Ocular toxoplasmosis.

Ocular toxoplasmosis.


Photocoagulation of the retina: report of a successfully treated case of angiomatosis retinae.


Attitudes in psychiatric activity therapy.


The adhesion of the lens capsule to the hyaloid membrane and its relation to intracapsular cataract extraction.


A dynamic therapy for schizophrenia.

A dynamic therapy for schizophrenia.


Aqueous humor dynamics: the effect of pentolinium (ansolysen) on normal human eyes.


Primary tumors of the orbit; with case reports.


A clinical and pathologic study of exfoliation of the lens capsule.


Not Available.

Not Available.


Angiomatosis retinae, eleven years after diathermy coagulation.


Occupational therapists as specialists in mental hospitals.


Experimental implants of sclera into the anterior chamber.


A leather punching device adapted to the drill press.


Penetrating keratoplasty: observations based on a series of 148 cases with special emphasis on techniques of graft fixation.


An intensive activities program for chronic neuropsychiatric patients.


Surgery for senile macular degeneration.


DeWecker scissors in removing corneal-scleral sutures.


White spots of the iris.

White spots of the iris.


Moist chamber.

Moist chamber.


Corneal graft table.

Corneal graft table.


Collated near-vision test card.

Collated near-vision test card.


Supplemental intravenous analgesia for cataract surgery.


Utilizing science experiences in a pediatric program.


Tubocurarine and nembutal anesthesia.

Tubocurarine and nembutal anesthesia.


Interesting pediatric syndromes.

Interesting pediatric syndromes.


Surgical treatment of scleromalacia perforans.


Prevention of angle-closure glaucoma.

Prevention of angle-closure glaucoma.


Italian ophthalmology.

Italian ophthalmology.


Prescribing for multiple visual needs.

Prescribing for multiple visual needs.


The prognosis in strabismus.

The prognosis in strabismus.


An evaluation of the Children's Visual Achievement Forms at grade I.


Near point diagnosis and visual training with the prism reader.


Visual problems in reading and optometric limits.


The changing concept in ophthalmic styling and dispensing.


The diffuse intimal thickening of the human aorta with aging.


Effects of antihypertensive treatment on the evolution of the renal lesions in malignant nephrosclerosis.


The effects of staphylococcal toxin on the lungs of rabbits.


Pulmonary capillary proliferation induced by oxygen inhalation.


Pilzatropine, the ambiguous alkaloid.

Pilzatropine, the ambiguous alkaloid.


Guardianship.

Guardianship.


Limitations in the chemical treatment of 5461 cases of Hodgkin's disease.


The immunization of children.

The immunization of children.


Some notes on peyote (Lophophora williamsii).


Further studies on germicide-cell surface and germicide-enzyme reactions employing low temperatures.


Herpes simplex.

Herpes simplex.


Intrinsic periodicity of the pontile pneumotaxic mechanism.


Slowly changing bioelectric potentials associated with the blood-brain barrier.


Reticular formation interactions.

Reticular formation interactions.


Spreading depression of activity in amphibian retina.


Resting metabolism of immature nerve fibers in the developing chick.


The diffuse adrenal lesion in Cushing's disease; histologic observations on surgically removed adrenals in four cases.


Permeability of smooth muscle.

Permeability of smooth muscle.


Iron storage. I. The influence of time on the redistribution of excess storage iron.


Exchange of electrolytes in smooth muscle.


Ventricular echoes.

Ventricular echoes.


Antagonistic effects of acetylcholine and nicotine on isolated frog hearts.


Effect of exercise on number of myofibrils per fiber in sartorius muscle of the rat.


Enhanced susceptibility of proliferating endothelium to salivary gland virus under naturally occurring and experimental conditions.


Follicular lipidosis of the spleen; a study of the mode of lipid transport with reference to the lymphatics of the spleen.


Isothiocyanate compounds as fluorescent labeling agents for immune serum.


Comparative effects of DL-thyronine, L-triiodothyronine and L-thyroxine on the isolated perfused frog heart.


Action of serotonin on conversion of fibrinogen to fibrin.


Effect of hemorrhage on red cell and plasma volume of various organs of the dog.


Effect of intravenous blood thromboplastin intermediates on clotting in rats.


Critical role of arterial pressure during hemorrhage in the dog on release of fluid into the circulation and trapping of red cells.


Lipoblastomatosis: a tumor of fetal fat different from hibernoma; report of a case, with observations on the embryogenesis of human adipose tissue.


Melioidosis: pathogenesis and immunity in mice and hamsters. II. Studies with avirulent strains of Malleomyces pseudomallei.


The histogenesis of acute hemorrhagic pancreatitis in dogs.


Effect of sodium in take level on hypertensive disease in rats.


Competition between human plasma albumin and globulins for estradiol and sodium estrone sulfate.


Effect of environmental temperature on diurnal variation of blood constituents in the bovine.


Effect of hypothermia on tubular transport mechanisms.


Effect of change in renal venous pressure upon renal vascular resistance, urine and lymph flow rates.


Effect of change in flow rate upon renal vascular resistance.


Oxygen pressure in urine and its relation to intrarenal blood flow.


Renal tubular chloride reabsorption in the dog during rapidly changing plasma chloride concentration.


Alteration of renal response to carbonic anhydrase inhibitor by synthetic adrenal steroids.


Investigation of mechanism of diuresis produced in the rat by an intravenous infusion of isotonic solution of sodium chloride.


Influence of morphine on urinary corticoid excretion by guinea pigs following exposure to cold and administration of pitressin.


Graphical placement of transport segments along the nephron from urine concentration pattern developed with stop flow technique.


Effect of prior injections of HgCl2 on renal pickup of mercury from subsequent injections.


Serum lipoprotein and cholesterol changes in nephrectomized dogs maintained by peritoneal dialysis.


Dietary cholesterol and adrenal regulation of plasma lipids.


Ovulation induced by hypothalamic stimulation in the anesthetized rat.


Effect of diet on rate of choline oxidation in the hyperthyroid rat.


In vitro inactivation of three naturally occurring estrogens by liver from fetal, newborn, day-old and adult rats.


Source of excess plasma cholesterol in phosphatide-induced hypercholesteremia.


Bile acid-lipoprotein relationships using cholic acid-24-C141.


Distribution of intrinsic factor' activity.


Excretion of free histamine in urine during gastric secretion stimulated by humoral mechanisms.


Gastric secretion and free histamine in urine.


Effect of certain histaminase inhibitors on gastric secretion.


Gastrointestinal changes in the rat on realimentation.


Effect of amphenone on gastric secretory activity.


Ventilatory responses during muscular activity in normal, thyroidectomized and thyroxinized rats.


High energy phosphates during hibernation and arousal in the ground squirrel.


Comparisons of some fluctuations in cosmic radiation and in organismic activity during 1954, 1955 and 1956.


Inhibition of uric acid biosynthesis in birds by o-diazoacetyl-L-serine (azaserine) and 6-diazo-5-oxo-L-norleucine (DON).


Summating potentials of the cochlea.

Summating potentials of the cochlea.


Cortico-spinal responsiveness during EEG arousal in the cat.


Central nystagmus. II. Relationship between central and labyrinthine nystagmus.


Role of food consumption in the mortality response of irradiated rats subjected to prolonged cold exposure.


Warmth discrimination in the dog after a hypothalamic ablation.


Comparison of tissue respiration in mice exposed to heat and cold.


Metabolism of unesterified fatty acids (UFA) in normal dogs.


Glycogen metabolism in the isolated liver.


Utilization of glucose, fructose and galactose by scorbutic guinea pigs.


Time relations among metabolic and morphologic 24-hour changes in mouse liver.


Rate of dephosphorylation of adenosinetriphosphate and the isotonic and isometric contraction of glycerol-treated muscle.


Distribution of glutamine metabolizing enzymes and production of urinary ammonia in the mammalian kidney.


Control of secretion from the avian salt gland.


Displacement characteristics of intracellularly accumulated p-aminohippurate in a mammalian renal transport system in vitro.


Some quantitative studies on phlorizin inhibition of glucose transport in the kidney.


Effect of pentobarbital sodium on uptake of PAH by rat kidney cortex slices in vitro.


Rate of change in sodium and potassium excretion after injection of aldosterone into the aorta and renal artery of the dog.


Effect of sodium, chloride and potassium supplementation, with and without diamox, on muscle composition and renal electrolyte excretion in electrolyte-depleted rats.


Phosphaturesis: a direct renal effect of triiodothyronine.


Nature of proteinuria induced by uranium in rats.


Response to rapid water, sodium and dextran loads of intact Ringer's-infused unanesthetized dogs.


Effects of ascites formation on response to rapid water, sodium and dextran loads in intact and diabetes insipidus Ringer's-infused dogs.


Effects of thyroid hormones on ring A reduction cortisone by liver.


Growth of normal and thyroidectomized rats on iodine-deficient diet.


Cardiac hypertrophy in rats and mice given 3, 3', 5-triiodo-L-thyronine orally.


Pineal blood content and its experimental modification.


Surface activation of guinea pig ventricle determined by intracellular electrodes.


Effect of anesthetization of A-V node on ventricular fibrillation following acute coronary arterial occlusion.


Mechanism of arterial pressure response to histamine-liberators.


Effects of CO2, bicarbonate and pH on the performance of isolated perfused guinea pig hearts.


Effect of interruption of coronary circulation on metabolism of the arrested heat.


Oxygen dissociation curves of mammalian blood in relation to body size.


Effect of atrial systole on ventricular pressure at variable P-Q intervals.


Changes in cardiac contractility during immersion hypothermia.


Effect of artificially controlled heart rate on the incidence of ventricular fibrillation in hypothermia.


Hemostasis in dogs with heart-lung bypass circulation.


Aorta electrolytes of hypotensive potassium-deficient rats.


Failure of change in extracellular volume to alter plasma potassium concentration.


Potassium tranfer kinetics in the isolated dog heart; influence of contraction rate, ventricular fibrillation, high serum potassium and acetylcholine.


Filtration coefficient of the capillaries of the brain.


Effect of anesthesia and hepatic sampling site upon hepatic blood flow.


Response of estimated hepatic blood flow to graded hemorrhage and the infusion of levarterenol.


Effectiveness of levarterenol during hemorrhagic hypotension.


Oxidative activity of aortic tissue of man, the rabbit and the dog with special reference to succinic dehydrogenase and cytochrome oxidase.


pH, Carbon dioxide, oxygen, hemoglobin and plasma electrolytes in blood of pregnant goats and their fetuses.


Leucocyte agglutinating systems.

Leucocyte agglutinating systems.


Binding and transport of serotonin in rabbit blood platelets and action of reserpine.


Effect of potassium on ion transport and bioelectric potentials of frog gastric mucosa.


Electrical activity of the small intestine with special reference to the origin of rhythmicity.


Absorption of cholesterol esters in the lymph-fistula rat.


Effect of derivatives and inhibitors of histamine metabolism on gastric secretion.


Histamine metabolizing activity of dog stomach and intestine.


Acid secretory responses to histamine and the parietal cell mass in the dog.


Anogenital pruritus.

Anogenital pruritus.


The role of the proctologist in nutrition.


Endometriosis in colo-proctology.

Endometriosis in colo-proctology.


Primary carcinoma of the appendix.

