Preliminary studies on rat olfactory tissue: effects of odorants on NA+-K+ atpase activity.


The role of cyclic AMP in slime mold development.


Reactivity of artificial substrates for prenyltransferase.


Kinetic properties of phosphoribosyladenosine triphosphate synthetase. Inhibition by aggregation at high enzyme concentrations.


Chloramines as intermediates of oxidation reaction of amino acids by myeloperoxidase.


A K+-activated, ethacrynic acid-sensitive p-nitrophenylphosphatase from normal human white cells.


Cyclic 3',5'-AMP phosphodiesterase of Saccharomyces carlsbergensis. Inhibition by adenosine 5'-triphosphate, inorganic pyrophosphate and inorganic polyphosphate.


Angiotensin-converting enzyme from porcine plasma.


The effect of halothane on mitochondrial permeability to NADH.


Studies on the glucocorticoid feedback control of ACTH secretion.


Intermediary metabolism in the liver and adipose tissue of rats with hormone-secreting pituitary tumors.


Modification of the kinetics and regulatory properties of bovine hepatic fructose 1,6-diphosphatase with pyridoxal 5'-phosphate.


Several topics concerning Na,K-ATPase.

Several topics concerning Na,K-ATPase.


Sensitized guinea-pig lung: altered adenylate cyclase stimulation by epinephrine.


Histamine H2 receptors and cyclic AMP in brain.


Effects of methyl xanthine derivatives on cyclic AMP levels and ornithine decarboxylase activity of rat tissues.


Opiate receptor phenomenon: proconvulsant action of morphine in the mouse.


Constrictive pericarditis following acute Coxsackie viral pericarditis.


Lingual thyroid scanned with technetium 99m pertechnetate. Report of two cases.


Parainfluenza virus immunization. IV. Simultaneous immunization with parainfluenza types 1, 2, and 3 aqueous vaccines.


Fatal pneumonia associated with adenovirus type 7.


Nemaline myopathy. A fatal case.

Nemaline myopathy. A fatal case.


Studies of the immunogenicity, communicability and genetic stability of oral poliovaccine administered during the winter.


Cytomegalovirus infection among migrant children.


A protective mechanism induced by live group B arboviruses against heterologous group B arboviruses independent of serum neutralizing antibodies or interferon.


Vesicular stomatitis virus, Indiana type: an arbovirus infection of tropical sandflies and humans?


Delirium tremens and dreaming.

Delirium tremens and dreaming.


Vesicular stomatitis virus in Panama. Human serologic patterns in a cattle raising area.


Rhinovirus infections in hospitalized children. Provocative bacterial interrelationships.


Pulmonary effects of sulfur dioxide exposure in the Syrian hamster. I. Combined with viral respiratory disease.


Wilson's disease. Report of patient with osseous manifestations.


Microphotometric determination of DNA and RNA in single chick embryo fibroblasts during morphological transformation induced by Rous sarcoma virus.


Separation of blood cells using colloidal silica-polysaccharide gradients.


Electron microscopy of the hepatocellular and Kupffer-cell lesions of mouse hepatitis, with particular reference to the effect of cortisone.


Vitiligo and sympathectomy. The effect of sympathectomy and alpha- melanocyte stimulating hormone.


Oxyphil adenoma four years after a benign mixed tumor.


The roentgen features of synovial sarcomas.


Sleeping patterns in female guinea pigs; effects of sex hormones.


Reserpine and corticotrophin secretion.

Reserpine and corticotrophin secretion.


Steroid excretion and plasma cortisol in 41 cases of Cushing's syndrome. With data on corticotrophin and metapyron tests.


Cytomegalovirus in the normal pregnant woman.


Tissue culture study of abnormal trophoblast. Growth pattern and nuclear sex.


Oxidized and reduced forms of nicotinamide nucleotides in livers of tuberculous mice.


Roentgenographic appearance of bronchogenic adenocarcinoma.


The etiology of acute upper respiratory disease in a college student population.


Provocative tests of growth-hormone release. A comparison of results with seven stimuli.


Membranous glomerulonephritis: virus-like inclusions in glomerular basement membrane.


Cushing's syndrome with dual pituitary-adrenal control.


Diagnosis and treatment of beta-adrenergic receptor hyperresponsiveness. A critical appraisal.


Live and inactivated adenovirus vaccines. Clinical evaluation of efficacy in prevention of acute respiratory disease.


Studies in ageing of the brain. I. Isolation and preliminary characterization of Alzheimer plaques and cores.


Psychiatric symptoms masking an insulinoma (a case report).


Metabolism of fatty acids in the rat adrenal gland.


Melanin-dispersing effect of adenosine 3',5'-monophosphate on amphibian melanophores.


Relation of the adrenal and pituitary to the hypocholesterolemic effect of estrogen in rats.


The inhibition of chick embryo cell growth by medium obtained from cultures of Rous sarcoma cells.


Relative depletion of an arginine-rich deoxyribonucleo-histone component during tumor induction by the Shope papilloma virus.


The separation of haemagglutination inhibitors from antibodies to parainfluenza viruses by gel filtration on a Sephadex G-200 column.


Tenacity of porcine Graafian follicle as it approaches ovulation.


Salivary gland enlargement in rats after administration of theophylline.


Some characteristics of Machupo virus, causative agent of Bolivian hemorrhagic fever.


The isolation of Ilhéus virus from man in Panamá.


Sleep paralysis and hypnagogic hallucinations. Their relationship to the nightmare.


RNA tumour virus. Leukosis agent.

RNA tumour virus. Leukosis agent.


Adult heart disease due to the Coxsackie virus group B.


The hand as a sign-post to ocular disease--I.


Cystosarcoma phylloides.

Cystosarcoma phylloides.


Effect of viruses on early mammalian development. III. Further studies concerning the interaction of Mengo encephalitis virus with mouse ova.


Cross talk--the paradoxical transmission of a nerve impulse.


Granular-cell myoblastoma of the anterior uvea.


Genital herpesvirus infection. Diagnosis and significance.


Metabolic effects of hydroxyurea on BHK-21 cells transformed with polyoma virus.


The influence of sodium diethyldithiocarbamate on behavior and EEG in cats and rabbits.


Topical treatment of cutaneous herpes simplex in humans with the non-steroid antiinflammatory drugs: mefenamic acid and indomethacin in dimethylsulfoxide.


Beta-galactosidase activity of Saccharomyces fragilis. II. Mode of action.


Adenovirus type 7 outbreak in a kindergarten.


Polypeptide receptor mechanisms.

Polypeptide receptor mechanisms.


Cardiovascular reactivity in acute and chronic renal hypertensive dogs.


Indirect estimation of safety margin in neuromuscular transmission.


Observations on concealed conduction in atrial fibrillation.


Alteration in vasoactive polypeptide receptor activity of rat fundal strip by heat and urea.


Physiological differences between the effects of neuronally released and bloodborne norepinephrine on beta adrenergic receptors in the arterial bed of the dog.


Infectious bronchitis in laying fowls.

Infectious bronchitis in laying fowls.


Submaxillary gland blood flow: the role of kinins and beta-adrenergic receptors.


Mediator of vasodilatation in the submaxillary gland.


An evaluation of estrogenic substances in the treatment of cerebral vascular disease. Report of the Veterans Administration Cooperative Study of Atherosclerosis, Neurology Section.


Juvenile nasopharyngeal angiofibroma.

Juvenile nasopharyngeal angiofibroma.


Post-irradiation mesenchymal chondrosarcoma. A case report.


Congenital mesoblastic nephroma of infancy. A report of eight cases and the relationship to Wilms' tumor.


Glucose-6-phosphate content in mammalian pancreatic beta-cells. Effects of various stimulators and inhibitors of insulin release.


Adrenocortical stimulation tests with ACTH: developments and changes of a diagnostic procedure.


Cytomegalovirus syndrome in children with acute leukemia. Treatment with floxuridine.


Rapid intravenous administration of corticotropin as a test of adrenocortical insufficiency.


The Lasègue test.

The Lasègue test.


Metabolic and pathologic investigation of 1-aminocyclohexanecarboxylic acid (ACHC), a metabolite of 6-(1-aminocyclohexanecarboxamido)-penicillanic acid (cyclacillin).


Studies on the effects of anticonvulsant drugs on the activity of vitamin D in rats and dogs.


Suppression of activities of carbohydrate-metabolizing enzymes in adipose tissue of obese humans by clofibrate.


5-Hdroxytryptamine in platelets and 5-hydroxyindole-acetic acid in urine in asthma and other diseases of the respiratory tract.


Electrical responses in crus I evoked by stimulating various parts of the cat cerebellar vermis.


Projections of the inferior colliculus in the monkey.


The anticonvulsant activity of triethylcholine in cats.


Pavlovian theory of dreaming.

Pavlovian theory of dreaming.


The rate of regeneration of the vagus nerve of the cat.


The importance of the convulsion in occurrence and rate of development of electroconvulsive threshold elevation.


Fiber degeneration following lesions in the anterior ventral cochlear nucleus of the cat.


The fiber component of the midcervical vagus nerve implicated in vagotomy-induced lung edema.


Incorporation of C-14 lysine into spinal roots, spinal ganglia and peripheral nerves of the rat.


Monosynaptic transmission from afferents of one segment to motoneurons of other segments in the spinal cord.


Computer determination of relationships between EEG activity and single unit discharges in isolated cerebral cortex.


Potassium depletion in patients with chronic respiratory failure.


Clinical and physiological follow-up of severe chronic obstructive lung disease. Case reports are given of 25 patients with severe chronic obstructive lung disease (COLD) and with a ventilatory capacity (MVVF) < or = 35 per cent of predicted normal values. The patients were selected among persons treated 1968-1970 at the Department of Pulmonary Diseases, University Hospital, Uppsala. Clinical and physiological follow-up studies have been made. Case histories, physical and radiological findings of the heart and lungs and in 5 patients autopsy findings are given. Arterial blood gas tensions and acid-base balance in the patients' habitual state are also reported. Changes in the electrocardiograms (ECG), in lung volumes and dynamic ventilatory function and physical working capacity, measured on a bicycle ergometer, are described. In 1970-71 the patients (39-72 years of age) were admitted to hospital for 5 days in their optimal state for the following investigations: static and dynamic spirometry, total haemoglobin, ECG, vectorcardiogram (VCG), physical working capacity, pulmonary gas exchange and central haemodynamic studies. The results of the gas exchange and central haemodynamic studies, total haemoglobin and the physical working capacity are given elsewhere. Certain comparisons were made between the two groups of patients: (R) patients who had had one or several periods of manifest respiratory insufficiency with intensive treatment (n = 14) and a comparison (C) group (n = 11), with the same ventilatory impairment in regard to MVVF, but without any corresponding periods needing oxygen treatment combined with breathing assistance by a physiotherapist or respirator. Sixteen patients had chronic bronchitis with emphysema, one chronic bronchitis without emphysema, four primary emphysema, one emphysema and bronchial asthma and three emphysema and widespread bronchiectasis. The most striking difference in the clinical history of the R-and C-group patients was a greater tobacco consumption (packets/lifetime) in the R group. The ECG was typical for right ventricular hypertrophy (RVH) in one patient from each group. Slightly delayed ventricular activation and clock-wise rotation of the QRS frontal plane axis were the most common ECG findings. VCG was typical for RVH in one C-group and 4 R-group patients, and suspected to indicate RVH in 7 R- and 5 C-group patients. Biventricular hypertrophy may be one of the reasons that ECG and VCG do not more often fulfil the typical RVH criteria. The average MVVF was about 21 per cent of predicted normal values before and about 27 per cent after administration of a bronchodilating spray. The average vital capacity (VC) was 55 per cent before and 64 per cent after the use of a spray.(ABSTRACT TRUNCATED AT 400 WORDS)


Unusual uterine perforation with a new intrauterine device.


