Feeding the ill and weak.

Feeding the ill and weak.


How drugs act. 6. Drugs and anesthesia.

How drugs act. 6. Drugs and anesthesia.


Hyperbaric oxygenation.

Hyperbaric oxygenation.


Hyperbaric oxygenation--a new field opened for nurses.


Programmed learning: progress report.

Programmed learning: progress report.


Transatlantic nursing.

Transatlantic nursing.


Clinical instruction. 2. The clinical instructor and the ward sister.


VAD.

VAD.


European Working Group: Europeans all.

European Working Group: Europeans all.


Private nursing--further training?

Private nursing--further training?


Characterization of the normal serum glutamic-oxalacetic transaminase activity of healthy adults.


Hypersarcosinemia. A newly described inborn error of metabolism.


Hereditary tyrosinemia and tyrosyluria in a French Canadian geographic isolate.


The early treatment of phenylketonuria.

The early treatment of phenylketonuria.


A hazard of cuffed endotracheal tubes.

A hazard of cuffed endotracheal tubes.


Unilateral epidural analgesia.

Unilateral epidural analgesia.


Tetany during deep halothane anaesthesia.


A streamlined cuffed nasal endotracheal tube.


A warning device for failure of the oxygen supply.


A modified Ayres T--piece.

A modified Ayres T--piece.


The relative potencies of methohexitone and thiopentone. A statistical study in man.


Editorial.

Editorial.


A new intramuscular anaesthetic for small children. A report of clinical trials of CI-581.


Anaesthesia for mass casualties. Another possible solution for disaster circumstances.


The effects of sedation on the digital plethysmogram. A radiotelemetric study of haloperidol.


The evaluation of oxygen masks. A mechanical method.


Subjective assessment of analgesics.

Subjective assessment of analgesics.


The community mental health program and the longer-stay patient.


Propranolol in hypotensive anaesthesia.

Propranolol in hypotensive anaesthesia.


The natural history of umbilical hernia. A six-year follow up of 314 Negro children with this defect.


Toilet training and "the terrible two's". Comments on the prevention and management of behavior problems at this age.


Effect of curare on canine micturition.

Effect of curare on canine micturition.


Cancer of the penis in India.

Cancer of the penis in India.


Steroid injection therapy for Peyronie's disease: a 10-year summary and review of 38 cases.


Complications of punch biopsy of the prostate gland.


Comparison of the perineal needle biopsy and the transurethral prostatectomy in the diagnosis of prostatic carcinoma: an analysis of 300 cases.


Translumbar amputation for advanced leiomyosarcoma of the prostate.


Transurethral resection of the prostate with an in situ internal cardiac pacemaker.


Prostatic fluid analysis and prostatitis.


Effectiveness of urea in prophylaxis of experimentally induced bacteriuria in rats.


Cephaloridine: a new broad spectrum antibiotic. Effectiveness in urogenital infections.


Treatment of urinary tract infections with cephaloridine.


A fiberoptic ultraviolet cystoscope.

A fiberoptic ultraviolet cystoscope.


Electronic data processing in the study of renal cortical tumors.


Unilateral renal damage due to massive contrast dye injection with recovery.


Effect of irradiation on renal function.


The diagnosis of renal tumors by radioisotope scanning.


Xanthogranulomatous pyelonephritis in the paraplegic.


Avulsion of distal ureter with dormia basket.


Spontaneous peripelvic and periureteral extravasation associated with pregnancy.


Variations in reflux related to bladder volume and body surface area.


Clinical experience with a radio-linked bladder stimulator.


Electrical stimulation of human neurogenic bladders: experience with 4 patients.


Rectovesical fistula following an ovarian dermoid with recurrent vesical calculus: a case report.


Ballottement of peripelvic cyst for operative diagnosis and localization.


Papillary transitional cell tumor of bladder in a 5-year-old boy.


Aneurysm of hypogastric artery presenting with bladder neck obstruction.


Multiple hemangiomas of the male urethra--treatment by Denis Browne-Swinney-Johanson urethroplasty.


An effective control of benign enuresis.


Phenylketonuria in the American Indian.

Phenylketonuria in the American Indian.


A study of the effect of the mother's presence during anesthesia induction.


American Academy of Pediatrics. President's address.


Diagnosis and treatment: useful preliminaries to contrast x-ray examinations in children. With comments on technique.


Dangers of hydrogen peroxide in enemas or lavage.


Stokes-Adams attacks in a small child treated by prolonged use of an indwelling pacing catheter.


The reversibility of pulmonary hypertension in patients with cystic fibrosis. Observations on the effects of tolazoline hydrochloride.


Hepatosplenomegaly and heart disease in the congenital rubella syndrome. Report of eight cases.


Sudden, unexpected death in infancy. With special reference to the parathyroids.


Central nervous system complications following Blalock-Taussig operation.


Early surgical correction of large ventricular septal defects.


Lipid metabolism in the newborn. I. Phospholipids in cord and maternal sera.


Mosaicism of an abnormally long B chromosome in a boy with physical and mental retardation.


Placing and grasping of the feet at various temperatures in early infancy.


Lateral hypothalamus: hoarding behavior elicited by electrical stimulation. Electrical stimulation of those points in the lateral hypothalamic area of the brain that promote feeding, but not of other points, elicited intense hoarding activity in satiated rats, similar to that produced by long-term food deprivation. This result suggests that hoarding of food is organized by a hypothalamic drive mechanism sensitive to the efflects of long-term nutritional depletion.


Opposite synaptic actions mediated by different branches of an identifiable interneuron in Aplysia. Among the identifiable cells in the abdominal ganglion of Aplysia californica are five that generate bursting rhythms endogenous to the cells. In the four bursting cells of the left upper quadrant the rhythm is modulated by a unitary inhibitory postsynaptic potential; in the bursting cell of the right lower quadrant the rhythm is modulated by a unitary excitatory postsynaptic potential. Both the excitatory and inhibitory postsynaptic potentials are mediated by separate branches of a single interneuron. The pharmacological properties of the double action interneuron as well as those of the follower cells suggest that a single transmitter (acetylcholine) is involved in both the excitatory and the in-hibitory action of the interneuron.


Axonal delivery of neuroplasmic components to muscle cells. Substances labeled with phosphate-32 and carbon-14 and applied to hypoglossal nuclei in rabbits traveled down the hypoglossal nerves and after several days began entering only the muscle cells of the tongue. Prevention of axonal delivery on one side caused unilateral labeling of the tongue. Labeled substances delivered by extracellular fluids labeled all cells indiscriminately. The axonal conveyance of neuroplasmic components to peripheral cells may provide a basis for trophic influences of neurons on other cells.


Mechanism of delayed reactions.

Mechanism of delayed reactions. Arsanilic acid conjugates of polymers of L-typrosine, glutamic acid, and alanine are immunogenic and can elicit hapten-specific, delayed-hypersensitivity reactions in sensitized guinea pigs. Conjugates of the D-amino acid polymers are neither immunogenic nor capable of eliciting delayed reactions. Mixtures of small amounts of conjugates capable of eliciting a delayed reaction with larger amounts of D-amino acid polymer conjugates produce only small delayed reactions. I suggest that the delayed reaction is an active response requiring the continued participation of immunogenic material in sensitized animals; it is not the reaction of preformed antibody-like material with the antigenic determinant.


Acute leukemia presenting as nasal obstruction.


Optical environment in Gemini space flights.


Side-rail clamp for Killian-Lynch suspension laryngoscope.


Oxytetracycline-treated packing.

Oxytetracycline-treated packing.


Sensorineural deafness.

Sensorineural deafness.


Pseudocysts of the auricle in Caucasians.


A guide to newborn and infant hearing screening programs.


The Year of the Big Look.

The Year of the Big Look.


Detection of hearing loss in neonates.

Detection of hearing loss in neonates.


Vocal rehabilitation for contact ulcer of the larynx.


The safety of mediastinoscopy.

The safety of mediastinoscopy.


Fibrous dysplasia of the middle ear. A case report.


The nasal cavity in complete unilateral cleft lip and palate.


Midfacial cysts.

Midfacial cysts.


Treatment of velopharyngeal incompetence.


Radiated homogenous cartilage in rhinoplasty.


Carotidynia. A distinct syndrome.

Carotidynia. A distinct syndrome.


Posttraumatic anosmia.

Posttraumatic anosmia.


The hot tongue syndrome. Etiology and treatment.


Tonsillectomy and hemoglobin C-C disease.


Multiple valve replacement.

Multiple valve replacement.


Closure of ventricular septal defect following myocardial infarction.


Aortoiliac steal syndrome and necrosis of gastrointestinal tract.


Sodium heparin neutralization and the anticoagulant effects of protamine sulfate.


Thermal blanket injury in the operating room.


Cyanoacrylate tissue adhesive in surgery in anticoagulated subjects. Study in immediate postoperative bleeding.


Hemorrhagic shock. Changes in renal blood flow and vascular resistance.


Temperature of the hand during and following surgery.


Cineradiographic studies of abnormalities of the high cervical spine.


Nasopharyngeal carcinomas in children.

Nasopharyngeal carcinomas in children.


The effect of edema and external pressure on wound healing.


Thyroid carcinoma arising in thyroglossal duct remnants. Report of a case and review of the literature.


The regional use of muscle relaxants.

The regional use of muscle relaxants.


Significance of mediastinoscopy in carcinoma of the lung.


Intra-arterial chemotherapy in advanced pelvic tumors.


A depressive syndrome following pelvic exenteration and ileostomy.


Portal hypertension with anomalies of inferior vena cava and hepatic veins.


Influence of hypothermia on the course of experimental pancreatitis.


Amino acids mixtures in prevention of acute ammonia intoxication in dogs.


Hemocholecyst. A case report.

Hemocholecyst. A case report.


Gastric actinomycosis. Case report.

Gastric actinomycosis. Case report.


Pyloric obstruction by a phytobezoar following pyloroplasty and vagotomy.


Duplication of the duodenum in the adult.


Simultaneous bilateral torsion of the testes in a newborn infant.


Dogs versus sheep as hemorrhagic shock models.


Systemic venous reactivity.

Systemic venous reactivity.


Subcutaneous storage of autogenous veins.


Prognosis in hyaline-membrane disease. Use of a linear-discriminant.


Insulin secretion in obesity.

Insulin secretion in obesity.


Statistical ward rounds--1.

Statistical ward rounds--1.


Therapeutic effects of pentaerythritol tetranitrate in the immediate postmyocardial-infarction period.


Hepatic effects of oral contraceptives.

Hepatic effects of oral contraceptives.


One facet of neural regulation.

One facet of neural regulation.


Discrimination in the premature nursery.


Erythema nodosum and contraceptive medication.


Combined x-ray and gamma-radium ray therapy for skin cancer.


Allergy to penicillin.

Allergy to penicillin.


Continuous arterial infusion chemotherapy for lymphoma and other cutaneous malignant tumors.


