Mechanisms of reaction of some flavoprotein enzymes with oxygen. Biochemical investigations of the properties of free flavins and of flavoproteins have shown that reduction usually occurs in two stages, with the intermediate formation of semiquinones in the case of free flavins. Flavoproteins often show spectroscopically similar intermediates, when partially reduced with substrate. These may, however, be enzyme-product complexes. Detailed investigation of individual flavoprotein enzymes has shown examples in which catalysis involves transition of the enzyme between oxidized and fully reduced forms (glucose oxidase), between oxidized and intermediate forms (D-amino acid oxidase), and intermediate and fully reduced forms (TPNH-cytochrome c reductase). Further, examples are known in which both intermediate and reduced forms react with oxygen, in which only one reacts, while in TPNH-cytochrome c reductase neither the intermediate nor the reduced form reacts with molecular oxygen. The physiological significance of these complex findings is uncertain, partly because it is not known whether purified flavoproteins occur in the same form in the tissues. It seems unlikely, however, that flavoproteins make a major contribution to the respiratory exchange of mammals.


The mechanism of norepinephrine depletion by reserpine, metaraminol and related agents. The role of monoamine oxidase.


Studies on the biosynthesis of cholesterol. 18. The stereospecificity of mevaldate reductase and the biosynthesis of asymmetrically labelled farnesyl pyrophosphate.


Studies on the biosynthesis of cholesterol. XVII. The asymmetric synthesis of a symmetrical molecule.


Studies on the biosynthesis of cholesterol XIX. Steric course of hydrogen eliminations and of C-C bond formations in squalene biosynthesis.


Dental caries experience in institutionalized mongoloid and nonmongoloid children in North Carolina and Oregon.


Sprouting and degeneration of mammalian motor axons in normal and de-afferentated skeletal muscle.


A quantitative study of the chorioallantoic membrane reaction in the chick embryo.


Enzymatic reduction of non-heme iron protein (adrenodoxin) by reduced nicotinamide adenine dinucleotide phosphate.


Pronethalol for cyanotic attacks.

Pronethalol for cyanotic attacks.


Megacolon, a nonspecific sign: clinical classification and roentgenologic differentiation.


Isolation of two proteins with chloroplast ferredoxin activity from a blue-green alga.


A histochemical study of hamster submandibular lesions.


Synthesis of O-alpha-D-galactopyranosyl-(1--2)-Oalpha-D-glucopyranosyl-(1--1)-D-glycerol, a degradation product of the glycolipid from a pneumococcus.


Adaptive hyperlipogenesis--late 1964 model.


Collagen metabolism.

Collagen metabolism.


Two populations of erythrocytes associated with XX-XY mosaicism.


Quateron--a new remedy for stenocardia.

Quateron--a new remedy for stenocardia.


Polyarteritis nodosum.

Polyarteritis nodosum.


An autopsy case of interstitial pneumonitis with necrotizing pulmonary arteritis.


Additional evidence for the semiquinoid-FAD in d-aminoacid oxidase Michaelis complex crystal.


Symbiosis of hydra and algae. 3. Extracellular products of the algae.


Studies on the metabolism of 5-hydroxytryptamine (serotonin). IV. The effect of various drugs on the in vivo hydroxylation of tryptophan by the brain tissue.


In vitro conversion of 7-3-H-progesterone to androgens by the rat testis during the second half of fetal life.


Histochemical demonstration of the hydroxysteroid oxidoreductases in the umbilical cord and membranes of human term and immature placenta.


The predicament of the aged.

The predicament of the aged.


Benign bronchoesophageal fistula associated with a traction diverticulum of esophagus.


Two foreign bodies of the appendix: a case report.


A method for the histochemical demonstration of triphosphopyridine nucleotide-linked L-hexonate dehydrogenase activity in kidneys of several species.


Liver functions in clinical medicine. I.


Control of gastric hemorrhage with gastric hypothermia.


Variations in dehydrogenase and neotetrazolium reductase (diaphorase) activities in various buffers studied quantitatively in frozen sections.


Preparing a paper on drug therapy: basic principles.


Treatment of hypertension in pregnancy.

Treatment of hypertension in pregnancy.


Absenteeism in industry.

Absenteeism in industry.


Liver functions in clinical medicine.

Liver functions in clinical medicine.


Polyneuropathy due to nitrofurantoin.

Polyneuropathy due to nitrofurantoin.


Sarcoidosis and rheumatoid arthritis.

Sarcoidosis and rheumatoid arthritis.


Non-diabetic ketosis in diabetes during late pregnancy.


Patients refusing psychiatric treatment.


Cytoxan treatment of Kaposi's idiopathic hemorrhagic sarcoma.


Thoughts on psoriasis.

Thoughts on psoriasis.


Paraldehyde acidosis syndrome.

Paraldehyde acidosis syndrome.


A profile of Dr. Hirsch as a humanist.

A profile of Dr. Hirsch as a humanist.


Effectiveness of a stannous fluoride-containing dentifrice in reducing dental caries in children in a boarding school environment.


Familial 2/3 translocation.

Familial 2/3 translocation.


Good general practice without routine screening examinations.


Resistance and immunity in families.

Resistance and immunity in families.


Immunization in general practice.

Immunization in general practice.


The biology of immunity.

The biology of immunity.


What can we prevent in childhood?

What can we prevent in childhood?


Prevention of delinquent and behaviour disorders.


Genesis of mental illness: preventive action which the general practitioner can take.


The case for general screening examinations in middle age.


Screening examinations in old age.

Screening examinations in old age.


Control of chronic disease in general practice and industry.


Influenza and measles vaccines.

Influenza and measles vaccines.


Pharmacological properties of the analeptic compound N,N'-dinitroso-pentamethylene-tetramine (DNPMT).


Tetrahydrofolate dehydrogenase from bakers' yeast.


Necrotizing angiitis. 3. Correlation of clinical findings with biopsy evidence in thirty-one patients.


The liver as the site of C-reactive protein formation. The site of formation of C-reactive protein (CxRP, CRP) has been studied with tissues from rabbits, monkeys, and human beings. Rabbits and monkeys were stimulated to produce the acute phase protein by injection of turpentine, croton oil, endotoxin, paratyphoid-typhoid vaccine, or pneumococci. C(14)-amino acid incorporation in vitro was demonstrated by means of autoradiography of immunoelectrophoretic patterns made with culture fluids. It was found that among many different tissues tested liver was the only tissue which incorporated C(14)-lysine and isoleucine into CxRP or CRP. Only livers taken 16 to 24 hr after various stimuli were active; livers from normal animals or from animals killed 3 to 9 hr after stimulation did not produce detectable amounts of CxRP. Inflamed muscle from the injection site did not show C(14)-amino acid incorporation into CxRP. Several human tissues were also cultured, and a few liver cultures found to contain labeled CRP. The formation of CxRP or CRP by the liver was always accompanied by enhanced C(14)-amino acid incorporation into other serum proteins, but the reverse was not always found.


Development of a computer system for scoring and interpretation of Minnesota Multiphasic Personality Inventories in a medical clinic.


Psychometric evaluations in cardiovascular epidemiology.


Hydrogenase and NADP-reduction reactions by a cell-free preparation of Anabaena cylindrica.


Aging changes in the vascular system of animals.


Antihistamine therapy of burns. Preliminary report.


Clinical and statistical appraisal of seven hundred orchidopexies. Operative technic and follow-up.


Stereochemistry of hydrogen-transfer in the energy-linked pyridine nucleotide transhydrogenase and related reactions.


Comparative study of a fluoride dentifrice containing soluble phosphate and a calcium-free abrasive: second-year report.


Comprehensive field evaluation of the Treatex test.


Observations on a previously undescribed type of cellular degeneration in hydra.


Histopathological changes with age in the flight muscles of the African mosquito, Eretmapodites chrysogaster.


Influence of estradiol on the disposition of chlorpromazine in the rat.


Central nervous system stimulants and pyridoxal phosphate levels in rat brain.


Laboratory transmission of chikungunya virus by Mansonia (Mansonioides) africana (Theobald).


Plasmodium eylesi sp. nov., a tertian malaria parasite from the white-handed gibbon, Hylobates lar.


Clinical management of the patient in shock. Pharmacologic adjuncts to the management of shock.


Template stability of some enzymes in rat liver and hepatoma.


Citrate cleavage in adipose tissue.

Citrate cleavage in adipose tissue.


Effect of variations in protein intake on enzymes of amino acid metabolism.


The metabolism of the retina of the normal and alloxan diabetic rat. The levels of oxidised and reduced pyridine nucleotides and the oxidation of the carbon-1 and carbon-6 of glucose.


Kinetic properties of the TPNH-specific sulfite and hydroxylamine reductase of Salmonella typhimurium.


Substrate-type induction of tyrosine transaminase, illustrating a general adaptive mechanism in animals.


Acute otitis media in children. Bacteriological findings in middle ear fluid obtained by needle aspiration.


The relationship of a measure of self-actualization (POI) to a measure of pathology (MMPI) and to therapeutic growth.


Inhibition of histamine-stimulated gastric secretion by acid in the duodenum in man.


Hydrocortisone stimulation of RNA synthesis in induction of hepatic enzymes.


The regulation of enzyme synthesis by steroid hormones: the role of translation.


Perirenal hematoma secondary to intrarenal microaneurysms of periarteritis nodosa demonstrated radiographically.


A comparison of the effects of amitriptyline and protriptyline on anxiety and depressive states in female prisoners.


The treatment of epilepsy with sulthiame, an interim report.


An evaluation of some possible prognostic indicators of response to phenothiazine treatment of acute schizophrenic psychoses.


Psychological assessment of candidates for a hemodialysis program.


Psychological stress during hemodialysis for chronic renal failure.


The associate degree program graduate in nursing service.


The hospital: a laboratory for the teaching of nursing.


Teaching nursing by television.

Teaching nursing by television.


Utilization of graduates of associate degree nursing programs.


Associate degree nursing education.

Associate degree nursing education.


Clinical-pharmacological testing for parasympatholytic drugs.


Medical problems related to the hostile environment. I. Problems related to closed ecologic systems.


Pathology of the cardiac conduction system in polyarteritis nodosa.


Anesthesia of the rabbit with Equi-Thesin following the administration of preanesthetics.


Effect of carbonylcyanide m-chlorophenylhydrazone on the photochemical reactions of isolated chloroplasts.


Projective drawings of brain-injured subjects.


Light and dark reduction of nitrate in a reconstituted chloroplast system.


Effects of hormone antagonists on morphological and biochemical changes induced by hormonal steroids in the immature rat uterus.


Ovulatory failure in rats after treatment with brain norepinephrine depletors.


The harmful effects of antihistamines.

The harmful effects of antihistamines.


Histological study of functional ectopic pituitary transplants in a teleost fish (Poecilia formosa).


Metabolism of tritiated vitamin D.

Metabolism of tritiated vitamin D.


The action of gamma-rays on deoxyribonucleohistone in solution.


Structure and properties of rat thymus deoxyribonucleoprotein. I. Electric birefringence and centrifugation studies.


The effect of light history on the photolysability of human visual pigments in situ.


Pathogenicity of tick-borne encephalitis virus for the chicken embryo. I. Influence of chicken embryo age and incubation temperature on the lethal activity of the virus.


Characterization of three different lines of a single strain of tick-borne encephalitis virus.