Rapid pregnancy urinary estrogen assays. A comparative study.


Mesonephroid tumors of the ovary. Clinical and histopathologic studies.


Gonadal dysgenesis with ovarian function. Clinical and cytogenetic findings in six patients.


Psychogenic polydipsia causing acute water intoxication in pregnancy at term. A case report.


Passage of inulin from gravida to fetus in normal pregnancy and during cesarean section.


Neonatal effects of maternal treatment with the anticonvulsant drug diphenylhydantoin.


Catecholamine response to radical pelvic operation.


Prognostic factors in epidermoid carcinoma of the vulva.


Fetal deprivation and placental insufficiency.


Serial sella turcica X-ray studies in women taking oral contraceptives.


Prenatal sex determination. Detection of "Y body".


The wing sound. A new uterine measuring device.


Flexible arm support for the laparoscope.


Placentation and mammalian phylogeny.

Placentation and mammalian phylogeny.


Vaginal deodorants.

Vaginal deodorants.


Neonatal methemoglobinemia following epidural anesthesia.


Prolonged pregnancy.

Prolonged pregnancy.


Acute otitis media in children. Serologic studies and attempts to isolate viruses and mycoplasmas from aspirated middle-ear fluids.


Diet and infrequent peritoneal dialysis in chronic anuric uremia.


Predicting prescription prices.

Predicting prescription prices.


Amyloidosis (concluded).

Amyloidosis (concluded).


Toxic psychosis from sleeping medicines containing scopolamine.


Polydipsia associated with occult hydrocephalus.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1967. Pulmonary cavities after transthoracic ligation of esophageal varices.


Cleverness of the kidneys.

Cleverness of the kidneys.


The drug wars.

The drug wars.


Intestinal adhesions.

Intestinal adhesions.


Doctors' dining clubs.

Doctors' dining clubs.


The breast-cancer group.

The breast-cancer group.


Balint's syndrome.

Balint's syndrome.


Definition of progestogens.

Definition of progestogens.


Bird-headed dwarfs.

Bird-headed dwarfs.


Hazards of mycophagy.

Hazards of mycophagy.


Blood volume and pulse pressure.

Blood volume and pulse pressure.


Conjugation of bilirubin.

Conjugation of bilirubin.


Colonic injury from hydrogen peroxide.

Colonic injury from hydrogen peroxide.


Anosmia in eunuchoidism.

Anosmia in eunuchoidism.


Prognosis after surgical treatment of granulomatous colitis.


Units of sodium heparin.

Units of sodium heparin.


Seckel's bird-headed dwarfism.

Seckel's bird-headed dwarfism.


Chondrocalcinosis of the knee with gout and rheumatoid arthritis.


Segmental stenosis of saphenous-vein autografts. Preventable cause of late occlusion in arterial reconstruction.


Carcinoma of the breast. A decade of new results with old concepts.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-1967. Rheumatoid arthritis, Felty's syndrome and uremia.


The sense of smell in man--its physiologic basis.


Granulomatous colitis.

Granulomatous colitis.


Satellites and forces.

Satellites and forces.


Abdominal bruits.

Abdominal bruits.


Cancer of the breast.

Cancer of the breast.


Disease vs. nondisease of the heart.

Disease vs. nondisease of the heart.


Hypernatremia during sodium sulfate therapy.


Pathways of fat embolism.

Pathways of fat embolism.


Educating the perceptive specialist.

Educating the perceptive specialist.


Mitochondrial ATP synthesis.

Mitochondrial ATP synthesis.


Pulmonary embolism and blood flow.

Pulmonary embolism and blood flow.


Untoward effect of diazepam.

Untoward effect of diazepam.


Inadequacy of multiple-choice examinations.


Isovaleric acidemia. Clinical features of a new genetic defect of leucine metabolism.


Hepatic-artery ligation for hepatic hemangiomatosis.


Bile-salt deficiency in the steatorrhea following resection of the ileum and proximal colon.


Porphyria precipitated by fasting.

Porphyria precipitated by fasting.


Disorders of sexual development.

Disorders of sexual development.


Perception of isovaleric acidemia.

Perception of isovaleric acidemia.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 34-1967. Death eighteen days after vena-cava ligation for recurrent pulmonary embolism.


Treatment of hemangiomatosis by hepatic-artery ligation.


Are teachers born?

Are teachers born?


Medical pedagogy.

Medical pedagogy.


"Ruptured abdominal aneurysm".

"Ruptured abdominal aneurysm".


Effect of phenobarbital on jaundice.

Effect of phenobarbital on jaundice.


Management of occluded renal artery.

Management of occluded renal artery.


Sugary correction.

Sugary correction.


The case for mumps vaccine.

The case for mumps vaccine.


Antibiotic treatment of endocarditis.

Antibiotic treatment of endocarditis.


Vascular infundibula vs. diverticula.

Vascular infundibula vs. diverticula.


Mental health and suicide.

Mental health and suicide.


Dihydrotachysterol content of "hytakerol".


Physicians' feelings.

Physicians' feelings.


Archaeologist M.D.

Archaeologist M.D.


Representation without taxation.

Representation without taxation.


Unified support for therapeutic goals.

Unified support for therapeutic goals.


Early reduction of pulmonary vascular resistance after mitral-valve replacement.


"Undisgruntled AFCR".

"Undisgruntled AFCR".


Impaired epinephrine release in hypoglycemic infants of diabetic mothers.


Studies of testosterone metabolism in a patient with masculinization due to stromal hyperthecosis.


Ophthalmic manifestations of the carcinoid flush.


The rights of patients.

The rights of patients.


Mechanism of digitalis action on the heart.


Recurrent renovascular hypertension.

Recurrent renovascular hypertension.


Reversible pseudo-Pelger anomaly related to sulfisoxazole therapy.


Pulmonary vascular disease in mitral stenosis.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1967. Sudden headache and vertigo in a man with hypertension.


Control of the synthesis and secretion of epinephrine.


National boards and state discretion.

National boards and state discretion.


Cannula sepsis.

Cannula sepsis.


Variable reactions to stress.

Variable reactions to stress.


Adenoid basal lesions of the cervix.

Adenoid basal lesions of the cervix.


Ultrastructure of an interstitial (hilar) cell tumor of the ovary.


Primary ovarian sarcomas. Report of 43 cases from the Emil Novak Ovarian Tumor Registry.


Spinal-fluid pH and neurologic symptoms in systemic acidosis.


Radioimmunoassays of peptide hormones in plasma.


Electrodiagnosis.

Electrodiagnosis.


Natural history of uremic polyneuropathy and effects of dialysis.


Uremic neuropathy.

Uremic neuropathy.


Observations and comments on failure of dexamethasone suppression.


Reliability and significance of the dexamethasone suppression test in Cushing's disease.


Oral contraceptives--50 million users.

Oral contraceptives--50 million users.


A prospective study in general practice on breast-cancer risk in postmenopausal women.


Death from bowel obstruction due to intragastrically administered kaolin.


Advanced bio-electronics the value of the RKG 100 radio-cardiogram in industry.


A successful management of the peptic ulcer patient in industry.


Participation of the central nervous system in decompression.


Compensation for hearing loss.

Compensation for hearing loss.


Rates and costs of occupational accidents in Egypt.


Accidents by venomous animals in Colombia.


Interpretation of injury from the standpoint of labor.


The development of a voluntary periodic health program in industry.


Otogenic vertigo--an occupational hazard.


Fetal blood typing after induced abortion.


Representation of the ABH blood group system in the dog.


About increase of aggregation of red cells with an increase of temperature in normal and abnormal blood (i.e. cancer). Effect of ABO blood groups and proteins.


Clinical and experimental projects on chemotherapy of bladder tumours.


Cholesterol in mycoplasma membranes. II. Components of Acholeplasma laidlawii cell membranes responsible for cholesterol binding.


Isolation, solubilization, and reconstitution of mycoplasma membranes.


Diuretic action of triamterene in man.

Diuretic action of triamterene in man.


The detection of asymptomatic bacteriuria in general practice.


Behaviour therapy in relation to contemporary psychotherapy.


Epidemiology and the general practitioner.


Anthrax. Biological and immunological principles of diagnosis and prevention. 6. The effect of specific treatment on the diagnosis of anthrax using anthraxin.


The social context of first marijuana use.


Preoperative hormonal therapy of cystic adnexal masses.


Arbovirus infections of sentinel cattle in Australia and New Guinea.


Binding of water to "types I and II" Cu2+ in proteins.


Studies on ubiquinone. Demonstration of the total biosynthesis of ubiquinone-9 in rat liver mitochondria.


The importance of type IV hyperlipoproteinemia as a predisposing factor in coronary artery disease.


Extractions on medical grounds.

Extractions on medical grounds.


Medical management of chronic renal failure.


Nature of the inhibitors of lactate dehydrogenase in uremic dialysates.


Disappearance of tumors induced by adenovirus type 12 after differential hypothermia treatment.


Protein binding of diphenylhydantoin and desmethylimipramine in plasma from patients with poor renal function.


Effects on rat kidney slice function in vitro of proteins from the urines of patients with myelomatosis and nephrosis.


Direct evidence for Hageman factor (factor XII) activation by bacterial lipopolysaccharides (endotoxins). Purified precursor Hageman factor has been demonstrated to bind to soluble bacterial lipopolysaccharide (LPS, endotoxin) isolated from Escherichia coli 0111:B4, and this complex has been shown to have the capacity to convert prekallikrein to its active form. In addition, LPS-activated Hageman factor substantially reduces clotting times in XII-deficient plasma. The capacity to activate Hageman factor has been demonstrated to reside in the lipid A region of the LPS molecule. Activation of Hageman factor by LPS contrasts with fluid-phase activation (e.g., by kallikrein or trypsin) in that no cleavage to lower molecular weight fragments occurs. High concentrations of LPS inhibit the activity of Hageman factor, probably by a direct LPS-Hageman factor interaction.


Editorial: The Delaney Clause.

Editorial: The Delaney Clause.


Clotting factor deficiencies in rats fed a modified iodine-deficient diet.


DDE, PTH and eggshell thinning in mallard, pheasant and ring dove.


Effects of 15 common environmental pollutants on eggshell thickness in mallards and coturnix.


The effect of DDT and PCB on lipid metabolism in E. coli and B. fragilis.


Removal by DTPA of internally deposited Am: a comparative study on rats and Syrian hamsters.


Factors involved in increased protein synthesis in rat kidney after administration of DDT.


Cholinoceptive sites in the ganglia of myenteric plexus subserving the peristaltic reflex of guinea-pig isolated ileum.


Catalytic method for determination of iron in blood serum.


A haematocrit corrected micro determination of the P&P-test and blood clotting factors in capillary blood.


DDT induced chromosome mutations in mice--further testing.


