On possible field effects of the solvent phase of succussed high dilutions.


Laboratory experience with homeopathic remedies.


Modern instrumentation for the evaluation of homeopathic drug structure.


Dielectric strength testing of homeopathic dilutions of HgCl2.


Thallium metallicum, a proving.

Thallium metallicum, a proving.


Effects of sulphur dynamizations on onions.


The effect of oral variolinum on subsequent primary vaccination.


Adrenalin, iron and the principle of least action.


Carcinoma of the thyroid--its prevalence in our area.


The homeopathic trend in modern medical thought.


Intra-abdominal complications following resection of the large bowel.


Biliburin metabolism.

Biliburin metabolism.


Post-operative infections and the proper use of antimicrobials in surgery.


The value of hysterogram in the diagnosis of hydatidiform mole. (A report of 42 cases).


Renal function assessment before and after surgery.


Code of medical ethics of the medical profession in the Philippines.


Polyps of the large bowel.

Polyps of the large bowel.


Electron microscope investigations of the modes of yolk and pigment formation in sea urchin oocytes.


X-ray pelvimetry in breech presentation.


Stereological studies on several ducts and vessels by injection method of acrylic resin. XVI. Arterial distribution of the submandibular lymph nodes in some mammals.


The intramural pouch in the duodenum of the indian elephant: a macro- and microscopic study of six cases.


Normal measurements of the palpebral fissure and the interpalpebral distance among Filipinos.


Studies on the weight of bone marrow of adult Japanese.


The normal electro-oculogram among Filipinos.


Milk and food. National and international surveillance.


Precision and sensitivity of gamma spectrometric measurements in milk.


State milk surveillance activities.

State milk surveillance activities.


Ultrastructure and relationships of ooplasmic components in tunicates.


Further investigations on the effects of chromomycin on morphogenesis of Ciona intestinalis.


Hybridization between Bufo arenarum and Leptodactylus chaquensis.


A complex between basic proteins and acid polysaccharides in sea urchin oocytes and eggs.


Free amino acids in developing stages of two crabs, Callinectes sapidus Rathbun and Rhithropanopeus harrisii (Gould).


Secretion of a mucosubstance in the cleaving egg of the sea urchin.


Membranous structures in continuity with the nuclear envelope, in neuroblasts.


Fluoride and respiration in amphibian eggs.


Basic proteins in parthenogenetically activated sea urchin eggs.


The crystal structure of the intermolecular complex 9-ethyladenine: 1-methyl-5-bromouracil.


Refinement of the structure of beta-tricaprin.


Enrichment and determination of traces of strontium in milk and other calcareous media.


Milk and food.

Milk and food.


The diagnosis of jaundice.

The diagnosis of jaundice.


Role of the obstetrician in the reduction of perinatal deaths.


The pediatrician's role in decreasing perinatal mortality.


Attributes of innovations as factors in diffusion.


Otogenic brain abscess.

Otogenic brain abscess.


A psychological model of individual participation in formal voluntary organizations: application to some Chilean data.


A note on bureaucracy and its "correlates".


A demographic and ecological analysis of the distribution of physicians in metropolitan America, 1960.


Occupational assimilation and the competitive process: a reanalysis.


Lymphosarcoma associated with leukaemia in children.


On biological survival.

On biological survival.


Pathogenesis of some new Mexican drugs.

Pathogenesis of some new Mexican drugs.


The law of similars and empiricism.

The law of similars and empiricism.


Pathological prescribing.

Pathological prescribing.


Mattresses for preventing pressure sores in geriatric patients.


Duties and status of an Infection Control Sister in the Exeter Hospital group.


Integration of child psychiatry with pediatrics: combined teaching programs.


General index to homeopathic remedies in the Materia Medica in English, 1825-1963.


Management of functional constipation.

Management of functional constipation.


The homeopathic trend in modern medical thought.


Repertory of foot-sweat.

Repertory of foot-sweat.


Metals for healing.

Metals for healing.


"When the indicated remedy fails...".

"When the indicated remedy fails...".


Five remedies useful in pediatric practice.


Cow's milk allergy--relieved by wet nursing: a case report.


[On the length of fingers of the inhabitants of Amakusashimoshima, Higo].


On the sole-prints of the inhabitants of Misumi, Uto-gun, Higo.


Electron microscopic on cholinesterase at the neuromuscular junction.


Milk intolerance in clinical practice.

Milk intolerance in clinical practice.


Milk and food.

Milk and food.


National and international milk surveillance.


State milk surveillance activities.

State milk surveillance activities.


Advice on medical accuracy in the entertainment media.


Communication in cross-cultural medical practice.


Removal of tonsils and adenoids: myths and bonuses.


Conductive hearing loss and its correction.


Use of erythromycin-sulfas in office practice.


A prescription for that all tired out feeling.


Definitive treatment for tumors of the eyelids .


An injectable corticoid for resistant dermatoses.


Biosynthesis of citric acid. 3. Dynamic role of metal ions in the production of citric acid by Aspergillus niger.


Synthesis of molecular associations with the properties of biological order.


Biosynthesis of citric acid. IV. The influence of mineral nutrients on the microbial production of citric acid.


The antimicrobial activity of benzothiazole basic ethers and related compounds. Some structure-activity relationships.


The antitumoral properties of 1-benzyl-3-acetyl-pyridinium chloride.


Pharmacological research on benzydamine-a new analgesic-anti-inflammatory drug.


On the metabolism of fat-soluble vitamin A and carotene during anabolism induced by methandienone, methenolone-acetate, norethandrolone, and nandrolone.


Effect of benzquinamide on conditioned avoidance response and brain monoamine levels in the cat.


Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data?


Polypeptide and kinin forming activity of deproteinised calf blood extract.


Cellular and subcellular changes in intestinal and renal tubule epithelial cells induced by sodium salicylate.


Antispasmodic agents: esters of naphthylacetic acids with N,N'-di-(2-hydroxyethyl)-piperazine.


Stability studies of antibiotics in ointments.


The pharmacological properties of melitracen (N 7001) and litracen (N 7049).


Comprehensive index for physiological functions in longitudinal studies.


Chemical and physicochemical properties of the pregna-1,4-diene-3,20-dione-11(beta),17(alpha)-triol-21-stearoylglycolate.


Research on the metabolism of pregna-1,4-diene-3,20-dione-11(beta),17(alpha)-21-triol-21-stearoylglycolate. 1. Blood levels in man.


Psilocybin reactivity and time contraction as measured by psychomotor performance.


Pharmacological activity of pregna-1,4-diene-3,20-dione-11 (beta),17(alpha)-21-triol-21-stearoylglycolate.


Structure-activity relationships in antispasmodic compounds chemically related to N,N'-Di-[alpha-(1-naphthyl)-propionyloxy-2-ethyl]-piperazine (Nafiverine).


Note on the statistical determination of dietectic preferencies of insects.


Immunity against the different stages of malaria parasites.


Some aspects of the pathogenesis of malaria.


Patterns of immunity and resistance in rodent malaria infections.


Further investigations on resistance and immunity in mice against an infection with Plasmodium berghei.


Poisoning from ingestion of asthma "powders".


Malaria ovale; some clinical and serological observations.


The pathogenesis of hexadimethrine necrosis of the pituitary and adrenal.


Potential anticancer agents V. Synthesis of folic acid and pteroic acid analogs derived of caffeine and theophylline.


Novel polycyclic heterocycles. 3. Derivatives of 10,11-dihydrodibenzo[b,f][1,4]thiazepine.


Studies on gelatin as a blood substitute.


Automated analysis in nutritional research.


Alterations in fine structure of collagen in amyloidosis.


Synthesis and pharmacological properties of acylphenol-ethers.


Pharmacological study of 3-(p-Propionyl-o-methoxy-phenoxy)-1,2-propanediol.


Tolerance indices of some-beta-phenoxyethylamino derivatives with local anaesthetic properties.


Morphologic quantification of muscular lesions after injections of aqueous solutions.


A method elaborated for the measurement of small volumes and its application for the evaluation of antiphlogistic effects.


Serum thyrotropin activity in pregnancy.


Cardio vascular responses and antifibrillatory action of some newly synthesized lignocaine analogues.


Studies on the denaturation of biological macromolecules by chemical carcinogens. I. Aggregation, viscosity and optical rotation changes produced in ovalbumin by nitrosamines and other water-soluble carcinogens.


The effect of beta-mimetic adrenergic drugs on the activity of the pregnant human uterus, tested with the intra-uterine pressure method.


Ethionamide blood levels after administration of the drug under various pharmaceutical forms.


The otosclerotic syndrome.

The otosclerotic syndrome.


Knuckle pads and similar-looking disorders.


Electron microscopic studies of oral lichen planus.


Pemphigus: autopsy findings in fifty five cases.


On the origin of the nevus cells.

On the origin of the nevus cells.


Purpura anularis teleangectodes and pellagra in Japan.


On porokeratosis-Mibelli or keratosis excentrica.


A study on some fungi infested by acaroid mites.


Studies on the metabolism of Melitracen (N 7001) in rats.


Some pharmacological actions of acenocoumarin.


On the in vivo kinetics of drug action.

On the in vivo kinetics of drug action.


Synthesis and CNS-pharmacological properties of a new phenoxyalkanolamines serums.


Histological investigation of the effect of storage on dog kidney tissue.


Tape stripping in dermatological research. A review with emphasis on epidermal biology.


A method for recording the vascular responses to pre- and postganglionic sympathetic nerve stimulation in the same preparation in the dog.


Studies on kaolin-treated human plasma and room-temperature stored human plasma.


Degenerative phenomena in the developing muscle tissue.


Experimental study of intracranial pressure. IV. Brain displacements.


Effect of the colchicine on the skeletal muscle during development.


Histochemical studies of corpora amylacea in the human central nervous system.


Hormones and their influence in epilepsy.


Persistent trigeminal artery. A case associated with multiple bilateral aneurisms.


Electrophysiological studies of hippocampal epileptiform discharges during emotional stages.


Gamma-aminobutyric acid as a modulator of central nervous system activity.


Development of cortical visual evoked responses in the albino rat.


Study of the toxicity of isoxyl. Research on the pathological effects of isoxyl in the rat undergoing chronic experimentation.


Smooth-muscle relaxant activities of some new beta-phenoxyethylamines.


Production of encephalomalacia in chicks with diets containing vegetable oils.


Lumbar discography. A myelographic correlation.


Ortho-substituted beta-phenoxyethylamino derivatives. New local anaesthetic drugs.


New coumarin derivatives with saluretic and choleretic activity.


Studies on the denaturation of biological macromolecules by chemical carcinogens.


Blood levels after administration of 7-chloro-13-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepine-2-one (diazepam) in various forms.


Cardiovascular and other pharmacologic activities of three beta-phenoxyethylamines with local-anesthetic activity.


The effect of alkyl substitution in drugs. XVI. Basic ethers of 10,11-dihydro-5h-dibenzo[a,d]cyclohepten-5-ol and some related compounds.


