A method for determination of saturated phosphatidylcholine. Phosphatidylcholine preparations containing saturated and unsaturated molecular species were subjected to KMnO(4)-NaIO(4) oxidation in aqueous acetic acid, which left only disaturated species intact. After the oxidation, the remaining intact phosphatidylcholine was separated by thin-layer chromatography. The procedure could be used as a simple and rapid method for microdetermination of the saturated species in phosphatidylcholine preparations containing more than 0.1 micro mole of the saturated species. The contents of the saturated species in native phosphatidylcholines obtained from rat lung tissue and washings by this procedure were 35.7% and 58.3%, respectively.


A method for determination of the methylated constituents of transfer ribonucleic acid.


A method for quantitative determination of the abnormal lipoprotein of cholestasis, LP-X.


A new approach to the isolation of RNA-DNA hybrids and its application to the quantitative determination of labeled tumor virus RNA.


A new form of acute conjunctivitis epidemic in Taiwan. A simultaneous outbreak of adenovirus type II and "acute hemorrhagic conjunctivitis" virus infections.


A new form of beta-thalassemia trait.

A new form of beta-thalassemia trait.


A new method for radionuclide imaging of acute myocardial infarction in humans.


A rapid gas chromatographic-mass spectrometric method for prostaglandin analysis at picomole levels.


A seroepidemiological study of herpes simplex virus.


A potent interferon inducer derived from poly (7-deazainosinic acid).


A spin-label study of the photosynthetic bacterium, Rhodospirillum rubrum; Reduction and regeneration of nitroxide spin-labels.


A study of associated factors, including genital herpes, in Black women with cervical carcinoma in Johannesburg.


A study of auditory evoked responses during sleep.


A new hypothesis for the evolution of biological electron transport.


A study of pyruvate-induced inhibition in the dogfish lactate dehydrogenase system. Mechanistic comparison with the iodination of pyruvate.


A thermodynamic characterisation of the cytochromes of chromatophores from Rhodopseudomonas capsulata.


A study on cataplexy.

A study on cataplexy.


Abrogation of resistance to bone marrow grafts by silica particles. Prevention of the silica effect by the macrophage stabilizer poly-2-vinylpyridine N-oxide.


Acetolysis of dextran NRRL b1397. Preparation of trisaccharides containing (1 leads to 2)- and (1 leads to 6)-alpha-D-glucose linkages.


Achilles tendinitis and tenosynovitis. A diagnostic manifestation of familial type II hyperlipoproteinemia in children.


Acrodermatitis enteropathica associated with low density lipoproteins deficiency.


A study of methods of identification and estimation of Lp(a) lipoprotein and of its significance in health, hyperlipidaemia and atherosclerosis.


Action of alpha-1,6-glucan glucohydrolase on oligosaccharides derived from dextran.


Action of peptides and other algesic agents on paravascular pain receptors of the isolated perfused rabbit ear.


Activation of glycogenolysis in perfused rat livers by glucagon and metabolic inhibitors.


Activation of lordosis in ovariectomized guinea pigs by free and esterified forms of estrone, estradiol-17 beta and estriol.


Activation of pea leaf chloroplast sedoheptulose 1,7-diphosphate phosphatase by light and dithiothreitol.


Activation of simian virus 40 by transfer of isolated chromosomes from transformed cells.


Active site chloride binding in liver alcohol dehydrogenase.


Acute effects of ozone on cat lungs. II. Structural.


Active transport of iodide and other anions across the choroid plexus. 1. An in vitro preparation of the frog choroid plexus was used to study mechanisms of anion transport.2. It was observed that, in the absence of electrochemical potential gradients, there were net fluxes of I(-), SCN(-), TcO(4) (-), and Br(-) across the plexus, from the ventricular to the serosal surface. The net flux of I(-) reached a maximum at a concentration of 250 muM.3. On the basis of competition effects it was concluded that the affinity of the transport process for anions was: ClO(4) > ReO(4) approximately BF(4) > SCN approximately SeCN > I > NO(3) > Br > Cl.4. Ouabain, oligomycin, phloretin and 2,4-DNP inhibited the net transport of anions, but phlorrhizin, furosemide, 2,4,6-trinitro-m-cresolate, reducing agents, and antithyroid agents did not. Ouabain and phloretin were only effective on the ventricular side of the preparation.5. Anion transport required the presence of both Na and K. The requirement for Na was specific, but Rb, and to a lesser extent Cs, could substitute for K. Na in either the ventricular or the serosal fluids could partially stimulate anion transport, but K was only effective in the ventricular solution.6. TcO(4) (-), SCN(-) and I(-) were accumulated within the choroidal epithelium from the ventricular fluid, but not from the serosal fluid. Accumulation was inhibited by ouabain and ClO(4) (-).7. The unidirectional influx of I(-) across the apical cell membrane was about an order of magnitude greater than the flux across the epithelium. This flux was inhibited by ClO(4) (-), ouabain, and Na-free solutions.8. These experiments suggest the following mechanism for anion transport across the plexus: anions are actively transported into the epithelium, by a ouabain sensitive, Na/K dependent pump located in the brush border membrane. The anions are accumulated within the epithelium, and, finally, they pass into the serosal fluid down their electrochemical potential gradient. Relations between anion transport, Na/K transport, and Na/K ATPases are discussed.


Acute respiratory infections.

Acute respiratory infections.


Adenosine 3',5'-monophosphate in amniotic fluid from pregnancy complicated by hypertension.


Adenosine 3':5'-monophosphate and hormone interrelationships in the mammary gland of the rat during pregnancy and lactation.


Adenosine 3':5'-monophosphate dependent protein kinase isolated from rat Harderian gland.


Adenylate kinase from Pseudomonas denitrificans. I. Purification and antiserum inhibition.


Adenosine 3':5'-monophosphate-dependent protein kinase and the stimulation of ovarian nuclear ribonucleic acid polymerase activities.


Adrenal cells in tissue culture. The effect of papaverine and amytal on steroidogenesis, respiration and replication.


Adrenergic stimulation of phosphatidylinositol labelling in rat vas deferens.


Adrenoceptors and bronchial asthma.

Adrenoceptors and bronchial asthma.


Adrenocortical control of monoamine oxidase activity in the ground squirrel (Citellus citellus) during the winter.


Adrenocorticotrophic and growth hormone secretion. Studies during pneumoencephalography.


Affinity chromatography purification of diphtheria toxin.


Affinity of murine and human interferon for concanavalin A.


Agonist and antagonist relationships in 1- and 8-substituted analogs of angiotensin II.


Aetiology of hyperthyroidism. II.

Aetiology of hyperthyroidism. II.


Algesic actions of the polypeptides and other agents.


Allergenic glucans from dermatophytes. I. Isolation, purification, and biological properties.


An electron microscopy study of the effects on dibutyryl cyclic AMP on Chinese hamster ovary cells.


An epidemiologic study of breast cancer.


An epizootic of Sendai infection with mortality in a barrier-maintained mouse colony.


An extra species of lysine transfer ribonucleic acid in polyoma virus-transformed cells in tissue culture.


An estrogen binding protein in the renal cytosol of intact, castrated and estrogenized golden hamsters.


An intracellular alpha-D-glucan from Clostridium botulinum, type E.


An in-vitro bioassay for prolactin based on stimulation of casein synthesis by a dispersed cell preparation from mouse mammary gland.


An ultrastructural study of alkaline phosphatase activity in normal and neoplastic human salivary glands.


An isoenzyme of 5'-nucleotide phosphodiesterase and alpha-fetoprotein in human hepatic cancer patient sera.


An unusual variant of Klippel-Trenaunay-Weber syndrome. The association of soft tissue and bony overgrowth, varicose veins and port-wine nevus is known as Klippel-Trenaunay-Weber syndrome. An unusual case of a young woman with this syndrome is presented. In addition to the classic features she had face swelling, bilateral limb involvement and an infected cutaneous lymphangioma. No evidence of arteriovenous fistula was demonstrated. In contrast to an abnormal lymphatic system the deep veins of the limbs were normal. Unilateral lung lesions were demonstrated which have not been described previously in such cases.


Analysis of the RNA of defective VSV particles.


Angioleiomyoma of the skin.

Angioleiomyoma of the skin.


Androgen binding proteins in cock's tissues: properties of ear lobe protein and determination of binding sites in head appendages and other tissues.


Angiotensin infusion test in the diagnosis of renal hypertension.


Anterior interosseous nerve syndrome.

Anterior interosseous nerve syndrome.


Antibiotic neurotoxicity. Laboratory and clinical study.


Antibodies to Epstein-Barr virus-associated nuclear antigen in infectious mononucleosis.


Antibody to prolyl hydroxylase from rat skin and its cross-reactivity with enzyme from other species.


Application of measurement and control of dissolved oxygen pressure to vaccine production.


Antimicrobial therapy in children.

Antimicrobial therapy in children.


Application of serum alpha feto-protein assay in mass survey of primary carcinoma of liver. The Co-ordinating Group for the Research of Liver Cancer. People's Republic of China.


Aspects of continuous cultivation of spore-forming microbes from the group Bacillus thuringiensis.


Anti-C3d antiglobulin reagents. I. Characteristics of the anti-C3c and anti-C3d responses during hyperimmunization in rabbits.


Atherogenic and thrombogenic mosaic.

Atherogenic and thrombogenic mosaic.


Atherosclerosis as a pediatric problem.

Atherosclerosis as a pediatric problem.


Attitudes and behaviors of acute and chronic schizophrenic patients regarding ambulatory treatment.


Attempts to demonstrate the interferon defense mechanism in cultured mosquito cells.


Audiologic evaluation in cochlear and eighth nerve disorders.


Autonomous derivatives of estrogen-induced renal carcinomas and spontaneous renal tumors in the Syrian hamster.


Avian myeloblastosis virus DNA polymerase: initiation of DNA synthesis and an associated ribonuclease.


Basic rest-activity cycle in the perception of the spiral after-effect; a sensitive detector of a basic biological rhythm.


Baroreceptor activity and responsiveness to angiotensin in patients with chronic renal failure.


ATP-dependent calcium uptake by microsomal fractions of pig coronary artery and its dependence on bradykinin and angiotensin II.


Bentonite flocculation test for amoebiasis.


Biliary excretion in vivo of bile acids synthesized by hepatomas.


Atherosclerosis in the rhesus monkey fed three food fats.


Binding of spin-labeled local anesthetics to phosphatidylcholine and phosphatidylserine liposomes.


Biliary infections and the chouce of antibiotics.


Biochemical and biophysical studies on cytochrome c oxidase. XVIII. Potentiometric titrations of cytochrome c oxidase followed by circular dichroism.


Binding of steroids to progesterone receptor proteins in chick oviduct and human uterus.


Biochemical neuroendocrinology. I. Biosynthesis of thyrotropin releasing hormone (TRH) by organ cultures of mammalian hypothalamus.


Biochemistry and psychiatry with special reference to psychopharmacology.


Biogenic amine-containing neurons: biochemical mechanisms of synaptic transmission.


Biologic and immunologic comparison of two HSV-2 variants: one an isolate from cervical tumor cells.


Biosynthesis of 1-alkyl-sn-glycero-3-phosphate via adenosine triphosphate:1-alkyl-sn-glycerol phosphotransferase.


Biosynthesis of cholinesterase in rabbit bone marrow cells in culture.


