Studies on the metabolism of diethyl 4-nitrophenyl phosphorothionate (parathion) in vitro. 1. The metabolism of the phosphorothionate parathion in vitro was examined by using [(32)P]parathion and microsomes isolated from the livers of various animal species. 2. The major metabolic products of parathion in this system in vitro were identified as diethyl 4-nitrophenyl phosphate (paraoxon), diethyl hydrogen phosphate, diethyl hydrogen phosphorothionate and p-nitrophenol. 3. The reaction leading to the formation of diethyl hydrogen phosphorothionate and p-nitrophenol requires the same cofactors (NADPH and oxygen) required for metabolism of parathion to its active anti-acetylcholinesterase paraoxon. 4. The enzyme activity towards parathion per unit weight of liver is increased some 65-130% by pretreatment of male rats with phenobarbital and 3,4-benzopyrene. 5. The metabolism of parathion is inhibited by incubation in a nitrogen atmosphere and in an atmosphere containing carbon monoxide. Pure oxygen is also inhibitory. These results are discussed in terms of a deficiency of oxygen for maximal activity as well as the lability of some component of the system to oxidation.


The comparative biochemistry of developing Ascaris eggs. VII. Malate oxidation and metabolism in unembryonated eggs.


The diagnosis and treatment of cerebral concussion.


Tissue compatibility in regenerating explants from the colonial marine hydroid Hydractinia echinata (Flem.).


Semiautomatic interpretation of the MMPI.


MMPI study of three types of delinquents.


Differential endorsement of MMPI F scale items by psychotics and behavior disorders.


Correlation of three MF measures for males.


An abbreviation of the social introversion scale for 373-item MMPI.


An attempt to develop a process-reactive scale for the MMPI.


MMPI related behavior in a student nurse group.


Dual actions of some N-(1-phenylethyl)guanidines on the nictitating membrane of conscious cats.


Clinicians' decisions as a basis for deriving actuarial formulae.


Infrared studies of hydantoin and its derivatives.


Rhodexin A and rhodexoside in Ornithogalum umbellatum.


Observations on isoprenaline-induced myocardial necroses.


Impurities in halothane: their identities, concentrations and determination.


The bioassay of gamma-aminobutyric acid using a muscle preparation from Ascaris lumbricoides.


Diffusion from gelatin-glycerin-water gels.


Desipramine and amphetamine metabolism.

Desipramine and amphetamine metabolism.


Quantitative determination of physostigmine in solution.


Calcium-dependent stimulating action of triiodothyronine on the isolated muscle of the frog.


A simple flow recorder.

A simple flow recorder.


A new nerve muscle preparation: the obturator nerve-anterior gracilis preparation in the rat.


Antagonism of morphine analgesia by reserpine and alpha-methyltyrosine and the role played by catecholamines in morphine analgesic action.


The effect of hemicholinium on the depletion of catecholamine induced by reserpine.


The anti-nialamide effect of pantothenic acid and pyridoxine.


Tissue histamine and catecholamines in the reparative process.


Cyproheptadine (Periactin) for allergic and pruritic dermatoses.


Antimicrobial cold remedies.

Antimicrobial cold remedies.


Metabolite-promoted heat lability of beta-galactosidase and its relation to catabolite repression.


Sterile blood cultures in bacterial endocarditis.


A GABA-related hypothesis on the mechanism of action of the antimotion sickness drugs.


Absorption, distribution and metabolism of the anthelmintic methyridine.


Hydroxylation of cinchophen by microsomal enzymes.


Effect of reserpine and pronethalol on the therapeutic and toxic actions of digitalis in the dog heart-lung preparation.


The action of 2-amino-tetralin (beta-tetrahydronaphthylamine) on the metabolism of 5-hydroxytryptamine in the brain of the mouse.


The detection and estimation of bradykinin in the circulating blood.


Congenital malformations in Israel.

Congenital malformations in Israel.


Clinical evaluation of the analeptic, doxapram, in dogs and cats.


A quantitative analysis of the antagonism of intravenous noradrenaline by thymoxamine or phentolamine on the blood pressure of the conscious cat.


The isolation of enzymically active nuclei from the rat heart and uterus.


Methaemoglobin formation induced by aromatic amines and amides.


A method for the quantitative determination of the total concentration of radiopaque agents in plasma.


A note on a series of decamethylenebis[(4-substituted amino)quinaldinium] salts with potent antibacterial properties.


Effects on the reproductive organs of feeding the non-ionic surfactant Triton X-100 to mice.


A polarographic limit test for sulphoxide in chlorpromazine.


The mechanism of the tranquillizing action of asarone from Acorus calamus Linn.


The effect of succinylcholine on the isolated retractor bulbi muscle of the cat.


The presence of peroxidases in tragacanth.


The accumulation of [3H]noradrenaline in the adrenergic nerve fibres of reserpine-treated mice.


Chlorpromazine-lysergic acid diethylamide antagonism.


Polyhedral emulsion particles.

Polyhedral emulsion particles.


Some pharmacological activities of crotonosine and pronuciferine.


"Indirect" sympathomimetic effects of L(+)-isomers and desoxy derivatives.


Rubrine C, a pharmacologically active alkaloid from Phoradendron rubrum.


Adamantanamines and their derivatives as sensitizing agents for 5-hydroxytryptamine-induced contraction of smooth muscle.


Phenylethyldithiocarbamate: a new dopamine-beta-hydroxylase inhibitor.


Activity correlations and the mode of action of aminoalkylphenothiazine tranquillizers.


Regulation, purification, and some properties of the NAD-specific glutamate dehydrogenase of Neurospora.


Effect of monoamine oxidase inhibitors and some related compounds on lipid metabolism in rat. Plasma free fatty acids and lipoprotein lipase of the heart and adipose tissue.


Purification and some properties of cholesterol 20-alpha-hydroxylase from hog adrenal mitochondria.


Polarized inhibitory control of regional differentiation during regeneration in Tubularia. 3. The effects of grafts across sea water-agar bridges in electric fields.


Electroencephalographic and psychometric studies of Indoklon convulsive treatment and electroconvulsive treatment. (A preliminary report).


A contribution to the evolution of collagen.


Uptake and storage of catecholamines in rabbit brain after chronic reserpine treatment.


Adrenoceptive receptors in the duodenum, aorta and atria of the rabbit.


The mechanism of the inhibition of dehydrogenases by salicylate.


Blockade of bradykinin-induced nociception in the rat as a test for analgesic drugs with particular reference to morphine antagonists.


The excretion of [14C] butylated hydroxytoluene in the rat.


Histamine release from the mast cells of guinea-pig lung.


The biliary metabolites of butylated hydroxytoluene in the rat.


Comparative study of nine variables for Seventh-Day Adventist and non-Adventist teenagers.


Mode of action of methyldopa.

Mode of action of methyldopa.


The stereospecificity of noradrenaline uptake by cat atria.


Inhibition of noradrenaline uptake by angiotensin.


The effect of (+-)-p-chloroamphetamine on the susceptiblity to seizures and on the monoamine level in brain and heart of mice and rats.


Central hypotensive effect of alpha-methyldopa.


Reversal of alpha-methyltyrosine-induced behavioural depression with dihydroxyphenylalanine and amphetamine.


Inhibitory responses to transmural stimulation in isolated intestinal preparations.


The micellar properties of some non-ionic surface-active agents in polar solvents.


The interaction of dexamphetamine with inhibitors of noradrenaline biosynthesis in rat brain in vivo.


Qualitative and quantitative tests for doxapram hydrochloride.


Daily rhythmic changes in tyrosine transaminase activity of the rat liver.


Rates of photosynthesis by isolated chloroplasts.


Inactivation of vaccinia virus by gamma radiation.


Mode of hemolytic action of the antifungal polyene antibiotic filipin.


Gas exchange of algae. 3. Relation between the concentration of carbon dioxide in the nutrient medium and the oxygen production of Chlorella pyrenoidosa. The oxygen production of a photosynthetic gas exchanger containing Chlorella pyrenoidosa (1% packed cell volume) was measured when various concentrations of carbon dioxide were present within the culture unit. The internal carbon dioxide concentrations were obtained by manipulating the entrance gas concentration and the flow rate. Carbon dioxide percentages were monitored by means of electrodes placed directly in the nutrient medium. The concentration of carbon dioxide in the nutrient medium which produced maximal photosynthesis was in the range of 1.5 to 2.5% by volume. Results were unaffected by either the level of carbon dioxide in the entrance gas or the rate of gas flow. Entrance gases containing 2% carbon dioxide flowing at 320 ml/min, 3% carbon dioxide at 135 ml/min, and 4% carbon dioxide at 55 ml/min yielded optimal carbon dioxide concentrations in the particular unit studied. By using carbon dioxide electrodes implanted directly in the gas exchanger to optimize the carbon dioxide concentration throughout the culture medium, it should be possible to design more efficient large-scale units.


Activity of selected penicillins in vitro and in experimental bacterial infections in mice. The minimal inhibitory concentration and the 50% mouse protective dose for five key penicillins are presented. Such data provide a useful guide in evaluating the activity of new penicillins, in comparison with those already commercially available, and establishes the amounts of antibiotic necessary to obtain a PD(50) for several experimental model infections in mice.


Photooxidation and reduction of cytochrome-552 and NADP photoreduction by Euglena chloroplasts.


Antagonism in the simultaneous oxidation of D-amino acids by D-amino acid oxidase.


Effect of nucleic acids on KB and Ehrlich ascites tumor cells.


Accumulation of norepinephrine in rat tissue following treatment with three beta-adrenergic antagonists.


Study of the biphasic response of the dog's iris to nerve stimulation.


Effects of 48/80 or reserpine on tissue antihistamine extracts.


Acute pancreatitis during pregnancy and the puerperium.


Routine detection and identification in urine of stimulants and other drugs, some of which may be used to modify performance in sport.


Infrared identification of pharmaceutically important sulphonamides with particular reference to the occurrence of polymorphism.


Histidine decarboxylase in the stomach of the rat.


The configuration of beta-eucaine and beta-isoeucaine.


Noradrenaline-phospholipid interactions.


Apparatus for studying the disintegration of tablet coatings.


Influence of nicotine on the coronary circulation of the isolated heart of the cat.


A note on a micro and a semimicro method for the assay of ephedrine.


Localization of 5-hydroxytryptamine uptake in rat brain after intraventricular injection.


Fenfluramine and critical flicker frequency.


Isolation, aggressiveness and brain 5-hydroxytryptamine turnover.


Disulfiram and some effects of amphetamine in mice and rats.


The concentration of adrenaline and noradrenaline in the brain and the heart of the goldfish, Carassius auratus.


Antagonistic action of vitamin D2 on noradrenaline-induced lipolysis in vitro.


Assignment of absolute configurations to receptor sites and drugs.


Tracing the changes in capillary permeability during rat anaphylaxis.


Addiction. Cases treated on a psychiatric service.


Toxicity of pesticides to man: risks from present levels.


Effects of pesticides on wildlife.

Effects of pesticides on wildlife.


Importance of pesticides in preventive medicine.


The importance of pesticides in Indian food production.


The importance of pesticides in British food production.


Possible new and more selective means of pest control.


Pesticides: present levels in food and possible sources of contamination.


The repair of x-ray damage to the deoxyribonucleic acid in Micrococcus radiodurans: a study of the excision process.


Inherited defects in dogs and cats in Australia.


