid": "4373004", "title": "Hormone and adenosine 3', 5' cyclic monophosphate stimulated phosphorylation of human erythrocyte membranes.", "content": "Hormone and adenosine 3', 5' cyclic monophosphate stimulated phosphorylation of human erythrocyte membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373004"}
{"pmid": "4373006", "title": "Lack of correlation between cyclic AMP synthesis and free fatty acid release in brown fat of cold-adapted rats.", "content": "Lack of correlation between cyclic AMP synthesis and free fatty acid release in brown fat of cold-adapted rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373006"}
{"pmid": "4373005", "title": "The occurrence of an inhibitor of lipid peroxidation in rat liver soluble fraction and its effect on microsomal drug oxidations.", "content": "The occurrence of an inhibitor of lipid peroxidation in rat liver soluble fraction and its effect on microsomal drug oxidations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373005"}
{"pmid": "4373007", "title": "Papaverine-induced changes in cultured human melanoma cells.", "content": "Papaverine-induced changes in cultured human melanoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373007"}
{"pmid": "4373009", "title": "Acinomycin D and purine transport in cultured rat hepatoma cells.", "content": "Acinomycin D and purine transport in cultured rat hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373009"}
{"pmid": "4373008", "title": "Rabbit testicular capsular contractions--prostaglandins, cyclic adenosine 3',5'-monophosphate and epinephrine.", "content": "Rabbit testicular capsular contractions--prostaglandins, cyclic adenosine 3',5'-monophosphate and epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373008"}
{"pmid": "4373010", "title": "Inhibition by papaverine of cGMP and cAMP phosphodiesterases from the rat heart.", "content": "Inhibition by papaverine of cGMP and cAMP phosphodiesterases from the rat heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373010"}
{"pmid": "4373012", "title": "The role of basic substances of high molecular weight in the generalized Shwartzman reaction (GSR).", "content": "The role of basic substances of high molecular weight in the generalized Shwartzman reaction (GSR).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373012"}
{"pmid": "4373011", "title": "Apomorphine-induced accumulation of cyclic AMP in isolated retinas of the rabbit.", "content": "Apomorphine-induced accumulation of cyclic AMP in isolated retinas of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373011"}
{"pmid": "4373013", "title": "On the absorption, excretion and metabolism of pentaerythritoltetranicotinate.", "content": "On the absorption, excretion and metabolism of pentaerythritoltetranicotinate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373013"}
{"pmid": "4373016", "title": "The effect of glibenclamide on two enzymes important in gluconeogenesis.", "content": "The effect of glibenclamide on two enzymes important in gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373016"}
{"pmid": "4373019", "title": "The pituitary melanotrophic hormones.", "content": "The pituitary melanotrophic hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373019"}
{"pmid": "4373022", "title": "Laryngeal paralysis due to peripheral nerve damage.", "content": "Laryngeal paralysis due to peripheral nerve damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373022"}
{"pmid": "4373023", "title": "Histochemical and biochemical studies in ultraviolet irradiated tissue culture.", "content": "Histochemical and biochemical studies in ultraviolet irradiated tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373023"}
{"pmid": "4373018", "title": "Action of niceritrol (pentaerythritoltetranicotinate) on lipid accumulation in aortas of cholesterol-fed rabbits independent of contemporary reduction of serum lipids.", "content": "Action of niceritrol (pentaerythritoltetranicotinate) on lipid accumulation in aortas of cholesterol-fed rabbits independent of contemporary reduction of serum lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373018"}
{"pmid": "4373025", "title": "Experiments with human papilloma virus in cell culture.", "content": "Experiments with human papilloma virus in cell culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373025"}
{"pmid": "4373024", "title": "Differential effects of propranolol on heart rate and plasma renin activity in patients treated with minoxidil.", "content": "Differential effects of propranolol on heart rate and plasma renin activity in patients treated with minoxidil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373024"}
{"pmid": "4373026", "title": "Cytochemical demonstration of dihydrofolate reductase activity.", "content": "Cytochemical demonstration of dihydrofolate reductase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373026"}
{"pmid": "4373017", "title": "The effect of niceritrol (pentaerythritoltetranicotinate) and clofibrate upon hyperlipemia and atherosclerosis induced in rabbits by cholesterol-free semisynthetic diets.", "content": "The effect of niceritrol (pentaerythritoltetranicotinate) and clofibrate upon hyperlipemia and atherosclerosis induced in rabbits by cholesterol-free semisynthetic diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373017"}
{"pmid": "4373027", "title": "Calcium-binding protein and vitamin D metabolism in experimental protein malnutrition.", "content": "Calcium-binding protein and vitamin D metabolism in experimental protein malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373027"}
{"pmid": "4373028", "title": "A comparative electron spin resonance study of the erythrocyte membrane in myotonic muscular dystrophy.", "content": "A comparative electron spin resonance study of the erythrocyte membrane in myotonic muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373028"}
{"pmid": "4373029", "title": "A predictable modification of enzyme specificity. Selective alteration of DNA bases by metal ions to promote cleavage specificity by deoxyribonuclease.", "content": "A predictable modification of enzyme specificity. Selective alteration of DNA bases by metal ions to promote cleavage specificity by deoxyribonuclease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373029"}
{"pmid": "4373030", "title": "Purification and properties of a neutral protease from rat liver chromatin.", "content": "Purification and properties of a neutral protease from rat liver chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373030"}
{"pmid": "4373031", "title": "The separation, purification, and characterization of ethanolamine kinase and choline kinase from rat liver.", "content": "The separation, purification, and characterization of ethanolamine kinase and choline kinase from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373031"}
{"pmid": "4373032", "title": "Molecular kinetics of beef heart lactate dehydrogenase.", "content": "Molecular kinetics of beef heart lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373032"}
{"pmid": "4373033", "title": "A spin-label study of energy-coupled active transport in Escherichia coli membrane vesicles.", "content": "A spin-label study of energy-coupled active transport in Escherichia coli membrane vesicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373033"}
{"pmid": "4373034", "title": "Purification and characterization of adenosine-adenosine cyclic 3',5'-monophosphate binding protein factors from rabbit erythrocytes.", "content": "Purification and characterization of adenosine-adenosine cyclic 3',5'-monophosphate binding protein factors from rabbit erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373034"}
{"pmid": "4373035", "title": "Thermodynamic relationships between the mitochondrial oxidation-reduction reactions and cellular ATP levels in ascites tumor cells and perfused rat liver.", "content": "Thermodynamic relationships between the mitochondrial oxidation-reduction reactions and cellular ATP levels in ascites tumor cells and perfused rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373035"}
{"pmid": "4373036", "title": "The kinetics of oxidation of reduced cytochrome c by ferricyanide derivatives.", "content": "The kinetics of oxidation of reduced cytochrome c by ferricyanide derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373036"}
{"pmid": "4373037", "title": "Studies on polynucleotides containing hybrid sequences. Synthesis of oligonucleotides possessing a single ribonucleotidyl-(3'-5')-deoxyribonucleotide linkage.", "content": "Studies on polynucleotides containing hybrid sequences. Synthesis of oligonucleotides possessing a single ribonucleotidyl-(3'-5')-deoxyribonucleotide linkage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373037"}
{"pmid": "4373039", "title": "Chloroacetaldehyde-modified dinucleoside phosphates. Dynamic fluorescence quenching and quenching due to intramolecular complexation.", "content": "Chloroacetaldehyde-modified dinucleoside phosphates. Dynamic fluorescence quenching and quenching due to intramolecular complexation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373039"}
{"pmid": "4373038", "title": "Cylic adenosine 3',5'-monophosphate responses to concanavalin A in human lymphocytes. Evidence that the response involves specific carbohydrate receptors on the cell surface.", "content": "Cylic adenosine 3',5'-monophosphate responses to concanavalin A in human lymphocytes. Evidence that the response involves specific carbohydrate receptors on the cell surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373038"}
{"pmid": "4373040", "title": "The mode of interaction of mitomycin C with deoxyribonucleic acid and other polynucleotides in vitro.", "content": "The mode of interaction of mitomycin C with deoxyribonucleic acid and other polynucleotides in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373040"}
{"pmid": "4373041", "title": "Inhibitory effect of complex formation with oligodeoxyribonucleotide ethyl phosphotriesters on transfer ribonucleic acid aminoacylation.", "content": "Inhibitory effect of complex formation with oligodeoxyribonucleotide ethyl phosphotriesters on transfer ribonucleic acid aminoacylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373041"}
{"pmid": "4373042", "title": "Lipid interactions in membranes of extremely halophilic bacteria. I. Electron spin resonance and dilatometric studies of bilayer structure.", "content": "Lipid interactions in membranes of extremely halophilic bacteria. I. Electron spin resonance and dilatometric studies of bilayer structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373042"}
{"pmid": "4373043", "title": "Lipid interactions in membranes of extremely halophilic bacteria. II. Modification of the bilayer structure by squalene.", "content": "Lipid interactions in membranes of extremely halophilic bacteria. II. Modification of the bilayer structure by squalene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373043"}
{"pmid": "4373044", "title": "Studies on motional characteristics and distribution of protonated and anionic forms of spin-labeled 2,4-dinitrophenol in phospholipid bilayer membranes.", "content": "Studies on motional characteristics and distribution of protonated and anionic forms of spin-labeled 2,4-dinitrophenol in phospholipid bilayer membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373044"}
{"pmid": "4373045", "title": "25-Hydroxyvitamin D3-1-hydroxylase. Inhibition in vitro by rat and pig tissues.", "content": "25-Hydroxyvitamin D3-1-hydroxylase. Inhibition in vitro by rat and pig tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373045"}
{"pmid": "4373046", "title": "Interaction of glycyl-L-phenylalanine with Escherichia coli phenylalanyl-tRNA synthetase.", "content": "Interaction of glycyl-L-phenylalanine with Escherichia coli phenylalanyl-tRNA synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373046"}
{"pmid": "4373047", "title": "Inhibition of phosphodiesterases from Bacillus subtilis by nucleoside triphosphates.", "content": "Inhibition of phosphodiesterases from Bacillus subtilis by nucleoside triphosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373047"}
{"pmid": "4373048", "title": "The interaction of thrombin and heparin. Proflavine dye binding studies.", "content": "The interaction of thrombin and heparin. Proflavine dye binding studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373048"}
{"pmid": "4373049", "title": "Biosynthesis of cholestanol: conversion of cholesterol into 4-cholesten-3-one by rat liver microsomes.", "content": "Biosynthesis of cholestanol: conversion of cholesterol into 4-cholesten-3-one by rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373049"}
{"pmid": "4373050", "title": "Formation of polyprenol monophosphate glucose in Shigella flexneri.", "content": "Formation of polyprenol monophosphate glucose in Shigella flexneri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373050"}
{"pmid": "4373051", "title": "Diol lipids. XXVI. Identification of a threo-butane-2,3-diol phospholipid from Actinomyces olivaceus.", "content": "Diol lipids. XXVI. Identification of a threo-butane-2,3-diol phospholipid from Actinomyces olivaceus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373051"}
{"pmid": "4373052", "title": "In vitro incorporation of (3H)serine into phospholipids of proliferating and calcifying epiphyseal cartilage and liver.", "content": "In vitro incorporation of (3H)serine into phospholipids of proliferating and calcifying epiphyseal cartilage and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373052"}
{"pmid": "4373053", "title": "Changes in the phospholipid composition in the differentiating cellular slime mold, Dictyostelium discoideum.", "content": "Changes in the phospholipid composition in the differentiating cellular slime mold, Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373053"}
{"pmid": "4373054", "title": "Interaction by sonication of C-apolipoproteins with lipid: an electron microscopic study.", "content": "Interaction by sonication of C-apolipoproteins with lipid: an electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373054"}
{"pmid": "4373056", "title": "Preparative isoelectric focusing of human serum high-density lipoprotein (HDL3).", "content": "Preparative isoelectric focusing of human serum high-density lipoprotein (HDL3).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373056"}
{"pmid": "4373055", "title": "Lung-toxic furanoterpenoids produced by sweet potatoes (Ipomoea batatas) following microbial infection.", "content": "Lung-toxic furanoterpenoids produced by sweet potatoes (Ipomoea batatas) following microbial infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373055"}
{"pmid": "4373057", "title": "The action of protamine on clearing factor lipase and on plasma triglyceride metabolism.", "content": "The action of protamine on clearing factor lipase and on plasma triglyceride metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373057"}
{"pmid": "4373059", "title": "Biosynthesis of diglyceride from phosphatidic acid in the membranes of Bacillus subtilis.", "content": "Biosynthesis of diglyceride from phosphatidic acid in the membranes of Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373059"}
{"pmid": "4373058", "title": "Composition and synthesis of gangliosides in mammary gland and milk of the bovine.", "content": "Composition and synthesis of gangliosides in mammary gland and milk of the bovine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373058"}
{"pmid": "4373060", "title": "Theoretical analysis of the molecular motion of spin labels in membranes. ESR spectra of labeled Bacillus subtilis membranes.", "content": "Theoretical analysis of the molecular motion of spin labels in membranes. ESR spectra of labeled Bacillus subtilis membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373060"}
{"pmid": "4373061", "title": "Effect of ATP on the intermediary steps of the reaction of the (Na+ plusK+)-dependent enzyme system. III. Effect on the p-nitrophenylphosphatase activity of the system.", "content": "Effect of ATP on the intermediary steps of the reaction of the (Na+ plusK+)-dependent enzyme system. III. Effect on the p-nitrophenylphosphatase activity of the system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373061"}
{"pmid": "4373062", "title": "The photo-oxidation of horse heart cytochrome c and native cytochrome c2 by reaction centres from Rhodopseudomonas spheroides R26.", "content": "The photo-oxidation of horse heart cytochrome c and native cytochrome c2 by reaction centres from Rhodopseudomonas spheroides R26.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373062"}
{"pmid": "4373063", "title": "Flash photolysis-electron spin resonance study of the effect of o-phenanthroline and temperature on the decay time of the ESR signal B1 in reaction-center preparations and chromatophores of mutant and wild strains of Rhodopseudomonas spheroides and Rhodospirillum rubrum.", "content": "Flash photolysis-electron spin resonance study of the effect of o-phenanthroline and temperature on the decay time of the ESR signal B1 in reaction-center preparations and chromatophores of mutant and wild strains of Rhodopseudomonas spheroides and Rhodospirillum rubrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373063"}
{"pmid": "4373064", "title": "A new EPR-detectable component in the ubiquinol-cytochrome c reductase segment of the respiratory chain.", "content": "A new EPR-detectable component in the ubiquinol-cytochrome c reductase segment of the respiratory chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373064"}
{"pmid": "4373066", "title": "Separation of isozymes of horse liver alcohol dehydrogenase and purification of the enzyme by affinity chromatography on an immobilized AMP-analogue.", "content": "Separation of isozymes of horse liver alcohol dehydrogenase and purification of the enzyme by affinity chromatography on an immobilized AMP-analogue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373066"}
{"pmid": "4373065", "title": "Further characterization of a photosystem-II particle isolated from spinach chloroplasts by triton treatment: the reaction-center components.", "content": "Further characterization of a photosystem-II particle isolated from spinach chloroplasts by triton treatment: the reaction-center components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373065"}
{"pmid": "4373068", "title": "An enzyme thermistor.", "content": "An enzyme thermistor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373068"}
{"pmid": "4373067", "title": "Isolation of angiotensin-converting enzyme without kininase activity from hog and guinea pig plasma.", "content": "Isolation of angiotensin-converting enzyme without kininase activity from hog and guinea pig plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373067"}
{"pmid": "4373069", "title": "Conversion of UDP-D-glucuronic acid to UDP-D-apiose and UDP-D-xylose by an enzyme isolated from Lemna minor.", "content": "Conversion of UDP-D-glucuronic acid to UDP-D-apiose and UDP-D-xylose by an enzyme isolated from Lemna minor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373069"}
{"pmid": "4373071", "title": "Pigeon liver diacetyl reductase. Kinetic and thermodynamic studies with NADH as coenzyme.", "content": "Pigeon liver diacetyl reductase. Kinetic and thermodynamic studies with NADH as coenzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373071"}
{"pmid": "4373070", "title": "The nature of modifications by various anions of synthetic and hydrolytic activities of multifunctional glucose-6-phosphatase.", "content": "The nature of modifications by various anions of synthetic and hydrolytic activities of multifunctional glucose-6-phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373070"}
{"pmid": "4373072", "title": "Molecular weight determinations of hydrophilic proteins by cationic detergent electrophoresis. Application to membrane proteins.", "content": "Molecular weight determinations of hydrophilic proteins by cationic detergent electrophoresis. Application to membrane proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373072"}
{"pmid": "4373073", "title": "Non-specific protein binding by adsorbents designed for the specific affinity chromatography of sialidase in crude bacterial extracts.", "content": "Non-specific protein binding by adsorbents designed for the specific affinity chromatography of sialidase in crude bacterial extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373073"}
{"pmid": "4373074", "title": "The intermolecular cross-links in rat uterine collagen.", "content": "The intermolecular cross-links in rat uterine collagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373074"}
{"pmid": "4373076", "title": "Pressure-induced elevation of phase transition temperature in dipalmitoylphosphatidylcholine bilayers. An electron spin resonance measurement of the enthalpy of phase transition.", "content": "Pressure-induced elevation of phase transition temperature in dipalmitoylphosphatidylcholine bilayers. An electron spin resonance measurement of the enthalpy of phase transition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373076"}
{"pmid": "4373075", "title": "Isolation of the Ochromanas danica plasma membrane and identification of several membrane enzymes.", "content": "Isolation of the Ochromanas danica plasma membrane and identification of several membrane enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373075"}
{"pmid": "4373077", "title": "The size of the repeating unit of the repetitive mitochondrial DNA from a \"low-density\" petite mutant of yeast.", "content": "The size of the repeating unit of the repetitive mitochondrial DNA from a \"low-density\" petite mutant of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373077"}
{"pmid": "4373078", "title": "Preparation and properties of poly(5-ethylcytidylic acid), a poly(5-methylcytidylic acid) analogue.", "content": "Preparation and properties of poly(5-ethylcytidylic acid), a poly(5-methylcytidylic acid) analogue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373078"}
{"pmid": "4373079", "title": "Ribonuclease and phosphodiesterase activities in rat hepatocyte plasma membranes.", "content": "Ribonuclease and phosphodiesterase activities in rat hepatocyte plasma membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373079"}
{"pmid": "4373080", "title": "Multiple mechanisms of regulation of purine biosynthesis de novo in intact tumor cells.", "content": "Multiple mechanisms of regulation of purine biosynthesis de novo in intact tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373080"}
{"pmid": "4373081", "title": "Regulation of N-acetylglucosamine kinase synthesis in yeast.", "content": "Regulation of N-acetylglucosamine kinase synthesis in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373081"}
{"pmid": "4373088", "title": "A molecular orbital treatment of Cu(II) proteins.", "content": "A molecular orbital treatment of Cu(II) proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373088"}
{"pmid": "4373091", "title": "Immunological stimulation with modified cancer cells.", "content": "Immunological stimulation with modified cancer cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373091"}
{"pmid": "4373092", "title": "Adrenocortical steroidogenesis and aminoglutethimide (A. G.). II. Cytochemical and ultrastructural changes. Pratical and theoretical values.", "content": "Adrenocortical steroidogenesis and aminoglutethimide (A. G.). II. Cytochemical and ultrastructural changes. Pratical and theoretical values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373092"}
{"pmid": "4373093", "title": "Antiviral effect of asparaginase and of Burkitt cell extracts in combination with other drugs.", "content": "Antiviral effect of asparaginase and of Burkitt cell extracts in combination with other drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373093"}
{"pmid": "4373094", "title": "Fractionation of cigarette smoke condensate prior to bioassays for carcinogenicity.", "content": "Fractionation of cigarette smoke condensate prior to bioassays for carcinogenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373094"}
{"pmid": "4373096", "title": "Developmental patterns of glycerokinase and cytochrome-c-oxidase in the brown adipose tissue of hypotrophic rats.", "content": "Developmental patterns of glycerokinase and cytochrome-c-oxidase in the brown adipose tissue of hypotrophic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373096"}
{"pmid": "4373097", "title": "The effects of ACTH, dexamethasone and HCG on plasma levels of dihydrotestosterone in hirsutism.", "content": "The effects of ACTH, dexamethasone and HCG on plasma levels of dihydrotestosterone in hirsutism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373097"}
{"pmid": "4373098", "title": "Cytoplasmic tubule-containing vacuoles and endoplasmic tubuloreticular inclusions in the lymphocytes of a child with an unidentified form of cerebroretinal degeneration.", "content": "Cytoplasmic tubule-containing vacuoles and endoplasmic tubuloreticular inclusions in the lymphocytes of a child with an unidentified form of cerebroretinal degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373098"}
{"pmid": "4373099", "title": "Effect of polyelectrolytes on the kinetics of ionic reactions. III. Hydrolysis of pyrophosphate in poly-(ethyleneimine) solutions.", "content": "Effect of polyelectrolytes on the kinetics of ionic reactions. III. Hydrolysis of pyrophosphate in poly-(ethyleneimine) solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373099"}
{"pmid": "4373100", "title": "Reagent gases for G.C.-M.S. analyses.", "content": "Reagent gases for G.C.-M.S. analyses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373100"}
{"pmid": "4373101", "title": "Studies on isolation and characterization of ceramide trihexosidase.", "content": "Studies on isolation and characterization of ceramide trihexosidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373101"}
{"pmid": "4373105", "title": "Influence of storage temperature of florisil on analysis of polychlorinated biphenyls.", "content": "Influence of storage temperature of florisil on analysis of polychlorinated biphenyls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373105"}
{"pmid": "4373104", "title": "Toxicity study of two oil spill reagents toward Hudson River fish species.", "content": "Toxicity study of two oil spill reagents toward Hudson River fish species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373104"}
{"pmid": "4373107", "title": "Possible role of dark cells of the collecting tubules in acidification of the urine.", "content": "Possible role of dark cells of the collecting tubules in acidification of the urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373107"}
{"pmid": "4373106", "title": "Biochemical changes induced by ethyl acetate in blood and liver of rat.", "content": "Biochemical changes induced by ethyl acetate in blood and liver of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373106"}
{"pmid": "4373108", "title": "Letter: Camera or scanner for bone scans using 99Tcm pyrophosphate.", "content": "Letter: Camera or scanner for bone scans using 99Tcm pyrophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373108"}
{"pmid": "4373109", "title": "Multiple intraosseous lipomas with type-IV hyperlipoproteinemia. A case report.", "content": "Multiple intraosseous lipomas with type-IV hyperlipoproteinemia. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373109"}
{"pmid": "4373110", "title": "Half-clearance time of 198Au colloid as a discriminant of liver abscess and malignancy.", "content": "Half-clearance time of 198Au colloid as a discriminant of liver abscess and malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373110"}
{"pmid": "4373111", "title": "Odontoma formation in the jaw following irradiation of an adolescent.", "content": "Odontoma formation in the jaw following irradiation of an adolescent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373111"}
{"pmid": "4373112", "title": "Angiographic evaluation of the regression of an extensive juvenile nasopharyngeal angiofibroma after radiation therapy: a case report with therapeutic implications.", "content": "Angiographic evaluation of the regression of an extensive juvenile nasopharyngeal angiofibroma after radiation therapy: a case report with therapeutic implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373112"}
{"pmid": "4373113", "title": "Fibrous histiocytoma of the thumb.", "content": "Fibrous histiocytoma of the thumb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373113"}
{"pmid": "4373114", "title": "Editorial: Late onset of puberty.", "content": "Editorial: Late onset of puberty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373114"}
{"pmid": "4373115", "title": "Letter: Comparison between free thyroxine index and effective thyroxine ratio.", "content": "Letter: Comparison between free thyroxine index and effective thyroxine ratio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373115"}
{"pmid": "4373116", "title": "Plasma tryptophan and sheep.", "content": "Plasma tryptophan and sheep. Free, bound, and total plasma tryptophan (F.P.T., B.P.T., and T.P.T.) levels have been measured throughout the night in six young female volunteers. All-night polygraphic sleep recordings were also made. No direct temporal relationship was found between plasma tryptophan levels and specific sleep stages. The mean F.P.T. levels, however, were found to have a positive correlation with rapid-eye-movement (R.E.M.) sleep and a negative correlation with non-R.E.M. sleep. An inverse relationship existed between the F.P.T. and B.P.T. levels. There appeared to be a diurnal variation in F.P.T. levels, with high readings in the first half of the night.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373116"}
{"pmid": "4373117", "title": "Peripheral neuropathy in acromegaly.", "content": "Peripheral neuropathy in acromegaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373117"}
{"pmid": "4373118", "title": "Pathophysiology in multiple sclerosis.", "content": "Pathophysiology in multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373118"}
{"pmid": "4373120", "title": "The pattern of peripheral nerve regeneration induced by crush in rats with severe acrylamide neuropathy.", "content": "The pattern of peripheral nerve regeneration induced by crush in rats with severe acrylamide neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373120"}
{"pmid": "4373119", "title": "Clinical features of spinal vascular malformations.", "content": "Clinical features of spinal vascular malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373119"}
{"pmid": "4373121", "title": "Tangier disease.", "content": "Tangier disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373121"}
{"pmid": "4373122", "title": "Peripheral nerve changes in amyloid neuropathy.", "content": "Peripheral nerve changes in amyloid neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373122"}
{"pmid": "4373123", "title": "Endoneurial space and its constituents in the sural nerve of patients with neuropathy.", "content": "Endoneurial space and its constituents in the sural nerve of patients with neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373123"}
{"pmid": "4373124", "title": "Morphine and related compounds: evidence that they decrease available neurotransmitter in Aplysia californica.", "content": "Morphine and related compounds: evidence that they decrease available neurotransmitter in Aplysia californica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373124"}
{"pmid": "4373127", "title": "Effects of electrical stimulation on acetylcholine levels in central cholinergic nerve terminals.", "content": "Effects of electrical stimulation on acetylcholine levels in central cholinergic nerve terminals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373127"}
{"pmid": "4373128", "title": "Synaptic connections between medullary inspiratory neurons and phrenic motoneurons as revealed by cross-correlation.", "content": "Synaptic connections between medullary inspiratory neurons and phrenic motoneurons as revealed by cross-correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373128"}
{"pmid": "4373129", "title": "Mesencephalic dopamine neurons projecting to neocortex.", "content": "Mesencephalic dopamine neurons projecting to neocortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373129"}
{"pmid": "4373130", "title": "Histochemical confirmation for dopaminergic innervation of the rat cerebral cortex after destruction of the noradrenergic ascending pathways.", "content": "Histochemical confirmation for dopaminergic innervation of the rat cerebral cortex after destruction of the noradrenergic ascending pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373130"}
{"pmid": "4373132", "title": "Choline uptake in glial cell cultures.", "content": "Choline uptake in glial cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373132"}
{"pmid": "4373131", "title": "(3H)Uridine uptake and incorporation into RNA in the C-6 glial cells following dibutyryl cyclic AMP treatment.", "content": "(3H)Uridine uptake and incorporation into RNA in the C-6 glial cells following dibutyryl cyclic AMP treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373131"}
{"pmid": "4373133", "title": "L-Tryptophan as a selective histochemical marker for serotonergic neurons in single-cell recording studies.", "content": "L-Tryptophan as a selective histochemical marker for serotonergic neurons in single-cell recording studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373133"}
{"pmid": "4373134", "title": "Denervation in the primary olfactory pathway of mice: biochemical and morphological effects.", "content": "Denervation in the primary olfactory pathway of mice: biochemical and morphological effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373134"}
{"pmid": "4373135", "title": "Simultaneous recording of pre- and postsynaptic potentials during the degeneration of the optic tract fiber input to the lateral geniculate nucleus of cats.", "content": "Simultaneous recording of pre- and postsynaptic potentials during the degeneration of the optic tract fiber input to the lateral geniculate nucleus of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373135"}
{"pmid": "4373136", "title": "Reversible suppression of the geniculate PGO waves and of the concomitant increase of excitability of the intrageniculate optic nerve terminals in cats.", "content": "Reversible suppression of the geniculate PGO waves and of the concomitant increase of excitability of the intrageniculate optic nerve terminals in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373136"}
{"pmid": "4373137", "title": "Hypophysectomy, ACTH1-10 and in vitro protein synthesis in rat brain stem slices.", "content": "Hypophysectomy, ACTH1-10 and in vitro protein synthesis in rat brain stem slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373137"}
{"pmid": "4373138", "title": "6-Hydroxydopamine lesions of olfactory tubercles and caudate nuclei: effect on amphetamine-induced stereotyped behavior in rats.", "content": "6-Hydroxydopamine lesions of olfactory tubercles and caudate nuclei: effect on amphetamine-induced stereotyped behavior in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373138"}
{"pmid": "4373139", "title": "Postmortem isolation of synaptosomes from human brain.", "content": "Postmortem isolation of synaptosomes from human brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373139"}
{"pmid": "4373140", "title": "Tectal influences on cat ocular motoneurons.", "content": "Tectal influences on cat ocular motoneurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373140"}
{"pmid": "4373141", "title": "Effects of trans-membrane polarization and TEA injection on monosynaptic actions from motor cortex, red nucleus and group Ia afferents on lumbar motoneurons in the monkey.", "content": "Effects of trans-membrane polarization and TEA injection on monosynaptic actions from motor cortex, red nucleus and group Ia afferents on lumbar motoneurons in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373141"}
{"pmid": "4373142", "title": "Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis.", "content": "Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373142"}
{"pmid": "4373146", "title": "Incorporation of sialic acid into sialidase-treated apolipoprotein of human, very low density lipoprotein by a pork liver sialytransferase.", "content": "Incorporation of sialic acid into sialidase-treated apolipoprotein of human, very low density lipoprotein by a pork liver sialytransferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373146"}
{"pmid": "4373147", "title": "Thermal inactivation of avian liver and muscle fructose 1,6-diphosphatases in the presence of fructose 1,6-diphosphate, AMP, and divalent cations.", "content": "Thermal inactivation of avian liver and muscle fructose 1,6-diphosphatases in the presence of fructose 1,6-diphosphate, AMP, and divalent cations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373147"}
{"pmid": "4373148", "title": "Role of tocopherol in the reduction of mitochondrial NAD.", "content": "Role of tocopherol in the reduction of mitochondrial NAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373148"}
{"pmid": "4373149", "title": "Some characteristics of the exchange of lecithin between rabbit erythrocytes and serum.", "content": "Some characteristics of the exchange of lecithin between rabbit erythrocytes and serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373149"}
{"pmid": "4373150", "title": "Enterovirus neutralizing activity in the gastrointestinal tract of piglets.", "content": "Enterovirus neutralizing activity in the gastrointestinal tract of piglets. Neutralizing activity against porcine enterovirus strain T80 was demonstrated in the contents of the stomach, duodenum or ileum of four piglets which were suckling dams whose milk contained neutralizing substances against the same virus. No neutralizing activity was detected in the gastrointestinal contents of an unsuckled piglet or in four weaned piglets. Extracts of intestinal tissue from each of the above piglets failed to neutralize the virus. Four weaned piglets were dosed orally with live T80 virus. From nine days after infection virus neutralizing activity was found in extracts of tissue prepared from the duodenum, jejunum, ileum, caecum and colon but not in the contents of the gastrointestinal tract and a serological response to the virus was demonstrated. No virus neutralizing activity was detected in gastrointestinal tissue or contents from four weaned piglets inoculated parenterally with live T80 virus or in four piglets dosed orally with inactivated T80 virus and these piglets did not respond serologically to the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373150"}
{"pmid": "4373153", "title": "Sporulation and enterotoxin production by Clostridium perfringens type A under conditions of controlled pH and temperature.", "content": "Sporulation and enterotoxin production by Clostridium perfringens type A under conditions of controlled pH and temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373153"}
{"pmid": "4373152", "title": "Necrotic enteritis in broiler chickens. II. Pathology and proposed pathogenesis.", "content": "Necrotic enteritis in broiler chickens. II. Pathology and proposed pathogenesis. The intestines from 124 dead, sick and normal broiler chickens from 24 cases of necrotic enteritis were subjected to histological examination. Tissue sections from the duodenum, jejunum, ileum and ceca from each broiler were examined histologically for lesions of necrotic enteritis and the presence of coccidia. Lesions of necrotic enteritis were present in one or more areas of the intestine in all but six of 94 dead or sick birds and they were most common and severe in the jejunum. Coccidia were found in only small numbers in both diseased and normal birds. Brown and Brenn stained sections showed Gram-positive bacilli intimately associated with early necrotic lesions on the tips of villi. Tissue sections from the intestines of sick birds permitted a proposed pathogenesis for this disease with the lesion starting at the tips of villi. The similarity in pathogenesis and pathological lesions in this disease of broilers and Clostridium perfringens type C enteritis in baby pigs is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373152"}
{"pmid": "4373151", "title": "Minimal inhibitory concentrations of twenty antimicrobial agents to animal pathogens.", "content": "Minimal inhibitory concentrations of twenty antimicrobial agents to animal pathogens. Minimal inhibitory concentration (M.I.C.) values as determined by an agar-plate-dilution method for 60 bacterial isolates, consisting of Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus of animal origin against 20 antimicrobial drugs are presented. Of all the drugs, gentamicin had the best in vitro antibacterial activity in terms of M.I.C. when considering all the species of organisms together, while spectinomycin had the least activity.An inoculum replicator was a convenient tool in carrying out the agar-plate-dilution method.A comparison of the M.I.C. values of 42 isolates of S. typhimurium with the results obtained by low level method and the Bauer-Kir-by method showed that with few exceptions, there is a general agreement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373151"}
{"pmid": "4373154", "title": "Demonstration in Aspergillus niger of adenyl cyclase, a cyclic adenosine 3',5'-monophosphate-binding protein, and studies on intracellular and extracellular phosphodiesterases.", "content": "Demonstration in Aspergillus niger of adenyl cyclase, a cyclic adenosine 3',5'-monophosphate-binding protein, and studies on intracellular and extracellular phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373154"}
{"pmid": "4373155", "title": "CO2 fixation by the facultative autotroph Thiobacillus novellus during autotrophy-heterotrophy interconversions.", "content": "CO2 fixation by the facultative autotroph Thiobacillus novellus during autotrophy-heterotrophy interconversions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373155"}
{"pmid": "4373157", "title": "Chronic benign congenital myopathy: fingerprint body type.", "content": "Chronic benign congenital myopathy: fingerprint body type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373157"}
{"pmid": "4373156", "title": "Regulation of chloramphenicol synthesis in Streptomyces sp. 3022a. Properties of arylamine synthetase, an enzyme involved in antibiotic biosynthesis.", "content": "Regulation of chloramphenicol synthesis in Streptomyces sp. 3022a. Properties of arylamine synthetase, an enzyme involved in antibiotic biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373156"}
{"pmid": "4373159", "title": "Letter: Klippel-Trenaunay-Weber syndrome.", "content": "Letter: Klippel-Trenaunay-Weber syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373159"}
{"pmid": "4373158", "title": "A review of acrylamide neurotoxicity. Part I. Properties, uses and human exposure.", "content": "A review of acrylamide neurotoxicity. Part I. Properties, uses and human exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373158"}
{"pmid": "4373161", "title": "A field trial to evaluate an intranasal infectious bovine rhinotracheitis vaccine.", "content": "A field trial to evaluate an intranasal infectious bovine rhinotracheitis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373161"}
{"pmid": "4373162", "title": "Metabolic studies of 5-fluorouracil. II. Influence of the route of administration on the dynamics of distribution in man.", "content": "Metabolic studies of 5-fluorouracil. II. Influence of the route of administration on the dynamics of distribution in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373162"}
{"pmid": "4373163", "title": "The prognostic significance of DHS skin tests in patients with carcinoma of bronchus.", "content": "The prognostic significance of DHS skin tests in patients with carcinoma of bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373163"}
{"pmid": "4373164", "title": "Radiation carcinogenesis: an unusual familial occurrence of neoplasia following irradiation in childhood for benign disease.", "content": "Radiation carcinogenesis: an unusual familial occurrence of neoplasia following irradiation in childhood for benign disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373164"}
{"pmid": "4373165", "title": "Reticulum cell sarcoma of the colon following renal transplantation.", "content": "Reticulum cell sarcoma of the colon following renal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373165"}
{"pmid": "4373166", "title": "The management of Wilms' tumor: a comparison of two regimens.", "content": "The management of Wilms' tumor: a comparison of two regimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373166"}
{"pmid": "4373168", "title": "Effect of blockade of angiotensin-I converting enzyme on the blood pressure of renal hypertensive rabbits.", "content": "Effect of blockade of angiotensin-I converting enzyme on the blood pressure of renal hypertensive rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373168"}
{"pmid": "4373170", "title": "Bacterial plasmids.", "content": "Bacterial plasmids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373170"}
{"pmid": "4373171", "title": "Sequences containing methylated nucleotides at the 5' termini of messenger RNAs: possible implications for processing.", "content": "Sequences containing methylated nucleotides at the 5' termini of messenger RNAs: possible implications for processing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373171"}
{"pmid": "4373172", "title": "Increased collagen synthesis in Kirsten sarcoma virus-transformed BALB 3T3 cells grown in the presence of dibutyryl cyclic AMP.", "content": "Increased collagen synthesis in Kirsten sarcoma virus-transformed BALB 3T3 cells grown in the presence of dibutyryl cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373172"}
{"pmid": "4373174", "title": "Accumulation of water during transformation of cells by an avian sarcoma virus.", "content": "Accumulation of water during transformation of cells by an avian sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373174"}
{"pmid": "4373173", "title": "A new mechanism for steroid unresponsiveness: loss of nuclear binding activity of a steroid hormone receptor.", "content": "A new mechanism for steroid unresponsiveness: loss of nuclear binding activity of a steroid hormone receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373173"}
{"pmid": "4373182", "title": "Enhancement by alkylating agents of chemical carcinogen transformation of hamster cells in culture.", "content": "Enhancement by alkylating agents of chemical carcinogen transformation of hamster cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373182"}
{"pmid": "4373183", "title": "A phosphorylation of steroids and a dienone-phenol rearrangement leading to a secosteroidal aldehyde which has a strong toxicity.", "content": "A phosphorylation of steroids and a dienone-phenol rearrangement leading to a secosteroidal aldehyde which has a strong toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373183"}
{"pmid": "4373186", "title": "[Cytosoluble receptor of androgens in a striated skeletal muscle].", "content": "[Cytosoluble receptor of androgens in a striated skeletal muscle].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373186"}
{"pmid": "4373190", "title": "Fasting serum lipoproteins in rural Africans in Rhodesia, measured by membrane filtration and nephelometry.", "content": "Fasting serum lipoproteins in rural Africans in Rhodesia, measured by membrane filtration and nephelometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373190"}
{"pmid": "4373192", "title": "Phospholipid interference and other variables in analysis of non-esterified fatty acids by copper soap formation.", "content": "Phospholipid interference and other variables in analysis of non-esterified fatty acids by copper soap formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373192"}
{"pmid": "4373191", "title": "Serum lipid and lipoprotein levels in normal Chinese.", "content": "Serum lipid and lipoprotein levels in normal Chinese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373191"}
{"pmid": "4373184", "title": "Clinical application of cytochrome A assay of liver specimens for operative indication in critically ill patients with liver failure.", "content": "Clinical application of cytochrome A assay of liver specimens for operative indication in critically ill patients with liver failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373184"}
{"pmid": "4373193", "title": "Young adult osteoporosis.", "content": "Young adult osteoporosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373193"}
{"pmid": "4373194", "title": "Studies on pathogenesis and treatment in postmenopausal and senile osteoporosis.", "content": "Studies on pathogenesis and treatment in postmenopausal and senile osteoporosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373194"}
{"pmid": "4373196", "title": "The physiology of parathyroid hormone.", "content": "The physiology of parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373196"}
{"pmid": "4373195", "title": "Hypocalcaemia and hypoparathyroidism.", "content": "Hypocalcaemia and hypoparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373195"}
{"pmid": "4373197", "title": "Hurler/Scheie genetic compound (mucopolysaccharidosis IH/IS) in Japanese brothers.", "content": "Hurler/Scheie genetic compound (mucopolysaccharidosis IH/IS) in Japanese brothers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373197"}
{"pmid": "4373198", "title": "An extrarenal Wilms' tumor arising from a sacrococcygeal teratoma.", "content": "An extrarenal Wilms' tumor arising from a sacrococcygeal teratoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373198"}
{"pmid": "4373199", "title": "Subcutaneous mastectomy.", "content": "Subcutaneous mastectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373199"}
{"pmid": "4373200", "title": "Proceedings. Urinary cyclic AMP excretion in thyroid disease.", "content": "Proceedings. Urinary cyclic AMP excretion in thyroid disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373200"}
{"pmid": "4373201", "title": "Proceedings: Alterations in liver adenylate cyclase responsiveness during induction of tumours in rat liver with 3'-methyl-4-dimethylaminoazobenzene.", "content": "Proceedings: Alterations in liver adenylate cyclase responsiveness during induction of tumours in rat liver with 3'-methyl-4-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373201"}
{"pmid": "4373202", "title": "The inhibition of renin secretion by alpha-adrenergic stimulation in the isolated rat kidney.", "content": "The inhibition of renin secretion by alpha-adrenergic stimulation in the isolated rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373202"}
{"pmid": "4373203", "title": "The effects of exogenous parathyroid hormone on plasma and urinary adenosine 3', 5'-cyclic monophosphate in man.", "content": "The effects of exogenous parathyroid hormone on plasma and urinary adenosine 3', 5'-cyclic monophosphate in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373203"}
{"pmid": "4373204", "title": "Effects of vertebrate adipokinetic hormones on the rate of in vitro lipid release in insects.", "content": "Effects of vertebrate adipokinetic hormones on the rate of in vitro lipid release in insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373204"}
{"pmid": "4373205", "title": "Hormonal induction of threonine dehydratase in postnatal rat liver.", "content": "Hormonal induction of threonine dehydratase in postnatal rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373205"}
{"pmid": "4373206", "title": "Lack of vitamin D3 synthesis by goldfish (Carassius auratus L.).", "content": "Lack of vitamin D3 synthesis by goldfish (Carassius auratus L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373206"}
{"pmid": "4373207", "title": "Circulating lipids in the golden hamster (Mesocricetus auratus).", "content": "Circulating lipids in the golden hamster (Mesocricetus auratus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373207"}
{"pmid": "4373209", "title": "Liver carabamyl phosphate synthetase in the primitive freshwater bony fishes (Chondrostei, Holostei).", "content": "Liver carabamyl phosphate synthetase in the primitive freshwater bony fishes (Chondrostei, Holostei).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373209"}
{"pmid": "4373208", "title": "Disc electrophoresis of plasma proteins of fish. Physical and chemical characters; localization of fibrinogen, transferrin and ceruloplasmin in the plasma of the rainbow trout (Salmo gairdnerii Richardson).", "content": "Disc electrophoresis of plasma proteins of fish. Physical and chemical characters; localization of fibrinogen, transferrin and ceruloplasmin in the plasma of the rainbow trout (Salmo gairdnerii Richardson).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373208"}
{"pmid": "4373210", "title": "Effect of dibutyryl-cyclic AMP on collagen and non-collagen protein synthesis in cultured human cells.", "content": "Effect of dibutyryl-cyclic AMP on collagen and non-collagen protein synthesis in cultured human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373210"}
{"pmid": "4373211", "title": "Autoradiographic assessment of proteolytic enzyme action using skeletal connective tissue matrices.", "content": "Autoradiographic assessment of proteolytic enzyme action using skeletal connective tissue matrices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373211"}
{"pmid": "4373212", "title": "Biochemical and morphological studies on collagens of horny sponges. Ircinia filaments compared to spongines.", "content": "Biochemical and morphological studies on collagens of horny sponges. Ircinia filaments compared to spongines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373212"}
{"pmid": "4373214", "title": "Induction of liver growth by xenobiotic compounds and other stimuli.", "content": "Induction of liver growth by xenobiotic compounds and other stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373214"}
{"pmid": "4373213", "title": "The collagenase of carrageenin granuloma.", "content": "The collagenase of carrageenin granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373213"}
{"pmid": "4373215", "title": "Experimental aspects of growth plate disorders. A study concerning chondrocytic lysosomes in different physical and metabolic conditions.", "content": "Experimental aspects of growth plate disorders. A study concerning chondrocytic lysosomes in different physical and metabolic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373215"}
{"pmid": "4373218", "title": "Infectious mononucleosis.", "content": "Infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373218"}
{"pmid": "4373225", "title": "Dynamics of insulin release and microtubular-microfilamentous system. VI. Effect of D2O.", "content": "Dynamics of insulin release and microtubular-microfilamentous system. VI. Effect of D2O.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373225"}
{"pmid": "4373226", "title": "Location of feedback receptors: effects of intracranially implanted steroids on plasma LH and LRF response.", "content": "Location of feedback receptors: effects of intracranially implanted steroids on plasma LH and LRF response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373226"}
{"pmid": "4373227", "title": "Synandrogenic and antiandrogenic effect of progestins: comparison with nonprogestational antiandrogens.", "content": "Synandrogenic and antiandrogenic effect of progestins: comparison with nonprogestational antiandrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373227"}
{"pmid": "4373228", "title": "Estrogenic regulation of cytoplasmic receptor populations in estrogen-responsive tissues of the rat.", "content": "Estrogenic regulation of cytoplasmic receptor populations in estrogen-responsive tissues of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373228"}
{"pmid": "4373229", "title": "Actin in pancreatic islet cells.", "content": "Actin in pancreatic islet cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373229"}
{"pmid": "4373230", "title": "Possible role of cyclic AMP and prostaglandin E1 in the dopaminergic control of prolactin release.", "content": "Possible role of cyclic AMP and prostaglandin E1 in the dopaminergic control of prolactin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373230"}
{"pmid": "4373231", "title": "Uterine responsiveness to estrogen in 4-day cycling and in estrogen-primed ovariectomized rats as assessed by uptake and incorporation of (3H) leucine.", "content": "Uterine responsiveness to estrogen in 4-day cycling and in estrogen-primed ovariectomized rats as assessed by uptake and incorporation of (3H) leucine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373231"}
{"pmid": "4373232", "title": "Glucocorticoid-binding macromolecules in the lactating mammary gland of the vole.", "content": "Glucocorticoid-binding macromolecules in the lactating mammary gland of the vole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373232"}
{"pmid": "4373233", "title": "Pituitary-adrenal function in lactating rats.", "content": "Pituitary-adrenal function in lactating rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373233"}
{"pmid": "4373234", "title": "Effects of a single and prolonged ACTH treatment on adrenal, ovarian, uterine and renal blood flow in mice and golden hamsters.", "content": "Effects of a single and prolonged ACTH treatment on adrenal, ovarian, uterine and renal blood flow in mice and golden hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373234"}
{"pmid": "4373236", "title": "Regulatory mechanism of muscle contraction with special reference to the Ca-troponin-tropomyosin system.", "content": "Regulatory mechanism of muscle contraction with special reference to the Ca-troponin-tropomyosin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373236"}
{"pmid": "4373237", "title": "Phenylalanyl-tRNA synthetase from yeast. Steady-state kinetic investigation of the reaction mechanism.", "content": "Phenylalanyl-tRNA synthetase from yeast. Steady-state kinetic investigation of the reaction mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373237"}
{"pmid": "4373238", "title": "Accessible DNA in chromatin.", "content": "Accessible DNA in chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373238"}
{"pmid": "4373239", "title": "Role of manganous ion in the kinetics of pig-heart NAD-specific isocitrate dehydrogenase.", "content": "Role of manganous ion in the kinetics of pig-heart NAD-specific isocitrate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373239"}
{"pmid": "4373240", "title": "Yeast inorganic pyrophosphatase: studies on metal binding.", "content": "Yeast inorganic pyrophosphatase: studies on metal binding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373240"}
{"pmid": "4373241", "title": "Conformational changes in myosin under ATP hydrolysis.", "content": "Conformational changes in myosin under ATP hydrolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373241"}
{"pmid": "4373242", "title": "Proteinase K from Tritirachium album Limber.", "content": "Proteinase K from Tritirachium album Limber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373242"}
{"pmid": "4373244", "title": "Enzymes involved in ketone utilization in different types of muscle: adaptation to exercise.", "content": "Enzymes involved in ketone utilization in different types of muscle: adaptation to exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373244"}
{"pmid": "4373243", "title": "Phosphorylation of vinblastine-isolated microtubules from chick-embryonic muscles.", "content": "Phosphorylation of vinblastine-isolated microtubules from chick-embryonic muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373243"}
{"pmid": "4373245", "title": "The role of acetyl-CoA in the reaction pathway of pig-liver pyruvate carboxylase.", "content": "The role of acetyl-CoA in the reaction pathway of pig-liver pyruvate carboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373245"}
{"pmid": "4373247", "title": "Early biochemical changes in phytohemagglutinin-stimulated peripheral blood lymphocytes from normal and tumor-bearing rats.", "content": "Early biochemical changes in phytohemagglutinin-stimulated peripheral blood lymphocytes from normal and tumor-bearing rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373247"}
{"pmid": "4373246", "title": "Influence of iron deficiency on the cytochromes of Rhodopseudomonas spheroides.", "content": "Influence of iron deficiency on the cytochromes of Rhodopseudomonas spheroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373246"}
{"pmid": "4373248", "title": "A sex-dependent difference in the type of tumours induced by dimethylnitrosamine in the livers of C3Hf mice.", "content": "A sex-dependent difference in the type of tumours induced by dimethylnitrosamine in the livers of C3Hf mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373248"}
{"pmid": "4373249", "title": "Ouabain-induced potentiation on the contractions of the guinea-pig vas deferens.", "content": "Ouabain-induced potentiation on the contractions of the guinea-pig vas deferens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373249"}
{"pmid": "4373250", "title": "The effect of pH on tachyphylaxis to angiotensin peptides in the isolated guinea pig ileum and rat uterus.", "content": "The effect of pH on tachyphylaxis to angiotensin peptides in the isolated guinea pig ileum and rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373250"}
{"pmid": "4373251", "title": "The effect of metronidazole on striated muscle.", "content": "The effect of metronidazole on striated muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373251"}
{"pmid": "4373252", "title": "The role of muscarinic receptors in synaptic transmission and its modulation in the rabbit superior cervical ganglion.", "content": "The role of muscarinic receptors in synaptic transmission and its modulation in the rabbit superior cervical ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373252"}
{"pmid": "4373253", "title": "The effect of prednisolone on the rat phrenic nerve-diaphragm preparation treated with hemicholinium.", "content": "The effect of prednisolone on the rat phrenic nerve-diaphragm preparation treated with hemicholinium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373253"}
{"pmid": "4373254", "title": "Inhibition of oxytocic and hypotensive activities of bradykinin by bradykinin-binding antibodies.", "content": "Inhibition of oxytocic and hypotensive activities of bradykinin by bradykinin-binding antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373254"}
{"pmid": "4373256", "title": "Long-term cell culture of adult rat liver epithelial cells.", "content": "Long-term cell culture of adult rat liver epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373256"}
{"pmid": "4373255", "title": "Virally transformed cells and cytochalasin B. I. The effect of cytochalasin B on cytokinesis, karyokinesis and DNA synthesis in cells.", "content": "Virally transformed cells and cytochalasin B. I. The effect of cytochalasin B on cytokinesis, karyokinesis and DNA synthesis in cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373255"}
{"pmid": "4373258", "title": "Action of organophosphorus compounds on the p-nitrophenyl phosphatase of membranes from rabbit and guinea pig polymorphonuclear leucocytes.", "content": "Action of organophosphorus compounds on the p-nitrophenyl phosphatase of membranes from rabbit and guinea pig polymorphonuclear leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373258"}
{"pmid": "4373257", "title": "The effects of cell population density on the plasma membrane of Acanthamoeba castellanii.", "content": "The effects of cell population density on the plasma membrane of Acanthamoeba castellanii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373257"}
{"pmid": "4373259", "title": "Isolation and characterization of norleucine-resistant baby hamster kidney cells.", "content": "Isolation and characterization of norleucine-resistant baby hamster kidney cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373259"}
{"pmid": "4373260", "title": "Action of organophosphorus compounds on the cation-sensitive p-nitrophenyl phosphatase of membranes from the retinal nerve of the squid.", "content": "Action of organophosphorus compounds on the cation-sensitive p-nitrophenyl phosphatase of membranes from the retinal nerve of the squid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373260"}
{"pmid": "4373261", "title": "Inhibition by x-irradiation and antimetabolites of DNA synthesis without affecting cAMP elevation in isoproterenol-stimulated mouse parotid gland.", "content": "Inhibition by x-irradiation and antimetabolites of DNA synthesis without affecting cAMP elevation in isoproterenol-stimulated mouse parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373261"}
{"pmid": "4373263", "title": "Synthesis of surface glycoproteins and glycosphingolipids in db-cAMP-treated normal and virus-transformed 3T3 cells.", "content": "Synthesis of surface glycoproteins and glycosphingolipids in db-cAMP-treated normal and virus-transformed 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373263"}
{"pmid": "4373262", "title": "Studies on the mechanism of actinomycin D resistance of an SV40-transformed hamster cell line.", "content": "Studies on the mechanism of actinomycin D resistance of an SV40-transformed hamster cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373262"}
{"pmid": "4373264", "title": "Electronic coupling between motoneurones in the abducens nucleus of the cat.", "content": "Electronic coupling between motoneurones in the abducens nucleus of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373264"}
{"pmid": "4373265", "title": "A long propriospinal system with direct effect on motoneurones and on interneurones in the cat lumbosacral cord.", "content": "A long propriospinal system with direct effect on motoneurones and on interneurones in the cat lumbosacral cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373265"}
{"pmid": "4373266", "title": "Inhibitory organization of the thalamic ventrobasal neurons with different peripheral representations.", "content": "Inhibitory organization of the thalamic ventrobasal neurons with different peripheral representations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373266"}
{"pmid": "4373267", "title": "Characteristics of the thalamic ventrobasal relay neurons as a function of conduction velocities of medial lemniscal fibers.", "content": "Characteristics of the thalamic ventrobasal relay neurons as a function of conduction velocities of medial lemniscal fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373267"}
{"pmid": "4373268", "title": "Manganese inhibits adenylate cyclase activity and stimulates phosphodiesterase activity in neuroblastoma cells: its possible implication in manganese-poisoning.", "content": "Manganese inhibits adenylate cyclase activity and stimulates phosphodiesterase activity in neuroblastoma cells: its possible implication in manganese-poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373268"}
{"pmid": "4373269", "title": "Early histochemical changes induced by manganese chloride in the renal tissue of rabbit.", "content": "Early histochemical changes induced by manganese chloride in the renal tissue of rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373269"}
{"pmid": "4373270", "title": "Cell membrane permeability change: an important step in hormone action.", "content": "Cell membrane permeability change: an important step in hormone action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373270"}
{"pmid": "4373271", "title": "Effect of low calcium concentration on the oxidation of NAD-linked substrates in rat liver and tumor mitochondria.", "content": "Effect of low calcium concentration on the oxidation of NAD-linked substrates in rat liver and tumor mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373271"}
{"pmid": "4373272", "title": "Inhibition of Neisseria catarrhalis NE-11 transformation.", "content": "Inhibition of Neisseria catarrhalis NE-11 transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373272"}
{"pmid": "4373273", "title": "Restorative effect of cyclic AMP on the bioelectric processes of calcium deprived ganglia.", "content": "Restorative effect of cyclic AMP on the bioelectric processes of calcium deprived ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373273"}
{"pmid": "4373276", "title": "The effect of neuraminidase on the 5-hydroxytryptamine uptake of human platelets.", "content": "The effect of neuraminidase on the 5-hydroxytryptamine uptake of human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373276"}
{"pmid": "4373275", "title": "Inhibition of spontaneous and induced ovulation in rats by non-steroidal agents.", "content": "Inhibition of spontaneous and induced ovulation in rats by non-steroidal agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373275"}
{"pmid": "4373274", "title": "Oncornavirus released from long-term cultures of human leukemic cells.", "content": "Oncornavirus released from long-term cultures of human leukemic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373274"}
{"pmid": "4373277", "title": "On the modification of the divalent cation-binding by phospholipids in tumours.", "content": "On the modification of the divalent cation-binding by phospholipids in tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373277"}
{"pmid": "4373278", "title": "The effect of theophylline on oxytocin induced contractions in the chronically catheterized pregnant rabbit.", "content": "The effect of theophylline on oxytocin induced contractions in the chronically catheterized pregnant rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373278"}
{"pmid": "4373279", "title": "Ultrastructure of the neurohypophysial glial cells following stalk transection in the rat.", "content": "Ultrastructure of the neurohypophysial glial cells following stalk transection in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373279"}
{"pmid": "4373280", "title": "In vitro and in vivo inhibitory action of 2-amino-4,6-dichloropyrimidine on polio and herpes virus.", "content": "In vitro and in vivo inhibitory action of 2-amino-4,6-dichloropyrimidine on polio and herpes virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373280"}
{"pmid": "4373281", "title": "How well does man thermoregulate during sleep?", "content": "How well does man thermoregulate during sleep?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373281"}
{"pmid": "4373282", "title": "Peripheral neuropathy associated with inhalation of methyl-n-butyl ketone.", "content": "Peripheral neuropathy associated with inhalation of methyl-n-butyl ketone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373282"}
{"pmid": "4373283", "title": "Kininogenase in kidney after ligation of the ureter and after experimental aortic stenosis.", "content": "Kininogenase in kidney after ligation of the ureter and after experimental aortic stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373283"}
{"pmid": "4373285", "title": "Rifampicin and cysteamine protect against the mushroom toxin phalloidin.", "content": "Rifampicin and cysteamine protect against the mushroom toxin phalloidin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373285"}
{"pmid": "4373286", "title": "Unusual cases of facial paralysis.", "content": "Unusual cases of facial paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373286"}
{"pmid": "4373288", "title": "Liver phosphorylase phosphatase: regulation of activity by ATP and Mg ions.", "content": "Liver phosphorylase phosphatase: regulation of activity by ATP and Mg ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373288"}
{"pmid": "4373289", "title": "Dissociation of rabbit muscle cyclic AMP-dependent protein kinase into catalytic and regulatory subunits by p-chloromercuribenzoate and methylmercuric chloride.", "content": "Dissociation of rabbit muscle cyclic AMP-dependent protein kinase into catalytic and regulatory subunits by p-chloromercuribenzoate and methylmercuric chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373289"}
{"pmid": "4373290", "title": "Eukaryotic cytochrome c-like properties of cytochrome c-550 (Thiobacillus novellus).", "content": "Eukaryotic cytochrome c-like properties of cytochrome c-550 (Thiobacillus novellus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373290"}
{"pmid": "4373292", "title": "Absence of binding of thyroid-stimulating hormone subunits to specific sites of thyroid cells.", "content": "Absence of binding of thyroid-stimulating hormone subunits to specific sites of thyroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373292"}
{"pmid": "4373291", "title": "Activities of ribosomal cores deprived of proteins L7, L10, L11 and L12.", "content": "Activities of ribosomal cores deprived of proteins L7, L10, L11 and L12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373291"}
{"pmid": "4373294", "title": "Alkaline phosphatase of Dictyostelium discoideum: cell surface location and colchicine effect on internalization during phagocytosis.", "content": "Alkaline phosphatase of Dictyostelium discoideum: cell surface location and colchicine effect on internalization during phagocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373294"}
{"pmid": "4373293", "title": "The use of a new series of cleavable protein-crosslinkers on the Escherichia coli ribosome.", "content": "The use of a new series of cleavable protein-crosslinkers on the Escherichia coli ribosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373293"}
{"pmid": "4373295", "title": "Requirement for specific carbon sources in the low temperature induction of glycerol kinase in Neurospora crassa.", "content": "Requirement for specific carbon sources in the low temperature induction of glycerol kinase in Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373295"}
