Lung cancer death rates still rising; uterus cancer down.


Fabray's disease.

Fabray's disease.


Drinking involved in home accidents, company finds.


Actinomycin-sensitive induction of tyrosine transaminase and tryptophan pyrrolase by amino acids and tryptophan.


Growth hormone inhibition of hydrocortisone induction of tyrosine transaminase and tryptophan pyrrolase and its reversal by amino acids.


Inhibition of adrenal steroid metabolism by heparin in vivo.


Studies on the mechanism of fatty acid synthesis. 18. Preparation and general properties of the enoyl acyl carrier protein reductases from Escherichia coli.


The cariostatic effect of calcium sucrose phosphate in a group of children aged 5-17 years.


The effects of histamine and other naturally occurring imidazoles on neurones on Helix aspersa.


Studies on the pressor responses produced by bradykinin and kallidin.


Acid-soluble metabolites of adenine-2-14C-adenine-8-14C in 2,6-diaminopurine-sensitive and 2,6-diaminopurine-resistant L strain mouse cells.


The influence of bretylium on the interactions of infused sympathomi- metic amines and tyramine in the reserpine-treated pithed rat.


Cardioaccelerator release in Periplaneta americana (L). Focal electrical stimulation of the brain of Periplaneta americana evokes the release of a factor with high cardioaccelerator activity. Results of extirpation of components of the retrocerebral complex from an isolated head preparation imply that the corpus cardiacum is the critical component of this system. The cardioaccelerator is a heat-stable proteinaceous compound.


Arbovirus studies in Bush Bush Forest, Trinidad, W. I., September 1959-December 1964. II. Field program and techniques.


Arbovirus studies in Bush Bush Forest, Trinidad, W. I., September 1959-December 1964. 3. Entomologic studies.


Arbovirus studies in bBush Bush forest, Trinidad, W. I., September 1959-December 1964. V. Virus isolations.


Arobovirus studies in Bush Bush Forest, Trinidad, W. I., September 1959-December 1964. VI. Rodent-associated viruses (VEE and agents of groups C and Guamá): isolations and further studies.


Effects of lipolytic and antilipolytic substances on adenosine 3',5'-monophosphate levels in isolated fat cells.


Effects of casein hydrolysate on the induction and regulation of tyrosine-alpha-ketoglutarate transaminase in rat liver.


Purification and properties of a nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogeanse from Gluconobacter cerinus.


The conversion of testosterone to 5-alpha-androstan-17-beta-ol-3-one by rat prostate in vivo and in vitro.


The value of intact tissue sections for studying metazbolic inter-actions between the cytoplasm and mitochondria.


Oxidation of D-amino acids by a particulate enzyme from Pseudomonas aeruginosa. A particulate d-amino acid dehydrogenase has been partially purified from cell free extracts of Pseudomonas aeruginosa grown on dl-valine as the source of carbon and energy. A standard assay was developed which utilized 2,6-dichlorophenol-indophenol as the electron acceptor. The pH optimum for enzyme activity ranged from 6.0 to 8.0, depending on the amino acid assayed. The enzyme was most active with monoamino-monocarboxylic amino acids and histidine. The Michaelis constant for d-phenylalanine was found to be 1.3 x 10(-3)m d-phenylalanine. Constants could not be calculated for the other amino acids oxidized because anomalous plots of V as a function of V/S were obtained. Spectra of enzyme preparations reduced with d-valine or sodium hydrosulfite exhibited adsorption bands typical of the alpha, beta, and gamma bands of cytochromes as well as bleaching in the flavin region of the spectrum. When dl-valine was added to a medium with glycerol as the energy source, d-amino acid dehydrogenase was detected after the addition of valine and was produced at a rate directly proportional to the synthesis of total protein. The enzyme was formed when d-valine, l-valine, or dl-alanine was the source of carbon and energy, but not when glucose, glycerol, or succinate was the energy source.


The inhibiting effect of amitriptyline, bamipin and chlorprothixene on the content of adrenaline and noradrenaline in the adrenal vein of dogs and their adrenomedullary secretion caused by acetylcholine.


Indolelactate dehydrogenase from Clostridium sporogenes.


Histochemical study of 3-beta-, 3-alpha-, 11-beta-, and 17-beta-hydroxysteroid dehydrogenases in the adrenocortical tissue and the corpuscles of Stannius of Fundulus heteroclitus.


Starvation metabolism and plasma corticosterone with reference to the actions of metopirone and propylthiouracil.


Androgen production in vitro by phalarope gonadal tissue homogenates.


Immunochemical studies on cross-reactions of antipneumococcal sera-V. Cross-reactions of horse antipneumococcal type II serum with E. coli M-II polysaccharide, dextran and hemocyanin-ortho-azophenyl-beta-glucuronide.


Specific purification of equine anti-SII antibodies by precipitation with a hemocyanin-glucuronide conjugate.


Fluorometric measurement of pyridine nucleotide reduction in the giant axon of the squid. By monitoring the fluorescence of the isolated giant axon of the squid Loligo pealei, it was possible to follow changes in its oxidation-reduction state as caused by the action of anoxia, cyanide, Amytal, and azide. The response to oxygen depletion was very rapid, the NAD within the axon being 90% reduced within 1-2 min. Cyanide and Amytal gave essentially similar results, although somewhat longer periods of time elapsed during their onset and washout periods. The extent of NAD reduction was essentially the same under conditions of anoxia and treatment with cyanide and Amytal. Azide was less effective in this respect, and at comparatively high levels of concentration (25-50 mM) gave values of 40% or less of the reduction observed with the other inhibitors. The application of ouabain and strophanthidin gave no observable NAD reduction. Variations in the time required to consume given quantities of dissolved oxygen before and after stimulation indicated an increase of 10-20% in oxygen uptake rate associated with activity, although this figure appeared to be a function of the surface-to-volume ratio of the axon. A biochemical analysis of axoplasm for oxidized and reduced pyridine nucleotide was made. Fluorometric examination of centrifuged axoplasm indicated that the NAD-NADH was largely confined to the mitochondria of the axon.


Effects of acetylcholine and biogenic amines on pulmonary smooth muscle in the African lungfish, Protopterus aethiopicus.


The blood flow in the forearm in patients with cardiac failure. I. The relationship between the cardiac output and the blood flow in the forearm.


A combined field ionisation-electron impact ion source for high molecular weight samples of low volatility.


Ribonucleic acid from reovirus as seen in protein monolayers by electron microscopy.


Interferon-like substance produced in chick fibroblast cells inoculated with human adenoviruses.


Mode of action of O-seryl-N-acetylgalactosaminide glycohydrolase.


Some properties of the cathepsin from the mucosa of rat colon.


The "bad trip"--the etiology of the adverse LSD reaction.


The psychological assessment of police candidates.


Psychiatric aspects of Wilson's disease (hepatolenticular degeneration): results of psychometric tests during long-term therapy.


Therapeutic results of prophylactic treatment for "classic" migraine with antaminic substance (B P 400 Sandoz).


Gardner's syndrome without polyposis?

Gardner's syndrome without polyposis?


The possible role of an adrenergic mechanism in the antianginal action of papaverine and prenylamine.


Action of central nervous system stimulant and depressant drugs in the intact animal. 3. Dual action of 5-ethyl-5-(1,3-dimethylbutyl)barbiturate, dilantin and beta-methyl-beta-eta-propylglutarimide.


Effect of heparin on the metabolism of cortisone by subcellular fractions of rat liver.


Differentiation of middle piece in Hydra at its tentacular site.


Diffusion pathway of ascorbic acid in Hydra.


Immunochemical studies on myxoviruses. I. Heterogeneity of V-antigens obtained y disruption influenza viruses.


Effect of catecholamines and adrenergic blockade on sodium transport of isolated frog skin.


Effects of dehydroepiandrosterone and diet protein on liver enzymes and lipogenesis.


Lincomycin and penicillin G in the treatment of mild and moderately severe pneumococcal pneumonia. A comparative study.


Tubularia regeneration: radial organization of tentacles, gonophores, and endoderm.


Studies of nicotinic acid metabolism in Astasia longa. I. Incorporation of nicotinic acid into pyridine derivatives in exponentially growing and in synchronized cultures.


Studies of nicotinic acid metabolism in Astasia longa. II. Pathway and regulation of nicotinamide adenine dinucleotide biosynthesis in cell-free preparations.


The mechanism of 6-deoxyhexose synthesis. II. Conversion of deoxythymidine diphosphate 4-keto-6-deoxy-D-glucose to deoxythymidine diphosphate L-rhamnose.


5-Keto-D-fructose. V. Phosphorylation by yeast hexokinase.


Identification of D. pneumoniae.

Identification of D. pneumoniae.


Effects of propranolol and its optical isomers on the radiocalcium uptake and the adenosine triphosphatases of skeletal and cardiac sarcoplasmic reticulum fractions (SRF).


Pharmacology of Go-1002.

Pharmacology of Go-1002.


Steric aspects of adrenergic drugs. 8. Optical isomers of beta adrenergic receptor antagonists.


Effects of chronic administration of the amphetamines and other stimulants on behavior.


Supply of antivenenes.

Supply of antivenenes.


Tetrodotoxin: effects on fish and frog melanophores. Tetrodotoxin blocks the response of killifish melanophores to electrical stimulation of their melanin-aggregating nerves. The direct response of killifish or frog melanophores to hormones is not affected. Since there is no effect on melanin aggregation resulting from the release of adrenergic neurotransmitter in killifish melanophores, we conclude that tetrodotoxin acts by blocking nerve conduction.


Coelenterate biology: experimental research.


Pseudomonas infections of the foot following puncture wounds.


Effects of ethionine on thyroid function.


Ovulation suppressors, psychological functioning, and marital adjustment.


Congestive heart failure in a 61-year-old man.


Military psychiatry, occupation, and refugee problems in Israel.


Sugar retention, cofactor levels, and leakage of metabolites in x-irradiated, starved yeast cells.


The actions of general anesthetic agents on tracheal smooth muscle.


Neurohumoral interaction in the rat amygdala after central chemical stimulation. The interactions of chemically induced thirst and hunger with deprivation-induced hunger and thirst, respectively, were studied in the amygdala. The results suggest direct neurohumoral blocking at this locus, rather than mediation through activated circuits.


Effects of physical training on physiologic and behavioral characteristics of cardiac patients.


Tyrosine-alpha-ketoglutarate transaminase: induction by epinephrine and adenosine-3',5'-cyclic phosphate. Epinephrine and the N6-O2'-dibutyryl analog of adenosine-3', 5'-cyclic phosphate both are effective inducers of tyrosine-alpha-ketoglutarate transaminase in explants of fetal rat liver maintained in organ culture. Combinations of these inducers with each other and with hydrocortisone, another inducer, yielded results which suggest that cyclic adenylic acid is an intermediate in the induction by epinephrine and that the mechanism by which it induces is different from that by which hydrocortisone operates.


Psilocybin-induced changes in psychologic function, electroencephalogram, and light-evoked potentials in human subjects.


Personality structure as the main determinant of drug induced (model) psychoses.


Cold Spring Harbor Symposia.

Cold Spring Harbor Symposia.


Neuromuscular effects of beta-adrenergic blockers and their interaction with skeletal muscle relaxants.


Failure of the Hering-Breuer reflex to account for tachypnea in anesthetized man: a survey of halothane, fluroxene, methoxyflurane, and cyclopropane.


NAD- and NADP-dependent malate dehydrogenase in wheat.


Susceptibility of mosquito larvae to a synthetic juvenile hormone, farnesyl diethylamine.


