The fine structure of the ventricular muscle cells of the soft-shelled turtle heart (Amyda), with special reference to the sarcoplasmic reticulum.


Hepatic hemangioma: successful resection in a neonate.


Ultrastructural studies of a malignant fibrous mesothelioma of the pleura.


More common radionuclide examinations in children: indications for use with a discussion of radiation dose received.


Experimental gestational mumps virus infection and endocardial fibroelastosis.


The spiral pattern during development.

The spiral pattern during development.


Fibrinolytic activity of normal human tunica vaginalis and tunica vaginalis of hydroceles.


An ultrastructural and radioautographic study of neocortical ontogeny.


Corynebacterium pyogenes keratitis in a newborn calf.


Cross-reactive antigens of bovine streptococci.


Nutritional hypercalcitoninism in bulls.


The effect of replenishment of iron stores after phlebotomy therapy in porphyria cutanea tarda.


Radiography in equine carpal lameness.

Radiography in equine carpal lameness.


The experimental production of mastitis in sheep by Mycobacterium smegmatis and Mycobacterium fortuitum.


Lesions in neonatal lambs resulting from maternal ingestion of locoweed.


Penicillinemia and penicillinlactia in the bovine following intramuscular administration of benzyl penicillin combinations.


Congenital lateral luxation of the patella in the horse.


Anthelmintic activity of L-tetramisole against experimental Metastronglylus SPP. infection in swine.


Atrophic rhinitis produced by intranasal inoculation of Bordetella bronchiseptica in hysterectomy produced colostrum-deprived pigs.


Clinical pathological conference.

Clinical pathological conference.


Multiple fibroblastic tumor in a 2-month-old calf.


The effect of host immunity on the metabolism of Nippostrongylus brasiliensis.


Milk ejection in the rat: recordings of intramammary pressure during suckling.


Binding and breakdown of ( 3 H) oxytocin in rat mammary tissue in vitro.


Hormonal modication of aggressive behavior between female goldne hamsters.


Changes in insulin, glucocorticoids, glucose and ketone body levels in blood of cows with a thyroxine-induced ketosis.


Effect of prolactin on nucleic acid metabolism during lactogenesis in the rabbit.


Sex-attractant properties of ether extracts of vaginal secretions from rhesus monkeys.


Problems in electrical stimulation of afferent pathways for oxytocin release.


The effects of prolactin on fatty acid synthesis by rabbit mammary gland in vitro.


Analysis of milk secreted sponatenously by virgin rats bearing induced mammary tumours.


The action of clomiphene in the ferret.

The action of clomiphene in the ferret.


Inhibitory action of MER-25 on adnrogen-induced oestrous behaviour in the ovariectomized rabbit.


Internal feedback of luteinizing hormone in cyclic female rats.


Plasma prolactin in the oestrous cycle of the ewe: effect of pituitary stalk section.


Post-coital unilateral ovariectomy and ipsilateral survival of the conceptus.


Zinc and testosterone uptake by the prostrate in vitro.


Sexual attractants in rodent urine.

Sexual attractants in rodent urine.


The effect of sex hormones on plasma insulin and glucose tolerance in the female rat.


Oestrogen synthesis by rat ovaries in vitro. Effects of enodgenous and exogenous gonadotrophins.


Urinary oestrogen levels in the Beagle bitch.


Luteal volume changes, luteal acid phosphatase activity and ovarian oestradiol secretion in the hypophysectomized pregnant rat.


Apparent movement and real movement detection in the pigeon: stimulus generalization. Pigeons were trained to discriminate apparent movement and real movement in visual displays showing horizontal movement. Generalization testing on the dimension of directional movement yielded gradients that sloped as movement changed from horizontal to vertical. Evidence of generalization between apparent movement and real movement was found in equivalent response rates to training displays of either type. Extremely low response rates to training displays pulsating but showing no movement eliminated flicker as the basis of the discrimination.


Nerve endings in the heart of amphibia.

Nerve endings in the heart of amphibia.


LSD-accentuated individual type of social behavior in mice.


Impulses in response to the light stimulus from the ciliary nerves of the chick: preliminary report.


Utilization of substrates for energy production by the growing brain.


The effects of intrauterine malnutrition upon later development in humans.


Undernutrition and the developing brain: the use of animal models ot elucidate the human problem.


Maintenance of the corpus luteum in hysterectomized mares.


Biochemistry and psychiatry.

Biochemistry and psychiatry.


Developmental polymorphism in bovine hemoglobin.


Accumulation of uterine luminal fluid after uterine ligation in guinea pigs.


Effects of fluoride, calcium, and phosphorus on porcine bone.


Electroencephalograms of anesthetized dogs with hydrocephalus.


A method for combined light and electron microscopic study of individual cells: application to antibody-forming cells.


A modified fluorometric micromethod for DNA.


Isolation and cytological properties of biochemically marked L-cell line.


Milk yield and its influence on 205-day weight of beef calves.


Respiration of mitochondria isolated from dark-cutting beef.


Comparative utilization of casein, fish protein concentrate and isolated soybean protein in liquid diets for growth of baby pigs.


Control of estrus and ovulation using subcutaneous implants and estrogens in beef cattle.


Effect of cis and trans isomers of clomiphene on reproductive performance in ewes.


Influence of ovarian hormones on blood serum fatty acids.


Influence of energy level, creep feeding and lactation stage on ewe milk and lamb growth characters.


Termination of pregnancy in mink by repeated injections during the period preceding implantation. When given a series of 5 sequential daily injections of luteinizing hormone or salene, pregnancies were terminated in 13 of 14 animals.  The same effect was not observed in animals injected singly.  The observed results may be interpreted as a response to the stress of handling and treatment.


Supplementation for wintering range ewe lambs: effect on growth and estrus as ewe lambs.


Toxicological studies on cutworms. 8. Toxicity of three insecticides to the various stages in the development of the darksided cutworm.


Effects of certain systemic insecticides on growth and yield of soybeans.


Tolerance of the stages of Stetborus punctum to selected insecticided and miticides.


Dithiocarbamate fungicides for control of pear Psylla.


Large volume urography in the cat.

Large volume urography in the cat.


Angioblastic meningioma with hepatic metastasis. Infrequently, intracranial neoplasms metastasize to extracranial sites. In 1963, Glasauer and Yuan reviewed the 88 reported cases of metastatic intracranial tumours of which approximately two-fifths were meningiomas. This report concerns an angioblastic meningioma with a large hepatic metastasis. Cushing's original classification of angioblastic meningiomas and the differential diagnosis between these tumours and the haemangiopericytoma and cerebellar haemangioblastoma are discussed.


Drug interactions: effect of methylphenidate on the disposition of diphenylhydantoin in man.


Medium-chain triglycerides as a therapy for intractable childhood epilepsy.


Sensitivity studies of L-dopa metabolites in reserpinized rats and their clinical significance.


Seven cases of cerebromedullospinal disconnection: the "locked-in" syndrome.


Sterol test for human brain tumors: relationship with different oncotypes.


Positional nystagmus: an early sign in medulloblastoma.


Hypokalemic myopathy in chronic alcoholism.


A lethal glossopharyngeal defect in the dog.


Multiple sclerosis in the child of conjugal multiple sclerosis patients.


A study of salt-soluble proteins of poultry meat by chromatography.


Effect of melengestrol acetate on the bovine ovary.


Microheterogeneity of horse spleen ferritin and apoferritin.


Influence of pH and electrolyte on the fluorescence of bovine serum albumin.


Nature of the alteration of the fluorescence spectrum of bovine serum albumin produced by the binding of dodecyl sulfate.


Luminescence of ribonuclease A.

Luminescence of ribonuclease A.


Molecular basis for multiplicity of Pacific salmon hemoglobins: evidence for in vivo existence of molecular species with up to four different polypeptides.


Copper in edible oils: trace amounts determined by atomic absorption spectroscopy.


Soy flour and grits for use in food products.


Effects of volume and distribution of milk on the oxytocin-induced contraction of the lactating rat mammary gland in vivo.


Stimulation of rabbit ovaries by human chorionic gonadotrophin in the absence of endogenous gonadotrophins.


Fertility and mating behaviour of androgenized mice.


The effect of prostaglandins on the guinea-pig mammary gland.


Microbial transformation of antibiotics: phosphorylation of clindamycin by Streptomyces coelicolor Müller. Addition of clindamycin to whole-cell cultures of Streptomyces coelicolor Müller resulted in the loss of in vitro activity against organisms sensitive to clindamycin. Incubation of such culture filtrates with alkaline phosphatase generated a biologically active material identified as clindamycin. Fermentation broths containing inactivated clindamycin yielded clindamycin 3-phosphate, the structure of which was established by physical-chemical and enzymatic studies. Clindamycin was phosphorylated by lysates and partially purified enzyme preparations from S. coelicolor Müller. These reactions require a ribonucleoside triphosphate and Mg(2+). The product of the cell-free reactions was identified as clindamycin 3-phosphate.


Uptake of tritiated oxytocin into the neurohypophysis of the rat.


Freud's Gradiva: mater nuda rediviva. A wish-fulfilment of the 'memory' on the Acropolis.


Ectopic production of prolactin.

Ectopic production of prolactin.


A comparative study of the interactions of the nonpolar fluorescent ligand, 1-anilino-8-naphthalene sulfonic acid, with butyryl and acetylcholinesterase.


Fluorescence polarization characteristics of the complexes between ethidium bromide and rRNA, tRNA, and DNA.


Membrane glycoprotein transferases: time courses of activity changes in a synchronized cell population and enzyme activity half-lives in an asynchronous population.


One-electron reactions in biochemical systems as studied by pulse radiolysis. V. Cytochrome c.


Lysis of viable yeast cells by enzymes of Arthrobacter luteus.


Solubilization of a reticulocyte ribosomal fraction responsible for the decline in ribosomal activity with cell maturation.


Lead poisoning in horses. An environmental health hazard.


Biosynthesis of glycosphingolipids by mouse neuroblastoma (NB41A), rat glia (RGC-6) and human glia (CHB-4) in cell culture.


On the different positional specificities of peroxidation of linoleate shown by two isozymes of soybean lipoxygenase.


Measurement of antibody-producing capacity to flagellin in man. IV. Studies in autoimmune disease, allergy and after azathioprine treatment.


General aspects of erythrocyte physiology and biochemistry.


Inhibition of sugar transport by cystic fibrosis plasma.


Exchange-transfusion by means of microinfusion rolling pump.


Effects of cycloheximide on the accumulation of tobacco rattle virus in leaf discs of Nicotiana clevelandii.


Studies with avian influenza A viruses: serological relations of the haemagglutinin and neuraminidase antigens of ten virus isolates.


Mechanism of carcinogenesis by RNA tumour viruses: the RNA-and DNA-dependent DNA polymerase activities of feline sarcoma virus.


Histopathology of tumors of canine alimentary tract produced by N-methyl-N'-nitro-N-nitrosoguanidine, with particular reference to gastric carcinomas.


Intracerebral lesions causing stereotyped behaviour in rats.


The effect of zinc on calves with hereditary thymus hypoplasia (lethal trait A 46).


Deoxyribonucleoside triphosphate pools in synchronized and drug-inhibited L 929  cells.


Transfer RNA methylases during sea urchin embryogenesis.


Anti-inosine antibodies.

Anti-inosine antibodies.


Stability of free ribosomes, derived ribosomes and polysomes of the sea urchin.