{"pmid": "4373296", "title": "Experiments on the effectiveness of inactivatedd infectious bovine rhinotracheitis vaccine.", "content": "Experiments on the effectiveness of inactivatedd infectious bovine rhinotracheitis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373296"}
{"pmid": "4373297", "title": "Immunization of cattle with apolyvalent bovine adenovirus vaccine.", "content": "Immunization of cattle with apolyvalent bovine adenovirus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373297"}
{"pmid": "4373298", "title": "Immunization of cattle with an attenuated IBR vaccine.", "content": "Immunization of cattle with an attenuated IBR vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373298"}
{"pmid": "4373299", "title": "Vaccination of calves against infectious bovine rhinotracheitis using a temperature senstive mutant.", "content": "Vaccination of calves against infectious bovine rhinotracheitis using a temperature senstive mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373299"}
{"pmid": "4373300", "title": "Renin, angiotensin, and norepinephrine in alloxan diabetes.", "content": "Renin, angiotensin, and norepinephrine in alloxan diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373300"}
{"pmid": "4373302", "title": "Estimation of specific antibody to type 2 Herpes simplex virus among patients with carcinoma of the uterine cervix.", "content": "Estimation of specific antibody to type 2 Herpes simplex virus among patients with carcinoma of the uterine cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373302"}
{"pmid": "4373303", "title": "Combined effect of nitrogen mustard and DNA repair inhibitor on the resistant tumor.", "content": "Combined effect of nitrogen mustard and DNA repair inhibitor on the resistant tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373303"}
{"pmid": "4373306", "title": "Cytogenetic and complementation analyses of recessive lethal mutations induced in the X chromosome of Drosophila by three alkylating agents.", "content": "Cytogenetic and complementation analyses of recessive lethal mutations induced in the X chromosome of Drosophila by three alkylating agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373306"}
{"pmid": "4373307", "title": "The role of latent viruses in subline differentiation in inbred strains of mice.", "content": "The role of latent viruses in subline differentiation in inbred strains of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373307"}
{"pmid": "4373314", "title": "Plasma androstenedione (A) and dihydrotesto-terone (DHT) in patients with trophoblastic disease and the effect of chemotherapy and oophorectomy.", "content": "Plasma androstenedione (A) and dihydrotesto-terone (DHT) in patients with trophoblastic disease and the effect of chemotherapy and oophorectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373314"}
{"pmid": "4373322", "title": "Renal angiomyolipoma versus renal carcinoma. Is an angiographic differential diagnosis possible?", "content": "Renal angiomyolipoma versus renal carcinoma. Is an angiographic differential diagnosis possible?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373322"}
{"pmid": "4373359", "title": "Dream recall and the menstrual cycle.", "content": "Dream recall and the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373359"}
{"pmid": "4373367", "title": "Hormone-mediated dimerization of microsomal estradiol receptor.", "content": "Hormone-mediated dimerization of microsomal estradiol receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373367"}
{"pmid": "4373368", "title": "Conformational differences in Myosin, II. Evidence for differences in the conformation induced by bound or hydrolyzed adenosine triphosphate.", "content": "Conformational differences in Myosin, II. Evidence for differences in the conformation induced by bound or hydrolyzed adenosine triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373368"}
{"pmid": "4373361", "title": "Single-copy nuclear DNA in the cytoplasm of undifferentiated embryo cells and tumor cells of man, chick and hamster.", "content": "Single-copy nuclear DNA in the cytoplasm of undifferentiated embryo cells and tumor cells of man, chick and hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373361"}
{"pmid": "4373369", "title": "Influence of noradrenalin, prostaglandin E1 and inhibitors of phosphodiesterase activity on levels of the cyclic adenosine 3':5'-monophosphate in somatic cell hybrids.", "content": "Influence of noradrenalin, prostaglandin E1 and inhibitors of phosphodiesterase activity on levels of the cyclic adenosine 3':5'-monophosphate in somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373369"}
{"pmid": "4373370", "title": "Specific estrogen binding sites on the liver chromatin of estrogen-pretreated roosters.", "content": "Specific estrogen binding sites on the liver chromatin of estrogen-pretreated roosters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373370"}
{"pmid": "4373371", "title": "Biosynthesis of sphingomyelin. Transfer of phosphorylcholine from phosphatidylcholine to erythro-ceramide in a cell-free system.", "content": "Biosynthesis of sphingomyelin. Transfer of phosphorylcholine from phosphatidylcholine to erythro-ceramide in a cell-free system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373371"}
{"pmid": "4373372", "title": "Isolation and characterization of nuclear membranes from calf and rat thymus.", "content": "Isolation and characterization of nuclear membranes from calf and rat thymus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373372"}
{"pmid": "4373364", "title": "Aminopeptidase K from Tritirachium album Limber. I. Isolation and some properties.", "content": "Aminopeptidase K from Tritirachium album Limber. I. Isolation and some properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373364"}
{"pmid": "4373373", "title": "Composition of mitochondrial lipids from rat adrenal glands.", "content": "Composition of mitochondrial lipids from rat adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373373"}
{"pmid": "4373374", "title": "The metabolism of sphingosine bases in Tetrahymena pyriformis. Sphingosine kinase and sphingosine-1-phosphate lyase.", "content": "The metabolism of sphingosine bases in Tetrahymena pyriformis. Sphingosine kinase and sphingosine-1-phosphate lyase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373374"}
{"pmid": "4373375", "title": "On the mechanism of gluconeogenesis and its regulation. VIII. Differentiation of regulatory attacks of glucocorticoids, L-lysine and cyclic AMP in renal gluconeogenesis.", "content": "On the mechanism of gluconeogenesis and its regulation. VIII. Differentiation of regulatory attacks of glucocorticoids, L-lysine and cyclic AMP in renal gluconeogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373375"}
{"pmid": "4373362", "title": "Preparation of pure choline and ethanolamine plasmalogens with the use of purified lipase from porcine pancreas.", "content": "Preparation of pure choline and ethanolamine plasmalogens with the use of purified lipase from porcine pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373362"}
{"pmid": "4373376", "title": "Studies on the biosynthesis of cyclitols, XXX. Purification of myo-inositol-1-phosphate synthase of rat testes to homogeneity by affinity chromatography on NAD-sepharose.", "content": "Studies on the biosynthesis of cyclitols, XXX. Purification of myo-inositol-1-phosphate synthase of rat testes to homogeneity by affinity chromatography on NAD-sepharose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373376"}
{"pmid": "4373366", "title": "Synthesis of labelled phosphatidyl-N,N-dimethylethanolamine and phosphatidylcholine.", "content": "Synthesis of labelled phosphatidyl-N,N-dimethylethanolamine and phosphatidylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373366"}
{"pmid": "4373363", "title": "Properties and specificities of sphingosine kinase from blood platelets.", "content": "Properties and specificities of sphingosine kinase from blood platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373363"}
{"pmid": "4373378", "title": "Evidence for a hexosediphosphatase from the cytoplasm of spinach leaves.", "content": "Evidence for a hexosediphosphatase from the cytoplasm of spinach leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373378"}
{"pmid": "4373377", "title": "A possible role of the glycerol phosphate cycle in cyclic AMP-stimulated gluconeogenesis from lactate in perfused rat livers.", "content": "A possible role of the glycerol phosphate cycle in cyclic AMP-stimulated gluconeogenesis from lactate in perfused rat livers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373377"}
{"pmid": "4373380", "title": "Adenylate cyclase from Trypanosoma gambiense.", "content": "Adenylate cyclase from Trypanosoma gambiense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373380"}
{"pmid": "4373381", "title": "Purification and properties of a soluble cyclic AMP-dependent protein kinase from human platelets.", "content": "Purification and properties of a soluble cyclic AMP-dependent protein kinase from human platelets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373381"}
{"pmid": "4373382", "title": "The relation between the blood-level of a substrate and enzyme kinetics studied with glycerol in the rat.", "content": "The relation between the blood-level of a substrate and enzyme kinetics studied with glycerol in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373382"}
{"pmid": "4373383", "title": "Inhibition of the tetrahydrofolic acid cycle in HeLa and LDR cells by parainfluenza virus 1 (Sendai).", "content": "Inhibition of the tetrahydrofolic acid cycle in HeLa and LDR cells by parainfluenza virus 1 (Sendai).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373383"}
{"pmid": "4373384", "title": "The polymorphisms of red cell acid phosphatase, phosphoglucomutase, adenosine deaminase, and adenylate kinase in twins.", "content": "The polymorphisms of red cell acid phosphatase, phosphoglucomutase, adenosine deaminase, and adenylate kinase in twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373384"}
{"pmid": "4373386", "title": "Studies on enzymes of renal gluconeogenesis in alcohol-fed rats.", "content": "Studies on enzymes of renal gluconeogenesis in alcohol-fed rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373386"}
{"pmid": "4373385", "title": "Genetic markers and anthropometry in the populations of the Egyptian oases of El-Kharga and El-Dakhla.", "content": "Genetic markers and anthropometry in the populations of the Egyptian oases of El-Kharga and El-Dakhla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373385"}
{"pmid": "4373387", "title": "An ultrastructural study of adenoid cystic carcinoma of the human salivary gland.", "content": "An ultrastructural study of adenoid cystic carcinoma of the human salivary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373387"}
{"pmid": "4373388", "title": "The effect of bacterial adjuvants on allograft survival after anti-lymphocyte serum (ALS) and donor bone marrow in mice.", "content": "The effect of bacterial adjuvants on allograft survival after anti-lymphocyte serum (ALS) and donor bone marrow in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373388"}
{"pmid": "4373389", "title": "Antibody response in rabbits after smallpox vaccination with varying tissue injury.", "content": "Antibody response in rabbits after smallpox vaccination with varying tissue injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373389"}
{"pmid": "4373390", "title": "Changes in the level of hydrolytic enzymes in the caecum and intestine of rats infected with a virulent strain of Entamoeba histolytica intracaecally.", "content": "Changes in the level of hydrolytic enzymes in the caecum and intestine of rats infected with a virulent strain of Entamoeba histolytica intracaecally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373390"}
{"pmid": "4373391", "title": "Experimental renal hypertension in rhesus monkeys: effect of surgical removal of ischaemic kidney on various parameters.", "content": "Experimental renal hypertension in rhesus monkeys: effect of surgical removal of ischaemic kidney on various parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373391"}
{"pmid": "4373392", "title": "Hyper beta lipoproteinemia (familial hypercholesterolemia). A case report.", "content": "Hyper beta lipoproteinemia (familial hypercholesterolemia). A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373392"}
{"pmid": "4373393", "title": "Antiviral activity of an ether-extracted nonviable preparation of Brucella abortus.", "content": "Antiviral activity of an ether-extracted nonviable preparation of Brucella abortus. Extraction of living Brucella abortus (strain 456) with aqueous ether yielded a nonviable, insoluble residue (Bru-Pel). When injected into mice, Bru-Pel was an effective, nontoxic interferon stimulus. Mice pretreated with Bru-Pel were protected against challenge with otherwise lethal doses of Semliki Forest virus. Significant protection was afforded when Bru-Pel was given as many as 7 days before virus challenge. Evidence is presented dealing with the complex nature of Bru-Pel and with the possibility that the antiviral activity of Bru-Pel may be associated not only with the production of interferon, but with a general increase in the level of nonspecific resistance in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373393"}
{"pmid": "4373394", "title": "Resistance of female mice to vaginal infection induced by Herpesvirus hominis type 2: effects of immunization with Mycobacterium bovis, intravenous injection of specific Herpesvirus hominis type 2 antiserum, and a combination of these procedures.", "content": "Resistance of female mice to vaginal infection induced by Herpesvirus hominis type 2: effects of immunization with Mycobacterium bovis, intravenous injection of specific Herpesvirus hominis type 2 antiserum, and a combination of these procedures. The susceptibility of 4- to 6-week-old female white Swiss mice to intravaginal inoculation with Herpesvirus hominis type 2 (HVH2) and the effect of prior intravenous immunization with Mycobacterium bovis (BCG) and/or treatment with specific HVH2 antiserum (SAS) were investigated. Mice inoculated intravaginally developed vaginitis, posterior paralysis, encephalitis, and death. Prior immunization with BCG either had no effect or appeared in some cases to enhance the course of the disease, whereas a single 0.5-ml intravenous injection of SAS provided significant protection. However, synergistic interaction of BCG immunization and treatment with SAS produced the greatest degree of protection in mice challenged intravaginally with HVH2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373394"}
{"pmid": "4373395", "title": "Induction of interferon in mice by mycoplasmas.", "content": "Induction of interferon in mice by mycoplasmas. Interferon was induced in mice after intraperitoneal inoculation with four different mycoplasmas. Peak levels of between 100 and 300 U of interferon per ml were attained by 6 h postinfection with each of the mycoplasmas except Mycoplasma arthritidis, which induced higher titers (400 to 11,800 U/ml) by this time. A fifth mycoplasma, M. pulmonis, induced interferon inconsistently and at a later (72 to 96 h) time. Mycoplasmatales virus MVL51 and sterile mycoplasmal broth did not stimulate interferon production in vivo. All of the mycoplasmas and MVL51 failed to induce interferon in murine spleen cell, peritoneal exudate cell, or peripheral blood leukocyte cultures. Preinfecting the mycoplasmas with MVL51 or treating the organisms with trypsin or dilutions of specific antisera did not enhance their ability to induce interferon in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373395"}
{"pmid": "4373397", "title": "Agglutination of trypsinized sheep erythrocytes by the pili of Corynebacterium renale.", "content": "Agglutination of trypsinized sheep erythrocytes by the pili of Corynebacterium renale. Corynebacterium renale strains which possessed numerous pili agglutinated trypsinized sheep erythrocytes, whereas those possessing only a few pili did not show such activity. By electron microscopy, the pili of C. renale adhered to the ghost of trypsinized sheep erythrocytes. After the treatment of C. renale with the homologous anti-pili serum, neither the agglutination of trypsinized sheep erythrocytes nor the adherence to the ghost by the pili were found. The adhesive property of the pili of C. renale was thus demonstrated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373397"}
{"pmid": "4373396", "title": "Hyporeactivity due to infection: recognition of a transferable hyporeactive factor in the serum of encephalomyocarditis virus-infected mice.", "content": "Hyporeactivity due to infection: recognition of a transferable hyporeactive factor in the serum of encephalomyocarditis virus-infected mice. As previously reported, mice infected with encephalomyocarditis (EMC) virus progressively develop a state of hyporeactivity to interferon induction as evidenced by an 80% reduction in serum interferon levels produced in response to four different inducers administered 96 h after initiation of infection. In the current report, this hyporesponsiveness was further documented in vitro in peritoneal exudate cells harvested at the time of maximal hyporeactivity (96 h) during EMC virus infection. These peritoneal cell preparations (containing no detectable interferon or virus) produced significantly less interferon than cells from uninfected mice following exposure to Newcastle disease virus or Chikungunya virus. More importantly, hyporeactivity could be transferred to normal peritoneal cells incubated in serum (containing no detectable interferon or virus) from EMC virus-infected mice during the hyporeactive period. Incubation of peritoneal exudate cells with up to a 1:200 dilution of serum from hyporeactive animals still resulted in a significant reduction in the interferon response induced by Newcastle disease virus or Chikungunya virus. Furthermore, it could be shown that this serum hyporeactive factor was effective in mouse cells but not in rabbit, chicken, or human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373396"}
{"pmid": "4373398", "title": "Inability to detect hepatitis B virus or specific antigens in transformed chimpanzee lymphocytes.", "content": "Inability to detect hepatitis B virus or specific antigens in transformed chimpanzee lymphocytes. Transformed chimpanzee lymphocytes were examined to determine whether they would support the replication of hepatitis B virus. After 5 months, no hepatitis B virus, hepatitis B surface antigen, or antibody to hepatitis B surface antigen was detected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373398"}
{"pmid": "4373399", "title": "In vitro tritium labeling of anti-sendai virus antibody.", "content": "In vitro tritium labeling of anti-sendai virus antibody. Anti-Sendai virus immunoglobulin G was tritium labeled in vitro by the borohydride exchange method. Tritium was incorporated into the antibody at 28.5 muCi per mg of protein, with little detectable loss of antiviral activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373399"}
{"pmid": "4373401", "title": "A decade of dreams: a review.", "content": "A decade of dreams: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373401"}
{"pmid": "4373400", "title": "The accurate measurement of vanadium in airborne particulates.", "content": "The accurate measurement of vanadium in airborne particulates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373400"}
{"pmid": "4373403", "title": "Radiation damage in L-histidine-HCl monohydrate.", "content": "Radiation damage in L-histidine-HCl monohydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373403"}
{"pmid": "4373402", "title": "Enhancement of the radioprotective effects of 2-mercaptoethylamine on colony-forming cells by agents which alter cyclic nucleotide levels.", "content": "Enhancement of the radioprotective effects of 2-mercaptoethylamine on colony-forming cells by agents which alter cyclic nucleotide levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373402"}
{"pmid": "4373404", "title": "Toxicity to rabbit retina of \"epithermal\" neutron beam.", "content": "Toxicity to rabbit retina of \"epithermal\" neutron beam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373404"}
{"pmid": "4373405", "title": "The effect of lithium carbonate on the sleep of depressed patients.", "content": "The effect of lithium carbonate on the sleep of depressed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373405"}
{"pmid": "4373406", "title": "Androgen receptors in the nonhistone protein fractions of prostatic chromatin.", "content": "Androgen receptors in the nonhistone protein fractions of prostatic chromatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373406"}
{"pmid": "4373407", "title": "Papovaviridae.", "content": "Papovaviridae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373407"}
{"pmid": "4373408", "title": "Comparison of the capsid polypeptides of various bluetongue virus serotypes.", "content": "Comparison of the capsid polypeptides of various bluetongue virus serotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373408"}
{"pmid": "4373410", "title": "Inhibition of gross murine leukemia virus replication by rifamycin SV and certain of its derivatives in vitro.", "content": "Inhibition of gross murine leukemia virus replication by rifamycin SV and certain of its derivatives in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373410"}
{"pmid": "4373409", "title": "Antiviral antibiotics: inhibition of focus-formation in human or mouse cell cultures by sarcoma-inducing oncornaviruses with rifamycins.", "content": "Antiviral antibiotics: inhibition of focus-formation in human or mouse cell cultures by sarcoma-inducing oncornaviruses with rifamycins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373409"}
{"pmid": "4373411", "title": "Complexity of immunoreactive forms of peptide hormones in plasma and in tissue extracts.", "content": "Complexity of immunoreactive forms of peptide hormones in plasma and in tissue extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373411"}
{"pmid": "4373412", "title": "Heterogeneity of circulating insulin and proinsulin in man.", "content": "Heterogeneity of circulating insulin and proinsulin in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373412"}
{"pmid": "4373413", "title": "Plasma proinsulin-like components.", "content": "Plasma proinsulin-like components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373413"}
{"pmid": "4373414", "title": "Common mechanism of action of somatomedin and insulin on fat cells. Further evidence.", "content": "Common mechanism of action of somatomedin and insulin on fat cells. Further evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373414"}
{"pmid": "4373415", "title": "Characterization of preparations of radioiodinated human chorionic gonadotropin.", "content": "Characterization of preparations of radioiodinated human chorionic gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373415"}
{"pmid": "4373416", "title": "Neurohypophyseal hormones as precursors of hypophysiotropic hormones.", "content": "Neurohypophyseal hormones as precursors of hypophysiotropic hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373416"}
{"pmid": "4373417", "title": "Polypeptide hormone-receptor interactions. A new approach to the study of pancreatic and gut glucagons.", "content": "Polypeptide hormone-receptor interactions. A new approach to the study of pancreatic and gut glucagons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373417"}
{"pmid": "4373420", "title": "Evaluation of anti-tumor effect of corticosteroid on human glioma in vitro.", "content": "Evaluation of anti-tumor effect of corticosteroid on human glioma in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373420"}
{"pmid": "4373419", "title": "Observations on the maturational appearance of the reproductive organs of male infants after treatment with ACTH and corticosteroids.", "content": "Observations on the maturational appearance of the reproductive organs of male infants after treatment with ACTH and corticosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373419"}
{"pmid": "4373421", "title": "Histochemical demonstration of changes in liver cell enzymes in pregnant mice infected with Coxsackie B3 virus.", "content": "Histochemical demonstration of changes in liver cell enzymes in pregnant mice infected with Coxsackie B3 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373421"}
{"pmid": "4373422", "title": "Intense phosphatase activity in the developing rete testis of the newborn rat.", "content": "Intense phosphatase activity in the developing rete testis of the newborn rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373422"}
{"pmid": "4373423", "title": "Vaccination for reproductive efficiency in cattle.", "content": "Vaccination for reproductive efficiency in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373423"}
{"pmid": "4373425", "title": "Acidolin: an antibiotic produced by Lactobacillus acidophilus.", "content": "Acidolin: an antibiotic produced by Lactobacillus acidophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373425"}
{"pmid": "4373424", "title": "Causes and control of swine stillbirths.", "content": "Causes and control of swine stillbirths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373424"}
{"pmid": "4373426", "title": "A new medium for the detection and enumeration of Clostridium perfringens in foods.", "content": "A new medium for the detection and enumeration of Clostridium perfringens in foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373426"}
{"pmid": "4373427", "title": "Histamine releasers and hypoxic vasoconstriction in isolated cat lungs.", "content": "Histamine releasers and hypoxic vasoconstriction in isolated cat lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373427"}
{"pmid": "4373428", "title": "Adrenal adaptation to chronic exercise.", "content": "Adrenal adaptation to chronic exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373428"}
{"pmid": "4373429", "title": "Central neural respiratory stimulatory effect of active respiration.", "content": "Central neural respiratory stimulatory effect of active respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373429"}
{"pmid": "4373431", "title": "Periodic breathing during sleep.", "content": "Periodic breathing during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373431"}
{"pmid": "4373430", "title": "Eccrine sweat gland in Macaca mulatta: physiology, histochemistry, and distribution.", "content": "Eccrine sweat gland in Macaca mulatta: physiology, histochemistry, and distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373430"}
{"pmid": "4373432", "title": "Primary carcinoma liver (a clinico pathological study of 185 cases with liver biopsies).", "content": "Primary carcinoma liver (a clinico pathological study of 185 cases with liver biopsies).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373432"}
{"pmid": "4373433", "title": "Cellular location of degradative enzymes in Staphylococcus aureus.", "content": "Cellular location of degradative enzymes in Staphylococcus aureus. Staphylococus aureus, ATCC 6538P, was fractionated into protoplast membranes, mesosomal vesicles, periplasm, and cytoplasm. These fractions and the culture fluid were then assayed for various degradative enzyme activities. They were not restricted to a single fraction nor dispersed homogeneously, but were distributed predominantly (on the basis of specific activity) as follows: nuclease in the culture fluid; alkaline phosphatase, 5'-nucleotidase, and acid phosphatase in the periplasm; adenosine triphosphatase in the protoplast membrane; and protease (low levels) in mesosomal vesicles. No significant esterase nor cell wall hydrolytic activity was found in any fraction. S. aureus 80/81 was studied for penicillinase activity after induction with benzyl penicillin; this enzyme was localized in the mesosomal vesicles. Electron microscopy did not reveal any ultrastructural changes associated with secretion of the extracellular fraction. Overall, these studies demonstrate that degradative enzymes are located in several surface compartments and that, therefore, the mesosome does not function as a prototype lysosome in S. aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373433"}
{"pmid": "4373434", "title": "Regulation of serine transhydroxymethylase activity in Salmonella typhimurium.", "content": "Regulation of serine transhydroxymethylase activity in Salmonella typhimurium. The regulation of serine transhydroxymethylase (EC 2.1.2.1.; l-serine:tetrahydrofolic-5,10-hydroxymethyltransferase) has been investigated in Salmonella typhimurium LT2. Our results indicate that limitation of a methionine auxotroph for methionine does not cause derepression of this enzyme as reported for Escherichia coli. However, a sixfold decrease in specific activity was observed when S. typhimurium cells were grown in glucose minimal medium supplemented with serine, glycine, methionine, adenine, guanine, and thymine. None of these compounds added to the growth medium individually produced more than a 42% reduction of wild-type enzyme activity. This enhanced repression by the combination of compounds suggests a form of cumulative repression of this enzyme. Growth of serine and thymine auxotrophs, with the respective requirement of each limiting, did not result in increased enzyme activity. However, growth of a purine auxotroph with a limiting amount of either guanine or inosine resulted in a five- to sevenfold increase in enzyme activity. A second condition causing significant derepression (fourfold increase) above the levels observed with cells grown in minimal medium was the addition of 0.5 mug of trimethoprim per ml, an inhibitor of the dihydrofolate reductase activity. (A partial report on this work was presented at 1974 meeting of the American Society for Microbiology.)", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373434"}
{"pmid": "4373435", "title": "Mutants of Salmonella typhimurium defective in transport of branched-chain amino acids.", "content": "Mutants of Salmonella typhimurium defective in transport of branched-chain amino acids. Five mutants, CD15, CD31, CE4, CE5, and CE14, defective in the transport of branched-chain amino acids were isolated as glycyl-l-isoleucine and glycyl-l-valine requirers from an isoleucine-valine-requiring mutant, KA931, of Salmonella typhimurium LT2. Although these transport mutants do not grow in minimal medium supplemented with isoleucine (10 mug/ml) and valine (20 mug/ml), where the parent strain, KA931, grows normally, they do when the supplements are increased 10-fold in concentration, and the growth rate becomes comparable to that of the parent strain. When the apparent K(m) and V(max) for uptake of isoleucine, valine, and leucine in the transport mutants were compared to those of KA931, the K(m) was generally lower in the mutants, and the V(max) for isoleucine and leucine decreased to one-fourth to one-seventh and for valine one-eighth to one-fifteenth of that in the parent. In all mutants except CE5, the transport of methionine, arginine, threonine, and glycine was normal. The transport of threonine in CE5 appeared to be slightly impaired. In addition to the original mutation in the ilvC locus, the transport mutant has a mutation at the ilvT locus, which is closely linked to proC and may be located on the side of proC proximal to purE. About 26-fold difference in values of the co-transduction is noted in reciprocal transductions between KA502 and CD15 strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373435"}
{"pmid": "4373436", "title": "Properties of two homologous alkaline proteases from Streptomyces rectus.", "content": "Properties of two homologous alkaline proteases from Streptomyces rectus. Some physicochemical properties of two thermostable proteases from Streptomyces rectus are described. The enzymes were judged to be identical with respect to molecular weight, inactivation with serine protease inhibitors, and in primary structure by peptide analysis. Amino acid analysis indicated the enzymes had identical compositions except for their amide content. The molecular weights of the enzymes were judged to be 28,000 by sedimentation equilibrium, 26,200 by sedimentation diffusion, and 29,100 from amino acid analysis. Titration of the proteases with diisopropylfluorophosphate and phenylmethane sulfonylfuoride indicate equivalent weights of 28,500 and 32,800 g, respectively, for the proteins. The pentapeptide around the serine residue reacting with diisopropylfluorophosphate was isolated and had the composition: Asx(1), Gly(1), Thr(1), Ser(1), Met(1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373436"}
{"pmid": "4373437", "title": "Rhythms of enzyme activity associated with circadian conidiation in Neurospora crassa.", "content": "Rhythms of enzyme activity associated with circadian conidiation in Neurospora crassa. The mycelial growth front of the band strain of Neurospora grown on a solid surface exhibits a circadian rhythm of conidiation. Enzyme assays on extracts from that mycelium have shown that the activities of 6 of 13 enzymes (nicotinamide adenine dinucleotide nucleosidase, isocitrate lyase, citrate synthase, glyceraldehydephosphate dehydrogenase, phosphogluconate dehydrogenase, and glucose-6-phosphate dehydrogenase) and soluble-protein content oscillate with the visible morphological change. The rhythmic enzymes associated with the Krebs and glyoxylate cycles are more active during conidiogenesis, whereas the activities of the rhythmic enzymes of glycolysis and the hexose monophosphate shunt are reduced during that phase. The absence of enzyme oscillations in wild-type and fluffy strains which do not form conidia under the conditions employed suggests that the enzyme fluctuations are associated with conidiogenesis itself. Oscillations of enzyme activity as a function of time are restricted to the growth front. A permanent record of rhythmicity associated with conidial and nonconidial regions does, however, exist in the mycelial mat behind the growth front. The activities of three enzymes (nicotinamide adenine dinucleotide nucleosidase, glucose-6-phosphate dehydrogenase, and phosphogluconate dehydrogenase) are not directly influenced by CO(2) concentration, but are correlated with the prescence or absence of conidiation which is controlled by CO(2) concentration. In contrast, citrate synthase and malate dehydrogenase activities are correlated with changes in CO(2) concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373437"}
{"pmid": "4373438", "title": "Characterization of Escherichia coli flagellar mutants that are insensitive to catabolite repression.", "content": "Characterization of Escherichia coli flagellar mutants that are insensitive to catabolite repression. In Escherichia coli, the synthesis of the flagellar organelle is sensitive to catabolite repression. Synthesis requires the presence of the cyclic adenosine monophosphate receptor protein (Crp) and 3',5'-cyclic adenosine monophosphate (cAMP); i.e., mutants that lack Crp or adenylcyclase (Cya) synthesize no flagella. We isolated and characterized a series of mutants (cfs) that restored flagella-forming ability in a Crp strain of E. coli. The mutations in these strains were transferred onto episomes and they were then introduced into a variety of other strains. The presence of the mutation resulted in flagella synthesis in Cya and Crp strains as well as in the wild type grown under conditions of catabolite repression. Deletion analysis and other genetic studies indicated that: (i) the cfs mutations had a dominant effect when they were in the transconfiguration in merodiploids: (ii) they occurred in or very close to the flaI gene: and (iii) their expression required the presence of an intact flaI gene adjacent to the cfs mutation. Biochemical studies showed that the synthesis of at least two flagellar polypeptides, the hook subunit and an amber fragment of flagellin, were absent in strains that carried a cya mutation. Their synthesis was depressed in strains grown under conditions of catabolite repression. The presence of the cfs mutation restored the specific synthesis of these two polypeptides. We suggest that the formation of the flaI gene product is the step in flagellar synthesis that is catabolite sensitive and requires cAMP. We propose a regulatory function for the product of the flaI gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373438"}
{"pmid": "4373440", "title": "Fractionation of two diguanylic acids with different internucleotide linkages and its application for analyses of the synthetic products of ribonuclease T1 and spontaneous reaction.", "content": "Fractionation of two diguanylic acids with different internucleotide linkages and its application for analyses of the synthetic products of ribonuclease T1 and spontaneous reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373440"}
{"pmid": "4373439", "title": "Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk).", "content": "Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk). Mutants of Salmonella typhimurium defective in cytidine 5'-monophosphate (CMP) kinase (cmk) have been isolated. The mutants also lack the ability to phosphorylate 2'-deoxyCMP, indicating that one enzyme is responsible for the phosphorylation of both CMP and deoxyCMP to the corresponding diphosphates. In glucose minimal medium the mutants grow at the same rate as the parental strain; however, they excrete large quantities of pyrimidines into the growth medium. Cytidine but not deoxycytidine has been identified among the excreted products. The mutant phenotype suggests that the physiological role of CMP kinase is that of rephosphorylating CMP arising from the breakdown of messenger ribonucleic acid. This proposed role of CMP kinase is supported by the fact that a cmk(-) mutant is much more sensitive to any partial impairment of cytidine 5'-triphosphate synthetase than is the cmk(+) parent strain. The gene cmk has been located on the Salmonella chromosome at 38.5 min. No markers which can be cotransduced with cmk by phage P22 have been found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373439"}
{"pmid": "4373441", "title": "Electron spin resonance study of the interaction between heavy meromyosin and Mn2 plus.", "content": "Electron spin resonance study of the interaction between heavy meromyosin and Mn2 plus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373441"}
{"pmid": "4373442", "title": "Energization of NTP-NDP kinase by acid-base transition leading to ATP formation.", "content": "Energization of NTP-NDP kinase by acid-base transition leading to ATP formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373442"}
{"pmid": "4373443", "title": "Phosphorylation of endogenous hepatic proteins by adenosine 3',5'-monophosphate-dependent protein kinase.", "content": "Phosphorylation of endogenous hepatic proteins by adenosine 3',5'-monophosphate-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373443"}
{"pmid": "4373444", "title": "Phosphodiesterase-phosphomonoesterases from Fusarium moniliforme. V. Mode of action on various nucleotides.", "content": "Phosphodiesterase-phosphomonoesterases from Fusarium moniliforme. V. Mode of action on various nucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373444"}
{"pmid": "4373445", "title": "Studies on mitochondrial and microsomal nucleoside diphosphatases of rat liver.", "content": "Studies on mitochondrial and microsomal nucleoside diphosphatases of rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373445"}
{"pmid": "4373446", "title": "Biochemical and topographical studies on the cell surface of Escherichia coli. I. Isolation and characterization of detergent-sensitive mutants.", "content": "Biochemical and topographical studies on the cell surface of Escherichia coli. I. Isolation and characterization of detergent-sensitive mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373446"}
{"pmid": "4373447", "title": "Kinetic studies on the inhibition of nucleoside diphosphate kinase by desdanine.", "content": "Kinetic studies on the inhibition of nucleoside diphosphate kinase by desdanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373447"}
{"pmid": "4373448", "title": "Pyruvate kinase of Escherichia coli. Its role in supplying nucleoside triphosphates in cells under anaerobic conditions.", "content": "Pyruvate kinase of Escherichia coli. Its role in supplying nucleoside triphosphates in cells under anaerobic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373448"}
{"pmid": "4373450", "title": "Interactions between elongation factor tu-guanosine triphosphate and ribosomes and the role of ribosome-bound transfer RNA in guanosine triphosphatase reaction.", "content": "Interactions between elongation factor tu-guanosine triphosphate and ribosomes and the role of ribosome-bound transfer RNA in guanosine triphosphatase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373450"}
{"pmid": "4373449", "title": "Conversion of glucose and galactose to lipids by normal and phytohemagglutinin-stimulated lymphocytes.", "content": "Conversion of glucose and galactose to lipids by normal and phytohemagglutinin-stimulated lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373449"}
{"pmid": "4373451", "title": "Positional specificity of sn-glycerol 3-phosphate acylation during phosphatidate formation by rat liver microsomes.", "content": "Positional specificity of sn-glycerol 3-phosphate acylation during phosphatidate formation by rat liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373451"}
{"pmid": "4373452", "title": "Structural studies on anti-inflammatory polysaccharides from Streptomyces fradiae.", "content": "Structural studies on anti-inflammatory polysaccharides from Streptomyces fradiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373452"}
{"pmid": "4373453", "title": "In vitro models for photosynthetic energy conversion.", "content": "In vitro models for photosynthetic energy conversion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373453"}
{"pmid": "4373454", "title": "Adenylate cyclase activity in fibroblasts transformed by Kirsten or Moloney sarcoma viruses. Decreased activity and loss of response to prostaglandin E1.", "content": "Adenylate cyclase activity in fibroblasts transformed by Kirsten or Moloney sarcoma viruses. Decreased activity and loss of response to prostaglandin E1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373454"}
{"pmid": "4373455", "title": "Characterization of the 4 S and 5 S forms of the estradiol receptor protein and their interaction with deoxyribonucleic acid.", "content": "Characterization of the 4 S and 5 S forms of the estradiol receptor protein and their interaction with deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373455"}
{"pmid": "4373456", "title": "On the specificity of the binding of the estradiol receptor protein to deoxyribonucleic acid.", "content": "On the specificity of the binding of the estradiol receptor protein to deoxyribonucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373456"}
{"pmid": "4373457", "title": "Structural requirements for recognition of Escherichia coli initiator and non-initiator transfer ribonucleic acids by bacterial T factor.", "content": "Structural requirements for recognition of Escherichia coli initiator and non-initiator transfer ribonucleic acids by bacterial T factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373457"}
{"pmid": "4373458", "title": "Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. I. Evidence for an ecto-adenosine monophosphatase, adenosine triphosphatase, and -p-nitrophenyl phosphates.", "content": "Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. I. Evidence for an ecto-adenosine monophosphatase, adenosine triphosphatase, and -p-nitrophenyl phosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373458"}
{"pmid": "4373459", "title": "Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. II. Properties and suitability as markers for the plasma membrane.", "content": "Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. II. Properties and suitability as markers for the plasma membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373459"}
{"pmid": "4373460", "title": "Purification and characterization of an inhibitor of elongation factor G-dependent guanosine triphosphatase reaction of ribosomes from ribosome wash of Escherichia coli Q13.", "content": "Purification and characterization of an inhibitor of elongation factor G-dependent guanosine triphosphatase reaction of ribosomes from ribosome wash of Escherichia coli Q13.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373460"}
{"pmid": "4373461", "title": "Rapid reciprocal changes in rat hepatic glycolytic enzyme and fructose diphosphatase activities following insulin and glucagon injection.", "content": "Rapid reciprocal changes in rat hepatic glycolytic enzyme and fructose diphosphatase activities following insulin and glucagon injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373461"}
{"pmid": "4373462", "title": "Rapid reciprocal changes in rat tissue enzyme activities following epinephrine injection.", "content": "Rapid reciprocal changes in rat tissue enzyme activities following epinephrine injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373462"}
{"pmid": "4373464", "title": "Total reconstitution of copper-zinc superoxide dismutase.", "content": "Total reconstitution of copper-zinc superoxide dismutase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373464"}
{"pmid": "4373463", "title": "Structure of the carbohydrate units of IgA1 immunoglobulin. II. Structure of the O-glycosidically linked oligosaccharide units.", "content": "Structure of the carbohydrate units of IgA1 immunoglobulin. II. Structure of the O-glycosidically linked oligosaccharide units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373463"}
{"pmid": "4373465", "title": "Lipogenesis by acini from mammary gland of lactating rats.", "content": "Lipogenesis by acini from mammary gland of lactating rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373465"}
{"pmid": "4373466", "title": "The interaction of polypeptide components of human high density serum lipoprotein with detergents.", "content": "The interaction of polypeptide components of human high density serum lipoprotein with detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373466"}
{"pmid": "4373467", "title": "The decline of molecular activity of cytochrome oxidase during purification.", "content": "The decline of molecular activity of cytochrome oxidase during purification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373467"}
{"pmid": "4373468", "title": "Studies on ribonucleic acid ligase. Characterization of an adenosine triphosphate-inorganic pyrophosphate exchange reaction and demonstration of an enzyme-adenylate complex with T4 bacteriophage-induced enzyme.", "content": "Studies on ribonucleic acid ligase. Characterization of an adenosine triphosphate-inorganic pyrophosphate exchange reaction and demonstration of an enzyme-adenylate complex with T4 bacteriophage-induced enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373468"}
{"pmid": "4373469", "title": "Ornithine cyclase (deaminating). II. Properties of the homogeneous enzyme.", "content": "Ornithine cyclase (deaminating). II. Properties of the homogeneous enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373469"}
{"pmid": "4373470", "title": "Activation of hexose transport by concanavalin A in isolated brown fat cells. Effects of cell surface modification with neuraminidase and trypsin on lectin and insulin action.", "content": "Activation of hexose transport by concanavalin A in isolated brown fat cells. Effects of cell surface modification with neuraminidase and trypsin on lectin and insulin action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373470"}
{"pmid": "4373471", "title": "Studies on calciferol metabolism. IX. Renal 25-hydroxy-vitamin D3-1 hydroxylase. Involvement of cytochrome P-450 and other properties.", "content": "Studies on calciferol metabolism. IX. Renal 25-hydroxy-vitamin D3-1 hydroxylase. Involvement of cytochrome P-450 and other properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373471"}
{"pmid": "4373472", "title": "An iron-containing phosphatase induced by progesterone in the uterine fluids of pigs.", "content": "An iron-containing phosphatase induced by progesterone in the uterine fluids of pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373472"}
{"pmid": "4373473", "title": "Regulation of 25-hydroxyvitamin D3-1-hydroxylase in vivo.", "content": "Regulation of 25-hydroxyvitamin D3-1-hydroxylase in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373473"}
{"pmid": "4373474", "title": "Formaldehyde dehydrogenase from human liver. Purification, properties, and evidence for the formation of glutathione thiol esters by the enzyme.", "content": "Formaldehyde dehydrogenase from human liver. Purification, properties, and evidence for the formation of glutathione thiol esters by the enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373474"}
{"pmid": "4373475", "title": "Hydroxylysine-deficient skin collagen in a patient with a form of the Ehlers-Danlos syndrome.", "content": "Hydroxylysine-deficient skin collagen in a patient with a form of the Ehlers-Danlos syndrome. Two sibs with the Ehlers-Danlos syndrome, one of whom was shown to have hydroxylysine-deficient collagen, are described. In addition to the usual features of the Ehlers-Danlos syndrome (loose-jointedness and excessively stretchable, fragile, and bruisable skin), these patients had severe scoliosis and fragility of ocular tissues leading to rupture of the globe or retinal detachment. This combination of symptoms was tentatively classified as Ehlers-Danlos syndrome, Type VI. The condition is inherited as an autosomal recessive. The activity of lysyl hydroxylase was present at a reduced level in fibroblasts cultured from the patient's skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373475"}
{"pmid": "4373478", "title": "Food vacuole membrane growth with microtubule-associated membrane transport in Paramecium.", "content": "Food vacuole membrane growth with microtubule-associated membrane transport in Paramecium. Evidence from a morphological study of the oral apparatus of Paramecium caudatum using electron microscope techniques have shown the existence of an elaborate structural system which is apparently designed to recycle digestive-vacuole membrane. Disk-shaped vesicles are filtered out of the cytoplasm by a group of microtubular ribbons. The vesicles, after being transported to the cytostome-cytopharynx region in association with these ribbons, accumulate next to the cytopharynx before they become fused with the cytopharyngeal membrane. This fusion allows the nascent food vacuole to grow and increase its membrane surface area. The morphology of this cytostome-cytopharynx region is described in detail and illustrated with a three-dimensional drawing of a portion of this region and a clay sculpture of the oral apparatus of Paramecium. Evidence from the literature for the transformation of food vacuole membrane into disk-shaped vesicles both from condensing food vacuoles in the endoplasm and from egested food vacuoles at the cytoproct is presented. This transformation would complete a system of digestive vacuole membrane recycling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373478"}
{"pmid": "4373477", "title": "Studies on dispersed pancreatic exocrine cells. I. Dissociation technique and morphologic characteristics of separated cells.", "content": "Studies on dispersed pancreatic exocrine cells. I. Dissociation technique and morphologic characteristics of separated cells. A procedure for dissociation of the guinea pig pancreas into individual cells is described which employs enzymatic digestion with pure collagenase, chymotrypsin, and hyaluronidase, utilizes an interposed chelation of divalent cations by EDTA, and is terminated by gentle shearing. Yields of cells are 50-60%, based on DNA recovered. The population comprises approximately 95% exocrine cells, the remainder consisting of endocrine, duct, and vascular endothelial cells. The exocrine cells, though spherical, retain the structural attributes of their in situ counterparts, including differentiation of the plasmalemma into zones corresponding to the former apical and basal plasmalemma, polarized distribution of organelles indicated by fields of zymogen granules in the cytoplasm underlying the former apex, central location of the Golgi complex, and placement of the rough endoplasmic reticulum and nucleus in the former basal pole of the cell. Electron microscope study of the effects of individual treatments used during dissociation indicates that digestion of basement membrane and collagen is solely due to collagenase activity and that separation of desmosomes (and possibly of zonulae adherentes) results only from exposure to low [Ca(++)] and EDTA and is not effected by the enzymes used. Gap junctions are resistant to enzymes and EDTA; tight junctions resist enzyme treatment but undergo rearrangement upon exposure to EDTA. Both junctions require mechanical shear for complete cell separation. Neither chymotrypsin nor hyaluronidase produces visible alterations in stromal or junctional elements. Dissociation requires the concerted action of enzymes, chelation of divalent cations, and mechanical shear, since the individual treatments are alone ineffective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373477"}
{"pmid": "4373479", "title": "Effects of cytochalasin B on the response of toad urinary bladder to vasopressin.", "content": "Effects of cytochalasin B on the response of toad urinary bladder to vasopressin. A combined physiological and morphological study of the effects of cytochalasin B (CB) on the toad urinary bladder has been carried out. CB inhibits the hydro-osmotic response to vasopressin without altering basal water permeability or diffusion, or the increase in (3)H(2)O diffusion observed after hormone addition. Although CB increases [(22)Na]-, [(36)Cl]-, and [(14)C]urea fluxes, and decreases transepithelial potential, no alteration in basal short-circuit current, the vasopressin-induced increase in this parameter, or [(14)C]inulin permeability occurs. In the absence of hormone, CB does not markedly alter the structure of the toad bladder. However, in the presence of vasopressin, CB induces the formation of large intracellular vacuoles. These results suggest a possible coupling of solute and water movement across the tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373479"}
{"pmid": "4373481", "title": "Metabolic cooperation in cell culture: studies of the mechanisms of cell interaction.", "content": "Metabolic cooperation in cell culture: studies of the mechanisms of cell interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373481"}
{"pmid": "4373480", "title": "Analysis of the pinocytic process in rat kidney. I. Isolation of pinocytic vesicles from rat kidney cortex.", "content": "Analysis of the pinocytic process in rat kidney. I. Isolation of pinocytic vesicles from rat kidney cortex. Pinocytosis was induced in rat kidney by exposure to horseradish peroxidase (HRP). Pinocytic vesicle preparations were enriched after homogenization of kidney cortex by differential centrifugation and free-flow electrophoresis with HRP as an exogenous marker. Vesicles were identified by enzymatic analysis and by electron microscopy, including specific staining procedures. Typical brush-border enzymes such as alkaline phosphatase, aminopeptidase, 5'-nucleotidase, lysosomal acid phosphatase, and mitochondrial succinic dehydrogenase were reduced in the vesicular fraction, compared to the kidney cortex homogenate. Glucose-6-phosphatase and Na(+)-K(+)-ATPase were only slightly increased in the fraction. These results indicate that preparations of pinocytic vesicles from rat kidney cortex can be enriched. They have biochemical characteristics that differ from those of the cell organelles and membranes previously purified from renal tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373480"}
{"pmid": "4373482", "title": "Release of cytoplasmic enzymes into culture fluid.", "content": "Release of cytoplasmic enzymes into culture fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373482"}
{"pmid": "4373483", "title": "In vitro response of goldfish (Carassius auratus L.) dermal melanophores to cyclic 3',5'-nucleotides, nucleoside 5'-phosphates and methylxanthines.", "content": "In vitro response of goldfish (Carassius auratus L.) dermal melanophores to cyclic 3',5'-nucleotides, nucleoside 5'-phosphates and methylxanthines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373483"}
{"pmid": "4373476", "title": "Extracorporeal circulation with and without magnesium. An experimental study.", "content": "Extracorporeal circulation with and without magnesium. An experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373476"}
{"pmid": "4373484", "title": "Effect of cAMP on nucleoside metabolism. II. Cell cycle dependence of thymidine transport.", "content": "Effect of cAMP on nucleoside metabolism. II. Cell cycle dependence of thymidine transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373484"}
{"pmid": "4373485", "title": "Cell cycle dependent modulations of the surface membrane of normal and SV40 virus transformed 3T3 cells.", "content": "Cell cycle dependent modulations of the surface membrane of normal and SV40 virus transformed 3T3 cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373485"}
{"pmid": "4373487", "title": "A temperature-sensitive cell cycle mutant of the BHK cell line.", "content": "A temperature-sensitive cell cycle mutant of the BHK cell line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373487"}
{"pmid": "4373486", "title": "Cellular binding of 3H-cytochalasin B.", "content": "Cellular binding of 3H-cytochalasin B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373486"}
{"pmid": "4373488", "title": "Concanavalin A and the initiation of thymic lymphoblast DNA synthesis and proliferation by a calcium-dependent increase in cyclic GMP level.", "content": "Concanavalin A and the initiation of thymic lymphoblast DNA synthesis and proliferation by a calcium-dependent increase in cyclic GMP level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373488"}
{"pmid": "4373489", "title": "Agglutination by concanavalin A of normal chick embryo fibroblasts treated by 5-bromodeoxyuridine (BrdU).", "content": "Agglutination by concanavalin A of normal chick embryo fibroblasts treated by 5-bromodeoxyuridine (BrdU).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373489"}
{"pmid": "4373490", "title": "Editorial: Hypothalmic neurohumors and pituitary tumors.", "content": "Editorial: Hypothalmic neurohumors and pituitary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373490"}
{"pmid": "4373491", "title": "Bile acid kinetics in relation to sex, serum lipids, body weights, and gallbladder disease in patients with various types of hyperlipoproteinemia;.", "content": "Bile acid kinetics in relation to sex, serum lipids, body weights, and gallbladder disease in patients with various types of hyperlipoproteinemia;. Bile acid kinetics were determined in 15 normolipidemic and 61 hyperlipidemic subjects with the aid of [(14)C]cholic acid and [(3)H]chenodeoxycholic acid. The diet was standardized and of natural type. The total bile acid formation was within normal limits in patients with hyperlipoproteinemia types IIa and IIb. On the average the production of cholic acid (C) represented less than 50% of the total bile acid synthesis in both groups. The corresponding value recorded for the controls was 64+/-2% (mean+/-SEM). The synthesis of C in hyperlipoproteinemia type IIa was significantly below normal. Of the 27 patients with the type IV pattern, 18 had a synthesis of C and C + chenodeoxycholic acid (CD) that exceeded the upper range recorded for the controls. In these subjects the C formation represented 73+/-3% of the total bile acid synthesis. Similar findings were also encountered in the five patients with the type V lipoprotein pattern studied. The bile acid pool size of the 11 patients with hyperlipoproteinemia type IV, who had been cholecystectomized or suffered from cholelithiasis, was 900 mg smaller on the average than that of the other subjects with the same type of hyperlipoproteinemia. However, the pool size in the former subjects still tended to be higher than that of the control subjects without evidence of gallbladder \"disease\". In all groups of subjects the formation of bile acids tended to be higher in the male than in the female subjects. Bile acid synthesis showed no linear correlation to actual body weight, relative body weight, or body surface area. A moderate weight reduction in five patients (one with type IIb and four with type IV pattern) was followed by a 50% reduction of the C and CD synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373491"}
{"pmid": "4373492", "title": "The secondary structure of human Hageman factor (factor XII) and its alteration by activating agents.", "content": "The secondary structure of human Hageman factor (factor XII) and its alteration by activating agents. Hageman factor (factor XII) is activated by exposure to surfaces such as glass or by solutions of certain compounds, notably ellagic acid. Changes in the structure of Hageman factor accompanying activation have been examined in this study by circular dichroism spectroscopy. The spectrum of unactivated Hageman factor in aqueous solutions suggests that its conformation is mainly aperiodic. Various perturbants altered the conformation of Hageman factor in differing ways, demonstrating the sensitivity of Hageman factor to its environment. After activation of Hageman factor with solutions of ellagic acid, a negative trough appeared in the region of the circular dichroism spectrum commonly assigned to tyrosine residues, along with other minor changes in the peptide spectral region. Some of these changes are similar to changes that occurred upon partial neutralization of the basic residues at alkali pH. Activation of Hageman factor by adsorption to quartz surfaces (in an aqueous environment) also produced changes similar to those in the ellagic acid-activated Hageman factor, including the negative ellipticity in the tyrosine region. These observations suggest that the activation process may be related to a change in status of some of the basic amino acid residues, coupled with a specific change in the environment of some tyrosine residues. The importance of these changes during the activation process remains to be determined. The sensitivity of Hageman factor to its environment is consistent with the view that the initiation of clotting by exposure of plasma to appropriate agents is brought about by alterations in the conformation of Hageman factor that occur in the apparent absence of Fletcher factor or other recognized clotting factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373492"}
{"pmid": "4373495", "title": "Letter: Dynamics and thermodynamics of axial ligation in metalloporphyrins. 3. Effects of molecular interaction of ferric porphyrins with an aromatic acceptor.", "content": "Letter: Dynamics and thermodynamics of axial ligation in metalloporphyrins. 3. Effects of molecular interaction of ferric porphyrins with an aromatic acceptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373495"}
{"pmid": "4373493", "title": "Superficial and deep juxtaglomerular apparatus renin activity of the rat kidney. Effect of surgical preparation and NaCl intake.", "content": "Superficial and deep juxtaglomerular apparatus renin activity of the rat kidney. Effect of surgical preparation and NaCl intake. The intrarenal gradient of renin activity was determined in rats by using superficial (S) and deep (D) cortical juxtaglomerular apparatuses (JGA's), identified and microdissected after silicone-rubber compound injection. Angiotensin generated from single JGA's using partially purified sheep renin substrate was quantified by rat bioassay. When, in rats on a normal NaCl diet, silicone-rubber was injected into a carotid artery, alone or with abdominal aorta catheterization, S:D renin activity ratios were 1.18+/-0.08 (SEM) and 1.21+/-0.12, respectively. The S:D renin activity ratios obtained when silicone-rubber was injected into the abdominal aorta (2.52+/-0.09) or a chronic carotid artery catheter (3.44+/-0.40) were significantly higher (P < 0.001). The lower S:D renin activity ratios after carotid artery manipulation were due to significantly higher D-JGA renin activities. This increased D-JGA renin activity and the lack of a renin gradient appear to be related to acute carotid artery manipulation. Alterations in JGA renin activity were examined relative to NaCl intake. 2 wk after high-NaCl diet the absolute net renin activity decreased (P < 0.001) more in S (5.84+/-0.11 ng AI.JGA(-1).h(-1)) than D (1.73+/-0.06 ng AI.JGA(-1).h(-1)) JGA's, and the intrarenal renin gradient was lost (S:D-JGA renin activity, 1.00+/-0.07), as compared to the regular NaCl diet. 2 wk of a low-NaCl diet resulted in a greater (P < 0.01) increase in S (14.28+/-1.47 ng AI.JGA(-1).h(-1)) than D (9.62+/-1.19 ng AI.JGA(-1).h(-1)) JGA renin activity and a renin gradient (S:D-JGA renin activity) of 1.75+/-0.12. These results demonstrate that NaCl intake clearly influences total JGA renin content and may also affect the relative intrarenal distribution of renin activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373493"}
{"pmid": "4373496", "title": "Letter: Lanthanide porphyrin complexes. A potential new class of nuclear magnetic resonance dipolar probe.", "content": "Letter: Lanthanide porphyrin complexes. A potential new class of nuclear magnetic resonance dipolar probe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373496"}
{"pmid": "4373494", "title": "Glucagon secretion from the perfused rat pancreas. Studies with glucose and catecholamines.", "content": "Glucagon secretion from the perfused rat pancreas. Studies with glucose and catecholamines. The isolated in situ perfused rat pancreas was used to study glucose and catecholamine control of glucagon secretion, and to investigate the possible role of endogenous cyclic AMP as a mediator of this secretory process. When perfusate glucose was acutely dropped from 100 to 25 mg/100 ml, glucagon was released in a biphasic pattern with an early spike and a later plateau-like response. 300 mg/100 ml glucose suppressed glucagon secretion to near the detection limit of the radioimmunoassay (15 pg/ml). When perfusate glucose was dropped from 300 to 25 mg/100 ml, a delayed, relatively small peak occurred suggesting persisting alpha cell suppression by prior high glucose exposure. 2-Deoxy d-glucose stimulated glucagon secretion and inhibited insulin secretion. Glucagon was secreted in a biphasic pattern in response to both 2.7 x 10(-7) M epinephrine and norepinephrine. The glucagon response to epinephrine was markedly suppressed by glucose at 300 mg/100 ml, and the biphasic response pattern was obliterated. Glucose evoked a two-phase insulin secretory pattern, and the second phase was markedly and rapidly inhibited by epinephrine. Pancreases were perfused with glucose at 300 mg/100 ml which was then lowered to 80 mg/100 ml. 5 min later, epinephrine was infused and definite blunting of the first-phase spike occurred. 10 mM theophylline produced modest rapid uniphasic stimulation of glucagon release, and, in addition, caused enhancement of epinephrine-stimulated glucagon release. An inhibitory influence upon epinephrine-stimulated glucagon was observed as well. Insulin secretion was stimulated by 10 mM theophylline, and this stimulation was inhibited by epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373494"}
{"pmid": "4373497", "title": "Growth and development of children maintained on total parenteral nutrition in the neonatal period.", "content": "Growth and development of children maintained on total parenteral nutrition in the neonatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373497"}
{"pmid": "4373498", "title": "AMWA--six decades of progress (in the serivice of women in medicine).", "content": "AMWA--six decades of progress (in the serivice of women in medicine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373498"}
{"pmid": "4373499", "title": "Future aspects of the American Medical Women's Association.", "content": "Future aspects of the American Medical Women's Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373499"}
{"pmid": "4373500", "title": "Malnutrition and infection. Malaria, cholera and influenza in Africa.", "content": "Malnutrition and infection. Malaria, cholera and influenza in Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373500"}
{"pmid": "4373501", "title": "Edith L. Potter, M.D.--pathologist.", "content": "Edith L. Potter, M.D.--pathologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373501"}
{"pmid": "4373502", "title": "Letter: To: Women concerned about health care.", "content": "Letter: To: Women concerned about health care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373502"}
{"pmid": "4373504", "title": "A heat-digestible cell-immunoadsorbent made by coupling hapten to gelatin.", "content": "A heat-digestible cell-immunoadsorbent made by coupling hapten to gelatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373504"}
{"pmid": "4373505", "title": "Drug induced depression.", "content": "Drug induced depression. Some of the drugs that tend to cause mental depression are antihypertensive drugs, ACTH and cortisone, and oral contraceptives (OCs).  OCs containing progestogen-estrogen cause depression on occasion.  Various mechanisms have been invoked to explain this contraceptive hormone induced depression.  Although interference with tryptophan metabolism has been advanced, depression seems to be consequent to the accelerated monoamine resulting in its decreased availability at the synaptic level.  Baumblatt and Winston recommended pyridoxine 50 mg daily to overcome psychiatric effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373505"}
{"pmid": "4373506", "title": "Amoebiasis with pericardial involvement.", "content": "Amoebiasis with pericardial involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373506"}
{"pmid": "4373507", "title": "The post-mortem diagnosis of Japanese encephalitis.", "content": "The post-mortem diagnosis of Japanese encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373507"}
{"pmid": "4373508", "title": "Seminars from Riley Children's Hospital. Recent developments in treatment of childhood cancer. II.", "content": "Seminars from Riley Children's Hospital. Recent developments in treatment of childhood cancer. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373508"}
{"pmid": "4373503", "title": "Testes structure in normal and parthenogenetic turkeys.", "content": "Testes structure in normal and parthenogenetic turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373503"}
{"pmid": "4373513", "title": "Pseudomonas tracheobronchitis. The use of systemic gentamicin and polymyxin-B aerosol.", "content": "Pseudomonas tracheobronchitis. The use of systemic gentamicin and polymyxin-B aerosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373513"}
{"pmid": "4373514", "title": "Fasting hypoglycemia. Diazoxide as a test for endogenous insulin release.", "content": "Fasting hypoglycemia. Diazoxide as a test for endogenous insulin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373514"}
{"pmid": "4373515", "title": "The primary hyperlipoproteinemias.", "content": "The primary hyperlipoproteinemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373515"}
{"pmid": "4373516", "title": "Intracellular actions of 5-hydroxytryptamine on the bivalve myocardium. II. Cyclic nucleotide-dependent protein kinases and microsomal calcium uptake.", "content": "Intracellular actions of 5-hydroxytryptamine on the bivalve myocardium. II. Cyclic nucleotide-dependent protein kinases and microsomal calcium uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373516"}
{"pmid": "4373518", "title": "Characteristics of enterotoxigenic Clostridium perfringens type A isolated from cattle and chickens.", "content": "Characteristics of enterotoxigenic Clostridium perfringens type A isolated from cattle and chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373518"}
{"pmid": "4373517", "title": "Improved culture techniques and sporulation medium for enterotoxin production by Clostridium perfringens type A.", "content": "Improved culture techniques and sporulation medium for enterotoxin production by Clostridium perfringens type A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373517"}
{"pmid": "4373519", "title": "Circular resection of the trachea for malignant and benign diseases.", "content": "Circular resection of the trachea for malignant and benign diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373519"}
{"pmid": "4373522", "title": "Formation of phospholipase C and theta-haemolysin in pre-reduced media in batch anc continuous culture of Clostridium perfringens type A.", "content": "Formation of phospholipase C and theta-haemolysin in pre-reduced media in batch anc continuous culture of Clostridium perfringens type A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373522"}
{"pmid": "4373523", "title": "Isoprenoid alcohol kinase--a third butanol-soluble enzyme in Klebsiella aerogenes membranes.", "content": "Isoprenoid alcohol kinase--a third butanol-soluble enzyme in Klebsiella aerogenes membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373523"}
