Observations of neuropathic (Charcot) joints occurring in diabetes mellitus.


A comparison of foot forms among the non-shoe and shoe-wearing Chinese population.


De Quervain's disease; a clinical and anatomical study.


Tendon transfers to restore function of hands in tetraplegia, especially after fracture-dislocation of the sixth cervical vertebra on the seventh.


Histochemical studies on glycogen in normal ossification and calcification.


Fracture healing in rats treated with aminoacetonitrile.


The effect of pressor and depressor drugs on intramedullary bone-marrow pressure.


The extra-osseous and intra-osseous blood supply of the talus.


Minerals, collagen, and hexosamine in rat femora.


Sequelae of experimental dislocation of a weight-bearing ball- and socket joint in a young growing animal; gross alterations in bone and cartilage.


Recurrent locking of an index finger.

Recurrent locking of an index finger.


Malignant giant-cell tumor of the ulna; report of a case of eighteen years' duration.


Chondrosarcoma of the small bones of the hand.


A goniometer designed for the hand.

A goniometer designed for the hand.


Bilateral recurrent dislocations of the superior tibiofibular joint with peroneal-nerve palsy.


Recurrent calcified leiomyoma of the pelvis and gluteal regions complicated by pregnancy; a case report.


Anterosposterior projection of the carpometacarpal joint of the thumb by radial shift of the carpal tunnel view.


Anterior-angled plates for high femoral osteotomies.


A follow-up study of the initial group of cases of skeletal tuberculosis treated with streptomycin, 1946-1948; the United States Veterans Administration and Armed Forces cooperative studies of tuberculosis.


The Boston Orthopedic Institution.

The Boston Orthopedic Institution.


A review and analysis of 11,000 fractures seen in a private practice of orthopaedic surgery, 1937-1956.


I. WILLIAM NACHLAS, 1894-1958.

I. WILLIAM NACHLAS, 1894-1958.


ROBERT A. KNIGHT, 1914-1958.

ROBERT A. KNIGHT, 1914-1958.


HENRY FRANZ ULLRICH, 1903-1958.

HENRY FRANZ ULLRICH, 1903-1958.


Descriptive epidemiology of selected neurologic and myopathic disorders with particular reference to a survey in Rochester, Minnesota.


Cerebrovascular diseases: pathophysiology, diagnosis, and treatment.


Multiple sclerosis.

Multiple sclerosis.


Parkinson's disease.

Parkinson's disease.


Epilepsy.

Epilepsy.


Muscular dystrophies, polymyositis, and other myopathies.


A study of the adrenal status in hypertension.


Myasthenia gravis: current status of pathogenesis, clinical manifestations, and management.


The incidence of psychogenic fever in a university hospital.


The L. E. phenomenon and systemic lupus erythematosus.


Effect of a patient-cycled breathing aid on ventilatory efficiency in pulmonary emphysema and poliomyelitis.


The epidemiologic method in cancer research.


The effect of a new bronchodilator aerosol on the air flow dynamics of the maximal voluntary cough of patients with bronchial asthma and pulmonary emphysema.


Intra-articular injections of hydrocortisone prednisolone, and their tertiary-butylacetate derivatives in patients with rheumatoid arthritis and osteoarthritis.


A comparison of the analgesic efficacy of d-propoxyphene (darvon) and meperidine (demerol).


Metabolism of 4-C14-testosterone in human subjects. III. Fate of androsterone and etiocholanolone.


The thermogenic effect and metabolic fate of etiocholanolone in man.


Studies on the biologic characterization of human gonadotropins. II. Comparison of human pituitary gonadotropin (urine) and human chorionic gonadotropin (urine).


Depression of serum and urinary citric acid levels by 17-hydroxycorticosteroids.


The secretion and disposition of cortisol during pregnancy.


Effect of fluorine on thyroidal iodine metabolism in hyperthyroidism.


Effects of hypo- and hyperthyroidism on the filterability of serum magnesium.


Collaborative assays of two urinary preparations of human pituitary gonadotropin.


Androgenic pattern of serum lipids and lipoproteins in response to chorionic gonadotropin in male hypogonadism.


Prolonged turnover rate of hydrocortisone in the newborn infant.


Osteoporosis in hyperadrenocorticism.

Osteoporosis in hyperadrenocorticism.


Histologic evidence of malignancy in a thyroid gland bearing a hot nodule.


Renal concentrating ability in thyrotoxicosis.


Complications during administration of methylestrenolone.


The role of the adrenal cortex in the normal adaptation to dietary sodium deprivation.


The significance of the secretion of aldosterone during dietary sodium deprivation in normal subjects.


Divergence in magnesium, sodium and potassium excretion during stimulation of endogenous aldosterone production.


The urinary excretion of interstitial-cell and follicle-stimulating hormone activity during the normal menstrual cycle.


The urinary excretion of interstitial-cell and follicle-stimulating hormone activity by women with diseases of the reproductive system.


The quantitative determination of progesterone and pregnanediol in human plasma.


Studies on the biologic characterization of human gonadotropins. III. Comparison with sheep follicle-stimulating hormone.


Inhibition of the sodium-retaining influence of aldosterone by progesterone.


Radiocalcium studies of bone formation rate in human metabolic bone disease.


A simplified method for the routine measurement of urinary estroil.


Estrogen excretion in ovariectomized women receiving adrenocorticotropin.


The urinary excretion of tetrahydrocortisol, 3 alpha-allotetrahydrocortisol and tetrahydrocortisone in young and elderly men and women.


The influence of tranquilizing drugs on results of thyroid function studies.


Effect of norethandrolone on serum enzyme levels.


Hypertrophic osteoarthropathy and pretibial myxedema associated with Graves' disease.


The loss of fluid and protein from the blood during a systemic rise of venous pressure produced by repeated valsalva maneuvers in man.


The effect of thiamine deficiency on human erythrocyte metabolism.


Effect of inosine on red cell preservation.


Somatic therapy in psychiatry.

Somatic therapy in psychiatry.


A critical study of promazine therapy.

A critical study of promazine therapy.


An analysis of homicide-suicide.

An analysis of homicide-suicide.


The impact of somatic therapies on course and clinical profile of the schizophrenias.


The personality reaction to adrenalin and histamine.


The serum trihydroxy-dihydroxy bile acid ratio in liver and biliary tract disease.


The metabolism of albumin-bound C14-labeled unesterified fatty acids in normal human subjects.


The inhibition of a conditioned response following arecoline administration in man.


Perfusion studies of the human placenta. I. Effect of estradiol and human chorionic gonadotropin on citric acid metabolism.


Changes in transmural central venous pressure in man during hyperventilation.


Steroid formation by adrenal tissue from hypertensives.


Relationship between the age of human erythrocytes and their osmotic resistance: a basis for separating young and old erythrocytes.


Lipolytic action of corticotropin on rat adipose tissue in vitro.


Response of normal subjects to large amounts of aldosterone.


Quantitative measurement of hematopoietic cells of the marrow.


Quantitative measurement of the erythrocytic and granulocytic cells of the marrow and blood.


The role of anaerobic metabolism in the performance of mild muscular work. I. Relationship to oxygen consumption and cardiac output, and the effect of congestive heart failure.


The role of anaerobic metabolism in the performance of mild muscular work. II. The effect of asymptomatic heart disease.


Studies of thyroid function and the peripheral metabolism of I 131-labeled thyroxine in patients with treated Graves disease.


Ammonia excretion and renal enzymatic adaptation in human subjects, as disclosed by administration of precursor amino acids.


The extinction of avoidance responses under curare.


Pantothenic acid deficiency in man.

Pantothenic acid deficiency in man.


Effect of differential light adaptation of the two eyes on the phosphene threshold.


Effect of lysergic acid diethylamide (LSD-25) on the absolute visual threshold.


Changes in muscle action potentials during prolonged work.


The effect of long-continued, low-intensity gamma irradiation on learning and body weight in the rat.


Mechanism of postoperative limitation in sodium excretion: the role of extracellular fluid volume and of adrenal cortical activity.


Total nondialyzable solids (TNDS) in human urine. II. A method for reproducible fractionation.


Activity and emotionality in pre- and neonatally x-irradiated rats.


The role of stimulation in spontaneous reorganization of visual habits.


Cutaneous sensitivity to electrical pulse stimuli.


Characteristics of food-carrying behavior in the rat.


A comparison of stimulus-presentation procedures in taste-preference experiments.


The effect of varying periods of confinement on activity in tilt cages.


An osmotic factor in the regulation of food in-take in the rat.


Light onset and light offset as reinforcers for the albino rat.


Imprinting and associative learning: the stability of the following response in Peking ducks (Anas platyrhynchus).


The effect of prolonged exposure to visual patterns on learning to discriminate similar and different patterns.


The interaction between form pre-exposure and test requirements in determining form discrimination.


Transposition away from a rewarded stimulus card to a non-rewarded one as a function of a shift in background.


The interval between training and test trials as a determiner of the slope of generalization gradients.


The role of overlearning and drive level in reversal learning.


Primary stimulus generalization as a function of acquisition level in the cat.


Reward and non-reward in the discrimination learning of imbeciles.


Acquisition of a learning set by normal and mentally retarded children.


Comparison of place and response learning in a simultaneous-successive discrimination-learning situation.


Discrimination of concentric-ring patterns by monkeys.


Some factors affecting habit strength in aversive training.


Bar-holding as a preparatory response in escape-from-shock training.


Secondary reinforcement and multiple drive reduction.


Spontaneous recovery following nonresponse extinction.


The intraocular lesions of hog cholera.

The intraocular lesions of hog cholera.


Studies on the heterophile antibodies associated with helminth infections. III. Heterophile antibody in Oesophagostomum dentatum infection in pigs.


Studies on Escherichia coli of animal origin. II. Escherichia coli from young lambs.


Observations on experimental parasitic bronchitis in calves and the response to diethylcarbamazine.


A comparative study of the incidence of vacuolated neurones in the medulla from apparently healthy sheep of various breeds.


Experimental transmission of Avian osteopetrosis.


Immunity against Brucella infection in guinea pigs produced by three different vaccines.


The histopathology of the brain stem of sheep affected with experimental scrapie.


The pathology of experimental staphylococcal mastitis in the goat.


Experimental infections of Pasteurella haemolytica in mice and their use in demonstrating passive immunity.


Relationship between certain personality variables and continuation in psychotherapy.


A case of folie à deux and projective techniques.


The social desirability factor in Edward's PPS.


Self acceptance and marital happiness.

Self acceptance and marital happiness.


Six measures of self-concept discrepancy and instability: their interrelations, reliability, and relations to other personality measures.


Differentiation of clinical groups using canonical varieties.


A comparative analysis of deviant Rorschach response characteristics.


Rorschach concept evaluation test as a diagnostic tool.


Movement responses and creativity.

Movement responses and creativity.