Biosynthesis of glycolipids in virus-transformed cells.


Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 5. Bis-basic ethers of anthraquinone and bisalkamine esters of anthraquinonedicarboxylic acids.


Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 1,2 6. Bis-basic-substituted fluoranthenes.


Blastocystis hominis: axenic cultivation.


BGM, a continuous cell line more sensitive than primary rhesus and African green kidney cells for the recovery of viruses from water.


Calciferol and its relatives. XVII. Ring-A components for synthetic work on vitamin D3 and on model compounds.


Calcitonin secretion in vitro. I. Preparation of monolayer C-cell cultures.


Calcium homeostasis and the patogenesis and management of hypercalcemic disorders.


Calibration of a cascade centripeter dust sampler.


Calculated equilibria of phosphocreatine and adenosine phosphates during utilization of high energy phosphate by muscle.


Carbon-13 magnetic resonance assignments of the repeat peptides of elastin and solvent delineation of carbonyls.


Carbon-13 spin-lattice relaxation studies of intramolecular motion in lysine and a series of oligolysines.


Carcinoid tumours and cylindromas of the tracheobronchial tree.


Carcinoma of Skene's gland associated with urethral diverticulum: a case report.


Carcinoma of the breast in American Negro men.


Cataracts induced by surface active agents.


Cell cycle dependent transcription of SV40 DNA in SV40-transformed cells.


Cell fusion, using Sendai virus, to effect inter-species transfer of a cell-associated parasite (Theileria parva).


Cell surface modifications in virus-transformed cells--glycolipid changes in the NIL2 hamster cells.


Central and reflex regulation of sympathetic vasoconstrictor activity to limb muscles during desynchronized sleep in the cat.


Cellular immunity to herpes simplex virus mediated by interferon. Rabbit kidney cell monolayers infected with herpes simplex virus (HSV) were incubated with leukocytes from rabbits immunized with complete Freund's adjuvant. When the leukocytes were exposed to tuberculin purified protein derivative (PPD), viral replication and plaque formation were markedly inhibited. Similarly, when leukocytes from animals immunized with HSV were exposed to UV-inactivated HSV, viral replication was markedly inhibited. Exposure of leukocytes from unimmunized animals or animals immunized with incomplete Freund's adjuvant to UV-inactivated virus or PPD produced relatively little inhibition of viral replication. Examination of supernatant fluids from stimulated cultures revealed a soluble mediator that had the properties of interferon. Interferon production was detected within several hours after exposure of sensitized leukocytes to antigen. Supernatant fluids from as few as one sensitized leukocyte per 200 rabbit kidney cells inhibited HSV replication by over 90%. These findings support the concept that the cellular immune response to HSV consists of two phases: an immunologically specific antigen recognition phase, and a nonspecific effector phase that stops HSV spread by generating interferon.


Cerebral metastatic disease in childhood.


Cerebrospinal fluid concentration of cyclic adenosine-3',5'-monophosphate and pneumoencephalography.


Certain biochemical and ultrastructural features of the ventricular myocardium following cardiac denervation.


Change in the pituitary-adrenal function of silver foxes during selection according to behavior.


Changes in conformation of stereocilia in hair cells of the rat spiral organ of Corti after 6-hydroxydopamine as revealed by scanning electron microscopy.


Changes in chromatin proteins during liver regeneration.


Changes in the properties of the resident L virus in somatic cell hybrid lines.


Characteristics of sodium flux from serosa to mucosa in rabbit ileum. Sodium flux from serosa to mucosa, J(sm) (Na) in rabbit ileum in vitro has been studied as a function of applied electrical potential at equal sodium concentrations in the bathing solutions. The results indicate that J(sm) (Na) involves two pathways, a diffusional flux through a paracellular shunt pathway and a flux that is independent of applied potential and presumably involves a transcellular pathway. The latter pathway comprises approximately 25 % of J(sm) (Na) in Ringer's solution containing 10 mM glucose and 25 mM bicarbonate. It is stimulated significantly by theophylline unaffected by removal of glucose or addition of ouabain but is reduced to negligible values by anoxia, dinitrophenol, and replacement of all chloride and bicarbonate by isethionate. Thus this component of J(sm) (Na) has a number of characteristics consistent with involvement in a specific secretory process mediating an electrically neutral secretory transport of sodium plus anion from serosa to mucosa. In addition to stimulating this process, theophylline significantly reduced the permeability of the paracellular shunt pathway to sodium.


Characteristics of the cyclic 3',5'-AMP formation in isolated ovarian follicles from PMSG-treated immature rats after stimulation in vitro with gonadotrophins and prostaglandins.


Characterization and properties of progesterone-binding components in human endometrium.


Characterization of a hormone receptor defect in the androgen-insensitivity mutant.


Characterization of a normal, tissular antigen extracted from human colonic tumors.


Characterization of defective interfering viral particles present in a population of pseudorabies virions.


Characterization of multiplication of embryo-adapted avian encephalomyelitis virus in chick embryo brain cell cultures.


Characterization of the active site structures of arginine kinase-substrate complexes. Water proton magnetic relaxation rates and electron paramagnetic resonance spectra of manganous-enzyme complexes with substrates and of a transition state analog.


Characterization of the plasma lipoproteins of the genetically obese hyperlipoproteinemic Zucker fatty rat. The plasma lipoproteins of the Zucker fatty rat were characterized with respect to lipid and apoprotein composition, and results were compared with those obtained from lean controls. Information on apoproteins was obtained from gel filtration experiments and electrophoresis on polyacrylamide gels. Very low density lipoproteins (VLDL) were increased several-fold in fatties, and 78% of their mass was triglycerides compared with 60% in the controls. Low density (LDL) and high density (HDL) lipoproteins were increased by a factor of 2, although their compositions were similar to those of the controls. Levels of apoVLDL, apoLDL, and apoHDL were five, two and two times higher, respectively, in the fatties, and the two most rapidly moving subunit peptides on polyacrylamide gels were disproportionately elevated in the apoproteins. The slower of these two bands was present in relatively greater amounts than the faster one in fatties. If the slower peptide is an activator of lipoprotein lipase, analogous to the comparable subunit peptides of human apolipoproteins, plasmas of fatties could contain up to 10 times more lipase activator activity than control plasma. This finding, and the fact that adipose tissue lipoprotein lipase activity of fatties was about 150% of controls, suggests that fatties have increased capacities for VLDL catabolism. We have previously shown that hepatic VLDL secretory rates are higher than normal in these animals. The increased capacity for catabolism may be a response to the altered secretory rates.


Characterization of the rat apolipoproteins. I. The low molecular weight proteins of rat plasma high density lipoproteins.


Characterization of vesicular stomatitis virus nucleocapsids. I. Complementary 40 S RNA molecules in nucleocapsids.


Chemical and physiological approaches to neuroendocrine mechanisms: attempts at integration.


Chemical constituents of the digestive gland of the sea hare Aplysia californica. I. Importance of diet.


Chemical evolution. XXII. The hydantoins released on hydrolysis of HCN oligomers.


Chemistry of the hypothalamic releasing factors--studies on structure-function relationships.


Chemistry and biological activity of vitamin D, its metabolites and analogs.


Cholera enterotoxin stimulation of cAMP in cultured adrenal tumor cells.


Cholesterol metabolism in the Ehrlich ascites tumor.


Chromatin interaction with oestradiol-receptor protein complex.


Chromophobe adenoma masquerading as corticosteroid-responsive optic neuritis.


Clearing factor lipase and its role in the regulation of triglyceride utilization. Studies on the enzyme in adipose tissue.


Chlorophyll a and cytochrome c at a heptane-water interface.


Clofibrate reversal of platelet hypersensitivity in hyperbetalipoproteinemia.


Closed circular DNAs with tandem repeats of a sequence from polyoma virus.


Clostridial myonecrosis of the abdominal wall. Management after extensive resection.


Clostridium perfringens type C in hemorrhagic enterotoxemia of neonatal calves in Alberta.


Clostridium perfringens type D epsilon prototoxin. Some chemical, immunological and biological properties of a highly purified prototoxin.


Collagen synthesis by lathyrogen-treated 3T6 fibroblasts.


Collagen degradation in cultured keloid and hypertrophic scar tissue.


Collagenase induced changes in the circular dichroism spectrum of collagen.


Color-enhanced chest roentgenography: a feasibility report.


Committee on Environmental Hazards. Noise pollution: neonatal aspects.


Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in rats.


Comparative sensitivity and resistance of some strains of Pseudomonas aeruginosa and Pseudomonas stutzeri to antibacterial agents. A comparison has been made of the sensitivities to various antibiotic and non-antibiotic substances of some strains of Pseudomonas aeruginosa and P. stutzeri, the latter including strains isolated from eye and other cosmetic products and from other sources. Whereas P. aeruginosa strains showed a high resistance to cetrimide and to benzalkonium chloride, the P. stutzeri strains were generally more sensitive to these and to chlorhexidine. The P. stutzeri strains were also more sensitive to the various antibiotics tested. The loss of the ability to transfer an R factor by two strains of P. aeruginosa caused no significant change in their drug sensitivity pattern.


Comparison of effects of locally infused angiotensin I and II on hand veins and forearm arteries in man: evidence for converting enzyme activity in limb vessels.


Comparison of glucocorticoid cytoplasmic receptors from liver, Zajdela hepatoma and HTC cells.


Comparisons between induced by water deprivation or chemical stimulation.


Computerized tomography of the brain.

Computerized tomography of the brain.


Competitive binding assay for estradiol receptor using immobilized antibody.


Conditions influencing inhibitors of the colony-stimulating factor (CSF).


Conductometric evaluation of interactions of electrolytes with D-glucitol, D-glucose, glycerol, D-mannitol, and sucrose.


Congenital goiter due to maternal ingestion of iodide.


Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas. Three exceptional cell lines have been tested for the presence of the Epstein-Barr virus genome by nucleic acid hybridization (complementary RNA.DNA) and Epstein-Barr virus-determined nuclear antigen tests. Two lines were derived from Swedish lymphoma cases and one from an African Burkitt-like lymphoma biopsy that was negative for Epstein-Barr virus DNA and the virus-determined nuclear antigen. All three lines apparently lacked the viral genome. Two of the three lines clearly had characteristics of B-cells (bone-marrow-derived).


Cooperative interactions between native and modified subunits of rabbit liver fructose 1,6-bisphosphatase.


Correlation of (Na+--K+)-ATPase activity with growth of normal and transformed cells.


Control of uracil transport by cyclic AMP in E. coli.


Correlation of pretreatment serum nonprotein-bound cortisol and total 17-hydroxycorticosteroid values with survival in patients with prostatic cancer.


Corticosteroid therapy. Updating of principles.


Current problems in myocardial metabolism.


Comparative study of several hypolipidemic agents related to clofibrate.


Cushing's disease. Treatment by pituitary implantation of radioactive gold or yttrium seeds.


Cyclic changes in oviductal morphology and residual cytoplasmic estradiol binding capacity induced by sequential estradiol--progesterone treatment of spayed Rhesus monkeys.


Cyclic guanosine monophosphate: elevation in degenerating photoreceptor cells of the C3H mouse retina. As a result of an early deficiency in cyclic nucleotide phosphodiesterase activity, guanosine 3',5'-monophosphate accumulates in retinal photoreceptor cells before they begin to degenerate. It is suggested that degeneration of the photoreceptor cells is related to an imbalance in their metabolism or function which is caused by the elevated levels of cyclic guanosine monophosphate.