The inhibition of malate, tricarboxylate and oxoglutarate entry into mitochondria by 2-n-butylmalonate.


Genetic and biochemical studies of nitrate reduction in Aspergillus nidulans. 1. In Aspergillus nidulans nitrate and nitrite induce nitrate reductase, nitrite reductase and hydroxylamine reductase, and ammonium represses the three enzymes. 2. Nitrate reductase can donate electrons to a wide variety of acceptors in addition to nitrate. These artificial acceptors include benzyl viologen, 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride, cytochrome c and potassium ferricyanide. Similarly nitrite reductase and hydroxylamine reductase (which are possibly a single enzyme in A. nidulans) can donate electrons to these same artificial acceptors in addition to the substrates nitrite and hydroxylamine. 3. Nitrate reductase can accept electrons from reduced benzyl viologen in place of the natural donor NADPH. The NADPH-nitrate-reductase activity is about twice that of reduced benzyl viologen-nitrate reductase under comparable conditions. 4. Mutants at six gene loci are known that cannot utilize nitrate and lack nitrate-reductase activity. Most mutants in these loci are constitutive for nitrite reductase, hydroxylamine reductase and all the nitrate-induced NADPH-diaphorase activities. It is argued that mutants that lack nitrate-reductase activity are constitutive for the enzymes of the nitrate-reduction pathway because the functional nitrate-reductase molecule is a component of the regulatory system of the pathway. 5. Mutants are known at two gene loci, niiA and niiB, that cannot utilize nitrite and lack nitrite-reductase and hydroxylamine-reductase activities. 6. Mutants at the niiA locus possess inducible nitrate reductase and lack nitrite-reductase and hydroxylamine-reductase activities. It is suggested that a single enzyme protein is responsible for the reduction of nitrite to ammonium in A. nidulans and that the niiA locus is the structural gene for this enzyme. 7. Mutants at the niiB locus lack nitrate-reductase, nitrite-reductase and hydroxylamine-reductase activities. It is argued that the niiB gene is a regulator gene whose product is necessary for the induction of the nitrate-utilization pathway. The niiB mutants either lack or produce an incorrect product and consequently cannot be induced. 8. Mutants at the niiribo locus cannot utilize nitrate or nitrite unless provided with a flavine supplement. When grown in the absence of a flavine supplement the activities of some of the nitrate-induced enzymes are subnormal. 9. The growth and enzyme characteristics of a total of 123 mutants involving nine different genes indicate that nitrate is reduced to ammonium. Only two possible structural genes for enzymes concerned with nitrate utilization are known. This suggests that only two enzymes, one for the reduction of nitrate to nitrite, the other for the reduction of nitrite to ammonium, are involved in this pathway.


The phospholipids of Pneumococcus I-192R, A.T.C.C. 12213. Some structural rearrangements occurring under mild conditions. 1. The phospholipids from the non-capsulated strain of Pneumococcus I-192R, A.T.C.C. 12213, were separated into three fractions by chromatography on columns of silicic acid and DEAE-cellulose (acetate form). 2. The water-soluble phosphate esters produced by deacylation of each fraction were separated by chromatography on columns of DEAE-cellulose (HCO(3) (-) form). 3. Three deacylated products, diglycerol phosphate, glycerylphosphorylglycerol phosphate and bis(glycerylphosphoryl)glycerol, were identified by analysis, by chemical degradations and by comparison with synthetic materials. 4. From a study of freshly isolated lipids prepared and worked up under conditions where exposure to acid was minimal, it was concluded that the Pneumococcus contains phosphatidylglycerol and bisphosphatidylglycerol, in the molar proportion 1:2.5-3.0, and that the deacylation product glycerylphosphorylglycerol phosphate was probably an artifact of the isolation procedure. 5. Acid-catalysed isomerization (phosphodiester migration) of diglycerol phosphate and bis(glycerylphosphoryl)glycerol and transesterification (glycerol phosphate transfer) of diglycerol phosphate were observed. The structures of the products were established by degradation. 6. A novel mechanism for the biosynthesis of bisphosphatidylglycerol is presented.


The metabolism of phenylacetic acid by a Pseudomonas.


Fluorescence technique to demonstrate creatine phosphokinase isozymes.


Foods for astronauts.

Foods for astronauts.


The status of oral health in cerebral palsy children and their siblings.


Some aspects of the dynamics of oxidation-reduction of etiocholanolone-3-3H,4-14C in man.


Evaluation of topical applications of stannous fluoride to teeth of children born and reared in a fluoridated community: interim report.


Performance tests of amnesic patients with cylert.


Molecular interactions of caffeine with o-, m- and p-iodobenzoic acids and o-, m- and p-fluorobenzoic acids.


Steroidal monoquaternary ammonium salts with non-depolarizing neuromuscular blocking activity.


Some pharmacodynamic effects of the babesicidal agents quinuronium and amicarbalide.


Viscosity of phospholipid sols.

Viscosity of phospholipid sols.


Degraded and undegraded carrageenans and experimental gastric and duodenal ulceration.


Haemorrhagic, traumatic and tourniquet shock in the rat.


Uncoupling of oxidative phosphorylation by glycyrrhetic acid, fusidic acid and some related triterpenoid acids.


Interaction of aspirin with urea in water.


Development of resistance to the lowering of plasma free fatty acids induced by pyrazole derivates.


The influence of 5-hydroxytryptamine on the actions of adrenaline.


Influence of cannabis, tetrahydrocannabinol and pyrahexyl on the linguomandibular reflex of the dog.


Effect of tyramine on the atrium and the papillary muscle of the immunosympathectomized rat.


Hexamethonium potentiation of noradrenaline-induced contractions in the dilatator pupillae of the cat.


Protamine-induced hypocalcaemia in rats.


A positive inotropic effect of phenylephrine mediated through alpha adrenergic receptors.


Accumulation of tritiated 5-hydroxytryptamine in brain slices.


The toxicity of alpha-dihydroheptachlor and related compounds to the housefly (M.domestica L.) and their metabolism by housefly and pig liver microsomes.


Resistance to urea as a genetic marker of some animal and human viruses.


Formation of influenza virus components as revealed by the fluorescent antibody technique.


Investigations on the course of influenza virus infection in chick embryo cells.


The combined effect of influenza virus and x-rays on the metabolism of nucleic acids in mouse lung cells.


Peculiarities of the antiviral action of dibenzylphosphinic acid.


Effect of multiplicity of infection on the rate of protein synthesis in encephalomyocarditis virus-infected L cells.


Role of lysozyme and character of antibodies in experimental viral infection.


The effect of Escherichia coli endotoxin on virus infectivity.


Comparative studies with the Zilber (Carr) strain of Rous sarcoma virus (Z-RSV). I. Response of chicken embryo fibroblasts to infection with Z-RSV.


Action of some chemical and physical factors on SD and T-2 bacteriophages.


Isolation and characterization of parainfluenza-3 virus from Egyptian water buffaloes.


Replication of Rickettsia prowazeki in L-cells as revealed by immunofluorescence.


Plaque assay of rubella virus on a stable rabbit cornea cell line.


An interferon like substance induced by mannans.


Investigations on glycogen kinetics in experimental herpes simplex infection.


Genetic factors determining the chromatographic behaviour of tick-borne encephalitis virus propagated in chick embryos.


Cytopathic activity of the extraneural variant of Tahyna virus in the GMK cell line.


A simple method for concentration of coxsackie virus from water.


Further studies on 20-alpha-hydroxysteroid dehydrogenase of rat testes.


Antagonizing action of chlorpromazine, dibenamine, and phenoxybenzamine on potassium-induced contraction.


The effect of N-(4-diethylamino-2-butynyl)-succinimide (DKJ 21) on oxotremorine induced hypothermia in the rat.


Centrally mediated cardiovascular responses to isoprenaline.


Observations on intraventricular hemicholinium-3-induced EEG seizures.


Fluoridated salt used in dental research project in Colombia. Controlled study conducted in remote Andes mountain site.


Clinical anticaries effect of repeated topical sodium fluoride applications by mouthpieces.


Ferredoxin and photosynthetic phosphorylation.


The neutropenic (pancytopenic?) type of bacillary dysentery.


Caries increments, tooth discoloration, and state of oral hygiene in children given single annual applications of acid phosphate-fluoride and stannous fluoride.


Comparison of drug-metabolizing and olefin-forming systems in rat liver.


Further studies on the Xavante Indians. VII. The oral status of the Xavantes of Simões Lopes.


An analysis of the mechanism of catecholamine effects on coronary circulation.


Pharmacologic properties of a slobber-inducing mycotoxin from Rhizoctonia leguminicola.


Treatment of bacterial endocarditis in patients with penicillin hypersensitivity.


Stimulatory effect of tolazoline on smooth muscle.


Objections to MMPI items.

Objections to MMPI items.


Humoral factors affecting pulmonary inflation during acute anaphylaxis in the guinea-pig in vivo.


MMPI patterns of overt male homosexuals: reinterpretation and comment on Dean and Richardson's study.


Demonstration of separate adrenergic and cholinergic fibres to the vessels of the rear quarters of the rat by hemicholinium and a proposed role in peripheral vascular regulation.


On MMPI high-point codes of homosexual versus heterosexual males.


Personality factor in divorce.

Personality factor in divorce.


Sex differences and the relationship between the Marlowe-Crowne Social Desirability Scale and MMPI indexes of psychopathology.


The Edwards SD Scale: a measure of adjustment or of dissimulation?


The medial neurosecretory cells and egg maturation in mosquitoes.


The biosynthesis of dihydrosphingosine in cell-free preparations of Hansenula ciferri.


The isolation of Cache Valley virus from mosquitoes in Jamaica.


An adrenergic control system in Tetrahymena.


Study on the cinchophen detoxication and its relationship to ulcerogenesis.


Studies of flavin-adenine dinucleotide-requiring enzymes and phenothiazines. 3. Inhibition kinetics with highly purified D-amino acid oxidase.


Effects of starvation and refeeding on the oxidation of drugs by liver microsomes.


The influence of certain psychotropic drugs on the biosynthesis of liver proteins in vivo.


Some cultural and ultrastructural aspects of Smittium culisetae (Trichomycetes) from mosquito larvae.


Laboratory and clinical studies of a new antibiotic, cephaloridine, in the treatment of gram-positive infections.


Postganglionic sympathetic nerve innervating human fallopian tube.


A check list of the Culicine mosquitos of Tanganyika, with notes on their distribution in the territory.


Larvae of Culicine mosquitos in north Iraq (Diptera, culicidae).


Hydroxylation of gamma-butyrobetaine to carnitine in rat liver.


The treatment of herpes simplex and zoster with Terramycin.


The treatment of iron-deficiency anaemia of pregnancy.


Iron-deficiency anaemia.

Iron-deficiency anaemia.


Group practice.

Group practice.


An experiment with an ECG machine in the surgery of a general practitioner.


An experiment in general practioner-psychiatrist co-operation.


Back to Darwin.

Back to Darwin.


The effects of methoserpidine and cyclopenthiazide upon elevated arterial pressure.


A diagnostic work-study index. A use of the E-book to measure work load in relation to morbidity.


Learning and teaching by family doctors (James Mackenzie).


Open access--a general practitioner's right?


Cervical cytology in general practice.

Cervical cytology in general practice.


Description of a Scottish rural practice 1965.