Effect of dactinomycin on pathogenic fungi with special reference to experimental cryptococcosis.


Pyoderma gangrenosum. A patient successfully treated with intralesional injections of steroid.


Angioma serpiginosum.

Angioma serpiginosum.


Effects of pesticides on drug and steroid metabolism.


A quantitative evaluation of the neurospasmolytic effect of orphenadrine by direct and telemedographed electromyography.


Correlation of the nalorphine test with concentration of metabolites of codeine in the urine after single doses and continuous administration of codeine.


The association of blue rubber bleb nevus and Maffucci's syndrome.


Erythema annulare centrifugum due to hydroxychloroquine sulfate and chloroquine sulfate.


Purpuric eruptions associated with use of carbromal and meprobamate.


Contact dermatitis due to spandex.

Contact dermatitis due to spandex.


Borderline leprosy. Case report of a patient with erythema nodosum and hepatic lepromas.


Hematogenous dissemination in chromoblastomycosis. Report of a generalized case.


Tumbu-fly myiasis in Marshfield, Wis.

Tumbu-fly myiasis in Marshfield, Wis.


Morphea-like basal cell epithelioma in a child.


Erythema gyratum repens and undifferentiated carcinoma.


Basal cell carcinoma of the mandibular gingiva.


Perianal keratoacanthoma.

Perianal keratoacanthoma.


Boric acid intoxication from "medicated talcum powder".


Allergic, contact-type dermatitis due to spandex in brassiere.


Osler's node of subacute bacterial endocarditis. Focal necrotizing vaculitis of the glomus body.


Bilateral Mondor's disease.

Bilateral Mondor's disease.


Congenital phlebectasia. A histopathologic study.


Alanine aminotransferase. II. The basis for substrate specificity.


The identification of carnitine palmityltransferase in erythrocyte membranes.


Homocysteine and cysteine synthetases of Neurospora crassa. Purification, properties, and feedback control of activity.


Inhibition of bacteriophage T4 deoxyribonucleic acid maturation by actinomycin D. The accumulation of "replicating deoxyribonucleic acid".


Metabolism of formiminoglycine. Formiminotetrahydrofolate cyclodeaminase.


Deoxyribose 5-phosphate aldolase. II. Purification and properties of the rat liver enzyme.


Inhibitors of protein synthesis in rat liver microsome fractions.


Carnitine decarboxylase. The conversion of carnitine to beta-methylcholine.


Correlation of light-induced absorbance changes with photo-phosphorylation in Rhodospirillum rubrum extracts.


Reversible disruption by cupric ions of myoglobin and its carboxamidomethyl derivative.


Intramitochondrial metabolism of phosphoenolpyruvate.


The enzymatic cleavage of the carbon-nitrogen bond in 3-alpha, 7-alpha, 12-alpha-trihydroxy-5-beta-cholan-24-oylglycine.


Alanine aminotransferase. I. Purification and properties.


Outpatient pharmacy automation.

Outpatient pharmacy automation.


Pharmacy automated data processing system by mail.


Preparation of an inventory deck and a drug locator list by electronic data processing.


Long-acting diethylstilbestrol injections.


An equipment maintenance program for hospital pharmacy.


An outline for preparing ophthalmic solutions.


Activated charcoal as an antidote for poisons.


The compleat pharmacist.

The compleat pharmacist.


Hexamic acid as a component of potassium gluconate and glyceryl guaiacolate solutions.


Electronic data processing and the hospital formulary.


Progestogen-estrogen therapy in the menopause. A double blind study.


Trichomonal vaginitis: epidemiology and therapy.


Endocrine factors in endometrial carcinoma. A preliminary report. This prospective study determines the presence of a consistent endocrine disturbance in patients with endometrial carcinoma.  A major requirement of the study was an unbiased control group matched as to age, race, economic status, and primary reason for referral.  All patients with untreated endometrial carcinoma or postmenopausal bleeding were studied and grouped into:  1) endometrial carcinoma (n=56), and 2) atrophic endometrium (n=83), or the "bleeding" controls.  Average age of patients with carcinoma was 63.9 years and that of controls, 61.3 years.  Factors studied were glucose metabolism, estrogenic activity, gonadotropin excretion, obesity, hypertension, time of climacteric, fertility, and menstrual history.  By averaging deviations from ideal weight, cancer patients were found to be 13.1 pounds heavier than the control group (49.8 pounds vs. 36.7 for the controls).  Analysis of fertility data showed that age at time of marriage in patients who were parous compared with those who were nulliparous was 20.1 and 26.8 years respectively for the carcinoma group, and 20.4 and 27.5 years for the bleeding controls.  Of parous cancer patients, 6.3% used contraception vs. 13% of the controls.  These data do not suggest that pregnancy prevention by late marriage or contraception plays a significant role in the later development of endometrial carcinoma.  Hypertension, time of menopause, diabetes, estrogenic activity, and gonadotropin excretion did not exhibit significant effects in the development of carcinoma.  The findings support those of Corscaden, Fertig, and Gusberg that obesity and infertility are statistical concomitants with endometrial carcinoma but contradict current belief that there is direct evidence of abnormal endocrine state (e.g., glucose metabolism, estrogen stimulation, or anterior pituitary activity).


Comparative validity of oral and intravenous glucose tolerance tests in pregnancy. A study of 144 patients tested both during pregnancy and in the nonpregnant state.


Tubal sterilization. Study at Evanston Hospital. This article presents a review of 902 tubal sterilizations performed in an 18 1/2-year period at a predominantly private teaching service.  803 (89%) of the sterilizations were puerperal, generally performed within 48 hours of delivery or with cesarean section.  The Pomeroy technique (often modified) was used in 97.2% of the puerperal sterilizations; the other surgical methods included the Madlener operation, total salpingectomy, the Adridge procedure, and cornual excision.  Indications for sterilization were obstetrical in 691 cases, medical in 58 cases, neuropsychiatric in 27 cases, socioeconomic in 10 cases, and genetic, orthopedic, or surgical in the remaining cases.  Multiparity was the most frequently cited indication (419 cases).  The patients' age range was 19-44 years, with the largest number of acceptors (67.2%) in the 30-39 year age group.  Until 1962, written approval of a qualified consultant was required in addition to the consent of the patient and her spouse.  Since 1962, sterilization requests have been considered by a Hospital Sterilization Committee comprised of 3 obstetricians.  There were 5 failures (.55% pregnancy rate) in this series of 902 sterilizations and no deaths.


Carpal tunnel syndrome in pregnancy.

Carpal tunnel syndrome in pregnancy.


Amniotic fluid oxygen tensions in severe maternal anemia.


The changing impact of pulmonary thromboembolism in obstetrics. Value of the isotopic perfusion scan.


An evaluation of ultrasonic fetal cephalometry.


Acute superficial venous thrombophlebitis associated with pregnancy.


Sickle cell thalassemia in pregnancy.

Sickle cell thalassemia in pregnancy.


Recurrent Chiari-Frommel syndrome following 3 pregnancies.


Mixed mesodermal tumor of the ovary.

Mixed mesodermal tumor of the ovary.


A study of the neural control of sexual clasping behaviour in Rana angolensis bocage and Bufo regularis reuss with a consideration of self-regulatory hindbrain systems in the Anura.


Strain differences in maternal behavior in rats.


A study of problem solving by gibbons.

A study of problem solving by gibbons.


The MLA exchange: a report.

The MLA exchange: a report. This report on the MLA Exchange presents a history of the Exchange, an outline of its operation, an explanation of why it operates, information on the cost to the Association and its members of acquiring and mailing pieces through the MLA Exchange, and a description of the duties of the Exchange Committee. MLA members are asked to submit suggestions to the Committee for consideration and to abide by the Procedures Manual in submitting lists of duplicates, requesting duplicates, assigning and shipping duplicates, acknowledging receipts, and repaying postage.


Austere librarians--volte-face.

Austere librarians--volte-face. Medical Libraries are too concerned with their customers and not interested enough in their wares. The number, nature, behavior, and satisfaction of readers and the book use by readers are extensively analyzed. Though important for library operation, such studies tend to make library staff regard and treat readers as impersonal members of a study population. As opposed to critical analysis of readers, little effort is made in this direction with respect to journals. It is, therefore, proposed that medical libraries take a hard look at the journals they offer and classify and display them in A, B, C, and D categories. The following benefits might be envisioned: the reader would be helped in looking up a subject that is not in his immediate field of specialization, the occupancy of valuable space by poor journals would be prevented, medium quality journals would strive to improve themselves, and it is even possible that poor and superfluous journals would be put out of business.


The National Library of Medicine's services: initial observations on indexing, interlibrary loan, and reference. How have the three services-indexing, reference (including history of medicine), and interlibrary loan-been provided throughout the years by NLM, and how have they been used? At the present time of great growth and development, the use of the computer has influenced these services and will continue to figure prominently in plans for the future. NLM's services often have not been well or correctly used by its public, even by librarians. Some of its services, however, need to be provided in more depth and on a higher scale, and they should be publicized more widely. History shows that NLM has been faithful to its basic charge and has gone far beyond it in its service to the medical, educational, and library communities. Medical librarians are most fortunate that such a great national resource exists to provide materials and services to fulfill the needs of their libraries.


Establishing a medical library network for the Metropolitan Detroit Area. Since 1962 the members of the loosely organized Detroit Medical Library Group have carried on a slow but steady self-examination program. They found a need to increase resources and developed a periodical exchange, then a need to identify these resources and did so by means of a serials list. More recently, a similar program for texts and monograph resources was begun. Data, more particularly that of the interlibrary loan process, is being gathered to show the flow within the area and the flow from outside to further identify the existing resources. They have made contact with the administrators of the biomedical institutions and gained their backing (a) to further study the makeup of the community and (b) to formulate an administrative structure through which these institutions can act. These activities are evidence of the beginning of a strong medical library network for the Metropolitan Detroit Area.


The program of the Francis A. Countway Library of Medicine. The planning of the Countway Library took place in an atmosphere of community interest and support. Architectural planning was effective and harmonious. The building functions well. The program of the Library is briefly described. Serials records, involving 17,000 titles, have been mechanized. A rare books program has been initiated. Since building occupancy, the Library has substituted copy service for the lending of periodicals. For an experimental period, the copy service was cost free. The Aesculapian Room, for non-medical recreational reading, has had the generous support of the Aesculapian Club. Plans for regional library service in New England are based upon an historic commitment of the Boston Medical Library. A MEDLARS regional search center and a national Vision Information Center have been established in the Countway.


Stimulating growth and development of medical society libraries. A library can represent the most valuable personal service which a medical society can offer to a physician; yet, libraries unfortunately are taking a lessening role in medical societies. Surveys show that medical society libraries have declined in number from seventy-one in 1942 to forty-eight at the present time. This paper offers a positive plan of action with the objective of enabling libraries to regain a position of eminence in medical societies. It is pointed out that there are four vital elements in stimulating the growth and development of a library. These are the constant enhancement of resources; the promotion of library services; the rendering of prompt, valuable services; and ultimately, the recognition of the library through gifts, endowments, and expressions of appreciation.