Cyclic AMP as a cell surface activating agent in Dictyostelium discoideum.


Cyclic AMP regulates phosphorylation of three protein components of rat cerebral cortex membranes for thirty minutes.


Cytidine 3',5'-monophosphate (cyclic CMP). II. Initiation of leukemia L-1210 cell growth in vitro.


Cytogenetic study of primary tumors of chemical and viral origin in the golden hamster. Communication I. Karyotypic characteristics of tumors induced by the Rous sarcoma virus and by 7,12-dimethylbenzanthracene.


Cytosol androgen receptor from kidney of normal and testicular feminized (Tfm) mice.


Cytomegalovirus: Clinical virological correlations in renal transplant recipients. One-hundred thirty-two renal transplant recipients were systematically screened for viral infections and the findings correlated with the clinical course. One-hundred ten patients showed evidence of infection with herpesviruses and 89 patients showed laboratory evidence of infection with cytomegalovirus (CMV) uncomplicated by bacterial infections or technical complications. Patients without viral infections were usually asymptomatic. After recovery and development of anti-viral antibodies, most patients were asymptomatic despite the persistence of viral excretion in the urine. In contrast, the onset of viral infections were almost always accompanied by a significant clinical illness characterized by fever, leukopenia, and renal malfunction. Of 89 patients with cytomegalovirus infections, 83 survived at least three months. In these patients, the fever appeared to be self-limited and resolution of the fever was accompanied by increases in anti-CMV antibody. Renal biopsies demonstrated typical rejection reactions in all the biopsied patients and renal malfunction usually responded to anti-rejection treatment. Six of the 89 patients with CMV infections died within a month of viral isolation. These patients could be distinguished from those who recovered by a decreased or absent antibody response to the virus, suppressed lymphocyte responses to mitogen in autochthonous blood, and absent histologic evidence of rejection in the renal allografts. Thus, two paradoxical responses to CMV infections are seen in transplant patients: In the relatively immunocompetent patient, the infection is associated with renal allograft rejection, a prompt antibody response to the virus, and recovery. The severely immunosuppressed patient cannot make an antibody response, does not exhibit allograft rejection as a cause of renal malfunction, he may be further immunosuppressed by the viral infection, and is susceptible to sequential opportunistic infections leading to death.


Daily changes in concentration of pancreatic and serum insulin and of blood glucose during 5 days of treatment of rats with growth hormone, ACTH, cortisol, dexamethasone, and tolbutamide alone and in combinations.


Daily rhythms of steroid and associated pituitary hormones in man and their relationship to sleep.


Day care for cancer patients.

Day care for cancer patients.


Degradation of O-phosphohydroxylysine in rat liver. Purification and properties of 2-aminoadipic semialdehyde dehydrogenase.


Demonstration of two immunologically distinct xenotropic type C RNA viruses of mouse cells.


Deoxycholate-mediated cleavage of the protein of Sendai virus nucleocapsid derived from infected cells.


Detection of tricuspid valve vegetations by echocardiography.


Depression of viral interferon induction in cell monolayers by coal dust.


Determinants and modification of adrenergic and vascular resistance in the kidney.


Determination of leptophos, leptophos oxon, and a possible phenolic photoconversion metabolite in rapeseed grain.


Development of hCG sensitivity in the testis of the immature rat.


Dialysis schedule and peripheral neuropathy.


Diazoxide, encorton and streptozotocin in the treatment of malignant betacytoma.


Dibutyryl cyclic AMP and cytotoxic lymphocytes in Hashimoto's thyroiditis.


Dietary modulation of beta cell adenylate cyclase activity.


Depression in infant monkeys: physiological correlates.


Differences between liver and hepatoma cells in their complements of adenosine 3':5'-monophosphate-binding proteins and protein kinases.


Differences between the integration of avian myeloblastosis virus DNA in leukemic cells and of endogenous viral DNA in normal chicken cells. The nature of integrated viral DNA in normal and leukemic chicken cells has been studied by sequential nucleic acid hybridization procedures that localize the viral specific DNA in cellular DNA regions differing in reiteration frequency. First, DNA.DNA reassociation was employed to fractionate cellular DNA sequences according to their reiteration frequencies. Next, the DNA in each fraction was denatured, immobilized on nitrocellulose filters, and then hybridized with viral [(3)H]RNA. In normal cells, endogenous viral DNA appears to be associated with cell sequences reiterated 1200 times, and each integration unit appears to have a maximal size approximately equivalent to the 35S RNA subunit of the virion. In infected cells, additional viral sequences are found which reassociate as if they integrated adjacent to unique cellular DNA, or in tandem with endogenous viral DNA.


Different sensitivity of nuclear and microsomal NADH-cytochrome c reductase activities to thenoyltrifluoroacetone.


Different effects of hormonal peptides and cyclic adenosine 3',5'-monophosphate on colonic transport in vitro.


Diffusion and convection in normal and neoplastic tissues.


Differential effects of an angiotensin II analogue on pressor and adrenal receptors in the rabbit.


Direct involvement of vitamin D in the regulation of 25-hydroxycholecalciferol metabolism.


Discharge planning: tentative program improves utilization.


Dilution kinetic studies of yeast populations: in vivo aggregation of galactose utilizing enzymes and positive regulator molecules. By use of a selective medium containing ethidium bromide, population analyses of yeast galactose long-term adaptation mutants (gal3) in the process of deadaptation in the absence of galactose have been performed. The analysis of diploid strains homozygous for the gal3 locus but heterozygous for different combinations of the other mutant galactose loci, which thus have reduced amounts of the gene products of those loci, have demonstrated that, in addition to the two permease units determined in a previous study, a cell requires one complex of the Leloir pathway enzymes and two complexes specified by the Gal4 locus to be readily induced. From the consideration of these complexes as being aggregated molecules which are diluted out as units (i.e., if such a molecule were a dimer, it would not dissociate into monomers) during cell growth, the in vivo aggregation of these enzymes and the Gal4 gene product could be studied. The data indicate that the function of the Gal4 gene product is to activate a Leloir enzyme complex. It is postulated that the gal3 phenotype is the result of such strains' inability to actively synthesize an endogenous co-inducer which allows wild-type cells to be readily induced upon exposure to galactose.


Dispersion and isolation of beating cells from adult rat heart.


Distinct molecular species of interferons.


Distribution patterns of hepatitis B antigen in the liver. Immunofluorescence studies.


Distrubances in tryptophan metabolism after a single dose of aflatoxin B1 and chronic intoxication with carbon tetrachloride.


Dominant lethal mutations induced in mice by orally administered ethyl methanesulfonate.


Dosimetry of the SIN biomedical pion beam with tissue-equivalent ionization chambers.


Dopaminergic inhibition of striatal cholinergic neurons: synergistic blocking action of gamma-butyrolactone and neuroleptic drugs.


Dosimetry studies on the ethylation of mouse sperm DNA after in vivo exposure to (3H)ethyl metanesulfonate.


DNA strand breakage caused by dichlorvos, methyl methanesulphonate and iodoacetamide in Escherichia coli and cultured Chinese hamster cells.


Dynamics of functional and ultrastructural changes in the liver cells during the development of allyl alcohol necrosis.


Early and late averaged electroencephalic responses at low sensation levels.


DNA strand scission by the antitumor protein neocarzinostatin.


Early and late viral-specific polyribosomal RNA in herpes virus-1 and -2-infected rabbit kidney cells.


Early components of the averaged electroencephalic response to monaural and binaural stimulation.


Early diagnosis of carcinoma of the bronchi with special reference to catheter biopsy.


Early tendon transfer in upper extremity peripheral nerve injury.


Editorial: Acute hemorrhagic conjunctivitis.


Editorial: Hepatitis and herpesvirus.

Editorial: Hepatitis and herpesvirus.


Editorial: Neuroblastoma: possible viral aetiology?


Editorial: Vaccination against whooping cough.


Editorial: The national Wilms tumor study. A progress report.


Effect of "Aquasol A", vitamin A, and "Tween 80" on vesicular stomatitis virus plaque formation and on interferon action.


Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin.


Effect of cytochalasin B on hexose transport and glucose metabolism in pancreatic islets.


Effect of energy-rich compounds on release of intracellular enzymes from human leukocytes and rat lymphocytes.


Effect of glucagon, dibutyryl adenosine 3',5'-cyclic monophosphate and phosphodiesterase inhibitors on rat liver phosphorylase activity and adenosine 3',5'-cyclic monophosphate levels.


Effect of flurazepam on sleep in the laboratory.


Effect of morphine on serotonin release from myenteric plexus of the guinea pig.


Effect of plasma protein concentration on glomerular and tubular function.


Effect of prostaglandins on the velocity of the reaction between human renin and homologous renin substrate.


Effect of subacute administration of human growth hormone on various serum lipid and hormone levels of hypercholesterolemic and normocholesterolemic subjects.


Effect of testes removal and androgen replacement therapy on enzyme levels in hypothalamus and pituitary of frog (Rana esculenta).


Effect of tissue injury on tumorigenesis induced by murine sarcoma virus (Harvey).


Effect of 1,10-phenanthroline and desferrioxamine in vivo on prolyl hydroxylase and hydroxylation of collagen in various tissues of rats.


Effect of IUD on uterine cyclic AMP and the activities of adenyl cyclase and phosphodiesterase during the oestrous cycle and early pregnancy in rats.


Effects of acetylimidazole on the hydrolysis of fructose diphosphate and p-nitrophenyl phosphate by liver fructose diphosphatase.


Effects of dimethylsulfoxide on the E. coli gal operon and on bacteriophage lambda in vivo.


Effects of drugs on the metabolism of bile acids.


Effects of growth phase and repair capacity on rejoining of ethyl methanesulfonate-induced DNA breaks in Escherichia coli.


Effects of factors influencing the activity of the reticuloendothelial system on the half-life of labelled beta-lipoproteins. Preliminary report.


Effects of pokeweed mitogen, cholera toxin and prostaglandin E1 on immunoglobulin production and cyclic AMP levels in tonsillar lymphocytes.


Effects of pituitary hormones and corticosterone on lipolysis in hypophysectomized rats.


Effects of prostaglandin E1 and isoproterenol on cyclic AMP content of human fibroblasts modified by time and cell density in subculture.


Effect of imipramine on adrenergic responses.


Effects of prostaglandins, cyclic AMP, seminal plasma, indomethacin, and other factors on oviposition in the Japanese quail, Coturnix coturnix japonica.


Effects of tetrahydrocannabinols on cyclic AMP levels in rat brain areas.


Effects of the 3',5'-cyclic phosphates of 2-methylthioadenosine, 2-chloroadenosine and adenosine on platelet aggregation.


Effect of propranolol on pituitary adrenal axis.


Elastosis in tubular carcinoma of the breast.


Effects of vitamin D3 on duodenal absorptive cells of chicks. An electron microscopic study.


Electromyography and nerve conduction measurements.


Electron microscopy of the pulmonary alveolar cells (granular pneumocytes) of normal and vagotomized amphibian (Bufo icterus icterus).


Effects of the combination of nicotinic acid and propranolol in very low doses on blood lipids in man.