The international conference on tetanus, Bern, Switzerland, July 1966.


The structure of depression, by factoring Q-data, in relation to general personality source traits.


Detailed study of contaminant production in a space cabin simulator at 760 mm of mercury.


Prolonged recording from single vestibular units in the frog during plane and space flight, its significance and technique.


Isolation and properties of plastocyanin from Anabaena variabilis.


The relationship of cyclic and non-cyclic electron flow patterns with reduced indophenols to photophosphorylation.


Wavelength-dependent quantum yields of chloroplast phosphorylation catalyzed by phenazine methosulphate.


Immunological changes in animals exposed to low sulphur dioxide concentrations.


ATP formation coupled to photosynthetic NADP+ reduction with artificial electron donors.


Wavelength-dependent quantum yield of ATP synthesis and NADP reduction in normal and dichlorodimethylphenylurea-poisoned chloroplast.


Psychologic characteristics of psychiatric patients having pain as a presenting symptom.


Motor convulsions and EEG during maximal electroshock in the rat.


Daedalus and Icarus revisited: interpersonal aspects of flight instruction.


Some effects of progesterone and related steroids on the central nervous system.


Psychological factors in flying fatigue.


The use of normative data in the psychological evaluation of flying personnel.


Changes in D(--)-beta-hydroxybutyric dehydrogenase activity during brain maturation in the rat.


D-amino acid oxidase. I. Spectrophotometric studies.


Metabolism of the phenylalanine hydroxylation cofactor.


MMPI item changes by college students under ideal-self response set.


Comparison of selected experimental MMPI profiles of sexual deviates and sociopaths without sexual deviation.


Ecological studies during Project Sealab II. A sand-bottom community at depth of 61 meters and the fauna attracted to "Sealab II" are investigated.


Purification and some characteristics of an alpha,beta-unsaturated ketone reductase from dog erythrocytes and human liver.


Polyarteritis nodosa in a four-month-old infant; case report, with autopsy findings.


Circadian rhythms of liver enzymes and their relationship to enzyme induction. Tyrosine alpha ketoglutarate transaminase, which is rapidly induced by various agents, shows circadian rhythmicity in the intact rat. This rhythmicity is only slightly altered after adrenalectomy, indicating that adrenal hormones do not play a major role in the metabolic control of the activity of tyrosine alpha ketoglutarate transaminase. On the other hand, phenylalaninepyruvate transaminase, which is not inducible over the same time period, does not show circadian variation. The results suggest that the sensitivity of an enzyme's regulating system to inducing agents may be related to the inherent circadian rhythm of the enzyme.


Tyrosine transaminase induced by cycloheximide.


Histology of the cryptorchid testis.

Histology of the cryptorchid testis.


Purification of 5,10-methylenetetrahydrofolate dehydrogenase from Salmonella typhimurium and its inhibition by purine nucleotides.


The pupation rhythm in Aedes taeniorhynchus (Diptera: Culicidae). I. Introduction.


Studies on the pathogenesis of meningitis. VI. Antagonism between penicillin and chloramphenicol in experimental pneumococcal meningitis.


Sixteen personality factor profiles of collegiate wrestlers.


Arteriovenous fistula complicating percutaneous renal biopsy in polyarteritis nodosa.


Statistical evaluation of the action of three different respiratory analeptics on pulmonary ventilation.


A simple technique for splinting displaced anterior teeth in children.


Aerospace medicine. Ours and theirs.

Aerospace medicine. Ours and theirs.


Modification of transmitter release by electrical interference with motor nerve endings.


The release of acetylcholine from nerve endings by graded electric pulses.


An investigation of some properties of endothelium related to capillary permeability.


The frequency of nerve action potentials generated by applied currents.


Tetrodotoxin and neuromuscular transmission.


Necrotizing arteritis in a newborn infant.


The longest dimension.

The longest dimension.


One year's experience in a laminar flow room.


Humoral mechanisms of anaphylaxis in white mice.


The state of the art. Design of high bay clean rooms.


Antihistamines and other allergy aids.

Antihistamines and other allergy aids.


Observations on testicular descent.

Observations on testicular descent.


Early ocular manifestations of periarteritis nodosa.


Medicare.

Medicare.


Hazards of radiation in obstetrics and gynecology.


This case report was part of Surgical Grand Rounds held at Chicago Wesley Memorial Hospital on March 26, 1966. Case presentation. Pulsating tumors of the sternum.


Tubal pregnancy: a review of 91 cases.

Tubal pregnancy: a review of 91 cases.


Progress in the treatment of emphysema.

Progress in the treatment of emphysema.


Sarcoidosis of the heart associated with myocarditis: report of case.


Non-criminal forensic pathology.

Non-criminal forensic pathology.


Fetal distress: lessons of the fetal electrocardio-gram.


Practical points in diagnosis and treatment of pigmented lesions.


Regeneration time in irradiated hydras.

Regeneration time in irradiated hydras.


Descending column of cells in hydra.

Descending column of cells in hydra.


Coral caused keratosis?

Coral caused keratosis?


Clinical evaluation of butaperazine (AHR 712).


Psychological implications of cryptorchism.


A modified Unna boot for the treatment of foot injuries.


Individual responses and social desirability.


A study of the doctor-patient relationship using randomly selected cases.


Mycoplasma pneumoniae in general practice. Clinical and epidemiological  studies during an outbreak lasting nine months in a rural community.


Immunization in general practice (an analysis of some of the factors involved).


Exfoliative vaginal cytology.

Exfoliative vaginal cytology.


A diabetic survey in a Suffolk rural practice.


The rheology of some oil-in-water emulsions stabilized by condensed complex films.


Influence of dextrose on the viability of Bacillus subtilis.


Replenishment by 5-hydroxytryptophan of the amine stores in the central 5-hydroxytryptamine neurons after depletion induced by reserpine or by an inhibitor of monoamine synthesis.


The effects of posterior pituitary hormones on isometric tension and isotonic shortening of the pig myometrium.


Acetylcholine in extracts and perfusates of urinary bladder.


Degraded and undegraded carrageenans and antipeptic activity.


A modification of a method for the evaluation of topical anaesthesia in the earthworm.


Mechanism of the vasoconstrictor action of isoprenaline on an isolated artery preparation.


The effect of differing reserpine pretreatments on the cardiovascular response to tyramine.


The influence of blood pressure on the responses of the nictitating membrane of the cat to sympathetic stimulation.


Potentiation of noradrenaline isomers by cocaine and desipramine in the isolated vas deferens of the rat.


The subcellular binding of propranolol in rat heart.


Failure of dopamine to accumulate in central noradrenaline neurons after depletion with diethyldithiocarbamate.


Brain dopamine and the amphetamine-reserpine interaction.


Occurrence of a cardiac heteroside in Bersama yangambiensis.


A simple method for measuring the amount of azovan blue exuded into the skin in response to an inflammatory stimulus.


Effect of anticoagulants on the capillary resistance of internal organs of rats.


The metabolism of tyramine-H3 in different regions of the CNS.


Fractures, with special reference to fractures of the ankle and foot.


Interaction between liver microsomes and compounds capable of undergoing enzymic hydroxylation.


Injuries to the foot.

Injuries to the foot.


Dermatomyositis induced by drugs.

Dermatomyositis induced by drugs.


Continuous suppressive antimicrobial treatment in chronic infected bronchitis during the winter months.


Fulminant ulcerative colitis with a normal rectum.


Antral activity and symptom periodicity in duodenal ulceration.


Myocardial infarction or pulmonary embolus?


Meprobamate intoxication treated with peritoneal dialysis.


Malrotation of the intestine, volvulus and gangrene with survival.


Wounds and injuries of the kidney.

Wounds and injuries of the kidney.


The early diagnosis and treatment of allergic asthma.


The ileoptomists of Chicago.

The ileoptomists of Chicago.


The municipal tuberculosis sanitarium population changes.


Results of a double-blind clinical study of a new anticholinergic agent as an axillary antiperspirant.


Preoperative and postoperative use of pentazocine, a new non-narcotic analgesic.


Placenta localization using radioiodinated--131 human serum albumin.


Recent progress in the management of Rh isoimmunization.


Modification by physostigmine of response to ganglion stimulant drugs.


Acetylcholine release from the cat superior cervical ganglion by carbachol.


Intracellular disposition of H3-morphine in the brain and liver of nontolerant and tolerant guinea pigs.


Bacterial-viral interrelations in respiratory infections of children.


Reduced nicotinamide adenine dinucleotide phosphate in the liver of X-ray irradiated rats.


Auto-potentiation and potentiation by inhibition of monoamine oxidase of the sympathomimetic action of phenelzine and pheniprazine.


Evaluation of sympathetic beta-receptor blockade by recording the rate of ventricular pressure rise in cats.


Nineteenth century anticipation--twentieth century realization.


A method of stimulating the complete sympathetic outflow from the spinal cord to blood vessels in the pithed rat.


Man's inheritance.

Man's inheritance.


Prescribing of chloramphenicol and aplastic anaemia.


Renal function and age.

Renal function and age.


The problem of pregnancy termination on psychiatric grounds.


Brucellosis in general practice.

Brucellosis in general practice.


Terminal care units.

Terminal care units.


Some oxidative enzymes and cytochrome in the specific granules of neutrophile leukocytes.


Management of thyrotoxic crises with a beta-adrenergic blocking agent (Pronethalol).


The role of isocitrate lyase in the metabolism of algae.


Tissue binding of noradrenaline.

Tissue binding of noradrenaline.


The flow of organic and inorganic materials through the alimentary tract of the sheep.


Organization of the primate retina: electron microscopy.


The influence of diet on the nitrogenous components passing to the duodenum and through the lower ileum of sheep.


Some physico-chemical properties of salicylazosulphapyridine, including its solubility, protolytic constants and general spectrochemical and polarographic behaviour.


Determination of salicylazosulphapyridine by polarography.


The susceptibility of pneumococci to eight antimicrobial agents.


Birth order and MMPI patterns.

Birth order and MMPI patterns.


Chemical structure of light chains: amino acid sequence of type K Bence-Jones proteins.


The specificity of antigenic recognition of antibody heavy chain.


Chemical structure of light chains.

Chemical structure of light chains.


Chemical studies of the combining sites of antibodies.


The genetic control of immunoglobulin synthesis.


The genetics of the immune response.

The genetics of the immune response.


Biosynthesis of immunoglobulins on polyribosomes and assembly of the IgG molecule.


Sexual attitudes of medical students: some implications for medical education.


The effect of dimethyl sulfoxide (DMSO) on antibiotic sensitivity of a group of medically important microorganisms: preliminary report.


Aging and psychopathology: some MMPI evidence for seemingly greater neurotic behavior among older people.


The problem of male infertility.

The problem of male infertility.


The action of dopamine on neurones of the caudate nucleus. 1. Dopamine applied iontophoretically to neurones of the caudate nucleus of cats caused excitation of some (9% of those encountered) and depression of others (60%). Some cells have been found affected both by dopamine and by acetylcholine.2. The effects of dopamine could be prevented by the previous iontophoretic administration of phenoxybenzamine, but not by dichloroisopropylnoradrenaline.3. Responses evoked in caudate neurones by electrical stimulation of substantia nigra were depressed by dopamine. No evidence for enhancement of the effects of nigral stimulation through the application of dopamine were detected.4. Stimulation of nucleus centromedianus thalami depressed firing of caudate neurones.5. The hypothesis that dopamine may act as an inhibitory synaptic transmitter within the caudate is put forward.