Comparative rates of spontaneous mutation.


Does a pheromone-like factor from the nestling rabbit stimulate impregnation and maturation in the rabbit flea?


Formation of slow-reacting substance of anaphylaxis in human lung tissue and cells before release. The capacity to extract slow-reacting substance of anaphylaxis (SRS-A) from human lung tissue or cells after immunologic activation, together with the measurement of SRS-A in both the extract and the surrounding fluid, permits study of total SRS-A generation. That the material extracted is SRS-A was established by both differential bioassay and purification. SRS-A accumulation was entirely intracellular after limited IgE-dependent direct or reversed anaphylactic activation. Intracellular accumulation also generally preceded release, with generation of SRS-A continuing well beyond a plateau in the cellular SRS-A level and the release of preformed mediators. The quantity of SRS-A generated after immunologic activation was modulated by the introduction of exogenous cyclic nucleotides, revealing a site of cyclic nucleotide action distinct from that on mediator release. The capacity to determine not only the release of preformed mediators but also the generation of a newly formed mediator, the sum of SRS-A in cells and supernate, adds an additional dimension to the analysis of the cellular events of immediate hypersensitivity.


On the molecular basis of pyruvate kinase deficiency.


Childhood interest clusters related to creativity in women.


Residual effects of brain damage and five MMPI items.


Age, intelligence, and MMPI F scores.

Age, intelligence, and MMPI F scores.


Drug agranulocytosis. A case study.

Drug agranulocytosis. A case study.


Anticholinergic drugs in the management of duodenal ulcer.


A therapeutic trial of prolintane.

A therapeutic trial of prolintane.


Gout and diabetes; report of a case with severe diabetes and polyarthritic non-tophaceous gout.


Diagnostic screening tests in mental retardation.


The maternal instinct in cancer control.


Carbon monoxide poisoning.

Carbon monoxide poisoning.


"Estergel"--a new topical vehicle.

"Estergel"--a new topical vehicle.


The liver and infectious mononucleosis.

The liver and infectious mononucleosis.


Malingering.

Malingering.


A clinical study of fecal pH in pediatric constipation.


Antibiotics in 1965.

Antibiotics in 1965.


Compression therapy in ulcers of necrobiosis lipodica diabeticorum.


A study of a group of dental students, including their diet and dental health.


The epidemiology and treatment of strokes in Lake County, Illinois.


Actions of certain drugs injected into the ventricular system of man (intraventricular endephalo-pharmaco-therapy).


Reduced pyridine coenzymes as hydrogen donors in repair of radiation damage.


A report of Dirofilaria immitis in Sorsogon Province, Philippines.


Monoamine oxidase in mammalian blood platelets.


Economic behaviour under uncertainty.

Economic behaviour under uncertainty.


Diurnal variation in urinary excretion of calcium and strontium.


Evidence for the presence of DNA at basal body sites in  Tetrahymena pyriformis.


Organ-weights and body-composition in mice bred for many generations at -3 degrees C.


Extracellular products of phytoplankton photosynthesis.


The role of calcium in the increase in flocculence of yeast growing in the presence of copper.


Aegialodon dawsoni, a new trituberculosectorial tooth from the Lower Wealden.


Relapse and non-relapse in alcoholic patients.


Relationships between response to the Marlowe-Crowne Social Desirability Scale and MMPI scales.


Use of actuarial description of abnormal personality in a mental hospital.


Coping and defense mechanisms related to personality inventories.


Age changes in the effects of ordinal position on sex-role identification.


Association responses of depressed and non-depressed patients to words of three hostility levels.


Ipechar--a poison control kit.

Ipechar--a poison control kit.


Transseptal orchidopexy.

Transseptal orchidopexy.


Acute massive gangrene of tongue.

Acute massive gangrene of tongue.


Immunization against whooping-cough.

Immunization against whooping-cough.


Contributions of blood groups to human genetics.


Molecular transport at cell membranes.

Molecular transport at cell membranes.


Further studies on the kinetics and equilibria of the reaction of nitric oxide with haemoproteins.


Rates of reaction of Ascaris haemoglobins with ligands.


Transient changes in isotonic shortening velocity of frog rectus abdominis muscles in potassium contracture.


The maintenance energy of bacteria in growing cultures.


Breeding habits of Windermere charr, Salvelinus willughbii (Günther), and their bearing on speciation of these fish.


The incidence of undescended testis in boys attending elementary schools in Greece.


Management of causes of vaginal discharge (especially trichomoniasis and mycosis).


Mental retardation in methemoglobinemia due to diaphorase deficiency.


A blind study of enamel opacities and dental caries prevalence after eight years of fluoridation of water.


The spermatogram of hormone-treated patients and of surgical-treated patients with maldescended testicle.


Manifest aggression: MMPI correlates in normal boys.


Acquiescence, hypnotic susceptibility, and the MMPI.


Host-parasite relationships of some Thelohania from mosquioes (Nosematidae: Microsporidia).


The technology of teaching.

The technology of teaching.


Maternal performance in mice at -3 degrees C: food consumption and fertility.


The effect of sugar solutions on pH of dental plaques from caries-susceptible and caries-free individuals.


A statistical confidence interval for true per cent reduction in caries-incidence studies.


Properties of a new TPN-like electron transport component from Mycobacterium phlei.


A relationship between adrenaline and the mode of action of oxytocin and oestrogen on vascular smooth muscle.


Synergistic action of an anti-5-hydroxytryptamine, anti-histamines and cortisone in experimental anaphylaxis.


Complications of smallpox vaccination.

Complications of smallpox vaccination.


Central cholinergie blockade of the conditioned avoidance response in rats.


Alpha-hydroxy acid oxidase: localization in renal microbodies. Differential and density equilibrium centrifugation have established the presence of alpha-hydroxy acid oxidase in microbodies of the kidney of the rat. The enzyme has been demonstrated in cells of the distal convoluted tubule by a microscopic cytochemical method. This enzyme, like certain others in microbodies, produces hydrogen peroxide.


A new respiratory stimulant.

A new respiratory stimulant.


Influence of the sympathetic nervous system on the response of the normal heart to digitalis.


Transperitoneal exposure in cryptorchism.


Personality variables and attitudes toward traditional cultural fantasy.


A test of the relationship between repressed homosexuality and paranoid mechanisms.


Differential MMPI performance of brain-damaged vs. pseudo-neurologic groups.


The influence of religious affiliation on the MMPI scales.


Personality characteristics of three disability groups.


Set and content scores for personality scales and response styles in the MMPI.


Comments on the international conference on the prevention of malnutrition in the pre-school child.


Dengue hemorrhagic fever in South Vietnam: report of the 1963 outbreak.


The maintenance of a life support atmosphere in sealed systems.


Mosquito ecology in central Alberta. I. The environment, the species, and studies of the larvae.


Tetrahydroaminacrine in anaesthesia.

Tetrahydroaminacrine in anaesthesia.


Susceptibility of pneumococci to nine antibiotics.


Use of doxapram hydrochloride to restore respiration in anesthetized man.


Imperfectly descended testicle. A review.


Relationships among ego strength measures.


Comparison of normalized and linear T scores in the MMPI.


Pathways of oxidation of reduced nicotinamide nucleotides in the central nervous system of marine animals.


Effects of stimulants of the central nervous system on the pyridoxal phosphate content of the rat brain.


Inhibition of acute effects of hydralazine by an adrenergic beta-receptor blocking agent.


Streptococcal red-cell-sensitizing antigens.


Necrotizing angiitis. II. Findings at autopsy in twenty-seven cases.


Electroencephalographic studies on the action of monoamine oxidase inhibitor.


On the mechanism of the adrenal gland response to adrenocorticotrophic hormone in hypophysectomized rats.


The effects of pipradrol hydrochloride and sodium amylobarbitone on operant responding in a discrimination situation.


A new test for morphine-like physical dependence (addiction liability) in rats.


Antagonism to reserpine induced depression by imipramine, related psychoactive drugs, and some autonomic agents.


Pharmacological and toxicological properties of two new beta-adrenergic receptor antagonists.


Cardiovascular pharmacology of two new beta-adrenergic receptor antagonists.


Effect of hemicholinium on the catecholamine depleting actions of reserpine, morphine and insulin in rabbit tissues.


Free amino acids and related compounds in brain and other tissues: effects of convulsant drugs.


Mechanism for nicotine and DMPP on the isolated rat atria-vagus nerve preparation.


The 1965 Congressional inquiry into testing: a commentary.


Testimony before the Senate Subcommittee on Constitutional Rights of the Committee on the Judiciary. June 7-10, 1965, Washington, D. C.


The flight activity of some East African mosquitos (Diptera, Culicidae). I. Studies on a high steel tower in Zika Forest, Uganda.


Nucleus and cell membrane conductance in marine oocytes.


Antihistamines.

Antihistamines.


Brain amines and electroshock convulsive threshold.


The electrical and contractile activity of the pyloric region in dogs and the effects of drugs.


The effects of stimulant and tranquilizer placebos on healthy subjects in a real-life situation.


Butaperazine and prochlorperazine; a comparative trial of two phenothiazines.


Ganglionic blocking action of piperidino-methyl-khellin.


Mental health--march to excellence.

Mental health--march to excellence.


Adult neurology--1965.

Adult neurology--1965.


The teen-ager.

The teen-ager.


Management of marital problems.

Management of marital problems.


Follow-up of the discharged mental patient--a discussion.


The synthesis of pyridine nucleotides in fresh and stored human erythrocytes.


Follow-up of the discharged mental patient.


Childhood seizures resistant to conventional medications.


Who treats the burned child?

Who treats the burned child?


Management of upper respiratory disorders with a liquid sustained-release antihistamine.


Nursing home placement: the physician's role.


Traumatic injuries of the pancreas and the management of traumatic pancreatic pseudocysts.


Recent advances in reproductive endocrinology.


Aneurysm of the common hepatic artery.

Aneurysm of the common hepatic artery.


Compound 84/F 1983 compared with D-amphetamine and placebo in regard to effects on human performance.


Clinical studies with clorprenaline, a new bronchodilator with and without the antihistamine methapyrilene.


Nicotinamide coenzyme concentrations in mammary biopsy samples from ketotic cows.


Residual psychopathology in released psychiatric patients and its relation to readmission.


Chemical studies in relation to convulsive conditions. Effect of Telodrin on the liberation and utilization of ammonia in rat brain.


Glucuronic acid research in Japan.

Glucuronic acid research in Japan.


Conversion of immunological paralysis to immunity by endotoxin.


Adrenergic alpha- and beta-receptors in the mouse iris.


School fluoridation studies in Elk Lake, Pennsylvania, and Pike County, Kentucky: interim report.


Drug intoxication.

Drug intoxication.


Social desirability and order of item presentation in the MMPI.


Anticholinesterase activity of tetrahydroaminacrine and succinyl choline hydrolysis.


Nucleoside diphosphate sugars and saccharide synthesis.


The inhibition of 3-alpha-hydroxy steroid-activated nicotinamide-adenine dinucleotide (phosphate) transhydrogenase by some antimetabolic compounds.


Action spectra and quantum yields for nicotinamide--adenine dinucleotide phosphate reduction by chloroplasts.


Johnson or Goldwater?: some personality and attitude correlates of political choice.


Induction of alkaline phosphatase in a subcellular preparation from Escherichia coli.