Reaction of L-2-acetylamino-2-carbomethoxyethanesulfonyl chloride with ammonia.


Inhibition of rat spleen proteinases by serum.


The role of general metabolites in the biosynthesis of natural products. I. The terpene marrubiin.


The role of general metabolites in the biosynthesis o natural products. II. The paraffin heptacosane.


Properties of uridine and thymidine phosphorylating enzymes of Zea mays.


Effects of substrate on heat inactivation of Taka-amylase A.


Influence of pH on the autolysis of intracellular proteins in homogenates of rat spleen and liver.


On the kinetics of inhibition of rat-brain acetylcholine esterase by Sevin.


The role o eneral metabolites in the biosynthesis of natural products. 3. The phytosterol 22, 23-dihydrostigmasterol.


Particular activity of naphthacene derivatives as inducers of zoxazolamine hydroxylase synthesis in rats.


Further evidence for the existence of cyclic and non-cyclic photophosphorylation in vivo by means of desaspidin ad DCMU.


Some observations on the food vacuole of Paramecium auralia.


The neutral and the acid proteinase from calf bone marow.


Common insect, mite and parasite problems in the United States.


The sorbitol pathway. Enzyme localization and content in normal and diabetic nerve and cord.


The mechanism of end product inhibition of serine biosynthesis. I. Purification and kinetics of phosphoglycerate dehydrogenase.


Reduced triphosphopyridine nucleotide oxidase-catalyzed alterations of membrane phospholipids. I. Nature of the lipid alterations.


Reduced triphosphopyridine nucleotide oxidase-catalyzed alterations of membrane phospholipids. II. Enzymic properties and stoichiometry.


Stimulant drugs and temporary increases in avoidance responding.


Mechanism of the pressor effect of amodiaquin and chloroquine in methylamphetamine-pretreated anesthetized dogs.


Renal arteriography in the assessment of renal infarction.


Heterogeneity of reduced pyridine nucleotide-tetrazolium reductase system in rat liver. A quantitative histochemical study.


How I treat nummular eczema.

How I treat nummular eczema.


Synthetic analogues of oxytocin: an approach to problems of hormone action.


Molecular aspects of neurohypophysial hormone release.


Crystallization of complexes of neurophysins with vasopressin and oxytocin.


Isolation from the posterior lobe of the pituitary gland of a protein specifically but loosely binding oxytocin and vasopressin.


Calcitonin: a review of its discovery and an account of purification and action.


Inhibition by calcitonin of bone resorption induced in vitro by vitamin A.


Neurophysin and neurohypophysial hormones.


Common cytochemical and ultrastructural characteristics of cells producing polypeptide hormones (the APUD series) and their relevance to thyroid and ultimobranchial C cells and calcitonin.


Recent advances in the physiology of gastrin.


Chemical studies of some mammalian gastrins.


Cryptorchism and testicular tumorigenesis.


Specific features of adaptation of a human organism to prolonged stay in sealed chambers.


The role of malic enzyme in bovine adrenal cortex mitochondria.


Non-glycolytic sugar metabolism in human erythrocytes. I. Xylitol metabolism.


Specificity of naphthoquinones as cofactor for NADPH oxidation by liver microsomes.


NADPH inhibition and in vitro effect of gonadotrophins on the cholesterol sidechain-cleaving enzyme system in bovine corpora lutea.


Effects of ACTH and whole-body x-irradiation on the concentrations of enzymes, nicotinamide nucleotides and cytochromes in the rat adrenal.


Relationships among attitudes in pregnancy and other maternal characteristics.


Extramitochondrial NADPH and cholesterol side chain-cleaving enzyme system in the heavy mitochondria of bovine corpora lutea.


The infrared spectra of substituted 2-(diphenylmethoxy)-N,N-dimethylethylamine hydrochlorides.


Errina cruenta, a new stylasterine coral from New Zealand.


Calyptopora reticulata n. g., n. sp., a stylasterine coral from deep water in the New Zealand region.


Paradoxical effects of phenothiazines.

Paradoxical effects of phenothiazines.


The surgical treatment of the cryptorchid testis.


Ethylbutyl-malonic acid-di(m-amino)-anilide, a new, non-steroid antiinflammatory compound.


The incidence of urinary tract anomalies in cryptorchid boys.


Today's drugs.

Today's drugs.


Trial of a new antihistamine--tavegyl.

Trial of a new antihistamine--tavegyl.


The health team of 1968.

The health team of 1968.


Gallstone ileus.

Gallstone ileus.


Improved method of bronchography in uncooperative patients respiratory diseases in institutions for the mentally retarded.


Clinical trial of a unique hydrocortisone containing topical aerosol in a variety of dermatologic disorders.


Diagnosis of pneumatosis intestinalis.

Diagnosis of pneumatosis intestinalis.


Medical progress in the prevention of childhood lead intoxication.


Neurologic complications of oral contraceptives.


Inherent faults in government medicine.

Inherent faults in government medicine.


To better understand your jewish patient.


Daniel Drake in Illinois.

Daniel Drake in Illinois.


Prediction of juvenile probation violators.


MMPI study of negro mental hygiene clinic patients.


Effects of acetylcholine on the heart.

Effects of acetylcholine on the heart.


Induction of tryptophan oxygenase and tyrosine aminotransferase in mice.


Biosynthesis of isoleucine and valine in Mycobacterium tuberculosis H37 Rv.


Dominance-submissiveness and competition in a mixed-motive game.


The effect of various agents in the levels of homocarnosine in rat brain.


The scores of Eysenck's criterion groups on some MMPI scales related to emotionality and extraversion.


The effect of catecholamines on unit activity in afferent nerves from the adrenal glands. 1. Afferent discharges were observed in dissected filaments of nerves to the adrenal gland in the rabbit and cat.2. Systemic intravenous and close intra-arterial injections of (-)-adrenaline and (-)-noradrenaline caused cessation or depression of the spontaneous firing rate.3. Intravenous injection of acetylcholine and electrical stimulation of the splanchnic nerve also depressed the afferent discharge rate.4. Modification of blood pressure levels by chemical and mechanical means did not modify the afferent discharge.5. Alpha blocking agents (ergotamine and phenoxybenzamine) blocked the effect of (-)-adrenaline on the firing rate. Beta blocking agents (dichloroisoprenaline and propranolol) were without effect.6. It is suggested that an afferent system is present in the adrenal gland. Within this system are chemosensitive receptors which may constitute the afferent limb of a local feed-back loop involved in adrenal catecholamine release.


Effects of catecholamines on rat mesentery mast cells.


The need for early reduction of blood pressure: illustrated by the long-term results of treatment of hypertension.


Ganglionic transmission in the autonomic nervous system.


The bacteriology of the lower respiratory tract. Bronchoscopic study of 100 clinical cases.


Chemotherapeutic studies of mycobacterial infections in mice. Of six antibiotics investigated, streptovaricin C had the most marked chemotherapeutic effect on Mycobacterium kansasii infections in mice. By the intraperitoneal route this antibiotic caused elimination of the pathogens from all organs. Kanamycin eliminated the pathogens from the lungs of all animals and from the spleens and livers of most of them. Bluensomycin also removed the pathogens from the lungs of all animals, and spectinomycin and lincomycin, from the lungs of the majority of the animals. The three latter antibiotics lowered the bacterial counts in liver and spleen. Streptovaricin C also decreased the bacterial counts in brain, spleen, and liver of mice inoculated intracerebrally with M. kansasii. In one experiment it completely eliminated this pathogen from the spleen and almost completely from the liver. The effect of streptovaricin C on the cerebral infection was more marked than that of streptovaricin complex. Respiratory and cerebral infections of mice with M. avium, serotypes I and II, were limited by streptovaricin C, and marked decreases of the bacterial counts in brain, lungs, spleen, and liver were observed.


A sensitive and specific isotopic assay for the estimation of tyrosine transaminase.


Inhibition of DNA-dependent RNA polymerase reaction of Escherichia coli by an antimicrobial antibiotic, streptovaricin.


Gonadal hypoplasia in Gir cattle.

Gonadal hypoplasia in Gir cattle.


Nitrite formation from hydroxylamine and oximes by Pseudomonas aeruginosa. Nitrite was formed from hydroxylamine and several oximes by intact cells and extracts of Pseudomonas aeruginosa. The activity was induced by the presence of oximes in the culture medium. Nitroalkanes were not intermediates in the conversion of acetaldoxime, acetone oxime, or butanone oxime to nitrite, since nitromethane inhibited the formation of nitrite from the nitro compounds but not from the corresponding oximes. The oxime apparently functions as a constant source of hydroxylamine during growth of the bacterium. Hydroxylamine at low concentration was converted stoichiometrically to nitrite by extracts of the bacterium; high concentrations were inhibitory. Nicotinamide adenine dinucleotide phosphate, oxygen, and other unidentified cofactors were necessary for the reaction. Actively nitrifying extracts possessed no hydroxylamine-cytochrome c reductase activity. Hyponitrite, nitrous oxide, and nitric oxide were not metabolized.


Metabolism of carbohydrates by Pasteurella pseudotuberculosis. Cell-free extracts of Pasteurella pseudotuberculosis and P. pestis catalyzed a rapid and reversible exchange of electrons between pyridine nucleotides. Although the extent of this exchange approximated that promoted by the soluble nicotinamide adenine dinucleotide (phosphate) transhydrogenase of Pseudomonas fluorescens, the reaction in the pasteurellae was associated with a particulate fraction and was not influenced by adenosine-2'-monophosphate. The ability of P. pseudotuberculosis to utilize this system for the maintenance of a large pool of nicotinamide adenine dinucleotide phosphate could not be correlated with significant participation of the Entner-Doudoroff path or catabolic use of the hexose-monophosphate path during metabolism of glucose. As judged by the distribution of radioactivity in metabolic pyruvate, glucose and gluconate were fermented via the Embden-Meyerhof and Entner-Doudoroff paths, respectively. With the exception of hexosediphosphatase, all enzymes of the three paths were detected, although little or no gluconokinase or phosphogluconate dehydrase was present unless the organisms were cultivated with gluconate. The significance of these findings is discussed with respect to the regulation of carbohydrate metabolism in the pasteurellae, related enteric bacteria, and P. fluorescens.


MMPI profiles as a function of chronological age.


Methylenetetrahydrofolate dehydrogenase of the amethopterin-resistant strain Streptococcus faecium var. durans A and its repressibility by serine. The methylenetetrahydrofolate dehydrogenase of the amethopterin-resistant strain Streptococcus faecium var. durans A(k) was purified 100-fold. Because it is extremely labile, this enzyme required protection by 1 mm nicotinamide adenine dinucleotide phosphate (NADP(+)) during purification; 0.01 mm EADP(+) with 0.1% bovine plasma albumin stabilized the purified enzyme during storage at -20 C. Although the enzyme has properties of sulfhydryl enzymes, thiol compounds were not stabilizers. Oxidation of methylenetetrahydrofolate, catalyzed by the purified enzyme preparation, is NADP(+)-specific and yields methenyltetrahydrofolate and the reduced pyridine nucleotide. K(m) values for NADP(+) and for 5,10-methylenetetrahydrofolate (prepared as the formaldehyde adduct of biologically synthesized l,l-tetrahydrofolate) were calculated to be 0.021 and 0.026 mm, respectively. Neither purine bases and their derivatives nor serine inhibited the reaction. In growing cultures, the differential rate of synthesis of the methylenetetrahydrofolate dehydrogenase was dependent upon the composition of the medium. A medium which contained acid-hydrolyzed casein, and thus an exogenous source of serine, was repressive for this enzyme. In a serine-free, completely defined medium, the amount of folate added (for serine synthesis de novo) affected the duration of the initial exponential growth phase. At the termination of this phase, which primarily reflected the onset of a decreased rate of serine biosynthesis, synthesis of the methylenetetrahydrofolate dehydrogenase was derepressed. Exogenous serine in the completely defined medium prevented the derepression. Furthermore, physiological concentrations of l-serine were repressive not only for the dehydrogenase but also for the methenyltetrahydrofolate cyclohydrolase and the serine hydroxymethyl-transferase. Concomitantly, the differential rate of synthesis of the formyltetrahydrofolate synthetase of S. faecium var. durans A(k) was increased. Apparently, serine regulates the differential rates of syntheses of these enzymes.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 25-1968.