{"pmid": "4373524", "title": "Ultrastructure of a marine Thiobacillus.", "content": "Ultrastructure of a marine Thiobacillus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373524"}
{"pmid": "4373525", "title": "Growth inhibition of Acetobacter aceti by L-threonine and l-Homoserine: the primary regulation of the biosynthesis of amino acids of the aspartate family.", "content": "Growth inhibition of Acetobacter aceti by L-threonine and l-Homoserine: the primary regulation of the biosynthesis of amino acids of the aspartate family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373525"}
{"pmid": "4373526", "title": "The effects of beta-galactosidase activity and cyclic AMP on lactose-accelerated death.", "content": "The effects of beta-galactosidase activity and cyclic AMP on lactose-accelerated death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373526"}
{"pmid": "4373527", "title": "Inhibition by ethidium bromide of the establishment of infection by murine sarcoma virus.", "content": "Inhibition by ethidium bromide of the establishment of infection by murine sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373527"}
{"pmid": "4373528", "title": "The effect of isatin beta thiosemicarbazone (IBT)-related compounds on IBT-resistant and on IBT-dependent mutants of vaccinia virus.", "content": "The effect of isatin beta thiosemicarbazone (IBT)-related compounds on IBT-resistant and on IBT-dependent mutants of vaccinia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373528"}
{"pmid": "4373529", "title": "Aminoacylation of RNA from several viruses: amino acid specificity and differential activity of plant, yeast and bacterial synthetases.", "content": "Aminoacylation of RNA from several viruses: amino acid specificity and differential activity of plant, yeast and bacterial synthetases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373529"}
{"pmid": "4373530", "title": "The cytopathic effect of herpes simplex virus on HEp-2 cells as shown by scanning electron microscopy.", "content": "The cytopathic effect of herpes simplex virus on HEp-2 cells as shown by scanning electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373530"}
{"pmid": "4373532", "title": "Correlation between ultrastructural and electrophysiological signs of degeneration in optic nerve terminals of the cat's lateral geniculate nucleus.", "content": "Correlation between ultrastructural and electrophysiological signs of degeneration in optic nerve terminals of the cat's lateral geniculate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373532"}
{"pmid": "4373531", "title": "Peripheral serotonin antagonists: failure to antagonize serotonin in brain areas receiving a prominent serotonergic input.", "content": "Peripheral serotonin antagonists: failure to antagonize serotonin in brain areas receiving a prominent serotonergic input.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373531"}
{"pmid": "4373533", "title": "Cyclic AMP and amine effects on phosphorylation of specific protein in abdominal ganglion of Aplysia californica; localization and kinetic analysis.", "content": "Cyclic AMP and amine effects on phosphorylation of specific protein in abdominal ganglion of Aplysia californica; localization and kinetic analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373533"}
{"pmid": "4373534", "title": "Activity patterns of catecholamine-containing pontine neurons in the dorso-lateral tegmentum of unrestrained cats.", "content": "Activity patterns of catecholamine-containing pontine neurons in the dorso-lateral tegmentum of unrestrained cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373534"}
{"pmid": "4373535", "title": "Antifacilitating and simple following responses in a single motoneuron.", "content": "Antifacilitating and simple following responses in a single motoneuron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373535"}
{"pmid": "4373536", "title": "The uptake of 36C1 into astrocytes in tissue culture by a potassium-dependent, saturable process.", "content": "The uptake of 36C1 into astrocytes in tissue culture by a potassium-dependent, saturable process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373536"}
{"pmid": "4373537", "title": "The characterization of sphingolipids from neurons and astroglia of immature rat brain.", "content": "The characterization of sphingolipids from neurons and astroglia of immature rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373537"}
{"pmid": "4373538", "title": "Phosphatidyl inositol turnover in muscle membranes following denervation.", "content": "Phosphatidyl inositol turnover in muscle membranes following denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373538"}
{"pmid": "4373539", "title": "Hydrolytic enzyme activities in the developing chick central and peripheral nervous systems.", "content": "Hydrolytic enzyme activities in the developing chick central and peripheral nervous systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373539"}
{"pmid": "4373540", "title": "Preparation of synaptosomes and vesicles with sodium diatrizoate.", "content": "Preparation of synaptosomes and vesicles with sodium diatrizoate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373540"}
{"pmid": "4373541", "title": "The cytotoxicity of D-galactosamine in cat spinal cord.", "content": "The cytotoxicity of D-galactosamine in cat spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373541"}
{"pmid": "4373542", "title": "The ultrastructure of retinula cell endings in the compound eye of the crayfish.", "content": "The ultrastructure of retinula cell endings in the compound eye of the crayfish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373542"}
{"pmid": "4373543", "title": "Interneurons of the sympathetic ganglia, in organotypic culture. A suggestion as to their function, based on three types of study.", "content": "Interneurons of the sympathetic ganglia, in organotypic culture. A suggestion as to their function, based on three types of study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373543"}
{"pmid": "4373544", "title": "The fate of the axon and its terminal in the Pacinian corpuscle following sciatic nerve section.", "content": "The fate of the axon and its terminal in the Pacinian corpuscle following sciatic nerve section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373544"}
{"pmid": "4373545", "title": "Neuroglial cells in the cerebral cortex of rats from young adulthood to old age: an electron microscope study.", "content": "Neuroglial cells in the cerebral cortex of rats from young adulthood to old age: an electron microscope study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373545"}
{"pmid": "4373546", "title": "Synaptic inhibition in pyramidal tract neurons: membrane potential and conductance changes evoked by pyramidal tract and cortical surface stimulation.", "content": "Synaptic inhibition in pyramidal tract neurons: membrane potential and conductance changes evoked by pyramidal tract and cortical surface stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373546"}
{"pmid": "4373547", "title": "Motor organization and generation of rhythmic feeding output in buccal ganglion of Pleurobranchaea.", "content": "Motor organization and generation of rhythmic feeding output in buccal ganglion of Pleurobranchaea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373547"}
{"pmid": "4373548", "title": "Effects of projected cortical epileptiform discharges on neuronal activities in cat VPL. I. Interictal discharge.", "content": "Effects of projected cortical epileptiform discharges on neuronal activities in cat VPL. I. Interictal discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373548"}
{"pmid": "4373550", "title": "Effect of amino acid supplement on liver lipid content and lipid metabolism of rats fed a nonprotein diet.", "content": "Effect of amino acid supplement on liver lipid content and lipid metabolism of rats fed a nonprotein diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373550"}
{"pmid": "4373549", "title": "Active transport of thiamine from rat small intestine.", "content": "Active transport of thiamine from rat small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373549"}
{"pmid": "4373551", "title": "Purification and properties of quinolinate phosphoribosyltransferase from the \"Shiitake\" mushroom (Lentinus edodes).", "content": "Purification and properties of quinolinate phosphoribosyltransferase from the \"Shiitake\" mushroom (Lentinus edodes).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373551"}
{"pmid": "4373552", "title": "Characteristics of quinolinate phosphoribosyltransferase from the \"Shiitake\" mushroom (Lentinus edodes).", "content": "Characteristics of quinolinate phosphoribosyltransferase from the \"Shiitake\" mushroom (Lentinus edodes).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373552"}
{"pmid": "4373553", "title": "Preventive effect of riboflavin 2',3',4',5'-tetrabutyrate on inactivation of rat liver microsomal enzymes induced by carbon tetrachloride.", "content": "Preventive effect of riboflavin 2',3',4',5'-tetrabutyrate on inactivation of rat liver microsomal enzymes induced by carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373553"}
{"pmid": "4373554", "title": "The mechanism of action of oestrogen in the human female.", "content": "The mechanism of action of oestrogen in the human female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373554"}
{"pmid": "4373559", "title": "Cystic adenoma of a minor salivary gland: a histochemical study.", "content": "Cystic adenoma of a minor salivary gland: a histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373559"}
{"pmid": "4373558", "title": "Enzyme patterns in non-neoplastic and spontaneously transformed tissue culture cells: a histochemical and biochemical study.", "content": "Enzyme patterns in non-neoplastic and spontaneously transformed tissue culture cells: a histochemical and biochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373558"}
{"pmid": "4373560", "title": "Extensive calcification in the stroma of a primary hepatic carcinoma.", "content": "Extensive calcification in the stroma of a primary hepatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373560"}
{"pmid": "4373561", "title": "Microsporidan infection of Simulium damnosum in West Africa.", "content": "Microsporidan infection of Simulium damnosum in West Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373561"}
{"pmid": "4373555", "title": "Swellings of the salivary glands. Part II, neoplasms.", "content": "Swellings of the salivary glands. Part II, neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373555"}
{"pmid": "4373564", "title": "Letter: Bioavailability of digoxin in presence of antacids.", "content": "Letter: Bioavailability of digoxin in presence of antacids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373564"}
{"pmid": "4373563", "title": "Synthetic procedures for deuterium-labeled acetylcholine perchlorates.", "content": "Synthetic procedures for deuterium-labeled acetylcholine perchlorates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373563"}
{"pmid": "4373565", "title": "Letter: Nonaqueous titration of procainamide hydrochloride.", "content": "Letter: Nonaqueous titration of procainamide hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373565"}
{"pmid": "4373566", "title": "Renin and angiotensin-like levels in foetal, new-born and adult sheep.", "content": "Renin and angiotensin-like levels in foetal, new-born and adult sheep. 1. Plasma renin (measured as rate of formation of angiotensin I ng/ml.hr(-1) in the presence of added substrate at pH 7.5 and 37 degrees C) was much lower in recently nephrectomized foetal, new-born and older lambs than in intact siblings or other similar lambs.2. Angiotensin II-like concentrations were measured using a superfusion technique in an extracorporeal circuit. Resting concentrations in acute experiments under anaesthesia were deduced by comparison of carotid blood of intact lambs with that from recently nephrectomized lambs.3. Angiotensin II-like activity (mean +/- S.E. of mean, 315 +/- 117 pg/ml.) was readily detectable in foetal blood at 123-138 days gestation. The highest concentrations (mean +/- S.E. of mean 839 +/- 96 pg/ml.) were found in lambs less than 8 hr old, delivered vaginally. The lowest concentrations of angiotensin II-like activity occurred in lambs delivered by Caesarean section (mean +/- S.E. of mean < 123 +/- 12 pg/ml.). Concentrations declined with post-natal age.4. Hypovolaemia as a result of haemorrhage evoked an increase in angiotensin II-like concentrations in foetus, new-born lambs and adult sheep. The greatest increase of angiotensin-like concentrations was seen in new-born lambs. This rise was associated with increase of plasma renin.5. The rise of arterial pressure during bilateral carotid occlusion in new-born lambs was accompanied by an increase of angiotensin II-like concentration.6. It is concluded that the renin-angiotensin system is functional and can be stimulated during intra-uterine life. The increase of angiotensin II-like concentration following parturition is probably transient and associated with the trauma of delivery. This contrasts with observations made in the rabbit which suggest that full functional maturity of the renin angiotensin system is delayed until the second week of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373566"}
{"pmid": "4373567", "title": "Synapse formation during embryogenesis on ganglion cells lacking a periphery.", "content": "Synapse formation during embryogenesis on ganglion cells lacking a periphery. 1. The development of transmission was studied in chick ciliary ganglia that had been deprived of their periphery during early embryonic development.2. Peripherally deprived neurones in the ganglion differentiate in normal numbers and send functional axons into the post-ganglionic nerve.3. Ganglion cells lacking a periphery follow the normal developmental sequence sending out transient dendrites at the time ganglion cell synapses are formed, and later retracting them when calyces appear.4. Synapses, which appear functionally and ultrastructurally normal, form on all ganglion cells at the normal time and transmission is normal until Stage 34. Therefore information from the periphery is not required for ganglion cell synapse formation per se.5. From Stages 35 to 38 most cells die, so that only 8% of the original number of cells remain in the operated ganglion. Transmission fails in many cells during this same time, but precedes cell loss by only a short time, so that deafferentation probably does not contribute substantially to cell death.6. Both ciliary and choroid cells achieve full cytologic differentiation and are distinct from each other, indicating that the periphery is not required for the elaboration of the distinctive characteristics of these cells. Presynaptic fibres also differentiate into typical bouton as well as calyciform endings. Therefore, the type of preganglionic ending does not depend on ganglion cells establishing proper peripheral contacts.7. It has not been possible to ascertain whether ganglion cell specificity is affected by the periphery.8. Peripheral removal affects ganglion cell migration, so that two ganglia are formed. Approximately half of the cells migrate into the remnant optic cup forming a second misplaced ganglion. Ciliary and choroid cells occur in both ganglia and these cells go through the typical sequence of events described above.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373567"}
{"pmid": "4373568", "title": "Synaptic transmission and cell death during normal ganglionic development.", "content": "Synaptic transmission and cell death during normal ganglionic development. 1. During normal embryonic development of the chick ciliary ganglion, cell death over a 4-day period (Stages 35-39) reduces the number of ganglion cells by half, from 6500 to 3200. Both ciliary and choroid populations are affected by approximately the same amount.2. Previous to cell death, preganglionic fibres form functional synapses on all ganglion cells, indicating that synapses form on cells which are destined to die.3. Shortly before the period of cell death, there is a failure of transmission in approximately half the cells. Some evidence suggests that transmission failure in at least some of the cells is of preganglionic origin.4. Cell death is nearly synchronous with the establishment of peripheral connexions by ganglion cells, at least with respect to the ciliary population which forms functional synapses with iris muscle. This implies that those cells which die do so because they have failed to form adequate peripheral connexions.5. It is suggested that many of the cells in which transmission has failed die, bringing transmission through the ganglion back to 100%. However, transmission failure appears to be a transitory phenomenon in other cells which survive and probably results from death of their preganglionic elements. Restoration of transmission would then be brought about by the formation of new or more effective synapses by surviving preganglionic fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373568"}
{"pmid": "4373571", "title": "Quantitative and graphic analysis of prosthetic treatment for \"nasalance\" in speech.", "content": "Quantitative and graphic analysis of prosthetic treatment for \"nasalance\" in speech.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373571"}
{"pmid": "4373569", "title": "The effects of caffeine on sodium transport, membrane potential, mechanical tension and ultrastructure in barnacle muscle fibres.", "content": "The effects of caffeine on sodium transport, membrane potential, mechanical tension and ultrastructure in barnacle muscle fibres. 1. The effects of graded concentrations of caffeine on the Na efflux were investigated. External application of 10 mM caffeine usually caused a biphasic response, viz. a fall, followed by a rise in the Na efflux. 1 and 5 mM caffeine usually caused stimulation. Only the stimulatory phase of this response depended on the presence of external Ca(2+).2. Internal application of 100 mM caffeine caused a small rise in the Na efflux, the magnitude of which was independent of external Ca(2+) and comparable to that obtained with external application of 1 mM caffeine. This action, however, could be greatly augmented by pre-treating the fibre with 5 x 10(-5)M ouabain.3. The rise in Na efflux caused by external application of 10 mM caffeine could be greatly augmented by pre-treating the fibre with 5 x 10(-5)M ouabain. The observed stimulatory response was biphasic, more so in the absence of external Ca(2+). Restoration of external Ca(2+) following the onset of the second stimulatory phase resulted in further rise of the Na efflux. Measurements of the Na efflux during treatment with graded concentrations of ouabain and 10 mM caffeine showed that the rate coefficient for Na efflux varied with the ouabain concentration in the range 10(-8)-10(-4)M. Measurements of the ouabain-insensitive Na efflux before and during treatment with 10 mM caffeine in bathing media containing varying concentrations of Ca, disclosed the existence of two Ca(2+)-thresholds, one in the 0-2.5 mM range and the other in the 12.5-15 mM range.4. Comparisons were made between the effects on the Na efflux of 10 mM caffeine followed by external acidification, and external acidification, followed by 10 mM caffeine. The magnitude of the response of the ouabain-insensitive Na efflux to external acidification before treatment with 10 mM caffeine was greater than that found when external acidification followed external application of the alkaloid. It also was considerably greater than that of the response to external application of 10 mM caffeine before external acidification.5. External application of 10 mM procaine prevented 10 mM caffeine from stimulating the Na efflux, and from inducing contractures. Internal application of 100 mM-EGTA reduced the response of the Na efflux to 10 mM caffeine, and also prevented the fibre from contracting. External application of 10(-4)M diphenylhydantoin reduced the response of the Na efflux to 10 mM caffeine but failed to prevent the development of contractures.6. Internal application of 0.05 M-cGMP, cAMP or its dibutyryl derivative caused a large rise in the Na efflux. The magnitude of the effects observed in ouabain-poisoned fibres was often greater than that in unpoisoned fibres. Internal application of 2.5 units/ml. phosphodiesterase beforehand failed to reduce the magnitude of the stimulatory response to injected cyclic nucleotides. Injected phosphodiesterase also failed to reduce the response of the Na efflux to 10 mM caffeine.7. External application of 10 mM caffeine to unpoisoned and ouabain-poisoned fibres caused a fall of approximately 10 mV in the membrane potential. In unpoisoned fibres this effect was transitory. The response of the membrane potential to internal application of graded concentrations of CaCl(2) was biphasic. When low concentrations of CaCl(2) were used the membrane potential underwent a small rise but when high concentrations were used the opposite was found. These results could not be repeated with graded concentrations of MgCl(2).8. The effects of graded concentrations of caffeine on tension development were also studied. Strong contractures were observed with caffeine concentrations as low as 4 mM, while peak tetanus tension was usually exceeded with 7-8 mM concentrations. The tension-external Ca(2+) curve was sigmoidal in shape.9. Electron microscopic studies showed that 10 mM caffeine in ASW caused little or no distension and disorganization of cisternal fine structure. Such structural changes, however, were far more pronounced in fibres suspended in Ca(2+)-free ASW and then treated with 10 mM caffeine in Ca(2+)-free ASW. Fibres soaked in Ca(2+)-free ASW had ruptured mitochondria and mitoplasts, whereas those additionally treated with 10 mM caffeine had relatively intact mitochondria.10. The main conclusions drawn from this work are: (i) that caffeine stimulates the ouabain-insensitive Na efflux (and inhibits the transport enzyme) by raising the internal free Ca(2+) concentration; (ii) that in the presence of inhibition of the transport enzyme, the magnitude of the stimulatory response to 10 mM caffeine depends not only on the external Ca(2+) concentration but mainly on the residual level of activity of the transport enzyme; (iii) that the Ca(2+)-sensitive and CO(2)-sensitive components of the ouabain-insensitive Na efflux, though not the same, may overlap at the level of the plasma membrane or share a common metabolic step away from the membrane; (iv) that cyclic nucleotides participate in the control of the magnitude of the ouabain-insensitive Na efflux, and that the phosphodiesterase system under the present experimental conditions does not seem to be involved in the mechanism underlying the stimulatory action of caffeine; (v) that the membrane potential changes caused by caffeine fail to explain the stimulatory response of the Na efflux, as well as contracture of these fibres; (vi) that the contractile machinery in these fibres is considerably more sensitive to caffeine than that in vertebrate muscle and the muscles of other arthropods, and (vii) that the Ca(2+) released by the sarcoplasmic reticulum which leads to a biphasic response of the Na efflux is the result of cisternal disorganization caused by caffeine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373569"}
{"pmid": "4373570", "title": "On the role of vasopressin and angiotensin in the development of irreversible haemorrhagic shock.", "content": "On the role of vasopressin and angiotensin in the development of irreversible haemorrhagic shock. 1. Long-lasting haemorrhagic hypotension (4.5 hr at 35 mmHg) leading to irreversible haemorrhagic shock, has been studied in normal dogs, in dogs treated with a bradykinin potentiating nonapeptide (BPP(9a)), which blocks the conversion of angiotensin I to angiotensin II, and in dogs with experimental chronic diabetes insipidus (DI dogs). BPP(9a) was given by I.V. injection before the start of bleeding (BPP pre-treated group), 45 min after blood pressure had reached 35 mmHg (BPP early treated group) or 2 hr after blood pressure had reached 35 mmHg (BPP late-treated group). After retransfusion of blood all dogs were allowed to recover and observed for a further period of 3 days.2. Untreated control dogs developed haemorrhagic shock with tachycardia, low cardiac output, low total peripheral conductance and low stroke volume. All died within 24 hr of retransfusion, with pathological lesions typical of irreversible haemorrhagic shock.3. BPP pre-treated dogs developed haemorrhagic shock with bradycardia (during early shock), high cardiac output, high peripheral vascular conductance and high stroke volume when compared with the untreated controls. All pre-treated animals survived the 3 day observation period. They were then killed and on post-mortem showed no signs of irreversible haemorrhagic shock.4. BPP early-treated animals behaved like controls before BPP, but like pre-treated animals after the drug. Only one out of eight died within the 3 day observation period.5. BPP late-treated dogs behaved like controls before BPP. They responded to the drug with a rise in cardiac output, peripheral vascular conductance and stroke volume, and with a fall in heart rate. These responses were, however, short-lived. Four out of these eight animals died within the 3 day observation period, with lesions of irreversible haemorrhagic shock.6. DI dogs developed haemorrhagic shock with tachycardia (like controls), but with high cardiac output and peripheral vascular conductance (like BPP pre-treated dogs). The stroke volume of DI dogs was intermediate between those of controls and pre-treated groups. All six dogs survived the 3 day observation period.7. BPP(9a) had no measurable effect on the course of endotoxic shock.8. It is suggested that the normally severe vasoconstriction of the mesenteric vascular bed, which is thought to be responsible for irreversible haemorrhagic shock, is absent or attenuated in the absence of vasopressin or angiotensin. The consequences of this on the development of irreversibility are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373570"}
{"pmid": "4373573", "title": "Wilms' tumor and neuroblastoma. Survey of a ten year experience.", "content": "Wilms' tumor and neuroblastoma. Survey of a ten year experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373573"}
{"pmid": "4373574", "title": "Relationship between Epstein-Barr virus-determined complement-fixing antigen and nuclear antigen detected by anticomplement fluorescence.", "content": "Relationship between Epstein-Barr virus-determined complement-fixing antigen and nuclear antigen detected by anticomplement fluorescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373574"}
{"pmid": "4373576", "title": "Interferon inhibition of autogenously induced virions (C particles) in synchronized L-929 cell cultures.", "content": "Interferon inhibition of autogenously induced virions (C particles) in synchronized L-929 cell cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373576"}
{"pmid": "4373575", "title": "A preliminary investigation into the role of immunity in modifying the blood- borne spread of chemically induced rat sarcomas.", "content": "A preliminary investigation into the role of immunity in modifying the blood- borne spread of chemically induced rat sarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373575"}
{"pmid": "4373577", "title": "A complement-fixation test for the bovine leukemia (C-type) virus.", "content": "A complement-fixation test for the bovine leukemia (C-type) virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373577"}
{"pmid": "4373578", "title": "Naturally occurring sarcoma virus of the BALB/cCr mouse.", "content": "Naturally occurring sarcoma virus of the BALB/cCr mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373578"}
{"pmid": "4373579", "title": "Inhibition of murine sarcoma development by deoxycorticosterone acetate.", "content": "Inhibition of murine sarcoma development by deoxycorticosterone acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373579"}
{"pmid": "4373580", "title": "Detection of mouse mammary tumor virus in cat kidney cells infected with purified B particles from RIII milk.", "content": "Detection of mouse mammary tumor virus in cat kidney cells infected with purified B particles from RIII milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373580"}
{"pmid": "4373581", "title": "Atypical C particles in adenocarcinomas induced by implantation of FUKU cells.", "content": "Atypical C particles in adenocarcinomas induced by implantation of FUKU cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373581"}
{"pmid": "4373582", "title": "Type-C virus particles in a feline angioma: a case report.", "content": "Type-C virus particles in a feline angioma: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373582"}
{"pmid": "4373584", "title": "Renal malignant histiocytoma.", "content": "Renal malignant histiocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373584"}
{"pmid": "4373583", "title": "Belated recognition of adrenocorticotropic hormone-producing tumors in post-adrenalectomized Cushing's syndrome.", "content": "Belated recognition of adrenocorticotropic hormone-producing tumors in post-adrenalectomized Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373583"}
{"pmid": "4373585", "title": "Serological indication of canine distemper and of infectious canine hepatitis in wolves (Canis lupus L.) in northern Canada.", "content": "Serological indication of canine distemper and of infectious canine hepatitis in wolves (Canis lupus L.) in northern Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373585"}
{"pmid": "4373586", "title": "Relationship of pulmonary particulates in English sparrows to gross air pollution.", "content": "Relationship of pulmonary particulates in English sparrows to gross air pollution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373586"}
{"pmid": "4373588", "title": "Vulvovaginitis in wildebeest caused by the virus of infectious bovine rhinotracheitis.", "content": "Vulvovaginitis in wildebeest caused by the virus of infectious bovine rhinotracheitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373588"}
{"pmid": "4373587", "title": "Survey of diseases in free-living California sea lions.", "content": "Survey of diseases in free-living California sea lions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373587"}
{"pmid": "4373591", "title": "Effect of several proteinase inhibitors on renin reaction.", "content": "Effect of several proteinase inhibitors on renin reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373591"}
{"pmid": "4373592", "title": "Clinical applications of synthetic angiotensin II analogue.", "content": "Clinical applications of synthetic angiotensin II analogue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373592"}
{"pmid": "4373593", "title": "Pressor responsiveness, hemodynamics and plasma renin activity in essential hypertension.", "content": "Pressor responsiveness, hemodynamics and plasma renin activity in essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373593"}
{"pmid": "4373594", "title": "Effects of angiotensin on catecholamine metabolism in rat.", "content": "Effects of angiotensin on catecholamine metabolism in rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373594"}
{"pmid": "4373595", "title": "Analysis of relationship between renin-angiotensin system and blood pressure in experimental hypertension induced by kidney extract.", "content": "Analysis of relationship between renin-angiotensin system and blood pressure in experimental hypertension induced by kidney extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373595"}
{"pmid": "4373596", "title": "The kidney factors in the production of acute hypertensive vascular lesions.", "content": "The kidney factors in the production of acute hypertensive vascular lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373596"}
{"pmid": "4373589", "title": "Successful medical adrenalectomy with amino-glutethimide. Role of altered drug metabolism.", "content": "Successful medical adrenalectomy with amino-glutethimide. Role of altered drug metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373589"}
{"pmid": "4373590", "title": "Management of hyperlipidemias.", "content": "Management of hyperlipidemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373590"}
{"pmid": "4373597", "title": "Effect of Ca on renin release in vitro and in vivo.", "content": "Effect of Ca on renin release in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373597"}
{"pmid": "4373599", "title": "Renin content in subcellular fractions of kidney extract of renovascular hypertensive rats.", "content": "Renin content in subcellular fractions of kidney extract of renovascular hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373599"}
{"pmid": "4373603", "title": "Detection of alpha-fetoprotein in mice infected with mouse hepatitis virus.", "content": "Detection of alpha-fetoprotein in mice infected with mouse hepatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373603"}
{"pmid": "4373604", "title": "Presence of glucosyl ceramide and lactosyl ceramide in human intracranial tumours.", "content": "Presence of glucosyl ceramide and lactosyl ceramide in human intracranial tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373604"}
{"pmid": "4373605", "title": "Properties of hemolytic streptococci grown in glucose-containing medium.", "content": "Properties of hemolytic streptococci grown in glucose-containing medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373605"}
{"pmid": "4373608", "title": "Separation of the contributions of voluntary and vibratory activation of motor units in man by cross-correlograms.", "content": "Separation of the contributions of voluntary and vibratory activation of motor units in man by cross-correlograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373608"}
{"pmid": "4373614", "title": "The ubiquitous effects of histamine phosphate on the atria of the albino mouse.", "content": "The ubiquitous effects of histamine phosphate on the atria of the albino mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373614"}
{"pmid": "4373616", "title": "Starch estimation in leaf tissue--a comparison of results using six methods.", "content": "Starch estimation in leaf tissue--a comparison of results using six methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373616"}
{"pmid": "4373615", "title": "Hexachlorophene-induced changes in central and peripheral myelinated axons of developing and adult rats.", "content": "Hexachlorophene-induced changes in central and peripheral myelinated axons of developing and adult rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373615"}
{"pmid": "4373618", "title": "The metabolic consequences of trauma.", "content": "The metabolic consequences of trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373618"}
{"pmid": "4373620", "title": "The valve action of intensity receptor.", "content": "The valve action of intensity receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373620"}
{"pmid": "4373619", "title": "Regulation of size and birefringence of the in vivo mitotic apparatus.", "content": "Regulation of size and birefringence of the in vivo mitotic apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373619"}
{"pmid": "4373617", "title": "The proximate chemical composition and the amino acid content of some Nigerian oil seeds.", "content": "The proximate chemical composition and the amino acid content of some Nigerian oil seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373617"}
{"pmid": "4373621", "title": "Localized oscillations in neural networks. I. General considerations with nonlinear differential equations.", "content": "Localized oscillations in neural networks. I. General considerations with nonlinear differential equations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373621"}
{"pmid": "4373622", "title": "Endoscopy of the thoracic duct (lymphoscopy) via the external jugular vein in dogs.", "content": "Endoscopy of the thoracic duct (lymphoscopy) via the external jugular vein in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373622"}
{"pmid": "4373623", "title": "A new technique for cannulating lymphatic vessels: experience in 150 extremities.", "content": "A new technique for cannulating lymphatic vessels: experience in 150 extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373623"}
{"pmid": "4373624", "title": "Lymphography without the aid of vital dyes.", "content": "Lymphography without the aid of vital dyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373624"}
{"pmid": "4373625", "title": "Agencies' perceptions of factors affecting home care referral.", "content": "Agencies' perceptions of factors affecting home care referral.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373625"}
{"pmid": "4373627", "title": "Hormones and sudden deafness.", "content": "Hormones and sudden deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373627"}
{"pmid": "4373628", "title": "Glomus tumors: diagnosis and treatment.", "content": "Glomus tumors: diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373628"}
{"pmid": "4373629", "title": "Electrical promontory testing in differential diagnosis of sensori-neural hearing impairment.", "content": "Electrical promontory testing in differential diagnosis of sensori-neural hearing impairment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373629"}
{"pmid": "4373630", "title": "Juvenile angiofibroma: a more rational therapeutic approach based upon clinical and experimental evidence.", "content": "Juvenile angiofibroma: a more rational therapeutic approach based upon clinical and experimental evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373630"}
{"pmid": "4373633", "title": "The prostaglandins: their significance in clinical practice.", "content": "The prostaglandins: their significance in clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373633"}
{"pmid": "4373635", "title": "Radioimmunoassay of polypeptide hormones and enzymes.", "content": "Radioimmunoassay of polypeptide hormones and enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373635"}
{"pmid": "4373637", "title": "Newer developments in the determination of cyclic AMP and other cyclic nucleotides, adenylate cyclase, and phosphodiesterase.", "content": "Newer developments in the determination of cyclic AMP and other cyclic nucleotides, adenylate cyclase, and phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373637"}
{"pmid": "4373636", "title": "The use of subzero temperatures in biochemistry: slow reactions.", "content": "The use of subzero temperatures in biochemistry: slow reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373636"}
{"pmid": "4373638", "title": "In vitro study of the influence of some factors important for any physicochemical characterization of loose connective tissue in the microcirculation.", "content": "In vitro study of the influence of some factors important for any physicochemical characterization of loose connective tissue in the microcirculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373638"}
{"pmid": "4373639", "title": "Peripheral neuropathy.", "content": "Peripheral neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373639"}
{"pmid": "4373640", "title": "Electron microscopic studies on various types of inclusions found in autopsy cases. PART 111. Observation on fine structure of cytomegalovirus in paraffin embedded tissue.", "content": "Electron microscopic studies on various types of inclusions found in autopsy cases. PART 111. Observation on fine structure of cytomegalovirus in paraffin embedded tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373640"}
{"pmid": "4373647", "title": "Models of the quaternary structure of collagenase.", "content": "Models of the quaternary structure of collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373647"}
{"pmid": "4373646", "title": "Physiology and genetics of carbamoylphosphate synthesis in Escherichia coli K12.", "content": "Physiology and genetics of carbamoylphosphate synthesis in Escherichia coli K12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373646"}
{"pmid": "4373648", "title": "Kinetic scheme and kinetic parameters of the exchange of ATP-32P-pyrophosphates, catalyzed by tryptophanyl-tRNA synthetase from beef pancreas.", "content": "Kinetic scheme and kinetic parameters of the exchange of ATP-32P-pyrophosphates, catalyzed by tryptophanyl-tRNA synthetase from beef pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373648"}
{"pmid": "4373651", "title": "Chloroquine inhibition of repair of DNA damage induced in mammalian cells by methyl methanesulfonate.", "content": "Chloroquine inhibition of repair of DNA damage induced in mammalian cells by methyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373651"}
{"pmid": "4373649", "title": "Amino acid esters of 2'-O-methyladenosing -peptide acceptors in the ribosome. The role of 2'-hydroxyl.", "content": "Amino acid esters of 2'-O-methyladenosing -peptide acceptors in the ribosome. The role of 2'-hydroxyl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373649"}
{"pmid": "4373650", "title": "Comparative studies of host-cell reactivation, colony forming ability and excision repair after UV irradiation of xeroderma pigmentosum, normal human and some other mammalian cells.", "content": "Comparative studies of host-cell reactivation, colony forming ability and excision repair after UV irradiation of xeroderma pigmentosum, normal human and some other mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373650"}
{"pmid": "4373652", "title": "Detection of somatic recombination and mutation in Drosophila. A method for testing genetic activity of chemical compounds.", "content": "Detection of somatic recombination and mutation in Drosophila. A method for testing genetic activity of chemical compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373652"}
{"pmid": "4373653", "title": "Effect of heterologous transplantation of H 4-II-E rat hepatoma cells into the cheek pouch of irradiated hamster.", "content": "Effect of heterologous transplantation of H 4-II-E rat hepatoma cells into the cheek pouch of irradiated hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373653"}
{"pmid": "4373654", "title": "Utilization of methadone hydrochloride for opiate addiction.", "content": "Utilization of methadone hydrochloride for opiate addiction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373654"}
{"pmid": "4373655", "title": "An SV40-induced initiation factor for protein synthesis concerned with the regulation of permissiveness.", "content": "An SV40-induced initiation factor for protein synthesis concerned with the regulation of permissiveness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373655"}
{"pmid": "4373656", "title": "Separation of parathyroid hormone and calcitonin-sensitive cells from non-responsive bone cells.", "content": "Separation of parathyroid hormone and calcitonin-sensitive cells from non-responsive bone cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373656"}
{"pmid": "4373657", "title": "Excitatory action of hypothalamic substance P on spinal motoneurones of newborn rats.", "content": "Excitatory action of hypothalamic substance P on spinal motoneurones of newborn rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373657"}
{"pmid": "4373658", "title": "Pseudotype formation between enveloped RNA and DNA viruses.", "content": "Pseudotype formation between enveloped RNA and DNA viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373658"}
{"pmid": "4373659", "title": "Effect of dexamethasone on herpes simplex virus type 2 infection in vitro.", "content": "Effect of dexamethasone on herpes simplex virus type 2 infection in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373659"}
{"pmid": "4373660", "title": "Increased susceptibility to virus oncogenesis of congenitally thymus-deprived nude mice.", "content": "Increased susceptibility to virus oncogenesis of congenitally thymus-deprived nude mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373660"}
{"pmid": "4373661", "title": "Inhibition of rat lymph node cell cytotoxicity by hepatoma-associated embryonic antigen.", "content": "Inhibition of rat lymph node cell cytotoxicity by hepatoma-associated embryonic antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373661"}
{"pmid": "4373662", "title": "[Site of transplantation and morphology of chemically induced gliomas in the rat].", "content": "[Site of transplantation and morphology of chemically induced gliomas in the rat].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373662"}
{"pmid": "4373663", "title": "Changes induced in rabbit plasma lipoproteins by polyunsaturated fat.", "content": "Changes induced in rabbit plasma lipoproteins by polyunsaturated fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373663"}
{"pmid": "4373669", "title": "Establishment of continuous cell lines from leukocytes culture of a hamadryas baboon with leukosis-reticulosis.", "content": "Establishment of continuous cell lines from leukocytes culture of a hamadryas baboon with leukosis-reticulosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373669"}
{"pmid": "4373670", "title": "Peripheral neuropathy in chronic renal failure.", "content": "Peripheral neuropathy in chronic renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373670"}
{"pmid": "4373678", "title": "Purified ovine growth hormone releasing factor: effects on growth hormone secretion and pituitary cyclic nucleotide accumulation.", "content": "Purified ovine growth hormone releasing factor: effects on growth hormone secretion and pituitary cyclic nucleotide accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373678"}
{"pmid": "4373679", "title": "Pituitary nuclear retention of dexamethasone and ACTH biosynthesis.", "content": "Pituitary nuclear retention of dexamethasone and ACTH biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373679"}
{"pmid": "4373680", "title": "Action of hemicholinium-3 on cholinergic nerve terminals after alteration of neuronal impulse flow.", "content": "Action of hemicholinium-3 on cholinergic nerve terminals after alteration of neuronal impulse flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373680"}
{"pmid": "4373682", "title": "Spontaneous skin potential responses during sleep: comparative studies in newborns and babies between 2 and 5 months of age.", "content": "Spontaneous skin potential responses during sleep: comparative studies in newborns and babies between 2 and 5 months of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373682"}
{"pmid": "4373684", "title": "Concurrent pulmonary tuberculosis and bronchogenic carcinoma. Experience in large municipal hospital.", "content": "Concurrent pulmonary tuberculosis and bronchogenic carcinoma. Experience in large municipal hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373684"}
{"pmid": "4373685", "title": "Letter: Hydrocyanic acid poisoning of cattle associated with sudax grass.", "content": "Letter: Hydrocyanic acid poisoning of cattle associated with sudax grass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373685"}
{"pmid": "4373686", "title": "Biologic behavior of primary ovarian malignancy.", "content": "Biologic behavior of primary ovarian malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373686"}
{"pmid": "4373688", "title": "Metabolic properties of mouse transplantable adenocarcinoma. III. Oxidative phosphorylation by tumor and normal submaxillary gland mitochondria.", "content": "Metabolic properties of mouse transplantable adenocarcinoma. III. Oxidative phosphorylation by tumor and normal submaxillary gland mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373688"}
{"pmid": "4373689", "title": "In vitro assay for human breast cancer hormone responsiveness. A study of 25 cases with clinical correlation.", "content": "In vitro assay for human breast cancer hormone responsiveness. A study of 25 cases with clinical correlation. The in vitro effects of cortisol, estradiol, progesterone, and testosterone on the uptake of tritiated thymidine into the tumor cells of 25 women with primary or metastatic breast cancer were studied and compared with the objective clinical  response to ablative endocrine surgery.  A correlation between the clinical results with endocrine therapy and the in vitro assay results obtained in 23 of the 25 patients.  8 patients who did not respond to clinical endocrine therapy did not respond in vitro.  A significant clinical response (p less than .05) to ablative endocrine surgery, lasting for at least 6 months, was observed in 9 of 15 patients whose tumors responded in vitro.  Precise determination of the predictive capacity of the assay will require a blind prospective evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373689"}
{"pmid": "4373690", "title": "Verruciform xanthoma. A clinical, light microscopic, and electron microscopic study of two cases.", "content": "Verruciform xanthoma. A clinical, light microscopic, and electron microscopic study of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373690"}
{"pmid": "4373691", "title": "Metastasis to the gingiva. Report of a case of metastasis from the breast and review of the literature.", "content": "Metastasis to the gingiva. Report of a case of metastasis from the breast and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373691"}
{"pmid": "4373697", "title": "A comparison of the bone seeking properties of short-chained 99mTc-Sn-polyphosphates.", "content": "A comparison of the bone seeking properties of short-chained 99mTc-Sn-polyphosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373697"}
{"pmid": "4373700", "title": "Renaturation of inactivated interferons by \"defensive reversible denaturation\".", "content": "Renaturation of inactivated interferons by \"defensive reversible denaturation\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373700"}
{"pmid": "4373701", "title": "Impact of adenoviruses in human disease.", "content": "Impact of adenoviruses in human disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373701"}
{"pmid": "4373702", "title": "Respiratory syncytial virus in infants and children.", "content": "Respiratory syncytial virus in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373702"}
{"pmid": "4373703", "title": "Parainfluenza virus infections.", "content": "Parainfluenza virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373703"}
{"pmid": "4373704", "title": "Sexually transmitted diseases.", "content": "Sexually transmitted diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373704"}
{"pmid": "4373705", "title": "Acute viral gastroenteritis.", "content": "Acute viral gastroenteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373705"}
{"pmid": "4373695", "title": "Enzymatic mechanisms in the chemotaxis of neutrophils.", "content": "Enzymatic mechanisms in the chemotaxis of neutrophils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373695"}
{"pmid": "4373706", "title": "Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemia.", "content": "Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemia. A new mechanism is described for the cellular esterification of cholesterol derived from extra-cellular lipoproteins. Incubation of monolayers of cultured fibroblasts from normal human subjects with low density lipoproteins led to a 30- to 40-fold increase in the rate of incorporation of either [(14)C]acetate or [(14)C]oleate into the fatty acid fraction of cholesteryl [(14)C]esters. This stimulation of cholesteryl ester formation by low density lipoproteins occurred despite the fact that endogenous synthesis of free cholesterol was completely suppressed by the lipoprotein. Thus, exogenous cholesterol contained in low density lipoproteins, rather than endogenously synthesized sterol, appeared to provide the cholesterol substrate for this cellular esterfication process. High density lipoproteins and the lipoprotein-deficient fraction of serum neither stimulated cholesteryl ester formation nor inhibited cholesterol synthesis. Both the low density lipoprotein-dependent increase in cholesterol esterification and decrease in free cholesterol synthesis required the interaction of the lipoprotein with its recently described cell surface receptor. Cells from homozygotes with familial hypercholesterolemia, which lack specific low density lipoprotein receptors, showed neither lipoprotein-dependent cholesterol esterification nor suppression of cholesterol synthesis. The reciprocal changes in free cholesterol synthesis and cholesteryl ester formation produced by low density lipoprotein-receptor interactions may play an important role in the regulation of the cholesterol content of mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373706"}
{"pmid": "4373707", "title": "Proton magnetic resonance spectra of Rhodospirillum rubrum cytochrome c2.", "content": "Proton magnetic resonance spectra of Rhodospirillum rubrum cytochrome c2. Nuclear magnetic resonance spectra of ferro- and ferricytochrome C(2) from the facultative photoheterotroph, Rhodospirillum rubrum, obtained with a 220-MHz spectrometer, are presented. Assignments to protons of various important structural groups in contact with or near the prosthetic heme group are given. These include (a) in the ferro-form, methyl, cbeta and cgamma protons of the extraplanar ligand residue, methionine 91, and methyl protons of the residue leucine 32; and (b) corresponding protons in the ferri-form with the addition of methyl protons from the condensation of a heme vinyl group with cysteine 17, a single proton from the condensation involving cysteine 14, and protons from the ring methyls. These resonances are compared with those corresponding to the same groups in horse heart cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373707"}
{"pmid": "4373708", "title": "Differential lectin agglutination of fetal, dividing-postnatal, and malignant hepatocytes.", "content": "Differential lectin agglutination of fetal, dividing-postnatal, and malignant hepatocytes. Numerous studies have reported the capacity of the lectin, concanavalin A, to agglutinate selected cell-types. The finding that cells transformed in culture, embryonic cells, and malignant cells are all agglutinated by this substance, may contribute to our understanding of the oncogenic process. The present study compared the response to concanavalin A of rat hepatocytes derived from livers of differing developmental and mitotic-status as well as those derived from malignant liver tumors (hepatomas). Fetal hepatocytes and hepatoma cells were highly susceptible to agglutination while hepatocytes from post-natal livers, whether dividing or quiescent, were not. Treatment with protease(s) did not make the interphase hepatocyte agglutinable. These data emphasize the importance of examining a wide variety of cells in attempting to understand the interaction of lectins on cell surfaces, and further, demonstrate the value of obtaining cells directly from tissue(s) during differing physiologic and pathologic states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373708"}
{"pmid": "4373709", "title": "Evolution of type C viral genes: I. Nucleic acid from baboon type C virus as a measure of divergence among primate species.", "content": "Evolution of type C viral genes: I. Nucleic acid from baboon type C virus as a measure of divergence among primate species. Hybridization studies with a [(3)H]DNA probe from an endogenous baboon type C virus were used to detect nucleic acid sequences of type C virus in primate cellular DNA. Sequences related to those of the baboon type C virus are found in all other Old World monkey species, higher apes, and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373709"}
{"pmid": "4373711", "title": "Characterization of binding components for progesterone and 5alpha-pregnane-3,20-dione in the hamster uterus.", "content": "Characterization of binding components for progesterone and 5alpha-pregnane-3,20-dione in the hamster uterus. In the hamster uterus, a specific progesterone (pregn-4-ene-3,20-dione) receptor has been identified in the cytosol fraction. In the present study, we examined hamster uterine cytosol for the possible existence of specific macromolecules that bind the progesterone metabolite, 5alpha-pregnane-3,20-dione. When cytosol was analyzed by density-gradient centrifugation with sucrose-glycerol gradients and by Scatchard plot analysis of [(3)H]5alpha-pregnane-3,20-dione binding data, there was no evidence of specific binding components for this metabolite. In vivo treatment of proestrous hamsters with unlabeled progesterone, 5alpha-pregnane-3,20-dione, or cortisol for 1 hr revealed that only progesterone caused the depletion of progesterone-receptor sites from the uterine cytosol fraction. Incubation of uterine strips which had been preloaded with two different concentrations of [(3)H]-progesterone demonstrated that progesterone was metabolized to 5alpha-pregnane-3,20-dione and to a greater extent to 3alpha-hydroxy-5alpha-pregnan-20-one. The accumulation of 5alpha-pregnane-3,20-dione during progesterone metabolism appeared to be related to the availability of nonspecifically bound hormone. These studies (i) strongly suggest there is no specific receptor system for 5alpha-pregnane-3,20-dione in the uterine cytosol fraction, (ii) confirm the existence of a specific progesterone receptor in uterine cytosol, and (iii) provide evidence that progesterone itself mediates the uterine progestational response via interaction with a specific receptor system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373711"}
{"pmid": "4373710", "title": "Regulation of herpesvirus macromolecular synthesis: nuclear retention of nontranslated viral RNA sequences.", "content": "Regulation of herpesvirus macromolecular synthesis: nuclear retention of nontranslated viral RNA sequences. We report two instances of selective accumulation of herpes simplex 1 RNA transcripts in different compartments of infected HEp-2 cells. In the first, transcripts derived from about 50% of the viral DNA accumulated in the nuclei of cells 8 hr after infection. However, only 40-42% of the DNA was represented in transcripts accumulating in both cytoplasm and polyribosomes. A more striking disparity in the distribution of transcripts between nuclei and cytoplasm occurred when viral infection was initiated and maintained for several hours in the absence of protein synthesis. RNA complementary to about 50% of the viral DNA accumulated in the nuclei, while transcripts derived from only about 10% of the DNA were detectable in the cytoplasm. The transcripts that were selectively transported in the presence of cycloheximide seem to be functional messenger RNA molecules, since they were found on polysomes immediately after cycloheximide reversal. In contrast, RNA retained in the nuclei during the period of cycloheximide treatment was not mobilized when protein synthesis subsequently resumed. The two instances of selective RNA transport observed during herpesvirus infection suggest that only viral transcripts competent to function in translation are exported from the nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373710"}
{"pmid": "4373712", "title": "Polyriboadenylate sequences at the 3'-termini of ribonucleic acid obtained from mammalian leukemia and sarcoma viruses.", "content": "Polyriboadenylate sequences at the 3'-termini of ribonucleic acid obtained from mammalian leukemia and sarcoma viruses. The location of poly(A) sequences in the RNA of mammalian RNA-tumor viruses was determined by enzymatic analyses. The 56-64S viral genomic RNAs, the 20-40S viral subunit RNAs, and the 4-5S poly(A) sequences excised from these viral RNAs were subjected to either hydrolysis with a 3'-OH specific exoribonuclease from Ehrlich ascites tumor cells or phosphorolysis from the 3'-termini with polynucleotide phosphorylase from Micrococcus luteus. Purified adenosine-labeled poly(A) fragments, excised from genomic viral RNAs by RNase A and T(1) digestion, were hydrolyzed with the 3'-OH specific exoribonuclease for various periods of time. Poly(U) filter binding studies of the residual poly(A) indicated that 97% of the poly(A) fragments were hydrolyzed. Adenosine-labeled genomic and subunit viral RNAs and excised poly(A) fragments were phosphorolyzed from their 3'-termini for various periods of time with polynucleotide phosphorylase. The degree of phosphorolysis was monitored by poly(U) filter binding studies, and CCl(3)COOH insolubility and solubility determinations. There was an initial preferential rate of phosphorolysis of the poly(A) sequences of genomic and subunit viral RNAs as compared to the total adenosine-labeled viral RNAs. The data from these two different enzymatic mechanisms of action indicated conclusively that the poly(A) sequences were located at the 3'-termini of genomic and subunit viral RNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373712"}
{"pmid": "4373713", "title": "Characterization of the end groups of RNA of Rous sarcoma virus.", "content": "Characterization of the end groups of RNA of Rous sarcoma virus. The 3' terminus of the 30-35S RNA of Rous sarcoma virus is adenosine. Its amount indicates an average molecular weight for that RNA of about 3 x 10(6). The 5' terminus of 30-35S RNA of Rous sarcoma virus was not di- or triphosphorylated, whether isolated by the standard procedure or from virus collected within 3 min of its release from the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373713"}
{"pmid": "4373715", "title": "Nuclear coupling of 33S and the nature of free radicals in irradiated crystals of cystine dihydrochloride: Part II, charged radicals.", "content": "Nuclear coupling of 33S and the nature of free radicals in irradiated crystals of cystine dihydrochloride: Part II, charged radicals. The (33)S hyperfine structure has been observed in negatively charged cystine molecule-radicals RCH(2)(SS)(-)CH(2)R. The coupling, found to be axially symmetric about the SS bond, proved the orbital of the unpaired electron to be an antibonding SS sigma(*) orbital with the spin density shared equally between 3p(sigma(*)) orbitals of the two sulfurs. The (33)S hyperfine structure could not be detected for a second radical produced by irradiation of the cystine hydrochloride crystal at 77 degrees K, but interpretation of the proton hyperfine structure and g tensor observed by others led to the conclusion that this radical is the positively charged cystine molecule RCH(2)S(+)SCH(2)R with the spin density concentrated in a 3p orbital of one S and perpendicular to the SS bond.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373715"}
{"pmid": "4373714", "title": "Physical and physiological evidence for two phase transitions in cytoplasmic membranes of animal cells.", "content": "Physical and physiological evidence for two phase transitions in cytoplasmic membranes of animal cells. Electron spin resonance analysis of suspensions of animal cell plasma membranes consistently reveals four characteristic temperatures for lateral phase separations in the membrane lipids. Similar analysis of an aqueous dispersion of lipids extracted from these membranes reveals only two characteristic temperatures, indicating that some aspect of lipid organization in membranes is destroyed by the extraction procedure. The characteristic temperatures for surface membranes from two different species of homeothermic animals were nearly identical and were approximately 37 degrees , 31 degrees , 21 degrees , and 15 degrees . A treatment of the physical data revealed that these temperatures could identify independent phase transitions for two hydrocarbon compartments of approximately equal size with lower and upper characteristic temperatures of 21 degrees and 37 degrees , and of 15 degrees and 31 degrees . The analysis of the effects of temperature on a number of physiological parameters indicates that 21 degrees and 37 degrees are likely to define the boundaries for lateral phase separations in the inner monolayer and 15 degrees and 31 degrees the boundaries for lateral phase separations in the outer monolayer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373714"}
{"pmid": "4373716", "title": "Gap junction formation between reaggregated Novikoff hepatoma cells.", "content": "Gap junction formation between reaggregated Novikoff hepatoma cells. We have combined freeze-fracture and electrophysiological methods in a study of gap junction formation between reaggregated Novikoff hepatoma cells. Cell clumps are dissociated with EDTA, and the resulting single cells are allowed to reaggregate (5-180 min) in loose pellets in the presence of calcium at 37 degrees . The earliest electron microscopic evidence for the genesis of new junctions is the appearance of flattened regions of the plasma membrane with a relative paucity of small intramembranous particles. These regions contain instead loosely organized groupings of 9- to 11-nm intramembranous particles, which are seen on the A face of the fractured plasma membrane, while corresponding pits occur on the membrane B face. We have termed the specialized membrane regions \"formation plaques.\" They are seen as early as 5 min after reaggregation and are quite numerous by 30 min. Larger plaques are observed at later times. Plaques seen at 30 min are consistently matched with other plaques on apposed cells, although the extracellular space separating these structures still exceeds 10 nm. By 60 min, some matched plaques display a reduced extracellular space, resembling that of normal gap junctions. Between 30 and 60 min, aggregates of closely packed particles on A faces and hexagonally arranged pits on B faces frequently appear in the formation plaques. The aggregates, which are indistinguishable from small gap junctions, appear to enlarge over the subsequent 2-hr period as the number of unaggregated 9- to 11-nm particles declines. Microelectrode studies demonstrate progressive increases in the percent of interfaces containing lowresistance junctions and in the degree of elctrical coupling in preparations incubated up to 2 hr. Coupling is first detected at about the same time as particle aggregates (or formation plaques with reduced extracellular spaces), and increases as aggregate sizes increase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373716"}
{"pmid": "4373717", "title": "Structure and molecular weight of the 60-70S RNA and the 30-40S RNA of the Rous sarcoma virus.", "content": "Structure and molecular weight of the 60-70S RNA and the 30-40S RNA of the Rous sarcoma virus. The structure and molecular weight of the 60-70S RNA complex and the 30-40S RNA species of Rous sarcoma virus were analyzed in an electron microscope after treatment of the RNAs with the bacteriophage T4 gene-32 protein to stretch out the RNA strands. Although all RNA preparations treated with gene-32 protein showed considerable heterogeneity in length, a significant fraction of the RNA retained its original sedimentation coefficient after treatment to allow the following conclusions to be made: The 30-40S RNA was confirmed to be a linear polynucleotide with a molecular weight of about 3 x 10(6). The 60-70S RNA exhibited a network structure with a molecular weight predominantly of about 6 x 10(6). Therefore, the subunit hypothesis for the 60-70S RNA is confirmed. A model for the structure and molecular weight of the 60-70S RNA postulates that the complex consists of two 30-40S RNA subunits held together at many points. This model elucidates the biological observation that the infectivity of RNA tumor viruses is proportional to the amount of 30-40S RNA in a virus preparation and not to the amount of 60-70S RNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373717"}
{"pmid": "4373718", "title": "Intramolecular hydrogen bonding in flavin adenine dinucleotide.", "content": "Intramolecular hydrogen bonding in flavin adenine dinucleotide. Data obtained by means of proton magnetic resonance spectroscopy indicate that specific association of FMN occurs with AMP in aqueous solution, because much weaker interaction is observed with FMN of either GMP or CMP. A comparison of FAD with a 1:1 mixture of FMN and AMP suggests that the flavin is involved in an intramolecular hydrogen bonding with the adenine moiety of FAD. The temperature dependence of chemical shifts would seem to indicate that the pyrophosphate linkage acts to reinforce stacking interactions as well as hydrogen bonding in the coenzyme. The linkage also limits the number of cyclic hydrogen bonding configurations, and a model is proposed to describe a fraction of unstacked FAD in aqueous solution.A parallel study was made of NAD(+) and its analogues; in contrast to FAD, no clear evidence of cyclic hydrogen bonding was obtained with the pyridine coenzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373718"}
{"pmid": "4373719", "title": "Purification and properties of rat liver microsomal stearyl coenzyme A desaturase.", "content": "Purification and properties of rat liver microsomal stearyl coenzyme A desaturase. The terminal enzyme of the NADH-dependent stearyl coenzyme A desaturase system has been isolated from rat liver microsomes. This desaturase is a single polypeptide of 53,000 daltons containing 62% nonpolar amino-acid residues and one atom of non-heme iron. The purified protein forms high molecular weight aggregates that can be dispersed by detergent procedures. Desaturase activity requires NADH, stearyl coenzyme A, oxygen, lipid, and the three enzymes, cytochorme b(5) reductase (EC 1.6.2.2), cytochrome b(5), and desaturase. Cytochrome b(5) is the direct electron donor to the desaturase, which appears to utilize the iron in the oxidation-reduction sequence during desaturation of stearyl coenzyme A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373719"}
{"pmid": "4373720", "title": "Behavior of three types of ribovirus-like particles in segregating hamster times mouse somatic hybrids.", "content": "Behavior of three types of ribovirus-like particles in segregating hamster times mouse somatic hybrids. An electron microscopic study of somatic hybrids resulting from a cross between hamster melanoma cells harboring R-type particles and mouse fibroblasts harboring intracisternal A-type and (mostly) immature C-type particles was performed. The major findings are: (a) hybrid cells that retain a large fraction of both hamster and mouse chromosomes produce all three types of particles; (b) the loss of mouse chromosomes is followed by that of intracisternal A- and C-type particles; (c) the continued production of A- and C-type particles is dependent on the retention of different mouse chromosomes; (d) the mixed intracellular population of R- and A-particles comprises a small number of complex structures in which the two types of virions are enclosed within a common envelope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373720"}
{"pmid": "4373721", "title": "Adenylate cyclase from Brevibacterium liquefaciens. III. In situ regulation of adenylate cyclase by pyruvate.", "content": "Adenylate cyclase from Brevibacterium liquefaciens. III. In situ regulation of adenylate cyclase by pyruvate. In the presence of DL-alanine intracellular cyclic AMP in nonproliferating cells of Brevibacterium liquefaciens increased rapidly to the maximum level of approximately 180 muM, and extracellular cyclic AMP increased to 100 muM within 4 hr at 25 degrees . Adenylate cyclase (EC 4.6.1.1) induction was not observed during this incubation. The concentration of pyruvate in the total culture increased concomitantly with that of cyclic AMP and reached approximately 20 mM after 4 hr of incubation. Since the activity of cyclic nucleotide phosphodiesterase is extremely low in this bacterium, the accumulation of cyclic AMP with DL-alanine appeared to be due to the activation of adenylate cyclase by pyruvate. D-alanine was more effective than L-alanine in producing pyruvate, and a high activity of D-alanine oxidation was detected in the cell lysate of B. liquefaciens.Thus, adenylate cyclase in this bacterium appeared to be regulated in vivo by pyruvate which was formed, in this case, predominantly from D-alanine through the action of D-aminoacid oxidase (EC 1.4.3.3). Pyruvate, added extracellularly, also caused a rapid accumulation of intracellular cyclic AMP. Glucose did not change the level of cyclic AMP significantly. It also did not affect the intracellular accumulation of cyclic AMP with DL-alanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373721"}
{"pmid": "4373722", "title": "Participation of N1-oxide derivatives of adenine nucleotides in the phosphotransferase activity of liver mitochondria.", "content": "Participation of N1-oxide derivatives of adenine nucleotides in the phosphotransferase activity of liver mitochondria. The modified adenine nucleotides ATP-NO, ADP-NO, and AMP-NO were tested as potential substrates and/or inhibitors of mitochondrial phosphotransferases. ADP-NO is not recognized by the translocase system located in the inner mitochondrial membrane; however, it is rapidly phosphorylated to ATP-NO in the outer compartment of mitochondria, by way of the nucleosidediphosphate kinase (EC 2.7.4.6) reaction, provided there is sufficient ATP in the mitochondria. AMP-NO is not phosphorylated by liver mitochondria to the corresponding nucleoside diphosphate; it cannot serve as substrate for adenylate kinase (EC 2.7.4.3). ATP-NO and ADP-NO, however, are substrates of this enzyme. The apparent equilibrium constant for the reaction, ADP-NO + ADP right harpoon over left harpoon ATP-NO + AMP, of 0.908 at pH 7.4 and 5 mM Mg(2+) is significantly higher than that of the reaction with natural nucleotides. Although adenosine N(1)-oxide is easily phosphorylated to AMP-NO by adenosine kinase [Schnebli et al. (1967) J. Biol. Chem. 242, 1997-2004], the formation of corresponding nucleoside triphosphate in vivo seems also to be limited by adenylate kinase; adenosine N(1)-oxide cannot replace adenosine in restoring the normal ATP level in ethionine-treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373722"}