The role of Banthine in general dentistry.


The oxidation of citrate, isocitrate and cis-aconitate by isolated mitochondria.


Selected dental findings: a challenge to the American dentist.


Retention of energy transfer in glycerinated chloroplasts.


Phenylisopropylmethylpropinylamine (E-250), a new spectrum psychic energizer.


Personality correlates of the degree of functional incapacity of patients with physical disease.


Some pharmacologic characteristics of a new antihistaminic (SQ 10,648), 11-(2-dimethylaminoethyl)-6,11-dihydrodibenz-[b,e] [1,4] oxazepine maleate.


The transformation of glyceryl trinitrate and other nitrates by glutathione-organic nitrate reductase.


Secretin inhibition of gastric hydrochloric acid in human beings.


A constant-temperature mosquito-rearing apparatus.


Clinical use of sodium nafcillin in pediatric practice.


Necrotizing arteritis with giant cells associated with haemolytic anaemia. Necrotizing arteritis with giant cells, involving the aorta, pulmonary and coronary arteries, and coronary, splenic, and renal arterioles was found at necropsy in a 74-year-old male who had died with severe haemolytic anaemia associated with cold haemagglutinins. The clinical and pathological features of this case are shared by well-recognized forms of necrotizing angiitis, in particular giant cell arteritis, but do not conform satisfactorily with any of these disorders. Cold agglutinin haemolytic anaemia in this instance suggests the possibility of an autoimmune aetiology.


A higher parotid fluid flow rate in subjects with resistance to caries.


Growth of mosquito tissues in vitro.

Growth of mosquito tissues in vitro.


Inhibitor binding analysis of dihydrofolate reductases from various species.


Influence of turnover rates on the responses of enzymes to cortisone.


Inability of metabolizable oils to mimic corpus allatum hormone stimulation of ovarian development in mosquitoes.


Psychodrama as a treatment for hospitalized patients: a controlled study.


The use of hallucinogenic drugs among college students.


Spectrophotometric and manometric studies of NADPH and NADH oxidase activities of rat liver microsomes: effects of drugs and adenine nucleotides.


Geographic distribution of dental caries with particular reference to situation in Finland.


Histochemical demonstration of 11-beta-hydroxysteroid dehydrogenase.


Phosphorylase activity and glycogen, glucose-6-phosphate, and lactic acid content of human skeletal muscle in various myopathies.


Pyridine nucleotides in the thyroid. V. An artifactual effect of thyroid stimulating hormone in thyroid homogenate.


Effects of altered thyroid function in rats upon the formation and distribution of tyrosine.


Bone density and dental caries.

Bone density and dental caries.


Effects of enzymes on Yucca glauca Nutt. and other steroid-yielding monocotyledons.


Influence of temperature on the responses of the guinea-pig hypogastric nerve-vas deferens preparation.


Twitch responses with acetylcholine in the isolated innervated and chronically denervated rat diaphragms and their modification by neuromuscular blocking agents.


The mechanism underlying potentiation of the pressor action of noradrenaline by some drugs which depress sympathetic tone.


Chemical fractionation of phosphorus-32 labelled cells of Micrococcus lysodeikticus treated with chlorhexidine.


Influence of hemicholinium No. 3 on mammalian tissue levels of acetylcholine.


Pharmacological properties of isoidide dinitrate.


Action of the neurohypophysial hormones on the vascular system of the male monkey and the rooster.


Potential reserpine analogues. Derivatives of reduced isoquinolines and meconine.


Spectral slit width and the absorption of light by substances in the Addendum 1964 to the British Pharmacopoeia 1963.


Antagonism of analgesics by amine-depleting agents.


Vincamajine, the major alkaloid of leaves of Rauwolfia mannii Stapf.


Rapid release of 3H-metaraminol induced by combined treatment with protriptyline and reserpine.


Energy-linked pyridine nucleotide reduction: inhibitory effects of hyperbaric oxygen in vitro and in vivo.


Evidence for a genetic alteration of dihydrofolate reductase associated with amethopterin resistance in Diplococcus pneumoniae.


Differential action of thyroid hormones on enzyme levels of the DPN and TPN specific isocitrate dehydrogenase.


Inhibition of the TPNH-linked lipid peroxidation of liver microsomes by drugs undergoing oxidative demethylation.


Comparison of oxidation rates of reduced pyridine nucleotides by normal and respiration deficient mutant yeast.


Evidence for the involvement of iron in the ADP-activated peroxidation of lipids in microsomes and mitochondria.


The polysaccharide of Shigella dysenteriae and its cross-reactions with antisera to the pneumococcal types II and VI.


Pharmacology of oxazepam (Serax), a new anti-anxiety agent.


The immunological behaviour of mature C57BL-6J mice thymectomized at birth.


Effect of antihistaminic agents on gastric secretion in dogs.


The Dubin-Johnson syndrome in a Timorese. A case report from the Queen Elizabeth Hospital, Jesselton, Sabah.


Hydra: induction of supernumerary heads by isolated neurosecretory granules. Neurosecretory granules of Hydra littoralis were isolated by differential centrifugation. Excised midsegments of hydra that were exposed to the fraction containing neurosecretory granules developed additional heads at any site, as they regenerated. Hence neurosecretory granules may contain a factot that regulates or stimulates growth in normal and regenerating hydra.


The microbial oxidation of methanol. 2. The methanol-oxidizing enzyme of Pseudomonas sp. M 27.


The computer and personality inventory.

The computer and personality inventory.


Direct incorporation of octanoate into long-chain fatty acids by soluble enzymes of Mycobacterium tuberculosis.


Allergy and epilepsy.

Allergy and epilepsy.


Changes in MMPI scale scores and an index of psychopathology following unilateral temporal lobectomy for epilepsy.


Metabolism of cortisol-4-C-14 and cortisone-4-C-14 by rat brain homogenates.


Effect of increased pressure within a right heart cul-de-sac on heart rate in dogs.


Antihistamines and vascular reactivity.

Antihistamines and vascular reactivity.


Inhibition of 5,10-methylenetetrahydrofolate dehydrogenase by the d,L-diastereoisomer of 5,10-methylenetetrahydrofolate.


Absence of direct chronotropic action of angiotensin infused into the sinus node artery.


Pharmacologic properties of antihistamines in relation to vascular reactivity.


Cardiopulmonary function during adrenergic beta receptor blockade.


A spectrofluorimetric study of the 7-hydroxylation of coumarin by liver microsomes. 1. The fluorescence characteristics of 3- and 7-hydroxycoumarin, and 7-hydroxy-and 7-methoxy-4-methylcoumarin, have been determined. 7-Hydroxycoumarin shows excited-state ionization from pH1 to 9. 2. A sensitive and specific fluorimetric method for the determination of 7-hydroxycoumarin (umbelliferone), and its application to liver homogenates and other tissue preparations, are described. 3. The enzymic hydroxylation of coumarin to 7-hydroxycoumarin has been studied by this method and the optimum conditions have been determined for rabbit-liver preparations. The enzymic activity was found in the microsomal fraction and required NADPH(2) and oxygen. Activity with NADH(2) was one-third of that with NADPH(2). 4. Addition of NADP was necessary for full activity of 10000g supernatant preparations of liver. Nicotinamide added during preparation preserved coenzymic activity in tissue stored at -12 degrees . Glucose 6-phosphate had no effect on the activity of stored or fresh tissue. 5. Inhibition occurred with p-chloromercuribenzoate, and with the usual inhibitors of the microsomal drug-metabolizing enzymes, SKF acid, SKF 525A, and Lilly 7132, but not with 2,2'-bipyridyl. 6. Liver homogenates from rabbit, guinea pig, coypu, cat and pigeon showed activity, but preparations of rat or mouse liver, and of locust fat bodies, did not hydroxylate coumarin to umbelliferone. The enzyme system was absent from rat-liver homogenates and microsomal preparations. Moreover, rat liver also contained inhibitors of the rabbit-liver coumarin-7-hydroxylase system and of the further metabolism of umbelliferone by guinea-pig liver. Guinea-pig-liver preparations hydroxylated coumarin to umbelliferone and then converted this product into its glucuronide. 7. The coumarin-7-hydroxylase activity of female rabbit liver was two to three times that of male rabbit liver.


Dehydrogenation of androsterone by purified 3-alpha-hydroxy steroid-dependent nicotinamide-adenine dinucleotide (phosphate)-transhydrogenating enzyme of rat liver. 1. An enzyme from rat liver, catalysing 3alpha-hydroxy steroid-dependent NAD(P) transhydrogenation and NAD-linked and NADP-linked dehydrogenation of 3alpha-hydroxy steroids, has been purified 100-fold by chromatography on DEAE-cellulose and calcium phosphate gel. 2. No separation of these activities into different protein fractions has been achieved. 3. The properties of the enzyme in catalysing NAD-linked and NADP-linked dehydrogenation have been compared, with androsterone as substrate. Differences were found in pH optima, affinity for coenzyme and steroid, equilibrium constants and effects of salts. 4. NAD-linked dehydrogenation is inhibited by NADPH(2) but is protected from this inhibition by chloride, which alone is itself an inhibitor. 5. The relevance of these findings to the problem of the number of enzymes involved in catalysis of 3alpha-hydroxy steroid-dependent transhydrogenation is discussed.


Penicillins.

Penicillins.


Studies on carbonic anhydrase. II. Occurrence of the enzyme in some invertebrates.


The activities of nicotinamide mononucleotide adenylyltransferase and of nicotinamide-adenine dinucleotide kinase in the livers of rats subjected to different hormonal treatments. 1. The activities of NMN adenylyltransferase and of NAD(+) kinase have been measured in the livers of adrenalectomized or alloxan-diabetic rats and in the livers of rats treated with glucagon, pituitary growth hormone or thyroxine. 2. The activities of these enzymes have been compared with the effects of the same treatments on the nicotinamide nucleotide concentrations in the liver. 3. Alloxandiabetes (+37%) and thyroxine (+27%) both increased the activity of NMN adenylyltransferase. The other treatments were without effect on this enzyme. 4. Only thyroxine increased the activity of NAD(+) kinase significantly (+26%) although both adrenalectomy and glucagon tended to increase its activity. 5. The activity of NAD(+) glycohydrolase was measured in the livers of diabetic rats, and in the livers of rats treated with either growth hormone or thyroxine. Of these treatments, only growth hormone altered the enzyme activity (+26%, calculated on a total hepatic activity basis). 6. Female rats had a greater hepatic NAD(+)-kinase activity than males but there was no sex difference with respect to NMN adenylyltransferase. 7. The lack of correlation between the maximum potential activity of these three enzymes and the known changes of the nicotinamide nucleotides in each of the hormone conditions is discussed.


The use of the laboratory.

The use of the laboratory.


The use of antibiotics in bronchitis.

The use of antibiotics in bronchitis.


Use and abuse of antibiotics in general practice.


The treatment of urinary infections.

The treatment of urinary infections.


Mercy Hospital, Des Moines. Clinicopathologic conference.


The use of antibiotics in paediatrics.

The use of antibiotics in paediatrics.


Changes in thiol content of the hamster cheek pouch after x-irradiation and some speculations on the relationship between phospholipids and protein thiol groups.


Acquiescence and the vanishing variance component.


Item popularity and social desirability in the MMPI.