Primary carcinoma of the appendix.


Avoiding colostomy in colon surgery.

Avoiding colostomy in colon surgery.


Ano-rectal and related fistulas.

Ano-rectal and related fistulas.


Research in state mental hospitals.

Research in state mental hospitals.


Appraisal of the tranquilizers and their influence on other somatic treatments in psychiatry.


Psycho-physiologic evaluation of phenyltoloxamine, a new phrenotropic agent; a comparative study with reserpine and placebo.


Psychiatric occupational therapy: some aspects of roles and functions.


Action of methyl-phenidylacetate (ritalin) and reserpine in behavior disorders in children and adults.


Psychiatric aspects of training for honorable survival as a prisoner of war.


Atropine-like poisoning due to tranquilizing agents.


Mental symptoms as phenomena of agnosia, apraxia, and aphasia.


Seasonal variation in the incidence of severely crippling mental disorders.


Delayed complications of ECT crush syndrome: report of a fatality.


Multiple self concepts as effected by mood states.


Regressive EST, chlorpromazine, and group therapy in treatment of hospitalized chronic schizophrenics.


TP-21, a new phenothiazine.

TP-21, a new phenothiazine.


On special uses of diphenhydramine hydrochloride in the somatic therapy ward of a psychiatric hospital.


Note on methoxydone (AHR-233).

Note on methoxydone (AHR-233).


Senescent memory decline and senile amnestic syndrome.


Clinical confirmation of Heistad's predictions.


Trifluoperazine in the treatment of psychotic patients.


The effect of dextrose, fat emulsion and amino acids on the rate of disappearance of alcohol in the blood.


Deaner an adjunct for treatment of schizoid and schzophrenic patients.


Dr. Blain: an appreciation.

Dr. Blain: an appreciation.


CHANGING roles of hospitals for psychiatric treatment.


Childhood patterns predictive of adult schizophrenia: a 30-year follow-up study.


An approach to the problem of homosexuality in the military service.


Iproniazid chemotherapy in melancholia.

Iproniazid chemotherapy in melancholia.


The semantics of psychotherapy.

The semantics of psychotherapy.


An explanation for transference cure: its occurrence in psychoanalysis and psychotherapy.


Brain damage, mental retardation and childhood schizophrenia.


Schizophrenic symptomatology in mentally retarded children.


Studies of parental deprivation in psychiatric patients.


Termination of chlorpromazine with schizophrenic patients.


Specific behavioral changes produced by chlorpromazine in chronic schizophrenia.


Trilafon in the treatment of chronically psychotic hospitalized patients.


Atropine coma: a somatic therapy in psychiatry.


The treatment of depressive states with G 22355 (imipramine hydrochloride).


Observations on the comparative effects of tranquilizers on patients previously treated with prochlorperazine.


Comparison of effects of normal and schizophrenic serum on motor performance in rats.


An investigation of the validity and reliability of the Akerfeldt test.


Aortic homograft surgery and electroshock.


Addiction to glutethimide (doriden).

Addiction to glutethimide (doriden).


Non-restraint.

Non-restraint.


Ethics and psychology.

Ethics and psychology.


Ego mastery and the therapeutic process.


Various methods of psychotherapy and their functions.


The dream process.

The dream process.


Two approaches to human relations.

Two approaches to human relations.


Some approaches to and problems in the treatment of child disturbances.


Some observations on psychotherapy with patients suffering from neoplastic disease.


Transactional analysis: a new and effective method of group therapy.


Irrational psychotherapy: an appeal to unreason. III.


Psychotherapy and adjunctive means in psychiatry; case presentation and discussion.


A workshop in self-understanding designed to prepare patients for psychotherapy.


Preventive psychiatry in community action; introduction.


Psychotherapy with children and preventive psychiatry.


Industrial psychiatry as preventive psychiatry.


Potentials for prevention in a public school setting.


Public education in preventive psychiatry.


Arthropod-borne encephalitis in the U. S. A.


Supplementation of diets with proteins and amino acids.


Sampling and screening problems in a rheumatic heart disease case-finding study.


The effect of chlorine in water on enteric viruses.


The psychology of dietary change.

The psychology of dietary change.


Psychological aspects of obesity in adolescence.


Obesity in the adolescent.

Obesity in the adolescent.


The role and use of codes for compiling service statistics.


Development, application, and evaluation of the Wayne County public health nursing record system, with an analysis of the statistical method used.


Inquiry into diagnostic evidence supporting medical certifications of death.


Applications of order statistics to health data.


Sequential methods in clinical trials.

Sequential methods in clinical trials.


Urologic roentgenology: some clinical applications.


Pyelographic diagnosis of lesions of the renal papillae and calyces in cases of hematuria.


A classification of the urographic patterns in children with congenital bladder neck obstruction.


The roentgen manifestations of carcinoma and cyst in the same kidney.


The intravenous urogram in acute leukemia.


Kidney size in acute leukemia.

Kidney size in acute leukemia.


Simultaneous cholecystography and urography with a new medium duografin.


Ureterocele: roentgenologic diagnosis with report of an unusual case.


A safe contrast medium for urethrography.


Thixokon cystourethrography.

Thixokon cystourethrography.


Roentgenographic manifestations in a severe case of alkaptonuric osteoarthritis.


Enlargement of the placenta as demonstrated by soft tissue placentography.


Pelvic angiography; with particular reference to its value in intrauterine pregnancy after the fifth month of gestation.


The roentgenologic interpretation and uses of percutaneous retrograde pelvic arteriography.


Deuel's halo sign.

Deuel's halo sign.


The prenatal roentgen diagnosis of fetal hydrops.


Traumatic rupture of the gravid uterus.

Traumatic rupture of the gravid uterus.


Gartner's duct.

Gartner's duct.


An evaluation of the somatic and genetic hazards of the medical uses of radiation.


Reduction of radiation hazard in obstetric roentgenography.


The interrelationship of obstetric, gynecologic, and urologic problems.


Radioactivity and the human skeleton.

Radioactivity and the human skeleton.


Cancer of the breast: a study of short survival in early cases and of long survival in advanced cases.


Neuroblastoma originating from olfactory epithelium (esthesioneuroblastoma).


Carcinoma of the nasal fossa.

Carcinoma of the nasal fossa.


Radiation therapy for cancer of the tonsil.


Carcinoma of the palatine tonsil.

Carcinoma of the palatine tonsil.


Radiation therapy of carcinoma of the pancreas: report on 91 cases.


Roentgen treatment of granulosa cell carcinoma of the ovary.


Liposarcoma: case reports and discussion of its pathology, diagnosis and treatment.


Cardiac metastasis from squamous cell carcinoma of the skin of the nose: report of a case.


Metastatic malignant melanoma of the kidney simulating a primary neoplasm: a case report.


The vertebral pedicle sign: a roentgen finding to differentiate metastatic carcinoma from multiple myeloma.


Recent experimental contributions to radiotherapy.


Tumor response to ionizing rays at elevated temperatures: a review and discussion.


Localized roentgen-ray beam irradiation of the hypophysohypothalamic region of guinea pigs with a 2 million volt Van de Graaff generator.


Radiation characteristics of a kilocurie revolving cobalt 60 therapy unit.


Etymologic and other aspects of palliation.


Recognition of hyperparathyroidism.

Recognition of hyperparathyroidism.


Injuries to the head.

Injuries to the head.


Paraplegia associated with hyperextension injury to the cervical spine.


Intervertebral disc removal and spine fusion.


Skin suture marks.

Skin suture marks.


Hemangiopericytoma.

Hemangiopericytoma.


Emotional reactions of surgical patients to hospitalization, anesthesia and surgery.


Orthopedic aspects of congenital hypertrophy.


Analysis of eighty-six cases of intertrochanteric fracture of the femur treated conservatively.


Experimental studies of peripheral arterial embolism in dogs.


Alloplastic repair of defects in the chest wall.


Gastroschisis.

Gastroschisis.


Primary non-specific ulceration of the small intestine.


Ileorectal anastomosis in the treatment of ulcerative colitis.


An operation for an external pancreatic fistula.


The appendix, the tissue committee and the small hospital.


A method of eliminating air bubbles in a bubble-type oxygenator.


A new approach for dorsal cordotomy.

A new approach for dorsal cordotomy.


Kirschner wire fixation of bone plates in craniotomies.


Spontaneous disappearance of pulmonary metastases following nephrectomy for hypernephroma.


Pulmonary resection and closure of acquired benign esophagopulmonary fistula.


Osteomyelitis of the Os calcis following triple arthrodesis.


Fibrosarcoma of the tongue.

Fibrosarcoma of the tongue.


Mucocele of the appendix presenting as a recurring abscess in the right groin.


Amyloidosis of gastrointestinal tract simulating gastric carcinoma.


Duplication of the stomach.

Duplication of the stomach.


Perforation of the cecum complicating adynamic ileus.


Congenital absence of the gallbladder.

Congenital absence of the gallbladder.


The diagnostic corner.

The diagnostic corner.


Case analysis clinic.

Case analysis clinic.


Surgery court cases.

Surgery court cases.


Experimental infections of the bovine genital system with trichomonads from the digestive tracts of swine.


Leptospira canicola infection in a newborn calf.


Experimental leptospirosis. VI. Histopathology of the bovine placenta in Leptospira pomona infections.


Lungworm infections in calves produced by subcutaneous injections of larvae.


Studies on the oral administration of sulfaquinoxaline in dairy cattle; pharmacology and pathology.


Phenothiazine treatment of yearling beeves on winter pastures.


The effect of experimental infection with Ostertagia Ostertagi and Trichostrongylus Axei in calves on weight gain, feed consumption, and feed utilization.


Studies on shipping fever of cattle. I. The experimental exposure of cattle with various cultures of Pasteurella.


Studies on shipping fever of cattle. II. Isolation of pleuropneumonia-like organisms.


Effects of endocrine therapy on the growth of dwarf beef cattle.


Studies on urolithiasis. I. Experimental production associated with feeding in steers.


The effect of chlortetracycline, fed continuously during fattening, on the incidence of liver abscesses in beef cattle.


Cholinesterase activity of bovine blood.


The value of urinalysis in bovine botulism.


The effect of adrenocorticotrophic hormone on the circulating eosinophil level; a possible screening test for adrenal gland function in the cow.


Some aspects of glucose metabolism in calves after prolonged gestation.


Tumors of the bovine acoustic nerve; a report of two cases.


Neural mechanisms in sexual behavior. II. Gross neuroanatomical and correlative neurophysiological studies of the external genitalia of the bull and the ram.


A study of Haemonchus in cattle and sheep.


Morphological and histochemical study on the ovary of the sheep.


Histochemical studies on the uterus of the sheep.


The persistence of a genital Vibrio infection in a herd of sheep after an outbreak of vibrionic abortion.


Chronic copper toxicosis in sheep.

Chronic copper toxicosis in sheep.


Effect of stable iodine on uptake of radioiodine in sheep.


Adrenal cortical adenomata in the goat.

Adrenal cortical adenomata in the goat.


The successful control of hog cholera virus leukopenia with Hemophilus pertussis bacterin.


Inclusion body rhinitis of swine in Maryland.


Comparative histopathology of experimental swine influenza and virus pneumonia of pigs in disease-free, antibody-devoid pigs.