{"pmid": "4373723", "title": "Effect of a fibroblast growth factor, insulin, dexamethasone, and serum on the morphology of BALB/c 3T3 cells.", "content": "Effect of a fibroblast growth factor, insulin, dexamethasone, and serum on the morphology of BALB/c 3T3 cells. The effects of serum, fibroblast growth factor, dexamethasone, and insulin on the morphology of two lines of BALB/c 3T3 cells are described and illustrated. Fibroblast growth factor, a polypeptide purified from bovine brain and pituitary glands, stimulates DNA synthesis and cell division in both sparse and confluent cultures of quiescent 3T3 cells. When cells are grown in the presence of the factor, they go through one or two cycles of division and their morphology differs from that of cells either growing in 10% serum or maintained in a quiescent state in low serum; they appear rounded with long processes and show no sign of contact inhibition. When dexamethasone is present with the growth factor, the cells grow to a high density and are not contact-inhibited; they have the appearance of transformed cells. Addition of insulin or dibutyryl cyclic AMP to the cells results in a morphology similar to that of cells growing in the presence of serum. Addition of growth factor or growth factor plus dexamethasone to cells that have reached confluency in 10% serum and that are clearly contact-inhibited results in the resumption of growth. The final cell density reached is similar to that of cells growing in the presence of 30% serum with daily fluid changes. No contact inhibition is observed in either of these situations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373723"}
{"pmid": "4373724", "title": "Glycophorin in lipid bilayers.", "content": "Glycophorin in lipid bilayers. Glycophorin, the major glycoprotein of human erythrocytes, has been isolated and reincorporated into lipid vesicles. Freeze-fracture electron microscopy shows the reincorporated glycophorin to occur as small particles in vesicle fracture faces while the etch faces are smooth. The glycoprotein has a tendency to cluster into groups of several particles. Evidence is presented that, although lipids in immediate contact with glycopherin are likely somewhat immobilized, the entire lipid-protein complex has a tendency to occupy fluid regions of the bilayer. Reincorporated glycophorin assumes its proposed conformation in the intact erythrocyte in so far as it penetrates the hydrophobic membrane interior while its N-terminal end with attached carbohydrate residues is exposed to the aqueous compartment and is available as a specific recognition site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373724"}
{"pmid": "4373725", "title": "Latent DNA of Epstein-Barr virus: separation from high-molecular-weight cell DNA in a neutral glycerol gradient.", "content": "Latent DNA of Epstein-Barr virus: separation from high-molecular-weight cell DNA in a neutral glycerol gradient. Epstein-Barr virus DNA in virus non-productive cells was separated from high-molecular-weight cell DNA by sedimentation through a neutral glycerol gradient after gentle lysis of cells by Pronase and Sarkosyl. The isolated Epstein-Barr virus DNA had a density of 1.716-1.717 g/cm(3) in CsCl equilibrium centrifugation, which is very close to the virus DNA density of 1.718 g/cm(3). The results indicated that the majority of Epstein-Barr virus DNA in virus nonproductive cells is not covalently integrated into high-molecular-weight cell DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373725"}
{"pmid": "4373726", "title": "Coexistence of several putative neurotransmitters in single identified neurons of Aplysia.", "content": "Coexistence of several putative neurotransmitters in single identified neurons of Aplysia. By sensitive enzymatic micromethods several putative neurotransmitters were measured in four identifiable neurons of Aplysia californica (R-2, R-14, L-11, and C-1). Serotonin was found in all of these neurons, and octopamine in all but C-1. Acetylcholine has been previously reported to be present in R-2 and L-11. The catecholamines, norepinephrine and dopamine, were not detected in the four cells examined. The possible biological consequence of the presence of several putative transmitters in single identifiable neurons is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373726"}
{"pmid": "4373727", "title": "Competitive inhibition of beef heart cyclic AMP phosphodiesterase by cytokinins and related compounds.", "content": "Competitive inhibition of beef heart cyclic AMP phosphodiesterase by cytokinins and related compounds. Two cytokinins and four related analogs, none of which is a cyclic ribonucleotide, have been shown to act as competitive inhibitors of the high K(m) cyclic-AMP phosphodiesterase (3':5'-cyclic-AMP 5'-nucleotidohydrolase, EC 3.1.4.17) activity from beef heart. Weak inhibition of the low K(m) cyclic AMP phosphodiesterase activity was also observed, suggesting a possible mechanism for regulation of intracellular cyclic AMP levels by the exogenously added compounds. In addition to the kinetic data, obtained on the six inhibitors in four different heterocyclic series, 15 other cytokinins and related compounds have been shown to inhibit the high K(m) cyclic AMP phosphodiesterase activity at single concentrations of substrate and inhibitor. Heterocycles such as adenosine and 7-amino-3-methylpyrazolo[4,3-d]pyrimidine, which lack the N-substituent, were inactive as cyclic AMP phosphodiesterase inhibitors. The observed inhibition of cyclic AMP phophodiesterase supports prior observations which implicate exogenously added cytokinins in cyclic AMP metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373727"}
{"pmid": "4373728", "title": "Direct evidence for the presence of Epstein-Barr virus DNA and nuclear antigen in malignant epithelial cells from patients with poorly differentiated carcinoma of the nasopharynx.", "content": "Direct evidence for the presence of Epstein-Barr virus DNA and nuclear antigen in malignant epithelial cells from patients with poorly differentiated carcinoma of the nasopharynx. A well-differentiated squamous cell carcinoma and three poorly differentiated carcinomas of the nasopharynx were analyzed for the presence of Epstein-Barr virus DNA by hybridization with radioactive complementary RNA. The well-differentiated carcinoma contained no detectable Epstein-Barr virus DNA, whereas the three anaplastic carcinomas contained 41, 16, and 14 viral genome equivalents per cell. The anaplastic carcinomas were heavily infiltrated with lymphocytes and other non-neoplastic cells. All four tumors were successfully passaged in nude (thymusless) mice. Mouse cell admixture in the heterotransplanted tumors was estimated by analysis of glucose-6-phosphate dehydrogenase (EC 1.1.1.49) and varied between 25% and 80%. After two passages in nude mice, the carcinoma that was negative for Epstein-Barr virus DNA remained negative, while the three anaplastic carcinomas retained their viral DNA. After correction for mouse cell admixture, the latter tumors were found to contain about 80, 55, and 160 Epstein-Barr virus genome equivalents per human cell. The virus-determined nuclear antigen was localized in the large carcinoma cell clusters in all three mouse-passaged tumors positive for the viral DNA, but other virus-determined antigens were not detected, indicating the absence of virus induction. In contrast to the original tumor biopsies, the nude-mouse-passaged tumors showed virtually no lymphocytic infiltration. It is concluded that the Epstein-Barr virus DNA found in biopsies of human nasopharyngeal carcinomas is localized in the neoplastic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373728"}
{"pmid": "4373729", "title": "Isolation of a viral polypeptide associated with poliovirus RNA polymerase.", "content": "Isolation of a viral polypeptide associated with poliovirus RNA polymerase. Poliovirus-infected HeLa cells were labeled with radioactive methionine or phenylalanine and subjected to a new purification procedure for the viral induced RNA polymerase activity. Detergent-solubilized polymerase activity was purified by precipitation with 2 M LiCl and sedimentation through sucrose gradients. Approximately 0.001% of the incorporated amino acid radio-activity sediments with the peak of polymerase activity. Gradient fractions comprising the polymerase activity peak were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and found to contain predominantly one virus-specific polypeptide. Polyacrylamide gel electrophoresis also reveals that this purified polypeptide migrates with a 58,000 molecular weight noncapsid polio-virus polypeptide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373729"}
{"pmid": "4373730", "title": "Plasminogen activator production accompanies loss of anchorage regulation in transformation of primary rat embryo cells by simian virus 40.", "content": "Plasminogen activator production accompanies loss of anchorage regulation in transformation of primary rat embryo cells by simian virus 40. We have isolated several lines of rat embryo cells transformed by simian virus 40. All these lines are fully transformed with regard to saturation density and serum sensitivity, but they differ greatly in their anchorage dependence, as assayed by efficiency of plating in methyl cellulose suspension. This set of lines reveals a consistent relation of plasminogen activator production to plating efficiency in methyl cellulose. T-antigen-positive transformed lines that synthesize activator grow in methyl cellulose suspension, while T-antigen-positive transformed lines that do not synthesize activator fail to form colonies in suspension. Normal rat embryo cells produce very little plasminogen activator and do not grow in methyl cellulose. Sera that permit high levels of plasmin formation and activity support growth in semi-solid medium better than sera whose plasminogen is activated poorly and/or sera that contain inhibitors to plasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373730"}
{"pmid": "4373731", "title": "Focal erythrocyte membrane perturbations caused by nitroxide lipid analogues.", "content": "Focal erythrocyte membrane perturbations caused by nitroxide lipid analogues. Three classes of lipoidal nitroxide spin probes reversibly perturb erythrocyte membranes at low concentrations (10(-10)-10(-5) M). This is manifest in (a) decreased osmotic fragility and (b) alterations of surface topology. At bulk phase nitroxide concentrations providing maximal osmotic stabilization, the erythrocytes exhibit a classic echinocyte morphology. At nitroxide concentrations very slightly higher than those yielding minimal osmotic fragility (10(-5)-10(-4) M), the cellus undergo a sphering reaction and lyse. The morphologic sequence seen in intact cells is not observed in erythrocyte ghosts. We suggest that the spin probes initially concentrate in focal domains, which expand into echinocytic protrusions primarily due to localized weakening of membrane cohesion. We propose that cell lysis involves an irreversible breakdown in membrane domain structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373731"}
{"pmid": "4373732", "title": "Viable deletion mutants of simian virus 40: selective isolation by means of a restriction endonuclease from Hemophilus parainfluenzae.", "content": "Viable deletion mutants of simian virus 40: selective isolation by means of a restriction endonuclease from Hemophilus parainfluenzae. Resistance of simian virus 40 (SV40) DNA to cleavage by Hemophilus parainfluenzae II (HpaII) restriction endonuclease has been used as a positive, in vitro selection for mutants lacking the one HpaII endonuclease-cleavage site of wild-type SV40 DNA. Each of 10 viable mutants isolated by this procedure multiplies significantly more slowly than wild-type virus and contains a small deletion (80 to 190 base pairs in size) of the region of the genome that includes the HpaII endonuclease-recognition sequence. These well-defined mutants, having a selective disadvantage for growth, would not have been readily obtained by conventional methods used to screen for viral mutants. Therefore, in certain circumstances, restriction endonucleases are effective reagents for the selection of new classes of mutants. Because these small deletions can be visualized in heteroduplexes, these mutants provide internal markers for mapping other alterations or features of the simian virus 40 genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373732"}
{"pmid": "4373733", "title": "Initiator RNA in discontinuous polyoma DNA synthesis.", "content": "Initiator RNA in discontinuous polyoma DNA synthesis. During replication of polyoma DNA in isolated nuclei, RNA was found attached to the 5' ends of growing progeny strands. This RNA starts with either ATP or GTP and can be labeled at its 5' end with (32)P from beta-labeled nucleotides. Digestion of progeny strands with pancreatic DNase released (32)P-labeled RNA that, on gel electrophoresis, gave a distinct peak in the position expected for a decanucleotide. We believe that this short RNA is involved in the initiation of the discontinuous synthesis of DNA and propose the name \"initiator RNA\" for it. The covalent linkage of initiator RNA to 5' ends of growing DNA chains was substantiated by the finding that (32)P was transferred to ribonucleotides by alkaline hydrolysis of purified initiator RNA obtained by DNase digestion of polyoma progeny strands synthesized from [alpha-(32)P]dTTP. While initiator RNA was quite homogeneous in size, it had no unique base sequence since digestion with pancreatic RNase of initiator RNA labeled at its 5' end with (32)P released a variety of different [(32)P]oligonucleotides. The switch from RNA to DNA synthesis during strand elongation may thus depend on the size of initiator RNA rather than on a specific base sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373733"}
{"pmid": "4373734", "title": "Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor Tu.", "content": "Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor Tu. Kirromycin, a new inhibitor of protein synthesis, is shown to interfere with the peptide transfer reaction by acting on elongation factor Tu (EF-Tu). All the reactions associated with this elongation factor are affected. Formation of the EF-Tu.GTP complex is strongly stimulated. Peptide bond formation is prevented only when Phe-tRNA(Phe) is bound enzymatically to ribosomes, presumably because GTP hydrolysis associated with enzymatic binding of Phe-tRNA(Phe) is not followed by release of EF-Tu.GDP from the ribosome. This antibiotic also enables EF-Tu to catalyze the binding of Phe-tRNA(Phe) to the poly(U).ribosome complex even in the absence of GTP. EF-Tu activity in the GTPase reaction is dramatically affected by kirromycin: GTP hydrolysis, which normally requires ribosomes and aminoacyl-tRNA, takes place with the elongation factor alone. This GTPase shows the same K(m) for GTP as the one dependent on Phe-tRNA(Phe) and ribosomes in the absence of the antibiotic. Ribosomes and Phe-tRNA(Phe), but not tRNA(Phe) or Ac-Phe-tRNA(Phe), stimulate the kirromycin-induced EF-Tu GTPase. These results indicate that the catalytic center of EF-Tu GTPase that is dependent upon aminoacyl-tRNA and ribosomes is primarily located on the elongation factor. In conclusion, kirromycin can substitute for GTP, aminoacyl-tRNA, or ribosomes in various reactions involving EF-Tu, apparently by affecting the allosteric controls between the sites on the EF-Tu molecule interacting with these components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373734"}
{"pmid": "4373735", "title": "Cyclic nucleotides and growth control in cultured mouse cells: correlation of changes in intracellular 3':5' cGMP concentration with a specific phase of the cell cycle.", "content": "Cyclic nucleotides and growth control in cultured mouse cells: correlation of changes in intracellular 3':5' cGMP concentration with a specific phase of the cell cycle. The commencement of cell growth following serum addition to quiescent cultures of mouse fibroblasts is preceded by transient changes in intracellular concentrations of cAMP and cGMP. By artificial depletion of the culture medium for different nutrients, cell growth can be reversibly arrested in various phases of the cell cycle. Here it is shown that the major cGMP increases are only observed when cultures which are arrested in the G(0) phase are stimulated to grow or when synchronized growing cells pass through the G(1) phase. In addition to its concomitant decrease, cAMP exhibits rhythmic changes during the cell cycle. This suggests that the increase in cGMP could act as a specific signal for movement of cells out of the G(0) or G(1) phase of the cell cycle by activating the pleiotypic and mitogenic program of the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373735"}
{"pmid": "4373736", "title": "Demonstration of a genetic factor influencing spontaneous release of a xenotropic virus of mouse cells.", "content": "Demonstration of a genetic factor influencing spontaneous release of a xenotropic virus of mouse cells. There is increasing evidence that mouse cells of different strains contain different numbers and biologic classes of naturally-integrated type-C RNA viruses. The present studies have examined the cellular regulation of one class of virus, xenotropic in host range, which is common to mice of NIH Swiss and NZB strains. This virus is spontaneously released at high level by NZB embryo cells but its production by NIH Swiss embryo cells is below detectable levels. Quantitative analysis of the chronic level of virus release by embryo cell lines established in tissue culture from genetic crosses of NIH and NZB strains has demonstrated the existence of a partially dominant gene influencing virus release. Evidence is presented indicating that this gene may act to provide a factor necessary for expression of a specific class of endogenous virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373736"}
{"pmid": "4373737", "title": "Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the chemical mutagen ethyl methanesulfonate.", "content": "Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the chemical mutagen ethyl methanesulfonate. An unscheduled DNA synthesis has been clearly demonstrated in meiotic and postmeiotic germ cell stages of the male mouse after in vivo treatment with a 250 mg/kg dose of ethyl methanesulfonate. The germ cell stages showing unscheduled DNA synthesis range from early to middle meiotic prophase stages through early to middle spermatid stages. The initiation of this synthesis, taken to be repair of chemically damaged DNA in these germ cells, is rapid, beginning within 1 hour after the injection of ethyl methanesulfonate. Unscheduled DNA synthesis has not been detected in the most mature germ cell stages, which give rise to dominant lethal mutations, nor does it occur in germ cell stages where protamine has replaced the chromosomal histones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373737"}
{"pmid": "4373738", "title": "A quantal analysis of the synaptic depression underlying habituation of the gill-withdrawal reflex in Aplysia.", "content": "A quantal analysis of the synaptic depression underlying habituation of the gill-withdrawal reflex in Aplysia. Habituation, one of the simplest behavioral paradigms for studying memory, has recently been examined on the cellular level in the gill-withdrawal reflex in the mollusc Aplysia and in the escape response in cray-fish. In both cases short-term habituation involved a decrease in excitatory synaptic transmission at the synapses between the sensory neurons and their central target cells. To analyze the mechanisms of the synaptic depression in Aplysia, we applied a quantal analysis to synaptic transmission between the sensory and motor neurons of the gill-withdrawal reflex. Our results indicate that short-term habituation results from a presynaptic mechanism: a decrease in the number of transmitter quanta released per impulse. The sensitivity of the postsynaptic receptor remains unaltered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373738"}
{"pmid": "4373741", "title": "Neurosurgical aspects of recurrent meningitis.", "content": "Neurosurgical aspects of recurrent meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373741"}
{"pmid": "4373740", "title": "Active transport of calcium in inverted membrane vesicles of Escherichia coli.", "content": "Active transport of calcium in inverted membrane vesicles of Escherichia coli. Accumulation of (45)Ca(++) was found to occur in membrane vesicles of E. coli prepared by lysis with a French pressure cell. The uptake occurs by active transport, requiring an energy source. Substrates of the electron transport chain, including D-lactate, reduced phenazine methosulfate, and NADH, stimulated accumulation, but this effect was blocked by the addition of cyanide. ATP could also stimulate accumulation, and this effect was blocked by dicyclohexylcarbodiimide. Uncouplers of oxidative phosphorylation inhibited the accumulation driven by either type of energy source. Accumulation of calcium is rapid, reaching the steady-state plateau within 1 min. Addition of phosphate to the assay buffer results in a prolongation of the reaction, allowing for the time-dependent accumulation of calcium for as long as 30 min. Vesicles prepared by lysis with a French pressure cell exhibit almost no ability to accumulate proline, while vesicles prepared by the method of Kaback transport proline but exhibit little energy-dependent transport of calcium. It is suggested that the accumulation of calcium in these vesicles, which are believed to be inverted, reflects a system that in vivo is responsible for the active extrusion of calcium from the cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373740"}
{"pmid": "4373739", "title": "Expression of murine leukemia virus structural antigens on the surface of chemically induced murine sarcomas.", "content": "Expression of murine leukemia virus structural antigens on the surface of chemically induced murine sarcomas. Cultured cells of different chemically-induced C57BL/6N murine sarcomas produced variable amounts of infectious murine leukemia virus (MuLV) and contained proportional amounts of MuLV structural components as determined by radioimmunoassay. Monospecific antisera directed against the major MuLV glycoprotein (gp71), the major internal antigen (p30), and the ribonucleoprotein (p10) were capable of mediating tumor cell lysis in the presence of complement, suggesting that these viral structural components were localized at least in part to the cell surface. Membrane immunofluorescence studies with MuLV p30 antiserum confirmed surface localization. Addition of MuLV p30 polypeptide to normal cells and tumor cells enhanced the cytotoxicity of MuLV p30 antiserum. Studies are presented which suggest that the presence of MuLV structural components on cell surfaces can be independent of virus production and cellular transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373739"}
{"pmid": "4373746", "title": "Encephalomyocarditis (EMC) virus infection of the femoral artery of newborn mice.", "content": "Encephalomyocarditis (EMC) virus infection of the femoral artery of newborn mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373746"}
{"pmid": "4373745", "title": "Effect of acute cardiac overload on intramyocardial cyclic 3',5'-AMP: relation to prostaglandin synthesis.", "content": "Effect of acute cardiac overload on intramyocardial cyclic 3',5'-AMP: relation to prostaglandin synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373745"}
{"pmid": "4373747", "title": "Studies on the characterization of pure submaxillary gland renin.", "content": "Studies on the characterization of pure submaxillary gland renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373747"}
{"pmid": "4373748", "title": "Effect of dibutyryl cyclic AMP and serum deprivation on the membranes of transformed mouse fibroblasts. A freeze fracture study.", "content": "Effect of dibutyryl cyclic AMP and serum deprivation on the membranes of transformed mouse fibroblasts. A freeze fracture study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373748"}
{"pmid": "4373749", "title": "Different sensitivities of type 1 and type 2 Herpes simplex virus to sodium p-chloromercuribenzoate and chlorhexidine gluconate.", "content": "Different sensitivities of type 1 and type 2 Herpes simplex virus to sodium p-chloromercuribenzoate and chlorhexidine gluconate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373749"}
{"pmid": "4373750", "title": "Intranuclear binding of hydrocortisone in liver and thymus tissues.", "content": "Intranuclear binding of hydrocortisone in liver and thymus tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373750"}
{"pmid": "4373742", "title": "Prudence in orthopedic surgery.", "content": "Prudence in orthopedic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373742"}
{"pmid": "4373744", "title": "Practical approach to endocrine problems in office practice.", "content": "Practical approach to endocrine problems in office practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373744"}
{"pmid": "4373751", "title": "The effect of chronic alveolar hypoxia on lung and serum angiotensin I converting enzyme activity.", "content": "The effect of chronic alveolar hypoxia on lung and serum angiotensin I converting enzyme activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373751"}
{"pmid": "4373753", "title": "Differential effects of two strains of BCG on transplantation immunity to SV40-induced tumors in hamsters.", "content": "Differential effects of two strains of BCG on transplantation immunity to SV40-induced tumors in hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373753"}
{"pmid": "4373752", "title": "Mode of action and biological properties of insoluble interferon.", "content": "Mode of action and biological properties of insoluble interferon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373752"}
{"pmid": "4373754", "title": "Evidence for chronic viral infections in human arteries.", "content": "Evidence for chronic viral infections in human arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373754"}
{"pmid": "4373755", "title": "Parathyroid hormone activation of adenylate cyclase in liver.", "content": "Parathyroid hormone activation of adenylate cyclase in liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373755"}
{"pmid": "4373756", "title": "The role of the renin--angiotensin system in experimental renal hypertension in dogs.", "content": "The role of the renin--angiotensin system in experimental renal hypertension in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373756"}
{"pmid": "4373743", "title": "Some new developments in the field of immunotherapy.", "content": "Some new developments in the field of immunotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373743"}
{"pmid": "4373757", "title": "Effects of ions on adrenocorticotropin-sensitive adenylate cyclase of rat adrenals.", "content": "Effects of ions on adrenocorticotropin-sensitive adenylate cyclase of rat adrenals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373757"}
{"pmid": "4373758", "title": "Isolation and characterization of an echovirus, possible \"prime\" strain of echovirus type 12.", "content": "Isolation and characterization of an echovirus, possible \"prime\" strain of echovirus type 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373758"}
{"pmid": "4373759", "title": "Quantitative study on leucine incorporation in multinucleate cells induced by Sendai virus.", "content": "Quantitative study on leucine incorporation in multinucleate cells induced by Sendai virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373759"}
{"pmid": "4373760", "title": "Neonatal hyperthyroidism and maturation of the rat hypothalamo-hypophyseal-adrenal axis.", "content": "Neonatal hyperthyroidism and maturation of the rat hypothalamo-hypophyseal-adrenal axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373760"}
{"pmid": "4373761", "title": "Rhinoviruses: an antigenic study of the prototype virus strains.", "content": "Rhinoviruses: an antigenic study of the prototype virus strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373761"}
{"pmid": "4373763", "title": "Studies on the effect of collagenase and hyaluronidase on glycogen content of isolated rat liver parenchymal cells.", "content": "Studies on the effect of collagenase and hyaluronidase on glycogen content of isolated rat liver parenchymal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373763"}
{"pmid": "4373762", "title": "Effect of phenylalanine and p-chlorophenylalanine administration on the development of rat brain 2',3'-cyclic nucleotide 3'-phosphohydrolase.", "content": "Effect of phenylalanine and p-chlorophenylalanine administration on the development of rat brain 2',3'-cyclic nucleotide 3'-phosphohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373762"}
{"pmid": "4373764", "title": "Acute renal failure in disseminated intravascular coagulation. Experimental studies of the induction and prevention of renal fibrin deposition.", "content": "Acute renal failure in disseminated intravascular coagulation. Experimental studies of the induction and prevention of renal fibrin deposition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373764"}
{"pmid": "4373765", "title": "Antiviral activity of selected biguanide derivatives.", "content": "Antiviral activity of selected biguanide derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373765"}
{"pmid": "4373766", "title": "Effects of papaverine on smooth muscle and their mechanisms.", "content": "Effects of papaverine on smooth muscle and their mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373766"}
{"pmid": "4373767", "title": "Influence of dietary sorbitol on some enzymes linked to glucose metabolism.", "content": "Influence of dietary sorbitol on some enzymes linked to glucose metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373767"}
{"pmid": "4373768", "title": "Inhibition of phosphodiesterase activity in brain cortical slices from guinea pig and rat.", "content": "Inhibition of phosphodiesterase activity in brain cortical slices from guinea pig and rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373768"}
{"pmid": "4373770", "title": "The effects of ACTH- and vasopressin- analogues on CO2-induced retrograde amnesia in rats.", "content": "The effects of ACTH- and vasopressin- analogues on CO2-induced retrograde amnesia in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373770"}
{"pmid": "4373769", "title": "Central beta-adrenoceptor sites and ouabain action.", "content": "Central beta-adrenoceptor sites and ouabain action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373769"}
{"pmid": "4373772", "title": "The in vitro effect of different substrates and high potassium concentration on the respiratory rate of slices, cell suspension and homogenate of brain.", "content": "The in vitro effect of different substrates and high potassium concentration on the respiratory rate of slices, cell suspension and homogenate of brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373772"}
{"pmid": "4373773", "title": "Involvement of cyclic-AMP in changes of the structuredness of cytoplasmic matrix (SCM).", "content": "Involvement of cyclic-AMP in changes of the structuredness of cytoplasmic matrix (SCM).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373773"}
{"pmid": "4373774", "title": "ESR investigations on radical formation after ultraviolet irradiation of trypsin in various polar and nonpolar media.", "content": "ESR investigations on radical formation after ultraviolet irradiation of trypsin in various polar and nonpolar media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373774"}
{"pmid": "4373776", "title": "Glomus tympanicum and glomus jugulare tumors.", "content": "Glomus tympanicum and glomus jugulare tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373776"}
{"pmid": "4373775", "title": "Photosensitization of small peptides by proflavine: an E.S.R. study at low temperature.", "content": "Photosensitization of small peptides by proflavine: an E.S.R. study at low temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373775"}
{"pmid": "4373779", "title": "Immunofluorescence antibodies in human sera to antigens in cells of a type C virus producing human culture of tumor origin.", "content": "Immunofluorescence antibodies in human sera to antigens in cells of a type C virus producing human culture of tumor origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373779"}
{"pmid": "4373777", "title": "Malignant lesions of the ear.", "content": "Malignant lesions of the ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373777"}
{"pmid": "4373778", "title": "Oncoduction. A unifying hypothesis of viral carcinogenesis.", "content": "Oncoduction. A unifying hypothesis of viral carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373778"}
{"pmid": "4373780", "title": "Mechanism of cytolysis by thymus-derived lymphocytes. Implications in tumor immunity.", "content": "Mechanism of cytolysis by thymus-derived lymphocytes. Implications in tumor immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373780"}
{"pmid": "4373781", "title": "Host immune response to virus-induced tumors. Some recent concepts.", "content": "Host immune response to virus-induced tumors. Some recent concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373781"}
{"pmid": "4373782", "title": "Antigenic analysis of transformed and nontransformed cells from human neoplasms.", "content": "Antigenic analysis of transformed and nontransformed cells from human neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373782"}
{"pmid": "4373783", "title": "Antigenic expression as a determining factor of tumor growth in Gross' virus lymphoma.", "content": "Antigenic expression as a determining factor of tumor growth in Gross' virus lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373783"}
{"pmid": "4373784", "title": "Tumor-specific antigens and reexpression of fetal antigens in mammalian cells.", "content": "Tumor-specific antigens and reexpression of fetal antigens in mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373784"}
{"pmid": "4373785", "title": "Vaccine production as a unit process.", "content": "Vaccine production as a unit process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373785"}
{"pmid": "4373790", "title": "Relative DNA contents of fibroblast nuclei after collagenase digestion.", "content": "Relative DNA contents of fibroblast nuclei after collagenase digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373790"}
{"pmid": "4373791", "title": "Control of exocrine pancreas secretion in vitro: a review.", "content": "Control of exocrine pancreas secretion in vitro: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373791"}
{"pmid": "4373792", "title": "Carcinoma of the cervix and herpes hominis (simplex) type 2 virus infection.", "content": "Carcinoma of the cervix and herpes hominis (simplex) type 2 virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373792"}
{"pmid": "4373795", "title": "Slow potential changes evoked in nucleus medialis dorsalis of the thalamus by stimulation of the amygdaloid nuclear complex.", "content": "Slow potential changes evoked in nucleus medialis dorsalis of the thalamus by stimulation of the amygdaloid nuclear complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373795"}
{"pmid": "4373796", "title": "Uneven distribution of phospholipids in rat liver inner mitochondrial membranes.", "content": "Uneven distribution of phospholipids in rat liver inner mitochondrial membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373796"}
{"pmid": "4373798", "title": "Distribution of tumours in Uganda.", "content": "Distribution of tumours in Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373798"}
{"pmid": "4373799", "title": "Tumours of the female genitalia.", "content": "Tumours of the female genitalia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373799"}
{"pmid": "4373800", "title": "Malignant tumours of the kidney, bladder and urethra.", "content": "Malignant tumours of the kidney, bladder and urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373800"}
{"pmid": "4373801", "title": "Tumours of endocrine glands.", "content": "Tumours of endocrine glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373801"}
{"pmid": "4373802", "title": "Tumours of bone and jaw.", "content": "Tumours of bone and jaw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373802"}
{"pmid": "4373803", "title": "Soft tissue tumours.", "content": "Soft tissue tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373803"}
{"pmid": "4373804", "title": "Childhood tumours.", "content": "Childhood tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373804"}
{"pmid": "4373805", "title": "Metabolic effects of seizures.", "content": "Metabolic effects of seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373805"}
{"pmid": "4373806", "title": "Psychiatric disturbances in endocrine disease: some issues for research.", "content": "Psychiatric disturbances in endocrine disease: some issues for research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373806"}
{"pmid": "4373807", "title": "Histamine induced changes in pulmonary guanosine-3',5'-cyclic monophosphate (cGMP) and adenosine-3',5'-cyclic monophosphate (cAMP) levels in mice following sensitization by Bordetella pertussis and/or propranolol.", "content": "Histamine induced changes in pulmonary guanosine-3',5'-cyclic monophosphate (cGMP) and adenosine-3',5'-cyclic monophosphate (cAMP) levels in mice following sensitization by Bordetella pertussis and/or propranolol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373807"}
{"pmid": "4373836", "title": "Clostridium perfringens (Cl. welchii) in the human gastro-intestinal tract.", "content": "Clostridium perfringens (Cl. welchii) in the human gastro-intestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373836"}
{"pmid": "4373837", "title": "Viruses associated with the healthy individual.", "content": "Viruses associated with the healthy individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373837"}
{"pmid": "4373839", "title": "The normal microbial flora of the skin.", "content": "The normal microbial flora of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373839"}
{"pmid": "4373838", "title": "The normal microbial flora of the mouth.", "content": "The normal microbial flora of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373838"}
{"pmid": "4373840", "title": "Range of action of the mechanism that repairs damage induced by certain chemical agents in Escherichia coli K-12.", "content": "Range of action of the mechanism that repairs damage induced by certain chemical agents in Escherichia coli K-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373840"}
{"pmid": "4373843", "title": "Heterotransplantation of human malignant neoplasms to the mouse mutant nude.", "content": "Heterotransplantation of human malignant neoplasms to the mouse mutant nude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373843"}
{"pmid": "4373844", "title": "Alteration of cardiac contractility and hemodynamics by phosphodiesterase inhibition.", "content": "Alteration of cardiac contractility and hemodynamics by phosphodiesterase inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373844"}
{"pmid": "4373846", "title": "Cytomegalovirus antigen-antibody complexes in biopsy specimens in renal allograft rejection.", "content": "Cytomegalovirus antigen-antibody complexes in biopsy specimens in renal allograft rejection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373846"}
{"pmid": "4373845", "title": "Effect of portacaval shunt on hepatic Krebs-Henseleit enzymes in dogs.", "content": "Effect of portacaval shunt on hepatic Krebs-Henseleit enzymes in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373845"}
{"pmid": "4373847", "title": "Immunosuppressive plasma factors in transplant recipients with viral infections.", "content": "Immunosuppressive plasma factors in transplant recipients with viral infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373847"}
{"pmid": "4373848", "title": "Complete protection of severely damaged kidneys by a silica gel plasma perfusate.", "content": "Complete protection of severely damaged kidneys by a silica gel plasma perfusate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373848"}
{"pmid": "4373849", "title": "Serum albumin alterations during experimental sepsis.", "content": "Serum albumin alterations during experimental sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373849"}
{"pmid": "4373850", "title": "Cholera toxin as a suppressor of in vivo cell-mediated immunity.", "content": "Cholera toxin as a suppressor of in vivo cell-mediated immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373850"}
{"pmid": "4373851", "title": "Morphologic evidence of direct innervation of parietal cells in rodent gastric mucosa.", "content": "Morphologic evidence of direct innervation of parietal cells in rodent gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373851"}
{"pmid": "4373852", "title": "Calcium influx in gastric acid secretion.", "content": "Calcium influx in gastric acid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373852"}
{"pmid": "4373853", "title": "Role of cyclic AMP system in humorally stimulated gastric acid secretion.", "content": "Role of cyclic AMP system in humorally stimulated gastric acid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373853"}
{"pmid": "4373854", "title": "Immunochemotherapy of hepatoma in rats.", "content": "Immunochemotherapy of hepatoma in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373854"}
{"pmid": "4373856", "title": "Estrogens and development of immobilization osteoporosis in rats.", "content": "Estrogens and development of immobilization osteoporosis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373856"}
{"pmid": "4373855", "title": "Lymph flow augmentation secondary to increases in serum calcium.", "content": "Lymph flow augmentation secondary to increases in serum calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373855"}
{"pmid": "4373857", "title": "Neurotrophism in relation to muscle and nerve grafts in rats.", "content": "Neurotrophism in relation to muscle and nerve grafts in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373857"}
{"pmid": "4373858", "title": "Renin-angiotensin I activity in renin lymph during acute ureteral obstruction.", "content": "Renin-angiotensin I activity in renin lymph during acute ureteral obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373858"}
{"pmid": "4373859", "title": "Action of alpha receptors of sympathetic nervous system on urethra and its vasculature.", "content": "Action of alpha receptors of sympathetic nervous system on urethra and its vasculature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373859"}
{"pmid": "4373860", "title": "Induction of aerobic metabolism by phosphocreatine following hemorrhagic shock.", "content": "Induction of aerobic metabolism by phosphocreatine following hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373860"}
{"pmid": "4373861", "title": "Deoxycorticosterone inhibits a viral tumor.", "content": "Deoxycorticosterone inhibits a viral tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373861"}
{"pmid": "4373862", "title": "Functional aspects of reinnervation of skin grafts.", "content": "Functional aspects of reinnervation of skin grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373862"}
{"pmid": "4373863", "title": "Development of the trigeminal ganglion.", "content": "Development of the trigeminal ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373863"}
{"pmid": "4373868", "title": "The inhibition of cancer cell stickness by the methylxanthine derivative pentoxifylline (BL 191).", "content": "The inhibition of cancer cell stickness by the methylxanthine derivative pentoxifylline (BL 191).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373868"}
{"pmid": "4373869", "title": "Contact activation of heparinized plasma.", "content": "Contact activation of heparinized plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373869"}
{"pmid": "4373870", "title": "Stimulation of human platelet adenylate cyclase by prostaglandin D2.", "content": "Stimulation of human platelet adenylate cyclase by prostaglandin D2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373870"}
{"pmid": "4373871", "title": "Relaxation of retracted clots: a thrombelastographic study.", "content": "Relaxation of retracted clots: a thrombelastographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373871"}
{"pmid": "4373874", "title": "Hypouricemic, mentally retarded infant with a defect of 5-phosphoribosyl-1-pyrophosphate synthetase of erythrocytes.", "content": "Hypouricemic, mentally retarded infant with a defect of 5-phosphoribosyl-1-pyrophosphate synthetase of erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373874"}
{"pmid": "4373875", "title": "Hepatitis associated antigen in various clinical conditions especially in primary hepatoma and metastatic liver cancer.", "content": "Hepatitis associated antigen in various clinical conditions especially in primary hepatoma and metastatic liver cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373875"}
{"pmid": "4373879", "title": "The effect of Dianabol on certain cell energy processes in postirradiation disease.", "content": "The effect of Dianabol on certain cell energy processes in postirradiation disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373879"}
{"pmid": "4373880", "title": "Oxathiol effects on 210Po retention in the dogs' organs.", "content": "Oxathiol effects on 210Po retention in the dogs' organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373880"}
{"pmid": "4373881", "title": "The nuclear envelope: current problems of structure and of function.", "content": "The nuclear envelope: current problems of structure and of function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373881"}
{"pmid": "4373882", "title": "Feedback control mechanisms in micro-organisms and efficiency of growth.", "content": "Feedback control mechanisms in micro-organisms and efficiency of growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373882"}
{"pmid": "4373883", "title": "Lipid-protein interactions in the structure of biological membranes.", "content": "Lipid-protein interactions in the structure of biological membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373883"}
{"pmid": "4373884", "title": "Progress in and deterrents to orthotopic liver transplantation, with special reference to survival, resistance to hyperacute rejection, and biliary duct reconstruction.", "content": "Progress in and deterrents to orthotopic liver transplantation, with special reference to survival, resistance to hyperacute rejection, and biliary duct reconstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373884"}
{"pmid": "4373892", "title": "Observations on the influence of ACTH on adrenal cholesterol metabolism.", "content": "Observations on the influence of ACTH on adrenal cholesterol metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373892"}
{"pmid": "4373893", "title": "Some observations on arterial and venous levels of angiotensin II in man.", "content": "Some observations on arterial and venous levels of angiotensin II in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373893"}
{"pmid": "4373894", "title": "Biosynthesis, secretion and mechanism of action of parathyroid hormone.", "content": "Biosynthesis, secretion and mechanism of action of parathyroid hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373894"}
{"pmid": "4373895", "title": "Radiographic diagnosis of joint diseases.", "content": "Radiographic diagnosis of joint diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373895"}
{"pmid": "4373896", "title": "Interpretation of abdominal survey radiographs.", "content": "Interpretation of abdominal survey radiographs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373896"}
{"pmid": "4373897", "title": "Studies of feline viral rhinotracheitis vaccine.", "content": "Studies of feline viral rhinotracheitis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373897"}
{"pmid": "4373899", "title": "Virus-induced cell pathology as viewed in the scanning electron microscope.", "content": "Virus-induced cell pathology as viewed in the scanning electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373899"}
{"pmid": "4373898", "title": "Placental and fetal manifestations of cytomegalovirus infection.", "content": "Placental and fetal manifestations of cytomegalovirus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373898"}
{"pmid": "4373900", "title": "Evolution and selective reduction of hormonal secretion in the mammotropic pituitary tumor (MtT-F4).", "content": "Evolution and selective reduction of hormonal secretion in the mammotropic pituitary tumor (MtT-F4).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373900"}
{"pmid": "4373936", "title": "A new look at infectious gastroenteritis.", "content": "A new look at infectious gastroenteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373936"}
{"pmid": "4373962", "title": "A simple, kinetic procedure for the optimized determination of the activity of serum glutamate dehydrogenase (EC 1.4.1.2.) with an enzyme analyzer.", "content": "A simple, kinetic procedure for the optimized determination of the activity of serum glutamate dehydrogenase (EC 1.4.1.2.) with an enzyme analyzer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373962"}
{"pmid": "4373965", "title": "Analysis of catecholamines, serotonin and their metabolites by ion pair partition and modern liquid chromatography.", "content": "Analysis of catecholamines, serotonin and their metabolites by ion pair partition and modern liquid chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373965"}
{"pmid": "4373966", "title": "True Arrhenius relationship of human lactate dehydrogenase.", "content": "True Arrhenius relationship of human lactate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373966"}
{"pmid": "4373967", "title": "The effect of dilution and substrate repletion on the fluormetric determination of lactate dehydrogenase (LDH) isoenzymes of sera with high LDH activities.", "content": "The effect of dilution and substrate repletion on the fluormetric determination of lactate dehydrogenase (LDH) isoenzymes of sera with high LDH activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373967"}
{"pmid": "4373968", "title": "Determination of plasma cortisol by an enzymic fluorometric method.", "content": "Determination of plasma cortisol by an enzymic fluorometric method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373968"}
{"pmid": "4373969", "title": "Preparation of specific solid supports from p-nitrophenyl substituted polyacrylamide gels. Affinity chromatography of cAMP specific enzymes.", "content": "Preparation of specific solid supports from p-nitrophenyl substituted polyacrylamide gels. Affinity chromatography of cAMP specific enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373969"}
{"pmid": "4373970", "title": "Specific coupling of nicotinamide adenine dinucleotide (NAD) to polymer supports.", "content": "Specific coupling of nicotinamide adenine dinucleotide (NAD) to polymer supports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373970"}
{"pmid": "4373971", "title": "A comparison of three methods of human plasma low density lipoprotein analysis.", "content": "A comparison of three methods of human plasma low density lipoprotein analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373971"}
{"pmid": "4373972", "title": "Preparation and properties of an antibody to human low density lipoprotein.", "content": "Preparation and properties of an antibody to human low density lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373972"}
{"pmid": "4373973", "title": "Analysis of metobolites in human biopsies by means of analytical isotachophoresis.", "content": "Analysis of metobolites in human biopsies by means of analytical isotachophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373973"}
{"pmid": "4373974", "title": "Application of electron spin resonance to the study of alpha-amylase activity.", "content": "Application of electron spin resonance to the study of alpha-amylase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373974"}
{"pmid": "4373975", "title": "Circadian rhythm of the renin-angiotensin-aldosterone system.", "content": "Circadian rhythm of the renin-angiotensin-aldosterone system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373975"}
{"pmid": "4373976", "title": "Liver tumours in CF-1 mice exposed for limited periods to technical DDT.", "content": "Liver tumours in CF-1 mice exposed for limited periods to technical DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373976"}
{"pmid": "4373989", "title": "Studies on electron spin resonance of Cu2+ complexes with nucleosides.", "content": "Studies on electron spin resonance of Cu2+ complexes with nucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373989"}
{"pmid": "4373990", "title": "Solubilization of collagen fibrils by human leucocyte collagenase activated by rheumatoid synovial fluid.", "content": "Solubilization of collagen fibrils by human leucocyte collagenase activated by rheumatoid synovial fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373990"}
{"pmid": "4373991", "title": "The role of cyclic adenosine 3',5'-monophosphate in the synthesis of the enzymess of gamma-aminobutyrate breakdown in Escherichia coli K-12.", "content": "The role of cyclic adenosine 3',5'-monophosphate in the synthesis of the enzymess of gamma-aminobutyrate breakdown in Escherichia coli K-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373991"}
{"pmid": "4373992", "title": "The prevalence of hypertension in an unselected population, and the frequency of abnormalities of potassium, angiotensin II and aldosterone in hypertensive subjects.", "content": "The prevalence of hypertension in an unselected population, and the frequency of abnormalities of potassium, angiotensin II and aldosterone in hypertensive subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373992"}
{"pmid": "4373994", "title": "Borderline hypertension: correlation between the cardiac output and the vascular reactivity to norepinephrine.", "content": "Borderline hypertension: correlation between the cardiac output and the vascular reactivity to norepinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373994"}
{"pmid": "4373995", "title": "A correlation between plasma renin activity and the pressor response to angiotensin II.", "content": "A correlation between plasma renin activity and the pressor response to angiotensin II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373995"}
{"pmid": "4373997", "title": "On the decrease curve of leukemic cells and the treatment of acute leukemia.", "content": "On the decrease curve of leukemic cells and the treatment of acute leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373997"}
{"pmid": "4374002", "title": "Effect of phytohemagglutinin, basic protein and measles antigen on myo-(2-3H)inositol incorporation into phosphatidylinositol of lymphocytes from patients with multiple sclerosis.", "content": "Effect of phytohemagglutinin, basic protein and measles antigen on myo-(2-3H)inositol incorporation into phosphatidylinositol of lymphocytes from patients with multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374002"}
{"pmid": "4374003", "title": "The cerebral copper-protein complexes in hepato-lenticular degeneration studied by means of electron-spin-resonance technique.", "content": "The cerebral copper-protein complexes in hepato-lenticular degeneration studied by means of electron-spin-resonance technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374003"}
{"pmid": "4374004", "title": "Peripheral nerve involvement in leprosy: quantitative histologic aspects.", "content": "Peripheral nerve involvement in leprosy: quantitative histologic aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374004"}
{"pmid": "4374005", "title": "Chloroquine-enhanced cerebellovascular changes in nutritionally imbalanced chicks.", "content": "Chloroquine-enhanced cerebellovascular changes in nutritionally imbalanced chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374005"}
{"pmid": "4373996", "title": "Problems of the management of insulinomas. Review of 132 cases treated with medical measures.", "content": "Problems of the management of insulinomas. Review of 132 cases treated with medical measures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4373996"}
{"pmid": "4374006", "title": "Primary intracranial adenoid cystic carcinoma (cylindroma). An electron microscopic study.", "content": "Primary intracranial adenoid cystic carcinoma (cylindroma). An electron microscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374006"}
{"pmid": "4374007", "title": "New linear accelerator for radiation therapy. A preliminary report.", "content": "New linear accelerator for radiation therapy. A preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374007"}
{"pmid": "4374008", "title": "Fast neutron therapy. Past and present.", "content": "Fast neutron therapy. Past and present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374008"}
{"pmid": "4374009", "title": "Corrections of isodose diagrams for 60Co and 35 MeV electrons at penetration of lung tissue.", "content": "Corrections of isodose diagrams for 60Co and 35 MeV electrons at penetration of lung tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374009"}
{"pmid": "4374010", "title": "Physical aspects on dose planning in treatment of mammary carcinoma.", "content": "Physical aspects on dose planning in treatment of mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374010"}
{"pmid": "4374011", "title": "Radiation dosimetry with exoelectron emitting materials.", "content": "Radiation dosimetry with exoelectron emitting materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374011"}
{"pmid": "4374012", "title": "Dosimetric investigation of postoperative irradiation of regional lymph nodes in mammary carcinoma.", "content": "Dosimetric investigation of postoperative irradiation of regional lymph nodes in mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374012"}
{"pmid": "4374013", "title": "Individual plastic casts for radiation treatment.", "content": "Individual plastic casts for radiation treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374013"}
{"pmid": "4374014", "title": "Small gas-tight ionization chambers for absorbed dose control during radiation therapy.", "content": "Small gas-tight ionization chambers for absorbed dose control during radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374014"}
{"pmid": "4374015", "title": "The radionuclide imaging process.", "content": "The radionuclide imaging process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374015"}
{"pmid": "4374016", "title": "Computerised system for scintigraphy.", "content": "Computerised system for scintigraphy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374016"}
{"pmid": "4374017", "title": "Spectrum stabilization on a whole body counter with three detectors.", "content": "Spectrum stabilization on a whole body counter with three detectors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374017"}
{"pmid": "4374018", "title": "Quantitative evaluation of isotope nephrograms.", "content": "Quantitative evaluation of isotope nephrograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374018"}
{"pmid": "4374019", "title": "Computer evaluation of scintigraphic images.", "content": "Computer evaluation of scintigraphic images.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374019"}
{"pmid": "4374021", "title": "Computer processing of scintigraphic images.", "content": "Computer processing of scintigraphic images.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374021"}
{"pmid": "4374020", "title": "The mineral content in bone. Measured by means of 27.5 keV radiation from 125I.", "content": "The mineral content in bone. Measured by means of 27.5 keV radiation from 125I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374020"}
{"pmid": "4374022", "title": "Digital stereoscintigraphy.", "content": "Digital stereoscintigraphy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374022"}
{"pmid": "4374023", "title": "The dot counting method in scintigraphy.", "content": "The dot counting method in scintigraphy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374023"}
{"pmid": "4374025", "title": "Measurement of the resolution of a gamma camera system.", "content": "Measurement of the resolution of a gamma camera system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374025"}
{"pmid": "4374024", "title": "A new whole body monitoring laboratory.", "content": "A new whole body monitoring laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374024"}
{"pmid": "4374026", "title": "Transit dose in extracorporeal blood irradiation devices measured by means of thermoluminescence.", "content": "Transit dose in extracorporeal blood irradiation devices measured by means of thermoluminescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374026"}
{"pmid": "4374027", "title": "Cryosurgery. Principles and application to tonsillectomy.", "content": "Cryosurgery. Principles and application to tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374027"}
{"pmid": "4374028", "title": "Dosimetry by extracorporeal irradiation of blood.", "content": "Dosimetry by extracorporeal irradiation of blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374028"}
{"pmid": "4374030", "title": "Optical data processing. Principles and application to EEG audiometry.", "content": "Optical data processing. Principles and application to EEG audiometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374030"}
{"pmid": "4374029", "title": "Measuring methods for clinical investigation of the middle ear.", "content": "Measuring methods for clinical investigation of the middle ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374029"}
{"pmid": "4374031", "title": "Beta and gamma radiochromatography with spark chambers.", "content": "Beta and gamma radiochromatography with spark chambers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374031"}
{"pmid": "4374032", "title": "Treatment couch according to the Malmö system.", "content": "Treatment couch according to the Malmö system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374032"}
{"pmid": "4374033", "title": "Safety aspects of modern medical linear accelerators.", "content": "Safety aspects of modern medical linear accelerators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374033"}
{"pmid": "4374034", "title": "Instrument for dose rate measurements in gynaecologic radiation therapy.", "content": "Instrument for dose rate measurements in gynaecologic radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374034"}
{"pmid": "4374036", "title": "Analytic approximation of the dose distribution from a 6 MeV linear accelerator.", "content": "Analytic approximation of the dose distribution from a 6 MeV linear accelerator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374036"}
{"pmid": "4374035", "title": "Skin doses for electrons in the energy range 10 to 33 MeV. Measurements with thermoluminescence dosimeters.", "content": "Skin doses for electrons in the energy range 10 to 33 MeV. Measurements with thermoluminescence dosimeters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374035"}
{"pmid": "4374037", "title": "Depth dose near the surface by fast electron irradiation. Measurements with thermoluminescence dosimetry.", "content": "Depth dose near the surface by fast electron irradiation. Measurements with thermoluminescence dosimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374037"}
{"pmid": "4374038", "title": "Automation in radiation therapy.", "content": "Automation in radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374038"}
{"pmid": "4374039", "title": "Treatment of Hodgkin's disease by radiation therapy.", "content": "Treatment of Hodgkin's disease by radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374039"}
{"pmid": "4374040", "title": "A digital electrometer.", "content": "A digital electrometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374040"}
{"pmid": "4374041", "title": "Irradiation of the thorax. Comparison between 60Co gamma rays, 6 MeV roentgen rays and 30 MeV electrons.", "content": "Irradiation of the thorax. Comparison between 60Co gamma rays, 6 MeV roentgen rays and 30 MeV electrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374041"}
{"pmid": "4374042", "title": "Radiophysical means for adequate radiation therapy with supervoltage apparatus at Radiumhemmet.", "content": "Radiophysical means for adequate radiation therapy with supervoltage apparatus at Radiumhemmet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374042"}
{"pmid": "4374043", "title": "The importance of two independent integrating monitoring systems in medical accelerators.", "content": "The importance of two independent integrating monitoring systems in medical accelerators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374043"}
{"pmid": "4374044", "title": "45 MeV betatron for radiation therapy.", "content": "45 MeV betatron for radiation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374044"}
{"pmid": "4374045", "title": "The effect of cadmium on catecholamines and angiotensin responses in the dog kidney.", "content": "The effect of cadmium on catecholamines and angiotensin responses in the dog kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374045"}
{"pmid": "4374047", "title": "Effect of immunization with fetal cells on adenovirus-12 oncogenesis.", "content": "Effect of immunization with fetal cells on adenovirus-12 oncogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374047"}
{"pmid": "4374046", "title": "Ultrastructure of the ribonucleoprotein and messenger-like ribonucleic acid of the polyribosomes isolated from Rous sarcoma virus-induced mouse ascites sarcoma cells.", "content": "Ultrastructure of the ribonucleoprotein and messenger-like ribonucleic acid of the polyribosomes isolated from Rous sarcoma virus-induced mouse ascites sarcoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374046"}
{"pmid": "4374048", "title": "The role of cyclic nucleotide on fetal and neonantal erythropoiesis.", "content": "The role of cyclic nucleotide on fetal and neonantal erythropoiesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374048"}
{"pmid": "4374049", "title": "Attempts to isolate virus from human brain tumors.", "content": "Attempts to isolate virus from human brain tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374049"}
{"pmid": "4374050", "title": "Epstein-Barr virus (EBV) infections in army recruits.", "content": "Epstein-Barr virus (EBV) infections in army recruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374050"}
{"pmid": "4374051", "title": "Advances in penicillin research.", "content": "Advances in penicillin research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374051"}
{"pmid": "4374052", "title": "An outbreak of arthrogryposis and hydranencephaly syndrome affecting calves in Israel: a retrospective epidemiological study.", "content": "An outbreak of arthrogryposis and hydranencephaly syndrome affecting calves in Israel: a retrospective epidemiological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374052"}
{"pmid": "4374053", "title": "Studies of the nicotinic receptor-response mechanism in Torpedo postsynaptic membranes.", "content": "Studies of the nicotinic receptor-response mechanism in Torpedo postsynaptic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374053"}
{"pmid": "4374054", "title": "Membranes of adrenal medulla: their role in exocytosis.", "content": "Membranes of adrenal medulla: their role in exocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374054"}
{"pmid": "4374055", "title": "Binding of ADP and ATP to mitochondrial protein and its possible involvement in the mechanism of oxidative phosphorylation.", "content": "Binding of ADP and ATP to mitochondrial protein and its possible involvement in the mechanism of oxidative phosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374055"}
{"pmid": "4374056", "title": "Modification of the secretory granule during secretion in the rat parotid gland.", "content": "Modification of the secretory granule during secretion in the rat parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374056"}
{"pmid": "4374057", "title": "Interactions of membranes, microfilaments, and microtubules in endocytosis and exocytosis.", "content": "Interactions of membranes, microfilaments, and microtubules in endocytosis and exocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374057"}
{"pmid": "4374058", "title": "The molecular organization of the beta granule of the islets of Langerhans.", "content": "The molecular organization of the beta granule of the islets of Langerhans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374058"}
{"pmid": "4374059", "title": "Molecular basis of enzyme secretion by the exocrine pancreas.", "content": "Molecular basis of enzyme secretion by the exocrine pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374059"}
{"pmid": "4374060", "title": "The relation between cholinergic and monoaminergic activity in the caudate nucleus.", "content": "The relation between cholinergic and monoaminergic activity in the caudate nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374060"}
{"pmid": "4374061", "title": "The pathology of Parkinsonism: a comparison of degenerations in cerebral cortex and brainstem.", "content": "The pathology of Parkinsonism: a comparison of degenerations in cerebral cortex and brainstem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374061"}
{"pmid": "4374062", "title": "Depigmentation in the nerve cells of the substantia nigra and locus ceruleus in Parkinsonism.", "content": "Depigmentation in the nerve cells of the substantia nigra and locus ceruleus in Parkinsonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374062"}
{"pmid": "4374063", "title": "Biochemistry of neuromelanin.", "content": "Biochemistry of neuromelanin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374063"}
{"pmid": "4374064", "title": "Free radicals in the human nervous system.", "content": "Free radicals in the human nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374064"}
{"pmid": "4374065", "title": "Dopaminergic involvement in hypothalamic function: extrahypothalamic and hypothalamic control. A neuroanatomical analysis.", "content": "Dopaminergic involvement in hypothalamic function: extrahypothalamic and hypothalamic control. A neuroanatomical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374065"}
{"pmid": "4374066", "title": "Catecholaminergic control of gonadotropin and prolactin secretion with particular reference to the possible participation of dopamine.", "content": "Catecholaminergic control of gonadotropin and prolactin secretion with particular reference to the possible participation of dopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374066"}
{"pmid": "4374067", "title": "Central noradrenergic neurons.", "content": "Central noradrenergic neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374067"}
{"pmid": "4374068", "title": "The role of brain catecholamines in the regulation of ACTH secretion.", "content": "The role of brain catecholamines in the regulation of ACTH secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374068"}
{"pmid": "4374069", "title": "Mechanisms involved in the control of extrapyramidal dysfunctions and in striatal dopamine synthesis.", "content": "Mechanisms involved in the control of extrapyramidal dysfunctions and in striatal dopamine synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374069"}
{"pmid": "4374070", "title": "The use of protoplasts and separated cells in plant virus research.", "content": "The use of protoplasts and separated cells in plant virus research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374070"}
{"pmid": "4374071", "title": "Remarks on the ultrastructure of type A, B, and C virus particles.", "content": "Remarks on the ultrastructure of type A, B, and C virus particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374071"}
{"pmid": "4374072", "title": "Plant viruses with a multipartite genome.", "content": "Plant viruses with a multipartite genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374072"}
{"pmid": "4374074", "title": "On the problem of heredity in hypersomnia, narcolepsy and dissociated sleep disturbances.", "content": "On the problem of heredity in hypersomnia, narcolepsy and dissociated sleep disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374074"}
{"pmid": "4374075", "title": "Trophoblastic disease I.", "content": "Trophoblastic disease I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374075"}
{"pmid": "4374076", "title": "Trophoblastic disease II. Trophoblastic invasion.", "content": "Trophoblastic disease II. Trophoblastic invasion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374076"}
{"pmid": "4374077", "title": "Trophoblastic disease III. Choriocarcinoma and related diseases.", "content": "Trophoblastic disease III. Choriocarcinoma and related diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374077"}
{"pmid": "4374078", "title": "Blood flow through the thyroid gland in rats.", "content": "Blood flow through the thyroid gland in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374078"}
