Alpha-keto aldehyde dehydrogenase, an enzyme that catalyzes the enzymic oxidation of methylglyoxal to pyruvate.


Dihydrofolate reductase from the L1210 R murine lymphoma. Further studies on the binding of substrates and inhibitors to the enzyme.


Mothers with multiple illegitimacies.

Mothers with multiple illegitimacies.


Pharmacological studies of Bulgarian plants with a view to their anticonvulsive effect. Third communication.


Enzymatic studies on the oxidation of sugar and sugar alcohol. II. Purification and properties of NADPH-linked 5-ketofructose reductase.


The role of succinate in the regulation of fatty acid synthesis by heart mitochondria.


A multivariate profile analysis of MMPIs of suicidal and nonsuicidal neuropsychiatric hospital patients.


Effect of epinephrine on human uterine activity in vitro and in vivo.


Survey of mosquitoes in some dairy barns, 1965 to 1966, in Niigata prefecture, Japan.


Illinois State Medical Society.

Illinois State Medical Society.


Alive or dead?

Alive or dead?


Macromolecular changes during the life-span of the mosquito.


The life history of Hepatozoon rarefaciens (Sambon and Seligmann, 1907) from Drymarchon corais (Colubridae), and its experimental transfer to Constrictor constrictor (Boidae).


Is filariasis endemic in the Northern Territory of Australia?


The effects of pipradrol, amylobarbitone, drive and extinction on the relation between Sd intensity and operant response rate.


Aedes aegypti and other mosquitos in relation to the dengue syndrome.


Taxonomy of Aedes aegypti and related species.


Feeding stimuli and artificial feeding.

Feeding stimuli and artificial feeding.


Protective action of ascorbic acid & its precursors on the convulsive & lethal actions of strychnine.


The direct synthesis of phosphoenolpyruvate from pyruvate by Escherichia coli.


The role of lymphocytes in antibody formation. I. Restoration of the haemolysin response in x-irradiated rats with lymphocytes from normal and immunologically tolerant donors.


The role of lymphocytes in antibody formation. II. The influence of lymphocyte migration on the initiation of antibody formation in the isolated, perfused spleen.


Location of a gene specifying phosphopyruvate synthase activity on the genome of Escherichia coli, K12.


Preservation of structure and function of an organized tissue after freezing and thawing.


The effect of positive centrifugal acceleration upon the distribution of ventilation and perfusion within the human lung, and its relation to pulmonary arterial and intraoesophageal pressures.


Direction-of-wording effects in the relationships between scales.


Palmar skin resistance and sweat-gland counts in drug and non-drug states.


The antiphlogistic effects of chloroquine diphosphate and diorotate. I. Anti-acetylcholine, -histamine and -serotonin effects in vitro and in vivo.


An assay for organic phosphorus fractions in microgram quantities of tissue.


Isotopic method for tyrosine transaminase activity.


Hydrogen transfer into mitochondria in the metabolism of ethanol. II. Effect of disulfiram on the hydrogen and energy transfer.


Biosynthesis of methionine in the liver of leukaemic mice.


Using the computerized MMPI.

Using the computerized MMPI.


The effect of aprotic solvents on the adsorption of phenol by alumina.


The possible role of conformational isomerism in the biological actions of acetylcholine: spectral studies.


The autoxidation of sodium salicylate in aqueous solution.


The use of the rabbit ear artery in the bioassay of catecholamines in urine.


Effect of desipramine on the depolarized isolated renal artery.


The preparation of some derivatives of glycyrrhetic acid and oleanolic acid.


The effect of alpha-methyldopa on excretion of noradrenaline metabolites.


Contraction of rat vas deferens by cocaine.


In vitro assessment of anti-inflammatory activity.


The influence of the stability of the amide link on the formation of methemoglobin by anilides.


An insertable orifice tube for in situ contamination counts of solutions in opened ampoules and vials using the Coulter Counter.


Anaphylactic shock and the blood sugar level.


The recognition, distribution and ultrastructure of hydrozoan nerve elements.


A new Maryland record of Thelohania (Nosematidae: Microporidia).


The hypothalamus and liver metabolism.

The hypothalamus and liver metabolism.


The interaction of hexafluorenium with other neuromuscular blocking agents in man.


Dihydrofolic reductase in human blood cells. I. Techniques for the study of enzyme activity and intracellular amethopterin content.


The effect of drug preparation no. 31. on the vegetative nervous system.


Pharmacological assaying of some compounds of the formamidine group.


Viral encephalitis of equines and domestic ruminants in the Near East. II.


Partial resolution of the mixed-function oxidase involved in the cholesterol side-chain cleavage reaction in bovine adrenal mitochondria.


Studies on the mechanism of estrogen biosynthesis. IV. Ovarian metabolism of estr-4-ene-3,17-dione.


Metabolism of [4-14C] testosterone by mouse-liver microsomes.


Prenatal exposure to fluoride.

Prenatal exposure to fluoride.


Pyridine nucleotides in the thyroid gland. 8. Effect of thyroid-stimulating hormone on nicotinic acid-14C incorporation into NAD, NADP and NADPH.


The effect of tyramine on the digital circulation in normotensive and hypertensive subjects.


Enzymes of clostridial purine fermentation. Methylenetetrahydrofolate dehydrogenase.


Gastric absorption of iron.

Gastric absorption of iron.


The incorporation of 18-O into naphthalene in the enzymatic formation of 1,2-dihydronaphthalene-1,2-diol.


Chain elongation of linoleic acid and its inhibition by other fatty acids in vitro.


The measurement of triphosphopyridine nucleotide and reduced triphosphopyridine nucleotide and the role of hemoglobin in producing erroneous triphosphopyridine nucleotide values.


Purification and properties of nicotinamide adenine dinucleotide phosphate-specific benzaldehyde dehydrogenase from Pseudomonas.


Pigeon liver malic enzyme. V. Kinetic studies.


Circadian rhythm in the serotonin content of the rat pineal gland: regulating factors.


Pharmacologic studies with 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid.


Importance of tissue and plasma binding in determining the retention of norchlorcyclizine and norcyclizine in man, dog and rat.


Further studies on the metabolism of drugs by subfractions of  hepatic microsomes. 3. Effects of the NADPH-generating system.


The undescended testis. A morphological and statistical investigation of both testes in uni- and bilateral dystopia.


A further report on the effects of the physician's treating of smoking by placebo.


The influence of 1-hexadecanol on the acid-catalysed hydrolysis of sodium dodecyl sulphate.


The effect of various environmental factors on cocaine and eph edrine toxicity.


The role of the adrenal glands and of alpha- and beta-adrenergic receptors in bronchodilatation of guinea-pig lungs in vivo.


The influence of anaesthetic agents on the formation of methaemoglobin induced by aniline in cats.


Effects of reserpine on the sensitivity of rat isolated uteri preparations to oxytocic drugs.


The antibacterial action of crystal violet.


A method for measurement and statistical analysis of large numbers of experimental tracings.


Micelles as simple models of drug receptors.


Mathematics of three-phase in vitro absorption models.


Ionization constants of cholinesterase-reactivating bispyridinium aldoximes.


Gas chromatography of Indian hemp (Cannabis sativa L.).


Muscle rigidity following administration of succinylcholine.


Effects of ethyl 3-acetamido-4H-pyrrolo[3,4-c]-isoxazole-5(6H)carboxylate on tissue levels of catecholamines and 5-hydroxytryptamine in the rat.


An interaction between the antidepressant drugs desipramine and modaline sulphate.


The assessment of the rate of digestion of serum proteins in mosquito by gel diffusion and immunoelectrophoresis.


Study of the virulence of tick-borne encephalitis virus. VII. Immunogenicity of attenuated virus (clone HY-HK28 "2") for goats, cattle and sheep.


The uptake of amines by human erythrocytes in vitro. 1. Human erythrocytes incubated at 37 degrees C in Krebs bicarbonate solution at pH 7.5 took up 5-hydroxytryptamine, histamine and (-)-noradrenaline at slow rates which were proportional to the concentration of the amines in the medium at least up to 16 mug/ml., in accordance with a simple diffusion process.2. The initial velocity of uptake was greatest for 5-hydroxytryptamine, about 4 times less for histamine and about 20 times less for (-)-noradrenaline; (+)-noradrenaline was not taken up.3. Comparison of uptake measurements by bio-assay and by radioactivity indicated that, after 1 hr, about 10% of each amine taken up had been inactivated.4. At 2 degrees C the uptake of all three amines was greatly diminished. The presence of the antagonists cocaine, chlorpromazine, lysergic acid diethylamide, mepyramine and pronethalol (at 10(-6) or 10(-5) g/ml.) did not affect uptake of the amines.5. In the steady state the ratios of concentration of the amines between cells and medium were greater than could be accounted for by a Donnan distribution.6. Cells which had taken up amines lost most but not all of them into amine-free medium, at rates which were slower than the corresponding rates of uptake. It was concluded that the amines are partially bound in the cells, noradrenaline most and histamine least.7. The slow diffusion of amines into, and the small amounts retained by, erythrocytes indicate that they do not contribute significantly to the rapid termination of the pharmacological actions of these amines in vivo.


Studies on the mechanism of action of mammalian hepatic azoreductase. II. The effects of phenobarbital and 3-methylcholanthrene on carbon monoxide sensitive and insensitive azoreductase activities.


Studies on the mechanism of action of mammalian hepatic azoreductase. I. Azoreductase activity of reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase.


The protective effect of nicotinamide on carbon tetrachloride-induced hepatotoxicity.


The isolation and identification of conoflorin from Tabernaemontana chipii Stapf. H. Huber.


Aromatic amino acid biosynthesis: gene-enzyme relationships in Bacillus subtilis. Single step mutants of Bacillus subtilis which required either one or all of the aromatic amino acids for growth were isolated. The relevant gene defect was determined for each mutant by enzyme assays in vitro. A mutant deficient in each enzyme step of aromatic amino acid biosynthesis was found with the exceptions of the shikimate kinase and the phenylalanine and tyrosine transaminases. Representative mutants carrying the defective genes were mapped by deoxyribonucleic acid mediated transformation by reference to the aromatic amino acid gene (aro) cluster and, alternately, to any of the other unlinked aro genes. The genes coding for dehydroquinate synthetase, 3-enol pyruvylshikimate 5-phosphate synthetase, one form of chorismate mutase, and prephenate dehydrogenase are linked to the aro cluster. Except for the previously identified linkage between the genes of 3-deoxy-d-arabino heptulosonic acid 7-phosphate synthetase and one species of chorismate mutase, the other genes involved in this pathway are neither linked to the aro cluster nor to each other.


Lack of multiplaication of simian virus 40 (SV40) in experimentally infected mosquitoes.


Response of splenectomized mice to bacterial agents.


The new neurology and the biology of emotion: a structural approach.


The partial purification of 17 alpha- and 17 beta-estradiol dehydrogenase activities from chicken liver.


The effects of the administration of sodium benzoate and diethylstilbestrol disulfate on the nepatic levels of several glucocorticoid-sensitive enzymes in adrenalectomized rats.


Studies of the in vitro and in vivo effects of conjugated steroids and carboxylic acids on hepatic tyrosine transaminase in the rat.


Calcium transients in single muscle fibers.


NAD- and NADP-specific dehydrogenases in cord-factor-treated mice.


The dental health of patients presenting with temporomandibular joint dysfunction.