Electron paramagnetic resonance of single crystal 15N-nitrosyl-57Fe-myoglobin.


Electron paramagnetic resonance studies of the structure and metal ion exchange kinetics of vanadyl(IV) bovine carbonic anhydrase.


Electrophoretic characterization of shuttling and nonshuttling small nuclear RNAs.


Elevation of renal cyclic GMP concentrations and plasma lysosomal enzyme activity following cobalt treatment in rats.


Elucidation of the exact sites of cleavage of tropocollagen by rheumatoid synovial collagenase: correlation of cleavage sites with fibril structure.


Embryonic differentiation in the nucleoside triphosphatase activities of myosin from the fast, slow and cardiac muscles of chick.


Electron microscope studies of the antileprosy drug B663 (clofazimine; Lamprenel).


Endocrine disorders as a contributory factor to neoplasia in SJL-J mice.


Endocrine evaluation in thalassemia major.


Endocrine function in thalassemia major.


Enhancement of Simian virus 40-induced transformation of Chinese hamster embryo cells by 4-nitroquinoline 1-oxide.


Envelope proteins of vesicular stomatitis virions: accessibility to iodination.


Enzymatic activation of Clostridium perfringens epsilon prototoxin and some biological properties of activated toxin.


Epidemiology as a field of practice.

Epidemiology as a field of practice.


Episodic secretion of luteinizing hormone-releasing factor (LRF) in the human.


Enzymatic synthesis of 2-keto-3-deoxy-d-glucose from D-gluconate.


Erythema annulare centrifugum coincident with Epstein-Barr virus infection in an infant.


Erythrocyte phosphoribosylpyrophosphate concentrations in heterozygotes for hypoxanthine-guanine phosphoribosyltransferase deficiency.


Erythrocytic galactokinase activity in neonatal and adult blood from various mammalian species.


Erythroleukemia in two infant chimpanzees fed milk from cows naturally infected with the bovine C-type virus.


Estradiol binding to rat corpora lutea during pregnancy.


Estrogen receptor in normal and neoplastic mouse mammary tissues.


Estrogen receptor interaction with the antitumor agent estradiol mustard.


Estrogen receptors: physiology and clinical applications.


Evidence for a dual central role for angiotensin in water and sodium intake.


Estrogenic regulation of uterine cyclic AMP metabolism.


Evidence for a structural interaction between ATP synthetase and cytochrome c oxidase in mitochondria.


Evidence for a subcellular vesicular site of collagen prolyl hydroxylation.


Evidence for common nucleotide sequences in the RNA subunits comprising Rous sarcoma virus 70 S RNA.


Evidence for the T cell specificity of sodium periodate-induced lymphocyte blastogenesis.


Evidence that adenosine 3', 5'-cyclic monophosphate is not involved in the growth response of prostate to androgens.


Evidence for persistence of infectious agents in isolated human populations.


Excretion of cyclic 3',5'-adenosine monophosphate in renal insufficiency and primary hyperparathyroidism after stimulation with parathyroid hormone.


Experiences in computer audiometry (ECoG and ERA).


Experimental encephalomyocarditis virus infection of pigs.


Explants, transplants and implants of a cartilage and bone morphogenetic matrix.


Extracellular current density analysis of responses in cerebellar cortex to mossy fiber activation.


Fabry's disease in a black man without skin lesions.


Fatty acids composition of very low density lipoprotein in psoriatic serum.


Fibroma regression in relation to antibody and challenge immunity to bovine papilloma virus.


Fibrous histiocytoma of the corneoscleral limbus.


Fine structure of rat carotid body after 6-methylprednisolone treatment.


Filter assay for 1alpha, 25-dihydroxyvitamin D3. Utilization of the hormone's target tissue chromatin receptor.


Evidence for myocardial conversion of angiotensin I.


Flank tumours in infants and children.

Flank tumours in infants and children.


Fluoride uptake from prophylactic dentifrices. IV. In vitro fluoride uptake from two different types of abrasive dentifrices.


Flash photolysis--electron spin resonance studies of the dynamics of photosystem I. 3. Temperature dependence of the decay of signal I.


Fractionation of plasma lipoproteins by density gradient centrifugation in swing-out rotors.


Functional classes of cells and their laminar distribution in monkey visual cortex.


Fructose-1,6-diphosphatase deficiency: another enzyme defect which can present itself with the clinical features of "tyrosinosis".


Functional organization of receptive fields in thalamic ventrobasal neurons examined by neuronal response to iterative electrical stimulation of skin.


Functional arginyl residues as NADH binding sites of alcohol dehydrogenases.


Further investigations of the expression of SV40-induced surface antigens subsequent to enzymatic treatment of transformed cells.


Further studies of histone phosphorylation in the presence of inhibitors of DNA synthesis.


Further studies on the accumulation and binding of androgen in rat epididymis.


Further studies on the stimulation of prostatic ribonucleic acid polymerase by x-5 alpha-dihydrotestosterone-receptor complexes.


Gangliosides of bovine optic nerve.

Gangliosides of bovine optic nerve.


Gas chromatographic estimation of hydroxyproline.


Gas-liquid chromatographic determination of vitamin D 2 in fortified full-cream dried milk.


Gastric leiomyoblastoma.

Gastric leiomyoblastoma.


General proteolytic activity of highly purified preparations of clostridial collagenase.


Genetic study on susceptibility of different mouse lines to ectromelia virus.


Genetic expression of aryl hydrocarbon hydroxylase activity. Induction of monooxygenase activities and cytochrome P1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically "nonresponsive" to other aromatic hydrocarbons.


Gas-chromatographic detection of isethionic acid in pig heart.


Giant cell tumour associated with rheumatoid arthritis.


Glomerular permeability to protein molecules--its possible structural basis.


Glomus tumour. A review of 15 clinical cases.


Generalized planar xanthomata associated with multiple myeloma and hyperlipoproteinemia.


Glucocorticoid receptors. Characteristics, specificity, and ontogenesis in embryonic chick neural retina.


Glucocorticoid-binding components in an irradiation-induced thymoma of the C57BL-6J mouse.


Glycogen metabolism in macrophages: effect of exogenous glycogen on glucogenesis in inflammatory exudate leukocytes and macrophages.


Glycolytic enzymes in muscle of the pacific dolphin: role of pyruvate kinase in aerobic-anaerobic transition during diving.


Gonadal androgen and sociosexual behavior of male mammals: a comparative analysis.


Granular cell myoblastoma lentiginosis profusa.


Gram-negative bacteria isolated from external eye infections.


Granular cell myoblastoma of the Larynx.


Granulated hydroxyapatite: preparation and chromatographic properties.


Growth and body composition in intrauterine growth retardation (IUGR) before and during human growth hormone administration.


Growth control in chick embryo fibroblasts; no evidence for a specific role for cyclic purine nucleotides.


Haem-haem interactions in cytochrome aa3 during the anaerobic-aerobic transition.


Hepatic artery ligation: adjunct in the management of massive hemorrhage from the liver.


Hepatocellular cacinoma; prolonged survival following resection.


Hepatocellular tolerance to carbon tetrachloride induced injury in the rat: a study of its nature and possible mode of evolution.


Herpes simplex-genitalis virus nonvirion antigens and their implication in certain human cancers: unconfirmed. The previously reported data on the existence of herpes simplex-genitalis virus nonvirion, neoantigens with distinctive properties, and on the presence of specific antibodies for these neoantigens only in the sera of specially hyperimmunized guinea pigs or of patients with certain types of cancer, could not be confirmed. Many factors that could have been responsible for the difference between the originally reported results and those recently obtained were carefully checked and investigated. The assumption that a mixture of two anticomplementary ingredients bound at least as much complement as the more anticomplementary component, and sometimes more, was found to be incorrect for the ingredients used in this work; the reverse was true. Previous failure to observe some of the strict requirements of the complement fixation test could account for some but not all of the unconfirmed previously reported data. Conclusions, based on the unconfirmed data, including those implicating these viruses in the etiology of certain human cancers, are therefore negated.


Heterogeneity and unusually high affinity in the interactions of adenosine 3':5'-monophosphate with specific binding proteins from liver and hepatoma cells.


High-molecular-weight DNA associated with intracytoplasmic A-particle inclusions.


Heterogeneity in the methylation and 5' termini of Novikoff ascites hepatoma 5.8 S ribosomal RNA.


Histochemical evidence of cyclic nucleotide phosphodiesterase in photoreceptor outer segments.


Histochemical observations on the enzymes of chicken yolk sac membrane.


Hormonal control of lipolysis in adipose tissue.


Hormonal control of oestrogen receptor in uterus and receptivity for ovoimplantation in the rat.


Hormone control of heme synthesis in cultures of human fetal liver cells.


Host defense mechanisms against infection with influenza virus. I. Effect of sensitized spleen cells on infection in vitro.


Housing for the disabled: a follow-up study.


Human cataract and galactose metabolism.


Hydatid cysts of the kidney. Simulating similar kidney lesions.


Hypercalcaemia of neoplasia, parathyroid hormone and vitamin D: studies in parabiosis.


Hyperpigmentation on cortisone after adrenalectomy for primary aldosteronism.


Hypercholesterolemia and hypertriglyceridemia in children. A pediatric approach to primary atherosclerosis prevention.


Hypnotic effects of L-tryptophan.

Hypnotic effects of L-tryptophan.


Hypolipidemic drugs and lipoprotein metabolism.


Hypothalamic control of secretion and release of prolactin.


Identification of a poison in toxic scallops from a Gonyaulax tamarensis red tide.


IgM antibodies specific for Epstein-Barr virus in infectious mononucleosis without heterophil antibodies. IgM antibodies specific for Epstein-Barr (E.B.) virus were demonstrable in all but one out of 46 patients diagnosed as having infectious mononucleosis wihout heterophil antibodies; cytomegalovirus aetiology was excluded. In all but two cases the highest titre was found in the first sample. In 21 patients a significant decrease was seen within a few weeks. IgG antibodies to E.B. virus, mostly remaining at a constant level, were demonstrable in all cases. IgM antibodies to E.B. virus were found in only five out of 300 controls.The results suggest that in a disease similar to infectious mononucleosis without heterophil antibodies testing of transient E.B. virus-specific IgM antibodies makes a rapid aetiological diagnosis possible and that in clinically well-defined cases viruses other than E.B. virus and cytomegalovirus are unlikely to be causal agents.


Identity of structure of ovine and bovine ACTH: correction of revised structure of the ovine hormone.


Imidazole derivatives as inhibitors of cyclic nucleotide phosphodiesterases.


Immunofluorescence staining for the diagnosis of herpes encephalitis. Direct immunofluorescence staining for herpes simplex virus was applied to cryostat sections of 43 specimens removed at brain biopsy. Herpes antigen was found in 10 specimens and virus was isolated from them. Antigen was found in one specimen from which virus was not isolated. Two specimens from which virus was isolated gave equivocal fluorescence. Thirty specimens gave no fluorescence or live virus. Immunofluorescence provided a diagnosis in three hr compared with 24-42 hr for virus isolation. Indirect immunofluorescence staining was applied to sections of brain removed at necropsy and fixed in formalin. Herpes antigen was found in sections of six of the 12 brains examined.


Immunopurification of phospholipase C (alpha-toxin) from Clostridium perfringens.


Immunological phagocytosis: effect of drugs on phosphodiesterase activity.