A medical society trustee looks at his library. Speculative expression has been given to the idea that physicians should prove their continuing education by periodic examinations. With this thought in mind, it was decided that the Denver Medical Society Library should be continued and supported for at least ten years and, that at the end of this time, the entire situation would be re-evaluated in connection with the changing trends in medicine.


Revision of the Wayne State University Medical Library subject catalog using the 1966 Medical Subject Heading system. Wayne State University Medical Library (WSUML) revised its monograph subject catalog in 1961 utilizing the 1960 edition of MeSH as an authority list. With the introduction of MEDLARS in 1963 by NLM, all topical subheadings were omitted from MeSH. Inasmuch as this omission could not accommodate the needs of WSUML, the 1960 edition of MeSH was retained as a guideline. In January 1966, when MeSH resumed the incorporation of topical subheadings, WSUML was faced with a decision whether to continue the current policy or to adopt the form as presented in the latest edition of MeSH. This report describes the methodology employed in adopting a new policy, the findings which resulted from the change, and an evaluation of this reorganization.


MLA certification: the certification program and education for medical librarianship. The certification program was formally adopted by the Medical Library Association in 1948 in an attempt to establish standards for medical librarians. The program is reviewed, and some of its effects on education for medical librarians are discussed. At the time of its adoption the program defined the kind of education librarians in the field thought necessary for work in medical libraries. New techniques and a shortage of personnel demand consideration of new educational programs, and the Medical Library Assistance Act will provide the means for their establishment. The Association should assume leadership in determining what and where these programs should be and should evaluate its certification and standards programs as often as current needs require.


An index to medical book reviews: a computer experiment. The experimental production of an index to book reviews of medical publications is described. Details of compilation and preparation of data for processing by an IBM 1440 computer are outlined. Results of a survey testing the response to the index in its present form by medical libraries are presented.


The hard sciences and the soft: some sociological observations. The paper focuses on the implications of the terms "hard" and "soft" as they are used to characterize different branches of science; this is one approach to understanding some of the relations between knowledge and social organization. Given the importance to scientists of having their work evaluated accurately, it can be seen that the more rigorously a body of knowledge is organized, the more readily professional recognition can be appropriately assigned. The degree of rigor seems directly related to the extent to which mathematics is used in a science, and it is this that makes a science "hard." Data are presented in support of the hypothesis that "harder" sciences are characterized by more impersonality in their members' relationships where impersonality is indexed by the frequency that only first initials are used in footnotes. Finally, some parallels between the economic and the scientific sectors of society are suggested, viewing money and professional recognition as "generalized media" and noting certain analogies in science to inflation and deflation in the economic system. Implications for the obsolescence of parts of the literature of science are discussed, and the relevance of this analysis to Kuhn's work on scientific revolutions is briefly noted.


Training for library technicians.

Training for library technicians.


The control of estuarine pollution.

The control of estuarine pollution.


MLA certification: its present problems and future development. The certification program is reviewed and questions as to the validity of the existing three grades of certification are raised. Large institutions which employ many medical librarians do not officially recognize the certificates. The three types of certificates should be replaced with one certificate or diploma. Problems of meaningful examinations, lack of training facilities, and revision of the curriculum require attention. A program is proposed for the improvement of education for medical librarianship. Public identification of medical librarianship is presently difficult.


Chorioretinal vascular occlusions with latex microspheres (a long-term study). II.


Enzymes of carbohydrate metabolism in developing galactose cataracts of rats.


The role of Na+ ions in the transport of alpha-aminoisobutyric acid and other amino acids into the lens.


Electrical evidence on the trichromatic theory. The Jonas S. Friedenwald Memorial Lecture.


Measurement of aqueous humor formation rates by posterior-anterior chamber perfusion with inulin: normal values and the effect of carbonic anhydrase inhibition.


The rate of aqueous humor formation in buphthalmic rabbit eyes.


A continuous sampling technique for quantitatively measuring transcorneal penetration in vivo.


Studies on peripheral circulatory and metabolic consequences of thyrotoxicosis.


Hemiplegic amyotrophy: a preliminary report with case presentations and review of the literature.


Temporal (cranial) arteritis.

Temporal (cranial) arteritis.


Self-help in rehabilitation. Some theoretical aspects.


The process of organizing a program for the employment of the mentally retarded in a state civil service system.


Parotid tumors.

Parotid tumors.


Recovery following D-C shock for 200 episodes of ventricular tachycardia-fibrillation.


Acute hemorrhagic leukoencephalitis. Report of 2 cases.


Bacterial endocarditis: pathogenesis and racial susceptibility.


Electrocardiographic recognition of left ventricular overwork.


Reversible Cushing's syndrome caused by a bronchial adenoma.


Clinical evaluation of thyroid scanning with particular emphasis in detection of cancer.


Aberrant right subclavian artery.

Aberrant right subclavian artery.


Gentamicin sulfate in the treatment of extra-urinary infections due to gram-negative bacteria.


The overuse of phenacetin as a cause of renal papillary necrosis.


The prognostic value of the trimethaphan test.


Brucellosis causing fever and bone marrow granulomas.


Medical grand rounds from the University of Alabama Medical Center.


Bowenoid conditions of the skin: treatment with topical 5-fluorouracil.


Some psychiatric considerations in the care of college students.


Postauricular subperiosteal abscess in chronic otitis media.


Amniography in the intra-uterine transfusion: demonstration of an intestinal obstruction in a newborn.


Postpartum evaluation of two rectal suppositories for bowel evacuation.


One year's experience in the isolation of atypical mycobacteria at the Veterans Administration Hospital, Houston: epidemiological and clinical inferences.


Lincomycin therapy of pneumonia: clinical experience with 50 patients.


Preoperative assessment of aortic regurgitation in patients with mitral valve disease.


Left ventricular hemodynamics in mitral stenosis.


Hemodynamics one year following mitral valve replacement.


A study of the period of isovolumic relaxation in normal subjects and in patients with heart disease.


Studies in P wave synchronization.

Studies in P wave synchronization.


Left ventricular mass. A comparison of angiocardiographic measurements with autopsy weight.


Recording actual heart movements and arterial pulsations with a new electronic device.


The use of quinidine in cardioversion.

The use of quinidine in cardioversion.


Pseudotruncus arteriosus. A review of 21 cases with observations on oldest reported case.


Anomalies of the cardiac valves associated with complete transposition of the great vessels.


Fat infiltration of myocardium as a cause of cardiac conduction defect.


A case of valvular and supravalvular aortic stenosis and coarctation of the aorta.


Complete atrioventricular block associated with atrial septal defect of the fossa ovalis (secundum) type. A histopathologic study of the conduction systems.


Rupture of an aneurysm of the sinus of valsalva into the right atrium. Observations using a catheter-tip micromanometer-microphone.


Heart sounds in atrial flutter-fibrillation.


Spontaneous physiologic closure of an atrial septal defect after infancy.


Audible atrial sounds in a case of atrial flutter.


Corrected transposition of the great vessels with isolated pulmonic stenosis. The paradox of pulmonic stenosis with physical signs of pulmonary hypertension.


Standard footprinting technics termed valueless.


O. R. housekeeping problems.

O. R. housekeeping problems.


Planned, complete C.S. orientation minimizes employee fears, errors.


Electronic age bids new professional to hospital team.


Hospitals in boxes.

Hospitals in boxes.


Can nursing-home patients be fireproofed?


Product analysis and hospital purchasing.


Nursing shortage: reality or illusion?

Nursing shortage: reality or illusion?


Medical staff counselors aid nursing students.


Interns, residents vulnerable to malpractice charges.


The seven-day hospital: study shows potential benefits.


The auxiliary's role in a public-relations program.


Why patients break appointments.

Why patients break appointments.


Pest-control measures.

Pest-control measures.


Clinical applications of isoenzyme analysis.


Documentation provides basis for budget requests.


A child dies.

A child dies.


A report on 17 years' experience with early introduction of solids.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Normal laboratory values.


Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 3-1967.


Teaching diabetic self-care.

Teaching diabetic self-care.


Smallpox vaccine--risks and needs.

Smallpox vaccine--risks and needs.


Poisoning by venomous animals.

Poisoning by venomous animals.


Mycosis fungoides with pulmonary and neurologic complications.


Hypopituitarism with normal or increased height. Report of two cases, with measurement of plasma growth hormone levels.


Primary defective iron reutilization. Response to testosterone therapy.


Epidemiology of gout and hyperuricemia. A long-term population study.


Effect of food, fast and alcohol on serum uric acid and acute attacks of gout.


Argininosuccinic aciduria. Report of two new cases and demonstration of intermittent elevation of blood ammonia.


Ovarian cortical stroma, a steroid-dependent tissue.


Reappraisal of residual ovaries.

Reappraisal of residual ovaries.


Mode and site of action of clomiphene.

Mode and site of action of clomiphene.


Diagnosis of latent urinary tract infections in pregnancy. Study of the iron sorbitol citric acid provocative test.


Comparison of acid-soluble nucleotides across human placenta.


Whole blood oxygen affinities of women with various hemoglobinopathies.


Premature menopause in XO-XX-XXX-XXXXX mosaicism.


Ceruloplasmin and 5-hydroxyindole metabolism in pregnancy.


Further evidence for cyclic activation of the heterochromatic X chromosome in human females.


Variable response to treatment of the polycystic ovary.


Chromosome anomalies as a cause of spontaneous abortion.


Carcinoma of the endometrium in Saskatchewan. A review of 603 cases with a suggested scheme of management for patients with Stage I disease and regarded as good surgical risks.


Therapeutic abortion. A 12 year review at the Toronto General Hospital, 1954-1965.


Rupture of the uterus.

Rupture of the uterus.


Intrauterine fetal transfusions for erythroblastosis. A report on 100 consecutive operations.


The effect of epidural anesthesia on oxytocin-induced labor.


Optimum conditions for administration of single-shot caudal anesthesia.


Continuous paracervical block.

Continuous paracervical block.


Heparin in the treatment of hypofibrinogenemia complicating fetal death in utero.


Dilemmas in adoption: case studies of the adoptive process illustrating the role of the caseworker.


Congenital malformations and perinatal mortality in Bombay.


Fatty acid composition of serum lipids in pregnancy and gynecologic cancer.


An electron microscopic study of steroid induced reticuloendothelial blockade.


Studies on homotransplantable lymphomas in hamsters. 3. Further observations on the specificity of the histologic responses in lymphoid tissues and their relationship to metastasis.


The role of the endothelium in the initial phases of thrombosis. An electron microscopic study.


The ultrastructure of early platelet aggregation in vivo.


Pathogenesis of foam cell lesions in irradiated arteries.