Studies on the absorption and elimination of benzydamine in the mouse, rat, dog, and man.


Effect of magnesium asparaginate on the coronary circulation.


Effect of magnesium asparaginate on glucose and fat metabolism.


Difference in action between D- and L-potassium and magnesium aspartates.


Blood alcohol levels and psychotropic drugs.


Influence of parenterally administered tri-hydroxyethyl-rutoside upon capillary resistance.


2-arylcyclobutylamines and -amino acids.


The effect of alkyl substitution in drugs. XVII. Synthesis and pharmacological properties of alkyl-substituted benzhydryl derivatives of piperazine.


Electronic computers in medical education of the future.


Mechanisms of intestinal absorption as they relate to quaternary ammonium compounds.


Some remarks on the interaction of macromolecules with other molecules and ions.


Noise an occupational hazard and public nuisance.


An experiment in education for family practice.


Obesity and the evolution of man.

Obesity and the evolution of man.


Serum electrolyte relationship to electrocardiographic change in exercising athletes.


Anterior communicating aneurysms. A rebuttal.


What is wrong with fee splitting?

What is wrong with fee splitting?


Laboratory procedures: their clinical significance. Urinalysis.


The doctor's dilemma.

The doctor's dilemma.


Neonatal jaundice.

Neonatal jaundice.


The uses of medical journals.

The uses of medical journals.


The murky ambience.

The murky ambience.


Coexistent nontoxic lingual and median-cervical ectopic thyroid. Surgical management.


Computers and blood bank control.

Computers and blood bank control.


Intrauterine fetal transfusion. An unusual occurrence.


Polio vaccines--live or inactivated?

Polio vaccines--live or inactivated?


Mesenteric panniculitis.

Mesenteric panniculitis.


Mortality from myocardial infarction in Roseto.


Use of a pump oxygenator in clinical cardiac failure.


Treatment of tennis elbow. Use of a special brace.


Prognostic judgments of gastroenterologists, medical students, and college undergraduates. A comparison of reliability in cases of Laennec's cirrhosis.


Municipal drinking water and cardiovascular death rates.


Arteriosclerotic heart disease in Roseto, Pennsylvania.


Coronary heart disease in the Western collaborative group study. A follow-up experience of two years.


Therapeutic abortion law confusion.

Therapeutic abortion law confusion.


Law and medicine. Problems of school team physicians.


Investigations on the determination of bilateral symmetry in the fish, Lebistes reticulatus.


The effects of homopolyribonucleotides on the development of ascidian eggs.


Changes in the ultrastructure of amphibian eggs following fertilization.


Xanthine oxidase (dehydrogenase) activity during chick development.


Cell and hemoglobin differentiation in explants of the area vasculosa in the chick embryo.


Nuclear transplantations between two  subspecies of Xenopus laevis, (Xenopus laevis laevis and Xenopus laevis petersi).


Homospecific and heterospecific triploids of Bufo vulgaris and Bufo viridis.


Purification and partial characterization of alanine oxoglutarate transaminase (AOT) from resting cottonseeds.


Classical conditioning. I. Its utilization in producing abnormal breathing in sheep.


The temporal stability of chains of word associations.


Mentalism revisited.

Mentalism revisited.


Tuberculin test as a control in tuberculosis.


Poor visual results following retinal reattachment.


The effect of antioxidants on the quality of pork.


The interrelationship of hematogenous and lymphatic tumor cell dissemination: an experimental study.


Influence of calcium ions on growth and nitrogen fixation in cultures of the nitrogen fixing microorganism no 121-I at pH values 6.5, 7.0 and 7.5.


Studies on the metabolism of the nuclides of Ca and Sr in mammals. I. Retention of 85Sr in the rat.


Intracellular distribution of liver deoxyribose-5-phosphate aldolase.


The purification and properties of ALA dehydratase from human erythrocytes.


The biochemical constituents of horse embryonic gonads.


On the structural modification of phosvitin by alkali.


Effect of ethionine on urea synthesis in rat liver.


A program of bowel training.

A program of bowel training.


Intestinal obstruction in spinal cord injury patients.


The acute abdomen in spinal cord injury patients.


How paraplegic veterans help others.

How paraplegic veterans help others.


Function and organization of the first Swiss university paraplegic centre.


Incidence of vesicoureteral reflux in paraplegia as related to the level of injury and the type of urinary drainage.


Preliminary observations of the regeneaative potentials of the spinal cord aftet cryogenic surgery.


Renal function in patients with spinal cord injuries.


The management of the spastic contracted bladder in spinal cord dysfunction.


Experimental chronic hydronephrosis in dogs.


Development of a servo controlled tiltboard using heart rate or blood pressure as feedback controllers.


A specially adapted mobile standing device (surfboard) for spinal cord injury patients.


Vasoresection following epididymitis among patients with spinal cord injury.


Anterolateral operations in cervical spinal fractures report of a series of 39 cases.


Contrast material in the upper urinary tract following delayed retrograde cystography.


Further evidence for physiologic ureteral innervation.


Spinal deformity in paraplegia.

Spinal deformity in paraplegia.


The Bischof myelotomy for treatment of spasticity in paraplegics.


Posterior dislocation of the L4 body accompanied by massive extrusion of the disc above and below.


A new wheel chair brake.

A new wheel chair brake.


Management and evacuation of Vietnam casualties.


Preliminary observations on the effect of oral zinc sulfate on the healing of decubitus ulcers.


A new bucket seat for the prevention of pressure ulcers.


Low pressure hyperbaric oxygen treatment of decubiti and skin ulcers.


Intermittent catheterization in paraplegic patients.


Transfer of the brachioradialis to enhance wrist extension in spinal cord injury.


A radium accident in a hospital.

A radium accident in a hospital.


High energy roentgen ray contamination of the electron beam from a medical betatron.


The genetically significant dose from roentgen examinations in Finland in 1963.


Radiopharmaceuticals.

Radiopharmaceuticals.


Radiation protection dosimetry at the 1.2 GeV electron synchrotron at the University of Lund.


An emergency food monitor.

An emergency food monitor.


Measurements of the light yielded by fluorescent screens.


Tests on the collecting efficiency of charchoal-filters for monitoring of airborne radioiodine.


90 Sr and  137 Cs in surface and drinking water in Finland.


Leucocyte counts in normal and irradiated persons.


The  90 Sr content of human bone and  137 Cs content of human muscle in Finland 1963-1965.


The dose dependence of mutation rates in the rad range, in the light of experiments with higher plants.


Radiation-induced effects of mouse foetuses. A preliminary report.


Radiation induced cataracts after radium therapy in children. A preliminary report.


Radiation-induced chromosome aberrations in occupationally exposed persons.


The molecular basis of differentiation in early development of amphibian embryos.


Optimizing reproduction in a randomly varying environment.


The moulding of senescence by natural selection.


A modification of Wigglesworth's model for the excretion of uric acid in insects, in the light of modern hypotheses of ion transport.


Insect antennal development and the serrate gene in Tribolium castaneum.


Statistical dependency between intervals in neuronal impulse sequences.


A note on orientation in mitosis and meiosis.


On experimental selection for super-hibernating and non-hibernating lines of Syrian hamsters.


The quaternary and fibrillar structure of native collagen.


A theoretical study of the role of salt concentration in the melting of DNA.


The determination of the intercellular bridge resistance between smooth muscle cells.


Theory of use of the turnover rates of body water for measuring energy and material balance.


Peripheral arterial disease.

Peripheral arterial disease.


Natural history and clinical background of cerebrovascular disease.


Karyotype, meiosis and spermatogenesis in a sample of men attending an infertility clinic.


Immunotolerance to simple chemicals. Hypersensitivity to simple chemicals as a model for the study of immunological tolerance.


Some retrospective studies of cerebrovascular disease.


Workshop on the epidemiology of cerebrovascular disease.


Prospective epidemiologic studies of cerebrovascular disease.


Sociological approach to the epidemiology of cerebrovascular disease.


Cerebrovascular disease epidemiology: a workshop. Introduction.


Cerebrovascular diseases: natural history.


Fallout  137 Cs in fish and plancton from lake Mälar and the Baltic.


Relations between  90 Sr levels in the Danish environment.


Gammaspectrometric determinations of  137 Cs in Finnish milk.


Caesium-137 and strontium-90 in air, precipitation, soil and agricultural products in Norway.


Impact of cerebral palsy on patient and family.


Editorial: wanted--a revised Income Tax Act that recognizes the role of married women in the labor force.


Intensive care unit in cardiovascular surgery.


Varicose veins of the lower limbs.

Varicose veins of the lower limbs.


Nursing care in varicose vein surgery.

Nursing care in varicose vein surgery.


Project bed rest.

Project bed rest.


Continuing pharmaceutical education.

Continuing pharmaceutical education.


Evaluation of continuing education programs.


Northeastern University investigates programmed instruction.


Practical approach to continuing education.


Spotlight on learning.

Spotlight on learning.


Continuing education programs by the pharmacist.


Do you know your professional fee?

Do you know your professional fee?


The community pharmacist and...penicillin allergy.


The use of the electroencephalogram in the evaluation of head trauma.


Survey of most frequently named products in ingestion accidents.


Weekly clinicopathological exercises.

Weekly clinicopathological exercises.


Lupus nephritis. Renal function after prolonged survival.


New metabolizable immunologic adjuvant for human use. 5. Evaluation of highly purified influenza-virus vaccine in adjuvant 65.


Intermittent branched-chain ketonuria. Variant of maple-syrup-urine disease.


Present-day requirements for state hospitals joining the community.


Radiocarbon dating and archeology in North America. The history of the development of a radiocarbon chronology shows how the establishment of the times of events and the order of them has greatly improved the understanding of prehistory in North America. This is true also of other parts of the world. Too little has been said of existing discordance between archeologically determined sequences, and interregional associations, and the radiocarbon chronology. It does appear that these will be resolved as additional dates are added and as the results become more finely calibrated so that secular variations may be accounted for. The collaborative aspect of the venture was apparent at the outset. Nevertheless no one expects an archeologist to delve into nuclear physics and geochemistry, and vice versa. There is great need, nevertheless, for the man in the laboratory to comprehend the difficulties of sample collecting and of judgement of the significance of the source of organic matter to be dated. At the same time, the archeologist must become more familiar with the importance of the various steps in the processing of the sample and with, what is most vital, interpretation of the significance of the numbers that appear on the counters.


Radiant solar energy and the function of black homeotherm pigmentation: an hypothesis. White zebra finches exposed to artificial sunlight used an average of 22.9 percent less energy after they were dyed black. The hypothesis that black homeotherm coloration functions primarily to maximize absorption of radiant solar energy is suggested. This hypothesis may explain the dark skin pigmentation of certain human populations.