Investigations on the sensitivity to inhibitors of tick-borne encephalitis virus strains.


Cultivation of Tahyna virus in stable cell lines.


Effect of various modes of passaging on the cytopathic activity of Tahyna virus.


Electrophoretic control of influenza A2 virus purification and demonstration of an additional virus-specific electrophoretic component in the purified virus preparations.


Non-specific inhibitors of A2 influenza virus in human sera.


Concerning the nature of the viral neutralizing activity of bovine serum.


Peculiarities of virus multiplication in explants and monolayer cell cultures from immune mouse organs.


Experimental infection of mice with ECHO-6 virus.


Interference between vaccinia and variola viruses in chick embryos.


Nonspecific arboviral haemagglutination inhibitors in hedgehog sera.


A simple method for concentration of pseudorabies virus.


Tahyna virus in foals.

Tahyna virus in foals.


Attempt at inhibiting B virus (herpes virus simiae) growth in rabbits by 5-iodo-2'-deoxyuridine.


Persistent pseudorabies virus infection of primary calf kidney cell cultures.


Identification of lipids in Sd phage particles.


Pharmacologic limitations of analeptic therapy.


Mother and child personality characteristics related to parental marital status in child guidance cases.


Nature of the water-soluble estrogen metabolites formed by rat liver in vitro.


Age and MMPI performance.

Age and MMPI performance.


Stability of new MMPI scales and statistical procedures for evaluating changes and differences in psychiatric patients.


A study of anxiety and academic achievement.


Some characteristics of high- and low-frequency "cannot say" items on the MMPI.


Short-term stability of MMPI profiles.

Short-term stability of MMPI profiles.


The germinal epithelium of cryptorchid testes experimentally induced in prepubertal and adult rats.


The inhibition of respiration and phosphorylation in kidney mitochondria by parathyroid hormone administered in vivo.


A study of gluconeogenesis by the administration of 2-deoxyglucose. II.


Photosensitization of RNA viruses by ethidium chloride.


Study of the virulence of tick-borne encephalitis virus. IV. Thermosensitivity of virions and its relationship to other genetic markers.


Further purification of the receptor for Japanese encephalitis virus.


The role of interferon in tick-borne encephalitis virus-infected L cells. IV. Origin of insusceptibility of persistently infected L cells to the action of exogenous interferon.


The character of haemagglutination inhibiting antibodies against tick-borne encephalitis virus.


Pathogenicity and pathogenesis of Kemerovo virus and Kemerovo virus-like viruses in some laboratory and domestic mammals.


Persistent varicella and herpes simplex virus infection of a continuous monkey kidney cell culture.


Notes on the cultivation of measles virus on chick embryo fibroblast cells.


Interference in tissue cultures induced by rabies virus.


Cytophotometric study on the ribonucleic acid contents of uninfected and poliovirus-infected HEp-2 cells.


Properties of the inhibitors of sunnhemp (Crotalaria juncea L.) mosaic virus in certain plant extracts.


Cultivation of vaccinia virus in tissue culture from the liver of a cold-blooded animal (Lacerta viridis).


Modification of influenza virus morphology by Streptomyces albus G caseinase C.


Reproduction of tick-borne encephalitis virus in a human diploid cell strain.


Periodontal disease, dental caries, oral hygiene and diet in adventist and other teenagers.


Propagation of tick-borne encephalitis virus in human diploid cells.


Use of pig kidney stable cells in experiments on Calovo virus, an arbovirus of the Bunyamvera group.


Effects of pronase on influenza virus.

Effects of pronase on influenza virus.


Comparison of the effect of caseinase C and pronase on the hemagglutinating activity and on the infectivity of Semliki forest virus.


The effect of cortisone on immune reactions in rabies.


Dental caries prevalence in relation to trace elements.


A standardized system of recording dental conditions.


Extraction of receptor preparation for Japanese encephalitis virus from extraneural tissues of the mouse.


The role of interferon in tick-borne encephalitis virus-infected L-cells. 3. The effects of temperature on the production of virus and interferon by L cells during acute and persistent infection.


The effect of colchicine on viral interference and interferon formation.


Cultivation of different viruses in tick tissue cultures.


Study on the adenosine diphosphatase (adenosine triphosphatase) associated with Sendai virus.


Detection of group B arboviruses in chick embryo cell cultures by the fluorescent antibody method.


On the transmission of tick-borne encephalitis virus by fleas.


Tahyna virus in experimentally infected white mice.


Some intratypic differences between haemagglutinating ECHO viruses.


Virus multiplication and interferon formation in lungs from mice infected with A2 influenza virus.


Prophylactic effect of gamma-inhibitor in mice infected with A2 influenza virus.


Interferon-like and antibody-like substances in mouse peritoneal cells stimulated by myxoviruses in vivo.


Virology and the twentieth anniversary of the liberation of Czechoslovakia.


Chemical analysis of permanent and organic gases in a 30-day manned experiment.


Mechanism of barbiturate inhibition on purified flavoenzymes.


Further study on the purification of 3-alpha-hydroxysteroid dehydrogenase of rat liver.


Coenzyme specificity of D-amino acid oxidase for the flavin moiety of FAD.


Some carotenoids in Hydra.

Some carotenoids in Hydra.


Effect of chemical sympathectomy on oxygen consumption by the cold-exposed rat.


Genetics: the centre of science.

Genetics: the centre of science.


Template and stepwise processes in heredity.


Collinearity and the genetic code.

Collinearity and the genetic code.


Genetic transcription.

Genetic transcription.


Genetic organization in higher organisms.


The role of the cytoplasm in heredity.

The role of the cytoplasm in heredity.


Mendel and the study of development.

Mendel and the study of development.


Sex factors and viruses.

Sex factors and viruses.


Fine structure of chromosomes.

Fine structure of chromosomes.


Replication of the bacterial chromosome.


On the association between DNA and membrane in bacteria.


A replicative and synthetic chromosomal unit--the modern concept of the chromomere.


Enzyme polymorphisms in man.

Enzyme polymorphisms in man.


Mendelian and non-Mendelian heredity: a reappraisal.


Somatic mutations and proteins.

Somatic mutations and proteins.


Human chromosomes, normal and aberrant.

Human chromosomes, normal and aberrant.


Variability and selection.

Variability and selection.


Artificial selection in plants and animals.


Genetic polymorphism.

Genetic polymorphism.


Population structure and human evolution.


Drug-induced changes in monoamine levels in the sympathetic adrenergic ganglion cells and terminals. A histochemical study.


On the reacquisition of virulence in trypanosomes of the brucei-group.


Vampire bats as vectors and hosts of equine and bovine trypanosomes.


Studies on the various glands of the tick Haemaphysalis spinigera Neumann 1897.


Quantity and toxicity of Bitis lachesis venom.


Pharmacologic properties of N-oxides of certain antihistaminic drugs.


Magnesium pemoline: enhancement of brain RNA polymerases. The stimulation by magnesium pemoline of systems that synthesize brain nucleic acid was studied in vivo and in vitro. There are differential effects between true RNA polymerase and pseudo-RNA polymerase. The selective stimulation of true RNA polymerase by magnesium pemoline was not observed with stimulants of the central nervous system and psychotropic agents.


Reversible dissociation and association of mammary glucose-6-phosphate dehydrogenase.


Alcohol mixed function. Oxidase activity of mammalian liver microsomes.


The pentose cycle, triose phosphate isomerization, and lipogenesis in rat adipose tissue.


On the therapeutic effect of gamma-inhibitor in mice infected with an inhibitor-sensitive, unadapted A2 influenza virus.


Clinical and psychometric characteristics of the wives of alcoholics.


Providing more meaningful clinical experiences through group or multiple student assignment.


Relationship of a physiological variable to psychiatric diagnoses and personality characteristics.


Sentinels for encephalitis.

Sentinels for encephalitis.


Using the MMPI with adolescents who have somatic symptoms.


Interaction of D-cycloserine with the action of some monoamine oxidase inhibitors.


Oxaloacetic carboxylase in flight musculature of the tsetse fly.


Effect of thyroxine on the level of cytochrome b5 and P450.


The attraction of mosquitoes to hosts.

The attraction of mosquitoes to hosts.


Factors that attract and repel mosquitoes in human skin.


Convulsant properties of allylglycine.

Convulsant properties of allylglycine.


A radio-enzymatic assay for folic acid.

A radio-enzymatic assay for folic acid.


Granulomatous giant-celled angiitis of the central nervous system.


Influence of personality type on drug response.


Newborn girls misdiagnosed as bilaterally cryptorchid males.


Management of emergencies. II. Treatment of acute respiratory failure.


Influence of viadril on the intraocular pressure of rabbits.


Further studies on the effect of calcium ions and corticosteroidogenesis. II. Adrenal mitochondrial swelling by calcium ions.


Tyrosine-alpha-ketoglutarate transaminase. Effect of the administration of sodium benzoate and related compounds on the hepatic enzyme level.


Blinding hysterical blepharospasm treated with pipradrol hydrochloride.


The psychological aspect of gynaecology. The mechanism of neurosis and lucidril therapy.


Occurrence of two intermediates in D-amino acid oxidase reaction.


A convulsant agent for psychiatric use. Flurothyl (Indoklon).


Ipecac syrup in antiemetic ingestion.

Ipecac syrup in antiemetic ingestion.


Spectrophotometric properties of a Triton-clarified steroid 21-hydroxylase system of adrenocortical microsomes.


The carbamate reaction of carbon dioxide with glycyl-glycine.


The kinetics of combination of carbon dioxide with the anions of glycine, glycyl-glycine, and related amino acids.


Structure and properties of rat thymus deoxyribonucleoprotein. II. Effects of enzymes and other agents on electric birefringence properties.


The isolation of thyrocalcitonin and a study of its effects in the rat.


The cytochemistry of the thyroid C cells and their relationship to calcitonin.


The kinetics of action of acetylcholine antagonists in smooth muscle.


A controlled retrospective survey in evaluation of teratogenicity.


The mechanism of inhibition of photosynthesis by high partial pressures of oxygen in Chlorella.


Effect of various types of sympathicolytics on isoproterenol-induced myocardial lesions.


Analysis of the effectiveness of aircraft-disinsection aerosols against resistant houseflies and mosquitos.


Low frequency of co-integration of two linked streptomycin-resistance markers in Pneumococcus.


Increased template activity of liver chromatin, a result of hydrocortisone administration.


Spontaneous alterations in position of the testes.


Effect of vasectomy on psychological functioning.


Trial of bronchodilator drugs given by metered aerosol with a comparison of two bedside methods of estimating airway resistance.


A case of rheumatoid arthritis with polyarteritis demonstrated at the Postgraduate Medical School of London.


Program for Negro physicians on hospital staffs in Chicago.


Maintenance of postoperative electrolyte balance in infants and small children without daily blood analysis.


Progress in peripheral vascular surgery.


"The light here kindled" the story of Oak Forest Hospital.


A Chinese variant of glucose-6-phosphate dehydrogenase.


Reversible dehydrogenation of estrogen triols by soluble preparations of rat and cat erythrocytes.


A preliminary investigation of the pharmacology of longitudinal muscle strips from human isolated jejunum.


Occurrence of anhydrovitamin A and retro-vitamin A in pharmaceuticals; their biological potency and effect on the assay of vitamin A.


Interaction between imipramine-like agents and catecholamine-induced hyperthemia.


Quantitative separation of riboflavine from vitamin mixtures.