Cross transmission of nematodes of domestic animals. I. Experimental infection of swine with Trichostrongylus colubriformis.


Essential fatty acid deficiency; its role in parakeratosis.


Relative potency of some steroid hormones and related compounds on canine uterine growth.


Effect of adrenaline and sex hormones on the uterine motility of the bitch.


A study of the anesthetic properties of combinations of hexobarbital sodium and thialbarbitone sodium in dogs.


Electrophoretic mobility of canine serum maltase.


The effect of antibiotics on bacteria in semen and on motility and fertilizing ability of chicken spermatozoa.


The isolation and identification of ornithosis infection in turkeys by tissue culture and immunocytochemical staining.


Experimental distemper in mink and ferrets. I. Pathogenesis.


Comparative histology of the kidney of domestic animals.


Ringworm fungi of feral rodents in southwestern Georgia.


Ringworm fungi of large wild mammals in southwestern Georgia and northwestern Florida.


Survival of Brucella abortus, Leptospira pomona, and Vibrio fetus in the Illini variable temperature semen extender at 29 C.


Detection of foot-and-mouth disease antibody in vaccinated cattle by direct complement fixation.


Comparative potencies of tuberculins produced on asparagine and ammonium glutamate mediums.


Stability of the virus of infectious bovine rhinotracheitis.


Serological studies with the virus of vesicular stomatitis. I. Typing of vesicular stomatitis viruses by complement fixation.


The quantitative determination of mercury in animal tissues.


Paper electrophoretic analysis of rabbit serum as an aid in the selection of experimental rabbits.


The influence of antimetabolites on the growth of Newcastle disease virus in chorioallantoic membranes suspended in Tyrode's solution.


The complement-fixation test in the diagnosis of sarcosporidiosis.


The effects of age and temperature on the survival of oocysts of Eimeria stiedae.


The role of antimicrobial agents in sino-pulmonary infections complicating respiratory allergy.


Umbilical hernia.

Umbilical hernia.


The treatment of achalasia of the esophagus (cardiospasm).


Salmonellosis and allied bacterial diarrheal disease.


Psychiatric aspects of head injury.

Psychiatric aspects of head injury.


Diffusion spermicidal times of commercial contraceptive jellies and creams secured in 1956.


Prolonged elevation of serum protein-bound iodine in a case of subacute nonsuppurative thyroiditis.


Successful non-surgical uses of carbazochrome salicylate.


Prolonged excretion of vitamin B12 following its intramuscular injection as a depot preparation.


The influence of Fiberglas-plastic dust on tuberculosis; an experimental inhalation study of two varieties of dust: histopathologic observations.


The supporting structure of immunity in the therapy of tuberculosis.


Silicotuberculosis; results of medical and combined medical-surgical therapy.


The frequency of post-primary pulmonary tuberculosis according to pulmonary arterial pressure.


Local reactivation of the primary tuberculous focus in the lung.


Pregnancy after pneumonectomy for pulmonary tuberculosis; analysis of a collected series of seventy-four pregnancies in the Netherlands.


Antituberculous activity of thiocarbanidin in vitro and in the experimental animal.


A small outbreak of histoplasmosis.

A small outbreak of histoplasmosis.


The arcana of tuberculosis with a brief epidemiologic history of the disease in the U.S.A. IV.


Pulmonary infection with Allescheria boydii; report of a fatal case.


Diffuse interstitial pulmonary fibrosis (Hamman-Rich syndrome); report of three cases.


The role of pneumoperitoneum in the nonsurgical treatment of esophageal hiatal hernia.


Bronchiolar (alveolar cell) carcinoma; failure to cause symptoms for more than twelve years.


Studies of the PAS salt of isoniazid in the treatment of tuberculosis.


Investigations into the role of fungi in pulmonary diseases in India.


Vocational rehabilitation in pulmonary tuberculosis today.


The challenge of tuberculosis today.

The challenge of tuberculosis today.


Dyspnea as a symptom in parkinson's syndrome.


An evaluation of tuberculosis case finding by tuberculin testing and some observations of histoplasmin sensitivity among young school children.


Full-term delivery following major thoracic surgery for tuberculosis.


The effect of glucose on the tuberculin reaction in tissue culture.


Observations on ambulatory tuberculous patients with pulmonary cavities and noninfectious sputum (the open-negative syndrome).


Bacteriologic and clinical significance of the catalase activity of Mycobacterium tuberculosis.


Clinical use of a single daily dose of para-aminosalicylic acid in association with isoniazid.


Effect of single and of double daily doses of para-aminosalicylic acid in tuberculosis of guinea pigs.


Combined cryptococcal and tuberculous meningitis complicating reticulum cell sarcoma.


Transition from open pulmonary tuberculosis to sarcoidosis.


An evaluation of chemotherapy in pulmonary tuberculosis. I. High doses of isoniazid with PAS and pyridoxine.


An evaluation of chemotherapy in pulmonary tuberculosis. II. Daily streptomycin plus high doses of isoniazid with PAS and pyridoxine.


The vital staining method for the rapid estimation of the bacterial count of BCG vaccine.


A semi-synthetic autoclavable medium for a routine tuberculosis laboratory.


Lack of circulating antibodies after BCG immunization as assayed by the globulin titration technique.


The pancreas in experimental tuberculosis: guinea pig inoculation via the intraperitoneal route.


Titration of cord formation as a measure of pathogenicity of wild-type acid-fast bacilli, typical and atypical.


Bacteriotropic activity of isoniazid in the presence of certain other compounds.


Eternal vigilance.

Eternal vigilance.


Single use disposable disc oxygenator for open heart surgery.


Metabolism of isoniazid by Mycobacterium tuberculosis BCG with reference to current theories of the mode of action.


Keratoacanthoma: a benign cutaneous tumors arising in a skin graft donor site.


Ventricular fibrillation during hypothermia: further observations.


A clinical and laboratory comparison of the effects of commonly used vasodilator drugs on arterial diseases.


Gastrojejunal ulcer and gastrojejunocolic fistula.


Unusual complications of biliary tract surgery; their avoidance.


Nasogastric intubation: indications, complications, safeguards and alternate procedures.


An endocrine approach to thyroid cancer.


Oxyphilic granular cell adenoma of the parotid gland: report of a case.


Surgical treatment of diverticulitis.

Surgical treatment of diverticulitis.


Volvulus of the cecum complicating pregnancy; a report of three cases.


The management of thermal burns.

The management of thermal burns.


Mixed tumor of salivary tissue; a harmful misnomer for a carcinoma.


Intestinal obstruction secondary to coconut fibers.


Pilot studies in the treatment of burns in infants and children.


Mesenteric and omental cysts.

Mesenteric and omental cysts.


The influence of malpractice suits on surgery.


Books--and the education of a surgeon.

Books--and the education of a surgeon.


Alveolar cell carcinoma.

Alveolar cell carcinoma.


Buried talent.

Buried talent.


Single adenoma of the thyroid gland.

Single adenoma of the thyroid gland.


Delay in the diagnosis of breast carcinoma.


Esophago-diverticulostomy for stenosis of upper esophagus associated with Zenker's diverticulum.


Sterility of multiple dose vials after repeated use.


Meckel's diverticulum.

Meckel's diverticulum.


Does transfusion citrate cause hemorrhage?


Rehabilitation of the patient with hemiplegia.


Intracranial ependymomas and their surgical treatment.


Changing patterns of surgical practice.

Changing patterns of surgical practice.


The role of simple skin biopsy in uncertain inflammatory carcinoma of the breast.


Carotid cavernous fistulas: diagnosis and surgical management.


Gastric sarcoma.

Gastric sarcoma.


Postoperative difficulties following subtotal gastrectomy.


Surgical trusteeship; a must.

Surgical trusteeship; a must.


Halothane anaesthesia; drip-feed administration in neuro-surgical and other cases.


Pacatal in neurosurgical anaesthesia.

Pacatal in neurosurgical anaesthesia.


Cardiac arrest.

Cardiac arrest.


Anaesthesia for cerebral angiography.

Anaesthesia for cerebral angiography.


Epidural analgesia for prostatectomy.

Epidural analgesia for prostatectomy.


Anaesthesia for orthopaedic day cases.

Anaesthesia for orthopaedic day cases.


Anaesthesia for laryngoscopy.

Anaesthesia for laryngoscopy.


Dihydrocodeine: an investigation into its use in general anaesthesia.


Carbohydrate metabolism: the effects of surgery in a tropical population.


Liver glycogen alterations in anaesthesia and surgery.


Apnoea.

Apnoea.


Collapse from spinal analgesia in pregnancy.


The reticular system and chlorpromazine.


A pharyngeal airway.

A pharyngeal airway.


An aid to halothane administration.

An aid to halothane administration.


A simple halothane drip feed.

A simple halothane drip feed.


A simple humidifier.

A simple humidifier.


Haemostat.

Haemostat.


ANAESTHETIC literature.

ANAESTHETIC literature.


DR. HOWARD BRUCE WILSON.

DR. HOWARD BRUCE WILSON.


The effect of continuous removal of cerebrospinal fluid on cerebrospinal fluid pressure.


Observations on an Afro-South American planorbid.


Endocrine influences upon the growth of the rudimentary gonad of fowl.


Histological and histochemical observations on the armadillo uterus during the delayed and post-implantation periods.


Prenatal development of the skeleton in Long-Evans rats.


The structural and functional unit in the human liver (liver acinus).


Observations on the fine structure of the carotid body.


The histology of vascular terminations in the rabbit's spleen.


A chemical and histochemical study of acid phosphatase in the epididymis of normal, castrate and hormone replaced castrate mice.


Comparative histological studies of the stomach, small intestine, and colon of warm and active and hibernating arctic ground squirrels, Spermophilus undulatus.


Samuel Randall Detwiler, 1890-1957.

Samuel Randall Detwiler, 1890-1957.


A longitudinal study of digital epiphyseal fusion in adolescence.


Effect of vestibular system damage upon cerebellar ataxia in the monkey.


Accessory atrioventricular muscle bundles of the developing human heart.


Further studies on ear and capsule development in Amblystoma.


Transection of the spinal cord in the adult frog.


Experiments on the development of trunk muscles in anura (Rana pipiens).


Origin of thyroidectomy cells.

Origin of thyroidectomy cells.


Comparative anatomy of the extensor digitorum longus in relation to the knee joint.


Inhibition of lens regeneration in newt eyes by isolating the dorsal iris from the neural retina.


A cytological study of the anterior pituitary gland of the normal, gonadectomized and thyroid deficient hamster (Mesocricetus auratus).


Regeneration of the gastric mucosa in the rat.


A hypophysectomized, gynandromorphic, Syrian hamster.


A study of the structure, chemical nature, and development of cementum in the rat.


Studies on the thymus of the mammal. XI. Histochemical studies of thymus, spleen and lymph node in normal and irradiated mice.


Restoration of involuted zymogenic cells in hypophysectomized rats by replacement therapy.


Design in the nervous system.

Design in the nervous system.


Contraction of glycerinated embryonic myoblasts.


Regulation of ovarian response to irradiation by gonadotrophic antiserum.


Effects of thyroxine on chick embryos.

Effects of thyroxine on chick embryos.


Factors influencing symmetry, posture and reduplication of the developing limb of Amblystoma punctatum.