The distribution of phosphoarginine and phosphocreatine in marine invertebrates.


Histoenzymorphology of frog oviducal  -glucuronidase in seasonal breeding-hibernation cycle: a histochemical model for hormone-enzyme relation.


Dissociation of ribosomes induced by centrifugation: evidence for doubting conformational changes in ribosomes.


Magnetically coupled micromanipulator for use within a sealed chamber.


Changes in activities of zinc-dependent enzymes in zinc-deficient tissues of rats.


Acanthocheilonema dracunculoides (Cobbold, 1870) in dogs in Lahore, West Pakistan.


Observations on the resistance to schistosome infection of neonatal mice born to immune mothers with a demonstration of increased resistance in lactating mice.


An Editorial.

An Editorial.


Studies of guinea-worm (Dracunculus medinensis). Intra-uterine development of the larvae.


Radio-immuno assay of lactoferrin in blood plasma of breast cancer patients, lactating and normal women; prevention of false high levels caused by leakage from neutrophile leucocytes in vitro.


Effect of protein quality on liver xanthine dehydrogenase and kidney arginase activities in chicks.


The effect of mescaline and bufotenine on some central actions of noradrenaline.


A language pattern co-occurring with violence-permissiveness.


Chromosome aberrations in oogenesis and embryogenesis of mammals and man.


Proteins of normal hair and of cystine-deficient hair from mentally retarded siblings. 1. S-Carboxymethylkerateines extracted from normal hair can be fractionated into high-sulphur and low-sulphur proteins similar to those obtained from sheep's wool. Normal human hair gives a major high-sulphur protein of higher molecular weight and S-carboxymethylcysteine content than any isolated from normal sheep's wool. 2. The proteins from cystine-deficient hair can also be divided into high-sulphur and low-sulphur proteins. There is a lower proportion of high-sulphur protein in cystine-deficient hair than in normal hair. 3. The high-sulphur proteins from cystine-deficient hair have an abnormal amino acid composition and in particular are lower in S-carboxymethylcysteine content than the corresponding proteins from normal hair. New components are present and the content of very high-sulphur proteins of high molecular weight is much decreased. The low-sulphur proteins of cystine-deficient hair are probably also deficient in S-carboxymethylcysteine. 4. The proteins of cystine-deficient hair probably resemble those in the normal hair root, except that disulphide-bridge formation has occurred.


The disulphide bonds of erabutoxin a, a neurotoxic protein of a sea-snake (Laticauda semifasciata) venom. Erabutoxin a was partially hydrolysed with enzymes and sulphuric acid and the resulting peptides were separated from each other by column chromatography and paper electrophoresis. From the results of amino acid analyses of the sulphur-containing peptides and their oxidized components, all four disulphide bridges in the toxin molecule were located. The disulphide bonds were found between half-cystine residues at positions 3 and 24, 17 and 41, 43 and 54, and 55 and 60 from the N-terminus.


Unsuitability of indoxyl acetate as a substrate for the assay of testicular hyaluronidase. The most recently published method for the assay of testicular hyaluronidase preparations was based on the premise that the enzyme also exhibited carboxylesterase activity towards indoxyl acetate. Studies on the relative enzyme activities of various hyaluronidase preparations towards hyaluronate and indoxyl acetate, the relative stabilities towards pH, temperature and mechanical shaking and the behaviour towards a variety of inhibitors, showed that the activities towards the two substrates reflected the presence of at least two different enzyme systems in the preparations. Gel chromatography and polyacrylamide-gel-electrophoresis experiments confirmed these conclusions and the collective findings clearly establish that methods based on the use of indoxyl acetate cannot be employed to measure testicular hyaluronidase activity.


Studies on the accessibility of deoxyribonucleic acid in deoxyribonucleoprotein to cationic molecules. The binding of deoxyribonucleoprotein to Toluidine Blue, to cetylpyridinium chloride and to polylysine of various molecular weights was studied to determine the percentage of free DNA phosphate groups in deoxyribonucleoprotein. Binding was measured by addition of these reagents to deoxyribonucleoprotein at a range of concentrations such that complete precipitation of the deoxyribonucleoprotein occurred. With Toluidine Blue the binding corresponded to about 48% of the DNA phosphates in deoxyribonucleoprotein. The dye did not cause appreciable displacement of protein from the DNA. With cetylpyridinium chloride the binding corresponded to about 41% of the DNA phosphates. With polylysine preparations of molecular weight 1250 and 7790 the binding values for deoxyribonucleoprotein were 46 and 38% respectively. The results suggest that the free phosphates lie in stretches sufficiently long to accommodate most of each polylysine molecule. With polylysine of molecular weight 62000 cross-linking of free stretches of DNA on different deoxyribonucleoprotein molecules probably occurs. It is concluded that although most of the free phosphates are probably ;hidden' beneath covering histone, corresponding perhaps to runs of non-basic residues in the latter, they are surprisingly accessible to very large molecules. The relevance of this finding to the problem of gene repression is discussed.


Nutritive value of the winged bean (Psophocarpus palustris Desv.).


Failure of leucine, arginine, and epinephrine to alter plasma insulin levels in vitro.


A rapid radioimmunoassay of human chorionic somatomammotropin (HCS or HPL) using dioxan.


Standardization trial of the antiglobulin (Coombs) test applied in the serological diagnosis of brucellosis in cattle.


Mast cells in nasal polyps.

Mast cells in nasal polyps.


Protein value of Colombian opaque-2 corn for young adult men.


The hypothalamic neurosecretory pathways for the release of oxytocin and vasopressin in the cat. 1. The neurones of the supraoptic nucleus (SON) and paraventricular nucleus (PVN) were stimulated electrically in lactating cats under chloralose anaesthesia. Milk-ejection responses were used to monitor the release of oxytocin and vasopressin and both hormones were assayed in samples of blood collected during stimulation. The position of the tip of the stimulating electrode was confirmed from brain sections stained selectively for cystine-rich neurosecretory material.2. A previous finding that stimulation of the SON in the cat releases vasopressin without oxytocin was confirmed.3. Stimulation of the PVN caused both hormones to be released. The ratio of their concentrations in blood was variable; this suggests release from separate neurones.4. Both hormones were also released on stimulation of the median eminence but not of the zone lying vertically between this structure and the PVN. No neurosecretory material was detected in this zone. These findings argue against the existence of a direct or medial paraventriculo-hypophysial pathway running downwards along the wall of the third ventricle.5. Study of sections from unstimulated brains confirmed that the tractus paraventricularis cinereus of Greving which runs ventro-laterally from the PVN towards the SON, represents the principal efferent pathway for neurosecretory fibres from the PVN.6. The results are discussed in relation to the problem of the independent release of oxytocin and vasopressin in response to physiological stimulation of the neurohypophysis.


Hypermagnesemia in malignant neoplasms.

Hypermagnesemia in malignant neoplasms.


Diffuse leiomyomatosis of the lungs (Leiomyomatosis diffusa pulmonum).


Role of dominance status in shock-stimulated agonistic behavior.


Acquisition of conditioned avoidance response in rats under the influence of addicting drugs.


Preliminary studies on the toxicity of black widow spider eggs.


Comparison of the effects of atelopidtoxin with those of tetrodotoxin, saxitoxin and batrachotoxin on beating of cultured chick heart cells.


Temperature-sensitive mutants of reovirus type 3 features of genetic recombination.


Potato spindle tuber viroid. V. Failure of immunological tests to disclose double-stranded RNA or RNA-DNA hybrids.


Isolation of influenza virus ribonucleoprotein from infected cells. Demonstration of the presence of negative-stranded RNA in viral RNP.


Feminine psychology revisited, circa 1970.


Mechanisms involved in nongenetic reactivation of frog polyhedral cytoplasmic deoxyribovirus: evidence for an RNA polymerase in the virion.


Early deaths.

Early deaths.


Hamster-hair hypersensitivity in adults of low atopic status.


Misuse of Drugs Act 1971.

Misuse of Drugs Act 1971.


Breast-milk jaundice and oral contraceptives. Among breast-fed infants in the normal lying-in wards of a maternity hospital a significantly higher incidence of "idiopathic" jaundice was found in infants of mothers who had been receiving the contraceptive pill before the present pregnancy than in the infants whose mothers never had the pill. The pill became widely used in society at about the same time as breast-milk jaundice was first reported.


The relationship between the chemical structure of aflatoxins and their effect on bovine pancreas deoxyribonuclease.


Porphyrin biosynthesis in soybean callus tissue system. 8. Isolation, purification and general properties of succinyl CoA synthetase.


Effect of sub-optimal temperatures on survival of mammalian cells.


Bipolar and tetrapolar cleavage time in sea urchin eggs.


Histone methylkinase levels in synchronized mammalian cells.


A replica plating method of cultured mammalian cells for somatic cell genetics.


DNA-dependent RNA synthesis in fixed cells during spermatogenesis in mouse.


Mutagenesis to aminopterin resistance in cultured hamster cells.


Protein renewal in anti-peroxidase antibody forming cells. II. Combination of ultrastructural immuno-cytochemistry and autoradiography in "pulse-chase" experiments.


Permeability coefficients of bull spermatozoa for water and polyhydric alcohols.


Are chromosome secondary constrictions nucleolar organizers? A re-examination using a laser microbeam.


Tissue specificity of non-histone chromosomal proteins.


Mitomycin C treated cells as feeders.

Mitomycin C treated cells as feeders.


Tritiated thymidine uptake by mouse bone marrow cells in liquid culture.


Quinacrine fluorescent patterns of the chromosomes in cell lines of the rat-kangaroo (Potorous tridactylus apicalis).


The effect of castration and ovarian implantation on aggressive behaviour of male hamsters.


Differential sensitivity of human normal and malignant cells to 8-azahypoxanthine in vitro.


Induction of lactation in the guinea-pig.


Plasma oestrogen levels during the canine oestrous cycle.


Studies on aging in a bdelloid rotifer. II. The effects of various environmental conditions and maternal age on longevity and fecundity.


Antepartum haemorrhage of uncertain origin.


Effects of feeding of improved rice diet on rats.


Cellular immunity as a host response to squamous carcinoma of the cervix.


The effect of oral contraceptives on folate metabolism.


Diabetes in pregnancy.

Diabetes in pregnancy.


Comparative actions of selected vasoactive drugs on isolated human uterine arteries.


Study of the effects of gamma-radiation on eggs and miracidia of Schistosoma mansoni.


The induction of abortion by prostaglandin F 2  . PGF2alpha was administered intravenously to 15 women for induction of therapeutic abortion, missed abortion, or prematurely ruptured membranes.  7 women in the 6th to the 14th weeks of pregnancy were infused with 41 to 55 mcg/minute of PGF2alpha.  Uterine response appeared after 10-20 minutes, and contractions became regular after 120-200 minutes.  Infusion time ranged from 6 hours 16 minutes-10 hours 36 minutes.  In 3 cases there was complete expulsion of fetus and placenta.  Diarrhea was seen in all patients; nausea and vomiting appeared in some cases.  8 patients in the 18-29th weeks of gestation were treated with intravenous infusion of 11-33 mcg/min.  This small dose cause remarkable contractions, and abortion was successful in all 4 cases of missed abortion, 3 cases of premature rupture of membranes, and 1 case of therapeutic abortion.  Blood loss was minimal and there were few side effects.  This study shows that intravenous infusion of PGF2alpha for the induction of midtrimester abortion is a safe and more reliable method than hypertonic saline or glucose solution.  Vacuum aspiration remains the preferred method for induced abortion in the 1st trimester of pregnancy.