The Yacorzynski block technique: a crossvalidation study.


Approaches to reliability of projective tests with special reference to the Blacky pictures test.


The prognostic significance of certain behavioral variables.


Learning in aphasic patients.

Learning in aphasic patients.


Personality correlates of Q-L differentials on the ACE.


Wechsler-Bellevue scatter as an index of schizophrenia.


Validity of the Hewson ratios: investigation of a fundamental methodological consideration.


Brain injury and intellectual performance.


Identification of item factor patterns within the manifest anxiety scale.


The clinical usefulness of the Archimedes spiral in the diagnosis of organic brain damage.


Intelligence in childhood schizophrenics, other emotionally disturbed children, and their mothers.


Some personality correlates of subjects who fail to appear for experimental appointments.


Normative data and factor analysis on the Parental Attitude Research Instrument.


A self-scored projective measure of achievement and affiliation motivation.


Asynchronism and apparent movement thresholds in brain-injured children.


Opinions of psychologists and psychiatrists about mental health problems.


The weighted Q sort: a procedure for quantitatively estimating emotional disturbance and personality change.


Some social-psychological characteristics of a child guidance clinic caseload.


Adjustment and prediction of others' behavior.


Nonprojective determinants of perception on the TAT.


Age and sex influences on MMPI profile peak distributions in an abnormal population.


The validity of the objective Rorschach and the MMPI.


Spearman correlations between MMPI scores of college students and their parents.


The MMPI in cerebral palsy.

The MMPI in cerebral palsy.


An evaluation of the comparability and reliabilities of two behavior rating scales for mental patients.


The relation of difficulty in drawing to ratings of adjustment based on human figure drawings.


On the relationship between manifest anxiety and intelligence.


Anxiety: unitas or multiplex?

Anxiety: unitas or multiplex?


Test anxiety questionnaires.

Test anxiety questionnaires.


Allergy and the need for recognition.

Allergy and the need for recognition.


Chance frequency in matching problems when success or failure is reported after each matching operation.


An unprofitable application of the semantic differential.


Varieties of response sets.

Varieties of response sets.


Further evaluation of the Archimedes spiral aftereffect.


The spiral aftereffect in a neurological setting.


A further study of the perception of apparent motion by schizophrenics.


Success and failure in client-centered therapy as a function of client personality variables.


The performance of psychoanalytic and client-centered therapists in an initial interview.


A theoretical framework for nondirective play therapy: concepts from psychoanalysis and learning theory.


Personality patterns of patients before and after application for psychotherapy.


The diagnostic validity of the Ames danger signals.


Vocabulary as a basis for estimating intelligence from the Rorschach.


An investigation of determinants inducing individuals to seek personal counseling.


Extraversion, neuroticism, radicalism, and tendermindedness.


Handwriting conventions as determinants of human figure drawings.


The relationship between Edwards' and McClelland's measures of achievement motivation.


Second-order factors in personality measurement.


The MMPI performance of veterans with organic and psychiatric disabilities.


Two new experimental scales of the MMPI.


The parental attitudes of mothers of schizophrenics.


Experience of clinicians, and speech characteristics and statements of clients as variables in clinical judgment.


Representative elements in role construct technique.


The Taylor A scale and clinical measures of anxiety.


A note on the reliability of the Leiter International Performance Scale, 1948 revision.


Success and failure in client-centered therapy as a function of initial in-therapy behavior.


The prediction of length of stay in psychotherapy.


Suggestibility and dependency.

Suggestibility and dependency.


Some psychological correlates of field independence.


Psychoanalysts as expert observers of the therapy process.


An analysis of patient-therapist compatibility.


The relationship of stimulus ambiguity on the TAT to the productivity of themes.


Countertransference effects in psychotherapy.


Social desirability and self-ratings of intakes, patients in treatment, and controls.


A technique for investigating the relationship between the behavior cues of the examiner and the verbal behavior of the patient.


Q-L variability, MMPI responses, and college males.


Some scale and test correlates of a personality rigidity scale.


The effect of cultural factors on the relationship between personality, intelligence, and ethnocentric attitudes.


A note on the behavioral validity of the Gordon personal profile.


The effects of chlorpromazine on learning in chronic psychotics.


Stylus maze performance of chronic schizophrenics taking chlorpromazine.


The effect of differential motivating instructions on the emotional tone and outcome of TAT stories.


Signs of homosexuality in human-figure drawings.


Deviant responses as indicators of immaturity and schizophrenia.


An evaluation of human-figure drawing indicators of paranoid pathology.


Sex differences on the Rorschach.

Sex differences on the Rorschach.


Causative factors in the production of rotations on the Bender-Gestalt designs.


Dental papilla in tissue culture.

Dental papilla in tissue culture.


In vitro chemical and bacterial changes in saliva.


The glyoxylic reactant in saliva.

The glyoxylic reactant in saliva.


The influence of sialoadenectomy in rats on food and water consumption.


Film thickness as a limiting factor on the ability of various chemicals to inhibit glycolysis in salivary sediment.


Effect of certain restorative materials on solubility of dentin.


The effect of residual stress and water change on the deformation of hydrocolloid impression materials.


Studies on salivariadenectomized Hunt-Hoppert caries-resistant and caries-susceptible rats. I. Effect of salivariadenectomy on dental caries and several groups of the oral microflora.


The effect of feeding calcium phosphate salts with different solubilities on dental caries, the composition of the saliva, and the femurs of rats.


Tarnish of certain dental alloys.

Tarnish of certain dental alloys.


Chemical and physical studies of enamel from human teeth. I. Specific gravity and nitrogen content of enamel from different surfaces.


Experimental caries with human foods.

Experimental caries with human foods.


Salivary gland function in the rat. I. Flow, viscosity, and pH in the normal and duct-ligated rat.


A technique for the study of the internal structure of calcified tissues.


Reliability of measurements from cephalograms at the Burlington Orthodontic Research Centre.


The effect of pyridoxine and injected carbohydrate on incidence of caries, dentinal circulation related to diet.


The effects of neurohypophysial extracts on the water transfer across the wall of the isolated urinary bladder of the toad Bufo marinus.


Dental caries activity, and the pH, titratable alkalinity, and rate of flow of human parotid saliva.


Cytological appearances in the normal and activated parathyroid of the rat: a combined study by electron and light microscopy with certain quantitative assessments.


The experimental induction of superfoetation in the mouse.


The characterization of tetrahydrocorticosterone and of some alpha beta-unsaturated ketonic compounds simulating adrenal steroid metabolites in urine.


Goitrogens in milk.

Goitrogens in milk.


Variation in the number of corpora lutea and in the number and size of 6-day blastocysts in rabbits subjected to superovulation treatment.


The effect of hydrocortisone plus polyantibiotics upon the damaged and infected dental pulp of rat molars.


The action of different preparations of human chorionic gonadotrophin on the mouse ovary.


Role of the hypothalamus in pituitary-thyroid interplay.


The influence of age on litter-size.

The influence of age on litter-size.


Dimethylstilboestrol as an oestrogen inhibitor.


New material for somato-prosthesis.

New material for somato-prosthesis.


Mammary gland growth in male mice of the CHI strain after hypophysectomy and castration.


Procedures for computing the mean age of eruption of human teeth.


Modification of the oestrous cycle of the mouse by external stimuli associated with the male; changes in the oestrous cycle determined by vaginal smears.


Studies on human mouth protozoa.

Studies on human mouth protozoa.


Observations on the use of 2-methyl-9 alpha-fluorohydrocortisone in the maintenance of adrenalectomized patients.


A comparison of the salivary protease activity in the Harvard and Hunt-Hoppert caries-resistant and caries-susceptible rats.


The production of exophthalmos by androgens in two species of teleost fish.


Parabiosis in strains of caries-susceptible and caries-resistant rats.


The induction of deciduomata in the pseudo-pregnant rat by systemic administration of histamine and histamine releasers.


Production of clinical roentgenograms by means of compact radioactive x-ray and gamma-ray sources; an experimental study.


The hormonal genesis of mammary cancer. Proc. Soc. Endocr. 68th.


The use of the mammary-slice bioassay method for the estimation of insulin in glucagon. Proc. Soc. Endocr. 69th.


The experimental production of carcinoma of the tongue in mice.


Effect of sodium chloride intake and mineralocorticoid level on the granularity of juxtaglomerular cells.


Circulating insulin antagonists in diabetes mellitus. Proc. Soc. Endocr. 69th.


Histamine-oestrogen-progesterone complex associated with the decidual cell reaction and with ovum implantation. Proc. Soc. Endocr. 69th.


Poliomyelitis as a complex infection.

Poliomyelitis as a complex infection. Young cynomolgus monkeys inoculated intracerebrally with an attenuated Type 1 polio virus and, after 5 days, with a monkey adapted Coxsackie A-14 virus frequently became paralyzed. Neither virus alone was capable of inducing paralysis. Similar results were observed when the AB IV strain of Coxsackie A-7 was substituted for the A-14 virus. In this case the 2nd inoculation was made intramuscularly. Paralytic poliomyelitis may at times represent the summation of two infections, the total of motor neuron destruction by two independent and noninterfering enteroviruses.


Latent viral infection of cells in tissue culture. VI. Role of amino acids, glutamine, and glucose in psittacosis virus propagation in L cells. Mouse fibroblasts (L cells) fail to support the growth of psittacosis virus (6BC strain) if they are maintained on a medium containing only inorganic salts and glucose for 2 days prior to infection. Virus propagation can be stimulated by the addition of a synthetic medium containing amino acids, water-soluble vitamins, glutamine, glucose, and inorganic salts. By omitting single amino acids from the complete synthetic medium, tyrosine, threonine, methionine, isoleucine, phenylalanine, tryptophan, leucine, valine, and cysteine or cystine were found to be essential for stimulation, while lysine, arginine, histidine, hydroxyproline, proline, glutamic acid, aspartic acid, serine, alanine, and glycine were not essential. The cells on deficient media showed varying degrees of degenerative changes, but there was little correlation between ability to support psittacosis virus growth and morphologic condition of the cells. Glucose is also an essential component of the medium for viral growth, but the absence of glutamine had no effect on stimulation of virus propagation. L cell cultures maintained on media deficient in phenylalanine or tryptophan for 2 days before infection were also found to be incapable of supporting virus growth. The implications of this study in latent viral infections are discussed.