The synthesis of benzimidazole derivatives as potential antihistaminic compounds.


Direct and common connections among identified neurons in Aplysia.


On the disposition of [3H]metaraminol in the rat salivary gland.


Relief of fain in labour. A controlled double-blind trial comparing pethidine and various phenothiazine derivatives.


The effect of reserpine and alpha-methyldopa on the analgesic action of morphine in the mouse.


A quantitative comparison of the antagonism of tubocurarine and diallylnortoxiferine by four anticurare agents.


Carrageenans and the proteolytic activity of human gastric secretion.


The dissolution of aspirin and aspirin tablets.


A note on some changes in the physical properties of Escherichia coli after heat treatment.


The morphology and anatomy of the flowers of Mitragyna ciliata Aubr. et Pellegr. and Mitragyna stipulosa (D.C.) O. Kuntze.


The effect of concentration, time and temperature on the viability of Penicillium notatum spores exposed to phenols.


Production of cardio-active substances by plant tissue cultures and their screening for cardiovascular activity.


Hormonal control of the rat myometrium.

Hormonal control of the rat myometrium.


Nature of adrenergic receptors on the skin melanophores of Rana tigrina.


Simple, sensitive, fluorimetric methods for the estimation of physostigmine in tissue samples and solutions.


Alpha-methyltyrosine: effects on fixed ratio schedules of reinforcement.


Cation dependence of metaraminol retention by rat uterus.


Complexation of penicillins and penicilloic acids by cupric ion.


Blood pressure and noradrenaline levels after treatment with alpha-methyldopa, alpha-methyldopamine and alpha-methyl-m-tyrosine.


Enteral absorption of hyoscine N-butylbromide.


Increased barbiturate sleeping time by simultaneous administration of cardiac glycosides to mice.


Absence of respiratory depression in the new-born rat after maternal administration of etorphine by the sublingual route.


The effect of cryptorchidism, cadmium and anti-spermatogenic drugs on fatty acid composition of rat testis.


Selective protection of 5-hydroxytryptamine stores against the action of reserpine by treatment with 5-hydroxytryptophan.


Attempted induction of implantation in ovariectomized mice with oestradiol and mast cell factors.


Demonstration of antigen on the surface of sensitized rat mast cells.


Meeting of the AMA House of Delegates.

Meeting of the AMA House of Delegates.


General anaesthesia in ophthalmology.

General anaesthesia in ophthalmology.


Folic acid and pregnancy: discussion.

Folic acid and pregnancy: discussion.


Factors stimulating function of lymphaticovenous communications.


The effectiveness of fluoridation in Europe. A review.


Avulsion fracture of the navicular.

Avulsion fracture of the navicular.


The clinical anticariogenic effectiveness of supplementary fluoride-vitamin preparations--results at the end of four years.


Effect of drugs on the accumulation and metabolism of extraneuronal norepinephrine in the rat heart.


The effect of dichloroisoproterenol, pronethalol and propranolol on oxygen consumption in the rat.


The Fourth royal society nuffield Lecture. Decision-making in large organizations.


The Third Royal society nuffield Lecture. Demographic prediction.


The role of the pinna in human localization.


Psychological refractory period and the length of time required to make a decision.


On the sensitivity of frozen micro-organisms to ultraviolet radiation.


On the nature of the lethal and mutagenic action of ultraviolet light on frozen bacteria.


On the evolution of dominance, over-dominance and balanced polymorphism.


Antitoxin against a coelenterate poison.


Delta-5-3-beta-hydroxysteroid dehydrogenase in the ovary of the rhesus monkey.


Histochemical demonstration of oxidative enzymes in the adenohypophysis of the pig, with particular reference to the pars intermedia.


Hexokinase isoenzymes in human erythrocytes. The electrophoretic mobility of hexokinase from human erythrocytes and other tissues was studied with a new method that depends on the fluorescence of reduced nicotinamide-adenine dinucleotide phosphate for detecting enzyme activity on starch gel. The hexokinase of cord-blood erythrocytes has slightly different electrophoretic properties from that of adult red cells. Type I enzyme is split into type I(A) and type I(F); the latter is more intense in cord blood; in hemolyzates of adult blood, the activity of the two bands is usually about equal. No type II enzyme was found in cord blood. The double type I band was present in red cells from adult rabbits.


The prevelance of dental caries in Nigerian populations.


A yellow fever vaccine free from avian leucosis viruses.


Dartos pouch technique orchiopexy.

Dartos pouch technique orchiopexy.


The treatment of brown spider bite.

The treatment of brown spider bite.


Rapidley evolving renal failure in an elderly woman.


Microbial interactions of men and their environment inside a closed system.


Delayed treatment of cryptorchidism with subsequent infertility.


International Lp-workshop.

International Lp-workshop.


Predicting self-assessed social leadership in a new culture with the MMPI.


Influence of carbon tetrachloride on inducible liver enzymes and response to endotoxin in mice. Injection of mice with a sublethal dose of endotoxin 2 hr after administration of 0.1 ml of carbon tetrachloride (CCl(4)) killed 75% of the animals. CCl(4) alone killed no controls. Significant protection against this effect was afforded by 5 mg of cortisone and by 5 mg of nicotinamide adenine dinucleotide (NAD). With a larger dose of endotoxin, cortisone did not give protection. Liver tryptophan pyrrolase activity was lowered 2 hr after CCl(4) injection and reached a minimum after 17 hr. Induction of tryptophan pyrrolase by cortisone, followed by administration of CCl(4), resulted in rapid loss of activity. A significant induction of tyrosine-alpha-ketoglutarate transaminase was observed in CCl(4)-treated mice. The induction of this enzyme by cortisone was somewhat impaired when CCl(4) was administered concurrently with the hormone. CCl(4) did not lower tryptophan pyrrolase in endotoxin-tolerant mice after 4 hr, but at 17 hr the activity was decreased as much as in control mice. Oxidized pyridine nucleotides were decreased 17 hr after administration of CCl(4). This loss was prevented by administration of NAD (5 mg) or by cortisone (5 mg). Carbon clearance from blood was reduced after treatment with CCl(4). These results indicate a degree of similarity between the metabolic effects of endotoxin and CCl(4) in that both depress tryptophan pyrrolase and prevent its induction by cortisone, and both induce tyrosine transaminase in intact mice. Both substances appear to exert these effects through some type of mediated reaction.


Shadow or substance.

Shadow or substance.


Present status of ganglion blocking drugs.


Drug actions on thermoregulatory mechanisms.


Direct antiglobulin (Coombs) reactions in patients with connective tissue diseases.


Surgical preparation of an old traumatic amputation for a foot prosthesis. A case report.


Report of the World Conference on Smoking and Health.


Skin sores and acute glomerulonephritis. The epidemiology of 212 South Carolina cases.


A clinical survey about dental caries, periodontal diseases and oral hygiene in urban population in Iran.


Release of prostaglandin E-1 from the rat stomach.


Metabolism of glucose-1-14C and glucose-6-14C by testis tissue from cryptorchid and testosterone propionate treated rabbits.


Survey of cryo-ophthalmology.

Survey of cryo-ophthalmology.


Effects of hypophysectomy on rat adrenal corticosteroidogenesis in vivo.


The "battered child" and the celiac syndrome.


Massive bilateral adrenal bleeding: five-year review of cases.


Glossary of chromosomal and genetic terms. 3.


New diet 'starves' cancer cells.

New diet 'starves' cancer cells.


Panel discussion on transplantation.

Panel discussion on transplantation.


Chronic disability and the sick role.

Chronic disability and the sick role.


A case report: persistent pulmonary infection with phage-associated mucoid pseudomonad.


Maolate (chlorphenesin carbamate) a new myanalgic drug in industrial medicine.


Medical management of the tension night eater.


The needs of the catholic patient.

The needs of the catholic patient.


Home health services.

Home health services.


Personality determinants of psychophysiological response to stress: a theoretical analysis and an experiment.


Performance under social reinforcement as a function of masculinity--femininity of experimenter and subject.


Anxiety and repression as predictors of the use of incidental cues in problem solving.


Synthesis of ketoximino esters as antihistaminics.


The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy.


The effect of 2,2'-dithiodipyridine on thiols and oxidizable substrates of Ehrlich ascites cells and of normal mouse tissues.


The in vitro inhibition of the N-demethylation of pethidine by phenelzine (Phenethylhydrazine).


Turnover of NAD in bacteria.

Turnover of NAD in bacteria.


Alternative pathways of glucose metabolism in fetal rat brain.


Influence of gonadtrophins on the cholesterol-sidechain cleavage reaction by rat-testis mitochondrial preparations.


Evidence for discrimination against tritium during oxidation of glucose via the glucose-6-phosphate dehydrogenase reaction.


Isolation of 2-(methylamino)ethylphosphonic acid from the proteinaceous residue of a sea anemone.


The effects of diethylcarbamazine treatment on the viability of microfilariae ingested by intermediate hosts.


Paramedian incision for the removal of abdominal testicles in the horse.


Contribution of skeletal muscle to nonshivering thermogenesis in the dog.


Injuries to the lower limb.

Injuries to the lower limb.


Hemodynamic mechanisms of erection in the canine penis.


Sarcomas and multiple polyposis in a kindred. A genetic variety of hereditary polyposis?


Central factor in auditory fatigue--an artifact?


Male-female differences in MMPI ego strength: an artifact.


Relation of sucking strength to personality variables.


Psychotherapeutic persistence.

Psychotherapeutic persistence.


Differences between Negro and white pregnant women on the MMPI.


Relation of mood and hypnotizability: an illustration of the importance of the state versus trait distinction.


Personality characteristics of young male narcotic addicts.


Multivariate analyses of parents' MMPIs based on the psychiatric diagnoses of their children.


Depolarization and excitation-secretion coupling in presynaptic terminals.


Validation attempt of Hovey's five-item MMPI index for CNS disorders.


Glucose entry into the human epidermis. II. The penetration of glucose into the human epidermis in vitro.


A critical study of isocarboxazid (Marplan) in the treatment of depressed patients.


Electrophysiological studies of the action of GABA on the synaptic membrane.


State-dependent learning produced with steroids.


Pharmacology of the mechanism of certain effects of reserpine in the rat.


Ascorbate-supported NADP photoreduction by heated Euglena chloroplasts.


The cinnamic acid 4-hydroxylase of pea seedlings.


Hay fever and allergy in general practice: two antihistamine drugs compared.


Phosphate esters in erythrocytes frozen in DMSO.


Pentose phosphate pathway metabolism by normal and glucose-6-phosphate dehydrogenase-deficient human red cell haemolysates.


The inhibitory effect of histamine on mast cell damage induced by antihistamines.


Aeromedical aspects of the supersonic transport: a review.


Responses of the human body to a known force load during prolonged isolation in the enclosed space.


Energy-linked reactions in photosynthetic bacteria. II. The energy-dependent reduction of oxidized nicotinamide-adenine dinucleotide phosphate by reduced nicotinamide-adenine dinucleotide in chromatophores of Rhodospirillum rubrum.


The metabolism of hydroxychlorpromazines by rat liver microsomes.


The adrenergic neurone blocking action of [2-(methylphenylamino)-ethyl]guanidine sulfate. II.


Effects of ten hours of implosive therapy in the treatment of outpatients: a preliminary report.


Cleft lip and palate in dogs: a progress report.


Development and validation of an MMPI scale of assaultiveness in overcontrolled individuals.