Implications of secretory immune system in viral infections.


Importance of age of host in detecting tumor-associated transplantation antigens.


Importance of testes in induction of hyperplastic nodules, carcinomas, and cirrhosis of liver in A times C male rats ingesting 0.025 percent N-2-fluorenyldiacetamide.


In situ characterisation of photosynthetic electron transport in Rhodopseudomonas capsulata.


In vivo subunit hybridization of succinic semialdehyde and 4-aminobutanal dehydrogenases from a Pseudomonas species.


Increase in the amount of iodide released from the thyroid after perchlorate or carbimazole administration.


Infectious diseases in children with cancer.


Increased collagen synthesis in blood vessels of hypertensive rats and its reversal by antihypertensive agents. Collagen synthesis is increased in the aortas, mesenteric arteries, and to a lesser extent, in the hearts of rats either made hypertensive with desoxycorticosterone acetate-salt or that are spontaneously hypertensive. Several markers of collagen biosynthesis were shown to be increased, including prolyl hydroxylase (EC 1.14.11.2; proline, 2-oxoglutarate dioxygenase), prolyl hydroxylase-related antigen, total collagen content, and the incorporation of [(3)H]proline into total protein and into collagen. The antihypertensive agents chlorothiazide and reserpine, when administered before the onset of hypertension in the rats treated with desoxycorticosterone acetate-salt, prevented or diminished the increase in collagen biosynthesis. When reserpine was given after the onset of hypertension, prolyl hydroxylase activity was decreased concomitant with the decrease in blood pressure. Treatment with reserpine is particularly effective in diminishing arterial prolyl hydroxylase activity.


Induction of respiratory-deficient mutants in a "petite negative" yeast species Kluyveromyces lactis with N-methyl-N'-nitro-N-nitrosoguanidine.


Infectious mononucleosis.

Infectious mononucleosis.


In vivo study of mechanism of propranolol-induced blockade or neuromuscular transmission.


Influenza virus antigen in postencephalitic parkinsonism brain. Detection by immunofluorescence.


Inhibition of human leucocyte collagenase by some drugs used in the therapy of rheumatic diseases.


Inhibition of interferon action by plant lectins.


Inhibition of platelet adherence to a collagen-coated surface by agents that inhibit platelet shape change and clot retraction.


Inhibition of membrane adenosine triphosphatase by alpha-tocopherol and its derivatives.


Inhibition of transport systems in cultured rat hepatoma cells by colcemid and ethanol.


Inhibitors against rabies virus present in normal rabbit sera.


Inhibitors of inositol cyclase (D-glucose 6-phosphate-1L-myoinositol 1-phosphate cycloaldolase) from rat testis.


Inferences from protein and nucleic acid sequences: early molecular evolution, divergence of kingdoms and rates of change.


Inhibitory action of thyroid hormone of the activation of adenyl cyclase-cyclic AMP system by thyroid-stimulating hormone in human thyroid tissues from euthyroid subjects and thyrotoxic patients.


Inhibitory effects of dibutyryl and cyclic AMP on the compound action potential in the frog (Rana pipiens) sciatic nerve.


Inhibitory processes and interneuronal apparatus in motor cortex during sleep and waking. I. Background firing and responsiveness of pyramidal tract neurons and interneurons.


Inhibitory processes and interneuronal apparatus in motor cortex during sleep and waking. II. Recurrent and afferent inhibition of pyramidal tract neurons.


Intensive transfusion therapy in thalassemia major: an eight-year follow-up.


Interaction between dehydroepiandrosterone, cyclic adenosine-3',5'-monophosphate and glucose-6-phosphate-dehydrogenase in normal and diseased subjects.


Interaction of angiotensin peptides and of amino acids with p-nitrophenyl acetate.


Interaction of human serum high density lipoprotein apoprotein with phospholipids.


Interaction of manganous ion, substrates, and anions with arginine kinase. Magnetic relaxation rate studies of water protons and kinetic anion effects.


Interactions between the prostaglandins and steroid hormones.


Intravenous nutrition of newborn infants with lipid.


Intussusception as a complication of malignant neoplasm.


Ion pair partition chromatography in the bioanalysis of alprenolol-(3H) and alprenolol metabolites.


Iodinated derivatives of adrenocorticotropic hormone. Preparation of iodinated alpha 1-24-ACTH with full hormonal activity.


Is chloramphenicol the drug of choice for the treatment of enteric fever? Comparative studies on the effects of chloramphenicol, trimethoprim-sulphametoxazole and beta-lactam antibiotics.


Isolation and characterization of bovine parainfluenza type 3 virus from cattle in Kenya.


Interaction of neomycin with phosphoinositide metabolism in guinea pig inner ear and brain tissues.


Isolation and analysis of human plasma lipoproteins accumulating postrandial in an intermediate density fraction (d 1.006--1.019 g-ml).


Isolation and fractionation of porcine peripheral lymphocytes.


Isolation and identification of an O-(2-hydroxypropyl)-maltose from the faeces of rats fed with O-(hyroxypropyl)starch.


Isolation and properties of protein component as activator for anthranilamide hydroxylation in rat liver.


Interferon production by lymphocytes from patients with systemic lupus erythematosus.


Isolation and protein pattern of eye lens fiber junctions.


Isolation of plasma membranes from normal and 1-beta-D arabinofuranosylcytosine transformed hamster embryo fibroblasts.


Kinetic and molecular properties of lysine-sensitive aspartokinase. Factors influencing the lysine-mediated association reaction and their relationship to the cooperativity of lysine inhibition.


Kinetic studies of the oxidation of ferrocytochrome c from horse heart and Candida krusei by tris(1,10-phenanthroline)cobalt(3).


Kinetics and electron paramagnetic resonance spectra of vanadyl(IV) carboxypeptidase A.


Labeling of the external surface of hamster and mouse fibroblasts with (14C)sialic acid.


Lactate stimulation of renal cortical adenylate cyclase: a mechanism for erythropoietin production following cobalt treatment or hypoxia.


Laboratory test results altered by "The Pill".


Late field responses in optic tectum of the pigeon.


Lead neuropathy and sickle cell disease.


Letter: Alcohol and alpha-lipoprotein cholesterol.


Letter to the editor: Differences between in vivo and in vitro actions of prostaglandins in corpus luteum: is there a paradox?


Letter: Assay for carcinoembryonic antigen.


Letter: Congenital mesoblastic nephroma.


Letter: Diagnosis of insulinomas.

Letter: Diagnosis of insulinomas.


Isolation of infectious DNA from avian myeloblastosis virus transformed leukemic cells.


Letter: Experimental infection of a horse with an equine adenovirus.


Letter: Glioblastoma multiforme.

Letter: Glioblastoma multiforme.


Letter: Immobilization of trypsin on partially oxidized cellulose.


Letter: Malabsorption in overland travellers to India.


Letter: Nutrient deficiencies after intensive parenteral alimentation.


Letter: Indomethacin, prostaglandin and hypercalcemia.


Letter: NAD and chronic schizophrenia.

Letter: NAD and chronic schizophrenia.


Letter: On continuity of care.

Letter: On continuity of care.


Letter: Other causes of petechiae.

Letter: Other causes of petechiae.


Letter: Photoinactivation therapy and herpes simplex.


Letter: Tinel's sign and Laplace's Law.

Letter: Tinel's sign and Laplace's Law.


Letter: The oncogenic potential of dye-light treatment of herpetic lesions.


Letter: Viscosity of cellular protoplasm: what do spin probes tell us?


Letter: Zoster in families.

Letter: Zoster in families.


Light, electron microscopical, and histochemical study of motor nerve cells in spinal cord of hibernating and non-hibernating hedgehog.


Lipid phase transitions in membrane vesicles from Thermoplasma acidophila.


Lipolysis, aging, and hormones.

Lipolysis, aging, and hormones.


Lipoprotein fractions in maternal, cord and newborn serum.


Lipolytic effects of sheep beta-lipotropin in rat adipose tissue: interaction with theophylline and dihydroergotamine.


Lipoprotein lipase: comparative properties of the membrane-supported and solubilized enzyme species.


Lipoproteins and lipids in diabetics with and without coronary heart disease.


Liver disease in transplanted patients.

Liver disease in transplanted patients.


Local, reflex, and central commands controlling gill and siphon movements in Aplysia.


Localization of alpha-fetoprotein by immunofluorescence in hyperplastic nodules during hepatocarcinogenesis induced by 2-acetylaminofluorene.


Location of intrahypothalamic estrogen-responsive sites influencing LH secretion in the female Rhesus monkey.


Linoleate oxidation products and cardiovascular lesions.


Lung cancer: assessment and selective management.


Lumbar myelography and adhesive arachnoiditis.


Luteotrophic factors in the cow: evidence for LH rather than prolactin.


Magnetic resonance study of spin-labelled rhodopsin.


Malignant lymphoma with intracytoplasmic IgM crystalline inclusions.


Malignant mesenchymal tumors of the uterine corpus.


Mammographic varicosities indicative of a superior mediastinal syndrome. A case report.


Malignant tumours following immunosuppression in renal transplantation.


Marine sterols. V. Isolation and structure of occelasterol, a new 27-norergostane-type sterol, from an annelida, Pseudopotamilla occelata.


Maternal adrenocorticotrophic hormone and cortisol during labour and vaginal delivery.


Measurement of angiotensin II in an ultrafiltrate of plasma.


Mechanism of adenosine triphosphate-dependent Ca2+ uptake of brain microsomes.


Mechanisms controlling maternal placental circulation.


Mechanisms of drug action on recovery processes of cardiac muscle in myocardial infarction.


Mechanisms of hyperlipoproteinemia.

Mechanisms of hyperlipoproteinemia.


Mechanisms of steroid resistance.

Mechanisms of steroid resistance.


Mechanisms of insulin action.

Mechanisms of insulin action.


Metabolic regulation of steroidogenesis in isolated adrenal cells of rat. Effect of actinomycin D on cGMP-induced steroidogenesis.


Mechanisms underlying vasomotor regulation of regional pulmonary blood flow in normal and disease states.


Metabolic regulation of steroidogenesis in isolated adrenal cells of the rat. ACTH regulation of cGMP and cAMP levels and steroidogenesis.


Methionine metabolism in pyridoxine deficiency.


Microcirculatory effects of prostaglandins E1, E2, and A1 in the rat mesentery and cremaster muscle.


Mitochondrial membranes of inositol-requiring Saccharomyces carlsbergensis: covalent binding of a radioactive marker to the outer membrane.


Mode of action of chronotropic agents in cardiac Purkinje fibers. Does epinephrine act by directly modifying the external surface charge? Hauswirth et al. (1968) proposed that epinephrine acts on i(KK2) by adding its own positive charge to the external membrane surface near the i(KK2) channel. This hypothesis was tested by using noncationic compounds, theophylline and R07-2956, which mimicked epinephrine's effects on pacemaker activity and on i(KK2). In maximally effective doses, theophylline or R07-2956 occluded the effect of epinephrine, indicating a shared final common mechanism. Since theophylline and R07-2956 are noncationic at pH 7.4, the common mechanism cannot be a direct change in external surface charge. On the contrary, epinephrine does not interfere with the voltage shift produced by La(+++), which is thought to modify the external surface charge. The results argue against the original hypothesis but leave open the possibility that an alteration in internal surface charge generates the observed voltage shift. The potency of theophylline and R07-2956 as phosphodiesterase inhibitors suggests that the final common mechanism begins with the elevation of intracellular cyclic AMP, leading to a saturable process which limits the voltage shift's magnitude. This hypothesis is used to generate dose-response curves describing the combined effects of epinephrine and theophylline, and these are compared with experimental data.