The interaction between succinylcholine and subparalyzing doses of d-tubocurarine and gallamine in man.


Influence of plasma lipids on the activity of lipoprotein lipase.


The effect of oestrogen on the prostatic metabolism of testosterone in tissue culture.


Is synthesis of glucose 6-phosphate dehydrogenase induced by a metabolite of glucose?


A catalytic mechanism for pig plasma benzylamine oxidase.


Changes in drug-metabolizing activities in the livers of suckling rats as a result of treatment of the lactating mothers with phenobarbitone and chlorpromazine. 1. Lactating female rats were treated with phenobarbitone or chlorpromazine. 2. Hepatic microsomal fractions from the suckling offspring were studied to see if changes had occurred in the rates of drug metabolism. 3. Treatment with phenobarbitone significantly increased the cytochrome P-450 concentration, the activity of NADPH-cytochrome c reductase (EC 1.6.2.3) and the rates of metabolism of aniline, ethylmorphine and [2-(14)C]pentobarbitone. 4. Treatment with chlorpromazine produced only small increases in the cytochrome P-450 concentration and the rate of hydroxylation of aniline.


Blood-pressure changes in raised intracranial pressure.


Influence of age, stage of disease, and menstrual status on urinary steroids in women with early breast cancer.


Observations on whether immunodepression is associated with the presence of a tumour in mice.


Studies on fibrinolysis during experimental and clinical liver perfusion in the pig.


Concentrations of oestrogen and progesterone in the plasma of non-pregnant, pregnant and lactating guinea-pigs.


Lysosomes as mediators of parenchymal lesions in adjuvant-induced arthritis in rats.


Fine-structural changes of reacting glial cells by experimental brain tumours induced transplacentally by N-ethyl-N-nitrosourea in rats.


Muscle cell death in developing human skeletal muscle.


Studies on the endocrine control of the rat foetal thymus.


The secrectory proteins of the sol phase sputum.


The influence of male proximity and dietary restriction on the oestrous cycle of the rat.


Changes in pig cervical mucus in relation to the oestrous cycle.


Suppression of oestrus in grouped mice: the effects of various densities and the possible nature of the stimulus.


Epididymal lipid of the rat with and without testicular contribution.


Current concepts on the regulation of ovulation and corpus luteum function.


Hormonal influences on the maltase activities of testis and prostate of rats.


Changes in the pituitary FSH and LH levels during the oestrous cycle in the Indian water buffalo.


A study of follicular and luteal characteristics of the ovary at different stages of the oestrous cycle in the Surti buffalo heifer.


Splenectomy. A study of indications and sequelae.


Inhibition of tumor induction in chemical carcinogenesis in the mammary gland.


Effect of varied doses of x-irradiation on the thyroid histopathology in the Indian palm squirrel Funambulus pennanti (Wroughton).


Effect of tuberculous infection on mortality risk.


Gonadal changes in response to radiothyroidectomy and thiourea treatment in Mystus vittatus (Bloch).


Tuberculosis of the breast.

Tuberculosis of the breast.


Fine structure of tegumentary glands in Triturus cristatus (L.).


Isolation and purification of two phospholipases A from Bothrops venoms.


Human pancreatic enzymes: interaction of human trypsin with chicken ovomucoid.


DNA-dependent DNA polymerases from HeLa cell nuclei. II. Template and substrate utilization.


Difference between polylysine and polyarginine in changing DNA structure upon complex formation.


X rays and the structures of insulin.

X rays and the structures of insulin.


Utilization of amino acids by Rhodotorula glutinis.


Cystine, cysteine, and glutathione metabolism in normal and cystinotic fibroblasts in vitro, and in cultured normal amniotic fluid cells.


Surgical correction, using hypothermia, of an interventricular septal defect in the dog.


Effects of porcine calcitonin on calcium metabolism in osteoporosis.


Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays.


Radioimmunoassay of vasopressin: application to unextracted human urine.


Radioimmunoassay of serum thyrotropin: sensitivity and specificity.


A comparison of the pattern of steroid glucuronides and sulfates in maternal plasma, umbilical cord plasma and amniotic fluid. II.


Human growth hormone in urine.

Human growth hormone in urine.


Preparation and binding of antimicrosomal antibody-free LATS, and the effect of iodination on LATS biological activity.


A radioimmunoassay of thyroxine.

A radioimmunoassay of thyroxine.


Ultrastructural changes accompanying involution of the mammary gland in the albino rat.


Human prolactin. Evidence obtained by the bioassay of human plasma.


Effects of the interruption of amygdaloid and hippocampal afferents to the medial hypothalmus on gonadotrophin release.


Progesterone depot in threatened abortion.


The activity of human follicle-stimulating hormone preparations as measured by a response in vitro.


Retrograde amnesia for passive avoidance produced by stimulation of dorsal hippocampus.


The incubation effect in rats: skin resistance changes after footshock.


The development of interspecies aggression of rats towards mice during lactation.


Physical dependence on and tolerance to alcohol in the rat.


Duration and nature of retrograde amnesia produced by stimulation of caudate nucleus.


Neonatal administration of androstenedione, testosterone or testosterone propionate: effects on ovulation, sexual receptivity and aggressive behavior in female mice.


Temporal course of amnesia in rats after electroconvulsive chock.


The preputial glands as a source of aggression-promoting odors in mice.


Specificity of inhibition of lymphocyte activation in vitro by antiphytohemagglutinin antisera.


Nursing duration and suckling intensity: effects on plasma corticosterone, circulating leukocytes, and mammary nucleic acids.


Effect of a intrauterine foreign body during the estrous cycle on plasma progesterone in guinea pigs.


Studies on the blastogenic response of murine lymphocytes. I. Quantitative measurement of stimulation by phytohemagglutinin.


Effects on lactation of progesterone injections administered during late pregnancy in the rat.


Studies of formation of transplantation antibodies in mouse parabiosis.


The effect of an arginyl to a cysteinyl replacement on the uncoating behaviour of a spherical plant virus.


Essential and nonessential noncapsid reovirus proteins.


Studies on the mechanism of oxidative inactivation of plant viruses by o-Quinones.


A test for libido and serving ability in beef bulls.


Bronchogenic cyst arising from the trachea in an adult.


The significance of the multicomponent nature of cowpea chlorotic mottle virus RNA.


The effects of dichlorvos on several blood enzyme levels in the greyhound.


Enzootic pneumonia of pigs: the incidence of pneumonic lesions seen in an abattoir in New South Wales.


Changing patterns in pig production in Papua New Guinea.


Isolation and characterisation of Mycoplasma gallisepticum from a fowl.


Diseases of metabolism.

Diseases of metabolism.


Hereditary neuraxial oedema of calves.

Hereditary neuraxial oedema of calves.


Ions of the rare earths as possible reactivators of acetylcholinesterase inhibited by some organophosphorus compounds.


Intralymphatic therapy with immune lymphocytes.


Artefacts arising from the sedimentation of high molecular weight DNA on sucrose gradients.


Intra-arterial therapy of melanoma with dimethyl triazeno imidazole carboxamide (NSC-45388).


Intracellular potassium concentration during ammonia intoxication.


Local clearance by radioactive isotope in the knee joint under various conditions--with special reference to the mechanism of hydrops.


Intrauterine contraceptive device. A review and case report of perforation.


Treatment and prevention of syphilis and gonorrhea.


Passive sugar flux across frog jejunum in vitro.


Genetics of somatic fusion in a myxomycete: F 2  studies.


Disseminated adiaspiromycosis of the lungs in an 11-year-old boy caused by Emmonsia crescens.


Discussion: the overripeness hypothesis.


Comparison between the amniotic fluid and fetal urine in the last trimester of pregnancy.


Comparative aspects of courtship behavior in the ten-spined stickleback, Pygosteus pungitius (L.).


Mother-young relationship and ontogeny of behaviour in reindeer (Rangifer tarandus L.).


Social interaction and object manipulation in weaned pups of the northern elephant seal Mirounga angustirostris.


Agonistic behaviour in Mongolian gerbils.


Observations on the use of the exercise-wheel in relation to the social rank and hormonal conditions in the bank vole (Clethrionomys glareolus), and the Norway lemming (Lemmus lemmus).


Long-term food regulation in the obese and nonobese.


Effects of unilateral ovariectomy on follicular development and ovulation in cycling, aged rats.


Chronic consumption coagulopathy due to hemangiomatous transformation of the spleen.


Isolation and nature of intracellular peptides from a cephalosporin C-producing Cephalosporium sp. 1. Three peptides containing alpha-aminoadipic acid and cysteine have been obtained in small amounts from the mycelium of a Cephalosporium sp. 2. The peptides were precipitated as cuprous mercaptides together with glutathione and resolved from the latter and from each other by preparative paper electrophoresis and chromatography either in the sulphonic acid form or as S-sulphonyl derivatives. From the S-sulphonyl derivatives they were obtained in the thiol form. 3. One peptide (P3) was shown by amino acid analysis and the mass spectrum of the NS-ethoxycarbonyl derivative of its methyl ester to be delta-(l-alpha-aminoadipyl)-l-cysteinyl-d-valine. A second peptide (P2) contained alpha-aminoadipic acid, cysteine, valine and glycine, and the third peptide (P1) contained alpha-aminoadipic acid, cysteine, beta-hydroxyvaline and glycine.


Isoprenoid phenol and quinone precursors of ubiguinones and dihydroubiguinones (ubiguinones (H 2 )) in fungi. 1. Ten moulds and two yeasts were analysed for the presence of 2-polyprenylphenols, 2-polyprenyl(H(2))phenols, 6-methoxy-2-polyprenylphenols, 6-methoxy-2-polyprenyl(H(2))phenols, 6-methoxy-2-polyprenyl-1,4-benzoquinones, 6-methoxy-2-polyprenyl(H(2))-1,4-benzoquinones, 5-demethoxyubiquinones, 5-demethoxyubiquinones(H(2)), ubiquinones and ubiquinones(H(2)). 2. The organisms were found to be of three types: (a) those that contained only ubiquinones (Aspergillus fumigatus and Penicillium brevi-compactum) or ubiquinones(H(2)) (Alternaria solani, Claviceps purpurae and Penicillium stipitatum); (b) those that contained 5-demethoxyubiquinones and ubiquinones (Agaricus campestris, Aspergillus niger, Phycomyces blakesleeanus, Rhodotorula glutinis and Saccharomyces cerevisiae) or 5-demethoxyubiquinones(H(2)) and ubiquinones(H(2)) (Aspergillus quadrilineatus and Neurospora crassa); (c) one that contained 2-decaprenyl(H(2))phenol, 6-methoxy-2-decaprenyl(H(2))phenol, 6-methoxy-2-decaprenyl(X-H(2))-1,4-benzoquinone, 5-demethoxyubiquinone-10(X-H(2)) and ubiquinones(H(2)) (Aspergillus flavus). 3. Studies were made on the biosynthesis of ubiquinones and ubiquinones(H(2)) by Asp. flavus, Phyc. blakesleeanus and S. cerevisiae. These provided evidence that in Phyc. blakesleeanus 5-demethoxyubiquinone-9 is a precursor of ubiquinone-9 and that in S. cerevisiae 5-demethoxyubiquinone-6 is a precursor of ubiquinone-6. In addition they yielded results that may be interpreted as providing evidence that in Asp. flavus 6-methoxy-2-decaprenyl(X-H(2))-1,4-benzoquinone and 5-demethoxyubiquinone-10(X-H(2)) are precursors of ubiquinone-10(X-H(2)).