Oxidized and reduced pyridine nucleotides, and oxidation of the carbon-1 and carbon-6 of glucose, in the developing retina.


Steatorrhoea in vascular insufficiency of the small intestine. Five cases of polyarteritis nodosa and allied disorders.


The metabolic alkalosis following aspiration of gastric acid secretion.


Electron transport systems in microsomes. Origin and functional nature of microsomes.


Modification of vasodepressor responses to adrenaline by drugs.


The pharmacologic and toxicologic evaluation of the ganglionic blocking agent, dibutadiamin.


Microsomal mixed-function oxidations: the metabolism of xenobiotics.


Monoamine oxidase inhibitor reversal of parathion extension of hexobarbital action.


Microsomal TPNH-cytochrome c reductase.

Microsomal TPNH-cytochrome c reductase.


Function of cytochrome P-450 of microsomes.


The effect of adrenalectomy on the metabolism of the mammary glands of lactating rats.


Substrate-induced synthesis of the hydroxylating enzyme system of liver microsomes.


The effect of reserpine on the metabolism of glucose by mammary glands from rats after weaning.


The biochemistry of aromatic amines. 10. Enzymic N-hydroxylation of arylamines and conversion of arylhydroxylamines into o-aminophenols.


Fatty acid synthesis in cell-free preparations of rat liver containing phosphorylating mitochondria.


Effectiveness of a single application of stannous fluoride after toothbrushing.


Clinical evaluation of the dental aspects of familial dysautonomia: a preliminary report.


Parents as dispensers of aversive stimuli.


The effect of ethionine on the synthesis of nicotinamide-adenine dinucleotide and nicotinamide-adenine dinucleotide phosphate in rat liver.


Changes in liver nucleotide concentrations in experimental liver injury. 1. Carbon tetrachloride poisoning.


Changes in liver nucleotide concentrations in experimental liver injury. 2. Acute ethanol poisoning.


Measurement and conditioning of perceptual defense, response bias, and emotionally biased recognition.


Studies on the isocitrate dehydrogenase. I. Some properties of isocitrate dehydrogenase of beef heart muscle.


Effect of cofactors, oestrogens and magnesium ions on the activity and stability of human glutamate dehydrogenase.


Social desirability correlates of social responsibility.


Some serological characteristics of normal incomplete cold antibody.


Nicotinamide coenzyme concentrations in livers of normal, starved and alloxan-diabetic rats.


Clinical experience with dexchlorpheniramine in ortorhinolaryngology.


What Medicare is all about.

What Medicare is all about.


Tuberculosis among children.

Tuberculosis among children.


Grand mal epilepsy associated with chronic systemic schistosomiasis.


New horizons in schizophrenia.

New horizons in schizophrenia.


Advances in otology.

Advances in otology.


Management of pain in acute and chronic orthopedic conditions.


Adenocarcinoma of the appendix.

Adenocarcinoma of the appendix.


Leukemia in children.

Leukemia in children.


Coronary thrombosis.

Coronary thrombosis.


Disability evaluation.

Disability evaluation.


The biochemistry of animal cells. II. Lipid biosynthesis in dispersed rat liver cells.


Blood-pressure and heart-rate changes in dogs during hypothalamic self-stimulation.


Some pharmacologic properties of thozalinone, a new excitant.


Phenobarbital-induced synthesis of the microsomal drug-metabolizing enzyme system and its relationship to the proliferation of endoplasmic membranes. A morphological and biochemical study. Liver microsomes, isolated from rats which had been treated with phenobarbital in vivo, were found to exhibit increased activities of oxidative demethylation and TPNH-cytochrome c reductase and an increased amount of CO-binding pigment. Simultaneous administration of actinomycin D or puromycin abolished the phenobarbital-induced enzyme synthesis. Increased rate of P(i) (32) incorporation into microsomal phospholipid was the first sign of phenobarbital stimulation and appeared 3 hours after a single injection of this drug. Microsomes were divided into smooth-surfaced and rough-surfaced vesicle fractions. The fraction consisting of smooth-surfaced vesicles exhibited the greatest increase in protein content and oxidative demethylation activity after phenobarbital administration in vivo. Ultrastructural studies revealed that drug treatment also gave rise to proliferation of the endoplasmic reticulum in the hepatic parenchymal cells, first noticed after two phenobarbital injections. The phenobarbital-induced synthesis of the metabolizing enzymes is discussed with special reference to the relationship to the stimulated synthesis of the endoplasmic membranes.


Immunological studies on Nippostrongylus brasiliensis infection in the rat: the role of local anaphylaxis.


Urinary vesicovascular reflex.

Urinary vesicovascular reflex.


Progress in the epidemiology of dental caries.


Visual disturbance following fifth nerve ganglion injection. Report of two cases.


Influence of aminonucleoside on the pyridine nucleotide concentration of the rat kidney.


Purification and properties of chicken liver D-3-phosphoglycerate dehydrogenase.


On the interpretation of the absorption spectra of flavoproteins with special reference to D-amino acid oxidase.


20-alpha-hydroxysteroid dehydrogenase of testes.


Nursing care of the geriatric patient.

Nursing care of the geriatric patient.


Clinical diaries... as part of the teaching-learning process.


Education in research for nurses.

Education in research for nurses.


Student-directed nursing care plan project.


Preparing a manuscript.

Preparing a manuscript.


Recommendations for nursing education to relieve the nursing shortage in North Carolina.


The effect of concentration on glucose phosphorylation and incorporation into glycogen in the livers of foetal and adult rats and sheep.


Tissue fractionation studies. 17. Intracellular distribution of monoamine oxidase, aspartate aminotransferase, alanine aminotransferase, D-amino acid oxidase and catalase in rat-liver tissue.


Tissue fractionation studies. 18. Resolution of mitochondrial fractions from rat liver into three distinct populations of cytoplasmic particles by means of density equilibration in various gradients.


The induction and repression of amino acid oxidation in Pseudomonas fluorescens.


Requirements of the cholesterol side-chain-cleaving enzyme system of rat-testis mitochondria.


Stimulation of the rat ovary by gonadotropins and separation of steroids by gas chromatography.


The formation of cholic acid from 3-alpha, 7-alpha, 12-alpha, 24-xi-tetrahydroxycoprostanic acid by rat liver.


The effect in vitro of anterior pituitary hormones on glucose metabolism and pyridine nucleotide levels of lactating rat mammary gland.


The differential effects of glucocorticoid on tissue and plasma amino acid levels.


Surface specializations of hydra cells: the effect of enzyme inhibitors on ferritin uptake.


Cortisone-provoked depression of plasma tyrosine concentration: relation to enzyme induction in man.


Automatic cell changer for enzyme assay by recording fluorometry and its use with dihydrofolic reductase.


Microseparation of glycogen, sugars, and lipids.


Steroid hydroxylations. II. Intracellular location of 17-alpha-hydroxylase and its substrate specificity in sow ovary.


Gel filtration properties of mutant and wild-type dihydrofolate reductase from Diplococcus pneumoniae.


NADPH-cytochrome554 reduction by NADP-reductase and ferredoxin isolated from the diatom, Navicula pelliculosa.


The reduction of pantethine by an extract of camel intestine.


DDT ingestion and liver glucose 6-phosphate dehydrogenase activity. II.


A tryptophan hydroxylase in cell-free extracts of malignant mouse mast cells.


Effect of chronic sympathetic denervation on subcellular distribution of some sympathomimetic amines.


Pneumococcal types detected in throat cultures from a population of "normal" families.


Studies on antinuclear antibodies.

Studies on antinuclear antibodies.


Early changes of hexose monophosphate pathway activity and of NADPH oxidation in phagocytizing leucocytes.


On the nicotinamide nucleotide specificity of glutamate dehydrogenase in rat-liver mitochondria.


The circulatory effects of pronethalol with special reference to changes in heart rate and stroke volume during exercise.


Oxidation of methylglyoxal to pyruvic acid by a sheep-liver enzyme.


Effects of central depressants and stimulants on EEG alterations induced by carotid cooling and warming.


Effects of dichloroisoproterenol and phenoxybenzamine on the transmembrane potentials of the isolated rabbit's heart.


Sympathomimetic effects of dichloroisoproterenol.


Action of pronethalol on neuromuscular activity.


On the hypotensive effect of tranylcypromine.


The agar gel-diffusion technique as a method of differentiating mosquito larvae.


Classification of sympathomimetic drugs on the rabbit intestine.


Maternal control as related to schizoid behaviors in grossly normal males.


The organization of a memory system.

The organization of a memory system.


Optomotor response studies of insect vision.


The transmission of anti-Brucella abortus agglutinins across the gut in young rats.


Hernie-en-glissade of the small bowel with imperfect descent of testis (a case report).


Epidemiology of emotional disturbance in a men's college.


Amino acids in extracellular fluids of Physalia physalis and Aurelia aurita.


Aldosterone stimulation in vitro. II. Stimulation of aldosterone production by monovalent cations.


Benzhydrylpiperazine antihistamines, hydramnios, and congenital malformations in the rat.


Self-rating depression scale in an outpatient clinic. Further validation of the SDS.


The purification and properties of the fatty acid synthetase of pigeon liver.


Mixed function oxidation. IV. An induced methylene hydroxylase in camphor oxidation.


Studies on crystalline D-amino acid oxidase. II. Isolation of a reduced 14C-labeled substrate-enzyme intermediate after the action of sodium borohydride.


The mechanism of 1- and 2-electron transfers catalyzed by reduced triphosphopyridine nucleotide-cytochrome c reductase.


4,4'-Dibromodiphenyldisulfimide as a reagent for the identification of organic bases. II. Optical crystallographic properties of derivatives of some antihistamines.


A new look at migraine.

A new look at migraine.


Notes.

Notes.


Migraine in a rural practice (1958-1963). A five-year study of a controlled clinical trial.


Anaemia in patients admitted to a geriatric unit.


Epidemic measles. Modification by killed virus vaccine, given two years previously.


The general practitioner, the social worker and the health visitor.


Prevalence of inflammation of the urinary tract.


Comparative studies of the gonad in testicular feminization and cryptorchidism.


A study of purpose built group practice premises.


Candidates for exfoliative cytology of the cervix.


A fatal case of carcinoma in a young man.


A trial of imipramine in the treatment of psoriasis.


Medical Commission on Accident Prevention-home accidents. A review of selected literature, 1948-1964. The causes of accidents to pre-school age children.


Group health education in a general practice.


Case records of the Massachusetts General Hospital. Case 50-1965.


Lymph node permeability factor in the dinitrochlorobenzene skin hypersensitivity reaction in guinea-pigs.


Oxidation of 14-C-1 and 14-C-6-glucose by hormone synthesizing and hormone secreting portions of neurohypophysial neurons.


Antibacterial activity of penicillin. I. The nature of the activity of different acyl derivatives of 6-aminopenicillanic acid.


Metabolism of trichloroethylene in liver microsomes. I. Characteristics of the reaction.