International Association for Dental Research. 45th general meeting, Washington, D. C., March 16-19, 1967.


Pharmacological studies on antagonists against nicotine-induced convulsions and death.


Voyeurism and exhibitionism.

Voyeurism and exhibitionism.


Electroencephalographic changes during brief periods of perceptual deprivation.


The development of beta adrenergic blocking drugs: a retrospective and prospective evaluation.


Evaluation of the cardiac effects of several beta adrenergic blocking agents.


The influence of adrenergic mediators and their structural analogs on cardiac actomyosin systems.


Adrenergic mechanisms in cardiac glycogen metabolism.


A neural action of pronethalol.

A neural action of pronethalol.


The mechanism of the lipolytic action of catecholamines.


The effects of the catecholamines, adrenergic blocking agents, prostaglandin E1, and insulin on cyclie AMP levels in the rat epididymal fat pad in vitro.


Studies on the inhibition of insulin action in vitro by beta adrenergic blocking agents.


Histochemical evaluation of NADP-dependent glucose-6-phosphate and isocitrate dehydrogenases in steroid producing organs and tumors.


Appraisal of the effects of catecholamines on cardiac electrical activity.


Regulation of methaemoglobinaemia in horse and human erythrocytes.


On the use of nicotinamide in assays for microsomal mixed-function oxidase activity.


An effect of histamine on the nictitating membrane of the cat: potentiation of the actions of adrenaline, noradrenaline and acetylcholine.


Effects of tetrodotoxin on innervated smooth muscle preparations.


The analysis of species specific variations in form and growth pattern in Hydra.


Substance Q: a smooth muscle contracting substance liberated from human plasma lipids by the action of heat.


Observations on the discovery of a dorso-ventral axis in Hydra.


Solubility and viscosity relations in the system ascorbic acid--water--polysorbate 80.


Influence of chronic phenobarbitone treatment on uterine phosphofructokinase induction.


Human chorionic gonadotropin (HCG).

Human chorionic gonadotropin (HCG).


Effect of hemocholinium on the number of synaptic vesicles.


Spectral studies of drug interaction with hepatic microsomal cytochrome.


Corticosteroids in cardiovascular disorders.


The testes of the cryptorchid ram.

The testes of the cryptorchid ram.


The Twelfth (1966) Interim Scientific Session of the American Rheumatism Association.


Differences in MMPI scores in native and nonnative Alaskans.


Influence of socioeconomic background on the scores of some MMPI scales.


Personality correlates of inner- and other-direction.


Studies on the toxicity of copper. I. The toxic action of copper in vivo and in vitro.


Studies on the toxicity of copper. II. The behaviour of microsomal membrane ATPase of the pigeon's brain tissue to copper and some other metallic substances.


Actions of cupric salts on isolated cerebral tissues.


Effect of nerve stimulation on the noradrenaline content of the spleen.


Regulation of ovulation rate after removal of one ovary in mice.


The isolation of poly-alpha-L-glutamic acid from the oviduct of the domestic fowl.


Hybrid cells from mouse and man: a study.


A theory of the mode of growth of fungi in the form of pellets in submerged culture.


The Chicago conference on Clinical Training and Clinical Psychology at Teachers College.


Standardizing for economy in clean room design and construction. A study in costly variations.


IBM mobile room lends flexibility to Apollo Saturn unit fabrication.


Dental caries increments evaluated by use of bite-wing roentgenograms.


Ectopic testis--a content of direct hernia (a case report).


Management of alveolar fractures.

Management of alveolar fractures.


The peduncle lobe: a visuo-motor centre in octopus.


The effects on locomotion of lesions to the visuo-motor system in octopus.


The accumulation of noradrenaline in constricted sympathetic nerves as studied by fluorescence and electron microscopy.


Monocular fixation in human eye movement.


Natural selection and feeding speed in a blood-sucking insect.


Inotropic and chronotropic effects of a series of beta-adrenergic blocking drugs: some structure-activity relationships.


Absence of adrenocortical stress responses in experimental pyelonephritis.


Protection against histamine shock by catecholamines in Bordetella pertussis-treated, adrenalectomized, or adrenergic blocked mice.


Reproductive and immunological characteristics of a strain of Aedes aegypti selected for resistance to gamma radiation.


Glossary of chromosomal and genetic terms.


Diastrophic dwarfism.

Diastrophic dwarfism.


Benign teratoma of the tongue.

Benign teratoma of the tongue.


The varied attitudes of anti-obesity therapy.


Obstetric hemorrhage.

Obstetric hemorrhage.


Falls in infancy and their prevention.

Falls in infancy and their prevention.


A-V fistula.

A-V fistula.


Influence of test-taking attitudes on personality inventory scores.


Characteristics of participants and nonparticipants in individual test-interpretation interviews.


Some intellectual correlates of schizoid indicators: WAIS and MMPI.


Lesions of the scrotum.

Lesions of the scrotum.


The Croonian lecture, 1966. The genetic code.


Relationship between chemical structure and biological activity of hen egg-white lysozyme and lysozymes of different species.


On the conformation of the hen egg-white lysozyme molecule.


Crystallographic studies of the activity of hen egg-white lysozyme.


The mechanisms of hydrolysis of glycosides and their revelance to enzyme-catalysed reactions.


The chemical structure of lysozyme substrates and their cleavage by the enzyme.


The binding and cleavage by lysozyme of N-acetylglucosamine oligosaccharides.


Lysozyme as a transferase.

Lysozyme as a transferase.


Possible hydrolytic mechanisms.

Possible hydrolytic mechanisms.


A crystallographic study of the oxidation of lysozyme by iodine.


An interaction between lysozyme and penicillin.


Inhibition of lysozyme by positively charged groups in the mucopeptide of the bacterial cell wall.


Factors affecting the susceptibility of bacterial cell walls to the action of lysozyme.


Relation between penicillin and N-acetylmuramic acid in the binding site of lysozyme.


Psychometric and rated anxiety.

Psychometric and rated anxiety.


"Acquiescence" in the MMPI: a method variance artifact?


Further evidence concerning acquiescence and the MMPI.


measurement of pilot fatigue.

measurement of pilot fatigue.


Cofactor induced synthesis of D-glucose-6-phosphate: NADP oxidoreductase in  the uterus.


Pregnanolone: a highly potent, naturally occurring hypnotic-anesthetic agent.


The arteriographic diagnosis of periarteritis nodosa.


Verbal productivity as a measure of change in affective status.


Hormonal factors altering rhythmicity of tyrosine-alpha-ketoglutarate transaminase in rat liver.


Subjective correlates of clinically manifested anxiety and depression.


Polyglandular endocrine adenomatosis presenting as hyperaldosteronism. Patient presents unusual combination of multiple endocrine adenomata, peptic ulcer, and aldosteronism.


Ecological factors in the 1963 outbreaks of western encephalitis in Saskatchewan.


A sexual influence on the biosynthesis and storage of L-ascorbic acid in rats.


Therapeutic studies in "therapy resistant" schizophrenic patients.


Doctor shortage.

Doctor shortage.


Election results significant for physicians.


Toxic megacolon.

Toxic megacolon.


Case presentation. Unusual bladder tumor.


Differential diagnosis of inflammation of the optic nerve head.


Progress in electronic cardiology.

Progress in electronic cardiology.


ISMS refuses to extend contract for military dependents' medical care.


The use of perphenazine syrup in the severely disturbed mentally retarded child.


Radiation hazard and radiology in the operating room.


MMPI scores of juvenile deliquents adjusting to institutionalization.


Behavioral validation of a dominance-submission scale.


An appraisal of the Illinois State Medical Society by its members.


Case presentation: pseudocyst of pancreas.


Migratory thrombophlebitis. Heparin sodium vs. warfarin sodium therapy.


Sulfacetamide sodium in inflammatory ophthalmic disorders. Evaluation in the treatment of 51 patients.


Wine, tranquility and the physician.

Wine, tranquility and the physician.


Mosquito ecology. Report of a WHO Scientific Group.


Low humidity water-retention ability in Eretmapodites chrysogaster and Aedes albopictus.


Pharmacologic adjuncts to the management of shock.


Neuroglial cells: physiological properties and a potassium mediated effect of neuronal activity on the glial membrane potential.


Noradrenaline storage and release in the decentralized spleen.


The vascular circulation in the brain, optic lobes and thoracic ganglia of the crab Carcinus.


Syrup of Ipecac in acute poisoning.

Syrup of Ipecac in acute poisoning.


False antibiotic resistance due to penicillinase.


Antihistaminic activity of dichloroisoproterenol.


Underwater life support.

Underwater life support.


Case presentation: glossopharyngeal neuralgia.


Needless blindness from senile cataracts.


Fiedler's myocarditis and heart block with scar tissue injury of septal nerves.


Toxic epidermal necrolysis. (The scalded skin syndrome).


Dysmenorrhea and pre-menstrual tension in adolescents.


A case report. Schistosomiasis.

A case report. Schistosomiasis.


Allergy and the pregnant woman.

Allergy and the pregnant woman.


Recent advances in the treatment of cancer.


Review of recent changes in anesthesiology.


The ecology of Psorophora confinnis (Diptera: Culicidae) in Southern California. II. Temperature and development.


The first international conference on equine infectious diseases.


Plastic and reconstructive surgery.

Plastic and reconstructive surgery.


The use of psycho-active drugs in children.


Disorders of ocular motility.

Disorders of ocular motility.


Lipid metabolism in brain injury.

Lipid metabolism in brain injury.


Lymphosarcoma of the mediastinum.

Lymphosarcoma of the mediastinum.


Dilemma in the medical department.

Dilemma in the medical department.


Traumatic neuroses and post traumatic syndromes.


What physicians should know about bank charge cards.


Leiomyoma of the sigmoid colon with perforation into the retroperitoneal space.


Opinions and reports on medical ethics.

Opinions and reports on medical ethics.


Clinical evaluation of butaperazine.

Clinical evaluation of butaperazine.


Relationships between social history factors and psychiatric symptoms.


The K factor as a (validity) suppressor variable in predicting success in selling.


The anaemias: classification and investigation.


Anemia in general practice. Laboratory services.


Childhood anaemias in general practice.

Childhood anaemias in general practice.


Anemia in general practice. The general practitioner's point of view.


The person before the disease.

The person before the disease.


The advantages of the associat e degree nursing program.


A faculty undertakes a major curriculum revision.


Nursing management of a patient with cerebral aneurysm.


Successful electroconvulsive therapy in an adrenalectomized patient with endocrine adenomatosis.


Asymptomatic megacolon persisting six years after toxic dilatation of the colon. Report of a case.


Effect of long-term treatment with an anticholinergic drug on gastric secretion in rats.


Studies on the alkaloid content of cultivated ipecac.


Quantitative histochemistry of microscopic structures of the cochlea. II. Ischemic alterations of levels of glycolytic intermediates and cofactors in the organ of corti and stria vascularis.


A trial of dimethothiazine in general practice.


General structure and heterogeneity of immunoglobulins.


Medical quackery.

Medical quackery.


Congestive heart failure and complete heart block: treatment with a permanent transvenous catheter pacemaker.


Blastomycosis of lung.

Blastomycosis of lung.


Blood alcohol levels in vehicular and pedestrian fatalities in Illinois.


Vertigo from a neurosurgical viewpoint.