A review of clinical trials utilizing acidulated phosphate-fluoride topical agents.


Mass treatment of children with a stannous fluoride-zirconium silicate self-administered prophylactic paste for partial control of dental caries.


Clinical findings on the effectiveness of stannous fluoride and acid phosphate fluoride as caries reducing agents in children.


Iodine induction of metamorphosis in Aurelia.


Histopathology of intersexuality in mosquitoes.


The effect of antibacterial compounds on the electrical conductance of micellar sodium dodecyl sulphate.


Crystal growth in aqueous suspensions.

Crystal growth in aqueous suspensions.


The effect of ultrasonic energy on the aqueous extraction of senna pericarps.


The effect of particle size on the strength of sodium chloride tablets.


Some effects of ampicillin on growing and glucose-starved cells of Escherichia coli.


Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes.


The absorption and urinary excretion in man of fenfluramine and its main metabolite.


Neuromuscular blocking agents: structural modification of (+)-tubocurarine and (minus)-curarine.


Blood concentrations of pethidine and pentazocine in mother and infant at time of birth.


Surface-active betaines: N-alkyl-NN-dimethylalanine hydrobromides and their critical micelle concentrations.


The ratio of orthogonal function coefficients as an index of purity.


A rapid thin-layer chromatographic method for the determination of noscapine (narcotine) and papaverine in opium and in pharmaceutical preparations.


The gas chromatographic determination of imidazolines in pharmaceutical preparations.


Some factors affecting the sizing and counting of Escherichia coli with the Coulter Counter.


In vitro effects of some chemotherapeutic agents on mycobacteria. Examination of the bactericidal and bacteriostatic effects of nine antibiotics on atypical mycobacteria revealed that streptovaricin complex and streptovaricin C exerted bactericidal effects on several strains in concentrations lower than 1.0 mug/ml. An exposure to the drug for 48 hr at 37 C was necessary to effect a complete inactivation of more than 99.9% of the exposed microorganisms. The appearance of strepto-varicin-resistant mutants was observed. However, these mutants were unstable, and reversion to streptovaricin susceptibility occurred. Celesticetin salicylate, added in a concentration of 100.0 mug/ml to the medium of Olitzki and Gershon inoculated with Mycobacterium leprae, effected a complete change of the uniformly stained mycobacteria to bipolarity, which indicates the devitalization of this microorganism.


Postmortem lung cultures.

Postmortem lung cultures.


Dental status of different age groups in the Usambara Mountains, Tanzania.


Asian Conference on Student Health.

Asian Conference on Student Health.


Genetic recombination in DNA-induced transformation of pneumococcus. V. The sbsence of interference, and evidence for the selective elimination of certain donor sites from the final recombinants.


In vitro activity of doxycycline against bacteria from clinical material. Doxycycline (alpha-6-deoxy-oxytetracycline) was tested against various bacteria of recent clinical origin with 30-mug discs. The antibiotic susceptibility of these bacteria to commonly used antimicrobial agents was also established. Those bacteria which responded with equivocal zones of inhibition about the tetracycline compounds were tested by the tube dilution technique. Staphylococci and enterococci consistently displayed greater in vitro susceptibility to doxycycline than to tetracycline or demethylchlortetracycline.


A special purpose plant environmental chamber for air pollution studies.


Beta adrenergic blockade.

Beta adrenergic blockade.


Effects of some drugs on aggressive behaviour and the electrical activity of the limbic system.


Polyporaceae of Eastern Africa: 1. The genus Favolus Fr.


Preliminary notes on a Simulium survey in the onchocerciasis infested Ulanga district, Tanzania.


Relationship between the contents of virus neutralizing inhibitors and cofactor in the blood and the course of experimental vaccinia infection in rabbits.


Interferon formation in chick embryos infected with one or two viruses.


The temperature requirement for interferon production in cells stimulated by Newcastle disease virus or microbial agents in vitro.


Heterogeneity with respect to s and T50 markers of various measles virus populations, variants of the Edmonston vaccine strain.


Experimental studies with chikungunya virus in Aedes aegypti and Aedes albopictus.


Virus multiplication and carbohydrate oxidative metabolism. I. Effect of succinate dehydrogenase inhibition by malonate on virus multiplication in monkey kidney cell culture.


Multiplication of Tribec virus in chick embryo cell cultures; cytophatic changes and immunofluorescence.


Respiratory syncytial virus infection of diploid cell strains.


The effect of inoculum concentration on virus multiplication in cucumber cotyledons. II. Cucumber mosaic and tobacco mosaic viruses.


An apparently two-factor dose-response dependence in lucerne mosaic virus assay.


On the prophylactic activity on N-methyl isatin beta-thiosemicarbazone against smallpox infection.


Enhancement of tick-borne encephalitis virus plaques in the presence of magnesium chloride.


The effects of amino acids with sulfhydryl groups on herpesviruses in vitro.


Isolation of tick-borne encephalitis virus from the blood of Sorex araneus in a natural focus.


Occurrence of tick-borne encephalitis virus neutralizing antibody in aquatic birds in Central Europe.


Accomplishments of Soviet Virology. (To the 50th anniversary of the Soviet State).


Action of parainfluenza viruses on the mitotic activity of primary trypsinized human embryo kidney cell cultures.


Rapid detection of microorganisms in aerospace water systems.


Oberservations on man in an oxygen-helium environment at 380 mm. Hg total pressure: IV. Communications.


Physical analysis of speech in helium environments.


Evaluation of animals continuously exposed to a 5 psia pure oxygen space cabin atmosphere for eight months.


Effect of inhibitors of nucleic acid synthesis on steroid-mediated induction of tyrosine aminotransferase in hepatoma cell cultures.


Clinical depression and conformity.

Clinical depression and conformity.


Secretion and synthesis of progestins by the luteinized rat ovary in vivo.


Hemodynamics of renal arterial diseases and hypertension.


Analysis of blood. A simplified gas chromatographic approach for toxicologic purposes.


Steroid hydroxylations by guinea-pig adrenal tissue fractions.


Free radicals in NADPH-microsomes-triphenyltetrazolium chloride system as evidenced by initiation of sulfite oxidation.


Chlorophyll a fluorescence and photochemical activities of chloroplast fragments.


Some effects of inorganic phosphate on O2 evolution by isolated chloroplasts.


Nicotinamide-adenine dinucleotide phosphate in gastric mucosa.


The biocleavage of isomeric glyceryl ethers by soluble liver enzymes in a variety of species.


Metabolic adaptations in rat hepatomas: some properties of apo-tryptophan pyrrolase of rat liver and two hepatocellular carcinomas.


Genetics and demography: notes on the third Princeton conference (Princeton, N. J., October 20-22, 1966).


Frequency and content of test items normally omitted from MMPI scales.


The derivation of two distinct anaphylatoxin activities from the third and fifth components of human complement. Anaphylatoxin activity was derived from both human C'5 and C'3 molecules. This was achieved in the case of C'5 by interaction with trypsin or with EAC'4, (oxy)2a, 3. The smooth muscle-contracting material obtained from the treated C'5 was found to be a fragment of approximately 9,000-11,000 molecular weight. Its action was inhibited with antihistamine. The trypsinized C'5 also increased vascular permeability in guinea pig skin. When human C'3 was incubated with C'3 inactivator complex, which consists of a cobra venom protein and a beta-globulin of human serum, anaphylatoxin activity was observed. The activity was associated with a fragment cleaved from the C'3 molecule, having a molecular weight of between 6,000 and 15,000 as determined by gel filtration techniques. Similar activity was derived from C'3 by the C'3-converting enzyme in free or in cell-bound form. The C'5 anaphylatoxin failed to cross-desensitize guinea pig ileum to the contracting capacities of C'3 and guinea pig anaphylatoxin and vice versa. Anaphylatoxin prepared from C'3 by all methods mentioned above caused cross-desensitization to the other C'3 derivatives, but failed to desensitize to guinea pig anaphylatoxin.


Hostility and anxiety indices on the Rorschach content test, hostility guilt index, and the MMPI.


Birth order and personality: some unexpected findings.


Hexafluorodiethyl ether (indoklon) convulsive therapy: a pilot study.


Transformation of cortisone to cortisol in human skin.


MMPI testing for multiple sclerosis.

MMPI testing for multiple sclerosis.


Multiple MMPI profiles of suicidal persons.


Metabolism of ascarosides in the ovaries of Ascaris lumbricoides (Nematoda).


Ionic and osmoregulation in the fresh-water medusa, Craspedacusta sowberyi.


The effect of cholinergic antagonists on the response to acetylcholine, acetyl-beta-methylcholine and nicotine of neurones of Helix aspersa.


Microbiological aspects of space flight.


Impersonal and personal language patterns of repressors and sensitizers.


Aristotle, Linnaeus, and Lewin, or the place of classification in the evaluative-therapeutic process.


Birth order, insolence, socialization, intelligence, and complexity-simplicity preferences.


Social desirability and marital happiness.


Effects of propranolol on the action of neuromuscular blocking drugs.


Heterospecific transformation of pneumococcus and streptococcus. 3. Reduction of linkage.


Blood group specific agglutinins in invertebrates.


Defensive style and esthtic distortion.

Defensive style and esthtic distortion.


Duality of pancreatogenous peptic ulcer.


Effects of prostaglandins on human bronchial muscle.


Effects of noradrenaline and adrenaline on oxygen consumption rate and arterial blood pressure in the newborn pig.


Fate of norepinephrine in sympathetic nerons and by cardiovascular drugs.


Vascular leakage induced by horseradish peroxidase in the rat.


Infection with bacteria, mycoplasma, and viruses in acute respiratory illness.


Personality structure.

Personality structure.


The form of the aldehyde susceptible to enzymic oxidation.


Puriication and some properties of Scenedesmus ferredoxin.


Further studies on the effects of centrophenoxine on the lipofuscin pigment in the neurons of senile guinea pigs.


Is it possible to diagnose inguinal hernia by x-ray? A preliminary report on herniography.


Torsion of an intra-abdominal testicular seminoma.


Distribution of the soluble dehydrogenases and disphorases of Brucei subgroup of trypanosomes in starch-gel electrophoresis.


Depression of myosin B by catecholamine analogs: mechanism and in vivo significance.


17-beta- and 20-alpha-hydroxysteroid dehydrogenase activity in the rabbit.


Space medicine in perspective. A critical review of the manned space program.


Histochemical distribution of some hydroxysteroid dehydrogenases in the placenta, foetal membranes and uterine mucosa of the mouse.


Clinical aspects of commercial aviation medicine.


Seasonal mucopurulent conjunctivitis. Observations on epidemiology in rural areas in summer.


Effects of imipramine on individuals varying in level of depression.


The DuPage County preceptorship program. A pilot program.


Blue Shield urges greater use of private sector in Medicare and Medicaid.


Fixed eruptions due to an ephedrine isomer.


The partnership of the department of public health, medicine, and hospitals in the care of obstetrical and gynecological patients in hospitals.


Alkaptonuria: report of six cases.

Alkaptonuria: report of six cases.


Long term chloramphenicol treatment without bad effect.


Multicentric squamous and basal cell carcinoma of breast simulating Paget's disease.


Human chorionic gonadotropin (HCG) in treatment of obesity.


Arhinencephaly and its clinical significance.


Supracondylar fracture of the humerus in children.


Neonatal streptococcal meningitis.

Neonatal streptococcal meningitis.


Villonodular synovitis.