Some pyrroline derivatives as potential anti-inflammatory agents.


Effect of choline on the release of acetylcholine and on its tissue stores in the phrenic nerve-diaphragm preparation treated with dyflos.


The effect of humidity and temperature on the equilibrium moisture content of powders.


Pharmacological properties of 3-dimethylamino-2-methyl-1-phenyl-1-o-tolylpropanol (SK&F 70463-A).


Traumatic and endotoxin shock in rats.

Traumatic and endotoxin shock in rats.


Some effects of propranolol on the central nervous system.


Examination of cinnamon by direct thin-layer chromatography.


An improvement on Vane's stomach strip preparation for the assay of 5-hydroxytryptamine.


Autoxidation of linoleic acid.

Autoxidation of linoleic acid.


Effects of the amphetamine group on intraneuronal brain amines in vivo and in vitro.


Inhibition of dopamine-beta-oxidase by diethyldithiocarbamate.


Relation between placebo reactivity and selected personality factors. An exploratory study.


Studies of potential avian, arthropod and mammalian hosts of mosquito-borne arboviruses in the Minnesota area.


The role of temperature and anticoagulant on the in vitro survival of bacterial in blood.


Effect of chronic ethanol ingestion on liver enzyme changes induced by thiamine, riboflavin, pyridoxine, or choline deficiency.


Observations on guinea pig inclusion conjunctivitis agent.


Aspects of drug action: a comparison with intramolecular processes occurring in pharmaceutical and biochemical systems.


Viscosity and stability relations of the system ascorbic acid: water: polysorbate 20.


The compaction of some solid lubricant materials.


An investigation of the pharmacology of macusine B.


Effect of some spasmolytic drugs on the isolated human myometrium.


A new and sensitive bioassay for catecholamines.


Sensitivity of aggressive mice to centrally acting drugs.


The nature of the antagonism of bronchospasm in the guinea-pig by ascorbic acid.


Anorexigenic drugs and lipid mobilisation.


Hydroxymethylation of the benzene ring. 1. Microsomal formation of phenol via prior hydroxymethylation of benzene.


Metabolism in vitro of steroids in the canine ovary.


History and recent reappearance of viruses in the California encephalitis group.


Mosquito transmission of Venezuelan equine encephalomyelitis virus from experimentally infected frogs.


Aruac virus, a new agent isolated from Trinidadian mosquitoes.


Diquat (I,I'-ethylene-2,2'-dipyridylium dibromide) in photo-reactions of isolated chloroplasts.


Mechanism of the reduction of organic nitro compounds by chloroplasts.


Compartmentation and reduction of pyridine nucleotides in relation to photosynthesis.


Studies on the relationship between the transforming activity and the integrity of DNA as revealed by ultraviolet flow dichroism.


Enzyme histochemistry of skeletal muscle. 3. Neurogenic muscular atrophies.


Kinetic parameters for oxygen in reactions involving purified oxidases and tissue slices.


A dental survey among school children in Bayambang, Pangasinan.


The dental health status of the mentally retarded in an institutional population.


Of what value are dental biostatistics to the general practitioner?


Needle introducer for orchiopexy.

Needle introducer for orchiopexy.


The enzymic chain elongation of fatty acids by rat-liver microsomes.


Inhibition of hyperlipogenesis with puromycin or actinomycin D.


An electron microscopic study of cryptorchid and scrotal human testes, with special reference to pubertal maturation.


An evaluation of group psychotherapy--a research report.


The meiotic chromosomes of man.

The meiotic chromosomes of man.


Clinical management of the patient in shock. Neurolept analgesia.


Emotional responses to peptic ulcer management.


Tricarboxylic acid cycle and related enzymes in Hydrogenomonas strain H16G+ grown on various carbon sources.


Different properties of glucose 6-phosphate dehydrogenase from human erythrocytes with normal and abnormal enzyme levels.


A controlled trial of propericiazine and chlorpromazine in "behaviour disorders".


The pharmacological properties of 2,2-bis-(3',4'-dimethoxyphenyl)-N-methyl-N-propargyl ethylamine (BAEA).


Model for the mechanism controlling the expression of competent state in Pneumococcus cultures. Tomasz, Alexander (The Rockefeller University, New York, N.Y.). Model for the mechanism controlling the expression of competent state in pneumococcus cultures. J. Bacteriol. 91:1050-1061. 1966.-The phenotypic expression of competence allowing the cells to absorb genetically active deoxyribonucleic acid molecules from their environment was examined in pneumococcal cultures growing under a variety of environmental conditions. The most important single parameter affecting the time course of this expression process was found to be the cell concentration. Constant high levels of competence could be maintained in cultures growing in a continuous-dilution device. The expression of competence seems to occur through a specific induction process "catalyzed" by a macromolecular cell product-the activator substance. Under most growth conditions, the availability of endogenous activator seems to limit the expression of competence. An "autocatalytic" production of activator ensues during the activation of cells to the competent state. Evidence is presented for physiological influences affecting the cell's capacity to react with the activator. A physiological model is proposed for the control of the competent state in pneumococcus.


Fluoromar. II. Anesthetic for tonsillectomy and adenoidectomy.


Occurrence of streptomycin-dependent mutations in a streptomycin-resistant culture of Diplococcus pneumoniae.


Pneumococcal neuraminidase.

Pneumococcal neuraminidase. Lee, L. T. (Columbia University, New York, N.Y.), and C. Howe. Pneumoccal neuraminidase. J. Bacteriol. 91:1418-1426. 1966.-The elaboration of neuraminidase by pneumococci grown under optimal conditions in liquid medium was studied in relation to the bacterial growth cycle. The enzyme was found free in the culture medium in increasing concentration throughout most of the logarithmic phase of growth, at the end of which enzyme concentration had reached a maximum. Only a small fraction of the total neuraminidase was cell-associated at any time. It appears, therefore, that pneumococcal neuraminidase is actively secreted by dividing cells and does not accumulate solely as a result of cellular autolysis. Neuraminidase in cell-free extracts (types I, III, VII, and XIV) was neutralized both by homotypic and by heterotypic antibody, thus demonstrating it to be a group antigen. The enzyme was separable in agar gel electrophoresis from other protein and polysaccharide pneumococcal antigens. Limited immunochemical data suggest that pneumococcal neuraminidase may be of relatively low molecular weight.


Reconstitution by plastocyanin of the NADP+-photoreducing activity in digitonin fragments of spinach chloroplasts.


An MMPI comparison of two groups of institutionalized delinquents.


Dental health program of the school--city of Gary, Indiana.


Oxidation of the S-methyl group by rat tissue preparations.


Some aspects of drug action: a comparison with intramolecular processes occurring in pharmaceutical and biochemical systems.


Influence of the length of the stimulus period and frequency of sympathetic stimulation on the response of the guinea-pig isolated vas deferens to bretylium, guanethidine and amphetamine.


Urinary excretion kinetics of amphetamine in man.


The anticoagulant activity of carrageenan.


Impairment of sympathetic nerve responses by dopa, dopamine and their alpha-methyl analogues.


Estimation of barbiturates by quantitative thin-layer chromatography.


Comparative toxicity studies at reduced and ambient pressures. I. Acute response.


Synthesis of pyridine-2-sulphonhydrazide 1-oxide and alpha-(2-pyridylthio)acethydrazide and its 1-oxide.


Intraperitoneal ether for anaesthetizing small laboratory animals.


Concentrations of amphetamine in the brain in normal or aggressive mice.


A simplified method for preparing a pithed cat.


Concerning the regulation of some diverse biochemical reactions, underlying the inflammatory response, by salicylic acid, phenylbutazone and other acidic antirheumatic drugs.


Effect of non-steroid anti-inflammatory drugs on aldehyde binding to plasma albumen: a novel in vitro assay for potential anti-inflammatory activity.


The regulatory role of vitamin C on the adrenal function and resistance to histamine aerosol in the scorbutic guinea-pig.


The pharmacology of amygdaloid neurones.


Chronic renal failure and muscle pain in a middle-aged male.


The physiological background--normal and disturbed.


Early pathological changes in chronic bronchitis.


Use of pulmonary tests in general practice.


The recognition of early chronic bronchitis.


Radiological assessment of early bronchitis.


Unanswered questions about chronic bronchitis.


Distribution and incidence of filariae of the genera "Wuchereria" and "Brugia" in the Portuguese overseas territories.


Experience with an anti-smoking clinic.

Experience with an anti-smoking clinic.


Prevention of bronchitis.

Prevention of bronchitis.


The personal doctor's role in prevention.


The natural history of chronic bronchitis.


Isolation by crystallization of fully reduced D-amino acid oxidase.


Polyp hypertrophy as an expression of aging in the colonial marine hydroid Hydractinia echinata.


Optical activity and conformation of carbohydrates. I. Optical rotatory dispersion studies on immunochemically reactive amino sugars and their glycosides, milk oligosaccharides, oligosaccharides of glucose, and blood group substances.


Dihydrofolate reductase from Lactobacillus leichmannii. I. Purification and characterization.


Cytochrome f and plastocyanin: their sequence in the photosynthetic electron transport chain of Chlamydomonas reinhardi.


Repression of enzyme synthesis at the translational level and its hormonal control.


Note on a micromethod for the estimation of ascaridole.


The role of the nervous system in local inflammatory responses.


The significance of an isoprenaline-like metabolite in the interpretation of the responses of blood vessels in skeletal muscle to adrenaline.


The action of sympathomimetic amines on circular and longitudinal smooth muscle from the isolated oesophagus of the guinea-pig.


Macusine B: further pharmacology.

Macusine B: further pharmacology.


The action of arsenic on Bacillus cereus.


On sympathetic regulation of carbohydrate metabolism in the liver.


Preparation and fungicidal properties of (phenylthio)-acetohydroxamic acids and related compounds.


Reactivity of rats to dextran.

Reactivity of rats to dextran.


Effect of metabolic poisons on anaphylactic shock.


An improved method for obtaining twitch responses to acetylcholine in the rat diaphragm.


Effects of certain tranquillisers on the level of homovanillic acid in the corpus striatum.


Reversal by amphetamine of the protective effect of bretylium on reserpine-induced depletion of noradrenaline.


Release of potassium chloride from tablets.


Acutely obstructed incarcerated paraesophageal hiatal hernia.


The paraproteinemias. I.

The paraproteinemias. I.


Home Care Association of St. Clair County.


Depressive anorexia.

Depressive anorexia.


Some thoughts on longevity.

Some thoughts on longevity.


Melanoma masquerading as a psychosomatic disorder.


David Prince, pioneer surgeon.

David Prince, pioneer surgeon.


Results of "Operation Head Start" in Chicago.


Biological activity of phytoestrogens. I. The thyroid uptake of I-131 together with its histology and hormones after beta-sitosterol treatment.


Fluorescence assay of high concentrations of DPNH and TPNH in a spectrophotofluorometer.


Activity of liver tyrosine aminotransferase upon 3-iodotyrosine.


A comparative evaluation of four oral nasal decongestants.


Demefline ('remeflin')--a new respiratory stimulant drug.


Medical problems related to the hostile environment. IV. Problems related to cold.


Effects of two anti-hypertensive drugs.

Effects of two anti-hypertensive drugs.


Toxic liver necrosis.

Toxic liver necrosis.


The isomerization and transesterification of phosphodiester groups in phospholipids.