Tyrosinase inhibition: its role in suntanning and in albinism. Tyrosinase inhibitor (molecular weight less than 5000; extracted from various melanomas) fully inhibits soluble tyrosinase but only partially inhibits tyrosinase "aggregated" into melanosomes; the inhibitor can be inactivated by ultraviolet light. S91 Albinotyrosinase Type B apparently cannot "aggregate" into melanosomes because its protein carrier is genetically altered. Therefore, albinotyrosinase remains vulnerable to its inhibitor and cannot produce melanin, even though the enzyme has a functioning active center.


Transfer following operant conditioning in the curarized dog. Dogs were trained to press a pedal to avoid shock. They were then operantly reinforced for making or for refraining from making a series of electromyographic responses while almost completely curarized. Tests after recovery from curarization showed that operant conditioning under curare influenced the original pedal-press response.


Hexokinase isoenzymes in liver and adipose tissue of man and dog. A hexokinase, with a low Michaelis constant, not previously described, has been found in extracts of human and dog liver but not of rat liver. Earlier reports are contradicted in that glucokinase occurs in extracts of liver from well-nourished humans and dogs; it is absent, or almost so, during states of poor nutrition.


Abductin: a rubber-like protein from the internal triangular hinge ligament of pecten. The rubber-like internal triangular hinge ligament from Pecten was studied by light and electron microscopy, x-ray diffraction, and chemical analysis. The ligament is composed of an amorphous protein, abductin. In physical properties abductin is similar to elastin and resilin but distinct by amino acid analysis. It is characterized by high concentrations of glycine and methionine.


Transmission and passage of experimenal "kuru" to chimpanzees.


Tryptophan hydroxylation: measurement in pineal gland, brainstem, and carcinoid tumor. Development of a rapid and sensitive radioassay has permitted study of the conversion of tryptophan to 5-hydroxytryptophan in mammalian tissues. Of normal tissues examined, beef and rat pineal gland contained the highest activity. This is the first direct demonstration of tryptophan hydroxylase in this hydroxyindole-rich tissue. Rat and rabbit brainstem and human carcinoid tumor also had quantities of enzyme that could be measured easily. The reaction requires a reduced pteridine and oxygen and is inhibired by Para-Chorophenylalanine.


Association of illness with prior ingestion of novel foods. Rats were permitted to ingest a novel food and a familiar food. One hour later they were x-irradiated. When they were subsequently allowed to choose between these foods, their preference for the novel food was less than that exhibited by appropriate controls.


Visual pathway mediating pineal response to environmental light. Activity of the melatoninforming enzyme, hydroxyindole-O-methyltransferase, in rat pineal is increased when the animal is exposed to continuous darkness, and it is decreased by exposure to continuous light. Response to environmental light is initiated in the retina and transmitted to the pineal by way of the central nervous system and the cervical sympathetics. The central visual pathway essential for mediation of this response is the inferior accessory optic tract. Visual pathways to thalamus and tectum do not participate in this response.


Averaged neural electrical activity and arousal. Multiple-unit activity from many brain sites of the unrestrained cat was recorded by means of an averaging technique during all phases of sleep and waking. All thalamic and medial reticular sites showed activity levels closely correlated with the animal's observed behavior even under conditions when the electroencephalogram appeared dissociated from behavior.


Cytogenetical and clinical investigations in four subjects with anomalies of sexual development.


The frequency of iris bicolor (segmentary heterochromia) in a school population.


Habilitation of thalidomide children: the nursing approach.


Effectiveness of nursing visits to primigravida mothers.


Coccygodynia among the geriatric population.


Further observations on the need for a National Scientific R & D Budget.


Cardiac changes related to phenothiazine therapy, with special reference to thioridazine.


Results of cryothalamectomy for parkinsonism in patients over 70.


Effects of thioridazine on chronically regressed patients.


Sulfhydryl inhibitors for clinical cancer chemotherapy.


Drug therapy with or without group discussion: effects of various regimens on the behavior of geriatric patients in a mental hospital.


Anorexigenic drugs in perspective.

Anorexigenic drugs in perspective.


Unilateral osteoporosis in longstanding hemiplegia in the elderly.


Is the nursing home the mental hospital's back ward in the community?


Some characteristics of a group of senior citizen volunteers for physiological studies.


Cardiopulmonary resuscitation: review of one year's experience in a general hospital.


Psychological reactions in fatal illness. I. The prospect of impending death.


Fever associated with juvenile rheumatoid arthritis.


Hereditary hemolytic anemia with hexokinase deficiency. Role of hexokinase in erythrocyte aging.


Clinical implications of extragonadal estrogen production.


New concepts of residential care for the mentally retarded.


Jenner's "Evergreen Valley".

Jenner's "Evergreen Valley".


Court clinics in Massachusetts.

Court clinics in Massachusetts.


Case records of the Massachusetts General Hospital. Case 1-1967.


Childhood migraine.

Childhood migraine.


Electrophysiologic studies during scanning and passive eye movements in humans. It has been demonstrated in man that mechanically induced shifts of the retinal image without change in total luminous flux evoke a parietooccipital electrical response (lambda waves). The technique provides a simple method of quantifying responses in the visual system without complication by voluntary movemnents and their associated readiness potentials. The observation contradicts the view that lambda waves are directly concerned with mechanisms preventing blur duiring eye movement.


Evoked pressure responses in the rabbit eye. In the rabbit, a sensory stimulus of low intensity evokes a characteristic transient intraocular rise in pressure with an amplitude as great as 10 millimeters of mercury. This alpha- adrenergically mediated phenomenon occurs concomitantly with a general arousal response and appears to be caused by contraction of the orbital smooth muscle of Müller.


Temporary abolition of pain in man.

Temporary abolition of pain in man. In eight patients with intense chronic cutaneous pain, sensory nerves or roots. supplying the painful area were stimulated. Square-wave 0.1-millisecond pulses at 100 cycles per second were applied, and the voltage was raised until the patient reported tingling in the area. During this stimulation, pressure on previously sensitive areas failed to evoke pain. Four patients, who had diseases of their peripheral nerves, experienced relief of their pain for more than half an hour after stimulation for 2 minutes.


Ethical issues in research with human subjects. It is obvious that many disciplines confront ethical problems in research in which situational details may vary, but in which the same ethical principles may prevail. I write not in order to propose a definitive set of rules but to demonstrate how situations posing ethical problems can be reduced and more readily resolved by rational analysis of underlying issues and principles; I hope to stimulate further analysis and dialogue. It might be particularly helpful if researchers in a wide range of disciplines contributed experiences permitting a sharpening of guidelines. Finally, it is conceivable that a code of ethics might eventually be promulgated by a supradisciplinary body such as the AAAS, and that such a code could then be adapted and adopted by other scientific bodies and professional organizations-even by specific agencies such as research institutes, clinics, institutions, and schools.


Pahutoxin: a fish poison.

Pahutoxin: a fish poison.


Leukocyte mitosis: suppression in vitro associated with acute infectious hepatitis. Inhibition of mitosis in vitro was observed in leukocytes from patients with acute infectious hepatitis. Similarly, in cultures of normal leukocytes, after the addition of small amounts of serum from patients with hepatitis, mitosis was suppressed. Althoutgh the incidence of mitosis became normal in leukocytes from convalescent patients, there were chromosomal abnormalities.


Bacterial growth rate in the sea: direct analysis by thymidine autoradiography. Autoradiography with tritiated thymidine was used to study microbial growth directly in nature. The epiphyte Leucothrix mucor was used since it is a large filamentous bacterium with a characteristic morphology making it recognizable in natural collections. The technique was developed initially with pure cultures. The relation between growth rate and the rate of accumulation of radioactive cells permitted derivation of a constant for use in calculating growth rate in natural material and in two-membered cultures of L. mucor growing epiphytically on pure cultures of marine algae. The growth rate (generation time) in two-membered cultures with the red alga Antithamnion sarniense was 94 minutes under the conditions used. In nature the growth rate of a sample from Iceland was 685 minutes; that of a sample from Long Island Sound was 660 minutes. There was no evidence of preferential growth in the basal portion of bacterial filaments nearest the algal surface. However, filamentous growth in nature, but not in pure or two-membered culture, was nonrandom, growth being clustered in some regions.


Tryptophan deficiency in rabbit reticulocytes: polyribosomes during interrupted growth of hemoglobin chains. Of several amino acids essential for optimum hemoglobin synthesis by the rabbit reticulocyte, only omission of tryptophan results in polyribosome disaggregation. This disaggregation is prevented by the omission of both tryptophan and an amino acid that is relatively more essential than tryptophan for hemoglobin synthesis. Since tryptophan is located only near the amino-terminal ends of both chains of rabbit globin, the results indicate that single ribosomes and those in polyribosomes are in a dynamic state in the intact cell.


Diagnosis of gaucher's disease and niemann-pick disease with small samples of venous blood. Enzymes which catalyze the hydrolysis of glucocerebroside and sphingomyelin have been demonstrated in preparations of washed human white blood cells. The level of activity of these respective enzymes is markedly decreased in leukocyte preparations obtained from patients with Gaucher's and Niemann-Pick diseases. Assay of these enzymes may be useful in the differential diagnosis of the sphingolipidoses.


Erythrocyte chimerism after injection of spleen cells into anemic mice of the W-series. Anemic mice (W(v)W(v)) when injected at birth with a mixture of isologous (genotype W(v)w) and homologous spleen cells, showed an improvement in their peripheral blood picture when adult. Red blood counts, red cell size, and electrophoresis of the hemoglobins indicated that, in some cases, the homologous tissue had become implanted and, in others, the isologous tissue was functioning.


Biosynthesis of DNA by isolated mitochondria: incorporation of thymidine triphosphate-2-C-14. Thymidine triphosphate-2-C(14) and other deoxynucleoside triphosphates are incorporated into the DNA of isolated mitochondria from rat liver cells. The reaction is partially dependent on the other deoxynucleoside triphosphates and proceeds in the virtual absence of bacteria. The product has the properties of mitochondrial rather than nuclear DNA, and end-group studies indicate labeling of the interior of the molecule.


Negro variant of glucose-6-phosphate dehydrogenase deficiency (A-) in man. Glucose-6-phosphate dehydrogenase in erythrocytes of the Negro type associated with enzyme deficiency (A(-)) was separated by chromatography on a carboxymethyl-Sephadex column from the electrophoretically indistinguishable Negro variant with normal enzyme activity (A(+)). Quantitative immunologic neutralization tests indicated that the A(-) enzyme had about the same enzymatic and serological activity as the A(+) and the normal (B(+)) enzymes. The enzyme activity of the A(-) variant in young erythrocytes was similar to that in young cells from normal individuals, although the activity of the A(-) variant in unfractionated red cells was 10 to 15 percent of normal. These data indicate that the basic defect in the variant enzyme (A(-)) is a structural mutation which causes more rapid degradation of the enzyme during erythrocyte aging.