An electron microscopic study of the alveolar-capillary wall following intratracheal administration of saline and water.


A naturally occurring outbreak of Candida tropicalis infection in a laboratory mouse colony.


The effects of glucocorticoids on red and white muscles in the rat.


The ultrastructure of medullary and scirrhous mammary duct carcinoma.


Enterocutaneous fistulas involving the jejuno-ileum.


Volvulus of the cecum.

Volvulus of the cecum.


Retroperitoneal ligation of the hypogastric arteries for pelvic hemorrhage.


Supraclavicular metastases from testicular tumors treated by surgery and irradiation.


Brain scan and twist drill needle biopsy of metastatic brain tumors.


Cryosurgical technics in head and neck surgery.


Acoustic neuroma: a misnomer.

Acoustic neuroma: a misnomer.


Monitoring and managing the patient during vascular surgery.


Myocardial revascularization after experimental bilateral internal mammary artery implantation.


Mediastinal biopsy: the direct approach.


Hemorrhagic telangiectasia. Report of a case necessitating extensive subtotal resection of the small intestine.


Subdiaphragmatic abscess: diagnosis and treatment.


Torsion of the spermatic cord.

Torsion of the spermatic cord.


Drug-induced ulcers of the small bowel causing intestinal obstruction or perforation.


Paresthesias of the lateral femoral cutaneous nerve after pelvic surgery.


Application and proper interpretation of central venous pressure monitoring in the management of shock.


Gallstones, pancreatitis and pregnancy.

Gallstones, pancreatitis and pregnancy.


Constrictive pericarditis: a continuing problem.


The subclavian steal syndrome: clinical experiences.


Abscess of the pancreas: diagnosis and treatment.


Routine sigmoidoscopy.

Routine sigmoidoscopy.


Isolated complete rupture of the pancreas from non-penetrating abdominal trauma, treated by distal pancreatic resection.


Mediastinal teratoma in an infant: surgical removal.


Effect of Noble-Collip drum shock on respiratory control in rat liver and kidney mitochondria.


Surgical significance of the lower esophageal ring.


Acute pancreatitis.

Acute pancreatitis.


An introducer for difficult intubation.

An introducer for difficult intubation.


Quinacrine (Atabrine) in the treatment of neoplastic effusions.


Coombs'-positive hemolytic anemia in Hodgkin's disease.


Necrotizing nocardial pneumonitis.

Necrotizing nocardial pneumonitis.


Psychiatric family consultations. A practical approach in family practice for the personal physician.


Palpable spleens in college freshmen.

Palpable spleens in college freshmen.


Quantitative displacement of acid-base equilibrium in metabolic acidosis.


Plasma volume and renal circulatory function in cirrhosis.


Erythrocytosis and primary aldosteronism.


Traumatic myocardial infarction. Report of a case with normal coronary angiogram.


Acute glomerulonephritis with absence of abnormal urinary findings. Diagnosis by light and electron microscopy.


Sarcoidosis: a case presenting with dysphagia and dysphonia.


Smallpox vaccination. Recommendation of the U. S. Public Health Service Advisory Committee on Immunization practices.


The changing emphasis in clinical research. I. Topics under investigation. An analysis of the submitted abstracts and selected programs at the annual "Atlantic City Meetings" during 1953 through 1965.


The changing emphasis in clinical research. II. Sites and sources of the investigations.


From boardwalk to bedside--clinical research in American Medicine.


The functional significance of the cardiac nerves.


Immunotherapy of Pseudomonas infections.


A model for rheumatic carditis?

A model for rheumatic carditis?


Sugar, fat, and the pill.

Sugar, fat, and the pill.


Malaria in servicemen from Vietnam.

Malaria in servicemen from Vietnam.


Radiothyroxine turnover as a test of thyroid function.


The comparative anatomy and pathology of anal glands. Arris and Gale lecture delivered at the Royal College of Surgeons of England on 25th February 1965.


Methods in training the conscious control of motor units.


Myocoder-computer study of electromyographic patterns.


Sensory conduction studies of median and ulnar nerves.


Rehabilitation of the geriatric amputee: a plea for moderation.


The physiologic effects of ice massage.

The physiologic effects of ice massage.


A functional splint for grasp driven by wrist extension.


Renal artery stenosis with hypertension and high haematocrit.


Depot grass-pollen injections in asthma: effect of repeated treatment on clinical response and measured bronchial sensitivity.


Injuries due to accidental injection of paint from high-pressure paint guns.


Status epilepticus treated by intravenous infusions of thiopentone sodium.


Volvulus of the sigmoid colon among Pathans.


Infectious diseases as a specialty.

Infectious diseases as a specialty.


Increase in the incidence of non-secretors of ABH blood group substances among alcoholic patients.


Carpal tunnel syndrome presenting as a complete median-nerve palsy with trophic changes.


New drugs against tuberculosis.

New drugs against tuberculosis.


Onchocerciasis.

Onchocerciasis.


Family planning in India.

Family planning in India.


Diet and state of nutrition of Pakistani infants in Bradford, Yorkshire.


Facial pain and depression.

Facial pain and depression.


Doctors in the Forces.

Doctors in the Forces.


Fatigue fracture of the femur.

Fatigue fracture of the femur.


Twenty years of abstracts.

Twenty years of abstracts.


New look at the National Health Service.


Hydrotic ectodermal dysplasia--Clouston's family revisited. Several families segregating for hydrotic ectodermal dysplasia are described, including the later generations of a family originally reported by Clouston (1929). No deviations from an autosomal dominant pattern of inheritance were found.


Comprehensive history taking for the non-psychiatrist. To an increasing degree the psychiatrist is oriented to the community and general hospital either as consultant, therapist, or collaborator in overall patient management. In these new roles, he becomes a more comprehensive physician and also conveys psychiatric insights to his colleagues.Psychological factors and the patient's personality "style" influence the development and course of every disease, complicating diagnosis and effective treatment. It is a basic requirement that a good working alliance be established between patient and physician. This is assisted by comprehensive history taking, which clarifies the lifesetting in which the illness began, the patient's personality and his habitual reactions of emotional regression under stress. It will also point up errors introduced by the patient, omissions, and distortions in offering the subjective data which the physician must evaluate.SEVEN MAJOR PERSONALITY TYPES AND APPROPRIATE PHYSICIAN RESPONSES ARE OUTLINED: the dependent demanding oral patient, the orderly controlled obsessive, the dramatic seductive hysteric, the long-suffering masochist, the querulous paranoid, the overbearing narcissist and the aloof withdrawn schizoid.The non-psychiatrist can resolve complex and puzzling medical problems if he has an increased awareness of how emotional forces complicate illness and if he can exploit comprehensive history taking to the full.


The odd Meckel's.

The odd Meckel's.


Cardiac arrhythmia due to persistent bigeminal rhythm in the neonatal period.


Management of the nephrotic syndrome due to primary renal disease.


Determination of uric acid. An adaptation of the Archibald method on the autoanalyzer.


3-methoxy-4-hydroxymandelic acid (vma) by microfiber chromatography.


A review of some important problems concerning lung cancer. The importance of complete preoperative assessment in bronchogenic carcinoma. Part I of this review described the pathogenesis of lung cancer and emphasized that it was largely a preventable disease. In the present paper, attention is drawn to the prevalent but false impression that treatment of established disease is quite in-effective. In eight consecutive series of cases (over 2300 patients) the authors have seen a change in the clinical environment in which lung cancer is treated-from one of discouragement and apathy to one of outspoken encouragement and enthusiasm.Complete preoperative assessment-an evaluation of the biology of the tumour-host relationship as well as technical resectability-avoids unnecessary surgical intervention and stimulates a trend to earlier referral. This has permitted increasing use of resection with a declining mortality and a continuing improvement in overall survival. On the basis of present resectability rates (37.5%) and a 39% five-year survival rate in those who have had curative resection, it is estimated that current over-all five-year salvage should exceed 13%. This is more than a five-fold increase in survival for all patients compared to that achieved by treatment before 1952.


The automated fluorometric determination of serum magnesium. II. Procedure using 8-hydroxyquinoline-5-sulfonic acid.


Microtitration of free fatty acids in plasma.


Kinetic aspects of cyanmethemoglobin formation from carboxyhemoglobin.


Determination of copper and zinc in biological material.


A modified copper method for the estimation of alpha-amino nitrogen in urine.


What is a standard?

What is a standard?


A method for the rapid detection of acute iron toxicity.


Modifications of the automated procedure for blood phenylalanine.


Age variation of iodopyracet and iodide accumulation by the rabbit ciliary body-iris preparation.


On the existence of two separate pools of glucose 6-phosphate in rat diaphragm.


Removal of fatty acids from serum albumin by charcoal treatment.


The comparative enzymology of creatine kinases. I. Isolation and characterization from chicken and rabbit tissues.


The comparative enzymology of creatine kinases. II. Physical and chemical properties.


Evidence for a role of tyrosyl residues in cell membrane permeability.


Studies on the biosynthesis of ergosterol in yeast. Formation of methylated intermediates.


The enzymatic synthesis of wax in liver.


Methylation of ethanolamine phosphatides by microsomes from normal and mutant strains of Neurospora crassa.


Structure and properties of hemoglobin C-Harlem, a human hemoglobin variant with amino acid substitutions in 2 residues of the beta-polypeptide chain.


The tryptic digestion of S-aminoethylated ribonuclease.


The kinetics of glycogen phosphorylases from brain and muscle.


The protein composition of human pancreatic juice.


Glycine metabolism. IV. Effect of borohydride reduction on the pyridoxal phosphate-containing glycine decarboxylase from Peptococcus glycinophilus.


The simultaneous determination of partial specific volumes and molecular weights with microgram quantities.


Studies on the biosynthesis of starch. II. Some properties of the adenosine diphosphate glucose:starch glucosyltransferase bound to the starch granule.


Factors affecting the respiratory control ratio of rabbit heart mitochondria.


Changes in endogenous substrates of isolated rabbit heart mitochondria during storage.


Isolation of an enzyme-coenzyme A intermediate from succinyl coenzyme A-acetoacetate coenzyme A transferase.


The effect of depletion of endogenous substrates on the metabolic behavior of isolated rabbit heart mitochondria.


The synthesis of alpha, beta, and delta peptide chains by reticulocytes from subjects with thalassemia or hemoglobin Lepore.


Studies on the conversion of prothrombin to thrombin: with notes on the cation requirement for this reaction.


The viability and effect of flow upon function of the ex vivo perfused pig liver.


The influence of physical stress and exercise on growth hormone and insulin secretion in man.


Relative potency of arginine-8-vasopressin and lysine-8-vasopressin in humans.


Effects of hypocapnia and hypercapnia on intracellular acid-base equilibrium in man.


A multiplace metabolimeter with a Servo-driven volume meter for use with artificial atmospheres.


The detection of cholinesterase inhibition in erythrocytes of rats fed low levels of the carbamate Banol.