Vertigo from a neurosurgical viewpoint.


Ocular aspects of vertigo.

Ocular aspects of vertigo.


ISMS symposium on medical implications of the current abortion law in Illinois.


ISMA symposium on medical implications of the current abortion law in Illinois.


Current abortion laws.

Current abortion laws.


The epidemiology of rubella.

The epidemiology of rubella.


A guide to medicare--public aid claims forms by the Division of Public Relations and Economics, Illinois State Medical Society.


The past and future of maternity services.


Days of our years.

Days of our years.


Observations on breast feeding. Why don't women breast feed?


Basic elements in the process of psychotherapy: a research study.


A rapid method for identification of the pneumococcus in the office laboratory.


Screening for galactosemia and glucose-6-phosphate dehydrogenase deficiency in newborn infants.


Wandering spleen with torsion of pedicle. Report of a case with multiple congenital anomalies.


Social desirability, prediction equation, regression equations, and intrinsic response bias.


Pain syndromes. The use of nerve block in diagnosis and treatment. There are four distinct pain entities which may be treated by injection of local anesthetic or neurolytic agents. These entities are somatic, visceral, sympathetic mediated and myofascial pain. Each entity should be recognized as separate from other types of pain and the appropriate therapeutic approach prescribed.


Roentgenologic diagnosis of cryptorchism.


The prune belly syndrome.

The prune belly syndrome.


Congenital absence of abdominal muscles: report of 6 cases.


Hypoxia in modern pressurized jet aircraft.


A phenothiazine with antihistaminic properties.


Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.


Studies on the nature of the chloroplast lamella. I. Preparation and some properties of two chlorophyll-protein complexes.


Brief behaviour therapy for the general practitioner.


The practice of endodontics: past, present, and future.


Oxidative enzyme activity in macroglia and axons of cat optic nerve.


An analysis of the sympathomimetic effects of acetylcholine of the rat ileum.


A two-year comparison of three topical fluoride agents.


Experiments on man.

Experiments on man.


Time and cost factors to provide regular, periodic dental care for children in a fluoridated and nonfluoridated area: progress report. II.


Standardization in human cytogenetics.

Standardization in human cytogenetics.


Round table conference on tavegyl (HS 592).


A simplified method for measuring the volume of extracellular fluid by radioactive sulfur (S35): observations on shifts of fluid in induced hypotension.


Incorporation of tritiated uridine into KB cells infected with parainfluenza 3 virus.


The effects of sympathetic stimulation and epinephrine on the superior rectus muscle of the cat.


Welcome address.

Welcome address.


On the mechanism of action of interferon on the early stage of vaccinia virus reproduction.


Role of free cells in the lymph and blood vessels during viraemia in animals experientally infected with tick-borne encephalitis virus. I. Virus bound in vivo to free lymph node cells in mice.


Study of the virulence of tick-borne encephalitis virus. VI. Intracerebral infection of monkeys with clones experimentally attenuated virus.


Role of free cells in the lymph and blood vessels during viraemia in animals experimentally infected with tick-borne encephalitis virus. II. Virus bound in vivo to the cellular blood component in mice.


Bacteriological investigations of a periapical infection.


Comparative studies with the Zilber (Carr) strain of Rous sarcoma virus (Z-RSV). II. Antigenic relationships and cyst producing capacity in newborn rats.


Specific complement-fixing antibodies against polyoma tumour antigens and viral haemagglutination inhibiting antibodies in hamsters infected with polyoma virus.


Persistent infection of heteroploid and diploid cells with plaque variants of Newcastle disease virus.


Plaque formation by NWS influenza virus in a human diploid cell strain.


Brain mucolipids in experimental rabies.


Persistent infection of a human diploid cell strain with tick-borne encephalitis virus.


Study of the interfering activity of fixed rabies virus in various cell systems.


Synthesis of uridine diphosphate L-rhamnose by enzymes of Chlorella pyrenoidosa.


Enzymic incorporation of deoxyribonucleotides into deoxyribonucleic acid by mammalian testis.


The role of the phagocyte in host-parasite interactions. VII. Di- and triphosphopyridine nucleotide kinetics during phagocytosis.


Stimulation of glucose oxidation by liver homogenates with hexose 6-phosphates.


Studies of a homoserineless bradytroph of Neurospora crassa: demonstration of an altered aspartate beta-semialdehyde dehydrogenase.


Evolution of hydrogen gas from nicotinamide nucleotides by Proteus vulgaris.


Psychological correlates of behaviour in seriously delinquent juveniles.


A fluorescent complex between steroids and nucleotide coenzymes.


Soluble NADP-linked dihydroorotate dehydrogenase from a pseudomonad.


Whose experience?

Whose experience?


Clinical studies with propericiazine (R.P. 8909).


Compounds affecting the central nervous system. IV. Substituted 2-benzyl-3-dialkylaminoalkylindenes and related compounds.


The relationship between defense preference and response to free association.


Hostility on the TAT as a function of defensive inhibition and stimulus situation.


Underachievement in college men: evaluation of the psychodynamics.


Influence of increased gravitational stress on the adaptation of cardiovascular and pulmonary function to exercise.


An enzymic method for the measurement of inorganic phosphate.


Magnetic and spectrophotometric properties of the microsomal carbon monoxide binding pigment.


Mitochondrial forms of glucose 6-phosphate dehydrogenase and 6-phosphogluconic acid dehydrogenase in rat liver.


Adrenergic receptors on some organs.

Adrenergic receptors on some organs.


Anti-fibrillatory action of pronethalol and its modification by reserpinization and norepinephrine infusion.


Antagonism of intravenous histamine in the guinea pig by piperidyl-alkyl-trifluoromethylphenothiazines and trifluoperazine.


Modification of adrenergic responses by antazoline and mepyramine.


p-Phenylenediamines as electron donors for photosynthetic pyridine nucleotide reduction in chromatophores from Rhodospirillum rubrum.


Pigeon liver malic enzyme. IV. Pyruvate reductase activity of the crystalline enzyme.


On a new antigen in virus-infected cells.


Formation of antiviral antibodies by lymphoid cells transferred to a newborn recipient.


The morphological characterisation of respiratory syncytial virus by a simple electron microscope technique.


Studies of an inhibitor of RNA polymerase appearing in virus-infected cells. I. Effect of the inhibitor on the activity of RNA polymerase from Escherichia coli in vitro.


On the importance of the s marker in differentiation of attenuated and non-attenuated strains of measles virus.


Dynamics of immunofluorescence and infectivity of parainfluenza 3 virus in susceptible cells.


Microscopic fluorescence-photometry of virus multiplication in cell cultures.


The influence of ultraviolet light on the kinetics of plaque growth of Bacillus subtilis phages SP 3 and SP 8.


Ocular lesions in relapsing polychondritis and other rheumatoid syndromes.


Efficiency of methods used to destroy influenza inhibitors found in canine sera.


In vivo investigations on viral inclusions of the Kazakhstan strain of tobacco mosaic virus in tissue cultures and free living cells.


Experimental infection of Pitymys subterraneus with tick-borne encephalitis virus.


The effect of inoculum concentration on virus multiplication in cucumber cotyledons. I. Lucerne mosaic virus.


Precipitating antibody response of guinea pigs to respiratory syncytial virus.


The importance of goats in the maintenance tick-borne encephalitis virus in nature.


The role of sialidase in influenza virus infection.


Study of the biological activity of adenoviruses in tissue cultures.


Inactivation of rinderpest and ECBO viruses by hydroxylamine.


Persistence of tick-borne encephalitis virus in, and its transmission by Haemaphysalis spinigera and H. turturis ticks.


Persistence of tick-borne encephalitis virus in nymphs and adults of Ixodes arboricola and its transmission to white mice.


Therapeutic effect of adamantanamine aerosol in experimental influenza infection of white mice.


Isolation of infectious nucleic acid from coxsackievirus A11.


Species insusceptibility in viral hepatitides.


Indirect haemagglutination test with tick-borne encephalitis virus.


Contaminant control in space cabins: approach and results.


Effect of a space cabin environment on viral infection.


Lactate dehydrogenase isoenzymes in rat small intestinal mucosa, liver, kidney and serum, during the administration of cinchophen.


The activities of rat liver alanine, aspartate and tyrosine aminotransferases during the administration of cinchophen.


Cephalexin, a new orally absorbed cephalosporin antibiotic. A new antibiotic, structurally related to cephaloglycin, has been assigned the generic name cephalexin, 7-(D-alpha-amino-alpha-phenylacetamido)-3-methyl-3-cephem-5-carboxylic acid. In vitro antimicrobial activity of cephalexin does not equal that of cephaloglycin. However, excellent oral absorption and lack of serum binding of cephalexin compensates significantly for the lower in vitro activity. Exceptional efficacy against experimental bacterial infections in mice was obtained with cephalexin therapy as compared with cephaloglycin, tetracycline, and chloramphenicol. The data suggest that cephalexin merits clinical trial.


The ferroprotein component of a methylene hydroxylase.


Occurrence and metabolism of scylloinositol in the locust. 1. scylloInositol has been identified as a component of locust haemolymph, where it occurs in concentrations of 0.2-0.4mg./ml. 2. A simple method for the identification of scylloinositol is described. This has been used to demonstrate the presence of scylloinositol in five other insect species. 3. Locust phospholipids contain myoinositol but no scylloinositol. 4. Radioactivity from [(14)C]glucose is incorporated into myoinositol and scylloinositol by the locust in vivo. 5. Extracts of locust fat body catalyse the conversion of myoinositol into scylloinositol. This seems to take place by a two-step process in which myoinositol is first oxidized with NAD(+) to myoinosose-2, and the myoinosose-2 is stereospecifically reduced with NADPH to scylloinositol.


Inhibition of histamine-N-methylation by some antihistamines.


Adrenocorticotrophin-induced changes in the steroidogenic activity of adrenal cell-free preparations.


Relationship of P700, electron spin resonance signal, and photochemical activity of a small chloroplast particle obtained by the action of Triton X-100.


Fluorescence of the subchloroplast particles obtained by the action of Triton X-100.


An NADP reductase, an NADH-dye reductase and a non-haem iron protein isolated from a facultative photoheterotroph, Rhodopseudomonas palustris.


Yeast sulfate-reducing system. 3. An intermediate in the reduction of 3'-phosphoryl-5'-adenosinephosphosulfate to sulfite.


Cell proliferation and morphological patterns in the hydroids Tubularia and Hydractinia.


Inositol biosynthesis in Neurospora crassa.


Isolation of trypanosomes of the T.brucei group from lion.


A survey of wild animals as potential reservoirs of trypanosomiasis in the Ulanga district (Tanzania).


AMP-activation of an allosteric NAD -dependent glutamate dehydrogenase.


The purification and properties of 6-phosphogluconate dehydrogenase from sheep liver.