Self-confrontation in psychotherapy reviewed. Videotape playback as a clinical and research tool.


Emerging concepts for briefer psychotherapy: a review.


Studies of drug effects on electrically induced extensor seizures and clinical implications.


Differences in sensitivity of arterial smooth muscles to inhibition of their contractile response to depolarization by potassium.


Some properties of a nitrite reductase from Pseudomonas denitrificans.


Studies on yeast sulfite reductase. I. Purification and characterization.


Studies on yeast sulfite reductase. II. Partial purification and properties of genetically incomplete sulfite reductases.


Optical and photochemical properties of chlorophyll a solubilized in aqueous solutions of surfactants.


Chloroplast reactions of photosynthetic mutants of Scenedesmus obliquus.


Photoreduction of amino-acid oxidases in the presence of free flavin and the effect of urea.


Mechanism of enzyme action. IV. Isolation by crystallization of the fully reduced form of D-amino acid oxidase.


A comparative study of the reversibility of the reaction catalysed by bacterial lipoamide dehydrogenase.


Effect of adrenergic stimulation on ion transport across skin of living frogs.


A new method for detecting the fake good response set on the MMPI.


Phenylthiourea taste blindness and MMPI personality patterns in adult Caucasion females.


The meaning of the Taulbee-Sisson configurational score on the MMPI with neurosurgical patients.


Normative findings for the frequency of MMPI critical items.


Glutamate dehydrogenase of Drosophila larvae.


Effects of antilipolytic agents on dibutyryl cyclic AMP induced lipolysis in adipose tissue.


Observations on man in an oxygen-helium environment at 380 mm. Hg. total pressure. V. Chromosome profiles.


Influence of bradykinin on isolated canine venous strips.


The significance of decided and query answers to lie-items in a personality questionnaire.


4th FEBS Meeting's Plenary Lecture. The biosynthesis of deoxyribonucleotides.


On the reaction of borohydride with D- and L-amino acid oxidases.


The stability of sucrose monolaurate: rate of formation of lauric acid.


Role of hemoprotein P-450 in fatty acid omega-hydroxylation in a soluble enzyme system from liver microsomes.


Concentric cylinder creep investigation of pharmaceutical semi-solids.


Use of the analogue computer to examine the quantitative relation between urinary pH and kidney reabsorption of drugs partially ionized at physiological pH.


Modification of the pyridoxine-induction of tyrosine transaminase in rat liver by thyroid hormones and by alloxan diabetes.


Organizational behaviors and adaptations to organizational change of sensitizer and represser problem-solving groups.


Age and seasonal differences in the effects of some neurotropic substances.


Evolution of neuro-humoral regulation of the excitation in interneuronal synapses during ontogeny.


Effect of CO2 on phtophosphorylation in vivo as revealed by the light-dependent Cl minus uptake in Elodea densa.


Can cells be synchronized by exposure to periodically varying ultrastrong magnetic fields?


Acid proteinase from the small intestinal mucosa of rats.


Cholesterol in Physalia physalis.

Cholesterol in Physalia physalis.


Utilization of injected maltose and sucrose by insects: evidence for non-intestinal oligosaccharidases.


Prospects for a manned space laboratory.


Reactivity of thiol groups in active and inactive forms of a mitochondrial nucleoside diphosphokinase.


D-amino acid oxidase. II. Studies of substrate-competitive inhibitors.


Occult fracture-subluxation of the midtarsal joint.


Application of the analogue computer to pharmacokinetic and biopharmaceutical studies with amphetamine-type compounds.


Interaction of anti-inflammatory drugs with serum proteins, especially with some biologically active proteins.


An investigation of the effects of angiotensin on the release of neurohumoral transmitters at motor, adrenergic and cholinergic nerve terminals.


The effect of temperature on end-plate depolarization of the rat diaphragm produced by suxamethonium and acetylcholine.


The effects of tremorine and oxotremorine in hyperthyroid mice.


Role of pH in the coacervation of the systems: gelatin-water-ethanol and gelatin-water-sodium sulphate.


Peripheral and central components in the hyperthermic effect of desipramine in reserpinized rats.


The action of endotoxin in mobilizing free fatty acid.


Decrease of cerebral 5-hydroxytryptamine by 3,4-dihydroxyphenylalanine after inhibition of extracerebral decarboxylase.


The effect of imipramine on central monoamine neurons.


A device for the rapid measurement of rat foot volume.


The effects of prostaglandin E1 on isolated bronchial muscle from man.


The effects of (+)-amphetamine and (+)-phenmetrazine on the noradrenaline and dopamine levels in the hypothalamus and corpus striatum of the rat.


The distribution of small concentrations of active ingredients in tablet granules.


The penetration temperature of aqueous sodium dodecyl sulphate solutions into solid long-chain alcohols.


Greater lowering of brain and adrenal catecholamines in group-housed than in individually-housed mice administered DL-alpha-methyltyrosine.


Disulfiram and the drug-induced effects on motility.


Dental research: the past two decades. National Institute of Dental Research interdisciplinary programs have broadened the base of dental science.


The briefest psychiatric encounter. Acute effects of evaluation.


Fluoride dentifrices. A review of clinical trials in the United Kingdom.


Caries-inhibition after seven years of unsupervised use of an amine fluoride dentifrice.


The effect of neurohormones on blastic, mitotic and plasmocytic reactions of the draining lymphatic gland in rats with post-adiuvans polyarthritis.


Periarteritis nodosa complicated with bilateral spontaneous massive perirenal hemorrhage.


Tartaric acid metabolism. VII. Crystalline hydroxypyruvate reductase (D-glycerate dehydrogenase).


Tartaric acid metabolism. VI. Crystalline oxaloglycolate reductive decarboxylase.


Aldehyde dehydrogenase. I. Purification and properties of the enzyme from Pseudomonas aeruginosa.


The developmental formation of liver glucose 6-phosphatase and reduced nicotinamide adenine dinucleotide phosphate dehydrogenase in fetal rats treated with thyroxine.


A detailed study of contaminants produced by man in a space cabin simulator at 760 mm. Hg. SAM-TR-67-16.


Cryogenically trapped trace contaminants analyzed by ionizing gas chromatography. SAM-TR-67-68.


Indirect calorimetry in low pressure environments. SAM-TR-67-27.


Acclimatization versus tolerance to stress; an annotated bibliography. SAM-TR-67-95- VOL I.


Isolation of Turlock virus and a member of the Bunyamwera group, probably Cache Valley virus, from Alberta mosquitoes.


Hypersecretion of insulin, glucagon and gastrin in a kindred with multiple adenomatosis.


Malate dehydrogenase: evidence for tetrameric structure in Mus musculus. Two electrophoretically distinct variants of supernatant nicotinamideadenine dinucleotide phosphate-dependent malate dehydrogenase exist in mice (Mus musculus). They are controlled by codominant alleles segregating at an autosomal locus. The two forms exist in a polymorphic condition in wild populations of Mus musculus and are fixed in a homozygous condition in inbred lines. These genetic electrophoretic variants are used here to study the subunit structure of this enzyme. Evidence indicating a tetrameric structure for mouse nicotinamideadenine dinucleotide phosphate-dependent malate dehydrogenase is presented. This interpretation is based on the occurrence in heterozygote tissue extracts of five electrophoretically distinct enzymes. This is the predicted phenotype for tetramers composed of two types of subunits which associate randomly in heterozygotes forming three hybrid enzymes having mobilities intermediate between the parental forms.


Hepatic microsomes and drug oxidation.

Hepatic microsomes and drug oxidation.


An epidemic of tularemia in Sweden during the summer of 1967.


Neurological syndromes of the tarsal tunnels.


Enzyme induction in perfused rat liver by glucagon and other agents.


Epidemiologic research--1964-1967.

Epidemiologic research--1964-1967.


Determination of glutathione reductase activity in microgram samples of tissue, quantitative histologic distribution of the enzyme in the rat adrenal and effect of adrenocorticotropin.


In vitro action of mescaline. Possible mode of action.


Biologically active pyrazoles.

Biologically active pyrazoles.


Alpha-phenyl-alpha(2,3-cyclohexenyl) acetic acid derivatives as potential antispasmodics.


Urinary excretion of pheniramine and its N-demthylated metabolites in man--comparison with chlorpheniramine and brompheniramine data.


Spectrophotometric determination of acetaminophen, phenylephrine hydrochloride, codeine phosphate, and pyrilamine maleate in tablets or powder.


Genetics of audiogenic seizures: II. Effects of pharmacological manipulation of brain serotonin, norepinephrine and gamma-aminobutyric acid.


Effects of DNA repair in transformation-heterozygotes of pneumococcus.


Elevation and depression of hepatic tyrosine transaminase activity by depletion and repletion of norepinephrine.


Behavioral facilitation: the interaction of imipramine and desipra- mine with amphetamine, alpha-pipradrol, methylphenidate, and thozalinone.


A gelatin film method for improved histochemical localization of dehydrogenases in plant cells.


Liberation of alpha-methyldopamine as a "false" sympathetic transmitter after pretreatment of cats with alpha-methyldopa and disulfiram.


Achalasia or cardiospasm in Great Dane puppies.


Chemotaxis of polymorphonuclear leukocytes.


Conversion of lysine to saccharopine by human tissues.


Total care of the chronic bronchitis patient. An evaluation of twenty years' experience.


Anti-fibrillary and anti-adrenaline activity of beta-receptor blocking drugs.


Increased susceptibility of mice to seizures after some anticonvulsant drugs.


Studies of intestinal microflora. V. Fecal microbial ecology in ulcerative colitis and regional enteritis: relationship to severity of disease and chemotherapy.


Effects of thyroidectomy and triiodothyronine administration on oxidative enzymes in rat liver microsomes.


Cranial bruits in purulent meningitis in childhood.


The etiology of acute respiratory infections. 3. The role of viruses and bacteria.


End results in treatment of malignant testicular tumors.


Red blood cell and plasma distribution during experimental vasodilator hypotension.


Experimental mosquito-transmission of Plasmodium knowlesi to man and monkey.


In vitro activity of minocycline, a new tetracycline.


Dengue-virus recovery by direct and delayed plaques in LLC-MK2 cells.


Development of a diurnal resting box to collect Culiseta melanura (COQ.).


Drugs and disease as mosquito repellents in man.


Suicide among physicians.

Suicide among physicians.


Gastrointestinal bleeding, hypertension and paraproteinemia.


Psychological aspects of space flight.

Psychological aspects of space flight.


Measurement of personality and attitude: applications to clinical research.


Investigation of some possibilities of producing type 3 vaccine poliovirus with greater genetic stability. I. Preliminary experiments with passage variants.


Antibody response of guinea pigs and white mice to nucleoprotein component of influenza virus as studied by gel double diffusion.