Effects of tetrodotoxin on excitability of squid giant axons in sodium-free media. The effect of tetrodotoxin on excitability of internally perfused squid giant axons immersed in various sodium-free media was examined. Action potentials were found to be suppressed by this substance, with or without sodium ion in the external medium. Tetrodotoxin showed a strong suppressive effect upon action potentials produced in media containing salts of only divalent cations (CaCl(2), CaBr(2), SrCl(2), or BaCl(2)). Our findings concerning the action of tetrodotoxin do not support the separate-channel hypothesis for excitable membranes.


Arterial embolism.

Arterial embolism.


Hypertrophic osteoarthropathy secondary to upper-gastrointestinal-tract neoplasm. Case report and review.


The distribution and concentration of tritiated digoxin in human tissues.


Hypertrophic osteoarthropathy in portal cirrhosis.


Hypophosphatemic osteomalacia with hyperglycinuria.


Dysproteinemia of the myeloma type associated with a thymoma.


Studies on the mechanism of diuresis after relief of urinary-tract obstruction.


A new acid-base nomogram featuring hydrogen ion concentration. Henderson revisited.


The failure of hemodynamic improvement after valve replacement surgery. Etiology, diagnosis, and treatment.


Pulmonary hypertrophic osteoarthropathy.


Diabetes mellitus in man and experimental animals.


Anemia and symptoms.

Anemia and symptoms.


Polymyalgia rheumatica. A manifestation of systemic giant-cell arteritis.


Hormonal and biochemical studies in a diabetic family.


Roentogenology of the Brachmann-de Lange syndrome.


Factors producing spurious obstruction of the inferior vena cava in infants and children with abdominal tumors.


Radiologic and clinical evaluation of pheochromocytoma in children: report of 6 cases.


Isosensitive radioisotope scanning.

Isosensitive radioisotope scanning.


Simultaneous performance of isosensitive scanning and bilaminoscanning.


What is a biomedical computer center?

What is a biomedical computer center?


Medical records and computers.

Medical records and computers.


Roentgen visualization of uterine artery calcification.


Cystic lymphangioma of the breast. First roentgen description.


Computers in biomathematical applications.


General principles of computer systems.

General principles of computer systems.


The evaluation of metastatic thyroid carcinoma with technetium-99m pertechnetate.


Regional abnormalities in pulmonary arterial blood flow during acute asthmatic attacks.


Angiography in inflammatory space-occupying lesions of the kidney.


Use of computers in pharmacokinetics.

Use of computers in pharmacokinetics.


Computers in public health.

Computers in public health.


Use of small sealed sources in radiotherapy.


Selective angiography of the inferior phrenic arteries.


Angiographic diagnosis of an anomalous right coronary artery arising from the pulmonary artery.


Transjugular percutaneous cholangiography.


Angiographic and scintillographic identification of Riedel's lobe of the liver.


Computers in physiological analysis and simulation.


Hepatic angle in roentgen evaluation of peritoneal fluid.


Vertebral artery reflux: a laboratory investigation of the nonobstructive causes of retrograde flow of contrast material in the contralateral vertebral artery.


Pseudo-subdural hematoma.

Pseudo-subdural hematoma.


Cerebrovascular occlusive disease as a differential diagnosis in subdural hematomas.


The Cornelia de Lange syndrome: radiographic findings.


Impact of congenital heart disease on the family: preliminary report.


Angiography in renal and perirenal inflammatory masses. Report of three cases.


Conservative surgery for bleeding peptic ulcer.


Criminal behaviour AND THE Y chromosome.


Residency education.

Residency education.


Mastership in clinical biochemistry.

Mastership in clinical biochemistry.


Lobar pneumonia in Africa.

Lobar pneumonia in Africa.


Risk of congenital dislocated hip.

Risk of congenital dislocated hip.


Neurological disease in Carlisle.

Neurological disease in Carlisle.


"Cardiovascular Research".

"Cardiovascular Research".


Effect of atrial systole on right ventricular stroke output in complete heart block.


Survey of mental illness in adolescence.


Immunoradioactive agent against cancer.

Immunoradioactive agent against cancer.


Standardization of the one-stage prothrombin time for the control of anticoagulant therapy.


Normal cerebral function with bilateral carotid occlusion.


Trimipramine.

Trimipramine.


New wards for old.

New wards for old.


Rheumatic fever prophylaxis.

Rheumatic fever prophylaxis.


Future of clinical pharmacology.

Future of clinical pharmacology.


Virus in urine.

Virus in urine.


Puzzle of stupor.

Puzzle of stupor.


Surgery of angina pectoris.

Surgery of angina pectoris.


Staphylococcal sepsis in a new surgical ward.


Haemodynamic effects of propranolol (Inderal) in acute myocardial infarction.


Evaluation of MK-870: a new potassium-sparing diuretic.


Effect of Lyndiol, an oral contraceptive, on breast cancer.


Alternative discriminating function for determining hormone dependency of breast cancer.


Thrombosis of the pulmonary arteries and the nephrotic syndrome.


Gentamicin.

Gentamicin.


Standardized filing system in the family doctor's surgery.


Financing of students: grants or loans?

Financing of students: grants or loans?


Radiology of the colon.

Radiology of the colon.


Radiology of the stomach and the gastric camera.


Mass movements (mass peristalsis) and diverticular disease OF THE COLON.


Estimation of radiation doses to tissues after administration of tritiated corticosteroids to the rat.


A ratio-subtract device for detecting selective localisation of isotopes in clinical scintiscanning.


Radiation doses resulting from the administration of tritiated folic acid and tritiated water to the rat.


The depth of the spinal cord below the skin.


A punched-card interlock for a superficial therapy set.


Healing of intestinal anastomosis.

Healing of intestinal anastomosis.


Thyroid surgery: Vancouver General Hospital, 1959-1963.


Carotid-artery surgery for cerebrovascular insufficiency: experience with 78 procedures in 60 patients.


Atonic megacolon.

Atonic megacolon.


Reconstruction of the osteoarthritic knee by high tibial osteotomy and joint clearance.


The effects of dexamethasone, norethandrolone, promethazine and a tension-relieving procedure on collagen synthesis in healing flexor tendons as estimated by tritiated proline uptake studies.


The effect of histamine stimulation on the net ionic fluxes in Heidenhain and Pavlov fundic pouches.


Hamilton Stewart nephroplasty.

Hamilton Stewart nephroplasty.


The problem of drooling in cerebral palsy: a surgical approach.


Duodenal reflux in the genesis of acute pancreatitis.


Osteomyelitis in infancy.

Osteomyelitis in infancy.


Congenital absence of the nose: a case report.


Xanthomatous tumour of the lung: a case report and review of the literature.


The effect of interruption of the bronchial circulation and the addition of cortisone and low molecular weight dextran to blood perfusate during pulmonary perfusion in dogs.


Oral glucose tolerance test in normal children.


Comparison of intravenous glucose tolerance and intravenous tolbutamide response in ischemic cardiovascular disease.


Effects of insulin on excretion of nitrogen in normal, depancreatized, and steroid-diabetic rats.


Arterial fluorescein studies in diabetic retinopathy.


Study of familial patterns of reported diabetes. Evaluation of questionnaire data.


Specificity of the effect of insulin on permeability of frog sartorius muscles to sugar.


Light and electron microscopy of lesions in rats rendered diabetic with streptozotocin.


Triamcinolone provocative test in offspring of two diabetic parents.


Use of chlorpropamide in the treatment of diabetes in pregnancy.


Sugar intake and diabetes.

Sugar intake and diabetes.


The value of routine proctosigmoidoscopy.


How diuretics work.

How diuretics work.


Lung cancer concealed by other pathology.


Abnormal carbohydrate tolerance and diabetes in elderly persons.


Lesions of the small mesenteric arteries underlying intestinal infarction.


Cardioversion pseudofailures.

Cardioversion pseudofailures.


Isometric and isotonic exercise for geriatric patients.


Differential diagnosis of benign and malignant breast tumors.


Susceptibility to two strains of Friend leukemia virus in mice. A mutant strain of the Friend leukemia virus is described. The parental virus strain, passaged through ICR/Ha mice, shows no or very little activity by the spleen-focus assay in BALB/c mice (by comparison with highly susceptible DBA/2 and ICR/Ha mice) and produces typical Friend disease in these mice only exceptionally; susceptibility to this strain of virus is recessive in the (C57BL/6 x DBA/2) F(1). By contrast, the mutant virus strain is as active in BALB/c mice as in DBA/2 or ICR/Ha mice; susceptibility to the mutant virus strain is dominant in the (C57BL/6 x DBA/2) F(1).


Monocular and binocular aftereffects of chromatic adaptation. Supersaturated greens seen after long-wavelength adaptation depend upon contrast from the continuing afterdischarge of bleached "red" receptors in the surround, rather than merely upon inactivation from bleaching of "red" receptors in the test spot area. When test spot and bleach field coincide spatially, supersaturated greens are not seen. Since color mixing but not contrast was found binocularly, color contrast must be a retinal phenomenon.


Protein uptake in multivesicular bodies in the molt-intermolt cycle of an insect. Plant peroxidase injected into the hemocoel is taken up in granules by almost all tissues. These granules may become multivesicular bodies or isolation bodies which later breakdown. There is most uptake and breakdown at times in the molt-intermolt cycle when cells are engaged in active syntheses.


Nuclear-cytoplasmic interaction in DNA synthesis. In Amoeba proteus the transplantation of a nucleus engaged in DNA synthesis into a G(2)-phase (after DNA synthesis) cell results in inhibition of such synthesis. When the nucleus of a G(2) cell is transplanted into an S-phase (period of DNA synthesis) cell, such a nucleus may begin to synthesize DNA.


Dopamine protects mice against whole-body irradiation. Injection of dopamine before whole-body x-irradiation of mice resulted in 80 percent survivors whereas no irradiated controls survived; injection after exposure had no effect. D,L-Dihydroxyphenylalanine, the precursor of dopamine, had no effect on survival when injected either before or after irradiation.


Acetylcholinesterase: method for demonstration in amacrine cells of rabbit retina. The activity of acetylcholinesterase in the inner plexiform layer of the rabbit retina was not affected detectably by prior section of the optic nerve. After the animals were treated with diisopropyl phosphorofluoridate, acetylcholinesterase reappeared in the somata of the amacrine cells and in certain cells of the ganglion cell layer before it reappeared in the inner plexiform fibers. This confirms the normal presence of acetylcholinesterase at the former site. The possible role of acetylcholine in intraretinal transmission is considered.


Crayfish muscle fiber: ionic requirements for depolarizing synaptic  electrogenesis. Presence of sodium in the bathing medium is not essential for the electrically excitable depolarizing electrogenesis of crayfish muscle fibers, production of action potentials being dependent on calcium. The depolarizing electrogenesis of the excitatory synaptic membrane component does require sodium, however, and this ion cannot be replaced by lithium as it can in spike electrogenesis of many cells. Ionophoretic applications of glutamate, which in the presence of sodium depolarize the cell by activating the excitatory synaptic membrane, are without effect in the absence of sodium. Not only is there no depolarization, but the membrane conductance also remains unchanged. Thus, in the absence of inward movement of sodium across the synaptic membrane there is also no outward movement of potassium. Accordingly, it seems that increased conductance for potassium is not an independent process in the synaptic membrane, whereas it is independent of sodium activation in spike electrogenesis. Chloride activation is independent, however; increase in conductance and the electrogenesis of the inhibitory synaptic component are not affected by the absence of sodium. Implications of these findings regarding the structure of differently excitable membrane components are discussed.