The infrared spectrum and water binding of collagen as a function of relative humidity.


Biosynthesis of peptides containing  -aminoadipic acid and cysteine in extracts of a Cephalosporium sp. 1. Three intracellular peptides found in small amount in a Cephalosporium sp. were rapidly labelled when dl-[(14)C]valine was added to a shaken suspension of the organism. More (14)C was incorporated into peptide P3, delta-(l-alpha-aminoadipyl)-l-cysteinyl-d-valine, than into peptide P2 (containing alpha-aminoadipic acid, cysteine, valine and glycine) or peptide P1 (containing beta-hydroxyvaline in place of the valine in peptide P2). 2. Peptides P3 and P2, but not peptide P1 were formed in a broken-cell system from the Cephalosporium sp. in the presence of delta-(l-alpha-aminoadipyl)-l-cysteine and dl-[(14)C]valine. No synthesis was observed in the presence of delta-(d-alpha-aminoadipyl)-l-cysteine or of dl-alpha-amino[(14)C]adipic acid and l-cysteinyl-l-valine or l-cysteinyl-d-valine. 3. The biosynthesis of these peptides was catalysed by the particulate fraction of the broken-cell system, whereas that of glutathione was catalysed by the supernatant fraction. 4. These results are discussed in relation to penicillin N and cephalosporin C biosynthesis.


Medium depletion and contact inhibition of replication: absence of a specific inhibitor.


The application of age response functions to the optimization of treatment schedules.


Arterial "triple hump" of idiopathic hypertrophic subaortic stenosis.


Induced differentiation of a neuroblastoma.


Specificities of prostaglandins B 1 , F 1  , and F 2   antigen-antibody reactions.


Isolation and characterization of a polysaccharide containing 3-O-methyl-D-mannose from Mycobacterium phlei.


The effects of respiratory acidosis in the chick embryo.


Effect of zinc, certain related dietary factors and age on the histamine content of chick tissues.


Gonadal malignancy in XY females.

Gonadal malignancy in XY females.


Antagonistic effect of arginine on zinc metabolism in chicks.


Wound healing in the fetal lamb.

Wound healing in the fetal lamb.


46 XX karyotype in four tissues of a true hermaphrodite.


Urine marking of cages and visual isolation as possible sources for error in behavioural studies of small mammals.


Life span of specified-pathogen-free (MRC category 4) mice and rats.


Rustic obstetrics.

Rustic obstetrics.


Some peculiar ultrastructural features of meningiomas.


Tuberculosis of cattle in Australia with particular reference to Queensland.


An evaluation of tick fever outbreaks in Northern Queensland in recent years.


The prophylactic effects of imidocarb against Babesia argentina and Babesia bigenima infections of cattle.


Infection of dairy cattle with Mycobacterium johnei in a partially vaccinated herd.


Observations on outbreaks of Battey type mycobacteriosis in pigs raised on deep litter.


Post-traumatic fluid accumulation in the abdomen of a dog.


Cysticercus ovis and kangaroos.

Cysticercus ovis and kangaroos.


Two unusual cases in pregnant mares.

Two unusual cases in pregnant mares.


Eimeria leuckarti in the horse.

Eimeria leuckarti in the horse.


Sump oil--a potent source of lead.

Sump oil--a potent source of lead.


Isolation of an agent capable of inducing pneumonia in swine.


Four species of Eimeria in pigs in Queensland.


Growth yields of Torulopsis utilis grown in continuous culture with glycerol or iron as the growth-limiting nutrient.


Studies on the interactions between purified bovine caseins and alkaline-earth-metal ions. 1. Alkaline-earth-metal cations at low concentrations form soluble complexes with bovine caseins. The relative order of binding capacities is: Mg(2+)>Ca(2+)>Ba(2+)>Sr(2+). 2. The cations interact with both free ionized carboxyl groups of aspartic acid and glutamic acid and with monoester phosphate groups covalently bound to serine and threonine; at low concentrations of the cations interactions are predominantly with the phosphate groups. 3. The order of binding capacities for purified components of the casein complex is: alpha(s1)-casein>beta-casein>kappa-casein.


The course of ketosis and the activity of key enzymes of ketogenesis and ketone-body utilization during development of the postnatal rat. 1. The highest blood concentrations of ketone bodies were found at 5 days of age, after which time the concentration fell to reach the adult value by 30 days of age. 2. Both mitochondrial and cytoplasmic hydroxymethylglutaryl-CoA synthase activities were detected, with highest activities being found in the mitochondria at all stages of development. Activity of the mitochondrial enzyme increases rapidly immediately after birth, showing a maximum at 15 days of age, thereafter falling to adult values. The cytoplasmic enzyme, on the other hand, increased steadily in activity after birth to reach a maximum at 40 days of age, after which time activity fell to adult values. 3. Both mitochondrial and cytoplasmic aceto-acetyl-CoA thiolase activities were detected, with the mitochondrial enzyme having considerably higher activities at all stages of development. The developmental patterns for both enzymes were very similar to those for the corresponding hydroxymethylglutaryl-CoA synthases. 4. The activity of heart acetoacetyl-CoA transferase remains constant from late foetal life until the end of the suckling period, after which time there is a gradual threefold increase in activity to reach the adult values. The activity of brain 3-oxo acid CoA-transferase increases steadily after birth, reaching a maximum at 30 days of age, thereafter decreasing to adult values, which are similar to foetal activities. Although at all stages of development the specific activity of the heart enzyme is higher than that of brain, the total enzymic capacity of the brain is higher than that of the heart during the suckling period.


Effect of  -actinin on actin viscosity.

Effect of  -actinin on actin viscosity.


Amino acid sequences around the cysteine residue of calf lens  -crystallin. 1. Calf lens alpha-crystallin was carboxymethylated with radioactive sodium iodoacetate to label the thiol group. 2. The protein was then digested with trypsin or alternatively fractionated in urea to obtain the acidic (A) chains, which were then digested with trypsin. Either procedure gave two radioactive peptides containing carboxymethylcysteine. 3. These two peptides were closely related: the longer form contained 28 amino acid residues, and the shorter lacked two residues at the N-terminal end of the longer form. 4. The amino acid sequence of the peptides have been determined. 5. No evidence for the presence of more than one cysteine residue/chain was found. 6. The question of the molecular weight of the chains is discussed.


The binding of carbon dioxide by horse haemoglobin. 1. Three modified horse haemoglobins have been prepared: (i) alpha(c) (2)beta(c) (2), in which both the alpha-amino groups of the alpha- and beta-chains have reacted with cyanate, (ii) alpha(c) (2)beta(2), in which the alpha-amino groups of the alpha-chains have reacted with cyanate, and (iii) alpha(2)beta(c) (2), in which the two alpha-amino groups of the beta-chain have reacted with cyanate. 2. The values of n (the Hill constant) for alpha(c) (2)beta(c) (2), alpha(2)beta(c) (2) and alpha(c) (2)beta(2) were (respectively) 2.5, 2.0 and 2.6, indicating the presence of co-operative interactions between the haem groups for all derivatives. 3. In the alkaline pH range (about pH8.0) all the derivatives show the same charge as normal haemoglobin whereas in the acid pH range (about pH6.0) alpha(c) (2)beta(c) (2) differs by four protonic charges and alpha(c) (2)beta(2), alpha(2)beta(c) (2) by two protonic charges from normal haemoglobin, indicating that the expected number of ionizing groups have been removed. 4. alpha(c) (2)beta(2) and alpha(c) (2)beta(c) (2) show a 25% decrease in the alkaline Bohr effect, in contrast with alpha(2)beta(c) (2), which has the same Bohr effect as normal haemoglobin. 5. The deoxy form of alpha(c) (2)beta(c) (2) does not bind more CO(2) than the oxy form of alpha(c) (2)beta(c) (2), whereas alpha(c) (2)beta(2) and alpha(2)beta(c) (2) show intermediate binding. 6. The results reported confirm the hypothesis that, under physiological conditions, haemoglobin binds CO(2) through the four terminal alpha-amino groups and that the two terminal alpha-amino groups of alpha-chains are involved in the Bohr effect.


Structural studies of modified cytochromes c by nuclear magnetic resonance spectroscopy.


Angular dependence of scattered light, rotary frictional coefficients, and distribution of sizes of associated oligomers in solutions of bovine liver glutamate dehydrogenase.


Some steroidal p-aminophenyl ethers and their N-methyl and NN-dimethyl analogues.


Some derivatives of NN'-biscarboxymethyl- and NN'-bis-( -carboxyethyl)-ethylenediamine.


Two new mould metabolites related to avenaciolide.


Rearrangement of 1 ,2-epoxy-3-oxo-5 -steroids.


Pyrazolopyrimidine nucleosides. Part I. Synthesis of pyrazolopyrimidine nucleosides related to the nucleoside antibiotic tubercidin.


Studies on lactams. Part XIV. The synthesis of a structural isomer of penicillin.


Heterocyclic studies. Part 23. 5-Trifluoromethylpyrimido(5,4-e)-as-triazines.


Pyrazolopyrimidine nucleosides. Part II. 7-Substituted 3- -D-ribofuranosylpyrasolo(4,3-d)pyrimidines related to and derived from the nucleoside antibiotics formycin and formycin B.


Seco-steroids. I. 15,16-Secoprogesterone.


Seco-steroids. 3. 5,6-Secoprogesterone.

Seco-steroids. 3. 5,6-Secoprogesterone.


Seco-steroids. II. 9,11-secoprogesterone.


Supernormal intraventricular conduction.


Significance of bivalence of antibody in viral neutralization. The role of bivalence of antibody in its capacity to neutralize virus was studied with rabbit antibodies to the bacteriophage, phiX174. Univalent Fab or Fab' fragments of IgG isolated from antiviral antisera obtained early in the immunization schedule had virtually no activity compared to that of the intact IgG. When the antibodies were isolated from antisera of the same rabbits several months later, the univalent fragments and IgG were essentially equal in activity. The results are interpreted on the basis that an IgG molecule, because of its bivalence, has a higher effective combining affinity (avidity) than a univalent fragment. After prolonged immunization, however, the affinity of univalent antibody becomes sufficiently high that it exceeds a threshold value, above which further increase in affinity, through bivalence, is no longer significant. The results could explain the variability in relative effectiveness of univalent antibodies observed in previous studies. These data, and the fact that F(ab')(2) fragments from either "early" or "late" antisera were as effective as IgG, indicate that fragment Fc is not a significant factor in neutralization. No differences in dissociation from the virus of univalent antibody from early and late antisera could be demonstrated by dilution at temperatures up to 47 degrees C. The attachment at sites of neutralization on the virus appears to be functionally almost irreversible in this system.


Blood coagulation initiation by a complement-mediated pathway. A variety of complement-activating substances, including inulin, immunoglobulin aggregates, bacterial endotoxins, and staphylococcal protein A, were found to initiate blood coagulation through a complement-mediated pathway. These substances markedly accelerated blood coagulation in normal rabbit blood. That this clot-promoting activity requires an intact complement system was demonstrated by an almost total lack of effect on blood from rabbits with an inherited deficiency of the sixth component of complement (C6). Small amounts of isolated C6 conferred to C6-deficient blood the ability to respond with accelerated coagulation upon activation of the complement system. In addition, it was determined that activation of complement through the previously described C3 activator system resulted in the initiation of blood coagulation. The participation of C1, C2, and C4 was not necessary.