Metabolism of megestrol acetate and related progesterone analogues by liver preparations in vitro. 1. The rates of metabolism of megestrol acetate, 17alpha-acetoxy-6alpha-methylprogesterone, 6alpha-methylprogesterone, 17alpha-acetoxyprogesterone and progesterone by liver microsome-supernatant fractions from female rats and rabbits have been compared. 2. Introduction of the 6alpha-methyl group into the progesterone molecule markedly decreased the metabolism by liver microsome-supernatant preparations in the rat but not in the rabbit. When 17alpha-acetoxy was the substituting group, metabolism was diminished in the rabbit but not in the rat preparations. Introduction of both the 6alpha-methyl and 17alpha-acetoxy groups into the progesterone molecule markedly decreased the rate of metabolism by liver microsome-supernatant preparations of both species. The Delta(6)-bond in megestrol acetate confers additional resistance to metabolism by rabbit-liver preparations. 3. It is proposed that the observed inhibition of metabolism by these substituents in the progesterone molecule partly or wholly explains the enhanced activity of megestrol acetate.


Studies on the oxidation-reduction systems of the erythrocyte. 1. Starvation for 3 days produces a decrease in methaemoglobin-reductase and glutathione-reductase activities, but it does not alter the glucose 6-phosphate-dehydrogenase activity of the rat erythrocyte. 2. The feeding of a protein-free diet for 11 days causes greater changes in the first two enzymes and also a diminution of the third. Under this experimental condition slight decreases in protein and haemoglobin contents were noted. 3. The experimental animals did not show methaemoglobinaemia, probably because the activity of methaemoglobin diaphorase is preserved. 4. The GSH content was not affected but the stability of the tripeptide in the presence of an oxidizing agent was diminished.


Release of 5-hydroxytryptamine from blood platelets.


Some geometrical considerations concerning the design of tablets.


Pharmacological studies on modaline sulphate (w 3207).


A direct and an indirect action of 5-hydroxytryptamine on the distal part of the isolated colon of the rat.


A comparison of the anti-anaphylactic properties of ethanolamine and hydrocortisone.


Synthesis of 1,3,3-trimethyl- and 1,2,3,3-tetramethyl-5-(methyl- and dimethyl-carbamoyloxy) indolines and their methiodides.


Some tryptamine derivatives: 1-aryloxy-3-[(2-indol-3'-ylethyl)amino]propan-2-ols.


Antitrichomonal activity of 1-[(2,4-dnitropyrryl)-ethyl]-2methyl-5-nitroimidazole and related compounds.


Alkaloids from Mitragyna speciosa (Korth.).


Periodontal health of submarine school candidates: a correlative analysis.


The inhibition of adrenergic alpha-receptors and tryptamine receptors by macusine B.


The preparation of O-methylporphyroxine and its detection in opium.


Evaluation of a pediatric oral antipruritic preparation.


Symptomatic therapy for upper respiratory disorders.


Some pharmacological studies with 14-cinnamoyloxycodeinone.


Depletion of cardiac norepinephrine in the mouse and cat by mercaptoethylguanidine.


Cardiovascular and metabolic effects of cyclic adenosine 3', 5'-monophosphate in unanesthetized dogs.


Mechanism of hypotensive action of mebutamate.


Availability and utilization of dental services by rural Manitoba children.


Propanthelene as an agent for medical vagotomy.


Dental conditions among the inhabitants of Easter Island.


The effect of thioproperazine on the activity of serum catalase in schizophrenic psychoses.


A clinical comparison of prochlorperazine and thioproperazine in psychotic illness.


Endogenous depression as a model for an experimental study of the effect of psychostimulants and thymoleptics.


Changes in enzymes regulating isocitrate breakdown in Neurospora crassa.


Genetic recombination in DNA-induced transformation of Pneumococcus. II. Mapping the amiA region.


"Heat in the body" as a psychiatric symptom: its clinical appraisal and prognostic indication.


Delivery patterns in a real and artificial practice.


An assessment of a new micromethod for determining the erythrocyte sedimentation rate.


Health education about obesity: the results of a two-year follow up.


An epidemiological survey of mental disorders in a community of newcomers to Israel.


Urinary infections.

Urinary infections.


A method for the detection of congenital abnormalities.


A system of recording information in general practice.


Attempted chickenpox prophylaxis with virugon in contacts.


Parazolidin: a new compound analgesic preparation.


The general practitioner bed unit, East Birmingham Hospital.


Ancillary help of the general practitioner in Holland.


Pharmacological study of autonomic innervation of dog retractor penis.


Biological control of mosquitoes: effect of hydra.


Transmural and vagal nerve stimulation of the right atrium of the cat.


Anaesthesia and temperature effect mechanism in neuromuscular blocking by N+ quaternary depolarizing drugs.


An analysis of the opinions toward mental health among nurses and physicians in Dekalb County, Illinois.


Transmission of Guamá and Oriboca viruses by naturally infected mosquitoes.


Dogmatism and psychoneurosis in college women.


Personality similarity and therapeutic success: a failure to replicate.


Studies on the induction, specificity, prevention and breaking of immunologic paralysis and immunity to pneumococcal polysaccharide.


A hemagglutination test and a specific depolymerase for studying immunologic paralysis in mice.


The effect of stress on serum transaminase activity in the rat.


Stimulation of fatty acid biosynthesis by phosphorylated sugars.


Differentiating properties of the dihydrofolate reductases of amethopterin-resistant Streptococcus faecalis/Ak and the sensitive parent strain.


Isolation of Chittoor virus from mosquitoes and demonstration of serological conversions in sera of domestic animals at Manjri, Poona, India.


Studies on the binding and function of flavin phosphates with flavin mononucleotide-dependent enzymes.


Caries incidence in subjects receiving long term antibiotic therapy.


Mechanism of heparin inhibition of adrenal steroid A ring reduction.


Influence of some drugs on toxicity and rate of metabolism of lidocaine and mepivacaine. Experimental study on mice and rats.


Effects of epinephrine and beta adrenergic blocking agents on coronary circulation and myocardial metabolism.


So-called cutaneous polyarteritis nodosa.


Effects of 48/80 on the mechanical properties of the lungs.


A new pattern in medical education.

A new pattern in medical education.


Psychiatric care and the general practitioner.


The quality of medical care.

The quality of medical care.


The modern health service and the nurse.


The ultrastructure of encapsulated Diplococcus pneumoniae type 1 before and after exposure to type specific antibody.


Effect of nicotinamide adenine dinucleotide on the ratio of 17-hydroxycorticosteroids and 17-desoxycorticosteroids synthesized by homogenates of pig adrenal cortex.


Physiologic chemistry of the human oral secretions. Uric acid content of parotid fluid collected without exogenous stimulation. SAM-TR-66-26.


Increased caries resistance associated with higher parotid fluid flow rate. SAM-TR-66-20.


Biosynthesis of capsular polysaccharides in the Pneumococcus.


Somnambulism: psychophysiological correlates. II. Psychiatric interviews, psychological testing, and discussion.


Neuraminidase activity in Diplococcus pneumoniae. Kelly, R. T. (Marquette University School of Medicine, Milwaukee, Wis.), D. Greiff, and S. Farmer. Neuraminidase activity in Diplococcus pneumoniae. J. Bacteriol. 91:601-603. 1966.-A method for the quantitation of neuraminidase in the presence of N-acetylneuraminic acid aldolase is described. The neuraminidase content of Diplococcus pneumoniae was found to be dependent on the media employed for growth; the highest enzyme activity per milligram of bacterial protein was obtained with Todd-Hewitt broth. Neuraminidase production was stimulated in D. pneumoniae by the addition of N-acetylneuraminlactose, N-acetylneuraminic acid, or N-acetylmannosamine to the growth medium. Three rough strains of D. pneumoniae, which were nonpathogenic for mice, lacked neuraminidase activity. Seven of 12 smooth strains contained neuraminidase; enzyme activity was not detected in the remaining 5 smooth strains. There was no correlation between the presence of neuraminidase activity and the capsular type or between neuraminidase production and animal virulence.


Generation of reducing power in chemosynthesis. 3. Energy-linked reduction of pyridine nucleotides in Thiobacillus novellus. Aleem, M. I. H. (Research Institute for Advanced Studies, Baltimore, Md.). Generation of reducing power in chemosynthesis. III. Energy-linked reduction of pyridine nucleotides in Thiobacillus novellus. J. Bacteriol. 91:729-736. 1966.-Cell-free extracts from Thiobacillus novellus. catalyzed an adenosine triphosphate (ATP)-dependent reduction of pyridine nucleotides anaerobically, or aerobically when the respiratory chain was inhibited by azide. The exogenous electron donor employed for the reduction of nicotinamide adenine dinucleotide or nicotinamide adenine dinucleotide phosphate (NADP) was thiosulfate, formate, or mammalian ferrocytochrome c. In the latter case, the oxidation of ferrocytochrome c was observed with the concomitant reduction of the pyridine nucleotide. Values calculated for the molar ratios of ATP utilized-NADP reduced and of cytochrome c oxidized-NADP reduced were 1:1 and 2:1, respectively. The energy-dependent reduction of the pyridine nucleotides was inhibited by Atabrine or amytal and by low concentrations of the uncouplers of oxidative phosphorylation such as 2,4-dinitrophenol and carbonyl cyanide m-chlorophenyl hydrazone. Evidence is presented showing that the reduced pyridine nucleotides are essential for providing the reducing power for the energy-dependent reduction of carbon dioxide in T. novellus.


Syndrome of intestinal arterial insufficiency ("abdominal angina").


Nutritive phagocytosis in animal cells. An electron microscopical study of the gastroderm of the hydroid Clava squamata Müll.


Teratogenic effect of buclizine and hydroxyzine in the rat and chlorcyclizine in the mouse.


Protracted pressor response to angiotensin after bilateral nephrectomy in rats.


Studies on dihydrofolic reductase. I. Purification and properties of dihydrofolic reductase from chicken liver.


Effect of certain drugs on perfused human placenta. V. Use of alpha and beta adrenergic blocking agents to determine the specific effector site of vasoactive substances.


Hepatic glycogen concentration and hexobarbital-sleeping time in mice.


Response of rat thyroid oxidative enzymes to TSH.


Effect of thyrotropin injection on pyridine nucleotide content of thyroid in normal and hypophysectomized rat.


Effects of actinomycin D on ACTH-induced corticosteroidogenesis.


Relation of the testis to adrenal enzyme activity and adrenal corticosterone production in the rat.


Histochemical demonstration of 3-alpha-hydroxysteroid dehydrogenase activity.


Influence of luteinizing hormone on corpus luteum metabolism and progesterone biosynthesis throughout the bovine estrous cycle.


Polyangitis in allergic conditions.

Polyangitis in allergic conditions.


Carcinogenicity of "Alderlin" (pronethalol) in mice.


An evaluation of the histochemical demonstration of certain pyridine nucleotide-linked dehydrogenases.


Oxidative phosphorylation in normal and failure liver, kidney and heart mitochondria.


Observations on man in an oxygen-helium environment at 380 mm. Hg total pressure. I. Clinical.


Observations on man in an oxygen-helium environment at 380 mm. Hg total pressure. II. Respiratory.


Observations on man in an oxygen-helium environment at 380 mm. Hg total pressure. 3. Heat exchange.


Selective brain monoamine oxidase inhibition resulting from an interaction between reversible and irreversible inhibitors.