{"pmid": "4374080", "title": "PR aside: initial results from NIMH's service program evaluation studies.", "content": "PR aside: initial results from NIMH's service program evaluation studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374080"}
{"pmid": "4374079", "title": "Vinca alkaloids. Experimental and clinical trials.", "content": "Vinca alkaloids. Experimental and clinical trials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374079"}
{"pmid": "4374081", "title": "The role of viruses in congenital defects.", "content": "The role of viruses in congenital defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374081"}
{"pmid": "4374082", "title": "Concomitant Mycoplasma and adenovirus infection in a family.", "content": "Concomitant Mycoplasma and adenovirus infection in a family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374082"}
{"pmid": "4374083", "title": "Radioimmunoassay of alpha-fetoprotein in human serum: clinical value in patients with liver diseases.", "content": "Radioimmunoassay of alpha-fetoprotein in human serum: clinical value in patients with liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374083"}
{"pmid": "4374084", "title": "Rational use of psychotropic drugs. I. Hypnotics.", "content": "Rational use of psychotropic drugs. I. Hypnotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374084"}
{"pmid": "4374085", "title": "Cushing's disease with cure by resection of a pituitary adenoma. Evidence against a primary hypothalamic defect.", "content": "Cushing's disease with cure by resection of a pituitary adenoma. Evidence against a primary hypothalamic defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374085"}
{"pmid": "4374086", "title": "Cell surface contributions to the malignant process.", "content": "Cell surface contributions to the malignant process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374086"}
{"pmid": "4374087", "title": "Statistical correlation of uveitis syndromes with virus titers.", "content": "Statistical correlation of uveitis syndromes with virus titers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374087"}
{"pmid": "4374088", "title": "Parathyroid hormone stimulation of glucose and urea production in isolated liver cells.", "content": "Parathyroid hormone stimulation of glucose and urea production in isolated liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374088"}
{"pmid": "4374089", "title": "Renal function in dogs with acute selective hepatic venous outflow block.", "content": "Renal function in dogs with acute selective hepatic venous outflow block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374089"}
{"pmid": "4374090", "title": "Facilitation of transmitter release at the mammalian neuromuscular junction.", "content": "Facilitation of transmitter release at the mammalian neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374090"}
{"pmid": "4374091", "title": "Effect of parathormone and cyclic adenosine monophosphate on renal bicarbonate reabsorption.", "content": "Effect of parathormone and cyclic adenosine monophosphate on renal bicarbonate reabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374091"}
{"pmid": "4374093", "title": "MEPP frequency distribution in rat diaphragm under vitamin E deficiency.", "content": "MEPP frequency distribution in rat diaphragm under vitamin E deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374093"}
{"pmid": "4374092", "title": "Alterations in pharmacologic receptor activity by dithiothreitol.", "content": "Alterations in pharmacologic receptor activity by dithiothreitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374092"}
{"pmid": "4374094", "title": "Effects of phosphate depletion and parathyroid hormone on renal glucose reabsorption.", "content": "Effects of phosphate depletion and parathyroid hormone on renal glucose reabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374094"}
{"pmid": "4374095", "title": "Theophylline, cyclic AMP, choleragen, and electrolyte transport by rabbit ileum.", "content": "Theophylline, cyclic AMP, choleragen, and electrolyte transport by rabbit ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374095"}
{"pmid": "4374096", "title": "Comparison of the biochemical composition of four preparations of contracting cardiac muscle.", "content": "Comparison of the biochemical composition of four preparations of contracting cardiac muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374096"}
{"pmid": "4374097", "title": "Partial resection of the liver for primary cholangiocarcinoma. Presentation of a successful case.", "content": "Partial resection of the liver for primary cholangiocarcinoma. Presentation of a successful case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374097"}
{"pmid": "4374098", "title": "Inhibition of gastric acid secretion by extract of WDHA tumor.", "content": "Inhibition of gastric acid secretion by extract of WDHA tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374098"}
{"pmid": "4374100", "title": "Enzymatic liberation of myogenic cells from adult rat muscle.", "content": "Enzymatic liberation of myogenic cells from adult rat muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374100"}
{"pmid": "4374101", "title": "Blood vessel wall characteristics in experimental hypertension.", "content": "Blood vessel wall characteristics in experimental hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374101"}
{"pmid": "4374103", "title": "Conference on the scientific basis of respiratory therapy. Aerosol therapy. Steroid and antibiotic aerosols.", "content": "Conference on the scientific basis of respiratory therapy. Aerosol therapy. Steroid and antibiotic aerosols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374103"}
{"pmid": "4374105", "title": "Extra-adrenal retroperitoneal paraganglioma.", "content": "Extra-adrenal retroperitoneal paraganglioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374105"}
{"pmid": "4374104", "title": "Intracellular metabolism of oxygen.", "content": "Intracellular metabolism of oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374104"}
{"pmid": "4374111", "title": "Accuracy, sensitivity, and specificity of electron spin resonance analysis of mineral constituents of irradiated tissues.", "content": "Accuracy, sensitivity, and specificity of electron spin resonance analysis of mineral constituents of irradiated tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374111"}
{"pmid": "4374102", "title": "The replication of herpes viruses.", "content": "The replication of herpes viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374102"}
{"pmid": "4374113", "title": "Treatment of shrinkage diseases of the conjunctiva.", "content": "Treatment of shrinkage diseases of the conjunctiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374113"}
{"pmid": "4374112", "title": "Ocular complications in renal transplant patients.", "content": "Ocular complications in renal transplant patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374112"}
{"pmid": "4374116", "title": "Pheromones as a means of genetic control of behavior.", "content": "Pheromones as a means of genetic control of behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374116"}
{"pmid": "4374118", "title": "Genetics of DNA tumor viruses.", "content": "Genetics of DNA tumor viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374118"}
{"pmid": "4374117", "title": "Regulation: positive control.", "content": "Regulation: positive control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374117"}
{"pmid": "4374119", "title": "Test method for the evaluation of virucidal efficacy of three common liquid surface disinfectants on a simulated environmental surface.", "content": "Test method for the evaluation of virucidal efficacy of three common liquid surface disinfectants on a simulated environmental surface. The Association of Official Analytical Chemists bacterial use-dilution test for evaluating liquid surface disinfectants was modified to determine the efficacy of three common environmental germicide compounds against representatives of four virus groups. Modifications were made to conform to the Environmental Protection Agency guidelines on virucidal testing procedures. Alterations included: the use of a concentrated tissue culture preparation of virus instead of a standard bacterial culture; HEp-2 tissue culture cells as a visible test system in place of standard nutrient broth; and controls to measure the virus titer end point and the toxicity of the disinfectant to the cell cultures. Comparison of control end points with results from the test proper were the measure of the effectiveness of the germicides against the viruses. Results are described which agree with those based on other methods previously reported.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374119"}
{"pmid": "4374120", "title": "Recovery of heated Clostridium perfringens type A spores on selective media.", "content": "Recovery of heated Clostridium perfringens type A spores on selective media. The enumeration of Clostridium perfringens spores on sulfite-polymyxin-sulfadiazine agar (SPS), tryptone-sulfite-neomycin agar (TSN), Shahidi-Ferguson-perfringens agar (SFP), tryptone-sulfite-cycloserine agar (TSC), and TSN lacking antibiotics (BASE) was studied. The spores were heated at 105 to 120 C by the capillary-tube method. The media were about equally efficient for the enumeration of heat-activated spores. Efficiency of the media for the recovery of spores surviving heat treatments at ultrahigh temperatures varied as follows: TSC >/= SFP > BASE > SPS > TSN. Greater recovery when survivors were enumerated on TSC or SFP was attributed to germination of injured spores by the lysozyme present in the egg yolk emulsion used in these media. Low recovery of survivors on TSN and SPS was due to both the absence of lysozyme and inhibition of injured spores by the selective agents of these media. Recovery of heated spores was reduced greatly by polymyxin, neomycin, and kanamycin, and slightly by sulfadiazine and D-cycloserine. The addition of lysozyme to SPS or TSN did not improve the percentage of heat-injured spores recovered because the selective agents of these media interfered with the action of lysozyme. The suitability of the selective media for the enumeration of survivors was greatly affected by the presence of certain foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374120"}
{"pmid": "4374121", "title": "Cold shock lethality and injury in Clostridium perfringens.", "content": "Cold shock lethality and injury in Clostridium perfringens. Several observations have been made in regard to cold shock lethality of Clostridium perfringens: (i) loss of viability was not consequence of exposure of the cells to air; (ii) stationary-phase cells were much more resistant to cold shock at 4 C than exponential-phase cells; (iii) at 4 C 96% of an initial population of exponential-phase cells was killed upon cold shock and 95% of the remaining population was killed within 90 min of continued exposure at 4 C; (iv) the minimal temperature differential for detectable cold shock lethality was between 17 and 23 C, and the maximum beyond which lethality was not appreciably increased was between 28 and 33 C. Up to 75% of viable cold-shocked cells were injured, as demonstrated by cold shocking late exponential-phase cells at 10 C and using differential plating procedure for recovery. Repair of injury was temperature dependent, and occurred in a complex medium and 0.1% peptone but not water. Nalidixic acid, chloramphenicol, and rifampin did not inhibit repair of injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374121"}
{"pmid": "4374123", "title": "Simplified method for the preparation of silica gel media.", "content": "Simplified method for the preparation of silica gel media. A simplified and reliable method for the preparation of a variety of silica gel media is described. The growth of common microorganisms on these media was examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374123"}
{"pmid": "4374122", "title": "Chemical disinfection of holding-tank sewage.", "content": "Chemical disinfection of holding-tank sewage. A number of chemical disinfectants were evaluated for their bactericidal and virucidal effectiveness in holding-tank sewage. It was found that the disinfection efficiencies of formaldehyde, benzalkonium chloride, cetylpyridinium chloride, and methylene blue were markedly improved if the pH of the sewage was raised from 8.0 to 10.5. When formaldehyde, benzalkonium chloride, and methylene blue were tested with either 2-week holding times with no sewage additions or 10-day holding times with daily sewage additions, disinfection effectiveness was maintained as long as the sewage pH was kept at 10.5 and the disinfectant concentration was kept at 100 mg/liter or more. Calcium hypochlorite, zinc sulfate, and phenol were found to be relatively ineffective disinfectants for holding-tank sewage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374122"}
{"pmid": "4374124", "title": "Response of ligated intestinal loops in chickens to the enterotoxin of Clostridium perfringens.", "content": "Response of ligated intestinal loops in chickens to the enterotoxin of Clostridium perfringens. Approximately 45-cm length of jejunoileum of 7-week-old chickens was found to be responsive and suitable for testing the enterotoxin of Clostridium perfringens by the ligated intestinal loop technique. Injections of 20 to 30 mug of enterotoxin per loop caused positive response of fluid accumulation. Chickens were found to be more convenient and economical for this purpose than other laboratory and domestic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374124"}
{"pmid": "4374125", "title": "Persistence of enteroviruses in lake water.", "content": "Persistence of enteroviruses in lake water. Two enteroviruses were inactivated more rapidly in a lake than in sterile lake water; then their coat proteins were degraded and, perhaps, used by microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374125"}
{"pmid": "4374126", "title": "The effect of Zn2+ ions on mitochondrial electron transport.", "content": "The effect of Zn2+ ions on mitochondrial electron transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374126"}
{"pmid": "4374127", "title": "Partial specificity of low-molecular weight RNA that stimulates RNA synthesis in various tissues.", "content": "Partial specificity of low-molecular weight RNA that stimulates RNA synthesis in various tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374127"}
{"pmid": "4374128", "title": "The effect of essential amino acid deprivation on macromolecular synthesis and nucleotide pool sizes in Neurospora crassa.", "content": "The effect of essential amino acid deprivation on macromolecular synthesis and nucleotide pool sizes in Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374128"}
{"pmid": "4374129", "title": "Alterations in glucose metabolism in chick embryo cells transformed by Rous sarcoma virus. Transformation-specific changes in the activities of key enzymes of the glycolytic and hexose monophosphate shunt pathways.", "content": "Alterations in glucose metabolism in chick embryo cells transformed by Rous sarcoma virus. Transformation-specific changes in the activities of key enzymes of the glycolytic and hexose monophosphate shunt pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374129"}
{"pmid": "4374130", "title": "Occurrence of initiation factor 2 in the postribosomal fraction and identification of an initiation inhibitor as elongation factor G.", "content": "Occurrence of initiation factor 2 in the postribosomal fraction and identification of an initiation inhibitor as elongation factor G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374130"}
{"pmid": "4374131", "title": "Concanavalin A and wheat germ agglutinin receptor activity of sialoglycopeptides isolated from the surface of Novikoff hepatoma cells.", "content": "Concanavalin A and wheat germ agglutinin receptor activity of sialoglycopeptides isolated from the surface of Novikoff hepatoma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374131"}
{"pmid": "4374132", "title": "Reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase and cytochrome b5 as electron carriers in NADH-supported cytochrome P-450 -dependent enzyme activities in liver microsomes.", "content": "Reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase and cytochrome b5 as electron carriers in NADH-supported cytochrome P-450 -dependent enzyme activities in liver microsomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374132"}
{"pmid": "4374133", "title": "Absence of high-affinity adenosine 3',5'-monophosphate binding sites from the cytosol of three hepatic-derived cell lines.", "content": "Absence of high-affinity adenosine 3',5'-monophosphate binding sites from the cytosol of three hepatic-derived cell lines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374133"}
{"pmid": "4374134", "title": "D2O effects on association behavior and binding properties of phospho- and dephospho-cytoplasmic malic dehydrogenase.", "content": "D2O effects on association behavior and binding properties of phospho- and dephospho-cytoplasmic malic dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374134"}
{"pmid": "4374135", "title": "Mechanism of aromatic hydroxylation. Properties of a model for pyridine nucleotide-dependent flavoprotein hydroxylases.", "content": "Mechanism of aromatic hydroxylation. Properties of a model for pyridine nucleotide-dependent flavoprotein hydroxylases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374135"}
{"pmid": "4374136", "title": "Resonance Raman spectra of the b- and c-type cytochromes of succinate-cytochrome c reductase.", "content": "Resonance Raman spectra of the b- and c-type cytochromes of succinate-cytochrome c reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374136"}
{"pmid": "4374137", "title": "Properties of purified kidney microsomal NADPH-cytochrome c reductase.", "content": "Properties of purified kidney microsomal NADPH-cytochrome c reductase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374137"}
{"pmid": "4374138", "title": "Structural implications derived from the analysis of electron paramagnetic resonance spectra of natural and artificial copper proteins.", "content": "Structural implications derived from the analysis of electron paramagnetic resonance spectra of natural and artificial copper proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374138"}
{"pmid": "4374139", "title": "Calcium-dependent cyclic nucleotide phosphodiesterase from glial tumor cells.", "content": "Calcium-dependent cyclic nucleotide phosphodiesterase from glial tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374139"}
{"pmid": "4374143", "title": "Pharmacological receptors and the control of cell function.", "content": "Pharmacological receptors and the control of cell function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374143"}
{"pmid": "4374144", "title": "Modulation of trigeminal reflexes during the REM state in brain transected cats.", "content": "Modulation of trigeminal reflexes during the REM state in brain transected cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374144"}
{"pmid": "4374145", "title": "Paget's disease of the breast.", "content": "Paget's disease of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374145"}
{"pmid": "4374147", "title": "Studies on a gram-positive hydrogen bacterium, Nocardia opaca 1 b. III. Purification, stability and some properties of the soluble hydrogen dehydrogenase.", "content": "Studies on a gram-positive hydrogen bacterium, Nocardia opaca 1 b. III. Purification, stability and some properties of the soluble hydrogen dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374147"}
{"pmid": "4374142", "title": "Advances in lipoprotein research. Biochemical and clinical aspects.", "content": "Advances in lipoprotein research. Biochemical and clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374142"}
{"pmid": "4374148", "title": "A phototrophic gliding filamentous bacterium of hot springs, Chloroflexus aurantiacus, gen. and sp. nov.", "content": "A phototrophic gliding filamentous bacterium of hot springs, Chloroflexus aurantiacus, gen. and sp. nov.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374148"}
{"pmid": "4374149", "title": "Characterization of amino acid pools in the vacuolar compartment of Saccharomyces cerevisiae.", "content": "Characterization of amino acid pools in the vacuolar compartment of Saccharomyces cerevisiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374149"}
{"pmid": "4374150", "title": "Linkage of the Salmonella typhimurium chromosomal loci encoding for the cytochrome-linked L-alpha-glycerophosphate dehydrogenase and amylomaltase activities.", "content": "Linkage of the Salmonella typhimurium chromosomal loci encoding for the cytochrome-linked L-alpha-glycerophosphate dehydrogenase and amylomaltase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374150"}
{"pmid": "4374156", "title": "Drug and sociotherapy in the aftercare of schizophrenic patients. III. Adjustment of nonrelapsed patients.", "content": "Drug and sociotherapy in the aftercare of schizophrenic patients. III. Adjustment of nonrelapsed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374156"}
{"pmid": "4374155", "title": "Drug and sociotherapy in the aftercare of schizophrenic patients. II. Two-year relapse rates.", "content": "Drug and sociotherapy in the aftercare of schizophrenic patients. II. Two-year relapse rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374155"}
{"pmid": "4374151", "title": "Regulation of biosynthesis of aspartate family amino acids in the photosynthetic bacterium Rhodopseudomonas palustris.", "content": "Regulation of biosynthesis of aspartate family amino acids in the photosynthetic bacterium Rhodopseudomonas palustris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374151"}
{"pmid": "4374157", "title": "Sleep amphetamine effects in MBDS and normal subjects.", "content": "Sleep amphetamine effects in MBDS and normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374157"}
{"pmid": "4374160", "title": "A simple method for the quantification of 140S particles of foot-and-mouth disease virus (FMDV).", "content": "A simple method for the quantification of 140S particles of foot-and-mouth disease virus (FMDV).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374160"}
{"pmid": "4374159", "title": "Complement-requiring neutralizing antibodies in cattle to infectious bovine rhinotracheitis virus.", "content": "Complement-requiring neutralizing antibodies in cattle to infectious bovine rhinotracheitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374159"}
{"pmid": "4374158", "title": "Analysis of minimal functions of simian virus 40. IV. Oncogenic transformation of syrian hamster kidney cells in vitro by beta-propiolactone inactivated sv40.", "content": "Analysis of minimal functions of simian virus 40. IV. Oncogenic transformation of syrian hamster kidney cells in vitro by beta-propiolactone inactivated sv40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374158"}
{"pmid": "4374161", "title": "Varicella virus isolation from spinal ganglion.", "content": "Varicella virus isolation from spinal ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374161"}
{"pmid": "4374163", "title": "Inhibition of giant cell formation by Compound 48-80 after infection with herpesvirus hominis. III. Binding of tritium-labelled Compound 48-80 to normal and infected cells and its action upon phosphatidyl-choline-biosynthesis.", "content": "Inhibition of giant cell formation by Compound 48-80 after infection with herpesvirus hominis. III. Binding of tritium-labelled Compound 48-80 to normal and infected cells and its action upon phosphatidyl-choline-biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374163"}
{"pmid": "4374162", "title": "Study of poliovirus multiplication in different animal species using photosensitized virus strains.", "content": "Study of poliovirus multiplication in different animal species using photosensitized virus strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374162"}
{"pmid": "4374166", "title": "The properties of intracellular paramyxovirus ribonucleoprotein in a nonpermissive system.", "content": "The properties of intracellular paramyxovirus ribonucleoprotein in a nonpermissive system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374166"}
{"pmid": "4374167", "title": "Improvement of methods for intratypic differentiation of polioviruses. I. Agar gel diffusion precipitation test with repeated addition of antigens for differentiation between wild and vaccine polioviruses type 1 and 2.", "content": "Improvement of methods for intratypic differentiation of polioviruses. I. Agar gel diffusion precipitation test with repeated addition of antigens for differentiation between wild and vaccine polioviruses type 1 and 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374167"}
{"pmid": "4374165", "title": "Herpes simplex viruses types 1 and 2. Type and strain specific characteristics affecting virus plaque formation.", "content": "Herpes simplex viruses types 1 and 2. Type and strain specific characteristics affecting virus plaque formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374165"}
{"pmid": "4374164", "title": "Inhibition of giant cell formation by Compound 48-80 after infection with herpesvirus hominis. IV. Compound 48-80, an inhibitor of choline kinase activity.", "content": "Inhibition of giant cell formation by Compound 48-80 after infection with herpesvirus hominis. IV. Compound 48-80, an inhibitor of choline kinase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374164"}
{"pmid": "4374168", "title": "Improvement of methods for intratypic differentiation of polioviruses. II. Use of strain-specific antisera cross-adsorbed with antigens of heterologous strains in agar gel diffusion precipitation test for differentiation between wild and vaccine strains of poliovirus typess 1,2 and 3.", "content": "Improvement of methods for intratypic differentiation of polioviruses. II. Use of strain-specific antisera cross-adsorbed with antigens of heterologous strains in agar gel diffusion precipitation test for differentiation between wild and vaccine strains of poliovirus typess 1,2 and 3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374168"}
{"pmid": "4374169", "title": "Improvement of methods for intratypic differentiation of polioviruses. III. Neutralization test with cross-adsorbed sera for differentiation between wild and vaccine strains of polioviruses.", "content": "Improvement of methods for intratypic differentiation of polioviruses. III. Neutralization test with cross-adsorbed sera for differentiation between wild and vaccine strains of polioviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374169"}
{"pmid": "4374170", "title": "Properties of SV40 rescued from actinomycin D-sensitive and actinomycin D-resistant transformed hamster cells. I. Lytic infection.", "content": "Properties of SV40 rescued from actinomycin D-sensitive and actinomycin D-resistant transformed hamster cells. I. Lytic infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374170"}
{"pmid": "4374175", "title": "Subependymal germinolysis.", "content": "Subependymal germinolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374175"}
{"pmid": "4374176", "title": "The thrombotic syndrome associated with carcinoma. A clinical and neuropathologic study.", "content": "The thrombotic syndrome associated with carcinoma. A clinical and neuropathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374176"}
{"pmid": "4374177", "title": "Regulation of lactate dehydrogenase activity in Actinomyces viscosus by adenosine-5'-triphosphate.", "content": "Regulation of lactate dehydrogenase activity in Actinomyces viscosus by adenosine-5'-triphosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374177"}
{"pmid": "4374178", "title": "Letter: Aerosol administration of the SA-2 vaccine strain of infectious laryngotracheitis virus.", "content": "Letter: Aerosol administration of the SA-2 vaccine strain of infectious laryngotracheitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374178"}
{"pmid": "4374183", "title": "Karyometric studies of thioacetamide-induced hepatomas.", "content": "Karyometric studies of thioacetamide-induced hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374183"}
{"pmid": "4374182", "title": "Hepatic parenchyma weight changes in the presence of primary and secondary tumors of the liver: a morphometric study.", "content": "Hepatic parenchyma weight changes in the presence of primary and secondary tumors of the liver: a morphometric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374182"}
{"pmid": "4374181", "title": "Structure and function of the stimulated adrenal cortex. 2. Early effects of ACTH on the ultrastructure of the zona fasciculata in dexamethasone--treated rats.", "content": "Structure and function of the stimulated adrenal cortex. 2. Early effects of ACTH on the ultrastructure of the zona fasciculata in dexamethasone--treated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374181"}
{"pmid": "4374185", "title": "Concentration of elongation factor 2 in rat skeletal muscle during protein depletion and re-feeding.", "content": "Concentration of elongation factor 2 in rat skeletal muscle during protein depletion and re-feeding. Rat skeletal-muscle elongation factor 2 was assayed by causing it to react with NAD(+) by using fragment A of diphtheria toxin as the catalyst. Dietary protein restriction decreased the concentration of elongation factor 2 in homogenates of whole muscle. These decreases paralleled a decline in muscle RNA so that the number of molecules of elongation factor 2 per ribosome appeared to be independent of the diet. We conclude that elongation factor 2 is probably not the factor limiting the rate of muscle protein synthesis and is not responsible for the fall in the protein-synthetic rate in vivo observed in the muscles of animals whose dietary protein intake is inadequate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374185"}
{"pmid": "4374191", "title": "The effect of energization on the apparent Michaelis-Mentne constant for oxygen in mitochondrial respiration.", "content": "The effect of energization on the apparent Michaelis-Mentne constant for oxygen in mitochondrial respiration. Lineweaver-Burk plots of 1/v against 1/[O(2)] for rat liver mitochondrial respiration with succinate or ascorbate+NNN'N'-tetramethyl-p-phenylenediamine as substrates are non-linear. In state 3u (uncoupled by trifluoromethoxycarbonyl cyanide phenylhydrazone) such plots tend to be concave upward, whereas in state 4 (energized) the plots were concave downward. The apparent K(m) for oxygen is larger in state 4 than in state 3u, despite the higher turnover in the latter system. It is postulated that at least one reversible reaction occurs between cytochrome c and cytochrome c oxidase, whose rate is increased on energization (reversed electron transfer); a model including such a reaction is proposed which accounts semiquantitatively for the observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374191"}
{"pmid": "4374186", "title": "Metabolism of dihydrotachysterol and 5,6-trans-cholecalciferol in the chick and the rat.", "content": "Metabolism of dihydrotachysterol and 5,6-trans-cholecalciferol in the chick and the rat. Dihydrotachysterol and 5,6-trans-cholecalciferol are biologically active analogues of cholecalciferol (vitamin D) with a similarity in steric structure to 1,25-dihydroxycholecalciferol, the active form of the vitamin. The question arises as to the nature of the active form of these analogues. High specific radioactivity (14)C- and (3)H-labelled forms of dihydrotachysterol and 5,6-trans-cholecalciferol and its 25-hydroxy derivative were synthesized and their metabolism was studied in chicks and rats. All these steroids were very rapidly metabolized compared with cholecalciferol; 20% of the dihydrotachysterol dose was excreted in bile in the first 24h, about 50% as a carboxylic acid derivative. Although polar metabolites were detected in tissues, no 1-hydroxy form was observed. Larger proportions of the parent steroid and its 25-hydroxy metabolite were detected in tissues compared with cholecalciferol, but no single metabolite was detected at the intracellular site of action of cholecalciferol. It is suggested that analogues of cholecalciferol will be biologically active if they possess a hydroxyl group in the same steric position as that at C-1 of cholecalciferol, with the greatest activity shown by those that also have a C-25 hydroxyl group. The implication of these findings for the chemical features necessary for binding to receptor proteins are briefly discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374186"}
{"pmid": "4374187", "title": "A new method for the preparation of uniformly 14C-labelled compounds by using Anacystis nidulans.", "content": "A new method for the preparation of uniformly 14C-labelled compounds by using Anacystis nidulans. 1. Growth conditions were devised which enabled Anacystis nidulans to be grown on high specific radioactivity (14)CO(2) (at over 98% isotopic abundance of (14)C) in a closed system with greater than 85% substrate utilization. 2. The DNA and RNA content of A. nidulans was estimated by various methods and compared with that of Chlorella pyrenoidosa. 3. A procedure was developed for the quantitative extraction and separation of the DNA and RNA from A. nidulans. 4. The fractionation and analysis of the DNA and RNA includes methods for the preparation of the uniformly (14)C-labelled deoxyribonucleoside monophosphates and the uniformly (14)C-labelled ribonucleoside monophosphates. 5. The base 6-methylaminopurine was identified as a component of the DNA. 6. The preparation and total yield of uniformly (14)C-labelled amino acids from A. nidulans are also briefly described. The results are discussed in relation to the use of other micro-organisms for the preparation of compounds labelled with (14)C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374187"}
{"pmid": "4374184", "title": "Role of cyclic adenosine 3':5'-monophosphate in the action of 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT)on hepatic and renal metabolism.", "content": "Role of cyclic adenosine 3':5'-monophosphate in the action of 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT)on hepatic and renal metabolism. The possibility whether alterations in the cyclic AMP-adenylate cyclase-phosphodiesterase system play a role in the action of 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT) on hepatic and renal carbohydrate metabolism was investigated. Administration of exogenous cyclic AMP (10mg/100g) was found to mimic the action of DDT which enhanced the activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase, fructose 1,6-diphosphatase and glucose 6-phosphatase in both liver and kidney cortex, elevated the concentration of blood glucose and urea and decreased the amount of hepatic glycogen. Treatment with theophylline augmented the effects of a submaximal dose of this halogenated hydrocarbon on serum urea and glucose as well as the key gluconeogenic enzymes in liver and kidney cortex. Addition of DDT in vitro to liver and kidney homogenates resulted in a significant enhancement of adenylate cyclase activity. Hepatic and renal slices from rats already treated with DDT displayed an increased ability to convert [(3)H]adenosine into cyclic [(3)H]AMP. Whereas kidney-cortex slices excised from rats given caffeine and DDT produced an even greater amount of cyclic [(3)H]AMP, imidazole, propranolol and hydrazine prevented the insecticide-stimulated rise in cyclic nucleotide production. In contrast, prostaglandin E(1) failed to exert any significant effect on DDT-induced increases in cyclic [(3)H]AMP synthesis from radioactive adenosine. The present study and our previous findings (Kacew & Singhal, 1973e) support the concept that the DDT-induced alterations in carbohydrate metabolism of liver and kidney cortex may be related to an initial stimulation of the cyclic AMP-adenylate cyclase system in these tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374184"}
{"pmid": "4374188", "title": "Properties of pyruvate dehydrogenase of rat mammary tissue and its changes during pregnancy, lactation and weaning.", "content": "Properties of pyruvate dehydrogenase of rat mammary tissue and its changes during pregnancy, lactation and weaning. Pyruvate dehydrogenase of rat mammary tissue showed many of the regulatory properties of the analogous enzyme in other mammalian tissues. It was inactivated in the presence of low concentrations of ATP and this rate of inactivation was slowed if pyruvate or PP(1) was also present. Reactivation by Mg(2+) in the presence of low concentrations of Ca(2+) occurred over a similar time-course. The K(m) value for Mg(2+) in this process was about 2mm. The enzyme was assayed in extracts of freeze-clamped mammary glands removed from pregnant, lactating or recently weaned rats under halothane anaesthesia. Both the initial activity and the activity after full activation (;total enzyme activity') were determined. The former parameter, when expressed on a DNA basis, varied within a range of 40 times its lowest value. Maximum total enzyme activity was about 1 unit/g wet wt. The total enzyme activity and the fraction in the active form increased in step from pregnancy to mid-lactation, remained elevated until the end of lactation and then fell steeply within 3 days after weaning. The correlation of these two parameters of enzyme activity may indicate a common regulatory factor or else an interdependence arising from inherent properties of the multi-enzyme complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374188"}
{"pmid": "4374190", "title": "Glycosyltransferases in the Golgi membranes of onion stem.", "content": "Glycosyltransferases in the Golgi membranes of onion stem. Cell fractions consisting largely of Golgi membranes were prepared from the meristematic region of the onion. Several enzyme activities were found to be localized in these fractions: inosine diphosphatase, galactosyltransferases and glucosyltransferases. The fractions catalysed the transfer of [(14)C]galactose from UDP-galactose to endogenous and cell-sap acceptors, to N-acetylglucosamine and to ovalbumin. In the presence of bovine alpha-lactalbumin, transfer to glucose (lactose synthesis) was catalysed. [(14)C]Glucose was transferred from UDP-glucose to endogenous and cell-sap acceptors, to cellobiose and to fructose (sucrose synthesis). All these activities were latent, being potentiated by detergents (Triton X-100 or sodium deoxycholate). The characteristics of some of these enzyme activities are described and their biological significance is discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374190"}
{"pmid": "4374195", "title": "The role of adenosine 3':5'-cyclic monophosphate in the division of WI 38 cells. The cellular response to prostaglandin E1 and the effects of an cyclic adenosine 3':5'-cyclic monophosphate analogue and prostaglandin E1 on cell division.", "content": "The role of adenosine 3':5'-cyclic monophosphate in the division of WI 38 cells. The cellular response to prostaglandin E1 and the effects of an cyclic adenosine 3':5'-cyclic monophosphate analogue and prostaglandin E1 on cell division. Inhibition of growth and DNA synthesis was observed in WI 38 cells incubated with 8-methylthioadenosine 3':5'-cyclic monophosphate or prostaglandin E(1). The effect of both compounds on cell growth was reversible. On removal of these compounds from culture media the cells initiated DNA synthesis and divided. In addition, prostaglandin E(1) stimulated cyclic AMP formation in these cells to over 40 times the normal basal value. The increase in cyclic AMP concentration in WI 38 cells after addition of prostaglandin E(1) showed a marked variation. Cells that had recently been treated with trypsin and plated at a lower cell density exhibited a smaller response to addition of prostaglandin E(1) than cells that had divided and reached confluence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374195"}
{"pmid": "4374189", "title": "The relationship between the concentration of adenosine 3':5'-cyclic monophosphate and the anti-lipolytic action of insulin in isolated rat fat-cells.", "content": "The relationship between the concentration of adenosine 3':5'-cyclic monophosphate and the anti-lipolytic action of insulin in isolated rat fat-cells. The relationship between cyclic AMP content and lipolysis, as measured by glycerol formation, was studied in isolated rat fat-cells. Inhibition of lipolysis by insulin in the presence of a low concentration of adrenaline was accompanied by little or no lowering of cyclic AMP content, measured after 15min incubation. The time-course of cyclic AMP content after addition of adrenaline showed that the effect of insulin in lowering cyclic AMP content measured after 2-5min was gradually lost over the next hour, mainly because of the fall in cyclic AMP content after an early peak in the presence of adrenaline alone. There was a 44% loss of immunoreactive insulin, from an initial concentration of 0.3nm, during a 1h incubation with fat-cells. Insulin did not affect partitioning of cyclic AMP between cells and incubation medium. When the correlation between cyclic AMP content and rate of lipolysis was investigated for a wide range of adrenaline concentrations, it was found that the lowering of cyclic AMP content by insulin was much less than that required to account for the amount of inhibition of lipolysis. It is concluded that inhibition of adrenaline-stimulated lipolysis by insulin involves factors in addition to a decrease in intracellular cyclic AMP concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374189"}
{"pmid": "4374197", "title": "Changes in intramitochondrial adenine nucleotides in blowfly flight-muscle mitochondria.", "content": "Changes in intramitochondrial adenine nucleotides in blowfly flight-muscle mitochondria. 1. With freshly isolated blowfly mitochondria 38% of the intramitochondrial adenine nucleotide was present as AMP. 2. On incubation with oxidizable substrates the AMP and ADP concentrations fell and that of ATP rose; with pyruvate together with proline the ATP concentration reached its maximum value at 6min; with glycerol phosphate the phosphorylation of endogenous nucleotide was more rapid. 3. Addition of the uncoupling agent carbonyl cyanide phenylhydrazone caused a rapid fall of ATP and a parallel rise in ADP, then ADP was converted into AMP. 4. This was in contrast with rat liver mitochondria endogenous AMP concentrations, which were always lower than those of blowfly mitochondria and changed little under different metabolic conditions. 5. Evidence is presented that adenylate kinase (EC 2.7.4.3) has a dual distribution in blowfly mitochondria, a part being located in the matrix space and a part in the space between the outer and inner mitochondrial membranes, as in liver and other mitochondria. 6. The possible regulatory role of changing AMP concentrations in the mitochondrial matrix was investigated. Partially purified pyruvate carboxylase (EC 6.4.1.1) and citrate synthase (EC 4.1.3.7) were inhibited 30% by 2mm-AMP, whereas pyruvate dehydrogenase (EC 1.2.4.1) was unaffected. 7. AMP activated the NAD(+)-linked isocitrate dehydrogenase (EC 1.1.1.41) activity of blowfly mitochondria in the absence of ADP, but in the presence of ADP, AMP caused inhibition. 8. It is suggested that AMP may exert a controlling effect on the oxidative activity of blowfly mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374197"}
{"pmid": "4374196", "title": "The action of local anaesthetics on lipolysis and on adenosine 3':5'-cyclic monophosphate content in isolated rat fat-cells.", "content": "The action of local anaesthetics on lipolysis and on adenosine 3':5'-cyclic monophosphate content in isolated rat fat-cells. 1. Local anaesthetics inhibited hormone-stimulated lipolysis in isolated rat fat-cells. The most potent anaesthetic was dibucaine, which inhibited adrenaline-stimulated lipolysis by 50% at a concentration of 0.16mm. 2. The amount of inhibition produced by a given concentration of anaesthetic was very similar with adrenaline, theophylline and dibutyryl cyclic AMP, at submaximal and maximal concentrations. 3. The inhibitory effect of dibucaine on lipolysis was apparent within 5 min and was constant over 1h. 4. Dibucaine inhibited basal, adrenaline-stimulated and insulin-stimulated glucose uptake at concentrations 6-10-fold higher than those inhibiting lipolysis. 5. The effects of dibucaine on lipolysis and glucose uptake were reversed after removal of anaesthetic and washing of cells. 6. Dibucaine further elevated the concentration of cyclic AMP in the presence of adrenaline or adrenaline plus theophylline. 7. Dibucaine had no effect on ATP content at concentrations causing 80% inhibition of lipolysis, but lowered ATP content at higher concentrations. 8. The relative potency of different local anaesthetics as inhibitors of hormone-stimulated lipolysis paralleled their potency as inhibitors of ion movements in other systems. 9. The possibility is discussed that Ca(2+) ions are involved in the regulation of lipolysis, and that local anaesthetics inhibit lipolysis by interfering with Ca(2+) translocation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374196"}
{"pmid": "4374193", "title": "Measurement of the dynamics of stimulation and inhibition of steroidogenesis in isolated rat adrenal cells by using column perfusion.", "content": "Measurement of the dynamics of stimulation and inhibition of steroidogenesis in isolated rat adrenal cells by using column perfusion. Isolated adrenal cells were perfused in a small column by using Bio-Gel polyacrylamide beads as an inert supporting matrix, and the time-course of the response to various stimuli was observed by measuring fluorogenic 11-hydroxycorticosteroids in the effluent. A small but significant response was observed 1 min after stimulation with physiological concentrations of ACTH (adrenocorticotrophin), but the response did not start to build up rapidly for 3-4min and eventually reached a plateau after 9-10min. A similar pattern of events was observed for the decay of the steroid output on removal of ACTH. ACTH analogues, including one with a long duration of action in vivo, were found to produce responses with similar kinetics. However, cyclic AMP caused a more rapid increase in steroidogenesis and its effects were more short-lived after withdrawal. If, as present evidence suggests, cyclic AMP is produced rapidly after ACTH stimulation the delayed build-up of the steroidogenic response to ACTH would indicate that cyclic AMP may not be the intracellular mediator. When inhibitors were applied during ACTH stimulation, aminoglutethimide, which blocks mitochondrial conversion of cholesterol into pregnenolone (3beta-hydroxypregn-5-en-20-one), caused a rapid fall in steroid output (1 min), whereas cycloheximide took longer to achieve its full effect. Nevertheless, the response had fallen by 50% in 2 min, indicating a much shorter half-life than that previously reported for the labile protein implicated in steroidogenesis. In addition the rapid response to cyclic AMP makes it unlikely that steroid production is induced as a result of initiation of protein synthesis. This suggests that the labile protein plays an obligatory but permissive role in the development of the response. Column perfusion has proved to be a simple technique which can readily yield accurate data on responses of cells to stimulants and inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374193"}
{"pmid": "4374198", "title": "Adaptive changes in the capacity of systems used for the synthesis of citrulline in rat liver mitochondria in response to high- and-low-protein diets.", "content": "Adaptive changes in the capacity of systems used for the synthesis of citrulline in rat liver mitochondria in response to high- and-low-protein diets. 1. Citrulline synthesis was measured in mitochondria from rats fed on a standard diet, a high-protein diet, or on glucose. 2. With NH(4)Cl as the nitrogen source the rate of citrulline synthesis was higher in mitochondria from rats fed on a high-protein diet than in those from rats fed on a standard diet. When rats were fed solely on glucose the rate of synthesis of citrulline from NH(4)Cl was very low. 3. With glutamate as the nitrogen source the relative rates of citrulline synthesis were much lower than when NH(4)Cl was present, but similar adaptive changes occurred. 4. The activity of the mitochondrial glutamate-transporting system increased two to three times on feeding rats on a high-protein diet, but the K(m) for glutamate was unchanged. 5. Adaptive changes in certain intramitochondrial enzymes were also measured. 6. The results were interpreted to indicate that when an excess of substrate was present, citrulline synthesis from NH(4)Cl was rate-limited by the intramitochondrial concentration of N-acetyl-glutamate, but citrulline synthesis from glutamate was rate-limited primarily by the activity of the glutamate-transporting system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374198"}
{"pmid": "4374194", "title": "Increase in pituitary adenosine 3':5'-cyclic monophosphate content and potentiation of growth-hormone release from heifer anterior pituitary slices incubated in the presence of 3-isobutyl-1-methylxanthine.", "content": "Increase in pituitary adenosine 3':5'-cyclic monophosphate content and potentiation of growth-hormone release from heifer anterior pituitary slices incubated in the presence of 3-isobutyl-1-methylxanthine. The release of growth hormone from heifer anterior pituitary slices and the cyclic AMP content of the slices were increased by the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine, both increases being related to inhibitor concentration over the range 0.1-1.0mm. Neither Ba(2+) (6.9 or 2.3mm), K(+) (72mm), nor p-chloromercuribenzoate (20mum) had any effect on pituitary cyclic AMP content over a 20min period. 3-Isobutyl-1-methylxanthine potentiated the release of growth hormone in response to Ba(2+) (2.3mm) and K(+) (24mm), but the degree of potentiation did not depend on inhibitor concentration in the same way as did tissue cyclic AMP content. 3-Isobutyl-1-methylxanthine decreased the concentration of K(+) required to give maximum stimulation of growth-hormone release, but did not significantly increase the maximum response to Ba(2+). Growth-hormone release in the presence of prostaglandin E(2) (1mum) was increased by 3-isobutyl-1-methylxanthine and was inhibited by the prostaglandin antagonist, 7-oxa-13-prostynoic acid, although this antagonist increased the pituitary cyclic AMP concentration and potentiated the prostaglandin E(2)-induced rise in cyclic AMP content. The stimulation of growth-hormone release by p-chloromercuribenzoate was not potentiated by 3-isobutyl-1-methylxanthine. The data suggest that Ba(+) and K(+) act at the same point in the secretory process as 3-isobutyl-1-methylxanthine, although by a different mechanism, and that p-chloromercuribenzoate has a different point of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374194"}
{"pmid": "4374192", "title": "Mode of inhibition of mitochondrial energy transduction by chlorophenoxyisobutyrate.", "content": "Mode of inhibition of mitochondrial energy transduction by chlorophenoxyisobutyrate. 1. alpha-p-Chlorophenoxyisobutyric acid, the ethyl ester of which is widely used as an antihypercholesterolaemic drug, is an inhibitor of energy-transfer reactions in isolated rat liver mitochondria. 2. The compound at lower concentrations (<4.0mumol/mg of mitochondrial protein) inhibits state 3 oxidation, stimulates state 4 oxidation, abolishes respiratory control and stimulates the latent adenosine triphosphatase activity of mitochondria. The inhibition imposed on state 3 oxidation is relieved by dinitrophenol. 3. At higher concentrations it inhibits coupled phosphorylation as well as dinitrophenol-stimulated adenosine triphosphatase activity. The inhibition of state 3 oxidation under these conditions is not reversed by uncouplers. 4. The three coupling sites of phosphorylation exhibit differential susceptibility to inactivation by this compound. Coupled phosphorylation at the first site is abolished at a drug concentration of 3.0mumol/mg of protein. The third site is inactivated when the concentration of the drug reaches 5.0mumol/mg of protein. The second site is the most refractory and drug concentrations of the order of 10.0mumol/mg of protein are required effectively to inhibit phosphorylation at this site. 5. The compound also inhibits ATP-dependent reversal of electron transport as well as the adenosine triphosphatase activity in submitochondrial particles. 6. The oxidation of NADH and succinate in these particles is not inhibited. 7. These properties indicate that the compound acts as an ;inhibitory uncoupler' of energy-transfer reactions in isolated mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374192"}
{"pmid": "4374202", "title": "Isolation of the coat proteins of foot-and-mouth disease virus and analysis of the composition and N-terminal endgroups.", "content": "Isolation of the coat proteins of foot-and-mouth disease virus and analysis of the composition and N-terminal endgroups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374202"}
{"pmid": "4374203", "title": "The immobilization of glucose oxidase via activation of its carbohydrate residues.", "content": "The immobilization of glucose oxidase via activation of its carbohydrate residues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374203"}
{"pmid": "4374179", "title": "The latent herpes simplex virus.", "content": "The latent herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374179"}
{"pmid": "4374199", "title": "The effects of potassium, 5-hydrocytryptamine, adrenocorticotrophin and angiotensin II on the concentration of adenosine 3':5'-cyclic monophosphate in suspensions of dispersed rat adrenal zona glomerulosa and zona fasciculata cells.", "content": "The effects of potassium, 5-hydrocytryptamine, adrenocorticotrophin and angiotensin II on the concentration of adenosine 3':5'-cyclic monophosphate in suspensions of dispersed rat adrenal zona glomerulosa and zona fasciculata cells. Dispersed rat adrenal cells prepared from both the capsule and the decapsulated gland were used to investigate the effects on cyclic AMP accumulation of known stimuli of steroidogenesis [ACTH (adrenocorticotrophin), angiotensin II, K(+) ions and 5-hydroxytryptamine]. Since glomerulosa-cell preparations from capsular strippings are normally contaminated with a proportion of fasciculata cells, cells purified by fractionation on a bovine serum albumin gradient were also used. The results showed that: (1) ACTH and angiotensin II stimulated cyclic AMP accumulation in both fractionated and unfractionated zona fasciculata cells; (2) 5-hydroxytryptamine and an increased extracellular K(+) concentration (from 3.6 to 8.4mm) had no effect on cyclic AMP concentrations in fasciculata cell preparations; (3) the addition of ACTH, angiotensin II, 5-hydroxytryptamine or K(+) to the incubation medium resulted in increased cyclic AMP concentrations in unpurified zona glomerulosa cell preparations; (4) fractionation and hence the virtual elimination of fasciculata contamination, did not affect the response to 5-hydroxytryptamine and increased K(+) concentration. However, the responses to ACTH and angiotensin II were markedly lowered but not abolished. These results strongly suggest a link between cyclic AMP production and steroidogenesis in the zone of the adrenal gland that specifically secretes aldosterone. All four agents used stimulated both steroid output and cyclic AMP accumulation. However, at certain doses of 5-hydroxytryptamine, K(+) and angiotensin II the significant increases in corticosterone output were not accompanied by measurable increases in cyclic AMP accumulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374199"}
{"pmid": "4374201", "title": "Seven lysine isoaccepting tRNA's from polyoma virus-transformed cells.", "content": "Seven lysine isoaccepting tRNA's from polyoma virus-transformed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374201"}
{"pmid": "4374204", "title": "Binding of 1-norepinephrine to isolated rat fat cell plasma membranes. Evidence against covalent binding and binding to catechol-O-methyl transferase.", "content": "Binding of 1-norepinephrine to isolated rat fat cell plasma membranes. Evidence against covalent binding and binding to catechol-O-methyl transferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374204"}
{"pmid": "4374200", "title": "Synthesis of polyprenyltolouquinols from homogentisate and polyprenyl pyrophosphates in particulate fractions of Euglena and sugar beet.", "content": "Synthesis of polyprenyltolouquinols from homogentisate and polyprenyl pyrophosphates in particulate fractions of Euglena and sugar beet. Chloroplast-rich particles of sugar beet and Euglena gracilis are able to carry out the light-, H(2)O(2)- and O(2)-independent syntheses of a nonaprenyltoluquinol, an octaprenyltoluquinol and a phytyltoluquinol from homogentisate and nonaprenyl, octaprenyl and phytyl pyrophosphate. The formation of these compounds probably takes place by the concomitant polyprenylation (or phytylation) and non-oxidative decarboxylation of homogentisate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374200"}
{"pmid": "4374206", "title": "Heme complexes of rabbit hemopexin, human hemopexin and human serum albumin:  electron spin resonance and Mssbauer spectroscopic studies.", "content": "Heme complexes of rabbit hemopexin, human hemopexin and human serum albumin:  electron spin resonance and Mssbauer spectroscopic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374206"}
{"pmid": "4374205", "title": "The utility of infrared spectroscopy as a probe of intact tissue:  determination of carbon monoxide and hemeproteins in blood and heart muscle.", "content": "The utility of infrared spectroscopy as a probe of intact tissue:  determination of carbon monoxide and hemeproteins in blood and heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374205"}
{"pmid": "4374208", "title": "Phospholipid activation of Lactobacillus plantarum undecaprenyl pyrophosphate synthetase.", "content": "Phospholipid activation of Lactobacillus plantarum undecaprenyl pyrophosphate synthetase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374208"}
{"pmid": "4374207", "title": "Purification of exonuclease (phosphodiesterase) from the venom of Crotalus adamanteus.", "content": "Purification of exonuclease (phosphodiesterase) from the venom of Crotalus adamanteus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374207"}
{"pmid": "4374209", "title": "Binding of 5S estradiol receptor to poly-deoxynucleotides.", "content": "Binding of 5S estradiol receptor to poly-deoxynucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374209"}
{"pmid": "4374210", "title": "Stimulation of guanosine 3',5'-cyclic monophosphate accumulation in rat anterior pituitary gland in vitro by synthetic somatostatin.", "content": "Stimulation of guanosine 3',5'-cyclic monophosphate accumulation in rat anterior pituitary gland in vitro by synthetic somatostatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374210"}
{"pmid": "4374212", "title": "Enzyme activated anti-tumour agents. Conjugates of p-hydroxyaniline mustard as substrates for hydrolytic enzymes.", "content": "Enzyme activated anti-tumour agents. Conjugates of p-hydroxyaniline mustard as substrates for hydrolytic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374212"}
{"pmid": "4374214", "title": "Inhibition of DNA polymerases from RNA tumor viruses by tilorone and congeners: site of action.", "content": "Inhibition of DNA polymerases from RNA tumor viruses by tilorone and congeners: site of action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374214"}
{"pmid": "4374213", "title": "Inhibition of cell growth and of purine biosynthesis by allopurinol and 4-aminopyrazolo(3,4-d)pyrimidine--a comparative study.", "content": "Inhibition of cell growth and of purine biosynthesis by allopurinol and 4-aminopyrazolo(3,4-d)pyrimidine--a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374213"}
{"pmid": "4374216", "title": "Stimulated chloride transport by isolated parietal cells.", "content": "Stimulated chloride transport by isolated parietal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374216"}
{"pmid": "4374215", "title": "Inhibition of platelet aggregation by 2-(p-chlorophenyl)-4-thiazoleacrylic acid (Wy-23,049)--comparison with acetylsalicylic acid.", "content": "Inhibition of platelet aggregation by 2-(p-chlorophenyl)-4-thiazoleacrylic acid (Wy-23,049)--comparison with acetylsalicylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374215"}
{"pmid": "4374219", "title": "The effects of catecholamines upon the metabolism of foreign compounds and upon the distribution of perfusate in the isolated liver of the rat.", "content": "The effects of catecholamines upon the metabolism of foreign compounds and upon the distribution of perfusate in the isolated liver of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374219"}
{"pmid": "4374217", "title": "Effect of alphaxalone, a new intravenous anaesthetic, on oxidative phosphorylation in rabbit brain mitochondria.", "content": "Effect of alphaxalone, a new intravenous anaesthetic, on oxidative phosphorylation in rabbit brain mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374217"}
{"pmid": "4374218", "title": "Further studies concerning the effects of clofibrate on respiration and oxidative phosphorylation of rat liver mitochondria.", "content": "Further studies concerning the effects of clofibrate on respiration and oxidative phosphorylation of rat liver mitochondria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374218"}
{"pmid": "4374220", "title": "Inhibition of some rat hepatic microsomal enzymes by ethoxyquin.", "content": "Inhibition of some rat hepatic microsomal enzymes by ethoxyquin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374220"}
{"pmid": "4374225", "title": "Occult carcinoma of the breast.", "content": "Occult carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374225"}
{"pmid": "4374224", "title": "Usefulness and limitations of circumferential fibre shortening velocity in evaluating segmental disorders of left ventricular contraction.", "content": "Usefulness and limitations of circumferential fibre shortening velocity in evaluating segmental disorders of left ventricular contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374224"}
{"pmid": "4374226", "title": "Cell mediated immunity to herpesvirus type 1 in carcinoma and pre-cancerous lesions.", "content": "Cell mediated immunity to herpesvirus type 1 in carcinoma and pre-cancerous lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374226"}
{"pmid": "4374227", "title": "Evaluation of host immunity in human neoplasia. II. Discussion.", "content": "Evaluation of host immunity in human neoplasia. II. Discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374227"}
{"pmid": "4374228", "title": "HL-A antigens and malignant disease.", "content": "HL-A antigens and malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374228"}
{"pmid": "4374229", "title": "Immunological aspects of trophoblastic neoplasia.", "content": "Immunological aspects of trophoblastic neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374229"}
{"pmid": "4374230", "title": "Immunity to tumours of the murine leukaemia-sarcoma virus complex.", "content": "Immunity to tumours of the murine leukaemia-sarcoma virus complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374230"}
{"pmid": "4374232", "title": "The management of the palatal pleomorphic adenoma.", "content": "The management of the palatal pleomorphic adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374232"}
{"pmid": "4374231", "title": "Significance of serum factors modifying cellular immune responses to growing tumours.", "content": "Significance of serum factors modifying cellular immune responses to growing tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374231"}
{"pmid": "4374233", "title": "An unusual presentation of rhabdomyosarcoma: a case report.", "content": "An unusual presentation of rhabdomyosarcoma: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374233"}
{"pmid": "4374234", "title": "Transport of nucleosides, nucleic acid bases, choline and glucose by animal cells in culture.", "content": "Transport of nucleosides, nucleic acid bases, choline and glucose by animal cells in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374234"}
{"pmid": "4374235", "title": "Organisation of proteins in membranes with special reference to the cytochrome oxidase system.", "content": "Organisation of proteins in membranes with special reference to the cytochrome oxidase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374235"}
{"pmid": "4374237", "title": "The application of immobilized NAD+ in an enzyme electrode and in model enzyme reactors.", "content": "The application of immobilized NAD+ in an enzyme electrode and in model enzyme reactors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374237"}
{"pmid": "4374236", "title": "Cytochrome c binding to enzymes and membranes.", "content": "Cytochrome c binding to enzymes and membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374236"}
{"pmid": "4374238", "title": "Acrylic copolymers as matrices for the immobilization of enzymes. II. The effect of a hydrophobic microenvironment on enzyme reactions studied with alcohol dehydrogenase immobilized to different acrylic copolymers.", "content": "Acrylic copolymers as matrices for the immobilization of enzymes. II. The effect of a hydrophobic microenvironment on enzyme reactions studied with alcohol dehydrogenase immobilized to different acrylic copolymers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374238"}
{"pmid": "4374239", "title": "Stereochemistry of the L-iditol dehydrogenase catalyzed hydrogen transfer to NAD.", "content": "Stereochemistry of the L-iditol dehydrogenase catalyzed hydrogen transfer to NAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374239"}
{"pmid": "4374240", "title": "Hepatic sulfite oxidase. Effect of anions on interaction with cytochrome c.", "content": "Hepatic sulfite oxidase. Effect of anions on interaction with cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374240"}
{"pmid": "4374241", "title": "Hepatic sulfite oxidase. Identification of the molybdenum center as the site of irreversible inactivation by ferricyanide.", "content": "Hepatic sulfite oxidase. Identification of the molybdenum center as the site of irreversible inactivation by ferricyanide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374241"}
{"pmid": "4374242", "title": "Glycogen synthesis in mouse Ehrlich ascites carcinoma cells. The presence of an endogenous inhibitor for activation of glycogen synthase.", "content": "Glycogen synthesis in mouse Ehrlich ascites carcinoma cells. The presence of an endogenous inhibitor for activation of glycogen synthase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374242"}
{"pmid": "4374244", "title": "O-phosphoserine phosphatase from bovine brain and kidney. High molecular weight forms occurring during the purification.", "content": "O-phosphoserine phosphatase from bovine brain and kidney. High molecular weight forms occurring during the purification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374244"}
{"pmid": "4374245", "title": "Studies on cyclic AMP phosphodiesterase in sea urchin eggs.", "content": "Studies on cyclic AMP phosphodiesterase in sea urchin eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374245"}
{"pmid": "4374243", "title": "Histone kinases and cyclic AMP-binding capacity of nuclei of human tonsillar lymphocytes.", "content": "Histone kinases and cyclic AMP-binding capacity of nuclei of human tonsillar lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374243"}
{"pmid": "4374246", "title": "Inorganic pyrophosphatase in cultured cells.", "content": "Inorganic pyrophosphatase in cultured cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374246"}
{"pmid": "4374247", "title": "Rat pancreas adenylate cyclase. II. Inactivation and protection of its hormone receptor sites.", "content": "Rat pancreas adenylate cyclase. II. Inactivation and protection of its hormone receptor sites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374247"}
{"pmid": "4374261", "title": "Sleep and eye movement patterns in two groups of retardates.", "content": "Sleep and eye movement patterns in two groups of retardates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374261"}
{"pmid": "4374262", "title": "Intramitonchondrial crystalline inclusions in metastatic hypernephroma of the liver.", "content": "Intramitonchondrial crystalline inclusions in metastatic hypernephroma of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374262"}
{"pmid": "4374263", "title": "Influence of glucagon on canalicular bile production in the dog.", "content": "Influence of glucagon on canalicular bile production in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374263"}
{"pmid": "4374265", "title": "Urinary cyclic AMP as an aid in the differential diagnosis of hypercalcemia.", "content": "Urinary cyclic AMP as an aid in the differential diagnosis of hypercalcemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374265"}
{"pmid": "4374264", "title": "Nasopharyngeal carcinoma. VII. B and T lymphocytes in the circulating blood and in tumour tissue.", "content": "Nasopharyngeal carcinoma. VII. B and T lymphocytes in the circulating blood and in tumour tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374264"}
{"pmid": "4374267", "title": "Evaluation of bilirubin derivatives for mass spectral analysis.", "content": "Evaluation of bilirubin derivatives for mass spectral analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374267"}
{"pmid": "4374268", "title": "Large scale enzymatic synthesis of nucleoside-5'-monophosphates using a phosphotransferase from carrots.", "content": "Large scale enzymatic synthesis of nucleoside-5'-monophosphates using a phosphotransferase from carrots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374268"}
{"pmid": "4374272", "title": "Effect of shock following prolonged crushing of soft tissues on hypothalamic-pituitary-adrenal function.", "content": "Effect of shock following prolonged crushing of soft tissues on hypothalamic-pituitary-adrenal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374272"}
{"pmid": "4374273", "title": "Effect of sucrose on lipid metabolism in experimental animals and its relation to the fat content of their diet.", "content": "Effect of sucrose on lipid metabolism in experimental animals and its relation to the fat content of their diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374273"}
{"pmid": "4374274", "title": "Action of cardiac glycosides on the concentrations of adenyl nucleotides and nicotinamide-adenine dinucleotides in the rat myocardium.", "content": "Action of cardiac glycosides on the concentrations of adenyl nucleotides and nicotinamide-adenine dinucleotides in the rat myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374274"}
{"pmid": "4374275", "title": "Intraendothelial inclusions in systemic lupus erythematosus.", "content": "Intraendothelial inclusions in systemic lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374275"}
{"pmid": "4374276", "title": "Effect of exogenous cytochrome C on oxidative phosphorylation in the liver of rats with acute toxic hepatitis.", "content": "Effect of exogenous cytochrome C on oxidative phosphorylation in the liver of rats with acute toxic hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374276"}
{"pmid": "4374277", "title": "Ultrastructural localization of NAD-pyrophosphorylase in mouse liver nuclei.", "content": "Ultrastructural localization of NAD-pyrophosphorylase in mouse liver nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374277"}
{"pmid": "4374278", "title": "Electroendosmosis correction for electrophoretic mobility determined in cells.", "content": "Electroendosmosis correction for electrophoretic mobility determined in cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374278"}
{"pmid": "4374280", "title": "The use of 3-acetyl-pyridine adenine dinucleotide in the spectrophotometric assay of enzymatic activities coupled to dehydrogenases of unfavorable equilibrium.", "content": "The use of 3-acetyl-pyridine adenine dinucleotide in the spectrophotometric assay of enzymatic activities coupled to dehydrogenases of unfavorable equilibrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374280"}
{"pmid": "4374279", "title": "Rapid assays for adenylate cyclase and 3',5' cyclic AMP phosphodiesterase activities. Simultaneous measurements of other pathways of ATP catabolism.", "content": "Rapid assays for adenylate cyclase and 3',5' cyclic AMP phosphodiesterase activities. Simultaneous measurements of other pathways of ATP catabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374279"}
{"pmid": "4374281", "title": "Thin layer gel filtration as a method for routine steroid receptor binding studies.", "content": "Thin layer gel filtration as a method for routine steroid receptor binding studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374281"}
{"pmid": "4374282", "title": "In vivo preparation of (32P) adenosine 3',5'-cyclic monophosphate.", "content": "In vivo preparation of (32P) adenosine 3',5'-cyclic monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374282"}
{"pmid": "4374283", "title": "A simple and highly sensitive method for sequence determination of 32P-labeled oligonucleotides.", "content": "A simple and highly sensitive method for sequence determination of 32P-labeled oligonucleotides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374283"}