Erythropoietic changes in cortisone-growth hormone treated hypophysectomized rats as related to changes in oxygen need induced by various doses of thyroxin.


Hormonal influences on the gonadotrophin sensitive hypothyroid rat ovary.


Anileridine; an evaluation of its use in anesthesia and in postoperative analgesia.


Facilitation of intravenous medication during surgical procedures.


The light zone of anesthesia.

The light zone of anesthesia.


Radiation safety for the anesthesiologist.


The treatment of barbiturate poisoning with or without analeptics.


Treatment for barbiturate poisoning with or without analeptics.


Intramuscular doses of succinylcholine as an adjunct in anesthesia.


A new three-way valve for anesthesia.

A new three-way valve for anesthesia.


Training aids in anesthesiology.

Training aids in anesthesiology.


The T-piece technique in anesthesia; an examination of its fundamental principle.


Management of anesthesia and hypothermia for open heart surgery with extracorporeal circulation.


Improved laryngoscope blade designed for ease of manipulation and reduction of trauma.


A practical clinical research sign of general anesthesia.


The effect of methyprylon on respiration and the cardiovascular system of man.


Experiences with the autoplastic cutis vascular graft.


Cyclizine lactate (marezine) for post operative control of nausea and vomiting after cataract surgery.


Succinylcholine for cesarean section (a preliminary report).


The management of circulatory disturbances of the inner ear.


Values for serum glutamic oxalacetic transaminase following anesthesia with fluoromar.


Production of an electrolyte-steroid cardiopathy with NaClO4 and its prevention by MgCl2 and KCl.


Clinical uses of functional ascending phlebography of the lower extremity.


Obstetrical anesthesia with ethyl vinyl ether and oxygen.


Variations in protamine titration results in the blood of atherosclerotic patients.


Romance of tropane: chemical affinities and family relationships of the compound.


Uptake and breakdown of catecholamines in vascular tissue.


The neuromuscular blocking action of neomycin: a concern of the anesthesiologist.


Thrombophilia and hydatid arterial embolism.


SKF d-5137 (dimorlin) a new synthetic analgesic: preliminary report.


Effects of topically applied epinephrine, norepinephrine, acetylcholine and histamine on the intermediate circulation of the mouse spleen.


A study of a 1-aryl cyclo hexyl amine for anesthesia.


Clinical evaluation of chlorisondamine (ecolid) in the treatment of hypertension.


Vasomotor responses to external stimuli in paraplegic patients.


Some recent problems concerning the pharmacology of cholinergic function.


The case law of spinal anesthesia.

The case law of spinal anesthesia.


Sublingual heparin in hyperlipemia; a preliminary report.


One-or two-stage operations for management of postphlebitic varicose ulcers?


[Cranial plasties].

[Cranial plasties].


Metaphyseal decalcification of the bone in nephrosis, with reference to its origin.


[Biochemical determination of perchloride-soluble mucoprotein in cystic formations of the ovary].


[Several conclusions after 2 years of cobalt teletherapy].


[Notes on the behavior of the morphological elements of peripheral blood in subjects of neoplasms treated with cobalt teletherapy].


Treatment of grass pollinosis with a single annual injection of emulsified extract. IV.


The prohypertensive and antihypertensive actions of the kidney.


Serum cholesterol, electrophoretic lipid pattern, diet and coronary artery disease: a study in coronary patients and in healthy men of different origin and occupations in Israel.


The nephrotic syndrome in adults: a common disorder with many causes.


The use of impatiens biflora (jewelweed) in the treatment of rhus dermatitis.


Management of complications of allergic rhinitis.


Electron-microscopic studies of reversible glomerular lesions in the adult nephrotic syndrome.


Some recent developments pertaining to pancreatitis.


Fat absorption and pancreatic function in diabetes mellitus.


Intractable asthma caused by aspiration of cork from a nebulizer; a case report.


Hereditary hyperparathyroidism associated with recurrent pancreatitis.


Observations on the influence of medical therapy on portal hypertension in hepatic cirrhosis.


Interpretation of hematologic and serologic findings in the diagnosis of infectious mononucleosis.


The significance of the lupus globulin; nucleoprotein reaction.


Clinical evaluation of benacortol; an antihistamine-steroid mixture useful in the short-term treatment of allergic diseases.


Immunological unresponsiveness.

Immunological unresponsiveness.


Shock and acute abdominal symptoms complicating acute idiopathic pericarditis.


An investigation into environmental influences in bronchial asthma.


Periodic disease: a clinicopathologic study.


Enzymatic mechanisms in allergy.

Enzymatic mechanisms in allergy.


The nature of itching in dermatitic skin.


Nontropical sprue and functioning islet-cell adenoma of the pancreas: report of case.


Hemorrhagic diathesis in carcinoma of the stomach: a case report.


Aneurysmal dilatation of the aortic sinuses in coarctation of the aorta: report of two new cases and review of the literature.


Thrombotic thrombocytopenic purpura: report of a case and review of the literature.


Gaucher's disease in identical twins.

Gaucher's disease in identical twins.


Progressive exophthalmos developing 12 years after thyroidectomy for diffuse toxic goiter.


PROGRESS report; Committee for the study of hospital standards in Medicine.


The chemistry of diuretics.

The chemistry of diuretics.


The renal transport of electrolytes.

The renal transport of electrolytes.


The mechanism of action of mercurial and xanthine diuretics.


The mechanism of diuretic action of the carbonic anhydrase inhibitors.


The mechanism of action of chlorothiazide.


Difficulties in the appraisal of disturbances in fluid and electrolyte metabolism in clinical medicine.


Antiarrhythmic properties of chlorothiazide.


Diuretic therapy of congestive heart failure.


Chlorothiazide in renal disease.

Chlorothiazide in renal disease.


Some effects of chlorothiazide on electrolyte metabolism and its use in edematous states.


Chlorothiazide in liver disease.

Chlorothiazide in liver disease.


Chlorothiazide in hypertensive and normotensive patients.


The use of chlorothiazide in the treatment of edema: a comparison with other diuretic agents.


Chlorothiazide potentiation of ganglionic blockade in patients with hypertension.


Histochemical and microchemical observations on the lipids of the interscapular brown fat of the female vespertilionid bat Myotis lucifugus lucifugus.


Chlorothiazide in hypertension: studies on its mode of action.


New steroid compounds with progestational activity: introduction.


Some biological activities of certain progestogens. I. 17 alpha-Hydroxyprogesterone 17-n-caproate.


Some biological activities of certain progestogens. II. 9-And 12-halo-11-oxygenated progesterones.


Some chemical and biological properties of 19-nor-17 alpha-ethynyltestosterone.


Some biological activities of 17-ethynyl and 17-alkyl derivatives of 17-hydroxyestrenones.


Comparative potency of several progestogenic compounds in a battery of different biological tests.


Biological action of 17 alpha-hydroxyprogesterone 17-n-caproate on the reproductive processes of the rat.


Attempts to induce and maintain pregnancy in prepuberal mice following treatment with 17 alpha-hydroxyprogesterone 17-n-caproate.


Comparative pharmacological and clinical activity of 19-nortestosterone and 17-hydroxyprogesterone derivatives in man.


Effect of 17 alpha-hydroxyprogesterone 17-n-caproate on the reproductive performance of cattle.


Effect of 17 alpha-hydroxyprogesterone 17-n-caproate on growth and fattening of cattle.


Comparative activity of progestational agents on the human endometrium and vaginal epithelium of surgical castrates.


Metabolic effects in man of steroids with progestational activity.


Effect of progesterone on ovarian morphology and on embryonal mortality in pregnant rats, pigs, and sheep.


Histochemical reactions in the human endometrium following administration of 17-ethynylestrenolone.


Effects of various progesterone compounds on the normal preovulatory endometrium as compared with the endometrium in secondary amenorrhea.


A comparative study of the effect of the progestational agents in human menstrual abnormalities.


Effects of certain 19-nor steroids upon reproductive processes.


Effects of progestational compounds on the reproductive processes of the human male.


A new test for efficacy of progestational compounds.


Clinical use of new progestational steroids in fertility.


Clinical application of 17 alpha-hydroxyprogesterone 17-n-caproate.


Effects of norethynodrel on the human endometrium.


High-potency progestational agents in human pregnancy.


Comparison of the endometrial activities in man of anhydrohydroxyprogesterone and 17-acetoxyprogesterone, a new oral progestational compound.


Effect of 17 alpha-hydroxyprogesterone 17-n-caproate on adrenal steroid excretion.


Observations of the role of progestational agents in human gynecologic disorders and pregnancy complications.


Clinical observation on the use of 17-ethynyl-19-nortestosterone in repeated and threatened abortions.


Clinical use of 17 alpha-hydroxyprogesterone 17-n-caproate in habitual abortion.


Clinical use of 17 alpha-hydroxyprogesterone 17-n-caproate in the prevention of premature labor, and its effect upon fetal salvage.


New steroid compounds with progestational activity: summary.


The influence of sulfhydryl groups and their inhibitors on the distribution of radiocobalt in the organs and intracellular organelles of the mouse.


Hodgkin's disease: control & functions of the lymphocyte.


Outline of problems in Hodgkin's disease.


Potentialities of the lymphocyte, with an additional reference to its dysfunction in Hodgkin's disease.


Treatment of human diabetic pregnancies with estradiol valerate and 17 alpha-hydroxyprogesterone 17-n-caproate.


Hodgkin's disease: some problems of lymphocyte production.


Effects of steroids on aspects of the metabolism and functions of the lymphocyte: a hypothesis of the cellular mechanisms in antibody formation and related immune phenomena.


Some properties of lymphocytes in vivo and in vitro.


The thymic lymphocytosisstimulating factor.


Aspects of the reticuloendothelial system studied with the light microscope and electron microscope.


The cytological identity and interrelation of mesenchymal cells of lymphoid tissue.


Some in vitro and in vivo studies on several mesenchymal cell types bearing on the problem of the reticuloendothelial system.


Studies on the functional interrelationship of fibroblasts and ground substance mucopolysaccharides.


Morphology, chemistry, and function of mast cells.


Measurement of the function of the reticuloendothelium.


Cytology of the Sternberg-Reed cell as revealed by the electron microscope.


Evidence for the virus etiology of Hodgkin's disease.


Malignant nucleoli: cytological studies and perspectives.


Advances in the knowledge of the eosinophil in relation to antibody formation.


Etiological considerations in Hodgkin's disease.


The use of germfree animals and techniques in the search for unknown etiological agents.


Results of therapy in Hodgkin's disease.


Two-million-volt x-ray therapy of Hodgkin's disease.


The scope of chemotherapy in Hodgkin's disease.


Genetic concept for the origin of cancer: historical review.


Effects of selection on chemically induced tumors in mice.


Chemically induced carcinomas of the mammary gland and fibrosarcomas with and without selection.


Maternal age selection and chemically induced tumors in mice.


Mammary tumors in agent-free mice.

Mammary tumors in agent-free mice.


Genetic concepts in mammary cancer in mice.


Some aspects of drug resistance in neoplasms.


Malignancy and the genetics of the somatic cell.


Genetic studies on tumor immunity: an analysis of C3H sublines and their tumors.


Role of chromosomes in cancerogenesis, as studied in serial tissue culture of mammalian cells.