Studies on the pathogenesis of Aujeszky's disease. I. Distribution of the virulent virus in piglets after peroral infection.


Antibody response to natural influenza A2 infection of man as studied by gel double diffusion.


The significance of the skin and the regional lymph nodes in the penetration and multiplication of tickborne encephalitis virus after subcutaneous infection of mice.


Visualization by immunofluorescence of elementary bodies and their aggregates in materials from skin lesions in poxvirus infections.


Process of adaptation of street rabies virus to dog kidney cell primary cultures.


The growth of arboviruses in mosquito cells in vitro.


Reproduction of tick-borne encephalitis virus and inhibition of formation and action of interferon in the presence of deuterium oxide.


Production of interferon-like inhibitor in chickens after secondary induction by bacteria and virus.


In vivo induction of an interferon-like inhibitor by kanamycin.


Vaccinia in white rats after total gamma irradiation.


Influence of DEAE-dextran on plaque production by Semliki forest virus.


Virological studies on tick-borne encephalitis in natural foci in Austria.


Electrophoretic separation and electron microscopy of influenza A2 virus components.


The use of polyvinyl superchloride in morphological studies of tissue cultures.


Double neutralization of fowl plague virus reproduced in chick myeloblasts.


Pseudorabies virus with lost virulence for rabbits after intra-muscular inoculation, obtained from persistently infected cell cultures.


Chromatographic characteristics of crude preparations of Rous sarcoma virus strains on hydroxylapatite.


Enhanced infectivity of combined bottom and middle components of red clover mottle virus.


Isolation of a cytopathic agent from the tick Haemaphysalis punctata.


Adrenal cortex.

Adrenal cortex.


The role of bacterial and viral infection in chronic bronchitis.


Subjective change with medical student therapists. II. Some determinants of change in psychoneurotic outpatients.


Dental disease in cerebral palsied children.


The Fifth National Conference of the Indian Academy of Pediatrics held at Ahmedabad from 4th to 7th January 1968. Address.


Oxidative enzymes in postcastrational adrenal tumors of mice.


Synthesis of 5-alpha-pregnane-3,20-dione by fetal and adult human adrenals.


17-beta-hydroxysteroid dehydrogenase from human red blood cells.


ACTH release in response to metyrapone in diabetes insipidus patients.


Orf of the external auditory meatus.

Orf of the external auditory meatus.


Time-course of changes in rat liver enzyme activities after initiation of a high protein regimen.


An experimenter variable: the psychologist-clergyman.


Alleviation of the leg abnormality in zinc-deficient chicks by histamine and by various anti-arthritic agents.


Affective differential: comparison of emotion profiles gained from clinical judgment and patient self-report.


Coping, defense and socially desirable responses.


Steroidogenic enzyme systems in the rat adrenal glands during postnatal development.


Fracture of the os calcis--the problem in general.


Adrenal cortical activity in depression.


Localization and regulation of two NAD nucleosidases in Ehrlich ascites cells.


Eyewitness.

Eyewitness.


Comparative evaluation of antinuclear factor tests in rheumatic disorders.


The early natural history of juvenile rheumatoid arthritis. A 10-year follow-up study of 100 cases.


Anaesthetists-in-law.

Anaesthetists-in-law.


Dimethyl sulfoxide: breakdown of blood-brain barrier?


A study of psychodynamic changes in untreated neurotic patients. I. Improvements that are questionable on dynamic criteria.


Enlargement of the guinea pig salivary gland caused by catecholamines or tooth amputation.


Anxiety as a function of taking the MMPI.


Interrelationships between personality inventories: the 16 PF, the MMPI, and the MPI.


Perception of and reaction to ambiguity by repressors and sensitizers: a construct-validity study.


Thematic expression of sexual conflict under varying stimulus conditions.


Effect of background items on responses to personality inventory items.


Dipole moments and pharmacological activity of cyclic ureas, cyclic thioureas, and the N, N'-dimethylated compounds.


Influence of some psychotropic and adrenergic blocking agents upon amphetamine stereotyped behaviour in white rats.


Pulmonary edema induced by adrenaline and related amines in rats, and its modification by various pretreatments.


Glycemic effects of solanine in rats.

Glycemic effects of solanine in rats.


Tests of learning and memory with Cylert.


Formation of Dg-1-amino-2-propanol by a highly purified enzyme from Escherichia coli.


Aquatic insects associated with midwestern waste stabilization lagoons.


Histamine-infusion test. 1. Control subjects.


Physiological evaluation of SEALAB II. Deep Submergence Systems Project Office, Department of the Navy.


Reported neurologic disorders following live measles vaccine.


Personality study of nocturnal teeth-grinders.


A brief ranking method as an alternative to Thurstone scaling procedures.


The anatomy and ultrastructure of the labyrinth of the lamprey (Lampetra fluviatilis L.).


Ly-A and Ly-B: two systems of lymphocyte isoantigens in the mouse.


The rate of equilibration in a competitive n drug system and the auto-inhibitory equations of enzyme kinetics: some properties of simple models for passive sensitization.


The identification of dopamine in the rabbit's carotid body.


Synaptic organization of the frog retina: an electron microscopic analysis comparing the retinas of frogs and primates.


Phasic myocardial blood flow in hemorrhagic hypotension. Effect of beta sympathetic blockade.


Microbial genetics in relation to medicine.


Purification and properties of lipoamide dehydrogenase from yeast, Candida krusei.


A five year study of bacteriology and prophylactic chemotherapy in patients with chronic bronchitis.


Histological and ultrastructural study of the muscular and nervous systems in Hydra. I. The muscular system and the mesoglea.


Histological and ultrastructural study of the muscular and nervous systems in Hydra. II. Nervous system.


Use of the analogue computer to predict the distribution and excretion of drugs under conditions of fluctuating urinary pH.


Dental care.

Dental care.


Comparison of various methods for the determination of serum creatine phosphokinase.


Management of the child with bronchial asthma. Pathologic, physiologic and pharmacologic problems.


Structure--function relationships in gastrin-like peptides.


Dentition of Bedouins in Israel. I. Epidemiology.


Simple ulcer of the terminal ileum.

Simple ulcer of the terminal ileum.


Rectal vascular resistance in ulcerative colitis.


Role of the bovine adrenal cortical pyridine nucleotide transhydrogenase in steroid 11 beta-hydroxylation.


In vitro enzymic omega oxidation of medium-chain fatty acids in mammalian tissue.


Chemistry of coelenterates. VI. Occurrence of gorgosterol, a C30 sterol, in coelenterates and their zooxanthellae.


Acute renal failure in pregnancy.

Acute renal failure in pregnancy.


The relationship between caries of the deciduous and permanent teeth in the same child.


The temporo-mandibular syndrome.

The temporo-mandibular syndrome.


Endometriosis of the bladder.

Endometriosis of the bladder.


Apparent ureteropelvic junction obstruction caused by vesicoureteral reflux.


The view box.

The view box.


Historical sketch of psychiatry in Illinois--1940 to 1968.


Dosages for aqueous allergy injections.

Dosages for aqueous allergy injections.


Female genital malignancy.

Female genital malignancy.


The incidence of lipodystrophy in juvenile diabetics.


Smooth muscle and cardiovascular pharmacology of alpha-elaterin-2-D-glucopyranoside glycoside of Citrullus colocynthis.


New derivatives of quinuclidine as potential antihypertensive agents.


Absolute configurations of the enantiomeric pheniramines, methylphenidates, and pipradrols.


Determination of phenylephrine hydrochloride in combination with other drugs.


Changes in activities of some enzymes during in vivo aging of mouse erythrocytes.


Aminoglutethimide inhibition of adrenal desmolase activity.


Iron carbonyl complexes of beta-carotene and lycopene.


Heat and photochemical inactivations of Taka-amylase A and mechanisms of protection by substrate.


Chelation of boric acid with some nucleosides.


On the mode of incorporation of shikimic acid into 2-hydroxy-1,4-naphthoquinone (lawsone).


Inhibition of ribonuclease I in Escherichia coli by polymyxin B.


Acetone treatment for preservation of adult and larval mosquitoes.


Characterization of an imidazolepyruvicacid reducing system from Escherichia coli B +.


Increased sensitivity in fluorometric determinations of nicotinamide nucleotide coenzymes.


Lipid synthesis in Lipomyces lipofer.

Lipid synthesis in Lipomyces lipofer.


CPC. Pleural effusion, cardiomegaly, hepatomegaly, fever, and peripheral neuropathy in a 65-year-old man.


Enzyme histochemistry of osteogenic sarcoma, chondrosarcoma, and giant-cell lesions in jawbones.


Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.


Regulation of electron transport in photosynthesis.


Indoklon convulsive therapy.

Indoklon convulsive therapy.


Allosteric control of the activity of malic enzyme in Escherichia coli.


Regulation of tyrosine-alpha-ketoglutarate transaminase in rat liver. VII. Hormonal effects of synthesis in the isolated, perfused liver.


Effects of polyribonucleotides of known composition on deoxycytidylate and deoxyguanylate kinase activity in Pneumococci.


Enzymic studies of bile acid metabolism. I. 6-beta-Hydroxylation of chenodeoxycholic and taurochenodeoxycholic acids by microsomal preparations of rat liver.


Reduction of palmitoyl dihydroxyacetone phosphate by mitochondria.


Morphogenesis and development of microbodies of hepatocytes of rats during pre- and postnatal growth. In hepatocytes of fetal rats, cytoplasmic organelles identifiable as microbodies appeared, although only a few of them showed nucleoids and most of them generally had an electronlucent appearance due to the low density of their matrices. Some of these microbodies, especially those lacking the nucleoid, showed a substantial connection with granular endoplasmic reticulum (ER), suggesting that microbodies might be formed from granular ER. Agranular tubular profiles projecting from the surface of microbodies were found with a high frequency in fetal and neonatal rats; however, this phenomenon may not provide crucial evidence suggestive of the derivation of microbodies from agranular ER. Growth and maturation of microbodies are considered to be brought about by an enlargement of these organelles, an increase in their matrices, an appearance and enlargement of the nucleoids, and an increase in the enzyme involved. The specific activity of urate oxidase in the isolated nucleoid fraction was significantly lower in the earlier stages of postnatal growth than later. Increases in the enzyme activity per nucleoid (maturation of the nucleoid), in the number of microbodies containing nucleoids (formation of the nucleoid), and in the size of nucleoids (growth of the nucleoid), may contribute to increases in the enzyme activity of the tissues.


2,6-Dialkylpiperazines. V. Synthesis of 2,6-alkylpiperazine derivatives structurally related to cinnarazine.


Social desirability factors and the Eysenck Personality Inventory.


Quinterenol, a new beta adrenergic stimulant.


Influence of age and diet on the induction of hexobarbital-metabolizing enzymes in the mouse.


Further evidence for an unique neurohumoral agent released from brain by morphine given intracerebrally.


Tissue distribution and excretion of phenformin in normal and diabetic animals.


Inhibition of lipid biosynthesis.

Inhibition of lipid biosynthesis.


The effect of ascorbic acid on the cerebral and adrenal catecholamine content in the male rat.


The effect of catecholamines and beta-anti-adrenergic drugs on isolated short-circuited skin of the frog.


Psychopharmacological effects of thiothixene and related compounds.


Comparison of ECS and flurothyl-induced retrograde amnesia in mice.


RNA uptake into intact mammalian cells: rapid incorporation at low temperatures.


Conservative treatment of acute respiratory failure in patients with chronic obstructive lung disease.


Specific antigens released into sea water by contracting anemones (Coelenterata).