Visual reaction times on a circle about the fovea. Reaction times to a dim photopic stimulus were measured on a circle about the fovea, 15 degrees from the line of direct vision. Large variations in reaction time were found on various half meridians and were interpreted as reflecting the distribution of retinal receptors.


Depression of circulating interferon response in Balb-c mice after urethan treatment. Urethan, when given to female Balb/c mice, impaired the capacity of these animals to produce circulating interferon. The effect appeared rapidly after a single injection of either 1 or 1.5 milligrams of urethan per gram of body weight and was of short duration. The possibility that this inhibition of the production of interferon plays a role in the enhancement of viral leukemia by urethan should now be considered.


State as a determinant of infants' heart rate response to stimulation. With each infant serving as his own control, the data indicate that waking or sleeping states, independent of the prestimulation heart rate, can significantly affect the heart rate response to tactile stimulation.


Curvature in the saccadic movement.

Curvature in the saccadic movement.


Determination of episcleral venous pressure in the eye. A comparison of three methods.


The skin: problems of inheritance.

The skin: problems of inheritance.


Retinal damage by visible light. A physiologic study.


A new system for visual axis measurements in the human eye using ultrasound.


The effects of local anesthetics upon optic nerve conduction in the cat.


Retinal hemorrhages following traumatic venous obstruction.


Visual changes associated with clomiphene citrate therapy.


Visual impairment among deaf children. Frequency and educational consequences.


Incidence of amblyopia.

Incidence of amblyopia.


The ratio of accommodative convergence to accommodation in strabismus with A- and V-patterns.


Macular function and the photostress test 1.


Eyelid tumors with reference to lesions confused with squamous cell carcinoma. 3. Keratoacanthoma.


Absence of so-called histoplasma uveitis in 134 cases of proven histoplasmosis.


Constant pressure applanation tonography with the Mackay-Marg tonometer. II. Limits of the instrument.


The water drinking test. Indications that factors other than osmotic considerations are involved.


Diabetic retinopathy and its relation to errors of refraction.


Incidence and location of melanocytomas.


Temporal lobe epilepsy. Association with homonymous hemianopsia.


The upright fundus image in indirect ophthalmoscopy.


Ring-shaped limbal tumor. Secondary to unrecognized diffuse malignant melanoma of the uvea.


Lens extraction with the hyelophake. A preliminary report.


Pseudomelanoma of the ciliary body. Report of a patient.


Cryosurgical removal of epithelial cyst of iris and anterior chamber.


Oxygen consumption of rabbit cadaver cornea.


Laser coagulation of the anterior segment. 1. Experimental laser iridotomy.


Civil emergency planning in Canada.

Civil emergency planning in Canada. THE NATIONAL OBJECTIVES OF CIVILIAN EMERGENCY PLANNING ARE: (1) protection and preservation of life and property; (2) maintenance of governmental structure; and (3) conservation of resources. The Canada Emergency Measures Organization (E.M.O.) has been developed to accomplish these objectives. E.M.O. co-ordinates other departments and agencies of federal government and its organization is reflected within provincial and municipal governments.Present E.M.O. accomplishments include: an attack warning system; an emergency broadcasting system; emergency government facilities; 400 emergency measure organizations across Canada; plans to implement general readiness; a medical stockpile; and "shadow agencies" for control of housing, food and manpower.PRESENT UNDERTAKINGS INCLUDE: a national survey of fallout shelters; the equipping of the radiation defence (RADEF); the pre-positioning of the items of the medical stockpile; and the training at the Canadian Emergency Measures College at Arnprior.


The employment of emergency medical units of the National Medical Stockpile. Canada has a good National Medical Stockpile valued at 21 million dollars and consisting of packaged emergency medical units ready for use in peacetime or wartime disaster. These units are available for release to provinces for pre-positioning in selected communities provided that certain storage conditions are met and that physicians and other key health workers are prepared to take operational charge of the equipment. The major packaged units are the Emergency Hospital with a capacity of 200 beds, the Advanced Treatment Centre with equipment to give emergency medical care to 500 casualties, the Casualty Collecting Unit with equipment to give first-aid care to 500 casualties, the Emergency Blood Depot, the Emergency Clinic and the Emergency Public Health Laboratory. In addition, training equipment, supplies and units are provided.The value of the stockpile has already been demonstrated in disasters occurring inside and outside Canada. Ten Emergency Hospitals have been shipped to South Vietnam for civilian use. A similar Emergency Hospital was flown to Yellowknife, N.W.T., within 24 hours of the destruction, by fire, of the Stanton Yellowknife Hospital in May 1966.


The dental practitioner's role in emergency health services. In a national disaster, the medical profession would lose physicians and auxiliary personnel and would need assistance. Canada's 22,000 physicians and 85,000 nurses are located for the most part in potential target areas. Survivors among Canada's 6396 dentists could supply 30% reinforcement. The dentist's training, his manual dexterity and experience acquired in the management of hemorrhage, shock, débridement, suturing, reduction and immobilization of fractures, and control of pain and infection would be valuable. Additional functions he could perform would be first-aid, including but not limited to artificial respiration, early management of chest wounds, preparation of casualties for movement, and assistance in general surgical procedures. Dentists with special training in anesthesia, oral surgery or public health could be of particular value in relieving anesthetists, surgeons, radiologists and public health officers of some of their duties. Joint training of physicians and dentists in mass casualty care could increase the efficiency of the team work in disaster and is being considered by many medical and dental faculties.


Perspectives of radioactive contamination in nuclear war. The degrees of risk associated with the medical, industrial and military employment of nuclear energy are compared. The nature of radioactive contamination of areas and of persons resulting from the explosion of nuclear weapons, particularly the relationship between the radiation exposure and the amount of physical debris, is examined.Some theoretical examples are compared quantitatively. It is concluded that the amount of radio-activity that may be carried on the contaminated person involves a minor health hazard from gamma radiation, compared to the irradiation arising from contaminated areas.


Management of the acute radiation syndrome. Classification of radiation injury on a clinical basis is useful for determining priorities of evacuation and treatment in a mass casualty situation. Victims of nuclear attack would probably also suffer traumatic and thermal injuries. Four categories of surgical injury have therefore been combined with three categories of radiation injury to yield 12 classes of patients whose disposition is described. The treatment of the acute radiation syndrome is briefly discussed and concurrent injuries from trauma and burns and their possible implications are considered.


Blast injury.

Blast injury. The shock wave generated by an explosion ("blast wave") may cause injury in any or all of the following: (1) direct impact on the tissues of variations in environmental pressure; (2) flying glass and other debris set in motion by it; (3) propulsion of the body. Injuries in the first category affect gas-containing organs (ears, lungs and intestines), and acute death is attributed to air forced into the coronary vessels via damaged pulmonary alveoli. It is estimated that overpressure sufficient to cause lung injury may occur up to five miles from a 20-megaton nuclear explosion. The greatest single hazard from blast is, however, flying glass, and serious wounding from this cause is possible up to 12 miles from an explosion of this magnitude.


The management of accidental hypothermia. Accidental general hypothermia is defined as an unintentional lowering of the body temperature in a previously conscious patient due to exposure. Even mild degrees of hypothermia may be followed by death if treatment is not instituted promptly. Hypothermic patients who are still conscious may rewarm spontaneously. They should not be left unattended and, if the facilities are available, rapid rewarming appears to be the treatment of choice. Unconscious patients who are presumed to have a lower temperature of prolonged duration may not benefit from rapid rewarming. All hypothermia victims showing signs of life are potential survivors, but even with good facilities the mortality rate may be high.


Emergency health services informational and educational programs: development and present status. The development and present status of the Emergency Health Services (EHS) national and educational programs are discussed. Instituted in 1951 for medical and dental practitioners at a military school at Camp Borden, professional civilian indoctrination was later assumed by EHS at Canadian Emergency Measures College (CEMC). The federally sponsored courses there are now specialized; provincial EHS authorities undertake general indoctrination. Courses for graduates in pharmacy and nursing are also offered at CEMC. Hospital Disaster Institutes have been held across the country since 1954; Public Health Disaster Institutes, since 1966. Schools of Hygiene include the subject in graduate programs. Some years ago, three medical faculties introduced undergraduate teaching in mass casualty care; now, encouraged by the Association of Canadian Medical Colleges, a larger number are doing so. Several faculties of Dentistry, all faculties of Pharmacy, and 132 of 177 nursing schools teach apposite aspects. Professional journals have published many articles on this subject; this, for example, is the fourth Emergency Health Services Symposium presented by The Canadian Medical Association Journal.


The self-absorption of Auger electrons and x-rays in Mn-54 sources prepared by different methods.


The estimation of thorium and uranium at the submicrogram level in bone by neutron activation.


A new scintillator for liquid scintillation counting.


Analysis of errors and accuracy of simultaneous H-3 and C-14 assay in organic substances by means of an internal gas counter.


The determination of Sr-89 in biological samples.


A rotating collimator with adjustable field sizes for the 22.5-MeV betatron.


Photosensitivity of clear Perspex dosimeters.


Osteoid osteoma of the spine. A review of the literature and report of six new cases.


Localized pigmented villonodular synovitis of the knee. Report of five cases.


Chondrosarcoma in three brothers. A pathological and genetic study.


Bone regeneration in infantile osteomyelitis. Report of a case with fourteen-year follow-up.


Tissue injury caused by wound disinfectants.


Measurement of ligamentous strength in rat knees.


The prevention of thromboembolic disease by prophylactic anticoagulation. A controlled study in elective hip surgery.


Aging: the criterion problem in diagnosis of brain dysfunction.


The biochemical changes preceding tissue death in rats.


The relationship between social involvement and feeling old among residents in homes for the aged.


The effect of RNA on learning and activity in old and young rats.


Histoenzymatic studies of vascular changes in the aorta and coronary arteries in the aged rat.


Age and sex differences in the serial production of creative conceptual responses.


Age-group comparisons for the use of mediators in paired-associate learning.


Age and disillusionment: a study of value changes associated with aging.


Plasma and urinary corticoids in young and old persons.


Age differences in retroaction.

Age differences in retroaction.


Practice of speeded response in relation to age, sex, and set.


Effect of age on dehydrogenase heterogeneity in the rat.


Empyema and survival following surgery for bronchogenic carcinoma.


Stability of graphite-benzalkonium-heparin surfaces. In vitro and in vivo studies employing tritium-labelled heparin.


Renal complications associated with valve replacement surgery.


Functional evaluation of esophageal replacement in children.


Pulmonary embolectomy. An analysis of 12 cases.


Coronary artery--right heart fistulas.