{"pmid": "4374284", "title": "Effect of pharmacological blockade on lithium-induced water drinking.", "content": "Effect of pharmacological blockade on lithium-induced water drinking. Administration of lithium chloride (40 mg/kg i.p.) led to a significant increase in 24 h water intake of rats. Prior administration of propranolol and haloperidol blocked the effect of lithium while atropine failed to show such an effect. The dipsogenic effect of lithium is probably exerted through beta-adrenergic and dopaminergic pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374284"}
{"pmid": "4374285", "title": "Proceedings: Influence of postaglandins and oestrus cycle on the spasmodic action of angiotensin II and oxytocin on rat uterus.", "content": "Proceedings: Influence of postaglandins and oestrus cycle on the spasmodic action of angiotensin II and oxytocin on rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374285"}
{"pmid": "4374286", "title": "Proceedings: Oestradiol binding in neonatal rat brain cytosol.", "content": "Proceedings: Oestradiol binding in neonatal rat brain cytosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374286"}
{"pmid": "4374288", "title": "A study of the metabolic requirements for the contractile action of angiotensin upon guinea-pig ileum.", "content": "A study of the metabolic requirements for the contractile action of angiotensin upon guinea-pig ileum. 1 Acetylcholine and angiotensin elicit a contraction of guinea-pig ileum. The metabolic requirements for these actions have been investigated.2 The angiotensin-induced response was far more dependent upon the presence of glucose than was the response to acetylcholine.3 Anoxia and oxidative enzyme inhibition preferentially reduced the angiotensin-induced response.4 The significance of these results is discussed. It is concluded that the response to angiotensin is dependent upon an ATP source distinct from that required by the contractile process. It is further shown that this energy-dependent stage cannot be identified with the indirect, cholinergic component of the angiotensin response in this tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374288"}
{"pmid": "4374287", "title": "Proceedings: The effect of tetraethylammonium (TEA) on the anococcygeus muscle and on its response to motor and to inhibitory nerve stimulation.", "content": "Proceedings: The effect of tetraethylammonium (TEA) on the anococcygeus muscle and on its response to motor and to inhibitory nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374287"}
{"pmid": "4374289", "title": "Long-term infusion of growth hormone release inhibiting hormone in acromegaly: effects on pituitary and pancreatic hormones.", "content": "Long-term infusion of growth hormone release inhibiting hormone in acromegaly: effects on pituitary and pancreatic hormones. Growth hormone release inhibiting hormone (GH-RIH) was infused at a rate of 1.3 mug/min for 28 hours into four patients with acromegaly, two of whom also had clinical diabetes mellitus. Growth hormone and glucagon were suppressed throughout the infusion though delayed secretion of insulin occurred in association with both meals and an oral glucose load. Glucose tolerance was improved in one diabetic patient who was taking chlorpropamide while the other required much less insulin than usual. Secretion of endogenous thyroid-stimulating hormone was lowered in one euthyroid patient on carbimazole. Luteinizing hormone, follicle-stimulating hormone, ACTH, and prolactin were not affected. Serum somatomedin levels were reduced in one patient. There was a rapid rebound of all the suppressed hormones when the infusions stopped. Longer-acting analogues of GH-RIH will be needed before long-term therapy of acromegaly or diabetes mellitus becomes possible, but such preparations should be available soon for clinical trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374289"}
{"pmid": "4374291", "title": "Letter: neuropathy due to cytosine arabinoside.", "content": "Letter: neuropathy due to cytosine arabinoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374291"}
{"pmid": "4374290", "title": "Blood and neoplastic diseases. Management of solid tumours-surgery, radiotherapy, and chemotherapy.", "content": "Blood and neoplastic diseases. Management of solid tumours-surgery, radiotherapy, and chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374290"}
{"pmid": "4374292", "title": "Blood and neoplastic diseases. Solid tumours in children.", "content": "Blood and neoplastic diseases. Solid tumours in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374292"}
{"pmid": "4374293", "title": "Food intake and amphetamine anorexia after selective forebrain norepinephrine loss.", "content": "Food intake and amphetamine anorexia after selective forebrain norepinephrine loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374293"}
{"pmid": "4374294", "title": "Changes in the activity of respiratory neurons during sleep.", "content": "Changes in the activity of respiratory neurons during sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374294"}
{"pmid": "4374295", "title": "Multiple sites of spike initiation in a single dendritic system.", "content": "Multiple sites of spike initiation in a single dendritic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374295"}
{"pmid": "4374296", "title": "The effect of diethyl ester L-glutamate on evoked excitatory junction potentials at the crustacean neuromuscular junction.", "content": "The effect of diethyl ester L-glutamate on evoked excitatory junction potentials at the crustacean neuromuscular junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374296"}
{"pmid": "4374297", "title": "5-Hydroxydopamine 'tagged' neuronal boutons in rabbit neostriatum: interrelationship between vesicles and axonal membrane.", "content": "5-Hydroxydopamine 'tagged' neuronal boutons in rabbit neostriatum: interrelationship between vesicles and axonal membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374297"}
{"pmid": "4374298", "title": "The origin of the dopamine nerve terminals in limbic and frontal cortex. Evidence for meso-cortico dopamine neurons.", "content": "The origin of the dopamine nerve terminals in limbic and frontal cortex. Evidence for meso-cortico dopamine neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374298"}
{"pmid": "4374302", "title": "The reliability of selective media for the enumeration of unheated and heated staphylococci.", "content": "The reliability of selective media for the enumeration of unheated and heated staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374302"}
{"pmid": "4374303", "title": "Does hypolipidemic therapy prevent coronary heart disease?", "content": "Does hypolipidemic therapy prevent coronary heart disease?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374303"}
{"pmid": "4374305", "title": "The ultrastructure of the human fetal pineal gland. I. Cell types and blood vessels.", "content": "The ultrastructure of the human fetal pineal gland. I. Cell types and blood vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374305"}
{"pmid": "4374304", "title": "Ultrastructural studies on the development of the nerve supply in the rabbit pars intermedia.", "content": "Ultrastructural studies on the development of the nerve supply in the rabbit pars intermedia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374304"}
{"pmid": "4374306", "title": "Morphometric analysis of the midgut of female Aedes aegypti (L.) (Insecta, Diptera) under various physiological conditions.", "content": "Morphometric analysis of the midgut of female Aedes aegypti (L.) (Insecta, Diptera) under various physiological conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374306"}
{"pmid": "4374307", "title": "Ovulation and the mechanism of follicle rupture. IV. Ultrastructure of membrana granulosa of rabbit graafian follicles prior to induced ovulation.", "content": "Ovulation and the mechanism of follicle rupture. IV. Ultrastructure of membrana granulosa of rabbit graafian follicles prior to induced ovulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374307"}
{"pmid": "4374308", "title": "Catalase-like crystals in parathyroid gland cells of Rana temporaria L.", "content": "Catalase-like crystals in parathyroid gland cells of Rana temporaria L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374308"}
{"pmid": "4374310", "title": "The fine structure of prostomial photoreceptors in Eulalia viridis (Polychaeta; Annelida).", "content": "The fine structure of prostomial photoreceptors in Eulalia viridis (Polychaeta; Annelida).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374310"}
{"pmid": "4374309", "title": "Effects of ACTH on organelle interrelationships in the corpus luteum of the pregnant deermouse.", "content": "Effects of ACTH on organelle interrelationships in the corpus luteum of the pregnant deermouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374309"}
{"pmid": "4374311", "title": "Cytologic observations on the secretory cells of the chin (submandibular) gland and brown inguinal gland in the rabbit.", "content": "Cytologic observations on the secretory cells of the chin (submandibular) gland and brown inguinal gland in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374311"}
{"pmid": "4374312", "title": "Primary tissue culture of human adult adrencortical cells. Methodology and electron microscopic observations on ACTH-deprived and ACTH-treated cortical cells.", "content": "Primary tissue culture of human adult adrencortical cells. Methodology and electron microscopic observations on ACTH-deprived and ACTH-treated cortical cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374312"}
{"pmid": "4374313", "title": "An ultrastructural and electrophysiological study of the development of neuro-muscular junctions between previously dissociated foetal rat cells in vitro.", "content": "An ultrastructural and electrophysiological study of the development of neuro-muscular junctions between previously dissociated foetal rat cells in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374313"}
{"pmid": "4374314", "title": "In vitro synthesis of methylated messenger RNA by the virion-associated RNA polymerase of vesicular stomatitis virus.", "content": "In vitro synthesis of methylated messenger RNA by the virion-associated RNA polymerase of vesicular stomatitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374314"}
{"pmid": "4374315", "title": "Alterations leading to increased ribonucleotide reductase in cells selected for resistance to deoxynucleosides.", "content": "Alterations leading to increased ribonucleotide reductase in cells selected for resistance to deoxynucleosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374315"}
{"pmid": "4374316", "title": "The effect of cyclic nucleotides on purine biosynthesis and the induction of PRPP synthetase during lymphocyte activation.", "content": "The effect of cyclic nucleotides on purine biosynthesis and the induction of PRPP synthetase during lymphocyte activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374316"}
{"pmid": "4374319", "title": "Increased urinary excretion of pyrimidine and nicotinamide derivatives in rats treated with methyl methanesulphonate.", "content": "Increased urinary excretion of pyrimidine and nicotinamide derivatives in rats treated with methyl methanesulphonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374319"}
{"pmid": "4374320", "title": "Specificity and inhibition of an amylase present in the testicular tissue of the rat.", "content": "Specificity and inhibition of an amylase present in the testicular tissue of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374320"}
{"pmid": "4374318", "title": "Repair replication of opossum lymphocyte DNA: effect of compounds that bind to DNA.", "content": "Repair replication of opossum lymphocyte DNA: effect of compounds that bind to DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374318"}
{"pmid": "4374321", "title": "Evaluation of the precipitation-in-gel reaction in the diagnosis of smallpox.", "content": "Evaluation of the precipitation-in-gel reaction in the diagnosis of smallpox. Specimens of vesicular or pustular fluids and of scabs from patients with smallpox as well as emulsions of variola-infected chorioallantoic membrane (CAM) were tested for virus titres and by the precipitation-in-gel (PIG) reaction. They were also tested after exposing them directly to sunlight and after keeping them at temperatures of -20 degrees C, 4 degrees C, and 25 degrees C. It was found that when extracts of fresh specimens were diluted to the point where the PIG reaction became negative there was still a titre of 10(4)-10(5) infectivity in the swab extracts and 10(3)-10(4) infectivity in the scab extracts. It was also found that the PIG reactions were all negative on specimens that were kept for 14 days at 25 degrees C, and that several were negative after only 7 days; the loss in infectivity titre, however, was only slight in all the specimens tested. It is concluded that the laboratory diagnosis of smallpox by virus inoculation of CAM is more reliable than by the PIG test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374321"}
{"pmid": "4374322", "title": "Transmission of the virus of foot and mouth disease between animals and man.", "content": "Transmission of the virus of foot and mouth disease between animals and man. The virus of foot and mouth disease causes severe epizootics in animals and infrequently evokes painful, but transient, clinical signs in man. Adults in certain occupational groups and young children are particularly exposed to risk. Infected persons may disseminate virus for up to about 14 days. The virus can be transmitted from animals to animals, from animals to man, from man to animals and, probably, from man to man. Evidence for transfer of the disease between human and animal populations is reviewed in detail and modern methods of diagnosis are described. Predisposing factors play an important role in the development of overt foot and mouth disease in man. Subclinical infection occurs. The possibility of aerial transfer of the virus between man and domestic livestock constitutes a hazard, especially to the latter. Attention is directed to the need for sophisticated diagnostic techniques, to requirements for adequate precautions in the handling and disposal of affected animals, and to hygienic measures for disease control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374322"}
{"pmid": "4374331", "title": "Rehabilitation of the cancer patient: its role in the scheme of comprehensive care.", "content": "Rehabilitation of the cancer patient: its role in the scheme of comprehensive care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374331"}
{"pmid": "4374332", "title": "Editorial: the current status of feline leukemia virus research.", "content": "Editorial: the current status of feline leukemia virus research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374332"}
{"pmid": "4374333", "title": "Simple siliceous pneumoconiosis of Bedouin females in the Negev desert.", "content": "Simple siliceous pneumoconiosis of Bedouin females in the Negev desert.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374333"}
{"pmid": "4374334", "title": "Determination of drugs in biologic specimens--a review.", "content": "Determination of drugs in biologic specimens--a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374334"}
{"pmid": "4374336", "title": "Computer programs for ESR spectral analysis.", "content": "Computer programs for ESR spectral analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374336"}
{"pmid": "4374337", "title": "Adrenal function in patients receiving medroxyprogesterone acetate.", "content": "Adrenal function in patients receiving medroxyprogesterone acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374337"}
{"pmid": "4374338", "title": "Investigations on the use of testosterone oenanthate as a male contraceptive agent.", "content": "Investigations on the use of testosterone oenanthate as a male contraceptive agent. The effect of exogenous testosterone on male gonadal function was in vestigated by applying a practical dose schedule of weekly injections of testosterone enanthate.  7 healthy young males received 22 intramuscular injections of 250 mg testosterone enanthate once a week for a period of 21 weeks.  Mean sperm counts were reduced from a pretreatment value of 73 million sperm/ml to below 3 million sperm/ml within 9 weeks of testosterone administration and remained so during the whole treatment period.  A marked recovery of spermatogenesis did not occur before 13 weeks after testosterone withdrawal, when the mean sperm count rose to 63 million sperm/ml.  Changes of the mean sperm motility and percentage of normal sperm morphology generally paralleled those of the mean sperm concentration, whereas the mean semen volume, libido, potency, and secondary sex characteristics remained unaffected.  A consistently azoospermic semen was not developed by any individual.  This and the fact that sperm counts in 3 out of 7 males still showed some depression of spermatogenesis at the end of the observation period of 28 weeks after testosterone withdrawal indicate that testosterone enanthate admin istered in the  described dose schedule is not a safe male contraceptive agent.  However, further research on the use of hormones for the control of fertility in men seems warranted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374338"}
{"pmid": "4374340", "title": "Histopathology and histochemistry of the insects treated with chemosterilants. V. Nucleic acids, phospholipids and phosphatases in the female reproductive organs of chemosterilized Poecilocerus pictus.", "content": "Histopathology and histochemistry of the insects treated with chemosterilants. V. Nucleic acids, phospholipids and phosphatases in the female reproductive organs of chemosterilized Poecilocerus pictus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374340"}
{"pmid": "4374339", "title": "Ligand-induced oligomerization and regulatory mechanism.", "content": "Ligand-induced oligomerization and regulatory mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374339"}
{"pmid": "4374341", "title": "Antiviral 1,3,4-thiadiazoles. I. Action on multiplication of Mengo Virus in FL cells.", "content": "Antiviral 1,3,4-thiadiazoles. I. Action on multiplication of Mengo Virus in FL cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374341"}
{"pmid": "4374350", "title": "New data on three types of anahormones (anahormones of LH, GH, ACTH, lipotropin, calcitonin and parathyroid hormone).", "content": "New data on three types of anahormones (anahormones of LH, GH, ACTH, lipotropin, calcitonin and parathyroid hormone).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374350"}
{"pmid": "4374351", "title": "Phospholipid metabolism in embryonic rat fibroblasts following stimulation by a combination of the serum proteins S1 and S2.", "content": "Phospholipid metabolism in embryonic rat fibroblasts following stimulation by a combination of the serum proteins S1 and S2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374351"}
{"pmid": "4374352", "title": "Molecular morphology of ribosomes. Structural considerations of Escherichia coli ribosomal subunits utilizing lactoperoxidase-catalyzed iodination of ribosomal proteins.", "content": "Molecular morphology of ribosomes. Structural considerations of Escherichia coli ribosomal subunits utilizing lactoperoxidase-catalyzed iodination of ribosomal proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374352"}
{"pmid": "4374353", "title": "Nitrate reductase as a product-inducible enzyme.", "content": "Nitrate reductase as a product-inducible enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374353"}
{"pmid": "4374354", "title": "On the structure of phenylalanine tRNA from yeast. Spin-label studies.", "content": "On the structure of phenylalanine tRNA from yeast. Spin-label studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374354"}
{"pmid": "4374355", "title": "Precursors of cytochrome oxidase in cytochrome-oxidase-deficient cells of Neurospora crassa. Comparison of the nuclear mutant cni-1, the cytoplasmic mutant mi-1, and copper-depleted wild type.", "content": "Precursors of cytochrome oxidase in cytochrome-oxidase-deficient cells of Neurospora crassa. Comparison of the nuclear mutant cni-1, the cytoplasmic mutant mi-1, and copper-depleted wild type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374355"}
{"pmid": "4374356", "title": "Dose-limiting tissues in relation to types and location of tumours: implications for efforts to improve radiation dose distributions.", "content": "Dose-limiting tissues in relation to types and location of tumours: implications for efforts to improve radiation dose distributions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374356"}
{"pmid": "4374359", "title": "The influence of body weight and cell size on lipogenesis and lipolysis of isolated rat fat cells.", "content": "The influence of body weight and cell size on lipogenesis and lipolysis of isolated rat fat cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374359"}
{"pmid": "4374361", "title": "Effects of papaverine on the rabbit ileum under the influence of altered temperature and extracellular Ca2+.", "content": "Effects of papaverine on the rabbit ileum under the influence of altered temperature and extracellular Ca2+.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374361"}
{"pmid": "4374360", "title": "Hypertriglyceridaemia secondary to liver disease.", "content": "Hypertriglyceridaemia secondary to liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374360"}
{"pmid": "4374363", "title": "The contribution of adherent films of liquid on the cut surfaces of mouse brain slices to tissue water and \"extracellular\" marker space.", "content": "The contribution of adherent films of liquid on the cut surfaces of mouse brain slices to tissue water and \"extracellular\" marker space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374363"}
{"pmid": "4374364", "title": "An intracellular analysis of visual cortical neurones to moving stimuli: response in a co-operative neuronal network.", "content": "An intracellular analysis of visual cortical neurones to moving stimuli: response in a co-operative neuronal network.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374364"}
{"pmid": "4374357", "title": "Comparative toxicity on leukocytes and platelets of two regimens of CCNU: the relationship between maximum dose and optimum dose.", "content": "Comparative toxicity on leukocytes and platelets of two regimens of CCNU: the relationship between maximum dose and optimum dose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374357"}
{"pmid": "4374365", "title": "Post-tetanic effect on dorsal root reflex and flexor reflex in the forelimb of cats.", "content": "Post-tetanic effect on dorsal root reflex and flexor reflex in the forelimb of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374365"}
{"pmid": "4374366", "title": "Responses of interpositus neurones to inputs from muscle receptors.", "content": "Responses of interpositus neurones to inputs from muscle receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374366"}
{"pmid": "4374358", "title": "Biological properties of a C-type leuko-virus isolated from mouse myeloma cells.", "content": "Biological properties of a C-type leuko-virus isolated from mouse myeloma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374358"}
{"pmid": "4374367", "title": "Electrophysiological properties of lateral reticular nucleus cells: I. Antidromic activation.", "content": "Electrophysiological properties of lateral reticular nucleus cells: I. Antidromic activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374367"}
{"pmid": "4374369", "title": "Function Organization of primate oculomotor system revealed by cerebellectomy.", "content": "Function Organization of primate oculomotor system revealed by cerebellectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374369"}
{"pmid": "4374368", "title": "Electrophysiological properties of lateral reticular nucleus cells: II. Synaptic activation.", "content": "Electrophysiological properties of lateral reticular nucleus cells: II. Synaptic activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374368"}
{"pmid": "4374370", "title": "The lateral reticular nucleus in the cat. I. Mossy fibre distribution in cerebellar cortex.", "content": "The lateral reticular nucleus in the cat. I. Mossy fibre distribution in cerebellar cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374370"}
{"pmid": "4374371", "title": "The lateral reticular nucleus in the cat. II. Organization of component activated from bilateral ventral flexor reflex tract (bVFRT).", "content": "The lateral reticular nucleus in the cat. II. Organization of component activated from bilateral ventral flexor reflex tract (bVFRT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374371"}
{"pmid": "4374373", "title": "Ultrahistochemical demonstration of periodate reactive and alpha-amino groups in experimental amyloid.", "content": "Ultrahistochemical demonstration of periodate reactive and alpha-amino groups in experimental amyloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374373"}
{"pmid": "4374374", "title": "Paradoxical sleep and avoidance learning of Swiss white mice after early undernutrition by raising in large litters.", "content": "Paradoxical sleep and avoidance learning of Swiss white mice after early undernutrition by raising in large litters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374374"}
{"pmid": "4374375", "title": "The effect of reserpine and chlorimipramine on glycogen content in different brain structures of rat.", "content": "The effect of reserpine and chlorimipramine on glycogen content in different brain structures of rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374375"}
{"pmid": "4374376", "title": "Preliminary note on the occurrence of a biological compound showing fluorescence characteristics similar to that of NADH.", "content": "Preliminary note on the occurrence of a biological compound showing fluorescence characteristics similar to that of NADH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374376"}
{"pmid": "4374378", "title": "Mechanism of rearrangement of penicillin V (S)-sulfoxide into delta-2 and delta-3-cephem compounds.", "content": "Mechanism of rearrangement of penicillin V (S)-sulfoxide into delta-2 and delta-3-cephem compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374378"}
{"pmid": "4374377", "title": "A convenient colourimetric method for routine assay of brain adenylate cyclase.", "content": "A convenient colourimetric method for routine assay of brain adenylate cyclase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374377"}
{"pmid": "4374381", "title": "Determination of the oxidation-reduction potential of the bound iron-sulphur proteins of the primary electron acceptor complex of photosystem I in spinach chloroplasts.", "content": "Determination of the oxidation-reduction potential of the bound iron-sulphur proteins of the primary electron acceptor complex of photosystem I in spinach chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374381"}
{"pmid": "4374382", "title": "2,3-Diphosphoglycerate synthesis by human white ghosts.", "content": "2,3-Diphosphoglycerate synthesis by human white ghosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374382"}
{"pmid": "4374383", "title": "Sequence analysis of the 3'-T1 oligonucleotide of 16S ribosomal RNA from Escherichia coli.", "content": "Sequence analysis of the 3'-T1 oligonucleotide of 16S ribosomal RNA from Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374383"}
{"pmid": "4374384", "title": "Glutamine phosphoribosylpyrophosphate amidotransferase: increased activity in hepatomas.", "content": "Glutamine phosphoribosylpyrophosphate amidotransferase: increased activity in hepatomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374384"}
{"pmid": "4374386", "title": "Effects of hormones on cyclic AMP release from rat adipose tissue in vitro.", "content": "Effects of hormones on cyclic AMP release from rat adipose tissue in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374386"}
{"pmid": "4374385", "title": "Isolation of the regulatory subunit of pig-brain histone kinase by affinity chromatography on cyclic-AMP-containing adsorbent.", "content": "Isolation of the regulatory subunit of pig-brain histone kinase by affinity chromatography on cyclic-AMP-containing adsorbent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374385"}
{"pmid": "4374387", "title": "Inhibition of protein synthesis in tendon cells by extracts from experimental granulation tissue.", "content": "Inhibition of protein synthesis in tendon cells by extracts from experimental granulation tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374387"}
{"pmid": "4374388", "title": "Periplasmic CO-binding c-type cytochrome in a marine bacterium.", "content": "Periplasmic CO-binding c-type cytochrome in a marine bacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374388"}
{"pmid": "4374389", "title": "Consequences of the intracellular distribution of cyclic 3',5'-nucleotides phosphodiesterases.", "content": "Consequences of the intracellular distribution of cyclic 3',5'-nucleotides phosphodiesterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374389"}
{"pmid": "4374391", "title": "Neurophysin methylation in extracts of bovine posterior pituitary gland: hormone binding ability.", "content": "Neurophysin methylation in extracts of bovine posterior pituitary gland: hormone binding ability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374391"}
{"pmid": "4374390", "title": "Effect of ionophore A23187 on thyroid secretion.", "content": "Effect of ionophore A23187 on thyroid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374390"}
{"pmid": "4374392", "title": "Rapid, light-induced changes of retinal cyclic GMP levels.", "content": "Rapid, light-induced changes of retinal cyclic GMP levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374392"}
{"pmid": "4374393", "title": "Inhibition of mitochondrial malate dehydrogenase by 2-thenoyltrifluoroacetone.", "content": "Inhibition of mitochondrial malate dehydrogenase by 2-thenoyltrifluoroacetone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374393"}
{"pmid": "4374394", "title": "Phosphorylation of protein components of isolated zymogen granule membranes from the rat pancreas.", "content": "Phosphorylation of protein components of isolated zymogen granule membranes from the rat pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374394"}
{"pmid": "4374395", "title": "Two precursor 5S RNA species in Bacillus licheniformis: characterization and partial analysis of primary structure.", "content": "Two precursor 5S RNA species in Bacillus licheniformis: characterization and partial analysis of primary structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374395"}
{"pmid": "4374396", "title": "Presence of a cyclic-AMP-binding protein in Jerusalem artichoke rhizome tissues.", "content": "Presence of a cyclic-AMP-binding protein in Jerusalem artichoke rhizome tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374396"}
{"pmid": "4374397", "title": "Chloroplast and non-chloroplast adenosine-3':5'-cyclic-monophosphate-receptor-proteins in Euglena gracilis.", "content": "Chloroplast and non-chloroplast adenosine-3':5'-cyclic-monophosphate-receptor-proteins in Euglena gracilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374397"}
{"pmid": "4374398", "title": "Morphine antagonizes the action of prostaglandin in neuroblastoma cells but not of prostaglandin and noradrenaline in glioma and glioma times fibroblast hybrid cells.", "content": "Morphine antagonizes the action of prostaglandin in neuroblastoma cells but not of prostaglandin and noradrenaline in glioma and glioma times fibroblast hybrid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374398"}
{"pmid": "4374399", "title": "Interaction of Chinese hamster embryonic cells with the helper-dependent Rous sarcoma virus.", "content": "Interaction of Chinese hamster embryonic cells with the helper-dependent Rous sarcoma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374399"}
{"pmid": "4374400", "title": "Significance of acid amyloglucosidase in sulphonylurea-induced insulin release.", "content": "Significance of acid amyloglucosidase in sulphonylurea-induced insulin release.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374400"}
{"pmid": "4374404", "title": "Mechanism of actinomycin resistance in SV40-transformed hamster cells.", "content": "Mechanism of actinomycin resistance in SV40-transformed hamster cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374404"}
{"pmid": "4374403", "title": "Chemical and enzymatic changes in microsomes of chicken livers following stimulation by oestrogens.", "content": "Chemical and enzymatic changes in microsomes of chicken livers following stimulation by oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374403"}
{"pmid": "4374402", "title": "Hormone-induced maturation of Xenopus laevis oocytes: effects of different steroids and study of the properties of a progesterone receptor.", "content": "Hormone-induced maturation of Xenopus laevis oocytes: effects of different steroids and study of the properties of a progesterone receptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374402"}
{"pmid": "4374401", "title": "Effect of cholera toxin on insulin release in monolayer cultures of the endocrine pancreas.", "content": "Effect of cholera toxin on insulin release in monolayer cultures of the endocrine pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374401"}
{"pmid": "4374405", "title": "Cyclic AMP-elevating agents inhibit proliferation of keratinizing guinea pig epidermal cells.", "content": "Cyclic AMP-elevating agents inhibit proliferation of keratinizing guinea pig epidermal cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374405"}
{"pmid": "4374406", "title": "Abnormal regulation of cyclic AMP phosphodiesterase: a hypothesis for the development of cancer of nerve cells.", "content": "Abnormal regulation of cyclic AMP phosphodiesterase: a hypothesis for the development of cancer of nerve cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374406"}
{"pmid": "4374407", "title": "Intercellular interactions in eukaryotic homeostasis.", "content": "Intercellular interactions in eukaryotic homeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374407"}
{"pmid": "4374408", "title": "Mono- and triphosphate nucleotides, adenylatecyclase and phosphodiesterase activities in the intestine of normal or prolactin-treated Bufo bufo larvae.", "content": "Mono- and triphosphate nucleotides, adenylatecyclase and phosphodiesterase activities in the intestine of normal or prolactin-treated Bufo bufo larvae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374408"}
{"pmid": "4374409", "title": "Studies of metabolism in embryonic development. VI. Cortisol-binding proteins of trout embryos.", "content": "Studies of metabolism in embryonic development. VI. Cortisol-binding proteins of trout embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374409"}
{"pmid": "4374410", "title": "Misrepair mutagenesis in bacteriophage T4.", "content": "Misrepair mutagenesis in bacteriophage T4. The T4 mutations px, y and 1206 inactivate an error-prone recombination-like repair system, reducing or abolishing mutagenesis by UV irradiation, MMS, and white light irradiation in the presence of the photosensitizer 8MOP. Both px and y increase some spontaneous mutation rates and slightly enhance proflavin mutagenesis; neither mutation affects thymineless or 2AP mutagenesis appreciably, but both mildly enhance 5BU mutagenesis. The mutation hm promotes UV, MMS, photodynamic, thymineless, and base analog mutagenesis, in addition to spontaneous base pair substitution mutation. It does not, however, markedly affect proflavin mutagenesis. The px mutation maps in the vicinity of genes 41-56, and the hm mutation maps in the vicinity of genes rI-v.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374410"}
{"pmid": "4374411", "title": "Variation of mutagenic action on nonsense mutants at different sites in the iso-1-cytochrome c gene of yeast.", "content": "Variation of mutagenic action on nonsense mutants at different sites in the iso-1-cytochrome c gene of yeast. Three ochre and two amber mutants in yeast have been definitively identified by the amino acid replacements in iso-1-cytochromes c from intragenic revertants. Except for rare and sometimes unusual changes, all of the replacements were single amino acids whose codons differed from UAA or UAG by one base. These assignments, which were based on the absence of tryptophan replacements in ochre revertants, could be corroborated from the studies of two groups of suppressors that were shown to act on either the ochre or amber mutants. All five nonsense mutants are located at different sites in the cyc1 gene and all are at sites that can be occupied by amino acids having a wide range of structures. The relative frequencies of the amino acid replacements indicate that identical codons located at different sites may respond differently to a mutagenic agent. Notably glutamine replacements occurred almost exclusively in UV-induced revertants of only one ochre mutant cyc1-9, but not at all or at reduced proportions in the others. Similarly, lysine replacements occurred almost exclusively in the NA-induced revertants of only the ochre mutant cyc1-72, but not at all in the others. These and other results reveal that mutation of A.T base pairs by UV and nitrous acid are dependent upon the location of the codon within the gene as well as the location of the base pair within the codon. From these findings, it appears as if the type of base-pair changes induced by UV and nitrous acid are strongly influenced by adjacent nucleotide sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374411"}
{"pmid": "4374413", "title": "Histochemical study of traumatized muscle.", "content": "Histochemical study of traumatized muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374413"}
{"pmid": "4374415", "title": "Gelatinous adenocarcinoma of the renal pelvis.", "content": "Gelatinous adenocarcinoma of the renal pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374415"}
{"pmid": "4374416", "title": "Carcinogenicity of synthetic aflatoxin M1 in rats.", "content": "Carcinogenicity of synthetic aflatoxin M1 in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374416"}
{"pmid": "4374414", "title": "Histoenzymological observations of the response to injury and regeneration of the frog myocardium.", "content": "Histoenzymological observations of the response to injury and regeneration of the frog myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374414"}
{"pmid": "4374417", "title": "Educating for discharge planning.", "content": "Educating for discharge planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374417"}
{"pmid": "4374418", "title": "Hereditary malignant hyperpyrexia associated with muscle adenylate kinase deficiency.", "content": "Hereditary malignant hyperpyrexia associated with muscle adenylate kinase deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374418"}
{"pmid": "4374419", "title": "Osteo-onychodysostosis: a new family.", "content": "Osteo-onychodysostosis: a new family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374419"}
{"pmid": "4374420", "title": "Nephroblastoma in adult--a case report.", "content": "Nephroblastoma in adult--a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374420"}
{"pmid": "4374421", "title": "Uncommon polypoid tumours of nasal cavity.", "content": "Uncommon polypoid tumours of nasal cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374421"}
{"pmid": "4374422", "title": "Biological and biochemical studies on thioacetamide induced hepatocarcinogenesis.", "content": "Biological and biochemical studies on thioacetamide induced hepatocarcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374422"}
{"pmid": "4374423", "title": "Soft tissue tumours. I. Benign tumours.", "content": "Soft tissue tumours. I. Benign tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374423"}
{"pmid": "4374425", "title": "Malignant granular cell myoblastoma--report of a case.", "content": "Malignant granular cell myoblastoma--report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374425"}
{"pmid": "4374424", "title": "Soft tissue tumours. 2. Malignant tumours.", "content": "Soft tissue tumours. 2. Malignant tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374424"}
{"pmid": "4374426", "title": "Fatty acid composition of phospholipids and the phosphatidyl inositomannoside-antigens of mycobacteria.", "content": "Fatty acid composition of phospholipids and the phosphatidyl inositomannoside-antigens of mycobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374426"}
{"pmid": "4374427", "title": "Contribution on the clinical aspects and therapy of bronchial adenoma.", "content": "Contribution on the clinical aspects and therapy of bronchial adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374427"}
{"pmid": "4374429", "title": "Cytomegalovirus infection in Pondicherry (South India)--a serological survey.", "content": "Cytomegalovirus infection in Pondicherry (South India)--a serological survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374429"}
{"pmid": "4374428", "title": "Serial study of plasma angiotensin, electrolytes and juxta-glomerular index in experimental renal hypertension of monkeys.", "content": "Serial study of plasma angiotensin, electrolytes and juxta-glomerular index in experimental renal hypertension of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374428"}
{"pmid": "4374430", "title": "evaluation of egg inoculation and precipitation in gel test for laboratory diagnosis of smallpox.", "content": "evaluation of egg inoculation and precipitation in gel test for laboratory diagnosis of smallpox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374430"}
{"pmid": "4374431", "title": "Adreno-cortical function tests in lepra reaction.", "content": "Adreno-cortical function tests in lepra reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374431"}
{"pmid": "4374432", "title": "Agar gel-diffusion test with the sera of rabbits and monkeys inoculated with different strains of vaccinia virus.", "content": "Agar gel-diffusion test with the sera of rabbits and monkeys inoculated with different strains of vaccinia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374432"}
{"pmid": "4374433", "title": "Clostridium perfringens in hospital patients.", "content": "Clostridium perfringens in hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374433"}
{"pmid": "4374434", "title": "Primary bladder stone disease in children--crystallisation studies with special reference to urinary excretion of pyrophosphates.", "content": "Primary bladder stone disease in children--crystallisation studies with special reference to urinary excretion of pyrophosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374434"}
{"pmid": "4374435", "title": "Hyperlipoproteinemia type V (a case report).", "content": "Hyperlipoproteinemia type V (a case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374435"}
{"pmid": "4374437", "title": "113Sn/113Inm radioisotope generator systems.", "content": "113Sn/113Inm radioisotope generator systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374437"}
{"pmid": "4374438", "title": "A neuron model for simulation of frequency response characteristics.", "content": "A neuron model for simulation of frequency response characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374438"}
{"pmid": "4374439", "title": "Metronidazole ('Flagyl'): a pulse radiolysis and e.s.r. study.", "content": "Metronidazole ('Flagyl'): a pulse radiolysis and e.s.r. study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374439"}
{"pmid": "4374440", "title": "Multiplicity reactivation of human cytomegalovirus inactivated by ultra-violet light.", "content": "Multiplicity reactivation of human cytomegalovirus inactivated by ultra-violet light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374440"}
{"pmid": "4374441", "title": "Radicals in irradiated monocrystals of the base-pair complex 9-ethyl adenine: 1-methyl uracil.", "content": "Radicals in irradiated monocrystals of the base-pair complex 9-ethyl adenine: 1-methyl uracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374441"}
{"pmid": "4374443", "title": "Alcohol and nervous system with special reference to the enolic neuropathies.", "content": "Alcohol and nervous system with special reference to the enolic neuropathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374443"}
{"pmid": "4374442", "title": "Some biochemical effects of ethanol on CNS.", "content": "Some biochemical effects of ethanol on CNS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374442"}
{"pmid": "4374445", "title": "RNA polymerase activity and inhibition in herpesvirus-infected cells.", "content": "RNA polymerase activity and inhibition in herpesvirus-infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374445"}
{"pmid": "4374444", "title": "Community psychiatric nursing in Britain: an historical review.", "content": "Community psychiatric nursing in Britain: an historical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374444"}
{"pmid": "4374446", "title": "Enhanced replication of temperature-sensitive mutants of herpes simplex virus type 2 (HSV-2) at the nonpermissive temperature in cells transformed by HSV-2.", "content": "Enhanced replication of temperature-sensitive mutants of herpes simplex virus type 2 (HSV-2) at the nonpermissive temperature in cells transformed by HSV-2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374446"}
{"pmid": "4374448", "title": "On a new inhibition of poliovirus RNA replication.", "content": "On a new inhibition of poliovirus RNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374448"}
{"pmid": "4374447", "title": "A compendium of herpesviruses isolated from non-human primates.", "content": "A compendium of herpesviruses isolated from non-human primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374447"}
{"pmid": "4374450", "title": "Landre-Guillain-Barre syndrome associated with recent herpes virus hominis infection.", "content": "Landre-Guillain-Barre syndrome associated with recent herpes virus hominis infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374450"}
{"pmid": "4374451", "title": "Thyroid lymphography.", "content": "Thyroid lymphography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374451"}
{"pmid": "4374449", "title": "Prevalence of endogenous oncornavirus in guinea pigs.", "content": "Prevalence of endogenous oncornavirus in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374449"}
{"pmid": "4374455", "title": "Successive overlapping outbreaks of febrile pharyngitis and pharyngoconjunctival fever associated with adenovirus types 2 and 7, in a Kibbutz.", "content": "Successive overlapping outbreaks of febrile pharyngitis and pharyngoconjunctival fever associated with adenovirus types 2 and 7, in a Kibbutz.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374455"}
{"pmid": "4374456", "title": "Lipase activities in the lungs of rats subjected to experimental hypertriglyceridemia and fat embolism.", "content": "Lipase activities in the lungs of rats subjected to experimental hypertriglyceridemia and fat embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374456"}
{"pmid": "4374458", "title": "Feline leukemia virus and public health awareness.", "content": "Feline leukemia virus and public health awareness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374458"}
{"pmid": "4374461", "title": "Chloramphenicol--induced peripheral neuropathy (a case report).", "content": "Chloramphenicol--induced peripheral neuropathy (a case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374461"}
{"pmid": "4374460", "title": "Erythrocyte glucose-6-phosphate dehydrogenase deficiency in diabetes (maturity onset).", "content": "Erythrocyte glucose-6-phosphate dehydrogenase deficiency in diabetes (maturity onset).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374460"}
{"pmid": "4374462", "title": "Hepatic lymphography in cirrhosis of the liver.", "content": "Hepatic lymphography in cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374462"}
{"pmid": "4374459", "title": "The modulation of sensory input and motor output in autistic children.", "content": "The modulation of sensory input and motor output in autistic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374459"}
{"pmid": "4374465", "title": "Use of mannitol as an internal standard in the gas-liquid chromatography of methyl glycosides.", "content": "Use of mannitol as an internal standard in the gas-liquid chromatography of methyl glycosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374465"}
{"pmid": "4374466", "title": "Gas chromatographic analysis of the Alternaria metabolite, tenuazonic acid.", "content": "Gas chromatographic analysis of the Alternaria metabolite, tenuazonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374466"}
{"pmid": "4374469", "title": "Thin-layer chromatographic study of isoquinoline alkaloids with BN-CHAMBER.", "content": "Thin-layer chromatographic study of isoquinoline alkaloids with BN-CHAMBER.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374469"}
{"pmid": "4374453", "title": "Proceedings: Structural modifications of fructose 1,6-bisphosphatase and its regulation by histidine under gluconeogenic conditions.", "content": "Proceedings: Structural modifications of fructose 1,6-bisphosphatase and its regulation by histidine under gluconeogenic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374453"}
{"pmid": "4374464", "title": "Skeletal immaturity in psychiatrically disturbed adolescents.", "content": "Skeletal immaturity in psychiatrically disturbed adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374464"}
{"pmid": "4374470", "title": "Childhood acute lymphoblastic leukemia. a survey of children treated between 1963 and 1972 at Children's Memorial Hospital, Chicago.", "content": "Childhood acute lymphoblastic leukemia. a survey of children treated between 1963 and 1972 at Children's Memorial Hospital, Chicago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374470"}
{"pmid": "4374471", "title": "The nature of emergency room follow-up care.", "content": "The nature of emergency room follow-up care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374471"}
{"pmid": "4374472", "title": "Exaggerated response to levodopa. A case of \"contaminated parkinsonism\".", "content": "Exaggerated response to levodopa. A case of \"contaminated parkinsonism\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374472"}
{"pmid": "4374452", "title": "Characterization of NAD glycohydrolase from lymph duct lymphocytes.", "content": "Characterization of NAD glycohydrolase from lymph duct lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374452"}
{"pmid": "4374467", "title": "New solvent systems for the separation of free and conjugated bile acids.", "content": "New solvent systems for the separation of free and conjugated bile acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374467"}
{"pmid": "4374454", "title": "Proceedings: Metabolism of carbamyl phosphate in donkey liver.", "content": "Proceedings: Metabolism of carbamyl phosphate in donkey liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374454"}
{"pmid": "4374473", "title": "Significance of the Apgar score in the evaluation of mental retardation.", "content": "Significance of the Apgar score in the evaluation of mental retardation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374473"}
{"pmid": "4374474", "title": "Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy.", "content": "Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374474"}
{"pmid": "4374476", "title": "Modification of human neutrophil response to endotoxin with polymyxin B sulfate.", "content": "Modification of human neutrophil response to endotoxin with polymyxin B sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374476"}
{"pmid": "4374475", "title": "Comparison of the effects of enterotoxins of Shigella dysenteriae and Vibrio cholerae on the adenylate cyclase system of the rabbit intestine.", "content": "Comparison of the effects of enterotoxins of Shigella dysenteriae and Vibrio cholerae on the adenylate cyclase system of the rabbit intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374475"}
{"pmid": "4374477", "title": "Fecal Clostridium perfringens and rheumatoid arthritis.", "content": "Fecal Clostridium perfringens and rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374477"}
{"pmid": "4374479", "title": "Indication and technique for the reconstruction of nerve defects in head and neck.", "content": "Indication and technique for the reconstruction of nerve defects in head and neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374479"}
{"pmid": "4374480", "title": "Proceedings: Control of steroidogenesis in adrenal tissue from the developing opossum, Didelphis marsupialis virginiana.", "content": "Proceedings: Control of steroidogenesis in adrenal tissue from the developing opossum, Didelphis marsupialis virginiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374480"}
{"pmid": "4374481", "title": "Proceedings: Differences between the patterns of corticotrophin and luteinizing hormone release by perifused rat pituitaries in response to hypophysiotropic substances.", "content": "Proceedings: Differences between the patterns of corticotrophin and luteinizing hormone release by perifused rat pituitaries in response to hypophysiotropic substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374481"}
{"pmid": "4374482", "title": "Proceedings: In-vitro release of corticotrophin by the pars intermedia of the rainbow trout pituitary.", "content": "Proceedings: In-vitro release of corticotrophin by the pars intermedia of the rainbow trout pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374482"}
{"pmid": "4374483", "title": "The breast cancer discriminant: effect of age, obesity, hirsutism, starvation, and changes in adrenocortical and gonadal activity.", "content": "The breast cancer discriminant: effect of age, obesity, hirsutism, starvation, and changes in adrenocortical and gonadal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374483"}
{"pmid": "4374484", "title": "Nuclear and cytoplasmic oestrogen receptors in vaginal and uterine tissue of mice treated neonatally with steroids and prolactin.", "content": "Nuclear and cytoplasmic oestrogen receptors in vaginal and uterine tissue of mice treated neonatally with steroids and prolactin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374484"}
{"pmid": "4374485", "title": "Proceedings: The development of radioimmunoassays for 18-hydroxycorticosterone and 18-hydroxy-11-deoxycorticosterone.", "content": "Proceedings: The development of radioimmunoassays for 18-hydroxycorticosterone and 18-hydroxy-11-deoxycorticosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374485"}
{"pmid": "4374486", "title": "Diurnal changes in plasma testosterone and studies on plasma corticosteroids in non-anaesthetized male rhesus monkeys (Macaca mulatta).", "content": "Diurnal changes in plasma testosterone and studies on plasma corticosteroids in non-anaesthetized male rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374486"}
{"pmid": "4374487", "title": "Release of 131I from the ovary of the laying Japanese quail after injection of perchlorate, thiocyanate or iodide.", "content": "Release of 131I from the ovary of the laying Japanese quail after injection of perchlorate, thiocyanate or iodide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374487"}
{"pmid": "4374489", "title": "The non-electrogenic nature of angiotensin-stimulated sodium transport.", "content": "The non-electrogenic nature of angiotensin-stimulated sodium transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374489"}
{"pmid": "4374488", "title": "Plasma concentrations of cortisol in hypophysectomized and sodium chloride-adapted goldfish (Carassius auratus L.).", "content": "Plasma concentrations of cortisol in hypophysectomized and sodium chloride-adapted goldfish (Carassius auratus L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374488"}
{"pmid": "4374491", "title": "Proceedings: Evidence for a specific oestradiol-binding protein in neonatal rat brain.", "content": "Proceedings: Evidence for a specific oestradiol-binding protein in neonatal rat brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374491"}
{"pmid": "4374490", "title": "Proceedings: Familial glucocorticoid deficiency.", "content": "Proceedings: Familial glucocorticoid deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374490"}
{"pmid": "4374493", "title": "Proceedings: Human placental oestradiol-17beta dehydrogenase affinity labelled at the active region.", "content": "Proceedings: Human placental oestradiol-17beta dehydrogenase affinity labelled at the active region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374493"}
{"pmid": "4374492", "title": "Proceedings: The relationship between oestradiol-17beta receptor concentration and endogenous oestradiol-17beta in human breast tumour tissue.", "content": "Proceedings: The relationship between oestradiol-17beta receptor concentration and endogenous oestradiol-17beta in human breast tumour tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374492"}
{"pmid": "4374494", "title": "Proceedings: Factors influencing the stimulation of prostatic RNA polymerase by 5alpha-dihydrotestosterone-receptor complexes.", "content": "Proceedings: Factors influencing the stimulation of prostatic RNA polymerase by 5alpha-dihydrotestosterone-receptor complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374494"}
{"pmid": "4374495", "title": "Proceedings: The thyroid-stimulating hormone receptor and thyroid-stimulating antibodies.", "content": "Proceedings: The thyroid-stimulating hormone receptor and thyroid-stimulating antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374495"}
{"pmid": "4374496", "title": "Pharmacological studies on a locust neuromuscular preparation.", "content": "Pharmacological studies on a locust neuromuscular preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374496"}
{"pmid": "4374497", "title": "The possible involvement of brain microtubules in memory fixation.", "content": "The possible involvement of brain microtubules in memory fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374497"}
{"pmid": "4374498", "title": "Pharmacological induction of plasticization in the abdominal cuticle of Rhodnius.", "content": "Pharmacological induction of plasticization in the abdominal cuticle of Rhodnius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374498"}
{"pmid": "4374499", "title": "Estimation of age from skeletal remains.", "content": "Estimation of age from skeletal remains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374499"}
{"pmid": "4374500", "title": "Equilibrium potential for the postsynaptic response in the squid giant synapse.", "content": "Equilibrium potential for the postsynaptic response in the squid giant synapse. The reversal potential for the EPSP in the squid giant synapse has been studied by means of an intracellular, double oil gap technique. This method allows the electrical isolation of a portion of the axon from the rest of the fiber and generates a quasi-isopotential segment. In order to make the input resistance of this nerve segment as constant as possible, the electroresponsive properties of the nerve membrane were blocked by intracellular injection of tetraethylammonium (TEA) and local extracellular application of tetrodotoxin (TTX). Thus, EPSP's could be evoked in the isolated segment with a minimal amount of electroresponsive properties. The reversal potential for the EPSP (EEPSP) was measured by recording the synaptic potential or the synaptic current during voltage clamping. The results indicate that EEPSP may vary from +15 to +25 mV, which is more positive than would be expected for a 1:1 conductance change for Na(+) and K(+) (approximately -15 mV) and too negative for a pure Na(+) conductance ((+)40 mV). This latter value (E(Na)) was directly determined in the voltage clamp experiments. The results suggest that the synaptic potential is probably produced by a permeability change to Na(+) to K(+) in a 4:1 ratio. No change in time-course was observed in the synaptic current at clamp levels of -100 and +90 mV. The implications of a variable ratio for Na(+)-K(+) permeability in subsynaptic-postsynaptic membranes are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374500"}
{"pmid": "4374501", "title": "Adenovirus antigens: a model system in mice for subunit vaccination.", "content": "Adenovirus antigens: a model system in mice for subunit vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374501"}
{"pmid": "4374502", "title": "Mechanism of interferon induction by NDV: A MONOLAYER AND SINGLE CELL STUDY.", "content": "Mechanism of interferon induction by NDV: A MONOLAYER AND SINGLE CELL STUDY.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374502"}
{"pmid": "4374504", "title": "Isolation and preliminary characterization of temperature-sensitive mutants of Sindbis virus strain AR339.", "content": "Isolation and preliminary characterization of temperature-sensitive mutants of Sindbis virus strain AR339.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374504"}
{"pmid": "4374503", "title": "Lysosomal enzyme activity in poliovirus-infected HeLa cells and vesicular stomatitis virus-infected L cells: biochemical and histochemical comparative analysis with computer-aided techniques.", "content": "Lysosomal enzyme activity in poliovirus-infected HeLa cells and vesicular stomatitis virus-infected L cells: biochemical and histochemical comparative analysis with computer-aided techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374503"}
{"pmid": "4374505", "title": "Artificial assembly of envelope particles of HVJ (Sendai virus). Fusion activity of envelope particles.", "content": "Artificial assembly of envelope particles of HVJ (Sendai virus). Fusion activity of envelope particles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374505"}
{"pmid": "4374506", "title": "Herpes simplex virus-induced enhancement of mitochondrial DNA synthesis in the absence of virus replication.", "content": "Herpes simplex virus-induced enhancement of mitochondrial DNA synthesis in the absence of virus replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374506"}
{"pmid": "4374508", "title": "Anterior interosseous nerve palsy: spontaneous recovery in two patients.", "content": "Anterior interosseous nerve palsy: spontaneous recovery in two patients. The case histories of two patients who developed an anterior interosseous nerve palsy apparently as a result of an external pressure injury are reported. Both patients recovered fully without surgical exploration, one 19 months and the other nine months after the onset. It is stressed that complete recovery may occur spontaneously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374508"}
{"pmid": "4374507", "title": "The cerebellum in mucopolysaccharidosis. A histological, histochemical, and ultrastructural study.", "content": "The cerebellum in mucopolysaccharidosis. A histological, histochemical, and ultrastructural study. Studies in the morphology, histochemistry, and ultrastructure of the cerebellum, with special reference to the Purkinje cell dendrites, have been undertaken in eight cases of gargoylism. The results suggest that the demonstration of ovoid swellings of the Purkinje cell dendrites by the Cajal method for the cerebellum, together with certain histochemical findings, may enable a diagnosis of mucopolysaccharidosis to be made. Possible mechanisms for the formation of these swellings are briefly discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374507"}
{"pmid": "4374510", "title": "Toxic polyneuropathy due to glue-sniffing. Report of two cases with a light and electron-microscopic study of the peripheral nerves and muscles.", "content": "Toxic polyneuropathy due to glue-sniffing. Report of two cases with a light and electron-microscopic study of the peripheral nerves and muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374510"}
{"pmid": "4374509", "title": "Encephalitis associated with carcinoma. Central hypoventilation syndrome and cytoplasmic inclusion bodies.", "content": "Encephalitis associated with carcinoma. Central hypoventilation syndrome and cytoplasmic inclusion bodies. A case of encephalitis associated with a remote and occult oat cell carcinoma is presented in which the main clinical features were progressive dementia and central hypoventilation syndrome. The only significant anatomical lesions within the known anatomical substrate of respiration affected the locus caeruleus on both sides. It is speculated that the degeneration of the locus caeruleus was responsible for the central hypoventilation syndrome. Hitherto undescribed neuronal intracytoplasmic eosinophilic inclusions were found in an isolated lesion of the insular cortex. Electron microscopy failed to disclose viral particles in the regions of neuronal degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374509"}
{"pmid": "4374511", "title": "GM1 gangliosidosis.", "content": "GM1 gangliosidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374511"}
{"pmid": "4374512", "title": "Ultrastructural changes of muscle in malignant hyperthermia.", "content": "Ultrastructural changes of muscle in malignant hyperthermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374512"}
{"pmid": "4374513", "title": "Oculopharyngeal muscular dystrophy. A case with abnormal mitochondria and \"fingerprint\" inclusions.", "content": "Oculopharyngeal muscular dystrophy. A case with abnormal mitochondria and \"fingerprint\" inclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374513"}
{"pmid": "4374514", "title": "Ultrastructural demonstration of neuronal storage in fetal Tay-Sachs disease.", "content": "Ultrastructural demonstration of neuronal storage in fetal Tay-Sachs disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374514"}
{"pmid": "4374516", "title": "Neutralizing antibodies to poliovirus and mumps virus in amyotrophic lateral sclerosis.", "content": "Neutralizing antibodies to poliovirus and mumps virus in amyotrophic lateral sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374516"}
{"pmid": "4374517", "title": "Leiomyosarcoma of the breast originating from myothelium (myoepithelium).", "content": "Leiomyosarcoma of the breast originating from myothelium (myoepithelium).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374517"}
{"pmid": "4374515", "title": "Biochemical and ultrastructural studies on subacute sclerosing panencephalitis and demyelination.", "content": "Biochemical and ultrastructural studies on subacute sclerosing panencephalitis and demyelination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374515"}
{"pmid": "4374518", "title": "Greater frequency of viral respiratory infections in asthmatic children as compared with their nonasthmatic siblings.", "content": "Greater frequency of viral respiratory infections in asthmatic children as compared with their nonasthmatic siblings. A longitudinal clincal and microbiologic surveillance was conducted from October to May, 1971-72, on 16 children with infectious asthma and 15 of their nonasthmatic siblings. Asthmatic children experienced a significantly greater frequency of viral respiratory infections than did nonasthmatic ones (5.1 vs. 3.8 per subject). This increased incidence appeared to be largely the result of a greater number of rhinovirus infections. While respiratory infections of identical etiology that occurred concurrently in an asthmatic and his sibling were equivalent in severity, illnesses were longer (but not significantly so) in asthmatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374518"}
{"pmid": "4374519", "title": "Cerebrospinal fluid: presence of virus unaccompanied by pleocytosis.", "content": "Cerebrospinal fluid: presence of virus unaccompanied by pleocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374519"}
{"pmid": "4374520", "title": "Pertussis: persistent problems.", "content": "Pertussis: persistent problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374520"}
{"pmid": "4374521", "title": "Proceedings: Increase in the cyclic AMP content of rat striatum produced by a cyclic analogue of dopamine.", "content": "Proceedings: Increase in the cyclic AMP content of rat striatum produced by a cyclic analogue of dopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374521"}
{"pmid": "4374523", "title": "Proceedings: Halothane and the depression of synaptic transmission through the perforant path synapses of the dentate gyrus of the hippocampal formation.", "content": "Proceedings: Halothane and the depression of synaptic transmission through the perforant path synapses of the dentate gyrus of the hippocampal formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374523"}
{"pmid": "4374522", "title": "Calcium release in relation to permeability changes in toad bladder epithelium following antidiuretic hormone.", "content": "Calcium release in relation to permeability changes in toad bladder epithelium following antidiuretic hormone. 1. Methods for measuring the release of (45)Ca from isolated urinary bladders of toads (Bufo marinus) pre-loaded with this isotope have been devised. One method allowed separate collection from the mucosal and serosal surfaces of the bladders.2. Reducing the ambient calcium concentration reduced the rate of (45)Ca efflux suggesting that efflux of radiolabel represents calcium exchange.3. Antidiuretic hormone, theophylline and prostaglandin E(1) all increased calcium efflux, while lanthanum and amphotericin were without effect. Cyclic AMP caused only an inhibition of calcium release.4. The increase in (45)Ca efflux due to antidiuretic hormone came exclusively from the mucosal side. Experiments with EGTA suggest that the calcium entering the mucosal solution arises mainly from superficial sites in the mucosal membrane.5. The release of (45)Ca by hormone was not influenced by removal of sodium from the bathing solution. Low pH and amiloride reduced or abolished calcium release to hormone.6. The time course of calcium release from the mucosal surface due to hormone was rapid (commencing between 0.5 and 1.5 min after hormone application). Thus calcium release precedes the increase in sodium transport and hydro-osmotic flow following hormone, and appears to be at least as rapid as cyclic AMP generation in the tissue.7. The relationship between calcium release or exchange and the permeability changes in the bladder to water and to sodium, following hormone, are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374522"}
{"pmid": "4374526", "title": "East meets west: a transcultural aspect of the nurse-patient relationship.", "content": "East meets west: a transcultural aspect of the nurse-patient relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374526"}
{"pmid": "4374525", "title": "The pediatric nurse practitioner and preventive community mental health.", "content": "The pediatric nurse practitioner and preventive community mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374525"}
{"pmid": "4374528", "title": "Issues between professional and paraprofessional nursing staff in community mental health.", "content": "Issues between professional and paraprofessional nursing staff in community mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374528"}
{"pmid": "4374524", "title": "The Cinderella syndrome--young women in crisis.", "content": "The Cinderella syndrome--young women in crisis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374524"}
{"pmid": "4374530", "title": "Preventive intervention: healing in West Africa.", "content": "Preventive intervention: healing in West Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374530"}
{"pmid": "4374540", "title": "The orgins of stromal reaction in breast carcinoma.", "content": "The orgins of stromal reaction in breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374540"}
{"pmid": "4374541", "title": "Arteriovenous aneurysm due to glomangioma.", "content": "Arteriovenous aneurysm due to glomangioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374541"}
{"pmid": "4374532", "title": "Rehabilitating heroin addicts.", "content": "Rehabilitating heroin addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374532"}
{"pmid": "4374527", "title": "Transactional analysis strategies for dealing with pain.", "content": "Transactional analysis strategies for dealing with pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374527"}
{"pmid": "4374534", "title": "Methadone maintenance.", "content": "Methadone maintenance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374534"}
{"pmid": "4374531", "title": "Family nurse therapist: a model of communication.", "content": "Family nurse therapist: a model of communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374531"}
{"pmid": "4374529", "title": "Psychiatric drugs and trends.", "content": "Psychiatric drugs and trends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374529"}
{"pmid": "4374543", "title": "Attempts to detect cytomegalovirus and rubella virus in infants with indirect inguinal hernias.", "content": "Attempts to detect cytomegalovirus and rubella virus in infants with indirect inguinal hernias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374543"}
{"pmid": "4374542", "title": "Modification of the lymphocyte response to mitogens by cyclic AMP and GMP.", "content": "Modification of the lymphocyte response to mitogens by cyclic AMP and GMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374542"}