The oxidation of drugs by fishes.

The oxidation of drugs by fishes.


Self-image and objective personality study of a sample of juvenile delinquents.


Deiodination of iodinated amino acids by pig thyroid micrsomes.


Cholesterol 20-alpha-hydroxylase and P-450 in a preparation from hog adrenocortical mitochondria.


Taxonomic complexes of arbovirus vectors.


Levels of resistance in ribosomes from genetically linked, streptomycin-resistant mutants of pneumococcus.


Differentiation of primary from secondary vectors.


Evidence for the steroid-induced accumulation of tyrosine-aminotransferase messenger RNA in the absence of protein synthesis.


Dallas calling.

Dallas calling.


The intracellular distribution of free nucleotides in the tobacco leaf. Formation of adenosine 5'-phosphate from adenosine 5'-triphosphate in the chloroplasts. 1. A method of studying the free nucleotides of leaf tissue is outlined and the need for a metal ion-binding agent for the complete extraction of certain nucleotides by aqueous ethanol is established. 2. The method was used to study the effect of illumination or darkening of tobacco plants on the free nucleotides present in the chloroplast and non-chloroplast tissue components. 3. When plants that had been in the dark for a prolonged period were given 30sec. of bright light there was a rapid phosphorylation of ADP to ATP in both chloroplast and non-chloroplast components of the tissue. 4. Where plants were moved into the dark from conditions suitable for rapid photosynthesis there was a rapid conversion of ATP into AMP and the AMP was formed only in the chloroplast fraction. In continuing darkness the AMP remained restricted mainly to the chloroplast fraction for at least 2min., but eventually its concentration fell to the low value that is typical of tobacco leaves during conditions of constant illumination. If the plants were returned to the light for 30sec. the AMP was rapidly rephosphorylated.


Beta adrenergic blocking agents with review of current literature.


Protective effect of certain antihistaminics against the diffusates from burnt rat skin. I.


Antiserotonin properties of some newer antihistaminics. II.


Quantitative gas chromatographic determination of methapyrilene fumarate, ephedrine hydrochloride, and codeine phosphate in syrup.


Quantitative determination of some single and multiple component drugs by gas-liquid chromatography.


Elevation of serum copper following copper sulfate as an emetic.


Comparison of the antiwealing effect of the antiamines BP 400 and cyproheptadine and an antihistamine HS 592.


Dimethpyrindene and a new antihistamine HS 592 (sandoz) in the treatment of severe chronic urticaria.


Effect of chlordiazepoxide on bronchoconstriction.


Arousal time following intravenous anesthetic agents, methohexital and thiopental: effect of doxapram hydrochloride.


The kinetic properties of human erythrocyte glucose 6-phosphate dehydrogenase.


Experiences in the treatment of vasomotor rhinitis.


Polyarteritis nodosa with pulmonary involvement.


The effect of gonadotrophins on the metabolic activity of the testicular Leydig cells in normal infantile rats and in rats pretreated postnatally by oestrogens.


Human water consumption and excretion data for aerospace systems.


Emotional evaluation of medical patients.


Experiments about sex determination in Hydra attenuata Pall.


Prenyl splinting of injuries: a case report.


Psychopathological effects of hypnosis.

Psychopathological effects of hypnosis.


Isolation, purification, and some properties of reduced nicotinamide adenine dinucleotide phosphate-cytochrome C2 reductase from Rhodopseudomonas spheroides.


Armigeres of the Papuan Subregion (Diptera: Culicidae).


The predation of spiders on forest mosquitoes in field experiments.


Formation of bile acids in man: conversion of cholesterol into 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol in liver homogenates. The mechanisms of the conversion of cholesterol into bile acids in man were studied by examining the metabolism of cholesterol-1,2-(3)H, cholest-5-ene-3beta,7alpha-diol-7beta-(3)H, tritiumlabeled 7alpha-hydroxycholest-4-en-3-one, 7alpha,12alpha-dihydroxycholest-4-en-3-one, and cholest-5-ene-3beta,7alpha,12alpha-triol in fractions of liver homogenates. The 20,000 g supernatant fluid catalyzed the conversion of cholesterol into cholest-5-ene-3beta,7alpha-diol, 7alpha-hydroxycholest-4-en-3-one, 7alpha-12alpha-dihydroxycholest-4-en-3-one, and 5beta-cholestane-3alpha,7alpha,12alpha-triol. In the presence of microsomal fraction fortified with NAD(+), cholest-5-ene-3beta,7alpha-diol was converted into 7alpha-hydroxycholest-4-en-3-one, and when this fraction was fortified with NADPH small amounts of cholest-5-ene-3beta-7alpha,12alpha-triol were formed. 7alpha-Hydroxycholest-4-en-3-one was metabolized into 7alpha-12alpha-dihydroxycholest-4-en-3-one in the presence of microsomal fraction fortified with NADPH and into 5beta-cholestane-3alpha,7alpha-diol in the presence of 100,000 g supernatant fluid. Cholest-5-ene-3beta,7alpha,12alpha-triol was converted into 7alpha,12alpha-dihydroxycholest-4-en-3-one in the presence of microsomal fraction fortified with NAD(+). The 100,000 g supernatant fluid catalyzed the conversion of 7alpha,12alpha-dihydroxycholest-4-en-3-one into 5beta-cholestane-3alpha,7alpha,12alpha-triol. The sequence of reactions in the conversion of cholesterol into 5beta-cholestane-3alpha,7alpha-diol and 5beta-cholestane-3alpha,7alpha,12alpha-triol, the subcellular localization of the enzymes, and the cofactor requirements were found to be the same as those described for rat liver.


The polymorphism of phenobarbitone.

The polymorphism of phenobarbitone.


Infrared identification of barbiturates with particular reference to the occurrence of polymorphism.


Effect of electrolytes on coacervation of the systems gelatin-water-ethanol and gelatin-water-sodium sulphate.


The action of ampicillin on Aerobacter (Klebsiella) aerogenes.


The depletion and recovery of noradrenaline in the brain and some sympathetically innervated mammalian tissues after tetrabenazine.


Relaxation of the guinea-pig tracheal chain preparation by N6,2'-O-dibutyryl 3',5'-cyclic adenosine monophosphate.


Blocking action of tetrahydrocannabinol upon transmission in the trigeminal system of the cat.


Potentiation by cocaine and 3,3-di(p-aminophenyl)-propylamine (TK 174) of the effect of isoprenaline and noradrenaline on isolated strips of cat spleen.


A note on the effects of some cholinergic and anticholinergic drugs on the aggressive behaviour and spontaneous electrical activity of the central nervous system in the ant, Formica rufa.


A note on the blockade of uptake of noradrenaline by 4-chloro-alpha,alpha-dimethylphenethylaminopropan-2-one in rodents.


Rate of accumulation and plateau plasma concentration of drugs after chronic medication.


The effect of staphylococcus alpha-toxin on the release of acetylcholine in the coaxially stimulated isolated ileum preparation of the guinea-pig.


Effects of guanoxan on intestinal smooth muscles.


The effect of the chronic administration of sodium barbitone on the exploratory behaviour of rats.


Iodination of angiotensin II.

Iodination of angiotensin II.


Evaluation and control of variability in hormone-stimulated lipolysis in rat adipose tissue.


Uptake of debrisoquin and guanethidine by human blood platelets.


The anticholinesterase activity of physostigmine.


Absence of inhibitory effects of catecholamines on lower vertebrate arterial strip preparations.


XO-XY-XYY mosaicism in a phenotypically abnormal male infant.


Learning and memory enhancement by pemoline and magnesium hydroxide (PMH).


Ictus and amnesia.

Ictus and amnesia.


Effect of counting solution and antihistaminics on platelet volume.


Nature of fibres in Hydra.

Nature of fibres in Hydra.


Chloroform-water partition and other physical characteristics of 8 different adrenergic beta-receptor blocking drugs.


Oral hygiene campaign in Liverpool.

Oral hygiene campaign in Liverpool.


The relationship of cariostasis, oral hygiene, and past caries experience in children receiving three sprays annually with acidulated phosphate-fluoride: three-year results.


Rorschach responses and aggressive characteristics of MMPI F-16 scorers.


A feasibility study of the use of a stannous fluoride mouthwash in a school preventive dentistry program. SAM-TR-67-52.


Genetically determined electrophoretic variations of human phosphogluconate dehydrogenase.


Preparation and pharmacological activity of pyrazole derivatives with potential antihistaminic properties. I. Alkamine ethers of 1-phenyland 1-benzyl-3-methyl-5-hydroxypyrazole.


Studies of the epidemiology of arthropod-borne virus infections at Mitchel River Mission, Cape York Peninsula, North Queensland. I. Mosquito collections, 1963-1966.


Studies of the epidemiology of arthropod-borne viru infections at Mitchell River Mission, Cape York Peninsula, North Queensland. II. Arbovirus infections of mosquitoes, man and domestic fowls, 1963-1966.


Analysis of an experimental model of DNA unwinding.


Gas exchange of algae. IV. Reliability of Chlorella pyrenoidosa. A single culture of Chlorella pyrenoidosa (700 ml) was grown continuously under uniform environmental conditions for a period of 11 months. During this time, the culture remained uncontaminated and its oxygen production, carbon dioxide consumption, and photosynthetic quotient (PQ = CO(2)/O(2)) were monitored on a 24-hr basis. The gas exchange characteristics of the alga were found to be extremely reliable; the average oxygen production was 1.21 +/- 0.03 ml per min, the carbon dioxide consumption was 1.09 +/- 0.03 ml per min, and the PQ was 0.90 +/- 0.01 when changes in both lamp intensity and instrument accuracy were taken into consideration. Such long-term dependability in the production of oxygen, consumption of carbon dioxide, and maintenance of a uniform PQ warrants the use of C. pyrenoidosa in a regenerative life support system for space travel.


Effect of lytic enzymes upon the responsivity of rat adrenals in vitro. I. Effect of trypsin upon the steroidogenic action of reduced triphosphopyridine nucleotide.


Coincident basophilic chronic myelogenous leukemia and pulmonary tuberculosis associated with extreme elevations of blood histamine levels and maturity onset asthma.


Effect of nicotinamide in vivo on thyroid pyridine nucleotides and radioiodine metabolism.


The coronary personality: a critique.

The coronary personality: a critique.


Cross-validation of Purpose-in-Life test based on Frankl's concepts.


In vitro interconversion of estrone and 17-beta-estradiol in human skin and vaginal mucosa.


Studies of common baldness of the stumptailed macaque. II. Enzyme activities of carbohydrate metabolism in the hair follicles.


The isolation and characterization of subcellular fractions from pigmented and unpigmented cells of Rhodopseudomonas spheroides.


Acute antilipolytic effects of ethyl alcohol and acetate in man.


The relation between the pigment content of isolated chromatophores and that of the whole cell in Rhodopseudomonas spheroides.


The nature of the internal fine structure of Rhodopseudomonas spheroides as determined by the study of cell fragments.


Distribution and metabolism of ornithine in Rhodopseudomonas spheroides.


Sclerotherapy of varicose veins.

Sclerotherapy of varicose veins.


The separation and identification of the lipids of Rhodopseudomonas spheroides.


Incorporation of radioactivity from [me-14C]methionine and [2-14C]glycine into the lipids of Rhodopseudomonas spheroides.


Metabolic turnover of the lipids of Rhodopseudomonas spheroides.


Intracellular location of enzymes in rhodopseudomonas spheroides.


Temperature effects on the formation and reactions of free radicals in gamma-irradiated dry enzymes.