Chemically induced imitations of mitotic anomalies common to cancer cells.


Cellular aspects of tumorigenesis.

Cellular aspects of tumorigenesis.


Carcinogenic mutagens.

Carcinogenic mutagens.


Mutations of viruses in relation to normal and abnormal cell function.


Relationships, established and prospective, between viruses and cancer.


Genetic aspects of hormonal influences on cancer.


Evidence from experimentally induced neoplasms relative to the mutation hypothesis of the origin of malignant disease.


Quantitative colonial growth of single mammalian cells.


The aging process and cancerogenesis.

The aging process and cancerogenesis.


Cellular changes induced by radiation.

Cellular changes induced by radiation.


Mammalian cytogenetics and the cancer problem.


Genetic plant tumors in Nicotiana.

Genetic plant tumors in Nicotiana.


Genetic consideration of leukosis tumor growth in poultry.


Studies on human cancer families.

Studies on human cancer families.


Genetics of human cancer: a general survey of methods.


A genetic concept for the origin of melanomas.


The genetic basis of organic form.

The genetic basis of organic form.


Genetics of homeostasis and of senility.


An experimental analysis of the hypothalamic-hypophysial-thyroid relationship in the rat.


Phenaglycodol therapy in cerebral palsy.


Neuritis syphilitica of the olfactory nerve; report of a case.


Studies in sialolithiasis. I. The structure and mineralogical composition of salivary gland calculi.


Nicotine stomatitis of the palate.

Nicotine stomatitis of the palate.


Some principles of vestibular hydromechanics.


An experimental study of auditory threshold acuity in children with cerebral palsy by PGSR and other techniques.


A new surgical technique for the vocal rehabilitation of the laryngectomized patient.


Surgery to the nasal lobule.

Surgery to the nasal lobule.


The changing years: their impact upon the management of paranasal sinus disease.


Carcinoma in situ of the larynx: a ten year study of its histopathological classification, prognosis and treatment.


Bronchoscopic findings in tuberculous children; a fifteen years' study.


The clinical significance of the anatomical arrangement of the paranasal sinuses.


Orbital apex syndrome.

Orbital apex syndrome.


The hydrodynamic origin of aural harmonics in the cochlea.


Destructive labyrinthotomy: study of prognosis of postoperative disability.


Functional changes in inner ear deafness.


Observations on temporary auditory threshold shift resulting from noise-exposure.


Differential diagnosis between otosclerosis and congenital foot-plate fixation.


Pressures of the labyrinthine fluids.

Pressures of the labyrinthine fluids.


The differential diagnosis of vertigo.

The differential diagnosis of vertigo.


Otosclerosis in ten pairs of identical twins; a continuing study.


Prevalence of rheumatoid arthritis in urban and rural populations in South Wales.


Use of the intramuscular route for prednisolone acetate therapy.


Subcutaneous nodules of Still's disease.


Rheumatoid disease in the larynx and lung.


Recurrent attacks of acute rheumatism in school-children.


Rheumatoid arthritis of the cervical spine in the adult.


C-reactive protein rheumatic heart disease.


Comparison of the erythrocyte sedimentation rate, C-reactive protein, serum diphenylamine, and tetrammonium tests in rheumatic fever and rheumatic heart disease.


Value of uricosuric agents and in particular of G. 28 315 in gout.


Involvement of the nervous system by Reiter's syndrome.


The present position of cardiac surgery.


The therapeutic use of radioactive isotopes.


Cytological diagnosis of prostatic carcinoma.


Scientific meeting of the faculty of anaesthetists, on shock and allied phenomena.


IN MEMORIAM: Sir Victor Hurley.

IN MEMORIAM: Sir Victor Hurley.


Inguinal and femoral hernioplasty; the evaluation of a basic concept.


The intestinal factor in irreversible endotoxin shock.


Treatment of short esophagus with stricture by esophagogastrectomy and antral excision.


Hemodynamics of gastric secretion.

Hemodynamics of gastric secretion.


Peptic ulcer following portacaval shunt.


Technical surgical factors which enhance or minimize postgastrectomy abnormalities.


Results of three methods of therapy for massive gastroduodenal hemorrhage; a statistically valid comparison.


Chemotherapy of cancer: regional perfusion utilizing an extracorporeal circuit.


Palladium 103: a new isotope for interstitial implantation at operation.


Investigations of host resistance in cancer patients.


Role of operative stress on the resistance of the experimental animal to inoculated cancer cells.


Congenital arteriovenous aneurysms.

Congenital arteriovenous aneurysms.


Carcinoma of the stomach.

Carcinoma of the stomach.


Relationship of polyps of the colon to colonic cancer.


Radical transthoracic forequarter amputation.


Surgical management of Hodgkin's disease.


Carcinoma of the pancreatico-duodenal area; operability and choice of procedure.


Studies on pyrogenic effect of tubercular matters. II. The effect of somatic proteins on normal and tuberculous rabbits.


Relative concentration of antiproteins, antipolysaccharides and antilipids in tuberculous rabbit sera measured with corresponding bacillary substances.


Serology as an aid for differential diagnosis of tuberculosis and other pulmonary diseases.


Characterization of Streptomyces species.


Further clinical and laboratory studies with novobiocin. I. Treatment of staphylococcal infections in infancy and childhood. II. Novobiocin concentrations in the blood of newborn infants and in the breast milk of lactating mothers.


Treatment of trachoma with erythromycin-sulfacetamide ointment (CT-877).


The treatment of histoplasmosis with amphotericin B (fungizone).


SU-3118 (carbethoxysyringoyl methylreserpate): a placebo study of antihypertensive potency and of side effects.


Sulfamethoxypyridazine, a new long-acting sulfonamide; a study of blood levels in adults with different dose schedules.


Preliminary studies on propionyl erythromycin.


Phospholipide antithromboplastin. II. Preparation and properties.


Stimulation of Avena coleoptile growth by 6-(substituted) thio- and amino-purines.


D-methionine and the biosynthesis of cephalosporin N.


Histamine catabolism by cat liver homogenates.


Molecular complementariness as basis for reactivation of alkyl phosphate-inhibited enzyme.


A study on the Sakaguchi reaction of arginine on filter paper.


Studies on the enzyme lipase in the housefly.


[Rehabilitation of heart and circulatory diseases].


Relationship between in vitro lysine availability and in vivo protein evaluation in milk powders.


Purification and properties of D-glutamic acid oxidase from Octopus vulgaris Lam.


A purification and investigation of tetanus antitoxin.


The irreversible inhibition of monoamine oxidase in vivo.


Inhibition of lysine utilization in bacteria by S-(beta-aminoethyl) cysteine and its reversal by lysine peptides.


On the specificity of biotin in the metabolism of propionibacteria.


The conversion of D-xylose into volatile organic acids by rumen bacteria.


Enzymic and morphological comparison of normal and salt-extracted rat liver mitochondria.


The kinetics of diiodotyrosine metabolism in normal human subjects.


Studies on the metabolism of norepinephrine, epinephrine and their o-methyl analogs by partially purified enzyme preparations.


Studies on absorption and metabolism of propylene glycol distearate.


An investigation of the in vivo hydrolysis and absorption of propylene glycol distearate.


Dielectric properties of hemoglobin. V. Temperature dependence and urea denaturation.


Acetate metabolism: effects of tracer concentration.


Studies on the oxygen and carbon monoxide equilibria of human myoglobin.


Studies on pig liver microsomes. I. Enzymic and pigment composition of different microsomal fractions.


L-alpha-(dicaproyl) lecithin, a water-soluble substrate for lecithinase A and D.


2-Methoxyestriol: a new metabolite of estradiol in man.


Kinetics of homogentisic acid autoxidation.


Biotin and acid synthesis in a higher plant.


Severe infantile hypercalcaemia with special reference to the facies.


Congenital absence of the intrahepatic bile ducts.


Replacement transfusion as a means of preventing kernicterus of prematurity.


Serum transaminase variations in childhood.


A test for coeliac disease.

A test for coeliac disease.


A longitudinal study of the growth and development of prematurely and maturely born children. I. Introduction.


A longitudinal study of the growth and development of prematurely and maturely born children. II. Physical development.


Pancreatitis in young children.

Pancreatitis in young children.


Herpes zoster ophthalmicus in children.

Herpes zoster ophthalmicus in children.


Observations on the bromide partition test in the diagnosis of non-purulent meningitis.


Pneumatosis intestinalis in Chinese children.


Physical development of schoolgirls in Upper Burma.


The prevalence of dental caries in relation to maturity.


Familial dysautonomia.

Familial dysautonomia.


Autopsy findings in a case of pituitary dwarfism.


Insufficient glucuronide formation in the newborn and its relationship to the pathogenesis of icterus neonatorum.


The first arch syndrome.

The first arch syndrome.


Study of the combined action of cobalt with various antibiotics.


Action of ortho-methylcyclizine on auricular arrhythmias.


On the reactivity of the wall of the carotid sinus.


Effects of chlorpromazine and secobarbital on avoidance and escape behavior.


Potentiation of the pressor response to epinephrine and sympathomimetic aldehydes.


The influence of magnesium calcium and strontium ions of a mammalian nerve-muscle preparation.


Neuropharmacological study of the central effects of benactyzine and hydroxyzine (cerebral electrical activity, alarm and flight reaction on hypothalamic stimulation, central antagonisms).


Bioassay of potential tranquilizers and sedatives against audiogenic seizures in mice.


New studies on aerosols. III. Production of solid, small-sized, aerosols.


New studies on aerosols. IV. Effect of fine dust particles on excised guineapig's lung before and after sympathomimetic aerosols.


New studies on aerosols. V. Antagonistic effects of a sympathomimetic aerosol on the spontaneous collapse of guinea-pigs' excised lungs.


Testosterone and the pituitary I.C.S.H.-content of male and female rats; with additional remarks on body growth.


A new method for continuous measurement of cardiac output.


Experimental studies on burns. LI. Renal effect of chlorothiazide on the burned dog.


A study of pharmacological influences on ultraviolet erythema in guinea pigs.


A comparison of the analgesic and respiratory effects of dihydrocodeine and morphine in man.


Observations on the mechanism of blood pressure changes following chlorpromazine administration in the cat.


Possible explanation of acetylcholine and histamine concentration-action curve.


Studies on chemical protection against the lethal action of parathion.


Effect of prolonged administration of high dose of testosterone propionate on the adrenal cortex of young male rats.


Effect of lidocaine on kidney function in dogs and normal human subjects.


Effect of testosterone propionate on the carbohydrate metabolism in the liver and muscle of male rabbits.


The influence of some nonbarbiturate depressants on central polysynaptic mechanisms.


Emergency lung resection due to a massive hemoptyses in an infant with lung abscess.


Listeria meningitis in infancy; a report of two cases.


Amyoplasia congenita; review of literature and report of three cases.


EDWARD JENNER 1749-1823.

EDWARD JENNER 1749-1823.


Clinical study of the use of a new cerumenolytic agent in children.


Neomycin toxicity: a case report.

Neomycin toxicity: a case report.


Trochanteric bursitis: diagnostic criteria and clinical significance.


Evaluation of pressure as a factor in the production of ischial ulcers.


A method for the quantitative measurement of spasticity and its response to therapy.