Oxidized and reduced nicotinamide-adenine dinucleotide phosphate in tissue suspensions of rat liver. 1. The concentrations of NADP and NADPH(2) in homogenates of rat liver (expressed as mug./g. wet wt. of tissue homogenized) were compared with values obtained from intact samples of liver taken from the same female rat. With 0.25m-sucrose alone as the suspending medium, or in combination with tris buffer or 0.01-0.1m-nicotinamide, considerable decreases in the sum of the NADP+NADPH(2) concentrations were occasionally observed during 30min. storage of homogenates at 0 degrees . However, addition of 0.5m-nicotinamide+5mm-tris buffer to 0.25m-sucrose for use as a suspending medium maintained the sum of the NADP+NADPH(2) concentrations in homogenates at the level found in intact tissue for at least 30min. at 0 degrees . 2. The effects of freezing intact tissue and homogenates in liquid nitrogen before the extraction of NADP and NADPH(2) were studied. Freezing alone appears to convert a significant amount (approx. 30%) of liver NADPH(2) into an equivalent amount of NADP in intact tissue. This is discussed in terms of the ;bound NADP' reported by Burch, Lowry & Von Dippe (1963). 3. The intracellular distributions of NADP and NADPH(2) in intracellular fractions of rat liver were studied by using a modified centrifuging scheme that allows extraction of the isolated fractions to be performed within 45min. of killing the animal. Approx. 50% of the total NADP+NADPH(2) was found in the large-particle fractions and the remaining 50% was mostly in the soluble fraction of the cell. 4. Further investigations are reported on the nature of ;bound NADP' in rat liver. Most of this material appears associated with the ;nuclear' (containing nuclei, debris, erythrocytes etc.) or large-mitochondrial fractions, or both, obtained by low-speed centrifuging of rat-liver homogenates. 5. Although in some experiments the variations produced in the concentration of NADPH(2) present in large-particle fractions were followed by similar changes in that of ;bound NADP', in other cases no such direct relationship was obtained. Addition of phenazine methosulphate, for example, consistently lowered the concentration of NADPH(2) yet raised the concentration of ;bound NADP' in rat-liver mitochondrial fractions.


Digitonin incubation of spinach chloroplasts in tris (hydroxymethyl) methylglycine solutions of varying ionic strengths.


The influence of various factors upon testicular enzymes related to steroidogenesis.


Light-induced absorbance changes of two cytochrome b components in the electron-transport system of spinach chloroplasts.


Influence of solvents on the intramolecular energy transfer in NADH and NADPH.


Pyridine nucleotides in teleost islets.

Pyridine nucleotides in teleost islets.


Carotenoid fractionation in the plumose anemone Metridium.


A new pneumococcus type. Type 12A.

A new pneumococcus type. Type 12A.


Synthesis of the N-oxides of some drugs.


Spontaneous synaptic potentials and quantal release of transmitter in the stellate ganglion of the squid. 1. Several kinds of synapses have been studied in the stellate ganglion of the squid.2. A small electric coupling was found between giant fibres in different stellar nerves.3. Post-synaptic potentials recorded from the cells of small axons are composite, indicating that there are converging inputs from several pre-ganglionic fibres.4. Spontaneous miniature synaptic potentials were recorded from all types of synapses. Miniature potentials in the cells of small axons had a slower time course than those in the giant fibre system.5. Tetrodotoxin abolished nerve impulses in the ganglion but did not prevent the spontaneous quantal release of transmitter from the terminals, or its action on the post-synaptic membrane; nor did it prevent the increase in rate of release produced by depolarization of the presynaptic fibre.6. Glutamate depolarized the giant fibre when applied iontophoretically to the synaptic region. Similar doses applied intracellularly were without effect.


A study of synaptic transmission in the absence of nerve impulses. 1. The axo-axonic giant synapse in the stellate ganglion of the squid has been used to study synaptic transmission.2. When nerve impulses have been eliminated with tetrodotoxin, synaptic transfer of potential changes can still be obtained by applying brief depolarizing pulses to the presynaptic terminal.3. Suitably matched pulses are as effective as the normal presynaptic spike in evoking post-synaptic potentials. The synaptic delay and the time course of the post-synaptic potential are very similar to that in the normal preparation.4. The synaptic transfer (input/output) characteristic has been studied under different experimental conditions. With brief (1-2 msec) current pulses, post-synaptic response becomes detectable when the presynaptic depolarization exceeds about 30 mV. The post-synaptic potential increases about tenfold with 10 mV increments of presynaptic depolarization.5. Calcium increases, magnesium reduces the slope of the synaptic transfer curve. The influences on this curve of (i) duration of the pulse, (ii) preceding level of membrane potential, (iii) position of recording electrode, (iv) rate of repetitive stimulation are described.6. After loading the synaptic terminal with tetraethylammonium ions, large inside-positive potentials can be produced in the terminal and maintained for many milliseconds.7. By raising the internal potential to a sufficiently high level, synaptic transfer becomes suppressed during the pulse, and the post-synaptic response is delayed until the end of the pulse.8. This observation is in accord with a prediction of the ;calcium hypothesis', viz. that inward movement of a positively charged Ca compound, or of the calcium ion itself, constitutes one of the essential links in the ;electro-secretory' coupling process of the axon terminal.


Some pharmacological actions of 2-phenylquinoline methiodide.


Frequency-dependent potentiation by various drugs of the chronotropic response of isolated cat atria to sympathetic nerve stimulation.


Further observations on the pressor action of propranolol.


Diplococcus pneumoniae type 16 in laboratory rats. An acute respiratory disease in a colony of Wistar-derived rats is described. The infection, due to Diplococcus pneumoniae type 16, has apparently not been described previously in the rat. Rigid sanitary measures and treatment with penicillin were effective in controlling the disease.


The role of the adrenals in the rise of liver enzymes in tumor-bearing rats.


Prevention of 5-FU induced NADPH-D translocation in colonic epithelium by antibiotics and the effect on the intestinal bacterial flora.


Effect of oestradiol-17-beta and of L-thyroxine on activities of ovarian pyridine nucleotide dependent dehydrogenases in the lactating rat.


Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action.


Pacemaker-controlled hypotension in surgery.


Crystallization of the semiquinoid form of D-amino acid oxidase.


Effects of drugs on the mouse-killing (muricide) test and its relationship to amygdaloid function.


The differentiation of nematocysts and associated structures in the cnidaria.


Diagnosis and treatment of intrahepatic abscess.


Clinical diagnosis, evaluation and treatment of liver disease in in alcoholics.


In vivo and in vitro manifestations of adrenergic blockade in Bordetella pertussis-vaccinated mice. The in vivo metabolic events which follow the administration of epinephrine, norepinephrine, or isoproterenol were examined in normal, Bordetella pertussis-vaccinated, and alpha and beta adrenergically blocked mice. The normal hyperglycemic response to epinephrine was suppressed in all experimental groups. The pertussis-sensitized and beta-blocked animals produced similar split patterns of altered response not duplicated by the alpha-blocking compounds. Those catecholamines that normally increase free fatty acids and lactic acid in the circulation failed to do so in the pertussis-sensitized and beta-blocked animals; the inhibition of free fatty acid mobilization was also demonstrated with adipose tissue incubated in vitro. An extract of the pertussis organism added to incubation media prevented the catecholamine-induced free fatty acid response. The epinephrine-stabilizing effect of bovine serum albumin (Cohn-fraction V) was observed. The results of these studies further emphasize a correlation between pertussis-sensitized and beta-adrenergically blocked mice.


Brevity of the inductive phase in the immune response of mice to capsular polysaccharide antigens.


Flavensomycin, an inhibitor of enzyme reactions involving hydrogen transfer. The antifungal antibiotic flavensomycin inhibited the oxidation of amino acids and of glucose by Penicillium oxalicum. The compound inhibited l-amino acid oxidase (EC 1.4.3.2) activity for l-leucine and l-phenylalanine, and also d-amino acid oxidase (EC 1.4.3.3) in the oxidation for dl-alanine. The addition of flavin adenine dinucleotide, which is a cofactor for this enzyme, antagonized the action of the antibiotic. Glucose oxidase (EC 1.1.3.4) was also inhibited. The antibiotic inhibited the reduced nicotinamide adenine dinucleotide (NADH(2)) cytochrome c reductase (EC 1.6.2.1) as well as the much slower nonenzymatic reduction of this cytochrome by the nucleotide. Reduced cytochrome c was also oxidized nonenzymatically by flavensomycin. The antibiotic completely inhibited the action of rabbit muscle lactic dehydrogenase (EC 1.1.1.27) in promoting the reduction of pyruvate by NADH(2) but only slightly affected the reverse reaction. Alcohol dehydrogenase (EC 1.1.1.1) was also similarly inhibited. Flavensomycin prevented the reduction of nicotinamide adenine dinucleotide phosphate by isocitrate in the presence of isocitrate dehydrogenase (EC 1.1.1.42). The hexokinase (EC 2.7.1.1)-catalyzed phosphorylation of glucose, in which the adenosine triphosphate acts as a phosphate donor, was only slightly affected. Flavensomycin also inhibited the action of yeast lactate dehydrogenase (EC 1.1.2.3) on the reduction of cytochrome c. High concentrations of cytochrome c were antagonistic to this reaction. The results point to an interference with enzymatically controlled hydrogen or electron transfer as the mechanism of the antifungal activity of flavensomycin.


Daily rhythm in tyrosine concentration in human plasma: persistence on low-protein diets. The concentration of tyrosine in the plasma of normal males varies diurnally. It is lowest (9.5 +/- 0.35 micrograms per milliliter) between 0130 and 0230 hours and rises to a peak of 16.2 +/- 0.82 micrograms per milliliter by 1030 hours. This rhythm persists when subjects are maintained for 2 weeks on a diet that is very low in protein.


Pyruvate metabolism in Sarcina maxima.

Pyruvate metabolism in Sarcina maxima. The mechanisms of pyruvate cleavage and hydrogen production by Sarcina maxima were studied. It was found that a phosphoroclastic system for pyruvate oxidation, similar to that occurring in saccharolytic clostridia, is present in S. maxima. Cleavage of pyruvate by extracts of the latter organism resulted in the formation of acetyl phosphate, CO(2), and electrons which were transferred to ferredoxin. Formate was not an intermediate in this system. Pyruvate oxidation was coupled with ferredoxin-dependent nicotinamide adenine dinucleotide phosphate (NADP) reduction. A hydrogenase, active in particulate extracts of S. maxima, did not accept electrons from reduced ferredoxin. Formate was detected as a fermentation product when S. maxima was grown in media buffered with CaCO(3). Whole cells and extracts degraded formate to H(2) and CO(2). The evidence suggests that electrons generated by ferredoxin-linked pyruvate oxidation by S. maxima are not used for H(2) production, but that they serve for the reduction of NADP. Reduced NADP may be utilized by the organisms for synthesis of cell material. Production of H(2) by S. maxima may occur through a pyruvate clastic system similar to that present in coliform bacteria.


A rapid and sensitive method for the measurement of biological oxidation of an aromatic hydrocarbon catalyzed by liver microsomes.


Inhibition of Renilla reniformis bioluminescence by light: effects on luciferase and its substrates.


Hydroxymethylation of the benzene ring. II. Sequential formation of p-hydroxyaniline via hydroxymethylation of aniline by microsomes.


Pyridine nucleotides. 3. Response of dog thyroid pyridine nucleotides to hormonal control.


The possible role of conformational isomerism in the biological actions of acetylcholine.


Mechanism of the protective effect of reserpine on aggregated mice treated with (+)-amphetamine.


The tissue distribution and metabolism of amidopyrine in the rat and pregnant and non-pregnant rabbit.


Efficacy of haloperidol in drug refractory patients.


Antagonism of anti-inflammatory drugs on bradykinin-induced increase of capillary permeability.


The binding of salicylate to plasma proteins in different species.