Equipment and techniques for the quantitative recovery of steroids from thin-layer chromatography plates.


Coated charcoal assay of serum calcium fractions.


A nation starts a program: Regional Medical Programs, 1965-1966.


Medical college costs.

Medical college costs.


The study of applicants, 1965-66.

The study of applicants, 1965-66.


A retrospective view of medical specialty choice.


Use of a labor union group in a medical education program.


Student retention of a programmed instrucion course in immunohematology.


On medical school costs and airplanes.

On medical school costs and airplanes.


The review of areas: a simple way to take a comprehensive medical history.


Manpower for tomorrow's health services.


A correlative approach to examinations in microscopic anatomy.


The teaching of social medicine and training in the management of health-care services in Poland.


Undergraduate college in relation to medical school application and enrollment.


Production of melanomas from DMBA-induced "blue nevi" in hairless mice with ultraviolet light.


Recovery of radioactivity of N,N'-2,7-fluorenylenebisacetamide-9-C 14 from rats.


Early effects of N,N'-2,7-fluorenylenebisacetamide on the gastric mucosa of the rat.


Pararenal pseudocyst.

Pararenal pseudocyst.


Erythema multiforme in a premature infant associated with sepsis due to Pseudomonas.


Clinical pharmacology of antimicrobials in premature infants. II. Ampicillin, methicillin, oxacillin, neomycin, and colistin.


Congenital heart disease in adults.

Congenital heart disease in adults.


Use of allopurinol in gout, hyperuricemia and uric acid lithiasis.


Sewing ring healing of cardiac valve prostheses.


Comparative study of cardiac and vascular implants in relation to thrombosis.


Experimental approach to the surgical creation of lymphatic-venous communications.


Sympathectomy in the release of vasoconstriction: similarities of response in cerebral palsy and poliomyelitis.


Success of bypass vein grafts in patients with isolated popliteal artery segments.


A new antithrombotic surface: development and in vitro and in vivo characteristics.


Eversion thromboendarterectomy.

Eversion thromboendarterectomy.


Saphenous vein bypass grafts for femoropopliteal occlusive disease: a reappraisal.


Coronary arteriovenous fistulas: diagnosis and surgical management. Report of fifteen cases.


Surgery for massive myocardial infarction. An experimental study of emergency infarctectomy.


Posterior myocardial revascularization by retrograde internal mammary artery implantation.


Is excision the optimum treatment for all abdominal aortic aneurysms?


Surgical management of tumors of the heart.


Another look at echocardiography. Concepts in biomedical engineering.


Ultrasoundcardiography in mitral valve stenosis.


Symposium on echocardiography (diagnostic ultrasound). Introduction. Echocardiography--Ultrasoundcardiography.


Correlation between ultrasoundcardiography, hemodynamics and surgical findings in mitral stenosis.


Echocardiography. Clinical application in mitral regurgitation.


Echocardiography. Clinical application in combined mitral stenosis and mitral regurgitation.


Pre- and postoperative evaluation of mitral stenosis by ultrasound.


Reflected ultrasound in the diagnosis of tricuspid stenosis.


Ultrasonic engineering in heart diagnosis.


Echocardiography in congenital heart disease. Preliminary observations.


Use of reflected ultrasound in detecting pericardial effusion.


Echoaortography.

Echoaortography.


Clinical application of ultrasound in the analysis of prosthetic ball value function.


Aortic saddle embolus in acute myocardial infarction. Successful removal by a fogarty catheter technic.


John C. Warren on heart failure (1809).

John C. Warren on heart failure (1809).


In-vivo force, frequency, and velocity of dog gastrointestinal contractile activity.


Effect of vascular occlusion on small-bowel intraluminal pressures in dogs.


Experimental studies on the absorption of I-131 triolein in rats.


The effect of dose on d-xylose excretion.


Liver morphology and function tests in obesity and during total starvation.


Unusual liver pathology associated with xanthomatosis and jaundice. Report of a case.


Tropical sprue and intussusception: an unusual association. Report of a case.


Diverticulosis of the colon--fact and speculation.


Letter to the editor.

Letter to the editor.


Studies on homotransplantable lymphomas in hamsters. II. The specificity of the histologic responses in lymphoid tissues and their relationship to metastasis.


Acute ultrastructural effects of 500 roentgens on the lymph node of the mouse.


Congenital segmental coarctation of pulmonary arteries. (An anatomic study).


An electron microscopic study of murine reovirus 3 encephalitis.


Periarterial neurectomy of the hepatic artery. An adjunct to portacaval shunt.


Small bowel blood flow in vivo and in vitro.


Malignant neoplasms of the small bowel.

Malignant neoplasms of the small bowel.


The spectrum of emetogenic injury to the esophagus and stomach.


Changes in body fluid compartments after ileostomy.


Dextran sulfate. A new and potent antiulcer agent.


Effect of colectomy on gastric secretion in dogs.


Peritoneal ammonia levels in acute intra-abdominal disease. A reappraisal.


The asymptomatic patient with gallstones.


Carcinoma of the extrahepatic bile ducts. A clinicopathologic study.


Alterations of in vitro fluid and electrolyte absorption by gastrointestinal hormones.


Recurrence of gastric ulcer after pyloroplasty. A note of warning.


Effect of infusion of hypertonic fluids into the upper intestines on pancreatic secretion.


Clinical and metabolic response to radical distal pancreatectomy for chronic pancreatitis.


Esophageal hiatal hernia. Panel discussion.


Pancreaticogastrostomy.

Pancreaticogastrostomy.


Influence of antibiotic preparation of the bowel on complications after colon resection.


Plasma protein metabolism in patients with acute surgical peritonitis.


Production of duodenal ulcers by exogenous gastrin. An experimental model.


Peptic ulceration and enteritis. A differential diagnosis.


Hemodynamics of experimental acute gastric dilatation.


Ulcers of the pyloric channel.

Ulcers of the pyloric channel.


Gastric mucoproteins in dogs and man. Effects of steroids.


Leiomyosarcoma of the inferior vena cava.


Mortality from ruptured abdominal aortic aneurysm.


Reinforcement of colon anastomoses using polyurethane foam treated with neomycin. An experimental study.


Dry ice refrigeration for above-knee amputations.


Modified Heller procedure to prevent postoperative reflux esophagitis in patients with achalasia.


Acute appendicitis in infants thirty-six months of age or younger. Ten year survey at the Los Angeles County Hospital.


Perforation of the bowel associated with acute appendicitis.


Agenesis of the descending colon with imperforate anus. Correlation with modern concepts of the origin of intestinal atresia.


Duodenocolic fistula with perforation secondary to peptic ulcer.


Chylous ascites associated with malrotation of the intestines.


Postmastectomy lymphangiosarcoma in a patient with carcinoma of the rectum.


Empyema of the gallbladder causing gastroduodenal intramural abscess and pyloric obstruction.


Gastrostomy in postoperative decompression. Indications and methods.


Incidental splenic injury. Is splenectomy always necessary?


Fiber optic sigmoidoscopes. Up-to-date developments.


Fiber optic biopsy forceps.

Fiber optic biopsy forceps.


Some observations on allergy skin testing criticisms.


The case for cytophilic antibodies in cellular immunity.


A preliminary report on the allergenic plants of Ankara.


The antigenic uniqueness of each species of hay fever pollen demonstrated by provocative inhalation.


Is allergy extinct?

Is allergy extinct?


Proof of a genus specific mold allergens.


Treatment of bronchial asthma in children.


Screening for drug toxicity by wave lengths greater than 3,100 A.


Coumarin-induced necrosis of the skin.

Coumarin-induced necrosis of the skin.


Venous anatomy of the sapheno-femoral area.


Cervical thymic cysts.

Cervical thymic cysts.


Unexpected adenomata of the parathyroid.


Gas gangrene of the high-velocity missile wound.


Internal sphincterotomy. An appraisal with special reference to sequelae.


Duodenal and gastric ulceration after burning.


Magnesium deficiency complicating intestinal surgery.


Traumatic intramural haematoma of the duodenum.


Critical evaluation of the assessment of maximal gastric secretion stimulated by histamine.


Resection of squamous-cell carcinoma of the oesophagus with end-to-end oesophageal anastomosis.


Treatment of Mondor's disease.

Treatment of Mondor's disease.


Wandering spleen associated with enlargement of the left kidney.


Fibroma of the duodenum.

Fibroma of the duodenum.


Arterial injuries in an accident unit.

Arterial injuries in an accident unit.


Selective surgery for relapsing pancreatitis.


Prevention of acute renal failure in surgical practice.


Chromosome studies in polyorchidism.

Chromosome studies in polyorchidism.


Observations on the aetiology of pectus excavatum and other chest deformities, and a method of recording them.


Vesico-ureteric reflux after transurethral meatotomy.


Renal function and renal failure in badly burned children.


Early operation for acute haemorrhoids.

Early operation for acute haemorrhoids.


Assessment of vascular integrity of intestinal segments by dye injection.


Caecal diaphragms causing mucocele of the appendix and acute appendicitis.


Submucous lipoma of the stomach presenting as pyloric obstruction.


Gastro-intestinal tuberculosis. A 10-year review.


Afferent limb internal strangulation in obstructed inguinal hernia.


Forward and backward transmission of pressure waves in the pulmonary vascular bed of the dog.


Korotkoff sounds. An experimental critique.


Sequence of atrial depolarization at different stages of development of the chick embryo.


Comparison of the reflexes elicited from combined or separate stimulation of the aortic and carotid chemoreceptors on myocardial contractility, cardiac output and systemic resistance.


Cardiac failure in the dog as a consequence of exogenous hyperthyroidism.


On the cause of ventricular asystole during vagal stimulation.


Effects of nylidrin, isoproterenol and phenoxybenzamine on dogs subjected to hemorrhagic shock.


Sympathetic control of coronary circulation.


Step hypocapnia to separate arterial from tissue PCO2 in the regulation of cerebral blood flow.


The excretion of vanilmandelic acid in the urine of children.


A survey of pregnancy wastage, perinatal mortality and maternal mortality, and a suggestion for a uniform international classification.


A clinical analysis of 10 cases of postoperative infection with Flavobacterium meningosepticum.


Primary hyperlipidaemia and dietetic treatment. Gas-liquid-chromatographic evaluation of the changes in the plasma lipids and their fatty acid pattern in hyperlipidemia following administration of a diet rich in poly-unsaturated lipids.


Intracavitary radium therapy of bladder tumors.


Transseptal catheterization of the left side of the heart. Technique and complications.


Prophylactic preoperative digitalization in old surgical patients.


Extradural spinal cysts. A literature survey and a case of multiple extradural cysts.


An epidemiological study of hospital infection with Flavobacterium meningosepticum.


A female child with five X chromosomes.

A female child with five X chromosomes.


Hematocrit values of capillary blood in the newborn infant.