Behavior, hormones, and Hydra. Research on behavior of lower invertebrates may help elucidate some cellular actions of hormones.


Constriction of human umbilical arteries. Interaction between oxygen and bradykinin.


Cardiac actions of glucagon.

Cardiac actions of glucagon.


Retina and optic nerve.

Retina and optic nerve.


Studies on the tyrosine aminotransferase mechanism.


Activation of cow adrenal glucose 6-phosphate dehydrogenase by adrenocorticotropin.


Pyridine-nucleotide coenzymes in bull and rabbit spermatozoa.


Alpha-oxidation of 2-hydroxystearic acid in vitro.


Studies on the mechanism of estrogen biosynthesis. V. Stereochemical comparison of aromatization in placental and microbiological systems.


Ipecac syrup--correct dosage.

Ipecac syrup--correct dosage.


Report on a limited anopheline survey at Ifakara, South-Eastern Tanzania.


On the trypanosome-infection rate of Glossina morsitans in the Ulanga District (Tanzania).


Simple models or simple processes? Some research on clinical judgments.


The electron spin resonance and absorption spectra of microsomal cytochrome P-450 and its isocyanide complexes.


Some properties of an NADH-benzyl viologen reductase from Azotobacter vinelandii.


On the fatty acid and hydrocarbon hydroxylation in rat liver microsomes.


On collagens of invertebrates with special reference to Mytilus edulis.


Swarming and some other habits of Mansonia perturbans and Psorophora ferox (Diptera: Culicidae).


Anticholinergic drug action on pancreatic exocrine outflow in man and dog.


Letter to the Editor: Conference on the epidemiology of periodontal disease.


On the properties of the 12 alpha-hydroxylase in cholic acid biosynthesis. Bile acids and steroids. 198.


Chromatographic resolution of complementary strands of denatured Pneumococcal DNA.


Biological consequences of the replacement of choline by ethanolamine in the cell wall of Pneumococcus: chanin formation, loss of transformability, and loss of autolysis.


In vitro assay of insect hynurenine-3-hydroxylase.


Thioproperazine ("Majeptil"), therapeutic results and complications in 63 patients with functional psychoses.


L-serine dehydratase, DL-threonine aldolase, and D-glucuronate reductase in serum. Effects following experimental liver and kidney damage in the rat.


Cervical pain syndromes.

Cervical pain syndromes.


Blind nasal intubation using doxapram hydrochloride.


ISMS malpractice insurance now in effect.


Thematic techniques and clinical practice.


Lactate dehydrogenase activity in muscle after prolonged severe exercise in man.


Clinical experience with extil.

Clinical experience with extil.


Hemoconcentrating substance and vascular permeability factor from rat kidney lysosomes. Possible involvement of lysosomes in the pathogenesis of cardiovascular diseases.


Different attractiveness of electroluminiscent light to several species of mosquitoes.


Inhibition of steroid delta-4 reductase by heparin: studies with desoxycorticosterone, progesterone, androstenedione and testosterone.


Two different iodinating systems in isolated thyroid cells.


Further consideration of psychosomatic predisposing factors in allergy.


Isolated perfused dog spleen method.

Isolated perfused dog spleen method.


Progressive traumatic aneurysm of the dorsalis pedis artery. A case report.


The Leeuwenhoek lecture, 1967. Teichoic acids and the molecular structure of bacterial walls.


The monolayering in tissue culture of fibroblasts from different sources.


The action of sodium pump inhibitors on neuromuscular transmission.


The influence of internal sodium on the behaviour of motor nerve endings.


Inhibition of lactation in mice following feeding with ergot sclerotia [Claviceps fusiformis (Loveless)] from the bulrush millet [Pennisetum typhoides (Staph and Hubbard)] and an alkaloid component.


Lobster righting responses and their neural control.


Cellular dynamics in the morphogenesis of hydra during bud development and regeneration.


Light-dependent reduction of nicotinamide adenine dinucleotide phosphate by chromatophores of Rhodopseudomonas spheroides.


Effect of alloxan and portacaval shunt on the synthesis of fatty acids and sterols by rat liver.


Reduction of p-nitrobenzoic acid by fishes.


A comparison of progesterone and epinephrine inhibition on the myometrium of the rat.


Resistance to suppression by dexamethasone of plasma 11-O.H.C.S. levels in severe depressive illness. Use of the midnight dexamethasone suppression test showed that the plasma 11-hydroxycorticosteroid (11-O.H.C.S.) level did not undergo its normal reduction in 14 out of 27 patients with severe depression. Resistance to dexamethasone suppression correlated with the clinical rating of the severity of depression, while recovery from depression was associated with return of normal responsiveness to dexamethasone. The explanation of these findings is unknown.


Biosynthesis of sphingolipid bases. II. Keto intermediates in synthesis of sphingosine and dihydrosphingosine by cell-free extracts of Hansenula ciferri.


Detection of simulated MMPI records using the desirability (DY) scales.


The effect of hydrogen ions on the control of mitochondrial respiration.


Oxidation of indene in liver microsomes.


Protection of microbial dihydrofolate reductase against inactivation by pronase.


Effect of adrenergically reactive drugs on peroxisomal enzymes in Tetrahymena.


Czechoslovak Dental Congress.

Czechoslovak Dental Congress.


Antihistamines as local anesthetic agents for allergic patients.


Operation Action: from philosophy to practice.


The bus lecture technique for teaching about life in the city.


Measuring problem-solving skills by means of the simulated clinical nursing problem test.


Purdue's orientation program for new faculty.


Developing an attitude inventory.

Developing an attitude inventory.


A clinical experiment with small children.


The first Metropolitan Regional Convention of the Philippine Dental Association.


Make the next meeting pay off.

Make the next meeting pay off.


Dental disease - a world problem.

Dental disease - a world problem.


Differentiation of a bifid ureter from ureteral diverticula.


Medical progress in the severely affected Rh-sensitized pregnancy.


Seven day utilization of our hospitals.

Seven day utilization of our hospitals.


Abscess of lung.

Abscess of lung.


A case of post-pericardiotomy syndrome: pathogenical consideration.


Coronary artery occlusion with myocardial infarction in a twelve-year-old boy--two episodes with a fatal outcome.


Fusion of the libia minora.

Fusion of the libia minora.


Loss of teeth.

Loss of teeth.


Clinical experience with a new topical corticosteroid, betamethasone 17-valerate.


Community immunity: how, when and how much?


Predicted and unpredicted cross-reactions of an acetylphosphogalactan of Sporobolomyces yeast. The teichoic acid of streptococcal Group N, with end groups of galactose phosphate, had been shown to cross-react with antipneumococcal sera of types VI, XIV, XVI, and XXVII. End groups of D-galactose-1-phosphate in the phosphogalactans of Sporobolomyces yeasts made it predictable that these galactans would precipitate the same antipneumococcal sera and also antisera to streptococcal Group N. The predictions were verified, and other unpredicted reactions were found. Precipitation of much of the antibody in an antipneumoccal type XVIII horse serum was shown to be due to O-acetyl-D-galactose residues in the phosphogalactan, in accord with earlier information that an O-acetyl sugar was a principal determinant of S XVIII. The new results identify this sugar as D-galactose. Since it is linked 1,3- in S XVIII, the O-acetyl group in the Sporobolomyces galactan is probably also on a 1,3-linked residue. Another major cross-reaction in anti-S. paratyphi A serum characterizes the galactose residues in the "O" polysaccharide of the bacillus as members of the D-series probably linked in tandem 1,6-, 1,6-; 1,6-, 1,3-; 1,3-, 1,6-; or 1,3-, 1,3-. Reactions of periodate-oxidized-reduced products confirm the conclusions stated above. Quantitative data are given.


Resuscitation. A Greek panel reports.

Resuscitation. A Greek panel reports.


Rifampicin: a new rifamycin. I. Bacteriological studies.


Effect of hypothermia on antifibrillatory action of pronethalol.


On the mechanism of the sleep-prolonging effect of antimetabolites of nicotinamide.


Dual transmission in the stellate ganglion of the dog.


On the cause of the different sensitivity to antihistaminics (mepyramine) of anaphylactic, histamine, and anaphylatoxin shock.


Some central and peripheral actions of suberyl-di-choline.


Hormonal control of carbohydrate and lipid metabolism and drug induced alterations.


Endodermal cell-types in hydra.

Endodermal cell-types in hydra.


Willing victims: the husbands of paranoid women.


Research on psychosocial adjustment of Indian youth.


A psychopathological reaction precipitated by sensory deprivation.


A system of notation and measurement for space suit mobility evaluation.


Protection against ethanol-induced conditioned necrosis.


Response to treatment of alcoholism. A follow-up study.


Personality in relation to extreme aggression in psychiatric offenders.


Mental symptoms as an aid in the early diagnosis of carcinoma of the pancreas.


Urine indican excretion in malabsorptive disorders.


Short communication: some actions of a benzyl-glucofuranoside on isolated veins.


Dental calculus formation rate in a submarine environment.


Temperature in the monkey: transmitter factors released from the brain during thermoregulation. When perfusate is collected from the anterior hypothalamus of a cooled donor monkey and is transfused to a corresponding hypothalamic site in a normal monkey, fever occurs in this recipient. Conversely, perfusate from a heated donor monkey lowers the recipient monkey's temperature when the same hypothalamic transfusion procedure is followed. These experiments provide direct evidence of a neurochemical "coding" within the specific anatomical region of the brain historically implicated in the control of body temperature.


Luciferins, bioluminescent substances.

Luciferins, bioluminescent substances.


Pulmonary disease of vascular origin.

Pulmonary disease of vascular origin.


Production of antibodies with specificity toward adenosine, uridine, and ribose 5-phosphates.


Functional anatomy of synaptic transmission.


Effect of atropine on acid and pepsin responses to histamine in conscious monkeys.


Further experimental observations on the gastric acid secretion inhibitor SC.15396.


Clinical experiences with beta-adrenergic blocking agents.


Tyrosine synthesis in a Pseudomonas species.


The effect of magnesium pemoline on cognition and behavior.


Conference on preparation for medical education in the traditionally Negro college.


4-oxo-1,2,3,4-tetrahydroquinazolines. I. Syntheses and pharmacological properties of 2-methyl-3-aryl-4-oxo-1,2,3,4-tetrahydroquinazolines and their 1-acyl derivatives.


Report of a three-year clinical trial comparing a toothpaste containing sodium monofluorophosphate with two marketed products.


Clinical comparison of pharmacologic emetics in children.


Deficiency of pneumococcal serum opsonizing activity in sickle-cell disease.


Influence of reserpine and rescinnamine on the spontaneous and evoked sympathetic activity in rats.


The sugars and amino acids "building blocks" in S and R strains of different Brucella Serobiotypes, their cell walls and endotoxins.


Increased excretion of 137Cs in humans by Prussian Blue.


On a quantitative assessment of the Wobble hypothesis for a polynucleotide system.


Tissue NADH levels in the rat brain during pronounced hyperventilation.


Distribution of serotonin in the nervous system of various animal species.


Premature termination of psychotherapy and patient-therapist expectations.


A study of electromyographic findings in patients with progressive muscular dystrophy during remetabolizing therapy.