The cutaneous reaction to soluble antigen-antibody complexes; a comparison with the Arthus phenomenon. The in vivo activity of soluble antigen-antibody complexes was tested by a single intradermal injection in rabbits. Skin reactions were obtained marked by erythema, induration, and occasionally hemorrhage and necrosis. Microscopically, diffuse inflammation and occasional vascular necrosis could be found at all dosages. This indicates that soluble antigen-antibody complexes are phlogogenic and provides support for the suggestion that complexes are responsible for the lesions seen in serum sickness. The reactions were similar in severity to local passive Arthus (LPA) reactions at equal dosages of antibody in the dosage range studied. BSA antigen could be found in large concentrations in affected vessel walls of both reverse passive Arthus (RPA) and active or classical Arthus reactions. It is suggested that this predominantly vascular localization of antigen might bring about the relative severity of the RPA and active Arthus reactions, as contrasted to the complex and LPA reactions. The finding of affected vessels in the complex and LPA reactions containing little or no antigen and antibody, while these components were present in adjacent areas, suggests that the antigen-antibody combination may cause vascular reaction and damage by the release of physiologically active mediators from the tissue or tissue fluid.


Catalase requirement for mammalian cells in culture.


Enzymatic variants of influenza virus. II. Effect of environmental factors on enzymatic characteristics of a variant of influenza B virus. The rate of elution of the variant virus from chicken RBC is progressively decreased as the temperature of incubation is increased above 25 degrees C. The activity of the parent virus, on the other hand, is increased as the temperature is increased up to 40 degrees C. The major cause of the decreased activity of the variant at temperatures above 2S degrees C. is an inhibition of the variant enzyme rather than its inactivation. The activity of the variant enzyme is stimulated in the presence of strontium, calcium, and barium ions. Manganese has only a slight effect, and magnesium has no stimulatory effect on the elution of the variant virus. Elution of the variant at 37 degrees C. is progressively inhibited at pH values above 7, while the parent virus is still active at pH 8. In the absence of calcium the variant enzyme, hemagglutinin, and infectivity are more heat labile than those of the parent virus. The addition of calcium increases the heat stability of all three properties of the variant, and in the presence of calcium the infectivity of the variant is as stable as that of the parent virus.


Studies of the plasmin system. III. Physical properties of the two plasmin inhibitors in plasma. There are two inhibitors of plasmin in the plasma proteins of the human. alpha1-antiplasmin is heat-labile and migrates as an alpha1-globulin on electrophoresis. It combines non-dissociably with plasmin at a rate that depends on temperature. alpha2-antiplasmin is relatively more heat-stable and migrates as an alpha2-globulin on electrophoresis. It combines dissociably with plasmin independently of temperature.


Characterization of a factor formed in the course of adenovirus infection of tissue cultures causing detachment of cells from glass. Infectious tissue culture fluids of the majority of serotypes of adenovirus at low dilutions detach HeLa or KB cells from glass surfaces within a few hours after inoculation. A reproducible method for testing cell detachment was devised. The factor present in infectious tissue culture fluids and responsible for cell detachment is trypsin-sensitive and non-dialyzable; it is smaller and more resistant to the effect of heat or ultraviolet light than the infectious virus particle. Cell detachment activity was found to be temperature-dependent, and the cell-detaching titer of infectious tissue culture fluids was not affected by repeated exposure to HeLa cells. Inhibition of cell detachment by human or rabbit sera was observed only when other antibodies to adenovirus antigens were also present, but the antibody inhibiting cell detachment could not be correlated quantitatively with complement-fixing or homologous neutralizing antibody.


Inactivation of endotoxin by a humoral component. II. Interaction of endotoxin with serum and plasma. A humoral substance which inactivates endotoxin in vitro has been shown to be clearly distinguishable from complement, properdin, and specific antibody. For the present, it is designated "endotoxin-detoxifying component" or EDC. Animal species could be grouped in three categories with regard to the EDC activity of their sera; rat serum was highly potent; chimpanzee, dog, horse, and guinea pig sera were much less active; mouse, rabbit, and sheep sera exhibited no activity. The EDC potency of human sera varied widely, ranging from high to barely discernible activity. In contrast to the variations of EDC potency in serum, citrated plasma from all species manifested high potency of about the same magnitude. The influence of time, temperature, pH, and concentration of reactants on the inactivation of endotoxin by EDC was examined. EDC activity in plasma and serum was found to be labile to beating at 56 degrees C. for 1 hour. Bacterial endotoxins, derived by different isolation procedures from smooth and rough Gram-negative species, varied considerably in susceptibility to EDC action.


Effects of arsenic-azoproteins on mouse lymphoma cells in vivo; with observations on the effects of other anti-lymphoma agents, and on the susceptibility to these effects of lymphoma cells of various types. Conjugates made by coupling diazotized arsanilic acid with one or another of a variety of proteins regularly brought about the complete regression of established 6C3HED lymphomas in living mice without perceptibly harming the latter, while untreated control animals regularly died with lymphomatosis. Histologic studies made plain that the lymphoma cells promptly die in mice treated with the arsenic-azoproteins, while those in untreated control animals continue to proliferate. Various inorganic and organic arsenicals (including arsanilic acid and 4-arsonophenyldiazotate) were essentially devoid of effect on the lymphoma cells in vivo, and this proved true as well of the proteins employed (serum albumins and globulins procured from several species, casein, and ovalbumin). Mixtures of arsanilic acid and the several proteins, various sulfur-azoproteins, and a number of other substances-viz., amethopterin, chlorambucil, 6-mercaptopurine, 8-azaguanine, azaserine, 6-azauracil, 5-fluorouracil, thioTEPA, and DON, each given in maximal tolerated amounts-also failed to influence notably the course of established 6C3HED lymphomas in vivo. Although readily overcoming Lymphoma E9514 cells growing in the subcutaneous tissues of susceptible mice, the arsenic-azoproteins had little or no effect once these cells had reached the livers and spleens of susceptible hosts. Furthermore the arsenic-azoproteins had little or no effect in vivo on the cells of Lymphoma AKRL1, L1210, and L4946. The findings were considered in relationship to the respective susceptibilities of several types of lymphoma cells to other anti-lymphoma agents-notably guinea pig serum, immune serums prepared in rabbits with mouse lymphoma cells as antigens, and a variety of chemical compounds. Taken together, the observations provide proof that lymphoma cells of various types, although resembling one another quite closely in growth characteristics following transplantation in susceptible hosts, and in morphology as disclosed by ordinary microscopy, differ notably in susceptibility to the effects of the several anti-lymphoma agents.


Inactivation of endotoxin by a humoral component. III. Role of divalent cation and a dialyzable component. The uniformly high potency of citrated plasma as compared with the limited capacity of serum to inactivate endotoxin in vitro was found to be a consequence of the anticoagulant employed in collecting the plasma. Addition of calcium to plasma suppressed the activity of its endotoxm detoxifying component (EDC) whereas the addition of calcium-binding anticoagulants rendered serum comparable to plasma. Dialysis of plasma resulted in a marked reduction of its EDC activity despite the concommittant elimination of calcium. EDC activity could then be fully restored upon the addition of calcium-binding anticoagulants. Resin-treated plasma, without added anticoagulant, had EDC activity equal to plasma obtained with calcium-binding anticoagulants. Following dialysis, resin-treated plasma also sustained a marked reduction in EDC activity which could be fully restored by calcium-binding anticoagulants. Restoration was also obtained with the dialysate even after ashing. These findings indicated that the suppression of EDC activity by calcium is not direct but is mediated through its effects on an anionic component of plasma which is required for inactivation of endotoxin by EDC.


Effects of discrimination performance of similarity of previously acquired stimulus names.


Colicine K. III. The immunological properties of a substance having colicine K activity. By immunological means it has been shown that colicine K is associated with the O antigen of the colicinogenic bacillus E. coli K(235) L(+)OC(+). The colicine K-O antigen complex elicits the formation of at least two types of antibodies, one a precipitin, the other a colicine-neutralizing antibody. The first precipitates colicine K without neutralizing it, the second neutralizes the colicine without precipitating it. Unlike the purified colicine K complex, the colicine protein component of the O antigen is precipitable by the neutralizing antibody. There is no demonstrable serological relationship between colicine K and phage T(6). These two agents must be considered to be separate and distinct entities.


A study of fittingness of signs to words by means of the semantic differential.


Folinic acid and non-dialyzable materials in the nutrition of malaria parasites. The extracellular survival of the malaria parasite Plasmodium lophurae was favored on the 4th day of incubation in vitro by the presence in the medium of added folinic acid at a concentration of about 5 microg. per ml. The development of the human malaria parasite P. falciparum intracellularly in suspensions of human erythrocytes was better in a medium with a high than in one with a low concentration of folic acid. In the early extracellular development of P. lophurae in vitro erythrocyte extract could be partially replaced by certain yeast protein preparations and by a non-dialyzable fraction, free from hemoglobin, prepared from duck erythrocyte extract by means of starch electrophoresis.


Inhibition with reinforcement (conditioned inhibition).


Extinction and spontaneous recovery of conditioned eyelid responses as a function of amount of acquisition and extinction training.


Facilitation of mirror-image word identification by mirror-image perceptual set.


Reliability of judgments of figural complexity.


A scale of apparent intensity of electric shock.


Pursuit rotor performance as a function of delay of information feedback.


Generalization of an instrumental response with variation in two attributes of the CS.


Learning and performance in a tracking task under two levels of achievement information feedback.


The magnitude of binocular summation as a function of the method of stimulus presentation.


Amount of information gained during brief exposures of numerals and colors.


The effect of a stimulant and a depressant drug on a measure of reactive inhibition.


Discrepancy from adaptation level as a source of affect.


The labelling of mammalina spermatozoa with radioactive tracers.


Absolute judgments of static perspective transformations.


Anagram solution times: a function of letter order and word frequency.


Orientation in paleotropical bats. II. Megachiroptera.


The inheritance and expression of disorganization, an unusual mutation in the mouse.


X-irradiation of the gaint amoeba, Pelomyxa illinoisensis. II. Further studies on recovery following supralethal exposure.


Anti-lens sera as a mutagen in rabbits.

Anti-lens sera as a mutagen in rabbits.


Distribution of ribonucleoprotein during neural induction in the frog embryo.


Nuclear and cytoplasmic changes in fat body cells of the queen bee during metamorphosis.


Hearing loss in persons of advanced age; influence of factors other than the normal aging process.


The prevention and management of football injuries.


The pediatrician and behavior problems of children.


An analysis of the causes of blindness in Florida.


Perforation of the interventricular septum due to myocardial infarction diagnosed antemortem.


Epidemic neuromyasthenia, an outbreak in Punta Gorda, Florida; an illness resembling Iceland disease.


Management of tension and anxiety states with hydroxyzine hydrochloride.


A re-evaluation of breast cancer and its management.


We've heard that song before.

We've heard that song before.


Chloride levels in parotid secretion.

Chloride levels in parotid secretion.


The influence of growth rate and aeration on the respiratory and cytochrome system of fluorescent pseudomonad grown in continuous culture.


The induced synthesis of hydrogenase by Hydrogenomonas facilis.


Electron microscope studies of HeLa cells infected with herpes virus.


Quantitative studies on the growth of herpes virus in HeLa cells.


Ammonium alginate wool as a filter for collecting micro-organisms from large volumes of air.