The effects of arecoline on spinal reflexes of the cat.


Chemical structure and pharmacological activity of glycine derivatives. Influence of disubstitution of the amine function of glycine esters and hydrazides.


Ipecac syrup. Its use as an emetic in poison control.


Psychiatric symptomatology in functional dysphonia and aphonia.


Evaluation of a program for distribution of ipecac syrup for the emergency home management of poison ingestions.


Variations of glycolytic intermediates, phosphate compounds and pyridine nucleotides after prolonged stimulation of an isolated crustacean neurone.


The MMPI and prognosis in stuttering therapy.


Algal bioregenerative systems. Sam-TR-66-11.


Circadian changes in the inhibitory effects of an antihistaminic drug in man.


Antihistamines in the management of allergic conditions.


Histochemical evaluation of enzymatic activities in pleomorphic salivary adenoma.


Effects of a combination of chlorcyclizine hydrochloride and cinnarizine on the linear acceleration test.


Haemodynamic changes induced by intra-arterial injections of vasodilator substances in the muscle circulation of the dog limb with experimental femoral artery occlusion.


Aromatic metabolism in plants. I. A study of the prephenate dehydrogenase from bean plants.


The determination of free epsilon-amino groups in proteins.


The effects of pheniprazine on visual imagery in perceptual deprivation.


Production and utilization of reduced nicotinamide adenine dinucleotide phosphate in the mouse testis.


Effect of rat mobilization on liver acetate metabolism.


Growth and differentiation in Hydra. I. The effect of temperature on sexual differentiation in Hydra littoralis.


The localization of alpha-hydroxy acid oxidase in renal microbodies.


Glucose metabolism and chick neurogenesis. I. Glucose-6-phosphate dehydrogenase activity in the embryonic brachial spinal cord.


An improved method for determining ammonia formed in enzyme reactions.


A new analeptic agent: doxapram hydrochloride (Dopram).


Criteria for thermal regulation for manned spacecraft cabins. NASA Techn Note NASA TN D-3349.


The circus movement (entrapped circuit wave) hypothesis and atrial flutter.


Comparison of weight losses with three reducing regimens--diet therapy, phenmetrazine, and an amphetamine combination (obetrol).


Hope for the senile? Memory drug tests are "encouraging".


Effect of gastrin on isolated smooth muscle preparation.


Enzyme regulatory mechanisms at the level of lactate-oxidoreductase in erythrocytes and ascites tumour cells.


Dependence of photophosphorylation by isolated chloroplasts on the oxidation-reduction state of N-methylphenazinium methyl sulphate (phenazine methosulphate).


A central action of hemicholinium.

A central action of hemicholinium.


Maturation of a stress-activated mechanism inhibiting induction of tyrosine transaminase. Rats of various ages were subjected to the stress of 30 minutes on a noisy reciprocating shaker 4 hours before their liver tyrosine transaminase and tryptophan pyrrolase activities were measured. Adrenalectomized infants and adults and hypophysectomized adults were also stressed. Intact, stressed infants exhibited an increase in tyrosine transaminase activity, while intact, stressed adults showed no change. In the stressed adrenalectomized adult, tyrosine transaminase activity markedly decreased, while adrenalectomized infants showed no change. Hypophysectomy largely, but not completely, abolished inhibition in the adults. Tryptophan pyrrolase activity, when present, was increased by stress in all age groups, but the increase was abolished by adrenalectomy and hypophysectomy. The results suggest stress-activation of a pituitary mechanism that inhibits or represses activation of tyrosine transaminase and that may not function during early postnatal life.


Studies on the demethylation of puromycin and related compounds by liver microsomal enzymes.


Sex-contingent differences between male and female alcoholics.


Family diagnosis: MMPI and CTP results.

Family diagnosis: MMPI and CTP results.


Physique and obstreperous behavior.

Physique and obstreperous behavior.


The relationship of the Edwards personal preference schedule to the MMPI in a patient population.


Stability of MMPI profiles of female psychiatric inpatients.


The MMPI K scale as a predictor of prognosis.


The L scale of the MMPI as an index of falsification.


Correlation of women's MF scores on the MMPI and strong VIB.


The "yell fire" response as an indicator of impaired impulse control.


Linear discriminant function classification of accepted and rejected adoptive applicants.


Structure-disrupting ions: detection of qualitative change in an enzyme. Preparations of erythrocyte glucose-6-phosphate dehydrogenase from normal individuals show similar degrees of inhibition by neutral salts. Preparations from Caucasian subjects with different hereditary deficiency syndromes differ from each other and from normal subjects, indicating a qualitative difference in these specific "deficient" enzymes. Sensitivity to neutral salts may be a means of detecting an amino acid substitution.


The role of mesoglea in mass cell movement in Hydra.


On the role of acetylcholine in regulating the rate of the early chick embryo heart.


The electrically stimulated ileum of the guinea-pig for measuring acetylcholine antagonism at different sites.


Viscosity of phosphatidylcholine (lecithin).


Further effects of imipramine and its desmethyl derivative on the hypothermia induced by reserpine.


The rigidity of gelatin-glycerin gels.

The rigidity of gelatin-glycerin gels.


Anticurare activity of tacrine (THA) in vitro.


The pharmacology of 2-amino-4-methyl-6-phenyl-amino-1,3,5-triazine, a centrally acting muscle relaxant.


Some aggregation effects observed with an emulsion dispersed in saline containing cetrimide.


Enlargement of salivary glands in rats after chronic administration of physalaemin or isoprenaline.


Central nervous system effects of four beta-adrenergic receptor blocking agents.


Effect of high pressure oxygen on the duration of anaesthesia in mice.


Effect of reserpine on the histaminolytic activity of guinea-pig liver.


In vivo inhibition of 3H-noradrenaline uptake by mouse brain slices in vitro.


The limit of sensitivity of bioassay of catecholamines on the perfused arterial segment.


The effect of ascorbic acid on anaphylactic shock in dogs.


Adrenergic mediation in the antagonism between desipramine and reserpine.


Metabolism of drugs and carcinogens by human liver enzymes.


Mechanisms involved in ganglionic blockade induced by tetramethylammonium.


Sympathetic vasodilatation in the dog's paw.


Dependence of hemicholinium action on calcium concentration.


Some differences in uveal reactions between cats and rabbits. 1. Miosis was observed after enucleation in unopened eyes from normal or atropinized, atropinesterase-free rabbits. Such a phenomenon was not seen in enucleated cat eyes, in which the pupils remained widely dilated, whether atropine had been administered or not.2. Pre-treatment of the animals with reserpine did not alter this difference between the species.3. The difference does not appear to be due to absence of irins from the cat iris, since aqueous extracts of cat irides contained a smooth-muscle-contracting activity (cat irin) extractable into ether at pH 3 and therefore consisting of lipid acid(s).4. The difference is not due to insensitivity of the cat sphincter pupillae muscle to irins, since injections of ether-purified cat or rabbit irins into the anterior chamber of enucleated cat eyes kept at room temperature constricted the pupil; injections of histamine were ineffective.5. In experiments on animals treated with atropine +/- mepyramine I.V., photographic measurements revealed a further difference, namely in the speed of miosis after stroking the iris in vivo. The response started later in the cat, and developed more slowly, but often to a fuller extent than in the rabbit.6. In a proportion of cat eyes there was little or no change in intraocular pressure after irritation of the iris adequate to induce maximum pupillary constriction; this was so whether mepyramine had been administered or not.7. Possible reasons for the above species differences are discussed.


On diagnosing diabetes.

On diagnosing diabetes.


Cardiovascular responses to epinephrine during acute hypercapnia in dogs: effects of autonomic blocking drugs.


The natural history of testicular descent and maldescent.


Intestinal propulsion in restrained and unrestrained rats.


Anticoagulant from the sea anemone Rhodactis howesii.


The influence of manned space flight on cardiovascular function.


Errors, reversals, and questionable dental caries diagnoses based on a longitudinal study in children.


The effect of thiols and ganglioside on the alterations in water, sodium and potassium distribution produced in brain slices by vasopressin and protamine.


Combination effect of competitive ganglion block agents on the nicotine-induced ganglion blockade in the cat superior cervical ganglion.


Effects of dimorpholamine on blood pressure.


Cord dissector for orchiopexy: a new instrument.


Current personality assessment research.


Psychological and aptitude issues in career choice and vocational development.


Dental caries incidence in North and South Dakota Indian school children during 30 years.


Fluoridation and the Philadelphia story.


Stimulation of the utilization of 1-14C-glucose in chicken red blood cells infected with Plasmodium gallinaceum.


Isolation and characterization of arboviruses from Almirante, Republic of Panama.


An ecological survey for arboviruses in Almirante, Panama, 1959-1962.


Early human myocardial infarction. A histochemical study.


Electrophysiologic analysis of the site of action of doxapram hydrochloride.


Storage and synthesis of norepinephrine in the reserpine-treated rat brain.


Comparison of the stimulating effects of nicotine, pilocarpine and histamine on the superior cervical ganglion of the cat.


The adrenergic blocking activity of N-tert.-butylmethoxamine (butoxamine).


Psychological factors in cardiac patients. Distortion of clinical recommendations.


Symposium of gastroenterology.

Symposium of gastroenterology.


The retractile testis.

The retractile testis.


Release of acetylcholine by tyramine.

Release of acetylcholine by tyramine.


Antihistaminase activity of some alkaloids of Rauwolfia serpentina and their derivatives.


Autonomic regulation of arterial pressure responses.


On the pharmacology of syrosingopine and reserpine.


Observations on the antagonism of intravenous histamine in the guinea pig by 1-[(3-indolyl)alkyl]-4-arylpiperazines.


Adrenergic receptors in the progesterone dominated rabbit uterus.


Hypnotic-analeptic interaction at different neural levels in cats and rabbits.


Immunochemical studies on some immune systems involving beta-(1,4) linked glucose.


Effect of splenectomy on the susceptibility of mice inoculated with Diplococcus pneumoniae. An experimental model is described which demonstrated increased susceptibility of mice to infection with D. pneumoniae following splenectomy. It was necessary to use small numbers of a particular strain of pneumococcus (D. pneumoniae type 6), intravenous infection and a particular strain of mouse (pathogen-free NCS strain). The increase in susceptibility persisted for at least 4 months after splenectomy. With modifications in experimental design such as use of large numbers of organisms, a different strain of pneumococcus, the intraperitoneal route of infection or a different mouse strain no increase or a much less impressive increase in susceptibility was demonstrated. Following intravenous injection of small numbers of D. pneumoniae Type 6 bacteremia tended to persist in all NCS mice. Multiplication of pneumococci subsequently occurred in a higher proportion of mice with splenectomy and at a more rapid rate than in control animals. Mice with splenectomy usually had more D. pneumoniae per ml of blood than per gram of any tissue. This suggested that in these mice multiplication of microorganisms occurs primarily in blood. In control mice higher concentrations of bacteria were present in spleen than in blood, and higher concentrations were found in blood than in other tissues. These results suggested that in normal mice infected intravenously with small numbers of D. pneumoniae Type 6, the spleen protects by removing and killing small but critical numbers of D. pneumoniae which are circulating in the blood. No evidence was found to suggest that the altered susceptibility is mediated by an effect of splenectomy on numbers of circulating leukocytes or on the antibacterial activity of mouse blood.