Modulation of function of the activated first component of complement by a fragment derived from serum. I. Effect on early components of complement. An activity designated Kf can be separated from human serum and shown to give a 100-300% enhancement in the hemolytic activity of fully activated, fractionated C1. The enhancement of C1 activity is not because of activation of precursor C1 and it is not attributable to an effect on C1 binding. EAC42 or EAC4 intermediates interacted with C1Kf exhibit a greater T(max) and shorter Z(max) than when such intermediates are reacted with the same number of hemolytic units of C1. C3 consumption by the EAC1Kf42 intermediate greatly exceeds that of the EAC142 intermediate produced from the same EAC4 cells by comparable inputs of the other two complement components. Taken together, these findings suggest that Kf-treated C1 achieves more efficient utilization of C4 and C2 to create a larger number of 42 sites as appreciated on the intermediates by shorter T(max) and a greater Z(max), and an increased capacity to utilize C3. The capacity of Kf to enhance C1 upon introduction into whole serum of a patient with hereditary angioedema (HAE) in a manner comparable to its effect on fractionated C1 suggests that the effect of Kf may be pertinent to certain pathophysiologic conditions of man.


Penta X (49,XXXXX) chromosome constitution: a case report.


Pulmonary valve insufficiency in a case of tetralogy of Fallot after Brock's operation: correction by heterologous aortic graft.


Studies on the Y chromosome in human males from fertile and infertile couples.


Detection of the red cell acid phosphatase variant allele in Japanese.


A technical note on the antenatal chromosome analysis by transabdominal fetal skin biopsy.


The effect of imipramine and selected drugs on attack elicited by hypothalamic stimulation in the cat.


Cholinergic and neuroleptic induced catalepsy: modification by lesions in the globus pallidus and substantia nigra.


Stress during acquisition and T-maze choice behavior in extinction.


Obstetrics in the Transkei.

Obstetrics in the Transkei.


Angiosarcoma of the breast.

Angiosarcoma of the breast.


Cataract surgery in dogs.

Cataract surgery in dogs.


Transport of monosaccharides in Rhodotorula gracilis in the absence of metabolic energy.


Measures of the aggression of parental male three-spined sticklebacks.


The conversion of cyclamate into cyclohexylamine by gut bacteria.


'Fingerprinting' studies on  35 S-labelled mammalian-cell ribosomal proteins.


Methylation of newly synthesized and older deoxyribonucleic acid.


Determination of the operational molarity of solutions of bovine alpha-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorometric titration.


Interaction of poly-L-tyrosine with nucleic acids. I. Formation of complexes.


A cytoplasmic protein from Neurospora crassa resembling membrane proteins.


Studies on the solubilized ribonucleic acid polymerase from rat ventral prostate gland. 1. By using ultrasonic treatment in media of high ionic strength, the RNA polymerase activities associated with prostatic nuclei and nucleoli can be completely solubilized. Such enzyme preparations are entirely dependent on the provision of added DNA for full activity. 2. The solubilized enzymes from the nucleolar and extranucleolar regions can be separated by ion-exchange chromatography. 3. Based on differences in the optimum DNA templates, pH optima and the effects of ammonium sulphate on the activities in vitro, Mn(2+)- and Mg(2+)-specific enzymes are associated with both the nucleolar and extranucleolar regions of prostatic nuclei. 4. Androgenic hormones administered in vivo have a particularly pronounced effect on the activity of Mg(2+)-dependent enzyme associated with the isolated prostatic nucleolus. 5. Time-course experiments in vivo show that androgens induce a rapid stimulation of the solubilized Mg(2+)-dependent nucleolar enzyme before a pronounced activation of nucleolar chromatin can be measured. 6. The implications of these findings to the mechanism of action of androgenic steroids are discussed.


Studies on the structural requirements of substrate protein for protein methylase II.


Isoaccepting transfer ribonucleic acids in specialized mammalian tissues.


Isolation, identification, and specific localization of di-2-ethylhexyl phthalate in bovine heart muscle mitochondria.


Action of chloroform and its chlorinated analogs on hemoproteins.


Evidence for the binding of pyridoxal 5'-phosphate in a hydrophobic region of glycogen phosphorylase b dimer.


Spectral properties of cobalt carboxypeptidase. The effects of substrates and inhibitors.


Enhancement of polyribosome formation and induction of tryptophan-rich proteins by gibberellic acid.


Polyuridylic acid binding by protein from Ehrlich ascites cell ribosomes and its inhibition by aurintricarboxylic acid.


Control of DNA replication by protein synthesis at defined times during the S period in Physarum polycephalum.


Amenorrhea after the pill.

Amenorrhea after the pill.


Medical Aspects of the Compton report.

Medical Aspects of the Compton report.


Changes in the DNA synthetic period during the phase of rapid growth in cultured diploid fibroblastic cells.


Comparison of aminotransferase activities as determined by the original, revised and optimum spectrophotometric methods.


Chromosomal abnormality in a phenotypically and clinically normal dog.


Cell cooperation in antibody induction. The susceptibility of helper cells to specific lethal radioactive antigen.


The effect of interferon and interferon inducers on avian influenza.


Colonization of humans by Mycoplasma canis.


Human psittacosis in the United States-1970.


Triazenes of phenylbutyric, hydrocinnamic, phenoxyacetic, and benzoylglutamic acid derivatives.


Synthesis of compounds related to metabolites of trimetazidine in rabbits.


Integration of human genetic studies in clinical medicine.


Serum antibody to double-stranded RNA and DNA in patients with idiopathic and secondary uveitis.


Changes in  133 Xe clearances resulting from electrically induced muscle contractions. I. Study in dog.


Hydrogenated marine fat, effect on growth and liver weight in young rats given a high fat, low protein ration.


Operandum attacking may contribute to schedule effects on response rate.


Activation of coagulation factor X by insoluble trypsin.


The mitochondrial ribosome of baby-hamster kidney cells.


Amino acid transport and mental retardation.


Mechanism of action of specific antiserum on Pasteurella septica. Selective inhibition of net macromolecular synthesis and its reversal by iron compounds.


Heterophile antibody levels in the white, Asian and Bantu populations of Southern Africa.


The carrier effect in the secondary response to hapten-protein conjugates. 3. The anatomical distribution of helper cells and antibody-forming-cell-precursors.


Dosimetry of 129 Cs and 131 Cs.

Dosimetry of 129 Cs and 131 Cs.


Proteins made in the mammalian cell cycle.


Some less familiar drugs of abuse.

Some less familiar drugs of abuse.


Medical research: WHO's programme scrutinized.


Osmotic and ionic conditions in pelagic teleost eggs.


Plasma corticosterone levels during active avoidance learning.


Effect of acetylcholine on the electrical and mechanical responses of the guinea pig vas deferens to nerve stimulation.


Report of Inter-Society Commission for Heart Disease Resources. III. Cardiovascular Disease--long-term care. Community resources for the management of patients with rheumatic heart disease.


A survey of deaths in Rhodesia caused by animals.


The incorporation of 4- 14 C-cholesterol into different cholesterol esters of the blood serum in man, guinea-pig, rat and rabbit.


Effects of ovariectomy and of oestrogen administration on the decrease in pituitary prolactin content which occurs on the afternoon of pro-oestrus in the rat.


Purification of thymidylate synthetase from Ehrlich ascites carcinoma cells.


5'-adenosine monophosphate aminohydrolase. Evidence for anomalous substrate saturation kinetics at low enzyme concentrations.


Involvement of a tyrosine residue in the activity of bovine pancreatic deoxyribonuclease A.


Allosteric properties of skeletal muscle pyruvate kinase.


Total synthesis of polymethoxyoestrane compounds. I. Synthesis of ( )-2,3,4-trimethoxyoestra-1,3,5(10)-trien-17 -ol and related compounds.


Total synthesis of polymethoxyoestrane compounds. II. Synthesis of ( )-2,4-dimethoxyoestra-1,3,5(10)-trien-17 -ol.


Amino-acids and peptides. XXXIV. Anchimerically assisted coupling reactions: the use of 2-pyridyl thiolesters.


Polypeptides. XII. The preparation of 2-pyridyl esters and their use in peptide synthesis.


A synthesis of 2-O-methyl-L-lyxose, a component of everninomicins B and D.


Effects of fighting, genotype, and amphetamine sulfate on body temperature of mice.


Truly random and traditional control procedures in CER conditioning in the rat.


Retrograde amnesic and facilitative effects of ether on learning and generalization gradients.


Experience of the use of desamino-oxytocin buccal tablets as a method of inducing labour, and of a scoring system for evaluation of readiness for labour.


Early malignant disease of the chorion.

Early malignant disease of the chorion.


Benign gynaecological tumours and radioisotope renography.


A special suction-tube for post-partum evaculation of the uterus.


The cardiac blur sign of the post infarction myocardial scar.


Abdominal and retroperitoneal sonography.


Rapid and effective removal of sodium dodecyl sulfate from proteins.


Initial steps in pyrimidine synthesis in Ehrlich ascites carcinoma.


The number, distribution and functional implication of sulfhydryl groups in rabbit muscle aldolase.


Response of nucleoside diphosphate kinase to the adenylate energy charge.


Serum LH levels and luteal weight in ewes following a single injection of estradiol.


Abnormal spermiogenesis in quaking, a myelin-deficient mutant mouse.


The kinetics of granulosa cells in developing follicles in the mouse ovary.


Rebound phenomena in thyroid function after withdrawal of propylthiouracil in growing chicks.


[Hormonal conditions necessary for evolution of the ovary in the pupa of Tenebrio molitor (Coleoptera)].


Fatty acid composition of Cladosporium resinae grown on glucose and on hydrocarbons. Cladosporium resinae was grown in submerged cultures on glucose; on Jet-A commercial aviation fuel; and on a series of n-alkanes, n-decane through n-tetradecane. Cell yield was greatest on glucose and least on Jet-A; n-alkanes were intermediate. Among n-alkanes cell yield decreased as chain length increased, except for n-dodecane, which supported less growth than n-tridecane or n-tetradecane. The total fatty acids of stationary-phase cells were analyzed by gas-liquid chromatography. In all cases the predominant fatty acids were 16:0, 18:1, and 18:2. The fatty acid composition of glucose-grown cells was similar to that of hydrocarbon-grown cells. Cells grown on n-tridecane or n-tetradecane yielded small amounts of acids homologous to the carbon source, but a similar correlation was not noted for n-decane, n-undecane, or n-dodecane. Cells grown on n-undecane or n-tridecane contained more odd-carbon fatty acids than cells grown on the other substrates, and the effect was more pronounced in n-tridecane-grown cells. Thus, the fatty acids of this organism are derived chiefly from de novo synthesis rather than from direct incorporation of oxidized hydrocarbons. The extent of direct incorporation increases as the chain length of the hydrocarbon growth substrate is increased.


Purification and characterization of the L component of Streptococcus zymogenes lysin. By utilizing conventional techniques of pressure ultrafiltration, gel filtration chromatography, diethylaminoethyl cellulose chromatography, and preparative polyacrylamide electrophoresis, the L component of the group D lysin produced by Streptococcus zymogenes strains has been purified to a state of homogeneity as determined by the techniques of disc-gel electrophoresis at pH 9.3 and 4.3 and isoelectric focusing. The L component was found to be a protein possessing a molecular weight of 11,000 with a slight net negative charge at physiological pH.