Villonodular synovitis.


Sacrococcygeal (presacral) teratomas occurring in adult siblings.


The patient with a major acute coronary attack and the role of a coronary care unit.


The Jewish religion.

The Jewish religion.


The clinical effectiveness of stannous hexafluorozirconate as an anticariogenic agent.


The clinical effectiveness of phosphate-enriched breakfast cereals on the incidence of dental caries in adults: results after one year.


What does organizational complexity mean to you?


Social influence on decision-making.

Social influence on decision-making.


Deterrents to developing interest in occupational advancement among nurses.


Administrative factors in nursing that may inhibit job effectiveness.


The shifting frame of reference in nursing administration.


Professionalism and changing concepts of administration.


Personality correlates of withdrawal from smoking.


A comparison of propoxyphene HCl (Darvon) and an analgesic mixture (Percogesic) in pain relief after gingivectomy.


D. pneumoniae. Increased resistance to oxacillin and cloxacillin.


Folic acid activity of human parotid fluid and of mixed submandibular and sublingual fluid.


Antihistamines.

Antihistamines.


Mechanism of enzyme action. 3. Crystallization of the semiquinoid form of D-amino-acid oxidase.


Cryptorchidism and fertility.

Cryptorchidism and fertility.


Respiratory stimulants.

Respiratory stimulants.


Enzymatic properties of Heloderma suspectum venom.


Some characteristics of the rage reaction evoked by chemical stimulation of the hypothalamus.


Problems of the syndrome of familial multiple endocrine adenomas.


Medical education in early Illinois.

Medical education in early Illinois.


Psychotropic drugs: introduction.

Psychotropic drugs: introduction.


Effect of syrosingopine on the acetylcholine content in albino rats.


Treatment of varicose ulcers.

Treatment of varicose ulcers.


Coated vesicles in absorptive cells of Hydra.


Folic acid and pregnancy: discussion.

Folic acid and pregnancy: discussion.


Phylogenetic evolution of the vegatative nervous system.


Active substances in the blood during stimulation of the central vagus nerves.


On the mechanisms of photochemical reductions of FAD and FAD-dependent flavoproteins.


A study of the oral health of Maltese school children.


Studies on streptococcal bacteriophages. II. Adsorption studies on group A and group C streptococcal bacteriophages. Evidence has been presented that Group C bacteriophages differ as to their inactivating site on the streptococcal cell wall. While all three phages adsorb to isolated cell walls, only the C1 phage was inactivated by enzymatically prepared group-specific carbohydrate. None of the Group C phages were inactivated by chemically extracted group-specific carbohydrate. In contrast, all virulent Group A streptococcal bacteriophages adsorbed only to living Group A streptococci. However, Group A temperate phages were able to adsorb to isolated cell walls but not to group-specific carbohydrate. While it has not been possible to identify the specific inactivating substance for the Group A virulent phages, certain pieces of evidence indirectly implicate the group-specific carbohydrate, specifically the N-acetylglucosamine moiety. The fact that Group A virulent phages failed to adsorb to heat-killed Group A streptococcal cells suggests that additional factors produced by the living cell are needed for complete viral inactivation.


Mosquito-borne encephalitis and associated ecologic factors with special reference to the southeastern United States.


Medical education in the service of mankind. Proceedings of the Third World Conference on Medical Education New Delhi, 1966. Final address.


Effect of antibody upon clearance of I-125-labelled pneumococci by the spleen and liver.


The Leeuwenhoek Lecture, 1966. Obligate parasitism in fungi.


The uptake of amino acids by mouse cells (strain LS) during growth in batch culture and chemostat culture: the influence of cell growth rate.


Hypnosis, responsibility, and the boundaries of self.


Stimulus modality and aerophobia: cautions for desensitization therapy.


Host preferences of mosquitoes (Diptera: culicidae) in Suffolk County, New York.


Third World Conference on Medical Education.


Bromism.

Bromism.


Pediatric cardiology (congenital heart disease).


A fresh clinical look at Meniere's disease.


Beal J: Massive intestinal hemorrhage and leiomyoma of small bowel.


The ISMS tax-qualified retirement program. How amended Keogh Act helps physicians.


The physician and the protestant religion.


The United States--tops in research and fifteenth in mortality rate.


Dr. Hopkins, medical society leader, dies.


Evidence for two species of glutamate dehydrogenases in Thiobacillus novellus. When grown autotrophically in a thiosulfate-mineral salts medium, cells of the facultative chemoautotrophic bacterium, Thiobacillus novellus, produced two distinct glutamate dehydrogenases, one specific for nicotinamide adenine dinucleotide phosphate (NADP) and the other specific for nicotinamide adenine dinucleotide (NAD). When glutamate was supplied exogenously as the sole carbon source, the NAD-specific glutamate dehydrogenase was fully induced. Lower levels of the enzyme were found in bacteria grown in l-arginine, l-alanine, glucose, glycerol, lactate, citrate, or succinate. Arginine, histidine, and aspartate, on the other hand, caused a marked repression of the NADP-specific glutamate dehydrogenase activity. The NAD-dependent glutamate dehydrogenase was allosteric. Adenosine-5'-monophosphate and adenosine-5'-diphosphate acted as positive effectors. Both glutamate dehydrogenases were purified about 250-fold and were shown to be distinct protein with different physical properties.


A quantitative method for continuous recording of spontaneous activity in small animals.


Petroleum oils as mosquito larvicides and pupicides. I. Correlation of physicochemical properties with biological activity.


Studies on tetrahydroisoquinolines (THI). I. Bronchodilator activity and structure-activity relationship.


Effect of phenobarbital treatment on the activities of NADPH-dependent enzymes of liver microsomes in fasting or sucrose-fed rats.


Overworked endocrines.

Overworked endocrines.


Comparative effects of imipramine and propranolol on the transmembrane potentials of the isolated rabbit atria.


Clinical and genetic investigation of a large kindred with multiple endocrine adenomatosis.


Effects of angiotensin, bradykinin and oxytocin on electrical and mechanical activities in the taenia coli of the guinea pig.


Dental and oral changes in congenital heart disease.


A Q-sort study of the accuracy of clinical descriptions based on the MMPI.


Urinary and gastrointestinal excretion of metabolites of labelled 5-hydroxytryptamine and 5-hydroxytryptophan.


The role of personality variables in response to chlorpromazine, dextroamphetamine and placebo.


Factors elevating liver tyrosine: 2-oxoglutarate aminotransferase activity in tumor-bearing mice.


Computers and Australian dentistry.

Computers and Australian dentistry.


Geographic tongue.

Geographic tongue.


The Health Evaluation Program at ADA annual sessions.


Scandinavian Symposium in Periodontology 1966.


I.A.D.S. XIVth Congress, Paris, August 1967.


Dental status of mentally retarded children. II. A survey of the prevalence of certain dental conditions in mentally retarded children of Georgia.


Implementing the recommendations of the Conference on Dental Laboratory Relations.


Discussion of questions and proposals from concurrent discussion groups.


2nd International Conference on Oral Surgery. Summary of cyst session.


Organizing a component society officers' conference.


2nd International Congress on Oral Surgery. Conclusions of Chairman.


Post-traumatic arthrosis in the ankle and foot treated with arthrodesis.


Morphological changes in cells of guinea pig testes after infection with Coxiella burneti.


Relation of PLT organisms to the rickettsiae, with special reference to structure and multiplication.


Isolation and characterization of deoxyribonucleic acid from Coxiella burneti.


International symposium on rickettsiae and rickettsial diseases, Smolenice near Bratislava, 26--29 September, 1967. Opening address.


Histochemical and fluorescent antibody studies on the early stages of infection of L cells with Coxiella burneti.


Children's dental health according to educational level of mother.


Biological peculiarities of the development of rickettsiae.


Development of Rickettsia prowazeki in certain species of ixodid ticks.


Multiplication of rickettsiae in tick cells in vitro.


Extracellular development of rickettsiae.


Biochemical and ultrastructural changes in liver endoplasmic reticular fractions during Q-fever.


Complement fixing antigens from Rickettsia quintana.


Study on complement fixing antigens of Rickettsia tsutsugamushi from tissue culture sources.


Studies on antigenic characteristics of Rickettsia tsutsugamushi isolated in the U.S.S.R.


Study of the antigenic structure of Coxiella burneti. VI. Chromatographic analysis of phase I antigen of C. burneti on DEAE-cellulose.


Differentiation of 19S and 7S rickettsial antibodies by passive haemagglutination reaction with cysteine.


An analysis of the immune response to rickettsial antigens in the guinea pig.


Ultrastructure of Rickettsia prowazeki.

Ultrastructure of Rickettsia prowazeki.


Immunological strain differences of bovine tick-borne fever agent.


A new group of rickettsia-like agents recovered from guinea pigs.


The role of viruses, mycoplasmas and bacteria in acute pneumonia in civilian adults.


Modified induction of hepatic tyrosine transaminase in 8-azaguanine-treated rats.


The effect of temperature and some antagonistic drugs on anaphylactic shock in the rat.


Drugs and retrograde amnesia.

Drugs and retrograde amnesia.


A critique of iontophoretic studies of central nervous system neurons.


Behavioral studies of animal vision and drug action.


Stereochemical studies on medicinal agents. V. Synthesis, configuration, and pharmacological activity of pipradrol enantiomers.


Penicillins from 3- and 5-phenylisothiazole-4-carboxylic acids and alkoxy derivatives.


1-Alkyl-1-(2-mercaptoethyl)guanidines and the corresponding thioureas, disulfides, and thiosulfates as antibacterial agents.


Penicillins and cephalosporins from isothiazolylacetic acids.


N-substituted cyclopropylamines as monoamine oxidase inhibitors. Structure-activity relationships. Dopa potentiation in mice and in vitro inhibition of kynuramine oxidation.


The relationship of types of daydream behavior to selected MMPI scales.


The good child facade in chronic underachievers.


Comparative study of EEG effects of antihistamines in normal volunteers.


The biological conversion of 7-dehydrocholesterol into cholesterol and comments on the reduction of double bonds. It is shown that the 7-dehydrocholesterol reductase-catalysed conversion of 7-dehydrocholesterol into cholesterol (II), with a 105000g microsomal pellet of rat liver in the presence of [4-(3)H(2)]NADPH, results in the transfer of radioactivity to the 7alpha-position of cholesterol. When the conversion is carried out in the presence of tritiated water the label is introduced exclusively at the 8beta-position. However, when the conversion of 7-dehydrocholesterol into cholesterol is performed with a 500g supernatant of rat liver homogenate the radioactivity is incorporated at both the 7alpha- and the 8beta-position. Evidence is provided for the presence of an enzyme system in the 500g supernatant that catalyses an equilibration of hydrogen atoms between those at the 4-position of NADPH and those of water. The work with stereospecifically labelled cofactors shows that both the equilibrating system and the 7-dehydrocholesterol reductase utilize the 4B-hydrogen atom of NADPH. In the light of these results a mechanism for the reduction of carbon-carbon double bonds is discussed.