Vocational status following chemopallidectomy and thalamectomy for Parkinsonism. I. The problem and initial findings.


Use of hip abduction braces in adults: preliminary report.


[Remarks on the so-called spontaneous tympanoplasty].


The value of endometrial cultures in the diagnosis of endometritis.


Respiratory allergy and environment control.


Hydatidiform mole: a report of four cases.


Rehabilitation means referral.

Rehabilitation means referral.


Hiroshima and Nagasaki.

Hiroshima and Nagasaki.


Thyroid and thyroid cancer.

Thyroid and thyroid cancer.


The use of penicillin V in acute respiratory infections of childhood.


Use of synthetic oxytocin in the management of the third stage of labor.


ALEXANDER MACKENZIE TUTHILL, 1871-1958.

ALEXANDER MACKENZIE TUTHILL, 1871-1958.


[Taxonomic interrelation of virus & bacteria].


[Ganglionic blocking agents in the treatment of arterial hypertension].


[Adenocarcinoma developed from adenoma of the large intestine: anatomical & pathological study].


Two-year comparative study of serial hemagglutination tests done on groups of rheumatoid arthritis patients.


Familial occurrence of the rheumatoid factor.


Clinical studies of seven patients with rheumatoid arthritis and uniquely large amounts of rheumatoid factor.


Chromatographic and electrophoretic studies of the L.E. factor.


Observations concerning the reactivity of normal and rheumatoid gamma globulins in rheumatoid serologic reactions.


Studies concerning the relationship of phenylbutazone to pituitary-adrenal cortical function and metabolism of 17-hydroxycorticosteroids.


Periarteritis nodosa, limited to skin and muscle: report of a case with a discussion of the practical and theoretical implications.


A correlation of constitution and carcinogenic activity. I. A study of the essential molecular parameters.


Intrapulmonary gas mixing studied by the closed-circuit helium technique. I. Theoretical considerations and model lung experiments.


Intrapulmonary gas mixing studied by the closed-circuit helium technique. II. Normal and abnormal states in man.


The carbon monoxide diffusing capacity of the lung in normal subjects.


Diffuse interstitial pulmonary fibrosis and honeycomb lung.


The nature of leukaemia. II. A histochemical study of the leukaemic cell in the experimental animal.


Fluorescein-globulin affinities for red cells in haemolytic anaemia.


Further observations on the relation between body fluid volume and urine flow in man.


The association of hepatic and renal disease.


The significance of the presence in human serum of complement-fixing antibodies to human tissue antigens.


Calciferol therapy in dermatitis herpetiformis and pityriasis rosea.


Agminate staphylococcal folliculitis: coral reef dermatitis.


Cutaneous leishmaniasis with report of a case.


Biochemical features of cutaneous porphyria and porphyria cutanea tarda.


Plantar warts; a simple method of treatment.


Selective placement and follow-up of industrial employees with cardiovascular disease.


The financing of a teaching hospital: a ten-year comparison (1947-1957).


Observations on home care programs in the United States.


From the little toe to the root of the tongue: a short account of Chinese medicine.


Pratical aspects of early cancer diagnosis.


Current trends in medical education.

Current trends in medical education.


More about student finances.

More about student finances.


Clinical pathological conference: the problem of plasma cell proliferation and abnormal serum lipoproteins.


Physicochemical properties of hyaluronic acid formed by Streptococcus haemolyticus.


Initial stages in the biosynthesis of porphyrins. I. The formation of delta-am-inolaevulic acid by particles obtained from chicken erythrocytes.


The association of adrenaline and noradrenaline with blood platelets.


Spectral methods of characterizing anthocyanins.


A sensitive method for estimation of oxaloacetate.


Studies on phospholipids. 3. Determination of choline.


Studies on phospholipids. 4. Determination of ethanolamine and serine.


Substrates for rumen beta-glucosidase.

Substrates for rumen beta-glucosidase.


Microdetermination of the fatty acids in blood serum.


The effect of soluble silica on the metabolism of rat-tissue preparations.


Some characteristics of the enzymic carboxyl activation of methionine.


Studies on plant flavokinase.

Studies on plant flavokinase.


Studies on the proteins of fish skeletal muscle. 5. Molecular weight and shape of cod fibrillar proteins.


Initial stages in the biosynthesis of porphyrins. 2. The formation of delta-aminolaevulic acid from glycine and succinyl-coenzyme A by particles from chicken erythrocytes.


The changes in the total vitamin B6 and the pyridoxal phosphate content of cells of Bacillus sphaericus during growth and sporulation: their possible relationships with alphaepsilon-diaminopimelic acid metabolism.


A corticotrophin-releasing factor: partial purification and amino acid composition.


The component acids and glycerides of the depot fat of an Indian panther (Panthera pardus fusca).


5-Formylfuroic acid and the carbazole reaction for uronic acids and acidic polysaccharides.


Biochemical studies of toxic agents. 11. The occurrence of premercapturic acids.


Phenolic acids and flavonoids of Theobroma cacao L.; separation and identification by paper chromatography.


Purification of free staphylococcal coagulase.


The phosphotransferase activity of phosphatases. 2. Studies with purified alkaline phosphomonoesterases and some substrate-specific phosphatases.


The phosphotransferase activity of phosphatases. 3. Comparison of enzymic catalysis by acid phosphatase with nonenzymic catalysis at acid pH values.


The phosphotransferase activity of phosphatases. 1. Spectrophotometric methods for the estimation of some phosphate esters and other compounds.


The influence of tannins on the degradation of pectin by pectinase enzymes.


Distribution of ascorbic acid in normal and leukaemic human blood.


Further observations on the oxidation of di-idotyrosine derivatives.


Thetin-homocysteine transmethylase; some further characteristics of the enzyme from rat liver.


The source of proline for casein biosynthesis.


The reactivity of free amino groups in native and denatured ovalbumin towards fluorodinitrobenzene.


Properties and partial purification of kynureninase.


Metabolism of nicotinamide and nicotinic acid in Neurospora crassa.


The metabolism of DL-1-deoxy-1-fluoroglycerol.


Calcium and magnesium metabolism in calves. 2. Effect of dietary vitamin D and ultraviolet irradiation on milk-fed calves.


Formation of antibody by isolated perfused lungs of immunized rabbits: the use of [14C]amino acids to study the dynamics of antibody secretion.


Transphosphorylations catalysed by bivalent metal ions.


The effects of the hyaluronic acid complex on the distribution of ions.


The biosynthetic preparation of [16-3H]aldosterone and [16-3H] corticosterone.


The inhibition of mitosis by the reaction of maleic hydrazide with sulphydryl groups.


Fractionation of proteins of the microsomes of rat liver by means of a non-ionic detergent.


The reaction of peptides and insulin with methylhydrazine.


Phosphate esters in the uterus.

Phosphate esters in the uterus.


The isolation of 16 beta-hydroxyoestrone and 16-oxo-oestradiol-17 beta from the urine of pregnant women.


Preparation of some deoxyribonucleic acid-protein complexes from rat-liver homogenates.


The metabolism of chlorotic leaves. 1. Amino acids.


The metabolism of chlorotic leaves. 2. Organic acids.


The uptake and metabolism of amino acids by slices of carrot.


Kinetic aspects of the uptake of amino acids by carrot tissue.


The relationship of certain enzymes in cobra and rattlesnake venoms to the mechanism of action of these venoms.


The effect of various metabolites on incorporation in vitro of labelled amino acids into protein of normal rat diaphragm.


The labelling by [14C]amino acids of cell-sap protein in a cell-free system from guinea-pig liver: the site of origin of labelled protein.


The relationship of the tricarboxylic acid cycle to the synthesis of delta-aminolaevulic acid in avian erythrocyte preparations.


The effect of pH variations on the activities of Cesterase.


Bound amino acids in protein-free extracts of Italian ryegrass.


Studies in the bile acids. 3. The conjugated bile salts of certain primates.


[Kinetics of the exchange of the fructosyl radical by levansucrase].


The path of carotenoid synthesis in a photosynthetic bacterium.


Galactose-1-phosphate uridyl transferase: its purification and application.


The molecular structure of polyinosinic acid.


A statistical analysis of the order of certain amino acids in the protein of Escherichia coli.


Utilization of amino acids by Bacillus subtilis during growth and antibiotic production.


The chitinase system of a strain of Streptomyces griseus.


Properties of ribonucleic acid turnover in T2-infected Escherichia coli.


A method for the determination of D(-)-lactic acid.


Electrophoretic separation of intermediate compounds in two reactions of ferrihemoglobin.


Quantitative amino acid analysis of food proteins by means of a single ion-exchange column.


Studies on nucleoproteins. VI. The deoxyribonucleoprotien and the deoxyribonucleic acid of bovine tubercle bacilli. (BCG).


On the physical state of the intracellularly accumulates substrates of beta-galactoside-permease in Escherichia coli.


Molecular structural effects produced in proteins by reaction with succinic anhydride.


The isolation and quantitation of the principle phospholipid components of human serum using chromatography on silicic acid.


Investigations of poliomyelitis antigens.


Specific precipitin reactions of the virus of poliomyelitis in gels.


Studies on the mechanism of oxidative phosphorylation. V. The phosphorylating properties of the electron transport particle.


The mechanism of plantvirus infection.

The mechanism of plantvirus infection.


The presence of an uronic acid epimerase in a strain of pneumococcus type I.


Further observations on the N-terminal amino acids of bovine serum albumin.


The inhibition of D-amino acid oxidase by D-lysine.


The effect in vivo of thyroxine on acyl phosphatase of rat liver and muscle.


Preparation and properties of protoplasts of Rhodospirillum rubrum.


Enzymic ribosidation and ribotidation of 5-fluorouracil by extracts of the Ehrlich-ascites tumor.


Vitamin B12 and the metabolism of formate and histidine by the rat.


Enzymic synthesis of N-acetyl-D-mannosamine.


The dependence of 14C-glycine uptake by protein fractions on the ribonucleic acid (RNA) biosynthesis in slices of regenerating rat liver.


Identification of a sulfate conjugate of bilirubin in bile.


5-Keto-L-galactonate as an intermediate in the catabolism of D-galacturonate by Erwinia carotovora.


Solubilization and assay of the insoluble alpha-glycero-phosphate dehydrogenase of animal tissues.


Competitive inhibition of nitrogen fixation by oxygen.


A spectrophotometric titration of ribonuclease in ethylene glycol.


The conversion of D-xylose to xylitol by Penicillum chrysogenum.


Aromatic synthesis in molds: formation of the tropolone, stipitatic acid.


Degradation of intracellular nucleic acid and leakage of fragments by Lactobacillus arabinosus.


An electron-spin-resonance study of the interaction of manganous ions with enolase and its substrate.


Flavin adenine dinucleotide synthesis in animal tissues.


Protein synthesis and RNA turnover in a pyrimidine-deficient bacterium.


The apparent mutagenicity of thymine deficiency.


Synthesis and metabolism of a histamine metabolite, 1-methyl-4 (beta-aminoethyl)-imidazole.


The purification and properties of an alpha-glucosidase of Saccharomyces italicus Y1225.


Purification and physico-chemical properties of laccase.


Studies on the electron transport system. XIII. Mitochondrial structure and dehydrogenase activity in isolated mitochondria.


The isolation and properties of a protease from Proteus vulgaris.