Temperature independence of the composition of triglyceride fatty acids synthesized de novo by the mosquito. The hypothesis that depot fat is more unsaturated when it is synthesized at lower temperatures was tested in the mosquito. Female mosquitoes (Aedes sollicitans) were starved until no triglycerides remained. A single dose of sugar was fed and the mosquitoes were maintained at different temperatures. Approximately the same amount of triglyceride was synthesized per mosquito at each temperature, although at different rates. Mosquitoes maintained at low temperatures did not synthesize more unsaturated triglycerides than those at higher temperatures: the fatty acid composition was essentially the same from 10 to 35 degrees. The triglycerides synthesized from sugar contained no poly-unsaturated fatty acids. Total amounts and composition of phospholipid fatty acids remained unaltered during sugar feeding. When deprived of food, the mosquitoes catabolized triglyceride fatty acids randomly; cold-exposure did not cause selective retention or utilization of any individual fatty acid.


Effect of saturated fat diets on rat liver NADP-linked enzymes.


A mechanism of action of the gonadotropins.


Studies on artificial cryptorchidism: compensatory changes in the scrotal testes of unilaterally cryptorchid rats.


Studies on artificial cryptorchidism: the histological appearances of unilateral and bilateral abdominal testes in the rat.


Infant feeding method and adolescent personality.


Polyendocrine adenomatosis with the Zollinger-Ellison syndrome. Successful treatment by total gastrectomy with a Lawrence pouch.


Dentistry in relation to social factors.


Effect of drugs and insecticides on the anesthetic action of steroids.


Relation of the ovary to adrenal corticosterone production and adrenal enzyme activity in the rat.


Diagnosis and treatment: the undescended testicle.


Neomycin blood agar for the selective culture of Pneumococcus and certain other bacteria.


Cytochrome b5 and related oxidative activities in mammalian brain microsomes.


Action of puromycin and 5-fluorouracil on the adrenal responsiveness to corticotrophin.


Influence of an adrenergic beta-receptor blocking agent on the effect of various hypotensive agents in the hypertensive rat.


Bacterial infection and some effects of Chemoprophylaxis in chronic pulmonary emphysema. II. chemoprophylaxis with daily chloramphenicol.


Studies on the function of N-acetyl aspartic acid in brain.


Cutaneous vasculitis in mother and infant.


The effects of reserpine and of adrenolytic agents on the pulmonary arterial pressor response to serotonin.


Cryoglobulinaemia in rabbits hyperimmunized with a polyvalent pneumococcal vaccine.


Equipotent alveolar concentrations of methoxyflurane, halothane, diethyl ether, fluroxene, cyclopropane, xenon and nitrous oxide in the dog.


Stimulation of steroid C-11-beta and C-18 hydroxylations in rat adrenal homogenates by adenosine 3',5'-phosphate via a mechanism not requiring endogenous precursor, glycogen phosphorylation or NADPH generation.


Catabolism of C19-steroids by subcellular fractions of mammalian and avian tissues. I. Hydroxylation of ring A-saturated substrates by rat-liver microsomes.


Fetal liver as an endocrine tissue.

Fetal liver as an endocrine tissue.


Anticholinesterase activity of tropeine derivatives.


Inhibiting and enhancing effect of various chemical agents on rat's resistance to inoculated Walker 256 tumor cells.


Toxic hazards research unit. Design and construction phase. AMRL-TR-65-125.


Application of lithium chemicals for air regeneration of manned spacecraft. AMRL-TR-65-106.


Research and development of a continuous atmospheric measurement system. AMRL-TR-65-75.


The development of gas and liquid circulating devices for manned space enclosures. AMRL-TR-65-128.


Feasibility investigation of viscous solvent removal of trace contaminants. AMRL-TR-65-100.


Potassium superoxide atmosphere control unit. AMRL-TR-65-44.


Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 5. Uterine manifestations of interference with hormonal requirements of deciduomata.


3-alpha-hydroxysteroid dehydrogenation in subcellular fractions of rat ventral prostate and other tissues.


Pathways of enzymic synthesis and conversion to cholesterol of delta-5,7,24-cholestatrien-3 beta-ol and other naturally occurring sterols.


Purification and properties of 5,10-methylenetetrahydrofolate dehydrogenase from Escherichia coli.


On the reaction mechanism of yeast glutathione reductase.


Adenosine 3',5'-monophosphate in biological materials. II. The measurement of adenosine 3',5'-monophosphate in tissues and the role of the cyclic nucleotide in the lipolytic response of fat to epinephrine.


The development of a scale for rating clinical performance.


Psychological content in nursing curricula.


Education today for nursing service tomorrow.


Career decisions of student nurses in Japan.


Synthesis of several mesoionic 1,3,4-thiadiazoles.


Blood clotting studies in a submarine crew. Serial analysis of the clotting mechanism during prolonged submergence.


Item subtlety in personality inventory scales.


Prediction of mental illness in college students on the basis of "nonpsychiatric" MMPI profiles.


MMPI findings for cerebral palsied college students.


Design of a test model for a solid electrolyte carbon dioxide reduction system. AMRL-TR-65-153.


Dental caries and dental fluorosis in Thailand.


The nature of the vasodilation which follows arterial gas embolization.


Beta-adrenergic blockade in the treatment of exercise-induced paroxysmal ventricular tachycardia.


Parole outcome as predicted from the CPI, the MMPI, and a base expectancy table.


Abdominal apoplexy in polyarteritis nodosa. Report of a case.


Fluoromar: I. Anesthetic for otologic surgery. A series presentation and discussion of technic.


Teratogenic effect of meclizine, cyclizine, and chlorcyclizine.


Enlightening report of international meet.


The effect of alkyl substitution in drugs. 13. The effect of alkyl-substituted N,N-dimethyl-2-[alpha-(2-pyridyl)benzyloxy]ethylamines on the metabolism of rat brain tissue.


Studies on pyridine nucleotides in photosynthetic tissue. Concentrations, interconversions, and distribution.


Antihistamine activity of N,N-dimethyl-N'-phenyl-N'-(selenyl-2)-ethylenediamine hydrochloride.


On the problem of acid-labile triphosphopyridine nucleotide in biological material.


The reduction step in diaminopimelic acid biosynthesis.


Cardiovascular activity of mecamylamine, pempidine, and several pempidine analogs.


Interaction between some anticholinergic agents and phenothiazines. Potentiation of phenothiazine sedation and its antagonism.


Treatment of migraine with meclofenoxate.


Further metabolic studies of hydrocortisone-4-14C in human skin: requirement for pyridine nucleotides and sites of metabolism.


Biliverdin reductase of guinea pig liver.


Adhesive strips in the closure of wounds in outpatient surgery in children.


A new anti-fatigue agent in general practice.


ICN 13th quadrennial Congress.

ICN 13th quadrennial Congress.


Endotoxin-induced susceptibility to staphylococcal infection and its reversal by adrenergic blocking agents. Sultzer, Barnet M. (Princeton Laboratories, Inc., Princeton, N.J.), and Henry H. Freedman. Endotoxin-induced susceptibility to staphylococcal infection and its reversal by adrenergic blocking agents. J. Bacteriol. 90:1001-1006. 1965.-The transient phase of increased susceptibility to bacterial infection in mice provoked by prior administration of small doses of endotoxin was investigated for possible mediation by vasoactive substances. Animals were given endotoxin intravenously shortly before intraperitoneal injection of Staphylococcus aureus Smith, thereby lowering the lethal inoculum 10-fold. To determine whether this susceptibility state could be obviated, mice were pretreated with phenoxybenzamine or dibenzylchlorethylamine. Mortality decreased from an average of 81% in the endotoxin control groups to about 23% in the treated mice, closely approximating the mortality in control mice injected with saline and staphylococci. Neither antiadrenergic agent independently altered the resistance of mice to a higher lethal staphylococcal challenge, nor did these materials induce extravascular leukocyte mobilization into the peritoneal cavity. The results suggest a possible role of vasoactive staphylococcal alpha-toxin, as well as epinephrine or epinephrine-like factors, in this altered state of resistance to staphylococcal infection.


Abnormalities of the urinary tract. Clinical comments based on experiences in private practice.


Renal hemodynamics and metabolism in chronic experimental renal ischemia, with and without hypertension, and their alteration by ganglionic blocking agents.


Stimulation of muscle spindle afferents by DMPP.


Stimulation by chlordane of hepatic drug metabolism in the squirrel monkey.


Interaction of antihistaminics with norepinephrine uptake: a cocaine-like effect.


Relative frequencies of different kinds of spontaneous and induced mutants of pneumococci and streptococci capable of growth in the presence of streptomycin. Ravin, Arnold W. (University of Rochester, Rochester, N.Y.), and Ajit K. Mishra. Relative frequencies of different kinds of spontaneous and induced mutants of pneumococci and streptococci capable of growth in the presence of streptomycin. J. Bacteriol. 90:1161-1173. 1965.-Mutations conferring ability to grow in the presence of streptomycin arise spontaneously and can be induced in pneumococci and streptococci. They prove to be of several phenotypic and genetic types, which may be classified as follows: VLR, LR, and HR, which confer resistance, respectively, to less than 50, between 50 and 500, and 500 or more mug/ml of streptomycin. VLR and LR mutations recombine with each other, whereas HR mutations generally replace (do not recombine with) several of the VLR and LR mutations. Spontaneously, the VLR type is several times more frequent than the LR and HR types, which are equally frequent relative to each other. Nitrous acid treatment of deoxyribonucleic acid (DNA) in vitro or ultraviolet irradiation of cells tends to produce the VLR and LR type of mutation. Streptomycin-dependent mutations are rare in the pneumococci and streptococci. One such mutation, requiring 500 to 1,000 mug/ml of streptomycin for optimal growth, arose spontaneously in a group A streptococcal strain, and was transferred via a DNA-mediated transformation to a pneumococcal strain. In the latter, the mutation proved to be very closely linked to the genetic locus at which the streptomycin-resistance mutations arise.


Relationship between the competence antigen and the competence-activator substance in pneumococci. Tomasz, Alexander (The Rockefeller Institute, New York, N.Y.), and Samuel M. Beiser. Relationship between the competence antigen and the competence-activator substance in pneumococci. J. Bacteriol. 90:1226-1232. 1965.-Antisera prepared against pneumococci in their competent phase inhibit deoxyribonuoleic acid (DNA)-mediated genetic transformation as well as binding of radioactive DNA by the cells. The same sera do not inhibit transformation of competent Haemophilus influenzae and Bacillus subtilis cells, but transformation of a Streptococcus strain genetically related to pneumococci is inhibited. The kinetics of immune inhibition of transformation resembles the inactivation of bacteriophage by phage-neutralizing antisera. The appearance of the competence antigen on the surface of pneumococci can be induced by the competence-activator substance. Antisera prepared against competent pneumococci can also inhibit the conversion of incompetent cells to competence by the competence-activator substance. The possibility is considered that part of the new antigenic determinant appearing on the cell surface during competence may be the activator itself.