A comparative study of cytoplasmic inclusions (volutin granules) in different species of trypanosomes.


Bacteriocin-like material produced by Pasteurella pestis.


Nutritional studies of Zygorhynchus species.


The bacterial component of soybean root nodules; changes in respiratory activity, cell dry weight and nucleic acid content with increasing nodule age.


The keeping quality of freeze-dried Brucella abortus strain 19 vaccine.


An aromatic intermediate in the bacterial oxidation of quinic acid.


Homotypic non-exclusion by vesicular stomatitis virus in chick cell culture.


Some aspects of soil fungistasis.

Some aspects of soil fungistasis.


Shortened latency' as a result of multiple infection by vesicular stomatitis virus in chick cell culture.


The effect of sudden chilling on Escherichia coli.


Formation of enzymes involved in pyrimidine synthesis and amino acid metabolism in Escherichia coli.


A defined medium for the growth of the thermophilic actinomycete Micromonospora vulgaris.


Hereditary aberrancy in growth of some Bacillus megaterium strains.


Induction of bacteriolysis by cysteamine and its derivatives.


Delayed light action spectra of several algae in visible and ultraviolet light. Action spectra for delayed light production by several algae were determined from 250 to 750 mmicro incident light. In the visible portion of the spectrum the action spectra resemble those reported by previous workers for photosynthesis and light emission. Blue-green algae had a maximum at 620 mmicro, red algae at 550 mmicro, whereas green and brown algae have action spectra corresponding to chlorophyll and carotenoid absorption. In the ultraviolet portion of the spectrum delayed light is emitted by algae down to 250 mmicro incident light. The action spectra of the different algae are not alike in the ultraviolet portion of the spectrum. This indicates that pigments other than chlorophyll must be sensitizing or shielding the algae in the ultraviolet region.


The cation content of phospholipides from swine erythrocytes. Phospholipides from swine erythrocytes were isolated and separated into four reproducible fractions. One of the fractions seems to be pure phosphatidylserine. The others are almost certainly not single compounds, although the analytical data indicate that they represent mixtures considerably simpler than the parent mixture extracted from the cells. All four fractions contained Na(+) and K(+), but very little Ca(2+). Sodium was the predominant cation in two of the fractions under all conditions although the major intracellular cation was potassium. In the other two fractions the ratio Na/K varied with the extraction procedure largely because the quantity of K(+) seemed to depend on the solvent system used. There appear to be reasons to believe that the entire system of phospholipides binds Na(+) preferentially. In addition, it was observed that the quantity of Na(+) found in the lipide extracts varied when the extrusion of Na(+) from the cells was made to vary. Both of these observations are consistent with the possibility that the phospholipides play some part in the extrusion of Na(+) from these cells.


Comparative studies of three methods for measuring pepsin activity. Comparison has been made of a simple method originated by Absolon and modified in our laboratories for assay of proteolytic activity using RISA (radioactive iodinated serum albumin-Abbott Laboratories), with the commonly used photometric methods of Anson and Kunitz. In this method, pepsin was incubated with an albumin substrate containing RISA, followed by precipitation of the undigested substrate with trichloroacetic acid and measurement of radioactive digestion products in the supernatant fluid. The I(131)-albumin bond was shown in the present studies to be altered only by the proteolytic activity, and not by the incubation procedures at various values of pH. Any free iodine present originally in the RISA was removed by a single passage through a resin column (amberlite IRA-400-C1). Pepsin was shown to be most stable in solution at a pH of 5.5. Activity of pepsin was shown to be maximal when it was incubated with albumin at a pH of 2.5. Pepsin activity was shown to be altered in the presence of various electrolytes. Pepsin activity measured by the RISA and Anson methods as a function of concentration or of time of incubation indicated that these two methods are in good agreement and are equally sensitive. Consistently smaller standard errors were obtained by the RISA method of pepsin assay than were obtained with either of the other methods.


The thermal stability of rhodopsin and opsin. Rhodopsin, the red photosensitive pigment of rod vision, is composed of a specific cis isomer of retinene, neo-b (11-cis), joined as chromophore to a colorless protein, opsin. We have investigated the thermal denaturation of cattle rhodopsin and opsin in aqueous digitonin solution, and in isolated rod outer limbs. Both rhodopsin and opsin are more stable in rods than in solution. In solution as well as in rods, moreover, rhodopsin is considerably more stable than opsin. The chromophore therefore protects opsin against denaturation. This is true whether rhodopsin is extracted from dark-adapted retinas, or synthesized in vitro from neo-b retinene and opsin. Excess neo-b retinene does not protect rhodopsin against denaturation. The protection involves the specific relationship between the chromophore and opsin. Similar, though somewhat less, protection is afforded opsin by the stereoisomeric iso-a (9-cis) chromophore in isorhodopsin. The Arrhenius activation energies (E(a)) and entropies of activation (DeltaSdouble dagger) are much greater for thermal denaturation of rhodopsin and isorhodopsin than of opsin. Furthermore, these values differ considerably for rhodopsins from different species -frog, squid, cattle-presumably due to species differences in the opsins. Heat or light bleaches rhodopsin by different mechanisms, yielding different products. Light stereoisomerizes the retinene chromophore; heat denatures the opsin. Photochemical bleaching therefore yields all-trans retinene and native opsin; thermal bleaching, neo-b retinene and denatured opsin.


Potassium-dependent sodium extrusion by cells of Porphyra perforata, a red marine alga. Potassium-free artificial sea water causes a loss of cell potassium and a gain of cell sodium in Porphyra perforata, which is not attributable to an inhibition of respiration. On adding KCl or RbCl to such low potassium, high sodium tissues, net accumulation of potassium or rubidium takes place, accompanied by net extrusion of sodium. Rates of potassium or rubidium accumulation and sodium extrusion are proportional to the amount of KCl or RbCl added only at low concentrations. Saturation of rates is evident at KCl or RbCl concentrations above 20-30 mM, suggesting the role of an ion carrier mechanism of transport. Evidence for and against mutually dependent sodium extrusion and potassium or rubidium accumulation is discussed.


Some observations on cardiac automatism in certain animals. Certain aspects of the acetylcholine hypothesis of cardiac automaticity have been tested in vitro with spontaneously beating cardiac tissue from rabbits, rats, dams, and hagfish. The beat of atria from rabbits and rats may be depressed or excited by acetylcholine, depending upon the state of the tissue. Proguanil and cocaine inhibition of the beat in the rat may be antagonized by acetylcholine so that reversal of the depression occurs. The action of acetylcholine on the hearts of clams was found to be strictly inhibitory. Proguanil and cocaine, in contrast to their action on mammalian atria, exert a stimulatory effect on the heart of the molluscs studied. In fact, cocaine stimulated these hearts when they were inhibited by acetylcholine. Studies on the non-innervated hagfish heart revealed that this tissue is completely insensitive to the action of acetylcholine. Extracts prepared from beating hearts of this species will accelerate hypodynamic hearts of the hagfish as well as of the mussel. An extract of the neurogenic lobster heart was without effect on the hagfish heart. Proguanil was likewise ineffective in concentrations which produced inhibition and excitation in rat and clam hearts respectively. It was concluded that acetylcholine does not play a role in the myogenic automatism of all species, and that another mechanism is responsible is suggested on the basis of results obtained in the hagfish hearts.


The effect of ascorbic acid oxidation on the incorporation of sulfate by slices of calf costal cartilage. A marked inhibition of the incorporation of S(35)-sulfate by normal calf costal cartilage was produced by potassium ascorbate in the presence of catalytic amounts of cupric ions. The effect of the various components of the ascorbic acid oxidizing system (potassium ascorbate, cupric ions, cuprous ions, hydrogen peroxide, dehydroascorbic acid) was investigated. The results of experiments in which hydrogen peroxide, catalase, or sodium azide were used singly or in combination suggest that the inhibition produced by the ascorbic acid oxidizing system is due, to a considerable extent, to the production of hydrogen peroxide. Dehydroascorbic acid was also found to inhibit the incorporation of S(35)-sulfate by cartilage slices. However, the gradual fall in pH which resulted from the addition of dehydroascorbic acid could account to a large extent for the inhibitory effect observed because the incorporation of S(35)-sulfate by cartilage slices decreases sharply as the pH is lowered. The incorporation of S(35)-sulfate by cartilage slices is inhibited also by increasing the concentration of phosphate.


Tubular secretion of creatine, trimethylamine oxide, and other organic bases by the aglomerular kidney of Lophius americanus. Creatine and trimethylamine oxide (TMAO) are the chief nitrogenous constituents of normal Lophius urine, and both of these organic bases characteristically have high urine/plasma concentration ratios. Competition studies involving various organic bases indicate that creatine and TMAO are excreted independently by separate transport mechanisms. TMAO excretion is inhibited competitively by tetraethylammonium ion (TEA) and by cyanine dye No. 863-compounds previously shown to be transferred actively by an organic base-secreting mechanism of general occurrence among vertebrates. TEA does not inhibit competitively the active tubular reabsorption of TMAO in Squalus with doses which markedly depress its tubular excretion in Lophius. Glycine, which inhibits creatine reabsorption in the dog, does not interfere competitively with its secretion in Lophius.


Studies on the origin of bacterial viruses. V. The effect of temperature on the terramycin-resistant and phage-producing cells of Bacillus megatherium cultures. The growth rates, the mutation frequency rate constants of the terramycin-resistant cells, the burst size of the phage-producing cells, and the ratio of phage to cells all have a temperature coefficient of about 2 from 20 to 35 degrees (micro = 9 x 10(3) calories), with a maximum at 40 degrees . The mutation frequency rate constant (or time rate constant) of the phage-producing cells increases from 20 to 45 degrees with a temperature coefficient of about 3 (micro = 2 to 3 x 10(4) cal.). The change in the values for the growth rate, mutation rate, and cell volume occurs in less than 1 hour, after the temperature is changed. The value for the burst size of phage-producing cells changes for 3 to 4 hours. Prolonged growth of megatherium 899 at 48 to 50 degrees results in the production of C + S phage, in place of T. Returning the culture to 25 degrees results in the production of small T phage.


Ion transport in Nitellopsis obtusa.