The mechanism of action of fructose diphosphate aldolase.


The proteolytic enzyme system of skin. V. The A2-esterase.


Terminal amino acid residues of chicken, duck and turkey serum albumins.


Substrate specificity and some other properties of baker's yeast hexokinase.


Sialic acids in blood serum.

Sialic acids in blood serum.


Species differences in red blood cell phosphatides separated by column and paper chromatography.


The carboxyl activation of glycine in extracts of Photobacterium fischeri.


Bacterial degradation of creatinine. II. Creatinine desimidase.


The relation of photosynthetic phosphorylation to the Hill reaction.


Inhibition studies on sarcosomal DPNH oxidase.


The inhibition of catalase by boiled tissue extracts.


The acid mucopolysaccharides of connective tissue. III. the sulfate linkage.


A new pathway of uronic acid metabolism.


Residual phospholipase A activity in lysolecithin prepared by the action of snake venom on ovolecithin.


Enzymic conversion of metanephrine to epinephrine.


Enzymic formation of choline sulfate.

Enzymic formation of choline sulfate.


The enzymic synthesis of aryl sulphamates.


Enzymic oxidation of carbon monoxide.

Enzymic oxidation of carbon monoxide.


Amination of uridine nucleotides to cytidine nucleotides by soluble mammalian enzymes; role of glutamine and guanosine nucleotides.


Paired fibrous structure in mycobacteria.


Bound and latent mouse-pancreas ribonucleases.


The effect of thyroid hormones on carbohydrate metabolism in tissue culture.


Catalysis of hydrogen transfer between pyridine nucleotides by 3 alpha-hydroxysteroid dehydrogenase.


An enzymic defect in ascites-tumor cells.


The identity of diaphorase and lipoic dehydrogenase.


Effects of steroids upon galactose oxidation in vitro.


An intramolecular model for an esteratic enzyme.


Photochemical reduction of elementary nitrogen in the blue-green alga Anabaena cylindrica.


Cytochromes and thiosulphate oxidation in an aerobic Thiobacillus.


Animal metabolism of hydroxyproline; isolation and enzymic reactions of gamma-hydroxy-hydroxy-glutamic semialdehyde.


The inhibition of Escherichia coli by 1-penicillamine and its reversal by isoleucine, valine or leucine.


Depolymerization of deoxyribonucleic acid by the juice of soy-bean sprouts.


Confirmation of the structure of imidazoleacetic acid riboside by synthesis.


The role of oxygen in the biosynthesis of unsaturated fatty acids.


A soluble component required for oxidative phosphorylation by a sub-mitochondrial particle from beef heart muscle.


Metabolic pathways of lysolecithin in a soluble rat-liver system.


[Research on the effects of consanguinity in humans].


[Nucleic acids, phospholipids & phosphoproteins in human leukocytes].


Studies on submicroscopic structure of leukemias of known or suspected viral origin: a review.


Selective occurrence of glutathione instability in red blood corpuscles of the various Jewish tribes.


Hypochromic anemias of the tropics associated with pyridoxine and nicotinic acid deficiency.


Chediak's anomaly of leukocytes in malignant lymphoma associated with leukemic manifestations: case report with necropsy.


Paroxysmal nocturnal hemoglobinuria: a case report with a negative Ham presumptive test associated with serum properdin deficiency.


Pernicious anemia, megaloblastosis and the di Guglielmo syndrome.


TRANSFUSION of platelets and platelet substitutes.


PROPOSAL for a certified standard for use in hemoglobinometry: second and final report.


Cesarean sections for cephalopelvic disproportion after previous vaginal deliveries.


Treatment of benign ovarian cystomas.

Treatment of benign ovarian cystomas.


Artificial insemination.

Artificial insemination.


Observations on the nature of great barracuda food poisoning encountered in Puerto Rico.


[Pharmacological value of 1, 4-dicaffeyl-quinic acid (cinarine): a new synthetic choleretic].


[Effects of a cholecystic extract on cholesterol & phospholipid synthesis of the liver & aorta of rats].


[Effects of chronic treatment with steroid hormones & ACTH on the protein pictures of blood & tissues. I. Blood proteins].


The orientation of the heart and the appearance of its chambers in the adult cadaver.


Selective cine-angiocardiography with image intensification.


The correlation between various assessments of pulmonary arterial pressure in mitral stenosis.


The functional and clinical anatomy of the mitral valve.


Residual lung volume in mitral disease.

Residual lung volume in mitral disease.


The electrocardiogram in syphilitic heart disease.


The electrocardiogram in pectus excavatum.


Modification of ventricular gallop rhythm induced by pooling of blood in the extremities.


The aortic lesion of ankylosing spondylitis.


The effect of valvotomy on the murmurs of pulmonary and aortic stenosis.


The cerebral blood flow in mitral stenosis and its response to carbon dioxide.


Foetal paroxysmal auricular tachycardia.


Pulmonary hypertension with special reference to the vasoconstrictive factor.


Pulmonary hypertension in congenital heart disease.


Psychological aspects of obesity.

Psychological aspects of obesity.


Physiological and nutritional aspects of obesity.


Double-barrelled aorta with bacterial endarteritic vegetations.


Myxoma of the left auricle with direct pressure tracings.


J. G. Emanuel.

J. G. Emanuel.


The cardiovascular effects of halothane in normal children.


S.C.T.Z.--a new intravenous anaesthetic?


The treatment of acute respiratory infection in infants.


The role of halothane in prevention of surgical shock.


Carcinoma of the body of the uterus.

Carcinoma of the body of the uterus.


The diagnosis and treatment of renal colic.


Provocative factors in convulsive disorders.


The use of anticoagulants.

The use of anticoagulants.


Dipasic in the treatment of children suffering from primary pulmonary tuberculosis.


Modern hospital lay-out: out-patients' department at St. James' Hospital, Balham.


Medicine in Yugoslavia.

Medicine in Yugoslavia.


Progress report. I. Anaesthesia.

Progress report. I. Anaesthesia.


A new industrial medical department.

A new industrial medical department.


Progress report. II. Ophthalmology.

Progress report. II. Ophthalmology.


The accident syndrome.

The accident syndrome.


The skin clinic.

The skin clinic.


Adeno-carcinoma of the kidney: hypernephroma.


Trichomonas vaginalis in the human male and female.


Fungous infections of the skin.

Fungous infections of the skin.


The danger of tetanus and its prevention.


Streptomycin and hydrocortisone in the local treatment of burns.


Some reflections on ataractics.

Some reflections on ataractics.


Medicine in the United States.

Medicine in the United States.


Acute benign prostatic hypertrophy treated with a new microcirculatory constrictor.


Orthopaedics.

Orthopaedics.


Antibiotics in dermatology.

Antibiotics in dermatology.


Chronic gall bladder disease.

Chronic gall bladder disease.


A review of radiotherapy.

A review of radiotherapy.


Jargon: its clarification and classification.


Rupture of an aortic aneurysm into the pulmonary artery.


The management of preeclamptic toxaemia.


Cardiac injuries.

Cardiac injuries.


Radiotherapy department at Mount Vernon Hospital.


Rubefacient ointments in the treatment of osteoarthritis of the spine.


The treatment of some common disorders. 2. Angina pectoris.


Endocrine and metabolic disorders.

Endocrine and metabolic disorders.


Health needs of youth at work.

Health needs of youth at work.


The skin clinic.

The skin clinic.


Investigations into cantharidin blisters raised on apparently normal skin in normal and abnormal subjects.


Necrobiosis lipoidica.

Necrobiosis lipoidica.


The structure of collagen and elastic tissues in unprocessed skin.


Influence of certain neurotropic drugs on dinitrochlorbenzene eczema in the guinea-pig.


Angiokeratoma corporis diffusum.

Angiokeratoma corporis diffusum.


Urticaria papulosa.

Urticaria papulosa.


Ulcerating and mutilating trophic lesions of the lower limbs.


Effect of interferon on the growth of viruses on the chick chorion.


Some factors affecting the production of interferon.


Distinction between catabolism of native and denatured proteins by the isolated perfused liver after carbon loading.


The chemotherapeutic activity of compounds of copper, rhodium and certain other metals in mice infected with neurovaccinia and ectromelia viruses.


The properties of crystalline diphtheria toxin-protein: observations on the pepsin and trypsin-stable antigens.


Cytochemical and electron microscopical observations on substances associated with fluorocarbon purified vaccinia virus.


The serological specificity and cross-reactivity of some Shigella flexneri extracts.


Further observations on the mode of multiplication of herpes virus.


Quantitative study of the metabolic activity of the Kupffer cells on a heatdenatured serum albumin labelled with 1311.


Visna of sheep; a slow, demyelinating infection.


Factors affecting growth and glycolysis in tissue culture.


The role of the tissue mast cell in experimental atherosclerosis.


Antibody production by single cells.

Antibody production by single cells.


The effect of hydralazine (L-hydrazinophthalazine) on the kidneys of rats treated with cortexone.


Specificity and comparative activity of the carbonic anhydrase inhibitors neptazane and diamox on animal and human eyes.


Intra-ocular foreign body.

Intra-ocular foreign body.


Cybernetics of ocular movement.

Cybernetics of ocular movement.


Benzocaine-urethane solution in ophthalmology.


Histological significance of hemispherical bodies in the eye.


Familial macular defects.

Familial macular defects.


Penetration of sodium and thiocyanate into the posterior and anterior chambers.


Alternative to the 3-snip operation for lacrimal drainage insufficiency.


Amblyopia due to ethyl alcohol.

Amblyopia due to ethyl alcohol.


Complete ophthalmoplegia in acute toxic polyneuritis.


Unusual traumatic deformity of the lens.


Glaucoma following radiotherapy.

Glaucoma following radiotherapy.


A comparison of some pharmacological properties of dioscorine and dioscine. The alkaloids, dioscorine and dioscine, both obtained from yams, have been compared in respect of their convulsant activity, toxicity, analeptic action, local anaesthetic activity, adrenaline potentiating action, antidiuretic effect, and anti-acetylcholine activity. The alkaloids have similar properties, but in most respects dioscorine was the more potent. Aqueous solutions of dioscine are unstable.


The effect of (+)-lysergic acid diethylamide and other drugs on the carotid sinus reflex. In cats, lysergic acid diethylamide (LSD) selectively blocked the reflex blood pressure rise following carotid chemoreceptor stimulation. It also reduced or abolished the chemoreceptor component of the pressor response to occlusion of the common carotid arteries. It did not inhibit the respiratory reflexes arising from the carotid chemoreceptors, unless spontaneous respiration was interfered with as a whole. The site of action was central, probably below the intercollicular level, regardless of whether the drug was administered by the intravenous route or into the lateral ventricle of the brain.LSD did not block the baroreceptor depressor reflex elicited by stimulation of one carotid sinus nerve. LSD frequently caused the systemic pressure to fall, even after vagotomy and atropine, and this effect might account for the occasional reduction of the baroreceptor component of the carotid occlusion response. On the other hand, no relationship was found between the action of LSD on vasomotor tone and its blocking effect on the chemoreceptor pressor reflex.Some derivatives of LSD produced effects similar to those described for LSD, whether or not they possessed a psychotropic action in man, and independently of their efficiency as antagonists to 5-hydroxytryptamine. Of a series of compounds chemically unrelated to LSD, chlorpromazine was found to block the chemoreceptor pressor rise after intracerebroventricular injection.