The capsular polysaccharide of pneumococcus type IX. The capsular polysaccharide of Type IX pneumococcus contains D-glucose, N-acetyl-D-glucosamine, and D-glucuronic acid. Complete hydrolysis is difficult. All of the N-acetylglucosamine is resistant to oxidation by periodate, but the other two sugars are degraded in part. Chemical and quantitative serological data are consistent with the linkage of two D-glucose residues 1 --> 4, as in maltose; others may be linked 1 --> 3. Part, at least, of the glucuronic acid and N-acetylglucosamine is linked to glucose.


Gas physiology in space operations.

Gas physiology in space operations.


Compounds affecting the central nervous system. 3. Substituted 1,1-diaryl-t-aminopropanols and related compounds.


Studies on crystalline D-amino acid oxidase. 3. Substrate specificity and sigma-rho relationship.


Sequential periodate oxidation of the slpha-acid glycoprotein of human plasma.


The enzymatic synthesis of dihydrofolate and dihydropteroate in cell-free preparations from wild-type and sulfonamide-resistant pneumococcus.


Characteristics of Clostridium pasteurianum ferredoxin in oxidation-reduction reactions.


Social desirability in individual performance on thirteen MMPI scales.


Head nurse, maternal or executive?

Head nurse, maternal or executive?


Effect of hemicholinium no. 3 on the response of frog rectus abdominus muscle to acetylcholine.


Programmed interpretation of MMPI and CPI.


Selection of larvae of a laboratory colony of Culex pipiens fatigans Wiedemann for DDT-resistance.


Complicated rheumatoid disease.

Complicated rheumatoid disease.


The discovery of pneumococcal type transformation: an appreciation.


Errors in clinical trials.

Errors in clinical trials.


Organization of a clinical trial.

Organization of a clinical trial.


Partial recording of dental caries in incidence studies.


Analysis of caries increments by age and tooth surface in fluoridated and nonfluoridated populations, by electronic computer.


Clinical criteria for the diagnosis of the incipient carious lesion.


Toledo 10 year study shows fluoridation as major factor in reduction of DMF teeth.


The paraproteinemias. II.

The paraproteinemias. II.


Evidence for a Poisson distribution of miniature end-plate potentials and some implications.


Electron microscope observations on the structure and discharge of the stenotele of hydra. Sections of the stenotele type of nematocyst of Chlorohydra hadleyi have revealed that the stenotele, upon firing, completely everts its stylets and spines and the long, thin tubule, much as the eversion of the tubule of the nematocyst of the jewel anemone (Picken, 1953; Robson, 1953). Alternative mechanisms for supplying the energy necessary to forcefully discharge the stenotele contents are discussed as well as the possible significance of several regions containing highly ordered periodic structure. The origin of nematocysts as kinetosomal derivatives is discussed as a possibility suggested by the symmetry of the stenotele contents and the structure, location, and function of the cnidocil.


Factors affecting arterial blood flow and its measurement.


Influence of reserpine and guanethidine on vascular reactivity and antihistamine constrictor action in the microcirculation.


Optical rotatory properties of D-aminoacid oxidase.


The distribution and properties of transhydrogenases in insect tissues.


Cholinoceptive receptors of crayfish stretch receptor neurones.


5-Dehydroshikimate reductase in the tea plant (Camellia sinensis L.). Properties and distribution. 1. A method for the extraction of 5-dehydroshikimate reductase (EC 1.1.1.25) from tea plant tissues in an active soluble state has been developed. It is dependent on the use, in the extraction medium, of an insoluble polyphenol adsorbent (Polyclar AT), which prevents the polyphenols present from precipitating all the proteins. 2. The enzyme has the following properties: pH optima at pH10.1 in glycine-sodium hydroxide buffer and at pH7.7 in tris-hydrochloric acid buffer; K(m) (NADP) 32mum and K(m) (shikimate) 0.43mm; and NADP-specificity. It was completely inhibited by 0.33mm-p-chloromercuribenzoate and this inhibition was completely reversed by 10mm-cysteine. Iodoacetate and arsenite inhibited the enzyme to a smaller extent. 3. The specific activity of the enzyme was higher in the parts of the actively growing shoot tips (third leaf>stem>second leaf>first leaf>bud) than in the mature leaves. However, the mature leaves had the greatest total activity. 4. The importance of these findings with respect to flavanol biosynthesis in tea plants is discussed.


Some structural features of the antigenic groupings involved in the cross reaction of oat glucan with type 8 horse antipneumococcal serum.


Structure-activity relationships in the cyproheptadine series.


Enzyme-coenzyme complexes of pyridine nucleotide-linked dehydrogenases. Enzyme-reduced coenzyme binary complexes produce previously unreported shifts in the spectrum of the free coenzyme. These shifts give rise to difference spectra which resemble a general environmental change for reduced diphosphopyridine nucleotide (DPNH) in the glutamic dehydrogenase-DPNH complex, and indicate a more specific enzyme-coenzyme interaction for yeast alcohol dehydrogenase-DPNH, isocitrate dehydrogenase-TPNH, and lactic dehydrogenase-DPNH complexes.


On the dissociation of haemoglobin molecules in strong salt solutions.


A technique for improved visualization of the umbilical vessels.


Cerebrospinal fluid pressure during flurothyl convulsive and electroconvulsive therapies.


Prevention and treatment of severe insect sting reactions.


Current trends in child psychiatry.

Current trends in child psychiatry.


Fragmentation of community health services.


Pulmonary tuberculomas simulating metastatic hypernephroma: report of case.


Cancer of the rectum and pregnancy.

Cancer of the rectum and pregnancy.


Mental health in Appalachia.

Mental health in Appalachia.


Suicide in Chicago: a call for action.

Suicide in Chicago: a call for action.


The child safety and drug safety acts.

The child safety and drug safety acts.


The image of the doctor.

The image of the doctor.


Beta-phenylisopropylhydrazine (JB-516) on septal hyperirritability and brain amine levels in the rat.


Viral encephalitis study on fifty cases at Jamalpur. (A preliminary report).


Cross infection produced by tetracycline-resistant pneumococci.


On the nature of the pneumococcal activator substance.


Photosynthetic phosphorylation and electron transport.


Malic dehydrogenase isozymes.

Malic dehydrogenase isozymes.


The activation of the delta-5-3-keto steroid isomerase in rat adrenal small particles by diphosphopyridine nucleotides.


The effect of dichloroisoproterenol, a beta-adrenergic blocker, on ureteral function.


The testes and body-image formation in transvestitism.


The population of germ cells in immature male rats following irradiation at birth.


The Leeuwenhoek lecture, 1965. Some controversial aspects of bacterial sexuality.


The ultrastructure of male germ cells in rats x-irradiated at birth.


The second Royal Society Nuffield lecture. Anthropological models and social reality.


'Bacillus piliformis' (Tyzzer) and Tyzzer's disease of the laboratory mouse. I. Propagation of the organism in embryonated eggs.


'Bacillus piliformis' (Tyzzer) and Tyzzer's disease of the laboratory mouse. II. Mouse pathogenicity of B. piliformis growth in embryonated eggs.


Interrelationships of myeloid and lymphoid cells: studies with chromosome-marked cells transfused into lethally irradiated mice.


Cross-reactions of streptococcal group N teichoic acid in antipneumococcal horse sera of types VI, XIV, XVI, and XXVII.


Separation by gas chromatography of alcohol-ethylene oxide adducts.


Gastric secretion of rats after test meals.


The effect of atropine, histamine liberators and antihistamines on the absorption of DF32P by mice, rats and guinea pigs.


An analysis of the irritant action of dimethyl sulphoxide.


The concentration and biosynthesis of nicotinamide nucleotides in the livers of rats treated with carcinogens. 1. The oxidoreduction state and concentration of both NAD and NADP as well as the maximum potential activities of NMN adenylyltransferase and NAD(+) kinase have been measured in the livers of rats treated for 14-28 days with 4-dimethylamino-3'-methylazobenzene, 4-dimethylamino-4'-fluoroazobenzene, alpha-naphthyl isothiocyanate or ethionine and in primary hepatomas induced by 4-dimethylamino-3'-methylazobenzene. 2. The total NAD and total NADP both decreased in the livers of rats treated with either azo-dyes or alpha-naphthyl isothiocyanate but not in those treated with ethionine. The activities of NMN adenylyltransferase and NAD(+) kinase did not alter appreciably after such treatments. 3. In the primary hepatomas the concentrations of both NAD and NADP fell drastically and the activities of NMN adenylyltransferase and NAD(+) kinase fell to about 50% of the control activities. 4. No correlation could be established between the concentrations of the nucleotides and the activities of the enzymes synthesizing them. It appears, however, that a relationship exists between the NAD content of the tissue and the amount of NADP present. 5. The results are discussed with respect to the control of NAD and NADP synthesis by ATP. At the concentrations of NAD normally present in the cell it is suggested that NAD may be a rate-limiting substrate in NADP synthesis.


The effect of nivalin on respiration in steroid narcosis. (Experimental study).


On the life-history of rhizostome medusae. IV. Cephea cephea.


Two undescribed species of Uranotaenia from the Philippines (Diptera: Culicidae).


The fine structure of differentiating interstitial cells in Hydra.


Orthostatic paroxysmal ventricular tachycardia.


Invertebrate adhering surfaces: secretions of the starfish, Asterias forbesi, and the coelenterate, Hydra pirardi.


Physiologic and pharmacologic basis of treatment in respiratory allergy.


The effect of mephentermine on digitalis-induced arrhythmias.


Comparison of B.W. 62-235 and lidocaine with respect to cardiovascular, anti-arrhythmic and local anesthetic actions.


Studies on the auricular stimulating action of nicotine.


Similarity of schizophrenia and the psilocybin syndrome as determined by objective methods.


The release of a metabolically active lipid fraction from the arterial wall in vitro.


Member personality and group counseling interaction.


Corrected (for curtailment) correlations between the Marlowe-Crowne social desirability scale and the MMPI.


Relationship of the MMPI K scale and a measure of self-disclosure in a normal population.


Anthranilic acid hydroxylation by rabbit-liver microsomes.


The mechanism of the respiratory stimulation during phagocytosis in polymorphouclear leucocytes.


Evaluation of insecticidal, fumigant and repellent properties of lemongrass oil.


Factors affecting the chain length of fatty acids synthesised by lactating-rabbit mammary glands.


Bud determination in hydra.

Bud determination in hydra.


The biosynthesis of squalene and sterols in fish.


Present status of indoklon convulsive treatments.


Observations on the histamine forming capacity of mouse tissues and of its potentiation after adrenaline. 1. The histamine forming capacity (h.f.c.) was determined in minced or homogenized skin, lung, skeletal muscle or stomach of mice weighing 18-20 g using radioactive (14)C histidine as substrate and determining the radioactive (14)C histamine formed by conversion to its dibenzenesulphonyl derivative.2. The optimal pH for the formation of histamine was 7.0-7.5 for lung and skin, 6.5-7.5 for skeletal muscle. For stomach a more acid pH was optimal and depended on substrate concentration.3. The formation of histamine increased with an increase of the substrate histidine.4. The formation of histamine was not affected by the presence in the incubation mixture of chlorpromazine, pyridoxal-5-phosphate, non-radioactive histamine or benzene. The addition of aminoguanidine slightly increased the formation in skin, lung and skeletal muscle but not in stomach. The formation was unchanged when incubation was in an atmosphere of nitrogen instead of air.5. H.f.c. for stomach of normally fed mice varied 170-fold. For stomachs of mice unfed for 16 hr, h.f.c. was much lower and it varied only sevenfold.6. Injection of adrenaline into mice increased h.f.c. of the skin, lung and skeletal muscle. With skin tissue a linear log. dose log. response relation was demonstrated. The injection of adrenaline caused however either no or only a slight increase in the h.f.c. of stomach tissue.7. The effect of adrenaline on h.f.c. in skin, lung and skeletal muscle was not abolished by alpha- or beta-adrenergic blocking agents either injected separately or together before the injection of adrenaline.