Changes in activity of some enzymes involved in glucose utilization and formation in developing rat liver. 1. The activities of some enzymes involved in both the utilization of glucose (pyruvate kinase, ATP citrate lyase, NADP-specific malate dehydrogenase, glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and NADP-specific isocitrate dehydrogenase, all present in the supernatant fraction of liver homogenates) and the formation of glucose by gluconeogenesis (glucose 6-phosphatase in the whole homogenate and fructose 1,6-diphosphatase, phosphopyruvate carboxylase, NAD-specific malate dehydrogenase and fumarase in the supernatant fraction) have been determined in rat liver around birth and in the postnatal period until the end of weaning. 2. The activities of those enzymes involved in the conversion of glucose into lipid are low during the neonatal period and increase with weaning. NADP-specific malate dehydrogenase first appears and develops at the beginning of the weaning period. 3. The marked increase in cytoplasmic phosphopyruvate carboxylase activity at birth is probably the major factor initiating gluconeogenesis at that time. 4. The results are discussed against the known changes in dietary supplies and the known metabolic patterns during the period of development.


Computer interpretation of personality tests: the automated psychologist.


The metabolism of 5,5'-methylenedisalicylic acid in various species.


Mechanism of amphetamine accumulation in the isolated perfused heart of the rat.


The response of an isolated artery to sympathomimetic amines.


Acetylcarbocholine and acetylsilicocholine: directly or indirectly acting cholinergic spasmogens?


The effects of physiological concentrations of noradrenaline on the coronary resistance of isolated perfused hearts of the cat, dog and monkey.


Subcellular distribution of [3H]-epsilon-aminocaproic acid and its effects on amine storage mechanisms.


Estimation of the stability of dry horse serum cholinesterase by means of an accelerated storage test.


A note on the determination of particle size by dielectric measurement.


The relation between primidone and phenobarbitone blood levels.


The distribution of salicylate in mouse tissues after intraperitoneal injection.


An inverse relationship between the pressor response to noradrenaline and the resting blood pressure.


The influence of hypoxia upon toxicity of a nucleotoxic agent, mustine hydrochloride.


Restraint-induced gastric ulcers in the golden hamster.


Antihistamine constriction in mouse skin microcirculation.


Reciprocal potentiation of neuromuscular blocking agents.


The detection of vocal responses in small laboratory animals.


The self-inhibiting effect of acetanilide on the formation of methaemoglobin.


Endotoxin shock in dogs pretreated with cellulose sulphate, an agent causing partial plasma kininogen depletion.


A new tracheal strip preparation for the evaluation of beta-adrenergic activity.


Activation of Bacillus stearothermophilus spores and release of dipicolinic acid after hydrochloric acid treatment.


Central alveolar hypoventilation during exertion with normal arterial blood gas tensions at rest.


Dehydrogenases in diethylstilbestrol-induced kidney tumors of the Syrian hamster.


Effect of induced cryptorchidism at different weights on performance and carcass traits of lambs.


Effect of epinephrine on permeability to sugar and on the production of free glucose in skeletal muscle.


Biological phase relationships.

Biological phase relationships.


An ounce of hindrance.

An ounce of hindrance.


Poison prevention week.

Poison prevention week.


Popliteal pterygium syndrome . A syndrome comprising cleft lip-palate, popliteal and intercrural pterygia, digital and genital anomalies.


Arbovirus isolations from mosquitoes collected in South Alabama, 1959-1963, and serologic evidence of human infection.


A relationship between rated ability and personality traits in psychotherapists.


Effect of substrate decomposition on the spectrophotometric assay of dihydrofolate reductase.


Semiautomated assay of normal concentrations of urinary glucose by an enzymatic fluorometric technic.


The practice of clinical psychology in the United States.


Relationships between certain personality variables and overinclusion.


The relationship between marital and socioeconomic status and in-patient impairment.


Anxiety and temporal perspective.

Anxiety and temporal perspective.


MMPI characteristics of alcoholic males who are well and poorly adjusted in marriage.


The effect of eliminating offensive items on the reliability and validity of the MMPI.


MMPI response insconsistency of brain-damaged individuals.


International conference on social-psychological research in developing countries.


Human figure drawing indices of sexual maladjustment in male felons.


Self-described depression and scores on the MMPI D scale in normal subjects.


The revised CMM as a test of perceived M-F and of self-report M-F.


Evaluation of methacycline in pneumococcic pneumonia of childhood.


Dental survey in the Brong Ahafo Region of Ghana.


The anatomical site distribution of clinical dental caries in the mandibular incisor teeth of 11- and 12-year-old children. Aetiological implications.


Studies on the role of viruses, bacteria, and M. pneumoniae as causes of lower respiratory tract infections in children.


Effectiveness of debriefing following deception experiments.


Personality, defensiveness, and educational achievement.


Bacon, Harvey and the originators of the Royal Society.


A comparison of chlormezanone, meprobamate, and placebo.


Bibliographies on diseases of medical progress. Antihistamines.


Preparation of native tobacco mosaic virus protein by continuous free-flow electrophoresis.


The subcellular fractions in the biosynthesis of natural compounds. I. Gramine alkaloids.


An automated Minnesota Multiphasic Personality Inventory test.


Sulphasalazine in ulcerative colitis.

Sulphasalazine in ulcerative colitis.


Histology of PCA reactions in guinea pigs. A comparison of reactions produced by guinea pig gamma-G1 and rabbit antibodies.


Stimulus-dependent antagonism of the alpha-methyltyrosine-induced lowering of brain catecholamines by (+)-amphetamine in intact mice.


Intradermal tests with autologous white blood cells in chronic discoid lupus erythematosus and other skin diseases.


Convulsant action of polyphenols.

Convulsant action of polyphenols.


Effects of glucose, pyruvate and alpha-ketoglutarate on acetate metabolism in rat mammary gland.


Determination of sultiam (ospolot) in serum and urine by thin-layer chromatography: serum levels and urinary output in patients under long term treatment.


Mechanism of the respiratory stimulation in saponine-treated leucocytes. The KCN-insensitive oxidation of NADPH.


Photosynthesis by isolated chloroplasts. II. Effects of addition of cofactors and intermediate compounds.


Kilmer Job Corps Center Dental Program.

Kilmer Job Corps Center Dental Program.


Stoicheiometry of the energy-linked nicotinamide nucleotide transhydrogenase reaction in intact rat-liver mitochondria.


REM deprivation. 3. Dreaming and psychosis.


Chlorpromazine-N-oxide formation by subcellular liver fractions.


Effects of drugs on human blood platelet and plasma amine oxidase activity in vitro and in vivo.


Effects of beta-receptor blocking drugs on cardiac metabolism.


Metabolism of neostigmine in vitro.

Metabolism of neostigmine in vitro.


Topical application of drugs to subcortical brain structures and selected aspects of electrical stimulation.


Anesthetic complications in the delivery room.


The short child.

The short child.


Mouse peritoneal cells: their ability to elicit or produce antibody after exposure to antigen.


Psychiatric aspects of hypophyseal stalk section for diabetic retinopathy.


Yeast aldehyde dehydrogenase. II. Properties of the homogeneous enzyme preparations.


Reductase for aromatic aldehydes and ketones. The partial purification and properties of a reduced triphosphopyridine nucleotide-dependent reductase from rabbit kidney cortex.


The effect of pharmacologic agents on salivary secretion and composition in man. I. Pilocarpine, atropine and anticholinesterases.


Alterations in the activities of several rat liver enzymes at various times after the feeding of high carbohydrate diets to rats previously adapted to a high protein regimen.


Effect of phenobarbital and other drugs on the metabolism and uterotropic action of estradiol-17-beta and estrone.


Caries reducing effect of a sodium monofluorophosphate dentifrice.


Adrenoceptive sites in the veins.

Adrenoceptive sites in the veins.


The effect of anti-inflammatory drugs on vascular smooth muscle.


The action of isoprenaline in the depolarized rat uterus.


Nereistoxin and its derivatives, their neuromuscular blocking and convulsive actions.


Performance under sleep loss and fatigue.


Mechanisms of the states of sleep: a neuropharmacological approach.


Identification and quantitation of cortisol metabolites in rat liver homogenate and -slices.


On the morphology and endocrine function of granulosa cells in ovarian follicles and corpora lutea. Biochemical, histochemical, and ultrastructural studies on the  porcine ovary with special reference to steroid hormone synthesis.


Inhibition of initiation of DNA-dependent RNA synthesis by an antibiotic B44p.


Conversion of cholesterol to bile acids in rat: purification and properties of a delta-4-3-ketosteroid 5-beta-reductase and a 3-alpha-hydroxysteroid dehydrogenase.


Role of histamine in hypoxic pulmonary hypertension in the rat. I. Blockade or potentiation of endogenous amines, kinins, and ATP.


Enzymatic conversion of a delta-4-3-ketosteroid into a 3-alpha-hydroxy-5-beta steroid: mechanism and stereochemistry of hydrogen transfer from NADPH. Bile acids and steroids 190.


Studies on the acute inflammatory response. II. Influence of antihistaminics and catecholamines on formaldehyde-induced edema.


Effect of chlorpromazine, dibenamine and phenoxybenzamine on the contractile response of taenia coli to potassium, acetylcholine, angiotensin and barium.


Electrophoretic study of glutathione reductase in human erythrocytes and leucocytes.


The Cheshire cat syndrome.

The Cheshire cat syndrome.


The use of 2,2'-dithiodipyridine in the determination of glutathione and of triphosphopyridine nucleotide by enzymatic cycling.


Free steroid biosynthesis from 5-[4-14C]pregnenolone in normal human adrenal tissue.


Early obstetric practice in Illinois.

Early obstetric practice in Illinois.


Aneurysmosis.

Aneurysmosis.


A study of the effects of Aventyl HCl (nortriptyline hydrochloride) in the treatment of patients with depressive symptoms.


A face saving procedure: marginal resection of the mandible for anterior oral cancer.


Amniocentesis and amniotic fluid analysis in clinical obstetrics.


Erythema nodosum as a manifestation of ulcerative colitis.


Consecutive hydrocephalics.

Consecutive hydrocephalics.


Asthma: a panel discussion.

Asthma: a panel discussion.


Argentaffinoma of the appendix in pregnancy: report of a case.


A virus aetiology for Burkitt's tumour?

A virus aetiology for Burkitt's tumour?


Changes in personality and interpersonal functioning of counselors-in-training.


The effect of selected drugs on the "emotional" behavior elicited via hypothalamic stimulation.


The effects of dependency and self-assertiveness of schizophrenic patients on susceptibility to group influence in perceptual tasks.


The effects of relaxation training and the passage of time on measures of state- and trait-anxiety.


Scoring error on the MMPI.

Scoring error on the MMPI.


On the use of the MMPI with rheumatoid arthritic patients.


Proceedings of the National Conference on Maternal and Child Health, Ottawa, Canada March 19-22, 1967.


Creating the space/terrestrial analog.

Creating the space/terrestrial analog.


Mucous nasal polyps can be managed non-surgically.


Transfer experiments: a plea for tolerance.


Mosquito ecology.

Mosquito ecology.


Alkaline phosphatase and the metabolism of bone tissue.


The evidence in favour of psychotherapy.


Volunteer and nonvolunteer characteristics in an outpatient population.


Desensitization and relaxation in the modification of psychiatric patients' interview behavior.


Patterns of defensive response to threatening stimuli: antecedents and consistency.


Three models of clinical judgment.

Three models of clinical judgment.


On the catalytic mechanism of D-amino-acid oxidase.


Production of antibiotics by Epidermophyton floccosum. I. The antibiotic spectrum of crude filtrate.


Cucurbitacin B delta 23-reductase from Cucurbita maxima. II. Cofactor requirements, enzyme kinetics, substrate specificity and other characteristics.