Coronary artery--right heart fistulas.


Hydrops fetalis with alpha thalassemia.

Hydrops fetalis with alpha thalassemia.


Rupture of interventricular septum following myocardial infarction.


Fusion of the ankle in denervated extremities.


Medical Grand Rounds rom the University of Alabama Medical Center.


Mediastinoscopy: a valuable diagnostic procedure for the evaluation of lesions of the mediastinum.


Diffuse malignant mesothelioma of the peritoneum.


Psychopharmacologic roulette.

Psychopharmacologic roulette.


Coronary disease--its emotional impact.

Coronary disease--its emotional impact.


Diseases of the celiac and mesenteric arteries.


Traumatic injuries to the pancreas.

Traumatic injuries to the pancreas.


Monitoring the central venous pressure.

Monitoring the central venous pressure.


Axillary dissection without mastectomy.

Axillary dissection without mastectomy.


The intralymphatic administration of radioactive isotopes for treating malignant melanoma.


The influence of rotational malpositions on intracapsular fracture of the femoral neck.


Laser therapy of melanomas.

Laser therapy of melanomas.


Treatment of late recurrent granulosa cell tumors of the ovary.


Growing indications for vagotomy in perforated peptic ulcer.


A study of various surgical scrubs by glove counts.


Factors influencing the rate of healing in tibial shaft fractures.


Histopathology of small polyps of the large intestine.


Intussusception in infants and adults.

Intussusception in infants and adults.


The therapeutic action of oral Hypaque in bowel obstruction.


Metastatic tumor to the small bowel. Three cases simulating primary malignant tumors.


Meckel's stone ileus.

Meckel's stone ileus.


Calcification in primary liver carcinoma.


Corrosive gastritis due to hydrochloric acid ingestion. report of a case.


Angiography in ulcerative colitis.

Angiography in ulcerative colitis.


Spontaneous rupture of the esophagus.

Spontaneous rupture of the esophagus.


The roentgenologic features of the columnar epithelial-lined lower esophagus.


The "captive bolus" test and the pinchcock at the diaphragm. An esophageal pump and some non-diseases of the esophagus.


Localization of parathyroid adenomas by esophageal cine-roentgenography.


The nature of the lower esophageal ring.


Granulomatous colitis. Roentgenologic appearance and course of the lesions.


Spigelian hernia containing sigmoid colon.


Idiopathic portal hypertension. Comparison with the portal hypertension of cirrhosis and extrahepatic portal vein obstruction.


Pulsus and electrical alternans due to the presence of a mitral caged ball-valve prosthesis.


Diagnosis of left superior vena cava by clinical inspection, a new physical sign.


Preserving a medical document.

Preserving a medical document.


Beta-adrenergic blockade in patients with hypertrophic obstructive cardiomyopathy.


Mind stretching.

Mind stretching.


A technique for the indirect measurement of the velocity of induced venous pulsations.


The significance of the atrial situs in the diagnosis of positional anomalies of the heart. I. Anatomic and embryologic considerations.


Depression of artificial pacemakers by extraneous impulses.


The significance of the atrial situs in the diagnosis of positional anomalies of the heart. II. An angiocardiographic study of 29 patients.


Time-normalized correlation of ventricular activation and the vectorcardiogram.


Ventricular vulnerability to paired-pulse stimulation during acute coronary occlusion.


Meningococcal pneumonia.

Meningococcal pneumonia.


Depression of erythropoiesis associated with chlorpromazine therapy.


Herbals.

Herbals.


Metastatic brain abscesses. A retrospective appraisal of 29 patients.


Carcinomatosis of the lung with pulmonary hypertension. Pathoradiologic spectrum.


Critique of indirect diastolic end point. "Muffling" vs "Last" Sound.


Inhalation of oxygen and carbon dioxide gas. Effect on composition of cerebral venous blood.


Difficulties in differentiating amebic from pyogenic liver abscess.


Clofibrate and androsterone effect on serum lipids.


New cephalosporin antibiotic--cephaloridine. Clinical and laboratory evaluation.


Thalassemia in Negroes.

Thalassemia in Negroes.


Mitral stenosis. A long term postoperative follow-up.


Primary chondrosarcoma of extraskeletal soft tissue. A case report.


The guild spirit.

The guild spirit.


Auto-immune disease in NZB and NZB-NZW F1 mice. Natural history and pathology.


Phagocytosis promoting property of thyroid autoantibody.


Sarcomatoid transformation of transplanted thyroid carcinoma. Similarity to anaplastic human thyroid carcinomas.


Aflatoxin B1. Induction of malformations.


Experimental nutritional cirrhosis in the rat. Influence of choline, vitamin E, and dietary fat on triglyceride metabolism and the development of cirrhosis and ceroid.


Effect of phytohemagglutinin on lymphocytes from patients with chronic lymphocytic leukemia.


Strangulation as a method of homicide. Study (1965-1966) in New York City.


Pathogenesis of experimental bronchiectasis in laboratory rats.


Cardiac surgery and myocardial necrosis.


Fine structural changes in rat myocardium induced by thyroxine and by magnesium deficiency.


Structure of rat lung after protracted oxygen breathing.


Atrial rhythm in ventricular tacycardia occurring during cardiac catheterization.


Significance of an atrial gallop sound in mitral regurgitation. A clue to the diagnosis of ruptured chordae tendineae.


Epicardial excitation of the ventricles in a patient with wolff-Parkinson-White syndrome ( type B).


Occlusive fibroelastosis of coronary arteries in the newborn.


Ventricular performance after angiocardiography.


The structure and dynamics of leadership.


Serum lactate dehydrogenase elevation in ambulatory cardiac patients. Evidence for chronic hemolysis.


Family therapy: some contributions to treatment and training.


The Kansas modified unit plan.

The Kansas modified unit plan.


Supervisors aid authority-shy patients.

Supervisors aid authority-shy patients.


Detecting depressions in childhood.

Detecting depressions in childhood.


An orientation group for new patients.

An orientation group for new patients.


Renal failure due to carbon tetrachloride.


Contact lenses in industry.

Contact lenses in industry.


Acute benzene poisoning.

Acute benzene poisoning.


Privacy and behavioral research. Preliminary summary of the report of the panel on privacy and behavioral research. From our examination of the relation of behavioral science research to the right to privacy, we have been led to the following conclusions. 1) While most current practices in the field pose no significant threat to the privacy of research subjects, a sufficient number of exceptions have been noted to warrant a sharp increase in attention to procedures that will assure protection of this right. The increasing scale of behavioral research is itself an additional reason for focusing attention in this area. 2) Participation by subjects must be voluntary and based on informed consent to the extent that this is consistent with the objectives of the research. It is fully consistent with the protection of privacy that, in the absence of full information, consent be based on trust in the qualified investigator and the integrity of his institution. 3) The scientist has an obligation to insure that no permanent physical or psychological harm will ensue from the research procedures, and that temporary discomfort or loss of privacy will be remedied in an appropriate way during the course of the research or at its completion. To merit trust, the scientist must design his research with a view to protecting, to the fullest extent possible, the privacy of the subjects. If intrusion on privacy proves essential to the research, he should not proceed with his proposed experiment until he and his colleagues have considered all of the relevant facts and he has determined, with support from them, that the benefits outweigh the costs. 4) The scientist has the same responsibility to protect the privacy of the individual in published reports and in research records that he has in the conduct of the research itself. 5) The primary responsibility for the use of ethical procedures must rest with the individual investigator, but government agencies that support behavioral research should satisfy themselves that the institution which employs the investigator has effectively accepted its responsibility to require that he meet proper ethical standards. 6) Legislation to assure appropriate recognition of the rights of human subjects is neither necessary nor desirable if the scientists and sponsoring institutions fully discharge their responsibilities in accommodating to the claim of privacy. Because of its relative inflexibility, legislation cannot meet the challenge of the subtle and sensitive conflict of values under consideration, nor can it aid in the wise decision making by individuals which is required to assure optimum protection of subjects, together with the fullest effectiveness of research.


Weight loss in men in space.

Weight loss in men in space. Men returning from orbital flights have lost from 2 to 6 percent of their body weights. Similar losses occur during simulated weightlessness; blood normally pooled in dependent parts returns to the circulation, increasing central blood volume and causing excretion of water which is not replaced during flight.


Serum osmolality in the coelacanth, Latimeria chalumnae: urea retention and ion regulation. Samples of blood (hemolyzed) were obtained from the renal vein, the hepatic portal vein, and the heart of a freshly thawed specimen of Latimeria chalumnae. The coelacanth uses high concentrations of urea to maintain its serum osmolality at approximately that of sea water. The mean value for the total osmolality was 1181 milliosmoles per liter. The mean values (milliequivalents per liter) were: for sodium, 181; for potassium, 51.3; for calcium, 6.9; for magnesium, 28.7; for chloride, 199; and for bicarbonate, 4.7. The mean urea concentration was 355 millimoles per liter, and the mean nonprotein nitrogen was 1343 milligrams percent. Heart blood showed significantly lower values for osmolality (921 milliosmoles per liter) and nonprotein nitrogen (1030 mg percent) and was probably less severely contaminated with products of protein breakdown. Fluid from the anterior chamber of the eye showed values of 952 milliosmole/liter; the urea value for this fluid was 303 mmole/liter, and the magnesium was 7.3 meq/liter. The magnesium value for the aqueous humor was used to correct the abnormally high concentrations in the hemolyzed serum. The high level of serum potassium also was attributed to hemolysis.


Urea and its formation in coelacanth liver. Urea occurs in liver of the coelacanth Latimeria chalumnae to the extent of about 1.7 percent by weight. It was determined quantitatively by reaction with 1-phenyl-1,2-propanedione-2-oxime (Archibald reagent) and by measurement of ammonia released upon treatment with urease. Arginase and ornithine carbamoyltransferase, enzymes instrumental in the formation of urea in typical ureotelic vertebrates, occur in homogenates of coelacanth liver. Formed in part by the ornithine-urea cycle, urea may have an osmoregulatory function in the coelacanth as it has in elasmobranchs.


Nitrate ions: Potentiation of increased permeability to sugar associated with muscle contraction. Nitrate ions potentiate twitch tension and enhance the increase in permeability to sugar which occurs in electrically stimulated frog sartorius muscles. However, the potentiating effect of nitrate ions on permeability is not dependent upon an increase in twitch tension. The possible relation of changes in permeability to alterations of the concentration of calcium ions in the cell is discussed.


Genomic exclusion: a rapid means for inducing homozygous diploid lines in Tetrahymena pyriformis, syngen 1. Genomic exclusion is an abnormal form of conjugation occurring between cells with defective micronuclei and normal cells with diploid micronuclei. The progeny are heterocaryons; each cell has an old macronucleus but a new diploid micronucleus derived from one meiotic product of the normal mate. Such cells express genes found in the old macronucleus, are sexually mature, and can be specifically selected. When inbred, they give rise to lines genetically homozygous at all known loci.