{"pmid": "4374535", "title": "Patterning for a constructive relationship in problem isolation.", "content": "Patterning for a constructive relationship in problem isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374535"}
{"pmid": "4374538", "title": "Geriatrics: historical background & social security analysis.", "content": "Geriatrics: historical background & social security analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374538"}
{"pmid": "4374545", "title": "An energy filter for biological electron microscopy.", "content": "An energy filter for biological electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374545"}
{"pmid": "4374544", "title": "Cell communication: a cyclic AMP mediated phenomenon.", "content": "Cell communication: a cyclic AMP mediated phenomenon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374544"}
{"pmid": "4374546", "title": "Direct determination of DNA nucleotide sequences: structure of a fragment of bacteriophage phiX172 DNA.", "content": "Direct determination of DNA nucleotide sequences: structure of a fragment of bacteriophage phiX172 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374546"}
{"pmid": "4374533", "title": "Los Angeles teen challenge: a resocialization program for drug abusers.", "content": "Los Angeles teen challenge: a resocialization program for drug abusers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374533"}
{"pmid": "4374547", "title": "Letter to the editor: Fusion of Sendai viruses with model membranes.", "content": "Letter to the editor: Fusion of Sendai viruses with model membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374547"}
{"pmid": "4374548", "title": "Hemophilus aegyptius restriction edonuclease cleavage map of the simian virus 40 genome and its colinear relation with the hemophilus influenzae cleavage map of SV40.", "content": "Hemophilus aegyptius restriction edonuclease cleavage map of the simian virus 40 genome and its colinear relation with the hemophilus influenzae cleavage map of SV40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374548"}
{"pmid": "4374536", "title": "Caring for patients with alcohol problems.", "content": "Caring for patients with alcohol problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374536"}
{"pmid": "4374549", "title": "The methylated nucleotide sequences in HELA cell ribosomal RNA and its precursors.", "content": "The methylated nucleotide sequences in HELA cell ribosomal RNA and its precursors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374549"}
{"pmid": "4374537", "title": "International Trends: nursing in a changing world.", "content": "International Trends: nursing in a changing world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374537"}
{"pmid": "4374550", "title": "A comparison of the denatured states of alpha-lactalbumin and lysozyme.", "content": "A comparison of the denatured states of alpha-lactalbumin and lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374550"}
{"pmid": "4374539", "title": "The clinical specialist as a change agent.", "content": "The clinical specialist as a change agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374539"}
{"pmid": "4374551", "title": "Structure of two adenovirus-simian virus 40 hybrids which contain the entire SV40 genome.", "content": "Structure of two adenovirus-simian virus 40 hybrids which contain the entire SV40 genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374551"}
{"pmid": "4374552", "title": "Deletion mutants of simian virus 40 generated by enzymatic excision of DNA segments from the viral genome.", "content": "Deletion mutants of simian virus 40 generated by enzymatic excision of DNA segments from the viral genome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374552"}
{"pmid": "4374553", "title": "Structural and functional similarities within the coenzyme binding domains of dehydrogenases.", "content": "Structural and functional similarities within the coenzyme binding domains of dehydrogenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374553"}
{"pmid": "4374554", "title": "Relaxation spectra of the iron spin transition in methemoglobin.", "content": "Relaxation spectra of the iron spin transition in methemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374554"}
{"pmid": "4374555", "title": "Selective experimental chelation of calcium in the sinus node.", "content": "Selective experimental chelation of calcium in the sinus node.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374555"}
{"pmid": "4374556", "title": "Serological evidence of arbovirus infection in febrile hospitalized patients in Jakarta, Indonesia during 1970-71.", "content": "Serological evidence of arbovirus infection in febrile hospitalized patients in Jakarta, Indonesia during 1970-71.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374556"}
{"pmid": "4374565", "title": "Factors influencing the establishment of persistent infection of HVJ (Sendai virus)in L cells.", "content": "Factors influencing the establishment of persistent infection of HVJ (Sendai virus)in L cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374565"}
{"pmid": "4374566", "title": "Studies on complement-fixation reaction in equine infectious anemia. I. Development and activities of complement-fixing and complement fixation-inhibiting antibodies.", "content": "Studies on complement-fixation reaction in equine infectious anemia. I. Development and activities of complement-fixing and complement fixation-inhibiting antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374566"}
{"pmid": "4374567", "title": "Studies on the neutralization of herpes simplex virus. VII. Reevaluation of the equilibrium theory concerning the unneutralizable persistent fraction.", "content": "Studies on the neutralization of herpes simplex virus. VII. Reevaluation of the equilibrium theory concerning the unneutralizable persistent fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374567"}
{"pmid": "4374570", "title": "Studies on the mechanism and prevention of local recurrence of carcinoma at the suture line after colonic resection.", "content": "Studies on the mechanism and prevention of local recurrence of carcinoma at the suture line after colonic resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374570"}
{"pmid": "4374571", "title": "A pathologic-anatomical feature of carcinoma of large bowel in Japan.", "content": "A pathologic-anatomical feature of carcinoma of large bowel in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374571"}
{"pmid": "4374590", "title": "Cryptosporidiosis in the intestines of rhesus monkeys (Macaca mulatta).", "content": "Cryptosporidiosis in the intestines of rhesus monkeys (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374590"}
{"pmid": "4374591", "title": "Effectiveness of footwear decontamination methods for preventing the spread of infectious agents.", "content": "Effectiveness of footwear decontamination methods for preventing the spread of infectious agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374591"}
{"pmid": "4374593", "title": "Iron balance in the mouse.", "content": "Iron balance in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374593"}
{"pmid": "4374592", "title": "Fetal and postnatal growth retardation associated with gestational mumps virus infection of the rhesus monkey.", "content": "Fetal and postnatal growth retardation associated with gestational mumps virus infection of the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374592"}
{"pmid": "4374594", "title": "An evaluation of requirements for pathological incineration facilities.", "content": "An evaluation of requirements for pathological incineration facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374594"}
{"pmid": "4374595", "title": "Population frequency of erythrocyte antigens in the rhesus monkey.", "content": "Population frequency of erythrocyte antigens in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374595"}
{"pmid": "4374596", "title": "Cysticercosis in rabbits: incidence and lesions of the naturally occurring disease in young domestic rabbits.", "content": "Cysticercosis in rabbits: incidence and lesions of the naturally occurring disease in young domestic rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374596"}
{"pmid": "4374597", "title": "Evaluating feeding cycles of small rodents.", "content": "Evaluating feeding cycles of small rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374597"}
{"pmid": "4374598", "title": "Pasteurella multocida infection in the opossum (Didelphis virginiana).", "content": "Pasteurella multocida infection in the opossum (Didelphis virginiana).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374598"}
{"pmid": "4374599", "title": "An isolator for the collection of feces from chickens infected with coccidia.", "content": "An isolator for the collection of feces from chickens infected with coccidia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374599"}
{"pmid": "4374600", "title": "The time and pattern of eruption of the permanent teeth of the cat.", "content": "The time and pattern of eruption of the permanent teeth of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374600"}
{"pmid": "4374601", "title": "An improved method for fibrin clot recovery.", "content": "An improved method for fibrin clot recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374601"}
{"pmid": "4374602", "title": "Mechanical milk collection from mice for Bittner virus isolation.", "content": "Mechanical milk collection from mice for Bittner virus isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374602"}
{"pmid": "4374603", "title": "Naturally occurring Sendai virus disease of mice.", "content": "Naturally occurring Sendai virus disease of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374603"}
{"pmid": "4374604", "title": "An ultrahigh-efficiency filter for use with flexible film germfree animal isolators.", "content": "An ultrahigh-efficiency filter for use with flexible film germfree animal isolators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374604"}
{"pmid": "4374605", "title": "Exteriorized ureters in the dog.", "content": "Exteriorized ureters in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374605"}
{"pmid": "4374606", "title": "A simple method for repeated plasmapheresis of the horse.", "content": "A simple method for repeated plasmapheresis of the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374606"}
{"pmid": "4374607", "title": "Effects of off-frequency detection in brief-tone audiometry.", "content": "Effects of off-frequency detection in brief-tone audiometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374607"}
{"pmid": "4374610", "title": "Hepatic artery-portal vein fistula with hepatic cirrhosis, hepatoma and bleeding esophageal varices.", "content": "Hepatic artery-portal vein fistula with hepatic cirrhosis, hepatoma and bleeding esophageal varices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374610"}
{"pmid": "4374611", "title": "Primary linitis plastica carcinoma of the colon.", "content": "Primary linitis plastica carcinoma of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374611"}
{"pmid": "4374613", "title": "Learning, brain noradrenaline and the pituitary--adrenal axis.", "content": "Learning, brain noradrenaline and the pituitary--adrenal axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374613"}
{"pmid": "4374612", "title": "Selective metabolic pathways for noradrena-line in the peripheral and in the central nervous system.", "content": "Selective metabolic pathways for noradrena-line in the peripheral and in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374612"}
{"pmid": "4374608", "title": "Detection and differentiation of primary hyperlipoproteinemias.", "content": "Detection and differentiation of primary hyperlipoproteinemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374608"}
{"pmid": "4374614", "title": "Effect of 6-hydroxydopamine on agonistic behaviour elicited by stimulation of the hypothalamus in the cat.", "content": "Effect of 6-hydroxydopamine on agonistic behaviour elicited by stimulation of the hypothalamus in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374614"}
{"pmid": "4374616", "title": "Sensitized guinea-pig lung: altered adenylate cyclase stimulation by epinephrine.", "content": "Sensitized guinea-pig lung: altered adenylate cyclase stimulation by epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374616"}
{"pmid": "4374609", "title": "Fine structural changes in the lateral vestibular nucleus of aging rats.", "content": "Fine structural changes in the lateral vestibular nucleus of aging rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374609"}
{"pmid": "4374623", "title": "Skin cancer.", "content": "Skin cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374623"}
{"pmid": "4374622", "title": "Lipids of cultured hepatoma cells: V. Distribution of isomeric monoene fatty acids in individual lipid classes.", "content": "Lipids of cultured hepatoma cells: V. Distribution of isomeric monoene fatty acids in individual lipid classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374622"}
{"pmid": "4374621", "title": "Lipids of cultured hepatoma cells: IV. Effect of serum and lipid upon cellular and media neutral lipids.", "content": "Lipids of cultured hepatoma cells: IV. Effect of serum and lipid upon cellular and media neutral lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374621"}
{"pmid": "4374626", "title": "Mammalian membrane marker enzymes: sensitive assay for 5'-nucleotidase and assay for mammalian 2',3'-cyclic-nucleotide-3'-phosphohydrolase.", "content": "Mammalian membrane marker enzymes: sensitive assay for 5'-nucleotidase and assay for mammalian 2',3'-cyclic-nucleotide-3'-phosphohydrolase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374626"}
{"pmid": "4374628", "title": "Isolation and characterization of glycosphingolipid from animal cells and their membranes.", "content": "Isolation and characterization of glycosphingolipid from animal cells and their membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374628"}
{"pmid": "4374627", "title": "Spin-label measurements in membranes. With appendix: a use of computers in EPR spectroscopy.", "content": "Spin-label measurements in membranes. With appendix: a use of computers in EPR spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374627"}
{"pmid": "4374629", "title": "C55-isoprenoid alcohol phosphokinase: an enzyme soluble in organic solvents.", "content": "C55-isoprenoid alcohol phosphokinase: an enzyme soluble in organic solvents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374629"}
{"pmid": "4374630", "title": "Cell hybridization.", "content": "Cell hybridization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374630"}
{"pmid": "4374631", "title": "Coulter electronic particle counter assay.", "content": "Coulter electronic particle counter assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374631"}
{"pmid": "4374632", "title": "Assays for agglutination with lectins,.", "content": "Assays for agglutination with lectins,.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374632"}
{"pmid": "4374633", "title": "An assay for labeled lectin binding to cell surfaces.", "content": "An assay for labeled lectin binding to cell surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374633"}
{"pmid": "4374634", "title": "High-yield preparation of morphologically intact isolated parenchymal cells from rat liver.", "content": "High-yield preparation of morphologically intact isolated parenchymal cells from rat liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374634"}
{"pmid": "4374635", "title": "Isolation of adult rat liver macrophages (Kupffer cells).", "content": "Isolation of adult rat liver macrophages (Kupffer cells).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374635"}
{"pmid": "4374636", "title": "Isolation of renal tubules.", "content": "Isolation of renal tubules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374636"}
{"pmid": "4374638", "title": "Isolation of adrenal cortex cells--hormone responses.", "content": "Isolation of adrenal cortex cells--hormone responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374638"}
{"pmid": "4374639", "title": "The isolation and culture of thyroid cells.", "content": "The isolation and culture of thyroid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374639"}
{"pmid": "4374637", "title": "Isolation of intestinal mucosa cells.", "content": "Isolation of intestinal mucosa cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374637"}
{"pmid": "4374640", "title": "Yeast lipid mutants: isolation, maintenance, and spin label studies.", "content": "Yeast lipid mutants: isolation, maintenance, and spin label studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374640"}
{"pmid": "4374647", "title": "Ribonucleic acid synthesis in rinderpest virus infected cells.", "content": "Ribonucleic acid synthesis in rinderpest virus infected cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374647"}
{"pmid": "4374646", "title": "Measles, canine distemper and respiratory syncytial virions and nucleocapsids. A comparative study of their structure, polypeptide and nucleic acid composition.", "content": "Measles, canine distemper and respiratory syncytial virions and nucleocapsids. A comparative study of their structure, polypeptide and nucleic acid composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374646"}
{"pmid": "4374648", "title": "Pathogenetic aspects of measles virus infections.", "content": "Pathogenetic aspects of measles virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374648"}
{"pmid": "4374649", "title": "Parainfluenza 1 virus and multiple sclerosis: the conversion of 6/94 virus released from human brain cells and other mammalian cells into and infectious form by passage in macrophages.", "content": "Parainfluenza 1 virus and multiple sclerosis: the conversion of 6/94 virus released from human brain cells and other mammalian cells into and infectious form by passage in macrophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374649"}
{"pmid": "4374652", "title": "Isolation, genetics and survival characteristics of thermo-sensitive mutants of yeast.", "content": "Isolation, genetics and survival characteristics of thermo-sensitive mutants of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374652"}
{"pmid": "4374661", "title": "Electrophoretic protein and enzyme patterns and antigenic structure in Verticillium dahliae and V. albo-atrum.", "content": "Electrophoretic protein and enzyme patterns and antigenic structure in Verticillium dahliae and V. albo-atrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374661"}
{"pmid": "4374662", "title": "Isolation of bovine rhinovirus from calves with respiratory disease.", "content": "Isolation of bovine rhinovirus from calves with respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374662"}
{"pmid": "4374663", "title": "Isolation of bacteria and viruses from aborted bovine fetuses.", "content": "Isolation of bacteria and viruses from aborted bovine fetuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374663"}
{"pmid": "4374667", "title": "Ocular flutter and downbeat nystagmus: a case with supratentorial origin?", "content": "Ocular flutter and downbeat nystagmus: a case with supratentorial origin?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374667"}
{"pmid": "4374668", "title": "Neural neoplasms in Thailand: a study of 2,897 cases.", "content": "Neural neoplasms in Thailand: a study of 2,897 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374668"}
{"pmid": "4374669", "title": "Gastrointestinal involvement in von Recklinghausen's neurofibromatosis.", "content": "Gastrointestinal involvement in von Recklinghausen's neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374669"}
{"pmid": "4374672", "title": "Infectious bovine rhinotracheitis virus and its role in bovine abortion.", "content": "Infectious bovine rhinotracheitis virus and its role in bovine abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374672"}
{"pmid": "4374674", "title": "Osteochondromatosis of the temporomandibular joint. Report of a case.", "content": "Osteochondromatosis of the temporomandibular joint. Report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374674"}
{"pmid": "4374673", "title": "The epidemiology of Type 2 (genital) herpes simplex virus infection.", "content": "The epidemiology of Type 2 (genital) herpes simplex virus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374673"}
{"pmid": "4374675", "title": "The dentinal changes in regional odontodysplasia.", "content": "The dentinal changes in regional odontodysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374675"}
{"pmid": "4374676", "title": "Effects of phenylbutazone on the activities of cathepsin D, collagenolytic cathepsin and collagen peptidase in turpentine-induced granuloma.", "content": "Effects of phenylbutazone on the activities of cathepsin D, collagenolytic cathepsin and collagen peptidase in turpentine-induced granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374676"}
{"pmid": "4374681", "title": "The long term effects of infection in early life (long view II). Presidential Address delivered at the Symposium on the Long Term Effects of Events in Early Life, American Pediatric Society annual meeting, May 1, 1974, Washington, D.C.", "content": "The long term effects of infection in early life (long view II). Presidential Address delivered at the Symposium on the Long Term Effects of Events in Early Life, American Pediatric Society annual meeting, May 1, 1974, Washington, D.C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374681"}
{"pmid": "4374680", "title": "Studies on the pathogenetic mechanism of I-cell disease in cultured fibroblasts.", "content": "Studies on the pathogenetic mechanism of I-cell disease in cultured fibroblasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374680"}
{"pmid": "4374688", "title": "Nursing care study: fructose-1, 6-diphosphatase deficiency-1.", "content": "Nursing care study: fructose-1, 6-diphosphatase deficiency-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374688"}
{"pmid": "4374689", "title": "Fructose-1, 6 diphosphatase deficiency. 2.", "content": "Fructose-1, 6 diphosphatase deficiency. 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374689"}
{"pmid": "4374694", "title": "Bronchial asthma.", "content": "Bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374694"}
{"pmid": "4374696", "title": "Rapid method for the isolation of plasma membranes from a murine fibrosarcoma using an aqueous two-phase polymer system.", "content": "Rapid method for the isolation of plasma membranes from a murine fibrosarcoma using an aqueous two-phase polymer system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374696"}
{"pmid": "4374700", "title": "Dual infection with endogenous herpes- and C-type viruses in cultured cells derived from normal and leukemic guinea pigs.", "content": "Dual infection with endogenous herpes- and C-type viruses in cultured cells derived from normal and leukemic guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374700"}
{"pmid": "4374701", "title": "Cyclic AMP and thyroid hormone: inhibition of epiphyseal cartilage cyclic 3',5'-nucleotide phosphodiesterase activity by L-triiodothyronine.", "content": "Cyclic AMP and thyroid hormone: inhibition of epiphyseal cartilage cyclic 3',5'-nucleotide phosphodiesterase activity by L-triiodothyronine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374701"}
{"pmid": "4374702", "title": "Tumor facilitation in a syngeneic host-tumor system.", "content": "Tumor facilitation in a syngeneic host-tumor system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374702"}
{"pmid": "4374692", "title": "Influence of ouabain on active sodium transport, stimulated by cyclic nucleotides across the frog skin in vivo.", "content": "Influence of ouabain on active sodium transport, stimulated by cyclic nucleotides across the frog skin in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374692"}
{"pmid": "4374703", "title": "Production of herpes simplex antisera with increased type specificity in guinea pigs by antibody suppression.", "content": "Production of herpes simplex antisera with increased type specificity in guinea pigs by antibody suppression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374703"}
{"pmid": "4374704", "title": "Effects of glucagon upon rat liver mitochondria in vivo.", "content": "Effects of glucagon upon rat liver mitochondria in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374704"}
{"pmid": "4374693", "title": "Infectious diseases: annual review of significant publications.", "content": "Infectious diseases: annual review of significant publications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374693"}
{"pmid": "4374706", "title": "Angiotensin antagonist and possible release of catecholamine.", "content": "Angiotensin antagonist and possible release of catecholamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374706"}
{"pmid": "4374707", "title": "Irreversible inhibition of angiotensin II activity on the rat uterus by an alkylating angiotensin derivative.", "content": "Irreversible inhibition of angiotensin II activity on the rat uterus by an alkylating angiotensin derivative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374707"}
{"pmid": "4374708", "title": "The origin of an E.S.R signal at g equals 2.03 from normal rabbit liver and the effects of nitrites upon it.", "content": "The origin of an E.S.R signal at g equals 2.03 from normal rabbit liver and the effects of nitrites upon it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374708"}
{"pmid": "4374710", "title": "Induction of free radicals in DNA by proflavine and visible light: influence of oxygen and ionic strength.", "content": "Induction of free radicals in DNA by proflavine and visible light: influence of oxygen and ionic strength.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374710"}
{"pmid": "4374705", "title": "Hormonal stimulation of substrate utilization in brown adipose tissue of cold acclimated rats.", "content": "Hormonal stimulation of substrate utilization in brown adipose tissue of cold acclimated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374705"}
{"pmid": "4374709", "title": "A comparison of thermal neutron and gamma ray sensitivities of common TLD materials.", "content": "A comparison of thermal neutron and gamma ray sensitivities of common TLD materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374709"}
{"pmid": "4374712", "title": "REM sleep deprivation impairs bar-press acquisition in rats.", "content": "REM sleep deprivation impairs bar-press acquisition in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374712"}
{"pmid": "4374713", "title": "Determination of renin activity of kidney homogenates.", "content": "Determination of renin activity of kidney homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374713"}
{"pmid": "4374714", "title": "The cytochrome and phospholipid content of the mitochondrial membrane of the neonatal and adult rat kidney.", "content": "The cytochrome and phospholipid content of the mitochondrial membrane of the neonatal and adult rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374714"}
{"pmid": "4374711", "title": "Influence of ACTH and adrenal hormones on the amplitude and habituation of the flexor reflex.", "content": "Influence of ACTH and adrenal hormones on the amplitude and habituation of the flexor reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374711"}
{"pmid": "4374715", "title": "The metabolic activity and equipment of the mitochondrial membranes of different tissues.", "content": "The metabolic activity and equipment of the mitochondrial membranes of different tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374715"}
{"pmid": "4374718", "title": "Endocrine alterations in delirium tremens.", "content": "Endocrine alterations in delirium tremens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374718"}
{"pmid": "4374720", "title": "The influence of pituitary peptides on brain centers controlling autonomic responses.", "content": "The influence of pituitary peptides on brain centers controlling autonomic responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374720"}
{"pmid": "4374721", "title": "The ontogenetic development of hypothalamo-hypophyseal relations.", "content": "The ontogenetic development of hypothalamo-hypophyseal relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374721"}
{"pmid": "4374723", "title": "The parafasicular area as the site of action of ACTH analogs on avoidance behavior.", "content": "The parafasicular area as the site of action of ACTH analogs on avoidance behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374723"}
{"pmid": "4374722", "title": "The adrenal glands, estrogen, and the control of parturition in the guinea pig.", "content": "The adrenal glands, estrogen, and the control of parturition in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374722"}
{"pmid": "4374724", "title": "Psychobiological aspects of lactation in rats.", "content": "Psychobiological aspects of lactation in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374724"}
{"pmid": "4374725", "title": "Effects of adrenalectomy and treatments with ACTH and glucocorticoids on isolation-induced aggressive behavior in male albino mice.", "content": "Effects of adrenalectomy and treatments with ACTH and glucocorticoids on isolation-induced aggressive behavior in male albino mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374725"}
{"pmid": "4374730", "title": "Nicotine and its metabolities. IV. Formation of the nicotine analogue of DPN by pig brain DPNase.", "content": "Nicotine and its metabolities. IV. Formation of the nicotine analogue of DPN by pig brain DPNase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374730"}
{"pmid": "4374731", "title": "Effect of epinephrine and adenosine cyclic 3',5' - monophosphate on heart mitochondrial and microsomal calcium uptake.", "content": "Effect of epinephrine and adenosine cyclic 3',5' - monophosphate on heart mitochondrial and microsomal calcium uptake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374731"}
{"pmid": "4374732", "title": "Adrenergic subsensitivity of the rat brain during chronic ethanol ingestion.", "content": "Adrenergic subsensitivity of the rat brain during chronic ethanol ingestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374732"}
{"pmid": "4374733", "title": "The increase of cyclic AMP in rat's brain during anoxia.", "content": "The increase of cyclic AMP in rat's brain during anoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374733"}
{"pmid": "4374734", "title": "Experimental infection of sheep with a type 3 reovirus of ovine origin.", "content": "Experimental infection of sheep with a type 3 reovirus of ovine origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374734"}
{"pmid": "4374741", "title": "Adenocarcinoma of the lung 101 cases including 32 cases of bronchiolar cell carcinoma. A histopathological study.", "content": "Adenocarcinoma of the lung 101 cases including 32 cases of bronchiolar cell carcinoma. A histopathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374741"}
{"pmid": "4374742", "title": "Short-term psychiatric care from a theoretical planning and empirical point of view.", "content": "Short-term psychiatric care from a theoretical planning and empirical point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374742"}
{"pmid": "4374745", "title": "Cellular mode of action of diuretics.", "content": "Cellular mode of action of diuretics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374745"}
{"pmid": "4374764", "title": "Genetic bases of the UV resistance of Salmonella. Communication II. uvrB-mutants of Salmonella abony.", "content": "Genetic bases of the UV resistance of Salmonella. Communication II. uvrB-mutants of Salmonella abony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374764"}
{"pmid": "4374762", "title": "The impact of scientific models on clinical psychopharmacology: an internist's view.", "content": "The impact of scientific models on clinical psychopharmacology: an internist's view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374762"}
{"pmid": "4374763", "title": "Origin of recessive lethal mutations suppressed by the Y chromosome in Drosophila melanogaster under the influence of radiation and ethyl methanesulfonate.", "content": "Origin of recessive lethal mutations suppressed by the Y chromosome in Drosophila melanogaster under the influence of radiation and ethyl methanesulfonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374763"}
{"pmid": "4374765", "title": "Blood groups of the ABO system and the relationship to certain malignant tumors in children.", "content": "Blood groups of the ABO system and the relationship to certain malignant tumors in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374765"}
{"pmid": "4374767", "title": "Paraphysial cysts of the third ventricle.", "content": "Paraphysial cysts of the third ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374767"}
{"pmid": "4374766", "title": "Seventeen cases of hepatectomy.", "content": "Seventeen cases of hepatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374766"}
{"pmid": "4374768", "title": "Primary liver cancer rate and aflatoxin intake in a high cancer area.", "content": "Primary liver cancer rate and aflatoxin intake in a high cancer area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374768"}
{"pmid": "4374769", "title": "Effect of protein energy malnutrition on the renal function and extracellular fluid volume of the rat.", "content": "Effect of protein energy malnutrition on the renal function and extracellular fluid volume of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374769"}
{"pmid": "4374770", "title": "Metabolic effect of conjugated oestrogens (USP) on glucose tolerance.", "content": "Metabolic effect of conjugated oestrogens (USP) on glucose tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374770"}
{"pmid": "4374775", "title": "Effects of dibutyryl cyclic AMP on contractile performance of isolated heart muscle depressed by thiamylal and halothane.", "content": "Effects of dibutyryl cyclic AMP on contractile performance of isolated heart muscle depressed by thiamylal and halothane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374775"}
{"pmid": "4374776", "title": "Effects of dibutyryl cyclic AMP on the pulmonary hemodynamics.", "content": "Effects of dibutyryl cyclic AMP on the pulmonary hemodynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374776"}
{"pmid": "4374780", "title": "A study on the stability of an estrogen-protein conjugate in vivo and under in vitro conditions.", "content": "A study on the stability of an estrogen-protein conjugate in vivo and under in vitro conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374780"}
{"pmid": "4374781", "title": "Studies on the metabolism of steroid hormones. Part II. Reversible steroid-protein interactions via enol intermediates.", "content": "Studies on the metabolism of steroid hormones. Part II. Reversible steroid-protein interactions via enol intermediates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374781"}
{"pmid": "4374785", "title": "Human prostatic carcinoma in cell culture: preliminary report on the development and characterization of an epithelial cell line (EB 33).", "content": "Human prostatic carcinoma in cell culture: preliminary report on the development and characterization of an epithelial cell line (EB 33).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374785"}
{"pmid": "4374789", "title": "The tonsils in the pathogenesis of disease.", "content": "The tonsils in the pathogenesis of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374789"}
{"pmid": "4374790", "title": "International control of equine infectious diseases.", "content": "International control of equine infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374790"}
{"pmid": "4374791", "title": "Pox in racing pigeons.", "content": "Pox in racing pigeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374791"}
{"pmid": "4374792", "title": "Infection of chicks with infectious bursal disease and its effect on the carrier state with Newcastle disease virus.", "content": "Infection of chicks with infectious bursal disease and its effect on the carrier state with Newcastle disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374792"}
{"pmid": "4374799", "title": "Unusual glomerular change in cytomegalic inclusion disease.", "content": "Unusual glomerular change in cytomegalic inclusion disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374799"}
{"pmid": "4374800", "title": "Cardiac muscle cell damage induced by restraint stress.", "content": "Cardiac muscle cell damage induced by restraint stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374800"}
{"pmid": "4374798", "title": "Evidence for B-cell origin of reticulum cell sarcoma.", "content": "Evidence for B-cell origin of reticulum cell sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374798"}
{"pmid": "4374802", "title": "Skeletal maturity of children 6-11 years, United States.", "content": "Skeletal maturity of children 6-11 years, United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374802"}
{"pmid": "4374836", "title": "Infectious mononucleosis at the United States Military Academy. A prospective study of a single class over four years.", "content": "Infectious mononucleosis at the United States Military Academy. A prospective study of a single class over four years. A prospective study of EB virus infections was initiated in July, 1969 in the entering class of 1401 cadets, at the U.S. Military Academy at West Point, N.Y. and continued over 4 yr. On entry 63.5% possessed EBV antibody and 36.5 lacked EBV antibody. The rate of antibody prevalence varied with the geographic area from which the cadet originated.Except in two cadets already ill on first bleeding no evidence of clinical infectious mononucleosis (I.M.) occurred over the 4 yr period in the 890 cadets entering the Academy with EBV antibody. Among 437 cadets without antibody on entry, 54 or 12.4% were infected (seroconverted) in the freshman year; 15 of these had clinical I.M., 12 had suggestive I.M., and 39 had no known mono-like illness. The annual infection rates in susceptible cadets in the second, third, and fourth years were 24.4, 15.1, and 30.8 per 100, respectively. Of 201 cadets infected with EBV over 4 yr only 26.4% were manifested by heterophile positive clinical infectious mononucleosis. Overall, 46% of the 437 cadets entering without EBV antibody became infected over 40 mo of serologic observation; definite clinical infectious mononucleosis developed in 53 cadets, a clinical attack rate of 12.1 per 100 for 4 yr. The EBV infection rate among exposed and susceptible roommates of known cases was no higher than in roommates not so exposed.Elevations of EBV-specific and total IgM occurred during acute illness and disappeared in late convalescence. Total IgG and IgA levels were less commonly elevated. EBV-specific-IgM antibody was demonstrable during the acute illness but was absent 12 mo later. Analysis of EBV infection rates revealed no difference among persons of different ABO blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374836"}
{"pmid": "4374850", "title": "Microscopic findings in the lungs of calves aerosolized with Pasteurella hemolytica and treated to alter pulmonary clearance.", "content": "Microscopic findings in the lungs of calves aerosolized with Pasteurella hemolytica and treated to alter pulmonary clearance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374850"}
{"pmid": "4374851", "title": "The effect of azetidine-2-carboxylic acid on the biosynthesis of collagen in rat granuloma.", "content": "The effect of azetidine-2-carboxylic acid on the biosynthesis of collagen in rat granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374851"}
{"pmid": "4374852", "title": "Biochemical studies on some new analogues of adenosine-3'5'-cyclic phosphate, including isoguanosine-3 ,5-cylic phosphate.", "content": "Biochemical studies on some new analogues of adenosine-3'5'-cyclic phosphate, including isoguanosine-3 ,5-cylic phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374852"}
{"pmid": "4374854", "title": "Trauma: hormonal factors with special reference to diabetes mellitus.", "content": "Trauma: hormonal factors with special reference to diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374854"}
{"pmid": "4374855", "title": "Normal carbohydrate metabolism and carbohydrate metabolism in trauma.", "content": "Normal carbohydrate metabolism and carbohydrate metabolism in trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374855"}
{"pmid": "4374856", "title": "Metabolism of alcohol.", "content": "Metabolism of alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374856"}
{"pmid": "4374857", "title": "General metabolic response to trauma including pain influence.", "content": "General metabolic response to trauma including pain influence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374857"}
{"pmid": "4374858", "title": "Effects of triparanol and 20,25-diazacholesterol in CNS of rat: morphological and biochemical studies.", "content": "Effects of triparanol and 20,25-diazacholesterol in CNS of rat: morphological and biochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374858"}
{"pmid": "4374859", "title": "The fine structural localisation of thiamine pyrophosphatase and adenosine triphosphatase in neural tumours induced by N-ethyl-N-nitrosourea in rats.", "content": "The fine structural localisation of thiamine pyrophosphatase and adenosine triphosphatase in neural tumours induced by N-ethyl-N-nitrosourea in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374859"}
{"pmid": "4374861", "title": "Hypertrophic neuropathy in a dog.", "content": "Hypertrophic neuropathy in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374861"}
{"pmid": "4374860", "title": "Fatal polymyositis: morphogenesis and ultrastructural features.", "content": "Fatal polymyositis: morphogenesis and ultrastructural features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374860"}
{"pmid": "4374853", "title": "The estrogen test: an aid in differential cytodiagnosis.", "content": "The estrogen test: an aid in differential cytodiagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374853"}
{"pmid": "4374862", "title": "Glioblastoma multiforme of the medulla oblangata.", "content": "Glioblastoma multiforme of the medulla oblangata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374862"}
{"pmid": "4374863", "title": "Histochemically demonstrable non-specific cholinesterase as an indicator of peripheral nerve lesion in carbon disulphide-induced polyneuropathy.", "content": "Histochemically demonstrable non-specific cholinesterase as an indicator of peripheral nerve lesion in carbon disulphide-induced polyneuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374863"}
{"pmid": "4374866", "title": "Physical development and performance capacity in a group of diabetic children and adolescents.", "content": "Physical development and performance capacity in a group of diabetic children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374866"}
{"pmid": "4374867", "title": "Relationship between biological age, habitual physical activity and morphological, physiological characteristics of 12 and 13 year old boys.", "content": "Relationship between biological age, habitual physical activity and morphological, physiological characteristics of 12 and 13 year old boys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374867"}
{"pmid": "4374865", "title": "Spino-olivo-ponto-cerebello-nigral atrophy with Lewy bodies and binucleated nerve cells: a case report.", "content": "Spino-olivo-ponto-cerebello-nigral atrophy with Lewy bodies and binucleated nerve cells: a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374865"}
{"pmid": "4374868", "title": "Skeletal maturation and physical fitness of 12 to 15 year old boys.", "content": "Skeletal maturation and physical fitness of 12 to 15 year old boys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374868"}
{"pmid": "4374869", "title": "Anthropometrical data, muscle-strength, physiological and selected motor ability factors of 11 year old boys.", "content": "Anthropometrical data, muscle-strength, physiological and selected motor ability factors of 11 year old boys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374869"}
{"pmid": "4374870", "title": "Geographical pathology of gastric carcinoma.", "content": "Geographical pathology of gastric carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374870"}
{"pmid": "4374871", "title": "The permeability pathways in the walls of intesinal submucosal arterioles in acute angiotensin-induced hypertension in rats.", "content": "The permeability pathways in the walls of intesinal submucosal arterioles in acute angiotensin-induced hypertension in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374871"}
{"pmid": "4374873", "title": "Multicentric and bilateral appearance of lobular carcinoma in situ of the breast.", "content": "Multicentric and bilateral appearance of lobular carcinoma in situ of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374873"}
{"pmid": "4374872", "title": "Ultrastructural pathological changes in intestinal submucosal arterioles in angiotensin-induced acute hypertension in rats.", "content": "Ultrastructural pathological changes in intestinal submucosal arterioles in angiotensin-induced acute hypertension in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374872"}
{"pmid": "4374874", "title": "Concentrations of renin and renin substrate in plasma of rabbits during pregnancy and the post partum period.", "content": "Concentrations of renin and renin substrate in plasma of rabbits during pregnancy and the post partum period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374874"}
{"pmid": "4374875", "title": "Renin inactivation in vitro in pregnant and post partum rabbit uterine and kidney tissue.", "content": "Renin inactivation in vitro in pregnant and post partum rabbit uterine and kidney tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374875"}
{"pmid": "4374876", "title": "The ability of various insulins and insulin fragments to inhibit the angiotensin I converting enzyme.", "content": "The ability of various insulins and insulin fragments to inhibit the angiotensin I converting enzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374876"}
{"pmid": "4374877", "title": "Effects of ACTH and HCG on ovarian oestrogen and progesterone secretion in dogs pretreated with HCG.", "content": "Effects of ACTH and HCG on ovarian oestrogen and progesterone secretion in dogs pretreated with HCG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374877"}
{"pmid": "4374880", "title": "Human herpes simplex virus infections.", "content": "Human herpes simplex virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374880"}
{"pmid": "4374882", "title": "Slow infections of the nervous system and the subacute spongiform encephalopathies.", "content": "Slow infections of the nervous system and the subacute spongiform encephalopathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374882"}
{"pmid": "4374881", "title": "Viral infections of the developing nervous system.", "content": "Viral infections of the developing nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374881"}
{"pmid": "4374883", "title": "Progressive multifocal leukoencephalopathy.", "content": "Progressive multifocal leukoencephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374883"}
{"pmid": "4374884", "title": "Advances in diagnosis and treatment of solid tumors in children.", "content": "Advances in diagnosis and treatment of solid tumors in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374884"}
{"pmid": "4374886", "title": "Effects of \"Bordetella pertussis\" on hemic colony-forming cells and immune response.", "content": "Effects of \"Bordetella pertussis\" on hemic colony-forming cells and immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374886"}
{"pmid": "4374887", "title": "The Tecumseh study of respiratory illness. VII. Further observations on the occurrence of respiratory syncytial virus and Mycoplasma pneumoniae infections.", "content": "The Tecumseh study of respiratory illness. VII. Further observations on the occurrence of respiratory syncytial virus and Mycoplasma pneumoniae infections. The occurrence of infection with respiratory syncytial (RS) virus and Mycoplasma pneumoniae was determined over a 6-year period among residents of Tecumseh, Michigan by isolation and serology. RS virus infection was detected for a variable time each year during the months extending from November to May. There was little viral activity in intervals between these periods of prevalence, which occurred on an alternating short-long cycle. Higher infection rates were detected in periods preceding the long interval than were detected in periods preceding the short interval. Viruses isolated from serial annual outbreaks did not show any sequential changes in antigens, although some variation in antigenic structure was apparent. Infections were common in school-age children, indicating the role of this population in transmission. Young girls were infected as often as young boys, suggesting that observed differences in occurrence of illness must be related to differences in expression of infection. In contrast to RS virus, M. pneumoniae did not appear and disappear annually, but like it, the school-age group was most heavily involved in infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374887"}
{"pmid": "4374888", "title": "The malignant cell and its membranes.", "content": "The malignant cell and its membranes. In this brief review the hypothesis that altered membrane proteins and glycoproteins may be critical mediators of malignant expression is discussed. Examples of alterations of membrane proteins in malignancy are presented. Data is summarized showing changes in the carbohydrate components of glycoproteins of surface and internal membranes of malignant cells in culture as compared to their normal counterparts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374888"}
{"pmid": "4374885", "title": "Regulation of lysosomal enzyme secretion: role in inflammation.", "content": "Regulation of lysosomal enzyme secretion: role in inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374885"}
{"pmid": "4374890", "title": "Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion.", "content": "Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion. A23187 is an antibiotic ionophore which transports divalent cations across cell membranes into the cytoplasm and releases cations from intracellular storage sites. The present investigation has studied the influence of A23187 on blood platelet aggregation and secretion. A23187 added to stirred C-PRP produced concentration-dependent aggregation and release of (14)C-serotonin. Calcium ions potentiated the response of platelets in washed suspensions to A23187, but they were not required for ionophore-induced aggregation or release. N-ethylmaleimide and agents which increase the level of cyclic 3',5'-adenosine monophosphate (cAMP) in platelets were effective inhibitors of A23187-induced aggregation and secretion.Platelets incubated with (45)Ca(++) before addition of A23187 increased their content of isotope by 50% within 45 seconds after exposure to the ionophore. The results indicate that an increase in the cytoplasmic concentration of calcium ions from intracellular sources may be the critical event in triggering platelet contraction and the release reaction. Increased concentrations of cAMP may inhibit the platelet response to A23187 and other aggregating agents by stimulating a calcium extrusion pump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374890"}
{"pmid": "4374894", "title": "Acute cyanide poisoning.", "content": "Acute cyanide poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374894"}
{"pmid": "4374889", "title": "Are viruses important in carcinogenesis?", "content": "Are viruses important in carcinogenesis? The role of viruses in the etiology of animal cancers is fairly certain. Information derived under both natural and experimental conditions supports the concept that either DNA- or RNA-containing viruses can fulfill this function. The DNA-containing herpesviruses, especially the Epstein-Barr virus, are currently the primary objects of intense investigation concerning their role in human cancer. This article will focus on the properties of counterpart herpesviruses in lower animals as well as the human virus candidates with an assessment of the observations concerning their oncogenic potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374889"}
{"pmid": "4374898", "title": "Excretion of individual adrenocortical steroids in obese children.", "content": "Excretion of individual adrenocortical steroids in obese children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374898"}
{"pmid": "4374899", "title": "Infantile rickets with server proximal renal tubular acidosis, responsive to vitamin D.", "content": "Infantile rickets with server proximal renal tubular acidosis, responsive to vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374899"}
{"pmid": "4374900", "title": "Thyrotoxic myopathy.", "content": "Thyrotoxic myopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374900"}
{"pmid": "4374901", "title": "Nuclear and cytoplasmic inclusions in normal human epidermis.", "content": "Nuclear and cytoplasmic inclusions in normal human epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374901"}
{"pmid": "4374902", "title": "The chemotherapy of rodent malaria. XX. Autophagic vacuole formation in Plasmodium berghei in vitro.", "content": "The chemotherapy of rodent malaria. XX. Autophagic vacuole formation in Plasmodium berghei in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374902"}
{"pmid": "4374903", "title": "Ultrastructure of the bloodstream forms of an avian trypanosome Trypanosoma bouffardi.", "content": "Ultrastructure of the bloodstream forms of an avian trypanosome Trypanosoma bouffardi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374903"}
{"pmid": "4374907", "title": "Nuclear inclusions in lutein cells of pregnant rats.", "content": "Nuclear inclusions in lutein cells of pregnant rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374907"}
{"pmid": "4374908", "title": "Electron microscopic studies on dog testicular interstitial cells.", "content": "Electron microscopic studies on dog testicular interstitial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374908"}
{"pmid": "4374913", "title": "The effects of alizarin red S on weight gain and skull growth in the rat.", "content": "The effects of alizarin red S on weight gain and skull growth in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374913"}
{"pmid": "4374914", "title": "The chemical composition and some structural features of the principal salivary glycoprotein isolated from human mixed saliva.", "content": "The chemical composition and some structural features of the principal salivary glycoprotein isolated from human mixed saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374914"}
{"pmid": "4374915", "title": "Use of specifically labelled sucrose for the quantitative assay of levansucrase activity.", "content": "Use of specifically labelled sucrose for the quantitative assay of levansucrase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374915"}
{"pmid": "4374916", "title": "Adenoid cystic carcinoma of the maxilla.", "content": "Adenoid cystic carcinoma of the maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374916"}
{"pmid": "4374917", "title": "Refractile granular inclusions in a temperature-sensitive mutant of Escherichia coli K-12.", "content": "Refractile granular inclusions in a temperature-sensitive mutant of Escherichia coli K-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374917"}
{"pmid": "4374918", "title": "studies of plasma bradykininases using radiolabelled substrates.", "content": "studies of plasma bradykininases using radiolabelled substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374918"}
{"pmid": "4374919", "title": "Diabetes mellitus--a membrane receptor defect.", "content": "Diabetes mellitus--a membrane receptor defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374919"}
{"pmid": "4374920", "title": "Morphological development of the lung: a review.", "content": "Morphological development of the lung: a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374920"}
{"pmid": "4374922", "title": "The prevalence of antibodies to adenoviruses in horses from queensland and New South Wales.", "content": "The prevalence of antibodies to adenoviruses in horses from queensland and New South Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374922"}
{"pmid": "4374921", "title": "Equine herpesviruses. 5. Epizootiology of slowly cytopathic viruses in foals.", "content": "Equine herpesviruses. 5. Epizootiology of slowly cytopathic viruses in foals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374921"}
{"pmid": "4374923", "title": "Mammary and extramammary Paget's disease.", "content": "Mammary and extramammary Paget's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374923"}
{"pmid": "4374924", "title": "The mode of action of steroid hormones: some recent findings.", "content": "The mode of action of steroid hormones: some recent findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374924"}
{"pmid": "4374925", "title": "Progesterone-Progestin receptors.", "content": "Progesterone-Progestin receptors. A correlation between binding to the progestin-specific uterine cytosol receptor and with well-defined facets of progesterone action was established. Structurally similar derivatives of norprogesterone and nortestosterone were compared.  Binding was measured in vitro by determining their competitive effect on the progestin-tagged uterine cytosol receptor of the rabbit and mouse. Activity in vivo was measured by determining their ability to induce endometrial proliferation in  the rabbit and their inhibitory effect on the estradiol-induced uterine weight increase in the mouse. Immature female Normandy rabbits, Hartley guinea pigs, immature female Swiss SPF mice, and Sprague-Dawley SPF rats were used. Groups of 5  rabbits were primed from Days 1 to 5 by daily injections of 5 mcg estradiol. Progesterone, or a test compound, was injected from Days 6 to 10. On Day 11 the rabbits were sacrificed and the endometrium prepared for histological examination.  The relative potency of each steroid was compared with that of progesterone for the rabbit.  Groups of 4 mice received daily injections of .09 mcg estradiol and various doses of progesterone or test compounds. These animals were sacrificed 24 hours after the last doses and their uteri excised and weighed. Antiestrogenic activity was  indicated by the inhibition of uterine weight increase. The progestin specificity of the 7-8S receptor was established. The weakest competitor was progesterone. Progestins R5020, H3510, and norgestrel were highly potent. Labeled cortisol  bound in the 4-S region and served as a marker. Competition studies established that 19-nor derivatives also compete for the progesterone receptor.  Structural modifications of the norprogesterone and nortestosterone molecules modified results. The in vivo biological activity of all compounds was greater than the of progesterone. The introduction of 1 or 2 double binds into the 19-nor  molecule decreased this somewhat.  The addition of a 17 alpha-methyl substituent (H3510) to norprogesterone also decreased activity. Other modifications of the molecules also changed activity. Results of antiestrogenic activity in the mouse showed that norprogesterone was  markedly more active than progesterone.  Antiestrogenic activity and binding were correlated in the case of all the monoenes (norprogesterone and H3510) and denies (H3163 and R2453). A perfect correlation was observed between binding in the rabbit and the mouse for the 12 test  compounds. The search for highly potent progestins involves, as an initial step, the search for a compound that binds tightly to the 7-8S receptor. In vivo extraneous factors may also become critical. Only by measuring antiestrogenic activity  and progestomimetic activity in the same species can the existence, or lack of existence, of a correlation be established.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374925"}
{"pmid": "4374926", "title": "Endocrine control of spermatogenesis.", "content": "Endocrine control of spermatogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374926"}
{"pmid": "4374928", "title": "Protein synthesis machinery in growing oocytes of mice.", "content": "Protein synthesis machinery in growing oocytes of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374928"}
{"pmid": "4374927", "title": "Mechanism of action of luteinizing hormone-releasing hormone.", "content": "Mechanism of action of luteinizing hormone-releasing hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374927"}
{"pmid": "4374929", "title": "The ultrastructure of Malignant Synovioma.", "content": "The ultrastructure of Malignant Synovioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374929"}
{"pmid": "4374930", "title": "Leaf peroxidase activities in tomato mutants affecting plant morphology.", "content": "Leaf peroxidase activities in tomato mutants affecting plant morphology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374930"}
{"pmid": "4374932", "title": "Identification of N-acetyl-4-O-acetylneuraminyl-lactose in Echidna milk.", "content": "Identification of N-acetyl-4-O-acetylneuraminyl-lactose in Echidna milk. The identity of a novel form of sialyl-lactose found in milk of the echidna (Tachyglossus aculeatus) was investigated. The sialyl-lactose yielded equimolar amounts of N-acetylneuraminic acid and lactose during mild acid hydrolysis but was resistant to the action of a bacterial neuraminidase. A viral neuraminidase hydrolysed it to lactose plus a form of sialic acid that reacted positively with thiobarbituric acid reagent but whose chromatographic mobility was greater than that of N-acetylneuraminic acid. Treatment with alkali converted the sialyl-lactose into a substance with the same chromatographic mobility as N-acetylneuraminyl-(2-->3)-lactose and made it susceptible to the action of bacterial neuraminidase. The sialyl-lactose contained one mol of ester (identified as acetyl), and released one mol of formaldehyde during periodate oxidation, per mol of sialic acid. It did not contain N-glycollylneuraminic acid. These results indicate that the sialyl-lactose is N-acetyl-4-O-acetylneuraminyl-(2-->3)-lactose. Echidna milk contained, in addition, a small amount of N-acetylneuraminyl-(2-->3)-lactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374932"}
{"pmid": "4374931", "title": "The interaction of alpha2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases.", "content": "The interaction of alpha2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases. 1. Experiments were performed to determine whether the specific collagenases and other metal proteinases are bound and inhibited by alpha(2)-macroglobulin, as are endopeptidases of other classes. 2. A specific collagenase from rabbit synovial cells was inhibited by human serum. The inhibition could be attributed entirely to alpha(2)-macroglobulin; alpha(1)-trypsin inhibitor was not inhibitory. alpha(2)-Macroglobulin presaturated with trypsin or cathepsin B1 did not inhibit collagenase, and pretreatment of alpha(2)-macroglobulin with collagenase prevented subsequent reaction with trypsin. The binding of collagenase by alpha(2)-macroglobulin was not reversible in gel chromatography. 3. The collagenolytic activity of several rheumatoid synovial fluids was completely inhibited by incubation of the fluids with alpha(2)-macroglobulin. 4. The collagenase of human polymorphonuclear-leucocyte granules showed time-dependent inhibition by alpha(2)-macroglobulin. 5. The collagenolytic metal proteinase of Crotalus atrox venom was inhibited by alpha(2)-macroglobulin. 6. The collagenase of Clostridium histolyticum was bound by alpha(2)-macroglobulin, and inhibited more strongly with respect to collagen than with respect to a peptide substrate. 7. Thermolysin, the metal proteinase of Bacillus thermoproteolyticus, was bound and inhibited by alpha(2)-macroglobulin. 8. It was shown by polyacrylamidegel electrophoresis of reduced alpha(2)-macroglobulin in the presence of sodium dodecyl sulphate that synovial-cell collagenase, clostridial collagenase and thermolysin cleave the quarter subunit of alpha(2)-macroglobulin near its mid-point, as do serine proteinases. 9. The results are discussed in relation to previous work, and it is concluded that the characteristics of interaction of the metal proteinases with alpha(2)-macroglobulin are the same as those of other proteinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374931"}
{"pmid": "4374933", "title": "Biospecific affinity chromatography of an adenosine 3':5'-cyclic monophosphate-stimulated protein kinase (protamine kinase from trout testis) by using immobilized adenine nucleotides.", "content": "Biospecific affinity chromatography of an adenosine 3':5'-cyclic monophosphate-stimulated protein kinase (protamine kinase from trout testis) by using immobilized adenine nucleotides. 1. Two adenine nucleotides, 8-(6-aminohexyl)aminoadenosine 3':5'-cyclic monophosphate and 8-(6-aminohexyl)amino-AMP, were synthesized. Their structures were established in particular by using mass spectroscopy. 2. Free cyclic AMP and 8-(6-aminohexyl)amino cyclic AMP both stimulate protamine kinase activity at low concentrations, but are inhibitory at concentrations above 0.1mm. AMP is an inhibitor of enzymic activity, whereas neither 8-(6-aminohexyl)amino-AMP nor the earlier synthesized N(6)-(6-aminohexyl)-AMP is inhibitory. 3. The nucleotides were coupled to Sepharose 4B and used for biospecific chromatography of partially purified protamine kinase. Enzyme applied at high buffer concentrations to the cyclic AMP-Sepharose material was retarded and thereby purified tenfold. At low buffer concentrations the enzyme was adsorbed to the affinity material, and was subsequently released by a pulse of the inhibitor AMP, yielding a 50-100-fold purification. Enzyme applied to immobilized 8-(6-aminohexyl)amino-AMP or N(6)-(6-aminohexyl)-AMP was eluted together with the main protein peak in the void volume. 4. Protamine kinase eluted from 8-(6-aminohexyl)amino cyclic AMP-Sepharose was no longer activated by cyclic AMP. Results from sucrose gradient centrifugation suggest that a dissociation of the enzyme took place on the immobilized nucleotide. 5. Further information on the mass spectroscopy has been deposited as Supplementary Publication SUP 50026 at the British Library (Lending Division) (formerly the National Lending Library for Science and Technology), Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained on the terms given in Biochem. J. (1973) 131, 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374933"}
{"pmid": "4374934", "title": "The purification and amino acid sequence of cytochrome C-552 from Euglena gracilis.", "content": "The purification and amino acid sequence of cytochrome C-552 from Euglena gracilis. Cytochrome c-552 from Euglena gracilis was purified and the amino acid sequence determined. The protein is a single peptide chain of 87 residues with the haem prosthetic group bound through two thioether linkages to two cysteine residues near the amino-terminal region. The amino acid sequence shows some similarities to mitochondrial cytochrome c and to two prokaryote c-type cytochromes. The sequence, taken with the known characteristics of cytochrome c-552, indicates that it is an f-type cytochrome. The possible functional and evolutionary significance of these features in common is discussed. Detailed evidence for the amino acid sequence of Euglena cytochrome f has been deposited as Supplementary Publication SUP 50027 at the British Library, Lending Division (formerly the National Lending Library for Science and Technology), Boston Spa, Yorks. LS23 7QB, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1973) 131, 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374934"}
{"pmid": "4374935", "title": "Hepatic drug hydroxylation and lipid peroxidation in riboflavin-deficient rats.", "content": "Hepatic drug hydroxylation and lipid peroxidation in riboflavin-deficient rats. The effect of riboflavin deficiency and phenobarbital pretreatment on drug hydroxylation and lipid peroxidation was investigated. A significant decrease in aniline and acetanilide hydroxylation as well as NADPH-linked and ascorbate-induced lipid peroxidation was observed during 4- and 7-week riboflavin deficiency in both adult male and adult female rats. The drug-hydroxylation and lipid-peroxidation activities were further lowered with the increase in riboflavin deficiency. The phenobarbital pretreatment induced aniline and acetanilide hydroxylase activity even in riboflavin-deficient animals. Drug hydroxylation inhibits lipid peroxidation in both deficient and normal rats. The administration of riboflavin was followed by a significant increase in drug hydroxylation and lipid peroxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374935"}
{"pmid": "4374936", "title": "The concentration and control of cytoplasmic free inorganic pyrophosphate in rat liver in vivo.", "content": "The concentration and control of cytoplasmic free inorganic pyrophosphate in rat liver in vivo. The concentration of cytoplasmic free pyrophosphate was calculated in freeze-clamped livers of rats from the measured concentration of reactants and K(eq.) of the UDP-glucose pyrophosphorylase reaction (UDP-alpha-d-glucose 1-phosphate uridylyltransferase, EC 2.7.7.9). The K(eq.) of the UDP-glucose pyrophosphorylase reaction was redetermined at 38 degrees C, pH7.0, I=0.25mol/l and free [Mg(2+)]=1mm, and was 4.55 in the direction of glucose 1-phosphate formation. The activity of UDP-glucose pyrophosphorylase in rat liver was between 46 and 58mumol of glucose 1-phosphate formed/min per g fresh wt. in the four dietary conditions studied. A fluorimetric assay with enzymic cycling was developed for the measurement of glucose 1-phosphate in HClO(4) extracts of rat liver. The calculated free cytoplasmic PP(i) concentration in nmol/g fresh wt. of liver was 2.3+/-0.3 in starved, 3.8+/-0.4 in fed, 4.9+/-0.6 in meal-fed and 5.2+/-0.4 in sucrose-re-fed animals. These values agree well with recently determined direct measurements of total PP(i) in rat liver and suggest that there is not a large amount of bound or metabolically inert PP(i) in rat liver. The cytoplasmic [ATP]/[AMP][PP(i)] ratio is 10(3) times the cytoplasmic [ATP]/[ADP][P(i)] ratio and varies differently with dietary state. The reaction PP(i)+H(2)O-->2P(i) catalysed by inorganic pyrophosphatase (EC 3.6.1.1) does not attain near-equilibrium in vivo. PP(i) should be considered as one of the group of small inorganic ions which is metabolically active and capable of exerting a controlling function in a number of important metabolic reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374936"}
{"pmid": "4374938", "title": "Requirement for adenosine triphosphate for stimulation in vitro of ox growth-hormone release.", "content": "Requirement for adenosine triphosphate for stimulation in vitro of ox growth-hormone release. Rotenone, carbonyl cyanide chloromethoxyphenylhydrazone and 2,4-dinitrophenol cause parallel falls in ox pituitary ATP content and growth-hormone release in the presence of 65mm-K(+). Carbonyl cyanide chloromethoxyphenylhydrazone (0.4mug/ml) prevented the rise in growth-hormone release, but not the rise in 3':5'-cyclic AMP content after addition of prostaglandin E(2) (1mug/ml). The rate of hormone release from unstimulated slices and from slices in the presence of Ba(2+) at 2.3 or 6.9mm was proportional to the ATP content of the slices. Carbonyl cyanide chloromethoxyphenylhydrazone at concentrations that inhibited release in the presence of the three secretagogues did not alter the pituitary contents of Na(+), K(+) or Ca(2+). The implications of these observations are discussed in terms of the mechanism of stimulus-secretion coupling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374938"}
{"pmid": "4374937", "title": "The biochemistry of virus-induced cell fusion. Changes in membrane integrity.", "content": "The biochemistry of virus-induced cell fusion. Changes in membrane integrity. 1. Phospholipids prelabelled with [(14)C]acetate, [(32)P]phosphate, [(3)H]- or [(14)C]-choline or [(3)H]inositol are not significantly degraded during fusion of Lettrée cells mediated by Sendai virus, nor are carbohydrates prelabelled with [(3)H]fucose, [(14)C]galactose or [(3)H]glucosamine. Less than 1nmol of lysophosphatidylcholine/10(7) cells is formed during fusion. Diethyl p-nitrophenyl phosphate, which inhibits phospholipase A by more than 95% has no effect on fusion. It is concluded that none of the events leading to cell fusion is accompanied by significant turnover of phospholipids or other membrane components. 2. Intracellular K(+) leaks out during virally mediated cell fusion; the loss is not as extensive as that of intracellularly accumulated choline or deoxyglucose. Movement of Ca(2+) into or out of cells could not be detected. 3. At concentrations of Lettrée cells insufficient to be agglutinated by virus, intracellularly accumulated choline and deoxyglucose leak out. Agglutination caused by concanavalin A does not result in leakage of intracellular metabolites. 4. P815Y cells, which agglutinate but do not fuse in the presence of virus, show leakage of intracellularly accumulated metabolites. The extent of leakage does not alter during the G(1) and S periods of the cell cycle. 5. Leakage is inhibited by Ca(2+), but is unaffected by EDTA. 6. It is concluded that the interaction of Sendai virus with mammalian cells causes a weakening of membrane integrity so that intracellular metabolites leak out. Such destabilization may facilitate viral entry and is therefore an interesting system for further biochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374937"}