Gas consumption and growth rate of Hydrogenomonas eutropha in continuous culture. The bacterium Hydrogenomonas eutropha is under consideration for use in a regenerative life-support system for manned space missions of long duration. A 4-liter continuous culture unit containing the organism was operated for a period of 272 days under autotrophic environmental conditions. The best steady-state run achieved with this unit was observed over a 22-day time interval after 181 days of operation. During this time, the culture consumed an average of 22.9 +/- 2.0 ml of carbon dioxide per min, 38.1 +/- 3.3 ml of oxygen per min, and 128.5 +/- 10.6 ml of hydrogen per min. It required 18.7 +/- 1.2 liters of fresh nutrient medium per 24 hr to maintain a constant, preestablished cell population of 1.65 g (dry weight) per liter. The ratio of consumption of carbon dioxide, oxygen, and hydrogen varied from 1:1.2:4.5 to 1:1.9:6.6, with an average of 1:1.7:5.7. Based on these values, approximately 60 liters of the culture would be necessary to balance the gas exchange of one man.


Clinical evaluation of stannous fluoride when used as a constituent of a compatible prophylactic paste, as a topical solution, and in a dentifrice in naval personnel. II. Report of findings after two years.


In vitro antimicrobial activity and human pharmacology of cephaloglycin. Serum and urine concentrations of cephaloglycin (an orally absorbed derivative of cephalosporin C) were determined in normal volunteers and in patients. The in vitro activity of cephaloglycin was also studied. All strains of group A streptococci (Streptococcus pyogenes) and Diplococcus pneumoniae were inhibited by 0.4 mug of cephaloglycin per ml. Eighty per cent of the Staphylococcus aureus strains and about 50% of the Escherichia coli and Proteus mirabilis strains were inhibited by 1.6 mug of cephaloglycin per ml. Klebsiella-Aerobacter species were more resistant to cephaloglycin and 12.5 mug per ml was required to inhibit 70% of these strains. When single doses of 250, 500, or 1,000 mg of cephaloglycin were administered to fasting volunteers, a peak serum concentration of at least 0.5 mug per ml was achieved. A full breakfast did not interfere with absorption of cephaloglycin. Probenecid enhanced both the peak serum concentration and the duration of antibiotic activity in the serum. Serum concentrations of cephaloglycin were even higher in patients who were receiving repeated doses. The peak serum concentrations of cephaloglycin in all volunteers and patients were adequate to inhibit all strains of group A streptococci and D. pneumoniae. Many of the peak serum concentrations were adequate to inhibit some strains of S. aureus, E. coli, and P. mirabilis. Urine levels of cephaloglycin were high enough in all volunteers and patients to inhibit more than 90% of the E. coli and P. mirabilis strains and over 70% of the strains of Klebsiella-Aerobacter.


Comparison of two methods of identifying maladjusted college students.


MMPI computer interpretation for college counseling.


Computer application of MMPI actuarial systems with a college population.


Heterogeneity of rough-surfaced liver microsomal membranes of adult, phenobarbital-treated, and newborn rats. Rough microsomes from the livers of adult, phenobarbital-treated, and newborn rats were subfractionated on a continuous sucrose gradient. Among the subfractions a marked heterogeneity in the distribution patterns of some enzyme activities appears. The isopycnic density of the various fractions in aqueous sucrose ranges from 1.17 to 1.25. The sedimentation coefficients (s(0)) in 0.25 M sucrose lie between 0.4 x 10(3) S and 1.2 x 10(3) S. In adult animals, the NADH- and NADPH-cytochrome c reductase as well as the G6Pase activities are much higher in the slower sedimenting fractions than in the pellet. The increase in the level of G6Pase induced by fasting as well as the phenobarbital-induced changes are most prominent in the slowly sedimenting fractions. Three injections of phenobarbital have no effect on the specific NADPH-cytochrome c reductase activity in the pellet, but cause a significant increase of this enzyme activity in the light fractions. In the newborn animal, the NADH-ferricyanide reductase and NADPH-cytochrome c reductase activities are highest in the light fractions. On the other hand, the amount of cytochrome b(5) is evenly distributed in all cases. Short-term incorporation of leucine-(14)C and glycerol-(3)H in vivo after phenobarbital treatment shows contrasting results, as the former is increased and the latter is decreased in the slowly sedimenting fractions. Leucine-(14)C incorporation into isolated, total membrane proteins is greater in both phenobarbital-treated and newborn animals than in untreated adults. The data support a multistep model for membrane biogenesis and indicate dynamic and individual behavior of the different parts of the rough-surfaced endoplasmic reticulum.


Personal differences in perceptual deprivation.


Responses of the superficial limb veins of the dog to changes in temperature.


Danger of perilymph loss during microsurgery of the ear. Considerations based on an experimental study in the cat.


Cytochemical and ultrastructural observations on the argentaffin and argyrophil cells of the gastro-intestinal tract in mammals, and their place in the APUD series of polypeptide-secreting cells.


The Norrköping fluoridation study.

The Norrköping fluoridation study.


Practice of medicine in hospitals.

Practice of medicine in hospitals.


Myocardial infarction during pregnancy.

Myocardial infarction during pregnancy.


Report of a case with an unusual complication. Cystic fibrosis of the pancreas.


Neurogenic claudication.

Neurogenic claudication.


Illinois medicine-a century ago.

Illinois medicine-a century ago.


Medical progress in the care of subdural hematomas in infants and children.


Results in an ubran private psychiatric practice.


Medical management of obese people: timely observations.


Histochemical studies on some respiratory enzymes in muscular phase of trichinellosis.


Coexisting viral (respiratory syncytial) and bacterial (pneumococcus) otitis media in children.


Some unusual mutants of a locus related to the am locus in Neurospora.


Metabolic pathways for nitrate reduction in Escherichia coli.


Morphoea (circumscribed scleroderma or Addison's keloid).


Electron transport enzymes in guinea-pig tissues under scorbutic condition.


"No-growth"-complementation in forced heterokaryons from sorbose-resistant (transport-defective) Neurospora crassa mutants.


On the distribution of O-seryl-N-acetylgalactosaminide glycosidase and N-acetyl-beta-D-hexasaminidase in vertebrates and invertebrates.


Some immunochemical characteristics of sea urchin gametes.


Studies on the structure of ribosomal ribonucleic acid from normal and tumour tissues.


Copper replacement of magnesium in the chlorophylls and bacteriochlorophyll.


Photocoagulation and other therapy for histoplasmic choroiditis.


Changes in laboratory values with butaperazine.


Activities of NADPH-linked electron transport system in tumor-bearing rats.


Disseminated sclerosis syndrome following antirabic vaccination.


Systematic oscillations in tyrosine transaminase and other metabolic functions in liver of normal and adrenalectomized rats on controlled feeding schedules.


Influence of dietary protein levels and hydrocortisone administration on the branched-chain amino acid transaminase activity in rat tissues.


Tyrosine toxicity in the rat: effect of high intake of p-hydroxyphenylpyruvic acid and of force-feeding high tyrosine diet.


Dietary regulation of pyruvate kinase synthesis in rat liver.


Reinforcement schedule, intertrial activity, and verbal operant conditioning.


Allosteric inhibition of TPN-linked isocitrate dehydrogenase by folate.


The use of fluoride dentifrices in the control of dental caries: methodology and results of a clinical trial.


Factors affecting the premature induction of tyrosine aminotransferase in foetal rat liver. 1. Premature delivery of foetal rats by uterine section results in the rapid appearance of tyrosine aminotransferase activity in foetal liver, after an initial lag period of 3-6hr. 2. The premature induction of activity is completely repressible by actinomycin D given soon after delivery and partially repressible by puromycin and amino acid analogues. 3. Glucagon injections into foetal rats in utero lead to production of tyrosine aminotransferase in the foetal liver, but adrenalin and nor-adrenalin are without effect. 4. Injections of glucose, galactose, fructose and mannose into prematurely delivered rats repress the development of tyrosine aminotransferase activity about 50% when they are given 2hr. after delivery, but glucose has no significant effect when injected at delivery. 5. The results are discussed in relation to current hypotheses on the role of hormones in enzyme induction in foetal development.


Hexokinase activity in the preimplantation mouse embryo.


Induction of hepatic tryptophan pyrrolase and tyrosine transaminase by histones and other polypeptides.


Noradrenaline depleting and blood pressure lowering activity of threo-corbadrine.


Pharmacological investigations of the extract of piper peepuloides (roxb.).


Demographic and prognostic characteristics of psychiatric patients classified by gross MMPI measures.


Item ambiguity and item discrimination in the MMPI.


Prediction of the standard MMPI scale scores from 71 items: the mini-mult.


Enzymes of fructose metabolism in human liver. The enzyme activities involved in fructose metabolism were measured in samples of human liver. On the basis of U/g of wet-weight the following results were found: ketohexokinase, 1.23; aldolase (substrate, fructose-1-phosphate), 2.08; aldolase (substrate, fructose-1,6-diphosphate), 3.46; triokinase, 2.07; aldehyde dehydrogenase (substrate, D-glyceraldehyde), 1.04; D-glycerate kinase, 0.13; alcohol dehydrogenase (nicotinamide adenine dinucleotide [NAD]) substrate, D-glyceraldehyde), 3.1; alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate [NADP]) (substrate, D-glyceraldehyde), 3.6; and glycerol kinase, 0.62. Sorbitol dehydrogenases (25.0 U/g), hexosediphosphatase (4.06 U/g), hexokinase (0.23 U/g), and glucokinase (0.08 U/g) were also measured. Comparing these results with those of the rat liver it becomes clear that the activities of alcohol dehydrogenases (NAD and NADP) in rat liver are higher than those in human liver, and that the values of ketohexokinase, sorbitol dehydrogenases, and hexosediphosphatase in human liver are lower than those values found in rat liver. Human liver contains only traces of glycerate kinase. The rate of fructose uptake from the blood, as described by other investigators, can be based on the activity of ketohexokinase reported in the present paper. In human liver, ketohexokinase is present in a four-fold activity of glucokinase and hexokinase. This result may explain the well-known fact that fructose is metabolized faster than glucose.


Cognitive sensitivity to aversive maternal stimulation in late-adolescent males.


Smoking behavior in offspring of heart disease patients: a response to cognitive dissonance.


Adaptation of Rhodopseudomonas spheroides.


Models of the evolution of dominance.

Models of the evolution of dominance.


Vanadium and other metals in ascidians.

Vanadium and other metals in ascidians.


Silicon compounds in biological systems.


A discussion on anomalous aspects of biochemistry of possible significance in discussing the origins and distribution of life. Introduction.


Reversible suspension of metabolism and the origin of life.


Fitting the environment by modifying water structure.


The occurrence and metabolism of carbon--halogen compounds.


Fringe biochemistry among microbes.

Fringe biochemistry among microbes.


The limits of microbial existence.

The limits of microbial existence.


Histochemical and biochemical aspects of iodine binding in the tunic of the ascidian, Dendrodoa grossularia (van Beneden).


The effects of psychotropic drugs on psychological testing.


Prevention of the acute ethanol-induced fatty liver by antihistamines and stimulants of hepatic microsomal enzyme activity.


An evaluation of two procedures used in the study of p-nitrobenzoic acid metabolism by rat liver.


Discrimination among temporal patterns of stimulation in a computer model of a coelenterate nerve net.


Three cases of testicular tumours.

Three cases of testicular tumours.


Caries prevalence in children of low income families.


Personality characteristics of patients with chronic obstructive pulmonary emphysema.


The biosynthetic L-alpha-glycerol phosphate dehydrogenase of E. coli.


Identical initial steps during transformation for high and low efficiency markers in Diplococcus pneumoniae.


The dermal light sense.

The dermal light sense.


Purification and properties of a disulfide reductase obtained from Achromobacter starkeyi.


Nonspecific supersensitivity of the guinea-pig ileum produced by chronic ganglion blockade.