Mode of action of cholera toxin: stabilization of catecholamine-sensitive adenylate cyclase in turkey erythrocytes. Preincubating turkey erythrocytes with cholera toxin alters their adenylate cyclase (EC 4.6.1.1) system: basal activity, maximal epinephrine-stimulatable activity, and affinity of the enzyme reaction for epinephrine are all increased. Pretreatment of erythrocytes with choleragenoid prevents these changes. Cholera toxin does not alter [(3)H]epinephrine uptake by intact erythrocytes. The increase in epinephrine-stimulatable cyclase activity appears to occur at the expense of fluoride-stimulatable activity, which is decreased by the toxin. In lysates from both toxin-treated and control cells, maximally stimulating amounts of epinephrine and fluoride, when added in combination, have a nearly additive effect on cyclase activity. These observations suggest that the adenylate cyclase system of the turkey erythrocyte may exist in two interconvertible forms, one that is catecholamine-responsive but fluoride-insensitive, and another that is fluoride-sensitive but not coupled to catecholamine receptors. Cholera toxin appears to stabilize the enzyme in its hormone receptor-coupled form.


Modification of neuron properties by electrotonic synapses. II. Burst formation by electrotonic synapses.


Modification of neuron properties by electrotonic synapses. I. Input resistance, time constant, and integration.


Model of molecular mechanism able to generate a depolarization-hyperpolarization cycle.


Middle ear masses mimicking glomus tumors: radiographic and otoscopic recognition.


Modulation of malate dehydrogenase of young and old rats by various effectors.


Monovalent cation requirement for ADP inhibition of pyruvate dehydrogenase kinase.


Multiple forms of cyclic 3',5'-AMP phosphodiesterase of rat cerebrum and cloned astrocytoma and neuroblastoma cells.


Multiple glomus tumours.

Multiple glomus tumours.


Mutagenic action of methyl methane sulphonate on the bluegreen alga Anacystis nidulans.


Murine sarcoma virus gene expression: transformants which express viral envelope glycoprotein in the absence of the major internal protein and infectious particles. Expression of the major internal protein and the envelope glycoprotein of murine C-type viruses in focus-derived lines of normal rat kidney cells infected with Kirsten murine sarcoma virus was measured by radioimmunoassay. Of the clones selected, which do not produce virus particles or the major viral structural protein, approximately half express the viral envelope glycoprotein at concentrations found in productively infected cells. Expression of the envelope glycoprotein did not appear to alter significantly the properties of the transformed cells in culture.


Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells.


Myoepithelioma of the parotid gland.

Myoepithelioma of the parotid gland.


Neoplasms of the kidney, renal pelvis and ureter. A study of 92 primary and 44 metastic tumours.


Multicentric reticulohistiocytosis. Fine structural analysis of the synovium and synovial fluid cells.


Nephroblastoma with keratinising cysts--(a case report).


Network analysis as a method for the evaluation of service delivery systems.


Nephrotic syndrome with oat-cell carcinoma.


Neuroblastoma: drug-induced differentiation increases proportion of cytoplasmic RNA that contains polyadenylic acid. The production of cytoplasmic RNA that contains polyadenylic acid is increased, relative to total cytoplasmic RNA, in a neuroblastoma clone, NBE-(A), after induction of differentiation by 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone, an inhibitor of adenosine 3',5'-monophosphate phosphodiesterase. The amount of RNA that contains polyadenylic acid in cytoplasm may be greater in such differentiated neuroblastoma cells than in proliferating control cells.


Neuronal activity before and during eye movements in thalamic internal medullary lamina of the cat.


Night terrors.

Night terrors.


New serotypes of reoviruses isolated from cattle.


Neural origin of granular cell tumor.

Neural origin of granular cell tumor.


Non-productive infection of genetically resistant mouse cells by murine cytomegalovirus.


Non-specific immunostimulation in bronchogenic cancer.


Nuclear bodies in endothelial cells of human glomeruli.


Nuclear coupling of 33S and the nature of free radicals in irradiated crystals of cystine dihydrochloride. The (33)S hyperfine structure has been observed and analyzed in the electron spin resonance of gamma-irradiated single crystals of cystine dihydrochloride at 77 degrees K and at room temperature. The radicals observed at room temperature and previously assigned as RCH(2)S are proved to be disulfide radicals, RCH(2)SS. However, the RCH(2)S radical is identified by the (33)S measurements in samples irradiated at 77 degrees K, annealed at 200 degrees K, and observed at 77 degrees K. This monosulfide radical appears to undergo reactions to form disulfide radicals at room temperature.


New approaches to the evaluation and treatment of insomnia. (Preliminary results).


Nuclear magnetic resonance studies of cancer. V. Appearance and development of a tumor systemic effect in serum and tissues.


Nuclear poly (ADPR) and mono (ADPR) residues in tissues with different growth rates.


Nuclear magnetic resonance titration curves of histidine ring protons. V. Comparative study of cytochrome c from three species and the assignment of individual proton resonances.


Nucleoside peptides. 6. Synthesis of certain N-(5-amino-1-(beta-D-ribofuranosyl)imidazole-4-carbonyl)amino acids related to naturally occurring intermediates in the purine biosynthetic pathway.


Nutrient media for plant-parasitic nematodes. VI. Nucleic acids content and nucleotide synthesis in Aphelenchoides rutgersi.


Observations on experimental infection with infectious bovine rhinotracheitis virus in rabbits.


Observations and comments on two outbreaks of abortion associated with IBR virus infection.


Observations on the first epidemic of foot-and-mouth disease type SAT 1 in Tanzania.


Ocular manifestations of the mucopolysaccharidoses.


Olivopontocerebellar degeneration. Clinical and ultrastructural abnormalities.


On the limited peptic digestion of horse heart cytochrome C. isolation of C-terminal peptide sequences.


On the luminescence of estrogens.

On the luminescence of estrogens.


On the mechanism of uptake of iron by reticulocytes.


On the polypeptide composition of an abnormal high density lipoprotein (LP-E) occurring in LCAT-deficient plasma.


Oncogenic activity of an m-dioxane derivatives: 2,6-dimethyl-m-dioxan-4-ol acetate (dimethoxane).


On the relation of products of activated lymphocytes to cell-mediated cytolysis. Experiments have been designed to test the hypothesis that soluble mediator production and T-cell-mediated cytotoxicity are necessarily related phenomena, and that soluble mediators may be involved in the mechanism of cytolysis. To this end, agents known to inhibit T-cell-mediated lysis in vitro have been studied for their effects on the production of two lymphocyte-derived mediators, lymphotoxin (LT) and migration inhibitory factor (MIF). A clear dissociation between mediator production and cell-mediated cytolysis was found using inhibitors of protein synthesis. Pactamycin and emetine, in doses of 10(-7) M to 10(-6) M, suppressed production of MIF and LT with only slight effect on killing of mastocytoma cells by immune T cells. On the other hand colchicine and vinblastine inhibited T-cell-mediated cytolysis in a dose-related manner but had no significant effect on either MIF or LT production, A striking dichotomy was also observed after augmentation of intracellular cyclic 3'5' adenosine monophosphate (cAMP) levels with cholera enterotoxin. Increased cAMP levels were associated with abrogation of direct lytic activity, but were without significant effect on MIF or LT production in guinea pigs or mice. These findings indicate that mediator production and direct lymphocyte-mediated cytolysis can be experimentally dissociated and represent independent cell-mediated immune functions.


Ontogeny of thirst in the rat: effects of hypertonic saline polyethylene glycol, and vena cava ligation.


Oocyte maturation and follicle cell viability in vitro.


Organizational and attitudinal correlates of citizen board accomplishment in mental health and retardation.


Osteodystrophy of dialysed patients treated with vitamin D.


Paradoxical sleep in the chick (Gallus domesticus).


Parathyroid hormone deficiency with Albright's hereditary osteodystrophy.


Partial purification and characterization of the SV40 T antigen.


Partial purification of human interferon by affinity chromatography. Human interferon prepared by challenge of leukocytes with Sendai virus, or of fibroblasts with double-stranded poly(inosinic acid).poly(cytidylic acid), has been studied with respect to purification by affinity chromatography. Both leukocyte and fibroblast interferons are removed from crude tissue culture fluids by means of columns of antibody to leukocyte interferon attached to Sepharose-4B. The antibody was prepared in sheep using, as antigen, material that had been partially purified by gel filtration through Sephadex G-100 columns. Many of the impurities in the crude fibroblast interferon were presumably not recognized by the sheep antibodies induced by leukocyte interferon. Fibroblast interferon was, therefore, much more effectively purified as the result of this "common denominator" approach. The fibroblast product, in contrast to interferon from leukocytes, could only be harvested efficiently from the crude starting material when a carrier protein (bovine-serum albumin, and later, cytochrome c) was added to the eluting buffers to counteract losses, presumably due to adsorption on purification and assay equipment. Both varieties of interferon exhibit molecular weights of approximately 20,000-25,000, although association with higher molecular weight proteins occurs.


Partial purification and reconstitution of the heme oxygenase system from pig spleen microsomes.


Pathological studies on adenocarcinoma of the uterine cervix in Singapore.


Percutaneous needle aspiration lung biopsy.


Peripheral modification of thermoregulatory function during heat acclimation.


Pharyngoesophageal dysphagia and recurrent laryngeal nerve palsy.


Persistent noncytocidal vesicular stomatitis virus infections mediated by defective T particles that suppress virion transcriptase. Infectious B virions of vesicular stomatitis virus were 100% lethal to BHK(21) (baby hamster kidney) cells when infecting alone, and persistent noncytocidal infection could not be achieved with cloned B virions alone. However, a mixture of B virions and homologous, short, defective, interfering particles (T particles) of a temperature-sensitive mutant of the virus regularly established persistently infected, noncytocidal carrier cultures. A long T particle was generated during establishment of the carrier culture; we show that this long T particle can establish and maintain persistent noncytocidal infection even when it infects cells along with virulent wild-type B virions. This long T particle causes the production of wild-type B virions with greatly reduced virion transcriptase (EC 2.7.7.6; RNA nucleotidyltransferase) levels when coinfecting the same cells, so it appears to prevent cytopathology by regulating virus transcription. The implications of these findings for rabies and other slowly progressing noncytocidal infections are discussed.


Phospholipid metabolism in the eggs and embryos of the sea urchin Arbacia punctulata.


Phospholipid compositon of mitochondria and microsomes from regenerating rat liver and hepatomas of different growth rate.


Phosphorylation of acid-soluble proteins in isolated nucleoli of Novikoff hepatoma ascites cells. Effects of divalent cations.


Photophosphorylation not coupled to DCMU-insensitive photosystem II oxygen evolution.


Physical-chemical studies of phospholipids and poly (amino acids) interactions.


Physiological and biochemical properties of neuromuscular transmission between identified motoneurons and gill muscle in Aplysia.


Physiological properties of developing frog tadpole nerve-muscle junctions during repetitive stimulation.