Synthesis and some properties of an actin-like nuclear protein in the slime mold Physarum polycephalum. A protein was extracted from isolated nuclei of the slime mold Physarum polycephalum which could be labeled with radioactive precursors only during G(2) phase. The native protein was purified by extraction in low-ionic-strength buffer [10 mm tris(hydroxymethyl)aminomethane-hydrochloride] of isolated nuclei and by preparative polyacrylamide gel electrophoresis. It was extracted from isolated nucleoli. Its electrophoretic properties in three different polyacrylamide gel systems, its molecular weight (44,000 +/- 3,000), its precipitability by vincaleucoblastine, a vinca alkaloid, and its aggregation properties suggested that it might be actin. In a direct comparison with slime mold actin purified from the cytoplasm, no difference could be found between the two proteins in all these characteristics. The synthesis of cytoplasmic actin was not found to occur exclusively during G(2) phase. This suggested that nuclear actin was either synthesized independently from cytoplasmic actin or transported into the nuclei exclusively during G(2) phase. The possible role of nuclear actin during intranuclear mitosis is discussed.


Scanning electron microscopy of intact Trichoderma colonies. Scanning electron microscopy revealed a clear distinction between hyphal types and enabled early detection of hyphal initiation. Stages in the photoinduced differentiation in Trichoderma leading to conidiation could thus be studied.


Effects of various drugs on hemolytic activity of Streptococcus zymogenes. Drugs known to interrupt the chain of protein synthesis (streptomycin, chloramphenicol, ethidium bromide) appeared to affect production of the group D lysin by Streptococcus zymogenes by inhibiting growth. Drugs which block cell wall synthesis (vancomycin, bacitracin, d-cycloserine, and phosphonomycin) inhibited lytic activity by a mechanism independent of growth. Bacitracin appeared not to have a major effect on lysin production but elicited the production of an inhibitor of lytic activity.


Extractives from poisonous British plants. I. The structure of alpinumisoflavone, a new pyranoisoflavone from Laburnum alpinum J. Presl.


Synthesis of peptides containing N-2-aminoethylglycine--'reduction analogues'.


Studies in myocological chemistry. XXVII. Reinvestigation of the structure of purpurogenone, a metabolite of Penicillium purpurogenum Stoll.


Studies in mycological chemistry. 28. Isolation and structure of deoxypurpurogenone, a minor pigment of Penicillium purpurogenum Stoll.


1-phenethylisoquinoline alkaloids. II. The structures of alkaloids from Colchicum cornigerum (Sweinf.) Tackh. et Drar.


Hydroxyindole-O-methyltransferase. V. Effects of substituents on hydrolysis of N-acyltryptamines in rats.


Hydroxyindole-0-methyltransferase. VI. Inhibitory activities of substituted benzoyltryptamines and benzenesulfonyltryptamines.


Regional conference on drug trafficking.


Isolation and characterization of cytotoxic principles from Hyptis verticillata jacq.


The chemical nature of Shigella flexneri group antigen factor 6.


On the male of Avioserpens multipapillosa Singh, 1949 from Ardeola grayii.


A new species of the genus Anaporrhutum ofenheim, 1900 from the buccopharyngeal region of Mobula diabolus from Arabian sea.


On a remarkable new nematode, Aliascaris indica gen. et sp. nov. (Ascarididea: Heterocheilidae) from a marine fish, Trygon sephen.


Observations on trichostrongylid worms from Indian birds, including a description of two new species.


Subcapsular haematoma of the liver in pregnancy.


Method of inserting a nasogastric tube in the anesthetized or comatose patient.


Respiratory care in acute botulism: a report of four cases.


Anesthesia and cardiomyopathies: report of two cases.


Antiemetic effectiveness of haloperidol in human volunteers challenged with apomorphine.


Regional anesthesia for surgery of the shoulder. Guest discussion.


Respiratory factors in the management of patients after open-heart surgery.


Regional anesthesia for surgery on the shoulder.


Current usefulness of ketamine in anesthetic practice.


Cardiovascular effects of three technics for inducing hypotension during anesthesia.


Simultaneous systemic and hepatic hemodynamic measurements during high peridural anesthesia in normal man.


Simultaneous systemic and hepatic hemodynamic measurements during high peridural anesthesia in normal man. Guest discussion.


Effect of neostigmine on cardiac rhythm in digitalized dogs.


Clinical application of the lactic dehydrogenase zymogram in anesthesia. Guest discussion.


Malignant hyperthermia with subsequent uneventful general anesthesia.


Malignant hyperthermia with subsequent uneventful general anesthesia. Guest discussion.


Body temperature and disappearance of lidocaine in newborn puppies.


Thoughts about medical writing. 8. Loaded language.


A hazard in the use of an Ayre T-piece.

A hazard in the use of an Ayre T-piece.


Humidity in a semiopen system for intact anesthesia. Guest discussion.


Hyperpyrexia in the operative and immediate postoperative period.


Body metabolism during general anesthesia without superimposed surgical stress.


The antagonism of morphine anesthesia by naloxone.


Antagonism of morphine anesthesia by naloxone. Guest discussion.


Ketamine for blind nasal intubation.

Ketamine for blind nasal intubation.


Intra-arterial injection of secobarbital sodium into the brachial artery: sequelae of a "hand trip".


Ethyl alcohol and morphine: a dissociative anesthetic technic.


Cardiac press adapter for the operating room.


Humidification in a semiopen system for infant anesthesia.


Ethyl alcohol and morphine: a dissociative anesthetic technic. Guest discussion.


Pathological findings in viper bites.

Pathological findings in viper bites.


Degradation of DNA in high-intensity focused ultrasonic fields at 1 MHz.


Demodectic mange of swine.

Demodectic mange of swine.


Parotid salivary gland cyst and calculus in a dog.


Thoracic wall reconstruction in dogs.

Thoracic wall reconstruction in dogs.


Nonsurgical removal of calculi from the urethra of male dogs.


An efficient procedure for the isolation of polyribosomes from tissue culture.


Spontaneous recovery after subinvolution of placental sites in a bitch.


Perineal urethrostomy in cats.

Perineal urethrostomy in cats.


Incorrect animal identification--it could happen to you.


What is your diagnosis?

What is your diagnosis?


Canine factor XI (plasma thromboplastin antecedent) deficiency.


Antihypertensive action of renomedullary prostaglandins (PGE 2  and PGA 2 ) in the spontaneously hypertensive rat (SH rat): evidence for an indirect blood-pressure--lowering effect.


Metabolic control of the kinetic properties of lipoprotein lipase.


Isolation of human factor IX by immunoadsorption.


Synthesis and fluorescence polarization analysis of an organomercurial derivative of actin.


Inhibition of prolactin secretion and successful therapy of the Forbes-Albright syndrome with L-dopa.


The true hermaphroditism. A case report.


Pharmacodynamics of chemotherapeutic effects: dose-time-response relationships for phase-nonspecific agents.


Antagonistic activities of derivatives of cystinyl-tyrosyl-tyrosine to actions of oxytocin.


Immunoassay for human calcitonin. I. Method.


Studies of diabetic instability. I. Immunoassay of human insulin in plasma containing antibodies to pork and beef insulin.


Physiologic investigation of posterior pituitary binding proteins neurophysin I and neurophysin II.


Mental health services to the aging in Virginia--some findings and clinical impressions presented for consideration.


Small pelvic outlet associated with underdevelopment of the urinary tract and other anomalies.


Purification of hydroxyproline-containing protein from human serum.


The subcellular distribution of colchicine-binding protein(s) ( microtubule protein') in rat brain.


Influence of acid citrate in stored blood on the level of electrolytes in plasma.


Partial characterization of pectinolytic enzymes of Bacteroides ruminicola isolated from the rumen of a sheep.


The extraction of a protein fraction rich in glycine, serine, tyrosine, and phenylalanine from Merino wool.


The dipole moment of myoglobin.

The dipole moment of myoglobin.


The inheritance of neurotic traits: a twin study of the Middlesex Hospital Questionnaire.


Grid test of thought disorder.

Grid test of thought disorder.


Personality profiles related to emotional stress in the initial year of medical training.


A student-initiated curricular option in behavioral pharmacology.


Renal effects of calcitonin and parathyroid extract in man. Studies in hypoparathyroidism. To clarify the controversial renal action of calcitonin (CT) and a possible interrelationship between CT and parathyroid hormone, eight patients with untreated surgical hypoparathyroidism were studied. Various calcitonins, i.e. extracted porcine, synthetic porcine, synthetic human, and synthetic salmon CT in doses of 150 Medical Research Council U or 1.5 mg were infused over a 3 hr period. Subsequently, six of the same subjects received 500 USP U parathyroid extract (PTE) (Eli Lilly & Co., Indianapolis, Ind.) in 3 hr and later a combination of CT and PTE. In addition, two patients were given an infusion of ammonium phosphate with the aim of producting a phosphaturia of comparable degree as seen after CT and PTE, thus differentiating hormonal from nonhormonal influences on cation excretion. A protocol of serial clearance (C) studies using the patients as their own controls was followed. Serum and urinary inorganic phosphate (P), calcium (Ca), magnesium (Mg), sodium (Na), potassium (K), and creatinine (Cr) were determined and the clearance values calculated. All CT peptides caused a uniform, immediate and significant increase of C(P), C(Na), C(K), C(Ca), and C(Mg), PTE evoked a rise of C(P), C(Na), and C(K), but C(Ca) and C(Mg) were reduced, the Ca and Na figures being not statistically significant. The administration of both CT and PTE resulted in a summation of individual hormone effects on Ca and Mg excretion. Phosphate infusion on the other hand induced an isolated phosphaturia but no concomitant changes of the urinary cations.The hypoparathyroid data demonstrate that calcitonin enhances urinary elimination of P, Na, K, Ca, and Mg independently of parathyroid action, CT and PTE act qualitatively similarly on P, Na, and K excretion, while an antagonism seems to exist for the renal handling of Ca and Mg.


Radioassay of cortisol and corticosterone by a modified competitive protein-binding method.


Comparison of pigments in carpophores and saprophytic cultures of paxillus panuoides and paxillus atrotomentosus.


Effect of certain vitamins on the growth and sporulation of Curvularia lunata (Wakker) Boedijn.


Mycoflora of developing peanut pods in Oklahoma.


The shift to the left.

The shift to the left.


The incidence of fungi in the throat.

The incidence of fungi in the throat.


Catheter biopsy of the heart.

Catheter biopsy of the heart.


Exfoliative cytodiagnosis as a screening test in bladder tumours.


Etiology and electrocardiographic features of the billowing posterior mitral leaflet syndrome. Analysis of a further 130 patients with a late systolic murmur or nonejection systolic click.


Methotrexate for prophylaxis of choriocarcinoma.


Denaturation of globular proteins by guanidine thiocyanate. II. Intrinsic viscosities in 4.5 M quanidine thiocyanate solutions.


Hydrogen exchange in proteins. Equilibrium and kinetic isotope effects in bovine plasma albumin studied with tritium and deuterium.


The electric birefringence buildup curve as applied to the determination of the dipole moment of soluble collagen.


Cross-reactivity of some rabbit anti-human lysozyme sera with gallinaceous lysozymes.