The effect of dihydroxyphenylalanine, pheniprazine and dextroamphetamine on the in vivo release of dopamine from the caudate nucleus.


An erythromycin-resistant pneumococcus.

An erythromycin-resistant pneumococcus.


The ecology of the soldier in World War II.


Enzymatic 7-beta-hydroxlation of 3-beta-hydroxychol-5-enoic acid.


Acid carboxypeptidases: their occurrence in plants, intracellular distribution and possible function.


The effect of daily apple consumption on dental caries experience, oral hygiene status and upper respiratory infections.


DOM (STP), a new hallucinogenic drug, and DOET: effects in normal subjects.


False adrenergic transmitters.

False adrenergic transmitters.


Respiration of Lactobacillus casei.

Respiration of Lactobacillus casei.


Mouth protectors: a progress report. Bureau of Dental Health Education.


Correlated changes of some enzyme activities and cofactor and substrate contents of pea cotyledon tissue during germination. 1. The activities of six enzymes (hexokinase, phosphoglucose isomerase, phosphofructokinase, aldolase, glucose 6-phosphate dehydrogenase and amylase) in extracts of pea cotyledons were determined. The activities during the first 10 days after germination showed individual and characteristic changes that indicate a specific control of both synthesis and destruction of enzymes. 2. Tissue contents of glucose, inorganic phosphate, glucose 6-phosphate, fructose 6-phosphate, ATP, ADP, AMP, NAD and NADP were also determined, and a correlation is reported between the substrate concentrations at day 1 and the subsequent enzymic activity. 3. The initial NAD(+)/NADH ratio value of 1 changed to about 3 by day 4; the NADP content was lower and changes in the oxidation state were less striking. The ratio of ATP to ADP and AMP remained virtually constant.


Newer steroids in nonviral encephalitis.


Humoral factors in bronchoconstriction.

Humoral factors in bronchoconstriction.


Encephalitis: a variable syndrome in response to viral infection.


Succinylcholine-hexafluorenium combination for muscular relaxation: a reappraisal.


What can we learn from Latin America? II. Preparing nutritionist-dietatians for integrated health services.


Diuretic properties of furosemide in renal disease.


Mecloprodin (Tavegyl)--a new antihistamine: clinical trials in Australia 1966-1967.


Metabolism of infarcted heart muscle during tissue repair.


Gastric mucosal blood flow and acid secretion in conscious animals measured by heat clearance.


Experimental transmission of Chandipura virus by mosquitoes.


Seizure threshold, adrenalectomy and sodium-potassium stimulated ATPase in rat brain.


Spastic dysphonia. I. Voice, neurologic, and psychiatric aspects.


Bioluminescence assay: principles and practice.


Progestins biosynthesis in rats in vivo following infusion of cholesterol-7-alpha-3H and acetate-1-14C into luteinized ovaries.


Acyanotic congenital heart disease.

Acyanotic congenital heart disease.


On the ion transport system of photosynthesis--investigations on a molecular level.


The structures and stereochemistry of majdine and isomaydine.


Influence of hydrocortisone on the histone pattern in rat thymus.


Significance of testicular biopsies in cryptorchidism in children.


Christopher Columbus and the history of syphilis.


Cofactor requirements for the conversion of cholesterol sulfate to pregnenolone sulfate by a submitochondrial system from bovine adrenal ortex.


The problems of dental development among the children on a Greek island.


Avulsion perineal injury. A case report of avulsion of skin of penis and scrotum.


Electron microscopic study of tissue culture cells infected with measles virus.


Reaction of several saccharides with Japanese encephalitis virus.


Some factors influencing the rate of photodynamic inactivation of bacteriophages with acridine orange.


Biosynthesis and metabolism of catecholamines.


Comparison of genetic properties of influenza viruses before and after repeated passages in monkey kidney cell culture.


Potentiation of the antiviral activity of interferon by histones.


Propagation of type A Myxovirus influenzae in diploid cell strain WI-38. I. Adaptation experiments with strains of human and animal origin.


Persistent infection of mosquito cells grown in vitro with Murray Valley encephalitis and Japanese encephalitis viruses.


The multiplication of Middleburg s and 1 plaque viruses in Aëdes aegypti mosquitoes.


Histological picture in the place of inoculation and in lymph nodes of mice after subcutaneous infection with tick-borne encephalitis virus.


Experimental inhalation infection of germ-free piglets with vaccinia virus.


Influence of hydroxylamine and beta-propiolactone on the kinetics of plaque growth of SP3 and SP8 phages of Bacillus subtilis.


Comparative studies on the selective inhibiting effect of benzazole compounds on virus multiplication. I. Effects on benzthiazole compounds on the multiplication of influenza and parainfluenza 1 viruses in vitro.


Morphology of small and large plaque variants of the Blacksburg strain of Newcastle disease virus.


Hamster interferons induced by polyoma virus.


Induction of interferon activity in mouse serum by phase I Coxiella burneti antigen.


Plaque method and immunofluorescence in studies on the isolation of tick-borne encephalitis virus from tick vectors.


Treatment of experimental tick-borne encephalitis in mice with amiphenosine (5-(p-aminophenyl) cytosine).


Interactions of polynucleotides and their components. IV. Acid denaturation of polyadenylic-polyuridylic complexes.


On the state of chlorophyll in vivo.

On the state of chlorophyll in vivo.


Denaturation fo DNA.

Denaturation fo DNA.


The splitting of 2-thiouracil by a pyrimidineless Escherichia coli.


The effects of quinidine, ajmaline, papaverine and adrenergic beta-receptor inhibitors in experimental BaCl2-arrhythmia developed for the quantitative assay of antiarrhythmic drugs.


Biting mosquitoes (Diptera, Culicinae) found in the Baltic coastal area between the Vistula and Odra mouths, in the years 1963--1965.


Effect of pH on the resistance of pneumococci to streptomycin.


Relations between structures of three K polysaccharides of Escherichia coli and cross-reactivity in antipneumococcal sera.


Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. I. Inhibition by amino acids of the enzymes in threonine biosynthesis.


Abnormal fissions in dimethyl sulphate treated hydras.


Strabismus.

Strabismus.


A survey of dental caries in Iceland.

A survey of dental caries in Iceland.


The anatomical site distribution of clinical dental caries in the maxillary incisor teeth of 11- and 12-year-old children.


Report on a dental survey among the school population of French Polynesia. Population surveyed and numbers of teeth present.


The roles of reduced nicotinamide-adenine dinucleotide phosphate in steroid hydroxylation.


Sports-medicine in the world today.

Sports-medicine in the world today.


A case of sulthiame overdosage.

A case of sulthiame overdosage.


Influence of hypoxia, glucocorticoid, and endotoxin on hepatic enzyme induction.


Effect of hypophysectomy and growth hormone on the inductions of rat liver tyrosine aminotransferase and tryptophan oxygenase by hydrocortisone.


Factors affecting anaerobic glycolysis in mouse and rat liver and in Morris rat hepatomas.


Radioprotective effect of magnesium pemoline: a comparison with pemoline and dextroamphetamine.


Ulcerative colitis and erythrocyte G6PD deficiency. Salicylazosulfapyridine-provoked hemolysis.


Progesterone metabolism in twins: progesterone biosynthesis in placenta in vitro.


Double-blind controlled trial of lucidril (meclofenoxate) in the post-traumatic syndrome, especially dizziness.


Behavior of two states of the ethyl isocyanide compound of reduced P-450 in oxidation-reduction cycle.


Dual effect of ethyl isocyanide on drug hydroxylation by liver microsomes.


The twenty-first World Health Assembly--May 1968.


Histochemical method for the demonstration of the activity of phosphoglucomutase.


Histoenzymology of the developing human basal ganglia.


Laboratory studies with the mosquito iridescent virus (MIV).


Fungal pathogens of mosquitoes in New Zealand. I. Coelomomyces opifexi sp. n., on the mosquito Opifex fuscus Hutton.


Failure of fluoridation in Chile. A critical analysis after eleven years.


Compounds related to pemoline. 2-amino-5-aryl-4-oxo-2-oxazolines.


Reduction of cinnamic acid to cinnamaldehyde and alcohol.


Relationship between self-acceptance and adjustment, repression-sensitization and social competence.


Psychopathology and guilt in heterosexual and subgroups of homosexual reformatory inmates.


The influence of cyclophosphamide on some hydrolases and oxidizing enzymes in the livers and kidneys of mice.


Carbon dioxide control for manned spacecraft.


Microbiological evaluation of a typical suit loop heat exchanger during manned testing.


Insensible weight and water loss during simulated space flight.


The automated assay of complete enzyme reaction rates. II. Digital readout and data processing of linear rates.


Studies on sepiapterin reductase: further characterization of the reaction product.


Melanin pigmentation.

Melanin pigmentation.


The comparative toxicity of DDT and analogues to susceptible and resistant houseflies and mosquitos. Studies of the comparative toxicity of more than 120 DDT analogues to susceptible and insecticide-resistant houseflies (Musca domestica L.) and mosquitos (Culex fatigans Wiedemann and Anopheles albimanus Wiedemann) have shown that the relative effectiveness of these compounds against DDT-resistant insects is correlated with the susceptibility of the molecule to attack by DDT-ase at the benzylic hydrogen. Compounds highly effective against DDT-resistant flies and mosquitos are produced by blocking this detoxication mechanism by o-chlorination, alpha-fluorination, and by altering the aliphatic portion of the molecule as in the nitropropyl, neopentyl, dichlorocyclopropyl, and trichlorobenzanilide derivatives. These compounds offer practical possibilities for the control of DDT-resistant insects. The correlation of structure, DDT-like activity, and resistance ratios gives new insight into the mode of action of DDT and the nature of DDT resistance.


A nutrition study of school children in a depressed urban district. II. Physical and biochemical findings.


Relationships between visual skills and behavior disorders.


Studies on the experimental gastrointestinal ulcers produced by reserpine and stress. II. Ulcerogenic activities of reserpine and its analogues.


Pharmacological properties of the proteolytic products of the liver homogenates of rat by the acidic protease (TE-P), isolated from Trametes sanguinea.


Electroshock, liver serotonin level and tryptophan pyrrolase activity in rats.


Studies on uptake and decarboxylation of histidine by isolated rat mast cells.


Fourteen- and six-per-second positive spikes in a nonclinical male population.


Investigation of interferometry for the analysis of enclosed habitable atmospheres. AMRL-TR-66-236.


Identification of volatile contaminants of space cabin materials. AMRL-TR-67-58.


Research and development of a waste management unit for a manned space vehicle. AMRL-TR-67-2.


A system to analyse water for potability. AMRL-TR-67-123.


Speec in an artificial atmosphere (44 per cent oxygen-56 per cent helium). AMRL-TR-66-165.


Effects of minimal personal hygiene and related procedures during prolonged confinement. AMRL-TR-66-146.


The potential hazard of Staphylococci and Micrococci to human subjectes in a life support systems evaluator with elevated cabin temperature. AMRL-TR-67-43.


The development of a turbine-driven circulating blower for manned aerospace enclosures. AMRL-TR-67-126.


Studies on the acute toxicity and mechanisms of action of compounds PFG and R. AMRL-TR-66-214.


Immobilized liquid membrances for continuous carbon dioxide removal. AMRL-TR-67-53.


Regenerative carbon dioxide adsorption system using charcoal. AMRL-TR-67-48.


The biochemical, physiological, and metabolic evaluation of human subjects wearing pressure suits and on diet of precooked freeze dehydrated foods. AMRL-TR-67-8.