Local action of some antibacterial substances against Corynebacterium ovis in guinea-pig skin. When a suspension of living Corynebacterium ovis was injected intradermally in guinea-pigs, a lesion of roughly circular outline developed within 24 hr. Lesions of smaller diameter arose if benzylpenicillin, dequalinium, hedaquinium, cetrimide, or oxytetracycline were injected at the identical site, either before, with, or after C. ovis. Evidence has been obtained that such reductions of lesion diameter are due to direct action of drugs on bacteria and not to antitoxic or anti-inflammatory actions. Lesion diameters became less as drug dosage increased up to a limit, and these reductions provided a measure of local antibacterial action in vivo. Intradermal injection of higher concentrations of antibacterials, without C. ovis, produced comparable but somewhat flatter lesions, diameters of which increased with increasing concentration of drug and provided a measure of intradermal toxicity.


Supersensitivity of the vessels of the parotid gland after denervation. Section of the postganglionic parasympathetic nerves to the parotid gland of the cat was found to cause supersensitivity of the blood vessels of the gland towards adrenaline. No supersensitivity or a slight degree only was found after cutting the preganglionic parasympathetic nerves to the gland. No supersensitivity of the vessels of the parotid gland could be demonstrated after excision of the superior cervical ganglion.


The trypanocidal activity of some pyrimidylaminophenylarsonic compounds. A series of substituted pyrimidylaminophenylarsonic acids have been prepared, reduced to the corresponding oxophenylarsines and finally, in certain cases, to the arsenobenzenes. The tervalent arsenicals were highly active against Trypanosoma rhodesiense in mice. 4-(2:6-Diaminopyrimid-4-ylamino)phenyloxoarsine either as the insoluble carbonate or the soluble isethionate was the most promising of these compounds.


The effect of drugs on spontaneous motility and on response to stimulation of the extrinsic nerves of the gut of a teleostean fish. Trout gut shows, in addition to changes in general muscle tone, longitudinal "pendular" rhythms, peristaltic waves, and longitudinal "colic" contractions. Both vagus and splanchnic nerves are motor and there is no evidence of antagonistic "sympathetic" and "parasympathetic" nervous control. A posterior autonomic nerve supplying the rectum stimulated or inhibited according to the duration and frequency of the electrical pulses applied. Acetylcholine increased the tone and amplitude of pendular movements in all regions of the gut, and produced strong contraction of the circular muscles. Both nicotine and hexamethonium antagonized the action of acetylcholine, suggesting that its principal site of action is the neurone. Adrenaline lowered the tone of the longitudinal muscle and abolished pendular activity in the intestine and rectum, but contracted the longitudinal and circular muscles of the stomach. Hexamethonium bromide abolished peristalsis but greatly increased the amplitude of pendular contractions.The reaction of the trout intestine to both histamine and pilocarpine was slight, but nicotine, 5-hydroxytryptamine, eserine, and barium caused strong contractions. The actions of atropine and piperoxan (933F) are discussed. Evidence is presented which suggests that the postganglionic vagus nerve fibres supplying the trout stomach may be adrenergic, while both the splanchnic nerve fibres to the stomach and intestine, and the preganglionic vagal fibres to the stomach, may be cholinergic. It is also suggested that there is a continuous release of acetylcholine by cholinergic neurones in the gut wall.


The schistosomicidal and toxic effects on some alphaomega-di (p-aminophenoxy)alkanes and related monoamines. An account is given of the results obtained with a number of p-aminophenoxyalkanes which were examined for activity against Schistosoma mansoni in mice and for the presence of retinotoxicity in cats. The first compound to be found active, 1:5-di(p-aminophenoxy)-pentane dihydrochloride (M & B 968A), was modified in a variety of ways in an attempt to increase its activity and to eliminate its ocular effects. It was found that a p-aminophenoxyalkyl group was common to all the active compounds, but that the rest of the molecule could be any of several different groups, including alkoxy, phenoxy, and phenyl groups, without diminishing the activity. Although at least one p-aminophenoxyalkyl group was essential for schistosomicidal activity, ocular toxicity was also shown by a p-aminophenylalkyl derivative in which the ether linkage was absent.


Slow-contracting substances in human urine. A method has been developed for purifying the principle in human urine causing contraction of the rat uterus. The method, based on adsorption on the cation exchange resin Amberlite IRC-50, is better suited for dealing with large quantities of urine than the method of Gomes (1955). The presence of the two active fractions described by Walaszek (1957) has been confirmed by a different method.


The action of cysteamine and synkavit on gastric emptying in the normal and irradiated rat. A radiographic method for studying the delay in gastric emptying in the rat caused by whole body irradiation has been applied to the investigation of two compounds which modify the effects of irradiation. The method may be of general use in the study of the action of drugs. Synkavit, which can potentiate the lethal effects of irradiation on tumours, caused a delay in gastric emptying. When Synkavit and irradiation were combined, a simple summation of the delays produced by each of these agents occurred. Cysteamine, which gives some protection against the lethal action of x-rays, also caused a delay in gastric emptying. It did not protect against the action of x-rays on stomach emptying.


The effect of cooling and of 5-hydroxytryptamine on the peristaltic reflex of the isolated guinea-pig ileum. Cooling the guinea-pig ileum to 19 to 26 degrees abolished the emptying phase of the peristaltic reflex. The effects of cooling to 10 degrees were usually reversible, but cooling to 5 degrees for 3 to 8 hr. produced an irreversible decrease in or abolition of the emptying phase. 5-Hydroxytryptamine (5-HT) added in low concentrations to the fluid outside the intestine restored slight peristaltic activity after this activity had been abolished by cooling. If the peristalsis had been depressed but not abolished by cooling, 5-HT in the bath sometimes abolished it. 5-HT introduced into the lumen of the cooled gut regularly restored or increased peristaltic activity. This action was prevented by previous injection of 2-bromolysergic acid diethylamide into the lumen. It is suggested that, when introduced into the lumen, 5-HT may sensitize the sensory receptors in the mucosa of the cooled intestine. When applied outside, 5-HT may facilitate transmission at synapses involved in the peristaltic reflex arc, the excitability of which has been depressed by cooling.


Potentiation of the response of frog rectus muscle to acetylcholine by isopropyl methyl phosphonofluoridate and its modification by pyridine-2-aldoxime methiodide. Pyridine-2-aldoxime methiodide (P2AM) was used to study the relation between the recovery of cholinesterase activity of isolated frog rectus abdominis muscle and the change of isotonic response to acetylcholine after previous treatment with the anticholinesterase, isopropyl methyl phosphonofluoridate (sarin). Addition of P2AM to muscle which had been incubated with sarin produced an 88% decrease in potentiation to acetylcholine. This was accompanied by 71% and 35% recoveries of the cholinesterase activity of the intact and finely ground muscle respectively compared with controls from the contralateral muscle. Following pre-treatment with sarin, a two-hour rinsing with acetylcholine (3 mug./ml.) produced a 61% decrease in potentiation to acetylcholine accompanied by 24% and 4.5% recoveries of cholinesterase activity in intact and in ground muscle respectively. Since control experiments showed absence of uncombined sarin in the muscle after rinsing with acetylcholine solution, the results indicate a greater effectiveness of P2AM and acetylcholine in reactivating superficially situated cholinesterase of the frog rectus abdominis as compared with enzyme within the interior of the muscle.


Effect of pyridine aldoximes on response of frog rectus muscle to acetylcholine. The effects of pyridine-2, 3- and 4-aldoxime methiodide (PAM) on the isotonic contracture of the isolated frog rectus abdominis muscle elicited by acetylcholine have been studied. The potentiation to acetylcholine resulting from incubation with PAM isomers is reversible and may be related to the weak anticholinesterase property of these compounds. Concentrations of the isomers higher than those needed for maximal potentiation produce a reversible block of the muscle to acetylcholine. pH studies suggest that cations are responsible for the potentiating and blocking properties of the PAM isomers.


The mode of action of quinidine on isolated rabbit atria interpreted from intracellular potential records. An attempt has been made to show why quinidine, which has long been known not to lengthen the duration of the cardiac action potential, measured with external electrodes, and also not to lengthen, and sometimes to shorten, the absolute refractory period, nevertheless reduces the maximum frequency at which atria can respond to a stimulus. Simultaneous measurements have been made in electrically driven isolated rabbit atria of contractions, conduction velocity and intracellular potentials before and during exposure to a wide range of concentrations of quinidine sulphate. The resting potential remained undiminished, in contrast to the effect of quinidine on Purkinje fibres. In the therapeutic range of doses, up to 10 mg./l., the half-time for repolarization was either shortened or unchanged, thus providing an explanation for the failure of quinidine to prolong the absolute refractory period. In contrast, even at low concentrations of quinidine, conduction velocity and the rate of rise of the action potential were greatly slowed, and the height of the overshoot was reduced. The terminal phase of the action potential was prolonged. It is known that the rate of rise of the action potential is a function of the level of repolarization at which an impulse takes off (the more negative the take-off point, the faster the rate of rise). Normally, a stimulus introduced when repolarization has proceeded to 2/3 of the resting potential evokes a response with a rate of rise fast enough for propagation, so that the duration of the terminal 1/3 of the phase of repolarization has no influence upon the length of the effective refractory period. In the presence of quinidine, however, the rate of rise itself was directly reduced, thus repolarization had to proceed further before the critical take-off point was reached at which the rate of rise was fast enough for propagation, and the duration of the terminal phase of repolarization thus became significant. It has been concluded that quinidine prolongs the effective refractory period by slowing the phase of depolarization, without any change necessarily occurring in the half-time for repolarization, which determines the absolute refractory period. Acetylcholine accelerated the rate of rise of the action potential even in the presence of high concentrations of quinidine.


The inhibitory action of morphine on the contraction of the longitudinal muscle coat of the isolated guinea-pig ileum. Morphine (0.05 to 0.1 mug./ml.) markedly inhibited the contractions of the isolated guinea-pig ileum caused by nicotine, barium, and 5-hydroxytryptamine while the actions of acetylcholine, carbachol, and histamine were affected only a little. Atropine (0.025 to 0.05 mug./ml.) had a similar effect, in addition to its known effects on acetylcholine and carbachol contractions. Morphine had no additional effect on the inhibitory action of atropine, while in the presence of morphine, atropine had a significant additional inhibitory action only on the contraction caused by nicotine.The action of barium was complex. It caused contractions of a rhythmic type alternating with relaxations, a pattern which is similar to that produced by the emptying phase of the peristaltic reflex; these oscillations were inhibited by hexamethonium. On the other hand, that part of the sustained barium contraction which was inhibited by morphine may be explained by an action on the nerve cells innervating the muscle fibres (motor neurones). Similarly, the morphinesensitive component of the 5-hydroxytryptamine (5-HT) contraction was probably also due to an action on the motor neurones. The morphine-insensitive contractions of barium, 5-HT, and nicotine were believed to be caused by a direct action on the muscle fibres.The morphine inhibitors, nalorphine and levallorphan, had different effects with the different agonists. Their morphine-like action was particularly pronounced on the effect of 5-HT, which they antagonized, while their morphine-protecting action was most strongly present on the effect of nicotine.