Steroid hydroxylations. 3. The role of reduced nicotinamide--adenine dinucleotide phosphate (NADPH).


Comparative effects of acetylcholine, butyl-nor-synephrine (Vasculat), noradrenaline, and ethyl-adrainol (Effonti) on resistance, capacitance, and precapillary sphincter vessels and capillary filtration in cat skeletal muscle.


Distribution of D-amino acid oxidase in bovine and human nervous tissues.


Surveillance for arthropod-borne encephalitis in Maryland.


Enzyme histochemical study of the motor nerve cells in axonal reaction.


Asymmetry of calculated messenger RNA.

Asymmetry of calculated messenger RNA.


The dissociation of reticulocyte ribosomes.


Gas physiology in space operations.

Gas physiology in space operations.


Neurological, EEG, and psychophysiological findings before and after Sealab II. Rep No. 66-19.


Studies of 3,4-benzpyrene, 3-methylcholanthrene, chlordane, and methyltestosterone as stimulators of hepatic microsomal enzyme systems in the rat.


Nucleotides of microorganisms. XI. The occurrence of guanine propionate in Claviceps paspali Stevens and Hall.


Tension headache, a psychiatric study.

Tension headache, a psychiatric study.


Report on experiences in Swaziland.

Report on experiences in Swaziland.


Hemo-dynamic effects of glucagon in the splanchnic area.


The automobile and the sick child.

The automobile and the sick child.


Alterations in reactivity to acetylcholine in myasthenia gravis and carcinomatous myopathy.


The pharmacology of the hemicholiniums.

The pharmacology of the hemicholiniums.


Studies of the anticariogenic effect of fluorides in toothpaste.


Report on the 17th National Dental Health Conference.


Stimulation of hepatic microsomal drug-metabolizing  enyme systems in primtes byDDT.


Two functionally different dihydroorotic dehydrogenases in bacteria. Taylor, W. H. (Portland State College, Portland, Ore.), M. L. Taylor, and D. F. Eames. Two functionally different dihydroorotic dehydrogenases in bacteria. J. Bacteriol. 91:2251-2256. 1966.-We have investigated the relationship between the two kinds of dihydroorotic dehydrogenases produced by bacteria. A pseudomonad, capable of growth on a salts medium with glucose, aspartate, glycerol, or orotate as the carbon source, was isolated from lake bank mud. A particle-bound dihydroorotic dehydrogenase, similar to the biosynthetic enzyme in Escherichia coli, was formed by the pseudomonad when the carbon source was orotate, glucose, glycerol, or aspartate. A soluble, degradative nicotinamide adenine dinucleotide phosphate-linked dihydroorotic dehydrogenase, as well as the particle-bound biosynthetic enzyme, was formed when the pseudomonad was cultivated on orotate. The biosynthetic enzyme links to oxygen or ferricyanide, but not to pyridine nucleotides. Zymobacterium oroticum, when cultivated on glucose, contained only the biosynthetic type of dihydroorotic dehydrogenase. The presence of two functionally different dihydroorotic dehydrogenases in the pseudomonad was suggested on the basis of the following observations: (i) the two enzyme activities were separated by centrifugation; (ii) the pyridine nucleotide-linked activity was formed only when orotate was present in the growth medium; and (iii) the biosynthetic enzyme was stable to storage at -20 C for 4 months, whereas the degradative enzyme activity was destroyed by storage under these conditions.


The action of elapidae venoms on smooth muscles.


Ganglionic blocking action of some methylpiperidines.


Excerpts of the American Dental Society of Anesthesiology's Second Pain Control Conference.


Effect of catecholamines on smooth muscle motility and phosphorylase activity.


Blockade of epinephrine- and ouabain-induced cardiac arrhythmias in the dog heart-lung preparation.


II. Practical preventive dentistry.

II. Practical preventive dentistry.


Effects of coniine on peripheral and central synaptic transmission.


The neuropharmacology of 2-(omicron-chlorophenyl)-2-methylaminocyclohexanoe hydrochloride.


Antibody deficiency in paraproteinemia.

Antibody deficiency in paraproteinemia.


Poison control in foreign countries.

Poison control in foreign countries.


Tetrazolium reductase activity of the enzymatic systems of oxidation of reduced nicotinamide nucleotides in mammalian brain.


Generation of reducing power in chemosynthesis. II. Energy-linked reduction of pyridine nucleotides in the chemoautotroph, Nitrosomonas europaea.


Substrate interaction with hydroxylase system in liver microsomes.


Antagonism of anticonvulsants by adrenergic blocking agents.


Mosquito bites.

Mosquito bites.


Report of the International Conference on the perinatal and infant mortality problem of the United States.


Westernization, insecurity, and Sinhalese social structure.


Studies of the metabolic effects of acute insulin deficiency. II. Changes in hepatic glycolytic and krebs-cycle intermediates and pyridine nucleotides.


Effect of hydramitrazine (Lisidonil) in the treatment of neurogenic bladder dysfunction.


A simple spot screening test for galactosemia.


The effect of primaquine and acetylphenylhydrazine on the enzymatic and nonenzymatic oxidation of reduced pyridine nucleotides.


The lay person's fear of a doctor.

The lay person's fear of a doctor.


Group discussion.

Group discussion.


The training of medical secretaries.

The training of medical secretaries.


Medical history and the general practitioner.


The diagnosis and treatment of cancer in a general practice.


Patients receiving barbiturates in an urban general practice.


A practice pattern of patient-doctor contact.


The clinical trial in general practice.

The clinical trial in general practice.


Cardiac complications of Bornholm disease.


Some aspects of current rheumatological practice.


A cervical smear campaign in a general practice.


Social class factors relevant for psychiatric treatment.


Deiodinase activity in the rat thyroid when the organic binding was blocked by excess iodine.


An epic of the coal fields.

An epic of the coal fields.


Individual viewpoints of social desirability.


Evaluation of a program distributing ipecac syrup.


A clinical trial of brompheniramine maleate in chronic urticaria.


Bamethansulphate as a vasodilator in clinical practice.


CNS stimulant drugs and conditioning treatment of nocturnal enuresis: along term follow-up study.


Clinical evaluation of syrup of ipecac as an emetic. Report of studies on twenty-three children.


On the conversion of cholesterol to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one. Bile acids and steroids 168.


A toxic cardiac reaction to drugs absorbed percutaneously.


A controlled trial of A.N.P. 235 ("Lucidril") in senile dementia.


Exercise-induced asthma.

Exercise-induced asthma.


Life cycle and patterns of development of Plasmodium berghei in normal and experimental hosts.


Mosquito transmission of malaria.

Mosquito transmission of malaria.


A long-acting antihistamine.

A long-acting antihistamine.


The earloe algesimeter. 2. The effect on pain threshold of certain phenothiazine derivatives alone or combined with meperidine.


A hydroxy fatty acid dehydrogenase in Euglena gracilis.


Thin-layer chromatography of phosphate esters of biologic interest.


A report on the Southern Conference of Dental Deans and Examiners.


Variations in the frequency of the human duodenal basic electrical rhythm in health and disease.


A report on the seventeenth National Dental Health Conference.


The medical and human performance problems of living under the sea. Recent undersea experiments in the United States and France showed that divers can live and work effectively for many days from dwellings placed on the continental shelf to depths down to 432 feet. If prolonged exposure to the hostile underwater environment is to be tolerated successfully, existing physical, biological and equipment hazards must be recognized, prepared for and, when possible, circumvented.


Neurochemical bases of tremor and other disorders of movement. Monkeys inflicted with specific unilateral electrolytic lesions in the upper brain stem developed extrapyramidal disorders. Hypokinesia of the limbs was associated contralaterally with a lesion of the substantia nigra and depletion of striatal dopamine. Choreiform movements were observed in animals that had, contralaterally, a lesion severing the most dorsomedial fibres of the cerebral peduncle and the rubro-tegmentospinal tract, associated with depletion of striatal serotonin. Monkeys showing sustained postural tremor and hypokinesia had lesions affecting these three tracts contralaterally and loss of striatal dopamine and serotonin on the lesion side. Of many drugs tested, only harmaline and harmine affected the dyskinesias. The nigrostriatal fibres appear to be dopaminergic; the cerebral peduncular (dorsomedial) fibres, serotoninergic. The role of striatal dopamine and serotonin in the control of normal movements and posture of the limbs represents the first directly demonstrated function of these amines in the central nervous system.


Responses of extremely obese patients to starvation.


The spermatogram of patients with cryptorchidism. A follow-up study.


Mitochondrial biochemical changes and glucose-KCl-insulin solution in cardiac infarct.


Effect of changes in gastric secretion on protein tolerance after portacaval shunt.


Objective measures of depression.

Objective measures of depression.


Dihydrofolate reductase from the L1210R murine lymphoma. Fluorometric measurements of the interaction of the enzyme with coenzymes, substrates, and inhibitors.


Studies on the Egyptian Nigella sativa L. IV. Some pharmacological properties of the seeds' active principle in comparison to its dihydro compound and its polymer.


Male infertility. Cryptorchidism in the stallion.


Some physico-chemical properties of poliovirus variants differing in chromatographic behaviour on diethylaminoethyl cellulose columns.


Enzymic synthesis of dimethyl selenide from sodium selenite in mouse liver extracts.


Adenosine triphosphatase associated with Newcastle disease virus. Conditions for its optimum activity.


Peculiarities and site of synthesis of viral and cellular ribonucleic acids in measles virus-infected cells.


Interaction of Japanese encephalitis virus with mouse liver cells and with the receptor extracted therefrom.


Pathogenicity of tick-borne encephalitis virus. VII. Relation between infective and pathogenic activity for rhesus monkeys.


The role of interferon in tick-borne encephalitis virus-infected cells. V. Further knowledge about the role of interferon in the induction and maintenance of persistent infection.


Changes caused by, and multiplication of virus Coxsackie in tissues of susceptible animals.


Pathogenicity of Tribec virus for Macaca rhesus monkeys and white mice.


Materials on measles pathogenesis and vaccinal process.


On two types of interaction of Rous sarcoma virus (Carr strain) with mammalian cells in vivo.


"Adaptation" of a strain of neurovaccinia and of dermovaccinia to organ cultures of chick embryo skin.


Interaction of heart glycosides and viruses.


Study of the antigenic structure of Coxiella burneti. V. Detection of phase I of Coxiella burneti by indirect fluorescent antibody technique.


Electron microscope studies on the specificity of virus-like particles contained in the colostrum in bovine leukosis.


The role of the lymphatic system after direct administration of tick-borne encephalitis virus into the blood stream of susceptible white mice.


Optimal conditions for interferon formation in chick embryo cell cultures infected with tick-borne encephalitis virus.


Elution from DEAE-cellulose of certain echo 19 virus strains.


Cutaneous reaction to dexbrompheniramine maleate.