Studies on tyrosine-alpha-ketoglutarate transaminase from bovine thyroid and liver tissue.


Psychological impact of heart disease in the family of the patient.


Relationship between the molecular conformation of choline aryl ethers and nicotine-like stimulant activity.


Some actions of histamine and 5-hydroxytryptamine on isolated chicken oesophagus.


The isolated hypogastric nerve-vas deferens preparation of the rat.


Selective blockade of adrenoceptive beta receptors in the heart.


Investigation into the mode of action of histamine on the isolated rabbit heart.


Treatment of Gilles de la Tourette's Syndrome with haloperidol.


Immunohistological studies on Crooke cells.


Receptors for noradrenaline and histamine in the rabbit's posterior vena cava.


Psychological and sociological dimensions of anomie in a psychiatric population.


Experimental myocardial necroses and their prevention by drugs.


Involvement of a B-type cytochrome in the assimilatory nitrate reductase of Neurospora crassa.


A second chlorophyll reaction in the electron chain of photosynthesis--registration by the repetitive excitation technique.


Determinants of angina pectoris.

Determinants of angina pectoris.


Winnie flies to Washington.

Winnie flies to Washington.


The dentist goes to Washington.

The dentist goes to Washington.


Lactic acid dehydrogenase (LDH) in the cornea. 3. Further studies on the nature of the enzyme.


Therapeutic side-effects in drug therapy.


Purpose and intent of the Conference on the school dentist.


Synthesis of ribonucleic acid during early estrogen action.


Autoimmunological aspects of cerebral diseases.


Magnesium pemoline: stimulant effects on performance of fatigued subjects.


2nd International Conference on Oral Surgery. Conclusion of Chairman.


Proceedings of the symposium on carbohydrates in relation to nutrition, economic standard and dental caries. General Introduction.


'A.S.M.E.

'A.S.M.E.


Epidemiological and clinical dental findings in relation to intake of carbohydrates.


The microbial content of natural and membrane plaques.


Sleep and psychiatric disorder.

Sleep and psychiatric disorder.


A plea to the dental profession to assist with tooth mortality survey.


The fermentative capabilities of dental plaque.


Conference on prepaid dentistry.

Conference on prepaid dentistry.


Lipodystrophy due to injections.

Lipodystrophy due to injections.


Effect of benzimidazole and kinetin on the nicotinamide nucleotide content of senescing wheat leaves.


Testicular lipids. I. Effects of unilateral cryptorchidism on lipid classes.


Testicular lipids. II. Effect of unilateral cryptorchidism on fatty acids of testicular phospholipids and triglycerides.


Studies on the mechanism of action of thyroid-stimulating hormone.


Nicotinic acid: studies on the mechamism of its antilipolytic action.


Effects of epinephrine on cardiac cyclic 3',5'-AMP, phosphorylase kinase, and phosphorylase.


Virus multiplication and carbohydrate-oxidative metabolism. II. Study on the metabolism of surviving chorioallantoic membrane and on malonate action on its respiration and virus multiplication.


A study on the nature of nucleic acid of arbovirus Tribec.


Immunofluorescent and cytochemical study on tick-borne encephalitis virus-infected cells.


Relationship between group A arbovirus reproduction and cytochemical changes in infected cells.


Development of neutralizing, haemagglutination-inhibiting and strain-specific complement-fixing antibodies in guinea pigs given inactivated influenza vaccine.


Characteristics of various fluorescent antibody techniques used in investigating influenza virus multiplication in chick embryo kidney cell cultures.


Influence of the photodynamic effect on the kinetics of plaque growth of Bacillus subtilis phages SP 3 and SP 8.


Localization of polyoma virus-induced tumour complement-fixing antigen in protein fractions of tumour extracts obtained by gel filtration.


Method for detecting influenza virus sensibilizing antigen by the antibody neutalization test.


Immunodiffusion reaction with influenza virus haemagglutinin.


Inhibition of tobacco mosaic virus infection by coumarin.


A simple method for preparation of complement-fixing Coxiella burneti antigen.


Some physical properties of purified neurotropic foot-and-mouth disease virus.


Cytophotometric determination of RNA contents in HEp-2 cells infected with coxsackievirus B1.


Study on a serum inhibitor to West Nile virus.


Differentiation of coxsackieviruses based on the character of adsorption bentonite.


Inhibitory activity against Japanese encephalitis viral haemagglutination and infectivity of D-mannose-containing polysaccharides.


Thymidine kinase activity in bone marrow cells from chicken infected with myeloblastosis virus.


Mycoplasma pneumoniae pneumonia.

Mycoplasma pneumoniae pneumonia.


Localization of nuclear and cytoplasmic herpes simplex antigens in infected cells by immunofluorescence.


The diagnosis of neck and arm pain by examination.


Control of bacteriuria in geriatric populations.


Report of one case and review of the literature: Ruptured splenic artery aneurysm.


Clinical experience with methacycline in children.


Pre-operative medication with rectal pyrilamine-pentobarbital.


Adult "internal" hydrocephalus.

Adult "internal" hydrocephalus.


Diabetic dermadromes.

Diabetic dermadromes.


A suicide prevention center in Chicago.

A suicide prevention center in Chicago.


Impartial medical testimony.

Impartial medical testimony.


Highly reduced analogues of the pyridine nucleotide coenzymes. Synthesis of tetrahydro- and hexahydronicotinamide adenine dinucleotides and certain of their derivatives.


The synthesis of three fully acetylated aldobiouronic acid methyl esters, including 6-o-(methyl 2,3,4-tri-o-acetyl-alpha-d-glucopyranosyluronate)-tetra-o-acetyl-beta-d-glucopyranose.


The pharmacologic absis for the control of motion sickness by drugs.


Organization of ampullary electric receptors in Gymnotidae (Pisces).


Cellular control of macromolecular synthesis: rates of synthesis of extracellular macromolecules during and after depletion by papain.


Experimenter-subject interaction in verbal conditioning: review of the literature.


Discussion patterns of homogeneous groups of repressers and sensitizers following success and failure.


Rheumatoid arthritis with rheumatoid nodules and allergic granuloatosis.


20-alpha-Hydroxysteroid dehydrogenase and reductive pathways in mouse adrenal glands in vitro.


Determination of initial rates of cortisol 2-alpha- and 6-beta-hydroxylation by hepatic microsomal preparations in guinea pigs: effect of phenobarbital in two genetic types.


Effects of some adrenergic agents on low frequency electroshock seizures.


The MMPI measurement of phenotype anxiety. I. Exploratory study.


Intramitochondrial crystals in Hydra.

Intramitochondrial crystals in Hydra.


The metabolism and excretion of cinnarizine by rats.


On the mechanism of hormone action. VII. Induction by cortisol of a messenger RNA coding for tyrosine-alpha-ketoglutarate transaminase for an in vitro system.


Partial purification of a 10-formyl-tetrahydrofolate: NADP oxidoreductase from mammalian liver.


Isolation and purification of a substance inducing competence and inactivating transforming DNA in Pneumococcus.


The effect of angiotensin on the peristaltic reflex of the isolated guinea-pig ileum.


Metabolism of 11-oxygenated steroids. Metabolism in vitro by preparations of liver. 1. The isolation and partial purification of 11beta-hydroxy steroid dehydrogenase from rat and guinea-pig liver microsomes has been achieved by conventional methods. 2. The efficiency of different 11-oxygenated steroids as substrates has been examined. The relative efficiencies confirm in the main the stereochemical theory of the enzyme-coenzyme-substrate complex that was proposed earlier on the basis of studies in vivo. Delta(4)-3-Ketones and 5alpha-hydrogen steroids are readily metabolized by the enzyme. 5beta-Hydrogen steroids and Delta(4)-3-ketones with certain large alpha-substituents are metabolized to a limited extent or not at all. Halogen substitution in the 9alpha-position enhances the rate of reduction of 11-ketones but blocks the oxidation of the related 11beta-ols. 3. 9alpha-Fluorocortisol is a competitive inhibitor of the oxidation of cortisol, but 9alpha-fluorocortisone is reduced at five to ten times the initial velocity of cortisone. 4. 11beta-Hydroxy steroid dehydrogenase activity has been found in liver microsomes of rat, guinea pig, rabbit and calf. 5. Relative substrate efficiencies and K(m) values are similar in whole (debris-free) homogenates, washed microsomes and acetone-dried powders of washed microsomes. 6. A variety of conditions have been examined for the observation of 11beta-hydroxy steroid dehydrogenase activity. NADP(H) is an efficient and NAD(H) a very poor coenzyme for the reaction.


The pharmacology of acetylcholine-excitation of thalamic neurones.


Isolation of western encephalitis virus from mosquitoes in Alberta.


The hypotensive action of 5-hydroxytryptamine (5-HT) in anaesthetised and pithed rats.


Myocardial and local anesthetic actions of beta-adrenergic receptor blocking drugs: relationship to physicochemical properties.


Effect of N-hydroxyethylpromethazine (Aprobit) on the tissue distribution and excretion of 35S-chlorpromazine in cats.


Amylase activity in black-flies and mosquitoes (Diptera).


Physical and genetic hybrids formed in bacterial transformation.


Ovicidal activity of aliphatic amines and petroleum oil against two species of mosquitoes.


Leary's overt interpersonal behavior: a validation attempt.


Transmission of genetic information during transformation in Diplococcus pneumoniae.


Light-induced electron transefer in Chromatium strain D. 3. Photophosphorylation by Chromatium chromatophores.


Inhibition, by sulphate, of the oxygen evolution associated with photosynthetic carbon assimilation.


A comparison of the separate package and spill-over models of photosynthesis for the alga Chlorella pyrenoidosa.


Flurothyl in mice: seizure, post-convulsive behavior, and interactions with psychotropic drugs.


On the structure and function of reduced nicotinamide adenine dinucleotide phosphate-cytochrome f reductase of spinach chloroplasts.


MMPI findings in field-dependent and field-independent subjects.


Mechanism of the daily rhythm in hepatic tyrosine transaminase activity: role of dietary tryptophan.


Exercise: effects on hexokinase activity in red and white skeletal muscle. Single bouts of exercise increase hexokinase activity in red and white skeletal muscle of guinea pigs. Multiple bouts of exercise cause two-fold increases. In contrast to other enzymes associated with glycolysis, hexokinase activity is higher in red than in white skeletal muscle.


Changes in the level of triphosphopyridine nucleotides during development of sea-urchin eggs (normal and lethal hybrids).


Changes in the activities of enzymes of the biosynthetic pathway of the nicotinamide nucleotides in rat mammary gland during the lactation cycle. 1. The activities of NMN pyrophosphorylase, NMN adenylyltransferase and NAD kinase in the mammary glands of rats at different stages of pregnancy, lactation and involution were measured. 2. NMN pyrophosphorylase has a low activity early in pregnancy, but its activity increases at parturition and in early lactation to reach a maximum at the tenth day of lactation, after which it remains constant until it declines abruptly in involution. 3. NMN adenylyltransferase is already quite active by the tenth day of pregnancy and its activity does not rise further in the second half of gestation. After a sharp rise in activity at parturition, the activity of the enzyme declines slowly throughout the period of lactation and, more sharply, in involution. 4. NAD kinase has a low activity for most of pregnancy, but its activity rises at parturition to a value at 2 days of lactation that is maintained until the tenth day. Between the tenth and fifteenth days of lactation the activity almost doubles, but falls sharply in mammary involution. 5. The relation of the activities of these enzymes to the rates of synthesis of NAD and NADP is discussed.