Plasma membrane: substructural changes correlated with electrical resistance and pinocytosis. Inducers of pinocytosis in amoeba cause as much as a 50-fold decrease in the electrical resistance of the plasma membrane prior to the formation of the typical tunnels and vacuoles. In this state the thickness of the electron-transparent core or lamella of the unit membrane is at least twice as thick as that of the control. The changes in structure and resistance as well as the induction of pinocytosis are dependent on the initial external concentration of calcium. These changes are rapidly reversed when the concentration of calcium in the external medium is increased.


Neoplastic transformation of rat thymic cells induced in vitro by Gross leukemia virus. Cultures of embryonal rat thymus infected initially with Gross leukemia virus have, at the present time, abundantly replicated infectious virus particles for 20 months. Cells from these cultures, after 3 months in vitro, displayed morphological changes and induced formation of tumors upon isotransplantation. The tumors were serially transplantable, and subsequent transplants continue to carry the initial Gross leukemia virus.


Poisoning with DDT: effect on reproductive performance of Artemia. Brine shrimp die within 5 days after being given doses of above 10(-5) parts of DDT per million. At this and lower doses, shrimp deposited broods at a normal frequency, and cysts predominated. The number of cysts that emerged and the survival of larvae to adulthood from broods of treated parents exceeded those from controls. Therefore lethality based on induced dominant or sex-linked recessive gene mutation was not evident. Decreased fecundity is due to maternal debility.


Activation analysis of soluble and fixed sodium in mammalian hair. Antelope hair was soaked in sodium-22 to simulate external contamination and then systematically washed to remove all traces of the sodium; progress of the wash was followed by gamma-ray spectrometry. Hair was then activated by neutron bombardment which showed sodium still present as sodium-24. It is concluded that a fraction of sodium in hair can be readily washed away with water and that a second fraction is held in the hair in such a manner that extended washing does not remove it. This suggests that sodium in two states may be associated with hair, one as an external contaminant and the other as a more nearly integral part of the hair.


Antiandrogen implanted in brain stimulates male reproductive system. Chronic intrahypothalanic implantation of cyproterone, an antiandrogen, in male rats resulted in specific stimulation of testes, seminal vesicles, and prostates. Implantation of cholesterol-filled or empty tubes in the median eminence in controls was ineffective. We conclude that decreases in the amount of testosterone reaching specific receptors in the median eminence or in nearby regions activate a mechanism that produces increased gonadotropin secretion.


Neuromuscular transmitter substance in insect visceral muscle. Stimulation of the nerves innervating the proctodeum (hindgut) of the cockroach Periplaneta americana (L.) causes a slow-type, graded contraction of the longitudinal muscles. An unidentified substance, or substances, present in the foregut and hindgut, the specific activity of which is highest in the nerves innervating these organs, effects a similar contraction. This "gut-factor" is depleted from the hindgut after surgical section of the proctodeal nerves. None of Factors P(1) and P(2), 5-hydroxytryptamine, acetylcholine, adrenaline, noradrenaline, alpha-ami-nobutyric acid or glutamate duplicates the pharmacological behavior of this substance. The active factor is associated with subcellular particles that require centrifugal forces of approximately 1,000,000 g-min for sedimentation. The substance is inactivated in homogenates of gut tissue in the absence of suitable precautions. It is proposed that the "gut-factor" functions as an excitatory neuromuscular transmitter substance in insect visceral muscle.


Frog cerebellum: absence of long-term inhibition upon Purkinje cells. Electrophysiological studies of the cerebellar cortex of the frog demonstrate a lack of long-term inhibition upon the Purkinje cells. This lack of inhibition correlates well with the absence of stellate and basket cells in the molecular layer of this cerebellum and strongly supports the idea that these interneurones are the agents responsible for the prolonged inhibition seen in the Purkinje cells of other species.


Polonium-210 in bronchial epithelium of cigarette smokers.


Infrared absorption of carbonate apatite.


Some theoretical considerations in the treatment of homocystinuria.


The pathogenesis of homocystinuria. Implications for treatment.


Cystathioninuria: management.

Cystathioninuria: management.


Lysine intolerance with periodic ammonia intoxication.


Treatment of hyperglycinemia.

Treatment of hyperglycinemia.


Treatment of hyperammonemia.

Treatment of hyperammonemia.


Further studies on hyperlysinemia associated with retardation.


Studies on amino acid metabolism in citrullinuria.


Citrullinemia. A preliminary case report.


Treatment of arginosuccinic aciduria.

Treatment of arginosuccinic aciduria.


Arginosuccine aciduria.

Arginosuccine aciduria.


Treatment of hydroxyprolinemia and hyperprolinemia.


Membrane transport in disorders of imino-acid metabolism.


Radiological case of the month. Tyrosinosis.


Picture of the month. Wilson's disease (hepato-lenticular degeneration).


Hyperphenylalanemia without phenylketonuria.


Treatment of phenylketonuria.

Treatment of phenylketonuria.


Dietary treatment in tyrosinemia (tyrosinosis). With a note on the possible recognition of the carrier state.


Dietary treatment of tyrosinosis.

Dietary treatment of tyrosinosis.


Tyrosinosis.

Tyrosinosis.


Dietary treatment of maple syrup urine disease.


Hypoglycemia in maple syrup urine disease.


The therapy of maple syrup urine disease.


Isovaleric acidemia.

Isovaleric acidemia.


Clinical observations on phenylketonuria.


Acetophenetidin sensitivity.

Acetophenetidin sensitivity.


Salient features of histidinemia.

Salient features of histidinemia.


Hydroxykynureninuria.

Hydroxykynureninuria.


Variations in clinical and laboratory findings in histidinemia.


Homocystinuria. Trial treatment of a 5-year old severely retarded child with a natural diet low in methionine.


Dietary treatment of homocystinuria.

Dietary treatment of homocystinuria.


Precipitins in blastomycosis.

Precipitins in blastomycosis.


The prevalence of atypical mycobacterial tuberculin sensitivity in a selected population in New York City.


Lack of auramine-rhodamine fluorescence of Ruyon group iv Mycobacteria.


Effect of oxygen administration at low rates of flow in hypercapnic patients.


Results of long-term chemotherapy in spinal tuberculosis. XVII. A follow-up study of 235 patients.


Comparative pathogenicity of Mycobacterium avium and Battey bacilli.


Obstructive respiratory dysfunction in parkinsonian patients.


Acute effects of bilateral glomectomy on lung mechanics at rest and during induced airway obstruction.


One-stage combined diagnosis and therapy of intrathoracic tumors.


Comparative study of skin-test reactions to various mycobacterial antigens in Choctaw County, Oklahoma.


An epidemiologic assessment of a pediatric peak flowmeter.


An epidemiologic comparative study in Delaware of the Tine and Mantoux tests.


Response to inhaled histamine in bronchial asthma and in byssinosis.


Acute disseminated histoplasmosis.

Acute disseminated histoplasmosis.


Fatal pericarditis due to histoplasmosis. Report of a case.


The communication of affect in psychotherapy.


On necessary and sufficient conditions in psychiatric explanation.


Defensive and adaptive ego processes. Their relationship to GSR activity in free imagery experiments.


Psychiatrists' reliability in judging ego function.


On treating male homosexuals.

On treating male homosexuals.


The automation syndrome. The introduction of automation and its psychiatric consequences.


Family therapy.

Family therapy.


Individual thinking and family interaction. I. Introduction to an experimental study of problem solving in families of normals,  character disorders, and schizophrenics.


The lability of cutaneous neural elements.


Alcohol administration prior to sleep. The effect on EEG sleep stages.


"Teach-in" on factors controlling the blood supply of the epidermis.


"Beau's lines" in hair. Reduction of hair shaft diameter associated with illness.


A method for counting hairs.

A method for counting hairs.


Dermatomyositis.

Dermatomyositis.


Submucous fibrosis of the mouth.

Submucous fibrosis of the mouth.


Disseminated lupus erythematosus profundus.


Ventricular septal defect and congenital malformations of the urinary tract. Clinical indications for intravenous urography.


Sexual activity of children with other children and adults.


The haptoglobins and establishing paternity.


Large heads in small children. Notes on the causes of increased head circumference.


Little people moving to big cities: problems of health and survival.


Chondroectodermal dysplasia (Ellis-van Creveld syndrome). Report of two cases from Saudi Arabia.


Capillary and venous hematocrits in the newborn.


The use of the isolated annulus technique for the evaluation of intracardiac thrombosis.


Thyrocalcitonin treatment of experimental hyperparathyroidism in rats.


Altered host response to experimental pyelonephritis in alloxan diabetic rats.


Nitrogen mustard and growth of Brown-Pearce tumor.


Free amino acids in liver, plasma, and muscle of patients with cirrhosis of the liver.


Some psychiatric aspects of intracardiac surgery.


Indications for surgical treatment of chest-wall deformities in children.


A comparison of cultures of induced sputum and gastric washings in the diagnosis of tuberculosis.


Clinicopathologic Conference. Fever of undetermined origin. Résumé of a case.


Knuckle pads, leukonychia and deafness. A dominantly inherited syndrome.


Recognition of suicidal risks through the psychologic examination.


Medicine and politics.

Medicine and politics.


Case records of the Massachusetts General Hospital. Case 4-1967.


Contraceptive pills.

Contraceptive pills.


Card flocculation test in the field diagnosis of trichinosis.


A new medium, salt mannitol plasma agar, for the isolation of Staphylococcus aureus.


Initial experience with and potential of data processing and computer technics in a hospital clinical laboratory.


1963 prothrombin time test survey, College of American Pathologists, Standards Committee, Subcommittee on Coagulation.


Cr-51 red cell survival and corrections for hematocrit.


Measurement of renal function with radioiodinated diatrizoate and omicron-iodohippurate.


In vitro rabbit pancreas: effect of temperature on HCO-3, PCO-2, pH, and flow.


Diodrast transit time in guinea pig biliary tree.


Sodium chloride intake of adrenalectomized rats with lateral hypothalamic lesions.


Centrally induced vasoconstriction in rats and the influence of allergic encephalomyelitis.


CNS influence on plasma levels of factor 8 activity.


Emesis in horse serum anaphylactic shock in dogs.


Electrical activity of the rhinencephalon during high-altitude acclimatization.


Reproduction and growth of mice and rats under conditions of simulated increased gravity.


Blood gases and acid-base values of unanesthetized rats exposed to hypoxia.


Cold-induced changes in fatty acids of the rat and hamster.


Effects of insulin on amino acid release and urea formation in perfused rat liver.


Effects of insulin on net carbohydrate alterations in perfused rat liver.


Biosynthesis of glycoproteins: effect of injury on seromucoid fraction of rat plasma.


Effects of pentolinium on sodium excretion in dogs with constriction of the vena cava.


Behavior of isolated frog auricles in sucrose media.


Effects of fasting and feeding on uridine-3-H incorporation into RNA by pancreas slices.


Suppression and initiation of idioventricular automaticity during vagal stimulation.