Ion transport in Nitellopsis obtusa. The distribution and rates of exchange of the ions sodium, potassium, and chloride in single internodal cells of the ecorticate characean, Nitellopsis obtusa, have been studied. In tracer experiments three kinetic compartments were found, the outermost "free space" of the cell, a compartment we have called "protoplasmic non-free space", and the cell sap. The concentrations in the vacuole were 54 mM Na(+), 113 mM K(+), and 206 mM Cl(-). The steady state fluxes across the vacuolar membrane were 0.4 pmole Na(+)/cm.(2) sec., 0.25 pmole K(+)/cm.(2) sec., and 0.5 pmole Cl(-)/cm.(2) sec. The protoplasmic Na/K ratio is equal to that in the vacuole but protoplasmic chloride is relatively much lower. Osmotic considerations suggest a layer 4 to 6 micro thick with sodium and potassium concentrations close to those in the vacuole. The fluxes between protoplasm and external solution were of the order of 8 pmoles Na(+)/cm.(2) sec. and 4 pmoles K(+)/cm.(2) sec. We suggest that the protoplasm is separated from the cell wall by an outer protoplasmic membrane at which an outward sodium transport maintains the high K/Na ratio of the cell interior, and from the vacuole by the tonoplast at which an inward chloride transport maintains the high vacuolar chloride. The tonoplast appears to be the site of the principal diffusion resistance of the cell, but the outer protoplasmic membrane probably of the main part of the potential.


The entrance of water into beef and dog red cells. The rate constants for diffusion of THO across the red cell membrane of beef and dog, and the rate of entrance of water into the erythrocytes of these species under an osmotic pressure gradient have been measured. For water entrance into the erythrocyte by diffusion the rate constants are 0.10 +/- 0.02 msec.(-1) (beef) and 0.14 +/- 0.03 msec.(-1) (dog); the permeability coefficients for water entrance under a pressure gradient of 1 osmol./cm(3) are 0.28 See PDF for Equation These values permit the calculation of an equivalent pore radius for the erythrocyte membrane of 4.1 A for beef and 7.4 A for dog. In the beef red cell the change in THO diffusion due to osmotically produced cell volume shifts has been studied. The resistance to THO diffusion increases as the cell volume increases. At the maximum volume, (1.06 times normal), THO diffusion is decreased to 0.84 times the normal rate. This change in diffusion is attributed to swelling of the cellular membrane.


The action of enzymes on rhodopsin.

The action of enzymes on rhodopsin. The effects have been examined of chymotrypsin, pepsin, trypsin, and pancreatic lipase on cattle rhodopsin in digitonin solution. The digestion of rhodopsin by chymotrypsin was measured by the hydrolysis of peptide bonds (formol titration), changes in pH, and bleaching. The digestion proceeds in two stages: an initial rapid hydrolysis which exposes about 30 amino groups per molecule, without bleaching; superimposed on a slower hydrolysis which exposes about 50 additional amino groups, with proportionate bleaching. The chymotryptic action begins at pH about 6.0 and increases logarithmically in rate to pH 9.2. Trypsin and pepsin also bleach rhodopsin in solution. A preparation of pancreatic lipase bleached it slightly, but no more than could be explained by contamination with proteases. In digitonin solution each rhodopsin molecule is associated in a micelle with about 200 molecules of digitonin; yet the latter do not appear to hinder enzyme action. It is suggested that the digitonin sheath is sufficiently fluid to be penetrated on collision with an enzyme molecule; and that once together the enzyme and substrate are held together by intermolecular attractive forces, and by the "cage effect" of bombardment by surrounding solvent molecules. The two stages of chymotryptic digestion of rhodopsin may correspond to an initial rapid fragmentation, such as has been observed with many proteinases and substrates; superimposed upon a slower digestion of the fragments. Since the first phase involves no bleaching, this may mean that rhodopsin can be broken into considerably smaller fragments without loss of optical properties.


Realistic model of a fixed-charge membrane according to the theory of Teorell, Meyer, and Sievers. A realistic model of a fixed-charge membrane was constructed to elucidate the principles involved in the Teorell-Meyer-Sievers theory. Polyelectrolyte solutions (polystyrene sulfonic acid or gelatin) were used in a multicompartment cell to serve as the "membrane." The ionic concentration and potential differences between the compartments served as a finite increment approximation to a continuous membrane phase. The profiles obtained for a positively and negatively charged membrane gave striking support for the theory.


Electrical activity in the chemoreceptors of the blowfly. I. Responses to chemical and mechanical stimulation. The electrical responses of the neurons associated with the various types of chemosensory hairs of the blowfly, Phormia regina Meigen, following stimulation by chemical and mechanical means have been studied. The singly innervated chemosensory hairs on the ovipositor, maxillary palpi, and antennae respond vigorously to chemical stimulation, but not to mechanical stimulation. The triply innervated chemosensory hairs on the labellum, tarsus, and wing have two neurons which respond only to chemical stimuli. The third neuron responds only to mechanical stimulation. The differential responses of the two chemosensory neurons to various chemical stimuli following the removal of the tip of the hair suggest that the structures responsible for chemoreception are located throughout the distal processes of these neurons. The response of the third neuron to mechanical stimulation is similar to the response recorded from the neuron associated with one type of tactile hair which responds to motion and not to steady deformation. Recordings have been made from the neurons associated with purely tactile hairs using the cut hair as an extension of the micropipette. The mechanosensory neuron of the wing chemosensory hair is capable of responding at the rate of at least 600 impulses per sec. and may serve to indicate changes in air flow over the wing surfaces during flight to enable the fly to correct the wing camber and attack angle.


Experimental study of osmosis through a collodion membrane. Experiments were carried out on a collodion membrane in order to study the factors that determine direction and magnitude of net flow of water across a membrane permeable to the solvent and to some of the solutes present. The solutes used were all non-ionic. When only one solute was present and there was no difference of hydrostatic pressure across the membrane, water flowed toward the side where its vapor pressure was lower, but the rate of transfer depended upon the nature of the solute: for a given difference in osmolality across the membrane, the rate increased with the molecular volume of the solute and reached its maximum with the solute to which the membrane was impermeable. These results led to the experimental demonstration that in the presence of two or more solutes of different molecular volumes, of which one at least can diffuse through the barrier, the net transfer of water can take place against its vapor pressure gradient. Some of the physicochemical and physiological implications of the data are discussed.


Electrical activity in the chemoreceptors of the blowfly. II. Responses to electrical stimulation. An analysis of the various parts of the electrical responses to the chemical and electrical stimulation of a single labellar chemosensory hair of the blowfly, Phormia regina, indicates that the recording conditions for the spike potentials approximate the intracellular recordings made in other types of sense cells. The large positive resting potential probably arises from the basement membrane of the hypodermal cells and neurilemma rather than from the neurons at the base of the chemosensory hair. The responses to polarizing currents passed through single chemosensory hairs support this analysis. The behavioral responses to similar polarizing currents are shown to result from the action of the current on the neurons at the bases of the adjacent chemosensory hairs. The reported neural interaction of the two chemosensory neurons associated with the chemosensory hair is probably due to the physical-chemical attributes of the stimulating solution rather than to any real neural interaction. Observations on the latency of the initial nerve impulse in response to chemical stimulation indicate that the chemosensory neurons are normally free from spontaneous spike activity.


The photosensitive retinal pigments of fishes from relatively turbid coastal waters. Digitonin extracts have been prepared from the retinae of a dozen species of marine and euryhaline teleost fishes from turbid water habitats. Spectrophotometric analysis of the extracts shows that the photosensitive retinal pigments of these species have maximum absorption above 500 mmicro. In nine species there are retinene(1) pigments with lambda(max) between 504 and 512 mmicro. In the marine but euryhaline mullet, Mugil cephalus, there is a porphyropsin with lambda(max) 520 mmicro. A mixture of rhodopsin and porphyropsin in an extract of a marine puffer, Sphoeroides annulatus, was disclosed by partial bleaching with colored light. In addition, one other species has a 508 mmicro pigment, of which the nature of the chromophore was not determined. The habitats in which these fishes live are relatively turbid, with the water greenish or yellowish in color. The spectral transmission of such waters is probably maximal between 520 and 570 mmicro. It is suggested that the fishes have become adapted to these conditions by small but significant shifts in spectral absorption of their retinal pigments. These pigments are decidedly more effective than rhodopsin in absorption of wavelengths above 500 mmicro. This offers a possible interpretation of the confusing array of retinal pigments described from marine and euryhaline fishes.


A comparison of figural after-effects from the perception of real and of apparent movement.


Effect of reserpine on avoidance of humans by Rhesus monkeys.


Music therapy for the mentally ill. I. A historical sketch and a brief review of the literature on the physiological effects and on analysis of the elements of music.


Delay and risk: influence of a delay in performance on maximum risk-taking levels.


The significance of assumptive and philosophic operations in psychological methodology.


Secondary reinforcement and avoidance conditioning.


The effects of emotionality on concept formation.


The Minnesota Teacher Attitude Inventory in an American minority-group school setting. II. Indirect validation as a test of pupil-directedness.


A historical note on retention.

A historical note on retention.


Progression from simple to complex as a molar law of learning.


Hypnotherapy with borderline schizophrenics.


Serial position effects and the Marbe effect in the free recall of meaningful words.


Randomized stimuli and the non-independence of successive responses at the visual threshold.


An experimental investigation of non-randomness in parapsychological targets and calls.


Name styles in relation to personality.

Name styles in relation to personality.


Apparatus for presentation of stimuli and measurement of response times in reaction time experiments.


A transistor psychogalvanometer.

A transistor psychogalvanometer.


Affective responses to the concept of death in a population of children and early adolescents.


Conditioned responses in the opossum.

Conditioned responses in the opossum.


Kinesthetic cues in the development of time concepts.


Conceptual block-sorting as a function of type and degree of mastery of discriminative verbal responses.


Raven's progressive matrices: a review and critical evaluation.


The development of paw preferences in cats and monkeys.


Reevaluation of the revised Stanford-Binet scale, form L vocabulary as a test of intelligence for the kindergarten and primary school child.


The ecological veracity of the self-report.


Cultural pressure and WAIS scatter in traditional Jewish setting.


Preirradiation as a factor in the prevention of irradiation deaths in rats.


A study of seventh grade children's reading of comic books as related to certain other variables.


Substitution with interrupted tasks of differing valence.


Maternal age at time of first litters in mice.


Relationship of age to swelling properties of human diaphragm tendon in acid and alkaline solutions.


The effect of age and temperature on the cerebral energy requirement in the rat.


The blood picture of the aging male rat.


Physiologic aspects of aging. II. Radiocyanocobalamin absorption and protein digestion by the rat.


Studies of growth throughout the life span in Japanese. II. Beard growth in relation to age, sex, heredity, and other factors.


Effect of non-ovarian hormones on the endometrium of castrate guinea pigs.


Effect of aging on plantar flexor and superficial abdominal reflexes in man; a clinical and electromyographic study.


Age differences in retention of learning.


Intrastate migration of the pre-aged and the aged in Texas, 1935-1940.


A word-association test of emotional disturbance in older women.


Aging processes in speech: pitch and duration characteristics.


On an infection of a human eye with Philophthalmus sp. in Ceylon.


Protein metabolism in trematode parasites.


On some trematodes from the manicou, Didelphis marsupialis insularis (Allen) from the West Indies.


Helminth parasites of Hertfordshire birds. II. Cestoda.


Symposium: problems of fixation in histochemistry.