Plasma adenosine 3',5'-monophosphate in antiinsulin-treated rats.


Plasma aldosterone during haemodialysis in patients with terminal renal failure.


Plasminic activity and emotional stress.


Platelet factor-3 availability and the platelet release reaction.


Platelets as a source of fibroblast growth-promoting activity.


Pneumocystis carinii pneumonia.

Pneumocystis carinii pneumonia.


Poliomyelitis vaccination in Thailand. I. A pilot study of the administration of live poliomyelitis vaccine.


Polymorphism of adenylate kinase (AK) and adenosine deaminase (ADA) in the Polish population.


Poly(ADP-ribose): release of template restriction in HeLa cells. Evidence is presented to show that ADP-ribosylation of nuclear proteins by poly(ADP-ribose) polymerase enhances template-primer activity of HeLa cell nuclear DNA. We used Escherichia coli DNA polymerase I (EC 2.7.7.7; DNA nucleotidyltransferase) as an exogenous probe of nuclear DNA status. Neither NAD nor free poly(ADP-ribose) acts directly on the bacterial enzyme. The stimulation is specific for formation of ADP-ribosylated proteins and is not a generalized polyanion or nucleotide effect on chromatin. The release of template restriction is proportional to the capacity of a given cell line to synthesize poly(ADP-ribose); both the stimulation and poly(ADP-ribose) formation are coordinately proportional to NAD concentration. Binding studies with DNA polymerase indicate exposure or generation of additional 3'-OH primer sites due to ADP-ribosylation in intact nuclei. With intact cells, there appears a correlation among growth, physiological template restriction, and the above effects of ADP-ribosylation.


Polysaccharide synthesis on immobilized phosphorylase.


Potential antitumor agents. 10. Synthesis and biochemical properties of 5-N-alkylamino-,N,N-dialkylamino-, and N-alkylacetamido-1-formylisoquinoline thiosemicarbazones.


Potential antitumor agents. 11. Inhibitors of alkaline phosphatase, an enzyme involved in the resistance of neoplastic cells to 6-thiopurines.


Power spectral density of hippocampal theta activity during rhombencephalic sleep, after physostigmine administration and during orienting reaction.


Preparation of microcells by enucleation of micronucleate cells.


Presence of two active X chromosomes in hybrids between normal human and SV40-transformed fibroblasts from patients with the Lesch-Nyhan syndrome.


Presence of repeating sub-sequences and symmetry patterns in proteins.


Presynaptic inhibition: primary afferent depolarization in crayfish neurons. Inhibition of transmission between tactile sensory neurons and interneurons in the crayfish was investigated by intracellular recording int the presynaptic processes. Inhibition is correlated with a depolarization of the presynaptic process, as in the mammalian spinal cord; the depolarization is accompanied by a conductance increase, and is mediated by interneurons that can be excited by a variety of routes.


Prevention and treatment; a stategy for survival.


Preventive maintenance for mentally ill patients.


Problem solving: waking and dreaming.

Problem solving: waking and dreaming.


Primary breast and lung carcinoma in the same patient.


Primary type V hyperlipoproteinaemia (mixed hyperlipaemia): successful response to dietary restriction and simfibrate.


Proceedings: A possible origin of the 'giant' spontaneous potentials that occur after prolonged transmitter release at frog neuromuscular junctions.


Proceedings: Benign tumours of the kidney in infancy.


Proceedings: Azurophil and specific granules of blood neutrophils in chronic myelogenous leukaemia: and ultrastructural and cytochemical analysis.


Procollagen: intermediate forms containing several types of peptide chains and non-collagen peptide extensions at NH2 and COOH ends. A population of procollagen molecules has been isolated from the culture medium of a clonal line of calf dermatosparactic cells and shown to have the amino-acid composition, physical properties, and molecular structure consistent with collagen precursors. Although this procollagen population shares immunologic determinants with the procollagen obtained from dermatosparactic skin, it differs from the latter in aminoacid composition, in subunit properties, and by its content of both amino and carboxyl terminal non-collagen peptide appendages. We propose that the cell culture procollagen contains earlier biosynthetic forms of dermatosparactic procollagen.


Prolactin release in cattle.

Prolactin release in cattle.


Prevalence of asymptomatic femoral artery atheromas in hyperlipoproteinemic patients.


Progesterone receptors of chick oviduct. Steroid-binding "subunit" formed with divalent cations.


Propagation of mouse cytomegalovirus in murine renal epithelium.


Properties of enucleated cells. II. Characteristic overlapping of transformed cells is reestablished by enucleates.


Prostaglandin inhibition of cyclic-AMP accumulation and rate of lipolysis in fat cells.


Properties of the specific binding of 125I-nerve growth factor to responsive peripheral neurons.


Prostaglandin synthesis in rabbit graafian follicles in vitro. Effect of luteinizing hormone and cyclic AMP.


Prostaglandin F production in vitro by granulosa cells from rabbit pre-ovulatory follicles.


Prostaglandin 15-hydroxy dehydrogenase and delta13 reductase levels in the lungs of maternal, fetal and neonatal rabbits.


Proton equilibria and kinetics in the liver alcohol dehydrogenase reaction mechanism.


Protein metabolism in hypertrophied heart muscle.


Purification of a ribonuclease inhibitor from Novikoff hepatoma supernatant fraction.


Pseudohypoparathyroidism type II: restoration of normal renal responsiveness to parathyroid hormone by calcium administration.


Purification and characterization of anti-A agglutinin from Euhadra callizoma amaliae.


Pyruvate oxidation in neuromuscular diseases. Evidence of a genetic defect in two families with the clinical syndrome of Friedreich's ataxia.


PGF-2 alpha-induced loss of corpus luteum gonadotrophin receptors.


Radiation effects and adrenal cortex. VII. Corticosteroid changes in mice following whole-body irradiation.


Radioimmunoassay of the major group specific protein of endogenous baboon type C viruses: relation to the RD-114-CCC group and detection of antigen in normal baboon tissues.


Quantitative studies of the inhibitory effect of perchlorate on the concentration of 36C1O minus 4 125I minus and 99mTcO minus 4 in salivary glands of male and female mice.


Rapid estimation of small amounts of formaldehyde liberated during periodate oxidation of a sialoglycoprotein.


Rapid separation of tumor-promoting agents, phorbol and phorbol myristate acetate (12-o-tetradecanoylphorbol-13-acetate) by high-pressure liquid chromatography.


Rates of disappearance from blood and biological potencies of mammalian gonadotropins (HCG and ovine LH) in the toad Bufo bufo bufo (L.).


Reaction center bacteriochlorophyll triplet states: redox potential dependence and kinetics.


Recent work on virus diseases.

Recent work on virus diseases.


Receptive fields and response properties of mechanoreceptor neurons innervating siphon skin and mantle shelf in Aplysia.


Recognition of TMV RNA by the tRNA nucleotidyltransferase.


Recurrent idiopathic polyneuropathy.

Recurrent idiopathic polyneuropathy.


Reconstituted hamster liver microsomal enzyme system for N-hydroxylation of the carcinogen 2-acetylaminofluorene.


Recurrent paroxysmal nonepileptic disorders.


Red chorda tympani nerve and Bell's palsy.


Reduction of ferricytochrome c by hydrogen atoms: evidence for intramolecular transfer of reducing equivalent.


Reduced aldosterone secretion during spironolactone treatment in primary aldosteronism: report of a case.


Regional diversity in excitatory and inhibitory receptive-field organization of cat thalamic ventrobasal neurons.


Regulation of protein phosphorylation and membrane permeability by beta-adrenergic agents and cyclic adenosine 3':5'-monophosphate in the avian erythrocyte.


Rejection of mammary adenocarcinoma cell tumors and the prevention of progressive growth of incipient metastases following intratumor permeation with killed Bordetella pertussis.


Regulation of renal circulation during behavioral changes in the cat.


Relation between rhythmical hippocampal ("theta") and olfactory (breath) EEG activity during spontaneous behaviour and REM sleep in rats.


Relationship of calcium uptake and calcium-binding protein synthesis in chick and rat intestine in response to Solanum malacoxylon.


Relationship of glucose metabolism to adrenergic transmission in rat mesenteric arteries. Effects of glucose deprivation, glucose metabolites, and changes in ionic composition on adrenergic mechanisms.


Release of kallikrein from isolated cellular organelles of the rat submandibular salivary gland.


Renal neoplasms in children.

Renal neoplasms in children.


Renin release by rat kidney slices in vitro: effects of cations and catecholamines.


Reo-like neonatal calf diarrhoea (NCD) virus demonstrated in Denmark.


Repetitive patterns of metabolic changes during cortical spreading depression of the awake rat.


Replication of arboviruses in mouse organ cultures. I. Results with Middelburg virus in organ cultures and peritoneal macrophages.


Reduction of serum triglyceride levels by polyunsaturated fat. Studies on the mode of action and on very low density lipoprotein composition.


Representation of the course of an outbreak of contagious bovine pleuro-pneumonia in a sedentary herd of humpless cattle.


Report from Sloan-Kettering Institute. Enzyme therapy and nutritional depletion of tumors.


Requirement of 3'-terminal poly(adenylic acid) for the infectivity of poliovirus RNA. Ribonuclease H (EC 3.1.4.34) has been used to remove selectively much of the 3'-terminal poly(adenylic acid) [poly(A)] from poliovirus RNA by treating the RNA with the enzyme in the presence of poly(dT). Over 80% of the poly(A) could be removed and the residuum was found as oligo(A) stretches attached to many or all of the viral RNA molecules. Reduction of the size of the poly(A) markedly decreased the specific infectivity of poliovirus RNA, indicating that poly(A) is necessary to the infectivity of the RNA. The virions in plaques deriving from infection with treated RNA have a normal amount and size of poly(A), indicating that mechanisms exist in infected cells to regenerate normal length poly(A) from truncated poly(A).


Reserve of vasopressin-sensitive adenylate cyclase in toad urinary bladder.


Requirement for double-stranded RNA during the in vitro synthesis of RNA by foot-and-mouth disease virus replicase.


Residential facilities for hospital-discharged former mental patients. Aspects in development.


Response of chick-embryo kidney cells in vitro to two avian tumor viruses.


Rheumatic manifestations of hypophosphatemia.


Ribonucleotides in newly synthesized DNA of herpes simplex virus.


Riboflavin metabolism in cancer.

Riboflavin metabolism in cancer.


Rifamycin derivatives as inhibitors of a ribonucleic acid instructed deoxyribonucleic acid polymerase function. Effect of lipophilicity.


Role of enzyme interactions in the regulation of gluconeogenesis. Modification of the binding properties of fructose 1,6-diphosphatase by adenosine monophosphate, adenosine triphosphate, and fructose 1,6-diphosphate.


Role of deoxyribonucleic acid-ribonucleic acid hybrids in eukaryotes. Study of the template requirements of yeast ribonucleic acid polymerases and nature of the ribonucleic acid product.


Rotator cuff tear versus suprascapular nerve injury: a problem in differential diagnosis.


Schistosomatium douthitti: effects of thyroxine.


Screening and genetic counseling programs for sickle cell trait and sickle cell anemia.


Screening tests for renovascular hypertension--an appraisal.


Selection of hormone-dependent breast cancers.


Selective inhibition of the synthesis of single-stranded RNA of encephalomyocarditis virus by 2-(alpha-hydroxybenzyl)-benzimidazole in cell-free systems.