Immunological paralysis against type 8 and immunity against type 3 Diplococcus pneumoniae induced by the soluble specific substance of type 8. Brooke, Marcus S. (Massachusetts Institute of Technology, Cambridge). Immunological paralysis against type VIII and immunity against type III Diplococcus pneumoniae induced by the soluble specific substance of type VIII. J. Bacteriol. 90:1296-1303. 1965.-Mice injected with relatively large quantities of the soluble specific substance of type VIII Diplococcus pneumoniae (SVIII) are, on the basis of challenge experiments, paralyzed against type VIII but immune against type III D. pneumoniae. Their sera contain antibodies which react with sheep cells coated with SIII. Unfortunately, it was not possible to develop an in vitro test with SVIII. When the SVIII was treated with a specific SVIII depolymerase before injection into mice, the sera still contained antibodies against SIII and some protection was afforded these mice against type III but not against type VIII challenge. When the SVIII was treated with a specific SIII depolymerase, antibodies were not detectable and the mice were not protected against type III or type VIII challenge. On the basis of these results it is suggested that either the SVIII strain is a hybrid forming both SVIII and SIII molecules or that part of the SVIII chain is altered to consist of repeating units of cellobiuronic acid rather than alternating units of cellobiuronic acid and the disaccharide galactose-glucose. The quantity of SIII in some preparations of SVIII is calculated to be of the order of 0.01%. It is not clear whether all type VIII strains at all times possess the capacity to elicit antibodies which react specifically against SIII, or if this is the property of only some strains and some preparations of these strains.


Ego control patterns and attribution of hostility to self, parents, and others.


Perceptual investigation of psychoanalytic theory concerning latent homosexuality in women.


Crystallization and some properties of D-amino acid oxidase apoenzyme.


A problem in bacterial endocarditis.

A problem in bacterial endocarditis.


The bacterial induction of homograft sensitivity. II. Effects of sensitization  with staphylococci and other microoorganisms. Heat-killed strains of Staphylococcus aureus and Staphylococcus albus can induce in guinea pigs a state of altered reactivity to skin homografts which is indistinguishable from that which results from sensitization with homologous tissues or Group A streptococci. Challenge of suitably prepared recipients with first-set skin homografts obtained from unrelated randomly selected donors elicits white graft reactions or accelerated rejection of such grafts. Other bacteria tested included Lancefield streptococcal groups B, C, D, E, G, H, L, and O, pneumococcus Types II, III, XIV and a rough strain, Corynebacterium xerosis, Bacillus subtilis, Escherichia coli, Aerobacter aerogenes, Salmonella typhimurium, Proteus vulgaris, Neisseria catarrhalis, Haemophilus influenzae, and two human virulent strains of Mycobacterium tuberculosis. None of these microorganisms was active in the induction of homograft sensitivity in the guinea pig. Pretreatment of recipients with Gram-negative bacterial suspensions was associated with a slight increase in the mean survival time of first-set skin homografts. Results of this study suggest the presence in staphylococci, as well as in Group A streptococci, of antigens related in their biologic effects to tissue transplantation antigens.


Histochemical utilization of 3-alpha-, 6-beta-, 12-alpha-, 16-alpha-, 16-beta-, 17-alpha-, 21- and 24 hydroxysteroids.


Depression of adrenal corticosterone production in oophorectomized rats.


Integration efficiency and genetic recombination in pneumococcal transformation.


Reaction of peroxidase with reduced nicotinamide-adenine dinucleotide and reduced nicotinamide-adenine dinucleotide phosphate.


Purification and properties of N5, N10-Methylenetetra-hydrofolate dehydrogenase of calf thymus.


The effects of alpha and beta adrenergic blockade on the lethality of amphetamine in aggregated mice.


Biochemical aspects of phagocytosis in polymorphonuclear leucocytes. NADH  and NADPH oxidation by the granules of resting and phagocytizing cells.


Drugs: the medical care program's biggest headache.


Acute and chronic German measles.

Acute and chronic German measles.


Iprindole, a new antidepressant for use in general office practice. A double blind, placebo-controlled study.


Rupture of the pregnant uterus with delayed treatment.


A short method for blood glucose determination.


A long-term study of diabetics treated with chlorpropamide.


Sporotrichosis.

Sporotrichosis.


Treatment of an unusual extensive thermal burn.


Recent advances: blood group incompatibility of the newborn.


Massive bleeding peptic ulcer. Mortality in the aged.


The satirists' war on medicine.

The satirists' war on medicine.


Endobronchial lipoma. Report of a case and review of the literature.


Acute hemorrhagic pancreatitis: beneficial effects of primary excision of grossly necrotic pancreatic tissue.


Management of snake bite cases.

Management of snake bite cases.


New isolations of P. cynomologi and P. inui from A. b. balabacensis in Perlis.


Studies of the migration pattern of infective Brugia pahahgi larvae by the ligation method.


Human tooth mortality: a clinical-statistical study.


Comparative study of tadpole and frog glutamate dehydrogenases.


Metabolism of isolated fat cells. II. The similar effects of phospholipase C (Clostridium perfringens alpha toxin) and of insulin on glucose and amino acid metabolism.


The metabolism of reduced pyridine nucleotides in tumor tissue.


The conformation of pyridine dinucleotides in solution.


The natural history of testicular descent.


Autoimmune diseases in domestic animals.


The Brantford-Sarnia-Stratford fluoridation caries study: final survey, 1963.


Transfer factor and autoimmune disease.

Transfer factor and autoimmune disease.


Dental observations on Australian aborigines, Koonibba, South Australia.


A study of dental caries in a group of Western Australian children. IV. The bilaterality of dental caries.


Light effects on oxygen evolution and phosphorylation in spinach chloroplasts.


Studies on the bioluminescence of Renilla reniformis. V. Absorption and fluorescence characteristics of chromatographically pure luciferin.


The clinical anticariogenic effectiveness of supplementary fluoride-vitamin preparations. Results at the end of three years.


Etiology of acute otitis media in infants and children. Seventy-one children were studied intensively in an attempt to identify both bacterial and viral agents responsible for acute otitis media. Studies included processing of nasopharyngeal secretions and of fluid obtained by needle aspiration of the middle ear. Ear fluid was consistently sterile for viruses but grew bacterial pathogens in 10 of 20 specimens. Nose and throat cultures yielded bacterial pathogens in less than 40% and were of little value in predicting middle-ear flora. Influenza C was isolated from one of 48 throat washings. Viral serology was compatible with influenza A2 and adenovirus infection in two cases. Bacterial and viral agents could not be incriminated in nearly 50% of the children studied.


Treatment with Neopepulsan Duplex dragée.


Procedures and problems in computer analysis of the MMPI.


Vicks formula 44 for coughs.

Vicks formula 44 for coughs.


Occurrence of alpha and beta receptors in the bile duct.


Serum level of activity of dehydrogenases of pentose phosphate cycle in certain types of pathology.


Dental caries incidence of the Okavango Bushmen.


Modification by calcium of the release of autonomic mediators in the isolated sinoatrial node.


Inotropic and metabolic effects of three beta-adrenergic receptor blocking drugs on isolated rabbit left atria.


Effects of ganglionic blocking drugs on blood glucose, amino acids, free fatty acids, free fatty acids and catecholamines at exercise in man.


Obesity. Affective changes in the fasting state.


Mediators of inflammation in leukocyte lysosomes. II. Mechanism of action of lysosomal cationic protein upon vascular permeability in the rat. The vascular permeability-increasing action of rabbit PMNL lysosomes has been studied in skin and cremaster muscle of the rat. Both an extract of frozen-thawed granules and a cathepsin-free cationic protein fraction of the granules (which had previously been demonstrated to cause leukocyte adhesion and emigration in vivo) induce increased vascular permeability in skin and muscle which resembles that produced by histamine or histamine-liberators with respect to the timing of the response and the predominant type of microvessel affected. Extracts of frozen-thawed lysosomes and the inflammatory lysosomal cationic protein both cause disruption of rat mesenteric mast cells in vitro, whereas a granule-free cytoplasmic fraction of PMN leukocytes and a non-inflammatory cationic protein fraction of the granules do not do so under identical test conditions. The mastocytolytic action of lysosomal materials in vitro is not inhibited in the presence of 10 kallikrein-inhibiting units of trasylol per ml. The mast cell rupturing fraction of PMNL granules (cationic protein) possesses no detectable peroxidase activity or acid-mucopolysaccharase activity. When compared with compound 48/80 on the basis of estimated molecular weight, the lysosomal cationic protein appears to be at least as active as the latter compound with respect to in vitro mastocytolytic potency. Chronic pretreatment of rats with an agent known to reduce tissue mast cell numbers causes marked suppression of the vascular permeability change normally induced in skin and muscle by lysosomal extracts and cationic protein. Similar results are obtained if lysosomal materials are tested in rats pretreated with an antihistaminic. These observations are discussed with respect to the mode of action of PMNL lysosomes in the early and late phases of local tissue-injury reactions.


Positive inotropic effect of manganese on dog myocardium.


Staphylococcal alpha-toxin-induced contraction of isolated arterial smooth muscle.


Clinicopathological conference: University of Florida College of Medicine.


Fatty acid biosynthesis in human erythrocytes: evidence in mature erythrocytes for an incomplete long chain fatty acid synthesizing system.


Pyridine nucleotides in erythrocyte metabolism.


Histamine as the potential mediator of active reflex dilatation.


Niacin metabolism in mycobacteria. Mechanism of excess niacin production by human tubercle bacilli.


Asian influenza. Infection, disease, and psychological factors.


Female pseudo-hermaphrodite presenting with bilateral cryptorchidism.


The histochemical demonstration of uricase activity.


Viruses of the California encephalitis complex in indicator rabbits.


Follow-up studies of St. Louis encephalitis in Florida: serologic findings eighteen months to five years after epidemics.


Spheroplast-like cells of pneumococci.

Spheroplast-like cells of pneumococci.


Evidence for beta receptors in the rat mesenteric microvasculature.


Evaluation of various adrenergic blocking agents in isolated rabbit and turtle hearts.


The effect of thiopental on hepatic glycogen phosphorylase.


Some aspects of the cardiac actions of reserpine and pronethalol.


Drug-induced modifications of discriminated avoidance behavior in rats.


Thermal integration of electrical power and life support systems for manned space stations. NASA CR-316.


Studies on the various glands of the tick Haemaphysalis spinigera Neumann 1897. 3. The salivary glands.


Biting ceratopogonids as vectors of human and animal diseases.


A comparison of two subsidiary tasks used to measure fatigue in car drivers.


Development of a new set of MMPI scales.


Interpreting the MMPI L scale.

Interpreting the MMPI L scale.


Functioning on the Yeshiva College Subcultural Scale (YCSS) of Jewish students enrolled in a Jewish school of social work.


A review of the MMPI in industry.

A review of the MMPI in industry.


Effects of response sets on new and old MMPI scales.


Histochemical distribution of 3-beta-hydroxysteroid dehydrogenase and 17-alpha-and 17-beta-hydroxysteroid dehydrogenases in the placenta and foetal membranes of the rat.


Cortisol secretion by the dog adrenal: effects of cyclic adenosine monophosphate, dichloroisoproterenol, dihydroergotamine and adrenaline.


Transmitter released in the cat uterus by stimulation of the hypogastric nerves.