Attraction of anhidrotic subjects to mosquitoes.


Evidence for the metabolism of glycerol by skeletal muscle and the presence of a muscle nicotinamide-adenine dinucleotide phosphate-dependent glycerol dehydrogenase.


The conversion of 7-dehydrocholesterol into cholesterol.


Studies of flavin-adenine dinucleotide-requiring enzymes and phenothiazines. II. Structural requirements for D-amino acid oxidase inhibition.


Species differences in methemoglobin reductase activity.


On the structure and catalytic function of mammary glucose 6-phosphate dehydrogenase.


Electron carriers of the bovine adrenal cortical respiratory chain and hydroxylating pathways.


The stereochemistry of the nicotinamide adenine dinucleotide-specific isocitric dehydrogenase reaction.


Crystallization and properties of p-hydroxybenzoate hydroxylase from Pseudomonas putida.


Association-dissociation phenomena of D-amino acid oxidase.


Studies on the mechanism of fatty acid synthesis. 13. The role of beta-hydroxy acids in the synthesis of palmitate and cis vaccenate by the Escherichia coli enzyme system.


Elimination of false negative results with the FPN Forest test for phenothiazine derivatives in urine.


Derivatives of 2-azabicyclo[2.2.2]octane. I.


Aldosterone stimulation in vitro. 3. Site of action of different aldosterone-stimulating substances on steroid biosynthesis.


Fractionation of the photochemical systems of photosynthesis. I. Chlorophyll contents and photochemical activities of particles isolated from spinach chloroplasts.


Electron transfer components in the photosynthetic system of the diatom Navicula pelliculosa.


A sensitive radioassay for sulfhydryl groups with tetraethylthiuram disulfide.


Adrenergic mechanisms in the isolated cat tracheal muscle and effect of some polypeptides.


Effects of phenyl acetate and its analogues on isolated guinea-pig small intestine.


The influences of andrenotropic drugs and noradrenaline on the histamine release in cardiac anaphylaxis in vitro. 1. The regional distribution (auricles, ventricles and septum) of histamine and its release during anaphylaxis were studied in isolated perfused guinea-pig hearts.2. The highest value of histamine content was found in the right auricle, the lowest in the left ventricle and septum, both in normal hearts, and in the hearts subjected to anaphylaxis.3. The fraction of the total histamine released in the course of 24 min by antigen was 50%. The fraction released from the different regions of the heart was similar. No evidence was found for release of 5-hydroxytryptamine.4. A relation was found between the distribution of mast cells and the tissue concentration of histamine. The highest number of mast cells per unit area was found in the right auricle; the lowest in the left ventricle.5. The histamine release by antigen was reduced by previous treatment with (+)-tubocurarine; the histamine release by (+)-tubocurarine was depressed by previous challenge of the heart with antigen.6. Reserpine reduces histamine release. Perfusion of reserpine-treated hearts with noradrenaline partially restored histamine release.7. beta-Adrenergic blocking agents (dichloroisoproterenol and pronethalol) reduced histamine release.8. The drugs tested did not modify the tissue concentration of histamine.9. The possibility of a modulating activity of catecholamines on histamine release in cardiac anaphylaxis is discussed.


Pyridine nucleotide transhydrogenase from Chromatium.


Studies on the metabolism of adipose tissue. XIX. An evaluation of the major pathways of glucose catabolism as influenced by acetate in the presence of insulin.


Dental caries and nutrition in Lebanon.

Dental caries and nutrition in Lebanon.


Purification and properties of mutant and wild-type dihydrofolate reductase from Diplococcus pneumoniae.


Studies on the induction and repression of enzymes in rat liver. IV. Effects of cortisone and phenobarbital.


Aldosterone synthesis by adrenal mitochondria.


On the mechanism of chemical and enzymatic reduction of folate and dihydrofolate.


Mechanism of neuro-muscular blockade by some antihistaminic compounds.


The effect of galantamine on the blood pressure of the rat.


The effects of hexamethonium and morphine on transmission in the superior cervical ganglion of the rabbit.


Insecticide susceptibility and resistance in populations of Anopheles gambiae, Culex fatigans and Aedes aegypti in southern Nigeria.


Pulmonary atelectasis in subjects breathing oxygen at sea level or at simulated altitude.


Pulmonary changes with convulsions induced by drugs and oxygen at high pressure.


A mutant strain of Chlamydomonas reinhardi lacking ribulose diphosphate carboxylase activity.


Identification of suicidal behavior by means of the MMPI.


Repression and psychopathology: a ross-validation failure.


Vascular permeability changes in inflammation. I. The role of endogenous permeability factors in ultraviolet injury.


Occurrence and prevention of postasphyxial intraventricular pressure gradiants.


Purification and properties of a chloroplast-protein containing photoreducible disulfide bond.


An evolutionary approach to human behaviour.


Neurotic disorders in urban practice: a three-year follow-up.


Peptic ulcers in an Essex village.

Peptic ulcers in an Essex village.


The number of items of general medical service provided by a general practitioner in one year (1964).


Group practice--future patterns?

Group practice--future patterns?


Thiazides and diabetes mellitus.

Thiazides and diabetes mellitus.


Skin infections in infancy and childhood. A 12 months study in general practice.


Mental illness in general practice.

Mental illness in general practice.


Serum liver function tests in general practice. An essay in "do-it-yourself" biochemistry.


A new preparation for the topical treatment of acne vulgaris. Report of a year's study.


General or family practice--a science?

General or family practice--a science?


The structure of the College of General Practitioners; a radical view.


Wax in the ears and its management.

Wax in the ears and its management.


The accuracy of haemoglobin determinations with the Spencer haemoglobinometer.


The viability of spores of some Bacillus species.


The effect of yeast cells in the heating medium on the heat resistance of Bacillus stearothermophilus spores.


A limit test for p-chloroacetanilide and other impurities in paracetamol and phenacetin using thin-layer chromatography.


Adjuvant-induced arthritis: effects of certain drugs on incidence, clinical severity, and biochemical changes.


Isolation of guanosine diphosphate uronic acids from a marine brown alga, Fucus gardneri Silva.


Beta-adrenergic blockade in angina pectoris: a method of treadmill assessment.


A new method of preparation of D-amino acid oxidase apoprotein and a conformational change after its combination with flavin adenine dinucleotide.


Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. 3. Aminoadipic semialdehyde-glutamate reductase.


Human placental 17-beta-estradiol dehydrogenase. 3. The separation of A 17-beta-estradiol-dependent transhydrogenase.


Pronethalol-induced reversal of adrenergic vasodepression.


Studies on azeotropic mixture of fluoromar and Freon 113.


Multiplication of virulent and avirulent strains of Newcastle disease virus and interferon production in susceptible animals.


Effects of pronase on influenza virus.

Effects of pronase on influenza virus.


Conditions of isolation of infectious ribonucleic acid from influenza virus.


Pathogenicity of tick-borne encephalitis virus for the chicken embryo. IV. Age as a factor of non-specific resistance of chicken embryos to the lethal activity of the virus.


Reproduction of Tahyna virus in chick embryo cell cultures studied by biological and morphological methods.


The role of bone marrow in the multiplication of tick-borne encephalitis virus in the early viraemic phase in experimentally infected mice.


Effect of pH, bivalent cations Mg++ and Ca++, trypsin and papain on Tahyna virus.


Demonstration of B virus (herpesvirus simiae) by the direct fluorescent antibody technique.


Soluble antigen of Rickettsia prowazeki.


Paraffin embedding techniques for immunofluorescent demonstration of neurotropic viruses.


Localization of rhinopneumonitis equorum virus antigens in calf kidney cell culture.


Isolation of a presumably new virus from unengorged Ixodes ricinus ticks.


Non-complementing rct40- mutant of poliovirus.


Persistent infection of monkey kidney stable cells with Coxiella burneti.


Isolation of two plaque variants from the prototype strain of B virus (Herpesvirus simiae).


Adenovirus hemagglutination of African Green monkey erythrocytes.


Insusceptibility of cell cultures to the action of exogenous interferon as the result of virus infection of the cells.


Serological relationships among members of the cowpea mosaic virus group.


Propagation of street rabies virus in primary cultures of dog kidney cells.


Stabilization of ECHO virus haemagglutinins. II. Stabilization with organic compounds.


Pharmacological study of the central nicotine-sensitive cholino-receptors.


Stabilization of ECHO virus haemagglutnins. I. Thermal inactivation of haemagglutinins and their cationic stabilization.


Diverticulum in the posterior urethra in a case of agenesis of the left kidney and retention of the left testicle.


Epileptogenic effect on extradural and extracranial cobalt.


Design and development of a water vapor electrolysis unit. NASA CR-607.


Thermal integration of electric power and life support systems for manned space stations. NASA CR-543.


Antagonism of adrenergic blockade by pronethalol.


Oxybutynin--a musculotropic antispasmodic drug with moderate anticholinergic action.


The pharmacology of actomol and related compounds.


Spectrum analysis of electroencephalographic changes induced by some psychoactive agents. Their possible relationship to changes in cerebral biogenic amine levels.


Effects of luteinzing hormone and nicotinamide adenine dinucleotide phosphate on synthesis of progestational steroids by rabbit ovarian tissue in vitro.


11-beta-Hydroxysteroid metabolism by mouse brain and glioma 261.


The relationship between caries activity, flow rate, total nitrogen and the mucin content of saliva.


The effects of confinement as a factor in manned space flight. NASA CR-511.


Cytochemical studies of embryonic development to metamorphosis in the gymnoblastic hydroid. Pennaria tiarella.


Feasibility of removing gaseous contaminants from manned space-cabin atmospheres by ionic processes. AMRL-TR-66-22.


Undersea air supply.

Undersea air supply. The interior air of a simulated underwater habitation was continuously washed or scrubbed with sea water by means of a gas exchanger of the venturi type. The sole method for supplying oxygen and removing carbon dioxide was the scrubbing process. A microburner placed inside the experimental habitation chamber continued to burn until it was intentionally extinguished. Two rats maintained in the chamber for 8 hours suffered no discernible ill effects.


Magnesium pemoline and behavior.

Magnesium pemoline and behavior.


Influence of ambient temperature in the process of replacement of nonshivering by shivering thermogenesis during postnatal development.


Cholinergic mechanisms in the sinus node with particular reference to the actions of hemicholinium.


The screening of hereditary metabolic defects among newborn infants. THE PRESENT COMMUNCIATION DESCRIBES THE USE OF FOUR APPROACHES TO THE DETECTION OF HEREDITARY METABOLIC DISORDERS: (1) the bacterial inhibition assay, (2) the reduction of nicotinamide adenine dinucleotide phosphate (NADP), (3) the use of paper chromatography, and (4) other specific methods. Using small quantities of capillary blood or urine, practical and simple methods have been devised for the diagnosis of 30 inborn errors of metabolism through screening programs.


Drip infusion cholangiography.

Drip infusion cholangiography.


Immunodiffusion studies on the reaction of influenza virus with specific antibody and nonspecific serum beta-inhibitor.


Some properties of Newcastle disease virus ribonucleic acid.


The effect of bamethan on cardiovascular response.


On the participation of nuclei in the synthesis of poliovirus ribonucleic acid.


Mode of action of interferon on the early stage of vaccinia virus multiplication in chick embryo fibroblasts.


Propagation of influenza virus in diploid cell strains and BHK-21 cells.