Teaching of diagnostic radiology in Britain and the United States.


Irreversible effects of formaldehyde on DNA.


Estimating psychological organization, meaning and change in relation to clinical practice.


Polyarteritis nodosa, with an unusual ocular presentation.


Behavioral studies of inhibition and integration in the mosquito Culiseta inornata (Williston).


Osmotic regulation in hydra: sodium and calcium localization and source of electrical potential.


The effect of light and light deprivation upon the ultrastructure of the larval mosquito eye. II. The rhabdom.


Segmentation of teeth.

Segmentation of teeth.


Action of streptomycin on the uterus.

Action of streptomycin on the uterus.


Neuroendocrinology and psychiatry. (A critical assessment of the present status).


Enzymatic reduction of tartrazine by Proteus vulgaris from rats.


The effect of various partial recording methods upon the findings of an incremental caries study.


The effect on dental caries of topically applied acidulated phosphate-fluoride: results after one year.


Effectiveness of epinephrine in local anesthetic solutions on the bacteremia following dental extraction.


Effects of propiomazine hydrochloride on newborn rabbits.


Oxidation of NADPH by polymorphonuclear leucocytes during phagocytosis.


Microbial degradation of corrinoids. VI. Reduction of hydroxocobalamin by cell-free particles from Pseudomonas rubescens. Cell-free particles from Pseudomonas rubescens have been shown to reduce hydroxocobalamin to vitamin B(12r). The particles are unable to reduce the B(12r) to B(12s). The reduction of hydroxocobalamin is dependent upon reduced nicotinamide adenine dinucleotide and is stimulated by flavin adenine dinucleotide. Cobinamide and diaquocobinamide were reduced at 25 and 10%, respectively, of the rate of hydroxocobalamin. Cyanocobalamin, coenzyme B(12), pseudovitamin B(12), and diaquopseudocobalamin were not reduced. Reduced nicotinamide adenine dinucleotide phosphate and flavin mononucleotide were not active. Diaphorase and xanthine oxidase activity were not present in the particulate fraction.


Efficacy of beta-adrenergic blocking agents in inducing histamine sensitivity in mice.


Side-chain scission of cholesterol-4-14C by adrenocortical preincubation media (PIM) and tissue sections.


Isolations of arboviruses in the Lagos area of Nigeria, and a survey of antibodies to them in man and animals.


[General anesthesia with viadril "G" in cases of jaundice and hepatic damage].


Bacterial factors chemotactic for polymorphonuclear leukocytes.


Intake of nucleotides by the mosquito Culsieta inornata in comparison with water, sucrose, and blood.


Acute effects of 3'-methyl-4-dimethylaminoazobenzene intoxication on rat liver. Structural and functional changes in the endoplasmic reticulum and NADPH-related electron transport.


The effect of catecholamines on learning in rats.


Inhibitory of glycine on spinal neurons in the cat.


Evidence favouring the existence of a single adrenergic receptor.


The role of general metabolites in the biosynthesis of natural products. IV. Incorporation of U-14C ribose and U-14C fructose in marrubiin terpene.


An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine.


Relationship between motor changes and pain during esophageal acid perfusion.


Norepinephrine depleting and antihypertensive effect of 4-methoxy-3,5-dihydroxyphenylalanine.


The judicious use of antihistamines.

The judicious use of antihistamines.


8mm film loops: an exciting new media for nursing.


The 8mm film in student and patient education.


Television in nursing education.

Television in nursing education.


Some characteristics of hepatic microsomal systems which metabolize aminopyrine in the rat and rabbit.


Effects of adrenergic blocking agents on lipid mobilization from canine subcutaneous adipose tissue after sympathetic nerve stimulation.


Effects of adrenergic blocking agents on epinephrine- and 3',5'-amp-induced responses in the perfused rat liver.


Myocardial alpha adrenergic receptors and their role in the production of a positive inotropic effect by sympathomimetic agents.


Carcinoma of the testicle.

Carcinoma of the testicle.


Adverse reactions to salicylazosulfapyridine (azulfidine) in the treatment of ulcerative colitis.


Antimicrobial agents and chemotherapy.

Antimicrobial agents and chemotherapy.


The emotional status of cancer patients as measured by a psychological test.


The effects of actinomycin D and aurantin on influenza virus multiplication and virus-induced RNA synthesis in chick embryo cells.


Susceptibility of common pathogenic bacteria to seven tetracycline antibiotics in vitro.


Ophthalmology in Illinois (1818-1968).

Ophthalmology in Illinois (1818-1968).


Further studies on the 11-beta-hydroxylation of deoxycorticosterone and progesterone by rat adrenal mitochondria.


Early obstetric practice in Illinois.

Early obstetric practice in Illinois.


Inhibition of rat liver nicotinamide adenine dinucleotide kinase by reduced nicotinamide adenine dinucleotide phosphate.


Antigen-induced release of slow reacting substance of anaphylaxis (SRS-A rat) in rats prepared with homologous antibody. The polymorphonuclear leukocyte appears to be an essential cellular prerequisite for the antigen-induced release of SRS-A(rat) in the peritoneal cavity of rats prepared with homologous, hyperimmune antisera. Depletion of PMN leukocytes is associated with a marked suppression of SRS-A(rat) release, whereas depletion of circulating lymphocytes or peritoneal mast cells does not influence the antigen-induced release of SRS-A(rat). A local increase in the number of PMN leukocytes produced by the induction of a peritoneal exudate was associated with an enhanced release of SRS-A(rat). A distinct difference in the cellular requirements for the antigen-induced release of histamine and SRS-A(rat) in the rat was observed. Homocytotropic antibody-mediated histamine release could be achieved in leukopenic rats but not in mast cell-depleted animals. Conversely, SRS-A(rat) release was suppressed in leukopenic rats but was unaffected by mast cell depletion. Diethylcarbamazine inhibited the antigen-induced release of SRS-A(rat) following preparation with homologous, hyperimmune antisera but did not interfere with homocytotropic antibody-mediated histamine release. In preventing SRS-A(rat) release, diethylcarbamazine did not interfere with antigen-antibody interaction since desensitization of tissues was possible in the presence of this inhibitor. This observation is consistent with the view that diethylcarbamazine inhibits the reaction sequence leading to the formation and release of SRS-A(rat) at some step subsequent to antigen-antibody interaction. These studies support the view that the immunologic pathways leading to the release of SRS-A(rat) and histamine in the rat are distinctly different in terms of the immunoglobulins involved, the cellular prerequisites, and the effective pharmacologic inhibitors.


The osmotic behavior of digestive cells of Chlorohydra viridissima.


Potentiation of ethanol by Coprinus atramentarius in mice.


The hydrolysis of acetylsalicylic acid by liver microsomes.


Actions of phencyclidine on the perfused rabbit ear.


Inhibition of amine uptake in the mouse heart by some new "thymoleptic" drugs.


Potentiation of acetylcholinesterase by a series of quaternary ammonium compounds.


A note on the subcellular distribution of adipose tissue noradrenaline.


Distribution of acetylcholinesterase, proteolipids and cholinergic receptor in cat brain.


Interactions between monoamine oxidase inhibitors and sympathomimetic amines in the rat isolated vas deferens.


The effect of imipramine on central 5-hydroxytryptamine neurons.


An intravenous catheter for chronic use.


The influence of xanthinol niacinate on ADPand adrenaline-induced platelet aggregation.


Increased uptake of noradrenaline in the rat submaxillary gland during sympathetic nerve stimulation.


Comparison of the effect of various sypathicolytics on thrombocyte aggregation.


Inhibition by disulfiram of the accelerated turnover of catecholamines in the adrenal glands of exercised rats.


Comparison of tolazoline and thymoxamine on skin temperature in man.


The origin of epileptiform seizures caused by oil of Artemisia caerulescens L.


A new principle for the fluorimetric determination of alpha-methylnoradrena-line.


Inhibition of ethanol-induced glycogenolyss in brain and liver by adrenergic beta-blockade.


Effects of diethyldithiocarbamate on the conditioned avoidance response of the rat.


Performance of the Ferranti-Shirley viscometer with automatic flow curve recorder unit.


The assignment of absolute configurations to the individual enantiomorphs of phenylpropylmethylamne and pipradrol hydrochloride.


Mass spectra of derivatives of phenylalkylamines.


Kinetics of buccal absorption of amphetamines.


A note on the absorption of 3-methoxy-N-methylmorphinan hydrochloride from the rat stomach.


Interconversions of mitochondrial pyridine nucleotides. Among the factors that can govern the relative rates of mitochondrial oxidation of isocitrate by means of the isocitrate dehydrogenases linked to diphospho-and triphosphopyridine nucleotides are the intramitochondrial concentrations of these nucleotides. Yeast mitochondria contain enzymes that can alter the ratio of these pyridine nucleotides by interconverting them. A diphosphopyridine nucleotide kinase catalyzes the formation of triphosphopyridine nucleotide from diphosphopyridine nucleotide and adenosine triphosphate; a phosphatase converts triphosphopyridine nucleotide to diphosphopyridine nucleotide. Both reactions are more active with the reduced forms of the pyridine nucleotide coenzymes. These studies suggest that the activity of the mitochondrial triphosphopyridine-nucleotide-linked isocitrate dehydrogenase may be regulated by a cyclic system of pyridine-nucleotide interconversions involving triphosphopyridine nucleotide synthesis and breakdown.


Interrelationships of viral, mycoplasmal, and bacterial agents in uncomplicated pneumonia.


The effect of isoniazid on nicotinamide nucleotide levels in Mycobacterium bovis, strain BCG.


Follicle-stimulating hormone in the pituitary of castrate and cryptorchid parabiotic male rats.


Inhibition of gluconeogenic effects of cortisol by nucleotides and related substances.


Quantitative nitroblue tetrazolium test in chronic granulomatous disease.


The calcium sensitivity of ATPase activity of myofibrils and actomyosins from insect flight and leg muscles.


Inhibition of GSSG reductase by a mixed disulfide complex of CoASSG.


The temperature changes during and after the discharge of the electric organ in Electrophorus electricus.


Electrophysiology and electron-microscopy of rat neuromuscular junctions after nerve degeneration.


Electron resonance studies of haemoglobin derivatives. 3. Line-width and g-value measurements of acid-met myoglobin and of met myoglobin azide derivatives.


Inhibition of the release of slow-reacting substance of anaphylaxis in the rat with diethylcarbamazine.


Pathways in the development of liver macrophages: alternative precursors contained in populations of lymphocytes and bone-marrow cells.


An investigation of the stimulating and mood-elevating properties of pipradol HCl administered to clinically normal volunteers.


Symposium on the mentally ill offender.

Symposium on the mentally ill offender.


Glutamate dehydrogenase activity in Fusarium infected tomato plants.


Carotenogenesis in ripening mangoes.

Carotenogenesis in ripening mangoes.


Histochemical studies of oxidative enzymes in apocrine-like cells of the breast and in axillary apocrine glands.


Modification of laboratory results by partial treatment of bacterial meningitis.


Distribution of staphylococci and microcci among humans and their physical environment during simulated aerospace confinement.


Subjective change with medical student therapists. I. Course of relief in psychoneurotic outpatients.


Otitis media. Clinical observations, microbiology, and evaluation of therapy.


An aggregating immunoglobulin in hyperimmune equine anti-pneumococcal sera.