Steric correlation between (--)-3-hydroxy-N-methylmorphinan and (--)-morphine and related compounds.


Release of [3H]noradrenaline from vasoconstrictor nerves.


Alpha-adrenergic blocking action of propranolol.


Evidence for dopamine receptor stimulation by apomorphine.


Effect of p-chlorophenylalanine on brain noradrenaline in mice.


Comparative investigation of the effect of cocaine and desipramine on bronchospasm in guinea-pigs.


Effects of glyceryl trinitrate on the aortic strip of rabbits.


Effect of adrenal demedullation and adrenalectomy on amphetamine toxicity in isolated and aggregated mice.


Bud morphogenesis in hydra.

Bud morphogenesis in hydra.


The effect of alpha- and beta-sympathotropic substances on spontaneous activity of the rabbit duodenum.


Influence of drugs on cardiac function and phosphorylase activity.


Study of the 11 beta-hydroxysteroid dehydrogenase in vitro. I. Biochemical characterization in spleen homogenate.


Pharmacologic influences on mating behavior in the male rat. Effects of d-amphetamine, LSD-25, strychnine, nicotine and various anticholinergic agents.


Preparation and fungicidal properties of some arylthioalkanoyl- and (arylsulphonyl)-aceto-hydroxamic acids.


A controlled evaluation of butaperazine in the neurotic anxiety syndrome.


Relieving symptoms of upper respiratory tract infection in entertainers.


Educational and personality characteristics of smokers and nonsmokers among university freshmen.


Biting times of nine species of New Guinea Culicidae (Diptera).


Arbovirus infections in Sarawak: further observations on mosquitoes.


Culiseta melanura (Coquillett) breeding in artificial containers.


Host-feeding patterns of Culex tarsalis in the Sacramento Valley, California, with notes on other species.


Reduced nicotinamide adenine dinucleotide oxidation in Escherichia coli particles. I. Properties and cleavage of the electron transport chain.


Reduced nicotinamide adenine dinucleotide oxidation in Escherichia coli particles. II. NADH dehydrogenases.


Interaction of mammary glucose 6-phosphate dehydrogenase with o-phenanthroline and its analogues.


Hypospadias.

Hypospadias.


The separation of DPN-linked and TPN-linked isocitrate dehydrogenase activities of mammalian liver.


Studies on chloral hydrate and camphor sensitivity in rats of different ages.


The effect of nicotinamide and homologs on the activity of inducible enzymes and NAD content of the rat liver.


On the pharmacology of alpha-methylated catecholamines and the mechanism of the antihypertensive action of alpha-methyldopa.


Identification of prostaglandin E2 as the principal vasodepressor lipid of rabbit renal medulla.


Conversion of androst-4-ene-3,17-dione-4-14-C to oestrogens by subcellular fractions of the human corpus luteum of the normal cycle.


Effect of AY-9944 on rat adrenal function.


Mast cells in adult rats on histamine-high and histamine-low diets, and on normal diet with and without anti-histamine.


Oxidative precipitation of hemoglobin H and its relation to reduced glutathione.


Effect of isolation in a constant environment on periodicity of physiological functions and performance levels.


The enzymatic conversion of sulfoxide to sulfone: the oxidation of methyl tetrahydrofurfuryl sulfoxide to the corresponding sulfone by rat liver microsomes.


Anesthetic considerations for renal transplant.


The adrenotropic receptors in the intestine (on the motor response of guinea pig ileum).


Cephalothin: antibacterial activity in vitro and treatment of infections in man.


Antagonism and synergism of six volatile anesthetic agents and flurothyl, a convulsant ether.


Role of deoxyribonuclease in genetic transformation. II. RNA as an inhibitor of doexyribonuclease activity in pneumococcal strains.


Role of deoxyribonuclease in genetic transformation. I. Deoxyribonuclease activity in variously transformable strains.


Respiratory-stimulating effect of doxapram hydrochloride in drug-induced respiratory depression.


Autonomic balance and reactivity in relation to indices of psychopathology on the MMPI.


Studies on mosquito attractants and stimulants. IV. AAn agent producing stimulative effects for oviposition of Culex pipiens fatigans in field water and the stimulative effects of various chemicals.


The metabolism of pronethalol.

The metabolism of pronethalol.


Cholinergic neurons in tunicates: an appraisal of the evidence.


Innervation of the lungs of the toad (Bufo marinus). I. Physiology and pharmacology.


Recent advances in experimental and molecular pathology. Atherosclerosis and metabolic disorder in the arterial wall.


Innervation of the lungs of the sleepy lizard (Trachysaurus rugosus). II. Physiology and pharmacology.


The role of a dicalcium phosphate chewing gum in the control of human dental caries.


Changes in amino acid concentrations associated with loss of spinal interneurons.


Field test of a sodium fluoride dentifrice containing acid orthophosphate and an insoluble metaphosphate abrasive--second year report.


Effect of unilateral cryptorchidism on sexual development in the pubescent male animal.


Hydrocortisone induction of tyrosine transaminase in regenerating rat liver.


The pouch technique in the surgical correction of cryptorchidism in infants and children.


Complications of vaccination.

Complications of vaccination.


Responses of the sino-atrial node to change in pressure in the sinus node artery.


Post-countershock arrhythmias in untreated and digitalized dogs.


Acute inflammation: a topographical and electron-microscope study of increased vascular permeability in bacterial and chemical pleurisy in the rat.


Mechanism for the reduction in pulmonary resistance induced by halothane.


Ganglion blockade by muscarine, oxotremorine and AHR-602.


How I treat atopic eczema in children.

How I treat atopic eczema in children.


Reversals in caries diagnosis.

Reversals in caries diagnosis.


Mental health and education conference. A report.


Studies with anaphylatoxin and DAS in milk.


Hypertension: current trends in diagnosis and treatment.


Analeptics: changing concepts, declining status.


Cryptorchidism in uniovular twins.

Cryptorchidism in uniovular twins.


Regulation of the "malic" enzyme in Neurospora crassa.


Experimental epilepsy and blood-brain barrier.


Cerebro-hepato-renal syndrome. A newly recognized hereditary disorder of multiple congenital defects, including sudanophilic leukodystrophy,  cirrhosis of the liver, and polycystic kidneys.


The relationship of hereditary hyperparathyroidism to endocrine adenomatosis.


The training of nonprofessional personnel in therapeutic interpersonal relationships.


Ocular manifestations of polyarteritis nodosa.


The value in caries prevention of methods for applying fluorides topically to the teeth.


The relation between the fluoridation of water and dental caries experience.


The value in caries prevention of other methods of increasing fluoride ingestion, apart from fluoridated water.


Autonomic nervous system and control of cardiac rhythm.


Blockade of catecholamine mediated release of free fatty acids from adipose tissue in vitro.


Hyperpolarization and blockade of ganglionic transmission.


Alteration of excitability of the rabbit ventricle by quinidine, disopyramide and pronethalol.


Investigation of the component reactions of oxidative sterol demethylation. Study of the aerobic and anaerobic processes.


Electron transport in relation to steroid biosynthesis. Inhibition of side-chain cleavage of cholesterol by hyperbaric oxygen.


The effect of convulsant drugs on coaxially stimulated guinea-pig ileum.


Studies of the female bladder in old age. IV. Drug effects in urinary incontinence.


Glucose-phosphorylating enzyme with high Km in human brain.


Possible dietary factors in the aetiology of chronic murine pneumonia, nephrosis and peri-arteritis.


A report on the side effects of Ambilhar (niridazole) and the effect of antihistamines and aspirin on these reactions.


Three-year study of mosquito-borne haemorrhagic fever in Calcutta.


Note to the laboratory tests with the sounds of mosquitoes.


Drug responses of three hospital population samples participating in a collaborative study.


TPNH-methemoglobin reductase deficiency: a new red-cell enzyme defect.


Pharmacogenetic factor in the convulsive responses of mice to flurothyl.


Similar effects of arginine-vasopressin and arginine-vasotocin on permeability of toad skin.


Effects of "diving" on cardiac output in ducks.


Pharmacological implications of microsomal enzyme induction.


Effect of ganglionic blocking on plasma renin activity in exercising and pain-stressed rats.


Glossary of chromosomal and genetic terms. II.


The effect of trypsin on regeneration inhibitors in tubularia.


Pruritus ani.

Pruritus ani.


Ladies' magazine reports physicians changing attitude toward 'the pill'.


Smoking and MMPI scores among entering freshmen.


Cardiovascular effects of pyrogallol and 4-tropoloneacetamide.


The influence of hemicholinium no. 3 (HC-3) on the response to vagal stimulation and acetylcholine content of rat atria.


Incorporation of 2-[14C]mevalonic acid into phytoene by isolated chloroplasts. 1. Chloroplasts prepared by the non-aqueous technique will, after fragmentation by ultrasonic treatment, incorporate [2-(14)C]mevalonic acid into phytoene, the first C(40) compound formed in the biosynthetic sequence to coloured carotenoids. 2. With suspensions containing 3.5mg. of chlorophyll, the optimum amounts of cofactor required were ATP (10mumoles), magnesium chloride (20mumoles) and glutathione (20mumoles); neither NAD(+) nor NADP(+) was required. 3. Very small amounts of squalene are also formed and synthesis is stimulated by addition of NADH or NADPH. Phytoene synthesis was not affected by the presence of these cofactors and no lycopersene (the C(40) homologue of squalene) was detected. 4. The phytol side chain of chlorophyll is also labelled under these conditions. 5. Preparations of developing chloroplasts are more active than preparations of mature chloroplasts.


Estimation of sample size for longitudinal clinical caries trials.


The arrestment of incipient dental caries in adults after the use of three different forms of SnF2 therapy: results after 30 months.


Combined use of a sodium fluoride prophylaxis paste and a spray containing acidulated sodium fluoride solution.


Blockade of the calorigenic, hyperglycemic, lactic acid-producing and fatty acid-mobilizing effects of adrenaline by an adrenergic beta-receptor blocking agent (pronethalol) in experiments on the rabbit.


GSR as a measure of the sexual component in hysteria.


On two infective filarial larvae in Mansonia crassipes with a note on other infective larvae in wild-caught mosquitoes in Ceylon.


Adaptatio of a filarial worm, Brugia patei, to a new mosquito host, Aedes togoi.


A comparison of oxyphencyclimine hydrochloride and propantheline bromide in patients with duodenal ulcer.


Production of gastric lesions in rats by combined cold and electrostress.


Chromatographic repair of storage-inactivated dihydrofolate reductase from Diplococcus pneumoniae.


This thing called problem solving.

This thing called problem solving.


The "walk-around" laboratory practical examination in evaluating clinical nursing skills.


The nurse: a thoughtful generalist-specialist.


Behavioral change through effective evaluation.


Lactic dehydrogenase and radiation-induced lymphoid leukaemia in mice.


The effect of the development of dieldrin resistance on the biotic potential of house flies in Liberia.


Illusions before the onset of unconsciousness in simulated flight.


Obsessional traits and emotional instability in a normal population.


Application of gas chromatography in manned space flight.


Relationship of personality to reaction under stress.


The action of the antihistaminic agents antazoline and meclizine on experimental arrhythmias.


On the mechanism of action of interferon on the early stage of vaccinia virus reproduction.


Plaque production by group A arboviruses. I. Influence of DEAE-dextran on plaques under agar and agarose. Plaque production under carboxymethylcellulose.