Fixation in cytochemistry and electron-microscopy.


Effects of fixation on carbohydrate histochemistry.


The relationship between fixation and techniques for the histochemical localization of hydrolytic enzymes.


Effects of fixation in lipoid histochemistry.


Studies in histochemistry. II. Quantitative histochemical estimation of activities of alkaline and acid phosphomonoesterases.


Improved technique for the histochemical demonstration of succinic dehydrogenase in brain tissue.


Acetylation and nitrosation of tissue amines in histochemistry.


Staining properties of indicator dyes in nonaqueous solution, in relation to surface acid and basic strength of tissue proteins, and to metachromasia.


Physical and chemical protection of cell constituents and the precise localization of enzymes.


A note on cholinesterase activity in post-mortem tissues.


The fimbrial antigens of Shigella flexneri.


Another test for heterogeneity of host resistance in dilution assays.


The growth of micro-organisms in vivo with particular reference to the relation between dose and latent period.


The development of homologous neutralizing antibody during a type 1 poliomyelitis epidemic.


Brill-Zinsser disease; the possibility of its occurrence in Britain.


Airborne micro-organisms: a technique for studying their survival.


Leptospiral infection rates of wild rats in Britain.


A COMPARISON between MacConkey broth and glutamic acid media for the detection of coliform organisms in water.


Studies of the loss of viability of bacterial aerosols. III. Factors affecting death rates of certain non-pathogens.


Sporadic acute respiratory infections in adults with special reference to adenovirus infections.


An improved assay method for neutralizing antibodies against influenza viruses.


Increased susceptibility of mice with brucellosis to bacterial endotoxins.


The distribution of Forssman blood factors in individuals of various artiodactyl species.


Antigenic variation in relation to classification of Shigella flexneri.


Studies on serum bactericidal activity; interrelationships of heparin, citrate, protamine and xirradiation on serum and plasma bactericidal activity against Bacillus subtilis.


The magnitude of the immune response incited by killed and attenuated mycobacteria.


Preparation and immunologic properties of trifidin A, an antigen from giant ragweed pollen.


The behavior of different strains of poliomyelitis virus in the complement fixation reaction. I. Comparison of sensitivity of antigens derived from laboratory strains and patient's own infecting strain.


The agar diffusion precipitin technique: a comparison of the simple and double diffusion methods.


The specific hapten of group C (group II alpha) meningococcus. I. Preparation and immunological behavior.


The specific hapten of group C (group II alpha) meningococcus. II. Chemical nature.


Studies of rickettsial toxins. IV. Cardiovascular functional abnormalities induced by Rickettsia mooseri toxin in the white rat.


Passive cutaneous anaphylaxis in the mouse.


Virological aspects of Kyasanur Forest disease.


Clinical observations on Kyasanur Forest disease cases.


Observations on the properties of a piperidinomethylpyrazolone derivative.


Psychotherapy and the general practitioner.


New virus disease; Kyasanur Forest disease.


Familial leprosy.

Familial leprosy.


Colposcopy in a family planning clinic.

Colposcopy in a family planning clinic.


Erythema exudative multiforme.

Erythema exudative multiforme.


Congenital syphilitic retrobulbar neuritis.


Trichomonas vaginalis infestation of suburethral canal.


Osteo-articular lesions in smallpox.

Osteo-articular lesions in smallpox.


Survival of V. Cholerae and other intestinal pathogens in water.


Mastoid surgery technique further improved.


Preliminary observations on stapes mobilisation in otosclerosis.


Management of sexual debility in young men, the abuse of testicular hormone.


Gargoylism.

Gargoylism.


Unusual features in a case of typhoid fever.


A study of intrapleural pressure of the affected side in pleurisy with effusion.


Observations on contact dermatitis at Zaidpur.


Clinical trial with 11,925 in amoebiasis.


The Kerala food poisoning.

The Kerala food poisoning.


Pulmonary function tests: a further study.


Medico-social problems of old age.

Medico-social problems of old age.


A leech in the lung.

A leech in the lung.


Prednisone in small doses in the treatment of tuberculosis.


Protective effect of penicillin on mice infected with penicillin resistant and sensitive strains of Staphylococcus.


Effect of dietary fats on experimental tuberculosis of mice.


On plant anticoagulants.

On plant anticoagulants.


Suprapubic lithotomy with primary closure of bladder.


A new method of testing spermicidal action of foam tablets.


Strangulation of gut by abnormal mesenteric band of the Meckel's diverticulum.


Muscular dystrophy with cardiac involvement.


Electrocardiographic changes in myopathy.


Atypical Vogt-Koyanagi syndrome.

Atypical Vogt-Koyanagi syndrome.


Experimental cataract in protein deficiency.


Experiences with meprobamate (miltown) in the treatment of psychiatric syndromes.


The surgeon's training in India: a plea for reorientation.


Arrhenoblastoma of the ovary.

Arrhenoblastoma of the ovary.


Kartagener's syndrome.

Kartagener's syndrome.


Lymphatic cyst of the mesentery mimicking peptic ulcer.


Hydatid cyst of the spleen.

Hydatid cyst of the spleen.


Intraosseous cystic lesion caused by schwannoma.


The camp for diabetic children.

The camp for diabetic children.


Oral hypoglycemic agents.

Oral hypoglycemic agents.


Diabetes with pregnancy.

Diabetes with pregnancy.


Diabetes: errors in diagnosis.

Diabetes: errors in diagnosis.


Glucagon: the hyperglycemic-glycogenolytic factor.


The diabetic personality.

The diabetic personality.


The routine use of a spray-on plastic dressing in the care of surgical wounds.


Pneumonectomy for tuberculosis bronchostenosis.


Trends in mental health that concern general practice.


Postoperative care.

Postoperative care.


Obstructive jaundice and extrahepatic portal hypertension with emphasis on the hazard of surgical expioration.


Constitutional hyperbilirubinemia (Gilbert's disease): case report and review.


The position of civilian members of the medical professions in time of armed conflict.


Folic acid in purified preparations of members of the psittacosis group of micro-organisms.


Detection of poliovirus I in monkey kidney cultures inoculated with overwhelming dose of adenovirus 4.


Natural occurrence of tularemia in marsupials, carnivores, lagomorphs, and large rodents in southwestern Georgia and northwestern Florida.


The effect of cortisone on the lethality of psittacosis virus for the chick embryo.


Susceptibility to respiratory infections of animals exposed to ozone. I. Susceptibility to Klebsiella pneumoniae.


Leiomyosarcoma of the stomach.

Leiomyosarcoma of the stomach.


The metabolic response to surgical treatment.


Urologic complications of obstetrics and gynecology.


Transperitoneal nephrectomy for ectopic kidney.


Studies of technics for the isolation of leptospires. I. The suitability of 1 to 2 day old baby chicks as compared to hamsters for the isolation of various leptospiral serotypes.


Some new myologic and neurologic concepts of the human urinary bladder.


Separation of mixtures of two drugresistant strains of feline pneumonitis virus by limiting dilution passage in chick embryo yolk sac.


Hyaluronic acid: a required component of beta hemolytic streptococci for infecting mice by aerosol.


Laboratory studies on some biological properties of the Far East influenza virus.


The relationship between insusceptibility to phagocytosis and virulence of certain Klebsiella pneumoniae strains.


Ectopic pregnancy: pathologic features and management of unusual types.


The effect of chemotherapeutic agents upon the growth of Cryptococcus neoformans.


A study of the fate of Pasteurella pestis following intracardial injection into guinea pigs.


Pilonidal cyst and sinus: indications for operation.


Cobalt bomb therapy for recurrent carcinoma of the rectum.


Peculiarities of carcinoma of the lung.

Peculiarities of carcinoma of the lung.


The effect of sublethal whole-body x-radiation on active immunity.


Tympanoplasty.

Tympanoplasty.


RAFFAELE PAOLUCCI DI VALMAGGIORE; 1892-1958.


Henry W. Meyerding assumes presidency of International College of Surgeons.


PROF. A. MARIO DOGLIOTTI named president-elect of International College of Surgeons.


Group A streptococcus infections in wild rodents.


DR. EDWARD L. Compere installed as president of United States Section.


DR. GEORGE STREAN inducted into presidence of Canadian Section.


CLAIRE LEROY STRAITH: 1891-1958.

CLAIRE LEROY STRAITH: 1891-1958.


The surgical patient: oral bouillon feedings.


Fibrinolysis in surgical and nonsurgical patients.


Spontaneous rupture of a normal spleen: report of a case.


The plethysmographic peripheral vascular study.


Hydronephrosis: an historical study.

Hydronephrosis: an historical study.


Spontaneous exchange of blood between mother and fetus, preventing hemolytic disease in newborn.


Keratoplasty in the Philippines: a review.


Technic of dissection for carcinoma of the head and neck: extensions and modifications.


Fullthickness buried boiled skin graft; a preliminary report.


Atypical congenital megacolon.

Atypical congenital megacolon.


The physiologic aspects of thoracic trauma.


Papillary and follicular carcinoma of the thyroid: analysis of seventy-seven cases.


Bioatomic medicine and western civilization.


Paolucci the man.

Paolucci the man.


Ernest G. Abraham joins journal editorial board.


A contemporary controversy.

A contemporary controversy.


Eightieth birthday greetings to Prof. Ernst Sachs.


Morphology in medicine; a reawakening.

Morphology in medicine; a reawakening.


Some histochemical observations on the human eccrine sweat glands. IV. The recovery from the effects of profuse sweating.


Serum lipoproteins in psoriasis.

Serum lipoproteins in psoriasis.


The behavior of disulfide bonds of human serum treated with alkaline solutions.


The behavior of disulfide bonds of mouse organs after alkali treatment; determination with Bennett's reagent dissolved in toluene-aniline.


The effect of methylcholantrene and benzpyrene painting on the disulfide bonds of mouse epidermis.


Metabolic studies in psoriasis; skin potassium and plasma potassium, chloride and alkaline values during clinical improvement.


Melanocyte pattern of an area of freckled epidermis covering a stretched scar.


The effect of inhibition of non-specific cholinesterase on perception of tactile sensation in human volar skin.


An American philosophy of financing health care costs.


Hazards of the newborn.

Hazards of the newborn.


A review of Q fever; with a report on a recent human case in Iowa.


Cervical disease; diagnosis, management and the role of major surgery.


The Knowles vertebral support operation.


Partnership life insurance.

Partnership life insurance.


Blue shield states its case.

Blue shield states its case.


Trends in the malpractice field.

Trends in the malpractice field.


Medical considerations in cancer surgery of the aged.


Asiatic influenza in a midwestern town: with a comparison of intradermal and subcutaneous vaccination.


Relaxin; its use in normal obstetrics.

Relaxin; its use in normal obstetrics.


Cerebrospinal fluid rhinorrhea: from a temporal bone defect.