Gangrene of the foot following intramuscular injection in the lateral thigh: a case report with recommendations for prevention.


Direct current electroshock in the treatment of supraventricular arrhythmias.


Treatment of diabetes insipidus in children with lysine-8-vasopressin.


Passive transfer of delayed hypersensitivity reaction to tuberculin in children with protein calorie malnutrition.


Adrenocortical neoplasms with hemihypertrophy, brain tumors, and other disorders.


Pulmonary aspergillosis in children.

Pulmonary aspergillosis in children.


Conference on treatment of phenylketonuria.


Legislation and advances in knowledge--acceleration or inhibition?


Sites for intramuscular injections.

Sites for intramuscular injections.


Dysgammaglobulinemic antibody deficiency syndrome.


Salmonellosis in infants and children.

Salmonellosis in infants and children.


Eosinophilic meningitis among children in Hawaii.


Failure to detect subtle neurotropism of live, attenuated measles virus vaccine.


The diagnosis of complete extrahepatic obstruction by rose bengal I-131.


Pituitary-adrenal responsiveness after coricosteroid therapy in children with nephrosis.


Tryptic activity of the duodenal juice in aplastic anemia.


Cortisol production rate. VI. Hypoglycemia in the neonatal and postneonatal period, and in association with dwarfism.


The incidence of neonatal hypoglycemia--a completed survey.


Infantile coronary sclerosis with atrioventricular block.


A modified technique for percutaneous needle biopsy of the kidney.


An inborn error of short-chain fatty acid metabolism. The odor-of-sweaty-feet syndrome.


Coarctation of the aorta in infancy. Hemodynamic studies.


The organization and economics of a mobile child welfare team in Sierra Leone.


Liver function tests in the diagnosis of hepatic amoebiasis.


Correlation of clinical, biochemical, radiological, and histological findings in tropical sprue.


Studies in the epidemiology of East African leishmaniasis. 3. Immunity as a determinant of geographical distribution.


The intravenous glucose tolerance test: peripheral disposal of the glucose load in controls and diabetics.


Ethanol-induced hypoglycemia. I. The acute effects of glucose output and peripheral glucose utilization in fasted dogs.


Glucagon-induced hypocalcemia.

Glucagon-induced hypocalcemia.


The effect of D-ribose infusion on serum immuno-reactive insulin and glucose concentration.


The effects of triiodothyronine on some metabolic parameters of obese individuals. Blood C-14-glucose replacement rate, respiratory C-14-O-2, the pentose cycle, the biological half-life of T-3 and the concentration of T-3 in adipose tissue.


Effect of calcium on iodine metabolism in man.


Abnormalities of growth hormone regulation in acute intermittent porphyria.


A study of 136 patients with mesenteric infarction.


Influence of nucleotide derivatives on lipolysis and lipid peroxide formation in vitro.


Esophageal perforations.

Esophageal perforations.


Male breast tumors.

Male breast tumors.


Heparin rebound in open heart surgery.

Heparin rebound in open heart surgery.


Medicare and surgical residency programs.


The effect of epinephrine on arteriovenous shunts in the pathogenesis of shock.


Posterior sphincterotomy in Hirschsprung's disease.


The hazards of popliteal aneurysms.

The hazards of popliteal aneurysms.


The first example of auto-Anti-Xga.

The first example of auto-Anti-Xga.


A simple concentration osmometer and its application to the determination of the oncotic efficiency of plasma substitutes.


A nebulous antibody responsible for cross-matching difficulties (Chido).


ABO blood groups and thyrotoxicosis.

ABO blood groups and thyrotoxicosis.


On the pathogenesis of ABO erythroblastosis: demonstration of quantitative variations in the power of neonatal erythrocytes to combine with antibody, using the immuno-fluorescent technique.


Haptoglobin and Gc types in the Haida Indians.


The foroblique fiberoptic esophagoscope.


Further examples of Jk(a-b-) blood in Hawaii.


Cinégastroscopy with two new gastroscopes.


The fiber duodenoscope: a preliminary report.


The solitary pedunculated colorectal lesion: problems in management.


Hirschsprung's disease--the Duhamel modification.


A multidisciplinary approach to the treatment of alcoholism.


Special clinical problems in day hospitalization.


The twenty-minute hour: an approach to the postgraduate teaching of psychiatry.


The envelope and the psychiatrist: a study of patients' envelopes.


Army psychiatry in the mid-'60s.

Army psychiatry in the mid-'60s.


A psychiatric "back-up" system for selection of space crews.


The Army and the untrained "psychiatrist".


Innovations in military corrections.

Innovations in military corrections.


Between two worlds: Filipinos in the U. S. Navy.


Emotional illness: a dilemma of command.


Military retirement: the retirement syndrome.


The significance of the suicide gesture in the military.


Ocular and cutaneous side effects after prolonged chlorpromazine treatment.


Pancytopenia due to chlorpromazine.

Pancytopenia due to chlorpromazine.


Electroconvulsive treatment of a patient with artificial mitral and aortic valves.


Suicide during an LSD reaction.

Suicide during an LSD reaction.


Drug-induced extrapyramidal symptoms: their incidence and treatment.


Splenic arteriovenous fistula. A case report.


Arterial tone in endotoxin hypotension.

Arterial tone in endotoxin hypotension.


Thoracic aortography in cerebrovascular insufficiency. Report of 250 cases.


Significance of thyroid tissue in lymph nodes associated with carcinoma of the head, neck or lung.


Correlations of international cancer death rates. An epidemiological exercise.


Gastric analysis as a screening measure for cancer of the stomach.


Neurogenic nature of so-called inflammatory fibroid polyps of the stomach.


Erythroleukemic phase of mouse myeloproliferative syndrome.


Trauma and the localization of tumor cells.


Blood flow and oxygenation of tumors in mice. I. Effects of breathing gases containing carbon dioxide at atmospheric pressure.


Blood flow and oxygenation of tumors in mice. II. Effects of vasodilator drugs.


Blood flow and oxygenation of tumors in mice. 3. Effects of breathing amyl nitrite in oxygen on radiosensitivity of the C3H tumor.


Separation of alkaline phosphatase enzymes in human serum using gel-filtration (Sephadex G-200) techniques.


Carcinoma of the uterine cervix. A study of 864 patients.


Cross-circulation experiments on the mechanism of the natriuresis during saline loading in the dog.


Sulfisoxazole levels in the prostatic secretion of dogs after pilocarpine stimulation.


Influence of testosterone on the development of bone marrow at sites of transplanted bladder mucosa.


Acute renal vein ligation in dogs.

Acute renal vein ligation in dogs.


Gold leaf in the treatment of urinary fistulas.


Histamine analog effect on the ureter.

Histamine analog effect on the ureter.


Note on the enzymatic synthesis of deoxyribonucleic acid by human testis.


The developing pattern of clinical pathology.


Clinical and electron microscopic studies of a case of glycolipid lipoidosis (Fabry's disease). A case of glycolipid lipoidosis (Fabry's disease) in a 27-year-old man is recorded. The case is unusual in that despite extensive disease evidenced by widespread skin lesions, ocular abnormalities, and proteinuria, renal function was only minimally impaired. Electron microscope studies of kidney and skin showed that most cells contained the characteristic lipid described in this condition.


Adult Fanconi syndrome with monoclonal abnormality of immunoglobulin light chain. Two adult cases of the Fanconi syndrome are described, in each of which there was abnormal urinary excretion of immunoglobulin kappa-chain. The significance of this finding is discussed in relation to the recognized association between multiple myeloma and the Fanconi syndrome.


Possibility of normokalaemic primary aldosteronism as reflected in the frequency of adrenal cortical adenomas. Adrenal cortical adenomas with diameters greater than 3 mm. were found in 185 (3.61%, of 5,120 consecutive necropsies. A progressively higher incidence with increasing age was noted) 82% of the adenomas occurring in cases in the age range 51-80 years. On the basis of age distribution of adenomas and their connexion with hypertension, there does not seem to be sufficient proof to suppose that the cortical adenomas frequently found at necropsy can be held responsible for causing normokalaemic primary aldosteronism to the extent assumed by Conn (1964).


Blood lipid levels, thyroid status, and glucose tolerance in progressive partial lipodystrophy. Eight women with uncomplicated progressive partial lipodystrophy and two with progressive lipodystrophy and diabetes mellitus were studied. Plasma triglyceride levels were significantly elevated in the subjects with uncomplicated lipodystrophy; serum cholesterol, phospholipid, and plasma free fatty acid levels were normal. Paper electrophoresis showed increases in serum pre-beta lipoprotein and chylomicra. Thyroid function, as measured by radioiodine and stable iodine studies, was normal. Some subjects had a raised basal metabolic rate. Intravenous glucose tolerance was normal in patients with the uncomplicated disease.


Occurrence of various types of penicillinase plasmid among 'hospital' staphylococci. The type of penicillinase plasmid carried by penicillin-resistant cultures of Staphylococcus aureus isolated from eight London hospitals has been determined. Among ;endemic' hospital staphylococci, cultures resistant to mercury salts and producing large amounts of A-type penicillinase, a high proportion of which is extracellular, are most common. C-type penicillinase is rarely associated with resistance to mercury salts.The majority of strains resistant to penicillin and at least one other antibiotic carried the alpha-plasmid. Possible reasons for the prevalence of the alpha-plasmid among endemic hospital staphylococci are discussed.


Use of thiosemicarbazone and para-nitrobenzoic acid in screening tests for anonymous mycobacteria. In screening for anonymous mycobacteria the use of thiosemicarbazone (10mug./ml.) may give rise to false positive results. Although these can usually be overcome by further tests, additional time and effort is required, which seriously limits the value of thiosemicarbazone as a true screening agent. Para-nitrobenzoic acid (500 mug./ml.) has proved more satisfactory in our hands; no false positive results have been obtained and it has the additional advantage that strains of M. kansasii (usually thiosemicarbazone sensitive) are resistant to para-nitrobenzoic acid.


Simple method for estimating plasma hemoglobin during open heart surgery.


Electrophoresis using a constant potential across the separation field.


Squamous differentiation in carcinoma in situ of the cervix uteri. A cyto-histological correlation of malignant intraepithelial lesions with invasive carcinoma. Cervical biopsies from 97 women with malignant cells in cervical scrape smears have been studied. Forty-eight patients had invasive squamous carcinoma, and 49 had intraepithelial lesions. Of these, six had dedifferentiated carcinoma in situ, nine had the differentiated lesions generally known as ;severe dysplasia', and 29 had both; the severity of the dysplasia remained doubtful in five patients. The ;severe dysplasia' was compared with invasive carcinoma. A cellular analysis of the biopsies showed that the two categories have a number of features in common, chiefly the presence of atypical and normal mitoses, nucleoli, horn cells, and giant cells. The stratification of the epithelium in ;severe dysplasia' is invariably abnormal and the architecture closely resembles that of invasive carcinoma. The cells in the smears from ;severe dysplasia' are similar to those in invasive carcinoma. It is suggested on the basis of these observations that a ;severe dysplasia' should be interpreted as a differentiated carcinoma in situ.