Cardiofacial syndrome.

Cardiofacial syndrome.


Unusual particles in splenic disorders.

Unusual particles in splenic disorders. Virus-like particles have been seen on electronmicroscopic examination of four spleens surgically removed for haematological disorders-three cases of idiopathic thrombocytopenic purpura and one case of haemolytic anaemia. The particles were approximately spherical and 50-60 nanometres in diameter.


Vomiting, diarrhoea, and infection.

Vomiting, diarrhoea, and infection.


Hamster-hair hypersensitivity.

Hamster-hair hypersensitivity.


Difficulty in swallowing as an early sign.


A study of lens construction and use.

A study of lens construction and use.


Alpha and beta globin messenger ribonucleic acid. Different amounts and rates of initiation of translation.


The role of superoxide and hydroperoxide in the reductive activation of tryptophan-2,3-dioxygenase.


Amino acid sequence and sequence variability of the amino-terminal regions of lysine-rich histones.


Properties of the insulin receptor of isolated fat cell membranes.


Snake venom toxins. The amino acid sequences of toxins   and   from Naja nivea venom and the disulfide bonds of toxin  .


Colony-forming ability of human immunoglobulin-producing cells.


Canine histiocytic ulcerative colitis. The early lesion and its progression to ulceration.


Inhibition of mitosis and macromolecular synthesis in rat embryo cells by Kilham rat virus. The effects of Kilham rat virus multiplication were studied in cultured rat embryo cells to examine the mechanisms by which virus infection might be related to developmental defects in rats and hamsters. The virus was found to inhibit motosis and deoxyribonucleic acid (DNA) synthesis within 2 to 10 hr after infection. However, total ribonucleic acid synthesis was relatively unaffected until about 20 hr after infection, and total protein synthesis did not decline significantly until loss of viable cells was apparent in the cultures. No effect on chromosomes was detected. The effect of Kilham rat virus on DNA synthesis appears to be due to inhibition of macromolecular synthesis rather than to an inhibition of uptake of precursors into cells. The effect of the virus on mitosis may be an addition to the effect on DNA synthesis, since mitosis is inhibited even in cultures in which cells are able to divide at the time of infection and which have presumably completed DNA synthesis.


Changes in adult Nippostrongylus brasiliensis during the development of immunity to this nematode in rats. 2. Total lipids and neutral lipids.


The chemical composition and some properties of the egg layers in Hymenolepis diminuta eggs.


Congenital tuberculosis in a small premature baby.


Preparation of human C-peptide.

Preparation of human C-peptide.


Radioimmunoassay of human plasma calcitonin.


Molecular weight estimation of immunoglobulin subunits of polyacrylamide gel.


Magnitude estimation and relative aversiveness of anxiety: phobia.


Effects of compound 48-80 on immune haemolysis: enhancement of C1 site formation and inhibition of C4 site formation.


Fears as attitudes: experimental reduction of fear through reinforcement.


Studies on monoene fatty acid isomers in hydrogenated fish oils.


Tuberculosis case-finding in the seventies.


Psycho-educational service for elementary schools: a preventive systems approach.


[Enzymatic studies of D-arabinosone. VII. Antioxidant in swine liver against the autoxidation of D-arabinosone].


Mental health and the physician: who worries about his?


Maryland's new mental hygiene law.

Maryland's new mental hygiene law.


Glycoprotein synthesis in cells infected with vaccinia virus. II. A glycoprotein component of the virion.


Undisturbed release of influenza virus in the presence of univalent antineuraminidase antibodies.


Tobacco mosaic virus strains extracted from conidia of powdery mildews.


Treatment of experimentally induced oleander poisoning.


Thiopropazate hydrochloride in persistent dyskinesia.


Pteridine studies. XLI. New routes to 4-aminopteridines via 3-(dimethylaminomethyleneamino)pyrazine-2-carbonitrile and related compounds.


6-alkyl derivatives of 3-(3,4-dihydroxyphenyl)alanine (Dopa). I. Synthesis via oxazolinones.


Cyano-13-epicobalamin(neovitamin B 12 )and its relatives.


The total synthesis of a nuclear analogue of the penicillin--cephalosporin antibiotics.


Syntheses of L-vallarose (6-deoxy-3-O-methyl-L-altrose) and D-digitalose (6-deoxy-3-O-methyl-D-galactose).


Mechanism of action of rat liver DNA methylase. II. Interaction with single-stranded methyl-acceptor DNA.


Tests for comparing related amino-acid sequences. Cytochrome c and cytochrome c 551 .


Programmed synthesis of deoxyribonucleic acid during the cell cycle.


Trypsin sensitivity of mammallian cells grown in a serum-free medium.


Selection procedures for mammalian cells in monolayer culture.


pH stat assay for guanine aminohydrolase.


Use of chemical ionization mass spectrometry in analysis of amino acid phenylthiohydantoin derivatives formed during Edman degradation of proteins.


Nucleohistone content during aging in tissue culture.


An improved method for colorimetric determination of proline with isatin.


Observations on the labeling of fringes for ultracentrifugation with interference optics.


Solubilization of iron-containing minerals by soil microorganisms. Eighty-eight strains of microorganisms were isolated from soils collected in northern and southern Chile, and 10 fungi which showed the highest solubilizing action upon the iron in granodiorite were then selected. These fungi were incubated with the following iron-containing minerals: augite, hornblende, biotite, magnetite, hematite, and the igneous rock granodiorite. The solubility of iron in these minerals depended on their nature, crystalline structure, the concentration of metabolic products, or all three. Complex formation could be the mechanism involved, as a strong cation-exchange resin was not able to extract Fe from culture solutions. This conclusion is also confirmed by the R(F) values obtained by thin-layer chromatography of iron-containing culture solutions.


Natural and induced synchronous cultures.


Cultural estimation of yeasts on seaweeds. Five per cent suspensions of freshly harvested seaweeds were used as an inoculum to develop a selective medium for epiphytic yeasts. Conditions for satisfactory yeast growth and visualization as red colonies on membrane filters were obtained by supplementing a basal glucose-Trypticase-yeast extract-agar at pH 7.0 with 100 mg each of chloramphenicol and 2,3,5-triphenyl tetrazolium chloride per liter. Maximal counts were obtained by triturating the algae in prechilled (4 C) seawater with a blender for 2 to 5 min. Inhibitory phenolic materials released from phaeophytes during this process were removed with a modified Cholodny filtration. A preliminary survey indicated that yeasts were epiphytic on all nine species of seaweeds and that maximal populations occurred on the chlorophytes and rhodophytes especially during the periods of warmer water.


Effect of controlled atmosphere on growth of mold on synthetic media and fruit. Growth of seven spoilage molds on agar plates at several temperatures in both controlled atmosphere (CA) and in air was studied. Each mold responded somewhat differently to CA at each temperature; however, there were some general tendencies. The lag phase was generally increased by CA and, in some cases, was substantially extended when incubation was just above the minimum growth temperature. The mycelial structure of molds seems to be different when grown in CA than when grown in air. With only two exceptions of 24 holding conditions, the maximum amount of mycelia was always less in CA than in air. Spore development varied with each mold at each temperature; generally, it was considerably less in CA than in air. CA storage of cherries above 34 F (1 C) did not retard mold infection to any extent; at 34 F, mold growth was inhibited and storage life was extended several days as compared to air storage. CA storage of strawberries at 34 F resulted in a mold-free product after 7 days of incubation, whereas the air-stored berries were slightly infected. However, when mishandled berries showing some mold growth were stored at 34 F, CA did not stop further mold growth.


Isolation of inhibitory factor in raw milk whey active against propionibacteria. Preparative isolation of the active component(s) in skim milk whey inhibitory for propionibacteria was made by using (NH(4))(2)SO(4) salt fractionation. The crude preparation was further purified by Sephadex G-100 column separation. Disc-gel electrophoresis of the active peak from the Sephadex elution pattern (peak I) showed that this fraction contained almost all of the immune globulin in the column sample. The biologically inactive peaks did not contain any immune globulin. Starch-gel electrophoresis of the active peak revealed the presence of three separate immune globulin fractions. A correlation was also observed between hemolytic reaction of propionibacterial strains and relative resistance to whey inhibition. The investigation showed that one of the immune globulins of milk, pseudoglobulin, was mainly responsible for the suppressive activity of whey.


Role of pH and nitrogen limitation in the elaboration of the extracellular polysaccharide pullulan by Pullularia pullulans. During the growth of the yeastlike fungus Pullularia pullulans on glucose as sole carbon source, the cell-mass does not increase concomitantly with the elaboration of the extracellular polysaccharide pullulan, but precedes it. The conditions generated in the culture medium which activate the secretion of polysaccharide have been sought for, and, in particular, the roles of extracellular pH and nitrogen limitatation are examined.


Utilization of carbon sources by Pullularia pullulans for the elaboration of extracellular polysaccharides. The yeastlike fungus Pullularia pullulans utilizes simple mono- and disaccharides both in the production of cell mass and the elaboration of extracellular polysaccharide. The utilization pattern of these sugars and the effect obtained by varying the pH of the medium are studied, and the ability of the organism to utilize and elaborate extracellular polysaccharides from noncarbohydrate sources is explored.


Lack of toxicity of Helminthosporium maydis-invaded corn and culture filtrates to chicks and mice. Six isolates of Helminthosporium maydis, obtained from southern leaf blight-damaged corn, were grown separately on autoclaved corn and fed to chicks and mice to evaluate their toxigenicity. Two-, three-, and four-week-old culture filtrates from three pathogenic isolates grown separately on modified Fries medium were also evaluated for toxigenicity. None of the invaded corn samples or culture filtrates affected the weights of chicks or mice when compared to controls. Postmortem examinations did not reveal significant gross lesions. H. maydis was not toxigenic under our experimental conditions.


Staphylococcus epidermidis BV: antibiotic resistance patterns, physiological characteristics, and bacteriophage susceptibility. Staphylococcus epidermidis BV is a group of mannitol-fermenting coagulase-negative staphylococci characterized by multiple antibiotic resistance, very similar biochemical characteristics, and phage susceptibility. Clinical isolates belonging to this group are resistant to most antibiotics tested, including oxacillin, lincomycin, and novobiocin. The only antibiotic to which all tested strains are sensitive is vancomycin. Common biochemical traits of the tested S. epidermidis BV strains include fermentation of trehalose and ribose, phospho-beta-glucosidase activity, growth on synthetic medium with amino acids as carbon source, and lack of deoxyribonuclease, phosphatase, lipase, and gelatinase activity. Some of these characteristics appear more frequently in mannitol-positive control strains than in mannitol-negative strains. S. epidermidis BV strains carry lysogenic phages with a host range restricted to this group. These phages allow the differentiation of individual strains.


Parvoiruses as contaminants of permanent human cell lines. I. Virus isolation from 1960-1970.


The action of pure pig pancreatic lipase upon esters of long-chain fatty acids and short-chain primary alcohols.


Electron microscopic study on reassembly of plasma high density apoprotein with various lipids.


Changes of the positional distribution of fatty acids in phosphoglycerides during development of insects.


Bacteriocine typing of Klebsiella spp.