{"pmid": "4374940", "title": "High-affinity binding of oestradiol-17beta by cytosols from testis interstitial tissue, pituitary, adrenal, liver and accessory sex glands of the male rat.", "content": "High-affinity binding of oestradiol-17beta by cytosols from testis interstitial tissue, pituitary, adrenal, liver and accessory sex glands of the male rat. The specificity of the binding of oestradiol-17beta by cytoplasmic fractions of several tissues of the male rat was investigated. 1. Agar-gel electrophoresis, Sephadex chromatography, adsorption by dextran-coated charcoal and sucrose-gradient centrifugation were used to estimate the binding capacity and specificity. The four different methods all gave similar results for the capacity of the specific oestradiol-17beta-binding macromolecules in the testis. 2. The presence of a specific saturable binding protein with a sedimentation coefficient of 8S was demonstrated in liver, adrenal, pituitary, prostate, epididymis and testis interstitial tissue. The highest concentration of oestradiol-17beta-binding macromolecules was found in testis interstitial tissue (0.12pmol/mg of protein) and in the pituitary (0.075pmol/mg of protein). 3. The oestradiol-17beta receptor in the testis cytosol showed the characteristics of a protein with respect to Pronase treatment and temperature sensitivity. In competition experiments with different steroids the receptor showed a high affinity for oestradiol-17beta, a moderate affinity for diethylstilboestrol and oestradiol-17alpha and a low affinity for oestrone, oestriol, testosterone and 5alpha-dihydrotestosterone (17beta-hydroxy-5alpha-androstan-3-one). 4. The wide distribution of oestradiol-17beta receptors in the male rat is in apparent contradiction to the current concept of the specificity of steroid-hormone action. Further research is required to investigate a possible physiological meaning of the presence of specific receptors in the different tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374940"}
{"pmid": "4374941", "title": "The mechanism of intestinal absorption of phosphatidylcholine in rats.", "content": "The mechanism of intestinal absorption of phosphatidylcholine in rats. 1. The mechanism of absorption of phosphatidylcholine was studied in rats by injecting into the intestine phosphatidylcholine specifically labelled either in the fatty acid or in the glycerol moiety or with (32)P, when considerable amounts of 1-acyl-lysophosphatidylcholine were found in the intestinal lumen. 2-([(14)C]Acyl)phosphatidylcholine gave markedly more radioactive unesterified fatty acids in the lumen, compared with the 1-([(14)C]acyl) derivative. Some of the radioactivity from either the fatty acid or the glycerol moiety of the injected phosphatidylcholine appeared in the mucosal triacylglycerols. 2. Injection of (32)P-labelled phosphatidylcholine or (32)P-labelled lysophosphatidylcholine led to the appearance of radioactive glycerylphosphorylcholine, glycerophosphate and P(i) in the mucosa. 3. Rat mucosa was found to contain a highly active glycerylphosphorylcholine diesterase. 4. It was concluded that the dietary phosphatidylcholine is hydrolysed in the intestinal lumen by the pancreatic phospholipase A to 1-acylglycerylphosphorylcholine, which on entering the mucosal cell is partly reacylated to phosphatidylcholine, and the rest is further hydrolysed to glycerylphosphorylcholine, glycerophosphate, glycerol and P(i). The fatty acids and glycerophosphate are then reassembled to give triacylglycerols via the Kennedy (1961) pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374941"}
{"pmid": "4374939", "title": "Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B cells with special regard to the role of nicotinamide-adenine dinucleotide.", "content": "Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B cells with special regard to the role of nicotinamide-adenine dinucleotide. The effects on the pancreatic B cell of streptozotocin and its aglucone derivative N-nitrosomethylurea were investigated in obese-hyperglycaemic mice and their lean littermates. Both streptozotocin and N-nitrosomethylurea were found to be B-cytotoxic although N-nitrosomethylurea produced less islet damage. Both substances decreased the concentrations of NAD(+) in the islet cells to about 10% of the control values within 2h after injection. This NAD(+) depletion was prevented by injection of nicotinamide 10min after the administration of streptozotocin or N-nitrosomethylurea. In islets taken from animals 10min after injection of streptozotocin or N-nitrosomethylurea there was no stimulatory effect of glucose on the respiration or insulin release and the oxidation of glucose was markedly decreased. Addition of nicotinamide (10mm) to the incubated islets restored glucose stimulation of both the oxygen consumption and insulin release. It is concluded that islet NAD(+) depletion is probably important for the B-cytotoxin action of N-nitrosomethylurea and streptozotocin. The glucose residue in the streptozotocin molecule may potentiate the B-cytotoxic action of this drug in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374939"}
{"pmid": "4374942", "title": "Involvement of binding lipoproteins in the absorption and transport of alpha-tocopherol in the rat.", "content": "Involvement of binding lipoproteins in the absorption and transport of alpha-tocopherol in the rat. 1. Specific lipoproteins binding alpha-tocopherol but not its known metabolites have been isolated and identified from cytosol of rat intestinal mucosa and from serum. 2. A timestudy of the appearance of the orally administered alpha-[(3)H]tocopherol with these lipoproteins indicates that very-low-density lipoprotein of serum acts as a carrier of the vitamin. 3. The involvement of the mucosal lipoprotein in the absorption of the vitamin from the intestine has been inferred from observations on the amounts of alpha-tocopherol in serum of orotic acid-fed rats where release of lipoproteins from the liver to serum is completely inhibited. A considerable decrease in the association of alpha-tocopherol with serum very-low-density lipoprotein under this condition is interpreted to mean that serum lipoproteins are limiting factors for the transport of the vitamin across the intestine and that this is possibly effected by exchange of alpha-tocopherol between serum very-low-density lipoprotein and mucosal lipoprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374942"}
{"pmid": "4374943", "title": "Effects of alpha-amanitin on the stimulation of prostatic ribonucleic acid polymerase by prostatic steroid-protein receptor complexes.", "content": "Effects of alpha-amanitin on the stimulation of prostatic ribonucleic acid polymerase by prostatic steroid-protein receptor complexes. Stimulation of prostatic RNA polymerase in vitro by prostatic 17beta-hydroxy-5alpha-androstan-3-one (5alpha-dihydrotestosterone)-receptor complexes has been previously reported. By use of the selective inhibitor, alpha-amanitin, we have shown that both nucleolar and extranucleolar RNA polymerase activities may be stimulated, but stimulation is abolished at high ionic strength.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374943"}
{"pmid": "4374945", "title": "Cell-free biosynthesis of polyprenyl derivatives of p-hydroxybenzoic acid in mammalian and bacterial systems.", "content": "Cell-free biosynthesis of polyprenyl derivatives of p-hydroxybenzoic acid in mammalian and bacterial systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374945"}
{"pmid": "4374944", "title": "The metabolism of phosphatidylcholine in brain tissue.", "content": "The metabolism of phosphatidylcholine in brain tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374944"}
{"pmid": "4374946", "title": "Inositol lipid metabolism and the cell membrane.", "content": "Inositol lipid metabolism and the cell membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374946"}
{"pmid": "4374947", "title": "The role of lipids in membrane structure.", "content": "The role of lipids in membrane structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374947"}
{"pmid": "4374948", "title": "Biosynthesis of unsaturated fatty acids by higher plant systems.", "content": "Biosynthesis of unsaturated fatty acids by higher plant systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374948"}
{"pmid": "4374949", "title": "Cellular control of the uptake, storage and release of noradrenaline in sympathetic nerves.", "content": "Cellular control of the uptake, storage and release of noradrenaline in sympathetic nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374949"}
{"pmid": "4374950", "title": "The influence of nerve-impulse flow on the synthesis and metabolism of 5-hydroxytryptamine in the central nervous system.", "content": "The influence of nerve-impulse flow on the synthesis and metabolism of 5-hydroxytryptamine in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374950"}
{"pmid": "4374951", "title": "The storage and release of acetylcholine by cholinergic nerve terminals: recent results with non-mammalian preparations.", "content": "The storage and release of acetylcholine by cholinergic nerve terminals: recent results with non-mammalian preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374951"}
{"pmid": "4374952", "title": "Adenosine 3':5'-cyclic monophosphate as a mediator in the action of neurohumoral agents.", "content": "Adenosine 3':5'-cyclic monophosphate as a mediator in the action of neurohumoral agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374952"}
{"pmid": "4374954", "title": "Effect of allopurinol on the synthesis of corticosterone in rat adrenals in vitro.", "content": "Effect of allopurinol on the synthesis of corticosterone in rat adrenals in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374954"}
{"pmid": "4374953", "title": "Inhibition of various cyclic AMP phosphodiesterases by pentifylline and theophylline.", "content": "Inhibition of various cyclic AMP phosphodiesterases by pentifylline and theophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374953"}
{"pmid": "4374955", "title": "Wet fallout of sulfurous pollutants emitted from a city during rain or snow.", "content": "Wet fallout of sulfurous pollutants emitted from a city during rain or snow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374955"}
{"pmid": "4374962", "title": "An unusual mandibular first molar. A case report.", "content": "An unusual mandibular first molar. A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374962"}
{"pmid": "4374963", "title": "A tumour cell aggregation promoting substance from rat ascites hepatoma cells.", "content": "A tumour cell aggregation promoting substance from rat ascites hepatoma cells. A substance capable of promoting tumour cell aggregation was released from rat ascites hepatoma cell (possibly from the cell surface) kept in Hanks' balanced salt solution (free of calcium and magnesium) in the cold, and then partially purified by chromatography with DEAE-Sephadex and gel filtration with Bio-gel. The thermostable substance seemed to be a glycoprotein and its molecular weight was about 72,000 when measured by gel filtration on Sephadex G-200. It had no proteolytic activity. The material was clearly effective for rat ascites hepatoma cells as well as SV40 transformed cells, but less effective for Chang's cells and apparently ineffective for normal rat liver cells and red blood cells. The action of this material was more potent than that of Jack bean concanavalin A when assayed for aggregation of SV40 transformed cells. Its effect was not influenced by concanavalin A inhibitors such as alpha-methyl-D-glucopyranoside, N-acetyl-D-glucosamine and D-glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374963"}
{"pmid": "4374964", "title": "Ectopic production of human chorionic gonadotrophin by human breast tumours.", "content": "Ectopic production of human chorionic gonadotrophin by human breast tumours. The incidence of tumours ectopically producing the human chorionic gonadotrophins was studied in patients with breast cancer. Specific radioimmunoassay of subunits of HCG was utilized. Nine out of 65 patients with carcinoma of breast showed the presence of circulating HCG. Patients with other pathological conditions of breast tissue did not show any evidence of circulating HCG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374964"}
{"pmid": "4374966", "title": "Dephosphorylation of rat liver ribosomal proteins by a phosphoprotein phosphatase.", "content": "Dephosphorylation of rat liver ribosomal proteins by a phosphoprotein phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374966"}
{"pmid": "4374968", "title": "Beef pancreas tryptophanyl-tRNA synthetase. Order of substrate binding in ATP-(32-P)-pyrophosphate exchange reaction.", "content": "Beef pancreas tryptophanyl-tRNA synthetase. Order of substrate binding in ATP-(32-P)-pyrophosphate exchange reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374968"}
{"pmid": "4374969", "title": "Intramitochondrial intermembranal large amplitude protein movements. I. A possible novel aspect of membrane fluidity.", "content": "Intramitochondrial intermembranal large amplitude protein movements. I. A possible novel aspect of membrane fluidity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374969"}
{"pmid": "4374971", "title": "Research of specific constraints in pair association of amino acids.", "content": "Research of specific constraints in pair association of amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374971"}
{"pmid": "4374986", "title": "Release of prostaglandins from the rabbit perfused kidney: effects of vasoconstrictors.", "content": "Release of prostaglandins from the rabbit perfused kidney: effects of vasoconstrictors. 1 The rat stomach strip was used to assay prostaglandin E(2)-like material released by a rabbit isolated kidney perfused with Krebs solution.2 Doses of noradrenaline and angiotensin II producing similar vasoconstrictor effects released equivalent amounts of prostaglandins from the kidney.3 8-Leu-angiotensin II, a specific inhibitor of the natural octapeptide, blocked the action of angiotensin II on perfusion pressure and the release of prostaglandins, while the action of noradrenaline on both parameters was unaffected.4 Indomethacin, a specific inhibitor of prostaglandin biosynthesis, blocked the effects of both vasoconstrictors on prostaglandin release while their action on perfusion pressure was significantly enhanced.5 In the kidney effluent, amounts of prostaglandin E(2)-like material increased linearly with the rise in perfusion pressure induced by increasing doses of angiotensin II. These results indicate that prostaglandin output from the isolated kidney follows the rise in perfusion pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374986"}
{"pmid": "4374987", "title": "Dissociation of 5-hydroxytryptamine effects on myocardial contractility and cyclic AMP accumulation.", "content": "Dissociation of 5-hydroxytryptamine effects on myocardial contractility and cyclic AMP accumulation. 1 5-Hydroxytryptamine increased the contractility of the isolated rat atrium and produced a small rise in cyclic 3',5'-adenosine monophosphate (cyclic AMP) accumulation in rat heart slices. These effects were similar to those of tyramine.2 Incubation with phenoxybenzamine prevented the inotropic effect of 5-hydroxytryptamine but did not inhibit the rise in cyclic AMP accumulation.3 A single injection of reserpine 24 h before the experiment did not inhibit the inotropic effect of 5-hydroxytryptamine but prevented the rise in cyclic AMP accumulation.4 It is concluded that in the rat 5-hydroxytryptamine increases cardiac contractility chiefly by a direct effect which is blocked by phenoxybenzamine, whereas it increases myocardial cyclic AMP accumulation indirectly by releasing endogenous catecholamines. Cardiac contractility may thus be increased without a rise in cyclic AMP accumulation, and cyclic AMP accumulation may be increased without a rise in contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374987"}
{"pmid": "4374989", "title": "The microbiology and sensory evaluation of pheasants hung at 5, 10 and 15 degrees C.", "content": "The microbiology and sensory evaluation of pheasants hung at 5, 10 and 15 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374989"}
{"pmid": "4374988", "title": "Sexually-transmitted diseases in animals.", "content": "Sexually-transmitted diseases in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374988"}
{"pmid": "4374992", "title": "The effect of phenytoin on parathyroid extract and 25-hydroxycholecalciferol-induced bone resorption: adenosine 3, 5 cyclic monophosphate production.", "content": "The effect of phenytoin on parathyroid extract and 25-hydroxycholecalciferol-induced bone resorption: adenosine 3, 5 cyclic monophosphate production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374992"}
{"pmid": "4374993", "title": "Studies on dentinogenesis in the rat. The interaction between lead-pyrophosphate solutions and dentinal globules.", "content": "Studies on dentinogenesis in the rat. The interaction between lead-pyrophosphate solutions and dentinal globules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374993"}
{"pmid": "4374995", "title": "The conversion of cytochrome oxidase to an inactive form of the enzyme by water dialysis.", "content": "The conversion of cytochrome oxidase to an inactive form of the enzyme by water dialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374995"}
{"pmid": "4374994", "title": "Histochemical studies on alkaline phosphatases in mineralizing oral tissues in the mouse.", "content": "Histochemical studies on alkaline phosphatases in mineralizing oral tissues in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374994"}
{"pmid": "4374996", "title": "Phosphoribosyl pyrophosphate degradation in human tissues.", "content": "Phosphoribosyl pyrophosphate degradation in human tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374996"}
{"pmid": "4375000", "title": "The goldfish pituitary. I. Cytology.", "content": "The goldfish pituitary. I. Cytology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375000"}
{"pmid": "4375001", "title": "Cell autolysis and deletion in the planarian Polycelis tenuis Iijima.", "content": "Cell autolysis and deletion in the planarian Polycelis tenuis Iijima.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375001"}
{"pmid": "4375003", "title": "Fine structure and function of the alimentary epithelium in Artemia salina nauplii.", "content": "Fine structure and function of the alimentary epithelium in Artemia salina nauplii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375003"}
{"pmid": "4375002", "title": "The ACTH-interrenal axis in the freshwater stickleback, Gasterosteus aculeatus form leiurus.", "content": "The ACTH-interrenal axis in the freshwater stickleback, Gasterosteus aculeatus form leiurus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375002"}
{"pmid": "4375004", "title": "Ultracytochemistry of the lung of Polypterus ornatipinnis.", "content": "Ultracytochemistry of the lung of Polypterus ornatipinnis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375004"}
{"pmid": "4375005", "title": "Coronet cells in the neurohypophysis of Mugil capito Cuvier and Valenciennes (Teleostei) from a hypersaline lagoon.", "content": "Coronet cells in the neurohypophysis of Mugil capito Cuvier and Valenciennes (Teleostei) from a hypersaline lagoon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375005"}
{"pmid": "4375006", "title": "Ultrastructural study of arterio-venous anastomoses in gill filaments of Tilapia mossambica.", "content": "Ultrastructural study of arterio-venous anastomoses in gill filaments of Tilapia mossambica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375006"}
{"pmid": "4375007", "title": "Electron microscopic autoradiography of Ca-45 during dentinogenesis.", "content": "Electron microscopic autoradiography of Ca-45 during dentinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375007"}
{"pmid": "4375008", "title": "The hypothalamo-hypophysial system of hypophysectomized rats. I. Ultrastructure of nerve fibres in \"intact\" and dehydrated animals.", "content": "The hypothalamo-hypophysial system of hypophysectomized rats. I. Ultrastructure of nerve fibres in \"intact\" and dehydrated animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375008"}
{"pmid": "4374998", "title": "Comparison of postoperative irradiation alone and in combination with BCNU (NSC-409962) in the management of malignant gliomas.", "content": "Comparison of postoperative irradiation alone and in combination with BCNU (NSC-409962) in the management of malignant gliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374998"}
{"pmid": "4374999", "title": "Phosphoriboxyl transferase in colon tumor and normal mucosa as an aid in adjuvant chemotherapy with 5-fluorouracil (NSC-19893).", "content": "Phosphoriboxyl transferase in colon tumor and normal mucosa as an aid in adjuvant chemotherapy with 5-fluorouracil (NSC-19893).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374999"}
{"pmid": "4374997", "title": "Inhibition of Rauscher leukemia virus and avian myeloblastosis virus DNA polymerases by tilorone (NSC-143969) and its analogs.", "content": "Inhibition of Rauscher leukemia virus and avian myeloblastosis virus DNA polymerases by tilorone (NSC-143969) and its analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4374997"}
{"pmid": "4375014", "title": "The metabolism of low-density lipoprotein in a patient with familial hyperbetalipoproteinaemia.", "content": "The metabolism of low-density lipoprotein in a patient with familial hyperbetalipoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375014"}
{"pmid": "4375013", "title": "Changes in plasma lipoprotein lipids in hypercholesterolaemic patients treated with the bile acid-sequestering resin, colestipol.", "content": "Changes in plasma lipoprotein lipids in hypercholesterolaemic patients treated with the bile acid-sequestering resin, colestipol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375013"}
{"pmid": "4375015", "title": "A new approach to estrogen-free contraception based on progesterone receptor blockage by mid-cycle administration of ethyl norgestrienone (R 2323).", "content": "A new approach to estrogen-free contraception based on progesterone receptor blockage by mid-cycle administration of ethyl norgestrienone (R 2323).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375015"}
{"pmid": "4375016", "title": "Microbiological assay in quantitative histochemistry.", "content": "Microbiological assay in quantitative histochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375016"}
{"pmid": "4375017", "title": "SQ 65,396: a non-sedative anxiolytic?", "content": "SQ 65,396: a non-sedative anxiolytic?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375017"}
{"pmid": "4375018", "title": "Recent progress in studies of mouse type-C viruses.", "content": "Recent progress in studies of mouse type-C viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375018"}
{"pmid": "4375019", "title": "The biochemistry of icosahedral cytoplasmic deoxyviruses.", "content": "The biochemistry of icosahedral cytoplasmic deoxyviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375019"}
{"pmid": "4375026", "title": "Mode of existence of corticosterone in adrenal cells with reference to storage and secretion.", "content": "Mode of existence of corticosterone in adrenal cells with reference to storage and secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375026"}
{"pmid": "4375028", "title": "Phosphorylation of nuclear proteins fron bovine anterior pituitary gland induced by adenosine 3':5'-monophosphate.", "content": "Phosphorylation of nuclear proteins fron bovine anterior pituitary gland induced by adenosine 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375028"}
{"pmid": "4375027", "title": "Effect of ACTH and dexamethasone on the rate of protein and RNA degradation in rat adrenal glands.", "content": "Effect of ACTH and dexamethasone on the rate of protein and RNA degradation in rat adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375027"}
{"pmid": "4375029", "title": "The role of lysine and leucine binding on the catalytical and structural properties of aspartokinase III of Escherichia coli K 12.", "content": "The role of lysine and leucine binding on the catalytical and structural properties of aspartokinase III of Escherichia coli K 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375029"}
{"pmid": "4375030", "title": "The mechanism of inhibition of pig-plasma benzylamine oxidase by the copper-chelating reagent cuprizone.", "content": "The mechanism of inhibition of pig-plasma benzylamine oxidase by the copper-chelating reagent cuprizone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375030"}
{"pmid": "4375031", "title": "Effect of azide on some spectral and kinetic properties of pig-plasma benzylamine oxidase.", "content": "Effect of azide on some spectral and kinetic properties of pig-plasma benzylamine oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375031"}
{"pmid": "4375032", "title": "Synthesis of ATP from ADP and inorganic phosphate at the myosin-subfragment 1 active site.", "content": "Synthesis of ATP from ADP and inorganic phosphate at the myosin-subfragment 1 active site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375032"}
{"pmid": "4375033", "title": "A high-molecular-weight protein component required for natural messenger translation in ascites tumor cells.", "content": "A high-molecular-weight protein component required for natural messenger translation in ascites tumor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375033"}
{"pmid": "4375034", "title": "Chemical studies on Shigella sonnei lipid A.", "content": "Chemical studies on Shigella sonnei lipid A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375034"}
{"pmid": "4375035", "title": "Adenylate kinase of porcine heart.", "content": "Adenylate kinase of porcine heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375035"}
{"pmid": "4375037", "title": "Effect of imipramine on the behavior of rat-liver mitochondria during centrifugation in a sucrose gradient.", "content": "Effect of imipramine on the behavior of rat-liver mitochondria during centrifugation in a sucrose gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375037"}
{"pmid": "4375038", "title": "The covalently bound flavin of Chromatium cytochrome c552. 1. Evidence for cysteine thiohemiacetal at the 8 alpha position.", "content": "The covalently bound flavin of Chromatium cytochrome c552. 1. Evidence for cysteine thiohemiacetal at the 8 alpha position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375038"}
{"pmid": "4375039", "title": "Differences between the estradiol and testosterone receptors in rat uterus.", "content": "Differences between the estradiol and testosterone receptors in rat uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375039"}
{"pmid": "4375040", "title": "Synthesis and properties of N6, C-8 and C-2 spin-labelled derivatives of adenosine cyclic 3':5'-monophosphate.", "content": "Synthesis and properties of N6, C-8 and C-2 spin-labelled derivatives of adenosine cyclic 3':5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375040"}
{"pmid": "4375041", "title": "Studies on the metabolic effects induced in the rat by a high-fat diet. Control of glucose metabolism in adipose tissue of fed and fasted rats.", "content": "Studies on the metabolic effects induced in the rat by a high-fat diet. Control of glucose metabolism in adipose tissue of fed and fasted rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375041"}
{"pmid": "4375042", "title": "The interaction of apoprotein from porcine high-density lipoprotein with dimyristoyl phosphatidylcholine.", "content": "The interaction of apoprotein from porcine high-density lipoprotein with dimyristoyl phosphatidylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375042"}
{"pmid": "4375043", "title": "The interaction of apoprotein from porcine high-density lipoprotein with dimyristoyl phosphatidylcholine. Electron spin resonance and fluorescent probe. studies.", "content": "The interaction of apoprotein from porcine high-density lipoprotein with dimyristoyl phosphatidylcholine. Electron spin resonance and fluorescent probe. studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375043"}
{"pmid": "4375050", "title": "Proceedings: Multiple forms of adenosine 3':5'-cyclic monophosphate phosphodiesterase in bovine corpus luteum.", "content": "Proceedings: Multiple forms of adenosine 3':5'-cyclic monophosphate phosphodiesterase in bovine corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375050"}
{"pmid": "4375051", "title": "Proceedings: Partial purification and initial observations of molecular weights of luteal adenosine 3':5'-cyclic monophosphate-binding proteins.", "content": "Proceedings: Partial purification and initial observations of molecular weights of luteal adenosine 3':5'-cyclic monophosphate-binding proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375051"}
{"pmid": "4375052", "title": "Proceedings: Adenosine 3':5'-cyclic monophosphate-binding proteins in rat corpus luteum.", "content": "Proceedings: Adenosine 3':5'-cyclic monophosphate-binding proteins in rat corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375052"}
{"pmid": "4375053", "title": "Proceedings: Rat luteal adenosine 3':5'-cyclic monophosphate-dependent protein kinase.", "content": "Proceedings: Rat luteal adenosine 3':5'-cyclic monophosphate-dependent protein kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375053"}
{"pmid": "4375054", "title": "Proceedings: The effect of an ovulatory dose of human chorionic gonadotrophin on preovulatory adenosine 3':5'-cyclic monophosphate concentrations in rabbit ovarian tissue.", "content": "Proceedings: The effect of an ovulatory dose of human chorionic gonadotrophin on preovulatory adenosine 3':5'-cyclic monophosphate concentrations in rabbit ovarian tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375054"}
{"pmid": "4375055", "title": "Proceedings: Variation in urinary adenosine 3':5'-cyclic monophosphate contend during the human menstrual cycle.", "content": "Proceedings: Variation in urinary adenosine 3':5'-cyclic monophosphate contend during the human menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375055"}
{"pmid": "4375056", "title": "Proceedings: Control of glycerokinase activity by sex hormones.", "content": "Proceedings: Control of glycerokinase activity by sex hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375056"}
{"pmid": "4375057", "title": "Protein composition in developing human brain myelin.", "content": "Protein composition in developing human brain myelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375057"}
{"pmid": "4375058", "title": "Cysteamine-induced duodenal ulcers: a new model to test antiulcer agents.", "content": "Cysteamine-induced duodenal ulcers: a new model to test antiulcer agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375058"}
{"pmid": "4375059", "title": "Congenitally impaired hormone sensitivity of the adipose tissue of spontaneously diabetic mice, KK.  Validity of thrifty genotype in KK mice.", "content": "Congenitally impaired hormone sensitivity of the adipose tissue of spontaneously diabetic mice, KK.  Validity of thrifty genotype in KK mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375059"}
{"pmid": "4375061", "title": "The lipolytic system in adipose tissue of Toronto-KK and C57BL/KsJ diabetic mice. Adenylate cyclase, phosphodiesterase and protein kinase activities.", "content": "The lipolytic system in adipose tissue of Toronto-KK and C57BL/KsJ diabetic mice. Adenylate cyclase, phosphodiesterase and protein kinase activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375061"}
{"pmid": "4375060", "title": "Diabetes in the Toronto-KK hybrid mouse abnormalities in liver and pancreatic islets of Langerhans.", "content": "Diabetes in the Toronto-KK hybrid mouse abnormalities in liver and pancreatic islets of Langerhans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375060"}
{"pmid": "4375062", "title": "Lipolysis and adenosine 3'5'-cyclic monophosphate in adipose tissue of the New Zealand obese mouse; the activities of adipose tissue adenyl cyclase and phosphodiesterase.", "content": "Lipolysis and adenosine 3'5'-cyclic monophosphate in adipose tissue of the New Zealand obese mouse; the activities of adipose tissue adenyl cyclase and phosphodiesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375062"}
{"pmid": "4375064", "title": "Control of insulin secretion in the Egyptian sand rat ((Psammomys obesus).", "content": "Control of insulin secretion in the Egyptian sand rat ((Psammomys obesus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375064"}
{"pmid": "4375063", "title": "Evidence for decreased sensitivity to glucose of isolated islets from spiny mice. (Acomys cahirinus).", "content": "Evidence for decreased sensitivity to glucose of isolated islets from spiny mice. (Acomys cahirinus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375063"}
{"pmid": "4375069", "title": "Physiological studies of salmonella histidine operator-promoter mutants.", "content": "Physiological studies of salmonella histidine operator-promoter mutants. S. typhimurium hisO mutations are cis dominant and trans recessive and occur in a regulatory segment separate from but adjacent to the first structural gene of the histidine operon, hisG. Strains containing hisO mutations singly and in combination with other regulatory mutations were examined for their content of L-histidinol phosphate phosphatase when grown on limiting and on excess L-histidine. HisO mutations classed as \"constitutive\" (high enzyme levels) or as \"promoter-like\" (low enzyme levels) cause a variety of sub-phenotypes. A model is proposed that accounts for the phenotypes found as well as for the interspersion of constitutive and promoter-like mutations on the genetic map (Ely, Fankhauser and Hartman 1974). In this model we suggest that the his operator-promoter DNA is a functional unit that assumes alternate conformations including: (a) the classic linear duplex, active in transcription, and (b) a looped structure that is transcriptionally closed and susceptible to the binding of repressor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375069"}
{"pmid": "4375070", "title": "The clinical significance of immunological findings in Burkitt's lymphoma. (Epstein-Barr virus-associated antibodies/BCG treatment.", "content": "The clinical significance of immunological findings in Burkitt's lymphoma. (Epstein-Barr virus-associated antibodies/BCG treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375070"}
{"pmid": "4375071", "title": "Tumor virus RNAs tumor virus genes.", "content": "Tumor virus RNAs tumor virus genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375071"}
{"pmid": "4375073", "title": "Electron microscopic and cytochemic findings in Di-Guglielmo's syndrome and in other forms of leukemia.", "content": "Electron microscopic and cytochemic findings in Di-Guglielmo's syndrome and in other forms of leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375073"}
{"pmid": "4375072", "title": "DNA polymerases in lymphoid cells.", "content": "DNA polymerases in lymphoid cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375072"}
{"pmid": "4375076", "title": "Histochemical studies on the liver of white rats at various intervals after transection of the vagus nerves.", "content": "Histochemical studies on the liver of white rats at various intervals after transection of the vagus nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375076"}
{"pmid": "4375075", "title": "Histochemical studies on the gastric epithelium and glands in guinea pigs subjected to the action of a fungicide (Kaptan).", "content": "Histochemical studies on the gastric epithelium and glands in guinea pigs subjected to the action of a fungicide (Kaptan).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375075"}
{"pmid": "4375108", "title": "Abnormal duodenal loop in patients with sliding esophageal hiatal hernia -- studies on intragastric pressure and gastrocolic reflex.", "content": "Abnormal duodenal loop in patients with sliding esophageal hiatal hernia -- studies on intragastric pressure and gastrocolic reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375108"}
{"pmid": "4375116", "title": "Infrared spectra of DNA from normal & urethan-treated mice.", "content": "Infrared spectra of DNA from normal & urethan-treated mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375116"}
{"pmid": "4375115", "title": "Enzyme electrophoresis on cellulose acetate gel. II. Zymogram patterns in man-Chinese hamster somatic cell hybrids.", "content": "Enzyme electrophoresis on cellulose acetate gel. II. Zymogram patterns in man-Chinese hamster somatic cell hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375115"}
{"pmid": "4375117", "title": "Effect of exogenous 3',5'-cyclic adenosine monophosphate on the cell surface properties of the cellular slime mould, Dictyostelium discoideum.", "content": "Effect of exogenous 3',5'-cyclic adenosine monophosphate on the cell surface properties of the cellular slime mould, Dictyostelium discoideum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375117"}
{"pmid": "4375118", "title": "Purification and properties of a new extracellular collagenase from Aspergillus sclerotiorum.", "content": "Purification and properties of a new extracellular collagenase from Aspergillus sclerotiorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375118"}
{"pmid": "4375119", "title": "Permeation of nucleotidic coenzymes into liver cells.", "content": "Permeation of nucleotidic coenzymes into liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375119"}
{"pmid": "4375120", "title": "The purification and new properties of the neutral proteinase in human semen.", "content": "The purification and new properties of the neutral proteinase in human semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375120"}
{"pmid": "4375121", "title": "Endometrial biopsy using Gravlee Jet Washer and suction curette.", "content": "Endometrial biopsy using Gravlee Jet Washer and suction curette.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375121"}
{"pmid": "4375122", "title": "Effects of microquantities of 5 alpha-dihydrotestosterone on the epididymis and accessory glands of the castrated rhesus monkey, Macaca mulatta.", "content": "Effects of microquantities of 5 alpha-dihydrotestosterone on the epididymis and accessory glands of the castrated rhesus monkey, Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375122"}
{"pmid": "4375123", "title": "Effect of ageing on the volume, structure and total Leydig cell content of the human testis.", "content": "Effect of ageing on the volume, structure and total Leydig cell content of the human testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375123"}
{"pmid": "4375124", "title": "Sex ratio in extrauterine pregnancies.", "content": "Sex ratio in extrauterine pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375124"}
{"pmid": "4375125", "title": "Scanning electron microscopy of boar spermatozoa before and after frozen-thawed treatment.", "content": "Scanning electron microscopy of boar spermatozoa before and after frozen-thawed treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375125"}
{"pmid": "4375126", "title": "The influence of adoption on subsequent pregnancy in infertile marriage.", "content": "The influence of adoption on subsequent pregnancy in infertile marriage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375126"}
{"pmid": "4375127", "title": "The possible role of kinins in sperm motility.", "content": "The possible role of kinins in sperm motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375127"}
{"pmid": "4375128", "title": "Post tubal ligation menorrhagia and pelvic pain.", "content": "Post tubal ligation menorrhagia and pelvic pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375128"}
{"pmid": "4375129", "title": "Clinical evaluation of a new low dose progestagen-only contraceptive containing cingestol.", "content": "Clinical evaluation of a new low dose progestagen-only contraceptive containing cingestol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375129"}
{"pmid": "4375130", "title": "Survival of Entamoeba and related amoebae at low temperature-II. Viability of amoebae and cysts stored in liquid nitrogen.", "content": "Survival of Entamoeba and related amoebae at low temperature-II. Viability of amoebae and cysts stored in liquid nitrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375130"}
{"pmid": "4375131", "title": "Observation of surface active lysosomes and other organelles in monoxenically cultivated trophozoites of ent amoeba histolytica and Ent amoeba coli.", "content": "Observation of surface active lysosomes and other organelles in monoxenically cultivated trophozoites of ent amoeba histolytica and Ent amoeba coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375131"}
{"pmid": "4375132", "title": "Isolation of avian nephroblastoma virus from avian myeloblastosis virus by the infectious DNA technique.", "content": "Isolation of avian nephroblastoma virus from avian myeloblastosis virus by the infectious DNA technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375132"}
{"pmid": "4375133", "title": "Analysis of chromosomes of syrian hamster cells transformed with human cytomegalovirus.", "content": "Analysis of chromosomes of syrian hamster cells transformed with human cytomegalovirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375133"}
{"pmid": "4375134", "title": "A systematic approach to sleep disorders: review and treatment.", "content": "A systematic approach to sleep disorders: review and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375134"}
{"pmid": "4375141", "title": "Different patterns of chromosome exchange induced by methyl-metanesulphonate and mitomycin C in human cells.", "content": "Different patterns of chromosome exchange induced by methyl-metanesulphonate and mitomycin C in human cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375141"}
{"pmid": "4375142", "title": "Minor salivary glands of man: enzyme and mucosubstance histochemical studies.", "content": "Minor salivary glands of man: enzyme and mucosubstance histochemical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375142"}
{"pmid": "4375143", "title": "Salivary glands of the cat: a histochemical study.", "content": "Salivary glands of the cat: a histochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375143"}
{"pmid": "4375145", "title": "Adenylate cyclase in an estradiol sensitive tissue: a cytochemical study.", "content": "Adenylate cyclase in an estradiol sensitive tissue: a cytochemical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375145"}
{"pmid": "4375148", "title": "Fine structure of an edentate (Dasypus novemcinctus) male reproductive system: the epididymis.", "content": "Fine structure of an edentate (Dasypus novemcinctus) male reproductive system: the epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375148"}
{"pmid": "4375150", "title": "Proceedings: Small dense-cored vesicles in the cholinergic nerve terminals of the rat bladder.", "content": "Proceedings: Small dense-cored vesicles in the cholinergic nerve terminals of the rat bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375150"}
{"pmid": "4375149", "title": "Proceedings: Human mast cell degranulation and vacuolation.", "content": "Proceedings: Human mast cell degranulation and vacuolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375149"}
{"pmid": "4375151", "title": "Proceedings: Early Tasmanian morphology - new archaeological evidence.", "content": "Proceedings: Early Tasmanian morphology - new archaeological evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375151"}
{"pmid": "4375152", "title": "Trigeminal motor neuropathy.", "content": "Trigeminal motor neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375152"}
{"pmid": "4375153", "title": "Neurological episodes following epidemic conjunctivitis.", "content": "Neurological episodes following epidemic conjunctivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375153"}
{"pmid": "4375154", "title": "Inhibition of growth and DNA synthesis in cell cultures by cyclic AMP.", "content": "Inhibition of growth and DNA synthesis in cell cultures by cyclic AMP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375154"}
{"pmid": "4375155", "title": "Nucleolar development in the interphase of the cell cycle.", "content": "Nucleolar development in the interphase of the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375155"}
{"pmid": "4375156", "title": "Descriptive and quantitative study of ultrastructural changes in the apical meristem of mustard in transition to flowering. II. The cytoplasm, mitochondria and proplastids.", "content": "Descriptive and quantitative study of ultrastructural changes in the apical meristem of mustard in transition to flowering. II. The cytoplasm, mitochondria and proplastids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375156"}
{"pmid": "4375157", "title": "Cytokinesis in the heliozoan Actinophrys sol.", "content": "Cytokinesis in the heliozoan Actinophrys sol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375157"}
{"pmid": "4375158", "title": "The chloroplast nucleoid in Ochromonas danica. I. Three-dimensional morphology in light- and dark-grown cells.", "content": "The chloroplast nucleoid in Ochromonas danica. I. Three-dimensional morphology in light- and dark-grown cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375158"}
{"pmid": "4375159", "title": "The chloroplast nucleoid in Ochromonas danica. II. Evidence for an increase in plastid DNA during greening.", "content": "The chloroplast nucleoid in Ochromonas danica. II. Evidence for an increase in plastid DNA during greening.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375159"}
{"pmid": "4375160", "title": "Avian sarcoma virus transformed hamster cells made resistant to ethidium bromide.", "content": "Avian sarcoma virus transformed hamster cells made resistant to ethidium bromide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375160"}
{"pmid": "4375161", "title": "The subcellular distribution of prolyl hydroxylase determined immunohistochemically.", "content": "The subcellular distribution of prolyl hydroxylase determined immunohistochemically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375161"}
{"pmid": "4375162", "title": "Cytotoxic compounds. Part XX. Reactions of the methanesulphonates of 2-aryl-2-(arylthio)ethanols and of 1-aryl-2-(arylthio)ethanols with nucleophiles.", "content": "Cytotoxic compounds. Part XX. Reactions of the methanesulphonates of 2-aryl-2-(arylthio)ethanols and of 1-aryl-2-(arylthio)ethanols with nucleophiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375162"}
{"pmid": "4375169", "title": "Relation of enterotoxigenic Clostridium perfringens type A to food poisoning. I. Effect of heat activation on the germination, sporulation and enterotoxigenesis of c. perfringens.", "content": "Relation of enterotoxigenic Clostridium perfringens type A to food poisoning. I. Effect of heat activation on the germination, sporulation and enterotoxigenesis of c. perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375169"}
{"pmid": "4375170", "title": "Mutants of Aspergillus nidulans impaired in penicillin biosynthesis.", "content": "Mutants of Aspergillus nidulans impaired in penicillin biosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375170"}
{"pmid": "4375171", "title": "The effect of Rowson-Parr virus on the severity of malaria in mice.", "content": "The effect of Rowson-Parr virus on the severity of malaria in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375171"}
{"pmid": "4375172", "title": "Segmental reflex pathways in spinal shock and spinal spasticity in man.", "content": "Segmental reflex pathways in spinal shock and spinal spasticity in man. Activity in three segmental pathways was compared in normal subjects, patients with spinal shock, and patients with established spinal spasticity. The Achilles tendon reflex (ATR) was used to estimate transmission in the Ia monosynaptic pathway. Evidence is produced implying that vibration activates motoneurones principally through a polysynaptic pathway. The tonic vibration reflex (TVR) was used to estimate transmission in this Ia polysynaptic pathway. The percentage of the motoneurone pool (M-response) that could be activated by these pathways was used as a measure of transmission. The H reflex (vibration)/H reflex (control) ratio was used as an estimate of the degree of presynaptic inhibition of the Ia monosynaptic pathway. The findings led to the following conclusions. (1) In spinal shock presynaptic inhibition is greater than normal, transmission in the Ia monosynaptic pathway is reduced, and in the Ia polysynaptic pathway virtually abolished. (2) In established spasticity presynaptic inhibition is impaired, transmission in the Ia monosynaptic pathway is increased, but transmission in the Ia polysynaptic pathway never recovers. (3) The failure of presynaptic inhibition associated with spasticity is a gradual process. A hypothesis to explain these findings is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375172"}
{"pmid": "4375173", "title": "Regional cerebral blood flow and intraventricular pressure in acute head injuries.", "content": "Regional cerebral blood flow and intraventricular pressure in acute head injuries. Twelve patients who were comatose after head injuries were studied with serial determinations of regional cerebral blood flow, jugular PO(2) tension, and intraventricular pressure. These determinations began a few hours after the injury, and were followed throughout the clinical course. Diffuse derangement of cerebral vasomotor regulation is confirmed after severe head trauma, which may contribute to deterioration and poor prognosis, and which indicates a need for therapeutic maintenance of rich oxygenation, hyperventilation with moderate hypocapnia, and steady blood pressure. Continuous recording of IVP (eventually sensitized by fluid infusion or CO(2) inhalation tests) may give an early indication of the subsequent clinical state and may suggest the need to submit the patients to further investigative and therapeutic procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375173"}
{"pmid": "4375174", "title": "Ischaemic lateral popliteal nerve palsy due to ergot intoxication.", "content": "Ischaemic lateral popliteal nerve palsy due to ergot intoxication. A patient with ergot intoxication due to medication for migraine developed lateral popliteal nerve palsy. This is attributed to recurrent ischaemia caused by ergotamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375174"}
{"pmid": "4375175", "title": "A revised boron-neutron capture therapy for malignant brain tumours. I. Experience on terminally ill patients after Co-60 radiotherapy.", "content": "A revised boron-neutron capture therapy for malignant brain tumours. I. Experience on terminally ill patients after Co-60 radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375175"}
{"pmid": "4375176", "title": "Amyloid neuropathy: report of a case verified by autopsy.", "content": "Amyloid neuropathy: report of a case verified by autopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375176"}
{"pmid": "4375177", "title": "Anticonvulsant activity and selective inhibition of nicotinamide adenine dinucleotide-dependent oxidations by 1,3,5-trisubstituted pyrazolines.", "content": "Anticonvulsant activity and selective inhibition of nicotinamide adenine dinucleotide-dependent oxidations by 1,3,5-trisubstituted pyrazolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375177"}
{"pmid": "4375179", "title": "Verapamil blockade of slow Na+ and Ca++ responses in myocardial cells.", "content": "Verapamil blockade of slow Na+ and Ca++ responses in myocardial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375179"}
{"pmid": "4375178", "title": "Studies of fetal mouse hearts in organ culture: influence of prolonged exposure to triiodothyronine on cardiac responsiveness to isoproterenol, glucagon, theophylline, acetylcholine and dibutyryl cyclic 3',5'-adenosine monophosphate.", "content": "Studies of fetal mouse hearts in organ culture: influence of prolonged exposure to triiodothyronine on cardiac responsiveness to isoproterenol, glucagon, theophylline, acetylcholine and dibutyryl cyclic 3',5'-adenosine monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375178"}
{"pmid": "4375180", "title": "Comparative effects of tetracyclines on water flow across toad urinary bladders.", "content": "Comparative effects of tetracyclines on water flow across toad urinary bladders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375180"}
{"pmid": "4375181", "title": "Structure-activity relations for caffeine: a comparative study of the inotropic effects of the methylxanthines, imidazoles and related compounds on the frog's heart.", "content": "Structure-activity relations for caffeine: a comparative study of the inotropic effects of the methylxanthines, imidazoles and related compounds on the frog's heart. 1. The ability of several groups of compounds, related to caffeine, to induce contractures in isolated frog auricular trabeculae has been tested.2. Of the methylxanthines, theophylline, theobromine and paraxanthine are of similar potency to caffeine. This applies to contractures produced in either high-potassium or in sodium-free solution, and to the twitch responses in normal Ringer.3. Xanthines in which the 9-position nitrogen is combined and is, therefore, without an ethylene bond do not affect contraction.4. The hypothesis is put forward that a double-bonded nitrogen, in an imidazole ring, is required for activity of the methylxanthine. This hypothesis is supported by the ability of imidazole and several close derivatives (e.g. histamine), as well as imidazolines, to evoke contractures. As predicted by the hypothesis, imidazolidines and imidazolidones, in which all the nitrogen atoms have single bonds, fail to initiate tension development.5. The activity of histamine and histidine is only demonstrable at high pH ( bumpy equals, equals 9.0).6. Raising the pH in sodium-free solution induces a transient contracture.7. Several arguments suggest that cyclic AMP is probably not an intermediate in the response to the methylxanthines. The activity of cyclic AMP (and adenosine) in eliciting contractures is predicted by the hypothesis because they contain an imidazole moiety as part of their molecular structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375181"}
{"pmid": "4375183", "title": "The rate and depth of breathing in new-born infants in different sleep states.", "content": "The rate and depth of breathing in new-born infants in different sleep states. 1. Ventilation was recorded on ten male and ten female healthy full-term infants during the first week after delivery, using a trunk plethysmograph. Tidal volume (V(T)), respiration rate (f) and pulmonary ventilation (V) for each respiratory cycle were measured during periods of rapid eye movement sleep (REM) and during quiet sleep when eye movements were absent (NREM).2. It was found that mean instantaneous V and f were significantly higher in all infants during REM than during NREM sleep, while mean V(T) was either unchanged or showed a decrease. In addition, there was significantly greater variation in instantaneous V, V(T) and f during REM as compared with NREM sleep.3. Positive correlations were found in most infants in both sleep states between individual values of V(T) and the duration of the respiratory cycle (T).4. Periodic changes in T were found in all infants during both sleep states; these periodicities may reflect the behaviour of respiratory control mechanisms operating over a longer time span than the individual respiratory cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375183"}
{"pmid": "4375182", "title": "Effect of ouabain on renin secretion in anaesthetized dogs.", "content": "Effect of ouabain on renin secretion in anaesthetized dogs. 1. Pentobarbitone anaesthetized dogs were used to study the effects on renin secretion of ureteral occlusion and partial aortic clamping before and after intrarenal arterial administration of ouabain.2. Arterial plasma renin activity (A renin) and renal venous minus arterial plasma renin activity (RV-A renin) were both increased by either ureteral occlusion during mannitol diuresis or partial aortic clamping to reduce renal perfusion pressure. Intrarenal arterial ouabain administration blunted or abolished the effects of these manoeuvres on A and RV-A renins.3. The observations are not consistent with the hypothesis that renin secretion is uniquely controlled by afferent arteriolar transmural pressure. Both ureteral occlusion and aortic clamping reduce this pressure and increase renin secretion, yet evidence presented herein suggests that ouabain, which also decreases this pressure, decreases renin secretion.4. The observations are consistent with the hypothesis that renin secretion is controlled by tubular fluid flow and/or composition in the region of macula densa cells. Possibly changes in flow and/or composition are detected as changes in macula densa intracellular sodium concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375182"}
{"pmid": "4375184", "title": "The distribution, activity, and function of the cilia in the frog brain.", "content": "The distribution, activity, and function of the cilia in the frog brain. 1. The distribution, activity, and function of the cilia in the brain was studied using in vitro preparations of the frog choroid plexuses and ependyma.2. Scanning electron microscopy revealed that twenty to forty cilia, about 20 mum long, project from the cells of the choroidal epithelium and ependyma into the ventricular system of the brain.3. These cilia beat at a constant frequency which ranged from 5 to 20 c/s. Ciliary activity was enhanced by ATP, cyclic AMP, theophylline, and acetylcholine, and was depressed by DNP, IAA, Ni(2+), La(3+), and Co(2+).4. Ciliary motion produced a flow of c.s.f. over the surface of the cells lining the ventricles, and in the choroid plexus this flow reduced the effective thickness of the unstirred layer adjacent to the epithelium by about 100 mum.5. These results are discussed in relation to the factors that control the frequency of ciliary beating, and the role of the cilia in the circulation of the c.s.f.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375184"}
{"pmid": "4375185", "title": "Factors influencing plasma renin and angiotensin II in the conscious pregnant ewe and its foetus.", "content": "Factors influencing plasma renin and angiotensin II in the conscious pregnant ewe and its foetus. 1. Plasma renin (measured in the presence of additional substrate) was significantly higher (10.7 +/- 1.1 S.E. of mean ng/ml.hr) in foetal lambs of 111-144 days gestation age (full term 147 days) than in their mothers (1.5 +/- 0.2 ng/ml.hr S.E. of mean, P < 0.001) but plasma angiotensin II concentrations were in the same range (ewe 47.3 +/- 6.6 S.E. of mean, foetus 47.4 +/- 14.1 S.E. of mean pg/ml.). The endogenous velocity of renin production by foetal plasma was also greater than that of maternal plasma.2. Foetal plasma [Na(+)] (137 +/- 0.8 S.E. of mean m-equiv/l.), was lower than that in the ewe (142 +/- 1.5 m-equiv/l. S.E. of mean, P < 0.01).3. Foetal plasma renin in lambs of less than 120 days gestation was lower (9.2 +/- 2.7 S.E. of mean ng/ml.hr) than that in lambs of over 130 days gestation (12.6 +/- 2.6 ng/ml.hr S.E. of mean, P < 0.01). Foetal plasma [K(+)] (3.8 +/- 0.1 S.E. of mean m-equiv/l.) was also lower in lambs of less than 120 days gestation than in those over 130 days (4.1 +/- 0.1 S.E. of mean m-equiv/l., P < 0.001).4. When small volumes of blood (</= 3% of blood volume) were withdrawn from foetal lambs, plasma renin increased. The% increase of plasma renin in hypoxaemic foetal lambs was significantly less (P < 0.05) than in control lambs. At the end of 60 min hypoxaemia, arterial pressure and plasma [K(+)] were significantly higher in hypoxaemic than in control foetal lambs.5. During foetal hypoxaemia, plasma angiotensin II concentration increased concurrently with plasma renin.6. Bilateral nephrectomy was performed in two foetal lambs. Plasma renin fell to very low levels and angiotensin II became undetectable.7. Adrenaline ( approximately .0.42 mug/min.kg I.V.) infused into the foetus did not alter foetal plasma renin. When adrenaline was infused into the ewe ( approximately 0.26 mug/min.kg) maternal plasma renin increased. Maternal infusion of adrenaline raised foetal plasma renin significantly more (P < 0.05) than foetal infusion.8. It is concluded that the foetal kidney is the major source of foetal renin in the last quarter of gestation and that renin release is stimulated by very small reductions of blood volume. Hypoxaemia does not augment renin release and cannot be responsible for high levels of renin and angiotensin associated with vaginal delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375185"}
{"pmid": "4375192", "title": "[Sleep-wakefulness cycle in adult rats applied arsenic trioxide from birth to weaning (author's transl)].", "content": "[Sleep-wakefulness cycle in adult rats applied arsenic trioxide from birth to weaning (author's transl)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375192"}
{"pmid": "4375193", "title": "The advantages of HeLa cells for isolation of rhinoviruses.", "content": "The advantages of HeLa cells for isolation of rhinoviruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375193"}
{"pmid": "4375194", "title": "Reinvestigations of the relationship between sporulation, heat resistance and some biochemical properties in strains of Clostridium perfringens.", "content": "Reinvestigations of the relationship between sporulation, heat resistance and some biochemical properties in strains of Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375194"}
{"pmid": "4375195", "title": "Variation in polymyxin sensitivity among colonies in primary plate cultures of Vibrio eltor.", "content": "Variation in polymyxin sensitivity among colonies in primary plate cultures of Vibrio eltor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375195"}
{"pmid": "4375196", "title": "Prevalence in Italy of antibodies to a new human papovavirus (BK virus).", "content": "Prevalence in Italy of antibodies to a new human papovavirus (BK virus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375196"}
{"pmid": "4375197", "title": "Herpesvirus (strain 0430) lesions in Cercopithecus aethiops.", "content": "Herpesvirus (strain 0430) lesions in Cercopithecus aethiops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375197"}
{"pmid": "4375198", "title": "A procedure for the isolation of Herpesvirus saimiri lymphocyte-associated viruses and blood parasites from monkeys living in the wild.", "content": "A procedure for the isolation of Herpesvirus saimiri lymphocyte-associated viruses and blood parasites from monkeys living in the wild.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375198"}
{"pmid": "4375199", "title": "The half-of-the-sites reactivity of horse liver alcohol dehydrogenase in the presence of alcohol substrates.", "content": "The half-of-the-sites reactivity of horse liver alcohol dehydrogenase in the presence of alcohol substrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375199"}
{"pmid": "4375200", "title": "Action of Escherichia coli P1 restriction endonuclease on simian virus 40 DNA.", "content": "Action of Escherichia coli P1 restriction endonuclease on simian virus 40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375200"}
{"pmid": "4375201", "title": "Half-of-the-sites and all-of-the-sites reactivity in rabbit muscle glyceraldehyde 3-phosphate dehydrogenase.", "content": "Half-of-the-sites and all-of-the-sites reactivity in rabbit muscle glyceraldehyde 3-phosphate dehydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375201"}
{"pmid": "4375202", "title": "Nucleotide alterations in the bacteriophage T4 glutamine transfer RNA that affect ochre suppressor activity.", "content": "Nucleotide alterations in the bacteriophage T4 glutamine transfer RNA that affect ochre suppressor activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375202"}
{"pmid": "4375203", "title": "Letter to the editor: In vivo incorporation of cytosine arabinoside into simian virus 40 DNA.", "content": "Letter to the editor: In vivo incorporation of cytosine arabinoside into simian virus 40 DNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375203"}
{"pmid": "4375204", "title": "Assessment of steatorrhoea in malnourished children.", "content": "Assessment of steatorrhoea in malnourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375204"}
{"pmid": "4375224", "title": "Adrenergic receptors in rat liver. II. Effects of phenylephrine, isoproterenol and adrenergic blocking agents on gluconeogenesis in perfused liver.", "content": "Adrenergic receptors in rat liver. II. Effects of phenylephrine, isoproterenol and adrenergic blocking agents on gluconeogenesis in perfused liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375224"}
{"pmid": "4375225", "title": "Effects of cytochrome C on lipid and sugar metabolism in aged rats.", "content": "Effects of cytochrome C on lipid and sugar metabolism in aged rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375225"}
{"pmid": "4375226", "title": "Histopathological studies of the effects of cytochrome C on carbon tetrachloride-induced liver damage and on the livers of aged rats.", "content": "Histopathological studies of the effects of cytochrome C on carbon tetrachloride-induced liver damage and on the livers of aged rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375226"}
{"pmid": "4375229", "title": "Failure to induce neoplasma in CBA mice inoculated with highly attenuated Herpes simplex virus (SKa strain).", "content": "Failure to induce neoplasma in CBA mice inoculated with highly attenuated Herpes simplex virus (SKa strain).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375229"}
{"pmid": "4375230", "title": "Migration inhibition test in mice inoculated with Herpes simplex virus.", "content": "Migration inhibition test in mice inoculated with Herpes simplex virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375230"}
{"pmid": "4375231", "title": "Canine respiratory virus infections.", "content": "Canine respiratory virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375231"}
{"pmid": "4375232", "title": "Functional islet cell tumour in the dog.", "content": "Functional islet cell tumour in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375232"}
{"pmid": "4375233", "title": "Fluorescence and circular dichroism studies on human serum low density lipoprotein particles and lipid-depleted derivatives.", "content": "Fluorescence and circular dichroism studies on human serum low density lipoprotein particles and lipid-depleted derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375233"}
{"pmid": "4375235", "title": "Cyclic AMP: purification of protamine kinase.", "content": "Cyclic AMP: purification of protamine kinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375235"}
{"pmid": "4375236", "title": "Affinity chromatography of vertebrate collagenases.", "content": "Affinity chromatography of vertebrate collagenases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375236"}
{"pmid": "4375237", "title": "Affinity chromatography of urokinase.", "content": "Affinity chromatography of urokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375237"}
{"pmid": "4375238", "title": "Affinity chromatography of steroid-transforming enzymes.", "content": "Affinity chromatography of steroid-transforming enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375238"}
{"pmid": "4375239", "title": "Separation of isozymes.", "content": "Separation of isozymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375239"}
{"pmid": "4375240", "title": "Lactate dehydrogenase: specific ligand approach.", "content": "Lactate dehydrogenase: specific ligand approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375240"}
{"pmid": "4375241", "title": "Affinity chromatography of phosphodiesterase from snake venom.", "content": "Affinity chromatography of phosphodiesterase from snake venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375241"}
{"pmid": "4375242", "title": "Affinity chromatography of insulin receptors.", "content": "Affinity chromatography of insulin receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375242"}
{"pmid": "4375243", "title": "Affinity chromatography of estrogen receptors.", "content": "Affinity chromatography of estrogen receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375243"}
{"pmid": "4375245", "title": "Topics in the methodology of substitution reactions with agarose.", "content": "Topics in the methodology of substitution reactions with agarose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375245"}
{"pmid": "4375244", "title": "Affinity chromatography of thyrotropin receptors and antibody.", "content": "Affinity chromatography of thyrotropin receptors and antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375244"}
{"pmid": "4375251", "title": "Influence and control; insurance for nursing's future.", "content": "Influence and control; insurance for nursing's future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375251"}
{"pmid": "4375252", "title": "Nursing practice in a changing world.", "content": "Nursing practice in a changing world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375252"}
{"pmid": "4375253", "title": "External degree potential for Minnesota.", "content": "External degree potential for Minnesota.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375253"}
{"pmid": "4375255", "title": "Neonatal chemical sympathectomy: functional control of denervation of the vascular system and tissue noradrenaline level in the rat after 6-hydroxydopamine.", "content": "Neonatal chemical sympathectomy: functional control of denervation of the vascular system and tissue noradrenaline level in the rat after 6-hydroxydopamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375255"}
{"pmid": "4375256", "title": "Rat diaphragm cyclic nucleotide-phosphodiesterase: influence of drugs affecting skeletal muscle contractility.", "content": "Rat diaphragm cyclic nucleotide-phosphodiesterase: influence of drugs affecting skeletal muscle contractility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375256"}
{"pmid": "4375260", "title": "Pituitary adrenal function after small and large lesions in the lateral septal area in food-deprived rats.", "content": "Pituitary adrenal function after small and large lesions in the lateral septal area in food-deprived rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375260"}
{"pmid": "4375258", "title": "Effect of nomifensine on motor activity, dopamine turnover rate and cyclic 3',5;-adenosine monophosphate concentrations of rat striatum.", "content": "Effect of nomifensine on motor activity, dopamine turnover rate and cyclic 3',5;-adenosine monophosphate concentrations of rat striatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375258"}
{"pmid": "4375259", "title": "Demonstration of nuclear 3H-estradiol binding in hypothalamus and amygdala of female, androgenized-female, and male rats.", "content": "Demonstration of nuclear 3H-estradiol binding in hypothalamus and amygdala of female, androgenized-female, and male rats. The subcellular distribution of radioactivity in female, androgenized female, and male rats 1 hour after the iv administration of tritiated estradiol was examined.  High regional specificity among nucle ar fractions of brain areas was seen with the preoptic-anterior hypothal amic area (POA-AH), median eminence-basal hypothalamus (ME-BH), and amygdala having much higher nuclear binding than other brain  areas.  Nuc lear binding was receptor-mediated in POA-AH, ME-BH, amygdala, dorsal hypothalamus, and the prehypothalamic area in all groups, as demonstrate d by competetive inhibition with diethylstilbestrol (DES).  At this time period no differences between male and female rats in DES-blockable radioactivity levels of either nuclear or supernatant fractions in any brain area or pituitary were observed.  Androgenized females had lower DES-blockable, nuclear radioactivity levels in POA-AH, ME-BH, and uteri but the % of total tissue radioactivity in the nuclei did not differ between groups for any tissue.  These results demonstrate that males and females have similar estradiol uptake systems that are capable of high levels of nuclear binding in various brain areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375259"}
{"pmid": "4375257", "title": "Inhibition of fluid transport in the isolated gall bladder of the guinea pig by isoprenaline, theophylline and cyclic adenosine 3',5'-monophosphate.", "content": "Inhibition of fluid transport in the isolated gall bladder of the guinea pig by isoprenaline, theophylline and cyclic adenosine 3',5'-monophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375257"}
{"pmid": "4375261", "title": "Androgen effects on follicle-stimulating hormone (FSH) secretion in organ culture.", "content": "Androgen effects on follicle-stimulating hormone (FSH) secretion in organ culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/4375261"}