Urinary excretion of foreign antigens and RNA following primary and secondary injections of antigens. Two soluble antigens, BSA and KLH labeled with sulfanilate-(35)S, when injected intravenously into normal animals, were excreted in the urine to over 70% in 24 hr. Over the next 6 days, 25% more was excreted after which time only a trace could be detected. Much of the antigen remaining from the primary injection appeared in the urine following a secondary injection of the unlabeled protein carrier at 7 days after primary injection. The antigen material found in the urine was quite heterogeneous with respect to physical properties and much of it was associated with RNA material as shown by chromatographic analyses. The main difference between the labeled material released following the primary and secondary injection was the higher degree of association of antigen material with nucleotide material after secondary injection as compared with primary injection. Further study is needed to distinguish qualitative from quantitative changes of the components, antigen and nucleic acid, and also the nature of their association. Possible similarities were found for the RNA-antigen material released from tissue after secondary injection of unlabeled antigen, and the material that was isolated previously from liver.


In vivo transmission of drug resistance factors between strains of Staphylococcus aureus. 1. Multiply resistant strains of Staphylococcus aureus often harbor one or more extrachromosomal drug resistant factors as well as temperate prophages capable of mediating generalized transduction. 2. Spontaneous transduction occurs in mixed cultures of such staphylococcal strains, and the extrachromosomal resistance factors are involved more frequently than are chromosomal genes. 3. Spontaneous transduction of extrachromosomal determinants of erythromycin resistance and of linked penicillin-erythromycin resistance occurs in the kidneys of mice in which mixed infection has been induced.


Experimental allergic glomerulonephritis induced in the rabbit with homologous renal antigens. Rabbits immunized to several homologous renal antigens developed a variety of autoantikidney antibodies. Some of these antibodies reacted with the host's glomeruli and appeared to cause glomerulonephritis. Passive transfer of sera from some of these nephritic rabbits into normal, unilaterally nephrectomized rabbits led to the induction of nephritis. The production of autoantibody to glomeruli was transitory in most instances in spite of continued immunization. In some rabbits immunized to whole kidney homogenate, extracts or sediment, antibodies were found fixed to renal tubular basement membranes where an ultrastructural lesion was demonstrated. Rabbits also produced antikidney antibody apparently to tubular cytoplasmic components which did not fix to kidney in vivo and were of no pathogenetic significance. Immunization with autologous renal basement membranes induced a small autoantibody response in half the rabbits. This response was not associated with detectable renal injury.


Comparative studies between pathogenesis of street and fixed rabies infection. Comparative neuropathology of Ammon's horn caused by both the street and fixed rabies infection was studied by combined light and electron microscopy. Neurons containing Negri bodies appeared comparatively little damaged. In striking contrast, in the case of fixed virus infection, neurons showed the following variety of degeneration. Lightly damaged neurons showed an increase in the number of small vesicles throughout the cytoplasm. A considerable number of lysosomes were also encountered within these nerve cells. Severe necrotic alteration involving the nucleus as well as the cytoplasm was found in the nerve cell band. The characteristic homogeneous foci (matrices) were discernible within these neurons. It appears that the matrix is morphologically identical with the ground substance of the Negri body, though its size is smaller than that of the Negri body. This evidence suggests a possibility that fixed virus injures neurons so extensively that they cannot bring about the full development of the characteristic matrix of the Negri body recognizable by the light microscope. Selective vulnerability was demonstrated among different groups of neurons in respect of cytopathogenesis of both street and fixed virus infection.


The regulation of pinocytosis in mouse macrophages. 3. The induction of vesicle formation by nucleosides and nucleotides. A study has been conducted on the influence of nucleosides and nucleotides to induce the formation of pinocytic vesicles in cultured mouse macrophages. Extremely high levels of cytoplasmic vesicles were found after exposure of macrophages to adenosine 5'-phosphate, ADP, and ATP. A limited vesicle response was obtained with adenosine 2'-. and 3'-phosphate, 3',5'-adenosine-phosphate, and deoxyadenosine 5'-phosphate. The di- and triphosphates of guanosine, inosine, cytidine, and uridine were stimulatory but much less active than the adenosine derivatives. Adenosine administration resulted in high levels of pinocytic activity whereas other nucleosides, including inosine, guanosine, cytidine, and uridine, yielded little or no stimulatory effect. Adenosine and its 5'-phosphates produced morphological effects on macrophages characterized by increased spreading, a thin, peripheral cytoplasmic veil with denser cores of oriented mitochondria and contraction of the centre-sphere region. Large numbers of pinosomes were seen in association with mitochondria-containing portions of the cytoplasm. The stimulatory effects of adenosine and ATP were rapid and involved the majority of cells in the culture. Adenosine was unable to reverse the pinocytosis inhibition produced by 2,4-DNP, whereas ATP raised vesicle counts to high levels. Possible mechanisms for these effects are discussed.


Adjuvators to the propagation of mouse mammary tumor cells on expanses of subcutaneous tissue. The cells of a mouse mammary cancer were obtained with enzymes in suspensions which could be filtered to exclude all which were not single and most which were already dead. Heavy suspensions of these individual cells were plated over the dorsal subcutaneous expanses of female weanling mice where they implanted and grew to form coalescent tumors covering the back more or less entirely. Sparser suspensions, similarly plated (a) gave rise to fewer tumors, and (b) gave rise to tumors reaching measurable size later. These two consequences of sparser plating left room for the testing of adjuvators to transplantation. Adjuvator effects were obtained by splitting the subcutaneous expanses beforehand and by injecting liver along with the plated cells. Through 28 plated generations over 4 yr the tumor maintained completely stable, morphological heterogeneity. These findings with a complex tumor indicate strongly that its heterogeneity comes not from repeated cellular mutation late in its development, but from diverse potentiality to give rise to cells of specific and differing character, inherent in its individual cells at the time of its multicellular origin.


Experimental transmission of influenza virus infection in mice. IV. Relationship of transmissibility of different strains of virus and recovery of airborne virus in the environment of infector mice. A mouse-adapted Jap. 305 strain of influenza A(2) virus was found to be much more readily transmitted from one mouse to another than the NWS strain of influenza A(0) virus although the two viruses were equally pathogenic for mice as judged by pulmonary virus titers and lung lesions. The survival of artificially created aerosols of virus and the quantity of airborne virus required to initiate infection in mice were identical for the two viruses. The difference in transmissibility was associated with the recovery of infectious airborne virus in the environment of mice infected with the Jap. 305 strain during the period of their maximum infectiousness, but not in the environment of mice infected with the NWS strain.


Experimental transmission of influenza virus infection in mice. 3. Differing effects of immunity induced by infection and by inactivated influenza virus vaccine on transmission of infection. Immunization of mice by infection or intraperitoneal injection with homotypic A(2), heterotypic A(0), or recombinant A(0)A(2) virus have differing effects on transmission of influenza A(2) virus infection. Immunization by infection with A(2) virus resulted in refractoriness to reinfection either by artificial aerosols or by exposure to infected cage-mates. Immunization by inoculation with inactivated A(2) virus vaccine resulted in a decreased susceptibility to transmitted infection in immunized contacts, but following A(2) virus challenge, transmission of infection by immunized infectors was not altered. Immunization by infection with influenza A(0) virus or recombinant A(0)A(2) virus resulted in a decreased susceptibility to transmitted A(2) virus infection in immunized contacts, and to decreased transmission after A(2) virus infection in immunized infector mice. These differing effects on transmission of infection are attributed to differences in specific local immunologic responses following the various immunization procedures.


Keratoconjunctivitis sicca and new techniques in its management.


Lactose maldigestion in Australian Aboriginal children.


Acute infections of the lower part of the respiratory tract in Papuan infants and children.


Heat sterilization of the circle absorption unit: unit designed to withstand autoclaving.


Road trauma: causes and prevention. The night road scene.


Road safety on the snowy mountains scheme and its application to the community.


The immediate weight-bearing prosthesis.


Bowler's cramp.

Bowler's cramp.


Improvised equipment for civil defence.

Improvised equipment for civil defence.


Cytogenetic studies in megakaryocytic myelosis.


Breast feeding.

Breast feeding.


The trigonal canal.

The trigonal canal.


Roentgen evaluation of distal urethral obstruction.


Selective angiography in arteritis of the aorta and its major branches.


Renal hamartoma (angiomyolipoma). Its angiographic appearance and response to intra-arterial epinephrine.


Petechiae following angiography: evidence for increased capillary permeability.


The angiographic appearance of intracranial sarcomas.


The sellar-cranial index.

The sellar-cranial index.


Superficial temporal artery aneurysms.

Superficial temporal artery aneurysms.


Brachial plexus injury following axillary artery puncture. Further comments on management.


The straight-back syndrome: radiographic manifestations.


Portal vein gas due to administration of fluids via the umbilical vein.


Lymphography in lymphoma: with particular reference to Hodgkin's disease.


Retreatment of brain tumors.

Retreatment of brain tumors.


Hypothyroidism after external irradiation to the thyroid region.


The correlation of clearance and distribution of colloidal gold in the liver as an index of hepatic cirrhosis.


Liver regeneration following hepatectomy, evaluated by scintillation scanning.


Information content of data-blended and conventional photoscans.


Radiation sensitivity in diabetes: preliminary studies with the alloxan diabetic rat.


Evaluation of therapy in chronic lymphocytic leukemia using in vitro lymphocyte transformation.


Experimental reflux pancreatography and cholangiography.


Simultaneous presentation echoencephalography.


Lymphatic cannulation without dye.

Lymphatic cannulation without dye.


Blended scintiscans of lungs with a dual detector system.


A single-film technic for determining the co-ordinates of radiation sources in implant dosimetry.


The problems of long-term pacing of the heart.


An easy method to insure constant monitoring of radiation exposure.


Psychiatry and religion.

Psychiatry and religion.


Acute glomerulonephritis due to skin disease, with special reference to scabies.


Ectopia cordis. Report of a case with attempted operative correction.


A useful anaesthetic circuit.

A useful anaesthetic circuit.


A qualitative test for alcohol in urine.


Human echo perception.

Human echo perception. It has been shown that human test subjects have the ability, under controlled laboratory conditions, to use echoes to detect the presence or absence of targets placed before them. In addition, blind and sighted persons have been able to detect a target monaurally, to make simple shape discriminations, and to locate a target in space. Signal, environmental, and individual variability affect performance in a measurable fashion. This research is an initial step in measuring the limits of a human being's ability to use echoes as a source of information about his physical surroundings. At this point it seems unlikely that the unaided human ear can rival the bat's auditory system for echo perception. It may be, however, that modern technology can partially bridge the evolutionary gap and bring more useful echoes to man's ear than those it now receives. Such an accomplishment would allow us to examine the extent to which man might benefit from this means of sensing his environment.