Bacteriocine typing of Klebsiella spp. One hundred and six strains of Klebsiella spp were examined for their ability to produce bacteriocine. Nine of these, together with one strain from the National Collection of Type Cultures, were selected and used to type Klebsiella strains from various sources. Strains were typed by testing their sensitivity to bacteriocines produced by the standard set of 10 strains. Eight hundred strains were tested and 77% of these were typable and could be divided into a relatively large number of groups, some of which occurred consistently more frequently than others.This simple method has been shown to have some value in epidemiological investigations.


Papillon Le Fevre syndrome. Report of a case in U.A.R.


The relation between egg production and worm burden in experimental schistosomiasis. II. Duration of infection.


Panel discussion. Hypophysectomy.

Panel discussion. Hypophysectomy.


Two rhino mice (Mus musculus) from Minnesota.


Virus RNA and protein synthesis in cells infected with different strains of Newcastle disease virus.


Euderma maculatum from California infected with rabies virus.


Serial luteinizing hormone measurements in cannulated, unanesthetized rats.


The fine structure of intercellular junctions in the developing retina of Xenopus laevis.


Effect of electrical stimulation on the fluorescence intensity of catecholamine-containing tuberal nerve cells. 1. By means of a microfluorimetric technique, the intensity of the catecholamine fluorescence was measured in nerve cells of the arcuate and periventricular hypothalamic nuclei of ovariectomized rats pre-treated with oestrogen and progesterone. In such animals the fluorescence intensity is in the range of the lowest intensities that were observed during the oestrous cycle.2. Unilateral intermittent electrical stimulation of the arcuate nucleus or of the medial preoptic area induced an acute increase of the fluorescence intensity in the cell bodies of the tuberal catecholamine-containing nerve cell group. The change was already manifest 5 min after the onset of stimulation and within 10 min the mean fluorescence intensity reached levels that are among the highest so far observed in this cell group. Prolonged stimulation of the medial preoptic area led to a biphasic response, as shown by a decrease in intensity between 30 and 60 min of stimulation.3. The increase in fluorescence intensity caused by stimulation of the arcuate nucleus was completely prevented by pre-treatment with the tyrosine hydroxylase inhibitor alpha-methyl-tyrosine. Thus, the effect appears to be due to an enhancement of amine synthesis.4. The intensity values found after synthesis inhibition were used for a preliminary estimation of the catecholamine turnover time in the nerve cell bodies of the arcuate nucleus.5. In conclusion, electrical stimulation appears to induce a characteristic type of concentration change in the nerve cell body, at least under certain experimental conditions. It is compared with similar responses to physiological changes such as the reaction to acute cold exposure.


Neonatal infections caused by group B streptococci. Relation between the occurrence in the vaginal flora of term pregnant women and infection in the newborn infant.


A fatal human case of Pasteurella multocide septicaemia after cat bite.


Analytical scanning isoelectrofocusing. 5. Separation of glycinin subunits in urea-dithiothreitol media.


Mass spectrometry of 1-dimethylaminonaphthalene-5-sulfonyl amino acids.


Characterization of radioactive immunochemically precipitated protein antigens using SDS-polyacrylamide gels.


A convenient method for lipoxygenase isoenzyme determination.


Genetic analysis with human-mouse hybrid cells.


Insertion of small pieces of foreign genetic material into somatic cells.


Chromosome behaviour in human-mouse somatic-cell hybrids.


The identification of human chromosomes by fluorescence technics.


Somatic hybridization as a tool for the study of differentiation: a review.


Methylation of pseudorabies-virus deoxyribonucleic acid.


The effect of pseudorabies-virus infection on cellular deoxyribonucleic acid.


An unusual deoxyribonucleic acid species of mammalian cells.


Separation of bovine alpha- and beta-trypsin by affinity chromatography.


Initiation of deoxyribonucleic acid replication in mammary-gland organ cultures.


The kinetics of hydrolysis of synthetic substrates by bovine factor Xa.


Dissociation of ribosomes from oocytes of Xenopus laevis into active subparticles. Ribosomes from oocytes of Xenopus laevis possess low endogenous activity in vivo and in vitro, yet are readily stimulated by poly(U). The ease with which these ribosomes dissociate into active subparticles under conditions where polyribosomes and active monoribosomes are stable supports the view that the majority are unprogrammed.


Haematology of the Japanese quail (Coturnix coturnix japonica).


Coccidia of Rocky Mountain bighorn sheep in Western Canada.


Studies on the incidence of gastrointestinal helminths of cattle in Quebec.


Effects of methallibure (ICI 33828) on histological characteristics of the vaginal epithelium of gilts.


A proposal for large animal practice in the seventies.


Occupational health problems in agricultural workers.


Estrogen conditioning and progesterone facilitation of lordosis in guinea pigs.


Consummatory behavior during tolerance to and withdrawal from chronic depression of cholinesterase activity.


Stimulus control of cannibalism and maternal behavior in anosmic mice.


Effects of mounts without intromission upon the behavior of female rats during the onset of estrogen-induced heat.


An inexpensive, programmable, electromechanical commutator.


Effects of screening programmes on laboratory organization.


Puerperal and premenstrual depression.

Puerperal and premenstrual depression.


Effect of processing on availability of iron salts in liquid infant formula products. Experimental soy isolate formulas.


Dieldrin residues in bacon cooked by two methods.


Influence of progesterone and number of corpora lutea on ovaries in sheep.


Experimentally induced coliform (Aerobacter aerogenes) mastitis in normal cows and in cows made neutropenic by an equine anti-bovine leukocyte serum.


Critical tests of butonate as an ascaricide and boticide in horses.


Fluorometric determination of vitamin A in human blood and liver.


The inhibition of pyruvate decarboxylation in rat brain by  -ketoisocaproic acid.


Mechanism of bilirubin toxicity on tissue culture cells: factors that affect toxicity, reversibility by albumin, and comparison with other respiratory poisons and surfactants.


Rat-bite fever.

Rat-bite fever.


Compensatory hypertrophy after unilateral ovariectomy and destruction of follicles in the anestrous ewe.


Bradykinin inhibition by serum from animals subjected to thermal injury.


The acute effect of alcohol on hepatic coenzyme A and acetyl CoA concentrations.


Effect of reserpine on plasma LH levels in ovariectomized and cycling proestrus rats.


The role of renal metabolism of free amino acids in achieving the external form of the kidney.


Hydatid disease in California. Study of hospital records, 1960 through 1969.


Scanning and transmission electronmicroscopy of Schistosoma mansoni eggs, cercariae, and adults.


Ecologic studies of Venezuelan encephalitis virus in southeastern México. V. Infection of domestic animals other than equines.


Synthesis and enzymic hydroxylation of protocollagen model peptide containing a hydroxyproline residue. 1. Two protocollagen model peptides, Z-Gly-Pro-Hyp-Gly-(Pro-Pro-Gly)(5) (Z, benzyloxycarbonyl) and AOC-(Pro-Pro-Gly)(6) (AOC, tert.-pentyloxycarbonyl), were synthesized and hydroxylated with protocollagen proline hydroxylase. 2. The two model peptides were hydroxylated equally. The results suggest that the hydroxyl group of hydroxyproline contained in the N-terminal region of the peptide has no effect on the enzymic hydroxylation of the model peptide.


Case of choriocarcinoma of the lung.

Case of choriocarcinoma of the lung.


The production and assay of Myxovirus influenza A-PR8 in suspension cultures of a continuous cell line of human origin (G2).


Effect of smallpox vaccination on the tuberculin test.


Twins among the Bambara and Malinke of Mali.


Standardisation of the one-stage prothrombin time test for the control of anticoagulant therapy: the availability and use of thromboplastin reference preparations.


Morphine-withdrawal aggression: sensitization by amphetamines.


Muscimol and the uptake of  -aminobutyric acid by rat brain slices.


Rubidium-induced increase in shock-elicited aggression in rats.


Application of enzyme production properties in subtyping of group A streptococci according to T type. The production of extracellular nicotinamide adenine dinucleotide glycohydrolase (NADG) and the cell-bound lipoproteinase (serum opacity reaction, SOR) by strains of different serological types of group A streptococci, in relation to the T typing, was studied. The production of both NADG and SOR, or only one of them, was found to be characteristic of serotypes, as determined by M and T antigen. No difference in the production of these enzymes was found in relation to M-positive and M-negative variants. Investigation into NADG and SOR production as related to the T type enabled the division of a single agglutination pattern into four main groups, each of which corresponds to one specific M type or more. Of the 370 strains belonging to 12 different T-agglutination patterns, 21% produced both enzymes and 42.5% failed to produce any of them, whereas the remaining 36.5% produced only one out of the two enzymes. Five streptococcal types which did not produce NADG and SOR also failed to synthesize streptolysin S at the early logarithmic phase of growth, indicating that streptolysin S production by young cultures may be also related to serotype. No correlation was found between the production of NADG-SOR as related to serotype and the production of streptolysin O, acid phosphotase, esterase, N-acetylglucosaminidase, hyaluronidase, streptokinase, and the cell-sensitizing factor. The practical and potential usefulness of NADG and SOR production in epidemiological studies is discussed.


Indirect hemagglutination with Mycoplasma antigens: effects of pH on antigen sensitization of tanned fresh and formalinized sheep erythrocytes. An investigation of the influence of different factors affecting the sensitivity of the indirect hemagglutination test has been performed with antigens of four mycoplasmas isolated from sheep or goat. Tanned erythrocytes of sheep, fresh and formalinized, were sensitized with the above antigens. It was demonstrated that, with formalinized erythrocytes, the sensitivity was increased by 50 to 100 times when the sensitization was done at a low pH level. The pH level was unimportant for sensitizing fresh erythrocytes. The greatest sensitivity of the indirect hemagglutination test was obtained with fresh rather than formalinized erythrocytes. Three different types of antigens were used, and the most suitable antigen was found to be the supernatant fluid from an ultrasonically treated centrifuged Mycoplasma suspension.


Influence of culture media on the antistaphylococcal activity of fosfomycin. Antagonism or double zones of inhibition (or both) resulted when Staphylococcus aureus was exposed to fosfomycin in Brain Heart Infusion, tryptic/papaic digest of casein/soybean, and Mueller Hinton culture media; neither occurred with a totally defined, completely synthetic medium. The extent of antagonism was quantitated by determination of the absolute minimal inhibitory concentration of fosfomycin in each medium. By using the synthetic medium and inducers, the hexose-phosphate transport system appeared to be more important than the alpha-glycerophosphate transport system in providing ingress of fosfomycin into staphylococci.


Growth factor requirements of ruminal cellulolytic bacteria isolated from microbial populations supplied diets with or without rapidly fermentable carbohydrate. The predominant cellulolytic ruminal bacteria isolated from microbial populations supplied diets containing cellulose as an energy source and essentially devoid of amino acids or rapidly fermentable carbohydrates were shown to require branched-chain acid(s) for growth.


Acceleration by free carbamate of the spontaneous reactivation of carbamylated acetylcholinesterase.


Animal experiments.

Animal experiments.


A comparison of the effects of infant and adult retinal lesions upon visual acuity in the rabbit.


Serologic evidence of Coxiella burnetii infection in domestic animals in Delhi and surrounding areas.


Vellore virus: a recently recognized agent of the Palyam group of arboviruses.


Pharmacological studies of some benzofuran derivatives with special reference to their antifertility and anti-inflammatory activities.


The ilicicolins, antibiotics from Cylindrocladium ilicicola.


On the mode of action of yemenimycin.

On the mode of action of yemenimycin.


New species of Eimeria (Protozoa: Eimeriidae) from Malaysian squirrels.