Secretion rates and chemical composition of oviduct and uterine fluids in sows.


Responses of resistance and capacitance vessels in feline nasal mucosa to vasoactive agents.


Selective thymic localization of murine leukemia virus-related antigens in C57BL-Ka mice after inoculation with radiation virus. The tissue distribution and extent of virus-specific antigen expression were studied by immunofluorescence as a function of time and of lymphoma development in adult C57BL/Ka (Fv-1(b)) mice after intravenous injection of radiation leukemia virus, a B-tropic murine leukemia virus. Viral antigens were detected earlier in the thymus (1 week) than in the bone marrow, spleen, or lymph nodes (2-3 weeks). Despite an initial virus-induced thymic involution, the percentage of immunofluorescence-positive cells in the thymus rapidly increased thereafter to 65-80%, at which level it remained until 9 weeks, at which time increases in size and weight, histological changes, and an increased number of blastoid cells indicated the onset of lymphoma development in the thymus. In contrast, the percentage of immunofluorescence-positive cells in the bone marrow, spleen, and nodes remained low, and gradually decreased to zero within 8 weeks after thymectomy. The selective thymic localization of antigens induced by radiation leukemia virus in C57BL/Ka mice is in striking contrast to the previously reported ubiquitous tissue distribution of the Gross-AKR virus, an N-tropic virus, in its natural host, the Fv-1(n), AKR strain with a high incidence of leukemia.


Sensation and sensibility in the upper extremity.


Sensitivity of target cells to the cytotoxic effects of lymphocytes induced by interferon.


Sensory transmission through lemniscal pathway during voluntary movement in the cat.


Separation of amino acids from untreated urine on thin layers of silica gel.


Separation of newly synthesized nucleohistone by equilibrium centrifugation in cesium chloride.


Septal hyperdipsia: specific enhancement of drinking to angiotensin in rats.


Serological examination of a sample of human population and some animal species for the presence of antibodies to Yaba 1 virus.


Serum and tissue lipid metabolism and effect of nicotinic acid in different types of hyperlipidemia.


Serum lipoprotein abnormalities in patients with ischaemic heart disease: comparisons with a control population. The frequency and nature of abnormalities of serum lipoproteins have been studied, using quantitative techniques, in 143 patients with ischaemic heart disease (I.H.D.). Rigorous selection criteria were used. The findings were related to the distribution of lipoprotein concentrations in a carefully screened control population. Hyperlipoproteinaemia occurred in 55% of patients and in 11 out of 15 patients aged less than 40 years. Raised triglyceride and cholesterol concentrations in very low density lipoprotein were the most frequent abnormalities followed by raised cholesterol content of low density lipoprotein. In young patients high density lipoprotein levels were subnormal. Hyperlipoproteinaemia of W.H.O. types IIa, IIb, III, IV, and V all seemed to be over-represented in I.H.D. I.H.D. patients with type IIa, IIb, and IV abnormalities were all significantly younger than I.H.D. patients with normal lipoprotein levels.


Short length amino acid sequence homology among ancestrally unrelated proteins.


Serum lipoproteins and coronary heart disease.


Similar effects of calitonin, insulin and somatomedin A on lipolysis and uptake of calcium and glucose in rat adipose tissue in vitro.


Sialyl transferase activities of rat ascites hepatoma cells and rat liver.


Skeletal maturation of the hand and wrist of young children in Baghdad.


Simultaneous stimulation test for the anterior pituitary hormones.


Simultaneous evaluation of the pituitary reserve of GH, TSH, ACTH and LH in children.


Sleep of depressed patients in remission.


Sleep-associated growth hormone (GH) release in schizophrenia.


Society pays for the learning disabled.

Society pays for the learning disabled.


Slow evolution of transferrin and albumin in birds according to micro-complement fixation analysis.


Solvent isotope effects on the structure and function of mitochondrial membranes in aqueous media.


Some chemical and stereochemical modifications of the erythromycin lactone rings.


Some in vivo interactions of oestradiol with the mouse vagina.


Some peculiarities of metabolism of the myocardium under conditions of experimental disturbance of the microcirculation.


Specific binding of 8-anilinonaphthalene sulfonate to diphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart.


Specificity of ribonucleic acid chain initiation by bacteriophage T3-induced ribonucleic acid polymerase.


Spectral characterization of 15N spin labels.


Spinal and supraspinal factors in the control of voluntary activity under normal and pathological conditions.


Statistical quality control and routine data processing for radioimmunoassays and immunoradiometric assays.


Stereotactic Curie-therapy of pituitary adenomas. A long-term follow-up study.


Steroid hormones and breast cancer.

Steroid hormones and breast cancer.


Some recent advances in virilizing and feminizing syndromes and hirsutism.


Stimulated formation of cyclic adenosine 3':5'-monophosphate by aspartate and glutamate in cerebral cortical slices of guinea pig.


Stimulation of the synthesis of very low density lipoproteins in rooster liver by estradiol.


Stochastic models for single neuron firing trains: a survey.


Stimulation of vascular smooth muscle sodium, potassium--adenosinetriphosphatase by vasodilators.


Stress and the hormonal regulation of the immune response in mice.


Stress, insulin antagonist and transient diabetes mellitus in the rat.


Structural investigation of oxalate-soluble rapeseed (Brassica campestris) polysaccharides. 3. An arabinan.


Studies on an extracellular coat of mammalian sperm with reference to its DNA content.


Structure of yeast hexokinase. 3. Low resolution structure of a second crystal form showing a different quaternary structure, heterologous interaction of subunits and substrate binding.


Studies on feline lymphosarcoma in the Sydney area.


Studies on lipid and fatty acid composition of human hepatoma tissue.


Studies on the conformational changes of metalloproteins induced by electrons in water-ethylene glycol solutions at low temperatures. Cytochrome C.


Studies on the angiotensin II receptor in the zona glomerulosa of the rat adrenal gland.


Studies on the differential response to glucagon concentration on gluconeogenesis in isolated hepatocytes containing high and low glycogen.


Studies on the metabolism of ATP by isolated bacterial membranes: role of succinyl CoA synthetase in diglyceride kinase activity.


Studies on the mechanism of action of udp-D-glucose dehydrogenase from beef liver. II.


Studies on vitamin D and its analogs. I. Synthesis of 1alpha-hydroxycholest-5-ene.


Study of enterovirus replication in human tissue explants, using photosensitized virus strains.


Study of the oxygen effect mediated by Janus green B.


Subcellular distribution of oxidative enzymes in human, inflamed and dilantin hyperplastic gingiva.


Subcellular localization of ribonucleotide reductase in Novikoff hepatoma and regenerating rat liver.


Subclinical congenital cytomegalovirus infection and hearing impairment.


Subcutaneous adipose tissue and lipids in blood in growth hormone deficiency before and after treatment with human growth hormone.


Succinate dehydrogenase and cytochrome oxidase in adult and plerocercoid Diphyllobothrium latum.


Substrate activation and product inhibition of LDH activity in human skeletal muscle.


Suppression of fibrinolysin T activity fails to restore density-dependent growth inhibition to SV3T3 cells.


Surgery of the pterygoid fossa.

Surgery of the pterygoid fossa.


Survival and growth in a woman with untreated hypothalamic panhypopituitarism of 21 years' duration. A 29-year-old woman with evidence of a craniopharyngioma and documented panhypopituitarism is described. Clinical and laboratory evaluation revealed deficiencies of follicle-stimulating hormone, luteinizing hormone, thyroid-stimulating hormone, growth hormone, prolactin, adrenocorticotropic hormone and antidiuretic hormone. Prompt release of several pituitary hormones was noticed after administration of the hypothalamic releasing hormones FSH/LH-RF and thyrotropin-releasing hormone, whereas insulin-induced hypoglycemia, levodopa, chlorpromazine and clomiphene citrate, all of which act at the level of the hypothalamus, did not alter basal pituitary secretion. The patient's height of 60 inches, despite panhypopituitarism, and the interpretation of the above data are discussed in the light of current concepts regarding the dynamics of the hypothalamic-hypophyseal system.


Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazoles.


Synthesis and antimicrobial activity of aliphatic nitro compounds.


Synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3.


Synthesis and secretion of plasma lipoproteins.


Synthesis of diphosphoinositide by a soluble fraction of Saccharomyces cerevisiae.


Synthesis of viral mRNA and polyadenylate by a ribonucleoprotein complex from extracts of VSV-infected cells.


Sympathetic-parasympathetic interactions on the ventricular myocardium: possible role of cyclic nucleotides.


Synthesis of 1-(3-deoxy-beta-D-psicofuranosyl)uracil and related compounds. D-Fructose affords on treatment with cyanamide 2-amino-beta-D-fructofuro[2',3':3,4]-oxazoline which is not isolated but transformed directly by the reaction with ethyl propiolate into O(2,3)-anhydro-2-[beta-D-fructofuranosyl]uracil. This compound is benzoylated to the 1',4',6'-tri-O-benzoyl derivative by the action of benzoyl cyanide and triethylamine. On treatment with hydrogen chloride/dimethylformamide, the latter intermediate is converted to the 1-[1,4,6-tri-O-benzoyl-3-chloro-3-deoxy-beta-D-psicofuranosyl]uracil 1',4',5'-tribenzoate from which the title nucleoside derivative is obtained by methanolysis.


Temperature effects on the concanavalin A molecule and on concanavalin A binding.


Test and teach number two.

Test and teach number two.


Testing of antiviral compounds against Mengo virus infection of mice. I. Screening of compounds and statistical evaluation of their effects.


The absorption of conjugated oestrogen and sodium oestrone sulphate from the vagina.


The action of phospholipase C and lipase on black film bilayer membranes.


The adhesion of BHK and PyBHK cells to the substratum.


The apolipoproteins.

The apolipoproteins.


The archaic barbiturate hypnotics.

The archaic barbiturate hypnotics.


The binding of reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase to hepatic microsomes.


The changing attitudes of women: implications for psychotherapy.


The carbohydrate moiety of sea cucumber (Thyone briareus) gelatin.


The clinical and chemical heterogeneity of the beta-thalassemias.


The clinical-chemical application of the NADH test for the determination of diamine oxidase activity in human pregnancy.


The denervated heart. A model for studying autonomic control of the heart.


The degradation of ribonucleic acids injected into Xenopus laevis oocytes.


The detection of hyaluronidase on electrophoresis membranes.


The development of nerve-muscle junctions in Rana catesbeiana tadpoles.


The effect of cyclic 3',5'-adenosine monophosphate on yeast glyceraldehyde-3-phosphate dehydrogenase. II. Initial velocity kinetic studies.


The effect of alpha-tocopherol on cerium induced changes in drug and lipid metabolism of rat.


The effect of glucagon on adenosine 3',5'-monophosphate (cyclic AMP), glucose, insulin and growth hormone in the full term newborn and children.


The effect of population density on phenylalanine hydroxylase activity in rat-hepatoma cells in culture.


The effect of orally administered cocaine on sleep of depressed patients.


The effect of prior inoculation with an enterovirus (LEV 4) on rhinovirus infection of volunteers.


The effect of pH on hycanthone methanesulfonate-induced inactivation and mitotic recombination in saccharomyces.


The effect of synthetic corticotropin analogues on adrenocortical, anterior pituitary and testicular function.