On the nature of the haemagglutinating factor in some strains of ECHO 7 and 12 viruses.


Relationship of clinical symptomatology to abnormal EEG findings: a family study.


The effect of carbon dioxide on the production of NADPH in the synthesis of fatty acids in normal and tumor cells.


Siet specificity and mechanism of human placental 17-beta-hydroxysteroid dehydrogenase.


In vitro cultivation of the insect trachea.


Parental bereavement in childhood. M.M.P.I. profiles in a depressed population.


Angiographic diagnosis of polyarteritis nodosa of the liver, kidney and mesentery.


Dehydrogenases during postembryonic development of Tribolium confusum Duval (Coleoptera). Malate dehydrogenase and malic enzyme in the particulate and soluble fractions.


The influence of chorionic gonadotrophin on the reduced NADP-DCPIP oxidoreductase system of rat testis.


The participation of kinins in the pathogenesis of early disturbances in the skin capillary permeability in local beta-ray irradiation.


Experimental model of congenital adrenal cortical hyperplasia produced in utero with an inhibitor of 11-beta-steroid hydroxylase.


Secondary antibody responses in haptenic systems: cell population selection by antigen.


Role of the phagocyte in host-parasite interactions. XI. Relationship between stimulated oxidative metabolism and hydrogen peroxide formation, and intracellular killing. The increased respiratory and hexose monophosphate activities noted in phagocytizing cells results in the formation of hydrogen peroxide. This is brought about by the oxidation of reduced nicotinamide adenine dinucleotide phosphate by its oxidase. Evidence is presented which indicates that this H(2)O(2) is involved in the intracellular killing of bacteria. When molecular oxygen was excluded from phagocytizing leukocytes by anaerobiosis, thus inhibiting H(2)O(2) formation, reduced intracellular killing was observed. In some cases the impairment of leukocytic bactericidal activity by anaerobiosis could be partially reversed by the addition of H(2)O(2). Exogenous catalase also could reduce intracellular killing. In addition, when leukocytic isolates were dialyzed so as to reduce endogenous H(2)O(2), the bactericidal activity of the leukocytes was significantly decreased under both aerobic and anaerobic conditions. These results occurred with both guinea pig and human leukocytes and with several test microorganisms.


Transseptal orchiopexy for cryptorchism.


Cross-reactions of the group-specific polysaccharides of streptococcal groups B and G in anti-pneumococcal sera with especial reference to type 23 and its determinants.


Polyarteritis nodosa involving the parotid gland. Report of a case.


A syndrome of benign congenital hypotonia, gross obesity, delayed intellectual development, retarded bone age, and unusual facies.


Urban epidemic encephalitis in Houston caused by a group B arbovirus (SLE).


Report on the 8th International Conference of the International Planned Parenthood Federation.


Rural epidemic encephalitis in Venezuela caused by a group A arbovirus (VEE).


Treatment of actinic dermatoses and vitiligo.


Smale: NSF's records do not support the charges.


Study of the virulence of tick-borne encephalitis virus. 8. Differentiation by chromatography on hydroxylapatite of clones possessing distinct biological properties.


The IgG and IgM antiviral antibody response during polyoma infection and oncogenesis.


An enzymic method for measurement of glycogen.


Binding of chlorpromazine and thioproperazine in vitro. I. Results of centrifugation methods with tissue and mitochondria from rat liver and human leukocytes.


Reduction of in vitro autohemolysis in hereditary sperocytosis by impermeant molecules.


A coupling factor of oxidative phosphorylation without adenosine triphosphatase activity from beef heart mitochondria.


The potentiation of neuromuscular blocking agents by quinidine.


Manned submersibles for research. These immature but developing tools open another door for examining history and current processes. The past decade has seen the development of small submersibles as a new and effective tool of geology, acoustics, marine biology, and physical oceanography. As with all tools, it has special capabilities and limitations. The methods of use and the needed engineering improvements are being identified. Scientists, engineers, government, and industry are responding so that advances toward both less-expensive simple vehicles and high-performance complex vehicles are proceeding.


The interactions of neuromuscular blocking agents in man: the role of hexafluorenium.


Nodamura virus from Japan: a new and unusual arbovirus resistant to diethyl ether and chloroform.


Laboratory studies on transmission of Chikungunya virus by mosquitoes.


Statistical versus clinical prediction: length of neuropsychiatric hospital stay.


Löffler's pneumonia terminating in fatal periarteritis nodosa.


Wringer injuries.

Wringer injuries.


Physiological effects of space cabin atmospheres.


Pentobarbital anesthesia in labor.

Pentobarbital anesthesia in labor.


Evaluation of a new convulsant for anticonvulsant screening.


The influence of cobalt on canine adrenocortical function.


The capsular polysaccharide of type I Pneumococcus. I. Purification and chemical modification.


Studies of the female bladder in old age. IV. Drug effects in urinary incontinence.


Evaluation of potential antirheumatic drugs in vitro using lymphocytes and epithelial cells. The selective action of indoxole, methyl glyoxal and chloroquine.


The fate of [14C] thalidomide in the pregnant hamster.


Influence of the route of administration on the toxicity of some cholinesterase inhibitors.


Excitation of Mytilus smooth muscle.

Excitation of Mytilus smooth muscle. 1. Membrane potentials and tension were recorded during nerve stimulation and direct stimulation of smooth muscle cells of the anterior byssus retractor muscle of Mytilus edulis L.2. The resting potential averaged 65 mV (range 55-72 mV).3. Junction potentials reached 25 mV and decayed to one half maximum amplitude in 500 msec. Spatial summation and facilitation of junction potentials were observed.4. Action potentials, 50 msec in duration and up to 50 mV in amplitude were fired at a membrane potential of 35-40 mV. No overshoot was observed.5. Contraction in response to neural stimulation was associated with spike discharge. Measurement of tension and depolarization in muscle bundles at high K(+) indicated that tension is only produced at membrane potentials similar to those achieved by spike discharge.6. Blocking of junction potentials, spike discharge and contraction by methantheline, an acetylcholine antagonist, supports the hypothesis that the muscle is excited by cholinergic nerves. However, evidence of a presynaptic action of methantheline complicates this argument.


3beta-hydroxy-C27-steroid dehydrogenases in mouse liver microsomes.


Hypospadias. A modification of the Denis Browne method.


5-hydroxytryptamine participation in the vagal inhibitory innervation of the stomach. 1. Intraluminal pressure was recorded from the isolated guinea-pig and mouse stomach with the vagus and sympathetic nerves attached.2. The response to vagal stimulation, which consists of an excitatory and an inhibitory component, resembled the response to 5-hydroxytryptamine (5-HT), which has no direct action on the muscle but acts on intrinsic excitatory and inhibitory ganglia.3. In the presence of hyoscine, the effect of vagal stimulation, of nicotinic compounds and of 5-HT were all purely relaxant. Competitive block of ganglionic receptors for acetylcholine reduced the vagal relaxation without antagonizing 5-HT. Specific desensitization of ganglionic receptors for 5-HT reduced the vagal relaxation without antagonizing nicotinic compounds.4. During the early phase of the blocking action of nicotine, responses to vagal stimulation and to 5-HT were both abolished. As the non-specific antagonism changed to the later phase of specific antagonism to acetylcholine, the inhibitory (but not the excitatory) component of the vagal response recovered partially, in parallel with the recovery of the relaxant effect of 5-HT.5. The vagal inhibitory effect was completely abolished only when competitive block of acetylcholine receptors was combined with desensitization of 5-HT receptors.6. Stimulation of the mouse stomach (after asphyxiation of the mucosa and exclusion of the luminal content) in the presence of hyoscine caused the release of 5-HT; this release was blocked by tetrodotoxin.7. The results, together with previous observations that 5-HT is contained within preganglionic nerve fibres in the myenteric plexus, are consistent with the hypothesis that 5-HT, with acetylcholine, may be a neurotransmitter in the vagal inhibitory innervation of the stomach.


The effects of personality type on drug response.


Effect of alcohol on glucose production and lactate, pyruvate and ketone body metabolism by the isolated perfused rat liver.


Reduced nicotinamide dinucleotide phosphate diaphorase from Bacillus subtilis.


Ovarian control of certain enzymes in the mammary gland of the lactating rat.


Mental state, cognitive functioning, physical health, and social class in the community aged.


Oral health conditions of school children on two solitary islands of Okinawa.


Public knowledge of ipecac syrup in the management of accidental poisonings.


Detailing ipecac. Report of the Committee on Poison Control, Rocky Mountain Pediatric Society.


The measurement of alcoholic response to treatment by Barron's Ego-strength Scale.


The significance of terminal phalangeal osteosclerosis.


Bacterial flora in chronic, purulent maxillary sinusitis.


Enteric-coated potassium chloride tablets and ulcer of the small intestine.


Summary of the International Symposium on the Epidemiology of Tumors. June, 1965.


A review of research with measures of ego strength derived from the MMPI and the Rorschach.


The effects of stress on self-attribution of hostility among ego control patterns.


Pharmacology of animal venoms.

Pharmacology of animal venoms.


Structure and function of D-amino acid oxidase. I. Further purification of hog kidney D-amino acid oxidase and its hydrodynamic and optical rotatory properties.


Studies on pattern regulation in Hydra. IV. The effect of colcemide and puromycin on polarity and regulation.


Structure and function of D-amino acid oxidase. II. Terminal structure and amino acid composition of hog kidney D-amino acid oxidase.


Personality variables and allergic skin reactivity. A cross-validation study.


Selective loss of responsiveness to alpha adrenergic receptor stimulation after cold storage of the rabbit intestine.


Studies in autoerythrocyte sensitization. The induction of purpuric lesions by hypnotic suggestion.


Species variation and the antihistaminic properties of 3,4-dimethoxyphenethylamine.


Determination of phenobarbital and phenytoin in serum by ultraviolet spectrophotometry.


Histochemical demonstration of some DPN and TPN-linked dehydrogenases in Trichomonas vaginalis.


The effects of hemicholinium (HC-3) and some anticholinesterases on the vascular responses to sympathetic nerve stimulation.


The effects of repeated flurothyl-induced seizures on convulsive thresholds and brain monoamines in rats.


Regulation of the activity of glucose-6-phosphate dehydrogenase by NADP+ and NADPH.


A single glyceraldehyde-3-phosphate dehydrogenase active with NAD and NADP in Anabaena variabilis.


Mechanism of enzyme action. II. Characterization of the purple intermediate in the anaerobic reaction of D-amino-acid oxidase with D-alanine.


A place for the Cheatle-Henry approach in pediatric surgery?


Myocardial infarction.

Myocardial infarction.


Suppression by actidione of development of rat liver L-tyrosine: 2-oxoglutarate aminotransferase activity.


Immunopathological mechanisms and their treatment.


Hematomas of the small bowel--three etiologies.


Empyema in pediatric patients in Iran.

Empyema in pediatric patients in Iran.


Implementation of a family planning program by a public health agency.


Salmonella infections in domestic animals.


Hospitals, chaplains and medical personnel.


The Oakfield project in dental health education.


Malaria in Queensland, 1964 to 1966.

Malaria in Queensland, 1964 to 1966.


Long term storage of Diplococcus pneumoniae.


Enzyme levels in rats adapted to 36-hour fasting.


A preliminary evaluation of magnesium pemoline in chronic schizophrenic patients.


Regulation of fatty acid synthesis in adipose tissue.