The history of medicine in Clay County, Iowa.


Tebanyl: a clinical trial.

Tebanyl: a clinical trial.


Hyperbilirubinaemia in the premature.

Hyperbilirubinaemia in the premature.


Report on a trial of tebanyl in cases intolerant to PAS.


PAS in urine.

PAS in urine.


In memoriam: Michael O'Hea.

In memoriam: Michael O'Hea.


A case of hyperemesis gravidarum with (?) acute yellow atrophy.


THE ARTIFICIAL kidney.

THE ARTIFICIAL kidney.


A survey of accidents in old age.

A survey of accidents in old age.


Chlorothiazide: an effective diuretic.

Chlorothiazide: an effective diuretic.


In memoriam: Dr. John Cahill.

In memoriam: Dr. John Cahill.


Oral diuril; study of its use in treatment of arterial hypertension.


Evulsion of tendons; report of unusual case.


Realistic medical evaluations; criteria for employment of the physically handicapped.


Economics in medicine.

Economics in medicine.


Leriche syndrome; report of two cases occurring in brothers.


SOCIAL security; the physician's role in the disability program.


BCG after 35 years; a disaster or a triumph?


Diabetic detection drive: the results and their implications.


The diabetic's diet and his income.

The diabetic's diet and his income.


Oral hypoglycemic agents: their uses and limitations.


The diabetic triopathy.

The diabetic triopathy.


The management of diabetic acidosis.

The management of diabetic acidosis.


Diabetes and pregnancy.

Diabetes and pregnancy.


Meprobamate as a pretreatment drug for electroshock treatment.


The treatment of diabetic patients with surgical problems.


Experiences with the surgical treatment of aneurysms of the abdominal aorta.


The staphylococcal problem today.

The staphylococcal problem today.


Cryptococcus meningitis.

Cryptococcus meningitis.


The allergic child.

The allergic child.


Effect on portal blood ammonium of administering nitrogenous substances to patients with chronic hepatic disease.


A simple new method for estimating cardiac output.


Interrelationship between serum calcium levels: calcium 45 and strontium 85 metabolism in man.


Influence of chelates on the matabolism of radioyttrium (Y90). III.


Kinetic studies of skeletal metabolism by external counting of injected radioisotopes: the radioisotope osteogram.


Effects of heparin on body temperature and plasma lipids following intravenous administration of fat emulsion in man.


On the composition of chyle chylomicrons.


Experimentally induced permanent unilateral renal disease in dogs.


Complement fixation reactions with DNA and leukocyte material in systemic lupus erythematosus: correlation with the L. E. cell phenomenon and the clinical status.


Effect of intravenous fibrinolytic enzymes on the vegetations of experimental bacterial endocarditis.


Clinical usefulness of consecutive four-day I 131 serum levels in thyroid disease.


The erythropoietic simulatory activity of batyl alcohol.


The type-specific reactivity of the influenza complement fixation test: inability of allantoic fluid antigens to distinguish between Asian and other recent type A influenza virus infections.


Evidence that glass increases plasma PTA activity.


Deletion of plasma thromboplastin factor D deficiency.


Studies involving fat utilization in traumatized rats.


Studies on the normal serum panagglutinin active against trypsinated human erythrocytes. IV. The presence of normal serum panagglutinin in patients with congenital agammaglobulinemia.


The ox cell hemolysin test as a diagnostic procedure in infectious mononucleosis.


Concentration of vitamin B12 from urine by adsorption on carbon; a sensitive assay of radiocyanocobalamin in the Schilling test for pernicious anemia.


A simple device for making emulsified vaccines.


A modification of Malkin's screening test for the detection of artifactually high organic iodine compounds in sera.


A method for accurate determination of plasma albumin; comparison of albumin values obtained with three other methods.


Factors in the hypocholesteremic response of patients given a brain extract.


Inhibition of lipemia clearing activity by human white blood cell and platelet components.


Cardiac complications in patients with nontoxic and toxic nodular goiter and with Graves' disease.


Iron enzvmes in iron deficiency. III. Catalase in rat red cells and liver with some further observations on cytochrome C.


Red cell phosphorus and potassium in health and disease.


Determination of ornithine carbamyl transferase in serum.


The measurement of changes in acetylcholine level (ACh) in rat brain following ammonium ion intoxication and its possible bearing on the problem of hepatic coma.


Comparative levels of high molecular weight (19S) gamma globulin in maternal and umbilical cord sera.


Sensitivity of shigellae isolated during 1954 and 1957 to five antibiotics.


Investigations into the source of antibodies to gelatin in normal sera.


Determination of diphtheria and tetanus antitoxin by the hemagglutination test in comparison with tests in vivo.


The simultaneous determination of Cr51 and I 131 activities in doubly labeled blood.


The efficient separation of lymphocytes from normal human blood.


The effect of protamine on thromboplastin generation.


A spectrophotometric method for the determination of Evans blue dye in the presence of hemolysis and turbidity.


A simple, rapid, and accurate method of extracting T-1824 from plasma, adapted to the routine measurement of blood volume.


A simplified micro double-diffusion agar precipitin technique.


The apparent relationship between the Stein-Leventhal syndrome and endometrial carcinoma.


Maternal mortality in North Dakota.

Maternal mortality in North Dakota.


Unusual manifestations of migraine.

Unusual manifestations of migraine.


Scarlet fever.

Scarlet fever.


Treatment of recurrent convulsions in children.


Congenital atresia of the duodenum; twenty-one-year interval report.


Injuries of the urinary tract.

Injuries of the urinary tract.


Curable hypertension.

Curable hypertension.


Observations on prevention of death in the neonatal period.


Premature resort to x-ray therapy; a common error in treatment of carcinoma of the thyroid gland.


Uterus didelphys; a case report.

Uterus didelphys; a case report.


Edward L. Tuohy.

Edward L. Tuohy.


Suppression of lactation with an oral androgenestrogen preparation.


Nursing home care.

Nursing home care.


Fenestration post-mortem histology.

Fenestration post-mortem histology.


Further contribution to the development of the labyrinthine capsule.


Repair of tympanic perforations.

Repair of tympanic perforations.


Some observations on the mole technique for dilating oesophagus strictures.


Ganglioneuroma of the left maxilla and orbit.


Tracheostomy: sudden death from delayed air embolism.


Congenital atresia of external auditory meatus.


Sequestration of the labyrinth.

Sequestration of the labyrinth.


Surgery of congenital atresia of external auditory meatus.


Infectious mononucleosis presenting as massive tumour of nasopharynx with cervical adenitis.


Endaural surgery of the jaw joint.

Endaural surgery of the jaw joint.


Tetanus from a marine sponge.

Tetanus from a marine sponge.


Hearing problems in a baby.

Hearing problems in a baby.


The diagnosis and treatment of thrombosis of the internal carotid artery; report of two cases.


On the criteria for the adequate management of diabetes.


Importance to patient care of a medical education program in nonuniversity affiliated hospitals.


Pulmonary embolism and infarction.

Pulmonary embolism and infarction.


Diuril, a new antihypertensive drug.

Diuril, a new antihypertensive drug.


Diabetes and pregnancy.

Diabetes and pregnancy.


The treatment of bleeding esophageal varices.


The use and misuse of antibiotic combinations.


The management of chronic renal insufficiency.


The surgical treatment of duodenal ulcer.


Principles of electrocardiography and spatial vectorcardiography.


Experience with methylphenidate hydrochloride (ritalin).


World peace through medicine.

World peace through medicine.


Allergy to insect venom.

Allergy to insect venom.


Bronchoscopy in the control of tracheo-bronchitis.


Psychiatric intensive treatment program in general hospitals.


Lumbodorsal splanchnicectomy in the treatment of essential hypertension.


The treatment of vaginitis with a new nitrofuran combination.


The staphylococcal disease problem.

The staphylococcal disease problem.


Shock of cardiovascular origin.

Shock of cardiovascular origin.


Acute intermittent porphyria.

Acute intermittent porphyria.


Surgery of the prostate emphasizing one-step suprapubic prostatectomy.


A ritual for diagnostic uterine curettage.


Extensive pulmonary candida albicans with recovery.


Clinical studies on a new cod liver oil preparation.


The effects of general anesthesia on the circulation.


The lawyer and doctor in court.

The lawyer and doctor in court.


Diagnosis and treatment of intraoral cancer. I.


A VIEW of our family physicians.

A VIEW of our family physicians.


The public health laboratories.

The public health laboratories.


The medical school of the University of Western Australia.


Samuel Bard; 1742-1821.

Samuel Bard; 1742-1821.


Hospitals which do and do not fill their intern quotas; a survey of characteristics.


A psychopharmacology exercise for medical students.


Concerning the history of medicine.

Concerning the history of medicine.


Personality factors among medical students as related to their predisposition to view the patient as a whole man.


Diversity of values and objectives in medical education. A. Some differences among medical schools and medical students.


B. Pediatric lions and gynecological lambs.


C. Vocational choice and career evolution.


D. The effect of medical education on attitudes: a follow-up study.


The implications of diversity.

The implications of diversity.


Educational environment as related to the development of the individual student. A. Treating the medical student as a member of a graduate professional school.


B. The learning process in a school of medicine.


Noncurricular factors affecting the medical student.


B. The invisible psychologist.

B. The invisible psychologist.


Two approaches to student counseling. A. Counselling in medical school via faculty advisers.


Procedures for the sociological study of the values climate of medical schools.


Commentary from medical education on the sociological studies. A. Some implications of the sociological diagnosis.


Traditional vs. novel approaches to medical education.


Development of professional attitudes and capacities.


New directions in programs of medical education.


The student in the British pattern of medical education.


The American University of Beirut School of Medicine.


Postgraduate training of physicians in Poland.


Benjamin Waterhouse, Harvard's first professor of physic.


A survey of the teaching of nutrition in medical schools.


The Canadian student; western style.

The Canadian student; western style.


For my son, now qualified.

For my son, now qualified.


Spurious growth inhibition by antibiotic discs having a lactose base.


A new design for perspex museum jars.

A new design for perspex museum jars.


The comparative susceptibility of various tissue culture cell lines to adenovirus types 1-7.


Quality control.

Quality control.


A laboratory operated syringe service.

A laboratory operated syringe service.


The colloidal gum mastic reaction in experimental trypanosomiasis.


Simplified sodium hydroxide method for the culture of tubercle bacilli from sputum.


An evaluation of the formic acid-ion exchange resin method of bone decalcification.


An improved Petri dish.

An improved Petri dish.


Cancers and precancers of the skin.

Cancers and precancers of the skin.


Mephentermine in myocardial infarction.

Mephentermine in myocardial infarction.


Observations on iproniazid (marsilid) therapy in ambulatory psychiatric patients.


The physician's responsibility in the care of the skin.


Physio-pathology of the capillaries.

Physio-pathology of the capillaries.