The psychological effects of 205 hours of sleep deprivation.


Studies in character structure.

Studies in character structure.


Coriolis vestibular stimulation and the influence of different visual surrounds.


Current therapeutics. 243. Niridazole.

Current therapeutics. 243. Niridazole.


Oxygen consumption by fluoride inhibited bat and rat heart homogenates.


Subjective analysis of speech in helium environments.


A partial bacteriological profile of test pilots and their Apollo space vehicle during a simulated fourteen-day lunar flight.


Bacteriology and clinical significance of hemolytic Haemophilus in the throat. Hemolytic Haemophilus are rarely isolated in the clinical laboratory, as they do not grow on sheep or human blood-agar alone. On rabbit blood-agar they grow well and are hemolytic, but they grow less well and are not hemolytic on sheep blood-agar with added X and V factors. A survey was made to determine their incidence in pharyngitis. From 28 of 100 sore throats and from 57 of 100 normal throats, only normal bacterial flora were isolated. beta-Streptococci were present in significant numbers in 9 sore and 11 normal throats; staphylococci in 8 sore and 4 normal throats; pneumococci in 20 sore and 11 normal throats; H. influenzae or H. parainfluenzae in 13 sore and no normal throats; hemolytic Haemophilus in 30 sore and 18 normal throats; enteric bacilli in 1 of each; Candida and Neisseria in 2 sore throats each. All of the 33 hemolytic Haemophilus isolates identified to species were H. parahaemolyticus. All were sensitive in vitro to chloramphenicol, erythromycin, and tetracycline; 30 were sensitive to ampicillin and 30 to penicillin, 26 to novobiocin, and 12 to methicillin. H. influenzae, H. parainfluenzae, and H. haemolyticus are indistinguishable by Gram stain morphology, but H. parahaemolyticus is larger than the other three. Hemolytic and nonhemolytic species are indistinguishable by colonial morphology or by nutritional requirements; only hemolysis gives positive differentiation. Nevertheless, only rarely would this be of clinical importance. H. parahaemolyticus apparently may cause pharyngitis, but it is almost always susceptible to penicillin and rarely if ever causes sequelae.


Penicillin-resistant variants of pneumococci. All of the 74 strains of pneumococci isolated from human infections from 1963 to 1964 proved to be uniformly and highly susceptible to penicillin. Of these strains, 15 were identified by capsule-swelling reactions and were submitted to serial transfer in the presence of increasing concentrations of penicillin. Highly penicillin-resistant mutants were selected from 14 of the 15 strains, whereas one strain was moderately resistant. Of these mutants, 11 could still react with specific antiserum, and all of the mutants could be identified by fermentation reactions and optochin inhibition. The in vitro development of penicillin resistance in these mutants did not result in a change in cell-wall composition sufficient to diminish bile solubility. The possibility of encountering rising penicillin resistance among pneumococci, as well as the possibility that such mutants may react atypically, should be kept in mind.


The electron transport mechanism associated with 12 alpha-hydroxylation of C27 steroids.


The characterization of pneumococcal C-polysaccharide as a ribitol teichoic acid.


Binding of nicotinamide-adenine dinucleotides to diphtheria toxin. 1. Changes in protein fluorescence have been utilized in determining the stoicheiometry and dissociation constants of the complexes of diphtheria toxin with NADH(2), NAD, NADPH(2) and NADP. 2. The binding stoicheiometry is 2moles of NADH(2) and 1mole of NADPH(2)/mole of diphtheria toxin. The binding sites for NADH(2) appear to be equivalent and independent. 3. The toxin shows a higher affinity for the reduced than for the oxidized forms of the nucleotides. 4. Dissociation constants at 0.01I, pH7 and 25 degrees are 0.7x10(-6)m for NADH(2) and 0.45x10(-6)m for NADPH(2). Dissociation constants increase with increasing ionic strength, indicating that the binding is mainly electrostatic. 5. Bound NADH(2) and NADPH(2) may be activated to fluoresce by the transfer of energy from the excited aromatic amino acids of the toxin. Activation and emission spectra of bound and free nucleotides are compared. 6. Since NAD and NADH(2) are cofactors specifically required for the inhibition of protein synthesis by diphtheria toxin, the possible role of toxin-nucleotide complexes is discussed in this regard.


Effect of thyroidectomy on pathways of glucose metabolism in lactating rat mammary gland. 1. Assessment of the overall metabolic changes in lactating mammary gland after thyroidectomy has been made by measurement of the incorporation of (14)C from specifically labelled glucose, pyruvate and acetate into (14)CO(2) and (14)C-labelled lipid in the experimental rats and in sham-operated control animals. 2. Thyroidectomy depressed the oxidation of (14)C-labelled substrates, an effect still apparent when the control rats were pair-fed with thyroidectomized rats; however, the ratio of oxidation of [1-(14)C]glucose/oxidation of [6-(14)C]glucose was unaltered. In parallel with these studies it was revealed that the activities of hexokinase, glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and NADP-linked isocitrate dehydrogenase were all lower in the thyroidectomized group than in the pair-fed control group. 3. Thyroidectomy also lowered the incorporation of (14)C-labelled substrates into (14)C-labelled lipid, an effect further studied by measurement of the activities of citrate-cleavage enzyme and acetate thiokinase. Restricting the food intake of the control rats to that of the thyroidectomized group lowered the activity of citrate-cleavage enzyme, but no further depression was observed on thyroidectomy. The oxidized and reduced nicotinamide nucleotide content of mammary tissue was shown to be decreased in the thyroidectomized rats compared with the control rats.


The equilibrium constants of the glutamate dehydrogenase systems. 1. Equilibrium constants for the oxidation of glutamate by NAD(+) and NADP(+), catalysed by glutamate dehydrogenase, have been measured in phosphate buffers of different ionic strengths and at several temperatures. 2. The equilibrium constants for both systems vary markedly with ionic strength. Thermodynamic values for the two systems obtained by extrapolation to zero ionic strength differ significantly from one another. The standard free-energy change for NADP(+) reduction has been calculated from that for NAD(+) reduction. 3. The heat of reaction has been estimated and is the same with both coenzymes. 4. The thermodynamic data are discussed in relation to earlier data.


The mechanism of the inhibitory action of adrenaline on the mammary gland.


Fatty acid synthesis in intestinal mucosa of guinea pig. 1. Acetate-CoA ligase, acetyl-CoA-carbon dioxide ligase and fatty acid synthetase were shown to be present in particle-free fractions of guinea-pig intestinal mucosa. 2. Each of these enzymes was partially purified by ammonium sulphate precipitation from the particle-free supernatant. 3. The incorporation of acetate and citrate into fatty acid was measured. 4. Gas-liquid radiochromatography was used to investigate the pattern of fatty acids synthesized. 5. The rate-limiting step in fatty acid synthesis was shown to be acetyl-CoA-carbon dioxide ligase.


The relation of neurohumors to autorhythmicity of the isolated ventricle of Strombus gigas (Gastropoda prosobranchia).


The secretion of organic compounds by zooxanthellae isolated from various types of Zoanthus.


Transfer of photosynthetic products from zooxanthellae to coelenterate hosts.


Thin-layer chromatography and U. V. absorption of homeopathic drugs. I. Studies of lpecac mother tincture.


The cholesterol side chain cleavage enzymes in immature rat ovary.


Cocaine-sensitive uptake of sympathomimetic amines in nerve tissue.


Subcellular distribution of some phenothiazines in blood platelets of rabbit.


Effect of desipramine injected intracerebrally in normal or reserpinized rats.


Toxicity of cryoprotective agents at 30 degrees.


The quantiative measurement of motor inco-ordination in naive mice using an acelerating rotarod.


Effect of two non-steroidal anti-inflammatory agents on hexosamine and sialic acid contents of inflamed tissue.


Some aspects of the pharmacology of ibufenac, a non-steroidal anti-inflammatory agent.


Effects of some sympathomimetic amines on the response of the rabbit isolated ear artery to noradrenaline and electrical stimulation.


Modified plethysmometer for measuring foot volume of unanesthetized rats.


Antagonism between calcium ions and some myolytic agents on depolarized guinea-pig taenia coli.


The relation between compression force and dissolution time of tablets.


The influences of drugs on the uptake of 5-hydroxytryptamine by nerve-ending particles of rabbit brain stem.


The effect of diet on blood urea levels in the beagle.


The effect of imipramine, cocaine and neostigmine on the hyperglycaemic response to noradrenaline and adrenaline.


The essential SH-groups in folate reductase.


Genetic heterozygosity in pneumococcal transformation.


Interrelation of stromal NAD(P)ase and human erythrocytic 6-phosphogluconic dehydrogenase.


Statement of the American Orthopsychiatric Association on the work of the Joint Commission on the Mental Health of Children.


Chiasmal arachnoiditis as a manifestation of generalized arachnoiditis in systemic vascular disease. Clinico-pathological report of two cases.


Familial endocrine adenomatosis with associated Zollinger-Ellison syndrome. Wermer's syndrome.


Critical flicker frequency and centrally-acting drugs.


Enzyme activities during the asexual cycle of Neurospora crassa. II. NAD- and NADP-dependent glutamic dehydrogenases and nicotinamide adenine dinucleotidase. Three enzymes, (a) nicotinamide adenine diphosphate-dependent glutamic dehydrogenase (NAD enzyme), (b) nictoinamide adenine triphosphate-dependent glutamic dehydrogenase (NADP enzyme), and (c) nicotinamide-adenine dinucleotidase (NADase), were measured in separate extracts of Neurospora crassa grown in Vogel's medium N and medium N + glutamate. Specific activities and total units per culture of each enzyme were determined at nine separate intervals phased throughout the asexual cycle. The separate dehydrogenases were lowest in the conidia, increased slowly during germination, and increased rapidly during logarithmic mycelial growth. The amounts of these enzymes present during germination were small when compared with those found later during the production of the conidiophores. The NAD enzyme may be necessary for pregermination synthesis. The NADP-enzyme synthesis was associated with the appearance of the germ tube. Although higher levels of the dehydrogenases in the conidiophores resulted in more enzyme being found in the differentiated conidia, the rate of germination was uneffected. The greatest activity for the NADase enzyme was associated with the conidia, early phases of germination, and later production of new conidia. NADase decreased significantly with the onset of logarithmic growth, remained low during the differentiation of conidiophores, and increased considerably as the conidiophores aged.


Studies on the pathogenesis of meningitis. VII. Glucose transport and spinal fluid production in experimental pneumococcal meningitis.


Polyarteritis nodosa. Cases.

Polyarteritis nodosa. Cases.


The effect of diphenoxylate on the peristaltic reflex of the guinea-pig ileum.


The effects of beta-adrenergic receptor blockade on the blood pressure and heart rate changes induced by noradrenaline infusion and postinfusional hypotension.


Announcement of coronary drug project.

Announcement of coronary drug project.


Circular dichroic spectra of D-amino-acid oxidase and its complexes.


Acoustic neuroma, everyone's problem.

Acoustic neuroma, everyone's problem.


New medical communications system being introduced.


VA doubles facilities for treating emphysema.


The relationship of personality and achievement in nursing education, phase II.


Tumor conference.

Tumor conference.


A local community's evaluation of the Dextrostix test and their outlook toward diabetes screening.


Oral diuretics agents.

Oral diuretics agents.


The view box.

The view box.


How long do presidents live.

How long do presidents live.