Effects of denervation and fasting on white adipose tissue.


Countertransport of 3-O-methyl glucose in incubated rat epididymal adipose tissue.


Effects of fluoride and parathyroid extract on citrate and bone metabolism.


Effect of CO-2 and cations on fatty acid and cholesterol synthesis by liver in vitro.


Choline acetyltransferase and cholinesterase activities in muscle of dystrophic mice.


Mechanisms of bradycardia induced by digitalis substances.


Effect of hyperbaric oxygen on protein synthesis in the mammalian heart.


Development of arterial blood pressure in the chick embryo.


Pulsing blood flow in capillary tubes.

Pulsing blood flow in capillary tubes.


Effects of sodium chloride and bicarbonate in shock with metabolic acidosis.


Secretion of sodium by the resting, stimulated, and inhibited canine gastric mucosa.


Micropuncture study of isolated perfused rat kidney.


Glomerular and tubular effects of arginine vasotocin in water snakes (Natrix sipedon).


Intravenous pyelography. A comparative trial of ten methods in patients with good renal function.


Significance of fever in patients with malignant disease.


Influence of vagal stimulation on ventricular contractility, O2 consumption, and coronary flow.


Effect of propylthiouracil and I-131 on blood pressures of thyrotoxic patients.


Ultrasonic ablation of the labyrinth in the treatment of endolymphatic hypertension (Menier's disease).


The practicing surgeon in the role of skilled assistant.


The preparation and testing of horse antidog and antihuman antilymphoid plasma or serum and its protein fractions.


A study of cardiac vein negative pressure in arteriovenous fistula.


Reappraisal of digitalis. V. Evaluation of criteria for determining effect of digitalis in man.


Significance of T-loop change in vectorcardiographic diagnosis of left ventricular hypertrophy.


Unusual complication of barium studies. Report of case of adherent cecal barolith.


The mechanical nature of the heart as a pump.


Appendicitis: "functional" bowel obstruction associated with perforation of the appendix.


Iatrogenic jejunal ulcer.

Iatrogenic jejunal ulcer.


Combined percutaneous transhepatic cholangiography and angiography in the evaluation of obstructive jaundice.


Roentgen features of Hodgkin's disease of the stomach.


Inadvertent gastroileostomy.

Inadvertent gastroileostomy.


The esophagobronchial fistula. Case report and review of the literature.


The roentgen diagnosis of diffuse esophageal spasm.


A new technique of contrast examination of the nasopharynx with cinefluorography and roentgenography.


Segmental ulcerative colitis versus segmental Crohn's disease of the colon. A roentgenographic and pathologic study.


Ulcerative disease of the intestinal tract proximal to partially obstructing lesions. Roentgen appearance.


Duplication of the small bowel simulating regional enteritis.


An analysis of the normal anatomic relationships of the colon as applied to roentgenographic observations.


Chronic ulcerative colitis: diagnostic and therapeutic problems; a lifelong study.


Toxic megacolon in amebic colitis. Report of a case.


Roentgen diagnosis of intestinal amebiasis.


Lipomas of the gastrointestinal tract. An analysis of seventy-two tumors.


A hazard of silicone foam diagnostic enema. Report of a case of perforation of the colon.


Comparison of carboxy-methylcellulose, tannic acid and no additive in barium examinations of the colon.


Corynebacterial endocarditis. A report of two cases with review.


Some pitfalls of vectorcardiographic diagnosis of myocardial infarction with particular respect to emphysema.


Coronary artery disease. Physiological aspects and surgical therapy.


Significance of the initial R wave in lead aVR of the electrocardiogram in the diagnosis of myocardial infarction.


The dominant pacemaker of the human heart. Antegrade and retrograde activation of the heart.


Direct determinations of aortic blood flow in patients with aortic regurgitation. Effects of alterations in heart rate, increased ventricular preload or afterload, and isoproterenol.


The village care system in Nigeria.

The village care system in Nigeria.


Mycotic aneurysms of the intrapulmonary arteries.


Community agencies need hospital information.


The effects of varying oxygen concentrations on osteogenesis and embryonic cartilage in vitro.


Postoperative changes in regional pulmonary blood flow.


Live, attenuated mumps-virus vaccine. IV. Protective efficacy as measured in a field evaluation.


Live, attenuated mumps-virus vaccine. 3. Clinical and serologic aspects in a field evaluation.


Hyperglycemia after acute myocardial infarction. Its relation to diabetes mellitus.


Enigmatic fever and pelvic thrombophlebitis. Response to anticoagulants.


Some thoughts upon the discontents of the British general practitioner.


Positive concepts of privacy in research.


A comprehensive program of community mental health and retardation services.


Toward eradication of mumps.

Toward eradication of mumps.


Diabetes and myocardial infarction.

Diabetes and myocardial infarction.


Constipation.

Constipation.


Congenital megacolon.

Congenital megacolon.


Cancer of the gastrointestinal tract in childhood.


Congenital anomalies of the gastrointestinal tract.


"Midparent" values for use with parent-specific, age-size tables when paternal stature is estimated or unknown.


Inborn errors of metabolism.

Inborn errors of metabolism.


The child with recurrent abdominal pain.


Iodide transport: inhibition by agents reacting at the membrane. Accumulation of iodide by thyroid tissue is inhibited by two phospholipase A-free proteins from cobra venom, filipin, crude phospholipase C, and lysolecithin. The venom proteins decrease K(+) in tissue but do not significantly affect incorporation of phosphorus-32 into phospholipid or stimulation of this process by thyrotropin. However, filipin and crude phospholipase C, like thyrotropin, do increase phospholipid formation.


Passive transfer of tuberculin reactivity in vitro. A factor capable of effecting passive transfer in vivo of delayed hypersensitivity to tuberculin to recipients that are tuberculin negative was isolated from the dialyzate of disrupted leukocytes of tuberculin-positive individuals. After this factor was incubated with cultures of peripheral leukocytes from tuberculin-negative individuals, the addition of purified protein derivative of tubercle bacilli resulted in leukocyte stimulation similar to that observed after addition of purified protein derivative to leukocytes from tuberculin-positive individuals.


Seizure discharges evoked in vitro in thin section from guinea pig hippocampus. A thin section prepared from guinea pig hippocampus produced, in chloride-free medium, a train of seizure discharges in response to a single shock applied to the section. Generation of these discharges was ascribed to the lack of inhibitory processes in an absence of chloride ion.


The medical team in industry.

The medical team in industry.


The nurse in a small company views her responsibility.


The nurse in a large company views her responsibility.


Visiting nurse program in industry.

Visiting nurse program in industry.


Responsibility of the industrial nurse in a hearing conservation program.


Abuse of barbiturates, stimulants, LSD, as great a danger as illegal narcotics.


Cardiac emergencies in industry--nursing implications for the occupational health nurse.


Physicians' supervision of nurses in small plants adequate or inadequate.


A new dimension in nursing; intensive coronary care.


A glimpse of nursing in the USSR.

A glimpse of nursing in the USSR.


Tumors of the skin.

Tumors of the skin.


Nurse and pharmacist--partners.

Nurse and pharmacist--partners.


Estrogen and the menopause.

Estrogen and the menopause.


Radiation therapy for skin cancer.

Radiation therapy for skin cancer.


Why perform a hysterectomy?

Why perform a hysterectomy?


Catchment area--Europe; RAF Hospital, Wegberg.


Artificial kidneys: the tragic dilemma.

Artificial kidneys: the tragic dilemma.


Traumatic pneumothorax with gross surgical emphysema; nursing care study.


Periodic psychoses.

Periodic psychoses.


Space flight. 1.

Space flight. 1.


Nurse planners meet. The Hospital Centre.


Principles of haemodialysis.

Principles of haemodialysis.


Treatment of acute renal failure.

Treatment of acute renal failure.


Renal dialysis; where life depends on a machine.


How drugs act--second series. 1. Drugs and the parasympathetic nervous system.


Pre-frontal leucotomy.

Pre-frontal leucotomy.


Gross obsessional compulsive neurosis relieved by pre-frontal leucotomy.


Training hospital domestic forewomen.

Training hospital domestic forewomen.


Ambassadors for nursing.

Ambassadors for nursing.


No staffing problems here: Trinity Hospital, Taunton.


Conflict--one psychiatric register? For.


Space flight. 2.

Space flight. 2.


Conflict--one psychiatric register? Against.


More programmed teaching needed.

More programmed teaching needed.


Harrogate General Hospital.

Harrogate General Hospital.


The first of the second fifty.

The first of the second fifty.


Evidence on medical education.

Evidence on medical education.


Trends in treating breast cancer.

Trends in treating breast cancer.


The menace of breast cancer.

The menace of breast cancer.


Nursing care of neurosurgical patients--admission and discharge.


Neurosurgery today. 1.

Neurosurgery today. 1.


How drugs act--second series. 2. Drugs and the heart.


Teaching the teachers; Bolton College of Education (Technical).


A chronic schizophrenic rehabilitated; nursing care study.


A minor gynaecological operation with unexpected complications.


Teacher to student.

Teacher to student.


Taped interviews in psychiatric nurse training.


Nursing care of neurosurgical patients; post-operative care.


Improving patients' clothing--and laundry services.


How drugs act. 3. Diuretic drugs.

How drugs act. 3. Diuretic drugs.


Siglap, Singapore.

Siglap, Singapore.


'Exam nerves'--or 'State fever'.

'Exam nerves'--or 'State fever'.


Dial MANsion House 9000. The Samaritans.


The Hospital Centre: discussion group. Geriatric day hospitals.


The rope: a study of an elderly deaf patient.


Transatlantic viewpoint.

Transatlantic viewpoint.


Making a manager.

Making a manager.


Accidents and the elderly.

Accidents and the elderly.


A child who swallowed furniture oil; a nursing care study.


Neurosurgery today. 3. Head injuries.

Neurosurgery today. 3. Head injuries.


Music therapy in a neurosis centre.

Music therapy in a neurosis centre.


First-line management.

First-line management.


How drugs act. 4. Drugs and the blood.

How drugs act. 4. Drugs and the blood.


Incontinence and the geriatric patient. 1. Understanding the problem.


Rcn Tutor Section winter conference: drugs and addiction.


Books or machines? Conference at The Hospital Centre.


Paul is very ill; prizewinning nursing care study.


Educational television.

Educational television.


First in the field: Ipswich Civic College; clinical instructors' course.


Neurosurgery today. 4. Subarachnoid haemorrhage.


Cut: take one. Making a hospital filmstrip.


Getting nurses to use the library.

Getting nurses to use the library.


Incontinence and the geriatric patient. 2. solving the problem.


Students' needs: a tutor's view.

Students' needs: a tutor's view.


Clinical Instruction. 1. The clinical instructor and the school of nursing.


Working together.

Working together.


Good with patients: bad with people.

Good with patients: bad with people.


Immunization by nurses.

Immunization by nurses.


Nurse recruitment.

Nurse recruitment.