Physiological and pharmacological interactions of antihypertensive drugs. The complex mechanisms that maintain the blood pressure can be interfered with at many points by drugs. A drug acting at one point may be potentiated by another which blocks a compensatory reflex minimizing the effect of the first. Many therapeutically useful drug combinations have a nonspecific mechanism of this kind although drugs that act upon different points in the sympathetic efferent vasomotor pathway have not been proved to have a useful additive effect.It is not easy to prove a synergistic action of two drugs unless it is large. The best supported examples are combinations of either a diuretic or a vasodilator with a sympathetic blocking drug. These combinations are the ones most widely used in treatment of hypertension. They allow the dose of each active substance to be reduced so that unwanted side-effects are decreased without losing the desired action on the blood pressure.Drug combinations have special risks besides their obvious advantages. Patients are more likely to become confused and take the wrong doses if their treatment regime is complicated. Two drugs which are individually nontoxic may have dangers when used together. Oliguria and a mounting blood urea may follow combined use of powerful modern diuretics. Toxic effects may be entirely unrelated to the main therapeutic action of the drug, as with the enhanced diabetogenic effect of diazoxide used with hydrochlorothiazide.Several potent cardiovascular drugs modify the response to drugs which might be given to raise the blood pressure in an emergency. No drug in common therapeutic use seriously reduces the response to injected noradrenaline but some, such as sympathetic blockers and monoamine oxidase inhibitors, greatly increase sensitivity. Pressor amines that act indirectly by noradrenaline release may be ineffective in the presence of drugs which deplete or insulate the stores of the transmitter in adrenergic nerve endings.The advantages and disadvantages of drug interactions deserve more thought and study than they usually receive.


Vasodilatation in the submaxillary gland of the cat.


Diabetes and host resistance. I. Effect of alloxan diabetes upon the phagocytic and bactericidal efficiency of rat leukocytes for Pneumococcus. Briscoe, H. Frances (University Medical Center, Jackson, Miss.), and Fred Allison, Jr. Diabetes and host resistance. I. Effect of alloxan diabetes upon the phagocytic and bactericidal efficiency of rat leukocytes for pneumococcus. J. Bacteriol. 90:1537-1541. 1965.-Chronic diabetes mellitus was induced in rats with alloxan monohydrate. Glycosuria persisted for the 6 weeks of study, but ketonuria was never encountered. The cellular composition of peritoneal exudate recovered from diabetic rats after starch aleuronat administration was the same as that obtained from normal rats. The quantity of exudate recovered from the diabetic rats was thought to be less than that obtained from normal rats subjected to the same irritant. Phagocytosis was found to be essentially the same for both diabetic and normal cells when suspended in normal saline. The killing efficiency of harvested peritoneal phagocytes suspended in saline from both diabetic and normal rats for type 1 pneumococcus was compared and no difference between the groups was found.


Biochemical effects of aromatic amines. I. Methaemoglobinaemia, haemolysis and Heinz-body formation induced by 4,4'-diaminodiphenylsulphone.


Inhibition of transaminases by cinchophen and its derivatives.


Biosynthesis of corticoids in guinea pig adrenal slices the effect of ACTH on [I-14C]acetate incorporation into adrenal steroids.


Nepuyo virus, a new group C agent isolated in Trinidad and Brazil. I. Isolation and properties of the Trinidadian strain.


Intracellular mechanisms for the control of respiration and biosynthesis in mycobacteria.


Fatal polyarteritis presenting as asymmetrical peripheral gangrene.


Effect of various procedures on the repletion of cardiac catecholamine stores after tyramine.


Metabolic capabilities and deficiencies of rickettsiae and the psittacosis group.


Dental caries rate of Mobile County school children: comparison of children in areas supplied by fluoridated and non-fluoridated communal water supplies.


The stimulation of canine prostatic secretion by pilocarpine.


The analysis of routine medical records.


An "artificial practice" as a tool for research into general practice.


The doctor-patient relationship in the surgery.


Medical practice in the days of Mackenzie.


Patterns of patient communication.

Patterns of patient communication.


The organization of a cervical screening service.


Late calls in general practice.

Late calls in general practice.


Unreliability of psychiatric patients in following prescribing instructions.


Notes on ischaemic heart disease.

Notes on ischaemic heart disease.


Some contrasts in morbidity distribution.


Metabolism of 5-hydoxytryptamine in platelet-free plasma of rabbits.


Metabolism of 5-hydroxytryptamine in blood platelets of rabbit.


Evidence for active transport of choline in rat kidney cortex slices.


Additional studies on the mechanism of action of ACTH.


Two types of 5-hydroxytryptamine release from isolated blood platelets.


The uptake and storage of H3-norepinephrine in the reserpine-pretreated rat heart.


Enzymic processes and vascular changes in the skin radiation reaction.


Role of norepinephrine release in the interval-strength relationship of heart muscle.


Periodontal disease and dental caries. Some new aetiological considerations.


Heterogeneity among glucose-6-phosphate dehydrogenase deficient mutants.


Undescended testicle.

Undescended testicle.


Determination of nicotinamide-adenine dinucleotide phosphate in blood.


On the interaction of 1-alkyl pyridinium couples.


Similar effects of DDT and convulsive hydrazides on housefly metabolism.


Effect of alpha-methyldopa and alpha-methyl-m-tyrosine on the mobilization of free fatty acids.


Effect of propranolol on the peripheral circulation.


Effect of sublethal concentrations of penicillins on the lysis of bacteria by lysozyme and trypsin.


Monoamine oxidase inhibition by a new carcinostatic agent, N-isopropyl-a92-methylhydrazino)-p-toluamide (MIH).


Some relations between minimal content, acquiescent-dissentient, and social desirability scales.


Conference of AEC meteorological activities May 19-22, 1964. BNL 914 (C-42).


Metabolism of other D- and L-hydroxy acids.


Pathways of fatty acid biosyntheses in the rabbit mammary gland.


The agar gel-diffusion technique as a method of differentiating mosquito eggs.


Fine structural changes in the nervous system of the regenerating hydra.


The effects of whole-body x-irradiation on oxidized and reduced triphosphopyridine nucleotide concentration in rat organs.


Studies on the isocitrate dehydrogenase. II. Isocitrate dehydrogenase and transhydrogenase in tumor bearing rat liver and ascites tumor cells.


The fine structural localization and selective inhibition of nucleosidephosphatases in the rat adrenal cortex.


Pyrrolnitrin, a new antifungal antibiotic. Microbiological and toxicological observations.


Morphological changes of bacteria induced by chemotherapeutic agents. 3.


Living under the sea.

Living under the sea.


Comparative aspects of some bacterial dehydrogenases and transhydrogenases. Ragland, T. E. (Brandeis University, Waltham, Mass.), T. Kawasaki, and J. M. Lowenstein. Comparative aspects of some bacterial dehydrogenases and transhydrogenases. J. Bacteriol. 91:236-244. 1966.-Twenty-eight diverse bacterial species were surveyed for the activities and coenzyme specificities of four enzymes: isocitrate dehydrogenase (ICDH), glucose-6-phosphate dehydrogenase (G-6-PDH), 6-phosphogluconate dehydrogenase (6-PGDH), and reduced nicotinamide adenine dinucleotide phosphate-nicotinamide adenine dinucleotide (NAD) transhydrogenase (TH). Most of the species that exhibited a nicotinamide adenine dinucleotide phosphate (NADP)-linked ICDH also showed significant TH activity, but there were several which did not. Only one of the organisms tested, Xanthomonas pruni, had an ICDH active with both NAD and NADP; it was devoid of TH activity. Acetobacter suboxydans, which lacks ICDH altogether, also had no TH. Some of the species examined had G-6-PDH or 6-PGDH (or both) of dual coenzyme specificity, but there was no apparent relation between these findings and the presence or absence of TH. The TH reaction was assayed by use of analogues of NAD as acceptors. The bacteria could be divided into two groups on the basis of TH specificity, one group reacting at a much faster rate with the 3-acetylpyridine analogue of NAD than with the thionicotinamide analogue, whereas the converse was true for the other group. A few organisms showed no marked specificity for either analogue. This division of specificity can be related to the currently accepted taxonomic classification of the organisms, although a few apparent anomalies were found.


Comparative carbohydrate catabolism and methemoglobin reduction in pig and human erythrocytes.


Atypical phenylketonuric heterozygote. Deficiency in phenylalanine hydroxylase and transaminase activity.


[Studies on the function of concentration maintenance (TAF). 5. An experimental study on autonomic nervous balance and TAF] (Jap].


The native, denatured and renatured states of deoxyribonucleic acid.


The action of angiotensin and bradykinin on the superior cervical ganglion of the cat.


Effect of CCl4, dimethylnitrosamine, and thioacetamide on hepatic DPNH and TPNH cytochrome C reductase.


Uptake of reduced folic acid by chicken liver enzyme.


Ingwavuma virus: an arbovirus isolated in South Africa.


[Electron paramagnetic resonance and phosphorescence measurements of the triplet state of orotic acid and related pyrimidines].


The nature of monkey cell haemagglutinins of Rosen's group II adenoviruses.


Distribution and metabolism of 32P-O, O-dimethyl-2,2,2-trichloro-1-methoxyethyl phosphonate in the adult larva of "Prodenia litura F".


Distribution of adrenergic receptors in the cat ileum.


Studies on the triphosphopyridine nucleotide-cytochrome f reductase of chloroplasts.


Purification of flavin mononucleotide-dependent enzymes by column chromatography on flavin phosphate cellulose compounds.


5-Keto-D-fructose. IV. A specific reduced nicotinamide adenine dinucleotide phosphate-linked reductase from Gluconobacter cerinus.


Absolute configuration and parasympathetic action: pharmacodynamics of enantiomorphic and diastereoisomeric esters of beta-methylcholine.


Method for evaluating spasmolytic activity of drugs on the bile duct.


Combined biochemical and morphological study of particulate fractions from rat liver. Analysis of preparations enriched in lysosomes or in particles containing urate oxidase, D-amino acid oxidase, and catalase. Six particulate preparations isolated from rat liver under different experimental conditions were analyzed biochemically and examined in the electron microscope. The results confirm the lysosomal nature of the pericanalicular dense bodies and demonstrate that the microbodies are the bearers of urate oxidase, catalase, and D-amino acid oxidase. Catalase, representing a major component of the particles, and D-amino acid oxidase appear to be associated with the structureless "sap" of the particles, urate oxidase with their crystalloid core or with their outer membrane.


Bacteriostatic actions of some tetracyclines.


Antagonism of 5-hydroxytryptamine-induced bronchospasm in guinea-pigs by 8-beta-carbobenzyloxyaminomethyl-1-methyl-10-alpha-ergoline.


Estimation of dopamine, noradrenaline, adrenaline and hydroxytryptamine from single rat brains.


Observations on the pharmacology of halquinol.


Some physical properties of lactose and magnesia.


Competitive blockade of adrenergic alpha-receptors and histamine receptors by thymoxamine.


3-Epimerisation of digoxigenin in the rat.


Inhibition of the acetylcholine-destroying activity of the guinea-pig vas deferens by eserine or by dyflos.


Solubilisation of preservatives by non-ionic detergents.


The effect of monoamine oxidase inhibition on guanethidine-induced noradrenaline release and sympathetic blockade.


Midline approach to orchiopexy.

Midline approach to orchiopexy.


The isolation and characterization of cholesterol in Portuguese Men-of-War (Physalia).


Clinical pharmacology of some parasympathicolytic drugs.


On the expansion-contraction rhythm of the sea anemone, Actinia equina L.


Retardation of corneal vascularization.

Retardation of corneal vascularization.


Restoration of NADP photoreducing activity of sonicated chloroplasts by plastocyanin.


Clinical observations on a new dihydrodibenzoxazepine (SQ 10,648) with potent antihistaminic properties.


Thyroxine-stimulated oxidative enzyme activity associated with precocious brain maturation in anurans. A histochemical study.


Clinical trials with pericyazine. (A preliminary study).