Tetrahymena: effect of freezing and subsequent thawing on breeding performance. Tetrahymena pyriformis, syngen 1, frozen in 10 percent dimethyl sulfoxide, stored for 2 months, and then thawed could conjugate normally. More significantly, they were viable, in normal numbers, through two sex ual reorganizations. The strains ap parently did not sustain genetic dam age during the treatment. The tech niques offer considerable promise for the maintenance of breeding stocks in ciliated protozoans.


Zinc retention in rabbits: effect of previous diet. The retention of orally administered zinc-65 was influenced by the previous diet. Zinc-deficient rabbits fed a diet containing 25 parts of zinc per million incorporated naturally in soybean protein still retained 58 percent of an oral dose of zinc-65 16 days after the dose was given, while rabbits fed the same diet supplemented with zinc (54 parts per million) as zinc oxide retained only 14 percent. The weight gain and the appearance of the animals fed these two diets were different.


Protein subunits: a table.

Protein subunits: a table.


Visual adaptation to gradual change of intensity. The eye can adapt to the rate of change of brightness. After exposure of the eye to a light that grows gradually brighter, a steady light appears to grow gradually dimmer, and vice versa. A field containing shading gives larger after effects than a spatially uniform field.


Conditioning with delayed vitamin injections. Rats deficient in thiamine were allowed to drink saccharin-fla vored water. They were then given an injection of thiamine which caused their intake of the nonnutritive fluid to increase. Delay of the intramuscular injection up to 30 minutes had no effect upon the acquisition of this condi tioning. Presumably, this delay reflects specialization in the central integrative mechanisms which serve these afferent modalities.


Brain stem structures responsible for the electroencephalographic patterns of desynchronized sheep. Contrary to the results of transecting one half of the rostral pons, unilateral partial lesions of the rostral pons, involving either "specific" or "aspecific" structures, do not prevent the appearance of the desynchronized electroencephalographic patterns of deep sleep in the ipsilateral hemi sphere in cats. This effect, however, is obtained by lesions of the medial as well as lateral tegmental structures of the midbrain. These findings seem to indicate that (i) there is not a single pontine structure or group of structures of crucial importance for the EEG desynchronization of deep sleep; the whole rostral pons appears to contrib ute to the EEG-desynchronizing influ ence; (ii) this influence runs rostrally through the midbrain tegmentum, without following any known fiber pathway.


Circulatory changes in acute pancreatitis.


Role of vagotomy and gastric drainage in the surgical treatment of duodenal ulcer. Results of a ten-year experience at the University of Chicago hospitals.


Hyperbaric oxygenation in the management of gas gangrene.


Arterial infusion chemotherapy for locally advanced cancer.


The subaxillary incision for radical mastectomy.


Active bleeding duodenal ulcer. Management during ten-year period.


Whole organ preservation for transplantation.


Physiologic monitoring of cardiac and critically ill surgical patients.


Gastroesophageal decongestion and splenectomy in the treatment of esophageal varices in bilharzial cirrhosis: further studies with a report on 355 operations.


Iatrogenic pulmonary edema in surgical patients.


Gastric sump drainage with a water seal monitor.


An efficient low negative pressure suction drainage unit.


A new underwater suction drainage unit.

A new underwater suction drainage unit.


Prolonged survivals after partial hepatectomies and second-look procedures for primary and secondary carcinoma of the liver.


Altered lymphatic dynamics following groin and axillary dissection: its relationship to treatment policies for malignant melanoma.


Massive gangrene of the colon due to distal obstruction.


Selective surgical intervention for stab wounds of the abdomen.


The use of various metal sutures to increase tensile strength of wounds.


Acute appendicitis occurring in hernias: a report of 10 cases.


Comparison of renal oxygen consumption and blood flow with cooling and rewarming.


The disposable bubble oxygenator. II. Evaluation of an improved model.


Effect of head-down position during hypotension: studies of head-down tilt and norepinephrine on flow in the internal carotid artery of primates.


Multiple polyposis in children: a review and a report of a case in a 6-year-old child who had associated nephrosis and asthma.


The role of various abdominal surfaces in the absorption of toxic strangulation fluid.


Recurrent eosinophilic infiltrate (granuloma) of the ileum causing intussusception in a two-year-old child.


Combined treatment of omphalocele.

Combined treatment of omphalocele.


Neonatal peritonitis.

Neonatal peritonitis.


Accurate central venous pressure monitoring.


Gastrostomy with a prosthesis.

Gastrostomy with a prosthesis.


Surgical reconstruction of the diseased esophagus. I. Interposition of the jejunum.


Animadversions on pleura and lung.

Animadversions on pleura and lung.


Studies in sarcoidosis. 3. Serum proteins in cases with concomitant erythema nodosum.


Hereditary periodic oedema.

Hereditary periodic oedema.


On the familiar incidence of idiopathic sprue and the significance of pregnancy and partial gastrectomy for the manifestation of the symptoms. Preliminary report.


The long-term prognosis of acute glomerulonephritis. A follow-up study.


The origin of the innocent "vibratory" murmur studied with intracardiac phonocardiography.


Adrenergic beta-blockade and electrocardiographical ST-T changes.


A case of myeloma with flaming plasma cells but no significant M-compound in serum or urine.


The duration of the action of some oral hypoglycemic agents in healthy human subjects.


The effect of dietary fat on whole-blood and plasma viscosity in normal and hypercholesterolemic subjects.


Chromosome studies in acute leukaemia. Evidence for chromosomal abnormalities common to erythroblasts and leukaemic white cells.


The diagnosis essential hypertension.

The diagnosis essential hypertension.


Intracavitary electrocardiography in the diagnosis of arrhythmias.


Screening procedures for hyperglyceridemia. Evaluation of relations between nephelometry (light scattering), optical density (light extinction), serum triglyceride and serum cholesterol.


A case of fatal nialamid poisoning.

A case of fatal nialamid poisoning.


The incidence of acute rheumatic fever in Swedish children 1952-1961. A survey from four hospitals.


Plasma lipids in recurrent jaundice of pregnancy.


Vasopressin as an aid in locating the kidney in roentgen television for renal biopsy.


Fatty acid composition of human adipose tissue related to age, sex, and race.


The kinetics of amino acid absorption and alteration of plasma composition of free amino acids after intestinal perfusion of amino acid mixtures.


Studies on physiology of nutrition in Surinam. XI. The skeleton of aged people in Surinam.


Estimation of red blood cell thiamine concentration from whole blood and serum thiamine by adjustment for hematocrit.


The application of social science research methods to the study of food habits and food consumption in an industrializing area.


Plasma amino acid levels in subjects fed isonitrogenous diets containing different proportions of fat and carbohydrate.


Vagus: nerve of the heart.

Vagus: nerve of the heart.


Individual trends in the total serum cholesterol of children and adolescents over a ten-year period.


Use of an oral diuretic (Doburil) in treatment of bromide intoxication.


Betting odds in medical diagnosis.

Betting odds in medical diagnosis.


Computer diagnosis of thyroid diseases. Comparison of incidence data and considerations on the problem of data-collection.


Relationships between steatorrhea and an insufficiency of pancreatic secretion in the duodenum in patients with chronic pancreatitis.


Intra-articular steroid therapy: repeated use in patients with chronic arthritis.


Electrocardiographic patterns of procaine amide cardiotoxicity.


Platelet adhesiveness and aggregation with chlorophenoxyisobutyric ester.


Coagulation properties of human thoracic duct lymph.


Thrombosis in the dog produced by single rapid infusions of long chain saturated fatty acids.


Nonthrombogenic effect of chronic slow infusions of long chain saturated fatty acids.


The active length-tension relationship in human uterine muscle.


Photoplethysmographic study of the vaginal blood pulse.


Endometrial histology and clinical symptoms following prolonged retention of uterine contraceptive devices.


A program in mass family planning for the urban indigent in a charity hospital.


Lymphocyte transformation in response to phytohemagglutinin during and following a pregnancy.


The immunologic problem of pregnancy. II. Ultrastructure of isogeneic and allogeneic trophoblastic transplants.


Derivation and ultrastructure of the so-called Hofbauer cell.


Influence of phenelzine on 5-hydroxytryptamine level in rat placenta and fetuses.


Plasma free fatty acids and glucose concentrations in the human fetus and newborn exposed to various environmental conditions.


Double pregnancy in a uterus duplex unicollis.


Pregnancy and delivery after ureterosigmoidostomy.


Pulmonary histoplasmosis in a farm family--fifteen years later.


Changes in pulmonary function before and after pneumonectomy for pulmonary tuberculosis.


Histogenesis of tuberculous pulmonary lesions. A study of reticulum patterns.


A study of healing and repair of pulmonary tuberculous lesions with and without chemotherapy.


Sarcoidosis: relationship between changes in lung structure and function.


Pulmonary diffusing capacity and its evaluation by scintillation scanning of the lungs in lung cancer.


Response of leukocytes in culture from tuberculous patients and vaccinated subjects.


Respiratory gas exchange at rest and during exercise in normal and asthmatic children.


Oxygen-induced hypoventilation.

Oxygen-induced hypoventilation.


Molecular characterization of the antibody response in rabbits to intravenously injected BCG.


Cigarette smoke and surfactant.

Cigarette smoke and surfactant.


Sarcoidosis among the Chinese and a review of the worldwide epidemiology of sarcoidosis.


Pulmonary alveolar proteinosis.

Pulmonary alveolar proteinosis.


Primary pulmonary coccidioidomycosis with recovery of the fungus from the stool.


Liposarcoma of the pleura: report of a case. With a review of literature and views on histogenesis.


Group therapy with alcoholic tuberculous patients.


Skin-testing and precipitation antigens from Aspergillus fumigatus for diagnosis of aspergillosis.


Microscopic characteristics of the cutaneous reaction to coccidioidin in humans.


Differentiation of mycobacteria by ultilization of nitrogen compounds as simultaneous nitrogen and carbon sources.


Principles of respiratory care. I. Indications and organization. A statement by the Committee on Therapy. American Thoracic Society.


Principles of respiratory care. 3. Safety and avoidance of complications. A statement by the Committee on Therapy. American Thoracic Society.


Control of morning stiffness in rheumatoid arthritis by high salicylate dosage. Preliminary report.


The biomechanical properties of tendon in relation to muscular strength.


Extradural corticosteroid infiltration. A follow-up study of 50 cases.


Incidence of "rheumatoid factors" in aged serum.


Ultrastructure of normal rat synovial membrane.


Intracytoplasmic filaments in the cells of adult human articular cartilage.


Carpal tunnel syndrome as a manifestation of systemic disease.


Relationship of increased oxygen consumption to catecholamine excretion in thermal burns.


Respiratory burns: a correlation of clinical and laboratory results.


Rate of chondroitin sulfate formation in wound healing.


Role of suture materials in the development of wound infection.