Coagulation factors relating to obstetrics and gynecology.


Atopic dermatitis.

Atopic dermatitis.


Treponemal tests in the serodiagnosis of syphilis.


To parents of children with delayed speech development.


General John Beatty (1749-1826): patriot and physician.


SYMPOSIUM on medical care coverage.

SYMPOSIUM on medical care coverage.


Psychosomatic aspects of narcolepsy.

Psychosomatic aspects of narcolepsy.


Confirmation of objective test factors and assessment of their relation to questionnaire factors: a factor analysis of 113 rating, questionnaire and objective test measurements of personality.


Recent advances in the treatment of schizophrenia: group training and the tranquillizers.


Effects of E.C.T. upon psychomotor speed and the distraction effect in depressed psychiatric patients.


The effects of exposure time in immediate recall on abnormal and questionnaire criteria of personality.


Humoral changes in manic-depressive psychosis with particular reference to the excretion of catechol amines in urine.


A controlled study of the prognostic significance of autonomic responses in the chlorpromazine treatment of disturbed psychotic patients.


Discrepancies between factor analysis and multivariate discrimination among groups as applied to personality theory.


Psychoneurotic symptom clusters, trait clusters and psychological tests.


Functional disorganization of the left limbs in a tumour of the corpus callosum infiltrating the hemispheres.


The effects of hypophysectomy on intellectual functioning.


Investigation of a new compound, B.W.203, and of chlorpromazine in the treatment of psychosis.


The relationship between prenatal porencephaly and the encephalomalacias of early life.


Reflections on the teaching of psychiatry.


A test for residual mental ability in senile dementia.


Experimental studies of a perceptual anomaly. VI. The application of the peephole analogy to the perception of organic psychiatric patients.


Dimensional theory applied to schizophrenic patients.


Hysteria; a re-evaluation.

Hysteria; a re-evaluation.


The seventieth birthday of R. Gjessing.

The seventieth birthday of R. Gjessing.


An investigation into the therapeutic action of hydroxyzine (atarax) in the treatment of nervous disorders and the control of the tobacco-habit.


Clinical trial with trinuride.

Clinical trial with trinuride.


Psychiatric and electro-encephalographic studies in socially adjusted old people.


Hepato-splenomegaly complicating one out of 4 case of Laurence-Moon-Biedl syndrome in a group of seven siblings.


The incidence of cutis verticis gyrata in three low-grade mental defectives.


Assessing a new phenothiazine.

Assessing a new phenothiazine.


Physical treatment for schizophrenia.

Physical treatment for schizophrenia.


The effects of physical treatment on some psychological functions.


MC4703: a new phenothiazine derivative.

MC4703: a new phenothiazine derivative.


A clinical trial of stemetil (prochlorperazine).


Calcium, phosphate and phosphatase in mongolism.


Suicidal behaviour in depressive illness; a study of aetiological factors in suicide.


The pre-diabetic state in man; definition, interpretation and implications.


Diabetic acidosis.

Diabetic acidosis.


The correlation of the fall of blood sugar with the reduction of weight.


The kidney in diabetes.

The kidney in diabetes.


Current status of the oral hypoglycemic agents.


Spontaneous hypoglycemia: its relationship to diabetes mellitus.


Headaches of vascular origin.

Headaches of vascular origin.


Current concepts in the control of urinary tract infections.


The physician's responsibilities in the management of rheumatoid arthritis.


Teenage delinquency.

Teenage delinquency.


ECHO 9 viruses.

ECHO 9 viruses.


Mammary-cancer-inducing and inhibitory inherited hormonal patterns in mice.


The polynuclear aromatic hydrocarbons in cigarettesmoke condensate. II.


Studies on the anemia of tumor-bearing animals. I. Distribution of radioiron following the injection of labeled erythrocytes.


Growth of mouse ascites tumor cells in diffusion chambers. I. Studies of growth rate of cells and of the rate of entry of antibody.


Serum enzymes. II. Glycolytic enzymes in patients with cancer and other diseases.


Serum enzymes. III. The significance of abnormalities of glycolytic enzymes in the serum of cancer patients.


Immunogenetic studies on x-irradiated mice treated with homologous hematopoietic cells.


Validity of determining circumcision status by questionnaire as related to epidemiological studies of cancer of the cervix.


Rate and equilibrium constants for the reaction of maleic anhydride with the methyl-1, 2-benzanthracenes.


Comparative chromosomal studies on mammalian cells in culture. II. Mouse sarcomaproducing cell strains and their derivatives.


Progressions of a reticulum-cell sarcoma of the mouse in vivo and in vitro.


Susceptibility of agent-free inbred mice and their F 1 hybrids to estrogen-induced mammary tumors.


Psychological studies of Korsakoff's psychosis. II. Perceptual functions.


Chlorpromazine in schizophrenic withdrawal and in the withdrawn schizophrenic.


Investigations of the urinary excretion pattern in psychotic patients.


Psychological implications and effects of insulin therapy.


Clinical and pharmacological studies of marsilid and theoretical considerations concerning its antidepressant action.


The schizophrenic's vulnerability to the therapist's unconscious processes.


Human values in medical education.

Human values in medical education.


A note on first admissions of the aged to mental institutions.


NEUROPATHOLOGY in Western Europe.

NEUROPATHOLOGY in Western Europe.


The relationship between edema, blood-brain-barrier and tissue elements in a local brain injury.


Encephalitis presumably of viral origin, associated with massive necrosis of the temporal lobe.


Importance of ischemic damage to small vessels in experimental cerebral infarction.


On the nature of pigment granules in the cells of the locus coeruleus and substantia nigra.


Intracranial teratoma of a newborn; report of an unusual case.


Tumorforming atypical amyloidosis of the choroid plexus with invasion of the cerebral white matter.


Acid fuchsin convulsions and electroshock in the mouse.


A note on lipase and allergic meningoencephalomyelitis.


The nonspecific lesions of Hallervorden-Spatz disease; a histochemical study.


Persistent carotid-basilar anastomosis; report of a case.


The morphology of meningiomas grown in culture.


Piloid gliosis; a histological study.

Piloid gliosis; a histological study.


The nervous system in trichloroethylene intoxication; an experimental study.


Spinal cord granuloma due to Schistosoma haematobium; report of one case.


The amino acid adequacy of milo (grain sorghum) for the growth of rats.


Significance of dietary zinc for the growing chicken.


Effect of thyroprotein and penicillin on the thiamine requirement and growth of normal and hyperthyroid rats.


Production and study of vitamin E deficiency in the baby pig.


A study of the effect of deoxypyridoxine or isoniazid upon mineral retention and liver enzyme activities of pyridoxine-deficient male rats.


Studies of the metabolizable and productive energy of glucose for the growing chick.


An unidentified factor in alfalfa which counteracts mineral oil toxicity in the rat and mouse.


Nutrition of salmonoid fishes. VI Protein requirements of chinook salmon at two water temperatures.


Studies of the nutritive effects of selenium for chicks.


Essential fatty acid deficiency. I. Content of polyenoic acids in testes and heart as an indicator of EFA status.


Wheat cereal diets, rat caries, lysine and minerals.


The vitamin B12 content of Azotobacter vinelandii.


Henry Albright Mattill (November 28, 1883-March 30, 1953).


Estimated dietary intake, urinary excretion and blood vitamin C in women of different ages.


Effects of thiamine and riboflavin deficiency on histidine metabolism.


The absorption of vitamin A in dogs following cholecystonephrostomy.


The role of bile in calcium absorption.

The role of bile in calcium absorption.


Effects of supplementary methionine and choline on tissue lipides and on the vascular structure of cholesterol-fed growing rats.


The dental caries response of rats fed cariogenic and non-cariogenic diets for different periods of time.


Dental caries in two strains of rats fed diets of two degrees of fineness.


Nutritive value of differently processed groundnut meals and the effect of supplementation of the meals with amino acids, antibiotics and vitamin B12.


Gastric emptying and intestinal absorption of carbohydrate and protein as influenced by the nature of the test meal.


Electrophoretic analyses of groundnut proteins prepared under different conditions of extraction of oil.


Pregnancy toxaemia associated with hydrops foetalis, hydatidiform mole and hydramnios.


Thecal and allied reactions in epithelial ovarian tumours.


The histogenesis of ovarian tumours.

The histogenesis of ovarian tumours.


The effect of penicillin, aureomycin, streptomycin and vitamin B12 on the liver reserves of vitamin A esters of the rat.


Recurrent pregnancy toxaemia.

Recurrent pregnancy toxaemia.


Lipoid masculinizing tumours of the ovary; with a report of a case.


Primary amenorrhoea as a manifestation of pelvic tuberculosis.


Living births following drug therapy for infertility associated with proven genital tuberculosis.


Tubal pregnancy after treatment of genital tuberculosis.


Infant mortality in Northern Nigeria, with especial reference to the Birom Tribe.


Occult blood in the vagina as an early sign of organic genital conditions after menopause.


A study of obstetric results in an under-developed community. I. The objects, materials and methods of the study; some comparative rates.


A study of obstetric results in an under-developed community. II. The incidence and importance of certain factors with bearing on obstetric death rates.


The placental septa; a study based upon nuclear morphological sex differences.


Volvulus complicating pregnancy and the puerperium.


Experience with new contrast media for hysterosalpingography.


A case of placenta praevia percreta with additional unusual features.


Studies of the oxygen consumption of fresh placental tissue from normal and abnormal pregnancies.


A study of the vessels of the placental bed in normotensive and hypertensive women.


A case of chronic inversion of the uterus.


Pregnancy in association with Crohn's disease.


A case of massive endometrial hyperplasia associated with prolonged stilboestrol administration.


Subcutaneous fat necrosis of the newborn.


Acroparaesthesia in pregnancy and the carpal tunnel syndrome.


Standards in obstetrics; a plea for uniform standards in maternity statistics and hospital reports.


THE OBSTETRIC Medicine Research Unit, Aberdeen.


The deleterious effects of adrenocorticoids in tuberculosis; report of three cases.


A review of the propagation of the nerve impulse at the myonerual junction and factors affecting transmission.


Research into the dynamic nature of the human fovea-cortex systems with intermittent and modulated light. I. Attenuation characteristics with white and colored light.


Research into the dynamic nature of the human fovea-cortex systems with intermittent and modulated light. II. Phase shift in brithtness and delay in color perception.


Effect of stereoimage decentration on apparent size.


Note on stereoscopic acuity and observation distance.


Study of visual acuity during the ocular pursuit of moving test objects. I. Introduction.


Study of visual acutiy during the ocular pursuit of moving test objects. II. Effects of direction of movement, relative movement, and illumination.


New technique for the measurement of small eye movements.


Needs and values of a hospital dental service.


Clinical and histological study of alveolar osteitis.


Plastic procedures as applied to oral surgery.


Periapical fibrous dysplasis (cementoma).